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Sample records for 800-cdc-info 800-232-4636 tty

  1. Tick-Borne Encephalitis (TBE)

    MedlinePlus

    ... sick sheep (e.g., veterinarians, butchers). In the USA and Russia, another tick-borne flavivirus, Powassan virus, ... OIG 1600 Clifton Road Atlanta , GA 30329-4027 USA 800-CDC-INFO (800-232-4636) , TTY: 888- ...

  2. Middle East Respiratory Syndrome (MERS)

    MedlinePlus

    ... United Kingdom (UK), and United States of America (USA). CDC Commentary: Be on the Lookout for MERS- ... OIG 1600 Clifton Road Atlanta , GA 30329-4027 USA 800-CDC-INFO (800-232-4636) , TTY: 888- ...

  3. Anthrax Vaccine: What You Need to Know

    MedlinePlus

    ... I learn more? • Ask your doctor. • Contact the Centers for Disease Control and Prevention (CDC): - Call 1-800-232-4636 ( 1-800-CDC-INFO ) - Visit the CDC’s website at http: / / emergency. cdc. gov/ agent/ anthrax/ • Contact the U.S. Department of Defense (DoD): - Call 1-877-438-8222 - Visit the ...

  4. Saccharomyces cerevisiae Tti2 Regulates PIKK Proteins and Stress Response

    PubMed Central

    Hoffman, Kyle S.; Duennwald, Martin L.; Karagiannis, Jim; Genereaux, Julie; McCarton, Alexander S.; Brandl, Christopher J.

    2016-01-01

    The TTT complex is composed of the three essential proteins Tel2, Tti1, and Tti2. The complex is required to maintain steady state levels of phosphatidylinositol 3-kinase-related kinase (PIKK) proteins, including mTOR, ATM/Tel1, ATR/Mec1, and TRRAP/Tra1, all of which serve as regulators of critical cell signaling pathways. Due to their association with heat shock proteins, and with newly synthesized PIKK peptides, components of the TTT complex may act as cochaperones. Here, we analyze the consequences of depleting the cellular level of Tti2 in Saccharomyces cerevisiae. We show that yeast expressing low levels of Tti2 are viable under optimal growth conditions, but the cells are sensitive to a number of stress conditions that involve PIKK pathways. In agreement with this, depleting Tti2 levels decreased expression of Tra1, Mec1, and Tor1, affected their localization and inhibited the stress responses in which these molecules are involved. Tti2 expression was not increased during heat shock, implying that it does not play a general role in the heat shock response. However, steady state levels of Hsp42 increase when Tti2 is depleted, and tti2L187P has a synthetic interaction with exon 1 of the human Huntingtin gene containing a 103 residue polyQ sequence, suggesting a general role in protein quality control. We also find that overexpressing Hsp90 or its cochaperones is synthetic lethal when Tti2 is depleted, an effect possibly due to imbalanced stoichiometry of a complex required for PIKK assembly. These results indicate that Tti2 does not act as a general chaperone, but may have a specialized function in PIKK folding and/or complex assembly. PMID:27172216

  5. Using a TTY to contact clinical graduate programs.

    PubMed

    Olkin, R; Shafton-Bias, E

    1997-10-01

    This study investigated accessibility of 177 APA-accredited clinical and counseling programs to deaf applicants via TTY phone lines, what happened when we called these numbers, and where these phone lines connected. We were able to obtain TTY phone numbers for 135 schools, of which we could successfully reach 86 schools using a TTY alone. Most of these lines (60%) were connected to campus disabled student services, and none connected directly to the APA-accredited programs or the departments in which they were housed. Comments from university personnel underscore the difficulties facing deaf applicants. We argue that the difficulties deaf applicants encounter when trying to contact programs constitute significant barriers to the application process. We give six specific recommendations for expanding access to programs.

  6. 78 FR 15682 - Notification of Proposed Production Activity TTI, Inc.; Subzone 196A (Electromechanical and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-12

    ... Foreign-Trade Zones Board Notification of Proposed Production Activity TTI, Inc.; Subzone 196A (Electromechanical and Circuit Protection Devices Production/ Kitting); Fort Worth, TX TTI, Inc. (TTI), operator of Subzone 196A, submitted a notification of proposed production activity for its facilities located in...

  7. 78 FR 37203 - Authorization of Production Activity; Subzone 196A; TTI, Inc. (Electromechanical and Circuit...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-20

    ... Foreign-Trade Zones Board Authorization of Production Activity; Subzone 196A; TTI, Inc. (Electromechanical and Circuit Protection Devices Production/Kitting); Fort Worth, Texas On February 13, 2013, TTI, Inc. submitted a notification of proposed production activity to the Foreign-Trade Zones (FTZ) Board for...

  8. 49 CFR 571.5 - Matter incorporated by reference.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Services, Hyattsville, MD 20782. Phone: 1-800-232-4636; Web: http://www.cdc.gov/nchs National Highway..., Warrendale, Pennsylvania 15096. Phone: 1-724-776-4841; Web: http://www.sae.org Society of...

  9. 49 CFR 571.5 - Matter incorporated by reference

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Control (CDC), National Division for Health Statistics, Division of Data Services, Hyattsville, MD 20782. Phone: 1-800-232-4636; Web: http://www.cdc.gov/nchs “Weight, Height, and Selected Body Dimensions...

  10. Tdap Vaccine (Tetanus, Diphtheria and Pertussis): What You Need to Know

    MedlinePlus

    ... United States today. It can cause a thick coating to form in the back of the throat. • ... state health department. • Contact the Centers for Disease Control and Prevention (CDC): - Call 1-800-232-4636 ( ...

  11. Td Vaccine (Tetanus and Diphtheria): What You Need to Know

    MedlinePlus

    ... best medical care. DIPHTHERIA can cause a thick coating to form in the back of the throat. • ... state health department. • Contact the Centers for Disease Control and Prevention (CDC): - Call 1-800-232-4636 ( ...

  12. Applicability of a microbial Time Temperature Indicator (TTI) for monitoring spoilage of modified atmosphere packed minced meat.

    PubMed

    Vaikousi, Hariklia; Biliaderis, Costas G; Koutsoumanis, Konstantinos P

    2009-08-15

    The applicability of a microbial Time Temperature Indicator (TTI) prototype, based on the growth and metabolic activity of a Lactobacillus sakei strain developed in a previous study, in monitoring quality of modified atmosphere packed (MAP) minced beef was evaluated at conditions simulating the chill chain. At all storage temperatures examined (0, 5, 10, 15 degrees C), the results showed that lactic acid bacteria (LAB) were the dominant bacteria and can be used as a good spoilage index of MAP minced beef. The end of product's shelf life as revealed by the sensory evaluation coincided with a LAB population level of 7 log(10) CFU/g. For all temperatures tested, the growth of L. sakei in the TTI resembled closely the growth of LAB in the meat product, with similar temperature dependence of the micro(max) and thus similar activation energy values calculated as 111.90 and 106.90 kJ/mol, for the two systems, respectively. In addition, the end point of TTI colour change coincided with the time of sensory rejection point of the beef product during its storage under isothermal chilled temperature conditions. The estimated activation energy, E(alpha), values obtained for parameters related to the response of DeltaE (total colour change of the TTI) describing the kinetics of colour change of the TTI during isothermal storage (i.e. the maximum specific rate of DeltaEpsilon evolution curve, micro(DeltaEpsilon), and also the reciprocal of t(i), time at which half of the maximum DeltaEpsilon is reached), were 112.77 and 127.28 kJ/mol, respectively. Finally, the application of the microbial TTI in monitoring the quality deterioration of MAP minced beef due to spoilage was further evaluated under dynamic conditions of storage, using two separate low temperature periodic changing scenarios, resembling the actual conditions occurring in the distribution chill chain. The results showed that the end point of TTI, after storage at those fluctuating temperature conditions, was noted very

  13. Development of Health Education Learning Module in Bac.TSE-LDPE Programme in TTI: Needs Analysis Study

    ERIC Educational Resources Information Center

    Ujang, Alijah; Alias, Norlidah; Siraj, Saedah

    2015-01-01

    This study is to explore the need to develop learning modules of health education for trainee teachers in the Bachelor Of Teaching (Hons)(Special Education-Learning Disabilities For Primary Education) Programme (Bac.TSE-LDPE) in the Teacher Training Institute (TTI). The questionnaire uses the Likert scale with the close ended questions analysed by…

  14. German Deaf People Using Text Communication: Short Message Service, TTY, Relay Services, Fax, and E-Mail

    ERIC Educational Resources Information Center

    Power, Des; Power, Mary R.; Rehling, Bernd

    2007-01-01

    An online survey of German deaf people demonstrated that they use text communication through Short Message Service (SMS), e-mail, fax, and telephone typewriters (TTY) to communicate within communities of deaf and hearing people. SMS is used most, with more than 96% of respondents having access to a mobile phone. Most use is intrinsic and directed…

  15. German deaf people using text communication: short message service, TTY, relay services, fax, and e-mail.

    PubMed

    Power, Des; Power, Mary R; Rehling, Bernd

    2007-01-01

    An online survey of German deaf people demonstrated that they use text communication through Short Message Service (SMS), e-mail, fax, and telephone typewriters (TTY) to communicate within communities of deaf and hearing people. SMS is used most, with more than 96% of respondents having access to a mobile phone. Most use is intrinsic and directed toward sociability (keeping in contact, and making arrangements with friends and family). However, there is some instrumental use (getting tasks or business accomplished, making appointments, and obtaining information). German survey respondents wanted a better relay service, more connectivity among the various technologies, and full interactivity in making calls by any technology. In comparison with an Australian sample, German deaf people could not rely on extensive relay services connecting people with a TTY to hearing telephone subscribers for calls of either a social or business nature.

  16. Evidence for tty Production and Measurement of (σ tt)γ/(σtt)

    DOE PAGES

    Aaltonen, T.

    2011-08-31

    Using data corresponding to 6.0 fb-1 of pp collisions at √s = 1.96 TeV collected by the CDF II detector, we present a cross section measurement of top-quark pair production with an additional radiated photon, ttγ. The events are selected by looking for a lepton (ell), a photon (γ), significant transverse momentum imbalance (ET), large total transverse energy, and three or more jets, with at least one identified as containing a b quark (b). The ttγ sample requires the photon to have 10 GeV or more of transverse energy, and to be in the central region. Using an event selectionmore » optimized for the ttγ candidate sample we measure the production cross section of tt (σtt), and the ratio of cross sections of the two samples. Control samples in the dilepton+photon and lepton+photon+ET, channels are constructed to aid in decay product identification and background measurements. We observe 30 ttγ candidate events compared to the standard model expectation of 26.9 ± 3.4 events. We measure the ttγ cross section (σtt) to be 0.18 ± 0.08 pb, and the ratio of σttγ to σtt to be 0.024 ± 0.009. Assuming no tty production, we observe a probability of 0.0015 of the background events alone producing 30 events or more, corresponding to 3.0 standard deviations.« less

  17. Modelling spoilage of fresh turbot and evaluation of a time-temperature integrator (TTI) label under fluctuating temperature.

    PubMed

    Nuin, Maider; Alfaro, Begoña; Cruz, Ziortza; Argarate, Nerea; George, Susie; Le Marc, Yvan; Olley, June; Pin, Carmen

    2008-10-31

    Kinetic models were developed to predict the microbial spoilage and the sensory quality of fresh fish and to evaluate the efficiency of a commercial time-temperature integrator (TTI) label, Fresh Check(R), to monitor shelf life. Farmed turbot (Psetta maxima) samples were packaged in PVC film and stored at 0, 5, 10 and 15 degrees C. Microbial growth and sensory attributes were monitored at regular time intervals. The response of the Fresh Check device was measured at the same temperatures during the storage period. The sensory perception was quantified according to a global sensory indicator obtained by principal component analysis as well as to the Quality Index Method, QIM, as described by Rahman and Olley [Rahman, H.A., Olley, J., 1984. Assessment of sensory techniques for quality assessment of Australian fish. CSIRO Tasmanian Regional Laboratory. Occasional paper n. 8. Available from the Australian Maritime College library. Newnham. Tasmania]. Both methods were found equally valid to monitor the loss of sensory quality. The maximum specific growth rate of spoilage bacteria, the rate of change of the sensory indicators and the rate of change of the colour measurements of the TTI label were modelled as a function of temperature. The temperature had a similar effect on the bacteria, sensory and Fresh Check kinetics. At the time of sensory rejection, the bacterial load was ca. 10(5)-10(6) cfu/g. The end of shelf life indicated by the Fresh Check label was close to the sensory rejection time. The performance of the models was validated under fluctuating temperature conditions by comparing the predicted and measured values for all microbial, sensory and TTI responses. The models have been implemented in a Visual Basic add-in for Excel called "Fish Shelf Life Prediction (FSLP)". This program predicts sensory acceptability and growth of spoilage bacteria in fish and the response of the TTI at constant and fluctuating temperature conditions. The program is freely

  18. Testing treatments interactive (TTi): helping to equip the public to promote better research for better health care.

    PubMed

    Chen, Yaolong; Chalmers, Iain

    2015-05-01

    Testing Treatments is a book written to help everyone understand why testing treatments is so important, why treatment tests have to be fair, and how everyone can help to promote better research for better health care. The book proved to be very popular and its second edition has already been translated into a dozen languages, with more translations in the pipeline. The texts of the original English and all the translations are feely downloadable from Testing Treatments interactive at www.testingtreatments.org. The editors of all the different language websites have established an TTi Editorial Alliance, to share experiences and provide each other with mutual support. The TTi Editorial Alliance seeks to promote a world in which health professionals, patients and the public use reliable research to inform their health decisions. Its missions are (i) To promote a global network, involving members of the public in partnership with professionals, to communicate and discuss basic principles and general knowledge about testing treatments; (ii) to help the public increase critical thinking and skills in accessing, apprehending, appraising and using research evidence; and (iii) to help patients and the public to participate more actively in health research.

  19. Application and validation of the TTI based chill chain management system SMAS (Safety Monitoring and Assurance System) on shelf life optimization of vacuum packed chilled tuna.

    PubMed

    Tsironi, Theofania; Gogou, Eleni; Velliou, Eirini; Taoukis, Petros S

    2008-11-30

    The objective of the study was to establish a validated kinetic model for growth of spoilage bacteria on vacuum packed tuna slices in the temperature range of 0 to 15 degrees C and to evaluate the applicability of the TTI (Time Temperature Integrators) based SMAS (Safety Monitoring and Assurance System) system to improve tuna product quality at the time of consumption in comparison to the conventional First In First Out (FIFO) approach. The overall measurements of total flora and lactic acid bacteria (LAB) on the tuna samples used in a laboratory simulated field test were in close agreement with the predictions of the developed kinetic model. The spoilage profile of the TTI bearing products, handled with SMAS, was improved. Three out of the thirty products that were handled randomly, according to the FIFO approach, were already spoiled at the time of consumption (logN(LAB)>6.5) compared to no spoiled products when handled with the SMAS approach.

  20. Motif of misfit layer compounds (SnS) xTS 2 (T=Ti, V, Nb, Ta) in the matrix of SnS 2

    NASA Astrophysics Data System (ADS)

    Abramov, S. P.

    1999-09-01

    The possibility of T (T=Ti, V, Nb, Ta) insertion in the layer matrix of SnS 2 (when T≪Sn) presents a special case of intercalation for the specific interactions that are inherent in the misfit layer compounds (SnS) xTS 2 ( x≈1). FT Raman spectra of T xSnS 2 (T=Ti, V) with x≪1 testify to the SnS 2 matrix that is invariable with respect to a charge transfer from T to SnS 2 layers as compared with the pristine SnS 2. At the same time the T xSnS 2 structure ( x≪1) taken as a whole has substantial features in the UV-IR spectra as compared with the pristine SnS 2 but is still a semiconductor at least in the case of T=Ti. This points out in the cluster manner of TS 2 insertion in the matrix of SnS 2 with the interactions that are typical of the misfit layer compounds (SnS) xTS 2 in which metallic conductivity occurs in the TS 2 layers.

  1. Tailored and Integrated Web-Based Tools for Improving Psychosocial Outcomes of Cancer Patients: The DoTTI Development Framework

    PubMed Central

    Bryant, Jamie; Sanson-Fisher, Rob; Tzelepis, Flora; Henskens, Frans; Paul, Christine; Stevenson, William

    2014-01-01

    Background Effective communication with cancer patients and their families about their disease, treatment options, and possible outcomes may improve psychosocial outcomes. However, traditional approaches to providing information to patients, including verbal information and written booklets, have a number of shortcomings centered on their limited ability to meet patient preferences and literacy levels. New-generation Web-based technologies offer an innovative and pragmatic solution for overcoming these limitations by providing a platform for interactive information seeking, information sharing, and user-centered tailoring. Objective The primary goal of this paper is to discuss the advantages of comprehensive and iterative Web-based technologies for health information provision and propose a four-phase framework for the development of Web-based information tools. Methods The proposed framework draws on our experience of constructing a Web-based information tool for hematological cancer patients and their families. The framework is based on principles for the development and evaluation of complex interventions and draws on the Agile methodology of software programming that emphasizes collaboration and iteration throughout the development process. Results The DoTTI framework provides a model for a comprehensive and iterative approach to the development of Web-based informational tools for patients. The process involves 4 phases of development: (1) Design and development, (2) Testing early iterations, (3) Testing for effectiveness, and (4) Integration and implementation. At each step, stakeholders (including researchers, clinicians, consumers, and programmers) are engaged in consultations to review progress, provide feedback on versions of the Web-based tool, and based on feedback, determine the appropriate next steps in development. Conclusions This 4-phase framework is evidence-informed and consumer-centered and could be applied widely to develop Web-based programs

  2. Evidence for tty Production and Measurement of (σ tt)γ/(σtt)

    SciTech Connect

    Aaltonen, T.

    2011-08-31

    Using data corresponding to 6.0 fb-1 of pp collisions at √s = 1.96 TeV collected by the CDF II detector, we present a cross section measurement of top-quark pair production with an additional radiated photon, ttγ. The events are selected by looking for a lepton (ell), a photon (γ), significant transverse momentum imbalance (ET), large total transverse energy, and three or more jets, with at least one identified as containing a b quark (b). The ttγ sample requires the photon to have 10 GeV or more of transverse energy, and to be in the central region. Using an event selection optimized for the ttγ candidate sample we measure the production cross section of tt (σtt), and the ratio of cross sections of the two samples. Control samples in the dilepton+photon and lepton+photon+ET, channels are constructed to aid in decay product identification and background measurements. We observe 30 ttγ candidate events compared to the standard model expectation of 26.9 ± 3.4 events. We measure the ttγ cross section (σtt) to be 0.18 ± 0.08 pb, and the ratio of σttγ to σtt to be 0.024 ± 0.009. Assuming no tty production, we observe a probability of 0.0015 of the background events alone producing 30 events or more, corresponding to 3.0 standard deviations.

  3. Hello IM, Goodbye TTY

    ERIC Educational Resources Information Center

    Bell, Lori; Peters, Tom

    2006-01-01

    According to the National Association of the Deaf, there are approximately 28 million deaf and hearing-impaired people in the U.S.--roughly 10 percent of the total population. This hearing-impaired population may be even more isolated than the visually impaired community. Although technology is making it easier for libraries to provide effective…

  4. Sexual Assault

    MedlinePlus

    ... HHS Phone Number: 800-232-4636 Office on Violence Against Women, U.S. Department of Justice Phone Number: 202-514-2000 Loveisrespect.org Phone Number: 866-331-9474 National Center for Victims of Crime Phone Number: 202-467-8700 National Domestic Violence Hotline Phone Number: 800-799-7233 National ...

  5. FASTSAT-HSV01 Synergistic Observations of the Magnetospheric Response During Active Periods: MINI-ME, PISA and TTI

    NASA Technical Reports Server (NTRS)

    Casas, Joseph C.; Collier, Michael R.; Rowland, Douglas E.; Sigwarth, John B.; Boudreaux, Mark E.

    2010-01-01

    potentially contribute to space weather research in a synergistic manner. MINI-ME, a neutral atom imager, will observe the neutral atom inputs to ionospheric heating which can be important during high levels of magnetospheric activity. PISA, a plasma impedance spectrometer, will measure simultaneously the local electron densities and temperatures as well as measure small scale density structure (500 m spatial scale) during these active periods. TTI, a thermospheric imager, will remotely determine the thermospheric temperature response to this magnetospheric activity. Together, these observations will contribute significantly to a comprehensive understanding of the flow of energy through and the response of the storm-time terrestrial magnetosphere.

  6. FASTSAT-HSV01 synergistic observations of the magnetospheric response during active periods: MINI-ME, PISA and TTI

    NASA Astrophysics Data System (ADS)

    Casas, Joseph; Collier, Michael; Rowland, Douglas; Sigwarth, John; Boudreaux, Mark

    potentially contribute to space weather research in a synergistic manner. MINI-ME, a neutral atom imager, will observe the neutral atom inputs to ionospheric heating which can be important during high levels of magnetospheric activity. PISA, a plasma impedance spec-trometer, will measure simultaneously the local electron densities and temperatures as well as measure small scale density structure (500 m spatial scale) during these active periods. TTI, a thermospheric imager, will remotely determine the thermospheric temperature response to this magnetospheric activity. Together, these observations will contribute significantly to a comprehensive understanding of the flow of energy through and the response of the storm-time terrestrial magnetosphere.

  7. Uterine Cancer

    MedlinePlus

    ... most common cancer in women in the United States and it is the most commonly diagnosed gynecologic cancer. Fallopian Tubes Ovaries Uterus Cervix Vagina Vulva www. cdc. gov/ cancer/ knowledge 800-CDC-INFO Inside Knowledge is an initiative ...

  8. About Mumps

    MedlinePlus

    ... Providers Laboratory Testing for Mumps Infection Specimen Collection, Storage, and Shipment Questions and Answers about Lab Testing ... No Fear Act OIG 1600 Clifton Road Atlanta , GA 30329-4027 USA 800-CDC-INFO (800-232- ...

  9. Hyperfine Fields at 51V in Heusler Alloys Co2T1-xVxGa (T{=}Ti, Cr, Mn, Fe) and Estimation of Magnetic Moments of the Constituent Atoms

    NASA Astrophysics Data System (ADS)

    Kawakami, Masayuki; Nagahama, Masatoshi; Satohira, Shin-ichi

    1990-12-01

    The hyperfine fields Hhf in the ferromagnetic alloys Co2T1-xVxGa (T{=}Ti, Cr, Mn, Fe) were measured by NMR spin-echo technique at 4.2 K as a function of x. Hhf(V) on V impurity at b sites (x≃0) was determined to be -41, -40± 2, -15 and -38± 3 kOe for T{=}Ti, Cr, Mn and Fe, respectively. We estimated from these values, assuming V to be non magnetic, the magnetic moments of the atoms in Co2CrGa and Co2FeGa with the use of the measured saturation moments. It was found that for the two alloys the same moments were obtained also from Hhf(Mn) on Mn impurity instead of V by assuming that the magnetic moment of Mn impurity in these alloys is the same as the Mn moment in Co2MnGa. The estimated moments of Cr and Fe were found to be consistent with Hhf(Co).

  10. 77 FR 11547 - Advisory Board on Radiation and Worker Health (ABRWH or Advisory Board), National Institute for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-27

    ... HUMAN SERVICES Centers for Disease Control and Prevention (CDC) Advisory Board on Radiation and Worker...). CONTACT PERSON FOR MORE INFORMATION: Theodore Katz, M.P.A., Executive Secretary, NIOSH, CDC, 1600 Clifton Road, NE., MS E-20, Atlanta, Georgia 30333, Telephone: (513) 533-6800, toll free: 1-800-CDC-INFO,...

  11. Tactical Target Identification (TTI) Laboratory Simulation. Volume I.

    DTIC Science & Technology

    1980-03-01

    was a much more difficult task. Some form of lineal to raster conversion package had to be constructed to allow display of the aircraft files. The image...DX, DY) LVECT is a lineal to raster conversion routine that "draws" a straight line in the graphic buffer between (CX, CY) and (CX+DX, CY+DY). LVECT...are calculated from these values. 3.2.5 VECTOR.FTN The three vector algebra routines UNITV, DOTP and CROSSP are used without change from their RT-1l

  12. T-TY Tank Farm Interim Surface Barrier Demonstration - Vadose Zone Monitoring FY10 Report

    SciTech Connect

    Zhang, Z. F.; Strickland, Christopher E.; Field, Jim G.; Parker, Danny L.

    2011-01-01

    The U.S. Department of Energy’s Office of River Protection has constructed interim surface barriers over a portion of the T and TY tank farms as part of the Interim Surface Barrier Demonstration Project. The interim surface barriers (hereafter referred to as the surface barriers or barriers) are designed to minimize the infiltration of precipitation into the soil zones containing radioactive contaminants and minimize the movement of the contaminants. As part of the demonstration effort, vadose zone moisture is being monitored to assess the effectiveness of the barriers at reducing soil moisture. Solar-powered systems were installed to continuously monitor soil water conditions at four locations in the T (i.e., instrument Nests TA, TB, TC, and TD) and the TY (i.e., instrument Nests TYA and TYB) Farms beneath the barriers and outside the barrier footprint as well as site meteorological conditions. Nests TA and TYA are placed in the area outside the barrier footprint and serve as controls, providing subsurface conditions outside the influence of the surface barriers. Nest TB provides subsurface measurements to assess surface-barrier edge effects. Nests TC, TD, and TYB are used to assess changes in soil-moisture conditions beneath the interim surface barriers.

  13. Simultaneous elastic parameter inversion in 2-D/3-D TTI medium combined later arrival times

    NASA Astrophysics Data System (ADS)

    Bai, Chao-ying; Wang, Tao; Yang, Shang-bei; Li, Xing-wang; Huang, Guo-jiao

    2016-04-01

    Traditional traveltime inversion for anisotropic medium is, in general, based on a "weak" assumption in the anisotropic property, which simplifies both the forward part (ray tracing is performed once only) and the inversion part (a linear inversion solver is possible). But for some real applications, a general (both "weak" and "strong") anisotropic medium should be considered. In such cases, one has to develop a ray tracing algorithm to handle with the general (including "strong") anisotropic medium and also to design a non-linear inversion solver for later tomography. Meanwhile, it is constructive to investigate how much the tomographic resolution can be improved by introducing the later arrivals. For this motivation, we incorporated our newly developed ray tracing algorithm (multistage irregular shortest-path method) for general anisotropic media with a non-linear inversion solver (a damped minimum norm, constrained least squares problem with a conjugate gradient approach) to formulate a non-linear inversion solver for anisotropic medium. This anisotropic traveltime inversion procedure is able to combine the later (reflected) arrival times. Both 2-D/3-D synthetic inversion experiments and comparison tests show that (1) the proposed anisotropic traveltime inversion scheme is able to recover the high contrast anomalies and (2) it is possible to improve the tomographic resolution by introducing the later (reflected) arrivals, but not as expected in the isotropic medium, because the different velocity (qP, qSV and qSH) sensitivities (or derivatives) respective to the different elastic parameters are not the same but are also dependent on the inclination angle.

  14. T-TY Tank Farm Interim Surface Barrier Demonstration—Vadose Zone Monitoring Plan

    SciTech Connect

    Zhang, Z. F.; Strickland, Christopher E.; Field, Jim G.; Parker, Danny L.

    2010-09-27

    The Hanford Site has 149 underground single-shell tanks that store hazardous radioactive waste. Many of these tanks and their associated infrastructure (e.g., pipelines, diversion boxes) have leaked. Some of the leaked waste has entered the groundwater. The largest known leak occurred from the T-106 Tank of the 241-T Tank Farm in 1973. Five tanks are assumed to have leaked in the TY Farm. Many of the contaminants from those leaks still reside within the vadose zone within the T and TY Tank Farms. The Department of Energy’s Office of River Protection seeks to minimize the movement of these contaminant plumes by placing interim barriers on the ground surface. Such barriers are expected to prevent infiltrating water from reaching the plumes and moving them further. The soil water regime is monitored to determine the effectiveness of the interim surface barriers. Soil-water content and water pressure are monitored using off-the-shelf equipment that can be installed by the hydraulic hammer technique. Four instrument nests were installed in the T Farm in fiscal year (FY) 2006 and FY2007; two nests were installed in the TY Farm in FY2010. Each instrument nest contains a neutron probe access tube, a capacitance probe, and four heat-dissipation units. A meteorological station has been installed at the north side of the fence of the T Farm. This document summarizes the monitoring methods, the instrument calibration and installation, and the vadose zone monitoring plan for interim barriers in T farm and TY Farm.

  15. Deaf People Communicating via SMS, TTY, Relay Service, Fax, and Computers in Australia

    ERIC Educational Resources Information Center

    Power, Mary R.; Power, Des; Horstmanshof, Louise

    2007-01-01

    Despite the expansion of Deaf people's use of communication technology little is published about how they use electronic communication in their social and working lives and the implications for their concepts of identity and community. Australia is an ideal research base because the use of a range of technologies is widespread there. To gain…

  16. A Study on Social Intelligence in Relation to Scholastic Achievement of Student Teachers of B.Ed. and TTI

    ERIC Educational Resources Information Center

    Brindhamani, M.; Manichander, T.

    2014-01-01

    These are difficult times for educators who believe that learning is worth pursuing for its own sake and that the chief purpose of school is the nurturing of students as whole human beings. Higher test scores seem to be the order of the day. The adventure of learning, the wonder of nature and culture, the richness of human experience, and the…

  17. Tissue-type imaging (TTI) based on ultrasonic spectral and clinical parameters for detecting, evaluating, and managing prostate cancer

    NASA Astrophysics Data System (ADS)

    Feleppa, Ernest J.; Ketterling, Jeffrey A.; Dasgupta, Shreedevi; Kalisz, Andrew; Ramachandran, Sarayu; Porter, Christopher R.

    2005-04-01

    This study seeks to develop more-sensitive and -specific ultrasonic methods of imaging cancerous prostate tissue and thereby to improve means of guiding biopsies and planning, targeting, and monitoring treatment. Ultrasonic radio-frequency, echo-signal data, and clinical variables, e.g., PSA, voiding function, etc., during biopsy examinations were acquired. Spectra of the radio-frequency signals were computed in each biopsied region, and used to train neural networks; biopsy results served as the gold standard. A lookup table gave scores for cancer likelihood on a pixel-by-pixel basis from locally computed spectral-parameter and global clinical-parameter values. ROC curves used leave-one-patient- and leave-one-biopsy-out approaches to minimize classification bias. Resulting ROC-curve areas were 0.80+/-0.03 for neural-networks versus 0.66+/-0.03 for conventional classification. TTIs generated from data acquired pre-surgically showed tumors that were unrecognized in conventional images and during surgery. 3-D renderings of prostatectomy histology and TTIs showed encouraging correlations, which shows promise for improving the detection and management of prostate cancer, e.g., for biopsy guidance, planning dose-escalation and tissue-sparing options for radiation or cryotherapy, and assessing the effects of treatment. Combining MRS parameters with US spectral parameters appears capable of further improving prostate-cancer imaging. [Work supported by NIH.

  18. A Critical Examination of the Construct Validity of the TTI Performance DNA[TM] Survey for the Purpose of Differentiating the Entrepreneurially-Minded Engineer

    ERIC Educational Resources Information Center

    Dietrich, Sandra L.

    2012-01-01

    The United States needs workers with more than technical skills to meet the demands of global competition; more specifically, a new breed of engineer is necessary, one who possesses leadership skills and business acumen in addition to the technical engineering skills. One Midwestern foundation has recognized this challenge and is working with…

  19. 47 CFR 6.17 - Informal complaints; form and content.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...., letter, facsimile transmission, telephone (voice/TRS/TTY), Internet e-mail, ASCII text, audio-cassette... transmission, telephone (voice/TRS/TTY), Internet e-mail, ASCII text, audio-cassette recording, braille;...

  20. Dyssynergia Cerebellaris Myoclonica

    MedlinePlus

    ... 301-496-7243; 800-241-1044; 800-241-1055 (TTY) National Organization for Rare Disorders (NORD) 55 ... 301-496-7243; 800-241-1044; 800-241-1055 (TTY) National Organization for Rare Disorders (NORD) 55 ...

  1. Agnosia

    MedlinePlus

    ... 301-496-7243; 800-241-1044; 800-241-1055 (TTY) National Organization for Rare Disorders (NORD) 55 ... 301-496-7243; 800-241-1044; 800-241-1055 (TTY) National Organization for Rare Disorders (NORD) 55 ...

  2. Comparison of the effects of removal of chest hair with not doing so before external defibrillation on transthoracic impedance.

    PubMed

    Sado, Daniel M; Deakin, Charles D; Petley, Graham W; Clewlow, Frank

    2004-01-01

    Chest hair contributes significantly to transthoracic impedance (TTI) during defibrillation. The magnitude of this effect has not been established using external paddles. We compared TTI in 40 men before elective cardiac surgery, and before and after shaving their chests. Chest hair causes a significant increase in TTI during external defibrillation, the magnitude of the effect being related to both the quantity of hair and force applied to the defibrillation paddles. When the chests of nonhirsute patients were shaved, a decrease in TTI occurred, which was probably related to the creation of low-impedance pathways through skin abrasions.

  3. 47 CFR 64.601 - Definitions and provisions of general applicability.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) Text telephone (TTY). A machine that employs graphic communication in the transmission of coded signals... capable of: (i) Receiving and processing subscriber information sufficient to identify unique TRS...

  4. A Trypsin Inhibitor from Tamarind Reduces Food Intake and Improves Inflammatory Status in Rats with Metabolic Syndrome Regardless of Weight Loss

    PubMed Central

    Carvalho, Fabiana M. C.; Lima, Vanessa C. O.; Costa, Izael S.; Medeiros, Amanda F.; Serquiz, Alexandre C.; Lima, Maíra C. J. S.; Serquiz, Raphael P.; Maciel, Bruna L. L.; Uchôa, Adriana F.; Santos, Elizeu A.; Morais, Ana H. A.

    2016-01-01

    Trypsin inhibitors are studied in a variety of models for their anti-obesity and anti-inflammatory bioactive properties. Our group has previously demonstrated the satietogenic effect of tamarind seed trypsin inhibitors (TTI) in eutrophic mouse models and anti-inflammatory effects of other trypsin inhibitors. In this study, we evaluated TTI effect upon satiety, biochemical and inflammatory parameters in an experimental model of metabolic syndrome (MetS). Three groups of n = 5 male Wistar rats with obesity-based MetS received for 10 days one of the following: (1) Cafeteria diet; (2) Cafeteria diet + TTI (25 mg/kg); and (3) Standard diet. TTI reduced food intake in animals with MetS. Nevertheless, weight gain was not different between studied groups. Dyslipidemia parameters were not different with the use of TTI, only the group receiving standard diet showed lower very low density lipoprotein (VLDL) and triglycerides (TG) (Kruskal–Wallis, p < 0.05). Interleukin-6 (IL-6) production did not differ between groups. Interestingly, tumor necrosis factor-alpha (TNF-α) was lower in animals receiving TTI. Our results corroborate the satietogenic effect of TTI in a MetS model. Furthermore, we showed that TTI added to a cafeteria diet may decrease inflammation regardless of weight loss. This puts TTI as a candidate for studies to test its effectiveness as an adjuvant in MetS treatment. PMID:27690087

  5. 75 FR 18228 - Notice of Change in Definitions and Modification to Neighborhood Stabilization Program (NSP)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-09

    ...-708-3587. Persons with hearing or speech impairments may access this number via TTY by calling the... government may give the property owner the perception that condemnation or eminent domain action might be... toll-free number). Hearing or speech-impaired individuals may access this number through TTY by...

  6. 78 FR 64192 - Endangered and Threatened Wildlife and Plants; Extending the Public Comment Periods and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-28

    ... speech-impaired may call the Federal Relay Service at 1- 800-877-8337 for TTY assistance. For information... are hearing- impaired or speech-impaired may call the Federal Relay Service at 1- 800-877-8337 for TTY... final actions resulting from the proposed rules will be based on the best scientific and commercial...

  7. 77 FR 26218 - Federal Housing Administration (FHA): Section 232 Healthcare Facility Insurance Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-03

    ...). Individuals with speech or hearing impairments may access this number via TTY by calling the Federal Relay... not a toll-free number). Persons with hearing or speech impairments may access this number through TTY... commercial property ownership. HUD notes that the single asset entity form of ownership has become...

  8. WWC Review of the Report "Transfer Incentives for High-Performing Teachers: Final Results from a Multisite Randomized Experiment." What Works Clearinghouse Single Study Review

    ERIC Educational Resources Information Center

    What Works Clearinghouse, 2015

    2015-01-01

    For the 2013 study, "Transfer Incentives for High-Performing Teachers: Final Results from a Multisite Randomized Experiment," researchers examined the impact of the Talent Transfer Initiative (TTI) on students' reading and mathematics achievement in 10 school districts. The TTI enabled principals of low-performing schools to provide…

  9. Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes

    SciTech Connect

    Takai, Hiroyuki; Xie, Yihu; de Lange, Titia; Pavletich, Nikola P.

    2010-09-20

    We reported previously that the stability of all mammalian phosphatidylinositol 3-kinase-related protein kinases (PIKKs) depends on their interaction with Tel2, the ortholog of yeast Tel2 and Caenorhabditis elegans Clk-2. Here we provide evidence that Tel2 acts with Hsp90 in the maturation of PIKK complexes. Quantitative immunoblotting showed that the abundance of Tel2 is low compared with the PIKKs, and Tel2 preferentially bound newly synthesized ATM, ATR, mTOR, and DNA-PKcs. Tel2 complexes contained, in addition to Tti1-Tti2, the Hsp90 chaperone, and inhibition of Hsp90 interfered with the interaction of Tel2 with the PIKKs. Analysis of in vivo labeled nascent protein complexes showed that Tel2 and Hsp90 mediate the formation of the mTOR TORC1 and TORC2 complexes and the association of ATR with ATRIP. The structure of yeast Tel2, reported here, shows that Tel2 consists of HEAT-like helical repeats that assemble into two separate {alpha}-solenoids. Through mutagenesis, we identify a surface patch of conserved residues involved in binding to the Tti1-Tti2 complex in vitro. In vivo, mutation of this conserved patch affects cell growth, levels of PIKKs, and ATM/ATR-mediated checkpoint signaling, highlighting the importance of Tti1-Tti2 binding to the function of Tel2. Taken together, our data suggest that the Tel2-Tti1-Tti2 complex is a PIKK-specific cochaperone for Hsp90.

  10. 76 FR 38383 - Revised Public Utility Filing; Requirements for Electric Quarterly Reports; Notice of Electric...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-30

    ... EQR redesign with software implementation now adopting an XML technical approach. A tentative agenda...@ferc.gov or via phone at (866) 208-3676 (toll-free). For TTY, contact (202) 502-8659. For additional... accessibility@ferc.gov or call toll free (866) 208- 3372 (voice) or 202-502-8659 (TTY), or send a fax to...

  11. Spasmodic Dysphonia

    MedlinePlus

    ... MD 20892-3456 Toll-free voice: (800) 241-1044 Toll-free TTY: (800) 241-1055 Email: nidcdinfo@ ... questions in English or Spanish. Voice: (800) 241-1044 TTY: (800) 241-1055 nidcdinfo@nidcd.nih.gov ...

  12. Ear Infections in Children

    MedlinePlus

    ... MD 20892-3456 Toll-free voice: (800) 241-1044 Toll-free TTY: (800) 241-1055 Email: nidcdinfo@ ... questions in English or Spanish. Voice: (800) 241-1044 TTY: (800) 241-1055 nidcdinfo@nidcd.nih.gov ...

  13. Vocal Fold Paralysis

    MedlinePlus

    ... MD 20892-3456 Toll-free voice: (800) 241-1044 Toll-free TTY: (800) 241-1055 Email: nidcdinfo@ ... questions in English or Spanish. Voice: (800) 241-1044 TTY: (800) 241-1055 nidcdinfo@nidcd.nih.gov ...

  14. Recurrent Respiratory Papillomatosis or Laryngeal Papillomatosis

    MedlinePlus

    ... MD 20892-3456 Toll-free voice: (800) 241-1044 Toll-free TTY: (800) 241-1055 Email: nidcdinfo@ ... questions in English or Spanish. Voice: (800) 241-1044 TTY: (800) 241-1055 nidcdinfo@nidcd.nih.gov ...

  15. Auditory Neuropathy

    MedlinePlus

    ... MD 20892-3456 Toll-free voice: (800) 241-1044 Toll-free TTY: (800) 241-1055 Email: nidcdinfo@ ... questions in English or Spanish. Voice: (800) 241-1044 TTY: (800) 241-1055 nidcdinfo@nidcd.nih.gov ...

  16. Apraxia of Speech

    MedlinePlus

    ... MD 20892-3456 Toll-free voice: (800) 241-1044 Toll-free TTY: (800) 241-1055 Email: nidcdinfo@ ... questions in English or Spanish. Voice: (800) 241-1044 TTY: (800) 241-1055 nidcdinfo@nidcd.nih.gov ...

  17. Vestibular Schwannoma (Acoustic Neuroma) and Neurofibromatosis

    MedlinePlus

    ... MD 20892-3456 Toll-free voice: (800) 241-1044 Toll-free TTY: (800) 241-1055 Email: nidcdinfo@ ... questions in English or Spanish. Voice: (800) 241-1044 TTY: (800) 241-1055 nidcdinfo@nidcd.nih.gov ...

  18. Hoarseness

    MedlinePlus

    ... MD 20892-3456 Toll-free voice: (800) 241-1044 Toll-free TTY: (800) 241-1055 Email: nidcdinfo@ ... questions in English or Spanish. Voice: (800) 241-1044 TTY: (800) 241-1055 nidcdinfo@nidcd.nih.gov ...

  19. Ménière's Disease

    MedlinePlus

    ... MD 20892-3456 Toll-free voice: (800) 241-1044 Toll-free TTY: (800) 241-1055 Email: nidcdinfo@ ... questions in English or Spanish. Voice: (800) 241-1044 TTY: (800) 241-1055 nidcdinfo@nidcd.nih.gov ...

  20. Communication Considerations for Parents of Deaf and Hard-of-Hearing Children

    MedlinePlus

    ... MD 20892-3456 Toll-free voice: (800) 241-1044 Toll-free TTY: (800) 241-1055 Email: nidcdinfo@ ... questions in English or Spanish. Voice: (800) 241-1044 TTY: (800) 241-1055 nidcdinfo@nidcd.nih.gov ...

  1. What Is Voice? What Is Speech? What Is Language?

    MedlinePlus

    ... MD 20892-3456 Toll-free voice: (800) 241-1044 Toll-free TTY: (800) 241-1055 Email: nidcdinfo@ ... questions in English or Spanish. Voice: (800) 241-1044 TTY: (800) 241-1055 nidcdinfo@nidcd.nih.gov ...

  2. Taking Care of Your Voice

    MedlinePlus

    ... MD 20892-3456 Toll-free voice: (800) 241-1044 Toll-free TTY: (800) 241-1055 Email: nidcdinfo@ ... questions in English or Spanish. Voice: (800) 241-1044 TTY: (800) 241-1055 nidcdinfo@nidcd.nih.gov ...

  3. Pendred Syndrome

    MedlinePlus

    ... MD 20892-3456 Toll-free voice: (800) 241-1044 Toll-free TTY: (800) 241-1055 Email: nidcdinfo@ ... questions in English or Spanish. Voice: (800) 241-1044 TTY: (800) 241-1055 nidcdinfo@nidcd.nih.gov ...

  4. Noise-Induced Hearing Loss

    MedlinePlus

    ... MD 20892-3456 Toll-free voice: (800) 241-1044 Toll-free TTY: (800) 241-1055 Email: nidcdinfo@ ... questions in English or Spanish. Voice: (800) 241-1044 TTY: (800) 241-1055 nidcdinfo@nidcd.nih.gov ...

  5. Your Baby's Hearing and Communicative Development Checklist

    MedlinePlus

    ... MD 20892-3456 Toll-free voice: (800) 241-1044 Toll-free TTY: (800) 241-1055 Email: nidcdinfo@ ... questions in English or Spanish. Voice: (800) 241-1044 TTY: (800) 241-1055 nidcdinfo@nidcd.nih.gov ...

  6. Sudden Deafness

    MedlinePlus

    ... MD 20892-3456 Toll-free voice: (800) 241-1044 Toll-free TTY: (800) 241-1055 Email: nidcdinfo@ ... questions in English or Spanish. Voice: (800) 241-1044 TTY: (800) 241-1055 nidcdinfo@nidcd.nih.gov ...

  7. Dysphagia

    MedlinePlus

    ... MD 20892-3456 Toll-free voice: (800) 241-1044 Toll-free TTY: (800) 241-1055 Email: nidcdinfo@ ... questions in English or Spanish. Voice: (800) 241-1044 TTY: (800) 241-1055 nidcdinfo@nidcd.nih.gov ...

  8. Otosclerosis

    MedlinePlus

    ... MD 20892-3456 Toll-free voice: (800) 241-1044 Toll-free TTY: (800) 241-1055 Email: nidcdinfo@ ... questions in English or Spanish. Voice: (800) 241-1044 TTY: (800) 241-1055 nidcdinfo@nidcd.nih.gov ...

  9. Balance Disorders

    MedlinePlus

    ... MD 20892-3456 Toll-free voice: (800) 241-1044 Toll-free TTY: (800) 241-1055 Email: nidcdinfo@ ... questions in English or Spanish. Voice: (800) 241-1044 TTY: (800) 241-1055 nidcdinfo@nidcd.nih.gov ...

  10. 47 CFR 64.601 - Definitions and provisions of general applicability.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... CARRIER SERVICES (CONTINUED) MISCELLANEOUS RULES RELATING TO COMMON CARRIERS Telecommunications Relay...)(1)(ii). (1) 711. The abbreviated dialing code for accessing relay services anywhere in the United... use one telephone line for hearing and the other for sending TTY messages. HCO-to-TTY allows a...

  11. 47 CFR 64.601 - Definitions and provisions of general applicability.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... CARRIER SERVICES (CONTINUED) MISCELLANEOUS RULES RELATING TO COMMON CARRIERS Telecommunications Relay...)(1)(ii). (1) 711. The abbreviated dialing code for accessing relay services anywhere in the United...-to-TTY allows a relay conversation to take place between an HCO user and a TTY user....

  12. 75 FR 78682 - Renewal of a Currently Approved Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-16

    ... can be properly assessed. Individuals who use a telecommunications device for the deaf (TTY-TDD) may... telecommunications device for the deaf (TTY-TDD) may call (202) 606-3472 between 8:30 a.m. and 5 p.m. Eastern...

  13. Target-to-target interval, intensity, and P300 from an auditory single-stimulus task.

    PubMed

    Gonsalvez, Craig J; Barry, Robert J; Rushby, Jacqueline A; Polich, John

    2007-03-01

    Target-to-target interval (TTI) is a primary determinant of P300 amplitude, such that longer TTIs yield larger components than shorter intervals. Systematic manipulations of TTI affect component amplitude, latency, and associated response time in a fashion that suggests that the template update hypothesis can account for these outcomes. The present study examines whether manipulations of TTI (from 1 to 16 s) and stimulus intensity (soft and loud tones) produce outcomes consistent with this hypothesis. A single-stimulus task was employed in which only target stimuli were presented. P300 amplitude increased, peak latency decreased, and response time increased as TTI became longer, with less effect for soft compared to loud stimulus conditions on P300 amplitude at Pz. TTI increases also augmented N100 amplitude, with consistently smaller amplitudes obtained for soft relative to loud stimuli. Overall, P300 measures are sensitive to both temporal and physical stimulus factors. Theoretical implications are discussed.

