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Sample records for 8li optical potential

  1. The Initial State of Optically Polarized 8Li+ from the β-NMR in Bismuth

    NASA Astrophysics Data System (ADS)

    MacFarlane, W. A.; Levy, C. D. P.; Pearson, M. R.; Buck, T.; Chow, K. H.; Hariwal, A. N.; Kiefl, R. F.; McGee, F. H.; Morris, G. D.; Wang, D.

    2014-12-01

    Unlike the positive muon, β-NMR probe nuclei must be actively polarized. At the TRIUMF ISAC facility this is accomplished by in-flight collinear optical pumping with resonant circularly polarized laser light. This reliably produces a high degree of polarization, but the detailed state populations in the beam emerging from the optical polarizer are not well known. These populations are significant as they represent the initial state of the ensemble of probe spins implanted in a β-NMR experiment. Here we use the well-resolved quadrupolar split spectrum of 8Li+ in a high purity single crystal of bismuth to extract the sublevel populations under typical polarizer operating conditions, accounting for the spin relaxation in this semimetal.

  2. The {sup 9}Be({sup 8}Li,{sup 9}Be){sup 8}Li elastic-transfer reaction

    SciTech Connect

    Camargo, O.; Guimaraes, V.; Lichtenthaeler, R.; Scarduelli, V.; Kolata, J. J.; Bertulani, C. A.; Amro, H.; Becchetti, F. D.; Jiang Hao; Aguilera, E. F.; Lizcano, D.; Martinez-Quiroz, E.; Garcia, H.

    2008-09-15

    Angular distributions for the {sup 9}Be({sup 8}Li,{sup 9}Be){sup 8}Li elastic-transfer reaction have been measured with a 27-MeV {sup 8}Li radioactive nuclear beam. Spectroscopic factors for the <{sup 9}Be|{sup 8}Li+p> bound system were obtained from the comparison between the experimental differential cross sections and finite-range distorted-wave Born approximation calculations made with the code FRESCO. The spectroscopic factors so obtained are compared with shell-model calculations and other experimental values. Using the present value for the spectroscopic factors, cross sections and reaction rates for the {sup 8}Li(p,{gamma}){sup 9}Be direct proton-capture reaction of astrophysical interest were calculated in the framework of the potential model.

  3. Total reaction cross sections for 8Li + 90Zr at near-barrier energies

    NASA Astrophysics Data System (ADS)

    Pakou, A.; Pierroutsakou, D.; Mazzocco, M.; Acosta, L.; Aslanoglou, X.; Boiano, A.; Boiano, C.; Carbone, D.; Cavallaro, M.; Grebosz, J.; Keeley, N.; La Commara, M.; Manea, C.; Marquinez-Duran, G.; Martel, I.; Parascandolo, C.; Rusek, K.; Sánchez-Benítez, A. M.; Sgouros, O.; Signorini, C.; Soramel, F.; Soukeras, V.; Stiliaris, E.; Strano, E.; Torresi, D.; Trzcinska, A.; Watanabe, Y. X.; Yamaguchi, H.

    2015-05-01

    Total reaction cross sections for the radioactive nucleus 8Li on 90Zr are reported at the near-barrier energies of 18.5 and 21.5MeV, derived from quasi-elastic scattering measurements. An analysis of the quasi-elastic scattering results is performed within an optical model framework using the BDM3Y1 interaction and total reaction cross sections are deduced. These quantities, appropriately reduced, are compared with previous data obtained in elastic scattering measurements with well and weakly bound projectiles on various targets and a formula for predicting total reaction cross sections with an uncertainty of % is obtained. Further on, the ratios of direct to total reaction cross sections are estimated for 6,8Li on various targets and are compared with CDCC or CRC calculations. The energy dependence of the optical potential is also discussed.

  4. Neutron transfer reactions induced by {sup 8}Li on {sup 9}Be

    SciTech Connect

    Guimaraes, V.; Lichtenthaeler, R.; Camargo, O.; Barioni, A.; Assuncao, M.; Kolata, J. J.; Amro, H.; Becchetti, F. D.; Jiang, Hao; Aguilera, E. F.; Lizcano, D.; Martines-Quiroz, E.; Garcia, H.

    2007-05-15

    Angular distributions for the elastic scattering of {sup 8}Li on {sup 9}Be and the neutron transfer reactions {sup 9}Be({sup 8}Li,{sup 7}Li){sup 10}Be and {sup 9}Be({sup 8}Li,{sup 9}Li){sup 8}Be were measured with a 27 MeV {sup 8}Li radioactive nuclear beam. Spectr- oscopic factors for {sup 8}Li (multiply-in-circle sign)n{sup 9}Li and {sup 7}Li (multiply-in-circle sign)n{sup 8}Li bound systems were obtained from the comparison between the experimental differential cross section and finite-range distorted-wave Born approximation calculations with the code FRESCO. The spectroscopic factors obtained were compared to shell model calculations and to other experimental values from (d,p) reactions. Using the present values for the spectroscopic factor, cross sections for the direct neutron-capture reactions {sup 7}Li(n,{gamma}){sup 8}Li and {sup 8}Li(n,{gamma}){sup 9}Li were calculated in the framework of a potential model.

  5. ELECTRONIC STRUCTURE AND LINEAR OPTICAL PROPERTIES OF MIXED ALKALI-METAL BOROPHOSPHATES (LiK2BP2O8, Li3K2BP4O14): A FIRST-PRINCIPLES STUDY

    NASA Astrophysics Data System (ADS)

    Zhang, Bei; Jing, Qun; Yang, Zhihua; Wang, Ying; Su, Xin; Pan, Shilie; Zhang, Jun

    2013-07-01

    LiK2BP2O8 and Li3K2BP4O14 are synthesized by high-temperature solution method with the same elements, while contain different fundamental building units. Li3K2BP4O14 is a novel P-O-P linking structure which gives a rare example of violation of Pauling's fourth rule. The electronic structures of LiK2BP2O8 and Li3K2BP4O14 are investigated by density functional calculations. Direct gaps of 5.038 eV (LiK2BP2O8) and 5.487 eV (Li3K2BP4O14) are obtained. By analyzing the density of states (DOS) of LiK2BP2O8 and Li3K2BP4O14, the P-O-P linking in fundamental building units of Li3K2BP4O14 crystal is proved theoretically. Based on the electronic properties, the linear optical information is captured.

  6. 8Li({alpha},n)11B at Big Bang Temperatures: Neutron Counting With a Low Intensity 8Li Radioactive Beam

    SciTech Connect

    Cherubini, S.; Rolfs, C.; Strieder, F.; Figuera, P.; Agodi, C.; Alba, R.; Calabretta, L.; Cosentino, L.; Del Zoppo, A.; Di Pietro, A.; Lamia, L.; Pappalardo, L.; Pizzone, R.G.; Musumarra, A.; Pellegriti, M.G.; Rinollo, A.; Romano, S.; Spitaleri, C.; Tudisco, S.; Tumino, A.

    2004-02-27

    The cross section of 8Li({alpha},n)11B is very important for the study of primordial nucleosinthesys models. In this paper we report on the production of a 8Li beam via the 7Li(d,p)8Li reaction at the Laboratori Nazionali del Sud. Also, a novel experimental technique for measuring the reaction 8Li({alpha},n)11B at energies of astrophysical interest has been implemented and tested.

  7. Shell model study on the astrophysical neutron capture of 8Li

    NASA Astrophysics Data System (ADS)

    Ma, Hai-Liang; Dong, Bao-Guo; Yan, Yu-Liang; Zhang, Xi-Zhen

    2012-09-01

    The astrophysical important neutron capture of 8Li is investigated by combining the shell model and potential model. Three effective interactions, SFO, PSDMK2 and PSDWBP are used to calculate the spectroscopic factors and reaction widths. For the resonant capture from 8Li to the first continuum state of 9Li , the three effective interactions give similar neutron partial widths, and they are well compared with the experimental results. However, the calculated photon widths are over 5 times less than the previous estimate. This will make the substantial difference that, at high temperature, the direct capture mechanism still dominates. The calculated capture rates generally agree well with the experimental data. The uncertainty of calculated cross-sections and capture rates mainly results from the different prediction of spectroscopic factors for the three effective interactions. The total neutron capture rates in our calculations are less than 4300 cm3 mole-1 s-1 for T 9 < 5 which confirms that the main reaction flow will proceed through the reaction 8Li ( α, n) 11B in the stellar environments.

  8. The electrochemical behaviors of Mg-8Li-3Al-0.5Zn and Mg-8Li-3Al-1.0Zn in sodium chloride solution

    NASA Astrophysics Data System (ADS)

    Lv, Yanzhuo; Liu, Min; Xu, Yan; Cao, Dianxue; Feng, Jing

    2013-03-01

    The electrochemical oxidation behaviors of Mg-8Li-3Al-0.5Zn and Mg-8Li-3Al-1.0Zn electrodes in 0.7 mol L-1 NaCl solution are investigated by methods of potentiodynamic polarization, potentiostatic oxidation, electrochemical impedance spectroscopy and scanning electron microscopy. The phase composition of Mg-8Li-3Al-0.5Zn and Mg-8Li-3Al-1.0Zn alloys is analyzed conducted by X-ray diffraction. The performances of Mg-8Li-3Al-0.5Zn and Mg-8Li-3Al-1.0Zn as the anode of Mg-H2O2 semi fuel cells are determined. The effect of Zn content on the corrosion resistant of these Mg-Li-based alloys is studied. It is found that the Mg-8Li-3Al-0.5Zn electrode has higher discharge activity and less corrosion resistance than that of Mg-8Li-3Al-1.0Zn electrode in 0.7 mol L-1 NaCl solution. The Mg-H2O2 semi fuel cell with Mg-8Li-3Al-0.5Zn anode presents a maximum power density of 100 mW cm-2 at room temperature, which is higher than that of Mg-8Li-3Al-1.0Zn anode (80 mW cm-2). The performance of semi fuel cell with the Mg-8Li-3Al-0.5Zn electrode is better than that with Mg-8Li-3Al-1.0Zn electrode, especially at higher current density (>30 mA cm-2).

  9. Pion-deuteron optical potential

    NASA Astrophysics Data System (ADS)

    Afnan, I. R.; Stelbovics, A. T.

    1981-02-01

    The three-body approach to the single-scattering optical potential proposed by Tandy, Redish, and Bollé is tested in the context of π-d scattering where the various approximations are compared with the exact solution of the Faddeev equations. For π-d scattering we find that the integral equations derived for the Kerman-McManus-Thaler form of the single-scattering optical potential are markedly superior to those of the Watson form. Our analysis includes a study of the convergence properties of the various multiple-scattering series encountered. NUCLEAR REACTIONS π-d optical potential; TRB, KMT, and Watson multiple-scattering series; Faddeev solution comparison.

  10. β-detected nuclear quadrupole resonance and relaxation of 8Li+ in sapphire

    NASA Astrophysics Data System (ADS)

    Salman, Z.; Chow, K. H.; Hossain, M. D.; Kiefl, R. F.; Levy, C. D. P.; Parolin, T. J.; Pearson, M. R.; Saadaoui, H.; Wang, D.; MacFarlane, W. A.

    2014-12-01

    We report detailed behaviour of low energy 8Li implanted near the surface of α- Al2O3 single crystal, as revealed by beta-detected NQR of 8Li. We find that the implanted 8Li occupies at least two sites with non-cubic symmetry in the Al2O3 lattice. In both sites the 8Li experiences axially symmetric electric field gradient, with the main principal axis along the c-crystallographic direction. The temperature and field dependence of the spin lattice relaxation of 8Li in α-Al2O3, indicate that the 8Li diffusion is negligible on the scale of its lifetime, 1.21 s.

  11. Non-local Optical Potentials

    NASA Astrophysics Data System (ADS)

    Thompson, Ian

    2010-11-01

    In all direct reactions to probe the structure of exotic nuclei at FRIB, optical potentials will be needed in the entrance and exit channels. At high energies Glauber approximations may be useful, but a low energies (5 to 20 MeV/nucleon) other approaches are required. Recent work of the UNEDF project [1] has shown that reaction cross sections at these energies can be accounted for by calculating all inelastic and transfer channels reachable by one particle-hole transitions from the elastic channel. In this model space, we may also calculate the two-step dynamic polarization potential (DPP) that adds to the bare folded potential to form the complex optical potential. Our calculations of the DPP, however, show that its non-localities are very significant, as well as the partial-wave dependence of both its real and imaginary components. The Perey factors (the wave function ratio to that from an equivalent local potential) are more than 20% different from unity, especially for partial waves inside grazing. These factors combine to suggest a reexamination of the validity of local and L-independent fitted optical potentials, especially for capture reactions that are dominated by low partial waves. Prepared by LLNL under Contract DE-AC52-07NA27344. [1] G.P.A. Nobre, F.S. Dietrich, J.E. Escher, I.J. Thompson, M. Dupuis, J. Terasaki and J. Engel, submitted to Phys. Rev. Letts., 2010.

  12. Optical potential from first principles

    DOE PAGES

    Rotureau, J.; Danielewicz, P.; Hagen, G.; ...

    2017-02-15

    Here, we develop a method to construct a microscopic optical potential from chiral interactions for nucleon-nucleus scattering. The optical potential is constructed by combining the Green’s function approach with the coupled-cluster method. To deal with the poles of the Green’s function along the real energy axis we employ a Berggren basis in the complex energy plane combined with the Lanczos method. Using this approach, we perform a proof-of-principle calculation of the optical potential for the elastic neutron scattering on 16O. For the computation of the ground-state of 16O, we use the coupled-cluster method in the singles-and-doubles approximation, while for themore » A ±1 nuclei we use particle-attached/removed equation-of-motion method truncated at two-particle-one-hole and one-particle-two-hole excitations, respectively. We verify the convergence of the optical potential and scattering phase shifts with respect to the model-space size and the number of discretized complex continuum states. We also investigate the absorptive component of the optical potential (which reflects the opening of inelastic channels) by computing its imaginary volume integral and find an almost negligible absorptive component at low-energies. To shed light on this result, we computed excited states of 16O using equation-of-motion coupled-cluster method with singles-and- doubles excitations and we found no low-lying excited states below 10 MeV. Furthermore, most excited states have a dominant two-particle-two-hole component, making higher-order particle-hole excitations necessary to achieve a precise description of these core-excited states. We conclude that the reduced absorption at low-energies can be attributed to the lack of correlations coming from the low-order cluster truncation in the employed coupled-cluster method.« less

  13. Optical potential from first principles

    NASA Astrophysics Data System (ADS)

    Rotureau, J.; Danielewicz, P.; Hagen, G.; Nunes, F. M.; Papenbrock, T.

    2017-02-01

    We develop a method to construct a microscopic optical potential from chiral interactions for nucleon-nucleus scattering. The optical potential is constructed by combining the Green's function approach with the coupled-cluster method. To deal with the poles of the Green's function along the real energy axis we employ a Berggren basis in the complex energy plane combined with the Lanczos method. Using this approach, we perform a proof-of-principle calculation of the optical potential for the elastic neutron scattering on 16O. For the computation of the ground state of 16O, we use the coupled-cluster method in the singles-and-doubles approximation, while for the A ±1 nuclei we use particle-attached/removed equation-of-motion method truncated at two-particle-one-hole and one-particle-two-hole excitations, respectively. We verify the convergence of the optical potential and scattering phase shifts with respect to the model-space size and the number of discretized complex continuum states. We also investigate the absorptive component of the optical potential (which reflects the opening of inelastic channels) by computing its imaginary volume integral and find an almost negligible absorptive component at low energies. To shed light on this result, we computed excited states of 16O using the equation-of-motion coupled-cluster method with singles-and-doubles excitations and we found no low-lying excited states below 10 MeV. Furthermore, most excited states have a dominant two-particle-two-hole component, making higher-order particle-hole excitations necessary to achieve a precise description of these core-excited states. We conclude that the reduced absorption at low energies can be attributed to the lack of correlations coming from the low-order cluster truncation in the employed coupled-cluster method.

  14. Structure of 8Li from a reaction cross-section measurement

    NASA Astrophysics Data System (ADS)

    Fan, G. W.; Fukuda, M.; Nishimura, D.; Cai, X. L.; Fukuda, S.; Hachiuma, I.; Ichikawa, C.; Izumikawa, T.; Kanazawa, M.; Kitagawa, A.; Kuboki, T.; Lantz, M.; Mihara, M.; Nagashima, M.; Namihira, K.; Ohkuma, Y.; Ohtsubo, T.; Ren, Zhongzhou; Sato, S.; Shen, Z. Q.; Sugiyama, M.; Suzuki, S.; Suzuki, T.; Takechi, M.; Yamaguchi, T.; Xu, B. J.; Xu, W.

    2014-10-01

    We have precisely measured reaction cross sections (σR) for 8Li using 9Be, 12C , 27Al, and proton targets at intermediate energies by the transmission method. From the energy dependence of the σR including the high energy data, the density distribution of 8Li was deduced through a modified Glauber model. It is shown that 8Li has a shorter tail structure in the density as compared with that of 8B and the matter radius of 8Li is similar to those of the other nonhalo Li isotopes. The result is consistent with the previous experiments that there is a tendency for 8Li to be a skin nucleus.

  15. Determining the 7Li(n,γ) cross section via Coulomb dissociation of 8Li

    NASA Astrophysics Data System (ADS)

    Izsák, R.; Horváth, Á.; Kiss, Á.; Seres, Z.; Galonsky, A.; Bertulani, C. A.; Fülöp, Zs.; Baumann, T.; Bazin, D.; Ieki, K.; Bordeanu, C.; Carlin, N.; Csanád, M.; Deák, F.; DeYoung, P.; Frank, N.; Fukuchi, T.; Gade, A.; Galaviz, D.; Hoffman, C. R.; Peters, W. A.; Schelin, H.; Thoennessen, M.; Veres, G. I.

    2013-12-01

    The applicability of Coulomb dissociation reactions to determine the cross section for the inverse neutron capture reaction was explored using the reaction 8Li(γ,n)7Li. A 69.5 MeV/nucleon 8Li beam was incident on a Pb target, and the outgoing neutron and 7Li nucleus were measured in coincidence. The deduced (n,γ) excitation function is consistent with data for the direct capture reaction 7Li(n,γ)8Li and with low-energy effective field theory calculations.

  16. Optical Potential Field Mapping System

    NASA Technical Reports Server (NTRS)

    Reid, Max B. (Inventor)

    1996-01-01

    The present invention relates to an optical system for creating a potential field map of a bounded two dimensional region containing a goal location and an arbitrary number of obstacles. The potential field mapping system has an imaging device and a processor. Two image writing modes are used by the imaging device, electron deposition and electron depletion. Patterns written in electron deposition mode appear black and expand. Patterns written in electron depletion mode are sharp and appear white. The generated image represents a robot's workspace. The imaging device under processor control then writes a goal location in the work-space using the electron deposition mode. The black image of the goal expands in the workspace. The processor stores the generated images, and uses them to generate a feedback pattern. The feedback pattern is written in the workspace by the imaging device in the electron deposition mode to enhance the expansion of the original goal pattern. After the feedback pattern is written, an obstacle pattern is written by the imaging device in the electron depletion mode to represent the obstacles in the robot's workspace. The processor compares a stored image to a previously stored image to determine a change therebetween. When no change occurs, the processor averages the stored images to produce the potential field map.

  17. Nucleon Optical Potential in Brueckner Theory

    SciTech Connect

    Haider, Wasi

    2008-10-13

    Recent results of g-matrix calculation of the nucleon optical potential are presented and their predictions are compared with experimental data for Sn-isotopes. Corrections to spin-orbit part of the potential are discussed. Extension of Bethe's method to calculate three nucleon interaction effects in the nucleon optical potential is presented.

  18. THE REACTION {sup 8}Li(n,γ){sup 9}Li AT ASTROPHYSICAL ENERGIES AND ITS ROLE IN PRIMORDIAL NUCLEOSYNTHESIS

    SciTech Connect

    Dubovichenko, S. B.; Dzhazairov-Kakhramanov, A. V. E-mail: albert-j@yandex.ru

    2016-03-01

    The possibility of describing available experimental data for the total cross sections of neutron radiative capture on {sup 8}Li at thermal and astrophysical energies was considered within the framework of the modified potential cluster model with the state classification of nuclear particles according to the Young tableaux. Our approach allows one to transmit available data in the energy range 0.1–1.0 MeV quite well, and predicts the behavior of the total cross sections at super-low energies, down to 25.3 × 10{sup −9} MeV.

  19. Excited states in ^9Li from d(^8Li,p)^9Li

    NASA Astrophysics Data System (ADS)

    Rehm, K. E.; Greene, J. P.; Henderson, D. J.; Janssens, R. V. F.; Jiang, C. L.; Moore, E. F.; Pardo, R. C.; Peterson, D.; Pieper, S. C.; Savard, G.; Schiffer, J. P.; Sinha, S.; Tang, X.; Wiringa, R. W.; Wuosmaa, A. H.; Jisonna, L.; Segel, R. E.; Paul, M.

    2004-10-01

    We have studied levels in ^9Li from the d(^8Li,p)^9Li reaction using an unstable ^8Li beam produced at the ATLAS "in-flight" production facility at Argonne National Laboratory. The ^8Li beam bombarded a solid CD2 target. Protons from the d(^8Li,p)^9Li reaction were detected at backward angles in the laboratory using segmented silicon detectors, in coincidence with forward scattered ^7,8,9Li ions. The neutron spectroscopic factors determined from the d(^8Li,p)^9Li reaction can be used as a sensitive test for modern calculations of the structure of ^9Li. Experimental proton angular distributions for low-lying levels in ^9Li will be presented and compared with theoretical predictions. Work Supported by the U. S. DOE, Office of Nuclear Physics, Contract numbers W-31-109-ENG-38 (ANL), DE-FG02-04R41320 (WMU) and DE-FG02-98ER4106 (NWU), and the Faculty Research and Creative Activities Fund, Western Michigan University (WMU).

  20. Perspective and potential of smart optical materials

    NASA Astrophysics Data System (ADS)

    Choi, Sang H.; Duzik, Adam J.; Kim, Hyun-Jung; Park, Yeonjoon; Kim, Jaehwan; Ko, Hyun-U.; Kim, Hyun-Chan; Yun, Sungryul; Kyung, Ki-Uk

    2017-09-01

    The increasing requirements of hyperspectral imaging optics, electro/photo-chromic materials, negative refractive index metamaterial optics, and miniaturized optical components from micro-scale to quantum-scale optics have all contributed to new features and advancements in optics technology. Development of multifunctional capable optics has pushed the boundaries of optics into new fields that require new disciplines and materials to maximize the potential benefits. The purpose of this study is to understand and show the fundamental materials and fabrication technology for field-controlled spectrally active optics (referred to as smart optics) that are essential for future industrial, scientific, military, and space applications, such as membrane optics, filters, windows for sensors and probes, telescopes, spectroscopes, cameras, light valves, light switches, and flat-panel displays. The proposed smart optics are based on the Stark and Zeeman effects in materials tailored with quantum dot arrays and thin films made from readily polarizable materials via ferroelectricity or ferromagnetism. Bound excitonic states of organic crystals are also capable of optical adaptability, tunability, and reconfigurability. To show the benefits of smart optics, this paper reviews spectral characteristics of smart optical materials and device technology. Experiments testing the quantum-confined Stark effect, arising from rare earth element doping effects in semiconductors, and applied electric field effects on spectral and refractive index are discussed. Other bulk and dopant materials were also discovered to have the same aspect of shifts in spectrum and refractive index. Other efforts focus on materials for creating field-controlled spectrally smart active optics on a selected spectral range. Surface plasmon polariton transmission of light through apertures is also discussed, along with potential applications. New breakthroughs in micro scale multiple zone plate optics as a micro

  1. Studying {sup 12}B via {sup 8}Li-{alpha} resonant scattering

    SciTech Connect

    Torresi, D.; Lattuada, M.; Pellegriti, M. G.; Strano, E.; Cosentino, L.; Di Pietro, A.; Figuera, P.; Maiolino, C.; Santonocito, D.; Scalia, G.; Ducoin, C.; Papa, M.; Fisichella, M.; Lonnroth, T.; Musumarra, A.; Rovituso, M.; Scuderi, V.; Zadro, M.

    2011-10-28

    The inverse kinematics thick target scattering method (TTIK) has been used to study the {sup 8}Li elastic scattering on {sup 4}He in order to investigate {sup 8}Li-{alpha} cluster configurations in excited states of {sup 12}B. A {sup 8}Li beam, provided by the radioactive beam facility EXCYT, at E{sub beam} = 30.6 MeV, passing through helium thick target, continuously decreases its energy inducing elastic scattering starting from the initial energy down to zero. Four {Delta}E-E double stage silicon detector telescopes were used to detect the recoil {alpha}-particles coming from the scattering. Event by event time measurement between beam particles passing through a MCP detector and {alpha}-particles impinging on {Delta}E stage allows elastic from inelastic events discrimination, thus representing an improvement of the TTIK method. In this paper the used experimental technique and some preliminary results will be briefly described.

  2. Measurement of the 8Li( α, n) 11B reaction cross sections of astrophysical interest

    NASA Astrophysics Data System (ADS)

    Hashimoto, T.; Ishikawa, T.; Kawamura, T.; Nakai, K.; Ishiyama, H.; Watanabe, Y. X.; Miyatake, H.; Tanaka, M. H.; Yoshikawa, N.; Jeong, S. C.; Fuchi, Y.; Katayama, I.; Nomura, T.; Das, S. K.; Saha, P. K.; Fukuda, T.; Nishio, K.; Mitsuoka, S.; Ikezoe, H.; Matsuda, M.; Ichikawa, S.; Furukawa, T.; Izumi, H.; Shimoda, T.; Mizoi, Y.; Terasawa, M.

    2004-12-01

    An accurate exclusive measurement of the 8Li( α, n) 11B reaction cross sections has been carried out successfully by using a highly efficient detector system and high-purity low energy 8Li-beam. The excitation function obtained with high statistics in the energy region from 0.9 to 2.7 MeV in the center-of-mass system is reported. The present cross sections show that the averaged ratio of total cross section to the inverted neutron capture cross section is 4 ˜ 5. Some details of the experimental method are also described.

  3. Optically-induced-potential-based image encryption.

    PubMed

    Chen, Bing-Chu; Wang, He-Zhou

    2011-11-07

    We present a technique of nonlinear image encryption by use of virtual optics. The image to be encrypted is superposed on a random intensity image. And this superposed image propagates through a nonlinear medium and a 4-f system with single phase key. The image is encrypted to a stationary white noise. The decryption process is sensitive to the parameters of the encryption system and the phase key in 4-f system. This sensitivity makes attackers hard to access the phase key. In nonlinear medium, optically-induced potentials, which depend on intensity of optical wave, make the superposition principle frustrated. This nonlinearity based on optically induced potentials highly improves the secrecy level of image encryption. Resistance against attacks based on the phase retrieval technique proves that it has the high secrecy level. This nonlinear image encryption based on optically induced potentials is proposed and demonstrated for the first time.

  4. Radiative 8Li(n, γ)9Li Capture at Low Energies

    NASA Astrophysics Data System (ADS)

    Dubovichenko, S. B.

    2017-01-01

    Within the framework of the modified cluster model with forbidden states and classification of states according to the Young tableaux, the possibility is considered of describing the available experimental data for the total cross sections of n8Li capture at thermal and astrophysical energies.

  5. Radiative 8Li( n, γ)9Li Capture at Low Energies

    NASA Astrophysics Data System (ADS)

    Dubovichenko, S. B.

    2017-01-01

    Within the framework of the modified cluster model with forbidden states and classification of states according to the Young tableaux, the possibility is considered of describing the available experimental data for the total cross sections of n8Li capture at thermal and astrophysical energies.

  6. Microscopic optical buffering in a harmonic potential

    PubMed Central

    Sumetsky, M.

    2015-01-01

    In the early days of quantum mechanics, Schrödinger noticed that oscillations of a wave packet in a one-dimensional harmonic potential well are periodic and, in contrast to those in anharmonic potential wells, do not experience distortion over time. This original idea did not find applications up to now since an exact one-dimensional harmonic resonator does not exist in nature and has not been created artificially. However, an optical pulse propagating in a bottle microresonator (a dielectric cylinder with a nanoscale-high bump of the effective radius) can exactly imitate a quantum wave packet in the harmonic potential. Here, we propose a tuneable microresonator that can trap an optical pulse completely, hold it as long as the material losses permit, and release it without distortion. This result suggests the solution of the long standing problem of creating a microscopic optical buffer, the key element of the future optical signal processing devices. PMID:26689546

  7. Skin optical clearing potential of disaccharides

    NASA Astrophysics Data System (ADS)

    Feng, Wei; Shi, Rui; Ma, Ning; Tuchina, Daria K.; Tuchin, Valery V.; Zhu, Dan

    2016-08-01

    Skin optical clearing can significantly enhance the ability of biomedical optical imaging. Some alcohols and sugars have been selected to be optical clearing agents (OCAs). In this work, we paid attention to the optical clearing potential of disaccharides. Sucrose and maltose were chosen as typical disaccharides to compare with fructose, an excellent monosaccharide-OCA, by using molecular dynamics simulation and an ex vivo experiment. The experimental results indicated that the optical clearing efficacy of skin increases linearly with the concentration for each OCA. Both the theoretical predication and experimental results revealed that the two disaccharides exerted a better optical clearing potential than fructose at the same concentration, and sucrose is optimal. Since maltose has an extremely low saturation concentration, the other two OCAs with saturation concentrations were treated topically on rat skin in vivo, and optical coherence tomography imaging was applied to monitor the optical clearing process. The results demonstrated that sucrose could cause a more significant increase in imaging depth and signal intensity than fructose.

  8. Corrosion behavior of as-cast Mg-8Li-3Al+ xCe alloy in 3.5wt% NaCl solution

    NASA Astrophysics Data System (ADS)

    Manivannan, S.; Dinesh, P.; Mahemaa, R.; MariyaPillai, Nandhakumaran; Kumaresh Babu, S. P.; Sundarrajan, Srinivasan

    2016-10-01

    Mg-8Li-3Al+ xCe alloys ( x = 0.5wt%, 1.0wt%, and 1.5wt%) were prepared through a casting route in an electric resistance furnace under a controlled atmosphere. The cast alloys were characterized by X-ray diffraction, optical microscopy, scanning electron microscopy, and energy-dispersive X-ray spectroscopy. The corrosion behavior of the as-cast Mg-8Li-3Al+ xCe alloys were studied under salt spray tests in 3.5wt% NaCl solution at 35°C, in accordance with standard ASTM B-117, in conjunction with potentiodynamic polarization (PDP) tests. The results show that the addition of Ce to Mg-8Li-3Al (LA83) alloy results in the formation of Al2Ce intermetallic phase, refines both the α-Mg phase and the Mg17Al12 intermetallic phase, and then increases the microhardness of the alloys. The results of PDP and salt spray tests reveal that an increase in Ce content to 1.5wt% decreases the corrosion rate. The best corrosion resistance is observed for the LA83 alloy sample with 1.0wt% Ce.

  9. Reactions with 8Li at RIBRAS (Radioactive Ion Beams in Brasil): Astrophysical and nuclear structure applications

    NASA Astrophysics Data System (ADS)

    Mendes, D. R., Jr.; Lépine-Szily, A.; Descouvemont, P.

    2012-02-01

    We present the results of the 8Li(p, α) 5He reaction of astrophysical interest, measured at the RIBRAS system. It was realized in inverse kinematics and using a thick CH2 polyethylene target. Using the thick target method the complete excitation function could be measured between Ecm = 0.2-2.5 MeV, which includes the Gamow peak energy region. The contribution of contaminating 12C(8Li,4He) 16N and 12C(7Li, 4He) 15N reactions is still under analysis. However, if the cross section is expected to be somewhat reduced, the subtraction of the contamination will not change the general feature of the excitation function.

  10. Beta-ray angular distributions of spin aligned 8Li and 8B

    NASA Astrophysics Data System (ADS)

    Sumikama, T.; Iwakoshi, T.; Nagatomo, T.; Ogura, M.; Nakashima, Y.; Fujiwara, H.; Matsuta, K.; Minamisono, T.; Mihara, M.; Fukuda, M.; Minamisono, K.; Yamaguchi, T.

    2004-12-01

    The alignment correlation terms in the β-ray angular distributions from spin aligned 8Li and 8B have been measured precisely. The difference of these terms between the mirror pair is compared with the prediction. As a result, the G-parity violating induced tensor term is found to be small. The significant contribution from the second-forbidden matrix elements is shown by comparing with the β- α correlation coefficients.

  11. Distinguishing magnetic vs. quadrupolar relaxation in b-NMR using 8Li and 9Li

    NASA Astrophysics Data System (ADS)

    Chatzichristos, A.; McFadden, R. M. L.; Karner, V. L.; Cortie, D. L.; Fang, A.; Levy, C. D. P.; Macfarlane, W. A.; Morris, G. D.; Pearson, M. R.; Salman, Z.; Kiefl, R. F.

    2016-09-01

    Beta-detected NMR is a powerful technique in condensed matter physics. It uses the parity violation of beta decay to detect the NMR signal from a beam of highly polarized radionuclides implanted in a sample material. Spin-lattice relaxation (SLR) is studied by monitoring the rate with which the asymmetry between the beta counts in two opposing detectors is lost. Unlike classical NMR, b-NMR can study thin films and near-surface effects. The most common b-NMR isotope at TRIUMF is 8Li, which has a quadrupole moment, thus it is sensitive to both magnetic fields and electric field gradients. A challenge with 8Li b-NMR is identifying the predominant mechanism of SLR in a given sample. It is possible to distinguish between SLR mechanisms by varying the probe isotope. For two isotopes with different nuclear moments, the ratio of SLR rates should be different in the limits of either pure magnetic or quadrupolar relaxation. This method has been used in classical NMR and we report its first application to b-NMR. We measured the SLR rates for 8Li and 8Li in Pt foil and SrTiO3. Pt is a test case for pure magnetic relaxation. SrTiO3 is a non-magnetic insulator, but the source of its relaxation is not well understood. Here we show that its relaxation is mainly quadrupolar. We thank TRIUMF's CMMS for their technical support. This work was supported by: NSERC Discovery Grants to R.F.K. and W.A.M.; and IsoSiM fellowships to A.C. and R.M.L.M.

  12. A Brief Survey of β-Detected NMR of Implanted 8Li+ in Organic Polymers

    NASA Astrophysics Data System (ADS)

    McGee, F. H.; McKenzie, I.; Buck, T.; Daley, C. R.; Forrest, J. A.; Harada, M.; Kiefl, R. F.; Levy, C. D. P.; Morris, G. D.; Pearson, M. R.; Sugiyama, J.; Wang, D.; MacFarlane, W. A.

    2014-12-01

    Unlike the positive muon, we expect the chemistry of the implanted 8Li+β-NMR probe in organic polymers to be simply that of the monovalent ion, but almost nothing is known about the NMR of isolated Li+ in this context. Here, we present a brief survey of 8Li+β-NMR in a variety of insulating polymers at high magnetic field, including polyimide, PET, polycarbonate, polystyrene and polyethylene oxide. In all cases, we find a large-amplitude, broad Lorentzian resonance near the Larmor frequency, consistent with the expected diamagnetic charge state. We also find remarkably fast spin-lattice relaxation rates 1/T1. There is very little dependence of either linewidth or 1/T1 on the proton density, the main source of nuclear dipolar magnetic fields, leading us to conclude the main contribution to both broadening and spin relaxation at room temperature is quadrupolar in origin. This behaviour is very different from crystalline insulators such as MgO and Al2O3, and suggests that 8Li+β-NMR will be an important probe of polymer dynamics. Additionally, we note dramatically different behaviour of one sample above its glass transition, motivating the construction of a high temperature spectrometer to enable further exploration at elevated temperature.

  13. The optical potential on the lattice

    NASA Astrophysics Data System (ADS)

    Agadjanov, Dimitri; Döring, Michael; Mai, Maxim; Meißner, Ulf-G.; Rusetsky, Akaki

    2016-06-01

    The extraction of hadron-hadron scattering parameters from lattice data by using the Lüscher approach becomes increasingly complicated in the presence of inelastic channels. We propose a method for the direct extraction of the complex hadron-hadron optical potential on the lattice, which does not require the use of the multi-channel Lüscher formalism. Moreover, this method is applicable without modifications if some inelastic channels contain three or more particles.

  14. The optical potential on the lattice

    SciTech Connect

    Agadjanov, Dimitri; Doring, Michael; Mai, Maxim; MeiBner, Ulf -G.; Rusetsky, Akaki

    2016-06-08

    The extraction of hadron-hadron scattering parameters from lattice data by using the Luscher approach becomes increasingly complicated in the presence of inelastic channels. We propose a method for the direct extraction of the complex hadron-hadron optical potential on the lattice, which does not require the use of the multi-channel Luscher formalism. Furthermore, this method is applicable without modifications if some inelastic channels contain three or more particles.

  15. The optical potential on the lattice

    DOE PAGES

    Agadjanov, Dimitri; Doring, Michael; Mai, Maxim; ...

    2016-06-08

    The extraction of hadron-hadron scattering parameters from lattice data by using the Luscher approach becomes increasingly complicated in the presence of inelastic channels. We propose a method for the direct extraction of the complex hadron-hadron optical potential on the lattice, which does not require the use of the multi-channel Luscher formalism. Furthermore, this method is applicable without modifications if some inelastic channels contain three or more particles.

  16. Searching for Tensor Currents in the Weak Interaction Using 8Li β Decay

    NASA Astrophysics Data System (ADS)

    Burkey, M. T.; Savard, G.; Segel, R. E.; Clark, J. A.; Scielzo, N. D.; Gallant, A. T.; Kolos, K.; Padgett, S. W.; Wang, B. S.; Hirsh, T.; Heckmaier, E.; Marley, S. T.; Morgan, G.; Orford, R.; Sharma, K. S.

    2017-01-01

    The weak interaction is framed in the Standard Model with a pure vector-axial vector structure. A high-precision measurement of the β - ν correlation coefficient (aβν) could reveal contributions from tensor or scalar currents and give insight into new physics. We utilize stopped 8Li in the Beta decay Paul Trap (BPT) at Argonne National Lab to measure aβν. The BPT is surrounded on 4 sides with double-sided silicon strip detectors backed by plastic scintillator detectors, which allow the kinematics of the 8Li decay products to be over-constrained. A previous measurement done by our collaboration resulted in the first improvement in over 50 years to the tensor limit of aβν in a nuclear setting and was recently published in PRL. We have since upgraded our system and obtained over ten times our previous statistics. Our goal is to achieve a limit of aβν with an uncertainty of 0.001. Analysis is ongoing. We acknowledge NSERC, Canada, App. No. 216974, the U.S. DOE Contract No. DE-AC02-06CH11357 [ANL] and DE-AC52-07NA27344 [LLNL], NSF Grant No. 1144082 and the ANL ATLAS facility

  17. Elastic Scattering of ^6He and ^8Li on ^58Ni---

    NASA Astrophysics Data System (ADS)

    Kolata, Jj; Guimares, V.; Peterson, D.; Santi, P.; von Schwarzenberg, J.; Staples, Cj; Deyoung, P.; Jolivette, Pl; Peaslee, G.; Hinnefeld, Jd; Becchetti, Fd; Lee, My; Roberts, Da

    1997-10-01

    Elastic scattering of ^6He and ^8Li on ^58Ni has been measured at beam energies of approximately 30 MeV, or 4 MeV per nucleon. This was the `commissioning' experiment for the recently upgraded radioactive nuclear beam (RNB) facility at the University of Notre Dame. A total energy resolution of about 300 keV was achieved, and the beam purity exceeded 75%. Remarkably, no ^7Li primary beam could be detected in the secondary beam in either case, implying beam rejection factors exceeding 1x10^12. The experiment was designed to respond to the challenge to study elastic and inelastic scattering of RNB's at angles well beyond `grazing'. In the case of ^8Li, previous inelastic data at energies below(J.A. Brown,et al.) , Phys. Rev. Lett.66 , 2452 (1991). and above(R.J. Smith,et al.), Phys. Rev.C43 , 2346 (1991). the Coulomb barrier indicated an anomalously strong transition to the excited state of the projectile. Data that relate to these two issues will be presented. This work was supported by the US National Science Foundation.

  18. Compound Nucleus Contributions to the Optical Potential

    SciTech Connect

    Thompson, I. J.; Dietrich, F. S.; Escher, J. E.; Dupuis, M.

    2008-04-17

    An ab-initio calculation of the optical potential for neutron-nucleus scattering has been performed by explicitly coupling the elastic channel to all the particle-hole (p-h) excitation states in the target. These p-h states may be regarded as doorway states through which the flux flows to more complicated configurations, and (in the end) to long-lived compound nucleus resonances. The random-phase approximation (RPA) provides the linear combinations of p-h states that include the residual interactions within the target, and we show preliminary results for elastic flux loss using both p-h and RPA descriptions of target excitations.

  19. The MTV experiment: a test of time reversal symmetry using polarized 8Li

    NASA Astrophysics Data System (ADS)

    Murata, J.; Baba, H.; Behr, J. A.; Hirayama, Y.; Iguri, T.; Ikeda, M.; Kato, T.; Kawamura, H.; Kishi, R.; Levy, C. D. P.; Nakaya, Y.; Ninomiya, K.; Ogawa, N.; Onishi, J.; Openshaw, R.; Pearson, M.; Seitaibashi, E.; Tanaka, S.; Tanuma, R.; Totsuka, Y.; Toyoda, T.

    2014-01-01

    The MTV ( Mott Polarimetry for T- Violation Experiment) experiment at TRIUMF-ISAC ( Isotope Separator and ACcelerator), which aims to achieve the highest precision test of time reversal symmetry in polarized nuclear beta decay by measuring a triple correlation ( R-correlation), is motivated by the search for a new physics beyond the Standard Model. In this experiment, the existence of non-zero transverse electron polarization is examined utilizing the analyzing power of Mott scattering from a thin metal foil. Backward scattering electron tracks are measured using a multi-wire drift chamber for the first time. The MTV experiment was commissioned at ISAC in 2009 using an 80 % polarized 8Li beam at 107 pps, resulting in 0.1 % statistical precision on the R-parameter in the first physics run performed in 2010. Next generation cylindrical drift chamber (CDC) is now being installed for the future run.

  20. The 7Li(d, p)8Li reaction in inverse kinematics at 5.44 MeV/u

    NASA Astrophysics Data System (ADS)

    Pakou, A.; Keeley, N.; Cappuzzello, F.; Acosta, L.; Agodi, C.; Aslanoglou, X.; Calabrese, S.; Carbone, D.; Cavallaro, M.; Foti, A.; Marquínez-Durán, G.; Martel, I.; Mazzocco, M.; Parascandolo, C.; Pierroutsakou, D.; Rusek, K.; Sgouros, O.; Soukeras, V.; Strano, E.; Zagatto, V. A. B.

    2017-08-01

    New data are presented for the 7Li(d, p)8Li stripping reaction which, together with previously reported elastic scattering data taken in the same experiment, provide a coherent set. These data, plus existing measurements of the elastic scattering and stripping at 6MeV/u were analysed within the same coupled reaction channels scheme. Good descriptions of the stripping data to the 0.0MeV 2^+ and 0.98MeV 1^+ states of 8Li were obtained using a set of < ^8Li| ^7Li + n〉 overlaps taken from the literature, provided that the elastic scattering was also well described. Multi-step reaction paths made significant contributions to the description of the larger angle data. The asymptotic normalisation coefficients are compared with previous determinations.

  1. Nanoscale "Dark State" Optical Potentials for Cold Atoms.

    PubMed

    Łącki, M; Baranov, M A; Pichler, H; Zoller, P

    2016-12-02

    We discuss the generation of subwavelength optical barriers on the scale of tens of nanometers, as conservative optical potentials for cold atoms. These arise from nonadiabatic corrections to Born-Oppenheimer potentials from dressed "dark states" in atomic Λ configurations. We illustrate the concepts with a double layer potential for atoms obtained from inserting an optical subwavelength barrier into a well generated by an off-resonant optical lattice, and discuss bound states of pairs of atoms interacting via magnetic dipolar interactions. The subwavelength optical barriers represent an optical "Kronig-Penney" potential. We present a detailed study of the band structure in optical Kronig-Penney potentials, including decoherence from spontaneous emission and atom loss to open "bright" channels.

  2. Structure of the real part of the nucleon optical potential

    SciTech Connect

    Kadmensky, S.G.; Lyuboshitz, V.V.; Shaikina, A.A.

    1995-09-01

    The components of the nucleon optical potential V(l, E) in the {sup 208}Pb and {sup 40}Ca nuclei are calculated on the basis of the generalized Hartree-Fock potential and using typical sets of vacuum NN forces. The parameters of the isoscalar component of V(1, E) are found to agree well with those of phenomenological optical potentials and of the optical potentials in the Skyrme model. The isovector component of V(1, E) strongly depends on energy, and its value at E = 0 is considerably less than the corresponding values of the phenomenological and Skyrme optical potentials. This points to the necessity of additional tests of the underlying pair NN potentials. The radial distribution of V(1, E) is more complicated than the radial dependence of phenomenological optical potentials. 6 refs., 5 figs.

  3. Fiber Optics (Optical Waveguides) Technology - Potential Application in the DCS.

    DTIC Science & Technology

    1981-02-01

    between areas ti,,t have high voltage differences , a safety hazard to the personnel can also occur. The use of fiber optics cormunicL, 4ans cable can...entered in Block 20, If different from Report) 18. SUPPLEMENTARY NOTES Review relevance 5 years from submission date. 19 KEY WORDS (Cnntinue oil reverse...placed much farther apart. It provides electrical isolation, even between high voltage areas, because the transmission medium is an electrical insulator

  4. Low-energy K- optical potentials: deep or shallow?

    NASA Astrophysics Data System (ADS)

    Cieplý, A.; Friedman, E.; Gal, A.; Mareš, J.

    2001-12-01

    The K- optical potential in the nuclear medium is evaluated self consistently from a free-space K-Nt matrix constructed within a coupled-channel chiral approach. The fit of model parameters gives a good description of the low-energy data plus the available K- atomic data. The resulting optical potential is relatively `shallow' in contradiction to the potentials obtained from phenomenological analysis. The calculated (Kstop-,π) hypernuclear production rates are very sensitive to the details of kaonic bound state wave function. The (Kstop-,π) reaction could thus serve as a suitable tool to distinguish between shallow and deep K- optical potentials.

  5. Determination of the nature of fluctuations using 8Li and 9Liβ -NMR and spin-lattice relaxation

    NASA Astrophysics Data System (ADS)

    Chatzichristos, A.; McFadden, R. M. L.; Karner, V. L.; Cortie, D. L.; Levy, C. D. P.; MacFarlane, W. A.; Morris, G. D.; Pearson, M. R.; Salman, Z.; Kiefl, R. F.

    2017-07-01

    We report a comparison of the 1 /T1 spin-lattice relaxation rates for 9Li and 8Li in Pt and SrTiO3, in order to differentiate between magnetic and electric quadrupolar relaxation mechanisms. In Pt, the ratio of the 1 /T1 spin relaxation rates RPt was found to be 6.82(29), which is close to but less than the theoretical limit of ˜7.68 for pure magnetic relaxation. In SrTiO3 this ratio was found to be 2.7(3), which is close to but larger than the theoretical limit of ˜2.14 expected for pure electric quadrupolar relaxation. These results bring insight into the nature of the fluctuations in the local environment of implanted 8Li observed by β -NMR.

  6. In situ lithium diffusion measurement in solid ionic conductors using short-lived radiotracer beam of 8Li

    NASA Astrophysics Data System (ADS)

    Ishiyama, H.; Jeong, S. C.; Watanabe, Y. X.; Hirayama, Y.; Imai, N.; Miyatake, H.; Oyaizu, M.; Osa, A.; Otokawa, Y.; Matsuda, M.; Nishio, K.; Makii, H.; Sato, T. K.; Kuwata, N.; Kawamura, J.; Nakao, A.; Ueno, H.; Kim, Y. H.; Kimura, S.; Mukai, M.

    2015-07-01

    We developed an in situ radiotracer method for diffusion studies in solids using short-lived α-emitting 8Li tracer. In the method, while implanting a pulsed 8Li beam into a solid material of interest, the α particles emitted into the implantation side of the sample surface were detected as a function of time. By changing the implantation depth and the detection angle against the sample surface according to lithium diffusivity (deep implantation and large angle with a large solid angle, or shallow implantation and small angle with a narrow solid angle), the method can be sensitive to a wide range of diffusion length ranging from micrometer scale to nanometer scale per second. The feasibility of the method was demonstrated by measuring the lithium diffusion coefficients to the order of 10-12 cm2/s in lithium ionic conductors.

  7. An electrochromic window based on Li sub x WO sub 3 /(PEO) sub 8 LiCIO sub 4 /NiO

    SciTech Connect

    Passerini, S.; Scosati, B. ); Gorenstein, A. ); Anderson, A.M; Granqvist, C.G. )

    1989-11-01

    Electrochromic materials are characterized by reversible but persistent changes of the optical properties when subjected to suitable electrochemical reactions. Electrochromism can be utilized in windows, most conveniently by exploiting all-solid-state multilayer coating backed by glass. The multilayer coating should comprise the following sequence of layers: a transparent and electrically conducting base layer, an electrochromic layer, and electrolyte, a conterelectrode, and a transparent conducting top layer. For window applications, the electrolyte should be transparent, and the conterelectrode must be either optically passive (colorless irrespective of its ionic content) or electrochromic in a sense that is complementary to the electrochromism of the electrochromic layer. The latter condition implies that if the electrochromic layer is cathodic (anodic), the counterelectrode must be anodic (cathodic). This paper reports preliminary data taken on samples with electrochromic layers based on tungsten oxide, WO{sub 3}, and nickel oxide, NiO, and an intermediate solid electrolyte of poly(ethylene oxide) doped with lithium perchlorate, (PEO){sub 8}LiClO{sub 4}, where 8 signifies the number of oxygen heteroatoms per lithium ion.

  8. Trapping of a microsphere pendulum resonator in an optical potential

    SciTech Connect

    Ward, J. M.; Wu, Y.; Nic Chormaic, S.; Minogin, V. G.

    2009-05-15

    We propose a method to spatially confine or corral the movements of a micropendulum via the optical forces produced by two simultaneously excited optical modes of a photonic molecule comprising two microspherical cavities. We discuss how the cavity-enhanced optical force generated in the photonic molecule can create an optomechanical potential of about 10 eV deep and 30 pm wide, which can be used to trap the pendulum at any given equilibrium position by a simple choice of laser frequencies. This result presents opportunities for very precise all-optical self-alignment of microsystems.

  9. Nonlinear Optical Image Subtraction For Potential Industrial Applications

    NASA Astrophysics Data System (ADS)

    Chiou, Arthur E.; Yeh, Pochi; Khoshnevisan, Monte

    1988-05-01

    Recent advances in optical phase conjugation and energy coupling at optical powers as low as a few milliwatts have added a new dimension to optical image processing. Conventional image processing techniques based on convolution/correlation, matched filtering, and holographic interferometry can now be achieved with much simpler components and usually at much higher efficiency by incorporating these new features. Some of the application concepts that had been impracticable can now be realized. The basic principle and potential industrial applications of real-time image subtraction using dynamic holograms are reviewed. Optical implementations and experimental results on image subtraction, novelty filtering, and defect detection are discussed.

  10. A comparison of optical clearing potential of disaccharide with monosaccharide

    NASA Astrophysics Data System (ADS)

    Feng, Wei; Ma, Ning; Zhu, Dan

    2014-09-01

    Molecular dynamics (MD) simulation provides a quantitative method for screening efficient optical clearing agents. Some excellent optical clearing agents were obtained through the MD simulation of alcohols with hydroxyl groups. Among of the agents, fructose, one of polyols has the better efficacy which is one of monoaccharides. In comparison, disaccharides received little attention. In this study, sucrose and maltose were screened from common disaccharides for comparing with fructose. Actually, each agent has different saturation concentration. Here, the combination of molecular dynamic simulation and in vitro experiment was employed in this study. Firstly, the hydrogen bonds were used to predict the optical clearing potential of sucrose, maltose and fructose by using molecular dynamic simulation, respectively. The simulated results indicated that the optical clearing potential in a descending order as: sucrose, maltose and fructose. The reduced scattering coefficient of in vitro rat skin samples was used to evaluate the skin optical clearing potential based on measurements of reflectance and transmittance using a commercial spectrophotometer with an integrating sphere. Both the experimental and simulated results show that for the same concentration, disaccharides have better optical clearing potential than fructose. However, maltose has too low saturation concentration to produce similar optical clearing efficacy as the other two. By contrast, sucrose is the best one even though it has lower saturation concentrations than fructose.

  11. Optical probes of membrane potential in heart muscle.

    PubMed Central

    Morad, M; Salama, G

    1979-01-01

    1. The fluorescent dye Merocyanine-540 and the two weakly fluoresecnet dyes Merocyanine-rhodanine and Merocyanine-oxazolone are shown to respond as optical probes of membrane potential in heart muscle. 2. In frog hearts stained with Merocyanine-540, the absorption at 540 nm decreases by 0.1-1.0% and increase at 570 nm excitation wave-length, the fluorescence increases by 1-2%. The time course of all three optical measurements follows the kinetics of the action potential. 3. Merocyanine-rhodanine exhibits potential-dependent optical responses through a 0.5% decrease in absorption at 750 nm, and Merocyanine-oxazolone has a 1.0% decrease in absorption at 720 nm. Their optical responses have a signal-to-noise ratio of 100/1 and 500/1, respectively. 4. The action spectrum of Merocyanine-rhodanine is triphasic in frog heart with an increase in transmittance from 780 to 700, a decrease from 700 to 600, and increase from 600 to 450 nm. Merocyanine-oxazolone shows only increases in transmittance during membrane depolarization. 5. The optical responses of these probes are linear with respect to changes in membrane potential. 6. Pharmacological agents or ionic interventions do not alter the membrane potential sensitivity of Merocyanine-540. 7. Rapid spectrophotometric measurements at various phases of the action potential indicate that the potential dependent optical signals of Merocyanine-540 are produced by changes in amplitude of fluorescence and absorption bands. The lack of wave-length displacement as a function of membrane potential, i.e. electrochromism, is not the mechanism governing the voltage sensitivity of Merocyanine-540. 8. The data suggest that these Merocyanine dyes bind to the plasma membrane and serve as linear optical probes of membrane potential in heart muscle. PMID:314976

  12. Important influence of single neutron stripping coupling on near-barrier 8Li + 90Zr quasi-elastic scattering

    NASA Astrophysics Data System (ADS)

    Pakou, A.; Keeley, N.; Pierroutsakou, D.; Mazzocco, M.; Acosta, L.; Aslanoglou, X.; Boiano, A.; Boiano, C.; Carbone, D.; Cavallaro, M.; Grebosz, J.; La Commara, M.; Manea, C.; Marquinez-Duran, G.; Martel, I.; Parascandolo, C.; Rusek, K.; Sánchez-Benítez, A. M.; Sgouros, O.; Signorini, C.; Soramel, F.; Soukeras, V.; Stiliaris, E.; Strano, E.; Torresi, D.; Trzcińska, A.; Watanabe, Y. X.; Yamaguchi, H.

    2015-07-01

    Quasi-elastic scattering data were obtained for the radioactive nucleus 8Li on a 90Zr target at the near-barrier energy of 18.5MeV over the angular range to 80°. They were analyzed within the coupled channels and coupled reaction channels frameworks pointing to a strong coupling effect for single neutron stripping, in contrast to 6, 7 Li + 90 Zr elastic scattering at similar energies, a non-trivial result linked to detailed differences in the structure of these Li isotopes.

  13. Potential for integrated optical circuits in advanced aircraft with fiber optic control and monitoring systems

    NASA Technical Reports Server (NTRS)

    Baumbick, Robert

    1991-01-01

    The current Fiber Optic Control System Integration (FOCSI) program is reviewed and the potential role of IOCs in FOCSI applications is described. The program is intended for building, environmentally testing, and demonstrating operation in piggyback flight tests (no active control with optical sensors) of a representative sensor system for propulsion and flight control. The optical sensor systems are to be designed to fit alongside the bill-of-materials sensors for comparison. The sensors are to be connected to electrooptic architecture cards which will contain the optical sources and detectors to recover and process the modulated optical signals. The FOCSI program is to collect data on the behavior of passive optical sensor systems in a flight environment and provide valuable information on installation amd maintenance problems for this technology, as well as component survivability (light sources, connectors, optical fibers, etc.).

  14. Potential for integrated optical circuits in advanced aircraft with fiber optic control and monitoring systems

    NASA Technical Reports Server (NTRS)

    Baumbick, Robert

    1991-01-01

    The current Fiber Optic Control System Integration (FOCSI) program is reviewed and the potential role of IOCs in FOCSI applications is described. The program is intended for building, environmentally testing, and demonstrating operation in piggyback flight tests (no active control with optical sensors) of a representative sensor system for propulsion and flight control. The optical sensor systems are to be designed to fit alongside the bill-of-materials sensors for comparison. The sensors are to be connected to electrooptic architecture cards which will contain the optical sources and detectors to recover and process the modulated optical signals. The FOCSI program is to collect data on the behavior of passive optical sensor systems in a flight environment and provide valuable information on installation amd maintenance problems for this technology, as well as component survivability (light sources, connectors, optical fibers, etc.).

  15. Global optical model potential for A=3 projectiles

    NASA Astrophysics Data System (ADS)

    Pang, D. Y.; Roussel-Chomaz, P.; Savajols, H.; Varner, R. L.; Wolski, R.

    2009-02-01

    A global optical model potential (GDP08) for He3 projectiles has been obtained by simultaneously fitting the elastic scattering data of He3 from targets of 40⩽AT⩽209 at incident energies of 30⩽Einc⩽217 MeV. Uncertainties and correlation coefficients between the global potential parameters were obtained by using the bootstrap statistical method. GDP08 was found to satisfactorily account for the elastic scattering of H3 as well, which makes it a global optical potential for the A=3 nuclei. Optical model calculations using the GDP08 global potential are compared with the experimental angular distributions of differential cross sections for He3-nucleus and H3-nucleus scattering from different targets of 6⩽AT⩽232 at incident energies of 4⩽Einc⩽450 MeV. The optical potential for the doubly-magic nucleus Ca40, the low-energy correction to the real potential for nuclei with 58≲AT≲120 at Einc<30 MeV, the comparison with double-folding model calculations and the CH89 potential, and the spin-orbit potential parameters are discussed.

  16. α-Cluster Optical Potential Model of 40Ca

    NASA Astrophysics Data System (ADS)

    Mahmoud, Zakaria M. M.; Behairy, Kassem O.

    2017-04-01

    Elastic scattering of α + 40Ca is analyzed in the framework of the optical model. We adopted an independent α-cluster model to generate the α-cluster and matter density of 40Ca. We proposed a parametrized form for the α-cluster density and fixed its parameters according to the available experimental data about the α-particle and 40Ca nuclei. The obtained α-cluster density of 40Ca is used to generate the real part of the optical potential. The single folding procedure is used to generate this real optical potential with two different effective α-α interactions. The real calculated potential supplied with an imaginary Woods-Saxon squared potential is used to analyze 20 sets of experimental data in the energy range between 18 and 166 MeV. We found that our model is successful in reproducing the data for energies above 40 MeV and still doubtful for lower energies.

  17. α-Cluster Optical Potential Model of 40Ca

    NASA Astrophysics Data System (ADS)

    Mahmoud, Zakaria M. M.; Behairy, Kassem O.

    2017-01-01

    Elastic scattering of α + 40Ca is analyzed in the framework of the optical model. We adopted an independent α-cluster model to generate the α-cluster and matter density of 40Ca. We proposed a parametrized form for the α-cluster density and fixed its parameters according to the available experimental data about the α-particle and 40Ca nuclei. The obtained α-cluster density of 40Ca is used to generate the real part of the optical potential. The single folding procedure is used to generate this real optical potential with two different effective α-α interactions. The real calculated potential supplied with an imaginary Woods-Saxon squared potential is used to analyze 20 sets of experimental data in the energy range between 18 and 166 MeV. We found that our model is successful in reproducing the data for energies above 40 MeV and still doubtful for lower energies.

  18. Microscopic optical potentials for He4 scattering

    NASA Astrophysics Data System (ADS)

    Egashira, Kei; Minomo, Kosho; Toyokawa, Masakazu; Matsumoto, Takuma; Yahiro, Masanobu

    2014-06-01

    We present a reliable double-folding (DF) model for He4-nucleus scattering, using the Melbourne g-matrix nucleon-nucleon interaction that explains nucleon-nucleus scattering with no adjustable parameter. In the DF model, only the target density is taken as the local density in the Melbourne g matrix. For He4 elastic scattering from Ni58 and Pb208 targets in a wide range of incident energies from 20 to 200 MeV/nucleon, the DF model with the target-density approximation (TDA) yields much better agreement with the experimental data than the usual DF model with the frozen-density approximation in which the sum of projectile and target densities is taken as the local density. We also discuss the relation between the DF model with the TDA and the conventional folding model in which the nucleon-nucleus potential is folded with the He4 density.

  19. Guiding of atoms in helical optical potential structures

    NASA Astrophysics Data System (ADS)

    Rsheed, Anwar Al; Lyras, Andreas; Lembessis, Vassilis E.; Aldossary, Omar M.

    2016-06-01

    The classical dynamics of a cold atom trapped inside a static helical optical potential is investigated based on the Lagrangian formalism, which takes into account both the optical light field and the gravitational field. The resulting equations of motion are solved numerically and analytically. The topology of the helical optical potential, which drives the trapped cold atom, is responsible for two different types of oscillations, namely: the local oscillations, whereby the atomic motion is confined in a region smaller than the light field wavelength (z\\lt λ ) and the global oscillations, when the atomic motion is extended to larger regions comparable to the beam Rayleigh range (z\\lt {z}{{R}}). Local oscillations guide the atom along the helical structure of the optical potential. The global oscillations, which constitute the main topic of our paper, define the atomic motion along the z-axis as an oscillation between two turning points. For typical values of the beam waist {w}{{o}} the turning points are symmetrical around the origin. For large values of the beam waist {w}{{o}}, the global oscillations become asymmetric because the optical dipole potential weakens and the gravitational potential contributes to the determination of the turning points. For sufficiently large values of the beam waist {w}{{o}}, there are no global oscillations and only one upper turning point defines the atom’s global motion.

  20. Optical mapping of optogenetically shaped cardiac action potentials

    PubMed Central

    Park, Sarah A.; Lee, Shin-Rong; Tung, Leslie; Yue, David T.

    2014-01-01

    Light-mediated silencing and stimulation of cardiac excitability, an important complement to electrical stimulation, promises important discoveries and therapies. To date, cardiac optogenetics has been studied with patch-clamp, multielectrode arrays, video microscopy, and an all-optical system measuring calcium transients. The future lies in achieving simultaneous optical acquisition of excitability signals and optogenetic control, both with high spatio-temporal resolution. Here, we make progress by combining optical mapping of action potentials with concurrent activation of channelrhodopsin-2 (ChR2) or halorhodopsin (eNpHR3.0), via an all-optical system applied to monolayers of neonatal rat ventricular myocytes (NRVM). Additionally, we explore the capability of ChR2 and eNpHR3.0 to shape action-potential waveforms, potentially aiding the study of short/long QT syndromes that result from abnormal changes in action potential duration (APD). These results show the promise of an all-optical system to acquire action potentials with precise temporal optogenetics control, achieving a long-sought flexibility beyond the means of conventional electrical stimulation. PMID:25135113

  1. Observation of PT-Symmetry Breaking in Complex Optical Potentials

    SciTech Connect

    Guo, A.; Salamo, G. J.; Duchesne, D.; Morandotti, R.; Volatier-Ravat, M.; Aimez, V.; Siviloglou, G. A.; Christodoulides, D. N.

    2009-08-28

    In 1998, Bender and Boettcher found that a wide class of Hamiltonians, even though non-Hermitian, can still exhibit entirely real spectra provided that they obey parity-time requirements or PT symmetry. Here we demonstrate experimentally passive PT-symmetry breaking within the realm of optics. This phase transition leads to a loss induced optical transparency in specially designed pseudo-Hermitian guiding potentials.

  2. Study of chirally motivated low-energy K - optical potentials

    NASA Astrophysics Data System (ADS)

    Cieplý, A.; Friedman, E.; Gal, A.; Mareš, J.

    2001-12-01

    The K - optical potential in the nuclear medium is evaluated self consistently from a free-space K -N t matrix constructed within a coupled-channel chiral approach to the low-energy K¯N data. The chiral-model parameters are fitted to a select subset of the low-energy data plus the K - atomic data throughout the periodic table. The resulting attractive K - optical potentials are relatively 'shallow', with central depth of the real part about 55 MeV, for a fairly reasonable reproduction of the atomic data with χ2/ N≈2.2. Relatively 'deep' attractive potentials of depth about 180 MeV, which result in other phenomenological approaches with χ2/ N≈1.5, are ruled out within chirally motivated models. Different physical data input is required to distinguish between shallow and deep K - optical potentials. The (K -stop, π) reaction could provide such a test, with exclusive rates differing by over a factor of three for the two classes of potentials. Finally, forward (K -,p) differential cross sections for the production of relatively narrow deeply bound K -nuclear states are evaluated for deep K - optical potentials, yielding values considerably lower than those estimated before.

  3. Separable representation of multichannel nucleon-nucleus optical potentials

    NASA Astrophysics Data System (ADS)

    Hlophe, L.; Elster, Ch.

    2017-05-01

    Background: One important ingredient for many applications of nuclear physics to astrophysics, nuclear energy, and stockpile stewardship is cross sections for reactions of neutrons with rare isotopes. Since direct measurements are often not feasible, indirect methods, e.g., (d ,p ) reactions, should be used. Those (d ,p ) reactions may be viewed as three-body reactions and described with Faddeev techniques. Purpose: Faddeev equations in momentum space have a long tradition of utilizing separable interactions in order to arrive at sets of coupled integral equations in one variable. Optical potentials representing the effective interactions in the neutron (proton) nucleus subsystem are usually non-Hermitian as well as energy dependent. Including excitations of the nucleus in the calculation requires a multichannel optical potential. The purpose of this paper is to introduce a separable, energy-dependent multichannel representation of complex, energy-dependent optical potentials that contain excitations of the nucleus and that fulfill reciprocity exactly. Methods: Momentum space Lippmann-Schwinger integral equations are solved with standard techniques to obtain the form factors for the separable representation. Results: Starting from energy-dependent multichannel optical potentials for neutron and proton scattering from 12C, separable representations based on a generalization of the Ernst-Shakin-Thaler (EST) scheme are constructed which fulfill reciprocity exactly. Applications to n +12C and p +12C scattering are investigated for energies from 0 to 50 MeV. Conclusions: We find that the energy-dependent separable representation of complex, energy-dependent phenomenological multichannel optical potentials describes scattering data with the same quality as the original potential.

  4. Hindrance of complete fusion in the {sup 8}Li+{sup 208}Pb system at above-barrier energies

    SciTech Connect

    Aguilera, E. F.; Martinez-Quiroz, E.; Rosales, P.; Kolata, J. J.; DeYoung, P. A.; Peaslee, G. F.; Mears, P.; Guess, C.; Becchetti, F. D.; Lupton, J. H.; Chen, Yu

    2009-10-15

    The {sup 211,212}At yields resulting from the interaction of the radioactive projectile {sup 8}Li with a {sup 208}Pb target have been measured at energies between 3 and 8.5 MeV above the Coulomb barrier. They are signatures for fusion of the whole charge but not necessarily the whole mass of the projectile, so they are included in a corresponding operational definition of complete fusion. Within this definition, a fusion suppression factor of 0.70{+-}0.02 (stat.) {+-}0.04 (syst.) is deduced from a comparison to a one-dimensional barrier-penetration-model calculation using parameters extrapolated from values for {sup 6,7}Li+{sup 209}Bi and {sup 9}Be+{sup 208}Pb taken from the literature. Possible incomplete fusion processes are discussed and the results are fitted with a phenomenological model assuming breakup prior to fusion followed by capture of a {sup 7}Li fragment.

  5. Optical elements formed by compressed gases: Analysis and potential applications

    NASA Technical Reports Server (NTRS)

    Howes, W. L.

    1986-01-01

    Spherical, cylindrical, and conical shock waves are optically analogous to gas lenses. The geometrical optics of these shock configurations are analyzed as they pertain to flow visualization instruments, particularly the rainbow schlieren apparatus and single-pass interferometers. It is proposed that a lens or mirror formed by gas compressed between plastic sheets has potential as a fluid visualization test object; as the objective mirror in a very large space-based telescope, communication antenna, or energy collector; as the objective mirror in inexpensive commercial telescopes; and as a component in fluid visualization apparatuses.

  6. The real optical- and shell-model potentials

    SciTech Connect

    Lawson, R.D.; Chiba, S.; Guenther, P.T.; Smith, A.B.

    1990-01-01

    From fits to neutron scattering data over a wide range of nuclei it is shown that r{sub v}, the reduced radius of the real optical-model potential, decreases with increasing A. The value of the isovector part of the real potential is discussed and a simple argument is given for its magnitude. The dispersion relationship and the method of moments are used to extrapolate the scattering potential to the bound-state regime. The possibility of deducing the spin-orbit strength from the observed single-particle binding energies is discussed. 13 refs., 1 fig., 2 tabs.

  7. Separable representation of energy-dependent optical potentials

    NASA Astrophysics Data System (ADS)

    Hlophe, L.; Elster, Ch.

    2016-03-01

    Background: One important ingredient for many applications of nuclear physics to astrophysics, nuclear energy, and stockpile stewardship are cross sections for reactions of neutrons with rare isotopes. Since direct measurements are often not feasible, indirect methods, e.g., (d ,p ) reactions, should be used. Those (d ,p ) reactions may be viewed as three-body reactions and described with Faddeev techniques. Purpose: Faddeev equations in momentum space have a long tradition of utilizing separable interactions in order to arrive at sets of coupled integral equations in one variable. Optical potentials representing the effective interactions in the neutron (proton) nucleus subsystem are usually non-Hermitian as well as energy dependent. Potential matrix elements as well as transition matrix elements calculated with them must fulfill the reciprocity theorem. The purpose of this paper is to introduce a separable, energy-dependent representation of complex, energy-dependent optical potentials that fulfill reciprocity exactly. Methods: Momentum space Lippmann-Schwinger integral equations are solved with standard techniques to obtain the form factors for the separable representation. Results: Starting from a separable, energy-independent representation of global optical potentials based on a generalization of the Ernst-Shakin-Thaler (EST) scheme, a further generalization is needed to take into account the energy dependence. Applications to n +48Ca ,n +208Pb , and p +208Pb are investigated for energies from 0 to 50 MeV with special emphasis on fulfilling reciprocity. Conclusions: We find that the energy-dependent separable representation of complex, energy-dependent phenomenological optical potentials fulfills reciprocity exactly. In addition, taking into account the explicit energy dependence slightly improves the description of the S matrix elements.

  8. Super-linear optical modulator technologies for optical broadband access network: development and potential

    NASA Astrophysics Data System (ADS)

    Dingel, Benjamin B.; Madabhushi, Rangaraj; Madamopoulos, Nicholas

    2005-10-01

    Linearized optical intensity modulator is recognized as one of the building blocks in any analog fiber-optics links systems such as subcarrier multiplexing (SCM) systems, ultra-dense CATV, Radio-over-Fiber (RoF) communications, and other platform access systems. For more than 30 years, the quest for highly linearized optical modulator with SFDR > 130 dB-Hz 2/3 represents a major, on-going technology goal. This invited paper has three-fold objective namely: (1) provide comprehensive overview of the numerous existing linearized optical intensity modulators, (2) introduce a classification of these linearized modulators, and (3) present recent development of new, super-linear (SFDR = 130-140 dB-Hz 2/3) modulator which the authors pioneered. Other features of this new modulator are simple setup, high tolerance and low-cost. Performance results are presented via numerical simulation, its potential applications and limitations are also discussed.

  9. Optical Fiber System For The Optical Monitoring Of Membrane Potentials Of Excitable Tissues.

    NASA Astrophysics Data System (ADS)

    Nassif, G.; Fillette, F.; Kado, R. T.

    1988-06-01

    Spectrometry of potential-sensitive dyes permits now the monitoring of membrane potential (MP) variations on excitable tissues. It is also possible to monitor qualitatively the electromechanical activity (EMA) on contractile tissues using this same method. We improved two new optical fiber systems for measuring fluorescence. System 1 used two 200 um optical fibers permitting fluorescence excitation of the potential sensitive dye (PSD) (1st Fiber) and the measurement of its fluorescence (2nd Fiber). System 2 used two 200 um optical fibers for a differencial measurement of excitation reflexion and fluorescence through two different optical filters. The two fibers are assembled in a tube to constitute the "Optrode". In System 1, a single photodiode placed behind a 665 nm high pass optical filter (HPOF) is preamplified by a LH-0022 op. amplifier. In system 2, two photodiodes are placed respectively behind a 645 nm and a 665 nm HPOFs and differencialy preampli-fied by a AD-521 instrumentation amplifier. Analogic signals are lowpass filtered with a LT-1062 digital filter. PSDs WW781 and RH 237 were used respectively on myocardial and nervous tissues. Fluorescence excitation of PSD WW 781 was performed with a 5 mWatts Helium-Neon LASER (He-Ne) beam focused into the first opti-cal fiber of System 1 or illuminating directly the stained tissue. Fluorescence excitation of PSD RH 237 was performed with a 100 Watts filament lamp through a 400-500 nm blue bandpass filter (BBPF). These two systems are now used to study MP variations on myocardial and nervous tissues. We are now able to study the effects of different drugs on the EMA of heart muscle. This technique is usable "in Vitro" and "in Vivo". This optical fiber method easy to improve for a low cost permits now to perform studies on excitable tissues in a non traumatic way with foreseeable applications to pharmacological investigations on experimental models.

