Science.gov

Sample records for a1 lo mode

  1. Mode sequence, frequency change of nonsoft phonons, and LO-TO splitting in strained tetragonal BaTiO3

    NASA Astrophysics Data System (ADS)

    Raeliarijaona, Aldo; Fu, Huaxiang

    2015-09-01

    Ultraviolet Raman spectroscopy revealed the existence of an unusual large-frequency shift occurring to a nonsoft mode of E (TO4 ) when BaTiO3 is strained to a SrTiO3 substrate [D. Tenne et al., Science 313, 1614 (2006), 10.1126/science.1130306]. It raised two interesting questions: (i) whether there are other nonsoft modes that possess similar or even larger strain-induced frequency shifts and (ii) how the mode sequence is altered by these shifts in frequency. Note that mode sequence is also pivotal in correctly indexing and assigning the spectroscopy peaks observed in all Raman experiments. By mapping out the evolutions of individual phonon modes as a function of strain using first-principles density functional perturbation calculations, we determine the mode sequence and strain-induced phonon frequency shifts in prototypical BaTiO3. Our study reveals that the mode sequence is drastically different when BaTiO3 is strained to SrTiO3 compared to that in the unstrained structure, caused by multiple mode crossings. Furthermore, we predict that three other nonsoft modes, A1(TO2), E (LO4 ), and A1(TO3), display even larger strain-induced frequency shifts than E (TO4 ). The strain responses of individual modes are found to be highly mode specific, and a mechanism that regulates the magnitude of the frequency shift is provided. As another key outcome of this study, we tackle a long-standing problem of LO-TO splitting in ferroelectrics. A rigorous definition for the LO-TO splitting is formulated, which allows this critical quantity to be calculated quantitatively. The definition immediately reveals a new finding; that is, a large LO-TO splitting not only exists for E (LO4 ), which is previously known and originates from a soft mode, it also occurs for a nonsoft A1(LO3) mode. The LO-TO splitting is shown to decrease drastically with compressive strain, and this decrease cannot be explained by the Born effective charges and high-frequency dielectric constants.

  2. Resonant Modes in a 1.6 Cells RF Gun

    NASA Astrophysics Data System (ADS)

    Ferrario, Massimo; Ronsivalle, Concetta

    2007-09-01

    The SPARC photoinjector RF gun consists in the BNL/SLAC/UCLA 1.6 cell structure designed to resonate at 2856 MHz in the π mode. It will be demonstrated by a numerical modelization based on SUPERFISH code combined with the LC-circuit analysis that the two oscillating modes of the system usually indicated as 0-mode and π-mode (the operating mode) are in reality a π/3-mode-like and a π-mode-like. The consequences on the definition of the coupling coefficient and on the use of mode-separation based RF measurements are described.

  3. Resonant Modes in a 1.6 Cells RF Gun

    NASA Astrophysics Data System (ADS)

    Ferrario, Massimo; Ronsivalle, Concetta

    The SPARC photoinjector RF gun consists in the BNL/SLAC/UCLA 1.6 cell structure designed to resonate at 2856 MHz in the π mode. It will be demonstrated by a numerical modelization based on SUPERFISH code combined with the LC-circuit analysis that the two oscillating modes of the system usually indicated as 0-mode and π-mode (the operating mode) are in reality a π/3-mode-like and a π-mode-like. The consequences on the definition of the coupling coefficient and on the use of mode-separation based RF measurements are described.

  4. Composition dependence of the in-plane Cu-O bond-stretching LO phonon mode in YBa2Cu3O6+x

    SciTech Connect

    Stercil, F.; Egami, T.; Mook Jr, Herbert A; Yethiraj, Mohana; Chung, J.-H.; Arai, M.; Frost, C.; Dogan, F.

    2008-01-01

    An inelastic pulsed neutron scattering study was performed on the dependence of the dispersion and spectral intensity of the in-plane Cu-O bond-stretching LO phonon mode on doped charge density. The measurements were made in the time-of-flight mode with the multiangle position sensitive spectrometer of the ISIS facility on single crystals of YBa{sub 2}Cu{sub 3}O{sub 6+x} (x=0.15, 0.35, 0.6, 0.7, and 0.95). The focus of the study is the in-plane Cu-O bond-stretching LO phonon mode, which is known for strong electron-phonon coupling and unusual dependence on composition and temperature. It is shown that the dispersions for the samples with x=0.35, 0.6, and 0.7 are similar to the superposition of those for x=0.15 and 0.95 samples, and cannot be explained in terms of the structural anisotropy. It is suggested that the results are consistent with the model of nanoscale electronic phase separation, with the fraction of the phases being dependent on the doped charge density.

  5. Mode crosstalk matrix measurement of a 1  km elliptical core few-mode optical fiber.

    PubMed

    Milione, Giovanni; Ip, Ezra; Li, Ming-Jun; Stone, Jefferey; Peng, Gaozhu; Wang, Ting

    2016-06-15

    The spatial modes of a 1 km elliptical core few-mode optical fiber (6 spatial modes) are analyzed by using liquid crystal on silicon spatial light modulators to measure the fiber's mode crosstalk matrix in Hermite-Gaussian, Laguerre-Gaussian, and linearly polarized spatial mode bases. It is shown that the fiber's spatial modes can be described by Hermite-Gaussian modes, which can propagate 1 km over the optical fiber with <-20  dB (1%) average mode crosstalk even when the fiber has multiple 1 cm diameter bends. The use of elliptical core few-mode optical fibers for space division multiplexing in data centers is discussed. PMID:27304281

  6. Long-wavelength lattice vibrations of Ag3In5Se9 and Ag3In5Te9 single crystals — An inversion of LO- and TO-mode frequencies

    NASA Astrophysics Data System (ADS)

    Gasanly, Nizami Mamed

    2016-06-01

    Infrared (IR) reflectivities are registered in the frequency range of 50-2000 cm‑1 for Ag3In5Se9 and Ag3In5Te9 single crystals grown by Bridgman method. Three infrared-active modes are detected in spectra. The optical parameters, real and imaginary parts of the dielectric function, the function of energy losses, refractive index, absorption index and absorption coefficient were calculated from reflectivity experiments. The frequencies of transverse and longitudinal optical modes (TO and LO modes) and oscillator strength were also determined. The bands detected in infrared spectra were tentatively attributed to various vibration types (valence and valence-deformation). The inversion of LO- and TO-mode frequencies of the sandwiched pair was observed for studied crystals.

  7. Shear mode coupling and tilted grain growth of A1N thin films in BAW resonators.

    PubMed

    Martin, Fabrice; Jan, Marc-Etienne; Rey-Mermet, Samuel; Belgacem, Brahim; Su, Dong; Cantoni, Marco; Muralt, Paul

    2006-07-01

    Polycrystalline A1N thin films were deposited by RF reactive magnetron sputtering on Pt(111)/Ti electrode films. The substrates were tilted by an angle ranging from 40 degrees to 70 degrees with respect to the target normal. A low deposition temperature and a high sputter gas pressure were found ideal for tilted growth. The resulting grain tilt angle amounts to about half the substrate tilt angle. For coupling evaluation, 5 GHz solidly mounted resonator structures have been realized. The tilted grain A1N films exhibited a permittivity in the 9.5-10.5 range and loss tangent of 0.3%. Two shear modes as well as the longitudinal mode could be clearly identified. The coupling coefficient k2(eff) of the fundamental thickness shear mode (TS0) was found to be about 0.5%, which is compatible with a c-axis tilt of about 6 degrees. PMID:16889341

  8. η collective mode as A1 g Raman resonance in cuprate superconductors

    NASA Astrophysics Data System (ADS)

    Montiel, X.; Kloss, T.; Pépin, C.; Benhabib, S.; Gallais, Y.; Sacuto, A.

    2016-01-01

    We discuss the possible existence of a spin singlet excitation with charge ±2 (η mode) originating the A1 g Raman resonance in cuprate superconductors. This η mode relates the d -wave superconducting singlet pairing channel to a d -wave charge channel. We show that the η boson forms a particle-particle bound state below the 2 Δ threshold of the particle-hole continuum where Δ is the maximum d -wave gap. Within a generalized random phase approximation and Bethe-Salpeter approximation study, we find that this mode has energies similar to the resonance observed with inelastic neutron scattering below the superconducting (SC) coherent peak at 2 Δ in various SC cuprate compounds. We show that it is a very good candidate for the resonance observed in Raman scattering below the 2 Δ peak in the A1 g symmetry. Since the η mode sits in the S =0 channel, it may be observable via Raman, x-ray, or electron energy loss spectroscopy probes.

  9. Observational evidence of Z and L-O mode waves as the origin of auroral kilometric radiation from the Jikiken (EXOS-B) satellite

    NASA Technical Reports Server (NTRS)

    Oya, H.; Morioka, A.

    1983-01-01

    The present investigation has the objective to present new information on the polarization of the auroral kilometric radiation detected by the Jikiken (EXOS-B) satellite. On September 16, 1978, the satellite had been launched into an orbit with altitudes of the initial apogee and perigee of 30,050 km and 250 km, respectively, and an inclination of -31 deg. This orbit provides the conditions for suitable observations of the spectra of auroral kilometric radiation (AKR) in the proximity of the source regions. A study has been conducted of the discovered Z mode waves. These waves are found to be refracted to a nearly perpendicular direction of propagation with respect to the magnetic field vector within a very short distance of the source position. AKR spectra have been observed at positions where the ambient plasma defines a lower edge of the spectra by the cutoff effects of the waves propagating in the local plasma.

  10. Design and fabrication of a 1-DOF drive mode and 2-DOF sense mode micro-gyroscope using SU-8 based UV-LIGA process

    NASA Astrophysics Data System (ADS)

    Verma, Payal; Juneja, Sucheta; Savelyev, Dmitry A.; Khonina, Svetlana N.; Gopal, Ram

    2016-04-01

    This paper presents design and fabrication of a 1-DOF (degree-of-freedom) drive mode and 2-DOF sense mode micro-gyroscope. It is an inherently robust structure and offers a high sense frequency bandwidth. The proposed design utilizes resonance of the1-DOF drive mode oscillator and employs dynamic amplification concept in sense modes to increase the sensitivity while maintaining robustness. The 2-DOF in the sense direction renders the device immune to process imperfections and environmental effects. The design is simulated using FEA software (CoventorWare®). The device is designed considering process compatibility with SU-8 based UV-LIGA process, which is an economical fabrication technique. The complete fabrication process is presented along with SEM images of the fabricated device. The device has 9 µm thick Nickel as the key structural layer with an overall reduced key structure size of 2.2 mm by 2.1 mm.

  11. Experimental results for a 1.5 MW, 110 GHz gyrotron oscillator with reduced mode competition

    SciTech Connect

    Choi, E.M.; Marchewka, C.D.; Mastovsky, I.; Sirigiri, J.R.; Shapiro, M.A.; Temkin, R.J.

    2006-02-15

    A new result from a 110 GHz gyrotron at MIT is reported with an output power of 1.67 MW and an efficiency of 42% when operated at 97 kV and 41 A for 3 {mu}s pulses in the TE{sub 22,6} mode. These results are a major improvement over results obtained with an earlier cavity design, which produced 1.43 MW of power at 37% efficiency. These new results were obtained using a cavity with a reduced output taper angle and a lower ohmic loss when compared with the earlier cavity. The improved operation is shown experimentally to be the result of reduced mode competition from the nearby TE{sub 19,7} mode. The reduced mode competition agrees well with an analysis of the startup scenario based on starting current simulations. The present results should prove useful in planning long pulse and CW versions of the 110 GHz gyrotron.

  12. GFEChutes Lo-Fi

    NASA Technical Reports Server (NTRS)

    Gist, Emily; Turner, Gary; Shelton, Robert; Vautier, Mana; Shaikh, Ashraf

    2013-01-01

    NASA needed to provide a software model of a parachute system for a manned re-entry vehicle. NASA has parachute codes, e.g., the Descent Simulation System (DSS), that date back to the Apollo Program. Since the space shuttle did not rely on parachutes as its primary descent control mechanism, DSS has not been maintained or incorporated into modern simulation architectures such as Osiris and Antares, which are used for new mission simulations. GFEChutes Lo-Fi is an object-oriented implementation of conventional parachute codes designed for use in modern simulation environments. The GFE (Government Furnished Equipment), low-fidelity (Lo-Fi) parachute model (GFEChutes Lo-Fi) is a software package capable of modeling the effects of multiple parachutes, deployed concurrently and/or sequentially, on a vehicle during the subsonic phase of reentry into planetary atmosphere. The term "low-fidelity" distinguishes models that represent the parachutes as simple forces acting on the vehicle, as opposed to independent aerodynamic bodies. GFEChutes Lo-Fi was created from these existing models to be clean, modular, certified as NASA Class C software, and portable, or "plug and play." The GFE Lo-Fi Chutes Model provides basic modeling capability of a sequential series of parachute activities. Actions include deploying the parachute, changing the reefing on the parachute, and cutting away the parachute. Multiple chutes can be deployed at any given time, but all chutes in that case are assumed to behave as individually isolated chutes; there is no modeling of any interactions between deployed chutes. Drag characteristics of a deployed chute are based on a coefficient of drag, the face area of the chute, and the local dynamic pressure only. The orientation of the chute is approximately modeled for purposes of obtaining torques on the vehicle, but the dynamic state of the chute as a separate entity is not integrated - the treatment is simply an approximation. The innovation in GFEChutes

  13. Surface quality of a 1m Zerodur part using an effective grinding mode

    NASA Astrophysics Data System (ADS)

    Tonnellier, X.; Shore, P.; Morantz, P.; Orton, D.

    2008-09-01

    A new ultra precision large optics grinding machine, BoX (R) , has been developed at Cranfield University. This machine is located at the UK's Ultra Precision Surfaces laboratory at the OpTIC Technium, North Wales. This machine offers a rapid and economic solution for grinding large off-axis aspherical and free-form optical components. This paper presents an analysis of surface and subsurface damage assessments of Zerodur(R) ground using diamond resin bonded grinding wheels. Zerodur(R) was tested as it is one of the materials currently under study for making extremely large telescope (ELT) segmented mirrors such as in the E-ELT project. The grinding experiments have been conducted on the BoX(R) grinding machine using wheels with grit sizes of 76 μm, 46 µm and 25 μm. The highest material removal rate (187.5 mm3/s) used ensures that a 1 metre diameter optic can be ground in less than 10 hours. The surface roughness and surface profile were measured using a Form Talysurf. The subsurface damage was revealed using a sub aperture polishing process in combination with an etching technique on small parts. These results are compared with the targeted form accuracy of 1 μm p-v over a 1 metre part, surface roughness of 50-150 nm RMS and subsurface damage in the range of 2-5 μm. This process stage was validated on a 1 metre hexagonal Zerodur(R) part.

  14. First observation of a (1,0) mode frequency shift of an electron plasma at antiproton beam injection.

    PubMed

    Kuroda, N; Mohri, A; Torii, H A; Nagata, Y; Shibata, M

    2014-07-11

    The frequency shift of the center-of-mass oscillation, known as the (1,0) mode, of a trapped electron plasma and, furthermore, its time evolution were observed during the cooling of an injected antiproton beam for the first time. Here, antiprotons mixed with the electrons did not follow faster electron oscillations but contributed to the modification of the effective potential. The time evolution of the plasma temperature, deduced from the frequency shift of the excited (3,0) mode, suggested that there was an abnormal energy deposition of the antiproton beam in the electron plasma before thermalization. PMID:25062195

  15. High-power self-similar amplification seeded by a 1 GHz harmonically mode-locked Yb-fiber laser

    NASA Astrophysics Data System (ADS)

    Luo, Daping; Li, Wenxue; Liu, Yang; Wang, Chao; Zhu, Zhiwei; Zhang, Wenchao; Zeng, Heping

    2016-08-01

    We demonstrate 1 GHz, 75 W, 65 fs pulse generation through chirped-pulse and self-similar amplification of a second-harmonic mode-locked Yb fiber oscillator. To confirm the experimental results of a chirped-pulse pre-amplifier, a theoretically calculative model is designed to simulate gain narrowing in the amplification. Specifically, the Kelly sidebands generated by a seed laser experience similar evolution under both conditions. The grism-based self-similar amplifier together with a high-efficiency grating compressor contribute to high-power ultrashort pulses whose spectra are efficiently broadened to a maximum 10 dB bandwidth of 56 nm with a center wavelength of 1032.2 nm owing to self-phase modulation in a gain fiber.

  16. Astrometric Study of Lo 1339

    NASA Astrophysics Data System (ADS)

    Wiramihardja, S. D.; Arifyanto, M. I.; Sugianto, Y.; Kunjaya, C.

    2010-10-01

    We presented a preliminary result of astrometric study of galactic cluster Lo 1339 using proper motion data from UCAC2 catalog. We applied the maximum likelihood method to determine cluster membership by using the proper motion data. The Padova isochrones lines with solar metallicity were fitted upon the Color Magnitude Diagram in near-infrared to derive physical parameters of the cluster, where we obtained the age of cluster log t = 8.4+/-0.2, the distance of 1284+/-140 pc, and the absorption AJ = 0.26+/-0.13 mag with cluster diameter of 4.9+/-0.5 pc.

  17. High resolution spectroscopy of jet cooled phenyl radical: The ν1 and ν2 a1 symmetry C-H stretching modes

    NASA Astrophysics Data System (ADS)

    Chang, Chih-Hsuan; Nesbitt, David J.

    2016-07-01

    A series of CH stretch modes in phenyl radical (C6H5) has been investigated via high resolution infrared spectroscopy at sub-Doppler resolution (˜60 MHz) in a supersonic discharge slit jet expansion. Two fundamental vibrations of a1 symmetry, ν1 and ν2, are observed and rotationally analyzed for the first time, corresponding to in-phase and out-of-phase symmetric CH stretch excitation at the ortho/meta/para and ortho/para C atoms with respect to the radical center. The ν1 and ν2 band origins are determined to be 3073.968 50(8) cm-1 and 3062.264 80(7) cm-1, respectively, which both agree within 5 cm-1 with theoretical anharmonic scaling predictions based on density functional B3LYP/6-311g++(3df,3dp) calculations. Integrated band strengths for each of the CH stretch bands are analyzed, with the relative intensities agreeing remarkably well with theoretical predictions. Frequency comparison with previous low resolution Ar-matrix spectroscopy [A. V. Friderichsen et al., J. Am. Chem. Soc. 123, 1977 (2001)] reveals a nearly uniform Δν ≈ + 10-12 cm-1 blue shift between gas phase and Ar matrix values for ν1 and ν2. This differs substantially from the much smaller red shift (Δν ≈ - 1 cm-1) reported for the ν19 mode, and suggests a simple physical model in terms of vibrational mode symmetry and crowding due to the matrix environment. Finally, the infrared phenyl spectra are well described by a simple asymmetric rigid rotor Hamiltonian and show no evidence for spectral congestion due to intramolecular vibrational coupling, which bodes well for high resolution studies of other ring radicals and polycyclic aromatic hydrocarbons. In summary, the combination of slit jet discharge methods with high resolution infrared lasers enables spectroscopic investigation of even highly reactive combustion and interstellar radical intermediates under gas phase, jet-cooled (Trot ≈ 11 K) conditions.

  18. High resolution spectroscopy of jet cooled phenyl radical: The ν1 and ν2 a1 symmetry C-H stretching modes.

    PubMed

    Chang, Chih-Hsuan; Nesbitt, David J

    2016-07-28

    A series of CH stretch modes in phenyl radical (C6H5) has been investigated via high resolution infrared spectroscopy at sub-Doppler resolution (∼60 MHz) in a supersonic discharge slit jet expansion. Two fundamental vibrations of a1 symmetry, ν1 and ν2, are observed and rotationally analyzed for the first time, corresponding to in-phase and out-of-phase symmetric CH stretch excitation at the ortho/meta/para and ortho/para C atoms with respect to the radical center. The ν1 and ν2 band origins are determined to be 3073.968 50(8) cm(-1) and 3062.264 80(7) cm(-1), respectively, which both agree within 5 cm(-1) with theoretical anharmonic scaling predictions based on density functional B3LYP/6-311g++(3df,3dp) calculations. Integrated band strengths for each of the CH stretch bands are analyzed, with the relative intensities agreeing remarkably well with theoretical predictions. Frequency comparison with previous low resolution Ar-matrix spectroscopy [A. V. Friderichsen et al., J. Am. Chem. Soc. 123, 1977 (2001)] reveals a nearly uniform Δν ≈ + 10-12 cm(-1) blue shift between gas phase and Ar matrix values for ν1 and ν2. This differs substantially from the much smaller red shift (Δν ≈ - 1 cm(-1)) reported for the ν19 mode, and suggests a simple physical model in terms of vibrational mode symmetry and crowding due to the matrix environment. Finally, the infrared phenyl spectra are well described by a simple asymmetric rigid rotor Hamiltonian and show no evidence for spectral congestion due to intramolecular vibrational coupling, which bodes well for high resolution studies of other ring radicals and polycyclic aromatic hydrocarbons. In summary, the combination of slit jet discharge methods with high resolution infrared lasers enables spectroscopic investigation of even highly reactive combustion and interstellar radical intermediates under gas phase, jet-cooled (Trot ≈ 11 K) conditions. PMID:27475358

  19. CEO stabilized frequency comb from a 1-μm Kerr-lens mode-locked bulk Yb:CYA laser.

    PubMed

    Yu, Zijiao; Han, Hainian; Xie, Yang; Peng, Yingnan; Xu, Xiaodong; Wei, Zhiyi

    2016-02-01

    We report the first Kerr-lens mode-locked (KLM) bulk frequency comb in the 1-μm spectral regime. The fundamental KLM Yb:CYA laser is pumped by a low-noise, high-bright 976-nm fiber laser and typically provides 250-mW output power and 57-fs pulse duration. Only 58-mW output pulses were launched into a 1.3-m photonic crystal fiber (PCF) for one octave-spanning supercontinuum generation. Using a simplified collinear f-2f interferometer, the free-running carrier-envelope offset (CEO) frequency was measured to be 42-dB signal-to-noise ratio (SNR) for a 100-kHz resolution and 9.6-kHz full width at half maximum (FWHM) under a 100-Hz resolution. A long-term CEO control at 23 MHz was ultimately realized by feeding the phase error signal to the pump power of the oscillator. The integrated phase noise (IPN) of the locked CEO was measured to be 316 mrad with an integrated range from 1 Hz to 10 MHz. The standard deviation and Allan deviation for more than 4-hour recording are 1.6 mHz and 5.6 × 10(-18) (for 1-s gate time), respectively. This is, to the best of our knowledge, the best stability achieved among the 1-μm solid-state frequency combs. PMID:26906875

  20. LoWMob: Intra-PAN Mobility Support Schemes for 6LoWPAN.

    PubMed

    Bag, Gargi; Raza, Muhammad Taqi; Kim, Ki-Hyung; Yoo, Seung-Wha

    2009-01-01

    Mobility in 6LoWPAN (IPv6 over Low Power Personal Area Networks) is being utilized in realizing many applications where sensor nodes, while moving, sense and transmit the gathered data to a monitoring server. By employing IEEE802.15.4 as a baseline for the link layer technology, 6LoWPAN implies low data rate and low power consumption with periodic sleep and wakeups for sensor nodes, without requiring them to incorporate complex hardware. Also enabling sensor nodes with IPv6 ensures that the sensor data can be accessed anytime and anywhere from the world. Several existing mobility-related schemes like HMIPv6, MIPv6, HAWAII, and Cellular IP require active participation of mobile nodes in the mobility signaling, thus leading to the mobility-related changes in the protocol stack of mobile nodes. In this paper, we present LoWMob, which is a network-based mobility scheme for mobile 6LoWPAN nodes in which the mobility of 6LoWPAN nodes is handled at the network-side. LoWMob ensures multi-hop communication between gateways and mobile nodes with the help of the static nodes within a 6LoWPAN. In order to reduce the signaling overhead of static nodes for supporting mobile nodes, LoWMob proposes a mobility support packet format at the adaptation layer of 6LoWPAN. Also we present a distributed version of LoWMob, named as DLoWMob (or Distributed LoWMob), which employs Mobility Support Points (MSPs) to distribute the traffic concentration at the gateways and to optimize the multi-hop routing path between source and destination nodes in a 6LoWPAN. Moreover, we have also discussed the security considerations for our proposed mobility schemes. The performance of our proposed schemes is evaluated in terms of mobility signaling costs, end-to-end delay, and packet success ratio. PMID:22346730

  1. Building an LO source at 1036 GHz for a receiver

    NASA Technical Reports Server (NTRS)

    Erickson, Neal R.

    1995-01-01

    The goal of the UMass work on this grant was to build an LO source at 1036 GHz for a receiver which was to be built at JPL. The 1 THz source will consist of a high power Gunn oscillator at 86 GHz followed by a cascaded pair of planar diode doublers and finally a whisker contacted tripler. All multipliers will use single mode waveguide mounts. This use of single mode waveguide even for the final mount is a departure from the original plan, and reflects the progress that has been made in fabricating small structures. The advantages to the use of waveguide over a quasi-optical approach are that the complete system is much more compact, and much easier to use.

  2. Specialized and independent processing of orientation and shape in visual field maps LO1 and LO2.

    PubMed

    Silson, Edward H; McKeefry, Declan J; Rodgers, Jessica; Gouws, Andre D; Hymers, Mark; Morland, Antony B

    2013-03-01

    We identified human visual field maps, LO1 and LO2, in object-selective lateral occipital cortex. Using transcranial magnetic stimulation (TMS), we assessed the functions of these maps in the perception of orientation and shape. TMS of LO1 disrupted orientation, but not shape, discrimination, whereas TMS of LO2 disrupted shape, but not orientation, discrimination. This double dissociation suggests that specialized and independent processing of different visual attributes occurs in LO1 and LO2. PMID:23377127

  3. PRECISION POINTING OF IBEX-Lo OBSERVATIONS

    SciTech Connect

    Hlond, M.; Bzowski, M.; Moebius, E.; Kucharek, H.; Heirtzler, D.; Schwadron, N. A.; Neill, M. E. O'; Clark, G.; Crew, G. B.; Fuselier, S.; McComas, D. J. E-mail: eberhard.moebius@unh.edu E-mail: stephen.a.fuselier@linco.com E-mail: DMcComas@swri.edu

    2012-02-01

    Post-launch boresight of the IBEX-Lo instrument on board the Interstellar Boundary Explorer (IBEX) is determined based on IBEX-Lo Star Sensor observations. Accurate information on the boresight of the neutral gas camera is essential for precise determination of interstellar gas flow parameters. Utilizing spin-phase information from the spacecraft attitude control system (ACS), positions of stars observed by the Star Sensor during two years of IBEX measurements were analyzed and compared with positions obtained from a star catalog. No statistically significant differences were observed beyond those expected from the pre-launch uncertainty in the Star Sensor mounting. Based on the star observations and their positions in the spacecraft reference system, pointing of the IBEX satellite spin axis was determined and compared with the pointing obtained from the ACS. Again, no statistically significant deviations were observed. We conclude that no systematic correction for boresight geometry is needed in the analysis of IBEX-Lo observations to determine neutral interstellar gas flow properties. A stack-up of uncertainties in attitude knowledge shows that the instantaneous IBEX-Lo pointing is determined to within {approx}0.{sup 0}1 in both spin angle and elevation using either the Star Sensor or the ACS. Further, the Star Sensor can be used to independently determine the spacecraft spin axis. Thus, Star Sensor data can be used reliably to correct the spin phase when the Star Tracker (used by the ACS) is disabled by bright objects in its field of view. The Star Sensor can also determine the spin axis during most orbits and thus provides redundancy for the Star Tracker.

  4. Precision Pointing of IBEX-Lo Observations

    NASA Astrophysics Data System (ADS)

    Hłond, M.; Bzowski, M.; Möbius, E.; Kucharek, H.; Heirtzler, D.; Schwadron, N. A.; O'Neill, M. E.; Clark, G.; Crew, G. B.; Fuselier, S.; McComas, D. J.

    2012-02-01

    Post-launch boresight of the IBEX-Lo instrument on board the Interstellar Boundary Explorer (IBEX) is determined based on IBEX-Lo Star Sensor observations. Accurate information on the boresight of the neutral gas camera is essential for precise determination of interstellar gas flow parameters. Utilizing spin-phase information from the spacecraft attitude control system (ACS), positions of stars observed by the Star Sensor during two years of IBEX measurements were analyzed and compared with positions obtained from a star catalog. No statistically significant differences were observed beyond those expected from the pre-launch uncertainty in the Star Sensor mounting. Based on the star observations and their positions in the spacecraft reference system, pointing of the IBEX satellite spin axis was determined and compared with the pointing obtained from the ACS. Again, no statistically significant deviations were observed. We conclude that no systematic correction for boresight geometry is needed in the analysis of IBEX-Lo observations to determine neutral interstellar gas flow properties. A stack-up of uncertainties in attitude knowledge shows that the instantaneous IBEX-Lo pointing is determined to within ~0fdg1 in both spin angle and elevation using either the Star Sensor or the ACS. Further, the Star Sensor can be used to independently determine the spacecraft spin axis. Thus, Star Sensor data can be used reliably to correct the spin phase when the Star Tracker (used by the ACS) is disabled by bright objects in its field of view. The Star Sensor can also determine the spin axis during most orbits and thus provides redundancy for the Star Tracker.

  5. Lo Gnomone Clementino Astronomia Meridiana in Basilica

    NASA Astrophysics Data System (ADS)

    Sigismondi, Costantino

    2014-05-01

    Costruito per chiara volontà del papa 70 anni dopo il caso Galileo, lo Gnomone Clementino è un grande telescopio solare che non fa uso di lenti a 92 anni dall’invenzione del cannocchiale. Queste due caratteristiche basterebbero da sole a giustificare l’interesse verso questo strumento. L’astronomia meridiana è alla base dell’astrometria e dell’astrofisica moderna. Lo Gnomone Clementino sta oggi all’astronomia, come il veliero “Amerigo Vespucci” sta alla Marina Italiana. E’ possibile svolgere ogni genere di osservazione e studio su questo strumento, e dal 2002 vi tengo lezioni teorico-pratiche del corso di Storia dell’Astronomia e La Terra nel Sistema Solare della Sapienza, Università di Roma, Facoltà di Lettere e Filosofia. Questo testo aggiunge alcuni tasselli alla ricerca storica sulla meridiana, appoggiandosi, com’è naturale, sulle spalle di giganti che mi hanno preceduto in questi studi. In particolare la misura dell’azimut della meridiana, ed il suo inquadramento tra gli strumenti simili ed alcuni studi di astrometria sui dati del 1701-1703 di Bianchini, che sono apparsi fin’ora soltanto su riviste specializzate ed in Inglese vengono qui proposti in Italiano e semplificati, per valorizzare sempre più questa straordinaria opera d’arte e di scienza.

  6. The reduction of the LO number for heterodyne coherent detection.

    PubMed

    Li, Xinying; Yu, Jianjun; Chi, Nan; Dong, Ze; Zhang, Junwen; Yu, Jianguo

    2012-12-31

    Relative to homodyne coherent detection, heterodyne coherent detection has simple architecture because no 90° hybrid and only half number of photodiodes and analog-to-digital convertor (ADC) chips are required. We experimentally demonstrate that the architecture of heterodyne coherent receivers can be further simplified. When the frequency offset is one half of the channel frequency spacing, one local oscillator (LO) laser can be used for two neighboring wavelength-division-multiplexing (WDM) channels, and therefore the number of LO lasers can be reduced into half compared to homodyne detection. We experimentally demonstrate simplified heterodyne coherent detection of 4 × 196.8-Gb/s polarization-division-multiplexing carrier-suppressed return-to-zero quadrature-phase-shift-keying (PDM-CSRZ-QPSK) modulation after transmission over 1040-km single-mode fiber (SMF)-28 on a 50-GHz grid with bit-error ratio (BER) smaller than pre-forward-error-correction (pre-FEC) limit of 3.8 × 10(-3). To our best knowledge, 196.8 Gb/s is the highest bit rate per channel for heterodyne coherent WDM transmission system. An arrayed waveguide grating (AWG) instead of wavelength selective switch (WSS) is used at the transmitter to spectrally shape and multiplex the WDM signal. We also experimentally demonstrate that heterodyne detection causes 3-dB optical signal-to-noise ratio (OSNR) penalty at the BER of 3.8 × 10(-3) for a certain single channel compared to homodyne detection. PMID:23388788

  7. Starspots on LO Pegasi, 2006-2015

    NASA Astrophysics Data System (ADS)

    Harmon, Robert O.; Chalmers, Mark; Geda, Robel; Henry, Brandi; Sliupas, Viesulas

    2016-01-01

    LO Pegasi is a rapidly rotating (P = 10.154 hr) young solar analog (spectral class K5-7V) variable star of BY Dra type that exhibits dark starspots on its surface that modulate its brightness as they are carried into and out of view by the star's rotation. Surface maps of the spot distribution were produced based on BVRI photometry obtained at Perkins Observatory from 2006-2015. The maps were generated from the light curves via a non-linear inversion algorithm that uses the differences in the limb darkening through different filter passbands to improve the latitude resolution of the maps. We present an analysis of variations in the size of a polar spot suggested by changes in the average brightness and the amplitude of the rotational modulation from year to year.

  8. Starspots on LO Pegasi, 2006-2014

    NASA Astrophysics Data System (ADS)

    Harmon, Robert O.; Berry, Dominique; Chalmers, Mark; Denison, Josh; Stevens, Don; Yuhas, Kaylee

    2015-01-01

    BVRI light curves of LO Pegasi obtained at Perkins Observatory (Ohio Wesleyan University) from 2006-2014 were used to study the evolution of starspots on its surface over that interval. We present surface maps obtained via a constrained non-linear inversion algorithm that uses variations in limb darkening as seen through different filters to improve the latitude resolution of the reconstructions. In addition, a detailed period analysis of the entire data set using the ANOVA method was performed to search for variations associated with differential rotation. No evidence of period change was found, as the periods for each year were equal to within their uncertainties. For the data set as a whole, the period of rotation was determined to be 10.1538 ± 0.0009 hr, in agreement with previously published results.

  9. Stellar Surface Imaging of LO Pegasi

    NASA Astrophysics Data System (ADS)

    Decker, Rachel; Moore, Conrad; Harmon, Robert

    2008-10-01

    We present images of dark starspots on the surface of the K8 main-sequence star LO Pegasi. CCD camera images of the star and surrounding field were acquired through B, V, R and I filters at Perkins Observatory in Delaware, OH on clear nights in June and July, 2008. The images were dark-subtracted and flat-fielded and then aperture photometry was performed to yield light curves through each of the four filters. These light curves were then simultaneously inverted via an algorithm devised by one of us (Harmon) so as to yield images of the spots based on the rotational modulation they produced in the light curves. The use of multiple filters significantly improves the latitude resolution of the reconstructions. Comparison of our results with results from 2006 and 2007 shows that the spot structure was more complex in 2008 than in the prior years.

  10. Kinetic description of an electron--LO-phonon system with finite phonon lifetime

    SciTech Connect

    Nguyen, V.T.; Mahler, G. )

    1992-02-15

    We study the cooling of an electron plasma from a kinetic point of view. For this purpose, a quantum theory of fluctuations is applied to derive the kinetic equations for an electron--LO-phonon system from various model Hamiltonians. A polarization approximation is provided that goes beyond perturbation theory of the electron-phonon interaction. The description of electron-phonon energy exchange is shown to be impossible with the interacting Hamiltonian in Froehlich's one-phonon form unless dissipation of the bare LO phonon is included. For a Hamiltonian including effects of the scattering of LO phonons by acoustic phonons, kinetic equations are derived. The equation for LO phonons is shown to describe the collective excitations with finite lifetime, in the limiting case of weak damping of the plasmon-phonon coupled modes. A reduction of the cooling rate similar to the hot-phonon'' effect is shown to occur for the case of weak coupling without assuming a steady state of the LO phonons. Finally, an electron-phonon interaction Hamiltonian in two-phonon form is considered and it is shown that electron-phonon energy exchange may be described in the polarization approximation without introducing a finite phonon lifetime.

  11. Deep analysis of Raman spectra of ZnO:Mo and ZnO:In sprayed thin films along with LO and TA+LO bands investigation

    NASA Astrophysics Data System (ADS)

    Souissi, A.; Amlouk, M.; Khemakhem, H.; Guermazi, S.

    2016-04-01

    ZnO and Mo, In doped ZnO thin films with the molar ratios (Mo/Zn) and (In/Zn) were dosed at 1%, 2% and 3%, respectively. These films were deposited on amorphous SiO2 substrate at 460 °C by the spray-pyrolysis process. A useful and concise reminder of the spatial resolutions of Raman spectroscopy was presented. The vibrational responses of these films at high doping exhibited strong fluctuations that were resolved by successive digital processing, choice of the optimal profile of the baseline, suppression of fluorescence and/or photoluminescence, and noise reduction. These treated spectra have allowed to identify possible multi-modes in highly doped studied samples and revealed the presence of LO and TA+LO broad bands, whose second was at cascade and could be explored in optoelectronic and sensitive systems.

  12. Starspots on LO Pegasi, 2006-2013

    NASA Astrophysics Data System (ADS)

    Harmon, Robert O.; Cole, B.; Denison, J.; Gray, K.

    2014-01-01

    LO Pegasi is a K8 main-sequence variable of BY Dra type, exhibiting dark starspots on its surface which modulate its brightness as they are carried into and out of view by the star's rotation. We present the results of BVRI photometry obtained at Perkins Observatory in Delaware, OH from 2006-2013. The light curve shape and by implication the spot configuration is stable on a time scale of several months, but shows substantial year-to-year variations. In particular, the V modulation was a maximum of approximately 0.15 mag in June-July 2011, and a minimum of approximately 0.04 mag in 2012 and 2013. In addition, the mean brightness was lowest in 2012, suggesting the growth of a large spot on the visible rotation pole, which would simultaneously account for the small modulation and lowered mean brightness. In 2013, the mean brightness increased by about 0.05 mag compared to 2012, suggesting that the polar spot is shrinking in size.

  13. Advances in LO2 Propellant Conditioning

    NASA Technical Reports Server (NTRS)

    Mehta, Gopal; Orth, Michael; Stone, William; Perry, Gretchen; Holt, Kimberly; Suter, John

    1994-01-01

    This paper describes the cryogenic testing and analysis that has recently been completed as part of a multi-year effort to develop a new, more robust and operable LO2 propellant conditioning system. Phase 1 of the program consisted of feasibility demonstrations ot four novel propellant conditioning concepts. A no-bleed, passive propellant conditioning option was shown for the first time to successfully provide desired propellant inlet conditions. The benefits of passive conditioning are reduced operations costs, decreased hardware costs, enhanced operability and increased reliability on future expendable launch vehicles In Phase 2 of the test program, effects of major design parameters were studied and design correlation for future vehicle design were developed. Simultaneously, analytical models were developed and validated. Over 100 tests were conducted with a full-scale feedline using LN2 as the test fluid. A circulation pump provided a range of pressure and flow conditions. The test results showed that the passive propellant conditioning system is insensitive to variations in many of the parameters. The test program provides the validation necessary to incorporate the passive conditioning system into the baseline of future vehicles. Modeling of these systems using computational fluid dynamics seems highly promising.

  14. Carbon deposition characteristics of LO2/HC propellants

    NASA Technical Reports Server (NTRS)

    Hernandez, Rosemary; Mercer, Steve D.

    1987-01-01

    The generation and deposition of carbon have been studied using subscale hardware with LO2/RP-1, LO2/propane, and LO2/methane at low mixture ratio conditions. The deposition of carbon on the turbine simulator tubes was evaluated at mixture ratios of 0.20 to 0.60, and at chamber pressures from 720 to 1650 psia. The carbon-deposition rate is a strong function of mixture ratio and a weak function of chamber pressure. There is a mixture ratio that will minimize deposition for LO2/RP-1; a threshold mixture ratio for LO2/propane; and no deposition for LO2/methane at any mixture ratio tested. The turbine drive operating limits were defined for each fuel tested.

  15. Selenoprotein X Gene Knockdown Aggravated H2O2-Induced Apoptosis in Liver LO2 Cells.

    PubMed

    Tang, Jiayong; Cao, Lei; Li, Qiang; Wang, Longqiong; Jia, Gang; Liu, Guangmang; Chen, Xiaoling; Cai, Jingyi; Shang, Haiying; Zhao, Hua

    2016-09-01

    To determine the roles of selenoprotein X gene (Selx) in protecting liver cells against oxidative damage, the influences of Selx knockdown on H2O2-induced apoptosis in human normal hepatocyte (LO2) cells were studied. pSilencer 3.1 was used to develop knockdown vector targeting the 3'-UTR of human Selx. The Selx knockdown and control cells were further exposed to H2O2, and cell viability, cell apoptosis rate, and the expression levels of mRNA and protein of apoptosis-related genes were detected. The results showed that vector targeting the 3'-UTR of Selx successfully silenced mRNA or protein expression of SelX in LO2 cells. Selx knockdown resulted in decreased cell viability, increased percentage of early apoptotic cells, decreased Bcl2A1 and Bcl-2 expression, and increased phosphorylation of P38 in LO2 cells. When Selx knockdown LO2 cells were exposed to H2O2, characteristics of H2O2-induced cell dysfunctions were further exacerbated. Taken together, our findings suggested that SelX played important roles in protecting LO2 cells against oxidative damage and reducing H2O2-induced apoptosis in liver cells. PMID:26899321

  16. Como Lo Hago Yo: Mielomeningocele En Bolivia

    PubMed Central

    Dabdoub, Carlos F.; Dabdoub, Carlos B.; Villavicencio, Ramiro; Quevedo, Germán

    2014-01-01

    Introducción: Las malformaciones del tubo neural (MTN) representan la segunda causa más frecuente de anomalías congénitas, luego de las cardiopatías. En este grupo se destaca el mielomeningocele (MMC) por su mayor incidencia, y por ser la más incapacitante y la más compleja entre todas las demás malformaciones del sistema nervioso c`entral (SNC). En Bolivia, como en muchos países de Sudamérica, los bajos niveles socio-culturales y la debilidad en el sistema sanitario, hacen que su incidencia y su morbilidad, sean mayores que en las naciones más desarrolladas. Material y Métodos: Se realizó un estudio retrospectivo y descriptivo de 70 casos de MMC, atendidos por un equipo multidisciplinario en el Hospital Universitario Japonés (HUJ) de Santa Cruz de la Sierra, entre 2008-2011. De ellos, 60 fueron intervenidos quirúrgicamente. Resultados: Se realizaron controles prenatales sólo en 27 mujeres (38.6%), diagnosticándose una disrafia espinal en apenas dos casos (7.4%). La edad de ingreso del MMC en su mayoría fue después de las 24 horas (65.6%), predominando su localización en la región lumbosacra (64.3%). De ellos, 67.2% eran abiertos, presentando un 32.9% un daño neurológico motor parcial mientras que 47.1% tenían paraplejia por debajo de la lesión. De los 70 casos, tres (4.3%) no fueron intervenidos, por presentar defectos congénitos severos o estado general grave. Las principales complicaciones posoperatorias inmediatas fueron: dehiscencia de sutura y/o infección de la herida (16.6%), fístula de líquido cefalorraquídeo (LCR) (10%) e infección del SNC (11.7%). La mortalidad general y postoperatoria fue de 7.1% y 3.3%, respectivamente. Al mes de vida presentaban hidrocefalia un 80% de los pacientes operados, colocándose una derivación ventriculoperitoneal (DVP) de presión media. De 9 pacientes que tuvieron un acompanamiento de dos o más años, seis presentaron una médula anclada, que fueron intervenidas quirúrgicamente. Conclusi

  17. Lo/Ld phase coexistence modulation induced by GM1.

    PubMed

    Puff, Nicolas; Watanabe, Chiho; Seigneuret, Michel; Angelova, Miglena I; Staneva, Galya

    2014-08-01

    Lipid rafts are assumed to undergo biologically important size-modulations from nanorafts to microrafts. Due to the complexity of cellular membranes, model systems become important tools, especially for the investigation of the factors affecting "raft-like" Lo domain size and the search for Lo nanodomains as precursors in Lo microdomain formation. Because lipid compositional change is the primary mechanism by which a cell can alter membrane phase behavior, we studied the effect of the ganglioside GM1 concentration on the Lo/Ld lateral phase separation in PC/SM/Chol/GM1 bilayers. GM1 above 1mol % abolishes the formation of the micrometer-scale Lo domains observed in GUVs. However, the apparently homogeneous phase observed in optical microscopy corresponds in fact, within a certain temperature range, to a Lo/Ld lateral phase separation taking place below the optical resolution. This nanoscale phase separation is revealed by fluorescence spectroscopy, including C12NBD-PC self-quenching and Laurdan GP measurements, and is supported by Gaussian spectral decomposition analysis. The temperature of formation of nanoscale Lo phase domains over an Ld phase is determined, and is shifted to higher values when the GM1 content increases. A "morphological" phase diagram could be made, and it displays three regions corresponding respectively to Lo/Ld micrometric phase separation, Lo/Ld nanometric phase separation, and a homogeneous Ld phase. We therefore show that a lipid only-based mechanism is able to control the existence and the sizes of phase-separated membrane domains. GM1 could act on the line tension, "arresting" domain growth and thereby stabilizing Lo nanodomains. PMID:24835016

  18. The Sublime Corpse in Gertrudis Gomez de Avellaneda's Women's Journal "Album Cubano de lo Bueno y lo Bello" (1860)

    ERIC Educational Resources Information Center

    LaGreca, Nancy

    2009-01-01

    This article examines Gertrudis Gomez de Avellaneda's choice to include articles depicting the advanced decay of cadavers, which are simultaneously horrible and awesome, in her women's periodical "Album Cubano de lo Bueno y lo Bello". Background on Avellaneda's biography, women's print culture, and theories of the sublime provide a frame for the…

  19. 77 FR 50185 - LoCorr Fund Management, LLC and LoCorr Investment Trust; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-20

    ... standard. 3. Applicants assert that the shareholders expect the Adviser and the Board to select the... shareholder approval. Applicants: LoCorr Fund Management, LLC (``LFM'' or the ``Adviser'') and LoCorr... materially amend Subadvisory Agreements without obtaining shareholder approval. The requested relief will...

  20. Evaluations of University of Wisconsin Silicon Carbide Temperature Monitors 300 LO and 400 LO B

    SciTech Connect

    K. L. Davis; J. L. Rempe; D. L. Knudson; B. M. Chase; T. C. Unruh

    2011-12-01

    Silicon carbide (SiC) temperature monitors 05R4-02-A KG1403 (300 LO) and 05R4-01-A KG1415 (400 LO B) were evaluated at the High Temperature Test Lab (HTTL) to determine their peak irradiation temperatures. HTTL measurements indicate that the peak irradiation temperature for the 300 LO monitor was 295 {+-} 20 C and the peak irradiation temperature for the 400 LO B monitor was 294 {+-} 25 C. Two silicon carbide (SiC) temperature monitors irradiated in the Advanced Test Reactor (ATR) were evaluated at the High Temperature Test Lab (HTTL) to determine their peak temperature during irradiation. These monitors were irradiated as part of the University of Wisconsin Pilot Project with a target dose of 3 dpa. Temperature monitors were fabricated from high density (3.203 g/cm3) SiC manufactured by Rohm Haas with a nominal size of 12.5 mm x 1.0 mm x 0.75 mm (see Attachment A). Table 1 provides identification for each monitor with an expected peak irradiation temperature range based on preliminary thermal analysis (see Attachment B). Post irradiation calculations are planned to reduce uncertainties in these calculated temperatures. Since the early 1960s, SiC has been used as a post-irradiation temperature monitor. As noted in Reference 2, several researchers have observed that neutron irradiation induced lattice expansion of SiC annealed out when the post-irradiation annealing temperature exceeds the peak irradiation temperature. As noted in Reference 3, INL uses resistivity measurements to infer peak irradiation temperature from SiC monitors. Figure 1 depicts the equipment at the HTTL used to evaluate the SiC monitors. The SiC monitors are heated in the annealing furnace using isochronal temperature steps that, depending on customer needs, can range from 50 to 800 C. This furnace is located under a ventilation hood within the stainless steel enclosure. The ventilation system is activated during heating so that any released vapors are vented through this system. Annealing

  1. Nonlinear Analysis of the Space Shuttle Superlightweight LO2 Tank. Part 1; Bahavior Under Booster Ascent Loads

    NASA Technical Reports Server (NTRS)

    Young, Richard D.; Nemeth, Michael P.; Collins, Timothy J.; Starnes, James H., Jr.

    1998-01-01

    Results of linear bifurcation and nonlinear analyses of the Space Shuttle superlightweight (SLWT) external liquid-oxygen (LO2) tank for an important early booster ascent loading condition are presented. These results for thin-walled linear elastic shells that are subjected to combined mechanical and thermal loads illustrate an important type of response mode that may be encountered in the design of other liquid-fuel launch vehicles. Linear bifurcation analyses are presented that predict several nearly equal eigenvalues that correspond to local buckling modes in the forward ogive section of the LO2 tank. In contrast, the nonlinear response phenomenon is shown to consist of short-wavelength bending deformations in the forward ogive and barrel sections of the LO2 tank that growing amplitude in a stable manner increasing load. Imperfection sensitivity analyses are presented that show that the presence of several nearly equal eigenvalues does not lead to a premature general instability mode for the forward ogive section. For the linear bifurcation and nonlinear analyses, the results show that accurate predictions of the response of the shield generally require a large-scale, high-fidelity finite-element model. Results are also presented that show that the SLWT LO2 tank can support loads in excess of approximately 2.6 times the values of the operational loads considered.

  2. 12. DETAIL VIEW OF WEST ABUTMENT AT Lo, SHOWING BRIDGE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. DETAIL VIEW OF WEST ABUTMENT AT Lo, SHOWING BRIDGE SEAT, TIMBER PILES, STEEL SILL AND BACKWALL/WlNGWALL BOARDS, LOOKING NORTH - Cottonville Bridge, County Road D-61 at Farmer's Creek, Maquoketa, Jackson County, IA

  3. Low-z LoBAL QSOs: orientation or evolution?

    NASA Astrophysics Data System (ADS)

    Lazarova, M.

    2015-09-01

    Low-ionization Broad Absorption Line QSOs (LoBALs) are redder type-1 QSOs characterized by broad, blue-shifted absorptions of Mg II, indicating gas outflows at velocities up to 0.2c. There is still much debate regarding the nature of these objects. In the orientation paradigm, LoBALs are present in all QSOs, but can only be observed along limited lines of sight that skim the obscuring torus. Conversely, in the evolution paradigm LoBALS have been interpreted as being a short phase in the early stages of the QSO lifecycle, when QSO-driven winds are expelling gas and dust from the central regions. To explore the suggestion by previous work that LoBALS are more likely to be observed in mergers and recently fueled QSOs, we conducted a morphological analysis of a volume-limited sample of 22 SDSS-selected LoBALs at 0.5 < z < 0.6 using HST/WFC3. We find signs of recent or ongoing tidal interaction in 2/3 of the host galaxies, and detailed surface brightness analysis with GALFIT indicates that the vast majority have early-type morphologies. Our results confirm the high rate of mergers in LoBAL hosts and they further show that LoBALs can be observed at any stage of the merger when QSO activity is expected, according to numerical simulations. While the morphologies of these objects may support the evolution paradigm, their SEDs do not suggest they are a population of QSOs statistically different from optically-selected type-1 QSOs. We discuss the two possible explanations for LoBALs implied by our results.

  4. LoFASM's FPGA-based Digital Acquisition System

    NASA Astrophysics Data System (ADS)

    Dartez, Louis P.; Jenet, F.; Creighton, T. D.; Ford, A. J.; Hicks, B.; Hinojosa, J.; Kassim, N. E.; Price, R. H.; Stovall, K.; Ray, P. S.; Taylor, G. B.

    2014-01-01

    The Low Frequency All Sky Monitor (LoFASM) is a distributed array of dipole antennas that are sensitive to radio frequencies from 10 to 88 MHz. LoFASM consists of antennas and front end electronics that were originally developed for the Long Wavelength Array (LWA) by the U.S. Naval Research Lab, the University of New Mexico, Virginia Tech, and the Jet Propulsion Laboratory. LoFASM, funded by the U.S. Department of Defense, will initially consist of 4 stations, each consisting of 12 dual-polarization dipole antenna stands. The primary science goals of LoFASM will be the detection and study of low-frequency radio transients, a high priority science goal as deemed by the National Research Council's decadal survey. The data acquisition system for the LoFASM antenna array will be using Field Programmable Gate Array (FPGA) technology to implement a real time full Stokes spectrometer and data recorder. This poster presents an overview of the current design and digital architecture of a single station of the LoFASM array as well as the status of the entire project.

  5. Symmetry-adapted tight-binding calculations of the totally symmetric A1 phonons of single-walled carbon nanotubes and their resonant Raman intensity

    NASA Astrophysics Data System (ADS)

    Popov, Valentin N.; Lambin, Philippe

    2007-03-01

    The atomistic calculations of the physical properties of perfect single-walled carbon nanotubes based on the use of the translational symmetry of the nanotubes face increasing computational difficulties for most of the presently synthesized nanotubes with up to a few thousand atoms in the unit cell. This difficulty can be circumvented by use of the helical symmetry of the nanotubes and a two-atom unit cell. We present the results of such symmetry-adapted tight-binding calculations of the totally symmetric A1 phonons (the RBM and the G-band modes) and their resonant Raman intensity for several hundred nanotubes. In particular, we show that (1) the frequencies and the resonant Raman intensity of the RBM and the G-band modes show diameter and chirality dependence and family patterns, (2) the strong electron- A1LO phonon interactions in metallic nanotubes lead to Kohn anomalies at the zone center, (3) the G-band consists of a subband due to A1LO phonons of semiconducting tubes centered at ∼1593 cm -1, a subband of A1TO phonons at ∼1570 cm -1, and a subband of A1LO phonons of metallic tubes at ∼1540 cm -1. The latter prediction confirms previous theoretical results but disagrees with the commonly adopted assignment of the G-band features.

  6. Quadrature Mixer LO Leakage Suppression Through Quadrature DC Bias

    SciTech Connect

    BALDWIN, JESSE G; DUBBERT, DALE F.

