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  1. PREFACE: Proceedings of the 7th International LISA Symposium, Barcelona, Spain, 16-20 June 2008

    NASA Astrophysics Data System (ADS)

    Lobo, Alberto; Sopuerta, Carlos F.

    2009-07-01

    In June 2006 the LISA International Science Team (LIST) accepted the bid presented by the Institut d'Estudis Espacials de Catalunya (IEEC) to host the 7th International LISA Symposium. This was during its 11th meeting at the University of Maryland, just before the 6th edition of the Symposium started in NASA's Goddard Space Flight Center. The 7th International LISA Symposium took place at the city of Barcelona, Spain, from 16-20 June 2008, in the premises of CosmoCaixa, a modern Science Museum located in the hills near Tibidabo. Almost 240 delegates registered for the event, a record breaking figure compared to previous editions of the Symposium. Many of the most renowned world experts in LISA, Gravitational Wave Science, and Astronomy, as well as Engineers, attended LISA 7 and produced state-of-the-art presentations, while everybody benefited from the opportunity to have live discussions during the week in a friendly environment. The programme included 31 invited plenary lectures in the mornings, and 8 parallel sessions in the afternoons. These were classified into 7 major areas of research: LISA Technology, LISA PathFinder, LISA PathFinder Data Analysis, LISA Data Analysis, Gravitational Wave sources, Cosmology and Fundamental Physics with LISA and Other Gravitational Wave Detectors. 138 abstracts for communications were received, of which a selection was made by the session convenors which would fit time constraints. Up to 63 posters completed the scientific programme. More details on the programme, including some of the talks, can be found at the Symposium website: http://www.ice.cat/research/LISA_Symposium. There was however a remarkable add-on: Professor Clifford Will delivered a startling presentation to the general public, who completely filled the Auditori—the main Conference Room, 320 seats—and were invited to ask questions to the speaker who had boldly guided them through the daunting world of Black Holes, Waves of Gravity, and other Warped Ideas of

  2. EDITORIAL: Proceedings of the 7th International LISA Symposium, Barcelona, Spain, 16-20 June 2008 Proceedings of the 7th International LISA Symposium, Barcelona, Spain, 16-20 June 2008

    NASA Astrophysics Data System (ADS)

    Lobo, Alberto; Sopuerta, Carlos F.

    2009-05-01

    In June 2006 the LISA International Science Team (LIST) accepted the bid presented by the Institut d'Estudis Espacials de Catalunya (IEEC) to host the 7th International LISA Symposium. This was during its 11th meeting at the University of Maryland, just before the 6th edition of the symposium started at NASA's Goddard Space Flight Center. The 7th International LISA Symposium took place in the city of Barcelona, Spain, 16-20 June, 2008, in the premises of CosmoCaixa, a modern science museum located in the hills near Tibidabo. Almost 240 delegates registered for the event, a record breaking figure compared to previous editions of the symposium. Many of the most renowned world experts in LISA, gravitational wave science, and astronomy, as well as engineers, attended LISA #7 and produced state of the art presentations, while everybody benefited from the opportunity to have live discussions during the week in a friendly environment. The programme included 31 invited plenary lectures in the mornings, and eight parallel sessions in the afternoons. These were classified into seven major areas of research: LISA Technology, LISA PathFinder, LISA PathFinder Data Analysis, LISA Data Analysis, Gravitational Wave Sources, Cosmology and Fundamental Physics with LISA and Other Gravitational Wave Detectors. Abstracts for 138 communications were received, from which a selection was made by the session convenors which would fit time constraints. Up to 63 posters completed the scientific programme. More details on the programme, including some of the talks, can be found at the symposium website:http://www.ice.cat/research/LISA_Symposium. There was, however, a remarkable add-on: Professor Clifford Will delivered a startling presentation to the general public, who completely filled the Auditori—the main conference room, 320 seats—and were invited to ask questions to the speaker who boldly guided them through the daunting world of Black Holes, Waves of Gravity, and other Warped Ideas

  3. 7th International Meshing Roundtable '98

    SciTech Connect

    Eldred, T.J.

    1998-10-01

    The goal of the 7th International Meshing Roundtable is to bring together researchers and developers from industry, academia, and government labs in a stimulating, open environment for the exchange of technical information related to the meshing process. In the past, the Roundtable has enjoyed significant participation from each of these groups from a wide variety of countries.

  4. PREFACE: 10th International LISA Symposium

    NASA Astrophysics Data System (ADS)

    Ciani, Giacomo; Conklin, John W.; Mueller, Guido

    2015-05-01

    The LISA Symposia have become a mainstay of the gravitational wave community. Held every two years, they are the prime opportunity for our community to discuss the exciting science, technology, mission designs, and progress of the Laser Interferometer Space Antenna. The 8th LISA symposium, held at Stanford University in the summer of 2010 was the largest symposium so far and was dominated by progress and hopes that the LISA mission will soon excel following the expected launch of the LISA pathfinder (LPF), no later than 2012, and the expected prioritization by the Decadal survey which was released 6 weeks later. The following years were challenging. Although the Decadal survey ranked LISA very high, NASA's budget issues, mostly due to the cost increase of the James Webb Space Telescope, and continued delays in LPF put too much stress on the LISA project and it officially ended in 2011. The LISA International Science Team (LIST), the core group of LISA scientists and technologists, was dissolved and the community in the U.S. was struggling to maintain cohesion. In the wake of these events, ESA started a new selection process for their next three large missions, L1, L2, and L3, and the European LISA team developed the New Gravitational wave Observatory (NGO), an evolved LISA concept, as an ESA only L1 candidate. A few weeks before the 9th LISA Symposium, held in Paris in May 2012, ESA announced its decision to select JUICE, a planetary mission to Jupiter and its moons, as its next large science mission (L1). Despite having the highest ranked science case, NGO was not selected due to further delays in LPF and the general feeling outside the GW community that the technology is perhaps too challenging to be pulled off in time for the L1 launch in 2022. Many U.S. members of the LISA community cancelled their travel plans and the mood at that symposium ranged from resignation to defiance. Hope for a somewhat timely launch of a LISA-like mission rested upon L2, the next

  5. 7th International Immunoglobulin Conference: Interlaken Leadership Awards.

    PubMed

    Dalakas, M C; Löscher, W N

    2014-12-01

    The Interlaken Leadership Awards (ILAs), established in 2010, are monetary grants pledged annually by CSL Behring to fund research into the use of immunoglobulin (Ig) therapy, especially into its use in neurological disorders. Five recipients of the 2011/2012 Awards were invited to present their research at the 7th International Immunoglobulin Conference. Dr Honnorat reports on paraneoplastic neurological syndromes (PNS). His multi-centre Phase II trial, currently under way, will assess the efficacy of IVIg therapy in treating PNS in the first 3 months of treatment. Dr Geis shows improved disease scores after IVIg treatment in a mouse model of neuromyelitis optica (NMO). It is hoped that these promising results will translate well into human NMO. Dr Schmidt studied IVIg therapy in an mdx mouse model for Duchenne muscular dystrophy (DMD). He reports that motor function improved and myopathic changes in skeletal muscles and creatine kinase release were decreased. Dr Gamez presents the design and rationale for a Phase II clinical trial investigating the preoperative use of IVIg therapy in myasthenia gravis patients to prevent post-operative myasthenic crisis. Dr Goebel reports results from studies elucidating the immune-mediated pathogenesis of complex regional pain syndrome (CRPS), the successful IVIg therapy in a proportion of CRPS patients, and the development of a model for predicting which patients are more likely to respond to Ig therapy.

  6. 7th IGRSM International Remote Sensing & GIS Conference and Exhibition

    NASA Astrophysics Data System (ADS)

    Shariff, Abdul Rashid Mohamed

    2014-06-01

    IGRSM This proceedings consists of the peer-reviewed papers from the 7th IGRSM International Conference and Exhibition on Remote Sensing & GIS (IGRSM 2014), which was held on 21-22 April 2014 at Berjaya Times Square Hotel, Kuala Lumpur, Malaysia. The conference, with the theme Geospatial Innovation for Nation Building was aimed at disseminating knowledge, and sharing expertise and experiences in geospatial sciences in all aspects of applications. It also aimed to build linkages between local and international professionals in this field with industries. Highlights of the conference included: Officiation by Y B Datuk Dr Abu Bakar bin Mohamad Diah, Deputy Minister of Minister of Science, Technology & Innovation Keynote presentations by: Associate Professor Dr Francis Harvey, Chair of the Geographic Information Science Commission at the International Geographical Union (IGU) and Director of U-Spatial, University of Minnesota, US: The Next Age of Discovery and a Future in a Post-GIS World. Professor Dr Naoshi Kondo, Bio-Sensing Engineering, University of Kyoto, Japan: Mobile Fruit Grading Machine for Precision Agriculture. Datuk Ir Hj Ahmad Jamalluddin bin Shaaban, Director-General, National Hydraulic Research Institute of Malaysia (NAHRIM), Malaysia: Remote Sensing & GIS in Climate Change Analyses. Oral and poster presentations from 69 speakers, from both Malaysia (35) and abroad (34), covering areas of water resources management, urban sprawl & social mobility, agriculture, land use/cover mapping, infrastructure planning, disaster management, technology trends, environmental monitoring, atmospheric/temperature monitoring, and space applications for the environment. Post-conference workshops on: Space Applications for Environment (SAFE), which was be organised by the Japan Aerospace Exploration Agency (JAXA) Global Positioning System (GPS) Receiver Evaluation Using GPS Simulation, which was be organised by the Science & Technology Research Institute for Defence

  7. The 7th International Workshop on Chiral Dynamics

    NASA Astrophysics Data System (ADS)

    The 7th International Workshop Chiral Dynamics: Theory and Experiment (CD12) took place at Jefferson Lab, Newport News, Virginia, USA, from August 6 to 10, 2012. Following in the tradition of this triennial series of Conferences, it attracted theorists and experimentalists, who were brought together to highlight the recent progress in the field of low energy QCD, and to discuss and explore the direction for future development. The conference consisted of plenary talks and three working groups. We would like to thank the working group organizers for their dedicated effort, namely: Goldstone Bosons: Mario Antonelli, Liping Gan, Jorge Portoles and Urs Wenger; Hadron Structure: Alessandro Bacchetta, Bastian Kubis, Kostas Orginos and Karl Slifer and Few Body Physics: Andreas Nogga, Assumpta Parreno, Michele Viviani and Henry Weller. We would like to express our special thanks to our co-organizers, Patricia Solvignon, Harald Griesshammer, Rocco Schiavilla, Dinko Pocanic, Robert Edwards, and Alexandre Deur for their hard work and advice. Last but not least, we thank the International Advisory Committee for their very useful inputs to the CD12 program. The organizers thank the excellent logistic and administrative support provided by the Jefferson Lab Conference Staff, Ruth Bizot, Cynthia Lockwood, Stephanie Vermeire, Marti Hightower and MeLaina Evans, and the Conference Secretary Mary Fox, which was instrumental for the success of the organization of CD12. We thank Joanna Griffin for the poster design. CD12 was primarily sponsored by Jefferson Lab, along with generous supports from Old Dominion University and the European Physics Journal. The CD12 homepage is located at http://www.jlab.org/conference/CD12 The upcoming Chiral Dynamics Workshop will take place in Pisa, Italy, in 2015. We thank Laura Marcucci and Michele Viviani for graciously taking the baton from us. Jose Goity and Jianping Chen

  8. 7th International Conference on Mathematical Methods in Physics

    NASA Astrophysics Data System (ADS)

    Bonora, L.; Bytsenko, A. A.; Guimarães, M. E. X.; Helayël-Neto, J. A.

    The 7th International Conference on Mathematical Methods in Physics took place in the Centro Brasileiro de Pesquisas Físicas (CBPF/MCT), Rio de Janeiro - RJ, Brazil, from 16 to 20 April 2012, and was jointly organized by the following Institutions: Centro Brasileiro de Pesquisas Físicas (CBPF/MCT), The Abdus Salam International Centre for Theoretical Physics (ICTP, Italy), Instituto Nacional de Matemática Pura e Aplicada (IMPA, Brazil), The Academy of Sciences for the Developing World (TWAS, Italy) and The Scuola Internazionale di Studi Avanzati (SISSA,Italy). The Organizing Committees were composed by: E. ABDALLA (USP, Brazil), L. BONORA (SISSA, Italy), H. BURSZTYN (IMPA, Brazil), A. A. BYTSENKO (UEL, Brazil), B. DUBROVIN (SISSA, Italy), M.E.X. GUIMARÃES (UFF, Brazil), J.A. HELAYËL-NETO (CBPF, Brazil). Advisory Committee: A. V. ASHTEKAR (Penn State University, U.S.A.), V. M. BUCHSTABER (Steklov Mathematical Institute, Russia), L. D. FADDEEV (St. Petersburg Dept. of Steklov Mathematical Institute, Russia), I. M. KRICHEVER (Columbia Univ., U.S.A./ Landau Institute of Theoretical Physics, Russia), S. P. NOVIKOV (Univ. of Maryland, U.S.A./Landau Institute of Theoretical Physics, Russia), J. PALIS (IMPA, Brazil), A. QADIR (National University of Sciences and Technology, Pakistan), F. QUEVEDO (ICTP, Italy), S. RANDJBAR-DAEMI (ICTP, Italy), G. THOMPSON (ICTP, Italy), C. VAFA (Harvard University, U.S.A.). The Main Goal: The aim of the Conference was to present the latest advances in Mathematical Methods of Physics to researchers, young scientists and students of Latin America in general, and Brazil in particular, in the areas of High Energy Physics, Cosmology, Mathematical Physics and Applied Mathematics. The main goal was to promote an updating of knowledge and to facilitate the interaction between mathematicians and theoretical physicists, through plenary sessions and seminars. This Conference can be considered as a part of a network activity in a special effort to

  9. PREFACE: 7th EEIGM International Conference on Advanced Materials Research

    NASA Astrophysics Data System (ADS)

    Joffe, Roberts

    2013-12-01

    The 7th EEIGM Conference on Advanced Materials Research (AMR 2013) was held at Luleå University of Technology on the 21-22 March 2013 in Luleå, SWEDEN. This conference is intended as a meeting place for researchers involved in the EEIGM programme, in the 'Erasmus Mundus' Advanced Materials Science and Engineering Master programme (AMASE) and the 'Erasmus Mundus' Doctoral Programme in Materials Science and Engineering (DocMASE). This is great opportunity to present their on-going research in the various fields of Materials Science and Engineering, exchange ideas, strengthen co-operation as well as establish new contacts. More than 60 participants representing six countries attended the meeting, in total 26 oral talks and 19 posters were presented during two days. This issue of IOP Conference Series: Materials Science and Engineering presents a selection of articles from EEIGM-7 conference. Following tradition from previous EEIGM conferences, it represents the interdisciplinary nature of Materials Science and Engineering. The papers presented in this issue deal not only with basic research but also with applied problems of materials science. The presented topics include theoretical and experimental investigations on polymer composite materials (synthetic and bio-based), metallic materials and ceramics, as well as nano-materials of different kind. Special thanks should be directed to the senior staff of Division of Materials Science at LTU who agreed to review submitted papers and thus ensured high scientific level of content of this collection of papers. The following colleagues participated in the review process: Professor Lennart Walström, Professor Roberts Joffe, Professor Janis Varna, Associate Professor Marta-Lena Antti, Dr Esa Vuorinen, Professor Aji Mathew, Professor Alexander Soldatov, Dr Andrejs Purpurs, Dr Yvonne Aitomäki, Dr Robert Pederson. Roberts Joffe October 2013, Luleå Conference photograph EEIGM7 conference participants, 22 March 2013 The PDF

  10. Proceedings of the 7th International Symposium on the Molecular Breeding of Forage and Turf

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The 7th International Symposium on the Molecular Breeding of Forage and Turf, MBFT2012, was held in Salt Lake City, UT, USA, from 4-7 June 2012. One-hundred and fifteen researchers from around the world presented oral and poster formats relating to ten general topics: Genetic mechanisms and applic...

  11. Proceedings from the 7th Annual International Society for Musculoskeletal Imaging in Rheumatology (ISEMIR) conference.

    PubMed

    Troum, Orrin M; Pimienta, Olga L; Schmidt, Wolfgang A; Ostergaard, Mikkel; D'Agostino, Maria Antonietta; Gaylis, Norman; Arnold, William; Ben-Artzi, Ami; Ranganath, Veena; Seraphine, Judy L; Peterfy, Charles

    2015-08-01

    The International Society for Musculoskeletal Imaging in Rheumatology (ISEMIR) was founded in 2005 with the goal of discussing matters related to imaging in rheumatology, particularly, validation, education, and use in clinical practice and research. Because the field of musculoskeletal (MSK) imaging is rapidly evolving, continuous education in the field is imperative. ISEMIR's international faculty and world-renowned experts presented the newest information as it relates to the use of magnetic resonance imaging (MRI) and ultrasound (US) at the 7th annual ISEMIR meeting which took place on April 12-14, 2014 in Santa Monica, California. Presentations from the meeting can be viewed at www.isemir.org.

  12. PREFACE: 7th Asian International Seminar on Atomic and Molecular Physics

    NASA Astrophysics Data System (ADS)

    Deshmukh, Pranawa C.; Chakraborty, Purushottam; Williams, Jim F.

    2007-09-01

    These proceedings arose from the 7th Asian International Seminar on Atomic and Molecular Physics (AISAMP) which was held at the Indian Institute of Technology, Madras from 4-7 December 2006. The history of the AISAMP has been reviewed by Takayanagi http://www.physics.iitm.ac.in/~aisamp7/history.html. This international seminar/conference series grew out of the Japan-China meetings which were launched in 1985, the fourth of which was held in 1992 and carried a second title: The First Asian International Seminar on Atomic and Molecular Physics (AISAMP), thus providing a formal medium for scientists in this part of the world to report periodically and exchange their scientific thoughts. The founding nations of Japan and China were joined subsequently by Korea, Taiwan, India and Australia. The aims of the symposia included bringing together leading experts and students of atomic and molecular physics, the discussion of important problems, learning and sharing modern techniques and expanding the horizons of modern atomic and molecular physics. The fields of interest ranged from atomic and molecular structure and dynamics to photon, electron and positron scattering, to quantum information processing, the effects of symmetry and many body interactions, laser cooling, cold traps, electric and magnetic fields and to atomic and molecular physics with synchrotron radiation. Particular interest was evident in new techniques and the changes of the physical properties from atomic to condensed matter. Details of the 7th AISAMP, including the topics for the special sessions and the full programme, are available online at the conference website http://www.physics.iitm.ac.in/~aisamp7/. In total, 95 presentations were made at the 7th AISAMP, these included the Invited Talks and Contributed Poster Presentations, of which 52 appear in the present Proceedings after review by expert referees, refereed to the usual standard of the Institute of Physics journal: Journal of Physics B: Atomic

  13. International Symposium on Plant Lipids (7th) Held in Davis, California on 27-31 July 1986.

    DTIC Science & Technology

    1986-07-31

    Medium & Long Chain Biosynthesis, (7) Interaction of Federal, Industrial <a * Academic Research, Q8) Algal Lipids , and J?) The Future - Genetics & Biotech...i DT1C EECTE N OCT15 0UU ~0 Final Report 7th International Symposium on Plant Lipids 0Davis, CA, July 27-31, 1986 Prepared by P.K. Stumpf...41 %*t % 05 %p~~ a-a % %; The 7th International Symposium of Structure and Function of Plant Lipids was held on the Davis Campus of the University of

  14. PREFACE: 7th International Conference on Cooling & Heating Technologies (ICCHT 2014)

    NASA Astrophysics Data System (ADS)

    2015-09-01

    The Kyoto protocol has initiated a pledge from almost all developing and developed countries to be committed to reducing CO2 emissions. Development of new renewable energy technologies are also of interest in this conference. Greenhouse gases have contributed to global warming and other man-made disasters. Cooling and Heating communities also have responsibilities towards the commitment of reducing the greenhouse gas emissions. In addition, depleting natural resources also act as a threat to the Cooling and Heating industries, causing them to develop highly efficient equipment and innovative technologies. The 1st International Conference on Cooling & Heating Technologies was held in Hanoi Vietnam (Jan. 2005). Whereas the 2nd, 3rd, 4th and 5th ICCHT conferences were held in Dalian, China (Jul. 2006), Tokyo, Japan (Jul. 2007), Jinhae, Korea (Oct. 2008) and Bandung, Indonesia (Dec. 2010) respectively. The 6th International Conference on Cooling & Heating Technologies (ICCTH2012) was held in Xi'an in China on November 9-12, 2012. It is our pleasure to welcome you to the 7th International Conference on Cooling & Heating Technologies (ICCTH2014) on 4th - 6th November 2014 at the Grand Dorsett Subang Hotel, Subang Jaya, Selangor Darul Ehsan, Malaysia The Theme of the Conference is ''Sustainability and Innovation in Heating & Cooling Technologies''. The sub-themes are:- • CO2 Reduction and Low Carbon Technologies • HVAC System and Natural Ventilation • Energy & Alternative Energy • Computational Fluid Dynamics • Low Temperature & Refrigeration Engineering In conjunction with the Conference, an Exhibition will be organized as an integral part of the Conference. Project experiences, product solutions, new applications and state-of-the art information will be highlighted.

  15. 7th International Workshop on Microbeam Probes of Cellular Radiation Response

    SciTech Connect

    Brenner, David J.

    2009-07-21

    The extended abstracts that follow present a summary of the Proceedings of the 7th International Workshop: Microbeam Probes of Cellular Radiation Response, held at Columbia University’s Kellogg Center in New York City on March 15–17, 2006. These International Workshops on Microbeam Probes of Cellular Radiation Response have been held regularly since 1993 (1–5). Since the first workshop, there has been a rapid growth (see Fig. 1) in the number of centers developing microbeams for radiobiological research, and worldwide there are currently about 30 microbeams in operation or under development. Single-cell/single-particle microbeam systems can deliver beams of different ionizing radiations with a spatial resolution of a few micrometers down to a few tenths of a micrometer. Microbeams can be used to addressquestions relating to the effects of low doses of radiation (a single radiation track traversing a cell or group of cells), to probe subcellular targets (e.g. nucleus or cytoplasm), and to address questions regarding the propagation of information about DNA damage (for example, the radiation-induced bystander effect). Much of the recent research using microbeams has been to study low-dose effects and ‘‘non-targeted’’ responses such as bystander effects, genomic instability and adaptive responses. This Workshop provided a forum to assess the current state of microbeam technology and current biological applications and to discuss future directions for development, both technological and biological. Over 100 participants reviewed the current state of microbeam research worldwide and reported on new technological developments in the fields of both physics and biology.

  16. PREFACE: 7th International Conference on Modern Practice in Stress and Vibration Analysis

    NASA Astrophysics Data System (ADS)

    Barton, J.

    2009-07-01

    The proceedings contain the papers presented at the 7th International Conference on Modern Practice in Stress and Vibration Analysis. The collection of papers represents the range of activities that are carried out to understand the functionality of engineering systems and structures through stress/strain based evaluation and dynamic response. The scope is broad and covers theoretical studies, modelling and experimental evaluations. Many of the papers cover integration techniques and approaches to better understanding of system performance and failure. All of the papers have been peer reviewed by at least two experts and represent the state of the art of research in this area. The conference is the seventh in the series, following on from previous conferences in Bath, Glasgow, Nottingham, Dublin, Sheffield and Liverpool. Although based in the British Isles the conference has a truly international flavour with offerings from 22 countries. The conference is organised by the Institute of Physics Applied Mechanics Group (formerly the Stress and Vibration Group). It incorporates activities associated with the British Society for Strain Measurement including the Measurements Lecture, the EMex Exhibition and the Young Stress Analyst Competition. The organising committee is grateful for the support of all of the authors, the scientific committee and keynote speakers who played a significant role in the review process, to John Edwards who was instrumental in managing the paper review and submission process, Dawn Stewart and Claire Garland of the Institute of Physics for organising the conference, social programme and registration and Biana Gale of the British Society for Strain Measurement for organising the Exhibition. The organising committee is also grateful to the sponsors of the conference for their kind support and to the co-sponsors for distributing information on the conference. Professor Janice Barton Professor of Experimental Mechanics University of Southampton

  17. PREFACE: 7th International Conference on Modern Practice in Stress and Vibration Analysis

    NASA Astrophysics Data System (ADS)

    Dulieu-Barton, J. M.

    2009-07-01

    The proceedings contain the papers presented at the 7th International Conference on Modern Practice in Stress and Vibration Analysis. The collection of papers represents the range of activities that are carried out to understand the functionality of engineering systems and structures through stress/strain based evaluation and dynamic response. The scope is broad and covers theoretical studies, modelling and experimental evaluations. Many of the papers cover integration techniques and approaches to better understanding of system performance and failure. All of the papers have been peer reviewed by at least two experts and represent the state of the art of research in this area. The conference is the seventh in the series, following on from previous conferences in Bath, Glasgow, Nottingham, Dublin, Sheffield and Liverpool. Although based in the British Isles the conference has a truly international flavour with offerings from 22 countries. The conference is organised by the Institute of Physics Applied Mechanics Group (formerly the Stress and Vibration Group). It incorporates activities associated with the British Society for Strain Measurement including the Measurements Lecture, the EMex Exhibition and the Young Stress Analyst Competition. The organising committee is grateful for the support of all of the authors, the scientific committee and keynote speakers who played a significant role in the review process, to John Edwards who was instrumental in managing the paper review and submission process, Dawn Stewart and Claire Garland of the Institute of Physics for organising the conference, social programme and registration and Biana Gale of the British Society for Strain Measurement for organising the Exhibition. The organising committee is also grateful to the sponsors of the conference for their kind support and to the co-sponsors for distributing information on the conference. Professor Janice M Dulieu-Barton Professor of Experimental Mechanics University of

  18. Proceedings of the International Conference on Adults Learning Mathematics (ALM-7) (7th, July 6-8, 2000, Medford, Massachusetts).

    ERIC Educational Resources Information Center

    Schmitt, Mary Jane, Ed.; Safford-Ramus, Katherine, Ed.

    This volume contains the proceedings of the 7th international conference on Adults Learning Mathematics--A Research Forum held in July, 2000 in Massachusetts. It includes posters and short oral reports under these section headings: (1) Research into Practice; (2) Large- Scale Issues: Frameworks, Standards, and Assessment; (3) Theoretical…

  19. PREFACE: The 7th International Seminar on Geometry, Continua and Microstructures

    NASA Astrophysics Data System (ADS)

    Burton, David A.

    2007-04-01

    It gives me great pleasure to present the proceedings of the 7th International Seminar on Geometry, Continua and Microstructures (GCM 7). The conference took place on 25-27 September 2006 at Lancaster University and the local organisers were Robin Tucker, Tim Walton, myself and Jonathan Gratus of the Lancaster University Mathematical Physics Group. Modern field theories of mechanically and electrically responsive continua have a wealth of interesting applications in physics. Such theories provide effective macroscopic models of complex systems, such as living tissue and material with dynamical defects, that capture macroscopic consequences of microscopic phenomena. GCM is an interdisciplinary conference series, initiated by the Eringen medallist Gérard A Maugin, that brings together physicists and applied mathematicians who have interests in continuum mechanics and differential geometry and who aim to develop new and powerful methods for analysing the behaviour of complex mechanical systems. The earlier conferences in the series were held in Paris, Madrid, Mannheim, Turin, Sinaia and Belgrade. This volume addresses a variety of topics including the physics of saturated porous media, the relationship between growth in living tissue and molecular transport, the mechanics of polymer bonds, the macroscopic properties of damaged elastomers, the mechanics of carbon nanotubes, the geometry of balance systems in Continuum Thermodynamics and wave propagation in the material manifold. I would like to warmly thank the rest of the organising committee and the conference participants for making GCM 7 an enjoyable and rewarding occasion. Photographs may be found at http://www.lancs.ac.uk/depts/spc/conf/gcm7/wss/index.htm David A Burton Editor

  20. Selected papers from the 7th International Conference on Microtechnologies in Medicine and Biology (MMB 2013)

    NASA Astrophysics Data System (ADS)

    Meng, Ellis; Takayama, Shuichi

    2014-03-01

    In this special section of Journal of Micromechanics and Microengineering are a collection of the best microengineering papers presented at the 7th International Conference on Microtechnologies in Medicine and Biology (MMB 2013) which took place in the seaside town of Marina del Rey, California, USA on 10-12 April, 2013. During the 3-day conference, participants enjoyed talks from 6 invited keynote speakers and 125 flash oral/poster presentations. The MMB conference is a biennial meeting with the primary purpose of fostering interactions between biologists and medical researchers, clinicians, chemists, physicists and engineers to enhance and strengthen the potential microtechnologies that will revolutionize the fields of medicine and biological sciences. The conference possesses a unique format where all poster presenters provide a brief 60 s oral presentation highlighting their research. This format was devised to provide training and exposure for young researchers, especially PhD students and postdocs, in the field and stimulate interdisciplinary exchanges. Therefore, MMB provides an intimate intellectual venue the facilitate discussions and collaborations to advance new research tools and technologies for medicine and biological sciences. The MMB conference series was co-founded by Professor David Beebe (University of Wisconsin—Madison) and Professor André Dittmar (University of Lyon) and was the first international meeting to provide a forum focusing on emerging applications of microtechnologies to unmet needs in medicine and biology. The series was held for the first time in 2000, in Lyon, France and followed by Madison, USA (2002), Oahu Island in Hawaii, USA (2005), Okinawa, Japan (2006), Québec City, Canada (2009), Lucerne, Switzerland (2011), and Marina del Rey, USA (2013). The next conference will be held in Seoul, Korea in 2015. This collection of articles highlights recent progress in microtechnologies with medical and biological applications. We are

  1. PREFACE: 7th International Conference on Applications of Physics in Financial Analysis

    NASA Astrophysics Data System (ADS)

    Takayasu, M.; Watanabe, T.; Ikeda, Y.; Takayasu, H.

    2010-04-01

    This volume contains contributed papers from the 7th international conference on 'Applications of Physics in Financial Analysis (APFA)' held at Tokyo on 1-5 March 2009. The conference was organized jointly by Tokyo Institute of Technology and Hitotsubashi University with support from the Research Institute of Economy, Trade, and Industry (RIETI), Physical Society of Japan, Japanese Economic Association, Information Processing Society of Japan, Japanese Society for Artificial Intelligence, and Japan Association for Evolutionary Economics. The first APFA conference (APFA1) was held in 1999 at Dublin, followed by APFA2 at Liege in 2000, APFA3 at London in 2001, APFA4 at Warsaw in 2003, APFA5 at Torino in 2006, and APFA6 at Lisbon in 2007. The 7th APFA conference, which is the first meeting held outside Europe, was attended by 223 researchers in physics and economics from 23 countries world-wide. In keeping with past APFA conferences, we paid special attention to issues in financial markets, which turned out to be very timely. The conference was held in March 2009, in the middle of the global financial crisis that originally started in the US and spread quickly to every corner of the world. The topic of the conference is 'New Approaches to the Analysis of Large Scale Business and Economic data'. The rapid development of information and communication technology has enabled financial/non-financial firms to keep detailed records of their business activities in the form of, for example, tick-by-tick data in financial markets, point-of-sale (POS) data on individual household's purchasing activity, and interfirm network data describing relationships among firms in terms of suppliers/customers transactions and ownerships. This growth in the scope and amount of business data available to researchers has led to a far-reaching expansion in research possibilities. Researchers not only in social sciences but also in physics, mathematics, and information sciences have recently

  2. Proceedings of the Seventh International Conference on Educational Data Mining (EDM) (7th, London, United Kingdom, July 4-7, 2014)

    ERIC Educational Resources Information Center

    Stamper, John, Ed.; Pardos, Zachary, Ed.; Mavrikis, Manolis, Ed.; McLaren, Bruce M., Ed.

    2014-01-01

    The 7th International Conference on Education Data Mining held on July 4th-7th, 2014, at the Institute of Education, London, UK is the leading international forum for high-quality research that mines large data sets in order to answer educational research questions that shed light on the learning process. These data sets may come from the traces…

  3. PREFACE: 7th International Conference on 3D Radiation Dosimetry (IC3DDose)

    NASA Astrophysics Data System (ADS)

    Thwaites, David; Baldock, Clive

    2013-06-01

    IC3DDose 2013, the 7th International Conference on 3D Radiation Dosimetry held in Sydney, Australia from 4-8 November 2012, grew out of the DosGel series, which began as DosGel99, the 1st International Workshop on Radiation Therapy Gel Dosimetry in Lexington, Kentucky. Since 1999 subsequent DoSGel conferences were held in Brisbane, Australia (2001), Ghent, Belgium (2004), Sherbrooke, Canada (2006) and Crete, Greece (2008). In 2010 the conference was held on Hilton Head Island, South Carolina and underwent a name-change to IC3DDose. The aim of the first workshop was to bring together individuals, both researchers and users, with an interest in 3D radiation dosimetry techniques, with a mix of presentations from basic science to clinical applications, which has remained an objective for all of the meetings. One rationale of DosGel99 was stated as supporting the increasing clinical implementation of gel dosimetry, as the technique appeared, at that time, to be leaving the laboratories of gel dosimetry enthusiasts and entering clinical practice. Clearly by labelling the first workshop as the 1st, there was a vision of a continuing series, which has been fulfilled. On the other hand, the expectation of widespread clinical use of gel dosimetry has perhaps not been what was hoped for and anticipated. Nevertheless the rapidly increasing demand for advanced high-precision 3D radiotherapy technology and techniques has continued apace. The need for practical and accurate 3D dosimetry methods for development and quality assurance has only increased. By the 6th meeting, held in South Carolina in 2010, the Conference Scientific Committee recognised the wider developments in 3D systems and methods and decided to widen the scope, whilst keeping the same span from basic science to applications. This was signalled by a change of name from 'Dosgel' to 'IC3DDose', a name that has continued to this latest conference. The conference objectives were: to enhance the quality and accuracy of

  4. PATRAM '83: 7th International Symposium on Packaging and Transportation of Radioactive Materials, summaries

    NASA Astrophysics Data System (ADS)

    Papers were presented at the following sessions: international regulations; materials, fracture toughness of ferritic steels; risk analysis techniques; storage in packagings; packaging design considerations; monolithic cast iron casks; risk analysis; facility/transportation system interface; research and development programs; UF6 packagings; national regulations; transportation operations and traffic; containment, seals, and leakage; radiation risk experience; emergency response; structural modeling and testing; transportation system planning; institutional issues and public response; packaging systems; thermal analysis and testing; systems analysis; structural analyses; quality assurance; packaging and transportation systems; physical protection; criticality and shielding; transportation operations and experience; standards; shock absorber technology; and information and training for regulatory compliance. Individual summaries are title listed.

  5. PREFACE: 7th International Conference on Quantum Theory and Symmetries (QTS7)

    NASA Astrophysics Data System (ADS)

    Burdík, Čestmír; Navrátil, Ondřej; Pošta, Severin; Schnabl, Martin; Šnobl, Libor

    2012-02-01

    The Seventh International Conference Quantum Theory and Symmetries (QTS7), organized by the Departments of Mathematics and Physics, Faculty of Nuclear Sciences and Physical Engineering at the Czech Technical University in Prague, the Bogoliubov Laboratory of Theoretical Physics of the Joint Institute for Nuclear Research and the Institute of Physics at the Academy of Sciences of the Czech Republic, belongs to a successful series of conferences which began at Goslar, Germany in 1999. More recent QTS conferences were held in Poland, Bulgaria, USA and Spain. QTS7 gathered around 300 scientists from all over the world. 136 of the plenary lectures and contributions presented at QTS7 are published in this issue of Journal of Physics: Conference Series. We acknowledge support from the Commission for co-operation with JINR Dubna and grant LA-08002 from the Ministry of Education of the Czech Republic. Čestmír Burdík Chairman Local Organizing Committee

  6. PREFACE: 7th International Symposium on Large TPCs for Low-Energy Rare Event Detection

    NASA Astrophysics Data System (ADS)

    Colas, P.; Giomataris, I.; Irastorza, I.; Patzak, Th

    2015-11-01

    The seventh "International Symposium on Large TPCs for Low-Energy Rare Event Detection", took place in Paris between the 15th and 17th of December 2014 at the Institute of Astroparticle Physics (APC) campus - Paris Diderot University. As usual the conference was organized during the week before Christmas, which seems to be convenient for most of the people and occurs every two years with almost 120 participants attending. Many people contributed to the success of the conference, but the organizers would particularly like to thank the management of APC for providing the nice Buffon auditorium and infrastructure. We also acknowledge the valuable support of DSM-Irfu and the University of Zaragoza. The scientific program consisted of plenary sessions including the following topics with theoretical and experimental lectures: • Low energy neutrino physics • Neutrinoless double beta decay process • Dark matter searches • Axion and especially solar axion searches • Space experiments and gamma-ray polarimetry • New detector R&D and future experiments

  7. PREFACE: 7th International Workshop DICE2014 Spacetime - Matter - Quantum Mechanics

    NASA Astrophysics Data System (ADS)

    Elze, H. T.; Diósi, L.; Fronzoni, L.; Halliwell, J. J.; Kiefer, C.; Prati, E.; Vitiello, G.

    2015-07-01

    Presented in this volume are the Invited Lectures and the Contributed Papers of the Seventh International Workshop on Decoherence, Information, Complexity and Entropy - DICE 2014, held at Castello Pasquini, Castiglioncello (Tuscany), September 15-19, 2014. These proceedings are intended to reflect the lively exchange of ideas during the meeting for the interested public and the wider scientific community, as well as to provide a document of the scientific works presented. The number of participants has continued to grow, which may correspond to an increasing attraction, if not need, of such conference: Our very intention has always been to bring together leading researchers, advanced students, and renowned scholars from various areas, in order to stimulate new ideas and their exchange across the borders of specialization. In this way, the series of meetings successfully continued from the beginning with DICE 2002, followed by DICE 2004, DICE 2006, DICE 2008, DICE 2010, and DICE 2012. This time, DICE 2014 brought together more than 120 participants representing more than 30 countries. It has been a great honour and inspiration that we had with us Nobel Prize laureate Gerard 't Hooft (Utrecht - Keynote Lecture ''The Cellular Automaton Interpretation and Bell's Theorem''), Fields Medal winner Alain Connes (Paris - Keynote Lecture ''Quanta of geometry''), Professor Avshalom Elitzur (Rehovot - Keynote Lecture ''Voices of silence, novelties of noise: on some quantum hairsplitting methods with nontrivial consequences'', in this volume) and Professor Mario Rasetti (Torino - Keynote Lecture ''The topological field theory of data: a possible new venue for data mining'', in this volume). The opening Keynote Lecture ''History of electroweak symmetry breaking'' was presented by Sir Tom Kibble (London), co-discoverer of the Higgs mechanism, Sakurai Prize laureate and winner of, i.a., Dirac and Einstein Medals.

  8. 7th International Conference on Excitonic Processes in Condensed Matter (EXCON'06) Winston-Salem, NC, USA, 26-30 June 2006

    NASA Astrophysics Data System (ADS)

    Petelenz, P.; Schreiber, M.

    2006-10-01

    This conference report is meant to offer an authoritative view on a recently held scientific meeting rather than a comprehensive list of the conference presentations. We tried to describe what we feel were the most interesting contributions.The full Proceedings of the 7th International Conference on Excitonic Processes in Condensed Matter (EXCON'06) shall be published in phys. stat. sol. (b) and phys. stat. sol. (c) in November 2006.

  9. PREFACE: NC-AFM 2004: Proceedings of the 7th International Conference on Non-contact Atomic Force Microscopy

    NASA Astrophysics Data System (ADS)

    Schwarz, Udo

    2005-03-01

    With the ongoing miniaturization of devices and controlled nanostructuring of materials, the importance of atomic-scale information on surfaces and surface properties is growing continuously. The astonishing progress in nanoscience and nanotechnology that took place during the last two decades was in many ways related to recent progress in high-resolution imaging techniques such as scanning tunnelling microscopy and transmission electron microscopy. Since the mid-1990s, non-contact atomic force microscopy (NC-AFM) performed in ultrahigh vacuum has evolved as an alternative technique that achieves atomic resolution, but without the restriction to conducting surfaces of the previously established techniques. Advances of the rapidly developing field of NC-AFM are discussed at annual conferences as part of a series that started in 1998 in Osaka, Japan. This special issue of Nanotechnology is a compilation of original work presented at the 7th International Conference on Non-contact Atomic Force Microscopy that took place in Seattle, USA, 12-15 September 2004. Over the years, the conference grew in size and scope. Atomic resolution imaging of oxides and semiconductors remains an issue. Noticeable new developments have been presented in this regard such as, e.g., the demonstrated ability to manipulate individual atoms. Additionally, the investigation of individual molecules, clusters, and organic materials gains more and more attention. In this context, considerable effort is undertaken to transfer the NC-AFM principle based on frequency modulation to applications in air and liquids with the goal of enabling high-resolution surface studies of biological material in native environments, as well as to reduce the experimental complexity, which so far involves the availability of (costly) vacuum systems. Force spectroscopy methods continue to be improved and are applied to topics such as the imaging of the three-dimensional force field as a function of the distance with

  10. Selected papers from the 7th International Conference on Biomimetics, Artificial Muscles and Nano-bio (BAMN2013)

    NASA Astrophysics Data System (ADS)

    Shahinpoor, Mohsen; Oh, Ilkwon

    2014-07-01

    The 7th International Congress on Biomimetics, Artificial Muscles and Nano-Bio was held on the magnificent and beautiful Jeju Island in Korea on 26-30 August 2013. In June 2007, the volcanic island and lava tube cave systems were designated as UNESCO World Natural Heritage Sites for their natural beauty and unique geographical values. The aim of the congress was to offer high-level lectures, extensive discussions and communications covering the state-of-the-art on biomimetics, artificial muscles, and nano-bio technologies providing an overview of their potential applications in the industrial, biomedical, scientific and robotic fields. This conference provided a necessary platform for an ongoing dialogue between researchers from different areas (chemistry, physics, biology, medicine, engineering, robotics, etc) within biomimetics, artificial muscle and nano-bio technologies. This special issue of Smart Materials and Structures is devoted to a selected number of research papers that were presented at BAMN2013. Of the 400 or so papers and over 220 posters presented at this international congress, 15 papers were finally received, reviewed and accepted for this special issue, following the regular peer review procedures of the journal. The special issue covers polymeric artificial muscles, electroactive polymers, multifunctional nanocomposites, and their applications. In particular, electromechanical performance and other characteristics of ionic polymer-metal composites (IPMCs) fabricated with various commercially available ion exchange membranes are discussed. Additionally, the control of free-edge interlaminar stresses in composite laminates using piezoelectric actuators is elaborated on. Further, the electrode effects of a cellulose-based electroactive paper energy harvester are described. Next, a flexible tactile-feedback touch screen using transparent ferroelectric polymer film vibrators is discussed. A broad coverage of bio-applications of IPMC transducers is

  11. Proceedings of the 7th International Meeting on Nuclear Reactor Thermal-Hydraulics NURETH-7. Volume 1, Sessions 1-5

    SciTech Connect

    Block, R.C.; Feiner, F.

    1995-09-01

    This document, Volume 1, includes papers presented at the 7th International Meeting on Nuclear Reactor Thermal-Hydraulics (NURETH-7) September 10--15, 1995 at Saratoga Springs, N.Y. The following subjects are discussed: Progress in analytical and experimental work on the fundamentals of nuclear thermal-hydraulics, the development of advanced mathematical and numerical methods, and the application of advancements in the field in the development of novel reactor concepts. Also combined issues of thermal-hydraulics and reactor/power-plant safety, core neutronics and/or radiation. Selected papers are indexed separately for inclusion in the Energy Science and Technology Database.

  12. Proceedings of the 5th International LISA Symposium and the 38th ESLAB Symposium, ESTEC, Noordwijk, The Netherlands, 12-15 July 2004

    NASA Astrophysics Data System (ADS)

    Jennrich, Oliver

    2005-05-01

    In its 10th year, the International LISA Symposium of 2004 was the first to be organized by ESA. After the first Symposium at the Rutherford Appleton Laboratory in 1996, and subsequent Symposia at Caltech (1998), the Albert Einstein Institute in Golm (2000) and Penn State University (2002), ESA's European Space and Technology Centre (ESTEC) is proud to have hosted the 5th International LISA Symposium in 2004 in conjunction with the 38th ESLAB Symposium. During these 10 years, we have seen the technology required for such ambitious space missions as LISA and LISA Pathfinder developing and maturing to a point where flightlevel hardware can be produced and tested. The technology demonstrator LISA Pathfinder has become a mission well established in the ESA programme and has entered its project implementation phase; the LISA mission is in the formulation phase. At the same time, the preparations for LISA data analysis and first activities on data archives and LISA simulators have begun, indicating that LISA is regarded as more than just a mission far in the future. The astrophysics of the sources of gravitational waves is emerging as a rapidly growing field that will become even more important in the coming years, when the focus of the activities on LISA and LISA Pathfinder will shift from making the missions possible to deriving scientific results from the data. The 5th International LISA Symposium had presentations on all of the above topics, from the technology of LISA and LISA Pathfinder, LISA data analysis, and modelling and simulation, to the astrophysics of the sources. The programme included an overview of the activities at the ground-based detectors, with which LISA shares not only a common technological heritage but also the prospect of detecting gravitational waves in the next 10 years. Such a conference would not be possible without the help of many people, not least the Scientific Organizing Committee, and the local organization, provided by ESA

  13. The First Year Experience. Conference Proceedings of the International Conference (7th, Dublin, Ireland, July 18-22, 1994).

    ERIC Educational Resources Information Center

    South Carolina Univ., Columbia. Center for the Study of the Freshman Year Experience.

    These proceedings contain 68 author-prepared abstracts of presentations given at the Seventh International Conference on the First-Year Experience, a 5-day conference that focused on the foundations for improving the undergraduate experience. The majority of the one- to two-page abstracts report on specific programs undertaken by colleges or…

  14. Education Across Cultures: Domestic and International Perspectives. Proceedings of the Annual Colloquium (7th, Pittsburgh, Pennsylvania, March 28, 1981).

    ERIC Educational Resources Information Center

    Pittsburgh Univ., PA. Council of Graduate Students in Education.

    The Council for Graduate Students in Education's Seventh Annual Colloquium was held on March 28, 1981, on the theme "Education Across Cultures: Domestic and International Perspectives." Papers presented include: "Symbolic Strategies in the Organization of Ethnic Study Programs" (Julian E. Abuso); "The Prospective…

  15. EDITORIAL: Proceedings of the 8th International LISA Symposium, Stanford University, California, USA, 28 June-2 July 2010 Proceedings of the 8th International LISA Symposium, Stanford University, California, USA, 28 June-2 July 2010

    NASA Astrophysics Data System (ADS)

    Buchman, Sasha; Sun, Ke-Xun

    2011-05-01

    The international research community interested in the Laser Interferometric Space Antenna (LISA) program meets every two years to exchange scientific and technical information. From 28 June-2 July 2010, Stanford University hosted the 8th International LISA Symposium. The symposium was held on the campus of the SLAC National Accelerator Laboratory. Many of the foremost scientific and technological researchers in LISA and gravitational wave theory and detection presented their work and ideas. Over one hundred engineers and graduate students attended the meeting. The leadership from NASA and ESA research centers and programs joined the symposium. A total of 280 delegates participated in the 8th LISA Symposium, and enjoyed the scientific and social programs. The scientific program included 46 invited plenary lectures, 44 parallel talks, and 77 posters, totaling 167 presentations. The one-slide introduction presentation of the posters is a new format in this symposium and allowed graduate students the opportunity to talk in front of a large audience of scientists. The topics covered included LISA Science, LISA Interferometry, LISA PathFinder (LPF), LISA and LPF Data Analysis, Astrophysics, Numerical Relativity, Gravitational Wave Theory, GRS Technologies, Other Space Programs, and Ground Detectors. Large gravitational wave detection efforts, DECIGO, and LIGO were presented, as well as a number of other fundamental physics space experiments, with GP-B and STEP being examples. A public evening lecture was also presented at the symposium. Professor Bernard Schutz from the Albert Einstein Institute gave a general audience, multimedia presentation on `Gravitational waves: Listening to the music of spheres'. For more detailed information about the symposium and many presentation files, please browse through the website: http://www.stanford.edu/group/lisasymposium The Proceedings of the 8th International LISA Symposium are jointly published by Classical and Quantum Gravity

  16. Mentoring LISA

    NASA Astrophysics Data System (ADS)

    Corbin, B. G.; Bouton, E. N.

    2010-10-01

    LISA meetings began with a core group of librarians who continued to work on planning future conferences. A Preliminary Organizing Committee (POC) was formed by this group after LISA I. Brief biographies of these early POC members, Ellen Bouton, Brenda Corbin, Marlene Cummins, and Sarah Stevens-Rayburn are given. The formation of the fundraising group Friends of LISA (FOL) is also briefly discussed.

  17. Solar particle event detected by ALTEA on board the International Space Station. The March 7th, 2012 X5.4 flare

    NASA Astrophysics Data System (ADS)

    Di Fino, Luca; Zaconte, Veronica; Stangalini, Marco; Sparvoli, Roberta; Picozza, Piergiorgio; Piazzesi, Roberto; Narici, Livio; Larosa, Marianna; Del Moro, Dario; Casolino, Marco; Berrilli, Francesco; Scardigli, Stefano

    2014-05-01

    Context. Solar activity poses substantial risk for astronauts of the International Space Station (ISS) both on board and during extravehicular activity. An accurate assessment of the charged radiation flux in space habitats is necessary to determine the risk and the specific type of radiation exposure of ISS crew members, and to develop ways to protect future crews for planetary missions, even in case of high solar activity. Aims: To reduce the present-day uncertainties about the nature and magnitude of the particle fluxes in space habitats during a solar event, it is fundamental to measure those fluxes in situ. Methods: The ALTEA (Anomalous Long Term Effects on Astronauts) experiment on board the ISS is an active detector composed of six silicon telescopes and is able to follow the dynamics of the radiation flux. During its operation in 2012 a number of flux peaks were detected in correspondence with solar events. Results: We present in this work an analysis of the ALTEA data measured during the March 7th, 2012 solar event, produced by NOAA AR11429. Conclusions: During this event, the flux was enhanced tenfold with respect to ``quiet Sun'' conditions, producing strong dose increases at high geomagnetic latitudes.

  18. LISA Pathfinder

    NASA Technical Reports Server (NTRS)

    Stebbins, Robin

    2008-01-01

    USA Pathfinder is a space mission dedicated to demonstrating technology for the Laser Interferometer Space Antenna (LISA). LISA is a joint ESA/NASA mission to detect low-frequency gravitational waves on the 0.0001 to 0.1 Hz frequency band. LISA is expected to observe 100's of merging massive black hole binaries out z-15, tens of thousands of close compact binary systems in the Milky Way, merging intermediate-mass black hole binaries, tens of stellar-mass black holes falling into supermassive black holes in galactic centers, and possibly other exotic sources. Several critical LISA technologies have not been demonstrated at the requisite level of performance. In spaceflight, and some fight hardware cannot be tested in a 1-g environment. Hence, the LISA Pathfinder mission is being implemented to demonstrate these critical LISA technologies in a relevant flight environment. LISA Pathfinder mimics one arm of the LISA constellation by shrinking the 5-million-kilometer armlength down to a few tens of centimeters. The experimental concept is to measure the relative separation between two test masses nominally following their own geodesics, and thereby determine the relative residual acceleration between them near 1 mHz, about a decade above the lowest frequency required by LISA. To implement such a concept, disturbances on the test masses must be kept very small by many design features, but chiefly by "drag-free" flight. A drag-free spacecraft follows a free-falling test mass which it encloses, but has no mechanical connection to. The spacecraft senses it's orientation and separation with respect to the proof mass, and its propulsion system is commanded to keep the spacecraft centered about the test mass. Thus, the spacecraft shields the test mass from most external influences, and minimizes the effect of force gradients arising from the spacecraft, and acting on the test mass. LISA Pathfinder will compare the geodesic of one test mass against that of the other. Only a

  19. EDITORIAL: The 7th International Workshop on Micro and Nanotechnologies for Power Generation and Energy Conversion Applications (PowerMEMS 2007)

    NASA Astrophysics Data System (ADS)

    Hebling, C.; Woias, P.

    2008-10-01

    This special issue of Journal of Micromechanics and Microengineering (JMM) contains a selection of papers from the 7th International Workshop on Micro and Nanotechnologies for Power Generation and Energy Conversion (PowerMEMS 2007). The workshop was held in Freiburg, Germany on 27-29 November 2007 under the joint organization of the Fraunhofer Institute for Solar Energy Systems (FhG-ISE), Freiburg and the Department of Microsystems Engineering (IMTEK) of the Albert-Ludwig-University of Freiburg. PowerMEMS 2007 continues a series of workshops initiated in 2000 in Japan to create an annual discussion forum in the emerging field of micro energy technology. With a single exception in 2001, the workshop has continued as an annual meeting ever since, with a continuous increase in the number of presentations and participants. The program of PowerMEMS 2007 was composed of 2 invited talks, 25 oral talks and 61 poster presentations. From these 88 presentations 16 have been selected for this special issue. It was at the end of 1959 when the Caltech physicist Richard Feynman gave his famous lecture entitled 'There Is Plenty of Room at the Bottom' in which he discussed the possibilities of miniaturization for both storage capacity ('Encyclopaedia Britannica on the head of a pin') as well as micro machining ('rearranging the atoms'), although there were absolutely no technological possibilities in sight for an adequate realization of such ideas. Now, nearly 50 years later, we not only have incredible knowledge about the nanoworld, but even more we are now able to generate microelectromechanical devices which, next to their electronic properties, can integrate physical and analytical functions. Today, Feynman might easily have added a second lecture entitled 'There is Plenty of Energy at the Bottom'. Micro energy technology has seen a tremendous rise in MEMS and material sciences and is regarded today as one of their hot topics. Also, there are more and more companies in this

  20. Rightsizing LISA

    NASA Technical Reports Server (NTRS)

    Stebbins, Robin T.

    2008-01-01

    The LISA science requirements and conceptual design have been fairly stable for over a decade. In the interest of reducing costs, the LISA Project at NASA has looked for simplifications of the architecture, at downsizing of subsystems, and at descopes of the entire mission. This is a natural activity of the formulation phase, and one that is particularly timely in the current NASA budgetary context. There is, and will continue to be, enormous pressure for cost reduction from both ESA and NASA, reviewers and the broader research community. Here, we review the rationale for the baseline architecture. and report recent efforts to find simplifications and other reductions that might lead to savings. A few possible simplifications have been found in the LISA baseline architecture. In the interest of exploring cost sensitivity, one moderate and one aggressive descope have been evaluated; the cost savings are modest and the loss of science is not.

  1. Rightsizing LISA

    NASA Technical Reports Server (NTRS)

    Stebbins, Robin T.

    2009-01-01

    The LISA science requirements and conceptual design have been fairly stable for over a decade. In the interest of reducing costs, the LISA Project at NASA has looked for simplifications of the architecture, at downsizing of subsystems, and at descopes of the entire mission. This is a natural activity of the formulation phase, and one that is particularly timely in the current NASA budgetary context. There is, and will continue to be, enormous pressure for cost reduction from both ESA and NASA, reviewers and the broader research community. Here, the rationale for the baseline architecture is reviewed, and recent efforts to find simplifications and other reductions that might lead to savings are reported. A few possible simplifications have been found in the LISA baseline architecture. In the interest of exploring cost sensitivity, one moderate and one aggressive descope have been evaluated; the cost savings are modest and the loss of science is not.

  2. PREFACE PASREG: The 7th International Workshop on the Processing and Applications of Superconducting (RE)BCO Large Grain Materials (Washington DC, 29-31 July 2010) PASREG: The 7th International Workshop on the Processing and Applications of Superconducting (RE)BCO Large Grain Materials (Washington DC, 29-31 July 2010)

    NASA Astrophysics Data System (ADS)

    Freyhardt, Herbert; Cardwell, David; Strasik, Mike

    2010-12-01

    Large grain, (RE)BCO bulk superconductors fabricated by top seeded melt growth (TSMG) are able to generate large magnetic fields compared to conventional, iron-based permanent magnets. Following 20 years of development, these materials are now beginning to realize their considerable potential for a variety of engineering applications such as magnetic separators, flywheel energy storage and magnetic bearings. MgB2 has also continued to emerge as a potentially important bulk superconducting material for engineering applications below 20 K due to its lack of granularity and the ease with which complex shapes of this material can be fabricated. This issue of Superconductor Science and Technology contains a selection of papers presented at the 7th International Workshop on the Processing and Applications of Superconducting (RE)BCO Large Grain Materials, including MgB2, held 29th-31sy July 2010 at the Omni Shoreham Hotel, Washington DC, USA, to report progress made in this field in the previous three year period. The workshop followed those held previously in Cambridge, UK (1997), Morioka, Japan (1999), Seattle, USA (2001), Jena, Germany (2003), Tokyo, Japan (2005) and again in Cambridge, UK (2007). The scope of the seventh PASREG workshop was extended to include processing and characterization aspects of the broader spectrum of bulk high temperature superconducting (HTS) materials, including melt-cast Bi-HTS and bulk MgB2, recent developments in the field and innovative applications of bulk HTS. A total of 38 papers were presented at this workshop, of which 30 were presented in oral form and 8 were presented as posters. The organizers wish to acknowledge the efforts of Sue Butler of the University of Houston for her local organization of the workshop. The eighth PASREG workshop will be held in Taiwan in the summer of 2012.

  3. LISA Pathfinder and eLISA news

    NASA Technical Reports Server (NTRS)

    Thorpe, James Ira; Mueller, Guido

    2014-01-01

    Two important gatherings of the space-based gravitational-wave detector community were held in Zurich, Switzerland this past March. The first was a meeting of the Science Working Team for LISA Pathfinder (LPF), a dedicated technology demonstrator mission for a future LISA-like gravitational wave observatory. LPF is entering an extremely exciting phase with launch less than 15 months away. All flight components for both the European science payload, known as the LISA Technology Package (LTP), and the NASA science payload, known as the Space Technology 7 Disturbance Reduction System (ST7-DRS), have been delivered and are undergoing integration. The final flight component for the spacecraft bus, a cold-gas thruster based on the successful GAIA design, will be delivered later this year. Current focus is on completing integration of the science payload (see Figures 1 and 2) and preparation for operations and data analysis. After a launch in Summer 2015, LPF will take approximately 90 days to reach its operational orbit around the Earth-Sun Lagrange point (L1), where it will begin science operations. After 90 days of LTP operations followed by 90 days of DRS operations, LPF will have completed its prime mission of paving the way for a space-based observatory of gravitational waves in the milliHertz band. Immediately following the meeting of the LPF team, the eLISA consortium held its third progress meeting. The consortium (www.elisascience.org) is the organizing body of the European space-based gravitational-wave community, and it was responsible for the "The Gravitational Universe" whitepaper that resulted in the November 2013 election of a gravitational-wave science theme for ESA's Cosmic Visions L3 opportunity. In preparation for an L3 mission concept call, which is expected later this decade, and for launch in the mid 2030s, the eLISA consortium members are coordinating technology development and mission study activities which will build on the LPF results. The final

  4. CERT tribal internship program. Final intern report: D`Lisa Penney, 1994

    SciTech Connect

    1998-09-01

    The purpose of this intern`s project was to: education the Nez Perce people of the Hanford situation; begin researching into past and present health effects from the Hanford site; and inform and educate the Nez Perce people of the Hanford site and past exposures. The specific objectives were to begin researching the history of Nez Perce people and Hanford; create an understanding for the importance of this research; define the radiation and risks and how they occur; inform the Nez Perce people of the issue; and write the paper so it is easy to understand. This intern report contains a copy of the final paper written for the Nez Perce people. Because the dose reconstruction for Hanford is not complete, the health effects section is informative, but not definitive.

  5. Museums and the Web 2003: Selected Papers from an International Conference (7th, Charlotte, North Carolina, March 19-22, 2003).

    ERIC Educational Resources Information Center

    Bearman, David, Ed.; Trant, Jennifer, Ed.

    This is the proceedings of the seventh annual Museums and the Web conference which took place March 19-22, 2003. MW2003 was the premier international venue to review the state of the Web in arts, culture, and heritage. The formal program consisted of two plenary sessions, eighteen parallel sessions, 35 museum project demonstrations, dozens of…

  6. "Relating in a Global Community." Proceedings of the International Conference on Counseling in the 21st Century (7th, Sydney, Australia, December 29-31, 1998.)

    ERIC Educational Resources Information Center

    1998

    The papers presented at this conference consider the many roles counselors play in people's lives throughout their lifespan. The age of technology has aided the practice of counseling in becoming international in scope, although there are different functional frameworks that exist in various political, economic, social, and value systems in world…

  7. Proceedings of N.A.Web 2001: The International North America Web-Based Learning Conference (7th, Fredericton, New Brunswick, Canada, October 13-16, 2001).

    ERIC Educational Resources Information Center

    Ellis, Allan, Ed.; Hall, Rik, Ed.; Li, Jeni, Ed.

    NAWeb 2001, the International North America Web-Based Learning Conference, focused on innovative and practical uses of the World Wide Web in teaching and learning. This proceedings contains the following papers: (1) "Roles of Parties Involved in Distance Learning" (Ahlam Al-Bassam, Peter Neubert, Ali Al-Shammari); (2) "The World…

  8. International Conference on Education in Sparsely Populated Rural Areas (7th, Golspie High School, County of Sutherland, Scotland, July 9-17, 1974). Interskola Golspie '74 Report.

    ERIC Educational Resources Information Center

    Aberdeen Coll. of Education (Scotland).

    Papers from a conference series initiated in the Aberdeen College of Education in 1968 and recently held in Golspie, Scotland (July 1974), address policy oriented recommendations relative to rural education. This conference report is intended to serve as a useful source of ideas; as background information on international rural educational…

  9. Heliospheric influences on LISA

    NASA Astrophysics Data System (ADS)

    Grimani, C.; Fabi, M.; Finetti, N.; Tombolato, D.; Marconi, L.; Stanga, R.; Lobo, A.; Chmeissani, M.; Puigdengoles, C.

    2009-05-01

    Laser interferometer space antenna (LISA) is the first interferometer devoted to the detection of low frequency gravitational waves in space. Control of the environment and the study of the effects of energetic particles traversing the LISA apparatus are mandatory for this experiment to be fully successful. Telescopes for solar and cosmic-ray particle monitoring will be placed on board LISA and its precursor mission LISA Pathfinder (LISA-PF). In particular, proton, helium and electron detection is recommended on LISA. In this paper, we report expected incident galactic proton and helium fluxes at the time of LISA and LISA-PF missions. The number of solar events with the fluence ranging between 106 and 1011 protons cm-2 above 30 MeV occurring during the LISA missions is estimated as well. Finally, we discuss the importance of electron detection on LISA to forecast upcoming solar energetic protons.

  10. 7(th) International Immunoglobulin Conference: Poster presentations.

    PubMed

    Warnatz, K; Ballow, M; Stangel, M; Bril, V

    2014-12-01

    Immunoglobulin (Ig) therapy is the mainstay of treatment for primary antibody deficiency disorders and has proved to be efficacious in specific autoimmune and inflammatory diseases. Additionally, due to the role of Ig in complement activation, it is being used increasingly in solid organ transplantation. Furthermore, Ig is the primary or secondary treatment in some immune-mediated neuropathies such as chronic inflammatory demyelinating polyneuropathy (CIDP) or multifocal motor neuropathy (MMN). This session discusses trends of Ig use in Europe, proposed mechanisms of action, adverse effects and the potential role of Ig therapy in transplantation. Dr Šedivá reported that Ig therapy is available in all European countries, although dosing is not always optimal, due partly to reimbursement plans. Subcutaneous immunoglobulin (SCIg) has become increasingly accessible in recent years; however, the chosen route of administration still varies widely between countries. Dr Berger's presentation on optimization of Ig therapy in neuropathies, and Dr Rojavin's report on a pharmacometric model to determine the serum IgG levels achieved by different dosing regimens in primary antibody deficiency (PAD) patients, led to the challenging concept of using individualized dosing strategies. Dr Klehmet reported on the potential benefit of using antigen-specific T cell responses as a biomarker of IVIg responsiveness in CIDP patients, while Dr von Gunten provided an insight into the mechanisms of action of Ig preparations, suggesting that the immunoregulatory effects of IgG may be mediated by IgG antibodies against glycans. Dr Basta reported on the potential thrombogenic adverse effects associated with Ig therapy. Although these adverse events are rare, further studies are needed to clarify the relationship between Ig replacement and immunomodulatory therapy and these adverse reactions. In transplantation, Dr Carbone described that prophylactic IVIg treatment was found to decrease the incidence of severe infection in IgG hypogammaglobulinaemia patients undergoing heart transplantations. Furthermore, Dr Clatworthy reported that inactivating polymorphisms in the inhibitory receptor FcγRIIB do not impact upon kidney allograft survival.

  11. 7th International Immunoglobulin Conference: Poster Presentations

    PubMed Central

    Warnatz, K; Ballow, M; Stangel, M; Bril, V

    2014-01-01

    Immunoglobulin (Ig) therapy is the mainstay of treatment for primary antibody deficiency disorders and has proved to be efficacious in specific autoimmune and inflammatory diseases. Additionally, due to the role of Ig in complement activation, it is being used increasingly in solid organ transplantation. Furthermore, Ig is the primary or secondary treatment in some immune-mediated neuropathies such as chronic inflammatory demyelinating polyneuropathy (CIDP) or multifocal motor neuropathy (MMN). This session discusses trends of Ig use in Europe, proposed mechanisms of action, adverse effects and the potential role of Ig therapy in transplantation. Dr Šedivá reported that Ig therapy is available in all European countries, although dosing is not always optimal, due partly to reimbursement plans. Subcutaneous immunoglobulin (SCIg) has become increasingly accessible in recent years; however, the chosen route of administration still varies widely between countries. Dr Berger's presentation on optimization of Ig therapy in neuropathies, and Dr Rojavin's report on a pharmacometric model to determine the serum IgG levels achieved by different dosing regimens in primary antibody deficiency (PAD) patients, led to the challenging concept of using individualized dosing strategies. Dr Klehmet reported on the potential benefit of using antigen-specific T cell responses as a biomarker of IVIg responsiveness in CIDP patients, while Dr von Gunten provided an insight into the mechanisms of action of Ig preparations, suggesting that the immunoregulatory effects of IgG may be mediated by IgG antibodies against glycans. Dr Basta reported on the potential thrombogenic adverse effects associated with Ig therapy. Although these adverse events are rare, further studies are needed to clarify the relationship between Ig replacement and immunomodulatory therapy and these adverse reactions. In transplantation, Dr Carbone described that prophylactic IVIg treatment was found to decrease the incidence of severe infection in IgG hypogammaglobulinaemia patients undergoing heart transplantations. Furthermore, Dr Clatworthy reported that inactivating polymorphisms in the inhibitory receptor FcγRIIB do not impact upon kidney allograft survival. PMID:25546796

  12. 7th International Immunoglobulin Conference: Immunodeficiencies

    PubMed Central

    Schmidt, R E; Ochs, H D

    2014-01-01

    Most primary immunodeficiency disorders (PID) are the result of single gene defects. Based on this fact, more than 240 different entities have been identified. Those PIDs with predominant antibody deficiency are treated with immunoglobulin (Ig) replacement therapy. This review focuses on the diagnosis, clinical characteristics and treatment of patients suffering from PID, or secondary immunodeficiency disorders (SID) caused, for instance, by irradiation, immunosuppressive drugs or thymectomy. Common variable immunodeficiency (CVID) is the most commonly diagnosed and least understood form of PID, with a heterogeneous range of symptoms and genotypes, requiring individualized treatment plans. This includes adjusting the dose and treatment interval, administrating Ig by intravenous or subcutaneous injection by either pump or push, and finally deciding which treatment options are best for a given patient. Ig therapy can also be used to treat immunodeficiencies resulting from lymphoproliferative and autoimmune diseases or immunosuppression following organ transplantation; however, there is an urgent need for research in this field. Accurate and early diagnosis of PID is important to ensure that optimal treatment is started early to maintain the patient's health. Detailed patient registries have been established to increase awareness of PID, as well as provide a valuable resource for further research. PMID:25546741

  13. 7th International Immunoglobulin Conference: Immunodeficiencies

    PubMed Central

    Schmidt, R E; Ochs, H D

    2014-01-01

    Awareness of the challenges involved in diagnosing and treating a heterogeneous group of immunodeficiency disorders is growing. The improvements in neonatal screening offer new methods to ensure that primary immunodeficiencies (PIDs) are diagnosed as early as possible, enabling accurate treatment and the prevention of life-threatening infections and other complications. Additionally, the need to individualize patient therapy in order to optimize both clinical outcomes and quality-of-life is obvious and is exemplified by the ability to switch between intravenous and subcutaneous immunoglobulin administration offering flexible treatment regimens. However, further research is crucial in order to determine the optimal treatment for secondary immunodeficiencies, and to gain greater understanding of the underlying causes of PIDs, including common variable immunodeficiency. The information relating to the growth of patient registries is encouraging, with approximately 25 000 patients with PIDs included in the two registries discussed. Registries such as this are vital for future research, as well as providing an educational resource. PMID:25546748

  14. The 7th International Cryocooler Conference

    NASA Astrophysics Data System (ADS)

    1993-04-01

    The partial contents of this document include the following: SDIO and Air Force Cryocooler Technology Developments at USAF Phillips Laboratory; JPL Cryocooler Development and Test Program Overview; Development and Demonstration of a Diaphragm Stirling 65 K Standard Spacecraft Cryocooler; Stirling Space Cooler; Thermal, Vibration, and Reliability Test Results for a Balanced 80 K Cryocooler; Spacecraft Cooler Characterization; Performance of a Long Life Reverse Brayton Cryocooler; SDI Cryocooler Producibility Program; Miniature Pulse Tube Cooler; Flow Patterns Intrinsic to the Pulse Tube Refrigerator; Experimental Investigation of the Regenerative Magnetic Refrigerator Operating Between 4.2 K and 1.8 K; A 4 K Gifford-McMahon Refrigerator for Radio Astronomy; A Stirling Cycle Cryocooler for 4 K Applications; Regenerator Performance and Refrigeration Mechanism for 4 K GM Refrigerator Using Rare Earth Compound Regenerator Materials; Superfluid Stirling Refrigerator with a Counterflow Regenerator; Graded and Nongraded Regenerator Performance; Evolution of the 10 K Periodic Sorption Refrigerator Concept; Development of a Periodic 10 K Sorption Cryocooler; Assessment of a Hydrogen Joule-Thomson Expander and Vanadium Hydride Sorption Beds for 20 K Cryocoolers; Design of a Metal Hydride Sorption Cryocooler System; Linear Compressor for JT Cryocooler; JT Cryostat with Liquid-Solid Cryogen Reservoir; Design of A Metal Hydride Sorption Cryocooler System; Linear Compressor for JT Cooler; and Phase Equilibria in Cryogenic Mixtures.

  15. 7th International Immunoglobulin Conference: Poster presentations.

    PubMed

    Warnatz, K; Ballow, M; Stangel, M; Bril, V

    2014-12-01

    The pan-European survey provides useful information on the accessibility and trends of intravenous and subcutaneous immunoglobulin (IVIg/SCIg) therapy, which is used to treat primary immunodeficiency disorders (PIDs). Although immunoglobulin (Ig) therapy is the first-line treatment for PIDs, the mechanisms of action of Ig therapy may differ according to the condition it is used to treat. Moreover, intriguing presentations suggest that further investigation is required to understand more clearly both the haematological and immunoregulatory effects of therapeutic immunoglobulin. This can ultimately provide more information on optimizing Ig therapy efficacy, and establish whether individualized dosing regimens for patients will be conducive to better clinical outcomes. In addition to treating autoimmune and inflammatory conditions, there is evidence to suggest that immunoglobulins can potentially play a role in transplantation, which warrants further investigation for future use.