  10. Molecular effective coverage surface area of optical clearing agents for predicting optical clearing potential

    NASA Astrophysics Data System (ADS)

    Feng, Wei; Ma, Ning; Zhu, Dan

    2015-03-01

    The improvement of methods for optical clearing agent prediction exerts an important impact on tissue optical clearing technique. The molecular dynamic simulation is one of the most convincing and simplest approaches to predict the optical clearing potential of agents by analyzing the hydrogen bonds, hydrogen bridges and hydrogen bridges type forming between agents and collagen. However, the above analysis methods still suffer from some problem such as analysis of cyclic molecule by reason of molecular conformation. In this study, a molecular effective coverage surface area based on the molecular dynamic simulation was proposed to predict the potential of optical clearing agents. Several typical cyclic molecules, fructose, glucose and chain molecules, sorbitol, xylitol were analyzed by calculating their molecular effective coverage surface area, hydrogen bonds, hydrogen bridges and hydrogen bridges type, respectively. In order to verify this analysis methods, in vitro skin samples optical clearing efficacy were measured after 25 min immersing in the solutions, fructose, glucose, sorbitol and xylitol at concentration of 3.5 M using 1951 USAF resolution test target. The experimental results show accordance with prediction of molecular effective coverage surface area. Further to compare molecular effective coverage surface area with other parameters, it can show that molecular effective coverage surface area has a better performance in predicting OCP of agents.

  11. Potentials and challenges of using orbital angular momentum communications in optical interconnects.

    PubMed

    Yu, Siyuan

    2015-02-09

    Ultra-short- and short-reach optical interconnects are the new high growth applications for optical communications. High capacity density, high spectral efficiency, low cost, low power consumption, and fast configurability are some of the key requirements for potential optical transmission technology candidates. Based on recent progress in orbital angular momentum multiplexed optical transmission and optical device technologies, this paper discusses the potentials and challenges of using orbital angular momentum multiplexing in optical interconnect applications scenarios to meet above requirements.

  12. Electrical/optical dual-function redox potential transistor

    PubMed Central

    Li, Shunpu; Wang, Wensi; Xu, Ju; Chu, Daping; Shen, Z. John; Roy, Saibal

    2013-01-01

    We demonstrate a new type of transistors, the electrical/optical “dual-function redox-potential transistors”, which is solution processable and environmentally stable. This device consists of vertically staked electrodes that act as gate, emitter and collector. It can perform as a normal transistor, whilst one electrode which is sensitised by dye enables to generate photocurrent when illuminated. Solution processable oxide-nanoparticles were used to form various functional layers, which allow an electrolyte to penetrate through and, consequently, the current between emitter and collector can be controlled by the gate potential modulated distribution of ions. The result here shows that the device performs with high ON-current under low driving voltage (<1 V), while the transistor performance can readily be controlled by photo-illumination. Such device with combined optical and electrical functionalities allows single device to perform the tasks that are usually done by a circuit/system with multiple optical and electrical components, and it is promising for various applications. PMID:24310311

  13. Transient visually evoked potentials to sinusoidal gratings in optic neuritis.

    PubMed Central

    Plant, G T

    1983-01-01

    Transient visually evoked potentials (VEPs) to sinusoidal gratings over a range of spatial frequencies have been recorded in cases of optic neuritis. The use of the response to pattern onset in addition to the response to pattern reversal extended the range to higher spatial frequencies by up to two octaves. There was an increase in VEP delay and a greater degree of discrimination from a control group at higher spatial frequencies. This finding is discussed in the light of previous reports of luminance and checkerboard VEPs in demyelinating optic nerve disease. An attempt is made to relate amplitude changes in various VEP components to contrast sensitivity measurements in this group of patients. PMID:6663312

  14. Engineering non-Hermitian optical potentials for Polariton Condensation

    NASA Astrophysics Data System (ADS)

    Khan, Saeed; Ge, Li; Tureci, Hakan

    We present a theoretical study of incoherently pumped exciton-polariton condensates in general cavity geometries, based on an analysis of the linear non-Hermitian modes of the (optical) pump induced potential. An analytical description is obtained for how the threshold pump power for condensation into a specific mode depends quantitatively on the relative spatial profiles of that mode and the pump. Specifically, we show that for a general pump profile, modes which best organize to balance the amplification from the pump against the repulsive pump potential achieve the lowest threshold power. Reversing this idea, choosing the spatial profile of the pump provides control over which spatial mode condenses at lowest power. Our work hence provides a scheme to engineer non-Hermitian optical potentials for preferential polariton condensation into a specific mode, by an appropriate choice of pump profile. This approach has recently been used to achieve condensation in the flat band of a Lieb chain of micropillar cavities, where the flat band has energy above the ground state and hence cannot be studied in systems in thermal equilibrium.

  15. Disentanglement of Nuclear Medium Effects in the Optical Model Potential

    SciTech Connect

    Arellano, H. F.; Bauge, E.

    2007-10-26

    The microscopic optical model potential for elastic hadron-nucleus scattering is usually represented as the convolution of a two-body effective interaction and the target ground-state mixed density. Traditionally, these convolutions become feasible with the use of simplifying assumptions and the use of the Brueckner-Bethe-Goldstone g-matrix approach for the effective interaction. As a consequence, nuclear medium effects are made explicit in the optical potential as spatial integrals through the bulk of the nucleus[1]. In this contribution we discuss a new and exact approach to track the manifestation of intrinsic nuclear medium effects. Indeed, by examining the structure in momentum and coordinate space of a two-body effective interaction spherically symmetric in its local coordinate, it is demonstrated that it can be expressed as the sum of two distinctive contributions. One of them is a medium-independent term and the other is functionally- and exclusively-proportional to the gradient of the reduced matrix element. As a result, the unabridged optical potential in momentum space becomes expressed as the sum of a medium-free and medium-dependent contributions. The latter depends exclusively on the variations of the effective interaction with respect to the density, being modulated by the gradient of the density ({rho}{sup '}{partial_derivative}/{partial_derivative}{rho}). This feature implies an enhancement of the intrinsic medium effects in the nuclear surface and suppression in the saturated volume. The manifestation of these features will be discussed in the context nucleon-nucleus elastic scattering at low and intermediate energies.

  16. Measuring spin correlations in optical lattices using superlattice potentials

    SciTech Connect

    Pedersen, K. G. L.; Andersen, B. M.; Soerensen, A. S.; Bruun, G. M.; Syljuaasen, O. F.

    2011-10-15

    We suggest two experimental methods for probing both short- and long-range spin correlations of atoms in optical lattices using superlattice potentials. The first method involves an adiabatic doubling of the periodicity of the underlying lattice to probe neighboring singlet (triplet) correlations for fermions (bosons) by the occupation of the resulting vibrational ground state. The second method utilizes a time-dependent superlattice potential to generate spin-dependent transport by any number of prescribed lattice sites, and probes correlations by the resulting number of doubly occupied sites. For experimentally relevant parameters, we demonstrate how both methods yield large signatures of antiferromagnetic correlations of strongly repulsive fermionic atoms in a single shot of the experiment. Lastly, we show how this method may also be applied to probe d-wave pairing, a possible ground-state candidate for the doped repulsive Hubbard model.

  17. Green's Function Application for Pairing Correlations and the Optical Potential

    NASA Astrophysics Data System (ADS)

    Ding, Dong

    Pairing in asymmetric nuclear matter has been studied incorporating the effect of finite total momentum. We employ the generalized Cooper eigenvalue equation, which can be used to demonstrate the pairing instability and also generates reasonable pairing gaps compared to the traditional Bardeen-Cooper-Schrieffer (BCS) gap equation. From phase space arguments and the resulting strength of the pairing gap, we learn that the Larkin-Ovchinnikov-Fulde-Ferrell phase with a finite total momentum is favored over the conventional phase in asymmetric nuclear matter, but not in symmetric nuclear matter. To address open questions in neutron star cooling, neutron matter pairing gaps of the 1S0 and the 3P2 - 3F2 channels in a wide range of densities have been calculated using three different realistic interactions. Instead of the mean-field BCS procedure, we incorporate the influence of short- and long-range correlations in calculating the pairing gaps. Short-range correlations are treated to include the fragmentation of single-particle states, suppressing the gaps substantially. Long-range correlations dress the pairing interaction via density and spin modes, and provide a smaller correction. The results provide input for neutron-star cooling scenarios and are parametrized in a user friendly way. The results are of particular relevance in view of the recent observational data on Cassiopeia A. To study the nucleon-nucleus scattering problem in an ab-initio way, the optical potential in the momentum vector basis beyond the mean-field has been calculated employing the T x rho folding as the first step of the self-consistent Green's function method. The deuteron pole structure of T- matrix has been properly avoided using the spectral functions from the dispersive optical model. A comparison of the resulting real and imaginary part of the self-energy at 100 MeV with the corresponding dispersive-optical-model potentials shows reasonable agreement.

  18. Energy levels and crystal field parameters for Nd3+ ions in BaY2F8, LiKYF5, and K2YF5 single crystals.

    PubMed

    Karbowiak, M; Gnutek, P; Rudowicz, C

    2012-02-15

    The available experimental energy levels of Nd(3+) ions doped into single crystals of BaY(2)F(8), LiKYF(5), and K(2)YF(5), which exhibit low site symmetry, are reanalyzed. A combined approach based on the ascent/descent in symmetry (ADS) method, the superposition model (SPM) analysis, and the pseudosymmetry axes method (PAM) is utilized to extract the crystal field (CF) parameters, B(kq), from experimental spectra. Corresponding sets of the free-ion parameters are also fitted. The crystallographic data are used to establish the axis systems most appropriate for approximation of the actual monoclinic C(2) site symmetry to higher orthorhombic D(2) and tetragonal D(4) symmetry used in CF calculations for BaY(2)F(8). Similarly, for triclinic C(1) site symmetry in LiKYF(5) and K(2)YF(5) approximation to monoclinic C(2) and orthorhombic D(2) symmetry for LiKYF(5), whereas the monoclinic C(s) symmetry for K(2)YF(5), are considered. It is shown that the C(2v) approximation used previously for K(2)YF(5):Nd(3+) is not suitable. SPM enables to calculate for the unapproximated and idealized polyhedrons YF(8) in a given ion-host system of the combined coordination factors Sg(k,q) expressed in the modified crystallographic axis system CAS* and approximated symmetry adapted axis systems, respectively. The quantities Sg(k,q) serve as input for PAM calculations for independent determination of the axis system appropriate for higher symmetry approximations. The pseudosymmetry axes represent the axis system that reflects most closely the approximated higher symmetry of the nearest ligands in a paramagnetic complex embodied in the 4th-rank CF parameters. The combined ADS/SPM/PAM approach provides sets of starting CF parameters (CFPs) in well-defined axis systems. Multiple fittings starting from different points in the CF parameter space yield converging solutions, thus increasing the reliability of the final optimized solutions, which may be then considered as the global minima. The

  19. Thioborates: potential nonlinear optical materials with rich structural chemistry.

    PubMed

    Lian, Yu-Kun; Wu, Li-Ming; Chen, Ling

    2017-03-27

    Nonlinear optical (NLO) crystal materials with good performance are urgently needed. Various compounds have been explored to date. Metal chalcogenides and borates are common sources of potential NLO materials with desirable properties, particularly in the IR and UV regions, respectively. However, these two types of crystals have their specific drawbacks. Thioborates, as an emerging system, have unique advantages by combining the merits of borates and sulfides, i.e., the high laser damage thresholds and rich structural diversity of borates with large optical nonlinearity and the favorable transparency range of sulfides. However, only a limited number of thioborates are known. This paper summarizes the known thioborates according to structural motifs that range from zero-dimension to three-dimension, most of which are formed by sharing corners of the basic building units (BS3)(3-) and (BS4)(5-). Although nearly one-third of the known thioborates are noncentrosymmetric, most of their properties, especially their NLO behaviors, are unexplored. Further attempts and additional investigations are required with respect to design syntheses, property improvements and micro-mechanism studies.

  20. Cold atom dynamics in a quantum optical lattice potential.

    PubMed

    Maschler, Christoph; Ritsch, Helmut

    2005-12-31

    We study a generalized cold atom Bose-Hubbard model, where the periodic optical potential is formed by a cavity field with quantum properties. On the one hand, the common coupling of all atoms to the same mode introduces cavity-mediated long-range atom-atom interactions, and, on the other hand, atomic backaction on the field introduces atom-field entanglement. This modifies the properties of the associated quantum phase transitions and allows for new correlated atom-field states, including superposition of different atomic quantum phases. After deriving an approximative Hamiltonian including the new long-range interaction terms, we exhibit central physical phenomena at generic configurations of few atoms in few wells. We find strong modifications of population fluctuations and next-nearest-neighbor correlations near the phase transition point.

  1. A new measurement of the 7Li(d,p)8Li cross section and consequences for 7Be(p,γ)8B

    NASA Astrophysics Data System (ADS)

    Weissman, L.; Broude, C.; Goldring, G.; Hadar, R.; Hass, M.; Schwamm, F.; Shaanan, M.

    1998-02-01

    A novel scheme for measuring the cross section of the 7Be(p,γ)8B reaction, the major source of high energy neutrinos from the sun, is presented. The scheme involves a strictly uniform particle beam and overcomes some of the recognized experimental uncertainties of previous measurements. A new measurement of σ[7Li(d,p)8Li] has been carried out using this setup, and the present value of σ[7Li(d,p)8Li] = 155(8) mb at the top of the Ed(lab.) = 776 keV resonance is compared with previous measurements. A new issue regarding both the (d,p) and (p,γ) reactions has been examined: reaction-product nuclei which are backscattered out of the target. Measurements and simulations carried out in the course of this investigation are presented and discussed in the context of possible effects on the measured cross sections of these reactions.

  2. Spectral singularity in confined PT symmetric optical potential

    SciTech Connect

    Sinha, Anjana; Roychoudhury, R.

    2013-11-15

    We present an analytical study for the scattering amplitudes (Reflection ‖R‖ and Transmission ‖T‖), of the periodic PT symmetric optical potential V(x)=W{sub 0}cos{sup 2}x+iV{sub 0}sin2x confined within the region 0 ⩽x⩽L, embedded in a homogeneous medium having uniform potential W{sub 0}. The confining length L is considered to be some integral multiple of the period π. We give some new and interesting results. Scattering is observed to be normal (‖T‖{sup 2}⩽ 1, ‖R‖{sup 2}⩽ 1) for V{sub 0}⩽ 0.5, when the above potential can be mapped to a Hermitian potential by a similarity transformation. Beyond this point (V{sub 0} > 0.5) scattering is found to be anomalous (‖T‖{sup 2}, ‖R‖{sup 2} not necessarily ⩽1). Additionally, in this parameter regime of V{sub 0}, one observes infinite number of spectral singularities E{sub SS} at different values of V{sub 0}. Furthermore, for L= 2nπ, the transition point V{sub 0}= 0.5 shows unidirectional invisibility with zero reflection when the beam is incident from the absorptive side (Im[V(x)] < 0) but with finite reflection when the beam is incident from the emissive side (Im[V(x)] > 0), transmission being identically unity in both cases. Finally, the scattering coefficients ‖R‖{sup 2} and ‖T‖{sup 2} always obey the generalized unitarity relation : ‖T|{sup 2}−1|=√(|R{sub R}|{sup 2}|R{sub L}|{sup 2}), where subscripts R and L stand for right and left incidence, respectively.

  3. Coupled counterrotating polariton condensates in optically defined annular potentials

    PubMed Central

    Dreismann, Alexander; Cristofolini, Peter; Balili, Ryan; Christmann, Gabriel; Pinsker, Florian; Berloff, Natasha G.; Hatzopoulos, Zacharias; Savvidis, Pavlos G.; Baumberg, Jeremy J.

    2014-01-01

    Polariton condensates are macroscopic quantum states formed by half-matter half-light quasiparticles, thus connecting the phenomena of atomic Bose–Einstein condensation, superfluidity, and photon lasing. Here we report the spontaneous formation of such condensates in programmable potential landscapes generated by two concentric circles of light. The imposed geometry supports the emergence of annular states that extend up to 100 μm, yet are fully coherent and exhibit a spatial structure that remains stable for minutes at a time. These states exhibit a petal-like intensity distribution arising due to the interaction of two superfluids counterpropagating in the circular waveguide defined by the optical potential. In stark contrast to annular modes in conventional lasing systems, the resulting standing wave patterns exhibit only minimal overlap with the pump laser itself. We theoretically describe the system using a complex Ginzburg–Landau equation, which indicates why the condensate wants to rotate. Experimentally, we demonstrate the ability to precisely control the structure of the petal condensates both by carefully modifying the excitation geometry as well as perturbing the system on ultrafast timescales to reveal unexpected superfluid dynamics. PMID:24889642

  4. The potential of optical coherence tomography in meniscal tear characterization

    NASA Astrophysics Data System (ADS)

    Ling, Hang-yin; Guo, Shuguang; Thieman, Kelley M.; Wise, Brent T.; Pozzi, Antonio; Xie, Huikai; Horodyski, MaryBeth

    2009-02-01

    Meniscal tear is one of the most common knee injuries leading to pain and discomfort. Partial and total meniscectomies have been widely used to treat the avascular meniscal injuries in which tears do not heal spontaneously. However, the meniscectomies would cause an alteration of the tibiofemoral contact mechanics resulting in progressive osteoarthritis (OA). To mitigate the progression of OA, maximal preservation of meniscal tissue is recommended. The clinical challenge is deciding which meniscal tears are amenable to repair and which part of damaged tissues should be removed. Current diagnosis techniques such as arthroscopy and magnetic resonance imaging can provide macrostructural information of menisci, but the microstructural changes that occur prior to the observable meniscal tears cannot be identified by these techniques. Serving as a nondestructive optical biopsy, optical coherence tomography (OCT), a newly developed imaging modality, can provide high resolution, cross-sectional images of tissues and has been shown its capabilty in arthroscopic evaulation of articular cartilage. Our research was to demonstrate the potential of using OCT for nondestructive characterization of the histopathology of different types of meniscal tears from clinical cases in dogs, providing a fundamental understanding of the failure mechanism of meniscal tears. First, cross-sectional images of torn canine menisci obtained from the OCT and scanning electronic microscopy (SEM) were be compared. By studying the organization of collegan fibrils in torn menisci from the SEM images, the feasibility of using OCT to characterize the organization of collegan fibrils was elucidated. Moreover, the crack size of meniscal tears was quantatitively measured from the OCT images. Changes in the crack size of the tear may be useful for understanding the failure mechanism of meniscal tears.

  5. Label-free optical detection of action potential in mammalian neurons

    PubMed Central

    Batabyal, Subrata; Satpathy, Sarmishtha; Bui, Loan; Kim, Young-Tae; Mohanty, Samarendra; Bachoo, Robert; Davé, Digant P.

    2017-01-01

    We describe an optical technique for label-free detection of the action potential in cultured mammalian neurons. Induced morphological changes due to action potential propagation in neurons are optically interrogated with a phase sensitive interferometric technique. Optical recordings composed of signal pulses mirror the electrical spike train activity of individual neurons in a network. The optical pulses are transient nanoscale oscillatory changes in the optical path length of varying peak magnitude and temporal width. Exogenous application of glutamate to cortical neuronal cultures produced coincident increase in the electrical and optical activity; both were blocked by application of a Na-channel blocker, Tetrodotoxin. The observed transient change in optical path length in a single optical pulse is primarily due to physical fluctuations of the neuronal cell membrane mediated by a yet unknown electromechanical transduction phenomenon. Our analysis suggests a traveling surface wave in the neuronal cell membrane is responsible for the measured optical signal pulses. PMID:28856044

  6. Optical vortices as potential indicators of biophysical dynamics

    NASA Astrophysics Data System (ADS)

    Majumdar, Anindya; Kirkpatrick, Sean J.

    2017-03-01

    Laser speckle patterns are granular patterns produced as a result of random interference of light waves. Optical vortices (OVs) are phase singularities in such speckle fields, characterized by zero intensity and an undefined phase. Decorrelation of the speckle fields causes these OVs to move in both time and space. In this work, a variety of parameters of these OVs have been studied. The speckle fields were simulated to undergo three distinct decorrelation behaviors- Gaussian, Lorentzian and constant decorrelations. Different decorrelation behaviors represent different dynamics. For example, Lorentzian and Gaussian decorrelations represent Brownian and ordered motions, respectively. Typical dynamical systems in biophysics are generally argued to be a combination of these. For each of the decorrelation behaviors under study, the vortex trails were tracked while varying the rate of decorrelation. Parameters such as the decorrelation length, average trail length and the deviation of the vortices as they traversed in the speckle field, were studied. Empirical studies were also performed to define the distinction between trails arising from different speckle decorrelation behaviors. The initial studies under stationary speckle fields were followed up by similar studies on shifting fields. A new idea to employ Poincaŕe plots in speckle analysis has also been introduced. Our studies indicate that tracking OVs can be a potential method to study cell and tissue dynamics.

  7. The potential of optical coherence tomography for diagnosing meniscal pathology

    NASA Astrophysics Data System (ADS)

    Hang-Yin Ling, Carrie; Pozzi, Antonio; Thieman, Kelley M.; Tonks, Catherine A.; Guo, Shuguang; Xie, Huikai; Horodyski, MaryBeth

    2010-04-01

    Meniscal tears are often associated with anterior cruciate ligament (ACL) injury and may lead to pain and discomfort in humans. Maximal preservation of meniscal tissue is highly desirable to mitigate the progression of osteoarthritis. Guidelines of which meniscal tears are amenable to repair and what part of damaged tissues should be removed are elusive and lacking consensus. Images of microstructural changes in meniscus would potentially guide the surgeons to manage the meniscal tears better, but the resolution of current diagnostic techniques is limited for this application. In this study, we demonstrated the feasibility of using optical coherence tomography (OCT) for the diagnosis of meniscal pathology. Torn medial menisci were collected from dogs with ACL insufficiency. The torn meniscus was divided into three tissue samples and scanned by OCT and scanning electron microscopy (SEM). OCT and SEM images of torn menisci were compared. Each sample was evaluated for gross and microstructural abnormalities and reduction or loss of birefringence from the OCT images. The abnormalities detected with OCT were described for each type of tear. OCT holds promise in non-destructive and fast assessment of microstructural changes and tissue birefringence of meniscal tears. Future development of intraoperative OCT may help surgeons in the decision making of meniscal treatment.

  8. The potential optical coherence tomography in tooth bleaching quantitative assessment

    NASA Astrophysics Data System (ADS)

    Ni, Y. R.; Guo, Z. Y.; Shu, S. Y.; Zeng, C. C.; Zhong, H. Q.; Chen, B. L.; Liu, Z. M.; Bao, Y.

    2011-12-01

    In this paper, we report the outcomes from a pilot study on using OCT functional imaging method to evaluate and quantify color alteration in the human teeth in vitro. The image formations of the dental tissues without and with treatment 35% hydrogen peroxide were obtained by an OCT system at a 1310 nm central wavelength. One parameter for the quantification of optical properties from OCT measurements is introduced in our study: attenuate coefficient (μ). And the attenuate coefficient have significant decrease ( p < 0.001) in dentine as well as a significant increase ( p < 0.001) in enamel was observed during tooth bleaching process. From the experimental results, it is found that attenuate coefficient could be useful to assess color alteration of the human tooth samples. OCT has a potential to become an effective tool for the assessment tooth bleaching. And our experiment offer a now method to evaluate color change in visible region by quantitative analysis of the infrared region information from OCT.

  9. Interrelationship of optical coherence tomography and multifocal visual-evoked potentials after optic neuritis.

    PubMed

    Klistorner, Alexander; Arvind, Hemamalini; Garrick, Raymond; Graham, Stuart L; Paine, Mark; Yiannikas, Con

    2010-05-01

    Acute optic neuritis (ON) is often followed by recovery of visual function. Although this recovery is mainly attributable to resolution of the acute inflammation, the redistribution of ion channels along the demyelinated membrane, and subsequent remyelination, part of it may be the result of neural plasticity. In the present study, the interrelationship was examined between structural (retinal nerve fiber layer [RNFL] thickness) and functional (amplitude of multifocal visual evoked potentials [mfVEPs]) measures of the integrity of the visual pathway in the postacute stage of ON, to determine whether there was any evidence of ongoing neural reorganization. Twenty-five subjects with acute unilateral ON underwent serial RNFL thickness measurement and mfVEP recording. The inter-eye asymmetry of both measures was analyzed. In the period between 6 and 12 months, the subjects were considered free of optic disc edema, and that period was used to analyze the structure-function relationship. Twenty control subjects were also examined. There were significant but opposite changes in RNFL thickness and mfVEP amplitude. The average asymmetry of RNFL thickness between affected and fellow eyes increased from 17.5 +/- 11.5 to 21.1 +/- 12.8 microm (P = 0.0003), indicating progressive axonal loss, whereas mfVEP amplitude asymmetry decreased from 46.6 +/- 32.4 to 38.3 +/- 31.1 nV (P = 0.0015), indicating continuous functional recovery. In comparison to the 6-month results, the mfVEP amplitude in the ON eye improved by 17.8%, whereas RNFL thickness decreased by 20.8%. The result remained unchanged regardless of the degree of optic nerve remyelination. The finding of structural-functional discrepancy at the postinflammatory stage may support the concept that neural plasticity contributes to functional recovery after acute ON.

  10. Density dependence of microscopic nucleon optical potential in first order Brueckner theory

    NASA Astrophysics Data System (ADS)

    Saliem, S. M.; Haider, W.

    2002-06-01

    In the present work we apply the lowest order Brueckner theory of infinite nuclear matter to obtain nucleon-nucleus optical potential for p-40Ca elastic scattering at 200 MeV using Urbana V14 soft core internucleon potential. We have investigated the effect of target density on the calculated nucleon-nucleus optical potential. We find that the calculated optical potentials depend quite sensitively on the density distribution of the target nucleus. The important feature is that the real part of calculated central optical potential for all densities shows a wine-bottle-bottom type behaviour at this energy. We also discuss the effect of our new radial dependent effective mass correction. Finally, we compare the prediction of our calculated nucleon optical potential using V14 with the prediction using older hard core Hamada-Johnston internucleon potential for p-40Ca elastic scattering at 200 MeV.

  11. Optical processing architecture and its potential application for digital and analog radiography.

    PubMed

    Liu, H; Xu, J; Fajardo, L L

    1999-04-01

    In this report we introduce the fundamental architectures and the potential applications of optical processing techniques in medical imaging. Three basic optical processing architectures were investigated for digital and analog radiography. The processors consist of a module that converts either the analog or the digital radiograph into a coherent light distribution; a coherent optical processing architecture that performs various mathematical operations; a programmable digital-optical interface and other accessories. Optical frequency filters were implemented for mammographic and other clinical feature enhancement. In medical image processing, digital computers offer the advantages of programmability and flexibility. In contrast, optical processors perform parallel image processing with high speed. Optical processors also offer analog nature, compact size, and cost effectiveness. With technical advances of digital-optical interface devices, the medical image processor, in the foreseeable future, may be a hybrid device, namely, a programmable optical architecture.

  12. Potential for path-average rainfall estimation from combined microwave and optical attenuation measurements

    NASA Astrophysics Data System (ADS)

    Uijlenhoet, R.; Leijnse, H.

    2009-04-01

    On previous occasions we have demonstrated the potential and limitations of both microwave and optical links as path-average rain gauges. In this presentation we investigate the potential of combined microwave and optical attenuation measurements for improved path-average rainfall monitoring through theoretical analysis and numerical experiments.

  13. Nonlinear Optical Properties of Organic and Polymeric Thin Film Materials of Potential for Microgravity Processing Studies

    NASA Technical Reports Server (NTRS)

    Abdeldayem, Hossin; Frazier, Donald O.; Paley, Mark S.; Penn, Benjamin; Witherow, William K.; Bank, Curtis; Shields, Angela; Hicks, Rosline; Ashley, Paul R.

    1996-01-01

    In this paper, we will take a closer look at the state of the art of polydiacetylene, and metal-free phthalocyanine films, in view of the microgravity impact on their optical properties, their nonlinear optical properties and their potential advantages for integrated optics. These materials have many attractive features with regard to their use in integrated optical circuits and optical switching. Thin films of these materials processed in microgravity environment show enhanced optical quality and better molecular alignment than those processed in unit gravity. Our studies of these materials indicate that microgravity can play a major role in integrated optics technology. Polydiacetylene films are produced by UV irradiation of monomer solution through an optical window. This novel technique of forming polydiacetylene thin films has been modified for constructing sophisticated micro-structure integrated optical patterns using a pre-programmed UV-Laser beam. Wave guiding through these thin films by the prism coupler technique has been demonstrated. The third order nonlinear parameters of these films have been evaluated. Metal-free phthalocyanine films of good optical quality are processed in our laboratories by vapor deposition technique. Initial studies on these films indicate that they have excellent chemical, laser, and environmental stability. They have large nonlinear optical parameters and show intrinsic optical bistability. This bistability is essential for optical logic gates and optical switching applications. Waveguiding and device making investigations of these materials are underway.

  14. Determination of astrophysical 7Be(p, γ)8B reaction rates from the 7Li(d, p)8Li reaction

    NASA Astrophysics Data System (ADS)

    Du, XianChao; Guo, Bing; Li, ZhiHong; Pang, DanYang; Li, ErTao; Liu, WeiPing

    2015-06-01

    The 7Be(p, γ)8B reaction plays a central role not only in the evaluation of solar neutrino fluxes but also in the evolution of the first stars. Study of this reaction requires the asymptotic normalization coefficient (ANC) for the virtual decay 8B g.s. → 7Be + p. By using the charge symmetry relation, we obtain this proton ANC with the single neutron ANC of 8Li g.s. →7Li + n, which is determined with the distorted wave Born approximation (DWBA) and adiabatic distorted wave approximation (ADWA) analysis of the 7Li(d, p)8Li angular distribution. The astrophysical S-factors and reaction rates of the direct capture process in the 7Be(p, γ)8B reaction are further deduced at energies of astrophysical relevance. The astrophysical S-factor at zero energy for direct capture, S 17(0), is derived to be (19.9 ± 3.5) eV b in good agreement with the most recent recommended value. The contributions of the 1+ and 3+ resonances to the S-factor and reaction rate are also evaluated. The present result demonstrates that the direct capture dominates the 7Be(p, γ)8B reaction in the whole temperature range. This work provides an independent examination to the current results of the 7Be(p, γ)8B reaction.

  15. β -detected NMR of 8Li+ in Bi, Sb, and the topological insulator Bi0.9Sb0.1

    NASA Astrophysics Data System (ADS)

    MacFarlane, W. A.; Tschense, C. B. L.; Buck, T.; Chow, K. H.; Cortie, D. L.; Hariwal, A. N.; Kiefl, R. F.; Koumoulis, D.; Levy, C. D. P.; McKenzie, I.; McGee, F. H.; Morris, G. D.; Pearson, M. R.; Song, Q.; Wang, D.; Hor, Y. S.; Cava, R. J.

    2014-12-01

    We report the NMR Knight shift and spin-lattice relaxation of 8Li+ implanted ˜100 nm into single crystals of semimetallic Sb, Bi, and topologically insulating Bi0.9Sb0.1. We find small negative shifts (of order 100 ppm) in all three. In the insulator, the shift is nearly temperature independent, while in Bi and Sb it becomes more negative at low temperature without following the bulk susceptibility, suggesting two distinct temperature dependent contributions, possibly from the orbital and spin response. However, a simple model is unable to account for the observed shift. The spin-lattice relaxation differs in both scale and temperature dependence in all three. It is Korringa-like in Bi and remarkably is fastest in the insulating alloy and slowest in Sb with the highest bulk carrier density. These surprising results call for detailed calculations, but phenomenologically demonstrate that β -detected NMR of implanted 8Li+ is sensitive to the magnetic response of low-density carriers. The prospects for depth-resolved studies of conventional and topological surface states at lower implantation energies are good.

  16. Potential for integrated optical circuits in advanced aircraft with fiber optic control and monitoring systems

    NASA Astrophysics Data System (ADS)

    Baumbick, Robert J.

    1991-02-01

    Fiber optic technology is expected to be used in future advanced weapons platforms as well as commercial aerospace applications. Fiber optic waveguides will be used to transmit noise free high speed data between a multitude of computers as well as audio and video information to the flight crew. Passive optical sensors connected to control computers with optical fiber interconnects will serve both control and monitoring functions. Implementation of fiber optic technology has already begun. Both the military and NASA have several programs in place. A cooperative program called FOCSI (Fiber Optic Control System Integration) between NASA Lewis and the NAVY to build environmentally test and flight demonstrate sensor systems for propul sion and flight control systems is currently underway. Integrated Optical Circuits (IOC''s) are also being given serious consideration for use in advanced aircraft sys tems. IOC''s will result in miniaturization and localization of components to gener ate detect optical signals and process them for use by the control computers. In some complex systems IOC''s may be required to perform calculations optically if the technology is ready replacing some of the electronic systems used today. IOC''s are attractive because they will result in rugged components capable of withstanding severe environments in advanced aerospace vehicles. Manufacturing technology devel oped for microelectronic integrated circuits applied to IOC''s will result in cost effective manufacturing. This paper reviews the current FOCSI program and describes the role of IOC''s in FOCSI applications.

  17. Dynamical Green's function and an exact optical potential for electron-molecule scattering including nuclear dynamics

    NASA Astrophysics Data System (ADS)

    Brand, Joachim; Cederbaum, Lorenz S.; Meyer, Hans-Dieter

    1999-10-01

    We derive a rigorous optical potential for electron-molecule scattering including the effects of nuclear dynamics by extending the common many-body Green's function approach to optical potentials beyond the fixed-nuclei limit for molecular targets. Our formalism treats the projectile electron and the nuclear motion of the target molecule on the same footing whereby the dynamical optical potential rigorously accounts for the complex many-body nature of the scattering target. One central result of the present work is that the common fixed-nuclei optical potential is a valid adiabatic approximation to the dynamical optical potential even when projectile and nuclear motion are (nonadiabatically) coupled as long as the scattering energy is well below the electronic excitation thresholds of the target. For extremely low projectile velocities, however, when the cross sections are most sensitive to the scattering potential, we expect the influences of the nuclear dynamics on the optical potential to become relevant. For these cases, a systematic way to improve the adiabatic approximation to the dynamical optical potential is presented that yields nonlocal operators with respect to the nuclear coordinates.

  18. Visual Evoked Potential Recording in a Rat Model of Experimental Optic Nerve Demyelination.

    PubMed

    You, Yuyi; Gupta, Vivek K; Chitranshi, Nitin; Reedman, Brittany; Klistorner, Alexander; Graham, Stuart L

    2015-07-29

    The visual evoked potential (VEP) recording is widely used in clinical practice to assess the severity of optic neuritis in its acute phase, and to monitor the disease course in the follow-up period. Changes in the VEP parameters closely correlate with pathological damage in the optic nerve. This protocol provides a detailed description about the rodent model of optic nerve microinjection, in which a partial demyelination lesion is produced in the optic nerve. VEP recording techniques are also discussed. Using skull implanted electrodes, we are able to acquire reproducible intra-session and between-session VEP traces. VEPs can be recorded on individual animals over a period of time to assess the functional changes in the optic nerve longitudinally. The optic nerve demyelination model, in conjunction with the VEP recording protocol, provides a tool to investigate the disease processes associated with demyelination and remyelination, and can potentially be employed to evaluate the effects of new remyelinating drugs or neuroprotective therapies.

  19. Intracoronary optical diagnostics current status, limitations, and potential.

    PubMed

    Lowe, Harry C; Narula, Jagat; Fujimoto, James G; Jang, Ik-Kyung

    2011-12-01

    Optical coherence tomography (OCT), is a novel intravascular imaging modality analogous to intravascular ultrasound but uses light instead of sound. This review details the background, development, and status of current investigation using OCT, and discusses advantages, limitations, and likely future developments. It provides indications for possible future clinical use, and places OCT in the context of current intravascular imaging in what is a rapidly changing field of investigation. Copyright © 2011 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  20. Testing Potential New Sites for Optical Telescopes in Australia

    NASA Astrophysics Data System (ADS)

    Hotan, C. E.; Tingay, S. J.; Glazebrook, K.

    2013-01-01

    In coming years, Australia may find the need to build new optical telescopes to continue local programmes, contribute to global survey projects, and form a local multi-wavelength connection for the new radio telescopes being built. In this study, we refine possible locations for a new optical telescope by studying remotely sensed meteorological infrared data to ascertain expected cloud coverage rates across Australia, and combine these data with a digital elevation model using a geographic information system. We find that the best sites within Australia for building optical telescopes are likely to be on the highest mountains in the Hamersley Range in northwest Western Australia, while the MacDonnell Ranges in the Northern Territory may also be appropriate. We believe that similar seeing values to Siding Spring should be obtainable and with significantly more observing time at the identified sites. We expect to find twice as many clear nights as at current telescope sites. These sites are thus prime locations for future on-site testing.

  1. Mapping two-dimension trapping potential of nanoparticles in an optical trap

    NASA Astrophysics Data System (ADS)

    Fu, Jinxin; Hu, Yi; Zhou, Liangcheng; Lim, Min Yao; Goleb, Melissa; Zhan, Qiwen; Ou-Yang, H. Daniel

    2013-06-01

    Combining confocal microscopy and optical tweezers, we map out the spatial distribution of the particle concentrations of quantum dots, fluorescent HIV pseudo virus particles and polystyrene nanospheres in an optical trap. By analyzing the Boltzmann distribution of local particle concentrations, we obtain the two-dimension single particle trapping potential profile at the center of the optical trap in the direction perpendicular to the beam propagation. We compare the trapping potential energies of pseudo HIV vesicles and same-sized polystyrene spheres. We also compare the trapping potential energy of polystyrene spheres of a focused Gaussian beam and two modes of cylindrical vector beams.

  2. Design and use of an "optrode" for optical recordings of cardiac action potentials.

    PubMed

    Neunlist, M; Zou, S Z; Tung, L

    1992-04-01

    An optical method was used to measure action potentials from frog ventricle, in vitro, under normal physiological conditions with 0.5-1 mM Ca2+ Ringer's solution. The approach presented in this paper involves a portable fluorimeter coupled to a multimode optical fiber running into a glass pipette ("optrode") to carry both excitation light to and fluorescence from the ventricle stained with the voltage sensitive dye di-4-ANEPPS. A suction technique was used to stabilize the optrode-tissue interface, significantly reducing motion artifacts from the beating ventricle. The typical fractional change in fluorescence intensity for an action potential was -9%. The optical recordings faithfully reproduced membrane action potentials as measured with microelectrode recordings. To confirm further the validity of our method we studied the effect of an increasing stimulation rate on the optical action potential. The amplitude of the action potential did not increase, and the change in action potential duration was similar to published results obtained with microelectrode recordings, suggesting that our optical action potentials are relatively free of motion artifacts. Finally, our optical recordings suggest that during anodal and cathodal point stimulation, the time course of membrane potential differs from that predicted simply by a passive cable model.

  3. Optical stimulation of the prostate nerves: A potential diagnostic technique

    NASA Astrophysics Data System (ADS)

    Tozburun, Serhat

    There is wide variability in sexual potency rates (9--86%) after nerve-sparing prostate cancer surgery due to limited knowledge of the location of the cavernous nerves (CN's) on the prostate surface, which are responsible for erectile function. Thus, preservation of the CN's is critical in preserving a man's ability to have spontaneous erections following surgery. Nerve-mapping devices, utilizing conventional Electrical Nerve Stimulation (ENS) techniques, have been used as intra-operative diagnostic tools to assist in preservation of the CN. However, these technologies have proven inconsistent and unreliable in identifying the CN's due to the need for physical contact, the lack of spatial selectivity, and the presence of electrical artifacts in measurements. Optical Nerve Stimulation (ONS), using pulsed infrared laser radiation, is studied as an alternative to ENS. The objective of this study is sevenfold: (1) to develop a laparoscopic laser probe for ONS of the CN's in a rat model, in vivo; (2) to demonstrate faster ONS using continuous-wave infrared laser radiation; (3) to describe and characterize the mechanism of successful ONS using alternative laser wavelengths; (4) to test a compact, inexpensive all-single-mode fiber configuration for optical stimulation of the rat CN studies; (5) to implement fiber optic beam shaping methods for comparison of Gaussian and flat-top spatial beam profiles during ONS; (6) to demonstrate successful ONS of CN's through a thin layer of fascia placed over the nerve and prostate gland; and (7) to verify the experimentally determined therapeutic window for safe and reliable ONS without thermal damage to the CN's by comparison with a computational model for thermal damage. A 5.5-Watt Thulium fiber laser operated at 1870 nm and two pigtailed, single mode, near-IR diode lasers (150-mW, 1455-nm laser and 500-mW, 1550-nm laser) were used for non-contact stimulation of the rat CN's. Successful laser stimulation, as measured by an

  4. Dynamics of optically levitated microparticles in vacuum placed in 2D and 3D optical potentials possessing orbital angular momentum

    NASA Astrophysics Data System (ADS)

    Arita, Yoshihiko; Mazilu, Michael; Chen, Mingzhou; Vettenburg, Tom; Auñón, Juan M.; Wright, Ewan M.; Dholakia, Kishan

    2017-04-01

    We demonstrate the transfer of orbital angular momentum to optically levitated microparticles in vacuum [1]. We prepare two-dimensional and three-dimensional optical potentials. In the former case the microparticle is placed within a Laguerre-Gaussian beam and orbits the annular beam profile with increasing angular velocity as the air drag coefficient is reduced. We explore the particle dynamics as a function of the topological charge of the levitating beam. Our results reveal that there is a fundamental limit to the orbital angular momentum that may be transferred to a trapped particle, dependent upon the beam parameters and inertial forces present. This effect was predicted theoretically [2] and can be understood considering the underlying dynamics arising from the link between the magnitude of the azimuthal index and the beam radius [3]. Whilst a Laguerre-Gaussian beam scales in size with azimuthal index `, recently we have created a "perfect" vortex beam whose radial intensity profile and radius are both independent of topological charge [4, 5]. As the Fourier transform of a perfect vortex yields a Bessel beam. Imaging a perfect vortex, with its subsequent propagation thus realises a complex three dimensional optical field. In this scenario we load individual silica microparticles into this field and observe their trajectories. The optical gradient and scattering forces interplay with the inertial and gravitational forces acting on the trapped particle, including the rotational degrees of freedom. As a result the trapped microparticle exhibits a complex three dimensional motion that includes a periodic orbital motion between the Bessel and the perfect vortex beam. We are able to determine the three dimensional optical potential in situ by tracking the particle. This first demonstration of trapping microparticles within a complex three dimensional optical potential in vacuum opens up new possibilities for fundamental studies of many-body dynamics, mesoscopic

  5. An Optical Survey of Potential Gamma-ray Sources

    NASA Astrophysics Data System (ADS)

    Carpenter, Lisa R.

    2006-12-01

    The EGRET instrument aboard the Compton Gamma-Ray Observatory detected 271 sources. Several objects were identified as "high-confidence" AGN, quasars, and low-confidence AGN. 170 sources remain unidentified (Hartman et al. 1999). Our project is to conduct an optical survey of unidentified sources, looking for evidence of blazar activity that may have been missed by the initial EGRET survey. The method of identifying sources used by the EGRET survey was to search for radio spectra peaking at 5 GHz. Such a spectrum is evidence of blazar-like activity. However, a study by Mattox et al. (1997); Mattox, Hartman & Reimer (2001) concluded that any gamma-ray source with a flux density less than 500 mJy at 5 GHz would be difficult to positively identify. The method described above neglects the possibility that blazar-like sources may be dim at such low frequencies and peak instead at higher frequencies (at least 200 Ghz). It has been hypothesized that sources that behave in this way could very well be counterparts to gamma-ray blazars (Tornikoski et al. 2002; Bloom et al. 1997, 2000). Our goal is to determine the magnitudes of objects in the optical wavelengths and check for evidence of blazar-like activity.

  6. Numerical Green's functions in optical potential calculations for positron scattering from argon and neon

    NASA Technical Reports Server (NTRS)

    Bartschat, K.; Mceachran, R. P.; Stauffer, A. D.

    1990-01-01

    An optical potential method was applied to the calculation of positron scattering from the noble gases in order to determine the effect of open excitation channels on the shape of differential scattering cross sections.

  7. Microscopic optical potential for exotic isotopes from chiral effective field theory

    NASA Astrophysics Data System (ADS)

    Holt, J. W.; Kaiser, N.; Miller, G. A.

    2016-06-01

    We compute the isospin-asymmetry dependence of microscopic optical model potentials from realistic chiral two- and three-body interactions over a range of resolution scales Λ ≃400 -500 MeV. We show that at moderate projectile energies, E =110 -200 MeV, the real isovector part of the optical potential changes sign, a phenomenon referred to as isospin inversion. We also extract the strength and energy dependence of the imaginary isovector optical potential and find no evidence for an analogous phenomenon over the range of energies, E ≤200 MeV, considered in the present work. Finally, we compute for the first time the leading (quadratic) corrections to the Lane parametrization for the isospin-asymmetry dependence of the optical potential and observe an enhanced importance at low scattering energies.

  8. Matter-wave exact periodic solutions in optical lattices with periodic potential

    NASA Astrophysics Data System (ADS)

    Liu, Changfu; Zhu, Aijun

    2013-10-01

    Some special matter-wave periodic solutions for the Gross-Pitaevskii equation with periodic potential in the multidimensional optical lattices, are obtained through restricting parameters and some balance conditions between the optical potentials and interaction energies. The results show that the same type of periodic solutions in the same dimension possesses the same norm but different phases and they are all bounded. Especially, the numerics shows that two class (2+1)-dimensional periodic solutions are stable.

  9. Atomic Landau-Zener tunneling and Wannier-Stark ladders in optical potentials

    SciTech Connect

    Niu, Q.; Zhao, X.; Georgakis, G.; Raizen, M.

    1996-06-01

    We calculate the quantum motion of ultracold atoms in an accelerating optical potential, and show how they may be used to observe Landau-Zener tunneling and Wannier-Stark ladders, two fundamental quantum effects in solid state physics. The optical potential is spatially periodic, yielding an energy spectrum of Bloch bands for the atoms. The acceleration provides an inertial force in the moving frame, emulating an electric force on Bloch electrons. {copyright} {ital 1996 The American Physical Society.}

  10. Quantum Optics in Astrophysics: The Potential of a New Window

    NASA Astrophysics Data System (ADS)

    Solomos, Nikolaos H.

    2006-08-01

    The entire optical astronomy relies upon the detection of light. In this contribution, we put emphasis to the fact that a new window to the universe could be opened with the obvious idea of applying the ...Quantum Theory to describe incoming light Quanta (!). It is clearly the appropriate approach but, nevertheless, it never deemed necessary in main stream astrophysics: Customarily, traditional astronomy not only prefers time-averaged quantities, (although fluctuations in time of a measurement can be a source of information which is getting entirely lost in any time-averaged value) but misses much more information content by continuing to use old semi-classical approaches to treat photon detection processes. Thus, we fail to describe and appreciate in full very important properties of cosmic light, like spatiotemporal coherence. Nevertheless, 45 years of knowledge accumulation in Quantum Optics and technology can now result to the development of instruments capable to extract intimate quantum information scrambled in the incoming optical light fields from celestial sources, provided their ability to detect light emission alterations in the

  11. Microscopic optical model potentials for p-nucleus scattering at intermediate energies

    SciTech Connect

    Hemalatha, M.; Gambhir, Y. K.; Kailas, S.; Haider, W.

    2007-03-15

    A comparative study of the microscopic optical potentials viz., semimicroscopic with extended Jeukenne-Lejeune-Mahaux interaction and microscopic Brueckner theory using Hamada-Johnston as well as Urbana V14 soft-core internucleon interactions, has been carried out. These microscopic optical potentials are compared with that of Dirac phenomenology (DP) for the polarized proton-{sup 40}Ca elastic scattering at 35 MeV and 200 MeV. These potentials have different shapes for 200 MeV below 4 fm. In particular, for the real part of the central potential, only the Dirac phenomenology and the microscopic optical potential calculated with the Hamada-Johnston interaction exhibit the well known wine-bottle-bottom shape. It is found that the calculated observables (cross section, analyzing power and spin rotation function) using these potentials having different shapes, compare well with the experiment.

  12. Thermally Stable Heterocyclic Imines as New Potential Nonlinear Optical Materials

    NASA Technical Reports Server (NTRS)

    Nesterov, Volodymyr V.; Antipin, Mikhail Y.; Nesterov, Vladimir N.; Moore, Craig E.; Cardelino, Beatriz H.; Timofeeva, Tatiana V.

    2004-01-01

    In the course of a search for new thermostable acentric nonlinear optical crystalline materials, several heterocyclic imine derivatives were designed, with the general structure D-pi-A(D'). Introduction of a donor amino group (D') into the acceptor moiety was expected to bring H-bonds into their crystal structures, and so to elevate their melting points and assist in an acentric molecular packing. Six heterocycle-containing compounds of this type were prepared, single crystals were grown for five of them, and these crystals were characterized by X-ray analysis. A significant melting temperature elevation was found for all of the synthesized compounds. Three of the compounds were also found to crystallize in acentric space groups. One of the acentric compounds is built as a three-dimensional H-bonded molecular network. In the other two compounds, with very similar molecular structure, the molecules form one-dimensional H-bonded head-to-head associates (chains). These chains are parallel in two different crystallographic directions and form very unusual interpenetrating chain patterns in an acentric crystal. Two of the compounds crystallized with centrosymmetric molecular packing.

  13. Thermally Stable Heterocyclic Imines as New Potential Nonlinear Optical Materials

    NASA Technical Reports Server (NTRS)

    Nesterov, Volodymyr V.; Antipin, Mikhail Y.; Nesterov, Vladimir N.; Moore, Craig E.; Cardelino, Beatriz H.; Timofeeva, Tatiana V.

    2004-01-01

    In the course of a search for new thermostable acentric nonlinear optical crystalline materials, several heterocyclic imine derivatives were designed, with the general structure D-pi-A(D'). Introduction of a donor amino group (D') into the acceptor moiety was expected to bring H-bonds into their crystal structures, and so to elevate their melting points and assist in an acentric molecular packing. Six heterocycle-containing compounds of this type were prepared, single crystals were grown for five of them, and these crystals were characterized by X-ray analysis. A significant melting temperature elevation was found for all of the synthesized compounds. Three of the compounds were also found to crystallize in acentric space groups. One of the acentric compounds is built as a three-dimensional H-bonded molecular network. In the other two compounds, with very similar molecular structure, the molecules form one-dimensional H-bonded head-to-head associates (chains). These chains are parallel in two different crystallographic directions and form very unusual interpenetrating chain patterns in an acentric crystal. Two of the compounds crystallized with centrosymmetric molecular packing.

  14. Velocity-dependent optical potential for neutron elastic scattering from 1 p -shell nuclei

    NASA Astrophysics Data System (ADS)

    Ghabar, I. N.; Jaghoub, M. I.

    2015-06-01

    Background: The conventional optical model is quite successful in describing the nucleon elastic scattering data from medium and heavy nuclei. However, its success in describing the light 1 p -shell nuclei is somewhat limited. The velocity-dependent optical potential resulted in a significant improvement in describing the elastic angular distributions for light nuclei in the low energy region. Purpose: To extend the formalism of the velocity-dependent potential to higher energies, and to assess its importance in describing neutron elastic scattering data from light 1 p -shell nuclei at high energies. Method: We fit the angular distribution data for neutron elastic scattering from 12C and 16O using (i) the velocity-dependent optical potential and (ii) the conventional optical potential. The results of the two models are then compared. At low energies, we compare our angular distribution fits with the fits of other works that exist in the literature. Furthermore, the total integrated cross sections in addition to the analyzing power are calculated using the velocity-dependent optical potential and compared to the experimental data. Results: The velocity-dependent potential resulted in significant improvements in describing the angular distributions particularly in the large-angle scattering region and for certain energy ranges. This model is important where the experimental data show structural effects from nuclear surface deformations, which are important in light nuclei. Furthermore, the calculated total elastic cross sections and analyzing power are in good agreement with the experimental data. Conclusions: The velocity-dependent potential gives rise to surface-peaked real terms in the optical model. Such terms account, at least partly, for the structural effects seen in the angular distribution data. The energy range over which the surface terms are needed is found to depend on the target nucleus. Other works that have introduced real surface terms in the optical

  15. Optical Stark decelerator for molecules with a traveling potential well

    NASA Astrophysics Data System (ADS)

    Deng, Lianzhong; Hou, Shunyong; Yin, Jianping

    2017-03-01

    We propose a versatile scheme to slow supersonically cooled molecules using a decelerating potential well, obtained by steering a focusing laser beam onto a pair of spinning reflective mirrors under a high-speed brake. The longitudinal motion of molecules in the moving red-detuned light field is analyzed and their corresponding phase-space stability is investigated. Trajectories of C H4 molecules under the influence of the potential well are simulated using the Monte Carlo method. For instance, with a laser beam of power 20 kW focused onto a spot of waist radius 40-100 μm, corresponding to a peak laser intensity on the order of ˜108W /c m2 , a C H4 molecule of ˜250 m /s can be decelerated to ˜10 m /s over a distance of a few centimeters on a time scale of hundreds of microseconds.

  16. Optical properties of retinal tissue and the potential of adaptive optics to visualize retinal ganglion cells in vivo.

    PubMed

    Prasse, Martina; Rauscher, Franziska Georgia; Wiedemann, Peter; Reichenbach, Andreas; Francke, Mike

    2013-08-01

    Many efforts have been made to improve the diagnostic tools used to identify and to estimate the progress of ganglion cell and nerve fibre degeneration in glaucoma. Imaging by optical coherence tomography and measurements of the dimensions of the optic nerve head and the nerve fibre layer in central retinal areas is currently used to estimate the grade of pathological changes. The visualization and quantification of ganglion cells and nerve fibres directly in patients would dramatically improve glaucoma diagnostics. We have investigated the optical properties of cellular structures of retinal tissue in order to establish a means of visualizing and quantifying ganglion cells in the living retina without staining. We have characterized the optical properties of retinal tissue in several species including humans. Nerve fibres, blood vessels, ganglion cells and their cell processes have been visualized at high image resolution by means of the reflection mode of a confocal laser scanning microscope. The potential of adaptive optics in current imaging systems and the possibilities of imaging single ganglion cells non-invasively in patients are discussed.

  17. Label-free optical detection of action potential in mammalian neurons (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Batabyal, Subrata; Satpathy, Sarmishtha; Bui, Loan; Kim, Young-Tae; Mohanty, Samarendra K.; Davé, Digant P.

    2017-02-01

    Electrophysiology techniques are the gold standard in neuroscience for studying functionality of a single neuron to a complex neuronal network. However, electrophysiology techniques are not flawless, they are invasive nature, procedures are cumbersome to implement with limited capability of being used as a high-throughput recording system. Also, long term studies of neuronal functionality with aid of electrophysiology is not feasible. Non-invasive stimulation and detection of neuronal electrical activity has been a long standing goal in neuroscience. Introduction of optogenetics has ushered in the era of non-invasive optical stimulation of neurons, which is revolutionizing neuroscience research. Optical detection of neuronal activity that is comparable to electro-physiology is still elusive. A number of optical techniques have been reported recording of neuronal electrical activity but none is capable of reliably measuring action potential spikes that is comparable to electro-physiology. Optical detection of action potential with voltage sensitive fluorescent reporters are potential alternatives to electrophysiology techniques. The heavily rely on secondary reporters, which are often toxic in nature with background fluorescence, with slow response and low SNR making them far from ideal. The detection of one shot (without averaging)-single action potential in a true label-free way has been elusive so far. In this report, we demonstrate the optical detection of single neuronal spike in a cultured mammalian neuronal network without using any exogenous labels. To the best of our knowledge, this is the first demonstration of label free optical detection of single action potentials in a mammalian neuronal network, which was achieved using a high-speed phase sensitive interferometer. We have carried out stimulation and inhibition of neuronal firing using Glutamate and Tetrodotoxin respectively to demonstrate the different outcome (stimulation and inhibition) revealed in

  18. Assessment of some optical model potentials in predicting neutron cross sections

    SciTech Connect

    Kumar, A.; Young, P.G.; Chadwick, M.B.

    1998-03-01

    Optical model potential parameters play an important role in the evaluation of nuclear data for applied purposes. The IAEA Coordinated Research Program on {open_quotes}Reference Input Parameter Library for Evaluation of Nuclear Data for Application in Nuclear Technology{close_quotes} aims to release a reference input file of various types of parameters for the evaluation of nuclear cross sections using nuclear model codes. Included in the parameter files are a collection of optical model potentials that are available in the literature to evaluate these cross sections. As part of this research program we assess the applicability of these potentials over a range of target mass and projectile energy.

  19. Comparison of global phenomenological and microscopic optical potentials for nuclear data predictions

    SciTech Connect

    Cai, C. ); Shen, Q.; Zhuo, Y. )

    1991-10-01

    In this paper the chi-square ({chi}{sup 2}) values, which represent the degree of agreement between the calculated total, nonelastic, and differential elastic cross sections and their experimental values, are calculated for seven kinds of optical potentials: the phenomenological optimal optical potential (OOP) for a specific element, the global phenomenological optical potentials given by Becchetti and Greenlees (BGP) and by Varner et al. (CH86) for a large number of target nuclei, and the microscopic optical potentials based on conventional Skyrme force (SII and SIII), generalized Skyrme force (GS2), and modified Skyrme force (SKa). Fourteen natural elements (each containing one to four isotopes) are calculated with 12 to 20 neutron incident energies, which are in the 0.1- to 24-MeV energy region for each element. The calculated average total chi-square values are {bar {chi}}{sub OOP}{sup 2} - 0.309, {bar {chi}}{sub BGP}{sup 2} = 0.807, {bar {chi}}{sub CH86}{sup 2} = 0.684, {bar {chi}}{sub GS2}{sup 2} = 0.600, {bar {chi}}{sub SKa}{sup 2} = 0.646, {bar {chi}}{sub SII}{sup 2} = 2.587, and {bar {chi}}{sub SIII}{sup 2} = 1.368. The conclusion is that the microscopic optical potential based on generalized and modified Skyrme force (GS2 and SKa), which has an analytical formalism without any free parameters, is useful in nuclear data calculation and evaluation.

  20. Chemical potential of water from measurements of optic axial angle of zeolites

    USGS Publications Warehouse

    Donald, Eberlein G.; Christ, C.L.

    1968-01-01

    Values of the uncorrected optic axial angle (2H??) of a crystal of the calcium zeolite stellerite (CaAl2Si7O 18 ?? 7H2O) immersed in calcium chloride solutions of known activity of water (aw) are directly proportional to log aw. A general relationship between the chemical potential of water in the crystal and the optic axial angle is obeyed.

  1. Continuous-wave infrared optical nerve stimulation for potential diagnostic applications

    NASA Astrophysics Data System (ADS)

    Tozburun, Serhat; Cilip, Christopher M.; Lagoda, Gwen A.; Burnett, Arthur L.; Fried, Nathaniel M.

    2010-09-01

    Optical nerve stimulation using infrared laser radiation has recently been developed as a potential alternative to electrical nerve stimulation. However, recent studies have focused primarily on pulsed delivery of the laser radiation and at relatively low pulse rates. The objective of this study is to demonstrate faster optical stimulation of the prostate cavernous nerves using continuous-wave (cw) infrared laser radiation for potential diagnostic applications. A thulium fiber laser (λ=1870 nm) is used for noncontact optical stimulation of the rat prostate cavernous nerves in vivo. Optical nerve stimulation, as measured by an intracavernous pressure (ICP) response in the penis, is achieved with the laser operating in either cw mode, or with a 5-ms pulse duration at 10, 20, 30, 40, 50, and 100 Hz. Successful optical stimulation is observed to be primarily dependent on a threshold nerve temperature (42 to 45 °C), rather than an incident fluence, as previously reported. cw optical nerve stimulation provides a significantly faster ICP response time using a lower power (and also less expensive) laser than pulsed stimulation. cw optical nerve stimulation may therefore represent an alternative mode of stimulation for intraoperative diagnostic applications where a rapid response is critical, such as identification of the cavernous nerves during prostate cancer surgery.

  2. Continuous-wave infrared optical nerve stimulation for potential diagnostic applications.

    PubMed

    Tozburun, Serhat; Cilip, Christopher M; Lagoda, Gwen A; Burnett, Arthur L; Fried, Nathaniel M

    2010-01-01

    Optical nerve stimulation using infrared laser radiation has recently been developed as a potential alternative to electrical nerve stimulation. However, recent studies have focused primarily on pulsed delivery of the laser radiation and at relatively low pulse rates. The objective of this study is to demonstrate faster optical stimulation of the prostate cavernous nerves using continuous-wave (cw) infrared laser radiation for potential diagnostic applications. A thulium fiber laser (λ=1870 nm) is used for noncontact optical stimulation of the rat prostate cavernous nerves in vivo. Optical nerve stimulation, as measured by an intracavernous pressure (ICP) response in the penis, is achieved with the laser operating in either cw mode, or with a 5-ms pulse duration at 10, 20, 30, 40, 50, and 100 Hz. Successful optical stimulation is observed to be primarily dependent on a threshold nerve temperature (42 to 45 °C), rather than an incident fluence, as previously reported. cw optical nerve stimulation provides a significantly faster ICP response time using a lower power (and also less expensive) laser than pulsed stimulation. cw optical nerve stimulation may therefore represent an alternative mode of stimulation for intraoperative diagnostic applications where a rapid response is critical, such as identification of the cavernous nerves during prostate cancer surgery.

  3. Nuclear mean field and double-folding model of the nucleus-nucleus optical potential

    NASA Astrophysics Data System (ADS)

    Khoa, Dao T.; Phuc, Nguyen Hoang; Loan, Doan Thi; Loc, Bui Minh

    2016-09-01

    Realistic density dependent CDM3Yn versions of the M3Y interaction have been used in an extended Hartree-Fock (HF) calculation of nuclear matter (NM), with the nucleon single-particle potential determined from the total NM energy based on the Hugenholtz-van Hove theorem that gives rise naturally to a rearrangement term (RT). Using the RT of the single-nucleon potential obtained exactly at different NM densities, the density and energy dependence of the CDM3Yn interactions was modified to account properly for both the RT and observed energy dependence of the nucleon optical potential. Based on a local density approximation, the double-folding model of the nucleus-nucleus optical potential has been extended to take into account consistently the rearrangement effect and energy dependence of the nuclear mean-field potential, using the modified CDM3Yn interactions. The extended double-folding model was applied to study the elastic 12C+12C and 16O+12C scattering at the refractive energies, where the Airy structure of the nuclear rainbow has been well established. The RT was found to affect significantly the real nucleus-nucleus optical potential at small internuclear distances, giving a potential strength close to that implied by the realistic optical model description of the Airy oscillation.

  4. New measurement of the 8Li(α ,n )11B reaction in a lower-energy region below the Coulomb barrier

    NASA Astrophysics Data System (ADS)

    Das, S. K.; Fukuda, T.; Mizoi, Y.; Ishiyama, H.; Miyatake, H.; Watanabe, Y. X.; Hirayama, Y.; Jeong, S. C.; Ikezoe, H.; Matsuda, M.; Nishio, K.; Hashimoto, T.

    2017-05-01

    The 8Li(α ,n )11B reaction is regarded as the key reaction in the inhomogeneous big bang and in type-II supernova nucleosynthesis. Recently, the importance of this reaction to solving the 7Li problem, i.e., the inconsistency between the predicted and the observed primordial 7Li abundances, has also been noted. The most recent cross-section data published by our collaboration group in 2006 [H. Ishiyama et al., Phys. Lett. B 640, 82 (2006), 10.1016/j.physletb.2006.07.036] cover the 0.7- to 2.6-MeV energy region in the center-of-mass system. Here, we present additional data spanning the 0.45- to 1.8-MeV energy region. Thus, the predominant energy region for the big bang nucleosynthesis, corresponding to T9=1 (where T9 is a temperature unit equivalent to 109 K), is almost completely spanned by the previous [H. Ishiyama et al., Phys. Lett. B 640, 82 (2006), 10.1016/j.physletb.2006.07.036] and present results together.

  5. Lithium diffusion in spinel Li4Ti5O12 and LiTi2O4 films detected with 8Liβ -NMR

    NASA Astrophysics Data System (ADS)

    Sugiyama, Jun; Umegaki, Izumi; Uyama, Takeshi; McFadden, Ryan M. L.; Shiraki, Susumu; Hitosugi, Taro; Salman, Zaher; Saadaoui, Hassan; Morris, Gerald D.; MacFarlane, W. Andrew; Kiefl, Robert F.

    2017-09-01

    Diffusion of Li+ in (111) oriented thin films of the spinels Li4Ti5O12 and LiTi2O4 has been studied with 8Liβ -detected NMR in the temperature range between 5 and 310 K. In Li4Ti5O12 , the spin-lattice relaxation rate (1 /T1 ) versus temperature shows a clear maximum around 100 K (=Tmax ) which we attribute to magnetic freezing of dilute Ti3 + local magnetic moments, consistent with the results of magnetization and muon spin relaxation (μ+SR ) measurements. The decrease in 1 /T1 with temperature above Tmax indicates that Li+ starts to diffuse with a thermal activation energy (Ea) of 0.11(1) eV. In LiTi2O4 , on the contrary, as temperature increases from 200 K, 1 /T1 increases monotonically up to 310 K. This suggests that Li also starts to diffuse above 200 K with Ea=0.16 (2 ) eV in LiTi2O4 . Comparison with conventional Li-NMR on Li4Ti5O12 implies that both β -NMR and μ+SR sense short-range Li motion, i.e., a jump diffusion of Li+ to the nearest neighboring sites.

  6. Projectile velocity dependence of emission line polarization degrees following slow Ar{sup 8+}-Li(2s) state-selective electron-capture collisions

    SciTech Connect

    Laulhe, C.; Jacquet, E.; Cremer, G.; Pascale, J.; Boduch, Ph.; Rieger, G.; Chantepie, M.; Lecler, D. ||

    1997-02-01

    The influence of the projectile velocity on the m{sub scr(l)} distributions of the Ar{sup 7+} excited states produced by electron capture during Ar{sup 8+}-Li(2s) collisions is studied experimentally between 1.5 and 4.5 keV amu{sup {minus}1} by measuring the polarization of the emitted light, and theoretically between 1 and 4 keV amu{sup {minus}1} by using the classical trajectory Monte Carlo (CTMC) method. We investigate the 7scr(l){sup {prime}}-8scr(l) and 8scr(l){sup {prime}}-9scr(l) radiative transitions subsequent to the decay of the 8scr(l) and 9scr(l) sublevels of Ar VIII, which are preferentially populated by the single electron capture process. A small but not negligible effect is seen for the experimental polarization ratios relating to transitions from sublevels of large scr(l) values, showing a slight increase of the component parallel to the incident ion beam as the projectile energy increases. Theoretical polarization ratios obtained from CTMC calculated m{sub scr(l)} distributions are in excellent agreement with the measured polarization ratios. Electronic energy curve calculations are then presented in order to discuss these results in terms of dynamical couplings. {copyright} {ital 1997} {ital The American Physical Society}

  7. All optical experimental design for neuron excitation, inhibition, and action potential detection

    NASA Astrophysics Data System (ADS)

    Walsh, Alex J.; Tolstykh, Gleb; Martens, Stacey; Sedelnikova, Anna; Ibey, Bennett L.; Beier, Hope T.

    2016-03-01

    Recently, infrared light has been shown to both stimulate and inhibit excitatory cells. However, studies of infrared light for excitatory cell inhibition have been constrained by the use of invasive and cumbersome electrodes for cell excitation and action potential recording. Here, we present an all optical experimental design for neuronal excitation, inhibition, and action potential detection. Primary rat neurons were transfected with plasmids containing the light sensitive ion channel CheRiff. CheRiff has a peak excitation around 450 nm, allowing excitation of transfected neurons with pulsed blue light. Additionally, primary neurons were transfected with QuasAr2, a fast and sensitive fluorescent voltage indicator. QuasAr2 is excited with yellow or red light and therefore does not spectrally overlap CheRiff, enabling imaging and action potential activation, simultaneously. Using an optic fiber, neurons were exposed to blue light sequentially to generate controlled action potentials. A second optic fiber delivered a single pulse of 1869nm light to the neuron causing inhibition of the evoked action potentials (by the blue light). When used in concert, these optical techniques enable electrode free neuron excitation, inhibition, and action potential recording, allowing research into neuronal behaviors with high spatial fidelity.

  8. Electrical potentials from the eye and optic nerve of Strombus: effects of electrical stimulation of the optic nerve.

    PubMed

    Gillary, H L

    1977-02-01

    1. Photic stimulation of the mature eye of Strombus can evoke in the optic nerve 'on' activity in numerous small afferent fibres and repetitive 'off' bursts of afferent impulses in a smaller number of larger fibres. 2. Synchronous invasion of the eye by electrically evoked impulses in small optic nerve fibres (apparently the 'on' afferents, antidromically activated) can evoke a burst of impulses in the larger 'off' fibres which propagate away from the eye. Invasion of the eye via one branch of optic nerve can evoke an answering burst in another branch. 3. Such electrically evoked bursts are similar to light-evoked 'off' bursts with respect to their impulse composition, their ability to be inhibited by illumination of the eye, and their susceptibility to MgCl2 anaesthesia. 4. Invasion of the eye by a train of repetitive electrically evoked impulses in the absence of photic stimulation can give rise to repetitive 'off' bursts as well as concomitant oscillatory potentials in the eye which are similar to those normally evoked by cessation of a photic stimulus. 5. The electrically evoked 'off' bursts appear to be caused by an excitatory rebound following the cessation of inhibitory synaptic input from photoreceptors which can be antidromically activated by electrical stimulation of the optic nerve. 6. The experimental results suggest that the rhythmic discharge of the 'off' fibres evoked by the cessation of a photic stimulus is mediated by the abrupt decrease of inhibitory synaptic input from the receptors.

  9. Modified Becke-Johnson potential inspired electronic and optical response of CdMoO4

    NASA Astrophysics Data System (ADS)

    Sharma, Khushboo; Meena, Seema; Ahuja, B. L.

    2017-05-01

    We present for the first time the energy bands, density of states and optical response of CdMoO4 using full potential linearized augmented plane wave method with modified Becke-Johnson potential. It is found that this compound has a band gap of 3.68 eV at the Γ point of Brillouin zone. Complex dielectric function response is interpreted in terms of interband transitions in the energy bands. On the basis of optical properties, it is concluded that the CdMoO4 can be used in UV detectors and as a filter of UV radiations.

  10. Visual Evoked Potential Recording in a Rat Model of Experimental Optic Nerve Demyelination

    PubMed Central

    You, Yuyi; Gupta, Vivek K.; Chitranshi, Nitin; Reedman, Brittany; Klistorner, Alexander; Graham, Stuart L.

    2015-01-01

    The visual evoked potential (VEP) recording is widely used in clinical practice to assess the severity of optic neuritis in its acute phase, and to monitor the disease course in the follow-up period. Changes in the VEP parameters closely correlate with pathological damage in the optic nerve. This protocol provides a detailed description about the rodent model of optic nerve microinjection, in which a partial demyelination lesion is produced in the optic nerve. VEP recording techniques are also discussed. Using skull implanted electrodes, we are able to acquire reproducible intra-session and between-session VEP traces. VEPs can be recorded on individual animals over a period of time to assess the functional changes in the optic nerve longitudinally. The optic nerve demyelination model, in conjunction with the VEP recording protocol, provides a tool to investigate the disease processes associated with demyelination and remyelination, and can potentially be employed to evaluate the effects of new remyelinating drugs or neuroprotective therapies. PMID:26273963

  11. A trap potential model investigation of the optical activity induced in dye-DNA intercalation complexes

    NASA Astrophysics Data System (ADS)

    Kamiya, Mamoru

    1988-02-01

    The fundamental features of the optical activity induced in dye-DNA intercalation complexes are studied by application of the trap potential model which is useful to evaluate the induced rotational strength without reference to detailed geometrical information about the intercalation complexes. The specific effect of the potential depth upon the induced optical activity is explained in terms of the relative magnitudes of the wave-phase and helix-phase variations in the path of an electron moving on a restricted helical segment just like an exciton trapped around the dye intercalation site. The parallel and perpendicular components of the induced rotational strength well reflect basic properties of the helicity effects about the longitudinal and tangential axes of the DNA helical cylinder. The trap potential model is applied to optimize the potential parameters so as to reproduce the ionic strength effect upon the optical activity induced to proflavine-DNA intercalation complexes. From relationships between the optimized potential parameters and ionic strengths, it is inferred that increase in the ionic strength contributes to the optical activity induced by the nearest-neighbour interaction between intercalated proflavine and DNA base pairs.

  12. Concurrent application of TMS and near-infrared optical imaging: methodological considerations and potential artifacts.

    PubMed

    Parks, Nathan A

    2013-09-19

    The simultaneous application of transcranial magnetic stimulation (TMS) with non-invasive neuroimaging provides a powerful method for investigating functional connectivity in the human brain and the causal relationships between areas in distributed brain networks. TMS has been combined with numerous neuroimaging techniques including, electroencephalography (EEG), functional magnetic resonance imaging (fMRI), and positron emission tomography (PET). Recent work has also demonstrated the feasibility and utility of combining TMS with non-invasive near-infrared optical imaging techniques, functional near-infrared spectroscopy (fNIRS) and the event-related optical signal (EROS). Simultaneous TMS and optical imaging affords a number of advantages over other neuroimaging methods but also involves a unique set of methodological challenges and considerations. This paper describes the methodology of concurrently performing optical imaging during the administration of TMS, focusing on experimental design, potential artifacts, and approaches to controlling for these artifacts.

  13. Concurrent application of TMS and near-infrared optical imaging: methodological considerations and potential artifacts

    PubMed Central

    Parks, Nathan A.

    2013-01-01

    The simultaneous application of transcranial magnetic stimulation (TMS) with non-invasive neuroimaging provides a powerful method for investigating functional connectivity in the human brain and the causal relationships between areas in distributed brain networks. TMS has been combined with numerous neuroimaging techniques including, electroencephalography (EEG), functional magnetic resonance imaging (fMRI), and positron emission tomography (PET). Recent work has also demonstrated the feasibility and utility of combining TMS with non-invasive near-infrared optical imaging techniques, functional near-infrared spectroscopy (fNIRS) and the event-related optical signal (EROS). Simultaneous TMS and optical imaging affords a number of advantages over other neuroimaging methods but also involves a unique set of methodological challenges and considerations. This paper describes the methodology of concurrently performing optical imaging during the administration of TMS, focusing on experimental design, potential artifacts, and approaches to controlling for these artifacts. PMID:24065911

  14. Derivation of an optical potential for statically deformed rare-earth nuclei from a global spherical potential

    SciTech Connect

    Nobre, G. P. A.; Palumbo, A.; Herman, M.; Brown, D.; Hoblit, S.; Dietrich, F. S.