    2002-05-01

    A new concept has been developed which allows direct-to-RF conversion of digitally synthesized waveforms. The concept named Quadrature Error Corrected Digital Waveform Synthesis (QECDWS) employs quadrature amplitude and phase predistortion to the complex waveform to reduce the undesirable quadrature image. Another undesirable product of QECDWS-based RF conversion is the Local Oscillator (LO) leakage through the quadrature upconverter (mixer). A common technique for reducing this LO leakage is to apply a quadrature bias to the mixer I and Q inputs. This report analyzes this technique through theory, lab measurement, and data analysis for a candidate quadrature mixer for Synthetic Aperture Radar (SAR) applications.

  7. Low energy neutron deuteron scattering to N3LO

    NASA Astrophysics Data System (ADS)

    Margaryan, Arman; Vanasse, Jared; Springer, Roxanne

    2015-10-01

    We calculate the next-to-next-to-next-to-leading order (N3LO) nd scattering amplitude in the framework of nonrelativistic pionless effective field theory (EFTπ/). This theory is only valid when the typical momentum exchange in the scattering is smaller then the mass of the pion. The power counting parameter for EFTπ/ is the ratio Q/Λπ /, where Q is the typical momentum exchange in the scattering and Λπ / is the EFTπ/ breakdown scale, Λπ / LO. At N3LO new 2-body forces appear, which introduce four new EFTπ/ coefficients. These coefficients are fixed by the 3PJ and 1P1 phase shifts of NN scattering. We find that these terms have an important impact. The results of this calculation at N3LO will be important for understanding spin polarization observables in nd scattering, in particular the longstanding Ay puzzle. This material is based upon work supported by the U.S. Department of Energy Office of Science, Office of Nuclear Physics, under Award Number DE-FG02-05ER41368.

  8. BabeLO--An Extensible Converter of Programming Exercises Formats

    ERIC Educational Resources Information Center

    Queiros, R.; Leal, J. P.

    2013-01-01

    In the last two decades, there was a proliferation of programming exercise formats that hinders interoperability in automatic assessment. In the lack of a widely accepted standard, a pragmatic solution is to convert content among the existing formats. BabeLO is a programming exercise converter providing services to a network of heterogeneous…

  9. 77 FR 2715 - D'Lo Gas Storage, LLC; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-19

    ... Energy Regulatory Commission D'Lo Gas Storage, LLC; Notice of Application Take notice that on December 29, 2011, D'Lo Gas Storage, LLC (D'Lo), 1002 East St. Mary Blvd., Lafayette, Louisiana 70503, filed in... D'Lo to construct, operate, and maintain a new natural gas storage project to be located in...

  10. Imaging Starspots on LO Pegasi via Light-curve Inversion

    NASA Astrophysics Data System (ADS)

    Harmon, Robert O.; Deskins, R.; Vutisalchavakul, N.

    2007-12-01

    We present maps of the star LO Pegasi obtained via Light-curve Inversion, a computational technique which produces an image of a star's surface features based on variations in the star's observed brightness as dark starspots rotate into and out of view from Earth. LO Pegasi is a rapidly rotating (P=10.17 hr) K8V young solar analog. We inverted BVRI light curves obtained from CCD images acquired on July 7-9 and July 22-23, 2007 at Perkins Observatory in Delaware, OH. Using multiple filters significantly improves the latitude resolution of our maps. Our inversions revealed the presence of a large mid-latitude spot or spotted region on the map from July 7-9, which appears to have evolved into a more complex two-spot configuration by July 22-23. The authors wish to acknowledge the support of the NSF REU Program and the Ohio Wesleyan University Summer Science Research Program.

  11. Liquid oxygen (LO2) propellant conditioning concept testing

    NASA Technical Reports Server (NTRS)

    Perry, Gretchen L. E.; Orth, Michael S.; Mehta, Gopal K.

    1993-01-01

    Testing of a simplified LO2 propellant conditioning concept for future expendable launch vehicles is discussed. Four different concepts are being investigated: no-bleed, low-bleed, use of a recirculation line, and He bubbling. A full-scale test article, which is a facsimile of a propellant feed duct with an attached section to simulate heat input from an LO2 turbopump, is to be tested at the Cold Flow Facility of the Marshall Space Flight Center West Test Area. Work to date includes: design and fabrication of the test article, design of the test facility and initial fabrication, development of a test matrix and test procedures, initial predictions of test output, and heat leak calibration and heat exchanger tests on the test articles.

  12. Liquid Oxygen (LO2) propellant conditioning concept testing

    NASA Technical Reports Server (NTRS)

    Perry, Gretchen L. E.; Orth, Michael S.; Mehta, Gopal K.

    1993-01-01

    Marshall Space Flight Center (MSFC) and industry contractors have undertaken activities to develop a simplified liquid oxygen (LO2) propellant conditioning concept for future expendable launch vehicles. The objective of these activities is to reduce operations costs and timelines and to improve safety of these vehicles. The approach followed has been to identify novel concepts through system level studies and demonstrate the feasibility of these concepts through small-scale and full-scale testing. Testing will also provide data for design guidelines and validation of analytical models. Four different concepts are being investigated: no-bleed, low-bleed, use of a recirculation line, and helium (He) bubbling. This investigation is being done under a Joint Institutional Research and Development (JIRAD) program currently in effect between MSFC and General Dynamics Space Systems (GDSS). A full-scale test article, which is a facsimile of a propellant feed duct with an attached section to simulate heat input from a LO2 turbopump, will be tested at the Cold Flow Facility at MSFC's West Test Area. Liquid nitrogen (LN2), which has similar properties to LO2, will be used in place of LO2 for safety and budget reasons. Work to date includes design and fabrication of the test article, design of the test facility and initial fabrication, development of a test matrix and test procedures, initial predictions of test output, and heat leak calibration and heat exchanger tests on the test article. The tests for all propellant conditioning concepts will be conducted in the summer of 1993, with the final report completed by October, 1993.

  13. LoCuSS: Testing hydrostatic equilibrium in galaxy clusters

    NASA Astrophysics Data System (ADS)

    Smith, G. P.; Mazzotta, P.; Okabe, N.; Ziparo, F.; Mulroy, S. L.; Babul, A.; Finoguenov, A.; McCarthy, I. G.; Lieu, M.; Bahé, Y. M.; Bourdin, H.; Evrard, A. E.; Futamase, T.; Haines, C. P.; Jauzac, M.; Marrone, D. P.; Martino, R.; May, P. E.; Taylor, J. E.; Umetsu, K.

    2016-02-01

    We test the assumption of hydrostatic equilibrium in an X-ray luminosity selected sample of 50 galaxy clusters at 0.15 < z < 0.3 from the Local Cluster Substructure Survey (LoCuSS). Our weak-lensing measurements of M500 control systematic biases to sub-4 per cent, and our hydrostatic measurements of the same achieve excellent agreement between XMM-Newton and Chandra. The mean ratio of X-ray to lensing mass for these 50 clusters is β_X= 0.95± 0.05, and for the 44 clusters also detected by Planck, the mean ratio of Planck mass estimate to LoCuSS lensing mass is β_P= 0.95± 0.04. Based on a careful like-for-like analysis, we find that LoCuSS, the Canadian Cluster Comparison Project, and Weighing the Giants agree on β_P ≃ 0.9-0.95 at 0.15 < z < 0.3. This small level of hydrostatic bias disagrees at ˜5σ with the level required to reconcile Planck cosmology results from the cosmic microwave background and galaxy cluster counts.

  14. Quadrature mixture LO suppression via DSW DAC noise dither

    DOEpatents

    Dubbert, Dale F.; Dudley, Peter A.

    2007-08-21

    A Quadrature Error Corrected Digital Waveform Synthesizer (QECDWS) employs frequency dependent phase error corrections to, in effect, pre-distort the phase characteristic of the chirp to compensate for the frequency dependent phase nonlinearity of the RF and microwave subsystem. In addition, the QECDWS can employ frequency dependent correction vectors to the quadrature amplitude and phase of the synthesized output. The quadrature corrections cancel the radars' quadrature upconverter (mixer) errors to null the unwanted spectral image. A result is the direct generation of an RF waveform, which has a theoretical chirp bandwidth equal to the QECDWS clock frequency (1 to 1.2 GHz) with the high Spurious Free Dynamic Range (SFDR) necessary for high dynamic range radar systems such as SAR. To correct for the problematic upconverter local oscillator (LO) leakage, precision DC offsets can be applied over the chirped pulse using a pseudo-random noise dither. The present dither technique can effectively produce a quadrature DC bias which has the precision required to adequately suppress the LO leakage. A calibration technique can be employed to calculate both the quadrature correction vectors and the LO-nulling DC offsets using the radar built-in test capability.

  15. Non-collinear magnetism calculated using the APW+lo method

    NASA Astrophysics Data System (ADS)

    Laskowski, Robert; Blaha, Peter; Schwarz, Karlheinz; Madsen, Georg K. H.

    2003-03-01

    Our implementation of non-collinear magnetism (NCM) into the APW+lo - WIEN2k code allows calculations of both, the atomic moment approximation (AMA) as well as a full NCM mode, and includes spin-orbit coupling and LDA+U corrections. In AMA only the diagonal part of spin-potential and density matrices inside the atomic spheres (AS) are taken into account, but the complete potential and density matrices are used in the interstitial region. In full NCM also off-diagonal terms inside the AS are considered. In both cases, the implementation utilizes a basis set of rotated spinors inside the AS and pure-spinors in the interstitial. We present ab-initio calculation of UO_2, where three NCM structures are considered, namely, 1k - antiferromagnetic type-I, 2k with momenta pointing in (110) and equivalent directions, and 3k with momenta along (111) directions.

  16. Nonlinear Analysis of the Space Shuttle Superlightweight LO2 Tank. Part 2; Behavior Under 3g End-of-Flight Loads

    NASA Technical Reports Server (NTRS)

    Nemeth, Michael P.; Young, Richard D.; Collins, Timothy J.; Starnes, James H.,Jr.

    1998-01-01

    Results of linear bifurcation and nonlinear analyses of the Space Shuttle super lightweight (SLWT) external liquid-oxygen (LO2) tank are presented for an important end-of-flight loading condition. These results illustrate an important type of response mode for thin-walled shells, that are subjected to combined mechanical and thermal loads, that may be encountered in the design of other liquid-fuel launch vehicles. Linear bifurcation analyses are presented that predict several nearly equal eigenvalues that correspond to local buckling modes in the aft dome of the LO2 tank. In contrast, the nonlinear response phenomenon is shown to consist of a short-wavelength bending deformation in the aft elliptical dome of the LO2 tank that grows in amplitude in a stable manner with increasing load. Imperfection sensitivity analyses are presented that show that the presence of several nearly equal eigenvalues does not lead to a premature general instability mode for the aft dome. For the linear bifurcation and nonlinear analyses, the results show that accurate predictions of the response of the shell generally require a large-scale, high fidelity finite-element model. Results are also presented that show that the SLWT LO2 tank can support loads in excess of approximately 1.9 times the values of the operational loads considered.

  17. Photometry of LO Pegasi in B, V, R colors

    NASA Astrophysics Data System (ADS)

    Csorvási, R.

    2006-09-01

    Variable magnetic activity manifested by starspot distribution is investigated on the single K5-K7 dwarf LO Peg, using one month long photometric observations. We supposed three circular spots for light curve solution. We find variable spot temperature, whose average is 3960 K. The sizes of spots were stable for two spots and one spot showed a significant decrease. Different migration periods on two spots indicate differential rotation, the magnitude of the migration is slow. During the measured 90 stellar rotations (38.5 days) the location of the activity remained on the same hemisphere of the star.

  18. On the LO-polaron dispersion in D dimensions

    NASA Astrophysics Data System (ADS)

    Gerlach, B.; Kalina, F.; Smondyrev, M.

    2003-05-01

    We discuss the (LO)polaron dispersion for arbitrary spatial dimension D. Firstly, we review the existing literature; recent numerical work is critically analyzed. Secondly, we derive novel upper bounds for the dispersion, which incorporate the correct behaviour of the dispersion up to third order of the coupling constant . A totally analytical evaluation is performed in the case D = 1. We compare the upper bounds with previously published lower bounds. Apart from a surrounding of zero dispersion, the relative deviation is on a few-percent scale.

  19. Volumetric HiLo microscopy employing an electrically tunable lens.

    PubMed

    Philipp, Katrin; Smolarski, André; Koukourakis, Nektarios; Fischer, Andreas; Stürmer, Moritz; Wallrabe, Ulrike; Czarske, Jürgen W

    2016-06-27

    Electrically tunable lenses exhibit strong potential for fast motion-free axial scanning in a variety of microscopes. However, they also lead to a degradation of the achievable resolution because of aberrations and misalignment between illumination and detection optics that are induced by the scan itself. Additionally, the typically nonlinear relation between actuation voltage and axial displacement leads to over- or under-sampled frame acquisition in most microscopic techniques because of their static depth-of-field. To overcome these limitations, we present an Adaptive-Lens-High-and-Low-frequency (AL-HiLo) microscope that enables volumetric measurements employing an electrically tunable lens. By using speckle-patterned illumination, we ensure stability against aberrations of the electrically tunable lens. Its depth-of-field can be adjusted a-posteriori and hence enables to create flexible scans, which compensates for irregular axial measurement positions. The adaptive HiLo microscope provides an axial scanning range of 1 mm with an axial resolution of about 4 μm and sub-micron lateral resolution over the full scanning range. Proof of concept measurements at home-built specimens as well as zebrafish embryos with reporter gene-driven fluorescence in the thyroid gland are shown. PMID:27410654

  20. Fast optically sectioned fluorescence HiLo endomicroscopy

    PubMed Central

    Lim, Daryl; Mertz, Jerome

    2012-01-01

    Abstract. We describe a nonscanning, fiber bundle endomicroscope that performs optically sectioned fluorescence imaging with fast frame rates and real-time processing. Our sectioning technique is based on HiLo imaging, wherein two widefield images are acquired under uniform and structured illumination and numerically processed to reject out-of-focus background. This work is an improvement upon an earlier demonstration of widefield optical sectioning through a flexible fiber bundle. The improved device features lateral and axial resolutions of 2.6 and 17 μm, respectively, a net frame rate of 9.5 Hz obtained by real-time image processing with a graphics processing unit (GPU) and significantly reduced motion artifacts obtained by the use of a double-shutter camera. We demonstrate the performance of our system with optically sectioned images and videos of a fluorescently labeled chorioallantoic membrane (CAM) in the developing G. gallus embryo. HiLo endomicroscopy is a candidate technique for low-cost, high-speed clinical optical biopsies. PMID:22463023

  1. Advanced liquid oxygen (LO2) propellant conditioning concept testing

    NASA Technical Reports Server (NTRS)

    Perry, G. L. E.; Suter, J. D.; Turner, S. G.

    1995-01-01

    Advanced methods of liquid oxygen (LO2) propellant conditioning were studied as part of an effort for increasing reliability and operability while reducing cost of future heavy lift launch vehicles. The most promising conditioning concept evaluated was no-bleed (passive recirculation) followed by low-bleed, helium injection, and use of a recirculation line. Full-scale cryogenic testing was performed with a sloped feedline test article to validate models of behavior of LO2 in the feedline and to prove no-bleed feasibility. Test data are also intended to help generate design guidelines for the development of a main propulsion system feed duct. A design-of-experiments matrix of over 100 tests was developed to test all four propellant conditioning concepts and the impact of design parameters on the concepts. Liquid nitrogen was used as the test fluid. The work for this project was conducted from October 1992 through January 1994 at the hydrogen cold flow facility of the west test area of MSFC. Test data have shown that satisfactory temperatures are being obtained for the no-bleed conditioning concept.

  2. Human CD34(lo)CD133(lo) fetal liver cells support the expansion of human CD34(hi)CD133(hi) hematopoietic stem cells.

    PubMed

    Yong, Kylie Su Mei; Keng, Choong Tat; Tan, Shu Qi; Loh, Eva; Chang, Kenneth Te; Tan, Thiam Chye; Hong, Wanjin; Chen, Qingfeng

    2016-09-01

    We have recently discovered a unique CD34(lo)CD133(lo) cell population in the human fetal liver (FL) that gives rise to cells in the hepatic lineage. In this study, we further characterized the biological functions of FL CD34(lo)CD133(lo) cells. Our findings show that these CD34(lo)CD133(lo) cells express markers of both endodermal and mesodermal lineages and have the capability to differentiate into hepatocyte and mesenchymal lineage cells by ex vivo differentiation assays. Furthermore, we show that CD34(lo)CD133(lo) cells express growth factors that are important for human hematopoietic stem cell (HSC) expansion: stem cell factor (SCF), insulin-like growth factor 2 (IGF2), C-X-C motif chemokine 12 (CXCL12), and factors in the angiopoietin-like protein family. Co-culture of autologous FL HSCs and allogenic HSCs derived from cord blood with CD34(lo)CD133(lo) cells supports and expands both types of HSCs.These findings are not only essential for extending our understanding of the HSC niche during the development of embryonic and fetal hematopoiesis but will also potentially benefit adult stem cell transplantations in clinics because expanded HSCs demonstrate the same capacity as primary cells to reconstitute the human immune system and mediate long-term hematopoiesis in vivo. Together, CD34(lo)CD133(lo) cells not only serve as stem/progenitor cells for liver development but are also an essential component of the HSC niche in the human FL. PMID:27593483

  3. Risk assessment of Cumberland unit 2 L-O blades

    SciTech Connect

    Lam, T.C.T.; Puri, A.

    1996-12-31

    Concern about the reliability of the 1,300 mw Cumberland steam turbine units after an unexpected blade tip failure in the fall of 1995 caused TVA to conduct an investigation into the current reliability of the L-O blades. A probabilistic model based on the measured frequencies, damping and material fatigue data was generated. The influence of significant erosion damage on the blade natural frequencies and on the local stresses was estimated. A probabilistic model of the local fatigue limit was generated based on test data. Monte Carlo simulation was employed to estimate the probability of blade failure by comparing the dynamic stress with the fatigue limit. Risk assessment of the blade failure is presented.

  4. Karhunen-Loéve expansion for random earthquake excitations

    NASA Astrophysics Data System (ADS)

    He, Jun

    2015-03-01

    This paper develops a trigonometric-basis-function based Karhunen-Loéve (KL) expansion for simulating random earthquake excitations with known covariance functions. The methods for determining the number of the KL terms and defining the involved random variables are described in detail. The simplified form of the KL expansion is given, whereby the relationship between the KL expansion and the spectral representation method is investigated and revealed. The KL expansion is of high efficiency for simulating long-term earthquake excitations in the sense that it needs a minimum number of random variables, as compared with the spectral representation method. Numerical examples demonstrate the convergence and accuracy of the KL expansion for simulating two commonly-used random earthquake excitation models and estimating linear and nonlinear random responses to the random excitations.

  5. Multivariate Patterns in the Human Object-Processing Pathway Reveal a Shift from Retinotopic to Shape Curvature Representations in Lateral Occipital Areas, LO-1 and LO-2

    PubMed Central

    Vernon, Richard J. W.; Gouws, André D.; Lawrence, Samuel J. D.; Wade, Alex R.

    2016-01-01

    Representations in early visual areas are organized on the basis of retinotopy, but this organizational principle appears to lose prominence in the extrastriate cortex. Nevertheless, an extrastriate region, such as the shape-selective lateral occipital cortex (LO), must still base its activation on the responses from earlier retinotopic visual areas, implying that a transition from retinotopic to “functional” organizations should exist. We hypothesized that such a transition may lie in LO-1 or LO-2, two visual areas lying between retinotopically defined V3d and functionally defined LO. Using a rapid event-related fMRI paradigm, we measured neural similarity in 12 human participants between pairs of stimuli differing along dimensions of shape exemplar and shape complexity within both retinotopically and functionally defined visual areas. These neural similarity measures were then compared with low-level and more abstract (curvature-based) measures of stimulus similarity. We found that low-level, but not abstract, stimulus measures predicted V1–V3 responses, whereas the converse was true for LO, a double dissociation. Critically, abstract stimulus measures were most predictive of responses within LO-2, akin to LO, whereas both low-level and abstract measures were predictive for responses within LO-1, perhaps indicating a transitional point between those two organizational principles. Similar transitions to abstract representations were not observed in the more ventral stream passing through V4 and VO-1/2. The transition we observed in LO-1 and LO-2 demonstrates that a more “abstracted” representation, typically considered the preserve of “category-selective” extrastriate cortex, can nevertheless emerge in retinotopic regions. SIGNIFICANCE STATEMENT Visual areas are typically identified either through retinotopy (e.g., V1–V3) or from functional selectivity [e.g., shape-selective lateral occipital complex (LOC)]. We combined these approaches to explore

  6. Position of glycine substitutions in the triple helix of COL6A1, COL6A2, and COL6A3 is correlated with severity and mode of inheritance in collagen VI myopathies.

    PubMed

    Butterfield, Russell J; Foley, A Reghan; Dastgir, Jahannaz; Asman, Stephanie; Dunn, Diane M; Zou, Yaqun; Hu, Ying; Donkervoort, Sandra; Flanigan, Kevin M; Swoboda, Kathryn J; Winder, Thomas L; Weiss, Robert B; Bönnemann, Carsten G

    2013-11-01

    Glycine substitutions in the conserved Gly-X-Y motif in the triple helical (TH) domain of collagen VI are the most commonly identified mutations in the collagen VI myopathies including Ullrich congenital muscular dystrophy, Bethlem myopathy, and intermediate (INT) phenotypes. We describe clinical and genetic characteristics of 97 individuals with glycine substitutions in the TH domain of COL6A1, COL6A2, or COL6A3 and add a review of 97 published cases, for a total of 194 cases. Clinical findings include severe, INT, and mild phenotypes even from patients with identical mutations. INT phenotypes were most common, accounting for almost half of patients, emphasizing the importance of INT phenotypes to the overall phenotypic spectrum. Glycine substitutions in the TH domain are heavily clustered in a short segment N-terminal to the 17th Gly-X-Y triplet, where they are acting as dominants. The most severe cases are clustered in an even smaller region including Gly-X-Y triplets 10-15, accounting for only 5% of the TH domain. Our findings suggest that clustering of glycine substitutions in the N-terminal region of collagen VI is not based on features of the primary sequence. We hypothesize that this region may represent a functional domain within the triple helix. PMID:24038877

  7. Tolerance of the frequency deviation of LO sources at a MIMO system

    NASA Astrophysics Data System (ADS)

    Xiao, Jiangnan; Li, Xingying; Zhang, Zirang; Xu, Yuming; Chen, Long; Yu, Jianjun

    2015-11-01

    We analyze and simulate the tolerance of frequency offset at a W-band optical-wireless transmission system. The transmission system adopts optical polarization division multiplexing (PDM), and multiple-input multiple-output (MIMO) reception. The transmission signal adopts optical quadrature phase shift keying (QPSK) modulation, and the generation of millimeter-wave is based on the optical heterodyning technique. After 20-km single-mode fiber-28 (SMF-28) transmission, tens of Gb/s millimeter-wave signal is delivered. At the receiver, two millimeter-wave signals are down-converted into electrical intermediate-frequency (IF) signals in the analog domain by mixing with two electrical local oscillators (LOs) with different frequencies. We investigate the different frequency LO effect on the 2×2 MIMO system performance for the first time, finding that the process during DSP of implementing frequency offset estimation (FOE) before cascaded multi-modulus-algorithm (CMMA) equalization can get rid of the inter-channel interference (ICI) and improve system bit-error-ratio (BER) performance in this type of transmission system.

  8. Dexamethasone promotes tolerance in vivo by enriching CD11clo CD40lo tolerogenic macrophages.

    PubMed

    Zheng, Guoxing; Zhong, Shibo; Geng, Yajun; Munirathinam, Gnanasekar; Cha, Isaac; Reardon, Catherine; Getz, Godfrey S; van Rooijen, Nico; Kang, Youmin; Wang, Bin; Chen, Aoshuang

    2013-01-01

    We previously showed that antigen immunization in the presence of the immunosuppressant dexamethasone (a strategy we termed "suppressed immunization") could tolerize established recall responses of T cells. However, the mechanism by which dexamethasone acts as a tolerogenic adjuvant has remained unclear. In the present study, we show that dexamethasone enriches CD11c(lo) CD40(lo) macrophages in a dose-dependent manner in the spleen and peripheral lymph nodes of mice by depleting all other CD11c(+) CD40(+) cells including dendritic cells. The enriched macrophages display a distinct MHC class II (MHC II)(lo) CD86(hi) phenotype. Upon activation by antigen in vivo, CD11c(lo) CD40(lo) macrophages upregulate IL-10, a classic marker for tolerogenic antigen-presenting cells, and elicit a serum IL-10 response. When presenting antigen in vivo, these cells do not elicit recall responses from memory T cells, but rather stimulate the expansion of antigen-specific regulatory T cells. Moreover, the depletion of CD11c(lo) CD40(lo) macrophages during suppressed immunization diminishes the tolerogenic efficacy of the treatment. These results indicate that dexamethasone acts as a tolerogenic adjuvant partly by enriching the CD11c(lo) CD40(lo) tolerogenic macrophages. PMID:23001956

  9. Going LO (laparoscopic oviductal) for ET and AI in Felids – Challenges, Strategies and Successes

    PubMed Central

    Swanson, WF

    2012-01-01

    Contents Embryo transfer (ET) and artificial insemination (AI) are potentially invaluable techniques for the propagation and management of genetically valuable domestic cat and endangered nondomestic cat populations. Many of the challenges that impair the effective application of ET and AI in felids may be overcome by using laparoscopic oviductal (LO) approaches. LO-ET and LO-AI are minimally-invasive procedures, requiring only two small skin incisions for insertion of a laparoscope and grasping forceps into the abdominal cavity to permit visualization and catheterization of the oviduct for embryo or semen deposition. With concurrent improvements in embryo culture systems and ovarian synchronization protocols, LO-ET has proven effective over the past decade for propagation of laboratory cats, cat models of hereditary disease and nondomestic cats. To date, viable offspring have been produced following LO-ET of non-frozen and frozen-thawed IVF-derived embryos in eight cat hereditary disease models and two nondomestic cat species, the ocelot and sand cat. LO-AI with low sperm numbers (~2–8 million motile) has shown similar efficacy to LO-ET, resulting in high pregnancy percentages (50–70%) following insemination of gonadotropin-treated domestic cats. Multiple kittens also have been produced in two hereditary disease models following LO-AI with frozen semen, and both ocelot and Pallas’ cat kittens have been born after LO-AI with freshly-collected semen. The application of LO-ET and LO-AI to felids has resulted in substantial improvement in the efficiency of assisted reproduction for genetic management of these invaluable domestic cat and wild cat populations. PMID:23279483

  10. A SCUBA-2 survey of FeLoBAL QSOs. Are FeLoBALs in a `transition phase' between ULIRGs and QSOs?

    NASA Astrophysics Data System (ADS)

    Violino, Giulio; Coppin, Kristen E. K.; Stevens, Jason A.; Farrah, Duncan; Geach, James E.; Alexander, Dave M.; Hickox, Ryan; Smith, Daniel J. B.; Wardlow, Julie L.

    2016-04-01

    It is thought that a class of broad absorption line (BAL) QSOs, characterized by Fe absorption features in their UV spectra (called `FeLoBALs'), could mark a transition stage between the end of an obscured starburst event and a youthful QSO beginning to shed its dust cocoon, where Fe has been injected into the interstellar medium by the starburst. To test this hypothesis, we have undertaken deep Submillimetre Common-User Bolometer Array 2 (SCUBA-2) 850 μm observations of a sample of 17 FeLoBAL QSOs with 0.89 ≤ z ≤ 2.78 and -23.31 ≤ MB ≤ -28.50 to directly detect an excess in the thermal emission of the dust which would probe enhanced star formation activity. We find that FeLoBALs are not luminous sources in the sub-mm, none of them are individually detected at 850 μm, nor as a population through stacking (Fs = 1.14 ± 0.58 mJy). Statistical and survival analyses reveal that FeLoBALs have sub-mm properties consistent with BAL and non-BAL QSOs with matched redshifts and magnitudes. An Spectral Energy Distribution fitting analysis shows that the far-infrared emission is dominated by active galactic nuclei activity, and a starburst component is required only in 6/17 sources of our sample; moreover the integrated total luminosity of 16/17 sources is L ≥ 1012 L⊙, high enough to classify FeLoBALs as infrared luminous. In conclusion, we do not find any evidence in support of FeLoBAL QSOs being a transition population between an ultraluminous infrared galaxy (ULIRG) and an unobscured QSO; in particular, FeLoBALs are not characterized by a cold starburst which would support this hypothesis.

  11. Resonant tunnelling diode oscillator as an alternative LO for SIS receiver applications

    NASA Technical Reports Server (NTRS)

    Blundell, R.; Papa, D. C.; Brown, E. R.; Parker, C. D.

    1993-01-01

    The resonant tunnelling diode (RTD) oscillator has been demonstrated for the first time as a local oscillator (LO) in a heterodyne receiver. Noise measurements made on a sensitive 200 GHz superconductor-insulator-superconductor receiver using both a multiplied Gunn diode and an RTD oscillator as the LO revealed no difference in receiver noise as a function of oscillator type.

  12. A ROACH Based Data Acquisition System for the Low Frequency All Sky Monitor (LoFASM)

    NASA Astrophysics Data System (ADS)

    Dartez, Louis P.; Jenet, F.; Cohen, S.; Creighton, T. D.; Ford, A.; Garcia, A.; Hicks, B.; Hinojosa, J.; Kassim, N. E.; Longoria, C.; Lunsford, G.; Mata, A.; Miller, R. B.; Price, R. H.; Quintero, L.; Ray, P. S.; Reser, J.; Rivera, J.; Stovall, K.; Taylor, G. B.

    2013-01-01

    The Low Frequency All Sky Monitor (LoFASM) is a distributed array of dipole antennas that are sensitive to radio frequencies from 5 to 88 MHz. The primary science goals will be the detection and study of low-frequency radio transients. LoFASM consists of antennas and front end electronics that were originally developed for the Long Wavelength Array (LWA) by the U.S. Naval Research Lab, the University of New Mexico, Virginia Tech, and the Jet Propulsion Laboratory. LoFASM, funded by the U.S. Department of Defense, will initially consist of 4 stations, each consisting of 12 dual-polarization dipole antenna stands. The signals received by LoFASM are digitized and processed using Reconfigurable Open Architecture Computing Hardware (ROACH) boards. This poster will describe the LoFASM project with an emphasis on the ROACH data processing pipe-line.

  13. The Low Redshift survey at Calar Alto (LoRCA)

    NASA Astrophysics Data System (ADS)

    Comparat, J.; Chuang, C.-H.; Rodríguez-Torres, S.; Pellejero-Ibanez, M.; Prada, F.; Yepes, G.; Courtois, H. M.; Zhao, G.-B.; Wang, Y.; Sanchez, J.; Maraston, C.; Metcalf, R. Benton; Peiro-Perez, J.; Kitaura, F. S.; Pérez, E.; González Delgado, R. M.

    2016-05-01

    The Baryon Acoustic Oscillation (BAO) feature in the power spectrum of galaxies provides a standard ruler to measure the accelerated expansion of the Universe. To extract all available information about dark energy, it is necessary to measure a standard ruler in the local, z < 0.2, universe where dark energy dominates most the energy density of the Universe. Though the volume available in the local universe is limited, it is just big enough to measure accurately the long 100 h-1 Mpc wave-mode of the BAO. Using cosmological N-body simulations and approximate methods based on Lagrangian perturbation theory, we construct a suite of a thousand light-cones to evaluate the precision at which one can measure the BAO standard ruler in the local universe. We find that using the most massive galaxies on the full sky (34 000 deg2), i.e. a K2MASS < 14 magnitude-limited sample, one can measure the BAO scale up to a precision of 4 per cent (˜1.2 per cent using reconstruction). We also find that such a survey would help to detect the dynamics of dark energy. Therefore, we propose a 3-year long observational project, named the Low Redshift survey at Calar Alto, to observe spectroscopically about 200 000 galaxies in the northern sky to contribute to the construction of aforementioned galaxy sample. The suite of light-cones is made available to the public.

  14. Identification of Raman-active phonon modes in oriented platelets of InN and polycrystalline InN

    NASA Astrophysics Data System (ADS)

    Dyck, J. S.; Kim, K.; Limpijumnong, S.; Lambrecht, W. R. L.; Kash, K.; Angus, J. C.

    2000-04-01

    We report on micro-Raman studies on both randomly oriented polycrystals and groups of oriented, faceted platelets of indium nitride grown from the melt at subatmospheric pressures. Phonon modes were assigned as A1TO=445, E1TO=472, E2(2)=488, and A1LO=588 cm-1. The FWHM of the E2(2) peak of 2.5 cm -1 is the narrowest reported to date for InN. The measured TO phonon frequencies were compared to those calculated from first principles and excellent agreement was found. The results are discussed in the context of previously reported Raman experiments on heteroepitaxial, and hence strained, layers of InN.

  15. TriLoNet: Piecing Together Small Networks to Reconstruct Reticulate Evolutionary Histories.

    PubMed

    Oldman, James; Wu, Taoyang; van Iersel, Leo; Moulton, Vincent

    2016-08-01

    Phylogenetic networks are a generalization of evolutionary trees that can be used to represent reticulate processes such as hybridization and recombination. Here, we introduce a new approach called TriLoNet (Trinet Level- one Network algorithm) to construct such networks directly from sequence alignments which works by piecing together smaller phylogenetic networks. More specifically, using a bottom up approach similar to Neighbor-Joining, TriLoNet constructs level-1 networks (networks that are somewhat more general than trees) from smaller level-1 networks on three taxa. In simulations, we show that TriLoNet compares well with Lev1athan, a method for reconstructing level-1 networks from three-leaved trees. In particular, in simulations we find that Lev1athan tends to generate networks that overestimate the number of reticulate events as compared with those generated by TriLoNet. We also illustrate TriLoNet's applicability using simulated and real sequence data involving recombination, demonstrating that it has the potential to reconstruct informative reticulate evolutionary histories. TriLoNet has been implemented in JAVA and is freely available at https://www.uea.ac.uk/computing/TriLoNet. PMID:27189565

  16. Contrast Invariant Interest Point Detection by Zero-Norm LoG Filter.

    PubMed

    Zhenwei Miao; Xudong Jiang; Kim-Hui Yap

    2016-01-01

    The Laplacian of Gaussian (LoG) filter is widely used in interest point detection. However, low-contrast image structures, though stable and significant, are often submerged by the high-contrast ones in the response image of the LoG filter, and hence are difficult to be detected. To solve this problem, we derive a generalized LoG filter, and propose a zero-norm LoG filter. The response of the zero-norm LoG filter is proportional to the weighted number of bright/dark pixels in a local region, which makes this filter be invariant to the image contrast. Based on the zero-norm LoG filter, we develop an interest point detector to extract local structures from images. Compared with the contrast dependent detectors, such as the popular scale invariant feature transform detector, the proposed detector is robust to illumination changes and abrupt variations of images. Experiments on benchmark databases demonstrate the superior performance of the proposed zero-norm LoG detector in terms of the repeatability and matching score of the detected points as well as the image recognition rate under different conditions. PMID:26302514

  17. LoCoH: Non-parameteric kernel methods for constructing home ranges and utilization distributions

    USGS Publications Warehouse

    Getz, Wayne M.; Fortmann-Roe, Scott; Cross, Paul C.; Lyons, Andrew J.; Ryan, Sadie J.; Wilmers, Christopher C.

    2007-01-01

    Parametric kernel methods currently dominate the literature regarding the construction of animal home ranges (HRs) and utilization distributions (UDs). These methods frequently fail to capture the kinds of hard boundaries common to many natural systems. Recently a local convex hull (LoCoH) nonparametric kernel method, which generalizes the minimum convex polygon (MCP) method, was shown to be more appropriate than parametric kernel methods for constructing HRs and UDs, because of its ability to identify hard boundaries (e.g., rivers, cliff edges) and convergence to the true distribution as sample size increases. Here we extend the LoCoH in two ways: ‘‘fixed sphere-of-influence,’’ or r -LoCoH (kernels constructed from all points within a fixed radius r of each reference point), and an ‘‘adaptive sphere-of-influence,’’ or a -LoCoH (kernels constructed from all points within a radius a such that the distances of all points within the radius to the reference point sum to a value less than or equal to a ), and compare them to the original ‘‘fixed-number-of-points,’’ or k -LoCoH (all kernels constructed from k -1 nearest neighbors of root points). We also compare these nonparametric LoCoH to parametric kernel methods using manufactured data and data collected from GPS collars on African buffalo in the Kruger National Park, South Africa. Our results demonstrate that LoCoH methods are superior to parametric kernel methods in estimating areas used by animals, excluding unused areas (holes) and, generally, in constructing UDs and HRs arising from the movement of animals influenced by hard boundaries and irregular structures (e.g., rocky outcrops). We also demonstrate that a -LoCoH is generally superior to k - and r -LoCoH (with software for all three methods available at http://locoh.cnr.berkeley.edu).

  18. LoCoH: Nonparameteric Kernel Methods for Constructing Home Ranges and Utilization Distributions

    PubMed Central

    Getz, Wayne M.; Fortmann-Roe, Scott; Wilmers, Christopher C.

    2007-01-01

    Parametric kernel methods currently dominate the literature regarding the construction of animal home ranges (HRs) and utilization distributions (UDs). These methods frequently fail to capture the kinds of hard boundaries common to many natural systems. Recently a local convex hull (LoCoH) nonparametric kernel method, which generalizes the minimum convex polygon (MCP) method, was shown to be more appropriate than parametric kernel methods for constructing HRs and UDs, because of its ability to identify hard boundaries (e.g., rivers, cliff edges) and convergence to the true distribution as sample size increases. Here we extend the LoCoH in two ways: “fixed sphere-of-influence,” or r-LoCoH (kernels constructed from all points within a fixed radius r of each reference point), and an “adaptive sphere-of-influence,” or a-LoCoH (kernels constructed from all points within a radius a such that the distances of all points within the radius to the reference point sum to a value less than or equal to a), and compare them to the original “fixed-number-of-points,” or k-LoCoH (all kernels constructed from k-1 nearest neighbors of root points). We also compare these nonparametric LoCoH to parametric kernel methods using manufactured data and data collected from GPS collars on African buffalo in the Kruger National Park, South Africa. Our results demonstrate that LoCoH methods are superior to parametric kernel methods in estimating areas used by animals, excluding unused areas (holes) and, generally, in constructing UDs and HRs arising from the movement of animals influenced by hard boundaries and irregular structures (e.g., rocky outcrops). We also demonstrate that a-LoCoH is generally superior to k- and r-LoCoH (with software for all three methods available at http://locoh.cnr.berkeley.edu). PMID:17299587

  19. Higgs boson gluon-fusion production beyond threshold in N3LO QCD

    DOE PAGESBeta

    Anastasiou, Charalampos; Duhr, Claude; Dulat, Falko; Furlan, Elisabetta; Gehrmann, Thomas; Herzog, Franz; Mistlberger, Bernhard

    2015-03-18

    In this study, we compute the gluon fusion Higgs boson cross-section at N3LO through the second term in the threshold expansion. This calculation constitutes a major milestone towards the full N3LO cross section. Our result has the best formal accuracy in the threshold expansion currently available, and includes contributions from collinear regions besides subleading corrections from soft and hard regions, as well as certain logarithmically enhanced contributions for general kinematics. We use our results to perform a critical appraisal of the validity of the threshold approximation at N3LO in perturbative QCD.

  20. Berreman mode and epsilon near zero mode.

    PubMed

    Vassant, Simon; Hugonin, Jean-Paul; Marquier, Francois; Greffet, Jean-Jacques

    2012-10-01

    In this paper, we discuss the existence of an electromagnetic mode propagating in a thin dielectric film deposited on a metallic film at the particular frequency such that the dielectric permittivity vanishes. We discuss the remarkable properties of this mode in terms of extreme subwavelength mode confinment and its potential applications. We also discuss the link between this mode, the IR absorption peak on a thin dielectric film known as Berreman effect and the surface phonon polariton mode at the air/dielectric interface. Finally, we establish a connection with the polarization shift occuring in quantum wells. PMID:23188363

  1. Development of HiLo Microscope and its use in In-Vivo Applications

    NASA Astrophysics Data System (ADS)

    Patel, Shreyas J.

    The functionality of achieving optical sectioning in biomedical research is invaluable as it allows for visualization of a biological sample at different depths while being free of background scattering. Most current microscopy techniques that offer optical sectioning, unfortunately, require complex instrumentation and thus are generally costly. HiLo microscopy, on the other hand, offers the same functionality and advantage at a relatively low cost. Hence, the work described in this thesis involves the design, build, and application of a HiLo microscope. More specifically, a standalone HiLo microscope was built in addition to implementing HiLo microscopy on a standard fluorescence microscope. In HiLo microscopy, optical sectioning is achieved by acquiring two different types of images per focal plane. One image is acquired under uniform illumination and the other is acquired under speckle illumination. These images are processed using an algorithm that extracts in-focus information and removes features and glare that occur as a result of background fluorescence. To show the benefits of the HiLo microscopy, several imaging experiments on various samples were performed under a HiLo microscope and compared against a traditional fluorescence microscope and a confocal microscope, which is considered the gold standard in optical imaging. In-vitro and ex-vivo imaging was performed on a set of pollen grains, and optically cleared mouse brain and heart slices. Each of these experiments showed great reduction in background scattering at different depths under HiLo microscopy. More importantly, HiLo imaging of optically cleared heart slice demonstrated emergence of different vasculature at different depths. Reduction of out-of-focus light increased the spatial resolution and allowed better visualization of capillary vessels. Furthermore, HiLo imaging was tested in an in-vivo model of a rodent dorsal window chamber model. When imaging the same sample under confocal microscope

  2. Experimental application of the Karhunen-Lo{grave e}ve decomposition to the study of modal interactions in a mechanical oscillator

    SciTech Connect

    Cusumano, J.P.

    1996-06-01

    The results of an experimental study of a magnetically-kicked flexible-beam oscillator are presented. The dynamics of the autonomous system are observed using nine strain gauges distributed along the length of the beam. The Karhunen-Lo{grave e}ve decomposition is used to study the dimensionality of the system in terms of modal interactions. Two modes which interact to produce the observed dynamics over a wide range of the system{close_quote}s bifurcation parameter are found. It is concluded that a two degree of freedom model is adequate to describe the observed steady-state phenomena. {copyright} {ital 1996 American Institute of Physics.}

  3. Effect of Propellant Flowrate and Purity on Carbon Deposition in LO2/Methane Gas Generators

    NASA Technical Reports Server (NTRS)

    Bossard, J. A.; Burkhardt, W. M.; Niiya, K. Y.; Braam, F.

    1989-01-01

    The generation and deposition of carbon was studied in the Carbon Deposition Program using subscale hardware with LO2/Liquid Natural Gas (LNG) and LO2/Methane propellants at low mixture ratios. The purpose of the testing was to evaluate the effect of methane purity and full scale injection density on carbon deposition. The LO2/LNG gas generator/preburner testing was performed at mixture ratios between 0.24 and 0.58 and chamber pressures from 5.8 to 9.4 MPa (840 to 1370 psia). A total of seven 200 second duration tests were performed. The LNG testing occurred at low injection densities, similar to the previous LO2/RP-1, LO2/propane, and LO2/methane testing performed on the carbon deposition program. The current LO2/methane test series occurred at an injection density factor of approximately 10 times higher than the previous testing. The high injection density LO2/methane testing was performed at mixture ratios between from 0.23 to 0.81 and chamber pressures from 6.4 to 15.2 MPa (925 to 2210 psia). A total of nine high injection density tests were performed. The testing performed demonstrated that low purity methane (LNG) did not produce any detectable change in carbon deposition when compared to pure methane. In addition, the C* performance and the combustion gas temperatures measured were similar to those obtained for pure methane. Similar results were obtained testing pure methane at higher propellant injection densities with coarse injector elements.

  4. Measurement Properties of the Low Back Activity Confidence Scale (LoBACS).

    PubMed

    Davenport, Todd E; Cleland, Joshua A; Yamada, Kimiko A; Kulig, Kornelia

    2016-06-01

    The purpose of this study was to determine the measurement properties of the Low Back Activity Confidence Scale (LoBACS) in individuals with post-acute low back pain (LBP) receiving nonsurgical intervention, including construct validity, factorial validity, and internal consistency reliability. Data were analyzed from an existing randomized clinical trial involving 112 patients with LBP. Evidence for convergent validity was observed through significant correlations between LoBACS subscale scores and other function, pain, and psychobehavioral measures. LoBACS subscales accounted for 36% of the unique variance in dependent variable measurements, suggesting a satisfactory level of statistical divergence between the LoBACS and other psychobehavioral measurements in this study. Cronbach's α ranged from .88 to .92 for LoBACS subscales, and item-total correlations exceeded .6, indicating high internal consistency reliability. Principal axis factoring confirmed the hypothesized three-subscale structure by correctly classifying 14 of the 15 items. These findings indicate the LoBACS is valid and internally consistent to measure domain-specific self-efficacy beliefs. PMID:24686745

  5. Bandgap measurements and the peculiar splitting of E2H phonon modes of InxAl1-xN nanowires grown by plasma assisted molecular beam epitaxy

    NASA Astrophysics Data System (ADS)

    Tangi, Malleswararao; Mishra, Pawan; Janjua, Bilal; Ng, Tien Khee; Anjum, Dalaver H.; Prabaswara, Aditya; Yang, Yang; Albadri, Abdulrahman M.; Alyamani, Ahmed Y.; El-Desouki, Munir M.; Ooi, Boon S.

    2016-07-01

    The dislocation free InxAl1-xN nanowires (NWs) are grown on Si(111) by nitrogen plasma assisted molecular beam epitaxy in the temperature regime of 490 °C-610 °C yielding In composition ranges over 0.50 ≤ x ≤ 0.17. We study the optical properties of these NWs by spectroscopic ellipsometry (SE), photoluminescence, and Raman spectroscopies since they possesses minimal strain with reduced defects comparative to the planar films. The optical bandgap measurements of InxAl1-xN NWs are demonstrated by SE where the absorption edges of the NW samples are evaluated irrespective of substrate transparency. A systematic Stoke shift of 0.04-0.27 eV with increasing x was observed when comparing the micro-photoluminescence spectra with the Tauc plot derived from SE. The micro-Raman spectra in the NWs with x = 0.5 showed two-mode behavior for A1(LO) phonons and single mode behavior for E2H phonons. As for x = 0.17, i.e., high Al content, we observed a peculiar E2H phonon mode splitting. Further, we observe composition dependent frequency shifts. The 77 to 600 K micro-Raman spectroscopy measurements show that both AlN- and InN-like modes of A1(LO) and E2H phonons in InxAl1-xN NWs are redshifted with increasing temperature, similar to that of the binary III group nitride semiconductors. These studies of the optical properties of the technologically important InxAl1-xN nanowires will path the way towards lasers and light-emitting diodes in the wavelength of the ultra-violet and visible range.

  6. Study of a condition for the mode conversion from purely perpendicular electrostatic waves to electromagnetic waves

    NASA Astrophysics Data System (ADS)

    Kalaee, Mohammad Javad; Katoh, Yuto

    2016-07-01

    One of the mechanisms for generating electromagnetic plasma waves (Z-mode and LO-mode) is mode conversion from electrostatic waves into electromagnetic waves in inhomogeneous plasma. Herein, we study a condition required for mode conversion of electrostatic waves propagating purely perpendicular to the ambient magnetic field, by numerically solving the full dispersion relation. An approximate model is derived describing the coupling between electrostatic waves (hot plasma Bernstein mode) and Z-mode waves at the upper hybrid frequency. The model is used to study conditions required for mode conversion from electrostatic waves (electrostatic electron cyclotron harmonic waves, including Bernstein mode) into electromagnetic plasma waves (LO-mode). It is shown that for mode conversion to occur in inhomogeneous plasma, the angle between the boundary surface and the magnetic field vector should be within a specific range. The range of the angle depends on the norm of the k vector of waves at the site of mode conversion in the inhomogeneous region. The present study reveals that inhomogeneity alone is not a sufficient condition for mode conversion from electrostatic waves to electromagnetic plasma waves and that the angle between the magnetic field and the density gradient plays an important role in the conversion process.

  7. List mode multichannel analyzer

    DOEpatents

    Archer, Daniel E.; Luke, S. John; Mauger, G. Joseph; Riot, Vincent J.; Knapp, David A.

    2007-08-07

    A digital list mode multichannel analyzer (MCA) built around a programmable FPGA device for onboard data analysis and on-the-fly modification of system detection/operating parameters, and capable of collecting and processing data in very small time bins (<1 millisecond) when used in histogramming mode, or in list mode as a list mode MCA.

  8. Laminarin-induced apoptosis in human colon cancer LoVo cells

    PubMed Central

    JI, CHEN-FENG; JI, YU-BIN

    2014-01-01

    A number of scientific studies have revealed that laminarin has antitumor effects. Therefore, the aim of the present study was to investigate the apoptosis of LoVo cells and the underlying mechanisms induced by laminarin. LoVo cells were treated with various concentrations of laminarin and fluorescence-inverted microscopy was used to observe the morphology of LoVo cells treated with laminarin. In addition, western blotting was performed to analyze the expression levels of death receptor (DR)4, DR5, TNF-related apoptosis-inducing ligand (TRAIL), Fas-associated protein with death domain (FADD), caspase-8, caspase-3, Bid and tBid. Flow cytometry was conducted to analyze the expressions of Bcl-2 and Bax, and spectrophotometry was performed to quantify the activity of caspases-8, -3, -6 and -7. Following the treatment of LoVo cells with laminarin for 24 h, the expression levels of DR4, DR5, TRAIL, FADD, Bid, tBid and Bax were observed to be upregulated, whereas the expression levels of pro-caspase-8, pro-caspase-3 and Bcl-2 were downregulated. In addition, the activities of casapse-8, -3, -6 and -7 were observed to increase, which was a significant difference when compared with those of the control group. Therefore, laminarin is considered to induce the apoptosis of LoVo cells, which may occur via a DR pathway, suggesting that laminarin may be a potent agent for cancer treatment. PMID:24765209

  9. Optically sectioned in vivo imaging with speckle illumination HiLo microscopy

    NASA Astrophysics Data System (ADS)

    Lim, Daryl; Ford, Tim N.; Chu, Kengyeh K.; Mertz, Jerome

    2011-01-01

    We present a simple wide-field imaging technique, called HiLo microscopy, that is capable of producing optically sectioned images in real time, comparable in quality to confocal laser scanning microscopy. The technique is based on the fusion of two raw images, one acquired with speckle illumination and another with standard uniform illumination. The fusion can be numerically adjusted, using a single parameter, to produce optically sectioned images of varying thicknesses with the same raw data. Direct comparison between our HiLo microscope and a commercial confocal laser scanning microscope is made on the basis of sectioning strength and imaging performance. Specifically, we show that HiLo and confocal 3-D imaging of a GFP-labeled mouse brain hippocampus are comparable in quality. Moreover, HiLo microscopy is capable of faster, near video rate imaging over larger fields of view than attainable with standard confocal microscopes. The goal of this paper is to advertise the simplicity, robustness, and versatility of HiLo microscopy, which we highlight with in vivo imaging of common model organisms including planaria, C. elegans, and zebrafish.

  10. Optically sectioned in vivo imaging with speckle illumination HiLo microscopy.

    PubMed

    Lim, Daryl; Ford, Tim N; Chu, Kengyeh K; Mertz, Jerome

    2011-01-01

    We present a simple wide-field imaging technique, called HiLo microscopy, that is capable of producing optically sectioned images in real time, comparable in quality to confocal laser scanning microscopy. The technique is based on the fusion of two raw images, one acquired with speckle illumination and another with standard uniform illumination. The fusion can be numerically adjusted, using a single parameter, to produce optically sectioned images of varying thicknesses with the same raw data. Direct comparison between our HiLo microscope and a commercial confocal laser scanning microscope is made on the basis of sectioning strength and imaging performance. Specifically, we show that HiLo and confocal 3-D imaging of a GFP-labeled mouse brain hippocampus are comparable in quality. Moreover, HiLo microscopy is capable of faster, near video rate imaging over larger fields of view than attainable with standard confocal microscopes. The goal of this paper is to advertise the simplicity, robustness, and versatility of HiLo microscopy, which we highlight with in vivo imaging of common model organisms including planaria, C. elegans, and zebrafish. PMID:21280920

  11. Demonstration of simultaneous mode conversion and demultiplexing for mode and wavelength division multiplexing systems based on tilted few-mode fiber Bragg gratings.

    PubMed

    Gao, Ya; Sun, Junqiang; Chen, Guodong; Sima, Chaotan

    2015-04-20

    We experimentally demonstrate mode conversion by exploiting optical reflection of tilted few-mode fiber Bragg grating (FM-FBG). Mode conversions from LP(01) mode to higher symmetric and asymmetric modes are achieved, and more than 99.5% conversion efficiency from LP(01) to LP(11) mode is obtained using a 1.6°-tilted FM-FBG. Influences of the weakly tilted FM-FBG parameters on the property of mode conversion is analyzed and discussed. A simultaneous mode conversion and demultiplexing scheme for 4-mode × 3-wavelength multiplexing transmission is proposed and the modal crosstalk is analyzed based on the transmission spectra of the tilted FM-FBGs. The proposed approach shows potential applications in mode and wavelength division multiplexing communication systems. PMID:25969037

  12. Local and normal modes: A classical perspective

    NASA Astrophysics Data System (ADS)

    Jaffé, Charles; Brumer, Paul

    1980-12-01

    Normal and local mode behavior in molecular systems and the transition between them is explored using nonlinear mechanics techniques. Significant insight into this behavior and into the structure of phase space results from a generalized definition of local and normal modes and the associated identification of normal modes as a (1:1) resonance between local zeroth order oscillators. In addition to qualitative insight, this approach yields a simple formula [Eq. (28)] for the level of excitation at which local modes become possible. Applications to H2O and to the overtone spectroscopy of the dihalomethanes, benzene, and TMS are provided.