  16. 7th International Immunoglobulin Conference: Immunomodulation

    PubMed Central

    Danieli, M G; Shoenfeld, Y

    2014-01-01

    Rheumatoid arthritis (RA) is a debilitating autoimmune disease that is usually treated aggressively to slow the rate of joint destruction. The therapeutic strategy used at the French centre, described here, is to use the non-biological disease-modifying drug, methotrexate, as first-line therapy and to add biological agents as second-line treatment. The two other autoimmune diseases discussed in this session were immunobullous skin diseases, and secondary recurrent miscarriage (RM). In the former conditions, low levels of pathogenic autoantibodies can be achieved with adjuvant intravenous immunoglobulin (IVIg) therapy, usually in combination with an immunosuppressant. Secondary RM has an autoimmune basis, as shown by high tumour necrosis factor (TNF)-α levels and specific human leucocyte antigen (HLA) polymorphisms. Although the mechanism is not yet known, IVIg may also be an effective treatment, despite the generally low doses used in published studies. PMID:25546788

  17. 7th International Immunoglobulin Conference: Immunomodulation

    PubMed Central

    Danieli, M G; Shoenfeld, Y

    2014-01-01

    Immunomodulation uses synthetic, natural and recombinant preparations to modify the immune response to a desired level, typically to treat specific autoimmune diseases, as will be discussed in this section. Rheumatoid arthritis (RA) is a common systemic autoimmune disease, affecting 1% of the population worldwide. Currently, a first-line disease-modifying therapy for RA is methotrexate; however, more than 40 monoclonal antibodies are in use or under investigation for the treatment of RA. This panoply of biological disease-modifying agents means that clinicians can make use of drugs with different mechanisms of action should one type become ineffective. In autoimmune pemphigus conditions, identification of pathogenic autoantibodies against intercellular cadherin desmoglein 1 and/or 3 antigens is one of the criteria for appropriate diagnosis. In pemphigoid conditions, autoantibodies are directed against bullous pemphigoid antigens BP230 and BP180, and in both types of immunobullous disease intravenous immunoglobulin (IVIg), as adjuvant therapy in combination with a cytotoxic drug, is effective in reducing autoantibody levels, disease severity and background steroid use. Further studies are required to establish the role of monoclonal antibodies in the treatment of autoimmune bullous disease. IVIg may also be effective in another at-risk population with autoimmune disease, namely secondary recurrent miscarriage (RM). However, the mechanism of action of IVIg in secondary RM is largely unknown, although levels of natural killer cell biomarkers, particularly CD56+, have been shown to decline after IVIg treatment [1-6]. Data from meta-analyses of heterogeneous placebo-controlled trials indicate that IVIg may be effective in secondary RM, but most trials to date have used immunomodulatory doses lower than those considered to be efficient in autoimmune disease. The results of a recently completed study may help to address this question. PMID:25546784

  18. The LISA Pathfinder mission

    NASA Astrophysics Data System (ADS)

    Antonucci, F.; Armano, M.; Audley, H.; Auger, G.; Benedetti, M.; Binetruy, P.; Bogenstahl, J.; Bortoluzzi, D.; Bosetti, P.; Brandt, N.; Caleno, M.; Cañizares, P.; Cavalleri, A.; Cesa, M.; Chmeissani, M.; Conchillo, A.; Congedo, G.; Cristofolini, I.; Cruise, M.; Danzmann, K.; De Marchi, F.; Diaz-Aguilo, M.; Diepholz, I.; Dixon, G.; Dolesi, R.; Dunbar, N.; Fauste, J.; Ferraioli, L.; Ferrone, V.; Fichter, W.; Fitzsimons, E.; Freschi, M.; García Marin, A.; García Marirrodriga, C.; Gerndt, R.; Gesa, L.; Gilbert, F.; Giardini, D.; Grimani, C.; Grynagier, A.; Guillaume, B.; Guzmán, F.; Harrison, I.; Heinzel, G.; Hernández, V.; Hewitson, M.; Hollington, D.; Hough, J.; Hoyland, D.; Hueller, M.; Huesler, J.; Jennrich, O.; Jetzer, P.; Johlander, B.; Karnesis, N.; Killow, C.; Llamas, X.; Lloro, I.; Lobo, A.; Maarschalkerweerd, R.; Madden, S.; Mance, D.; Mateos, I.; McNamara, P. W.; Mendes, J.; Mitchell, E.; Monsky, A.; Nicolini, D.; Nicolodi, D.; Nofrarias, M.; Pedersen, F.; Perreur-Lloyd, M.; Plagnol, E.; Prat, P.; Racca, G. D.; Ramos-Castro, J.; Reiche, J.; Romera Perez, J. A.; Robertson, D.; Rozemeijer, H.; Sanjuan, J.; Schleicher, A.; Schulte, M.; Shaul, D.; Stagnaro, L.; Strandmoe, S.; Steier, F.; Sumner, T. J.; Taylor, A.; Texier, D.; Trenkel, C.; Tu, H.-B.; Vitale, S.; Wanner, G.; Ward, H.; Waschke, S.; Wass, P.; Weber, W. J.; Ziegler, T.; Zweifel, P.

    2012-06-01

    In this paper, we describe the current status of the LISA Pathfinder mission, a precursor mission aimed at demonstrating key technologies for future space-based gravitational wave detectors, like LISA. Since much of the flight hardware has already been constructed and tested, we will show that performance measurements and analysis of these flight components lead to an expected performance of the LISA Pathfinder which is a significant improvement over the mission requirements, and which actually reaches the LISA requirements over the entire LISA Pathfinder measurement band.

  19. The LISA Pathfinder Mission

    NASA Astrophysics Data System (ADS)

    McNamara, Paul

    2013-04-01

    LISA Pathfinder, the second of the European Space Agency's Small Missions for Advanced Research in Technology (SMART), is a dedicated technology validation mission for future interferometric spaceborne gravitational wave observatories, for example the proposed eLISA mission. The technologies required for eLISA are many and extremely challenging. This coupled with the fact that some flight hardware cannot be fully tested on ground due to Earth-induced noise, led to the implementation of the LISA Pathfinder mission to test the critical eLISA technologies in a flight environment. LISA Pathfinder essentially mimics one arm of the eLISA constellation by shrinking the 1 million kilometre armlength down to a few tens of centimetres, giving up the sensitivity to gravitational waves, but keeping the measurement technology: the distance between the two test masses is measured using a laser interferometric technique similar to one aspect of the eLISA interferometry system. The scientific objective of the LISA Pathfinder mission consists then of the first in-flight test of low frequency gravitational wave detection metrology. Here I will present an overview of the mission, focusing on scientific and technical goals, followed by the current status of the project.

  20. The LISA Pathfinder Mission

    NASA Astrophysics Data System (ADS)

    Armano, M.; Audley, H.; Auger, G.; Baird, J.; Binetruy, P.; Born, M.; Bortoluzzi, D.; Brandt, N.; Bursi, A.; Caleno, M.; Cavalleri, A.; Cesarini, A.; Cruise, M.; Danzmann, K.; Diepholz, I.; Dolesi, R.; Dunbar, N.; Ferraioli, L.; Ferroni, V.; Fitzsimons, E.; Freschi, M.; Gallegos, J.; García Marirrodriga, C.; Gerndt, R.; Gesa, L. I.; Gibert, F.; Giardini, D.; Giusteri, R.; Grimani, C.; Harrison, I.; Heinzel, G.; Hewitson, M.; Hollington, D.; Hueller, M.; Huesler, J.; Inchauspé, H.; Jennrich, O.; Jetzer, P.; Johlander, B.; Karnesis, N.; Kaune, B.; Korsakova, N.; Killow, C.; Lloro, I.; Maarschalkerweerd, R.; Madden, S.; Mance, D.; Martín, V.; Martin-Porqueras, F.; Mateos, I.; McNamara, P.; Mendes, J.; Mendes, L.; Moroni, A.; Nofrarias, M.; Paczkowski, S.; Perreur-Lloyd, M.; Petiteau, A.; Pivato, P.; Plagnol, E.; Prat, P.; Ragnit, U.; Ramos-Castro, J.; Reiche, J.; Romera Perez, J. A.; Robertson, D.; Rozemeijer, H.; Russano, G.; Sarra, P.; Schleicher, A.; Slutsky, J.; Sopuerta, C. F.; Sumner, T.; Texier, D.; Thorpe, J.; Trenkel, C.; Tu, H. B.; Vetrugno, D.; Vitale, S.; Wanner, G.; Ward, H.; Waschke, S.; Wass, P.; Wealthy, D.; Wen, S.; Weber, W.; Wittchen, A.; Zanoni, C.; Ziegler, T.; Zweifel, P.

    2015-05-01

    LISA Pathfinder (LPF), the second of the European Space Agency's Small Missions for Advanced Research in Technology (SMART), is a dedicated technology validation mission for future spaceborne gravitational wave detectors, such as the proposed eLISA mission. LISA Pathfinder, and its scientific payload - the LISA Technology Package - will test, in flight, the critical technologies required for low frequency gravitational wave detection: it will put two test masses in a near-perfect gravitational free-fall and control and measure their motion with unprecedented accuracy. This is achieved through technology comprising inertial sensors, high precision laser metrology, drag-free control and an ultra-precise micro-Newton propulsion system. LISA Pathfinder is due to be launched in mid-2015, with first results on the performance of the system being available 6 months thereafter. The paper introduces the LISA Pathfinder mission, followed by an explanation of the physical principles of measurement concept and associated hardware. We then provide a detailed discussion of the LISA Technology Package, including both the inertial sensor and interferometric readout. As we approach the launch of the LISA Pathfinder, the focus of the development is shifting towards the science operations and data analysis - this is described in the final section of the paper

  1. The LISA Pathfinder Mission

    NASA Technical Reports Server (NTRS)

    Thorpe, james; McNamara, P. W.

    2011-01-01

    LISA Pathfinder is a dedicated technology demonstration space mission for the Laser Interferometer Space Antenna (LISA), a NASA/ESA collaboration to operate a space-based observatory for gravitational waves in the milli-Hertz band. Although the formal partnership between the agencies was dissolved in the Spring of 2011, both agencies are actively pursuing concepts for LISA-like gravitational wave observatories. These concepts take advantage of the significant technology development efforts that have already been made, especially those of the LISA Pathfinder mission. LISA Pathfinder, which is in the late stages of implementation, will place two test masses in drag-free flight and measure the relative acceleration between them. This measurement will validate a number of technologies that are critical to LISA-like gravitational wave instruments including sensing and control of the test masses, drag-free control laws, microNewton thrusters, and picometer-level laser metrology. We will present the current status of the LISA Pathfinder mission and associated activities.

  2. LISA: Opening New Horizons

    NASA Technical Reports Server (NTRS)

    Centrella, Joan M.

    2011-01-01

    The Laser Interferometer Space Antenna (LISA) is a space-borne observatory that will open the low frequency (approx.0.1-100 mHz) gravitational wave window on the universe. LISA will observe a rich variety of gravitational wave sources, including mergers of massive black holes, captures of stellar black holes by massive black holes in the centers of galaxies, and compact Galactic binaries. These sources are generally long-lived, providing unprecedented opportunities for multi-messenger astronomy in the transient sky. This talk will present an overview of these scientific arenas, highlighting how LISA will enable stunning discoveries in origins, understanding the cosmic order, and the frontiers of knowledge.

  3. EDITORIAL: Proceedings of the 18th International Conference on General Relativity and Gravitation (GRG18) and 7th Edoardo Amaldi Conference on Gravitational Waves (Amaldi7), Sydney, Australia, July 2007

    NASA Astrophysics Data System (ADS)

    Scott, Susan M.; McClelland, David E.

    2008-06-01

    At GRG17 in Dublin in 2004, it was decided to hold GRG18 in Sydney in 2007. Every six years, the GRG conference (held every three years) and Amaldi meeting (held every two years) occur in the same year around July. This was to be the case in 2007. By mutual agreement of the International Society on General Relativity and Gravitation (ISGRG), which oversees the GR conferences and The Gravitational Wave International Committee (GWIC), which oversees the Amaldi meetings, it was decided to hold these two important conferences concurrently, for the first time, at the same venue, namely Sydney. At a time when the gravitational wave community was beginning to explore the possibility of searches to probe various aspects of the theory, the vision was to bring that community together with the community of gravitational theorists in order to better appreciate the work being done by both parties and to explore possibilities for future research using the mutual expertise. The logistics of running two such large meetings concurrently were considerable. The format agreed upon by the ISGRG and GWIC was the following: common plenary sessions in the mornings from Monday to Friday; six parallel GR workshop sessions and an Amaldi session each afternoon from Monday to Friday (except Wednesday); a combined poster session on Wednesday; a full day of Amaldi sessions on the final day (Saturday). The scientific programme for GRG18 was overseen by a Scientific Organising Committee established by the ISGRG and chaired by Professor Sathyaprakash. The scientific programme for Amaldi7 was overseen by GWIC chaired by Professor Cerdonio. One of the highlights of the conferences was the breadth and quality of the plenary programme put together by the scientific committees. Not only did these talks give an excellent snapshot of the entire field at this time, but they also explored the interfaces with other related fields, which proved of special interest to participants. We were given superb

  4. An Overview of the Mock LISA Data Challenges

    NASA Technical Reports Server (NTRS)

    Arnaud, Keith A.; Babak, Stanislav; Baker, John G.; Benacquista, Matthew J.; Cornish, Neil J.; Cutler, Curt; Larson, Shane L.; Sathyaprakash, B. S.; Vallisneri, Michele; Vecchio, Alberto; Vinet, Jean-Yves

    2006-01-01

    The LISA International Science Team Working Group on Data Analysis (LIST-WG1B) is sponsoring several rounds of mock data challenges, with the purpose of fostering the development of LISA data-analysis capabilities, and of demonstrating technical readiness for the maximum science exploitation of the LISA data. The first round of challenge data sets were released at this Symposium. We describe the objectives, structure, and timeline of this program.

  5. Current LISA Spacecraft Design

    NASA Technical Reports Server (NTRS)

    Merkowitz, S. M.; Castellucci, K. E.; Depalo, S. V.; Generie, J. A.; Maghami, P. G.; Peabody, H. L.

    2009-01-01

    The Laser Interferometer Space Antenna (LISA) mission. a space based gravitational wave detector. uses laser metrology to measure distance fluctuations between proof masses aboard three spacecraft. LISA is unique from a mission design perspective in that the three spacecraft and their associated operations form one distributed science instrument. unlike more conventional missions where an instrument is a component of an individual spacecraft. The design of the LISA spacecraft is also tightly coupled to the design and requirements of the scientific payload; for this reason it is often referred to as a "sciencecraft." Here we describe some of the unique features of the LISA spacecraft design that help create the quiet environment necessary for gravitational wave observations.

  6. The LISA Technology Package

    NASA Technical Reports Server (NTRS)

    Livas, Jeff

    2009-01-01

    The LISA Technology Package (LTP) is the payload of the European Space Agency's LISA Pathfinder mission. LISA Pathfinder was instigated to test, in a flight environment, the critical technologies required by LISA; namely, the inertial sensing subsystem and associated control laws and micro-Newton thrusters required to place a macroscopic test mass in pure free-fall. The UP is in the late stages of development -- all subsystems are currently either in the final stages of manufacture or in test. Available flight units are being integrated into the real-time testbeds for system verification tests. This poster will describe the UP and its subsystems, give the current status of the hardware and test campaign, and outline the future milestones leading to the UP delivery.

  7. Testbed for LISA Photodetectors

    NASA Technical Reports Server (NTRS)

    Guzman, Felipe; Livas, Jeffrey; Silverberg, Robert

    2009-01-01

    The Laser Interferometer Space Antenna (LISA) is a gravitational wave observatory consisting of three spacecraft separated by 5 million km in an equilateral triangle whose center follows the Earth in orbit around the Sun but offset in orbital phase by 20 degrees. LISA is designed to observe sources in the frequency range of 0.1 mHz-100 mHz by measuring fluctuations of the inter-spacecraft separation with laser interferometry. Quadrant photodetectors are used to measure both separation and angular orientation. Noise level, phase and amplitude inhomogeneities of the semiconductor response, and channel cross-talk between quadrant cells need to be assessed in order to ensure the 10 pm/Square root(Hz) sensitivity required for the interferometric length measurement in LISA. To this end, we are currently developing a testbed that allows us to evaluate photodetectors to the sensitivity levels required for LISA. A detailed description of the testbed and preliminary results will be presented.

  8. Current LISA Spacecraft Design

    NASA Technical Reports Server (NTRS)

    Merkowitz, Stephen

    2008-01-01

    The Laser Interferometer Space Antenna (LISA) mission, a space based gravitational wave detector, uses laser metrology to measure distance fluctuations between proof masses aboard three spacecraft. LISA is unique from a mission design perspective in that three spacecraft and their associated operations form one distributed science instrument, unlike more conventional missions where an instrument is a component of an individual spacecraft. The design of the LiSA spacecraft is also tightly coupled to the design and requirements of the scientific payload; for this reason it is often referred to as a "sciencecraft." A detailed discussion will be presented that describes the current spacecraft design and mission architecture needed to meet the LISA science requirements.

  9. LISA and its pathfinder

    NASA Astrophysics Data System (ADS)

    The LISA Pathfinder Team

    2015-08-01

    On astronomical scales, gravity is the engine of the Universe. The launch of LISA Pathfinder this year to prepare the technology to detect gravitational waves will help us 'listen' to the whole Universe.

  10. The Mock LISA Data Challenges: History, Status, Prospects

    NASA Technical Reports Server (NTRS)

    Vallisneri, Michele; Babak, Stas; Baker, John; Benacquista, Matt; Cornish, Neil; Crowder, Jeff; Cutler, Curt; Larson, Shane; Littenberg, Tyson; Porter, Edward; Vecchio, Alberto

    2007-01-01

    This slide presentation reviews the importance for the Mock LISA Data Challenges (MLDC). Laser Interferometer Space Antenna (LISA) is a gravitational wave (GW) observatory that will return data such that data analysis is integral to the measurement concept. Further rationale of the MLDC are to kickstart the development of a LISA data-analysis computational infrastructure, and to encourage, track, and compare progress in LISA data-analysis development in the open community. The MLDCs is a coordinated, voluntary effort in GW community, that will periodically issue datasets with synthetic noise and GW signals from sources of undisclosed parameters; increasing difficulty. The challenge participants return parameter estimates and descriptions of search methods. Some of the challenges and the resultant entries are reviewed. The aim is to show that LISA data analysis is possible, and to develop new techniques, using multiple international teams for the development of LISA core analysis tools

  11. Fundamentals of Physics, Extended 7th Edition

    NASA Astrophysics Data System (ADS)

    Halliday, David; Resnick, Robert; Walker, Jearl

    2004-05-01

    No other book on the market today can match the 30-year success of Halliday, Resnick and Walker's Fundamentals of Physics! Fundamentals of Physics, 7th Edition and the Extended Version, 7th Edition offer a solid understanding of fundamental physics concepts, helping readers apply this conceptual understanding to quantitative problem solving, in a breezy, easy-to-understand style. A unique combination of authoritative content and stimulating applications. * Numerous improvements in the text, based on feedback from the many users of the sixth edition (both instructors and students) * Several thousand end-of-chapter problems have been rewritten to streamline both the presentations and answers * 'Chapter Puzzlers' open each chapter with an intriguing application or question that is explained or answered in the chapter * Problem-solving tactics are provided to help beginning Physics students solve problems and avoid common error * The first section in every chapter introduces the subject of the chapter by asking and answering, "What is Physics?" as the question pertains to the chapter * Numerous supplements available to aid teachers and students The extended edition provides coverage of developments in Physics in the last 100 years, including: Einstein and Relativity, Bohr and others and Quantum Theory, and the more recent theoretical developments like String Theory.

  12. The LISA Pathfinder Mission

    NASA Astrophysics Data System (ADS)

    McNamara, Paul W.

    2013-01-01

    Laser Interferometer Space Antenna (LISA) Pathfinder (formerly known as SMART-2) is a European Space Agency mission designed to pave the way for the joint ESA/NASA LISA mission by testing in flight the critical technologies required for space borne gravitational wave detection; it will put two test masses in a near-perfect gravitational free-fall and control and measure their motion with unprecedented accuracy. This is achieved through technology comprising inertial sensors, high precision laser metrology, drag-free control and an ultra precise micro-Newton propulsion system. LISA Pathfinder (LPF) essentially mimics one arm of space-borne gravitational wave detectors by shrinking the million kilometer scale armlengths down to a few tens of centimeters, giving up the sensitivity to gravitational waves, but keeping the measurement technology. The scientific objective of the LPF mission consists then of the first in-flight test of low frequency gravitational wave detection metrology.

  13. A LISA Interferometry Primer

    NASA Technical Reports Server (NTRS)

    Thorpe, James Ira

    2010-01-01

    A key challenge for all gravitational wave detectors in the detection of changes in the fractional difference between pairs of test masses with sufficient precision to measure astrophysical strains with amplitudes on the order of approx.10(exp -21). ln the case of the five million km arms of LISA, this equates to distance measurements on the ten picometer level. LISA interferometry utilizes a decentralized topology, in which each of the sciencecraft houses its own light sources, detectors, and electronics. The measurements made at each of the sciencecraft are then telemetered to ground and combined to extract the strain experienced by the constellation as a whole. I will present an overview of LISA interferometry and highlight some of the key components and technologies that make it possible.

  14. The LISA Pathfinder Mission

    NASA Technical Reports Server (NTRS)

    Stebbins, Robin

    2009-01-01

    LISA Pathfinder (formerly known as SMART-2) is a European Space Agency (ESA) mission designed to pave the way for the joint ESA/NASA Laser Interferometer Space Antenna (LISA) mission by testing in flight the critical technologies required for spaceborne gravitational wave detection: it will put two test masses in a near-perfect gravitational free-fall and control and measure their motion with unprecedented accuracy. LISA Pathfinder is currently in the integration and test phase of the development, and is due to be launched on a dedicated launch vehicle in late 2011, with first results on the performance of the system being available approx 6 months later. This poster will describe the mission in detail, give the current status of the spacecraft development, and highlight the future milestones in the integration and test campaign.

  15. Science requirements for LISA

    NASA Technical Reports Server (NTRS)

    Stebbins, Robin T.

    2008-01-01

    Historically, gravitational wave antennas have been characterized by their detection capability. This is measured in terms of signal-to-noise ratio, and implies a rate of false positives and false negatives. But to do useful astrophysics, one would like to measure - or more properly, estimate - astrophysical parameters of the gravitational wave sources. In the interest of strengthening the connection between science objectives and a specific instrument performance, the LISA community has reformulated the Laser Interferometer Space Antenna (LlSA) science requirements around the anticipated uncertainty in astrophysical parameter estimation. The rationale for this characterization of LlSA and a summary of the astrophysics and fundamental physics that LISA can do will be given. LISA will be able to make precision measurements of sources out to z approximately equal to 10.

  16. The LISA Pathfinder Mission

    NASA Astrophysics Data System (ADS)

    McNamara, Paul

    2015-04-01

    LISA Pathfinder is the second of the European Space Agency's Small Missions for Advanced Research and Technology (SMART). The goal of LISA Pathfinder (LPF) is to demonstrate the technologies required for future laser interferometric spaceborne gravitational wave detectors. The development of the LPF hardware is now over, and final integration and testing of the spacecraft and payload is underway. The delivery of the opto-mechanical heart of the payload is scheduled for Q2 2015, following which the final system tests will be performed. Launch is scheduled for September 2015. First results will be available approximately 3 months after launch. In this presentation I will describe the LISA Pathfinder mission, and provide the current status of the mission and remaining activities to launch and operations.

  17. The Status of LISA

    NASA Astrophysics Data System (ADS)

    Danzmann, Karsten

    The low-frequency part of the gravitational wave spectrum, from 100 micro-Hertz up to 1 Hz, contains the most spectacular sources of gravitational waves. Really high precision measure-ments are possible here, making this frequency range very interesting for both Astronomy and Fundamental Physics. To open this window for observations, we need an observatory in space! LISA, the Laser Interferometer Space Antenna, will comprise three satellites at the corners of an equilateral triangle with 5 Million km armlength. The constellation is inclined against the ecliptic by 60 degrees, following behind the earth in a distance of 50 Million km. Each satellite contains free-flying test masses on almost perturbation-free geodesic lines. Changes in the distances between the test masses will be measured by heterodyne laser interferometry with picometer resolution to detect the spacetime curvature caused by passing gravitational waves. LISA as a collaborative ESA/NASA mission is the most promising candidate for the L1 slot in the Cosmic Visions program of ESA with a launch in 2020. The Beyond Einstein Program Assessment Committee of NASA has just recently recommended LISA as a flagship mission for NASA. Key technologies for LISA will be demonstrated on the precursor mission LISA Pathfinder, to be launched by ESA in 2012. Among these are, in particular, lasers, interferometry, ion thrusters, and drag-free spacecraft control. Flight hardware manufacture for LISA Pathfinder has begun. These technologies will be useful for a variety of other missions, ranging from Fundamental Physics to Geodesy and even telecommunications.

  18. LISA Optical Bench Testbed

    NASA Astrophysics Data System (ADS)

    Lieser, M.; d'Arcio, L.; Barke, S.; Bogenstahl, J.; Diekmann, C.; Diepholz, I.; Fitzsimons, E. D.; Gerberding, O.; Henning, J.-S.; Hewitson, M.; Hey, F. G.; Hogenhuis, H.; Killow, C. J.; Lucarelli, S.; Nikolov, S.; Perreur-Lloyd, M.; Pijnenburg, J.; Robertson, D. I.; Sohmer, A.; Taylor, A.; Tröbs, M.; Ward, H.; Weise, D.; Heinzel, G.; Danzmann, K.

    2013-01-01

    The optical bench (OB) is a part of the LISA spacecraft, situated between the telescope and the testmass. For measuring the inter-spacecraft distances there are several interferometers on the OB. The elegant breadboard of the OB for LISA is developed for the European Space Agency (ESA) by EADS Astrium, TNO Science & Industry, University of Glasgow and the Albert Einstein Intitute (AEI), the performance tests then will be done at the AEI. Here we present the testbed that will be used for the performance tests with the focus on the thermal environment and the laser infrastructure.

  19. The LISA Pathfinder mission

    NASA Astrophysics Data System (ADS)

    McNamara, Paul

    2012-07-01

    LISA Pathfinder, the second of the European Space Agency's Small Missions for Advanced Research in Technology (SMART), is a dedicated technology demonstrator for future spaceborne gravitational wave observatories, for example the proposed ESA mission, NGO. The technologies required for NGO are many and extremely challenging. This coupled with the fact that some flight hardware cannot be fully tested on ground due to Earth-induced noise, led to the implementation of the LISA Pathfinder mission to test the critical NGO technologies in a flight environment. LISA Pathfinder essentially mimics one arm of the NGO constellation by shrinking the 1 million kilometre armlength down to a few tens of centimetres, giving up the sensitivity to gravitational waves, but keeping the measurement technology: the distance between the two test masses is measured using a laser interferometric technique similar to one aspect of the NGO interferometry system. The scientific objective of the LISA Pathfinder mission consists then of the first in-flight test of low frequency gravitational wave detection metrology. Here I will present an overview of the mission, focusing on scientific and technical goals, followed by the current status of the project.

  20. LISA and the LTP

    NASA Astrophysics Data System (ADS)

    Jennrich, O.

    The primary objective of the LISA (Laser Interferometer Space Antenna mission is the detection and observation of gravitational waves from massive black holes (MBH) and galactic binaries in the frequency range 10 -4 Hz … 10 -1 Hz. This low-frequency range is inaccessible to ground-based interferometers due to the background of local gravitational noise and because ground-based interferometers are limited in length to a few kilometres. LISA is envisaged as an ESA/NASA collaborative project, selected an ESA cornerstone mission and included in NASA's strategic plan and with a nominal launch date in 2011. SMART-2 is primarily intended to demonstrate the key technologies for the ESA/NASA collaborative LISA cornerstone mission. The synergy with the technology being used for Darwin motivates the utilization of SMART-2 for both missions. To this end, SMART-2 will accommodate a LISA technology package (LTP), provided by European institutes and industry and possibly also a Disturbance Reduction System (DRS) that is very similar to the LTP and has the same goals but is provided by US institutes and industry.

  1. The LISA Pathfinder Mission

    NASA Astrophysics Data System (ADS)

    McNamara, P.; Antonucci, F.; Armano, M.; Audley, H.; Auger, G.; Benedetti, M.; Binetruy, P.; Bogenstahl, J.; Bortoluzzi, D.; Brandt, N.; Caleno, M.; Cavalleri, A.; Congedo, G.; Cruise, M.; Danzmann, K.; De Marchi, F.; Diaz-Aguilo, M.; Diepholz, I.; Dixton, G.; Dolesi, R.; Dumbar, N.; Fauste, J.; Ferraioli, L.; Ferroni, V.; Fichter, W.; Fitzsimons, E.; Freschi, M.; García Marirrodriga, C.; Gerndt, R.; Gesa, L.; Gibert, F.; Giardini, D.; Grimani, C.; Grynagier, A.; Guzmán, F.; Harrison, I.; Heinzel, G.; Hewitson, M.; Hollington, D.; Hoyland, D.; Hueller, M.; Huesler, J.; Jennrich, O.; Jetzer, P.; Johlander, B.; Karnesis, N.; Korsakova, N.; Killow, C.; Llamas, X.; Lloro, I.; Lobo, A.; Maarschalkerweerd, R.; Madden, S.; Mance, D.; Martin, V.; Mateos, I.; Mendes, J.; Mitchell, E.; Nicolodi, D.; Nofrarias, M.; Perreur-Lloyd, M.; Plagnol, E.; Prat, P.; Ramos-Castro, J.; Reiche, J.; Romera Perez, J. A.; Robertson, D.; Rozemeijer, H.; Russano, G.; Schleicher, A.; Shaul, D.; Sopuerta, C. F.; Sumner, T. J.; Taylor, A.; Texier, D.; Trenkel, C.; Tu, H. B.; Vitale, S.; Wanner, G.; Ward, H.; Waschke, S.; Wass, P.; Wealthy, D.; Wen, S.; Weber, W.; Ziegler, T.; Zweifel, P.

    2013-01-01

    LISA Pathfinder (formerly known as SMART-2) is an European Space Agency mission designed to pave the way for the joint ESA/NASA Laser Interferometer Space Antenna (LISA) mission by testing in flight the critical technologies required for space-borne gravitational wave detection; it will put two test masses in a near-perfect gravitational free-fall and control and measure their motion with unprecedented accuracy. This is achieved through technology comprising inertial sensors, high precision laser metrology, drag-free control, and an ultra precise micro-Newton propulsion system. LISA Pathfinder (LPF) essentially mimics one arm of spaceborne gravitational wave detectors by shrinking the million kilometre scale armlengths down to a few tens of centimetres, giving up the sensitivity to gravitational waves, but keeping the measurement technology. The scientific objective of the LISA Pathfinder mission consists then of the first in-flight test of low frequency gravitational wave detection metrology. In this paper I will give a brief overview of the mission, focusing on scientific and technical goals.

  2. LISA Pathfinder ground testing

    NASA Astrophysics Data System (ADS)

    Guzman, Felipe; LISA Pathfinder Team

    2010-01-01

    The space-based gravitational wave observatory LISA is a joint NASA-ESA mission that requires challenging technology to ensure pure geodetic trajectories of test masses and the interferometric measurement of distance variations between them. The LISA Pathfinder mission is an ESA-launched technology demonstrator of key LISA subsystems such as spacecraft control with micronewton thrusters, test mass drag-free control, and precision laser interferometry between free-flying test masses. Ground testing of pre-flight hardware of the Gravitational Reference Sensor and Optical Metrology subsystems is currently ongoing. Studies have been carried out on very sensitive torsion pendulums that effectively reproduce a free-fall condition for the test mass within a horizontal plane in the lab, down to frequencies < 0.1 mHz. Thermal gradient induced effects, impact of gas molecules, noisy charging, surface charge patches, and other effects have been investigated and their physical models consolidated. A final upper limit on non-modeled disturbances has also been obtained within one order of magnitude of LISA requirements at 1 mHz. The interferometry system has also been extensively studied to identify noise sources and develop approaches to mitigate them. Engineering models of the optical bench, laser head and laser modulators have been interconnected and tested for functionality and noise level in closed-loop operation, demonstrating the required optical metrology sensitivity to test mass displacement. This poster presents the current status in the development and implementation of LISA Pathfinder pre-flight systems and latest results of the ongoing ground testing efforts.

  3. LISA Pathfinder: mission and status

    NASA Astrophysics Data System (ADS)

    Antonucci, F.; Armano, M.; Audley, H.; Auger, G.; Benedetti, M.; Binetruy, P.; Boatella, C.; Bogenstahl, J.; Bortoluzzi, D.; Bosetti, P.; Caleno, M.; Cavalleri, A.; Cesa, M.; Chmeissani, M.; Ciani, G.; Conchillo, A.; Congedo, G.; Cristofolini, I.; Cruise, M.; Danzmann, K.; De Marchi, F.; Diaz-Aguilo, M.; Diepholz, I.; Dixon, G.; Dolesi, R.; Dunbar, N.; Fauste, J.; Ferraioli, L.; Fertin, D.; Fichter, W.; Fitzsimons, E.; Freschi, M.; García Marin, A.; García Marirrodriga, C.; Gerndt, R.; Gesa, L.; Gilbert, F.; Giardini, D.; Grimani, C.; Grynagier, A.; Guillaume, B.; Guzmán, F.; Harrison, I.; Heinzel, G.; Hewitson, M.; Hollington, D.; Hough, J.; Hoyland, D.; Hueller, M.; Huesler, J.; Jeannin, O.; Jennrich, O.; Jetzer, P.; Johlander, B.; Killow, C.; Llamas, X.; Lloro, I.; Lobo, A.; Maarschalkerweerd, R.; Madden, S.; Mance, D.; Mateos, I.; McNamara, P. W.; Mendes, J.; Mitchell, E.; Monsky, A.; Nicolini, D.; Nicolodi, D.; Nofrarias, M.; Pedersen, F.; Perreur-Lloyd, M.; Perreca, A.; Plagnol, E.; Prat, P.; Racca, G. D.; Rais, B.; Ramos-Castro, J.; Reiche, J.; Romera Perez, J. A.; Robertson, D.; Rozemeijer, H.; Sanjuan, J.; Schleicher, A.; Schulte, M.; Shaul, D.; Stagnaro, L.; Strandmoe, S.; Steier, F.; Sumner, T. J.; Taylor, A.; Texier, D.; Trenkel, C.; Tombolato, D.; Vitale, S.; Wanner, G.; Ward, H.; Waschke, S.; Wass, P.; Weber, W. J.; Zweifel, P.

    2011-05-01

    LISA Pathfinder, the second of the European Space Agency's Small Missions for Advanced Research in Technology (SMART), is a dedicated technology demonstrator for the joint ESA/NASA Laser Interferometer Space Antenna (LISA) mission. The technologies required for LISA are many and extremely challenging. This coupled with the fact that some flight hardware cannot be fully tested on ground due to Earth-induced noise led to the implementation of the LISA Pathfinder mission to test the critical LISA technologies in a flight environment. LISA Pathfinder essentially mimics one arm of the LISA constellation by shrinking the 5 million kilometre armlength down to a few tens of centimetres, giving up the sensitivity to gravitational waves, but keeping the measurement technology: the distance between the two test masses is measured using a laser interferometric technique similar to one aspect of the LISA interferometry system. The scientific objective of the LISA Pathfinder mission consists then of the first in-flight test of low frequency gravitational wave detection metrology. LISA Pathfinder is due to be launched in 2013 on-board a dedicated small launch vehicle (VEGA). After a series of apogee raising manoeuvres using an expendable propulsion module, LISA Pathfinder will enter a transfer orbit towards the first Sun-Earth Lagrange point (L1). After separation from the propulsion module, the LPF spacecraft will be stabilized using the micro-Newton thrusters, entering a 500 000 km by 800 000 km Lissajous orbit around L1. Science results will be available approximately 2 months after launch.

  4. LISA Pathfinder data analysis

    NASA Astrophysics Data System (ADS)

    Antonucci, F.; Armano, M.; Audley, H.; Auger, G.; Benedetti, M.; Binetruy, P.; Boatella, C.; Bogenstahl, J.; Bortoluzzi, D.; Bosetti, P.; Caleno, M.; Cavalleri, A.; Cesa, M.; Chmeissani, M.; Ciani, G.; Conchillo, A.; Congedo, G.; Cristofolini, I.; Cruise, M.; Danzmann, K.; De Marchi, F.; Diaz-Aguilo, M.; Diepholz, I.; Dixon, G.; Dolesi, R.; Fauste, J.; Ferraioli, L.; Fertin, D.; Fichter, W.; Fitzsimons, E.; Freschi, M.; García Marin, A.; García Marirrodriga, C.; Gesa, L.; Giardini, D.; Grimani, C.; Grynagier, A.; Guillaume, B.; Guzmán, F.; Harrison, I.; Heinzel, G.; Hewitson, M.; Hollington, D.; Hough, J.; Hoyland, D.; Hueller, M.; Huesler, J.; Jeannin, O.; Jennrich, O.; Jetzer, P.; Johlander, B.; Killow, C.; Llamas, X.; Lloro, I.; Lobo, A.; Maarschalkerweerd, R.; Madden, S.; Mance, D.; Mateos, I.; McNamara, P. W.; Mendes, J.; Mitchell, E.; Monsky, A.; Nicolini, D.; Nicolodi, D.; Nofrarias, M.; Pedersen, F.; Perreur-Lloyd, M.; Perreca, A.; Plagnol, E.; Prat, P.; Racca, G. D.; Rais, B.; Ramos-Castro, J.; Reiche, J.; Romera Perez, J. A.; Robertson, D.; Rozemeijer, H.; Sanjuan, J.; Schulte, M.; Shaul, D.; Stagnaro, L.; Strandmoe, S.; Steier, F.; Sumner, T. J.; Taylor, A.; Texier, D.; Trenkel, C.; Tombolato, D.; Vitale, S.; Wanner, G.; Ward, H.; Waschke, S.; Wass, P.; Weber, W. J.; Zweifel, P.

    2011-05-01

    As the launch of LISA Pathfinder (LPF) draws near, more and more effort is being put in to the preparation of the data analysis activities that will be carried out during the mission operations. The operations phase of the mission will be composed of a series of experiments that will be carried out on the satellite. These experiments will be directed and analysed by the data analysis team, which is part of the operations team. The operations phase will last about 90 days, during which time the data analysis team aims to fully characterize the LPF, and in particular, its core instrument the LISA Technology Package. By analysing the various couplings present in the system, the different noise sources that will disturb the system, and through the identification of the key physical parameters of the system, a detailed noise budget of the instrument will be constructed that will allow the performance of the different subsystems to be assessed and projected towards LISA. This paper describes the various aspects of the full data analysis chain that are needed to successfully characterize the LPF and build up the noise budget during mission operations.

  5. Laser Communication for LISA

    NASA Astrophysics Data System (ADS)

    Ackley, Kendall; Sweeney, Dylan; Mueller, Guido

    2010-10-01

    The Laser Interferometer Space Antenna (LISA) is a joint mission between NASA and ESA to detect gravitational wave radiation between 0.1 and 1 Hz by measuring phase fluctuations of laser heterodyne signals. The phase of the signals must be measured to microradian accuracy. For LISA to be successful the distance between the spacecraft (SC) must be measured to meter precision and the clock signals on each SC must be recorded. These functions will be accomplished using the laser links between the SC. Pseudo random noise (PRN) codes will be modulated onto the light and used to measure the light travel delay between the SC. The clock signals on each SC will be frequency up-converted to GHz frequencies, modulated onto the laser links, and sent to the other SC where it will be recorded and used in post-processing to cancel the clock noise. We have tested components of these systems such as frequency up-converters, electro-optic modulators, and photodetectors, as well as the systems themselves to see if they are capable of meeting their performance requirements for LISA. We will discuss the work being completed at UF. This work is supported by NASA Grant NNX09AF99G.

  6. Proceedings of the Annual Meeting of the North American Chapter of the International Group for the Psychology of Mathematics Education (7th, Columbus, Ohio, October 2-5, 1985).

    ERIC Educational Resources Information Center

    Damarin, Suzanne K., Ed.; Shelton, Marilyn, Ed.

    This proceedings from the annual conference of the North American Chapter of the International Group for the Psychology of Mathematics Education includes the following topics and authors: area measurement (C. B. Beattys, C. A. Maher); error patterns (H. C. Bebout); formative evaluation (J. C. Bergeron, N. Herscovics, N. Nantais); interactive…

  7. Expanding Reading Interest, Response, Achievement; Proceedings of the Annual Conference of the North Carolina Council of the International Reading Association (7th, Greensboro, North Carolina, March 13-14, 1975).

    ERIC Educational Resources Information Center

    Culyer, Richard C., III, Ed.

    This volume presents papers given at the Seventh Annual Conference on Reading of the North Carolina Council of the International Reading Association. General-session addresses include "Reading: The Fassport to the 80s" by Lewis C. Dowdy, "Developing the Habit of Reading Success" by William K. Durr, "Neither Simple-Minded nor Muddle-Headed Be" by…

  8. From laboratory experiments to LISA Pathfinder: achieving LISA geodesic motion

    NASA Astrophysics Data System (ADS)

    Antonucci, F.; Armano, M.; Audley, H.; Auger, G.; Benedetti, M.; Binetruy, P.; Boatella, C.; Bogenstahl, J.; Bortoluzzi, D.; Bosetti, P.; Brandt, N.; Caleno, M.; Cavalleri, A.; Cesa, M.; Chmeissani, M.; Ciani, G.; Conchillo, A.; Congedo, G.; Cristofolini, I.; Cruise, M.; Danzmann, K.; De Marchi, F.; Diaz-Aguilo, M.; Diepholz, I.; Dixon, G.; Dolesi, R.; Dunbar, N.; Fauste, J.; Ferraioli, L.; Fertin, D.; Fichter, W.; Fitzsimons, E.; Freschi, M.; García Marin, A.; García Marirrodriga, C.; Gerndt, R.; Gesa, L.; Giardini, D.; Gibert, F.; Grimani, C.; Grynagier, A.; Guillaume, B.; Guzmán, F.; Harrison, I.; Heinzel, G.; Hewitson, M.; Hollington, D.; Hough, J.; Hoyland, D.; Hueller, M.; Huesler, J.; Jeannin, O.; Jennrich, O.; Jetzer, P.; Johlander, B.; Killow, C.; Llamas, X.; Lloro, I.; Lobo, A.; Maarschalkerweerd, R.; Madden, S.; Mance, D.; Mateos, I.; McNamara, P. W.; Mendes, J.; Mitchell, E.; Monsky, A.; Nicolini, D.; Nicolodi, D.; Nofrarias, M.; Pedersen, F.; Perreur-Lloyd, M.; Perreca, A.; Plagnol, E.; Prat, P.; Racca, G. D.; Rais, B.; Ramos-Castro, J.; Reiche, J.; Romera Perez, J. A.; Robertson, D.; Rozemeijer, H.; Sanjuan, J.; Schleicher, A.; Schulte, M.; Shaul, D.; Stagnaro, L.; Strandmoe, S.; Steier, F.; Sumner, T. J.; Taylor, A.; Texier, D.; Trenkel, C.; Tombolato, D.; Vitale, S.; Wanner, G.; Ward, H.; Waschke, S.; Wass, P.; Weber, W. J.; Zweifel, P.

    2011-05-01

    This paper presents a quantitative assessment of the performance of the upcoming LISA Pathfinder geodesic explorer mission. The findings are based on the results of extensive ground testing and simulation campaigns using flight hardware, flight control and operations algorithms. The results show that, for the central experiment of measuring the stray differential acceleration between the LISA test masses, LISA Pathfinder will be able to verify the overall acceleration noise to within a factor 2 of the LISA requirement at 1 mHz and within a factor 6 at 0.1 mHz. We also discuss the key elements of the physical model of disturbances, coming from LISA Pathfinder and ground measurement that will guarantee the LISA performance.

  9. Recommendations from the Workshop: Environment, Ecology and Sustainable Development ICAE 7th World Assembly

    ERIC Educational Resources Information Center

    Viezzer, Moema L.

    2006-01-01

    One of the workshops presented at the 7th International Council for Adult Education (ICAE) Assembly was focused on environment, ecology, and sustainable development. The workshop had participants from Asia, Africa, Europe, South America, North America and the South Pacific. This article presents a list of recommendations from the workshop.

  10. The LISA accelerometer

    NASA Astrophysics Data System (ADS)

    Rodrigues, M.; Touboul, P.

    2003-10-01

    In the frame of investigating the fundamental nature of gravity, the Laser Interferometer Space Antenna (LISA) mission could open the way to a new kind of observations unreachable from ground. The experiment, based on a V-formation of six drag-free spacecraft, uses the cubic proof masses of inertial sensors to reflect the laser light, acting as reference mirrors of a 5 × 10 9 m arm length interferometer. The proof masses are also used as inertial references for the drag-free control of the spacecraft which constitute in return a shield against external forces. Derived from space electrostatic accelerometers developed at ONERA, such as GRADIO for the ESA ARISTOTELES and now GOCE mission (Bernard and Touboul, 1991), the proposed LISA sensor should shield its proof mass from any accelerometric disturbance at a level of 10 -15ms-2Hz- 1/2. The accurate capacitive sensing of the mass provides its position relative to the satellite with a resolution better than 10 -9m Hz- 1/2 in order to control the satellite orbit and to minimise the disturbances induced by the satellite self gravity or by the proof mass charge. The sensor configuration and accomodation has to be specifically optimised for the mission requirements. Fortunately, the sensor will benefit from the thermal stability of the LISA optical bench environment, i.e. 10 -6K Hz- 1/2, and of the selected materials that exhibit a very low coefficient of thermal expansion (CTE), ensuring a high geometrical stability. Apart from the modeling and the evaluation of the flight characteristics, the necessary indirect ground demonstration of the performance and the interfaces with the drag-free control will have to be considered in detail in the future.

  11. Science with LISA Pathfinder

    NASA Astrophysics Data System (ADS)

    Sumner, T. J.

    2013-01-01

    LISA Pathfinder will offer a unique opportunity to use an extremely sensitive calibrated pair of accelerometers on a drag-free spacecraft platform to perform weak force experiments in an environment not available on Earth. The Science Team has identified a number of interesting tests which could be done after the main technology demonstration mission is completed. Potential tests include a measurement of G in space to a comparable accuracy to existing ground-based measurements, a long-range 1/r2 test and a Sun-Earth saddle point crossing to search for signatures of modified Newtonian dynamics.

  12. LISA Optical Bench Testing

    NASA Astrophysics Data System (ADS)

    Tröbs, M.; d'Arcio, L.; Barke, S.; Bogenstahl, J.; Diekmann, C.; Fitzsimons, E. D.; Gerberding, O.; Hennig, J.; Hey, F. G.; Hogenhuis, H.; Killow, C. J.; Lieser, M.; Lucarelli, S.; Nikolov, S.; Perreur-Lloyd, M.; Pijnenburg, J.; Robertson, D. I.; Sohmer, A.; Taylor, A.; Ward, H.; Weise, D.; Heinzel, G.; Danzmann, K.

    2013-01-01

    Each LISA satellite carries optical benches, one for each test mass, that measure the distance to the local test mass and to the remote optical bench on the distant satellite. Currently, an elegant bread board of the optical bench is developed for the European Space Agency (ESA) by EADS Astrium, TNO Science and Technology, University of Glasgow and the Albert Einstein Institute. To test the optical bench the two interferometers mentioned above must be completed by an external simulator, the test mass and telescope simulator. We give an overview of the simulator layout and performance predictions.

  13. LISA Instrument Performance

    NASA Technical Reports Server (NTRS)

    Livas, Jeffrey C.; Thorpe, James Ira

    2008-01-01

    Laser Interferometer Space Antenna (LISA) is designed to observe gravitational waves in the frequency band from 10(exp -1) to 10(exp -4) Hz where a rich spectrum of sources is expected. The measurements must be made from space to avoid the large motions of the earth that prevent the current generations (eg. LIGO) from operating at these freq8uencies. The technology and expected performance behind this measurement capability will be reviewed with an emphasis on the interferometric measurement system., including recent laboratory results showing a novel tunable frequency stabilized laser.

  14. Assessment of canyon wall failure process from multibeam bathymetry and Remotely Operated Vehicle (ROV) observations, U.S. Atlantic continental margin: Chapter 10 in Submarine mass movements and their consequences: 7th international symposium part II

    USGS Publications Warehouse

    Chaytor, Jason D.; Demopoulos, Amanda W. J.; Ten Brink, Uri; Baxter, Christopher D. P.; Quattrini, Andrea M.; Brothers, Daniel S.; Lamarche, Geoffroy; Mountjoy, Joshu; Bull, Suzanne; Hubble, Tom; Krastel, Sebastian; Lane, Emily; Micallef, Aaron; Moscardelli, Lorena; Mueller, Christof; Pecher, Ingo; Woelz, Susanne

    2016-01-01

    Over the last few years, canyons along the northern U.S. Atlantic continental margin have been the focus of intensive research examining canyon evolution, submarine geohazards, benthic ecology and deep-sea coral habitat. New high-resolution multibeam bathymetry and Remotely Operated Vehicle (ROV) dives in the major shelf-breaching and minor slope canyons, provided the opportunity to investigate the size of, and processes responsible for, canyon wall failures. The canyons cut through thick Late Cretaceous to Recent mixed siliciclastic and carbonate-rich lithologies which impart a primary control on the style of failures observed. Broad-scale canyon morphology across much of the margin can be correlated to the exposed lithology. Near vertical walls, sedimented benches, talus slopes, and canyon floor debris aprons were present in most canyons. The extent of these features depends on canyon wall cohesion and level of internal fracturing, and resistance to biological and chemical erosion. Evidence of brittle failure over different spatial and temporal scales, physical abrasion by downslope moving flows, and bioerosion, in the form of burrows and surficial scrape marks provide insight into the modification processes active in these canyons. The presence of sessile fauna, including long-lived, slow growing corals and sponges, on canyon walls, especially those affected by failure provide a critical, but as yet, poorly understood chronological record of geologic processes within these systems.

  15. LISA Long-Arm Interferometry

    NASA Technical Reports Server (NTRS)

    Thorpe, James I.

    2009-01-01

    An overview of LISA Long-Arm Interferometry is presented. The contents include: 1) LISA Interferometry; 2) Constellation Design; 3) Telescope Design; 4) Constellation Acquisition; 5) Mechanisms; 6) Optical Bench Design; 7) Phase Measurement Subsystem; 8) Phasemeter Demonstration; 9) Time Delay Interferometry; 10) TDI Limitations; 11) Active Frequency Stabilization; 12) Spacecraft Level Stabilization; 13) Arm-Locking; and 14) Embarassment of Riches.

  16. LISA and LISA Pathfinder: Gravitational Wave Observation in Space

    NASA Technical Reports Server (NTRS)

    Guzman, Felipe

    2010-01-01

    The Laser Interferometer Space Antenna (LISA) is a planned NASA-ESA gravitational wave observatory in the frequency range of 0.1 mHz--100 mHz. This observation band is inaccessible to ground-based detectors due to fluctuations in the Earth gravitational field. Gravitational wave sources for LISA include galactic binaries, mergers of supermassive black-hole binaries, extreme-mass-ratio inspirals, and cosmology backgrounds and bursts. LISA is a constellation of three spacecraft separated by 5 million km in an equilateral triangle, whose center follows the Earth in a heliocentric orbit with an orbital phase offset of 20 degrees. Challenging technology is required to ensure pure geodetic trajectories of the six onboard test masses, whose distance fluctuations will be measured by interspacecraft laser interferometers with picometer accuracy. LISA Pathfinder is an ESA-launched technology demonstration mission of key LISA subsystems such as spacecraft control with micronewton thrusters, test mass drag-free control, and precision laser interferometry between free-flying test masses. Ground testing of hardware of the Gravitational Reference Sensor and Optical Metrology subsystems of LISA Pathfinder is currently ongoing. A detailed description of the two missions and an overview of current investigations conducted by the community will be discussed. The current status in development and implementation of LISA Pathfinder pre-flight systems and latest results of the ongoing ground testing efforts will also be presented.

  17. NRP 7th Edition: Are You Prepared?

    PubMed

    Zaichkin, Jeanette; Mccarney, Linda; Weiner, Gary

    2016-01-01

    The seventh edition of the American Academy of Pediatrics/American Heart Association Neonatal Resuscitation Program (NRP) materials must be in use by January 1, 2017. As in previous editions, changes in resuscitation science are based on an international review and consensus of current resuscitation science. The seventh edition NRP materials also include enhancements to training materials aimed at improving the quality of NRP instruction and providing the opportunity for ongoing education. A standardized approach to instructor training, an online Instructor Toolkit, eSim cases, and a new learning management system are among the new resources.

  18. Atomic cluster collisions: ISACC-2015 (7th International Symposium)*

    NASA Astrophysics Data System (ADS)

    Prosmiti, Rita; Villarreal, Pablo; Delgado-Barrio, Gerardo; Solov'yov, Andey V.

    2017-02-01

    The ISACC 2015 brought together nearly a hundred scientists in the field of atomic and molecular cluster physics from around the world. We deliver the Editorial of a topical issue compiling/presenting original research results from some of the participants on both experimental and theoretical studies involving research areas from small clusters to extended molecular systems in the field.

  19. 7th international conference on acid rock drainage

    SciTech Connect

    Barnhisel, R.I.

    2006-07-01

    This meeting also serves as the 23rd annual meeting of the American Society of Mining and Reclamation. The papers discussed various aspects of acid mine drainage including its impact, sustainability issues, case studies, lessons learned, characterization, closure/land use issues, emerging technologies, forestry/ecology, abandoned mine lands, modelling, pit lakes/backfill, soils and overburden, and treatment.

  20. 7th International Immunoglobulin Conference: Immunoglobulin in clinical practice.

    PubMed

    Shapiro, R S; Borte, M

    2014-12-01

    Intravenous and subcutaneous immunoglobulins (IVIg and SCIg, respectively) are increasingly used in clinical practice, not only as replacement therapy but also for immunomodulation. Physicians have learned that primary immunodeficiency (PID) patients are susceptible to recurrent respiratory tract infections even when appropriately treated with immunoglobulin (Ig) therapy. Further investigation will establish whether a combined therapeutic approach including Ig dose optimization will prevent progressive lung disease in PID. The wear-off effects observed with IVIg can be minimized by adjusting the dosing regimen. It is also possible to avoid the cyclic wear-off following transition to SCIg administration. Consideration of benefit versus risk with Ig therapy includes evaluating the potential occurrence of thromboembolic and haemolytic events, which may be more frequent when Ig is administered in high doses and in the presence of pre-existing risk factors. The ability to select an administration method from IVIg, SCIg or hyaluronidase-facilitated SCIg infusions provides patient choice and alternatives if one or other administration route is not suitable for a patient. The evolution in indications, applications, and understanding of Ig therapy described here has reinforced the need for robust methods to prioritize Ig use.

  1. 7th International Immunoglobulin Conference: Mechanisms of action.

    PubMed

    Basta, M; Branch, D R

    2014-12-01

    Although intravenous immunoglobulin (IVIg) is widely used for replacement therapy in immunodeficiencies and to treat autoimmune and inflammatory diseases, its mechanisms of action are not fully understood. Examination of immunoglobulin (Ig) receptors, including the Fc-gamma receptors (FCγRs) and the neonatal Fc receptor, have revealed genetic variations that are linked to autoimmune diseases and to the efficacy of IVIg treatment. However, the beneficial effect of IVIg encompasses multiple mechanisms of action. One of these is scavenging of activated complement fragments, such as C3a, C5a, C3b and C4b, by infused Ig molecules. This interaction prevents binding of complement fragments to their receptors on target cells, thus attenuating the immune damage. Additionally, anti-inflammatory effects may be facilitated by IgA via specific receptors and/or complement scavenging. Glycosylation of both the Fc- and Fab-fragments has also been implicated in the anti-inflammatory action of IVIg. Although there is evidence to support a role for sialylated IgG glycovariants in mediating the effect of IVIg, evidence from animal models of inflammatory disease suggest that sialylation may not be a critical factor. However, an increase in IgG glycosylation has been observed following IVIg treatment in Guillain-Barré syndrome patients, and this has been associated with improved clinical outcomes.

  2. Proceedings of the 7th International Cryocooler Conference, part 3

    NASA Astrophysics Data System (ADS)

    1993-04-01

    Partial contents include: SDIO and Air Force Cryocooler Technology Developments at USAF Phillips Laboratory; JPL Cryocooler Development and Test Program Overview; Development and Demonstration of a Diaphragm Stirling 65 K Standard Spacecraft Cryocooler; Stirling Space Cooler; Thermal, Vibration, and Reliability Test Results for a Balanced 80 K Cryocooler; Spacecraft Cooler Characterization; Performance of a Long Life Reverse Brayton Cryocooler; SDI Cryocooler Producibility Program; Miniature Pulse Tube Cooler; Flow Patterns Intrinsic to the Pulse Tube Refrigerator; Experimental Investigation of the Regenerative Magnetic Refrigerator Operating Between 4.2 K and 1.8 K; A 4 K Gifford-McMahon Refrigerator for Radio Astronomy; A Stirling Cycle Cryocooler for 4 K Applications; Regenerator Performance and Refrigeration Mechanism for 4 K GM Refrigerator Using Rare Earth Compound Regenerator Materials; Superfluid Stirling Refrigerator with a Counterflow Regenerator; Graded and Nongraded Regenerator Performance; Evolution of the 10 K Periodic Sorption Refrigerator Concept; Development of a Periodic 10 K Sorption Cryocooler; Assessment of a Hydrogen Joule-Thomson Expander and Vanadium Hydride Sorption Beds for 20 K Cryocoolers; Design of a Metal Hydride Sorption Cryocooler System; Linear Compressor for JT Cryocooler; JT Cryostat with Liquid-Solid Cryogen Reservoir; Design of A Metal Hydride Sorption Cryocooler System; Linear Compressor for JT Cooler; Phase Equilibria in Cryogenic Mixtures.

  3. Proceedings of the 7th International Cryocooler Conference, part 2

    NASA Astrophysics Data System (ADS)

    1993-04-01

    Partial contents include: SDIO and Air Force Cryocooler Technology Developments at USAF Phillips Laboratory; JPL Cryocooler Development and Test Program Overview; Development and Demonstration of a Diaphragm Stirling 65 K Standard Spacecraft Cryocooler; Stirling Space Cooler; Thermal, Vibration, and Reliability Test Results for a Balanced 80 K Cryocooler; Spacecraft Cooler Characterization; Performance of a Long Life Reverse Brayton Cryocooler; SDI Cryocooler Producibility Program; Miniature Pulse Tube Cooler; Flow Patterns Intrinsic to the Pulse Tube Refrigerator; Experimental Investigation of the Regenerative Magnetic Refrigerator Operating Between 4.2 K and 1.8 K; A 4 K Gifford-McMahon Refrigerator for Radio Astronomy; A Stirling Cycle Cryocooler for 4 K Applications; Regenerator Performance and Refrigeration Mechanism for 4 K GM Refrigerator Using Rare Earth Compound Regenerator Materials; Superfluid Stirling Refrigerator with a Counterflow Regenerator; Graded and Nongraded Regenerator Performance; Evolution of the 10 K Periodic Sorption Refrigerator Concept; Development of a Periodic 10 K Sorption Cryocooler; Assessment of a Hydrogen Joule-Thomson Expander and Vanadium Hydride Sorption Beds for 20 K Cryocoolers; Design of a Metal Hydride Sorption Cryocooler System; Linear Compressor for JT Cryocooler; JT Cryostat with Liquid-Solid Cryogen Reservoir; Design of A Metal Hydride Sorption Cryocooler System; Linear Compressor for JT Cooler; Phase Equilibria in Cryogenic Mixtures.

  4. Proceedings of the 7th International Cryocooler Conference, part 1

    NASA Astrophysics Data System (ADS)

    1993-04-01

    Partial contents include: SDIO and Air Force Cryocooler Technology Developments at USAF Phillips Laboratory; JPL Cryocooler Development and Test Program Overview; Development and Demonstration of a Diaphragm Stirling 65 K Standard Spacecraft Cryocooler; Stirling Space Cooler; Thermal, Vibration, and Reliability Test Results for a Balanced 80 K Cryocooler; Spacecraft Cooler Characterization; Performance of a Long Life Reverse Brayton Cryocooler; SDI Cryocooler Producibility Program; Miniature Pulse Tube Cooler; Flow Patterns Intrinsic to the Pulse Tube Refrigerator; Experimental Investigation of the Regenerative Magnetic Refrigerator Operating Between 4.2 K and 1.8 K; A 4 K Gifford-McMahon Refrigerator for Radio Astronomy; A Stirling Cycle Cryocooler for 4 K Applications; Regenerator Performance and Refrigeration Mechanism for 4 K GM Refrigerator Using Rare Earth Compound Regenerator Materials; Superfluid Stirling Refrigerator with a Counterflow Regenerator; Graded and Nongraded Regenerator Performance; Evolution of the 10 K Periodic Sorption Refrigerator Concept; Development of a Periodic 10 K Sorption Cryocooler; Assessment of a Hydrogen Joule-Thomson Expander and Vanadium Hydride Sorption Beds for 20 K Cryocoolers; Design of a Metal Hydride Sorption Cryocooler System; Linear Compressor for JT Cryocooler; JT Cryostat with Liquid-Solid Cryogen Reservoir; Design of A Metal Hydride Sorption Cryocooler System; Linear Compressor for JT Cooler; Phase Equilibria in Cryogenic Mixtures.

  5. 7TH International Symposium: Nanostructure: Physics and Technology

    DTIC Science & Technology

    1999-01-01

    sample structure were described in [4]. NEA state was achieved by activation of atomically clean surfaces with cesium and oxygen. The quantum yield at the...activation layer degradation due to the cesium - oxygen disbalance. In our case the degradation was accompanied by a considerable shift of the EDC low-energy...is about nh - 3 x 1010 cm- 2. Photoluminescence (PL), reflectivity and spin-flip Raman scattering ( SFRS ) spectra were measured at 1.6 K and in

  6. PREFACE: 7th International Conference on Applied Electrostatics (ICAES-2012)

    NASA Astrophysics Data System (ADS)

    Li, Jie

    2013-03-01

    ICAES is an important conference organized every four years by the Committee on Electrostatics of the Chinese Physical Society, which serves as a forum for scientists, educators and engineers interested in the fundamentals, applications, disasters and safety of electrostatics, etc. In recent years, new techniques, applications and fundamental theories on electrostatics have developed considerably. ICAES-7, held in Dalian, China, from 17-19 September 2012, aimed to provide a forum for all scholars to report the newest developments in electrostatics, to probe the questions that scholars faced and to discuss fresh ideas related to electrostatics. ICAES-7 was co-organized and hosted by Dalian University of Technology, and was sponsored by the Ministry of Education of China, the National Natural Science Foundation of China, Dalian University of Technology, Nanjing Suman Electronics Co. Ltd (Suman, China), Shekonic (Yangzhou Shuanghong, China) Electric/Mechanical Co. Ltd, and Suzhou TA&A Ultra Clean Technology Co. Ltd. (China). On behalf of the organizing committee of ICAES-7, I express my great appreciation for their support of the conference. Over 160 scholars and engineers from many countries including Croatia, The Czech Republic, D.P.R. Korea, Germany, Japan, Malaysia, Poland, Russia, the United States of America, China attended ICAES-7, and the conference collected and selected 149 papers for publication. The subjects of those papers cover the fundamentals of electrostatics, electrostatic disaster and safety, and electrostatic application (e.g. precipitation, pollutant control, biological treatment, mixture separation and food processing, etc). I cordially thank all authors and attendees for their support, and my appreciation is also given to the conference honorary chair, the organizing committee and advisory committee, and the conference secretaries for their hard work. ICAES-7 is dedicated to the memory of Professor Jen-Shih Chang (professor emeritus in the Faculty of Engineering, McMaster University, Canada), Haitian Scholar of Dalian University of Technology (China), who passed away on 27 February 2011. Professor Chang was active in research fields including the applications of electrostatics, electromagnetic hydrodynamics, plasma environmental pollution control technologies, etc and he contributed much to the development of these fields. Professor Chang was the visiting professor at some Key Universities in China and was the friend of Chinese scholars engaged in electrostatics. Professor Chang was also active in joining and supporting the previous ICAES. We will cherish the memory of Professor Jen-Shih Chang forever. Professor Jie Li Proceedings Editor Dalian, September 2012 Conference photograph

  7. Spacetime Metrology with LISA Pathfinder

    NASA Astrophysics Data System (ADS)

    Congedo, Giuseppe

    2012-04-01

    LISA is the proposed ESA-NASA gravitational wave detector in the 0.1 mHz - 0.1 Hz band. LISA Pathfinder is the down-scaled version of a single LISA arm. The arm - named Doppler link - can be treated as a differential accelerometer, measuring the relative acceleration between test masses. LISA Pathfinder - the in-flight test of the LISA instrumentation - is currently in the final implementation and planned to be launched in 2014. It will set stringent constraints on the ability to put test masses in geodesic motion to within the required differential acceleration of 3times10^{-14} m s^{-2} Hz^{-1/2} and track their relative motion to within the required differential displacement measurement noise of 9times10^{-12} m Hz^{-1/2}, around 1 mHz. Given the scientific objectives, it will carry out - for the first time with such high accuracy required for gravitational wave detection - the science of spacetime metrology, in which the Doppler link between two free-falling test masses measures the curvature. This thesis contains a novel approach to the calculation of the Doppler response to gravitational waves. It shows that the parallel transport of 4-vectors records the history of gravitational wave signals. In practice, the Doppler link is implemented with 4 bodies in LISA and 3 bodies in LISA Pathfinder. To compensate for noise sources a control logic is implemented during the measurement. The closed-loop dynamics of LISA Pathfinder can be condensed into operators acting on the motion coordinates, handling the couplings, as well as the cross-talks. The scope of system identification is the optimal calibration of the instrument. This thesis describes some data analysis procedures applied to synthetic experiments and shows the relevance of system identification for the success of LISA Pathfinder in demonstrating the principles of spacetime metrology for all future space-based missions.

  8. Laser Interferometry for Gravitational Wave Observation: LISA and LISA Pathfinder

    NASA Technical Reports Server (NTRS)

    Guzman, Felipe

    2010-01-01

    The Laser Interferometer Space Antenna (LISA) is a planned NASA-ESA gravitational wave observatory in the frequency range of 0.1mHz-100mHz. This observation band is inaccessible to ground-based detectors due to the large ground motions of the Earth. Gravitational wave sources for LISA include galactic binaries, mergers of supermasive black-hole binaries, extreme-mass-ratio inspirals, and possibly from as yet unimagined sources. LISA is a constellation of three spacecraft separated by 5 million km in an equilateral triangle, whose center follows the Earth in a heliocentric orbit with an orbital phase offset oF 20 degrees. Challenging technology is required to ensure pure geodetic trajectories of the six onboard test masses, whose distance fluctuations will be measured by interspacecraft laser interferometers with picometer accuracy. LISA Pathfinder is an ESA-launched technology demonstration mission of key LISA subsystems such us spacecraft control with micro-newton thrusters, test mass drag-free control, and precision laser interferometry between free-flying test masses. Ground testing of flight hardware of the Gravitational Reference Sensor and Optical Metrology subsystems of LISA Pathfinder is currently ongoing. An introduction to laser interferometric gravitational wave detection, ground-based observatories, and a detailed description of the two missions together with an overview of current investigations conducted by the community will bc discussed. The current status in development and implementation of LISA Pathfinder pre-flight systems and latest results of the ongoing ground testing efforts will also be presented

  9. PREFACE: 7th European Conference on Applied Superconductivity (EUCAS '05)

    NASA Astrophysics Data System (ADS)

    Weber, Harald W.; Sauerzopf, Franz M.

    2006-07-01

    This issue of Journal of Physics: Conference Series contains those contributed papers that were submitted to the Conference Proceedings of the 7th European Conference on Applied Superconductivity (EUCAS '05) on 11 - 15 September 2005. The plenary and invited papers were published in the journal Superconductor Science and Technology 19 2006 (March issue). The scientific aims of EUCAS '05 followed the tradition established at the preceding conferences in Göttingen, Edinburgh, Eindhoven, Sitges (Barcelona), Lyngby (Copenhagen) and finally Sorrento (Napoli). The focus was placed on the interplay between the most recent developments in superconductor research and the positioning of applications of superconductivity in the marketplace. Although initially founded as an exchange forum mainly for European scientists, it has gradually developed into a truly international meeting with significant attendance from the Far East and the United States. The Vienna conference attracted 813 participants in the scientific programme and 90 guests: of the particpants 59% were from Europe, 31% from the Far East, 6% from the United States and Canada and 4% from other nations worldwide. There were 32 plenary and invited lectures highlighting the state-of-the-art in the areas of materials, large-scale and small-scale applications, and 625 papers were contributed (556 of these were posters) demonstrating the broad range of exciting activities in all research areas of our field. A total of 27 companies presented their most recent developments in the field. This volume contains 349 papers, among them 173 on materials (49.6%), 90 on large scale applications (25.8%) and 86 on small scale applications (24.6%). EUCAS '05 generated a feeling of optimism and enthusiasm for this fascinating field of research and for its well established technological potential, especially among the numerous young researchers attending this Conference. We are grateful to all those who participated in the meeting and

  10. Concept Mapping Improves Metacomprehension Accuracy among 7th Graders

    ERIC Educational Resources Information Center

    Redford, Joshua S.; Thiede, Keith W.; Wiley, Jennifer; Griffin, Thomas D.

    2012-01-01

    Two experiments explored concept map construction as a useful intervention to improve metacomprehension accuracy among 7th grade students. In the first experiment, metacomprehension was marginally better for a concept mapping group than for a rereading group. In the second experiment, metacomprehension accuracy was significantly greater for a…

  11. 7th meeting of the global arthritis research network

    PubMed Central

    2011-01-01

    Last October, the 7th meeting of the Global Arthritis Research Network was held in Zurich, Switzerland. European and American experts who have made major recent contributions to molecular biology got together to provide insights into novel technologies and approaches useful for biomedical research, especially for research on arthritis and related conditions. PMID:21892971

  12. The LISA Pathfinder Radiation Monitor

    NASA Astrophysics Data System (ADS)

    Wass, P. J.; Araújo, H.; Boatella, C.; Chmeissani, M.; Hajdas, W.; Lobo, A.; Puigdengoles, C.; Sumner, T.

    2006-11-01

    We present the concept, design and testing of the radiation monitor for LISA Pathfinder. Galactic cosmic rays (GCRs) and solar energetic particles (SEPs) will cause charging of the LISA Pathfinder test masses producing unwanted disturbances which could be significant during a large solar eruption. A radiation monitor on board LISA Pathfinder, using silicon PIN diodes as particle detectors, will measure the particle flux responsible for charging. It will also be able to record spectral information to identify solar energetic particle events. The design of the monitor was supported by Monte Carlo simulations which allow detailed predictions of the radiation monitor performance. We present these predictions as well as the results of high-energy proton tests carried out at the Paul Scherrer Institute, Switzerland. The tests show good agreement with our simulations and confirm the capability of the radiation monitor to perform well in the space environment, meeting all science requirements.

  13. LISA Pathfinder: A Mission Status

    NASA Astrophysics Data System (ADS)

    Hewitson, Martin; LISA Pathfinder Team Team

    2016-03-01

    On December 3rd at 04:04 UTC, The European Space Agency launched the LISA Pathfinder satellite on board a VEGA rocket from Kourou in French Guiana. After a series of orbit raising manoeuvres and a 2 month long transfer orbit, LISA Pathfinder arrived at L1. Following a period of commissioning, the science operations commenced at the start of March, beginning the demonstration of technologies and methodologies which pave the way for a future large-scale gravitational wave observatory in space. This talk will present the scientific goals of the mission, discuss the technologies being tested, elucidate the link to a future space-based observatory, such as LISA, and present preliminary results from the in-orbit operations and experiments.

  14. LISA Technology Development at GSFC

    NASA Technical Reports Server (NTRS)

    Thorpe, James Ira; McWilliams, S.; Baker, J.

    2008-01-01

    The prime focus of LISA technology development efforts at NASA/GSFC has been in LISA interferometry, specifically in the area of laser frequency noise mitigation. Laser frequency noise is addressed through a combination of stabilization and common-mode rejection. Current plans call for two stages of stabilization, pre-stabilization to a local frequency reference and further stabilization using the constellation as a frequency reference. In order for these techniques to be used simultaneously, the pre-stabilization step must provide an adjustable frequency offset. Here, we report on a modification to the standard modulation/demodulation techniques used to stabilize to optical cavities that generates a frequency-tunable reference from a fixed-length cavity. This technique requires no modifications to the cavity itself and only minor modifications to the components. The measured noise performance and dynamic range of the laboratory prototype meets the LISA requirements.

  15. Trends in Science and Technology Education: Reviews and Keynotes of the 7th IOSTE Symposium. (7th, De Koningshof Veldhoven, The Netherlands, August 23-31, 1994). Part 4.

    ERIC Educational Resources Information Center

    van Trommel, Jacques, Ed.

    The overall theme of the 7th International Organization for Science and Technology Education (IOSTE) symposium was "science and technology education in a demanding society". The aim of the symposium was to examine the state of science and technology education in the context of the main theme and to reflect on desirable and feasible educational…

  16. LISA: Detecting Gravitational Waves from Space

    NASA Technical Reports Server (NTRS)

    Livas, Jeff

    2009-01-01

    The laser interferometer space antenna (LISA), a joint NASA/ESA mission, will be the first dedicated gravitational wave detector in space. This presentation will provide a tutorial of the LISA measurement concept.

  17. The science behind the 7th edition Tumour, Node, Metastasis staging system for lung cancer.

    PubMed

    Marshall, Henry M; Leong, Steven C; Bowman, Rayleen V; Yang, Ian A; Fong, Kwun M

    2012-02-01

    The Tumour, Node, Metastasis (TNM) system for classifying lung cancer is the cornerstone of modern lung cancer treatment and underpins comparative research; yet is continuously evolving through updated revisions. The recently published Union for International Cancer Control 7th Edition TNM Classification for lung cancer addresses many of its predecessor's shortcomings and has been subject to rigorous evidence-based methodology. It is based on a retrospective analysis of over 80 000 lung cancer patients treated between 1990 and 2000 carried out by the International Association for the Study of Lung Cancer. The dataset was truly international and included patients treated by all modalities. Extensive internal and external validation of the findings has ensured that the recommendations are robust and generalizable. For the first time, a single classification system has been shown to be applicable not only to non-small cell lung cancer, but also to be of prognostic significance in small cell lung cancer and bronchopulmonary carcinoid tumours. We review the history of the Union for International Cancer Control TNM staging system, the changes in the most recent 7th edition and the strength of the scientific basis motivating these changes. Limitations of the current staging edition are explored, post-publication independent validation studies are reviewed, and the future of TNM staging for lung cancer is discussed.

  18. Communique: Special Issue on the International Scientific Conference and Exhibit and the 7th Session of the International Co-Ordinating Council for MAB (Paris, Sept. 22-Oct. 2, 1981) = Numero special sur la Conference Scientifique Internationale et Exposition et al 7e session du Counseil International de Coordination du MAB (Paris, du 22 Sept. au 2 Oct. 1981).