    2015-02-25

    The coupled-channel theory is a natural way of treating nonelastic channels, in particular those arising from collective excitations characterized by nuclear deformations. A proper treatment of such excitations is often essential to the accurate description of experimental nuclear-reaction data and to the prediction of a wide variety of scattering observables. Stimulated by recent work substantiating the near validity of the adiabatic approximation in coupled-channel calculations for scattering on statically deformed nuclei, we explore the possibility of generalizing a global spherical optical model potential (OMP) to make it usable in coupled-channel calculations on this class of nuclei. To do this, we have deformed the Koning-Delaroche global spherical potential for neutrons, coupling a sufficient number of states of the ground state band to ensure convergence. We present an extensive study of the effects of collective couplings and nuclear deformations on integrated cross sections as well as on angular distributions for neutron-induced reactions on statically deformed nuclei in the rare-earth region. We choose isotopes of three rare-earth elements (Gd, Ho, W), which are known to be nearly perfect rotors, to exemplify the results of the proposed method. Predictions from our model for total, elastic and inelastic cross sections, as well as for elastic and inelastic angular distributions, are in reasonable agreement with measured experimental data. In conclusion, these results suggest that the deformed Koning-Delaroche potential provides a useful regional neutron optical potential for the statically deformed rare earth nuclei.

  15. Advances in Optical Adjunctive Aids for Visualisation and Detection of Oral Malignant and Potentially Malignant Lesions

    PubMed Central

    Bhatia, Nirav; Lalla, Yastira; Vu, An N.; Farah, Camile S.

    2013-01-01

    Traditional methods of screening for oral potentially malignant disorders and oral malignancies involve a conventional oral examination with digital palpation. Evidence indicates that conventional examination is a poor discriminator of oral mucosal lesions. A number of optical aids have been developed to assist the clinician to detect oral mucosal abnormalities and to differentiate benign lesions from sinister pathology. This paper discusses advances in optical technologies designed for the detection of oral mucosal abnormalities. The literature regarding such devices, VELscope and Identafi, is critically analysed, and the novel use of Narrow Band Imaging within the oral cavity is also discussed. Optical aids are effective in assisting with the detection of oral mucosal abnormalities; however, further research is required to evaluate the usefulness of these devices in differentiating benign lesions from potentially malignant and malignant lesions. PMID:24078812

  16. Simulation study on compressive laminar optical tomography for cardiac action potential propagation.

    PubMed

    Harada, Takumi; Tomii, Naoki; Manago, Shota; Kobayashi, Etsuko; Sakuma, Ichiro

    2017-04-01

    To measure the activity of tissue at the microscopic level, laminar optical tomography (LOT), which is a microscopic form of diffuse optical tomography, has been developed. However, obtaining sufficient recording speed to determine rapidly changing dynamic activity remains major challenges. For a high frame rate of the reconstructed data, we here propose a new LOT method using compressed sensing theory, called compressive laminar optical tomography (CLOT), in which novel digital micromirror device-based illumination and data reduction in a single reconstruction are applied. In the simulation experiments, the reconstructed volumetric images of the action potentials that were acquired from 5 measured images with random pattern featured a wave border at least to a depth of 2.5 mm. Consequently, it was shown that CLOT has potential for over 200 fps required for the cardiac electrophysiological phenomena.

  17. Vibrational mechanics in an optical lattice: controlling transport via potential renormalization.

    PubMed

    Wickenbrock, A; Holz, P C; Wahab, N A Abdul; Phoonthong, P; Cubero, D; Renzoni, F

    2012-01-13

    We demonstrate theoretically and experimentally the phenomenon of vibrational resonance in a periodic potential, using cold atoms in an optical lattice as a model system. A high-frequency (HF) drive, with a frequency much larger than any characteristic frequency of the system, is applied by phase modulating one of the lattice beams. We show that the HF drive leads to the renormalization of the potential. We used transport measurements as a probe of the potential renormalization. The very same experiments also demonstrate that transport can be controlled by the HF drive via potential renormalization.

  18. Microscopic [ital T]-Violating Optical Potential: Implications for Neutron-Transmission Experiments

    SciTech Connect

    Engel, J.; Gould, C.R.; Hnizdo, V. Department of Physics, North Carolina State University, Raleigh, North Carolina 27695 Triangle Universities Nuclear Laboratory, Durham, North Carolina 27708 Department of Physics and Schonland Research Centre for Nuclear Sciences, University of the Witwatersrand, Johannesburg, 2050 )

    1994-12-26

    We derive a [ital T]-violating [ital P]-conserving optical potential for neutron-nucleus scattering, starting from a uniquely determined two-body [rho]-exchange interaction with the same symmetry. We then obtain limits on the [ital T]-violating [rho]-nucleon coupling [ital [bar g

  19. Behavior of a new type quantum accelerator mode in phase-modulated optical potential

    NASA Astrophysics Data System (ADS)

    Lam, Wakun; Wimberger, Sandro; Dadras, Siamak; Ni, Jiating; Summy, Gil

    2015-05-01

    It has been shown that the delta-kicked rotor (DKR) with a Bose-Einstein Condensate is a powerful model for studying the dynamics of many-body systems. Many efforts based on this model have been made in study of dynamical localization, quantum accelerator mode (QAM), to name but a few. QAM is a dynamical phenomenon in which the momentum of atoms exposed to a pulsed accelerating optical standing wave manifest linear growth. In many applications, we expect high transport rate to suppress localization. A recent technique utilizing the phase modulation on the optical potential to produce transport islands has been discussed. In this presentation we study the stability of such islands in classical phase space of a modified DKR system in which the phase of the optical potential is modulated by a certain phase on each kick. Numerical simulations testify the existence of QAM even in small phase perturbation. We also investigate the momentum distribution numerically and report a new type of QAM which exposed in stationary optical potential instead. The interesting structure of the area of the transport islands against wide range of dynamical parameters is observed to be quite distinct to the regular one.

  20. Behavior of a new type quantum accelerator mode in phase-modulated optical potential

    NASA Astrophysics Data System (ADS)

    Lam, Wakun; Wimberger, Sandro; Dadras, Siamak; Ni, Jiating; Summy, Gil; Department of Physics, Oklahoma State University Collaboration; Dipartimento di Fisica E Science Della Terra, Università di Parma Collaboration

    2014-05-01

    Many efforts based on this model have been made in study of dynamical localization, quantum accelerator mode (QAM), to name but a few. QAM is a dynamical phenomenon in which the momentum of atoms exposed to a pulsed accelerating optical standing wave manifest linear growth. In many applications, we expect to improve the transport rate and suppress localization. A recent technique utilizing the phase modulation on the optical potential to produce transporting islands [PRE 68, 026209 (2003) and PRA 87, 013631 (2013)] has been discussed. In this presentation we study the stability of such islands in classical phase space of a modified DKR system in which the phase of the optical potential is modulated by a certain phase in each kick. Numerically simulations testify the existence of QAM even in small perturbation on the modulated phase. We also investigate the momentum distribution experimentally and numerically and report a new type of QAM which exposed in stationary optical potential instead. The interesting structure of the area of the transport islands against wide range of dynamical parameters in phase space is observed to be quite distinct to the regular one.

  1. The Optical Flow Technique on the Research of Solar Non-potentiality

    NASA Astrophysics Data System (ADS)

    Liu, Ji-hong; Zhang, Hong-qi

    2010-06-01

    Several optical flow techniques, which have being applied to the researches of solar magnetic non-potentiality recently, have been summarized here. And a few new non-potential parameters which can be derived from them have been discussed, too. The main components of the work are presented as follows: (1) The optical flow techniques refers to a series of new image analyzing techniques arisen recently on the researches of solar magnetic non-potentiality. They mainly include LCT (local correlation tracking), ILCT (inductive equation combining with LCT), MEF (minimum energy effect), DAVE (differential affine velocity estimator) and NAVE (nonlinear affine velocity estimator). Their calculating and applying conditions, merits and deficiencies, all have been discussed detailedly in this work. (2) Benefit from the optical flow techniques, the transverse velocity fields of the magnetic features on the solar surface may be determined by a time sequence of high-quality images currently produced by high-resolution observations either from the ground or in space. Consequently, several new non-potential parameters may be acquired, such as the magnetic helicity flux, the induced electric field in the photosphere, the non-potential magnetic stress (whose area integration is the Lorentz force), etc. Then we can determine the energy flux across the photosphere, and subsequently evaluate the energy budget. Former works on them by small or special samples have shown that they are probably related closely to the erupting events, such as flare, filament eruptions and coronal mass ejections.

  2. Optical coherence tomography for detection of compound action potential in Xenopus Laevis sciatic nerve

    NASA Astrophysics Data System (ADS)

    Troiani, Francesca; Nikolic, Konstantin; Constandinou, Timothy G.

    2016-03-01

    Due to optical coherence tomography (OCT) high spatial and temporal resolution, this technique could be used to observe the quick changes in the refractive index that accompany action potential. In this study we explore the use of time domain Optical Coherence Tomography (TD-OCT) for real time action potential detection in ex vivo Xenopus Laevis sciatic nerve. TD-OCT is the easiest and less expensive OCT technique and, if successful in detecting real time action potential, it could be used for low cost monitoring devices. A theoretical investigation into the order of magnitude of the signals detected by a TD-OCT setup is provided by this work. A linear dependence between the refractive index and the intensity changes is observed and the minimum SNR for which the setup could work is found to be SNR = 2 x 104.

  3. The {sup 6}He Optical Potential at energies around the Coulomb barrier

    SciTech Connect

    Fernandez-Garcia, J. P.; Alvarez, M. A. G.; Moro, A. M.

    2010-04-26

    We present an Optical Model (OM) study of {sup 6}He on {sup 208}Pb elastic scattering data, measured at laboratory energies around the Coulomb barrier (E{sub lab} = 14, 16, 18, 22, and 27 MeV)[1]. For the projectile-target bare interaction, we use the microscopic Sao Paulo Potential (SPP). This bare interaction is supplemented with a Coulomb Dipole Polarization (CDP) potential, as well as a diffuse complex Woods-Saxon potential. Four-body Continuum-Discretized-Coupled-Channels (CDCC) calculations have been performed in order to support the optical model analysis. We have also studied the alpha channel, which is the dominant reaction process. In the analysis of this channel, we compare the angular and energy distributions of the alpha particles measured at 22 MeV, with Distorted Wave Born Approximation (DWBA) calculations.

  4. Red blood cell membrane viscoelasticity, agglutination and zeta potential measurements with double optical tweezers

    NASA Astrophysics Data System (ADS)

    Fontes, Adriana; Fernandes, Heloise P.; Barjas-Castro, Maria L.; de Thomaz, André A.; de Ysasa Pozzo, Liliana; Barbosa, Luiz C.; Cesar, Carlos L.

    2006-02-01

    The red blood cell (RBC) viscoelastic membrane contains proteins and glycolproteins embedded in, or attached, to a fluid lipid bilayer and are negatively charged, which creates a repulsive electric (zeta) potential between the cells and prevents their aggregation in the blood stream. There are techniques, however, to decrease the zeta potential to allow cell agglutination which are the basis of most of the tests of antigen-antibody interactions in blood banks. This report shows the use of a double optical tweezers to measure RBC membrane viscosity, agglutination and zeta potential. In our technique one of the optical tweezers trap a silica bead that binds strongly to a RBC at the end of a RBCs rouleaux and, at the same time, acts as a pico-Newton force transducer, after calibration through its displacement from the equilibrium position. The other optical tweezers trap the RBC at the other end. To measure the membrane viscosity the optical force is measured as a function of the velocity between the RBCs. To measure the adhesion the tweezers are slowly displaced apart until the RBCs disagglutination happens. The RBC zeta potential is measured in two complimentary ways, by the force on the silica bead attached to a single RBC in response to an applied electric field, and the conventional way, by the measurement of terminal velocity of the RBC after released from the optical trap. These two measurements provide information about the RBC charges and, also, electrolytic solution properties. We believe this can improve the methods of diagnosis in blood banks.

  5. Phenomenological optical potential analysis of proton-carbon elastic scattering at 200 MeV

    NASA Technical Reports Server (NTRS)

    Bidasaria, H. B.; Townsend, L. W.

    1982-01-01

    Differential cross sections for 200 MeV protons elastically scattered from C-12 were analyzed utilizing a local, complex, spin-dependent optical potential with a harmonic well radial dependence. Analyses were performed using the WKB and eikonal approximations. For the latter, first-order corrections to he phase shifts were incorporated to account for the spin-orbit contribution. Large disagreement between theory and experiment was observed when the usual Thomas form for the spin-orbit potential was utilized. Substantial improvement was obtained by allowing the parameters in the central and spin-orbit potential terms to vary independently.

  6. Derivation of an optical potential for statically deformed rare-earth nuclei from a global spherical potential

    DOE PAGES

    Nobre, G. P. A.; Palumbo, A.; Herman, M.; ...

    2015-02-25

    The coupled-channel theory is a natural way of treating nonelastic channels, in particular those arising from collective excitations characterized by nuclear deformations. A proper treatment of such excitations is often essential to the accurate description of experimental nuclear-reaction data and to the prediction of a wide variety of scattering observables. Stimulated by recent work substantiating the near validity of the adiabatic approximation in coupled-channel calculations for scattering on statically deformed nuclei, we explore the possibility of generalizing a global spherical optical model potential (OMP) to make it usable in coupled-channel calculations on this class of nuclei. To do this, wemore » have deformed the Koning-Delaroche global spherical potential for neutrons, coupling a sufficient number of states of the ground state band to ensure convergence. We present an extensive study of the effects of collective couplings and nuclear deformations on integrated cross sections as well as on angular distributions for neutron-induced reactions on statically deformed nuclei in the rare-earth region. We choose isotopes of three rare-earth elements (Gd, Ho, W), which are known to be nearly perfect rotors, to exemplify the results of the proposed method. Predictions from our model for total, elastic and inelastic cross sections, as well as for elastic and inelastic angular distributions, are in reasonable agreement with measured experimental data. In conclusion, these results suggest that the deformed Koning-Delaroche potential provides a useful regional neutron optical potential for the statically deformed rare earth nuclei.« less

  7. Potential formalism of optical spatial soliton propagation in a two-photon photovoltaic-photorefractive material under open circuit condition

    NASA Astrophysics Data System (ADS)

    Akhouri, B. P.; Gupta, P. K.

    2014-04-01

    Propagation characteristics of optical spatial solitons in a two-photon photovoltaic-photorefractive medium under open circuit condition have been investigated using the formalism of a particle in a potential well. Optical nonlinearity has been evaluated using Castro-Camus model. Variational formalism has been employed to investigate the resulting modified nonlinear Schrödinger equation. Potential formalism has been examined to identify localized optical spatial solitons.

  8. Bose-Einstein condensation in large time-averaged optical ring potentials

    NASA Astrophysics Data System (ADS)

    Bell, Thomas A.; Glidden, Jake A. P.; Humbert, Leif; Bromley, Michael W. J.; Haine, Simon A.; Davis, Matthew J.; Neely, Tyler W.; Baker, Mark A.; Rubinsztein-Dunlop, Halina

    2016-03-01

    Interferometric measurements with matter waves are established techniques for sensitive gravimetry, rotation sensing, and measurement of surface interactions, but compact interferometers will require techniques based on trapped geometries. In a step towards the realisation of matter wave interferometers in toroidal geometries, we produce a large, smooth ring trap for Bose-Einstein condensates using rapidly scanned time-averaged dipole potentials. The trap potential is smoothed by using the atom distribution as input to an optical intensity correction algorithm. Smooth rings with a diameter up to 300 μm are demonstrated. We experimentally observe and simulate the dispersion of condensed atoms in the resulting potential, with good agreement serving as an indication of trap smoothness. Under time of flight expansion we observe low energy excitations in the ring, which serves to constrain the lower frequency limit of the scanned potential technique. The resulting ring potential will have applications as a waveguide for atom interferometry and studies of superfluidity.

  9. A Lane consistent optical model potential for nucleon scattering on actinide nuclei with extended coupling

    NASA Astrophysics Data System (ADS)

    Quesada, José Manuel; Capote, Roberto; Soukhovitski, Efrem S.; Chiba, Satoshi

    2016-03-01

    An extension for odd-A actinides of a previously derived dispersive coupledchannel optical model potential (OMP) for 238U and 232Th nuclei is presented. It is used to fit simultaneously all the available experimental databases including neutron strength functions for nucleon scattering on 232Th, 233,235,238U and 239Pu nuclei. Quasi-elastic (p,n) scattering data on 232Th and 238U to the isobaric analogue states of the target nucleus are also used to constrain the isovector part of the optical potential. For even-even (odd) actinides almost all low-lying collective levels below 1 MeV (0.5 MeV) of excitation energy are coupled. OMP parameters show a smooth energy dependence and energy independent geometry.

  10. Optical Potential Parameters of Weakly Bound Nuclear System 17F+13C

    NASA Astrophysics Data System (ADS)

    An, Guang-Peng; Lin, Cheng-Jian; Zhang, Huan-Qiao; Liu, Zu-Hua; Yang, Feng; Zhang, Gao-Long; Zhang, Chun-Lei; Wu, Zhen-Dong; Jia, Fei; Jia, Hui-Ming; Xu, Xin-Xing; Bai, Chun-Lin; Yu, Ning

    2008-12-01

    Elastic scattering angular distributions of the 14N+16O system and the angular distributions of transfer reaction 16O(14N,13 C)17 F at ELab = 76.2 MeV and 57MeV have been measured and calculated by means of the exact finite-range distorted-wave Born approximation with the PTOLEMY code. The optical potential parameters for the weakly bound nuclear system 17F+13 C have been deduced and applied to analyse the elastic scattering angular distributions of the similar systems 17F+12C and 17F+14N which are taken from literature. The result shows that the transfer reaction with stable projectile and target combination can be used as an alternative method to extract the optical potential parameters for the weakly bound nuclear system.

  11. Potential application of far-field superlens in optical critical dimension metrology: a simulation study

    NASA Astrophysics Data System (ADS)

    Li, Wen; Chen, Shuqiang; Deng, Hao

    2017-05-01

    Subwavelength periodic gratings, which are widely used in optical systems, exhibit only zero-order diffraction, owing to a diffraction limit. This limits the resolution of optical critical dimension (OCD) metrology. We propose a method to enhance the diffraction of subwavelength periodic gratings using a far-field superlens (FSL), which has the potential to obtain higher resolution in OCD metrology. All simulations in this study are performed using the rigorous coupled-wave analysis method. An FSL grating structure is developed for verifying the proposed method and for evaluating the role of the incident angle, misalignment, and air gap on the diffraction by the FSL grating structure. The simulation results show that, when overlaid with an FSL, a silicon grating with a period of 100 nm, which evoked zero-order diffraction only, can also evoke first- and second-order diffraction in the case of a large incident angle. Last, the potential application of an FSL in OCD metrology is discussed.

  12. Optical Tweezers as a New Biomedical Tool to Measure Zeta Potential of Stored Red Blood Cells

    PubMed Central

    Silva, Carlos A. L.; Fernandes, Heloise P.; Filho, Milton M.; Lucena, Sheyla C.; Costa, Ana Maria D. N.; Cesar, Carlos L.; Barjas-Castro, Maria L.; Santos, Beate S.; Fontes, Adriana

    2012-01-01

    During storage, red blood cells (RBCs) for transfusion purposes suffer progressive deterioration. Sialylated glycoproteins of the RBC membrane are responsible for a negatively charged surface which creates a repulsive electrical zeta potential. These charges help prevent the interaction between RBCs and other cells, and especially among each RBCs. Reports in the literature have stated that RBCs sialylated glycoproteins can be sensitive to enzymes released by leukocyte degranulation. Thus, the aim of this study was, by using an optical tweezers as a biomedical tool, to measure the zeta potential in standard RBCs units and in leukocyte reduced RBC units (collected in CPD-SAGM) during storage. Optical tweezers is a sensitive tool that uses light for measuring cell biophysical properties which are important for clinical and research purposes. This is the first study to analyze RBCs membrane charges during storage. In addition, we herein also measured the elasticity of RBCs also collected in CPD-SAGM. In conclusion, the zeta potential decreased 42% and cells were 134% less deformable at the end of storage. The zeta potential from leukodepleted units had a similar profile when compared to units stored without leukoreduction, indicating that leukocyte lyses were not responsible for the zeta potential decay. Flow cytometry measurements of reactive oxygen species suggested that this decay is due to membrane oxidative damages. These results show that measurements of zeta potentials provide new insights about RBCs storage lesion for transfusion purposes. PMID:22363729

  13. Optical redox ratio identifies metastatic potential-dependent changes in breast cancer cell metabolism

    PubMed Central

    Alhallak, Kinan; Rebello, Lisa G.; Muldoon, Timothy J.; Quinn, Kyle P.; Rajaram, Narasimhan

    2016-01-01

    The development of prognostic indicators of breast cancer metastatic risk could reduce the number of patients receiving chemotherapy for tumors with low metastatic potential. Recent evidence points to a critical role for cell metabolism in driving breast cancer metastasis. Endogenous fluorescence intensity of nicotinamide adenine dinucleotide (NADH) and flavin adenine dinucleotide (FAD) can provide a label-free method for assessing cell metabolism. We report the optical redox ratio of FAD/(FAD + NADH) of four isogenic triple-negative breast cancer cell lines with varying metastatic potential. Under normoxic conditions, the redox ratio increases with increasing metastatic potential (168FARN>4T07>4T1), indicating a shift to more oxidative metabolism in cells capable of metastasis. Reoxygenation following acute hypoxia increased the redox ratio by 43 ± 9% and 33 ± 4% in the 4T1 and 4T07 cells, respectively; in contrast, the redox ratio decreased 14 ± 7% in the non-metastatic 67NR cell line. These results demonstrate that the optical redox ratio is sensitive to the metabolic adaptability of breast cancer cells with high metastatic potential and could potentially be used to measure dynamic functional changes that are indicative of invasive or metastatic potential. PMID:27895979

  14. Potential for Terahertz/Optical, Two Color Non-linear Sensing of Liquid Biochemical Agents

    DTIC Science & Technology

    2011-05-18

    solutions1,2 in the infrared frequency band. To explore the lowest frequency macromo- lecular modes of biomolecules, which occur at terahertz fre- quencies, in...resonant with elec- tronic excitations and macromolecular vibrations . A configuration that optimizes SDFG in the face of strong terahertz absorption by...REPORT Potential for terahertz /optical, two color non-linear sensing of liquid biochemical agents 14. ABSTRACT 16. SECURITY CLASSIFICATION OF: A high

  15. Optically induced effective mass renormalization: the case of graphite image potential states.

    PubMed

    Montagnese, M; Pagliara, S; Galimberti, G; Dal Conte, S; Ferrini, G; van Loosdrecht, P H M; Parmigiani, F

    2016-10-14

    Many-body interactions with the underlying bulk electrons determine the properties of confined electronic states at the surface of a metal. Using momentum resolved nonlinear photoelectron spectroscopy we show that one can tailor these many-body interactions in graphite, leading to a strong renormalization of the dispersion and linewidth of the image potential state. These observations are interpreted in terms of a basic self-energy model, and may be considered as exemplary for optically induced many-body interactions.

  16. Application of the optical method in experimental cardiology: action potential and intracellular calcium concentration measurement.

    PubMed

    Ronzhina, M; Cmiel, V; Janoušek, O; Kolářová, J; Nováková, M; Babula, P; Provazník, I

    2013-01-01

    It has been shown that, in addition to conventional contact electrode techniques, optical methods using fluorescent dyes can be successfully used for cardiac signal measurement. In this review, the physical and technical fundamentals of the method are described, as well as the properties of the most common systems for measuring action potentials and intracellular calcium concentration. Special attention is paid to summarizing limitations and trends in developing this method.

  17. Optical potential approach to the electron-atom impact ionization threshold problem

    NASA Technical Reports Server (NTRS)

    Temkin, A.; Hahn, Y.

    1973-01-01

    The problem of the threshold law for electron-atom impact ionization is reconsidered as an extrapolation of inelastic cross sections through the ionization threshold. The cross sections are evaluated from a distorted wave matrix element, the final state of which describes the scattering from the Nth excited state of the target atom. The actual calculation is carried for the e-H system, and a model is introduced which is shown to preserve the essential properties of the problem while at the same time reducing the dimensionability of the Schrodinger equation. Nevertheless, the scattering equation is still very complex. It is dominated by the optical potential which is expanded in terms of eigen-spectrum of QHQ. It is shown by actual calculation that the lower eigenvalues of this spectrum descend below the relevant inelastic thresholds; it follows rigorously that the optical potential contains repulsive terms. Analytical solutions of the final state wave function are obtained with several approximations of the optical potential.

  18. Dissipative Dynamics of a Bose-Einstein Condensate in an Optical Speckle Potential

    NASA Astrophysics Data System (ADS)

    Kakashvili, Paata; Bhongale, Satyan G.; Pu, Han; Bolech, Carlos J.

    2010-03-01

    Progress in ultra-cold atomic physics allows to engineer and probe analogs of condensed matter systems, which are not plagued by imperfections. In addition, it is also possible to study effects of impurities and disorder, which can be controlled with a great precision. Disorder potential can be imposed by applying an optical-speckle field to a cloud of ultra-cold atoms. The optical speckle is produced by passing a laser beam through a diffusive piece of glass. We propose a theoretical model to understand the hydrodynamic transport of a Bose-Einstein condensate through an optical-speckle potential. Analytic expressions are derived to describe dissipation mechanisms in the limit of weak disorder, such that the depletion of the condensate induced by the speckle potential may be neglected. Comparison of our predictions with the experimental data for large-amplitude dipole oscillations of the condensate shows a striking agreement. Thus, the adequacy of the model in correctly capturing the essential aspects of dissipation in such transport experiments is demonstrated.

  19. Theoretical analysis of motion of a microparticle in an optically created cubic potential

    NASA Astrophysics Data System (ADS)

    Šiler, Martin; Jákl, Petr; Filip, Radim; Ryabov, Artem; Zemánek, Pavel

    2016-12-01

    The noise-to-signal transitions are considered as interesting processes in physics as they might transform environmental noise to useful mechanical effects. Previously, we theoretically analyzed stochastic noise-to-signal transition, first passage times, and other stochastic quantities of overdamped Brownian motion of a nanoparticle in the cubic potential. Here we present a feasibility study showing that the cubic potential can be successfully obtained in a pair of overlapping optical tweezers even in the case of a dielectric microparticle having radius comparable to the trapping wavelength.

  20. Interacting fermionic atoms in optical lattices diffuse symmetrically upwards and downwards in a gravitational potential.

    PubMed

    Mandt, Stephan; Rapp, Akos; Rosch, Achim

    2011-06-24

    We consider a cloud of fermionic atoms in an optical lattice described by a Hubbard model with an additional linear potential. While homogeneous interacting systems mainly show damped Bloch oscillations and heating, a finite cloud behaves differently: It expands symmetrically such that gains of potential energy at the top are compensated by losses at the bottom. Interactions stabilize the necessary heat currents by inducing gradients of the inverse temperature 1/T, with T<0 at the bottom of the cloud. An analytic solution of hydrodynamic equations shows that the width of the cloud increases with t^{1/3} for long times consistent with results from our Boltzmann simulations.

  1. Influence of trapping potentials on the phase diagram of bosonic atoms in optical lattices

    SciTech Connect

    Giampaolo, S.M.; Illuminati, F.; Mazzarella, G.; De Siena, S.

    2004-12-01

    We study the effect of external trapping potentials on the phase diagram of bosonic atoms in optical lattices. We introduce a generalized Bose-Hubbard Hamiltonian that includes the structure of the energy levels of the trapping potential, and show that these levels are in general populated both at finite and zero temperature. We characterize the properties of the superfluid transition for this situation and compare them with those of the standard Bose-Hubbard description. We briefly discuss similar behaviors for fermionic systems.

  2. Development of Optically Active Nanostructures for Potential Applications in Sensing, Therapeutics and Imaging

    NASA Astrophysics Data System (ADS)

    Joshi, Padmanabh

    Materials at nanoscale are finding manifold applications in the various fields like sensing, plasmonics, therapeutics, to mention a few. Large amount of development has taken place regarding synthesis and exploring the novel applications of the various types of nanomaterials like organic, inorganic and hybrid of both. Yet, it is believed that the full potential of different nanomaterials is yet to be fully established stimulating researchers to explore more in the field of nanotechnology. Building on the same premise, in the following studies we have developed the nanomaterials in the class of optically active nanoparticles. First part of the study we have successfully designed, synthesized, and characterized Ag-Fe3O4 nanocomposite substrate for potential applications in quantitative Surface Enhanced Raman Scattering (SERS) measurements. Quantitative SERS-based detection of dopamine was performed successfully. In subsequent study, facile, single-step synthesis of polyethyleneimine (PEI) coated lanthanide based NaYF4 (Yb, Er) nanoparticles was developed and their application as potential photodynamic therapy agent was studied using excitations by light in near infra-red and visible region. In the following and last study, synthesis and characterization of the conjugated polymer nanoparticles was attempted successfully. Functionalization of the conjugated nanoparticles, which is a bottleneck for their potential applications, was successfully performed by encapsulating them in the silica nanoparticles, surface of which was then functionalized by amine group. Three types of optically active nanoparticles were developed for potential applications in sensing, therapeutics and imaging.

  3. Elastic alpha scattering experiments and the alpha-nucleus optical potential at low energies

    SciTech Connect

    Mohr, P.; Kiss, G.G.; Fülöp, Zs.; Galaviz, D.; Gyürky, Gy.; Somorjai, E.

    2013-11-15

    High precision angular distribution data of (α,α) elastic scattering are presented for the nuclei {sup 89}Y, {sup 92}Mo, {sup 106,110,116}Cd, {sup 112,124}Sn, and {sup 144}Sm at energies around the Coulomb barrier. Such data with small experimental uncertainties over the full angular range (20–170°) are the indispensable prerequisite for the extraction of local optical potentials and for the determination of the total reaction cross section σ{sub reac}. A systematic fitting procedure was applied to the experimental scattering data presented to obtain comprehensive local potential parameter sets that are composed of a real folding potential and an imaginary potential of Woods–Saxon surface type. The potential parameters obtained were used in turn to construct a new systematic α-nucleus potential with very few parameters. Although this new potential cannot reproduce the angular distributions with the same small deviations as the local potential, the new potential is able to predict the total reaction cross sections for all cases under study.

  4. The influence of surface potential on the optical switching of spiropyran self assembled monolayers

    NASA Astrophysics Data System (ADS)

    Garling, Tobias; Tong, Yujin; Darwish, Tamim A.; Wolf, Martin; Kramer Campen, R.

    2017-10-01

    Surfaces whose macroscopic properties can be switched by light are potentially useful in a wide variety of applications. One such promising application is electrochemical sensors that can be gated by optically switching the electrode on or off. One way to make such a switchable electrode is by depositing a self-assembled monolayer (SAM) of bistable, optically switchable molecules onto an electrode surface. Quantitative application of any such sensor requires understanding how changes in interfacial field affect the composition of photostationary states, i.e. how does electrode potential affect the extent to which the electrode is on or off when irradiated, and the structure of the SAM. Here we address these questions for a SAM of a 6-nitro-substituted spiro[2H-1-benzopyran-2,2’-indoline] covalently attached through a dithiolane linker to an Au electrode immersed in a 0.1 M solution of Tetramethylammonium hexafluorophosphate in Acetonitrile using interface-specific vibrational spectroscopy. We find that in the absence of irradiation, when the SAM is dominated by the closed spiropyran form, variations in potential of 1 V have little effect on spiropyran relative stability. In contrast, under UV irradiation small changes in potential can have dramatic effects: changes in potential of 0.2 V can completely destabilize the open merocyanine form of the SAM relative to the spiropyran and dramatically change the chromophore orientation. Quantitatively accounting for these effects is necessary to employ this, or any other optically switchable bistable chromophore, in electrochemical applications.

  5. Optical properties of functional composite silver nanoparticles and their potential use in reproductive medicine

    NASA Astrophysics Data System (ADS)

    Syrvatka, Vasyl J.; Slyvchuk, Yurij I.; Rozgoni, Ivan I.; Gevkan, Ivan I.; Bilyy, Oleksandr I.

    2013-06-01

    Silver nanoparticles are promising product of nanotechnology with attractive physicochemical and biological properties. The main aim of the study was to investigate optical properties of functional silver nanoparticles with different composite agents: polyvinylpyrrolidone, bovine serum albumin, hyaluronan and to explore their potential using in reproductive medicine. The date obtained in the study showed that surface modification of nanoparticles leads to change of their optical, physicochemical and biological properties. The optical properties of silver nanoparticles display, that AgNPs with PVP and BSA is most stable in PBS than AgNPs with HA. However the absorption curves after 120 hours of storage show, that AgNPs-HA were the most stable in ethanol. Results show, that silver nanoparticles did not effect on sperm viability and motility, but cause a changes of some biochemical parameters of conditioned medium, particular increase the concentration of triglycerides, activity of alkaline phosphatase, lactate dehydrogenase and decrease the activity of aspartate aminotransferase and alanine aminotransferase after 3 h of in vitro cultivation at 37°C. According to our latest data AgNPs with HA have a less toxic effect on biological processes in rabbits sperm compared with AgNPs with PVP and BSA. Nevertheless all functional composites of silver nanoparticles at the concentration of 0.1 μg/mL have no toxic effect on spermatozoa and can be successfully applied in reproductive medicine at low concentrations as signal enhancers, optical sensors, and biomarkers.

  6. Multifocal fluorescence microscope for fast optical recordings of neuronal action potentials.

    PubMed

    Shtrahman, Matthew; Aharoni, Daniel B; Hardy, Nicholas F; Buonomano, Dean V; Arisaka, Katsushi; Otis, Thomas S

    2015-02-03

    In recent years, optical sensors for tracking neural activity have been developed and offer great utility. However, developing microscopy techniques that have several kHz bandwidth necessary to reliably capture optically reported action potentials (APs) at multiple locations in parallel remains a significant challenge. To our knowledge, we describe a novel microscope optimized to measure spatially distributed optical signals with submillisecond and near diffraction-limit resolution. Our design uses a spatial light modulator to generate patterned illumination to simultaneously excite multiple user-defined targets. A galvanometer driven mirror in the emission path streaks the fluorescence emanating from each excitation point during the camera exposure, using unused camera pixels to capture time varying fluorescence at rates that are ∼1000 times faster than the camera's native frame rate. We demonstrate that this approach is capable of recording Ca(2+) transients resulting from APs in neurons labeled with the Ca(2+) sensor Oregon Green Bapta-1 (OGB-1), and can localize the timing of these events with millisecond resolution. Furthermore, optically reported APs can be detected with the voltage sensitive dye DiO-DPA in multiple locations within a neuron with a signal/noise ratio up to ∼40, resolving delays in arrival time along dendrites. Thus, the microscope provides a powerful tool for photometric measurements of dynamics requiring submillisecond sampling at multiple locations. Copyright © 2015 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  7. Spectroscopy for cold atom gases in periodically modulated optical lattice potential

    NASA Astrophysics Data System (ADS)

    Tokuno, Akiyuki; Giamarchi, Thierry

    2011-03-01

    Cold atoms in optical lattices are vigorously studied experimentally and theoretically as one of the candidates for a quantum simulator. At the same time, further development of probes to microscopic structure of systems is needed. We propose a novel spectroscopy in cold atom experiments by use of periodic phase-modulation of optical lattice potentials. Corresponding to the statistics of atoms, we formulate the different observables: The energy absorption rate for bosonic atom gases, and the doublon production rate for fermionic atom gases. These observables are formulated within the linear response theory. Interestingly they are given by the imaginary part of the retarded current-current correlation function which is familiar as a quantity corresponding to an optical conductivity. As an example, we discuss one-dimensional Mott insulating state, and also compare our spectroscopy with another known spectroscopy by amplitude-modulation of an optical lattice. This work was supported in part by the Swiss SNF under MaNEP and division II.

  8. Multifocal Fluorescence Microscope for Fast Optical Recordings of Neuronal Action Potentials

    PubMed Central

    Shtrahman, Matthew; Aharoni, Daniel B.; Hardy, Nicholas F.; Buonomano, Dean V.; Arisaka, Katsushi; Otis, Thomas S.

    2015-01-01

    In recent years, optical sensors for tracking neural activity have been developed and offer great utility. However, developing microscopy techniques that have several kHz bandwidth necessary to reliably capture optically reported action potentials (APs) at multiple locations in parallel remains a significant challenge. To our knowledge, we describe a novel microscope optimized to measure spatially distributed optical signals with submillisecond and near diffraction-limit resolution. Our design uses a spatial light modulator to generate patterned illumination to simultaneously excite multiple user-defined targets. A galvanometer driven mirror in the emission path streaks the fluorescence emanating from each excitation point during the camera exposure, using unused camera pixels to capture time varying fluorescence at rates that are ∼1000 times faster than the camera’s native frame rate. We demonstrate that this approach is capable of recording Ca2+ transients resulting from APs in neurons labeled with the Ca2+ sensor Oregon Green Bapta-1 (OGB-1), and can localize the timing of these events with millisecond resolution. Furthermore, optically reported APs can be detected with the voltage sensitive dye DiO-DPA in multiple locations within a neuron with a signal/noise ratio up to ∼40, resolving delays in arrival time along dendrites. Thus, the microscope provides a powerful tool for photometric measurements of dynamics requiring submillisecond sampling at multiple locations. PMID:25650920

  9. Characterization of a periodic optical potential by means of particle dynamics analysis in a deterministic regime

    NASA Astrophysics Data System (ADS)

    Arzola, A. V.; Toledo-Cortes, Adriana; Volke-Sepúlveda, Karen; Mateos, Jose L.

    2008-08-01

    We propose a technique for the characterization of a 1D-periodic optical potential by studying the dynamics of non-brownian microscopic particles immerse in water (negligible thermal noise). It has been demonstrated that in the Mie regime, a periodic light pattern applied to a particle acts as an effective potential that depends on the size of the particle respect to the period of the optical landscape [I. Ricardez-Vargas, et.al. Appl. Phys. Lett. 88, 121116 (2006)]. We verify this fact by studying the dynamics of a particle moving within the pattern due to the effect of a known constant external force. The periodic light pattern is generated with interference techniques whereas the external force is applied by means of a controlled inclination of the sample cell. We fit the experimental results for the ensemble average of particle position against time with a theoretical model of the physical situation. In this way we obtain a curve for the optical force as a function of particle's position for different periods.

  10. The role of Magnetic Resonance Imaging and Visual Evoked Potential in management of optic neuritis

    PubMed Central

    Al-Eajailat, Suha Mikail; Al-Madani Senior, Mousa Victor

    2014-01-01

    Introduction To report our experience in management of patients with optic neuritis. The effects of brain magnetic resonance imaging and visual evoked potential on management were investigated Methods This is a four years clinical trial that included patients presenting with first attack of optic neuritis older than 16 years with visual acuity of less than 6/60 and presentation within first week of illness. Brain magnetic resonance imaging and visual evoked potentials were done for all patients. Patients were classified into three groups. First group received placebo, second received oral steroids and third received intravenous and oral steroids. Primary outcome measure was improvement in visual acuity. Results A total number of 150 patients were enrolled in the study. Ocular pain was seen 127 patients Relative afferent pupillary defect in 142 patients and color vision impairment in 131 patients. Abnormal MRI findings were seen in 84 patients. Pattern reversal VEP was abnormal in all patients. Using oral or intravenous steroid resulted in faster recovery but did not affect the final visual outcome. Recurrence rate was higher in patients with multiple MRI lesions and diminished VEP amplitude. Using intravenous steroids decreased recurrence rate in patients with three and more MRI lesions and non recordable VEP response. Conclusion MRI and pattern reversal VEP are recommended to be done in all patients presenting with optic neuritis. We advise to give intravenous methyl prednisolone in patients with multiple MRI white matter lesions and non recordable VEP at presentation. PMID:25018804

  11. Development of global medium-energy nucleon-nucleus optical model potentials

    SciTech Connect

    Madland, D.G.; Sierk, A.J.

    1997-08-01

    The authors report on the development of new global optical model potentials for nucleon-nucleus scattering at medium energies. Using both Schroedinger and Dirac scattering formalisms, the goal is to construct a physically realistic optical potential describing nucleon-nucleus elastic scattering observables for a projectile energy range of (perhaps) 20 meV to (perhaps) 2 GeV and a target mass range of 16 to 209, excluding regions of strong nuclear deformation. They use a phenomenological approach guided by conclusions from recent microscopic studies. The experimental database consists largely of proton-nucleus elastic differential cross sections, analyzing powers, spin-rotation functions, and total reaction cross sections, and neutron-nucleus total cross sections. They will use this database in a nonlinear least-squares adjustment of optical model parameters in both relativistic equivalent Schroedinger (including relativistic kinematics) and Dirac (second-order reduction) formalisms. Isospin will be introduced through the standard Lane model and a relativistic generalization of that model.

  12. Control of a Bose-Einstein condensate on a chip by external optical and magnetic potentials

    SciTech Connect

    Maluckov, A.; Petrovic, J.; Gligoric, G.; Hadzievski, Lj.; Lombardi, P.; Schaefer, F.; Cataliotti, F.S.

    2012-09-15

    In this paper we explore the possibilities of control of a Bose-Einstein condensate on an atom chip by the use of potentials generated by photonic and magnetic components. We show that the fields produced by both types of components can be modelled by a generic exponential potential and derive analytic expressions that allow for an easy assessment of their impact on a trapped condensate. Using dynamical numerical simulations we study the transport of the condensate between the control structures on a chip. We study in detail different regimes of the condensate behaviour in an evanescent light potential generated by a photonic structure in the vicinity of the condensate and in magnetic potentials generated by a wire or a coil. The calculations are based on the reported parameters of atom chip setups and available photonic and magnetic components. Finally, the model is verified by an experiment with a condensate on an atom chip and a coil. - Highlights: Black-Right-Pointing-Pointer Generic potential used to describe both the optical evanescent and magnetic fields. Black-Right-Pointing-Pointer An analytic closed form solution found for the impact of a generic potential on a BEC. Black-Right-Pointing-Pointer BEC dynamics calculated for potential time sequences attainable in experiments. Black-Right-Pointing-Pointer Conditions for BEC transfer by an external field identified. Black-Right-Pointing-Pointer Exponential-potential model validated by a BEC-on-chip experiment.

  13. Influence of different deposition potential on the structural and optical properties of copper selenide nanowires

    NASA Astrophysics Data System (ADS)

    Kaur, Harmanmeet; Kaur, Jaskiran; Singh, Lakhwant

    2016-09-01

    In this paper, nanowires were successfully fabricated from the aqueous solution containing 0.2 M/l CuSO4.5H2O, 0.1 M/l SeO2, 1 g/l PVP and a few drops of H2SO4 in Milli-Q water using electrodeposition technique at room temperature. Influence of different deposition potential on structural and optical properties of copper selenide nanowires has been investigated here. Morphological, structural and optical properties were monitored through field emission scanning electron microscope (FE-SEM), X-ray diffraction (XRD) and UV-visible 1800 spectrophotometer. From the XRD analysis, it was found that the stoichiometric (CuSe) nanowires are formed at deposition potential (-0.6 V) and (+0.6 V). Band gap of nanowires were found to be maximum around 3.13 eV for deposition potential (-0.8 V) and minimum of 2.81 eV for deposition potential (-0.6 V).

  14. Thermally induced passage and current of particles in a highly unstable optical potential

    NASA Astrophysics Data System (ADS)

    Ryabov, Artem; Zemánek, Pavel; Filip, Radim

    2016-10-01

    We discuss the statistics of first-passage times of a Brownian particle moving in a highly unstable nonlinear potential proportional to an odd power of position. We observe temperature-induced shortening of the mean first-passage time and its dependence on the power of nonlinearity. We propose a passage-time fraction as both a simple and experimentally detectable witness of the nonlinearity. It is advantageously independent of all other parameters of the experiment and observable for a small number of trajectories. To better characterize the stochastic passage in the unstable potential, we introduce an analogy of the signal-to-noise ratio for the statistical distribution of the first-passage times. Interestingly, the upper bound for the signal-to-noise ratio is temperature independent in the unstable potential. Finally, we describe the nonequilibrium steady state of the particle cyclically passing through unstable odd nonlinearity. The maximum of the steady-state probability distribution shifts against the directions of the current and this counterintuitive effect increases with temperature. All these thermally induced effects are very promising targets for experimental tests of highly nonlinear stochastic dynamics of particles placed into optical potential landscapes of shaped optical tweezers.

  15. Optical system with potential for remote health monitoring of subsea machinery

    NASA Astrophysics Data System (ADS)

    Jackson, D. A.

    2008-04-01

    A prototype fibre optic sensing system is described with potential to remotely monitor the condition of 3 phase variable frequency sub-sea motors and electric submersible pumps. An indication that the integrity of a powerful electric motor may be compromised can be gained by spectral analysis of the stators drive current, the relative phases of the currents, the measurement of vibration at specific locations on the motor and the temperature of the bearings. The optical interrogation system is based on an imbalanced Mach Zehnder fibre interferometer, illuminated with a broad band source with FBG based current and vibration sensors. Signals from sensors operating at an effective distance of 7 km have been demonstrated.

  16. Gold nanocages: bioconjugation and their potential use as optical imaging contrast agents.

    PubMed

    Chen, Jingyi; Saeki, Fusayo; Wiley, Benjamin J; Cang, Hu; Cobb, Michael J; Li, Zhi-Yuan; Au, Leslie; Zhang, Hui; Kimmey, Michael B; Li, Xingde; Xia, Younan

    2005-03-01

    Gold nanocages of <40 nm in dimension have been synthesized using the galvanic replacement reaction between Ag nanocubes and HAuCl4 in an aqueous solution. By controlling the molar ratio between Ag and HAuCl4, the gold nanocages could be tuned to display surface plasmon resonance peaks around 800 nm, a wavelength commonly used in optical coherence tomography (OCT) imaging. OCT measurements on phantom samples indicate that these gold nanocages have a moderate scattering cross-section of approximately 8.10 x 10(-16) m2 but a very large absorption cross-section of approximately 7.26 x 10(-15) m2, suggesting their potential use as a new class of contrast agents for optical imaging. When bioconjugated with antibodies, the gold nanocages have also been demonstrated for specific targeting of breast cancer cells.

  17. Optical identification of calcium-dependent action potentials transiently expressed in the embryonic rat brainstem.

    PubMed

    Momose-Sato, Y; Sato, K; Kamino, K

    1999-01-01

    Using multiple-site optical recording of transmembrane potential changes, we have found a new type of calcium-dependent action potential expressed transiently in the embryonic rat dorsal motor nucleus of the vagus nerve. Slice preparations with vagus nerve fibers attached were dissected from 12- to 16-day-old embryonic (E12-E16) rat brainstems, and they were stained with a voltage-sensitive merocyanine-rhodanine dye (NK2761). Electrical activities in response to vagal stimuli were optically recorded simultaneously from many sites using 1020- or 128-element photodiode array measuring systems. In brainstem preparations, two types of action potential-related optical signals were identified. One was detected from the dorsolateral region, and was related to sensory nerve activity (Type I). The other was detected from the dorsomedial region, and corresponded to the action potential in the dorsal motor nucleus of the vagus nerve (Type II). We found a difference in the ionic basis of the Type I vs Type II signals. The Type I signal was not altered in Ca2+-free bathing solution and was eliminated by tetrodotoxin, suggesting that the sensory nerve activity is mediated by Na+ currents. The Type II signal at early developmental stages (E12-E13, and some preparations in E14) was also independent of Ca2+. However, the Type II signal in later developmental stages (E15-E16, and some preparations in E14) did depend upon Ca2+: it was eliminated in Ca2+-free Ringer's solution, blocked by Cd2+, Ni2+ or Mn2+, and elicited in Sr2+-containing Ringer's solution, where CaCl2 was replaced with SrCl2. These results suggest that the cation which dominates the motoneuron action potential changes from Na+ to Ca2+ during development, and this change occurs around E14. With pharmacological analysis using Ca2+ channel blockers, we show that the Ca2+ channel mediating the motoneuron action potential is distinct from T-, L-, N-, P- or Q-type channels. Because the vagal action potential in adult

  18. Potential Challenges in Near-Field Scanning Optical Microscopy for Space Applications

    NASA Technical Reports Server (NTRS)

    Vikram, Chandra S.; Witherow, William K.; Rose, M. Franklin (Technical Monitor)

    2000-01-01

    Near-field scanning optical microscopy (NSOM) also called scanning near-field optical microscopy (SNOM) is now well accepted as a powerful tool for sub-wavelength (nanoscale in the optical region) spatial resolution microscopy and a large number of related tasks. The importance lies in the fact of strategic advantages of standard microscopy but with significantly enhanced resolution. Since many modern optical diagnostic techniques have found useful applications in space, it is logical to consider the future role of NSOM in such situations. For example, protein crystal growth study under microgravity conditions is a valid candidate. If applied successfully, processes at molecular level can be studied during the growth. NSOM has already been demonstrated to be useful for the study of such crystals here on earth. The basic principle of NSOM can be illustrated. The illumination-collection mode is shown although several other possible approaches exist. In this, the sample is illuminated and the light from the sample is collected through the same tiny aperture opening. A tapered optical fiber is scanned near the sample surface. The tip is coated generally with a metal with a sub-wavelength aperture opening. The tip-sample distance is maintained constant while scanning. Thus, the optical signal available for collection is generally a function of the optical properties of the sample surface. Since the aperture is sub-wavelength in diameter and the tip is held very close (again in the sub-wavelength domain) to the surface, the lateral resolution in the sub-wavelength domain is obtained. Thus, the typical wavelength- order resolution of ordinary microscopy can be significantly enhanced while maintaining the strategic advantages (no need of sample in vacuum chamber, electron beams, etc). Commercial NSOM systems play a key role in the success and widespread acceptance of the tool. These commercial systems work fairly well in laboratory conditions on earth. However, they may

  19. Potential Challenges in Near-Field Scanning Optical Microscopy for Space Applications

    NASA Technical Reports Server (NTRS)

    Vikram, Chandra S.; Witherow, William K.; Rose, M. Franklin (Technical Monitor)

    2000-01-01

    Near-field scanning optical microscopy (NSOM) also called scanning near-field optical microscopy (SNOM) is now well accepted as a powerful tool for sub-wavelength (nanoscale in the optical region) spatial resolution microscopy and a large number of related tasks. The importance lies in the fact of strategic advantages of standard microscopy but with significantly enhanced resolution. Since many modern optical diagnostic techniques have found useful applications in space, it is logical to consider the future role of NSOM in such situations. For example, protein crystal growth study under microgravity conditions is a valid candidate. If applied successfully, processes at molecular level can be studied during the growth. NSOM has already been demonstrated to be useful for the study of such crystals here on earth. The basic principle of NSOM can be illustrated. The illumination-collection mode is shown although several other possible approaches exist. In this, the sample is illuminated and the light from the sample is collected through the same tiny aperture opening. A tapered optical fiber is scanned near the sample surface. The tip is coated generally with a metal with a sub-wavelength aperture opening. The tip-sample distance is maintained constant while scanning. Thus, the optical signal available for collection is generally a function of the optical properties of the sample surface. Since the aperture is sub-wavelength in diameter and the tip is held very close (again in the sub-wavelength domain) to the surface, the lateral resolution in the sub-wavelength domain is obtained. Thus, the typical wavelength- order resolution of ordinary microscopy can be significantly enhanced while maintaining the strategic advantages (no need of sample in vacuum chamber, electron beams, etc). Commercial NSOM systems play a key role in the success and widespread acceptance of the tool. These commercial systems work fairly well in laboratory conditions on earth. However, they may

  20. Microscopic formulation of medium contributions to the first-order optical potential

    NASA Astrophysics Data System (ADS)

    Chinn, C. R.; Elster, Ch.; Thaler, R. M.

    1993-12-01

    A refinement of the first-order optical potential is introduced, consistent with multiple scattering theory and the spectator expansion. A systematic formalism is presented to treat medium contributions associated with the difference between the effective NN t matrix as required by multiple scattering theory and the free NN t matrix. A mean field potential is used to represent the action of the residual (A-1) nucleus upon the struck target nucleon (medium effects). We calculate elastic proton and neutron scattering from 40Ca, using the full Bonn interaction and two different mean field potentials taken from realistic and proven nuclear structure models. Results indicate that the medium contributions are insignificant at energies above 300 MeV and provide a significant improvement of the theoretical predictions for laboratory energies between 48 and 200 MeV.

  1. Potential-assisted adsorption of bovine serum albumin onto optically transparent carbon electrodes.

    PubMed

    Benavidez, Tomás E; Garcia, Carlos D

    2013-11-19

    This article describes the effect of the applied potential on the adsorption of bovine serum albumin (BSA) to optically transparent carbon electrodes (OTCE). To decouple the effect of the applied potential from the high affinity of the protein for the bare surface, the surface of the OTCE was initially saturated with a layer of BSA. Experiments described in the article show that potential values higher than +500 mV induced a secondary adsorption process (not observed at open-circuit potential), yielding significant changes in the thickness (and adsorbed amount) of the BSA layer obtained. Although the process showed a significant dependence on the experimental conditions selected, the application of higher potentials, selection of pH values around the isoelectric point (IEP) of the protein, high concentrations of protein, and low ionic strengths yielded faster kinetics and the accumulation of larger amounts of protein on the substrate. These experiments, obtained around the IEP of the protein, contrast with the traditional hypothesis that enhanced electrostatic interactions between the polarized substrate and the (oppositely charged) protein are solely responsible for the enhanced adsorption. These results suggest that the potential applied to the electrode is able to polarize the adsorbed layer and induce dipole-dipole interactions between the adsorbed and the incoming protein. This mechanism could be responsible for the potential-dependent oversaturation of the surface and could bolster to the development of surfaces with enhanced catalytic activity and implants with improved biocompatibility.

  2. Effect of coupled channels on the energy dependence of phenomenological optical potential parameters

    NASA Astrophysics Data System (ADS)

    Al-Rayashi, W. S.; Jaghoub, M. I.

    2016-06-01

    The phenomenological optical potential parameters are known to vary with incident energy due to sources of nonlocalities in the nucleon-nucleus elastic scattering process. Here we investigate the effect of one source, which is coupling the ground-state elastic channel to collective inelastic excitations on the energy dependence of the optical potential parameters. For incident energies in the range 10-70 MeV, we considered elastic and inelastic nucleon scattering from light, medium, and heavy nuclei ranging from 6Li to 208Pb. The potential parameters were first determined by fitting the elastic angular distributions only. Then we included coupling to collective excitation channels and determined the potential parameters that reproduced the elastic and inelastic angular distribution data simultaneously. Our results show that coupling to inelastic excitations reduces the energy variations of the potential parameters compared to that of the elastic scattering case. In particular, the our best fit values for the real part of the spin-orbit term are highly stable as a function of energy. The values of the surface imaginary term are not only more stable but are also reduced compared to the elastic case. The reduction is a direct consequence of the channel coupling accounting explicitly for part of the flux removed from the elastic channel. In the fitting process we also searched for the best fit values of the deformation parameters. Our values compare well with the corresponding ones obtained in previous works. Finally, we used our best fit values for the potential and deformation parameters to theoretically predict the total elastic, total cross section, and polarization data. The predicted values are in very good agreement with the experimental data.

  3. A Microscopic Optical Potential Approach to {sup 6,8}He+p Elastic Scattering

    SciTech Connect

    Lukyanov, V. K.; Zemlyanaya, E. V.; Lukyanov, K. V.; Kadrev, D. N.; Antonov, A. N.; Gaidarov, M. K.; Massen, S. E.

    2009-08-26

    A microscopic approach to calculate the optical potential (OP) with the real part obtained by a folding procedure and with the imaginary part inherent in the high-energy approximation (HEA) is applied to study the {sup 6,8}He+p elastic scattering data at energies of tens of MeV/N. The OP's and the cross sections are calculated using different models for the neutron and proton densities of {sup 6,8}He. The role of the spin-orbit (SO) potential and effects of the energy and density dependence of the effective NN forces are studied. Comparison of the calculations with the available experimental data on the elastic scattering differential cross sections at beam energies <100 MeV/N is performed and conclusions on the role of the aforesaid effects are made. It is shown that the present approach, which uses only parameters that renormalize the depths of the OP, can be applied along with other methods like that from the microscopic g-matrix description of the complex proton optical potential.

  4. Calculations of {sup 8}He+p elastic cross sections using a microscopic optical potential

    SciTech Connect

    Lukyanov, V. K.; Zemlyanaya, E. V.; Lukyanov, K. V.; Kadrev, D. N.; Antonov, A. N.; Gaidarov, M. K.; Massen, S. E.

    2009-08-15

    An approach to calculate microscopic optical potential with the real part obtained by a folding procedure and with the imaginary part inherent in the high-energy approximation is applied to study the {sup 8}He+p elastic-scattering data at energies of tens of MeV/nucleon. The neutron and proton density distributions obtained in different models for {sup 8}He are used in the calculations of the differential cross sections. The role of the spin-orbit potential is studied. Comparison of the calculations with the available experimental data on the elastic-scattering differential cross sections at beam energies of 15.7, 26.25, 32, 66, and 73 MeV/nucleon is performed. The problem of the ambiguities of the depths of each component of the optical potential is considered by means of the imposed physical criterion related to the known behavior of the volume integrals as functions of the incident energy. It is shown also that the role of the surface absorption is rather important, in particular for the lowest incident energies (e.g., 15.7 and 26.25 MeV/nucleon)

  5. Optical probing of MgZnO/ZnO heterointerface confinement potential energy levels

    SciTech Connect

    Solovyev, V. V.; Van'kov, A. B.; Kukushkin, I. V.; Falson, J.; Kozuka, Y.; Zhang, D.; Smet, J. H.; Maryenko, D.; Tsukazaki, A.; Kawasaki, M.

    2015-02-23

    Low-temperature photoluminescence and reflectance measurements were employed to study the optical transitions present in two-dimensional electron systems confined at Mg{sub x}Zn{sub 1–x}O/ZnO heterojunctions. Transitions involving A- and B-holes and electrons from the two lowest subbands formed within the confinement potential are detected. In the studied density range of 2.0–6.5 × 10{sup 11 }cm{sup −2}, the inter-subband splitting is measured and the first excited electron subband is shown to be empty of electrons.

  6. Mass dependence of the real optical model potential for light ions

    NASA Astrophysics Data System (ADS)

    Srivastava, D. K.; Ganguly, N. K.; Basu, D. N.

    1983-06-01

    The observed target mass dependence of the volume integral per interacting nucleon pair of the real optical model potential for deuterons, helium-3 and alpha particles is explained in terms of the density dependence of the effective projectile-nucleon interaction. A mass dependence function for light ions is derived, which for density dependent forces consists of a volume, a surface, a curvature, and a higher order correction term. For non-saturating forces, this has only the volume term and fails to account for the observed mass dependence.

  7. Proton-Proton On Shell Optical Potential at High Energies and the Hollowness Effect

    NASA Astrophysics Data System (ADS)

    Arriola, Enrique Ruiz; Broniowski, Wojciech

    2016-07-01

    We analyze the usefulness of the optical potential as suggested by the double spectral Mandelstam representation at very high energies, such as in the proton-proton scattering at ISR and the LHC. Its particular meaning regarding the interpretation of the scattering data up to the maximum available measured energies is discussed. Our analysis reconstructs 3D dynamics from the effective transverse 2D impact parameter representation and suggests that besides the onset of gray nucleons at the LHC there appears an inelasticity depletion (hollowness) which precludes convolution models at the attometer scale.

  8. Cancer imaging by optical coherence tomography: preclinical progress and clinical potential.

    PubMed

    Vakoc, Benjamin J; Fukumura, Dai; Jain, Rakesh K; Bouma, Brett E

    2012-04-05

    The past decade has seen dramatic technological advances in the field of optical coherence tomography (OCT) imaging. These advances have driven commercialization and clinical adoption in ophthalmology, cardiology and gastrointestinal cancer screening. Recently, an array of OCT-based imaging tools that have been developed for preclinical intravital cancer imaging applications has yielded exciting new capabilities to probe and to monitor cancer progression and response in vivo. Here, we review these results, forecast the future of OCT for preclinical cancer imaging and discuss its exciting potential to translate to the clinic as a tool for monitoring cancer therapy.

  9. Linear optical properties of solids within the full-potential linearized augmented planewave method

    NASA Astrophysics Data System (ADS)

    Ambrosch-Draxl, Claudia; Sofo, Jorge O.

    2006-07-01

    We present a scheme for the calculation of linear optical properties by the all-electron full-potential linearized augmented planewave (LAPW) method. A summary of the theoretical background for the derivation of the dielectric tensor within the random-phase approximation is provided. The momentum matrix elements are evaluated in detail for the LAPW basis, and the interband as well as the intra-band contributions to the dielectric tensor are given. As an example the formalism is applied to Aluminum. The program is available as a module within the WIEN2k code.

  10. Optically induced effective mass renormalization: the case of graphite image potential states

    PubMed Central

    Montagnese, M.; Pagliara, S.; Galimberti, G.; Dal Conte, S.; Ferrini, G.; van Loosdrecht, P. H. M.; Parmigiani, F.

    2016-01-01

    Many-body interactions with the underlying bulk electrons determine the properties of confined electronic states at the surface of a metal. Using momentum resolved nonlinear photoelectron spectroscopy we show that one can tailor these many-body interactions in graphite, leading to a strong renormalization of the dispersion and linewidth of the image potential state. These observations are interpreted in terms of a basic self-energy model, and may be considered as exemplary for optically induced many-body interactions. PMID:27739489

  11. Potentials and Limitations of Optical and Radar Satellite Imagery for Grassland Monitoring

    NASA Astrophysics Data System (ADS)

    Buddeberg, Marion; Bach, Heike; Hodrius, Martina; Paulik, Felix; Migdall, Silke; Kuhn, Gisbert

    2016-08-01

    This study served as a starting point to classify converted grassland areas and to determine the ecological value of grasslands. Optical satellite data and SAR data were combined to derive plant parameters and to estimate cutting frequency and cutting dates of grassland sites. Sample points of meadows that had been investigated in the course of the Bavarian grassland monitoring served as ground truth data.The radiative transfer model SLC (Soil-Leaf-Canopy) was used to derive plant parameters such as leaf area and chlorophyll content of the vegetation from optical remote sensing data for the known sample locations. Time series of these plant parameters were used to classify meadows that had potentially been converted into other land use classes. The classification shall assist the Bavarian State Office in adapting future monitoring strategies.Additionally, the analysis of LAI time-series gave an indication of the number of cuts and therefore usage intensity of the investigated samples. The study was completed by observing changes in SAR backscatter values of the investigated sites and comparing the observed patterns to the leaf area time-series of the optical remote sensing data.

  12. Displacement of optical centers in over-the-counter readers: a potential cause of diplopia.

    PubMed

    West, Constance E; Hunter, David G

    2014-06-01

    Induced prism in spectacle lenses, which may result from inadvertent displacement of optical centers, may worsen an existing heterophoria or even cause diplopia, yet over-the-counter reading glasses (OTC readers) are not always assessed by clinicians when evaluating patients with diplopia or asthenopia. To gauge the magnitude of this potential problem, we used a focimeter and prescription aligner to assess the frequency and extent of clinically significant manufacturing variations in a random selection of 160 OTC readers. The optical centers were vertically displaced by ≥3 mm in 11%, with a maximum displacement of 7 mm in 1 pair. Average interpupillary distance was 64 mm (range, 58-74.5 mm), with interpupillary distance outside the normal range of 60-70 mm in 5%. Monocular pupillary distance was asymmetric by ≥5 mm in 4%. A 0.75 D power difference between lenses was measured in one pair of OTC readers. Some OTC readers have misaligned optical centers and other manufacturing defects that are of a magnitude sufficient to exacerbate a heterophoria and cause asthenopia or diplopia.

  13. Coherent Atom Optics with Optical Potentials: A Summary of New Phenomena with Bose-Einstein Condensates at the University of Arizona

    DTIC Science & Technology

    2009-10-08

    Coherent atom optics with optical potentials: a summary of new phenomena with Bose- Einstein Condensates at the University of Arizona Final Project...AZ Abstract The Bose- Einstein condensation (BEC) laboratory at the University of Arizona has built a program of research that focuses on two areas of...universities and experimental work in Arizona progressing in tandem. Project report Among the research goals of the Bose- Einstein condensation lab at

  14. Proton Spectroscopic Factors Deduced from Helium-3 Global Phenomenological and Microscopic Optical Model Potentials

    NASA Astrophysics Data System (ADS)

    Jenny, Lee; Pang, Dan-Yang; Han, Yin-Lu; B. Tsang, M.

    2014-09-01

    Global phenomenological GDP08 and microscopic helium-3 optical model potentials have been recently derived. We evaluate these two potential sets by comparing the elastic scattering data of 25 MeV 3He on 16O, 18O, 19F, 23Na, 24Mg, 25Mg, 26Mg, 27Al, 28Si, 30Si, 31P, 32S, 34S, 35Cl, 37Cl, and 39K isotopes. Using the deuteron angular distributions calculated with the distorted wave Born approximation model, we extract the ground-state proton spectroscopic factors from (3He, d) reactions on the same set of nuclei. The extracted proton spectroscopic factors are compared with the large-basis shell-model calculations.

  15. Dispersive optical potential for nuclei with N and Z values changing toward the nucleon drip lines

    SciTech Connect

    Bespalova, O. V. Romanovsky, E. A.; Spasskaya, T. I.

    2015-01-15

    A method for constructing dispersive optical potentials is proposed for calculating single-particle energies in isotopic chains of spherical and nearly spherical nuclei up to nucleon drip lines. The potential of this method is demonstrated by calculating the neutron and proton single-particle energies in calcium, nickel, and zirconium isotopes. The results agree well with experimental data available for stable isotopes. Predictive calculations of single-particle spectra are performed for isotopes lying far from the beta-stability valley. A comparison of the results with the energies of nucleon separation from nuclei of mass number A and A+1 revealed features of the single-particle spectrum that are characteristic of nuclei containing classical and nonclassical magic numbers of nucleons.

  16. Action Potential Dynamics in Fine Axons Probed with an Axonally Targeted Optical Voltage Sensor.

    PubMed

    Ma, Yihe; Bayguinov, Peter O; Jackson, Meyer B

    2017-01-01

    The complex and malleable conduction properties of axons determine how action potentials propagate through extensive axonal arbors to reach synaptic terminals. The excitability of axonal membranes plays a major role in neural circuit function, but because most axons are too thin for conventional electrical recording, their properties remain largely unexplored. To overcome this obstacle, we used a genetically encoded hybrid voltage sensor (hVOS) harboring an axonal targeting motif. Expressing this probe in transgenic mice enabled us to monitor voltage changes optically in two populations of axons in hippocampal slices, the large axons of dentate granule cells (mossy fibers) in the stratum lucidum of the CA3 region and the much finer axons of hilar mossy cells in the inner molecular layer of the dentate gyrus. Action potentials propagated with distinct velocities in each type of axon. Repetitive firing broadened action potentials in both populations, but at an intermediate frequency the degree of broadening differed. Repetitive firing also attenuated action potential amplitudes in both mossy cell and granule cell axons. These results indicate that the features of use-dependent action potential broadening, and possible failure, observed previously in large nerve terminals also appear in much finer unmyelinated axons. Subtle differences in the frequency dependences could influence the propagation of activity through different pathways to excite different populations of neurons. The axonally targeted hVOS probe used here opens up the diverse repertoire of neuronal processes to detailed biophysical study.

  17. Investigating the photosensitizer-potential of targeted gallium corrole using multimode optical imaging

    NASA Astrophysics Data System (ADS)

    Hwang, Jae Youn; Lubow, Jay; Chu, David; Gross, Zeev; Gray, Harry B.; Farkas, Daniel L.; Medina-Kauwe, Lali K.

    2011-02-01

    We recently developed a novel therapeutic particle, HerGa, for breast cancer treatment and detection. HerGa consists of a tumor-targeted cell penetration protein noncovalently assembled with a gallium-metallated corrole. The corrole is structurally similar to porphyrin, emits intense fluorescence, and has proven highly effective for breast tumor treatment preclinically, without light exposure. Here, we tested HerGa as a photosensitizer for photodynamic therapy and investigated its mechanism of action using multimode optical imaging. Using confocal fluorescence imaging, we observed that HerGa disrupts the mitochondrial membrane potential in situ, and this disruption is substantially augmented by light exposure. In addition, spectral and fluorescence lifetime imaging were utilized to both validate the mitochondrial membrane potential disruption and investigate HerGa internalization, allowing us to optimize the timing for light dosimetry. We observed, using advanced multimode optical imaging, that light at a specific wavelength promotes HerGa cytotoxicity, which is likely to cause disruption of mitochondrial function. Thus, we can identify for the first time the capacity of HerGa as a photosensitizer for photodynamic therapy and reveal its mechanism of action, opening possibilities for therapeutic intervention in human breast cancer management.

  18. Development of a Strontium Magneto-Optical Trap for Probing Casimir-Polder Potentials

    NASA Astrophysics Data System (ADS)

    Martin, Paul J.

    In recent years, cold atoms have been the centerpiece of many remarkably sensitive measurements, and much effort has been made to devise miniaturized quantum sensors and quantum information processing devices. At small distances, however, mechanical effects of the quantum vacuum begin to significantly impact the behavior of the cold-atom systems. A better understanding of how surface composition and geometry affect Casimir and Casimir-Polder potentials would benefit future engineering of small-scale devices. Unfortunately, theoretical solutions are limited and the number of experimental techniques that can accurately detect such short-range forces is relatively small. We believe the exemplary properties of atomic strontium--which have enabled unprecedented frequency metrology in optical lattice clocks--make it an ideal candidate for probing slight spectroscopic perturbations caused by vacuum fluctuations. To that end, we have constructed a magneto-optical trap for strontium to enable future study of atom-surface potentials, and the apparatus and proposed detection scheme are discussed herein. Of special note is a passively stable external-cavity diode laser we developed that is both affordable and competitive with high-end commercial options.

  19. Multifocal visual evoked potential analysis of inflammatory or demyelinating optic neuritis.

    PubMed

    Fraser, Clare L; Klistorner, Alexander; Graham, Stuart L; Garrick, Raymond; Billson, Francis A; Grigg, John R

    2006-02-01

    To determine the sensitivity of multifocal visual evoked potentials (mVEP) in optic neuritis of an inflammatory or demyelinating nature. Cross-sectional study. Sixty-four patients participated who had a confirmed diagnosis of optic neuritis (ON) (past and acute). Based on the McDonald multiple sclerosis (MS) criteria, 25 patients (27 eyes with ON) were deemed to have isolated optic neuritis and thus not have MS (i.e., the not-MS group), and 19 patients (24 eyes with ON) had a diagnosis of MS (i.e., the MS group). The remaining 20 patients (25 eyes with ON) were at a high risk of MS, but diagnostic evaluation was equivocal, and thus were classified as the possible MS group. A control group of 20 normal patients was enrolled. The mVEP test was performed using the Accumap. All ON patients had recent magnetic resonance imaging scans of the brain and spinal cord. Multifocal visual evoked potentials amplitude and latency values were analyzed within each group and were compared with the normal controls. No abnormality was recorded on mVEP in the control group. Of all the ON eyes, 74 (97.3%) were abnormal on mVEP testing. Amplitude values were abnormal in 92.6% of not-MS eyes, 92.0% of possible MS eyes, and 100% of those with MS, and latency was abnormal in 33.3%, 76.0%, and 100%, respectively. There was a significant difference in the mVEP latency z-scores among all ON groups (P<0.01; Kruskal-Wallis test). Although distribution graphs of latency z-scores in the not-MS and MS groups had single peaks and were clearly separate from each other, the latency z-score distribution within the possible MS group in postacute patients was bimodal, with each peak corresponding to the distribution of the not-MS and MS group, respectively. The mVEP latency z-scores had a sensitivity and specificity of 100% in detecting patients with ON due to MS when compared with normal patients. The mVEP test is a sensitive and specific tool for detecting optic neuritis. There was a significant

  20. Developmental impairment of compound action potential in the optic nerve of myelin mutant taiep rats.

    PubMed

    Roncagliolo, Manuel; Schlageter, Carol; León, Claudia; Couve, Eduardo; Bonansco, Christian; Eguibar, José R

    2006-01-05

    The taiep rat is a myelin mutant with an initial hypomyelination, followed by a progressive demyelination of the CNS. The neurological correlates start with tremor, followed by ataxia, immobility episodes, epilepsy and paralysis. The optic nerve, an easily-isolable central tract fully myelinated by oligodendrocytes, is a suitable preparation to evaluate the developmental impairment of central myelin. We examined the ontogenic development of optic nerve compound action potentials (CAP) throughout the first 6 months of life of control and taiep rats. Control optic nerves (ON) develop CAPs characterized by three waves. Along the first month, the CAPs of taiep rats showed a delayed maturation, with lower amplitudes and longer latencies than controls; at P30, the conduction velocity has only a third of the normal value. Later, as demyelination proceeds, the conduction velocity of taiep ONs begins to decrease and CAPs undergo a gradual temporal dispersion. CAPs of control and taiep showed differences in their pharmacological sensitivity to TEA and 4-AP, two voltage dependent K+ channel-blockers. As compared with TEA, 4-AP induced a significant increase of the amplitudes and a remarkable broadening of CAPs. After P20, unlike controls, the greater sensitivity to 4-AP exhibited by taiep ONs correlates with the detachment and retraction of paranodal loops suggesting that potassium conductances could regulate the excitability as demyelination of CNS axons progresses. It is concluded that the taiep rat, a long-lived mutant, provides a useful model to study the consequences of partial demyelination and the mechanisms by which glial cells regulate the molecular organization and excitability of axonal membranes during development and disease.