  13. A Study of LoRa: Long Range & Low Power Networks for the Internet of Things.

    PubMed

    Augustin, Aloÿs; Yi, Jiazi; Clausen, Thomas; Townsley, William Mark

    2016-01-01

    LoRa is a long-range, low-power, low-bitrate, wireless telecommunications system, promoted as an infrastructure solution for the Internet of Things: end-devices use LoRa across a single wireless hop to communicate to gateway(s), connected to the Internet and which act as transparent bridges and relay messages between these end-devices and a central network server. This paper provides an overview of LoRa and an in-depth analysis of its functional components. The physical and data link layer performance is evaluated by field tests and simulations. Based on the analysis and evaluations, some possible solutions for performance enhancements are proposed. PMID:27618064

  14. Implementation and Evaluation of the Enhanced Header Compression (IPHC) for 6LoWPAN

    NASA Astrophysics Data System (ADS)

    Ludovici, Alessandro; Calveras, Anna; Catalan, Marisa; Gómez, Carles; Paradells, Josep

    6LoWPAN defines how to carry IPv6 packets over IEEE 802.15.4 low power wireless or sensor networks. Limited bandwidth, memory and energy resources require a careful application of IPv6 in a LoWPAN. The IEEE 802.15.4 standard defines a maximum frame size of 127 bytes that decreases to 102 bytes considering the header overhead. A further reduction is due to the security, network and transport protocols header overhead that, in case of IPv6 and UDP, leave only 33 bytes for application data. A compression algorithm is necessary in order to reduce the overhead and save space in data payload. This paper describes and compares the proposed IPv6 header compression mechanisms for 6LoWPAN environments.

  15. Improving high resolution retinal image quality using speckle illumination HiLo imaging

    PubMed Central

    Zhou, Xiaolin; Bedggood, Phillip; Metha, Andrew

    2014-01-01

    Retinal image quality from flood illumination adaptive optics (AO) ophthalmoscopes is adversely affected by out-of-focus light scatter due to the lack of confocality. This effect is more pronounced in small eyes, such as that of rodents, because the requisite high optical power confers a large dioptric thickness to the retina. A recently-developed structured illumination microscopy (SIM) technique called HiLo imaging has been shown to reduce the effect of out-of-focus light scatter in flood illumination microscopes and produce pseudo-confocal images with significantly improved image quality. In this work, we adopted the HiLo technique to a flood AO ophthalmoscope and performed AO imaging in both (physical) model and live rat eyes. The improvement in image quality from HiLo imaging is shown both qualitatively and quantitatively by using spatial spectral analysis. PMID:25136486

  16. Large mode radius resonators

    NASA Technical Reports Server (NTRS)

    Harris, Michael R.

    1987-01-01

    Resonator configurations permitting operation with large mode radius while maintaining good transverse mode discrimination are considered. Stable resonators incorporating an intracavity telescope and unstable resonator geometries utilizing an output coupler with a Gaussian reflectivity profile are shown to enable large radius single mode laser operation. Results of heterodyne studies of pulsed CO2 lasers with large (11mm e sup-2 radius) fundamental mode sizes are presented demonstrating minimal frequency sweeping in accordance with the theory of laser-induced medium perturbations.

  17. Patterned flattened modes.

    PubMed

    Messerly, Michael J; Pax, Paul H; Dawson, Jay W

    2013-09-01

    We show that field-flattened strands may be added to and arbitrarily positioned within a field-flattened shell to create patterned, flattened modes. Patterning does not alter the effective index or flatness of the flattened mode but does alter the characteristics of other modes; we show that it can improve a flattened mode's bend performance significantly. Patterning provides a new and potentially valuable waveguide design tool that may lead to higher-power transport and laser fibers. PMID:23988948

  18. A1C test

    MedlinePlus

    HbA1C test; Glycated hemoglobin test; Glycosylated hemoglobin test; Hemoglobin glycosylated test; Glycohemoglobin test ... have recently eaten does not affect the A1C test, so you do not need to fast to ...

  19. Integrated mode converter for mode division multiplexing

    NASA Astrophysics Data System (ADS)

    Perez-Galacho, Diego; Alonso-Ramos, Carlos Alberto; Marris-Morini, Delphine; Vakarin, Vladyslav; Le Roux, Xavier; Ortega-Moñux, Alejandro; Wangüemert-Perez, Juan Gonzalo; Vivien, Laurent

    2016-05-01

    The ever growing demands of bandwidth in optical communication systems are making traditional Wavelength Division Multiplexing (WDM) based systems to reach its limit. In order to cope with future bandwidth demand is necessary to use new levels of orthogonality, such as the waveguide mode or the polarization state. Mode Division Multiplexing (MDM) has recently attracted attention as a possible solution to increase aggregate bandwidth. In this work we discuss the proposition a of mode converter that can cover the whole C-Band of optical communications. The Mode Converter is based on two Multimode Interference (MMI) couplers and a phase shifter. Insertion loss (IL) below 0.2 dB and Extinction ratio (ER) higher than 20 dB in a broad bandwidth range of 1.5 μm to 1.6 μm have been estimated. The total length of the device is less than 30 μm.

  20. Analysis of 100-lb(sub f) (445-N) LO2-LCH4 Reaction Control Engine Impulse Bit Performance

    NASA Technical Reports Server (NTRS)

    Marshall, William M.; Klenhenz, Julie E.

    2012-01-01

    Recently, liquid oxygen-liquid methane (LO2-LCH4) has been considered as a potential green propellant alternative for future exploration missions. The Propulsion and Cryogenic Advanced Development (PCAD) project was tasked by NASA to develop this propulsion combination to enable safe and cost-effective exploration missions. To date, limited experience with such combinations exist, and as a result a comprehensive test program is critical to demonstrating with the viability of implementing such a system. The NASA Glenn Research Center conducted a test program of a 100-lbf (445-N) reaction control engine (RCE) at the Center s Altitude Combustion Stand (ACS), focusing on altitude testing over a wide variety of operational conditions. The ACS facility includes unique propellant conditioning feed systems (PCFS), which allow precise control of propellant inlet conditions to the engine. Engine performance as a result of these inlet conditions was examined extensively during the test program. This paper is a companion to the previous specific impulse testing paper, and discusses the pulsed-mode operation portion of testing, with a focus on minimum impulse bit (MIB) and repeatable pulse performance. The engine successfully demonstrated target MIB performance at all conditions, as well as successful demonstration of repeatable pulse widths. Some anomalous conditions experienced during testing are also discussed, including a double pulse phenomenon, which was not noted in previous test programs for this engine.

  1. FLOYDS Classification of ASASSN-14lo as a Type Ia Supernova Near Peak

    NASA Astrophysics Data System (ADS)

    Arcavi, Iair; Sand, David; McCully, Curtis; Valenti, Stefano; Hosseinzadeh, Griffin; Howell, D. Andrew

    2014-12-01

    We obtained a spectrum of ASASSN-14lo (ATel #6794) on 2014 December 10 (UT) with the robotic FLOYDS instrument mounted on the Faulkes Telescope North. Using Superfit (Howell et al. 2005, ApJ 634, 1190) we find a good fit to the Type Ia SN 1996X around peak at the redshift of the proposed host galaxy (z=0.01993; NED).

  2. Structural Validity of the Professional Development Profile of the LoTi Digital-Age Survey

    ERIC Educational Resources Information Center

    Mehta, Vandhana; Hull, Darrell M.

    2013-01-01

    The present study was used to examine the structural construct validity of the Professional Development Profile of the LoTi Digital-Age Survey, a measure of teacher instructional practices with technology in the classroom. Teacher responses ("N" = 2,840) from across the United States were used to assess factor structure of the instrument using…

  3. Registration of WCL-LO4-Gail lesquerella with improved harvest index

    Technology Transfer Automated Retrieval System (TEKTRAN)

    WCL-LO4-Gail lesquerella (Physaria fendleri L.) germplasm line was publicly released jointly by the USDA, Agricultural Research Service and the University of Arizona, in 2012 as part of the new crops breeding program. The germplasm was developed by mass selection originating from lesquerella germpl...

  4. Ka-im's Gift: A St:lo Legend (with Commentary by the Author).

    ERIC Educational Resources Information Center

    Gardner, Ethel B.

    1988-01-01

    Presents a modern retelling of a St:lo (Coast Salish) legend about the origin of a tribal treasure, the wondrous Sxwaixwe mask. Discusses the legend's origins, the process of transforming essentially oral sources into an accessible contemporary form, and the educational value of storytelling. Contains 13 references. (SV)

  5. Numerical Investigation of LO2 and LCH4 Storage Tanks on the Lunar Surface

    NASA Technical Reports Server (NTRS)

    Moder, Jeff; Barsi, Stephen; Kassemi, Mohammad

    2008-01-01

    Currently NASA is developing technologies to enable human exploration of the lunar surface for duration of up to 210 days. While trade studies are still underway, a cryogenic ascent stage using liquid oxygen (LO2) and liquid methane (LCH4) is being considered for the Altair lunar lander. For a representative Altair cryogenic ascent stage, we present a detailed storage analysis of the LO2 and LCH4 propellant tanks on the lunar surface for durations of up to 210 days. Both the LO2 and LCH4 propellant tanks are assumed to be pressurized with gaseous helium at launch. A two-phase lumped-vapor computational fluid dynamics model has been developed to account for the presence of a noncondensable gas in the ullage. The CFD model is used to simulate the initial pressure response of the propellant tanks while they are subjected to representative heat leak rates on the lunar surface. Once a near stationary state is achieved within the liquid phase, multizone model is used to extrapolate the solution farther in time. For fixed propellant mass and tank size, the long-term pressure response for different helium mass fractions in both the LO2 and LCH4 tanks is examined.

  6. A Simultaneous Discovery: The Case of Johannes Stark and Antonino Lo Surdo

    NASA Astrophysics Data System (ADS)

    Leone, Matteo; Paoletti, Alessandro; Robotti, Nadia

    2004-09-01

    In 1913 the German physicist Johannes Stark (1874 1957) and the Italian physicist Antonino Lo Surdo (1880 1949)discovered virtually simultaneously and independently that hydrogen spectral lines are split into components by an external electric field. Both of their discoveries ensued from studies on the same phenomenon, the Doppler effect in canal rays, but they arose in different theoretical contexts. Stark had been working within the context of the emerging quantum theory, following a research program aimed at studying the effect of an electric field on spectral lines. Lo Surdo had been working within the context of the classical theory, and his was an accidental discovery. Both discoveries, however, played important roles in the history of physics: Stark’s discovery contributed to the establishment of both the old and the new quantum theories; Lo Surdo’s discovery led Antonio Garbasso (1871 1933)to introduce research on the quantum theory into Italian physics. Ironically, soon after their discoveries, both Stark and Lo Surdo rejected developments in modern physics and allied themselves with the political and racial programs of Hitler and Mussolini.

  7. Forwarding techniques for IP fragmented packets in a real 6LoWPAN network.

    PubMed

    Ludovici, Alessandro; Calveras, Anna; Casademont, Jordi

    2011-01-01

    Wireless Sensor Networks (WSNs) are attracting more and more interest since they offer a low-cost solution to the problem of providing a means to deploy large sensor networks in a number of application domains. We believe that a crucial aspect to facilitate WSN diffusion is to make them interoperable with external IP networks. This can be achieved by using the 6LoWPAN protocol stack. 6LoWPAN enables the transmission of IPv6 packets over WSNs based on the IEEE 802.15.4 standard. IPv6 packet size is considerably larger than that of IEEE 802.15.4 data frame. To overcome this problem, 6LoWPAN introduces an adaptation layer between the network and data link layers, allowing IPv6 packets to be adapted to the lower layer constraints. This adaptation layer provides fragmentation and header compression of IP packets. Furthermore, it also can be involved in routing decisions. Depending on which layer is responsible for routing decisions, 6LoWPAN divides routing in two categories: mesh under if the layer concerned is the adaptation layer and route over if it is the network layer. In this paper we analyze different routing solutions (route over, mesh under and enhanced route over) focusing on how they forward fragments. We evaluate their performance in terms of latency and energy consumption when transmitting IP fragmented packets. All the tests have been performed in a real 6LoWPAN implementation. After consideration of the main problems in forwarding of mesh frames in WSN, we propose and analyze a new alternative scheme based on mesh under, which we call controlled mesh under. PMID:22346615

  8. Bio-guided isolation of the cytotoxic terpenoids from the roots of Euphorbia kansui against human normal cell lines L-O2 and GES-1.

    PubMed

    Zhang, Li; Gao, Lan; Li, Zhengjun; Yan, Xiaojing; Yang, Yanjing; Tang, Yuping; Cao, Yudan; Ding, Anwei

    2012-01-01

    The dried roots of Euphorbia kansui (kansui) have been used for centuries in China as a herbal medicine for edema, ascites, and asthma. The 95% ethanol extract showed a significant inhibition of cell proliferation against human normal cell lines L-O2 and GES-1. Bioassay-guided separation of the 95% ethanol extract from the roots of E. kansui led to the isolation of 12 diverse terpenoids whose structures were identified by (1)H, (13)C NMR spectroscopy and ESI-MS as kansuinine A (1), kansuinine B (2), kansuinine C (3), kansuiphorin C (4), 3-O-(2'E,4'Z-decadienoyl)-20-O-acetylingenol (5), 3-O-(2'E,4'Edecadienoyl)-20-O-acetylingenol (6), 3-O-(2'E,4'Z-decadienoyl)-20-deoxyingenol (7), 3-O-benzoyl-20-deoxyingenol (8), 5-O-benzoyl-20-deoxyingenol (9), kansenone (10), epi-kansenone (11), euphol (12). All these 12 terpernoids were evaluated in vitro for cytotoxicity on L-O2 and GES-1 cell lines. Most ingenane-type diterpenoids and 8-ene-7-one triterpenoids (5-11) exhibited a relatively lower IC(50) value; therefore, these compounds had stronger cytotoxicity against human normal cell lines L-O2 and GES-1 with dose-dependent relationships. These results will be significantly helpful to reveal the mechanism of toxicity of kansui and to effectively guide safer clinical application of this herb. PMID:23109850

  9. Bio-Guided Isolation of the Cytotoxic Terpenoids from the Roots of Euphorbia kansui against Human Normal Cell Lines L-O2 and GES-1

    PubMed Central

    Zhang, Li; Gao, Lan; Li, Zhengjun; Yan, Xiaojing; Yang, Yanjing; Tang, Yuping; Cao, Yudan; Ding, Anwei

    2012-01-01

    The dried roots of Euphorbia kansui (kansui) have been used for centuries in China as a herbal medicine for edema, ascites, and asthma. The 95% ethanol extract showed a significant inhibition of cell proliferation against human normal cell lines L-O2 and GES-1. Bioassay-guided separation of the 95% ethanol extract from the roots of E. kansui led to the isolation of 12 diverse terpenoids whose structures were identified by 1H, 13C NMR spectroscopy and ESI-MS as kansuinine A (1), kansuinine B (2), kansuinine C (3), kansuiphorin C (4), 3-O-(2′E,4′Z-decadienoyl)-20-O-acetylingenol (5), 3-O-(2′E,4′Edecadienoyl)-20-O-acetylingenol (6), 3-O-(2′E,4′Z-decadienoyl)-20-deoxyingenol (7), 3-O-benzoyl-20-deoxyingenol (8), 5-O-benzoyl-20-deoxyingenol (9), kansenone (10), epi-kansenone (11), euphol (12). All these 12 terpernoids were evaluated in vitro for cytotoxicity on L-O2 and GES-1 cell lines. Most ingenane-type diterpenoids and 8-ene-7-one triterpenoids (5–11) exhibited a relatively lower IC50 value; therefore, these compounds had stronger cytotoxicity against human normal cell lines L-O2 and GES-1 with dose-dependent relationships. These results will be significantly helpful to reveal the mechanism of toxicity of kansui and to effectively guide safer clinical application of this herb. PMID:23109850

  10. The LO-BaFL method and ALS microarray expression analysis

    PubMed Central

    2012-01-01

    Background Sporadic Amyotrophic Lateral Sclerosis (sALS) is a devastating, complex disease of unknown etiology. We studied this disease with microarray technology to capture as much biological complexity as possible. The Affymetrix-focused BaFL pipeline takes into account problems with probes that arise from physical and biological properties, so we adapted it to handle the long-oligonucleotide probes on our arrays (hence LO-BaFL). The revised method was tested against a validated array experiment and then used in a meta-analysis of peripheral white blood cells from healthy control samples in two experiments. We predicted differentially expressed (DE) genes in our sALS data, combining the results obtained using the TM4 suite of tools with those from the LO-BaFL method. Those predictions were tested using qRT-PCR assays. Results LO-BaFL filtering and DE testing accurately predicted previously validated DE genes in a published experiment on coronary artery disease (CAD). Filtering healthy control data from the sALS and CAD studies with LO-BaFL resulted in highly correlated expression levels across many genes. After bioinformatics analysis, twelve genes from the sALS DE gene list were selected for independent testing using qRT-PCR assays. High-quality RNA from six healthy Control and six sALS samples yielded the predicted differential expression for 7 genes: TARDBP, SKIV2L2, C12orf35, DYNLT1, ACTG1, B2M, and ILKAP. Four of the seven have been previously described in sALS studies, while ACTG1, B2M and ILKAP appear in the context of this disease for the first time. Supplementary material can be accessed at: http://webpages.uncc.edu/~cbaciu/LO-BaFL/supplementary_data.html. Conclusion LO-BaFL predicts DE results that are broadly similar to those of other methods. The small healthy control cohort in the sALS study is a reasonable foundation for predicting DE genes. Modifying the BaFL pipeline allowed us to remove noise and systematic errors, improving the power of this

  11. A1C

    MedlinePlus

    A1C is a blood test for type 2 diabetes and prediabetes. It measures your average blood glucose, or blood sugar, level over the past 3 ... A1C alone or in combination with other diabetes tests to make a diagnosis. They also use the ...

  12. Soft expansion of double-real-virtual corrections to Higgs production at N3LO

    NASA Astrophysics Data System (ADS)

    Anastasiou, Charalampos; Duhr, Claude; Dulat, Falko; Furlan, Elisabetta; Herzog, Franz; Mistlberger, Bernhard

    2015-08-01

    We present methods to compute higher orders in the threshold expansion for the one-loop production of a Higgs boson in association with two partons at hadron colliders. This process contributes to the N3LO Higgs production cross section beyond the soft-virtual approximation. We use reverse unitarity to expand the phase-space integrals in the small kinematic parameters and to reduce the coefficients of the expansion to a small set of master integrals. We describe two methods for the calculation of the master integrals. The first was introduced for the calculation of the soft triple-real radiation relevant to N3LO Higgs production. The second uses a particular factorization of the three body phase-space measure and the knowledge of the scaling properties of the integral itself. Our result is presented as a Laurent expansion in the dimensional regulator, although some of the master integrals are computed to all orders in this parameter.

  13. 100-LBF LO2/LCH4 - Reaction Control Engine Technology Development for Future Space Vehicles

    NASA Technical Reports Server (NTRS)

    Robinson, Philip J.; Veith, Eric M.; Hurlbert, Eric A.; Jimenez, Rafael; Smith, Timothy D.

    2008-01-01

    The National Aeronautics and Space Administration (NASA) has identified liquid oxygen (LO2)/liquid methane (LCH4) propulsion systems as promising options for some future space vehicles. NASA issued a contract to Aerojet to develop a 100-lbf (445 N) LO2/LCH4 Reaction Control Engine (RCE) aimed at reducing the risk of utilizing a cryogenic reaction control system (RCS) on a space vehicle. Aerojet utilized innovative design solutions to develop an RCE that can ignite reliably over a broad range of inlet temperatures, perform short minimum impulse bits (MIB) at small electrical pulse widths (EPW), and produce excellent specific impulse (Isp) across a range of engine mixture ratios (MR). These design innovations also provide a start transient with a benign MR, ensuring good thrust chamber compatibility and long life. In addition, this RCE can successfully operate at MRs associated with main engines, enabling the RCE to provide emergency backup propulsion to minimize vehicle propellant load and overall system mass.

  14. Karhunen-Loève transform for compressive sampling hyperspectral images

    NASA Astrophysics Data System (ADS)

    Liu, Lei; Yan, Jingwen; Zheng, Xianwei; Peng, Hong; Guo, Di; Qu, Xiaobo

    2015-01-01

    Compressed sensing (CS) is a new jointly sampling and compression technology for remote sensing. In hyperspectral imaging, a typical CS method encodes the two-dimensional (2-D) spatial information of each spectral band or encodes the third spectral information simultaneously. However, encoding the spatial information is much easier than encoding the spectral information. Therefore, it is crucial to make use of the spectral information to improve the compression rate on 2-D CS data. We propose to encode the third spectral information with an adaptive Karhunen-Loève transform. With a mathematical proof, we show that interspectral correlations are preserved among 2-D randomly encoded spatial information. This property means that one can compress 2-D CS data effectively with a Karhunen-Loève transform. Experiments demonstrate that the proposed method can better reconstruct both spectral curves and spatial images than traditional compression methods at the bit rates 0 to 1.

  15. Pseudo-scalar Higgs boson production at threshold N^3LO and N^3LL QCD

    NASA Astrophysics Data System (ADS)

    Ahmed, Taushif; Kumar, M. C.; Mathews, Prakash; Rana, Narayan; Ravindran, V.

    2016-06-01

    We present the first results on the production of pseudo-scalar Higgs boson through gluon fusion at the LHC to N^3LO in QCD taking into account only soft-gluon effects. We have used the effective Lagrangian that describes the coupling of the pseudo-scalar Higgs boson with the gluons in the large top quark mass limit. We have used quantities that have recently become available, namely the three-loop pseudo-scalar Higgs boson form factor and the third order universal soft function in QCD to achieve this. Along with the fixed order results, we also present the process dependent resummation coefficient for a threshold resummation to N^3LL in QCD. Phenomenological impact of these threshold N^3LO corrections to pseudo-scalar Higgs boson production at the LHC is presented and their role in the reduction of the renormalization scale dependence is demonstrated.

  16. Dual-Mode Combustor

    NASA Technical Reports Server (NTRS)

    Trefny, Charles J (Inventor); Dippold, Vance F (Inventor)

    2013-01-01

    A new dual-mode ramjet combustor used for operation over a wide flight Mach number range is described. Subsonic combustion mode is usable to lower flight Mach numbers than current dual-mode scramjets. High speed mode is characterized by supersonic combustion in a free-jet that traverses the subsonic combustion chamber to a variable nozzle throat. Although a variable combustor exit aperture is required, the need for fuel staging to accommodate the combustion process is eliminated. Local heating from shock-boundary-layer interactions on combustor walls is also eliminated.

  17. Combination of Vandetanib, Radiotherapy, and Irinotecan in the LoVo Human Colorectal Cancer Xenograft Model

    SciTech Connect

    Wachsberger, Phyllis; Burd, Randy; Ryan, Anderson; Daskalakis, Constantine; Dicker, Adam P.

    2009-11-01

    Purpose: The tumor growth kinetics of the human LoVo colorectal xenograft model was assessed in response to vandetanib, an orally available receptor tyrosine kinase inhibitor, radiotherapy (RT), or irinotecan (CPT-11), as single therapies and in combination. Methods and Materials: LoVo cells were injected subcutaneously into the right hind limb (5x10{sup 6} cells in 100muL phosphate-buffered saline) of athymic NCR NUM mice and tumors were grown to a volume of 200-300 mm{sup 3} before treatment. Vandetanib was administered at 50 mg/kg daily orally for 14 days starting on Day 1. RT was given as three fractions (3x3 Gy) on Days 1, 2, and 3. CPT-11 was given at 15 mg/kg intraperitoneally on Days 1 and 3. Tumor volumes were measured on a daily basis and calculated by measuring tumor diameters with digital calipers in two orthogonal dimensions. Results: All three single treatments (vandetanib, CPT-11, and radiation) significantly slowed LoVo colorectal tumor growth. Vandetanib significantly increased the antitumor effects of CPT-11 and radiation when given in combination with either of these treatments. These treatment combinations resulted in a slow tumor growth rate during the 2 weeks of vandetanib administration. The triple combination of vandetanib, CPT-11, and radiation produced the most marked improvement in response as observed by measurable shrinkage of tumors during the first week of treatment. Conclusions: The tumor growth delay kinetics observed in this study of the LoVo colorectal model suggest concurrent and sustained post-sequencing of vandetanib with cytotoxic therapy may be beneficial in tumors of this type.

  18. Two different periods present in the binary nucleus of the planetary nebula LoTr5

    NASA Astrophysics Data System (ADS)

    Kuczawska, Ewa; Mikolajewski, M.

    1993-10-01

    We present new photoelectric UBV observations of IN Com -- the binary nucleus of the planetary nebula LoTr5, carried out in April 1993 with the double beam photometer at Mt. Suhora Observatory. Low-amplitude variations were detected with a period of about 5.d92, in agreement with the results of Noskova (1989) and Bond and Livio (1990), but also higher frequency variability was discovered. A preliminary ephemeris is given. We speculate on the origin of the observed variabilities.

  19. A network access control framework for 6LoWPAN networks.

    PubMed

    Oliveira, Luís M L; Rodrigues, Joel J P C; de Sousa, Amaro F; Lloret, Jaime

    2013-01-01

    Low power over wireless personal area networks (LoWPAN), in particular wireless sensor networks, represent an emerging technology with high potential to be employed in critical situations like security surveillance, battlefields, smart-grids, and in e-health applications. The support of security services in LoWPAN is considered a challenge. First, this type of networks is usually deployed in unattended environments, making them vulnerable to security attacks. Second, the constraints inherent to LoWPAN, such as scarce resources and limited battery capacity, impose a careful planning on how and where the security services should be deployed. Besides protecting the network from some well-known threats, it is important that security mechanisms be able to withstand attacks that have not been identified before. One way of reaching this goal is to control, at the network access level, which nodes can be attached to the network and to enforce their security compliance. This paper presents a network access security framework that can be used to control the nodes that have access to the network, based on administrative approval, and to enforce security compliance to the authorized nodes. PMID:23334610

  20. Ultra-low-voltage CMOS-based current bleeding mixer with high LO-RF isolation.

    PubMed

    Tan, Gim Heng; Sidek, Roslina Mohd; Ramiah, Harikrishnan; Chong, Wei Keat; Lioe, De Xing

    2014-01-01

    This journal presents an ultra-low-voltage current bleeding mixer with high LO-RF port-to-port isolation, implemented on 0.13 μm standard CMOS technology for ZigBee application. The architecture compliments a modified current bleeding topology, consisting of NMOS-based current bleeding transistor, PMOS-based switching stage, and integrated inductors achieving low-voltage operation and high LO-RF isolation. The mixer exhibits a conversion gain of 7.5 dB at the radio frequency (RF) of 2.4 GHz, an input third-order intercept point (IIP3) of 1 dBm, and a LO-RF isolation measured to 60 dB. The DC power consumption is 572 µW at supply voltage of 0.45 V, while consuming a chip area of 0.97 × 0.88 mm(2). PMID:25197694

  1. Stella Surface Imaging of LO Pegasi via Light-Curve Inversion

    NASA Astrophysics Data System (ADS)

    Miller, Jessie; Richard, Andrea; Harmon, Robert

    2009-10-01

    The purpose of this research was to map the starspots on LO Pegasi (HIP 106231), a K8 main-sequence star, in order to create an image of the star's photosphere. CCD images of LO Pegasi were taken during May, June, and July 2009 through B, V, R, and I photometric filters using a 0.2-m Meade Instruments LX200 Schmidt-Cassegrain telescope and Santa Barbara Instruments Group ST-8XE CCD camera at Perkins Observatory. Differential aperture photometry was performed on the images so as to create light curves in the form of plots of intensity vs. rotational phase. The lightcurves were processed via the Light-Curve Inversion (LI) algorithm. This algorithm creates a reconstructed image of the star's surface showing the locations of starspots. The locations of the spots visible on the 2009 are at lower latitudes than those deduced from the 2008 light curves. In addition, overall dimming observed of LO Pegasi since 2008 implies that there is a spot on the visible pole. Since a polar spot does not modulate the rotational light curve, it is not reproduced in our images.

  2. Fast Calcium Imaging with Optical Sectioning via HiLo Microscopy.

    PubMed

    Lauterbach, Marcel A; Ronzitti, Emiliano; Sternberg, Jenna R; Wyart, Claire; Emiliani, Valentina

    2015-01-01

    Imaging intracellular calcium concentration via reporters that change their fluorescence properties upon binding of calcium, referred to as calcium imaging, has revolutionized our way to probe neuronal activity non-invasively. To reach neurons densely located deep in the tissue, optical sectioning at high rate of acquisition is necessary but difficult to achieve in a cost effective manner. Here we implement an accessible solution relying on HiLo microscopy to provide robust optical sectioning with a high frame rate in vivo. We show that large calcium signals can be recorded from dense neuronal populations at high acquisition rates. We quantify the optical sectioning capabilities and demonstrate the benefits of HiLo microscopy compared to wide-field microscopy for calcium imaging and 3D reconstruction. We apply HiLo microscopy to functional calcium imaging at 100 frames per second deep in biological tissues. This approach enables us to discriminate neuronal activity of motor neurons from different depths in the spinal cord of zebrafish embryos. We observe distinct time courses of calcium signals in somata and axons. We show that our method enables to remove large fluctuations of the background fluorescence. All together our setup can be implemented to provide efficient optical sectioning in vivo at low cost on a wide range of existing microscopes. PMID:26625116

  3. Fast Calcium Imaging with Optical Sectioning via HiLo Microscopy

    PubMed Central

    Sternberg, Jenna R.; Wyart, Claire; Emiliani, Valentina

    2015-01-01

    Imaging intracellular calcium concentration via reporters that change their fluorescence properties upon binding of calcium, referred to as calcium imaging, has revolutionized our way to probe neuronal activity non-invasively. To reach neurons densely located deep in the tissue, optical sectioning at high rate of acquisition is necessary but difficult to achieve in a cost effective manner. Here we implement an accessible solution relying on HiLo microscopy to provide robust optical sectioning with a high frame rate in vivo. We show that large calcium signals can be recorded from dense neuronal populations at high acquisition rates. We quantify the optical sectioning capabilities and demonstrate the benefits of HiLo microscopy compared to wide-field microscopy for calcium imaging and 3D reconstruction. We apply HiLo microscopy to functional calcium imaging at 100 frames per second deep in biological tissues. This approach enables us to discriminate neuronal activity of motor neurons from different depths in the spinal cord of zebrafish embryos. We observe distinct time courses of calcium signals in somata and axons. We show that our method enables to remove large fluctuations of the background fluorescence. All together our setup can be implemented to provide efficient optical sectioning in vivo at low cost on a wide range of existing microscopes. PMID:26625116

  4. Characterization of secreted proteins in HepG2 and LO2 cells by Raman spectroscopy

    NASA Astrophysics Data System (ADS)

    Lin, Juqiang; Ruan, Qiuyong; Liao, Fadian; Lin, Jinyong; Huang, Zufang; Liu, Nenrong; Chen, Rong

    2014-11-01

    Secreted proteins, the promising source of biomarkers for early detection and diagnosis of cancer, have received considerable attention. Raman spectroscopy and principal component analysis (PCA) were used to characterize the secreted proteins collected from the cell cultures of human hepatoma cell line HepG2 and normal human liver cell line LO2 in this paper. We found the major difference of secreted proteins Raman spectra between HepG2 and LO2 cells were in the range of 1200cm-1-1800cm-1. Compared with LO2 cells, some significant changes based on secondary structure of secreted proteins in HepG2 cells were observed, including the increase in the relative intensity of the band at 1004cm-1, 1445cm-1, 1674cm-1 and the decrease at 1074cm-1. These variations of Raman bands indicated that the species and conformation of secreted proteins in HepG2 cells changed. The measured Raman spectra of the two groups were separated into two distinct clusters with no overlap and high specificity and sensitivity by PCA. These results show that the combination of Raman spectroscopy and PCA analysis may be a powerful tool for distinguishing the secreted proteins between human hepatoma cells and normal human liver cells, provide a new thought to analyze the secreted proteins from cancer cells and find a novel cancer biomarker.

  5. Nature of the X(5568) — A critical Laplace sum rule analysis at N2LO

    NASA Astrophysics Data System (ADS)

    Albuquerque, R.; Narison, S.; Rabemananjara, A.; Rabetiarivony, D.

    2016-06-01

    We scrutinize recent QCD spectral sum rules (QSSR) results to lowest order (LO) predicting the masses of the BK molecule and (su)(bd¯) four-quark states. We improve these results by adding NLO and N2LO corrections to the PT contributions giving a more precise meaning on the b-quark mass definition used in the analysis. We extract our optimal predictions using Laplace sum rule (LSR) within the standard stability criteria versus the changes of the external free parameters (τ-sum rule variable, tc continuum threshold and subtraction constant μ). The smallness of the higher order PT corrections justifies (a posteriori) the LO order results ⊕ the uses of the ambiguous heavy quark mass to that order. However, our predicted spectra in the range (5173 ˜ 5226) MeV, summarized in Table 7, for exotic hadrons built with four different flavors (buds), do not support some previous interpretations of the D0 candidate,1 X(5568), as a pure molecule or a four-quark state. If experimentally confirmed, it could result from their mixing with an angle: sin 2𝜃 ≈ 0.15. One can also scan the region (2327 ˜ 2444) MeV (where the Ds0∗(2317) might be a good candidate) and the one (5173 ˜ 5226) MeV for detecting these (cuds) and (buds) unmixed exotic hadrons (if any) via, eventually, their radiative or π+hadrons decays.

  6. A Network Access Control Framework for 6LoWPAN Networks

    PubMed Central

    Oliveira, Luís M. L.; Rodrigues, Joel J. P. C.; de Sousa, Amaro F.; Lloret, Jaime

    2013-01-01

    Low power over wireless personal area networks (LoWPAN), in particular wireless sensor networks, represent an emerging technology with high potential to be employed in critical situations like security surveillance, battlefields, smart-grids, and in e-health applications. The support of security services in LoWPAN is considered a challenge. First, this type of networks is usually deployed in unattended environments, making them vulnerable to security attacks. Second, the constraints inherent to LoWPAN, such as scarce resources and limited battery capacity, impose a careful planning on how and where the security services should be deployed. Besides protecting the network from some well-known threats, it is important that security mechanisms be able to withstand attacks that have not been identified before. One way of reaching this goal is to control, at the network access level, which nodes can be attached to the network and to enforce their security compliance. This paper presents a network access security framework that can be used to control the nodes that have access to the network, based on administrative approval, and to enforce security compliance to the authorized nodes. PMID:23334610

  7. Effects of ADMA on gene expression and metabolism in serum-starved LoVo cells.

    PubMed

    Zheng, Ningning; Wang, Ke; He, Jiaojiao; Qiu, Yunping; Xie, Guoxiang; Su, Mingming; Jia, Wei; Li, Houkai

    2016-01-01

    Serum starvation is a typical way for inducing tumor cell apoptosis and stress. Asymmetric dimethylarginine (ADMA) is an endogenous metabolite. Our previous study reveals the plasma ADMA level is elevated in colon cancer patients, which can attenuate serum starvation-induced apoptosis in LoVo cells. In current study, we evaluated the effects of ADMA on gene expression and metabolism in serum-starved LoVo cells with gene microarray and metabolomic approaches. Our results indicated that 96 h serum starvation induced comprehensive alterations at transcriptional level, and most of them were restored by ADMA. The main signaling pathways induced by serum starvation included cancers-related pathways, pathways in cell death, apoptosis, and cell cycle etc. Meanwhile, the metabolomic data showed serum-starved cells were clearly separated with control cells, but not with ADMA-treated cells in PCA model. The identified differential metabolites indicated serum starvation significantly suppressed TCA cycle, altered glucose and fatty acids metabolism, as well as nucleic acids metabolism. However, very few differential metabolites were identified between ADMA and serum-starved cells. In summary, our current results indicated serum starvation profoundly altered the gene expression and metabolism of LoVo cells, whereas ADMA could restore most of the changes at transcriptional level, but not at metabolic level. PMID:27180883

  8. Effects of ADMA on gene expression and metabolism in serum-starved LoVo cells

    PubMed Central

    Zheng, Ningning; Wang, Ke; He, Jiaojiao; Qiu, Yunping; Xie, Guoxiang; Su, Mingming; Jia, Wei; Li, Houkai

    2016-01-01

    Serum starvation is a typical way for inducing tumor cell apoptosis and stress. Asymmetric dimethylarginine (ADMA) is an endogenous metabolite. Our previous study reveals the plasma ADMA level is elevated in colon cancer patients, which can attenuate serum starvation-induced apoptosis in LoVo cells. In current study, we evaluated the effects of ADMA on gene expression and metabolism in serum-starved LoVo cells with gene microarray and metabolomic approaches. Our results indicated that 96 h serum starvation induced comprehensive alterations at transcriptional level, and most of them were restored by ADMA. The main signaling pathways induced by serum starvation included cancers-related pathways, pathways in cell death, apoptosis, and cell cycle etc. Meanwhile, the metabolomic data showed serum-starved cells were clearly separated with control cells, but not with ADMA-treated cells in PCA model. The identified differential metabolites indicated serum starvation significantly suppressed TCA cycle, altered glucose and fatty acids metabolism, as well as nucleic acids metabolism. However, very few differential metabolites were identified between ADMA and serum-starved cells. In summary, our current results indicated serum starvation profoundly altered the gene expression and metabolism of LoVo cells, whereas ADMA could restore most of the changes at transcriptional level, but not at metabolic level. PMID:27180883

  9. Achievement of Bevalac rapid mode switching

    SciTech Connect

    Lothrop, F.; Stevenson, R.; Miller, R.; Alonso, J.

    1985-05-01

    Rapid changes of ion, intensity, beam line, and output energy between two modes have been achieved. The techniques for switching among the Bevalac's several injectors are described. Energy level limits at the output (for q/A = 1/2) are 470 to 2100 MeV/n (high power) or 50 to 1050 MeV/n (low power). Depending on specific field value differences, the total time required for a mode change is less than one minute. This mode of operation greatly improves program efficiency in interleaving medical and nuclear science programs at the Bevalac.

  10. A1C Test

    MedlinePlus

    ... to minimize the complications caused by chronically elevated glucose levels, such as progressive damage to body organs like the kidneys, eyes, cardiovascular system, and nerves. The A1c test result ...

  11. Tearing Modes in Tokamaks

    NASA Astrophysics Data System (ADS)

    White, R. B.

    2008-05-01

    This lecture gives a basic introduction to magnetic £elds, magnetic surface destruction, toroidal equilibrium and tearing modes in a tokamak, including the linear and nonlinear development of these modes and their modi£cation by current drive and bootstrap current, and sawtooth oscillations and disruptions.

  12. A waveguide-typed plasmonic mode converter.

    PubMed

    Park, Hae-Ryeong; Park, Jong-Moon; Kim, Min-Su; Lee, Myung-Hyun

    2012-08-13

    Waveguide-typed plasmonic mode converters (WPMCs) at a wavelength of 1.55 μm are presented. The WPMC is composed of an insulator-metal-insulator waveguide (IMI-W), a 1st reversely tapered insulator-metal-insulator-metal-insulator waveguide (RT-IMIMI-W), an insulator-metal-insulator-metal-insulator waveguide (IMIMI-W), a 2nd RT-IMIMI-W with lateral silver mirrors (LSMs), and a metal-insulator-metal waveguide (MIM-W) in series. The mode sizes for the IMI-W, IMIMI-W, and MIM-W via the IMIMI-W with LSMs were not only calculated using a finite element method but were also experimentally measured. The input mode size of 10.3 μm × 10.3 μm from a polarization-maintaining single-mode fiber was squeezed to the mode size of ~2.9 μm × 2.9 μm in measurement by converting an s0 mode to an Sa0 mode via an Ss0 mode. The WPMC may be potentially useful for bridging micro- to nano-plasmonic integrated circuits. PMID:23038504

  13. Mode decomposition evolution equations

    PubMed Central

    Wang, Yang; Wei, Guo-Wei; Yang, Siyang

    2011-01-01

    Partial differential equation (PDE) based methods have become some of the most powerful tools for exploring the fundamental problems in signal processing, image processing, computer vision, machine vision and artificial intelligence in the past two decades. The advantages of PDE based approaches are that they can be made fully automatic, robust for the analysis of images, videos and high dimensional data. A fundamental question is whether one can use PDEs to perform all the basic tasks in the image processing. If one can devise PDEs to perform full-scale mode decomposition for signals and images, the modes thus generated would be very useful for secondary processing to meet the needs in various types of signal and image processing. Despite of great progress in PDE based image analysis in the past two decades, the basic roles of PDEs in image/signal analysis are only limited to PDE based low-pass filters, and their applications to noise removal, edge detection, segmentation, etc. At present, it is not clear how to construct PDE based methods for full-scale mode decomposition. The above-mentioned limitation of most current PDE based image/signal processing methods is addressed in the proposed work, in which we introduce a family of mode decomposition evolution equations (MoDEEs) for a vast variety of applications. The MoDEEs are constructed as an extension of a PDE based high-pass filter (Europhys. Lett., 59(6): 814, 2002) by using arbitrarily high order PDE based low-pass filters introduced by Wei (IEEE Signal Process. Lett., 6(7): 165, 1999). The use of arbitrarily high order PDEs is essential to the frequency localization in the mode decomposition. Similar to the wavelet transform, the present MoDEEs have a controllable time-frequency localization and allow a perfect reconstruction of the original function. Therefore, the MoDEE operation is also called a PDE transform. However, modes generated from the present approach are in the spatial or time domain and can be

  14. Zero-mode waveguides

    DOEpatents

    Levene, Michael J.; Korlach, Jonas; Turner, Stephen W.; Craighead, Harold G.; Webb, Watt W.

    2007-02-20

    The present invention is directed to a method and an apparatus for analysis of an analyte. The method involves providing a zero-mode waveguide which includes a cladding surrounding a core where the cladding is configured to preclude propagation of electromagnetic energy of a frequency less than a cutoff frequency longitudinally through the core of the zero-mode waveguide. The analyte is positioned in the core of the zero-mode waveguide and is then subjected, in the core of the zero-mode waveguide, to activating electromagnetic radiation of a frequency less than the cut-off frequency under conditions effective to permit analysis of the analyte in an effective observation volume which is more compact than if the analysis were carried out in the absence of the zero-mode waveguide.

  15. Excursions through KK modes

    NASA Astrophysics Data System (ADS)

    Furuuchi, Kazuyuki

    2016-07-01

    In this article we study Kaluza-Klein (KK) dimensional reduction of massive Abelian gauge theories with charged matter fields on a circle. Since local gauge transformations change position dependence of the charged fields, the decomposition of the charged matter fields into KK modes is gauge dependent. While whole KK mass spectrum is independent of the gauge choice, the mode number depends on the gauge. The masses of the KK modes also depend on the field value of the zero-mode of the extra dimensional component of the gauge field. In particular, one of the KK modes in the KK tower of each massless 5D charged field becomes massless at particular values of the extra-dimensional component of the gauge field. When the extra-dimensional component of the gauge field is identified with the inflaton, this structure leads to recursive cosmological particle productions.

  16. Sulfotransferase 4A1.

    PubMed

    Minchin, Rodney F; Lewis, Aaron; Mitchell, Deanne; Kadlubar, Fred F; McManus, Michael E

    2008-01-01

    In this review, we highlight the physical and enzymatic properties of the novel human sulfotransferase, SULT4A1. The gene is most highly expressed in selective regions of the brain, although work to date has failed to identify any specific endogenous substrate for the enzyme. SULT4A1 shares low homology with other human sulfotransferases. Nevertheless, it is highly conserved between species. Despite the low homology, it is structurally very similar to other cytosolic sulfotransferases with a conserved substrate binding domain, dimerization site and partial cofactor binding sites. However, the catalytic cavity is much smaller, and it has been suggested that the cofactor may not be accommodated within it. A recent link between variability in the 5'UTR of the SULT4A1 gene and schizophrenia has heightened interest in the endogenous function of the enzyme and its possible role in human disease. PMID:18248844

  17. G-LoSA: An efficient computational tool for local structure-centric biological studies and drug design.

    PubMed

    Lee, Hui Sun; Im, Wonpil

    2016-04-01

    Molecular recognition by protein mostly occurs in a local region on the protein surface. Thus, an efficient computational method for accurate characterization of protein local structural conservation is necessary to better understand biology and drug design. We present a novel local structure alignment tool, G-LoSA. G-LoSA aligns protein local structures in a sequence order independent way and provides a GA-score, a chemical feature-based and size-independent structure similarity score. Our benchmark validation shows the robust performance of G-LoSA to the local structures of diverse sizes and characteristics, demonstrating its universal applicability to local structure-centric comparative biology studies. In particular, G-LoSA is highly effective in detecting conserved local regions on the entire surface of a given protein. In addition, the applications of G-LoSA to identifying template ligands and predicting ligand and protein binding sites illustrate its strong potential for computer-aided drug design. We hope that G-LoSA can be a useful computational method for exploring interesting biological problems through large-scale comparison of protein local structures and facilitating drug discovery research and development. G-LoSA is freely available to academic users at http://im.compbio.ku.edu/GLoSA/. PMID:26813336

  18. Ultra-broadband IF/LO system of NTU W-band interferometer array

    NASA Astrophysics Data System (ADS)

    Teng, Hsiao-Feng; Wu, Jing-Cheng; Li, Huan-Hsin; Chiueh, Tzi-Hong; Niu, Dou-Chih; Hu, Robert

    2010-07-01

    NTU-Array is designed for W-band (78-113Ghz) interferometric observations of Sunyaev-Zeldovich effects. The first phase operation of the telescope with 6 receivers had its first light in 2008 with single-polarization and half the full bandwidth. The second-phase operation of NTU-Array in Nevada will begin the dual-polarization, full-band observation in 2010. One-bit sampling at 18Ghz and digital correlation are in use in this telescope. Due to the ultra broadband coverage, the IF system divides the 35GHz full-band into four 8.7GHz sub-bands. The first stage of IF module containing a 35GHz broadband amplifier with fairly flat-gain performance over 25db gain divides the first-stage IF into two outputs. The 2nd-stage IF module further divides the two input IF signals and down-converts them to four basebands of DC-8.7Ghz. An LO module with 8.7Ghz input is to generate outputs with x2, x3 and x9 harmonics for the down-conversion. The Walsh function is injected into the x9 LO via an IQ mixer. Each IF baseband is transmitted through an optical link to the 18Ghz, 1-bit sampling ADC located in the control room. The analog optical link contains a driver and equalizer to compensate for the path loss. Considering the limited size of the telescope mount, the entire IF/LO system of each receiver has a compact size about 20cm cubed. This physical size can be further reduced to fit the future 19-pixel-receiver upgrade of NTU-Array

  19. Higgs boson gluon-fusion production beyond threshold in N3LO QCD

    SciTech Connect

    Anastasiou, Charalampos; Duhr, Claude; Dulat, Falko; Furlan, Elisabetta; Gehrmann, Thomas; Herzog, Franz; Mistlberger, Bernhard

    2015-03-18

    In this study, we compute the gluon fusion Higgs boson cross-section at N3LO through the second term in the threshold expansion. This calculation constitutes a major milestone towards the full N3LO cross section. Our result has the best formal accuracy in the threshold expansion currently available, and includes contributions from collinear regions besides subleading corrections from soft and hard regions, as well as certain logarithmically enhanced contributions for general kinematics. We use our results to perform a critical appraisal of the validity of the threshold approximation at N3LO in perturbative QCD.

  20. Potential NRQCD for unequal masses and the B c spectrum at N3LO

    NASA Astrophysics Data System (ADS)

    Peset, Clara; Pineda, Antonio; Stahlhofen, Maximilian

    2016-05-01

    We determine the 1 /m and 1 /m 2 spin-independent heavy quarkonium potentials in the unequal mass case with {O} ( α 3) and {O} ( α 2) accuracy, respectively. We discuss in detail different methods to calculate the potentials, and show the equivalence among them. In particular we obtain, for the first time, the manifestly gauge invariant 1 /m and 1 /m 2 potentials in terms of Wilson loops with next-to-leading order (NLO) precision. As an application of our results we derive the theoretical expression for the B c spectrum in the weak-coupling limit through next-to-next-to-next-to-leading order (N3LO).

  1. Surface Maps of LO Pegasi May-July 2011 Generated via BVRI Light Curve Inversion

    NASA Astrophysics Data System (ADS)

    Harmon, Robert O.; Johns Vidaurri, P.; Krug, S.

    2012-01-01

    The young solar analog LO Pegasi is a rapidly rotating (P ≈ 10.2 hr) K8 main sequence star known to exhibit large cool spots on its surface. We present surface maps based on BVRI photometry obtained at Perkins Observatory from May-July 2011 and inverted with an algorithm which makes no a priori assumptions regarding the number of spots or their shapes, and compare the results to images generated from 2006-2010. This work was supported by the NSF REU Program.

  2. Hilbert-space Karhunen-Loève transform with application to image analysis.

    PubMed

    Levy, A; Rubinstein, J

    1999-01-01

    A generalization of the Karhunen-Loève (KL) transform to Hilbert spaces is developed. It allows one to find the best low-dimensional approximation of an ensemble of images with respect to a variety of distance functions other than the traditional mean square error (L2 norm). A simple and intuitive characterization of the family of Hilbert norms in finite-dimensional spaces leads to an algorithm for calculating the Hilbert-KL expansion. KL approximations of ensembles of objects and faces optimized with respect to a norm based on the modulation transfer function of the human visual system are compared with the standard L2 approximations. PMID:9919692

  3. Mode II fatigue crack propagation.

    NASA Technical Reports Server (NTRS)

    Roberts, R.; Kibler, J. J.

    1971-01-01

    Fatigue crack propagation rates were obtained for 2024-T3 bare aluminum plates subjected to in-plane, mode I, extensional loads and transverse, mode II, bending loads. These results were compared to the results of Iida and Kobayashi for in-plane mode I-mode II extensional loads. The engineering significance of mode I-mode II fatigue crack growth is considered in view of the present results. A fatigue crack growth equation for handling mode I-mode II fatigue crack growth rates from existing mode I data is also discussed.

  4. Single mode thermal emission.

    PubMed

    Fohrmann, Lena Simone; Petrov, Alexander Yu; Lang, Slawa; Jalas, Dirk; Krauss, Thomas F; Eich, Manfred

    2015-10-19

    We report on the properties of a thermal emitter which radiates into a single mode waveguide. We show that the maximal power of thermal radiation into a propagating single mode is limited only by the temperature of the thermal emitter and does not depend on other parameters of the waveguide. Furthermore, we show that the power of the thermal emitter cannot be increased by resonant coupling. For a given temperature, the enhancement of the total emitted power is only possible if the number of excited modes is increased. Either a narrowband or a broadband thermal excitation of the mode is possible, depending on the properties of the emitter. We finally discuss an example system, namely a thermal source for silicon photonics. PMID:26480429

  5. Supersymmetric mode converters

    NASA Astrophysics Data System (ADS)

    Heinrich, Matthias; Miri, Mohammad-Ali; Stützer, Simon; Nolte, Stefan; Szameit, Alexander; Christodoulides, Demetrios N.

    2015-08-01

    In recent years, the ever-increasing demand for high-capacity transmission systems has driven remarkable advances in technologies that encode information on an optical signal. Mode-division multiplexing makes use of individual modes supported by an optical waveguide as mutually orthogonal channels. The key requirement in this approach is the capability to selectively populate and extract specific modes. Optical supersymmetry (SUSY) has recently been proposed as a particularly elegant way to resolve this design challenge in a manner that is inherently scalable, and at the same time maintains compatibility with existing multiplexing strategies. Supersymmetric partners of multimode waveguides are characterized by the fact that they share all of their effective indices with the original waveguide. The crucial exception is the fundamental mode, which is absent from the spectrum of the partner waveguide. Here, we demonstrate experimentally how this global phase-matching property can be exploited for efficient mode conversion. Multimode structures and their superpartners are experimentally realized in coupled networks of femtosecond laser-written waveguides, and the corresponding light dynamics are directly observed by means of fluorescence microscopy. We show that SUSY transformations can readily facilitate the removal of the fundamental mode from multimode optical structures. In turn, hierarchical sequences of such SUSY partners naturally implement the conversion between modes of adjacent order. Our experiments illustrate just one of the many possibilities of how SUSY may serve as a building block for integrated mode-division multiplexing arrangements. Supersymmetric notions may enrich and expand integrated photonics by versatile optical components and desirable, yet previously unattainable, functionalities.

  6. Some Candidates for Solar Gravity Modes

    NASA Astrophysics Data System (ADS)

    Thomson, David J.

    2015-04-01

    Since the accidental discovery of solar modes in space (Thomson,Maclennan, and Lanzerotti, Nature, 1995) work has continued and there are now a few candidates for identified solar gravity modes using charged particles and interplanetary magnetic field data. Contrary to initial expectations, there is a preference for higher-l modes, typically l = 2 to 5.Second, different frequencies are expected at ACE (at L1) and Ulysses, in an almost sidereal solar-polar orbit. Given a candidate detection at ACE where signal-to-noise ratios are higher, one can then shift frequencies by ±32m nHz and test for agreement at Ulysses.Third, the 7.5 degree inclination of the ecliptic on the solar equator splits odd-parity modes at ACE by32 nHz. The two sub-singlets have a defined phase relation that can be used as a further check on parity. Two such modes are G2,-1 at 296.195 uHz and G3,-2 at 296.887 uHz. Both have all 2l+1 singlets detected on both ACE and Ulysses.The 11 singlets of the G5,-1 mode are also all detected above the 99% level. The mode has a center frequency of 383.812 uHz with a1 ≈ 918 nHz.

  7. Cryptanalysis of the Hwang-Lo-Lin Scheme Based on an ID-Based Cryptosystem and Its Improvement

    NASA Astrophysics Data System (ADS)

    Park, Haeryong; Chun, Kilsoo; Ahn, Seungho

    Hwang-Lo-Lin proposed a user identification scheme [3] based on the Maurer-Yacobi scheme [6] that is suitable for application to the mobile environment. Hwang-Lo-Lin argued that their scheme is secure against any attack. Against the Hwang-Lo-Lin argument, Liu-Horng-Liu showed that the Hwang-Lo-Lin scheme is insecure against a Liu-Horng-Liu attack mounted by an eavesdrop attacker. However, Liu-Horng-Liu did not propose any improved version of the original identification scheme which is still secure against the Liu-Horng-Liu attack. In this paper, we propose an identification scheme that can solve this problem and a non-interactive public key distribution scheme also.

  8. THE EXTRAORDINARY MID-INFRARED SPECTRAL PROPERTIES OF FeLoBAL QUASARS

    SciTech Connect

    Farrah, D.; Urrutia, T.; Lacy, M.; Lebouteiller, V.; Spoon, H. W. W.; Bernard-Salas, J.; Houck, J.; Connolly, N.; Afonso, J.; Connolly, B.