  14. Preliminary Analysis of Images from the Thermospheric Temperature Image on Fast, Affordable, Science and Technology Satellite (FASTSAT)

    NASA Technical Reports Server (NTRS)

    Rodriquez, Marcello; Jones, Sarah; Mentzell, Eric; Gill, Nathaniel

    2011-01-01

    The Thermospheric Temperature Imager (TTI) on Fast, Affordable, Science and Technology SATellite (FASTSAT) measures the upper atmospheric atomic oxygen emission at 135.6 nm and the molecular nitrogen LBH emission at 135.4 nm to determine the atmospheric O/N2 density ratio. Observations of variations in this thermospheric ratio correspond to electron density variations in the ionosphere. The TTI design makes use of a Fabry-Perot interferometer to measure Doppler widened atmospheric emissions to determine neutral atmospheric temperature from low Earth orbit. FASTSAT launched November 10, 2010 and TTI is currently observing geomagnetic signatures in the aurora and airglow. This work is supported by NASA.

  15. 77 FR 32113 - Wireline Competition Bureau Announces Support Amounts for Connect America Fund Phase One...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-31

    ... COMMISSION Wireline Competition Bureau Announces Support Amounts for Connect America Fund Phase One.... SUMMARY: In this document, the Wireline Competition Bureau (Bureau), identifies the data sources it relied... (tty). FOR FURTHER INFORMATION CONTACT: Joseph Cavender, Wireline Competition Bureau at (202)...

  16. 78 FR 48199 - Comment Request for Information Collection for Employers Survey of the Short-Time Compensation...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-07

    ... program. The objective of the study is to understand employers' awareness and perceptions of the STC...). Individuals with hearing or speech impairments may access the telephone number above via TTY by calling...

  17. 77 FR 38050 - Pepco Holdings, Inc.; Notice of Petition for Limited Waiver

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-26

    ... cost'' pricing for a limited set of transitions, as more fully described in the filing. Any person...@ferc.gov . or call (866) 208-3676 (toll free). For TTY, call (202) 502-8659. Comment Date: 5...

  18. 76 FR 42470 - Loan Policies and Operations; Loan Purchases From FDIC; Effective Date

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-19

    ... Policy Analyst, Office of Regulatory Policy, Farm Credit Administration, McLean, Virginia 22102-5090..., Farm Credit Administration, McLean, Virginia 22102-5090, (703) 883-4020, TTY (703) 883-4020. (12...

  19. 77 FR 76356 - Disclosure to Investors in System-wide and Consolidated Bank Debt Obligations of the Farm Credit...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-28

    ... Administration, McLean, Virginia 22102-5090, (703) 883-4498, TTY (703) 883-4434, or Laura McFarland, Senior Counsel, Office of General Counsel, Farm Credit Administration, McLean, Virginia 22102-5090, (703)...

  20. 76 FR 20297 - Implementing the Provisions of the Communications Act of 1934, as Enacted by the Twenty-First...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-12

    ..., ] Accessible Mobile Phone Options for People who are Blind, Deaf-Blind, or Have Low Vision, CG Docket No. 10... phone: (202) 418-0530 or TTY: (202) 418-0432. FOR FURTHER INFORMATION CONTACT: Jeffrey Tignor,...

  1. 78 FR 40312 - 30-Day Notice of Proposed Information Collection: FHA TOTAL (Technology Open to Approved Lenders...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-03

    ... with hearing or speech impairments may access this number through TTY by calling the toll-free Federal... Association (MBA). MISMO's mission is to develop leading technical standards for residential and...

  2. 78 FR 8552 - Announcement of Funding Awards, HOPE VI Main Street Grant Program, Fiscal Year (FY) 2011 and 2012

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-06

    ... or speech-impaired individuals may access this number via TTY by calling the toll-free Federal... traditional central business district or ``Main Street'' area by replacing unused commercial space...

  3. 76 FR 59151 - Announcement of Funding Awards; HOPE VI Main Street Grant Program, Fiscal Year (FY) 2009

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-23

    ... toll-free number.) Persons with hearing or speech impairments may access this number through TTY by...'' area by replacing unused commercial space in buildings with affordable housing units. The objectives...

  4. 76 FR 38408 - Notice of Funding Availability (NOFA) for HUD's Fiscal Year 2011 HOPE VI Main Street Grants

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-30

    ... district or ``Main Street'' area by replacing unused commercial space in buildings with affordable housing... hearing or speech impairments may access these numbers via TTY by calling the Federal Information...

  5. Your Discharge Planning Checklist

    MedlinePlus

    ... Visit benefitscheckup. org . State Health Insurance Assistance Programs (SHIPs): Offer counseling on health insurance and programs for ... MEDICARE (1-800-633-4227) to get your SHIP’s phone number. TTY users should call 1-877- ...

  6. 76 FR 38547 - Technical Updating Amendments to Executive Branch Financial Disclosure and Standards of Ethical...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-01

    ... Newton, Attorney-Advisor, Office of Government Ethics; Telephone: 202-482-9300; TTY: 800-877- 8339; FAX... law at the same time this rulemaking document is sent to the Office of the Federal Register...

  7. 76 FR 73619 - Francis Walter Hydro, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-29

    ... Corps of Engineers (Corps) Francis E. Walter Dam located on the Lehigh River, in Luzerne County... TTY, (202) 502-8659. Although the Commission strongly encourages electronic filing, documents may...

  8. 77 FR 7597 - Waiver of Debt

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-13

    ... speech disability or hearing loss and use a TTY, call 1-800-462-7585 directly; if you use 711 or Video... individuals an opportunity to appeal a FEMA debt determination and, in some cases, to request an oral...

  9. 36 CFR 1193.51 - Compatibility.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... a connector by the user. (b) Connection point for external audio processing devices. Products providing auditory output shall provide the auditory signal at a standard signal level through an industry...) TTY signal compatibility. Products, including those providing voice communication functionality,...

  10. 36 CFR 1193.51 - Compatibility.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... a connector by the user. (b) Connection point for external audio processing devices. Products providing auditory output shall provide the auditory signal at a standard signal level through an industry...) TTY signal compatibility. Products, including those providing voice communication functionality,...

  11. 36 CFR 1193.51 - Compatibility.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... a connector by the user. (b) Connection point for external audio processing devices. Products providing auditory output shall provide the auditory signal at a standard signal level through an industry...) TTY signal compatibility. Products, including those providing voice communication functionality,...

  12. 36 CFR 1193.51 - Compatibility.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... a connector by the user. (b) Connection point for external audio processing devices. Products providing auditory output shall provide the auditory signal at a standard signal level through an industry...) TTY signal compatibility. Products, including those providing voice communication functionality,...

  13. 47 CFR 7.17 - Informal complaints; form and content.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ..., telephone (voice/TRS/TTY), Internet e-mail, ASCII text, Internet e-mail, audio-cassette recording, and...), Internet e-mail, ASCII text, audio-cassette recording, braille; or some other method that will...

  14. 47 CFR 7.17 - Informal complaints; form and content.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ..., telephone (voice/TRS/TTY), Internet e-mail, ASCII text, Internet e-mail, audio-cassette recording, and...), Internet e-mail, ASCII text, audio-cassette recording, braille; or some other method that will...

  15. 47 CFR 68.417 - Informal complaints; form and content.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... reasonable means, e.g., letter, facsimile transmission, telephone (voice/TRS/TTY), Internet e-mail, ASCII...), Internet e-mail, ASCII text, audio-cassette recording, Braille; or some other method that will...

  16. 14 CFR Appendix B to Part 382 - Cross-Reference Table

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... assistive devices, POCs and other respiratory assistive devices. 43(a) 129(b) Timely return of assistive...) 45 Availability of copy of rule. 47(a) 43 TTY's and reservations systems. 47(b) 69 Accessibility...

  17. 76 FR 14039 - Collection of Overpayments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-15

    ... includes a section describing ``Your Rights and Options'' and provides general information to the public on..., hard of hearing or those with speech disabilities may access this number through TTY by calling...

  18. 75 FR 37842 - Privacy Act of 1974; Systems of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-30

    ...-4040 during normal business hours. (TTY and TDD users may call the Federal relay service toll-free at 1... of an issue necessary to resolve an appeal. 6. The name and social security number of a...

  19. 75 FR 5621 - Notice of Proposed Information Collection for Public Comment; Multifamily Tenant Characteristics...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-03

    ...) 877-8339. (Other than the HUD USER information line and TTY numbers, telephone numbers are not toll... profile, income and housing information on the entire nationwide population of tenants residing...

  20. 75 FR 65359 - Common Formats for Patient Safety Data Collection and Event Reporting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-22

    ...; Telephone (toll free): (866) 403-3697; Telephone (local): (301) 427-1111; TTY (toll free): (866) 438-7231... 1.1 includes updated event descriptions, forms, and technical specifications for software...

  1. Development of Aa New Time Temperature Indicator for Enzymatic Validation of Pasteurization of Meat Products.

    PubMed

    Brizio, Ana Paula Dutra Resem; Prentice, Carlos

    2015-06-01

    This paper presents the development of a new smart time-temperature indicator (TTI) of pasteurization whose operating principle is based on the complexation reaction between starch and iodine, and the subsequent action of an amylase on this complex causing its discoloration at a rate dependent on time and temperature of the medium. Laboratory simulations and tests in a manufacturing plant evaluated different enzyme concentrations in the TTI prototypes when exposed to pasteurization conditions. The results showed that the color response of the indicators was visually interpreted as adaptive to measurement using appropriate equipment, with satisfactory reliability in all conditions studied. The TTI containing 6.5% amylase was one whose best results were suited for use in validating the cooking of hams. When attached to the primary packaging of the product, this TTI indicated the pasteurization process inexpensively, easily, accurately, and nondestructively.

  2. 78 FR 66913 - Notice of Application for Amendment of License and Soliciting Comments, Motions To Intervene, and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-07

    ... reproduction at the Commission's Public Reference Room, located at 888 First Street NE., Room 2A, Washington... , for TTY, call (202) 502-8659. A copy is also available for inspection and reproduction at the...

  3. Finite Difference Modeling of Wave Progpagation in Acoustic TiltedTI Media

    SciTech Connect

    Zhang, Linbin; Rector III, James W.; Hoversten, G. Michael

    2005-03-21

    Based on an acoustic assumption (shear wave velocity is zero) and a dispersion relation, we derive an acoustic wave equation for P-waves in tilted transversely isotropic (TTI) media (transversely isotropic media with a tilted symmetry axis). This equation has fewer parameters than an elastic wave equation in TTI media and yields an accurate description of P-wave traveltimes and spreading-related attenuation. Our TTI acoustic wave equation is a fourth-order equation in time and space. We demonstrate that the acoustic approximation allows the presence of shear waves in the solution. The substantial differences in traveltime and amplitude between data created using VTI and TTI assumptions is illustrated in examples.

  4. 77 FR 73632 - American Municipal Power, Inc; Notice of Application for Temporary Variance of License and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-11

    ... the Application: A copy of the application is available for inspection and reproduction at the [[Page... , for TTY, call (202) 502-8659. A copy is also available for inspection and reproduction at the...

  5. 77 FR 42715 - North American Hydro Holdings, LLC; Notice of Application Accepted for Filing, Soliciting Motions...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-20

    ... reproduction at the Commission's Public Reference Room, located at 888 First Street NE., Room 2A, Washington... , for TTY, call (202) 502-8659. A copy is also available for inspection and reproduction at the...

  6. 76 FR 41236 - FPL Energy Maine Hydro, LLC; Notice of Application Accepted for Filing and Soliciting Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-13

    ... reproduction at the Commission's Public Reference Room, located at 888 First Street, NE., Room 2A, Washington...@ferc.gov , for TTY, call (202) 502-8659. A copy is also available for inspection and reproduction...

  7. 78 FR 44627 - HOME Investment Partnerships Program: Improving Performance and Accountability; Updating Property...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-24

    ... 7164, Washington, DC 20410; telephone number 202-708- 2684 (this is not a toll-free number). Persons with hearing or speech impairments may access this number through TTY by calling the toll-free...

  8. High-flow transtracheal insufflation treats obstructive sleep apnea. A pilot study.

    PubMed

    Schneider, H; O'Hearn, D J; Leblanc, K; Smith, P L; O'Donnell, C P; Eisele, D W; Peter, J H; Schwartz, A R

    2000-06-01

    To determine the effect of transtracheal insufflation (TTI) on obstructive sleep apnea (OSA), we examined breathing patterns in five tracheostomized patients with OSA at varying TTI flow rates when breathing with a closed tracheostomy. The breathing patterns and polysomnographic responses to air insufflation were studied as TTI was increased from 0 to 15 L/min for brief periods of non-rapid eye movement (NREM) sleep (Experiment 1). The frequency of sleep-disordered breathing episodes remained high at 0 and 5 L/min (87.0 +/- 33.7 and 79.4 +/- 24.4 episodes per hour NREM) and decreased significantly to 41.3 +/- 31.5 and 43.4 +/- 31.4 episodes/h NREM sleep at rates of 10 and 15 L/min, respectively (p = 0.003). At high levels of TTI (10 and 15 L/min), obstructive apneas and hypopneas decreased but periodic laryngeal obstructions were induced during stage 1 NREM sleep. To prevent laryngeal obstructions, a servo-control system was used to briefly interrupt TTI during these events. When this system was implemented for more prolonged periods of sleep (Experiment 2, total sleep time 176.6 +/- 12.5 min), high-flow TTI (hf-TTI, 15 L/min) led to an overall reduction in the combined frequency of obstructive apneas and laryngeal obstructions from 63.8 +/- 21.8 to 10.7 +/- 9.1 (p < 0.03) and was associated with a marked reduction in arousal frequency from 60.0 +/- 26.0 to 8. 3 +/- 5.4/h in NREM sleep, and from 67.5 +/- 3.5 to 0 +/- 0/h in rapid eye movement (REM) sleep. Our findings demonstrate that hf-TTI stabilized breathing patterns in apneic patients, and was safe and efficacious for prolonged periods of sleep.

  9. Extended study on the influence of z-value(s) of single and multicomponent time-temperature integrators on the accuracy of quantitative thermal process assessment.

    PubMed

    Guiavarc'h, Yann P; van Loey, Ann M; Hendrickx, Marc E

    2005-02-01

    The possibilities and limitations of single- and multicomponent time-temperature integrators (TTIs) for evaluating the impact of thermal processes on a target food attribute with a Ztarget value different from the zTTI value(s) of the TTI is far from sufficiently documented. In this study, several thousand time-temperature profiles were generated by heat transfer simulations based on a wide range of product and process thermal parameters and considering a Ztarget value of 10 degrees C and a reference temperature of 121.1 degrees C, both currently used to assess the safety of food sterilization processes. These simulations included 15 different Ztarget=10 degrees CF121.1 degrees C values in the range 3 to 60 min. The integration of the time-temperature profiles with ZTTI values of 5.5 to 20.5 degrees C in steps of 1 degrees C allowed generation of a large database containing for each combination of product and process parameters the correction factor to apply to the process value FmultiTTI, which was derived from a single- or multicomponent TTI, to obtain the target process value 10 degrees CF121.1 degrees C. The table and the graph results clearly demonstrated that multicomponent TTIs with z-values close to 10 degrees C can be used as an extremely efficient approach when a single-component TTI with a z-value of 10 degrees C is not available. In particular, a two-component TTI with z1 and z2 values respectively above and below the Ztarget value (10 degrees C in this study) would be the best option for the development of a TTI to assess the safety of sterilized foods. Whatever process and product parameters are used, such a TTI allows proper evaluation of the process value 10 degrees CF121.1 degrees C.

  10. Effect of skin sympathetic response to local or systemic cold exposure on thermoregulatory functions in humans.

    PubMed

    Sawasaki, N; Iwase, S; Mano, T

    2001-03-23

    We studied how, sympathetic response to cold exposure determines thermoregulatory function. Three female and seven male volunteers (age, 23.2+/-1.9 years) were exposed to abrupt local cooling and gradual systemic cooling with recording of microneurographic skin sympathetic nerve activity tSSNA), skill temperatures (Ts), tympanic temperature (Tty), skin blood flow measured by laser Doppler flowmetry, and sweating rate measured with a ventilated capsule. Local cooling induced an abrupt vasoconstrictor SSNA increase and Tty rise. There was a significant positive correlation between the increase in the vasoconstrictor SSNA and the change rate of Tty. Systemic cooling at 0.2 degrees C/min enhanced SSNA but gradually decreased Tty, and a significant negative correlation was observed between them. A 10-min delay separated the SSNA rise from the subsequent Tty rise following local cooling. A delay of less than 1 min preceded the SSNA increase after the Tty fall induced by systemic cooling. These findings suggested that subjects with a good SSNA response to cold stress can maintain core temperature, but 10 min is necessary to raise the core temperature by reducing heat loss from the skin surface. In contrast. vasoconstrictor SSNA responds linearly to a fall in core temperature with a delay of less than 1 min.

  11. Validity of infrared tympanic temperature for the evaluation of heat strain while wearing impermeable protective clothing in hot environments.

    PubMed

    Lee, Joo-Young; Nakao, Kouhei; Takahashi, Naoki; Son, Su-Young; Bakri, Ilham; Tochihara, Yutaka

    2011-01-01

    The purpose of this study was to investigate the validity of infrared tympanic temperature (IR T(ty)) as a thermal index to evaluate the heat strain of workers in hot environments, in comparison with rectal temperatures at various depths (T(re-4, -8, and -16) for 4, 8 and 16 cm from the anal sphincter). Eight males underwent twelve experimental conditions: two activities (rest and exercise) × three clothing levels [Control, HDPE (high-density polyethylene coverall) and PVC (polyvinyl chloride coverall) condition] × two air temperatures (25 and 32℃ with 50%RH). The results showed that 1) in the conditions with most heat strain (HDPE or PVC condition at 32℃), IR T(ty) was equal to or even higher than T(re); 2) during exercise, physiological strain index (PSI) using IR T(ty) did not underestimate PSI-values using T(re-16), and overestimated those PSI-values from T(re-16) in HDPE and PVC conditions at 32℃; 3) during exercise, the relationships between IR T(ty) and heart and total sweat rate were stronger than those between T(re-16) and heart and total sweat rate. These results indicated that IR T(ty) is valid as a thermal index to evaluate the heat strain of workers wearing impermeable protective coveralls in hot environments. However, the application of IR T(ty) is limited only for strenuous works wearing encapsulated personal protective clothing with a hood in heat.

  12. Microsurgical anatomy of the transsylvian translimen insula approach to the mediobasal temporal lobe: Technical considerations and case illustration

    PubMed Central

    Straus, David; Byrne, Richard W.; Sani, Sepehr; Serici, Anthony; Moftakhar, Roham

    2013-01-01

    Background: Various vascular, neoplastic, and epileptogenic pathologies occur in the mediobasal temporal region. A transsylvian translimen insula (TTI) approach can be used as an alternative to temporal transcortical approach to the mediobasal temporal region. The aim of this study was to demonstrate the surgical anatomy of the TTI approach, including the gyral, sulcal, and vascular anatomy in and around the limen insula. The use of this approach is illustrated in the resection of a complex arteriovenous malformation. Methods: The TTI approach to the mediobasal temporal region was performed on three silicone-injected cadaveric heads. The gyral, sulcal, and arterial anatomy of the limen insula was studied in six formalin-fixed injected hemispheres. Results: The TTI approach provided access to the anterior and middle segments of the mediobasal temporal lobe region as well as allowing access to temporal horn of the lateral ventricle. Using this approach we were able to successfully resect an arteriovenous malformation of the dominant medial temporal lobe. Conclusion: The TTI approach provides a viable surgical route to the region of mediobasal temporal lobe region. This approach offers an advantage over the temporal transcortical route in that there is less risk of damage to optic radiations and speech area in the dominant hemisphere. PMID:24404402

  13. In vivo bioinsecticidal activity toward Ceratitis capitata (fruit fly) and Callosobruchus maculatus (cowpea weevil) and in vitro bioinsecticidal activity toward different orders of insect pests of a trypsin inhibitor purified from tamarind tree (Tamarindus indica) seeds.

    PubMed

    Araújo, Carina L; Bezerra, Ingrid W L; Oliveira, Adeliana S; Moura, Fabiano T; Macedo, Leonardo L P; Gomes, Carlos E M; Barbosa, Aulus E A D; Macedo, Francisco P; Souza, Tánia M S; Franco, Octavio L; Bloch-J, Carlos; Sales, Mauricio P

    2005-06-01

    A proteinaceous inhibitor with high activity against trypsin-like serine proteinases was purified from seeds of the tamarind tree (Tamarindus indica) by gel filtration on Shephacryl S-200 followed by a reverse-phase HPLC Vidac C18 TP. The inhibitor, called the tamarind trypsin inhibitor (TTI), showed a Mr of 21.42 kDa by mass spectrometry analysis. TTI was a noncompetitive inhibitor with a Ki value of 1.7 x 10(-9) M. In vitro bioinsecticidal activity against insect digestive enzymes from different orders showed that TTI had remarkable activity against enzymes from coleopteran, Anthonomus grandis (29.6%), Zabrotes subfasciatus (51.6%), Callosobruchus maculatus (86.7%), Rhyzopertha dominica(88.2%), and lepidopteron, Plodia interpuncptella (26.7%), Alabama argillacea (53.8%), and Spodoptera frugiperda (75.5%). Also, digestive enzymes from Diptera, Ceratitis capitata (fruit fly), were inhibited (52.9%). In vivo bioinsecticidal assays toward C. capitata and C. maculatus larvae were developed. The concentration of TTI (w/w) in the artificial seed necessary to cause 50% mortality (LD50) of larvae was 3.6%, and that to reduce mass larvae by 50.0% (ED50) was 3.2%. Furthermore, the mass C. capitata larvae were affected at 53.2% and produced approximately 34% mortality at a level of 4.0% (w/w) of TTI incorporated in artificial diets.

  14. Notification of transfusion transmitted infection.

    PubMed

    Choudhury, Lincoln P; Tetali, Shailaja

    2008-01-01

    The National Blood Policy of India, 2002, advocates the disclosure of results of transfusion transmitted infections (TTI) to blood donors. However, in the absence of well-defined notification processes, and in order to avoid serious consequences resulting from unguided disclosure, blood bank personnel discard blood that is TTI-positive. We report on a survey of 105 voluntary blood donors in Kerala. Only two out of three participants had filled the donor form in the last year. Only half were aware that the blood bank was supposed to inform them if they tested positive for TTI. Fifty-seven per cent of donors wanted to be informed every time they donated blood, irrespective of a positive or negative result.

  15. Integrated Science: Florida Manatees and Everglades Hydrology

    USGS Publications Warehouse

    Langtimm, Catherine A.; Swain, Eric D.; Stith, Bradley M.; Reid, James P.; Slone, Daniel H.; Decker, Jeremy; Butler, Susan M.; Doyle, Terry; Snow, R.W.

    2009-01-01

    Predicting and monitoring restoration effects on Florida manatees, which are known to make extended movements, will be incomplete if modeling and monitoring are limited to the smaller areas defined by the various res-toration components. U.S. Geological Survey (USGS) efforts, thus far, have focused on (1) collecting manatee movement data throughout the Ten Thousand Islands (TTI) region, and (2) developing an individual-based model for manatees to illustrate manatee responses to changes in hydrology related to the Picayune Strand Restoration Project (PSRP). In 2006, new regional research was begun to extend an Everglades hydrology model into the TTI region; extend the manatee movement model into the southern estuaries of Everglades National Park (ENP); and integrate hydrology and manatee data, models, and monitoring across the TTI region and ENP. Currently (2008), three research tasks are underway to develop the necessary modeling components to assess restoration efforts across the Greater Everglades Ecosystem.

  16. Time--temperature indicator for perishable products based on kinetically programmable Ag overgrowth on Au nanorods.

    PubMed

    Zhang, Chao; Yin, An-Xiang; Jiang, Ruibin; Rong, Jie; Dong, Lu; Zhao, Tian; Sun, Ling-Dong; Wang, Jianfang; Chen, Xing; Yan, Chun-Hua

    2013-05-28

    Food safety is a constant concern for humans. Besides adulteration and contamination, another major threat comes from the spontaneous spoilage of perishable products, which is basically inevitable and highly dependent on the temperature history during the custody chain. For advanced quality control and assessment, time-temperature indicators (TTIs) can be deployed to document the temperature history. However, the use of TTIs is currently limited by either relatively high cost or poor programmability. Here we describe a general, kinetically programmable, and cost-efficient TTI protocol constructed from plasmonic nanocrystals. We present proof-of-principle demonstrations that our TTI can be specifically tailored and thus used to track perishables, dynamically mimic the deteriorative processes therein, and indicate product quality through sharp-contrast multicolor changes. The flexible programmability of our TTI, combined with its substantially low cost and low toxicity, promises a general applicability to each single packaged item of a plethora of perishable products.

  17. Ignition of Composite Propellants under Rapid Pressure Loading

    DTIC Science & Technology

    1981-09-01

    known surface temperature-time history2 2 is q"t)= kpc t~), T(t) - T(T) (2(t .4 Lt T / d-r 5 ) where T(t) is the measured surface temperature. The...approximated by a piecewise linear function. The final expression for heat flux is given by kpc T n-l (t - T(t.) T(tn) - T(ti. ) T(ti) - T(ti-) 1 T2tn - T...As *.h- T,rý•l-•int 11ýnc- t!;, incorporating a solid propellant charge crack bec-in; t...’- , l.ca1 rr-.s.ur, was used as the source of hot gas gene

  18. Orbit Determination Error Analysis Results for the Triana Sun-Earth L2 Libration Point Mission

    NASA Technical Reports Server (NTRS)

    Marr, G.

    2003-01-01

    Using the NASA Goddard Space Flight Center's Orbit Determination Error Analysis System (ODEAS), orbit determination error analysis results are presented for all phases of the Triana Sun-Earth L1 libration point mission and for the science data collection phase of a future Sun-Earth L2 libration point mission. The Triana spacecraft was nominally to be released by the Space Shuttle in a low Earth orbit, and this analysis focuses on that scenario. From the release orbit a transfer trajectory insertion (TTI) maneuver performed using a solid stage would increase the velocity be approximately 3.1 km/sec sending Triana on a direct trajectory to its mission orbit. The Triana mission orbit is a Sun-Earth L1 Lissajous orbit with a Sun-Earth-vehicle (SEV) angle between 4.0 and 15.0 degrees, which would be achieved after a Lissajous orbit insertion (LOI) maneuver at approximately launch plus 6 months. Because Triana was to be launched by the Space Shuttle, TTI could potentially occur over a 16 orbit range from low Earth orbit. This analysis was performed assuming TTI was performed from a low Earth orbit with an inclination of 28.5 degrees and assuming support from a combination of three Deep Space Network (DSN) stations, Goldstone, Canberra, and Madrid and four commercial Universal Space Network (USN) stations, Alaska, Hawaii, Perth, and Santiago. These ground stations would provide coherent two-way range and range rate tracking data usable for orbit determination. Larger range and range rate errors were assumed for the USN stations. Nominally, DSN support would end at TTI+144 hours assuming there were no USN problems. Post-TTI coverage for a range of TTI longitudes for a given nominal trajectory case were analyzed. The orbit determination error analysis after the first correction maneuver would be generally applicable to any libration point mission utilizing a direct trajectory.

  19. Advances in vaccine stability monitoring technology.

    PubMed

    Zweig, Stephen E

    2006-08-14

    Electronic time-temperature indicator (eTTI) monitors can be programmed to exactly follow the stability characteristics of vaccines with a high degree of realism. The monitors have a visual output, enabling vaccine status to be assessed at a glance, and can also output more detailed statistical data. When packaged with vaccine vials in groups of about 10 vials per box, the eTTI can remain with a vaccine throughout most of the vaccine's lifetime. The monitors can detect essentially all cold-chain breaks, and can detect issues, such as inadvertent freezing, that are presently not detected by other vaccine stability monitors such as Vaccine Vial Monitors (VVM).

  20. A shared regulatory perspective on deferral from blood donation of men who have sex with men (MSM).

    PubMed

    Epstein, J; Ganz, P R; Seitz, R; Jutzi, M; Schaerer, C; Michaud, G; Agbanyo, F; Smith, G; Prosser, I; Heiden, M; Saint-Marie, I; Oualikene-Gonin, W; Hamaguchi, I; Yasuda, N

    2014-11-01

    National Regulatory Authorities (NRAs) establish deferral criteria for donors with risk factors for transfusion transmissible infections (TTI). In most jurisdictions, epidemiological data show that men who have sex with men (MSM) have a significantly higher rate of TTI than the general population. Nevertheless, changes from an indefinite donor deferral for MSM have been considered in many countries in response to concerns over a perceived discrimination and questioning of the scientific need. Changes to MSM donor deferral criteria should be based on sound scientific evidence. Safety of transfusion recipients should be the first priority, and stakeholder input should be sought.

  1. Elevations and distances in the United States

    USGS Publications Warehouse

    ,

    2001-01-01

    Further information about U.S. Geological Survey products can be obtained from: U.S. Geological Survey, Earth Science Information Center, 507 National Center, Reston, VA 20192 or phone 1-888-ASK-USGS, E-mail: ask@usgs.gov, TTY: 703-648-4119.

  2. The text telephone as an empowering technology in the daily lives of deaf people-A qualitative study.

    PubMed

    Roos, Carin; Wengelin, Åsa

    2016-01-01

    Text-telephone technology (TTY) has been used for communication between deaf people since 1964. There is a gap in the scientific knowledge about the influence this may have had especially in relation to effective participation in society as well as the feeling of capability, confidence and collective meaningfulness. The aim of the present paper is, first, to disentangle the different aspects of TTY as an empowering artifact; and, second, to explore the role of TTY in their lives. To provide a framework for the empirical analysis, the paper draws on Empowerment Theory: personal control, a proactive approach to life, and a critical awareness of one's socio-political environment. Twenty-four people aged 16-64 with Swedish Sign Language (SSL) as their first language were interviewed. The findings indicate that the introduction of the TTY was of great importance for self-esteem, equality and independence. The findings show that feelings of empowerment are closely linked to language use and contextually driven, and it is in interaction between deaf and hearing that such feelings arise (or not). The results indicate the need for further research into Deaf people's use of other means of interacting, using modern technique for example in social digital media and interactive platforms.

  3. 76 FR 24489 - Privacy Act of 1974; Amendment to System of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-02

    ... Routine Use Comment'' in the subject line of the message). Fax: 202-482-9237, Attention: Elaine Newton..., NW., Washington, DC 20005-3917, Attention: Elaine Newton, Privacy Officer. FOR FURTHER INFORMATION CONTACT: Ms. Newton at the Office of Government Ethics; telephone: 202-482-9265; TTY: 800-877-8339;...

  4. 78 FR 56188 - Wireline Competition Bureau Announces Availability of Version 3.2 of the Connect America Fund...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-12

    ... COMMISSION 47 CFR Part 54 Wireline Competition Bureau Announces Availability of Version 3.2 of the Connect...: Proposed rule. SUMMARY: In this document, the Wireline Competition Bureau announces the availability of the... INFORMATION CONTACT: Katie King, Wireline Competition Bureau at (202) 418-7491 or TTY (202)...

  5. 78 FR 35632 - Wireline Competition Bureau Provides Guidance Regarding the 2013 Lifeline Recertification Process

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-13

    ... COMMISSION Wireline Competition Bureau Provides Guidance Regarding the 2013 Lifeline Recertification Process... Competition Bureau (Bureau) provides guidance regarding the 2013 Lifeline recertification process. The Bureau..., Wireline Competition Bureau, (202) 418-7387 or TTY: (202) 418-0484. SUPPLEMENTARY INFORMATION: This is...

  6. 77 FR 24690 - Exemplary Charter School Collaboration Awards; Proposed Definitions, Requirements, and Selection...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-25

    ... device for the deaf (TDD) or a text telephone (TTY), call the Federal Relay Service, toll free, at 1-800... An applicant for a Collaboration Award must-- (1) Provide a detailed narrative describing (a) the... the competition; and Agree to have the executive summary or narrative of the application,...

  7. 77 FR 49005 - Notice of Proposed Information Collection for Public Comment; Indian Housing Block Grant (IHBG...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-15

    ...., Room 4160, Washington, DC 20410-5000; telephone 202-402-3400, (this is not a toll-free number) or email... information. Persons with hearing or speech impairments may access this number through TTY by calling the toll-free Federal Information Relay Service at (800) 877-8339. (Other than the HUD USER information line...

  8. 75 FR 69454 - Emergency Homeowners' Loan Program: Notice of Allocation of Funding for Substantially Similar...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-12

    ... a toll-free number). Persons with hearing or speech impairments may access this number through TTY by calling the toll-free Federal Information Relay Service at 800-877-8339. Overview Information: A... meet their mortgage obligations. \\1\\ To the extent that a state does not submit information about...

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  10. 75 FR 69363 - HUD Multifamily Rental Projects: Regulatory Revisions

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    2010-11-12

    ...-3055 (this is not a toll-free number). Individuals with speech or hearing impairments may access this...-708-1274 (this is not a toll-free number). Persons with hearing or speech impairments may access this number through TTY by calling the toll-free Federal Information Relay Service at 800-877-...

  11. 77 FR 71099 - Federal Housing Administration (FHA): Temporary Waiver of FHA's Regulation on Property Flipping...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-29

    ...-8000; telephone number 202-708-2121 (this is not a toll-free number). Persons with hearing or speech impairments may access this number through TTY by calling the toll-free Federal Relay Service at 800-877-8339.... Additionally, the waiver is subject to certain conditions, and mortgages must meet these conditions to...

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    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-24

    ... 4160, Washington, DC 20410-5000; telephone 202.402.3400 (this is not a toll-free number) or e-mail Ms. Pollard at Colette_Pollard@hud.gov . Persons with hearing or speech impairments may access this number through TTY by calling the toll-free Federal Information Relay Service at (800) 877-8339. (Other than...

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    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-15

    ... 202-402-3400 (this is not a toll- free number) or email Ms. Pollard at Colette_Pollard@hud.gov . Persons with hearing or speech impairments may access this number through TTY by calling the toll-free... is not a toll-free number). Persons with hearing or speech impairments may access this number via...

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    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-03

    ... at Colette.Pollard@hud.gov or telephone 202-402-3400. Persons with hearing or speech impairments may access this number through TTY by calling the toll-free Federal Relay Service at (800) 877-8339. This is not a toll- free number. Copies of available documents submitted to OMB may be obtained from...

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    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-05

    ... toll-free number) or email Ms. Pollard at Colette_Pollard@hud.gov . Persons with hearing or speech impairments may access this number through TTY by calling the toll-free Federal Information Relay Service at... toll-free.) FOR FURTHER INFORMATION CONTACT: Arlette Mussington, Office of Policy, Programs...

  16. 76 FR 16531 - Technical Correction for Neurological Listing Cross-Reference

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-24

    ... toll-free number, 1-800-772-1213, or TTY 1-800-325-0778, or visit our Internet site, Social Security... rules that revised the portions of section 102.00 (the Special Senses and Speech body system for... (OMB) and determined that this final rule does not meet the requirements for a significant...

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    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-14

    ... Street, SW., Room 6138, Washington, DC 20410, telephone number (202) 402-6732. (These are not toll free telephone numbers). A telecommunications device for hearing- and speech-impaired individuals (TTY) is..., reduce and correct fraud and abuse in rental housing assistance programs. In meeting this objective,...

  18. 76 FR 27341 - Notice of Proposed Information Collection for Public Comment; Indian Housing Block Grant (IHBG...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-11

    ...-3400, (this is not a toll-free number) or e-mail Ms. Pollard at Colette.Pollard@hud.gov for a copy of the proposed forms, or other available information. Persons with hearing or speech impairments may access this number through TTY by calling the toll-free Federal Information Relay Service at (800)...

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    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-13

    ...., Room 4160, Washington, DC 20410-5000; telephone 202-402-3400, (this is not a toll-free number) or e-mail Ms. Pollard at Collette.Pollard@hud.gov . Persons with hearing or speech impairments may access this number through TTY by calling the toll-free Federal Information Relay Service at...

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  1. 78 FR 40161 - Announcement of Issuance by HUD of Notice of Senior Preservation Rental Assistance Contracts...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-03

    ... toll-free number). Persons with hearing or speech impairments may access this number through TTY by calling the toll-free Federal Relay Service at 800-877-8339. SUPPLEMENTARY INFORMATION: The Section 202... SPRACs with 20-year terms to Owner-Applicants and existing Section 202 properties that meet the...

  2. 76 FR 53362 - Approval of Farm Credit System Lending Institutions in FHA Mortgage Insurance Programs

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-26

    ... Regulations ] Division at 202-708-3055 (this is not a toll-free number). Individuals with speech or hearing... 202-708- 1515 (this is not a toll-free number). Persons with hearing or speech impairments may access this number through TTY by calling the toll-free Federal Information Relay Service at...

  3. 76 FR 62434 - HUD Draft Environmental Justice Strategy

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-07

    ..., Washington, DC 20410; telephone number 202- 402-6731 (this is not a toll-free number). Persons with hearing or speech impairments may access this number through TTY by calling the toll-free Federal Relay Service at 800-877-8339. SUPPLEMENTARY INFORMATION I. Background HUD is committed to meeting the goals...

  4. 76 FR 2407 - Notice of Availability: HUD's Fiscal Year (FY) 2010 NOFA for the Capital Fund Education and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-13

    ... Oversight at 202-708-0667 (this is not a toll-free number) or the NOFA Information Center at 800-HUD-8929 (toll-free). Persons with hearing or speech impairments may access these numbers via TTY by calling the... that you meet the timely receipt requirements. FOR FURTHER INFORMATION CONTACT: Questions...

  5. 76 FR 35881 - Chevron Products Company v. SFPP, L.P.; Notice of Complaint

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-20

    ... Products Company v. SFPP, L.P.; Notice of Complaint Take notice that on June 13, 2011, pursuant to 13(1) of....P. (Respondent) challenging the lawfulness of indexed rate increases filed by SFPP on May 27, 2011... , or call (866) 208-3676 (toll free). For TTY, call (202) 502-8659. Comment Date: 5 p.m. Eastern...

  6. 76 FR 35880 - Chevron Products Company v. SFPP, L.P.; Notice of Complaint

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-20

    ...] Chevron Products Company v. SFPP, L.P.; Notice of Complaint Take notice that on June 13, 2011, pursuant to... system of SFPP, L.P. (Respondent). This complaint is directed at the existing base rates contained in the...Support@ferc.gov , or call (866) 208-3676 (toll free). For TTY, call (202) 502-8659. Comment Date: 5...

  7. 75 FR 63452 - Lobo Pipeline Company L.P.; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... Energy Regulatory Commission Lobo Pipeline Company L.P.; Notice of Baseline Filing October 7, 2010. Take notice that on October 1, 2010, Lobo Pipeline Company L.P. submitted a revised baseline filing of its...Support@ferc.gov , or call (866) 208-3676 (toll free). For TTY, call (202) 502-8659. Comment Date: 5...

  8. 75 FR 37785 - Crosstex North Texas Pipeline, L.P.; Notice of Baseline Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-30

    ... Energy Regulatory Commission Crosstex North Texas Pipeline, L.P.; Notice of Baseline Filing June 23, 2010. Take notice that on June 21, 2010, Crosstex North Texas Pipeline, L.P. submitted a baseline filing of...Support@ferc.gov , or call (866) 208-3676 (toll free). For TTY, call (202) 502-8659. Comment Date: 5...

  9. 78 FR 18973 - Bridgeline Holdings, L.P.; Notice of Petition for Rate Approval

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-28

    ... Energy Regulatory Commission Bridgeline Holdings, L.P.; Notice of Petition for Rate Approval Take notice that on February 28, 2013, as supplemented on March 12, 2013, Bridgeline Holdings, L.P. filed for... free). For TTY, call (202) 502-8659. Comment Date: 5:00 p.m. Eastern Time on Monday, April 1,...

  10. 77 FR 70432 - Magic Valley Pipeline, L.P.; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-26

    ... Energy Regulatory Commission Magic Valley Pipeline, L.P.; Notice of Filing Take notice that on November 15, 2012, Magic Valley Pipeline, L.P. (Magic Valley) filed to revise its Statement of Operating... free). For TTY, call (202) 502-8659. Comment Date: 5:00 p.m. Eastern Time on Tuesday, November 27,...

  11. 76 FR 71037 - Proposed National Toxicology Program (NTP) Review Process for the Report on Carcinogens: Request...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-16

    ... on the NTP Web site ( http://ntp.niehs.nih.gov/go/rocprocess ) prior to the November 29, 2011... Federal Register (76 FR 67200) and is available on the NTP Web site ( http://ntp.niehs.nih.gov/go... the NTP Web site ( http://ntp.niehs.nih.gov/go/rocprocess ). TTY users should contact the Federal...

  12. 76 FR 19357 - FCC To Hold Open Commission Meeting, Thursday, April 7, 2011

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-07

    ... Networks of Damage or Failure of Network Equipment or Severe Overload (PS Docket No. 10-92); Independent... can contact you if we need more information. Last minute requests will be accepted, but may be... 202-418-0530 (voice), 202-418-0432 (tty). Additional information concerning this meeting may...

  13. 78 FR 4060 - Manufactured Home Construction and Safety Standards, Test Procedures for Roof Trusses

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-18

    ...: Effective Date: January 13, 2014. FOR FURTHER INFORMATION CONTACT: Henry S. Czauski, Acting Deputy... through TTY by calling the toll-free Federal Relay Service at 1-800-877-8339. SUPPLEMENTARY INFORMATION: I... higher factor of safety or overload of 2.0 times the design live load should be used to conduct...

  14. 75 FR 44003 - Financial Standards for Housing Agency-Owned Insurance Entities

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-27

    ... . Persons with hearing or speech impairments may access this number through TTY by calling the toll-free... Policy, Programs and Legislative Initiatives, PIH, Department of Housing and Urban Development, 451 7th... Secretary for Policy, Programs, and Legislative Initiatives. BILLING CODE 4210-67-P...

  15. 77 FR 42323 - Notice of Proposed Information Collection for Public Comment; Public Housing Agency (PHA) Lease...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-18

    ..._Pollard@hud.gov . Persons with hearing or speech impairments may access this number through TTY by calling...: Arlette Mussington, Office of Policy, Programs and Legislative Initiatives, PIH, Department of Housing and...-402-4109, (this is not a toll-free number). Persons with hearing or speech impairments may access...

  16. 75 FR 66773 - Notice of Proposed Information Collection for Public Comment; FY 2010 Capital Fund Community and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-29

    ... or speech impairments may access this number through TTY by calling the toll-free Federal Information... numbers are not toll-free.) FOR FURTHER INFORMATION CONTACT: Arlette Mussington, Office of Policy.... Merrie Nichols-Dixon, Acting Deputy Assistant Secretary Office of Policy, Programs, and...

  17. 75 FR 54898 - Notice of Proposed Information Collection for Public Comment: Restrictions on Assistance to...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-09

    ... hearing or speech impairments may access this number through TTY by calling the toll-free Federal..., telephone numbers are not toll-free.) FOR FURTHER INFORMATION CONTACT: Arlette Mussington, Office of Policy...-Dixon, Acting Deputy Assistant Secretary, Office of Policy, Program and Legislative Initiatives....

  18. 75 FR 54353 - Notice of Proposed Information Collection for Public Comment; Notice of Proposed Information...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-07

    ... . Persons with hearing or speech impairments may access this number through TTY by calling the toll-free... of Policy, Programs and Legislative Initiatives, PIH, Department of Housing and Urban Development... for Policy, Programs, and Legislative Initiatives. BILLING CODE 4210-67-P...

  19. 78 FR 74157 - Notice of HUD-Held Multifamily Loan Sale (MLS 2014-1)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-10

    .... Hearing- or speech-impaired individuals may call 202-708-4594 (TTY). These are not toll-free numbers... review of the Mortgage Loan is provided in the BIP. Mortgage Loan Sale Policy HUD reserves the right to... promulgated thereunder. Scope of Notice This notice applies to MLS 2014-1 and does not establish HUD's...

  20. Message transmission efficiency through five telecommunication technologies for signing deaf users.

    PubMed

    Vincent, Claude; Bergeron, François; Hotton, Mathieu; Deaudelin, Isabelle

    2010-01-01

    This cross-sectional research design compares the efficiency of videoconferencing in distance communication for signing deaf persons with that of teletypewriter (TTY)-based telecommunication for the deaf. The efficiency of message transmission was evaluated among 30 signing deaf persons (18 to 65 years) under the six following experimental conditions: (a) Omnitor Allan eC software, (b) Polycom ViaVideo II software, (c) Microsoft Windows Live Messenger software, (d) the D-Link videophone, (e) TTY (written French), and (f) face to face (reference standard). Three timed intelligibility tests and a satisfaction assessment were carried out for each of the experimental conditions. Results showed that videoconferencing technologies offer a better efficacy/time ratio for communication than does TTY. Communication using videoconferencing technologies was very similar to face-to-face communication; this was also true for technologies that are not designed specifically for the deaf population. Equivalent satisfaction levels were observed between TTY and videoconferencing technologies. Microsoft Windows Live Messenger was less preferred due to image fluidity issues.

  1. The Unique Roles of Intrapersonal and Social Factors in Adolescent Smoking Development

    ERIC Educational Resources Information Center

    Defoe, Ivy N.; Semon Dubas, Judith; Somerville, Leah H.; Lugtig, Peter; van Aken, Marcel A. G.

    2016-01-01

    Adolescence is a vulnerable period for the initiation and peak of many harmful risk-taking behaviors such as smoking, which is among the most addictive and deadliest behaviors. Generic metatheories like the theory of triadic influence (TTI) suggest that interrelated risk factors across multiple domains (i.e., intrapersonal and…

  2. 76 FR 6121 - Information Collection; Submission for OMB Review, Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-03

    ... deaf (TTY-TDD) may call (202) 606-3472 between 8:30 a.m. and 5 p.m. Eastern Time, Monday through Friday... Survey which is used by NCCC projects and partnerships office to collect project performance data. Type.../maintenance): None. Dated: January 26, 2011. Charles Davenport, Director of Projects and...

  3. User’s Guide to the SOLAR Semantic Analysis File

    DTIC Science & Technology

    1975-04-30

    ur^ was nbetber it voald be pos?ifcle tc cull tt-i best analysts frcs? t^h^ iit*»iatQi;e# acca ^tlnq all tnnor*tical...the Stanford Research Institute project currently providing direct support to the SDC SUR prcjoct. M APPIL 147 5 14 SYST£ P1 DEVELOPMENT

  4. 36 CFR 1193.3 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 3 2014-07-01 2014-07-01 false Definitions. 1193.3 Section... TELECOMMUNICATIONS ACT ACCESSIBILITY GUIDELINES General § 1193.3 Definitions. Terms used in this part shall have the..., but are not limited to, voice, fax, relay service, TTY, Internet posting, captioning,...