    ERIC Educational Resources Information Center

    Communique, 1982

    1982-01-01

    Presented are summaries of two separate but closely-related conferences. The International Scientific Conference and Exhibit, organized to mark the 10th anniversary of the Man and the Biosphere Program (MAB), was based on the theme "ecology in practice: establishing a scientific basis for land management." This summary includes: a 10…

  19. Report of the Quadrennial Review of Military Compensation (7th)

    DTIC Science & Technology

    1992-08-21

    the matter is deeper, involv- The 7th QRMC reviewed the literature dealing ing policy choices between providing allowances or with the relationship...Report of the Seventh Quadrennial Review of Military Compensation AUGUST. 21 1992 DTIC gf ELECTE M AY 27 1993 D -1)Ijj~iiI@.1z OF 7T pi oe im i...COVERED 21 AUG 92 Final -- _ _ 4. TITLE AND SUBTITLE 5. FUNDING NUMBERS Report of the Seventh Quadrennial Review of Military Compensation ~ngaae’r

  20. Laser frequency stabilization for LISA

    NASA Technical Reports Server (NTRS)

    Mueller, Guido; McNamara, Paul; Thorpe, Ira; Camp, Jordan

    2005-01-01

    The requirement on laser frequency noise in the Laser Interferometer Space Antenna (LISA) depends on the velocity and our knowledge of the position of each spacecraft of the interferometer. Currently it is assumed that the lasers must have a pre-stabilized frequency stability of 30Hz/square root of Hz over LISA'S most sensitive frequency band (3 mHz - 30 mHz). The intrinsic frequency stability of even the most stable com- mercial lasers is several orders of magnitude above this level. Therefore it is necessary to stabilize the laser frequency to an ultra-stable frequency reference which meets the LISA requirements. The baseline frequency reference for the LISA lasers are high finesse optical cavities based on ULE spacers. We measured the stability of two ULE spacer cavities with respect to each other. Our current best results show a noise floor at, or below, 30 Hz/square root of Hz above 3 mHz. In this report we describe the experimental layout of the entire experiment and discuss the limiting noise sources.

  1. The LISA Project at NASA

    NASA Technical Reports Server (NTRS)

    Stebbins, Robin T.

    2008-01-01

    Although officially in early Phase A, LISA is currently classified as "under-study" at NASA. It has a very high recommendation from the 2000 decadal survey. and has received strong endorsements at all reviews. Mission formulation and technology development continue at modest levels. The Project is starting preparations for the next decadal survey, expected to commence in 2009.

  2. Interview with Lisa Shipley. Interviewed by Lisa Parks.

    PubMed

    Shipley, Lisa

    2013-08-01

    Lisa Shipley is Vice President of Pharmacokinetics, Pharmacodynamics and Drug Metabolism at Merck Research Laboratories. She is responsible for preclinical and clinical ADME activities and molecular biomarker assay development activities at all Merck research sites and support of all programs from discovery through to post-product launch. Prior to joining Merck in 2008, Shipley spent over 20 years at Eli Lilly and Company in roles of increasing responsibility, including the positions of executive director at Lean Six Sigma and vice president of Drug Disposition, PK/PD and Trial Simulations. Shipley obtained her undergraduate degree from McDaniel College and her doctoral degree in Pharmacology and Toxicology from the University of Maryland at Baltimore. This interview was conducted by Lisa Parks, Assistant Commissioning Editor of Bioanalysis.

  3. Alzheimer's disease: a report from the 7th Kuopio Alzheimer symposium.

    PubMed

    Haapasalo, Annakaisa; Pikkarainen, Maria; Soininen, Hilkka

    2015-10-01

    The 7th Kuopio Alzheimer symposium was held on 11-13 June, 2015, in Kuopio, Finland and attracted ~250 attendees from 14 different countries around the world. The theme for the symposium in its seventh year was 'From mechanisms to prevention and intervention of Alzheimer's disease'. The 3-day international scientific symposium composed of seven oral sessions and a poster session. The program, spanning from molecular mechanisms to prevention, prediction, diagnosis and treatment of Alzheimer's disease, provided a forum for the attendees to share their research, network and to obtain a comprehensive overview of the current status and future directions of research into Alzheimer's disease.

  4. LISA technology department at JPL

    NASA Technical Reports Server (NTRS)

    Harb, Charles C.; Chiao, Meng P.; Gromov, Konstantin

    2003-01-01

    The Laser Interferometer Space Antenna (LISA) project requires technology developments on many fronts. A physical understanding of the LISA subsystems is a precursor to tacjling the requirements needed to ensure a successful mission. This can only be achieved by developing the concepts in the lab prior to developing the payload. This poster presents updates on laboratory activities intended to prove the feasibility of measuring proof mass back reaction forces of less than 3fN/(square root)Hz at 1 mHz; the sensing of the proof mass position with in 2 nm/(square root)above the 3 mHz; and the resolution and accuracy of the phase-meter to better than 10 pm/(square root)Hz above the 3 mHz.

  5. Overview of the LISA Phasemeter

    NASA Technical Reports Server (NTRS)

    Shaddock, Daniel A.; Ware, B.; Halverson, P.; Spero, R. E.; Klipstein, B.

    2006-01-01

    The LISA phasemeter is required to measure the phase of an electrical signal with an error less than 3 (micro)cycles/pHz over times scales from 1 to 1000 seconds. This phase sensitivity must be achieved in the presence of laser phase fluctuations 108 times larger than the target sensitivity. Other challenging aspects of the measurement are that the heterodyne frequency varies from 2 to 20 MHz and the signal contains multiple frequency tones that must be measured. The phasemeter architecture uses high-speed analog to digital conversion followed by a digital phase locked loop. An overview of the phasemeter architecture is presented along with results for the breadboard LISA Phasemeter demonstrating that critical requirements are met.

  6. Highlights from the 7th European meeting on molecular diagnostics.

    PubMed

    Loonen, Anne Jm; Schuurman, Rob; van den Brule, Adriaan Jc

    2012-01-01

    This report presents the highlights of the 7th European Meeting on Molecular Diagnostics held in Scheveningen, The Hague, The Netherlands, 12-14 October 2011. The areas covered included molecular diagnostics applications in medical microbiology, virology, pathology, hemato-oncology, clinical genetics and forensics. Novel real-time amplification approaches, novel diagnostic applications and new technologies, such as next-generation sequencing, PCR electrospray-ionization TOF mass spectrometry and techniques based on the detection of proteins or other molecules, were discussed. Furthermore, diagnostic companies presented their future visions for molecular diagnostics in human healthcare.

  7. Ligand Identification Scoring Algorithm (LISA)

    PubMed Central

    Zheng, Zheng; Merz, Kenneth M.

    2011-01-01

    A central problem in de novo drug design is determining the binding affinity of a ligand with a receptor. A new scoring algorithm is presented that estimates the binding affinity of a protein-ligand complex given a three-dimensional structure. The method, LISA (Ligand Identification Scoring Algorithm), uses an empirical scoring function to describe the binding free energy. Interaction terms have been designed to account for van der Waals (VDW) contacts, hydrogen bonding, desolvation effects and metal chelation to model the dissociation equilibrium constants using a linear model. Atom types have been introduced to differentiate the parameters for VDW, H-bonding interactions and metal chelation between different atom pairs. A training set of 492 protein-ligand complexes was selected for the fitting process. Different test sets have been examined to evaluate its ability to predict experimentally measured binding affinities. By comparing with other well known scoring functions, the results show that LISA has advantages over many existing scoring functions in simulating protein-ligand binding affinity, especially metalloprotein-ligand binding affinity. Artificial Neural Network (ANN) was also used in order to demonstrate that the energy terms in LISA are well designed and do not require extra cross terms. PMID:21561101

  8. LISA Propulsion Module Separation Study

    NASA Technical Reports Server (NTRS)

    Merkowitz, Stephen

    2004-01-01

    The Laser Interferometer Space Antenna (LISA) mission is a space-borne gravitational wave detector consisting of three spacecraft in heliocentric orbit. Each spacecraft is delivered to it operational orbit by a propulsion module. Because of the strict thermal and mass balancing requirements of LISA, the baseline mission concept requires that the propulsion module separate from the sciencecraft after delivery. The only propulsion system currently baselined for the sciencecraft are micronewton level thrusters, such as FEEP or colloid thrusters, that are used to balance the 30-40 microN of solar radiation pressure and provide the drag-free and attitude control of the spacecraft. Due to these thrusters limited authority, the separation of the propulsion module from the sciencecraft must be well controlled to not induce a large tip-off rotation of the sciencecraft. We present here the results of a design study of the propulsion module separation system that is shown to safely deliver the LISA sciencecraft to its final operational orbit.

  9. Ligand Identification Scoring Algorithm (LISA).

    PubMed

    Zheng, Zheng; Merz, Kenneth M

    2011-06-27

    A central problem in de novo drug design is determining the binding affinity of a ligand with a receptor. A new scoring algorithm is presented that estimates the binding affinity of a protein-ligand complex given a three-dimensional structure. The method, LISA (Ligand Identification Scoring Algorithm), uses an empirical scoring function to describe the binding free energy. Interaction terms have been designed to account for van der Waals (VDW) contacts, hydrogen bonding, desolvation effects, and metal chelation to model the dissociation equilibrium constants using a linear model. Atom types have been introduced to differentiate the parameters for VDW, H-bonding interactions, and metal chelation between different atom pairs. A training set of 492 protein-ligand complexes was selected for the fitting process. Different test sets have been examined to evaluate its ability to predict experimentally measured binding affinities. By comparing with other well-known scoring functions, the results show that LISA has advantages over many existing scoring functions in simulating protein-ligand binding affinity, especially metalloprotein-ligand binding affinity. Artificial Neural Network (ANN) was also used in order to demonstrate that the energy terms in LISA are well designed and do not require extra cross terms.

  10. LISA telescope spacer design investigations

    NASA Astrophysics Data System (ADS)

    Sanjuan, Josep; Mueller, Guido; Livas, Jeffrey; Preston, Alix; Arsenovic, Petar; Castellucci, Kevin; Generie, Joseph; Howard, Joseph; Stebbins, Robin

    The Laser Interferometer Space Antenna (LISA) is a space-based gravitational wave observa-tory with the goal of observing Gravitational Waves (GWs) from astronomical sources in a frequency range from 30 µHz to 0.1 Hz. The detection of GWs at such low frequency requires measurements of distances at the pico-meter level between bodies separated by 5 million kilo-meters. The LISA mission consists of three identical spacecraft (SC) separated by 5 × 106 km forming an equilateral triangle. Each SC contains two optical assemblies and two vacuum en-closures housing one proof mass (PM) in geodesic (free fall) motion each. The two assemblies on one SC are each pointing towards an identical assembly on each of the other two SC to form a non-equal arm interferometer. The measurement of the GW strain is done by measuring the change in the length of the optical path between the PMs of one arm relative to the other arms caused by the pass of a GW. An important element of the Interferometric Measurement System (IMS) is the telescope which, on one hand, gathers the light coming from the far SC (˜100 pW) and, on the other hand, expands and collimates the small outgoing beam ( 1 W) and sends it to the far SC. Due to the very demanding sensitivity requirements care must be taken in the design and validation of the telescope not to degrade the IMS performance. For instance, the diameter of the telescope sets the the shot noise of the IMS and depends critically on the diameter of the primary and the divergence angle of the outgoing beam. As the telescope is rather fast telescope, the divergence angle is a critical function of the overall separation between the primary and secondary. Any long term changes of the distance of more than a a few micro-meter would be detrimental to the LISA mission. Similarly challenging are the requirements on the in-band path-length noise for the telescope which has to be kept below 1 pm Hz-1/2 in the LISA band. Different configurations (on-axis/off axis

  11. Fundamentals of Physics, Student Study Guide, Extended 7th Edition

    NASA Astrophysics Data System (ADS)

    Halliday, David; Resnick, Robert; Walker, Jearl

    2004-06-01

    No other book on the market today can match the 30-year success of Halliday, Resnick and Walker's Fundamentals of Physics! Fundamentals of Physics, 7th Edition and the Extended Version, 7th Edition offer a solid understanding of fundamental physics concepts, helping readers apply this conceptual understanding to quantitative problem solving, in a breezy, easy-to-understand style. A unique combination of authoritative content and stimulating applications. * Numerous improvements in the text, based on feedback from the many users of the sixth edition (both instructors and students) * Several thousand end-of-chapter problems have been rewritten to streamline both the presentations and answers * 'Chapter Puzzlers' open each chapter with an intriguing application or question that is explained or answered in the chapter * Problem-solving tactics are provided to help beginning Physics students solve problems and avoid common error * The first section in every chapter introduces the subject of the chapter by asking and answering, "What is Physics?" as the question pertains to the chapter * Numerous supplements available to aid teachers and students The extended edition provides coverage of developments in Physics in the last 100 years, including: Einstein and Relativity, Bohr and others and Quantum Theory, and the more recent theoretical developments like String Theory.

  12. Multi-Messenger Astronomy: White Dwarf Binaries, LISA and GAIA

    NASA Astrophysics Data System (ADS)

    Bueno, Michael; Breivik, Katelyn; Larson, Shane L.

    2017-01-01

    The discovery of gravitational waves has ushered in a new era in astronomy. The low-frequency band covered by the future LISA detector provides unprecedented opportunities for multi-messenger astronomy. With the Global Astrometric Interferometer for Astrophysics (GAIA) mission, we expect to discover about 1,000 eclipsing binary systems composed of a WD and a main sequence star - a sizeable increase from the approximately 34 currently known binaries of this type. In advance of the first GAIA data release and the launch of LISA within the next decade, we used the Binary Stellar Evolution (BSE) code simulate the evolution of White Dwarf Binaries (WDB) in a fixed galaxy population of about 196,000 sources. Our goal is to assess the detectability of a WDB by LISA and GAIA using the parameters from our population synthesis, we calculate GW strength h, and apparent GAIA magnitude G. We can then use a scale factor to make a prediction of how many multi- messenger sources we expect to be detectable by both LISA and GAIA in a galaxy the size of the Milky Way. We create binaries 10 times to ensure randomness in distance assignment and average our results. We then determined whether or not astronomical chirp is the difference between the total chirp and the GW chirp. With Astronomical chirp and simulations of mass transfer and tides, we can gather more information about the internal astrophysics of stars in ultra-compact binary systems.

  13. LISA Telescope Spacer Design Issues

    NASA Technical Reports Server (NTRS)

    Livas, Jeff; Arsenovic, P.; Catelluci, K.; Generie, J.; Howard, J.; Stebbins, Howard R.; Preston, A.; Sanjuan, J.; Williams, L.; Mueller, G.

    2010-01-01

    The LISA mission observes gravitational waves by measuring the separations between freely floating proof masses located 5 million kilometers apart with an accuracy of - 10 picometers. The separations are measured interferometrically. The telescope is an afocal Cassegrain style design with a magnification of 80x. The entrance pupil has a 40 cm diameter and will either be centered on-axis or de-centered off-axis to avoid obscurations. Its two main purposes are to transform the small diameter beam used on the optical bench to a diffraction limited collimated beam to efficiently transfer the metrology laser between spacecraft, and to receive the incoming light from the far spacecraft. It transmits and receives simultaneously. The basic optical design and requirements are well understood for a conventional telescope design for imaging applications, but the LISA design is complicated by the additional requirement that the total optical path through the telescope must remain stable at the picometer level over the measurement band during the mission to meet the measurement accuracy. We describe the mechanical requirements for the telescope and the preliminary work that has been done to understand the materials and mechanical issues associated with the design of a passive metering structure to support the telescope and to maintain the spacing between the primary and secondary mirrors in the LISA on-orbit environment. This includes the requirements flowdown from the science goals, thermal modeling of the spacecraft and telescope to determine the expected temperature distribution, layout options for the telescope including an on- and off-axis design. Plans for fabrication and testing will be outlined.

  14. Preliminary LISA Telescope Spacer Design

    NASA Technical Reports Server (NTRS)

    Livas, J.; Arsenovic, P.; Catellucci, K.; Generie, J.; Howard, J.; Stebbins, R. T.

    2010-01-01

    The Laser Interferometric Space Antenna (LISA) mission observes gravitational waves by measuring the separations between freely floating proof masses located 5 million kilometers apart with an accuracy of approximately 10 picometers. The separations are measured interferometrically. The telescope is an afocal Cassegrain style design with a magnification of 80x. The entrance pupil has a 40 cm diameter and will either be centered on-axis or de-centered off-axis to avoid obscurations. Its two main purposes are to transform the small diameter beam used on the optical bench to a diffraction limited collimated beam to efficiently transfer the metrology laser between spacecraft, and to receive the incoming light from the far spacecraft. It transmits and receives simultaneously. The basic optical design and requirements are well understood for a conventional telescope design for imaging applications, but the LISA design is complicated by the additional requirement that the total optical path through the telescope must remain stable at the picometer level over the measurement band during the mission to meet the measurement accuracy. This poster describes the requirements for the telescope and the preliminary work that has been done to understand the materials and mechanical issues associated with the design of a passive metering structure to support the telescope and to maintain the spacing between the primary and secondary mirrors in the LISA on-orbit environment. This includes the requirements flowdown from the science goals, thermal modeling of the spacecraft and telescope to determine the expected temperature distribution,layout options for the telescope including an on- and off-axis design, and plans for fabrication and testing.

  15. Characterization of Photoreceivers for LISA

    NASA Technical Reports Server (NTRS)

    Cervantes, F. Guzman; Livas, J.; Silverberg, R.; Buchanan, E.; Stebbins, R.

    2010-01-01

    LISA will use quadrant photo receivers as front-end devices for the phase meter measuring the motion of drag-free test masses in both angular orientation and separation. We have set up a laboratory testbed for the characterization of photo receivers. Some of the limiting noise sources have been identified and their contribution has been either measured or determined from the measured data. We have built a photo receiver with a 0.5 mm diameter quadrant photodiode with an equivalent input noise of better than 1.8 pA/(square root of)Hz below 20 MHz and a 3 dB bandwidth of 34 MHz.

  16. Paths to the LISA Laser

    NASA Technical Reports Server (NTRS)

    Camp, Jordan B.

    2010-01-01

    The LISA mission requires a highly stable, low noise laser with 1 W output that will operate for the 5 year mission lifetime. The best way to achieve this is with a master oscillator power amplifier design, which allows the noise and lifetime requirements to be addressed to a large extent independently. We are working with two aerospace contractors who are performing reliability studies on oscillator designs that our laboratory at Goddard is evaluating. I will describe the oscillator designs we are considering and the reliability studies now underway.

  17. LISA Pathfinder instrument data analysis

    NASA Astrophysics Data System (ADS)

    Guzman, Felipe

    LISA Pathfinder (LPF) is an ESA-launched demonstration mission of key technologies required for the joint NASA-ESA gravitational wave observatory in space, LISA. As part of the LPF interferometry investigations, analytic models of noise sources and corresponding noise subtrac-tion techniques have been developed to correct for effects like the coupling of test mass jitter into displacement readout, and fluctuations of the laser frequency or optical pathlength difference. Ground testing of pre-flight hardware of the Optical Metrology Subsystem is currently ongoing at the Albert Einstein Institute Hannover. In collaboration with NASA Goddard Space Flight Center, the LPF mission data analysis tool LTPDA is being used to analyze the data product of these tests. Furthermore, the noise subtraction techniques and in-flight experiment runs for noise characterization are being defined as part of the mission experiment master plan. We will present the data analysis outcome of pre-flight hardware ground tests and possible noise subtraction strategies for in-flight instrument operations.

  18. LISA Pathfinder Instrument Data Analysis

    NASA Technical Reports Server (NTRS)

    Guzman, Felipe

    2010-01-01

    LISA Pathfinder (LPF) is an ESA-launched demonstration mission of key technologies required for the joint NASA-ESA gravitational wave observatory in space, LISA. As part of the LPF interferometry investigations, analytic models of noise sources and corresponding noise subtraction techniques have been developed to correct for effects like the coupling of test mass jitter into displacement readout, and fluctuations of the laser frequency or optical pathlength difference. Ground testing of pre-flight hardware of the Optical Metrology subsystem is currently ongoing at the Albert Einstein Institute Hannover. In collaboration with NASA Goddard Space Flight Center, the LPF mission data analysis tool LTPDA is being used to analyze the data product of these tests. Furthermore, the noise subtraction techniques and in-flight experiment runs for noise characterization are being defined as part of the mission experiment master plan. We will present the data analysis outcome of preflight hardware ground tests and possible noise subtraction strategies for in-flight instrument operations.

  19. 7th Annual Symposium on Self-Monitoring of Blood Glucose (SMBG), May 8–10, 2014, Helsinki, Finland

    PubMed Central

    Mlinac, Anita; Hinzmann, Rolf

    2014-01-01

    Abstract International experts in the fields of diabetes, diabetes technology, endocrinology, mobile health, sport science, and regulatory issues gathered for the 7th Annual Symposium on Self-Monitoring of Blood Glucose (SMBG). The aim of this meeting was to facilitate new collaborations and research projects to improve the lives of people with diabetes. The 2014 meeting comprised a comprehensive scientific program, parallel interactive workshops, and two keynote lectures. PMID:25211215

  20. Black Holes, Gravitational Waves, and LISA

    NASA Technical Reports Server (NTRS)

    Baker, John

    2009-01-01

    Binary black hole mergers are central to many key science objectives of the Laser Interferometer Space Antenna (LISA). For many systems the strongest part of the signal is only understood by numerical simulations. Gravitational wave emissions are understood by simulations of vacuum General Relativity (GR). I discuss numerical simulation results from the perspective of LISA's needs, with indications of work that remains to be done. Some exciting scientific opportunities associated with LISA observations would be greatly enhanced if prompt electromagnetic signature could be associated. I discuss simulations to explore this possibility. Numerical simulations are important now for clarifying LISA's science potential and planning the mission. We also consider how numerical simulations might be applied at the time of LISA's operation.

  1. System modelling for LISA Pathfinder

    NASA Astrophysics Data System (ADS)

    Diaz-Aguiló, Marc; Grynagier, Adrien; Rais, Boutheina

    LISA Pathfinder is the technology demonstrator for LISA, a space-borne gravitational waves observatory. The goal of the mission is to characterise the dynamics of the LISA Technology Package (LTP) to prove that on-board experimental conditions are compatible with the de-tection of gravitational waves. The LTP is a drag-free dynamics experiment which includes a control loop with sensors (interferometric and capacitive), actuators (capacitive actuators and thrusters), controlled disturbances (magnetic coils, heaters) and which is subject to various endogenous or exogenous noise sources such as infrared pressure or solar wind. The LTP experiment features new hardware which was never flown in space. The mission has a tight operation timeline as it is constrained to about 100 days. It is therefore vital to have efficient and precise means of investigation and diagnostics to be used during the on-orbit operations. These will be conducted using the LTP Data Analysis toolbox (LTPDA) which allows for simulation, parameter identification and various analyses (covariance analysis, state estimation) given an experimental model. The LTPDA toolbox therefore contains a series of models which are state-space representations of each component in the LTP. The State-Space Models (SSM) are objects of a state-space class within the LTPDA toolbox especially designed to address all the requirements of this tool. The user has access to a set of linear models which represent every satellite subsystem; the models are available in different forms representing 1D, 2D and 3D systems, each with settable symbolic and numeric parameters. To limit the possible errors, the models can be automatically linked to produce composite systems and closed-loops of the LTP. Finally, for the sake of completeness, accuracy and maintainability of the tool, the models contain all the physical information they mimic (i.e. variable units, description of parameters, description of inputs/outputs, etc). Models

  2. Characterization of photodetectors for LISA

    NASA Astrophysics Data System (ADS)

    Guzman, Felipe; Livas, Jeffrey; Silverberg, Robert

    The Laser Interferometer Space Antenna (LISA) is a gravitational wave observatory in the frequency range of 0.1 mHz -100 mHz consisting of three spacecraft separated by 5 million km in an equilateral triangle whose center follows the Earth in a heliocentric orbit with an orbital phase offset of 20 degrees. Gravitational waves will be measured as distance fluctuations be-tween test masses moving along geodetic trajectories that are located in different spacecraft. Quadrant photodiodes are used as detectors in inter-spacecraft laser interferometers to measure √ both angular orientation and separation with a sensitivity of better than 10 pm/ Hz. A labora-tory testbed for the characterization of photodetectors has been set up to measure noise levels, phase and amplitude spatial inhomogeneities, and cross-talk level between detector quadrants. We will present a detailed description of our test plan and current results of these investigations.

  3. Gravitational science with LISA Pathfinder

    NASA Astrophysics Data System (ADS)

    Trenkel, C.; Kemble, S.

    2009-03-01

    We investigate the potential of conducting interesting gravitational science experiments with LISA Pathfinder, by executing well defined de-orbiting manoeuvres following the nominal mission. Preliminary work suggests that the residual control authority of the micropropulsion system is sufficient to follow trajectories that cross the region surrounding the Sun-Earth saddle point, and also include one or multiple Earth flybys. Crossing the saddle point region may allow tests of Modified Newtonian Dynamics (MOND), while the flybys may potentially shed some light on the so-called flyby anomaly. We present some sample trajectories and discuss the limitations of the current model. Finally, we discuss the work required to take these ideas from the proof of principle presented here, to a concrete proposal for an extended mission.

  4. Fiber Laser Development for LISA

    NASA Technical Reports Server (NTRS)

    Numata, Kenji; Chen, Jeffrey R.

    2009-01-01

    We have developed a linearly-polarized Ytterbium-doped fiber ring laser with single longitudinal-mode output at 1064nm for LISA and other space applications. Single longitudinal-mode selection was achieved by using a fiber Bragg grating (FBG) and a fiber Fabry-Perot (FFP). The FFP also serves as a frequency-reference within our ring laser. Our laser exhibits comparable low frequency and intensity noise to Non-Planar Ring Oscillator (NPRO). By using a fiber-coupled phase modulator as a frequency actuator, the laser frequency can be electro-optically tuned at a rate of 100kHz. It appears that our fiber ring laser is promising for space applications where robustness of fiber optics is desirable.

  5. Characterization of Photodetectors for LISA

    NASA Technical Reports Server (NTRS)

    Guzman, Felipe; Livas, Jeffrey; Silverberg, Robert F.

    2010-01-01

    The Laser Interferometer Space Antenna (LISA) is a gravitational wave observatory in the frequency range of 0.1 mHz - 100 mHz consisting of three spacecraft separated by :5 million km in an equilateral triangle whose center follows the Earth in a heliocentric orbit with an orbital phase offset of 20 degrees. Gravitational waves will be measured as distance fluctuations between test masses moving along geodetic trajectories that are located in different spacecraft. Quadrant photo diodes are used as detectors in inter-spacecraft laser interferometers to measure both angular orientation and separation with a sensitivity of better than 10 pm/(square root of (HZ)). A laboratory testbed for the characterization of photodetectors has been set up to measure noise levels, phase and amplitude spatial inhomogeneities and cross-talk level between detector quadrants We will present a detailed description of our test plan and current results of these investigations.

  6. Report of the 7th African Rotavirus Symposium, Cape Town, South Africa, 8th November 2012.

    PubMed

    Seheri, L M; Mwenda, J M; Page, N

    2014-11-12

    The 7th African Rotavirus Symposium was held in Cape Town, South Africa, on the 8th November 2012 as a Satellite Symposium at the First International African Vaccinology Conference. Over 150 delegates participated in this symposium including scientists, clinicians, health officials, policymakers and vaccine manufacturers from across Africa. Key topics discussed included rotavirus surveillance, rotavirus vaccine introduction, post rotavirus vaccine impact analysis and intussusception data and surveillance in Africa. The symposium provided early rotavirus vaccine adopter countries in Africa (South Africa, Ghana and Botswana) an opportunity to share up-to-date information on vaccine introduction, and allowed colleagues to share experiences in establishing routine rotavirus surveillance (Tanzania, Niger and Rwanda). Overall, the symposium highlighted the high burden of rotavirus in Africa, and the need to continue to strengthen efforts in preventing rotavirus diarrhoea in Africa.

  7. Proceedings of the 7th US/German Workshop on Salt Repository Research, Design, and Operation.

    SciTech Connect

    Hansen, Francis D.; Steininger, Walter; Bollingerfehr, Willhelm

    2017-01-01

    The 7th US/German Workshop on Salt Repository Research, Design, and Operation was held in Washington, DC on September 7-9, 2016. Over fifty participants representing governmental agencies, internationally recognized salt research groups, universities, and private companies helped advance the technical basis for salt disposal of radioactive waste. Representatives from several United States federal agencies were able to attend, including the Department of Energy´s Office of Environmental Management and Office of Nuclear Energy, the Environmental Protection Agency, the Nuclear Regulatory Commission, and the Nuclear Waste Technical Review Board. A similar representation from the German ministries showcased the covenant established in a Memorandum of Understanding executed between the United States and Germany in 2011. The US/German workshops´ results and activities also contribute significantly to the Nuclear Energy Agency Salt Club repository research agenda.

  8. End-to-end simulations for the LISA Technology Package

    NASA Astrophysics Data System (ADS)

    Hannen, V. M.; Smit, M.; Hoyng, P.; Selig, A.; Schleicher, A.

    2003-05-01

    We present an end-to-end simulation facility which has been developed in the framework of the LISA Technology Package (LTP) architect study for SMART-2, the technology demonstration mission that precedes LISA. The simulator evolves positions and orientations of the spacecraft and two test masses contained in the inertial sensors of LTP under the influence of external and internal forces and torques and under the influence of control loops for satellite drag-free control (DFC) and electrostatic test mass suspension. Altogether, a coupled system with 18 degrees of freedom is solved numerically. A series of test runs has been performed to verify the correct functioning of the various models contained in the end-to-end simulator and to provide a preliminary assessment of the performance of DFC algorithms and control laws for test mass suspension, which are currently foreseen for use in the basic operation mode of LTP.

  9. LISACode: A scientific simulator of LISA

    NASA Astrophysics Data System (ADS)

    Petiteau, Antoine

    2011-12-01

    LISACode is a simulator of the LISA mission. Its ambition is to achieve a new degree of sophistication allowing to map, as closely as possible, the impact of the different subsystems on the measurements. Its also a useful tool for generating realistic data including several kind of sources (Massive Black Hole binaries, EMRIs, cosmic string cusp, stochastic background, etc) and for preparing their analysis. It's fully integrated to the Mock LISA Data Challenge. LISACode is not a detailed simulator at the engineering level but rather a tool whose purpose is to bridge the gap between the basic principles of LISA and a future, sophisticated end-to-end simulator.

  10. The University of Florida LISA interferometer simulator

    NASA Astrophysics Data System (ADS)

    Mueller, Guido; Hochman, Steven; Mitryk, Shawn; Sanjuan Munoz, Jose; Preston, Alix; Sweeney, Dylan; Yu, Yinan; Tanner, David B.; Mueller, Guido

    Interferometric gravitational wave detectors such as LISA are built around two major subsys-tems. Gravitational reference sensors (GRS) consist of several freely-falling proof masses which follow variations in space time caused by passing gravitational waves. Spurious accelerations of the proof masses caused by technical or environmental forces have to be below the fN/rtHz level in the frequency band of interest. Interferometer measurement systems (IMS) measure the changes in the distances between the proof masses with sufficient sensitivity. The GRS-system for LISA has been developed over the last ten years and will be tested in a dedicated test mission, the LISA Test Package (LTP), scheduled for launch in 2012. The IMS of LISA is one of the most dynamic and longest interferometers ever envisioned. It consists of many subsystems which depend on the long light-travel times, the changes in the light-travel times and the induced Doppler shifts. The signals of the IMS are beat tones taken between vari-ous lasers at various locations on the three spacecraft. The phase evolution of each signal is measured against on-board clocks, after which linear combinations between appropriately time-shifted signals are formed to cancel about 10 orders of magnitude of laser frequency noise and thereby reach LISA sensitivity. Achieving 10 orders of magnitude of common mode rejection is already a daunting task for a small static interferometer in an optical laboratory. LISA is a very large and highly dynamic interferometer with constantly changing arms which for exam-ple requires to adapt permanently the noise cancelling linear combinations to the current arm lengths and spacecraft velocities while continuously monitoring the relative noise between the three independent on-board clocks. The University of Florida LISA Interferometer Simulator (UFLIS) is a hardware-in-the-loop simulator which includes multiple lasers, LISA-like signal travel-times and LISA-like Doppler shifts. UFLIS

  11. Mitigation of Laser Frequency Noise for LISA

    NASA Technical Reports Server (NTRS)

    Thorpe, Ira J.

    2009-01-01

    The Laser Interferometer Space Antenna (LISA) is a proposed detector of gravitational waves in the 0.1 mHz - 0.1 Hz band. LISA will measure gravitational wave strain at the 10(exp -21) level by monitoring the distance between freely-falling test masses s(exp -11) m. These distance measurements will be made using heterodyne interferometry with multiple light sources on moving platforms with changing baselines, all of which cause frequency noise to couple into the displacement measurement. I will describe how LISA interferometry mitigates the effects of laser frequency noise through active suppression and common mode rejection. Recent laboratory developments will also be discussed.

  12. LISACode: A scientific simulator of LISA

    SciTech Connect

    Petiteau, Antoine; Auger, Gerard; Halloin, Hubert; Jeannin, Olivier; Plagnol, Eric; Pireaux, Sophie; Regimbau, Tania; Vinet, Jean-Yves

    2008-01-15

    A new LISA simulator (LISACode) is presented. Its ambition is to achieve a new degree of sophistication allowing to map, as closely as possible, the impact of the different subsystems on the measurements. LISACode is not a detailed simulator at the engineering level but rather a tool whose purpose is to bridge the gap between the basic principles of LISA and a future, sophisticated end-to-end simulator. This is achieved by introducing, in a realistic manner, most of the ingredients that will influence LISA's sensitivity as well as the application of TDI combinations. Many user-defined parameters allow the code to study different configurations of LISA thus helping to finalize the definition of the detector. Another important use of LISACode is in generating time-series for data analysis developments.

  13. Laser ranging and communications for LISA.

    PubMed

    Sutton, Andrew; McKenzie, Kirk; Ware, Brent; Shaddock, Daniel A

    2010-09-27

    The Laser Interferometer Space Antenna (LISA) will use Time Delay Interferometry (TDI) to suppress the otherwise dominant laser frequency noise. The technique uses sub-sample interpolation of the recorded optical phase measurements to form a family of interferometric combinations immune to frequency noise. This paper reports on the development of a Pseudo-Random Noise laser ranging system used to measure the sub-sample interpolation time shifts required for TDI operation. The system also includes an optical communication capability that meets the 20 kbps LISA requirement. An experimental demonstration of an integrated LISA phase measurement and ranging system achieved a ≈ 0.19 m rms absolute range error with a 0.5Hz signal bandwidth, surpassing the 1 m rms LISA specification. The range measurement is limited by mutual interference between the ranging signals exchanged between spacecraft and the interaction of the ranging code with the phase measurement.

  14. Lisa's Lemonade Stand: Exploring Algebraic Ideas.

    ERIC Educational Resources Information Center

    Billings, Esther M. H.; Lakatos, Tracy

    2003-01-01

    Presents an activity, "Lisa's Lemonade Stand," that actively engages students in algebraic thinking as they analyze change by investigating relationships between variables and gain experience describing and representing these relationships graphically. (YDS)

  15. COMPARATION OF REFRACTIVE RESULTS WITH BIFOCAL IMPLANTS AT LISA 809 AND TRIFOCAL AT LISA TRI839.

    PubMed

    Postolache, Cristian; Postolache, Oana

    2015-01-01

    The purpose of this paper is to make a comparison between the results obtained with AT LISA 809 bifocal IOL and trifocal AT LISA 839. Interest was represented especially by the evaluation of intermediate vision for the 2 implants. 18 patients (36 eyes) operated in Gauss Clinic in 2014 were included in the study: 9 patients (18 eyes) with bifocal implant AT LISA 809 and 9 patients (18 eyes) with bilateral implantation AT LISA 839 trifocal lens. Results showed that implant trifocal provided better visual results for intermediate vision to bifocal implant, as there were not significant differences between the two, in terms of distance vision and near vision.

  16. Space Detection of Gravitational Waves (lisa)

    NASA Astrophysics Data System (ADS)

    de Araujo, J. C. Neves; Buchman, S.; Cavalleri, A.; Danzmann, K.; Doles, R.; Fontana, G.; Hanso, J.; Hueller, M.; Sigurdsso, S.; Turneaure, J.; Ungarell, C.; Vecchi, A.; Vital, S.; Webe, W.

    2002-12-01

    The Laser Interferometer Space Antenna (LISA) mission is designed to observe gravitational waves from galactic and extra-galactic binary systems, including gravitational waves generated in the vicinity of the very massive black holes found in the centers of many galaxies. Acting as a giant Michelson interferometer the three spacecraft flying 5 million km apart will open the era of astronomy in the gravitational spectrum. We give an introduction to the mission and describe the status of selected experimental, theoretical, and planning LISA work, as reported at the Ninth Marcel Grossman Meeting in 2000 in Rome. We discuss the three areas of technology challenges facing the mission inertial sensors, micronewton thrusters, and picometer interferometry. We report on the progress in the development of free falling moving test-masses for LISA and for the related technology demonstration mission. We present simple formulas to evaluate the performance of the device as a function of the various design parameters, and we compare them with preliminary experimental results from a test prototype we are developing. Quantitative agreement is found. The gravitational radiation emitted during the final stages of coalescence of stellar mass compact objects with low massive black holes is a signal detectable by LISA. It will also provide the opportunity of measuring relativistic strong field effects. A brief discussion addresses the detection by LISA of gravitational waves generated by cataclysmic binary variables at frequencies below 1 mHz. Finally the prospects for cosmology work with LISA type antennas are being analyzed.

  17. Self-Gravity Modeling for LISA

    NASA Technical Reports Server (NTRS)

    Merkowitz, Stephen

    2004-01-01

    The Laser Interferometer Space Antenna (LISA) mission, a space based gravitational wave detector, uses laser metrology to measure distance fluctuations between proof masses aboard three spacecraft. The total acceleration disturbance to each proof mass is required to be below 3 x 10(exp 15) m/sq square root of Hz. Self-gravity noise due to spacecraft distortion and spacecraft motion is expected to be a significant contributor to the acceleration noise budget. To minimize these effects, the gravitational field at each proof mass must be kept as small, flat, and constant as possible. It is estimated that the static field must be kept below 5 x 10(exp -10) m/sq s with a gradient below 3 x 10(exp -8)/sq s in order to meet the required noise levels. Most likely it will not be possible to directly verify by measurements that the LISA spacecraft meets these requirements; they must be verified by models. The LISA Integrated Modeling team developed a new self-gravity tool that calculates the gravitational forces and moments on the proof masses to aid in the design and verification of the LISA spacecraft. We present here an overview of&e tool and the latest self-gravity results calculated using the current baseline design of LISA. We also present results of a self-gravity analysis of the ST-7 DRS package that will fly on the LISA Pathfinder mission.

  18. 3. PHOTOGRAPHIC COPY OF MASTER PLAN, DETAIL SITE PLAN, 7TH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. PHOTOGRAPHIC COPY OF MASTER PLAN, DETAIL SITE PLAN, 7TH CAVALRY BUILDINGS, DATED SEPTEMBER 10, 1951, SEE ARROW, DRAWING # BM-036, COPY ON FILE IN THE ENVIRONMENTAL MANAGEMENT OFFICE, FORT BLISS - Fort Bliss, 7th Cavalry Buildings, U.S. Army Air Defence Artillery Center & Fort Bliss, El Paso, El Paso County, TX

  19. LISA in the gravitational wave decade

    NASA Astrophysics Data System (ADS)

    Conklin, John; Cornish, Neil

    2015-04-01

    With the expected direct detection of gravitational waves in the second half of this decade by Advanced LIGO and pulsar timing arrays, and with the launch of LISA Pathfinder in the summer of this year, this can arguably be called the decade of gravitational waves. Low frequency gravitational waves in the mHz range, which can only be observed from space, provide the richest science and complement high frequency observatories on the ground. A space-based observatory will improve our understanding of the formation and growth of massive black holes, create a census of compact binary systems in the Milky Way, test general relativity in extreme conditions, and enable searches for new physics. LISA, by far the most mature concept for detecting gravitational waves from space, has consistently ranked among the nation's top priority large science missions. In 2013, ESA selected the science theme ``The Gravitational Universe'' for its third large mission, L3, under the Cosmic Visions Program, with a planned launch date of 2034. Recently, NASA has decided to join with ESA on the L3 mission as a junior partner. Both agencies formed a committee to advise them on the scientific and technological approaches for a space based gravitational wave observatory. The leading mission design, Evolved LISA or eLISA, is a slightly de-scoped version of the earlier LISA design. This talk will describe activities of the Gravitational Wave Science Interest Group (GWSIG) under the Physics of the Cosmos Program Analysis Group (PhysPAG), focusing on LISA technology development in both the U.S. and Europe, including the LISA Pathfinder mission.

  20. Free-Flight Experiments in LISA Pathfinder

    NASA Technical Reports Server (NTRS)

    Thorpe, J. I.; Cutler, C. J.; Hewitson, M.; Jennrich, O.; Maghami, P.; Paczkowski, S.; Russano, G.; Vitale, S.; Weber, W. J.

    2014-01-01

    The LISA Pathfinder mission will demonstrate the technology of drag-free test masses for use as inertial references in future space-based gravitational wave detectors. To accomplish this, the Pathfinder spacecraft will perform drag-free flight about a test mass while measuring the acceleration of this primary test mass relative to a second reference test mass. Because the reference test mass is contained within the same spacecraft, it is necessary to apply forces on it to maintain its position and attitude relative to the spacecraft. These forces are a potential source of acceleration noise in the LISA Pathfinder system that are not present in the full LISA configuration. While LISA Pathfinder has been designed to meet it's primary mission requirements in the presence of this noise, recent estimates suggest that the on-orbit performance may be limited by this 'suspension noise'. The drift-mode or free-flight experiments provide an opportunity to mitigate this noise source and further characterize the underlying disturbances that are of interest to the designers of LISA-like instruments. This article provides a high-level overview of these experiments and the methods under development to analyze the resulting data.

  1. Free-flight experiments in LISA Pathfinder

    NASA Astrophysics Data System (ADS)

    Armano, M.; Audley, H.; Auger, G.; Baird, J.; Binetruy, P.; Born, M.; Bortoluzzi, D.; Brandt, N.; Bursi, A.; Caleno, M.; Cavalleri, A.; Cesarini, A.; Cruise, M.; Cutler, C.; Danzmann, K.; Diepholz, I.; Dolesi, R.; Dunbar, N.; Ferraioli, L.; Ferroni, V.; Fitzsimons, E.; Freschi, M.; Gallegos, J.; García Marirrodriga, C.; Gerndt, R.; Gesa, LI; Gibert, F.; Giardini, D.; Giusteri, R.; Grimani, C.; Harrison, I.; Heinzel, G.; Hewitson, M.; Hollington, D.; Hueller, M.; Huesler, J.; Inchauspé, H.; Jennrich, O.; Jetzer, P.; Johlander, B.; Karnesis, N.; Kaune, B.; Korsakova, N.; Killow, C.; Lloro, I.; Maarschalkerweerd, R.; Madden, S.; Maghami, P.; Mance, D.; Martín, V.; Martin-Porqueras, F.; Mateos, I.; McNamara, P.; Mendes, J.; Mendes, L.; Moroni, A.; Nofrarias, M.; Paczkowski, S.; Perreur-Lloyd, M.; Petiteau, A.; Pivato, P.; Plagnol, E.; Prat, P.; Ragnit, U.; Ramos-Castro, J.; Reiche, J.; Romera Perez, J. A.; Robertson, D.; Rozemeijer, H.; Russano, G.; Sarra, P.; Schleicher, A.; Slutsky, J.; Sopuerta, C. F.; Sumner, T.; Texier, D.; Thorpe, J.; Trenkel, C.; Tu, H. B.; Vetrugno, D.; Vitale, S.; Wanner, G.; Ward, H.; Waschke, S.; Wass, P.; Wealthy, D.; Wen, S.; Weber, W.; Wittchen, A.; Zanoni, C.; Ziegler, T.; Zweifel, P.

    2015-05-01

    The LISA Pathfinder mission will demonstrate the technology of drag-free test masses for use as inertial references in future space-based gravitational wave detectors. To accomplish this, the Pathfinder spacecraft will perform drag-free flight about a test mass while measuring the acceleration of this primary test mass relative to a second reference test mass. Because the reference test mass is contained within the same spacecraft, it is necessary to apply forces on it to maintain its position and attitude relative to the spacecraft. These forces are a potential source of acceleration noise in the LISA Pathfinder system that are not present in the full LISA configuration. While LISA Pathfinder has been designed to meet it's primary mission requirements in the presence of this noise, recent estimates suggest that the on-orbit performance may be limited by this ‘suspension noise’. The drift-mode or free-flight experiments provide an opportunity to mitigate this noise source and further characterize the underlying disturbances that are of interest to the designers of LISA-like instruments. This article provides a high-level overview of these experiments and the methods under development to analyze the resulting data.

  2. LISACode: A scientific simulator of LISA

    NASA Astrophysics Data System (ADS)

    Petiteau, Antoine; Auger, Gérard; Halloin, Hubert; Jeannin, Olivier; Plagnol, Eric; Pireaux, Sophie; Regimbau, Tania; Vinet, Jean-Yves

    2008-01-01

    A new LISA simulator (LISACode) is presented. Its ambition is to achieve a new degree of sophistication allowing to map, as closely as possible, the impact of the different subsystems on the measurements. LISACode is not a detailed simulator at the engineering level but rather a tool whose purpose is to bridge the gap between the basic principles of LISA and a future, sophisticated end-to-end simulator. This is achieved by introducing, in a realistic manner, most of the ingredients that will influence LISA’s sensitivity as well as the application of TDI combinations. Many user-defined parameters allow the code to study different configurations of LISA thus helping to finalize the definition of the detector. Another important use of LISACode is in generating time-series for data analysis developments.

  3. LISA Parameter Estimation using Numerical Merger Waveforms

    NASA Technical Reports Server (NTRS)

    Thorpe, J. I.; McWilliams, S.; Baker, J.

    2008-01-01

    Coalescing supermassive black holes are expected to provide the strongest sources for gravitational radiation detected by LISA. Recent advances in numerical relativity provide a detailed description of the waveforms of such signals. We present a preliminary study of LISA's sensitivity to waveform parameters using a hybrid numerical/analytic waveform describing the coalescence of two equal-mass, nonspinning black holes. The Synthetic LISA software package is used to simulate the instrument response and the Fisher information matrix method is used to estimate errors in the waveform parameters. Initial results indicate that inclusion of the merger signal can significantly improve the precision of some parameter estimates. For example, the median parameter errors for an ensemble of systems with total redshifted mass of 10(exp 6) deg M solar mass at a redshift of z is approximately 1 were found to decrease by a factor of slightly more than two when the merger was included.

  4. Getting Astrophysical Information from LISA Data

    NASA Technical Reports Server (NTRS)

    Stebbins, R. T.; Bender, P. L.; Folkner, W. M.

    1997-01-01

    Gravitational wave signals from a large number of astrophysical sources will be present in the LISA data. Information about as many sources as possible must be estimated from time series of strain measurements. Several types of signals are expected to be present: simple periodic signals from relatively stable binary systems, chirped signals from coalescing binary systems, complex waveforms from highly relativistic binary systems, stochastic backgrounds from galactic and extragalactic binary systems and possibly stochastic backgrounds from the early Universe. The orbital motion of the LISA antenna will modulate the phase and amplitude of all these signals, except the isotropic backgrounds and thereby give information on the directions of sources. Here we describe a candidate process for disentangling the gravitational wave signals and estimating the relevant astrophysical parameters from one year of LISA data. Nearly all of the sources will be identified by searching with templates based on source parameters and directions.

  5. 7th Annual Systems Biology Symposium: Systems Biology and Engineering

    SciTech Connect

    Galitski, Timothy P.

    2008-04-01

    Systems biology recognizes the complex multi-scale organization of biological systems, from molecules to ecosystems. The International Symposium on Systems Biology has been hosted by the Institute for Systems Biology in Seattle, Washington, since 2002. The annual two-day event gathers the most influential researchers transforming biology into an integrative discipline investingating complex systems. Engineering and application of new technology is a central element of systems biology. Genome-scale, or very small-scale, biological questions drive the enigneering of new technologies, which enable new modes of experimentation and computational analysis, leading to new biological insights and questions. Concepts and analytical methods in engineering are now finding direct applications in biology. Therefore, the 2008 Symposium, funded in partnership with the Department of Energy, featured global leaders in "Systems Biology and Engineering."

  6. Observing the Dark Side of the Universe: the Laser Interferometer Space Antenna (LISA)

    NASA Astrophysics Data System (ADS)

    Prince, Thomas Allen; Binetruy, P.; Cornish, N.; Cutler, C.; Hogan, C.; Madau, P.; Nelemans, G.; Phinney, S.; Schutz, B.

    2009-01-01

    - For the LISA International Science Team: LISA is a joint NASA/ESA space mission designed to measure gravitational waves in the band from 0.1 mHz to 0.1 Hz, a band that is richly populated by strong sources of gravitational waves. Signals will come from a wide range of sources: merging massive black holes in galaxies at all distances; stellar-mass compact objects captured by massive black holes; ultra-compact Galactic binaries; and possibly other sources including relics of the Big Bang. These sources convey detailed information addressing a wide range of physics and astrophysics: the history of galaxies and black holes in the universe; general relativity and the behavior of spacetime; precision luminosity distances of sources at high redshift; the physics of dense matter and stellar remnants; and possibly new physics associated with events in the very early universe. We will survey the science goals of LISA and their impact on physics and astrophysics.

  7. Progress in interferometry for LISA at JPL

    NASA Astrophysics Data System (ADS)

    Spero, Robert; Bachman, Brian; de Vine, Glenn; Dickson, Jeffrey; Klipstein, William; Ozawa, Tetsuo; McKenzie, Kirk; Shaddock, Daniel; Robison, David; Sutton, Andrew; Ware, Brent

    2011-05-01

    Recent advances at JPL in experimentation and design for LISA interferometry include the demonstration of time delay interferometry using electronically separated end stations, a new arm-locking design with improved gain and stability, and progress in flight readiness of digital and analog electronics for phase measurements.

  8. LISA Pathfinder Science Operations Concept and Development

    NASA Astrophysics Data System (ADS)

    Fauste, Jorge; McNamara, Paul; Armano, Michele; Texier, Damien; Freschi, Marco

    LISA Pathfinder is the second of the ESA Small Missions for Advanced Research in Technology, is a dedicated technology demonstrator for the joint ESA/NASA Laser Interferometer Space Antenna (LISA) mission. LISA Pathfinder carries two payloads, the European provided LISA Technology Package (LTP) and the NASA provided Disturbance Reduction System (DRS). The ground segment for LPF in the operational configuration will consist of one ground track-ing station, Cebreros (Spain), the Mission Operations Centre (MOC) at ESOC (Darmstadt, Germany), the Science Technology Operations Centre (STOC) located at ESOC and ESAC (Madrid, Spain) and LTP and DRS teams. The Science Technology Operations Centre although initially a small entity compatible with the operational requirements for an ESA SMART, has evolved in complexity in the last few years containing most of the systems and interfaces included as part of a normal ESA Science Operations Centre. In order to maintain a reasonable cost approach for its development and operations, a general reuse philosophy from systems already tested in previous ESA missions and/or from industry has been applied for the design and operation concept of the LPF STOC. The present paper describes the current LPF STOC design and it foreseen operational concept, highlighting the general reuse and customization process carried out for each of their individual subsystems.

  9. Operational procedures for the LISA Technology Package

    NASA Astrophysics Data System (ADS)

    Armano, Michele

    The peculiar nature of the LISA Path-finder makes it unique and cornerstone a mission for risk assessment in view of LISA. The credible detection of Gravity Waves in space in the frame of ESA Cosmic Vision Plan and ESA/NASA Beyond Einsten program stands on the shoulders of LISA Path-finder. The effectiveness of the mission in the relatively short lifetime of the Pathfinder satellite strongly relies on a carefully written set of operational procedure. LISA Pathfinder will have a tight schedule to prove a list of technology goals. The link between pre-mission scientific analysis and operational phase is of paramount importance in this scenario. Moreover, the ability to tune measurement procedures and finely adjust the space experiment depends on the flexibility of the measurement master plan. We report on the activity of writing operational procedures as a way to bridge the mission into reality. Due to space limitations, we will mainly consider the roadmaps for the measurement of acceleration difference and cross-talk evaluation.

  10. In-flight Diagnostics in LISA Pathfinder

    NASA Astrophysics Data System (ADS)

    Lobo, A.; Nofrarias, M.; Ramos-Castro, J.; Sanjuan, J.; Conchillo, A.; Ortega, J. A.; Xirgu, X.; Araujo, H.; Boatella, C.; Chmeissani, M.; Grimani, C.; Puigdengoles, C.; Wass, P.; García-Berro, E.; García, S.; Martínez, L. M.; Montero, G.

    2006-11-01

    LISA PathFinder (LPF) will be flown with the objective to test in space key technologies for LISA. However its sensitivity goals are, for good reason, one order of magnitude less than those which LISA will have to meet, both in drag-free and optical metrology requirements, and in the observation frequency band. While the expected success of LPF will of course be of itself a major step forward to LISA, one might not forget that a further improvement by an order of magnitude in performance will still be needed. Clues for the last leap are to be derived from proper disentanglement of the various sources of noise which contribute to the total noise, as measured in flight during the PathFinder mission. This paper describes the principles, workings and requirements of one of the key tools to serve the above objective: the diagnostics subsystem. This consists in sets of temperature, magnetic field, and particle counter sensors, together with generators of controlled thermal and magnetic perturbations. At least during the commissioning phase, the latter will be used to identify feed-through coefficients between diagnostics sensor readings and associated actual noise contributions. A brief progress report of the current state of development of the diagnostics subsystem will be given as well.

  11. The Laser Interferometer Space Antenna (LISA)

    NASA Astrophysics Data System (ADS)

    Prince, Thomas Allen; LISA International Science Team

    2011-01-01

    LISA is a joint NASA/ESA space mission designed to measure gravitational waves in the band from 0.1 mHz to 0.1 Hz, a band that is richly populated by strong sources of gravitational waves. Signals will come from a wide range of sources: massive black holes merging in galaxies; compact objects captured by massive black holes; ultra-compact Galactic binaries; and possibly other sources such as relics of the Big Bang. These sources convey detailed information addressing a wide range of physics and astrophysics: the history of galaxies and black holes in the universe; general relativity; measurements of luminosity distances; the physics of dense matter and stellar remnants; and possibly new physics associated with events in the very early universe. The LISA mission uses laser metrology between three spacecraft separated by 5 million km to detect gravitational wave sources with very high sensitivity. We will describe the LISA mission and summarize its current status, including technology development and the upcoming LISA Pathfinder mission.

  12. Engineering the LISA Project: Systems Engineering Challenges

    NASA Technical Reports Server (NTRS)

    Evans, Jordan P.

    2006-01-01

    The Laser Interferometer Space Antenna (LISA) is a joint NASA/ESA mission to detect and measure gravitational waves with periods from 1 s to 10000 s. The systems engineering challenges of developing a giant interferometer, 5 million kilometers on a side, an: numerous. Some of the key challenges are presented in this paper. The organizational challenges imposed by sharing the engineering function between three centers (ESA ESTEC, NASA GSFC, and JPL) across nine time zones are addressed. The issues and approaches to allocation of the acceleration noise and measurement sensitivity budget terms across a traditionally decomposed system are discussed. Additionally, using LISA to detect gravitational waves for the first time presents significant data analysis challenges, many of which drive the project system design. The approach to understanding the implications of science data analysis on the system is also addressed.

  13. Mapping the Milky Way Galaxy with LISA

    NASA Technical Reports Server (NTRS)

    McKinnon, Jose A.; Littenberg, Tyson

    2012-01-01

    Gravitational wave detectors in the mHz band (such as the Laser Interferometer Space Antenna, or LISA) will observe thousands of compact binaries in the galaxy which can be used to better understand the structure of the Milky Way. To test the effectiveness of LISA to measure the distribution of the galaxy, we simulated the Close White Dwarf Binary (CWDB) gravitational wave sky using different models for the Milky Way. To do so, we have developed a galaxy density distribution modeling code based on the Markov Chain Monte Carlo method. The code uses different distributions to construct realizations of the galaxy. We then use the Fisher Information Matrix to estimate the variance and covariance of the recovered parameters for each detected CWDB. This is the first step toward characterizing the capabilities of space-based gravitational wave detectors to constrain models for galactic structure, such as the size and orientation of the bar in the center of the Milky Way

  14. Microthrust Propulsion of the LISA Mission

    NASA Technical Reports Server (NTRS)

    Ziemer, John K.; Merkowitz, Stephen M.

    2004-01-01

    We present the most recent propulsion requirements for the Laser Interferometer Space Antenna (LISA) Mission and describe potential microth ruster technology that can meet these requirements. LISA consists of three spacecraft in heliocentric orbits, forming a triangle with 5x l 0 (exp 6) km sides that are the arms of three Michelson-type interferometers. Reflective proof masses provide the reference surfaces at the end of the interferometer arms as part of the Gravitational Referenc e Sensor (GRS) designed to detect gravitational waves. The microthrus t propulsion system will be part of the Disturbance Reduction System (DRS), which is responsible for maintaining each spacecraft position w ithin approximately 10 nm around the proof masses. To provide the nec essary sensitivity, the GRS must not experience spurious acceleration s >15 (exp -10) m/ s(exp 2) in the 0.1 mHz to 1 Hz bandwidth, requiring precision formation flying and drag-free operation of the LISA spa cecraft. This leads to the following microthruster performance requir ements: a thrust range of 2-30 Micro N, a thrust resolution < 0.1 Mic ro N, and thrust noise <0.1 Hz(exp -1/2) over the LISA measurement bandwidth. The microthruster must provide this performance for 5 years c ontinuously, contain 10 years worth of propellant, and not disrupt th e science measurements. Potential microthruster technologies include Colloid, Field Emission Electric Propulsion (FEEP), and precision cold gas microthrusters. Each of these technologies is described in detai l with focus on the NASA microthruster development of the Busek Collo id Micro-Newton Thruster (CMNT).

  15. Relevance and feasibility of Diagnostics Subsystems in LISA PathFinder and LISA

    NASA Astrophysics Data System (ADS)

    Lobo, Alberto; Grimani, Catia; Canizares, Priscilla; Chmeissani, Mokhtar; Diaz-Aguilo, Marc; Conchillo, Aleix; Gesa, Lluis; Lloro, Ivan; Mateos, Ignacio; Nofrarias, Miquel; Ramos-Castro, Juan; Sanjuan, Josep; Sopuerta, Carlos

    LISA PathFinder will fly equipped with a Diagnostics Subsystem which includes: 1) a Radi-ation Monitor, providing almost real time charged particle counting and spectral resolution, 2) a thermal diagnostics set with high sensitivity temperature sensors and precision heaters, and 3) four fluxgate vector magnetometers plus a pair of induction coils. The role of this in-strumentation in LISA PathFinder is to provide the necessary tools to evaluate the effect of charging, temperature and magnetic fluctuations on the interferometer readout. The use of this is to understand how the mentioned fluctuations in the LTP (LISA Technology Package) can be modelled, then use the measured data to quantify their contribution to the overall LTP noise. In this presentation we will review the LPF Diagnostics System, recently delivered for LTP and spacecraft integration. We will also make some considerations on the meaning of the diagnostics for the future LISA, and propose lines of action to meet the more severe requirements which LISA will impose on environmental conditions.

  16. FOREWORD: The 7th Gravitational Wave Data Analysis Workshop, 17-19 December 2002, Kyoto, Japan

    NASA Astrophysics Data System (ADS)

    Kanda, Nobuyuki; Sasaki, Misao; Tagoshi, Hideyuki

    2003-09-01

    The 7th Gravitational Wave Data Analysis Workshop (GWDAW2002) was held at the International Institute for Advanced Studies (IIAS) in Kyoto, Japan, on 17-19 December 2002. The GWDAW series is one of the important international conferences supported by the Gravitational Wave International Committee (GWIC). The workshops have been held annually, and the topics covered range from data analyses for all kinds of gravitational wave detectors to theoretical issues on gravitational wave sources. This year's workshop consisted of seven categories of sessions: the status of detectors, space-based detectors, event search, detector characterization, coincidence of detectors and detector network analysis, new methods of analysis, and sources for advanced ground-based detectors. The year 2002 was an epoch-making year for gravitational wave detection experiments. Some of the large-scale ground-based laser interferometric detectors (LIGO, GEO and TAMA) entered their initial or developed stage of observation, performing scientific runs with durations of several weeks. As a result, many of the talks presented at the workshop were based on actual data taken from these experiments, and we were able to have more realistic discussions on gravitational wave detection. Furthermore, the successful operations of these laser interferometric detectors gave the gravitational wave community a strong motive to form a worldwide detector network, as practised by existing resonant-type detectors. In fact, there were reports on the simultaneous operation of five laser interferometric detectors, and a report on a plan for coincidence operations over a month. There were also reports on future space-based detectors and their source studies from aspects of the data analysis. Thanks to well-prepared talks and vivid discussions by the participants, the workshop was extremely fruitful. These proceedings contain refined and updated papers based on the talks given at the workshop and will provide readers of

  17. Measuring Massive Black Hole Binaries with LISA

    NASA Technical Reports Server (NTRS)

    Lang, Ryan N.; Hughes, Scott A.; Cornish, Neil J.

    2009-01-01

    The coalescence of two massive black holes produces gravitational waves (GWs) which can be detected by the space-based detector LISA. By measuring these waves, LISA can determine the various parameters which characterize the source. Measurements of the black hole masses and spins will provide information about the growth of black holes and their host galaxies over time. Measurements of a source's sky position and distance may help astronomers identify an electromagnetic counterpart to the GW event. The counterpart's redshift, combined with the GW-measured luminosity distance, can then be used to measure the Hubble constant and the dark energy parameter $w$. Because the potential science output is so high, it is useful to know in advance how well LISA can measure source parameters for a wide range of binaries. We calculate expected parameter estimation errors using the well-known Fisher matrix method. Our waveform model includes the physics of spin precession, as well as subleading harmonics. When these higher-order effects are not included, strong degeneracies between some parameters cause them to be poorly determined by a GW measurement. When precession and subleading harmonics are properly included, the degeneracies are broken, reducing parameter errors by one to several orders of magnitude.

  18. Data Analysis for the LISA Pathfinder Mission

    NASA Technical Reports Server (NTRS)

    Thorpe, James Ira

    2009-01-01

    The LTP (LISA Technology Package) is the core part of the Laser Interferometer Space Antenna (LISA) Pathfinder mission. The main goal of the mission is to study the sources of any disturbances that perturb the motion of the freely-falling test masses from their geodesic trajectories as well as 10 test various technologies needed for LISA. The LTP experiment is designed as a sequence of experimental runs in which the performance of the instrument is studied and characterized under different operating conditions. In order to best optimize subsequent experimental runs, each run must be promptly analysed to ensure that the following ones make best use of the available knowledge of the instrument ' In order to do this, all analyses must be designed and tested in advance of the mission and have sufficient built-in flexibility to account for unexpected results or behaviour. To support this activity, a robust and flexible data analysis software package is also required. This poster presents two of the main components that make up the data analysis effort: the data analysis software and the mock-data challenges used to validate analysis procedures and experiment designs.

  19. Bayesian model selection for LISA pathfinder

    NASA Astrophysics Data System (ADS)

    Karnesis, Nikolaos; Nofrarias, Miquel; Sopuerta, Carlos F.; Gibert, Ferran; Armano, Michele; Audley, Heather; Congedo, Giuseppe; Diepholz, Ingo; Ferraioli, Luigi; Hewitson, Martin; Hueller, Mauro; Korsakova, Natalia; McNamara, Paul W.; Plagnol, Eric; Vitale, Stefano

    2014-03-01

    The main goal of the LISA Pathfinder (LPF) mission is to fully characterize the acceleration noise models and to test key technologies for future space-based gravitational-wave observatories similar to the eLISA concept. The data analysis team has developed complex three-dimensional models of the LISA Technology Package (LTP) experiment onboard the LPF. These models are used for simulations, but, more importantly, they will be used for parameter estimation purposes during flight operations. One of the tasks of the data analysis team is to identify the physical effects that contribute significantly to the properties of the instrument noise. A way of approaching this problem is to recover the essential parameters of a LTP model fitting the data. Thus, we want to define the simplest model that efficiently explains the observations. To do so, adopting a Bayesian framework, one has to estimate the so-called Bayes factor between two competing models. In our analysis, we use three main different methods to estimate it: the reversible jump Markov chain Monte Carlo method, the Schwarz criterion, and the Laplace approximation. They are applied to simulated LPF experiments in which the most probable LTP model that explains the observations is recovered. The same type of analysis presented in this paper is expected to be followed during flight operations. Moreover, the correlation of the output of the aforementioned methods with the design of the experiment is explored.

  20. 7th Annual Symposium on Clinical and Pharmaceutical Solutions through Analysis.

    PubMed

    Zhang, Tianyi Tee; Wang, Li; Weng, Naidong; Dong, Kelly; Valaskovic, Gary; Lee, Mike

    2016-10-01

    7th Annual Symposium on Clinical & Pharmaceutical Solutions through Analysis, Renaissance Shanghai Pudong Hotel, Shanghai, China, 20-23 April 2016 The 7th Annual Shanghai Symposium on Innovative Approaches to Reduce Attrition and Predict Clinical Outcomes (CPSA Shanghai 2016) was held on 20-23 April 2016 in Renaissance Shanghai Pudong Hotel, Shanghai, China. The meeting was featured with highly interactive events including diversified symposia, round table discussions, workshops, poster sessions and conference awards. There were over 220 participants from more than ten countries, with 61 oral presentations and 29 posters presented. In addition, the meeting included one preconference workshop and three joint sessions held with bioanalytical experts from local communities.

  1. Milli-Hertz Gravitational Waves: LISA and LISA PathFinder

    NASA Astrophysics Data System (ADS)

    Araújo, H.; Cañizares, P.; Chmeissani, M.; Conchillo, A.; Díaz-Aguiló, M.; García-Berro, E.; Gesa, L.; Gibert, F.; Grimani, C.; Hajdas, W.; Hollington, D.; Lloro, I.; Lobo, A.; Mateos, I.; Nofrarias, M.; Puigdengoles, C.; Ramos-Castro, J.; Sanjuán, J.; Sopuerta, Cf; Wass, P.

    2011-09-01

    Ground based GW detectors are limited at their lower frequency band (1-10 Hz) by settlement gravity gradients and seismic noise, and their sensitivity peaks at around 100 Hz. Sources in this band are mostly short duration signals, and their rates uncertain. Going down to milli-Hertz frequencies significantly increases the number and types of available sources. LISA was planned with the idea to explore a likely richer region of the GW spectrum, beyond that accessible to ground detectors; the latter are however expected to produce the first GW observations. In this paper I will present the main LISA concepts; in particular, emphasis will be placed on LISAPathFinder, the ESA precursor of LISA, in which our research group in Barcelona is heavily involved.

  2. LISA and LISA PathFinder, the endeavour to detect low frequency GWs

    NASA Astrophysics Data System (ADS)

    Araújo, H.; Boatella, C.; Chmeissani, M.; Conchillo, A.; García-Berro, E.; Grimani, C.; Hajdas, W.; Lobo, A.; Martínez, Ll; Nofrarias, M.; Ortega, J. A.; Puigdengoles, C.; Ramos-Castro, J.; Sanjuán, J.; Wass, P.; Xirgu, X.

    2007-05-01

    This is a review about LISA and its technology demonstrator, LISAPathFinder. We first describe the conceptual problems which need to be overcome in order to set up a working interferometric detector of low frequency Gravitational Waves (GW), then summarise the solutions to them as currently conceived by the LISA mission team. This will show that some of these solutions require new technological abilities which are still under development, and which need proper test before being fully implemented. LISAPathFinder (LPF) is the the testbed for such technologies. The final part of the paper will address the ideas and concepts behind the PathFinder as well as their impact on LISA.

  3. Overview and research agenda arising from the 7th World Workshop on Oral Health and Disease in AIDS.

    PubMed

    Tappuni, A R; Shiboski, C

    2016-04-01

    The Research Agenda generated by the 7th World Workshop on Oral Health and Disease in AIDS (WW7) is delivered in this paper. Panels of international experts presided over nine workshops that constituted the conference held in November 2014 in Hyderabad, India. The main goal of the Workshop was to bring together clinician and scientists interested in the subject to debate with world-wide perspectives current issues related to the oral manifestations in HIV/AIDS. The workshops were structured around three themes; basic science, clinical/translational science and social science and were attended by 135 participants from 31 countries. The research questions debated at the workshops are presented in nine consensus papers published in this issue and are summarised in this paper along with an outline of the identified research needs in the field.

  4. From exobiology to cosmobiology at LISA and elsewhere.

    PubMed

    Raulin, F

    1998-06-01

    Since the emergence of Exobiology, back to the l960ties, this field drastically increased and, although differently named, is today a largely recognized scientific domain of wild interdisciplinarity. It includes not only the search for extraterrestrial living Systems, in particular by direct exploration of planetary bodies and studies of extraterrestrial materials, but also the study on the origins of life on Earth and, in connection to this field, the study of extraterrestrial organic chemistry. The exobiology programmes currently developed at LISA are related to this last aspect. They include the study of prebiotic-like chemistry in the gas and solid phases, based on laboratory simulation experiments, theoretical modeling and future in situ measurements in Titan's atmosphere and in cometary nuclei. A national program of exobiology, coordinated by LISA is under development in France, it covers many of the various aspects of Exobiology, including the study of life in extreme environments, as a reference tool for extraterrestrial life, the study of the primitive environment of the Earth, of the organic chemistry in comets and on Titan, of Mars and Europa and even of extrasolar planets as potential niches for extraterrestrial living systems, associated to the determination of the electromagnetic signatures of life. In parallel to this general program, a proposal for a large simulation chamber to be used as a national facility in particular to simulate the organic chemistry in various planetary environments, and in the interstellar medium, is under preparation. International cooperations linked to these programmes, in particular in the frame of the development of an exobiology facility on the International Space Station, would be of crucial interest.

  5. Conceptions of Mathematics in Different Ability and Achievement Groups among 7th Grade Students

    ERIC Educational Resources Information Center

    Lepmann, Lea; Afanasjev, Juri

    2005-01-01

    This report deals with 7th grade pupils' conceptions of mathematics, its learning and teaching. The report focuses on the identification and comparison of views expressed by pupil groups of different mathematical ability and achievement. The analysis is based on the results of the ability tests, subject tests and a questionnaire conducted among…

  6. Effects of Concept Cartoons on Mathematics Self-Efficacy of 7th Grade Students

    ERIC Educational Resources Information Center

    Sengul, Sare

    2011-01-01

    The purpose of this research is to determine the effect of concept cartoons on the students' perception of their levels of self-efficacy towards mathematics. The research has been designed as the pre-test post-test with quasi experimental control group. The research participants are composed of 94 7th grade students attending an elementary school…

  7. The Effect of Learning Integers Using Cartoons on 7th Grade Students' Attitude to Mathematics

    ERIC Educational Resources Information Center

    Sengül, Sare; Dereli, Mehtap

    2013-01-01

    The purpose of this research is to investigate the effect on students' attitudes toward mathematics when cartoons are used in teaching integers. The research was designed in the form of a pre-test and post-test with a quasi experimental control group. The research participant group was composed of sixty-one (61) 7th grade students attending an…

  8. Opinions of 7th Grade Students about Enriched Educational Practices in the Scope of Science Course

    ERIC Educational Resources Information Center

    Idin, Sahin; Aydogdu, Cemil

    2016-01-01

    The purpose of this research was to determine the opinions of the students about 7th grade science courses carried out with enriched educational practices. The research was conducted throughout fall semester of 2014-2015 academic year in the scope of Systems within our Body Unit (SBU), Force and Motion Unit (FMU), and Electric within our Lives…

  9. Medieval Armenian Costumes: A History of the Armenians from the 7th-14th Centuries.

    ERIC Educational Resources Information Center

    Soghikian, Juanita Will

    The booklet contains illustrations of 40 medieval Armenian costumes based upon statues and paintings of the 7th through the 14th centuries. Part of a series of seven instructional materials dealing with the history and culture of Armenian Americans, the booklet also provides a discussion of Armenian history and detailed descriptions of each…

  10. Activities Using The State of the World Atlas, 7th Edition

    ERIC Educational Resources Information Center

    Hegelbach, Peter; Haakenson, Dean; Starbird, Caroline

    2004-01-01

    This book is designed to accompany The State of the World Atlas, 7th Edition. The State of the World Atlas and this workbook provide a frame of reference for the changing pattern of world events. Students will become familiar with different statistical representations of the world, from birth rates to HIV/AIDS infections rates; from world…

  11. A noise simulator for eLISA: Migrating LISA Pathfinder knowledge to the eLISA mission

    NASA Astrophysics Data System (ADS)

    Armano, M.; Audley, H.; Auger, G.; Baird, J.; Binetruy, P.; Born, M.; Bortoluzzi, D.; Brandt, N.; Bursi, A.; Caleno, M.; Cavalleri, A.; Cesarini, A.; Cruise, M.; Danzmann, K.; Diepholz, I.; Dolesi, R.; Dunbar, N.; Ferraioli, L.; Ferroni, V.; Fitzsimons, E.; Freschi, M.; Gallegos, J.; García Marirrodriga, C.; Gerndt, R.; Gesa, L. I.; Gibert, F.; Giardini, D.; Giusteri, R.; Grimani, C.; Harrison, I.; Heinzel, G.; Hewitson, M.; Hollington, D.; Hueller, M.; Huesler, J.; Inchauspé, H.; Jennrich, O.; Jetzer, P.; Johlander, B.; Karnesis, N.; Kaune, B.; Korsakova, N.; Killow, C.; Lloro, I.; Maarschalkerweerd, R.; Madden, S.; Mance, D.; Martín, V.; Martin-Porqueras, F.; Mateos, I.; McNamara, P.; Mendes, J.; Mendes, L.; Moroni, A.; Nofrarias, M.; Paczkowski, S.; Perreur-Lloyd, M.; Petiteau, A.; Pivato, P.; Plagnol, E.; Prat, P.; Ragnit, U.; Ramos-Castro, J.; Reiche, J.; Romera Perez, J. A.; Robertson, D.; Rozemeijer, H.; Russano, G.; Sarra, P.; Schleicher, A.; Slutsky, J.; Sopuerta, C. F.; Sumner, T.; Texier, D.; Thorpe, J.; Trenkel, C.; Tu, H. B.; Vetrugno, D.; Vitale, S.; Wanner, G.; Ward, H.; Waschke, S.; Wass, P.; Wealthy, D.; Wen, S.; Weber, W.; Wittchen, A.; Zanoni, C.; Ziegler, T.; Zweifel, P.