  1. Diquat derivatives: highly active, two-dimensional nonlinear optical chromophores with potential redox switchability.

    PubMed

    Coe, Benjamin J; Fielden, John; Foxon, Simon P; Harris, James A; Helliwell, Madeleine; Brunschwig, Bruce S; Asselberghs, Inge; Clays, Koen; Garín, Javier; Orduna, Jesús

    2010-08-04

    In this article, we present a detailed study of structure-activity relationships in diquaternized 2,2'-bipyridyl (diquat) derivatives. Sixteen new chromophores have been synthesized, with variations in the amino electron donor substituents, pi-conjugated bridge, and alkyl diquaternizing unit. Our aim is to combine very large, two-dimensional (2D) quadratic nonlinear optical (NLO) responses with reversible redox chemistry. The chromophores have been characterized as their PF(6)(-) salts by using various techniques including electronic absorption spectroscopy and cyclic voltammetry. Their visible absorption spectra are dominated by intense pi --> pi* intramolecular charge-transfer (ICT) bands, and all show two reversible diquat-based reductions. First hyperpolarizabilities beta have been measured by using hyper-Rayleigh scattering with an 800 nm laser, and Stark spectroscopy of the ICT bands affords estimated static first hyperpolarizabilities beta(0). The directly and indirectly derived beta values are large and increase with the extent of pi-conjugation and electron donor strength. Extending the quaternizing alkyl linkage always increases the ICT energy and decreases the E(1/2) values for diquat reduction, but a compensating increase in the ICT intensity prevents significant decreases in Stark-based beta(0) responses. Nine single-crystal X-ray structures have also been obtained. Time-dependent density functional theory clarifies the molecular electronic/optical properties, and finite field calculations agree with polarized HRS data in that the NLO responses of the disubstituted species are dominated by 'off-diagonal' beta(zyy) components. The most significant findings of these studies are: (i) beta(0) values as much as 6 times that of the chromophore in the technologically important material (E)-4'-(dimethylamino)-N-methyl-4-stilbazolium tosylate; (ii) reversible electrochemistry that offers potential for redox-switching of optical properties over multiple states

  2. Dissolved Organic Carbon and Optical Properties as Indicators of Trihalomethane Formation Potential in an Agricultural Watershed

    NASA Astrophysics Data System (ADS)

    Pellerin, B. A.; Bergamaschi, B. A.; Spencer, R. G.

    2006-12-01

    Elevated concentrations of dissolved organic carbon (DOC) in the Sacramento-San Joaquin Delta waters may result in the formation of high levels of carcinogenic disinfection byproducts such as trihalomethane during drinking water treatment. The importance of Central Valley agricultural lands as sources of DOC and THM- precursors upstream of the Delta is presently unknown. We are quantifying contributions of DOC and THM- precursors from the Willow Slough watershed, a 425 km2 agriculturally-dominated catchment. During 2006, water samples were collected weekly at the mouth of the watershed and analyzed for DOC concentrations, optical properties (UV absorbance and fluorescence), and trihalomethane formation potential (THMFP). Additional synoptic samples were collected seasonally (winter, spring, summer) from 16 watershed locations and analyzed for optical properties, DOC concentrations, and THMFP. DOC concentrations generally ranged from approximately 2 to 4 mg/L at the watershed outlet during winter and spring, but increased weekly to 8 mg/L following the onset of irrigation. The THMFP at the mouth of the water was correlated with DOC concentration (r2 = 0.87), with higher concentrations during high discharge events and lower concentrations during summer and prolonged rain-free periods. In addition, the species of THM varied between high and low-flow periods, with THM formation dominated by brominated species during low- flow periods and chlorinated species during rainfall-runoff events. Optical characterization of DOC via UV absorbance and fluorescence suggests changes in DOC composition between high- and low-flow periods, likely reflective of changing sources and flowpaths of runoff.

  3. Measured daylighting potential of a static optical louver system under real sun and sky conditions

    DOE PAGES

    Konis, Kyle; Lee, Eleanor S.

    2015-05-04

    Side-by-side comparisons were made over solstice-to-solstice changes in sun and sky conditions between an optical louver system (OLS) and a conventional Venetian blind set at a horizontal slat angle and located inboard of a south-facing, small-area, clerestory window in a full-scale office testbed. Daylight autonomy (DA), window luminance, and ceiling luminance uniformity were used to assess performance. The performance of both systems was found to have significant seasonal variation, where performance under clear sky conditions improved as maximum solar altitude angles transitioned from solstice to equinox. Although the OLS produced fewer hours per day of DA on average than themore » Venetian blind, the OLS never exceeded the designated 2000 cd/m2 threshold for window glare. In contrast, the Venetian blind was found to exceed the visual discomfort threshold over a large fraction of the day during equinox conditions. Notably, these peak periods of visual discomfort occurred during the best periods of daylighting performance. Luminance uniformity was analyzed using calibrated high dynamic range luminance images. Under clear sky conditions, the OLS was found to increase the luminance of the ceiling as well as produce a more uniform distribution. Furthermore, compared to conventional venetian blinds, the static optical sunlight redirecting system studied has the potential to significantly reduce the annual electrical lighting energy demand of a daylit space and improve the quality from the perspective of building occupants by consistently transmitting useful daylight while eliminating window glare.« less

  4. Measured daylighting potential of a static optical louver system under real sun and sky conditions

    SciTech Connect

    Konis, Kyle; Lee, Eleanor S.

    2015-05-04

    Side-by-side comparisons were made over solstice-to-solstice changes in sun and sky conditions between an optical louver system (OLS) and a conventional Venetian blind set at a horizontal slat angle and located inboard of a south-facing, small-area, clerestory window in a full-scale office testbed. Daylight autonomy (DA), window luminance, and ceiling luminance uniformity were used to assess performance. The performance of both systems was found to have significant seasonal variation, where performance under clear sky conditions improved as maximum solar altitude angles transitioned from solstice to equinox. Although the OLS produced fewer hours per day of DA on average than the Venetian blind, the OLS never exceeded the designated 2000 cd/m2 threshold for window glare. In contrast, the Venetian blind was found to exceed the visual discomfort threshold over a large fraction of the day during equinox conditions. Notably, these peak periods of visual discomfort occurred during the best periods of daylighting performance. Luminance uniformity was analyzed using calibrated high dynamic range luminance images. Under clear sky conditions, the OLS was found to increase the luminance of the ceiling as well as produce a more uniform distribution. Furthermore, compared to conventional venetian blinds, the static optical sunlight redirecting system studied has the potential to significantly reduce the annual electrical lighting energy demand of a daylit space and improve the quality from the perspective of building occupants by consistently transmitting useful daylight while eliminating window glare.

  5. Optical magnetic detection of single-neuron action potentials using quantum defects in diamond

    PubMed Central

    Barry, John F.; Turner, Matthew J.; Schloss, Jennifer M.; Glenn, David R.; Song, Yuyu; Lukin, Mikhail D.; Park, Hongkun; Walsworth, Ronald L.

    2016-01-01

    Magnetic fields from neuronal action potentials (APs) pass largely unperturbed through biological tissue, allowing magnetic measurements of AP dynamics to be performed extracellularly or even outside intact organisms. To date, however, magnetic techniques for sensing neuronal activity have either operated at the macroscale with coarse spatial and/or temporal resolution—e.g., magnetic resonance imaging methods and magnetoencephalography—or been restricted to biophysics studies of excised neurons probed with cryogenic or bulky detectors that do not provide single-neuron spatial resolution and are not scalable to functional networks or intact organisms. Here, we show that AP magnetic sensing can be realized with both single-neuron sensitivity and intact organism applicability using optically probed nitrogen-vacancy (NV) quantum defects in diamond, operated under ambient conditions and with the NV diamond sensor in close proximity (∼10 µm) to the biological sample. We demonstrate this method for excised single neurons from marine worm and squid, and then exterior to intact, optically opaque marine worms for extended periods and with no observed adverse effect on the animal. NV diamond magnetometry is noninvasive and label-free and does not cause photodamage. The method provides precise measurement of AP waveforms from individual neurons, as well as magnetic field correlates of the AP conduction velocity, and directly determines the AP propagation direction through the inherent sensitivity of NVs to the associated AP magnetic field vector. PMID:27911765

  6. An optical system with potential for remote health monitoring of subsea machinery

    NASA Astrophysics Data System (ADS)

    Jackson, D. A.

    2009-03-01

    A prototype fibre-optic sensing system is described with potential to remotely monitor the condition of three-phase variable frequency subsea motors and electric submersible pumps. An indication that the integrity of a powerful electric motor may be compromised can be gained by spectral analysis of the stator drive current, the phases of the currents, the measurement of vibration at specific locations on the motor and the temperature of the bearings. The optical interrogation system is based on an imbalanced Mach-Zehnder fibre interferometer, illuminated with a broadband source with fibre Bragg gratings (FBGs) used as the basic transducers for the current and vibration measurements. Signals were recovered at a distance of 7 km, for the 'in house' current sensor at an effective ac current of 500 A at frequencies from 10 to 1000 Hz with a S/N ratio of 45 dB, together with the relative phases between the currents. These signals were generated with a simulated high power three-phase electric motor. A commercial accelerometer was incorporated into the system which demonstrated a sensitivity of 1 mg Hz-1/2 also from 10 to 1000 Hz. As the interrogation system can only be used to detect dynamic signals, a second interrogation for quasi-static temperature measurements is required; although this was not deployed, possible applications other than bearing temperature measurement are considered.

  7. Optical isomer separation of potential analgesic drug candidates by using capillary electrophoresis.

    PubMed

    Ferrara, G; Santagati, N A; Aturki, Z; Fanali, S

    1999-09-01

    Using cyclodextrin capillary zone electrophoresis (CD-CZE), baseline separation of synthetic potential analgesic drug diastereoisomer candidates 6,11-dimethyl-1,2,3,4,5,6-hexahydro-3-[(2'-methoxycarbonyl-2'-phenylc yclopropyl)methyl]-2,6-methano-3-benzazocin-8-ol (MPCB) and 6,11-dimethyl-1,2,3,4,5,6-hexahydro-3-[[2'-methoxycarbonyl-2'(4-chloroph enyl)cyclopropyl]methyl]-2,6-methano-3-benzazocin-8-ol (CCB) was achieved. Among the cyclodextrins tested (hydroxypropyl-, carboxymethyl- and sulfobutyl-beta-cyclodextrin (HP-beta-CD, CM-beta-CD and SBE-beta-CD)) SBE-beta-CD was found to be the most effective complexing agent, allowing good optical isomer separation. Resolution was also influenced by the CD concentration, pH of the buffer and presence of organic modifier in the background electrolyte. The optimum experimental conditions for the separation of studied analgesic drugs were found using 25 mM borate buffer at pH 9 containing 40 mM of SBE-beta-CD and 20% v/v of methanol. Using the above-mentioned background electrolyte, it was also possible to separate, in the same run, the enantiomers of normetazocine (NMZ) as well as the optical isomers of (+/-)-cis-2-chloromethyl-1-phenyl cyclopropancarboxylic acid methyl ester (PCE) or (+/-)-cis-2-chloromethyl-1-(4-chlorophenyl)cyclopropancarboxylic acid methyl ester (CPCE) reagents used in the synthesis of the studied analgesic drugs).

  8. Optical magnetic detection of single-neuron action potentials using quantum defects in diamond.

    PubMed

    Barry, John F; Turner, Matthew J; Schloss, Jennifer M; Glenn, David R; Song, Yuyu; Lukin, Mikhail D; Park, Hongkun; Walsworth, Ronald L

    2016-12-06

    Magnetic fields from neuronal action potentials (APs) pass largely unperturbed through biological tissue, allowing magnetic measurements of AP dynamics to be performed extracellularly or even outside intact organisms. To date, however, magnetic techniques for sensing neuronal activity have either operated at the macroscale with coarse spatial and/or temporal resolution-e.g., magnetic resonance imaging methods and magnetoencephalography-or been restricted to biophysics studies of excised neurons probed with cryogenic or bulky detectors that do not provide single-neuron spatial resolution and are not scalable to functional networks or intact organisms. Here, we show that AP magnetic sensing can be realized with both single-neuron sensitivity and intact organism applicability using optically probed nitrogen-vacancy (NV) quantum defects in diamond, operated under ambient conditions and with the NV diamond sensor in close proximity (∼10 µm) to the biological sample. We demonstrate this method for excised single neurons from marine worm and squid, and then exterior to intact, optically opaque marine worms for extended periods and with no observed adverse effect on the animal. NV diamond magnetometry is noninvasive and label-free and does not cause photodamage. The method provides precise measurement of AP waveforms from individual neurons, as well as magnetic field correlates of the AP conduction velocity, and directly determines the AP propagation direction through the inherent sensitivity of NVs to the associated AP magnetic field vector.

  9. Evoked membrane potential change in rat optic nerve fiber: computer simulation.

    PubMed

    Cazenave-Loustalet, Vincent; Qiao, Qing-Li; Li, Li-Ming; Ren, Qiu-Shi

    2007-11-01

    The optic nerve is a key component regarding research on visual prosthesis. Previous pharmacological and electrical studies has pinned down the main features of the mechanisms underlying the nerve impulse in the rat optic nerve, and this work proposed a mathematical model to simulate these phenomena. The main active nodal channels: fast Na+, persistent Na+, slow K+ and a fast repolarizing K+ (A-current) were added on a double layer representation of the axon. A simplified representation of K+ accumulation and clearance in the vicinity of the Ranvier node was integrated in this model. The model was able to generate the following features. In the presence of 4-aminopyridine (4-AP), spike duration increased and a depolarizing afterpotential (DAP) appeared. In the presence of 4-AP and tetraethylammonium (TEA), the DAP was followed by a hyperpolarizing afterpotential (AHP) and the amplitude of this AHP increased with the frequency of the stimulation. In normal conditions (no drugs): DAP and AHP were absent after a single action potential (AP) and a short train of AP; there was a relative refractoriness in amplitude lasting for 30 ms after an AP; an early AHP was revealed by a continuous depolarizing current; and there was a partial spike adaptation for a long current step stimulus. The model successfully reproduced previous experiments results including long-lasting stimulation experiment, which is known to modify nerve physiological parameter values and is a key issue for visual prosthesis research.

  10. Evaluation of the Potential Optical Radiation Hazards with Led Lamps Intended for Home Use.

    PubMed

    James, Robert H; Landry, Robert J; Walker, Bennett N; Ilev, Ilko K

    2017-01-01

    The authors evaluated the potential for ocular damage from optical radiation emitted by Light Emitting Diode (LED) based lamps used for general illumination. Ten LED lamps were randomly selected off the shelf from a local home improvement store. The LEDs were behind diffusers in half of these lamps, while in the other half, the LEDs were clearly visible. In addition, a battery powered LED lantern having a LED source behind a diffuser was measured. The optical radiation emissions from two common incandescent lamps were also measured to compare the relative hazards of LED and incandescent lamps. All lamp samples were evaluated in accordance with procedures specified in the American National Standards Institute/Illuminating Engineering Society of North America (ANSI/IESNA) Standard RP-27.3. For comparison purposes, the lantern and 100 W incandescent lamps were also evaluated according to ANSI RP-27.1. These measurements indicate that no lamp evaluated poses any photobiological hazard, and therefore, all lamps fall in the RP-27.3 category of Exempt Group. However, when evaluated in accordance with RP-27.1, the 100 W incandescent lamp would be classified in Risk Group 1 (low risk), while the LED lantern would be classified in Risk Group 2 (moderate risk).

  11. Evaluating the therapeutic potential of idebenone and related quinone analogues in Leber hereditary optic neuropathy.

    PubMed

    Yu-Wai-Man, Patrick; Soiferman, Devorah; Moore, David G; Burté, Florence; Saada, Ann

    2017-09-01

    Leber hereditary optic neuropathy (LHON) is an important cause of mitochondrial blindness among young adults. In this study, we investigated the potential of four quinone analogues (CoQ1, CoQ10, decylubiquinone and idebenone) in compensating for the deleterious effect of the m.11778G>A mitochondrial DNA mutation. The LHON fibroblast cell lines tested exhibited reduced cell growth, impaired mitochondrial bioenergetics and elevated levels of reactive oxygen species (ROS). Idebenone increased ATP production and reduced ROS levels, but the effect was partial and cell-specific. The remaining quinone analogues had variable effects and a negative impact on certain mitochondrial parameters was observed in some cell lines. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

  12. Effective dynamics of cold atoms flowing in two ring-shaped optical potentials with tunable tunneling

    NASA Astrophysics Data System (ADS)

    Aghamalyan, Davit; Amico, Luigi; Kwek, L. C.

    2013-12-01

    We study the current dynamics of coupled atomic condensates flowing in two ring-shaped optical potentials. We provide a specific setup where the ring-ring coupling can be tuned in an experimentally feasible way. It is demonstrated that the imaginary time effective action of the system in a weak coupling regime provides a two-level-system dynamics for the phase slip across the two rings. Through two-mode Gross- Pitaevskii mean-field equations, the real-time dynamics of the population imbalance and the phase difference between the two condensates is thoroughly analyzed analytically, as a function of the relevant physical parameters of the system. In particular, we find that the macroscopic quantum self-trapping phenomenon is induced in the system if the flowing currents assume a nonvanishing difference.

  13. Energy-Dependent microscopic optical potential for p+{sup 9}Be elastic scattering

    SciTech Connect

    Maridi, H. M.; Farag, M. Y. H. Esmael, E. H.

    2016-06-10

    The p+{sup 9}Be elastic scattering at an energy range up to 200 MeV/nucleon is analyzed using the single-folding model. The density- and isospin-dependent M3Y-Paris nucleon-nucleon (NN) interaction is used for the real part and the NN-scattering amplitude of the high-energy approximation for the imaginary one. The analysis reveals that the cross-section data are reproduced well at energies up to 100 MeV/nucleon by use of the partial-wave expansion. For higher energies, the eikonal approximation give results better than the partial-wave expansion calculations. The volume integrals of the optical-potential parts have systematic energy dependencies, and they are parameterized in empirical formulas.

  14. The microscopic (optical and SEM) examination of putrefaction fluid deposits (PFD). Potential interest in forensic anthropology.

    PubMed

    Charlier, P; Georges, P; Bouchet, F; Huynh-Charlier, I; Carlier, R; Mazel, V; Richardin, P; Brun, L; Blondiaux, J; Lorin de la Grandmaison, G

    2008-10-01

    This article describes the potential interest in physical and forensic anthropology of the microscopic analysis of residues of putrefaction fluid, a calcified deposit frequently found associated with bone rests. Its sampling and analysis seem straightforward and relatively reproducible. Samples came from archeological material (Monterenzio Vecchia, an Etruscan necropolis from the north of Italy dated between the fifth and third century B.C.; body rests of Agnès Sorel, royal mistress died in 1450 A.D.; skull and grave of French King Louis the XI and Charlotte of Savoy dated from 1483 A.D.). All samples were studied by direct optical microscope and scanning electron microscopy. Many cytological, histological, and elemental analysis were possible, producing precious data for the identification of these remains and, in some cases, the cause of death.

  15. Impact of the α optical model potential on the γ-process nucleosynthesis

    NASA Astrophysics Data System (ADS)

    Simon, A.; Beard, M.; Meyer, B. S.; Roach, B.

    2017-06-01

    γ-process nucleosynthesis that occurs during an explosion of a type II supernova can be modeled via post-processing network calculations that require a model of the stellar environment and the rates for all the nuclear reactions involved in the process. The nuclear input for these calculations relies on reaction rates obtained from statistical models. In this work, the sensitivity of the γ-process nucleosynthesis to the α optical model potential used in statistical model was investigated. Network calculations were performed for two sets of reaction rates, the current version of Reaclib and with rates for α-induced reactions and their inverse replaced with those calculated using Talys. Significant changes in the final abundance pattern were observed and a list of reactions that need to be measured in order to discriminate between the two nucleosynthesis scenarios is provided.

  16. Uncertainties of α-particle optical potential assessment around and below the Coulomb barrier

    NASA Astrophysics Data System (ADS)

    Avrigeanu, V.; Avrigeanu, M.; Mǎnǎilescu, C.

    2017-06-01

    A competition of the low-energy Coulomb excitation (CE) with the compound nucleus (CN) formation in α-induced reactions below the Coulomb barrier has recently been assumed in order to make possible the description of the latter as well as the α-particle emission by the same optical model (OM) potential. However, we show in the present work that the corresponding partial waves and integration radii provide evidence for the distinct account of the CE cross section and OM total-reaction cross section σR. Thus the largest contribution to CE cross section comes by far from partial waves larger than the ones contributing to the σR values. Finally, effects of statistical model parameters are comparatively discussed.

  17. Light valve based on nonimaging optics with potential application in cold climate greenhouses

    NASA Astrophysics Data System (ADS)

    Valerio, Angel A.; Mossman, Michele A.; Whitehead, Lorne A.

    2014-09-01

    We have evaluated a new concept for a variable light valve and thermal insulation system based on nonimaging optics. The system incorporates compound parabolic concentrators and can readily be switched between an open highly light transmissive state and a closed highly thermally insulating state. This variable light valve makes the transition between high thermal insulation and efficient light transmittance practical and may be useful in plant growth environments to provide both adequate sunlight illumination and thermal insulation as needed. We have measured light transmittance values exceeding 80% for the light valve design and achieved thermal insulation values substantially exceeding those of traditional energy efficient windows. The light valve system presented in this paper represents a potential solution for greenhouse food production in locations where greenhouses are not feasible economically due to high heating cost.

  18. The rising demand for energy: a potential for optical fiber sensors in the monitoring sector

    NASA Astrophysics Data System (ADS)

    Bosselmann, Thomas; Willsch, Michael; Ecke, Wolfgang

    2008-03-01

    For a long time electric power was taken as a natural unlimited resource. With globalization the demand for energy has risen. This has brought rising prices for fossil fuels, as well as a diversification of power generation. Besides conventional fossil, nuclear plants are coming up again. Renewable energy sources are gaining importance resulting in recent boom of wind energy plants. In the past reliability and availability and an extremely long lifetime were of paramount importance. Today this has been added by cost, due to the global competition and the high fuel costs. New designs of power components have increased efficiency using lesser material. Higher efficiency causes inevitably higher stress on the materials, of which the machines are built. As a reduction of lifetime is not acceptable and maintenance costs are expected to be at a minimum, condition monitoring systems are going to being used now. This offers potentials for fiber optic sensor applications.

  19. Serial visual evoked potentials in 90 untreated patients with acute optic neuritis.

    PubMed

    Frederiksen, J L; Petrera, J

    1999-10-01

    To establish the value of visual evoked potentials (VEPs) for monitoring disease evolution, we undertook a population-based study of 90 untreated patients 12 to 57 years of age (median, 32 years) at the onset of optic neuritis (ON) and after 2, 4, 12, and 52 weeks. Optic neuritis was monosymptomatic (AMON) in 58 patients and part of the clinically definite multiple sclerosis (CDMS) in 32 patients. The VEP was abnormal in eyes with acute ON in 69 (77%) of 90 patients at onset and in 80 (89%) of 90 patients at one or more of the follow-up sessions. In eyes with acute ON, normalization of an initially abnormal VEP was observed during 1-year follow-up in 13 (19%) of 69 patients. At onset of ON, VEP was abnormal in 35% of the clinically unaffected eyes. By parametric analysis of variance, the latencies (P = 0.0058), the amplitudes (P = 0.0298), and the combined VEP scores (P = 0.0345) in the eyes with acute ON were significantly associated with the time after onset. The latencies were influenced by the presence of CDMS (P = 0.0033), whereas the amplitudes were influenced by visual acuity (P = 0.0000). When visual acuity was included in a multifactor model, the time after onset was, however, not significantly associated with the amplitude (P = 0.8826). The mean latency of the VEPs in eyes with acute ON was significantly shorter in AMON than in ON as part of CDMS. This study provides evidence that VEP abnormality is often transitory, and that VEP often normalizes during follow-up. The diagnostic yield is increased by repeating VEP in the spontaneous course of acute ON. Visual evoked potential is a sensitive tool for revealing subclinical lesions.

  20. Separable Representation of Nucleon-Nucleus Optical Potentials as Input to (d; p) Reaction Calculations

    NASA Astrophysics Data System (ADS)

    Hlophe, Linda D.

    The three-body description of deuteron-induced nuclear reactions requires the nucleon-nucleon (NN) and effective nucleon-nucleus interactions as input. The latter are given by Optical Model Potentials (OMPs), which are complex as well as energy-dependent. While a lot of effort has been dedicated to creating separable NN potentials, the same is not true for the nucleon-nucleus OMPs. In this work, separable representations of nucleon-nucleus OMPs are presented. To construct separable representations of neutron-nucleus OMPs, a scheme due to Ernst, Shakin, and Thaler (EST) is adopted as a starting point. It is shown that, by including both incoming and outgoing scattering states in the EST scheme, separable expansions for complex neutron-nucleus potentials that partially obey reciprocity are obtained. For the application to neutron-nucleus potentials that are complex as well as energy-dependent, a further generalization is carried out leading to an energy-dependent separable expansion that exactly fulfills reciprocity. By working exclusively with half-shell transition matrices in momentum space, the implementation of these separable representation schemes is straightforward. The proton-nucleus interaction consists of a short-ranged nuclear piece as well as the long-ranged point-Coulomb potential. After separating the point-Coulomb piece via the Gell-Mann-Goldberger relation, one is left with the short-ranged potential in the Coulomb basis. An extension of the separable representation schemes for neutron-nucleus OMPs to proton-nucleus systems thus requires scattering solutions in the Coulomb basis. This complicates a momentum space implementation of the aforementioned separable expansions. However, by employing the techniques first suggested by Elster, Liu, and Thaler, the separable representation schemes generalized for proton-nucleus OMPs are implemented in a similar manner to neutron-nucleus OMPs. Taking into account the internal structure of the nucleus leads to

  1. Momentum dependence of the imaginary part of the ω- and η^'-nucleus optical potential

    NASA Astrophysics Data System (ADS)

    Friedrich, S.; Nanova, M.; Metag, V.; Afzal, F. N.; Bayadilov, D.; Bantes, B.; Beck, R.; Becker, M.; Böse, S.; Brinkmann, K.-T.; Crede, V.; Drexler, P.; Eberhardt, H.; Elsner, D.; Frommberger, F.; Funke, Ch.; Gottschall, M.; Grüner, M.; Gutz, E.; Hammann, Ch.; Hannappel, J.; Hartmann, J.; Hillert, W.; Hoffmeister, Ph.; Honisch, Ch.; Jude, T.; Kaiser, D.; Kalischewski, F.; Keshelashvili, I.; Klein, F.; Koop, K.; Krusche, B.; Lang, M.; Makonyi, K.; Messi, F.; Müller, J.; Müllers, J.; Piontek, D.-M.; Rostomyan, T.; Schaab, D.; Schmidt, Ch.; Schmieden, H.; Schmitz, R.; Seifen, T.; Sokhoyan, V.; Sowa, C.; Spieker, K.; Thiel, A.; Thoma, U.; Triffterer, T.; Urban, M.; van Pee, H.; Walther, D.; Wendel, Ch.; Werthmüller, D.; Wiedner, U.; Wilson, A.; Witthauer, L.; Wunderlich, Y.; Zaunick, H.-G.

    2016-09-01

    The photoproduction of ω and η^' mesons off carbon and niobium nuclei has been measured as a function of the meson momentum for incident photon energies of 1.2-2.9GeV at the electron accelerator ELSA. The mesons have been identified via the ω → π0 γ → 3 γ and η^' → π0 π0η → 6 γ decays, respectively, registered with the CBELSA/TAPS detector system. From the measured meson momentum distributions the momentum dependence of the transparency ratio has been determined for both mesons. Within a Glauber analysis the in-medium ω and η^' widths and the corresponding absorption cross sections have been deduced as a function of the meson momentum. The results are compared to recent theoretical predictions for the in-medium ω width and η^'-N absorption cross sections. The energy dependence of the imaginary part of the ω- and η^'-nucleus optical potential has been extracted. The finer binning of the present data compared to the existing data allows a more reliable extrapolation towards the production threshold. The modulus of the imaginary part of the η^'-nucleus potential is found to be about three times smaller than recently determined values of the real part of the η^'-nucleus potential, which makes the η^' meson a suitable candidate for the search for meson-nucleus bound states. For the ω meson, the modulus of the imaginary part near threshold is comparable to the modulus of the real part of the potential. As a consequence, only broad structures can be expected, which makes the observation of ω mesic states very difficult experimentally.

  2. Optical model potential of A =3 projectiles for 1 p -shell nuclei

    NASA Astrophysics Data System (ADS)

    Pang, D. Y.; Dean, W. M.; Mukhamedzhanov, A. M.

    2015-02-01

    A set of global optical potential parameters describing the A =3 particles (3He and 3H ) elastic scattering from 1 p -shell nuclei, HT 1 p , is obtained by simultaneously fitting 118 sets of experimental data of 3He and 3H elastic scattering from 9Be,10B ,11B ,12C ,13C ,14C ,14N ,15N ,16O ,17O , and 18O with incident energies from 4 ≤E ≤118.5 MeV and 24 sets of elastic scattering data with the 6Li and 7Li targets from 3 ≤E ≤44 MeV. HT 1 p is found to be superior to GDP08 [D. Y. Pang, P. Roussel-Chomaz, H. Savajols, R. L. Varner, and R. Wolski, Phys. Rev. C 79, 024615 (2009), 10.1103/PhysRevC.79.024615], which is a systematic potential designed for the heavy-target region, in the reproduction of the angular distributions of elastic scattering cross sections of 3He and 3H from 1 p -shell nuclei at energies below 100 MeV. At energies above 100 MeV, GDP08 is found to be better than HT1p.

  3. Neutron scattering from elemental indium, the optical model, and the bound-state potential

    SciTech Connect

    Chiba, S. ); Guenther, P.T.; Lawson, R.D.; Smith, A.B. )

    1990-06-01

    Neutron differential elastic-scattering cross sections of elemental indium are measured from 4.5 to 10 MeV at incident-energy intervals of {approx}500 keV. Seventy or more differential values are obtained at each incident energy, distributed between {approx}18{degree} and 160{degree}. These experimental results are combined with lower-energy values previously obtained at this laboratory, and with 11 and 14 MeV results in the literature, to form a comprehensive elastic-scattering database extending from {approx}1.5 to 14 MeV. These data are interpreted in terms of a conventional spherical optical model. The resulting potential is extrapolated to the bound-state regime. It is shown that in the middle of the 50--82 neutron shell, the potential derived from the scattering results adequately describes the binding energies of article states, but does not do well for hole states. The latter shortcoming is attributed to the holes states having occupational probabilities sufficiently different from unity, so that the exclusion principle become a factor, and to the rearrangement of the neutron core. 68 refs.

  4. Review of Techniques to Achieve Optical Surface Cleanliness and Their Potential Application to Surgical Endoscopes

    PubMed Central

    Kreeft, Davey; Arkenbout, Ewout Aart; Henselmans, Paulus Wilhelmus Johannes; van Furth, Wouter R.; Breedveld, Paul

    2017-01-01

    A clear visualization of the operative field is of critical importance in endoscopic surgery. During surgery the endoscope lens can get fouled by body fluids (eg, blood), ground substance, rinsing fluid, bone dust, or smoke plumes, resulting in visual impairment. As a result, surgeons spend part of the procedure on intermittent cleaning of the endoscope lens. Current cleaning methods that rely on manual wiping or a lens irrigation system are still far from ideal, leading to longer procedure times, dirtying of the surgical site, and reduced visual acuity, potentially reducing patient safety. With the goal of finding a solution to these issues, a literature review was conducted to identify and categorize existing techniques capable of achieving optically clean surfaces, and to show which techniques can potentially be implemented in surgical practice. The review found that the most promising method for achieving surface cleanliness consists of a hybrid solution, namely, that of a hydrophilic or hydrophobic coating on the endoscope lens and the use of the existing lens irrigation system. PMID:28511635

  5. Hysteresis of Current in Noninteracting Atomic Fermi Gases in Optical Ring Potentials

    NASA Astrophysics Data System (ADS)

    Metcalf, Mekena; Chien, Chih-Chun; Lai, Chen-Yen

    Hysteresis is a ubiquitous phenomenon, which can be found in magnets, superfluids, and other many-body systems. Although interactions are present in most systems exhibiting hysteresis, here we show the current of a non-interacting Fermi gas in an optical ring potential produces hysteresis behavior when driven by a time-dependent artificial gauge field and subject to dissipation. Fermions in a ring potential threaded with flux can exhibit a persistent current when the system is in thermal equilibrium, but cold-atoms are clean and dissipation for reaching thermal equilibrium may be introduced by an external, thermal bath. We use the standard relaxation approximation to model the dynamics of cold-atoms driven periodically by an artificial gauge field. A competition of the driven time and the relaxation time leads to hysteresis of the mass current, and work done on the system, as a function of the relaxation time, exhibits similar behavior as Kramers transition rate in chemical reaction and one-dimensional thermal transport.

  6. [Comparison of the Aulhorn flicker test with visual evoked potentials in the diagnosis of optic neuritis].

    PubMed

    Trauzettel-Klosinski, S; Diener, H C; Fahle, M

    1990-01-01

    The Aulhorn flicker test and visual evoked cortical potentials (VEP) are of great value for the diagnosis of optic neuritis (ON). In the present study, the two methods were compared for the first time within the same group of patients. The study comprised 405 eyes (175 suffering from active or subsided ON). The results were evaluated with a double-blind procedure. With the flicker test, the subjective brightness of flickering light is determined as a function of the flicker frequency. This test gives pathological results only in active ON and normalizes when the active phase is over. The test can discriminate between active and subsided ON as well as between the recurrent and chronic courses of the disease. Differentiation is not possible with the VEP, since the VEP latencies are prolonged even after the end of the active period of the disease. The sensitivity of the flicker test was 84.4%. The sensitivity of the VEP was 72.7% for our group of patients suffering from ON if the criterion of increased latency was used alone. In the diagnosis of multiple sclerosis (MS), the proportion of correctly identified pathological VEP results is increased because of the detection of demyelination of the optic nerve that causes no clinical symptoms. The specificity of the flicker test was 97.8% and that of the VEP 86.5%. If both methods were combined, the sensitivity was 98.4% and specificity 99.6%. The two methods obviously have different characteristics and seem to rely upon different demyelination effects. Each method has its advantages and disadvantages as well as optimal indications.(ABSTRACT TRUNCATED AT 250 WORDS)

  7. Fast optical measurement of membrane potential changes at multiple sites on an individual nerve cell.

    PubMed

    Zecević, D; Antić, S

    1998-03-01

    In the past 15 years, there has been renewed interest in the detailed spatial analyses of signalling in individual neurons. The behaviour of many nerve cells is difficult to understand on the basis of microelectrode measurements from the soma. Regional electrical properties of neurons have been studied using sharp microelectrode and patch-electrode recordings from neuronal processes, high-resolution multisite optical recordings of Ca2+ concentration changes and by using models to predict the distribution of membrane potential in the entire neuronal arborization. Additional, direct evidence about electrical signalling in neuronal processes of individual cells in situ can now be obtained by recording of membrane potential changes using voltage-sensitive dyes. A number of recent studies have shown that active regional electrical properties of individual neurons are extraordinarily complex, dynamic and, in the general case, impossible to predict by present models. This places a great significance on measuring capabilities in experiments studying the detailed functional organization of individual neurons. The main difficulty in obtaining a more accurate description was that experimental techniques for studying regional electrical properties of neurons were not available. With this motivation, we worked on the development of multisite voltage-sensitive dye recording as a potentially powerful approach. The results described here demonstrate that the sensitivity of voltage-sensitive dye recording from branches of individual neurons was brought to a level at which it can be used routinely in physiologically relevant experiments. The crucial figure-of-merit in this approach, the signal-to-noise ratio from neuronal processes in intact ganglia, has been improved by a factor of roughly 150 over previously available signals. The improvement in the sensitivity allowed, for the first time, direct investigation of several important aspects of the functional organization of an

  8. Overlapping double potential wells in a single optical microtube cavity with vernier-scale-like tuning effect

    NASA Astrophysics Data System (ADS)

    Madani, A.; Bolaños Quiñones, V. A.; Ma, L. B.; Miao, S. D.; Jorgensen, M. R.; Schmidt, O. G.

    2016-04-01

    Spatially and temporally overlapping double potential wells are realized in a hybrid optical microtube cavity due to the coexistence of an aggregate of luminescent quantum dots embedded in the tube wall and the cone-shaped tube's geometry. The double potential wells produce two independent sets of optical modes with different sets of mode numbers, indicating phase velocity separation for the modes overlapping at the same frequency. The overlapping mode position can be tuned by modifying the tube cavity, where these mode sets shift with different magnitudes, allowing for a vernier-scale-like tuning effect.

  9. Overlapping double potential wells in a single optical microtube cavity with vernier-scale-like tuning effect

    SciTech Connect

    Madani, A.; Schmidt, O. G.; Bolaños Quiñones, V. A.; Ma, L. B. Jorgensen, M. R.; Miao, S. D.

    2016-04-25

    Spatially and temporally overlapping double potential wells are realized in a hybrid optical microtube cavity due to the coexistence of an aggregate of luminescent quantum dots embedded in the tube wall and the cone-shaped tube's geometry. The double potential wells produce two independent sets of optical modes with different sets of mode numbers, indicating phase velocity separation for the modes overlapping at the same frequency. The overlapping mode position can be tuned by modifying the tube cavity, where these mode sets shift with different magnitudes, allowing for a vernier-scale-like tuning effect.

  10. Modeling the action-potential-sensitive nonlinear-optical response of myelinated nerve fibers and short-term memory

    NASA Astrophysics Data System (ADS)

    Shneider, M. N.; Voronin, A. A.; Zheltikov, A. M.

    2011-11-01

    The Goldman-Albus treatment of the action-potential dynamics is combined with a phenomenological description of molecular hyperpolarizabilities into a closed-form model of the action-potential-sensitive second-harmonic response of myelinated nerve fibers with nodes of Ranvier. This response is shown to be sensitive to nerve demyelination, thus enabling an optical diagnosis of various demyelinating diseases, including multiple sclerosis. The model is applied to examine the nonlinear-optical response of a three-neuron reverberating circuit—the basic element of short-term memory.

  11. Study of the nucleon radiative captures 8Li(n,γ)9Li, 9Be(p,γ)10B, 10Be(n,γ)11Be, 10B(p,γ)11C, and 16O(p,γ)17F at thermal and astrophysical energies

    NASA Astrophysics Data System (ADS)

    Dubovichenko, Sergey; Dzhazairov-Kakhramanov, Albert

    We have studied the neutron-capture reactions 8Li(n,γ)9Li and its role in the primordial nucleosynthesis. The n +8Li →9Li + γ reaction has a significant astrophysical interest because it includes one of the variants of chain of primordial nucleosynthesis processes of the Universe and thermonuclear reactions in type II supernovae. Furthermore, we consider the 9Be(p,γ)10B reaction in the astrophysical energy range in the modified potential cluster model (MPCM) with splitting of orbital states according to Young tableaux and, in some cases, with forbidden states (FS). The reaction 9Be(p,γ)10B plays an important role in primordial and stellar nucleosynthesis of light elements in the p shell. Hydrogen burning in second-generation stars occurs via the proton-proton (pp) chain and CNO cycle, with the 9Be(p,γ)10B reaction serving as an intermediate link between these cycles. Furthermore, the possibility of describing available experimental data for the total reaction cross-sections of neutron radiative capture on 10Be at thermal and astrophysical energies has been shown. This reaction is a part of one of the variants of the chain of primordial nucleosynthesis of the Universe due to which the elements with a mass of A > 11-12 may be formed. The results in the field of study of thermonuclear proton-capture reaction on 10B at ultralow, i.e., astrophysical energies will be presented further. The possibility of description of the experimental data for the astrophysical S-factor of the proton radiative capture on 16O to the ground state (GS) of 17F was considered in the frame of the MPCM with FS and classification of the states according to Young tableaux. It was shown that on the basis of the E1 transitions from the states of p16O scattering to the GS of 17F in the p16O channel generally succeed to explain the value of measured cross-sections at astrophysical energies.

  12. Spectral-Domain Optical Coherence Tomography as a Potential Biomarker in Huntington's Disease.

    PubMed

    Andrade, Carlos; Beato, João; Monteiro, Ana; Costa, Andreia; Penas, Susana; Guimarães, Joana; Reis, Fernando Falcão; Garrett, Carolina

    2016-03-01

    Spectral-domain optical coherence tomography has been used in several neurological conditions, and peripapillary and macular measurements have been proposed as potential biomarkers in these disorders. The aim of this study was to investigate retinal and choroidal changes in Huntington's disease and to evaluate any potential correlation with the stage of the disease. A cross-sectional observational study compared patients with Huntington's disease and controls. Patients were evaluated using the Unified Huntington's Disease Rating Scale. Spectral-domain optical coherence tomography with enhanced depth imaging was used, and peripapillary choroidal and retinal nerve fiber layer thickness and macular retinal and choroidal thickness were evaluated. Fifteen eyes of 8 patients and 16 eyes of 8 sex-, age-, and mean refractive error-matched healthy controls were included. Average (231.3 ± 52.8 vs 296.2 ± 57.1, P = 0.033), central (341.8 ± 70.5 vs 252.0 ± 57.9, P = 0.015), and inferior (225.3 ± 57.9 vs 313.8 ± 55.2, P = 0.007) macular choroidal thickness were significantly reduced in patients, in comparison with controls. No differences were observed in macular retina or peripapillary retinal and choroidal measurements. However, there was a negative correlation between Total Motor Score of the Unified Huntington's Disease Rating Scale and average (r(2)  = 0.585, P = 0.027), superior (r(2)  = 0.653, P = 0.015), nasal (r(2)  = 0.642, P = 0.017), and inferior (r(2)  = 0.574, P = 0.029) macular retinal thickness. Our results suggest that both the choroidal and retinal macula are altered in Huntington's disease and may become useful biomarkers for monitoring neurodegeneration in this disease. The involvement of the choroid may also support the recent findings of vascular involvement in Huntington's disease. © 2016 International Parkinson and Movement Disorder Society.

  13. Contrasting optical properties of surface waters across the Fram Strait and its potential biological implications

    NASA Astrophysics Data System (ADS)

    Pavlov, Alexey K.; Granskog, Mats A.; Stedmon, Colin A.; Ivanov, Boris V.; Hudson, Stephen R.; Falk-Petersen, Stig

    2015-03-01

    Underwater light regime is controlled by distribution and optical properties of colored dissolved organic matter (CDOM) and particulate matter. The Fram Strait is a region where two contrasting water masses are found. Polar water in the East Greenland Current (EGC) and Atlantic water in the West Spitsbergen Current (WSC) differ with regards to temperature, salinity and optical properties. We present data on absorption properties of CDOM and particles across the Fram Strait (along 79° N), comparing Polar and Atlantic surface waters in September 2009 and 2010. CDOM absorption of Polar water in the EGC was significantly higher (more than 3-fold) compared to Atlantic water in the WSC, with values of absorption coefficient, aCDOM(350), m- 1 of 0.565 ± 0.100 (in 2009) and 0.458 ± 0.117 (in 2010), and 0.138 ± 0.036 (in 2009) and 0.153 ± 0.039 (in 2010), respectively. An opposite pattern was observed for particle absorption with higher absorption found in the eastern part of the Fram Strait. Average values of particle absorption (aP(440), m- 1) were 0.016 ± 0.013 (in 2009) and 0.014 ± 0.011 (in 2010), and 0.047 ± 0.012 (in 2009) and 0.016 ± 0.014 (in 2010), respectively for Polar and Atlantic water. Thus absorption of light in eastern part of the Fram Strait is dominated by particles - predominantly phytoplankton, and the absorption of light in the western part of the strait is dominated by CDOM, with predominantly terrigenous origin. As a result the balance between the importance of CDOM and particulates to the total absorption budget in the upper 0-10 m shifts across Fram Strait. Under water spectral irradiance profiles were generated using ECOLIGHT 5.4.1 and the results indicate that the shift in composition between dissolved and particulate material does not influence substantially the penetration of photosynthetic active radiation (PAR, 400-700 nm), but does result in notable differences in ultraviolet (UV) light penetration, with higher attenuation in the

  14. 7D-folding integral in a density-dependent microscopic optical model potential for nucleon-nucleus scattering

    SciTech Connect

    Arellano, H. F.

    2011-09-15

    Microscopic optical model potentials, based on density-dependent effective interactions, involve multidimensional integrals to account for the full Fermi motion of the target struck nucleon throughout the nucleus. If a spherical matter distribution is assumed, then each matrix element of the optical potential requires the evaluation of seven-dimensional integrals. In this work we provide a full account of these integrals, retaining the genuine off-shell structure of the nucleon-nucleon effective interaction. The evaluation is based on the asymptotic separation of the optical model potential for nucleon-nucleus scattering in momentum space, where the potential is split into a free t-matrix contribution and another which depends exclusively on the gradient of the density-dependent g matrix. The calculated potentials, based on the Paris nucleon-nucleon (NN) potential, are applied to proton elastic scattering from {sup 16}O and {sup 90}Zr at beam energies between 30 and 65 MeV. The results were compared with two approximations to the unabridged expression, revealing moderate differences among their scattering observables. When comparing with results based on the Argonne v{sub 18} NNpotential, these differences appear smaller than those attainable by the choice of the internucleon potential.

  15. Fiber optic probe enabled by surface-enhanced Raman scattering for early diagnosis of potential acute rejection of kidney transplant

    NASA Astrophysics Data System (ADS)

    Chi, Jingmao; Chen, Hui; Tolias, Peter; Du, Henry

    2014-06-01

    We have explored the use of a fiber-optic probe with surface-enhanced Raman scattering (SERS) sensing modality for early, noninvasive and, rapid diagnosis of potential renal acute rejection (AR) and other renal graft dysfunction of kidney transplant patients. Multimode silica optical fiber immobilized with colloidal Ag nanoparticles at the distal end was used for SERS measurements of as-collected urine samples at 632.8 nm excitation wavelength. All patients with abnormal renal graft function (3 AR episodes and 2 graft failure episodes) who were clinically diagnosed independently show common unique SERS spectral features in the urines collected just one day after transplant. SERS-based fiber-optic probe has excellent potential to be a bedside tool for early diagnosis of kidney transplant patients for timely medical intervention of patients at high risk of transplant dysfunction.

  16. Towards an optical potential for rare-earths through coupled channels

    SciTech Connect

    Nobre, G. P. A.; Herman, M.; Palumbo, A.; Hoblit, S.; Brown, D.; Dietrich, F. S.

    2014-11-11

    The coupled-channel theory is a natural way of treating nonelastic channels, in particular those arising from collective excitations, defined by nuclear deformations. Proper treatment of such excitations is often essential to the accurate description of reaction experimental data. Previous works have applied different models to specific nuclei with the purpose of determining angular-integrated cross sections. In this work, we present an extensive study of the effects of collective couplings and nuclear deformations on integrated cross sections as well as on angular distributions in a consistent manner for neutron-induced reactions on nuclei in the rare-earth region. This specific subset of the nuclide chart was chosen precisely because of a clear static deformation pattern. We analyze the convergence of the coupled-channel calculations regarding the number of states being explicitly coupled. Inspired by the work done by Dietrich et al., a model for deforming the spherical Koning-Delaroche optical potential as function of quadrupole and hexadecupole deformations is also proposed. We demonstrate that the obtained results of calculations for total, elastic and inelastic cross sections, as well as elastic and inelastic angular distributions correspond to a remarkably good agreement with experimental data for scattering energies above around a few MeV.

  17. High-Resolution Optical Coherence Tomography Retinal Imaging: A Case Series Illustrating Potential and Limitations

    PubMed Central

    Puzyeyeva, Olena; Lam, Wai Ching; Flanagan, John G.; Brent, Michael H.; Devenyi, Robert G.; Mandelcorn, Mark S.; Wong, Tien; Hudson, Christopher

    2011-01-01

    Purpose. To present a series of retinal disease cases that were imaged by spectral domain optical coherence tomography (SD-OCT) in order to illustrate the potential and limitations of this new imaging modality. Methods. The series comprised four selected cases (one case each) of age-related macular degeneration (ARMD), diabetic retinopathy (DR), central retinal artery occlusion (CRAO), and branch retinal vein occlusion (BRVO). Patients were imaged using the Heidelberg Spectralis (Heidelberg Engineering, Germany) in SD-OCT mode. Patients also underwent digital fundus photography and clinical assessment. Results. SD-OCT imaging of a case of age-related macular degeneration revealed a subfoveal choroidal neovascular membrane with detachment of the retinal pigment epithelium (RPE) and neurosensory retina. Using SD-OCT, the cases of DR and BRVO both exhibited macular edema with cystoid spaces visible in the outer retina. Conclusions. The ability of SD-OCT to clearly and objectively elucidate subtle morphological changes within the retinal layers provides information that can be used to formulate diagnoses with greater confidence. PMID:21969910

  18. Complex topological structures of frustrated liquid crystals with potential for optics and photonics (Presentation Recording)

    NASA Astrophysics Data System (ADS)

    Žumer, Slobodan; Čančula, Miha; Čopar, Simon; Ravnik, Miha

    2015-10-01

    Geometrical constrains and intrinsic chirality in nematic mesophases enable formation of stable and metastable complex defect structures. Recently selected knotted and linked disclinations have been formed using laser manipulation of nematic braids entangling colloidal particles in nematic colloids [Tkalec et al., Science 2011; Copar et al., PNAS 2015]. In unwinded chiral nematic phases stable and metastable toron and hopfion defects have been implemented by laser tweezers [Smalyukh et al., Nature Materials 2010; Chen et al., PRL2013] and in chiral nematic colloids particles dressed by solitonic deformations [Porenta et al., Sci. Rep. 2014]. Modelling studies based on the numerical minimisation of the phenomenological free energy, supported with the adapted topological theory [Copar and Zumer, PRL 2011; Copar, Phys. Rep. 2014] allow describing the observed nematic defect structures and also predicting numerous structures in confined blue phases [Fukuda and Zumer, Nature Comms 2011 and PRL 2011] and stable knotted disclinations in cholesteric droplets with homeotropic boundary [Sec et al., Nature Comms 2014]. Coupling the modeling with finite difference time domain light field computation enables understanding of light propagation and light induced restructuring in these mesophases. The method was recently demonstrated for the description of low intensity light beam changes during the propagation along disclination lines [Brasselet et al., PRL 2009; Cancula et al., PRE 2014]. Allowing also high intensity light an order restructuring is induced [Porenta et al., Soft Matter 2012; Cancula et al., 2015]. These approaches help to uncover the potential of topological structures for beyond-display optical and photonic applications.

  19. Potential of electric quadrupole transitions in radium isotopes for single-ion optical frequency standards

    SciTech Connect

    Versolato, O. O.; Wansbeek, L. W.; Jungmann, K.; Timmermans, R. G. E.; Willmann, L.; Wilschut, H. W.

    2011-04-15

    We explore the potential of the electric quadrupole transitions 7s {sup 2}S{sub 1/2}-6d {sup 2}D{sub 3/2}, 6d {sup 2}D{sub 5/2} in radium isotopes as single-ion optical frequency standards. The frequency shifts of the clock transitions due to external fields and the corresponding uncertainties are calculated. Several competitive {sup A}Ra{sup +} candidates, with A= 223-229, are identified. In particular, we show that the transition 7s {sup 2}S{sub 1/2} (F=2,m{sub F}=0)-6d {sup 2}D{sub 3/2} (F=0,m{sub F}=0) at 828 nm in {sup 223}Ra{sup +}, with no linear Zeeman and electric quadrupole shifts, stands out as a relatively simple case, which could be exploited as a compact, robust, and low-cost atomic clock operating at a fractional frequency uncertainty of 10{sup -17}. With more experimental effort, the {sup 223,225,226}Ra{sup +} clocks could be pushed to a projected performance reaching the 10{sup -18} level.

  20. Imaging of normal and pathologic joint synovium using nonlinear optical microscopy as a potential diagnostic tool

    NASA Astrophysics Data System (ADS)

    Tiwari, Nivedan; Chabra, Sanjay; Mehdi, Sheherbano; Sweet, Paula; Krasieva, Tatiana B.; Pool, Roy; Andrews, Brian; Peavy, George M.

    2010-09-01

    An estimated 1.3 million people in the United States suffer from rheumatoid arthritis (RA). RA causes profound changes in the synovial membrane of joints, and without early diagnosis and intervention, progresses to permanent alterations in joint structure and function. The purpose of this study is to determine if nonlinear optical microscopy (NLOM) can utilize the natural intrinsic fluorescence properties of tissue to generate images that would allow visualization of the structural and cellular composition of fresh, unfixed normal and pathologic synovial tissue. NLOM is performed on rabbit knee joint synovial samples using 730- and 800-nm excitation wavelengths. Less than 30 mW of excitation power delivered with a 40×, 0.8-NA water immersion objective is sufficient for the visualization of synovial structures to a maximum depth of 70 μm without tissue damage. NLOM imaging of normal and pathologic synovial tissue reveals the cellular structure, synoviocytes, adipocytes, collagen, vascular structures, and differential characteristics of inflammatory infiltrates without requiring tissue processing or staining. Further study to evaluate the ability of NLOM to assess the characteristics of pathologic synovial tissue and its potential role for the management of disease is warranted.

  1. Experimental confirmation of potential swept source optical coherence tomography performance limitations

    PubMed Central

    Zheng, Kathy; Liu, Bin; Huang, Chuanyong; Brezinski, Mark E.

    2009-01-01

    Optical coherence tomography (OCT) has demonstrated considerable potential for a wide range of medical applications. Initial work was done in the time domain OCT (TD-OCT) approach, but recent interest has been generated with spectral domain OCT (SD-OCT) approaches. While SD-OCT offers higher data acquisition rates and no movable parts, we recently pointed out theoretical inferior aspects to its performance relative to TD-OCT. In this paper we focus on specific limitations of swept source OCT (SS-OCT), as this is the more versatile of the two SD-OCT embodiments. We present experimental evidence of reduced imaging penetration, increased low frequency noise, higher multiple scattering (which can be worsened still via aliasing), increased need to control the distance from the sample, and saturation of central bandwidth frequencies. We conclude that for scenarios where the dynamic range is relatively low (e.g., retina), the distance from the sample is relatively constant, or high acquisition rates are needed, SS-OCT has a role. However, when penetration remains important in the setting of a relatively high dynamic range, acquisition rates above video rate are not needed, or the distance to the tissue is not constant, TD-OCT may be the superior approach. PMID:19023378

  2. Characterization of novel microsphere chain fiber optic tips for potential use in ophthalmic laser surgery

    NASA Astrophysics Data System (ADS)

    Hutchens, Thomas C.; Darafsheh, Arash; Fardad, Amir; Antoszyk, Andrew N.; Ying, Howard S.; Astratov, Vasily N.; Fried, Nathaniel M.

    2012-06-01

    Ophthalmic surgery may benefit from use of more precise fiber delivery systems during laser surgery. Some current ophthalmic surgical techniques rely on tedious mechanical dissection of tissue layers. In this study, chains of sapphire microspheres integrated into a hollow waveguide distal tip are used for erbium:YAG laser ablation studies in contact mode with ophthalmic tissues, ex vivo. The laser's short optical penetration depth combined with the small spot diameters achieved with this fiber probe may provide more precise tissue removal. One-, three-, and five-microsphere chain structures were characterized, resulting in FWHM diameters of 67, 32, and 30 μm in air, respectively, with beam profiles comparable to simulations. Single Er:YAG pulses of 0.1 mJ and 75-μs duration produced ablation craters with average diameters of 44, 30, and 17 μm and depths of 26, 10, and 8 μm, for one-, three-, and five-sphere structures, respectively. Microsphere chains produced spatial filtering of the multimode Er:YAG laser beam and fiber, providing spot diameters not otherwise available with conventional fiber systems. Because of the extremely shallow treatment depth, compact focused beam, and contact mode operation, this probe may have potential for use in dissecting epiretinal membranes and other ophthalmic tissues without damaging adjacent retinal tissue.

  3. Characterization of novel microsphere chain fiber optic tips for potential use in ophthalmic laser surgery

    PubMed Central

    Hutchens, Thomas C.; Darafsheh, Arash; Fardad, Amir; Antoszyk, Andrew N.; Ying, Howard S.; Astratov, Vasily N.

    2012-01-01

    Abstract. Ophthalmic surgery may benefit from use of more precise fiber delivery systems during laser surgery. Some current ophthalmic surgical techniques rely on tedious mechanical dissection of tissue layers. In this study, chains of sapphire microspheres integrated into a hollow waveguide distal tip are used for erbium:YAG laser ablation studies in contact mode with ophthalmic tissues, ex vivo. The laser’s short optical penetration depth combined with the small spot diameters achieved with this fiber probe may provide more precise tissue removal. One-, three-, and five-microsphere chain structures were characterized, resulting in FWHM diameters of 67, 32, and 30 μm in air, respectively, with beam profiles comparable to simulations. Single Er:YAG pulses of 0.1 mJ and 75-μs duration produced ablation craters with average diameters of 44, 30, and 17 μm and depths of 26, 10, and 8 μm, for one-, three-, and five-sphere structures, respectively. Microsphere chains produced spatial filtering of the multimode Er:YAG laser beam and fiber, providing spot diameters not otherwise available with conventional fiber systems. Because of the extremely shallow treatment depth, compact focused beam, and contact mode operation, this probe may have potential for use in dissecting epiretinal membranes and other ophthalmic tissues without damaging adjacent retinal tissue. PMID:22734790

  4. Characterization of novel microsphere chain fiber optic tips for potential use in ophthalmic laser surgery.

    PubMed

    Hutchens, Thomas C; Darafsheh, Arash; Fardad, Amir; Antoszyk, Andrew N; Ying, Howard S; Astratov, Vasily N; Fried, Nathaniel M

    2012-06-01

    Ophthalmic surgery may benefit from use of more precise fiber delivery systems during laser surgery. Some current ophthalmic surgical techniques rely on tedious mechanical dissection of tissue layers. In this study, chains of sapphire microspheres integrated into a hollow waveguide distal tip are used for erbium:YAG laser ablation studies in contact mode with ophthalmic tissues, ex vivo. The laser's short optical penetration depth combined with the small spot diameters achieved with this fiber probe may provide more precise tissue removal. One-, three-, and five-microsphere chain structures were characterized, resulting in FWHM diameters of 67, 32, and 30 μm in air, respectively, with beam profiles comparable to simulations. Single Er:YAG pulses of 0.1 mJ and 75-μs duration produced ablation craters with average diameters of 44, 30, and 17 μm and depths of 26, 10, and 8 μm, for one-, three-, and five-sphere structures, respectively. Microsphere chains produced spatial filtering of the multimode Er:YAG laser beam and fiber, providing spot diameters not otherwise available with conventional fiber systems. Because of the extremely shallow treatment depth, compact focused beam, and contact mode operation, this probe may have potential for use in dissecting epiretinal membranes and other ophthalmic tissues without damaging adjacent retinal tissue.

  5. Ocean optical data from potential OTEC sites in the Gulf of Mexico. Technical memo

    SciTech Connect

    Bushnell, M.; Maul, G.A.

    1982-03-01

    Prior to being able to make statements about OTEC modification of the ocean, the natural variability has to be known. Natural variability in the ocean's optical properties can be interpreted in part as natural variation of the biological activity. One of the more promising means of monitoring the bio-optical variability is through the use of satellite colorimeters such as the Coastal Zone Color Scanner on NIMBUS-7. The optical instruments used, the vessels involved, and the data available are detailed.

  6. Some methods for determining the limit of potential image quality of optical systems of various complexities using the database

    NASA Astrophysics Data System (ADS)

    Bezdidko, S.

    2016-09-01

    In the article some methods for processing the information contained in a database are offered with the purpose of extraction of the knowledge, the experience and the intuition of the designers, coded in the database. It gives much attention to the methods for determinating limit potential image quality of optical systems of various complexities.

  7. Magnetically-controllable optical multi-stability in magneto-optic fiber Bragg gratings with potential applications to multi-level all-optical regeneration

    NASA Astrophysics Data System (ADS)

    Wan, Qing-Yao; Wu, Bao-Jian; Zhou, Xing-Yu; Wen, Feng

    2015-08-01

    Starting with the nonlinear coupled-mode equations of guided optical waves in the magneto-optic fiber Bragg grating (MFBG), the amplitude transfer curve of the transmitted light is numerically calculated for the incident right-circularly polarized wave, and the multi-stability is analyzed by introducing the parameter of jitter suppression. It is shown that, (i) the performance of amplitude jitter suppression in the stable states of high level is better than that of low level; (ii) the jitter suppression in the multi-stable regions can be enhanced when the magnetic field is applied to the MFBG in the opposite direction of the incident wave; and (iii) by adjusting the applied magnetic field, the multi-stable levels can be tuned flexibly, which is helpful for developing the intelligent all-optical devices for multilevel regeneration.

  8. The potential for optical beam shaping of UV laser sources for mass scale quarantine disinfection applications

    NASA Astrophysics Data System (ADS)

    Lizotte, Todd

    2010-08-01

    Recent events concerning H1N1 "swine flu", have demonstrated to the world the significant potential of rapid increases in death and illness among all age groups and even among the healthy population [1] when a highly infectious influenza virus is introduced. In terms of mass casualties due to a pandemic, preparedness and response planning must be done. One course of action to prevent a pandemic outbreak or reduce the impact of a bioterrorist event is the use of isolation or quarantine facilities. The first level of isolation or quarantine is within the personal residence of the person exposed or infected. In the case where, the specific virus is extremely contagious and its onset of symptoms is rapid and severe, there will be a need for the deployment and setup of larger self contained quarantine facilities. Such facilities are used to house infectious individuals to minimize the exposure of susceptible individuals to contagious individuals, especially when specialized care or treatment is required and during the viral shedding period (5 to 7 days). These types of facilities require non-shared air conditioning, heating and ventilating systems where 100% of air is vented to the outside through a series of disinfection systems and staged filters. Although chemical disinfection is possible, there is a desire to incorporate intense UV radiation as a means to deactivate and disinfect airborne virus within hospital settings and isolated mass scale quarantine facilities. UV radiation is also being considered for disinfection of contaminated surfaces, such as table tops, walls and floors in hospitals and temporary quarantine facilities. In such applications the use of UV bulb technology can create many problems, for instance bulb technology requires numerous bulbs to treat a large volume of air, generates significant heat, uses significant power and does not produce large fluxes of UV light efficiently. This paper provides several methods of creating quarantine level

  9. Enhanced α-particle optical potential at low energies, for the mass range A∼45-209

    SciTech Connect

    Avrigeanu, V.; Avrigeanu, M.; Mănăilescu, C.

    2015-02-24

    An updated optical potential is thus provided for α-particles on nuclei within the mass number range 45≤A≤209, below the Coulomb barrier (B), on the basis of recent high-precision measurements of α-particle induced reaction data below B that made possible the understanding of actual limits and possible improvement of the α-particle optical-model potentials. The main revision concerns actually only the surface imaginary potential depth at the lowest α-particle energies well below B, and in fact only for the mass range above A∼130. A further regional point is the underestimation of reaction cross sections for the rare-earth nuclei by using the spherical optical potential unless a 7% larger value of the surface imaginary potential radius is taken into account. Involvement of this potential for further description of both the scattering and α-particles induced reactions is moreover discussed in the present work, of equal interest for nuclear astrophysics and nuclear technology for fusion devices.

  10. The Potential Role of Drexon LaserCards in Optical Publishing.

    ERIC Educational Resources Information Center

    Schwerin, Julie B.

    1985-01-01

    Describes Drexon LaserCard (credit card size format holding two megabytes of digital data that can be recorded at factory or by information distributors) as a viable option to rotating optical media for distribution of computer software, technical manuals, periodicals, and other document applications, and projects its future in optical publishing.…

  11. Extracting Surface Activation Time from the Optically Recorded Action Potential in Three-Dimensional Myocardium

    PubMed Central

    Walton, Richard D.; Smith, Rebecca M.; Mitrea, Bogdan G.; White, Edward; Bernus, Olivier; Pertsov, Arkady M.

    2012-01-01

    Optical mapping has become an indispensible tool for studying cardiac electrical activity. However, due to the three-dimensional nature of the optical signal, the optical upstroke is significantly longer than the electrical upstroke. This raises the issue of how to accurately determine the activation time on the epicardial surface. The purpose of this study was to establish a link between the optical upstroke and exact surface activation time using computer simulations, with subsequent validation by a combination of microelectrode recordings and optical mapping experiments. To simulate wave propagation and associated optical signals, we used a hybrid electro-optical model. We found that the time of the surface electrical activation (tE) within the accuracy of our simulations coincided with the maximal slope of the optical upstroke (tF∗) for a broad range of optical attenuation lengths. This was not the case when the activation time was determined at 50% amplitude (tF50) of the optical upstroke. The validation experiments were conducted in isolated Langendorff-perfused rat hearts and coronary-perfused pig left ventricles stained with either di-4-ANEPPS or the near-infrared dye di-4-ANBDQBS. We found that tF∗ was a more accurate measure of tE than was tF50 in all experimental settings tested (P = 0.0002). Using tF∗ instead of tF50 produced the most significant improvement in measurements of the conduction anisotropy and the transmural conduction time in pig ventricles. PMID:22225795

  12. Theoretical description of two ultracold atoms in finite three-dimensional optical lattices using realistic interatomic interaction potentials

    SciTech Connect

    Grishkevich, Sergey; Sala, Simon; Saenz, Alejandro

    2011-12-15

    A theoretical approach is described for an exact numerical treatment of a pair of ultracold atoms interacting via a central potential and that are trapped in a finite three-dimensional optical lattice. The coupling of center-of-mass and relative-motion coordinates is treated using an exact diagonalization (configuration-interaction) approach. The orthorhombic symmetry of an optical lattice with three different but orthogonal lattice vectors is explicitly considered as is the fermionic or bosonic symmetry in the case of indistinguishable particles.

  13. Realization of non-PT -symmetric optical potentials with all-real spectra in a coherent atomic system

    NASA Astrophysics Data System (ADS)

    Hang, Chao; Gabadadze, Gregory; Huang, Guoxiang

    2017-02-01

    We present a physical setup for realizing all-real-spectrum optical potentials with arbitrary gain-and-loss distributions in a coherent medium consisting of a cold three-level atomic gas driven by control and probe laser fields. We show that by the interference of Raman resonances and the Stark shift induced by a far-detuned laser field, tunable, non-parity-time (non-PT )-symmetric optical potentials with all-real spectra proposed recently by Nixon and Yang [Phys. Rev. A 93, 031802(R) (2016), 10.1103/PhysRevA.93.031802] can be actualized physically. We also show that when the real parts of the non-PT -symmetric optical potentials are tuned cross certain thresholds, phase transitions—where the eigenspectrum of the system changes from all real to complex—may occur and hence the stability of the probe-field propagation is altered. Our scheme can also be extended to high dimensions and to a nonlinear propagation regime, where stable optical solitons with power of the order of nano-Watts may be generated in the system.

  14. Complementary optical-potential analysis of {alpha}-particle elastic scattering and induced reactions at low energies

    SciTech Connect

    Avrigeanu, M. Obreja, A.C.; Roman, F.L.; Avrigeanu, V.; Oertzen, W. von

    2009-07-15

    A previously derived semi-microscopic analysis based on the Double Folding Model, for {alpha}-particle elastic scattering on A{approx}100 nuclei at energies below 32 MeV, is extended to medium mass A{approx}50-120 nuclei and energies from {approx}13 to 50 MeV. The energy-dependent phenomenological imaginary part for this semi-microscopic optical model potential was obtained including the dispersive correction to the microscopic real potential, and used within a concurrent phenomenological analysis of the same data basis. A regional parameter set for low-energy {alpha}-particles entirely based on elastic scattering data analysis was also obtained for nuclei within the above mentioned mass and energy ranges. Then, an ultimate assessment of ({alpha},{gamma}), ({alpha},n), and ({alpha},p) reaction cross sections considered target nuclei from {sup 45}Sc to {sup 118}Sn and incident energies below {approx}12 MeV. The former diffuseness of the real part of optical potential as well as the surface imaginary potential depth have been found to be responsible for the actual difficulties in the description of these data, and modified in order to obtain an optical potential which describes equally well both the low-energy elastic scattering and induced reaction data for {alpha}-particles.

  15. Theoretical approach for optical response in electrochemical systems: Application to electrode potential dependence of surface-enhanced Raman scattering

    SciTech Connect

    Iida, Kenji; Noda, Masashi; Nobusada, Katsuyuki

    2014-09-28

    We propose a theoretical approach for optical response in electrochemical systems. The fundamental equation to be solved is based on a time-dependent density functional theory in real-time and real-space in combination with its finite temperature formula treating an electrode potential. Solvation effects are evaluated by a dielectric continuum theory. The approach allows us to treat optical response in electrochemical systems at the atomistic level of theory. We have applied the method to surface-enhanced Raman scattering (SERS) of 4-mercaptopyridine on an Ag electrode surface. It is shown that the SERS intensity has a peak as a function of the electrode potential. Furthermore, the real-space computational approach facilitates visualization of variation of the SERS intensity depending on an electrode potential.

  16. Parity-even and time-reversal-odd neutron optical potential in spinning matter induced by gravitational torsion

    NASA Astrophysics Data System (ADS)

    Ivanov, A. N.; Snow, W. M.

    2017-01-01

    Recent theoretical work has shown that spin 1/2 particles moving through unpolarized matter which sources torsion fields experience a new type of parity-even and time-reversal-odd optical potential if the matter is spinning in the lab frame. This new type of optical potential can be sought experimentally using the helicity dependence of the total cross sections for longitudinally polarized neutrons moving through a rotating cylindrical target. In combination with recent experimental constraints on short-range P-odd, T-even torsion interactions derived from polarized neutron spin rotation in matter one can derive separate constraints on the time components of scalar and pseudoscalar torsion fields in matter. We estimate the sensitivity achievable in such an experiment and briefly outline some of the potential sources of systematic error to be considered in any future experimental search for this effect.

  17. Wurtzite silicon as a potential absorber in photovoltaics: Tailoring the optical absorption by applying strain

    NASA Astrophysics Data System (ADS)

    Rödl, C.; Sander, T.; Bechstedt, F.; Vidal, J.; Olsson, P.; Laribi, S.; Guillemoles, J.-F.

    2015-07-01

    We present ab initio calculations of the electronic structure and the optical properties of wurtzite Si (Si-IV). We find an indirect band gap of 0.95 eV (Γ5→M1 ) and an optically forbidden direct gap of 1.63 eV (Γ5→Γ10 ), which is due to a backfolding of the L1 state of Si in the diamond structure (Si-I). Optical absorption spectra including excitonic and local-field effects are calculated. Further, the effects of hydrostatic pressure, uniaxial strain, and biaxial strain on the absorption properties are investigated. Biaxial tensile strains enhance the optical absorption of Si-IV in the spectral range which is relevant for photovoltaic applications. High biaxial tensile strains (>4 % ) even transform Si-IV into a direct semiconductor.

  18. Engineering Stark Potentials for Precision Measurements: Optical Lattice Clock and Electrodynamic Surface Trap

    SciTech Connect

    Katori, Hidetoshi; Takamoto, Masao; Hachisu, Hidekazu; Fujiki, Jun; Higashi, Ryoichi; Yasuda, Masami; Kishimoto, Tetsuo

    2005-05-05

    Employing the engineered electric fields, we demonstrate novel platforms for precision measurements with neutral atoms. (1) Applying the light shift cancellation technique, atoms trapped in an optical lattice reveal 50-Hz-narrow optical spectrum, yielding nearly an order of magnitude improvement over existing neutral-atom-based clocks. (2) Surface Stark trap has been developed to manipulate scalar atoms that are intrinsically robust to decoherence.

  19. Diagnostic potential of iris cross-sectional imaging in albinism using optical coherence tomography.

    PubMed

    Sheth, Viral; Gottlob, Irene; Mohammad, Sarim; McLean, Rebecca J; Maconachie, Gail D E; Kumar, Anil; Degg, Christopher; Proudlock, Frank A

    2013-10-01

    To characterize in vivo anatomic abnormalities of the iris in albinism compared with healthy controls using anterior segment optical coherence tomography (AS-OCT) and to explore the diagnostic potential of this technique for albinism. We also investigated the relationship between iris abnormalities and other phenotypical features of albinism. Prospective cross-sectional study. A total of 55 individuals with albinism and 45 healthy controls. We acquired 4.37×4.37-mm volumetric scans (743 A-scans, 50 B-scans) of the nasal and temporal iris in both eyes using AS-OCT (3-μm axial resolution). Iris layers were segmented and thicknesses were measured using ImageJ software. Iris transillumination grading was graded using Summers and colleagues' classification. Retinal OCT, eye movement recordings, best-corrected visual acuity (BCVA), visual evoked potential (VEP), and grading of skin and hair pigmentation were used to quantify other phenotypical features associated with albinism. Iris AS-OCT measurements included (1) total iris thickness, (2) stroma/anterior border (SAB) layer thickness, and (3) posterior epithelial layer (PEL) thickness. Correlation with other phenotypical measurements, including (1) iris transillumination grading, (2) retinal layer measurements at the fovea, (3) nystagmus intensity, (4) BCVA, (5) VEP asymmetry, (6) skin pigmentation, and (7) hair pigmentation (of head hair, lashes, and brows). The mean iris thickness was 10.7% thicker in controls (379.3 ± 44.0 μm) compared with the albinism group (342.5 ± 52.6 μm; P>0.001), SAB layers were 5.8% thicker in controls (315.1 ± 43.8 μm) compared with the albinism group (297.7 ± 50.0 μm; P=0.044), and PEL was 44.0% thicker in controls (64.1 ± 11.7 μm) compared with the albinism group (44.5 ± 13.9 μm; P<0.0001). The most ciliary quartile of the PEL yielded a sensitivity of 85% and specificity of 78% for detecting albinism. Phenotypic features of albinism, such as skin and hair pigmentation, BCVA

  20. Pattern visual evoked potentials represent an early index for the evolution of optic chiasma syndrome of tumoral etiology.