  5. 36 CFR 1193.3 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Definitions. 1193.3 Section... TELECOMMUNICATIONS ACT ACCESSIBILITY GUIDELINES General § 1193.3 Definitions. Terms used in this part shall have the..., but are not limited to, voice, fax, relay service, TTY, Internet posting, captioning,...

  6. 78 FR 11179 - Sunshine Act Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-15

    ... SESSION: 1. Announcement of Notation Votes, and 2. Report on Implementation of the EEOC's Strategic Plan... in the Federal Register, the Commission also provides information about Commission meetings on its... sessions.) Please telephone (202) 663-7100 (voice) and (202) 663-4074 (TTY) at any time for information...

  7. 77 FR 17086 - Section 8 Housing Choice Vouchers: Revised Implementation of the HUD-VA Supportive Housing Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-23

    ... Integrated Service Network (VISN)) to project-base these vouchers in accordance with 24 CFR part 983. Public... hearing impairments may access this number through TTY by calling the toll-free Federal Relay Service at... clinical services provided by the VA through its community medical centers. Since implementation of...

  8. Romanian blood donors screening: is it really necessary and/or mandatory?

    PubMed

    Hâţu, Giorgiana; Brumboiu, Maria Irina; Gorgan, Iuliana Nela; Bocşan, I S

    2013-01-01

    Blood services are required to provide the safest possible products, but no transfusion can ever be totally free of the risk of transfusion transmissible infections (TTI). Over the past decade, the risk of TTI through transfusion has been reduced (e.g. 1 in 300 000 for HBV to 1 in 2 million for HIV). With the introduction in 1999 of sensitive and expensive nucleic acid testing (NAT) technology in some countries, the disease transmission rate and the window period have been significantly reduced, but a remaining concern is the chance that a blood donor will be infected and not detected by such tests. To obtain safe blood and blood components it is important to ensure that the donors are healthy and free from TTI by using a donor selection procedure meticulously made, using a donor questionnaire to assess donor health and safety and for reducing the risk of transmission of infection, in particular for infections for which no suitable screening tests are available. In Romania the prevalence of TTI among donor population is high in comparison with other European Union (EU) countries. This may require significant improvements in the screening process of both donors and donations to minimize the infectious risk.

  9. 78 FR 5430 - Extension of Approval Period for Certain Tests Used in the National Reporting System for Adult...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-25

    ... telephone (TTY), call the Federal Relay Service (FRS), toll free, at 1- 800-877-8339. SUPPLEMENTARY... expiring test and transition to other tests suitable for use in the NRS. Specifically, under the sunset..., during a transition period ending on June 30, 2014. States may use the transition period to select...

  10. 76 FR 1427 - AES Wind Generation, Inc. v. California Independent System Operator Corporation; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-10

    ... Transition Cluster. By this notice, the date for filing answers to the Motion for Stay is shortened to and...Support@ferc.gov , or call (866) 208-3676 (toll free). For TTY, call (202) 502-8659. Comment Date: 5...

  11. 77 FR 48855 - Benefits Payable in Terminated Single-Employer Plans; Interest Assumptions for Paying Benefits

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-15

    ... first FEDERAL REGISTER issue of each #0;week. #0; #0; #0; #0;#0;Federal Register / Vol. 77, No. 158... pension insurance system administered by PBGC. DATES: Effective September 1, 2012. FOR FURTHER INFORMATION... 20005, 202-326-4024. (TTY/TDD users may call the Federal relay service toll-free at 1-800- 877-8339...

  12. 77 FR 15681 - Amendments to the HUD Acquisition Regulation (HUDAR)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-16

    ... Division at 202-402-3055 (this is not a toll-free number). Individuals with speech or hearing impairments may access this number via TTY by calling the Federal Information Relay Service, toll-free, at 800-877... (these are not toll-free numbers). Persons with hearing or speech impairments may access that number...

  13. 77 FR 72368 - Privacy Act of 1974; Notice of a New System of Records, Enterprise Wide Operations Data Store

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-05

    ..., 4th Floor) [The above telephone number is not a toll free number]. A telecommunications device for hearing- and speech-impaired persons (TTY) is available by calling the Federal Information Relay Service's toll-free telephone number (800) 877-8339. SUPPLEMENTARY INFORMATION: Pursuant to the Privacy Act...

  14. 77 FR 73523 - HUD Acquisition Regulations (HUDAR)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-10

    ... (this is not a toll-free number) and fax number 202-708- 8912. Persons with hearing or speech impairments may access Mr. Blocker's telephone number via TTY by calling the toll-free Federal Relay Service... electronically accessible media, either owned by the contractor, subcontractor(s), or employees of the...

  15. 78 FR 5210 - Open Government Initiative: Implementation of the iCERT Labor Certification Registry for the H-1B...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-24

    ...-4312, Washington, DC 20210; Telephone (202) 693-3010 (this is not a toll-free number). Individuals with hearing or speech impairments may access the telephone number above via TTY by calling the toll-free... research and analysis; and Access to important social media platforms for users to stay connected to...

  16. 75 FR 17140 - Sunshine Act; Farm Credit Administration Board; Regular Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-05

    ...: Notice is hereby given, pursuant to the Government in the Sunshine Act (5 U.S.C. 552b(e)(3)), of the..., 2010, from 9 a.m. until such time as the Board concludes its business. FOR FURTHER INFORMATION CONTACT: Roland E. Smith, Secretary to the Farm Credit Administration Board, (703) 883-4009, TTY (703)...

  17. 47 CFR 7.17 - Informal complaints; form and content.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... subpart may be transmitted to the Commission by any reasonable means, e.g., letter, facsimile transmission, telephone (voice/TRS/TTY), Internet e-mail, ASCII text, Internet e-mail, audio-cassette recording, and...), Internet e-mail, ASCII text, audio-cassette recording, braille; or some other method that will...

  18. 7 CFR 510.3 - Requests for records.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Coordinator, Information Staff, ARS, REE, USDA, Mail Stop 5128, 5601 Sunnyside Avenue, Beltsville, MD 20705-5128; Telephone (301) 504-1640 or (301) 504-1655; TTY-VOICE (301) 504-1743; Facsimile (301) 504-1648; e-mail vherberger@ars.usda.gov or shutchison@ars.usda.gov. The FOIA Coordinator is delegated authority...

  19. 47 CFR 7.17 - Informal complaints; form and content.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... subpart may be transmitted to the Commission by any reasonable means, e.g., letter, facsimile transmission, telephone (voice/TRS/TTY), Internet e-mail, ASCII text, Internet e-mail, audio-cassette recording, and...), Internet e-mail, ASCII text, audio-cassette recording, braille; or some other method that will...

  20. 47 CFR 7.17 - Informal complaints; form and content.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... subpart may be transmitted to the Commission by any reasonable means, e.g., letter, facsimile transmission, telephone (voice/TRS/TTY), Internet e-mail, ASCII text, Internet e-mail, audio-cassette recording, and...), Internet e-mail, ASCII text, audio-cassette recording, braille; or some other method that will...

  1. Influence of bright light exposure for several hours during the daytime on cutaneous vasodilatation and local sweating induced by an exercise heat load.

    PubMed

    Aizawa, S; Tokura, H

    1998-09-01

    The aim of the present study was to investigate the effect of exposure to differing light intensities for several hours during the daytime on the cutaneous vasodilatation and local forearm sweat rate induced by exercise. Seven healthy female subjects were exposed to bright light of 6000 lux (bright) or dim light of 100 lux (dim) during the daytime between 0900 hours to 1330 hours, followed by exposure to 150 lux until the test was over at 1600 hours. They spent their time in neutral conditions (29 degrees C, 40% relative humidity) from 0900 hours to 1500 hours, and then exercised on a cycle ergometer for 30 min at 50% maximal physical work capacity. Average tympanic temperatures were significantly lower in bright than in dim from 1133 hours to 1430 hours. The onset of cutaneous vasodilatation and local forearm sweating occurred at significantly lower tympanic temperature (Tty) during exercise after bright than after dim. After exercise, the cessation of forearm sweating and the rapid change of skin blood flow occurred at significantly lower Tty after bright than after dim. It was concluded that exposure to bright light over several hours during the daytime could reduce Tty and shift the threshold Tty for cutaneous vasodilatation and forearm sweating to a lower level.

  2. 77 FR 33980 - National Appeals Office Rules of Procedure

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-08

    ....) Individuals with hearing or speech impairments may access the telephone number above via TTY by calling the... the United States Postal Service or commercial carrier. (4) NAO will presume that documents addressed to an address of record and properly mailed or given to a commercial carrier for delivery...

  3. 77 FR 69870 - Federal Housing Administration (FHA) Healthcare Facility Documents: Revisions and Updates and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-21

    ... number). Individuals with speech or hearing impairments may access this number via TTY by calling the... is not a toll-free number). Persons with hearing or speech disabilities may access this number... such as those regarding the amount of commercial space allowed in a facility or the flood...

  4. 77 FR 21880 - Federal Housing Administration (FHA): Multifamily Accelerated Processing-Enhancing and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-12

    ... (this is not a toll-free number). Individuals with speech or hearing impairments may access this number...-free number). Persons with hearing or speech impairments may access this number through TTY by calling... than in the past, and mixed-use projects with commercial components are more common. Most projects...

  5. 75 FR 70951 - Notice, Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-19

    ... From the Federal Register Online via the Government Publishing Office NATIONAL COUNCIL ON DISABILITY (NCD) Sunshine Act Meetings Notice, Correction Type: Quarterly Meeting. Summary: NCD published a...., Suite 850, Washington, DC 20004; 202-272-2004 (voice), 202-272-2074 TTY; 202-272-2022 Fax. Correction...

  6. 78 FR 45946 - 60-Day Notice of Proposed Information Collection: Owner Certification With HUD's Tenant...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-30

    ... proposal by name and/or OMB Control Number and should be sent to: Colette Pollard, Reports Management... 20410-5000; telephone 202-402-3400 (this is not a toll-free number) or email at Colette.Pollard@hud.gov... impairments may access this number through TTY by calling the toll-free Federal Relay Service at (800)...

  7. Effect of motor unit recruitment on functional vasodilatation in hamster retractor muscle

    PubMed Central

    Van Teeffelen, Jurgen W G E; Segal, Steven S

    2000-01-01

    The effect of motor unit recruitment on functional vasodilatation was investigated in hamster retractor muscle. Recruitment (i.e. peak tension) was controlled with voltage applied to the spinal accessory nerve (high = maximum tension; intermediate = ∼50% maximum; low = ∼25% maximum). Vasodilatory responses (diameter × time integral, DTI) to rhythmic contractions (1 per 2 s for 65 s) were evaluated in first, second and third orderarterioles and in feed arteries. Reciprocal changes in duty cycle (range, 2·5–25 %) effectively maintained the total active tension (tension × time integral, TTI) constant across recruitment levels. With constant TTI and stimulation frequency (40 Hz), DTI in all vessels increased with motor unit recruitment. DTI increased from distal arterioles up through proximal feed arteries. To determine whether the effect of recruitment on DTI was due to increased peak tension, the latter was controlled with stimulation frequency (15, 20 and 40 Hz) during maximum (high) recruitment. With constant TTI, DTI then decreased as peak tension increased. To explore the interaction between recruitment and duty cycle on DTI, each recruitment level was applied at 2.5, 10 and 20 % duty cycle (at 40 Hz). For a given increase in TTI, recruitment had a greater effect on DTI than did duty cycle. Functional vasodilatation in response to rhythmic contractions is facilitated by motor unit recruitment. Thus, vasodilatory responses are determined not only by the total tension produced, but also by the number of active motor units. PMID:10747197

  8. 78 FR 60271 - Mid-Atlantic Hydro, LLC; Notice of Preliminary Permit Application Accepted for Filing and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-01

    ... Hydroelectric Project (Francis Walter Project or project) to be located at the U.S. Army Corps of Engineers... notices of intent must meet the requirements of 18 CFR 4.36. The Commission strongly encourages electronic... , (866) 208-3676 (toll free), or (202) 502- 8659 (TTY). In lieu of electronic filing, please send a...

  9. 78 FR 78354 - Borough of Weatherly; Notice of Preliminary Permit Application Accepted for Filing and Soliciting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-26

    ... Reservoir (Francis Walter Project or project) to be located at the U.S. Army Corps of Engineers' (Corps... electronic filing. Please file comments, motions to intervene, notices of intent, and competing applications....gov , (866) 208-3676 (toll free), or (202) 502- 8659 (TTY). In lieu of electronic filing, please...

  10. 75 FR 13457 - Americans With Disabilities Act (ADA) Accessibility Guidelines for Buildings and Facilities...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-22

    ... Accessibility Guidelines; Electronic and Information Technology Accessibility Standards AGENCY: Architectural... Notice of Proposed Rulemaking (ANPRM) to begin the process of updating its standards for electronic and... (voice); 202- 272-0082 (TTY). Electronic mail address: board.gov ">creagan@access-...

  11. Ethical challenges in voluntary blood donation in Kerala, India.

    PubMed

    Choudhury, L P; Tetali, S

    2007-03-01

    The National Blood Policy in India relies heavily on voluntary blood donors, as they are usually assumed to be associated with low levels of transfusion-transmitted infections (TTIs). In India, it is mandatory to test every unit of blood collected for hepatitis B, hepatitis C, HIV/AIDS, syphilis and malaria. Donors come to the blood bank with altruistic intentions. If donors test positive to any of the five infections, their blood is discarded. Although the blood policy advocates disclosure of TTI status, donors are not, in practice, informed about their results. The onus is on the donor to contact the blood bank. Out of approximately 16 000 donations in the past 2 years, 438 tested positive for TTI, including 107 for HIV. Only 20% of the donors contacted the blood bank; none of them were HIV positive. Disclosure by blood banks of TTI status by telephone or mail has resulted in serious consequences for some donors. Health providers face an ethical dilemma, in the absence of proper mechanisms in place for disclosure of test results, regarding notification to donors who may test positive but remain ignorant of their TTI status. Given the high cost of neglecting to notify infected donors, the authors strongly recommend the use of rapid tests before collecting blood, instead of the current practice, which takes 3 h to obtain results, and disclosure of results directly to the donor by a counsellor, to avoid dropouts and to ensure confidentiality.

  12. Ethical challenges in voluntary blood donation in Kerala, India

    PubMed Central

    Choudhury, L P; Tetali, S

    2007-01-01

    The National Blood Policy in India relies heavily on voluntary blood donors, as they are usually assumed to be associated with low levels of transfusion‐transmitted infections (TTIs). In India, it is mandatory to test every unit of blood collected for hepatitis B, hepatitis C, HIV/AIDS, syphilis and malaria. Donors come to the blood bank with altruistic intentions. If donors test positive to any of the five infections, their blood is discarded. Although the blood policy advocates disclosure of TTI status, donors are not, in practice, informed about their results. The onus is on the donor to contact the blood bank. Out of approximately 16 000 donations in the past 2 years, 438 tested positive for TTI, including 107 for HIV. Only 20% of the donors contacted the blood bank; none of them were HIV positive. Disclosure by blood banks of TTI status by telephone or mail has resulted in serious consequences for some donors. Health providers face an ethical dilemma, in the absence of proper mechanisms in place for disclosure of test results, regarding notification to donors who may test positive but remain ignorant of their TTI status. Given the high cost of neglecting to notify infected donors, the authors strongly recommend the use of rapid tests before collecting blood, instead of the current practice, which takes 3 h to obtain results, and disclosure of results directly to the donor by a counsellor, to avoid dropouts and to ensure confidentiality. PMID:17329382

  13. The Association between Attitude towards the Implementation of Staff Development Training and the Practice of Knowledge Sharing among Lecturers

    ERIC Educational Resources Information Center

    Kassim, Abd. Latif; Raman, Arumugam; Don, Yahya; Daud, Yaakob; Omar, Mohd Sofian

    2015-01-01

    This study was aimed to identify the association of teachers' attitude towards the implementation of Staff Development Training with Knowledge Sharing Practices among the lecturers of the Teacher Training Institution (TTI). In addition, this study was also to examine the differences in attitudes towards the implementation of Staff Development…

  14. 36 CFR 1194.23 - Telecommunications products.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Telecommunications products... Telecommunications products. (a) Telecommunications products or systems which provide a function allowing voice... intermix speech with TTY use. (b) Telecommunications products which include voice...

  15. 77 FR 25105 - Reporting of Ancillary Airline Passenger Revenues

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-27

    ... processing and accounting for baggage and wheelchairs. This information is critical to determining the cost... Department contacts noted below at least ten (10) calendar days prior to the meeting. FOR FURTHER INFORMATION... (phone), 202-366-7152 (fax), Blane.Workie@dot.gov . TTY users may reach these individuals via the...

  16. Sequential Processing and the Matching-Stimulus Interval Effect in ERP Components: An Exploration of the Mechanism Using Multiple Regression

    PubMed Central

    Steiner, Genevieve Z.; Barry, Robert J.; Gonsalvez, Craig J.

    2016-01-01

    In oddball tasks, increasing the time between stimuli within a particular condition (target-to-target interval, TTI; nontarget-to-nontarget interval, NNI) systematically enhances N1, P2, and P300 event-related potential (ERP) component amplitudes. This study examined the mechanism underpinning these effects in ERP components recorded from 28 adults who completed a conventional three-tone oddball task. Bivariate correlations, partial correlations and multiple regression explored component changes due to preceding ERP component amplitudes and intervals found within the stimulus series, rather than constraining the task with experimentally constructed intervals, which has been adequately explored in prior studies. Multiple regression showed that for targets, N1 and TTI predicted N2, TTI predicted P3a and P3b, and Processing Negativity (PN), P3b, and TTI predicted reaction time. For rare nontargets, P1 predicted N1, NNI predicted N2, and N1 predicted Slow Wave (SW). Findings show that the mechanism is operating on separate stages of stimulus-processing, suggestive of either increased activation within a number of stimulus-specific pathways, or very long component generator recovery cycles. These results demonstrate the extent to which matching-stimulus intervals influence ERP component amplitudes and behavior in a three-tone oddball task, and should be taken into account when designing similar studies. PMID:27445774

  17. The Illicit Use of Prescription Stimulants on College Campuses

    ERIC Educational Resources Information Center

    Bavarian, Niloofar; Flay, Brian R.; Ketcham, Patricia L.; Smit, Ellen

    2015-01-01

    The illicit use of prescription stimulants (IUPS) is a substance use behavior that remains prevalent on college campuses. As theory can guide research and practice, we provide a systematic review of the college-based IUPS epidemiological literature guided by one ecological framework, the theory of triadic influence (TTI). We aim to assess…

  18. 29 CFR 4000.4 - Where do I file my submission?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... forms, or call our Customer Service Center (1-800-400-7242 for participants, or 1-800-736-2444 for practitioners; TTY/TDD users may call the Federal relay service toll-free at 1-800-877-8339 and ask to...

  19. 29 CFR 4000.4 - Where do I file my submission?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... forms, or call our Customer Service Center (1-800-400-7242 for participants, or 1-800-736-2444 for practitioners; TTY/TDD users may call the Federal relay service toll-free at 1-800-877-8339 and ask to...

  20. Fully anisotropic 3-D EM modelling on a Lebedev grid with a multigrid pre-conditioner

    NASA Astrophysics Data System (ADS)

    Jaysaval, Piyoosh; Shantsev, Daniil V.; de la Kethulle de Ryhove, Sébastien; Bratteland, Tarjei

    2016-12-01

    We present a numerical algorithm for 3-D electromagnetic (EM) simulations in conducting media with general electric anisotropy. The algorithm is based on the finite-difference discretization of frequency-domain Maxwell's equations on a Lebedev grid, in which all components of the electric field are collocated but half a spatial step staggered with respect to the magnetic field components, which also are collocated. This leads to a system of linear equations that is solved using a stabilized biconjugate gradient method with a multigrid preconditioner. We validate the accuracy of the numerical results for layered and 3-D tilted transverse isotropic (TTI) earth models representing typical scenarios used in the marine controlled-source EM method. It is then demonstrated that not taking into account the full anisotropy of the conductivity tensor can lead to misleading inversion results. For synthetic data corresponding to a 3-D model with a TTI anticlinal structure, a standard vertical transverse isotropic (VTI) inversion is not able to image a resistor, while for a 3-D model with a TTI synclinal structure it produces a false resistive anomaly. However, if the VTI forward solver used in the inversion is replaced by the proposed TTI solver with perfect knowledge of the strike and dip of the dipping structures, the resulting resistivity images become consistent with the true models.

  1. 76 FR 7837 - Ryan, Robert M.; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-11

    ... Energy Regulatory Commission Ryan, Robert M.; Notice of Filing Take notice that on December 31, 2010, Robert M. Ryan submitted for filing, an application for authority to hold interlocking positions... TTY, call (202) 502-8659. Comment Date: 5 p.m. Eastern Time on February 22, 2011. Dated: February...

  2. 78 FR 25264 - Southern Star Central Gas Pipeline, Inc.; Notice of Request Under Blanket Authorization

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-30

    ... Energy Regulatory Commission Southern Star Central Gas Pipeline, Inc.; Notice of Request Under Blanket Authorization Take notice that on April 16, 2013, Southern Star Central Gas Pipeline, Inc. (Southern Star), 4700...) 208-3676 (toll free). For TTY, call (202) 502-8659. Specifically, Southern Star proposes to abandon...

  3. 78 FR 76108 - Sunshine Act Meeting Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-16

    ... person. ] Individuals may submit written comments to jmauk@cns.gov subject line: DECEMBER 2013 CNCS BOARD... accommodation should notify Ida Green at igreen@cns.gov or 202- 606-6861 by 5 p.m. (ET) on December 13, 2013...-606- 3460. TTY: 800-833-3722. Email: jmauk@cns.gov . Dated: December 11, 2013. Valerie Green,...

  4. 78 FR 27369 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-10

    ...@cns.gov subject line: MAY 2013 CNCS BOARD MEETING by 4:00 p.m. (ET) on May 10, 2013. Individuals.... Anyone who needs an interpreter or other accommodation should notify Ida Green at igreen@cns.gov or 202..., DC 20525. Phone: (202) 606-6615. Fax: (202) 606-3460. TTY: (800) 833-3722. Email:...

  5. 76 FR 24045 - Notice of HUD-Held Multifamily Loan Sale (MLS 2011-1)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-29

    ..., extension 3927. Hearing- or speech-impaired individuals may call 202- 708-4594 (TTY). These are not toll... reserved the right to add Mortgage Loans to or delete Mortgage Loans from MLS 2011-1 at any time prior to the Award Date. HUD also reserved the right to reject any and all bids, in whole or in part,...

  6. 76 FR 47226 - Notice of HUD-Held Multifamily Loan Sale (MLS 2011-2)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-04

    ..., extension 3927. Hearing- or speech-impaired individuals may call 202-708-4594 (TTY). These are not toll-free... reserved the right to add Mortgage Loans to or delete Mortgage ] Loans from MLS 2011-2 at any time prior to the Award Date. HUD also reserved the right to reject any and all bids, in whole or in part,...

  7. 75 FR 51437 - Notice of Request for Extension of a Currently Approved Information Collection (Advanced Meat...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-20

    ... collection techniques, or other forms of information technology. Comments may be sent to both FSIS, at the... (Braille, large print, audiotape, etc.) should contact USDA's Target Center at 202-720-2600 (voice and TTY... communicated via Listserv, a free e-mail subscription service consisting of industry, trade, and farm...

  8. 76 FR 53145 - Filing Procedures for Employment Authorization and Automatic Extension of Existing Employment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-25

    ...://www.uscis.gov , or call the USCIS National Customer Service Center at 1-800-375-5283 (TTY 1-800-767..., what documentation may I show to my employer as proof of employment authorization and identity when... identity and employment authorization of all new employees by using Form I-9. Within three days of hire,...

  9. 41 CFR Appendix A to Part 60 - 741-Guidelines on a Contractor's Duty To Provide Reasonable Accommodation

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... three areas in which reasonable accommodations may be necessary: (1) Accommodations in the application... vocational rehabilitation agency) or if Federal, State, or local tax deductions or tax credits are available...-6820 (TTY)), the Job Accommodation Network (JAN)—a service of the U.S. Department of Labor's Office...

  10. 78 FR 21396 - Notice of a Federal Advisory Committee Meeting: Manufactured Housing Consensus Committee...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-10

    ... toll-free number). Persons who have difficulty hearing or speaking may access this number via TTY by... organized and carry out its business in a manner that guarantees a fair opportunity for the expression and...@nfpa.org . Written comments are encouraged. The MHCC Structural and Design Subcommittee strives...

  11. 41 CFR Appendix A to Part 60 - 250-Guidelines on a Contractor's Duty To Provide Reasonable Accommodation

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... areas in which reasonable accommodations may be necessary: (1) Accommodations in the application process... Veterans Affairs or a state vocational rehabilitation agency, or if Federal, state or local tax deductions...-6820 (TTY)), the Job Accommodation Network (JAN) operated by the Office of Disability Employment...

  12. 41 CFR Appendix A to Part 60 - 250-Guidelines on a Contractor's Duty To Provide Reasonable Accommodation

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... areas in which reasonable accommodations may be necessary: (1) Accommodations in the application process... Veterans Affairs or a state vocational rehabilitation agency, or if Federal, state or local tax deductions...-6820 (TTY)), the Job Accommodation Network (JAN) operated by the Office of Disability Employment...

  13. 41 CFR Appendix A to Part 60 - 250-Guidelines on a Contractor's Duty To Provide Reasonable Accommodation

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... areas in which reasonable accommodations may be necessary: (1) Accommodations in the application process... Veterans Affairs or a state vocational rehabilitation agency, or if Federal, state or local tax deductions...-6820 (TTY)), the Job Accommodation Network (JAN) operated by the Office of Disability Employment...

  14. 75 FR 30831 - Agency Information Collection Activities; Submission for OMB Review; Proposed Collection; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-02

    ... INFORMATION CONTACT: Mr. Paul Ledvina at the Office of Government Ethics; telephone: 202-482-9247; TTY: 800-877-8339; FAX: 202-482-9237; E-mail: paul.ledvina@oge.gov . An electronic copy of the SF 278 is... obtained, without charge, by contacting Mr. Ledvina. SUPPLEMENTARY INFORMATION: Title: Executive...

  15. 78 FR 56704 - Agency Information Collection Activities; Submission for OMB Review; Proposed Collection; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-13

    ... INFORMATION CONTACT: Mr. Paul D. Ledvina at the U.S. Office of Government Ethics; telephone: 202-482-9247; TTY: 800-877-8339; FAX: 202-482-9237; Email: paul.ledvina@oge.gov . An electronic copy of the OGE Form 201... proposed modified form may be obtained, without charge, by contacting Mr. Ledvina. An automated version...

  16. 75 FR 13287 - Proposed Collection; Comment Request for an Unmodified SF 278 Executive Branch Personnel Public...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-19

    ... Avenue, NW., Washington, DC 20005-3917, Attention: Paul D. Ledvina, Records Officer. FOR FURTHER INFORMATION CONTACT: Mr. Ledvina at the Office of Government Ethics; telephone: 202-482-9247; TTY: 800-877-8339; FAX: 202-482-9237; E-mail: paul.ledvina@oge.gov . An electronic copy of the SF 278 is...

  17. 78 FR 29753 - Agency Information Collection Activities; Proposed Collection; Comment Request for an Unmodified...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-21

    ... 500, 1201 New York Avenue NW., Washington, DC 20005-3917, Attention: Paul D. Ledvina, Agency Clearance Officer. FOR FURTHER INFORMATION CONTACT: Mr. Ledvina at the Office of Government Ethics; telephone: 202-482-9247; TTY: 800-877-8339; FAX: 202-482-9237; Email: paul.ledvina@oge.gov . An electronic copy...

  18. 75 FR 5324 - Agency Information Collection Activities; Submission for OMB Review; Proposed Collection; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-02

    ... . FOR FURTHER INFORMATION CONTACT: Paul Ledvina at the Office of Government Ethics; telephone: 202-482-9247; TTY: 800-877-8339; FAX: 202-482-9237; E-mail: paul.ledvina@oge.gov . An electronic copy of the... paper copy may also be obtained, without charge, by contacting Mr. Ledvina. SUPPLEMENTARY...

  19. 75 FR 16809 - Agency Information Collection Activities; Submission for OMB Review; Proposed Collection; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-02

    ... INFORMATION CONTACT: Paul Ledvina at the Office of Government Ethics; telephone: 202-482-9247; TTY: 800-877-8339; FAX: 202-482-9237; E-mail: paul.ledvina@oge.gov . An electronic copy of the OGE Form 450 is... obtained, without charge, by contacting Mr. Ledvina. SUPPLEMENTARY INFORMATION: Title: Executive...

  20. 75 FR 3905 - Proposed Collection; Comment Request for an Unmodified OGE Form 450 Executive Branch Confidential...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-25

    ..., DC 20005-3917, Attention: Paul D. Ledvina, Records Officer. FOR FURTHER INFORMATION CONTACT: Mr. Ledvina at the Office of Government Ethics; telephone: 202-482-9247; TTY: 800-877-8339; FAX: 202-482-9237; E-mail: paul.ledvina@oge.gov . An electronic copy of the OGE Form 450 is available in the...

  1. 77 FR 76293 - Agency Information Collection Activities; Submission for OMB Review; Proposed Collection; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-27

    ...., Washington, DC 20005-3917, Attention: Paul D. Ledvina, Agency Clearance Officer. FOR FURTHER INFORMATION CONTACT: Mr. Ledvina at the U.S. Office of Government Ethics; telephone: 202-482-9247; TTY: 800-877-8339... charge, by contacting Mr. Ledvina. SUPPLEMENTARY INFORMATION: The Office of Government Ethics intends...

  2. 78 FR 48621 - Service Rules for Advanced Wireless Services in the 2000-2020 MHz and 2180-2200 MHz Bands, etc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-09

    ... of effective date. SUMMARY: In this document, the Commission announces that the Office of Management... Consumer and Governmental Affairs Bureau at (202) 418-0530 (voice), (202) 418-0432 (TTY). Synopsis As....73(d), which would not be effective until approved by the Office of Management and Budget....

  3. 75 FR 37752 - Measuring Progress on Food Safety: Current Status and Future Directions; Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-30

    ..., Room 2-2127, George Washington Carver Center, 5601 Sunnyside Avenue, Mailstop 5474, Beltsville, MD..., in Washington, DC (75 FR 9232). The public meetings announced in this notice are extensions of that...., Washington, DC 20250-9410 or call 202-720-5964 (voice and TTY). USDA is an equal opportunity provider...

  4. 76 FR 6572 - Non-Ambulatory Disabled Veal Calves and Other Non-Ambulatory Disabled Livestock at Slaughter...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-07

    ... Agriculture (USDA), FSIS, Room 2-2127, George Washington Carver Center, 5601 Sunnyside Avenue, Beltsville, MD..., FSIS, U.S. Department of Agriculture, 1400 Independence Avenue, SW., Washington, DC 20250-3700, (202... Independence Avenue, SW., Washington, DC 20250-9410 or call 202-720-5964 (voice and TTY). Additional...

  5. 75 FR 19645 - Enterprise Texas Pipeline LLC; Notice of Petition for Rate Approval

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-15

    ....6090 per MMBtu for Rate Zone 1--Legacy Assets and $0.6744 for Rate Zone 2--Sherman Extension Facilities..., please e-mail FERCOnlineSupport@ferc.gov , or call (866) 208-3676 (toll free). For TTY, call (202)...

  6. 49 CFR 577.5 - Notification pursuant to a manufacturer's decision.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... address is in either the Commonwealth of Puerto Rico or the Canal Zone shall be written in both English... the toll-free Vehicle Safety Hotline at 1-888-327-4236 (TTY: 1-800-424-9153); or go to...

  7. Improved Labeling of L.P. Bases in Networks

    DTIC Science & Technology

    1975-10-01

    34NETGEN - A Program for Generating Large Scale (Un) Capacitated Assignment, Transportation and Minimun Cost Flow Network Problems." Management...OEsCHiPTivt NOrt , T), pf i^t rr;K.f f and, inc/u.M ve dates) tti&i. /rtju g^mmj WmFK l(l$l$ 6 REPORT DATE August 1974(Revised October

  8. 76 FR 72203 - Voltage Coordination on High Voltage Grids; Notice of Reliability Workshop Agenda

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-22

    ... improvements to dispatch and voltage control software could improve reliability and market efficiency. This... existing and emerging software to improve coordination and optimization of the Bulk-Power System from a... free 1-(866) 208- 3372 (voice) or (202) 208-1659 (TTY), or send a FAX to (202) 208-2106 with...

  9. 76 FR 76917 - Homeless Management Information Systems Requirements

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-09

    ... Regulations Division at (202) 708-3055 (this is not a toll-free number). Individuals with speech or hearing... toll-free number). Hearing- and speech-impaired persons may access this number through TTY by calling the Federal Information Relay Service at (800) 877-8339 (this is a toll-free number)....

  10. 78 FR 34897 - Final Priorities; National Institute on Disability and Rehabilitation Research-Disability and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-11

    ... (TTY), call the Federal Relay Service (FRS), toll free, at 1- 800-877-8339. SUPPLEMENTARY INFORMATION...; technology interfaces; computer systems; software; and networks for individuals with disabilities. The RERC... published in the Federal Register. Free Internet access to the official edition of the Federal Register...

  11. 76 FR 70721 - Voltage Coordination on High Voltage Grids; Notice of Staff Workshop

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-15

    ... software could improve reliability and market efficiency. The workshop will address how entities currently coordinate economic dispatch and voltage control and the capability of existing and emerging software to... email to accessibility@ferc.gov or call toll free 1-(866) 208- 3372 (voice) or (202) 208-1659 (TTY),...

  12. 78 FR 66375 - Announcement of Funding Awards for the McKinney-Vento HMIS Technical Assistance, Fiscal Year 2013

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-05

    ... not a toll-free number). Persons with speech or hearing impairments may access this telephone number via TTY by calling the toll-free Federal Information Relay Service during working hours at 800-877... Care, including operation and management of the software, and data collection for Annual...

  13. 78 FR 21930 - Aquenergy Systems, Inc.; Notice of Intent To File License Application, Filing of Pre-Application...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-12

    ... Process. k. With this notice, we are initiating informal consultation with: (a) The U.S. Fish and Wildlife... TTY, (202) 502-8659. A copy is also available for inspection and reproduction at the address in..., 2015. p. Register online at http://www.ferc.gov/docs-filing/esubscription.asp to be notified via...

  14. Imaging tilted transversely isotropic media with a generalised screen propagator

    NASA Astrophysics Data System (ADS)

    Shin, Sung-Il; Byun, Joongmoo; Seol, Soon Jee

    2015-01-01

    One-way wave equation migration is computationally efficient compared with reverse time migration, and it provides a better subsurface image than ray-based migration algorithms when imaging complex structures. Among many one-way wave-based migration algorithms, we adopted the generalised screen propagator (GSP) to build the migration algorithm. When the wavefield propagates through the large velocity variation in lateral or steeply dipping structures, GSP increases the accuracy of the wavefield in wide angle by adopting higher-order terms induced from expansion of the vertical slowness in Taylor series with each perturbation term. To apply the migration algorithm to a more realistic geological structure, we considered tilted transversely isotropic (TTI) media. The new GSP, which contains the tilting angle as a symmetric axis of the anisotropic media, was derived by modifying the GSP designed for vertical transversely isotropic (VTI) media. To verify the developed TTI-GSP, we analysed the accuracy of wave propagation, especially for the new perturbation parameters and the tilting angle; the results clearly showed that the perturbation term of the tilting angle in TTI media has considerable effects on proper propagation. In addition, through numerical tests, we demonstrated that the developed TTI-GS migration algorithm could successfully image a steeply dipping salt flank with high velocity variation around anisotropic layers.

  15. 77 FR 44610 - Enbridge Pipelines (North Texas) L.P.; Notice of Compliance Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-30

    ... Federal Energy Regulatory Commission Enbridge Pipelines (North Texas) L.P.; Notice of Compliance Filing Take notice that on July 13, 2012, Enbridge Pipelines (North Texas) L.P. filed a revised Statement of... TTY, call (202) 502-8659. Comment Date: 5:00 p.m. Eastern Time on Monday, July 30, 2012. Dated:...

  16. 76 FR 11780 - Emergency Access Advisory Committee; Announcement of Date of Next Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-03

    ... have a briefing on non-voice emergency services. DATES: The Committee's next meeting will take place on... King, Consumer and Governmental Affairs Bureau, Federal Communications Commission, 202-418-2284 (voice...-0530 (voice), 202-418-0432 (TTY). To request materials in accessible formats for people...

  17. Talking with Children: Tips for Caregivers, Parents, and Teachers during Infectious Disease Outbreaks

    MedlinePlus

    ... Distress Helpline Toll-Free: 1-800-985-5990 (English and español) SMS: Text TalkWithUs to 66746 SMS ( ... al 66746 TTY: 1-800-846-8517 Website (English) : http: / / www. disasterdistress. samhsa. gov Website (español) : http: / / ...

  18. SOCIO-EMOTIONAL AND CHARACTER DEVELOPMENT: A Theoretical Orientation.

    PubMed

    Snyder, Frank J

    More and more researchers are studying socio-emotional and character development (SECD). The rise and progress in SECD research is encouraging, but there is a critical issue with such a multidisciplinary and fast-developing field: SECD research and evaluation can be more consistent to prevent heterogeneity in definitions and disparate theoretical, measurement, and program models. After summarizing SECD-related literature, I recommend the theory of triadic influence (TTI) as a force to generate consistency and a resource to assist in guiding the design and evaluation of SECD-related programs. The theory fills a gulf in the literature that seeks an ecological theory aligned with SECD-related programs and etiology. The recommendation of the TTI stems from 3 main advantages: (1) The TTI integrates a full range of risk and protective factors in a detailed mediation and moderation framework; (2) it takes a comprehensive view of all the stakeholders in the educational system (i.e., youth, schools, families, and communities); (3) and its utility has been substantiated by empirical evidence from a variety of fields. I discuss applications of the TTI in SECD-related work and suggest improvements for etiology research and the design and evaluation of SECD programs.

  19. 76 FR 63601 - Agenda and Notice of Public Meeting of the Louisiana Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-13

    ... p.m. and adjourn at approximately 5 p.m. on Monday, November 7, 2011. The purpose of this meeting is... conference call number and contact name Farella E. Robinson. To ensure that the Commission secures an... Central Regional Office and TTY/TDD telephone number, by 4 p.m. on November 1, 2011. Members of the...

  20. 75 FR 57947 - Auction of VHF Commercial Television Station Construction Permits Scheduled for February 15, 2011...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-23

    ... page at http://www.fcc.gov/cgb/ecfs/ . I. Introduction 1. The Wireless Telecommunications and the Media... TTY: 202-418-0432. The Wireless Telecommunications Bureau requests that a copy of all comments and... INFORMATION CONTACT: Wireless Telecommunications Bureau, Auctions and Spectrum Access Division: For...

  1. 77 FR 5481 - Codex Alimentarius Commission: Meeting of the Codex Committee on Contaminants in Food

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-03

    ... Plans. Editorial Amendments to the General Standard for Contaminants and Toxins in Foods and Feeds... discrimination, write USDA, Office of the Assistant Secretary for Civil Rights, 1400 Independence Avenue SW., Washington, DC 20250-9410 or call (202) 720-5964 (voice and TTY). USDA is an equal opportunity provider...

  2. 77 FR 45353 - Privacy Act of 1974; Amendment to System of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-31

    ...: Kerri A. Cox, Privacy Officer. Mail, Hand Delivery/Courier: Office of Government Ethics, Suite 500, 1201 New York Avenue NW., Washington, DC 20005-3917, Attention: Kerri A. Cox, Privacy Officer. FOR FURTHER INFORMATION CONTACT: Ms. Cox at the Office of Government Ethics; telephone: 202-482-9312; TTY:...

  3. 78 FR 75368 - 60-Day Notice of Proposed Information Collection: HUD Multifamily Energy Assessment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-11

    ... URBAN DEVELOPMENT 60-Day Notice of Proposed Information Collection: HUD Multifamily Energy Assessment...; telephone 202-402-3400 (this is not a toll-free number) or email at Colette.Pollard@hud.gov for a copy of... access this number through TTY by calling the toll-free Federal Relay Service at (800) 877-8339. ]...

  4. 76 FR 18210 - Texas Eastern Transmission, LP; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-01

    ... abandon in place two inactive supply laterals designated as Line 41-B-1 and Line 41-B-1- A. The..., filed with the Federal Energy Regulatory Commission (Commission) an application under section 7(b) of... TTY, (202) 502-8659. Questions regarding the application may be directed to Berk Donaldson,...

  5. 78 FR 73965 - Manufactured Home Construction and Safety Standards

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-09

    ...-free number). Persons with hearing or speech impairments may access this number through TTY by calling... sizing of equipment indicating the most extreme temperatures rather than the actual heating design temperature. The commenter submitted that the wide variance in temperature creates over-compensation in...

  6. 75 FR 43446 - Nondiscrimination on the Basis of Disability in State and Local Government Services...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-26

    ... from cell phones or pagers. See Enforcing the ADA, Update April, September 2009, page 12, available at... phone, and the call taker types back via TTY to the caller. VCO can be accomplished with standard stand... devices, including ``smart'' phones, as well as computers (including computers with Web cams)...

  7. 76 FR 67478 - Bloodborne Pathogens Standard; Extension of the Office of Management and Budget's (OMB) Approval...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-01

    ... at (202) 693- 1648. Mail, hand delivery, express mail, messenger, or courier service: When using this..., 200 Constitution Avenue NW., Washington, DC 20210. Deliveries (hand, express mail, messenger, and... delivery, messenger or courier service, please contact the OSHA Docket Office at (202) 693-2350, (TTY...

  8. 78 FR 16808 - Connect America Fund; High-Cost Universal Service Support

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-19

    ... INFORMATION CONTACT: Heidi Lankau, Wireline Competition Bureau, (202) 418-2876 or TTY: (202) 418-0484. ] SUPPLEMENTARY INFORMATION: This is a summary of the Commission's Sixth Order on Reconsideration and Memorandum... consumers who pay into the universal service fund. Modernizing these systems, the Commission concluded,...

  9. 75 FR 61479 - Kendall Head Tidal Energy Project; Notice of Preliminary Permit Application Accepted for Filing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-05

    ... kilowatts; (2) an anchoring support structure; (3) a mooring system; (4) a 2,700-foot-long submersible cable... comments, click on ``Quick Comment.'' For assistance, please contact FERC Online Support at FERCOnlineSupport@ferc.gov ; call toll-free at (866) 208-3676; or, for TTY, contact (202) 502-8659. Although...

  10. 76 FR 35233 - Notice of Funding Availability (NOFA) for HUD's Fiscal Year 2011; Housing Opportunities for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-16

    ... examining and comprehensively integrating local services for coordinating and streamlining where possible the delivery of those services in your community. The notice providing information regarding the... impairments may access these numbers via TTY by calling the Federal Information Relay Service at 800-877-...

  11. 75 FR 63848 - Notice of Availability: Notice of Funding Availability (NOFA) for HUD's Fiscal Year (FY) 2010...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-18

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  12. 78 FR 16262 - J.P. Morgan Ventures Energy Corporation; Supplemental Notice That Initial Market-Based Rate...

    Federal Register 2010, 2011, 2012, 2013, 2014

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    ... Energy Regulatory Commission J.P. Morgan Ventures Energy Corporation; Supplemental Notice That Initial... notice in the above-referenced proceeding, of J.P. Morgan Ventures Energy Corporation's application for... . or call (866) 208-3676 (toll free). For TTY, call (202) 502-8659. Dated: March 7, 2013. Nathaniel...

  13. 78 FR 70244 - Electronic Interim Assistance Reimbursement Program

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    2013-11-25

    ... or filing for benefits, call our national toll-free number, 1-800-772-1213, or TTY 1-800-325-0778, or... INFORMATION: Background To be eligible for benefits from the SSI program, a person must be age 65 or older... receive SSI benefit payments, and we pay SSI recipients.\\2\\ If we determine that a claimant is eligible...

  14. 76 FR 4110 - Sunshine Act Meeting; FCC To Hold Open Commission Meeting Tuesday, January 25, 2011

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  15. 78 FR 7659 - Revised Medical Criteria for Evaluating Congenital Disorders That Affect Multiple Body Systems

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    2013-02-04

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  16. 76 FR 66315 - Notice of Proposed Information Collection for Public Comment for the Family Unification Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-26

    ...-3400, (this is not a toll free number) or e-mail Ms. Pollard at Colette.Pollard@hud.gov for a information on the data collected. Persons with hearing or speech impairments may access this number through TTY by calling the toll-free Federal Information Relay Service at (800) 877-8339. (Other than the...

  17. 78 FR 59890 - Qualified Mortgage Definition for HUD Insured and Guaranteed Single Family Mortgages

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    2013-09-30

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    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-02

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  19. 77 FR 22583 - Allocations, Common Application, Waivers, and Alternative Requirements for Community Development...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-16

    ... speech impairments may access this number via TTY by calling the Federal Relay Service at 800-877-8339... telephone numbers are not toll-free.) SUPPLEMENTARY INFORMATION: Table of Contents I. Allocations II. Use of... CDBG disaster recovery funds, the following expedited steps are necessary: Grantee adopts...

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    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-17

    ...-402-3400 (this is not a toll free number), or e-mail Ms. Pollard at Colette.Pollard@hud.gov for information on the data collected. Persons with hearing or speech impairments may access this number through TTY by calling the toll-free Federal Information Relay Service at (800) 877-8339. (Other than the...

  1. 50 CFR 226.218 - Critical habitat for the U.S. DPS of smalltooth sawfish (Pristis pectinata).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Unit and the southern unit is the Ten Thousand Islands/Everglades (TTI/E) Unit. The units encompass... Charlotte Harbor, Gasparilla Sound, Pine Island Sound, Matlacha Pass, San Carlos Bay, Estero Bay, and the... and in Gasparilla Sound by the SR-771 Bridge. The COLREGS-72 lines between Gasparilla Island,...

  2. 50 CFR 226.218 - Critical habitat for the U.S. DPS of smalltooth sawfish (Pristis pectinata).

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Unit and the southern unit is the Ten Thousand Islands/Everglades (TTI/E) Unit. The units encompass... Charlotte Harbor, Gasparilla Sound, Pine Island Sound, Matlacha Pass, San Carlos Bay, Estero Bay, and the... and in Gasparilla Sound by the SR-771 Bridge. The COLREGS-72 lines between Gasparilla Island,...

  3. 50 CFR 226.218 - Critical habitat for the U.S. DPS of smalltooth sawfish (Pristis pectinata).

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Unit and the southern unit is the Ten Thousand Islands/Everglades (TTI/E) Unit. The units encompass... Charlotte Harbor, Gasparilla Sound, Pine Island Sound, Matlacha Pass, San Carlos Bay, Estero Bay, and the... and in Gasparilla Sound by the SR-771 Bridge. The COLREGS-72 lines between Gasparilla Island,...

  4. Electronic Prescribing

    MedlinePlus

    ... Do you prescribe electronically?” For more information about electronic prescribing, call 1-800-MEDICARE (1-800-633- ... TTY users should call 1-877-486-2048 . Electronic eRx Prescribing I went to the pharmacy, and ...