    2015-05-01

    We present a new technical simulator for the eLISA mission, based on state space modeling techniques and developed in MATLAB. This simulator computes the coordinate and velocity over time of each body involved in the constellation, i.e. the spacecraft and its test masses, taking into account the different disturbances and actuations. This allows studying the contribution of instrumental noises and system imperfections on the residual acceleration applied on the TMs, the latter reflecting the performance of the achieved free-fall along the sensitive axis. A preliminary version of the results is presented.

  12. 7th International Workshop on the Identification of Transcribed Sequences. Beyond the Identification of Transcribed Sequences

    SciTech Connect

    Gardner, Kathleen

    1997-11-19

    The Seventh Annual Human Genome Conference: Beyond the Identification of Transcribed Sequences (BITS) was held November 16-19, 1997 at the Asilomar Conference Center in Monterey, California. The format for the meeting was a combination of oral presentations, group discussions and poster sessions. The original workshop was held to discuss methodologies for the identification of transcribed sequences in mammalian genomes. Over the years, the focus of the workshops has gradually shifted towards functional analysis, with the most dramatic change in emphasis at this meeting, as reflected in the modest change in the workshop title. Topics presented and discussed included: (1) large scale expression and mutational analysis in yeast, C. elegans, Drosophila and zebrafish, (2) comparative mapping of zebrafish, chicken and Fugu; (3) functional analysis in mouse using promoter traps, mutational analysis of biochemical pathways, and Cre/lox constructs; (4) construction of 5 foot end and complete cDNA libraries; (5) expression analysis in mammalian organisms by array screening and differential display; (6) genome organization as determined by detailed transcriptional mapping and genomic sequence analysis; (7) analysis of genomic sequence, including gene and regulatory sequence predictions, annotation of genomic sequence, development of expression databases and verification of sequence analysis predictions; and (8) structural/functional relationships as determined by RNA secondary structure analysis and evolutionary conservation of non-coding sequences.

  13. Shallow-Lever Centers in Semiconductors - Proceedings of the 7th International Conference

    NASA Astrophysics Data System (ADS)

    Ammerlaan, C. A. J.; Pajot, B.

    1997-04-01

    The Table of Contents for the book is as follows: * Resonant Polaron Effect of Shallow Indium Donors in CdTe * Magnetic Resonance of Dopants and Defects in GaN-Based Materials and Devices * Some Aspects of the Hydrogen-Dopant Interactions in Compound Semiconductors * Shallow Electronic Traps Associated with Hydrogen Complexes in Crystalline Silicon * Shallow-Level Donor States of Strong and Weak Localization * Optical Spectroscopy of Shallow States in GaAs/AlGaAs Quantum Wells * Negative Donor Centers and Donor-Bound Exciton Complexes in Two-Dimensional Systems in a Magnetic Field * The State of the Art of n- and p-Type Doping in II-VI Semiconductors Heterostructures * Carbon Doping of III-V Semiconductors by Ion Implantation * Passivation of Shallow Dopants in II-VI Semiconductors * Zeeman Spectroscopy of Neutral Copper and a Copper Related Acceptor in Germanium * Carrier Scattering by Neutral Double Donors and Acceptors: Theory and Experiment * Donors and Impurity-Bound Phonons in Nitrogen-Doped ZnSe * The Electronic Structure of the Shallow Boron Acceptor in 6H-SiC: A Pulsed EPR/ENDOR Study at 95 GHz * Boron-Related Infrared Absorption in Diamond * Excited States of the Vacancy in Diamond: Shallow States of a Deep Defect * Is H Passivating the Mg Acceptor Bond-Centred in InP:Mg and Antibonded in GaAs:Mg? * Local Vibrational Modes of Se-H Complexes in AlSb * First PAC Studies on the Hydrogen Diffusion in III-V Semiconductors * Theory of Nonradiative Transition of Bistability Center and Application to DX-Center in AlxGa1-xAs * The New Shallow Thermal Donor in Al-Doped Silicon: Formation Kinetics and Metastability Mechanisms * Far-Infrared Spectroscopy Based on Specific Properties of Shallow-Level Centers in Bulk and 2D Semiconductor Structures * Exchange-Correlation Effects in the Hole Band Structure of p-Type δ-Doping Quantum Wells and Superlattices * Shallow Donor in Spherical Quantum Antidots * Recombination Processes in Indium Doped CdMnTe/CdTe Multiple Quantum Well Structures Grown by MBE * Shallow Centers in Heavily Doped Silicon Quantum Wells * Optically Detected Resonance Spectroscopy of III-V and II-VI Quantum Wells * Shallow Thermal Donor Defects in Silicon * Pressure Dependence of Se Absorption Lines in AlSb * Fine Structure in the Magnetic Resonance of Single Acceptors in Silicon * Far-Infrared Photoconductivity and Photoluminescence of Beryllium in Gallium Arsenide * Shift of Photoluminescence Peak in Highly Self-Compensated Ge-Doped GaAs * Electron-Phonon Coupling in a Delta-Doped n-i-p Structure in GaAs * Group-III and Group-II Quasi-Deep Impurities in Silicon Carbide: Electron Paramagnetic Resonance and Optically Detected Magnetic Resonance Studies * Resonance Acceptor States in Uniaxially Strained Semiconductors * Donor-Related Infrared-Absorption Spectra of GaAs-(Ga, Al)As Quantum Wells * Electrical Properties of Shallow Donor Centers Formed Due to Oxygen Interaction with Chemically Active Impurities in Heat-Treated Silicon * Fine Structure and Higher Lying Transitions of Er3+ in 4H and 6H SiC * Mechanism for the Enhanced Dissociation of C-H Complexes in GaAs * Bistability and Metastability of Hydrogen in Si * EPR of Aluminum-Aluminum Interstitial Pair in Silicon * Magnetic Order of Shallow Acceptor Centres in Semiconductors (InSb:Mn) * Luminescence and DLTS Study of Photonuclear Transmutation Doped (PND) Gallium Arsenide * Photoluminescence of Deformed Bulk Crystals of Si-Ge Alloy * Di-Oxygen Complex in Silicon: Some New Characteristic Features * Reactions of Interstitial Iron with Shallow Acceptors in Silicon * The 819.8 meV Photoluminescence Band in Copper Doped Silicon * Zeeman Spectroscopy of Aluminium in Germanium * Microscopic Studies of the Hydrogen Passivation in n-Type Silicon: A New Application of the 73As γ-e- PAC Technique * Shallow Donor Solubility Mechanism: Tellurium in GaAs * Energy Levels of Shallow Donor Pairs and Thermal Double Donors in Silicon * Boron Neutralization by Hydrogen in Epitaxial Si Films Grown at Very Low Temperature (≤ 200°C) * An Oxygen-Related 1-Platinum Shallow-Level Center in n- and p-Type Silicon * Excitonic Enhanced Optical Gain for Wide-Gap Laser Diodes Using Impurity States * Multistep Changes of Defect Electrical Activity Due to Interaction with Hydrogen * Annealing Behavior of Crystalline Silicon Heavily Implanted with Oxygen at Low Temperature * Intracenter Population Inversion of Strain-Split Acceptor Levels in Ge * Field Ionization of Shallow Impurities at Random Potential * Magnetoluminescence Spectra Associated to Acceptors in GaAs-(Ga, Al)As Superlattices * Magnetic-Field Effects on the Optical Absorption Spectra Associated with Shallow Impurities in Quantum Wells * Shallow Level Excitations of Transition Metal and Rare Earth Element Isoelectronic Impurities in II-VI and III-V Semiconductors * Local States Band Induced by B-Delta Doping in Si/SiGe/Si Quantum Wells * Selfinterstitial and Selfinterstitial-Related Defects in Irradiated p-Type Silicon * Luminescence of Excitons Bound to Complexes of Impurities and Defects in Irradiated Germanium * On the Role of Closely Placed Excited States in the Anomalous Behaviour of the Spin System Fe3+ in GaAs * Optical Studies of Be Acceptors Confined in Flat Islands at GaAs/GaAlAs Quantum-Well Interfaces * Ab Initio Study of Group V Elements in Amorphous Silicon * Influence of Intrinsic Defects and S Substitutions on Electrical Properties of Chalcopyrite CuInS2 Compounds * Piezospectroscopy of Antimony in Germanium * Impurity Centre in a Single Quantum Well in the Presence of a Strong Magnetic Field * Electron Paramagnetic Resonance Study of a High Concentration Shallow Level Pt Defect in Silicon with Effective Mass Like Properties * Theory of Hydrogen Single Passivated Substitutional Sulphur Double Donor in Si * Diffusion of Cadmium into Gallium Arsenide Investigated by Means of SIMS and Spreading-Resistance Profiling * Size Effect of Shallow Acceptor Impurities on Formation Process of Iron-Acceptor Pairs in Silicon * Hydrogen Passivation of Multicrystalline Silicon Solar Cells by Plasma Deposition of Silicon Nitride * The Interaction between Boron Acceptors in Silicon and Carbon and Self-Interstitials * Excitons Bound at Acceptor Complexes in p-Type GaAs/AlGaAs Quantum Wells

  14. Group International Travel to World Round Table Conference on Sintering (7th)

    DTIC Science & Technology

    1990-09-01

    invited paper 9. Professor Egon Matijevic Clarkson University Author of invited paper 10. Professor Randall German RPI Author of invited paper 11...350.00 University of Florida 9. D. Lynn Johnson $350.00 Northwestern University 10. Egon Matijevic $350.00 Clarkson University 11. Randall German $350.00

  15. A Bayesian-style approach to estimating LISA science capability

    NASA Astrophysics Data System (ADS)

    Baker, John; Marsat, Sylvain

    2017-01-01

    A full understanding of LISA's science capability will require accurate models of incident waveform signals and the instrumental response. While Fisher matrix analysis is useful for some estimates, a Bayesian characterization of simulated probability distributions is needed for understanding important cases at the limit of LISA's capability. We apply fast analysis algorithms enabling accurate treatment using EOB waveforms with relevant higher modes and the full-featured LISA response to study these aspects of LISA science capability. Supported by NASA grant 11-ATP-046.

  16. The pLISA project in ASTERICS

    NASA Astrophysics Data System (ADS)

    De Bonis, Giulia; Bozza, Cristiano

    2017-03-01

    In the framework of Horizon 2020, the European Commission approved the ASTERICS initiative (ASTronomy ESFRI and Research Infrastructure CluSter) to collect knowledge and experiences from astronomy, astrophysics and particle physics and foster synergies among existing research infrastructures and scientific communities, hence paving the way for future ones. ASTERICS aims at producing a common set of tools and strategies to be applied in Astronomy ESFRI facilities. In particular, it will target the so-called multi-messenger approach to combine information from optical and radio telescopes, photon counters and neutrino telescopes. pLISA is a software tool under development in ASTERICS to help and promote machine learning as a unified approach to multivariate analysis of astrophysical data and signals. The library will offer a collection of classification parameters, estimators, classes and methods to be linked and used in reconstruction programs (and possibly also extended), to characterize events in terms of particle identification and energy. The pLISA library aims at offering the software infras tructure for applications developed inside different experiments and has been designed with an effort to extrapolate general, physics-related estimators from the specific features of the data model related to each particular experiment. pLISA is oriented towards parallel computing architectures, with awareness of the opportunity of using GPUs as accelerators demanding specifically optimized algorithms and to reduce the costs of pro cessing hardware requested for the reconstruction tasks. Indeed, a fast (ideally, real-time) reconstruction can open the way for the development or improvement of alert systems, typically required by multi-messenger search programmes among the different experi mental facilities involved in ASTERICS.

  17. The LISA Pathfinder DMU and Radiation Monitor

    NASA Astrophysics Data System (ADS)

    Canizares, P.; Chmeissani, M.; Conchillo, A.; Diaz–Aguiló, M.; García-Berro, E.; Gesa, L.; Gibert, F.; Grimani, C.; Lloro, I.; Lobo, A.; Mateos, I.; Nofrarias, M.; Ramos-Castro, J.; Sanjuán, J.; Sopuerta, Carlos F.; Araújo, H. M.; Wass, P.

    2011-05-01

    The LISA Pathfinder DMU (Data Management Unit) flight model was formally accepted by ESA and ASD on 11 February 2010, after all hardware and software tests had been successfully completed. The diagnostics items are scheduled to be delivered by the end of 2010. In this paper, we review the requirements and performance of this instrumentation, specially focusing on the Radiation Monitor and the DMU, as well as the status of their programmed use during mission operations, on which work is ongoing at the time of writing.

  18. TOPICAL REVIEW: LISA technology and instrumentation

    NASA Astrophysics Data System (ADS)

    Jennrich, O.

    2009-08-01

    This article reviews the present status of the technology and instrumentation for the joint ESA/NASA gravitational wave detector LISA. It briefly describes the measurement principle and the mission architecture including the resulting sensitivity before focussing on a description of the main payload items, such as the interferometric measurement system, comprising the optical system with the optical bench and the telescope, the laser system and the phase measurement system, and the disturbance reduction system with the inertial sensor, the charge control system and the micropropulsion system. The review touches upon the requirements for the different subsystems that need to be fulfilled to obtain the overall sensitivity.

  19. Coherent observations of gravitational radiation with LISA and gLISA

    NASA Astrophysics Data System (ADS)

    Tinto, Massimo; de Araujo, José C. N.

    2016-10-01

    The geosynchronous Laser Interferometer Space Antenna (gLISA) is a space-based gravitational wave (GW) mission that, for the past 5 years, has been under joint study at the Jet Propulsion Laboratory; Stanford University; the National Institute for Space Research (I.N.P.E., Brazil); and Space Systems Loral. If flown at the same time as the LISA mission, the two arrays will deliver a joint sensitivity that accounts for the best performance of both missions in their respective parts of the millihertz band. This simultaneous operation will result in an optimally combined sensitivity curve that is "white" from about 3 ×10-3 Hz to 1 Hz, making the two antennas capable of detecting, with high signal-to-noise ratios (SNRs), coalescing black-hole binaries (BHBs) with masses in the range (10 -1 08)M⊙ . Their ability of jointly tracking, with enhanced SNR, signals similar to that observed by the Advanced Laser Interferometer Gravitational Wave Observatory (aLIGO) on September 14, 2015 (the GW150914 event) will result in a larger number of observable small-mass binary black holes and an improved precision of the parameters characterizing these sources. Together, LISA, gLISA and aLIGO will cover, with good sensitivity, the (10-4-1 03) Hz frequency band.

  20. LISA Beyond Einstein: From the Big Bang to Black Holes. LISA Technology Development at GSFC

    NASA Technical Reports Server (NTRS)

    Thorpe, James Ira

    2008-01-01

    This viewgraph presentation reviews the work that has been ongoing at the Goddard Space Flight Center (GSFC) in the development of the technology to be used in the Laser Interferometer Space Antenna (LISA) spacecrafts. The prime focus of LISA technology development efforts at NASA/GSFC has been in LISA interferometry. Specifically efforts have been made in the area of laser frequency noise mitigation. Laser frequency noise is addressed through a combination of stabilization and common-mode rejection. Current plans call for two stages of stabilization, pre-stabilization to a local frequency reference and further stabilization using the constellation as a frequency reference. In order for these techniques to be used simultaneously, the pre-stabilization step must provide an adjustable frequency offset. This presentation reports on a modification to the standard modulation/demodulation technique used to stabilize to optical cavities that generates a frequency-tunable reference from a fixed length cavity. This technique requires no modifications to the cavity itself and only minor modifications to the components. The measured noise performance and dynamic range of the laboratory prototype meet the LISA requirements.

  1. Detection of Micrometeoroids with LISA Pathfinder

    NASA Astrophysics Data System (ADS)

    Thorpe, Ira; Littenberg, Tyson; Janchez, Diego; Baker, John; The LISA Pathfinder Team Team

    2017-01-01

    The LISA Pathfinder mission (LPF), a joint ESA/NASA technology demonstration mission currently operating at the Sun-Earth L1 point, contains the most precise accelerometry system ever flown. Analysis suggests that LPF should have sufficient sensitivity to detect impacts of small micrometeoroids and dust through their transfer of momentum to the spacecraft. Moreover, LPF's ability to fully resolve both the linear and angular momentum transfer in three dimensions allows a magnitude, direction, and location to be estimated for each impact. We present preliminary results from a systematic search of the LISA Pathfinder data for such impacts and discuss the prospects for using these and future results to inform models of the formation and evolution of dust populations in the inner solar system. These models have wide applicability to both pure and applied space science, ranging from the physics of planet formation and dynamics of minor Solar System bodies to estimates of the micrometeorite hazard for future spacecraft. 2017 NASA Science Innovation Fund.

  2. Optical testbed for the LISA phasemeter

    NASA Astrophysics Data System (ADS)

    Schwarze, T. S.; Fernández Barranco, G.; Penkert, D.; Gerberding, O.; Heinzel, G.; Danzmann, K.

    2016-05-01

    The planned spaceborne gravitational wave detector LISA will allow the detection of gravitational waves at frequencies between 0.1 mHz and 1 Hz. A breadboard model for the metrology system aka the phasemeter was developed in the scope of an ESA technology development project by a collaboration between the Albert Einstein Institute, the Technical University of Denmark and the Danish industry partner Axcon Aps. It in particular provides the electronic readout of the main interferometer phases besides auxiliary functions. These include clock noise transfer, ADC pilot tone correction, inter-satellite ranging and data transfer. Besides in LISA, the phasemeter can also be applied in future satellite geodesy missions. Here we show the planning and advances in the implementation of an optical testbed for the full metrology chain. It is based on an ultra-stable hexagonal optical bench. This bench allows the generation of three unequal heterodyne beatnotes with a zero phase combination, thus providing the possibility to probe the phase readout for non-linearities in an optical three signal test. Additionally, the utilization of three independent phasemeters will allow the testing of the auxiliary functions. Once working, components can individually be replaced with flight-qualified hardware in this setup.

  3. Optical Bench for LISA-like missions

    NASA Astrophysics Data System (ADS)

    Mueller, Guido

    The detection of B-modes in the μ-Wave background has rattled the scientific community and further enhanced the large scientific interest in gravitational waves and gravitational wave astronomy. The first direct detection of gravitational waves by Advanced LIGO and maybe also by pulsar timing arrays in the second half of this decade will be another watershed event which will start a new era in astronomy and astrophysics. However, the holy grail of gravitational wave astronomy will be opened by a LISA-like mission. Only space provides the environment that allows to cover the signal-rich mHz frequency range where we expect to see gravitational waves from massive black hole mergers, compact galactic binaries, and many other sources. All mature concepts use laser interferometry between free falling test masses separated by millions of km. The central piece in all these concepts is a stable optical bench which is used to prepare and exchange the laser beams between the different arms. It has always been assumed that the base material for the optical bench has to be one of the ultra-low expansion glasses such as Zerodur or ULE to meet the pm/#Hz stability requirements. This very conservative approach was a reflection of the state-of-the-art in frequency stabilization experiments which used optical reference cavities in the early ‘90s. It is not surprising that the LISA pathfinder (LPF) uses also an all Zerodur bench where each optical component is precision bonded to the bench using hydroxide bonding, a nonreversible bonding technique. The manufacturing of this bench was a very time consuming one-mirror-a-day effort and was one of the highest risk items in terms of schedule and cost. The original LISA design uses the same approach except that the LISA bench is far more complex than the LPF bench and manufacturing of the required 10+ benches, six flight units and at least four pre-flight models and spares, will be even more time consuming and expensive. We question the

  4. [Review of WHO Expert Committee on Leprosy 8th report, --comparison to 7th report].

    PubMed

    Kitajima, Shinichi; En, Junichiro; Kitajima, Shiori; Barua, Sumana; Goto, Masamichi

    2014-03-01

    In 2012 the WHO Expert Committee on Leprosy published its 8th report, 14 years after the publication of its 7th report in 1998. This report, the first since the leprosy reduction goal was met in 2000, highlights key points such as improvements in the quality of various services available to patients and the efforts of individuals and societies, in addition to medical progress in diagnosis and treatment. This review will mainly describe the changes made since the 7th report. Some of the main modifications are the deletion of single lesion paucibacillary type, elongated treatment of patients with high bacterial indices, the introduction of promising new drugs, and a shift from reducing the statistical number of patients to a new target for disability prevention.

  5. 16. TWO HEAD GATES ABOUT 500 FEET NORTH OF 7TH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. TWO HEAD GATES ABOUT 500 FEET NORTH OF 7TH AVENUE (SECTION 35). - Highline Canal, Sand Creek Lateral, Beginning at intersection of Peoria Street & Highline Canal in Arapahoe County (City of Aurora), Sand Creek lateral Extends 15 miles Northerly through Araphoe County, City & County of Denver, & Adams County to its end point, approximately 1/4 mile Southest of intersectioin of D Street & Ninth Avenue in Adams County (Rocky Mountain Arsenal, Commerce City Vicinity), Commerce City, Adams County, CO

  6. Laser interrogation of surface agents (LISA) for chemical agent reconnaissance

    NASA Astrophysics Data System (ADS)

    Higdon, N. S.; Chyba, Thomas H.; Richter, Dale A.; Ponsardin, Patrick L.; Armstrong, Wayne T.; Lobb, C. T.; Kelly, Brian T.; Babnick, Robert D.; Sedlacek, Arthur J., III

    2002-06-01

    Laser Interrogation of Surface Agents (LISA) is a new technique which exploits Raman scattering to provide standoff detection and identification of surface-deposited chemical agents. ITT Industries, Advanced Engineering and Sciences Division is developing the LISA technology under a cost-sharing arrangement with the US Army Soldier and Biological Chemical Command for incorporation on the Army's future reconnaissance vehicles. A field-engineered prototype LISA-Recon system is being designed to demonstrate on-the- move measurements of chemical contaminants. In this article, we will describe the LISA technique, data form proof-of- concept measurements, the LISA-Recon design, and some of the future realizations envisioned for military sensing applications.

  7. Propulsion Options for the LISA Mission

    NASA Technical Reports Server (NTRS)

    Cardiff, Eric H.; Marr, Gregory C.

    2004-01-01

    The LISA mission is a constellation of three spacecraft operating at 1 AU from the Sun in a position trailing the Earth. After launch, a propulsion module provides the AV necessary to reach this operational orbit, and separates from the spacecraft. A second propulsion system integrated with the spacecraft maintains the operational orbit and reduces nongravitational disturbances on the instruments. Both chemical and electrical propulsion systems were considered for the propulsion module, and this trade is presented to show the possible benefits of an EP system. Several options for the orbit maintenance and disturbance reduction system are also briefly discussed, along with several important requirements that suggest the use of a FEEP thruster system.

  8. Nurse on the Move: Lisa Gorski.

    PubMed

    Gorski, Lisa; Gavin, Cara

    2016-01-01

    After a short hiatus, Nurses On the Move is back and better than ever! I am excited to bring you our next nurse leader, Lisa A. Gorski MS, RN, HHCNS-BC, CRNI, FAAN. With more than 30 years in the field, Gorski is an expert in both home healthcare and infusion nursing. As a clinical nurse specialist at Wheaton Franciscan Home Health & Hospice in Wisconsin, an editorial board member of Home Healthcare Now, an associate consultant for OASIS ANSWERS, Inc., and a published author, her knowledge of the nursing profession is truly impressive.Through our phone interview, I spoke with Gorski about why she decided to enter into home healthcare, her time as president of the Infusion Nurses Society, and what advice she has for a nurse starting their career.

  9. Why we use AT.Lisa multifocals?

    PubMed

    Filip, M; Nicolae, Miruna; Filip, A; Dragne, Carmen; Triantafyllidis, G; Antonescu, Cristina

    2014-01-01

    In this paper, the authors try to motivate their preference for implanting AT.Lisa Multifocals from all other premium IOL's from the market. It is emphasized, through clinical examples, that their choice comes after a long experience with this type of mul- tifocals IOL's. We make a short presentation of this particular type of MIOL's with their good but also weak points and try to motivate our decision to change from other types. We present the steps that each patient has to follow in our clinic prior to surgery itself, stressing out the idea that the discussion with the patient is very important in taking a decision regarding the implantation of a Premium IOL.

  10. eLISA and the Gravitational Universe

    NASA Astrophysics Data System (ADS)

    Danzmann, Karsten

    2015-08-01

    The last century has seen enormous progress in our understanding of the Universe. We know the life cycles of stars, the structure of galaxies, the remnants of the big bang, and have a general understanding of how the Universe evolved. We have come remarkably far using electromagnetic radiation as our tool for observing the Universe. However, gravity is the engine behind many of the processes in the Universe, and much of its action is dark. Opening a gravitational window on the Universe will let us go further than any alternative. Gravity has its own messenger: Gravitational waves, ripples in the fabric of spacetime. They travel essentially undisturbed and let us peer deep into the formation of the first seed black holes, exploring redshifts as large as z ~ 20, prior to the epoch of cosmic re-ionisation. Exquisite and unprecedented measurements of black hole masses and spins will make it possible to trace the history of black holes across all stages of galaxy evolution, and at the same time constrain any deviation from the Kerr metric of General Relativity. eLISA will be the first ever mission to study the entire Universe with gravitational waves. eLISA is an all-sky monitor and will offer a wide view of a dynamic cosmos using gravitational waves as new and unique messengers to unveil The Gravitational Universe. It provides the closest ever view of the early processes at TeV energies, has guaranteed sources in the form of verification binaries in the Milky Way, and can probe the entire Universe, from its smallest scales around singularities and black holes, all the way to cosmological dimensions.

  11. LISA Pathfinder Discharge Working Group: Activities, Results, and Lessons Learned for LISA/NGO

    NASA Astrophysics Data System (ADS)

    Ziegler, T.; Bergner, P.; Hechenblaikner, G.; Brandt, N.

    2013-01-01

    In 2011, the European Space Agency (ESA) entrusted Astrium GmbH to identify the root cause and corrective measures for the shortcomings of the LISA Pathfinder discharge system baseline that were identified during the system level testing in the torsion pendulum at the University of Trento. The main goal was to maximize the discharge system robustness under the given constraint to minimize the impact on manufacturing and the AIT process of the existing flight hardware. Astrium GmbH set-up a dedicated discharge working group (DWG) for 9 months, bringing together the expertise of surface scientists (DLR Stuttgart, Uni Würzburg, Uni Modena, BEAR Trieste) with the existing significant knowledge in the LTP community (Uni Trento, Imperial College London, CGS, Selex Galileo, TWT GmbH, ESA). The findings resulted in a recommendation to modify the baseline discharge system of LISA Pathfinder, including the definition of dedicated manufacturing and AIT requirements. These findings have relevance also for LISA/NGO, since they allow for a significantly more robust discharge system design.

  12. An Analysis of Coupling between the x1 and x12 Interferometers for LISA Pathfinder

    NASA Astrophysics Data System (ADS)

    Howard, Brittany

    2017-01-01

    Due to tolerances in the manufacturing process, noise from the jittering of the spacecraft housing LISA Pathfinder (LPF) is appearing in the differential measurement between its two test masses (TM's). This phenomenon manifests as a small but measurable coupling between the readouts of LPF's two heterodyne interferometers, x1 and x12. In this study, two LISA Pathfinder experiments are analyzed using three methods in an effort to characterize and quantify the coupling as well as to potentially identify its source. The main question considered is this: does the coupling change with the absolute displacement between the TM's? As a result of this work, reliable values for coupling between LPF's x1 and x12 interferometers are found, and they are seen to depend on the absolute displacement between the test masses to some degree. Completed at the Albert Einstein Institute for Gravitational Physics under the International REU program from the University of Florida.

  13. LISA Experience from GRACE-FO Optical Payload (LEGOP)

    NASA Astrophysics Data System (ADS)

    McKenzie, Kirk

    We propose to develop in-flight tests of high-risk elements of laser interferometry for gravitational wave astronomy missions, such as the Laser Interferometer Space Antenna (LISA) mission, for deployment on the GRACE-FO mission. The proposed set of experiments, LISA Experience from GRACE-FO Optical Payload (LEGOP), exploits the similarities between the LISA and GRACE-FO optical links to use GRACE-FO as a "mission of opportunity" for demonstration of high-risk and innovative technologies for the LISA mission. We will develop FPGA algorithms for the tests and perform laboratory experiments and hardware-in-the-loop simulations to verify them. Specifically, we will target the following aspects of LISA inter-spacecraft interferometry: 1. Absolute optical-ranging and Time Delay Interferometry (TDI). TDI is the process used on LISA to combine one-way inter-spacecraft measurements to form synthesized interferometers, such as the Michelson interferometer, that are free of laser frequency noise, but retain the gravitational wave signal. The one-way measurements must be combined with precise delays, proportional to the light travel time between spacecraft (the range) and difference of on board clocks. The proposed in-flight experiment would see a LISA like optical ranging system deployed to provide the required delays for a TDI experiment on GRACE-FO. We will develop the FPGA code required for this experiment and perform validation of this optical-ranging system for GRACE-FO through a TDI experiment on the JPL LISA interferometer testbed. 2. Arm-locking: A technique for transferring the stability of the spacecraft separation to the laser frequency. Because arm-locking uses the LISA arms, the best frequency reference available, it offers unparalleled stability and requires no additional flight hardware. It cannot be demonstrated experimentally in a LISA-like environment on Earth. An in-flight demonstration of arm-locking would validate the operation of arm- locking, enabling

  14. Simulations of laser locking to a LISA arm

    SciTech Connect

    Sylvestre, Julien

    2004-11-15

    We present detailed numerical simulations of a laser phase stabilization scheme for Laser Interferometer Space Antenna (LISA), where both lasers emitting along one arm are locked to each other. Including the standard secondary noises and spacecraft motions that approximately mimic LISA's orbit (excluding the rotation of the constellation), we verify that very stable laser phases can be obtained and that time delay interferometry can be used to remove the laser phase noise from measurements of gravitational wave strains. Most importantly, we show that this locking scheme can provide significant simplifications over LISA's baseline design in the implementation of time delay interferometry.

  15. Observing Massive Black Hole Binary Coalescences with LISA

    NASA Technical Reports Server (NTRS)

    Centrella, Joan

    2005-01-01

    Massive black hole binary coalescences are among the most important astrophysical sources of gravitational waves to be observed by LISA. The ability to observe and characterize such sources with masses approximately equal to 105 M/odot and larger at high redshifts is strongly dependent on the sensitivity of LISA in the low frequency (0.1 mHz and below) regime. We examine LISA's ability to observe these systems at redshifts up to z approximately equal to 10 for various proposed values of the low frequency sensitivity, under current assumptions about the merger rates. The discussion will focus on the astrophysical information that can be gained by these observations.

  16. Laying the Foundation for Space-based Gravitational Wave Detection: LISA Pathfinder, the LISA Test Package, and ST7-DRS

    NASA Astrophysics Data System (ADS)

    Thorpe, James

    2014-08-01

    Efforts to develop space-based observatories of gravitational waves, such as the long-standing Laser Interferometer Space Antenna (LISA) or the more recent eLISA concept that motivated ESA’s selection of a gravitational wave mission for the L3 Mission Opportunity, have traditionally been praised for their scientific potential and criticized for their technological readiness. The LISA Pathfinder (LPF) mission is a dedicated technology demonstrator for such missions. Led by ESA and a consortium of European national agencies and with a minority contribution from NASA, LPF will demonstrate several key technologies for the LISA concept. LPF includes two scientific payloads: the European LISA Technology Package (LTP) and the NASA-provided ST7-DRS. The mission will place two test masses in drag-free flight and measure the relative acceleration between them. This measurement will validate a number of technologies that are critical to LISA-like gravitational wave instruments including sensing and control of the test masses, drag-free control laws, micro-Newton thrusters, and picometer-level laser metrology. LPF is currently in the late stages of integration and test and is planned to launch in 2015. We will present the current status of the LISA Pathfinder mission and the LTP and ST7-DRS payloads as well as the expected impact on the larger gravitational-wave effort.

  17. LISA Pathfinder paves way for gravitational-wave probe

    NASA Astrophysics Data System (ADS)

    Johnston, Hamish

    2016-07-01

    Researchers working on the LISA Pathfinder space mission have successfully managed to isolate from the environment two 2 kg test masses at a special “Lagrangian point” between the Earth and the Sun.

  18. Time Domain Simulations of Arm Locking in LISA

    NASA Technical Reports Server (NTRS)

    Thorpe, J. I.; Maghami, P.; Livas, Jeff

    2011-01-01

    Arm locking is a technique that has been proposed for reducing laser frequency fluctuations in the Laser Interferometer Space Antenna (LISA). a gravitational-wave observatory sensitive' in the milliHertz frequency band. Arm locking takes advantage of the geometric stability of the triangular constellation of three spacecraft that comprise LISA to provide a frequency reference with a stability in the LISA measurement band that exceeds that available from a standard reference such as an optical cavity or molecular absorption line. We have implemented a time-domain simulation of arm locking including the expected limiting noise sources (shot noise, clock noise. spacecraft jitter noise. and residual laser frequency noise). The effect of imperfect a priori knowledge of the LISA heterodyne frequencies and associated "pulling" of an arm locked laser is included. We find that our implementation meets requirements both on the noise and dynamic range of the laser frequency.

  19. PREFACE: XTOP 2004 -- 7th Biennial Conference on High Resolution X-Ray Diffraction and Imaging

    NASA Astrophysics Data System (ADS)

    Holý, Vaclav

    2005-05-01

    The 7th Biennial Conference on High Resolution X-Ray Diffraction and Imaging (XTOP 2004) was held in the Prague suburb of Pruhonice, Czech Republic, during 7-10 September 2004. It was organized by the Czech and Slovak Crystallographic Association in cooperation with the Institute of Physics, Academy of Sciences of the Czech Republic, Prague, Masaryk University, Brno, and Charles University, Prague. XTOP 2004 took place just after EPDIC IX (European Powder Diffraction Conference) organised in Prague by the same Association during 2-5 September 2004. The Organizing Committee was supported by an International Programme Committee including about 20 prominent scientists from several European and overseas countries, whose helpful suggestions for speakers are acknowledged. The conference was sponsored by the International Union of Crystallography and by several industrial sponsors; this sponsorship allowed us to support about 20 students and young scientists. In total, 147 official delegates and 8 accompanying persons from 16 countries of three continents attended our conference. The scientific programme of the conference was divided into 11 half-day sessions and 2 poster sessions. The participants presented 147 accepted contributions; of these 9 were 45-minute long invited talks, 34 were 20-minute oral presentations and 104 were posters. All posters were displayed for the whole meeting to ensure maximum exposure and interaction between delegates. We followed the very good experience from the previous conference, XTOP 2002, and also organized pre-conference tutorial lectures presented by experts in the field: `Imaging with hard synchrotron radiation' (J Härtwig, Grenoble), `High-resolution x-ray diffractometry: determination of strain and composition' (J Stangl, Linz), `X-ray grazing-incidence scattering from surfaces and nanostructures' (U Pietsch, Potsdam) and `Hard x-ray optics' (J Hrdý, Prague). According to the recommendation of the International Program Committee

  20. Morphometric variations of the 7th cervical vertebrae of Zulu, White, and Colored South Africans.

    PubMed

    Kibii, Job M; Pan, Rualing; Tobias, Phillip V

    2010-05-01

    The 7th cervical vertebrae of 240 cadavers of South African Zulu, White, and Colored population groups were examined to determine morphometric variation. White and Colored females had statistically significant narrower cervical anteroposterior diameters than their male counterparts, whereas no statistically significant difference between sexes of the Zulu population group was observed in this variable. In addition, although Zulu and Colored females had statistically significant narrower cervical transverse diameters than their male counterparts, there was no statistically significant variation between South African white males and females in this respect. The findings indicate that sexual dimorphism is more apparent in the vertebral centrum, across the three population groups, where males had significantly larger dimensions in centrum anteroposterior diameter, height, and width than their female counterparts. The study further reveals that sexual dimorphism is more apparent when one compares aspects of the 7th cervical vertebra between sexes within the same population group. Overall, the dimensions of the various variates of the vertebra are substantially smaller in women than in men. The smaller dimensions, particularly of the centrum, may be the result of lower skeletal mass in women and render them more vulnerable to fractures resulting from compression forces.

  1. Aspects That Concern Assessing Lower Secondary School Students at the Physics National Contest Exemplification for the 7th Grade

    ERIC Educational Resources Information Center

    Florian, Gabriel

    2014-01-01

    In the present article, we aim at analysing the results obtained by the 7th grade students who participated in the 50th edition of the Physics National Contest, which took place in Cluj-Napoca between the 6th and the 11th of April, 2014. Why have we chosen the 7th grade? One of the reasons is represented by the good results obtained by the…

  2. LISA Pathfinder as a micrometeorite instrument

    NASA Astrophysics Data System (ADS)

    Thorpe, James

    2016-03-01

    The Solar System contains a population of dust and small particles originating from asteroids, comets, and other bodies. These particles have been studied using a number of techniques ranging from in-situ satellite detectors to analysis of lunar microcraters to ground-based observations of zodiacal light. We describe an approach for using the LISA Pathfinder [LPF] mission as an instrument to detect and characterize the dynamics of dust particles in the vicinity of Earth-Sun L1. Launched on Dec. 3rd, 2015, LPF is a dedicated technology demonstrator mission that will validate several key technologies for a future space-based gravitational-wave observatory. The primary science instrument aboard LPF is a precision accelerometer which we show will be capable of sensing discrete momentum impulses as small as 4 × 10-8 N . s. We then estimate the rate of such impulses resulting from impacts of micrometeoroids based on standard models of the micrometeoroid environment in the inner solar system. We find that LPF may detect dozens to hundreds of individual events corresponding to impacts of particles with masses > 10-9 g during LPF's roughly six-month science operations phase.

  3. LISA and its in-flight test precursor SMART-2

    NASA Astrophysics Data System (ADS)

    Vitale, S.; Bender, P.; Brillet, A.; Buchman, S.; Cavalleri, A.; Cerdonio, M.; Cruise, M.; Cutler, C.; Danzmann, K.; Dolesi, R.; Folkner, W.; Gianolio, A.; Jafry, Y.; Hasinger, G.; Heinzel, G.; Hogan, C.; Hueller, M.; Hough, J.; Phinney, S.; Prince, T.; Richstone, D.; Robertson, D.; Rodrigues, M.; Rüdiger, A.; Sandford, M.; Schilling, R.; Shoemaker, D.; Schutz, B.; Stebbins, R.; Stubbs, C.; Sumner, T.; Thorne, K.; Tinto, M.; Touboul, P.; Ward, H.; Weber, W.; Winkler, W.

    2002-07-01

    LISA will be the first space-home gravitational wave observatory. It aims to detect gravitational waves in the 0.1 mHz÷1 Hz range from sources including galactic binaries, super-massive black-hole binaries, capture of objects by super-massive black-holes and stochastic background. LISA is an ESA approved Cornerstone Mission foreseen as a joint ESA-NASA endeavour to be launched in 2010-11. The principle of operation of LISA is based on laser ranging of test-masses under pure geodesic motion. Achieving pure geodesic motion at the level requested for LISA, 3×10 -15 ms -2/√Hz at 0.1 mHz, is considered a challenging technological objective. To reduce the risk, both ESA and NASA are pursuing an in-flight test of the relevant technology. The goal of the test is to demonstrate geodetic motion within one order of magnitude from the LISA performance. ESA has given this test as the primary goal of its technology dedicated mission SMART-2 with a launch in 2006. This paper describes the basics of LISA, its key technologies, and its in-flight precursor test on SMART-2.

  4. Charge It! Translating Electric Vehicle Research Results to Engage 7th and 8th Grade Girls

    NASA Astrophysics Data System (ADS)

    Egbue, Ona; Long, Suzanna; Ng, Ean-Harn

    2015-10-01

    Despite attempts to generate interest in science and technology careers, US students continue to show reduced interest in science, technology, engineering and mathematics (STEM) majors at the collegiate level. If girls are not engaged in STEM learning by the middle school level, studies show that they are even less likely to choose a science- or engineering-related major. This article presents results from a workshop for 7th and 8th grade girls designed to promote knowledge building in the area of sustainability and alternative energy use in transportation and to stimulate greater interest in STEM subjects. The workshop based on research conducted at University X focused on basic concepts of electric vehicles and electric vehicles' batteries. Tests were conducted to evaluate the students' knowledge and perceptions of electric vehicles and to determine the impact of the workshop. Early exposure to meaningful engineering experiences for these young girls may boost interest and the eventual pursuit of engineering and technology education paths.

  5. [Dilemmas of the pharmacist, 7th edition of Hungarian National Formulary in practice].

    PubMed

    Pál, Szilárd

    2005-01-01

    Most important event of year 2004 of the history of Hungarian pharmacy was the release of the 7th edition of the National Formulary. The general part of the new formulary expanded, remarks on the preparations are more detailed and dispensing technologies are more elaborated. Knowledge base on pharmaceutical substances and incompatibility is inserted as novelty. Following the principles of modern pharmacy practice the new National Formulary excludes pills, though it is still accepted as an alternative dosage form. Usage of tablets, hard gelatine capsules and medication stick as a new dosage forms are introduced. The aim of my study was to prepare and examine some new compositions of the new edition of the National Formulary to help the pharmacist's work. Results confirmed the novel solutions of the new National Formulary.

  6. Student Solutions Manual to accompany Fundamentals of Physics,7th Edition

    NASA Astrophysics Data System (ADS)

    Halliday, David; Resnick, Robert; Walker, Jearl; Christman, J. Richard

    2004-06-01

    Work more effectively and check solutions as you go along with the text! This Student Solutions Manual that accompanies Fundamentals of Physics, 7th Edition, provides readers with complete, worked-out solutions to 30% of the end-of-chapter problems. These problems are indicated in the text by an ssm icon. No other book on the market today can match the 30-year success of Halliday, Resnick and Walker's Fundamentals of Physics! In a breezy, easy-to-understand style this Seventh Edition offers a solid understanding of fundamental physics concepts, and helps readers apply this conceptual understanding to quantitative problem solving. This book offers a unique combination of authoritative content and stimulating applications.

  7. PREFACE: Proceedings of the 7th Liquid Matter Conference (Lund, Sweden, 27 June 1 July 2008)

    NASA Astrophysics Data System (ADS)

    Kahl, Gerhard; Sciortino, Francesco; Ullner, Magnus

    2008-12-01

    (Utrecht) and to Professor Peter Pusey (Edinburgh) for their seminal studies of colloidal matter. In addition to plenary speeches by the two recipients of the Liquid Matter Prize, the scientific program consisted of ten plenary lectures, 108 symposia talks, 23 of which were keynote lectures, and 458 poster contributions. This special issue of Journal of Physics: Condensed Matter contains 47 of the oral communications. The conference was held in the buildings of Lund University and the Student Union facing the University Square in the heart of Lund. The organizers gratefully acknowledge the substantial financial support offered by the Nobel Foundation and by the Swedish Research Council. The success of the conference owes a great debt of gratitude to the members of the Local Organizing Committee and all the people who helped them tirelessly (and very efficiently) to make the conference run smoothly and to the members of the International Program Committee, who were deeply involved in the planning of the conference. During the conference dinner our colleague Lennart Piculell gave a singing performance, which included a song dedicated to the two winners of the Liquid Matter Prize, entitled Hard-Breaking Gel, whose lyrics are printed below. Finally, the Board of the Liquids Section of the European Physical Society decided that the 8th Liquid Matter Conference will be held in Vienna (Austria) 6-10 September 2011. Hard-Breaking Gel New lyrics by Lennart Piculell to the melody of Heartbreak Hotel, created in June 2008 for the 7th Liquid Matter Conference, dedicated to Henk Lekkerkerker and Peter Pusey. Well, since my baby left me, I found a new place to be! It's downtown Lund, in a narrow street, Where hundreds of cool people meet! There I don't feel lonely, No, I don't feel lonely - So, if you feel lonely, you should try! It's all about liquid matter: Liquids flow, and soft bodies swell! Your mind is blown, and your blood will boil To a hard-breaking gel. And you won't be lonely

  8. Technology development for the LISA using the UF Torsion Pendulu

    NASA Astrophysics Data System (ADS)

    Conklin, John W.; Chilton, Andrew; Olatunde, Taiwo; Apple, Stephen; Ciani, Giacomo; Mueller, Guido

    2015-08-01

    Space-based gravitational wave observatories like LISA measure picometer changes in the distances between free falling test masses separated by millions of kilometers caused by gravitational waves. A test mass and its associated sensing, actuation, charge control and caging subsystems are referred to as a gravitational reference sensor (GRS). LISA will observe gravitational wave sources ranging from super-massive black hole mergers to compact galactic binaries in the millihertz region, and LISA science has consistently been ranked in the top two for future large space missions in the last two NASA astrophysics decadal reviews. With the 2015 launch of LISA Pathfinder (LPF) and the expected detection of gravitational waves by aLIGO and/or Pulsar Timing Arrays within in the next several years, this can arguably be called the decade of gravitational waves. Following a successful demonstration of the baseline LISA GRS by LPF, the measurement principle will be carried forward, but improvements in several GRS components are possible over the next ten years that will lead to cost savings and potential noise reductions. The UF LISA group has constructed the UF Torsion Pendulum to increase U.S. competency in this critical area and to have a facility where new technologies can be developed and evaluated. This experimental facility is based on the design of a similar facility at the University of Trento, and consists of a vacuum enclosed torsion pendulum that suspends mock-ups of the LISA test masses, surrounded by electrode housings. This presentation will describe this facility, focusing on its mechanical design, capacitive sensing and electrostatic actuation systems, and overall acceleration noise performance

  9. Nano-LISA for in vitro diagnostic applications

    NASA Astrophysics Data System (ADS)

    Maswadi, Saher; Glickman, Randolph D.; Elliott, Rowe; Barsalou, Norman

    2011-03-01

    We previously reported the detection of bacterial antigen with immunoaffinity reactions using laser optoacoustic spectroscopy and antibody-coupled gold nanorods (Ab-NR) as a contrast agent specifically targeted to the antigen of interest. The Nano-LISA (Nanoparticle Linked Immunosorbent Assay) method has been adapted to detect three very common blood-borne viral infectious agents, i.e. human T-lymphotropic virus (HTLV), human immunodeficiency virus (HIV) and hepatitis-B (Hep-B). These agents were used in a model test panel to illustrate the performance of the Nano-LISA technique. A working laboratory prototype of a Nano-LISA microplate reader-sensor was assembled and tested against the panel containing specific antigens of each of the infectious viral agents. Optoacoustic (OA) responses generated by the samples were detected using the probe beam deflection technique, an all-optical, non-contact technique. A LabView graphical user interface was developed for control of the instrument and real-time display of the test results. The detection limit of Nano-LISA is at least 1 ng/ml of viral antigen, and can reach 10 pg/ml, depending on the binding affinity of the specific detection antibody used to synthesize the Ab-NR. The method has sufficient specificity, i.e. the detection reagents do not cross-react with noncomplementary antigens. Thus, the OA microplate reader, incorporating NanoLISA, has adequate detection sensitivity and specificity for use in clinical in vitro diagnostic testing.

  10. Revisiting the LISA science case in a changing astrophysical landscape

    NASA Astrophysics Data System (ADS)

    Cornish, Neil

    2016-03-01

    While the basic LISA concept has changed little over the past 20 years, advances in astrophysics and cosmology over this time have been dramatic. Future missions such as JWST, Euclid, WFIRST and Athena will further reshape the landscape prior to the LISA launch in the 2030s, as may discoveries by gravitational wave detectors operating in other frequency bands. These developments require us to periodically revist the LISA science case, and identify new synergies with other observatories. For example, Euclid and WFIRST are expected to detect dozens of very high redshift (z > 8) AGN, revealing the high mass tail of the early black hole population, while a suitably configured LISA mission could provide complimentary information about lower mass systems at these redshifts. Closer to home, recent surveys indicate that there are far fewer compact binary sources than originally estimated, which may be the one time where having fewer gravitational wave sources is a good thing as the foreground ``noise'' is reduced, while the number of resolved galactic sources is essentially unchanged. I will discuss these, and many other changes to the LISA science landscape, and consider how they might impact the science case and the mission design.

  11. Mona Lisa is always happy - and only sometimes sad.

    PubMed

    Liaci, Emanuela; Fischer, Andreas; Heinrichs, Markus; van Elst, Ludger Tebartz; Kornmeier, Jürgen

    2017-03-10

    The worldwide fascination of da Vinci's Mona Lisa has been dedicated to the emotional ambiguity of her face expression. In the present study we manipulated Mona Lisa's mouth curvature as one potential source of ambiguity and studied how a range of happier and sadder face variants influences perception. In two experimental conditions we presented different stimulus ranges with different step sizes between stimuli along the happy-sad axis of emotional face expressions. Stimuli were presented in random order and participants indicated the perceived emotional face expression (first task) and the confidence of their response (second task). The probability of responding 'happy' to the original Mona Lisa was close to 100%. Furthermore, in both conditions the perceived happiness of Mona Lisa variants described sigmoidal functions of the mouth curvature. Participants' confidence was weakest around the sigmoidal inflection points. Remarkably, the sigmoidal functions, as well as confidence values and reaction times, differed significantly between experimental conditions. Finally, participants responded generally faster to happy than to sad faces. Overall, the original Mona Lisa seems to be less ambiguous than expected. However, perception of and reaction to the emotional face content is relative and strongly depends on the used stimulus range.

  12. Distinguishing Between Formation Channels for Binary Black Holes with LISA

    NASA Astrophysics Data System (ADS)

    Breivik, Katelyn; Rodriguez, Carl L.; Larson, Shane L.; Kalogera, Vassiliki; Rasio, Frederic A.

    2017-01-01

    The recent detections of GW150914 and GW151226 imply an abundance of stellar-mass binary-black-hole mergers in the local universe. While ground-based gravitational-wave detectors are limited to observing the final moments before a binary merges, space-based detectors, such as the Laser Interferometer Space Antenna (LISA), can observe binaries at lower orbital frequencies where such systems may still encode information about their formation histories. In particular, the orbital eccentricity and mass of binary black holes in the LISA frequency band can be used together to discriminate between binaries formed in isolation in galactic fields and those formed in dense stellar environments such as globular clusters. In this letter, we explore the orbital eccentricity and mass of binary-black-hole populations as they evolve through the LISA frequency band. Overall we find that there are two distinct populations discernible by LISA. We show that up to ~90% of binaries formed either dynamically or in isolation have eccentricities measurable by LISA. Finally, we note how measured eccentricities of low-mass binary black holes evolved in isolation could provide detailed constraints on the physics of black-hole natal kicks and common-envelope evolution.

  13. LISA: Science and Prospects for Gravitational Wave Detection in Space

    NASA Astrophysics Data System (ADS)

    Larson, Shane L.

    2017-01-01

    Spaceborne gravitational wave observatories with million kilometer armlengths will probe gravitational waves with kilosecond periods. This part of the spectrum is populated by a diverse menagerie of high energy astrophysical systems that will give new insights into stellar evolution, the formation and evolution of super-massive black holes, and the growth of structure in the Universe. LISA is a laser interferometric observatory that will be sensitive to gravitational wave frequencies from about 10 microHertz to about 1 Hertz, providing gravitational wave observations of these phenomena that will enable population studies, detailed characterization of the structure and bulk motion of matter in these systems, as well as enabling new, detailed tests of physics in strong gravitational fields. The core LISA measurement has been demonstrated by the successful flight of LISA Pathfinder, paving the way for the start of LISA mission design and planning. In this talk, we will discuss the science that low-frequency gravitational wave observations will reveal and enable, as well as the current technology status and progress forward toward an eventual LISA flight.

  14. Distinguishing between Formation Channels for Binary Black Holes with LISA

    NASA Astrophysics Data System (ADS)

    Breivik, Katelyn; Rodriguez, Carl L.; Larson, Shane L.; Kalogera, Vassiliki; Rasio, Frederic A.

    2016-10-01

    The recent detections of GW150914 and GW151226 imply an abundance of stellar-mass binary black hole (BBH) mergers in the local universe. While ground-based gravitational wave detectors are limited to observing the final moments before a binary merges, space-based detectors, such as the Laser Interferometer Space Antenna (LISA), can observe binaries at lower orbital frequencies where such systems may still encode information about their formation histories. In particular, the orbital eccentricity and mass of BBHs in the LISA frequency band can be used together to discriminate between binaries formed in isolation in galactic fields and those formed in dense stellar environments such as globular clusters. In this letter, we explore the orbital eccentricity and mass of BBH populations as they evolve through the LISA frequency band. Overall we find that there are two distinct populations discernible by LISA. We show that up to ∼ 90 % of binaries formed either dynamically or in isolation have eccentricities that are measurable with LISA. Finally, we note how measured eccentricities of low-mass BBHs evolved in isolation could provide detailed constraints on the physics of black hole natal kicks and common-envelope evolution.

  15. LISA technology development using the UF precision torsion pendulum

    NASA Astrophysics Data System (ADS)

    Apple, Stephen; Chilton, Andrew; Olatunde, Taiwo; Ciani, Giacomo; Mueller, Guido; Conklin, John

    2015-04-01

    LISA will directly observe low-frequency gravitational waves emitted by sources ranging from super-massive black hole mergers to compact galactic binaries. A laser interferometer will measure picometer changes in the distances between free falling test masses separated by millions of kilometers. A test mass and its associated sensing, actuation, charge control and caging subsystems are referred to as a gravitational reference sensor (GRS). The demanding acceleration noise requirement for the LISA GRS has motivated a rigorous testing campaign in Europe and a dedicated technology mission, LISA Pathfinder, scheduled for launch in the fall of 2015. At the University of Florida we are developing a nearly thermally noise limited torsion pendulum for testing GRS technology enhancements that may improve the performance and/or reduce the cost of the LISA GRS. This experimental facility is based on the design of a similar facility at the University of Trento, and consists of a vacuum enclosed torsion pendulum that suspends mock-ups of the LISA test masses, surrounded by electrode housings. Some of the technologies that will be demonstrated by this facility include a novel TM charge control scheme based on ultraviolet LEDs, an all-optical TM position and attitude sensor, and drift mode operation. This presentation will describe the design of the torsion pendulum facility, its current acceleration noise performance, and the status of the GRS technologies under development.

  16. Transforming Science and Technology: Our Future Depends on It. Volume 1 [and] Volume 2: Proceedings and Contributions to the International Gender and Science and Technology Conference (7th, Waterloo, Ontario, Canada, July 31-August 5, 1993) = Transformer les sciences et la technologie: notre avenir en depend. Volume 1 [and] Volume 2. Les soumissions a la septieme conference internationale sur l'equite des sexes en science et en technologie (du 31 juillet au 5 aout 1993).

    ERIC Educational Resources Information Center

    Haggerty, Sharon, Ed.; Holmes, Ann, Ed.

    This two-volume set of papers was produced for the seventh International Gender and Science and Technology (GASTA) Conference. Abstracts of all papers and other presentations have been translated and are published in both English and French. Papers are published in the language in which they were submitted (English or French). GASAT provides a…

  17. PREFACE: EUCAS '05: The 7th European Conference on Applied Superconductivity (Vienna University of Technology, Austria, 11 15 September 2005)

    NASA Astrophysics Data System (ADS)

    Donaldson, Gordon; Weber, Harald W.; Sauerzopf, Franz M.

    2006-03-01

    This issue of Superconductor Science and Technology contains the plenary and invited papers presented at the 7th European Conference on Applied Superconductivity (EUCAS '05) that was held at the Vienna University of Technology from 11-15 September 2005. All those contributed papers that were submitted to the Conference Proceedings will be published in the Journal of Physics: Conference Series. The scientific aims of EUCAS '05 followed the tradition established at the preceding conferences in Göttingen, Edinburgh, Eindhoven, Sitges (Barcelona), Lyngby (Copenhagen) and finally Sorrento (Napoli). The focus was placed on the interplay between the most recent developments in superconductor research and the positioning of applications of superconductivity in the marketplace. Although initially founded as an exchange forum mainly for European scientists, it has gradually developed into a truly international meeting with significant attendance from the Far East and the United States. The Vienna conference attracted 813 participants in the scientific programme and 90 accompanying persons. 59% of all participants came from Europe, 31% from the Far East, 6% from the United States and Canada as well as 4% from other nations worldwide. 27 companies presented their latest developments in the field. 32 plenary and invited lectures highlighted the state-of-the-art in the areas of materials, large-scale as well as small-scale applications; 625 contributed papers (among them 556 posters) demonstrated the broad range of exciting activities in all research areas of our field. EUCAS '05 spread a lot of optimism and enthusiasm for this fascinating field of research and for its well established technological potential, especially among the numerous young researchers attending this conference. We are grateful to all those who participated in the meeting and contributed to its success.

  18. Effects of the 5th and 7th grade enhanced versions of the keepin' it REAL substance use prevention curriculum.

    PubMed

    Elek, Elvira; Wagstaff, David A; Hecht, Michael L

    2010-01-01

    This study assessed the outcomes of adapting the culturally-grounded, middle school, substance-use prevention intervention, keepin ' it REAL (kiR), to target elementary school students and to address acculturation. At the beginning of 5th grade, 29 schools were randomly assigned to conditions obtained by crossing grade of implementation (5th, 7th, 5th + 7th, and control/comparison) by curriculum version [kiR-Plus vs. kiR-Acculturation Enhanced (AE)]. Students (n = 1984) completed 6 assessments through the end of 8th grade. The kiR curricula generally appear no more effective than the comparison schools' programming. Students receiving either version of the kiR intervention in only the 5th grade report greater increases in substance use than did control students. Receiving the kiR-AE version twice (both 5th and 7th grades) has benefits over receiving it once.

  19. Black-hole Merger Simulations for LISA Science

    NASA Technical Reports Server (NTRS)

    Kelly, Bernard J.; Baker, John G.; vanMeter, James R.; Boggs, William D.; Centrella, Joan M.; McWilliams, Sean T.

    2009-01-01

    The strongest expected sources of gravitational waves in the LISA band are the mergers of massive black holes. LISA may observe these systems to high redshift, z>10, to uncover details of the origin of massive black holes, and of the relationship between black holes and their host structures, and structure formation itself. These signals arise from the final stage in the development of a massive black-hole binary emitting strong gravitational radiation that accelerates the system's inspiral toward merger. The strongest part of the signal, at the point of merger, carries much information about the system and provides a probe of extreme gravitational physics. Theoretical predictions for these merger signals rely on supercomputer simulations to solve Einstein's equations. We discuss recent numerical results and their impact on LISA science expectations.

  20. Development of Fiber-Based Laser Systems for LISA

    NASA Technical Reports Server (NTRS)

    Numata, Kenji; Camp, Jordan

    2010-01-01

    We present efforts on fiber-based laser systems for the LISA mission at the NASA Goddard Space Flight Center. A fiber-based system has the advantage of higher robustness against external disturbances and easier implementation of redundancies. For a master oscillator, we are developing a ring fiber laser and evaluating two commercial products, a DBR linear fiber laser and a planar-waveguide external cavity diode laser. They all have comparable performance to a traditional NPRO at LISA band. We are also performing reliability tests of a 2-W Yb fiber amplifier and radiation tests of fiber laser/amplifier components. We describe our progress to date and discuss the path to a working LISA laser system design.

  1. Working Towards the LISA Optical Benches at UF

    NASA Astrophysics Data System (ADS)

    Chilton, Andrew; Hillsberry, Daniel; Ciani, Giacomo; Conklin, John; Mueller, Guido

    2017-01-01

    The first space-based gravitational wave observatory will likely be a six-link LISA-like observatory with three million km scale arms. LISA aims at detecting gravitational waves from super-massive black hole mergers, compact galactic binaries, and many other exciting sources which emit gravitational waves in the 10 µHz to 1Hz frequency band. LISA will use laser interferometry to measure changes in the distance between free floating test masses at the pm/Hz level. At the core of the interferometry are the optical benches (two on each spacecraft) which receive, manipulate and redirect the different laser beams. The optical bench has been identified as a critical item in the design, manufacturing, and testing phases of this mission. Our group studies different components of the optical bench with the goal to simplify the design and manufacturing process of the optical bench.

  2. Exploring Parameter Space Coverage of Various LISA Configurations

    NASA Astrophysics Data System (ADS)

    Katz, Michael L.

    2017-01-01

    With the success of LISA Pathfinder, the measurement of gravitational waves in space has taken an important step forward. We conduct an analysis of the measurement abilities of distinctive LISA detector designs, examining how the low-frequency band-edge behavior of the detector sensitivity curve affects measurement capabilities. We are particularly interested in LISA’s ability to measure massive black holes that are merging near the band-edge, with masses in the range of $\\sim 10^6-10^{10}M_\\odot$. We examine the ringdown and insprial detectability over a wide range of Massive Black Hole (MBH) binaries along with a broad palette of possible LISA design parameters.

  3. LISA Pathfinder: picometers and femtoNewtons in space

    NASA Astrophysics Data System (ADS)

    Hewitson, Martin; LISA Pathfinder Team Team

    2016-03-01

    On December 3rd at 04:04 UTC, The European Space Agency launched the LISA Pathfinder satellite on board a VEGA rocket from Kourou in French Guiana. After a series of orbit raising manoeuvres and a 2 month long transfer orbit, LISA Pathfinder arrived at L1. Following a period of commissioning, the science operations commenced at the start of March, beginning the demonstration of technologies and methodologies which pave the way for a future large-scale gravitational wave observatory in space. This talk will present the scientific goals of the mission, discuss the technologies being tested, elucidate the link to a future space-based observatory, such as LISA, and present preliminary results from the in-orbit operations and experiments.

  4. Bayesian statistics for the calibration of the LISA Pathfinder experiment

    NASA Astrophysics Data System (ADS)

    Armano, M.; Audley, H.; Auger, G.; Binetruy, P.; Born, M.; Bortoluzzi, D.; Brandt, N.; Bursi, A.; Caleno, M.; Cavalleri, A.; Cesarini, A.; Cruise, M.; Danzmann, K.; Diepholz, I.; Dolesi, R.; Dunbar, N.; Ferraioli, L.; Ferroni, V.; Fitzsimons, E.; Freschi, M.; García Marirrodriga, C.; Gerndt, R.; Gesa, L.; Gibert, F.; Giardini, D.; Giusteri, R.; Grimani, C.; Harrison, I.; Heinzel, G.; Hewitson, M.; Hollington, D.; Hueller, M.; Huesler, J.; Inchauspé, H.; Jennrich, O.; Jetzer, P.; Johlander, B.; Karnesis, N.; Kaune, B.; Korsakova, N.; Killow, C.; Lloro, I.; Maarschalkerweerd, R.; Madden, S.; Mance, D.; Martin, V.; Martin-Porqueras, F.; Mateos, I.; McNamara, P.; Mendes, J.; Mitchell, E.; Moroni, A.; Nofrarias, M.; Paczkowski, S.; Perreur-Lloyd, M.; Pivato, P.; Plagnol, E.; Prat, P.; Ragnit, U.; Ramos-Castro, J.; Reiche, J.; Romera Perez, J. A.; Robertson, D.; Rozemeijer, H.; Russano, G.; Sarra, P.; Schleicher, A.; Slutsky, J.; Sopuerta, C. F.; Sumner, T.; Texier, D.; Thorpe, J.; Trenkel, C.; Tu, H. B.; Vitale, S.; Wanner, G.; Ward, H.; Waschke, S.; Wass, P.; Wealthy, D.; Wen, S.; Weber, W.; Wittchen, A.; Zanoni, C.; Ziegler, T.; Zweifel, P.

    2015-05-01

    The main goal of LISA Pathfinder (LPF) mission is to estimate the acceleration noise models of the overall LISA Technology Package (LTP) experiment on-board. This will be of crucial importance for the future space-based Gravitational-Wave (GW) detectors, like eLISA. Here, we present the Bayesian analysis framework to process the planned system identification experiments designed for that purpose. In particular, we focus on the analysis strategies to predict the accuracy of the parameters that describe the system in all degrees of freedom. The data sets were generated during the latest operational simulations organised by the data analysis team and this work is part of the LTPDA Matlab toolbox.

  5. Abstracts presented at the 7th World Alliance for Risk Factor Surveillance (WARFS) Global Conference. October 16-19, 2011. Toronto, Ontario, Canada.

    PubMed

    2012-01-01

    The 7th World Alliance for Risk Factor Surveillance (WARFS) Global Conference, hosted by the Public Health Agency of Canada, was held in Toronto, Ontario, Canada, from October 16 to 19, 2011. Previous WARFS conferences were held in USA (1999), Finland (2001), Australia (2003), Uruguay (2005) and Italy (2007, 2009). WARFS is a global working group on surveillance under the International Union for Health Promotion and Education (IUHPE) It supports the development of risk factor surveillance as a tool for evidence-based public health, acknowledging the importance of this source of information to inform, monitor and evaluate disease prevention and health promotion policies and programs. The theme of the 2011 Global Conference was the role of surveillance in the promotion of health. The Global Conference had 146 registered participants, making it the second most attended WARFS conference in its history. Over the three days, participants attended oral and poster presentations from 30 countries. The conference would not have been possible without the hard work of the International Scientific Committee and the Local Organizing Committee. To highlight the importance and the significance of this conference at an international level, Chronic Diseases and Injuries in Canada (CDIC) is pleased to publish this supplementary issue, which contains 70 abstracts presented at the 7th WARFS Global Conference. In the spirit the Global Conference, this collection of abstracts brings together surveillance material on risk factors, chronic diseases, infectious diseases and injuries from around the world. By making these abstracts widely available, CDIC hopes to further the conference objectives through a continued dialogue between those interested in linking risk factor surveillance to health promotion.

  6. The Breadboard Model of the LISA Telescope Assembly

    NASA Astrophysics Data System (ADS)

    Lucarelli, Stefano; Scheulen, Dietmar; Kemper, Daniel; Sippel, Rudolf; Ende, David

    2012-07-01

    The primary goal of the LISA mission is the detection of gravitational waves from astronomical sources in a frequency range of 10-4 to 1 Hz. This requires operational stabilities in the picometer range as well as highly predictable mechanical distortions upon cooling down, outgassing in space, and gravity release. In March 2011 ESA announced a new way forward for the L-class candidate missions, including LISA. ESA and the scientific community are now studying options for European-only missions that offer a significant reduction of the costs, while maintaining their core science objectives. In the context of this reformulation exercise LISA has become the New Gravitational wave Observatory (NGO) [1]. Despite this reformulation, the need for dimensional stability in the picometer range remains valid, and ESA have continued the corresponding LISA Technology Development Activities (TDA’s) also in view of NGO. In such frame Astrium GmbH and xperion (Immenstaad/Friedrichshafen, Germany) have designed and manufactured an ultra-stable CFRP breadboard of the LISA telescope in order to experimentally demonstrate that the structure and the M1 & M2 mirror mounts are fulfilling the LISA requirements in the mission operational thermal environment. Suitable techniques to mount the telescope mirrors and to support the M1 & M2 mirrors have been developed, with the aim of measuring a system CTE of less than 10-7 K-1 during cooling down to -80 °C. Additionally to the stringent mass and stiffness specifications, the required offset design makes the control of relative tilts and lateral displacements between the M1 and M2 mirrors particularly demanding. The thermo-elastic performance of the telescope assembly is going to be experimentally verified by TNO (Delft, The Netherlands) starting from the second half of 2012. This paper addresses challenges faced in the design phase, and shows the resulting hardware.

  7. LISA Technology Development, Risk Reduction and Mission Formulation at NASA

    NASA Astrophysics Data System (ADS)

    Stebbins, Robin; Ziemer, John; Livas, Jeffrey; Ira Thorpe, James; Merkowitz, Stephen

    The Laser Interferometer Space Antenna (LISA) is a joint ESA-NASA project to design, build and operate a space-based gravitational wave detector based on a laser interferometer. LISA relies on several technologies that are either new to spaceflight or must perform at levels not previously demonstrated in a spaceflight environment. The ESA-led LISA Pathfinder mission is the main effort to demonstrate LISA technology. NASA also supports complementary ground-based technology development and risk reduction activities. This presentation will report the status of NASA work on micronewton thrusters, the telescope, the optical pointing subsystem and mission formulation. More details on some of these topics will be given in posters. Other talks and posters will describe NASA-supported work on the laser subsystem, the phasemeter, and aspects of the interferometry. Two flight-qualified clusters of four colloid micronewton thrusters, each capable of thrust levels between 5 and 30 µN with a resolution ¡0.1 µN and a thrust noise ¡0.1 µN/sqrtHz (0.001 to 4 Hz), have been integrated onto the LISA Pathfinder spacecraft. The complementary ground-based development focuses on lifetime demonstration. Laboratory verification of failure models and accelerated life tests are just getting started. LISA needs a 40 cm diameter, afocal telescope for beam expansion/reduction that maintains an optical pathlength stability of 1 pm/sqrtHz in an extremely stable thermal environment. A mechanical prototype of a silicon carbide primary-secondary structure has been fabricated for stability testing. Two optical assemblies must point at different distant spacecraft with nanoradian accuracy over 1° annual variation in the angle between the distant spacecraft. A candidate piezo-inchworm actuator is being tested in a suitable testbed. In addition to technology development, NASA has carried out several studies in support of the mission formulation. The results of systems engineering work on flight

  8. The result of Venus Orbit Insertion of Akatsuki on December 7th, 2015

    NASA Astrophysics Data System (ADS)

    Sugiyama, K. I.; Nakamura, M.; Imamura, T.; Ishii, N.; Abe, T.; Kawakatsu, Y.; Hirose, C.; Satoh, T.; Suzuki, M.; Ueno, M.; Yamazaki, A.; Iwagami, N.; Watanabe, S.; Taguchi, M.; Fukuhara, T.; Takahashi, Y.; Yamada, M.; Imai, M.; Ohtsuki, S.; Uemizu, K.; Hashimoto, G. L.; Takagi, M.; Matsuda, Y.; Ogohara, K.; Sato, N.; Kasaba, Y.; Kouyama, T.; Hirata, N.; Nakamura, R.; Yamamoto, Y.; Horinouchi, T.; Yamamoto, M.; Hayashi, Y. Y.; Nakatsuka, J.; Kashimura, H.; Sakanoi, T.; Ando, H.; Murakami, S. Y.; Sato, T.; Takagi, S.; Nakajima, K.; Peralta, J.; Lee, Y. J.

    2015-12-01

    Japan launched Venus Climate Orbiter 'Akatsuki' (JAXA's mission code name: PLANET-C) to observe the dynamics of the Venus atmosphere globally and clarify the mechanism of the atmospheric circulation. The launch was on May 21st , 2010 from the Tanegashima Space Center. The cruise to Venus was smooth, however, the first Venus Orbit Insertion (VOI) trial on December 7th, 2010 tuned out to be a failure. Later Akatsuki has been orbiting the sun. Fortunately we keep the spacecraft in a healthy condition and surprisingly we have found another chance to let this spacecraft to meet Venus in 2015. Next VOI trial will be done on December 7th, 2015 and we report the result of this operation at this AGU meeting. This mission is planed to answer the question described below. The radius of the Earth and Venus are almost the same. In addition the radiation from the sun is also almost the same. The climates of these planets, however, are much different. For example, the strong zonal wind is observed on Venus with the period of 4 days, where Venus rotates westward with the period of 243 days. The wind speed is about 100 m s-1. This is called super rotation. We will investigate from data from Akatsuki what attributes to the difference of the climates between Earth and Venus. AKATSUKI was designed for remote sensing from an equatorial, elliptical orbit to tract the atmospheric motion at different altitudes using 5 cameras (3xIR, UV, Visible) and by the radio occultation technique. The first VOI has failed due to a malfunction of the propulsion system. The check valve between the helium tank and the fuel tank was blocked by an unexpected salt formation during the cruising from the Earth to Venus. As a result the main engine (orbital maneuvering engine, OME) became oxidizer-rich and fuel-poor condition, which led to an abnormal combustion in the engine with high temperature, and finally the engine was broken. We decide to use RCS thrusters for Trajectory Control Maneuvers' (TCMs) and

  9. LISA and NASA's Physics of the Cosmos Theme

    NASA Technical Reports Server (NTRS)

    Stebbins, Robin T.

    2008-01-01

    In the past year, the LISA Project at NASA has completed a major review and has thoroughly reviewed its cost estimates. This talk will summarize the conclusions of the Beyond Einstein Program Assessment, and review the main conclusions of the cost estimation work done at NASA, including reduced mission concepts. Astro2010, the decadal review which sets priorities for astronomy and astrophysics projects in the U.S., is getting organized. Preparing for and participating in Astro2010 will be a crucial activity for the NASA side of the LISA Project in thc next 18 months.

  10. The LISA PathFinder DMU Software, a Global Overview

    NASA Astrophysics Data System (ADS)

    Gesa, L.; Martin, V.; Conchillo, A.; Lobo, A.; Lloro, I.

    2013-01-01

    During the last 6 years, the IEEC software team has developed the Data Management Unit (DMU) software. It is a critical piece of engineering in the Lisa Pathfinder mission, in charge of the primary processing of data generated by the Phasemeter, acting also as an interface between the whole LISA Technology Package (LTP) and the On-Board Computer (OBC). It also manages and controls the diagnostics systems (Heaters, coils, magnetometers, radiation monitor, thermometers). This article briefly summarizes all the work performed, describing the complex environment built around the application generation.

  11. [TNM classification of breast cancer: changes and comments on the 7th edition].