    2010-07-10

    We present mid-infrared (mid-IR) spectra of six FeLoBAL quasi-stellar objects (QSOs) at 1 < z < 1.8, taken with the Spitzer Space Telescope. The spectra span a range of shapes, from hot dust-dominated active galactic nuclei (AGNs) with silicate emission at 9.7 {mu}m to moderately obscured starbursts with strong polycyclic aromatic hydrocarbon (PAH) emission. The spectrum of one object, SDSS 1214-0001, shows the most prominent PAHs yet seen in any QSO at any redshift, implying that the starburst dominates the mid-IR emission with an associated star formation rate on the order of 2700 M{sub sun} yr{sup -1}. With the caveats that our sample is small and not robustly selected, we combine our mid-IR spectral diagnostics with previous observations to propose that FeLoBAL QSOs are at least largely comprised of systems in which (1) a merger-driven starburst is ending, (2) a luminous AGN is in the last stages of burning through its surrounding dust, and (3) we may be viewing over a restricted line-of-sight range.

  9. Pavement crack detection combining non-negative feature with fast LoG in complex scene

    NASA Astrophysics Data System (ADS)

    Wang, Wanli; Zhang, Xiuhua; Hong, Hanyu

    2015-12-01

    Pavement crack detection is affected by much interference in the realistic situation, such as the shadow, road sign, oil stain, salt and pepper noise etc. Due to these unfavorable factors, the exist crack detection methods are difficult to distinguish the crack from background correctly. How to extract crack information effectively is the key problem to the road crack detection system. To solve this problem, a novel method for pavement crack detection based on combining non-negative feature with fast LoG is proposed. The two key novelties and benefits of this new approach are that 1) using image pixel gray value compensation to acquisit uniform image, and 2) combining non-negative feature with fast LoG to extract crack information. The image preprocessing results demonstrate that the method is indeed able to homogenize the crack image with more accurately compared to existing methods. A large number of experimental results demonstrate the proposed approach can detect the crack regions more correctly compared with traditional methods.

  10. LO Peg: surface differential rotation, flares, and spot-topographic evolution

    NASA Astrophysics Data System (ADS)

    Karmakar, Subhajeet; Pandey, J. C.; Savanov, I. S.; Taş, G.; Pandey, S. B.; Misra, K.; Joshi, S.; Dmitrienko, E. S.; Sakamoto, T.; Gehrels, N.; Okajima, T.

    2016-07-01

    Using the wealth of ˜24 yr multiband data, we present an in-depth study of the star-spot cycles, surface differential rotations (SDR), optical flares, evolution of star-spot distributions, and coronal activities on the surface of young, single, main-sequence, ultrafast rotator LO Peg. From the long-term V-band photometry, we derive rotational period of LO Peg to be 0.4231 ± 0.0001 d. Using the seasonal variations on the rotational period, the SDR pattern is investigated, and shows a solar-like pattern of SDR. A cyclic pattern with period of ˜2.7 yr appears to be present in rotational period variation. During the observations, 20 optical flares are detected with a flare frequency of ˜1 flare per two days and with flare energy of ˜1031-34 erg. The surface coverage of cool spots is found to be in the range of ˜9-26 per cent. It appears that the high- and low-latitude spots are interchanging their positions. Quasi-simultaneous observations in X-ray, UV, and optical photometric bands show a signature of an excess of X-ray and UV activities in spotted regions.

  11. Non-linear analysis of PESA-Lo electrostatic analyzer data and solar wind temperature anisotropies

    NASA Astrophysics Data System (ADS)

    Djordjevic, B. Z.; Maruca, B.; Bale, S. D.; Wilson, L. B., III; Larson, D. E.

    2015-12-01

    In this study, non-linear fitting techniques are applied to ion measurements from the Wind spacecraft's PESA-Lo electrostatic analyzer. Previous studies have relied primarily on moments-analyses, which, although satisfactory for simple distributions and density calculations, often return unreasonable values for higher order moments (e.g., temperature) and fail to account for non-thermal effects (e.g., temperature anisotropy and beams) and multiple ion-species. A Levenberg-Marquadt non-linear algorithm is applied to the PESA-Lo data in order to calculate the characteristic parameters of the proton, alpha-particle, and beam distributions. This analysis is augmented with calibration data from the WIND Faraday cups and magnetic-field data from WIND/MFI. Preliminary results from this non-linear analysis indicate that it indeed provides higher-quality ion parameters than the existing moments-analysis. When this analysis is complete, the set of bulk-parameter values will be suitable for studies of microinstabilities in the solar wind and of possible correlation between magnetic field fluctuations and non-thermal properties of the ion distributions. Applications of thermodynamic principles, such as the Boltzmann H-theorem, will allow for further characterization of the non-thermal properties of the solar wind.

  12. Soft Expansion of Double-Real-Virtual Corrections to Higgs Production at N$^3$LO

    DOE PAGESBeta

    Anastasiou, Charalampos; Duhr, Claude; Dulat, Falko; Furlan, Elisabetta; Herzog, Franz; Mistlberger, Bernhard

    2015-05-15

    We present methods to compute higher orders in the threshold expansion for the one-loop production of a Higgs boson in association with two partons at hadron colliders. This process contributes to the N3LO Higgs production cross section beyond the soft-virtual approximation. We use reverse unitarity to expand the phase-space integrals in the small kinematic parameters and to reduce the coefficients of the expansion to a small set of master integrals. We describe two methods for the calculation of the master integrals. The first was introduced for the calculation of the soft triple-real radiation relevant to N3LO Higgs production. The secondmore » uses a particular factorization of the three body phase-space measure and the knowledge of the scaling properties of the integral itself. Our result is presented as a Laurent expansion in the dimensional regulator, although some of the master integrals are computed to all orders in this parameter.« less

  13. Soft Expansion of Double-Real-Virtual Corrections to Higgs Production at N$^3$LO

    SciTech Connect

    Anastasiou, Charalampos; Duhr, Claude; Dulat, Falko; Furlan, Elisabetta; Herzog, Franz; Mistlberger, Bernhard

    2015-05-15

    We present methods to compute higher orders in the threshold expansion for the one-loop production of a Higgs boson in association with two partons at hadron colliders. This process contributes to the N3LO Higgs production cross section beyond the soft-virtual approximation. We use reverse unitarity to expand the phase-space integrals in the small kinematic parameters and to reduce the coefficients of the expansion to a small set of master integrals. We describe two methods for the calculation of the master integrals. The first was introduced for the calculation of the soft triple-real radiation relevant to N3LO Higgs production. The second uses a particular factorization of the three body phase-space measure and the knowledge of the scaling properties of the integral itself. Our result is presented as a Laurent expansion in the dimensional regulator, although some of the master integrals are computed to all orders in this parameter.

  14. Karhunen-Loève basis of Kolmogorov phase screens covering a rectangular stripe

    NASA Astrophysics Data System (ADS)

    Mathar, Richard J.

    2010-01-01

    Karhunen-Loève functions are statistically independent base functions to be multiplied with randomized coefficients to generate instances of the underlying statistics with specific covariances. In the context of numerical simulation of atmospheric turbulence, they are tools to generate phase distributions in the input pupil of telescope optics. Within the Taylor frozen screen approximation, the favorable geometry of phase screens is a stripe as wide as the telescope diameter, but much longer. A phase screen movie is generated by dragging the stripe across the telescope pupil. The aim is to avoid the wasteful alternative of cutting through a virtual circular phase screen with a diameter equal to the stripe's length. We calculate Karhunen-Loève functions over rectangular stripes by solving the well-known integral equation for isotropic variance of the phase distribution. They are expanded in products of Legendre functions along the two Cartesian coordinates, represented by spherical Bessel functions in Fourier space. The rectangular shape of the integral's domain breaks the symmetry of the structure function. Yet, the matrix elements of the eigenvalue equation can be calculated by separating the primitive Cartesian basis via a Neumann series of radial and azimuthal terms.

  15. NASTRAN component-mode synthesis

    NASA Technical Reports Server (NTRS)

    Guyan, R. J.

    1976-01-01

    Procedure for dynamic substructuring analysis technique is generally as follows: calculation of component modes; selection of component normal modes, calculation of component generalized matrices, assembly of system matrices, and computation of normal modes; and retrieval of component response.

  16. Wall compliance and violin cavity modes.

    PubMed

    Bissinger, George

    2003-03-01

    Violin corpus wall compliance, which has a substantial effect on cavity mode frequencies, was added to Shaw's two-degree-of-freedom (2DOF) network model for A0 ("main air") and A1 (lowest length mode included in "main wood") cavity modes. The 2DOF model predicts a V(-0.25) volume dependence for A0 for rigid violin-shaped cavities, to which a semiempirical compliance correction term, V(-x(c)) (optimization parameter x(c)) consistent with cavity acoustical compliance and violin-based scaling was added. Optimizing x(c) over A0 and A1 frequencies measured for a Hutchins-Schelleng violin octet yielded x(c) approximately 0.08. This markedly improved A0 and A1 frequency predictions to within approximately +/- 10% of experiment over a range of about 4.5:1 in length, 10:1 in f-hole area, 3:1 in top plate thickness, and 128:1 in volume. Compliance is a plausible explanation for A1 falling close to the "main wood" resonance, not increasingly higher for the larger instruments, which were scaled successively shorter compared to the violin for ergonomic and practical reasons. Similarly incorporating compliance for A2 and A4 (lowest lower-/upper-bout modes, respectively) improves frequency predictions within +/-20% over the octet. PMID:12656403

  17. Cocaine withdrawal in rats selectively bred for low (LoS) versus high (HiS) saccharin intake.

    PubMed

    Radke, Anna K; Zlebnik, Natalie E; Carroll, Marilyn E

    2015-02-01

    Cocaine use results in anhedonia during withdrawal, but it is not clear how this emotional state interacts with an individual's vulnerability for addiction. Rats selectively bred for high (HiS) or low (LoS) saccharin intake are a well-established model of drug abuse vulnerability, with HiS rats being more likely to consume sweets and drugs of abuse such as cocaine and heroin (Carroll et al., 2002) than LoS rats. This study examined whether the motivational consequences of cocaine withdrawal are differentially expressed in HiS and LoS rats. HiS and LoS rats were trained to respond for a sucrose reward on a progressive ratio (PR) schedule of reinforcement and breakpoints were measured during and after chronic, continuous exposure to cocaine (30 mg/kg/day). Cocaine, but not saline, treatment resulted in lower breakpoints for sucrose during withdrawal in LoS rats only. These results suggest anhedonia during withdrawal is more pronounced in the less vulnerable LoS rats. Fewer motivational deficits during withdrawal may contribute to greater drug vulnerability in the HiS line. PMID:25482327

  18. Cocaine withdrawal in rats selectively bred for low (LoS) versus high (HiS) saccharin intake

    PubMed Central

    Radke, Anna K.; Zlebnik, Natalie E.; Carroll, Marilyn E.

    2014-01-01

    Cocaine use results in anhedonia during withdrawal, but it is not clear how this emotional state interacts with an individual's vulnerability for addiction. Rats selectively bred for high (HiS) or low (LoS) saccharin intake are a well-established model of drug abuse vulnerability, with HiS rats being more likely to consume sweets and drugs of abuse such as cocaine and heroin (Carroll et al. 2002) than LoS rats. This study examined whether the motivational consequences of cocaine withdrawal are differentially expressed in HiS and LoS rats. HiS and LoS rats were trained to respond for a sucrose reward on a progressive ratio (PR) schedule of reinforcement and breakpoints were measured during and after chronic, continuous exposure to cocaine (30 mg/kg/day). Cocaine, but not saline, treatment resulted in lower breakpoints for sucrose during withdrawal in LoS rats only. These results suggest anhedonia during withdrawal is more pronounced in the less vulnerable LoS rats. Fewer motivational deficits during withdrawal may contribute to drug vulnerability in the HiS line. PMID:25482327

  19. Whispering Bloch modes

    PubMed Central

    Craster, R. V.

    2016-01-01

    We investigate eigenvalue problems for the planar Helmholtz equation in open systems with a high order of rotational symmetry. The resulting solutions have similarities with the whispering gallery modes exploited in photonic micro-resonators and elsewhere, but unlike these do not necessarily require a surrounding material boundary, with confinement instead resulting from the geometry of a series of inclusions arranged in a ring. The corresponding fields exhibit angular quasi-periodicity reminiscent of Bloch waves, and hence we refer to them as whispering Bloch modes (WBMs). We show that if the geometry of the system is slightly perturbed such that the rotational symmetry is broken, modes with asymmetric field patterns can be observed, resulting in field enhancement and other potentially desirable effects. We investigate the WBMs of two specific geometries first using expansion methods and then by applying a two-scale asymptotic scheme. PMID:27493564

  20. The nonlinear tearing mode

    NASA Technical Reports Server (NTRS)

    Van Hoven, G.; Steinolfson, R. S.

    1984-01-01

    A series of nonlinear computations of tearing-mode development have been performed which achieve higher values of the magnetic Reynolds number and larger wavelengths than previously considered. A prime candidate for the realization of dynamic reconnection is the resistive magnetic tearing mode, a spontaneous instability of a stressed magnetic field. Typical simulations are described for a magnetic Lundquist number S of 10 to the 4th and wavelength parameters alpha from 0.05 to 0.5. In all cases, the nonlinear mode initially evolves at the linear growth rate, followed by a period of reduced growth. Another common feature is the formation of secondary flow vortices, near the tearing surface, which are opposite in direction to the initial linear vortices.

  1. Violin plate modes.

    PubMed

    Gough, Colin

    2015-01-01

    As the first step toward developing a generic model for the acoustically radiating vibrational modes of the violin and related instruments, the modes of both freely supported and edge-constrained top and back plates have been investigated as functions of shape, arching height, elastic anisotropy, the f-holes and associated island area, thickness graduations, and the additional boundary constraints of the ribs, soundpost, and bass-bar present in the assembled instrument. Comsol shell structure finite element software has been used as a quasi-experimental tool, with physical and geometric properties varied smoothly, often over several orders of magnitude, allowing the development of the plate modes to be followed continuously from those of an initially square plate to those of doubly-arched, guitar-shaped, orthotropic plates and their dependence on all the above factors. PMID:25618046

  2. ROTATIONAL SPLITTING OF PULSATION MODES

    SciTech Connect

    Deupree, Robert G.; Beslin, Wilfried

    2010-10-01

    Mode splittings produced by uniform rotation and a particular form of differential rotation are computed for two-dimensional rotating 10 M{sub sun} zero-age main sequence stellar models. The change in the character of the mode splitting is traced as a function of uniform rotation rate, and it is found that only relatively slow rotation rates are required before the mode splitting becomes asymmetric about the azimuthally symmetric (m = 0) mode. Increased rotation produces a progressively altered pattern of the individual modes with respect to each other. Large mode splittings begin to overlap with the mode splittings produced by different radial and latitudinal modes at relatively low rotation rates. The mode-splitting pattern for the differentially rotating stars we model is different than that for uniformly rotating stars, making the mode splitting a possible discriminant of the internal angular momentum distribution if one assumes that the formidable challenge of mode identification can be overcome.

  3. An I/Q mixer with an integrated differential quadrature all-pass filter for on-chip quadrature LO signal generation

    NASA Astrophysics Data System (ADS)

    Amin, Najam Muhammad; Zhigong, Wang; Zhiqun, Li

    2015-05-01

    A down-conversion in-phase/quadrature (I/Q) mixer employing a folded-type topology, integrated with a passive differential quadrature all-pass filter (D-QAF), in order to realize the final down-conversion stage of a 60 GHz receiver architecture is presented in this work. Instead of employing conventional quadrature generation techniques such as a polyphase filter or a frequency divider for the local oscillator (LO) of the mixer, a passive D-QAF structure is employed. Fabricated in a 65 nm CMOS process, the mixer exhibits a voltage gain of 7-8 dB in an intermediate frequency (IF) band ranging from 10 MHz-1.75 GHz. A fixed LO frequency of 12 GHz is used to down-convert a radio frequency (RF) band of 10.25-13.75 GHz. The mixer displays a third order input referred intercept point (IIP3) ranging from -8.75 to -7.37 dBm for a fixed IF frequency of 10 MHz and a minimum single-sideband noise figure (SSB-NF) of 11.3 dB. The mixer draws a current of 6 mA from a 1.2 V supply voltage dissipating a power of 7.2 mW. Project supported by the National High Technology Research and Development Program of China (No. 2011AA010200).

  4. A saw-less direct conversion long term evolution receiver with 25% duty-cycle LO in 130 nm CMOS technology

    NASA Astrophysics Data System (ADS)

    Siyuan, He; Changhong, Zhang; Liang, Tao; Weifeng, Zhang; Longyue, Zeng; Wei, Lü; Haijun, Wu

    2013-03-01

    A CMOS long-term evolution (LTE) direct convert receiver that eliminates the interstage SAW filter is presented. The receiver consists of a low noise variable gain transconductance amplifier (TCA), a quadrature passive current commutating mixer with a 25% duty-cycle LO, a trans-impedance amplifier (TIA), a 7th-order Chebyshev filter and programmable gain amplifiers (PGAs). A wide dynamic gain range is allocated in the RF and analog parts. A current commutating passive mixer with a 25% duty-cycle LO improves gain, noise, and linearity. An LPF based on a Tow-Thomas biquad suppresses out-of-band interference. Fabricated in a 0.13 μm CMOS process, the receiver chain achieves a 107 dB maximum voltage gain, 2.7 dB DSB NF (from PAD port), -11 dBm IIP3, and > +65 dBm IIP2 after calibration, 96 dB dynamic control range with 1 dB steps, less than 2% error vector magnitude (EVM) from 2.3 to 2.7 GHz. The total receiver (total I Q path) draws 89 mA from a 1.2-V LDO on chip supply.

  5. Multi-mode horn

    NASA Technical Reports Server (NTRS)

    Neilson, Jeffrey M. (Inventor)

    2002-01-01

    A horn has an input aperture and an output aperture, and comprises a conductive inner surface formed by rotating a curve about a central axis. The curve comprises a first arc having an input aperture end and a transition end, and a second arc having a transition end and an output aperture end. When rotated about the central axis, the first arc input aperture end forms an input aperture, and the second arc output aperture end forms an output aperture. The curve is then optimized to provide a mode conversion which maximizes the power transfer of input energy to the Gaussian mode at the output aperture.

  6. Screening materials with the XIA UltraLo alpha particle counter at Southern Methodist University

    NASA Astrophysics Data System (ADS)

    Nakib, M. Z.; Cooley, J.; Guiseppe, V. E.; Kara, B.; Qiu, H.; Rielage, K.; Schnee, R. W.; Scorza, S.

    2013-08-01

    Southern Methodist University houses one of five existing commercially available UltraLo 1800 production model alpha counters made by XIA LLC. The instrument has an electron drift chamber with a 707 cm2 or 1800 cm2 counting region which is determined by selecting the inner electrode size. The SMU team operating this device is part of the SuperCDMS screening working group, and uses the alpha counter to study the background rates from the decay of radon in materials used to construct the SuperCDMS experiment. We have studied four acrylic samples obtained from the MiniCLEAN direct dark matter search with the XIA instrument demonstrating its utility in low background experiments by investigating the plate-out of 210Pb and comparing the effectiveness of cleaning procedures in removing 222Rn progenies from the samples.

  7. Screening materials with the XIA UltraLo alpha particle counter at Southern Methodist University

    SciTech Connect

    Nakib, M. Z.; Cooley, J.; Kara, B.; Qiu, H.; Scorza, S.; Guiseppe, V. E.; Rielage, K.; Schnee, R. W.

    2013-08-08

    Southern Methodist University houses one of five existing commercially available UltraLo 1800 production model alpha counters made by XIA LLC. The instrument has an electron drift chamber with a 707 cm{sup 2} or 1800 cm{sup 2} counting region which is determined by selecting the inner electrode size. The SMU team operating this device is part of the SuperCDMS screening working group, and uses the alpha counter to study the background rates from the decay of radon in materials used to construct the SuperCDMS experiment. We have studied four acrylic samples obtained from the MiniCLEAN direct dark matter search with the XIA instrument demonstrating its utility in low background experiments by investigating the plate-out of {sup 210}Pb and comparing the effectiveness of cleaning procedures in removing {sup 222}Rn progenies from the samples.

  8. Starspot Modulation of BVRI Light Curves of LO Pegasi from 2012 June-October

    NASA Astrophysics Data System (ADS)

    Harmon, Robert O.; Avril, R.; Rossi De La Fuente, E.; Brechtel, C. E.

    2013-01-01

    We present BVRI light curves acquired at Perkins Observatory in 2012 June-October of the K8V star LO Pegasi, a young solar analog known to exhibit magnetic activity on its surface in the form of large starspots. We find that the amplitudes of the brightness variations have diminished significantly in comparison to data acquired from 2006-2011, and that the overall brightness is comparable to the brightness minima in the prior years. We speculate that these changes are due to the growth of a polar spot, coupled with a reduction in the relative sizes of projections of the polar spot into lower-latitude regions and/or a reduction in the area covered by independent spots at lower latitudes. This work was funded by the National Science Foundation Research Experiences for Undergraduates Program Award #1003992 and Ohio Wesleyan University.

  9. Stellar Surface Image of LO Pegasi via Light-curve Inversion

    NASA Astrophysics Data System (ADS)

    Harmon, Robert O.; Moore, C.; Decker, R.

    2009-01-01

    We present images of dark starspots on the surface of the K8 main-sequence star LO Pegasi. CCD images of the star and surrounding field were acquired through B, V, R and I filters at Perkins Observatory in June and July, 2008. The images were dark-subtracted and flat-fielded and then aperture photometry was performed to yield light curves through each of the four filters. These light curves were then simultaneously inverted via an algorithm devised by one of us (Harmon) so as to yield images of the spots based on the rotational modulation they produced in the light curves. The use of multiple filters significantly improves the latitude resolution of the reconstructions. Comparison of our results with results from 2006 and 2007 shows that the spot structure was more complex in 2008 than in the prior years. This research was funded by the NSF REU Program and the Ohio Wesleyan University Summer Science Research Program.

  10. Photometric Imaging of Starspots on LO Pegasi in May, June and July of 2009

    NASA Astrophysics Data System (ADS)

    Harmon, Robert O.; Miller, J.; Richard, A.

    2010-01-01

    CCD images of the K8 young solar analog LO Pegasi were obtained during May, June and July of 2009 through B, V, R, and I photometric filters at Perkins Observatory. Differential aperture photometry was performed on the images to generate light curves through each filter. The lightcurves were processed via the Light-Curve Inversion algorithm so as to invert the light curves to produce images of the star's photosphere. The locations of the starspots visible in the 2009 images are at lower latitudes than those deduced from the summer 2008 light curves. In addition, secular dimming since 2008 implies that there is a spot on the visible pole, which does not appear in our images because it does not significantly modulate the rotational light curve.

  11. Real-virtual contributions to the inclusive Higgs cross-section at N3LO

    NASA Astrophysics Data System (ADS)

    Anastasiou, Charalampos; Duhr, Claude; Dulat, Falko; Herzog, Franz; Mistlberger, Bernhard

    2013-12-01

    We compute the contributions to the N3LO inclusive Higgs boson cross-section from the square of one-loop amplitudes with a Higgs boson and three QCD partons as external states. Our result is a Taylor expansion in the dimensional regulator ɛ, where the coefficients of the expansion are analytic functions of the ratio of the Higgs boson mass and the partonic center of mass energy and they are valid for arbitrary values of this ratio. We also perform a threshold expansion around the limit of soft-parton radiation in the final state. The expressions for the coefficients of the threshold expansion are valid for arbitrary values of the dimension. As a by-product of the threshold expansion calculation, we have developed a soft expansion method at the integrand level by identifying the relevant soft and collinear regions for the loop-momentum.

  12. HIEN-LO: An experiment for charge determination of cosmic rays of interplanetary and solar origin

    NASA Technical Reports Server (NTRS)

    Klecker, B.; Hovestadt, D.; Mason, G. M.; Blake, J. B.; Nicholas, J.

    1988-01-01

    The experiment is designed to measure the heavy ion environment at low altitude (HIEN-LO) in the energy range 0.3 to 100 MeV/nucleon. In order to cover this wide energy range a complement of three sensors is used. A large area ion drift chamber and a time-of-flight telescope are used to determine the mass and energy of the incoming cosmic rays. A third omnidirectional counter serves as a proton monitor. The analysis of mass, energy and incoming direction in combination with the directional geomagnetic cut-off allows the determination of the ionic charge of the cosmic rays. The ionic charge in this energy range is of particular interest because it provides clues to the origin of these particles and to the plasma conditions at the acceleration site. The experiment is expected to be flown in 1988/1989.

  13. Vanishing absorption and blueshifted emission in FeLoBAL quasars

    NASA Astrophysics Data System (ADS)

    Rafiee, Alireza; Pirkola, Patrik; Hall, Patrick B.; Galati, Natalee; Rogerson, Jesse; Ameri, Abtin

    2016-07-01

    We study the dramatic decrease in iron absorption strength in the iron low-ionization broad absorption line quasar SDSS J084133.15+200525.8. We report on the continued weakening of absorption in the prototype of this class of variable broad absorption line quasar, FBQS J140806.2+305448. We also report a third example of this class, SDSS J123103.70+392903.6; unlike the other two examples, it has undergone an increase in observed continuum brightness (at 3000 Å rest frame) as well as a decrease in iron absorption strength. These changes could be caused by absorber transverse motion or by ionization variability. We note that the Mg II and UV Fe II lines in several FeLoBAL quasars are blueshifted by thousands of km s-1 relative to the H β emission line peak. We suggest that such emission arises in the outflowing winds normally seen only in absorption.

  14. Bayesian estimation of Karhunen-Loève expansions; A random subspace approach

    NASA Astrophysics Data System (ADS)

    Chowdhary, Kenny; Najm, Habib N.

    2016-08-01

    One of the most widely-used procedures for dimensionality reduction of high dimensional data is Principal Component Analysis (PCA). More broadly, low-dimensional stochastic representation of random fields with finite variance is provided via the well known Karhunen-Loève expansion (KLE). The KLE is analogous to a Fourier series expansion for a random process, where the goal is to find an orthogonal transformation for the data such that the projection of the data onto this orthogonal subspace is optimal in the L2 sense, i.e., which minimizes the mean square error. In practice, this orthogonal transformation is determined by performing an SVD (Singular Value Decomposition) on the sample covariance matrix or on the data matrix itself. Sampling error is typically ignored when quantifying the principal components, or, equivalently, basis functions of the KLE. Furthermore, it is exacerbated when the sample size is much smaller than the dimension of the random field. In this paper, we introduce a Bayesian KLE procedure, allowing one to obtain a probabilistic model on the principal components, which can account for inaccuracies due to limited sample size. The probabilistic model is built via Bayesian inference, from which the posterior becomes the matrix Bingham density over the space of orthonormal matrices. We use a modified Gibbs sampling procedure to sample on this space and then build probabilistic Karhunen-Loève expansions over random subspaces to obtain a set of low-dimensional surrogates of the stochastic process. We illustrate this probabilistic procedure with a finite dimensional stochastic process inspired by Brownian motion.

  15. Downregulation of MDM2 expression by RNAi inhibits LoVo human colorectal adenocarcinoma cells growth and the treatment of LoVo cells with mdm2siRNA3 enhances the sensitivity to cisplatin

    SciTech Connect

    Yu Yan . E-mail: gyfyuyan@hotmail.com; Sun Ping . E-mail: sunny19750502@hotmail.com; Sun Lichun; Liu Guoyi; Chen Guohua . E-mail: olivebranch_82@hotmail.com; Shang Lihua . E-mail: leval1000@sina.com; Wu Hongbo . E-mail: whpwl@sina.com; Hu Jing; Li Yue; Mao Yinling; Sui Guangjie; Sun Xiwen

    2006-01-06

    To investigate the biological effect of mdm2 in human colorectal adenocarcinoma LoVo cells, three mdm2siRNA constructions were recombinated and transient transfected into human colorectal adenocarcinoma LoVo cells with low differentiation character in vitro. The results showed that mdm2siRNA3 reduced mRNA level of mdm2 and protein level of mdm2, leading to proliferation inhibition on LoVo cells, and reduced tumor growth in nude mice. It was found that depletion of MDM2 in this pattern promoted apoptosis of LoVo cells and Cisplatin (DDP) treated in the mdm2siRNA3 transfected cell population would result in a substantial decrease by MTT colorimetry. Decreasing the MDM2 protein level in LoVo cells by RNAi could significantly inhibit tumor growth both in vitro and in vivo, which indicated that mdm2 gene played a definite role in the development and aggressiveness of human colon carcinoma. It also could be a therapeutic target in colorectal carcinoma. The synergistic activation of RNAi and cell toxicity agents indicated that the combination of chemotherapy and gene therapy will be a promising approach in the future.

  16. Sea-Level Flight Demonstration and Altitude Characterization of a LO2/LCH4 Based Accent Propulsion Lander

    NASA Technical Reports Server (NTRS)

    Collins, Jacob; Hurlbert, Eric; Romig, Kris; Melcher, John; Hobson, Aaron; Eaton, Phil

    2009-01-01

    A 1,500 lbf thrust-class liquid oxygen (LO2)/Liquid Methane (LCH4) rocket engine was developed and tested at both sea-level and simulated altitude conditions. The engine was fabricated by Armadillo Aerospace (AA) in collaboration with NASA Johnson Space Center. Sea level testing was conducted at Armadillo Aerospace facilities at Caddo Mills, TX. Sea-level tests were conducted using both a static horizontal test bed and a vertical take-off and landing (VTOL) test bed capable of lift-off and hover-flight in low atmosphere conditions. The vertical test bed configuration is capable of throttling the engine valves to enable liftoff and hover-flight. Simulated altitude vacuum testing was conducted at NASA Johnson Space Center White Sands Test Facility (WSTF), which is capable of providing altitude simulation greater than 120,000 ft equivalent. The engine tests demonstrated ignition using two different methods, a gas-torch and a pyrotechnic igniter. Both gas torch and pyrotechnic ignition were demonstrated at both sea-level and vacuum conditions. The rocket engine was designed to be configured with three different nozzle configurations, including a dual-bell nozzle geometry. Dual-bell nozzle tests were conducted at WSTF and engine performance data was achieved at both ambient pressure and simulated altitude conditions. Dual-bell nozzle performance data was achieved over a range of altitude conditions from 90,000 ft to 50,000 ft altitude. Thrust and propellant mass flow rates were measured in the tests for specific impulse (Isp) and C* calculations.

  17. The Middeck 0-gravity Dynamics Experiment (MODE)

    NASA Technical Reports Server (NTRS)

    Crawley, Edward F.; Deluis, Javier

    1992-01-01

    Viewgraphs on the middeck 0-gravity dynamics experiment (MODE) are presented. Topics covered include: MODE flight hardware elements; MODE science objectives; MODE team; flight operations; and summary.

  18. Thermodynamics of Radiation Modes

    ERIC Educational Resources Information Center

    Pina, Eduardo; de la Selva, Sara Maria Teresa

    2010-01-01

    We study the equilibrium thermodynamics of the electromagnetic radiation in a cavity of a given volume and temperature. We found three levels of description, the thermodynamics of one mode, the thermodynamics of the distribution of frequencies in a band by summing over the frequencies in it and the global thermodynamics by summing over all the…

  19. Two Modes of Sexuality.

    ERIC Educational Resources Information Center

    Firestone, Robert W.

    This paper describes the essential difference between two modes of sexual relating: (1) a personal, outward style of interaction that is the natural extension of affection, tenderness, and companionship between two people; and (2) an impersonal, inward, more masturbatory expression in which sex is used primarily as a narcotic. The origins of…

  20. Theories and Modes

    ERIC Educational Resources Information Center

    Apsche, Jack A.

    2005-01-01

    In his work on the Theory of Modes, Beck (1996) suggested that there were flaws with his cognitive theory. He suggested that though there are shortcomings to his cognitive theory, there were not similar shortcomings to the practice of Cognitive Therapy. The author suggests that if there are shortcomings to cognitive theory the same shortcomings…

  1. Synthesize Modes and Correlate

    2005-10-01

    SMAC is an automated experimental modal parameter extraction package which determines the natural frequencies of vibration, viscous damping ratios and mode shapes from experimental accelerance frequency response functions (FRFs). It is written in the MATLAB interpretive matrix language and has a graphical user interface.

  2. Mode conversion in ITER

    NASA Astrophysics Data System (ADS)

    Jaeger, E. F.; Berry, L. A.; Myra, J. R.

    2006-10-01

    Fast magnetosonic waves in the ion cyclotron range of frequencies (ICRF) can convert to much shorter wavelength modes such as ion Bernstein waves (IBW) and ion cyclotron waves (ICW) [1]. These modes are potentially useful for plasma control through the generation of localized currents and sheared flows. As part of the SciDAC Center for Simulation of Wave-Plasma Interactions project, the AORSA global-wave solver [2] has been ported to the new, dual-core Cray XT-3 (Jaguar) at ORNL where it demonstrates excellent scaling with the number of processors. Preliminary calculations using 4096 processors have allowed the first full-wave simulations of mode conversion in ITER. Mode conversion from the fast wave to the ICW is observed in mixtures of deuterium, tritium and helium3 at 53 MHz. The resulting flow velocity and electric field shear will be calculated. [1] F.W. Perkins, Nucl. Fusion 17, 1197 (1977). [2] E.F. Jaeger, L.A. Berry, J.R. Myra, et al., Phys. Rev. Lett. 90, 195001-1 (2003).

  3. Modes of Communication

    ERIC Educational Resources Information Center

    Dewatripont, Mathias; Tirole, Jean

    2005-01-01

    The paper develops a theory of costly communication in which the sender's and receiver's motivations and abilities endogenously determine the communication mode and the transfer of knowledge. Communication is modeled as a problem of moral hazard in teams, in which the sender and receiver select persuasion and message elaboration efforts. The model…

  4. Effect of a 5-lipoxygenase (5-LO)/cyclooxygenase (CO) inhibitor, WY-47, 288, on cutaneous models of inflammation.

    PubMed

    Carlson, R P; O'Neill-Davis, L; Calhoun, W; Datko, L; Musser, J H; Kreft, A F; Chang, J Y

    1989-03-01

    WY-47,288 (2-[(1-naphthalenyloxy)methyl]quinoline) demonstrated topical antiinflammatory activity in several animal models of skin inflammation. Application of WY-47,288 to mouse ear surfaces inhibited arachidonic acid (ED50 = 0.3 mg/ear) and tetradecanoylphorbol acetate (TPA)-induced inflammation (40% at 1 mg/ear). Administration of WY-47,288 (1 mg/ear) at 30 min and 5 h after TPA reduced ear edema and epidermal proliferation by 50%. WY-47,288 also inhibited oxazolone-induced contact hypersensitivity in mouse ears (ED50 = 0.4 mg/ear) and UVB-induced guinea pig skin erythema (ED50 approximately 0.25 mg/spot). These antiinflammatory effects may be due to inhibition of 5-lipoxygenase (5-LO) and cyclooxygenase (CO) since the synthesis of 5-LO and CO products by rat neutrophils and mouse macrophages was dose-dependently reduced by WY-47,288. By contrast, WY-47,288 demonstrated no appreciable inhibition of 12-LO (rabbit platelet), 15-LO (soybean) or phospholipase A2 (human platelet). Furthermore, no systemic adverse effects were observed after topical, parenteral or oral administration of WY-47,288, suggesting that WY-47,288 is a safe topical 5-LO/CO inhibitor for treating skin inflammation. PMID:2500009

  5. Selenoprotein Genes Exhibit Differential Expression Patterns Between Hepatoma HepG2 and Normal Hepatocytes LO2 Cell Lines.

    PubMed

    Zhao, Hua; Tang, Jiayong; Xu, Jingyang; Cao, Lei; Jia, Gang; Long, Dingbiao; Liu, Guangmang; Chen, Xiaoling; Wang, Kangning

    2015-10-01

    The purpose of this study was to compare messenger RNA (mRNA) expression of selenoprotein genes between hepatoma HepG2 and normal hepatocytes LO2 cell lines. Liver HepG2 and LO2 cells were cultured in 12-well plates under the same condition until cells grew to complete confluence, and then cells were harvested for total RNA and protein extraction. The qPCRs were performed to compare gene expression of 14 selenoprotein genes and 5 cancer signaling-related genes. Enzyme activities were also assayed. The results showed that human hepatoma HepG2 cells grew faster than normal hepatocytes LO2 cells. Among the genes investigated, 10 selenoprotein genes (Gpx1, Gpx3, Gpx4, Selx, Sepp, Sepw1, Sepn1, Selt, Seli, Selh) and 3 cancer signaling-related genes (Bcl-2A, caspase-3, and P38) were upregulated (P < 0.05), while Selo and Bcl-2B were downregulated (P < 0.05) in hepatoma HepG2 cells compared to LO2 cells. Significant correlations were found between selenoprotein genes and the cancer signaling-related genes Caspase3, P53, Bc1-2A, and Bc1-2B. Our results revealed that selenoprotein genes were aberrantly expressed in hepatoma HepG2 cells compared to normal liver LO2 cells, which indicated that those selenoprotein genes may play important roles in the occurrence and development of liver carcinogenesis. PMID:25846212

  6. LoFEx — A local framework for calculating excitation energies: Illustrations using RI-CC2 linear response theory

    NASA Astrophysics Data System (ADS)

    Baudin, Pablo; Kristensen, Kasper

    2016-06-01

    We present a local framework for the calculation of coupled cluster excitation energies of large molecules (LoFEx). The method utilizes time-dependent Hartree-Fock information about the transitions of interest through the concept of natural transition orbitals (NTOs). The NTOs are used in combination with localized occupied and virtual Hartree-Fock orbitals to generate a reduced excitation orbital space (XOS) specific to each transition where a standard coupled cluster calculation is carried out. Each XOS is optimized to ensure that the excitation energies are determined to a predefined precision. We apply LoFEx in combination with the RI-CC2 model to calculate the lowest excitation energies of a set of medium-sized organic molecules. The results demonstrate the black-box nature of the LoFEx approach and show that significant computational savings can be gained without affecting the accuracy of CC2 excitation energies.

  7. Modes of Learning.

    ERIC Educational Resources Information Center

    Partridge, Susan

    This literature review is divided into two parts. The first part is a survey of materials in the William S. Gray Collection at the University of Chicago that deal with modes of learning. The studies reviewed range from the 1930s to the 1960s. The second part of the paper extends the review to studies published during the 1970s. Each section of the…

  8. Single mode cavity laser

    SciTech Connect

    Martin, D.W.; Levy, J.L.

    1984-01-17

    This external cavity laser utilizes an unstable resonator in conjuction with a high reflectivity stripe end mirror which is oriented substantially parallel to the plane of the maximum divergence of the laser diode output beam and whose axis is substantially parallel to the plane of the junction of the laser diode. This configuration operates with high efficiency to select only the fundamental mode of the laser diode with a minimal divergence in the output beam.

  9. Summary of LO2/Ethanol OMS/RCS Technology and Advanced Development 99-2744

    NASA Technical Reports Server (NTRS)

    Curtis, Leslie A.; Hurlbert, Eric A.

    1999-01-01

    NASA is pursuing non-toxic propellant technologies applicable to RLV and Space Shuttle orbital maneuvering system (OMS) and reaction control system (RCS). The primary objectives of making advancements in an OMS/RCS system are improved safety, reliability, and reduced operations and maintenance cost, while meeting basic operational and performance requirements. An OMS/RCS has a high degree of direct interaction with the vehicle and crew and requires subsystem and components that are compatible with integration into the vehicle with regard to external mold-line, power, and thermal control. In July 1997, a Phase I effort for the technology and advanced development of an upgrade of the space shuttle was conducted to define the system architecture, propellant tank, feed system, RCS thrusters, and OMS engine. Phase I of the project ran from July 1997 to October 1998. Phase II is currently being planned for the development and test of full-scale prototype of the system in 1999 and 2000. The choice of pressure-fed liquid oxygen (LO2) and ethanol is the result of numerous trade studies conducted from 1980 to 1996. Liquid oxygen and ethanol are clean burning, high-density propellants that provide a high degree of commonality with other spacecraft subsystems including life support, power, and thermal control, and with future human exploration and development of space missions. The key to this pressure-fed system is the use of subcooled liquid oxygen at 350 psia. In this approach, there is 80 degrees R of subcooling, which means that boil-off will not occur until the temperature has risen 80 R. The sub-cooling results naturally from loading propellants at 163 R, which is the saturation temperature at 14.7 psia, and then pressurizing to 350 psia on the launch pad. Thermal insulation and conditioning techniques are then used to limit the LO2 temperature to 185 R maximum, and maintain the sub-cooling. The other key is the wide temperature range of ethanol, -173 F to +300 F, which

  10. Encoding/decoding using superpositions of spatial modes for image transfer in km-scale few-mode fiber.

    PubMed

    Zhu, Long; Liu, Jun; Mo, Qi; Du, Cheng; Wang, Jian

    2016-07-25

    Space domain is regarded as the only known physical dimension left of lightwave to exploit in optical communications. Recently, lots of research efforts have been devoted to using spatial modes of fibers to increase data transmission capacity in optical fiber communications. In this paper, we propose and demonstrate a different approach to exploiting the space dimension, i.e. transferring image by space dimension encoding/decoding using superpositions of spatial modes in km-scale few-mode fiber. Three grayscale images are successfully transmitted through a 1.1-km few-mode fiber by employing either 4 modes, i.e. three linearly polarized (LP) modes of LP01, LP11a, LP11b and one orbital angular momentum (OAM) mode of OAM-1, or 2 modes (OAM+1, OAM-1). The bit-error rate is evaluated and zero error among all received data is achieved, showing favorable fiber link communication performance using the spatial modes of fiber for encoding/decoding. Moreover, we also demonstrate the 4 modes (LP01, LP11a, LP11b and OAM-1) encoding/decoding for image transfer in a 10-km few-mode fiber in the experiment. PMID:27464145

  11. Probing plasmonic breathing modes optically

    SciTech Connect

    Krug, Markus K. Reisecker, Michael; Hohenau, Andreas; Ditlbacher, Harald; Trügler, Andreas; Hohenester, Ulrich; Krenn, Joachim R.

    2014-10-27

    The confinement of surface plasmon modes in flat nanoparticles gives rise to plasmonic breathing modes. With a vanishing net dipole moment, breathing modes do not radiate, i.e., they are optically dark. Having thus escaped optical detection, breathing modes were only recently revealed in silver nanodisks with electron energy loss spectroscopy in an electron microscope. We show that for disk diameters >200 nm, retardation induced by oblique optical illumination relaxes the optically dark character. This makes breathing modes and thus the full plasmonic mode spectrum accessible to optical spectroscopy. The experimental spectroscopy data are in excellent agreement with numerical simulations.

  12. Karhunen-Loève expansion revisited for vector-valued random fields: Scaling, errors and optimal basis.

    NASA Astrophysics Data System (ADS)

    Perrin, G.; Soize, C.; Duhamel, D.; Funfschilling, C.

    2013-06-01

    Due to scaling effects, when dealing with vector-valued random fields, the classical Karhunen-Loève expansion, which is optimal with respect to the total mean square error, tends to favorize the components of the random field that have the highest signal energy. When these random fields are to be used in mechanical systems, this phenomenon can introduce undesired biases for the results. This paper presents therefore an adaptation of the Karhunen-Loève expansion that allows us to control these biases and to minimize them. This original decomposition is first analyzed from a theoretical point of view, and is then illustrated on a numerical example.

  13. Constraining primordial vector mode from B-mode polarization

    SciTech Connect

    Saga, Shohei; Ichiki, Kiyotomo; Shiraishi, Maresuke E-mail: maresuke.shiraishi@pd.infn.it

    2014-10-01

    The B-mode polarization spectrum of the Cosmic Microwave Background (CMB) may be the smoking gun of not only the primordial tensor mode but also of the primordial vector mode. If there exist nonzero vector-mode metric perturbations in the early Universe, they are known to be supported by anisotropic stress fluctuations of free-streaming particles such as neutrinos, and to create characteristic signatures on both the CMB temperature, E-mode, and B-mode polarization anisotropies. We place constraints on the properties of the primordial vector mode characterized by the vector-to-scalar ratio r{sub v} and the spectral index n{sub v} of the vector-shear power spectrum, from the Planck and BICEP2 B-mode data. We find that, for scale-invariant initial spectra, the ΛCDM model including the vector mode fits the data better than the model including the tensor mode. The difference in χ{sup 2} between the vector and tensor models is Δχ{sup 2} = 3.294, because, on large scales the vector mode generates smaller temperature fluctuations than the tensor mode, which is preferred for the data. In contrast, the tensor mode can fit the data set equally well if we allow a significantly blue-tilted spectrum. We find that the best-fitting tensor mode has a large blue tilt and leads to an indistinct reionization bump on larger angular scales. The slightly red-tilted vector mode supported by the current data set can also create O(10{sup -22})-Gauss magnetic fields at cosmological recombination. Our constraints should motivate research that considers models of the early Universe that involve the vector mode.

  14. Three Modes of Air Atmospheric Pressure Plasma

    NASA Astrophysics Data System (ADS)

    Mohamed, Abdel-Aleam H.

    2015-09-01

    Atmospheric pressure plasma jet operating in air have gained a high interest due to its various applications in industry and biomedical. The presented air plasma jet system is consisted of stainless steel hollow needle electrode of 1 mm inner diameter which is covered with a quartz tube with a 1 mm diameter side hole. The hole is above the tube nozzle by 5 mm and it is covered by a copper ring which is connected to the ground. The needle is connected to sinusoidal 27 kHz high voltage power supply (25 kV) though a current limiting resistor of 50 k Ω. The tested distance between the needle tip and the side hole was 1 mm or 2.1 mm gape. The electric and plasma jet formation characteristics show three modes of operations. Through these modes the plasma length changes with air flow rate to increase in the first mode and to confine inside the quartz tube in the second mode, then it start to eject from the nozzle again and increase with flow rate to reach a maximum length of 7 mm at 4.5 SLM air flow rate in the third mode. The measured gas temperature of the plasma jet can approach room temperature (300 K). Moreover, the plasma jet emission spectra shows the presence of reactive O and OH radical in the plasma jet. These results indicate that the generated air plasma jet can be used a plasma sterilization.

  15. Optimized suppression of coherent noise from seismic data using the Karhunen-Loève transform.

    PubMed

    Montagne, Raúl; Vasconcelos, Giovani L

    2006-07-01

    Signals obtained in land seismic surveys are usually contaminated with coherent noise, among which the ground roll (Rayleigh surface waves) is of major concern for it can severely degrade the quality of the information obtained from the seismic record. This paper presents an optimized filter based on the Karhunen-Loève transform for processing seismic images contaminated with ground roll. In this method, the contaminated region of the seismic record, to be processed by the filter, is selected in such way as to correspond to the maximum of a properly defined coherence index. The main advantages of the method are that the ground roll is suppressed with negligible distortion of the remnant reflection signals and that the filtering procedure can be automated. The image processing technique described in this study should also be relevant for other applications where coherent structures embedded in a complex spatiotemporal pattern need to be identified in a more refined way. In particular, it is argued that the method is appropriate for processing optical coherence tomography images whose quality is often degraded by coherent noise (speckle). PMID:16907183

  16. On the application of Karhunen-Loève transform to transient dynamic systems

    NASA Astrophysics Data System (ADS)

    Glüsmann, Philipp; Kreuzer, Edwin

    2009-12-01

    The Karhunen-Loève transform (KLT) has become a popular method in various fields of engineering science. Due to its ability to identify the most prominent features in the underlying system dynamics the KLT is a favorable method for such tasks as process monitoring, model order reduction or optimum control. However, it is a well-known fact that the KLT is 'case sensitive'. That is that changes in the dynamic system behavior can decisively affect the KLT results. As much as this property is desired for monitoring problems, it limits the performance of KLT in model order reduction or optimum control problems, if systems are subject to structural changes. Recent research interest focuses on extending applications of KLT to systems with transient dynamic behavior or changing boundary conditions. Approaches have been published that circumvent the limitations of KLT by either assuming reasonable comparability of system dynamics or by measuring the representative performance of KLT-bases a posteriori. However, such methods require additional simulations of the full size system and thus jeopardize the idea of model order reduction. In this paper, we introduce a novel a priori measure to evaluate the performance of the current KLT-basis. This procedure can be of great help in either monitoring or adaptive control of systems that show intermittent transient and (quasi-)stationary dynamic behavior. This a priori measure prepares the path for adaptive model order reduction schemes. Moreover, it can be used to measure the stationarity of multidimensional dynamic processes.

  17. Aggregation of LoD 1 building models as an optimization problem

    NASA Astrophysics Data System (ADS)

    Guercke, R.; Götzelmann, T.; Brenner, C.; Sester, M.

    3D city models offered by digital map providers typically consist of several thousands or even millions of individual buildings. Those buildings are usually generated in an automated fashion from high resolution cadastral and remote sensing data and can be very detailed. However, not in every application such a high degree of detail is desirable. One way to remove complexity is to aggregate individual buildings, simplify the ground plan and assign an appropriate average building height. This task is computationally complex because it includes the combinatorial optimization problem of determining which subset of the original set of buildings should best be aggregated to meet the demands of an application. In this article, we introduce approaches to express different aspects of the aggregation of LoD 1 building models in the form of Mixed Integer Programming (MIP) problems. The advantage of this approach is that for linear (and some quadratic) MIP problems, sophisticated software exists to find exact solutions (global optima) with reasonable effort. We also propose two different heuristic approaches based on the region growing strategy and evaluate their potential for optimization by comparing their performance to a MIP-based approach.

  18. Study of LO-phonon decay in semiconductors for hot carrier solar cell

    NASA Astrophysics Data System (ADS)

    Levard, Hugo; Vidal, Julien; Laribi, Sana; Guillemoles, Jean-François

    2014-03-01

    Knowledge of phonon decay is of crucial importance when studying basic properties of semiconductors, since they are closely related to Raman linewidth and non-equilibrium-hot-carriers cooling. The latter indeed cools down to the bottom of the conduction band within a picosecond range because of electron-phonon interaction. The eventual emitted hot phonons then decay in few picoseconds. The hot carriers cooling can be slowed down by considering the decay rate dependence of phonon on conservation rules, whose tuning may reduce the allowed two-phonon final states density. This is of direct interest for the third generation photovoltaic devices that are Hot Carrier Solar Cells (HCSC), in which the photoexcited carriers are extracted at an energy higher than thermal equilibrium. One of the HCSC main challenges then is to find an absorber material in which the hot phonons has a relaxation time longer than the carriers cooling time, so that we can expect the electron to ``reabsorb'' a phonon, slowing down the electronic cooling. HCSC yield is ultimately limited by LO phonon decay, though. In this work, we present theoretical results obtained from ab initio calculations of phonon lifetime in III-V and IV-IV semiconductors through a three-phonon process. Common approximations in the literature are questioned. In particular, we show that the usual ``zone-center approximation'' is not valid in some specific semiconductors. The analysis allows to correctly investigate phonon decay mechanisms in bulk and nanostructured materials.

  19. Architecture for a 1-GHz Digital RADAR

    NASA Technical Reports Server (NTRS)

    Mallik, Udayan

    2011-01-01

    An architecture for a Direct RF-digitization Type Digital Mode RADAR was developed at GSFC in 2008. Two variations of a basic architecture were developed for use on RADAR imaging missions using aircraft and spacecraft. Both systems can operate with a pulse repetition rate up to 10 MHz with 8 received RF samples per pulse repetition interval, or at up to 19 kHz with 4K received RF samples per pulse repetition interval. The first design describes a computer architecture for a Continuous Mode RADAR transceiver with a real-time signal processing and display architecture. The architecture can operate at a high pulse repetition rate without interruption for an infinite amount of time. The second design describes a smaller and less costly burst mode RADAR that can transceive high pulse repetition rate RF signals without interruption for up to 37 seconds. The burst-mode RADAR was designed to operate on an off-line signal processing paradigm. The temporal distribution of RF samples acquired and reported to the RADAR processor remains uniform and free of distortion in both proposed architectures. The majority of the RADAR's electronics is implemented in digital CMOS (complementary metal oxide semiconductor), and analog circuits are restricted to signal amplification operations and analog to digital conversion. An implementation of the proposed systems will create a 1-GHz, Direct RF-digitization Type, L-Band Digital RADAR--the highest band achievable for Nyquist Rate, Direct RF-digitization Systems that do not implement an electronic IF downsample stage (after the receiver signal amplification stage), using commercially available off-the-shelf integrated circuits.

  20. Calculation of infrared and Raman vibration modes of magnesite at high pressure by density-functional perturbation theory and comparison with experiments

    NASA Astrophysics Data System (ADS)

    Clark, Stewart J.; Jouanna, Paul; Haines, Julien; Mainprice, David

    2011-03-01

    We predict the IR-TO, IR-LO and Raman modes (wave numbers and intensities) of magnesite (MgCO3) up to 50 GPa, at T = 0 K, using the density-functional perturbation theory up to a third order perturbation, under the harmonic assumption. The predicted IR-TO and Raman mode wave numbers, the mode Grüneisen parameters and the Davydov splittings are systematically compared with experimental data for all modes up to the pressures of 10-30 GPa and for some modes up to 50 GPa. Existing experiments allow extending this comparison only to IR-LO wave numbers of the E u (ν3) asymmetric-stretch mode, confirming the odd experimental behavior of this mode at very high pressures. Predicted IR-TO, IR-LO and Raman intensities up to 50 GPa are just tabulated, but data are missing for their comparison with precise experiments. However, the generally good agreement observed between numerical results and experimental data, when their comparison is possible, suggests that first-principles methods are a major help to predict the entire spectrum up to very high pressures.

  1. Temperature-dependent exciton resonance energies and their correlation with IR-active optical phonon modes in β-Ga2O3 single crystals

    NASA Astrophysics Data System (ADS)

    Onuma, T.; Saito, S.; Sasaki, K.; Goto, K.; Masui, T.; Yamaguchi, T.; Honda, T.; Kuramata, A.; Higashiwaki, M.