  5. 77 FR 18258 - Notice of FHA Debenture Call

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-27

    ... URBAN DEVELOPMENT Notice of FHA Debenture Call AGENCY: Office of the Assistant Secretary for Housing--Federal Housing Commissioner, HUD. ACTION: Notice. SUMMARY: This Notice announces a debenture call of... impairments may access this number through TTY by calling the toll-free Federal Relay Service at...

  6. Electrophysiology of Memory-Updating Differs with Age

    PubMed Central

    Steiner, Genevieve Z.; Gonsalvez, Craig J.; De Blasio, Frances M.; Barry, Robert J.

    2016-01-01

    In oddball tasks, the P3 component of the event-related potential systematically varies with the time between target stimuli—the target-to-target interval (TTI). Longer TTIs result in larger P3 amplitudes and shorter latencies, and this pattern of results has been linked with working memory-updating processes. Given that working memory and the P3 have both been shown to diminish with age, the current study aimed to determine whether the linear relationship between P3 and TTI is compromised in healthy aging by comparing TTI effects on P3 amplitudes and latencies, and reaction time (RT), in young and older adults. Older adults were found to have an overall reduction in P3 amplitudes, longer latencies, an anterior shift in topography, a trend toward slower RTs, and a flatter linear relationship between P3 and TTI than young adults. Results suggest that the ability to maintain templates in working memory required for stimulus categorization decreases with age, and that as a result, neural compensatory mechanisms are employed. PMID:27378908

  7. Electrophysiology of Memory-Updating Differs with Age.

    PubMed

    Steiner, Genevieve Z; Gonsalvez, Craig J; De Blasio, Frances M; Barry, Robert J

    2016-01-01

    In oddball tasks, the P3 component of the event-related potential systematically varies with the time between target stimuli-the target-to-target interval (TTI). Longer TTIs result in larger P3 amplitudes and shorter latencies, and this pattern of results has been linked with working memory-updating processes. Given that working memory and the P3 have both been shown to diminish with age, the current study aimed to determine whether the linear relationship between P3 and TTI is compromised in healthy aging by comparing TTI effects on P3 amplitudes and latencies, and reaction time (RT), in young and older adults. Older adults were found to have an overall reduction in P3 amplitudes, longer latencies, an anterior shift in topography, a trend toward slower RTs, and a flatter linear relationship between P3 and TTI than young adults. Results suggest that the ability to maintain templates in working memory required for stimulus categorization decreases with age, and that as a result, neural compensatory mechanisms are employed.

  8. 75 FR 26941 - Information Collection; Submission for OMB Review, Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-13

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  9. 78 FR 61341 - Proposed Information Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-03

    ... assessed. Individuals who use a telecommunications device for the deaf (TTY-TDD) may call (202) 565-2799... information collection request in order to apply for funding through these grant competitions. Copies of the... instructions will be used by applicants for funding through AmeriCorps State and National grant...

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    Federal Register 2010, 2011, 2012, 2013, 2014

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  11. 77 FR 44220 - Information Collection; Submission for OMB Review, Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

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    ...) entitled Senior Corps Grant Application for review and approval in accordance with the Paperwork Reduction... documentation, may be obtained by calling the Corporation for National and Community Service, Wanda Carney, at... deaf (TTY-TDD) may call 1-800-833- 3722 between 8 a.m. and 8 p.m. Eastern Time, Monday through...

  12. 77 FR 11109 - Reactive Power Resources; Notice of Technical Conference

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-24

    ... interconnecting asynchronous generators and raises questions concerning the need and efficacy of continuing the... by which reactive power is currently secured such as through self-supply; and how a technology that... accessibility@ferc.gov or call toll free 1-866-208- 3372 (voice) or 202-208-8659 (TTY); or send a fax to...

  13. Seroprevalence and trends in transfusion transmitted infections among blood donors in a university hospital blood bank: a 5 year study.

    PubMed

    Pallavi, P; Ganesh, C K; Jayashree, K; Manjunath, G V

    2011-03-01

    Blood is life. Transfusion of blood and blood components, as a specialized modality of patient management saves millions of lives worldwide each year and reduce morbidity. It is well known that blood transfusion is associated with a large number of complications, some are only trivial and others are potentially life threatening, demanding for meticulous pretransfusion testing and screening particularly for transfusion transmissible infections (TTI). These TTI are a threat to blood safety. The priority objective of BTS is thus to ensure safety, adequacy, accessibility and efficiency of blood supply at all levels. The objective of the present study was to assess the prevalence and trend of transfusion transmitted infections (TTI) among voluntary and replacement donors in the Department of Blood bank and transfusion Medicine of JSS College Hospital, a teaching hospital of Mysore during the period from 2004 to 2008. A retrospective review of donors record covering the period between 2004 and 2008 at the blood bank, JSS Hospital, Mysore was carried out. All samples were screened for HIV, HBsAg, HCV, syphilis and malaria. Of the 39,060, 25,303 (64.78%) were voluntary donors and the remaining 13,757 (35.22%) were replacement donors. The overall prevalence of HIV, HbsAg, HCV and syphilis were 0.44, 1.27, 0.23 and 0.28%, respectively. No blood donor tested showed positivity for malarial parasite. Majority were voluntary donors with male preponderance. In all the markers tested there was increased prevalence of TTI among the replacement donors as compared to voluntary donors. With the implementation of strict donor criteria and use of sensitive screening tests, it may be possible to reduce the incidence of TTI in the Indian scenario.

  14. Use of Radiolabelled Thymidine and Leucine To Estimate Bacterial Production in Soils from Continental Antarctica

    PubMed Central

    Tibbles, B. J.; Harris, J. M.

    1996-01-01

    Tritiated thymidine incorporation (TTI) into DNA was used to examine bacterial production in two soil types from the Robertskollen group of nunataks in northwestern Dronning Maud Land, providing the first estimates of bacterial production in soil habitats on the Antarctic continent. Although estimates of bacterial productivity in soils near to bird nests (344 (plusmn) 422 ng of C g [dry weight](sup-1) h(sup-1)) were higher than those for soils from beneath mosses (175 (plusmn) 90 ng of C g [dry weight](sup-1) h(sup-1); measured by TTI at 10(deg)C), these differences were not significant because of patchiness of bacterial activity (P > 0.05). TTI- and [(sup14)C]leucine ([(sup14)C]Leu)-derived estimates of bacterial production were similar when incubations of 3 h were used, although incubations as short as 1 h were sufficient for measurable uptake of radiolabel. Dual-label incorporation of [(sup3)H]thymidine ([(sup3)H]TdR) into DNA and [(sup14)C]Leu into protein indicated that TTI did not reflect bacterial production of in situ assemblages when incubations were longer than 3 h. Isotope dilution analysis indicated that dilution of the specific activity of exogenously supplied [(sup3)H]TdR by de novo synthesis of TdR precursor could be limited by additions of [(sup3)H]TdR at a concentration of 1 nmol per ca. 115 mg of soil. TTI exhibited a psychrotrophic response to variation in temperature, with a temperature optimum of ca. 15(deg)C and a Q(inf10) value for 0 to 10(deg)C of 2.41. PMID:16535246

  15. Skeletal muscle is sensitive to the tension-time integral but not to the rate of change of tension, as assessed by mechanically induced signaling.

    PubMed

    Martineau, Louis C; Gardiner, Phillip F

    2002-05-01

    Mechanical forces regulate many cellular processes. Mechanotransduction, however, is poorly understood. In skeletal muscle, mechanical forces have a major impact on the regulation of cellular volume, yet the nature of the mechanical stimulation to which muscle is most sensitive is unknown. It was recently demonstrated that activation of the mechanically-sensitive kinase p54 jun-N-terminal-kinase (JNK), is a quantitative marker of mechanical stimulation in skeletal muscle. This marker was shown to be more sensitive to peak tension than to other tension-related parameters such as the tension-time integral (TTI) and the rate of change of tension (dT/dt). The purpose of the present study was to parcel out the contribution of TTI and dT/dt to mechanical stimulation of muscle under conditions of constant peak tension. The rat medial gastrocnemius in situ was subjected to one of four 5-min passive stretch protocols consisting of equal length excursions, but differing in displacement-time integral (4%, 40%, or 100%) and/or rate of stretch (0, 3, or 30 mm/s), and the resulting p54-JNK phosphorylation was assessed. A linear relationship between TTI and p54-JNK signaling was observed. However, no effect of dT/dt was observed. It is concluded that peak tension and TTI are necessary parameters for modeling the mechanical stimulus-response of muscle. Additionally, the mechanism of mechanotransduction is sensitive to peak tension and TTI, but not to dT/dt, and thus exhibits spring-like behavior. These findings may contribute to the refinement of disuse atrophy countermeasures.

  16. Physical dilatation of the nostrils lowers the thermal strain of exercising humans.

    PubMed

    White, M D; Cabanac, M

    1995-01-01

    Increased nasal air flow during exercise was examined as a possible heat loss avenue contributing to selective brain cooling in hyperthermic humans. On 2 separate days, eight subjects [mean (SE) age, 26.4 (1.2) years] exercised on a cycle ergometer in a warm room [28 (0.2) degrees C; 28 (5)% relative humidity] to induce a moderate level of hyperthermia. In one session the nostrils were physically dilatated [average dilatation 1.55 (0.17) times] and in the other they were not (control). Both sessions started with a 5-min resting period; then subjects pedaled at 60 W for 5 min, 100 W for 15 min, and 150 W for 20 min. During dilatation both tympanic temperature (Tty) and forehead skin blood flow, estimated by laser doppler velocimetry, were significantly lower than during the control exercise of 150 W. Rates of increase of Tty during the 100-W exercise were the same in both conditions; however, during the 150-W exercise with dilatated nostrils Tty increased at a rate significantly lower than during control [1.1 (0.3) degrees C.h-1 vs 1.5 (0.4) degrees C.h-1]. The change in the rate of increase of Tty between conditions was significantly correlated to the degree of nostril dilatation (r = -0.77, P = 0.02), suggesting that the lower Tty observed was due to nostril dilatation. Facial skin temperature was not significantly different between sessions. The results suggest that the nasal cavity may act as a heat exchanger in selective brain cooling of exercising humans.

  17. Neuromuscular fatigue following isometric contractions with similar torque time integral.

    PubMed

    Rozand, V; Cattagni, T; Theurel, J; Martin, A; Lepers, R

    2015-01-01

    Torque time integral (TTI) is the combination of intensity and duration of a contraction. The aim of this study was to compare neuromuscular alterations following different isometric sub-maximal contractions of the knee extensor muscles but with similar TTI. Sixteen participants performed 3 sustained contractions at different intensities (25%, 50%, and 75% of Maximal Voluntary Contraction (MVC) torque) with different durations (68.5±33.4 s, 35.1±16.8 s and 24.8±12.9 s, respectively) but similar TTI value. MVC torque, maximal voluntary activation level (VAL), M-wave characteristics and potentiated doublet amplitude were assessed before and immediately after the sustained contractions. EMG activity of the vastus lateralis (VL) and -rectus femoris (RF) muscles was recorded during the sustained contractions. MVC torque reduction was similar in the 3 conditions after the exercise (-23.4±2.7%). VAL decreased significantly in a similar extent (-3.1±1.3%) after the 3 sustained contractions. Potentiated doublet amplitude was similarly reduced in the 3 conditions (-19.7±1.5%), but VL and RF M-wave amplitudes remained unchanged. EMG activity of VL and RF muscles increased in the same extent during the 3 contractions (VL: 54.5±40.4%; RF: 53.1±48.7%). These results suggest that central and peripheral alterations accounting for muscle fatigue are similar following isometric contractions with similar TTI. TTI should be considered in the exploration of muscle fatigue during sustained isometric contractions.

  18. Development, Testing, and Application of a Coupled Hydrodynamic Surface-Water/Groundwater Model (FTLOADDS) with Heat and Salinity Transport in the Ten Thousand Islands/Picayune Strand Restoration Project Area, Florida

    USGS Publications Warehouse

    Swain, Eric D.; Decker, Jeremy D.

    2009-01-01

    A numerical model application was developed for the coastal area inland of the Ten Thousand Islands (TTI) in southwestern Florida using the Flow and Transport in a Linked Overland/Aquifer Density-Dependent System (FTLOADDS) model. This model couples a two-dimensional dynamic surface-water model with a three-dimensional groundwater model, and has been applied to several locations in southern Florida. The model application solves equations for salt transport in groundwater and surface water, and also simulates surface-water temperature using a newly enhanced heat transport algorithm. One of the purposes of the TTI application is to simulate hydrologic factors that relate to habitat suitability for the West Indian Manatee. Both salinity and temperature have been shown to be important factors for manatee survival. The inland area of the TTI domain is the location of the Picayune Strand Restoration Project, which is designed to restore predevelopment hydrology through the filling and plugging of canals, construction of spreader channels, and the construction of levees and pump stations. The effects of these changes are simulated to determine their effects on manatee habitat. The TTI application utilizes a large amount of input data for both surface-water and groundwater flow simulations. These data include topography, frictional resistance, atmospheric data including rainfall and air temperature, aquifer properties, and boundary conditions for tidal levels, inflows, groundwater heads, and salinities. Calibration was achieved by adjusting the parameters having the largest uncertainty: surface-water inflows, the surface-water transport dispersion coefficient, and evapotranspiration. A sensitivity analysis did not indicate that further parameter changes would yield an overall improvement in simulation results. The agreement between field data from GPS-tracked manatees and TTI application results demonstrates that the model can predict the salinity and temperature

  19. Use of smart photochromic indicator for dynamic monitoring of the shelf life of chilled chicken based products.

    PubMed

    Brizio, Ana Paula Dutra Resem; Prentice, Carlos

    2014-03-01

    This study evaluated the applicability of a photochromic time temperature indicator (TTI) to monitor the time-temperature history and shelf life of chilled boneless chicken breast. The results showed that the smart indicator showed good reproducibility during the discoloring process in all the conditions investigated. The response was not only visibly interpretable but also well adaptable to measurement using appropriate equipment. For an activation configuration of 4 s of ultraviolet light (UV) per label, the TTI's rate of discoloration was similar to the quality loss of the meat samples analyzed. Thus, the photochromic label (4 s UV/label) attached to the samples set out to be a dynamic shelf-life label, assuring consumers the final point of quality of chilled boneless chicken breast in an easy and precise form, providing a reliable tool to monitor the supply chain of this product.

  20. Time-to-impact sensors in robot vision applications based on the near-sensor image processing concept

    NASA Astrophysics Data System (ADS)

    Åström, Anders; Forchheimer, Robert

    2012-03-01

    Based on the Near-Sensor Image Processing (NSIP) concept and recent results concerning optical flow and Time-to- Impact (TTI) computation with this architecture, we show how these results can be used and extended for robot vision applications. The first case involves estimation of the tilt of an approaching planar surface. The second case concerns the use of two NSIP cameras to estimate absolute distance and speed similar to a stereo-matching system but without the need to do image correlations. Going back to a one-camera system, the third case deals with the problem to estimate the shape of the approaching surface. It is shown that the previously developed TTI method not only gives a very compact solution with respect to hardware complexity, but also surprisingly high performance.

  1. Transfusion-transmitted infections among multitransfused patients in Iran: a review.

    PubMed

    Rezvan, H; Abolghassemi, H; Kafiabad, S Amini

    2007-12-01

    Transfusion-transmitted infections (TTI) continue to be a major challenge for Blood transfusion organizations across the world. The problem is more serious in the developing countries with lower economic means. Multitransfused patients (MTPs) in these countries are at higher risk of infection, and studies of infection in these patients can be a useful index for examining the blood safety filters in place. The present article reviews the situation in Iran, where prevalence of the major viruses of concern, namely, hepatitis B virus, hepatitis C virus (HCV) and human immunodeficiency virus, studied in these patients is reported over a 9-year period. It is demonstrated that HCV is the most prevalent TTI and remains a major health problem for these patients.

  2. Epidemiology of Transfusion-Transmitted Infections Among Multi-Transfused Patients in Seven Hospitals in Peru

    DTIC Science & Technology

    2005-01-01

    Prevalence and risk factors vary by geographic location and by the specific TTI (including HIV-1, HBV, HCV and HTLV -I) Objective To determine the prevalence... HTLV -I infection HIV infection was associated only with total number of traxlsfuslon units received Conclusions High prevalences of HBV and HCV...Multi-transfused, HIV-1, HBV, HCV, HTLV -I, Epldemmlogy 1. Introduction The worldwide dlstnbunon of hepanns C wrus (HCV) mfecnon includes 170 mflhon

  3. Emergency Medical Treatment Needs: Chronic and Acute Exposure to Hazardous Materials.

    DTIC Science & Technology

    1982-06-01

    Written-Material Resources Distribution List I I .tti. --1..... INDEX OF FIGURES 1 ~ Page 1 Sample Posting from RTECS Under Category "Moderate - Eye...Irritation 8 INDEX OF TABLES 1 Chemical Classes Listed in Industrial Hygiene and Toxicology 6 2 Categories Used in the RTECS Data Bank 7 3 Matrix of...readily available, unbiased listing of chemicals in order * to correlate medical guidelines with chemical classification groups. The starting point for

  4. Reliability and Maintainability Analysis of Fluidic Back-Up Flight Control System and Components.

    DTIC Science & Technology

    1981-09-01

    being used in various aircraft applications are demonstrating extremely high reliability. However, the unique design of new fluidic compo- nents results...in a very limited failure rate data base and prevents the determination of numerical values of fluidic system reliability at a sufficient confidence...Did. 6601 WWINlTTi’ G.ASUFIOATION OF TH PAGE (116 flm e UAK 80227-60 EXECUTIVE SUMMARY BACKGROUND High reliability in flight control systems is achieved

  5. The Tri-Trophic Interactions Hypothesis: Interactive Effects of Host Plant Quality, Diet Breadth and Natural Enemies on Herbivores

    PubMed Central

    Mooney, Kailen A.; Pratt, Riley T.; Singer, Michael S.

    2012-01-01

    Several influential hypotheses in plant-herbivore and herbivore-predator interactions consider the interactive effects of plant quality, herbivore diet breadth, and predation on herbivore performance. Yet individually and collectively, these hypotheses fail to address the simultaneous influence of all three factors. Here we review existing hypotheses, and propose the tri-trophic interactions (TTI) hypothesis to consolidate and integrate their predictions. The TTI hypothesis predicts that dietary specialist herbivores (as compared to generalists) should escape predators and be competitively dominant due to faster growth rates, and that such differences should be greater on low quality (as compared to high quality) host plants. To provide a preliminary test of these predictions, we conducted an empirical study comparing the effects of plant (Baccharis salicifolia) quality and predators between a specialist (Uroleucon macolai) and a generalist (Aphis gossypii) aphid herbivore. Consistent with predictions, these three factors interactively determine herbivore performance in ways not addressed by existing hypotheses. Compared to the specialist, the generalist was less fecund, competitively inferior, and more sensitive to low plant quality. Correspondingly, predator effects were contingent upon plant quality only for the generalist. Contrary to predictions, predator effects were weaker for the generalist and on low-quality plants, likely due to density-dependent benefits provided to the generalist by mutualist ants. Because the TTI hypothesis predicts the superior performance of specialists, mutualist ants may be critical to A. gossypii persistence under competition from U. macolai. In summary, the integrative nature of the TTI hypothesis offers novel insight into the determinants of plant-herbivore and herbivore-predator interactions and the coexistence of specialist and generalist herbivores. PMID:22509298

  6. International Competitiveness: A National Security Perspective

    DTIC Science & Technology

    1989-06-01

    49 National IndustrialfTechnological Policy ................... 49 Abandoning the "Not-Invented-Here" Syndrome ............... 49 Conclusions...industry h:s cha uuet lratnalically over tlie years,. the US industry. Even though the overall demand for In 19(0 1)OD wa the nl’t.ty’s most...busincss. So while independent spirit and preference for a market-driven the United States cries about unfair practices of the economy. Of course

  7. Ensuring Successful Personnel Management in the Department of Homeland Security

    DTIC Science & Technology

    2002-01-01

    particular, retention allowances, buy- outs, and early retirement incentives can induce federal workers to change their retention, separation, and...voluntary separation incen- tive or “buyout“ program. Buyouts and early retirement incentives helped ease the negative effects on workers whose...t hirnme: Odiffuring tty thatcay i ciduerali aly t hi9byntt abou2 10 percerd. Thl studt alsquesmstated ohe effeers ve early retirement option was

  8. Allied Forces, Mediterranean Theater, Western Task Force Operation Plan Number 4-44, Volume 1

    DTIC Science & Technology

    1944-07-24

    LARNE (SO), CLINTON, OCTAVIA , STORM- CLOUD, WELFARE ... ML 559, 560, 562, 567 KENTYRE (Dan Layer) ’ . . . HACKBERRY, PEPPERWOOD (Additional sweepers...GARLAND, NAVARINON DesRon Seventeen A - DesDiv Thirty. three (less NELSON, GLE-NNON) MURPHY, JEFFERS: : ’ . - DesDiv Thirty-four . BUTLER (F...R,W, 100 Rockets C. CARROLL AtlGUSIft. GLEAVES SOMERS LORRAIHE5 OIKOIH&TTI MARBLEHEAD BUTLER 1 EDY 1 2DY. 2 R.W. Launchers and 200 Rockets 2

  9. Malignant pleural effusions and the role of talc poudrage and talc slurry: a systematic review and meta-analysis

    PubMed Central

    Mummadi, Srinivas; Kumbam, Anusha; Hahn, Peter Y.

    2015-01-01

    Background: Malignant Pleural Effusion (MPE) is common with advanced malignancy. Palliative care with minimal adverse events is the cornerstone of management. Although talc pleurodesis plays an important role in treatment, the best modality of talc application remains controversial.   Objective: To compare rates of successful pleurodesis, rates of respiratory and non-respiratory complications between thoracoscopic talc insufflation/poudrage (TTI) and talc slurry (TS).  Data sources and study selection: MEDLINE (PubMed, OVID),  EBM Reviews (Cochrane database of Systematic Reviews, ACP Journal Club, DARE, Cochrane Central Register of Controlled Trials, Cochrane Methodology Register, Health Technology Assessment and NHS Economic Evaluation Database), EMBASE and Scopus. Randomized controlled trials published between 01/01/1980 - 10/1/2014 and comparing the two strategies were selected.  Results: Twenty-eight potential studies were identified of which 24 studies were further excluded, leaving four studies. No statistically significant difference in the probability of successful pleurodesis was observed between TS and TTI groups (RR 1.06; 95 % CI 0.99-1.14; Q statistic, 4.84). There was a higher risk of post procedural respiratory complications in the TTI group compared to the TS group (RR 1.91, 95% CI= 1.24-2.93, Q statistic 3.15). No statistically significant difference in the incidence of non-respiratory complications between the TTI group and the TS group was observed (RR 0.88, 95% CI= 0.72-1.07, Q statistic 4.61). Conclusions: There is no difference in success rates of pleurodesis based on patient centered outcomes between talc poudrage and talc slurry treatments.  Respiratory complications are more common with talc poudrage via thoracoscopy. PMID:25878773

  10. Risk Factors for Transfusion Transmissible Infections Elicited on Post Donation Counselling in Blood Donors: Need to Strengthen Pre-donation Counselling.

    PubMed

    Sachdev, Suchet; Mittal, Kshitija; Patidar, Gopal; Marwaha, Neelam; Sharma, Ratti Ram; Duseja, Ajay Kumar; Chawla, Yogesh Kumar; Arora, Sunil Kumar

    2015-09-01

    Donor notification and counselling transforms the legal and ethical requirement of disclosure of transfusion transmissible infection (TTI) in a blood donor into practice. The present study was done to assess the response to the disclosure of TTI reactivity results in blood donors, assess the risk factors in blood donors and follow the compliance of the disclosure and clinical referral in a population of blood donors who are difficult to convince that they may be harbouring infections apparently in a healthy state today but with possible clinical disease consequences in the future. A retrospective study was conducted from April 2011 to November 2012. Screening was done using third generation ELISA kits used according to the manufacturer's directions; these kits were approved for use in blood banks by the Drug Controller General of India. Those testing repeat reactive were referred for further confirmation and management. The total number of TTI reactive donors was 787 (0.93 %, N = 83,865). The observed response rate in the present study is 21.6 % (167, N = 787). The risk factors for acquiring infections in TTI reactive donors were statistically significant history of high risk behaviour (20.3 %) for human immunodeficiency virus infection and history of jaundice in themselves, family or close contacts (16.1 %) for hepatitis B virus infection. One hundred and ten (65.8 %) of the referred donors were on outpatient clinical care when post-referral follow up was conducted. The study emphasises on continuing sensitization of blood donation camp organisers to the need of privacy during blood donor selection. The study also stresses the need to strengthen the pre-donation counselling at outdoor blood donation at the same time raise awareness amongst blood donors about the importance of post-donation counselling and follow up.

  11. Is Having Sex with Other Men a Risk Factor for Transfusion-Transmissible Infections in Male Blood Donors in Western Countries? A Systematic Review

    PubMed Central

    De Buck, Emmy; Dieltjens, Tessa; Compernolle, Veerle; Vandekerckhove, Philippe

    2015-01-01

    Background Although increased prevalence of transfusion transmissible infections (TTI) among “men who have sex with men” (MSM) has been well documented, the exclusion of MSM as blood donors is contested. The aim of this systematic review is to find studies that describe the risk of TTI in MSM blood donors. Methods We searched MEDLINE, Embase, The Cochrane Central Register of Controlled Trials, Cinahl, and Web of Science, and used GRADE for determining evidence quality. We included studies comparing MSM and non-MSM blood donors (or people eligible to give blood), living in areas most relevant for our Blood Service. Results Out of 18 987 articles, 14 observational studies were included. Two studies directly compared MSM with non-MSM donors showing that MSM donors have a statistically significant higher risk of HIV-1 infections. In one of these studies it was shown that this was related to recent (< 12 months) MSM contact. In two additional studies no evidence was shown in favour of a certain deferral period for MSM. Ten studies, applying permanent deferral for MSM, compared infected versus non-infected donors. One study found that MSM is a statistically significant risk factor for HIV-1 infection in blood donors. For other TTI such as HBV or HCV, an increased risk of infection could not be demonstrated, because the precision of the results was affected by the low numbers of donors with MSM as risk factor, or because of risk of bias in the included studies. All studies included low level evidence, because of risk of bias and imprecision of the results. Conclusions High-quality studies investigating the risk of TTI in MSM who donate blood are scarce. The available evidence suggests a link between MSM blood donors and HIV-1 infection, but is too limited to be able to unambiguously/clearly recommend a certain deferral policy. PMID:25875812

  12. Superconductivity for Electromagnetic Guns

    DTIC Science & Technology

    1984-03-01

    34Experimental Cryophysics" Ed. F.E, Hoare et al,, (Butterworth, London 1961) 26, R. Barron " Cryogenics Systems " (McGraw Hill, NY 1966) 27, T,R...ICCS rather than ’the size of the disturbed zone. 14 Cryogenics for System Superinsulators An estimate for the power required for the cooling...1 tti#f URGE CALIBER WEAPON SYSTEMS LABORATORY ^SP^ DOVER, NEW JERSEY Approved for public release, distribution unlimited. The views, opinions

  13. TRADOC Union List of Periodicals.

    DTIC Science & Technology

    1988-08-01

    TTG v. 14, 1963+ Combat Forces Journal (continued by Arms Magazine) TSJ Aug 1950-Jjl 1956. Combat Lessons TSQ Vol. 2-5 (Bound). Comercio Exterior...TTY Jul 1985 Comercio -El TSL Current 12 issues only Command Information Package (includes Officers Call, Commanders Notes, Sergeants Business and...Inc). Joint Services Recognition Journal FTE v. 35, 1980+ TTF Feb 1977-1982 ( mnc). TTG v. I, 1946-v. 9, 1954 Jorrial Do Brasil TSL Current 12 issues

  14. Aortic reservoir function, estimated myocardial demand and coronary perfusion pressure following steady-state and interval exercise.

    PubMed

    Lane, A D; Heffernan, K S; Rossow, L M; Fahs, C A; Ranadive, S M; Yan, H; Baynard, T; Wilund, K; Fernhall, B

    2012-09-01

    Aortic reservoir function is a measure of the aorta's ability to distribute blood during diastole, attenuating the pulsatility of blood flow, and is important in balancing cardiac flow. Effects of acute high versus moderate exercise intensity on reservoir function and cardiac energetics is unknown. Eighteen athletes completed a interval (INT) and steady-state (SS) cycling bout at 60% of VO(2) peak. Reservoir function was calculated as the ratio of diastolic run-off to stroke volume and expressed as a percentage. Coronary perfusion pressure was derived from tissue Doppler imaging and echocardiography. Systolic tension-time integral (TTI) from the aortic pressure waveform served as a measure of myocardial oxygen consumption. All measures were made at rest, 30-min postexercise and 60-min postexercise. Average reservoir function before SS was 76%, which was reduced to 62% 30-min post-SS and 67% 60-min post-SS (P<0.05). Significantly greater reductions in reservoir function were seen following INT (from 71% pre-INT to 45% 30-min post-INT and 53% 60-min INT, P<0.05). Estimated coronary perfusion pressure was reduced 30 min following INT but not SS; both bouts reduced coronary perfusion pressure at 60-min postexercise (P<0.05). TTI increased following both INT and SS at 30- and 60-min postexercise with greater increases following INT (P<0.05). Following exercise, reservoir function was associated with TTI (P<0.05), but not coronary perfusion pressure (P>0.05). We conclude that reservoir function is attenuated following acute SS and INT, but these reductions were greater post-INT, suggesting that exercise intensity affects reservoir function. Reduction of reservoir function following exercise is related to TTI, a reflection of myocardial oxygen consumption but apparently not associated with coronary perfusion pressure.

  15. Hybrid Microcircuit Rework Procedures Evaluation.

    DTIC Science & Technology

    1980-08-01

    collect. Careful selection of materials and process control can reduce the work stage tempera- tures to 200°C or less; actual work stage temperatures are...ULTRASONIC DIE BONDELNON-DEST WRUCIV IOD - WIRE BOND CLEAN CURE SEMICONODUCTOR ETICA WIRE BOND V SEMICONDUCTOR SUBSTRATE ADHESIVE CHIPS TO TTI N I CHIPS...data were normalized to reflect the actual number of hybrids produced. The percentages of travelers examined varied from 5 to 50 percent of the total

  16. Use of global sensitivity analysis in quantitative microbial risk assessment: application to the evaluation of a biological time temperature integrator as a quality and safety indicator for cold smoked salmon.

    PubMed

    Ellouze, M; Gauchi, J-P; Augustin, J-C

    2011-06-01

    The aim of this study was to apply a global sensitivity analysis (SA) method in model simplification and to evaluate (eO)®, a biological Time Temperature Integrator (TTI) as a quality and safety indicator for cold smoked salmon (CSS). Models were thus developed to predict the evolutions of Listeria monocytogenes and the indigenous food flora in CSS and to predict TTIs endpoint. A global SA was then applied on the three models to identify the less important factors and simplify the models accordingly. Results showed that the subset of the most important factors of the three models was mainly composed of the durations and temperatures of two chill chain links, out of the control of the manufacturers: the domestic refrigerator and the retail/cabinet links. Then, the simplified versions of the three models were run with 10(4) time temperature profiles representing the variability associated to the microbial behavior, to the TTIs evolution and to the French chill chain characteristics. The results were used to assess the distributions of the microbial contaminations obtained at the TTI endpoint and at the end of the simulated profiles and proved that, in the case of poor storage conditions, the TTI use could reduce the number of unacceptable foods by 50%.

  17. Non-electrical-power temperature-time integrating sensor for RFID based on microfluidics

    NASA Astrophysics Data System (ADS)

    Schneider, Mike; Hoffmann, Martin

    2011-06-01

    The integration of RFID tags into packages offers the opportunity to combine logistic advantages of the technology with monitoring different parameters from inside the package at the same time. An essential demand for enhanced product safety especially in pharmacy or food industry is the monitoring of the time-temperature-integral. Thus, completely passive time-temperature-integrators (TTI) requiring no battery, microprocessor nor data logging devices are developed. TTI representing the sterilization process inside an autoclave system is a demanding challenge: a temperature of at least 120 °C have to be maintained over 45 minutes to assure that no unwanted organism remains. Due to increased temperature, the viscosity of a fluid changes and thus the speed of the fluid inside the channel increases. The filled length of the channel represents the time temperature integral affecting the system. Measurements as well as simulations allow drawing conclusions about the influence of the geometrical parameters of the system and provide the possibility of adaptation. Thus a completely passive sensor element for monitoring an integral parameter with waiving of external electrical power supply and data processing technology is demonstrated. Furthermore, it is shown how to adjust the specific TTI parameters of the sensor to different applications and needs by modifying the geometrical parameters of the system.

  18. Hepatitis B, Hepatitis C, Human immunodeficiency virus and syphilis frequency among blood donors: A single center study.

    PubMed

    Yildiz, Sule Menziletoglu; Candevir, Aslihan; Kibar, Filiz; Karaboga, Gulser; Turhan, Ferda Tekin; Kis, Cem; Dincer, Suleyman; Guvenc, Birol

    2015-12-01

    We aimed to provide updated results for seroprevalence of hepatitis B, hepatitis C viruses while presenting first data for human immunodeficiency virus and syphilis seropositivity amongst blood donors in Adana, Turkey. Screening and confirmatory test results of 62,461 donors were evaluated. HBsAg, anti-HCV, anti-HIV1/2 and syphilis seropositivity was 1.92%, 0.48%, 0.20%, 0.18% respectively, based on screening tests, and 1.66%, 0.05%, 0.003%, 0.10% respectively, according to confirmatory tests. Transfusion-transmitted infections (TTI) was more prevalent in low-educated donors. HBsAg and syphilis seropositivity rates were higher in married subjects. We found that the prevalence of HBV and HCV was significantly decreased in the last two decades in Adana. Importantly, this study provides first data in HIV and syphilis seropositivity rates among blood donors in our region and both HIV and syphilis seroprevalences were found to be low compared to many regions of Turkey. However, considering the fact that increasing number of immigrants may change prevalences and trends of TTI both in Adana and in Turkey, strict monitorization and yearly reporting of TTI rates seem necessary to be able to take proactive measures.

  19. Stylet angulation for routine endotracheal intubation with McGrath videolaryngoscope

    PubMed Central

    Lee, Jiyoung; Kim, Jong Yeop; Kang, Se Yoon; Kwak, Hyun Jeong; Lee, Dongchul; Lee, Sook Young

    2017-01-01

    Abstract Background: The McGrath videolaryngoscope (VL) provides excellent laryngoscopic views, but directing an endotracheal tube can be difficult, and thus the routine use of a stylet is recommended. The goal of this study is to determine the appropriate angle (60° vs 90°) of the stylet when using the McGrath VL by comparing the time to intubation (TTI). Methods: One hundred and forty patients aged 19 to 70 years (American Society of Anesthesiologists classification I or II) who required tracheal intubation for elective surgery were randomly allocated to 1 of 2 groups, at the 60° angle (n = 70) or the 90° angle (n = 70). Anesthesia was induced with propofol, fentanyl, and rocuronium. The primary outcome was TTI assessed by a blind observer. Glottic grade, use of optimal external laryngeal manipulation, failed intubation at first attempt, ease of intubation, and severity of oropharyngeal bleeding were also recorded. Results: The mean TTI was significantly shorter in the 60° group than in the 90° group (29.3 ± 6.4 vs 32.5 ± 9.4 s, P = 0.022). The glottic grade and degree of intubation difficulty were not significantly different between the 2 groups. Conclusions: When intubating the patients with the McGrath videolaryngoscope, the 60° angled stylet allowed for faster orotracheal intubation than did the 90° angled stylet. PMID:28207549

  20. Effects of whole-body cryotherapy (-110 °C) on proprioception and indices of muscle damage.

    PubMed

    Costello, J T; Algar, L A; Donnelly, A E

    2012-04-01

    The purpose of this study was to investigate the effects of whole-body cryotherapy (WBC) on proprioceptive function, muscle force recovery following eccentric muscle contractions and tympanic temperature (T(TY) ). Thirty-six subjects were randomly assigned to a group receiving two 3-min treatments of -110 ± 3 °C or 15 ± 3 °C. Knee joint position sense (JPS), maximal voluntary isometric contraction (MVIC) of the knee extensors, force proprioception and T(TY) were recorded before, immediately after the exposure and again 15 min later. A convenience sample of 18 subjects also underwent an eccentric exercise protocol on their contralateral left leg 24 h before exposure. MVIC (left knee), peak power output (PPO) during a repeated sprint on a cycle ergometer and muscles soreness were measured pre-, 24, 48 and 72h post-treatment. WBC reduced T(TY) , by 0.3 °C, when compared with the control group (P<0.001). However, JPS, MVIC or force proprioception was not affected. Similarly, WBC did not effect MVIC, PPO or muscle soreness following eccentric exercise. WBC, administered 24 h after eccentric exercise, is ineffective in alleviating muscle soreness or enhancing muscle force recovery. The results of this study also indicate no increased risk of proprioceptive-related injury following WBC.

  1. Long-term effects of tetanus toxoid inoculation on the demography and life expectancy of the Cayo Santiago rhesus macaques.

    PubMed

    Kessler, Matthew J; Hernández Pacheco, Raisa; Rawlins, Richard G; Ruiz-Lambrides, Angelina; Delgado, Diana L; Sabat, Alberto M

    2015-02-01

    Tetanus was a major cause of mortality in the free-ranging population of rhesus monkeys on Cayo Santiago prior to 1985 when the entire colony was given its first dose of tetanus toxoid. The immediate reduction in mortality that followed tetanus toxoid inoculation (TTI) has been documented, but the long-term demographic effects of eliminating tetanus infections have not. This study uses the Cayo Santiago demographic database to construct comparative life tables 12 years before, and 12 years after, TTI. Life tables and matrix projection models are used to test for differences in: (i) survival among all individuals as well as among social groups, (ii) long-term fitness of the population, (iii) age distribution, (iv) reproductive value, and (v) life expectancy. A retrospective life table response experiment (LTRE) was performed to determine which life cycle transition contributed most to observed changes in long-term fitness of the population post-TTI. Elimination of clinical tetanus infections through mass inoculation improved the health and well-being of the monkeys. It also profoundly affected the population by increasing survivorship and long-term fitness, decreasing the differences in survival rates among social groups, shifting the population's age distribution towards older individuals, and increasing reproductive value and life expectancy. These findings are significant because they demonstrate the long-term effects of eradicating a major cause of mortality at a single point in time on survival, reproduction, and overall demography of a naturalistic population of primates.

  2. Seasonal and Spatial Distribution of Freshwater Flow and Salinity in the Ten Thousand Islands Estuary, Florida, 2007-2009

    USGS Publications Warehouse

    Soderqvist, Lars E.; Patino, Eduardo

    2010-01-01

    The watershed of the Ten Thousand Islands (TTI) estuary has been substantially altered through the construction of canals and roads for the Southern Golden Gate Estates (SGGE), Barron River Canal, and U.S. 41 (Tamiami Trail). Two restoration projects designed to improve freshwater delivery to the estuary are the Picayune Strand Restoration Project, which includes the Southern Golden Gate Estates, and the Tamiami Trail Culverts Project; both are part of the Comprehensive Everglades Restoration Plan. To address hydrologic information needs critical for monitoring the effects of these restoration projects, the U.S. Geological Survey initiated a study in October 2006 to characterize freshwater outflows from the rivers, internal circulation and mixing within the estuary, and surface-water exchange between the estuary and Gulf of Mexico. The effort is conducted in cooperation with the South Florida Water Management District and complemented by monitoring performed by the Rookery Bay National Estuarine Research Reserve. Surface salinity was measured during moving boat surveys using a flow-through system that operated at planing speeds averaging 20 miles per hour. The data were logged every 10 seconds by a data recorder that simultaneously logged location information from a Global Positioning System. The major rivers, bays, and nearshore Gulf of Mexico region of the TTI area were surveyed in approximately 5 hours by two boats traversing about 200 total miles. Salinity and coordinate data were processed using inverse distance weighted interpolation to create salinity contour maps of the entire TTI region. Ten maps were created from salinity surveys performed between May 2007 and May 2009 and illustrate the dry season, transitional, and wet season salinity patterns of the estuarine rivers, inner bays, mangrove islands, and Gulf of Mexico boundary. The effects of anthropogenic activities are indicated by exceptionally low salinities associated with point discharge into the

  3. An Analysis of and Recommendations for the Peruvian Blood Collection and Transfusion System

    PubMed Central

    George, Paul E; Vidal, Julio; Garcia, Patricia J

    2016-01-01

    Background Peru experienced a crisis in its blood collection and supply system in the mid-2000s, as contaminated blood led to several transfusion-transmitted infections (TTI), occurring in the backdrop of extremely low voluntary donation rates and a national blood supply shortage. Thus, the Peruvian Ministry of Health (MINSA) implemented a national investigation on the safety and quality of the Peruvian blood collection/transfusion network. Methods Every Peruvian blood bank was evaluated by MINSA from 2007–2008. These evaluations consisted of an update of the national registry of blood banks and visits to each blood bank from MINSA oversight teams. Information was collected on the condition of the blood bank personnel, equipment, supplies, and practices. Further, previously-collected blood at each blood bank was randomly selected and screened for TTI-causing pathogens. Results Uncovered in this investigation was a fragmented, under-equipped, and poorly-staffed blood collection and transfusion network, consisting of 241 independent blood banks and resulting in suboptimal allocation of resources. Further, blood with evidence of TTI-causing pathogens (including Hepatitis B, Hepatitis C, and syphilis) and set for transfusion was discovered at three separate blood banks as part of the random screening process. Conclusion Using the successful reorganizations of national blood supply systems in other Latin American countries as examples, Peru would be well-served to form large, high-volume, regional blood collection and transfusion centers, responsible for blood collection and screening for the entire country. The small, separate blood banks would then be transformed into a network of blood transfusion centers, not responsible for blood collection. This reorganization would allow Peru to better utilize its resources, standardize the blood collection and transfusion process, and increase voluntary donation, resulting in a safer, more abundant national blood product. PMID

  4. Failure of self-disclosure of deferrable risk behaviors associated with transfusion-transmissible infections in blood donors

    PubMed Central

    Wong, Horas Tze Hoo; Lee, Shui Shan; Lee, Cheuk-Kwong; Chan, Denise Pui Chung

    2015-01-01

    BACKGROUND To date, most studies on deferral of blood donors have focused on men who have sex with men (MSM) and/or injecting drug users. Few have examined deferrable risk behaviors relating to transfusion-transmissible infections (TTIs) in general. This study aimed to examine the prevalence of, and factors associated with, nondisclosure of TTI-related risk behaviors in donors. STUDY DESIGN AND METHODS Chinese-speaking donors who had just given blood in Hong Kong were invited to self-complete an anonymous questionnaire. Practices of one or more of seven deferrable risk behaviors associated with TTI were inquired. Factors associated with noncompliance with self-disclosure were evaluated by logistic regression. RESULTS Over a 4-week study period in 2012, a total of 1143 donors were recruited. Overall, 0.2% gave a history of drug injection, 1.7% had had sex with sex worker(s), and 0.3% had had sex with a human immunodeficiency virus–infected partner, while none had been paid for sex. Some 1.5% of male donors reported having same-sex behaviors. Factors associated with noncompliance were male gender (odds ratio [OR] 31.1; 95% confidence interval [CI], 3.7-263.6), having multiple sex partners (OR, 89.7; 95% CI, 28.7-279.9), and previous history of temporary deferral (OR, 11.4; 95% CI, 2.5-53.3). If suspected noncompliance was included, the overall prevalence of nondisclosure of deferrable behaviors could be high at 6.5%. CONCLUSION Albeit uncommon, some donors fail to provide accurate answers to predonation screening questions and are not deferred appropriately. There is room for improvement to make deferral policy acceptable and understandable, so as to minimize the risk of TTI. Efforts are also needed to tackle the paucity of data on noncompliance of non-MSM donors. PMID:25846739

  5. The tension-time index and the frequency/tidal volume ratio are the major pathophysiologic determinants of weaning failure and success.

    PubMed

    Vassilakopoulos, T; Zakynthinos, S; Roussos, C

    1998-08-01

    We have previously shown (Am. J. Respir. Crit. Care Med. 1995;152:1248-1255) that in patients needing mechanical ventilation, the load imposed on the inspiratory muscles is excessive relative to their neuromuscular capacity. We have therefore hypothesized that weaning failure may occur because at the time of the trial of spontaneous breathing there is insufficient reduction of the inspiratory load. We therefore prospectively studied patients who initially had failed to wean from mechanical ventilation (F) but had successful weaning (S) on a later occasion. Compared with S, during F patients had greater intrinsic positive end-expiratory pressure (6. 10 +/- 2.45 versus 3.83 +/- 2.69 cm H2O), dynamic hyperinflation (327 +/- 180 versus 213 +/- 175 ml), total resistance (Rmax, 14.14 +/- 4.95 versus 11.19 +/- 4.01 cm H2O/L/s), ratio of mean to maximum inspiratory pressure (0.46 +/- 0.1 versus 0.31 +/- 0.08), tension time index (TTI, 0.162 +/- 0.032 versus 0.102 +/- 0.023) and power (315 +/- 153 versus 215 +/- 75 cm H2O x L/min), less maximum inspiratory pressure (42.3 +/- 12.7 versus 53.8 +/- 15.1 cm H2O), and a breathing pattern that was more rapid and shallow (ratio of frequency to tidal volume, f/VT 98 +/- 38 versus 62 +/- 21 breaths/min/L). To clarify on pathophysiologic grounds what determines inability to wean from mechanical ventilation, we performed multiple logistic regression analysis with the weaning outcome as the dependent variable. The TTI and the f/VT ratio were the only significant variables in the model. We conclude that the TTI and the f/VT are the major pathophysiologic determinants underlying the transition from weaning failure to weaning success.

  6. Engineering and management experience at Texas A&M Transportation Institute

    NASA Astrophysics Data System (ADS)

    Chowdhury, Arif Tahjibul

    This manuscript presents the author's engineering and management experience during his internship in the Materials and Pavements (M&P) Division at the Texas A&M Transportation Institute (TTI), and is a record of study for the Doctor of Engineering at Texas A&M University. Through this internship, he met his established internship objectives of gaining technical knowledge as well as knowledge and skills in project management, organizational communication, and quality management of pavement condition data, and of attaining professional development. In meeting these objectives, the author describes the history, mission, and organizational structure of his workplace. He also presents his experience of developing and delivering a two-week training course on pavement design and construction in Kosovo. Participating in a number of professional development training courses and other activities prepared him for working as an engineering manager. These activities include Delta-T leadership training, an instructor development course, a time management and organizational skills course, and the M&P Division lecture series. Leadership and skills learned through the Delta-T program were beneficial for the employee as well as the employer. For the class project, the author and his teammates performed a study dealing with improving TTI's deliverables. The Delta-T team composed a report summarizing their efforts of examining the current state of TTI's project deliverables, the deliverables' shortcomings, and potential enhancements to expand the deliverables' appeal to additional types of potential users outside the traditional research community. The team also developed a prototype web-based model of deliverables and presented some implementation recommendations. Participating in the Texas Department of Transportation's (TxDOT's) pavement surface distress data collection program enabled the author to become familiar with pavement distress data quality management and thus attain the

  7. Timing of compaction and quartz cementation from integrated petrographic and burial-history analyses, Lower Cretaceous Fall River Formation, Wyoming and South Dakota

    SciTech Connect

    Dutton, S.P.