    PubMed

    Badiu, C; Serbănescu, A; Coculescu, M

    1996-01-01

    The use of visual evoked potentials in the detection of optic chiasma syndrome of tumoral etiology has been controversial in the literature. In our study the pattern visual evoked potentials (PVEP) were recorded in 22 healthy free volunteers and in 32 patients with optic chiasma syndrome (OCS) produced by tumors of the hypothalamic-pituitary area, mainly pituitary adenomas with suprasellar extension, proved by CT scan. The PVEP were recorded bilateral after monocular photic stimulation of each atropinized eye, in parallel with a complete ophthalmologic exam consisting in visual field, visual acuity and optic fundus. The main results showed that the latencies P100 recorded bilateral were correlated (p < 0.01) with the types of visual field deficiency, in each hemifield. The changes in P100 latency are more sensitive than the evolution of visual field deficiency by campimetry. The same correlation was observed between the "W" form of P wave with the visual field defect. A significant decrease (p < 0.05) of the amplitude of P100 was observed only if the visual acuity was less than 1/2. It is suggested that the PVEP is a reliable index of diagnosis and evolution for the optic chiasma syndrome aside the usual ophthalmologic exam.

  1. Photoresist outgassing: a potential Achilles heel for short-wavelength optical lithography?

    NASA Astrophysics Data System (ADS)

    Kunz, Roderick R.

    2004-05-01

    The outgassing of volatile organic compounds during photoresist exposure at short wavelengths (<200 nm) has in recent years become a cause for concern as a source for contamination of lithographic optics and has triggered a significant investment of resources to understand and address the problem. In this paper, we report on Lincoln Laboratory"s contribution to this industry-wide effort with results from two types of outgassing measurements aimed at providing a better understanding of the risk posed by this phenomenon. The first method is a quantitative measurement based on a gas chromatograph-mass spectrometer and measures the outgassing by collecting the vapor sample over several minutes in order to enhance sensitivity. This first method cannot determine the outgassing time dependence over the duration of the exposure (~seconds). Our second method, based on laser desorption mass spectrometry, has been performed under UHV conditions to determine the time-dependence of photoresist outgassing and has shown that, for both 193- and 157-nm exposures, a majority of the total outgassed vapor is desorbed during the exposure time. The time dependence of the remaining amount that outgasses after exposure can be fit to a double exponential with characteristic time constants of ~0.5 and ~3 seconds, indicating that even in the limiting case of very short exposures (<<1 second), most material (>50%) would outgas within seconds. The implications of these findings are twofold. First, analytical methods used to measure outgassing that rely on long (>10 minute) sample collection and preconcentration steps must now assume that the measured product is liberated over a few-second time frame when converting the data to outgassing rates. This means that the peak transient outgassing rates for the few seconds during and immediately after exposure derived using this corrected method could be hundreds of times higher than previously reported, with values approaching as much as 1014

  2. Energy dependence of the optical potential of weakly and tightly bound nuclei as projectiles on a medium-mass target

    SciTech Connect

    Figueira, J. M.; Arazi, A.; Carnelli, P.; Heimann, D. Martinez; Negri, A. E.; Pacheco, A. J.; Niello, J. O. Fernandez; Capurro, O. A.; Fimiani, L.; Marti, G. V.; Lubian, J.; Monteiro, D. S.; Gomes, P. R. S.

    2010-02-15

    Angular distributions for the elastic scattering of the weakly bound {sup 6,7}Li+{sup 144}Sm systems were measured with high accuracy at bombarding energies from 85% up to 170% of the Coulomb barrier. An optical model analysis was performed, and the relevant parameters of the real and imaginary parts of the optical potential were extracted. The results are compared with those previously published for the tightly bound {sup 12}C+{sup 144}Sm and {sup 16}O+{sup 144}Sm systems. The usual threshold anomaly observed in the behavior of the potential of tightly bound systems was not observed for either weakly bound system. This absence is attributed to the repulsion due to breakup coupling which cancels the attraction arising from couplings with bound channels.

  3. Van der Waals enhancement of optical atom potentials via resonant coupling to surface polaritons.

    PubMed

    Kerckhoff, Joseph; Mabuchi, Hideo

    2009-08-17

    Contemporary experiments in cavity quantum electrodynamics (cavity QED) with gas-phase neutral atoms rely increasingly on laser cooling and optical, magneto-optical or magnetostatic trapping methods to provide atomic localization with sub-micron uncertainty. Difficult to achieve in free space, this goal is further frustrated by atom-surface interactions if the desired atomic placement approaches within several hundred nanometers of a solid surface, as can be the case in setups incorporating monolithic dielectric optical resonators such as microspheres, microtoroids, microdisks or photonic crystal defect cavities. Typically in such scenarios, the smallest atom-surface separation at which the van der Waals interaction can be neglected is taken to be the optimal localization point for associated trapping schemes, but this sort of conservative strategy generally compromises the achievable cavity QED coupling strength. Here we suggest a new approach to the design of optical dipole traps for atom confinement near surfaces that exploits strong surface interactions, rather than avoiding them, and present the results of a numerical study based on (39)K atoms and indium tin oxide (ITO). Our theoretical framework points to the possibility of utilizing nanopatterning methods to engineer novel modifications of atom-surface interactions. (c) 2009 Optical Society of America

  4. Optical Model Potential Parameters for p, d, {sup 3}He and Alpha-Particle Scattering on Lithium Nuclei

    SciTech Connect

    Burtebayev, N.; Nassurlla, Marzhan; Nassurlla, Maulen; Kerimkulov, Zh. K.; Sakuta, S. B.

    2008-11-11

    Analysis of the p, d, {sup 3}He and {alpha}-particles elastic scattering on the {sup 6}Li and {sup 7}Li nuclei has been done in the framework of the optical model at the beam energies up to 72 MeV. It was shown that the account of the cluster exchange mechanism together with the potential scattering allow reproducing the experimental cross-sections in the whole angular range.

  5. Retention of indocyanine green as a potential marker for optical detection of blood brain barrier disruption

    NASA Astrophysics Data System (ADS)

    Ergin, A.; Joshi, S.; Wang, M.; Bigio, I. J.

    2011-03-01

    Preliminary studies have shown that there is great variability in the degree of disruption of blood-brain barrier (BBBD) after the intraarterial injection of mannitol in rabbit models. The disruption of blood-brain barrier (BBB) is affected by a number of factors, and the variations could have a profound impact on regional delivery of chemotherapeutics. Optically measured brain tissue concentrations of indocyanine green (ICG) and Evan's blue (EB) enable the quantification of BBBD after intraarterial administration of mannitol. Using the optical pharmacokinetics technique, a variation of diffuse reflectance spectroscopy, we are able to track in vivo brain tissue concentrations of ICG and EB in rabbits, before and after barrier disruption. This study shows the feasibility of optical monitoring of BBBD, a method that can help improve intraarterial delivery of chemotherapeutic drugs.

  6. Traumatic Optic Neuropathy: A Potentially Unrecognized Diagnosis after Sports-Related Concussion.

    PubMed

    Ellis, Michael J; Ritchie, Lesley; Cordingley, Dean; Essig, Marco; Mansouri, Behzad

    2016-01-01

    Traumatic optic neuropathy is a rare cause of visual disturbance after head injury that can be difficult to distinguish from coexisting vestibulo-ocular dysfunction because of the overlap in presenting symptoms in patients with these conditions. We present a case report of a 13-year-old girl who sustained a head injury during a ringette game leading to blurred vision and diplopia persisting 5 months after injury. Clinical history and physical examination findings were consistent with a traumatic optic neuropathy, convergence insufficiency, and postconcussion syndrome. Neuroimaging was normal. The patient was managed using a multidisciplinary approach. At 6 months of follow-up, neuro-ophthalmological examination demonstrated evidence of permanent partial optic nerve injury, and formal neuropsychological testing fell primarily within normal limits. The patient was advised to retire from collision sports. The authors discuss the value of a comprehensive multidisciplinary approach to the evaluation and management of concussion patients presenting with persistent visual symptoms.

  7. Analysis of the potential-dependent changes in optical retardation in the squid giant axon.

    PubMed

    Cohen, L B; Hille, B; Keynes, R D; Landowne, D; Rojas, E

    1971-10-01

    1. An analysis has been made of the change in optical retradation of the membrane elicited by the application of voltage-clamp pulses in squid giant axons.2. The retardation response consists of three separate voltage-dependent components. For freshly mounted axons, defined as being in state 1, hyperpolarizing pulses give a rapid increase in the light intensity measured with crossed polarizers which has been termed the fast phase. This is followed by a rather slow return towards the base line termed the rebound. On treatment of the axon with certain agents that include tetrodotoxin, high calcium and terbium, the rebound disappears and the fast phase slows down, increases in size, and has a new slow component added to it. This transition from state 1 to a second state, 2, appears to be irreversible.3. In state 1, the time constant of the fast phase is 20-40 musec at 13 degrees C; it has a very large negative temperature coefficient (Q(10) = Ca.(1/8)). The size of the retardation change is independent of temperature and varies as the square of the applied voltage, but the voltage-retardation curve is symmetrical about a point well beyond zero membrane potential, at an internal potential of around + 70 mV. In state 2, the time constant is about five times larger, and varies much less markedly with temperature; the apex of the voltage-retardation curve is shifted to + 200 mV.4. The rebound has a time constant of the order of 20 msec at 13 degrees C. A 10 degrees rise in temperature more than halves the time constant and roughly doubles the amplitude of the rebound. The voltage dependence of the rebound differed from that of the fast phase.5. The slow component of state 2 has a time constant of about 2 msec which does not change noticeably between 10 and 25 degrees C. The size of this component seems to be linearly dependent on the applied voltage, rather than obeying a square law.6. A tenfold increase in external calcium concentration had no discernible effect on the

  8. Sensitivity of visual evoked potentials and spectral domain optical coherence tomography in early relapsing remitting multiple sclerosis.

    PubMed

    Behbehani, Raed; Ahmed, Samar; Al-Hashel, Jasem; Rousseff, Rossen T; Alroughani, Raed

    2017-02-01

    Visual evoked potentials and spectral-domain optical coherence tomography are common ancillary studies that assess the visual pathways from a functional and structural aspect, respectively. To compare prevalence of abnormalities of Visual evoked potentials (VEP) and spectral-domain optical coherence tomography (SDOCT) in patients with relapsing remitting multiple sclerosis (RRMS). A cross-sectional study of 100 eyes with disease duration of less than 5 years since the diagnosis. Correlation between retinal nerve fiber layer and ganglion-cell/inner plexiform layer with pattern-reversal visual evoked potentials amplitude and latency and contrast sensitivity was performed. The prevalence of abnormalities in pattern-reversal visual VEP was 56% while that of SOCT was 48% in all eyes. There was significant negative correlations between the average RNFL (r=-0.34, p=0.001) and GCIPL (r=-0.39, p<0.001) with VEP latency. In eyes with prior optic neuritis, a significant negative correlation was seen between average RNFL (r=-0.33, p=0.037) and GCIPL (r=-0.40, p=0.010) with VEP latency. We have found higher prevalence of VEP abnormalities than SCOCT in early relapsing-remitting multiple sclerosis. This suggests that VEP has a higher sensitivity for detecting lesions of the visual pathway in patients with early RRMS. Copyright © 2016 Elsevier B.V. All rights reserved.

  9. Optical signatures of a hypercritical 1D potential in a 2D Dirac metal

    NASA Astrophysics Data System (ADS)

    Jiang, Bor-Yuan; Ni, Guangxin; Pan, Cheng; Fei, Zhe; Cheng, Bin; Lau, Chun Ning; Bockrath, Marc; Basov, Dimitri; Fogler, Michael

    Generation of quasi-bound states in graphene near strong charged perturbations is a solid-state analog of atomic collapse of superheavy elements or particle production by hypothetical cosmic strings. We show, for the case of a linelike perturbation, that as the perturbation grows in strength, quasi-bound states are generated sequentially. Each of these critical events is signaled by a sharp change in the local optical conductivity. Tunable linelike perturbations can be realized in experiment using nanowire or nanotube electrostatic gates. We report measurements of local conductivity for such systems obtained through near-field optical microscopy.

  10. Calculation of eta-meson-nucleus quasibound states with optical potentials of the square-well and woods-saxon forms

    SciTech Connect

    Tryasuchev, V. A.; Isaev, A. V.

    2010-11-15

    The results obtained by calculating bound states of eta mesons and nuclei by using a squarewell optical potential are compared with their counterparts based on the use of an optical potential in the Woods-Saxon form. For any reasonable choice of range for a potential that has a sharp boundary, the results for the case of a diffuse boundary demonstrate the need for a greater baryon charge in order that an eta meson form a bound state with nuclei. The dependence of the probability for the formation of etamesonic nuclei on the diffuseness parameter of the optical potential involving the Woods-Saxon radial dependence is revealed.

  11. Potential science for the OASIS integral field spectrograph with laser guide star adaptive optics

    NASA Astrophysics Data System (ADS)

    Morris, Simon L.; Gerssen, Joris; Swinbank, Mark; Wilman, Richard

    2006-01-01

    I review the science case for the Laser Guide Star system being built for the William Herschel Telescope on La Palma. When used in combination with the NAOMI Adaptive Optics system and the OASIS visible-wavelength Integral Field Spectrograph, I demonstrate that there are substantial, exciting areas of astrophysical research in which the WHT can contribute.

  12. Modal liquid crystal devices in optical tweezing: 3D control and oscillating potential wells

    NASA Astrophysics Data System (ADS)

    Hands, Philip J. W.; Tatarkova, Svetlana A.; Kirby, Andrew K.; Love, Gordon D.

    2006-05-01

    We investigate the use of liquid crystal (LC) adaptive optics elements to provide full 3 dimensional particle control in an optical tweezer. These devices are suitable for single controllable traps, and so are less versatile than many of the competing technologies which can be used to control multiple particles. However, they have the advantages of simplicity and light efficiency. Furthermore, compared to binary holographic optical traps they have increased positional accuracy. The transmissive LC devices could be retro-fitted to an existing microscope system. An adaptive modal LC lens is used to vary the z-focal position over a range of up to 100 μm and an adaptive LC beam-steering device is used to deflect the beam (and trapped particle) in the x-y plane within an available radius of 10 μm. Furthermore, by modifying the polarisation of the incident light, these LC components also offer the opportunity for the creation of dual optical traps of controllable depth and separation.

  13. Modal liquid crystal devices in optical tweezing: 3D control and oscillating potential wells.

    PubMed

    Hands, Philip J W; Tatarkova, Svetlana A; Kirby, Andrew K; Love, Gordon D

    2006-05-15

    We investigate the use of liquid crystal (LC) adaptive optics elements to provide full 3 dimensional particle control in an optical tweezer. These devices are suitable for single controllable traps, and so are less versatile than many of the competing technologies which can be used to control multiple particles. However, they have the advantages of simplicity and light efficiency. Furthermore, compared to binary holographic optical traps they have increased positional accuracy. The transmissive LC devices could be retro-fitted to an existing microscope system. An adaptive modal LC lens is used to vary the z-focal position over a range of up to 100 mum and an adaptive LC beam-steering device is used to deflect the beam (and trapped particle) in the x-y plane within an available radius of 10 mum. Furthermore, by modifying the polarisation of the incident light, these LC components also offer the opportunity for the creation of dual optical traps of controllable depth and separation.

  14. Dye-modified ZnO nanohybrids: optical properties of the potential solar cell nanocomposites

    NASA Astrophysics Data System (ADS)

    Ayinde, Wasiu B.; Dare, Enock O.; Bada, Damilola A.; Alayande, Samson O.; Oladoyinbo, Fatai O.; Idowu, Mopelola A.; Bolaji, Bukola. O.; Ezeh, Miriam I.; Osuji, Rose U.

    2017-06-01

    We report the hybridization of ZnO with natural dyes [Laali, Zobo] or synthetic dye [methyl red] forming ZnO-laali, ZnO-zobo and ZnO-methyl red nanocomposites in bright colours. The structural, optical and dye photosensitization influence of the hybrid nanocomposites were studied by X-ray diffraction (XRD), scanning electron microscope (SEM), UV-Visible absorption spectroscopy and photoluminescence (PL). The surface plasmon absorption band of ZnO-laali and ZnO-zobo shifts towards red and blue, respectively, with significantly enhanced absorption intensities, indicating the interaction and optical influence of the respective dyes in photosensitization. Optical and absorption character of ZnO methyl red and bare ZnO are similar indicating the insignificant effect of methyl red on photosensitization. PL spectra of ZnO-laali and ZnO-zobo display enhanced UV light emission due not only to the surface electron transfer from their respective inherent isoplumbagin and anthocyanin to ZnO but also to the extension of the Fermi energy level to the ZnO. Dyes adopted influence the optical band gaps of the evolved hybrid nanocomposites.

  15. Application of shadow Doppler velocimetry to paint spray: potential and limitations in sizing optically inhomogeneous droplets

    NASA Astrophysics Data System (ADS)

    Morikita, Hiroshi; Taylor, Alexander M. K. P.

    1998-02-01

    This paper reports size measurement of droplets with optically inhomogeneous media by shadow Doppler velocimetry (SDV), which can provide spatially and temporally precise in situ readings of the size and velocity of a single particle with irregular shape and with arbitrary optical properties of the particle medium. In this work, water, instant coffee solution and water-based paint with various solid contents were measured to evaluate the capability and limitations of the measurement. The experiment with instant coffee solutions of 2 and 5% (wt:wt), which contained 0957-0233/9/2/009/img1m discrete particles, atomized by a standard paint spray gun, demonstrated that the accuracy of sizing was not affected by the optical properties of the medium. Insensitivity to the optical properties is one of the primary advantages of SDV over the other optical, single-particle sizing methods. As a further demonstration, paint samples atomized by the same gun containing solid flakes of nominal diameter 0957-0233/9/2/009/img2m were also measured. The results revealed a spatially uniform arithmetic mean diameter of 0957-0233/9/2/009/img3m and suggested that the atomization characteristics were influenced in the highest flake volume fraction case (red paint containing mica, 1.5%) with the result that the mean diameter was 20% larger than that of a similar paint with a smaller flake volume fraction (green paint containing aluminium, 0.4%). It was also found that the measurable number density is limited to no more than 1000 droplets 0957-0233/9/2/009/img4 in the case of droplets with an average size of 0957-0233/9/2/009/img5m.

  16. Potential of a spectroscopic measurement method using adding-doubling to retrieve the bulk optical properties of dense microalgal media.

    PubMed

    Bellini, Sarah; Bendoula, Ryad; Latrille, Eric; Roger, Jean-Michel

    2014-01-01

    In the context of algal mass cultivation, current techniques used for the characterization of algal cells require time-consuming sample preparation and a large amount of costly, standard instrumentation. As the physical and chemical properties of the algal cells strongly affect their optical properties, the optical characterization is seen as a promising method to provide an early diagnosis in the context of mass cultivation monitoring. This article explores the potential of a spectroscopic measurement method coupled with the inversion of the radiative transfer theory for the retrieval of the bulk optical properties of dense algal samples. Total transmittance and total reflectance measurements were performed over the 380-1020 nm range on dense algal samples with a double integrating sphere setup. The bulk absorption and scattering coefficients were thus extracted over the 380-1020 nm range by inverting the radiative transfer theory using inverse-adding-doubling computations. The experimental results are presented and discussed; the configuration of the optical setup remains a critical point. The absorption coefficients obtained for the four samples of this study appear not to be more informative about pigment composition than would be classical methods in analytical spectroscopy; however, there is a real added value in measuring the reduced scattering coefficient, as it appears to be strongly correlated to the size distribution of the algal cells.

  17. Vortical Solitons of Three-Dimensional Bose—Einstein Condensates under Both a Bichromatic Optical Lattice and Anharmonic Potentials

    NASA Astrophysics Data System (ADS)

    Li, Feng-Bo; Zong, Feng-De; Wang, Ying

    2013-06-01

    We study Bose—Einstein condensate vortical solitons under both a bichromatic optical lattice and anharmonic potential. The vortical solitons are built in the form of a layer-chain structure made up of two fundamental vortices along the bichromatic optical lattice direction, which have not been reported before in the three-dimensional Bose—Einstein condensate. A variation approach is applied to find the optimum initial solutions of vortical solitons. The stabilities of the vortical solitons are confirmed by the numerical simulation of the time-dependent Gross—Pitaevskii equation. In particular, stable Bose—Einstein condensate vortical solitons with fundamental vortices of different atomic numbers in the external potential within a range of experimentally achievable timescales are found. We further manipulate the vortical solitons to an arbitrary position by steadily moving the bichromatic optical lattice, and find a stable region for the successful manipulation of vortical solitons without collapse. These results provide insight into controlling and manipulating the Bose—Einstein condensate vortical solitons for macroscopic quantum applications.

  18. Acute Effect of Pore-Forming Clostridium perfringens ε-Toxin on Compound Action Potentials of Optic Nerve of Mouse.

    PubMed

    Cases, Mercè; Llobet, Artur; Terni, Beatrice; Gómez de Aranda, Inmaculada; Blanch, Marta; Doohan, Briain; Revill, Alexander; Brown, Angus M; Blasi, Juan; Solsona, Carles

    2017-01-01

    ε-Toxin is a pore forming toxin produced by Clostridium perfringens types B and D. It is synthesized as a less active prototoxin form that becomes fully active upon proteolytic activation. The toxin produces highly lethal enterotoxaemia in ruminants, has the ability to cross the blood-brain barrier (BBB) and specifically binds to myelinated fibers. We discovered that the toxin induced a release of ATP from isolated mice optic nerves, which are composed of myelinated fibers that are extended from the central nervous system. We also investigated the effect of the toxin on compound action potentials (CAPs) in isolated mice optic nerves. When nerves were stimulated at 100 Hz during 200 ms, the decrease of the amplitude and the area of the CAPs was attenuated in the presence of ε-toxin. The computational modelling of myelinated fibers of mouse optic nerve revealed that the experimental results can be mimicked by an increase of the conductance of myelin and agrees with the pore forming activity of the toxin which binds to myelin and could drill it by making pores. The intimate ultrastructure of myelin was not modified during the periods of time investigated. In summary, the acute action of the toxin produces a subtle functional impact on the propagation of the nerve action potential in myelinated fibers of the central nervous system with an eventual desynchronization of the information. These results may agree with the hypothesis that the toxin could be an environmental trigger of multiple sclerosis (MS).

  19. Transparent half metallic g-C4N3 nanotubes: potential multifunctional applications for spintronics and optical devices.

    PubMed

    Hu, Tao; Hashmi, Arqum; Hong, Jisang

    2014-08-14

    Multifunctional material brings many interesting issues because of various potential device applications. Using first principles calculations, we predict that the graphitic carbon nitride (g-C4N3) nanotubes can display multifunctional properties for both spintronics and optical device applications. Very interestingly, armchair tubes (n, n) with n = 2, 3, 4, 5, 6 and (5, 0) zigzag tubes are found to be half metallic, while zigzag tubes (n, 0) with n = 4, 6 show an antiferromagnetic ground state with band gaps. However, larger zigzag tubes of (7, 0), (8, 0), and (10, 0) are turned out to be half metallic. Along with the half metallic behavior of the tubes, those tubes seem to be optically transparent in the visible range. Due to these magnetic and optical properties, we suggest that the g-C4N3 nanotubes (CNNTs) can be used for both ideal spintronics and transparent electrode materials. We also explored the stability of magnetic state and nanotube structure using ab initio molecular dynamics. The CNNTs were found to be thermally stable and the magnetic moment was robust against the structural deformation at 300 K. Overall, our theoretical prediction in one dimensional CNNTs may provide a new physics in spintronics and also in other device applications because of potential multifunctional properties.

  20. Transparent half metallic g-C4N3 nanotubes: potential multifunctional applications for spintronics and optical devices

    NASA Astrophysics Data System (ADS)

    Hu, Tao; Hashmi, Arqum; Hong, Jisang

    2014-08-01

    Multifunctional material brings many interesting issues because of various potential device applications. Using first principles calculations, we predict that the graphitic carbon nitride (g-C4N3) nanotubes can display multifunctional properties for both spintronics and optical device applications. Very interestingly, armchair tubes (n, n) with n = 2, 3, 4, 5, 6 and (5, 0) zigzag tubes are found to be half metallic, while zigzag tubes (n, 0) with n = 4, 6 show an antiferromagnetic ground state with band gaps. However, larger zigzag tubes of (7, 0), (8, 0), and (10, 0) are turned out to be half metallic. Along with the half metallic behavior of the tubes, those tubes seem to be optically transparent in the visible range. Due to these magnetic and optical properties, we suggest that the g-C4N3 nanotubes (CNNTs) can be used for both ideal spintronics and transparent electrode materials. We also explored the stability of magnetic state and nanotube structure using ab initio molecular dynamics. The CNNTs were found to be thermally stable and the magnetic moment was robust against the structural deformation at 300 K. Overall, our theoretical prediction in one dimensional CNNTs may provide a new physics in spintronics and also in other device applications because of potential multifunctional properties.

  1. Transparent half metallic g-C4N3 nanotubes: potential multifunctional applications for spintronics and optical devices

    PubMed Central

    Hu, Tao; Hashmi, Arqum; Hong, Jisang

    2014-01-01

    Multifunctional material brings many interesting issues because of various potential device applications. Using first principles calculations, we predict that the graphitic carbon nitride (g-C4N3) nanotubes can display multifunctional properties for both spintronics and optical device applications. Very interestingly, armchair tubes (n, n) with n = 2, 3, 4, 5, 6 and (5, 0) zigzag tubes are found to be half metallic, while zigzag tubes (n, 0) with n = 4, 6 show an antiferromagnetic ground state with band gaps. However, larger zigzag tubes of (7, 0), (8, 0), and (10, 0) are turned out to be half metallic. Along with the half metallic behavior of the tubes, those tubes seem to be optically transparent in the visible range. Due to these magnetic and optical properties, we suggest that the g-C4N3 nanotubes (CNNTs) can be used for both ideal spintronics and transparent electrode materials. We also explored the stability of magnetic state and nanotube structure using ab initio molecular dynamics. The CNNTs were found to be thermally stable and the magnetic moment was robust against the structural deformation at 300 K. Overall, our theoretical prediction in one dimensional CNNTs may provide a new physics in spintronics and also in other device applications because of potential multifunctional properties. PMID:25317598

  2. Potential clinical utility of a fibre optic-coupled dosemeter for dose measurements in diagnostic radiology.

    PubMed

    Jones, A Kyle; Hintenlang, David

    2008-01-01

    Many types of dosemeters have been investigated for absorbed dose measurements in diagnostic radiology, including ionisation chambers, metal-oxide semiconductor field-effect transistor dosemeters, thermoluminescent dosemeters, optically stimulated luminescence detectors, film and diodes. Each of the aforementioned dosemeters suffers from a critical limitation, either the need to interrogate, or read, the dosemeter to retrieve dose information or large size to achieve adequate sensitivity. This work presents an evaluation of a fibre optic-coupled dosemeter (FOCD) for use in diagnostic radiology dose measurement. This dosemeter is small, tissue-equivalent and capable of providing true real-time dose information. The FOCD has been evaluated for dose linearity, angular dependence, sensitivity and energy dependence at energies, beam qualities and beam quantities relevant to diagnostic radiology. The FOCD displayed excellent dose linearity and high sensitivity, while exhibiting minimal angular dependence of response. However, the dosemeter does exhibit positive energy dependence, and is subject to attenuation of response when bent.

  3. Semiconducting Polymer Nanoparticles with Persistent Near-infrared Luminescence Show Potential for In Vivo Optical Imaging**

    PubMed Central

    Palner, Mikael; Pu, Kanyi; Shao, Shirley

    2015-01-01

    Materials with persistent luminescence are attractive for in vivo optical imaging since they have a long lifetime that allows the separation of excitation of fluorophores and image acquisition for time-delay imaging, thus eliminating tissue autofluorescence associated with fluorescence imaging. Persistently luminescent nanoparticles have previously been fabricated from toxic rare-earth metals. This work reports that nanoparticles made of the conjugated polymer MEH-PPV can generate luminescence persisting for an hour long upon single excitation. A near-infrared dye was encapsulated in the conjugated polymer nanoparticle to successfully generate persistent near-infrared luminescence through resonance energy transfer. This new persistent luminescence nanoparticles have been demonstrated for optical imaging applications in living mice. PMID:26223794

  4. Optical coherence tomography findings in Huntington's disease: a potential biomarker of disease progression.

    PubMed

    Kersten, Hannah M; Danesh-Meyer, Helen V; Kilfoyle, Dean H; Roxburgh, Richard H

    2015-11-01

    Previous reports of ocular abnormalities in Huntington's disease (HD) have detailed eye movement disorders. The objective of this case-control study was to investigate optic nerve and macular morphology in HD using optical coherence tomography (OCT). A total of 26 HD patients and 29 controls underwent a thorough ophthalmic examination including spectral domain OCT scans of the macula and peripapillary retinal nerve fibre layer (RNFL). Genetic testing results, disease duration, HD disease burden scores and Unified HD Rating Scale motor scores were acquired for HD patients. Temporal RNFL thickness was significantly reduced in the HD group (62.3 vs. 69.8 μm, p = 0.005), and there was a significant negative correlation between temporal RNFL thickness and disease duration (R (2) = -0.51, p = 0.04). Average peripapillary RNFL thickness was not significantly different between the HD and control groups. There was a significant negative correlation between macular volume and disease duration (R (2) = -0.71, p = 0.002), and motor scores (R (2) = -0.56, p = 0.01). Colour vision was significantly poorer in the HD group. Temporal RNFL is preferentially thinned in HD patients, possibly implicating mitochondrial dysfunction as the temporal RNFL is reduced in the patients with some mitochondrial disorders, including Leber's hereditary optic neuropathy. The correlation between the decrease in macular volume and temporal RNFL, and increasing disease severity suggests that OCT may be a useful biomarker for disease progression in HD. Larger, longitudinal studies are required.

  5. Potential of optical spectral transmission measurements for joint inflammation measurements in rheumatoid arthritis patients

    NASA Astrophysics Data System (ADS)

    Meier, A. J. Louise; Rensen, Wouter H. J.; de Bokx, Pieter K.; de Nijs, Ron N. J.

    2012-08-01

    Frequent monitoring of rheumatoid arthritis (RA) patients enables timely treatment adjustments and improved outcomes. Currently this is not feasible due to a shortage of rheumatologists. An optical spectral transmission device is presented for objective assessment of joint inflammation in RA patients, while improving diagnostic accuracy and clinical workflow. A cross-sectional, nonrandomized observational study was performed with this device. In the study, 77 proximal interphalangeal (PIP) joints in 67 patients have been analyzed. Inflammation of these PIP joints was also assessed by a rheumatologist with a score varying from 1 (not inflamed) to 5 (severely inflamed). Out of 77 measurements, 27 were performed in moderate to strongly inflamed PIP joints. Comparison between the clinical assessment and an optical measurement showed a correlation coefficient r=0.63, p<0.001, 95% CI [0.47, 0.75], and a ROC curve (AUC=0.88) that shows a relative good specificity and sensitivity. Optical spectral transmission measurements in a single joint correlate with clinical assessment of joint inflammation, and therefore might be useful in monitoring joint inflammation in RA patients.

  6. Potentials of radial partially coherent beams in free-space optical communication: a numerical investigation.

    PubMed

    Wang, Minghao; Yuan, Xiuhua; Ma, Donglin

    2017-04-01

    Nonuniformly correlated partially coherent beams (PCBs) have extraordinary propagation properties, making it possible to further improve the performance of free-space optical communications. In this paper, a series of PCBs with varying degrees of coherence in the radial direction, academically called radial partially coherent beams (RPCBs), are considered. RPCBs with arbitrary coherence distributions can be created by adjusting the amplitude profile of a spatial modulation function imposed on a uniformly correlated phase screen. Since RPCBs cannot be well characterized by the coherence length, a modulation depth factor is introduced as an indicator of the overall distribution of coherence. By wave optics simulation, free-space and atmospheric propagation properties of RPCBs with (inverse) Gaussian and super-Gaussian coherence distributions are examined in comparison with conventional Gaussian Schell-model beams. Furthermore, the impacts of varying central coherent areas are studied. Simulation results reveal that under comparable overall coherence, beams with a highly coherent core and a less coherent margin exhibit a smaller beam spread and greater on-axis intensity, which is mainly due to the self-focusing phenomenon right after the beam exits the transmitter. Particularly, those RPCBs with super-Gaussian coherence distributions will repeatedly focus during propagation, resulting in even greater intensities. Additionally, RPCBs also have a considerable ability to reduce scintillation. And it is demonstrated that those properties have made RPCBs very effective in improving the mean signal-to-noise ratio of small optical receivers, especially in relatively short, weakly fluctuating links.

  7. Challenges in Ecohydrological Monitoring at Soil-Vegetation Interfaces: Exploiting the Potential for Fibre Optic Technologies

    NASA Astrophysics Data System (ADS)

    Chalari, A.; Ciocca, F.; Krause, S.; Hannah, D. M.; Blaen, P.; Coleman, T. I.; Mondanos, M.

    2015-12-01

    The Birmingham Institute of Forestry Research (BIFoR) is using Free-Air Carbon Enrichment (FACE) experiments to quantify the long-term impact and resilience of forests into rising atmospheric CO2 concentrations. The FACE campaign critically relies on a successful monitoring and understanding of the large variety of ecohydrological processes occurring across many interfaces, from deep soil to above the tree canopy. At the land-atmosphere interface, soil moisture and temperature are key variables to determine the heat and water exchanges, crucial to the vegetation dynamics as well as to groundwater recharge. Traditional solutions for monitoring soil moisture and temperature such as remote techniques and point sensors show limitations in fast acquisition rates and spatial coverage, respectively. Hence, spatial patterns and temporal dynamics of heat and water fluxes at this interface can only be monitored to a certain degree, limiting deeper knowledge in dynamically evolving systems (e.g. in impact of growing vegetation). Fibre optics Distributed Temperature Sensors (DTS) can measure soil temperatures at high spatiotemporal resolutions and accuracy, along kilometers of optical cable buried in the soil. Heat pulse methods applied to electrical elements embedded in the optical cable can be used to obtain the soil moisture. In July 2015 a monitoring system based on DTS has been installed in a recently forested hillslope at BIFoR in order to quantify high-resolution spatial patterns and high-frequency temporal dynamics of soil heat fluxes and soil moisture conditions. Therefore, 1500m of optical cables have been carefully deployed in three overlapped loops at 0.05m, 0.25m and 0.4m from the soil surface and an electrical system to send heat pulses along the optical cable has been developed. This paper discussed both, installation and design details along with first results of the soil moisture and temperature monitoring carried out since July 2015. Moreover, interpretations

  8. Correction of Doi-Edwards' Green function in harmonic potential and its implication for stress-optical rule

    NASA Astrophysics Data System (ADS)

    Indei, Tsutomu; Schieber, Jay

    2013-03-01

    We derive a corrected Green's function for a polymer chain trapped in a two-dimensional anisotropic harmonic potential with a fixed boundary condition. This Green's function is a modified version of what Doi and Edwards first derived to describe the polymer chain trapped in the tube-like domain of surrounding entangled polymers [J. Chem. Soc. Farad. Trans. II 74 (1978) 1802]. In contradiction to the results found by Ianniruberto and Marrucci using the incorrect Green's function [J. Non-Newtonian Fluid Mech. 79 (1998) 225], we find that the stress-optical rule is violated for any tube potential either circular or elliptic. The violation is due to the presence of the virtual springs to trap the chain in the tube rather than the anisotropy of the confinement potential. Army Research Office (grants W911NF-08-2-0058 and W911NF-09-1-0378)

  9. Magneto-optical absorption in semiconducting spherical quantum dots: Influence of the dot-size, confining potential, and magnetic field

    NASA Astrophysics Data System (ADS)

    Kushwaha, Manvir S.

    2014-12-01

    Semiconducting quantum dots - more fancifully dubbed artificial atoms - are quasi-zero dimensional, tiny, man-made systems with charge carriers completely confined in all three dimensions. The scientific quest behind the synthesis of quantum dots is to create and control future electronic and optical nanostructures engineered through tailoring size, shape, and composition. The complete confinement - or the lack of any degree of freedom for the electrons (and/or holes) - in quantum dots limits the exploration of spatially localized elementary excitations such as plasmons to direct rather than reciprocal space. Here we embark on a thorough investigation of the magneto-optical absorption in semiconducting spherical quantum dots characterized by a confining harmonic potential and an applied magnetic field in the symmetric gauge. This is done within the framework of Bohm-Pines' random-phase approximation that enables us to derive and discuss the full Dyson equation that takes proper account of the Coulomb interactions. As an application of our theoretical strategy, we compute various single-particle and many-particle phenomena such as the Fock-Darwin spectrum; Fermi energy; magneto-optical transitions; probability distribution; and the magneto-optical absorption in the quantum dots. It is observed that the role of an applied magnetic field on the absorption spectrum is comparable to that of a confining potential. Increasing (decreasing) the strength of the magnetic field or the confining potential is found to be analogous to shrinking (expanding) the size of the quantum dots: resulting into a blue (red) shift in the absorption spectrum. The Fermi energy diminishes with both increasing magnetic-field and dot-size; and exhibits saw-tooth-like oscillations at large values of field or dot-size. Unlike laterally confined quantum dots, both (upper and lower) magneto-optical transitions survive even in the extreme instances. However, the intra-Landau level transitions are seen

  10. Magneto-optical absorption in semiconducting spherical quantum dots: Influence of the dot-size, confining potential, and magnetic field

    SciTech Connect

    Kushwaha, Manvir S.

    2014-12-15

    Semiconducting quantum dots – more fancifully dubbed artificial atoms – are quasi-zero dimensional, tiny, man-made systems with charge carriers completely confined in all three dimensions. The scientific quest behind the synthesis of quantum dots is to create and control future electronic and optical nanostructures engineered through tailoring size, shape, and composition. The complete confinement – or the lack of any degree of freedom for the electrons (and/or holes) – in quantum dots limits the exploration of spatially localized elementary excitations such as plasmons to direct rather than reciprocal space. Here we embark on a thorough investigation of the magneto-optical absorption in semiconducting spherical quantum dots characterized by a confining harmonic potential and an applied magnetic field in the symmetric gauge. This is done within the framework of Bohm-Pines’ random-phase approximation that enables us to derive and discuss the full Dyson equation that takes proper account of the Coulomb interactions. As an application of our theoretical strategy, we compute various single-particle and many-particle phenomena such as the Fock-Darwin spectrum; Fermi energy; magneto-optical transitions; probability distribution; and the magneto-optical absorption in the quantum dots. It is observed that the role of an applied magnetic field on the absorption spectrum is comparable to that of a confining potential. Increasing (decreasing) the strength of the magnetic field or the confining potential is found to be analogous to shrinking (expanding) the size of the quantum dots: resulting into a blue (red) shift in the absorption spectrum. The Fermi energy diminishes with both increasing magnetic-field and dot-size; and exhibits saw-tooth-like oscillations at large values of field or dot-size. Unlike laterally confined quantum dots, both (upper and lower) magneto-optical transitions survive even in the extreme instances. However, the intra-Landau level

  11. Nuclear data evaluation of long-lived fission products: Microscopic vs. phenomenological optical potentials

    NASA Astrophysics Data System (ADS)

    Minato, Futoshi; Iwamoto, Osamu; Minomo, Kosho; Ogata, Kazuyuki; Iwamoto, Nobuyuki; Kunieda, Satoshi; Furutachi, Naoya

    2017-09-01

    Neutron-nucleus cross sections calculated by macroscopic potentials are compared with a microscopic one to study the performance for long-lived fission products. The macroscopic potentials show a good agreement with the microscopic one at higher energies, where neutron experimental data are scarce. Besides it, analyses of differential elastic cross sections at low energies also suggest that the macroscopic potentials are still effective and applicable enough for the long-lived fission products.

  12. EVALUATION OF OPTICALLY ACQUIRED ZOOPLANKTON SIZE-SPECTRUM DATA AS A POTENTIAL TOOL FOR ASSESSMENT OF CONDITION IN THE GREAT LAKES

    EPA Science Inventory

    An optical zooplankton counter (OPC) potentially provides as assessment tool for zooplankton condition in ecosystems that is rapid, economical, and spatially extensive. We collected zooplankton data with an optical zooplankton counter in 20 near-shore regions of four of the Laure...

  13. Low-Coherence Interferometric Fiber-Optic Sensors with Potential Applications as Biosensors

    PubMed Central

    Hirsch, Marzena; Majchrowicz, Daria; Wierzba, Paweł; Weber, Matthieu; Bechelany, Mikhael; Jędrzejewska-Szczerska, Małgorzata

    2017-01-01

    Fiber-optic Fabry-Pérot interferometers (FPI) can be applied as optical sensors, and excellent measurement sensitivity can be obtained by fine-tuning the interferometer design. In this work, we evaluate the ability of selected dielectric thin films to optimize the reflectivity of the Fabry-Pérot cavity. The spectral reflectance and transmittance of dielectric films made of titanium dioxide (TiO2) and aluminum oxide (Al2O3) with thicknesses from 30 to 220 nm have been evaluated numerically and compared. TiO2 films were found to be the most promising candidates for the tuning of FPI reflectivity. In order to verify and illustrate the results of modelling, TiO2 films with the thickness of 80 nm have been deposited on the tip of a single-mode optical fiber by atomic layer deposition (ALD). The thickness, the structure, and the chemical properties of the films have been determined. The ability of the selected TiO2 films to modify the reflectivity of the Fabry-Pérot cavity, to provide protection of the fibers from aggressive environments, and to create multi-cavity interferometric sensors in FPI has then been studied. The presented sensor exhibits an ability to measure refractive index in the range close to that of silica glass fiber, where sensors without reflective films do not work, as was demonstrated by the measurement of the refractive index of benzene. This opens up the prospects of applying the investigated sensor in biosensing, which we confirmed by measuring the refractive index of hemoglobin and glucose. PMID:28134855

  14. Low-Coherence Interferometric Fiber-Optic Sensors with Potential Applications as Biosensors.

    PubMed

    Hirsch, Marzena; Majchrowicz, Daria; Wierzba, Paweł; Weber, Matthieu; Bechelany, Mikhael; Jędrzejewska-Szczerska, Małgorzata

    2017-01-28

    Fiber-optic Fabry-Pérot interferometers (FPI) can be applied as optical sensors, and excellent measurement sensitivity can be obtained by fine-tuning the interferometer design. In this work, we evaluate the ability of selected dielectric thin films to optimize the reflectivity of the Fabry-Pérot cavity. The spectral reflectance and transmittance of dielectric films made of titanium dioxide (TiO₂) and aluminum oxide (Al₂O₃) with thicknesses from 30 to 220 nm have been evaluated numerically and compared. TiO₂ films were found to be the most promising candidates for the tuning of FPI reflectivity. In order to verify and illustrate the results of modelling, TiO₂ films with the thickness of 80 nm have been deposited on the tip of a single-mode optical fiber by atomic layer deposition (ALD). The thickness, the structure, and the chemical properties of the films have been determined. The ability of the selected TiO₂ films to modify the reflectivity of the Fabry-Pérot cavity, to provide protection of the fibers from aggressive environments, and to create multi-cavity interferometric sensors in FPI has then been studied. The presented sensor exhibits an ability to measure refractive index in the range close to that of silica glass fiber, where sensors without reflective films do not work, as was demonstrated by the measurement of the refractive index of benzene. This opens up the prospects of applying the investigated sensor in biosensing, which we confirmed by measuring the refractive index of hemoglobin and glucose.

  15. Potential for use of optical measurements to understand the fate of urban contaminants

    NASA Astrophysics Data System (ADS)

    Bergamaschi, B. A.; Downing, B. D.; Fleck, J.; Kraus, T. E.; Pellerin, B. A.; Corsi, S. R.

    2012-12-01

    Contamination associated with urban environments can dramatically affect aquatic ecosystems, yet our ability to gage its impact is hampered by the fact that contamination occurs episodically and we are often most interested in the effects in highly dynamic environments; ephemeral and dynamic systems require large numbers of samples to monitor, and the cost associated with characterizing the contribution of urban contaminants in an individual sample using conventional tracers can be prohibitively expensive. We propose that optical measurements may be used to help characterize urban contaminant fluxes in dynamic systems using in situ instruments as well as to assess the contribution of urban material to individual water samples using inexpensive lab-based measurements. We have used measurements of optical properties both in the laboratory and in situ at high temporal and spatial resolution to differentiate among sources of water, and as proxies for contaminants such as mercury (Hg), methylmercury, pharmaceuticals, and wastewater. These measurements include determination of spectral properties of absorbance, attenuation, fluorescence, and scatter in aqueous samples. We present examples of how such measurements can serve as tracers of urban-derived water sources, and provide information about source and biogeochemical processing. One example demonstrates how in situ fluorescence and scattering measurements were used to track the transport of Hg contamination into the San Francisco Estuary. We measured the tidally-driven exchange of Hg between the estuary and a tidal wetland over spring-neap in three different seasons. In situ measurements of scatter (turbidity) and fluorescent dissolved organic matter (FDOM) were highly related to total mercury concentrations, and we used these measurements to calculate flux into and out of the wetland. Another example in a dynamic river system illustrates how data collected at a high spatial resolution, again using in situ optical

  16. Potential of optical coherence tomography for early diagnosis of oral malignancies

    PubMed Central

    DeCoro, Michael; Wilder-Smith, Petra

    2014-01-01

    With nearly 1,500,000 new patients diagnosed every year in the USA, cancer poses a considerable challenge to healthcare today. Oral cancer is responsible for a sizeable portion of deaths due to cancer, primarily because it is diagnosed at a late stage when the prognosis is poor. Current methods for diagnosing oral cancer need to be augmented by better early detection, monitoring and screening modalities. A new approach is needed that provides real-time, accurate, noninvasive diagnosis. The results of early clinical trials using in vivo optical coherence tomography for the diagnosis of oral dysplasia and malignancy are encouraging. PMID:20214513

  17. Potential of Brillouin scattering in polymer optical fiber for strain-insensitive high-accuracy temperature sensing.

    PubMed

    Mizuno, Yosuke; Nakamura, Kentaro

    2010-12-01

    We investigated the dependences of Brillouin frequency shift (BFS) on strain and temperature in a perfluorinated graded-index polymer optical fiber (PFGI-POF) at 1.55 μm wavelength. They showed negative dependences with coefficients of -121.8 MHz/% and -4.09 MHz/K, respectively, which are -0.2 and -3.5 times as large as those in silica fibers. These unique BFS dependences indicate that the Brillouin scattering in PFGI-POFs has a big potential for strain-insensitive high-accuracy temperature sensing.

  18. Optical Model Potentials for {alpha}-Particles Scattering around the Coulomb Barrier on Medium-Mass Nuclei

    SciTech Connect

    Avrigeanu, M.; Roman, F.L.; Avrigeanu, V.

    2005-05-24

    Following a semi-microscopic and phenomenological analyses of {alpha}-particle elastic scattering on A{approx}100 nuclei at energies below 32 MeV, a regional optical potential is involved in (n,{alpha}) reaction cross-sections analysis for the stable Mo isotopes. Focus on the uncertainties in the OMP parameters found to describe the {alpha}-particle emission from excited compound residual nuclei is thus obtained, looking for understanding of the related questions on the basis of microscopic models.

  19. Spectral imaging as a potential tool for optical sentinel lymph node biopsies

    NASA Astrophysics Data System (ADS)

    O'Sullivan, Jack D.; Hoy, Paul R.; Rutt, Harvey N.

    2011-07-01

    Sentinel Lymph Node Biopsy (SLNB) is an increasingly standard procedure to help oncologists accurately stage cancers. It is performed as an alternative to full axillary lymph node dissection in breast cancer patients, reducing the risk of longterm health problems associated with lymph node removal. Intraoperative analysis is currently performed using touchprint cytology, which can introduce significant delay into the procedure. Spectral imaging is forming a multi-plane image where reflected intensities from a number of spectral bands are recorded at each pixel in the spatial plane. We investigate the possibility of using spectral imaging to assess sentinel lymph nodes of breast cancer patients with a view to eventually developing an optical technique that could significantly reduce the time required to perform this procedure. We investigate previously reported spectra of normal and metastatic tissue in the visible and near infrared region, using them as the basis of dummy spectral images. We analyse these images using the spectral angle map (SAM), a tool routinely used in other fields where spectral imaging is prevalent. We simulate random noise in these images in order to determine whether the SAM can discriminate between normal and metastatic pixels as the quality of the images deteriorates. We show that even in cases where noise levels are up to 20% of the maximum signal, the spectral angle map can distinguish healthy pixels from metastatic. We believe that this makes spectral imaging a good candidate for further study in the development of an optical SLNB.

  20. Temperature dependent optical characterization of Ni-TiO2 thin films as potential photocatalytic material

    NASA Astrophysics Data System (ADS)

    De, Rajnarayan; Haque, S. Maidul; Tripathi, S.; Rao, K. Divakar; Singh, Ranveer; Som, T.; Sahoo, N. K.

    2017-09-01

    Along with other transition metal doped titanium dioxide materials, Ni-TiO2 is considered to be one of the most efficient materials for catalytic applications due to its suitable energy band positions in the electronic structure. The present manuscript explores the possibility of improving the photocatalytic activity of RF magnetron sputtered Ni-TiO2 films upon heat treatment. Optical, structural and morphological and photocatalytic properties of the films have been investigated in detail for as deposited and heat treated samples. Evolution of refractive index (RI) and total film thickness as estimated from spectroscopic ellipsometry characterization are found to be in agreement with the trend in density and total film thickness estimated from grazing incidence X-ray reflectivity measurement. Interestingly, the evolution of these macroscopic properties were found to be correlated with the corresponding microstructural modifications realized in terms of anatase to rutile phase transformation and appearance of a secondary phase namely NiTiO3 at high temperature. Corresponding morphological properties of the films were also found to be temperature dependent which leads to modifications in the grain structure. An appreciable reduction of optical band gap from 2.9 to 2.5 eV of Ni-TiO2 thin films was also observed as a result of post deposition heat treatment. Testing of photocatalytic activity of the films performed under UV illumination demonstrates heat treatment under atmospheric ambience to be an effective means to enhance the photocatalytic efficiency of transition metal doped titania samples.

  1. Determination of the optical properties of vascular tissues: potential applications in vascular-targeting photodynamic therapy

    NASA Astrophysics Data System (ADS)

    Tian, Yongbin; Chen, Ping; Lin, Lie; Huang, Zheng; Tang, Guoqing; Xu, Heping

    2007-11-01

    It has been proven that photodynamic therapy (PDT) is effective in treating various malignant and non-malignant diseases. In the treatment of certain non-malignant vascular diseases, such as wet age-related macular degeneration (AMD) and port wine stains (PWS), unlike in the treatment of malignant solid tumors, light irradiation usually starts immediately after the intravenous (IV) injection of photosensitizers while the photosensitizers is mainly circulating inside blood vessels. Under such vascular-targeting action mode, photoreactions between photosensitizers and light can selectively destruct the vascular tissues. Light distribution is complex so that it is important to understand the optical properties of targeted vessels and surrounding tissues. To better determine the optical properties of vascular tissues, we developed a tissue-simulating phantom and adopted frequency-domain measurement of phase difference. Absorption and reduced scattering coefficients in blood vessels were estimated and light distribution was simulated by the Monte Carlo method. These determinations are essential for the implication of better light dosimetry models in clinical photodynamic therapy and vascular-targeting PDT, in particular.

  2. Optical Constants of the Ammonium Ion: A Potential Ice Product in the Outer Solar System

    NASA Astrophysics Data System (ADS)

    Roush, T. L.; Moore, M. H.; Cook, J. C.

    2008-12-01

    Optical constants, the real and imaginary indices of refraction, are the fundamental values used in a wide variety of radiative transfer models that are relevant to many environments including circumstellar disks, planetary atmospheres, and planetary surfaces. Cook et al. (2007) observed a feature near 2.2 micrometers (um) in the reflectance spectrum of Pluto's moon, Charon. They suggested evidence for both ammonia di- hydrate and ammonia hemi-hydrate on opposite hemispheres of Charon. Moore et al. (2003) discuss the irradiation of N2-CH4-CO ices; mixtures relevant for Pluto, Triton, and a plausible constituent for some Kuiper Belt Objects and Centaurs. One stable product observed after irradiation of the ice mixture is the ammonium ion, NH4+. NH4+ has strong spectral features in the 3-4 um region and weaker overtones near 2.21 and 2.24 um (Moore et al. 2003). The 2.21 um feature is the strongest of the overtone bands and is near the wavelengths observed for Charon. Using the measurements of Moore et al. (2003) the optical constants of NH4+ are estimated and will be available to investigate NH4+ as an alternative candidate for the feature observed on Charon. Moore, M. et al. 2003, Earth Moon Planets, 92, 291-306. Cook, J. et al. 2007, Ap J, 663, 1406-1419.

  3. Potential of vortex beams with orbital angular momentum modulation for deep-space optical communication

    NASA Astrophysics Data System (ADS)

    Wang, Xiaorui; Liu, Yejun; Guo, Lei; Li, Hui

    2014-05-01

    In order to achieve multigigabit transmission in deep-space optical communication, our study applies a new modulation mode named orbital angular momentum (OAM) modulation, and uses the encoded OAM states of single photon as data information carriers, thus providing a reliable and high-speed transmission of signals. According to the long link characteristic of deep-space communication, we conduct a reasonable deployment for communication nodes in deep-space environment. First, we present the reliability of deep-space channel and analyze the data rate and spectral efficiency of beams with OAM. Second, we study the characteristics and generations of vortex beams with OAM by simulation. Results show that vortex beams have better spatial multiplexing capability of realizing high capacity data transmission. Finally, we propose an encoding method with OAM states of single photon. The transceiver units are based on spatial light modulators to perform the modulation and demodulation of vortex beams. At the receiver, the charged-coupled device camera is used to detect the signal intensity and decodes the OAM states. Our proposal not only ensures the confidentiality of deep-space optical communication, but also greatly increases the transmission rate.

  4. Time-variable gravity potential components for optical clock comparisons and the definition of international time scales

    NASA Astrophysics Data System (ADS)

    Voigt, C.; Denker, H.; Timmen, L.

    2016-12-01

    The latest generation of optical atomic clocks is approaching the level of one part in 1018 in terms of frequency stability and uncertainty. For clock comparisons and the definition of international time scales, a relativistic redshift effect of the clock frequencies has to be taken into account at a corresponding uncertainty level of about 0.1 m2 s-2 and 0.01 m in terms of gravity potential and height, respectively. Besides the predominant static part of the gravity potential, temporal variations must be considered in order to avoid systematic frequency shifts. Time-variable gravity potential components induced by tides and non-tidal mass redistributions are investigated with regard to the level of one part in 1018. The magnitudes and dominant time periods of the individual gravity potential contributions are investigated globally and for specific laboratory sites together with the related uncertainty estimates. The basics of the computation methods are presented along with the applied models, data sets and software. Solid Earth tides contribute by far the most dominant signal with a global maximum amplitude of 4.2 m2 s-2 for the potential and a range (maximum-to-minimum) of up to 1.3 and 10.0 m2 s-2 in terms of potential differences between specific laboratories over continental and intercontinental scales, respectively. Amplitudes of the ocean tidal loading potential can amount up to 1.25 m2 s-2, while the range of the potential between specific laboratories is 0.3 and 1.1 m2 s-2 over continental and intercontinental scales, respectively. These are the only two contributors being relevant at a 10-17 level. However, several other time-variable potential effects can particularly affect clock comparisons at the 10-18 level. Besides solid Earth pole tides, these are non-tidal mass redistributions in the atmosphere, the oceans and the continental water storage.

  5. Determination of the real part of the η'-Nb optical potential

    NASA Astrophysics Data System (ADS)

    Nanova, M.; Friedrich, S.; Metag, V.; Paryev, E. Ya.; Afzal, F. N.; Bayadilov, D.; Beck, R.; Becker, M.; Böse, S.; Brinkmann, K.-T.; Crede, V.; Elsner, D.; Frommberger, F.; Grüner, M.; Gutz, E.; Hammann, Ch.; Hannappel, J.; Hartmann, J.; Hillert, W.; Hoffmeister, P.; Honisch, Ch.; Jude, T.; Kalischewski, F.; Keshelashvili, I.; Klein, F.; Koop, K.; Krusche, B.; Lang, M.; Makonyi, K.; Messi, F.; Müller, J.; Müllers, J.; Piontek, D.-M.; Rostomyan, T.; Schaab, D.; Schmidt, C.; Schmieden, H.; Schmitz, R.; Seifen, T.; Sowa, C.; Spieker, K.; Thiel, A.; Thoma, U.; Triffterer, T.; Urban, M.; van Pee, H.; Walther, D.; Wendel, C.; Werthmüller, D.; Wiedner, U.; Wilson, A.; Witthauer, L.; Wunderlich, Y.; Zaunick, H.-G.; Cbelsa/Taps Collaboration

    2016-08-01

    The excitation function and momentum distribution of η' mesons have been measured in photoproduction off 93Nb in the energy range of 1.2-2.9 GeV. The experiment has been performed with the combined Crystal Barrel and MiniTAPS detector system, using tagged photon beams from the ELSA electron accelerator. Information on the sign and magnitude of the real part of the η'-Nb potential has been extracted from a comparison of the data with model calculations. An attractive potential of -(41 ±10 (stat )±15 (syst )) MeV depth at normal nuclear matter density is deduced within model uncertainties. This value is consistent with the potential depth of -(37 ±10 (stat )±10 (syst )) MeV obtained in an earlier measurement for a light nucleus (carbon). This relatively shallow η'-nucleus potential will make the search for η'-nucleus bound states more difficult.

  6. Successful Nd:Yag Laser Photocoagulation Of Arrhythmogenic Myocardium: Potential Limitations Of Current Optical Delivery Systems.

    NASA Astrophysics Data System (ADS)

    Svenson, Robert H.; Marroum, Marie-Claire; Frank, Frank; Selle, Jay G.; Gallagher, John J.; Bou-Saba, George; Seifert, Kathleen T.; Linder, Kathy; Tatsis, George P.

    1987-04-01

    Canine myocardial lesions of predictable dimensions can be achieved with Nd:YAG laser photocoagulation. These lesions are well demarcated from surrounding normal tissue and heal with homogeneous scar formation. Intraoperative Nd:YAG laser photocoagulation successfully ablated 52 of 55 ventricular tachycardias in 17 patients. Histologic examination of tissues from these arrhythmogenic areas showed differences from lesions produced on canine epicardium. Lesions from the human cases were less predictable and not well circumscribed. These differences are felt to be due to optical inhomogeneities present in diseased, scarred human myocardium, geometric irregularities of the endocardial surface, anatomical constraints on tissue-fiber distance, and the angle of incidence of the beam with the tissue. Modifications of current delivery systems may overcome some of these limitations. Ablation of ventricular tachycardia arising deeper than 4.0 to 6.0 mm. from the irradiated surface may require interstitial probes coupled to the fiberoptic.

  7. Strong electron spin-Hall effect by a coherent optical potential

    NASA Astrophysics Data System (ADS)

    Sherman, E. Ya; Muga, J. G.; Dugaev, V. K.; Ruschhaupt, A.

    2010-09-01

    We demonstrate theoretically that a coherent manipulation of electron spins in low-dimensional semiconductor structures with a spin-orbit coupling by infrared radiation is possible. The proposed approach is based on using a dipole force acting on a two-level system in a nonuniform optical field, similar to that employed in the design of the cold atoms diode. For ballistic electrons the spin-dependent force, proportional to the intensity of external radiation, leads to a spin-Hall effect and the resulting spin separation even if the spin-orbit coupling itself does not allow for these effects. Achievable spatial separation of electrons with opposite spins can be of the order of several tenths of a micron; an order of magnitude larger than that can be produced by the charged impurity scattering in the diffusive regime.

  8. Dysprosium complexes and their micelles as potential bimodal agents for magnetic resonance and optical imaging.

    PubMed

    Debroye, Elke; Laurent, Sophie; Vander Elst, Luce; Muller, Robert N; Parac-Vogt, Tatjana N

    2013-11-18

    Six diethylene triamine pentaacetic acid (DTPA) bisamide derivatives functionalized with p-toluidine (DTPA-BTolA), 6-aminocoumarin (DTPA-BCoumA), 1-naphthalene methylamine (DTPA-BNaphA), 4-ethynylaniline (DTPA-BEthA), p-dodecylaniline (DTPA-BC12PheA) and p-tetradecyl-aniline (DTPA-BC14PheA) were coordinated to dysprosium(III) and the magnetic and optical properties of the complexes were examined in detail. The complexes consisting of amphiphilic ligands (DTPA-BC12PheA and DTPA-BC14PheA) were further assembled into mixed micelles. Upon excitation into the ligand levels, the complexes display characteristic Dy(III) emission with quantum yields of 0.3-0.5% despite the presence of one water molecule in the first coordination sphere. A deeper insight into the energy-transfer processes has been obtained by studying the photophysical properties of the corresponding Gd(III) complexes. Since the luminescence quenching effect is decreased by the intervention of non-ionic surfactant, quantum yields up to 1% are obtained for the micelles. The transverse relaxivity r2 per Dy(III) ion at 500 MHz and 310 K reaches a maximum value of 27.4 s(-1) mM(-1) for Dy-DTPA-BEthA and 36.0 s(-1) mM(-1) for the Dy-DTPA-BC12PheA assemblies compared with a value of 0.8 s(-1) mM(-1) for Dy-DTPA. The efficient T2 relaxation, especially at high magnetic field strengths, is sustained by the high magnetic moment of the dysprosium ion, the coordination of water molecules with slow water exchange kinetics and long rotational correlation times. These findings open the way to the further development of bimodal optical and magnetic resonance imaging probes starting from single lanthanide compounds.

  9. Trends in aerosol optical depth over Indian region: Potential causes and impact indicators

    NASA Astrophysics Data System (ADS)

    Babu, S. Suresh; Manoj, M. R.; Moorthy, K. Krishna; Gogoi, Mukunda M.; Nair, Vijayakumar S.; Kompalli, Sobhan Kumar; Satheesh, S. K.; Niranjan, K.; Ramagopal, K.; Bhuyan, P. K.; Singh, Darshan

    2013-10-01

    first regional synthesis of long-term (back to ~ 25 years at some stations) primary data (from direct measurement) on aerosol optical depth from the ARFINET (network of aerosol observatories established under the Aerosol Radiative Forcing over India (ARFI) project of Indian Space Research Organization over Indian subcontinent) have revealed a statistically significant increasing trend with a significant seasonal variability. Examining the current values of turbidity coefficients with those reported ~ 50 years ago reveals the phenomenal nature of the increase in aerosol loading. Seasonally, the rate of increase is consistently high during the dry months (December to March) over the entire region whereas the trends are rather inconsistent and weak during the premonsoon (April to May) and summer monsoon period (June to September). The trends in the spectral variation of aerosol optical depth (AOD) reveal the significance of anthropogenic activities on the increasing trend in AOD. Examining these with climate variables such as seasonal and regional rainfall, it is seen that the dry season depicts a decreasing trend in the total number of rainy days over the Indian region. The insignificant trend in AOD observed over the Indo-Gangetic Plain, a regional hot spot of aerosols, during the premonsoon and summer monsoon season is mainly attributed to the competing effects of dust transport and wet removal of aerosols by the monsoon rain. Contributions of different aerosol chemical species to the total dust, simulated using Goddard Chemistry Aerosol Radiation and Transport model over the ARFINET stations, showed an increasing trend for all the anthropogenic components and a decreasing trend for dust, consistent with the inference deduced from trend in Angstrom exponent.

  10. Characterizing the potential of MEMS deformable mirrors for astronomical adaptive optics

    NASA Astrophysics Data System (ADS)

    Morzinski, Katie M.; Evans, Julia W.; Severson, Scott; Macintosh, Bruce; Dillon, Daren; Gavel, Don; Max, Claire; Palmer, Dave

    2006-06-01

    Current high-contrast "extreme" adaptive optics (ExAO) systems are partially limited by deformable mirror technology. Mirror requirements specify thousands of actuators, all of which must be functional within the clear aperture, and which give nanometer flatness yet micron stroke when operated in closed loop.1 Micro-electrical mechanical-systems (MEMS) deformable mirrors have been shown to meet ExAO actuator yield, wavefront error, and cost considerations. This study presents the performance of Boston Micromachines' 1024-actuator continuous-facesheet MEMS deformable mirrors under tests for actuator stability, position repeatability, and practical operating stroke. To explore whether MEMS actuators are susceptible to temporal variation, a series of long-term stability experiments were conducted. Each actuator was held fixed and the motion over 40 minutes was measured. The median displacement of all the actuators tested was 0.08 nm surface, inclusive of system error. MEMS devices are also appealing for adaptive optics architectures based on open-loop correction. In experiments of actuator position repeatability, 100% of the tested actuators returned repeatedly to their starting point with a precision of < 1 nm surface. Finally, MEMS devices were tested for maximum stroke achieved under application of spatially varying one-dimensional sinusoids. Given a specified amplitude in voltage, the measured stroke was 1 μm surface at the low spatial frequencies, decreasing to 0.2 μm surface for the highest spatial frequency. Stroke varied somewhat linearly as inverse spatial frequency, with a flattening in the relation at the high spatial frequency end.

  11. Optical imaging for the diagnosis of oral cancer and oral potentially malignant disorders

    NASA Astrophysics Data System (ADS)

    Yoshida, K.

    2016-03-01

    Optical Imaging is being conducted as a therapeutic non-invasive. Many kinds of the light source are selected for this purpose. Recently the oral cancer screening is conducted by using light-induced tissue autofluorescence examination such as several kinds of handheld devices. However, the mechanism of its action is still not clear. Therefore basic experimental research was conducted. One of auto fluorescence Imaging (AFI) device, VELscopeTM and near-infrared (NIR) fluorescence imaging using ICG-labeled antibody as a probe were compared using oral squamous cell carcinoma (OSCC) mouse models. The experiments revealed that intracutaneous tumor was successfully visualized as low density image by VELscopeTM and high density image by NIR image. In addition, VELscopeTM showed higher sensitivity and lower specificity than that of NIR fluorescence imaging and the sensitivity of identification of carcinoma areas with the VELscopeTM was good results. However, further more studies were needed to enhance the screening and diagnostic uses, sensitivity and specificity for detecting malignant lesions and differentiation from premalignant or benign lesions. Therefore, additional studies were conducted using a new developed near infrared (NIR) fluorescence imaging method targeting podoplanine (PDPN) which consists of indocyanine green (ICG)-labeled anti-human podoplanin antibody as a probe and IVIS imaging system or a handy realtime ICG imaging device that is overexpressed in oral malignant neoplasm to improve imaging for detection of early oral malignant neoplasm. Then evaluated for its sensitivity and specificity for detection of oral malignant neoplasm in xenografted mice model and compared with VELscopeTM. The results revealed that ICG fluorescence imaging method and VELscopeTM had the almost the same sensitivity for detection of oral malignant neoplasm. The current topics of optical imaging about oral malignant neoplasm were reviewed.

  12. Microscopic optical model potential based on a Dirac Brueckner Hartree Fock approach and the relevant uncertainty analysis

    NASA Astrophysics Data System (ADS)

    Xu, Ruirui; Ma, Zhongyu; Muether, Herbert; van Dalen, E. N. E.; Liu, Tinjin; Zhang, Yue; Zhang, Zhi; Tian, Yuan

    2017-09-01

    A relativistic microscopic optical model potential, named CTOM, for nucleon-nucleus scattering is investigated in the framework of Dirac-Brueckner-Hartree-Fock approach. The microscopic feature of CTOM is guaranteed through rigorously adopting the isospin dependent DBHF calculation within the subtracted T matrix scheme. In order to verify its prediction power, a global study n, p+ A scattering are carried out. The predicted scattering observables coincide with experimental data within a good accuracy over a broad range of targets and a large region of energies only with two free items, namely the free-range factor t in the applied improved local density approximation and minor adjustments of the scalar and vector potentials in the low-density region. In addition, to estimate the uncertainty of the theoretical results, the deterministic simple least square approach is preliminarily employed to derive the covariance of predicted angular distributions, which is also briefly contained in this paper.

  13. Stark-potential evaporative cooling of polar molecules in a novel optical-access opened electrostatic trap

    NASA Astrophysics Data System (ADS)

    Sun, Hui; Wang, Zhen-Xia; Wang, Qin; Li, Xing-Jia; Liu, Jian-Ping; Yin, Jian-Ping

    2015-11-01

    We propose a novel optical-access opened electrostatic trap to study the Stark-potential evaporative cooling of polar molecules by using two charged disk electrodes with a central hole of radius r0 =1.5 mm, and derive a set of new analytical equations to calculate the spatial distributions of the electrostatic field in the above charged-disk layout. Afterwards, we calculate the electric-field distributions of our electrostatic trap and the Stark potential for cold ND3 molecules, and analyze the dependences of both the electric field and the Stark potential on the geometric parameters of our charged-disk scheme, and find an optimal condition to form a desirable trap with the same trap depth in the x, y, and z directions. Also, we propose a desirable scheme to realize an efficient loading of cold polar molecules in the weak-field-seeking states, and investigate the dependences of the loading efficiency on both the initial forward velocity of the incident molecular beam and the loading time by Monte Carlo simulations. Our study shows that the maximal loading efficiency of our trap scheme can reach about 95%, and the corresponding temperature of the trapped cold molecules is about 28.8 mK. Finally, we study the Stark-potential evaporative cooling for cold polar molecules in our trap by the Monte Carlo method, and find that our simulated evaporative cooling results are consistent with our developed analytical model based on trapping-potential evaporative cooling.

  14. Energy dependence of the optical potentials for the 9Be +208Pb and 9Be +209Bi systems at near-Coulomb-barrier energies

    NASA Astrophysics Data System (ADS)

    Gómez Camacho, A.; Yu, N.; Zhang, H. Q.; Gomes, P. R. S.; Jia, H. M.; Lubian, J.; Lin, C. J.

    2015-04-01

    We analyze the energy dependence of the interacting optical potential, at near barrier energies, for two systems involving the weakly bound projectile 9Be and the heavy 208Pb and 209Bi targets, by the simultaneous fit of elastic scattering angular distributions and fusion excitation functions. The approach used consists of dividing the optical potential into two parts. A short-range potential VF+i WF that is responsible for fusion, and a superficial potential VDR+i WDR for direct reactions. It is found, for both systems studied, that the fusion imaginary potential WF presents the usual threshold anomaly (TA) observed in tightly bound systems, whereas the direct reaction imaginary potential WDR shows a breakup threshold anomaly (BTA) behavior. Both potentials satisfy the dispersion relation. The direct reaction polarization potential predominates over the fusion potential and so a net overall behavior is found to follow the BTA phenomenon.

  15. A non-iterative treatment of the non-local exchange terms in the Complex Optical Potential method

    NASA Astrophysics Data System (ADS)

    Stauffer, Allan; McEachran, Robert

    2016-09-01

    Non-local exchange terms in atomic scattering equations are usually treated iteratively. This method normally works well but there can be problems with convergence, either requiring a large number of iterations or converging to a spurious value. It has long been known that these terms can be treated non-iteratively but at the cost of expanding the number of equations needed to be solved. With the vastly increased memory and speed of modern computers, this approach is now feasible even for heavier targets. We have decided to implement this method in our calculations of electron elastic scattering from atoms using the Complex Optical Potential (COP) method which is based on the relativistic Dirac equations. This method accounts for incident flux lost to the elastic channels through inelastic processes (excitation and ionization) via the imaginary part of the optical potential and also provides a value for the total cross section for these processes. The basis for the method will be given along with sample calculations where the iterative method fails.

  16. Ventricular filling slows epicardial conduction and increases action potential duration in an optical mapping study of the isolated rabbit heart

    NASA Technical Reports Server (NTRS)

    Sung, Derrick; Mills, Robert W.; Schettler, Jan; Narayan, Sanjiv M.; Omens, Jeffrey H.; McCulloch, Andrew D.; McCullough, A. D. (Principal Investigator)

    2003-01-01

    INTRODUCTION: Mechanical stimulation can induce electrophysiologic changes in cardiac myocytes, but how mechanoelectric feedback in the intact heart affects action potential propagation remains unclear. METHODS AND RESULTS: Changes in action potential propagation and repolarization with increased left ventricular end-diastolic pressure from 0 to 30 mmHg were investigated using optical mapping in isolated perfused rabbit hearts. With respect to 0 mmHg, epicardial strain at 30 mmHg in the anterior left ventricle averaged 0.040 +/- 0.004 in the muscle fiber direction and 0.032 +/- 0.006 in the cross-fiber direction. An increase in ventricular loading increased average epicardial activation time by 25%+/- 3% (P < 0.0001) and correspondingly decreased average apparent surface conduction velocity by 16%+/- 7% (P = 0.007). Ventricular loading did not significantly alter action potential duration at 20% repolarization (APD20) but did at 80% repolarization (APD80), from 179 +/- 7 msec to 207 +/- 5 msec (P < 0.0001). The dispersion of APD20 was decreased with loading from 19 +/- 2 msec to 13 +/- 2 msec (P = 0.024), whereas the dispersion of APD80 was not significantly changed. These electrophysiologic changes with ventricular loading were not affected by the nonspecific stretch-activated channel blocker streptomycin (200 microM) and were not attributable to changes in myocardial perfusion or the presence of an electromechanical decoupling agent (butanedione monoxime) during optical mapping. CONCLUSION: Acute loading of the left ventricle of the isolated rabbit heart decreased apparent epicardial conduction velocity and increased action potential duration by a load-dependent mechanism that may not involve stretch-activated channels.