    2016-03-01

    Temperature-dependent exciton resonance energies Eexciton in β-Ga2O3 single crystals are studied by using polarized reflectance measurement. The Eexciton values exhibit large energy changes in the range of 179-268 meV from 5 to 300 K. The IR-active Au and Bu optical phonon modes are selectively observed in the IR spectroscopic ellipsometry spectra by reflecting the polarization selection rules. The longitudinal optical (LO) phonon energies can be divided into three ranges: ℏωLO = 35-48, 70-73, and 88-99 meV. The broadening parameters, which are obtained from the reflectance measurements, correspond to the lower two ranges of ℏωLO at low temperature and 75 meV above 150 K. The large Eexciton changes with temperature in β-Ga2O3 are found to be originated from the exciton-LO-phonon interaction.

  2. Technology requirements for advanced earth orbital transportation systems. Volume 3: Summary report - dual mode propulsion

    NASA Technical Reports Server (NTRS)

    Hepler, A. K.; Bangsund, E. L.

    1978-01-01

    The impact of dual-mode propulsion on cost-effective technology requirements for advanced earth-orbital transportation systems is considered. Additional objectives were to determine the advantages of the best dual mode concept relative to the LO2/LH2 concept of the basic study. Normal technology requirements applicable to horizontal take-off and landing single-stage-to-orbit systems utilizing dual mode rocket propulsion were projected to the 1985 time period. These technology projections were then incorporated in a vehicle parametric design analysis for two different operational concepts of a dual mode propulsion system. The resultant performance, weights and costs of each concept were compared. The selected propulsion concept was evaluated to confirm the parametric trending/scaling of weights and to optimize the configuration.

  3. Free boundary ballooning mode representation

    SciTech Connect

    Zheng, L. J.

    2012-10-15

    A new type of ballooning mode invariance is found in this paper. Application of this invariance is shown to be able to reduce the two-dimensional problem of free boundary high n modes, such as the peeling-ballooning modes, to a one-dimensional problem. Here, n is toroidal mode number. In contrast to the conventional ballooning representation, which requires the translational invariance of the Fourier components of the perturbations, the new invariance reflects that the independent solutions of the high n mode equations are translationally invariant from one radial interval surrounding a single singular surface to the other intervals. The conventional ballooning mode invariance breaks down at the vicinity of plasma edge, since the Fourier components with rational surfaces in vacuum region are completely different from those with rational surfaces in plasma region. But, the new type of invariance remains valid. This overcomes the limitation of the conventional ballooning mode representation for studying free boundary modes.

  4. MODE: Structural Test Article (STA)

    NASA Technical Reports Server (NTRS)

    Crawley, Edward F.; Masters, Brett

    1992-01-01

    Viewgraphs on the Middeck 0-gravity Dynamics Experiment (MODE): Structural Test Article (STA) are presented. Topics covered include: MODE: structural test article motivation; hardware; sensors and actuators; experimental support module; data; preliminary results; supporting analysis program; and modeling approach.

  5. Maximum thrust mode evaluation

    NASA Technical Reports Server (NTRS)

    Orme, John S.; Nobbs, Steven G.

    1995-01-01

    Measured reductions in acceleration times which resulted from the application of the F-15 performance seeking control (PSC) maximum thrust mode during the dual-engine test phase is presented as a function of power setting and flight condition. Data were collected at altitudes of 30,000 and 45,000 feet at military and maximum afterburning power settings. The time savings for the supersonic acceleration is less than at subsonic Mach numbers because of the increased modeling and control complexity. In addition, the propulsion system was designed to be optimized at the mid supersonic Mach number range. Recall that even though the engine is at maximum afterburner, PSC does not trim the afterburner for the maximum thrust mode. Subsonically at military power, time to accelerate from Mach 0.6 to 0.95 was cut by between 6 and 8 percent with a single engine application of PSC, and over 14 percent when both engines were optimized. At maximum afterburner, the level of thrust increases were similar in magnitude to the military power results, but because of higher thrust levels at maximum afterburner and higher aircraft drag at supersonic Mach numbers the percentage thrust increase and time to accelerate was less than for the supersonic accelerations. Savings in time to accelerate supersonically at maximum afterburner ranged from 4 to 7 percent. In general, the maximum thrust mode has performed well, demonstrating significant thrust increases at military and maximum afterburner power. Increases of up to 15 percent at typical combat-type flight conditions were identified. Thrust increases of this magnitude could be useful in a combat situation.

  6. Localized acoustic surface modes

    NASA Astrophysics Data System (ADS)

    Farhat, Mohamed; Chen, Pai-Yen; Bağcı, Hakan

    2016-04-01

    We introduce the concept of localized acoustic surface modes. We demonstrate that they are induced on a two-dimensional cylindrical rigid surface with subwavelength corrugations under excitation by an incident acoustic plane wave. Our results show that the corrugated rigid surface is acoustically equivalent to a cylindrical scatterer with uniform mass density that can be represented using a Drude-like model. This, indeed, suggests that plasmonic-like acoustic materials can be engineered with potential applications in various areas including sensing, imaging, and cloaking.

  7. Damage mechanics - failure modes

    SciTech Connect

    Krajcinovic, D.; Vujosevic, M.

    1996-12-31

    The present study summarizes the results of the DOE sponsored research program focused on the brittle failure of solids with disordered microstructure. The failure is related to the stochastic processes on the microstructural scale; namely, the nucleation and growth of microcracks. The intrinsic failure modes, such as the percolation, localization and creep rupture, are studied by emphasizing the effect of the micro-structural disorder. A rich spectrum of physical phenomena and new concepts that emerges from this research demonstrates the reasons behind the limitations of traditional, deterministic, and local continuum models.

  8. Raman scattering by the E{sub 2h} and A{sub 1}(LO) phonons of In{sub x}Ga{sub 1-x}N epilayers (0.25 < x < 0.75) grown by molecular beam epitaxy

    SciTech Connect

    Oliva, R.; Ibanez, J.; Cusco, R.; Artus, L.; Kudrawiec, R.; Serafinczuk, J.; Henini, M.; Boney, C.; Bensaoula, A.

    2012-03-15

    We use Raman scattering to investigate the composition behavior of the E{sub 2h} and A{sub 1}(LO) phonons of In{sub x}Ga{sub 1-x}N and to evaluate the role of lateral compositional fluctuations and in-depth strain/composition gradients on the frequency of the A{sub 1}(LO) bands. For this purpose, we have performed visible and ultraviolet Raman measurements on a set of high-quality epilayers grown by molecular beam epitaxy with In contents over a wide composition range (0.25 < x < 0.75). While the as-measured A{sub 1}(LO) frequency values strongly deviate from the linear dispersion predicted by the modified random-element isodisplacement (MREI) model, we show that the strain-corrected A{sub 1}(LO) frequencies are qualitatively in good agreement with the expected linear dependence. In contrast, we find that the strain-corrected E{sub 2h} frequencies exhibit a bowing in relation to the linear behavior predicted by the MREI model. Such bowing should be taken into account to evaluate the composition or the strain state of InGaN material from the E{sub 2h} peak frequencies. We show that in-depth strain/composition gradients and selective resonance excitation effects have a strong impact on the frequency of the A{sub 1}(LO) mode, making very difficult the use of this mode to evaluate the strain state or the composition of InGaN material.

  9. ACCA College English Teaching Mode

    ERIC Educational Resources Information Center

    Ding, Renlun

    2008-01-01

    This paper elucidates a new college English teaching mode--"ACCA" (Autonomous Cooperative Class-teaching All-round College English Teaching Mode). Integrated theories such as autonomous learning and cooperative learning into one teaching mode, "ACCA", which is being developed and advanced in practice as well, is the achievement…

  10. Standardization of Keyword Search Mode

    ERIC Educational Resources Information Center

    Su, Di

    2010-01-01

    In spite of its popularity, keyword search mode has not been standardized. Though information professionals are quick to adapt to various presentations of keyword search mode, novice end-users may find keyword search confusing. This article compares keyword search mode in some major reference databases and calls for standardization. (Contains 3…

  11. CXCR6 marks a novel subset of T-bet(lo)Eomes(hi) natural killer cells residing in human liver.

    PubMed

    Stegmann, Kerstin A; Robertson, Francis; Hansi, Navjyot; Gill, Upkar; Pallant, Celeste; Christophides, Theodoros; Pallett, Laura J; Peppa, Dimitra; Dunn, Claire; Fusai, Giuseppe; Male, Victoria; Davidson, Brian R; Kennedy, Patrick; Maini, Mala K

    2016-01-01

    Natural killer cells (NK) are highly enriched in the human liver, where they can regulate immunity and immunopathology. We probed them for a liver-resident subset, distinct from conventional bone-marrow-derived NK. CXCR6+ NK were strikingly enriched in healthy and diseased liver compared to blood (p < 0.0001). Human hepatic CXCR6+ NK had an immature phenotype (predominantly CD56(bright)CD16-CD57-), and expressed the tissue-residency marker CD69. CXCR6+ NK produced fewer cytotoxic mediators and pro-inflammatory cytokines than the non-liver-specific CXCR6- fraction. Instead CXCR6+ NK could upregulate TRAIL, a key death ligand in hepatitis pathogenesis. CXCR6 demarcated liver NK into two transcriptionally distinct populations: T-bet(hi)Eomes(lo)(CXCR6-) and T-bet(lo)Eomes(hi)(CXCR6+); the latter was virtually absent in the periphery. The small circulating CXCR6+ subset was predominantly T-bet(hi)Eomes(lo), suggesting its lineage was closer to CXCR6- peripheral than CXCR6+ liver NK. These data reveal a large subset of human liver-resident T-bet(lo)Eomes(hi) NK, distinguished by their surface expression of CXCR6, adapted for hepatic tolerance and inducible anti-viral immunity. PMID:27210614

  12. Breeding for reduced post-harvest seed dormancy in switchgrass: registration of TEM-LoDorm switchgrass germplasm

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The switchgrass (Panicum virgatum L.) germplasm line TEM-LoDorm (Reg. No. GP-98, PI 636468) was developed by the USDA-ARS in cooperation with the Texas Agricultural Experiment Station (currently Texas AgriLife Research) and was released in May 2007. Establishment of desirable stands of switchgrass ...

  13. The LO Model and the Traditional French Organisational Culture: A Paradigmatic Contradiction Leading to a Limited Implementation

    ERIC Educational Resources Information Center

    Belet, Daniel

    2010-01-01

    This article deals with the issue of the very weak implementation of the LO model in France, although it appears as an appealing new management paradigm that can allow companies to better face a fast changing environment. The author argues that there is a strong philosophical contradiction between this innovative management model and the still…

  14. High-contrast 3D image acquisition using HiLo microscopy with an electrically tunable lens

    NASA Astrophysics Data System (ADS)

    Philipp, Katrin; Smolarski, André; Fischer, Andreas; Koukourakis, Nektarios; Stürmer, Moritz; Wallrabe, Ulricke; Czarske, Jürgen

    2016-04-01

    We present a HiLo microscope with an electrically tunable lens for high-contrast three-dimensional image acquisition. HiLo microscopy combines wide field and speckled illumination images to create optically sectioned images. Additionally, the depth-of-field is not fixed, but can be adjusted between wide field and confocal-like axial resolution. We incorporate an electrically tunable lens in the HiLo microscope for axial scanning, to obtain three-dimensional data without the need of moving neither the sample nor the objective. The used adaptive lens consists of a transparent polydimethylsiloxane (PDMS) membrane into which an annular piezo bending actuator is embedded. A transparent fluid is filled between the membrane and the glass substrate. When actuated, the piezo generates a pressure in the lens which deflects the membrane and thus changes the refractive power. This technique enables a large tuning range of the refractive power between 1/f = (-24 . . . 25) 1/m. As the NA of the adaptive lens is only about 0.05, a fixed high-NA lens is included in the setup to provide high resolution. In this contribution, the scan properties and capabilities of the tunable lens in the HiLo microscope are analyzed. Eventually, exemplary measurements are presented and discussed.

  15. Single-Mode VISAR

    SciTech Connect

    Krauter, K

    2007-11-16

    High energy-density physics (HEDP) experiments examine the properties of materials under extreme conditions. These experiments rely on the measurement of one or two velocities. These velocities are used to obtain Hugoniot relationships and thermodynamic equations of state. This methodology is referred to as 'velocimetry' and an instrument used to measure the shock wave is called a 'velocimeter' or a '(velocity) diagnostic'. The two most-widely used existing velocity diagnostics are; photonic Doppler velocimetry (PDV) and velocity interferometer system for any reflector (VISAR). PDV's advantages are a fast rise-time and ease of implementation but PDV has an upper velocity limit. Traditional implementations of VISAR have a rise time 10 times slower than PDV and are not easily implemented but are capable of measuring any velocity produced during HEDP experiments. This thesis describes a novel method of combining the positive attributes of PDV and VISAR into a more cost effective diagnostic called a Single-Mode VISAR (SMV). The new diagnostic will consist of PDV parts in a VISAR configuration. This configuration will enable the measurement of any velocity produced during shock physics experiments while the components used to build the diagnostic will give the diagnostic a fast rise time and make it easy to use. This thesis describes the process of building and testing the first single-mode VISAR. The tests include verifying the performance of the components and the diagnostic as a whole.

  16. SAMPEX Spin Stabilized Mode

    NASA Technical Reports Server (NTRS)

    Tsai, Dean C.; Markley, F. Landis; Watson, Todd P.

    2008-01-01

    The Solar, Anomalous, and Magnetospheric Particle Explorer (SAMPEX), the first of the Small Explorer series of spacecraft, was launched on July 3, 1992 into an 82' inclination orbit with an apogee of 670 km and a perigee of 520 km and a mission lifetime goal of 3 years. After more than 15 years of continuous operation, the reaction wheel began to fail on August 18,2007. With a set of three magnetic torquer bars being the only remaining attitude actuator, the SAMPEX recovery team decided to deviate from its original attitude control system design and put the spacecraft into a spin stabilized mode. The necessary operations had not been used for many years, which posed a challenge. However, on September 25, 2007, the spacecraft was successfully spun up to 1.0 rpm about its pitch axis, which points at the sun. This paper describes the diagnosis of the anomaly, the analysis of flight data, the simulation of the spacecraft dynamics, and the procedures used to recover the spacecraft to spin stabilized mode.

  17. Modes of fossil preservation

    USGS Publications Warehouse

    Schopf, J.M.

    1975-01-01

    The processes of geologic preservation are important for understanding the organisms represented by fossils. Some fossil differences are due to basic differences in organization of animals and plants, but the interpretation of fossils has also tended to be influenced by modes of preservation. Four modes of preservation generally can be distinguished: (1) Cellular permineralization ("petrifaction") preserves anatomical detail, and, occasionally, even cytologic structures. (2) Coalified compression, best illustrated by structures from coal but characteristic of many plant fossils in shale, preserves anatomical details in distorted form and produces surface replicas (impressions) on enclosing matrix. (3) Authigenic preservation replicates surface form or outline (molds and casts) prior to distortion by compression and, depending on cementation and timing, may intergrade with fossils that have been subject to compression. (4) Duripartic (hard part) preservation is characteristic of fossil skeletal remains, predominantly animal. Molds, pseudomorphs, or casts may form as bulk replacements following dissolution of the original fossil material, usually by leaching. Classification of the kinds of preservation in fossils will aid in identifying the processes responsible for modifying the fossil remains of both animals and plants. ?? 1975.

  18. A multi-mode multi-band RF receiver front-end for a TD-SCDMA/LTE/LTE-advanced in 0.18-μm CMOS process

    NASA Astrophysics Data System (ADS)

    Rui, Guo; Haiying, Zhang

    2012-09-01

    A fully integrated multi-mode multi-band directed-conversion radio frequency (RF) receiver front-end for a TD-SCDMA/LTE/LTE-advanced is presented. The front-end employs direct-conversion design, and consists of two differential tunable low noise amplifiers (LNA), a quadrature mixer, and two intermediate frequency (IF) amplifiers. The two independent tunable LNAs are used to cover all the four frequency bands, achieving sufficient low noise and high gain performance with low power consumption. Switched capacitor arrays perform a resonant frequency point calibration for the LNAs. The two LNAs are combined at the driver stage of the mixer, which employs a folded double balanced Gilbert structure, and utilizes PMOS transistors as local oscillator (LO) switches to reduce flicker noise. The front-end has three gain modes to obtain a higher dynamic range. Frequency band selection and mode of configuration is realized by an on-chip serial peripheral interface (SPI) module. The front-end is fabricated in a TSMC 0.18-μm RF CMOS process and occupies an area of 1.3 mm2. The measured double-sideband (DSB) noise figure is below 3.5 dB and the conversion gain is over 43 dB at all of the frequency bands. The total current consumption is 31 mA from a 1.8-V supply.

  19. The Aerosol Coarse Mode Initiative

    NASA Astrophysics Data System (ADS)

    Arnott, W. P.; Adhikari, N.; Air, D.; Kassianov, E.; Barnard, J.

    2014-12-01

    Many areas of the world show an aerosol volume distribution with a significant coarse mode and sometimes a dominant coarse mode. The large coarse mode is usually due to dust, but sea salt aerosol can also play an important role. However, in many field campaigns, the coarse mode tends to be ignored, because it is difficult to measure. This lack of measurements leads directly to a concomitant "lack of analysis" of this mode. Because, coarse mode aerosols can have significant effects on radiative forcing, both in the shortwave and longwave spectrum, the coarse mode -- and these forcings -- should be accounted for in atmospheric models. Forcings based only on fine mode aerosols have the potential to be misleading. In this paper we describe examples of large coarse modes that occur in areas of large aerosol loading (Mexico City, Barnard et al., 2010) as well as small loadings (Sacramento, CA; Kassianov et al., 2012; and Reno, NV). We then demonstrate that: (1) the coarse mode can contribute significantly to radiative forcing, relative to the fine mode, and (2) neglecting the coarse mode may result in poor comparisons between measurements and models. Next we describe -- in general terms -- the limitations of instrumentation to measure the coarse mode. Finally, we suggest a new initiative aimed at examining coarse mode aerosol generation mechanisms; transport and deposition; chemical composition; visible and thermal IR refractive indices; morphology; microphysical behavior when deposited on snow and ice; and specific instrumentation needs. Barnard, J. C., J. D. Fast, G. Paredes-Miranda, W. P. Arnott, and A. Laskin, 2010: Technical Note: Evaluation of the WRF-Chem "Aerosol Chemical to Aerosol Optical Properties" Module using data from the MILAGRO campaign, Atmospheric Chemistry and Physics, 10, 7325-7340. Kassianov, E. I., M. S. Pekour, and J. C. Barnard, 2012: Aerosols in Central California: Unexpectedly large contribution of coarse mode to aerosol radiative forcing

  20. LoComatioN: a software tool for the analysis of low copy number DNA profiles.

    PubMed

    Gill, Peter; Kirkham, Amanda; Curran, James

    2007-03-01

    Previously, the interpretation of low copy number (LCN) STR profiles has been carried out using the biological or 'consensus' method-essentially, alleles are not reported, unless duplicated in separate PCR analyses [P. Gill, J. Whitaker, C. Flaxman, N. Brown, J. Buckleton, An investigation of the rigor of interpretation rules for STRs derived from less than 100 pg of DNA, Forens. Sci. Int. 112 (2000) 17-40]. The method is now widely used throughout Europe. Although a probabilistic theory was simultaneously introduced, its time-consuming complexity meant that it could not be easily applied in practice. The 'consensus' method is not as efficient as the probabilistic approach, as the former wastes information in DNA profiles. However, the theory was subsequently extended to allow for DNA mixtures and population substructure in a programmed solution by Curran et al. [J.M. Curran, P. Gill, M.R. Bill, Interpretation of repeat measurement DNA evidence allowing for multiple contributors and population substructure, Forens. Sci. Int. 148 (2005) 47-53]. In this paper, we describe an expert interpretation system (LoComatioN) which removes this computational burden, and enables application of the full probabilistic method. This is the first expert system that can be used to rapidly evaluate numerous alternative explanations in a likelihood ratio approach, greatly facilitating court evaluation of the evidence. This would not be possible with manual calculation. Finally, the Gill et al. and Curran et al. papers both rely on the ability of the user to specify two quantities: the probability of allelic drop-out, and the probability of allelic contamination ("drop-in"). In this paper, we offer some guidelines on how these quantities may be specified. PMID:16759831

  1. Spark Ignition Characteristics of a LO2/LCH4 Engine at Altitude Conditions

    NASA Technical Reports Server (NTRS)

    Kleinhenz, Julie; Sarmiento, Charles; Marshall, William

    2012-01-01

    The use of non-toxic propellants in future exploration vehicles would enable safer, more cost effective mission scenarios. One promising "green" alternative to existing hypergols is liquid methane/liquid oxygen. To demonstrate performance and prove feasibility of this propellant combination, a 100lbf LO2/LCH4 engine was developed and tested under the NASA Propulsion and Cryogenic Advanced Development (PCAD) project. Since high ignition energy is a perceived drawback of this propellant combination, a test program was performed to explore ignition performance and reliability versus delivered spark energy. The sensitivity of ignition to spark timing and repetition rate was also examined. Three different exciter units were used with the engine's augmented (torch) igniter. Propellant temperature was also varied within the liquid range. Captured waveforms indicated spark behavior in hot fire conditions was inconsistent compared to the well-behaved dry sparks (in quiescent, room air). The escalating pressure and flow environment increases spark impedance and may at some point compromise an exciter.s ability to deliver a spark. Reduced spark energies of these sparks result in more erratic ignitions and adversely affect ignition probability. The timing of the sparks relative to the pressure/flow conditions also impacted the probability of ignition. Sparks occurring early in the flow could trigger ignition with energies as low as 1-6mJ, though multiple, similarly timed sparks of 55-75mJ were required for reliable ignition. An optimum time interval for spark application and ignition coincided with propellant introduction to the igniter and engine. Shifts of ignition timing were manifested by changes in the characteristics of the resulting ignition.

  2. Balm mint extract (Lo-701) for topical treatment of recurring herpes labialis.

    PubMed

    Koytchev, R; Alken, R G; Dundarov, S

    1999-10-01

    A double-blind, placebo-controlled, randomized trial was carried out with the aim of proving efficacy of standardized balm mint cream [active ingredient: 1% Lo-701--dried extract from Melissa officinalis L. leaves (70:1)] for the therapy of herpes simplex labialis. Sixty six patients with a history of recurrent herpes labialis (at least four episodes per year) in one center were treated topically; 34 of them with verum and 32 with placebo. The cream had to be smeared on the affected area four times daily over five days. A combined symptom score of the values for complaints, size of affected area and blisters at day 2 of therapy was formed as the primary target parameter. There was a significant difference in the values of the primary target parameter between both treatment groups: verum 4.03 +/- 0.33 (3.0); placebo 4.94 +/- 0.40 (5.0); values given are mean +/- SEM (median) of the symptoms score on day 2 of therapy. The tested formulation is effective for the treatment of herpes simplex labialis. The significant difference in the combined symptom score on the second day of treatment is of particular importance having in mind that the complaints in patients suffering from herpes labialis are usually most intensive at that time. In addition to the shortening of the healing period, the prevention of a spreading of the infection and the rapid effect on typical symptoms of herpes like itching, tingling, burning, stabbing, swelling, tautness and erythema, the balm mint cream has a further advantage. The different mechanism of action of the balm mint extract rules out the development of resistance of the herpes virus. Some indication exists that the intervals between the periods with herpes might be prolonged with balm mint cream treatment. PMID:10589440

  3. Nectary Structure and Nectar Secretion in Maxillaria coccinea (Jacq.) L.O. Williams ex Hodge (Orchidaceae)

    PubMed Central

    STPICZYŃSKA, M.; DAVIES, K. L.; GREGG, A.

    2004-01-01

    • Background and Aims It had previously been assumed that Maxillaria spp. produce no nectar. However, nectar has recently been observed in Maxillaria coccinea (Jacq.) L.O. Williams ex Hodge amongst other species. Furthermore, it is speculated that M. coccinea may be pollinated by hummingbirds. The aim of this paper is to investigate these claims further. • Methods Light microscopy, histochemistry, scanning and transmission electron microscopy. • Key Results This is the first detailed account of nectar secretion in Maxillaria Ruiz & Pav. A ‘faucet and sink’ arrangement occurs in M. coccinea. Here, the nectary is represented by a small protuberance upon the ventral surface of the column and nectar collects in a semi‐saccate reservoir formed by the fusion of the labellum and the base of the column‐foot. The nectary comprises a single‐layered epidermis and three or four layers of small subepidermal cells. Beneath these occur several layers of larger parenchyma cells. Epidermal cells lack ectodesmata and have a thin, permeable, reticulate cuticle with associated swellings that coincide with the middle lamella between adjoining epidermal cells. Nectar is thought to pass both along the apoplast and symplast and eventually through the stretched and distended cuticle. The secretory cells are collenchymatous, nucleated and have numerous pits with plasmodesmata, mitochondria, rough ER and plastids with many plastoglobuli but few lamellae. Subsecretory cells have fewer plastids than secretory cells. Nectary cells also contain large intravacuolar protein bodies. The floral morphology of M. coccinea is considered in relation to ornithophily and its nectary compared with a similar protuberance found in the entomophilous species M. parviflora (Poepp. & Endl.) Garay. • Conclusions Flowers of M. coccinea produce copious amounts of nectar and, despite the absence of field data, their morphology and the exact configuration of their parts argue strongly in favour of

  4. More food, low pollution (mo fo lo Po): a grand challenge for the 21st century.

    PubMed

    Davidson, Eric A; Suddick, Emma C; Rice, Charles W; Prokopy, Linda S

    2015-03-01

    Synthetic nitrogen fertilizer has been a double-edged sword, greatly improving human nutrition during the 20th century but also posing major human health and environmental challenges for the 21st century. In August 2013, about 160 agronomists, scientists, extension agents, crop advisors, economists, social scientists, farmers, representatives of regulatory agencies and nongovernmental organizations (NGOs), and other agricultural experts gathered to discuss the vexing challenge of how to produce more food to nourish a growing population while minimizing pollution to the environment. This collection of 14 papers authored by conference participants provides a much needed analysis of the many technical, economic, and social impediments to improving nitrogen use efficiency (NUE) in crop and animal production systems. These papers demonstrate that the goals of producing more food with low pollution (Mo Fo Lo Po) will not be achieved by technological developments alone but will also require policies that recognize the economic and social factors affecting farmer decision-making. Take-home lessons from this extraordinary interdisciplinary effort include the need (i) to develop partnerships among private and public sectors to demonstrate the most current, economically feasible, best management NUE practices at local and regional scales; (ii) to improve continuing education to private sector retailers and crop advisers; (iii) to tie nutrient management to performance-based indicators on the farm and in the downwind and downstream environment; and (iv) to restore investments in research, education, extension, and human resources that are essential for developing the interdisciplinary knowledge and innovative skills needed to achieve agricultural sustainability goals. PMID:26023950

  5. Dual-Mode Combustion

    NASA Technical Reports Server (NTRS)

    Goyne, Christopher P.; McDaniel, James C.

    2002-01-01

    The Department of Mechanical and Aerospace Engineering at the University of Virginia has conducted an investigation of the mixing and combustion processes in a hydrogen fueled dual-mode scramjet combustor. The experiment essentially consisted of the "direct connect" continuous operation of a Mach 2 rectangular combustor with a single unswept ramp fuel injector. The stagnation enthalpy of the test flow simulated a flight Mach number of 5. Measurements were obtained using conventional wall instrumentation and laser based diagnostics. These diagnostics included, pressure and wall temperature measurements, Fuel Plume Imaging (FPI) and Particle Image Velocimetry (PIV). A schematic of the combustor configuration and a summary of the measurements obtained are presented. The experimental work at UVa was parallel by Computational Fluid Dynamics (CFD) work at NASA Langley. The numerical and experiment results are compared in this document.

  6. Mixed Mode Matrix Multiplication

    SciTech Connect

    Meng-Shiou Wu; Srinivas Aluru; Ricky A. Kendall

    2004-09-30

    In modern clustering environments where the memory hierarchy has many layers (distributed memory, shared memory layer, cache,...), an important question is how to fully utilize all available resources and identify the most dominant layer in certain computations. When combining algorithms on all layers together, what would be the best method to get the best performance out of all the resources we have? Mixed mode programming model that uses thread programming on the shared memory layer and message passing programming on the distributed memory layer is a method that many researchers are using to utilize the memory resources. In this paper, they take an algorithmic approach that uses matrix multiplication as a tool to show how cache algorithms affect the performance of both shared memory and distributed memory algorithms. They show that with good underlying cache algorithm, overall performance is stable. When underlying cache algorithm is bad, superlinear speedup may occur, and an increasing number of threads may also improve performance.

  7. Estradiol agonists inhibit human LoVo colorectal-cancer cell proliferation and migration through p53

    PubMed Central

    Hsu, Hsi-Hsien; Kuo, Wei-Wen; Ju, Da-Tong; Yeh, Yu-Lan; Tu, Chuan-Chou; Tsai, Ying-Lan; Shen, Chia-Yao; Chang, Sheng-Huang; Chung, Li-Chin; Huang, Chih-Yang

    2014-01-01

    AIM: To investigate the effects of 17β-estradiol via estrogen receptors (ER) or direct administration of ER agonists on human colorectal cancer. METHODS: LoVo cells were established from the Bioresource Collection and Research Center and cultured in phenol red-free DMEM (Sigma, United States). To investigate the effects of E2 and/or ER selective agonists on cellular proliferation, LoVo colorectal cells were treated with E2 or ER-selective agonists for 24 h and 48 h and subjected to the MTT (Sigma) assay to find the concentration. And investigate the effects of E2 and/or ER selective agonists on cell used western immunoblotting to find out the diversification of signaling pathways. In order to observe motility and migration the wound healing assay and a transwell chamber (Neuro Probe) plate were tased. For a quantitative measure, we counted the number of migrating cells to the wound area post-wounding for 24 h. We further examined the cellular migration-regulating factors urokinase-type plasminogen activator (u-PA), tissue-type plasminogen activator (t-PA) and matrix metalloproteinase (MMP)-9 in human LoVo cells so gelatin zymography that we used and gelatinolytic activity was visualized by Coomassie blue staining. And these results are presented as means ± SE, and statistical comparisons were made using Student’s t-test. RESULTS: The structure was first compared with E2 and ER agonists. We then treated the LoVo cells with E2 and ER agonists (10-8 mol/L) for 24 h and 48 h and subsequently measured the cell viability using MTT assay. Our results showed that treatment with 17β-estradiol and/or ER agonists in human LoVo colorectal cancer cells activated p53 and then up-regulated p21 and p27 protein levels, subsequently inhibiting the downstream target gene, cyclin D1, which regulates cell proliferation. Taken together, our findings demonstrate the anti-tumorigenesis effects of 17β-estradiol and/or ER agonists and suggest that these compounds may prove to be a

  8. Tunable asymmetric mode conversion using the dark-mode of three-mode waveguide system.

    PubMed

    Kim, Joonsoo; Lee, Seung-Yeol; Lee, Yohan; Kim, Hwi; Lee, Byoungho

    2014-11-17

    A design scheme for low-reflection asymmetric mode conversion structure in three-mode waveguide system is proposed. By using a dark-mode of three-mode system, which can be interpreted in terms of destructive interference of transition amplitudes, the transmission characteristics for forward and backward directions can be designed separately. After explanation of the proposed design scheme, we demonstrate an example of asymmetric mode converter that consists of two gratings. The proposed scheme may be useful for the design of tunable asymmetric transmission devices due to its design flexibility and efficient design process. PMID:25402109

  9. The Integrated Mode Management Interface

    NASA Technical Reports Server (NTRS)

    Hutchins, Edwin

    1996-01-01

    Mode management is the processes of understanding the character and consequences of autoflight modes, planning and selecting the engagement, disengagement and transitions between modes, and anticipating automatic mode transitions made by the autoflight system itself. The state of the art is represented by the latest designs produced by each of the major airframe manufacturers, the Boeing 747-400, the Boeing 777, the McDonnell Douglas MD-11, and the Airbus A320/A340 family of airplanes. In these airplanes autoflight modes are selected by manipulating switches on the control panel. The state of the autoflight system is displayed on the flight mode annunciators. The integrated mode management interface (IMMI) is a graphical interface to autoflight mode management systems for aircraft equipped with flight management computer systems (FMCS). The interface consists of a vertical mode manager and a lateral mode manager. Autoflight modes are depicted by icons on a graphical display. Mode selection is accomplished by touching (or mousing) the appropriate icon. The IMMI provides flight crews with an integrated interface to autoflight systems for aircraft equipped with flight management computer systems (FMCS). The current version is modeled on the Boeing glass-cockpit airplanes (747-400, 757/767). It runs on the SGI Indigo workstation. A working prototype of this graphics-based crew interface to the autoflight mode management tasks of glass cockpit airplanes has been installed in the Advanced Concepts Flight Simulator of the CSSRF of NASA Ames Research Center. This IMMI replaces the devices in FMCS equipped airplanes currently known as mode control panel (Boeing), flight guidance control panel (McDonnell Douglas), and flight control unit (Airbus). It also augments the functions of the flight mode annunciators. All glass cockpit airplanes are sufficiently similar that the IMMI could be tailored to the mode management system of any modern cockpit. The IMMI does not replace the

  10. Optimization of few-mode-fiber based mode converter for mode division multiplexing transmission

    NASA Astrophysics Data System (ADS)

    Xie, Yiwei; Fu, Songnian; Zhang, Minming; Tang, M.; Shum, P.; Liu, Deming

    2013-10-01

    Few-mode-fiber (FMF) based mode division multiplexing (MDM) is a promising technique to further increase the transmission capacity of single mode fibers. We propose and numerically investigate a fiber-optical mode converter (MC) using long period gratings (LPGs) fabricated on the FMF by point-by-point CO2 laser inscription technique. In order to precisely excite three modes (LP01, LP11, and LP02), both untilted LPG and tilted LPG are comprehensively optimized through the length, index modulation depth, and tilt angle of the LPG in order to achieve a mode contrast ratio (MCR) of more than 20 dB with less wavelength dependence. It is found that the proposed MCs have obvious advantages of high MCR, low mode crosstalk, easy fabrication and maintenance, and compact size.

  11. Volatile organic compound fluxes and concentrations in London (ClearfLo)

    NASA Astrophysics Data System (ADS)

    Valach, Amy; Langford, Ben; Nemitz, Eiko; MacKenzie, Rob; Hewitt, Nick

    2014-05-01

    Volatile organic compounds (VOCs) from anthropogenic sources such as fuel combustion or evaporative emissions can directly and indirectly affect human health. Some VOCs, such as benzene and 1,3- butadiene are carcinogens. These and other VOCs contribute to the formation of ozone (O3) and aerosol particles, which have effects on human health and the radiative balance of the atmosphere. Although in the UK VOC emissions are subject to control under European Commission Directive 2008/50/EC and emission reducing technologies have been implemented, urban air pollution remains a concern. Urban air quality is likely to remain a priority since currently >50% of the global population live in urban areas with trends in urbanization and population migration predicted to increase. The ClearfLo project is a large multi-institutional consortium funded by the UK Natural Environment Research Council (NERC) and provides integrated measurements of meteorology, gas phase and particulate composition of the atmosphere over London. Both long term and IOP measurements were made at street and elevated locations at a range of sites across London and its surroundings during 2011 and 2012. Mixing ratios of a selection of nine VOCs were measured using a high sensitivity proton transfer reaction-mass spectrometer (PTR-MS) at a ground level urban background (North Kensington) and kerbside (Marylebone Road) site during the winter IOP. VOC fluxes were measured by virtually disjunct eddy covariance (vDEC) at an elevated urban site (King's College Strand) in Aug-Dec 2012. Our results for the first IOP showed that most of the selected compound concentrations depended on traffic emissions, although there was a marked difference between the urban background and kerbside sites. We identified some temperature effects on VOC concentrations. We also present the first analyses of VOC flux measurements over London. Preliminary analyses indicate most compounds associated with vehicle emissions closely

  12. Mitigation of mode instabilities by dynamic excitation of fiber modes

    NASA Astrophysics Data System (ADS)

    Otto, Hans-Jürgen; Jauregui, Cesar; Stutzki, Fabian; Jansen, Florian; Limpert, Jens; Tünnermann, Andreas

    2013-03-01

    By dynamically varying the power content of the excited fiber modes of the main amplifier of a fiber-based MOPA system at high average output power levels, it was possible to mitigate mode instabilities to a large extent. In order to achieve the excitation variation, we used an acousto-optic deflector in front of the Yb-doped rod-type fiber. Therewith, it was possible to significantly increase both the average and the instantaneous minimum power content of the fundamental mode. This, consequently, led to a substantial improvement of the beam quality and pointing stability at power levels well beyond the threshold of mode instabilities.

  13. On the propagation and mode conversion of auroral medium frequency bursts

    NASA Astrophysics Data System (ADS)

    Broughton, M. C.; LaBelle, J.; Kim, E.-H.; Yoon, P. H.; Johnson, J. R.; Cairns, I. H.

    2016-02-01

    Auroral medium frequency (MF) bursts are broadband, impulsive radio emissions associated with local substorm onsets. MF bursts consist of a characteristic fine structure whereby the higher frequencies arrive 10-100 ms before the lower frequencies. LaBelle (2011a) proposed that MF bursts originate as Langmuir/Z mode waves on the topside of the ionosphere that mode-convert to LO mode waves and propagate to ground level, with the fine structure resulting by propagation delays due to the topside ionospheric density profile. We investigate three aspects of this mechanism. First, full-wave calculations are used to simulate the MF burst fine structure using a realistic ionospheric density profile. The delay between the highest and lowest frequencies is 21 ms. This value is smaller than the experimentally determined delays of ˜100 ms presented in Bunch and LaBelle (2009), but differences between the topside electron number density profile used in the simulations and the number density profile during disturbed conditions make comparisons only approximate. Second, the Landau damping of Langmuir/Z mode waves on the topside ionosphere is calculated, assuming the electron distribution function consists of a cold background population (ne0) and a warm secondary population (nse). The Landau damping is small when nse/ne0 = 0.04% (consistent with Maggs and Lotko (1981)) but is significant when nse/ne0 > 0.4%. Finally, full-wave calculations are used to determine the mode conversion efficiency from Langmuir/Z mode waves to LO mode waves. These imply that waves would suffer an attenuation of wave energy density of approximately 5-10% if they are generated with their wave vectors in a narrow cone centered around the local magnetic field. Taken together, these calculations suggest that for small values of nse/ne0 <0.4%, the mechanism proposed by LaBelle (2011a) is a plausible explanation for the origin of MF bursts.

  14. Automatic determination of important mode-mode correlations in many-mode vibrational wave functions

    NASA Astrophysics Data System (ADS)

    König, Carolin; Christiansen, Ove

    2015-04-01

    We introduce new automatic procedures for parameterizing vibrational coupled cluster (VCC) and vibrational configuration interaction wave functions. Importance measures for individual mode combinations in the wave function are derived based on upper bounds to Hamiltonian matrix elements and/or the size of perturbative corrections derived in the framework of VCC. With a threshold, this enables an automatic, system-adapted way of choosing which mode-mode correlations are explicitly parameterized in the many-mode wave function. The effect of different importance measures and thresholds is investigated for zero-point energies and infrared spectra for formaldehyde and furan. Furthermore, the direct link between important mode-mode correlations and coordinates is illustrated employing water clusters as examples: Using optimized coordinates, a larger number of mode combinations can be neglected in the correlated many-mode vibrational wave function than with normal coordinates for the same accuracy. Moreover, the fraction of important mode-mode correlations compared to the total number of correlations decreases with system size. This underlines the potential gain in efficiency when using optimized coordinates in combination with a flexible scheme for choosing the mode-mode correlations included in the parameterization of the correlated many-mode vibrational wave function. All in all, it is found that the introduced schemes for parameterizing correlated many-mode vibrational wave functions lead to at least as systematic and accurate calculations as those using more standard and straightforward excitation level definitions. This new way of defining approximate calculations offers potential for future calculations on larger systems.

  15. Control of neoclassical tearing modes

    NASA Astrophysics Data System (ADS)

    Maraschek, M.

    2012-07-01

    Neoclassically driven tearing modes (NTMs) are a major problem for tokamaks operating in a conventional ELMy H-mode scenario. Depending on the mode numbers these pressure-driven perturbations cause a mild reduction in the maximum achievable βN = βt/(Ip/aBt) before the onset of the NTM, or can even lead to disruptions at a low edge safety factor, q95. A control of these types of modes in high βN plasmas is therefore of vital interest for magnetically confined fusion plasmas. The control consists of two major approaches, namely the control of the excitation of these modes and the removal, or at least mitigation, of these modes, once an excitation could not be avoided. For both routes examples will be given and the applicability of these approaches to ITER will be discussed.

  16. Waveguides having patterned, flattened modes

    DOEpatents

    Messerly, Michael J.; Pax, Paul H.; Dawson, Jay W.

    2015-10-27

    Field-flattening strands may be added to and arbitrarily positioned within a field-flattening shell to create a waveguide that supports a patterned, flattened mode. Patterning does not alter the effective index or flattened nature of the mode, but does alter the characteristics of other modes. Compared to a telecom fiber, a hexagonal pattern of strands allows for a three-fold increase in the flattened mode's area without reducing the separation between its effective index and that of its bend-coupled mode. Hexagonal strand and shell elements prove to be a reasonable approximation, and, thus, to be of practical benefit vis-a-vis fabrication, to those of circular cross section. Patterned flattened modes offer a new and valuable path to power scaling.

  17. The normal modes of lattice vibrations of ice XI

    PubMed Central

    Zhang, Peng; Wang, Zhe; Lu, Ying-Bo; Ding, Zheng-Wen

    2016-01-01

    The vibrational spectrum of ice XI at thermal wavelengths using the CASTEP code, a first-principles simulation method, is investigated. A dual-track approach is constructed to verify the validity for the computational phonon spectrum: collate the simulated spectrum with inelastic neutron scattering experiments and assign the photon scattering peaks according to the calculated normal vibration frequencies. The 33 optical normal vibrations at the Brillouin center are illustrated definitely from the ab initio outcomes. The depolarizing field effect of the hydrogen bond vibrations at frequencies of 229 cm−1 and 310 cm−1 is found to agree well with the LST relationship. It is a convincing evidence to manifest the LO-TO splitting of hydrogen bonds in ice crystal. We attribute the two hydrogen bond peaks to the depolarization effect and apply this viewpoint to ordinary ice phase, ice Ih, which is difficult to analyse their vibration modes due to proton disorder. PMID:27375199

  18. The normal modes of lattice vibrations of ice XI

    NASA Astrophysics Data System (ADS)

    Zhang, Peng; Wang, Zhe; Lu, Ying-Bo; Ding, Zheng-Wen

    2016-07-01

    The vibrational spectrum of ice XI at thermal wavelengths using the CASTEP code, a first-principles simulation method, is investigated. A dual-track approach is constructed to verify the validity for the computational phonon spectrum: collate the simulated spectrum with inelastic neutron scattering experiments and assign the photon scattering peaks according to the calculated normal vibration frequencies. The 33 optical normal vibrations at the Brillouin center are illustrated definitely from the ab initio outcomes. The depolarizing field effect of the hydrogen bond vibrations at frequencies of 229 cm‑1 and 310 cm‑1 is found to agree well with the LST relationship. It is a convincing evidence to manifest the LO-TO splitting of hydrogen bonds in ice crystal. We attribute the two hydrogen bond peaks to the depolarization effect and apply this viewpoint to ordinary ice phase, ice Ih, which is difficult to analyse their vibration modes due to proton disorder.

  19. The normal modes of lattice vibrations of ice XI.

    PubMed

    Zhang, Peng; Wang, Zhe; Lu, Ying-Bo; Ding, Zheng-Wen

    2016-01-01

    The vibrational spectrum of ice XI at thermal wavelengths using the CASTEP code, a first-principles simulation method, is investigated. A dual-track approach is constructed to verify the validity for the computational phonon spectrum: collate the simulated spectrum with inelastic neutron scattering experiments and assign the photon scattering peaks according to the calculated normal vibration frequencies. The 33 optical normal vibrations at the Brillouin center are illustrated definitely from the ab initio outcomes. The depolarizing field effect of the hydrogen bond vibrations at frequencies of 229 cm(-1) and 310 cm(-1) is found to agree well with the LST relationship. It is a convincing evidence to manifest the LO-TO splitting of hydrogen bonds in ice crystal. We attribute the two hydrogen bond peaks to the depolarization effect and apply this viewpoint to ordinary ice phase, ice Ih, which is difficult to analyse their vibration modes due to proton disorder. PMID:27375199

  20. 100-Lb(f) LO2/LCH4 Reaction Control Engine Technology Development for Future Space Vehicles

    NASA Technical Reports Server (NTRS)

    Robinson, Philip J.; Veith, Eric M.; Hurlbert, Eric A.; Jimenez, Rafael; Smith, Timothy D.

    2008-01-01

    The National Aeronautics and Space Administration (NASA) has identified liquid oxygen (LO2)/liquid methane (LCH4) propulsion systems as promising options for some future space vehicles. NASA issued a contract to Aerojet to develop a 100-lbf (445 N) LO2/LCH4 Reaction Control Engine (RCE) aimed at reducing the risk of utilizing a cryogenic reaction control system (RCS) on a space vehicle. Aerojet utilized innovative design solutions to develop an RCE that can ignite reliably over a broad range of inlet temperatures, perform short minimum impulse bits (MIB) at small electrical pulse widths (EPW), and produce excellent specific impulse (Isp) across a range of engine mixture ratios (MR). These design innovations also provide a start transient with a benign MR, ensuring good thrust chamber compatibility and long life. In addition, this RCE can successfully operate at MRs associated with main engines, enabling the RCE to provide emergency backup propulsion to minimize vehicle propellant load and overall system mass.

  1. Single mode acoustic fiber waveguide

    NASA Technical Reports Server (NTRS)

    Jackson, B. S.; May, R. G.; Claus, R. O.

    1984-01-01

    The single mode operation of a clad rod acoustic waveguide is described. Unlike conventional clad optical and acoustic waveguiding structures which use modes confined to a central core surrounded by a cladding, this guide supports neither core nor cladding modes but a single interface wave field on the core-cladding boundary. The propagation of this bound field and the potential improved freedom from spurious responses is discussed.

  2. Mode statistics in random lasers

    SciTech Connect

    Zaitsev, Oleg

    2006-12-15

    Representing an ensemble of random lasers with an ensemble of random matrices, we compute the average number of lasing modes and its fluctuations. The regimes of weak and strong coupling of the passive resonator to the environment are considered. In the latter case, contrary to an earlier claim in the literature, we do not find a power-law dependence of the average mode number on the pump strength. For the relative fluctuations, however, a power law can be established. It is shown that, due to the mode competition, the distribution of the number of excited modes over an ensemble of lasers is not binomial.

  3. Facing rim cavities fluctuation modes

    NASA Astrophysics Data System (ADS)

    Casalino, Damiano; Ribeiro, André F. P.; Fares, Ehab

    2014-06-01

    Cavity modes taking place in the rims of two opposite wheels are investigated through Lattice-Boltzmann CFD simulations. Based on previous observations carried out by the authors during the BANC-II/LAGOON landing gear aeroacoustic study, a resonance mode can take place in the volume between the wheels of a two-wheel landing gear, involving a coupling between shear-layer vortical fluctuations and acoustic modes resulting from the combination of round cavity modes and wheel-to-wheel transversal acoustic modes. As a result, side force fluctuations and tonal noise side radiation take place. A parametric study of the cavity mode properties is carried out in the present work by varying the distance between the wheels. Moreover, the effects due to the presence of the axle are investigated by removing the axle from the two-wheel assembly. The azimuthal properties of the modes are scrutinized by filtering the unsteady flow in narrow bands around the tonal frequencies and investigating the azimuthal structure of the filtered fluctuation modes. Estimation of the tone frequencies with an ad hoc proposed analytical formula confirms the observed modal properties of the filtered unsteady flow solutions. The present study constitutes a primary step in the description of facing rim cavity modes as a possible source of landing gear tonal noise.

  4. Methods of component mode synthesis

    NASA Technical Reports Server (NTRS)

    Craig, R. R., Jr.

    1977-01-01

    A generalized substructure coupling, or component mode synthesis, procedure is described. Specific methods, applications, and such special topics as damping and experimental verification are surveyed.

  5. Enhancement of the HIF-1α/15-LO/15-HETE Axis Promotes Hypoxia-Induced Endothelial Proliferation in Preeclamptic Pregnancy

    PubMed Central

    Liu, Qian; Zhang, Yanhua; Li, Huiying; Li, Peiling; Zhu, Daling

    2014-01-01

    Preeclampsia (PE) is an extremely serious condition in pregnant women and the leading cause of maternal and fetal morbidity and mortality. Despite active research, the etiological factors of this disorder remain elusive. The increased release of 15-hydroxyeicosatetraenoic acid (15-HETE) in the placenta of preeclamptic patients has been studied, but its exact role in PE pathogenesis remains unknown. Mounting evidence shows that PE is associated with placental hypoxia, impaired placental angiogenesis, and endothelial dysfunction. In this study, we confirmed the upregulated expression of hypoxia-inducible factor 1α (HIF-1α) and 15-lipoxygenase-1/2 (15-LO-1/2) in patients with PE. Production of the arachidonic acid metabolite, 15-HETE, also increased in the preeclamptic placenta, which suggests enhanced activation of the HIF-1α–15-LO–15-HETE axis. Furthermore, this study is the first to show that the umbilical cord of preeclamptic women contains significantly higher serum concentrations of 15-HETE than that of healthy pregnant women. The results also show that expression of 15-LO-1/2 is upregulated in both human umbilical vein endothelial cells (HUVECs) collected from preeclamptic women and in those cultured under hypoxic conditions. Exogenous 15-HETE promotes the migration of HUVECs and in vitro tube formation and promotes cell cycle progression from the G0/G1 phase to the G2/M + S phase, whereas the 15-LO inhibitor, NDGA, suppresses these effects. The HIF-1α/15-LO/15-HETE pathway is therefore significantly associated within the pathology of PE. PMID:24796548

  6. Rosiglitazone-induced CD36 up-regulation resolves inflammation by PPARγ and 5-LO-dependent pathways.

    PubMed

    Ballesteros, Iván; Cuartero, María I; Pradillo, Jesús M; de la Parra, Juan; Pérez-Ruiz, Alberto; Corbí, Angel; Ricote, Mercedes; Hamilton, John A; Sobrado, Mónica; Vivancos, José; Nombela, Florentino; Lizasoain, Ignacio; Moro, María A

    2014-04-01

    PPARγ-achieved neuroprotection in experimental stroke has been explained by the inhibition of inflammatory genes, an action in which 5-LO, Alox5, is involved. In addition, PPARγ is known to promote the expression of CD36, a scavenger receptor that binds lipoproteins and mediates bacterial recognition and also phagocytosis. As phagocytic clearance of neutrophils is a requisite for resolution of the inflammatory response, PPARγ-induced CD36 expression might help to limit inflammatory tissue injury in stroke, an effect in which 5-LO might also be involved. Homogenates, sections, and cellular suspensions were prepared from brains of WT and Alox5(-/-) mice exposed to distal pMCAO. BMMs were obtained from Lys-M Cre(+) PPARγ(f/f) and Lys-M Cre(-) PPARγ(f/f) mice. Stereological counting of double-immunofluorescence-labeled brain sections and FACS analysis of cell suspensions was performed. In vivo and in vitro phagocytosis of neutrophils by microglia/macrophages was analyzed. PPARγ activation with RSG induced CD36 expression in resident microglia. This process was mediated by the 5-LO gene, which is induced in neurons by PPARγ activation and at least by one of its products--LXA4--which induced CD36 independently of PPARγ. Moreover, CD36 expression helped resolution of inflammation through phagocytosis, concomitantly to neuroprotection. Based on these findings, in addition to a direct modulation by PPARγ, we propose in brain a paracrine model by which products generated by neuronal 5-LO, such as LXA4, increase the microglial expression of CD36 and promote tissue repair in pathologies with an inflammatory component, such as stroke. PMID:24338629

  7. Immune Reconstitution after Autologous Hematopoietic Transplantation with Lin−, CD34+, Thy-1LO Selected or Intact Stem Cell Products*

    PubMed Central

    Singh, Rakesh K.; Varney, Michelle L.; Leutzinger, Cheryl; Vose, Julie M.; Bierman, Philip J.; Buyukberber, Suleyman; Ino, Kazuhiko; Loh, Kevin; Nichols, Craig; Inwards, David; Rifkin, Robert; Talmadge, James E.

    2007-01-01

    In sequential studies, we compared immune reconstitution following high dose chemotherapy (HDT) and stem cell transplantation (SCT) using intact mobilized peripheral blood stem cell (PSC) in intermediate grade non-Hodgkin's lymphoma (NHL) patients and CD34+, lineage negative (Lin−), Thy-1lo (CD34+Lin−Thy-1lo) stem cells in low-grade NHL patients. Cytokine expression and cellular phenotype and function were used as the basis for comparison. Despite differences in cellular composition of the stem cell grafts, immune reconstitution in both groups was similar. Significantly higher levels of type 1 and 2-associated cytokine messenger ribonucleic acid (mRNA) were observed both prior to and following transplant in the peripheral blood (PB) of both cohorts as compared to normal individuals. Similar levels of interleukin (IL)-4, IL-10, interferon-gamma (IFN-γ), and tumor necrosis factor-alpha (TNF-α) mRNA were seen in PB mononuclear cells following transplant with either product. In contrast, patients receiving isolated CD34+Lin−Thy-1lo cells expressed significantly higher IL-2 levels at all times examined post-transplant. Despite the high levels of cytokine gene expression and rapid restoration to pretransplant levels of CD3 cell number by day 30, T cell function and CD4:CD8 and CD4+CD45RA:CD4+CD45RO+ ratios were significantly depressed in both cohorts compared to normal donors, and significantly lower in patients transplanted with CD34+Lin−Thy-1lo compared to patients receiving an intact PSC product. These data suggest that the peripheral tolerance in patients receiving HDT and an autologous SCT occurs independent of graft composition, although immune function and CD4 recovery is better facilitated by transplantation of an intact product. PMID:17570320

  8. Ultrasonic Doppler Modes

    NASA Astrophysics Data System (ADS)

    Tortoli, Piero; Fidanzati, Paolo; Luca, Bassi

    Any US equipment includes Doppler facilities capable of providing information about moving structures inside the human body. In most cases, the primary interest is in the investigation of blood flow dynamics, since this may be helpful for early diagnosis of cardiovascular diseases. However, there is also an increasing interest in tracking the movements of human tissues, since such movements can give an indirect evaluation of their elastic properties, which are valuable indicators of the possible presence of pathologies. This paper aims at presenting an overview of the different ways in which the Doppler technique has been developed and used in medical ultrasound (US), from early continuous wave (CW) systems to advanced pulsed wave (PW) colour-Doppler equipment. In particular, the most important technical features and clinical applications of CW, single-gate PW, multi-gate PW and flow-imaging systems are reviewed. The main signal processing approaches used for detection of Doppler frequencies are described, including time-domain and frequency-domain (spectral) methods, as well as novel strategies like, e.g., harmonic Doppler mode, which have been recently introduced to exploit the benefits of US contrast agents.