    1997-01-01

    Integrated petrographic and burial-history studies of Fall River sandstones from outcrop and the subsurface provide insight into the timing of compaction and quartz cementation, the two main porosity-reducing processes in quartzose sandstones. Petrographic study of 95 thin sections of Fall River fluvial valley-fill sandstones from outcrop, Donkey Creek field at 2 km burial depth, and Buck Draw field at 3.8 km indicates that reservoir quality differs significantly in these three areas. Fall River sandstones at the surface contain an average of 31% intergranular volume (IGV) and 2% quartz cement. In both Donkey Creek and Buck Draw fields, the sandstones average 22% IGV, but quartz-cement volume averages 8% in the shallower field and 12% in the deeper. Geometric mean permeability at the surface is 4,700 md, compared with 42 md at 2 km and 2 md at 3.8 km. Burial history of the Fall River sandstone differs greatly in the three areas. The outcropping sandstones were buried to 2 km and had reached 80 C by the end of the Cretaceous. They were then uplifted and have remained at near-surface temperatures since the Paleocene; the calculated time-temperature index (TTI) of these sandstones is 1. Fall River sandstones at Donkey Creek were also buried to 2 km and had reached 80 C by the end of the Cretaceous but remained at that depth during the Tertiary; TTI is 14. In Buck Draw field, Fall River sandstones were buried to 2.5 km during the Cretaceous and then continued to subside during the Tertiary, reaching depths of 4 km and temperatures of 140 C; TTI is 512.

  8. Human skeletal muscle metabolic economy in vivo: effects of contraction intensity, age, and mobility impairment.

    PubMed

    Christie, Anita D; Tonson, Anne; Larsen, Ryan G; DeBlois, Jacob P; Kent, Jane A

    2014-11-01

    We tested the hypothesis that older muscle has greater metabolic economy (ME) in vivo than young, in a manner dependent, in part, on contraction intensity. Twenty young (Y; 24±1 yr, 10 women), 18 older healthy (O; 73±2, 9 women) and 9 older individuals with mild-to-moderate mobility impairment (OI; 74±1, 7 women) received stimulated twitches (2 Hz, 3 min) and performed nonfatiguing voluntary (20, 50, and 100% maximal; 12 s each) isometric dorsiflexion contractions. Torque-time integrals (TTI; Nm·s) were calculated and expressed relative to maximal fat-free muscle cross-sectional area (cm2), and torque variability during voluntary contractions was calculated as the coefficient of variation. Total ATP cost of contraction (mM) was determined from flux through the creatine kinase reaction, nonoxidative glycolysis and oxidative phosphorylation, and used to calculate ME (Nm·s·cm(-2)·mM ATP(-1)). While twitch torque relaxation was slower in O and OI compared with Y (P≤0.001), twitch TTI, ATP cost, and economy were similar across groups (P≥0.15), indicating comparable intrinsic muscle economy during electrically induced isometric contractions in vivo. During voluntary contractions, normalized TTI and total ATP cost did not differ significantly across groups (P≥0.20). However, ME was lower in OI than Y or O at 20% and 50% MVC (P≤0.02), and torque variability was greater in OI than Y or O at 20% MVC (P≤0.05). These results refute the hypothesis of greater muscle ME in old age, and provide support for lower ME in impaired older adults as a potential mechanism or consequence of age-related reductions in functional mobility.

  9. Environmental Pollution: Noise Pollution - Sonic Boom

    DTIC Science & Technology

    1977-06-01

    PREDICTED BY THE THEORY WHICH ACCOUNTS ONLY FOR VQLUHi" EFF-(CTSa T"r’I’•E 1S THUS A SUV•CS!I.0N THAT LIFT EFFECTS ON SONIC-aOOM INTEN IlY MAY 6L...5TAT15TICAL ANALYa.S, uAMA4 MS•SE$HMltNTI LOADS(FORCES)o INTEN5ITY, REFLECTIONs PRS•SURFt MATHEMATICAL PREDICTION * STRUCTURES, RESONANT FRLWUENCYs DAMPING...CONSeRVATIVLLY SUMMARILES THE RESULTS IN A QAMAGE PREDICTION TAOLE AND CHART. INSURANCI ADJUSTLAS ARE 4I•EN GUIUANCt ON TtiE TREATMENT OF SONIC BOOM

  10. Novel Resuscitation from Lethal Hemorrhage Suspended Animation for Delayed Resuscitation

    DTIC Science & Technology

    2005-10-01

    maintained in VF for a of its simplicity. Only one pump was needed. total of 40 mins. Lidocaine (1-1.5 mg/kg in-The experimental protocol was approved by...surroundings, withdraws to pain ); 4, coma RESULTS tion. By protocol, Tty should be approximately (some reflexes or pathologic movements, but 34°C at this time...point. Epinephrine 5 p.g/kg no response to pain ); and 5, death (13-16, 20). Three of the 27 dogs were excluded was administered intravenously before

  11. The Possible Impact of Vessel Wakes on Bank Erosion.

    DTIC Science & Technology

    1979-12-01

    water , the materials forming the bank, and the groundwater may increase the soil’s erodibil1tty by formerly noneroding water currents, wind waves, 6r...Effect of Clay Soil’s Water Content (9) Effect of Clay Soil’s Pore Water Chemistry (10) Effect of Eroding Fluid on Clay Soil (11) Causes of Fluid Changes...Slope Stability Charts 37. b. Factors Affecting Bank Stability 38. i (l), Si•te Geology (2)’ Man-made Structures (3) Changes in Water Content 3

  12. Factors Influencing Army Maintenance

    DTIC Science & Technology

    1989-01-01

    ARI Research Note 89-11 (N 00 Factors Influencing Army Maintenance LOloD Debra C. Evans and J. Thomas Roth Applied Science Associates, Inc. for...1.2.7 .2.7.C.1 11. TITLE (Include Security ClassifIcarIon) Factors Influencing Army Maintenance i2. FERSONAL AuTtiOR(S) Evans, Debra C., and Roth, J...y • ’ Factors and variables that influence maintenance for systems and related manpower, per- sonnel, and training (MPT) characteristics were

  13. Recreation Carrying Capacity Handbook Methods and Techniques for Planning, Design, and Management.

    DTIC Science & Technology

    1980-07-01

    atio R-./ PArw nupri,.t tti :1- -. , * CO .&,*.p, o- 3980... . .. Lannannounce. r ua, r l a , ; d s r t i o l i it B y - D T-I CO I a ~~ ~ ~ ~ ~ vi ,:i...number of recreational units per known for each situation. acre. =-26 If thr4sadfeenebtenr- Hoeetelvl fuesol o THE CO CP FCRYN oread oilcpctete’xee h...observed condition for each "Travel Time," the variance value pre factor in Figure 2b. for ">30 min" is used. Ob-red Eff-et are; F~ co ~s ConditIon Ob

  14. Epidemoligic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides: Baseline Questionnaires

    DTIC Science & Technology

    1982-11-01

    1IF "YES" TO ANY COLUMN HEADING. ASK Q.42b-h FOR THAT COLUMNI _ _._ __ C. Skin that was extra Patches Easier bruising of the akin sensitive or seemed to... yout mI tory experience occupational experience, family history, heal tti hitory and hwa th car# util Ation, Since the interview may take one or two...HEADINC)? I’F "YES" TO ANY COLUMN HEADI.NG ASK p.35b-h FOR THAT COLUMN) A. B. C. Skin that was extra Patches Easier bruising of the skin sensitive or seemed

  15. Image Transmission via Spread Spectrum Techniques

    DTIC Science & Technology

    1978-01-01

    Language Summary, Frame-Store Memory Exe- cutive Program, Derivation of the Fact Cosine Transform, Human Factors Involved With Viewing Compressed...FAST COSINE TRANSFORM. . . 125 APPENDIX E: STUDY OF HUMAN FACTORS INVOLVED WITH VIEWING COMPRESSED IMAGES FROM REMOTE PILOTED VEHICLES...X2n n=0,l,...;N/2-l sn+N/2~XN-l-2n N =N/2, ...,N-1 126 m ttiX ,^ae**£*^^ ^p» *m APPENDIX E STUDY OF HUMAN FACTORS INVOLVED WITH VIEWING

  16. LSI computer design - SUMC/DV.

    NASA Technical Reports Server (NTRS)

    Clapp, W. A.

    1972-01-01

    Advanced Technology Laboratories has designed, built, and tested the first CMOS general-purpose computer. The computer executes 32 instructions that are operation-code compatible with the IBM 360 and RCA Spectra 70 series of computers. The computer is supported by 2k words of main-memory LSI storage and a TTY peripheral for input and output operations. Additionally, a simulator, an assembler, and a loader have been constructed to provide software support to the hardware. This paper provides an overall picture of this computer project.

  17. On-Line Arithmetic Algorithms and Structures for VLSI

    DTIC Science & Technology

    1988-11-01

    oe.Cneqe y h nuew rp, ofc noe in the G - graph , is smallrpthn the number of nodes in the graph used as input to this transformation. 3. Map G-nodes to a...Linear array array PE PE I 1nTTI7IF r1rL 1 1e 32L I e I 2 sal Z.s set 41 4 9 1 1 101LJI~2I~ _Z___________________ Figure 3: Mapping G - graph into linear...undesirable properties for implementation, we do not need to perform step 1 in the procedure above. To obtain the G - graph as indicated in step 2, we

  18. Stability Enhancement of a Flexible Robot Manipulator.

    DTIC Science & Technology

    1983-06-24

    ADC12 - TECMAR DRIVER PAGE 1 APPENDIX F 108 USERLIB.DOC 5-2-83 C $CROUT,$MSG,$CO - TTY 10 ROUTINES C $CA,$DA,$M9,$Tl - FROM FORTN. LIBRARY C C...COUPLERS (LOGICAL) EXTERNALS NONE ADC12 - .....--- DRIVER FOR TECMAR 121BIT A/D CALL SEQ CALL ADC12 (LCHAN,IDATA) ARGUMENTS LCHAN - CHANNEL NUMBER BETWEEN 0...CROMINCROMCO,ADCOS,DACO *USERLIB= ADC12 ,DAC12,DDCIN,DDCOUT,MULLINMULOUT *USERLIB=PRNTHX,FNMOUT,FCI,FCO,NMOUT,MSGCROUT *USERLIB=CNVBN,PRVAL,CICO ; */E NOTE

  19. A Review of Rate Coefficients in the H2-F2 Chemical Laser System

    DTIC Science & Technology

    1976-04-15

    JO, II dHlotonl Horn o’«po>i; II. SUPPLEMENTARY NOTES IV KEY WORDS (Contlnuo on fvorio au# // n»(»mry and td »r>’tty jy block...predicted relaxation rates for HCl, HBr , and HI that substantially agree with experimental data above 700 K. Applying the same theory to HF-HF and DF...contributions indicr* td by varying n is a refined perturbation on the total disappearance rate; therefore, »hc values for k1/w . ... are subject

  20. Primary Adhesively Bonded Structure Technology (PABST). General Material Property Data

    DTIC Science & Technology

    1978-09-01

    RT . FTMS refers to federal Test Methods Standards ijjOTLS: 1 . Salt Spray Corrosion - Panels were diagonally...C I l 190 ■^B*s. m.’ m&mpmmvwmm sv«W*^"i^»l«**™f^’,#’** rt ^’’’*^^.-^’>,:’>. ■ ,-/. . « Säi£ny Specimen 60 x 10 x 1 mm Courtesy Fokker-VFW...4-.L. -U-^-t—. rt .!_ J—f. 1 H 1 1 r—!• I i H-Tti [ f 1 1 " 4- l L- ~-i—• 4-4- -i 1 - 186

  1. Cleavage/Repair and Signal Transduction Pathways in Irradiated Breast Tumor Cells

    DTIC Science & Technology

    2000-09-01

    P, Levade T, Bettaieb A, Andrieu N, Bezombes 75. Leung LK, Wang TTY: Differential effects of chemothera- C, Maestre N, Vermeersch S, Rousse A, Laurent...Bargou RC, Daniel PT, Mapara MY, Bommert K, Wagener 96. Takahashi K, Sumimoto H, Suzuki K, Ono T: Protein syn- C, Kallinich B, Royer HD, Dorken B...signaling path- 18:3509-3517, 1998 way delivers an anti-apoptotic signal. Gene Dev 11: 701-713, 117. Wagener C, Bargou RC, Daniel PT, Bommert K, Mapara MY

  2. Nutrition and Performance at Environmental Extremes

    DTIC Science & Technology

    1994-01-01

    SNUTRITION in EXERCISE and SPORT 0_2nd Edition Si n l Editors F. -9. %im -a15 1994 Ira Wolinsky, Ph.D. Professor of Nutrition Department of Human...Reproduced From Boca Raton Ann Arbor Lo do.o appoved Best Available Copy J for p-H:•I .; -. !nd sIah: its 94 2 14 050 NUTRITION in EXERCISE and SPORT 2nd...Edition TTI C Editors ’• E FEB 15 1994 Ira Wolinsky, Ph.D. A Professor of Nutrition Department of Human Development University of Houston Houston

  3. Chronic red blood cell exchange to prevent clinical complications in sickle cell disease.

    PubMed

    Cabibbo, Sergio; Fidone, Carmelo; Garozzo, Giovanni; Antolino, Agostino; Manenti, Giovanna Oriella; Bennardello, Francesco; Licitra, Vincenzo; Calabrese, Salvatore; Costantino, Francesco; Travali, Simone; Distefano, Roberto; Bonomo, Pietro

    2005-06-01

    We tracked the results of 394 manual or automatic red blood cell exchanges done with a cell separator in 20 sickle cell patients at high risk for recurrent complications. Over an average of 6 years, none of the patients developed complications related to the procedure or to the increased blood use. It was safe and effective in preventing complications of sickle cell disease, and if done automatically, reduced iron overload. Ferritin levels also decreased in patients treated with automatic red blood cell exchange. Furthermore, using Single Donor Red Blood Cell units (SDRC) we reduced the potential exposure to transfusion transmitted infectious diseases (TTI).

  4. Air Force Global Weather Central System Architecture Study. Final System/Subsystem Summary Report. Volume 2. Requirements Compilation and Analysis. Part 1. User and Model Requirements

    DTIC Science & Technology

    1976-03-01

    functional characteristics of AFGWC in Section 3.0. ii wm ^wn^msr^ -- - ■ Y -•- >iMiiiiiiiiiia»iiri<iiiMl ■ ■ mmmm** ^^^~-m...8217■’■’ . WM inHMnwwnov-’ioRWX ’ «.’->"S-I",.W.Ä.’ -f.! V In ’ tti-t 3, an in-depth network analysis (Section 4.0) that depicts various key...Tracing Model I80 Conjugate Aurora Program 182 NOAA Ionospheric Scintillation Model ISS Macroscale and High Resolution Cloud Prognoses 164

  5. Low Speed Wind Tunnel Investigation of a .09 Scale, Navy Model T-2C Subsonic Jet Trainer Aircraft, from -8 to +83 Degrees Angle-of-Attack

    DTIC Science & Technology

    1973-12-31

    t, aHki^^^w^-^--^^^^ Y^TfTW^fpiBS^ WSJ ^ T^TTI^VT-: ’.;■ v i-"\\ r- "-;--::■■■- ’TT r ^^r- IADC-73259-30 0) ü h- Z hl -J Lü Q Q 2 O 5 < o...Ö 6.0 .CZI1 -. com -. 0060 -.0/29 - OMO -.03 29 -.0428 -.0H97 ■■05<ib •fo ,0101 -.00/9 -. Oo’lO - 0/ iH - 0Z¥t -.0335 -OH’ll -.0501 -.052.7 1 1.0

  6. An integrated GPS-FID system for airborne gas detection of pipeline right-of-ways

    SciTech Connect

    Gehue, H.L.; Sommer, P.

    1996-12-31

    Pipeline integrity, safety and environmental concerns are of prime importance in the Canadian natural gas industry. Terramatic Technology Inc. (TTI) has developed an integrated GPS/FID gas detection system known as TTI-AirTrac{trademark} for use in airborne gas detection (AGD) along pipeline right-of-ways. The Flame Ionization Detector (FID), which has traditionally been used to monitor air quality for gas plants and refineries, has been integrated with the Global Positioning System (GPS) via a 486 DX2-50 computer and specialized open architecture data acquisition software. The purpose of this technology marriage is to be able to continuously monitor air quality during airborne pipeline inspection. Event tagging from visual surveillance is used to determine an explanation of any delta line deviations (DLD). These deviations are an indication of hydrocarbon gases present in the plume that the aircraft has passed through. The role of the GPS system is to provide mapping information and coordinate data for ground inspections. The ground based inspection using a handheld multi gas detector will confirm whether or not a leak exists.

  7. High Earth orbit design for lunar assisted small Explorer class missions

    NASA Technical Reports Server (NTRS)

    Mathews, M.; Hametz, M.; Cooley, J.; Skillman, D.

    1994-01-01

    Small Expendable launch vehicles are capable of injecting modest payloads into high Earth orbits having apogee near the lunar distance. However, lunar and solar perturbations can quickly lower perigee and cause premature reentry. Costly perigee raising maneuvers by the spacecraft are required to maintain the orbit. In addition, the range of inclinations achievable is limited to those of launch sites unless costly spacecraft maneuvers are performed. This study investigates the use of a lunar swingby in a near-Hohmann transfer trajectory to raise perigee into the 8 to 25 solar radius range and reach a wide variety of inclinations without spacecraft maneuvers. It is found that extremely stable orbits can be obtained if the postencounter spacecraft orbital period is one-half of a lunar sidereal revolution and the Earth-vehicle-Moon geometry is within a specified range. Criteria for achieving stable orbits with various perigee heights and ecliptic inclinations are developed, and the sensitivity of the resulting mission orbits to transfer trajectory injection (TTI) errors is examined. It is shown that carefully designed orbits yield lifetimes of several years, with excellent ground station coverage characteristics and minimal eclipses. A phasing loop error correction strategy is considered with the spacecraft propulsion system delta V demand for TTI error correction and a postlunar encounter apogee trim maneuver typically in the 30 to 120 meters per second range.

  8. Passive thermal refugia provided warm water for Florida manatees during the severe winter of 2009-2010

    USGS Publications Warehouse

    Stith, B.M.; Slone, D.H.; de Wit, M.; Edwards, H.H.; Langtimm, C.A.; Swain, E.D.; Soderqvist, L.E.; Reid, J.P.

    2012-01-01

    Haloclines induced by freshwater inflow over tidal water have been identified as an important mechanism for maintaining warm water in passive thermal refugia (PTR) used by Florida manatees Trichechus manatus latirostris during winter in extreme southwestern Florida. Record-setting cold during winter 2009–2010 resulted in an unprecedented number of manatee deaths, adding to concerns that PTR may provide inadequate thermal protection during severe cold periods. Hydrological data from 2009–2010 indicate that 2 canal systems in the Ten Thousand Islands (TTI) region acted as PTR and maintained warm bottom-water temperatures, even during severe and prolonged cold periods. Aerial survey counts of live and dead manatees in TTI during the winter of 2009–2010 suggest that these PTR were effective at preventing mass mortality from hypothermia, in contrast to the nearby Everglades region, which lacks similar artificial PTR and showed high manatee carcass counts. Hydrological data from winter 2008–2009 confirmed earlier findings that without haloclines these artificial PTR may become ineffective as warm-water sites. Tidal pumping of groundwater appears to provide additional heat to bottom water during low tide cycles, but the associated thermal inversion is not observed unless salinity stratification is present. The finding that halocline-driven PTR can maintain warm water even under extreme winter conditions suggests that they may have significant potential as warm-water sites. However, availability and conflicting uses of freshwater and other management issues may make halocline-driven PTR unreliable or difficult to manage during winter.

  9. The effects of imagery training on fast isometric knee extensor torque development.

    PubMed

    de Ruiter, Cornelis J; Hutter, Vana; Icke, Chris; Groen, Bart; Gemmink, Anne; Smilde, Hiltsje; de Haan, Arnold

    2012-01-01

    We hypothesized that imagery training would improve the fast onset of neuromuscular activation and thereby fast knee extensor isometric torque development. Forty young healthy participants, not involved in strength training, were assigned to one of four groups: physical training, imagery training, placebo training or control. The three training groups had three 15 min sessions per week for 4 weeks, with a 90 ° knee angle but were tested also at 120 °. At 90 ° knee angle, maximal torque increased (-8%) similarly in all three training groups. The torque-time integral (contractile impulse) over the first 40 ms after torque onset (TTI40) increased (P < 0.05) after physical training (by -100%), but only at 90 °. This increase was significantly different from the delta values (change pre to post) in the control and placebo groups, whereas delta values in the imagery group were similar to those in the placebo group. The increases in TTI40 following physical training were related (r (2) = 0.81, P < 0.05) to significant increases of knee extensor rectified surface EMG at torque onset (EMG40). In conclusion, only physical training led to a knee angle specific increase of contractile impulse that was significantly different from placebo and controls and that was related to improved onset of neuromuscular activation.

  10. Optimization of Forward Wave Modeling on Contemporary HPC Architectures

    SciTech Connect

    Krueger, Jens; Micikevicius, Paulius; Williams, Samuel

    2012-07-20

    Reverse Time Migration (RTM) is one of the main approaches in the seismic processing industry for imaging the subsurface structure of the Earth. While RTM provides qualitative advantages over its predecessors, it has a high computational cost warranting implementation on HPC architectures. We focus on three progressively more complex kernels extracted from RTM: for isotropic (ISO), vertical transverse isotropic (VTI) and tilted transverse isotropic (TTI) media. In this work, we examine performance optimization of forward wave modeling, which describes the computational kernels used in RTM, on emerging multi- and manycore processors and introduce a novel common subexpression elimination optimization for TTI kernels. We compare attained performance and energy efficiency in both the single-node and distributed memory environments in order to satisfy industry’s demands for fidelity, performance, and energy efficiency. Moreover, we discuss the interplay between architecture (chip and system) and optimizations (both on-node computation) highlighting the importance of NUMA-aware approaches to MPI communication. Ultimately, our results show we can improve CPU energy efficiency by more than 10× on Magny Cours nodes while acceleration via multiple GPUs can surpass the energy-efficient Intel Sandy Bridge by as much as 3.6×.

  11. A gain-of-function senescence bypass screen identifies the homeobox transcription factor DLX2 as a regulator of ATM–p53 signaling

    PubMed Central

    Wang, Yifan; Xu, Qikai; Sack, Laura; Kang, Chanhee; Elledge, Stephen J.

    2016-01-01

    Senescence stimuli activate multiple tumor suppressor pathways to initiate cycle arrest and a differentiation program characteristic of senescent cells. We performed a two-stage, gain-of-function screen to select for the genes whose enhanced expression can bypass replicative senescence. We uncovered multiple genes known to be involved in p53 and Rb regulation and ATM regulation, two components of the CST (CTC1–STN1–TEN1) complex involved in preventing telomere erosion, and genes such as REST and FOXO4 that have been implicated in aging. Among the new genes now implicated in senescence, we identified DLX2, a homeobox transcription factor that has been shown to be required for tumor growth and metastasis and is associated with poor cancer prognosis. Growth analysis showed that DLX2 expression led to increased cellular replicative life span. Our data suggest that DLX2 expression reduces the protein components of the TTI1/TTI2/TEL2 complex, a key complex required for the proper folding and stabilization of ATM and other members of the PIKK (phosphatidylinositol 3-kinase-related kinase) family kinase, leading to reduced ATM–p53 signaling and senescence bypass. We also found that the overexpression of DLX2 exhibited a mutually exclusive relationship with p53 alterations in cancer patients. Our functional screen identified novel players that may promote tumorigenesis by regulating the ATM–p53 pathway and senescence. PMID:26833729

  12. Tensile and burning properties of clay/phenolic/GF composite and its application

    NASA Astrophysics Data System (ADS)

    Diharjo, Kuncoro; Armunanto, V. Bram; Kristiawan, S. Adi

    2016-03-01

    Composite material has been widely used in automotive due to its properties can be improved by combining with reinforcement, like fiber and particle to enhance mechanical properties and burning resistance. This study aims to investigate the tensile and burning properties of hybrid composite combining glass fiber and clay in phenolic resin. The clay was produced from roof tile rejected by tile industries in Sokka, Kebumen, Indonesia. The composite was made using a press mold method for different number of laminates and orientation of woven-roving-glass-fiber/ WRGF (0/90 and ±45), and the total volume fraction of fiber and clay is constant 40%. The specimens were tested using universal testing machine for tensile properties and burning tests apparatus for burning resistance (time to ignite/ TTI and burning rate/ BR). The enhancing of the Clay/Penolic/GF composite can be performed by the increasing of GF laminates, and the composite with 0/90 orientation of WRGF has higher tensile strength and modulus compared to that with ±45 orientation of WRGF. Both composite with 0/90 and ±45 orientation of WRGF have similar burning resistance (TTI and BR) and the composite containing 13 laminates of WR-GF shows the best burning resistance. According to these properties, this composite has good opportunity to be applied as car body panels or other structure in industries due to save weight and high burning resistance.

  13. Thermoregulatory responses during exercise and a hot water immersion and the affective responses to peripheral thermal stimuli

    NASA Astrophysics Data System (ADS)

    Fujishima, K.

    1986-03-01

    Tympanic (Tty), mean skin (¯Tsk) and mean body (¯Tb) temperatures and heart rate (HR) increased more in low Vo2 max group (LG) than in high Vo2 max group (HG) during exercise. The regression coefficient of body temperatures (Tty and ¯Tb) on HR and the increased rate of heat storage were larger in LG than in HG during exercise. The local sweat rate (per min/cm2) during a hot water bath exhibited a considerable large quantity in comparison with the amount during exercise. Internal and skin temperatures during a hot water bath increased more immediately than those during exercise. The levels of comfort sensation during the preovulatory phase in women and pre-exercise period in men were higher at 40‡C than at 20‡C as peripheral thermal stimulus. The levels during the postovulatory and post-exercise phases in the same subjects were higher with the cool stimuli than with the warm stimuli. Above results suggest that thermoregulatory responses during submaximal exercise are different according to physical fitness and that these responses are different from those during hot water immersion. In addition, these suggest that the scores of thermal sensation with warm and cool stimuli are different during the pre- and post-ovulatory phases and the pre- and post-exercise periods.

  14. Tracking magmatic processes through Zr/Hf ratios in rocks and Hf and Ti zoning in zircons: An example from the Spirit Mountain batholith, Nevada

    USGS Publications Warehouse

    Lowery, Claiborne L.E.; Miller, C.F.; Walker, B.A.; Wooden, J.L.; Mazdab, F.K.; Bea, F.

    2006-01-01

    Zirconium and Hf are nearly identical geochemically, and therefore most of the crust maintains near-chondritic Zr/Hf ratios of ???35-40. By contrast, many high-silica rhyolites and granites have anomalously low Zr/Hf (15-30). As zircon is the primary reservoir for both Zr and Hf and preferentially incorporates Zr, crystallization of zircon controls Zr/ Hf, imprinting low Zr/Hf on coexisting melt. Thus, low Zr/Hf is a unique fingerprint of effective magmatic fractionation in the crust. Age and compositional zonation in zircons themselves provide a record of the thermal and compositional histories of magmatic systems. High Hf (low Zr/ Hf) in zircon zones demonstrates growth from fractionated melt, and Ti provides an estimate of temperature of crystallization (TTiZ) (Watson and Harrison, 2005). Whole-rock Zr/Hf and zircon zonation in the Spirit Mountain batholith, Nevada, document repeated fractionation and thermal fluctuations. Ratios of Zr/Hf are ???30-40 for cumulates and 18-30 for high-SiO2 granites. In zircons, Hf (and U) are inversely correlated with Ti, and concentrations indicate large fluctuations in melt composition and TTiZ (>100??C) for individual zircons. Such variations are consistent with field relations and ion-probe zircon geochronology that indicate a >1 million year history of repeated replenishment, fractionation, and extraction of melt from crystal mush to form the low Zr/Hf high-SiO2 zone. ?? 2006 The Mineralogical Society.

  15. Seasonal acclimation in sudomotor function evaluated by QSART in healthy humans

    PubMed Central

    Shin, Young Oh; Kim, Jeong-Ho

    2016-01-01

    The quantitative sudomotor axon reflex testing (QSART) is a classic test of routine postganglionic sudomotor function. We investigated sudomotor function by QSART after summer (July 2012) and winter (January 2013) seasonal acclimation (SA) in the Republic of Korea. QSART with acetylcholine (ACh) iontophoresis were performed to determine directly activated (DIR) and axon reflex-mediated (AXR1, 2) sweating rate. Onset time of axon reflex, activated sweat gland density (ASGD), activated sweat gland output (ASGO), tympanic and skin temperatures (Tty, Tsk), basal metabolic rate (BMR), and evaporative loss volume changes were measured. Tympanic and mean body temperature (Tb; calculated from Tty, Tsk) were significantly lower after summer-SA than that of winter-SA. Sweat onset time was delayed during winter-SA compared to that after summer-SA. BMR, AXR(1), AXR(2), and DIR sweat rates, ASGD and ASGO, and evaporative loss volume were significantly diminished after winter-SA relative to after summer-SA. In conclusion, changes in sweating activity measured by QSART confirmed the involvement of the peripheral nervous system in variation of sudomotor activity in seasonal acclimation. PMID:27610036

  16. Nucleic acid testing (NAT) in high prevalence-low resource settings.

    PubMed

    El Ekiaby, Magdy; Lelie, Nico; Allain, Jean-Pierre

    2010-01-01

    Blood screening by NAT for major transfusion transmitted viral infections (TTIs) was originally intended to complement serology for detection of infected donations. Reports from developed countries showed limited marginal value to NAT blood screening in improving blood safety. Reports on NAT results from Europe indicated yield of 1:0.6 million donations for HBV, <1:M for HCV and HIV-1-related to low prevalence of TTI. In contrast, prevalence of TTI in resource-limited countries is almost always high. As a result, more incident cases can be expected among first-time blood donors. Most reports of NAT blood donation screening in these countries showed NAT confirmed yield as high as 1/2800 for HBV and 1/3100 blood donations for HCV as reported from Thailand and Egypt, respectively. The issues for low resource countries are mostly the high cost of NAT but also the requirements of staff qualification, adequate facilities, reagent procurement and maintenance of delicate equipment. Alternatives to commercial NAT are the use of combos antigen-antibody for HIV and HCV, anti-HBc for HBV and in-house NAT. Most of these alternatives have been reported but very few comparisons are available. Once yield data is available, models for estimation of feasibility and cost-effectiveness are proposed to help decision-making.

  17. Thermal changes observed before and after J.-L. Etienne's journey to the North Pole. Is central nervous system temperature preserved in hypothermia?

    PubMed

    Bittel, J H; Livecchi-Gonnot, G H; Hanniquet, A M; Poulain, C; Etienne, J L

    1989-01-01

    The thermoregulatory responses of a French doctor, Jean-Louis Etienne, were examined in a standard cold test before and after his journey to the North Pole, to investigate whether general and/or local cold adaptation had occurred. The two tests were carried out in a climatic chamber for 2 h at rest (dry bulb temperature, 1 degree C; relative humidity, 40%; wind speed, 0.8 m.s-1). After his journey, Etienne showed a general hypothermic-hypometabolic adaptation, i.e. a decrease in rectal temperature (Tre) and metabolic heat production (M), and an increased local skin temperature of the extremities. Between the two tests, a change occurred in the relationship between tympanic temperature (Tty) and M. During the post-journey cold test, Tty [as representative of the central nervous system (CNS) temperature] increased while the decrease in Tre was accelerated, probably due to a redistribution of blood volume towards the CNS. Such a mechanism would protect the central core with special reference to the CNS.

  18. Stability analysis for acoustic wave propagation in tilted TI media by finite differences

    NASA Astrophysics Data System (ADS)

    Bakker, Peter M.; Duveneck, Eric

    2011-05-01

    Several papers in recent years have reported instabilities in P-wave modelling, based on an acoustic approximation, for inhomogeneous transversely isotropic media with tilted symmetry axis (TTI media). In particular, instabilities tend to occur if the axis of symmetry varies rapidly in combination with strong contrasts of medium parameters, which is typically the case at the foot of a steeply dipping salt flank. In a recent paper, we have proposed and demonstrated a P-wave modelling approach for TTI media, based on rotated stress and strain tensors, in which the wave equations reduce to a coupled set of two second-order partial differential equations for two scalar stress components: a normal component along the variable axis of symmetry and a lateral component of stress in the plane perpendicular to that axis. Spatially constant density is assumed in this approach. A numerical discretization scheme was proposed which uses discrete second-derivative operators for the non-mixed second-order derivatives in the wave equations, and combined first-derivative operators for the mixed second-order derivatives. This paper provides a complete and rigorous stability analysis, assuming a uniformly sampled grid. Although the spatial discretization operator for the TTI acoustic wave equation is not self-adjoint, this operator still defines a complete basis of eigenfunctions of the solution space, provided that the solution space is somewhat restricted at locations where the medium is elliptically anisotropic. First, a stability analysis is given for a discretization scheme, which is purely based on first-derivative operators. It is shown that the coefficients of the central difference operators should satisfy certain conditions. In view of numerical artefacts, such a discretization scheme is not attractive, and the non-mixed second-order derivatives of the wave equation are discretized directly by second-derivative operators. It is shown that this modification preserves

  19. Normal values for inspiratory muscle function in children.

    PubMed

    Mellies, Uwe; Stehling, Florian; Dohna-Schwake, Christian

    2014-10-01

    Assessment of inspiratory muscle function (IMF) is limited in children with neuromuscular disorders, because respiratory muscle tests are poorly standardized and valid normative data are unavailable. We investigated maximum inspiratory pressure after exhalation to residual volume (MIP), mouth occlusion pressure (P0.1) and time of inspiration during quiet breathing and derived inspiratory muscle load (P0.1/MIP), and tension time index (TTI) in 301 healthy schoolchildren 6-16 years old. Gender-specific and age-dependent percentile curves for MIP were drawn with the median, 5%, 10%, 25%, 75% and 95% percentile. P0.1 was equal in boys and girls (0.23  ±  0.11 kPa), while MIP was significantly higher in boys (6.8  ±  2.2 versus 5.8  ±  2.4 kPa). Consequently, P0.1/MIP (4.8% ± 3.2% versus 4.0% ± 3.1%) and TTI (0.2  ±  0.14 versus 0.16  ±  0.14) were significantly higher in girls. MIP was 2.90 + 0.36 × age (kPa) and 3.19 + 0.24 × age (kPa) in boys and girls, respectively. The 95% confidence intervals for boys and girls, respectively, were MIP, 6.3-7.3 kPA and 5.4-6.2 kPa; P0.1/MIP, 3.5%-4.5% and 4.3%-5.3%; TTI, 0.14-0.18 and 0.18-0.22; and P0.1, 0.20-0.24 kPa for both. IMF in children has a wide interindividual variability; however percentile curves facilitate a longitudinal assessment of individual patients. Furthermore, narrow confidence intervals allow for comparisons of study populations, making IMF an appropriate endpoint for clinical trials.

  20. Continuous Non-Invasive Monitoring of Tidal Volumes by Measurement of Tidal Impedance in Neonatal Piglets

    PubMed Central

    Kurth, Florian; Zinnow, Fabienne; Prakapenia, Alexandra; Dietl, Sabrina; Winkler, Stefan; Ifflaender, Sascha; Rüdiger, Mario; Burkhardt, Wolfram

    2011-01-01

    Background Electrical Impedance measurements can be used to estimate the content of intra-thoracic air and thereby give information on pulmonary ventilation. Conventional Impedance measurements mainly indicate relative changes, but no information concerning air-volume is given. The study was performed to test whether a 3-point-calibration with known tidal volumes (VT) during conventional mechanical ventilation (CMV) allows subsequent calculation of VT from total Tidal-Impedance (tTI) measurements using Quadrant Impedance Measurement (QIM). In addition the distribution of TI in different regions of the thorax was examined. Methodology and Principal Findings QIM was performed in five neonatal piglets during volume-controlled CMV. tTI values at three different VT (4, 6, 8 ml/kg) were used to establish individual calibration curves. Subsequently, each animal was ventilated with different patterns of varying VT (2–10 ml/kg) at different PEEP levels (0, 3, 6, 9, 12 cmH2O). VT variation was repeated after surfactant depletion by bronchoalveolar lavage. VT was calculated from tTI values (VTcalc) and compared to the VT delivered by the ventilator (VTPNT). Bland-Altman analysis revealed good agreement between VTcalc and VTPNT before (bias −0.08 ml; limits of agreement −1.18 to 1.02 ml at PEEP = 3 cmH2O) and after surfactant depletion (bias −0.17 ml; limits of agreement −1.57 to 1.22 ml at PEEP = 3 cmH2O). At higher PEEP levels VTcalc was lower than VTPNT, when only one fixed calibration curve (at PEEP 3 cmH2O) was used. With a new calibration curve at each PEEP level the method showed similar accuracy at each PEEP level. TI showed a homogeneous distribution over the four assessed quadrants with a shift toward caudal regions of the thorax with increasing VT. Conclusion Tidal Impedance values could be used for precise and accurate calculation of VT during CMV in this animal study, when calibrated at each PEEP level. PMID:21687746

  1. Comparison of the Pentax Airwayscope, Glidescope Video Laryngoscope, and Macintosh Laryngoscope During Chest Compression According to Bed Height

    PubMed Central

    Kim, Wonhee; Lee, Yoonje; Kim, Changsun; Lim, Tae Ho; Oh, Jaehoon; Kang, Hyunggoo; Lee, Sanghyun

    2016-01-01

    Abstract We aimed to investigate whether bed height affects intubation performance in the setting of cardiopulmonary resuscitation and which type of laryngoscope shows the best performance at each bed height. A randomized crossover manikin study was conducted. Twenty-one participants were enrolled, and they were randomly allocated to 2 groups: group A (n = 10) and group B (n = 11). The participants underwent emergency endotracheal intubation (ETI) using the Airwayscope (AWS), Glidescope video laryngoscope, and Macintosh laryngoscope in random order while chest compression was performed. Each ETI was conducted at 2 levels of bed height (minimum bed height: 68.9 cm and maximum bed height: 101.3 cm). The primary outcomes were the time to intubation (TTI) and the success rate of ETI. The P value for statistical significance was set at 0.05 and 0.017 in post-hoc test. The success rate of ETI was always 100% regardless of the type of laryngoscope or the bed height. TTI was not significantly different between the 2 bed heights regardless of the type of laryngoscope (all P > 0.05). The time for AWS was the shortest among the 3 laryngoscopes at both bed heights (13.7 ± 3.6 at the minimum bed height and 13.4 ± 4.7 at the maximum bed height) (all P < 0.017). The TTI of Glidescope video laryngoscope was not significantly shorter than that of Macintosh laryngoscope at the minimum height (17.6 ± 4.0 vs 19.6 ± 4.8; P = 0.02). The bed height, whether adjusted to the minimum or maximum setting, did not affect intubation performance. In addition, regardless of the bed height, the intubation time with the video laryngoscopes, especially AWS, was significantly shorter than that with the direct laryngoscope during chest compression. PMID:26844477

  2. What does tympanostomy tube placement in children teach us about the association between atopic conditions and otitis media?

    PubMed

    Juhn, Young J; Wi, Chung-Il

    2014-07-01

    Otitis media is the most common infection second only to viral upper respiratory infection in the outpatient setting. Tympanostomy tube insertion (TTI) is the most common ambulatory surgical procedure in the USA. While many risk factors for otitis media have been identified, atopic conditions have been underrecognized as risk factors for recurrent and persistent otitis media. Given that asthma and other atopic conditions are the most common chronic conditions during childhood, it is worth examining the association between atopic conditions and risk of otitis media, which can provide insight into how atopic conditions influence the risk of microbial infections. This paper focuses its discussion on otitis media; however, it is important that the association between atopic conditions and risk of otitis media be interpreted in the context of the association of atopic conditions with increased risks of various microbial infections.

  3. Spray Nozzles, Pressures, Additives and Stirring Time on Viability and Pathogenicity of Entomopathogenic Nematodes (Nematoda: Rhabditida) for Greenhouses

    PubMed Central

    Moreira, Grazielle Furtado; Batista, Elder Simões de Paula; Campos, Henrique Borges Neves; Lemos, Raphael Emilio; Ferreira, Marcelo da Costa

    2013-01-01

    The objective of this study was to evaluate different strategies for the application of entomopathogenic nematodes (EPN). Three different models of spray nozzles with air induction (AI 11003, TTI 11003 and AD-IA 11004), three spray pressures (207, 413 and 720 kPa), four different additives for tank mixtures (cane molasses, mineral oil, vegetable oil and glycerin) and the influence of tank mixture stirring time were all evaluated for their effect on EPN (Steinernema feltiae) viability and pathogenicity. The different nozzles, at pressures of up to 620 kPa, were found to be compatible with S. feltiae. Vegetable oil, mineral oil and molasses were found to be compatible adjuvants for S. feltiae, and stirring in a motorized backpack sprayer for 30 minutes did not impact the viability or pathogenicity of this nematode. Appropriate techniques for the application of nematodes with backpack sprayers are discussed. PMID:23755280

  4. Jet decorrelation and jet shapes at the Tevatron

    SciTech Connect

    Heuring, T.C.

    1996-07-01

    We present results on measurements of jet shapes and jet azimuthal decorrelation from {bar p}P collisions at {radical}s = 1.8 TeV using data collected during the 1992-1993 run of the Fermilab Tevatron. Jets are seen to narrow both with increasing Awe {sub TTY} and increasing rapidity. While HERWIG, a puritan shower Monte Carlo, predicts slightly narrower jets, it describes the trend of the data well; NO CD described qualitative features of the data but is sensitive to both renormalization scale and jet definitions. Jet azimuthal decorrelation has been measured out to five units of pseudorapidity. While next-to-leading order CD and a leading-log approximation based on BFKL resummation fail to reproduce the effect, HERWIG describes the data well.

  5. INM Integrated Noise Model Version 2. Programmer’s Guide

    DTIC Science & Technology

    1979-09-01

    USED. THE NORMA ! RETURN IS AT TINE 11 AND IS USED C IF THE RET.RN AT TINE S IS ICT USED. C THE VAPTBLE Tv I1 1BELED C).3CN BLOCK/ASDS23/IS SET EQUAL...Y tSi’MIS WE P~ APA " l r TB POIVTIJF. lI?. 1-1 -,TC**’ ASSIG! F.WrS POP EACH TRACK. /411W vr VIN-) V!-1:CcTTY (KXCTS) F’OR EACH GRUP r j~l-’ 7in Dri...DESCRIPTION C /RtINWAY/ APALT AIRPCOT ALTITUDE ABOVE MEAN SEA LEVLE. C /R’TFVAY/ APA !I AIPPORT ALTITUDE ArO"VE MEAN SEA LEVLE. C .1PT ElAP AVERAGE

  6. Combustion characteristics of bamboo-biochars.

    PubMed

    Liu, Zhijia; Fei, Benhua; Jiang, Zehui; Liu, Xing'e

    2014-09-01

    Combustion characteristics of biomass are very important to directly utilize as an energy resource. Bamboo was carbonized using a XD-1200N muffle furnace in the nitrogen environment and its combustion characteristics were investigated. Results showed that bamboo-biochars had better combustion characteristics compared to bamboo materials, such as a lower content of moisture and volatiles, a higher energy density, HHV and EHC, a lower H/C and O/C ratios and a shorter TTI. Characteristic peak of bamboo-biochars shifted to higher temperature in thermal decomposition process, indicating a more steady-state burning and a higher combustion efficiency. Bamboo-biochars had a low content of S and N, which was helpful to decrease pollutant emissions. A higher content of K and Na was observed in the ash of bamboo-biochars, resulting in slagging, fouling, corrosion and agglomeration. The data from this research will be very helpful to efficiently design and operate its combustion systems.

  7. Laboratory data manipulation tools basic data handling programs. Volume 2: Detailed software/hardware documentation

    NASA Technical Reports Server (NTRS)

    1981-01-01

    The set of computer programs described allows for data definition, data input, and data transfer between the LSI-11 microcomputers and the VAX-11/780 minicomputer. Program VAXCOM allows for a simple method of textual file transfer from the LSI to the VAX. Program LSICOM allows for easy file transfer from the VAX to the LSI. Program TTY changes the LSI-11 operators console to the LSI's printing device. Program DICTIN provides a means for defining a data set for input to either computer. Program DATAIN is a simple to operate data entry program which is capable of building data files on either machine. Program LEDITV is an extremely powerful, easy to use, line oriented text editor. Program COPYSBF is designed to print out textual files on the line printer without character loss from FORTRAN carriage control or wide record transfer.

  8. Angle-domain common-image gathers from anisotropic Gaussian beam migration and its application to anisotropy-induced imaging errors analysis

    NASA Astrophysics Data System (ADS)

    Han, Jianguang; Wang, Yun; Yu, Changqing; Chen, Peng

    2017-02-01

    An approach for extracting angle-domain common-image gathers (ADCIGs) from anisotropic Gaussian beam prestack depth migration (GB-PSDM) is presented in this paper. The propagation angle is calculated in the process of migration using the real-value traveltime information of Gaussian beam. Based on the above, we further investigate the effects of anisotropy on GB-PSDM, where the corresponding ADCIGs are extracted to assess the quality of migration images. The test results of the VTI syncline model and the TTI thrust sheet model show that anisotropic parameters ɛ, δ, and tilt angle 𝜃, have a great influence on the accuracy of the migrated image in anisotropic media, and ignoring any one of them will cause obvious imaging errors. The anisotropic GB-PSDM with the true anisotropic parameters can obtain more accurate seismic images of subsurface structures in anisotropic media.

  9. DABI: A data base for image analysis with nondeterministic inference capability

    NASA Technical Reports Server (NTRS)

    Yakimovsky, Y.; Cunningham, R.

    1976-01-01

    A description is given of the data base used in the perception subsystem of the Mars robot vehicle prototype being implemented at the Jet Propulsion Laboratory. This data base contains two types of information. The first is generic (uninstantiated, abstract) information that specifies the general rules of perception of objects in the expected environments. The second kind of information is a specific (instantiated) description of a structure, i.e., the properties and relations of objects in the specific case being analyzed. The generic knowledge can be used by the approximate reasoning subsystem to obtain information on the specific structures which is not directly measurable by the sensory instruments. Raw measurements are input either from the sensory instruments or a human operator using a CRT or a TTY.

  10. "Can you see me now?" An objective metric for predicting intelligibility of compressed American Sign Language video

    NASA Astrophysics Data System (ADS)

    Ciaramello, Francis M.; Hemami, Sheila S.

    2007-02-01

    For members of the Deaf Community in the United States, current communication tools include TTY/TTD services, video relay services, and text-based communication. With the growth of cellular technology, mobile sign language conversations are becoming a possibility. Proper coding techniques must be employed to compress American Sign Language (ASL) video for low-rate transmission while maintaining the quality of the conversation. In order to evaluate these techniques, an appropriate quality metric is needed. This paper demonstrates that traditional video quality metrics, such as PSNR, fail to predict subjective intelligibility scores. By considering the unique structure of ASL video, an appropriate objective metric is developed. Face and hand segmentation is performed using skin-color detection techniques. The distortions in the face and hand regions are optimally weighted and pooled across all frames to create an objective intelligibility score for a distorted sequence. The objective intelligibility metric performs significantly better than PSNR in terms of correlation with subjective responses.