  17. Ventricular filling slows epicardial conduction and increases action potential duration in an optical mapping study of the isolated rabbit heart

    NASA Technical Reports Server (NTRS)

    Sung, Derrick; Mills, Robert W.; Schettler, Jan; Narayan, Sanjiv M.; Omens, Jeffrey H.; McCulloch, Andrew D.; McCullough, A. D. (Principal Investigator)

    2003-01-01

    INTRODUCTION: Mechanical stimulation can induce electrophysiologic changes in cardiac myocytes, but how mechanoelectric feedback in the intact heart affects action potential propagation remains unclear. METHODS AND RESULTS: Changes in action potential propagation and repolarization with increased left ventricular end-diastolic pressure from 0 to 30 mmHg were investigated using optical mapping in isolated perfused rabbit hearts. With respect to 0 mmHg, epicardial strain at 30 mmHg in the anterior left ventricle averaged 0.040 +/- 0.004 in the muscle fiber direction and 0.032 +/- 0.006 in the cross-fiber direction. An increase in ventricular loading increased average epicardial activation time by 25%+/- 3% (P < 0.0001) and correspondingly decreased average apparent surface conduction velocity by 16%+/- 7% (P = 0.007). Ventricular loading did not significantly alter action potential duration at 20% repolarization (APD20) but did at 80% repolarization (APD80), from 179 +/- 7 msec to 207 +/- 5 msec (P < 0.0001). The dispersion of APD20 was decreased with loading from 19 +/- 2 msec to 13 +/- 2 msec (P = 0.024), whereas the dispersion of APD80 was not significantly changed. These electrophysiologic changes with ventricular loading were not affected by the nonspecific stretch-activated channel blocker streptomycin (200 microM) and were not attributable to changes in myocardial perfusion or the presence of an electromechanical decoupling agent (butanedione monoxime) during optical mapping. CONCLUSION: Acute loading of the left ventricle of the isolated rabbit heart decreased apparent epicardial conduction velocity and increased action potential duration by a load-dependent mechanism that may not involve stretch-activated channels.

  18. Optical magnetic detection of single-neuron action potentials using NV-diamond

    NASA Astrophysics Data System (ADS)

    Turner, Matthew; Barry, John; Schloss, Jennifer; Glenn, David; Walsworth, Ron

    2016-05-01

    A key challenge for neuroscience is noninvasive, label-free sensing of action potential dynamics in whole organisms with single-neuron resolution. Here, we report a new approach to this problem: using nitrogen-vacancy (NV) color centers in diamond to measure the time-dependent magnetic fields produced by single-neuron action potentials. We demonstrate our method using excised single neurons from two invertebrate species, marine worm and squid; and then by single-neuron action potential magnetic sensing exterior to whole, live, opaque marine worms for extended periods with no adverse effect. The results lay the groundwork for real-time, noninvasive 3D magnetic mapping of functional mammalian neuronal networks.

  19. Global analysis of isospin dependent microscopic nucleon-nucleus optical potentials in a Dirac-Brueckner-Hartree-Fock approach

    NASA Astrophysics Data System (ADS)

    Xu, Ruirui; Ma, Zhongyu; Zhang, Yue; Tian, Yuan; van Dalen, E. N. E.; Müther, H.

    2016-09-01

    Background: For the study of exotic nuclei it is important to have an optical model potential that is reliable not only for stable nuclei but can also be extrapolated to nuclear systems with exotic numbers of protons and neutrons. An efficient way to obtain such a potential is to develop a microscopic optical potential (MOP) based on a fundamental theory with a minimal number of free parameters, which are adjusted to describe stable nuclei all over the nuclide chart. Purpose: The choice adopted in the present work is to develop the MOP within a relativistic scheme which provides a natural and consistent relation between the spin-orbit part and the central part of the potential. The Dirac-Brueckner-Hartree-Fock (DBHF) approach provides such a microscopic relativistic scheme, which is based on a realistic nucleon-nucleon interaction and reproduces the saturation properties of symmetric nuclear matter without any adjustable parameter. Its solution using the projection technique within the subtracted T -matrix representation provides a reliable extension to asymmetric nuclear matter, which is important to describe the features of isospin asymmetric nuclei. The present work performs a global analysis of the isospin dependent nucleon-nucleus MOP based on the DBHF calculation in symmetric and asymmetric nuclear matter. Methods: The DBHF approach is used to evaluate the relativistic structure of the nucleon self-energies in nuclear matter at various densities and asymmetries. The Schrödinger equivalent potentials of finite nuclei are derived from these Dirac components by a local density approximation (LDA). The density distributions of finite nuclei are taken from the Hartree-Fock-Bogoliubov approach with Gogny D1S force. An improved LDA approach (ILDA) is employed to get a better prediction of the scattering observables. A χ2 assessment system based on the global simulated annealing algorithm is developed to optimize the very few free components in this study. Results

  20. Optical imaging of cell membrane potential changes induced by applied electric fields.

    PubMed Central

    Gross, D; Loew, L M; Webb, W W

    1986-01-01

    We report the first imaging of the spatial distributions of transmembrane potential changes induced in nonexcitable cells by applied external electric fields. These changes are indicated by the fluorescence intensity of a charge-shift potentiometric dye incorporated in the cell plasma membrane and measured by digital intensified video microscopy. Images FIGURE 2 FIGURE 3 FIGURE 5 FIGURE 7 PMID:3741986

  1. Role of modified Becke-Johnson potential in computation of electronic and optical properties of mixed crystals CdxZn1-xSe

    NASA Astrophysics Data System (ADS)

    Talreja, Sonal; Ahuja, B. L.

    2015-08-01

    Electronic and optical properties of CdxZn1-xSe (x = 0, 0.25, 0.5, 0.75, 1) compounds are investigated using the first-principles full potential linearized augmented plane wave method. In particular, we have used modified version of the exchange potential of Becke and Johnson, so called mBJ potential. We have discussed the energy bands, density of states, and optical properties such as dielectric constants, refractive indices, reflection spectra, extinction coefficients of all the CdxZn1-xSe compounds. Our mBJ potential based data are found to be in excellent agreement with the available experimental data, which unambiguously validates the applicability of orbital independent exchange-correlation potential in mixed semiconductor crystals. The optical properties are discussed in terms of applicability of Cd-Zn-Se system in light-emitting diodes, UV detectors and filters, etc.

  2. Potential Measurement Errors Due to Image Enlargement in Optical Coherence Tomography Imaging

    PubMed Central

    Uji, Akihito; Murakami, Tomoaki; Muraoka, Yuki; Hosoda, Yoshikatsu; Yoshitake, Shin; Dodo, Yoko; Arichika, Shigeta; Yoshimura, Nagahisa

    2015-01-01

    The effect of interpolation and super-resolution (SR) algorithms on quantitative and qualitative assessments of enlarged optical coherence tomography (OCT) images was investigated in this report. Spectral-domain OCT images from 30 eyes in 30 consecutive patients with diabetic macular edema (DME) and 20 healthy eyes in 20 consecutive volunteers were analyzed. Original image (OR) resolution was reduced by a factor of four. Images were then magnified by a factor of four with and without application of one of the following algorithms: bilinear (BL), bicubic (BC), Lanczos3 (LA), and SR. Differences in peak signal-to-noise ratio (PSNR), retinal nerve fiber layer (RNFL) thickness, photoreceptor layer status, and parallelism (reflects the complexity of photoreceptor layer alterations) were analyzed in each image type. The order of PSNRs from highest to lowest was SR > LA > BC > BL > non-processed enlarged images (NONE). The PSNR was statistically different in all groups. The NONE, BC, and LA images resulted in significantly thicker RNFL measurements than the OR image. In eyes with DME, the photoreceptor layer, which was hardly identifiable in NONE images, became detectable with algorithm application. However, OCT photoreceptor parameters were still assessed as more undetectable than in OR images. Parallelism was not statistically different in OR and NONE images, but other image groups had significantly higher parallelism than OR images. Our results indicated that interpolation and SR algorithms increased OCT image resolution. However, qualitative and quantitative assessments were influenced by algorithm use. Additionally, each algorithm affected the assessments differently. PMID:26024236

  3. Potential application of pure silica optical flat fibers for radiation therapy dosimetry

    NASA Astrophysics Data System (ADS)

    Alawiah, A.; Bauk, S.; Abdul-Rashid, H. A.; Gieszczyk, W.; Hashim, S.; Mahdiraji, G. A.; Tamchek, N.; Bradley, D. A.

    2015-01-01

    Pure silica optical flat fibers (FF) have been proposed as the basis for a novel radiation sensor by the measurement of the thermoluminescence (TL) produced. In this paper the TL performance of the FFs were studied. Using a linear accelerator (LINAC) delivering doses in the range 0.2-10.0 Gy, the TL dosimetric glow curves of the FFs were studied with respect to 6 MeV electron and 6 MV photon beams. When exposed to 6 MeV electron irradiation, the pure silica FFs displayed a supralinear response starting from 2 Gy up to 10.0 Gy. While for 6 MV photon irradiation, the FFs shows linear characteristic (f(D)=1) nearly up to 2 Gy. The TL intensity (Im) of the main peak of FFs is 1.5 times higher for 6 MeV electron beams than for 6 MV photon beams. The maximum peak temperature (Tm) it is not affected by the type of irradiation used at the same dose while the maximum TL intensity (Im) was found to be dependent on the type of radiation used. Overall results indicate that the pure silica FFs can be used as radiation sensors in the high-dose therapy dosimetry.

  4. Dental optical coherence tomography: new potential diagnostic system for cracked-tooth syndrome.

    PubMed

    Lee, Sang-Hee; Lee, Jong-Jin; Chung, Hyun-Jin; Park, Jong-Tae; Kim, Hee-Jin

    2016-01-01

    The aim of the present study was to determine the reliability of optical coherence tomography (OCT) in detecting cracked teeth and its relative clinical effectiveness by comparing it with other diagnostic methods including conventional visual inspection, trans-illumination, and micro-computed tomography (micro-CT). The reliability of swept source OCT (SS-OCT) was verified by comparing the number of detected crack lines on 109 surfaces of 61 teeth with those detected with other conventional methods. One to one comparison revealed that crack lines that were invisible with naked eyes could be found in SS-OCT images. The detection ability of SS-OCT was superior or similar to those of micro-CT (100.0 %) and trans-illumination. Crack lines shown in the SS-OCT images had distinct characteristics, and structural crack lines and craze lines could be distinguished in SS-OCT images. Thus, the detection ability of SS-OCT renders it an acceptable diagnostic device for cracked-tooth syndrome.

  5. Reducing multisensor monthly mean aerosol optical depth uncertainty: 2. Optimal locations for potential ground observation deployments

    NASA Astrophysics Data System (ADS)

    Li, Jing; Li, Xichen; Carlson, Barbara E.; Kahn, Ralph A.; Lacis, Andrew A.; Dubovik, Oleg; Nakajima, Teruyuki

    2017-04-01

    Surface remote sensing of aerosol properties provides "ground truth" for satellite and model validation and is an important component of aerosol observation system. Due to the different characteristics of background aerosol variability, information obtained at different locations usually has different spatial representativeness, implying that the location should be carefully chosen so that its measurement could be extended to a greater area. In this study, we present an objective observation array design technique that automatically determines the optimal locations with the highest spatial representativeness based on the Ensemble Kalman Filter (EnKF) theory. The ensemble is constructed using aerosol optical depth (AOD) products from five satellite sensors. The optimal locations are solved sequentially by minimizing the total analysis error variance, which means that observations at these locations will reduce the background error variance to the largest extent. The location determined by the algorithm is further verified to have larger spatial representativeness than some other arbitrary location. In addition to the existing active Aerosol Robotic Network (AERONET) sites, the 40 selected optimal locations are mostly concentrated on regions with both high AOD inhomogeneity and its spatial representativeness, namely, the Sahel, South Africa, East Asia, and North Pacific Islands. These places should be the focuses of establishing future AERONET sites in order to further reduce the uncertainty in the monthly mean AOD. Observations at these locations contribute to approximately 50% of the total background uncertainty reduction.

  6. Potential aluminium(III)- and gallium(III)-selective optical sensors based on porphyrazines.

    PubMed

    Goslinski, Tomasz; Tykarska, Ewa; Kryjewski, Michal; Osmalek, Tomasz; Sobiak, Stanislaw; Gdaniec, Maria; Dutkiewicz, Zbigniew; Mielcarek, Jadwiga

    2011-01-01

    Porphyrazines possessing non-coordinating alkyl (propyl) and aralkyl (4-tert-butylphenyl) groups in the periphery were studied as optical sensors for a set of mono-, di- and trivalent cations. Investigated porphyrazines in the UV-Vis monitored titrations revealed significant responses towards aluminium and gallium cations, unlike other metal ions studied. Additionally, porphyrazine possessing 4-tert-butylphenyl peripheral substituents showed sensor property towards ruthenium cation and was chosen for further investigation. The presence of isosbestic points in absorption spectra for its titration with aluminium, gallium and ruthenium cations, accompanied by a linear Benesi-Hildebrand plot, proved complex formation. The continuous variation method was used to determine binding stoichiometry in 1:1 porphyrazine-metal ratio. X-Ray studies and density functional theory calculations were employed to investigate octa(4-tert-butylphenyl)porphyrazine structure. The results helped to explain the observed selectivity towards certain ions. Interaction between ion and porphyrazine meso nitrogen in a Lewis acid-Lewis base manner is proposed.

  7. Imaging of skin microvessels with optical coherence tomography: potential uses in port wine stains

    PubMed Central

    ZHOU, YANG; YIN, DAIQIANG; XUE, PING; HUANG, NAIYAN; QIU, HAIXIA; WANG, YING; ZENG, JING; DING, ZHIHUA; GU, YING

    2012-01-01

    The knowledge of vascular structures of port wine stains (PWSs) may be useful to select treatment doses and improve therapeutic efficacy. Biopsies are impractical to implement, therefore, it is necessary to develop non-invasive techniques for morphological evaluation. This study aimed to evaluate the application of a novel optical coherence tomography (OCT) system to characterize the vascular structures of PWSs. First, OCT images were obtained from the skin of healthy rabbit ears and compared with the histopathological images. Second, OCT was used to document the differences between PWS lesions and contralateral normal skin; the size and depth of the vascular structures of two clinical types of PWSs were measured and statistically analyzed. The dermal blood vessels of healthy rabbit ears were clearly distinguished from other tissue. There was no statistical difference between the vascular diameter or depth measured by OCT images and histopathological sections (P>0.05). The OCT images of the PWSs could be distinguished from normal skin. There was no statistical difference in the depth of vessels between the purple-type and the proliferative-type PWSs (P>0.05), while there was statistical difference in the diameter of vessels between them (P<0.01). Therefore, OCT is a promising, real-time, in vivo and non-invasive tool with which to characterize the vascular structures of PWSs. PMID:23226766

  8. Dispersive coupled-channels optical-model potential with soft-rotator couplings for Cr, Fe, and Ni isotopes

    NASA Astrophysics Data System (ADS)

    Li, Rui; Sun, Weili; Soukhovitskiĩ, E. Sh.; Quesada, J. M.; Capote, R.

    2013-05-01

    An approximate Lane-consistent dispersive coupled-channels optical potential is derived that describes nucleon-induced reactions on even iron isotopes. Realistic saturated couplings for 54,56,58Fe nuclei are built using nuclear wave functions of the soft-rotator model with the Hamiltonian parameters adjusted to reproduce the energy of the low-lying collective levels of these isotopes. E2- and E3-transition probabilities between low-lying collective levels are well reproduced. The comprehensive experimental database used in the fitting process includes all scattering data for neutron and proton scattering up to 200 MeV on iron nuclei. The derived potential is shown to be applicable to Ni and Cr isotopes, assuming the applicability of the soft-rotator model to these nuclei and to the odd 57Fe nucleus within the rigid-rotor model. The approximate Lane consistency of the derived potential is validated by describing the quasielastic (p,n) scattering with excitation of isobaric analog states. Elastic and inelastic analyzing powers for both neutron- and proton-induced reactions are shown to be in good agreement with experimental data, demonstrating the reliability of the derived dispersive spin-orbit potential.

  9. A Fully Lane-consistent Dispersive Optical Model Potential for Even Fe Isotopes Based on a Soft-rotator Model

    NASA Astrophysics Data System (ADS)

    Sun, W.; Li, R.; Soukhovitskiı˜, E. Sh.; Quesada, J. M.; Capote, R.

    2014-04-01

    A fully Lane-consistent dispersive coupled-channel optical model (DCCOM) potential is derived that describes nucleon induced reactions on even iron isotopes. Low-lying structure of excited levels in iron even-even isotopes is described by a soft-rotator model that allows for dynamical deformation around the spherical shape. Soft-rotator Hamiltonian parameters are adjusted to reproduce the experimental energies of the low-lying collective levels of these isotopes. The comprehensive experimental database used in the fitting process included all scattering data for neutron and proton scattering up to 200 MeV. Employed Lane-consistent formalism allows deriving a potential fully symmetric for neutrons and protons. Lane consistency of the derived potential was validated by describing the quasi-elastic (p,n) scattering with excitation of IAS states. An exact approach for calculation of inelastic analyzing powers is derived. Calculated elastic and inelastic analyzing powers both for neutron and proton induced reactions were shown to be in good agreement with experimental data demonstrating the reliability of dispersive spin-orbit potential.

  10. Latency delay of visual evoked potential is a real measurement of demyelination in a rat model of optic neuritis.

    PubMed

    You, Yuyi; Klistorner, Alexander; Thie, Johnson; Graham, Stuart L

    2011-08-29

    To investigate the relationship between size of demyelinated lesion, extent of axonal loss, and degree of latency delay of visual evoked potentials (VEPs) in a rat model of experimental demyelination. Lysolecithin 1% (0.4 or 0.8 μL) was microinjected into an optic nerve of each of 14 rats 2 mm posterior to the globe. Standard flash VEPs were recorded with skull-implanted electrodes before and 2, 4, and 6 days after the microinjection. The optic nerves were stained with Luxol-fast blue and Bielschowsky's silver to assess demyelination and axonal pathology, respectively. Demyelinated areas were measured on serial sections, and lesion volumes were deduced by three-dimensional reconstruction. Focal lesions of demyelination and variable axonal loss were observed. The mean volume of the lesion was 3.2 ± 1.1 × 10⁻² mm³. The injected eye showed a significant latency delay and amplitude decrease. Regression analysis demonstrated a strong correlation between N1 latency delay and lesion volume (r = 0.863, P < 0.0001), which remained significant after adjustment for axonal loss (r = 0.829, P < 0.001). N1 latency delay also showed a correlation with axonal loss (r = 0.552, P = 0.041), but the correlation became nonsignificant when controlling for demyelination (r = 0.387, P = 0.191). A linear association between N1-P2 amplitude decrease and axonal loss (r = 0.681, P = 0.007) was also observed. The latency of the VEP accurately reflected the amount of demyelination in the visual pathway, whereas the amplitude correlated with axonal damage. This study supports the concept that the VEP provides a highly sensitive tool with which to measure demyelination in optic neuritis.

  11. The study of visual evoked potentials in patients with thyroid-associated ophthalmopathy identifies asymptomatic optic nerve involvement.

    PubMed

    Salvi, M; Spaggiari, E; Neri, F; Macaluso, C; Gardini, E; Ferrozzi, F; Minelli, R; Wall, J R; Roti, E

    1997-04-01

    In the present study we have recorded visual evoked cortical potentials (VECP) in 88 patients affected by autoimmune thyroid disease and thyroid-associated ophthalmopathy (TAO) without clinical signs of optic neuropathy. At the time of ophthalmological examination, 37 of these patients were hyperthyroid, 41 were euthyroid, and 8 were hypothyroid; 2 were not assessed. Twenty-nine normal subjects served as controls. We performed pattern reversal visual stimulation and recorded the amplitude and latency of the cortical electric response at 100 ms (P100 wave). There were no differences in the mean P100 amplitude of TAO patients and normal subjects. The mean P100 latency in patients was 105.6 +/- 0.5 ms, significantly higher than that in normal subjects (102.0 +/- 0.5 ms; P < 0.00003). Latency in euthyroid patients did not differ from that in either hypo- or hyperthyroid patients. The VECP test was positive (latency, > or = 110.0 ms) in 21 (23.8%) TAO patients. In patients with proptosis greater than 21 mm, latency was 106.7 +/- 0.7 ms, significantly higher than that in patients with normal Hertel measurements (104.3 +/- 0.6 ms; P < 0.01). Latency was not increased in patients with acute inflammatory signs compared to those with inactive eye disease and in patients with altered extrinsic motility. In patients with an abnormal visual field study, the mean latency was 110.3 +/- 1.5 ms, significantly higher than that in patients with a normal visual field (104.7 +/- 0.4; by t test, P < 0.000003). In conclusion, we observed a prolongation of the latency of the evoked cortical response in patients with TAO without subjective visual complaints and without optic nerve compression. We believe that the study of VECP in TAO is complementary to the study of the visual field in identifying early optic nerve dysfunction in the absence of decreased visual acuity.

  12. Optical and grain boundary potential characteristics of sulfurized BiFeO3 thin films for photovoltaic applications.

    PubMed

    Lee, Seung Min; Cho, Yong Soo

    2016-04-07

    Sulfurized BiFeO3 (BFO) thin films have been investigated with the purpose of reducing their band gap for photovoltaic applications. A strong dependence of the degree of sulfurization on the structure and optical properties of the BFO thin films was observed. The sulfurization process substantially reduced the optical band gap from 2.83 eV for the reference sample to ∼1.90 eV in a sample sulfurized at 200 °C, a temperature at which the BFO phase was still dominant. The existence of the secondary Bi2S3 phase was found to be initiated from the film surface and became dominant at higher temperatures. XPS analysis suggests potential Bi-Fe(iii)-Fe(ii)-S-O compounds as a result of the change of the oxidation state of Fe with the progress of sulfurization. The sulfurized BFO film exhibited relatively higher positively charged grain boundaries than the reference film, suggesting its improved applicability in photovoltaic devices.

  13. 20Hz membrane potential oscillations are driven by synaptic inputs in collision-detecting neurons in the frog optic tectum.

    PubMed

    Baranauskas, Gytis; Svirskiene, Natasa; Svirskis, Gytis

    2012-10-24

    Although the firing patterns of collision-detecting neurons have been described in detail in several species, the mechanisms generating responses in these neurons to visual objects on a collision course remain largely unknown. This is partly due to the limited number of intracellular recordings from such neurons, particularly in vertebrate species. By employing patch recordings in a novel integrated frog eye-tectum preparation we tested the hypothesis that OFF retinal ganglion cells were driving the responses to visual objects on a collision course in the frog optic tectum neurons. We found that the majority (22/26) of neurons in layer 6 responding to visual stimuli fitted the definition of η class collision-detectors: they readily responded to a looming stimulus imitating collision but not a receding stimulus (spike count difference ∼10 times) and the spike firing rate peaked after the stimulus visual angle reached a threshold value of ∼20-45°. In the majority of these neurons (15/22) a slow frequency oscillation (f=∼20Hz) of the neuronal membrane potential could be detected in the responses to a simulated collision stimulus, as well as to turning off the lights. Since OFF retinal ganglion cells could produce such oscillations, our observations are in agreement with the hypothesis that 'collision' responses in the frog optic tectum neurons are driven by synaptic inputs from OFF retinal ganglion cells. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  14. Dispersive optical-model potential for protons in 100 ⩽ A ⩽ 132 even–even tin isotopes

    SciTech Connect

    Bespalova, O. V. Romanovsky, E. A.; Spasskaya, T. I.; Klimochkina, A. A.

    2015-10-15

    Data on single-particle energies, differential elastic-scattering cross sections, and total cross sections for proton-induced reactions on stable tin isotopes were analyzed on the basis of the dispersive optical model. Good agreement with experimental data was obtained by setting the parameters of the dispersive optical potential to values averaged over the tin isotopic chain and by assuming that the dependence of surface absorption on the neutron–proton asymmetry is close to a traditional dependence. Predictive calculations for single-particle proton spectra and total reaction cross sections were performed for the doubly magic isotopes {sup 100,132}Sn. The calculated values of the energy gap between the 1h{sub 11/2}–1g{sub 7/2} and 1g{sub 7/2}–2d{sub 5/2} states were found to be in good agreement with the results of calculations performed with allowance for the tensor component of the effective nucleon–nucleon interaction.

  15. Fibre Optic Laser Doppler Anemometry, The Potential For Measurements In Man.

    NASA Astrophysics Data System (ADS)

    Kilpatrick, Walker D.

    1984-10-01

    Fibre optic laser Doppler anemometry (FOLDA) is a useful technique for in vitro studies but has yet to be used successfully for the measurement of intravascular velocity in man. Some reasons for this are: 1. The difficulty of locating the position of the fibre within the vessel. 2. Lack of knowledge of the precise velocity profile across the vessel. 3. The effects of flow perturbation at the tip of the probe. These problems have been assessed using a FOLDA system developed in our laboratory. Three dimensional velocity profiles of blood flowing in arteries with and without stenoses have been plotted at different rates of flow. The results show that the parabolic profile of fully developed laminar flow is flattened in an arterial stenosis and the degree of flattening increases as flow increases. This means the relationship of the flow and velocity is nonlinear. Any use of FOLDA to assess vessel dimension must take this into account. The position of the fibre in the vessel can only be adequately controlled in in-vitro studies. The region of measurement is only 50 μm diameter and must be at the position of the peak velocity to enable quantitative measurement. Thus the technique is useful in humans only when there is a flat velocity profile such as in the coronary sinus. The relationship between coronary sinus flow and FOLDA velocity is linear in experimental animals. The current FOLDA system has a limited range of projection into the blood stream. The velocity is not linearly related to blood flow when the direction of flow is the same as the projected light, probably due to flow perturbation at the fibre tip. This means that a probe introduced into a coronary artey would not measure linear flow however a probe introduced against the flow could be used to assess the severity of peripheral arterial stenoses. To measure flow across a stenoses before and after angioplasty is possible but requires a method of obtaining an average spatial velocity before it is practicable.

  16. Dynamical instability of a Bose-Einstein condensate with higher-order interactions in an optical potential through a variational approach.

    PubMed

    Wamba, E; Sabari, S; Porsezian, K; Mohamadou, A; Kofané, T C

    2014-05-01

    We investigate the dynamical instability of Bose-Einstein condensates (BECs) with higher-order interactions immersed in an optical lattice with weak driving harmonic potential. For this, we compute both analytically and numerically a modified Gross-Pitaevskii equation with higher-order nonlinearity and external potentials generated by magnetic and optical fields. Using the time-dependent variational approach, we derive the ordinary differential equations for the time evolution of the amplitude and phase of modulational perturbation. Through an effective potential, we obtain the modulational instability condition of BECs and discuss the effect of the higher-order interaction in the dynamics of the condensates in presence of optical potential. We perform direct numerical simulations to support our analytical results, and good agreement is found.

  17. Potential of optical microangiography to monitor cerebral blood perfusion and vascular plasticity following traumatic brain injury in mice in vivo

    NASA Astrophysics Data System (ADS)

    Jia, Yali; Alkayed, Nabil; Wang, Ruikang K.

    2009-07-01

    Optical microanglography (OMAG) is a recently developed imaging modality capable of volumetric imaging of dynamic blood perfusion, down to capillary level resolution, with an imaging depth up to 2.00 mm beneath the tissue surface. We report the use of OMAG to monitor the cerebral blood flow (CBF) over the cortex of mouse brain upon traumatic brain injury (TBI), with the cranium left intact, for a period of two weeks on the same animal. We show the ability of OMAG to repeatedly image 3-D cerebral vasculatures during pre- and post-traumatic phases, and to visualize the changes of regulated CBF and the vascular plasticity after TBI. The results indicate the potential of OMAG to explore the mechanism involved in the rehabilitation of TBI.

  18. Detection of Neural Action Potentials Using Optical Coherence Tomography: Intensity and Phase Measurements with and without Dyes

    PubMed Central

    Akkin, Taner; Landowne, David; Sivaprakasam, Aarthi

    2010-01-01

    We review the use of optical coherence tomography (OCT) for detection of neural activity, and present a new approach for depth-localization of neural action potentials (APs) using voltage-sensitive dyes as contrast agents in OCT. A stained squid giant axon is imaged by spectral-domain OCT. Changes in the intensity and phase of back-scattered light coming from regions around the membrane are measured during AP propagation. The depth-resolved change in back-scattered intensity coincides with the arrival of AP at the measurement area, and is synchronous with the changes in transmitted light intensity and reflection-mode cross-polarized light intensity measured independently. The system also provides depth-resolved phase changes as an additional indication of activity. With further investigation our results could open a new era in functional imaging technology to localize neural activity at different depths in situ. PMID:20844600

  19. Constraints on the α + nucleus optical-model potential via α-induced reaction studies on 108Cd

    NASA Astrophysics Data System (ADS)

    Scholz, P.; Heim, F.; Mayer, J.; Münker, C.; Netterdon, L.; Wombacher, F.; Zilges, A.

    2016-10-01

    A big part in understanding the nucleosynthesis of heavy nuclei is a proper description of the effective interaction between an α-particle and a target nucleus. Information about the so-called α +nucleus optical-model potential is achieved by precise cross-section measurements at sub-Coulomb energies aiming to constrain the theoretical models for the nuclear physics input-parameters. The cross sections of the 108Cd(α , γ) and 108Cd(α , n) reaction have been measured for the first time close to the astrophysically relevant energy region via the in-beam method at the high-efficiency γ-ray spectrometer HORUS and via the activation technique at the Cologne Clover Counting Setup at the Institute for Nuclear Physics in Cologne, Germany. Comparisons between experimental results and theoretical predictions calculated in the scope of the Hauser-Feshbach statistical model confirm the need for a exponentially decreasing imaginary part of the potential. Moreover, it is shown that the results presented here together with already published data indicate that a systematic investigation of the real part of the potential could help to further improve the understanding of reactions involving α-particles.

  20. A dispersive optical model potential for nucleon induced reactions on 238U and 232Th nuclei with full coupling

    NASA Astrophysics Data System (ADS)

    Quesada, José Manuel; Soukhovitskiĩ, EfremS.; Capote, Roberto; Chiba, Satoshi

    2013-03-01

    A dispersive coupled-channel optical model potential (DCCOMP) that couples the ground-state rotational and low-lying vibrational bands of 238U and 232Th nuclei is studied. The derived DCCOMP couples almost all excited levels below 1 MeV of excitation energy of the corresponding even-even actinides. The ground state, octupole, beta, gamma, and non-axial bands are coupled. The first two isobar analogue states (IAS) populated in the quasi-elastic (p,n) reaction are also coupled in the proton induced calculation, making the potential approximately Lane consistent. The coupled-channel potential is based on a soft-rotor description of the target nucleus structure, where dynamic vibrations are considered as perturbations of the rigid rotor underlying structure. Matrix elements required to use the proposed structure model in Tamura coupled-channel scheme are derived. Calculated ratio R(U238/Th232) of the total cross-section difference to the averaged σT for 238U and 232Th nuclei is shown to be in excellent agreement with measured data.

  1. The effects of a geometrical size, external electric fields and impurity on the optical gain of a quantum dot laser with a semi-parabolic spherical well potential

    NASA Astrophysics Data System (ADS)

    Owji, Erfan; Keshavarz, Alireza; Mokhtari, Hosein

    2017-03-01

    In this paper, a GaAs / Alx Ga1-x As quantum dot laser with a semi-parabolic spherical well potential is assumed. By using Runge-Kutta method the eigenenergies and the eigenstates of valence and conduct bands are obtained. The effects of geometrical sizes, external electric fields and hydrogen impurity on the different electronic transitions of the optical gain are studied. The results show that the optical gain peak increases and red-shifts, by increasing the width of well or barrier, while more increasing of the width causes blue-shift and decreases it. The hydrogen impurity decreases the optical gain peak and blue-shifts it. Also, the increasing of the external electric fields cause to increase the peak of the optical gain, and (blue) red shift it. Finally, the optical gain for 1s-1s and 2s-1s transitions is prominent, while it is so weak for other transitions.

  2. Perspectives, potentials and trends of ex vivo and in vivo optical molecular pathology.

    PubMed

    Krafft, Christoph; von Eggeling, Ferdinand; Guntinas-Lichius, Orlando; Hartmann, Arndt; Waldner, Maximilian J; Neurath, Markus F; Popp, Jürgen

    2017-10-03

    It is pivotal for medical applications, such as non-invasive histopathologic characterization of tissue, to realize label-free and molecule-specific representation of morphologic and biochemical composition in real-time with subcellular spatial resolution. This unmet clinical need requires new approaches for rapid and reliable real-time assessment of pathologies to complement established diagnostic tools. Photonic imaging combined with digitalization offers the potential to provide the clinician the requested information both under in vivo and ex vivo conditions. This report summarizes photonic approaches and their use in combination with image processing, machine learning and augmented virtual reality might to solve current challenges in modern medicine. Details are given for pathology, intraoperative diagnosis in head and neck cancer and endoscopic diagnosis in gastroenterology. Multimodal image of a colon section combining CARS, SHG and TPEF for label-free contrast of the crypt structure. This article is protected by copyright. All rights reserved.

  3. Simulating heavy fermion physics in optical lattice: Periodic Anderson model with harmonic trapping potential

    NASA Astrophysics Data System (ADS)

    Zhong, Yin; Liu, Yu; Luo, Hong-Gang

    2017-10-01

    The periodic Anderson model (PAM), where local electron orbitals interplay with itinerant electronic carriers, plays an essential role in our understanding of heavy fermion materials. Motivated by recent proposals for simulating the Kondo lattice model (KLM) in terms of alkaline-earth metal atoms, we take another step toward the simulation of PAM, which includes the crucial charge/valence fluctuation of local f-electrons beyond purely low-energy spin fluctuation in the KLM. To realize PAM, a transition induced by a suitable laser between the electronic excited and ground state of alkaline-earth metal atoms (1 S 0⇌3 P 0) is introduced. This leads to effective hybridization between local electrons and conduction electrons in PAM. Generally, the SU( N) version of PAM can be realized by our proposal, which gives a unique opportunity to detect large- N physics without complexity in realistic materials. In the present work, high-temperature physical features of standard [ SU(2)] PAM with harmonic trapping potential are analyzed by quantum Monte Carlo and dynamic mean-field theory, where the Mott/orbital-selective Mott state was found to coexist with metallic states. Indications for near-future experiments are provided. We expect our theoretical proposal and (hopefully) forthcoming experiments will deepen our understanding of heavy fermion systems. At the same time, we hope these will trigger further studies on related Mott physics, quantum criticality, and non-trivial topology in both the inhomogeneous and nonequilibrium realms.

  4. Diagnostic potential of optical coherence tomography in non-melanoma skin cancer: a clinical study

    NASA Astrophysics Data System (ADS)

    Mogensen, Mette; Thrane, Lars; Jørgensen, Thomas Martini; Jemec, Gregor B. E.

    2007-07-01

    Introduction: Non-melanoma skin cancer (NMSC) is the most prevalent cancer in the Western World. OCT has proved potential in assisting clinical diagnosis and perhaps reducing the need for biopsies in NMSC. As non-invasive treatment is increasingly used for NMSC patients with superficial lesions, the development of non-invasive diagnostic technologies is highly relevant. Methods: The aim of this cross-sectional clinical study, enrolling 100 NMSC patients and 20 healthy volunteers, is to investigate the diagnostic accuracy and applicability of OCT in NMSC diagnosis. Our OCT-system has been developed at Risoe National Laboratory, Denmark and offers ppolarization sensitive-OCT (PS-OCT) that may have additional advantaged as NMSC differ in content of birefringent collagens from normal skin. Results: Basal cell carcinomas (BCC) can in some cases be distinguished from normal skin in OCT-images, as normal skin exhibits a layered structure this layering is not present in BCC and sometimes not in actinic keratosis (AK). BCC lesions seem to be clearly less reflective than normal tissue. The predictive value of OCT in NMSC will be presented from a clinical point of view. Discussion: The earlier a skin cancer is diagnosed, the better the prognosis. Estimation of diagnostic accuracy and abilities of OCT in clinical studies of skin cancer patients is essential to establish the role and future set-ups for diagnostic OCT-systems.

  5. Non-linear optical deformation potentials in uniaxially strained ZnO microwires

    NASA Astrophysics Data System (ADS)

    Sturm, C.; Wille, M.; Lenzner, J.; Khujanov, S.; Grundmann, M.

    2017-02-01

    The emission properties of bent ZnO microwires with diameters ranging from 1.5 μm to 7.3 μm are systematically investigated by cathodoluminescence spectroscopy at T ≈ 10 K . We induced uniaxial strains along the c-axis of up to ± 2.9 % . At these high strain values, we observe a non-linear shift of the emission energy with respect to the induced strain, and the magnitude of the energy shift depends on the sign of the strain. The linear and non-linear deformation potentials were determined to be D 1 = - 2.50 ± 0.05 eV and D 2 = - 15.0 ± 0.5 eV , respectively. The non-linearity of the energy shift is also reflected in the observed spectral broadening of the emission peak as a function of the locally induced strain, which decreases with increasing strain on the compressive side and increases on the tensile side.

  6. Towards Quantitative Optical Cross Sections in Entomological Laser Radar – Potential of Temporal and Spherical Parameterizations for Identifying Atmospheric Fauna

    PubMed Central

    Brydegaard, Mikkel

    2015-01-01

    In recent years, the field of remote sensing of birds and insects in the atmosphere (the aerial fauna) has advanced considerably, and modern electro-optic methods now allow the assessment of the abundance and fluxes of pests and beneficials on a landscape scale. These techniques have the potential to significantly increase our understanding of, and ability to quantify and manage, the ecological environment. This paper presents a concept whereby laser radar observations of atmospheric fauna can be parameterized and table values for absolute cross sections can be catalogued to allow for the study of focal species such as disease vectors and pests. Wing-beat oscillations are parameterized with a discrete set of harmonics and the spherical scatter function is parameterized by a reduced set of symmetrical spherical harmonics. A first order spherical model for insect scatter is presented and supported experimentally, showing angular dependence of wing beat harmonic content. The presented method promises to give insights into the flight heading directions of species in the atmosphere and has the potential to shed light onto the km-range spread of pests and disease vectors. PMID:26295706

  7. Diagnostic potential of multimodal imaging of ovarian tissue using optical coherence tomography and second-harmonic generation microscopy.

    PubMed

    Welge, Weston A; DeMarco, Andrew T; Watson, Jennifer M; Rice, Photini S; Barton, Jennifer K; Kupinski, Matthew A

    2014-07-18

    Ovarian cancer is particularly deadly because it is usually diagnosed after it has metastasized. We have previously identified features of ovarian cancer using optical coherence tomography (OCT) and second-harmonic generation (SHG) microscopy (targeting collagen). OCT provides an image of the ovarian microstructure while SHG provides a high-resolution map of collagen fiber bundle arrangement. Here we investigated the diagnostic potential of dual-modality OCT and SHG imaging. We conducted a fully crossed, multi-reader, multi-case study using seven human observers. Each observer classified 44 ex vivo mouse ovaries (16 normal and 28 abnormal) as normal or abnormal from OCT, SHG, and simultaneously viewed, co-registered OCT and SHG images and provided a confidence rating on a six-point scale. We determined the average receiver operating characteristic (ROC) curves, area under the ROC curves (AUC), and other quantitative figures of merit. The results show that OCT has diagnostic potential with an average AUC of 0.91 ± 0.06. The average AUC for SHG was less promising at 0.71 ± 0.13. The average AUC for simultaneous OCT and SHG was not significantly different from OCT alone, possibly due to the limited SHG field of view. The high performance of OCT and co-registered OCT and SHG warrants further investigation.

  8. Investigation of the potential of optical coherence tomography (OCT) as a non-invasive diagnostic tool in reproductive medicine

    NASA Astrophysics Data System (ADS)

    Trottmann, Matthias; Homann, Christian; Leeb, R.; Doering, D.; Kuznetsova, J.; Reese, S.; Stief, C. G.; Koelle, S.; Sroka, R.

    2015-02-01

    Introduction and objective: In Europe, nearly every sixth couple in the reproductive age is involuntarily childless. In about 30%, both male and female reveal fertility problems. In about 10% of infertile men, azoospermia is the underlying cause. As conventional therapeutic options are limited, surgical testicular sperm extraction (TESE) is necessary to obtain sperms for assisted reproductive techniques. Regarding the females, up to 30% of all idiopathic infertilities are due to alterations of the uterine tube So far, no imaging technique, which does not require any labelling, is available to evaluate the male and female genital tract at a microscopic level under in vivo conditions. Thus, the aim of this study was to investigate the potential of optical coherence tomography (OCT) as a non-invasive diagnostic tool in gynaecology and andrology. Material and Methods: Tissues samples from the bovine testis, epididymis, vas deferens, ovary, oviduct (ampulla and isthmus) and uterus were obtained immediately after slaughter (14 cows aged 3 to 8 years and 14 bulls aged 3 to 6 years; breeds: Holstein- Friesian, and Deutsches Fleckvieh). Imaging was done by using the US Food and Drug Administration (FDA) approved probe-based Niris Imaging System (Imalux, Cleveland, Ohio, USA) and the Telesto 1325 nm OCT System and Ganymede 930 nm OCT System (Thorlabs Inc., Dachau, Germany). All images obtained were compared to histological images after paraffin embedding and HE staining. Results: OCT imaging visualized the microarchitecture of the testis, epididymis, spermatic duct and the ovary, oviduct and uterus. Using the Thorlabs systems a axial resolution of approx. 5μm and lateral resolution of 8- 15μm could be achieved. Different optical tissue volumes could be visualized, which depends on the optical penetration depth of the wavelength of the system used. While the tissue volume observed by probe based Imalux-OCT is similar to the used Thorlabs systems, the optical resolution is

  9. Latency of multifocal visual evoked potentials in nonoptic neuritis eyes of multiple sclerosis patients associated with optic radiation lesions.

    PubMed

    Alshowaeir, Daniah; Yiannikas, Con; Garrick, Raymond; Parratt, John; Barnett, Michael H; Graham, Stuart L; Klistorner, Alexander

    2014-05-15

    The aim of the study was to test the hypothesis that latency delay of multifocal visual evoked potentials (mfVEP) in nonoptic neuritis (NON) eyes of multiple sclerosis (MS) patients is related to retrochiasmal demyelinating lesions. A total of 57 MS patients with no history of optic neuritis at least in one eye, and 25 age- and sex-matched healthy controls was enrolled. Probabilistic tractography was used to reconstruct optic radiation (OR) fibers. The MS lesion volume within and outside of OR was calculated. Diffusion tensor imaging (DTI) indices were measured along OR fibers. The relationship of the mfVEP latency with OR lesions and DTI indices was examined. Average mfVEP latency in the MS cohort was significantly delayed compared to controls (P < 0.0001). Of the patients, 77% demonstrated OR lesions. Axial, radial, and mean diffusivity were significantly abnormal in MS patients (P < 0.001). Partial correlation demonstrated significant association between mfVEP latency delay and OR lesion load. There was also significant correlation between MfVEP latency and OR DTI. Subgroup analysis revealed significantly higher correlations in patients without a history of ON in either eye compared to the fellow eye of patients with previous ON. The findings of this study support our hypothesis that latency delay of the mfVEP in eyes of MS patients without previous ON is related to retrogenicular demyelinating lesions. Additionally, this study demonstrated that a previous episode of ON in the fellow eye may be a significant confounding factor, masking the relationship between the latency and OR lesions. Copyright 2014 The Association for Research in Vision and Ophthalmology, Inc.

  10. Axonal loss in non-optic neuritis eyes of patients with multiple sclerosis linked to delayed visual evoked potential.

    PubMed

    Klistorner, Alexandr; Garrick, Raymond; Barnett, Michael H; Graham, Stuart L; Arvind, Hemamalini; Sriram, Prema; Yiannikas, Con

    2013-01-15

    Recent studies demonstrate significant thinning of the retinal nerve fiber layer (RNFL) in multiple sclerosis (MS) non-optic neuritis (MS-NON) eyes. However, the pathologic basis of this reduction is not clear. The aim of the current study was to investigate the relationship of the RNFL thickness in MS-NON eyes with latency delay of the multifocal visual evoked potential (mfVEP), a surrogate marker of the visual pathway demyelination. Total and temporal RNFL thickness and latency of the mfVEP in 45 MS-NON eyes of 45 patients with relapsing-remitting MS and 25 eyes of age- and gender-matched controls were measured and analyzed. There was significant reduction of total and temporal RNFL thickness (p = 0.015 and p = 0.006, respectively) and significant latency delay (p < 0.0001) in MS-NON eyes. Both total and temporal RNFL thickness were associated with latency of the mfVEP (r2 = 0.43, p < 0.0001 and r2 = 0.36, p = 0.001, respectively). MS-NON eyes with normal latency (n = 26) showed no significant reduction of RNFL thickness compared with controls (p = 0.44 and p = 0.1 for total and temporal RNFL, respectively), whereas eyes with delayed latency (n = 19) demonstrated significantly thinner RNFL (p = 0.001 and p = 0.0005). MS-NON eyes with delayed latency also had significantly thinner RNFL compared with those with normal latencies (p = 0.013 and p = 0.02). In patients with no previous optic neuritis in either eye, delayed latency and reduced RNFL were bilateral whenever present. The study demonstrated significant association between RNFL loss and a latency delay of the mfVEP in MS-NON eyes.

  11. THE POTENTIAL IMPORTANCE OF BINARY EVOLUTION IN ULTRAVIOLET-OPTICAL SPECTRAL FITTING OF EARLY-TYPE GALAXIES

    SciTech Connect

    Li, Zhongmu; Mao, Caiyan; Chen, Li; Zhang, Qian; Li, Maocai

    2013-10-10

    Most galaxies possibly contain some binaries, and more than half of Galactic hot subdwarf stars, which are thought to be a possible origin of the UV-upturn of old stellar populations, are found in binaries. However, the effect of binary evolution has not been taken into account in most works on the spectral fitting of galaxies. This paper studies the role of binary evolution in the spectral fitting of early-type galaxies, via a stellar population synthesis model including both single and binary star populations. Spectra from ultraviolet to optical bands are fitted to determine a few galaxy parameters. The results show that the inclusion of binaries in stellar population models may lead to obvious change in the determination of some parameters of early-type galaxies and therefore it is potentially important for spectral studies. In particular, the ages of young components of composite stellar populations become much older when using binary star population models instead of single star population models. This implies that binary star population models will measure significantly different star formation histories for early-type galaxies compared to single star population models. In addition, stellar population models with binary interactions on average measure larger dust extinctions than single star population models. This suggests that when binary star population models are used, negative extinctions are possibly no longer necessary in the spectral fitting of galaxies (see previous works, e.g., Cid Fernandes et al. for comparison). Furthermore, it is shown that optical spectra have strong constraints on stellar age while UV spectra have strong constraints on binary fraction. Finally, our results suggest that binary star population models can provide new insight into the stellar properties of globular clusters.

  12. Optics and remote sensing of Bahamian carbonate sediment whitings and potential relationship to wind-driven Langmuir circulation

    NASA Astrophysics Data System (ADS)

    Dierssen, H. M.; Zimmerman, R. C.; Burdige, D. J.

    2009-03-01

    Regions of milky white seas or "whitings" periodically occur to the west of Andros Island along the Great Bahama Bank where the bottom sediment consists of fine-grained aragonite mud. We present measurements of inherent optical properties within a sediment whiting patch and discuss the potential for monitoring the frequency, extent, and quantity of suspended matter from ocean colour satellite imagery. Sea spectral reflectance measured in situ and remotely from space revealed highly reflective waters elevated across the visible spectrum (i.e., "whitened") with a peak at 490 nm. Particulate backscattering was an order of magnitude higher than that measured at other stations throughout the region. The whiting also had one of the highest backscattering ratios measured in natural waters (0.05-0.06) consistent with water dominated by aragonite particles with a high index of refraction. Regular periodicity of 40 and 212 s evident in the light attenuation coefficient over the sampling period indicated patches of fluctuating turbidity on spatial scales that could be produced from regular rows of Langmuir cells penetrating the 5-m water column. We suggest that previously described mechanisms for sediment resuspension in whitings, such as tidal bursting and fish activity, are not fully consistent with these data and propose that wind-driven Langmuir cells reaching the full-depth of the water column may represent a plausible mechanism for sediment resuspension and subsequent whiting formation. Optics and remote sensing provide important tools for quantifying the linkages between physical and biogeochemical processes in these dynamic shallow water ecosystems.

  13. Optics and remote sensing of Bahamian carbonate sediment whitings and potential relationship to wind-driven Langmuir circulation

    NASA Astrophysics Data System (ADS)

    Dierssen, H. M.; Zimmerman, R. C.; Burdige, D. J.

    2008-12-01

    Regions of milky white seas or "whitings" periodically occur to the west of Andros Island along the Great Bahama Bank where the bottom sediment consists of fine-grained aragonite mud. We present comprehensive measurements of inherent optical properties within a whiting patch and discuss the potential for monitoring the frequency, extent, and quantity of suspended matter from ocean colour satellite imagery. Sea spectral reflectance measured in situ and remotely from space revealed highly reflective waters elevated across the visible spectrum (i.e., "whitened") with a peak at 490 nm. Particulate backscattering was an order of magnitude higher than that measured at other stations throughout the region. The whiting also had one of the highest backscattering ratios measured in natural waters (0.05-0.06) consistent with water dominated by aragonite particles with a high index of refraction. Regular periodicity of 40 and 212 s evident in the light attenuation coefficient over the sampling period indicated patches of fluctuating turbidity on spatial scales that could be produced from regular rows of Langmuir cells penetrating the 5-m water column. We suggest that previously described mechanisms for sediment resuspension in whitings, such as tidal bursting and fish activity, are not fully consistent with these data and propose that wind-driven Langmuir cells reaching the full-depth of the water column may represent a plausible mechanism for sediment resuspension and subsequent whiting formation. Optics and remote sensing provide important tools for quantifying the linkages between physical and biogeochemical processes in these dynamic shallow water ecosystems.

  14. Structural, thermal, optical properties and cytotoxicity of PMMA/ZnO fibers and films: Potential application in tissue engineering

    NASA Astrophysics Data System (ADS)

    Balen, Rodrigo; da Costa, Wilian Vidotto; de Lara Andrade, Jéssica; Piai, Juliana Francis; Muniz, Edvani Curti; Companhoni, Mychelle Vianna; Nakamura, Tânia Ueda; Lima, Sandro Marcio; da Cunha Andrade, Luis Humberto; Bittencourt, Paulo Rodrigo Stival; Hechenleitner, Ana Adelina Winkler; Pineda, Edgardo Alfonso Gómez; Fernandes, Daniela Martins

    2016-11-01

    Films and fibers of PMMA/ZnO nanocomposites (100/0, 99/01, 97/03, 95/05, 90/10, and 85/15 wt.%) were produced by casting and electrospinning, respectively. Their structural, thermal, and optical properties were investigated by XRD, SEM, TGA, PAS, and PL. The incorporation of ZnO NPs reduced the diameter of PMMA fibers and the presence of beads. The surfaces of the fibers exhibited greater hydrophobicity, compared to the films, with contact angles of around 120° and 94°, respectively. PMMA films containing ZnO exhibited higher thermal stability than the pure polymer, while the corresponding fibers did not show any changes in thermal stability. The dispersion of the ZnO NPs at the surface and in the bulk of the nanocomposites appeared to be relatively homogeneous. ZnO improved the optical properties of the PMMA, with an intense absorption band near 370 nm observed for all the nanocomposites, which also exhibited luminescence with emission in the near-UV region, both attributed to ZnO. Biological tests demonstrated that fibers and films with up to 1% of ZnO exhibited good performance in the proliferation of fibroblast cells, indicating their potential for applications in tissue engineering. The fibers provided higher cell viability than the films, presumably due to their greater surface area and/or more suitable surface morphology. Nanocomposites with 15% ZnO inhibited cell proliferation, due to the cytotoxicity of the ZnO NPs. Although several applications of PMMA have been suggested by biomedical researchers, until now there have been no reports on the specific uses of fibers and films of PMMA/ZnO nanocomposites as scaffolds for fibroblast cell proliferation.

  15. Unravelling the correlated electronic and optical properties of BaTaO2N with perovskite-type structure as a potential candidate for solar energy conversion.

    PubMed

    Hafez, Ahmed M; Salem, Noha M; Allam, Nageh K

    2014-09-14

    We report on the first principles calculation of the electronic, structural and optical properties of BaTaO2N, using density functional theory (DFT) and finite difference time domain (FDTD) methods. Band structure calculations were performed to calculate the direct and indirect bandgaps of the material. Density of states and Mulliken charge analysis as well as the electronic contour maps were established to determine the type of bonding and hybridization between the various electronic states. The dielectric constant, reflectivity, absorption, optical conductivity and energy-loss function were also calculated. Moreover, FDTD was used to investigate the optical properties of a larger and more reliable structure of BaTaO2N powder in good agreement with the reported experimental parameters. The calculated electronic, structural and optical properties showed the potential of BaTaO2N for solar energy conversion and optoelectronic applications.

  16. Highly nonlinear chalcogenide hybrid microstructured optical fibers with buffer layer and their potential performance of supercontinuum generation

    NASA Astrophysics Data System (ADS)

    Tong, Hoang Tuan; Nagasaka, Kenshiro; Nguyen Phuoc, Trung Hoa; Suzuki, Takenobu; Ohishi, Yasutake

    2017-02-01

    We report here the design of a new chalcogenide hybrid microstructured optical fiber (HMOF) with a buffer layer around the core and its potential performance of tailoring chromatic dispersion and supercontinuum (SC) generation. The new chalcogenide HMOF has an AsSe2 core. The refractive index difference Δn between the AsSe2 core and cladding material is supposed to be 0.3. The fiber microstructure and the Δn between the core and buffer materials are designed in order to obtain broad anomalous dispersion regimes with near-zero and flattened chromatic dispersion profiles for broadband SC generation. Moreover, the suppression of chromatic dispersion fluctuation caused by fiber transverse geometry variation is investigated. By using the proposed chalcogenide buffer-embed HMOFs, the calculation shows that near-zero and flattened anomalous chromatic dispersion regimes from 4.5 μm can be obtained. When the variation of fiber structure occurs for +/-1, +/-5 and +/-10 %, the chromatic dispersion fluctuation can be greatly suppressed. In addition, the calculation shows that a broad SC spectrum from 2.5 to more than 16.0 μm can be obtained when a 0.9-cmlong section of the new chalcogenide buffer-embed HMOF is pumped at 5.0 μm by a femtosecond laser with 1-kW peak power.

  17. Optical coherence tomography: a potential tool for prediction of treatment response for port wine stain after photodynamic therapy

    NASA Astrophysics Data System (ADS)

    Zhen, Jie; Wang, Chengming; Wang, Ying; Chen, Defu; Gu, Ying

    2014-11-01

    Response of port wine stain (PWS) to photodynamic therapy treatment (PDT) is variable and depends on treatment setting used and anatomic sites as well as on size and depth of ectatic vessels. Optical coherence tomography (OCT) is a non-destructive imaging modality which can reveal the layered structure of the upper part of the skin. The structural features of the PWS skin such as the diameter and depth of the blood vessels in different anatomic sites can be showed in the OCT images. In this study, the possible role of PWS skin structure in the response to PDT is assessed. 82 positions from 43 patients with PWS underwent OCT evaluation in cheek, zygomatic aera, preauricular and temporal region before and 3~4 months after the first PDT when treatment outcomes were also evaluated. After analyzing the structural features in different anatomic sites and the therapeutic effect of them, we found that the ectatic vessels diameter was obvious bigger in the cheek which had slightly poorer outcomes than other areas. Some typical structures had poor or good outcomes after first PDT. These can help the clinic doctors predict the response of some patients which have typical structures after PDT treatment. The OCT will be a potential tool for prediction of treatment response for port wine stain after photodynamic therapy.

  18. Temperature-dependent evaluation of Nd:LiCAF optical properties as potential vacuum ultraviolet laser material

    NASA Astrophysics Data System (ADS)

    Minami, Yuki; Arita, Ren; Cadatal-Raduban, Marilou; Pham, Minh Hong; Empizo, Melvin John Fernandez; Luong, Mui Viet; Hori, Tatsuhiro; Takabatake, Masahiro; Fukuda, Kazuhito; Mori, Kazuyuki; Yamanoi, Kohei; Shimizu, Toshihiko; Sarukura, Nobuhiko; Fukuda, Kentaro; Kawaguchi, Noriaki; Yokota, Yuui; Yoshikawa, Akira

    2016-08-01

    We investigate the temperature-dependent optical properties of Nd3+-doped LiCaAlF6 (Nd:LiCAF) in the vacuum ultraviolet (VUV) region. The 172-nm absorption edge does not seem to experience any significant blue shift as temperature is decreased from room temperature down to 30 K. This is confirmed by excitation spectra for the same temperature range. Several energy levels in the excited state configuration are observed. Based on these energy levels, the dominant emission peak at 177 nm is assigned to the allowed dipole transition from the 4f25d configuration of Nd3+ and the 4I11/2 level of the 4f3 ground state configuration. The position of the dominant 177-nm emission peak appears to be fixed across the temperature range considered. Our results suggest that the spectral overlap between the excitation and emission spectra should not increase as temperature is raised, possibly making Nd:LiCAF a potential VUV laser gain medium operating at room temperature.

  19. Neuronal excitation and permeabilization by 200-ns pulsed electric field: An optical membrane potential study with FluoVolt dye.

    PubMed

    Pakhomov, Andrei G; Semenov, Iurii; Casciola, Maura; Xiao, Shu

    2017-07-01

    Electric field pulses of nano- and picosecond duration are a novel modality for neurostimulation, activation of Ca(2+) signaling, and tissue ablation. However it is not known how such brief pulses activate voltage-gated ion channels. We studied excitation and electroporation of hippocampal neurons by 200-ns pulsed electric field (nsPEF), by means of time-lapse imaging of the optical membrane potential (OMP) with FluoVolt dye. Electroporation abruptly shifted OMP to a more depolarized level, which was reached within <1ms. The OMP recovery started rapidly (τ=8-12ms) but gradually slowed down (to τ>10s), so cells remained above the resting OMP level for at least 20-30s. Activation of voltage-gated sodium channels (VGSC) enhanced the depolarizing effect of electroporation, resulting in an additional tetrodotoxin-sensitive OMP peak in 4-5ms after nsPEF. Omitting Ca(2+) in the extracellular solution did not reduce the depolarization, suggesting no contribution of voltage-gated calcium channels (VGCC). In 40% of neurons, nsPEF triggered a single action potential (AP), with the median threshold of 3kV/cm (range: 1.9-4kV/cm); no APs could be evoked by stimuli below the electroporation threshold (1.5-1.9kV/cm). VGSC opening could already be detected in 0.5ms after nsPEF, which is too fast to be mediated by the depolarizing effect of electroporation. The overlap of electroporation and AP thresholds does not necessarily reflect the causal relation, but suggests a low potency of nsPEF, as compared to conventional electrostimulation, for VGSC activation and AP induction. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. Theoretical Investigation Optical Properties of Si12C12 Clusters and Oligomers having Potential as Excitonic Materials

    NASA Astrophysics Data System (ADS)

    Duan, Xiaofeng; Burggraf, Larry

    2015-03-01

    SiC clusters may have potential in 2-D exciton circuits. We determined the most stable SinCn isomer structures (n <=12) out of hundreds to thousands isomers using a method combining Stochastic Potential Surface Search and Pseududopotential Plane-Wave Density Functional Theory Car-Parinello Molecular Dynamics simulated annealing (PSPW-CPMD-SA). Four low-energy Si12C12 isomer structures are discussed to illustrate the varying optical properties of clusters with structures: i) cage type with C- and Si- segregations, ii) symmetric type formed having π-stacked C aromatic rings and exterior Si regions, iii) nearly planar bowl with C fullerene fragment surrounded by Si atoms, and iv) symmetrical SiC cluster having alternate SiC bonding in the structure. We employed B3LYP and PBE0 functionals and both cc-pVTZ and aug-cc-pVTZ basis sets to perform TDDFT calculations of excitation energies and photo-absorption spectra to show how structure and bonding patterns affect photo excitations in different types of SiC clusters. The electron and the hole charge distribution patterns in excitation were calculated for major photoabsorption transitions, reported for the most stable isomer, closo Si12C12. To understand electric field effects we also calculated dynamical polarizabilities for all the four structures using Coupled Perturbed Hartree-Fock (CPHF) at B3LYP/aug-cc-pVTZ and PBE0/aug-cc-pVTZ level of theory. We gratefully acknowledge support from the Air Force Office of Scientific Research in a program managed by Dr Michael Berman.

  1. Potential of Solid Sampling Electrothermal Vaporization for solving spectral interference in Inductively Coupled Plasma Optical Emission Spectrometry

    NASA Astrophysics Data System (ADS)

    Asfaw, Alemayehu; Wibetoe, Grethe

    2009-05-01

    Spectral interference is one of the main causes of erroneous results in Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES). This paper describes some cases of spectral interferences with conventional nebulization ICP-OES and the potential of solving them utilizing electrothermal vaporization for volatility-based separation. The cases studied were, the well-known spectral overlap between the As and Cd lines at 228.8 nm that are only 10 pm apart, and the interference of Fe on the main emission lines of As, Cd and Pb. The spectral interferences were studied by monitoring the typical signals of solutions that contain the analytes and the potential interferent, by studying the spectra and calculating Background Equivalent Concentration (BEC)-values. A three step temperature program was developed to be used for direct analysis of solid soil samples by Electrothermal Vaporization (ETV)-ICP-OES: step 1 (760 °C, 40 s), step 2 (1620 °C, 20 s) and a cleaning step (2250 °C, 10 s) where Cd vaporizes in step 1, As, Pb and part of Fe in step 2 and the major part of Fe in the cleaning step. Because As and Cd were time-separated using this program, their prominent lines at 228.8 nm, could be used for determination of each element by ETV-ICP-OES, in spite of the serious wavelength overlap. Selective vaporization was also shown to reduce or eliminate the Fe background emission on As, Cd and Pb lines. To confirm the applicability of the method, a solid soil certified reference materials was analyzed directly without any sample treatment. Good or reasonable accuracy was obtained for the three elements.

  2. A long-time, high spatiotemporal resolution optical recording system for membrane potential activity via real-time writing to the hard disk.

    PubMed

    Hirota, Akihiko; Ito, Shin-ichi

    2006-06-01

    Using real-time hard disk recording, we have developed an optical system for the long-duration detection of changes in membrane potential from 1,020 sites with a high temporal resolution. The signal-to-noise ratio was sufficient for analyzing the spreading pattern of excitatory waves in frog atria in a single sweep.

  3. Potential for Optical Sensor-Based Nitrogen Fertilization in Grain Sorghum (Sorghum bicolor L. Moench) in Arkansas

    NASA Astrophysics Data System (ADS)

    Rosales Rodriguez, Kamil

    Ground-based active-optical (GBAO) crop sensors have become an effective tool to improve nitrogen (N) use efficiency and to predict yield early in the growing season, particularly for grass crops. Commercially available canopy sensors calculate the normalized difference vegetative index (NDVI) by emitting light in the red and near infrared range of the electromagnetic spectrum. The NDVI is used to evaluate vigor status and to estimate yield potential. However, few studies have been conducted to compare the performance of commercially available sensors. Therefore, a study was conducted using the most common crop canopy sensors: i) N-Tech's GreenSeeker(TM) (GS), ii) Holland Scientific's Crop Circle(TM) (CC), and iii) Minolta's SPAD-502 chlorophyll content meter (CCM). The objective of this study was to find the optimum time for sensing and compare the relative performance of the sensors in estimating the yield potential of grain sorghum (Sorghum bicolor L. Moench). Treatments included six levels of N fertilization (0, 37, 74, 111, 148, and 185 kg N/ ha), applied in a single split 20 days after planting (DAP). Treatments were arranged in a randomized complete block design with five replications, in four locations in Arkansas, during 2012 and 2013. Sensors readings at vegetative growth stages V3, 4, 5 and 6. Results from simple regression analysis showed that the V3-V4 growth stage correlated better with grain yield than readings collected and any other time. In season estimated yield (INSEY) obtained at V3 captured 41, 57, 78, and 61% of the variation in grain sorghum yield when red NDVI of GS, red NDVI of CC, red edge for CC and CCM, respectively, were used. Results from these studies suggest that the CC sensor has a better potential for in-season site-specific N application in Arkansas than the GS sensor. The GS reflectance values appear to saturate after the V3 stage, in contrast with CC values that allow for discrimination past the V3 Stage. Therefore, the red

  4. Carbon/Ternary Alloy/Carbon Optical Stack on Mylar as an Optical Data Storage Medium to Potentially Replace Magnetic Tape

    SciTech Connect

    Wang, Hao; Lunt, Barry M.; Gates, Richard J.; Asplund, Matthew C.; Shutthanandan, V.; Davis, Robert C.; Linford, Matthew R.

    2013-09-11

    A novel write-once-read-many (WORM) optical stack on Mylar tape is proposed as a replacement for magnetic tape for archival data storage. This optical tape contains a cosputtered bismuth–tellurium–selenium (BTS) alloy as the write layer sandwiched between thin, protective films of reactively sputtered carbon. The composition and thickness of the BTS layer were confirmed by Rutherford Backscattering (RBS) and atomic force microscopy (AFM), respectively. The C/BTS/C stack on Mylar was written to/marked by 532 nm laser pulses. Under the same conditions, control Mylar films without the optical stack were unaffected. Marks, which showed craters/movement of the write material, were characterized by optical microscopy and AFM. The threshold laser powers for making marks on C/BTS/C stacks with different thicknesses were explored. Higher quality marks were made with a 60× objective compared to a 40× objective in our marking apparatus. Finally, the laser writing process was simulated with COMSOL.

  5. An Exploration of Professional Culture Differentials and Their Potential Impact on the Information Assurance Component of Optical Transmission Networks Design

    ERIC Educational Resources Information Center

    Cuthrell, Michael Gerard

    2011-01-01

    Optical transmission networks are an integral component of the critical infrastructures for many nations. Many people believe that optical transmission networks are impenetrable. In actuality, these networks possess weaknesses that can be exploited to bring about harm. An emerging Information Assurance (IA) industry has as its goals: to…

  6. An Exploration of Professional Culture Differentials and Their Potential Impact on the Information Assurance Component of Optical Transmission Networks Design

    ERIC Educational Resources Information Center

    Cuthrell, Michael Gerard

    2011-01-01

    Optical transmission networks are an integral component of the critical infrastructures for many nations. Many people believe that optical transmission networks are impenetrable. In actuality, these networks possess weaknesses that can be exploited to bring about harm. An emerging Information Assurance (IA) industry has as its goals: to…

  7. An investigation of the potential of optical computed tomography for imaging of synchrotron-generated x-rays at high spatial resolution

    NASA Astrophysics Data System (ADS)

    Doran, Simon J.; Brochard, Thierry; Adamovics, John; Krstajic, Nikola; Bräuer-Krisch, Elke

    2010-03-01

    X-ray microbeam radiation therapy (MRT) is a novel form of treatment, currently in its preclinical stage, which uses microplanar x-ray beams from a synchrotron radiation source. It is important to perform accurate dosimetry on these microbeams, but, to date, there has been no accurate enough method available for making 3D dose measurements with isotropic, high spatial resolution to verify the results of Monte Carlo dose simulations. Here, we investigate the potential of optical computed tomography for satisfying these requirements. The construction of a simple optical CT microscopy (optical projection tomography) system from standard commercially available hardware is described. The measurement of optical densities in projection data is shown to be highly linear (r2 = 0.999). The depth-of-field (DOF) of the imaging system is calculated based on the previous literature and measured experimentally using a commercial DOF target. It is shown that high quality images can be acquired despite the evident lack of telecentricity and despite DOF of the system being much lower than the sample diameter. Possible reasons for this are discussed. Results are presented for a complex irradiation of a 22 mm diameter cylinder of the radiochromic polymer PRESAGE™, demonstrating the exquisite 'dose-painting' abilities available in the MRT hutch of beamline ID-17 at the European Synchrotron Radiation Facility. Dose distributions in this initial experiment are equally well resolved on both an optical CT scan and a corresponding transmission image of radiochromic film, down to a line width of 83 µm (6 lp mm-1) with an MTF value of 0.40. A group of 33 µm wide lines was poorly resolved on both the optical CT and film images, and this is attributed to an incorrect exposure time calculation, leading to under-delivery of dose. Image artefacts in the optical CT scan are discussed. PRESAGE™ irradiated using the microbeam facility is proposed as a suitable material for producing phantom

  8. Exciton-related nonlinear optical properties in cylindrical quantum dots with asymmetric axial potential: combined effects of hydrostatic pressure, intense laser field, and applied electric field

    PubMed Central

    2012-01-01

    The exciton binding energy of an asymmetrical GaAs-Ga1−xAlxAs cylindrical quantum dot is studied with the use of the effective mass approximation and a variational calculation procedure. The influence on this quantity of the application of a direct-current electric field along the growth direction of the cylinder, together with that of an intense laser field, is particularly considered. The resulting states are used to calculate the exciton-related nonlinear optical absorption and optical rectification, whose corresponding resonant peaks are reported as functions of the external probes, the quantum dot dimensions, and the aluminum molar fraction in the potential barrier regions. PMID:22971418

  9. The Potential Role of Optical Coherence Tomography in the Evaluation of Vulnerable Carotid Atheromatous Plaques: A Pilot Study

    SciTech Connect

    Prabhudesai, Vikramaditya; Phelan, Cordelia; Yang, Ying Wang, Ruikang K.; Cowling, Mark G.

    2006-12-15

    Purpose. The decision to intervene surgically in patients with carotid artery disease is based on the presence of symptoms, along with the severity of carotid artery stenosis as assessed by ultrasound or X-ray computed tomography (CT). Optical coherence tomography (OCT) is a relatively new imaging technique that offers potential in the identification of, as well as the distinction between, stable and unstable atherosclerotic plaques. The purpose of our study was to evaluate whether OCT can be used as a noninvasive diagnostic tool to reveal the morphology of carotid stenosis from the adventitial surface of the carotid artery. To achieve this aim, excised atheromatous plaques were scanned by OCT from the external surface. Methods. Plaques removed at carotid endarterectomy were scanned by OCT from the external surface within 72 hr of surgery and then examined histologically. The images of the histologic slides and the scans were then compared. Results. We examined 10 carotid endarterectomy specimens and were able to identify calcification, cholesterol crystal clefts, and lipid deposits in the OCT images with histologic correlation. The strong light scattering from the calcified tissue and cholesterol crystal clefts limited the depth of light penetration, making observation of the intimal surface and the detail of the fibrous cap difficult. However, we were able to confidently identify the absence of an atherosclerotic plaque by OCT scans even from the external surface. Conclusion. The results of this pilot study demonstrate that OCT can reveal the main features of carotid stenosis but that plaque vulnerability cannot be reliably and precisely assessed if scanned from the external surface with OCT in its present form.

  10. The nonlinear optical rectification and second harmonic generation in asymmetrical Gaussian potential quantum well: Effects of hydrostatic pressure, temperature and magnetic field

    NASA Astrophysics Data System (ADS)

    Liu, Xin; Zou, LiLi; Liu, Chenglin; Zhang, Zhi-Hai; Yuan, Jian-Hui

    2016-03-01

    In the present work, the effects of hydrostatic pressure, temperature, and magnetic field on the nonlinear optical rectification (OR) and second-harmonic generation (SHG) in asymmetrical Gaussian potential quantum well (QW) have been investigated theoretically. Here, the expressions for the optical properties are calculated by the compact-density-matrix approach and iterative method. Simultaneously, the energy eigenvalues and their corresponding eigenfunctions have been obtained by using the finite difference method. The energy eigenvalues and the shape of the confined potential are modulated by the hydrostatic pressure, temperature, and magnetic field. So the results of a number of numerical experiments indicate that the nonlinear OR and SHG strongly depends on the hydrostatic pressure, temperature, and magnetic field. This gives a new degree of freedom in various device applications based on the intersubband transitions of electrons.

  11. Tuning FlaSh: redesign of the dynamics, voltage range, and color of the genetically encoded optical sensor of membrane potential.

    PubMed

    Guerrero, Giovanna; Siegel, Micah S; Roska, Botond; Loots, Eli; Isacoff, Ehud Y

    2002-12-01

    The optical voltage sensor FlaSh, made from a fusion of a GFP "reporter domain" and a voltage-gated Shaker K(+) channel "detector domain," has been mutagenically tuned in both the GFP reporter and channel detector domains. This has produced sensors with improved folding at 37 degrees C, enabling use in mammalian preparations, and yielded variants with distinct spectra, kinetics, and voltage dependence, thus expanding the types of electrical signals that can be detected. The optical readout of FlaSh has also been expanded from single wavelength fluorescence intensity changes to dual wavelength measurements based on both voltage-dependent spectral shifts and changes in FRET. Different versions of FlaSh can now be chosen to optimize the detection of either action potentials or synaptic potentials, to follow high versus low rates of activity, and to best reflect electrical activity in cell types with distinct voltages of operation.

  12. First application of the n - 9Be optical potential to the study of the 10Be continuum via the (18O,17O ) neutron-transfer reaction

    NASA Astrophysics Data System (ADS)

    Carbone, D.; Bondı, M.; Bonaccorso, A.; Agodi, C.; Cappuzzello, F.; Cavallaro, M.; Charity, R. J.; Cunsolo, A.; De Napoli, M.; Foti, A.

    2014-12-01

    The 9Be(18O,17O ) 10Be reaction has been studied at an incident energy of 84 MeV, and the ejectiles have been detected at forward angles. The 10Be excitation energy spectrum has been obtained up to about 18 MeV, and several known bound and resonant states of 10Be have been identified. Calculations that describe the interaction of the neutron removed from the 18O projectile with the 9Be target by means of an optical potential with a semiclassical approximation for the relative motion account for a significant part of the 10Be continuum. Two parametrizations of the optical-model potential for the system n - 9Be have been used and compared.

  13. An automated system using spatial oversampling for optical mapping in murine atria. Development and validation with monophasic and transmembrane action potentials

    PubMed Central

    Yu, Ting Yue; Syeda, Fahima; Holmes, Andrew P.; Osborne, Benjamin; Dehghani, Hamid; Brain, Keith L.; Kirchhof, Paulus; Fabritz, Larissa

    2014-01-01

    We developed and validated a new optical mapping system for quantification of electrical activation and repolarisation in murine atria. The system makes use of a novel 2nd generation complementary metal-oxide-semiconductor (CMOS) camera with deliberate oversampling to allow both assessment of electrical activation with high spatial and temporal resolution (128 × 2048 pixels) and reliable assessment of atrial murine repolarisation using post-processing of signals. Optical recordings were taken from isolated, superfused and electrically stimulated murine left atria. The system reliably describes activation sequences, identifies areas of functional block, and allows quantification of conduction velocities and vectors. Furthermore, the system records murine atrial action potentials with comparable duration to both monophasic and transmembrane action potentials in murine atria. PMID:25130572

  14. Potential of bismuth nanoparticles embedded in a glass matrix for spectral-selective thermo-optical devices

    NASA Astrophysics Data System (ADS)

    Jiménez de Castro, M.; Cabello, F.; Toudert, J.; Serna, R.; Haro-Poniatowski, E.