  9. Whispering gallery mode sensors

    PubMed Central

    Foreman, Matthew R.; Swaim, Jon D.; Vollmer, Frank

    2015-01-01

    We present a comprehensive overview of sensor technology exploiting optical whispering gallery mode (WGM) resonances. After a short introduction we begin by detailing the fundamental principles and theory of WGMs in optical microcavities and the transduction mechanisms frequently employed for sensing purposes. Key recent theoretical contributions to the modeling and analysis of WGM systems are highlighted. Subsequently we review the state of the art of WGM sensors by outlining efforts made to date to improve current detection limits. Proposals in this vein are numerous and range, for example, from plasmonic enhancements and active cavities to hybrid optomechanical sensors, which are already working in the shot noise limited regime. In parallel to furthering WGM sensitivity, efforts to improve the time resolution are beginning to emerge. We therefore summarize the techniques being pursued in this vein. Ultimately WGM sensors aim for real-world applications, such as measurements of force and temperature, or alternatively gas and biosensing. Each such application is thus reviewed in turn, and important achievements are discussed. Finally, we adopt a more forward-looking perspective and discuss the outlook of WGM sensors within both a physical and biological context and consider how they may yet push the detection envelope further. PMID:26973759

  10. HMD cueing mode degradation

    NASA Astrophysics Data System (ADS)

    Speck, Richard P.; Fidopiastis, Cali M.; Herz, Norman E., Jr.

    2003-09-01

    Pilot cueing is a valuable use of Head Mounted Displays (HMDs) as it greatly helps the user to visually locate electronically identified targets. It is well known that a target which is hard to spot in the sky can be easily tracked and studied after it has been visually located. Transients, including sun glint, can reveal much about distant targets as they are visually studied. This is implicit in the "Visual Rules of Engagement". The term "Virtual Beyond Visual Range" has been coined to reflect the fact that optimized HMD cueing can extend visual identification to ranges previously covered only by radar data. The visual acquisition range can drop by a factor of three, however, when HMD image correlation errors expand the uncertainty zone a pilot must visually search. We have demonstrated that system errors, tolerable for off axis missile targeting, can produce this large drop in operational effectiveness. Studies using the Spectron SE1430 HMD analysis system have shown that errors of this magnitude can develop in current HMD models, and that these errors were neither identified by "ready room" tests nor were they correctable in the cockpit. The focus of this study was to develop affordable techniques to quantify the relationship of combat effectiveness to HMD defects for this and other advanced operating modes. When combined with field monitoring of HMD degradation, this makes economic optimization of the HMD supply/maintenance model possible while fulfilling operational mission requirements.

  11. 77 FR 6793 - D'Lo Gas Storage, LLC; Notice of Intent To Prepare an Environmental Assessment for the PROPOSED D...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-09

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF ENERGY Federal Energy Regulatory Commission D'Lo Gas Storage, LLC; Notice of Intent To Prepare an Environmental Assessment for the PROPOSED D'LO Gas Storage Project, Request for Comments on Environmental Issues, and Notice of Onsite Environmental Review...

  12. A Study of the Relationship between Levels of Technology Implementation (LoTi) and Student Performance on Texas Assessment of Knowledge and Skills (TAKS) Scores

    ERIC Educational Resources Information Center

    Berkeley-Jones, Catherine Spotswood

    2012-01-01

    The purpose of this study was to examine teacher Levels of Technology Implementation (LoTi) self-ratings and student Texas Assessment of Knowledge and Skills (TAKS) scores. The study assessed the relationship between LoTi ratings and TAKS scores of 6th, 7th, and 8th grade students as reported in student records at Alamo Heights Independent School…

  13. Single mode optofluidic distributed feedback dye laser

    NASA Astrophysics Data System (ADS)

    Li, Zhenyu; Zhang, Zhaoyu; Emery, Teresa; Scherer, Axel; Psaltis, Demetri

    2006-01-01

    Single frequency lasing from organic dye solutions on a monolithic poly(dimethylsiloxane) (PDMS) elastomer chip is demonstrated. The laser cavity consists of a single mode liquid core/PDMS cladding channel waveguide and a phase shifted 15th order distributed feedback (DFB) structure. A 1mM solution of Rhodamine 6G in a methanol and ethylene glycol mixture was used as the gain medium. Using 6 nanosecond 532nm Nd:YAG laser pulses as the pump light, we achieved threshold pump fluence of ~0.8mJ/cm2 and single-mode operation at pump levels up to ten times the threshold. This microfabricated dye laser provides a compact and inexpensive coherent light source for microfluidics and integrated optics covering from near UV to near IR spectral region.

  14. Nonlinear mode coupling in whispering-gallery-mode resonators

    NASA Astrophysics Data System (ADS)

    D'Aguanno, Giuseppe; Menyuk, Curtis R.

    2016-04-01

    We present a first-principles derivation of the coupled nonlinear Schrödinger equations that govern the interaction between two families of modes with different transverse profiles in a generic whispering-gallery-mode resonator. We find regions of modulational instability and the existence of trains of bright solitons in both the normal and the anomalous dispersion regime.

  15. The Host Galaxies of LoBAL QSOs at Low z: A Perspective from HST UVIS Images

    NASA Astrophysics Data System (ADS)

    Behn, Wyatt Alan; Lazarova, Mariana; Canalizo, Gabriela

    2016-06-01

    We present GALFIT models of a complete optically-selected volume-limited sample of Low-Ionization Broad Absorption Line QSOs (LoBALs) in the redshift range 0.5-0.6 observed with HST WFC3 UVIS F475W. We investigate the morphologies in the rest frame u which map the younger stellar populations. In addition, we present statistics on the number of neighborhood galaxies within 150 kpc and possible trends between clustering and host galaxy properties. This sample of LoBALs is selected from QSOs characterized by their extreme blue-shifted absorption in the Mg II line—which is a signature of high velocity winds towards the observer. Only ~1-3% of optically selected QSOs are LoBALs. Their low fraction could be explained by their orientation or by a short period of outflow manifest in all QSOs during their lifetime. We aim to better understand the possibility of the evolutionary model by studying their morphologies in detail. Previous work on this sample, from images with F125W filter (rest frame i), shows that at least 60% of these objects exhibit signs of recent merger activity. We complement those results with our results from the UVIS observations and neighborhood clustering statistics.

  16. Lava bubble-wall fragments formed by submarine hydrovolcanic explosions on Lo'ihi Seamount and Kilauea Volcano

    USGS Publications Warehouse

    Clague, D.A.; Davis, A.S.; Bischoff, J.L.; Dixon, J.E.; Geyer, R.

    2000-01-01

    Glassy bubble-wall fragments, morphologically similar to littoral limu o Pele, have been found in volcanic sands erupted on Lo'ihi Seamount and along the submarine east rift zone of Kilauea Volcano. The limu o Pele fragments are undegassed with respect to H2O and S and formed by mild steam explosions. Angular glass sand fragments apparently form at similar, and greater, depths by cooling-contraction granulation. The limu o Pele fragments from Lo'ihi Seamount are dominantly tholeiitic basalt containing 6.25-7.25% MgO. None of the limu o Pele samples from Lo'ihi Seamount contains less than 5.57% MgO, suggesting that higher viscosity magmas do not form lava bubbles. The dissolved CO2 and H2O contents of 7 of the limu o Pele fragments indicate eruption at 1200??300 m depth (120??30 bar). These pressures exceed that generally thought to limit steam explosions. We conclude that hydrovolcanic eruptions are possible, with appropriate pre-mixing conditions, at pressures as great as 120 bar.

  17. Three dimensional HiLo-based structured illumination for a digital scanned laser sheet microscopy (DSLM) in thick tissue imaging

    PubMed Central

    Bhattacharya, Dipanjan; Singh, Vijay Raj; Zhi, Chen; So, Peter T. C.; Matsudaira, Paul; Barbastathis, George

    2012-01-01

    Laser sheet based microscopy has become widely accepted as an effective active illumination method for real time three-dimensional (3D) imaging of biological tissue samples. The light sheet geometry, where the camera is oriented perpendicular to the sheet itself, provides an effective method of eliminating some of the scattered light and minimizing the sample exposure to radiation. However, residual background noise still remains, limiting the contrast and visibility of potentially interesting features in the samples. In this article, we investigate additional structuring of the illumination for improved background rejection, and propose a new technique, “3D HiLo” where we combine two HiLo images processed from orthogonal directions to improve the condition of the 3D reconstruction. We present a comparative study of conventional structured illumination based demodulation methods, namely 3Phase and HiLo with a newly implemented 3D HiLo approach and demonstrate that the latter yields superior signal-to-background ratio in both lateral and axial dimensions, while simultaneously suppressing image processing artifacts. PMID:23262684

  18. Mode Launcher Design for the Multi-moded DLDS

    SciTech Connect

    Li, Zenghai

    2003-04-30

    The DLDS (Delay Line Distribution System) power delivery system proposed by KEK combines several klystrons to obtain the high peak power required to drive a TeV scale linear collider. In this system the combined klystron output is subdivided into shorter pulses by proper phasing of the sources, and each subpulse is delivered to various accelerator sections via separate waveguides. A cost-saving improvement suggested by SLAC is to use a single multimoded waveguide to deliver the power of all the subpulses. This scheme requires a mode launcher that can deliver each subpulse by way of a different waveguide mode through selective phasing of the sources when combining their power. We present a compact design for such a mode launcher that converts the power from four rectangular waveguide feeds to separate modes in a multi-moded circular guide through coupling slots. Such a design has been simulated and found to satisfy the requirements for high efficiency and low surface fields.

  19. Electrically controlled optical-mode switch for fundamental mode and first order mode

    NASA Astrophysics Data System (ADS)

    Imansyah, Ryan; Tanaka, Tatsushi; Himbele, Luke; Jiang, Haisong; Hamamoto, Kiichi

    2016-08-01

    We have proposed an optical mode switch, the principle of which is based on the partial phase shift of injected light; therefore, one important issue is to clarify the proper design criteria for the mode combiner section. We focused on the bending radius of the S-bend waveguide issue that is connected to the multi mode waveguide in the Y-junction section that acts as mode combiner. Long radius leads to undesired mode coupling before the Y-junction section, whereas a short radius causes radiation loss. Thus, we simulated this mode combiner by the beam-propagation method to obtain the proper radius. In addition, we used a trench pin structure to simplify the fabrication process into a single-step dry-etching process. As a result, we successfully fabricated an optical-mode switch with the bending radius R = 610 µm. It showed the successful electrical mode switching and the achieved mode crosstalk was approximately ‑10 dB for 1550 nm wavelength with the injection current of 60 mA (5.7 V).

  20. Theory of psychological adaptive modes.

    PubMed

    Lehti, Juha

    2016-05-01

    When an individual is facing a stressor and normal stress-response mechanism cannot guarantee sufficient adaptation, special emotional states, adaptive modes, are activated (for example a depressive reaction). Adaptive modes are involuntary states of mind, they are of comprehensive nature, they interfere with normal functioning, and they cannot be repressed or controlled the same way as many emotions. Their transformational nature differentiates them from other emotional states. The object of the adaptive mode is to optimize the problem-solving abilities according to the situation that has provoked the mode. Cognitions and emotions during the adaptive mode are different than in a normal mental state. These altered cognitions and emotional reactions guide the individual to use the correct coping skills in order to deal with the stressor. Successful adaptation will cause the adaptive mode to fade off since the adaptive mode is no longer necessary, and the process as a whole will lead to raised well-being. However, if the adaptation process is inadequate, then the transformation period is prolonged, and the adaptive mode will turn into a dysfunctional state. Many psychiatric disorders are such maladaptive processes. The maladaptive processes can be turned into functional ones by using adaptive skills that are used in functional adaptive processes. PMID:27063089

  1. The double-mode Cepheids

    NASA Astrophysics Data System (ADS)

    Balona, L. A.

    1985-06-01

    Recent observational and theoretical results on double-mode Cepheids are reviewed. The likelihood that recently proposed candidate Cepheids are indeed Cepheids is evaluated. Periods, period ratios, and semi-amplitudes of the light and radial velocity variations of double-mode Cepheids are given. The physical and pulsational properties of double-mode Cepheids are discussed, reviewing evidence that these stars are Population I objects of high mass and that they all have the same mean effective temperature. The discovery of strong H-alpha emission occurring at seemingly random phases is addressed. Attempts to resolve the mass discrepancy problem of double-mode Cepheids, which results from observations showing that these Cepheids are indistinguishable from normal Cepheids of similar period, are reviewed along with attempts to find the cause of double-mode pulsation.

  2. Helicon modes in uniform plasmas. I. Low m modes

    NASA Astrophysics Data System (ADS)

    Urrutia, J. M.; Stenzel, R. L.

    2015-09-01

    Helicons are whistler modes with azimuthal wave numbers. They arise in bounded gaseous and solid state plasmas, but the present work shows that very similar modes also exist in unbounded uniform plasmas. The antenna properties determine the mode structure. A simple antenna is a magnetic loop with dipole moment aligned either along or across the ambient background magnetic field B0. For such configurations, the wave magnetic field has been measured in space and time in a large and uniform laboratory plasma. The observed wave topology for a dipole along B0 is similar to that of an m = 0 helicon mode. It consists of a sequence of alternating whistler vortices. For a dipole across B0, an m = 1 mode is excited which can be considered as a transverse vortex which rotates around B0. In m = 0 modes, the field lines are confined to each half-wavelength vortex while for m = 1 modes they pass through the entire wave train. A subset of m = 1 field lines forms two nested helices which rotate in space and time like corkscrews. Depending on the type of the antenna, both m = + 1 and m = -1 modes can be excited. Helicons in unbounded plasmas also propagate transverse to B0. The transverse and parallel wave numbers are about equal and form oblique phase fronts as in whistler Gendrin modes. By superimposing small amplitude fields of several loop antennas, various antenna combinations have been created. These include rotating field antennas, helical antennas, and directional antennas. The radiation efficiency is quantified by the radiation resistance. Since helicons exist in unbounded laboratory plasmas, they can also arise in space plasmas.

  3. Inter-comb synchronization by mode-to-mode locking

    NASA Astrophysics Data System (ADS)

    Chun, Byung Jae; Kim, Young-Jin; Kim, Seung-Woo

    2016-08-01

    Two combs of fiber femtosecond lasers are synchronized through the optical frequency reference created by injection-locking of a diode laser to a single comb mode. Maintaining a mHz-level narrow linewidth, the optical frequency reference permits two combs to be stabilized by mode-to-mode locking with a relative stability of 1.52  ×  10‑16 at 10 s with a frequency slip of 2.46 mHz. This inter-comb synchronization can be utilized for applications such as dual-comb spectroscopy or ultra-short pulse synthesis without extra narrow-linewidth lasers.

  4. Mode identification from spectroscopy of gravity-mode pulsators

    NASA Astrophysics Data System (ADS)

    Pollard, K. R.; Brunsden, E.; Cottrell, P. L.; Davie, M.; Greenwood, A.; Wright, D. J.; De Cat, P.

    2014-02-01

    The gravity modes present in γ Doradus stars probe the deep stellar interiors and are thus of particular interest in asteroseismology. For the MUSICIAN programme at the University of Canterbury, we obtain extensive high-resolution echelle spectra of γ Dor stars from the Mt John University Observatory in New Zealand. We analyze these to obtain the pulsational frequencies and identify these with the multiple pulsational modes excited in the star. A summary of recent results from our spectroscopic mode-identification programme is given.

  5. Current-interchange tearing modes: Conversion of interchange-type modes to tearing modes

    SciTech Connect

    Zheng, L. J.; Furukawa, M.

    2010-05-15

    It is shown that, in addition to usual neoclassical tearing modes, another type of nonclassical tearing mode exists in tokamaks: viz., current-interchange tearing modes (CITMs). CITMs are directly driven by unstable pressure-driven electromagnetic or electrostatic modes of the interchange type (e.g., interchange/ballooning modes, drift waves, etc.) due to the current gradient in tokamaks. Interchange-type modes exchange not only thermal and magnetic energies between flux tubes but also current. In a plasma with a current (or resistivity) gradient, such an interchange can create a current sheet at a mode resonance surface and result in the excitation of CITMs. Note that the interchange mode (i.e., Rayleigh-Taylor instability) is fundamental to tokamak physics. This new theory has an effect on both resistive magnetohydrodynamic stability and transport theories. Instabilities of the interchange type could be directly converted into CITMs, alternative to forming turbulent eddies through nonlinear coupling as in conventional transport theories. In particular, our CITM theory fills in the component in the transport theory of Rechester and Rosenbluth [Phys. Rev. Lett. 40, 38 (1978)] for the origin of magnetic island structure in axisymmetric tokamaks.

  6. Intracranial self-stimulation reward thresholds during morphine withdrawal in rats bred for high (HiS) and low (LoS) saccharin intake

    PubMed Central

    Holtz, Nathan A.; Radke, Anna K.; Zlebnik, Natalie E.; Harris, Andrew C.; Carroll, Marilyn E.

    2015-01-01

    Rational Sweet preference is a marker of vulnerability to substance use disorders, and rats selectively bred for high (HiS) vs. low saccharin (LoS) intake display potentiated drug-seeking behaviors. Recent work indicated that LoS rats were more responsive to the negative effects of drugs in several assays. Objective The current study used the intracranial self-stimulation (ICSS) procedure to investigate the anhedonic component of morphine withdrawal in male HiS and LoS rats. Methods Rats were administered morphine (10 mg/kg) or saline for 8 days. To evaluate withdrawal effects, reward thresholds were measured 24 and 28 h following the 8th morphine injection (spontaneous withdrawal) and again for 4 days following daily acute morphine and naloxone (1 mg/kg) administration (precipitated withdrawal). Results Twenty-four hr following the final morphine injection, reward thresholds in LoS rats were significantly elevated compared to reward thresholds in LoS controls, indicating spontaneous withdrawal. This effect was not observed in HiS rats. LoS rats also showed greater elevations of reward thresholds on several days during naloxone-precipitated withdrawal compared to their HiS counterparts. Conclusions LoS rats were more sensitive to morphine withdrawal-mediated elevations in ICSS thresholds than HiS rats. While these differences were generally modest, our data suggest that severity of the negative affective component of opiate withdrawal may be influenced by genotypes related to addiction vulnerability. PMID:25582876

  7. Physical view on migration modes

    PubMed Central

    Mierke, Claudia Tanja

    2015-01-01

    Cellular motility is essential for many processes such as embryonic development, wound healing processes, tissue assembly and regeneration, immune cell trafficing and diseases such as cancer. The migration efficiency and the migratory potential depend on the type of migration mode. The previously established migration modes such as epithelial (non-migratory) and mesenchymal (migratory) as well as amoeboid (squeezing motility) relay mainly on phenomenological criteria such as cell morphology and molecular biological criteria such as gene expression. However, the physical view on the migration modes is still not well understood. As the process of malignant cancer progression such as metastasis depends on the migration of single cancer cells and their migration mode, this review focuses on the different migration strategies and discusses which mechanical prerequisites are necessary to perform a special migration mode through a 3-dimensional microenvironment. In particular, this review discusses how cells can distinguish and finally switch between the migration modes and what impact do the physical properties of cells and their microenvironment have on the transition between the novel migration modes such as blebbing and protrusive motility. PMID:26192136

  8. Spatiotemporal mode structure of nonlinearly coupled drift wave modes

    SciTech Connect

    Brandt, Christian; Grulke, Olaf; Klinger, Thomas; Negrete, Jose Jr.; Bousselin, Guillaume; Brochard, Frederic; Bonhomme, Gerard; Oldenbuerger, Stella

    2011-11-15

    This paper presents full cross-section measurements of drift waves in the linear magnetized plasma of the Mirabelle device. Drift wave modes are studied in regimes of weakly developed turbulence. The drift wave modes develop azimuthal space-time structures of plasma density, plasma potential, and visible light fluctuations. A fast camera diagnostic is used to record visible light fluctuations of the plasma column in an azimuthal cross section with a temporal resolution of 10 {mu}s corresponding approximately to 10% of the typical drift wave period. Mode coupling and drift wave dispersion are studied by spatiotemporal Fourier decomposition of the camera frames. The observed coupling between modes is compared to calculations of nonlinearly coupled oscillators described by the Kuramoto model.

  9. Reduced emotional signs of opiate withdrawal in rats selectively bred for low (LoS) versus high (HiS) saccharin intake

    PubMed Central

    Radke, Anna K.; Holtz, Nathan A.; Gewirtz, Jonathan C.; Carroll, Marilyn E.

    2013-01-01

    Rationale Rats bred for high (HiS) and low (LoS) saccharin intake exhibit divergent behavioral responses to multiple drugs of abuse, with HiS rats displaying greater vulnerability to drug taking. Previous research indicates that this effect may be due to increased sensitivity to reward in HiS rats and to the aversive effects of acute drug administration in LoS rats. Objective The current study investigated whether HiS and LoS rats also exhibit different behavioral signs of withdrawal following one or repeated opiate exposures. Methods Emotional signs of opiate withdrawal were assessed with potentiation of the acoustic startle reflex and conditioned place aversion (CPA) in male and female HiS and LoS rats. Startle was measured before and 4 h after a 10 mg/kg injection of morphine on days 1, 2, and 7 of opiate exposure. CPA was induced with a two-day, naloxone-precipitated conditioning paradigm. Somatic signs of withdrawal and weight loss were used also measured. Results Male and female LoS rats exhibited lower startle potentiation than HiS rats on the seventh day of morphine exposure. LoS male rats also failed to develop a CPA to morphine withdrawal. No differences in physical withdrawal signs were observed between HiS and LoS rats, but males of both lines had more physical signs of withdrawal than females. Conclusions These results suggest that LoS rats are less vulnerable to the negative emotional effects of morphine withdrawal than HiS rats. A less severe withdrawal syndrome may contribute to decreased levels of drug taking in the LoS line. PMID:23254375

  10. Mode synthesizing atomic force microscopy and mode-synthesizing sensing

    DOEpatents

    Passian, Ali; Thundat, Thomas George; Tetard, Laurene

    2013-05-17

    A method of analyzing a sample that includes applying a first set of energies at a first set of frequencies to a sample and applying, simultaneously with the applying the first set of energies, a second set of energies at a second set of frequencies, wherein the first set of energies and the second set of energies form a multi-mode coupling. The method further includes detecting an effect of the multi-mode coupling.

  11. Identification and analysis of CYP7A1, CYP17A1, CYP20A1, CYP27A1 and CYP51A1 in cynomolgus macaques.

    PubMed

    Uno, Yasuhiro; Hosaka, Shinya; Yamazaki, Hiroshi

    2014-12-01

    Cytochromes P450 (P450) are important for not only drug metabolism and toxicity, but also biosynthesis and metabolism of cholesterol and bile acids, and steroid synthesis. In cynomolgus macaques, widely used in biomedical research, we have characterized P450 cDNAs, which were isolated as expressed sequence tags of cynomolgus macaque liver. In this study, cynomolgus CYP7A1, CYP17A1, CYP20A1, CYP27A1 and CYP51A1 cDNAs were characterized by sequence analysis, phylogenetic analysis and tissue expression pattern. By sequence analysis, these five cynomolgus P450s had high sequence identities (94-99%) to the human orthologs in amino acids. By phylogenetic analysis, each cynomolgus P450 was more closely related to the human ortholog as compared with the dog or rat ortholog. By quantitative polymerase chain reaction, among the 10 tissue types, CYP7A1 and CYP17A1 mRNAs were preferentially expressed in liver and adrenal gland, respectively. Cynomolgus CYP27A1 and CYP51A1 mRNAs were most abundantly expressed in liver and testis, respectively. Cynomolgus CYP20A1 mRNA was expressed in all the tissues, including brain and liver. Tissue expression patterns of each cynomolgus P450 were generally similar to that of the human ortholog. These results suggest the molecular similarities of CYP7A1, CYP17A1, CYP20A1, CYP27A1 and CYP51A1 between cynomolgus macaques and humans. PMID:25649950

  12. Interstellar Hydrogen Fluxes Measured by IBEX-Lo in 2009: Numerical Modeling and Comparison with the Data

    NASA Astrophysics Data System (ADS)

    Katushkina, O. A.; Izmodenov, V. V.; Alexashov, D. B.; Schwadron, N. A.; McComas, D. J.

    2015-10-01

    In this paper, we perform numerical modeling of the interstellar hydrogen fluxes measured by IBEX-Lo during orbit 23 (spring 2009) using a state-of-the-art kinetic model of the interstellar neutral hydrogen distribution in the heliosphere. This model takes into account the temporal and heliolatitudinal variations of the solar parameters as well as the non-Maxwellian kinetic properties of the hydrogen distribution due to charge exchange in the heliospheric interface. We found that there is a qualitative difference between the IBEX-Lo data and the modeling results obtained with the three-dimensional, time-dependent model. Namely, the model predicts a larger count rate in energy bin 2 (20-41 eV) than in energy bin 1 (11-21 eV), while the data shows the opposite case. We perform study of the model parameter effects on the IBEX-Lo fluxes and the ratio of fluxes in two energy channels. We show that the most important parameter, which has a major influence on the ratio of the fluxes in the two energy bins, is the solar radiation pressure. The parameter fitting procedure shows that the best agreement between the model result and the data occurs when the ratio of the solar radiation pressure to the solar gravitation, μ0, is {1.26}-0.076+0.06, and the total ionization rate of hydrogen at 1 AU is {β }E,0={3.7}-0.35+0.39× {10}-7 s-1. We have found that the value of μ0 is much larger than μ0 = 0.89, which is the value derived from the integrated solar Lyα flux data for the period of time studied. We discuss possible reasons for the differences.

  13. The origins of metamodality in visual object area LO: Bodily topographical biases and increased functional connectivity to S1

    PubMed Central

    Tal, Zohar; Geva, Ran; Amedi, Amir

    2016-01-01

    Recent evidence from blind participants suggests that visual areas are task-oriented and sensory modality input independent rather than sensory-specific to vision. Specifically, visual areas are thought to retain their functional selectivity when using non-visual inputs (touch or sound) even without having any visual experience. However, this theory is still controversial since it is not clear whether this also characterizes the sighted brain, and whether the reported results in the sighted reflect basic fundamental a-modal processes or are an epiphenomenon to a large extent. In the current study, we addressed these questions using a series of fMRI experiments aimed to explore visual cortex responses to passive touch on various body parts and the coupling between the parietal and visual cortices as manifested by functional connectivity. We show that passive touch robustly activated the object selective parts of the lateral–occipital (LO) cortex while deactivating almost all other occipital–retinotopic-areas. Furthermore, passive touch responses in the visual cortex were specific to hand and upper trunk stimulations. Psychophysiological interaction (PPI) analysis suggests that LO is functionally connected to the hand area in the primary somatosensory homunculus (S1), during hand and shoulder stimulations but not to any of the other body parts. We suggest that LO is a fundamental hub that serves as a node between visual-object selective areas and S1 hand representation, probably due to the critical evolutionary role of touch in object recognition and manipulation. These results might also point to a more general principle suggesting that recruitment or deactivation of the visual cortex by other sensory input depends on the ecological relevance of the information conveyed by this input to the task/computations carried out by each area or network. This is likely to rely on the unique and differential pattern of connectivity for each visual area with the rest of the

  14. The origins of metamodality in visual object area LO: Bodily topographical biases and increased functional connectivity to S1.

    PubMed

    Tal, Zohar; Geva, Ran; Amedi, Amir

    2016-02-15

    Recent evidence from blind participants suggests that visual areas are task-oriented and sensory modality input independent rather than sensory-specific to vision. Specifically, visual areas are thought to retain their functional selectivity when using non-visual inputs (touch or sound) even without having any visual experience. However, this theory is still controversial since it is not clear whether this also characterizes the sighted brain, and whether the reported results in the sighted reflect basic fundamental a-modal processes or are an epiphenomenon to a large extent. In the current study, we addressed these questions using a series of fMRI experiments aimed to explore visual cortex responses to passive touch on various body parts and the coupling between the parietal and visual cortices as manifested by functional connectivity. We show that passive touch robustly activated the object selective parts of the lateral-occipital (LO) cortex while deactivating almost all other occipital-retinotopic-areas. Furthermore, passive touch responses in the visual cortex were specific to hand and upper trunk stimulations. Psychophysiological interaction (PPI) analysis suggests that LO is functionally connected to the hand area in the primary somatosensory homunculus (S1), during hand and shoulder stimulations but not to any of the other body parts. We suggest that LO is a fundamental hub that serves as a node between visual-object selective areas and S1 hand representation, probably due to the critical evolutionary role of touch in object recognition and manipulation. These results might also point to a more general principle suggesting that recruitment or deactivation of the visual cortex by other sensory input depends on the ecological relevance of the information conveyed by this input to the task/computations carried out by each area or network. This is likely to rely on the unique and differential pattern of connectivity for each visual area with the rest of the

  15. Three-dimensional ray tracing of electrostatic cyclotron harmonic waves and Z mode electromagnetic waves in the magnetosphere

    NASA Astrophysics Data System (ADS)

    Hashimoto, K.; Yamaashi, K.; Kimura, I.

    1987-08-01

    Three-dimensional ray tracing is performed for electrostatic electron cyclotron harmonic waves and Z mode electromagnetic waves in the earth's magnetosphere using the hot dispersion relation. Propagation characteristics of cyclotron harmonic waves under the electrostatic approximation are considered, and it is noted that waves starting near the equator can propagate over a long distance without damping. Ray tracing without the electrostatic approximation confirms mode conversion from cyclotron harmonic waves to Z mode electromagnetic waves, and the conditions for the conversion are clarified. It is suggested that further conversion to the L-O mode continuum radiation is possible under strict constraints. The present results are not inconsistent with the conversion mechanism for the generation of escaping continuum radiation in the magnetosphere.

  16. Advantages of Karhunen Loève transform over fast Fourier transform for planetary radar and space debris detection

    NASA Astrophysics Data System (ADS)

    Maccone, Claudio

    2007-04-01

    The present article describes that the range of any radiotelescope (and radar in general) may be increased by virtue of software, if one replaces the fast Fourier transform by the Karhunen Loève transform. The range increases with the inverse of the fourth root of the signal-to-noise ratio when this ratio decreases. Thus, the range on any radiotelescope (and radar) may be increased without changing the hardware at all, but by changing the software only. This improvement in the range of the radiotelescope is currently implemented at the 32-m antenna located at Medicina, near Bologna, in Italy, for both SETI and general radioastronomy.

  17. Seasonality and paleoecology of the late Cretaceous multi-taxa vertebrate assemblage of "Lo Hueco" (central eastern Spain).

    PubMed

    Domingo, Laura; Barroso-Barcenilla, Fernando; Cambra-Moo, Oscar

    2015-01-01

    Isotopic studies of multi-taxa terrestrial vertebrate assemblages allow determination of paleoclimatic and paleoecological aspects on account of the different information supplied by each taxon. The late Campanian-early Maastrichtian "Lo Hueco" Fossil-Lagerstätte (central eastern Spain), located at a subtropical paleolatitude of ~31°N, constitutes an ideal setting to carry out this task due to its abundant and diverse vertebrate assemblage. Local δ18OPO4 values estimated from δ18OPO4 values of theropods, sauropods, crocodyliforms, and turtles are close to δ18OH2O values observed at modern subtropical latitudes. Theropod δ18OH2O values are lower than those shown by crocodyliforms and turtles, indicating that terrestrial endothermic taxa record δ18OH2O values throughout the year, whereas semiaquatic ectothermic taxa δ18OH2O values represent local meteoric waters over a shorter time period when conditions are favorable for bioapatite synthesis (warm season). Temperatures calculated by combining theropod, crocodyliform, and turtle δ18OH2O values and gar δ18OPO4 have enabled us to estimate seasonal variability as the difference between mean annual temperature (MAT, yielded by theropods) and temperature of the warmest months (TWMs, provided by crocodyliforms and turtles). ΔTWMs-MAT value does not point to a significantly different seasonal thermal variability when compared to modern coastal subtropical meteorological stations and Late Cretaceous rudists from eastern Tethys. Bioapatite and bulk organic matter δ13C values point to a C3 environment in the "Lo Hueco" area. The estimated fractionation between sauropod enamel and diet is ~15‰. While waiting for paleoecological information yielded by the ongoing morphological study of the "Lo Hueco" crocodyliforms, δ13C and δ18OCO3 results point to incorporation of food items with brackish influence, but preferential ingestion of freshwater. "Lo Hueco" turtles showed the lowest δ13C and δ18OCO3 values of the

  18. Seasonality and Paleoecology of the Late Cretaceous Multi-Taxa Vertebrate Assemblage of “Lo Hueco” (Central Eastern Spain)

    PubMed Central

    Domingo, Laura; Barroso-Barcenilla, Fernando; Cambra-Moo, Oscar

    2015-01-01

    Isotopic studies of multi-taxa terrestrial vertebrate assemblages allow determination of paleoclimatic and paleoecological aspects on account of the different information supplied by each taxon. The late Campanian-early Maastrichtian “Lo Hueco” Fossil-Lagerstätte (central eastern Spain), located at a subtropical paleolatitude of ~31°N, constitutes an ideal setting to carry out this task due to its abundant and diverse vertebrate assemblage. Local δ18OPO4 values estimated from δ18OPO4 values of theropods, sauropods, crocodyliforms, and turtles are close to δ18OH2O values observed at modern subtropical latitudes. Theropod δ18OH2O values are lower than those shown by crocodyliforms and turtles, indicating that terrestrial endothermic taxa record δ18OH2O values throughout the year, whereas semiaquatic ectothermic taxa δ18OH2O values represent local meteoric waters over a shorter time period when conditions are favorable for bioapatite synthesis (warm season). Temperatures calculated by combining theropod, crocodyliform, and turtle δ18OH2O values and gar δ18OPO4 have enabled us to estimate seasonal variability as the difference between mean annual temperature (MAT, yielded by theropods) and temperature of the warmest months (TWMs, provided by crocodyliforms and turtles). ΔTWMs-MAT value does not point to a significantly different seasonal thermal variability when compared to modern coastal subtropical meteorological stations and Late Cretaceous rudists from eastern Tethys. Bioapatite and bulk organic matter δ13C values point to a C3 environment in the “Lo Hueco” area. The estimated fractionation between sauropod enamel and diet is ~15‰. While waiting for paleoecological information yielded by the ongoing morphological study of the “Lo Hueco” crocodyliforms, δ13C and δ18OCO3 results point to incorporation of food items with brackish influence, but preferential ingestion of freshwater. “Lo Hueco” turtles showed the lowest δ13C and δ18OCO3

  19. Optical and X-ray studies of chromospherically active stars: FR Cancri, HD 95559 and LO Pegasi

    NASA Technical Reports Server (NTRS)

    Pandey, J. C.; Singh, K. P.; Drake, S. A.; Sagar, R.

    2005-01-01

    We present a multiwavelength study of three chromospherically active stars, namely FR Cnc (= BD +16 degrees 1753), HD 95559 and LO Peg (=BD +22 degrees 4409), including newly obtained optical photometry, (for FR Cnc) low-resolution optical spectroscopy, as well as archival IR and X-ray observations. The BVR photometry carried out during the years 2001 - 2004 has found significant photometric variability to be present in all three stars. For FR Cnc, a photometric period 0.826685 +/- 0.000034 d has been established. The strong variation in the phase and amplitude of the FR Cnc light curves when folded on this period implies the presence of evolving and migrating spots or spot groups on its surface. Two independent spots with migration periods of 0.97 and 0.93 years respectively are inferred. The photometry of HD 95559 suggests the formation of a spot (group) during the interval of our observations. We infer the existence of two independent spots or groups in the photosphere of LO Peg, one of which has a migration period of 1.12 years. The optical spectroscopy of FR Cnc carried out during 2002-2003, reveals the presence of strong and variable Ca I1 H and K, H(sub beta) and H(sub alpha) emission features indicative of high level of chromospheric activity. The value of 5.3 for the ratio of the excess emission in H(sub alpha) to H(sub beta), EH(sub alpha)/EH(sub beta), suggests that the chromospheric emission may arise from an extended off-limb region. We have searched for the presence of color excesses in the near-IR JHK bands of these stars using 2MASS data, but none of them appear to have any significant color excess. We have also analyzed archival X-ray observations of HD 95559 and LO Peg carried out by with the ROSAT observatory. The best fit models to their X-ray spectra imply the presence of two coronal plasma components of differing temperatures and with sub-solar metal abundances. The inferred emission measures and temperatures of these systems are similar to

  20. Investigation of lightweight designs and materials for LO2 and LH2 propellant tanks for space vehicles, phase 1

    NASA Technical Reports Server (NTRS)

    1975-01-01

    Design, analysis, and fabrication studies were performed on nonintegral (suspended) tanks using a representative space tug design. The LH2 and LO2 tank concept selection was developed. Tank geometries and support relationships were investigated using tug design propellant inertias and ullage pressures, then compared based on total tug systems effects. The tank combinations which resulted in the maximum payload were selected. Tests were conducted on samples of membrane material which was processed in a manner simulating production tank fabrication operations to determine fabrication effects on the fracture toughness of the tank material. Fracture mechanics analyses were also performed to establish a preliminary set of allowables for initial defects.

  1. Optical and X-Ray Studies of Chromospherically Active Stars: FR Cancri, HD 95559, and LO Pegasi

    NASA Astrophysics Data System (ADS)

    Pandey, J. C.; Singh, K. P.; Drake, S. A.; Sagar, R.

    2005-09-01

    We present a multiwavelength study of three chromospherically active stars, namely, FR Cnc (BD +16°1753), HD 95559, and LO Peg (BD +22°4409), including newly obtained optical photometry and low-resolution optical spectroscopy for FR Cnc, as well as archival IR and X-ray observations. The BVR photometry carried out from 2001 to 2004 has found significant photometric variability to be present in all three stars. For FR Cnc, a photometric period of 0.8267+/-0.0004 days has been established. The strong variation in the phase and amplitude of the FR Cnc light curves when folded on this period implies the presence of evolving and migrating spots or spot groups on its surface. Two independent spots with migration periods of 0.97 and 0.93 yr, respectively, are inferred. The photometry of HD 95559 suggests the formation of a spot (group) during the interval of our observations. We infer the existence of two independent spots or groups in the photosphere of LO Peg, one of which has a migration period of 1.12 yr. The optical spectroscopy of FR Cnc carried out during 2002-2003 reveals the presence of strong and variable Ca II H and K, Hβ, and Hα emission features indicative of a high level of chromospheric activity. The value of 5.3 for the ratio of the excess emission in Hα to Hβ, EHα/EHβ, suggests that the chromospheric emission may arise from an extended off-limb region. We have searched for the presence of color excesses in the near-IR JHK bands of these stars using Two Micron All Sky Survey data, but none of them appear to have any significant color excess. We have also analyzed archival X-ray observations of HD 95559 and LO Peg carried out with the ROSAT observatory. The best-fit models to their X-ray spectra imply the presence of two coronal plasma components of differing temperatures and with subsolar metal abundances. The inferred emission measures and temperatures of these systems are similar to those found for other active dwarf stars. The kinematics of FR

  2. Multi-mode radio frequency device

    DOEpatents

    Gilbert, Ronald W.; Carrender, Curtis Lee; Anderson, Gordon A.; Steele, Kerry D.

    2007-02-13

    A transponder device having multiple modes of operation, such as an active mode and a passive mode, wherein the modes of operation are selected in response to the strength of a received radio frequency signal. A communication system is also provided having a transceiver configured to transmit a radio frequency signal and to receive a responsive signal, and a transponder configured to operate in a plurality of modes and to activate modes of operation in response to the radio frequency signal. Ideally, each mode of operation is activated and deactivated independent of the other modes, although two or more modes may be concurrently operational.

  3. Single mode levitation and translation

    NASA Technical Reports Server (NTRS)

    Barmatz, Martin B. (Inventor); Allen, James L. (Inventor)

    1988-01-01

    A single frequency resonance mode is applied by a transducer to acoustically levitate an object within a chamber. This process allows smooth movement of the object and suppression of unwanted levitation modes that would urge the object to a different levitation position. A plunger forms one end of the chamber, and the frequency changes as the plunger moves. Acoustic energy is applied to opposite sides of the chamber, with the acoustic energy on opposite sides being substantially 180 degrees out of phase.

  4. Nonlinear mode decomposition: A noise-robust, adaptive decomposition method

    NASA Astrophysics Data System (ADS)

    Iatsenko, Dmytro; McClintock, Peter V. E.; Stefanovska, Aneta

    2015-09-01

    The signals emanating from complex systems are usually composed of a mixture of different oscillations which, for a reliable analysis, should be separated from each other and from the inevitable background of noise. Here we introduce an adaptive decomposition tool—nonlinear mode decomposition (NMD)—which decomposes a given signal into a set of physically meaningful oscillations for any wave form, simultaneously removing the noise. NMD is based on the powerful combination of time-frequency analysis techniques—which, together with the adaptive choice of their parameters, make it extremely noise robust—and surrogate data tests used to identify interdependent oscillations and to distinguish deterministic from random activity. We illustrate the application of NMD to both simulated and real signals and demonstrate its qualitative and quantitative superiority over other approaches, such as (ensemble) empirical mode decomposition, Karhunen-Loève expansion, and independent component analysis. We point out that NMD is likely to be applicable and useful in many different areas of research, such as geophysics, finance, and the life sciences. The necessary matlab codes for running NMD are freely available for download.

  5. Nonlinear mode decomposition: a noise-robust, adaptive decomposition method.

    PubMed

    Iatsenko, Dmytro; McClintock, Peter V E; Stefanovska, Aneta

    2015-09-01

    The signals emanating from complex systems are usually composed of a mixture of different oscillations which, for a reliable analysis, should be separated from each other and from the inevitable background of noise. Here we introduce an adaptive decomposition tool-nonlinear mode decomposition (NMD)-which decomposes a given signal into a set of physically meaningful oscillations for any wave form, simultaneously removing the noise. NMD is based on the powerful combination of time-frequency analysis techniques-which, together with the adaptive choice of their parameters, make it extremely noise robust-and surrogate data tests used to identify interdependent oscillations and to distinguish deterministic from random activity. We illustrate the application of NMD to both simulated and real signals and demonstrate its qualitative and quantitative superiority over other approaches, such as (ensemble) empirical mode decomposition, Karhunen-Loève expansion, and independent component analysis. We point out that NMD is likely to be applicable and useful in many different areas of research, such as geophysics, finance, and the life sciences. The necessary matlab codes for running NMD are freely available for download. PMID:26465549

  6. Adaptive mode control of a few-mode fiber by real-time mode decomposition.

    PubMed

    Huang, Liangjin; Leng, Jinyong; Zhou, Pu; Guo, Shaofeng; Lü, Haibin; Cheng, Xiang'ai

    2015-10-19

    A novel approach to adaptively control the beam profile in a few-mode fiber is experimentally demonstrated. We stress the fiber through an electric-controlled polarization controller, whose driven voltage depends on the current and target modal content difference obtained with the real-time mode decomposition. We have achieved selective excitations of LP01 and LP11 modes, as well as significant improvement of the beam quality factor, which may play crucial roles for high-power fiber lasers, fiber based telecommunication systems and other fundamental researches and applications. PMID:26480466

  7. Jet-vetoed Higgs cross section in gluon fusion at N3LO+NNLL with small-R resummation

    NASA Astrophysics Data System (ADS)

    Banfi, Andrea; Caola, Fabrizio; Dreyer, Frédéric A.; Monni, Pier Francesco; Salam, Gavin P.; Zanderighi, Giulia; Dulat, Falko

    2016-04-01

    We present new results for the jet-veto efficiency and zero-jet cross section in Higgs production through gluon fusion. We incorporate the N3LO corrections to the total cross section, the NNLO corrections to the 1-jet rate, NNLL resummation for the jet p t and LL resummation for the jet radius dependence. Our results include known finite-mass corrections and are obtained using the jet-veto efficiency method, updated relative to earlier work to take into account what has been learnt from the new precision calculations that we include. For 13 TeV collisions and using our default choice for the renormalisation and factorisation scales, μ 0 = m H /2, the matched prediction for the jet-veto efficiency increases the pure N3LO prediction by about 2% and the two have comparable uncertainties. Relative to NNLO+NNLL results, the new prediction is 2% smaller and the uncertainty reduces from about 10% to a few percent. Results are also presented for the central scale μ 0 = m H .

  8. Metformin suppressed the proliferation of LoVo cells and induced a time-dependent metabolic and transcriptional alteration.

    PubMed

    He, Jiaojiao; Wang, Ke; Zheng, Ningning; Qiu, Yunping; Xie, Guoxiang; Su, Mingming; Jia, Wei; Li, Houkai

    2015-01-01

    Metformin is a widely used anti-diabetic drug with potential anti-tumor activity. However, little is known about its global metabolic and transcriptional impacts on tumor cells. In current study, we performed a metabolic profiling on human-derived colon cancer LoVo cells treated by 10 mM metformin for 8, 24 and 48 h. An obvious time-dependent metabolic alteration was observed from 8 to 48 h, prior to the reduction of cell viability. A total of 47, 45 and 66 differential metabolites were identified between control and metformin-treated cells at three time points. Most of the metabolites were up-regulated at 8 h, but down-regulated at 24 and 48 h by metformin. These metabolites were mainly involved in carbohydrates, lipids, amino acids, vitamins and nucleotides metabolism pathways. Meanwhile, the transcirptomic profile revealed 134 and 3061 differentially expressed genes at 8 and 24 h by metformin. In addition to the cancer signaling pathways, expression of genes involved in cell energy metabolism pathways was significantly altered, which were further validated with genes in glucose metabolism pathway. Altogether, our current data indicate that metformin suppressed the proliferation of LoVo cells, which may be due to the modulation on cell energy metabolism at both metabolic and transcriptional levels in a time-dependent way. PMID:26616174

  9. Metformin suppressed the proliferation of LoVo cells and induced a time-dependent metabolic and transcriptional alteration

    PubMed Central

    He, Jiaojiao; Wang, Ke; Zheng, Ningning; Qiu, Yunping; Xie, Guoxiang; Su, Mingming; Jia, Wei; Li, Houkai

    2015-01-01

    Metformin is a widely used anti-diabetic drug with potential anti-tumor activity. However, little is known about its global metabolic and transcriptional impacts on tumor cells. In current study, we performed a metabolic profiling on human-derived colon cancer LoVo cells treated by 10 mM metformin for 8, 24 and 48 h. An obvious time-dependent metabolic alteration was observed from 8 to 48 h, prior to the reduction of cell viability. A total of 47, 45 and 66 differential metabolites were identified between control and metformin-treated cells at three time points. Most of the metabolites were up-regulated at 8 h, but down-regulated at 24 and 48 h by metformin. These metabolites were mainly involved in carbohydrates, lipids, amino acids, vitamins and nucleotides metabolism pathways. Meanwhile, the transcirptomic profile revealed 134 and 3061 differentially expressed genes at 8 and 24 h by metformin. In addition to the cancer signaling pathways, expression of genes involved in cell energy metabolism pathways was significantly altered, which were further validated with genes in glucose metabolism pathway. Altogether, our current data indicate that metformin suppressed the proliferation of LoVo cells, which may be due to the modulation on cell energy metabolism at both metabolic and transcriptional levels in a time-dependent way. PMID:26616174

  10. Navier-Stokes computations with finite-rate chemistry for LO2/LH2 rocket engine plume flow studies

    NASA Technical Reports Server (NTRS)

    Dougherty, N. Sam; Liu, Baw-Lin

    1991-01-01

    Computational fluid dynamics methods have been developed and applied to Space Shuttle Main Engine LO2/LH2 plume flow simulation/analysis of airloading and convective base heating effects on the vehicle at high flight velocities and altitudes. New methods are described which were applied to the simulation of a Return-to-Launch-Site abort where the vehicle would fly briefly at negative angles of attack into its own plume. A simplified two-perfect-gases-mixing approach is used where one gas is the plume and the other is air at 180-deg and 135-deg flight angle of attack. Related research has resulted in real gas multiple-plume interaction methods with finite-rate chemistry described herein which are applied to the same high-altitude-flight conditions of 0 deg angle of attack. Continuing research plans are to study Orbiter wake/plume flows at several Mach numbers and altitudes during ascent and then to merge this model with the Shuttle 'nose-to-tail' aerodynamic and SRB plume models for an overall 'nose-to-plume' capability. These new methods are also applicable to future launch vehicles using clustered-engine LO2/LH2 propulsion.

  11. Inhibition of migration and induction of apoptosis in LoVo human colon cancer cells by polysaccharides from Ganoderma lucidum.

    PubMed

    Liang, Zeng-Enni; Yi, You-Jin; Guo, Yu-Tong; Wang, Ren-Cai; Hu, Qiu-Long; Xiong, Xing-Yao

    2015-11-01

    Ganoderma lucidum polysaccharides (GLPs), which were purified from the medicinal herb G. lucidum followed by ethanol precipitation, protein depletion using the Sevage assay, purification using DEAE‑cellulose (DE-52), dialysis and the use of ultrafiltration membranes, are used as an ingredient in traditional anticancer treatments in China. The aim of the current study was to evaluate the anticancer effects and investigate the underlying molecular mechanisms of GLPs on LoVo human colon cancer cells. The results demonstrated that the GLP‑mediated anticancer effect in LoVo cells was characterized by cytotoxicity, migration inhibition, enhanced DNA fragmentation, morphological alterations and increased lactate dehydrogenase release. Furthermore, the activation of caspases‑3, ‑8 and ‑9 was involved in GLP‑stimulated apoptosis. Additionally, treatment with GLPs promoted the expression of Fas and caspase‑3 proteins, whilst reducing the expression of cleaved poly(ADP‑ribose) polymerase. These data indicate that GLPs demonstrate potential antitumor activity in human colon cancer cells, predominantly through the inhibition of migration and induction of apoptosis. Furthermore, activation of the Fas/caspase-dependent apoptosis pathway is involved in the cytotoxicity of GLPs. PMID:26397202

  12. Titanosaur Osteoderms from the Upper Cretaceous of Lo Hueco (Spain) and Their Implications on the Armor of Laurasian Titanosaurs

    PubMed Central

    Vidal, Daniel; Ortega, Francisco; Sanz, José Luis

    2014-01-01

    Titanosaurs are the only sauropod dinosaurs known to bear a dermal armor. Their osteoderms are relatively rare finds, with few more than a hundred specimens recovered worldwide. Also, little is known about their intra-individual, intra-specific or inter-specific variability. The macrovertebrate site of Lo Hueco (Upper Cretaceous; Cuenca, Spain) has yielded several complete specimens of osteoderms, some associated with fairly articulated specimens. They are all variations of the morphotype known as bulb and root. The presence of only this morphotype in Europe, which is considered as the primitive condition among titanosaurs, seems to indicate that the known Upper Cretaceous Laurasian titanosaurs only bore these referred bulb and root osteoderms. An eliptic Fourier analysis on the outline of complete specimens from this morphotype reveals: i) that they truly are part of a morphological cline; and ii) the existence of a consistent correlation between the outline and the morphology of the bulb. Such variation along a cline is more consistent with intra-individual rather than inter-specific variation. The osteoderms associated with a single titanosaur individual from Lo Hueco reinforce this hypothesis. PMID:25118985

  13. Listeria monocytogenes LO28: Surface Physicochemical Properties and Ability To Form Biofilms at Different Temperatures and Growth Phases

    PubMed Central

    Chavant, Patrick; Martinie, Brigitte; Meylheuc, Thierry; Bellon-Fontaine, Marie-Noëlle; Hebraud, Michel

    2002-01-01

    The surface physicochemical properties of Listeria monocytogenes LO28 under different conditions (temperature and growth phase) were determined by use of microelectrophoresis and microbial adhesion to solvents. The effect of these parameters on adhesion and biofilm formation by L. monocytogenes LO28 on hydrophilic (stainless steel) and hydrophobic (polytetrafluoroethylene [PTFE]) surfaces was assessed. The bacterial cells were always negatively charged and possessed hydrophilic surface properties, which were negatively correlated with growth temperature. The colonization of the two surfaces, monitored by scanning electron microscopy, epifluorescence microscopy, and cell enumeration, showed that the strain had a great capacity to colonize both surfaces whatever the incubation temperature. However, biofilm formation was faster on the hydrophilic substratum. After 5 days at 37 or 20°C, the biofilm structure was composed of aggregates with a three-dimensional shape, but significant detachment took place on PTFE at 37°C. At 8°C, only a bacterial monolayer was visible on stainless steel, while no growth was observed on PTFE. The growth phase of bacteria used to inoculate surfaces had a significant effect only in some cases during the first steps of biofilm formation. The surface physicochemical properties of the strain are correlated with adhesion and surface colonization. PMID:11823213

  14. English vowel production by native Mandarin speakers: Influences of AoA, LoR, education, perception, and orthography

    NASA Astrophysics Data System (ADS)

    Bell-Berti, Fredericka; Yu, Yan Helen

    2005-09-01

    This study investigates relations among several factors that are expected to influence vowel production in second language learning, including AoA, LoR, L2 and general education, L2 perception, and orthography. Vowel production will be examined through duration and formant frequency measurements and listener identification. The results will be analyzed in relation to educational background and language use. Among the educational factors examined are general education level, English education (in their native land and/or New York City), and sound-annotating system experiences in Mandarin (Pinyin or Zhuyin). The language-use factors include AoA, LoR, language spoken at work and at home, and perception of English vowels. The hypotheses addressed include: (1) educational background, language use, and sound-annotating system experiences in Mandarin all influence L2 English speakers perception and production of English vowels; (2) the more accurately an L2 listener discriminates a vowel contrast, the more distinctly he/she produces that contrast.