  11. Spray nozzles, pressures, additives and stirring time on viability and pathogenicity of entomopathogenic nematodes (nematoda: rhabditida) for greenhouses.

    PubMed

    Moreira, Grazielle Furtado; Batista, Elder Simões de Paula; Campos, Henrique Borges Neves; Lemos, Raphael Emilio; Ferreira, Marcelo da Costa

    2013-01-01

    The objective of this study was to evaluate different strategies for the application of entomopathogenic nematodes (EPN). Three different models of spray nozzles with air induction (AI 11003, TTI 11003 and AD-IA 11004), three spray pressures (207, 413 and 720 kPa), four different additives for tank mixtures (cane molasses, mineral oil, vegetable oil and glycerin) and the influence of tank mixture stirring time were all evaluated for their effect on EPN (Steinernema feltiae) viability and pathogenicity. The different nozzles, at pressures of up to 620 kPa, were found to be compatible with S. feltiae. Vegetable oil, mineral oil and molasses were found to be compatible adjuvants for S. feltiae, and stirring in a motorized backpack sprayer for 30 minutes did not impact the viability or pathogenicity of this nematode. Appropriate techniques for the application of nematodes with backpack sprayers are discussed.

  12. Past, current and potential utilisation of active and intelligent packaging systems for meat and muscle-based products: A review.

    PubMed

    Kerry, J P; O'Grady, M N; Hogan, S A

    2006-09-01

    Interest in the use of active and intelligent packaging systems for meat and meat products has increased in recent years. Active packaging refers to the incorporation of additives into packaging systems with the aim of maintaining or extending meat product quality and shelf-life. Active packaging systems discussed include oxygen scavengers, carbon dioxide scavengers and emitters, moisture control agents and anti-microbial packaging technologies. Intelligent packaging systems are those that monitor the condition of packaged foods to give information regarding the quality of the packaged food during transport and storage. The potential of sensor technologies, indicators (including integrity, freshness and time-temperature (TTI) indicators) and radio frequency identification (RFID) are evaluated for potential use in meat and meat products. Recognition of the benefits of active and intelligent packaging technologies by the food industry, development of economically viable packaging systems and increased consumer acceptance is necessary for commercial realisation of these packaging technologies.

  13. Solid State Research, 1981:2.

    DTIC Science & Technology

    1981-05-15

    took place in the same mariner as in thre two-Ireate c I.K SS explecimerits wvhern the upperc strip- freater was nio (’( parallel to the long axis Of tire...at’s it) lave dco-rcastd. Although l.tit iI it(:I K tti( "i f tilt ,.xvgt,’n 1)twoi - li,’ dtep..sito d tungst .’tt and silicon films cannot io pr, Ci- k...its of tlh,-,- Aug. I- ala lv. s is that tho tungst ’i filnt con- tairts, som lcvI of oxvg.’n dth. to ite( gf-tt.ring of r( siduial toxvgi n int lt

  14. Effect of single flame retardant aluminum tri-hydroxide and boric acid against inflammability and biodegradability of recycled PP/KF composites

    NASA Astrophysics Data System (ADS)

    Suharty, Neng Sri; Dihardjo, Kuncoro; Handayani, Desi Suci; Firdaus, Maulidan

    2016-03-01

    Composites rPP/DVB/AA/KF had been reactively synthesized in melt using starting material: recycled polypropylene (rPP), kenaf fiber (KF), multifunctional compound acrylic acid (AA), compatibilizer divinyl benzene (DVB). To improve the inflammability of composites, single flame retardant aluminum tri-hydroxide (ATH) and boric acid (BA) as an additive was added. The inflammability of the composites was tested according to ASTM D635. By using 20% ATH and 5% BA additive in the composites it is effectively inhibiting its time to ignition (TTI). Its burning rate (BR) can be reduced and its heat realease (%HR) decreases. The biodegradability of composites was quantified by its losing weight (LW) of composites after buried for 4 months in the media with rich cellulolytic bacteria. The result shows that the LW of composites in the presence 20% ATH and 5% BA is 6.3%.

  15. Ramstein AB, Germany (West). Revised Uniform Summary of Surface Weather Observations (RUSSWO). Parts A-F.

    DTIC Science & Technology

    1982-07-21

    97.7 97.7 97.7 97.7 -a 969-.1 A T97 o -0 98.1 98.1 9A.1 98. 1 b3.1 92*6 94J 9497 979i 98.3 98.8 98.8 98.8 98.8 98.8. 98.8 9808 98.8 98.8 98.8 - 37V-2...65.418.656 669- oF 1-32F &67F A734 - 80F 9 F T.t.i-4. 6 1 -.18-0 669S 7.9 89-.6 40.0- 8.1. i Nb 35 07132 31 322599 65.1 6.988 6695 14 0 1 .6 7*4 m Do

  16. F-16 Simulator for Man-in-the-Loop Testing of Aircraft Control Systems (SIMTACS).

    DTIC Science & Technology

    1987-12-01

    AD-4199 675 F-16 SIMULA TR FOR MAN-JN-THE- JO TTI M? OF AIRCR"F7 L/2 CONTROL M IS (SjMTAC~ )(U) AHOFQC IN T OFT0 UNCLASSIFIED DE 8 A FJ7CTI 3NCKO7O...OF GNI. 4 HLS 󈧨 - Il1.8 IIIIi .25 1.4 1.6 MICROCOPY RESOLUTION T ES r CHART --- .- u,...,n..nmmnmmna,.,mn mmi ihh’nunan immii u N: 9 It ILL 0...belief in my ability to accomplish this task. Acce slon For t NTIS3 FA&I ti :’ ’,. u " ii jj... W\\i U t At .. .. ..) Page Preface

  17. Changes in EEG activity before and after exhaustive exercise in sedentary women in neutral and hot environments.

    PubMed

    Ftaiti, Foued; Kacem, Asma; Jaidane, Nadia; Tabka, Zouhair; Dogui, Mohamed

    2010-10-01

    This study examined the effect of hyperthermia on brain electrical activity measured with encephalography during prolonged exhaustive exercise in a group of sedentary women (VO(2)max = 35 +/- 4 mL kg min(-1)). Two strenuous cycling exercises were performed either in neutral (N-Ex) or in heat (H-Ex) conditions. Tympanic temperature (Tty), heart rate (HR), body mass loss (BML), plasma volume decrease, and brain electrical activity [EEG: alpha (8-13 Hz) and beta(13-30 Hz)-band and alpha/beta index of fatigue: the ratio between EEG activity in the alpha band and beta-band] were recorded throughout the cycling sessions. The Tty increase 1.0 degrees C in the N-Ex and 1.8 degrees C in H-Ex. HR increased in both sessions but with significantly higher values during the H-Ex session when compared with the N-Ex session (p < 0.001) (from 85 +/- 4 beats min(-1) to 164 +/- 6 beats min(-1) and from 83 +/- 6 beats min(-1) to 181 +/- 8 beats min(-1), respectively in N-Ex and in H-Ex). This was associated with a significantly higher BML (p < 0.05) and a higher plasma volume decrease in the H-Ex session (p < 0.01). The alpha/beta index increased significantly during both trials particularly during the H-Ex session (p < 0.05). This was associated with a significant decrease of time to exhaustion (-34%). We suggest that exhausting work in the heat induced a change in gross brain activity (alpha/beta ratio) compared to a longer, less thermally demanding exposure. Fatigue in the heat could be attributed to central factors as well as thermal, cardiac and hydro-electrolytic impairment.

  18. Prediction of severe thunderstorms over Sriharikota Island by using the WRF-ARW operational model

    NASA Astrophysics Data System (ADS)

    Papa Rao, G.; Rajasekhar, M.; Pushpa Saroja, R.; Sreeshna, T.; Rajeevan, M.; Ramakrishna, S. S. V. S.

    2016-05-01

    Operational short range prediction of Meso-scale thunderstorms for Sriharikota(13.7°N ,80.18°E) has been performed using two nested domains 27 & 9Km configuration of Weather Research & Forecasting-Advanced Research Weather Model (WRF- ARW V3.4).Thunderstorm is a Mesoscale system with spatial scale of few kilometers to a couple of 100 kilometers and time scale of less than an one hour to several hours, which produces heavy rain, lightning, thunder, surface wind squalls and down-bursts. Numerical study of Thunderstorms at Sriharikota and its neighborhood have been discussed with its antecedent thermodynamic stability indices and Parameters that are usually favorable for the development of convective instability based on WRF ARW model predictions. Instability is a prerequisite for the occurrence of severe weather, the greater the instability, the greater will be the potential of thunderstorm. In the present study, K Index, Total totals Index (TTI), Convective Available Potential Energy (CAPE), Convective Inhibition Energy (CINE), Lifted Index (LI), Precipitable Water (PW), etc. are the instability indices used for the short range prediction of thunderstorms. In this study we have made an attempt to estimate the skill of WRF ARW predictability and diagnosed three thunderstorms that occurred during the late evening to late night of 31st July, 20th September and 2nd October of 2015 over Sriharikota Island which are validated with Local Electric Field Mill (EFM), rainfall observations and Chennai Doppler Weather Radar products. The model predicted thermodynamic indices (CAPE, CINE, K Index, LI, TTI and PW) over Sriharikota which act as good indicators for severe thunderstorm activity.

  19. Just-in-Time Video Laryngoscopy Versus Direct Laryngoscopy for Neonatal Intubation.

    PubMed

    Grgurich, Erin; Arnemann, Cynthia; Amon, Kim; Horton, Rose; Carlson, Jestin N

    As neonatal endotracheal intubation (ETI) is a low-frequency, high-consequence event, it is essential that providers have access to resources to aid in ETI. We sought to determine the impact of video laryngoscopy (VL) with just-in-time training on intubation outcomes over direct laryngoscopy (DL) when performed by neonatal nurses. We conducted a prospective, randomized, crossover study with neonatal nurses employed at a level 2 neonatal intensive care unit (NICU). Nurses performed both DL and VL on a neonatal mannequin using a CMAC (Karl Storz Corp, Tuttlingen, Germany) either with the assistance of the screen (VL) or without (DL). Before performing the intubation, providers were given a just-in-time, brief education presentation and allowed to practice with the device. Each ETI attempt was reviewed to obtain the percentage of glottic opening (POGO) score, time to intubation (TTI, time from insertion of the blade into the mouth until the first breath was delivered), and time from blade insertion until the best POGO score. We enrolled 19 participants, with a median (interquartile range) of 20 (9-26) years of experience and having a median of 2 (1-3) intubations within the past year. None had used VL in the NICU previously. Median TTI did not differ between DL and VL: 19.9 (15.3-41.5) vs 20.3 (17.9-24.4) (P = 1). POGO scores and the number of attempts also did not differ between DL and VL. In our simulated setting, just-in-time VL training provided similar intubation outcomes compared with DL in ETI performed by neonatal nurses. Just-in-time VL education may be an alternative to traditional DL for neonatal intubations.

  20. Transfusion transmitted infections in thalassaemics: need for reappraisal of blood screening strategy in India.

    PubMed

    Shyamala, V

    2014-04-01

    The aim of the study was to assess the blood safety in India through prevalence in thalassaemic population. Safety of the blood supply is a subject of great concern for all recipients. This review attempts to assess the relevance and format of tests for viruses in the context of transfusion transmitted infection (TTI) prevalence in India. Serological marker testing for human immunodeficiency virus-1/2 (HIV-1/2), hepatitis C virus (HCV) and hepatitis B virus (HBV) is mandatory in India. Numerous TTI incidents in the repeat recipients supported by results from nucleic acid technology (NAT) testing indicate the deficiencies in blood safety. The β-thalassaemic population (3-17%) in India has been used to reflect on blood safety. The prevalence of HIV-1/2, HCV and HBV in the Indian donor population, the limitations in accessing safe donors, quality of serological tests and the impact on repeat recipients is evaluated. The reports point to prevalence of ˜2% of viral diseases in the blood donor population, and the insufficiency of serology testing resulting in up to 45% TTIs in thalassaemics. The revelation by individual donation (ID) NAT testing, of 1 per 310 units being serology negative-NAT reactive is alarming. Extrapolating the serology negative NAT reactive yields, for an annual blood supply of 7.9 million units, 23,700 units or nearly 100,000 blood components are likely to be infectious. Though the cost for ID-NAT testing is considered unaffordable for a medium development country such as India, the enormity of TTIs will place an unmanageable cost burden on the society.

  1. The unique roles of intrapersonal and social factors in adolescent smoking development.

    PubMed

    Defoe, Ivy N; Semon Dubas, Judith; Somerville, Leah H; Lugtig, Peter; van Aken, Marcel A G

    2016-12-01

    Adolescence is a vulnerable period for the initiation and peak of many harmful risk-taking behaviors such as smoking, which is among the most addictive and deadliest behaviors. Generic metatheories like the theory of triadic influence (TTI) suggest that interrelated risk factors across multiple domains (i.e., intrapersonal and social/environmental) jointly contribute to adolescent smoking behavior. Yet, studies are lacking that investigate risk factors across different domains in the same study, which obscures whether each makes a unique contribution to the increase in smoking throughout adolescence or whether there is overlap across the domains. Hence, to fill this gap using a latent growth approach, the current accelerated longitudinal study investigated the collective contribution of multiple intrapersonal and social risk factors in the development of smoking behavior from ages 12 to 17 in 574 ethnically diverse Dutch adolescents. Results from the latent growth model showed that whereas the contribution of motivational-intrapersonal factors like sensation-seeking was no longer significant in the stringent multivariate model, higher levels of impulsivity (cognitive-intrapersonal) and overt peer pressure (social) at age 12 proved to be robust and unique predictors of linear increases in adolescent smoking up until age 17. Consistent with the TTI, adolescent smoking progression does not occur in isolation and the determinants are wide-ranging as they stem from both intrapersonal and social domains. Thus focusing on such confluence of intrapersonal and social risk factors via prevention programs from as young as age 12 might halt the deadly increase in smoking behavior throughout adolescence. (PsycINFO Database Record

  2. Blood pressure and heart rate responses to sudden changes of gravity during exercise.

    PubMed

    Linnarsson, D; Sundberg, C J; Tedner, B; Haruna, Y; Karemaker, J M; Antonutto, G; Di Prampero, P E

    1996-06-01

    Heart rate (HR) and blood pressure responses to sudden changes of gravity during 80- to 100-W leg exercise were studied. One group was exposed to sudden changes between 1.0 and 0 g in the head-to-foot direction (Gz+), starting upright and with repeated 30-s tilts to the supine position. Another group was exposed to sudden Gz+ changes between 1.8 and 0 g in an aircraft performing parabolic flight. Arterial blood pressure at the level of the carotid (carotid distending pressure, CDP) showed a large transient increase by 27-47 mmHg when Gz+ was suddenly decreased and a similar drop when Gz+ was suddenly increased. HR displayed a reverse pattern with larger transients (-22 to -26 min-1) in response to Gz+ decreases and more sluggish changes of lower amplitude in the other direction. Central blood volume, as estimated from the inverse of transthoracic impedance (1/TTI), varied in concert with Gz+. A model is proposed in which HR responses are described as a function of CDP and 1/TTI after a time delay of 2.3-3.0 s and including a low-pass filter function with time constants of 0.34-0.35 s for decreasing HR and time constants of 2.9-4.6 s for increasing HR. The sensitivity of the carotid component was around -0.8 to -1.0 min-1 . mmHg-1 (4-7 ms/mmHg). The cardiopulmonary baroreceptor component was an additive input but was of modest relative importance during the initial HR responses. For steady-state HR responses, however, our model suggests that inputs from carotid and cardiopulmonary receptors are of equal importance.

  3. Contribution of central versus sweat gland mechanisms to the seasonal change of sweating function in young sedentary males and females

    NASA Astrophysics Data System (ADS)

    Taniguchi, Yumiko; Sugenoya, Junichi; Nishimura, Naoki; Iwase, Satoshi; Matsumoto, Takaaki; Shimizu, Yuuki; Inukai, Yoko; Sato, Maki

    2011-03-01

    In summer and winter, young, sedentary male ( N = 5) and female ( N = 7) subjects were exposed to heat in a climate chamber in which ambient temperature (Ta) was raised continuously from 30 to 42°C at a rate of 0.1°C min-1 at a relative humidity of 40%. Sweat rates (SR) were measured continuously on forearm, chest and forehead together with tympanic temperature (Tty), mean skin temperature ( {overline {{T}} {{s}}} ) and mean body temperature ( {overline {{T}} {{b}}} ) . The rate of sweat expulsions (Fsw) was obtained as an indicator of central sudomotor activity. Tty and ( {overline {{T}} {{b}}} ) were significantly lower during summer compared with winter in males; SR was not significantly different between summer and winter in males, but was significantly higher during summer in females; SR during winter was higher in males compared with females. The regression line relating Fsw to ( {overline {{T}} {{b}}} ) shifted significantly from winter to summer in males and females, but the magnitude of the shift was not significantly different between the two subject groups. The regression line relating SR to Fsw was steepened significantly from winter to summer in males and females, and the change in the slope was significantly greater in females than in males. Females showed a lower slope in winter and a similar slope in summer compared to males. It was concluded that sweating function was improved during summer mediated by central sudomotor and sweat gland mechanisms in males and females, and, although the change of sweat gland function from winter to summer was greater in females as compared with males, the level of increased sweat gland function during summer was similar between the two subject groups.

  4. Effect of cyclical thermal to mechanical properties of Hybrid Laminate Composites (HLC) with skin recycle polypropylene/natural fiber/halloysite and core PP/KF composites

    NASA Astrophysics Data System (ADS)

    Sri Suharty, Neng; Ismail, Hanafi; Suci Handayani, Desi; Diharjo, Kuncoro; Rachman Wibowo, Fajar; Arnita Wuri, Margaretha

    2016-02-01

    This research has successfully synthesized six hybrid laminate composites (HLC). These HLC consist of two layers skin composites and one layer of core PP/KF composites. There are sticked with epoxy adhesive by using cold press method. In this research 6 types of skin are used, namely the rPP (recycled polypropylene, HC1); rPP/DVB/PP-g-AA/KF (HC2); rPP/DVB/PP-g-AA/Hall (HC3); rPP/DVB/PP-g-AA/Hall+ZB (HC4); rPP/DVB/PP-g-AA/KF/Hall (HC5) and rPP/DVB/PP-g-AA/KF/Hall+ZB (HC6) composites. The mechanical properties assessment tensile strength (TS) of various HLC before and after cyclical thermal (CT) was done by ASTM D638. While testing the flame retardant: such as time to ignition (TTI) and burning rate (BR) was done by ASTM D635. Heat stability of HLC can be recognized by conducting the CT treatment. It is to determine the effect of fluctuating heat loads on mechanical properties of HLC materials. The TS result of five HLCs (HC2, HC3, HC4, HC5 and HC6) before CT treatment were higher than HC1 (blank HLC). Those five HLC are also able to increase the TTI and reduce the BR compared to HC1. The CT treatment conditions performed at 45 oC as much as 125 times. After CT treatment, the TS values only slightly decline compared to before CT treatment.

  5. The acute effects of smokeless tobacco on central aortic blood pressure and wave reflection characteristics

    PubMed Central

    Martin, Jeffrey S; Beck, Darren T; Gurovich, Alvaro N; Braith, Randy W

    2010-01-01

    The main objectives of this study were to examine the acute effect of a single dose of smokeless tobacco (ST) on central aortic blood pressure and wave reflection characteristics. Fifteen apparently healthy male subjects (aged 30.6 ± 6.2 y) were given a 2.5 g oral dose of ST after baseline measurements were recorded. Pulse wave analysis using radial artery applanation tonometry was performed in triplicate at baseline (0 min) and at 10-min intervals during (10, 20 and 30 min) and after (40, 50 and 60 min) ST use. An acute dose of ST was associated with a significant increase in heart rate (HR), central aortic systolic and diastolic blood pressure, peripheral brachial systolic and diastolic blood pressure, and aortic augmentation index normalized to a fixed heart rate of 75 bpm (AIx@75). Furthermore, ejection duration and round trip travel time of the reflected pressure wave (Δtp) were significantly decreased as a result of one time ST use. As a result of changes in aortic pressure wave reflection characteristics, there was a significant increase in wasted left ventricular pressure energy (LVEw) and the tension–time index (TTI) as a result of ST use. In conclusion, one time use of ST elicits significant transient increases in HR, central aortic pressures, AIx@75, the TTI and LVEw. Chronic users subjected to decades of elevated central pressures and left ventricular work may have an increased cardiovascular risk as central aortic pressures are even more strongly related to cardiovascular outcomes than peripheral blood pressures. PMID:20719817

  6. The acute effects of smokeless tobacco on central aortic blood pressure and wave reflection characteristics.

    PubMed

    Martin, Jeffrey S; Beck, Darren T; Gurovich, Alvaro N; Braith, Randy W

    2010-10-01

    The main objectives of this study were to examine the acute effect of a single dose of smokeless tobacco (ST) on central aortic blood pressure and wave reflection characteristics. Fifteen apparently healthy male subjects (aged 30.6 ± 6.2 y) were given a 2.5 g oral dose of ST after baseline measurements were recorded. Pulse wave analysis using radial artery applanation tonometry was performed in triplicate at baseline (0 min) and at 10-min intervals during (10, 20 and 30 min) and after (40, 50 and 60 min) ST use. An acute dose of ST was associated with a significant increase in heart rate (HR), central aortic systolic and diastolic blood pressure, peripheral brachial systolic and diastolic blood pressure, and aortic augmentation index normalized to a fixed heart rate of 75 bpm (AIx@75). Furthermore, ejection duration and round trip travel time of the reflected pressure wave (Δt(p)) were significantly decreased as a result of one time ST use. As a result of changes in aortic pressure wave reflection characteristics, there was a significant increase in wasted left ventricular pressure energy (LVE(w)) and the tension-time index (TTI) as a result of ST use. In conclusion, one time use of ST elicits significant transient increases in HR, central aortic pressures, AIx@75, the TTI and LVE(w). Chronic users subjected to decades of elevated central pressures and left ventricular work may have an increased cardiovascular risk as central aortic pressures are even more strongly related to cardiovascular outcomes than peripheral blood pressures.

  7. Effects of series elastic compliance on muscle force summation and the rate of force rise.

    PubMed

    Mayfield, Dean L; Cresswell, Andrew G; Lichtwark, Glen A

    2016-10-15

    Compliant tendons permit mechanically unfavourable fascicle dynamics during fixed-end contractions. The purpose of this study was to reduce the effective compliance of tendon and investigate how small reductions in active shortening affect twitch kinetics and contractile performance in response to a second stimulus. The series elastic element (SEE) of the human triceps surae (N=15) was effectively stiffened by applying a 55 ms rotation to the ankle, through a range of 5 deg, at the onset of twitch and doublet [interstimulus interval (ISI) of 80 ms] stimulation. Ultrasonography was employed to quantify lateral gastrocnemius and soleus fascicle lengths. Rotation increased twitch torque (40-75%), rate of torque development (RTD; 124-154%) and torque-time integral (TTI; 70-110%) relative to constant-length contractions at the initial and final joint positions, yet caused only modest reductions in shortening amplitude and velocity. The torque contribution of the second pulse increased when stimulation was preceded by rotation, a finding unable to be explained on the basis of fascicle length or SEE stiffness during contraction post-rotation. A further increase in torque contribution was not demonstrated, nor was an increase in doublet TTI, when the second pulse was delivered during rotation and shortly after the initial pulse (ISI of 10 ms). The depressant effect of active shortening on subsequent torque generation suggests that compliant tendons, by affording large length changes, may limit torque summation. Our findings indicate that changes in tendon compliance shown to occur in response to resistance training or unloading are likely sufficient to considerably alter contractile performance, particularly maximal RTD.

  8. Zircon trace element geochemistry and growth of the Pleistocene to Holocene Mono Craters rhyolite magma system, California (USA)

    NASA Astrophysics Data System (ADS)

    Baker, N.; Miller, J. S.; Vazquez, J. A.; Marcaida, M.; Lidzbarski, M. I.

    2015-12-01

    The Mono Craters, part of the Mono-Inyo volcanic chain in eastern California, comprise at least 27 high-silica Pleistocene to Holocene rhyolite domes, lava flows and tephra cones. The Holocene chronology of the Mono Craters is well constrained but only recently has 238U-230Th zircon and 40Ar/39Ar dating elucidated the Pleistocene eruptive history. We performed trace element analysis on dated zircon crystal rims and sectioned interiors (using SHRIMP-RG) from 3 rhyolite domes (21, 12.5, and 7 ka) with additional rim data on 5 ashes separated from juvenile pumice clasts in the correlative Wilson Creek Formation (spanning from 62 to 21 ka). Ti-in-zircon (TTi,zrc) thermometry (titania activity from coexisting Fe-Ti oxides) gives temperatures predominantly between 650°C and 750°C, similar to average zircon saturation temperatures (Tzrc,sat). The observation that Tzrc,sat ≈ TTi,zrc indicates that Mono Craters rhyolite magmas were zircon-saturated and erupted at these temperatures (near water-saturated granite eutectic). Variations in key trace elements are relatively limited overall and zircons display similar REE patterns with generally curved MREE to HREE patterns and prominent negative Eu anomalies. Most of the variation is observed in zircons from older eruptions (62-41 ka). Zircon rims from Ash 17 of the Wilson Creek Formation (59 ka) have elevated Th/U, Eu/Eu*, and Ti and lower Hf compared to Ash 19 (62 ka), which suggests a thermal rejuvenation event between these two eruptions. Zircon rims from Ash 15 (41 ka) are characterized by a trend toward high Hf, at relatively low and relatively constant Ti, and low Eu/Eu*, consistent with rhyolite magma undergoing eutectic-like crystallization just prior to eruption. Zircon surfaces and interiors for the 21, 12.5, and 7 ka dome eruptions have very similar Hf, low Eu/Eu*, low Ti, and low Th/U. This requires zircon crystallization in a very uniform thermal and chemical environment from the latest Pleistocene to Holocene

  9. Red-light running violation prediction using observational and simulator data.

    PubMed

    Jahangiri, Arash; Rakha, Hesham; Dingus, Thomas A

    2016-11-01

    In the United States, 683 people were killed and an estimated 133,000 were injured in crashes due to running red lights in 2012. To help prevent/mitigate crashes caused by running red lights, these violations need to be identified before they occur, so both the road users (i.e., drivers, pedestrians, etc.) in potential danger and the infrastructure can be notified and actions can be taken accordingly. Two different data sets were used to assess the feasibility of developing red-light running (RLR) violation prediction models: (1) observational data and (2) driver simulator data. Both data sets included common factors, such as time to intersection (TTI), distance to intersection (DTI), and velocity at the onset of the yellow indication. However, the observational data set provided additional factors that the simulator data set did not, and vice versa. The observational data included vehicle information (e.g., speed, acceleration, etc.) for several different time frames. For each vehicle approaching an intersection in the observational data set, required data were extracted from several time frames as the vehicle drew closer to the intersection. However, since the observational data were inherently anonymous, driver factors such as age and gender were unavailable in the observational data set. Conversely, the simulator data set contained age and gender. In addition, the simulator data included a secondary (non-driving) task factor and a treatment factor (i.e., incoming/outgoing calls while driving). The simulator data only included vehicle information for certain time frames (e.g., yellow onset); the data did not provide vehicle information for several different time frames while vehicles were approaching an intersection. In this study, the random forest (RF) machine-learning technique was adopted to develop RLR violation prediction models. Factor importance was obtained for different models and different data sets to show how differently the factors influence the

  10. Tandem-ring dwell time ratio in Nigeria: dose comparisons of two loading patterns in standard high-dose-rate brachytherapy planning for cervical cancer

    PubMed Central

    Ibhade, Obed Rachel; Idayat, Akinlade Bidemi; Atara I., Ntekim

    2015-01-01

    Purpose In high-dose-rate (HDR) brachytherapy (BT), the source dwell times and dwell positions are essential treatment planning parameters. An optimal choice of these factors is fundamental to obtain the desired target coverage with the lowest achievable dose to the organs at risk (OARs). This study evaluates relevant dose parameters in cervix brachytherapy in order to assess existing tandem-ring dwell time ratio used at the first HDR BT center in Nigeria, and compare it with an alternative source loading pattern. Material and methods At the Radiotherapy Department, University College Hospital (UCH), Ibadan, Nigeria, a total of 370 standard treatment plans in two alternative sets were generated with HDR basic 2.6 software for one hundred and eighty five cervical cancer patients. The initial 185 individual plans were created for clinical treatment using the tandem-ring dwell time ratio of 1 : 1. Modifying the initial applicator loading ratio, the second set of plans with related dose data were also obtained for study purposes only. Total reference air kerma (TRAK), total time index (TTI), ICRU volume, treatment time, point B dose, ICRU bladder dose, and rectal points dose were evaluated for both sets of plans. Results The means of all evaluated dose parameters decreased when the existing tandem-ring dwell time ratio (1 : 1) was modified to other dwell weightings (1 : 1 – 3 : 1). These reductions were 13.43% (ICRU volume), 9.83% (rectal dose), 6.68% (point B dose), 6.08% (treatment time), 5.90% (TRAK), 5.88% (TTI), and 1.08% (bladder dose). Correspondingly, coefficients of variation changed by –7.98%, –5.02%, –5.23%, –4.20%, –3.93%, 8.65%, and 3.96% from the existing pattern to the alternative one. Conclusion Tandem-ring dwell time ratio has significant influence on dosimetric parameters. This study has indicated the need to modify the existing planning approach at UCH. PMID:26034498

  11. Verification of a two-dimensional infiltration model for the resin transfer molding process

    NASA Technical Reports Server (NTRS)

    Hammond, Vincent H.; Loos, Alfred C.; Dexter, H. Benson; Hasko, Gregory H.

    1993-01-01

    A two-dimensional finite element model for the infiltration of a dry textile preform by an injected resin was verified. The model, which is based on the finite element/control volume technique, determines the total infiltration time and the pressure increase at the mold inlet associated with the RTM process. Important input data for the model are the compaction and permeability behavior of the preform along with the kinetic and rheological behavior of the resin. The compaction behavior for several textile preforms was determined by experimental methods. A power law regression model was used to relate fiber volume fraction to the applied compaction pressure. Results showed a large increase in fiber volume fraction with the initial application of pressure. However, as the maximum fiber volume fraction was approached, the amount of compaction pressure required to decrease the porosity of the preform rapidly increased. Similarly, a power law regression model was used to relate permeability to the fiber volume fraction of the preform. Two methods were used to measure the permeability of the textile preform. The first, known as the steady state method, measures the permeability of a saturated preform under constant flow rate conditions. The second, denoted the advancing front method, determines the permeability of a dry preform to an infiltrating fluid. Water, corn oil, and an epoxy resin, Epon 815, were used to determine the effect of fluid type and viscosity on the steady state permeability behavior of the preform. Permeability values measured with the different fluids showed that fluid viscosity had no influence on the permeability behavior of 162 E-glass and TTI IM7/8HS preforms. Permeabilities measured from steady state and advancing front experiments for the warp direction of 162 E-glass fabric were similar. This behavior was noticed for tests conducted with corn oil and Epon 815. Comparable behavior was observed for the warp direction of the TTI IM7/8HS preform

  12. Determinants of Neonatal Mortality in North Shoa Zone, Amhara Regional State, Ethiopia

    PubMed Central

    Kolola, Tufa; Ekubay, Meseret; Tesfa, Endalamaw; Morka, Wogene

    2016-01-01

    In Ethiopia, neonatal mortality has been declined since the declaration of Millennium Developmental Goals, but the rate was slower since 2006. Thus, this study was designed to assess the determinants of neonatal mortality (NM) in North Shoa Zone. A community based case-control study was conducted on 84 cases and 252 controls. Cases were deceased new-borns within 28 days of birth while controls were infants survived beyond the first 28 days. Data were collected from mothers of the cases and controls using interviewer administered questionnaires. Multivariate analysis was done to examine determinants of NM. Variables significantly associated with NM in bivariate analysis were selected for multivariate analysis. Neonates whose mothers not attended antenatal care (AOR: 3.47; 95%CI: 1.44–8.32), delivered at home (AOR: 2.86; 95%CI: 1.56–5.26), and not received postnatal care services (AOR: 3.09; 95%CI: 1.73–5.51) were more likely to die. The odds of neonatal death was higher among neonates not breastfed within the first hour of delivery than those who breastfed within the first hour of delivery (AOR: 23.48; 95%CI: 8.43–65.37). Likewise, no-colostrum intake was positively associated with neonatal death. Neonates born to mothers who not received or received a single dose of tetanus toxoid injection (TTI) were more likely to experience death than those neonates born to mothers who received two or more doses of TTI (AOR: 2.05; 95%CI: 1.14–3.70). Furthermore, being small in size at birth (AOR: 2.66; 95%CI: 1.33–5.33) and male in sex (AOR: 1.85; 95% CI: 1.06–3.26) were risk factors for NM. In conclusion, neonatal mortality was significantly associated with factors that are modifiable through addressing the continuum-of-care approach in healthcare services in North Shoa. This implies that ensuring a continuity of health care services for maternal and new-borns from antenatal to postnatal care will improve neonatal survival. PMID:27741284

  13. Development of Side Impact Thoracic Injury Criteria and Their Application to the Modified ES-2 Dummy with Rib Extensions (ES-2re).

    PubMed

    Kuppa, Shashi; Eppinger, Rolf H; McKoy, Felicia; Nguyen, Thuvan; Pintar, Frank A; Yoganandan, Narayan

    2003-10-01

    Forty-two side impact cadaver sled tests were conducted at 24 and 32 km/h impact speeds into rigid and padded walls. The post-mortem human subjects were instrumented with accelerometers on the ribs and spine and chest bands around the thorax and abdomen to characterize their mechanical response during the impact. Load cells at the wall measured the impact force at the level of the thorax, abdomen, pelvis, and lower extremities. The resulting injuries were determined through detailed autopsy and radiography. Rib fractures with or without associated hemo/pneumo thorax or flail chest were the most common injury with severity ranging from AIS=0 to 5. Full and half thorax deflections were computed from the chest band data. The cadaver test data was analyzed using ANOVA and logistic regression. The age of the subject at the time of death had influence on injury outcome while gender and mass of the subject had little or no influence on injury outcome. Existing side impact injury criteria were evaluated such as Thoracic Trauma Index (TTI), Average Spinal Acceleration (ASA), full and half thorax deflections, chest velocity and viscous criterion, and contact force. The analysis results indicate that maximum normalized average half thorax deflection was the best predictor of AIS>/=3 and AIS>/=4 thoracic injury. TTI and upper spine accelerations were also good predictors of thoracic injury. Sixteen side impact sled tests were also conducted with the modified ES-2 dummy with rib extensions (ES-2re) under similar impact conditions as the cadaver tests. The rib extensions were added to the original ES-2 dummy ribs to prevent the "seat grabbing" action of the back plate that was noticed in some side impact vehicle crash tests with the ES-2 dummy. A separate analysis was conducted using the injury response and subject characteristics from the cadaver tests and the physical parameters derived from measurements on the ES-2re dummy in sled tests under similar conditions as the cadaver

  14. Seroprevalence of transfusion transmissible infections among blood donors at the blood bank of a Medical College of Kolkata.

    PubMed

    Karmakar, Prasanta Ray; Shrivastava, Prabha; Ray, Tapobrata Guha

    2014-01-01

    Seroprevalence of transfusion transmissible infections (TTIs) among blood donors can be used to monitor the prevalence among apparently healthy adult population. The present study was conducted to determine the profile of blood donors and seroprevalence of TTI among them. Retrospective analysis of the donors of a blood bank attached with a tertiary care hospital of Kolkata in 2011 was carried out. Data were analyzed with SPSS version 17. Majority (85%) of the donors were male, two-third in the age group of 21-40 years. Among the donors 2.79% were positive for any of the screened TTIs. Seroprevalence was highest for hepatitis B (1.41%) followed by human immunodeficiency virus (0.60%) and hepatitis C (0.59%) and least for syphilis (0.23%). Seropositivity increased with age up to 50 years. There was no significant difference in seropositivity between male and female. Highly sensitive donor screening and public awareness program can make transfusion of blood products safe.

  15. Epidemiology of Transfusion Transmitted Infection among Patients with β-Thalassaemia Major in Pakistan

    PubMed Central

    Ahmed Kiani, Rizwan; Anwar, Muhammad; Asad, Muhammad Javaid; Abbasi, Saleem; Abbas Zaheer, Hasan

    2016-01-01

    Introduction. Transfusion Transmitted Infections (TTIs) continue to be a major risk in transfusions in many parts of the world. The transfusion-dependent β-thalassaemia patients are particularly at risk of acquiring TTIs. The current study was undertaken to estimate the prevalence of TTIs in transfusion-dependent β-thalassaemia patients. Material and Methods. A cross-sectional study of 1253 multitransfused thalassaemia major patients was conducted in five different centres of Islamabad, Rawalpindi, and Karachi. The study subjects were screened for HIV, HCV, and HBV. The screening was performed at two centres: Department of Pathology, Shaheed Zulfiqar Ali Bhutto (SZAB) Medical University, and Blood Transfusion Services, Jinnah Postgraduate Medical Centre, from July to December 2015. The confirmatory screening was performed by Chemiluminescent Immunoassay (CLIA). Results. Out of the 1253 multiple transfused patients, 317 (25.3%) were infected with TTIs. HCV was positive in 273 cases (21.7%), HBV in 38 cases (3.0%), and HIV in 6 cases (0.5%). Conclusion. HCV was the leading TTI in multitransfused thalassaemia major patients in the study. Presence of HIV in thalassaemia patients is a recent disturbing development in Pakistan. Improved regulation of blood banks including use of internationally or nationally evaluated kits will bring down the incidence of TTIs in transfusion-dependent β-thalassaemia patients. More stringent behavioral and serological pretransfusion screening of blood for TTIs must be implemented in blood banks. PMID:27559490

  16. Properties of Wheat-Straw Boards with Frw Based on Interface Treatment

    NASA Astrophysics Data System (ADS)

    Zhu, X. D.; Wang, F. H.; Liu, Y.

    This paper explored the effect of MDI, UF and FRW content on the mechanical and fire retardant property of straw based panels with surface alkali liquor processing. In order to manufacture the straw based panel with high quality, low toxic and fire retardant, the interface of wheat-straw was treated with alkaline liquid, and the orthogonal test was carried out to optimize the technical parameters. The conductivity and diffusion coefficient K of the straw material after alkaline liquid treatment increased obviously. This indicated that alkaline liquid treatment improved the surface wet ability of straw, which is helpful for the infiltration of resin. The results of orthogonal test showed that the optimized treating condition was alkaline liquid concentration as 0.4-0.8%, alkaline dosage as 1:2.5-1:4.5, alkalinetreated time as 12h-48 h.The physical and mechanical properties of wheat-straw boards after treated increased remarkably and it could satisfy the national standard. The improvement of the straw surface wet ability is helpful to the forming of chemical bond. Whereas the variance analysis of the fire retardant property of straw based panel showed that TTI, pkHRR and peak value appearance time were not affected by the MDI, UF and FRW content significantly. The results of orthogonal test showed that the optimized processing condition was MDI content as 3%, UF resin content as 6% and the FRW content as 10%.

  17. Lagrangian modelling of OPALE dataset.

    NASA Astrophysics Data System (ADS)

    Gil, Jaime E.; Thomas, Jennie; Bekki, Slimane; Kukui, Alexandre; Ancellet, Gerad; Preunkert, Susanne; Legrand, Michel; Frey, Markus; Savarino, Joel; Jourdain, Bruno; Kerbrat, Michel; France, James; King, Martin; Toumi, Ralf

    2013-04-01

    The OPALE measurement campaign aimed to characterize the atmospheric chemistry of the East Antarctic Plateau making a range of measurements at two sites, a coastal one, Dumont d'Urville (DDU) (From December 2010 until March 2011, 66o S, 123oE, coastal site) and on top of the Antarctic plateau Dome C (From December 2011 until January 2012 at Dome C, 75oS, 123o E, 3233 m a.s.l.). There are relatively few observations of chemistry occurring inland and coastal sites Antarctic sites. During the campaign air masses originating from the marine boundary layer, the free troposphere, the Antarctic continent, and of mixed origins were observed. We present analyses of chemical measurements (including O3, NO2, OH, RO2, hydrocarbons) using the CiTTyCAT photochemical trajectory model. The model simulates the chemistry of air masses over multiple (~5) days back trajectories provided by a stochastic trajectory model (FLEXPART). In some cases, the initial chemical conditions are taken from a chemistry-transport model (MOZART). The effect of clouds on the photolysis rates is also accounted for using MODIS satellite data. The model results are compared with measurements performed during both OPALE campaign years. Differences between the reactive nitrogen and hydroxyl radical chemistry at DDU and Dome C and the strong influence of reactive exchanges of trace gases between the snow and the atmosphere at Dome C are highlighted. The implications for the oxidizing capacity of the Antarctic boundary layer are also discussed.

  18. Production of scandium-44m and scandium-44g with deuterons on calcium-44: cross section measurements and production yield calculations

    NASA Astrophysics Data System (ADS)

    Duchemin, C.; Guertin, A.; Haddad, F.; Michel, N.; Métivier, V.

    2015-09-01

    HIGHLIGHTS • Production of Sc-44m, Sc-44g and contaminants. • Experimental values determined using the stacked-foil technique. • Thick-Target production Yield (TTY) calculations. • Comparison with the TALYS code version 1.6. Among the large number of radionuclides of medical interest, Sc-44 is promising for PET imaging. Either the ground-state Sc-44g or the metastable-state Sc-44m can be used for such applications, depending on the molecule used as vector. This study compares the production rates of both Sc-44 states, when protons or deuterons are used as projectiles on an enriched Calcium-44 target. This work presents the first set of data for the deuteron route. The results are compared with the TALYS code. The Thick-Target production Yields of Sc-44m and Sc-44g are calculated and compared with those for the proton route for three different scenarios: the production of Sc-44g for conventional PET imaging, its production for the new 3 γ imaging technique developed at the SUBATECH laboratory and the production of a Sc-44m/Sc-44g in vivo generator for antibody labelling.

  19. Effect of cationic surfactants on characteristics and colorimetric behavior of polydiacetylene/silica nanocomposite as time-temperature indicator

    NASA Astrophysics Data System (ADS)

    Nopwinyuwong, Atchareeya; Kitaoka, Takuya; Boonsupthip, Waraporn; Pechyen, Chiravoot; Suppakul, Panuwat

    2014-09-01

    Polydiacetylene (PDA)/silica nanocomposites were synthesized by self-assembly method using polymerizable amphiphilic diacetylene monomers, 10,12-pentacosadiynoic acid (PCDA). Addition of cationic surfactants (PDADMAC and CTAB) to PDA/SiO2 nanocomposites induced higher intermolecular force which affected their size, shape and color transition. Pure PDA, PDA/SiO2, PDA/SiO2/PDADMAC and PDA/SiO2/CTAB were investigated by particle size analysis, TEM, SEM, UV-vis spectroscopy and FT-IR. It was found that the PDA/SiO2 nanocomposites exhibited slightly larger particle sizes than those of other samples. The PDA/SiO2 nanocomposites with a core-shell structure were almost regarded as spherical-shaped particles. Cationic surfactants, especially CTAB, presumably affected the particle size and shape of PDA/SiO2 nanocomposites due to the disruption of hydrogen bonding between PDA head group and ammonium group. The colorimetric response of both PDA/SiO2/surfactant and surfactant-free PDA/SiO2 aqueous solutions directly changed in relation to time and temperature; thus they were expected to be applied as a new polymer-based time-temperature indicator (TTI).

  20. Performance indicators: A tool for continuous quality improvement

    PubMed Central

    Bhatnagar, Nidhi M; Soni, Shital; Gajjar, Maitrey; Shah, Mamta; Shah, Sangita; Patel, Vaidehi

    2016-01-01

    Background: Performance monitoring is an important tool which can be used for setting priorities for process improvement. At our centre, we have been monitoring every step in the processes, right from inventory of consumables (both critical and routine) to number of donors reactive for TTI. We conducted a study to measure the impact of monitoring Performance Indicators and how it could be used as a tool for Continuous Quality Improvement (CQI). Materials and Methods: The present study was a retrospective study where the performance indicator (PI) data of blood bank was analyzed for over four years. For certain parameters, benchmarks or thresholds were set that represented warning limits or action limits. The yearly data were collated from monthly data. Shifts or Trends, if any, were identified and Corrective and Preventive Action (CAPA) taken accordingly. At the end, outcomes of the analysis were charted. Results: After the yearly data evaluation, outcomes obtained were used to plan, correct and amend processes and systems in the blood center. It was observed that the workload of the center showed an upward trend. This helped us to plan for the purchase of consumables and management of manpower. The monitoring of usage and discard of blood helped in the efficient management of blood stocks. The need for any new equipment could also be judged by the trends in workload. Conclusion: Performance indicators are indispensible tools which various stakeholders in the Blood Transfusion centres should implement to improve on quality performance. PMID:27011669

  1. Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome.

    PubMed

    Glatter, Timo; Schittenhelm, Ralf B; Rinner, Oliver; Roguska, Katarzyna; Wepf, Alexander; Jünger, Martin A; Köhler, Katja; Jevtov, Irena; Choi, Hyungwon; Schmidt, Alexander; Nesvizhskii, Alexey I; Stocker, Hugo; Hafen, Ernst; Aebersold, Ruedi; Gstaiger, Matthias

    2011-11-08

    Genetic analysis in Drosophila melanogaster has been widely used to identify a system of genes that control cell growth in response to insulin and nutrients. Many of these genes encode components of the insulin receptor/target of rapamycin (InR/TOR) pathway. However, the biochemical context of this regulatory system is still poorly characterized in Drosophila. Here, we present the first quantitative study that systematically characterizes the modularity and hormone sensitivity of the interaction proteome underlying growth control by the dInR/TOR pathway. Applying quantitative affinity purification and mass spectrometry, we identified 97 high confidence protein interactions among 58 network components. In all, 22% of the detected interactions were regulated by insulin affecting membrane proximal as well as intracellular signaling complexes. Systematic functional analysis linked a subset of network components to the control of dTORC1 and dTORC2 activity. Furthermore, our data suggest the presence of three distinct dTOR kinase complexes, including the evolutionary conserved dTTT complex (Drosophila TOR, TELO2, TTI1). Subsequent genetic studies in flies suggest a role for dTTT in controlling cell growth via a dTORC1- and dTORC2-dependent mechanism.