    PubMed

    Sinn, H-P; Helmchen, B; Wittekind, C H

    2010-09-01

    The 7th edition of the TNM classification includes only minor changes in the main TNM categories for breast cancer. Only ductal and lobular carcinoma in situ (DCIS, LCIS), and isolated Paget's disease of the nipple are classified as pTis, but not precursor lesions such as atypical ductal or lobular hyperplasia (ADH, ALH). AJCC emphasizes that microscopic measurement is the most accurate and preferred method to determine pT in small invasive cancers and stresses the importance of strict adherence to criteria for T4 cancers. For better distinction from micrometastases in regional lymph nodes, small clusters of cells not greater than 0.2 mm, or nonconfluent or nearly confluent clusters of cells not exceeding 200 cells in a single histologic lymph node cross section are classified as isolated tumour cells (pN0(i+)). The pN classification has otherwise remained unchanged. In the setting of patients having received neoadjuvant therapy, ypT1-ypT3 is based on the total extent of viable tumour cells, irrespective of tumour regression. Stage I breast tumours have been subdivided into Stage IA and Stage IB; Stage IB includes small tumours (TI) with lymph node micrometastases (N1mi). These changes and clarifications will contribute to maintaining the clinical and prognostic relevance of TNM in breast cancer.

  12. Boston Edison and LG&E win 7th annual substation design contest

    SciTech Connect

    Beaty, W.

    1996-07-01

    Boston`s Edison`s Network Station 53 won First Place in the engineering/operations category of Electric Light & Power`s 7th annual substation design contest. Station 53 also took Second Place in the aesthetic design category. Boston Edison is no stranger to the contest, having won top honors in the aesthetic category in the very first contest in 1990. That same year, Boston took Second Place in engineering/operations design and Third Place in aesthetic design. Station 53 occupies a 12,074-square-foot site in the heart of the Boston financial district. It replaces an existing station where the land was required for Boston`s Central Artery project. Great care was taken to ensure that Station 53 would blend into the cityscape and be pleasing to the eye. The architectural treatment was designed by the Boston Anderson-Nichols & Company Inc., in cooperation with the Boston Redevelopment Authority. The latest in engineering technology was utilized to guarantee reliability, maintain the highest service quality and provide capacity for future load growth in the downtown area. Station 53 is supplied by two underground 115-kV pipe-type transmission cables. Unattended and remotely operated, Station 53 has the capability of sectionalizing the 115-kV power supply by remote control to isolate the faulted sections.

  13. The UF Torsion Pendulum, a LISA Technology Testbed: Sensing System and Initial Results

    NASA Astrophysics Data System (ADS)

    Chilton, Andrew; Shelley, Ryan; Olatunde, Taiwo; Ciani, Giacomo; Conklin, John W.; Mueller, Guido

    2015-05-01

    The upcoming LISA Pathfinder mission will test the Gravitational Reference Sensor and the Disturbance Reduction System for a future LISA-like space mission. While LISA Pathfinder is expected to show that the technology for LISA exists and meets the LISA requirements, it is likely that LISA Pathfinder will also reveal areas where future improvements can be made and might be necessary. Some of these are already well known (such as the discharging system). After all, the technology for LISA Pathfinder was frozen about 10 years ago or about 30 years before a LISA-like mission will be launched. The case for continued testing and development of the technology is clear. The University of Florida is currently building a torsion pendulum-based test facility to explore new techniques and also to develop a base in the United States for state-of-the-art Gravitational Reference Sensor technologies.

  14. Ongoing problems concerning 7th TNM Staging System and Proposals for 8th TNM Staging System of Gastric Cancer

    PubMed Central

    Ureyen, Orhan; Meral, Ulvi Mehmet

    2016-01-01

    Because of different prognosis of gastric cancer patients with the same T and N stages, the impossibility of N3 staging in patients with fewer than 15 removed lymph nodes, and the presence of stage migration phenomenon, the 6th edition TNM Staging System for gastric cancer was updated to the 7th edition TNM staging system in 2009. Despite some opposing views, the superiority of the 7th edition TNM staging system compared to the 6th has been demonstrated in many studies. However, there are doubts about the 7th edition that it will reduce the stage migration phenomenon. The most important problem about the 7th TNM staging system is regarding subgroups N3a and N3b. The separation of N3 stage as N3a and N3b does not contribute to the TNM staging system. In conclusion, separate usage of N3a and N3b subgroups in the TNM staging system should be considered in the creation phase of the 8th edition. PMID:28053675

  15. How 7th Graders Are Using Asynchronous Resources in an Online Science Course: A Mixed Methods Study

    ERIC Educational Resources Information Center

    Schafer-Mayse, Diane L.

    2013-01-01

    In this study 7th grade students were observed completing a series of lessons in an online science course to explore their thinking and strategies for using curriculum resources for learning, to explore their thinking and strategies for self-assessing their readiness for lesson assessment, and to explore the relationship between resource use and…

  16. Cultivating Environmental Virtue among 7th and 8th Graders in an Expeditionary Learning Outward Bound School

    ERIC Educational Resources Information Center

    Martin, Bruce; Bright, Alan; Cafaro, Philip; Mittelstaedt, Robin; Bruyere, Brett

    2008-01-01

    This study attempted to assess the development of environmental virtue in 7th and 8th grade students in an Expeditionary Learning Outward Bound school. The purpose of this study was twofold. First, the researchers were interested in introducing a virtue ethics perspective into their teaching of environmental ethics. Second, the researchers were…

  17. A Detection Pipeline for Galactic Binaries in LISA Data

    NASA Technical Reports Server (NTRS)

    Littenberg, Tyson B.

    2012-01-01

    The Galaxy is suspected to contain hundreds of millions of binary white dwarf systems, a large fraction of which will have sufficiently small orbital period to emit gravitational radiation in band for space-based gravitational wave detectors such as the Laser Interferometer Space Antenna (LISA). LISA's main science goal is the detection of cosmological events (supermassive black hole mergers) etc.) however the gravitational signal from the galaxy will be the dominant contribution to the data - including instrumental noise - over approximately two decades in frequency. The catalogue of detectable binary systems will serve as an unparalleled means of studying the Galaxy. Furthermore, to maximize the scientific return from the mission, the data must be "cleansed" of the galactic foreground. We will present an algorithm that can accurately resolve and subtract greater than or equal to 10000 of these sources from simulated data supplied by the Mock LISA Data Challenge Task Force. Using the time evolution of the gravitational wave frequency, we will reconstruct the position of the recovered binaries and show how LISA will sample the entire compact binary population in the Galaxy.

  18. Mona Lisa is always happy – and only sometimes sad

    PubMed Central

    Liaci, Emanuela; Fischer, Andreas; Heinrichs, Markus; van Elst, Ludger Tebartz; Kornmeier, Jürgen

    2017-01-01

    The worldwide fascination of da Vinci’s Mona Lisa has been dedicated to the emotional ambiguity of her face expression. In the present study we manipulated Mona Lisa’s mouth curvature as one potential source of ambiguity and studied how a range of happier and sadder face variants influences perception. In two experimental conditions we presented different stimulus ranges with different step sizes between stimuli along the happy-sad axis of emotional face expressions. Stimuli were presented in random order and participants indicated the perceived emotional face expression (first task) and the confidence of their response (second task). The probability of responding ‘happy’ to the original Mona Lisa was close to 100%. Furthermore, in both conditions the perceived happiness of Mona Lisa variants described sigmoidal functions of the mouth curvature. Participants’ confidence was weakest around the sigmoidal inflection points. Remarkably, the sigmoidal functions, as well as confidence values and reaction times, differed significantly between experimental conditions. Finally, participants responded generally faster to happy than to sad faces. Overall, the original Mona Lisa seems to be less ambiguous than expected. However, perception of and reaction to the emotional face content is relative and strongly depends on the used stimulus range. PMID:28281547

  19. LISA Pathfinder: the geodesy explorer testing alternative theories of gravity

    NASA Astrophysics Data System (ADS)

    Armano, Michele

    The LISA Pathfinder spacecraft by ESA is on schedule to fly by autumn 2015. Implementing a high precision free-fall in-flight system near a Lagrangian point, the mission relies on technologies never used before in space environments and crucial to gravitational waves observatories. The core instrument configuration makes LISA Pathfinder a gradiometer of unprecedented sensitivity. The designated orbit places it in position to further cruise through a volume of space where Newtonian pulls compensate and the Newtonian acceleration is close to zero. In the global picture that sees several dark matter/energy models and many theories at work to match observations, the free-fall specialist LISA Pathfinder can directly explore gravity at its alleged depart from the Newtonian regime, realizing a null dynamical test so far missing between astrophysical measurements and planetary tests. We will explicitly consider MOND theories as a test canvas and show that without further modifications the LISA Pathfinder instrument could sample several scales of the Newtonian-MONDian regime. We shall highlight the science case, the current experiment, the measurement design and the related data analysis.

  20. Time domain simulations of arm locking in LISA

    SciTech Connect

    Thorpe, J. I.; Livas, J.; Maghami, P.

    2011-06-15

    Arm locking is a proposed laser frequency stabilization technique for the Laser Interferometer Space Antenna (LISA), a gravitational-wave observatory sensitive in the milliHertz frequency band. Arm locking takes advantage of the geometric stability of the triangular constellation of three spacecraft that compose LISA to provide a frequency reference with a stability in the LISA measurement band that exceeds that available from a standard reference such as an optical cavity or molecular absorption line. We have implemented a time-domain simulation of a Kalman-filter-based arm-locking system that includes the expected limiting noise sources as well as the effects of imperfect a priori knowledge of the constellation geometry on which the design is based. We use the simulation to study aspects of the system performance that are difficult to capture in a steady-state frequency-domain analysis such as frequency pulling of the master laser due to errors in estimates of heterodyne frequency. We find that our implementation meets requirements on both the noise and dynamic range of the laser frequency with acceptable tolerances and that the design is sufficiently insensitive to errors in the estimated constellation geometry that the required performance can be maintained for the longest continuous measurement intervals expected for the LISA mission.

  1. Time domain simulations of arm locking in LISA

    NASA Astrophysics Data System (ADS)

    Thorpe, J. I.; Maghami, P.; Livas, J.

    2011-06-01

    Arm locking is a proposed laser frequency stabilization technique for the Laser Interferometer Space Antenna (LISA), a gravitational-wave observatory sensitive in the milliHertz frequency band. Arm locking takes advantage of the geometric stability of the triangular constellation of three spacecraft that compose LISA to provide a frequency reference with a stability in the LISA measurement band that exceeds that available from a standard reference such as an optical cavity or molecular absorption line. We have implemented a time-domain simulation of a Kalman-filter-based arm-locking system that includes the expected limiting noise sources as well as the effects of imperfect a priori knowledge of the constellation geometry on which the design is based. We use the simulation to study aspects of the system performance that are difficult to capture in a steady-state frequency-domain analysis such as frequency pulling of the master laser due to errors in estimates of heterodyne frequency. We find that our implementation meets requirements on both the noise and dynamic range of the laser frequency with acceptable tolerances and that the design is sufficiently insensitive to errors in the estimated constellation geometry that the required performance can be maintained for the longest continuous measurement intervals expected for the LISA mission.

  2. "Multiplication Is for White People": An Interview with Lisa Delpit

    ERIC Educational Resources Information Center

    Sokolower, Jody

    2012-01-01

    In the introduction to her new book, ""Multiplication Is for White People": Raising Expectations for Other People's Children," Lisa Delpit describes her response when Diane Ravitch asked her why she hasn't spoken out against the devastation of public schools in her home state of Louisiana and the efforts to make New Orleans the national model. She…

  3. Testing new technologies for the LISA Gravitational Reference Senso

    NASA Astrophysics Data System (ADS)

    Conklin, John; Chilton, Andrew; Olatunde, Taiwo; Apple, Stephen; Ciani, Giacomo; Mueller, Guido

    2015-01-01

    LISA will directly observe low-frequency gravitational waves emitted by sources ranging from super-massive black hole mergers to compact galactic binaries. A laser interferometer will measure picometer changes in the distances between free falling test masses separated by millions of kilometers. A test mass and its associated sensing, actuation, charge control and caging subsystems are referred to as a gravitational reference sensor (GRS). The demanding acceleration noise requirement of < 3×10-15 m/sec2Hz1/2 for the LISA GRS has motivated a rigorous testing campaign in Europe and a dedicated technology mission, LISA Pathfinder, scheduled for launch in the summer of 2015. At the University of Florida we are developing a nearly thermally noise limited torsion pendulum for testing GRS technology enhancements and for understanding the dozens of acceleration noise sources that affect the performance of the GRS. This experimental facility is based on the design of a similar facility at the University of Trento, and consists of a vacuum enclosed torsion pendulum that suspends mock-ups of the LISA test masses, surrounded by electrode housings. Some of the technologies that will be demonstrated by this facility include a novel TM charge control scheme based on ultraviolet LEDs, an all-optical TM position and attitude sensor, and drift mode operation. This presentation will describe the design of the torsion pendulum facility, its current acceleration noise performance, and the status of the GRS technologies under development.

  4. 240 nm UV LEDs for LISA test mass charge control

    NASA Astrophysics Data System (ADS)

    Olatunde, Taiwo; Shelley, Ryan; Chilton, Andrew; Serra, Paul; Ciani, Giacomo; Mueller, Guido; Conklin, John

    2015-05-01

    Test Masses inside the LISA Gravitational Reference Sensor must maintain almost pure geodesic motion for gravitational waves to be successfully detected. LISA requires residual test mass accelerations below 3 fm/s2/√Hz at all frequencies between 0.1 and 3 mHz. One of the well-known noise sources is associated with the charges on the test masses which couple to stray electrical potentials and external electromagnetic fields. LISA Pathfinder will use Hg-discharge lamps emitting mostly around 254 nm to discharge the test masses via photoemission in its 2015/16 flight. A future LISA mission launched around 2030 will likely replace the lamps with newer UV-LEDs. Presented here is a preliminary study of the effectiveness of charge control using latest generation UV-LEDs which produce light at 240 nm with energy above the work function of pure Au. Their lower mass, better power efficiency and small size make them an ideal replacement for Hg lamps.

  5. In vitro Comparative Evaluation of Tensile Bond Strength of 6th, 7th and 8th Generation Dentin Bonding Agents

    PubMed Central

    Kamble, Suresh S; Kandasamy, Baburajan; Thillaigovindan, Ranjani; Goyal, Nitin Kumar; Talukdar, Pratim; Seal, Mukut

    2015-01-01

    Background: Newer dentin bonding agents were developed to improve the quality of composite restoration and to reduce time consumption in its application. The aim of the present study was to evaluate tensile bond strength of 6th, 7th and 8th generation bonding agents by in vitro method. Materials and Methods: Selected 60 permanent teeth were assigned into 20 in each group (Group I: 6th generation bonding agent-Adper SE plus 3M ESPE, Group II: 7th generation bonding agent-G-Bond GC Corp Japan and Group III: 8th generation dentin adhesives-FuturaBond, DC, Voco, Germany). With high-speed diamond disc, coronal dentin was exposed, and selected dentin bonding agents were applied, followed by composite restoration. All samples were saved in saline for 24 h and tensile bond strength testing was done using a universal testing machine. The obtained data were tabulated and statistically analyzed using ANOVA test. Results: The tensile bond strength readings for 6th generation bonding agent was 32.2465, for 7th generation was 31.6734, and for 8th-generation dentine bonding agent was 34.74431. The highest tensile bond strength was seen in 8th generation bonding agent compared to 6th and 7th generation bonding agents. Conclusion: From the present study it can be conclude that 8th generation dentine adhesive (Futura DC, Voco, Germany) resulted in highest tensile bond strength compared to 6th (Adper SE plus, 3M ESPE) and 7th generation (G-Bond) dentin bonding agents. PMID:26028901

  6. The Aegean in the Early 7th Millennium BC: Maritime Networks and Colonization.

    PubMed

    Horejs, B; Milić, B; Ostmann, F; Thanheiser, U; Weninger, B; Galik, A

    The process of Near Eastern neolithization and its westward expansion from the core zone in the Levant and upper Mesopotamia has been broadly discussed in recent decades, and many models have been developed to describe the spread of early farming in terms of its timing, structure, geography and sociocultural impact. Until now, based on recent intensive investigations in northwestern and western Anatolia, the discussion has mainly centred on the importance of Anatolian inland routes for the westward spread of neolithization. This contribution focuses on the potential impact of east Mediterranean and Aegean maritime networks on the spread of the Neolithic lifestyle to the western edge of the Anatolian subcontinent in the earliest phases of sedentism. Employing the longue durée model and the concept of 'social memory', we will discuss the arrival of new groups via established maritime routes. The existence of maritime networks prior to the spread of farming is already indicated by the high mobility of Epipalaeolithic/Mesolithic groups exploring the Aegean and east Mediterranean seas, and reaching, for example, the Cyclades and Cyprus. Successful navigation by these early mobile groups across the open sea is attested by the distribution of Melian obsidian. The potential existence of an additional Pre-Pottery Neolithic (PPN) obsidian network that operated between Cappadocia/Cilicia and Cyprus further hints at the importance of maritime coastal trade. Since both the coastal and the high seas networks were apparently already well established in this early period, we may further assume appropriate knowledge of geographic routes, navigational technology and other aspects of successful seafaring. This Mesolithic/PPN maritime know-how package appears to have been used by later groups, in the early 7th millennium calBC, exploring the centre of the Anatolian Aegean coast, and in time establishing some of the first permanent settlements in that region. In the present paper, we

  7. Silicon Carbide Telescope Investigations for the LISA Mission

    NASA Technical Reports Server (NTRS)

    Sanjuan, J.; Spannagel, R.; Braxmaier, C.; Korytov, D.; Mueller, G.; Preston, A.; Livas, J.

    2013-01-01

    Space-based gravitational wave (GW) detectors are conceived to detect GWs in the low frequency range (mili-Hertz) by measuring the distance between free-falling proof masses in spacecraft (SC) separated by 5 Gm. The reference in the last decade has been the joint ESA-NASA mission LISA. One of the key elements of LISA is the telescope since it simultaneously gathers the light coming from the far SC (approximately or equal to 100 pW) and expands, collimates and sends the outgoing beam (2 W) to the far SC. Demanding requirements have been imposed on the telescope structure: the dimensional stability of the telescope must be approximately or equal to 1pm Hz(exp-1/2) at 3 mHz and the distance between the primary and the secondary mirrors must change by less than 2.5 micrometer over the mission lifetime to prevent defocussing. In addition the telescope structure must be light, strong and stiff. For this reason a potential on-axis telescope structure for LISA consisting of a silicon carbide (SiC) quadpod structure has been designed, constructed and tested. The coefficient of thermal expansion (CTE) in the LISA expected temperature range has been measured with a 1% accuracy which allows us to predict the shrinkage/expansion of the telescope due to temperature changes, and pico-meter dimensional stability has been measured at room temperature and at the expected operating temperature for the LISA telescope (around -6[deg]C). This work is supported by NASA Grants NNX10AJ38G and NX11AO26G,

  8. Precision Electric Propulsion For The ST7 And LISA Missions

    NASA Astrophysics Data System (ADS)

    Ziemer, John; Hruby, V.; Randolph, T.; Spence, D.; Demmons, N.; Roy, T.; Ehrbar, E.; Zwahlen, J.; Martin, R.; Connolly, W.; Franklin, G.

    2010-01-01

    The Jet Propulsion Laboratory (JPL) has delivered two flight-qualified Colloid Micro-Newton Thruster (CMNT) systems to the European Space Agency (ESA) for a flight demonstration on LISA Pathfinder. The CMNTs will provide precise spacecraft control for the drag-free technology demonstration mission, Space Technology 7 (ST7). The ST7 mission is sponsored by the NASA New Millennium Program and will demonstrate precision formation flying technologies for future missions such as LISA. The ST7 disturbance reduction system (DRS) will be part of the LISA Pathfinder mission using the European gravitational reference sensor (GRS), part of the LISA Technology Package (LTP). To achieve the nanometer-level precision control requirements, each of eight thruster systems is required to provide thrust between 5 and 30 μN with resolution ≤0.1 μN and thrust noise ≤0.1 μN/√Hz. Developed by Busek Company Inc., with support from JPL in design and testing, the CMNT has been developed over the last six years into a flight-ready and flight-qualified microthruster system, the first of its kind. Flight-unit qualification tests have included vibration and thermal vacuum environmental testing, as well as performance verification and acceptance tests. All tests have been completed successfully prior to delivery to JPL. Delivery of the first flight unit occurred in February of 2008 with the second unit following in May of 2008. Since arrival at JPL, the units have successfully passed through mass distribution, magnetic, and EMI/EMC measurements and tests as part of the integration and test activities including the integrated avionics unit (IAU). Flight software sequences have been tested and validated with the full flight DRS instrument successfully. Delivery of the DRS to ESA for integration into the LISA Pathfinder spacecraft was completed in September of 2009 with a planned launch and flight demonstration in 2011.

  9. Active Thermal Control Experiments for LISA Ground Verification Testing

    NASA Astrophysics Data System (ADS)

    Higuchi, Sei; DeBra, Daniel B.

    2006-11-01

    The primary mission goal of LISA is detecting gravitational waves. LISA uses laser metrology to measure the distance between proof masses in three identical spacecrafts. The total acceleration disturbance to each proof mass is required to be below 3 × 10-15 m/s2√Hz . Optical path length variations on each optical bench must be kept below 40 pm/√Hz over 1 Hz to 0.1 mHz. Thermal variations due to, for example, solar radiation or temperature gradients across the proof mass housing will distort the spacecraft causing changes in the mass attraction and sensor location. We have developed a thermal control system developed for the LISA gravitational reference sensor (GRS) ground verification testing which provides thermal stability better than 1 mK/√Hz to f < 1 mHz and which by extension is suitable for in-flight thermal control for the LISA spacecraft to compensate solar irradiation. Thermally stable environment is very demanded for LISA performance verification. In a lab environment specifications can be met with considerable amount of insulation and thermal mass. For spacecraft, the very limited thermal mass calls for an active control system which can meet disturbance rejection and stability requirements simultaneously in the presence of long time delay. A simple proportional plus integral control law presently provides approximately 1 mK/√Hz of thermal stability for over 80 hours. Continuing development of a model predictive feed-forward algorithm will extend performance to below 1 mK/√Hz at f < 1 mHz and lower.

  10. Rapid prototyping and evaluation of programmable SIMD SDR processors in LISA

    NASA Astrophysics Data System (ADS)

    Chen, Ting; Liu, Hengzhu; Zhang, Botao; Liu, Dongpei

    2013-03-01

    With the development of international wireless communication standards, there is an increase in computational requirement for baseband signal processors. Time-to-market pressure makes it impossible to completely redesign new processors for the evolving standards. Due to its high flexibility and low power, software defined radio (SDR) digital signal processors have been proposed as promising technology to replace traditional ASIC and FPGA fashions. In addition, there are large numbers of parallel data processed in computation-intensive functions, which fosters the development of single instruction multiple data (SIMD) architecture in SDR platform. So a new way must be found to prototype the SDR processors efficiently. In this paper we present a bit-and-cycle accurate model of programmable SIMD SDR processors in a machine description language LISA. LISA is a language for instruction set architecture which can gain rapid model at architectural level. In order to evaluate the availability of our proposed processor, three common baseband functions, FFT, FIR digital filter and matrix multiplication have been mapped on the SDR platform. Analytical results showed that the SDR processor achieved the maximum of 47.1% performance boost relative to the opponent processor.

  11. FOREWORD: 7th Symposium on Vacuum-based Science and Technology (SVBST2013)

    NASA Astrophysics Data System (ADS)

    Gulbiński, W.

    2014-11-01

    These are the proceedings of the 7th Symposium on Vacuum based Science and Technology organized in Kołobrzeg (PL) on November 19-21, 2013 by the Institute of Technology and Education, Koszalin University of Technology and the Clausius Tower Society under auspices of the Polish Vacuum Society (PTP) and the German Vacuum Society (DVG) and in collaboration with the BalticNet PlasmaTec and the Society of Vacuum Coaters (SVC). It was accompanied by the 12-th Annual Meeting of the German Vacuum Society. The mission of the Symposium is to provide a forum for presentation and exchange of expertise and research results in the field of vacuum and plasma science. After already six successful meetings organized alternately in Poland and Germany our goal is to continue and foster cooperation within the vacuum and plasma science community. This year, the Rudolf-Jaeckel Prize, awarded by the DVG for outstanding achievements in the field of vacuum based sciences, was presented to Dr Ute Bergner, president of the VACOM Vakuum Komponenten & Messtechnik GmbH and a member of our community. The full-day course organized in the framework of the Educational Program by the Society of Vacuum Coaters (SVC) and entitled: An Introduction to Physical Vapor Deposition (PVD) Processes was held on November 18, 2013 as a satellite event of the Symposium. The instructor was Prof. Ismat Shah from Delaware University (US). The Clausius Session, already traditionally organized during the Symposium was addressed this year to young generation. We invited our young colleagues to attend a series of educational lectures reporting on achievements in graphene science, scanning probe microscopy and plasma science. Lectures were given by: Prof. Jacek Baranowski from the Institute of Electronic Materials Technology in Warsaw, Prof. Teodor Gotszalk from the Wroclaw University of Technology and Prof. Holger Kersten from the Christian Albrechts University in Kiel. The Symposium was accompanied by an industry

  12. LISA Technology Development and Risk Reduction at NASA

    NASA Technical Reports Server (NTRS)

    Stebbins, Robin T.

    2010-01-01

    The Laser Interferometer Space Antenna (LISA) is a joint ESA-NASA project to design, build and operate a space-based gravitational wave detector based on a laser interferometer. LISA relies on several technologies that are either new to spaceflight or must perform at levels not previously demonstrated in a spaceflight environment. The ESA-led LISA Pathfinder mission is the main effort to demonstrate LISA technology. NASA also supports complementary ground-based technology development and risk reduction activities. This presentation will report the status of NASA work on micronewton thrusters, the telescope, the optical pointing subsystem and mission formulation. More details on some of these topics will be given in posters. Other talks and posters will describe NASA-supported work on the laser subsystem, the phasemeter, and aspects of the interferometry. Two flight-qualified clusters of four colloid micronewton thrusters, each capable of thrust Levels between 5 and 30 microNewton with a resolution less than 0.l microNewton and a thrust noise less than 0.1 microNewton/vHz (0.001 to 4 Hz), have been integrated onto the LISA Pathfinder spacecraft. The complementary ground-based development focuses on lifetime demonstration. Laboratory verification of failure models and accelerated life tests are just getting started. LISA needs a 40 cm diameter, afocal telescope for beam expansion/reduction that maintains an optical pathlength stability of approximately 1 pm/vHz in an extremely stable thermal environment. A mechanical prototype of a silicon carbide primary-secondary structure has been fabricated for stability testing. Two optical assemblies must point at different distant spacecraft with nanoradian accuracy over approximately 1 degree annual variation in the angle between the distant spacecraft. A candidate piezo-inchworm actuator is being tested in a suitable testbed. In addition to technology development, NASA has carried out several studies in support of the

  13. [The IASLC lung cancer staging project. Comparing the current 6(th) TNM edition with the proposed 7(th) edition].

    PubMed

    Carvalho, Lina; Cardoso, Edgar; Nunes, Henrique; Baptista, Victor; Gomes, Ana; Couceiro, Patrícia

    2009-01-01

    The future 7th edition of TNM classification for lung cancer will be published in 2009 and comprises the IASLC recommendations for TNM parameters. The general staging of lung cancer includes the new parameters: reclassification of tumours larger than 7 cm from T2 to T3; extra tumoral nodules will change their category to T3, T4 and M1 when in the same, ipsilateral or contralateral lobe, respectively; pleural effusion will be M1a. With these alterations, cases staged as IB - T2b N0 M0 will be IIA, cases staged IIB - T2a N1 M0 will be IIA and cases IIIB- T4 N0- -1 M0 will be IIIA. The 7(th) TNM edition recommendations were applied to 203 broncho -pulmonary carcinomas, concerning epidermoid carcinomas (83) and adenocarcinomas (120) registered in the archive of the Serviço de Anatomia Patológica of the Hospitais da Universidade de Coimbra - Portugal, previously submitted to surgical resection and lymph node excision. The following alterations will be kept as the application of the future 7(th) TNM edition: 20 cases in stage IB will move to stage IIA (17) and stage IIB (3); 18 cases will change from stage IIB to stage IIA (17) and 1 case to stage IIIA; 2 cases from stage IIIB will move to stage IV; 6 cases in stage IV will move to stage IIIA (5) and 1 case to stage IIIB. In this translational adaptation from 6th to 7th TNM staging, 51 out of the 203 analysed cases change their staging, corresponding to 25.1%.

  14. *Abstracts - 7th IN-CAM Research Symposium, Evaluating CAM Practices: Effectiveness, Integration, Economics & Safety - November 2012.

    PubMed

    Boon, Heather; Verhoef, Marja J

    2012-10-23

    Abstract The following are abstracts of oral and poster presentations given at the 7th IN-CAM Research Symposium - Evaluating CAM Practices: Effectiveness, Integration, Economics & Safety, and the 4th HomeoNet Research Forum, a pre-Symposium event. The IN-CAM Research Symposium was held November 2 to 4, 2012 at the Leslie Dan Faculty of Pharmacy, University of Toronto, in Toronto, Ontario, Canada. For more information, please visit: www.incamresearch.ca.

  15. State Space Modelling and Data Analysis Exercises in LISA Pathfinder

    NASA Astrophysics Data System (ADS)

    Nofrarias, M.; Antonucci, F.; Armano, M.; Audley, H.; Auger, G.; Benedetti, M.; Binetruy, P.; Bogenstahl, J.; Bortoluzzi, D.; Brandt, N.; Caleno, M.; Cavalleri, A.; Congedo, G.; Cruise, M.; Danzmann, K.; De Marchi, F.; Diaz-Aguilo, M.; Diepholz, I.; Dixon, G.; Dolesi, R.; Dunbar, N.; Fauste, J.; Ferraioli, L.; Ferroni, V.; Fichter, W.; Fitzsimons, E.; Freschi, M.; García Marirrodriga, C.; Gerndt, R.; Gesa, L.; Gibert, F.; Giardini, D.; Grimani, C.; Grynagier, A.; Guzmán, F.; Harrison, I.; Heinzel, G.; Hewitson, M.; Hollington, D.; Hoyland, D.; Hueller, M.; Huesler, J.; Jennrich, O.; Jetzer, P.; Johlander, B.; Karnesis, N.; Korsakova, N.; Killow, C.; Llamas, X.; Lloro, I.; Lobo, A.; Maarschalkerweerd, R.; Madden, S.; Mance, D.; Martin, V.; Mateos, I.; McNamara, P.; Mendes, J.; Mitchell, E.; Nicolodi, D.; Perreur-Lloyd, M.; Plagnol, E.; Prat, P.; Ramos-Castro, J.; Reiche, J.; Romera Perez, J. A.; Robertson, D.; Rozemeijer, H.; Russano, G.; Schleicher, A.; Shaul, D.; Sopuerta, C. F.; Sumner, T. J.; Taylor, A.; Texier, D.; Trenkel, C.; Tu, H. B.; Vitale, S.; Wanner, G.; Ward, H.; Waschke, S.; Wass, P.; Wealthy, D.; Wen, S.; Weber, W.; Ziegler, T.; Zweifel, P.

    2013-01-01

    LISA Pathfinder is a mission planned by the European Space Agency (ESA) to test the key technologies that will allow the detection of gravitational waves in space. The instrument on-board, the LISA Technology package, will undergo an exhaustive campaign of calibrations and noise characterisation campaigns in order to fully describe the noise model. Data analysis plays an important role in the mission and for that reason the data analysis team has been developing a toolbox which contains all the functionality required during operations. In this contribution we give an overview of recent activities, focusing on the improvements in the modelling of the instrument and in the data analysis campaigns performed both with real and simulated data.

  16. [Mona Lisa syndrome: idiopathic facial paralysis during pregnancy].

    PubMed

    Hellebrand, M-C; Friebe-Hoffmann, U; Bender, H G; Kojda, G; Hoffmann, T K

    2006-08-01

    Mona Lisa has been pregnant shortly before the famous painting of Leonardo da Vinci was created (1503-1506). Recently, it has been speculated that Mona Lisa's famous smile is caused by facial muscle contracture and/or synkinesis after Bell's palsy with incomplete nerval regeneration. During pregnancy the incidence of Bell's palsy is increased up to 3.3 times compared to nonpregnant women. The etiology, associated factors as well as various treatment options aiming at the prevention of associated complications and improving recovery of facial nerve function have intensively been evaluated over the past three decades. However, the preferred mode of therapy management, particularly in pregnant women, remains undecided. Corticosteroids may be beneficial if they are applied after the first trimester.

  17. Verification of polarising optics for the LISA optical bench.

    PubMed

    Dehne, Marina; Tröbs, Michael; Heinzel, Gerhard; Danzmann, Karsten

    2012-12-03

    The Laser Interferometer Space Antenna (LISA) is a space-based interferometric gravitational wave detector. In the current baseline design for the optical bench, the use of polarising optics is foreseen to separate optical beams. Therefore it is important to investigate the influence of polarising components on the interferometer sensitivity and validate that the required picometre stability in the low-frequency band (1 mHz - 1 Hz) is achievable. This paper discusses the design of the experiment and the implemented stabilisation loops. A displacement readout fulfilling the requirement in the whole frequency band is presented. Alternatively, we demonstrate improvement of the noise performance by implementing various algorithms in data post-processing, which leads to an additional robustness for the LISA mission.

  18. LISA-like Laser Ranging for GRACE Follow-on

    NASA Astrophysics Data System (ADS)

    Schütze, D.; Stede, G.; Müller, V.; Gerberding, O.; Mahrdt, C.; Sheard, B.; Heinzel, G.; Danzmann, K.

    2013-01-01

    The Gravity Recovery and Climate Experiment (GRACE) mission successfully demonstrated that low-orbit satellite-to-satellite tracking is a powerful tool to analyze spatial and temporal changes in Earth's gravity field. Especially hydrological mass transports are well-resolved. To continue longterm observations, a GRACE follow-on mission is planned for 2017 which will almost be an identical copy of the GRACE mission. Additionally, for technological demonstration, a Laser Ranging Interferometer is planned supplementary to the conventional microwave ranging device to potentially improve the intersatellite range measurements. The frequency band of interest for Earth gravity observations coincides with the LISA frequency band, thus LISA technology can be inherited. We describe the basic concept of the Laser Ranging Interferometer for GRACE follow-on and present a testbed to investigate its functionality and key components.

  19. Near-Earth Asteroids Detection Rate with LISA

    NASA Technical Reports Server (NTRS)

    Tricarico, P.

    2009-01-01

    The LISA space mission, designed to monitor low frequency gravitational waves, is also sensitive to passages of asteroids nearby one of its three spacecrafts. We report the expected rate of detections of asteroid passages, using the known catalog of asteroids and a modeled population. The method adopted consists of determining for each known asteroid the critical encounter distance capable of producing a detectable event, and then computing the rate of encounters within this distance. Results are then scaled to the modeled population using its differential distribution in absolute magnitude, correcting for selection effects. We find that an average of 2.0 +/- 0.1 events per year at a signal-to-noise ratio of 1 will be detected by LISA, including all the asteroids in the modeled population with absolute magnitude H < 22, roughly equivalent to all asteroids with a diameter larger than 100 m.

  20. The Status of the Mock LISA Data Challenges

    NASA Technical Reports Server (NTRS)

    Baker, John

    2009-01-01

    For the last four years, many gravitational-wave researchers around the world have participated in the Mock LISA Data Challenges (MLDCs), a program to demonstrate and encourage the development of LISA data-analysis capabilities, tools and techniques. In this poster, we present a summary of the results of MLDC 3, which was completed in 2009. During MLDC 3, 27 participants from 15 institutions successfully analyzed data sets that included Galactic binaries, coalescing spinning massive black holes, extreme-mass-ratio inspirals, cosmic-string cusp bursts and a stochastic gravitational-wave background. We also describe the technical and scientific challenges that will be addressed by future MLI)Cs, starting with MLDC 4, which is currently in progress.

  1. DaVinci's Mona Lisa entering the next dimension.

    PubMed

    Carbon, Claus-Christian; Hesslinger, Vera M

    2013-01-01

    For several of Leonardo da Vinci's paintings, such as The Virgin and Child with St Anne or the Mona Lisa, there exist copies produced by his own studio. In case of the Mona Lisa, a quite exceptional, rediscovered studio copy was presented to the public in 2012 by the Prado Museum in Madrid. Not only does it mirror its famous counterpart superficially; it also features the very same corrections to the lower layers, which indicates that da Vinci and the 'copyist' must have elaborated their panels simultaneously. On the basis of subjective (thirty-two participants estimated painter-model constellations) as well as objective data (analysis of trajectories between landmarks of both paintings), we revealed that both versions differ slightly in perspective. We reconstructed the original studio setting and found evidence that the disparity between both paintings mimics human binocular disparity. This points to the possibility that the two Giocondas together might represent the first stereoscopic image in world history.

  2. Development of a US Gravitational Wave Laser System for LISA

    NASA Technical Reports Server (NTRS)

    Camp, Jordan B.; Numata, Kenji

    2015-01-01

    A highly stable and robust laser system is a key component of the space-based LISA mission architecture.In this talk I will describe our plans to demonstrate a TRL 5 LISA laser system at Goddard Space Flight Center by 2016.The laser system includes a low-noise oscillator followed by a power amplifier. The oscillator is a low-mass, compact 10mW External Cavity Laser, consisting of a semiconductor laser coupled to an optical cavity, built by the laser vendorRedfern Integrated Optics. The amplifier is a diode-pumped Yb fiber with 2W output, built at Goddard. I will show noiseand reliability data for the full laser system, and describe our plans to reach TRL 5 by 2016.

  3. Preliminary Investigations of an Optical Assembly Tracking Mechanism for LISA

    NASA Technical Reports Server (NTRS)

    Thorpe, James Ira; Stebbins, Robin

    2010-01-01

    After injection into their specific orbits, the position of the LISA spacecraft are not actively controlled. Rather the spacecraft are allowed to passively follow their trajectories and the roughly equilateral triangular constellation is preserved. Slight variations in the orbits cause the constellation to experience both periodic and secular variations, one consequence of which is a variation in the interior angles of the constellation on the order of one degree. This variation is larger than the field of view of the LISA telescope, requiring a mechanism for each spacecraft to maintain pointing to its two companions. This Optical Assembly Tracking Mechanism (OATM) will be used to accommodate these variations while maintaining pointing at the ten nanoradian level to the far spacecraft. Here we report on a possible design for the OATM as well as initial results from a test campaign of a piezo-inchworm actuator used to drive the mechanism.

  4. [Change in short-term memory in pupils of 5-7th classes in the process of class work].

    PubMed

    Rybakov, V P; Orlova, N I

    2014-01-01

    The subject of this study was the investigation of the short-term memory (STM) of visual (SVM) and auditory (SAM) modality in boys and girls of the middle school age, as in the daytime, and during the course of the school week. The obtained data show that in pupils from the 5th to the 7th class SVM and SAM playback volume in children of both genders is significantly increased, while SVM productivity in boys from 6 - 7th classes is higher than in girls of the same age. The amplitude of day changes in SVM and SAM was found to decrease significantly with the age. In all age groups the range of daily fluctuations in short-term memory of both modalities in boys appears to be higher than in girls. In all age groups a significant part of schoolchildren was revealed to possess optimal forms of temporal organization of short-term memory: morning, day and morning-day types, in that while during the school week in pupils of 5th to 7th classes of both genders the number of optimal waveforms of curves of daily dynamics of short-term memory increases, which contributes to the optimization of their mental performance.

  5. Polarization Considerations for the Laser Interferometer Space Antenna (LISA)

    NASA Technical Reports Server (NTRS)

    Waluschka, Eugene; Pedersen, Trace R.; McNamara, Paul

    2005-01-01

    A polarization ray trace model of the Laser Interferometer Space Antenna's (LISA) optical path is being created. The model will be able to assess the effects of various polarizing elements and the optical coatings on the required picometer level interferometry. All of the computational steps are described in detail. This should eliminate any ambiguities associated with polarization ray trace modeling of interferometers and provide a basis for determining its limitations and serve as a clearly defined starting point for future improvements.

  6. ST7-DRS on LISA Pathfinder: Initial Status

    NASA Astrophysics Data System (ADS)

    Cutler, Curt; Ziemer, John; Barela, Phil; Demmons, Nathaniel; Dunn, Charles; Hruby, Vlad; Hsu, Oscar; Liepack, Otfrid; Maghami, Peiman; O'Donnell, James; Slutsky, Jacob; Thorpe, James; Romero-Wolfe, Andrew

    2016-03-01

    LISA Pathfinder (LPF), a European Space Agency Mission to demonstrate technologies for future space-based gravitational wave observatories, was launched from French Guiana on Dec 3, 2015. A payload on LPF is the NASA-provided ST7 Disturbance Reduction System (ST7-DRS). We will describe the current state of ST7-DRS, including results from the initial on-orbit commissioning and the experimental plan for the ST7-DRS operations in the summer of 2016.

  7. Conference Paper NFO-7:7th International Conference on Near-Field Optics and Related Technologies

    SciTech Connect

    Prof.Dr. Lukas Novotny

    2004-10-18

    The seventh conference in the NFO conference series, held here in Rochester, provided to be the principal forum for advances in sub-wavelength optics, near-field optical microscopy, local field enhancement, instrumental developments and the ever-increasing range of applications. This conference brought together the diverse scientific communities working on the theory and application of near-field optics (NFO) and related techniques.

  8. International Hydrogenase Conference (7th) Held at the University of Reading on August 24th to 29th 2004.

    DTIC Science & Technology

    2007-11-02

    FeFe ]Hlase Si and electrocatalysis: as good as platinum or as . . . . .. . . d e . . . . . . . ..goo as it g ts.] .... 11.40 12.00 T6. Chris Pickett PB...Asymmetric Models of the Active Site of [ FeFe ]H ase and p2 5 Electrocatalysis: As Good as Platinum or as Good as It Gets? Marcetta Y. Darensbourg...4th to 29’", 2004 T5. Asymmetric Models of the Active Site of [ FeFe ]H2ase and Electrocatalysis: As Good as Platinum or as Good as It Gets? Marcetta Y

  9. International Congress on Experimental Mechanics, 7th, Las Vegas, NV, June 8-11, 1992, Proceedings. Vols. 1 & 2

    NASA Astrophysics Data System (ADS)

    The present volume on experimental mechanics discusses composites, fatigue fracture, NDE and ultrasonic applications, and hybrid methods in experimental mechanics. Attention is given to applications in biomechanics, residual stress, measuring stresses in bolted connections, and applied/industrial applications of photoelasticity. Topics addressed include applications in electronics and material science, performance evaluation of civil structures, brittle materials and crack propagation, and transducers. Also discussed are intelligent structures, strain gages, effects of dynamic stimulus on structures, dynamic modeling, and residual stress measurement in nonmetallic materials.

  10. International Conference on Composite Structures (7th), Held in United Kingdom, July 1993. Volume 25, Numbers 1 - 4

    DTIC Science & Technology

    1993-07-01

    settling, time of’ the flexural vibrations was 199cs J. -. io~ 1 on100-9o..I4(~N’ -IX initiated, with the results to be presented in the 5. [ Ehlers . S. M...W.OIý1 ank , son [l . ~npici~oteNciir;1ii1 CONCLUSIONration adpiN ithrio~ picic atrick) marl and, passic 26c- 1992a ncwrk03-10 /I i. 16219 43-S...Iittmmnc pa\\mi ic nmm 1idtih lhi\\\\ .inI thcthck i liit thc 10tlkmdcd fayc I IN! RODI (lION’ face int tile co re material (it thcQ , ank \\\\ich plat c

  11. Proceedings of the International Conference (7th) on Machine Learning Held in Austin, Texas on 21-23 June 1990

    DTIC Science & Technology

    1990-06-23

    Lebbe, J. Nicolas, P.Peter, R. Vignes : Conceptual clustering in biology applications and perspectives. In Data Analysis, Learning symbolic and numeric...never overgeneralize a positive example. E2r E R n Sol . A class of learning problemsP will be This is a strong assumption, but it does not requiresaid...of the problem space. Our sol - The graph suggests that it is necessary to learn to ution to this problem requires that we derive a number bae th pole

  12. International Symposium on Air Breathing Engines, 7th, Beijing, People's Republic of China, September 2-6, 1985, Proceedings

    SciTech Connect

    Wu, C.H.; Bubb, J.E.

    1985-01-01

    The symposium presents general topics on nozzle and external flows; gas turbine combustor developments; inlets; mechanical aspects; ramjets; controls, diagnostics, and instrumentation; turbomachinery; combustion stability and modeling; and propulsin systems and test facilities. Other topics include inviscid flow in turbomachinery, operations and monitoring, fuel injection, viscous effects in turbomachinery, unsteady effects in turbomachinery, and combustor performance correlations. Papers are presented on aero gas turbine engines for commercial application, combustion research for gas turbine engines, numerical simulation of self-excited oscillations in a ramjet inlet-diffuser flow, some recent advances in the instrumentation of airbreathing engines, and numerical modeling of afterburner combustion. In addition, consideration is given to procedures for trending aircraft gas turbine engine performance, simultaneous measurement of velocities and particle sizes for injection systems and ramjet combustors, and energy losses of equilibrium three-dimensional boundary layer.

  13. Proceedings of the International Pyrotechnics Seminar (7th) Held at Vail, Colorado, 14-18 July 1980. Volume 1

    DTIC Science & Technology

    1980-07-18

    A filmless neutron gauging technique with californium -252 as the neutron source was utilized to provide an automated MDF gauge which continuously...interpretation of the inspection results. The system is configured for maximum inspection sensitivity. Californium -252 is utilized as the neutron...scattering can provide important information for certain samples. A commonly used and available isotopic source of neutrons is californium -252. IRT’s portable

  14. UV-LED-based charge control for LISA

    NASA Astrophysics Data System (ADS)

    Olatunde, Taiwo; Shelley, Ryan; Chilton, Andrew; Ciani, Giacomo; Mueller, Guido; Conklin, John

    2014-03-01

    The test masses inside the LISA gravitational reference sensors (GRS) must maintain almost pure geodesic motion for gravitational waves to be successfully detected. The residual accelerations have to stay below 3fm/s2/rtHz at all frequencies between 0.1 and 3 mHz. One of the well known noise sources is associated with the charges on the test masses which couple to stray electrical potentials and external electro-magnetic fields. The LISA pathfinder (LPF) will use Hg-discharge lamps emitting mostly around 253 nm to discharge the test masses via photoemission in its 2015/16 flight. A future LISA mission launched around 2030 will likely replace the lamps with newer UV-LEDs. UV-LEDs have a lower mass, a better power efficiency, and are smaller than their Hg counterparts. Furthermore, the latest generation produces light at 240 nm, with energy well above the work function of pure gold. I will describe a preliminary design for effective charge control through photoelectric effect by using these LEDs. The effectiveness of this method is verified by taking Quantum Efficiency (QE) measurements which relate the number of electrons emitted to the number of photons incident on the Au test mass surface. This presentation addresses our initial results and future plans which includes implementation and testing in the UF torsion pendulum and space-qualification in a small satellite mission which will launch in the summer of 2014, through a collaboration with Stanford, KACST, and NASA Ames Research Center.

  15. Laser frequency stabilization by dual arm locking for LISA

    SciTech Connect

    Sutton, Andrew; Shaddock, Daniel A.

    2008-10-15

    The Laser Interferometer Space Antenna (LISA) will be the first dedicated space based gravitational wave detector. LISA will consist of a triangular formation of spacecraft, forming an interferometer with 5x10{sup 6} km long arms. Annual length variations of the interferometer arms prevent exact laser frequency noise cancellation. Despite prestabilization to an optical cavity the expected frequency noise is many orders of magnitude larger than the required levels. Arm locking is a feedback control method that will further stabilize the laser frequency by referencing it to the 5x10{sup 6} km arms. Although the original arm locking scheme produced a substantial noise reduction, the technique suffered from slowly decaying start-up transients and excess noise at harmonic frequencies of the inverse round-trip time. Dual arm locking, presented here, improves on the original scheme by combining information from two interferometer arms for feedback control. Compared to conventional arm locking, dual arm locking exhibits significantly reduced start-up transients, no noise amplification at frequencies within the LISA signal band, and more than 50 fold improvement in noise suppression at low frequencies. In this article we present a detailed analysis of the dual arm locking control system and present simulation results showing a noise reduction of 10 000 at a frequency of 10 mHz.

  16. Computer Studies Of The Isleworth And Louvre Mona Lisas

    NASA Astrophysics Data System (ADS)

    Asmus, John F.

    1989-07-01

    One of the most pervasive problems in the scholarship of classical paintings is that of authenticity. Traditionally, the attribution of a work of art rests on the subjective opinion of an art historian bolstered by scientific data pertaining to the types and possibly the ages of the materials of the artwork. To expand the range of technical information that may be applied to the painting authentication problem, the methods of computer image processing (IP) have been employed to compare the techniques in two paintings. One is the Mona Lisa del Gioconda by Leonardo da Vinci. The other is known as the Isleworth Mona Lisa and has also been attributed to Leonardo by a few scholars. Computer IP was used to compare statistical and geometrical features of the two paintings. It emerged that the Isleworth work is not a copy of the Louvre painting but does have numerous similarities in composition and execution. These findings lend support to the theory that the Louvre Mona Lisa may be a portrait of Costanza by Leonardo that had been thought lost.

  17. Heterodyne Stabilization for the Laser Interferometer Space Antenna (LISA)

    NASA Astrophysics Data System (ADS)

    Eichholz, Johannes; Hochman, Steven; Preston, Alix; Mueller, Guido

    2010-10-01

    LISA is a joint NASA/ESA space mission to detect gravitational waves from 0.1 mHz to 1 Hz generated e.g. by super-massive black hole mergers. Three spacecraft move in a triangular constellation on a heliocentric orbit. Their distances are monitored interferometrically with laser links. LISA detects fluctuations of the 5 million km arm lengths on a picometer scale. The requirement for the frequency stability of the lasers is 141 Hz/μHz. I will present a new stabilization scheme based on heterodyne interferometry. It requires less components than the currently envisioned Pound Drever Hall technique and can easily be integrated into LISA's interferometry measurement system. The two lasers of each spacecraft are injected into the same optical cavity. Near resonance, the phase of the reflected light is sensitive to frequency fluctuations. The second, off-resonant beam can be used to lock the primary laser to the cavity resonance. I will discuss this technique and present experimental results. This work is supported by NASA Contract #00078244 and NASA Grant NNX08AG75G.

  18. LISA Framework for Enhancing Gravitational Wave Signal Extraction Techniques

    NASA Technical Reports Server (NTRS)

    Thompson, David E.; Thirumalainambi, Rajkumar

    2006-01-01

    This paper describes the development of a Framework for benchmarking and comparing signal-extraction and noise-interference-removal methods that are applicable to interferometric Gravitational Wave detector systems. The primary use is towards comparing signal and noise extraction techniques at LISA frequencies from multiple (possibly confused) ,gravitational wave sources. The Framework includes extensive hybrid learning/classification algorithms, as well as post-processing regularization methods, and is based on a unique plug-and-play (component) architecture. Published methods for signal extraction and interference removal at LISA Frequencies are being encoded, as well as multiple source noise models, so that the stiffness of GW Sensitivity Space can be explored under each combination of methods. Furthermore, synthetic datasets and source models can be created and imported into the Framework, and specific degraded numerical experiments can be run to test the flexibility of the analysis methods. The Framework also supports use of full current LISA Testbeds, Synthetic data systems, and Simulators already in existence through plug-ins and wrappers, thus preserving those legacy codes and systems in tact. Because of the component-based architecture, all selected procedures can be registered or de-registered at run-time, and are completely reusable, reconfigurable, and modular.

  19. Characterization of the LISA Pathfinder Drag Reduction System

    NASA Astrophysics Data System (ADS)

    Slutsky, Jacob; LISA Pathfinder Team

    2015-04-01

    The LISA Pathfinder mission will be launched this year by ESA, and so it is urgent to simulate and characterize key experiments to optimize and validate the Gravitational Reference Sensor (GRS) performance. Success of this technology directly applies to any future LISA-like mission. Pathfinder is comprised of both European and NASA payloads, the LISA Technology Package (LTP) and Space Technology 7 (ST-7), respectively. ST-7 includes a Colloid Micro-Newton Thruster (CMNT) system, to maneuver the spacecraft with low noise, and a control system for spacecraft and test mass actuation. European partners have developed the LTP Data Analysis (LTPDA) Matlab suite, including state-space simulations of the full mission to create mock data, analysis pipelines constructed to reduce this and eventual actual data. We have adapted this infrastructure to reflect CMNT physics and control design where they differ from LTP. We analyze the residual GRS acceleration noise, paying particular attention to ST-7 specific CMNT noise characterization experiments and the performance differentials between using the inertial and interferometric sensing systems of Pathfinder in and out of loop. I will discuss our current results analyzing simulated ST-7 experimental runs and our future plans.

  20. LISA Pathfinder: First steps to observing gravitational waves from space

    NASA Astrophysics Data System (ADS)

    McNamara, Paul; LISA Pathfinder Collaboration

    2017-01-01

    With the first direct detection of gravitational waves a little over a year ago, the gravitational window to the Universe has been opened. The gravitational wave spectrum spans many orders of magnitude in frequency, with several of the most interesting astronomical sources emitting gravitational waves at frequencies only observable from space The European Space Agency (ESA) has been active in the field of space-borne gravitational wave detection for many years, and in 2013 selected the Gravitational Universe as the science theme for the third large class mission in the Cosmic Vision science programme. In addition, ESA took the step of developing the LISA Pathfinder mission to demonstrate the critical technologies required for a future mission. The goal of the LISA Pathfinder mission is to place a test body in free fall such that any external forces (acceleration) are reduced to levels lower than those expected from the passage of a gravitational wave LISA Pathfinder was launched on the 3rd December 2015 from the European Spaceport in Kourou, French Guiana. After a series of 6 apogee raising manoeuvres, the satellite left earth orbit, and travelled to its final science orbit around the first Sun-Earth Lagrange point (L1). Following a relatively short commissioning phase, science operations began on 1st March 2016. In the following 3 months over 100 experiments and over 1500hours of noise measurements have been performed, demonstrating that the observation of gravitational waves from space can be realised.

  1. Frequency-Tunable Pre-stabilized lasers for LISA via Stabilized Lasers for LISA via Sideband Locking

    NASA Technical Reports Server (NTRS)

    Livas, Jeffrey; Thorpe, James Ira; Numata, K.

    2008-01-01

    This viewgraph presentation discusses a major potential source of noise for the Laser Interferometer Space Antenna (LISA) that is the laser frequency noise and the proposed mechanism to suppress the unstabilized frequency fluctuations. These fluctuations must be suppresed by about 12 orders of magnitude to achieve a stability that is sufficient for the detection of gravitational waves. This presentation reviews present a modification to the traditional cavity locking technique that allows the laser to be locked to a cavity resonance with an adjustable frequency offset. This presentation also discusses measurements of the system stability, demonstrating that the pre-stabilization level satisfies LISA requirements and a demonstration of a phase-lock loop which utilizes the tunable sideband locking technique as a pre-stabilization stage.

  2. Lifelong Learning Research Conference Proceedings (7th, College Park, Maryland, February 21-22, 1985).

    ERIC Educational Resources Information Center

    Rivera, William M., Comp.; Walker, Sharon M., Comp.

    The 48 papers in this proceedings focus on aspects of non-formal adult education including international comparative adult education. The papers are: "Lifelong Learning in Perspective" (Knox); "Women in their Thirties: The In-Between Generation" (Caffarella, Freeman); "Development in Women: An Analysis of the…

  3. Laser Stabilization and Material Studies for the Laser Interferometer Space Antenna (LISA)

    NASA Astrophysics Data System (ADS)

    Cordes, Amanda; Mueller, G.; Tanner, D. B.; Arsenovic, P.; Livas, J.; Preston, A.; Sanjuan, J.; Reza, S. A.; Mitryk, S.; Eichholz, J.; Spector, A.; Donelan, D.; Spannagel, R.; Korytov, D.

    2011-05-01

    The Laser Interferometer Space Antenna (LISA) is a joint NASA/ESA project designed to detect gravitational waves. The University of Florida (UF) LISA laboratory is currently implementing and testing much of the instrumentation of the LISA interferometer measurement system to ensure the success of the upcoming LISA mission. LISA will consist of three spacecraft (SC) orbiting the sun in an equilateral triangular formation with an arm length of 5 Gm. Each SC will house two free floating proof-masses, two laser interferometer benches and two telescopes to transmit the laser light between SC. The constellation will trail the earth by 20° and be tilted by 60° with respect to the ecliptic. LISA is designed to detect low frequency gravitational waves (GWs) in the frequency band of .1mHz to 1 Hz with optimal strain sensitivity of 10^-21/sqrt(Hz) at 3 mHz corresponding to sources such as galactic binaries and black hole mergers. The dimensional stability of all optical paths within each interferometer arm is imperative for the success of LISA. Changes larger than a pm/sqrt(Hz) in the distance between optical components in the interferometer would limit the sensitivity of LISA. The UF LISA lab is testing materials with low thermal expansion coefficients which could be used as spacer materials for the telescopes or as the base material for the optical benches. Together with the LISA group at Goddard Space Flight Center we currently also test the dimensional stability of a silicon carbide telescope structure for LISA. The most demanding requirement on material stability is the requirement for the optical reference cavity which is used as the frequency reference for the lasers. We currently test different sensing schemes for the laser frequency stabilization system of LISA and will also report about these experiments. This work is supported by NASA Contract #00078244 and NASA Grant NNX08AG75G.

  4. Solar And Cosmic Ray Physics And The Space Environment: Studies For And With LISA

    SciTech Connect

    Shaul, D. N. A.; Araujo, H.; Quenby, J. J.; Sumner, T.; Wass, P.; Aplin, K. L.; Bingham, R.; Hapgood, M.; Kellet, B.; Young, P.; Blake, J. B.; Mulligan, T.; Branduardi-Raymont, G.; Fazakerley, A.; Matthews, S.; Buchman, S.; Finn, L. S.; Roming, P.; Fletcher, L.; Glover, A.

    2006-11-29

    With data analysis preparations for LISA underway, there has been renewed interest in studying solar, cosmic ray and environmental physics for, and using LISA. The motivation for these studies is two fold. The primary incentive is to predict and consequently minimize the impact of disturbances associated with these factors, to maximize LISA's gravitational wave scientific yield. The second stimulus is the unique opportunity that is afforded by LISA's long-baseline 3-spacecraft configuration for studies of solar, cosmic ray and environmental physics. Here we present an overview of recent progress in these studies.

  5. Simulating Gravitational Radiation from Binary Black Holes Mergers as LISA Sources

    NASA Technical Reports Server (NTRS)

    Baker, John

    2005-01-01

    A viewgraph presentation on the simulation of gravitational waves from Binary Massive Black Holes with LISA observations is shown. The topics include: 1) Massive Black Holes (MBHs); 2) MBH Binaries; 3) Gravitational Wavws from MBH Binaries; 4) Observing with LISA; 5) How LISA sees MBH binary mergers; 6) MBH binary inspirals to LISA; 7) Numerical Relativity Simulations; 8) Numerical Relativity Challenges; 9) Recent Successes; 10) Goddard Team; 11) Binary Black Hole Simulations at Goddard; 12) Goddard Recent Advances; 13) Baker, et al.:GSFC; 13) Starting Farther Out; 14) Comparing Initial Separation; 15) Now with AMR; and 16) Conclusion.

  6. Impact of LISA's Low Frequency Sensitivity on Observations of Massive Black Hole Mergers

    NASA Technical Reports Server (NTRS)

    Baker, J.; Centrella, J.

    2005-01-01

    LISA will be able to detect gravitational waves from inspiralling massive black hole (MBH) binaries out to redshifts z > 10. If the binary masses and luminosity distances can be extracted from the Laser Interferometer Space Antenna (LISA) data stream, this information can be used to reveal the merger history of MBH binaries and their host galaxies in the evolving universe. Since this parameter extraction generally requires that LISA observe the inspiral for a significant fraction of its yearly orbit, carrying out this program requires adequate sensitivity at low frequencies, f < 10(exp -4) Hz. Using several candidate low frequency sensitivities, we examine LISA's potential for characterizing MBH binary coalescences at redshifts z > 1.

  7. A Giant Leap Towards a Space-based Gravitational-Wave Observatory: LISA Pathfinder, the LISA Test Package, and ST7-DRS

    NASA Astrophysics Data System (ADS)

    Thorpe, James; McNamara, Paul; Ziemer, John; LPF Team, LTP Team, ST7-DRS Team

    2015-01-01

    The science case for a space-based gravitational wave instrument observing in the milliHertz band covers a wide area of topics in astrophysics and fundamental physics including galaxy formation and evolution, black hole growth, compact object demographics, gravitational physics, and cosmology. This strong science case is largely responsible for the high rankings received by the Laser Interferometer Space Antenna (LISA) mission in major reviews in both the US and Europe. A key element of the development of LISA is the LISA Pathfinder (LPF) technology demonstrator mission, which will launch in the coming year. Led by ESA and a consortium of European national agencies and with a minority contribution from NASA, LPF will demonstrate several key technologies for the LISA concept. LPF includes two scientific payloads: the European LISA Technology Package (LTP) and the NASA-provided ST7-DRS. The mission will place two test masses in drag-free flight and measure the relative acceleration between them. This measurement will validate a number of technologies that are critical to LISA-like gravitational wave instruments including sensing and control of the test masses, drag-free control laws, micro-Newton thrusters, and picometer-level laser metrology. We will present an overview of the LISA Pathfinder mission, the LTP and ST7-DRS payloads, and their expected impact on the larger effort to realize a space-based gravitational wave observatory.

  8. Laser Interferometer Space Antenna (LISA) Far Field Phase Patterns

    NASA Technical Reports Server (NTRS)

    Waluschka, Eugene; Obenschain, Arthur F. (Technical Monitor)

    2000-01-01

    The Laser Interferometer Space Antenna (LISA) consists of three spacecraft in orbit about the sun. The orbits are chosen such that the three spacecraft are always at (roughly) the vertices of a equilateral triangle with 5 million kilometer leg lengths. Even though the distances between the three spacecraft are 5 million kilometers, the expected phase shifts between any two beams, due to a gravitational wave, only correspond to a distance change of about 10 pico meters, which is about 10(exp -5) waves for a laser wavelength of 1064 nm. To obtain the best signal-to-noise ratio, noise sources such as changes in the apparent distances due to pointing jitter must be controlled carefully. This is the main reason for determining the far-field phase patterns of a LISA type telescope. Because of torque on the LISA spacecraft and other disturbances, continuous adjustments to the pointing of the telescopes are required. These pointing adjustments will be a "jitter" source. If the transmitted wave is perfectly spherical then rotations (Jitter) about its geometric center will not produce any effect at the receiving spacecraft. However, if the outgoing wave is not perfectly spherical, then pointing jitter will produce a phase variation at the receiving spacecraft. The following sections describe the "brute force" computational approach used to determine the scalar wave front as a function of exit pupil (Zernike) aberrations and to show the results (mostly graphically) of the computations. This approach is straightforward and produces believable phase variations to sub-pico meter accuracy over distances on the order of 5 million kilometers. As such this analyzes the far field phase sensitivity to exit pupil aberrations.

  9. Recent LISA studies at the University of Colorado

    NASA Astrophysics Data System (ADS)

    Nickerson, M.; Ames, E.; Bender, P. L.

    2009-03-01

    We report on LISA experimental projects being pursued at JILA. Our focus is on the design and testing of a flight-compatible laser stabilization reference cavity. This is a dual cylinder ULE cavity, designed to provide high thermal and thermo-mechanical isolation in the millihertz frequency regime of interest to LISA. A modification of this hard-mounted design may allow for use in space without the need for clamping during launch. Progress so far consists of initial design, performance estimates, and construction. Simple thermal model calculations on the design indicate a thermal attenuation of 106 at 1 mHz, corresponding to a cavity strain of 3*10-16 /rtHz for a 0.01 K/rtHz stability of the mounting surface. Finite element analysis indicates cavity strain attenuation of 5*107 or better due to thermo-mechanical effects in the surrounding environment, and low sensitivity to vibration along the cavity axis. Setup and testing of two identical cavities and a laser-locking test system is ongoing. Another project was recently concluded, testing the low-frequency stability of commercial voltage references. Voltage reference performance is relevant to the stability of electrically applied forces on the LISA proof masses, and commercial references do not have well characterized noise in the sub-Hz regime. Our measurements confirmed that the best commercial reference was the AD587LN, with a typical noise of 2.1±0.6 ppm/rtHz at 0.1 mHz, in a temperature-stabilized environment of ~10mK/rtHz. This agrees closely with prior work by other groups.

  10. Thermal diagnostics front-end electronics for LISA Pathfinder.

    PubMed

    Sanjuán, J; Lobo, A; Nofrarias, M; Ramos-Castro, J; Riu, P J

    2007-10-01

    Precision temperature measurements are required in the LTP, the LISA technology package, for various diagnostics objectives. In this article, we describe in detail the front-end electronics design and the associated temperature sensors to achieve the LTP requirements: noise equivalent temperature of 10 microK Hz(-12) in the frequency range from 1 to 30 mHz at room temperature. We designed an ac Wheatstone bridge and a subsequent digital demodulation to minimize 1/f noise. We show experimental results where the required sensitivity in the measurement bandwidth is fulfilled.

  11. Laser Interferometer Space Antenna (LISA) Far Field Phase Pattern

    NASA Technical Reports Server (NTRS)

    Waluschka, Eugene

    1999-01-01

    The Laser Interferometry Space Antenna (LISA) for the detection of Gravitational Waves is a very long baseline interferometer that will measure the changes in the distance of a five million kilometer arm to pico meter accuracies. Knowledge of the phase deviations from a spherical wave and what causes these deviations are needed considerations in (as a minimum) the design of the telescope and in determining pointing requirements. Here we present the far field phase deviations from a spherical wave for given Zernike aberrations and obscurations of the exit pupil.

  12. Laser Interferometer Space Antenna (LISA) Far Field Phase Patterns

    NASA Technical Reports Server (NTRS)

    Waluschka, Eugene

    1999-01-01

    The Laser Interferometer Space Antenna (LISA) for the detection of Gravitational Waves is a very long baseline interferometer, which will measure the changes in the distance of a five million kilometer arm to picometer accuracies. Knowledge of the phase deviations from a spherical wave and what causes these deviations are needed considerations in (as a minimum) the design of the telescope and in determining pointing requirements. Here we will present the far field phase deviations from a spherical wave for given Zernike aberrations of the exit pupil and discuss how these results affect the choice of a telescope design.

  13. An interview with Alfredo Falcone and Lisa Salvatore: RECOURSE and trifluridine/tipiracil in metastatic colorectal cancer.

    PubMed

    Falcone, Alfredo; Salvatore, Lisa

    2016-09-01

    Professor Alfredo Falcone and Dr Lisa Salvatore speak to Roshaine Gunawardana, Managing Commissioning Editor: Professor Alfredo Falcone is the Director of the Department of Oncology and the Specialization School at the University Hospital of Pisa, Italy. He trained in Pisa and Genoa, Italy, and has held major positions in Italian oncology since 2000. He currently has more than 300 publications, including papers in peer-reviewed international and national journals, book chapters, and more than 600 abstracts of presentations to international and national conferences. The majority of his papers regard clinical and translational research, with a particular focus on metastatic colorectal cancer. Dr Lisa Salvatore is a medical oncologist in the Department of Translational Research and New Technologies in Medicine and Surgery at the University of Pisa. She has been an author on about 40 publications in major peer-reviewed publications and has made numerous presentations in national and international conferences. Her main interest is focused on clinical and translational research in metastatic colorectal cancer.

  14. [Prevalence of smoking habits of Upper Austria students of the 7th and 8th grade and effect of smoking habits of family and peers].

    PubMed

    Zidek, T; Haidinger, G; Zacharasiewicz, A; Waldhör, T; Vutuc, C

    2000-01-01

    The aim of the study was to explore the prevalence of different smoking habits in a population of Austrian pupils, 12 to 15 years old, and the relationship of familial and peer group smoking customs with these habits. In 1997 a population-based survey (International Study of Asthma and Allergies in Childhood, ISAAC) was conducted of all 7th and 8th grade school children of a district of Upper Austria. Information on the smoking habits of the adolescents, the family members, and of the peer as well as smoking habits of the teacher, gender, and age of the children was collected. The overall-prevalence of having ever smoked in this population is 57.8%. The percentage of eversmokers among the 12-year-olds is 50%. This amount increases to 63.8% among the 14- to 15-year-olds. The odds ratios for smoking daily is highest among those whose best friend smokes (OR: 70.63, CI: 9.19, 542.40). The risk of daily smoking increases also if the siblings of the juvenile (OR: 4.71, CI: 1.15, 19.35) or the mother (OR: 4.95, CI: 1.67, 14.70) smoke. If the father smokes the risk to smoke monthly is increased (OR: 2.09, CI: 1.28, 3.40). These results point to the fact that smoking prevention programes should take into account the influence of peers and family of the adolescents.

  15. Multi-MW K-Band 7th Harmonic Multiplier for High-Gradient Accelerator R&D

    SciTech Connect

    Solyak, N.A.; Yakovlev, V.P.; Hirschfield, J.L.; Kazakevich, G.M.; LaPointe, M.A.; /Yale U.

    2009-05-01

    A preliminary design and current status are presented for a two-cavity 7th harmonic multiplier, intended as a high-power RF source for use in experiments aimed at developing high-gradient structures for a future collider. The harmonic multiplier is to produce power in K-band using as its RF driver an XK-5 S-band klystron (2.856 GHz). The multiplier is to be built with a TE{sub 111} rotating mode input cavity and interchangeable output cavities, a principal example being a TE{sub 711} rotating mode cavity running at 20 GHz. The design that is described uses a 250 kV, 20 A injected laminar electron beam. With 8.5 MW of S-band drive power, 4.4 MW of 20-GHz output power is predicted. The design uses a gun, magnetic coils, and beam collector from an existing waveguide 7th harmonic multiplier. The gun has been re-conditioned and the desired operating parameters have been achieved.

  16. Observing Merging Massive Black Hole Binaries with LISA

    NASA Technical Reports Server (NTRS)

    Thorpe, J.; McWillimas, S.; Baker, J.; Arnaud, K.

    2009-01-01

    The Laser Interferometer Space Antenna (LISA) is expected to detect gravitational radiation from the inspiral and merger of massive black hole binaries at high redshifts with large signal-to-noise ratios (SNRs). These high-SNR observations will make it possible to extract physical parameters such as hole masses and spins, luminosity distance, and sky position from the observed waveforms. LISA'S effectiveness as a tool for astrophysics will be influenced by the precision with which these parameters can be measured. In addition, the practicality of coordinated observations with other instruments will be affected by the temporal evolution of parameter errors such as sky position. We present estimates of parameter errors for the special case of non-spinning black holes. Our focus is on the contribution of the late inspiral and merger portions of the waveform, a regime which typically dominates the SNR but has not been extensively studied due to the historic lack of a precise description of the waveform. Advances in numerical relativity have recently made such studies possible. Initial results suggest that the portion of the waveform beyond the Schwarzchild inner-most stable circular orbit can reduce parameter uncertainties by up to a factor of two.

  17. Weak-light Phase-locking for LISA

    NASA Technical Reports Server (NTRS)

    McNamara, Paul W.

    2004-01-01

    The long armlengths of the LISA interferometer, and the finite aperture of the telescope, leads to an optical power attenuation of approximately equal to 10(exp -10) of the transmitted to received light. Simple reflection at the end of the arm is therefore not an optimum interferometric design. Instead, a local laser is offset phase-locked to the weak incoming beam, transferring the phase information of the incoming to the outgoing light. This paper reports on an experiment to characterize a weak light phase-locking scheme suitable for LISA in which a diode-pumped, Nd:YAG, non-planar ring oscillator (NPRO) is offset phase-locked to a low power (13pW) frequency stabilised master NPRO. Preliminary results of the relative phase noise of the slave laser shows shot noise limited performance above 0.4 Hz. Excess noise is observed at lower frequencies, most probably due to thermal effects in the optical arrangement and phase sensing electronics.

  18. Characterization of the LISA Pathfinder Drag Reduction System

    NASA Astrophysics Data System (ADS)

    Slutsky, Jacob; LISA Pathfinder Team

    2016-03-01

    The LISA Pathfinder (LPF) mission launched in December 2015 with operations beginning March 2016. LPF is a technology demonstration mission built to prove and fully characterize the performance of the use of drag free test masses as Gravitational Reference Sensors (GRS) for future space based gravitational-wave observatories. As a joint ESA-NASA mission, LPF is comprised of both European and NASA payloads, the LISA Technology Package (LTP) and Disturbance Reduction System (DRS), respectively. DRS includes Colloid Micro-Newton Thruster (CMNT) systems, to precisely maneuver the spacecraft without disturbing the GRS, and a control system that directs spacecraft and test mass actuation. In order to fully characterize DRS/CMNT performance, we have developed a series of experiments, to take place during DRS operations beginning later this year. We have built analysis pipelines, validated on simulated data, to rapidly process experimental data and to identify any performance issues as they occur. European partners have developed the LTP Data Analysis (LTPDA) Matlab extension, and we have adapted and expanded this to DRS missions as the basis of our analysis pipelines. I will discuss the anticipated DRS performance and measurement accuracy, illustrated on simulated data.