  15. Single-mode squeezing in arbitrary spatial modes.

    PubMed

    Semmler, Marion; Berg-Johansen, Stefan; Chille, Vanessa; Gabriel, Christian; Banzer, Peter; Aiello, Andrea; Marquardt, Christoph; Leuchs, Gerd

    2016-04-01

    As the generation of squeezed states of light has become a standard technique in laboratories, attention is increasingly directed towards adapting the optical parameters of squeezed beams to the specific requirements of individual applications. It is known that imaging, metrology, and quantum information may benefit from using squeezed light with a tailored transverse spatial mode. However, experiments have so far been limited to generating only a few squeezed spatial modes within a given setup. Here, we present the generation of single-mode squeezing in Laguerre-Gauss and Bessel-Gauss modes, as well as an arbitrary intensity pattern, all from a single setup using a spatial light modulator (SLM). The degree of squeezing obtained is limited mainly by the initial squeezing and diffractive losses introduced by the SLM, while no excess noise from the SLM is detectable at the measured sideband. The experiment illustrates the single-mode concept in quantum optics and demonstrates the viability of current SLMs as flexible tools for the spatial reshaping of squeezed light. PMID:27137050

  16. Statistical light-mode dynamics of multipulse passive mode locking.

    PubMed

    Weill, Rafi; Well, Rafi; Vodonos, Boris; Gordon, Ariel; Gat, Omri; Fischer, Baruch

    2007-09-01

    We study the multipulse formation in passive mode locking in the framework of the statistical light-mode dynamics theory. It is a many-body theory that treats the complex many-mode laser system by statistical mechanics. We give a detailed theory and experimental verification for the important case of multiple-pulse formation in the laser cavity. We follow and extend our former work on the subject. We give a detailed analysis with a rigorous calculation of the partition function, the free energy, and the order parameter in the coarse-graining method within the mean-field theory that is exact in the light-mode system. The outcome is a comprehensive picture of multipulse formation and annihilation, pulse after pulse, in an almost quantized manner, as the noise ("temperature") or the light power is varied. We obtain the phase diagram of the system, showing a series of first-order phase transitions, each belonging to a different number of pulses. We also study the hysteresis behavior, typical for such thermodynamic systems. We elaborate on the role of the saturable absorber structure in determining the multipulse formation. The theoretical results are compared to experimental measurements that we obtained with mode-locked fiber lasers, and we find an excellent agreement. PMID:17930204

  17. Investigation of lightweight designs and materials for LO2 and LH2 propellant tanks for space vehicles, phase 2 and phase 3

    NASA Technical Reports Server (NTRS)

    1976-01-01

    Full size Tug LO2 and LH2 tank configurations were defined, based on selected tank geometries. These configurations were then locally modeled for computer stress analysis. A large subscale test tank, representing the selected Tug LO2 tank, was designed and analyzed. This tank was fabricated using procedures which represented production operations. An evaluation test program was outlined and a test procedure defined. The necessary test hardware was also fabricated.

  18. Overexpression of molecular chaperons GRP78 and GRP94 in CD44hi/CD24lo breast cancer stem cells

    PubMed Central

    Nami, Babak; Ghasemi-Dizgah, Armin; Vaseghi, Akbar

    2016-01-01

    Introduction: Breast cancer stem cell with CD44hi/CD24lo phonotype is described having stem cell properties and represented as the main driving factor in breast cancer initiation, growth, metastasis and low response to anti-cancer agents. Glucoseregulated proteins (GRPs) are heat shock protein family chaperons that are charged with regulation of protein machinery and modulation of endoplasmic reticulum homeostasis whose important roles in stem cell development and invasion of various cancers have been demonstrated. Here, we investigated the expression levels of GRP78 and GRP94 in CD44hi/CD24lo phenotype breast cancer stem cells (BCSCs). Methods: MCF7, T-47D and MDA-MB-231 breast cancer cell lines were used. CD44hi/CD24lo phenotype cell population were analyzed and sorted by fluorescence-activated cell sorting (FACS). Transcriptional and translational expression of GRP78 and GRP94 were investigated by western blotting and quantitative real time PCR. Results: Results showed different proportion of CD44hi/CD24lo phenotype cell population in their original bulk cells. The ranking of the cell lines in terms of CD44hi/CD24lo phenotype cell population was as MCF7lo phenotype cells exhibited higher mRNA and protein expression level of GRP78 and GRP94 compared to their original bulk cells. Conclusion: Our results show a relationship between overexpression of GRP78 and GRP94 and exhibiting CD44hi/CD24lo phenotype in breast cancer cells. We conclude that upregulation of GRPs may be an important factor in the emergence of CD44hi/CD24lo phenotype BCSCs features. PMID:27525228

  19. A Passive Thermal Carrier (LoTEC(c )) for Temperature Sensitive Materials Being Moved to and From ISS and for Shuttle (STS) Flights

    NASA Astrophysics Data System (ADS)

    Wessling, F. C.; Blackwood, J. M.; Holt, H. R.

    2002-01-01

    the use of power for transporting temperature sensitive materials to and from the International Space Station. LoTEC uses a combination of high thermal resistance insulation, careful thermal design and phase change materials to maintain temperature. It has been tested with phase change materials for three different interior temperatures (-16C, 0C, +4C). These temperatures are usable for preservation of many biological materials during transport. The exterior dimensions of LoTEC are approximately 250.7 x 436.9 x 514.1 mm. Thus, LoTEC fits into a standard mid-deck locker, an Express Rack, a SpaceHab rack or a rack in the Multi-Purpose Logistics Module (MPLM). LoTEC has an empty mass of approximately 9.6 kg and an internal volume of 22 Liters. This volume is reduced by the amount and type of phase change material (PCM) used. For example, eight kg of water ice and its containers would take up approximately half of the internal volume, leaving 11 Liters of space for the payload. Several different configurations have been considered to accommodate different payload dimensions.The interior dimensions of LoTEC are approximately 406 x 343 x 158 mm. Measured energy gain by LoTEC is approximately 0.14 watts per degrees Celsius. Performance data in the form of temperature versus time curves are included. Eight kg of PCM gives approximately eight days of constant temperature at typical STS interior temperatures. The temperature distribution in LoTEC is dependent on the PCM containers, the PCM used, and the location of the containers in LoTEC. Small, stand-alone data loggers record the temperatures. Refreezing of phase change materials depends on the facilities on board the ISS or the STS. Various methods of refreezing of phase change materials on the ISS are discussed.

  20. CERES Spatial Extent and Scan Modes

    Atmospheric Science Data Center

    2013-04-03

    ... CERES Examples: Spatial Extent and Scan Modes The first three images shown below show the areal coverage for ... the areal coverage and characteristics of particular CERES scan modes performed by the CERES instruments. The Cross-Track mode, a Fixed ...

  1. The effective degeneracy of protein normal modes

    NASA Astrophysics Data System (ADS)

    Na, Hyuntae; Song, Guang

    2016-06-01

    Normal modes are frequently computed and used to portray protein dynamics and interpret protein conformational changes. In this work, we investigate the nature of normal modes and find that the normal modes of proteins, especially those at the low frequency range (0–600 cm‑1), are highly susceptible to degeneracy. Two or more modes are degenerate if they have the same frequency and consequently any orthogonal transformation of them also is a valid representation of the mode subspace. Thus, degenerate modes can no longer characterize unique directions of motions as regular modes do. Though the normal modes of proteins are usually of different frequencies, the difference in frequency between neighboring modes is so small that, under even slight structural uncertainty that unavoidably exists in structure determination, it can easily vanish and as a result, a mode becomes effectively degenerate with its neighboring modes. This can be easily observed in that some modes seem to disappear and their matching modes cannot be found when the structure used to compute the modes is modified only slightly. We term this degeneracy the effective degeneracy of normal modes. This work is built upon our recent discovery that the vibrational spectrum of globular proteins is universal. The high density of modes observed in the vibrational frequency spectra of proteins renders their normal modes highly susceptible to degeneracy, under even the smallest structural uncertainty. Indeed, we find the degree of degeneracy of modes is proportional to the density of modes in the vibrational spectrum. This means that for modes at the same frequency, degeneracy is more severe for larger proteins. Degeneracy exists also in the modes of coarse-grained models, but to a much lesser extent than those of all-atom models. In closing, we discuss the implications of the effective degeneracy of normal modes: how it may significantly affect the ways in which normal modes are used in various normal modes

  2. The effective degeneracy of protein normal modes.

    PubMed

    Na, Hyuntae; Song, Guang

    2016-01-01

    Normal modes are frequently computed and used to portray protein dynamics and interpret protein conformational changes. In this work, we investigate the nature of normal modes and find that the normal modes of proteins, especially those at the low frequency range (0-600 cm(-1)), are highly susceptible to degeneracy. Two or more modes are degenerate if they have the same frequency and consequently any orthogonal transformation of them also is a valid representation of the mode subspace. Thus, degenerate modes can no longer characterize unique directions of motions as regular modes do. Though the normal modes of proteins are usually of different frequencies, the difference in frequency between neighboring modes is so small that, under even slight structural uncertainty that unavoidably exists in structure determination, it can easily vanish and as a result, a mode becomes effectively degenerate with its neighboring modes. This can be easily observed in that some modes seem to disappear and their matching modes cannot be found when the structure used to compute the modes is modified only slightly. We term this degeneracy the effective degeneracy of normal modes. This work is built upon our recent discovery that the vibrational spectrum of globular proteins is universal. The high density of modes observed in the vibrational frequency spectra of proteins renders their normal modes highly susceptible to degeneracy, under even the smallest structural uncertainty. Indeed, we find the degree of degeneracy of modes is proportional to the density of modes in the vibrational spectrum. This means that for modes at the same frequency, degeneracy is more severe for larger proteins. Degeneracy exists also in the modes of coarse-grained models, but to a much lesser extent than those of all-atom models. In closing, we discuss the implications of the effective degeneracy of normal modes: how it may significantly affect the ways in which normal modes are used in various normal modes

  3. Breathing Mode in Complex Plasmas

    NASA Astrophysics Data System (ADS)

    Fujioka, K.; Henning, C.; Ludwig, P.; Bonitz, M.; Melzer, A.; Vitkalov, S.

    2007-11-01

    The breathing mode is a fundamental normal mode present in Coulomb systems, and may have utility in identifying particle charge and the Debye length of certain systems. The question remains whether this mode can be extended to strongly coupled Yukawa balls [1]. These systems are characterized by particles confined within a parabolic potential well and interacting through a shielded Coulomb potential [2,3]. The breathing modes for a variety of systems in 1, 2, and 3 dimensions are computed by solving the eigenvalue problem given by the dynamical (Hesse) matrix. These results are compared to theoretical investigations that assume a strict definition for a breathing mode within the system, and an analysis is made of the most fitting model to utilize in the study of particular systems of complex plasmas [1,4]. References [1] T.E. Sheridan, Phys. of Plasmas. 13, 022106 (2006)[2] C. Henning et al., Phys. Rev. E 74, 056403 (2006)[3] M. Bonitz et al., Phys. Rev. Lett. 96, 075001 (2006)[4] C. Henning et al., submitted for publication

  4. F-Mode Eikonal Heliotomography

    NASA Astrophysics Data System (ADS)

    de Ridder, S.; Zhao, J.

    2014-12-01

    We investigate 5 days of Doppler measurements geo-tracked for a sunspot. The data is cross -correlated to create time-distance impulse responses of wave propagation in the plasma. We focus on imaging the f-mode (surface gravity mode), which is separated from the other modes by k-ω filtering. Recent developments for surface wave imaging in earth-seismology include the development of an eikonal tomography technique. Eikonal tomography relies on evaluation of the local spatial derivatives of a traveltime surface to directly infer the slowness of wave-propagation. Whereas earth-seismology relies on increasing high signal-to-noise ratio (SNR) by cross-correlating long-time series, helioseismology relies on stacking over geometrically similar virtual sources. We assume there are two symmetries in the geometry of virtual sources around a sunspot. The first is a radial symmetry centered at the sunspot. The second is a radial symmetry of propagation around each virtual source. Because we are interested in the effect of sunspots on wave-propagation, we keep the averaging along the second symmetry axis to a minimum, and rely heavily on averaging each virtual source with equal distance from the sunspot. We will investigate the spatial variation of f-mode dispersion in a radial geometry with the sunspot at the center by creating f-mode velocity maps at different frequencies.

  5. Mode S baseline radar tracking

    NASA Astrophysics Data System (ADS)

    Mancus, E. F.; Baker, L. H.

    1982-11-01

    The baseline performance characteristics of the moving target detector (MTD) and radar data acquisition system (RDAS) as an integral part of the Mode S sensor, were determined. The MTD and RDAS were separately evaluated to determine their capability to provide radar data suitable for utilization by the Mode S sensor and automated radar terminal system (ARTS). The design modifications made to the Mode S sensor to provide the capability of interfacing to either an MTD or RDAS were evaluated to determine if they were in compliance with the Federal Aviation Administration engineering requirement, FAA-ER-240-26. Radar baseline technical performance data was provided to characterize the MTD, RDAS, Mode S, and ARTS. The minimum radar tracking requirements are studied to determine if they are adequate to provide reliable radar track data to an air traffic control facility. It was concluded that the Mode S sensor, when integrated with an MTD-2 radar digitizer, can provide reliable primary radar track data to the ARTS III system for automated radar track acquisition.

  6. The North Pacific Gyre Mode

    NASA Astrophysics Data System (ADS)

    Schneider, N.; di Lorenzo, E.

    2007-12-01

    Discussion of North Pacific Decadal decadal variability has focused primarily on the Pacific Decadal Oscillation, the leading mode of sea surface temperature anomalies north of the tropics. The PDO appears to result from a superposition of SST pattern forced by the North Pacific atmosphere due to its intrinsic dynamics and teleconnected from the tropics, with a regional impact of the ocean circulation in the frontal regions associated with the Kuroshio/Oyashio and their extensions into the interior. Recent modeling, however, suggest that previously unexplained decadal changes of salinity, nutrient upwelling and chlorophyl in the California Current are not dominated by the PDO. Rather, these are associated with a mode of variability associated with wind driven changes of the North Pacific Gyre. Consideration of this mode variability may thus be important to understand present and future variations of the North Pacific ecosystem, and in the interpretation of climate proxies.

  7. Macroscopic (and microscopic) massless modes

    NASA Astrophysics Data System (ADS)

    Abbott, Michael C.; Aniceto, Inês

    2015-05-01

    We study certain spinning strings exploring the flat directions of AdS3 ×S3 ×S3 ×S1, the massless sector cousins of su (2) and sl (2) sector spinning strings. We describe these, and their vibrational modes, using the D(2, 1 ; α) 2 algebraic curve. By exploiting a discrete symmetry of this structure which reverses the direction of motion on the spheres, and alters the masses of the fermionic modes s → κ - s, we find out how to treat the massless fermions which were previously missing from this formalism. We show that folded strings behave as a special case of circular strings, in a sense which includes their mode frequencies, and we are able to recover this fact in the worldsheet formalism. We use these frequencies to calculate one-loop corrections to the energy, with a version of the Beisert-Tseytlin resummation.

  8. Scissors modes: The first overtone

    SciTech Connect

    Hatada, Keisuke; Hayakawa, Kuniko; Palumbo, Fabrizio

    2011-07-15

    Scissors modes were predicted in the framework of the two-rotor model. This model has an intrinsic harmonic spectrum, so that the level above the scissors mode, the first overtone, has excitation energy twice that of the scissors mode. Because the latter is of the order of 3 MeV in the rare-earth region, the energy of the overtone is below threshold for nucleon emission, and its width should remain small enough for the overtone to be observable. We find that B(E2){up_arrow}{sub overtone}=(1/64 {theta}{sub 0}{sup 2})B(E2){up_arrow}{sub scissors}, where {theta}{sub 0} is the zero-point oscillation amplitude, which in the rare-earth region is of order 10{sup -1}.

  9. A-1 Test Stand work

    NASA Technical Reports Server (NTRS)

    2010-01-01

    A structural steel beam to support the new thrust measurement system on the A-1 Test Stand at NASA's John C. Stennis Space Center is lifted to waiting employees for installation. The beam is part of the thrust takeout structure needed to support the new measurement system. Four such beams have been installed at the stand in preparation for installation of the system in upcoming weeks. Operators are preparing the stand for testing the next generation of rocket engines for the U.S. space program.

  10. Tilting mode in nuclear reactions

    SciTech Connect

    Dossing, T.; Randrup, J.

    1986-02-01

    The relation between tilting relaxation and the reaction plane dynamics is discussed, providing an intuitive understanding of the expression for the cross section close to the beam direction, which has recently been derived. Second, the tilting relaxation time and the related wriggling relaxation time are discussed, based upon nucleon exchange transport (window friction). Finally, recent experimental information on the tilting mode relaxation is discussed, and the dynamics of the tilting mode is discussed qualitatively for the three different types of nuclear reactions considered, compound nucleus fission, quasifission, and damped nuclear reactions. 9 refs., 3 figs.

  11. Hydrodynamic modes for granular gases.

    PubMed

    Dufty, James W; Brey, J Javier

    2003-09-01

    The eigenfunctions and eigenvalues of the linearized Boltzmann equation for inelastic hard spheres (d=3) or disks (d=2) corresponding to d+2 hydrodynamic modes are calculated in the long wavelength limit for a granular gas. The transport coefficients are identified and found to agree with those from the Chapman-Enskog solution. The dominance of hydrodynamic modes at long times and long wavelengths is studied via an exactly solvable kinetic model. A collisional continuum is bounded away from the hydrodynamic spectrum, assuring a hydrodynamic description at long times. The bound is closely related to the power law decay of the velocity distribution in the reference homogeneous cooling state. PMID:14524742

  12. Dual-Mode Adhesive Pad

    NASA Technical Reports Server (NTRS)

    Hartz, Leslie

    1994-01-01

    Tool helps worker grip and move along large, smooth structure with no handgrips or footholds. Adheres to surface but easily released by actuating simple mechanism. Includes handle and segmented contact-adhesive pad. Bulk of pad made of soft plastic foam conforming to surface of structure. Each segment reinforced with rib. In sticking mode, ribs braced by side catches. In peeling mode, side catches retracted, and segmented adhesive pad loses its stiffness. Modified versions useful in inspecting hulls of ships and scaling walls in rescue operations.

  13. ‘Introducing Michael Gove to Loïc Wacquant’: Why Social Work Needs Critical Sociology

    PubMed Central

    Michael Garrett, Paul

    2016-01-01

    In 2013, Michael Gove, then Secretary of State for Education and Health in the UK coalition government, criticised social workers for laying insufficient emphasis on the ‘agency’ of individuals and for being too preoccupied with social and economic inequalities. Such a perspective, which is not unique to Gove, needs to be countered by reaffirming the significance of an expansively critical sociology for social work. In this context, the thematic concerns of the French theorist, Loïc Wacquant, illuminates key aspects of social work engagement with clients which Gove and his ideological associates appear intent on ignoring. The issues raised have significant political resonances given the pending UK General Election taking place in May 2015. PMID:27559203

  14. Modelling and simulation of passive Lab-on-a-Chip (LoC) based micromixer for clinical application

    NASA Astrophysics Data System (ADS)

    Saikat, Chakraborty; Sharath, M.; Srujana, M.; Narayan, K.; Pattnaik, Prasant Kumar

    2016-03-01

    In biomedical application, micromixer is an important component because of many processes requires rapid and efficient mixing. At micro scale, the flow is Laminar due to small channel size which enables controlled rapid mixing. The reduction in analysis time along with high throughput can be achieved with the help of rapid mixing. In LoC application, micromixer is used for mixing of fluids especially for the devices which requires efficient mixing. Micromixer of this type of microfluidic devices with a rapid mixing is useful in application such as DNA/RNA synthesis, drug delivery system & biological agent detection. In this work, we design and simulate a microfluidic based passive rapid micromixer for lab-on-a-chip application.

  15. A green laser at 517 nm based on intracavity frequency doubling of the diode-pumped Yb:LO laser

    NASA Astrophysics Data System (ADS)

    Li, Yong-liang; Li, Xiu-fei; Hu, Hong-wei; Hai, Xiao-quan; Liu, Yang; Wang, Jin-nan

    2014-09-01

    We report for the first time, to our knowledge, the diode-pumped continuous-wave (CW) thin-disk Yb3+-doped Lu2O3 (Yb:LO) laser at 1 034 nm and the second-harmonic generation at 517 nm. With a 6.3% output coupler, the maximum output power is 1.17 W under a pump power of 18.5 W. Moreover, the intracavity second-harmonic generation (SHG) is also achieved with power of 193 mW at 517 nm by using an LiB3O5 (LBO) nonlinear crystal. The beam quality factor M 2 is about 1.28. The fluctuation of the output power is about 3% in 1 h.

  16. [Rousseau on the couch. "La nouvelle Héloïse as a key to his childhood trauma].

    PubMed

    Niemeyer, C

    1993-05-01

    Whereas many interpreters and biographers of Rousseau tend to present their subject as a pathological figure, Niemeyer will have no truck with such ascriptions. His reading of Rousseau's epistolary novel Julie ou la Nouvelle Héloïse (1761) draws upon the autobiographical Confessions and reveals that Rousseau uses this novel as a species of self-therapy. In the novel the constellations in which certain scenes recur invite their interpretation as complementary scenes to Rousseau's traumatic "Urszene"--the death of his mother when giving birth to him. In Niemeyer's view, the way in which Rousseau turns his re-working of his childhood trauma to literary account qualifies him as a predecessor of psychoanalysis. PMID:8511325

  17. Nonlinear excitation of polariton cavity modes in ZnO single nanocombs.

    PubMed

    Capeluto, M G; Grinblat, G; Tirado, M; Comedi, D; Bragas, A V

    2014-03-10

    Tunable second harmonic (SH) polaritons have been efficiently generated in ZnO nanocombs, when the material is excited close to half of the band-gap. The nonlinear signal couples to the nanocavity modes, and, as a result, Fabry-Pérot resonances with high Q factors of about 500 are detected. Due to the low effective volume of the confined modes, matter-light interaction is very much enhanced. This effect lowers the velocity of the SH polariton in the material by 50 times, and increases the SH confinement inside the nanocavity due to this higher refractive index. We also show that the SH phase-matching condition is achieved through LO-phonon mediation. Finally, birrefringence of the crystal produces a strong SH intensity dependence on the input polarization, with a high polarization contrast, which could be used as a mechanism for light switching in the nanoscale. PMID:24663874

  18. Phonon-roton modes of liquid 4He beyond the roton in MCM-41

    SciTech Connect

    Azuah, Richard T; Omar Diallo, Souleymane; Adams, Mark A.; Kirichek, Oleg; Glyde, Henry R

    2013-01-01

    We present neutron scattering measurements of the phonon-roton (P-R) mode of superfluid 4He confined in 47 A MCM-41 at T = 0.5 K at wave vectors, Q, beyond the roton wave vector (QR = 1.92 A-1). Measurements beyond the roton require access to high wave vectors (up to Q = 4 A-1) with excellent energy resolution and high statistical precision. The present results show for the first time that at T = 0.5 K the P-R mode in MCM-41 extends out to wave-vector Q 3.6 A-1 with the same energy and zero width (within precision) as observed in bulk superfluid 4He. Layer modes in the roton region are also observed. Specifically, the P-R mode energy, !Q, increases with Q for Q > QR and reaches a plateau at a maximum energy !Q = 2 where is the roton energy, = 0.74 0.01 meV in MCM-41. This upper limit means the P-R mode decays to two rotons when its energy exceeds 2 . It also means that the P-R mode does not decay to two layers modes. If the P-R could decay to two layer modes, !Q would plateau at a lower energy, !Q = 2 L where L = 0.60 meV is the energy of the roton like minimum of the layer mode. The observation of the P-R mode with energy up to 2 shows that the P-R mode and the layer modes are independent modes with apparently little interaction between them.

  19. Observation of the distribution of heavy neutral atoms in the IBEX-Lo all-sky maps

    NASA Astrophysics Data System (ADS)

    Park, J.; Kucharek, H.; Moebius, E.

    2014-12-01

    We investigate the spatial distribution of heavy energetic neutral atoms, mostly oxygen and neon, in the sky maps taken with the Interstellar Boundary Explorer (IBEX) in 2009 - 2011. The IBEX-Lo sensor, one of two highly sensitive single-pixel cameras on the IBEX spacecraft, measures neutral particles within an energy range from 0.01 to 2 keV. In the time-of-flight detector of IBEX-Lo these neutral atoms can be identified as hydrogen or heavier atoms, such as oxygen. These measurements have provided all-sky maps of neutral hydrogen and oxygen. The dominant feature in these maps is the interstellar oxygen and neon gas flow. Its peak location is approximately consistent with the interstellar helium gas flow (Möbius et al., 2009, Science, 326, 969). The flow distribution is distributed over 210° - 240° ecliptic longitude and -6° - 12° ecliptic latitude. Another prominent feature in the oxygen sky maps at 0.2 to 0.8 keV is an extended tail of the oxygen signal toward lower longitude and higher positive latitude (180° - 210° ecliptic longitude and 0° - 24° ecliptic latitude). The measured peak rates in the extended tail is 3 - 5% of the maximum count rate in the primary oxygen and neon gas flow, but is four times higher than any other surrounding oxygen signals. The extended tail may indicate the secondary component of the interstellar oxygen, which is likely generated by charge exchange between local O+ ions and interstellar neutral H in the outer heliosheath. In this poster, we will discuss these two most prominent features in the oxygen sky maps and their implications for the source and the mechanism generating an extended tail in the oxygen signal.

  20. Doppler imaging of the young late-type star LO Pegasi (BD+22°4409) in 2003 September

    NASA Astrophysics Data System (ADS)

    Piluso, N.; Lanza, A. F.; Pagano, I.; Lanzafame, A. C.; Donati, J.-F.

    2008-06-01

    A Doppler image of the zero-age main-sequence (ZAMS) late-type rapidly rotating star LO Pegasi, based on spectra acquired between 2003 September 12 and 15 is presented. The least-squares deconvolution technique is applied to enhance the signal-to-noise ratio of the mean rotational broadened line profiles extracted from the observed spectra. In the present application, an unbroadened spectrum is used as a reference, instead of a simple line list, to improve the deconvolution technique applied to extract the mean profiles. The reconstructed image is similar to those previously obtained from observations taken in 1993 and 1998, and shows that LO Peg photospheric activity is dominated by high-latitude spots with a non-uniform polar cap. The latter seems to be a persistent feature as it has been observed since 1993 with little modifications. Small spots, observed between ~10° and ~60° of latitude, appears to be different with respect to those present in the 1993 and 1998 maps. Based on observations made with the Italian Telescopio Nazionale Galileo operated on the island of La Palma by the Centro Galileo Galilei of INAF (Istituto Nazionale di Astrofisica) at the Spanish Observatorio del Roque del los Muchachos of the Instituto de Astrofísica de Canarias. E-mail: nicolo.piluso@oact.inaf.it (NP); nuccio.lanza@oact.inaf.it (AFL); isabella.pagano@oact.inaf.it (IP); alessandro.lanzafame@oact.inaf.it (ACL); donati@ast.obs-mip.fr (J-FD)

  1. Evaluation of imaging performance of a taper optics CCD; FReLoN' camera designed for medical imaging.

    PubMed

    Coan, Paola; Peterzol, Angela; Fiedler, Stefan; Ponchut, Cyril; Labiche, Jean Claude; Bravin, Alberto

    2006-05-01

    The purpose of this work was to assess the imaging performance of an indirect conversion detector (taper optics CCD; FReLoN' camera) in terms of the modulation transfer function (MTF), normalized noise power spectrum (NNPS) and detective quantum efficiency (DQE). Measurements were made with a synchrotron radiation laminar beam at various monochromatic energies in the 20-51.5 keV range for a gadolinium-based fluorescent screen varying in thickness; data acquisition and analysis were made by adapting to this beam geometry protocols used for conventional cone beams. The pre-sampled MTFs of the systems were measured using an edge method. The NNPS of the systems were determined for a range of exposure levels by two-dimensional Fourier analysis of uniformly exposed radiographs. The DQEs were assessed from the measured MTF, NNPS, exposure and incoming number of photons. The MTF, for a given screen, was found to be almost energy independent and, for a given energy, higher for the thinnest screen. At 33 keV and for the 40 (100) microm screen, at 10% the MTF is 9.2 (8.6) line-pairs mm(-1). The NNPS was found to be different in the two analyzed directions in relation to frequency. Highest DQE values were found for the combination 100 microm and 25 keV (0.5); it was still equal to 0.4 at 51.5 keV (above the gadolinium K-edge). The DQE is limited by the phosphor screen conversion yield and by the CCD efficiency. At the end of the manuscript the results of the FReLoN characterization and those from a selected number of detectors presented in the literature are compared. PMID:16645252

  2. Simulating the Compton-Getting effect for hydrogen flux measurements: Implications for IBEX-Hi and -Lo observations

    SciTech Connect

    Zirnstein, E. J.; Heerikhuisen, J.; McComas, D. J.; Schwadron, N. A.

    2013-12-01

    The Interstellar Boundary EXplorer (IBEX), launched in 2008 October, has improved our understanding of the solar wind-local interstellar medium interaction through its detection of neutral atoms, particularly that of hydrogen (H). IBEX is able to create full maps of the sky in six-month intervals as the Earth orbits the Sun, detecting H with energies between ∼0.01 and 6 keV. Due to the relative motion of IBEX to the solar inertial frame, measurements made in the spacecraft frame introduce a Compton-Getting (CG) effect, complicating measurements at the lowest energies. In this paper we provide results from a numerical simulation that calculates fluxes of H atoms at 1 AU in the inertial and spacecraft frames (both ram and anti-ram), at energies relevant to IBEX-Hi and -Lo. We show theory behind the numerical simulations, applying a simple frame transformation to derived flux equations that provides a straightforward way to simulate fluxes in the spacecraft frame. We then show results of H energetic neutral atom fluxes simulated at IBEX-Hi energy passbands 2-6 in all frames, comparing with IBEX-Hi data along selected directions, and also show results simulated at energies relevant to IBEX-Lo. Although simulations at IBEX-Hi energies agree reasonably well with the CG correction method used for IBEX-Hi data, we demonstrate the importance of properly modeling low energy H fluxes due to inherent complexities involved with measurements made in moving frames, as well as dynamic radiation pressure effects close to the Sun.

  3. Preliminary base heating environments for a generalized ALS LO2/LH2 launch vehicle, appendix 1 and 2

    NASA Technical Reports Server (NTRS)

    Bender, Robert L.; Reardon, John E.

    1989-01-01

    A secondary objective of contract NAS8-39141 is to provide base heating assessments, as required, to support Advanced Launch System (ALS) preliminary launch vehicle and propulsion system design studies. The ALS propulsion systems integration working group meeting (No. 3) recently completed in San Diego, California, focused attention on the need for base heating environment determination to provide preliminary requirements for LO2/LH2 propulsion systems currently being considered for ALS. We were requested to provide these environments for a range of possible propellant mixture and nozzle area ratios. Base heating environments can only be determined as a function of altitude when the engine operating conditions and vehicle base region geometry (engine arrangement) are known. If time dependent environments are needed to assess thermal loads, a trajectory must also be provided. These parameters are not fixed at this time since the ALS configurations and propulsion operating conditions are varied and continue to be studied by Phase B contractors. Therefore, for this study, a generalized LO2/LH2 system was selected along with a vehicle configuration consisting of a seven-engine booster and a three-engine core. MSFC provided guidance for the selection. We also selected a limited number of body points on the booster and core vehicles and engines for the environment estimates. Environments at these locations are representative of maximum heating conditions in the base region and are provided as a function of altitude only. Guidelines and assumptions for this assessment, methodology for determining the environments, and preliminary results are provided in this technical note. Refinements in the environments will be provided as the ALS design matures.

  4. Experimental Investigation of Augmented Spark Ignition of a LO2/LCH4 Reaction Control Engine at Altitude Conditions

    NASA Technical Reports Server (NTRS)

    Kleinhenz, Julie; Sarmiento, Charles; Marshall, William

    2012-01-01

    The use of nontoxic propellants in future exploration vehicles would enable safer, more cost-effective mission scenarios. One promising green alternative to existing hypergols is liquid methane (LCH4) with liquid oxygen (LO2). A 100 lbf LO2/LCH4 engine was developed under the NASA Propulsion and Cryogenic Advanced Development project and tested at the NASA Glenn Research Center Altitude Combustion Stand in a low pressure environment. High ignition energy is a perceived drawback of this propellant combination; so this ignition margin test program examined ignition performance versus delivered spark energy. Sensitivity of ignition to spark timing and repetition rate was also explored. Three different exciter units were used with the engine s augmented (torch) igniter. Captured waveforms indicated spark behavior in hot fire conditions was inconsistent compared to the well-behaved dry sparks. This suggests that rising pressure and flow rate increase spark impedance and may at some point compromise an exciter s ability to complete each spark. The reduced spark energies of such quenched deliveries resulted in more erratic ignitions, decreasing ignition probability. The timing of the sparks relative to the pressure/flow conditions also impacted the probability of ignition. Sparks occurring early in the flow could trigger ignition with energies as low as 1 to 6 mJ, though multiple, similarly timed sparks of 55 to 75 mJ were required for reliable ignition. Delayed spark application and reduced spark repetition rate both correlated with late and occasional failed ignitions. An optimum time interval for spark application and ignition therefore coincides with propellant introduction to the igniter.

  5. Single-mode fiber, velocity interferometry

    SciTech Connect

    Krauter, K. G.; Jacobson, G. F.; Patterson, J. R.; Nguyen, J. H.; Ambrose, W. P.

    2011-04-15

    In this paper, we describe a velocity interferometer system based entirely on single-mode fiber optics. This paper includes a description of principles used in developing the single-mode velocity interferometry system (SMV). The SMV design is based on polarization-insensitive components. Polarization adjusters are included to eliminate the effects of residual birefringence and polarization dependent losses in the interferometers. Characterization measurements and calibration methods needed for data analysis and a method of data analysis are described. Calibration is performed directly using tunable lasers. During development, we demonstrated its operation using exploding-foil bridge-wire fliers up to 200 m/s. In a final test, we demonstrated the SMV in a gas gun experiment up to 1.2 km/sec. As a basis for comparison in the gas gun experiment, we used another velocimetry technique that is also based on single-mode fiber optics: photonic Doppler velocimetry (PDV). For the gas gun experiment, we split the light returned from a single target spot and performed a direct comparison of the homodyne (SMV) and heterodyne (PDV) techniques concurrently. The two techniques had a negligible mean difference and a 1.5% standard deviation in the one-dimensional shock zone. Within one interferometer delay time after a sudden Doppler shift, a SMV unencumbered by multimode-fiber dispersion exhibits two color beats. These beats have the same period as PDV beats--this interference occurs between the ''recently'' shifted and ''formerly unshifted'' paths within the interferometer. We believe that recognizing this identity between homodyne and heterodyne beats is novel in the shock-physics field. SMV includes the conveniences of optical fiber, while removing the time resolution limitations associated with the multimode delivery fiber.

  6. Single-mode fiber, velocity interferometry.

    PubMed

    Krauter, K G; Jacobson, G F; Patterson, J R; Nguyen, J H; Ambrose, W P

    2011-04-01

    In this paper, we describe a velocity interferometer system based entirely on single-mode fiber optics. This paper includes a description of principles used in developing the single-mode velocity interferometry system (SMV). The SMV design is based on polarization-insensitive components. Polarization adjusters are included to eliminate the effects of residual birefringence and polarization dependent losses in the interferometers. Characterization measurements and calibration methods needed for data analysis and a method of data analysis are described. Calibration is performed directly using tunable lasers. During development, we demonstrated its operation using exploding-foil bridge-wire fliers up to 200 m/s. In a final test, we demonstrated the SMV in a gas gun experiment up to 1.2 km/sec. As a basis for comparison in the gas gun experiment, we used another velocimetry technique that is also based on single-mode fiber optics: photonic Doppler velocimetry (PDV). For the gas gun experiment, we split the light returned from a single target spot and performed a direct comparison of the homodyne (SMV) and heterodyne (PDV) techniques concurrently. The two techniques had a negligible mean difference and a 1.5% standard deviation in the one-dimensional shock zone. Within one interferometer delay time after a sudden Doppler shift, a SMV unencumbered by multimode-fiber dispersion exhibits two color beats. These beats have the same period as PDV beats-this interference occurs between the "recently" shifted and "formerly unshifted" paths within the interferometer. We believe that recognizing this identity between homodyne and heterodyne beats is novel in the shock-physics field. SMV includes the conveniences of optical fiber, while removing the time resolution limitations associated with the multimode delivery fiber. PMID:21529042

  7. Correlation between surface phonon mode and luminescence in nanocrystalline CdS thin films: An effect of ion beam irradiation

    SciTech Connect

    Kumar, Pragati Agarwal, Avinash; Saxena, Nupur; Singh, Fouran; Gupta, Vinay

    2014-07-28

    The influence of swift heavy ion irradiation (SHII) on surface phonon mode (SPM) and green emission in nanocrystalline CdS thin films grown by chemical bath deposition is studied. The SHII of nanocrystalline CdS thin films is carried out using 70 MeV Ni ions. The micro Raman analysis shows that asymmetry and broadening in fundamental longitudinal optical (LO) phonon mode increases systematically with increasing ion fluence. To analyze the role of phonon confinement, spatial correlation model (SCM) is fitted to the experimental data. The observed deviation of SCM to the experimental data is further investigated by fitting the micro Raman spectra using two Lorentzian line shapes. It is found that two Lorentzian functions (LFs) provide better fitting than SCM fitting and facilitate to identify the contribution of SPM in the observed distortion of LO mode. The behavior of SPM as a function of ion fluence is studied to correlate the observed asymmetry (Γ{sub a}/Γ{sub b}) and full width at half maximum of LO phonon mode and to understand the SHII induced enhancement of SPM. The ion beam induced interstitial and surface state defects in thin films, as observed by photoluminescence (PL) spectroscopy studies, may be the underlying reason for enhancement in SPM. PL studies also show enhancement in green luminescence with increase in ion fluence. PL analysis reveals that the variation in population density of surface state defects after SHII is similar to that of SPM. The correlation between SPM and luminescence and their dependence on ion irradiation fluence is explained with the help of thermal spike model.

  8. Laser Mode Structure Experiments for Undergraduate Laboratories.

    ERIC Educational Resources Information Center

    Phillips, Richard A.; Gehrz, Robert D.

    Experiments dealing with laser mode structure are presented which are suitable for an upper division undergraduate laboratory. The theory of cavity modes is summarized. The mode structure of the radiation from a helium-neon laser is measured by using a photodiode detector and spectrum analyzer to detect intermode beating. Off-axial modes can be…

  9. Dual mode nuclear rocket system applications.

    NASA Technical Reports Server (NTRS)

    Boretz, J. E.; Bell, J. M.; Plebuch, R. K.; Priest, C. C.

    1972-01-01

    Mission areas where the dual-mode nuclear rocket system is superior to nondual-mode systems are demonstrated. It is shown that the dual-mode system is competitive with the nondual-mode system even for those specific missions and particular payload configurations where it does not have a clear-cut advantage.

  10. Collisionless Trapped Electron Mode Turbulence

    NASA Astrophysics Data System (ADS)

    Lang, Jianying; Chen, Yang; Parker, Scott

    2006-10-01

    Collisionless Trapped Electron Mode (CTEM) turbulence is a likely canidate for explaining anomolous transport in tokamak discharges that have a strong density gradient relative to the ion temperature gradient. Here, CTEM turbulence is investigated using the Gyrokinetic δf GEM code. GEM is electromagnetic, includes full drift-kinetic electrons, generaly axisymmetric equilbria, collisions and minority species. Here, the flux-tube limit is taken and β is so small that the simulations are essentially electrostatic. Linear theory predicts that the instability occurs at √2ɛRLn>1, which agrees very well with the simulation results. With increasing density gradient, it is observed that the most unstable mode transitions from a CTEM to drift wave mode and the short-wavelength modes are most unstable ( 2 > kρi> 1). Nonlinear simulations are underway to address the parametric dependence of particle and energy transport. The importance of zonal flows for CTEM turbulence, is still not well understood and is under investigation. D. R. Ernst et. al., Phys. Plasma 11 (2004) 2637 T. Dannert and F. Jenko, Phys. Plasma 12 (2005) 072309 R. Gatto et. al., Phys. Plasma 13 (2006) 022306 Y. Chen and S. E. Parker, J. Comput. Phys. 189 (2003) 463 Y. Chen ad S.E. Parker, accepted, to appear in J. Comput. Phys. (2006) J. Wesson (1997) Tokamaks, Oxford Science

  11. Terra is in NORMAL Mode

    Atmospheric Science Data Center

    2016-02-23

    ... 22, 2016.  TERRA has recovered from Safe Hold and is now in Normal mode. CERES will hold their CAM Wednesday morning and will ... . You can learn more about this mission at the Terra web site. The Flight Operations Team is working on resolving the issue as ...

  12. Microtearing modes in tokamak discharges

    NASA Astrophysics Data System (ADS)

    Rafiq, T.; Weiland, J.; Kritz, A. H.; Luo, L.; Pankin, A. Y.

    2016-06-01

    Microtearing modes (MTMs) have been identified as a source of significant electron thermal transport in tokamak discharges. In order to describe the evolution of these discharges, it is necessary to improve the prediction of electron thermal transport. This can be accomplished by utilizing a model for transport driven by MTMs in whole device predictive modeling codes. The objective of this paper is to develop the dispersion relation that governs the MTM driven transport. A unified fluid/kinetic approach is used in the development of a nonlinear dispersion relation for MTMs. The derivation includes the effects of electrostatic and magnetic fluctuations, arbitrary electron-ion collisionality, electron temperature and density gradients, magnetic curvature, and the effects associated with the parallel propagation vector. An iterative nonlinear approach is used to calculate the distribution function employed in obtaining the nonlinear parallel current and the nonlinear dispersion relation. The third order nonlinear effects in magnetic fluctuations are included, and the influence of third order effects on a multi-wave system is considered. An envelope equation for the nonlinear microtearing modes in the collision dominant limit is introduced in order to obtain the saturation level. In the limit that the mode amplitude does not vary along the field line, slab geometry, and strong collisionality, the fluid dispersion relation for nonlinear microtearing modes is found to agree with the kinetic dispersion relation.

  13. Current Mode Logic Fan Out

    2011-05-07

    Current mode logic is used in high speed timing systems for particle accelerators due to the fast rise time of the electrical signal. This software provides the necessary documentation to produce multiple copies of a single input for distribution to multiple devices. This software supports the DOE mission by providing a method for producing high speed signals in accelerator timing systems.

  14. Students' Perceptions of Study Modes

    ERIC Educational Resources Information Center

    Hagel, Pauline; Shaw, Robin N.

    2006-01-01

    This paper reports on a survey of how Australian undergraduate students perceive the benefits of broad study modes: face-to-face classes, web-based study, and print-based study. Two benefit types were identified through factor analysis: engagement and functionality. Respondents rated face-to-face classes highest on engagement and print-based study…

  15. Modes of Greetings in Nepali.

    ERIC Educational Resources Information Center

    Giri, Ram Ashish

    The greeting systems in Nepali are derived from the Hindu ethos and religious culture, and can be traced back to Hindu sacred writing. However, as tied to conventions as they are, these systems are also the product of an interplay of socio-cultural factors. A study found that despite exposure to education and Western culture, Nepali modes of…

  16. Single mode glass fiber welding

    NASA Technical Reports Server (NTRS)

    Nelson, M. D.; Fearnehough, H. T.; Goldstein, R.; Goss, W. C.

    1979-01-01

    The electric-arc welding of commercially available single-mode optical fiber has been demonstrated. A mean transmission of 92% and a maximum transmission of 98% are reported for welds of fiber waveguide of 4.5 microns core diameter.

  17. Mode of Action of Glyphosate

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Although glyphosate is the most used and studied herbicide in the world, the available information is not enough to fully understand its mode of action. The molecular site of action of glyphosate is the enzyme 5-enolpyruvlyshikimate-3-phosphate synthase (EPSPS). It is the only known compound that ...

  18. Three-Mode Orthomax Rotation.

    ERIC Educational Resources Information Center

    Kiers, Henk A. L.

    1997-01-01

    Provides a fully flexible approach for orthomax rotation of the core to simple structure with respect to three modes simultaneously. Computationally the approach relies on repeated orthomax rotation applied to supermatrices containing the frontal, lateral, or horizontal slabs, respectively. Exemplary analyses illustrate the procedure. (Author/SLD)

  19. Modes of clustered star formation

    NASA Astrophysics Data System (ADS)

    Pfalzner, S.; Kaczmarek, T.; Olczak, C.

    2012-09-01

    Context. The recent realization that most stars form in clusters, immediately raises the question of whether star and planet formation are influenced by the cluster environment. The stellar density in the most prevalent clusters is the key factor here. Whether dominant modes of clustered star formation exist is a fundamental question. Using near-neighbour searches in young clusters, Bressert and collaborators claim this not to be the case. They conclude that - at least in the solar neighbourhood - star formation is continuous from isolated to densely clustered environments and that the environment plays a minor role in star and planet formation. Aims: We investigate under which conditions near-neighbour searches in young clusters can distinguish between different modes of clustered star formation. Methods: Model star clusters with different memberships and density distributions are set up and near-neighbour searches are performed. We investigate the influence of the combination of different cluster modes, observational biases, and types of diagnostic on the results. Results: We find that the specific cluster density profile, the relative sample sizes, the limitations of the observation, and the choice of diagnostic method decide, whether modelled modes of clustered star formation are detected by near-neighbour searches. For density distributions that are centrally concentrated but span a wide density range (for example, King profiles), separate cluster modes are only detectable under ideal conditions (sample selection, completeness) if the mean density of the individual clusters differs by at least a factor of ~65. Introducing a central cut-off can lead to an underestimate of the mean density by more than a factor of ten especially in high density regions. The environmental effect on star and planet formation is similarly underestimated for half of the population in dense systems. Conclusions: Local surface-density distributions are a very useful tool for single

  20. Mode selective directional coupler for NLC

    SciTech Connect

    Tantawi, S.G.

    1994-10-01

    The design method for a high power, X-band, 50 dB, circular to rectangular directional coupler is presented. The circular guide is over moded and is intended to operate in TE{sub 01} mode. The rectangular guide operates at the fundamental TE{sub 10} mode. A small percentage of higher order modes in the circular guide can cause considerable errors in the measurements because the magnitude of the axial magnetic field of these modes is higher than that of the operating mode, especially near their cutoff. We used a Hamming window patten for the coupling slots to achieve mode selectivity. Comparison of theory and experiment will be presented.

  1. Electron Temperature Fluctuations Associated with the Weakly Coherent Mode in the Edge of I-mode Plasmas

    NASA Astrophysics Data System (ADS)

    White, A. E.; Phillips, P.; Whyte, D. G.; Hubbard, A. E.; Sung, C.; Hughes, J. W.; Dominguez, A.; Terry, J.; Cziegler, I.

    2012-03-01

    New measurements of electron temperature fluctuations associated with the weakly coherent mode (WCM) during improved mode, or I-mode plasmas at Alcator C-Mod are presented in this poster [A. E. White, et al. Nuclear Fusion, 51, 113005 (2011)]. The measurements are made with a 32-channel, high-resolution profile ECE radiometer. The WCM electron temperature fluctuations are localized to a 1 cm region inside the last closed flux surface. The WCM electron temperature fluctuation level is measured in several different I-mode discharges and is in the range 1-2%, which is up to an order of magnitude smaller than the WCM density fluctuation level. The WCM edge fluctuations observed in I-mode are believed to play a role in increasing particle transport but not energy transport in the edge of I-mode plasmas. The large difference between normalized density and electron temperature fluctuation amplitudes provides new evidence that the WCM fluctuations can separately affect energy and particle transport.

  2. Silicon waveguide based TE mode converter.

    PubMed

    Zhang, Jing; Liow, Tsung-Yang; Yu, Mingbin; Lo, Guo-Qiang; Kwong, Dim-Lee

    2010-11-22

    A silicon waveguide based TE mode converter was designed for the mode conversion between a horizontal waveguide and vertical waveguide in the two-layer structure waveguide based polarization diversity circuit. The TE mode converter's performance was studied. The polarization mode converter with minimum length of 5 μm was demonstrated to provide the TE mode conversion while maintaining the polarization status. The insertion loss at the transition region was less than 2 dB. PMID:21164874

  3. INVESTIGATION OF A PLASMA MODE IN EBTS.

    SciTech Connect

    HERSHCOVITCH,A.

    2000-11-06

    A plasma related mode has been identified when EBTS operated with long trap length. The mode frequency scaling showed monotonic increased with confinement time. Initial scaling qualitatively suggested the mode to an electron beam driven ion cyclotron instability. However, a more quantitative evaluation is indicative of a drift mode. Nevertheless, the possibility of a structure mode, though unlikely, can not be completely excluded. The process of proper instability identification and stabilization is described.

  4. MicroRNA-674-5p/5-LO axis involved in autoimmune reaction of Concanavalin A-induced acute mouse liver injury.

    PubMed

    Su, Kunkai; Wang, Qi; Qi, Luoyang; Hua, Dasong; Tao, Jingjing; Mangan, Connor J; Lou, Yijia; Li, Lanjuan

    2016-09-01

    Autoimmune hepatitis is characterized, in part, by the pathways involving cysteinyl-leukotriene metabolites of arachidonic acid, the dynamics of which remain unclear. Here, we explored post-transcriptional regulation in the 5-lipoxygenase (5-LO) pathway of arachidonic acid in a Concanavalin A (Con A) induced mouse model. We found that Con A administration lead to 5-LO overexpression and cysteinyl-leukotriene release in early hepatic injury, which was attenuated by cyclosporin A pretreatment. Subsequent microarray and qRT-PCR analysis further showed that microRNA-674-5p (miR-674-5p) displayed a significant decrease in expression in Con A-damaged liver. Noting that miR-674-5p harbors a potential binding region for 5-LO, we further transfected hepatic cell lines with overexpressing miR-674-5p mimic and discovered a negative regulating effect of miR-674-5p on 5-LO expression in the presence of IL-6 or TNF-α. These findings suggest that miR-674-5p might be a negative regulator in 5-LO mediated autoimmune liver injury, representing a compelling avenue towards future therapeutic interventions. PMID:27313091

  5. Dual-cavity mode converter for a fundamental mode output in an over-moded relativistic backward-wave oscillator

    SciTech Connect

    Li, Jiawei; Huang, Wenhua; Xiao, Renzhen; Bai, Xianchen; Zhang, Yuchuan; Zhang, Xiaowei; Shao, Hao; Chen, Changhua; Zhu, Qi

    2015-03-16

    A dual-cavity TM{sub 02}–TM{sub 01} mode converter is designed for a dual-mode operation over-moded relativistic backward-wave oscillator. With the converter, the fundamental mode output is achieved. Particle-in-cell simulation shows that the efficiency of beam-wave conversion was over 46% and a pureTM{sub 01} mode output was obtained. Effects of end reflection provided by the mode converter were studied. Adequate TM{sub 01} mode feedback provided by the converter enhances conversion efficiency. The distance between the mode converter and extraction cavity critically affect the generation of microwaves depending on the reflection phase of TM{sub 01} mode feedback.

  6. Decoherence Patterns of Topological Qubits from Majorana Modes

    NASA Astrophysics Data System (ADS)

    Chao, Sung Po; Ho, Shih Hao; Chou, Chung Hsien; Lin, Feng Li

    2015-03-01

    We investigate the decoherence patterns of topological qubits in contact with the environment. Each topological qubit is made of two Majorana modes of a 1D Kitaev's chain. These two Majorana modes weakly interact with the fermionic/bosonic environments. We find the topological qubits decohere completely in the Ohmic and sub-Ohmic environments but not in the super-Ohmic ones. Though the fermion parities of the topological qubits cannot prevent the qubit states from decoherence in the sub-Ohmic environments, it can prevent the qubits turning into Gibbs state. We also study the cases in which each Majorana mode couples to different Ohmic-like environments and the time dependence of concurrence for two topological qubits. FLL is supported by Taiwan's NSC Grants (Grant NO. 100-2811-M-003-011 and 100-2918-I-003-008). All authors acknowledge the support by NCTS.

  7. Hypersonic modes in nanophononic semiconductors.

    PubMed

    Hepplestone, S P; Srivastava, G P

    2008-09-01

    Frequency gaps and negative group velocities of hypersonic phonon modes in periodically arranged composite semiconductors are presented. Trends and criteria for phononic gaps are discussed using a variety of atomic-level theoretical approaches. From our calculations, the possibility of achieving semiconductor-based one-dimensional phononic structures is established. We present results of the location and size of gaps, as well as negative group velocities of phonon modes in such structures. In addition to reproducing the results of recent measurements of the locations of the band gaps in the nanosized Si/Si{0.4}Ge{0.6} superlattice, we show that such a system is a true one-dimensional hypersonic phononic crystal. PMID:18851224

  8. Vainshtein solutions without superluminal modes

    NASA Astrophysics Data System (ADS)

    Gabadadze, Gregory; Kimura, Rampei; Pirtskhalava, David

    2015-06-01

    The Vainshtein mechanism suppresses the fifth force at astrophysical distances, while enabling it to compete with gravity at cosmological scales. Typically, Vainshtein solutions exhibit superluminal perturbations. However, a restricted class of solutions with special boundary conditions was shown to be devoid of the faster-than-light modes. Here we extend this class by finding solutions in a theory of quasidilaton, amended by derivative terms consistent with its symmetries. Solutions with Minkowski asymptotics are not stable, while the ones that exhibit the Vainshtein mechanism by transitioning to cosmological backgrounds are free of ghosts, tachyons, gradient instability, and superluminality, for all propagating modes present in the theory. These solutions require a special choice of the strength and signs of nonlinear terms, as well as a choice of asymptotic cosmological boundary conditions.