  2. Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome

    PubMed Central

    Glatter, Timo; Schittenhelm, Ralf B; Rinner, Oliver; Roguska, Katarzyna; Wepf, Alexander; Jünger, Martin A; Köhler, Katja; Jevtov, Irena; Choi, Hyungwon; Schmidt, Alexander; Nesvizhskii, Alexey I; Stocker, Hugo; Hafen, Ernst; Aebersold, Ruedi; Gstaiger, Matthias

    2011-01-01

    Genetic analysis in Drosophila melanogaster has been widely used to identify a system of genes that control cell growth in response to insulin and nutrients. Many of these genes encode components of the insulin receptor/target of rapamycin (InR/TOR) pathway. However, the biochemical context of this regulatory system is still poorly characterized in Drosophila. Here, we present the first quantitative study that systematically characterizes the modularity and hormone sensitivity of the interaction proteome underlying growth control by the dInR/TOR pathway. Applying quantitative affinity purification and mass spectrometry, we identified 97 high confidence protein interactions among 58 network components. In all, 22% of the detected interactions were regulated by insulin affecting membrane proximal as well as intracellular signaling complexes. Systematic functional analysis linked a subset of network components to the control of dTORC1 and dTORC2 activity. Furthermore, our data suggest the presence of three distinct dTOR kinase complexes, including the evolutionary conserved dTTT complex (Drosophila TOR, TELO2, TTI1). Subsequent genetic studies in flies suggest a role for dTTT in controlling cell growth via a dTORC1- and dTORC2-dependent mechanism. PMID:22068330

  3. STS-96 crew takes part in payload Interface Verification Test

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the SPACEHAB Facility, STS-96 Mission Specialist Valery Tokarev of Russia (left) and Commander Kent Rominger (second from right) listen to Lynn Ashby (far right), with JSC, talking about the SPACEHAB equipment in front of them during a payload Interface Verification Test (IVT). In the background behind Tokarev is TTI interpreter Valentina Maydell. Other STS-96 crew members at KSC for the IVT are Pilot Rick Husband and Mission Specialists Dan Barry, Ellen Ochoa, Tamara Jernigan and Julie Payette. Mission STS-96 carries the SPACEHAB Logistics Double Module, which will have equipment to further outfit the International Space Station service module and equipment that can be off-loaded from the early U.S. assembly flights. It carries internal logistics and resupply cargo for station outfitting, plus an external Russian cargo crane to be mounted to the exterior of the Russian station segment and used to perform space walking maintenance activities. The double module stowage provides capacity of up to 10,000 lbs. with the ability to accommodate powered payloads, four external rooftop stowage locations, four double-rack locations (two powered), up to 61 bulkhead-mounted middeck locker locations, and floor storage for large unique items and Soft Stowage. STS-96 is targeted to launch May 20 about 9:32 a.m.

  4. STS-96 crew takes part in payload Interface Verification Test

    NASA Technical Reports Server (NTRS)

    1999-01-01

    In the SPACEHAB Facility, the STS-96 crew looks at equipment as part of a payload Interface Verification Test (IVT) for their upcoming mission to the International Space Station . From left are Mission Specialist Ellen Ochoa (behind the opened storage cover ), Commander Kent Rominger, Pilot Rick Husband (holding a lithium hydroxide canister) and Mission Specialists Dan Barry, Valery Tokarev of Russia and Julie Payette. In the background is TTI interpreter Valentina Maydell. The other crew member at KSC for the IVT is Mission Specialist Tamara Jernigan. Mission STS-96 carries the SPACEHAB Logistics Double Module, which has equipment to further outfit the International Space Station service module and equipment that can be off-loaded from the early U.S. assembly flights. The SPACEHAB carries internal logistics and resupply cargo for station outfitting, plus an external Russian cargo crane to be mounted to the exterior of the Russian station segment and used to perform space walking maintenance activities. The double module stowage provides capacity of up to 10,000 lbs. with the ability to accommodate powered payloads, four external rooftop stowage locations, four double-rack locations (two powered), up to 61 bulkhead-mounted middeck locker locations, and floor storage for large unique items and Soft Stowage. STS-96 is targeted to launch May 20 about 9:32 a.m.

  5. STS-96 crew takes part in payload Interface Verification Test

    NASA Technical Reports Server (NTRS)

    1999-01-01

    During a payload Interface Verification Test (IVT) in the SPACEHAB Facility, STS-96 Mission Specialist Valery Tokarev of Russia (second from left) and Commander Kent Rominger learn about the Sequential Shunt Unit (SSU) in front of them from Lynn Ashby (far right), with Johnson Space Center. At the far left looking on is TTI interpreter Valentina Maydell. Other crew members at KSC for the IVT are Pilot Rick Husband and Mission Specialists Ellen Ochoa, Tamara Jernigan, Dan Barry and Julie Payette. The SSU is part of the cargo on Mission STS-96, which carries the SPACEHAB Logistics Double Module, with equipment to further outfit the International Space Station service module and equipment that can be off-loaded from the early U.S. assembly flights. The SPACEHAB carries internal logistics and resupply cargo for station outfitting, plus an external Russian cargo crane to be mounted to the exterior of the Russian station segment and used to perform space walking maintenance activities. The double module stowage provides capacity of up to 10,000 lbs. with the ability to accommodate powered payloads, four external rooftop stowage locations, four double-rack locations (two powered), up to 61 bulkhead-mounted middeck locker locations, and floor storage for large unique items and Soft Stowage. STS-96 is targeted to launch May 20 about 9:32 a.m.

  6. Thermal modeling in Ceuta, Maracaibo Basin, Venezuela

    SciTech Connect

    Marcano, F.; Padron, S. )

    1993-02-01

    Hydrocarbon generation from Upper Cretaceous source rocks (Fm.La Luna) in Ceuta, center-eastern Maracaibo lake area in Venezuela, is modeled here, using a kinetic method and the conventional Time-Temperature Index (TTI) procedure. Geological evolution, burial and erosional history is based on available interpretation of 3D seismic and well data. Fragmentary present-day subsurface temperature data comes from corrected measurements in a few wells. Paleogradient/heat paleoflux was estimated during the thermal modeling on wells, by calculating vitrinite reflectances (Ro) or Tmax values and then comparing them with measured ones. However, thermal-indicator data does not always appear to be consistent and some data had to be rejected. Paleogradient evolution in the Cretaceous is controlled by the development of a isolated thermal compartment related to overpressures in a thick shaly sequence in the Upper Cretaceous. A geological section was studied in detail to illustrate possible migration paths to known fields and undrilled traps. Results show a good fit between the thermal evolution of the source rock and the maturity of the crude produced in the area.

  7. Purpura fulminans as clinical manifestation of atypical SLE with antiphospholipid antibodies: a case report.

    PubMed

    Gamba, G; Montani, N; Montecucco, C M; Caporali, R; Ascari, E

    1991-01-01

    Purpura Fulminans and DIC were the main clinical manifestations of the antiphospholipid syndrome observed in a 62-year-old man. The patient was well until 44 years of age when he began to suffer from recurrent thrombophlebitis, without other symptoms suggestive of immune disease. At the time of hospital admission the pt. appeared acutely ill, showing high fever, severe anemia, massive urinary blood loss, multiple purpuric patches evolving to hemorrhagic bullae and gangrene rapidly spreading over about 30% of the total body area. No signs of neurological involvement or of visceral thrombotic occlusions were present. Clotting tests were consistent with a diagnosis of DIC, further confirmed by skin biopsy showing the presence of thrombi in dermal arterioles. The autoantibody research was positive as follows: Waaler-Rose 1:40, Anti-DNA 1:80; ANF 1:640, aCA IgG 100 GPL. LA was diagnosed according to standard criteria: prolonged KCT and RVVT not corrected by a mixture of normal plasma and abnormal TTI. Plasma exchange in association with heparin and prednisone was effective in arresting the progression of the skin lesion; nevertheless the patient died ten days after hospital admission for sepsi and acute renal failure.

  8. Genome-Wide Identification of Mitogen-Activated Protein Kinase Gene Family across Fungal Lineage Shows Presence of Novel and Diverse Activation Loop Motifs

    PubMed Central

    Mohanta, Tapan Kumar; Mohanta, Nibedita; Parida, Pratap; Panda, Sujogya Kumar; Ponpandian, Lakshmi Narayanan; Bae, Hanhong

    2016-01-01

    The mitogen-activated protein kinase (MAPK) is characterized by the presence of the T-E-Y, T-D-Y, and T-G-Y motifs in its activation loop region and plays a significant role in regulating diverse cellular responses in eukaryotic organisms. Availability of large-scale genome data in the fungal kingdom encouraged us to identify and analyse the fungal MAPK gene family consisting of 173 fungal species. The analysis of the MAPK gene family resulted in the discovery of several novel activation loop motifs (T-T-Y, T-I-Y, T-N-Y, T-H-Y, T-S-Y, K-G-Y, T-Q-Y, S-E-Y and S-D-Y) in fungal MAPKs. The phylogenetic analysis suggests that fungal MAPKs are non-polymorphic, had evolved from their common ancestors around 1500 million years ago, and are distantly related to plant MAPKs. We are the first to report the presence of nine novel activation loop motifs in fungal MAPKs. The specificity of the activation loop motif plays a significant role in controlling different growth and stress related pathways in fungi. Hence, the presences of these nine novel activation loop motifs in fungi are of special interest. PMID:26918378

  9. Factors in enhancing blood safety by nucleic acid technology testing for human immunodeficiency virus, hepatitis C virus and hepatitis B virus

    PubMed Central

    Shyamala, Venkatakrishna

    2014-01-01

    In the last few decades through an awareness of transfusion transmitted infections (TTI), a majority of countries have mandated serology based blood screening assays for Human immunodeficiency virus (HIV), Hepatitis C virus (HCV), and Hepatitis B virus (HBV). However, despite improved serology assays, the transfusion transmission of HIV, HCV, and HBV continues, primarily due to release of serology negative units that are infectious because of the window period (WP) and occult HBV infections (OBI). Effective mode of nucleic acid technology (NAT) testing of the viruses can be used to minimize the risk of TTIs. This review compiles the examples of NAT testing failures for all three viruses; analyzes the causes for failure, and the suggestions from retrospective studies to minimize such failures. The results suggest the safest path to be individual donation testing (ID) format for highest sensitivity, and detection of multiple regions for rapidly mutating and recombining viruses. The role of blood screening in the context of the donation and transfusion practices in India, the donor population, and the epidemiology is also discussed. World wide, as the public awareness of TTIs increases, as the recipient rights for safe blood are legally upheld, as the possibility to manage diseases such as hepatitis through expensive and prolonged treatment becomes accessible, and the societal responsibility to shoulder the health costs as in the case for HIV becomes routine, there is much to gain by preventing infections than treating diseases. PMID:24678167

  10. Bypass balloon pumping: a newly developed device for mechanical circulatory support in heart failure.

    PubMed

    Hoshino, M; Asakura, T; Yasuura, K; Ogawa, Y; Okamoto, H; Matsuura, A

    2003-02-01

    Various types of assist devices have been developed for severe heart failures. Among them, intra-aortic balloon pumping (IABP) has achieved popularity, mainly in the treatment of patients with either severe cardiac infarction or low cardiac output syndrome (LOS) after open-heart surgery. However, IABP has a limitation in that although it acts as a pressure support, it cannot directly support flow volume. In cases of severe pump failure, stronger pump support would be required. However, there is a limit in the clinical use of temporary mechanical support using a pump because of the costs of the expensive equipment. With this in mind, we came up with a new idea in which the motion of a balloon in IABP system is converted into a power source for creating a one-way stream. In order to realize our idea, we made a J-shaped sample model of pulsating chamber incorporating two ball valves. In the hydrodynamic experiment using our new device, flows over 2500 ml/min (Max. 3475 ml/min) were obtained. The percent changes in parameters such as TTI, DPTI and bypass flows obtained by the experiment of left ventricular bypass have demonstrated that our assist system is effective for reducing cardiac work.

  11. Railroad system of Texas: A component of the state and national transportation infrastructure. Research report, September 1996--November 1998

    SciTech Connect

    Roop, S.S.; Warner, J.E.; Rosa, D.; Dickinson, R.W.

    1998-11-01

    Railroads continue to play an important role in the Texas transportation system. This study addresses the potential for implementing a rail planning process in the Texas Department of Transportation. The study is documented in three reports, produced in coordinated and parallel efforts by the Center for Transportation Research and the Texas Transportation Institute. This report documents the work performed by TTI, whereby a rail planning framework is presented which formalizes the planning process and presents the key elements as a series of discrete and logical steps. These steps may be used to guide TxDOT in the formation of goals, identification of issues and affected parties, selection of appropriate analytical methodologies, location of data sources, and implementation of results. The report also presents an in-depth discussion of several key issues facing transportation agencies. These include rail line abandonment, intermodal service planning, and urban rail rationalization. A discussion of the Texas rail system covers the Class 1 railroads, shortline railroads, Amtrak, and the Mexican rail system.

  12. Effect of silanized-chitosan on flammability, mechanical, water absorption and biodegradability properties of pseudo-stem banana fiber and montmorillonite filled waste polypropylene biocomposite

    NASA Astrophysics Data System (ADS)

    Prasetyo, W. E.; Prihandoko, A.; Pujiasih, S.; Widianto, A.; Rahmawati, N.; Saputra, O. A.; Handayani, D. S.

    2017-02-01

    Growing consciousness for an eco-friendly environment has revived the interest to develop composite fibers from biobased products. In this study, flammability, mechanical, water absorption and biodegradability properties of chitosan filled biocomposite waste polypropylene (wPP) reinforced with pseudo-stem banana fiber (PBF) and montmorillonite (MMt) biocomposites has been conducted investigate. It was successfully processed in solution method. Chitosan was chemically treated with glycidyloxypropyltrimethoxysilane (GPTMS) to improve interfacial adhesion between chitosan and wPP. The chitosan treated with GPTMS content in the biocomposites were varied from 0 to 7% (dry wt. basis). Flammability, tensile strength and water absorption index of biocomposites were measured according to ASTM D635, ASTM D638, and ASTM D570 respectively. To study the nature of its biodegradability, the biocomposites were technically buried in garbage dump land. The results show that the addition of treated chitosan 3-GPTMS has improved thermal properties such as Time to Ignition (TTi), Burning Rate (BR), and Heat release (HR) of treated biocomposites compared with neat PP and untreated biocomposite with treated chitosan. The treated biocomposites exhibit higher tensile strength and Young’s modulus, but lower elongation at break compared with neat PP and untreated biocomposites with treated chitosan. The biocomposites show a reduction in the rate of water uptake with higher loading of CH.

  13. Highly Efficient Flame Retardant Polyurethane Foam with Alginate/Clay Aerogel Coating.

    PubMed

    Chen, Hong-Bing; Shen, Peng; Chen, Ming-Jun; Zhao, Hai-Bo; Schiraldi, David A

    2016-11-30

    Highly efficient flame retardant polyurethane foams with alginate/clay aerogel coatings were fabricated using a freeze-drying method. The microstructure and the interaction of the samples were characterized with scanning electron and optical microscopy (SEM) and (OM). The results show that PU foam has a porous structure with pore sizes of several hundred microns, and that of aerogel ranges from 10 to 30 μm. The PU foam matrix and the aerogel coatings have strong interactions, due to the infusion of aerogel into the porous structure of the foam and the tension generated during the freeze-drying process. Both the PU foam and the aerogel exhibit good thermal stabilities, with onset decomposition temperatures above 240 °C. Combustion parameters, including LOI, TTI, HRR, TSR, FIGRA, CO, and CO2, all indicate significantly reduced fire risk. Total heat release of all but one of the samples was maintained, indicating that the flame retardant mechanism is to decrease flame spread rate by forming a heat, oxygen, and smoke barrier, rather than by reducing fuel content. This facile and inexpensive post-treatment of PU foam could expand its fire safe applications.

  14. Selective and low temperature transition metal intercalation in layered tellurides

    PubMed Central

    Yajima, Takeshi; Koshiko, Masaki; Zhang, Yaoqing; Oguchi, Tamio; Yu, Wen; Kato, Daichi; Kobayashi, Yoji; Orikasa, Yuki; Yamamoto, Takafumi; Uchimoto, Yoshiharu; Green, Mark A.; Kageyama, Hiroshi

    2016-01-01

    Layered materials embrace rich intercalation reactions to accommodate high concentrations of foreign species within their structures, and find many applications spanning from energy storage, ion exchange to secondary batteries. Light alkali metals are generally most easily intercalated due to their light mass, high charge/volume ratio and in many cases strong reducing properties. An evolving area of materials chemistry, however, is to capture metals selectively, which is of technological and environmental significance but rather unexplored. Here we show that the layered telluride T2PTe2 (T=Ti, Zr) displays exclusive insertion of transition metals (for example, Cd, Zn) as opposed to alkali cations, with tetrahedral coordination preference to tellurium. Interestingly, the intercalation reactions proceed in solid state and at surprisingly low temperatures (for example, 80 °C for cadmium in Ti2PTe2). The current method of controlling selectivity provides opportunities in the search for new materials for various applications that used to be possible only in a liquid. PMID:27966540

  15. Flame-retardant EPDM compounds containing phenanthrene to enhance radiation resistance

    NASA Astrophysics Data System (ADS)

    Chen, Jian; Huang, Wei; Jiang, Shu-Bin; Li, Xiao-Yan; An, You; Li, Chuang; Gao, Xiao-Ling; Chen, Hong-Bing

    2017-01-01

    Ethylene propylene diene monomer (EPDM) compounds with good flame-retardant and γ-ray radiation resistant properties were prepared by adding complex flame retardants and phenathrene. The resultant EPDM formulations have a long time to ignition (TTI >46 s), a low peak heat release rate (PHRR 341 kW/m2) and a high limited oxygen index (LOI >30). Effects of γ-ray radiation on the resultant flame-retardant EPDM was investigated. The formulated EPDM is a crosslinking dominated polymer under γ-ray radiation. The γ-ray radiation resistant property of EPDM was enhanced by adding phenanthrene. Elongation at break of EPDM formulated with phenanthrene could retain 91% after being irradiated to 0.3 MGy and still retains 40% elongation even after being irradiated to 0.9 MGy, which is much better the control. It is expected that the formulated flame-retardant and radiation resistant EPDM materials could meet the requirements for use in radiation environments.

  16. Thermal maturation and petroleum source rocks in Forest City and Salina basins, mid-continent, U. S. A

    SciTech Connect

    Newell, K.D.; Watney, W.L.; Hatch, J.R.; Xiaozhong, G.

    1986-05-01

    Shales in the Middle Ordovician Simpson Group are probably the source rocks for a geochemically distinct group of lower pristane and low phytane oils produced along the axis of the Forest City basin, a shallow cratonic Paleozoic basin. These oils, termed Ordovician-type oils, occur in some fields in the southern portion of the adjacent Salina basin. Maturation modeling by time-temperature index (TTI) calculations indicate that maturation of both basins was minimal during the early Paleozoic. The rate of maturation significantly increased during the Pennsylvanian because of rapid regional subsidence in response to the downwarping of the nearby Anadarko basin. When estimated thicknesses of eroded Pennsylvanian, Permian, and Cretaceous strata are considered, both basins remain relatively shallow, with maximum basement burial probably not exceeding 2 km. According to maturation modeling and regional structure mapping, the axes of both basins should contain Simpson rocks in the early stages of oil generation. The probability of finding commercial accumulations of Ordovician-type oil along the northwest-southeast trending axis of the Salina basin will decrease in a northwestward direction because of (1) westward thinning of the Simpson Group, and (2) lesser maturation due to lower geothermal gradients and shallower paleoburial depths. The optimum localities for finding fields of Ordovician-type oil in the southern Salina basin will be in down-plunge closures on anticlines that have drainage areas near the basin axis.

  17. Selective and low temperature transition metal intercalation in layered tellurides

    NASA Astrophysics Data System (ADS)

    Yajima, Takeshi; Koshiko, Masaki; Zhang, Yaoqing; Oguchi, Tamio; Yu, Wen; Kato, Daichi; Kobayashi, Yoji; Orikasa, Yuki; Yamamoto, Takafumi; Uchimoto, Yoshiharu; Green, Mark A.; Kageyama, Hiroshi

    2016-12-01

    Layered materials embrace rich intercalation reactions to accommodate high concentrations of foreign species within their structures, and find many applications spanning from energy storage, ion exchange to secondary batteries. Light alkali metals are generally most easily intercalated due to their light mass, high charge/volume ratio and in many cases strong reducing properties. An evolving area of materials chemistry, however, is to capture metals selectively, which is of technological and environmental significance but rather unexplored. Here we show that the layered telluride T2PTe2 (T=Ti, Zr) displays exclusive insertion of transition metals (for example, Cd, Zn) as opposed to alkali cations, with tetrahedral coordination preference to tellurium. Interestingly, the intercalation reactions proceed in solid state and at surprisingly low temperatures (for example, 80 °C for cadmium in Ti2PTe2). The current method of controlling selectivity provides opportunities in the search for new materials for various applications that used to be possible only in a liquid.

  18. Mapping spatial resources with GPS animal telemetry: foraging manatees locate seagrass beds in the Ten Thousand Islands, Florida, USA

    USGS Publications Warehouse

    Slone, Daniel H.; Reid, James P.; Kenworthy, W. Judson

    2013-01-01

    Turbid water conditions make the delineation and characterization of benthic habitats difficult by traditional in situ and remote sensing methods. Here, we develop and validate modeling and sampling methodology for detecting and characterizing seagrass beds by analyzing GPS telemetry records from radio-tagged manatees. Between October 2002 and October 2005, 14 manatees were tracked in the Ten Thousand Islands (TTI) in southwest Florida (USA) using Global Positioning System (GPS) tags. High density manatee use areas were found to occur off each island facing the open, nearshore waters of the Gulf of Mexico. We implemented a spatially stratified random sampling plan and used a camera-based sampling technique to observe and record bottom observations of seagrass and macroalgae presence and abundance. Five species of seagrass were identified in our study area: Halodule wrightii, Thalassia testudinum, Syringodium filiforme, Halophila engelmannii, and Halophila decipiens. A Bayesian model was developed to choose and parameterize a spatial process function that would describe the observed patterns of seagrass and macroalgae. The seagrasses were found in depths <2 m and in the higher manatee use strata, whereas macroalgae was found at moderate densities at all sampled depths and manatee use strata. The manatee spatial data showed a strong association with seagrass beds, a relationship that increased seagrass sampling efficiency. Our camera-based field sampling proved to be effective for assessing seagrass density and spatial coverage under turbid water conditions, and would be an effective monitoring tool to detect changes in seagrass beds.

  19. New insights into the North Taranaki Basin from New Zealand's first broadband 3D survey

    NASA Astrophysics Data System (ADS)

    Uzcategui, Marjosbet; Francis, Malcolm; Kong, Wai Tin Vincent; Patenall, Richard; Fell, Dominic; Paxton, Andrea; Allen, Tristan

    2016-06-01

    The Taranaki Basin is the only hydrocarbon producing basin in New Zealand. The North Taranaki Basin has widespread two-dimensional (2D) seismic coverage and numerous wells that have not encountered commercial accumulations. This is attributed to the structural complexity in the central graben and the absence of necessary information to help understand the basin's evolution. An active petroleum system has been confirmed by hydrocarbon shows and non-commercial oil and gas discoveries (Karewa-1 and Kora-1). A broadband long offset three-dimensional (3D) seismic survey was acquired and processed by Schlumberger in 2013 to evaluate the hydrocarbon potential of the North Taranaki Basin. Innovative acquisition techniques were combined with advanced processing and imaging methods. Raypath distortions and depth uncertainty were significantly reduced by processing through tilted transverse isotropy (TTI) anisotropic Kirchhoff prestack depth migration with a geologically constrained velocity model. The survey provided the necessary information to understand the petroleum system and provide evidence for material hydrocarbon accumulations. In this investigation, we assessed the hydrocarbon potential of the North Taranaki Basin using the newly acquired data. 3D seismic interpretation and amplitude-versus-offset (AVO) analysis support the renewed potential of the basin and demonstrate effectiveness of these technologies that together can achieve encouraging results for hydrocarbon exploration.

  20. Transfusion-Transmitted Malaria in Iran: A Narrative Review Article

    PubMed Central

    MARDANI, Ahmad; KESHAVARZ, Hossein; POURFATHOLLAH, Ali Akbar; MAGHSUDLU, Mahtab

    2016-01-01

    Background: Malaria is the most important transfusion-transmitted infection (TTI) in worldwide after viral hepatitis and human immunodeficiency virus (HIV) infection. The main objective of the present study was to review and evaluate the transmission of malaria via blood transfusion in Iran. Methods: A literature search was done without time limitation in the electronic databases as follows: PubMed, Scopus, Google Scholar, Web of Science, Science Direct, scientific information database (SID), Magiran, IranMedex and Irandoc. The searches were limited to the published papers to English and Persian languages. Results: Six papers were eligible. From 1963 to 1983, 344 cases of Transfusion-transmitted malaria (TTM) had been reported from different provinces of Iran. The most prevalent species of involved Plasmodium in investigated cases of TTM was Plasmodium malariae (79.24%). The screening results of 1,135 blood donors for malaria were negative by microscopic examination of peripheral blood smears and rapid diagnostic test (RDT) methods. Conclusion: Lack of TTM report from Iran in the last three decades indicates that the screening of blood donors through interviewing (donor selection) may be effective in the prevention of the occurrence of transfusion-transmitted malaria. PMID:28096847

  1. [The role of virological tests in the diagnosis of cytomegalovirus infection in pregnant women].

    PubMed

    Mihály, Ilona; Arányi, Zsuzsanna; Prinz, Gyula; Lukács, Adrienne; Kolozsi, Tímea; Liptai, Zoltán; Bábinszky, Agota; Kodaj, Imre; Petik, Dóra; Lázár, Gábor

    2014-10-12

    Bevezetés: A leggyakoribb magzatkárosító ágens a cytomegalovirus. A diagnosztika eszközeinek és a terápiás lehetőségeknek a fejlődése új perspektívát nyitott a terhességi cytomegalovirusfertőzések kiderítésében és kezelésében. Célkitűzés: A 2007 és 2012 közötti hat év terhességi cytomegalovirus szűrővizsgálati eredményeinek elemzése. Módszer: 956 várandós klinikai adatainak és virológiai eredményeinek retrospektív analízise. Eredmények: 65,4%-uk védett, 33,3%-uk fogékony volt cytomegalovirusfertőzés iránt. A szerzők 10 primer fertőzést igazoltak, három esetben kétes eredményt találtak. A 13 várandós közül hat tünetmentes, öt beteg, kettőnek magzati ultrahangeltérése volt. A négy követett terhes közül egy spontán elvetélt, kettő gyermekénél igazolódott, egynél kizárható volt a congenitalis fertőzés. Következtetések: A magyarországi terhességi cytomegalovirusátvészeltségi arány a magas higiénés viszonyokra jellemző. Klinikai gyanú esetén és enzimimmunoassay típusú vizsgálattal talált IgM-pozitív esetekben kötelező a konfirmációs vizsgálatok elvégzése. A szűrővizsgálatot a terhességvállalást megelőzően kellene beiktatni. Szükség van az érintett szakmák közötti szorosabb együttműködésre a kiszámíthatatlan szűrővizsgálati kérelmek szabályozása és az indokolatlan terhességmegszakítások megelőzése érdekében. Orv. Hetil., 2014, 155(41), 1632–1642.

  2. [Is ceCT necessary beyond FDG-PET/CT for primary staging in Hodgkin lymphoma?].

    PubMed

    Kajáry, Kornélia; Molnár, Zsuzsa; Szakáll, Szabolcs; Molnár, Péter; Lengyel, Zsolt

    2014-02-09

    Bevezetés: Nemzetközi tanulmányok igazolták, hogy Hodgkin-lymphoma kezelés előtti stádiummeghatározásában a natív, alacsony dózisú komputertomográfiával (CT) végzett, 18-F-fluorodeoxiglükóz (FDG) alkalmazásával készült pozitronemissziós tomográfia/komputertomográfia (standard PET/CT) pontosabb, mint az intravénás kontrasztanyag adásával végzett, normáldózisú CT-vizsgálat (konvencionális CT). Célkitűzés: A szerzők összehasonlították saját beteganyagukban a fenti indikációban külön-külön a két vizsgálat pontosságát, valamint megvizsgálták, hogy szükséges-e a standard PET/CT mellett konvencionális CT-vizsgálat elvégzése is. Módszer: Huszonnyolc beteg stádiumbesorolását végezték el a konvencionális CT-vizsgálat, majd a standard PET/CT vizsgálat alapján, végül a két vizsgálatot együttesen értékelték. Eredmények: Mindhárom módszerrel azonos stádiumot találtak 24 betegben. Négy betegnél a standard PET/CT-vel magasabb stádiumot észleltek, mint a konvencionális CT-vel. A csak standard PET/CT-vel meghatározott stádiumon nem változtatott a vizsgálatok együttes értékelése. Következtetések: A Hodgkin-lymphoma kezelés előtti stádiummeghatározásában a standard PET/CT vizsgálat pontosabb, mint az önállóan végzett konvencionális CT-vizsgálat. Emellett megállapítható, hogy ebben az indikációban nem indokolható a standard PET/CT konvencionális CT-vel való kiegészítése. Orv. Hetil., 2014, 155(6), 226–230.

  3. [Connection between cancer- and alcohol-related mortality in a rural practice of a South-Hungarian village].

    PubMed

    Péter, Arpád

    2013-05-05

    Bevezetés: A több mint negyedszázada ugyanazon egykörzetes községben dolgozó szerző az 1987 és 1999 közötti vizsgálati periódusban a daganatos halálozásnak az alkohollal kapcsolatos halálozással összefüggő hányadát férfiak körében 50%-nak, nők körében 7,9%-nak találta. Célkitűzés: A szerző célként tűzte ki a halálozás e két meghatározó tényezőjének hosszabb távú nyomon követéséhez és elemzéséhez a halálozási mutatók ismételt felmérését a 2000 és 2011 közötti időszakra vonatkozóan. Módszer: Az elhunyt betegek valamennyi fontos előzményi adatát összefoglaló háziorvosi halotti epikrízisekbe tömörítette és a halálokok kiválasztásakor ezeket döntő súllyal vette figyelembe. Eredmények: A vizsgált 12 év alatt a szerző úgynevezett „tisztított praxislakossága” körében 326 ember halt meg (167 férfi, 159 nő). Bár a részeredményeket tekintve is jelentős átstruktúrálódás következett be a daganatos és alkoholos halálozási kategóriákon belül, és ezek összes halálozáson belüli aránya is megváltozott (az alkohollal kapcsolatos halálozásé számottevően csökkent, míg a daganatos halálozásé kisebb mértékben nőtt), az újabb vizsgálati periódusban a daganatos halálozásnak alkohollal kapcsolatos hányada mindkét nemben nőtt (a férfiak körében 60%-ra, a nők körében 9,1%-ra). Következtetés: Legfőbb epidemiológiai következtetésként megerősítést nyert, hogy a daganatos betegségek megelőzésének, különösen bizonyos lokalizációjú daganatok mint halálokok csökkentésének egyik kulcskérdése – megkülönböztetetten a férfiak körében – az alkoholabúzus visszaszorítása. Orv. Hetil., 2013, 154, 700–706.

  4. Initial Results from the Miniature Imager for Neutral Ionospheric Atoms and Magnetospheric Electrons (MINI-ME) on the FASTSAT Spacecraft

    NASA Technical Reports Server (NTRS)

    Collier, Michael R.; Rowland, Douglas; Keller, John W.; Chornay, Dennis; Khazanov, George; Herrero, Federico; Moore, Thomas E.; Kujawski, Joseph; Casas, Joseph C.; Wilson, Gordon

    2011-01-01

    The MINI-ME instrument is a collaborative effort between NASA's Goddard Space Flight Center (GSFC) and the U.S. Naval Academy, funded solely through GSFC Internal Research and Development (IRAD) awards. It detects neutral atoms from about 10 eV to about 700 eV (in 30 energy steps) in its current operating configuration with an approximately 10 degree by 360 degree field-of-view, divided into six sectors. The instrument was delivered on August 3, 2009 to Marshall Space Flight Center (MSFC) for integration with the FASTSAT-HSV01 small spacecraft bus developed by MSFC and a commercial partner, one of six Space Experiment Review Board (SERB) experiments on FASTSAT and one of three GSFC instruments (PISA and TTI being the other two). The FASTSAT spacecraft was launched on November 21, 2010 from Kodiak, Alaska on a Minotaur IV as a secondary payload and inserted into a 650 km, 72 degree inclination orbit, very nearly circular. MINI-ME has been collecting science data, as spacecraft resources would permit, in "optimal science mode" since January 20, 2011. In this presentation, we report initial science results including the potential first observations of neutral molecular ionospheric outflow. At the time of this abstract, we have identified 15 possible molecular outflow events. All these events occur between about 65 and 82 degrees geomagnetic latitude and most map to the auroral oval. The MINI-ME results provide an excellent framework for interpretation of the MILENA data, two instruments almost identical to MINI-ME that will launch on the VISIONS suborbital mission

  5. Efficient Flame Retardant Thin Films Synthesized by Atmospheric Pressure PECVD through the High Co-deposition Rate of Hexamethyldisiloxane and Triethylphosphate on Polycarbonate and Polyamide-6 Substrates.

    PubMed

    Hilt, Florian; Gherardi, Nicolas; Duday, David; Berné, Aurélien; Choquet, Patrick

    2016-05-18

    An innovative approach to produce high-performance and halogen-free flame-retardant thin films at atmospheric pressure is reported. PDMS-based coatings with embedded dopant-rich polyphosphates are elaborated thanks to a straightforward approach, using an atmospheric pressure dielectric barrier discharge (AP-DBD). Deposition conditions have been tailored to elaborate various thin films that can match the fire performance requirements. Morphology, chemical composition, and structure are investigated, and results show that the coatings performances are increased by taking advantage of the synergistic effect of P and Si flame retardant compounds. More specifically, this study relates the possibility to obtain flame retardant properties on PolyCarbonate and PolyAmide-6 thanks to their covering by a 5 μm thick coating, i.e. very thin films for this field of application, yet quite substantial for plasma processes. Hence, this approach enables deposition of flame retardant coatings onto different polymer substrates, providing a versatile fireproofing solution for different natures of polymer substrates. The presence of an expanded charred layer at the surface acts as a protective barrier limiting heat and mass transfer. This latter retains and consumes a part of the PC or PA-6 degradation byproducts and then minimizes the released flammable gases. It may also insulate the substrate from the flame and limit mass transfers of remaining volatile gases. Moreover, reactions in the condensed phase have also been highlighted despite the relatively thin thickness of the deposited layers. As a result of these phenomena, excellent performances are obtained, illustrated by a decrease of the peak of the heat release rate (pHRR) and an increase of the time to ignition (TTI).

  6. Tumor Touch Imprints as Source for Whole Genome Analysis of Neuroblastoma Tumors

    PubMed Central

    Brunner, Clemens; Brunner-Herglotz, Bettina; Ziegler, Andrea; Frech, Christian; Amann, Gabriele; Ladenstein, Ruth; Ambros, Inge M.; Ambros, Peter F.

    2016-01-01

    Introduction Tumor touch imprints (TTIs) are routinely used for the molecular diagnosis of neuroblastomas by interphase fluorescence in-situ hybridization (I-FISH). However, in order to facilitate a comprehensive, up-to-date molecular diagnosis of neuroblastomas and to identify new markers to refine risk and therapy stratification methods, whole genome approaches are needed. We examined the applicability of an ultra-high density SNP array platform that identifies copy number changes of varying sizes down to a few exons for the detection of genomic changes in tumor DNA extracted from TTIs. Material and Methods DNAs were extracted from TTIs of 46 neuroblastoma and 4 other pediatric tumors. The DNAs were analyzed on the Cytoscan HD SNP array platform to evaluate numerical and structural genomic aberrations. The quality of the data obtained from TTIs was compared to that from randomly chosen fresh or fresh frozen solid tumors (n = 212) and I-FISH validation was performed. Results SNP array profiles were obtained from 48 (out of 50) TTI DNAs of which 47 showed genomic aberrations. The high marker density allowed for single gene analysis, e.g. loss of nine exons in the ATRX gene and the visualization of chromothripsis. Data quality was comparable to fresh or fresh frozen tumor SNP profiles. SNP array results were confirmed by I-FISH. Conclusion TTIs are an excellent source for SNP array processing with the advantage of simple handling, distribution and storage of tumor tissue on glass slides. The minimal amount of tumor tissue needed to analyze whole genomes makes TTIs an economic surrogate source in the molecular diagnostic work up of tumor samples. PMID:27560999

  7. LANL receiver system development

    SciTech Connect

    Laubscher, B.; Cooke, B.; Cafferty, M.; Olivas, N.

    1997-08-01

    The CALIOPE receiver system development at LANL is the story of two technologies. The first of these technologies consists of off-the-shelf mercury-cadmium-telluride (MCT) detectors and amplifiers. The vendor for this system is Kolmar Technologies. This system was fielded in the Tan Trailer I (TTI) in 1995 and will be referred to in this paper as GEN I. The second system consists of a MCT detector procured from Santa Barbara Research Center (SBRC) and an amplifier designed and built by LANL. This system was fielded in the Tan Trailer II (TTII) system at the NTS tests in 1996 and will be referred to as GEN II. The LANL CALIOPE experimental plan for 1996 was to improve the lidar system by progressing to a higher rep rate laser to perform many shots in a much shorter period of time. In keeping with this plan, the receiver team set a goal of developing a detector system that was background limited for the projected 100 nanosecond (ns) laser pulse. A set of detailed simulations of the DIAL lidar experiment was performed. From these runs, parameters such as optimal detector size, field of view of the receiver system, nominal laser return power, etc. were extracted. With this information, detector physics and amplifier electronic models were developed to obtain the required specifications for each of these components. These derived specs indicated that a substantial improvement over commercially available, off-the-shelf, amplifier and detector technologies would be needed to obtain the goals. To determine if the original GEN I detector was usable, the authors performed tests on a 100 micron square detector at cryogenic temperatures. The results of this test and others convinced them that an advanced detector was required. Eventually, a suitable detector was identified and a number of these single element detectors were procured from SBRC. These single element detectors were witness for the detector arrays built for another DOE project.

  8. Evaluation of a Lagrangian box model using field measurements from EASE (Eastern Atlantic Summer Experiment) 1996

    NASA Astrophysics Data System (ADS)

    Evans, M. J.; Shallcross, D. E.; Law, K. S.; Wild, J. O. F.; Simmonds, P. G.; Spain, T. G.; Berrisford, P.; Methven, J.; Lewis, A. C.; McQuaid, J. B.; Pilling, M. J.; Bandy, B. J.; Penkett, S. A.; Pyle, J. A.

    The Cambridge Tropospheric Trajectory model of Chemistry and Transport (CiTTyCAT), a Lagrangian chemistry model, has been evaluated using atmospheric chemical measurements collected during the East Atlantic Summer Experiment 1996 (EASE '96). This field campaign was part of the UK Natural Environment Research Council's (NERC) Atmospheric Chemistry Studies in the Oceanic Environment (ACSOE) programme, conducted at Mace Head, Republic of Ireland, during July and August 1996. The model includes a description of gas-phase tropospheric chemistry, and simple parameterisations for surface deposition, mixing from the free troposphere and emissions. The model generally compares well with the measurements and is used to study the production and loss of O 3 under a variety of conditions. The mean difference between the hourly O 3 concentrations calculated by the model and those measured is 0.6 ppbv with a standard deviation of 8.7 ppbv. Three specific air-flow regimes were identified during the campaign - westerly, anticyclonic (easterly) and south westerly. The westerly flow is typical of background conditions for Mace Head. However, on some occasions there was evidence of long-range transport of pollutants from North America. In periods of anticyclonic flow, air parcels had collected emissions of NO x and VOCs immediately before arriving at Mace Head, leading to O 3 production. The level of calculated O 3 depends critically on the precise details of the trajectory, and hence on the emissions into the air parcel. In several periods of south westerly flow, low concentrations of O 3 were measured which were consistent with deposition and photochemical destruction inside the tropical marine boundary layer.

  9. Effects of sound intensity on temporal properties of inhibition in the pallid bat auditory cortex.

    PubMed

    Razak, Khaleel A

    2013-01-01

    Auditory neurons in bats that use frequency modulated (FM) sweeps for echolocation are selective for the behaviorally-relevant rates and direction of frequency change. Such selectivity arises through spectrotemporal interactions between excitatory and inhibitory components of the receptive field. In the pallid bat auditory system, the relationship between FM sweep direction/rate selectivity and spectral and temporal properties of sideband inhibition have been characterized. Of note is the temporal asymmetry in sideband inhibition, with low-frequency inhibition (LFI) exhibiting faster arrival times compared to high-frequency inhibition (HFI). Using the two-tone inhibition over time (TTI) stimulus paradigm, this study investigated the interactions between two sound parameters in shaping sideband inhibition: intensity and time. Specifically, the impact of changing relative intensities of the excitatory and inhibitory tones on arrival time of inhibition was studied. Using this stimulation paradigm, single unit data from the auditory cortex of pentobarbital-anesthetized cortex show that the threshold for LFI is on average ~8 dB lower than HFI. For equal intensity tones near threshold, LFI is stronger than HFI. When the inhibitory tone intensity is increased further from threshold, the strength asymmetry decreased. The temporal asymmetry in LFI vs. HFI arrival time is strongest when the excitatory and inhibitory tones are of equal intensities or if excitatory tone is louder. As inhibitory tone intensity is increased, temporal asymmetry decreased suggesting that the relative magnitude of excitatory and inhibitory inputs shape arrival time of inhibition and FM sweep rate and direction selectivity. Given that most FM bats use downward sweeps as echolocation calls, a similar asymmetry in threshold and strength of LFI vs. HFI may be a general adaptation to enhance direction selectivity while maintaining sweep-rate selective responses to downward sweeps.

  10. Real-time performance modeling of (3G) UMTS system

    NASA Astrophysics Data System (ADS)

    Badrinath, R.; Mitra, Abhijit; Sinha, Nishant; Mukherjee, Niloy

    2001-11-01

    Universal Mobile Telecommunications System (UMTS) wireless technologies is a proposed standardization as a part of 3GPP solutions to satisfy IMT-2000 requirements. It is based on wideband CDMA technology. It will provide full coverage and mobility for 144 Kb/s, preferably 384 Kb/s and limited coverage and mobility for 2 Mb/s. It proposes high spectrum efficiency compared to existing systems, handling of different QOS profiles and high flexibility to introduce new service. In this paper, we present our work on modeling of the access stratum (AS) on the User Equipment/Mobile Termination (UE/MT) side of the radio (Uu) interface in accordance with 3GPP UMTS standards. The AS has the following sub-layers: Medium Access Control/Radio Link Control (MAC/RLC), Broadcast Multicast Control (BMC), Packet Data Convergence Protocol (PDCP) and Radio Resource Control (RRC). We have assumed the number of transport channels interfacing the AS MAC sub layer and the physical layer to be eight. The data rates have been assumed to be 384 Kb/s per transport channel both in uplink and downlink. Processing in each sub-layer with corresponding delays and interaction between adjacent sublayers having timing restrictions or rate restrictions have been analyzed. Interaction of the upper sub-layers with the non-access stratum (NAS) and interaction between peer AS sub-layers in the UE and the UTRAN have also been incorporated. A real time priority based scheduler process has been specified to honor the time restrictions e.g. the Transmission Time Intervals (TTI) of the channels. The system has been simulated on Virtual Silicon, a C based SDL tool and evaluated on CR16C architecture family using CR16C debugger, both developed by National Semi Conductor Corp., U.S.A.

  11. Effects of sound intensity on temporal properties of inhibition in the pallid bat auditory cortex

    PubMed Central

    Razak, Khaleel A.

    2013-01-01

    Auditory neurons in bats that use frequency modulated (FM) sweeps for echolocation are selective for the behaviorally-relevant rates and direction of frequency change. Such selectivity arises through spectrotemporal interactions between excitatory and inhibitory components of the receptive field. In the pallid bat auditory system, the relationship between FM sweep direction/rate selectivity and spectral and temporal properties of sideband inhibition have been characterized. Of note is the temporal asymmetry in sideband inhibition, with low-frequency inhibition (LFI) exhibiting faster arrival times compared to high-frequency inhibition (HFI). Using the two-tone inhibition over time (TTI) stimulus paradigm, this study investigated the interactions between two sound parameters in shaping sideband inhibition: intensity and time. Specifically, the impact of changing relative intensities of the excitatory and inhibitory tones on arrival time of inhibition was studied. Using this stimulation paradigm, single unit data from the auditory cortex of pentobarbital-anesthetized cortex show that the threshold for LFI is on average ~8 dB lower than HFI. For equal intensity tones near threshold, LFI is stronger than HFI. When the inhibitory tone intensity is increased further from threshold, the strength asymmetry decreased. The temporal asymmetry in LFI vs. HFI arrival time is strongest when the excitatory and inhibitory tones are of equal intensities or if excitatory tone is louder. As inhibitory tone intensity is increased, temporal asymmetry decreased suggesting that the relative magnitude of excitatory and inhibitory inputs shape arrival time of inhibition and FM sweep rate and direction selectivity. Given that most FM bats use downward sweeps as echolocation calls, a similar asymmetry in threshold and strength of LFI vs. HFI may be a general adaptation to enhance direction selectivity while maintaining sweep-rate selective responses to downward sweeps. PMID:23761762

  12. Behavior and Release of Nitrogen at Mines and Quarries in Nordic Conditions

    NASA Astrophysics Data System (ADS)

    Karlsson, Teemu; Neitola, Raisa; Jermakka, Johannes; Merta, Elina; Mroueh, Ulla-Maija

    2015-04-01

    project with GTK, VTT and TTY together with several industrial and international partners and financed by Tekes Green Mining Programme.

  13. Prospective evaluation of a matrix-assisted laser desorption ionization-time of flight mass spectrometry system in a hospital clinical microbiology laboratory for identification of bacteria and yeasts: a bench-by-bench study for assessing the impact on time to identification and cost-effectiveness.

    PubMed

    Tan, K E; Ellis, B C; Lee, R; Stamper, P D; Zhang, S X; Carroll, K C

    2012-10-01

    Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has been found to be an accurate, rapid, and inexpensive method for the identification of bacteria and yeasts. Previous evaluations have compared the accuracy, time to identification, and costs of the MALDI-TOF MS method against standard identification systems or commercial panels. In this prospective study, we compared a protocol incorporating MALDI-TOF MS (MALDI protocol) with the current standard identification protocols (standard protocol) to determine the performance in actual practice using a specimen-based, bench-by-bench approach. The potential impact on time to identification (TTI) and costs had MALDI-TOF MS been the first-line identification method was quantitated. The MALDI protocol includes supplementary tests, notably for Streptococcus pneumoniae and Shigella, and indications for repeat MALDI-TOF MS attempts, often not measured in previous studies. A total of 952 isolates (824 bacterial isolates and 128 yeast isolates) recovered from 2,214 specimens were assessed using the MALDI protocol. Compared with standard protocols, the MALDI protocol provided identifications 1.45 days earlier on average (P < 0.001). In our laboratory, we anticipate that the incorporation of the MALDI protocol can reduce reagent and labor costs of identification by $102,424 or 56.9% within 12 months. The model included the fixed annual costs of the MALDI-TOF MS, such as the cost of protein standards and instrument maintenance, and the annual prevalence of organisms encountered in our laboratory. This comprehensive cost analysis model can be generalized to other moderate- to high-volume laboratories.

  14. Petroleum geochemistry of oils and rocks in Arctic National Wildlife Refuge, Alaska

    SciTech Connect

    Magoon, L.B.; Anders, D.E.