  19. Using LISA to Learn How Pairs of Black Holes Formed

    NASA Astrophysics Data System (ADS)

    Kohler, Susanna

    2016-11-01

    Artists impression of the European Space Agencys Laser Interferometer Space Antenna, currently planned for a 2034 launch. [NASA]How are black-hole binaries built? Observations of gravitational waves from these systems made using the European Space Agencys upcoming mission, the Laser Interferometer Space Antenna (LISA) may be able to reveal their origins.Formation ChannelsThere are two primary placeswhere stellar-mass black-hole binaries are thought to form:In isolation in the galactic field, as the components of a stellar binary independently evolve into black holes but remain bound to each other.In dense stellar environments like globular clusters, where the high density of already-formed black holes can cause a pair to dynamically interact and form a binary before being ejected from the cluster.Can we differentiate between these origins based on future detections of gravitational waves from black-hole binaries? A team of scientists led by Katelyn Breivik (CIERA, Northwestern University) thinks that we can!The gravitational-wave spectrum and how we detect it (click for a closer look!). While ground-based interferometers like LIGO detect black-hole binaries in the final moments before merger, LISAs lower frequency band will allow it to detect binaries earlier in their inspiral. [NASA Goddard SFC]Differentiation by EccentricityBreivik and collaborators believe that the key clue is the binarys eccentricity. Gravitational-wave emission will eventually circularize all black-hole binaries during their inspiral. But in the first formation scenario, binary evolution processes like tidal circularization and mass transfer will reduce the binarys eccentricity early on whereas in the second scenario, the binaries that form in globular clusters may retain eccentricity in their orbits long enough that we can detect it.Ground-based interferometers wont be up to this task; by the time the binary orbits shrink enough to evolve into the LIGO frequency band, the orbits wont have

  20. Development of a Thrust Stand to Meet LISA Mission Requirements

    NASA Technical Reports Server (NTRS)

    Willis, William D., III; Zakrzwski, Charles M.; Merkowitz, Stephen M.

    2002-01-01

    A thrust stand has been built to measure the force-noise produced by electrostatic micro-Newton (muN) thrusters. The LISA mission's Disturbance Reduction System (DRS) requires thrusters that are capable of producing continuous thrust levels between 1-100 muN with a resolution of 0.1 muN. The stationary force-noise produced by these thrusters must not exceed 0.1 muN/dHz in the measurement bandwidth 10(exp -4) to 1 Hz. The LISA Thrust Stand (LTS) is a torsion-balance type thrust stand designed to meet the following requirements: stationary force-noise measurements from l0( -4) to 1 Hz with 0.1 muN/dHz sensitivity, absolute thrust measurements from 1-100 muN with better than 0.1 muN resolution, and dynamic thruster response from to 10 Hz. The LTS employs a unique vertical configuration, autocollimator for angular position measurements, and electrostatic actuators that are used for dynamic pendulum control and null-mode measurements. Force-noise levels are measured indirectly by characterizing the thrust stand as a spring-mass system. The LTS was initially designed to test the indium FEEP thruster developed by the Austrian Research Center in Seibersdorf (ARCS), but can be modified for testing other thrusters of this type.

  1. Preparing for LISA in the post-detection era

    NASA Astrophysics Data System (ADS)

    Conklin, John

    2017-01-01

    In 2016 we saw the first direct detections of gravitational waves by Advanced LIGO and the positive results from LISA Pathfinder. In this context, NASA has decided to partner with the ESA on their L3 gravitational wave observatory, whose science goals are outlined in the white paper, The Gravitational Universe. The current launch date for L3 is 2034, but with the success of Pathfinder and the increased scientific interest in gravitational waves caused by LIGO, ESA and its member states are exploring ways to move up the launch date. In the U.S., the National Academy's Astronomy Midterm Assessment has recommended that NASA restore support for a gravitational wave mission in this decade with the goal of realizing the full scientific capability of the mission envisioned in the 2020 decadal. NASA has appointed the L3 Study Team, charged with providing analysis of potential U.S. contributions to the European-led L3 mission and preparing for the next decadal survey. The LISA mission concept, proposed for L3, will improve our understanding of the formation and growth of massive black holes, create a census of compact binary systems in the Milky Way, test general relativity in extreme conditions, provide predictions of black hole binary mergers in the LIGO frequency band, and enable searches for new physics.

  2. Disentangling the magnetic force noise contribution in LISA Pathfinder

    NASA Astrophysics Data System (ADS)

    Armano, M.; Audley, H.; Auger, G.; Baird, J.; Binetruy, P.; Born, M.; Bortoluzzi, D.; Brandt, N.; Bursi, A.; Caleno, M.; Cavalleri, A.; Cesarini, A.; Cruise, M.; Danzmann, K.; Diepholz, I.; Dolesi, R.; Dunbar, N.; Ferraioli, L.; Ferroni, V.; Fitzsimons, E.; Freschi, M.; Gallegos, J.; García Marirrodriga, C.; Gerndt, R.; Gesa, L. I.; Gibert, F.; Giardini, D.; Giusteri, R.; Grimani, C.; Harrison, I.; Heinzel, G.; Hewitson, M.; Hollington, D.; Hueller, M.; Huesler, J.; Inchauspé, H.; Jennrich, O.; Jetzer, P.; Johlander, B.; Karnesis, N.; Kaune, B.; Korsakova, N.; Killow, C.; Lloro, I.; Maarschalkerweerd, R.; Madden, S.; Mance, D.; Martín, V.; Martin-Porqueras, F.; Mateos, I.; McNamara, P.; Mendes, J.; Mendes, L.; Moroni, A.; Nofrarias, M.; Paczkowski, S.; Perreur-Lloyd, M.; Petiteau, A.; Pivato, P.; Plagnol, E.; Prat, P.; Ragnit, U.; Ramos-Castro, J.; Reiche, J.; Romera Perez, J. A.; Robertson, D.; Rozemeijer, H.; Russano, G.; Sarra, P.; Schleicher, A.; Slutsky, J.; Sopuerta, C. F.; Sumner, T.; Texier, D.; Thorpe, J.; Trenkel, C.; Tu, H. B.; Vitale, S.; Wanner, G.; Ward, H.; Waschke, S.; Wass, P.; Wealthy, D.; Wen, S.; Weber, W.; Wittchen, A.; Zanoni, C.; Ziegler, T.; Zweifel, P.

    2015-05-01

    Magnetically-induced forces on the inertial masses on-board LISA Pathfinder are expected to be one of the dominant contributions to the mission noise budget, accounting for up to 40%. The origin of this disturbance is the coupling of the residual magnetization and susceptibility of the test masses with the environmental magnetic field. In order to fully understand this important part of the noise model, a set of coils and magnetometers are integrated as a part of the diagnostics subsystem. During operations a sequence of magnetic excitations will be applied to precisely determine the coupling of the magnetic environment to the test mass displacement using the on-board magnetometers. Since no direct measurement of the magnetic field in the test mass position will be available, an extrapolation of the magnetic measurements to the test mass position will be carried out as a part of the data analysis activities. In this paper we show the first results on the magnetic experiments during an end- to-end LISA Pathfinder simulation, and we describe the methods under development to map the magnetic field on-board.

  3. ISSOL Meeting, 7th, Barcelona, Spain, July 4-9, 1993. [Abstracts only

    NASA Technical Reports Server (NTRS)

    Ferris, James P. (Editor)

    1994-01-01

    The journal issue consists of abstracts presented at the International Society for the Study of the Origins of Life (ISSOL) conference. Topics include research on biological and chemical evolution including prebiotic evolution: cosmic and terrestrial; mechanisms of abiogenesis including synthesis and reactions of biomonomers; and analysis of cometary matter and its possible relationship to organic compounds on Earth. Theories and research on origins of ribonucleic acids (RNA), deoxyribonucleic acid (DNA), and other amino acids and complex proteins including their autocatalysis, replication, and translation are presented. Abiotic synthesis of biopolymers, mechanisms of the Genetic Code, precellular membrane systems and energetics are considered. Earth planetary evolution including early microfossils and geochemical conditions and simulations to study these conditions are discussed. The role of chirality in precellular evolution and the taxonomy and phylogeny of very simple organisms are reported. Past and future explorations in exobiology and space research directed toward study of the origins of life and solar system evolution are described.

  4. 7th BOC Priestley Conference. Final technical report, May 1, 1994--April 30, 1995

    SciTech Connect

    1995-07-01

    The 1994 BOC Priestly Conference was held at Bucknell University in Lewisburg, PA, from June 24 through June 27, 1994. This conference, managed by the American Chemical Society (ACS), was a joint celebration with the Royal Society of Chemistry (RSC) commemorating Joseph Priestley`s arrival in the US and his discovery of oxygen. There were 120 attendees. The basic theme of the conference was Oxidants and Oxidation in the Earth`s Atmosphere, with a keynote lecture on the history of ozone. A distinguished group of US and international atmospheric chemists addressed the issues dominating current research and policy agendas. Topics crucial to the atmospheric chemistry of global change and local and regional air pollution were discussed. The program for the conference included four technical sessions on the following topics: Oxidative fate of atmospheric pollutants; Photochemical smog and ozone; Stratospheric ozone; and, Global tropospheric ozone.

  5. Industry Initiated Core Safety Attributes for Human Spaceflight for the 7th IAASS Conference

    NASA Technical Reports Server (NTRS)

    Mango, Edward J.

    2014-01-01

    Now that the NASA Commercial Crew Program (CCP) is beginning its full certification contract for crew transportation to the International Space Station (ISS), is it time for industry to embrace a minimum set of core safety attributes? Those attributes can then be evolved into an industry-led set of basic safety standards and requirements. After 50 years of human space travel sponsored by governments, there are two basic conditions that now exist within the international space industry. The first, there is enough of a space-faring history to encourage the space industry to design, develop and operate human spaceflight systems without government contracts for anything other than services. Second, industry is capable of defining and enforcing a set of industry-based safety attributes and standards for human spaceflight to low-Earth orbit (LEO). This paper will explore both of these basic conditions with a focus on the safety attributes and standards. In the United States, the Federal Aviation Administration (FAA) is now starting to dialogue with industry about the basic safety principles and attributes needed for potential future regulatory oversight. This process is not yet formalized and will take a number of years once approval is given to move forward. Therefore, throughout the next few years, it is an excellent time and opportunity for industry to collaborate together and develop the core set of attributes and standards. As industry engages and embraces a common set of safety attributes, then government agencies, like the FAA and NASA can use that industry-based product to strengthen their efforts on a safe commercial spaceflight foundation for the future. As the commercial space industry takes the lead role in establishing core safety attributes, and then enforcing those attributes, the entire planet can move away from governmental control of design and development and let industry expand safe and successful space operations in LEO. At that point the

  6. eLISA eccentricity measurements as tracers of binary black hole formation

    NASA Astrophysics Data System (ADS)

    Nishizawa, Atsushi; Berti, Emanuele; Klein, Antoine; Sesana, Alberto

    2016-09-01

    Up to hundreds of black hole binaries individually resolvable by eLISA will coalesce in the Advanced LIGO and Virgo band within 10 yr, allowing for multiband gravitational wave observations. Binaries formed via dynamical interactions in dense star clusters are expected to have eccentricities e0˜10-3-10-1 at the frequencies f0=10-2 Hz where eLISA is most sensitive, while binaries formed in the field should have negligible eccentricity in both frequency bands. We estimate that eLISA should always be able to detect a nonzero e0 whenever e0≳10-2; if e0˜10-3, eLISA should detect nonzero eccentricity for a fraction ˜90 % (˜25 %) of binaries when the observation time is Tobs=5 (2) yr, respectively. Therefore eLISA observations of black hole binaries have the potential to distinguish between field and cluster formation scenarios.

  7. A compositional study of a museum jewellery collection (7th-1st BC) by means of a portable XRF spectrometer

    NASA Astrophysics Data System (ADS)

    Karydas, A. G.; Kotzamani, D.; Bernard, R.; Barrandon, J. N.; Zarkadas, Ch.

    2004-11-01

    Within the framework of the project "Jewelmed" (ICA3-1999-10020), the chemical composition of 34 gold and four silver jewels was examined. These jewels belong to the Benaki museum's collection in Athens, Greece and are dating from the 7th to the 1st century BC. The compositional analysis of the jewels was performed by means of a "home-made" portable X-ray fluorescence (XRF) spectrometer. The XRF results have shown that the gold jewels can be categorized in two groups, which include artifacts made by native and by high purity gold, respectively. For the silver jewels the results have provided interesting information regarding the manufacturing technology, the authenticity of the jewels and the raw materials used. The potential and the limitations of the XRF technique, applied in the chemical analysis of archaeological metal artifacts, are also discussed.

  8. UV-induced Oxygen Removal for Photostable High Efficiency PTB7-Th: PC71BM Photovoltaic Cells.

    PubMed

    Liu, Quan; Mantilla-Perez, Paola; Montes Bajo, Miguel; Romero-Gomez, Pablo; Martorell, Jordi

    2016-10-03

    Solution-processed ZnO sol-gel or nanoparticles are widely used as the electron transporting layer (ETL) in optoelectronic devices. However, chemisorbed oxygen on the ZnO layer surface has been shown to be detrimental for the device performance as well as stability. Herein, we demonstrate that a chemisorbed oxygen removal based on a UV illumination of the ZnO surface layer under a nitrogen atmosphere can, simultaneously, improve power conversion efficiency and photostability of PTB7-Th: PC71BM based inverted polymer solar cells. By a systematic study of such UV illumination procedure, we obtained optimal conditions where, both, the cell efficiency and stability were improved. We fabricated cells with a power conversion efficiency higher than 9.8%, and with a T80 lifetime larger than 500 hours, corresponding to about a 2.5-fold enhancement relative to non-UV treated ZnO reference devices.

  9. Incorporation of perineural invasion of gastric carcinoma into the 7th edition tumor-node-metastasis staging system.

    PubMed

    Jiang, Nan; Deng, Jing-Yu; Liu, Yong; Ke, Bin; Liu, Hong-Gen; Liang, Han

    2014-09-01

    The aim of this study was to determine the prognostic value of perineural invasion (PNI) in patients with gastric cancer who underwent curative resection. We retrospectively analyzed 518 patients who had undergone curative gastrectomy. Paraffin sections of surgical specimens from all patients were stained with hematoxylin and eosin. PNI was defined when carcinoma cells infiltrated into the perineurium or neural fascicles. Patients with PNI had a significantly larger tumors (≥5.0 cm), lymphatic venous invasion (positive), deeper tumor invasion (T4), more number of lymph node metastases (N3), and higher tumor stage (III). Regarding survival, multivariate analysis showed that PNI emerged as an independent prognostic factor for survival (hazard ratio (HR) = 1.901, P < 0.001). We incorporated the PNI into the 7th edition tumor-node-metastasis (TNM) staging system. Comparing with the 7th edition staging system, the redefinition of TPNI stage had higher -2loglikelihood value (-2loglikelihood = 3,492.259) and lower HR and 95 % confidence interval (CI) (HR = 1.955, 95 % CI = 1.630-2.343); redefinition of NPNI and TNMIIIPNI stage both had lower -2loglikelihood value (-2loglikelihood = 3,306.608; -2loglikelihood = 2,535.151) and higher HR and 95 % CI (HR = 1.879, 95 % CI = 1.720-2.053; HR = 2.268, 95 % CI = 1.900-2.707), which represented the optimum prognostic stratification, together with better homogeneity, discriminatory ability. Our results showed that the frequency of PNI was high in patients with gastric cancer who underwent curative gastrectomy and the proportion of PNI positivity increased with progression and clinical stage of disease. PNI may be useful in detecting patients who had poor prognosis after curative resection in gastric cancer and it should be incorporated into TNM staging.

  10. LISA Pathfinder: A Summary of results to date

    NASA Astrophysics Data System (ADS)

    Thorpe, James; LISA Pathfinder Team; LTP Team; DRS Team

    2017-01-01

    The LISA Pathfinder mission is an ESA-led mission with contributions from several European member states and NASA which has the primary purpose of validating technologies for a future space-based observatory of gravitational waves. Launched on Dec. 3rd, 2015, LPF has been conducting science operations since March 1st, 2016 and is now entering an extended mission phase that is expected to last unitl June 2016. This poster will present an overview of the LPF results, the highlight of which is the exquiste measurement of differential acceleration at the femto-g level and interferometry at the femtometer level. In addition, I will describe auxilliary analyses that have been applied to the LPF data to search for impacts from micrometeorites and interactions with the Solar environment.

  11. Simulation and template generation for LISA Pathfinder Data Analysis

    NASA Astrophysics Data System (ADS)

    Rais, Boutheina; Grynagier, Adrien; Diaz-Aguiló, Marc; Armano, Michele

    The LISA PathFinder (LPF) mission is a technology demonstration mission which aims at testing a number of critical technical challenges that the future LISA (Gravitational wave detection in space) mission will face: LPF can be seen as a complex laboratory experiment in space. It is therefore critical to be able to define which measurements and which actuations will be applied during the scientific part of the mission. The LISA Technology Package (LTP), part of ESA's hardware contribution to LPF, outlines hence the importance of developing an appropriate simulation tool in order to test these strate-gies before launch and to analyse the dynamical behaviour of the system during the mission. The detailed model of the simulation can be used in an off-line mode for further planning: cor-rect estimation of timeline priorities, risk factors, duty cycles, data analysis readiness. The Lisa Technology Package Data Analysis (LTPDA) team has developed an object-oriented MATLAB toolbox for general case of data analysis needs. However, to meet specific needs of LPF mis-sion, a template generation tool has been developed. It provides a recognizable data pattern, avoiding the risk of missing the model during mission's analysis. The aim of the template generator tool is to provide tools to analyse LTP system modeled in State Space Model (SSM). The SSM class, the aim of this poster, includes this tools within the LTPDA toolbox. It can be used to generate the time-domain response for any given actuation and/or noise, the frequency response using bode diagrams and the steady state of the system. It allows the user to project noises on system outputs to get spectra of outputs for given input noises spectra. This class is sufficiently general to be used with a variety of systems once the SSM of the system is provided in the library. Furthermore, one of the main objectives of the data analysis for LPF (the estimation of different parameters of the system), can be achieved by a new

  12. The LISA Pathfinder interferometry—hardware and system testing

    NASA Astrophysics Data System (ADS)

    Audley, H.; Danzmann, K.; García Marín, A.; Heinzel, G.; Monsky, A.; Nofrarias, M.; Steier, F.; Gerardi, D.; Gerndt, R.; Hechenblaikner, G.; Johann, U.; Luetzow-Wentzky, P.; Wand, V.; Antonucci, F.; Armano, M.; Auger, G.; Benedetti, M.; Binetruy, P.; Boatella, C.; Bogenstahl, J.; Bortoluzzi, D.; Bosetti, P.; Caleno, M.; Cavalleri, A.; Cesa, M.; Chmeissani, M.; Ciani, G.; Conchillo, A.; Congedo, G.; Cristofolini, I.; Cruise, M.; De Marchi, F.; Diaz-Aguilo, M.; Diepholz, I.; Dixon, G.; Dolesi, R.; Fauste, J.; Ferraioli, L.; Fertin, D.; Fichter, W.; Fitzsimons, E.; Freschi, M.; García Marirrodriga, C.; Gesa, L.; Gibert, F.; Giardini, D.; Grimani, C.; Grynagier, A.; Guillaume, B.; Guzmán, F.; Harrison, I.; Hewitson, M.; Hollington, D.; Hough, J.; Hoyland, D.; Hueller, M.; Huesler, J.; Jeannin, O.; Jennrich, O.; Jetzer, P.; Johlander, B.; Killow, C.; Llamas, X.; Lloro, I.; Lobo, A.; Maarschalkerweerd, R.; Madden, S.; Mance, D.; Mateos, I.; McNamara, P. W.; Mendes, J.; Mitchell, E.; Nicolini, D.; Nicolodi, D.; Pedersen, F.; Perreur-Lloyd, M.; Perreca, A.; Plagnol, E.; Prat, P.; Racca, G. D.; Rais, B.; Ramos-Castro, J.; Reiche, J.; Romera Perez, J. A.; Robertson, D.; Rozemeijer, H.; Sanjuan, J.; Schulte, M.; Shaul, D.; Stagnaro, L.; Strandmoe, S.; Sumner, T. J.; Taylor, A.; Texier, D.; Trenkel, C.; Tombolato, D.; Vitale, S.; Wanner, G.; Ward, H.; Waschke, S.; Wass, P.; Weber, W. J.; Zweifel, P.

    2011-05-01

    Preparations for the LISA Pathfinder mission have reached an exciting stage. Tests of the engineering model (EM) of the optical metrology system have recently been completed at the Albert Einstein Institute, Hannover, and flight model tests are now underway. Significantly, they represent the first complete integration and testing of the space-qualified hardware and are the first tests on an optical system level. The results and test procedures of these campaigns will be utilized directly in the ground-based flight hardware tests, and subsequently during in-flight operations. In addition, they allow valuable testing of the data analysis methods using the MATLAB-based LTP data analysis toolbox. This paper presents an overview of the results from the EM test campaign that was successfully completed in December 2009.

  13. Strong lensing of gravitational waves as seen by LISA.

    PubMed

    Sereno, M; Sesana, A; Bleuler, A; Jetzer, Ph; Volonteri, M; Begelman, M C

    2010-12-17

    We discuss strong gravitational lensing of gravitational waves from the merging of massive black hole binaries in the context of the LISA mission. Detection of multiple events would provide invaluable information on competing theories of gravity, evolution and formation of structures and, possibly, constraints on H0 and other cosmological parameters. Most of the optical depth for lensing is provided by intervening massive galactic halos, for which wave optics effects are negligible. Probabilities to observe multiple events are sizable for a broad range of formation histories. For the most optimistic models, up to ≲ 4 multiple events with a signal to noise ratio ≳ 8 are expected in a 5-year mission. Chances are significant even for conservative models with either light (≲ 60%) or heavy (≲ 40%) seeds. Because of lensing amplification, some intrinsically too faint signals are brought over threshold (≲ 2 per year).

  14. Precision Pointing for the Laser Interferometer Space Antenna (LISA) Mission

    NASA Technical Reports Server (NTRS)

    Bauer, Frank H. (Technical Monitor); Hyde, T. Tupper; Maghami, P.

    2003-01-01

    The Laser Interferometer Space Antenna (LISA) mission is a planned NASA-ESA gravity wave detector consisting of three spacecraft in heliocentric orbit. Lasers are used to measure distance fluctuations between the proof masses aboard the spacecraft to the picometer level over the 5 million kilometer spacing. Each spacecraft and it's two laser transmit/receive telescopes must be held stable in pointing to less than 8 nanoradians per root Hertz in the frequency band 0.1 mHz to 0.1 Hz. This is accomplished by sensing the pointing error in the received beam and controlling the spacecraft attitude with a set of micronewton thrusters. Requirements, sensors, actuators, control design, and simulations are described in this paper.

  15. THE LISA GRAVITATIONAL WAVE FOREGROUND: A STUDY OF DOUBLE WHITE DWARFS

    SciTech Connect

    Ruiter, Ashley J.; Belczynski, Krzysztof; Larson, Shane L. E-mail: kbelczyn@nmsu.ed E-mail: gabriel.j.williams@gmail.co

    2010-07-10

    Double white dwarfs (WDs) are expected to be a source of confusion-limited noise for the future gravitational wave observatory LISA. In a specific frequency range, this 'foreground noise' is predicted to rise above the instrumental noise and hinder the detection of other types of signals, e.g., gravitational waves arising from stellar-mass objects inspiraling into massive black holes. In many previous studies, only detached populations of compact object binaries have been considered in estimating the LISA gravitational wave foreground signal. Here, we investigate the influence of compact object detached and Roche-Lobe overflow (RLOF) Galactic binaries on the shape and strength of the LISA signal. Since >99% of remnant binaries that have orbital periods within the LISA sensitivity range are WD binaries, we consider only these binaries when calculating the LISA signal. We find that the contribution of RLOF binaries to the foreground noise is negligible at low frequencies, but becomes significant at higher frequencies, pushing the frequency at which the foreground noise drops below the instrumental noise to >6 mHz. We find that it is important to consider the population of mass-transferring binaries in order to obtain an accurate assessment of the foreground noise on the LISA data stream. However, we estimate that there still exists a sizeable number ({approx}11,300) of Galactic double WD binaries that will have a signal-to-noise ratio >5, and thus will be potentially resolvable with LISA. We present the LISA gravitational wave signal from the Galactic population of WD binaries, show the most important formation channels contributing to the LISA disk and bulge populations, and discuss the implications of these new findings.

  16. An intensive case analysis of client metacognition in a good-outcome psychotherapy: Lisa's case.

    PubMed

    Carcione, Antonino; Dimaggio, Giancarlo; Fiore, Donatella; Nicolo, Giuseppe; Procacci, Michele; Semerari, Antonio; Pedone, Roberto

    2008-11-01

    The authors analyzed the successful case of Lisa, a client with major depression, using the Metacognitive Assessment Scale (MAS). Consistently with the literature on depression, the authors hypothesize that Lisa's ability to reflect on mental states--here metacognition--is marginally affected. The authors found that Lisa was better at describing her own mind rather than understanding the mind of the others. Furthermore, the most severe impairment was in using metacognition to cope with mental state source of distress and to enact strategies to solve interpersonal problems. During the therapy such difficulties improved progressively. Limitations and implications of these findings are discussed.

  17. Science with the space-based interferometer LISA. IV: probing inflation with gravitational waves

    NASA Astrophysics Data System (ADS)

    Bartolo, Nicola; Caprini, Chiara; Domcke, Valerie; Figueroa, Daniel G.; Garcia-Bellido, Juan; Chiara Guzzetti, Maria; Liguori, Michele; Matarrese, Sabino; Peloso, Marco; Petiteau, Antoine; Ricciardone, Angelo; Sakellariadou, Mairi; Sorbo, Lorenzo; Tasinato, Gianmassimo

    2016-12-01

    We investigate the potential for the LISA space-based interferometer to detect the stochastic gravitational wave background produced from different mechanisms during inflation. Focusing on well-motivated scenarios, we study the resulting contributions from particle production during inflation, inflationary spectator fields with varying speed of sound, effective field theories of inflation with specific patterns of symmetry breaking and models leading to the formation of primordial black holes. The projected sensitivities of LISA are used in a model-independent way for various detector designs and configurations. We demonstrate that LISA is able to probe these well-motivated inflationary scenarios beyond the irreducible vacuum tensor modes expected from any inflationary background.

  18. Prognostic Discrepancy of the 6th and 7th UICC N Classification for Lymph Node Staging in Gastric Cancer Patients after Curative Resection

    PubMed Central

    Oh, Sung Jin; Suh, Byoung Jo; Park, Jong Kwon; Oh, Sung Don; Yu, Hang Jong

    2017-01-01

    Background The validity of N classification of the 7th edition of the American Joint Committee on Cancer/Union Internationale contre le Cancer (AJCC/UICC) tumor-node-metastasis (TNM) staging system is still under debate. The purpose of this study was to evaluate the prognostic efficacy of the 7th edition of the AJCC/UICC TNM staging system (focusing on N stage), in comparison with the 6th edition, at a single Eastern institution. Methods We analyzed 1,435 patients with gastric cancer who underwent curative resection performed from September 1998 to August 2003 at the Memorial Jin-Pok Kim Korea Gastric Cancer Center. We analyzed the survival rate of the patients according to the AJCC/UICC 6th and 7th editions, and compared each stage, focusing on N stage. Results Significant differences in the 5-year survival rates were observed between the 6th and the 7th AJCC/UICC staging system. In the 6th edition staging system, the Kaplan-Meier curves discriminated each N stage significantly. In contrast, there was no difference in terms of survival curves for N stage according to the 7th edition, especially between N1 and N2: the Kaplan-Meier plots of survival curves between N1 (77.0%) and N2 (78.1%) stages overlapped significantly (p < 0.05). Conclusion Although the 7th UICC staging system is a more detailed and sophisticated system in the T category, there was no prognostic significance between the pN1 and pN2 stages according to our data. Therefore, we suggest establishing a new UICC staging system taking into consideration the application of the N stage. PMID:28203165

  19. Proceedings of the International Conference of the International Group for the Psychology of Mathematics Education (7th, Jerusalem, Israel, July 24-29, 1983).

    ERIC Educational Resources Information Center

    Hershkowitz, Rina, Ed.

    This document contains plenary and contributed papers presented at the seventh PME meeting, held near Jerusalem, Israel in July 1983. Three plenary papers focused on implicit models in solving problems, discussions with teachers and children, and heuristics. Contributed papers were classified under seven headings: learning theories…

  20. Colloid micro-Newton thruster development for the ST7-DRS and LISA missions

    NASA Technical Reports Server (NTRS)

    Ziemer, John K.; Gamero-Castano, Manuel; Hruby, Vlad; Spence, Doug; Demmons, Nate; McCormick, Ryan; Roy, Tom

    2005-01-01

    We present recent progress and development of the Busek Colloid Micro-Newton Thruster (CMNT) for the Space Technology 7 Disturbance Reduction System (ST7-DRS) and Laser Interferometer Space Antenna (LISA) Missions.

  1. LISA Mission Concept Study, Laser Interferometer Space Antenna for the Detection and Observation of Gravitational Waves

    NASA Technical Reports Server (NTRS)

    Folkner, W. M.; Bender, P. L.; Stebbins, R. T.

    1998-01-01

    This document presents the results of a design feasibility study for LISA (Laser Interferometer Space Antenna). The goal of LISA is to detect and study low-frequency astrophysical gravitational radiation from strongly relativistic regions. Astrophysical sources potentially visible to LISA include extra-galactic massive black hole binaries at cosmological distances, binary systems composed of a compact star and a massive black hole, galactic neutron star-black hole binaries, and background radiation from the Big Bang. The LISA mission will comprise three spacecraft located five million kilometers apart forming an equilateral triangle in an Earth-trailing orbit. Fluctuations in separation between shielded test masses located within each spacecraft will be determined by optical interferometry which determines the phase shift of laser light transmitted between the test masses.

  2. Less invasive surfactant administration (LISA) - ways to deliver surfactant in spontaneously breathing infants.

    PubMed

    Herting, Egbert

    2013-11-01

    The idea to deliver surfactant to spontaneously breathing premature infants is not new. The spectrum of methods reported reaches from aerosol administration over pharyngeal deposition, the use of laryngeal masks, short term intubation, surfactant administration and rapid extubation (INSURE) to an approach of keeping premature neonates on spontaneous breathing with continuous positive airway pressure support and administering surfactant by laryngoscopy via a small diameter tube. This way of Less Invasive Surfactant Administration (LISA) is in increasing use in the last decade in Germany. More than 1000 babies have been included in clinical studies on LISA by now. A first prospective randomized controlled trial (AMV-trial) demonstrated a significant reduction in the use of mechanical ventilation in LISA patients compared to standard treatment with intratracheal bolus administration of surfactant. Another recent study (Take Care study) indicates, that LISA may even be superior to INSURE. The search for even more "gentle" methods (e.g. nebulization) to deliver surfactant continues.

  3. LISA Pathfinder and the road to space-based detection of gravitational waves

    NASA Astrophysics Data System (ADS)

    Thorpe, James

    2016-04-01

    The LISA Pathfinder spacecraft was launched on Dec 3rd, 2015 and began science operations in March 2016. Led by the European Space Agency with contributions from a number of European national agencies, universities, and NASA, LISA Pathfinder will demonstrate several key technologies and measurement technqiues for future space-based gravitational wave observatories. A successful LISA Pathfinder will retire much of the technical risk for such missions, which are the only proposed instruments capable of observing gravitational waves in the milliHertz band, a source-rich region expected to include singals from merging extragalactic massive black holes, capture of stellar-mass compact objects by massive black holes, and millions of individual close compact binaries in the Milky Way. I will present an overview of the LISA Pathfinder mission, it's current status, and the plans for operations and data analysis.

  4. Finally Here - The launch of LISA Pathfinder and the road to detecting Gravitational Waves in space

    NASA Astrophysics Data System (ADS)

    Thorpe, James; LISA Pathfinder Team

    2016-01-01

    The LISA Pathfinder spacecraft was launched in late 2015 and will begin science operations in early 2016. Led by the European Space Agency with contributions from a number of European national agencies, universities, and NASA, LISA Pathfinder will demonstrate several key technologies and measurement technqiues for future space-based gravitational wave observatories. A successful LISA Pathfinder will retire much of the technical risk for such missions, which are the only proposed instruments capable of observing gravitational waves in the milliHertz band, a source-rich region expected to include singals from merging extragalactic massive black holes, capture of stellar-mass compact objects by massive black holes, and millions of individual close compact binaries in the Milky Way. I will present an overview of the LISA Pathfinder mission, it's current status, and the plans for operations and data analysis.

  5. Magnetic field measurement using chip-scale magnetometers in eLISA

    NASA Astrophysics Data System (ADS)

    Mateos, I.; Diaz-Aguiló, M.; Gesa, L.; Gibert, F.; Karnesis, N.; Lloro, I.; Lobo, A.; Martín, V.; Nofrarias, M.; Ramos-Castro, J.; Sopuerta, C. F.

    2015-05-01

    Magnetic sensors are necessary devices to map the magnetic field and gradient at eLISA test masses location. Their primary goal is assessing the contribution of the magnetic effects to the acceleration noise budget. Our experience, accumulated during the magnetic diagnostics system design for LISA Pathfinder, indicates that the accuracy of the magnetic field map interpolation at the test mass is critical issue. Therefore, taking into consideration eLISA increased performance demands, an enhancement of the LISA Pathfinder magnetic subsystem is deemed necessary. A goal pursued by using alternative magnetic sensing techniques. In this study, the accuracy improvements in the magnetic field map reconstruction obtained with the currently conceived instrumental layout are demonstrated.

  6. [Case report of acute death on the 7th day due to exposure to the vapor of the insecticide chlorfenapyr].

    PubMed

    Hoshiko, Michiko; Naito, Shinji; Koga, Mitsuaki; Mori, Mihoko; Hara, Kunio; Ishitake, Tatsuya

    2007-04-01

    We present the case of a 55-year-old male agricultural worker who complained of severe general fatigue and hyperperspiration after exposure to an insecticide vapor. He worked in a tea plantation and used chlorfenapyr, a broad spectrum for harmful insects, without any protective mask or clothes. After one day of insecticide spray work, he gradually began to complain of general fatigue, hyperperspiration, nausea and vomiting. At first, he was diagnosed as being dehydrated and was treated with fluid replacement therapy. Although he received this conservative therapy, there was no effect on the above mentioned symptoms. On the 7th day of the onset of his symptoms, his consciousness level deteriorated rapidly and body temperature exceeded 40 degrees C. No cerebral vascular disease or meningitis was observed. Finally, he died despite intensive care. The findings of the clinical course and laboratory data suggest a clinical diagnosis of acute pesticide poisoning due to exposure to chlorfenapyr vapor. We suggest that agricultural workers should use this insecticide with caution and sufficient protective gear.

  7. Bond Strength of 5th, 6th and 7th Generation Bonding Agents to Intracanal Dentin of Primary Teeth

    PubMed Central

    Afshar, Hossein; Baradaran Nakhjavani, Yahya; Rahro Taban, Sedighe; Baniameri, Zahra; Nahvi, Azam

    2015-01-01

    Objectives: This in-vitro study sought to assess the push-out bond strength of a total etch and 2 self-etch bonding systems to intracanal dentin of primary anterior teeth (PAT). Materials and Methods: Thirty-six primary anterior teeth were randomly divided into 3 groups of 5th generation (Single Bond 2), 6th generation (Clearfil SE) and 7th generation (Single Bond Universal) bonding agents. The canal orifice was restored with composite resin and the push-out test was carried out to assess the bond strength. After applying the push-out load, specimens were evaluated under a light microscope at 40X magnification. One-way ANOVA and log-rank test on Kaplan-Meier curves were applied for the comparison of bond strength among the 3 groups. Results: The mean± standard deviation (SD) bond strength was 13.6±5.33 MPa for Single Bond 2, 13.85±5.86 MPa for Clearfil SE and 12.28±5.24 MPa for Single Bond Universal. The differences in bond strength among the 3 groups were not statistically significant (P>0.05). Conclusion: All three bonding agents are recommended for use with composite posts in PAT. However, due to high technical sensitivity of the Total Etch system, single or two-step self etch systems may be preferred for uncooperative children. PMID:26056518

  8. Assessment of nutrition and physical activity of 6th–7th grade schoolchildren in the city of Vilnius, Lithuania

    PubMed Central

    Skurdenyte, Vaida; Surkiene, Gene; Stukas, Rimantas; Zagminas, Kestutis; Giedraitis, Vincentas

    2015-01-01

    Background Evaluation of eating habits and physical activity is very important for health interventions. Our aim in this study was to assess the characteristics of eating and physical activity of 6–7th grade schoolchildren in the city of Vilnius, Lithuania, as well as the association between dietary habits and physical activity. Methods The study was conducted within the project “Education of healthy diets and physical activity in schools”. The sample consisted of 1008 schoolchildren from 22 schools in the city of Vilnius, and was based on empirical methods, including a questionnaire poll and comparative analysis. Statistical software Stata v.12.1 (Stata corp LP) was used to analyze the data. Results Our study showed that less than half (37.1%) of study participants had physically active leisure time. Boys were significantly more physically active than girls. More than half (61.4%) of children ate breakfast every day. Girls were more likely to eat vegetables and sweets. Schoolchildren who ate vegetables and dairy products as well as those who got enough information about physical activity and spoke about it with their family members were more physically active. Conclusions The results of the study confirmed that schoolchildren were not sufficiently physically active. It was found that low physical activity is related to dietary and other factors, such as lack of information about physical activity and its benefits. PMID:28352688

  9. On the role of radiation monitors on board LISA Pathfinder and future space interferometers

    NASA Astrophysics Data System (ADS)

    Grimani, C.; Boatella, C.; Chmeissani, M.; Fabi, M.; Finetti, N.; Laurenza, M.; Lobo, A.; Mateos, I.; Storini, M.

    2012-05-01

    LISA (Laser Interferometer Space Antenna) and its precursor mission LISA Pathfinder (LISA-PF) will carry particle monitors for noise diagnostics. It was proposed to build and place radiation detectors on board the ASTROD missions as well. We present here a study of the solar energetic particle (SEP) events that the LISA-PF radiation monitors are able to detect above the galactic cosmic-ray (GCR) background predicted at the time of the mission data taking in 2015. In order to optimize the correlation between radiation monitor measurements and gravitational sensor test-mass charging, the energy threshold for particles traversing both detectors should be approximately the same. In LISA-PF, the radiation monitor particle energy cut-off was conservatively set at 75 MeV per nucleon (MeV/n) for protons and ion normal incidence, while the minimum energy of the same particles reaching the test masses is 100 MeV/n. We find that SEP events detectable on LISA-PF are characterized by peak fluxes and fluences at energies >75 MeV/n larger than about 45%, on average, with respect to those at energies >100 MeV/n. We conclude that for an accurate correlation between radiation monitor count rates and test-mass charging, it is mandatory to benefit from absolute flux measurements of both galactic and high-energy solar particles provided by experiments carrying magnetic spectrometers in space at the time of LISA-PF (PAMELA, AMS). On the other hand, the role of the radiation detectors on board LISA-PF is crucial allowing for SEP event onset and dynamics monitoring.

  10. Multiple Sun-Earth Saddle Point flybys for LISA Pathfinder

    NASA Astrophysics Data System (ADS)

    Fabacher, Emilien; Kemble, Stephen; Trenkel, Christian; Dunbar, Neil

    2013-07-01

    LISA Pathfinder is an ESA mission due to be launched in the next two years. The gravity gradiometer onboard has the sensitivity required to test predictions by gravitational theories proposed as alternatives to Dark Matter such as TeVeS. Within the Solar System measurable effects are predicted only in the vicinity of gravitational saddle points (SP). For this reason it has been proposed to fly LPF by the Earth-Sun SP, at some 259,000 km from Earth. This could be done in an extension to the nominal mission which uses a Lissajous orbit about the Earth-Sun L1 point. The responsibility for LPF mission design lies with ESA/ESOC, who have designed the transfer trajectories, orbits about L1, and station keeping strategies. This article describes an analysis performed by Astrium to support a suggestion for a possible mission extension to a saddle point crossing. With only very limited fuel availability, reaching the saddle point is a significant challenge. In this article, we present recent advances in the work on trajectory design. It is demonstrated that reaching the SP is feasible once the LPF mission is completed. Furthermore, in a significant enhancement, it is demonstrated that trajectories including more than one SP flyby are possible, thus improving the science return for this proposed mission extension.

  11. Binary Black Hole Mergers, Gravitational Waves, and LISA

    NASA Astrophysics Data System (ADS)

    Centrella, Joan; Baker, J.; Boggs, W.; Kelly, B.; McWilliams, S.; van Meter, J.

    2007-12-01

    The final merger of comparable mass binary black holes is expected to be the strongest source of gravitational waves for LISA. Since these mergers take place in regions of extreme gravity, we need to solve Einstein's equations of general relativity on a computer in order to calculate these waveforms. For more than 30 years, scientists have tried to compute black hole mergers using the methods of numerical relativity. The resulting computer codes have been plagued by instabilities, causing them to crash well before the black holes in the binary could complete even a single orbit. Within the past few years, however, this situation has changed dramatically, with a series of remarkable breakthroughs. We will present the results of new simulations of black hole mergers with unequal masses and spins, focusing on the gravitational waves emitted and the accompanying astrophysical "kicks.” The magnitude of these kicks has bearing on the production and growth of supermassive blackholes during the epoch of structure formation, and on the retention of black holes in stellar clusters. This work was supported by NASA grant 06-BEFS06-19, and the simulations were carried out using Project Columbia at the NASA Advanced Supercomputing Division (Ames Research Center) and at the NASA Center for Computational Sciences (Goddard Space Flight Center).

  12. Observing Mergers of Nonspinning Black Hole Binaries with LISA

    NASA Technical Reports Server (NTRS)

    McWilliams S.; Baker, John G.; Boggs, William D.; Centrella, Joan; Kelly Bernard J.; Thorpe, J. Ira; vanMeter, James R.

    2008-01-01

    Recent advances in the field of numerical relativity now make it possible to calculate the final, most powerful merger phase of binary black hole coalescence. We present the application of nonspinning numerical relativity waveforms to the search for and precision measurement of black hole binary coalescences using LISA. In particular, we focus on the advances made in moving beyond the equal mass, nonspinning case into other regions of parameter space, focusing on the case of nonspinning holes with ever-increasing mass ratios. We analyze the available unequal mass merger waveforms from numerical relativity, and compare them to two models, both of which use an effective one body treatment of the inspiral, but which use fundamentally different approaches to the treatment of the merger-ringdown. We confirm the expected mass ratio scaling of the merger, and investigate the changes in waveform behavior and their observational impact with changing mass ratio. Finally, we investigate the potential contribution from the merger portion of the waveform to measurement uncertainties of the binary's parameters for the unequal mass case.

  13. Binary Black Hole Mergers, Gravitational Waves, and LISA

    NASA Technical Reports Server (NTRS)

    Centrella, Joan; Baker, J.; Boggs, W.; Kelly, B.; McWilliams, S.; vanMeter, J.

    2008-01-01

    The final merger of comparable mass binary black holes is expected to be the strongest source of gravitational waves for LISA. Since these mergers take place in regions of extreme gravity, we need to solve Einstein's equations of general relativity on a computer in order to calculate these waveforms. For more than 30 years, scientists have tried to compute black hole mergers using the methods of numerical relativity. The resulting computer codes have been plagued by instabilities, causing them to crash well before the black holes in the binary could complete even a single orbit. Within the past few years, however, this situation has changed dramatically, with a series of remarkable breakthroughs. We will present the results of new simulations of black hole mergers with unequal masses and spins, focusing on the gravitational waves emitted and the accompanying astrophysical "kicks." The magnitude of these kicks has bearing on the production and growth of supermassive black holes during the epoch of structure formation, and on the retention of black holes in stellar clusters.

  14. Constraining stellar binary black hole formation scenarios with eLISA eccentricity measurements

    NASA Astrophysics Data System (ADS)

    Nishizawa, Atsushi; Sesana, Alberto; Berti, Emanuele; Klein, Antoine

    2017-03-01

    A space-based interferometer such as the evolved Laser Interferometer Space Antenna (eLISA) could observe a few to a few thousands of progenitors of black hole binaries (BHBs) similar to those recently detected by Advanced LIGO. Gravitational radiation circularizes the orbit during inspiral, but some BHBs retain a measurable eccentricity at the low frequencies where eLISA is the most sensitive. The eccentricity of a BHB carries precious information about its formation channel: BHBs formed in the field, in globular clusters, or close to a massive black hole (MBH) have distinct eccentricity distributions in the eLISA band. We generate mock eLISA observations, folding in measurement errors, and using a Bayesian model selection, we study whether eLISA measurements can identify the BHB formation channel. We find that a handful of observations would suffice to tell whether BHBs were formed in the gravitational field of an MBH. Conversely, several tens of observations are needed to tell apart field formation from globular cluster formation. A 5-yr eLISA mission with the longest possible armlength is desirable to shed light on BHB formation scenarios.

  15. Thermal gradient-induced forces on geodesic reference masses for LISA

    SciTech Connect

    Carbone, L.; Ciani, G.; Dolesi, R.; Hueller, M.; Tombolato, D.; Vitale, S.; Weber, W. J.; Cavalleri, A.

    2007-11-15

    The low frequency sensitivity of space-borne gravitational wave observatories will depend critically on the geodesic purity of the trajectories of orbiting test masses. Fluctuations in the temperature difference across the enclosure surrounding the free-falling test mass can produce noisy forces through several processes, including the radiometric effect, radiation pressure, and outgassing. We present here a detailed experimental investigation of thermal gradient-induced forces for the Laser Interferometer Space Antenna (LISA) gravitational wave mission and the LISA Pathfinder, employing high resolution torsion pendulum measurements of the torque on a LISA-like test mass suspended inside a prototype of the LISA gravitational reference sensor that will surround the test mass in orbit. The measurement campaign, accompanied by numerical simulations of the radiometric and radiation pressure effects, allows a more accurate and representative characterization of thermal-gradient forces in the specific geometry and environment relevant to LISA free-fall. The pressure dependence of the measured torques allows clear identification of the radiometric effect, in quantitative agreement with the model developed. In the limit of zero gas pressure, the measurements are most likely dominated by outgassing, but at a low level that does not threaten the current LISA noise estimate, which assumes a maximum net force per degree of temperature difference of 100(pN/K) for the overall thermal gradient-induced effects.

  16. Constraining stellar binary black hole formation scenarios with LISA eccentricity measurements

    NASA Astrophysics Data System (ADS)

    Berti, Emanuele; Nishizawa, Atsushi; Sesana, Alberto; Klein, Antoine

    2017-01-01

    A space-based interferometer such as LISA could observe few to few thousands progenitors of black hole binaries (BHBs) similar to those recently detected by Advanced LIGO. Gravitational radiation circularizes the orbit during inspiral, but some BHBs retain a measurable eccentricity at the low frequencies where LISA is most sensitive. The eccentricity of a BHB carries precious information about its formation channel: BHBs formed in the field, in globular clusters, or close to a massive black hole (MBH) have distinct eccentricity distributions in the LISA band. We generate mock LISA observations, folding in measurement errors, and using Bayesian model selection we study whether LISA measurements can identify the BHB formation channel. We find that a handful of observations would suffice to tell whether BHBs were formed in the gravitational field of a MBH. Conversely, several tens of observations are needed to tell apart field formation from globular cluster formation. A five-year LISA mission with the longest possible armlength is desirable to shed light on BHB formation scenarios. NSF CAREER Grant No. PHY-1055103, NSF Grant No. PHY-1607130, FCT contract IF/00797/2014/CP1214/CT0012.

  17. Use of Jigsaw Technique to Teach the Unit "Science within Time" in Secondary 7th Grade Social Sciences Course and Students' Views on This Technique

    ERIC Educational Resources Information Center

    Yapici, Hakki

    2016-01-01

    The aim of this study is to apply the jigsaw technique in Social Sciences teaching and to unroll the effects of this technique on learning. The unit "Science within Time" in the secondary 7th grade Social Sciences text book was chosen for the research. It is aimed to compare the jigsaw technique with the traditional teaching method in…

  18. Determining the Effects of Using Different Writing Activities on the Academic Achievements Secondary School 7th Grade Students and Their Attitudes Towards the Course

    ERIC Educational Resources Information Center

    Uzoglu, Mustafa

    2014-01-01

    The purpose of the study is to determine the effects of using writing activities with different learning purposes by the secondary school 7th grade students on their academic achievement and attitudes towards the course. The study was carried out in a secondary school located in the centre of Erzurum in 2012-2013 academic year; the study is a…

  19. Studying the Ability of 7th Grade Students to Define the Circle and Its Elements in the Context of Mathematical Language

    ERIC Educational Resources Information Center

    Akarsu, Esra; Yilmaz, Süha

    2015-01-01

    In this study, it was aimed to study the mathematical language skills that the 7th grade students use in defining the circle and its elements. In the study, the mathematical language skills of students that they use in defining the circle and its elements in a scenario were compared to the mathematical language skills they use in defining them…

  20. Research Examination of the Options to Increase the Education Effectiveness in the Technical Subjects at the 7th Grade of Elementary School Using Hypertext Educational Material

    ERIC Educational Resources Information Center

    Žácok, L'ubomir

    2010-01-01

    The utilization of hypertext educational material is going to be solved in this paper as a source using which the effectiveness of education the technical subjects at the 7th grade of elementary school can be increased. As a comparison between reached results in the control and experimental groups of pupils we used final didactical examination,…

  1. The Effect of Learning Geometry Topics of 7th Grade in Primary Education with Dynamic Geometer's Sketchpad Geometry Software to Success and Retention

    ERIC Educational Resources Information Center

    Kesan, Cenk; Caliskan, Sevdane

    2013-01-01

    The aim of this study is to investigate the effect of learning geometry topics of 7th grade in primary education with dynamic geometer's sketchpad geometry software to student's success and retention. The experimental research design with The Posttest-Only Control Group was used in this study. In the experimental group, dynamic geometer's…

  2. Influence of Skip Patterns on Item Non-Response in a Substance Use Survey of 7th to 12th Grade Students

    ERIC Educational Resources Information Center

    Ding, Kele; Olds, R. Scott; Thombs, Dennis L.

    2009-01-01

    This retrospective case study assessed the influence of item non-response error on subsequent response to questionnaire items assessing adolescent alcohol and marijuana use. Post-hoc analyses were conducted on survey results obtained from 4,371 7th to 12th grade students in Ohio in 2005. A skip pattern design in a conventional questionnaire…

  3. Assessing the Development of Environmental Virtue in 7th and 8th Grade Students in an Expeditionary Learning Outward Bound School

    ERIC Educational Resources Information Center

    Martin, Bruce; Bright, Alan; Cafaro, Philip; Mittelstaedt, Robin; Bruyere, Brett

    2009-01-01

    This study attempted to assess the development of environmental virtue in 7th and 8th grade students in an Expeditionary Learning Outward Bound (ELOB) school using an instrument developed for this study--the Children's Environmental Virtue Scale (CEVS). Data for this study were obtained by administering the CEVS survey (pretest and posttest) to…

  4. Making the Grade: Do Nebraska Teachers and Administrators Working in Public Schools in 7th-12th Grade Settings Agree about What Constitutes Sound Grading Practice?

    ERIC Educational Resources Information Center

    Olson, Mark E.

    2013-01-01

    In this study, the researcher sought to determine whether Nebraska teachers and administrators agreed about what constitutes sound grading practice. The results of this study indicated that Nebraska teachers and administrators working in public schools in 7th-12th grade settings did not always agree about what constituted sound grading practice.…

  5. [A development of Byzantine Christian charities during the 4(th)-7(th) centuries and the birth of the hospital].

    PubMed

    Nam, Sung Hyun

    2015-04-01

    This study aims to examine the beginning and the development of Christian Charities during the 4(th)-6(th) centuries which would eventually result in the birth of the hospital in modern sense in the first half of the 7(th) century. For this purpose, I looked carefully into various primary sources concerning the early Christian institutions for the poor and the sick. Above all, it's proper to note that the first xenodocheion where hospitality was combined with a systematic caring, is concerned with the Trinitarian debate of the 4(th) century. In 356, Eustathios, one of the leaders of homoiousios group, established xenodocheion to care for the sick and the lepers in Sebaste of Armenia, whereas his opponent Aetios, doctor and leader of the heteroousios party, was reckoned to have combined the medical treatment with his clerical activities. Then, Basil of Caesarea, disciple of Eustathios of Sebaste, also founded in 372 a magnificent benevolent complex named 'Basileias' after its founder. I scrupulously analysed several contemporary materials mentioning the charitable institution of Caesarea which was called alternatively katagogia, ptochotropheion, xenodocheion. John Chrysostome also founded several nosokomeia in Constantinople at the end of the 4(th) century and the beginning of the 5(th) century. Apparently, the contemporary sources mention that doctors existed for these Charities, but there is no sufficient proof that these 'Christian Hospitals,' Basileias or nosokomeia of Constantinople were hospitals in modern sense. Imperial constitutions began to mention ptochotropheion, xenodocheion and orphanotropheion since the second half of the 5(th) century and then some Justinian laws evoked nosokomium, brephotrophia, gerontocomia. These laws reveal that 'Christian Hospitals' were well clarified and deeply rooted in Byzantine society already in these periods. And then, new benevolent institutions emerged in the 6(th) century: nosokomeia for a specific class and

  6. Precision Measurement of Black Hole Binary Dynamics: Analyzing the LISA Data Stream

    NASA Astrophysics Data System (ADS)

    McWilliams, Sean T.; Thorpe, James Ira; Baker, John G.; Arnaud, Keith A.; Kelly, Bernard J.

    One of the richest potential sources of insight into fundamental physics that LISA will be capable of observing is the inspiral of supermassive black hole binaries (BHBs). However, the data analysis challenge presented by the LISA data stream is quite unlike the situation for present day gravitational wave detectors. In order to make the precision measurements necessary to achieve LISA's science goals, the BHB signal must be distinguished from a data stream that not only contains instrumental noise, but potentially thousands of other signals as well, so that the "background" we wish to separate out to focus on the BHB signal is likely to be highly nonstationary and nongaussian, as well as being of scientific interest in its own right. In addition, whereas the theoretical templates that we calculate in order to ultimately estimate the parameters can afford to be somewhat inaccurate and still be effective for presentday and near future detectors, this is not the case for LISA, and extremely high fidelity of the theoretical templates for high signal-to-noise signals will be required to prevent theoretical errors from dominating the parameter estimates. We will describe efforts in the community of LISA data analysts to address the challenges regarding the specific issue of BHB signals. These efforts include using a Markov Chain Monte Carlo approach with the freedom to model the BHB and the other signals present in the data stream simultaneously, rather than trying to remove other signals and risk biasing the remaining data. The Mock LISA Data Challenge is a community of LISA scientists who generate rounds of simulated LISA noise with increasingly difficult signal content, and invite the LISA data analysis community to exercise their methods, or develop new methods, in an attempt to extract the parameters for the signals embedded in the mock data. In addition to practical approaches such as this to assess the level of parameter accuracy, one can apply the Fisher matrix

  7. Can we improve breast cancer mortality in Okinawa? Consensus of the 7th Okinawa Breast Oncology Meeting.

    PubMed

    Tamaki, Kentaro; Tamaki, Nobumitsu; Kamada, Yoshihiko; Uehara, Kano; Zaha, Hisamitsu; Onomura, Mai; Ueda, Makoto; Kurashita, Kaname; Miyazato, Keiko; Higa, Junko; Miyara, Kyuichiro; Shiraishi, Makiko; Murayama, Shigemi; Ishida, Takanori

    2015-01-01

    The rate of breast cancer mortality in Okinawa has gradually been increasing up to 2010. Now Okinawa has the second worst mortality rate in Japan, in part due to the enormous dietary changes resulting from the post-World War II US military occupation, high incidence of obesity, high non-optimal treatment rate, and low breast-cancer screening rate. To reduce breast cancer mortality in Okinawa, we established the Okinawa Breast Oncology Meeting (OBOM) in 2012. At the 7th OBOM held on January 10th, 2014, we discussed the breast cancer mortality in Okinawa focusing on lifestyle, breast cancer screening and optimal treatments. The Okinawan women who were overweight and/or obese during premenopausal and postmenopausal ages had a statistically significant higher risk of breast cancer development compared to those with non-overweight and/or obese women. The traditional diet of Okinawa consists of foods low in calories but rich in nutritional value. Therefore, we recommend Okinawan people not to forget the Okinawan traditional lifestyle, and to reduce their bodyweight to prevent breast cancer. One of the main goals of the OBOM is to raise breast cancer screening attendance rates to 50% (29.2% in 2010). We should standardize the quality control for breast cancer screening in Okinawa. It is important to continue enlightening the Okinawan population to receive optimal treatment. In addition, we are striving to establish systematic medical cooperation between the hospitals specializing in breast cancer treatment with rural hospitals. The OBOM group endeavors to contribute to the improvement of breast cancer mortality in Okinawa.

  8. Alloy characterization of a 7th Century BC archeological bronze vase - Overcoming patina constraints using Monte Carlo simulations

    NASA Astrophysics Data System (ADS)

    Manso, M.; Schiavon, N.; Queralt, I.; Arruda, A. M.; Sampaio, J. M.; Brunetti, A.

    2015-05-01

    In this work we evaluate the composition of a bronze alloy using X-ray fluorescence spectrometry (XRF) and Monte Carlo (MC) simulations. For this purpose, a 7th Century BC archeological vase from the SW Iberian Peninsula, displaying a well formed corrosion patina was analyzed by means of a portable X-ray fluorescence spectrometer. Realistic MC simulations of the experimental setup were performed with the XRMC code package which is based on an intensive use of variance-reduction techniques and uses XRAYLIB a constantly updated X-ray library of atomic data. A single layer model was applied for simulating XRF of polished/pristine bronze whereas a two-or-three-layer model was developed for bronze covered respectively by a corrosion patina alone or coupled with a superficial soil derived crust. These simulations took into account corrosion (cerussite (PbCO3), cuprite (Cu2O), malachite (Cu2CO3(OH)2), litharge (PbO)) and soil derived products (goethite (FeO(OH)) and quartz (SiO2)) identified by means of X-ray diffraction and Raman micro analytical techniques. Results confirm previous research indicating that the XRF/Monte Carlo protocol is well suited when a two-layered model is considered, whereas in areas where the patina + soil derived products' crust is too thick, X-rays from the alloy substrate are not able to exit the sample. Quantitative results based on MC simulations indicate that the vase is made of a lead-bronze alloy: Mn (0.2%), Fe (1.0%), Cu (81.8%), As (0.5%), Ag (0.6%), Sn (8.0%) and Pb (8.0%).

  9. Balancing acts: A mixed methods study of the figured world of African American 7th graders in urban science classrooms

    NASA Astrophysics Data System (ADS)

    Cleveland-Solomon, Tanya E.

    What beliefs and cultural models do youth who are underrepresented in science have about the domain of science and about themselves as science learners? What do they imagine is possible for them in relation to science both now and in the future? In other words, what constitutes their figured world of science? This dissertation study, using a mixed methods design, offers new perspectives on the ways that underrepresented youth's unexamined assumptions or cultural models and resources may shape their identities and motivation to learn science. Through analyses of survey and interview data, I found that urban African American youths' social context, gender, racial identity, and perceptions of the science they had in school influenced their motivation to learn science. Analyses of short-term classroom observations and interviews suggested that students had competing cultural models that they used in their constructions of identities as science learners, which they espoused and adopted in relation to how well they leveraged the science-related cultural resources available to them. Results from this study suggested that these 7th graders would benefit from access to more expansive cultural models through access to individuals with scientific capital as a way to allow them to create fruitful identities as science learners. If we want to ensure that students from groups that are underrepresented in science not only have better outcomes, but aspire to and enter the science career pipeline, we must also begin to support them in their negotiations of competing cultural models that limit their ability to adopt science-learner identities in their classrooms. This study endeavored to understand the particular cultural models and motivational beliefs that drive students to act, and what types of individuals they imagine scientists and science workers to be. This study also examined how cultural models and resources influence identity negotiation, specifically the roles youths

  10. Detection and measurement of micrometeoroids with LISA Pathfinder

    NASA Astrophysics Data System (ADS)

    Thorpe, J. I.; Parvini, C.; Trigo-Rodríguez, J. M.

    2016-02-01

    The Solar System contains a population of dust and small particles originating from asteroids, comets, and other bodies. These particles have been studied using a number of techniques ranging from in-situ satellite detectors to analysis of lunar microcraters to ground-based observations of zodiacal light. In this paper, we describe an approach for using the LISA Pathfinder (LPF) mission as an instrument to detect and characterize the dynamics of dust particles in the vicinity of Earth-Sun L1. Launched on Dec. 3rd, 2015, LPF is a dedicated technology demonstrator mission that will validate several key technologies for a future space-based gravitational-wave observatory. The primary science instrument aboard LPF is a precision accelerometer which we show will be capable of sensing discrete momentum impulses as small as 4 × 10-8 N s. We then estimate the rate of such impulses resulting from impacts of micrometeoroids based on standard models of the micrometeoroid environment in the inner solar system. We find that LPF may detect dozens to hundreds of individual events corresponding to impacts of particles with masses >10-9g during LPF's roughly six-month science operations phase in a 5 × 105 km by 8 × 105 km Lissajous orbit around L1. In addition, we estimate the ability of LPF to characterize individual impacts by measuring quantities such as total momentum transferred, direction of impact, and location of impact on the spacecraft. Information on flux and direction provided by LPF may provide insight as to the nature and origin of the individual impact and help constrain models of the interplanetary dust complex in general. Additionally, this direct in situ measurement of micrometeoroid impacts will be valuable to designers of future spacecraft targeting the environment around L1.

  11. Precision Measurement of Black Hole Binary Dynamics: Analyzing the LISA Data Stream

    NASA Technical Reports Server (NTRS)

    McWilliams, Sean T.; Thorpe, James Ira; Baker, John G.; Arnaud, Keith A.; Kelly, Bernard J.

    2008-01-01

    One of the richest potential sources of insight into fundamental physics that LISA will be capable of observing is the inspiral of supermassive black hole binaries (BHBs). However, the data analysis challenge presented by the LISA data stream is quite unlike the situation for present day gravitational wave detectors. In order to make the precision measurements necessary to achieve LISA's science goals, the BHB signal must be distinguished from a data stream that not only contains instrumental noise, but potentially thousands of other signals as well, so that the "background" we wish to separate out to focus on the BHB signal is likely to be highly nonstationary and nongaussian, as well as being of scientific interest in its own right. In addition, whereas the theoretical templates that we calculate in order to ultimately estimate the parameters can afford to be somewhat inaccurate and still be effective for present day and near future detectors, this is not the case for LISA, and extremely high fidelity of the theoretical templates for high signal-to-noise signals will be required to prevent theoretical errors from dominating the parameter estimates. NVe, will describe efforts in the community of LISA data analysts to address the challenges regarding the specific issue of BHB signals. These efforts include using a Markov Chain Monte Carlo approach with the freedom to model the BHB and the other signals present in the data stream simultaneously, rather than trying to remove other signals and risk biasing the remaining data. The Mock LISA Data Challenge is a community of LISA scientists who generate rounds of simulated LISA noise with increasingly difficult signal content, and invite the LISA data analysis community to exercise their methods, or develop new methods, in an attempt to extract the parameters for the signals embedded in the mock data. In addition to practical approaches such ,is this to assess the level of parameter accuracy, one can apply the Fisher

  12. 7th U.S. / Japan Natural Resources (UJNR) Panel on Earthquake Research: Abstract Volume and Technical Program

    USGS Publications Warehouse

    Detweiler, Shane T.; Ellsworth, William L.

    2008-01-01

    making information public in a timely manner. The Panel visited sites along the east coast of Shikoku that were inundated by the tsunami caused by the 1946 Nankai earthquake where they heard from survivors of the disaster and saw new tsunami shelters and barriers. They also visited the Median Tectonic Line, a major onshore strike-slip fault on Shikoku. The 7th Joint Panel meeting was held in Seattle, Wash., U.S.A. from October 27-30, 2008.

  13. The status, achievements, and prospects of the Mock LISA Data Challenges

    NASA Astrophysics Data System (ADS)

    Vallisneri, Michele

    2009-05-01

    For the last three years, many gravitational-wave analysts around the world have supported the Mock LISA Data Challenges (MLDCs), a program to demonstrate and encourage the development of LISA data-analysis capabilities, tools and techniques. In the MLDCs, a task force chartered by the LIST periodically issues challenge data sets containing GW signals from sources of undisclosed parameters, embedded in synthetic LISA noise. Challenge participants have a few months to analyze the data and submit detection candidates, which are then compared with the sources originally injected in the data sets. In this talk, I review the milestones achieved in the first three MLDCs, and I describe Challenge 3 (for which, at the time of this meeting, we will have just received participant entries). I discuss how future challenge problems may broaden in scope from the technical analysis of LISA data to the investigation of LISA's science objectives, and to a systematic characterization of the instrument effects that will affect data analysis.

  14. Expanding applications for surface-contaminant sensing using the laser interrogation of surface agents (LISA) technique

    NASA Astrophysics Data System (ADS)

    Ponsardin, Patrick L.; Higdon, N. S.; Chyba, Thomas H.; Armstrong, Wayne T.; Sedlacek, Arthur J., III; Christesen, Steven D.; Wong, Anna

    2004-02-01

    Laser Interrogation of Surface Agents (LISA) is a UV-Raman technique that provides short-range standoff detection and identification of surface-deposited chemical agents. ITT Industries, Advanced Engineering and Sciences Division, is currently developing and expanding the LISA technology under several programs that span a variety of missions for homeland defense. We will present and discuss some of these applications, while putting in perspective the overall evolution undergone by the technique within the last years. These applications include LISA-Recon (now called the Joint Contaminated Surface Detector--JCSD) which was developed under a cost-sharing arrangement with the U.S. Army Soldier and Biological Chemical Command (SBCCOM) for incorporation on the Army"s future reconnaissance vehicles, and designed to demonstrate single-shot on-the-move measurements of chemical contaminants at concentration levels below the Army's requirements. In parallel, LISA-Shipboard is being developed to optimize the sensor technique for detection of surface contaminants in the operational environment of a ship. The most recently started activity is LISA-Inspector that is being developed to provide a transportable sensor in a 'cart-like' configuration.

  15. Hybrid local FEM/global LISA modeling of damped guided wave propagation in complex composite structures

    NASA Astrophysics Data System (ADS)

    Shen, Yanfeng; Cesnik, Carlos E. S.

    2016-09-01

    This paper presents a new hybrid modeling technique for the efficient simulation of guided wave generation, propagation, and interaction with damage in complex composite structures. A local finite element model is deployed to capture the piezoelectric effects and actuation dynamics of the transmitter, while the global domain wave propagation and interaction with structural complexity (structure features and damage) are solved utilizing a local interaction simulation approach (LISA). This hybrid approach allows the accurate modeling of the local dynamics of the transducers and keeping the LISA formulation in an explicit format, which facilitates its readiness for parallel computing. The global LISA framework was extended through the 3D Kelvin-Voigt viscoelasticity theory to include anisotropic damping effects for composite structures, as an improvement over the existing LISA formulation. The global LISA framework was implemented using the compute unified device architecture running on graphic processing units. A commercial preprocessor is integrated seamlessly with the computational framework for grid generation and material property allocation to handle complex structures. The excitability and damping effects are successfully captured by this hybrid model, with experimental validation using the scanning laser doppler vibrometry. To demonstrate the capability of our hybrid approach for complex structures, guided wave propagation and interaction with a delamination in a composite panel with stiffeners is presented.

  16. LISA Pathfinder: testing the limits of pure geodesic motion for gravitational wave observation in space

    NASA Astrophysics Data System (ADS)

    Weber, William

    2009-05-01

    Placing a gravitational reference test mass in nearly perfect geodesic motion, without any perturbing forces, is a critical problem for space-based gravitational wave detection and for a wide class of precision gravitational measurements. For the Laser Interferometer Space Antenna (LISA), high resolution observation of gravitational radiation from distant coalescing massive black holes will require that the geodesic reference test masses that serve as interferometry end mirrors be in free-fall to within a residual acceleration noise of order femto-m / s^2/ √Hz at frequencies near 0.1 mHz. The LISA Pathfinder mission, scheduled for launch by ESA and NASA in 2010, aims to demonstrate geodesic purity for a LISA-like test mass inside a co-orbiting spacecraft at a level approaching this LISA free-fall goal. In this talk, I will discuss the LISA Pathfinder flight experiment and what we have learned, in ground-based preparations for the mission, about the limits of free-fall that are relevant to gravitation wave detection and to other precise small force measurements.

  17. Verification of time-delay interferometry techniques using the University of Florida LISA interferometry simulator

    NASA Astrophysics Data System (ADS)

    Mitryk, Shawn J.; Wand, Vinzenz; Mueller, Guido

    2010-04-01

    Laser Interferometer Space Antenna (LISA) is a cooperative NASA/ESA mission proposed to directly measure gravitational waves (GW) in the frequency range from 30 \\,\\mu \\rm {Hz} to 1\\,\\rm {Hz} with an optimal strain sensitivity of 10^{-21}/\\sqrt{Hz} at 3\\,\\rm {mHz}. LISA will utilize a modified Michelson interferometer to measure length changes of 40\\,\\rm {pm}/\\sqrt{Hz} between drag-free proof masses located on three separate spacecraft (SC) separated by a distance of 5\\,\\rm {Gm}. The University of Florida has developed a hardware-in-the-loop simulator of the LISA constellation to verify the laser noise cancellation technique known as time-delay interferometry (TDI). We replicate the frequency stabilization of the laser on the local SC and the phase-locking of the lasers on the far SC. The laser photodetector beatnotes are electronically delayed, Doppler shifted and applied with a mock GW signal to simulate the laser link between the SC. The beatnotes are also measured with a LISA-like phasemeter and the data are used to extract the laser phase and residual phase-lock loop noise in post-processing through TDI. This uncovers the GW modulation signal buried under the laser noise. The results are then compared to the requirements defined by the LISA science collaboration.

  18. Sub-Femto-g Free Fall for Space-Based Gravitational Wave Observatories: LISA Pathfinder Results

    NASA Astrophysics Data System (ADS)

    Armano, M.; Audley, H.; Auger, G.; Baird, J. T.; Bassan, M.; Binetruy, P.; Born, M.; Bortoluzzi, D.; Brandt, N.; Caleno, M.; Carbone, L.; Cavalleri, A.; Cesarini, A.; Ciani, G.; Congedo, G.; Cruise, A. M.; Danzmann, K.; de Deus Silva, M.; De Rosa, R.; Diaz-Aguiló, M.; Di Fiore, L.; Diepholz, I.; Dixon, G.; Dolesi, R.; Dunbar, N.; Ferraioli, L.; Ferroni, V.; Fichter, W.; Fitzsimons, E. D.; Flatscher, R.; Freschi, M.; García Marín, A. F.; García Marirrodriga, C.; Gerndt, R.; Gesa, L.; Gibert, F.; Giardini, D.; Giusteri, R.; Guzmán, F.; Grado, A.; Grimani, C.; Grynagier, A.; Grzymisch, J.; Harrison, I.; Heinzel, G.; Hewitson, M.; Hollington, D.; Hoyland, D.; Hueller, M.; Inchauspé, H.; Jennrich, O.; Jetzer, P.; Johann, U.; Johlander, B.; Karnesis, N.; Kaune, B.; Korsakova, N.; Killow, C. J.; Lobo, J. A.; Lloro, I.; Liu, L.; López-Zaragoza, J. P.; Maarschalkerweerd, R.; Mance, D.; Martín, V.; Martin-Polo, L.; Martino, J.; Martin-Porqueras, F.; Madden, S.; Mateos, I.; McNamara, P. W.; Mendes, J.; Mendes, L.; Monsky, A.; Nicolodi, D.; Nofrarias, M.; Paczkowski, S.; Perreur-Lloyd, M.; Petiteau, A.; Pivato, P.; Plagnol, E.; Prat, P.; Ragnit, U.; Raïs, B.; Ramos-Castro, J.; Reiche, J.; Robertson, D. I.; Rozemeijer, H.; Rivas, F.; Russano, G.; Sanjuán, J.; Sarra, P.; Schleicher, A.; Shaul, D.; Slutsky, J.; Sopuerta, C. F.; Stanga, R.; Steier, F.; Sumner, T.; Texier, D.; Thorpe, J. I.; Trenkel, C.; Tröbs, M.; Tu, H. B.; Vetrugno, D.; Vitale, S.; Wand, V.; Wanner, G.; Ward, H.; Warren, C.; Wass, P. J.; Wealthy, D.; Weber, W. J.; Wissel, L.; Wittchen, A.; Zambotti, A.; Zanoni, C.; Ziegler, T.; Zweifel, P.

    2016-06-01

    We report the first results of the LISA Pathfinder in-flight experiment. The results demonstrate that two free-falling reference test masses, such as those needed for a space-based gravitational wave observatory like LISA, can be put in free fall with a relative acceleration noise with a square root of the power spectral density of 5.2 ±0.1 fm s-2/√{Hz } , or (0.54 ±0.01 ) ×10-15 g/√{Hz } , with g the standard gravity, for frequencies between 0.7 and 20 mHz. This value is lower than the LISA Pathfinder requirement by more than a factor 5 and within a factor 1.25 of the requirement for the LISA mission, and is compatible with Brownian noise from viscous damping due to the residual gas surrounding the test masses. Above 60 mHz the acceleration noise is dominated by interferometer displacement readout noise at a level of (34.8 ±0.3 ) fm /√{Hz } , about 2 orders of magnitude better than requirements. At f ≤0.5 mHz we observe a low-frequency tail that stays below 12 fm s-2/√{Hz } down to 0.1 mHz. This performance would allow for a space-based gravitational wave observatory with a sensitivity close to what was originally foreseen for LISA.

  19. LISA Pathfinder test-mass charging during galactic cosmic-ray flux short-term variations

    NASA Astrophysics Data System (ADS)

    Grimani, C.; Fabi, M.; Lobo, A.; Mateos, I.; Telloni, D.