    2014-09-01

    The optical transmission at a fixed visible wavelength of Bi nanoparticles embedded in a dielectric is known to show a sharp hysteretic evolution as a function of the temperature due to the reversible melting-solidification of the nanoparticles. In this work, we explore the temperature-dependent optical response of Bi nanoparticles embedded in a doped germanate glass (GeO2-Al2O3-Na2O) in a broad range from the visible to the near infrared. The transmission contrast induced by melting of the nanoparticles is shown to be strongly wavelength-dependent and evolves from positive to negative as the wavelength increases. This behaviour is well modelled using effective medium calculations, assuming that the nanoparticles size, shape, and distribution are unmodified upon melting, while their dielectric function turns from that of solid Bi to that of liquid Bi thus modifying markedly their optical response. These results open a route to the spectral tailoring of the thermo-optical response of Bi nanoparticles-based materials, which can be profitable for the engineering of wavelength-selective thermo-optical modulators and filters with optimized amplitude of modulation and wavelength dependence.

  15. Light radioactive nuclei capture reactions with phenomenological potential models

    SciTech Connect

    Guimaraes, V.; Bertulani, C. A.

    2010-05-21

    Light radioactive nuclei play an important role in many astrophysical environments. Due to very low cross sections of some neutron and proton capture reactions by these radioactive nuclei at energies of astrophysical interest, direct laboratory measurements are very difficult. For radioactive nuclei such as {sup 8}Li and {sup 8}B, the direct measurement of neutron capture reactions is impossible. Indirect methods have been applied to overcome these difficulties. In this work we will report on the results and discussion of phenomenological potential models used to determine some proton and neutron capture reactions. As a test we show the results for the {sup 16}O(p,gamma){sup 17}F{sub gs}(5/2{sup +}) and {sup 16}O(p,gamma){sup 17}F{sub ex}(1/2{sup +}) capture reactions. We also computed the nucleosynthesis cross sections for the {sup 7}Li(n,gamma){sup 8}Li{sub gs}, {sup 8}Li(n,gamma){sup 9}Li{sub gs} and {sup 8}B(p,gamma){sup 9}C{sub gs} capture reactions.

  16. Optic Nerve.

    PubMed

    Gordon, Lynn K

    2016-10-28

    Optic nerve diseases arise from many different etiologies including inflammatory, neoplastic, genetic, infectious, ischemic, and idiopathic. Understanding some of the characteristics of the most common optic neuropathies along with therapeutic approaches to these diseases is helpful in designing recommendations for individual patients. Although many optic neuropathies have no specific treatment, some do, and it is those potentially treatable or preventable conditions which need to be recognized in order to help patients regain their sight or develop a better understanding of their own prognosis. In this chapter several diseases are discussed including idiopathic intracranial hypertension, optic neuritis, ischemic optic neuropathies, hereditary optic neuropathies, trauma, and primary tumors of the optic nerve. For each condition there is a presentation of the signs and symptoms of the disease, in some conditions the evaluation and diagnostic criteria are highlighted, and where possible, current therapy or past trials are discussed.

  17. Elastic and inelastic scattering of 240-MeV {sup 6}Li ions from {sup 40}Ca and {sup 48}Ca and tests of a systematic optical potential

    SciTech Connect

    Krishichayan,; Chen, X.; Lui, Y.-W.; Button, J.; Youngblood, D. H.

    2010-04-15

    Elastic and inelastic scattering of 240-MeV {sup 6}Li particles from {sup 40}Ca and {sup 48}Ca were measured with the multipole-dipole-multipole spectrometer from 4 deg. <=theta{sub c.m.}<=40 deg. Optical potential parameters were obtained by fitting the elastic-scattering data with the double-folding model using the density-dependent M3Y NN effective interaction and B(E2) and B(E3) values obtained for low-lying 2{sup +} and 3{sup -} states agreed with the adopted values. The results are compared with those obtained using potentials derived from the systematics of potentials previously obtained for {sup 24}Mg, {sup 28}Si, {sup 58}Ni, and {sup 90}Zr. Cross sections for excitation of giant resonances were also calculated with the potentials obtained.

  18. Growth, spectral, anisotropic, second and third order nonlinear optical studies on potential nonlinear optical crystal anilinium perchlorate (AP) for NLO device fabrications.

    PubMed

    Vivek, P; Suvitha, A; Murugakoothan, P

    2015-01-05

    A new semiorganic nonlinear optical material anilinium perchlorate was grown by the slow evaporation technique using water as solvent. The solubility and meta stable zone width were determined. The anilinium perchlorate crystal belongs to orthorhombic system with noncentrosymmetric space group P2₁2₁2₁. The presence of various functional groups was identified by FT-IR FT-Raman spectrum. The morphology of the anilinium perchlorate crystal was studied. From this morphology, anilinium perchlorate crystal plate was cut along three prominent planes, such as (001), (010) and (20-1). The thermal stability of the crystal was determined using TG-DTA studies. The hardness, laser damage threshold, transmittance, reflectance, experimental refractive index of the crystal was found. The particle size dependent second harmonic generation efficiency for anilinium perchlorate was evaluated by Kurtz-Perry powder method using Nd:YAG laser, which established the existence of phase matching. The third order nonlinear refractive index and nonlinear absorption coefficient of the grown crystal were measured by Z-scan studies. Copyright © 2014 Elsevier B.V. All rights reserved.

  19. The effects of Co/N dopants on the electronic, redox potential, optical, and photocatalytic water-splitting properties of TiO2: First principles calculations

    NASA Astrophysics Data System (ADS)

    Zhao, Yafei; Wang, Wei; He, Liang

    2017-10-01

    The crystal structure, formation energy, electronic and optical properties of undoped, Co, N doped and co-doped TiO2 were investigated by first principles calculations. Considering the potential of water redox reaction of these systems indicate that only N-, Co-1N- and Co-2N co-doped TiO2 meet the requirement of the photosplitting water. Moreover, the optical absorption threshold and absorption area of Co-2N co-doped TiO2 are obviously enlarged compared with the undoped TiO2. Co-2N co-doped TiO2 has the highest light absorption efficiency and hydrogen production efficiency, due to the presence of curved and broad impurity levels that greatly improve the carriers' mobility and separation.

  20. 2048 QAM (66 Gbit/s) single-carrier coherent optical transmission over 150 km with a potential SE of 15.3 bit/s/Hz.

    PubMed

    Beppu, Shohei; Kasai, Keisuke; Yoshida, Masato; Nakazawa, Masataka

    2015-02-23

    We describe a 2048 QAM single-carrier coherent optical transmission over 150 km in detail. The OSNR at the transmitter was increased by 5 dB and the phase noise at the receiver was reduced from 0.35 to 0.17 degrees compared with a previous 1024 QAM transmission. Furthermore, we employed an A/D converter with a higher ENOB (7 bit) to guarantee the SNR of the digital QAM data, and introduced a polarization-demultiplexing algorithm to fast track the polarization state transition. As a result, a 66 Gbit/s polarization-multiplexed 2048 QAM signal was successfully transmitted within an optical bandwidth of 3.6 GHz including a pilot tone, and a potential SE of 15.3 bit/s/Hz under a 20% FEC overhead was achieved.

  1. Theoretical description of two ultracold atoms in a single site of a three-dimensional optical lattice using realistic interatomic interaction potentials

    SciTech Connect

    Grishkevich, Sergey; Saenz, Alejandro

    2009-07-15

    A theoretical approach was developed for an exact numerical description of a pair of ultracold atoms interacting via a central potential, which is trapped in a three-dimensional optical lattice. The coupling of center-of-mass and relative-motion coordinates is explicitly considered using a configuration-interaction (exact-diagonalization) technique. Deviations from the harmonic approximation are discussed for several heteronuclear alkali-metal atom pairs trapped in a single site of an optical lattice. The consequences are discussed for the analysis of a recent experiment [C. Ospelkaus et al., Phys. Rev. Lett. 97, 120402 (2006)] in which radio-frequency association was used to create diatomic molecules from a fermionic and a bosonic atom and to measure their binding energies close to a magnetic Feshbach resonance.

  2. Density-functional-theory calculations of the total energies, ionization potentials, and optical response properties with the van Leeuwen-Baerends potential

    NASA Astrophysics Data System (ADS)

    Banerjee, Arup; Harbola, Manoj K.

    1999-11-01

    van Leeuwen and Baerends proposed a Becke-like nonlocal correction to the local-density-approximation (LDA) exchange-correlation potential so that its asymptotic structure becomes exact i.e., -1/r [Phys. Rev. A 49, 2421 (1994)]. They showed that it significantly improves the value of the highest occupied orbital eigenvalue of atoms and molecules. However, the correction is exchangelike in nature. With this in mind, in this paper we investigate how this correction affects the total energies and highest eigenvalues within the exchange-only approximation. We show that the potential also corrects the LDA errors substantially within this approximation, and leads to total energies and high eigenvalues which compare well with their Hartree-Fock counterparts. Improvement in the asymptotic behavior of the potential should also result in better values of the response properties of these systems. We show that with this correction one obtains better estimates, both within the exchange-only approximation and with correlation included, of the linear and nonlinear polarizabilities of inert gas atoms. This is quite significant, since the LDA is known to overestimate the nonlinear polarizabilities of these atoms by roughly 100%. On the other hand, for alkaline-earth atoms the values of polarizabilities obtained with this correction are not satisfactory. Nonetheless, hyperpolarizabilities show a marked improvement over the LDA results.

  3. Analysis of 4He+40Ca and 4He+44Ti scattering using different optical model potentials

    NASA Astrophysics Data System (ADS)

    Ibraheem, Awad A.

    2016-09-01

    Elastic scattering of 4He+40Ca and 4He+44Ti reactions at backward angles has been analyzed using two differentmodels, microscopic and semimicroscopic folding potentials. The derived real potentials supplemented with phenomenological Woods-Saxon imaginary potentials, provide good agreement with the experimental data at energy E c.m. = 21.8 MeV without need to renormalize the potentials. Coupledchannels calculations are used to extract the inelastic scattering cross section to the low-lying state 2+ (1.083 MeV) of 44Ti. The deformation length is obtained and compared with the electromagnetic measurement values as well as those obtained from previous studies.

  4. Optical nonlinearity of D-A-π-D and D-A-π-A type of new chalcones for potential applications in optical limiting and density functional theory studies

    NASA Astrophysics Data System (ADS)

    Chandra Shekhara Shetty, T.; Chidan Kumar, C. S.; Gagan Patel, K. N.; Chia, Tze Shyang; Dharmaprakash, S. M.; Ramasami, Ponnadurai; Umar, Yunusa; Chandraju, Siddegowda; Quah, Ching Kheng

    2017-09-01

    Two new chalcones namely, (2E)-1-(3-fluoro-4-methoxyphenyl)-3-(4-methoxyphenyl) prop-2-en-1-one and (2E)-3-(4-chlorophenyl)-1-(3-fluoro-4-methoxyphenyl)prop-2-en-1-one were synthesized and grown as single crystals by slow evaporation technique in methanol. The FTIR spectrum recorded confirms the presence of functional groups in these materials. The molecular conformation of the compounds was achieved by single crystal X-ray diffraction studies. The thermal stability of the crystals was determined from TGA/DSC curve. The third order optical nonlinearity of the chalcone compounds in DMF solution has been carried out using an Nd:YAG laser at 532 nm as the source of excitation. The nonlinear optical response was characterized by measuring the intensity dependent refractive index n2 of the medium using Z-scan technique. It is seen that the molecules exhibit a negative (defocusing) nonlinearity and large nonlinear refractive index of the order of -1.8 × 10-11 esu. The third-order nonlinearity of the studied chalcones is dominated by nonlinear refraction, which leads to strong optical limiting of laser. The result reveals that these two new chalcone molecules would be a promising material for optical limiting applications. In addition, the optimized molecular geometry, vibrational frequencies in gas, and the Molecular Electrostatic Potential (MEP) surface parameters of the two molecules were calculated using DFT/B3LYP method with 6-311++G(d,p) basis set in ground state. All the theoretical calculations were found in good agreement with experimental data.

  5. Potentialities of laser systems for remote sensing of the atmosphere at a wide variability of optical and physical characteristics: dimensionless-parametric modelling

    NASA Astrophysics Data System (ADS)

    Agishev, R. R.

    2017-02-01

    Within the framework of generalisation of different approaches to the modelling of atmospheric lidars, the methodology capabilities for dimensionless-parametric analysis are expanded. The developed approach simplifies the analysis of the signal-to-noise ratio and potential capabilities of existing and newly developed monitoring systems with a wide variability of atmospheric and optical conditions and a great variety of modern lidars. Its applicability to the problems of remote atmospheric sensing, environmental monitoring and lidar navigation in providing the eye safety, noise immunity and reliability is discussed.

  6. Broadly tunable, beta-barium-borate-based, pulsed optical parametric oscillators and their potential applications in medicine

    NASA Astrophysics Data System (ADS)

    Sobey, Mark S.; Clark, Jim; Johnson, Bertram C.

    1995-05-01

    With the recent availability of Beta Barium Borate (BBO) crystals in useful sizes at acceptable market prices, the promise of Optical Parametric Oscillators (OPOs) becoming practical tunable systems is finally being realized. Wavelength coverage from such systems extends from 420 nm to over 2400 nm when pumped in the UV. For medical applications their usage will be limited in the near term to low repetition rates (< 50 Hz) nanosecond pulsed systems. The pump lasers of choice will be flashlamp pumped Q-switched Nd:YAG lasers. As higher repetition rate (kHz) Q-switched diode pumped solid state continue to increase in energy and decrease in price, they are likely to also become viable pump sources for lower energy OPO systems. Energy output in excess of 100 mJ from low repetition rate OPO systems may make them suitable for selective absorption applications in medicine such as colored tattoo removal or treating vascular lesions. For such high energy devices peak powers necessitate the use of articulating arms for beam delivery. For high repetition rate systems, energy outputs will be in the range of 100 to 500 (mu) J at kHz frequencies (up to 1 W average power). Peak powers are low enough that fiber optic delivery is possible. These systems may find selective absorption applications in ophthalmology.

  7. An expanded porphyrin approach toward transactinium chelation and the development of porphyrin-coated optical fibers as potential actinide sensors

    SciTech Connect

    Klunder, G.; Silva, R.

    1994-12-01

    Characterization of the contamination at DOE waste sites and facilities is necessary during environmental restoration. Characterization of toxic waste in containers and storage tanks is needed for effective waste management. Therefore, analytical and monitoring systems are needed for real-time analysis and feedback. The development of in-situ methods to measure chemical properties by specialized instrumentation capable of real-time analysis, without sacrificing sensitivity, has been identified as an area of needed development. Absorption spectroscopy is widely used and considered to be one of the most reliable techniques available for the qualitative and quantitative determination of sample composition. With the advancements in fiber optic technology, using light for remote in-situ sensing of groundwater contaminants has become practical. Significant progress has been made in the area of fiber-optic chemical sensors as can be seen by the number of recent review articles. The objective of this work is to develop a remote sensor for real-time measurement of actinides and concentrations in environmental or process waters based on absorption spectroscopy using internal reflection spectroscopy. Porphyrin coated silica wafers were prepared and the sensitivity and selectivity to actinides was determined.

  8. Review of doped silica glass optical fibre: their TL properties and potential applications in radiation therapy dosimetry.

    PubMed

    Bradley, D A; Hugtenburg, R P; Nisbet, A; Abdul Rahman, Ahmad Taufek; Issa, Fatma; Mohd Noor, Noramaliza; Alalawi, Amani

    2012-12-01

    Review is made of dosimetric studies of Ge-doped SiO(2) telecommunication fibre as a 1-D thermoluminescence (TL) system for therapeutic applications. To-date, the response of these fibres has been investigated for UV sources, superficial X-ray beam therapy facilities, a synchrotron microbeam facility, electron linear accelerators, protons, neutrons and alpha particles, covering the energy range from a few eV to several MeV. Dosimetric characteristics include, reproducibility, fading, dose response, reciprocity between TL yield and dose-rate and energy dependence. The fibres produce a flat response to fixed photon and electron doses to within better than 3% of the mean TL distribution. Irradiated Ge-doped SiO(2) optical fibres show limited signal fading, with an average loss of TL signal of ~0.4% per day. In terms of dose response, Ge-doped SiO(2) optical fibres have been shown to provide linearity to x and electron doses, from a fraction of 1 Gy up to 2 kGy. The dosimeters have also been used in measuring photoelectron generation from iodinated contrast media; TL yields being some 60% greater in the presence of iodine than in its absence. The review is accompanied by previously unpublished data. Copyright © 2012 Elsevier Ltd. All rights reserved.

  9. Optical and structural properties of down-conversion Bi doped Y2O3 films for potential application in solar cell

    NASA Astrophysics Data System (ADS)

    Meng, Lijian; Xu, Wei; Zhang, Qingyu

    2017-07-01

    The highly efficient antireflective down-conversion Bi-doped Y2O3 films have been deposited on the (100) oriented Si and quartz substrates by rf reactive magnetron sputtering using a metallic target. The effects of the Bi doping concentration on the optical and structural properties of the films were studied. The Bi/Y ratio in the films varied from 0.002 to 0.02. The undoped Y2O3 films show a cubic phase crystal structure with a preferred orientation along the (222) direction. Bi doping results in the appearance of the (111) oriented monoclinic phase crystal structure. The refractive index is increased and the optical band gap is decreased as the Bi concentration in the films is increased. The bright green photoluminescence of Bi ions was observed under ultraviolet light excitation for all the Bi-doped Y2O3 films and the luminescence intensity increases as the Bi/Y ratio is increased from 0.002 to 0.02. In addition, Bi-doped Y2O3 films show a much lower optical reflectance than the undoped Y2O3 films. These results make the Bi-doped Y2O3 films a potential application not only as a spectrum converting layer but also as an antireflective layer in crystalline Si solar cells.

  10. Integrated optics technology study

    NASA Technical Reports Server (NTRS)

    Chen, B.; Findakly, T.; Innarella, R.

    1982-01-01

    The status and near term potential of materials and processes available for the fabrication of single mode integrated electro-optical components are discussed. Issues discussed are host material and orientation, waveguide formation, optical loss mechanisms, wavelength selection, polarization effects and control, laser to integrated optics coupling fiber optic waveguides to integrated optics coupling, sources, and detectors. Recommendations of the best materials, technology, and processes for fabrication of integrated optical components for communications and fiber gyro applications are given.

  11. Experimental Glaucoma Causes Optic Nerve Head Neural Rim Tissue Compression: A Potentially Important Mechanism of Axon Injury

    PubMed Central

    Fortune, Brad; Reynaud, Juan; Hardin, Christy; Wang, Lin; Sigal, Ian A.; Burgoyne, Claude F.

    2016-01-01

    Purpose We tested the hypothesis that experimental glaucoma (EG) results in greater thinning of the optic nerve head (ONH) neural rim tissue than the peripapillary retinal nerve fiber layer (RNFL) tissue. Methods Longitudinal spectral-domain optical coherence tomography (SDOCT) imaging of the ONH and peripapillary RNFL was performed every other week under manometric IOP control (10 mm Hg) in 51 nonhuman primates (NHP) during baseline and after induction of unilateral EG. The ONH parameter minimum rim area (MRA) was derived from 80 radial B-scans centered on the ONH; RNFL cross-sectional area (RNFLA) from a peripapillary circular B-scan with 12° diameter. Results In control eyes, MRA was 1.00 ± 0.19 mm2 at baseline and 1.00 ± 0.19 mm2 at the final session (P = 0.77), while RNFLA was 0.95 ± 0.09 and 0.95 ± 0.10 mm2, respectively (P = 0.96). In EG eyes, MRA decreased from 1.00 ± 0.19 mm2 at baseline to 0.63 ± 0.21 mm2 at the final session (P < 0.0001), while RNFLA decreased from 0.95 ± 0.09 to 0.74 ± 0.19 mm2, respectively (P < 0.0001). Thus, MRA decreased by 36.4 ± 20.6% in EG eyes, significantly more than the decrease in RNFLA (21.7 ± 19.4%, P < 0.0001). Other significant changes in EG eyes included increased Bruch's membrane opening (BMO) nonplanarity (P < 0.05), decreased BMO aspect ratio (P < 0.0001), and decreased MRA angle (P < 0.001). Bruch's membrane opening area did not change from baseline in either control or EG eyes (P = 0.27, P = 0.15, respectively). Conclusions Optic nerve head neural rim tissue thinning exceeded peripapillary RNFL thinning in NHP EG. These results support the hypothesis that axon bundles are compressed transversely within the ONH rim along with glaucomatous deformation of connective tissues. PMID:27564522

  12. Review of the potential of optical technologies for cancer diagnosis in neurosurgery: a step toward intraoperative neurophotonics.

    PubMed

    Vasefi, Fartash; MacKinnon, Nicholas; Farkas, Daniel L; Kateb, Babak

    2017-01-01

    Advances in image-guided therapy enable physicians to obtain real-time information on neurological disorders such as brain tumors to improve resection accuracy. Image guidance data include the location, size, shape, type, and extent of tumors. Recent technological advances in neurophotonic engineering have enabled the development of techniques for minimally invasive neurosurgery. Incorporation of these methods in intraoperative imaging decreases surgical procedure time and allows neurosurgeons to find remaining or hidden tumor or epileptic lesions. This facilitates more complete resection and improved topology information for postsurgical therapy (i.e., radiation). We review the clinical application of recent advances in neurophotonic technologies including Raman spectroscopy, thermal imaging, optical coherence tomography, and fluorescence spectroscopy, highlighting the importance of these technologies in live intraoperative tissue mapping during neurosurgery. While these technologies need further validation in larger clinical trials, they show remarkable promise in their ability to help surgeons to better visualize the areas of abnormality and enable safe and successful removal of malignancies.

  13. Magnetic switching of optical reflectivity in nanomagnet/micromirror suspensions: colloid displays as a potential alternative to liquid crystal displays.

    PubMed

    Bubenhofer, S B; Athanassiou, E K; Grass, R N; Koehler, F M; Rossier, M; Stark, W J

    2009-12-02

    Two-particle colloids containing nanomagnets and microscale mirrors can be prepared from iron oxide nanoparticles, microscale metal flakes and high-density liquids stabilizing the mirror suspension against sedimentation by matching the constituent's density. The free Brownian rotation of the micromirrors can be magnetically controlled through an anisotropic change in impulse transport arising from impacts of the magnetic nanoparticles onto the anisotropic flakes. The resulting rapid mirror orientation allows large changes in light transmission and switchable optical reflectivity. The preparation of a passive display was conceptually demonstrated through colloid confinement in a planar cavity over an array of individually addressable solenoids and resulted in 4 x 4 digit displays with a reaction time of less than 100 ms.

  14. Symmetry energy, its density slope, and neutron-proton effective mass splitting at normal density extracted from global nucleon optical potentials

    SciTech Connect

    Xu Chang; Li Baoan; Chen Liewen

    2010-11-15

    Based on the Hugenholtz-Van Hove theorem, it is shown that both the symmetry energy E{sub sym}({rho}) and its density slope L({rho}) at normal density {rho}{sub 0} are completely determined by the nucleon global optical potentials. The latter can be extracted directly from nucleon-nucleus scatterings, (p,n) charge-exchange reactions, and single-particle energy levels of bound states. Averaging all phenomenological isovector nucleon potentials constrained by world data available in the literature since 1969, the best estimates of E{sub sym}({rho}{sub 0})=31.3 MeV and L({rho}{sub 0})=52.7 MeV are simultaneously obtained. Moreover, the corresponding neutron-proton effective mass splitting in neutron-rich matter of isospin asymmetry {delta} is estimated to be (m{sub n}{sup *}-m{sub p}{sup *})/m=0.32{delta}.

  15. Dual optical recordings for action potentials and calcium handling in induced pluripotent stem cell models of cardiac arrhythmias using genetically encoded fluorescent indicators.

    PubMed

    Song, LouJin; Awari, Daniel W; Han, Elizabeth Y; Uche-Anya, Eugenia; Park, Seon-Hye E; Yabe, Yoko A; Chung, Wendy K; Yazawa, Masayuki

    2015-05-01

    Reprogramming of human somatic cells to pluripotency has been used to investigate disease mechanisms and to identify potential therapeutics. However, the methods used for reprogramming, in vitro differentiation, and phenotyping are still complicated, expensive, and time-consuming. To address the limitations, we first optimized a protocol for reprogramming of human fibroblasts and keratinocytes into pluripotency using single lipofection and the episomal vectors in a 24-well plate format. This method allowed us to generate multiple lines of integration-free and feeder-free induced pluripotent stem cells (iPSCs) from seven patients with cardiac diseases and three controls. Second, we differentiated human iPSCs derived from patients with Timothy syndrome into cardiomyocytes using a monolayer differentiation method. We found that Timothy syndrome cardiomyocytes showed slower, irregular contractions and abnormal calcium handling compared with the controls. The results are consistent with previous reports using a retroviral method for reprogramming and an embryoid body-based method for cardiac differentiation. Third, we developed an efficient approach for recording the action potentials and calcium transients simultaneously in control and patient cardiomyocytes using genetically encoded fluorescent indicators, ArcLight and R-GECO1. The dual optical recordings enabled us to observe prolonged action potentials and abnormal calcium handling in Timothy syndrome cardiomyocytes. We confirmed that roscovitine rescued the phenotypes in Timothy syndrome cardiomyocytes and that these findings were consistent with previous studies using conventional electrophysiological recordings and calcium imaging with dyes. The approaches using our optimized methods and dual optical recordings will improve iPSC applicability for disease modeling to investigate mechanisms underlying cardiac arrhythmias and to test potential therapeutics.

  16. Application of optical action potentials in human induced pluripotent stem cells-derived cardiomyocytes to predict drug-induced cardiac arrhythmias.

    PubMed

    Lu, H R; Hortigon-Vinagre, M P; Zamora, V; Kopljar, I; De Bondt, A; Gallacher, D J; Smith, G

    2017-09-01

    Human induced pluripotent stem cell-derived cardiomyocytes (hiPS-CMs) are emerging as new and human-relevant source in vitro model for cardiac safety assessment that allow us to investigate a set of 20 reference drugs for predicting cardiac arrhythmogenic liability using optical action potential (oAP) assay. Here, we describe our examination of the oAP measurement using a voltage sensitive dye (Di-4-ANEPPS) to predict adverse compound effects using hiPS-CMs and 20 cardioactive reference compounds. Fluorescence signals were digitized at 10kHz and the records subsequently analyzed off-line. Cells were exposed to 30min incubation to vehicle or compound (n=5/dose, 4 doses/compound) that were blinded to the investigating laboratory. Action potential parameters were measured, including rise time (Trise) of the optical action potential duration (oAPD). Significant effects on oAPD were sensitively detected with 11 QT-prolonging drugs, while oAPD shortening was observed with ICa-antagonists, IKr-activator or ATP-sensitive K(+) channel (KATP)-opener. Additionally, the assay detected varied effects induced by 6 different sodium channel blockers. The detection threshold for these drug effects was at or below the published values of free effective therapeutic plasma levels or effective concentrations by other studies. The results of this blinded study indicate that OAP is a sensitive method to accurately detect drug-induced effects (i.e., duration/QT-prolongation, shortening, beat rate, and incidence of early after depolarizations) in hiPS-CMs; therefore, this technique will potentially be useful in predicting drug-induced arrhythmogenic liabilities in early de-risking within the drug discovery phase. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. Potentials of Optical Damage Assessment Techniques in Automotive Crash-Concepts composed of FRP-Steel Hybrid Material Systems

    NASA Astrophysics Data System (ADS)

    Dlugosch, M.; Spiegelhalter, B.; Soot, T.; Lukaszewicz, D.; Fritsch, J.; Hiermaier, S.

    2017-05-01

    With car manufacturers simultaneously facing increasing passive safety and efficiency requirements, FRP-metal hybrid material systems are one way to design lightweight and crashworthy vehicle structures. Generic automotive hybrid structural concepts have been tested under crash loading conditions. In order to assess the state of overall damage and structural integrity, and primarily to validate simulation data, several NDT techniques have been assessed regarding their potential to detect common damage mechanisms in such hybrid systems. Significant potentials were found particularly in combining 3D-topography laser scanning and X-Ray imaging results. Ultrasonic testing proved to be limited by the signal coupling quality on damaged or curved surfaces.

  18. Subsea downhole optical sensing

    NASA Astrophysics Data System (ADS)

    McStay, D.; Shiach, G.; McAvoy, S.

    2009-07-01

    The potential for subsea downhole optical fibre sensing to optimize hydrocarbon production and hence contribute to enhanced oil recovery is described. The components of susbea downhole optical sensing systems are reviewed and the performance of a new subsea optical fibre feed-through for downhole optical fibre sensing reported.

  19. Transformation optics and metamaterials

    NASA Astrophysics Data System (ADS)

    Chen, Huanyang; Chan, C. T.; Sheng, Ping

    2010-05-01

    Underpinned by the advent of metamaterials, transformation optics offers great versatility for controlling electromagnetic waves to create materials with specially designed properties. Here we review the potential of transformation optics to create functionalities in which the optical properties can be designed almost at will. This approach can be used to engineer various optical illusion effects, such as the invisibility cloak.

  20. In Vivo therapeutic potential of mesenchymal stem cell-derived extracellular vesicles with optical imaging reporter in tumor mice model

    PubMed Central

    Kalimuthu, Senthilkumar; Gangadaran, Prakash; Li, Xiu Juan; Oh, Ji Min; Lee, Ho Won; Jeong, Shin Young; Lee, Sang-Woo; Lee, Jaetae; Ahn, Byeong-Cheol

    2016-01-01

    Mesenchymal stem cells (MSCs) can be used as a therapeutic armor for cancer. Extracellular vesicles (EVs) from MSCs have been evaluated for anticancer effects. In vivo targeting of EVs to the tumor is an essential requirement for successful therapy. Therefore, non-invasive methods of monitoring EVs in animal models are crucial for developing EV-based cancer therapies. The present study to develop bioluminescent EVs using Renilla luciferase (Rluc)-expressing MSCs. The EVs from MSC/Rluc cells (EV-MSC/Rluc) were visualized in a murine lung cancer model. The anticancer effects of EVs on Lewis lung carcinoma (LLC) and other cancer cells were assessed. EV-MSC/Rluc were visualized in vivo in the LLC-efffuc tumor model using optical imaging. The induction of apoptosis was confirmed with Annexin-V and propidium iodide staining. EV-MSC/Rluc and EV-MSCs showed a significant cytotoxic effect against LLC-effluc cells and 4T1; however, no significant effect on CT26, B16F10, TC1 cells. Moreover, EV-MSC/Rluc inhibited LLC tumor growth in vivo. EV-MSC/Rluc-mediated LLC tumor inhibitory mechanism revealed the decreased pERK and increased cleaved caspase 3 and cleaved PARP. We successfully developed luminescent EV-MSC/Rluc that have a therapeutic effect on LLC cells in both in vitro and in vivo. This bioluminescent EV system can be used to optimize EV-based therapy. PMID:27452924

  1. Combining red and blue-detuned optical potentials to form a Lamb-Dicke trap for a single neutral atom.

    PubMed

    He, Xiaodong; Yu, Shi; Xu, Peng; Wang, Jin; Zhan, Mingsheng

    2012-02-13

    We propose and demonstrate a scheme for strong radial confinement of a single 87 Rb atom by a bichromatic far-off resonance optical dipole trap (BFORT). The BFORT is composed of a blue-detuned Laguerre-Gaussian LG01 beam and a red-detuned Gaussian beam. The atomic oscillation frequency measurement shows that the effective trapping dimension is much sharper than that from a diffraction-limited microscopic objective. Theory shows that the added scattering rate due to imposing blue-detuned light is negligible when the temperature of the single atoms is close to ground state temperature. By carrying out sub-Doppler cooling, the mean energy of single atoms trapped in the BFORT is reduced to 15 ± 1 μK. The corresponding mean quantum number of radial vibration n is about 1.65, which satisfies the Lamb-Dicke regime. We conclude that the BFORT is a suitable Lamb-Dicke trap for further cooling a single neutral atom down to the ground state and for further application in quantum information processing.

  2. Growth, structural, optical and mechanical studies on acid mixed glycine metal salt (GABN) crystal as potential NLO material

    NASA Astrophysics Data System (ADS)

    Khandpekar, Mahendra M.; Dongare, Shailesh S.; Patil, Shirish B.; Pati, Shankar P.

    2012-03-01

    Transparent crystals of α-glycine with ammonium nitrate and barium nitrate (GABN) have been grown from aqueous solution by slow evaporation technique at room temperature. Crystals of size 11 × 7 × 4 mm 3 have been obtained in about 3-4 weeks time. The solubility of GABN has been determined in water. The grown crystal belongs to orthorhombic system with cell parameters a = 7.317 A.U, b = 12.154 A.U and c = 5.468 A.U with a unit cell volume 486.35 (A.U) 3. The presence of chemical components/groups has been identified by CHN, EDAX and NMR analysis. Comparative IR and Raman studies indicate a molecule with a lack of centre of symmetry. A wide transparency window useful for optoelectronic applications is indicated by the UV Studies. Using a Nd-YAG laser (1064 nm), the optical second harmonic generation (SHG) conversion efficiency of GABN is found to be 1.406 times of that of standard KDP. On exposure to light the GABN crystals are found to exhibit negative photoconductivity. I-V characteristics, SEM studies, dielectrics studies, and Vickers micro hardness measurement have been carried out.

  3. ELECTROMAGNETISM, OPTICS, ACOUSTICS, HEAT TRANSFER, CLASSICAL MECHANICS, AND FLUID DYNAMICS: Symmetry Analysis of Barotropic Potential Vorticity Equation

    NASA Astrophysics Data System (ADS)

    Bihlo, Alexander; Popovych, Roman O.

    2009-10-01

    Recently F. Huang [Commun. Theor. Phys. 42 (2004) 903] and X. Tang and P.K. Shukla [Commun. Theor. Phys. 49 (2008) 229] investigated symmetry properties of the barotropic potential vorticity equation without forcing and dissipation on the beta-plane. This equation is governed by two dimensionless parameters, F and β, representing the ratio of the characteristic length scale to the Rossby radius of deformation and the variation of earth' angular rotation, respectively. In the present paper it is shown that in the case F ≠ 0 there exists a well-defined point transformation to set β = 0. The classification of one- and two-dimensional Lie subalgebras of the Lie symmetry algebra of the potential vorticity equation is given for the parameter combination F ≠ 0 and β = 0. Based upon this classification, distinct classes of group-invariant solutions are obtained and extended to the case β ≠ 0.

  4. Optical Firmware

    NASA Technical Reports Server (NTRS)

    Bergman, Larry A.

    1989-01-01

    Data-processing system exploits high speeds inherent in optical elements. Instruction sets for different computer operations reside on different external memory chips. Laser diodes activated for each operation generate light, reflected by holographic optical element to designated receptors in arithmetic and logic unit. Pattern of light beams embodies instruction set at given instant. With potential ability to reprogram in real time, conceptual system applicable to task-driven programming or artificial intelligence.

  5. Non-centrosymmetric crystals of new N-benzylideneaniline derivatives as potential materials for non-linear optics.

    PubMed

    Souza, Talita Evelyn; Rosa, Iara Maria Landre; Legendre, Alexandre Oliveira; Paschoal, Diego; Maia, Lauro J Q; Dos Santos, Hélio F; Matins, Felipe Terra; Doriguetto, Antonio Carlos

    2015-08-01

    Three new N-benzylideneaniline derivatives [p-nitrobenzylidene-p-phenylamineaniline (I), 2,4-dinitrobenzylidene-p-phenylamineaniline (II) and p-dinitrobenzylidene-p-diethylamineaniline (III)] containing electron-push-pull groups have been prepared. They present a planar N-benzylideneaniline core and neighbouring functional atoms, which are related through an efficient intramolecular charge transfer (CT). Two of the derivatives crystallize in non-centrosymmetric space groups, a necessary condition for non-linear optical (NLO) responses. The NLO properties were calculated for the molecular conformations determined by single-crystal X-ray diffraction as well as for the four molecules packed into each corresponding unit cell, using a quantum-chemical method at the cam-B3LYP/NLO-V level of theory. As expected from antiparallel face-to-face stacking through centrosymmetry, the main NLO descriptors - namely, the first hyperpolarizability (βtot) and its projection on the dipole moment direction (βvec) - are almost zero for the tetramer of derivative III. Interestingly, the calculated first hyperpolarizability decreases in the non-centrosymmetric unit-cell content of derivative II when compared to its single molecule, which may be related to its molecular pillaring, similar to that observed in derivative III. On the other hand, a desirable magnification of the NLO properties was found for packed units of derivative I, which may be a consequence of its parallel face-to-tail stacking with the CT vectors of all molecules pointing in the same direction. Moreover, the CT vector of compound I makes an angle of θ = 33.6° with its crystal polar axis, resulting in a higher-order parameter (cos(3)θ = 0.6) compared with the other derivatives. This is in line with the higher macroscopic second-order NLO response predicted for derivative I, βtot = 120.4 × 10(-30) e.s.u.

  6. Automated in situ observations of upper ocean biogeochemistry, bio-optics, and physics and their potential use for global studies

    NASA Technical Reports Server (NTRS)

    Dickey, Tommy D.; Granata, Timothy C.; Taupier-Letage, Isabelle

    1992-01-01

    The processes controlling the flux of carbon in the upper ocean have dynamic ranges in space and time of at least nine orders of magnitude. These processes depend on a broad suite of inter-related biogeochemical, bio-optical, and physical variables. These variables should be sampled on scales matching the relevant phenomena. Traditional ship-based sampling, while critical for detailed and more comprehensive observations, can span only limited portions of these ranges because of logistical and financial constraints. Further, remote observations from satellite platforms enable broad horizontal coverage which is restricted to the upper few meters of the ocean. For these main reasons, automated subsurface measurement systems are important for the fulfillment of research goals related to the regional and global estimation and modeling of time varying biogeochemical fluxes. Within the past few years, new sensors and systems capable of autonomously measuring several of the critical variables have been developed. The platforms for deploying these systems now include moorings and drifters and it is likely that autonomous underwater vehicles (AUV's) will become available for use in the future. Each of these platforms satisfies particular sampling needs and can be used to complement both shipboard and satellite observations. In the present review, (1) sampling considerations will be summarized, (2) examples of data obtained from some of the existing automated in situ sampling systems will be highlighted, (3) future sensors and systems will be discussed, (4) data management issues for present and future automated systems will be considered, and (5) the status of near real-time data telemetry will be outlined. Finally, we wish to make it clear at the outset that the perspectives presented here are those of the authors and are not intended to represent those of the United States JGOFS program, the International JGOFS program, NOAA's C&GC program, or other global ocean programs.

  7. Neuropathies of the optic nerve and visual evoked potentials with special reference to color vision and differential light threshold measured with the computer perimeter OCTOPUS.

    PubMed

    Wildberger, H

    1984-10-31

    The contrast evoked potentials (VEPs) to different check sizes were recorded in about 200 cases of discrete optic neuropathies (ON) of different origin. Differential light threshold (DLT) was tested with the computer perimeter OCTOPUS. Saturated and desaturated tests were applied to evaluate the degree of acquired color vision deficiency. Delayed VEP responses are not confined to optic neuritis (RBN) alone and the different latency times obtained from other ON are confluent. The delay may be due to demyelination, to an increasing dominance of paramacular VEP subcomponents or to an increasing dominance of the upper half-field responses. Recording with smaller check sizes has the advantage that discrete dysfunctions in the visual field (VF) center are more easily detected: a correlation between amplitudes and visual acuity is best in strabismic amblyopias, is less expressed in maculopathies of the retina and weak in ON. The absence or reduction of amplitudes to smaller check sizes, however, is an important indication of a disorder in the VF center of ON in an early or recovered stage. Acquired color vision defects of the tritan-like type are more confined to discrete ON, whereas the red/green type is reserved to more severe ON. The DLT of the VF center is reduced in a different, significant and non significant extent in discrete optic neuropathies and the correlation between DLT and visual acuity is weak. A careful numerical analysis is needed in types of discrete ON where the central DLT lies within normal statistical limits: a side difference of the DLT between the affected and the normal fellow eye is always present. Evaluation of visual fatigue effects and of the relative sensitivity loss of VF center and VF periphery may provide further diagnostic information.

  8. Integrated Optical Information Processing

    DTIC Science & Technology

    1988-08-01

    dimensional processing to be performed with inherently one-dimensional signal processing devices. This permits the monolithic or hybrid integration of...effective time delays; 5. Selective partial waveguide outcoupling of channelized light from an integrated optical chip; 6. Potential monolithic ... integrated optical chip; 6. Potential monolithic integration of optical waveguides with two-dimensional opto- electronic detector technology. The integrated

  9. Comparison of multifocal visual evoked potential, standard automated perimetry and optical coherence tomography in assessing visual pathway in multiple sclerosis patients

    PubMed Central

    Laron, Michal; Cheng, Han; Zhang, Bin; Schiffman, Jade S.; Tang, Rosa A.; Frishman, Laura J.

    2010-01-01

    Background Multifocal visual evoked potentials (mfVEP) measure local response amplitude and latency in the field of vision Objective To compare the sensitivity of mfVEP, Humphrey visual field (HVF) and optical coherence tomography (OCT) in detecting visual abnormality in multiple sclerosis (MS) patients. Methods MfVEP, HVF, and OCT (retinal nerve fiber layer [RNFL]) were performed in 47 MS-ON eyes (last optic neuritis (ON) attack ≥ 6 months prior) and 65 MS-no-ON eyes without ON history. Criteria to define an eye as abnormal were: mfVEP 1) amplitude/latency: either amplitude or latency probability plots meeting cluster criteria with 95% specificity 2) amplitude or latency alone (specificity: 97% and 98%, respectively); HVF and OCT, mean deviation and RNFL thickness meeting p < 0.05, respectively. Results MfVEP (amplitude/latency) identified more abnormality in MS-ON eyes (89%) than HVF (72%), OCT (62%), mfVEP amplitude (66%) or latency (67%) alone. 18% of MS-no-ON eyes were abnormal for both mfVEP (amplitude/latency) and HVF compared to 8% with OCT. Agreement between tests ranged from 60% to 79%. MfVEP (amplitude/latency) categorized an additional 15% of MS-ON eyes as abnormal compared to HVF and OCT combined. Conclusions MfVEP, which detects both demyelination (increased latency) and neural degeneration (reduced amplitude) revealed more abnormality than HVF or OCT in MS patients. PMID:20207786

  10. Band gap engineering and optical response of the ACr2S4 (A=Fe, Co) normal spinels using PBE+U and TB-mBJ potentials

    NASA Astrophysics Data System (ADS)

    Samanta, Saurabh; Saini, Sapan Mohan

    2017-03-01

    The electronic and optical properties of the ACr2S4 (A=Fe, Co) normal spinels have been studied by use of the full-potential linearized augmented plane wave (FPLAPW) method based on density functional theory (DFT). The calculations were performed by two methods, namely, PBE+U and TB-mBJ, with the addition of spin-orbit coupling in both the schemes. The lattice constant and internal parameter of unit cell were optimized. Band structure obtained are analysed based on Density of States (DOS). We found that more pronounced splitting of A-d and Cr-d states in TB-mBJ scheme is responsible for the larger band gaps. The octahedral field surrounding Cr-atoms splits the Cr-d levels into t2g and eg states with some mixing between the two states. The calculated values of spin magnetic moment per formula unit are consistent with earlier report. Optical properties are calculated along the directions of lattice constants to analyze their anisotropic nature based on energy level transitions. We also studied the refractive index, n (ω), and the extinction coefficient, k (ω), by PBE+U and TB-mBJ scheme.

  11. Optical and electrostatic potential investigations of electrical breakdown phenomena in a low-pressure gas discharge lamp

    NASA Astrophysics Data System (ADS)

    Gendre, M. F.; Haverlag, M.; Kroesen, G. M. W.

    2010-06-01

    The ignition phase is a critical stage in the operation of gas discharge lamps where the neutral gas enclosed between the electrodes undergoes a transformation from the dielectric state to a conducting phase, eventually enabling the production of light. The phenomena occurring during this phase transition are not fully understood and the related experimental studies are often limited to local optical measurements in environments prone to influencing these transient phenomena. In this work unipolar ignition phenomena at sub-kilovolt levels are investigated in a 3 Torr argon discharge tube. The lamp is placed in a highly controlled environment so as to prevent any bias on the measurements. A fast intensified CCD camera and a specially designed novel electrostatic probe are used simultaneously so as to provide a broad array of measured and computed parameters which are displayed in space-time diagrams for cross comparisons. Experiments show that three distinct phases exist during successful ignitions: upon the application of voltage a first ionization wave starts from the active electrode and propagates in the neutral gas towards the opposite electrode. A local front of high axial E field strength is associated with this process and causes a local ionization to occur, leading to the electrostatic charging of the lamp. Next, a second wave propagates from the ground electrode back towards the active electrode with a higher velocity, and in this process leads to a partial discharging of the lamp. This return stroke draws a homogeneous plasma column which eventually bridges both electrodes at the end of the wave propagation. At this point both electrode sheaths are formed and the common features of a glow discharge are observed. The third phase is an increase in the light intensity of the plasma column until the lamp reaches a steady-state operation. Failed ignitions present only the first phase where the first wave starts its propagation but extinguishes in the lamp

  12. Optical Response of Mixed Molybdenum Dichalcogenides for Solar Cell Applications Using the Modified Becke-Johnson Potential

    NASA Astrophysics Data System (ADS)

    Ahuja, Ushma; Joshi, Ritu; Kothari, D. C.; Tiwari, Harpal; Venugopalan, K.

    2016-03-01

    Energy bands and density of states (DOS) of mixed molybdenum dichalcogenides like MoS2, MoSeS, MoSe2, MoTe2, MoTeS, and MoTe0.5S1.5 are reported for the first time using the Tran-Blaha modified Becke-Johnson potential within full potential-linearised augmented plane wave technique. From the partial DOS, a strong hybridisation between the Mo-d and chalcogen-p states is observed below the Fermi energy EF. In addition, the dielectric constants, absorption coefficients, and refractivity spectra of these compounds have also been deduced. The integrated absorption coefficients derived from the frequency-dependent absorption spectra within the energy range of 0-4.5 eV show a possibility of using molybdenum dichalcogenides, particularly MoTe0.5S1.5, in solar cell applications. Birefringence and degree of anisotropy are also discussed using the data on refractivity and imaginary components of the dielectric constant.

  13. Estimation of the Breakup Cross-Sections in 6He + 12C Reaction Within High-Energy Approximation and Microscopic Optical Potential

    NASA Astrophysics Data System (ADS)

    Lukyanov, V. K.; Zemlyanaya, E. V.; Lukyanov, K. V.

    The breakup cross-sections in the reaction 6He + 12C are calculated at about 40 MeV/nucleon using the high-energy approximation (HEA) and with the help of microscopic optical potentials (OP) of interaction with the target nucleus 12C of the projectile nucleus fragments 4He and 2n. Considering the di-neutron h = 2n as a single particle the relative motion hα wave function is estimated so that to explain both the separation energy of h in 6He and the rms radius of the latter. The stripping and absorbtion total cross-sections are calculated and their sum is compared with the total reaction cross-section obtained within a double-folding microscopic OP for the 6He + 12C scattering. It is concluded that the breakup cross-sections contribute to about 50% of the total reaction cross-section.

  14. Broadband 1.53 μm emission property in Er3+ doped germa-silicate glass for potential optical amplifier

    NASA Astrophysics Data System (ADS)

    Wei, Tao; Chen, Fangze; Tian, Ying; Xu, Shiqing

    2014-03-01

    In this paper, a new type of germa-silicate glass was developed. A detailed investigation of thermal stability, absorption spectrum and 1.53 μm emission spectrum was carried out. Based on the absorption spectrum and Judd-Ofelt theory, the Judd-Ofelt parameters and radiative properties were calculated and compared to other glasses. The thermal stability of prepared glass can reach as high as 155 °C. Er3+ doped germa-silicate glass possessing high full-width at half-maximum (FWHM) (77 nm) and large stimulated emission cross-section (9.55×10-21 cm2) shows its potential application in broadband optical amplifier.

  15. Exploring the potential of optical remote sensing for oil spill detection in shallow coastal waters--a case study in the Arabian Gulf.

    PubMed

    Zhao, Jun; Temimi, Marouane; Ghedira, Hosni; Hu, Chuanmin

    2014-06-02

    Remote sensing provides an effective tool for timely oil pollution response. In this paper, the spectral signature in the optical and infrared domains of oil slicks observed in shallow coastal waters of the Arabian Gulf was investigated with MODIS, MERIS, and Landsat data. Images of the Floating Algae Index (FAI) and estimates of sea currents from hydrodynamic models supported the multi-sensor oil tracking technique. Scenes with and without sunglint were studied as the spectral signature of oil slicks in the optical domain depends upon the viewing geometry and the solar angle in addition to the type of oil and its thickness. Depending on the combination of those factors, oil slicks may exhibit dark or bright contrasts with respect to oil-free waters. Three oil spills events were thoroughly analyzed, namely, those detected on May 26 2000 by Landsat 7 ETM + and MODIS/Terra, on October 21 2007 by MERIS and MODIS, and on August 17 2013 by Landsat 8 and MODIS/Aqua. The oil slick with bright contrast observed by Landsat 7 ETM + on May 26 2000 showed lower temperature than oil-free areas. The spectral Rayleigh-corrected reflectance (R(rc)) signature of oil-covered areas indicated higher variability due to differences in oil fractions while the R(rc) spectra of the oil-free area were persistent. Combined with RGB composites, FAI images showed potentials in differentiating oil slicks from algal blooms. Ocean circulation and wind data were used to track oil slicks and forecast their potential landfall. The developed oil spill maps were in agreement with official records. The synergistic use of satellite observations and hydrodynamic modeling is recommended for establishing an early warning and decision support system for oil pollution response.

  16. Integrated optics for fiber optic sensors

    NASA Technical Reports Server (NTRS)

    Minford, W. J.; Depaula, R. P.

    1991-01-01

    Recent progress achieved in the field of fiber-optic sensor applications is discussed with emphasis placed on LiNbO3-based integrated optics (IO). Particular consideration is given to advanced electromagnetic-field sensors, an integrated laser vibrometer system, and a fiber-optic gyroscope system. It is shown that the multifunction IO chips have enabled high perforamance fiber-optic sensors (e.g., fiber-optic gyros), provided advanced and unique signal processing capabilities and advanced architectures, and have a potential of making fiber-optic sensors at low cost.

  17. Integrated optics for fiber optic sensors

    NASA Technical Reports Server (NTRS)

    Minford, W. J.; Depaula, R. P.

    1991-01-01

    Recent progress achieved in the field of fiber-optic sensor applications is discussed with emphasis placed on LiNbO3-based integrated optics (IO). Particular consideration is given to advanced electromagnetic-field sensors, an integrated laser vibrometer system, and a fiber-optic gyroscope system. It is shown that the multifunction IO chips have enabled high perforamance fiber-optic sensors (e.g., fiber-optic gyros), provided advanced and unique signal processing capabilities and advanced architectures, and have a potential of making fiber-optic sensors at low cost.

  18. Ge and B doped collapsed photonic crystal optical fibre, a potential TLD material for low dose measurements

    NASA Astrophysics Data System (ADS)

    Rozaila, Z. Siti; Alyahyawi, Amjad; Khandaker, M. U.; Amin, Y. M.; Bradley, D. A.; Maah, M. J.

    2016-09-01

    Offering a number of advantageous features, tailor-made silica-based fibres are attracting attention as thermoluminesence (TL) dosimeters. We have performed a detailed study of the TL properties of Ge-doped and Ge-B-doped collapsed photonic crystal fibres (PCFc), most particularly with regard to their potential use for the environmental and X-ray diagnostic dose monitoring. Extrinsic doping and defects generated by strain at the fused inner walls of the collapsed fibres result in the PCFc-Ge-B and PCFc-Ge fibres producing markedly greater TL response than that of the phosphor-based dosimeter TLD-100, by some 9 and 7×, respectively. The linearity of TL yield has been investigated for X-ray doses from 0.5 mGy to 10 mGy. For a dose of 1 Gy, the energy response of the PCFs and TLD-100 has been studied using X-rays generated at accelerating potentials from 20 kVp through to 200 kVp and for the 1.25 MeV mean gamma-ray energy from 60Co. The effective atomic number , Zeffof PCFc-Ge and PCFc-Ge-B was estimated to be 12.5 and 14.4, respectively. Some 35 days post-irradiation, fading of the stored TL signal from PCFc-Ge-B and PCFc-Ge were found to be ∼15% and 20% respectively, with mean loss in TL emission of 0.4-0.5% per day. The present doped-silica collapsed PCFs provide greatly improved TLD performance compared to that of previous fibre designs and phosphor-based TLD-100.

  19. Optical devices: A compilation

    NASA Technical Reports Server (NTRS)

    1976-01-01

    Technological developments in the field of optics devices which have potential utility outside the aerospace community are described. Optical instrumentation, light generation and transmission, and laser techniques are among the topics covered. Patent information is given.

  20. Optical coherence tomography imaging of telangiectasias during intense pulsed light treatment: a potential tool for rapid outcome assessment.

    PubMed

    Ring, Hans Christian; Mogensen, Mette; Banzhaf, Christina; Themstrup, Lotte; Jemec, Gregor B E

    2013-05-01

    Vascular malformations commonly occur in the facial region, and can be associated with significant stigma and embarrassment. Studies have shown that even recommended light-based treatments do not always result in complete clearance. This indicates the need for more accurate pre-treatment assessment of vessel morphology to optimize treatment settings and identify possible morphological predictors of the outcome. Fourteen patients (six males, eight females, and aged 37-66 years) with the diagnosis of telangiectasias were enrolled and were all scanned with OCT and digitally photographed before and minutes after IPL treatment. OCT images of the telangiectasias before treatment were displayed as hyporeflective/signal poor bands clearly demarcated from the surrounding tissue. Minutes after treatment, OCT images demonstrated two different reactions. (1) Narrow hyperreflective bands surrounding the vessels, which may indicate edema or insufficient coagulation. (2) Hyperreflective signals within the lumen of the vessels, compatible with the expected irreversible microthrombus formation in the vessels. OCT imaging is capable of real-time assessment of tissue damage during light and laser treatment, including visualization of the perivascular changes. This may offer a more dynamic, more complete understanding of the efficacy and potential outcome of the treatment process. It is hypothesized that these immediate changes may correlate to longer-term treatment outcome.

  1. Evaluation of optically acquired zooplankton size-spectrum data as a potential tool for assessment of condition in the Great Lakes.

    PubMed

    Yurista, Peder; Kelly, John R; Miller, Samuel

    2005-01-01

    An optical plankton counter (OPC) potentially provides an assessment tool for zooplankton condition in ecosystems that is rapid, economical, and spatially extensive. We collected zooplankton data with an OPC in 20 near-shore regions of 4 of the Laurentian Great Lakes. The zooplankton size information was used to compute mean size, biomass density, and size-spectra parameters for each location. The resulting metrics were analyzed for their ability to discriminate among the Great Lakes. Biomass density provided discrimination among lakes, as did several parameters describing spectra shape and distribution. A proposed zooplankton indicator, mean size (determined with OPC measurements in this study), was found to provide discrimination among lakes. Size-spectra-related parameters added increased ability to discriminate in conjunction with the biomass density (or mean size) metric. A discriminant function analysis of the multiple metrics (mean size, biomass density, and distribution parameters) suggests that a multi metric size-based approach might be used to classify communities among lakes improving a mean-size metric. The feasibility OPCs and size-based metrics for zooplankton assessment was found to have potential for further development as assessment tools for the biological condition of zooplankton communities in the Great Lakes.

  2. Determination of Gravitational Potential at Ground Using Optical-Atomic Clocks on Board Satellites and on Ground Stations and Relevant Simulation Experiments

    NASA Astrophysics Data System (ADS)

    Shen, Ziyu; Shen, Wen-Bin; Zhang, Shuangxi

    2017-07-01

    The general relativity theory provides a potential way to directly determine the gravitational potential (GP) difference by comparing the running rate or vibration frequencies of two optical-atomic clocks located at two stations. Recently we proposed an approach referred to as satellite frequency signal transmission based on the Doppler canceling technique or tri-frequency combination technique to determine the GP difference between a satellite and a ground site via exchanging microwave signals. Here, as an extension of our previous study, we aim to formulate determination of GP at ground stations and establish simulation experiments in different cases, including determining the GP at a ground station via one or more satellites and determining the GP difference between two ground stations via one or more satellites. Concerning each case we made simulating experiments, and results show that the precision of the GP at a ground station and that of the GP difference between two stations, determined via one satellite, are, respectively, about 0.383 and 0.454 m2/s2, assuming the clocks with inaccuracy of about 1× 10^{-18} (s/s) level are available. If more satellites equipped with ultra-high-precise clocks are available, the precision of the determined GP (difference) at ground stations can be further improved.

  3. Study of thermoluminescence (TL) and optically stimulated luminescence (OSL) from α-keratin protein found in human hairs and nails: potential use in radiation dosimetry.

    PubMed

    Mishra, D R; Soni, A; Rawat, N S; Bokam, G

    2016-05-01

    The thermoluminescence (TL) and optically stimulated luminescence (OSL) properties of human nails and hairs containing α-keratin proteins have been investigated. For the present studies, black hairs and finger nails were selectively collected from individuals with ages between 25 and 35 years. The collected hairs/nails were cut to a size of < 1 mm and cleaned with distilled water to remove dirt and other potential physical sources of contamination. All samples were optically beached with 470 nm of LED light at 60 mW/cm(2) intensity and irradiated by a (60)Co γ source. The hair and nail samples showed overlapping multiple TL glow peaks in the temperature range from 70 to 210 ° C. Continuous wave (CW)-OSL measurements of hair samples at a wavelength of 470 nm showed the presence of two distinct OSL components with photoionization cross section (PIC) values of about 1.65 × 10(-18) cm(2) and about 3.48 × 10(-19) cm(2), while measurements of nail samples showed PIC values of about 6.98 × 10(-18) cm(2) and about 8.7 × 10(-19) cm(2), respectively. This difference in PIC values for hair and nail samples from the same individual is attributed to different arrangement of α-keratin protein concentrations in the samples. The OSL sensitivity was found to vary ± 5 times among nail and hair samples from different individuals, with significant fading (60% in 11 h) at room temperature. The remaining signal (after fading) can be useful for dose estimation when a highly sensitive OSL reader is used. In the absorbed dose range of 100 mGy-100 Gy, both the TL and OSL signals of hair and nail samples showed linear dose dependence. The results obtained in the present study suggest that OSL using hair and nail samples may provide a supplementary method of dose estimation in radiological and nuclear emergencies.

  4. Optic glioma

    MedlinePlus

    Glioma - optic; Optic nerve glioma; Juvenile pilocytic astrocytoma; Brain cancer - optic glioma ... Optic gliomas are rare. The cause of optic gliomas is unknown. Most optic gliomas are slow-growing ...

  5. Optical properties of a biomimetically prepared hierarchical structured polydimethyl siloxane template for potential application in anti-reflection and photovoltaic encapsulation

    NASA Astrophysics Data System (ADS)

    Singh Bindra, Harsimran; Kiran Kumar, A. B. V.; Nayak, Ranu

    2017-05-01

    This paper describes optical studies on a polydimethyl siloxane (PDMS) surface biomimicked from rose petals. The textured PDMS membrane showed hierarchical nanostructures and significantly improved optical transmittance (96%; 400-1400 nm), and also indicated good superhydrophobic and self-cleaning properties. The average optical reflectance obtained was as low as 3% within a broad wavelength range of 400-1400 nm. Furthermore, an optical degradation analysis in the ambient atmosphere under varying weather conditions (46-4 °C) for a period of 12 months indicated a slow rate of decline in the optical properties of the hierarchical structured PDMS surface with negligible moisture permeation.

  6. Optical electronics

    NASA Technical Reports Server (NTRS)

    Javan, A.

    1976-01-01

    The development of an optical diode consisting of a metal-dielectric-metal junction in which the high-speed electric conduction process occurs due to quantum mechanical electron tunneling across the dielectric barrier is briefly reviewed. Potential applications of the diode are discussed.

  7. The Central Bright Spot Sign: A Potential New MR Imaging Sign for the Early Diagnosis of Anterior Ischemic Optic Neuropathy due to Giant Cell Arteritis.

    PubMed

    Remond, P; Attyé, A; Lecler, A; Lamalle, L; Boudiaf, N; Aptel, F; Krainik, A; Chiquet, C

    2017-07-01

    A rapid identification of the etiology of anterior ischemic optic neuropathy is crucial because it determines therapeutic management. Our aim was to assess MR imaging to study the optic nerve head in patients referred with anterior ischemic optic neuropathy, due to either giant cell arteritis or the nonarteritic form of the disease, compared with healthy subjects. Fifteen patients with giant cell arteritis-related anterior ischemic optic neuropathy and 15 patients with nonarteritic anterior ischemic optic neuropathy from 2 medical centers were prospectively included in our study between August 2015 and May 2016. Fifteen healthy subjects and patients had undergone contrast-enhanced, flow-compensated, 3D T1-weighted MR imaging. The bright spot sign was defined as optic nerve head enhancement with a 3-grade ranking system. Two radiologists and 1 ophthalmologist independently performed blinded evaluations of MR imaging sequences with this scale. Statistical analysis included interobserver agreement. MR imaging scores were significantly higher in patients with giant cell arteritis-related anterior ischemic optic neuropathy than in patients with nonarteritic anterior ischemic optic neuropathy (P ≤ .05). All patients with giant cell arteritis-related anterior ischemic optic neuropathy (15/15) and 7/15 patients with nonarteritic anterior ischemic optic neuropathy presented with the bright spot sign. No healthy subjects exhibited enhancement of the anterior part of the optic nerve. There was a significant relationship between the side of the bright spot and the side of the anterior ischemic optic neuropathy (P ≤ .001). Interreader agreement was good for observers (κ = 0.815). Here, we provide evidence of a new MR imaging sign that identifies the acute stage of giant cell arteritis-related anterior ischemic optic neuropathy; patients without this central bright spot sign always had a nonarteritic pathophysiology and therefore did not require emergency corticosteroid

  8. Identification of Potential Mediators of Retinotopic Mapping: A Comparative Proteomic Analysis of Optic Nerve from WT and Phr1 Retinal Knockout Mice

    PubMed Central

    Lee, Andrew R.; Lamb, Rachel R.; Chang, Julietta H.; Erdmann-Gilmore, Petra; Lichti, Cheryl F.; Rohrs, Henry W.; Malone, James P.; Wairkar, Yogesh P.; DiAntonio, Aaron; Townsend, R. Reid; Culican, Susan M.

    2012-01-01

    Retinal ganglion cells (RGCs) transmit visual information topographically from the eye to the brain, creating a map of visual space in retino-recipient nuclei (retinotopy). This process is affected by retinal activity and by activity-independent molecular cues. Phr1, which encodes a presumed E3 ubiquitin ligase (PHR1), is required presynaptically for proper placement of RGC axons in the lateral geniculate nucleus and the superior colliculus, suggesting that increased levels of PHR1 target proteins may be instructive for retinotopic mapping of retinofugal projections. To identify potential target proteins, we conducted a proteomic analysis of optic nerve to identify differentially abundant proteins in the presence or absence of Phr1 in RGCs. 1D gel electrophoresis identified a specific band in controls that was absent in mutants. Targeted proteomic analysis of this band demonstrated the presence of PHR1. Additionally, we conducted an unbiased proteomic analysis that identified 30 proteins as being significantly different between the two genotypes. One of these, heterogeneous nuclear ribonucleoprotein M (hnRNP-M), regulates antero-posterior patterning in invertebrates and can function as a cell surface adhesion receptor in vertebrates. Thus we have demonstrated that network analysis of quantitative proteomic data is a useful approach for hypothesis generation and for identifying biologically relevant targets in genetically altered biological models. PMID:22985349

  9. The microscopic (optical and SEM) examination of dental calculus deposits (DCD). Potential interest in forensic anthropology of a bio-archaeological method.

    PubMed

    Charlier, Philippe; Huynh-Charlier, Isabelle; Munoz, Olivia; Billard, Michel; Brun, Luc; de la Grandmaison, Geoffroy Lorin

    2010-07-01

    This article describes the potential interest in forensic anthropology of the microscopic analysis of dental calculus deposits (DCD), a calcified residue frequently found on the surface of teeth. Its sampling and analysis seem straightforward and relatively reproducible. Samples came from archaeological material (KHB-1 Ra's al-Khabbah and RH-5 Ra's al-Hamra, two Prehistoric graveyards located in the Sultanate of Oman, dated between the 5th and 4th millennium B.C.; Montenzio Vecchia, an Etruscan-Celtic necropolis from the north of Italy, dated between the 5th and 3rd century B.C.; body rests of Agnès Sorel, French royal mistress died in 1450 A.D.; skeleton of Pierre Hazard, French royal notary from the 15th century A.D.). Samples were studies by direct optical microscope (OM) or scanning electron microscopy (SEM). Many cytological, histological and elemental analyses were possible, producing precious data for the identification of these remains, the reconstitution of their alimentation and occupational habits, and propositions for manner of death. Copyright 2010 Elsevier Ireland Ltd. All rights reserved.

  10. Application of a folding-model optical potential to analyzing inelastic pion–nucleus scattering and the in-medium effect on a pion–nucleon amplitude

    SciTech Connect

    Lukyanov, V. K. Zemlyanaya, E. V.; Lukyanov, K. V.; Abdul-Magead, I. A. M.

    2016-11-15

    The folding-model optical potential is generalized in such a way as to apply it to calculating the cross sections for inelastic scattering of π{sup ±}-mesons on {sup 28}Si, {sup 40}Ca, {sup 58}Ni, and {sup 208}Pb nuclei at the energies of 162, 180, 226, and 291 MeV leading to the excitation of the 2{sup +} and 3{sup −} collective states. In doing this, use is made of known nucleon-density distributions in nuclei and the pion–nucleon scattering amplitude whose parameters were obtained previously by fitting the elastic scattering cross sections for the same nuclei. Thus, the values of quadrupole (β{sub 2}) and octupole (β{sub 3}) deformations of nuclei appear here as the only adjustable parameters. The scattering cross section is calculated by solving the relativistic wave equation, whereby effects of relativization and distortion in the entrance and exit scattering channels are taken exactly into account. The cross sections calculated in this way for inelastic scattering are in good agreement with respective experimental data. The importance of the inclusion of in-medium effects in choosing parameters of the pion–nucleon amplitude is emphasized.

  11. Potential-well depth at amorphous-LaAlO{sub 3}/crystalline-SrTiO{sub 3} interfaces measured by optical second harmonic generation

    SciTech Connect

    De Luca, Gabriele; Rubano, Andrea; Gennaro, Emiliano di; Khare, Amit; Granozio, Fabio Miletto; Uccio, Umberto Scotti di; Marrucci, Lorenzo; Paparo, Domenico

    2014-06-30

    By a combination of optical second harmonic generation and transport measurements, we have investigated interfaces formed by either crystalline or amorphous thin films of LaAlO{sub 3} grown on TiO{sub 2}-terminated SrTiO{sub 3}(001) substrates. Our approach aims at disentangling the relative role of intrinsic and extrinsic doping mechanisms in the formation of the two-dimensional electron gas. The different nature of the two mechanisms is revealed when comparing the sample response variation as a function of temperature during annealing in air. However, before the thermal treatment, the two types of interfaces show almost the same intensity of the second harmonic signal, provided the overlayer thickness is the same. As we will show, the second harmonic signal is proportional to the depth of the potential well confining the charges at the interface. Therefore, our result demonstrates that this depth is about the same for the two different material systems. This conclusion supports the idea that the electronic properties of the two-dimensional electron gas are almost independent of the doping mechanism of the quantum well.

  12. Application of a folding-model optical potential to analyzing inelastic pion-nucleus scattering and the in-medium effect on a pion-nucleon amplitude

    NASA Astrophysics Data System (ADS)

    Lukyanov, V. K.; Zemlyanaya, E. V.; Lukyanov, K. V.; Abdul-Magead, I. A. M.

    2016-11-01

    The folding-model optical potential is generalized in such a way as to apply it to calculating the cross sections for inelastic scattering of π ±-mesons on 28Si, 40Ca, 58Ni, and 208Pb nuclei at the energies of 162, 180, 226, and 291 MeV leading to the excitation of the 2+ and 3- collective states. In doing this, use is made of known nucleon-density distributions in nuclei and the pion-nucleon scattering amplitude whose parameters were obtained previously by fitting the elastic scattering cross sections for the same nuclei. Thus, the values of quadrupole ( β 2) and octupole ( β 3) deformations of nuclei appear here as the only adjustable parameters. The scattering cross section is calculated by solving the relativistic wave equation, whereby effects of relativization and distortion in the entrance and exit scattering channels are taken exactly into account. The cross sections calculated in this way for inelastic scattering are in good agreement with respective experimental data. The importance of the inclusion of in-medium effects in choosing parameters of the pion-nucleon amplitude is emphasized.

  13. Growth, Properties, and Theoretical Analysis of M2LiVO4 (M = Rb, Cs) Crystals: Two Potential Mid-Infrared Nonlinear Optical Materials.

    PubMed

    Han, Guopeng; Wang, Ying; Su, Xin; Yang, Zhihua; Pan, Shilie

    2017-05-15

    Mid-Infrared nonlinear optical (Mid-IR NLO) crystals with excellent performances play a particularly important role for applications in areas such as telecommunications, laser guidance, and explosives detection. However, the design and growth of high performance Mid-IR NLO crystals with large NLO efficiency and high laser-damage threshold (LDT) still face numerous fundamental challenge. In this study, two potential Mid-IR NLO materials, Rb2LiVO4 (RLVO) and Cs2LiVO4 (CLVO) with noncentrosymmetric structures (Orthorhombic, Cmc21) were synthesized by high-temperature solution method. Thermal analysis and powder X-ray diffraction demonstrate that RLVO and CLVO melt congruently. Centimeter sized crystals of CLVO have been grown by the top-seeded solution growth method. RLVO and CLVO exhibit strong second harmonic generation (SHG) effects (about 4 and 5 times that of KH2PO4, respectively) with a phase-matching behavior at 1.064 μm, and a wide transparency range (0.33-6.0 μm for CLVO). More importantly, RLVO and CLVO possess a high LDT value (~28 × AgGaS2). In addition, the density functional theory (DFT) and dipole moments studies indicate that the VO4 anionic groups have a dominant contribution to the SHG effects in RLVO and CLVO. These results suggest that the title compounds are promising NLO candidate crystals applied in the Mid-IR region.

  14. Potential use of the topical niacin skin test in early psychosis -- a combined approach using optical reflection spectroscopy and a descriptive rating scale.

    PubMed

    Smesny, Stefan; Berger, Gregor; Rosburg, Timm; Riemann, Sven; Riehemann, Stefan; McGorry, Patrick; Sauer, Heinrich

    2003-01-01

    The niacin skin phenomenon reflects a prostaglandin (PG) mediated flush and oedema reaction. As PG metabolism is linked to breakdown of membrane lipids, diminished sensitivity to niacin application suggests potential disturbance in membrane phospholipid-arachidonic acid-PG pathways. We aimed to evaluate and quantify topical niacin skin reaction in early psychosis using optical reflection spectroscopy (ORS) and a new descriptive assessment scale integrating time course, redness, and oedema. Niacin skin tests were performed on 25 medicated first-episode psychosis patients fulfilling DSM-IV criteria for schizophreniform psychosis or schizophrenia and on 25 healthy controls. Nicotinic acid was applied in four dilution steps to the subjects inner forearm skin and skin reaction was consecutively assessed using ORS and a seven point rating scale. Both descriptive ratings and spectroscopic measures revealed significant group differences at the lower niacin concentrations (0.001 and 0.0001 M). At higher concentrations (0.01 and 0.1 M) only descriptive ratings were capable to show significant group effects. Data of both methods showed moderate to strong correlation (r=0.605) as long as the erythema was not affected by the oedema. The data suggest that niacin sensitivity is inversely correlated with negative symptoms. Both methods demonstrate that niacin sensitivity is impaired in a group of first episode psychosis patients and are therefore able to distinguish a subgroup of patients with metabolic impairment. Niacin sensitivity in high risk populations and the specificity of impaired skin response are subjects of further investigation.

  15. Optical spectroscopy of Dy3+-doped CaGdAlO4 single crystal for potential use in solid-state yellow lasers

    NASA Astrophysics Data System (ADS)

    Xu, Xiaodong; Hu, Zongwen; Li, Ruijuan; Li, Dongzhen; Di, Juqing; Su, Liangbi; Yang, Qiuhong; Sai, Qinglin; Tang, Huili; Wang, Qingguo; Strzęp, Adam; Xu, Jun

    2017-04-01

    The crystal growth, optical spectra and lifetime of Dy:CaGdAlO4 crystal were investigated for the first time to our best knowledge. Single Dy:CaGdAlO4 crystal with size of Φ4 × 40 mm3 was grown by floating zone method. The peak absorption cross-sections were calculated to be 2.43 × 10-21cm2 and 1.28 × 10-21 cm2 at 453 nm for σ and π polarizations. The Judd-Ofelt (JO) parameters of Ω2, Ω4 and Ω6 were calculated to be 1.8 × 10-20cm2, 1.0 × 10-20cm2 and 0.5 × 10-20cm2, respectively. The emission cross-sections were calculated to be 0.51 × 10-20cm2 and 0.55 × 10-20cm2 for σ and π polarizations. The fluorescence decay time is 222 μs. The results indicate that the Dy:CaGdAlO4 crystal is a potential candidate for yellow laser operation.

  16. White and Gray Matter Volume Changes and Correlation with Visual Evoked Potential in Patients with Optic Neuritis: A Voxel-Based Morphometry Study.