    1987-05-01

    Thirteen oil seeps or oil-stained outcrops in or adjacent to the coastal plain of the Arctic National Wildlife Refuge (ANWR) in northeastern Alaska indicate that commercial quantities of hydrocarbons may be present in the subsurface. The area is flanked by two important petroleum provinces: the Prudhoe Bay area on the west and the Mackenzie delta on the east. Organic carbon content (wt. %), organic matter type, and pyrolysis hydrocarbon yield show that rock units such as the Kingak Shale (average 1.3 wt. %), pebble shale unit (2.1 wt. %), and Canning Formation (1.9 wt. %) contain predominantly type III organic matter. The exception is the Hue Shale (5.9 wt. %), which contains type II organic matter. Pre-Cretaceous rocks that crop out in the Brooks Range could not be adequately evaluated because of high thermal maturity. Thermal maturity thresholds for oil, condensate, and gas calculated from vitrinite reflectance gradients in the Point Thomson area are 4000, 7300, and 9330 m, respectively (12,000, 22,500, and 28,000 ft). Time-temperature index (TTI) calculations for the Beli-1 and Point Thomson-1 wells immediately west of ANWR indicate that maturity first occurred in the south and progressed north. The Cretaceous Hue Shale matured in the Beli-1 well during the Eocene and in the Point Thomson-1 well in the late Miocene to early Pliocene. In the Point Thomson area, the condensate and gas recovered from the Thomson sandstone and basement complex based on API gravity and gas/oil ratio (GOR) probably originated from the pebble shale unit, and on the same basis, the oil recovered from the Canning Formation probably originated from the Hue Shale. The gas recovered from the three wells in the Kavik area is probably thermal gas from overmature source rocks in the immediate area.

  15. Relative risk of reducing the lifetime blood donation deferral for men who have had sex with men versus currently tolerated transfusion risks.

    PubMed

    Vamvakas, Eleftherios C

    2011-01-01

    The risks of known and emerging transfusion-transmitted infections (TTIs) from reducing the current lifetime blood donation deferral for men who have had sex with men (MSM) to 1 or 5 years were compared to the risk from continuing to transfuse in the United States 12.5% of platelet doses as pooled whole-blood-derived (rather than single-donor) platelets. Assumptions made in mathematical models and blood donor/transfusion studies of the risks of TTIs since 2000 were evaluated. The number of HIV, hepatitis B virus, or hepatitis C virus TTIs from reducing the MSM deferral to 1 year is, respectively, 0.88, 2.94, or 66.9, many more than 10 times smaller than the risk from pooled platelets. If erroneous release of HIV-positive units (a risk independent of a donor's source of infection) is not considered, the MSM risk is 1 HIV-infectious donation per 17 to 56 million MSM donations. Any purportedly increased risk of human herpesvirus-8 transmission from MSM donors is far smaller than the risk of transfusion-associated sepsis from pooled platelets. Single-donor platelets from MSM after 5 years' abstinence are as safe or 5 times safer than our current pooled platelets--if the next TTI to emerge were transmitted, respectively, sexually or by another route. Thus, acceptance of MSM as blood donors after 1 or 5 years' abstinence may result in a postulated increase in risk that is so much smaller than the currently tolerated transfusion risk and so small in absolute terms that the ethical question of fairness to the MSM group justifies the change in policy.

  16. Men having sex with men donor deferral risk assessment: an analysis using risk management principles.

    PubMed

    Leiss, William; Tyshenko, Michael; Krewski, Daniel

    2008-01-01

    This article discusses issues associated with the lifetime deferral from donating blood of men having sex with men (MSM), in the context of well-established risk management principles, including ethical considerations associated with the risk-based approach to social policy matters. Specifically, it deals with the questions about the rationale for the existing policy in Canada of lifetime deferral for MSM, a rationale applied in practice by blood collection agencies and supported by the regulatory authority of Health Canada. We identify several alternative time frames for MSM deferral: sexual abstinence over either a 10-, 5-, or 1-year period or no deferral. Two options are selected for more complete discussion, namely, abstinence for a period of either 1 or 5 years before donation. The available evidence about estimated residual risk (RR)-that is, the risk remaining after various safeguards for blood are applied-strongly suggests that choosing a 1-year deferral period for MSM would almost certainly give rise to an incremental risk of transfusion-transmitted infection (TTI), over existing levels of risk, for blood recipients. The report argues that, under these circumstances, such a policy change would represent an unethical type of risk transfer, from one social group to another, and therefore would be unacceptable. The evidence is less clear when it comes to a change to either a 10- or 5-year deferral period. This is the case in part because the current level of RR is so low that there are, inevitably, substantial ranges of uncertainties associated with the risk estimation. There is no firm evidence that such a change in the deferral period for MSM would result in an incremental level of risk, although the possibility of a very small increase in risk cannot be entirely ruled out. Under these circumstances, other social policy issues, relevant to the idea of changing the deferral period for MSM, become worthy of additional consideration.

  17. Development of blood transfusion product pathogen reduction treatments: a review of methods, current applications and demands.

    PubMed

    Salunkhe, Vishal; van der Meer, Pieter F; de Korte, Dirk; Seghatchian, Jerard; Gutiérrez, Laura

    2015-02-01

    Transfusion-transmitted infections (TTI) have been greatly reduced in numbers due to the strict donor selection and screening procedures, i.e. the availability of technologies to test donors for endemic infections, and routine vigilance of regulatory authorities in every step of the blood supply chain (collection, processing and storage). However, safety improvement is still a matter of concern because infection zero-risk in transfusion medicine is non-existent. Alternatives are required to assure the safety of the transfusion product and to provide a substitution to systematic blood screening tests, especially in less-developed countries or at the war-field. Furthermore, the increasing mobility of the population due to traveling poses a new challenge in the endemic screening tests routinely used, because non-endemic pathogens might emerge in a specific population. Pathogen reduction treatments sum a plethora of active approaches to eliminate or reduce potential threatening pathogen load from blood transfusion products. Despite the success of pathogen reduction treatments applied to plasma products, there is still a long way to develop and deploy pathogen reduction treatments to cellular transfusion products (such as platelets, RBCs or even to whole blood) and there is divergence on its acceptance worldwide. While the use of pathogen reduction treatments in platelets is performed routinely in a fair number of European blood banks, most of these treatments are not (or just) licensed in the USA or elsewhere in the world. The development of pathogen reduction treatments for RBC and whole blood is still in its infancy and under clinical trials. In this review, we discuss the available and emerging pathogen reduction treatments and their advantages and disadvantages. Furthermore, we highlight the importance of characterizing standard transfusion products with current and emerging approaches (OMICS) and clinical outcome, and integrating this information on a database

  18. Initial Results from the Miniature Imager for Neutral Ionospheric atoms and Magnetospheric Electrons (MINI-ME) on the FASTSAT Spacecraft

    NASA Astrophysics Data System (ADS)

    Collier, M. R.; Rowland, D. E.; Keller, J. W.; Chornay, D. J.; Khazanov, G. V.; Herrero, F.; Moore, T. E.; Kujawski, J. T.; Casas, J. C.; Wilson, G. R.

    2011-12-01

    The MINI-ME instrument is a collaborative effort between NASA's Goddard Space Flight Center (GSFC) and the U.S. Naval Academy, funded solely through GSFC Internal Research and Development (IRAD) awards. It detects neutral atoms from about 10 eV to about 700 eV (in 30 energy steps) in its current operating configuration with an approximately 10 degree by 360 degree field-of-view, divided into six sectors. The instrument was delivered on August 3, 2009 to Marshall Space Flight Center (MSFC) for integration with the FASTSAT-HSV01 small spacecraft bus developed by MSFC and a commercial partner, one of six Space Experiments Review Board (SERB) experiments on FASTSAT and one of three GSFC instruments (PISA and TTI being the other two). The FASTSAT spacecraft was launched on November 21, 2010 from Kodiak, Alaska on a Minotaur IV as a secondary payload and inserted into a 650 km, 72 degree inclination orbit, very nearly circular. MINI-ME has been collecting science data, as spacecraft resources would permit, in "optimal science mode" since January 20, 2011. In this presentation, we report initial science results including the potential first observations of neutral molecular ionospheric outflow. At the time of this abstract, we have identified 15 possible molecular outflow events. All these events occur between about 65 and 82 degrees geomagnetic latitude and most map to the auroral oval. The MINI-ME results provide an excellent framework for interpretation of the MILENA data, two instruments almost identical to MINI-ME that will launch on the VISIONS suborbital mission (PI: Douglas Rowland).

  19. Namibia’s transition from whole blood–derived pooled platelets to single-donor apheresis platelet collections

    PubMed Central

    Pitman, John P.; Basavaraju, Sridhar V.; Shiraishi, Ray W.; Wilkinson, Robert; von Finckenstein, Bjorn; Lowrance, David W.; Marfin, Anthony A.; Postma, Maarten; Mataranyika, Mary; Sibinga, Cees Th. Smit

    2015-01-01

    BACKGROUND Few African countries separate blood donations into components; however, demand for platelets (PLTs) is increasing as regional capacity to treat causes of thrombocytopenia, including chemotherapy, increases. Namibia introduced single-donor apheresis PLT collections in 2007 to increase PLT availability while reducing exposure to multiple donors via pooling. This study describes the impact this transition had on PLT availability and safety in Namibia. STUDY DESIGN AND METHODS Annual national blood collections and PLT units issued data were extracted from a database maintained by the Blood Transfusion Service of Namibia (NAMBTS). Production costs and unit prices were analyzed. RESULTS In 2006, NAMBTS issued 771 single and pooled PLT doses from 3054 whole blood (WB) donations (drawn from 18,422 WB donations). In 2007, NAMBTS issued 486 single and pooled PLT doses from 1477 WB donations (drawn from 18,309 WB donations) and 131 single-donor PLT doses. By 2011, NAMBTS issued 837 single-donor PLT doses per year, 99.1% of all PLT units. Of 5761 WB donations from which PLTs were made in 2006 to 2011, a total of 20 (0.35%) were from donors with confirmed test results for human immunodeficiency virus or other transfusion-transmissible infections (TTIs). Of 2315 single-donor apheresis donations between 2007 and 2011, none of the 663 donors had a confirmed positive result for any pathogen. As apheresis replaced WB-derived PLTs, apheresis production costs dropped by a mean of 8.2% per year, while pooled PLT costs increased by an annual mean of 21.5%. Unit prices paid for apheresis- and WB-derived PLTs increased by 9 and 7.4% per year on average, respectively. CONCLUSION Namibia’s PLT transition shows that collections from repeat apheresis donors can reduce TTI risk and production costs. PMID:25727921

  20. Estimation of carbon dioxide emissions per urban center link unit using data collected by the Advanced Traffic Information System in Daejeon, Korea

    NASA Astrophysics Data System (ADS)

    Ryu, B. Y.; Jung, H. J.; Bae, S. H.; Choi, C. U.

    2013-12-01

    CO2 emissions on roads in urban centers substantially affect global warming. It is important to quantify CO2 emissions in terms of the link unit in order to reduce these emissions on the roads. Therefore, in this study, we utilized real-time traffic data and attempted to develop a methodology for estimating CO2 emissions per link unit. Because of the recent development of the vehicle-to-infrastructure (V2I) communication technology, data from probe vehicles (PVs) can be collected and speed per link unit can be calculated. Among the existing emission calculation methodologies, mesoscale modeling, which is a representative modeling measurement technique, requires speed and traffic data per link unit. As it is not feasible to install fixed detectors at every link for traffic data collection, in this study, we developed a model for traffic volume estimation by utilizing the number of PVs that can be additionally collected when the PV data are collected. Multiple linear regression and an artificial neural network (ANN) were used for estimating the traffic volume. The independent variables and input data for each model are the number of PVs, travel time index (TTI), the number of lanes, and time slots. The result from the traffic volume estimate model shows that the mean absolute percentage error (MAPE) of the ANN is 18.67%, thus proving that it is more effective. The ANN-based traffic volume estimation served as the basis for the calculation of emissions per link unit. The daily average emissions for Daejeon, where this study was based, were 2210.19 ton/day. By vehicle type, passenger cars accounted for 71.28% of the total emissions. By road, Gyeryongro emitted 125.48 ton/day, accounting for 5.68% of the total emission, the highest percentage of all roads. In terms of emissions per kilometer, Hanbatdaero had the highest emission volume, with 7.26 ton/day/km on average. This study proves that real-time traffic data allow an emissions estimate in terms of the link unit

  1. Thermal instability and the feedback regulation of hot haloes in clusters, groups and galaxies

    NASA Astrophysics Data System (ADS)

    Sharma, Prateek; McCourt, Michael; Quataert, Eliot; Parrish, Ian J.

    2012-03-01

    We present global multidimensional numerical simulations of the plasma that pervades the dark matter haloes of clusters, groups and massive galaxies (the 'intracluster medium'; ICM). Observations of clusters and groups imply that such haloes are roughly in global thermal equilibrium, with heating balancing cooling when averaged over sufficiently long time- and length-scales; the ICM is, however, very likely to be locally thermally unstable. Using simple observationally motivated heating prescriptions, we show that local thermal instability (TI) can produce a multiphase medium - with ˜ 104 K cold filaments condensing out of the hot ICM - only when the ratio of the TI time-scale in the hot plasma (tTI) to the free-fall time-scale (tff) satisfies tTI/tff≲ 10. This criterion quantitatively explains why cold gas and star formation are preferentially observed in low-entropy clusters and groups. In addition, the interplay among heating, cooling and TI reduces the net cooling rate and the mass accretion rate at small radii by factors of ˜ 100 relative to cooling-flow models. This dramatic reduction is in line with observations. The feedback efficiency required to prevent a cooling flow is ˜ 10-3 for clusters and decreases for lower mass haloes; supernova heating may be energetically sufficient to balance cooling in galactic haloes. We further argue that the ICM self-adjusts so that tTI/tff≳ 10 at all radii. When this criterion is not satisfied, cold filaments condense out of the hot phase and reduce the density of the ICM. These cold filaments can power the black hole and/or stellar feedback required for global thermal balance, which drives tTI/tff≳ 10. In comparison to clusters, groups have central cores with lower densities and larger radii. This can account for the deviations from self-similarity in the X-ray luminosity-temperature (?) relation. The high-velocity clouds observed in the Galactic halo can be due to local TI producing multiphase gas close to the

  2. Sediment-pore water interactions controlling cementation in the NanTroSEIZE drilling transects

    NASA Astrophysics Data System (ADS)

    Hong, W.; Spinelli, G. A.; Torres, M. E.

    2012-12-01

    dissolved silicate released from ash alteration precipitates as cement, inhibiting consolidation. At or below the boundary, the increase in pH (>8.0), leads to oversaturation (and precipitation) of clinoptilolite. Strong demand of dissolved silicate due to clinoptilolite formation soon depletes the dissolved potassium and silicate; ash and silicate cement are forced to dissolve. The exact set of reactions resulting on the observed pH increase is still unclear, but it likely involves the carbon system. It is noteworthy that the diagenetic boundary at all sites in the incoming plate occurs at the same thermal maturity of the sediments (TTI=0.025), similar to observations on onshore sequences in Japan (Sasaki, 1986).

  3. Hybrid FES-robot cooperative control of ambulatory gait rehabilitation exoskeleton.

    PubMed

    del-Ama, Antonio J; Gil-Agudo, Angel; Pons, José L; Moreno, Juan C

    2014-03-04

    stimulation; HKAFO: hip-knee-ankle-foot orthosis; ILC: iterative error-based learning control; MFE: muscle fatigue estimator; NILC: Normalized stimulation output from ILC controller; PID: Proportional-Integral-derivative Control; PW: Stimulation pulse width; QUEST: Quebec User Evaluation of Satisfaction with assistive Technology; SCI: Spinal cord injury; TTI: torque-time integral; VAS: Visual Analog Scale.

  4. Hybrid FES-robot cooperative control of ambulatory gait rehabilitation exoskeleton

    PubMed Central

    2014-01-01

    stimulation; HKAFO: hip-knee-ankle-foot orthosis; ILC: iterative error-based learning control; MFE: muscle fatigue estimator; NILC: Normalized stimulation output from ILC controller; PID: Proportional-Integral-derivative Control; PW: Stimulation pulse width; QUEST: Quebec User Evaluation of Satisfaction with assistive Technology; SCI: Spinal cord injury; TTI: torque-time integral; VAS: Visual Analog Scale. PMID:24594302

  5. Modelling component evaporation and composition change of traffic-induced ultrafine particles during travel from street canyon to urban background.

    PubMed

    Nikolova, Irina; MacKenzie, A Rob; Cai, Xiaoming; Alam, Mohammed S; Harrison, Roy M

    2016-07-18

    We developed a model (CiTTy-Street-UFP) of traffic-related particle behaviour in a street canyon and in the nearby downwind urban background that accounts for aerosol dynamics and the variable vapour pressure of component organics. The model simulates the evolution and fate of traffic generated multicomponent ultrafine particles (UFP) composed of a non-volatile core and 17 Semi-Volatile Organic Compounds (SVOC, modelled as n-alkane proxies). A two-stage modelling approach is adopted: (1) a steady state simulation inside the street canyon is achieved, in which there exists a balance between traffic emissions, condensation/evaporation, deposition, coagulation and exchange with the air above roof-level; and (2) a continuing simulation of the above-roof air parcel advected to the nearby urban park during which evaporation is dominant. We evaluate the component evaporation and associated composition changes of multicomponent organic particles in realistic atmospheric conditions and compare our results with observations from London (UK) in a street canyon and an urban park. With plausible input conditions and parameter settings, the model can reproduce, with reasonable fidelity, size distributions in central London in 2007. The modelled nucleation-mode peak diameter, which is 23 nm in the steady-state street canyon, decreases to 9 nm in a travel time of just 120 s. All modelled SVOC in the sub-10 nm particle size range have evaporated leaving behind only non-volatile material, whereas modelled particle composition in the Aitken mode contains SVOC between C26H54 and C32H66. No data on particle composition are available in the study used for validation, or elsewhere. Measurements addressing in detail the size resolved composition of the traffic emitted UFP in the atmosphere are a high priority for future research. Such data would improve the representation of these particles in dispersion models and provide the data essential for model validation. Enhanced knowledge of the

  6. Effects of weathering on performance of intumescent coatings for structure fire protection in the wildland-urban interface

    NASA Astrophysics Data System (ADS)

    Bahrani, Babak

    as SDT). For each coating type and weathering period, three different radiative heat flux levels were used in the combustibility tests. Data obtained from the tests, including flammability and thermal properties, were gathered, analyzed, and compared to non-weathered specimens. The results revealed visible effects of weathering on pre (and up to)-ignition flammability and intumescent properties, especially decreases in Time-to-Ignition (TTI), Time-to-Intumescence (tintu.), and (maximum) Intumescence Height (Hintu.) values in weathered specimens. These results showed that the ignition resistance of the coating layers decreased after weathering exposure. On the other hand, the obtained results from weathered specimens for the post-ignition flammability properties, especially Peak Heat Release Rate (PHRR) and Effective Heat of Combustion (EHC) did not show a significant difference in comparison to the non-weathered samples. These results demonstrated that the weathered coating layer would not likely to act as an additional combustible fuel to increase fire spread.

  7. Crustal Structure, Seismic Anisotropy and Deformations of the Ediacaran/Cambrian of the Małopolska Block in SE Poland Based on Data from Two Seismic Wide-Angle Experiments

    NASA Astrophysics Data System (ADS)

    Środa, Piotr

    2017-03-01

    tight (sub-vertical) folding and fracturing of intrinsically anisotropic metasediments forming the MB basement. Obtained anisotropy models are compared with data about stratal dips of the MB sequences and implications of assuming more realistic TTI model are discussed. Wide-angle recordings from off-line measurements along a reflection profile provided new information about seismic velocity and anisotropy, not available from standard near-vertical profiling, and contributed to more complete image of the upper crustal structure of Małopolska Block.

  8. [Long-term treatment with intravitreal ranibizumab for exudative age-related macular degeneration].

    PubMed

    Lukács, Regina; Resch, Miklós; Papp, András; Szabó, Antal; Borbándy, Ágnes; Menkens, Hanna; Kiss, Huba; Németh, János

    2013-11-10

    Bevezetés: Az exsudativ időskori maculadegeneráció kezelésére alkalmazott intravitrealis ranibizumabinjekcióval szerzett eddigi tapasztalatok kedvezőek. Célkitűzés: A szerzők célul tűzték ki az intravitrealis ranibizumabterápia kétéves/hosszú távú funkcionális és anatómiai eredményeinek felmérését. Módszer: Egycentrumú prospektív vizsgálatban 46 beteg (átlagéletkor: 75±9,1 év) adatait dolgozták fel. A kezelési protokoll szerint a betegek az első három hónapban havonta kaptak 0,5 mg ranibizumabinjekciót, majd szükség szerint (pro re nata). A legjobb korrigált visus, illetve a centrális retinavastagság változását követték. Eredmények: A legjobb korrigált látóélesség változása a követési idő végére sem a kezelés előtti értékhez képest (p = 0,760), sem az első év végi eredményhez képest nem volt statisztikailag szignifikáns (p = 0,154). A centrális retinavastagság a kiindulási értékhez képest szignifikánsan csökkent (p = 0,000001), az első év végi értékhez képest nem volt szignifikáns a változás (p = 0,875). Következtetések: Nedves típusú maculadegenerációban szenvedő betegeknél pro re nata protokoll szerinti intravitrealis ranibizumabkezeléssel hosszú távon a látóélesség stabil marad, az exsudatio hatékonyan csökkenthető Orv. Hetil., 2013, 154(45), 1790–1797.

  9. Evaluating the effects of herbicide drift on non-target terrestrial plants: A case study with mesotrione.

    PubMed

    Brain, Richard A; Perine, Jeff; Cooke, Catriona; Butler Ellis, Clare; Harrington, Paul; Lane, Andrew; Sullivan, Christine; Ledson, Mark

    2017-03-06

    Nature of exposure is a fundamental driver in non-target terrestrial plant (NTTP) risk assessment for pesticides, consequently a novel study was designed to generate field-based drift exposure and evaluate corresponding biological effects of the herbicide mesotrione. The approach used a combination of U.S. guideline drift reduction technology (DRT) and vegetative vigor approaches. In each of three independent replicate spray application trials, ten pots each of lettuce and tomato were placed at distances of 10, 20, 30, 40 and 50 ft (∼3, 6, 9, 12, and 15 m) from the downwind edge of the spray boom. Each application was conducted using a commercial 60 ft (18 m) boom sprayer fitted with TeeJet® Technologies TTI110025 nozzles, with a nominal application rate of 0.2 lb a.i./A (224 g a.i./ha). The environmental conditions required by the protocol (air temperature 10 - 30°C and wind perpendicular to the swath (± 30°) blowing toward the plants at a mean wind speed of ≥10 mph [≥4.5 m/s] measured at 2.0 m above the ground) were met for each application. Following exposure, plants were transferred to a greenhouse for the 21-day vegetative vigor phase of the study. Symptoms of phytotoxicity and plant height were assessed at 7, 14 and 21 days after treatment (DAT). On completion of the 21 DAT assessment, all plants were harvested and dried in an oven to determine shoot dry weight. The biological data indicated that there were no statistically significant effects observed at a distance of 30 ft (∼9 m) from mesotrione drift at wind speeds of ≥10 mph (10.9 to 12.4 mph); this endpoint (30 ft) is defined as the No Observed Effects Distance (NOED). This article is protected by copyright. All rights reserved.

  10. [Antimicrobal resistance of Neisseria gonorrhoeae strains in Hungary].

    PubMed

    Nemes-Nikodém, Éva; Brunner, Alexandra; Tóth, Béla; Tóth, Veronika; Bánvölgyi, András; Ostorházi, Eszter

    2015-02-08

    Bevezetés: A Neisseria gonorrhoeae-infekciók kezelésére kiadott európai ajánlás elsősorban a nyugat-európai adatok alapján készült, és nem egyértelműen használható a magyarországi helyzet ismeretében. Célkitűzés: A szerzők 2011. január és 2014. június közötti időszakban a Semmelweis Egyetem, Bőr-, Nemikórtani és Bőronkológiai Klinika Országos Szexuális Úton Terjedő Betegségek Centrumában izolált Neisseria gonorrhoeae törzsek rezisztenciaadatait összevetették az izolált törzsek molekuláris tipizálási eredményeivel, azzal a céllal, hogy pontos adatokat kapjanak a hazánkban előforduló Neisseria gonorrhoeae törzsek antimikrobiális rezisztenciájáról. Módszer: Az antibiotikumrezisztencia-meghatározás minimális inhibitorkoncentráció-méréssel, a szekvenciameghatározás a Neisseria gonorrhoeae Multi Antigen Sequence Typing módszerrel történt. Eredmények: A jelenleg terápiának ajánlott széles spektrumú cefalosporinok elleni rezisztencia ritka, az utóbbi években az azithromycinrezisztencia előfordulása viszont rohamosan növekedett. Következtetések: Az új terápiás irányelvek készítésekor figyelembe kell venni, hogy a gyakran fertőzést okozó molekuláris típusba sorolható törzsek között kiemelkedően magas az azithromycinrezisztensek aránya. Orv. Hetil., 2015, 156(6), 226–229.

  11. [Lipid-lowering therapy and patient adherence in the MULTI GAP 2013 trial].

    PubMed

    Simonyi, Gábor

    2014-04-27

    Bevezetés: A dyslipidaemia ismert cardiovascularis kockázati tényező. A lipidterápiában a célértékek elérésének fontos tényezője a megfelelő betegadherencia. Célkitűzés: A MULTI GAP (MULTI Goal Attainment Problem) 2013-as vizsgálatban atheroscleroticus betegségben szenvedő betegek esetében a statinterápia adherenciájának és perzisztenciájának felmérése, amely részben a vizsgálatban részt vevő orvosok becslésén, illetve 319, a megelőző évben elvégzett MULTI GAP vizsgálatban részt vett beteg esetében az Országos Egészségbiztosítási Pénztár vénykiváltási adatbázisán alapult. Módszer: A MULTI GAP 2013 vizsgálatban standard, strukturált kérdőívek segítségével 1519 beteg adatai kerültek feldolgozásra. Az elemzésben kiértékelésre kerültek az egyes ellátási szinteken elért lipidértékek, a kezelőorvos által vélt betegadherencia, a 319 beteg Országos Egészségbiztosítási Pénztár vénykiváltási adataira támaszkodó valós adherencia, a kezelőorvosok elégedettsége a statinterápia eredményeivel, illetve az adherencia és a lipideredmények összevetése. Eredmények: Az elmúlt 7 év felméréseinek adatait is figyelembe véve előtérbe kerültek a hatékonyabb statinok; az atorvastatin és rozuvastatin alkalmazásának összesített aránya 49%-ról 83%-ra, azaz mintegy 70%-kal nőtt. A betegadherencia vonatkozásában kimutatták, hogy a 2,5 mmol/l alatti LDL-koleszterin-értékeket elért betegeknél az 1 év alatt kiváltott receptek száma mintegy nyolc gyógyszertári beváltást jelentett. Ehhez képest a 2,5 mmol/l feletti LDL-koleszterin-értékű csoportban a gyógyszerkiváltás lényegesen alacsonyabb volt (5,3 és 6,3 közötti). Éves szinten a 10–12 és a 7–9 gyógyszerkiváltás szignifikánsan alacsonyabb LDL-koleszterin-szintet jelentett a semennyit (0), illetve az 1–3 receptet éves szinten kiváltók csoportjaihoz képest. A kezelőorvosok által 100%-os

  12. [Cognitive functions in type 1 and type 2 diabetes. Meta-analysis].

    PubMed

    Kálcza-Jánosi, Kinga; Lukács, Andrea; Barkai, László; Szamosközi, István

    2013-05-05

    Bevezetés: A cukorbetegséget különféle kognitív károsodásokkal társítják. Célkitűzés: A szerzők 1-es és 2-es típusú diabetesben a kognitív működés közötti különbségek pontosítását tűzték ki célul. Módszer: Metaanalízis a Medline, PubMed és ScienceDirect felhasználásával (három tanulmány az 1-es és hat tanulmány a 2-es típusú cukorbetegséggel kapcsolatban). Eredmények: Az 1-es típusú cukorbeteg felnőttek teljesítménye gyengébb volt a kontrollokhoz képest az összes mért területen. A hatásméret a pszichomotoros aktivitásnál volt a legmagasabb (D = –0,69). Kicsi volt a hatásméret a késleltetett verbális memória (D = –0,48), figyelem (D = –0,47), nyelv (D = –0,44), vizuális feldolgozás (D = –0,35), azonnali verbális memória (D = –0,30), munkamemória (D = –0,27) és a végrehajtó funkcióknál (D = –0,26). A felnőtt 2-es típusú cukorbetegek teljesítménye gyengébb volt, mint a kontrolloké a munkamemória kivételével (D = +0,03) az összes kognitív területen. Legmagasabb hatásméretet az azonnali verbális memória (D = –1,12), pszichomotoros aktivitás (D = –0,82) és a késleltetett verbális memória (D = –0,81) mutatott. Közepes volt a hatásméret az általános intellektuális képességek (D = –0,68) területén, míg kicsi volt a hatásméret az általános memória (D = –0,37), a figyelem (D = –0,35), nyelv (D = –0,35), vizuális feldolgozás (D = –0,33) és a végrehajtó funkciók (D = –0,33) terén. Következtetés: Mindkét típusú cukorbetegség csökkent teljesítménnyel társul számos kognitív területen. Orv. Hetil., 2013, 154, 694–699.

  13. Adolescent sexuality and disability.

    PubMed

    Neufeld, Jacob A; Klingbeil, Fred; Bryen, Diane Nelson; Silverman, Brett; Thomas, Anila

    2002-11-01

    also include ways to create satisfying relationships. For more information about sex education as it relates to people with disabilities, the following abbreviated resource list may be helpful: http://www.sexualhealth.com http://www.lookingglass.com Ludwig S, Hingsburger, D. Being sexual: an illustrated series on sexuality and relationships. SIECCAN, 850 Coxwell, Aven., East York, Ontario, M4C 5R1 Tel: 416-466-5304; Fax: 416-778-0785. Sexuality Information and Education Council of the United States (SIECUS), 130 West 42nd Street, Suite 350, New York, NY 10036. Tel: 212-819-9770. National Information Center for Children and Youth with Disabilities (NICHCY), P.O. Box 1492, Washington, DC 20013; Tel/TTY: 800-695-0285; Fax: 202-884-8641; Internet: www.nichcy.org Non-Latex Supplies (Ask your pharmacist if not available) Trojan-Supra: http://www.trojancondoms.com Durex-Avanti: http://www.durex.com Female Health Company-FC Female Condom http://www.femalehealth.com Pasante--EzOn http://www.postalcondoms.co.uk (available in Canada and U.K.).

  14. Processes Influencing Ozone Levels in Alaskan Forest Fires Plumes during Long-Range Transport over the North Atlantic

    NASA Technical Reports Server (NTRS)

    Real, E.; Law, K. S.; Wienzierl, B.; Fiebig, M.; Petzold, A.; Wild, O.; Methven, J.; Arnold, S.; Stohl, A.; Huntrieser, H.; Roiger, A.; Schlager, H.; Stewart, D.; Avery, M.; Sachse, G.; Browell, E.; Ferrare, R.; Blake, D.

    2006-01-01

    A case of long-range transport of a biomass burning plume from Alaska to Europe is analyzed using a Lagrangian approach. This plume was sampled several times in the free troposphere over North America, the North Atlantic and Europe by 3 different aircraft during the IGAC Lagrangian 2K4 experiment which was part of the ICARTT/ITOP measurement intensive in summer 2004. Measurements in the plume showed enhanced values of CO, VOCs and NOy, mainly in form of PAN. Observed O3 levels increased by 17 ppbv over 5 days. A photochemical trajectory model, CiTTyCAT, is used to examine processes responsible for the chemical evolution of the plume. The model was initialized with upwind data, and compared with downwind measurements. The influence of high aerosol loading on photolysis rates in the plume is investigated using in-situ aerosol measurements in the plume and lidar retrievals of optical depth as input into a photolysis code (Fast-J), run in the model. Significant impacts on photochemistry are found with a decrease of 18 percent in O3 production and 24 percent in O3 destruction over 5 days when including aerosols. The plume is found to be chemically active with large O3 increases attributed primarily to PAN decomposition during descent of the plume towards Europe. The predicted O3 changes are very dependent on temperature changes during transport, and also, on water vapor levels in the lower troposphere which can lead to O3 destruction. Simulation of mixing/dilution was necessary to reproduce observed pollutants level in the plume. Mixing was simulated using background concentrations from measurements in air masses in close proximity to the plume, and mixing timescales (averaging 6.25 days) were derived from CO changes. Observed and simulated O3/CO correlations in the plume are also compared in order to evaluate the photochemistry in the model. Observed slopes changed from negative to positive over 5 days. This change, which can be attributed largely to photochemistry, is

  15. [Negative and positive predictive relationships between coping strategies and the three dimensions of burnout among Hungarian medical students].

    PubMed

    Ádám, Szilvia; Nistor, Anikó; Nistor, Katalin; Hazag, Anikó

    2014-08-10

    Bevezetés: Az orvostanhallgatók körében gyakori kiégés hatékony kezeléséhez és megelőzéséhez a kiégés és a stresszkezelő megküzdési stratégiák közötti kapcsolat ismerete elengedhetetlen, amelyről azonban kevés hazai adat áll rendelkezésre. Célkitűzés: A kiégés prevalenciájának és a megküzdési stratégiákkal való összefüggéseinek feltárása orvostanhallgatóknál. Módszer: Keresztmetszeti vizsgálat (N = 292), amelyben a kiégést a Maslach Kiégés-teszt Hallgatói Változatával, a megküzdési stratégiákat a Folkman–Lazarus-féle Konfliktusmegoldó Kérdőívvel és az egészségtudatos magatartásra vonatkozó kérdésekkel vizsgáltuk. A kiégés megküzdési stratégiákkal való kapcsolatát lineáris regresszióval tártuk fel. Eredmények: A magas szintű kiégés prevalenciája 25–56% volt. Míg a problémaközpontú megküzdési stratégiák és a segítségkérés egyenként a kimerülés és a cinizmus védőfaktorai, addig a hatékonyságcsökkenés kockázati tényezői voltak. Az érzelemközpontú megküzdési stratégiák a kimerülés és a cinizmus rizikó-, míg a hatékonyságcsökkenés védő tényezői voltak. Az egészségtudatos magatartás a kimerülés védő- és a hatékonyságcsökkenés kockázati faktora volt. Következtetések: A kiégés hatékony kezelése a legjellemzőbb kiégési dimenziót célzó megküzdési stratégiák alkalmazásával érhető el. Orv. Hetil., 2014, 155(32), 1273–1280.

  16. [Evaluation of thrombocytosis as predictive factor in colorectal cancer].

    PubMed

    Baranyai, Zsolt; Jósa, Valéria; Krzystanek, Marcin; Eklund, Aron C; Szász, A Marcell; Szállási, Zoltán

    2013-12-01

    Bevezetés/célkitűzés: A preoperatív thrombocytosist mint negatív prognosztikai markert több szolid tumorban igazolták. Azonban a colorectalis daganatok esetében a szakirodalom nem egységes. Vizsgálatunk célja annak megállapítása volt, hogy a thrombocytosis független rizikófaktora-e a metastasisképződésnek és a túlélésnek colorectalis daganatokban. Anyag és módszerek: A 2001 és 2011 közötti időszakból retrospektív módon 336 colorectalis tumor (CRC) és 118 colorectalis tumor eredetű májáttét (mCRC) miatt resecált beteg klinikopatológiai adatát gyűjtöttük ki. A thrombocytosist 400 G/l < vérlemezkeszámnál definiáltuk. A betegségmentes túlélést (DFS) és a teljes túlélést (OS) Kaplan–Meier- és log-rank módszerrel határoztuk meg. Eredmények: Mind a CRC-, mind a mCRC-csoportban az OS szignifikánsan rosszabb volt azoknál a betegeknél, akiknek emelkedett volt a vérlemezkeszámuk (HR = 2,2, p < 0,001 és HR = 2,9, p = 0,018). A többváltozós elemzés azt mutatta, hogy az emelkedett thrombocytaszám független prognosztikai faktor CRC-ben (HR = 1,7, p = 0,035) és mCRC-ben egyaránt (HR = 3,1, p = 0,017). A DFS szignifikánsan rosszabb volt a CRC-csoport azon betegeinél, akiknek magasabb volt a vérlemezkeszámuk (HR = 2,0, p = 0,011). Következtetések: A thrombocytaszám értékes és viszonylag olcsón elérhető prognosztikai faktor a túlélés vonatkozásában a CRC-ben és az mCRC-ben szenvedő betegeknél.

  17. [Evaluation of ambulatory antibiotic use in Hungary using drug-specific quality indicators].

    PubMed

    Matuz, Mária; Benkő, Ria; Hajdú, Edit; Viola, Réka; Soós, Gyöngyvér

    2013-06-16

    Bevezetés: A bakteriális rezisztencia visszaszorítására az antibiotikumok átgondolt alkalmazása lehetséges beavatkozási pont. Célkitűzés: A hazai ambuláns antibiotikum-alkalmazás gyakorlatának nemzetközi minőségi indikátorokon keresztül történő bemutatása. Módszer: Az 1996–2010 közötti időszakra vonatkozó nyers, nagykereskedői eladásokon alapuló, ambuláns szisztémás antibiotikum-felhasználási adatokat az Egészségügyi Világszervezet 2010. évi napi terápiás dózisai (defined daily dose – DDD) figyelembevételével DDD/1000 fő/nap egységben adták meg. Az antibiotikum-felhasználás értékelésére a nemzetközileg kidolgozott és validált minőségi indikátorokat alkalmazták. Eredmények: A hazai ambuláns antibiotikum-alkalmazás a vizsgálat során mennyiségileg kiegyenlített (18,0±1,8 DDD/1000 fő/nap) volt, szerkezetében azonban jelentős változások történtek. A széles versus szűk spektrumú béta-laktámok és makrolidek felhasználási aránya többszörösére nőtt (1996: 2,2 vs. 2010: 15,8), a fluorokinolonok felhasználása megháromszorozódott. A vizsgált tíz minőségi indikátor közül Magyarország három indikátor esetében az európai elithez, négy, valamint három esetében a gyengébb, illetve leggyengébb országok közé tartozott. Következtetés: A hazai ambuláns antibiotikum-felhasználás mennyiségileg a skandináv, az összetétel tekintetében a déli országokhoz hasonlít. Orv. Hetil., 2013, 154, 947–956.

  18. [Analysis of health insurance data on home nursing care in Hungary].

    PubMed

    Cs Horváth, Zoltán; Sebestyén, Andor; Molics, Bálint; Ágoston, István; Endrei, Dóra; Oláh, András; Betlehem, József; Imre, László; Bagosi, Gabriella; Boncz, Imre

    2014-04-13

    Bevezetés: Az otthoni szakápolás 1996 végén indult meg Magyarországon. Célkitűzés: A szerzők célja a magyar otthoni szakápolási rendszer egészségbiztosítási és igénybevételi mutatóinak bemutatása. Módszer: Az elemzésben szereplő adatok az Országos Egészségbiztosítási Pénztár finanszírozási adatbázisából (2001–2012) származnak. Elemezték a betegszámokat, a vizitszámokat, a szakápolási és szakirányú terápiás tevékenységek (gyógytorna, fizioterápia, logopédia) arányát. Eredmények: Az ellátott betegek száma a 2001. évi 36 560-ról 2012-re 51 647-re nőtt, 41,3%-kal emelkedett. A teljesített vizitek száma ugyanezen időszak alatt 841 715-ről 1 194 670-re, 41,9%-kal nőtt. A szakápolási és szakirányú terápiás tevékenységek, valamint az ápolási fokozatok vonatkozásában jelentős megyék közötti eltéréseket figyeltek meg. A szakápolásra kifizetett összegek aránya a legmagasabb volt Nógrád (80,4%), Szabolcs-Szatmár-Bereg (79,7%) és Komárom-Esztergom (74,6%) megyékben, míg a legalacsonyabb Zala (53,0%) és Csongrád (52,7%) megyékben, illetve Budapesten (47,9%). Következtetések: Az otthoni szakápolásban jelentős területi egyenlőtlenségek mutatkoznak, amelyek mérsékléséhez olyan szakmai irányelvek fejlesztésére van szükség, amelyek az otthoni szakápolás speciális vonatkozásait szabályozzák. Orv. Hetil., 2014, 155(15), 597–603.

  19. [Liquid-based cervical cytology ThinPrep screening in Hungary].

    PubMed

    Bak, Mihály; Séberné Éll, Mária; Bóka, Melinda; Veleczki, Zsuzsanna; Nyári, Tibor; Pete, Imre; Szentirmay, Zoltán

    2014-05-04

    Bevezetés: A hagyományos Papanicolaou-cervixkenetet világszerte az úgynevezett folyadékalapú (liquid-based) citológia váltotta fel. Egyértelműen bizonyított, hogy a folyadékalapú citológia alternatív módszer. Célkitűzés: A dolgozat célja a folyadékalapú méhnyakrákszűrés magyarországi eredményeinek, diagnózisainak követése, citohisztológiai összehasonlítása, illetve minőségbiztosítása volt. Módszer: 4573 folyadékalapú citológiai cervixkenetet a Bethesda (2001) beosztás szerint klasszifikálták. A humán papillomavírus tipizálását valós idejű polimeráz láncreakció módszerével határozták meg. Eredmények: A diagnózisok megoszlása: negatív 2323 (50,8%), egyéb, nem neoplasticus 2017 (44,1%) és kóros, neoplasticus 233 (5,1%). A nem értékelhető kenetek száma 43 (0,9%) volt, mérsékelt fokú intraepithelialis laesiót 87 esetben (1,9%), kifejezett fokú intraepithelialis laesiót 24 esetben (0,5%), carcinomát 23 esetben (0,5%) észleltek. A citológiai és hisztológiai leletek közötti korreláció alapján a módszer szenzitivitása 93,2%, specificitása 100%, pozitív prediktív értéke 100%-nak bizonyult. A folyadékalapú citológiai módszerrel a mérsékelt és kifejezett fokú intraepithelialis laesiót mutató kenetek aránya az előző évek azonos időtartamához viszonyítva 0,82%-ról 2,51%-ra emelkedett. Humán papillomavírus-DNS-meghatározást 81 esetben végeztek (pozitív prediktív érték 99%). Az 51 kóros hámelváltozás kapcsán 50 (98%) esetben igazolódott humán papillomavírus-fertőzés, ezek közül 20 (24,7%) alacsony, 46 (56,8%) pedig magas kockázatú volt. Következtetések: A szerzők megállapították, hogy tanulmányukban a folyadékalapú cervixcitológiai vizsgálat minőségbiztosítási eredményei megfelelnek a nemzetközileg elvártaknak. A folyadékalapú vizsgálat alternatív cervixcitológiai módszer, és hatékonysága, valamennyi paramétert tekintve

  20. [The "dress" makes the neuron -- different forms of the extracellular matrix in the central nervous system of vertebrates].

    PubMed

    Gáti, Georgina; Lendvai, Dávid

    2013-07-07

    Bevezetés: A központi idegrendszerben az idegsejtek, gliasejtek és azok nyúlványai közötti szűk teret extracelluláris mátrix veszi körül. Többkomponensű struktúra, amely a neuron és a glia közös terméke. Előfordulása, összetétele az idegrendszerben eltérő, ugyanakkor változékony is, mert a funkcionális változások a mátrix megjelenésében vagy éppen eltűnésében, átalakulásában jól követhetők. Az extracelluláris mátrix jellegzetes megjelenési formája, bizonyos típusú neuronok teste és proximalis dendritjei körül halmozódik fel. Az így létrejött struktúrát perineuronalis hálónak nevezzük. Ez az „öltözék” rendkívül fontos szerepet tölt be a sejtek védelmében, ionhomeosztázisuk megtartásában, a sejtmembrán receptorainak eloszlásában, illetve a sejtkapcsolatok biztosításában. Az extracelluláris mátrix újabban leírt formája az axonok végbunkói köré rakódik le, amelyet periaxonalis hüvelyeknek nevezünk. Célkitűzés: A szerzők arra kerestek választ, hogy az ember, a csirke és a patkány központi idegrendszerének eddig nem vizsgált területein a mátrix és az előbb említett megjelenési formái hogyan jelennek meg. Megvizsgálták, hogyan befolyásolja a filogenetikai státus a központi idegrendszeri mátrix ingerfüggő megjelenését és plaszticitását. Módszer: Két perfundált humán agy- és gerincvelőt, az Alzheimer-kórral kapcsolatos vizsgálatokra további 23 humán agymintát, 16 felnőttpatkány-agyvelőt és 18, különböző életkorú csirkeagyvelőt dolgoztak fel. Az extracelluláris mátrixot hisztokémiai és immunhisztokémiai festésekkel jelenítették meg. Eredmények: Az emberi hippocampusban azt találták, hogy a mátrixba ágyazott sejttestek és szinapszisok kevésbé pusztulnak degeneratív betegségben. Jellegzetes, csak a periszinaptikus régióra korlátozott mátrixot találtak az emberi látópályához kapcsolt külső t

  1. Astrobiology - The New Synthesis

    NASA Astrophysics Data System (ADS)

    Sik, A.; Simon, T.

    to let acids and alkalis into their cells. - Halophiles: these species are identified from salt lakes, salt mines and salt crystals (some of these are 250 million years old). The salt concentration of their cytoplasm is extreme high so the outer salt can not enter. 2. Extremophiles and evolution Jelentősek az extremofilek evolúciós evolution as- pects vonatkozásai, mivel igen sok ősbaktériumot archaea találunk közöttük. A hagyományos nézet, mely szerint az élővilág a baktériumok bacteria és eukar- ióták eukaryotes birodalmára osztható, a 70-es évek végén (Woese et al), 80-as évek elején (Fox et al) ingott meg, amikor a 16S rRNS (az élővilág egyik legkonz- ervatívabb molekuláris szerkezete molecular structure) összehasonlító szekvenciav- izsgálatai comparative sequence analysis alapján kiderült: az ősbaktériumok különválasztása a legmagasabb rendszertani taxonomy level szinten is indokolt, tehát külön birodalmat separate domain képeznek. Az eddigi genomtérképezések genome sequencing során kiderült, hogy az ősbaktériumok egyes génjei csak eukar- iótákban találhatók meg, nagyobb részük pedig teljesen egyedi [14]. Újabb elméletek szerint az eubaktériumok és ősbaktériumok közös őstől származ- nak, az eukarióták pedig az ősbaktériumokból fejlődhettek ki [15]. Az ősbaktériumok az egyetemes őshöz (LUCA - "last universal common ancestor") legközelebb álló élő kövületek living fossils lehetnek. Luca: az RNS-világ RNS world, a ribo-organizmusok ribo organisms utáni első orga- nizmus, amelyben már kialakult a fehérjék proteins és a DNS DNS mai szerepe. Az ősbaktériumok tanulmányozásával tehát a közel 4 milliárd évvel ezelőtti földi körülményekre következtethetünk. Az utóbbi években a földkéregben felfedezett gazdag extremofil-társulások alapján megdőlni látszik az a hagyományos nézet, mely szerint Luca egy meleg felszíni pocsolyában tenyészett, s divatoss