    2015-02-01

    Metal free-floating test masses aboard the future interferometers devoted to gravitational wave detection in space are charged by galactic and solar cosmic rays with energies \\gt 100 MeV/n. This process represents one of the main sources of noise in the lowest frequency band (\\lt 10-3 Hz) of these experiments. We study here the charging of the LISA Pathfinder (LISA-PF) gold-platinum test masses due to galactic cosmic-ray (GCR) protons and helium nuclei with the Fluka Monte Carlo toolkit. Projections of the energy spectra of GCRs during the LISA-PF operations in 2015 are considered. This work was carried out on the basis of the solar activity level and solar polarity epoch expected for LISA-PF. The effects of GCR short-term variations are evaluated here for the first time. Classical Forbush decreases, GCR variations induced by the Sun rotation, and fluctuations in the LISA-PF frequency bandwidth are discussed.

  20. Changing Configurations of Adult Education in Transitional Times. Conference Proceedings of the Triennial European Research Conference of the European Society for Research on the Education of Adults (ESREA) (7th, Berlin, Germany, September 4-7, 2013)

    ERIC Educational Resources Information Center

    Käpplinger, Bernd, Ed.; Lichte, Nina, Ed.; Haberzeth, Erik, Ed.; Kulmus, Claudia, Ed.

    2014-01-01

    This book assembles over 50 papers from the 7th Triennial European Research Conference of the European Society for Research on the Education of Adults (ESREA), which was held from the 4th to the 7th of September 2013 at Humboldt-University in Berlin. The title of the conference was "Changing Configurations of Adult Education in Transitional…

  1. 7th EFIS Tatra Immunology Conference. Molecular determinants of T-cell immunity. 24-28 June 2006, High Tatra Mountains, Slovakia.

    PubMed

    Leishman, Andrew J

    2006-10-01

    This meeting was hosted by the European Federation of Immunological Societies celebrating its 7th meeting in the High Tatra Mountains of Slovakia on 24-28 June 2006. Entitled molecular determinants of T-cell immunity, the meeting covered a wide range of novel methods to regulate an unwanted immune response in autoimmunity and boost the immune system to combat viral infection and cancer.

  2. [First results of participation of the Czech Republic in the 7th Framework Programme, priority Health, in years 2007-2013].

    PubMed

    Kinkorová, Judita

    2013-01-01

    European Commission has announced the first preliminary results of participation in the 7th Framework Programme (FP7), priority Health. The overview presents the basic statistics regarding the participation of the Czech teams, universities, institutions, and small and medium size enterprises (SMEs) in FP7 projects. The aim of the article is to present the basic data on the projects with the Czech participation, the EU financial contribution for Czech teams and the main research topics.

  3. High Performance Proteomics: 7th HUPO Brain Proteome Project Workshop March 7-9, 2007 Wellcome Trust Conference Centre, Hinxton, UK.

    PubMed

    Hamacher, Michael; Stephan, Christian; Eisenacher, Martin; Lewczuk, Piotr; Wiltfang, Jens; Martens, Lennart; Vizcaíno, Juan Antonio; Kwon, Kyung-Hoon; Yoo, Jong Shin; Park, Young Mok; Beckers, Johannes; Horsch, Marion; de Angelis, Martin Hrabé; Cho, Zang-Hee; Apweiler, Rolf; Meyer, Helmut E

    2007-08-01

    The Wellcome Trust Conference Centre at Hinxton, UK, was the meeting place of the 7th HUPO Brain Proteome Project Workshop entitled "High Performance Proteomics". It started on Wednesday, March 7, 2007 with a steering committee meeting followed by a two days series of talks dealing with the standardization and handling of tissues, body fluids as well as of proteomics data. The presentation and accompanying vivid discussions created a picture of actual strategies and standards in recent proteomics.

  4. Advancements of the Lightweight Integrated Solar Array and Transceiver (LISA-T) Small Spacecraft System

    NASA Technical Reports Server (NTRS)

    Russell, Tiffany; Martinez, Armando; Boyd, Darren; SanSoucie, Michael; Farmer, Brandon; Schneider, Todd; Fabisinski, Leo; Johnson, Les; Carr, John A.

    2015-01-01

    This paper describes recent advancements of the Lightweight Integrated Solar Array and Transceiver (LISA-T) currently being developed at NASA's Marshall Space Flight Center. The LISA-T array comprises a launch stowed, orbit deployed structure on which thin-film photovoltaic (PV) and antenna devices are embedded. The system provides significant electrical power generation at low weights, high stowage efficiency, and without the need for solar tracking. Leveraging high-volume terrestrial-market PVs also gives the potential for lower array costs. LISA-T is addressing the power starvation epidemic currently seen by many small-scale satellites while also enabling the application of deployable antenna arrays. Herein, an overview of the system and its applications are presented alongside sub-system development progress and environmental testing plans/initial results.

  5. Advancements of the Lightweight Integrated Solar Array and Transceiver (LISA-T) Small Spacecraft System

    NASA Technical Reports Server (NTRS)

    Lockett, Tiffany Russell; Martinez, Armando; Boyd, Darren; SanSouice, Michael; Farmer, Brandon; Schneider, Todd; Laue, Greg; Fabisinski, Leo; Johnson, Les; Carr, John A.

    2015-01-01

    This paper describes recent advancements of the Lightweight Integrated Solar Array and Transceiver (LISA-T) currently being developed at NASA's Marshall Space Flight Center. The LISA-T array comprises a launch stowed, orbit deployed structure on which thin-film photovoltaic (PV) and antenna devices are embedded. The system provides significant electrical power generation at low weights, high stowage efficiency, and without the need for solar tracking. Leveraging high-volume terrestrial-market PVs also gives the potential for lower array costs. LISA-T is addressing the power starvation epidemic currently seen by many small-scale satellites while also enabling the application of deployable antenna arrays. Herein, an overview of the system and its applications are presented alongside sub-system development progress and environmental testing plans.

  6. Preliminary Optimal Orbit Design for the Laser Interferometer Space Antenna (LISA)

    NASA Technical Reports Server (NTRS)

    Hughes, Steven P.; Bauer, Frank H. (Technical Monitor)

    2002-01-01

    In this paper we present a preliminary optimal orbit analysis for the Laser Interferometer Space Antenna (LISA). LISA is a NASA/ESA mission to study gravitational waves and test predictions of general relativity. The nominal formation consists of three spacecraft in heliocentric orbits at 1 AU and trailing the Earth by twenty degrees. This configuration was chosen as a trade off to reduce the noise sources that will affect the instrument and to reduce the fuel to achieve the final orbit. We present equations for the nominal orbit design and discuss several different measures of performance for the LISA formation. All of the measures directly relate the formation dynamics to science performance. Also, constraints on the formation dynamics due to spacecraft and instrument limitations are discussed. Using the nominal solution as an initial guess, the formation is optimized using Sequential Quadratic Programming to maximize the performance while satisfying a set of nonlinear constraints. Results are presented for each of the performance measures.

  7. The case of Lisa and the assimilation model: the interrelatedness of problematic voices.

    PubMed

    Brinegar, Meredith Glick; Salvi, Lisa M; Stiles, William B

    2008-11-01

    This study examines Lisa, a successful case of emotion-focused therapy, using the assimilation model as a lens to view and understand her changes. The assimilation model construes problems as voices, or parts of the self, that are unwanted and kept separate from other voices in the community that constitute the self. Progress in therapy, then, is construed as increasing the assimilation or integration of problematic voices into the community. Lisa made significant progress assimilating two distinct but related voices, described as movement through the Assimilation of Problematic Experiences Sequence. In the course of the analysis, the case of Lisa also informed the assimilation model by raising issues concerning the interrelatedness of problems and the dynamic nature of assimilation in the context of a multivoiced self.

  8. A demonstration of arm-locking for LISA using the GRACE-FO Laser Ranging Instrument

    NASA Astrophysics Data System (ADS)

    Thorpe, Ira; McKenzie, Kirk; Sutton, Andrew

    2015-04-01

    The mitigation of laser frequency noise is a key challenge for the design of space-based interferometric gravitational wave detectors such as the Laser Interferometer Space Antenna (LISA) and its derivatives. Arm locking is novel technique of stabilizing the laser frequency using the LISA arms that has been studied through simulations and in the laboratory. The Laser Ranging Instrument (LRI) on the upcoming GRACE-FO geodesy mission provides an opportunity to perform an on-orbit demonstration of arm-locking in a configuration that is representative of LISA in many aspects. In this talk, I will describe a potential arm-locking experiment for GRACE-FO and present preliminary results from time-domain simulations being used to refine the proposed experiment design.

  9. Precessing supermassive black hole binaries and dark energy measurements with LISA

    SciTech Connect

    Stavridis, Adamantios; Arun, K. G.; Will, Clifford M.

    2009-09-15

    Spin induced precessional modulations of gravitational wave signals from supermassive black hole binaries can improve the estimation of luminosity distance to the source by space based gravitational wave missions like the Laser Interferometer Space Antenna (LISA). We study how this impacts the ability of LISA to do cosmology, specifically, to measure the dark energy equation of state (EOS) parameter w. Using the {lambda}CDM model of cosmology, we show that observations of precessing binaries with mass ratio 10 ratio 1 by LISA, combined with a redshift measurement, can improve the determination of w up to an order of magnitude with respect to the nonprecessing case depending on the total mass and the redshift.

  10. In-flight thermal experiments for LISA Pathfinder: Simulating temperature noise at the Inertial Sensors

    NASA Astrophysics Data System (ADS)

    Armano, M.; Audley, H.; Auger, G.; Baird, J.; Binetruy, P.; Born, M.; Bortoluzzi, D.; Brandt, N.; Bursi, A.; Caleno, M.; Cavalleri, A.; Cesarini, A.; Cruise, M.; Danzmann, K.; Diepholz, I.; Dolesi, R.; Dunbar, N.; Ferraioli, L.; Ferroni, V.; Fitzsimons, E.; Freschi, M.; Gallegos, J.; García Marirrodriga, C.; Gerndt, R.; Gesa, Ll; Gibert, F.; Giardini, D.; Giusteri, R.; Grimani, C.; Harrison, I.; Heinzel, G.; Hewitson, M.; Hollington, D.; Hueller, M.; Huesler, J.; Inchauspé, H.; Jennrich, O.; Jetzer, P.; Johlander, B.; Karnesis, N.; Kaune, B.; Korsakova, N.; Killow, C.; Lloro, I.; Maarschalkerweerd, R.; Madden, S.; Maghami, P.; Mance, D.; Martín, V.; Martin-Porqueras, F.; Mateos, I.; McNamara, P.; Mendes, J.; Mendes, L.; Moroni, A.; Nofrarias, M.; Paczkowski, S.; Perreur-Lloyd, M.; Petiteau, A.; Pivato, P.; Plagnol, E.; Prat, P.; Ragnit, U.; Ramos-Castro, J.; Reiche, J.; Romera Perez, J. A.; Robertson, D.; Rozemeijer, H.; Russano, G.; Sarra, P.; Schleicher, A.; Slutsky, J.; Sopuerta, C. F.; Sumner, T.; Texier, D.; Thorpe, J.; Trenkel, C.; Tu, H. B.; Vetrugno, D.; Vitale, S.; Wanner, G.; Ward, H.; Waschke, S.; Wass, P.; Wealthy, D.; Wen, S.; Weber, W.; Wittchen, A.; Zanoni, C.; Ziegler, T.; Zweifel, P.

    2015-04-01

    Thermal Diagnostics experiments to be carried out on board LISA Pathfinder (LPF) will yield a detailed characterisation of how temperature fluctuations affect the LTP (LISA Technology Package) instrument performance, a crucial information for future space based gravitational wave detectors as the proposed eLISA. Amongst them, the study of temperature gradient fluctuations around the test masses of the Inertial Sensors will provide as well information regarding the contribution of the Brownian noise, which is expected to limit the LTP sensitivity at frequencies close to 1 mHz during some LTP experiments. In this paper we report on how these kind of Thermal Diagnostics experiments were simulated in the last LPF Simulation Campaign (November, 2013) involving all the LPF Data Analysis team and using an end-to-end simulator of the whole spacecraft. Such simulation campaign was conducted under the framework of the preparation for LPF operations.

  11. In-flight thermal experiments for LISA Pathfinder: Simulating temperature noise at the Inertial Sensors

    NASA Astrophysics Data System (ADS)

    Gibert, F.; Nofrarias, M.; Armano, M.; Audley, H.; Auger, G.; Baird, J.; Binetruy, P.; Born, M.; Bortoluzzi, D.; Brandt, N.; Bursi, A.; Caleno, M.; Cavalleri, A.; Cesarini, A.; Cruise, M.; Danzmann, K.; Diepholz, I.; Dolesi, R.; Dunbar, N.; Ferraioli, L.; Ferroni, V.; Fitzsimons, E.; Freschi, M.; Gallegos, J.; García Marirrodriga, C.; Gerndt, R.; Gesa, Ll; Giardini, D.; Giusteri, R.; Grimani, C.; Harrison, I.; Heinzel, G.; Hewitson, M.; Hollington, D.; Hueller, M.; Huesler, J.; Inchauspé, H.; Jennrich, O.; Jetzer, P.; Johlander, B.; Karnesis, N.; Kaune, B.; Korsakova, N.; Killow, C.; Lloro, I.; Maarschalkerweerd, R.; Madden, S.; Maghami, P.; Mance, D.; Martín, V.; Martin-Porqueras, F.; Mateos, I.; McNamara, P.; Mendes, J.; Mendes, L.; Moroni, A.; Paczkowski, S.; Perreur-Lloyd, M.; Petiteau, A.; Pivato, P.; Plagnol, E.; Prat, P.; Ragnit, U.; Ramos-Castro, J.; Reiche, J.; Romera Perez, J. A.; Robertson, D.; Rozemeijer, H.; Russano, G.; Sarra, P.; Schleicher, A.; Slutsky, J.; Sopuerta, C. F.; Sumner, T.; Texier, D.; Thorpe, J.; Trenkel, C.; Tu, H. B.; Vetrugno, D.; Vitale, S.; Wanner, G.; Ward, H.; Waschke, S.; Wass, P.; Wealthy, D.; Wen, S.; Weber, W.; Wittchen, A.; Zanoni, C.; Ziegler, T.; Zweifel, P.

    2015-05-01

    Thermal Diagnostics experiments to be carried out on board LISA Pathfinder (LPF) will yield a detailed characterisation of how temperature fluctuations affect the LTP (LISA Technology Package) instrument performance, a crucial information for future space based gravitational wave detectors as the proposed eLISA. Amongst them, the study of temperature gradient fluctuations around the test masses of the Inertial Sensors will provide as well information regarding the contribution of the Brownian noise, which is expected to limit the LTP sensitivity at frequencies close to 1 mHz during some LTP experiments. In this paper we report on how these kind of Thermal Diagnostics experiments were simulated in the last LPF Simulation Campaign (November, 2013) involving all the LPF Data Analysis team and using an end-to-end simulator of the whole spacecraft. Such simulation campaign was conducted under the framework of the preparation for LPF operations.

  12. Magnetic polarization effects of temperature sensors and heaters in LISA Pathfinder.

    PubMed

    Sanjuán, J; Lobo, A; Nofrarias, M; Mateos, N; Xirgu, X; Cañizares, P; Ramos-Castro, J

    2008-08-01

    Temperature sensors and heaters belong in the diagnostics subsystem of the LISA Technology Package (LTP) on board LISA Pathfinder, the technology demonstrator for LISA. A number of these diagnostics items are placed at short distances from the LTP proof masses and are negative temperature coefficient (NTC) thermistors. By design, these devices have tiny amounts of ferromagnetic materials, which therefore constitute a potential source of disturbance to the performance of the LTP. In this paper we report on detailed magnetic characterization of the NTCs and use the data to evaluate their impact on the acceleration noise budget of the LTP. The effect is seen to be small if the NTCs are submitted to a demagnetization process before they are attached. Remagnetization is unlikely, as rather strong fields (approximately millitesla) are required to produce enough NTC magnetic polarization.

  13. Metastatic lymph node ratio, 6th or 7th AJCC edition: witch is the best lymph node classification for esophageal cancer? Prognosis factor analysis in 487 patients

    PubMed Central

    CORAL, Roberto V.; BIGOLIN, André V.; CORAL, Roberto P.; HARTMANN, Antonio; DRANKA, Carolina; ROEHE, Adriana V.

    2015-01-01

    Background The esophageal cancer is one of the most common and aggressive worldwide. Recently, the AJCC changed the staging system, considering, among others, the important role of the lymph node metastasis on the prognosis. Aim To discuss the applicability of different forms of lymph node staging in a western surgical center. Methods Four hundred eighty seven patients with esophageal cancer were enrolled. Three staging systems were evaluated, the 6th and the 7th AJCC editions and the Lymph Node Metastatic Ratio. Results The majority of the cases were squamous cell carcinoma. The mean lymph node sample was eight. Considering the survival, there was no significant difference between the patients when they were classified by the 7th AJCC edition. Analysis of the Lymph Node Metastatic Ratio, just on the group of patients with 0 to 25%, has shown significant difference (p=0,01). The 6th AJCC edition shows the major significant difference between among the classifications evaluated. Conclusion In this specific population, the 7th AJCC edition for esophageal cancer was not able to find differences in survival when just the lymph node analysis was considered. PMID:26176242

  14. The LTP Experiment on LISA Pathfinder: Operational Definition of TT Gauge in Space

    NASA Astrophysics Data System (ADS)

    Armano, Michele

    2011-10-01

    The European Space Agency (ESA) and the National Aeronautics and Space Administration (NASA) are planning the Laser Interferometer Space Antenna (LISA) mission in order to detect GW. The need of accurate testing of free-fall and knowledge of noise in a space environment similar to LISA's is considered mandatory a pre-phase for the project. Therefore the LISA Pathfinder mission has been designed by ESA to fly the LISA Technology Package (LTP), aiming at testing free-fall by measuring the residual acceleration between two test-bodies in the dynamical scheme we address as "drag-free". The spectral map of the residual acceleration as function of frequency will convey information on the local noise level, thus producing a picture of the environmental working conditions for LISA itself. The thesis contains abundant material on the problem of compensating static gravity, the development of a theory of orthogonalization of reference and cross-talk for the LTP experiment. The construction of the laser detection procedure starting from GR and differential geometry arguments is carried on. Effort was put in pointing out the physical motivations for the choices made in several other papers by the author and colleagues. In this perspective the thesis is meant as a summary tool for the LTP collaboration. In the second part of the thesis we summarize our contributions for a measurement of G onboard LTP and review on possible tests of fundamental physics the mission might embody. A wide part of the thesis is now part of the LTP Operation Master Plan, describing the real science and operations onboard LISA Pathfinder. This thesis was defended on September 26th, 2006 at the University of Como, Italy.

  15. LISA technologies in new light: exploring alternatives for charge management and optical bench construction

    NASA Astrophysics Data System (ADS)

    Ciani, Giacomo; Chilton, Andrew; Olatunde, Taiwo; Apple, Stephen; Conklin, John W.; Mueller, Guido

    2015-08-01

    A LISA-like gravitational wave observatory is the choice candidate for ESA's L3 large mission scheduled to launch in 2034. The LISA Test Package (LTP) mission will launch later this year and test many critical technologies needed for such an observatory, among which are picometer interferometry in space and UV charge management of the Test Mass (TM). The design of these subsystems has been frozen many years ago during the final formulation of the LTP mission; since then, the LISA mission concept has evolved and new technologies have become available, making it possible to re-think the way these subsystem are implemented. With the final formulation of the L3 mission still years in the future and the LTP results expected in about one year, now is an ideal time look for areas of possible improvement and explore alternative implementations that can enhance performance, reduce costs or mitigate risks.Recently developed UV LED are lighter, cheaper and more powerful than traditional mercury lamps; in addition, their fast response time can be used to implement AC discharge techniques that can save even more space and power, and provide a more precise control of the charge.The most recent iteration of the mission baseline design allows for eliminating some of the optical components initially deemed essential; paired with the use of polarization multiplexing, this permits a redesign of the optical bench that simplifies the layout and enables a modular approach to machining and assembly, thus reducing the risks and costs associated with the current monolithic design without compromising the picometer stability of the optical path.Leveraging on extensive previous experience with LISA interferometry and the availability of a torsion pendulum-based LISA test-bed, the University of Florida LISA group is working at developing, demonstrating and optimizing both these technologies. I will describe the most recent advancements and results.

  16. PREFACE: Proceedings of the 7th Edoardo Amaldi Conference on Gravitational Waves (Amaldi7), Sydney Convention and Exhibition Centre, Darling Harbour, Sydney, Australia, 8 14 July 2007

    NASA Astrophysics Data System (ADS)

    Scott, Susan M.; McClelland, David E.

    2008-07-01

    At GR17 in Dublin in 2004, it was decided to hold GR18 in Sydney in 2007. Every six years, the GR conference (held every three years) and Amaldi meeting (held every two years) occur in the same year around July. This was to be the case in 2007. By mutual agreement of the International Society on General Relativity and Gravitation (ISGRG), which oversees the GR conferences and The Gravitational Wave International Committee (GWIC), which oversees the Amaldi meetings, it was decided to hold these two important conferences concurrently, for the first time, at the same venue, namely Sydney. At a time when the gravitational wave community was beginning to explore the possibility of searches to probe various aspects of the theory, the vision was to bring that community together with the community of gravitational theorists in order to better appreciate the work being done by both parties and to explore possibilities for future research using the mutual expertise. The logistics of running two such large meetings concurrently were considerable. The format agreed upon by the ISGRG and GWIC was the following: common plenary sessions in the mornings from Monday to Friday; six parallel GR workshop sessions and an Amaldi session each afternoon from Monday to Friday (except Wednesday); a combined poster session on Wednesday; a full day of Amaldi sessions on the final day (Saturday). The scientific programme for GR18 was overseen by a Scientific Organising Committee established by the ISGRG and chaired by Professor Sathyaprakash. The scientific programme for Amaldi7 was overseen by GWIC chaired by Professor Cerdonio. One of the highlights of the conferences was the breadth and quality of the plenary programme put together by the scientific committees. Not only did these talks give an excellent snapshot of the entire field at this time, but they also explored the interfaces with other related fields, which proved of special interest to participants. We were given superb overviews

  17. Doing Science with eLISA: Astrophysics and Cosmology in the Millihertz Regime

    NASA Technical Reports Server (NTRS)

    Amaro, Seoane, Pau; Aoudia, Sofiane; Babak, Stanislav; Binetruy, Pierre; Berti, Amanuele; Bohe, Alejandro; Caprini, Chiara; Colpi, Monica; Cornish, Neil J.; Danzmann, Karsten; Dufaux, Jean-Francois; Gair, Jonathan; Jennrich, Oliver; Jetzer, Philippe; Klein, Antoine; Lang, Ryan N.; Lobo, Albsrto; Littenberg, Tyson; McWilliams, Sean T.; Nelemans, Gijs; Petiteau, Antoine; Porter, Edward K.; Schutz, Bernard F.; Stebbins, Robin; Vallisneri, Michele

    2012-01-01

    This document introduces the exciting and fundamentally new science and astronomy that the European New Gravitational Wave Observatory (NGO) mission (derived from the previous LISA proposal) will deliver. The mission (which we will refer to by its informal name eLISA ) will survey for the first time the low-frequency gravitational wave band (about 0.1 mHz to 1 Hz), with sufficient sensitivity to detect interesting individual astrophysical sources out to z = 15. The measurements described here will address the basic scientific goals that have been captured in ESA s New Gravitational Wave Observatory Science Requirements Document ; they are presented here so that the wider scientific community can have access to them. The eLISA mission will discover and study a variety of cosmic events and systems with high sensitivity: coalescences of massive black holes binaries, brought together by galaxy mergers; mergers of earlier, less-massive black holes during the epoch of hierarchical galaxy and black-hole growth; stellar-mass black holes and compact stars in orbits just skimming the horizons of massive black holes in galactic nuclei of the present era; extremely compact white dwarf binaries in our Galaxy, a rich source of information about binary evolution and about future Type Ia supernovae; and possibly most interesting of all, the uncertain and unpredicted sources, for example relics of inflation and of the symmetry-breaking epoch directly after the Big Bang. eLISA s measurements will allow detailed studies of these signals with high signal-to-noise ratio, addressing most of the key scientific questions raised by ESA s Cosmic Vision programme in the areas of astrophysics and cosmology. They will also provide stringent tests of general relativity in the strong-field dynamical regime, which cannot be probed in any other way. This document not only describes the science but also gives an overview on the mission design and orbits. LISA s heritage in the eLISA design will be

  18. Some Progress In The Development Of An Optical Readout System For The LISA Gravitational Reference Sensor

    NASA Astrophysics Data System (ADS)

    Acernese, Fausto; De Rosa, Rosario; Di Fiore, Luciano; Garufi, Fabio; La Rana, Adele; Milano, Leopoldo

    2006-11-01

    In this paper, we report on the progress in the development of an optical read-out (ORO) system for the inertial sensor of the LISA gravitational wave antenna. The device is based on optical levers and position sensors and is intended to be integrated in the present baseline design for the LISA inertial sensor, which is based on capacitive readout of the test mass position. In particular, we report some improved measurement of the sensitivity of this device, performed with a bench-top rigid set-up and tests on a real scale prototype.

  19. The Mock LISA Data Challenge Round 3: New and Improved Sources

    NASA Technical Reports Server (NTRS)

    Baker, John

    2008-01-01

    The Mock LISA Data Challenges are a program to demonstrate and encourage the development of data-analysis capabilities for LISA. Each round of challenges consists of several data sets containing simulated instrument noise and gravitational waves from sources of undisclosed parameters. Participants are asked to analyze the data sets and report the maximum information they can infer about the source parameters. The challenges are being released in rounds of increasing complexity and realism. Challenge 3. currently in progress, brings new source classes, now including cosmic-string cusps and primordial stochastic backgrounds, and more realistic signal models for supermassive black-hole inspirals and galactic double white dwarf binaries.

  20. Observing the Final Moments of Massive Black Hole Mergers with LISA.

    NASA Technical Reports Server (NTRS)

    Baker, John

    2006-01-01

    Mergers of binary black hole systems are one of the strongest sources of gravitational radiation expected to be observed by LISA. Recent advances in modeling the final merger and ringdown of comparable-mass systems, particularly via numerical relativity simulations, are dramatically expanding our understanding of these systems and the radiation they generate. We summarize recent modeling results, highlighting the work of Goddard s numerical relativity group, and apply this emerging knowledge to the problem of observing the final moments of binary black hole mergers with LISA.

  1. Development of an Optical Read-Out System for the LISA/NGO Gravitational Reference Sensor: A Status Report

    NASA Astrophysics Data System (ADS)

    Di Fiore, L.; De Rosa, R.; Garufi, F.; Grado, A.; Milano, L.; Spagnuolo, V.; Russano, G.

    2013-01-01

    The LISA group in Napoli is working on the development of an Optical Read-Out (ORO) system, based on optical levers and position sensitive detectors, for the LISA gravitational reference sensor. ORO is not meant as an alternative, but as an addition, to capacitive readout, that is the reference solution for LISA/NGO and will be tested on flight by LISA-Pathfinder. The main goal is the introduction of some redundancy with consequent mission risk mitigation. Furthermore, the ORO system is more sensitive than the capacitive one and its usage would allow a significant relaxation of the specifications on cross-couplings in the drag free control loops. The reliability of the proposed ORO device and the fulfilment of the sensitivity requirements have been already demonstrated in bench-top measurements and tests with the four mass torsion pendulum developed in Trento as a ground testing facility for LISA-Pathfinder and LISA hardware. In this paper we report on the present status of this activity presenting the last results and perspectives on some relevant aspects. 1) System design, measured sensitivity and noise characterization. 2) Possible layouts for integration in LISA/NGO and bench-top tests on real scale prototypes. 3) Search for space compatible components and preliminary tests. We will also discuss next steps in view of a possible application in LISA/NGO.

  2. Sky Localization of Complete Inspiral-Merger-Ringdown Signals for Nonspinning Black Hole Binaries with LISA

    NASA Technical Reports Server (NTRS)

    McWilliams, Sean T.; Lang, Ryan N.; Baker, John G.; Thorpe, James Ira

    2011-01-01

    We investigate the capability of LISA to measure the sky position of equal-mass, nonspinning black hole binaries, including for the first time the entire inspiral-merger-ringdown signal, the effect of the LISA orbits, and the complete three-channel LISA response. For an ensemble of systems near the peak of LISA's sensitivity band, with total rest mass of 2 x l0(exp 6) Stellar Mass at a redshift of z = 1 with random orientations and sky positions, we find median sky localization errors of approximately approx. 3 arcminutes. This is comparable to the field of view of powerful electromagnetic telescopes, such as the James Webb Space Telescope, that could be used to search for electromagnetic signals associated with merging black holes. We investigate the way in which parameter errors decrease with measurement time, focusing specifically on the additional information provided during the merger-ringdown segment of the signal. We find that this information improves all parameter estimates directly, rather than through diminishing correlations with any subset of well-determined parameters.

  3. Continuous Glucose Monitoring Enables the Detection of Losses in Infusion Set Actuation (LISAs)

    PubMed Central

    Howsmon, Daniel P.; Cameron, Faye; Baysal, Nihat; Ly, Trang T.; Forlenza, Gregory P.; Maahs, David M.; Buckingham, Bruce A.; Hahn, Juergen; Bequette, B. Wayne

    2017-01-01

    Reliable continuous glucose monitoring (CGM) enables a variety of advanced technology for the treatment of type 1 diabetes. In addition to artificial pancreas algorithms that use CGM to automate continuous subcutaneous insulin infusion (CSII), CGM can also inform fault detection algorithms that alert patients to problems in CGM or CSII. Losses in infusion set actuation (LISAs) can adversely affect clinical outcomes, resulting in hyperglycemia due to impaired insulin delivery. Prolonged hyperglycemia may lead to diabetic ketoacidosis—a serious metabolic complication in type 1 diabetes. Therefore, an algorithm for the detection of LISAs based on CGM and CSII signals was developed to improve patient safety. The LISA detection algorithm is trained retrospectively on data from 62 infusion set insertions from 20 patients. The algorithm collects glucose and insulin data, and computes relevant fault metrics over two different sliding windows; an alarm sounds when these fault metrics are exceeded. With the chosen algorithm parameters, the LISA detection strategy achieved a sensitivity of 71.8% and issued 0.28 false positives per day on the training data. Validation on two independent data sets confirmed that similar performance is seen on data that was not used for training. The developed algorithm is able to effectively alert patients to possible infusion set failures in open-loop scenarios, with limited evidence of its extension to closed-loop scenarios. PMID:28098839

  4. Neural network interpolation of the magnetic field for the LISA Pathfinder Diagnostics Subsystem

    NASA Astrophysics Data System (ADS)

    Diaz-Aguilo, Marc; Lobo, Alberto; García-Berro, Enrique

    2011-05-01

    LISA Pathfinder is a science and technology demonstrator of the European Space Agency within the framework of its LISA mission, which aims to be the first space-borne gravitational wave observatory. The payload of LISA Pathfinder is the so-called LISA Technology Package, which is designed to measure relative accelerations between two test masses in nominal free fall. Its disturbances are monitored and dealt by the diagnostics subsystem. This subsystem consists of several modules, and one of these is the magnetic diagnostics system, which includes a set of four tri-axial fluxgate magnetometers, intended to measure with high precision the magnetic field at the positions of the test masses. However, since the magnetometers are located far from the positions of the test masses, the magnetic field at their positions must be interpolated. It has been recently shown that because there are not enough magnetic channels, classical interpolation methods fail to derive reliable measurements at the positions of the test masses, while neural network interpolation can provide the required measurements at the desired accuracy. In this paper we expand these studies and we assess the reliability and robustness of the neural network interpolation scheme for variations of the locations and possible offsets of the magnetometers, as well as for changes in environmental conditions. We find that neural networks are robust enough to derive accurate measurements of the magnetic field at the positions of the test masses in most circumstances.

  5. Accelerated prospective parameter estimation for observing black hole mergers with LISA

    NASA Astrophysics Data System (ADS)

    Baker, John; Marsat, Sylvain; Graff, Philip

    2016-03-01

    LISA, a candidate for the European Space Agency's planned L3 gravitational wave mission, is expected to provide tremendous capabilities in observing merging black holes out to very high redshifts with much higher signal-to-noise ratios than are likely with ground-based observations. Understanding precisely how well we may be able to measure these systems requires detailed Bayesian analysis with the best available theoretical waveform predictions and a full treatment of LISA's instrumental response. Highly accurate representations of general relativity's signal predictions, such as those of the Effective-One-Body formalism, are becoming available but these are too slow to compute directly. We address the practical challenge of computing the signals and response both accurately and quickly with frequency-domain reduced order signal models and apt approximation techniques for LISA's instrumental response to achieve millisecond likelihood evaluations. We apply these techniques to study of the impact of higher-harmonics in LISA observations of non-spinning mergers. Supported by NASA Grant 11-ATP-046.

  6. Continuous Glucose Monitoring Enables the Detection of Losses in Infusion Set Actuation (LISAs).

    PubMed

    Howsmon, Daniel P; Cameron, Faye; Baysal, Nihat; Ly, Trang T; Forlenza, Gregory P; Maahs, David M; Buckingham, Bruce A; Hahn, Juergen; Bequette, B Wayne

    2017-01-15

    Reliable continuous glucose monitoring (CGM) enables a variety of advanced technology for the treatment of type 1 diabetes. In addition to artificial pancreas algorithms that use CGM to automate continuous subcutaneous insulin infusion (CSII), CGM can also inform fault detection algorithms that alert patients to problems in CGM or CSII. Losses in infusion set actuation (LISAs) can adversely affect clinical outcomes, resulting in hyperglycemia due to impaired insulin delivery. Prolonged hyperglycemia may lead to diabetic ketoacidosis-a serious metabolic complication in type 1 diabetes. Therefore, an algorithm for the detection of LISAs based on CGM and CSII signals was developed to improve patient safety. The LISA detection algorithm is trained retrospectively on data from 62 infusion set insertions from 20 patients. The algorithm collects glucose and insulin data, and computes relevant fault metrics over two different sliding windows; an alarm sounds when these fault metrics are exceeded. With the chosen algorithm parameters, the LISA detection strategy achieved a sensitivity of 71.8% and issued 0.28 false positives per day on the training data. Validation on two independent data sets confirmed that similar performance is seen on data that was not used for training. The developed algorithm is able to effectively alert patients to possible infusion set failures in open-loop scenarios, with limited evidence of its extension to closed-loop scenarios.

  7. Heterodyne stabilization as a possible laser frequency stabilization technique for LISA

    NASA Astrophysics Data System (ADS)

    Eichholz, Johannes

    The Laser Interferometer Space Antenna is a joint NASA/ESA mission aimed at the detection of gravitational wave radiation in the frequency range from 30 uHz to 0.1 Hz. LISA uses a modified Michelson interferometer setup consisting of three identical spacecraft, arranged in an equilateral triangular constellation. It measures the differential length changes of the 5 · 109 m long interferometer arms between free-floating proof masses housed within each spacecraft. Laser pre-stabilization is required in conjunction with Time-Delay Interferometry data post-processing to monitor the armlength changes with picometer precision. A modulation/demodulation technique to stabilize the frequency of the lasers to an optical reference cavity has been proposed for a long time, but it requires several additional optical components and would need to be built as a separate system. Using a different sensing tech-nique, heterodyne interferometry, we propose a modified stabilization scheme, which similarly transfers the stability of an optical reference cavity to the laser frequency. It only uses com-ponents that are already available in the LISA assembly and can easily be integrated into the optical bench design. A similar stabilization scheme is going to be used in LISA Pathfinder. We will discuss this technique in detail and present initial experimental results, as well as predicted performances on the LISA bench.

  8. Modulation of LISA free-fall orbits due to the Earth-Moon system

    NASA Astrophysics Data System (ADS)

    Cerdonio, Massimo; De Marchi, Fabrizio; De Pietri, Roberto; Jetzer, Philippe; Marzari, Francesco; Mazzolo, Giulio; Ortolan, Antonello; Sereno, Mauro

    2010-08-01

    We calculate the effect of the Earth-Moon (EM) system on the free-fall motion of LISA test masses. We show that the periodic gravitational pulling of the EM system induces a resonance with fundamental frequency 1 yr-1 and a series of periodic perturbations with frequencies equal to integer harmonics of the synodic month (sime 3.92 × 10-7 Hz). We then evaluate the effects of these perturbations (up to the 6th harmonics) on the relative motions between each test mass couple, finding that they range between 3 mm and 10 pm for the 2nd and 6th harmonic, respectively. If we take the LISA sensitivity curve, as extrapolated down to 10-6 Hz in Bender (2003 Class. Quantum Grav. 20 301-10), we obtain that a few harmonics of the EM system can be detected in the Doppler data collected by the LISA space mission. This suggests that the EM system gravitational near field could provide an additional crosscheck to the calibration of LISA, as extended to such low frequencies.

  9. Science with the space-based interferometer eLISA: Supermassive black hole binaries

    NASA Astrophysics Data System (ADS)

    Klein, Antoine; Barausse, Enrico; Sesana, Alberto; Petiteau, Antoine; Berti, Emanuele; Babak, Stanislav; Gair, Jonathan; Aoudia, Sofiane; Hinder, Ian; Ohme, Frank; Wardell, Barry

    2016-01-01

    We compare the science capabilities of different eLISA mission designs, including four-link (two-arm) and six-link (three-arm) configurations with different arm lengths, low-frequency noise sensitivities and mission durations. For each of these configurations we consider a few representative massive black hole formation scenarios. These scenarios are chosen to explore two physical mechanisms that greatly affect eLISA rates, namely (i) black hole seeding, and (ii) the delays between the merger of two galaxies and the merger of the black holes hosted by those galaxies. We assess the eLISA parameter estimation accuracy using a Fisher matrix analysis with spin-precessing, inspiral-only waveforms. We quantify the information present in the merger and ringdown by rescaling the inspiral-only Fisher matrix estimates using the signal-to-noise ratio from nonprecessing inspiral-merger-ringdown phenomenological waveforms, and from a reduced set of precessing numerical relativity/post-Newtonian hybrid waveforms. We find that all of the eLISA configurations considered in our study should detect some massive black hole binaries. However, configurations with six links and better low-frequency noise will provide much more information on the origin of black holes at high redshifts and on their accretion history, and they may allow the identification of electromagnetic counterparts to massive black hole mergers.

  10. Laser Noise Stabilization, Processing, And Extraction Simulations For The Lisa Mission At The University Of Florida.

    NASA Astrophysics Data System (ADS)

    Yu, Yinan; Mitryk, S.; Sweeney, D.; Spector, A.; Eichholz, J.; Donelan, D.; Preston, A.; Munoz, J. S.; Azer, S.; Tanner, D.; Mueller, G.

    2011-05-01

    The Laser Interferometer Space Antenna (LISA) Mission will strive to measure gravitational radiation in the frequency range from 1 Hz to 0.1 mHz from black hole mergers and other compact objects. Three spacecraft (SC) in a nearly equilateral triangular formation with an arm-length of 5.0 ± 0.025 Gm form the space-based interferometer. Differential length changes between free-floating proof-masses will be measured to an accuracy of 40 pm/√Hz using one-way laser phase measurements between lasers on adjacent SC. Accurately reconstructing the differential arm-length and extracting the gravitational wave signals from the photo-detector beatnotes depends on the performance of the laser pre-stabilization system, the ability of time-delay interferometry (TDI) to cancel the additional laser phase noise, the accuracy of the distance-ranging measurement between the SC, the sensitivity of the laser beatnote phase measurement, and the quality of the inter-SC clock transfers. The University of Florida Laser Interferometry Simulator (UFLIS) emulates the LISA interferometry using LISA-like laser noise sources, electronic replications of inter-SC laser phase delays, and µcycle/√Hz phase measurements of MHz-frequency laser beat-notes to test LISA interferometry. This work is supported by NASA Grant #NNX08AG75G.

  11. CFRP Dimensional Stability Investigations for Use on the LISA Mission Telescope

    NASA Technical Reports Server (NTRS)

    Sanjuan, J.; Korytov, D.; Spector, A.; Mueller, G.; Preston, A.; Livas, J.; Freise, A.; Dixon, G.

    2011-01-01

    The Laser Interferometer Space Antenna (LISA) is a mission designed to detect low frequency gravitational-waves. In order for LISA to succeed in its goal of direct measurement of gravitational waves, many subsystems must work together to measure the distance between proof masses on adjacent spacecraft. One such subsystem, the telescope, plays a critical role as it is the laser transmission and reception link between spacecraft. Not only must the material that makes up the telescope support structure be strong, stiff and light, but it must have a dimensional stability of better than 1 pm Hz(exp -1/2) at 3 mHz and the distance between the primary and the secondary mirrors must change by less than 2.5 micron over the mission lifetime. CFRP is the current baseline materiaL however, it has not been tested to the pico-meter level as required by the LISA mission. In this paper we present dimensional stability results, outgassing effects occurring in the cavity and discuss its feasibility for use as the telescope spacer for the LISA spacecraft.

  12. LISA: the Italian CRG beamline for x-ray Absorption Spectroscopy at ESRF

    NASA Astrophysics Data System (ADS)

    d'Acapito, F.; Trapananti, A.; Puri, A.

    2016-05-01

    LISA is the acronym of Linea Italiana per la Spettroscopia di Assorbimento di raggi X (Italian beamline for X-ray Absorption Spectroscopy) and is the upgrade of the former GILDA beamline installed on the BM08 bending magnet port of European Synchrotron Radiation Facility (ESRF). Within this contribution a full description of the project is provided.

  13. LISA: a java API for performing simulations of trajectories for all types of balloons

    NASA Astrophysics Data System (ADS)

    Conessa, Huguette

    2016-07-01

    LISA (LIbrarie de Simulation pour les Aerostats) is a java API for performing simulations of trajectories for all types of balloons (Zero Pressure Balloons, Pressurized Balloons, Infrared Montgolfier), and for all phases of flight (ascent, ceiling, descent). This library has for goals to establish a reliable repository of Balloons flight physics models, to capitalize developments and control models used in different tools. It is already used for flight physics study software in CNES, to understand and reproduce the behavior of balloons, observed during real flights. It will be used operationally for the ground segment of the STRATEOLE2 mission. It was developed with quality rules of "critical software." It is based on fundamental generic concepts, linking the simulation state variables to interchangeable calculation models. Each LISA model defines how to calculate a consistent set of state variables combining validity checks. To perform a simulation for a type of balloon and a phase of flight, it is necessary to select or create a macro-model that is to say, a consistent set of models to choose from among those offered by LISA, defining the behavior of the environment and the balloon. The purpose of this presentation is to introduce the main concepts of LISA, and the new perspectives offered by this library.

  14. A Strategy to Characterize the LISA-Pathfinder Cold Gas Thruster System

    NASA Astrophysics Data System (ADS)

    Armano, M.; Audley, H.; Auger, G.; Baird, J.; Binetruy, P.; Born, M.; Bortoluzzi, D.; Brandt, N.; Bursi, A.; Caleno, M.; Cavalleri, A.; Cesarini, A.; Cruise, M.; Danzmann, K.; Diepholz, I.; Dolesi, R.; Dunbar, N.; Ferraioli, L.; Ferroni, V.; Fitzsimons, E.; Freschi, M.; Gallegos, J.; Garcia Marirrodriga, C.; Gerndt, R.; Gesa, L. I.; Gibert, F.; Giardini, D.; Giusteri, R.; Grimani, C.; Harrison, I.; Heinzel, G.; Hewitson, M.; Hollington, D.; Hueller, M.; Huesler, J.; Inchauspé, H.; Jennrich, O.; Jetzer, P.; Johlander, B.; Karnesis, N.; Kaune, B.; Korsakova, N.; Killow, C.; Lloro, I.; Maarschalkerweerd, R.; Madden, S.; Mance, D.; Martin, V.; Martin-Porqueras, F.; Mateos, I.; McNamara, P.; Mendes, J.; Mendes, L.; Moroni, A.; Nofrarias, M.; Paczkowski, S.; Perreur-Lloyd, M.; Petiteau, A.; Pivato, P.; Plagnol, E.; Prat, P.; Ragnit, U.; Ramos-Castro, J.; Reiche, J.; Romera Perez, J. A.; Robertson, D.; Rozemeijer, H.; Russano, G.; Sarra, P.; Schleicher, A.; Slutsky, J.; Sopuerta, C. F.; Sumner, T.; Texier, D.; Thorpe, J.; Trenkel, C.; Tu, H. B.; Vitale, S.; Wanner, G.; Ward, H.; Waschke, S.; Wass, P.; Wealthy, D.; Wen, S.; Weber, W.; Wittchen, A.; Zanoni, C.; Ziegler, T.; Zweifel, P.

    2015-05-01

    The cold gas micro-propulsion system that will be used during the LISA-Pathfinder mission will be one of the most important component used to ensure the "free-fall" of the enclosed test masses. In this paper we present a possible strategy to characterize the effective direction and amplitude gain of each of the 6 thrusters of this system.

  15. Interpolation of the magnetic field at the test masses in eLISA

    NASA Astrophysics Data System (ADS)

    Mateos, I.; Díaz-Aguiló, M.; Ramos-Castro, J.; García-Berro, E.; Lobo, A.

    2015-08-01

    A feasible design for a magnetic diagnostics subsystem for eLISA will be based on that of its precursor mission, LISA Pathfinder. Previous experience indicates that magnetic field estimation at the positions of the test masses has certain complications. This is due to two reasons. The first is that magnetometers usually back-act due to their measurement principles (i.e., they also create their own magnetic fields), while the second is that the sensors selected for LISA Pathfinder have a large size, which conflicts with space resolution and with the possibility of having a sufficient number of them to properly map the magnetic field around the test masses. However, high-sensitivity and small-sized sensors that significantly mitigate the two aforementioned limitations exist, and have been proposed to overcome these problems. Thus, these sensors will be likely selected for the magnetic diagnostics subsystem of eLISA. Here we perform a quantitative analysis of the new magnetic subsystem, as it is currently conceived, and assess the feasibility of selecting these sensors in the final configuration of the magnetic diagnostic subsystem.

  16. Evaluation of new technologies for the LISA gravitational reference sensor using the UF torsion pendulum

    NASA Astrophysics Data System (ADS)

    Conklin, John; Chilton, Andrew; Olatunde, Taiwo; Apple, Stephen; Aitken, Michael; Ciani, Giacomo; Mueller, Guido

    2016-01-01

    The Laser Interferometer Space Antenna (LISA) is the most mature concept for detecting gravitational waves from space. The LISA design has been studied for more than 20 years as a joint effort between NASA and the European Space Agency. LISA consists of three Sun-orbiting spacecraft that form an equilateral triangle, with each side measuring 1-5 million kilometers in length. Each spacecraft houses two free-floating test masses, which are protected from all disturbing forces so that they follow pure geodesics. A single test mass together with its protective housing and associated components is referred to as a gravitational reference sensor. A drag-free control system is supplied with measurements of the test mass position from these sensors and commands external micronewton thrusters to force the spacecraft to fly in formation with the test masses. Laser interferometry is used to measure the minute variations in the distance, or light travel time, between these purely free-falling TMs, caused by gravitational waves. We have constructed a new torsion pendulum facility with a force sensitivity in the range of pN/Hz1/2 around 1 mHz for testing new gravitational reference sensor technologies. This experimental facility consists of a vacuum enclosed torsion pendulum that suspends mock-ups of the LISA test masses, surrounded by their electrode housings. With the aid of this facility, we are (a) developing a novel test mass charge control scheme based on ultraviolet LEDs, (b) examining alternate test mass and electrode housing coatings, and (c) evaluating alternate operational modes of the LISA gravitational reference sensor. This presentation will describe this facility and the development status of these new technologies.

  17. Sub-Femto-g Free Fall for Space-Based Gravitational Wave Observatories: LISA Pathfinder Results.

    PubMed

    Armano, M; Audley, H; Auger, G; Baird, J T; Bassan, M; Binetruy, P; Born, M; Bortoluzzi, D; Brandt, N; Caleno, M; Carbone, L; Cavalleri, A; Cesarini, A; Ciani, G; Congedo, G; Cruise, A M; Danzmann, K; de Deus Silva, M; De Rosa, R; Diaz-Aguiló, M; Di Fiore, L; Diepholz, I; Dixon, G; Dolesi, R; Dunbar, N; Ferraioli, L; Ferroni, V; Fichter, W; Fitzsimons, E D; Flatscher, R; Freschi, M; García Marín, A F; García Marirrodriga, C; Gerndt, R; Gesa, L; Gibert, F; Giardini, D; Giusteri, R; Guzmán, F; Grado, A; Grimani, C; Grynagier, A; Grzymisch, J; Harrison, I; Heinzel, G; Hewitson, M; Hollington, D; Hoyland, D; Hueller, M; Inchauspé, H; Jennrich, O; Jetzer, P; Johann, U; Johlander, B; Karnesis, N; Kaune, B; Korsakova, N; Killow, C J; Lobo, J A; Lloro, I; Liu, L; López-Zaragoza, J P; Maarschalkerweerd, R; Mance, D; Martín, V; Martin-Polo, L; Martino, J; Martin-Porqueras, F; Madden, S; Mateos, I; McNamara, P W; Mendes, J; Mendes, L; Monsky, A; Nicolodi, D; Nofrarias, M; Paczkowski, S; Perreur-Lloyd, M; Petiteau, A; Pivato, P; Plagnol, E; Prat, P; Ragnit, U; Raïs, B; Ramos-Castro, J; Reiche, J; Robertson, D I; Rozemeijer, H; Rivas, F; Russano, G; Sanjuán, J; Sarra, P; Schleicher, A; Shaul, D; Slutsky, J; Sopuerta, C F; Stanga, R; Steier, F; Sumner, T; Texier, D; Thorpe, J I; Trenkel, C; Tröbs, M; Tu, H B; Vetrugno, D; Vitale, S; Wand, V; Wanner, G; Ward, H; Warren, C; Wass, P J; Wealthy, D; Weber, W J; Wissel, L; Wittchen, A; Zambotti, A; Zanoni, C; Ziegler, T; Zweifel, P

    2016-06-10

    We report the first results of the LISA Pathfinder in-flight experiment. The results demonstrate that two free-falling reference test masses, such as those needed for a space-based gravitational wave observatory like LISA, can be put in free fall with a relative acceleration noise with a square root of the power spectral density of 5.2±0.1  fm s^{-2}/sqrt[Hz], or (0.54±0.01)×10^{-15}  g/sqrt[Hz], with g the standard gravity, for frequencies between 0.7 and 20 mHz. This value is lower than the LISA Pathfinder requirement by more than a factor 5 and within a factor 1.25 of the requirement for the LISA mission, and is compatible with Brownian noise from viscous damping due to the residual gas surrounding the test masses. Above 60 mHz the acceleration noise is dominated by interferometer displacement readout noise at a level of (34.8±0.3)  fm/sqrt[Hz], about 2 orders of magnitude better than requirements. At f≤0.5  mHz we observe a low-frequency tail that stays below 12  fm s^{-2}/sqrt[Hz] down to 0.1 mHz. This performance would allow for a space-based gravitational wave observatory with a sensitivity close to what was originally foreseen for LISA.

  18. Proceedings of the International Miconia Conference

    USGS Publications Warehouse

    Loope, L.L.; Meyer, J.-Y.; Hardesty, B. D.; Smith, C.W.

    2015-01-01

    This proceedings is a compilation of 15 of the 27 papers and posters that were presented at the 2009 International Miconia Conference. The Conference was held in Keanae Hawaii May 4th to 7th 2009, hosted by the Maui Invasive Species Committee. *No official abstract was available for the proceedings...K. Keck

  19. International Summit on Integrated Environmental Modeling

    EPA Science Inventory

    This report describes the International Summit on Integrated Environmental Modeling (IEM), held in Washington, DC 7th-9th December 2010. The meeting brought together 57 scientists and managers from leading US and European government and non-governmental organizations, universitie...

  20. Abstracts of Plenary Lectures and Posters. International Symposium of the Structure and Function of Plant Lipids (7th) held in Davis, California on July 27-August 1, 1986,

    DTIC Science & Technology

    1986-08-01

    sis - of pigments and prenylquinones. 12 9 ARACHIDONIC AND EICOSAPENTAENOIC ACIDS, GLUCANS AND CALCIUM AS REGULATORS OF RESISTANCE TO A PLANT...components in the mycelium of the fungus.-A - Glucans from the fungus, though inactive as elicitors, enhance the activity of AA and EPA but they race...esterified AA are consistent with the free acid being the active agent. In the presence of appropriateA- glucans , elicitor activity of AA was detected at the

  1. Proceedings: The Annual Executive Seminar on International Security Affairs (7th). The Changing Scene Foreign Military Sales and Technology Transfer, Washington, DC, 16-17 March 1983.

    DTIC Science & Technology

    1983-03-17

    considerations refer to regions, types of * requirements, and national behavioral attitudes. The economic considerations are those relating to licensing and co...grading an M-48 is a heck of a lot cheaper than shipping in a brand new M-60, although there are arguments to be said on tb- score, as well. Certainly...friends in order to improve their ability to defend themselves and this is certainly evident in the increased value of commercial licenses . But on the

  2. Proceedings of the International Symposium on Methodologies for Intelligent Systems (Poster Session) (7th) held at Trondheim, Norway, on 15-18 June, 1993

    DTIC Science & Technology

    1993-06-18

    several classes the prototype occurrence is kept low. 5. EXPERIMENTAL RESULTS The Q*-algorithm will be used for experiments in inductive classification...Neural Network: Experiments in Learning to Play a Stochastic Game Neal M. Mazur ............. .......................... .. 55 Viewpoints and Selective...Acquisition by an Artificial Neural Network: Experiments in Learning to Play a Stochastic Game," Neal M. Mazur (Union College, USA) "Multivariate

  3. International Conference on MHD Electrical Power Generation, 7th, Massachusetts Institute of Technology, Cambridge, MA, June 16-20, 1980, Proceedings. Volumes 1, 2 & 3

    NASA Astrophysics Data System (ADS)

    Dawson, A. M.; Overlan, D.

    The first volume of this conference on magnetohydrodynamics (MHD) for electrical power generation covers: (1) MHD pilot plants; (2) MHD generator experiments and modeling; (3) the performance of various MHD generator types; (4) MHD channel design considerations; (5) MHD channel materials considerations; (6) MHD system components, heat recovery and emissions; and (7) MHD oxidizers and inverters. The second volume deals with (8) MHD system magnets and combustors; (9) MHD field, flow and chemical processes; (10) MHD fluid dynamics; (11) MHD electrical power plant design; (12) current transfer and diagnostics; and (13) MHD power plant systems considerations.

  4. 7TH International Workshop on Laser Physics (LPHYS󈨦) Berlin, Germany July 6-10, 1998 Program and Book of Abstracts: Volume 2.

    DTIC Science & Technology

    1998-07-01

    Phone: +1 401 863-1444, E-Mail: Theodore Morse@brown.edu ’Physical Sciences Inc., Andover, MA 01810. Abstract: A wavelength modulated Er3’ -Yb3’ doped...explants [Mester and Snow, 1990], Schwann cell proliferation [Van Breugel et al., 1991], astrocyte division [Yew et al., 1990], changes in striatal

  5. Proceedings of the International Cryocooler Conference (7th) Held in Santa Fe, New Mexico on 17-19 November 1992. Part 4

    DTIC Science & Technology

    1993-04-01

    contamination. 949 PL-CP--93-1001 High Pressure During the ABB program we Gas In have gone one step further. Capillay Channel I We’ve developed a capillary J...much help with solubility problemts. Therefore, a mixturc of nitrogenl, methane , ethane. and propane has been chosen for analysis as the operating...following steps. (I) The maximum solubility of methane in nitrogen (i.e. mol fraction ratio) is followed by a determination of the maximum solubility of

  6. International Symposium on Applications of Laser Techniques to Fluid Mechanics (7th) Held in Lisbon, Portugal on July 11-14, 1994. Volume 2

    DTIC Science & Technology

    1994-07-14

    than at fixed locations. clear, during the daylight. 10% of the solar radiation is For the Lagrangian investigation of the field, the adsorbed by the...significant displacement of heating of the earth surface due to the solar radiation. It the seeding particles between one image and the next. consists of a...hyperfine structure under M.L. Energia . Inc. and Schwartz Electro-Optics. Inc. components of the iodine molecule at 640 nm wavelength, Qi%,,mm... Vol

  7. Outcome of T4 (International Union Against Cancer Staging System, 7th edition) or Recurrent Nasal Cavity and Paranasal Sinus Carcinoma Treated With Proton Beam

    SciTech Connect

    Fukumitsu, Nobuyoshi; Okumura, Toshiyuki; Mizumoto, Masashi; Oshiro, Yoshiko; Hashimoto, Takayuki; Kanemoto, Ayae; Hashii, Haruko; Ohkawa, Ayako; Moritake, Takashi; Tsuboi, Koji; Tabuchi, Keiji; Wada, Tetsuro; Hara, Akira; Sakurai, Hideyuki

    2012-06-01

    Purpose: To investigate the clinical features, prognostic factors, and toxicity of treatment for unresectable carcinomas of the nasal cavity and paranasal sinus (NCPS) treated with proton beam therapy (PBT). Methods and Materials: Seventeen patients (13 men, 4 women) with unresectable carcinomas of the NCPS who underwent PBT at University of Tsukuba between 2001 and 2007 were analyzed. The patients' median age was 62 years (range, 30-83 years). The tumors were located in the nasal cavity in 3 patients, the frontal sinus in 1, the ethmoid sinus in 9, and the maxillary sinus in 4. The clinical stage was Stage IVA in 5 cases, IVB in 10, and recurrent in 2. The tumors were deemed unresectable for medical reasons in 16 patients and because of refusal at a previous hospital 4 months earlier in 1 patient. All the patients received PBT irradiation dose of 22-82.5 GyE and a total of 72.4-89.6 GyE over 30-64 fractions (median 78 GyE over 36 fractions) with X-ray, with attention not exceeding the delivery of 50 GyE to the optic chiasm and brainstem. Results: The overall survival rate was 47.1% at 2 years and 15.7% at 5 years, and the local control rate was 35.0% at 2 years and 17.5% at 5 years. Invasion of the frontal or sphenoid sinus was a prognostic factor for overall survival or local control. Late toxicity of more than Grade 3 was found in 2 patients (brain necrosis in 1 and ipsilateral blindness in 1); however, no mortal adverse effects were observed. Conclusion: Proton beam therapy enabled a reduced irradiation dose to the optic chiasm and brainstem, enabling the safe treatment of unresectable carcinomas in the NCPS. Superior or posterior extension of the tumor influenced patient outcome.

  8. Proceedings of the International Cryocooler Conference (7th) Held in Santa Fe, New Mexico on 17-19 November 1992. Part 2,

    DTIC Science & Technology

    1993-04-01

    presentations. The topics included Cryoccoler Testing and Modeling , Space and Long Life Applications, Stirling Cryocoolers , Pulse Tube Refrigerators, Novel...Equation (12), derived in the present study can also be used to develop a linear network model of Stirling 1" or pulse - tube cryocoolers by...Applications, Stirling Cryocoolers , Pulse Tube Refrigerators, Novel Concepts and Component Development, Low Temperature Regenerator Development, and J-T and

  9. Proceedings of the International Cryocooler Conference (7th) Held in Santa Fe, New Mexico on 17-19 November 1992, Part 1

    DTIC Science & Technology

    1993-04-01

    Cryocooler Testing and Modeling , Space and Long Life Applications, Stirling Cryocoolers , Pulse Tube Refrigerators, Novel Concepts and Component Development...included Cryocooler Testing and Modeling , Space and Long Life Applications, Stirling Cryocoolers , Pulse Tube Refrigerators, Novel Concepts and... METHOD TO ESTIMATE THE PULSE TUBE REFRIGERATOR PERFORMANCES ....M. Dav’d, J. Marechal, and Y. Simon ................................ 1078

  10. Proceedings of the International Workshop on Dynamics and Aeroelastic Modeling of Rotorcraft (7th) held in St. Louis, Missouri on 14-16 October, 1997

    DTIC Science & Technology

    1997-10-14

    Lett., 64(11):1196-1199,1990.- [4] E.R Hunt. Stabilizing high-period periodic orbits in a chaotic system: the diode resonator. Phys. Rev. Lett., 67...orthogonal to the ’ lTp , so that Wi M’lTp = 0 can be expressed in the following form: (E - wp2M) Wp = (’lT~EI + ifJ~Dll - cl>pApM) 1/Jp (11) here... Laser Doppler Velocimetry," Journal of the American Helicopter Society, Vol. 41, No.4, Oc- tober 1996, pp. 342-353. 42Coyne, A. J., Bhagwat, M. J

  11. 7TH International Workshop on Laser Physics (LPHYS󈨦) Berlin, Germany July 6-10, 1998 Program and Book of Abstracts: Volume 1.

    DTIC Science & Technology

    1998-07-01

    to a hydrodynamic expansion of the so-called " nanoplasma " into the vacuum. The relative weight of each of these two explosion mechanisms depends on... nanoplasma . In particular, we observe L-shell emission in the case of Krypton and Xenon clusters and K-shell emission for Argon. Our results concern the

  12. Numerical methods in laminar and turbulent flow; Proceedings of the 7th International Conference, Stanford Univ., CA, July 15-19, 1991. Vol. 7, pts. 1 & 2

    NASA Technical Reports Server (NTRS)

    Taylor, C. (Editor); Chin, J. H. (Editor); Homsy, G. M. (Editor)

    1991-01-01

    Consideration is given to the impulse response of a laminar boundary layer and receptivity; numerical transition to turbulence in plane Poiseuille flow; large eddy simulation of turbulent wake flow; a viscous model and loss calculation of a multisplitter cascade; vortex initiation during dynamic stall of an airfoil; a numerical analysis of isothermal flow in a combustion chamber; and compressible flow calculations with a two-equation turbulence model and unstructured grids. Attention is also given to a 2D calculation of a buoyant flow around a burning sphere, a fast multigrid method for 3D turbulent incompressible flows, a streaming flow induced by an oscillating cascade of circular cylinders, an algebraic multigrid scheme for solving the Navier-Stokes equations on unstructured meshes; and nonlinear coupled multigrid solutions to thermal problems employing different nodal grid arrangements and convective transport approximations.

  13. International Symposium on Applications of Laser Techniques to Fluid Mechanics (7th) Held in Lisbon, Portugal on July 11-14, 1994. Volume 1

    DTIC Science & Technology

    1994-07-14

    CHARACTERISTICS OF LOW MOLECULAR WEIGHT SHEAR-THINNING FLUIDS A. S. Pereira Departamento de Engenharia Quimica , Instituto Superior de Engenharia do Porto Rua...which, at ambient temperature, are 0.21 and 0.2 - 700 0.23 cm 2 /s, respectively. At 1000*C, they increase to 2.0 and 2.3 cm2 /s, which are many...1981)). The intermittency factor provides insight into the process of entrainment by indicating the location and extent to which ambient fluid

  14. Lecture Notes in Artificial Intelligence 689: Methodologies for Intelligent Systems: International Symposium, ISMIS 󈨡 (7th) Held at Trondheim (Norway) April 1993

    DTIC Science & Technology

    1993-06-18

    order to find the agent causing the pneumonia. This procedure or plan consists of the following actions: take an X-ray of the thorax, do an... agent causing pneumonia. Pneutmoniae are frequent illnnc~ses that need urgent treatmentl1lj. An early treat- nient means that tihe physician needs to...diagnose the agent that causes the infection by taking advantage of all the information he has about the patient, and before know- ing the results of

  15. Proceedings of the International Cryocooler Conference (7th) Held in Santa Fe, New Mexico on 17-19 November 1992. Part 3

    DTIC Science & Technology

    1993-04-01

    Exngneering Vol 36 * Purdue University, "TPRC Series - "weophysical Propertie - of Matter" edited by Touloukian and Ho, Plemzm. 777 PL-CP--93-1001...Measurements of these temr’n,’•tures along with the hydrogen pressu,6 changes have beer. .nalyzed to assess the rectloi, properties of the sorbent alloy ...consisting of GdNi 2 and an erbium alloy operating between 30-77K and 25-77K. The results show that the layered bed will have a 5.6% increase in

  16. International Symposium on Solute-Solute-Solvent Interactions (7th) Held at Reading, United Kingdom on 15-19 July 1985.

    DTIC Science & Technology

    2014-09-26

    TOMAT a and P . ZANO.ATCa aztitto di Chimca, Universita di Padova, Via Loredan 4, 35100, Padova, ITALY, Istituto di Chimica, Universita d Udine, Viale...9 (P) Rodehuser L. 2-13 (0) Toogood G.E. 2-23 (0) Roe-Yao Z. 5-3 (P) Tomat G. 3-9 (0) Rossky P.J. 2-Sess 2 Tripathi P.N. 4-15 (0) Ruangpornvisuti V.R

  17. Comparison of Values in 5th, 6th, 7th and 8th Grade Primary Education Music Class Students'? Workbooks According to Rokeach?s and Akbas's Value Classifications

    ERIC Educational Resources Information Center

    Çakirer, H. Serdar

    2014-01-01

    The aim of the present study is to compare the values in the songs of 5th, 6th, 7th and 8th grade primary education music classes students? workbooks according to the value categorizations proposed by Rockeach and Akbas and which values among the categories mentioned are taught to the students in the 5th, 6th, 7th and 8th grade primary education…

  18. Results from the LISA Commissioning Experiment on the decay of 24O* --> 22O + n

    NASA Astrophysics Data System (ADS)

    Rogers, Warren F.; MoNA Collaboration

    2014-09-01

    The Large multi-Institutional Scintillator Array (LISA) at NSCL, Michigan State University was constructed and tested by undergraduate students from several institutions in the MoNA (Modular Neutron Array) collaboration. LISA is used in conjunction with MoNA for detection of neutrons at large angles to the beam axis, corresponding to high energy decays from exotic nuclei at or beyond the neutron dripline. The LISA commissioning experiment was designed to measure and resolve neutron decays from the first two excited states (2+ and 1+) of 24O to the 23O ground state, using proton-knockout of 26F on a thin Be target. The trajectories of charged fragments at the site of the decay were identified using the Sweeper Magnet chamber detectors and inverse-tracking through the magnet. The two scintillator arrays measured the time of flight path of neutrons. Decay energies were determined using these decay kinematics and invariant mass spectroscopy. The two 24O states were previously observed, but with insufficient resolution to separate the two cleanly. This experiment provided sufficiently resolution to separate the two states cleanly. Results for the decay energies and comparison with Monte Carlo simulations will be presented. The Large multi-Institutional Scintillator Array (LISA) at NSCL, Michigan State University was constructed and tested by undergraduate students from several institutions in the MoNA (Modular Neutron Array) collaboration. LISA is used in conjunction with MoNA for detection of neutrons at large angles to the beam axis, corresponding to high energy decays from exotic nuclei at or beyond the neutron dripline. The LISA commissioning experiment was designed to measure and resolve neutron decays from the first two excited states (2+ and 1+) of 24O to the 23O ground state, using proton-knockout of 26F on a thin Be target. The trajectories of charged fragments at the site of the decay were identified using the Sweeper Magnet chamber detectors and inverse

  19. 78 FR 10172 - Lisa Anne Cornell and G. Ware Cornell, Jr. v. Princess Cruise Lines, Ltd. (Corp), Carnival PLC...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-13

    ... Lisa Anne Cornell and G. Ware Cornell, Jr. v. Princess Cruise Lines, Ltd. (Corp), Carnival PLC, and..., Jr., hereinafter ``Complainants,'' against Princess Cruise Lines, Ltd (Corp), Carnival plc, and Carnival Corporation hereinafter ``Respondents.'' Complainant alleges that: Respondent Princess...

  20. Precision Measurement of Complete Black Hole Binary Inspiral-Merger-Ringdown Signals with LISA

    NASA Technical Reports Server (NTRS)

    McWilliams, Sean T.

    2009-01-01

    Until recently, only the inspiral and ringdown phases of black hole binary (131-113) coalescences had been modeled. The merger signals, which were expected to be the most luminous portion of the total signal, were unavailable due to the technical difficulty of calculating the behavior of a BHB in this highly dynamical and non-linear regime. Advancements in the field of numerical relativity make it possible to include the merger segment of 131113 coalescence in the search for and characterization of gravitational wave signals. The implications for LISA include an increase in the event rate due to the increase in achievable signal-to-noise ratio, as well as potentially improved accuracy regarding the extraction of the source parameters. We investigate the degree to which mergers improve parameter estimation, by studying the impact of including mergers on achievable parameter accuracy over a significant range of masses and mass ratios for nonspinning systems, and its impact on LISA science.

  1. Possible Periodic Orbit Control Maneuvers for an eLISA Mission

    NASA Technical Reports Server (NTRS)

    Bender, Peter L.; Welter, Gary L.

    2012-01-01

    This paper investigates the possible application of periodic orbit control maneuvers for so-called evolved-LISA (eLISA) missions, i.e., missions for which the constellation arm lengths and mean distance from the Earth are substantially reduced. We find that for missions with arm lengths of 106 km and Earth-trailing distance ranging from approx. 12deg to 20deg over the science lifetime, the occasional use of the spacecraft micro-Newton thrusters for constellation configuration maintenance should be able to essentially eliminate constellation distortion caused by Earth-induced tidal forces at a cost to science time of only a few percent. With interior angle variation kept to approx. +/-0:1deg, the required changes in the angles between the laser beam pointing directions for the two arms from any spacecraft could be kept quite small. This would considerably simplify the apparatus necessary for changing the transmitted beam directions.

  2. Development of a Multi-axis Heterodyne Interferometry system for LISA

    NASA Astrophysics Data System (ADS)

    Fulda, Paul; Thorpe, James

    2017-01-01

    Precision laser interferometric readout of test mass position and angle is one of the key technologies enabling a space-based gravitational wave mission such as LISA. At Goddard Space Flight Center we are developing a test-bed to demonstrate a Multi-Axis Heterodyne Interferometry (MAHI) system capable of meeting the measurement, range of motion and noise requirements for the short-arm measurement (test-mass to spacecraft) of LISA. Crucially, this system will use an optical design, photoreceivers and phase measurement systems which are also suitable for the long-arm measurement (spacecraft to spacecraft), thus reducing mission complexity. We will report on the progress of the MAHI system development, including preliminary measurements from a table-top prototype MAHI system.

  3. LISA Pathfinder as a drag-free accelerometer powered thrust stand

    NASA Astrophysics Data System (ADS)

    Slutsky, Jacob; LISA Pathfinder Team

    2017-01-01

    The LISA Pathfinder (LPF) mission, launched to demonstrate technology for a future gravitational wave observatory in space, began in March 2016. ESA led, LPF is comprised of both European and NASA payloads, the LISA Technology Package (LTP) and Disturbance Reduction System (DRS), respectively. The LTP includes the two highest precision drag free accelerometers ever flown, as well as a high precision interferometer. DRS provides the Colloid Micro-Newton Thruster (CMNT) system, required to precisely maneuver the spacecraft. Additionally, DRS includes a complete Dynamic Control System (DCS) that maintains the drag free flight. While the LTP mission uses the residual of the differential acceleration between the accelerometers, each individual sensor provides an unparalleled measure of the full six-dimensional spacecraft motion. This talk will discuss the DRS experiments performed, and how this sensor data is analyzed to characterize the noise and performance of the CMNTs.

  4. Mona Lisa's smile: a hypothesis based on a new principle of art neuroscience.

    PubMed

    Chakravarty, Ambar

    2010-07-01

    The smile on Mona Lisa's face remains enigmatous and a topic of much discussion in art circle over the centuries. In this essay the author proposes a new principle of art neuroscience or the science of aesthetics namely 'dynamism' which artists often employ to impart an illusion of movement in their art works which are essentially static. This illusion is possibly generated through imaginative thinking which involves frontal cortical activation in the viewer's brain coupled with activation of the motion area (area V5/MT) of the viewer's visual cortex. It is suggested that this principle of dynamism is somewhat different from the previously described concept of kinetic art. The author hypothesizes that the great painter Leonardo da Vinci very intelligently painted the angles of the mouth of Mona Lisa's face to evoke this illusion of movement (smile) to increase the aesthetic value of this great work of art.

  5. Development of a US Laser System for the Gravitational Wave Mission LISA

    NASA Astrophysics Data System (ADS)

    Camp, Jordan; Numata, Kenji

    2016-07-01

    A highly stable and robust laser system is a key component of the space-based, Gravitational Wave mission LISA architecture. In this talk I will describe our plans to demonstrate a TRL 5 LISA laser system at Goddard Space Flight Center by 2017. The laser system includes a low-noise oscillator followed by a power amplifier. The oscillator is a low-mass, compact 10 mW External Cavity Laser, consisting of a semiconductor laser coupled to an optical cavity, built by the laser vendor Redfern Integrated Optics. The amplifier is a diode-pumped Yb fiber with 2.5 W output, built at Goddard. I will show noise and reliability data for the full laser system, and describe our plans to reach TRL 5 by 2017.

  6. Detection of Double White Dwarf Binaries with Gaia, LSST and eLISA

    NASA Astrophysics Data System (ADS)

    Korol, V.; Rossi, E. M.; Groot, P. J.

    2017-03-01

    According to simulations around 108 double degenerate white dwarf binaries are expected to be present in the Milky Way. Due to their intrinsic faintness, the detection of these systems is a challenge, and the total number of detected sources so far amounts only to a few tens. This will change in the next two decades with the advent of Gaia, the LSST and eLISA. We present an estimation of how many compact DWDs with orbital periods less than a few hours we will be able to detect 1) through electromagnetic radiation with Gaia and LSST and 2) through gravitational wave radiation with eLISA. We find that the sample of simultaneous electromagnetic and gravitational waves detections is expected to be substantial, and will provide us a powerful tool for probing the white dwarf astrophysics and the structure of the Milky Way, letting us into the era of multi-messenger astronomy for these sources.