    PubMed

    Huang, Xin; Zhang, Qiang; Hu, Pei-Hong; Zhong, Yu-Lin; Zhang, Ying; Wei, Rong; Xu, Ting-Ting; Shao, Yi

    2016-04-05

    The aim of this study was to investigate potential morphological alterations of gray and white matter in patients with optic neuritis (ON) and their relationship with behavioral performance, using voxel-based morphometry (VBM). Twelve (4 males, 8 females) patients with ON and 12 (4 males, 8 females) age-, sex-, and education-matched healthy controls (HCs) underwent magnetic resonance imaging (MRI). Imaging data were analyzed using two-sample t tests to identify group differences in gray and white matter volume (GMV, WMV). Correlation analysis was used to explore relationships between observed GMV and WMV of different areas and visual evoked potential (VEP) in ON. Compared with HCs, ON patients had: significantly decreased GMV in the left postcentral gyrus, left inferior frontal gyrus, left anterior cingulate, left and right middle frontal gyrus, and right inferior parietal lobule; decreased WMV in the left middle frontal gyrus, right superior frontal gyrus, left precentral gyrus and right inferior parietal lobule; and increased WMV in the left fusiform gyrus and left inferior parietal lobule. VEP latency of the right eye in ON correlated positively with WMV signal value of the left fusiform gyrus (r=0.726, p=0.008), and negatively with GMV signal value of the right inferior parietal lobule (r=-0.611, p=0.035). Duration of ON correlated negatively with WMV signal value of the right superior frontal gyrus (r=-0.662, p=0.019), while best-corrected visual acuity (VA) of the right eye correlated negatively with WMV signal value of the left middle frontal gyrus (r=-0.704, p=0.011). These results suggest significant brain involvement in ON, which may reflect the underlying pathologic mechanism. Correlational results demonstrate that VEP in ON is closely associated with WMV and GMV atrophy in many brain regions.

  17. White and Gray Matter Volume Changes and Correlation with Visual Evoked Potential in Patients with Optic Neuritis: A Voxel-Based Morphometry Study

    PubMed Central

    Huang, Xin; Zhang, Qiang; Hu, Pei-Hong; Zhong, Yu-Lin; Zhang, Ying; Wei, Rong; Xu, Ting-Ting; Shao, Yi

    2016-01-01

    Background The aim of this study was to investigate potential morphological alterations of gray and white matter in patients with optic neuritis (ON) and their relationship with behavioral performance, using voxel-based morphometry (VBM). Material/Methods Twelve (4 males, 8 females) patients with ON and 12 (4 males, 8 females) age-, sex-, and education-matched healthy controls (HCs) underwent magnetic resonance imaging (MRI). Imaging data were analyzed using two-sample t tests to identify group differences in gray and white matter volume (GMV, WMV). Correlation analysis was used to explore relationships between observed GMV and WMV of different areas and visual evoked potential (VEP) in ON. Results Compared with HCs, ON patients had: significantly decreased GMV in the left postcentral gyrus, left inferior frontal gyrus, left anterior cingulate, left and right middle frontal gyrus, and right inferior parietal lobule; decreased WMV in the left middle frontal gyrus, right superior frontal gyrus, left precentral gyrus and right inferior parietal lobule; and increased WMV in the left fusiform gyrus and left inferior parietal lobule. VEP latency of the right eye in ON correlated positively with WMV signal value of the left fusiform gyrus (r=0.726, p=0.008), and negatively with GMV signal value of the right inferior parietal lobule (r=−0.611, p=0.035). Duration of ON correlated negatively with WMV signal value of the right superior frontal gyrus (r=−0.662, p=0.019), while best-corrected visual acuity (VA) of the right eye correlated negatively with WMV signal value of the left middle frontal gyrus (r=−0.704, p=0.011). Conclusions These results suggest significant brain involvement in ON, which may reflect the underlying pathologic mechanism. Correlational results demonstrate that VEP in ON is closely associated with WMV and GMV atrophy in many brain regions. PMID:27045330

  18. Potential Nighttime Contamination of CERES Clear-sky Field of View by Optically Thin Cirrus during the CRYSTAL-FACE Campaign

    NASA Technical Reports Server (NTRS)

    Lee, Yong-Keun; Yang, Ping; Hu, Yongxiang; Baum, Bryan A.; Loeb, Norman G.; Gao, Bo-Cai

    2006-01-01

    We investigate the outgoing broadband longwave (LW, 5 to approx. 200 microns) and window (WIN, 8 to approx. 12 microns) channel radiances at the top of atmosphere (TOA) under clear-sky conditions, using data acquired by the Cloud and the Earth s Radiant Energy System (CERES) and Moderate-Resolution Imaging Spectroradiometer (MODIS) instruments onboard the NASA Terra satellite platform. In this study, detailed analyses are performed on the CERES Single Scanner Footprint TOA/Surface Fluxes and Clouds product to understand the radiative effect of thin cirrus. The data are acquired over the Florida area during the Cirrus Regional Study of Tropical Anvils and Cirrus Layers Florida Area Cirrus Experiment (CRYSTAL-FACE) field program. Of particular interest is the anisotropy associated with the radiation field. Measured CERES broadband radiances are compared to those obtained from rigorous radiative transfer simulations. Analysis of results from this comparison indicates that the simulated radiances tend to be larger than their measured counterparts, with differences ranging from 2.1% to 8.3% for the LW band and from 1.7% to 10.6% for the WIN band. The averaged difference in radiance is approximately 4% for both the LW and WIN channels. A potential cause for the differences could be the presence of thin cirrus (i.e., optically thin ice clouds with visible optical thicknesses smaller than approximately 0.3). The detection and quantitative analysis of these thin cirrus clouds are challenging even with sophisticated multispectral instruments. While large differences in radiance between the CERES observations and the theoretical calculations are found, the corresponding difference in the anisotropic factors is very small (0.2%). Furthermore, sensitivity studies show that the influence due to a 1 K bias of the surface temperature on the errors of the LW and WIN channel radiances is of the same order as that associated with a 2% bias of the surface emissivity. The LW and WIN

  19. Early in-flight detection of SO2 via Differential Optical Absorption Spectroscopy: a feasible aviation safety measure to prevent potential encounters with volcanic plumes

    NASA Astrophysics Data System (ADS)

    Vogel, L.; Galle, B.; Kern, C.; Delgado Granados, H.; Conde, V.; Norman, P.; Arellano, S.; Landgren, O.; Lübcke, P.; Alvarez Nieves, J. M.; Cárdenas Gonzáles, L.; Platt, U.

    2011-05-01

    Volcanic ash constitutes a risk to aviation, mainly due to its ability to cause jet engines to fail. Other risks include the possibility of abrasion of windshields and potentially serious damage to avionic systems. These hazards have been widely recognized since the early 1980s, when volcanic ash provoked several incidents of engine failure in commercial aircraft. In addition to volcanic ash, volcanic gases also pose a threat. Prolonged and/or cumulative exposure to sulphur dioxide (SO2) or sulphuric acid (H2SO4) aerosols potentially affects e.g. windows, air frame and may cause permanent damage to engines. SO2 receives most attention among the gas species commonly found in volcanic plumes because its presence above the lower troposphere is a clear proxy for a volcanic cloud and indicates that fine ash could also be present. Up to now, remote sensing of SO2 via Differential Optical Absorption Spectroscopy (DOAS) in the ultraviolet spectral region has been used to measure volcanic clouds from ground based, airborne and satellite platforms. Attention has been given to volcanic emission strength, chemistry inside volcanic clouds and measurement procedures were adapted accordingly. Here we present a set of experimental and model results, highlighting the feasibility of DOAS to be used as an airborne early detection system of SO2 in two spatial dimensions. In order to prove our new concept, simultaneous airborne and ground-based measurements of the plume of Popocatépetl volcano, Mexico, were conducted in April 2010. The plume extended at an altitude around 5250 m above sea level and was approached and traversed at the same altitude with several forward looking DOAS systems aboard an airplane. These DOAS systems measured SO2 in the flight direction and at ± 40 mrad (2.3°) angles relative to it in both, horizontal and vertical directions. The approaches started at up to 25 km distance to the plume and SO2 was measured at all times well above the detection limit. In

  20. Early in-flight detection of SO2 via Differential Optical Absorption Spectroscopy: a feasible aviation safety measure to prevent potential encounters with volcanic plumes

    NASA Astrophysics Data System (ADS)

    Vogel, L.; Galle, B.; Kern, C.; Delgado Granados, H.; Conde, V.; Norman, P.; Arellano, S.; Landgren, O.; Lübcke, P.; Alvarez Nieves, J. M.; Cárdenas Gonzáles, L.; Platt, U.

    2011-09-01

    Volcanic ash constitutes a risk to aviation, mainly due to its ability to cause jet engines to fail. Other risks include the possibility of abrasion of windshields and potentially serious damage to avionic systems. These hazards have been widely recognized since the early 1980s, when volcanic ash provoked several incidents of engine failure in commercial aircraft. In addition to volcanic ash, volcanic gases also pose a threat. Prolonged and/or cumulative exposure to sulphur dioxide (SO2) or sulphuric acid (H2SO4) aerosols potentially affects e.g. windows, air frame and may cause permanent damage to engines. SO2 receives most attention among the gas species commonly found in volcanic plumes because its presence above the lower troposphere is a clear proxy for a volcanic cloud and indicates that fine ash could also be present. Up to now, remote sensing of SO2 via Differential Optical Absorption Spectroscopy (DOAS) in the ultraviolet spectral region has been used to measure volcanic clouds from ground based, airborne and satellite platforms. Attention has been given to volcanic emission strength, chemistry inside volcanic clouds and measurement procedures were adapted accordingly. Here we present a set of experimental and model results, highlighting the feasibility of DOAS to be used as an airborne early detection system of SO2 in two spatial dimensions. In order to prove our new concept, simultaneous airborne and ground-based measurements of the plume of Popocatépetl volcano, Mexico, were conducted in April 2010. The plume extended at an altitude around 5250 m above sea level and was approached and traversed at the same altitude with several forward looking DOAS systems aboard an airplane. These DOAS systems measured SO2 in the flight direction and at ±40 mrad (2.3°) angles relative to it in both, horizontal and vertical directions. The approaches started at up to 25 km distance to the plume and SO2 was measured at all times well above the detection limit. In

  1. Early in-flight detection of SO2 via Differential Optical Absorption Spectroscopy: A feasible aviation safety measure to prevent potential encounters with volcanic plumes

    USGS Publications Warehouse

    Vogel, L.; Galle, B.; Kern, C.; Delgado, Granados H.; Conde, V.; Norman, P.; Arellano, S.; Landgren, O.; Lubcke, P.; Alvarez, Nieves J.M.; Cardenas, Gonzales L.; Platt, U.

    2011-01-01

    Volcanic ash constitutes a risk to aviation, mainly due to its ability to cause jet engines to fail. Other risks include the possibility of abrasion of windshields and potentially serious damage to avionic systems. These hazards have been widely recognized 5 since the early 1980s, when volcanic ash provoked several incidents of engine failure in commercial aircraft. In addition to volcanic ash, volcanic gases also pose a threat. Prolonged and/or cumulative exposure to sulphur dioxide (SO2) or sulphuric acid (H2SO4) aerosols potentially affects e.g. windows, air frame and may cause permanent damage to engines. SO2 receives most attention among the gas species commonly found in 10 volcanic plumes because its presence above the lower troposphere is a clear proxy for a volcanic cloud and indicates that fine ash could also be present. Up to now, remote sensing of SO2 via Differential Optical Absorption Spectroscopy (DOAS) in the ultraviolet spectral region has been used to measure volcanic clouds from ground based, airborne and satellite platforms. Attention has been given to vol- 15 canic emission strength, chemistry inside volcanic clouds and measurement procedures were adapted accordingly. Here we present a set of experimental and model results, highlighting the feasibility of DOAS to be used as an airborne early detection system of SO2 in two spatial dimensions. In order to prove our new concept, simultaneous airborne and ground-based measurements of the plume of Popocatepetl volcano, Mexico, were conducted in April 2010. The plume extended at an altitude around 5250 m above sea level and was approached and traversed at the same altitude with several forward looking DOAS systems aboard an airplane. These DOAS systems measured SO2 in the flight direction and at ±40 mrad (2.3◦) angles relative to it in both, horizontal and vertical directions. The approaches started at up to 25 km distance to 25 the plume and SO2 was measured at all times well above the detection

  2. Optic neuritis

    MedlinePlus

    Retro-bulbar neuritis; Multiple sclerosis - optic neuritis; Optic nerve - optic neuritis ... The exact cause of optic neuritis is unknown. The optic nerve carries visual information from your eye to the brain. The nerve can swell when ...

  3. The use of light-based (optical) detection systems as adjuncts in the detection of oral cancer and oral potentially malignant disorders: a systematic review.

    PubMed

    Rashid, A; Warnakulasuriya, S

    2015-05-01

    In recent decades, optical techniques utilising the principles of chemiluminescence and tissue autofluorescence have emerged to facilitate the early detection of any oral mucosal changes suspicious of cancer. To evaluate the effectiveness of devices that utilise the principles of chemiluminescence and tissue autofluorescence as adjuncts in the detection of oral cancer and oral potentially malignant disorders (OPMDs). A systematic review of the published literature to evaluate the effectiveness of the ViziLite(®) and ViziLite(®) Plus with toluidine blue, MicroLux™/DL and the VELscope™ as aids in the detection of oral cancer and OPMDs. Twenty-five primary studies published between 2004 and 2013 satisfied our criteria for selection - 13 utilised chemiluminescence and 12 tissue autofluorescence. Some had utilised both study methods on the same population. Chemiluminescence shows good sensitivity at detecting any OPMDs and oral cancer. However, it preferentially detects leukoplakia and may fail to spot red patches. The additive use of toluidine blue may improve specificity. Tissue autofluorescence is sensitive at detecting white, red and white and red patches, and the area of fluorescence visualisation loss (FVL) often extends beyond the clinically visible lesion. However, in addition to OPMDs, VELScope may detect erythematous lesions of benign inflammation resulting in false-positive test results. There is limited evidence for their use in primary care, and these tools are better suited to specialist clinics in which there is a higher prevalence of disease and where experienced clinicians may better discriminate between benign and malignant lesions. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  4. Nonlinear Optics and Applications

    NASA Technical Reports Server (NTRS)

    Abdeldayem, Hossin A. (Editor); Frazier, Donald O. (Editor)

    2007-01-01

    Nonlinear optics is the result of laser beam interaction with materials and started with the advent of lasers in the early 1960s. The field is growing daily and plays a major role in emerging photonic technology. Nonlinear optics play a major role in many of the optical applications such as optical signal processing, optical computers, ultrafast switches, ultra-short pulsed lasers, sensors, laser amplifiers, and many others. This special review volume on Nonlinear Optics and Applications is intended for those who want to be aware of the most recent technology. This book presents a survey of the recent advances of nonlinear optical applications. Emphasis will be on novel devices and materials, switching technology, optical computing, and important experimental results. Recent developments in topics which are of historical interest to researchers, and in the same time of potential use in the fields of all-optical communication and computing technologies, are also included. Additionally, a few new related topics which might provoke discussion are presented. The book includes chapters on nonlinear optics and applications; the nonlinear Schrodinger and associated equations that model spatio-temporal propagation; the supercontinuum light source; wideband ultrashort pulse fiber laser sources; lattice fabrication as well as their linear and nonlinear light guiding properties; the second-order EO effect (Pockels), the third-order (Kerr) and thermo-optical effects in optical waveguides and their applications in optical communication; and, the effect of magnetic field and its role in nonlinear optics, among other chapters.

  5. EDITORIAL: Transformation optics Transformation optics

    NASA Astrophysics Data System (ADS)

    Shalaev, Vladimir M.; Pendry, John

    2011-02-01

    possibly even DNA molecules. Light-concentrating devices, such as the optical black hole, can be used for efficient solar light collection in photovoltaic elements for renewable energy. With the dramatic advances in micro- and nanofabrication methods, we are presented with the opportunity to control light in a way that was not possible with the materials provided to us by nature. In an artificial pattern of sub-wavelength elements, the propagation of electromagnetic energy can be defined by an equivalent spatial and spectral dispersion of effective dielectric and magnetic properties. These synthetic structures, which can be fabricated with a desired spatial distribution of effective permittivity epsilon(r) and permeability μ(r), offer a unique potential to guide and control the flow of electromagnetic energy in such an engineered optical space. No longer are we constrained by the electromagnetic response of natural materials and their chemical compounds. Instead, we can tailor the shape and size of the structural units of the metamaterials, or tune their composition and morphology to provide new functionality.

  6. Optical gyroscope

    NASA Technical Reports Server (NTRS)

    Goldstein, R. M.; Goss, W. C.

    1978-01-01

    Instrument uses phase difference between two beams of light to measure rotation. It is considerably simpler and more reliable than conventional spinning-mass gyroscopes used for inertial guidance and is more compact, lighter, and potentially less expensive. Moreover, optical gyroscope requires no warmup period. Although conceived for spacecraft and satellite stabilization, gyroscope should also find applications in flight instruments for private, commercial, and military aircraft.

  7. Rayleigh-based distributed temperature sensing and fiber Bragg grating point temperature sensing with a single optical fiber on high electrical potential of 1 MV

    NASA Astrophysics Data System (ADS)

    Ringel, T.; Willsch, M.; Bosselmann, T.

    2017-04-01

    A temperature measurement of a high voltage bushing (HV-Bushing) is presented. An optical fiber with several inscribed Fiber Bragg Gratings (FBGs) was used to measure the temperature at given positions and a Rayleigh-based measurement technique was used to measure the temperature (profile) between the FBGs. The used optical frequencies for the FBG and Rayleigh measurement had to be separated to achieve good results. Voltages of up to 1 MV were applied to the HV-Bushing during the measurement.

  8. Optical Interconnect

    NASA Astrophysics Data System (ADS)

    Gaburro, Zeno

    The progress of silicon electronic industry is based on scaling down the minimum feature size of integrated circuits. Speed, density and costs of devices improve with scaling, but unfortunately the performance of interconnect worsens, both in terms of speed and power consumption. This issue -- the ``interconnect bottleneck'' -- is envisioned as a critical showstopper of electronic industry in the near future. The physical reason behind the interconnect bottleneck is the resistive nature of metals. The introduction of copper in place of aluminum has temporarily improved the interconnect performance, but on the other hand in a few years a more disruptive solution will be required in order to keep the current pace of progress. Optical interconnect is an intriguing alternative to metallic wires, because light can travel in dielectrics, and even in vacuum. At present, optical technology in silicon is not mature for industrial implementation. For this very same reason, however, it is also rich of research opportunities with large potential payoff. The rationale of this chapter has been to trace a snapshot of the current interconnect limitations; to point out the basic differences between the electrical and optical interconnect from different perspectives, ranging from basic physics up to system layouts; and to give a flavor of suggested practical realization of optical solutions. Any of these goals would be too ambitious for a book chapter without a hopefully rich and up-to-date bibliography.

  9. Advanced Adaptive Optics Control Techniques

    DTIC Science & Technology

    1979-01-01

    Optimal estimation and control methods for high energy laser adaptive optics systems are described. Three system types are examined: Active...the adaptive optics approaches and potential system implementations are recommended.

  10. Deformable Nanolaminate Optics

    SciTech Connect

    Olivier, S S; Papavasiliou, A P; Barbee, T W; Miles, R R; Walton, C C; Cohn, M B; Chang, K

    2006-05-12

    We are developing a new class of deformable optic based on electrostatic actuation of nanolaminate foils. These foils are engineered at the atomic level to provide optimal opto-mechanical properties, including surface quality, strength and stiffness, for a wide range of deformable optics. We are combining these foils, developed at Lawrence Livermore National Laboratory (LLNL), with commercial metal processing techniques to produce prototype deformable optics with aperture sizes up to 10 cm and actuator spacing from 1 mm to 1 cm and with a range of surface deformation designed to be as much as 10 microns. The existing capability for producing nanolaminate foils at LLNL, coupled with the commercial metal processing techniques being used, enable the potential production of these deformable optics with aperture sizes of over 1 m, and much larger deformable optics could potentially be produced by tiling multiple deformable segments. In addition, based on the fabrication processes being used, deformable nanolaminate optics could potentially be produced with areal densities of less than 1 kg per square m for applications in which lightweight deformable optics are desirable, and deformable nanolaminate optics could potentially be fabricated with intrinsically curved surfaces, including aspheric shapes. We will describe the basic principles of these devices, and we will present details of the design, fabrication and characterization of the prototype deformable nanolaminate optics that have been developed to date. We will also discuss the possibilities for future work on scaling these devices to larger sizes and developing both devices with lower areal densities and devices with curved surfaces.

  11. Ex vivo investigations on the potential of optical coherence tomography (OCT) as a diagnostic tool for reproductive medicine in a bovine model.

    PubMed

    Trottmann, Matthias; Kölle, Sabine; Leeb, Regina; Doering, Daniel; Reese, Sven; Stief, Christian G; Dulohery, Kate; Leavy, Myles; Kuznetsova, Julia; Homann, Christian; Sroka, Ronald

    2016-01-01

    Routine infertility investigations in the male and female include imaging techniques such as ultrasonography and endoscopy (fertiloscopy). However, these techniques lack the resolution to localize vital sperm or to reveal detailed morphological analysis of the oviduct which is often the cause of infertility in females. Therefore we set out to evaluate the efficiency of optical coherence tomography (OCT) as a diagnostic imaging tool for micron-scale visualization of the male and female genital tract. Using the bovine as a model, the optical features of the Telesto(TM) , Ganymede(TM) (both Thorlabs) and Niris(TM) (Imalux) OCT imaging systems were compared.

  12. Optical Circuitry Cooperative

    NASA Astrophysics Data System (ADS)

    Gibbs, H. M.; Gibson, U.; Peyghambarian, N.; Sarid, D.; Stegeman, G.

    1985-01-01

    An Optical Circuitry Cooperative (OCC) has been formed as an NSF cooperative research center in which six or more companies contribute financial support; NSF provides support which declines to zero in five years. Companies benefit from a center by early access to research results, leverage for their research dollars, participation in research selection, and improved relations with faculty and students. The university receives support for a major research program that increases its research capability, provides reasonably stable funding, and opens more opportunities for graduate students. The potential of optical circuitry has been discussed for many years, but the excitement is growing rapidly on the strength of the success of optical fibers for optical transmission, the generation of subpicosecond opitcal pulses, and the development of promising optical logic elements, such as optical bistable devices. And yet, much research remains to be done to discover the best nonlinear optical materials and fabrication techniques. OCC will perform research to provide a data base to allow the development of optical circuitry devices. The areas encompassed by OCC include all-optical logic, picosecond decision-making, guided-wave preprocessors, opti-cal interconnects within computers (both fiber and whole-array imaging), optical storage, and optical computer architecture and devices.

  13. Bio-optical profiling floats as new observational tools for biogeochemical and ecosystem studies: Potential synergies with ocean color remote sensing

    SciTech Connect

    Claustre, H.; Bishop, J.; Boss, E.; Bernard, S.; Berthon, J.-F.; Coatanoan, C.; Johnson, K.; Lotiker, A.; Ulloa, O.; Perry, M.J.; D'Ortenzio, F.; D'andon, O.H.F.; Uitz, J.

    2009-10-01

    Profiling floats now represent a mature technology. In parallel with their emergence, the field of miniature, low power bio-optical and biogeochemical sensors is rapidly evolving. Over recent years, the bio-geochemical and bio-optical community has begun to benefit from the increase in observational capacities by developing profiling floats that allow the measurement of key biooptical variables and subsequent products of biogeochemical and ecosystem relevance like Chlorophyll a (Chla), optical backscattering or attenuation coefficients which are proxies of Particulate Organic Carbon (POC), Colored Dissolved Organic Matter (CDOM). Thanks to recent algorithmic improvements, new bio-optical variables such as backscattering coefficient or absorption by CDOM, at present can also be extracted from space observations of ocean color. In the future, an intensification of in situ measurements by bio-optical profiling floats would permit the elaboration of unique 3D/4D bio-optical climatologies, linking surface (remotely detected) properties to their vertical distribution (measured by autonomous platforms), with which key questions in the role of the ocean in climate could be addressed. In this context, the objective of the IOCCG (International Ocean Color Coordinating Group) BIO-Argo working group is to elaborate recommendations in view of a future use of bio-optical profiling floats as part of a network that would include a global array that could be 'Argo-relevant', and specific arrays that would have more focused objectives or regional targets. The overall network, realizing true multi-scale sustained observations of global marine biogeochemistry and biooptics, should satisfy the requirements for validation of ocean color remote sensing as well as the needs of a wider community investigating the impact of global change on biogeochemical cycles and ecosystems. Regarding the global profiling float array, the recommendation is that Chla as well as POC should be the key

  14. [Progress in optical imaging].

    PubMed

    Bremer, C; Ntziachristos, V; Mahmood, U; Tung, C H; Weissleder, R

    2001-02-01

    Different optical imaging technologies have significantly progressed over the last years. Besides advances in imaging techniques and image reconstruction, new "smart" optical contrast agents have been developed which can be used to detect molecular targets (such as endogenous enzymes) in vivo. The combination of novel imaging technologies coupled with smart agents bears great diagnostic potential both clinically and experimentally. This overview outlines the basic principles of optical imaging and summarizes the current state of the art.

  15. Beam optics test stand

    NASA Astrophysics Data System (ADS)

    Humphries, S., Jr.; Hess, G.

    1988-04-01

    The design and construction of the Beam Optics Test Stand (BOTS) is presented. A variety of computer compatible diagnostics has been developed to facilitate experiments. Extensive theoretical work is presented leading to the identification of two potential methods to correct aberrations in magnetic optics: biased grid arrays and space charge corrected solenoidal lenses. A series of experiments is presented which demonstrates, for the first time, the feasibility of space charge corrected optics.

  16. Optical Thermal Ratchet

    NASA Astrophysics Data System (ADS)

    Faucheux, L. P.; Bourdieu, L. S.; Kaplan, P. D.; Libchaber, A. J.

    1995-02-01

    We present an optical realization of a thermal ratchet. Directed motion of Brownian particles in water is induced by modulating in time a spatially periodic but asymmetric optical potential. The net drift shows a maximum as a function of the modulation period. The experimental results agree with a simple theoretical model based on diffusion.

  17. Nonlinear optical materials.

    PubMed

    Eaton, D F

    1991-07-19

    The current state of materials development in nonlinear optics is summarized, and the promise of these materials is critically evaluated. Properties and important materials constants of current commercial materials and of new, promising, inorganic and organic molecular and polymeric materials with potential in second- and third-order nonlinear optical applications are presented.

  18. Potential antifertility agents. 6. Synthesis and biological activities of optical isomers of 4 beta-(p-methozyphenyl)-2 beta-methylcyclohexane-alpha-carboxylic acid and related compounds.

    PubMed

    Crenshaw, R R; Jenks, T A; Luke, G M; Bialy, G

    1974-12-01

    The optical isomers of the title compound were synthesized and the biological potencies of the two enantiomers were compared. There was essentially no difference in their hypocholesterolemic activities, as had been predicted, and little or no difference between their uterotropic potencies. The approximately equal uterotropic activities seen with the enantiomers is explained in terms of stereochemical requirements at the receptor level for an estrogenic response. A working model of an estrogenic receptor is proposed. An accompanying paper provides support for the proposed model.

  19. Alzheimer's disease: A review of its visual system neuropathology. Optical coherence tomography-a potential role as a study tool in vivo.

    PubMed

    Cunha, J P; Moura-Coelho, N; Proença, R P; Dias-Santos, A; Ferreira, J; Louro, C; Castanheira-Dinis, A

    2016-11-01

    Alzheimer's disease (AD) is a prevalent, long-term progressive degenerative disorder with great social impact. It is currently thought that, in addition to neurodegeneration, vascular changes also play a role in the pathophysiology of the disease. Visual symptoms are frequent and are an early clinical manifestation; a number of psychophysiologic changes occur in visual function, including visual field defects, abnormal contrast sensitivity, abnormalities in color vision, depth perception deficits, and motion detection abnormalities. These visual changes were initially believed to be solely due to neurodegeneration in the posterior visual pathway. However, evidence from pathology studies in both animal models of AD and humans has demonstrated that neurodegeneration also takes place in the anterior visual pathway, with involvement of the retinal ganglion cells' (RGCs) dendrites, somata, and axons in the optic nerve. These studies additionally showed that patients with AD have changes in retinal and choroidal microvasculature. Pathology findings have been corroborated in in-vivo assessment of the retina and optic nerve head (ONH), as well as the retinal and choroidal vasculature. Optical coherence tomography (OCT) in particular has shown great utility in the assessment of these changes, and it may become a useful tool for early detection and monitoring disease progression in AD. The authors make a review of the current understanding of retinal and choroidal pathological changes in patients with AD, with particular focus on in-vivo evidence of retinal and choroidal neurodegenerative and microvascular changes using OCT technology.

  20. Optical processing

    NASA Astrophysics Data System (ADS)

    Gustafson, S. C.

    1985-12-01

    The technical contributions were as follows: (1) Optical parallel 2-D neighborhood processor and optical processor assessment technique; (2) High accuracy with moderately accurate components and optical fredkin gate architectures; (3) Integrated optical threshold computing, pipelined polynomial processor, and all optical analog/digital converter; (4) Adaptive optical associative memory model with attention; (5) Effectiveness of parallelism and connectivity in optical computers; (6) Optical systolic array processing using an integrated acoustooptic module; (7) Optical threshold elements and networks, holographic threshold processors, adaptive matched spatial filtering, and coherence theory in optical computing; (8) Time-varying optical processing for sub-pixel targets, optical Kalman filtering, and adaptive matched filtering; (9) Optical degrees of freedom, ultra short optical pulses, number representations, content-addressable-memory processors, and integrated optical Givens rotation devices; (10) Optical J-K flip flop analysis and interfacing for optical computers; (11) Matrix multiplication algorithms and limits of incoherent optical computers; (12) Architecture for machine vision with sensor fusion, pattern recognition functions, and neural net implementations; (13) Optical computing algorithms, architectures, and components; and (14) Dynamic optical interconnections, advantages and architectures.

  1. MO-G-BRF-07: Optical Characterization of Novel Terbium-Doped Nanophosphors Excited by Clinical Electron and Photon Beams for Potential Use in Molecular Imaging Or Photodynamic Therapy

    SciTech Connect

    Darafsheh, A; Paik, T; Tenuto, M; Najmr, S; Friedberg, J; Murray, C; Finlay, J

    2014-06-15

    Purpose: Optical properties of terbium (Tb3+)-doped gadolinium trifluoride (GdF3) nanoplates irradiated by electron and photon beams were investigated for their potential as optical probes. The contribution of induced Cerenkov radiation in exciting the nanophosphors was investigated as well. Methods: The emission spectra of Terbium-doped GdF3 dispersed in hexane, embedded in tissue mimicking phantoms were collected by an optical fiber connected to a CCD-coupled spectrograph, while the samples were irradiated by a medical linear accelerator with electron beams of energies 6, 9, 12, 16, and 20 MeV or X-ray beams of energies of 6, and 15 MV. The contribution of induced Cerenkov radiation in exciting the nanophosphores was investigated in a dedicated experimental apparatus through optical isolation of the samples and also by using 125 kVp X-ray beams whose energy is below the threshold for generating Cerenkov radiation in that medium. Results: Terbium-doped GdF3 nanoplates show characteristic cathodoluminescence emission peaks at 488, 543, 586, and 619 nm, which are responsible for the characteristic f-f transition of terbium ion. In a series of experiments, the contribution of Cerenkov radiation in the luminescence of such nanophosphors was ruled out. Conclusion: We have characterized the optical properties of Terbium-doped GdF3 nanoplates. Such nanocrystals with emission tunability and high surface area that facilitates attachment with targeting reagents are promising in situ light source candidates for molecular imaging or exciting a photosensitizer for ultralow fluence photodynamic therapy. This work is supported by the Department of Radiation Oncology at the University of Pennsylvania, the American Cancer Society through IRG-78-002-28, and the University of Pennsylvania's Nano/Bio Interface Center through NSEC DMR08-32802.

  2. An optical heterodyne densitometer

    NASA Technical Reports Server (NTRS)

    Migdall, A. L.; Zheng, Ying Cong; Hardis, J.; Snyder, J. J.

    1988-01-01

    Researchers are developing an optical heterodyne densitometer with the potential to measure optical density over an unprecedented dynamic range with high accuracy and sensitivity. This device uses a Mach-Zender interferometer configuration with heterodyne detection to make direct comparisons between optical and RF attenuators. Researchers expect to attain measurements of filter transmittance down to 10 to the minus 12th power with better than 1 percent uncertainty. In addition, they intend to extend the technique to the problem of measuring low levels of light scattering from reflective and transmissive optics.

  3. Optical Computing and Nonlinear Optical Signal Processing

    NASA Astrophysics Data System (ADS)

    Peyghambarian, N.

    1987-01-01

    Employment of optical techniques in signal processing and communication and computing systems has become a major research and development effort at many industrial, government, and university laboratories across the nation and in Europe and Japan. implementation of optical computing concepts and the use of bistable etalons and non-linear logic devices in computing have gained a lot of support and enthusiasm from the optics community in recent years. The significance Iof this field and its potential importance in future technologies is evidenced by the large number of conferences, workshops, and special issues on the subject.

  4. Holographic optics

    SciTech Connect

    Cindrich, I

    1988-01-01

    These proceeding collect paper on holographic optics. Topics include: holographic helmet displays; optical performance of holographic kinoforms; lR, visible, UV and XUV Bragg holograms; diffractive optics; holographic laser-protective eyewear; interferometry; and hologon deflectors.

  5. Optical subcarrier multiplexing for multigigabit optical communication

    NASA Astrophysics Data System (ADS)

    Donkor, Eric

    1998-07-01

    Future broadband fiber communication networks for commercial and/or military application will require tens to hundreds of communication channels, each channel transporting multigigabit data resulting in an aggregate throughput upwards of 100 Gb/s. Optical-based systems have the potential for realizing such networks because of the inherent speed of optical signals, and the large optical (30-terahertz) bandwidth that can be exploited for communication. Optical signal multiplexing in the spectral and temporal domains provides means of interconnecting and transporting large user data through a network. One approach to achieving multigigabit data transport via time division multiplexed requires the development of femtosecond mode-locked lasers or soliton lasers of high repetition rates. Such lasers are bulky making them impractical for systems applications. Furthermore their performance can be severely affected by optical nonlinearities. WDM offers another approach to multigigabit data transport. Typically WDM systems utilize a separate single frequency laser for each channel. Stabilizing and controlling each individual wavelength of a high density WDM system is difficult and costly. Furthermore cross-talk and cross-phase modulation limit the channel capacity in WDM systems. In this paper we propose a subcarrier multiplexing scheme as an alternative to multigigabit fiber optics data communication. In this approach, a comb of optical RF subcarriers are generated in a matched-pair of optical traveling-wave amplifiers (TWA). Each subcarrier serves as a transmission channel. The most important aspect of this approach is that optical processing of the subcarriers are done via the main optical carrier. Thus amplification of the main carrier translates into a direct amplification of the subcarriers. We present theoretical framework and simulation results for optical RF subcarrier generation.

  6. Nonlinear optics

    SciTech Connect

    Boyd, R.W. . Inst. of Optics)

    1992-01-01

    Nonlinear optics is the study of the interaction of intense laser light with matter. This book is a textbook on nonlinear optics at the level of a beginning graduate student. The intent of the book is to provide an introduction to the field of nonlinear optics that stresses fundamental concepts and that enables the student to go on to perform independent research in this field. This book covers the areas of nonlinear optics, quantum optics, quantum electronics, laser physics, electrooptics, and modern optics.

  7. Disparities between Phaeocystis in situ and optically-derived carbon biomass and growth rates: potential effect on remote-sensing primary production estimates

    NASA Astrophysics Data System (ADS)

    Peperzak, L.; van der Woerd, H. J.; Timmermans, K. R.

    2014-04-01

    The oceans play a pivotal role in the global carbon cycle. Unfortunately, the daily production of organic carbon, the product of phytoplankton standing stock and growth rate cannot be measured globally by discrete oceanographic methods. Instead, optical proxies from Earth-orbiting satellites must be used. To test the accuracy of optically-derived proxies of phytoplankton physiology and growth rate, standard ex situ data from the wax and wane of a Phaeocystis bloom in laboratory mesocosms were compared with hyperspectral reflectance data. Chlorophyll biomass could be estimated accurately from reflectance using specific chlorophyll absorption algorithms. However, the conversion of chlorophyll (Chl) to carbon (C) was obscured by the observed increase in C : Chl under nutrient-limited growth. C : Chl was inversely correlated (r2 = 0.88) with Photosystem II quantum efficiency (Fv/Fm), the in situ fluorometric oceanographic proxy for growth rate. In addition, the optical proxy for growth rate, the quantum efficiency of fluorescence ϕ was linearly correlated to Fv/Fm (r2 = 0.84), but not - as by definition - by using total phytoplankton absorption, because during nutrient-limited growth the concentrations of non-fluorescent light-absorbing pigments increased. As a consequence, none of the three proxies (C : Chl, Fv/Fm, φ) was correlated to carbon or cellular phytoplankton growth rates. Therefore, it is concluded that although satellite derived estimates of chlorophyll biomass may be accurate, physiologically-induced non-linear shifts in growth rate proxies may obscure accurate phytoplankton growth rates and hence global carbon production estimates.

  8. Optical trapping of nanoscale plasmonic optical lattice in microfluidic environments

    NASA Astrophysics Data System (ADS)

    Hung, Chia-Chun; Huang, Jer-Shing; Yang, Ya-Tang

    2014-09-01

    Recent advances in optical manipulation have made it an ideal tool to create one, two, and three dimensional periodic optical potential. Such periodic potentials have found interesting technological and fundamental applications such as micro particle sorting and optical fractionation. Plasmon enhanced optical trapping techniques using metallic nanostructures can overcome the diffraction limits of far-field optical trap techniques and therefore permit trapping of nanoparticle with deep sub wavelength dimensions. Here we report the trapping of nanoparticles for a plasmon-enhanced two dimensional optical lattice integrated with microfluidic chip. We observe the trapping of nanoparticles over such an optical lattice. Such an integrated device allows the directional control of nano particles and provides a suitable platform for stochastic transport experiment such as nanoscale optical sorting.

  9. Effects of in-medium cross sections and optical potential on thermal-source formation in p+{sup 197}Au reactions at 6.2-14.6 GeV/c

    SciTech Connect

    Turbide, S.; Beaulieu, L.; Roy, R.; Danielewicz, P.; Huang, R.; Lynch, W.G.; Tsang, M.B.; Xi, H.; Viola, V.E.; Kwiatkowski, K.; Hsi, W.-C.; Wang, G.; Lefort, T.; Bracken, D.S.; Cornell, E.; Ginger, D.S.; Breuer, H.; Gimeno-Nogues, F.; Ramakrishnan, E.; Rowland, D.

    2004-07-01

    Effects of in-medium cross sections and of optical potential on preequilibrium emission and on formation of a thermal source are investigated by comparing the results of transport simulations with experimental results from the p+{sup 197}Au reaction at 6.2-14.6 GeV/c. The employed transport model includes light-composite-particle production and allows for inclusion of in-medium particle-particle cross-section reduction and of momentum dependence in the particle optical potentials. Compared to the past, the model incorporates improved parametrizations of elementary high-energy processes. The simulations indicate that the majority of energy deposition occurs during the first 25 fm/c of a reaction. This is followed by a preequilibrium emission and readjustment of system density and momentum distribution toward an equilibrated system. Within different variants of calculations, the best agreement with data, on the d/p and t/p yield ratios and on the residue mass and charge numbers, is obtained at the time of about 65 fm/c from the start of a reaction, for simulations employing reduced in-medium cross sections and momentum-dependent optical potentials. By that time, the preequilibrium nucleon and cluster emission, as well as mean field readjustments, drive the system to a state of depleted average density, {rho}/{rho}{sub 0}{approx}1/4-1/3 for central collisions, and low-to-moderate excitation, i.e., the region of nuclear liquid-gas phase transition.

  10. Organic Materials For Optical Switching

    NASA Technical Reports Server (NTRS)

    Cardelino, Beatriz H.

    1993-01-01

    Equations predict properties of candidate materials. Report presents results of theoretical study of nonlinear optical properties of organic materials. Such materials used in optical switching devices for computers and telecommunications, replacing electronic switches. Optical switching potentially offers extremely high information throughout in compact hardware.

  11. Preparation of hybrid devices containing nylon/M(II)Pc-TTF (M=Cu, Zn) films with potential optical and electrical applications

    NASA Astrophysics Data System (ADS)

    Sánchez-Vergara, María Elena; López-Romero, Diana Monserrat; Vidal-García, Pablo; Jiménez-Jarquín, Christian; Hernandez-García, Aline; Jiménez-Sandoval, Omar

    2017-05-01

    Hybrid devices consisting of metallophthalocyanines, MPcs (M=Zn, Cu), doped with a Tetrathiafulvalene (TTF) derivative and dispersed in nylon 11 have been prepared by using a thermal evaporation technique. The effects of thermal relaxation on the structure and morphology of the samples were studied by FT-IR spectroscopy, SEM and X-ray diffraction. The thermal relaxation in nylon 11 produced a crystalline arrangement in the α- and β-form MPc molecules. Changes in conductivity of the devices suggest the formation of alternative paths for carrier conduction. It was found that the temperature-dependent electric current in Zn devices showed a semiconductor behavior. Finally, the optical direct and indirect band gap of these hybrid devices was evaluated from optical absorption measurements. The band gap values were found to decrease from 3.7 to 1.38 eV (for the ZnPc device), and from 1.9 to 1.1 eV (for the CuPc device), with the addition of TTF in the polymeric matrix. [Figure not available: see fulltext.

  12. Synthesis, growth, structural, spectral, thermal, chemical etching, linear and nonlinear optical and mechanical studies of an organic single crystal 4-chloro 4-nitrostilbene (CONS): a potential NLO material.

    PubMed

    Dinakaran, Paul M; Kalainathan, S

    2013-07-01

    4-Chloro 4-nitrostilbene (CONS) a new organic nonlinear optical material has been synthesized. Employing slow evaporation method, good optical quality single crystals (dimensions up to 6×2×3 mm(3)) have been grown using ethyl methyl ketone (EMK) as a solvent. The grown crystals have been subjected to various characterizations such as single crystal X-ray diffraction, powder XRD, Fourier Transform Infrared spectroscopy (FTIR), proton NMR, solid UV absorption, SHG studies. Single crystal X-ray diffraction reveals that the crystal system belongs to monoclinic with noncentrosymmetric space group P21. The UV-Vis absorption spectrum has been recorded and found that the cut off wavelength is 380 nm. Functional groups and the structure of the title compound have been confirmed by FTIR and (1)H NMR spectroscopic analyses respectively. Molecular mass of the CONS confirmed by the high resolution mass spectral analysis .The thermal behavior of the grown crystal has been studied by TG/DTA analysis and it shows the melting point is at 188.66 °C. Dislocations and growth pattern present in the grown crystal revealed by the etching study. The mechanical strength of the CONS crystal has been studied by Vicker's hardness measurement. The SHG efficiency of the grown crystal has been determined by Kurtz and Perry powder test which revealed that the CONS crystal (327 mV) has 15 times greater efficiency than that of KDP (21.7 mV).

  13. Synthesis, growth, structural, spectral, thermal, chemical etching, linear and nonlinear optical and mechanical studies of an organic single crystal 4-chloro 4-nitrostilbene (CONS): A potential NLO material

    NASA Astrophysics Data System (ADS)

    Dinakaran, Paul M.; Kalainathan, S.

    2013-07-01

    4-Chloro 4-nitrostilbene (CONS) a new organic nonlinear optical material has been synthesized. Employing slow evaporation method, good optical quality single crystals (dimensions up to 6 × 2 × 3 mm3) have been grown using ethyl methyl ketone (EMK) as a solvent. The grown crystals have been subjected to various characterizations such as single crystal X-ray diffraction, powder XRD, Fourier Transform Infrared spectroscopy (FTIR), proton NMR, solid UV absorption, SHG studies. Single crystal X-ray diffraction reveals that the crystal system belongs to monoclinic with noncentrosymmetric space group P21. The UV-Vis absorption spectrum has been recorded and found that the cut off wavelength is 380 nm. Functional groups and the structure of the title compound have been confirmed by FTIR and 1H NMR spectroscopic analyses respectively. Molecular mass of the CONS confirmed by the high resolution mass spectral analysis .The thermal behavior of the grown crystal has been studied by TG/DTA analysis and it shows the melting point is at 188.66 °C. Dislocations and growth pattern present in the grown crystal revealed by the etching study. The mechanical strength of the CONS crystal has been studied by Vicker's hardness measurement. The SHG efficiency of the grown crystal has been determined by Kurtz and Perry powder test which revealed that the CONS crystal (327 mV) has 15 times greater efficiency than that of KDP (21.7 mV).

  14. Preparation of hybrid devices containing Nylon/M(II)Pc-TTF (M=Cu, Zn) films with potential optical and electrical applications

    NASA Astrophysics Data System (ADS)

    Sánchez-Vergara, María Elena; López-Romero, Diana Monserrat; Vidal-García, Pablo; Jiménez-Jarquín, Christian; Hernandez-García, Aline; Jiménez-Sandoval, Omar

    2017-03-01

    Hybrid devices consisting of metallophthalocyanines, MPcs (M=Zn, Cu), doped with a Tetrathiafulvalene (TTF) derivative and dispersed in nylon 11 have been prepared by using a thermal evaporation technique. The effects of thermal relaxation on the structure and morphology of the samples were studied by FT-IR spectroscopy, SEM and X-ray diffraction. The thermal relaxation in nylon 11 produced a crystalline arrangement in the α- and β-form MPc molecules. Changes in conductivity of the devices suggest the formation of alternative paths for carrier conduction. It was found that the temperature-dependent electric current in Zn devices showed a semiconductor behavior. Finally, the optical direct and indirect band gap of these hybrid devices was evaluated from optical absorption measurements. The band gap values were found to decrease from 3.7 to 1.38 eV (for the ZnPc device), and from 1.9 to 1.1 eV (for the CuPc device), with the addition of TTF in the polymeric matrix. [Figure not available: see fulltext.

  15. Nonlinear optics in optical-fiber nanowires and their applications

    NASA Astrophysics Data System (ADS)

    Xu, Fei; Wu, Zhen-xing; Lu, Yan-qing

    2017-09-01

    We review recent research on nonlinear optical interactions in optical-fiber nanowires (OFNs) with sub-micron transverse dimensions. Such OFNs, which are fabricated from standard optical fibers, offer numerous beneficial optical and mechanical properties, including strong evanescent fields, high flexibility and configurability, a small mass, and low-loss interconnection to other optical fibers and fiberized components. In particular, the strong confinement of light enables a large enhancement of nonlinear interactions and group-velocity dispersion engineering. The combination of these properties makes OFNs ideal for many nonlinear optical applications, including harmonic generation, Brillouin scattering, four-wave mixing, supercontinuum generation, and optomechanics. With the incorporation of new materials, OFNs should be ideally suited for a host of nonlinear optical interactions and devices and offer great potential in miniature fiber devices for optical telecommunications and optical sensor applications.

  16. Exploring the potential of boron-doped nanographene as efficient charge transport and nonlinear optical material: A first-principles study.

    PubMed

    Irfan, Ahmad; Chaudhry, Aijaz Rasool; Muhammad, Shabbir; Al-Sehemi, Abdullah G

    2017-08-01

    Owing to their excellent electrochemical properties, graphenes found applications in several fields ranging from semiconductors, solar cells, field effect transistors, and nanoscale electronic devices as well as in nonlinear optical (NLO) applications. The structural features, electro-optical, charge transport and nonlinear optical properties of the boron-doped graphene (BG) compound 1 were studied using density functional theory methods The BG compound comprises a central electron deficient site of boron atoms, which can serve as electron acceptor while terminal alkoxy groups as donors leading to powerful donor-π-acceptor (D-π-A) configuration. The experimental crystal structure was successfully reproduced by optimized ground state geometry at PBE0/6-311G* level of theory for isolated molecule. The experimental lattice parameters, geometries, crystal presentation and alignment of molecules in the unit cells as well as their packing orientation of BG compound 1 was also efficiently reproduced by applying periodic boundary conditions (PBC) at PBE level. The comprehensive intramolecular charge transfer (CT) was realized from terminal rings of the HOMO to the electron deficient sites of boron atoms of the LUMO. The nature of BG compound 1 might be more towards hole transport even though its hole reorganization energy is twice than that of the electron one due to the significant higher hole transfer integral values. The superior hole transfer integrals and intrinsic mobility values of the BG compound 1 might lead remarkable hole transport contender as compared to many other organic materials. The narrow band gap, density of states profile, dielectric function, uniform conductivity functions and noteworthy electronic as well as CT properties revealed that the BG compound 1 might be proficient optoelectronic contestant having intermolecular CT as well as intramolecular CT with optimal stability. A comparison of static third-order polarizability <γ> of BG compound 1

  17. Analysis of {sup 4}He+{sup 40}Ca and {sup 4}He+{sup 44}Ti scattering using different optical model potentials

    SciTech Connect

    Ibraheem, Awad A.

    2016-09-15

    Elastic scattering of {sup 4}He+{sup 40}Ca and {sup 4}He+{sup 44}Ti reactions at backward angles has been analyzed using two different models, microscopic and semimicroscopic folding potentials. The derived real potentials supplemented with phenomenological Woods–Saxon imaginary potentials, provide good agreement with the experimental data at energy E{sub c.m.} = 21.8 MeV without need to renormalize the potentials. Coupled channels calculations are used to extract the inelastic scattering cross section to the low-lying state 2+ (1.083 MeV) of {sup 44}Ti. The deformation length is obtained and compared with the electromagnetic measurement values as well as those obtained from previous studies.

  18. Assessing the utility of autofluorescence-based pulmonary optical endomicroscopy to predict the malignant potential of solitary pulmonary nodules in humans

    PubMed Central

    Seth, Sohan; Akram, Ahsan R.; McCool, Paul; Westerfeld, Jody; Wilson, David; McLaughlin, Stephen; Dhaliwal, Kevin; Williams, Christopher K. I.

    2016-01-01

    Solitary pulmonary nodules are common, often incidental findings on chest CT scans. The investigation of pulmonary nodules is time-consuming and often leads to protracted follow-up with ongoing radiological surveillance, however, clinical calculators that assess the risk of the nodule being malignant exist to help in the stratification of patients. Furthermore recent advances in interventional pulmonology include the ability to both navigate to nodules and also to perform autofluorescence endomicroscopy. In this study we assessed the efficacy of incorporating additional information from label-free fibre-based optical endomicrosopy of the nodule on assessing risk of malignancy. Using image analysis and machine learning approaches, we find that this information does not yield any gain in predictive performance in a cohort of patients. Further advances with pulmonary endomicroscopy will require the addition of molecular tracers to improve information from this procedure. PMID:27550539

  19. Assessing the utility of autofluorescence-based pulmonary optical endomicroscopy to predict the malignant potential of solitary pulmonary nodules in humans

    NASA Astrophysics Data System (ADS)

    Seth, Sohan; Akram, Ahsan R.; McCool, Paul; Westerfeld, Jody; Wilson, David; McLaughlin, Stephen; Dhaliwal, Kevin; Williams, Christopher K. I.

    2016-08-01

    Solitary pulmonary nodules are common, often incidental findings on chest CT scans. The investigation of pulmonary nodules is time-consuming and often leads to protracted follow-up with ongoing radiological surveillance, however, clinical calculators that assess the risk of the nodule being malignant exist to help in the stratification of patients. Furthermore recent advances in interventional pulmonology include the ability to both navigate to nodules and also to perform autofluorescence endomicroscopy. In this study we assessed the efficacy of incorporating additional information from label-free fibre-based optical endomicrosopy of the nodule on assessing risk of malignancy. Using image analysis and machine learning approaches, we find that this information does not yield any gain in predictive performance in a cohort of patients. Further advances with pulmonary endomicroscopy will require the addition of molecular tracers to improve information from this procedure.

  20. Quantitative Agreement between Electron-Optical Phase Images of WSe2 and Simulations Based on Electrostatic Potentials that Include Bonding Effects

    NASA Astrophysics Data System (ADS)

    Borghardt, S.; Winkler, F.; Zanolli, Z.; Verstraete, M. J.; Barthel, J.; Tavabi, A. H.; Dunin-Borkowski, R. E.; Kardynal, B. E.

    2017-02-01

    The quantitative analysis of electron-optical phase images recorded using off-axis electron holography often relies on the use of computer simulations of electron propagation through a sample. However, simulations that make use of the independent atom approximation are known to overestimate experimental phase shifts by approximately 10%, as they neglect bonding effects. Here, we compare experimental and simulated phase images for few-layer WSe2 . We show that a combination of pseudopotentials and all-electron density functional theory calculations can be used to obtain accurate mean electron phases, as well as improved atomic-resolution spatial distribution of the electron phase. The comparison demonstrates a perfect contrast match between experimental and simulated atomic-resolution phase images for a sample of precisely known thickness. The low computational cost of this approach makes it suitable for the analysis of large electronic systems, including defects, substitutional atoms, and material interfaces.

  1. The potential of computer vision, optical backscattering parameters and artificial neural network modelling in monitoring the shrinkage of sweet potato (Ipomoea batatas L.) during drying.

    PubMed

    Onwude, Daniel I; Hashim, Norhashila; Abdan, Khalina; Janius, Rimfiel; Chen, Guangnan

    2017-07-30

    Drying is a method used to preserve agricultural crops. During the drying of products with high moisture content, structural changes in shape, volume, area, density and porosity occur. These changes could affect the final quality of dried product and also the effective design of drying equipment. Therefore, this study investigated a novel approach in monitoring and predicting the shrinkage of sweet potato during drying. Drying experiments were conducted at temperatures of 50-70 °C and samples thicknesses of 2-6 mm. The volume and surface area obtained from camera vision, and the perimeter and illuminated area from backscattered optical images were analysed and used to evaluate the shrinkage of sweet potato during drying. The relationship between dimensionless moisture content and shrinkage of sweet potato in terms of volume, surface area, perimeter and illuminated area was found to be linearly correlated. The results also demonstrated that the shrinkage of sweet potato based on computer vision and backscattered optical parameters is affected by the product thickness, drying temperature and drying time. A multilayer perceptron (MLP) artificial neural network with input layer containing three cells, two hidden layers (18 neurons), and five cells for output layer, was used to develop a model that can monitor, control and predict the shrinkage parameters and moisture content of sweet potato slices under different drying conditions. The developed ANN model satisfactorily predicted the shrinkage and dimensionless moisture content of sweet potato with correlation coefficient greater than 0.95. Combined computer vision, laser light backscattering imaging and artificial neural network can be used as a non-destructive, rapid and easily adaptable technique for in-line monitoring, predicting and controlling the shrinkage and moisture changes of food and agricultural crops during drying. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

  2. Optical microspectrometer

    DOEpatents

    Sweatt, William C.; Christenson, Todd R.

    2004-05-25

    An optical microspectrometer comprises a grism to disperse the spectra in a line object. A single optical microspectrometer can be used to sequentially scan a planar object, such as a dye-tagged microchip. Because the optical microspectrometer is very compact, multiple optical microspectrometers can be arrayed to provide simultaneous readout across the width of the planar object The optical microspectrometer can be fabricated with lithographic process, such as deep X-ray lithography (DXRL), with as few as two perpendicular exposures.

  3. Optically tunable optical filter

    NASA Astrophysics Data System (ADS)

    James, Robert T. B.; Wah, Christopher; Iizuka, Keigo; Shimotahira, Hiroshi

    1995-12-01

    We experimentally demonstrate an optically tunable optical filter that uses photorefractive barium titanate. With our filter we implement a spectrum analyzer at 632.8 nm with a resolution of 1.2 nm. We simulate a wavelength-division multiplexing system by separating two semiconductor laser diodes, at 1560 nm and 1578 nm, with the same filter. The filter has a bandwidth of 6.9 nm. We also use the same filter to take 2.5-nm-wide slices out of a 20-nm-wide superluminescent diode centered at 840 nm. As a result, we experimentally demonstrate a phenomenal tuning range from 632.8 to 1578 nm with a single filtering device.

  4. Optical label-free and model-free probe of the surface potential of nanoscale and microscopic objects in aqueous solution

    NASA Astrophysics Data System (ADS)

    Lütgebaucks, Cornelis; Gonella, Grazia; Roke, Sylvie

    2016-11-01

    The electrostatic environment of aqueous systems is an essential ingredient for the function of any living system. To understand the electrostatic properties and their molecular foundation in soft, living, and three-dimensional systems, we developed a table-top model-free method to determine the surface potential of nano- and microscopic objects in aqueous solutions. Angle-resolved nonresonant second harmonic (SH) scattering measurements contain enough information to determine the surface potential unambiguously, without making assumptions on the structure of the interfacial region. The scattered SH light that is emitted from both the particle interface and the diffuse double layer can be detected in two different polarization states that have independent scattering patterns. The angular shape and intensity are determined by the surface potential and the second-order surface susceptibility. Calibrating the response with the SH intensity of bulk water, a single, unique surface potential value can be extracted. We demonstrate the method with 80 nm bare oil droplets in water and ˜50 nm dioleoylphosphatidylcholine (DOPC) and dioleoylphosphatidylserine (DOPS) liposomes at various ionic strengths.

  5. The potential offered by real-time, high-sensitivity monitoring of ethane in breath and some pilot studies using optical spectroscopy

    NASA Astrophysics Data System (ADS)

    Skeldon, Kenneth D.; Patterson, Claire; Wyse, Cathy A.; Gibson, Graham M.; Padgett, Miles J.; Longbottom, Chris; McMillan, Lesley C.

    2005-06-01

    Breath analysis applied to biomedical applications has gained much momentum is recent years due to the growing research demonstrating that breath gas can provide clinically useful data. Particularly exciting is the area of real-time breath analysis which, when coupled with appropriately chosen target species, can offer a novel method for non-invasive patient monitoring. Here we describe the role of ethane, a breath gas of universal appeal in assessing in vivo oxidative stress (cell damage). We first present a review of emerging applications where real-time ethane monitoring could yield original new results for healthcare. We then report on results from a portable ethane spectroscopy system (accuracy better then 100 parts per trillion (1 part in 1010) over a 1 s time response) that we have developed to exploit some of these applications. By presenting some initial results from pilot studies in the life sciences, we comment on the requirements that the next stage of optical spectroscopy technology has to meet in order to benefit clinical end-users.

  6. NIR emission at 1.53 μm in Er3+ doped lead free zinc phosphate glasses for potential broadband optical amplifiers

    NASA Astrophysics Data System (ADS)

    Prasad, V. Reddy; Damodaraiah, S.; Ratnakaram, Y. C.

    2017-05-01

    Er3+ doped zinc phosphate glasses with chemical compositions (60-x) NH4H2PO4 + 20ZnO+10BaF2+10NaF+xRE (where RE=Er2O3, x = 0.1, 0.5, 1.0, 1.5 and 2.0 mol%) have been prepared by melt quenching technique. Amorphous structure was ascertained by XRD analysis. The functional bands have been assigned and clearly elucidated by FT-IR spectral profiles for host glass sample. Judd-Ofelt (J-O) intensity parameters (Ωλ: λ=2, 4, 6) have been obtained from the spectral intensities of different absorption bands of Er3+ ion through optical absorption spectra. NIR photoluminescence spectra exhibited one emission band (4I15/2→4I13/2) of Er3+ ions. These glasses were suggested as suitable hosts for efficient lasing action in NIR region at 1534 nm for Er3+ ion.

  7. Digital optical conversion module

    DOEpatents

    Kotter, Dale K.; Rankin, Richard A.

    1991-02-26

    A digital optical conversion module used to convert an analog signal to a computer compatible digital signal including a voltage-to-frequency converter, frequency offset response circuitry, and an electrical-to-optical converter. Also used in conjunction with the digital optical conversion module is an optical link and an interface at the computer for converting the optical signal back to an electrical signal. Suitable for use in hostile environments having high levels of electromagnetic interference, the conversion module retains high resolution of the analog signal while eliminating the potential for errors due to noise and interference. The module can be used to link analog output scientific equipment such as an electrometer used with a mass spectrometer to a computer.

  8. Digital optical conversion module

    DOEpatents

    Kotter, D.K.; Rankin, R.A.

    1988-07-19

    A digital optical conversion module used to convert an analog signal to a computer compatible digital signal including a voltage-to-frequency converter, frequency offset response circuitry, and an electrical-to-optical converter. Also used in conjunction with the digital optical conversion module is an optical link and an interface at the computer for converting the optical signal back to an electrical signal. Suitable for use in hostile environments having high levels of electromagnetic interference, the conversion module retains high resolution of the analog signal while eliminating the potential for errors due to noise and interference. The module can be used to link analog output scientific equipment such as an electrometer used with a mass spectrometer to a computer. 2 figs.

  9. Full potential study of the elastic, electronic, and optical properties of spinels MgIn{sub 2}S{sub 4} and CdIn{sub 2}S{sub 4} under pressure effect

    SciTech Connect

    Semari, F.; Khenata, R.; Rabah, M.; Bouhemadou, A.; Bin Omran, S.; Reshak, Ali H.; Rached, D.

    2010-12-15

    The structural, elastic, electronic, and optical properties of cubic spinel MgIn{sub 2}S{sub 4} and CdIn{sub 2}S{sub 4} compounds have been calculated using a full relativistic version of the full-potential linearized-augmented plane wave with the mixed basis FP/APW+lo method. The exchange and correlation potential is treated by the generalized-gradient approximation (GGA). Moreover, the Engel-Vosko GGA formalism is also applied to optimize the corresponding potential for band structure calculations. The ground state properties, including the lattice constants, the internal parameter, the bulk modulus, and the pressure derivative of the bulk modulus are in reasonable agreement with the available data. Using the total energy-strain technique, we have determined the full set of first-order elastic constants C{sub ij} and their pressure dependence, which have not been calculated or measured yet. The shear modulus, Young's modulus, and Poisson's ratio are calculated for polycrystalline XIn{sub 2}S{sub 4} aggregates. The Debye temperature is estimated from the average sound velocity. Electronic band structures show a direct band gap ({Gamma}-{Gamma}) for MgIn{sub 2}S{sub 4} and an indirect band gap (K-{Gamma}) for CdIn{sub 2}S{sub 4}. The calculated band gaps with EVGGA show a significant improvement over the GGA. The optical constants, including the dielectric function {epsilon}({omega}), the refractive index n({omega}), the reflectivity R({omega}), and the energy loss function L({omega}) were calculated for radiation up to 30 eV. -- Graphical abstract: Calculated total and partial densities of states for MgIn{sub 2}S{sub 4} and CdIn{sub 2}S{sub 4}

  10. Interannual variability of summertime aerosol optical depth over East Asia during 2000-2011: a potential influence from El Niño Southern Oscillation

    NASA Astrophysics Data System (ADS)

    Liu, Yikun; Liu, Junfeng; Tao, Shu

    2013-12-01

    Aerosols degrade air quality, perturb atmospheric radiation, and impact regional and global climate. Due to the rapid increase in anthropogenic emissions, aerosol loading over East Asia (EA) is markedly higher than other industrialized regions, which motivates a need to characterize the evolution of aerosols and understand the associated drivers. Based on the MISR satellite data during 2000-2011, a wave-like interannual variation of summertime aerosol optical depth (SAOD) is observed over the highly populated North China Plain (NCP) in East Asia. Specifically, the peak-to-trough ratio of SAOD ranges from 1.4 to 1.6, with a period of 3-4 years. This variation pattern differs apparently from what has been seen in EA emissions, indicating a periodic change in regional climate pattern during the past decade. Investigations of meteorological fields over the region reveal that the high SAOD is generally associated with the enhanced Philippine Sea Anticyclone Anomaly (PSAA) which weakens southeasterlies over northeastern EA and depresses air ventilation. Alternatively, higher temperature and lower relative humidity are found to be coincident with reduced SAOD. The behavior of PSAA has been found previously to be modulated by the El Niño Southern Oscillations (ENSO), therefore ENSO could disturb the EA SAOD as well. Rather than changing coherently with the ENSO activity, the SAOD peaks over NCP are found to be accompanied by the rapid transition of El Niño warm to cold phases developed four months ahead. An index measuring the development of ENSO during January-April is able to capture the interannual variability of SAOD over NCP during 2000-2011. This finding indicates a need to integrate the large-scale periodic climate variability in the design of regional air quality policy.

  11. Intense orange emission in Pr3+ and NIR emission at 1.53 μm in Er3+ doped zinc phosphate glasses for potential broadband optical amplifier

    NASA Astrophysics Data System (ADS)

    Reddy Prasad, V.; Damodaraiah, S.; Seshadri, M.; Babu, S.; Ratnakaram, Y. C.

    2017-10-01

    Praseodymium (Pr3+) and Erbium (Er3+) doped zinc phosphate glasses with chemical compositions (60 - x) NH4H2PO4 + 20ZnO + 10BaF2 + 10NaF + xRE (where RE = Pr6O11 and Er2O3, x = 0.1, 0.5, 1.0, 1.5 and 2.0 mol%) have been prepared by melt quenching technique. Amorphous structure was ascertained by XRD analysis. The functional and vibrational bands have been assigned and clearly elucidated by FT-IR and Raman spectral profiles for all the glass samples. Judd-Ofelt (J-O) intensity parameters ( Ω λ : λ = 2, 4, 6) have been obtained from the spectral intensities of different absorption bands of Pr3+ and Er3+ ions through optical absorption spectra. The radiative properties such as radiative transition probabilities ( A R ), radiative lifetimes ( τ R ) and branching ratios ( β R ) for different excited states were calculated by using J-O intensity parameters. Visible photoluminescence spectra have exhibited six emission bands (3P1 → 3H5, 1D2 → 3H4, 3P0 → 3F2, 3P1 → 3F3, 3P0 → 3F3 and 3P0 → 3F4 states) for all the concentrations of Pr3+ ions. NIR photoluminescence spectra exhibited one emission band (4I15/2 → 4I13/2) of Er3+ ions. The energy transfer mechanism that leads to the quenching of lifetimes of 1D2 and 4I13/2 states have been discussed at higher concentrations of Pr3+ and Er3+ ions, respectively. These glasses were suggested as suitable hosts to produce intense orange emission at 608 nm for Pr3+ ion and efficient lasing action in NIR region at 1534 nm for Er3+ ion.

  12. Characterization of optically stimulated luminescence dosimeters and investigating their potential for estimating pediatric organ doses in multi-slice computed tomography

    NASA Astrophysics Data System (ADS)

    Al-Senan, Rani Mohammed

    Recent epidemiologic studies have shown a strong association between the relatively high doses of pediatric CT and the risk of cancer. Quantifying organ doses, as a measure of the risk, is commonly based on either direct anthropomorphic phantom measurements or Monte Carlo simulation. The major disadvantage in the phantom approach is its high cost especially that, for pediatric CT dosimetry, various phantom sizes are required to represent different age groups of children. On the other hand, Monte Carlo simulation, although not considered costly, requires validation by anthropomorphic phantom measurements. The aim of this project was to develop two methods of organ dose estimation in pediatric CT: 1) from the measured surface dose using optically stimulated luminescence dosimeters (OSLDs) and 2) by measuring the circumference of the body part being scanned as well as knowing the scan parameters. The project was based on a study proposed by the surgery department to monitor radiation exposure to children during their CT examination in the ER. A total of 200 pediatric patients were enrolled in this study which used OSLDs to monitor the doses. Specific aim 1 of this project was to characterize the OSLDs in the diagnostic energy range. Specific aim 2(a) was to find relationships between the patients' doses from OSLDs and both scan CTDI and the measured circumference. In specific aim 2(b) we carried out measurements using CTDI phantoms to investigate the relationships studied in specific aim 2(a). Specific aim 3 was to come up with models to estimate select organ doses from measuring surface dose or by using the circumference of the body part. To do this, pediatric examinations were simulated using a set of pediatric anthropomorphic phantoms in which doses of select organs were measured.

  13. Electro-Optic Modulator.

    DTIC Science & Technology

    An electro - optic modulator is used to modulate coherent light beams by the application of an electric potential. It combines a Fabry-Perot etalon and...a diffraction grating in a single unit. An etalon is constructed with an electro - optic material between reflecting surfaces. A voltage applied...between alternate, spaced-apart electrodes of a metal grid attached to one reflecting surface induces a diffraction grating in the electro optic material. Light entering the etalon is diffracted, reflected and efficiently coupled out.

  14. Optical Communications

    ERIC Educational Resources Information Center

    Young, Matt

    1973-01-01

    Describes the characteristics and operational problems of optical waveguides, and concludes that the wide use of optical communications can be expected if difficulties in commercial production of components can be eliminated. (CC)

  15. Optical Communications

    ERIC Educational Resources Information Center

    Young, Matt

    1973-01-01

    Describes the characteristics and operational problems of optical waveguides, and concludes that the wide use of optical communications can be expected if difficulties in commercial production of components can be eliminated. (CC)

  16. Optical Solitons

    NASA Astrophysics Data System (ADS)

    Taylor, J. R.

    2005-08-01

    1. Optical solitons in fibres: theoretical review A. Hasegawa; 2. Solitons in optical fibres: an experimental account L. F. Mollenauer; 3. All-optical long-distance soliton-based transmission systems K. Smith and L. F. Mollenauer; 4. Nonlinear propagation effects in optical fibres: numerical studies K. J. Blow and N. J. Doran; 5. Soliton-soliton interactions C. Desem and P. L. Chu; 6. Soliton amplification in erbium-doped fibre amplifiers and its application to soliton communication M. Nakazawa; 7. Nonlinear transformation of laser radiation and generation of Raman solitons in optical fibres E. M. Dianov, A. B. Grudinin, A. M. Prokhorov and V. N. Serkin; 8. Generation and compression of femtosecond solitons in optical fibers P. V. Mamyshev; 9. Optical fibre solitons in the presence of higher order dispersion and birefringence C. R. Menyuk and Ping-Kong A. Wai; 10. Dark optical solitons A. M. Weiner; 11. Soliton Raman effects J. R. Taylor; Bibliography; Index.

  17. Optical Solitons

    NASA Astrophysics Data System (ADS)

    Taylor, J. R.

    1992-04-01

    1. Optical solitons in fibres: theoretical review A. Hasegawa; 2. Solitons in optical fibres: an experimental account L. F. Mollenauer; 3. All-optical long-distance soliton-based transmission systems K. Smith and L. F. Mollenauer; 4. Nonlinear propagation effects in optical fibres: numerical studies K. J. Blow and N. J. Doran; 5. Soliton-soliton interactions C. Desem and P. L. Chu; 6. Soliton amplification in erbium-doped fibre amplifiers and its application to soliton communication M. Nakazawa; 7. Nonlinear transformation of laser radiation and generation of Raman solitons in optical fibres E. M. Dianov, A. B. Grudinin, A. M. Prokhorov and V. N. Serkin; 8. Generation and compression of femtosecond solitons in optical fibers P. V. Mamyshev; 9. Optical fibre solitons in the presence of higher order dispersion and birefringence C. R. Menyuk and Ping-Kong A. Wai; 10. Dark optical solitons A. M. Weiner; 11. Soliton Raman effects J. R. Taylor; Bibliography; Index.

  18. Optical probe

    DOEpatents

    Hencken, Kenneth; Flower, William L.

    1999-01-01

    A compact optical probe is disclosed particularly useful for analysis of emissions in industrial environments. The instant invention provides a geometry for optically-based measurements that allows all optical components (source, detector, rely optics, etc.) to be located in proximity to one another. The geometry of the probe disclosed herein provides a means for making optical measurements in environments where it is difficult and/or expensive to gain access to the vicinity of a flow stream to be measured. Significantly, the lens geometry of the optical probe allows the analysis location within a flow stream being monitored to be moved while maintaining optical alignment of all components even when the optical probe is focused on a plurality of different analysis points within the flow stream.

  19. Growth and characterization of noncentrosymmetric single crystals of L-Argininium-4-nitro Phenolate Monohydrate (LARP): A potential second order nonlinear optical material

    NASA Astrophysics Data System (ADS)

    Saravanan, M.; Senthil, A.; Rajasekar, S. Abraham

    2015-10-01

    A potential second order NLO material L-Argininium-4-nitro Phenolate Monohydrate (LARP) was grown by the slow evaporation technique. The grown organic NLO crystals were subjected to various studies such as single crystal XRD, UV-Visible spectrum, photoluminescence, Second Harmonic Generation (for various particle sizes) and laser damage threshold (LDT) studies. The LARP crystal belongs to orthorhombic system with noncentrosymmetric space group P212121. Piezoelectric charge coefficients of the grown crystal have been determined. The dielectric studies were performed at different temperatures and frequencies to analyze the electrical properties. The microhardness measurements were used to investigate the mechanical property of the grown crystal.

  20. Optical cryocooling of diamond

    NASA Astrophysics Data System (ADS)

    Kern, M.; Jeske, J.; Lau, D. W. M.; Greentree, A. D.; Jelezko, F.; Twamley, J.

    2017-06-01

    The cooling of solids by optical means only using anti-Stokes emission has a long history of research and achievements. Such cooling methods have many advantages ranging from no moving parts or fluids through to operation in vacuum and may have applications to cryosurgery. However, achieving large optical cryocooling powers has been difficult to manage except in certain rare-earth crystals but these are mostly toxic and not biocompatible. Through study of the emission and absorption cross sections we find that diamond, containing either nitrogen vacancy (NV) or silicon vacancy defects, shows potential for optical cryocooling and, in particular, NV doping shows promise for optical refrigeration. We study the optical cooling of doped diamond microcrystals ranging 10-250 μ m in diameter trapped either in vacuum or in water. For the vacuum case we find NV-doped microdiamond optical cooling below room temperature could exceed |Δ T |>10 K for irradiation powers of Pin<100 mW. We predict that such temperature changes should be easily observed via large alterations in the diffusion constant for optically cryocooled microdiamonds trapped in water in an optical tweezer or via spectroscopic signatures such as the zero-phonon line width or Raman line.