  7. The new Digital Data Acquisition System for MoNA-LISA

    NASA Astrophysics Data System (ADS)

    Chrisman, Dayah; Deyoung, Paul; The MoNA Collaboration Collaboration

    2017-01-01

    The Modular Neutron Array (MoNA) and the Large multi-Institutional Scintillator Array (LISA) at the National Superconducting Cyclotron Laboratory (NSCL) are used to detect neutrons emitted during the decay of exotic nuclei near the neutron dripline. The arrays consist of 288 10cm x 10cm x 2m long plastic scintillation detectors coupled to photomultipliers at each end. The Time of Flight (TOF) of these neutrons determines the neutron energy, which is needed to find the decay energy of the exotic nuclei. A Digital Data Acquisition System (DDAS) based on the XIA PXI modules is being developed to read out and record the signals of the MoNA-LISA scintillation detectors. A 500 Mega Samples per Second (MSPS) PXI module was used to test the time and energy resolution as it compares to the existing analog DAQ setup. NSF PHY-1002511, DOE-NNSA DE-NA0000979.

  8. Thermo-elastic induced phase noise in the LISA Pathfinder spacecraft

    NASA Astrophysics Data System (ADS)

    Gibert, F.; Nofrarias, M.; Karnesis, N.; Gesa, L.; Martín, V.; Mateos, I.; Lobo, A.; Flatscher, R.; Gerardi, D.; Burkhardt, J.; Gerndt, R.; Robertson, D. I.; Ward, H.; McNamara, P. W.; Guzmán, F.; Hewitson, M.; Diepholz, I.; Reiche, J.; Heinzel, G.; Danzmann, K.

    2015-02-01

    During the on-station thermal test campaign of the LISA Pathfinder, the diagnostics subsystem was tested in nearly space conditions for the first time after integration in the satellite. The results showed the compliance of the temperature measurement system, obtaining temperature noise around {{10}-4} K H{{z}-1/2} in the frequency band 1-30 mHz. In addition, controlled injection of heat signals to the suspension struts anchoring the LISA Technology Package (LTP) core assembly to the satellite structure allowed us to experimentally estimate, for the first time, the phase noise contribution through thermo-elastic distortion of the LTP interferometer, the satellite's main instrument. Such contribution was found to be at {{10}-12} mH{{z}-1/2}, a factor of 30 below the measured noise at the lower end of the measurement bandwidth (1 mHz).

  9. Kolmogorov-Smirnov like test for time-frequency Fourier spectrogram analysis in LISA Pathfinder

    NASA Astrophysics Data System (ADS)

    Ferraioli, Luigi; Armano, Michele; Audley, Heather; Congedo, Giuseppe; Diepholz, Ingo; Gibert, Ferran; Hewitson, Martin; Hueller, Mauro; Karnesis, Nikolaos; Korsakova, Natalia; Nofrarias, Miquel; Plagnol, Eric; Vitale, Stefano

    2015-03-01

    A statistical procedure for the analysis of time-frequency noise maps is presented and applied to LISA Pathfinder mission synthetic data. The procedure is based on the Kolmogorov-Smirnov like test that is applied to the analysis of time-frequency noise maps produced with the spectrogram technique. The influence of the finite size windowing on the statistic of the test is calculated with a Monte Carlo simulation for 4 different windows type. Such calculation demonstrate that the test statistic is modified by the correlations introduced in the spectrum by the finite size of the window and by the correlations between different time bins originated by overlapping between windowed segments. The application of the test procedure to LISA Pathfinder data demonstrates the test capability of detecting non-stationary features in a noise time series that is simulating low frequency non-stationary noise in the system.

  10. Change of Cerebral Oxygenation during Surfactant Treatment in Preterm Infants: "LISA" versus "InSurE" Procedures.

    PubMed

    Bertini, Giovanna; Coviello, Caterina; Gozzini, Elena; Bianconi, Tommaso; Bresci, Cecilia; Leonardi, Valentina; Dani, Carlo

    2017-04-01

    Objectives The aim of the study was to compare the effects on cerebral oxygenation in preterm infants of two different procedures for surfactant administration: the LISA (low-invasive method of surfactant administration) and the InSurE (Intubation, SURfactant administration, Extubation). Study Design Twenty premature infants with respiratory distress syndrome were assigned to receive surfactant either by "LISA" (n = 10) or "InSurE" (n = 10) procedure. Patients were continuously studied by near-infrared spectroscopy (NIRS) for the measurement of cerebral regional oxygenation (rSO2C) and calculation of cerebral fractional oxygen extraction rate (cFTOE), and NIRS data were recorded 30 minutes before (T0) surfactant administration, during the procedure (Tproc), and 30 (T1), 60 (T2T2), and 120 minutes (T3) afterward. Cerebral blood flow velocity (CBFV) was studied in the anterior cerebral artery at T0, T1, and T3. Results SpO2 significantly decreased at Tproc in comparison with T0, T1, T2, and T3 and the decrease was higher in the LISA than in the InSurE group. rSO2C was lower at tproc and T3 in the LISA than in the InSurE group. cFTOE was higher at tproc, t2, and t3 in the LISA group than in the InSurE group. CBFV did not change during the study periods in both groups. Conclusions The LISA and InSurE procedures transiently decreased rSO2C in our population, and the decrease was higher in the LISA group. Consistently, there was a contemporary increase in cFTOE that was higher in the LISA than in the InSurE group, suggesting that it represents a compensatory mechanism.

  11. Effect of LISA Pathfinder spacecraft self-gravity on anomalous gravitational signals near the Sun-Earth saddle point predicted by quasilinear MOND

    NASA Astrophysics Data System (ADS)

    Trenkel, Christian; Wealthy, David

    2014-10-01

    The possibility of sending the LISA Pathfinder spacecraft through the Sun-Earth saddle point following its nominal mission around L1 has now been studied for a few years. The principal motivation for doing so is to search for anomalous gravity gradients predicted by several alternative theories of gravity. In turn, these have originally been motivated by the dark matter problem, and predict deviations from General Relativity in regions of low acceleration. All signal estimates to date have ignored the presence of the spacecraft mass distribution and its self-gravity, on the basis that the gravitational field due to Sun and Earth is larger than that due to the spacecraft itself, for any realistic saddle point fly-by distances. In this paper, we show that at least for one of the theoretical frameworks, Quasilinear MOdified Newtonian Dynamics (QMOND), the presence of the local mass distribution cannot be ignored. Using simplified representations of the spacecraft mass distribution, we demonstrate that internal self-gravity, in particular internal gravitational gradients, can enhance the QMOND signals by more than 3 orders of magnitude. These preliminary results indicate that the parameter space accessible to LISA Pathfinder may be significantly larger than previously thought. We find further that the details of the matter distribution as well as of the trajectory can affect the expected signal shape, due to the coupling between internal and external gravitational fields and field gradients. We hope that this work will motivate a more comprehensive investigation of the effect, not just in QMOND, but also in the context of other theoretical frameworks.

  12. Improving Bayesian analysis for LISA Pathfinder using an efficient Markov Chain Monte Carlo method

    NASA Astrophysics Data System (ADS)

    Ferraioli, Luigi; Porter, Edward K.; Armano, Michele; Audley, Heather; Congedo, Giuseppe; Diepholz, Ingo; Gibert, Ferran; Hewitson, Martin; Hueller, Mauro; Karnesis, Nikolaos; Korsakova, Natalia; Nofrarias, Miquel; Plagnol, Eric; Vitale, Stefano

    2014-02-01

    We present a parameter estimation procedure based on a Bayesian framework by applying a Markov Chain Monte Carlo algorithm to the calibration of the dynamical parameters of the LISA Pathfinder satellite. The method is based on the Metropolis-Hastings algorithm and a two-stage annealing treatment in order to ensure an effective exploration of the parameter space at the beginning of the chain. We compare two versions of the algorithm with an application to a LISA Pathfinder data analysis problem. The two algorithms share the same heating strategy but with one moving in coordinate directions using proposals from a multivariate Gaussian distribution, while the other uses the natural logarithm of some parameters and proposes jumps in the eigen-space of the Fisher Information matrix. The algorithm proposing jumps in the eigen-space of the Fisher Information matrix demonstrates a higher acceptance rate and a slightly better convergence towards the equilibrium parameter distributions in the application to LISA Pathfinder data. For this experiment, we return parameter values that are all within ˜1 σ of the injected values. When we analyse the accuracy of our parameter estimation in terms of the effect they have on the force-per-unit of mass noise, we find that the induced errors are three orders of magnitude less than the expected experimental uncertainty in the power spectral density.

  13. Metals in sediments and fish from Sea Lots and Point Lisas harbors, Trinidad and Tobago

    USGS Publications Warehouse

    Mohammed, Azad; May, Thomas; Echols, Kathy; Walther, Mike; Manoo, Anton; Maraj, Dexter; Agard, John; Orazio, Carl

    2012-01-01

    Concentrations of heavy metals were determined in nearshore marine sediments and fish tissue from Sea Lots area on the west coast, at Caroni Lagoon National Park, and in the Point Lisas harbor, Trinidad. The most dominant metals found in sediments were Al, Fe and Zn with mean concentrations highest at Sea Lots (Al-39420 μg/g; Fe-45640 μg/g; Zn-245 μg/g), when compared to sediments from Point Lisas (Al-11936 μg/g; Fe-30171 μg/g; Zn-69 μg/g) and Caroni (Al-0400 μg/g; Fe-19000 μg/g; Zn-32 μg/g), High concentration of Cu, Al, Fe and Zn were also detected in fish tissue from Point Lisas and Caroni. Metal concentrations in fish tissue showed significant correlation with sediment metals concentration, which suggests that tissue levels are influenced by sediment concentration. Of the metals, only Zn, Hg and Cu had a bioaccumulation factor (BAF) greater than one, which suggests a high bioaccumulation potential for these metals.

  14. Rapid, automated, parallel quantitative immunoassays using highly integrated microfluidics and AlphaLISA.

    PubMed

    Yu, Zeta Tak For; Guan, Huijiao; Cheung, Mei Ki; McHugh, Walker M; Cornell, Timothy T; Shanley, Thomas P; Kurabayashi, Katsuo; Fu, Jianping

    2015-06-15

    Immunoassays represent one of the most popular analytical methods for detection and quantification of biomolecules. However, conventional immunoassays such as ELISA and flow cytometry, even though providing high sensitivity and specificity and multiplexing capability, can be labor-intensive and prone to human error, making them unsuitable for standardized clinical diagnoses. Using a commercialized no-wash, homogeneous immunoassay technology ('AlphaLISA') in conjunction with integrated microfluidics, herein we developed a microfluidic immunoassay chip capable of rapid, automated, parallel immunoassays of microliter quantities of samples. Operation of the microfluidic immunoassay chip entailed rapid mixing and conjugation of AlphaLISA components with target analytes before quantitative imaging for analyte detections in up to eight samples simultaneously. Aspects such as fluid handling and operation, surface passivation, imaging uniformity, and detection sensitivity of the microfluidic immunoassay chip using AlphaLISA were investigated. The microfluidic immunoassay chip could detect one target analyte simultaneously for up to eight samples in 45 min with a limit of detection down to 10 pg mL(-1). The microfluidic immunoassay chip was further utilized for functional immunophenotyping to examine cytokine secretion from human immune cells stimulated ex vivo. Together, the microfluidic immunoassay chip provides a promising high-throughput, high-content platform for rapid, automated, parallel quantitative immunosensing applications.

  15. Metals in sediments and fish from Sea Lots and Point Lisas Harbors, Trinidad and Tobago

    USGS Publications Warehouse

    Mohammed, A.; May, T.; Echols, K.; Walther, M.; Manoo, A.; Maraj, D.; Agard, J.; Orazio, C.

    2012-01-01

    Concentrations of heavy metals were determined in nearshore marine sediments and fish tissue from Sea Lots area on the west coast, at Caroni Lagoon National Park, and in the Point Lisas harbor, Trinidad. The most dominant metals found in sediments were Al, Fe and Zn with mean concentrations highest at Sea Lots (Al-39420 ??g/g; Fe-45640 ??g/g; Zn-245 ??g/g), when compared to sediments from Point Lisas (Al-11936 ??g/g; Fe-30171 ??g/g; Zn-69 ??g/g) and Caroni (Al-0400 ??g/g; Fe-19000 ??g/g; Zn-32 ??g/g), High concentration of Cu, Al, Fe and Zn were also detected in fish tissue from Point Lisas and Caroni. Metal concentrations in fish tissue showed significant correlation with sediment metals concentration, which suggests that tissue levels are influenced by sediment concentration. Of the metals, only Zn, Hg and Cu had a bioaccumulation factor (BAF) greater than one, which suggests a high bioaccumulation potential for these metals. ?? 2011 Elsevier Ltd.

  16. Calibrating spectral estimation for the LISA Technology Package with multichannel synthetic noise generation

    NASA Astrophysics Data System (ADS)

    Ferraioli, Luigi; Hueller, Mauro; Vitale, Stefano; Heinzel, Gerhard; Hewitson, Martin; Monsky, Anneke; Nofrarias, Miquel

    2010-08-01

    The scientific objectives of the LISA Technology Package experiment on board of the LISA Pathfinder mission demand accurate calibration and validation of the data analysis tools in advance of the mission launch. The level of confidence required in the mission outcomes can be reached only by intensively testing the tools on synthetically generated data. A flexible procedure allowing the generation of a cross-correlated stationary noise time series was set up. A multichannel time series with the desired cross-correlation behavior can be generated once a model for a multichannel cross-spectral matrix is provided. The core of the procedure comprises a noise coloring, multichannel filter designed via a frequency-by-frequency eigendecomposition of the model cross-spectral matrix and a subsequent fit in the Z domain. The common problem of initial transients in a filtered time series is solved with a proper initialization of the filter recursion equations. The noise generator performance was tested in a two-dimensional case study of the closed-loop LISA Technology Package dynamics along the two principal degrees of freedom.

  17. Metals in sediments and fish from Sea Lots and Point Lisas harbors, Trinidad and Tobago

    USGS Publications Warehouse

    Mohammed, Azad; May, Thomas; Echols, Kathy; Walther, Mike; Manoo, Anton; Maraj, Dexter; Agard, John; Orazio, Carl

    2012-01-01

    Concentrations of heavy metals were determined in nearshore marine sediments and fish tissue from Sea Lots area on the west coast, at Caroni Lagoon National Park, and in the Point Lisas harbor, Trinidad. The most dominant metals found in sediments were Al, Fe and Zn with mean concentrations highest at Sea Lots (Al-39420 μg/g; Fe-45640 μg/g; Zn-245 μg/g), when compared to sediments from Point Lisas (Al-11936 μg/g; Fe-30171 μg/g; Zn-69 μg/g) and Caroni (Al-0400 μg/g; Fe-19000 μg/g; Zn-32 μg/g), High concentration of Cu, Al, Fe and Zn were also detected in fish tissue from Point Lisas and Caroni. Metal concentrations in fish tissue showed significant correlation with sediment metals concentration, which suggests that tissue levels are influenced by sediment concentration. Of the metals, only Zn, Hg and Cu had a bioaccumulation factor (BAF) greater than one, which suggests a high bioaccumulation potential for these metals.

  18. Premerger localization of gravitational-wave standard sirens with LISA: Harmonic mode decomposition

    NASA Astrophysics Data System (ADS)

    Kocsis, Bence; Haiman, Zoltán; Menou, Kristen; Frei, Zsolt

    2007-07-01

    The continuous improvement in localization errors (sky position and distance) in real time as LISA observes the gradual inspiral of a supermassive black hole binary can be of great help in identifying any prompt electromagnetic counterpart associated with the merger. We develop a new method, based on a Fourier decomposition of the time-dependent, LISA-modulated gravitational-wave signal, to study this intricate problem. The method is faster than standard Monte Carlo simulations by orders of magnitude. By surveying the parameter space of potential LISA sources, we find that counterparts to supermassive black hole binary mergers with total mass M˜105 107M⊙ and redshifts z≲3 can be localized to within the field of view of astronomical instruments (˜deg2) typically hours to weeks prior to coalescence. This will allow a triggered search for variable electromagnetic counterparts as the merger proceeds, as well as monitoring of the most energetic coalescence phase. A rich set of astrophysical and cosmological applications would emerge from the identification of electromagnetic counterparts to these gravitational-wave standard sirens.

  19. Efficiently Simulating the Evolution of Massive Black Holes, and Implications for NANOGrav and LISA

    NASA Astrophysics Data System (ADS)

    McWilliams, Sean

    2017-01-01

    The coalescence of massive black-hole binaries is the principle target source for existing pulsar timing arrays (PTAs) like NANOGrav, and future spaced-based observatories like LISA. For the very massive sources that occur in the PTA band, the massive elliptical host galaxies are thought to evolve primarily through mergers, whereas at the lower masses that will be observed by LISA, other factors such as star formation and accretion must be accounted for. We discuss a novel approach to simulate this evolution that avoids expensive numerical simulations by calibrating to galaxy observations, but which ensures a self-consistent merger model by requiring that the sum of all effects on galaxy and black hole growth actually yield the galaxy evolution that we observe. By optimizing this new approach, we are able to simulate many realizations of the Universe, including a variety of evolutionary scenarios, and what impact they have on the signal observable by PTAs. We will also discuss the extension of this approach to predicting LISA event rates, and the challenges that must be overcome if we are to reliably simulate this lower mass population.

  20. Low-Frequency Gravitational-Wave Science with eLISA/ NGO

    NASA Technical Reports Server (NTRS)

    Amaro-Seoane, Pau; Aoudia, Sofiane; Babak, Stanislav; Binetruy, Pierre; Berti, Emanuele; Bohe, Alejandro; Caprini, Chiara; Colpi, Monica; Cornish, Neil J.; Danzmann, Karsten; Dufaux, Jean-Francois; Gair, Jonathan; Jennrich, Oliver; Jetzer, Philippe; Klein, Antoine; Lang, Ryan N.; Lobo, Alberto; Littenberg, Tyson; McWilliams, Sean T.; Nelemans, Gijs; Petiteau, Antoine; Porter, Edward K.; Schutz, Bernard F.; Stebbins, Robin; Vallisneri, Michele

    2011-01-01

    We review the expected science performance of the New Gravitational-Wave Observatory (NGO, a.k.a. eLISA), a mission under study by the European Space Agency for launch in the early 2020s. eLISA will survey the low-frequency gravitational-wave sky (from 0.1 mHz to 1 Hz), detecting and characterizing a broad variety of systems and events throughout the Universe, including the coalescences of massive black holes brought together by galaxy mergers; the inspirals of stellar-mass black holes and compact stars into central galactic black holes; several millions of ultracompact binaries, both detached and mass transferring, in the Galaxy; and possibly unforeseen sources such as the relic gravitational-wave radiation from the early Universe. eLISA's high signal-to-noise measurements will provide new insight into the structure and history of the Universe, and they will test general relativity in its strong-field dynamical regime.

  1. Topics in gravitation - numerical simulations of event horizons and parameter estimation for LISA

    NASA Astrophysics Data System (ADS)

    Cohen, Michael Isaac

    2011-08-01

    In Part I, we consider numerical simulations of event horizons. Event horizons are the defining physical features of black hole spacetimes, and are of considerable interest in studying black hole dynamics. Here, we reconsider three techniques to find event horizons in numerical spacetimes, and find that straightforward integration of geodesics backward in time is most robust. We apply this method to various systems, from a highly spinning Kerr hole through to an asymmetric binary black hole inspiral. We find that the exponential rate at which outgoing null geodesics diverge from the event horizon of a Kerr black hole is the surface gravity of the hole. In head-on mergers we are able to track quasi-normal ringing of the merged black hole through seven oscillations, covering a dynamic range of about 10^5. In the head-on "kick" merger, we find that computing the Landau-Lifshitz velocity of the event horizon is very useful for an improved understanding of the kick behaviour. Finally, in the inspiral simulations, we find that the topological structure of the black holes does not produce an intermediate toroidal phase, though the structure is consistent with a potential re-slicing of the spacetime in order to introduce such a phase. We further discuss the topological structure of non-axisymmetric collisions. In Part II, we consider parameter estimation of cosmic string burst gravitational waves in Mock LISA data. A network of observable, macroscopic cosmic (super-)strings may well have formed in the early Universe. If so, the cusps that generically develop on cosmic-string loops emit bursts of gravitational radiation that could be detectable by gravitational-wave interferometers, such as the ground-based LIGO/Virgo detectors and the planned, space-based LISA detector. We develop two versions of a LISA-oriented string-burst search pipeline within the context of the Mock LISA Data Challenges, which rely on the publicly available MultiNest and PyMC software packages

  2. Hybrid local FEM/global LISA modeling of guided wave propagation and interaction with damage in composite structures

    NASA Astrophysics Data System (ADS)

    Shen, Yanfeng; Cesnik, Carlos E. S.

    2015-03-01

    This paper presents a hybrid modeling technique for the efficient simulation of guided wave propagation and interaction with damage in composite structures. This hybrid approach uses a local finite element model (FEM) to compute the excitability of guided waves generated by piezoelectric transducers, while the global domain wave propagation, wave-damage interaction, and boundary reflections are modeled with the local interaction simulation approach (LISA). A small-size multi-physics FEM with non-reflective boundaries (NRB) was built to obtain the excitability information of guided waves generated by the transmitter. Frequency-domain harmonic analysis was carried out to obtain the solution for all the frequencies of interest. Fourier and inverse Fourier transform and frequency domain convolution techniques are used to obtain the time domain 3-D displacement field underneath the transmitter under an arbitrary excitation. This 3-D displacement field is then fed into the highly efficient time domain LISA simulation module to compute guided wave propagation, interaction with damage, and reflections at structural boundaries. The damping effect of composite materials was considered in the modified LISA formulation. The grids for complex structures were generated using commercial FEM preprocessors and converted to LISA connectivity format. Parallelization of the global LISA solution was achieved through Compute Unified Design Architecture (CUDA) running on Graphical Processing Unit (GPU). The multi-physics local FEM can reliably capture the detailed dimensions and local dynamics of the piezoelectric transducers. The global domain LISA can accurately solve the 3-D elastodynamic wave equations in a highly efficient manner. By combining the local FEM with global LISA, the efficient and accurate simulation of guided wave structural health monitoring procedure is achieved. Two numerical case studies are presented: (1) wave propagation in a unidirectional CFRP composite plate

  3. LISA: a web-based decision-support system for trial management of childhood acute lymphoblastic leukaemia.

    PubMed

    Bury, Jonathan; Hurt, Chris; Roy, Anindita; Cheesman, Louise; Bradburn, Mike; Cross, Simon; Fox, John; Saha, Vaskar

    2005-06-01

    Continuation chemotherapy is a key component of the treatment of childhood acute lymphoblastic leukaemia. During this treatment phase, weekly dose adjustments are carried out based on current and historical full blood counts (FBCs). The dose decision pathway is complex and suboptimal therapy may result if information on FBC results is not readily available and/or the prescriber is inexperienced. A web-based decision-support system (Leukaemia Intervention Scheduling and Advice, 'LISA') was designed to facilitate access to FBC information across geographical locations and to assist with dosage adjustments. A balanced-block crossover analysis was performed to evaluate the system. Thirty-six clinicians with varying degrees of experience were each asked to decide on appropriate oral chemotherapy dosages for eight simulated cases: four using LISA and four without. LISA significantly reduced the number of erroneous prescriptions (zero of 144 with LISA vs. 54 of 144 without; P < 0.0001) without affecting the number of times subjects deliberately overrode the protocol (seven of 144 times using LISA and six of 144 without). Using LISA reduced the time taken by novices to reach a decision for each case but increased the time taken by experts. Thirty-five of 36 subjects said they would be likely to use the system if it were available. A system like LISA is likely to be acceptable to clinicians, and has the potential to increase protocol compliance and decrease prescribing errors while allowing clinicians to override the protocol in specific cases where sound reasons exist for doing so.

  4. PREFACE: IARD 2010: The 7th Biennial Conference on Classical and Quantum Relativistic Dynamics of Particles and Fields

    NASA Astrophysics Data System (ADS)

    Horwitz, Lawrence; Hu, Bei-Lok; Lee, Da-Shin; Gill, Tepper; Land, Martin

    2011-12-01

    properties of spacetime structure. The scope of this series of conferences is, however, much wider. There have been recent develpments in the understanding of the quantum properties of spacetime, the application of quantum field theory and statistical quantum field theory to problems in relativistic dynamics, as well as new techniques in general relativity; some of these topics have been discussed in the IARD 2010 conference, and which will be reported in these Proceedings. It was for this purpose, to bring together researchers from a wide variety of fields, such as particle physics, astrophysics, cosmology, heavy ion collisions, plasma research, and mathematical physics, with a common interest in relativistic dynamics, that this Association was founded. The International Association for Relativistic Dynamics was organized at its first meeting as an informal session of seminars among researchers with common interest in February 1998 in Houston, Texas, with John R Fanchi as president. The second meeting took place, in 2000, at Bar Ilan University in Ramat Gan, Israel, the third, in 2002, at Howard University in Washington, DC, and the fourth, on 12-19 June 2004, in Saas Fee, Switzerland. In 2006, the meeting took place at the University of Connecticut campus in Storrs, Connecticut, and the sixth meeting, in Thessaloniki, Greece. The seventh meeting, took place at the National Dong Hwa University in Hulien, Taiwan from 30 May to 1 June 2010. This meeting forms the basis for the Proceedings that are recorded in this volume of Journal of Physics: Conference Series. Along with the work of some of the founding members of the Association, we were fortunate to have lecturers from application areas that provided strong challenges for further developments in quantum field theory, statistical quantum field theory and its potential applications to relativistic quantum information theory, cosmological problems, and in the dynamics of systems described in the framework of general

  5. Premerger Localization of Gravitational Wave Standard Sirens with LISA: Triggered Search for an Electromagnetic Counterpart

    NASA Astrophysics Data System (ADS)

    Kocsis, Bence; Haiman, Zoltán; Menou, Kristen

    2008-09-01

    Electromagnetic (EM) counterparts to SMBH binary mergers observed by LISA can be localized to within the field of view of astronomical instruments (~10 deg2) hours to weeks prior to coalescence. The temporal coincidence of any prompt EM counterpart with a gravitationally timed merger may offer the best chance of identifying a unique host galaxy. We discuss the challenges posed by searches for such prompt EM counterparts and propose novel observational strategies to address them. In particular, we discuss the size and shape evolution of the LISA localization error ellipses on the sky and quantify the corresponding requirements for dedicated EM surveys of the area prior to coalescence. A triggered EM counterpart search campaign will require monitoring a several square degree area. It could aim for variability at the 24-27 mag level in optical bands, for example, which corresponds to 1%-10% of the Eddington luminosity of the prime LISA sources of ~106-107 M⊙ BHs at z = 1-2, on timescales of minutes to hours, the orbital timescale of the binary in the last 2-4 weeks of coalescence. A cross-correlation of the period of any variable EM signal with the quasi-periodic gravitational waveform over 10-1000 cycles may aid the detection. Alternatively, EM searches can detect a transient signal accompanying the coalescence. The triggered searches will be ambitious, but if they successfully identify a unique prompt EM counterpart, they will enable new fundamental tests of gravitational physics. We highlight the measurement of differences in the arrival times of photons and gravitons from the same cosmological source as a valuable independent test of the massive character of gravity and of possible violations of Lorentz invariance in the gravity sector.

  6. Frequency-Tuneable Pre-Stabilized Lasers for LISA via Sideband Locking

    NASA Technical Reports Server (NTRS)

    Thorpe, James Ira; Numata, Kenji; Livas, jeffery

    2008-01-01

    Laser frequency noise mitigation is one of the most challenging aspects of the LISA interferometric measurement system. The unstabilized frequency fluctuations must be suppressed by roughly twelve orders of magnitude in order to achieve a stability sufficient for gravitational wave detection. This enormous suppression will be achieved through a combination of stabilization and common-mode rejection. The stabilization component will itself be achieved in two stages: pre-stabilization to a local optical cavity followed by arm-locking to some combination of the inter-spacecraft distances. In order for these two stabilization stages to work simultaneously, the lock-point of the pre-stabilization loop must be frequency tunable. The current baseline stabilization technique, locking to an optical cavity, does not provide tunability between cavity resonance, which are typically spaced by 100s of MHz. Here we present a modification to the traditional Pound-Drever-Hall cavity locking technique that allows the laser to be locked to a cavity resonance with an adjustable frequency offset. This technique requires no modifications to the optical cavity itself, thus preserving the stability of the frequency reference. We present measurements of the system stability, demonstrating that the pre-stabilization level satisfies LISA requirements. We also present a demonstration of a phase-lock loop which utilizes the tunable sideband locking technique as a pre-stabilizations tage. The performance of the pre-stabilized phase-lock-loop indicates that the tunable sideband technique will meet the requirements as an actuator for arm-locking in LISA.

  7. Constraining early and interacting dark energy with gravitational wave standard sirens: the potential of the eLISA mission

    NASA Astrophysics Data System (ADS)

    Caprini, Chiara; Tamanini, Nicola

    2016-10-01

    We perform a forecast analysis of the capability of the eLISA space-based interferometer to constrain models of early and interacting dark energy using gravitational wave standard sirens. We employ simulated catalogues of standard sirens given by merging massive black hole binaries visible by eLISA, with an electromagnetic counterpart detectable by future telescopes. We consider three-arms mission designs with arm length of 1, 2 and 5 million km, 5 years of mission duration and the best-level low frequency noise as recently tested by the LISA Pathfinder. Standard sirens with eLISA give access to an intermediate range of redshift 1 lesssim z lesssim 8, and can therefore provide competitive constraints on models where the onset of the deviation from ΛCDM (i.e. the epoch when early dark energy starts to be non-negligible, or when the interaction with dark matter begins) occurs relatively late, at z lesssim 6. If instead early or interacting dark energy is relevant already in the pre-recombination era, current cosmological probes (especially the cosmic microwave background) are more efficient than eLISA in constraining these models, except possibly in the interacting dark energy model if the energy exchange is proportional to the energy density of dark energy.

  8. Evaluating Earth and Space Sciences STEM Research Communication in 7th-12th Grade Rural Mississippi Classrooms and Resulting Student Attitudinal Impacts

    NASA Astrophysics Data System (ADS)

    Radencic, S.; McNeal, K. S.

    2013-05-01

    Observation and evaluation of STEM graduate students from Mississippi State University communicating their research of the Earth and Space Sciences in rural 7th-12th grade classrooms participating in the Initiating New Science Partnerships in Rural Education (INSPIRE) NSF GK-12 project. The methods they utilize to communicate their STEM research includes introducing new technologies and inquiry based learning experiences. These communication experiences have been observed and evaluated using two observational systems, the Mathematics Science Classroom Observational Profile System (M-SCOPS) and the Presentation Skills Protocol (PSP). M-SCOPS has been used over the first three years of the project to evaluate what Earth and Space research the STEM graduate students communicate in classroom activities along with how they are introducing STEM research through a variety of communication methods and levels of understanding. PSP, which INSPIRE began using this year, evaluates and provides feedback to the STEM graduate students on their communication during these classroom experiences using a rubric covering a range of skills for successful communication. PSP also allows the participating INSPIRE teacher partners to provide feedback to the STEM graduate students about development of their communication skills over the course of the year. In addition to feedback from the INSPIRE project and participating teachers, the STEM graduate students have the opportunity to evaluate their personal communication skills through video documentation to determine specific skills they would like to improve. Another area of research to be discussed is how the STEM graduate students communicating Earth and Space sciences research in the participating classrooms is impacting student attitudes about science and mathematics over the last three years. Student Attitudinal Surveys (SAS) are administered as a pre-evaluation tool in the fall when the STEM graduate students first enter into their

  9. Massive Black Hole Mergers: Can We "See" what LISA will "Hear"?

    NASA Technical Reports Server (NTRS)

    Centrella, Joan

    2010-01-01

    The final merger of massive black holes produces strong gravitational radiation that can be detected by the space-borne LISA. If the black hole merger takes place in the presence of gas and magnetic fields, various types of electromagnetic signals may also be produced. Modeling such electromagnetic counterparts of the final merger requires evolving the behavior of both gas and fields in the strong-field regions around the black holes. We will review current efforts to simulate these systems, and discuss possibilities for observing the electromagnetic signals they produce.

  10. LISA, the next generation: from a web-based application to a fat client.

    PubMed

    Pierlet, Noëlla; Aerts, Werner; Vanautgaerden, Mark; Van den Bosch, Bart; De Deurwaerder, André; Schils, Erik; Noppe, Thomas

    2008-01-01

    The LISA application, developed by the University Hospitals Leuven, permits referring physicians to consult the electronic medical records of their patients over the internet in a highly secure way. We decided to completely change the way we secured the application, discard the existing web application and build a completely new application, based on the in-house developed hospital information system, used in the University Hospitals Leuven. The result is a fat Java client, running on a Windows Terminal Server, secured by a commercial SSL-VPN solution.

  11. Interferometric characterization and modeling of pathlength errors resulting from beamwalk across mirror surfaces in LISA.

    PubMed

    Kögel, Harald; Gerardi, Domenico; Pijnenburg, Joep; Gohlke, Martin; Schuldt, Thilo; Johann, Ulrich; Braxmaier, Claus; Weise, Dennis

    2013-05-20

    An alternative payload concept with in-field pointing for the laser interferometer space antenna utilizes an actuated mirror in the telescope for beam tracking to the distant satellite. This actuation generates optical pathlength variations due to the resulting beamwalk over the surface of subsequent optical components, which could possibly have a detrimental influence on the accuracy of the measurement instrument. We have experimentally characterized such pathlength errors caused by a λ/10 mirror surface and used the results to validate a theoretical model. This model is then applied to predict the impact of this effect for the current optical design of the LISA off-axis wide-field telescope.

  12. Orbit Design and Optimization for the Gravitational Wave Detection of LISA

    NASA Astrophysics Data System (ADS)

    Xia, Y.; Li, G.; Luo, Y.; Yi, Z.; Heinzel, G.; Rüdiger, A.

    2010-04-01

    The Laser Interferometer Space Antenna (LISA) is a joint ESA-NASA mission for detecting low-frequency gravitational waves, by using accurate distance measurements with laser interferometry between three spacecrafts, which will be launched around 2018 and one year later reach their operational orbits around the Sun. In order to operate successfully, it is crucial for the constellation of the three spacecrafts to have extremely high stability. Based on the study of operational orbits for a 2015 launch, we designed the operational orbits of beginning epoch on 2019-03-01, analyzed the acceptable error range of the injection, and introduced the method of orbit design and optimization.

  13. Qualifciation test series of the indium needle FEEP micro-propulsion system for LISA Pathfinder

    NASA Astrophysics Data System (ADS)

    Scharlemann, C.; Buldrini, N.; Killinger, R.; Jentsch, M.; Polli, A.; Ceruti, L.; Serafini, L.; DiCara, D.; Nicolini, D.

    2011-11-01

    The Laser Interferometer Space Antenna project (LISA) is a co-operative program between ESA and NASA to detect gravitational waves by measuring distortions in the space-time fabric. LISA Pathfinder is the precursor mission to LISA designed to validate the core technologies intended for LISA. One of the enabling technologies is the micro-propulsion system based on field emission thrusters necessary to achieve the uniquely stringent propulsion requirements. A consortium consisting of Astrium GmbH and the University of Applied Sciences Wiener Neustadt (formerly AIT) was commissioned by ESA to develop and qualify the micro-propulsion system based on the Indium Needle FEEP technology. Several successful tests have verified the proper Needle Field Emission Electric Propulsion (FEEP) operation and the thermal and mechanical design of subcomponents of the developed system. For all functional tests, the flight representative Power Control Unit developed by SELEX Galileo S.p.A (also responsible for the Micro-Propulsion Subsystem (MPS) development) was used. Measurements have shown the exceptional stability of the thruster. An acceptance test of one Thruster Cluster Assembly (TCA) over 3600 h has shown the stable long term operation of the developed system. During the acceptance test compliance to all the applicable requirements have been shown such as a thrust resolution of 0.1 μN, thrust range capability between 0 and 100 μN, thrust overshoot much lower than the required 0.3 μN+3% and many others. In particular important is the voltage stability of the thruster (±1% over the duration of the testing) and the confirmation of the very low thrust noise. Based on the acceptance test the lifetime of the thruster is expected to exceed 39,000 h generating a total impulse bit of 6300 Ns at an average thrust level of 50 μN. A flight representative qualification model of the Needle FEEP Cluster Assembly (DM1) equipped with one active TCA has performed a qualification program

  14. Impact of Merger/Ringdown on SMBHB Parameter Estimation with LISA

    NASA Technical Reports Server (NTRS)

    Thorpe, James I.

    2010-01-01

    The Laser Interferometer Space Antenna (LISA) will measure gravitational waves from the inspiral and merger of supermassive black hole bina ries (SMBHBs) at high redshift with large signal to noise. These meas urements will allow extraction of the SMBHB parameters (component mas ses, spins, binary orbital parameters, sky location, and distance) wi th exquisite accuracy. Here we present a study of the impact on measu red parameter precision from the inclusion of accurate waveforms for the merger/ringdown portion of the signal. we focus specifically on s ky-position and luminosity distance, the most important parameters fo r constraining searches for potential electromagnetic counterparts to SMBHB merger events.

  15. Magnetic resonance imaging of the internal auditory canal

    SciTech Connect

    Daniels, D.L.; Herfkins, R.; Koehler, P.R.; Millen, S.J.; Shaffer, K.A.; Williams, A.L.; Haughton, V.M.

    1984-04-01

    Three patients with exclusively or predominantly intracanalicular neuromas and 5 with presumably normal internal auditory canals were examined with prototype 1.4- or 1.5-tesla magnetic resonance (MR) scanners. MR images showed the 7th and 8th cranial nerves in the internal auditory canal. The intracanalicular neuromas had larger diameter and slightly greater signal strength than the nerves. Early results suggest that minimal enlargement of the nerves can be detected even in the internal auditory canal.

  16. One-year oral toxicity study on a genetically modified maize MON810 variety in Wistar Han RCC rats (EU 7th Framework Programme project GRACE).

    PubMed

    Zeljenková, Dagmar; Aláčová, Radka; Ondrejková, Júlia; Ambrušová, Katarína; Bartušová, Mária; Kebis, Anton; Kovrižnych, Jevgenij; Rollerová, Eva; Szabová, Elena; Wimmerová, Soňa; Černák, Martin; Krivošíková, Zora; Kuricová, Miroslava; Líšková, Aurélia; Spustová, Viera; Tulinská, Jana; Levkut, Mikuláš; Révajová, Viera; Ševčíková, Zuzana; Schmidt, Kerstin; Schmidtke, Jörg; Schmidt, Paul; La Paz, Jose Luis; Corujo, Maria; Pla, Maria; Kleter, Gijs A; Kok, Esther J; Sharbati, Jutta; Bohmer, Marc; Bohmer, Nils; Einspanier, Ralf; Adel-Patient, Karine; Spök, Armin; Pöting, Annette; Kohl, Christian; Wilhelm, Ralf; Schiemann, Joachim; Steinberg, Pablo

    2016-10-01

    The GRACE (GMO Risk Assessment and Communication of Evidence; www.grace-fp7.eu ) project was funded by the European Commission within the 7th Framework Programme. A key objective of GRACE was to conduct 90-day animal feeding trials, animal studies with an extended time frame as well as analytical, in vitro and in silico studies on genetically modified (GM) maize in order to comparatively evaluate their use in GM plant risk assessment. In the present study, the results of a 1-year feeding trial with a GM maize MON810 variety, its near-isogenic non-GM comparator and an additional conventional maize variety are presented. The feeding trials were performed by taking into account the guidance for such studies published by the EFSA Scientific Committee in 2011 and the OECD Test Guideline 452. The results obtained show that the MON810 maize at a level of up to 33 % in the diet did not induce adverse effects in male and female Wistar Han RCC rats after a chronic exposure.

  17. Ninety-day oral toxicity studies on two genetically modified maize MON810 varieties in Wistar Han RCC rats (EU 7th Framework Programme project GRACE).

    PubMed

    Zeljenková, Dagmar; Ambrušová, Katarína; Bartušová, Mária; Kebis, Anton; Kovrižnych, Jevgenij; Krivošíková, Zora; Kuricová, Miroslava; Líšková, Aurélia; Rollerová, Eva; Spustová, Viera; Szabová, Elena; Tulinská, Jana; Wimmerová, Soňa; Levkut, Mikuláš; Révajová, Viera; Ševčíková, Zuzana; Schmidt, Kerstin; Schmidtke, Jörg; La Paz, Jose Luis; Corujo, Maria; Pla, Maria; Kleter, Gijs A; Kok, Esther J; Sharbati, Jutta; Hanisch, Carlos; Einspanier, Ralf; Adel-Patient, Karine; Wal, Jean-Michel; Spök, Armin; Pöting, Annette; Kohl, Christian; Wilhelm, Ralf; Schiemann, Joachim; Steinberg, Pablo

    2014-12-01

    The GMO Risk Assessment and Communication of Evidence (GRACE; www.grace-fp7.eu ) project is funded by the European Commission within the 7th Framework Programme. A key objective of GRACE is to conduct 90-day animal feeding trials, animal studies with an extended time frame as well as analytical, in vitro and in silico studies on genetically modified (GM) maize in order to comparatively evaluate their use in GM plant risk assessment. In the present study, the results of two 90-day feeding trials with two different GM maize MON810 varieties, their near-isogenic non-GM varieties and four additional conventional maize varieties are presented. The feeding trials were performed by taking into account the guidance for such studies published by the EFSA Scientific Committee in 2011 and the OECD Test Guideline 408. The results obtained show that the MON810 maize at a level of up to 33 % in the diet did not induce adverse effects in male and female Wistar Han RCC rats after subchronic exposure, independently of the two different genetic backgrounds of the event.

  18. Upper limits to surface-force disturbances on LISA proof masses and the possibility of observing galactic binaries

    SciTech Connect

    Carbone, Ludovico; Ciani, Giacomo; Dolesi, Rita; Hueller, Mauro; Tombolato, David; Vitale, Stefano; Weber, William Joseph; Cavalleri, Antonella

    2007-02-15

    We have measured surface-force noise on a hollow replica of a LISA proof mass surrounded by its capacitive motion sensor. Forces are detected through the torque exerted on the proof mass by means of a torsion pendulum in the 0.1-30 mHz range. The sensor and electronics have the same design as for the flight hardware, including 4 mm gaps around the proof mass. The measured upper limit for forces would allow detection of a number of galactic binaries signals with signal-to-noise ratio up to {approx_equal}40 for 1 yr integration. We also discuss how LISA Pathfinder will substantially improve this limit, approaching the LISA performance.

  19. How states of mind change in psychotherapy: an intensive case analysis of Lisa's case using the Grid of Problematic States.

    PubMed

    Nicolo, Giuseppe; Dimaggio, Giancarlo; Procacci, Michele; Semerari, Antonio; Carcione, Antonino; Pedone, Roberto

    2008-11-01

    This study uses the Grid of Problematic States (GPS) to examine Lisa's case, one of the most successful in the York Psychotherapy Depression Project. This study tried to assess whether the contents of mental experience form stable clusters consistent with a diagnosis of depression. It was possible with the GPS to pinpoint problematic states typical of depression and trace the transitional states occurring in Lisa between two different mental states: depressive and well-being. The GPS analysis suggested that the treatment successfully managed to deal with symptoms and to change the patient's thought themes and emotions. At the end of treatment, Lisa was less sad and displayed some anger, and a state of being nurtured emerged.

  20. Science with the space-based interferometer eLISA. II: gravitational waves from cosmological phase transitions

    SciTech Connect

    Caprini, Chiara; Hindmarsh, Mark; Huber, Stephan; No, Jose Miguel E-mail: S.Huber@sussex.ac.uk; and others

    2016-04-01

    We investigate the potential for the eLISA space-based interferometer to detect the stochastic gravitational wave background produced by strong first-order cosmological phase transitions. We discuss the resulting contributions from bubble collisions, magnetohydrodynamic turbulence, and sound waves to the stochastic background, and estimate the total corresponding signal predicted in gravitational waves. The projected sensitivity of eLISA to cosmological phase transitions is computed in a model-independent way for various detector designs and configurations. By applying these results to several specific models, we demonstrate that eLISA is able to probe many well-motivated scenarios beyond the Standard Model of particle physics predicting strong first-order cosmological phase transitions in the early Universe.

  1. Lightweight Innovative Solar Array (LISA): Providing Higher Power to Small Spacecraft

    NASA Technical Reports Server (NTRS)

    Johnson, Les; Carr, John; Fabisinski, Leo; Russell,Tiffany; Smith, Leigh

    2015-01-01

    Affordable and convenient access to electrical power is essential for all spacecraft and is a critical design driver for the next generation of smallsats, including cubesats, which are currently extremely power limited. The Lightweight Innovative Solar Array (LISA), a concept designed, prototyped, and tested at the NASA Marshall Space Flight Center (MSFC) in Huntsville, Alabama provides an affordable, lightweight, scalable, and easily manufactured approach for power generation in space. This flexible technology has many wide-ranging applications from serving small satellites to providing abundant power to large spacecraft in GEO and beyond. By using very thin, ultra-flexible solar arrays adhered to an inflatable structure, a large area (and thus large amount of power) can be folded and packaged into a relatively small volume. The LISA array comprises a launch-stowed, orbit-deployed structure on which lightweight photovoltaic devices and, potentially, transceiver elements are embedded. The system will provide a 2.5 to 5 fold increase in specific power generation (Watts/kilogram) coupled with a >2x enhancement of stowed volume (Watts/cubic-meter) and a decrease in cost (dollars/Watt) when compared to state-of-the-art solar arrays.

  2. Rapid, automated, parallel quantitative immunoassays using highly integrated microfluidics and AlphaLISA

    NASA Astrophysics Data System (ADS)

    TakYu, Zeta; Guan, Huijiao; Ki Cheung, Mei; McHugh, Walker M.; Cornell, Timothy T.; Shanley, Thomas P.; Kurabayashi, Katsuo; Fu, Jianping

    2015-06-01

    Immunoassays represent one of the most popular analytical methods for detection and quantification of biomolecules. However, conventional immunoassays such as ELISA and flow cytometry, even though providing high sensitivity and specificity and multiplexing capability, can be labor-intensive and prone to human error, making them unsuitable for standardized clinical diagnoses. Using a commercialized no-wash, homogeneous immunoassay technology (‘AlphaLISA’) in conjunction with integrated microfluidics, herein we developed a microfluidic immunoassay chip capable of rapid, automated, parallel immunoassays of microliter quantities of samples. Operation of the microfluidic immunoassay chip entailed rapid mixing and conjugation of AlphaLISA components with target analytes before quantitative imaging for analyte detections in up to eight samples simultaneously. Aspects such as fluid handling and operation, surface passivation, imaging uniformity, and detection sensitivity of the microfluidic immunoassay chip using AlphaLISA were investigated. The microfluidic immunoassay chip could detect one target analyte simultaneously for up to eight samples in 45 min with a limit of detection down to 10 pg mL-1. The microfluidic immunoassay chip was further utilized for functional immunophenotyping to examine cytokine secretion from human immune cells stimulated ex vivo. Together, the microfluidic immunoassay chip provides a promising high-throughput, high-content platform for rapid, automated, parallel quantitative immunosensing applications.

  3. Rapid, automated, parallel quantitative immunoassays using highly integrated microfluidics and AlphaLISA

    PubMed Central

    Tak For Yu, Zeta; Guan, Huijiao; Ki Cheung, Mei; McHugh, Walker M.; Cornell, Timothy T.; Shanley, Thomas P.; Kurabayashi, Katsuo; Fu, Jianping

    2015-01-01

    Immunoassays represent one of the most popular analytical methods for detection and quantification of biomolecules. However, conventional immunoassays such as ELISA and flow cytometry, even though providing high sensitivity and specificity and multiplexing capability, can be labor-intensive and prone to human error, making them unsuitable for standardized clinical diagnoses. Using a commercialized no-wash, homogeneous immunoassay technology (‘AlphaLISA’) in conjunction with integrated microfluidics, herein we developed a microfluidic immunoassay chip capable of rapid, automated, parallel immunoassays of microliter quantities of samples. Operation of the microfluidic immunoassay chip entailed rapid mixing and conjugation of AlphaLISA components with target analytes before quantitative imaging for analyte detections in up to eight samples simultaneously. Aspects such as fluid handling and operation, surface passivation, imaging uniformity, and detection sensitivity of the microfluidic immunoassay chip using AlphaLISA were investigated. The microfluidic immunoassay chip could detect one target analyte simultaneously for up to eight samples in 45 min with a limit of detection down to 10 pg mL−1. The microfluidic immunoassay chip was further utilized for functional immunophenotyping to examine cytokine secretion from human immune cells stimulated ex vivo. Together, the microfluidic immunoassay chip provides a promising high-throughput, high-content platform for rapid, automated, parallel quantitative immunosensing applications. PMID:26074253

  4. Coupling characterization and noise studies of the optical metrology system onboard the LISA Pathfinder mission.

    PubMed

    Hechenblaikner, Gerald; Gerndt, Rüdiger; Johann, Ulrich; Luetzow-Wentzky, Peter; Wand, Vinzenz; Audley, Heather; Danzmann, Karsten; Garcia-Marin, Antonio; Heinzel, Gerhard; Nofrarias, Miquel; Steier, Frank

    2010-10-10

    We describe the first investigations of the complete engineering model of the optical metrology system (OMS), a key subsystem of the LISA Pathfinder science mission to space. The latter itself is a technological precursor mission to LISA, a spaceborne gravitational wave detector. At its core, the OMS consists of four heterodyne Mach-Zehnder interferometers, a highly stable laser with an external modulator, and a phase meter. It is designed to monitor and track the longitudinal motion and attitude of two floating test masses in the optical reference frame with (relative) precision in the picometer and nanorad range, respectively. We analyze sensor signal correlations and determine a physical sensor noise limit. The coupling parameters between motional degrees of freedom and interferometer signals are analytically derived and compared to measurements. We also measure adverse cross-coupling effects originating from system imperfections and limitations and describe algorithmic mitigation techniques to overcome some of them. Their impact on system performance is analyzed within the context of the Pathfinder mission.

  5. Constraints on LISA Pathfinder’s self-gravity: design requirements, estimates and testing procedures

    NASA Astrophysics Data System (ADS)

    Armano, M.; Audley, H.; Auger, G.; Baird, J.; Binetruy, P.; Born, M.; Bortoluzzi, D.; Brandt, N.; Bursi, A.; Caleno, M.; Cavalleri, A.; Cesarini, A.; Cruise, M.; Danzmann, K.; de Deus Silva, M.; Desiderio, D.; Piersanti, E.; Diepholz, I.; Dolesi, R.; Dunbar, N.; Ferraioli, L.; Ferroni, V.; Fitzsimons, E.; Flatscher, R.; Freschi, M.; Gallegos, J.; García Marirrodriga, C.; Gerndt, R.; Gesa, L.; Gibert, F.; Giardini, D.; Giusteri, R.; Grimani, C.; Grzymisch, J.; Harrison, I.; Heinzel, G.; Hewitson, M.; Hollington, D.; Hueller, M.; Huesler, J.; Inchauspé, H.; Jennrich, O.; Jetzer, P.; Johlander, B.; Karnesis, N.; Kaune, B.; Korsakova, N.; Killow, C.; Lloro, I.; Liu, L.; López-Zaragoza, J. P.; Maarschalkerweerd, R.; Madden, S.; Mance, D.; Martín, V.; Martin-Polo, L.; Martino, J.; Martin-Porqueras, F.; Mateos, I.; McNamara, P. W.; Mendes, J.; Mendes, L.; Moroni, A.; Nofrarias, M.; Paczkowski, S.; Perreur-Lloyd, M.; Petiteau, A.; Pivato, P.; Plagnol, E.; Prat, P.; Ragnit, U.; Ramos-Castro, J.; Reiche, J.; Romera Perez, J. A.; Robertson, D.; Rozemeijer, H.; Rivas, F.; Russano, G.; Sarra, P.; Schleicher, A.; Slutsky, J.; Sopuerta, C. F.; Sumner, T.; Texier, D.; Thorpe, J. I.; Tomlinson, R.; Trenkel, C.; Vetrugno, D.; Vitale, S.; Wanner, G.; Ward, H.; Warren, C.; Wass, P. J.; Wealthy, D.; Weber, W. J.; Wittchen, A.; Zanoni, C.; Ziegler, T.; Zweifel, P.

    2016-12-01

    LISA Pathfinder satellite was launched on 3 December 2015 toward the Sun-Earth first Lagrangian point (L1) where the LISA Technology Package (LTP), which is the main science payload, will be tested. LTP achieves measurements of differential acceleration of free-falling test masses (TMs) with sensitivity below 3× {10}-14 {{m}} {{{s}}}-2 {{Hz}}-1/2 within the 1-30 mHz frequency band in one-dimension. The spacecraft itself is responsible for the dominant differential gravitational field acting on the two TMs. Such a force interaction could contribute a significant amount of noise and thus threaten the achievement of the targeted free-fall level. We prevented this by balancing the gravitational forces to the sub nm s-2 level, guided by a protocol based on measurements of the position and the mass of all parts that constitute the satellite, via finite element calculation tool estimates. In this paper, we will introduce the gravitational balance requirements and design, and then discuss our predictions for the balance that will be achieved in flight.

  6. A torsion pendulum test of the Lisa Pathfinder free-fall mode

    NASA Astrophysics Data System (ADS)

    Russano, Giuliana; Dolesi, Rita; Cavalleri, Antonella; Hueller, Mauro; Vitale, Stefano; Weber, William Joseph; Tu, HaiBo

    The LISA Pathfinder geodesic explorer mission for gravitational wave astronomy aims to demonstrate the proof of a low acceleration noise level. The relative acceleration between two test masses free falling in orbit is perturbed by the presence of a larger constant relative acceleration that must be actively compensated in order to keep the test particles centered inside an orbiting apparatus. The actuation force applied to compensate this effect introduces a dominant source of force noise. To suppress this noise source, a “free-fall” actuation control scheme has been designed: actuation is limited to brief impulses, with test masses in free fall in between two “kicks”, with this actuation-free motion then analyzed for the remaining sources of acceleration ultra noise. In this work, we will discuss and present preliminary data for an on-ground torsion pendulum experiment to test this technique, and the associated analysis algorithms, at a level nearing the sub-femto-g/sqrt(Hz) performance required for LISA Pathfinder.

  7. CONSTRAINING THE DARK ENERGY EQUATION OF STATE USING LISA OBSERVATIONS OF SPINNING MASSIVE BLACK HOLE BINARIES

    SciTech Connect

    Petiteau, Antoine; Babak, Stanislav; Sesana, Alberto

    2011-05-10

    Gravitational wave (GW) signals from coalescing massive black hole (MBH) binaries could be used as standard sirens to measure cosmological parameters. The future space-based GW observatory Laser Interferometer Space Antenna (LISA) will detect up to a hundred of those events, providing very accurate measurements of their luminosity distances. To constrain the cosmological parameters, we also need to measure the redshift of the galaxy (or cluster of galaxies) hosting the merger. This requires the identification of a distinctive electromagnetic event associated with the binary coalescence. However, putative electromagnetic signatures may be too weak to be observed. Instead, we study here the possibility of constraining the cosmological parameters by enforcing statistical consistency between all the possible hosts detected within the measurement error box of a few dozen of low-redshift (z < 3) events. We construct MBH populations using merger tree realizations of the dark matter hierarchy in a {Lambda}CDM universe, and we use data from the Millennium simulation to model the galaxy distribution in the LISA error box. We show that, assuming that all the other cosmological parameters are known, the parameter w describing the dark energy equation of state can be constrained to a 4%-8% level (2{sigma} error), competitive with current uncertainties obtained by type Ia supernovae measurements, providing an independent test of our cosmological model.

  8. Constraining the Dark Energy Equation of State Using LISA Observations of Spinning Massive Black Hole Binaries

    NASA Astrophysics Data System (ADS)

    Petiteau, Antoine; Babak, Stanislav; Sesana, Alberto

    2011-05-01

    Gravitational wave (GW) signals from coalescing massive black hole (MBH) binaries could be used as standard sirens to measure cosmological parameters. The future space-based GW observatory Laser Interferometer Space Antenna (LISA) will detect up to a hundred of those events, providing very accurate measurements of their luminosity distances. To constrain the cosmological parameters, we also need to measure the redshift of the galaxy (or cluster of galaxies) hosting the merger. This requires the identification of a distinctive electromagnetic event associated with the binary coalescence. However, putative electromagnetic signatures may be too weak to be observed. Instead, we study here the possibility of constraining the cosmological parameters by enforcing statistical consistency between all the possible hosts detected within the measurement error box of a few dozen of low-redshift (z < 3) events. We construct MBH populations using merger tree realizations of the dark matter hierarchy in a ΛCDM universe, and we use data from the Millennium simulation to model the galaxy distribution in the LISA error box. We show that, assuming that all the other cosmological parameters are known, the parameter w describing the dark energy equation of state can be constrained to a 4%-8% level (2σ error), competitive with current uncertainties obtained by type Ia supernovae measurements, providing an independent test of our cosmological model.

  9. Development of a Micro-Thruster Test Facility which fulfils the LISA requirements

    NASA Astrophysics Data System (ADS)

    Hey, Franz Georg; Keller, A.; Johann, U.; Braxmaier, C.; Tajmar, M.; Fitzsimons, E.; Weise, D.

    2015-05-01

    In the context of investigations for a sufficient attitude control thruster for LISA, we have developed a thruster test facility which consists of a highly precise thrust balance coupled with plasma diagnostics. In parallel to the test facility development, investigations to downscale a High Efficiency Multistage Plasma Thruster (HEMP-T) are also being carried out. The thruster has been used to demonstrate the measurement capabilities of the facility. The setup allows a parallel operation of all instruments and can also be used for other types of μN propulsion systems including cold gas thrusters. The thrust balance consists of two pendulums. As read out a heterodyne laser interferometer is used. Differential wave front sensing (DWS) enables the measurement of the pendulum tilt which, via suitable calibration using an electrostatic comb, can be converted to a thrust. The whole setup is a symmetric configuration enabling a common-mode rejection of the dominant noise sources (e.g. seismic noise etc.). The thrust balance has a demonstrated precision of 0.1 μN. Based on our unique design, this precision can be attained down to 10-3 Hz. Thus, the measurement setup is especially suitable for characterising the thrust noise of potential eLISA propulsion candidates. We give an overview of the design, the present performance and the future plans.

  10. Improved analytic extreme-mass-ratio inspiral model for scoping out eLISA data analysis

    NASA Astrophysics Data System (ADS)

    Chua, Alvin J. K.; Gair, Jonathan R.

    2015-12-01

    The space-based gravitational-wave detector eLISA has been selected as the ESA L3 mission, and the mission design will be finalized by the end of this decade. To prepare for mission formulation over the next few years, several outstanding and urgent questions in data analysis will be addressed using mock data challenges, informed by instrument measurements from the LISA Pathfinder satellite launching at the end of 2015. These data challenges will require accurate and computationally affordable waveform models for anticipated sources such as the extreme-mass-ratio inspirals (EMRIs) of stellar-mass compact objects into massive black holes. Previous data challenges have made use of the well-known analytic EMRI waveforms of Barack and Cutler, which are extremely quick to generate but dephase relative to more accurate waveforms within hours, due to their mismatched radial, polar and azimuthal frequencies. In this paper, we describe an augmented Barack-Cutler model that uses a frequency map to the correct Kerr frequencies, along with updated evolution equations and a simple fit to a more accurate model. The augmented waveforms stay in phase for months and may be generated with virtually no additional computational cost.

  11. High-stability temperature control for ST-7/LISA Pathfinder gravitational reference sensor ground verification testing

    NASA Astrophysics Data System (ADS)

    Higuchi, S.; Allen, G.; Bencze, W.; Byer, R.; Dang, A.; DeBra, D. B.; Lauben, D.; Dorlybounxou, S.; Hanson, J.; Ho, L.; Huffman, G.; Sabur, F.; Sun, K.; Tavernetti, R.; Rolih, L.; Van Patten, R.; Wallace, J.; Williams, S.

    2006-03-01

    This article demonstrates experimental results of a thermal control system developed for ST-7 gravitational reference sensor (GRS) ground verification testing which provides thermal stability δT < 1 mK/surdHz to f < 0.1 mHz, and which by extension is suitable for in-flight thermal control of the LISA spacecraft to compensate solar irradiate 1/f fluctuations. Although for ground testing these specifications can be met fairly readily with sufficient insulation and thermal mass, in contrast, for spacecraft the very limited thermal mass calls for an active control system which can simultaneously meet disturbance rejection and stability requirements in the presence of long time delay; a considerable design challenge. Simple control laws presently provide ~ 1mK/surdHz for >24 hours. Continuing development of a model predictive feedforward control algorithm will extend performance to <1 mK/surdHz at f < 0.01 mHz and possibly lower, extending LISA coverage of super massive black hole mergers.

  12. Biomedical Challenges Presented by the American Indian, Proceedings of the Special Session of the PAHO Advisory Committee on Medical Research (7th, Washington, D.C., June 25, 1968).

    ERIC Educational Resources Information Center

    Pan American Health Organization, Washington, DC.

    At each meeting of the Pan American Health Organization Advisory Committee on Medical Research, a special 1-day session is held on a topic chosen by the committee as being of particular interest. At the 7th meeting, which convened in June of 1968 in Washington, D.C., the session surveyed the origin, present distribution, and principal biological…

  13. Putting 'international' back in IPEC.

    SciTech Connect

    Veil, J. A.

    2000-10-27

    During the previous six annual sessions of the International Petroleum Environmental Conference (IPEC), little attention has been given to international issues. Although the US is clearly a leader in oil field research and regulatory development information is available on interesting projects throughout the world Many participants in IPEC have little exposure to international oil and gas environmental problems and solutions. Beginning with the 7th IPEC, a stronger effort is being made to include international issues in the confidence. This paper describes some of the author's experiences in working with international oil and gas environmental issues in North America, Latin America, Europe, and Asia. Among the topics to be discussed are the issues that developing oil and gas-producing nations face and the need for sensitivity to other nation's cultures and legal systems.

  14. Cornelia de Lange syndrome and molecular implications of the cohesin complex: Abstracts from the 7th biennial scientific and educational symposium 2016.

    PubMed

    Kline, Antonie D; Krantz, Ian D; Deardorff, Matthew A; Shirahige, Katsuhiko; Dorsett, Dale; Gerton, Jennifer L; Wu, Meng; Mehta, Devanshi; Mills, Jason A; Carrico, Cheri S; Noon, Sarah; Herrera, Pamela S; Horsfield, Julia A; Bettale, Chiara; Morgan, Jeremy; Huisman, Sylvia A; Moss, Jo; McCleery, Joseph; Grados, Marco; Hansen, Blake D; Srivastava, Siddharth; Taylor-Snell, Emily; Kerr, Lynne M; Katz, Olivia; Calof, Anne L; Musio, Antonio; Egense, Alena; Haaland, Richard E

    2017-02-12

    Cornelia de Lange Syndrome (CdLS) is due to mutations in the genes for the structural and regulatory proteins that make up the cohesin complex, and is considered a cohesinopathy disorder or, more recently, a transcriptomopathy. New phenotypes have been recognized in this expanding field. There are multiple clinical issues facing individuals with all forms of CdLS, particularly in the neurodevelopmental system, but also gastrointestinal, cardiac, and musculoskeletal. Aspects of developmental and cell biology have found common endpoints in the biology of the cohesin complex, with improved understanding of the mechanisms, easier diagnostic tests, and the possibility of potential therapeutics, all major clinical implications for the individual with CdLS. The following abstracts are the presentations from the 7th Cornelia de Lange Syndrome Scientific and Educational Symposium, June 22-23, 2016, in Orlando, FL, in conjunction with the Cornelia de Lange Syndrome Foundation National Meeting. In addition to the scientific and clinical discussions, there were talks related to practical aspects of behavior including autism, transitions, communication, access to medical care, and databases. At the end of the symposium, a panel was held, which included several parents, affected individuals and genetic counselors, and discussed the greatest challenges in life and how this information can assist in guiding future research. The Research Committee of the CdLS Foundation organizes this meeting, reviews, and accepts abstracts, and subsequently disseminates the information to the families through members of the Clinical Advisory Board and publications. AMA CME credits were provided by Greater Baltimore Medical Center, Baltimore, MD.

  15. Trends of violence among 7th, 8th and 9th grade students in the state of Lara, Venezuela: The Global School Health Survey 2004 and 2008

    PubMed Central

    2011-01-01

    Background Violence by young people is one of the most visible forms of violence and contributes greatly to the global burden of premature death, injury and disability. Methods The Global School-based Student Health Survey (GSHS), State of Lara, Venezuela (GSHS-Lara) is a school-based surveillance system. It comprises a repeated, cross-sectional, self-administered survey drawn from a representative sample of 7th to 9th grade students, performed in the school years 2003-2004 (GSHS-Lara 2004) and 2007-2008 (GSHS-Lara 2008). It explores, among other things, a general violence indicator such as school absenteeism due to feeling unsafe at school or on the way to or from school for any reason; and more specific indicators of violence such as robbery, bullying, physical fights and use of weapons, as well as exposure to lectures on how to prevent violence. Results are given in terms of prevalence percentage. Results Absenteeism doubled between the two study periods (10.8% to 20.8%). The number of students that were a victim of robbery remained high and without change both outside (14.2% and 14.8%) and inside school (21.7% and 22.0%). The number of victims of bullying was high and increasing (33.4% and 43.6%). Bullying associated with being physically attacked decreased (18.5% to 14.3%). Physical attacks without active participation and not associated with bullying were frequent (21.5%). Physical fighting with active participation prevalence remained high and without change (27.5% and 28.2%). Carrying a weapon almost doubled (4.3% to 7.1%). Less than 65% reported classes for violence prevention. Conclusions The GSHS-Lara shows that violence is an important public health problem that needs to be addressed by the community and its authorities. PMID:22958602

  16. Novel C617Y mutation in the 7th transmembrane segment of luteinizing hormone/choriogonadotropin receptor in a Japanese boy with peripheral precocious puberty.

    PubMed

    Nagasaki, Keisuke; Katsumata, Noriyuki; Ogawa, Yohei; Kikuchi, Toru; Uchiyama, Makoto

    2010-01-01

    Testotoxicosis, also known as familial male-limited precocious puberty, is an autosomal dominant form of gonadotropin-independent precocious puberty caused by heterozygous constitutively activating mutations of the LHCGR gene encoding the luteinizing hormone/choriogonadotropin receptor (LH/CGR). The patient is an 8-year-old boy who started to develop pubic hair and penile enlargement at 6 years of age. The patient had elevated serum testosterone levels, but initially exhibited a prepubertal response of gonadotropins to GnRH, which was followed by central activation of the hypothalamo-pituitary-gonadal axis. The father reported having experienced precocious puberty, and is 158 cm tall. There is no history of short stature and precocious puberty in the family except for the father. The LHCGR gene was analyzed by direct DNA sequencing of amplified PCR products from the patient and his parents. The wild-type and mutant LH/CGRs were transiently expressed in COS-1 cells and cAMP levels in the cells were determined with or without hCG stimulation. Genetic analysis revealed a novel C617Y mutation of the LHCGR gene in the patient and his mother, while his father had no mutations. Functional expression study demonstrated around 15% increase in the basal intracellular cAMP level in cells expressing the mutant LH/CGR compared with that in cells expressing the wild-type receptor. We have reported the first missense C617Y mutation located in the 7th transmembrane segment of LH/CGR causing testotoxicosis. The modest phenotype of our patient may be explained, at least in part, by the modest increase in the intracellular cAMP level caused by the C617Y mutation.

  17. Identification, Geochemical Characterisation and Significance of Bitumen among the Grave Goods of the 7th Century Mound 1 Ship-Burial at Sutton Hoo (Suffolk, UK)

    PubMed Central

    Bowden, Stephen A.; Hacke, Marei; Parnell, John

    2016-01-01

    The 7th century ship-burial at Sutton Hoo is famous for the spectacular treasure discovered when it was first excavated in 1939. The finds include gold and garnet jewellery, silverware, coins and ceremonial armour of broad geographical provenance which make a vital contribution to understanding the political landscape of early medieval Northern Europe. Fragments of black organic material found scattered within the burial were originally identified as ‘Stockholm Tar’ and linked to waterproofing and maintenance of the ship. Here we present new scientific analyses undertaken to re-evaluate the nature and origin of these materials, leading to the identification of a previously unrecognised prestige material among the treasure: bitumen from the Middle East. Whether the bitumen was gifted as diplomatic gesture or acquired through trading links, its presence in the burial attests to the far-reaching network within which the elite of the region operated at this time. If the bitumen was worked into objects, either alone or in composite with other materials, then their significance within the burial would certainly have been strongly linked to their form or purpose. But the novelty of the material itself may have added to the exotic appeal. Archaeological finds of bitumen from this and earlier periods in Britain are extremely rare, despite the abundance of natural sources of bitumen within Great Britain. This find provides the first material evidence indicating that the extensively exploited Middle Eastern bitumen sources were traded northward beyond the Mediterranean to reach northern Europe and the British Isles. PMID:27906999

  18. Process evaluation for a school-based physical activity intervention for 6th- and 7th-grade boys: reach, dose, and fidelity.

    PubMed

    Robbins, Lorraine B; Pfeiffer, Karin Allor; Wesolek, Stacey M; Lo, Yun-Jia

    2014-02-01

    The purpose was to evaluate the reach, dose, and fidelity of Guys Only Activity for Life (G.O.A.L.), a 7-week pilot intervention conducted from February to March 2011 to increase 6th and 7th grade boys' moderate-to-vigorous physical activity (MVPA). One middle school was randomly assigned to the G.O.A.L. intervention and another from the same urban school district in the Midwestern U.S. to a comparison condition. Thirty boys, ages 10-14 years, participated in each school. The intervention, guided by the Health Promotion Model (HPM) and Self-Determination Theory (SDT), consisted of a 90-min after-school physical activity club 4 days/week and one motivational interviewing session with a registered (school) nurse. Data were gathered via attendance records, club observations, heart rate monitors, audio-taping of motivational interviewing sessions, and surveys. On average boys attended the club 2.11 days/week (SD=.86). A trained independent process evaluator reported that the physical activity club instructors provided the boys with the opportunity for a mean of 25.8 min/day of MVPA. Using a four-point Likert scale (1=disagree a lot; 4=agree a lot), the process evaluator perceived that the club was delivered with high fidelity and adherence to the underlying theories (M=3.48; SD=0.39). Sessions with the nurse lasted an average of 13 min, 29 s. All boys attended. Two trained independent coders indicated that the nurse demonstrated at least beginning proficiency for all tasks associated with motivational interviewing, with the exception of using sufficient open- as opposed to closed-ended questions and reflections compared to questions. Fidelity related to session delivery and adherence to the theories was high (M=3.83; SD=0.19). The process evaluation data indicated that strategies are needed to increase attendance and boys' MVPA during the club time.

  19. Report of the 7th meeting on Evaluation of Pandemic Influenza Vaccines in Clinical Trials, World Health Organization, Geneva, 17-18 February 2011.

    PubMed

    Girard, Marc P; Katz, Jacqueline M; Pervikov, Yuri; Hombach, Joachim; Tam, John S

    2011-10-13

    On February 17-18, 2011, the World Health Organization convened the 7th meeting on "The Evaluation of Pandemic Influenza Vaccines in Clinical Trials" to review the progress made on pandemic A (H1N1) 2009 vaccines and the evaluation of their effectiveness in the field, especially in children less than 3 years of age and in pregnant women. Other topics to be addressed included a comparison of egg- and cell culture-based influenza vaccines, technical issues related to vaccine strain development and vaccine potency, and the status of development of prototype influenza vaccines using new technologies. Pandemic A (H1N1) vaccines were safe in young children, pregnant women and immunocompromized individuals. Overall effectiveness of inactivated A (H1N1) vaccines for all ages was found to vary between 72% and 100% in different countries and with different vaccine preparations. Effectiveness of pandemic A (H1N1) 2009 live attenuated vaccine was estimated to be approximately 80% in pediatric populations in the USA. A single dose of inactivated vaccine adjuvanted with AS03, MF59 or AF03 induced protective immunity in young children and pregnant women. However, unadjuvanted vaccines as well as low dose adjuvanted vaccines (1.9 μg HA) required two doses to elicit protective antibody levels in these populations. Clinical trials of influenza vaccines developed using new technologies showed they were well tolerated and induced antibody and/or T cell immune responses to viral proteins. Further studies are warranted to validate novel immunological criteria for evaluation and licensing of such new influenza vaccine concepts. On the regulatory side, work should be undertaken to harmonize the results of serological tests used to evaluate the immunogenicity of traditional influenza vaccines.

  20. LISA-PF radiation monitor performance during the evolution of SEP events for the monitoring of test-mass charging

    NASA Astrophysics Data System (ADS)

    Grimani, C.; Ao, X.; Fabi, M.; Laurenza, M.; Li, G.; Lobo, A.; Mateos, I.; Storini, M.; Verkhoglyadova, O.; Zank, G. P.

    2014-02-01

    Cosmic rays of solar and galactic origin at energies >100 MeV/n charge and induce spurious forces on free-floating test masses on board interferometers devoted to gravitational wave detection in space. LISA Pathfinder (LISA-PF), the technology testing mission for eLISA/NGO, will carry radiation monitors for on board test-mass charging monitoring. We present here the results of a simulation of radiation monitor performance during the evolution of solar energetic particle (SEP) events of different intensity. This simulation was carried out with the Fluka Monte Carlo package by taking into account for the first time both energy and spatial distributions of solar protons for the SEP events of 23 February 1956, 15 November 1960 and 7 May 1978. Input data for the Monte Carlo simulations was inferred from neutron monitor measurements. Conversely, for the SEP event of 13 December 2006 observed by the PAMELA experiment in space, we used the proton pitch angle distribution (PAD) computed from the Particle Acceleration and Transport in the Heliosphere (PATH) code. We plan to adopt this approach at the time of LISA-PF data analysis in order to optimize the correlation between radiation monitor observations and test-mass charging. The results of this work can be extended to the future space interferometers and other space missions carrying instruments for SEP detection.