  9. Coulomb blockade with neutral modes.

    PubMed

    Kamenev, Alex; Gefen, Yuval

    2015-04-17

    We study transport through a quantum dot in the fractional quantum Hall regime with filling factors ν=2/3 and ν=5/2, weakly coupled to the leads. We account for both injection of electrons to or from the leads, and quasiparticle rearrangement processes between the edge and the bulk of the quantum dot. The presence of neutral modes introduces topological constraints that modify qualitatively the features of the Coulomb blockade (CB). The periodicity of CB peak spacings doubles and the ratio of spacing between adjacent peaks approaches (in the low temperature and large dot limit) a universal value: 2∶1 for ν=2/3 and 3∶1 for ν=5/2. The corresponding CB diamonds alternate their width in the direction of the bias voltage and allow for the determination of the neutral mode velocity, and of the topological numbers associated with it. PMID:25933323

  10. Observations of pressure gradient driven m = 1 internal kink mode in EAST tokamak

    SciTech Connect

    Xu Liqing; Hu Liqun; Chen Kaiyun; Li Erzhong; Wang Fudi; Xu Ming; Duan Yanmin; Shi Tonghui; Zhang Jizong; Zhou Ruijie; Chen Yebin

    2012-12-15

    Pressure gradient driven m = 1 internal kink mode destabilization that follows an L-H transition is observed in the operational region of the EAST tokamak, which manifests in periodic oscillations in soft x-ray (SXR) and Mirnov coil signals. Using tomography with the high resolution soft x-ray detection array, we find that the rotation direction of the 1/1 kink mode is in the ion diamagnetic drift direction in poloidal cross-section. A large displacement of the hot core is attributable to the shift of the 1/1 internal kink mode. In contrast to stationary oscillations with fixed frequency, various frequency chirping behavior is observed with this 1/1 kink mode. Furthermore, we also occasionally observe that a 2/1 neoclassical tearing mode (NTM) is triggered by a 1/1 internal kink mode via mode coupling in a high-performance plasma. The spatial structure of a 2/2 mode, which is the harmonic mode of the 1/1 kink mode, is also presented in this paper. Large amounts of medium-Z impurities accumulate in the central plasma region where the 1/1 kink mode instability bursts. Finally, we also find that the frequency beating associated with a 1/1 kink mode is a consequence of plasma rotation. Based on all of these observations, we propose that the plasma pressure gradient, the driving force in kink modes, is plausibly the product of an intense concentration of impurities, which are related to plasma rotation.

  11. Observations of pressure gradient driven m = 1 internal kink mode in EAST tokamak

    NASA Astrophysics Data System (ADS)

    Xu, Liqing; Hu, Liqun; Chen, Kaiyun; Li, Erzhong; Wang, Fudi; Xu, Ming; Duan, Yanmin; Shi, Tonghui; Zhang, Jizong; Zhou, Ruijie; Chen, Yebin

    2012-12-01

    Pressure gradient driven m = 1 internal kink mode destabilization that follows an L-H transition is observed in the operational region of the EAST tokamak, which manifests in periodic oscillations in soft x-ray (SXR) and Mirnov coil signals. Using tomography with the high resolution soft x-ray detection array, we find that the rotation direction of the 1/1 kink mode is in the ion diamagnetic drift direction in poloidal cross-section. A large displacement of the hot core is attributable to the shift of the 1/1 internal kink mode. In contrast to stationary oscillations with fixed frequency, various frequency chirping behavior is observed with this 1/1 kink mode. Furthermore, we also occasionally observe that a 2/1 neoclassical tearing mode (NTM) is triggered by a 1/1 internal kink mode via mode coupling in a high-performance plasma. The spatial structure of a 2/2 mode, which is the harmonic mode of the 1/1 kink mode, is also presented in this paper. Large amounts of medium-Z impurities accumulate in the central plasma region where the 1/1 kink mode instability bursts. Finally, we also find that the frequency beating associated with a 1/1 kink mode is a consequence of plasma rotation. Based on all of these observations, we propose that the plasma pressure gradient, the driving force in kink modes, is plausibly the product of an intense concentration of impurities, which are related to plasma rotation.

  12. Continuous scanning mode for ptychography

    SciTech Connect

    Clark, Jesse N.; Huang, Xiaojing; Harder, Ross J.; Robinson, Ian K.

    2014-01-01

    Here, we outline how ptychographic imaging can be performed without the need for discrete scan positions. Through an idealized experiment, we demonstrate how a discrete-position scan regime can be replaced with a continuously scanned one with suitable modification of the reconstruction scheme based on coherent modes. Furthermore, the impact of this is that acquisition times can be reduced, significantly aiding ptychographic imaging with x rays, electrons, or visible light.

  13. Continuous scanning mode for ptychography

    SciTech Connect

    Clark, Jesse N.; Huang, Xiaojing; Harder, Ross; Robinson, Ian K.

    2014-10-15

    We outline how ptychographic imaging can be performed without the need for discrete scan positions. Through an idealized experiment, we demonstrate how a discrete-position scan regime can be replaced with a continuously scanned one with suitable modification of the reconstruction scheme based on coherent modes. The impact of this is that acquisition times can be reduced, significantly aiding ptychographic imaging with x rays, electrons, or visible light.

  14. Production of a_1 in heavy meson decays

    NASA Astrophysics Data System (ADS)

    Wang, Wei; Zhao, Zhen-Xing

    2016-02-01

    In this work, we study various decays of heavy B / D mesons into the a_1(1260), based on the form factors derived in different nonperturbative or factorization approaches. These decay modes are helpful to explore the dynamics in the heavy to light transitions. Meanwhile they can also provide insights to a newly discovered state, the a_1(1420) with I^G(J^{PC})= 1^-(1^{++}) observed in the π ^+ f_0(980) final state in the π ^-p→ π ^+π ^-π ^- p process. Available theoretical explanations include tetraquark or rescattering effects due to a_1(1260) decays. If the a_1(1420) were induced by the rescattering, its production rates are completely determined by those of the a_1(1260). Our numerical results for decays into the a_1(1260) indicate that there is a promising prospect to study these decays on experiments including BES-III, LHCb, Babar, Belle, and CLEO-c, the forthcoming Super-KEKB factory and the under-design Circular Electron-Positron Collider.

  15. Monolithic hybrid mode-locked 1. 3. mu. m semiconductor lasers

    SciTech Connect

    Morton, P.A.; Bowers, J.E. ); Koszi, L.A.; Soler, M.; Lopata, J.; Wilt, D.P. )

    1990-01-08

    We describe the first results of hybrid mode locking combining both active and passive mode locking of a semiconductor laser. These functions are integrated into a monolithic device with a 1.3 {mu}m GaInAsP gain region, an active waveguide, and a saturable absorber. The devices have low threshold currents, and exhibit hysteresis in their light/current characteristics. The long integrated waveguides allow mode locking at a repetition rate of 15 GHz without the need for an external cavity. Pulse widths as short as 1.4 ps have been demonstrated using the combined effects of active and passive mode locking.

  16. Segregative clustering of Lo and Ld membrane microdomains induced by local pH gradients in GM1-containing giant vesicles: a lipid model for cellular polarization.

    PubMed

    Staneva, Galya; Puff, Nicolas; Seigneuret, Michel; Conjeaud, Hélène; Angelova, Miglena I

    2012-11-27

    Several cell polarization processes are coupled to local pH gradients at the membrane surface. We have investigated the involvement of a lipid-mediated effect in such coupling. The influence of lateral pH gradients along the membrane surface on lipid microdomain dynamics in giant unilamellar vesicles containing phosphatidylcholine, sphingomyelin, cholesterol, and the ganglioside GM1 was studied. Lo/Ld phase separation was generated by photosensitization. A lateral pH gradient was established along the external membrane surface by acid local microinjection. The gradient promotes the segregation of microdomains: Lo domains within an Ld phase move toward the higher pH side, whereas Ld domains within an Lo phase move toward the lower pH side. This results in a polarization of the vesicle membrane into Lo and Ld phases poles in the axis of the proton source. A secondary effect is inward tubulation in the Ld phase. None of these processes occurs without GM1 or with the analog asialo-GM1. These are therefore related to the acidic character of the GM1 headgroup. LAURDAN fluorescence experiments on large unilamellar vesicles indicated that, with GM1, an increase in lipid packing occurs with decreasing pH, attributed to the lowering of repulsion between GM1 molecules. Packing increase is much higher for Ld phase vesicles than for Lo phase vesicles. It is proposed that the driving forces for domain vectorial segregative clustering and vesicle polarization are related to such differences in packing variations with pH decrease between the Lo and Ld phases. Such pH-driven domain clustering might play a role in cellular membrane polarization processes in which local lateral pH gradients are known to be important, such as migrating cells and epithelial cells. PMID:23121205

  17. Subharmonic Fourier domain mode locking.

    PubMed

    Eigenwillig, Christoph M; Wieser, Wolfgang; Biedermann, Benjamin R; Huber, Robert

    2009-03-15

    We demonstrate a subharmonically Fourier domain mode-locked wavelength-swept laser source with a substantially reduced cavity fiber length. In contrast to a standard Fourier domain mode-locked configuration, light is recirculated repetitively in the delay line with the optical bandpass filter used as switch. The laser has a fundamental optical round trip frequency of 285 kHz and can be operated at integer fractions thereof (subharmonics). Sweep ranges up to 95 nm full width centred at 1317 nm are achieved at the 1/5th subharmonic. A maximum sensitivity of 116 dB and an axial resolution of 12 microm in air are measured at an average sweep power of 12 mW. A sensitivity roll-off of 11 dB over 4 mm and 25 dB over 10 mm is observed and optical coherence tomography imaging is demonstrated. Besides the advantage of a reduced fiber length, subharmonic Fourier domain mode locking (shFDML) enables simple scaling of the sweep speed by extracting light from the delay part of the resonator. A sweep rate of 570 kHz is achieved. Characteristic features of shFDML operation, such as power leakage during fly-back and cw breakthrough, are investigated. PMID:19282912

  18. Two modes for dune orientation

    NASA Astrophysics Data System (ADS)

    Courrech Du Pont, Sylvain; Narteau, Clément; Gao, Xin

    2015-11-01

    Earth sand seas experience winds that blow with different strengths and from different directions in line with the seasons. In response, dune fields show a rich variety of shapes from small crescentic barchans to big star and linear dunes. Linear dunes often exhibit complex and compound patterns with different length scales and orientations, which seem difficult to relate to a single wind cycle. We present results of underwater experiments and numerical simulations where a single wind regime can lead to two different dunes orientation depending on sediment availability. Sediment availability selects the overriding mechanism for the formation of dunes: increasing in height from the destabilization of a sand bed or elongating in a finger on a non-erodible ground from a localized sand source. These mechanisms drive the dunes orientation. Therefore, dunes alignment maximizes dunes orthogonality to sand fluxes in the bed instability mode, while dunes are aligned with the sand transport direction in the fingering mode. Then, we derive a model for dunes orientation, which explains the coexistence of bedforms with different alignments and quantitatively predicts the orientation of dunes in Earth deserts. Finally, we explore the phase diagram and the stability of the fingering mode.

  19. Mode pumping experiments on biomolecules

    SciTech Connect

    Austin, R.H.; Erramilli, S.; Xie, A.; Schramm, A.

    1995-12-31

    We will explore several aspects of protein dynamics and energy transfer that can be explored by using the intense, picosecond, tunable mid-IR output of the FEL. In order of appearance they are: (1) Saturation recovery and inter-level coupling of the low temperature amide-I band in acetanilide. This is a continuation of earlier experiments to test soliton models in crystalline hydrogen bonded solids. In this experiment we utilize the sub-picosecond time resolution and low repetition rate of the Stanford SCLA FEL to do both T{sub 1} and T{sub 2} relaxation measurements at 1650 cm{sup -1}. (2) Probing the influence of collective dynamics in sensory rhodopsin. In this experiment we use the FIR output of the Stanford FIREFLY FEL to determine the lifetime of collective modes in the photo-active protein sensory rhodopsin, and begin experiments on the influence of collective modes on retinal reaction dynamics. (3) Probing the transition states of enzymes. This experiment, in the initial stages, attempts to use the intense IR output of the FEL to probe and influence the reaction path of a transition state analog for the protein nucleoside hydrolase. The transition state of the inosine substrate is believed to have critical modes softened by the protein so that bond-breaking paths show absorption at approximately 800 cm{sup -1}. A form of action spectrum using FEL excitation will be used to probe this state.

  20. Mixed-Mode-Bending Delamination Apparatus

    NASA Technical Reports Server (NTRS)

    Crews, John H., Jr.; Reeder, James R.

    1991-01-01

    Mixed-mode-bending delamination apparatus generates two types of delamination stress simultaneously in specimen from single externally applied point load. In technique, indivial mode I and mode II contributions to delamination in specimen analyzed by use of simple beam-theory equations, eliminating need for time-consuming, difficult numerical analysis. Allows wider range of mode I/mode II ratios than possible with many other methods. Mixed-mode delamination testing of interest in all fields utilizing composite materials, used mostly in aerospace field, but also used in automobiles, lightweight armored military vehicles, boats, and sporting equipment. Useful in general lumber, plywood, and adhesive industries, as well.

  1. Influence of Energetic Ions on Tearing Modes

    SciTech Connect

    Cai Huishan; Wang Shaojie; Xu Yinfeng; Cao Jintao; Li Ding

    2011-02-18

    In contrast with the stability effects of trapped energetic ions on tearing modes, the effects of circulating energetic ions (CEI) on tearing modes depend on the toroidal circulating direction, and are closely related to the momentum of energetic ions. CEI provide an additional source or sink of momentum to affect tearing modes. For co-CEI, tearing modes can be stabilized if the momentum of energetic ions is large enough. On the other hand, the growth of tearing modes can be enhanced by counter-CEI. Further, a possibility to suppress the island growth of neoclassical tearing modes by co-CEI is pointed out.

  2. Mode- and wavelength-division multiplexed transmission using all-fiber mode multiplexer based on mode selective couplers.

    PubMed

    Chang, Sun Hyok; Chung, Hwan Seok; Ryf, Roland; Fontaine, Nicolas K; Han, Changyo; Park, Kyung Jun; Kim, Kwangjoon; Lee, Jyung Chan; Lee, Jong Hyun; Kim, Byoung Yoon; Kim, Young Kie

    2015-03-23

    We propose all-fiber mode multiplexer composed of two consecutive LP₁₁ mode selective couplers that allows for the multiplexing of LP₀₁ mode and two-fold degenerate LP₁₁ modes. We demonstrate WDM transmission of 32 wavelength channels with 100 GHz spacing, each carrying 3 modes of 120 Gb/s polarization division multiplexed quadrature phase shifted keying (PDM-QPSK) signal, over 560 km of few-mode fiber (FMF). Long distance transmission is achieved by 6×6 multiple-input multiple-output digital signal processing and modal differential group delay compensated link of FMF. The all-fiber mode multiplexer has considerable potential to be used in mode- and wavelength-division multiplexed transmission. PMID:25837061

  3. Delamination detection in composite laminates using dispersion change based on mode conversion of Lamb waves

    NASA Astrophysics Data System (ADS)

    Okabe, Yoji; Fujibayashi, Keiji; Shimazaki, Mamoru; Soejima, Hideki; Ogisu, Toshimichi

    2010-11-01

    A new ultrasonic propagation system has been constructed using macrofiber composite (MFC) actuators and fiber Bragg grating (FBG) sensors. The MFCs and FBGs can be integrated into composite laminates because of their small size and high fracture strain. The developed system can send and receive broadband Lamb waves. In this research, this system was used to detect delamination damage in composite laminates. First, the multiple modes of Lamb waves in a carbon-fiber-reinforced plastic (CFRP) quasi-isotropic laminate were identified by transmitting and receiving the symmetric and antisymmetric modes separately. Then, the mode conversions at both tips of a delamination were investigated through an experiment and a two-dimensional finite element analysis (FEA). A new delamination detection method was proposed on the basis of the mode conversions, and experiments were carried out on laminates with an artificial delamination. When antisymmetric modes were excited, the frequency dispersion of the received A1 mode changed, depending on the delamination length owing to the mode conversion between the A1 mode and the S0 mode. This phenomenon was confirmed through the FEA and these results prove that this new method is effective in detecting a delamination in CFRP laminates.

  4. The hydrogen bond network of water supports propagating optical phonon-like modes

    NASA Astrophysics Data System (ADS)

    Elton, Daniel; Fernadez-Serra, Marivi

    The local structure of liquid water as a function of temperature is a source of intense research. This structure is intimately linked to the dynamics of water molecules, which can be measured using Raman and infrared spectroscopies. Vibrational modes in liquids are usually considered to be associated to the motions of single molecules or small clusters. Previously, the librational Raman peaks of water were assigned to the librational motions of single molecules. By comparing experimental Raman and IR spectra we show these assignments are problematic. Using molecular dynamics simulations we study the k-dependent dielectric susceptibility of water. We find dispersive optical phonon-like modes in water's librational and OH stretching bands. We argue that on subpicosecond time scales these modes propagate through water's hydrogen bond network over distances of up to two nanometers. In the long wavelength limit these optical modes exhibit longitudinal-transverse splitting, indicating the presence of coherent long range dipole-dipole interactions. Studying how LO-TO splitting evolves with temperature may yield insight into how local structure changes. Our results indicate the dynamics of liquid water have more similarities to ice than previously thought. Reference: arXiv:1507.06363 This work was partially supported by DOE Award No. DE-FG02-09ER16052 (D.C.E.) and by DOE Early Career Award No. DE-SC0003871 (M.V.F.S.).

  5. "Good Vibrations": A workshop on oscillations and normal modes

    NASA Astrophysics Data System (ADS)

    Barbieri, Sara; Carpineti, Marina; Giliberti, Marco; Rigon, Enrico; Stellato, Marco; Tamborini, Marina

    2016-05-01

    We describe some theatrical strategies adopted in a two hour workshop in order to show some meaningful experiments and the underlying useful ideas to describe a secondary school path on oscillations, that develops from harmonic motion to normal modes of oscillations, and makes extensive use of video analysis, data logging, slow motions and applet simulations. Theatre is an extremely useful tool to stimulate motivation starting from positive emotions. That is the reason why the theatrical approach to the presentation of physical themes has been explored by the group "Lo spettacolo della Fisica" (http://spettacolo.fisica.unimi.it) of the Physics Department of University of Milano for the last ten years (Carpineti et al., JCOM, 10 (2011) 1; Nuovo Cimento B, 121 (2006) 901) and has been inserted also in the European FP7 Project TEMI (Teaching Enquiry with Mysteries Incorporated, see http://teachingmysteries.eu/en) which involves 13 different partners coming from 11 European countries, among which the Italian (Milan) group. According to the TEMI guidelines, this workshop has a written script based on emotionally engaging activities of presenting mysteries to be solved while participants have been involved in nice experiments following the developed path.

  6. Spectral Line Measurements in Exceptionally Low SNR Achieved by Virtue of the KLT (Karhunen-Loève Transform)

    NASA Astrophysics Data System (ADS)

    Maccone, C.; Pluchino, S.; Schillirò, F.

    2009-12-01

    A little-known tool for spectral line measurements is the KLT (Karhunen-Loève Transform). This mathematical algorithm is superior to the classical FFT in that: 1) The KLT can filter signals out of the background noise over both wide and narrow bands. On the contrary, the FFT rigorously applies to narrow-band signals only. 2) The KLT can be applied to random functions that are non-stationary in time, i.e. whose autocorrelation is a function of the two independent variables t1 and t2 separately. Again, this is a sheer advantage of the KLT over the FFT, since the FFT rigorously applies to stationary processes only, i.e. when the autocorrelation is a function of the absolute value of the difference of t1 and t2. 3) The KLT can detect signals embedded in noise to unbelievably small values of the Signal-to-Noise Ratio (SNR), like 10-3 or so. This particular feature of the KLT is described in detail in this paper.

  7. Karhunen-Loève treatment to remove noise and facilitate data analysis in sensing, spectroscopy and other applications.

    PubMed

    Zaharov, V V; Farahi, R H; Snyder, P J; Davison, B H; Passian, A

    2014-11-21

    Resolving weak spectral variations in the dynamic response of materials that are either dominated or excited by stochastic processes remains a challenge. Responses that are thermal in origin are particularly relevant examples due to the delocalized nature of heat. Despite its inherent properties in dealing with stochastic processes, the Karhunen-Loève expansion has not been fully exploited in measurement of systems that are driven solely by random forces or can exhibit large thermally driven random fluctuations. Here, we present experimental results and analysis of the archetypes (a) the resonant excitation and transient response of an atomic force microscope probe by the ambient random fluctuations and nanoscale photothermal sample response, and (b) the photothermally scattered photons in pump-probe spectroscopy. In each case, the dynamic process is represented as an infinite series with random coefficients to obtain pertinent frequency shifts and spectral peaks and demonstrate spectral enhancement for a set of compounds including the spectrally complex biomass. The considered cases find important applications in nanoscale material characterization, biosensing, and spectral identification of biological and chemical agents. PMID:25252650

  8. Local coupling (LoCo) vs. large-scale coupled (LsCo) land-atmosphere interactions in idealized experiments

    NASA Astrophysics Data System (ADS)

    Gentine, P.; Lintner, B. R.; Findell, K. L.; Rochetin, N.; Sobel, A. H.; Anber, U. M.

    2014-12-01

    We will present two idealized epxeriments/methodologies to investigate local (LoCo) and large-scale (LsCo) coupling between the surface and the atmsophere: the contiental Radiative-Convective Equilibrium (RCE) and the continental Weak Temperature Gradient (WTG). The RCE defines an equilibrium state of coupling between the surafce and the atmosphere isolated from any large-scale dependence, which were investigated within the single column model of the Laboratoire de Meteorologie Dynamique (LMD) coupled to a simple bucket land model. This studies emphasizes the role of low-level cloud and the diurnal cylce of the boundary layer on the final state of the system. In the WTG we investigate the coupling between the surface and the atmosphere during the dry and wet season of the Amazon with the WRF model coupled to the NOAH land-surface model. Large-scale coupling is obtained with the WTG. The dry and wet season demonstrate very fundamental behavior: in the dry season deep convection is generated by radiative cooling in the higher troposhere and is disconnected from the surface. In the wet season the coupling between the surface and the atmosphere is much tighter. We suggest that the WTG is a powerful tool to investigate the coupling between the surface and the atmosphere, which solves two major issues: the limited resolution of convection in GCMs and the lack of large-scale coupling in CRM. Later investigation will look at the effect of deforestation, water table and distance from the ocean.

  9. Rotation and conversion of transmission mode based on a rotatable elliptical core ring resonator

    NASA Astrophysics Data System (ADS)

    Liu, Bin; Liu, Yun-Feng; Li, Shu-Jing; He, Xing-Dao

    2016-06-01

    A compact plasmonic waveguide system consisting of a rotating elliptical core ring (ECR) coupled two metal-insulator-metal (MIM) waveguides is proposed. Influences of the eccentricity and rotation angle of the elliptical core on the transmission characteristics are studied in detail, by using Finite-Difference Time-Domain (FDTD) method. Compared with circular core in ring resonator, the elliptical core will lead to the asymmetric field distributions of intrinsic mode. Based on this, a 1×2 splitter is designed, in which the beam-splitting ratio can be adjusted by changing the eccentricity of the elliptical core. In addition, we find that the intrinsic mode of ECR rotate with elliptical core and gradually convert to its orthogonal mode. Separation of the pair orthogonal modes increases with growth of the eccentricity of the elliptical core. And, the higher order intrinsic mode corresponds to the shorter rotation angle of mode conversion.

  10. Reflectionless compact plasmonic waveguide mode converter by using a mode-selective cavity.

    PubMed

    Kim, Joonsoo; Lee, Seung-Yeol; Park, Hyeonsoo; Lee, Kyookeun; Lee, Byoungho

    2015-04-01

    A compact transmissive plasmonic waveguide mode converter which aims for the elimination of reflection and transmission of unconverted mode is proposed. The proposed scheme exploits a cavity formed by mode selective mirrors, which only allows two output modes: the transmission of the target mode and the reflection of the input mode. By appropriately tuning cavity lengths, the reflection of the input mode can also be suppressed to near zero by destructive interference, thereby all the residual outgoing modes are suppressed. The proposed device might be useful in the design of integrated photonic system since it relaxes the problem of unwanted reflection. PMID:25968736

  11. LoCuSS: comparison of observed X-ray and lensing galaxy cluster scaling relations with simulations (Corrigendum)

    NASA Astrophysics Data System (ADS)

    Zhang, Y.-Y.; Finoguenov, A.; Böhringer, H.; Kneib, J.-P.; Smith, G. P.; Kneissl, R.; Okabe, N.; Dahle, H.

    2011-03-01

    The article by Zhang et al. (2008, A&A, 482, 451) contains an error in Table A.1 in online material (p. 3). In preparing the final version of Table A.1, we inadvertently used the wrong conversion from degree to hh:mm:ss, with the result that the cluster coordinates were not correctly tabulated in Table A.1. We note that this does not affect any results in Zhang et al. (2008). Nevertheless, we regret this error and provide the actual cluster coordinates used in our analysis in Table A.1 in the following page.

  12. Energetic Particle-induced Geodesic Acoustic Mode

    SciTech Connect

    Fu, G.Y.

    2008-09-12

    A new energetic particle-induced Geodesic Acoustic Mode (EGAM) is shown to exist. The mode frequency, mode structure, and mode destabilization are determined non-perturbatively by energetic particle kinetic effects. In particular the EGAM frequency is found to be substantially lower than the standard GAM frequency. The radial mode width is determined by the energetic particle drift orbit width and can be fairly large for high energetic particle pressure and large safety factor. These results are consistent with the recent experimental observation of the beam- driven n=0 mode in DIII-D. The new mode is important since it can degrade energetic particle confinement as shown in the DIII-D experiments. The new mode may also affect the thermal plasma confinement via its interaction with plasma micro-turbulence.

  13. Waveguide mode converter and method using same

    DOEpatents

    Moeller, Charles P.

    1990-01-01

    A waveguide mode converter converts electromagnetic power being transmitted in a TE.sub.0n or a TM.sub.0n mode, where n is an integer, to an HE.sub.11 mode. The conversion process occurs in a single stage without requiring the power to pass through any intermediate modes. The converter comprises a length of circular corrugated waveguide formed in a multiperiod periodic curve. The period of the curve is selected to couple the desired modes and decouple undesired modes. The corrugation depth is selected to control the phase propagation constant, or wavenumbers, of the input and output modes, thereby preventing coherent coupling to competing modes. In one embodiment, both the period and amplitude of the curve may be selectively adjusted, thereby allowing the converter to be tuned to maximize the conversion efficiency.

  14. Identifying predictors of survey mode preference.

    PubMed

    Smyth, Jolene D; Olson, Kristen; Millar, Morgan M

    2014-11-01

    To increase the likelihood of response, many survey organizations attempt to provide sample members with a mode they are thought to prefer. Mode assignment is typically based on conventional wisdom or results from mode choice studies that presented only limited options. In this paper we draw heavily on research and theory from the mode effects and the survey participation literatures to develop a framework for understanding what characteristics should predict mode preferences. We then test these characteristics using data from two different surveys. We find that measures of familiarity with and access to a mode are the strongest predictors of mode preference and measures of safety concerns, physical abilities, and normative concerns are unexpectedly weak predictors. Our findings suggest that variables that may exist on sample frames can be used to inform the assignment of "preferred" modes to sample members. PMID:25131280

  15. Path planning during combustion mode switch

    SciTech Connect

    Jiang, Li; Ravi, Nikhil

    2015-12-29

    Systems and methods are provided for transitioning between a first combustion mode and a second combustion mode in an internal combustion engine. A current operating point of the engine is identified and a target operating point for the internal combustion engine in the second combustion mode is also determined. A predefined optimized transition operating point is selected from memory. While operating in the first combustion mode, one or more engine actuator settings are adjusted to cause the operating point of the internal combustion engine to approach the selected optimized transition operating point. When the engine is operating at the selected optimized transition operating point, the combustion mode is switched from the first combustion mode to the second combustion mode. While operating in the second combustion mode, one or more engine actuator settings are adjusted to cause the operating point of the internal combustion to approach the target operating point.

  16. Experimental investigation on flow modes of electrospinning

    NASA Astrophysics Data System (ADS)

    Si, Ting; Li, Guang-Bin; Chen, Xing-Xing; Tian, Rui-Jun; Yin, Xie-Zhen

    2012-06-01

    Electrospinning experiments are performed by using a set of experimental apparatus, a stroboscopic system is adopted for capturing instantaneous images of the conejet configuration. The cone and the jet of aqueous solutions of polyethylene oxide (PEO) are formed from an orifice of a capillary tube under the electric field. The viscoelastic constitutive relationship of the PEO solution is measured and discussed. The phenomena owing to the jet instability are described, five flow modes and corresponding structures are obtained with variations of the fluid flow rate Q, the electric potential U and the distance h from the orifice of the capillary tube to the collector. The flow modes of the cone-jet configuration involves the steady bending mode, the rotating bending mode, the swinging rotating mode, the blurring bending mode and the branching mode. Regimes in the Q-U plane of the flow modes are also obtained. These results may provide the fundamentals to predict the operating conditions expected in practical applications.

  17. Tissue lesion created by HIFU in continuous scanning mode

    NASA Astrophysics Data System (ADS)

    Fan, Tingbo; Liu, Zhenbo; Zhang, Dong

    2012-09-01

    The lesion formation was numerically and experimentally investigated by the continuous scanning mode. Simulations were presented based on the combination of Khokhlov-Zabolotskaya-Kuznetov (KZK) equation and bio-heat equation. Measurements were performed on porcine liver tissues using a 1.01 MHz single-element focused transducer at various acoustic powers, confirmed the predicted results. Controlling of the peak temperature and lesion by the scanning speed may be exploited for improvement of efficiency in HIFU therapy.

  18. Optical waveguides having flattened high order modes

    DOEpatents

    Messerly, Michael Joseph; Beach, Raymond John; Heebner, John Edward; Dawson, Jay Walter; Pax, Paul Henry

    2014-08-05

    A deterministic methodology is provided for designing optical fibers that support field-flattened, ring-like higher order modes. The effective and group indices of its modes can be tuned by adjusting the widths of the guide's field-flattened layers or the average index of certain groups of layers. The approach outlined here provides a path to designing fibers that simultaneously have large mode areas and large separations between the propagation constants of its modes.

  19. Multiple mode model of tokamak transport

    SciTech Connect

    Singer, C.E.; Ghanem, E.S.; Bateman, G.; Stotler, D.P.

    1989-07-01

    Theoretical models for radical transport of energy and particles in tokamaks due to drift waves, rippling modes, and resistive ballooning modes have been combined in a predictive transport code. The resulting unified model has been used to simulate low confinement mode (L-mode) energy confinement scalings. Dependence of global energy confinement on electron density for the resulting model is also described. 26 refs., 1 fig., 2 tabs.

  20. Normal modes and continuous spectra

    SciTech Connect

    Balmforth, N.J.; Morrison, P.J.

    1994-12-01

    The authors consider stability problems arising in fluids, plasmas and stellar systems that contain singularities resulting from wave-mean flow or wave-particle resonances. Such resonances lead to singularities in the differential equations determining the normal modes at the so-called critical points or layers. The locations of the singularities are determined by the eigenvalue of the problem, and as a result, the spectrum of eigenvalues forms a continuum. They outline a method to construct the singular eigenfunctions comprising the continuum for a variety of problems.

  1. Squint mode SAR processing algorithms

    NASA Technical Reports Server (NTRS)

    Chang, C. Y.; Jin, M.; Curlander, J. C.

    1989-01-01

    The unique characteristics of a spaceborne SAR (synthetic aperture radar) operating in a squint mode include large range walk and large variation in the Doppler centroid as a function of range. A pointing control technique to reduce the Doppler drift and a new processing algorithm to accommodate large range walk are presented. Simulations of the new algorithm for squint angles up to 20 deg and look angles up to 44 deg for the Earth Observing System (Eos) L-band SAR configuration demonstrate that it is capable of maintaining the resolution broadening within 20 percent and the ISLR within a fraction of a decibel of the theoretical value.

  2. Passive mitigation of mode instabilities

    NASA Astrophysics Data System (ADS)

    Jauregui, C.; Otto, H.-J.; Stutzki, F.; Jansen, F.; Limpert, J.; Tünnermann, A.

    2014-03-01

    The phenomenon of mode instabilities has quickly become the most limiting effect for a further scaling of the average power of fiber laser systems. Consequently it is of great importance to find solutions for this problem. In this work we propose two concrete possible passive mitigation strategies: the first one is based on the reduction of the heat load in the fiber, whereas the second one is based on the reduction of the pump absorption. In both cases a significant increase of the threshold is expected.

  3. Fracture - An Unforgiving Failure Mode

    NASA Technical Reports Server (NTRS)

    Goodin, James Ronald

    2006-01-01

    During the 2005 Conference for the Advancement for Space Safety, after a typical presentation of safety tools, a Russian in the audience simply asked, "How does that affect the hardware?" Having participated in several International System Safety Conferences, I recalled that most attention is dedicated to safety tools and little, if any, to hardware. The intent of this paper on the hazard of fracture and failure modes associated with fracture is my attempt to draw attention to the grass roots of system safety - improving hardware robustness and resilience.

  4. A TE01 mode generator for testing high power transmission devices.

    PubMed

    Wu, Zewei; Li, Hao; Fu, Hua; Li, Tianming; Xu, Jianhua

    2013-11-01

    To verify the performance of high power waveguide transmission devices such as the miter bend, the waveguide taper, and the quasi-optical mode converter by the low power measurement, a TE01 mode generator, converts the rectangular waveguide TE10 mode into the cylindrical waveguide TE01 mode, for Ka-band is designed, fabricated, and measured. The proposed generator consists of a TE10 to TE20 rectangular waveguide mode converter and a rectangular TE20 to circular TE01 mode converter. The converting process in each section is analyzed and the working principles are discussed. Two prototypes are built and tested. The back-to-back transmission measured results agree well with the numerical calculations. The measured optimum transmissions are 97% with a 1-dB bandwidth from 29.2 GHz to 31.6 GHz. The angle-independent transmissions demonstrate high mode purity and the presence of TE01 mode confirmed by the far-field measurement. The proposed mode generator features high conversion efficiency, high mode purity, and moderate broad bandwidth. PMID:24289420

  5. The Design of the Low Frequency All Sky Monitor (LoFASM) for the Study of Radio Transients and Student Training

    NASA Astrophysics Data System (ADS)

    Jenet, Fredrick; Cohen, S.; Dartez, L. P.; Ford, A.; Garcia, A.; Hinojosa, J.; Longoria, C.; Lunsford, G.; Mata, A.; Miller, R. B.; Reser, J.; Rivera, J.; Stovall, K.; Creighton, T. D.; Hicks, B.; Price, R. H.; Taylor, G. B.

    2013-01-01

    The Astronomy and Astrophysics Decadal Survey (Astro2010) identified transient science and time-domain studies as one of the most promising discovery areas of the coming decade. The Low Frequency All Sky Monitor (LoFASM) is a new distributed radio array designed specifically to search for and to study transient radio phenomena in the 5-88 MHz frequency range. LoFASM consists of four stations, each made up of 12 cross dipole-antennas. The stations were constructed by undergraduates at the University of Texas at Brownsville's Center for Advanced Radio Astronomy. LoFASM utilizes the same antennas and front-end electronics developed for the Long Wavelength Array (LWA) project by the Naval Research Laboratory. The stations are located at Port Mansfield, Texas, the LWA North Arm site of the LWA1 Radio Observatory in New Mexico, the Green Bank Radio Observatory, West Virginia, and NASA's Goldstone tracking center in California. Having the stations in these geographically distinct regions allows for the immediate discrimination between bonafide astronomical transient events and radio frequency interference. In this presentation, we will give an overview of LoFASM's design and capabilities as well as the project's primary scientific objectives

  6. Representations of Mexican American Migrant Childhood in Rivera's "...y no se lo trago la tierra" and Viramontes's "Under the Feet of Jesus"

    ERIC Educational Resources Information Center

    Beck, Scott A.; Rangel, Dolores E.

    2009-01-01

    This article gives an analysis of two books: Thomas Rivera's "...y no se lo trago la tierra" and Helena Maria Viramontes's "Under the Feet of Jesus". The two books are strong and important literary texts that stand in close relation to each other. Both texts treat the subject of migrant childhood by affirming central themes of Chicano literature.…

  7. 76 FR 50152 - Airworthiness Directives; Lycoming Engines (L)O-360, (L)IO-360, AEIO-360, O-540, IO-540, AEIO-540...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-12

    ...-14778 (71 FR 57407, September 29, 2006), for Lycoming Engines (L)O-360, (L)IO-360, AEIO-360, O-540, IO... 12866, (2) Is not a ``significant rule'' under the DOT Regulatory Policies and Procedures (44 FR 11034...-09, Amendment 39-14778 (71 FR 57407, September 29, 2006), and adding the following new AD:...

  8. TUTOR User's Memo Using AUTHOR MODE.

    ERIC Educational Resources Information Center

    Avner, R. A.

    While a PLATO station is normally used to present lessons (STUDENT MODE), a station can also be used by a teacher to produce or alter lessons or to control lesson presentation (AUTHOR MODE). This memo describes the manner in which student records and lesson material are stored in the computer memory, prescribes the method of entry to AUTHOR MODE,…

  9. Extracting coherent modes from partially coherent wavefields

    SciTech Connect

    Flewett, Samuel; Quiney, Harry M.; Tran, Chanh Q.; Nugent, Keith A.

    2009-09-08

    A method for numerically recovering the coherent modes and their occupancies from a known mutual optical intensity function is described. As an example, the technique is applied to previously published experimental data from an x-ray undulator source. The data are found to be described by three coherent modes, and the functional forms and relative occupancies of these modes are recovered.

  10. Family Mode Deactivation Therapy Results and Implications

    ERIC Educational Resources Information Center

    Apsche, Jack A.; Bass, Christopher K.

    2006-01-01

    This article highlights the inclusion of Mode Deactivation Therapy as a treatment modality for families in crisis. As an empirically validated treatment, Mode Deactivation Therapy has been effective in treating a wide variety of psychological issues. Mode Deactivation Therapy, (MDT) was developed to treat adolescents with disorders of conduct…

  11. Mode of action of etoxazole.

    PubMed

    Nauen, Ralf; Smagghe, Guy

    2006-05-01

    The mode of action of the 2,4-diphenyl-1,3-oxazoline acaricide/insecticide etoxazole has been argued to be moulting inhibition, but experimental results supporting this hypothesis are lacking. This study investigated the effect of etoxazole on chitin biosynthesis in the fall armyworm, Spodoptera frugiperda (Smith) (Lepidoptera: Noctuidae). Etoxazole induced moulting defects in fall armyworm larvae similar, if not identical, to those caused by benzoylphenylureas, a well-known class of insecticidal chitin biosynthesis inhibitors. Furthermore, in contrast to untreated larvae, the chitin content in the integuments of larvae several days after treatment did not differ from that in freshly ecdysed individuals, thus suggesting strong chitin biosynthesis inhibition in vivo. A more detailed investigation of the inhibitory potential by incubating cultured integument pieces from larvae of S. frugiperda with [14C]N-acetyl-D-glucosamine, a radiolabelled chitin precursor, revealed I50 values of 2.95 and 0.071 microM for etoxazole and triflumuron respectively. The incorporation of radiolabel into potassium hydroxide-resistant material was inhibited by etoxazole in a dose-dependent manner. Based on these results, it is concluded that the acaricidal and insecticidal mode of action of etoxazole is chitin biosynthesis inhibition. PMID:16555232

  12. Micromechanics of nonlinear plastic modes

    NASA Astrophysics Data System (ADS)

    Lerner, Edan

    2016-05-01

    Nonlinear plastic modes (NPMs) are collective displacements that are indicative of imminent plastic instabilities in elastic solids. In this work we formulate the atomistic theory that describes the reversible evolution of NPMs and their associated stiffnesses under external deformations. The deformation dynamics of NPMs is compared to those of the analogous observables derived from atomistic linear elastic theory, namely, destabilizing eigenmodes of the dynamical matrix and their associated eigenvalues. The key result we present and explain is that the dynamics of NPMs and of destabilizing eigenmodes under external deformations follow different scaling laws with respect to the proximity to imminent instabilities. In particular, destabilizing modes vary with a singular rate, whereas NPMs exhibit no such singularity. As a result, NPMs converge much earlier than destabilizing eigenmodes to their common final form at plastic instabilities. This dynamical difference between NPMs and linear destabilizing eigenmodes underlines the usefulness of NPMs for predicting the locus and geometry of plastic instabilities, compared to their linear-elastic counterparts.

  13. Principal elementary mode analysis (PEMA).

    PubMed

    Folch-Fortuny, Abel; Marques, Rodolfo; Isidro, Inês A; Oliveira, Rui; Ferrer, Alberto

    2016-03-01

    Principal component analysis (PCA) has been widely applied in fluxomics to compress data into a few latent structures in order to simplify the identification of metabolic patterns. These latent structures lack a direct biological interpretation due to the intrinsic constraints associated with a PCA model. Here we introduce a new method that significantly improves the interpretability of the principal components with a direct link to metabolic pathways. This method, called principal elementary mode analysis (PEMA), establishes a bridge between a PCA-like model, aimed at explaining the maximum variance in flux data, and the set of elementary modes (EMs) of a metabolic network. It provides an easy way to identify metabolic patterns in large fluxomics datasets in terms of the simplest pathways of the organism metabolism. The results using a real metabolic model of Escherichia coli show the ability of PEMA to identify the EMs that generated the different simulated flux distributions. Actual flux data of E. coli and Pichia pastoris cultures confirm the results observed in the simulated study, providing a biologically meaningful model to explain flux data of both organisms in terms of the EM activation. The PEMA toolbox is freely available for non-commercial purposes on http://mseg.webs.upv.es. PMID:26905301

  14. Split-mode ultrasonic transducer.

    PubMed

    Ostrovskii, Igor; Cremaldi, Lucien

    2013-08-01

    A split-mode ultrasonic transducer is investigated in both theory and experiment. This transducer is a two-dimensional structure of periodically poled domains in a ferroelectric wafer with free surfaces. The acoustic vibrations are excited by a radio frequency electric current applied along the length of the wafer, which allows the basal-plane surfaces to be free of metal coatings and thus ready for further biomedical applications. A specific physical property of this transducer consists of the multiple acousto-electric resonances, which occur due to an acoustic mode split when the acoustic half-wavelength is equal to the domain length. Possible applications include ultrasonic generation and detection at the micro-scale, intravascular sonification and visualization, ultrasound therapy of localized small areas such as the eye, biomedical applications for cell cultures, and traditional nondestructive testing including bones and tissues. A potential use of a non-metallized wafer is a therapeutic application with double action that is both ultrasound itself and an electric field over the wafer. The experimental measurements and theoretical calculations are in good agreement. PMID:23927212

  15. Whispering Gallery Mode Optomechanical Resonator

    NASA Technical Reports Server (NTRS)

    Aveline, David C.; Strekalov, Dmitry V.; Yu, Nan; Yee, Karl Y.

    2012-01-01

    Great progress has been made in both micromechanical resonators and micro-optical resonators over the past decade, and a new field has recently emerged combining these mechanical and optical systems. In such optomechanical systems, the two resonators are strongly coupled with one influencing the other, and their interaction can yield detectable optical signals that are highly sensitive to the mechanical motion. A particularly high-Q optical system is the whispering gallery mode (WGM) resonator, which has many applications ranging from stable oscillators to inertial sensor devices. There is, however, limited coupling between the optical mode and the resonator s external environment. In order to overcome this limitation, a novel type of optomechanical sensor has been developed, offering great potential for measurements of displacement, acceleration, and mass sensitivity. The proposed hybrid device combines the advantages of all-solid optical WGM resonators with high-quality micro-machined cantilevers. For direct access to the WGM inside the resonator, the idea is to radially cut precise gaps into the perimeter, fabricating a mechanical resonator within the WGM. Also, a strategy to reduce losses has been developed with optimized design of the cantilever geometry and positions of gap surfaces.

  16. Untangled modes in multimode waveguides

    NASA Astrophysics Data System (ADS)

    Plöschner, Martin; Tyc, TomáÅ.¡; Čižmár, TomáÅ.¡

    2016-03-01

    Small, fibre-based endoscopes have already improved our ability to image deep within the human body. A novel approach introduced recently utilised disordered light within a standard multimode optical fibre for lensless imaging. Importantly, this approach brought very significant reduction of the instruments footprint to dimensions below 100 μm. The most important limitations of this exciting technology is the lack of bending flexibility - imaging is only possible as long as the fibre remains stationary. The only route to allow flexibility of such endoscopes is in trading-in all the knowledge about the optical system we have, particularly the cylindrical symmetry of refractive index distribution. In perfect straight step-index cylindrical waveguides we can find optical modes that do not change their spatial distribution as they propagate through. In this paper we present a theoretical background that provides description of such modes in more realistic model of real-life step-index multimode fibre taking into account common deviations in distribution of the refractive index from its ideal step-index profile. Separately, we discuss how to include the influence of fibre bending.

  17. A1C Test and Diabetes

    MedlinePlus

    ... laboratory tests. How does the A1C relate to estimated average glucose? Estimated average glucose (eAG) is calculated from the A1C. ... levels have the A1C test twice a year. Estimated average glucose (eAG) is calculated from the A1C ...

  18. Establishing an Appropriate Level of Detail (LoD) for a Building Information Model (BIM) - West Block, Parliament Hill, Ottawa, Canada

    NASA Astrophysics Data System (ADS)

    Fai, S.; Rafeiro, J.

    2014-05-01

    In 2011, Public Works and Government Services Canada (PWGSC) embarked on a comprehensive rehabilitation of the historically significant West Block of Canada's Parliament Hill. With over 17 thousand square meters of floor space, the West Block is one of the largest projects of its kind in the world. As part of the rehabilitation, PWGSC is working with the Carleton Immersive Media Studio (CIMS) to develop a building information model (BIM) that can serve as maintenance and life-cycle management tool once construction is completed. The scale and complexity of the model have presented many challenges. One of these challenges is determining appropriate levels of detail (LoD). While still a matter of debate in the development of international BIM standards, LoD is further complicated in the context of heritage buildings because we must reconcile the LoD of the BIM with that used in the documentation process (terrestrial laser scan and photogrammetric survey data). In this paper, we will discuss our work to date on establishing appropriate LoD within the West Block BIM that will best serve the end use. To facilitate this, we have developed a single parametric model for gothic pointed arches that can be used for over seventy-five unique window types present in the West Block. Using the AEC (CAN) BIM as a reference, we have developed a workflow to test each of these window types at three distinct levels of detail. We have found that the parametric Gothic arch significantly reduces the amount of time necessary to develop scenarios to test appropriate LoD.

  19. Broadband mode conversion via gradient index metamaterials

    PubMed Central

    Wang, HaiXiao; Xu, YaDong; Genevet, Patrice; Jiang, Jian-Hua; Chen, HuanYang

    2016-01-01

    We propose a design for broadband waveguide mode conversion based on gradient index metamaterials (GIMs). Numerical simulations demonstrate that the zeroth order of transverse magnetic mode or the first order of transverse electric mode (TM0/TE1) can be converted into the first order of transverse magnetic mode or the second order of transverse electric mode (TM1/TE2) for a broadband of frequencies. As an application, an asymmetric propagation is achieved by integrating zero index metamaterials inside the GIM waveguide. PMID:27098456

  20. Broadband mode conversion via gradient index metamaterials.

    PubMed

    Wang, HaiXiao; Xu, YaDong; Genevet, Patrice; Jiang, Jian-Hua; Chen, HuanYang

    2016-01-01

    We propose a design for broadband waveguide mode conversion based on gradient index metamaterials (GIMs). Numerical simulations demonstrate that the zeroth order of transverse magnetic mode or the first order of transverse electric mode (TM0/TE1) can be converted into the first order of transverse magnetic mode or the second order of transverse electric mode (TM1/TE2) for a broadband of frequencies. As an application, an asymmetric propagation is achieved by integrating zero index metamaterials inside the GIM waveguide. PMID:27098456

  1. Quasicoherent modes on the COMPASS tokamak

    NASA Astrophysics Data System (ADS)

    Melnikov, A. V.; Markovic, T.; Eliseev, L. G.; Adámek, J.; Aftanas, M.; Bilkova, P.; Boehm, P.; Gryaznevich, M.; Imrisek, M.; Lysenko, S. E.; Medvedev, S. Y.; Panek, R.; Peterka, M.; Seidl, J.; Stefanikova, E.; Stockel, J.; Weinzettl, V.; the COMPASS Team

    2015-06-01

    Multiple quasicoherent electromagnetic modes with steady-state frequency and different nature and location were observed in the COMPASS tokamak (R = 0.56 m, = 0.2 m) at Bt = 1.14 T with Co-NBI (PNBI = 0.2-0.5 MW, Eb = 32 keV) at frequencies 5 kHz < f < 250 kHz. Modes were observed in both low and high confinement (L- and H-modes) plasmas. Lower frequency modes with f < 50 kHz were identified as low m tearing and kink MHD modes, while higher frequency modes with 50 kHz < f < 250 kHz were considered as having Alfvénic nature. Unexpectedly, such modes were only observed in the H-mode, both in neutral beam injector-assisted and Ohmic, so the mode driving force is not yet clear. Using the linear MHD code KINX, we initially identified the observed mode with a ballooning structure is as beta induced Alfvén eigenmode (BAE) with m, n < 5, while an antiballooning mode is initially identified as toroidal Alfvén eigenmode (TAE) with m, n < 9.

  2. Mode coupling in spin torque oscillators

    NASA Astrophysics Data System (ADS)

    Zhang, Steven S.-L.; Zhou, Yan; Li, Dong; Heinonen, Olle

    2016-09-01

    A number of recent experimental works have shown that the dynamics of a single spin torque oscillator can exhibit complex behavior that stems from interactions between two or more modes of the oscillator, such as observed mode-hopping or mode coexistence. There has been some initial work indicating how the theory for a single-mode (macro-spin) spin torque oscillator should be generalized to include several modes and the interactions between them. In the present work, we rigorously derive such a theory starting with the Landau-Lifshitz-Gilbert equation for magnetization dynamics by expanding up to third-order terms in deviation from equilibrium. Our results show how a linear mode coupling, which is necessary for observed mode-hopping to occur, arises through coupling to a magnon bath. The acquired temperature dependence of this coupling implies that the manifold of orbits and fixed points may shift with temperature.

  3. Double mode Cepheids in M31

    SciTech Connect

    Poleski, Radosław

    2013-12-01

    Until now, double mode Cepheids (or beat Cepheids) were known only in the Galaxy, the Magellanic Clouds, and M33. Curiously, none of the more than 2000 Cepheids in M31 was claimed to show two pulsation modes. We conducted a systematic search for double mode Cepheids in the archival data of M31 and discovered four such objects. We identify one of the stars as a first and second overtone pulsator even though its secondary period is subject to strong aliasing. Two stars pulsate in the fundamental mode and the first overtone. Their fundamental periods are 9.392 days and 9.163 days. This makes them the first candidates for fundamental mode and first overtone Cepheids, of which double mode pulsations are caused by the 2:1 resonance of the fundamental mode and the second overtone.

  4. Global Alfven modes: Theory and experiment

    SciTech Connect

    Turnbull, A.D.; Strait, E.J.; Heidbrink, W.W.; Chu, M.S.; Duong, H.H.; Greene, J.M.; Lao, L.L.; Taylor, T.S.; Thompson, S.J. )

    1993-07-01

    It is shown that the theoretical predictions and experimental observations of toroidicity-induced Alfven eigenmodes (TAE's) are now in good agreement, with particularly detailed agreement in the mode frequencies. Calculations of the driving and damping rates predict the importance of continuum damping for low toroidal mode numbers and this is confirmed experimentally. However, theoretical calculations in finite-[beta], shaped discharges predict the existence of other global Alfven modes, in particular the ellipticity-induced Alfven eigenmode (EAE) and a new mode, the beta-induced Alfven eigenmode (BAE). The BAE mode is calculated to be in or below the same frequency range as the TAE mode and may contribute to the experimental observations at high [beta]. Experimental evidence and complementary analyses are presented confirming the presence of the EAE mode at higher frequencies.

  5. Numerical evaluation of uniform beam modes.

    SciTech Connect

    Tang, Y.; Reactor Analysis and Engineering

    2003-12-01

    The equation for calculating the normal modes of a uniform beam under transverse free vibration involves the hyperbolic sine and cosine functions. These functions are exponential growing without bound. Tables for the natural frequencies and the corresponding normal modes are available for the numerical evaluation up to the 16th mode. For modes higher than the 16th, the accuracy of the numerical evaluation will be lost due to the round-off errors in the floating-point math imposed by the digital computers. Also, it is found that the functions of beam modes commonly presented in the structural dynamics books are not suitable for numerical evaluation. In this paper, these functions are rearranged and expressed in a different form. With these new equations, one can calculate the normal modes accurately up to at least the 100th mode. Mike's Arbitrary Precision Math, an arbitrary precision math library, is used in the paper to verify the accuracy.

  6. Adiabatically-tapered fiber mode multiplexers.

    PubMed

    Yerolatsitis, S; Gris-Sánchez, I; Birks, T A

    2014-01-13

    Simple all-fiber three-mode multiplexers were made by adiabatically merging three dissimilar single-mode cores into one multimode core. This was achieved by collapsing air holes in a photonic crystal fiber and (in a separate device) by fusing and tapering separate telecom fibers in a fluorine-doped silica capillary. In each case the LP01 mode and both LP11 modes were individually excited from three separate input cores, with losses below 0.3 and 0.7 dB respectively and mode purities exceeding 10 dB. Scaling to more modes is challenging, but would be assisted by using single-mode fibers with a smaller ratio of cladding to core diameter. PMID:24515021

  7. Mode-routed fiber-optic add-drop filter

    NASA Technical Reports Server (NTRS)

    Moslehi, Behzad (Inventor); Black, Richard James (Inventor); Shaw, Herbert John (Inventor)

    2000-01-01

    New elements mode-converting two-mode grating and mode-filtering two-mode coupler are disclosed and used as elements in a system for communications, add-drop filtering, and strain sensing. Methods of fabrication for these new two-mode gratings and mode-filtering two-mode couplers are also disclosed.

  8. New Edge Coherent Mode Providing Continuous Transport in Long-Pulse H-mode Plasmas

    NASA Astrophysics Data System (ADS)

    Wang, H. Q.; Xu, G. S.; Wan, B. N.; Ding, S. Y.; Guo, H. Y.; Shao, L. M.; Liu, S. C.; Xu, X. Q.; Wang, E.; Yan, N.; Naulin, V.; Nielsen, A. H.; Rasmussen, J. Juul; Candy, J.; Bravenec, R.; Sun, Y. W.; Shi, T. H.; Liang, Y. F.; Chen, R.; Zhang, W.; Wang, L.; Chen, L.; Zhao, N.; Li, Y. L.; Liu, Y. L.; Hu, G. H.; Gong, X. Z.

    2014-05-01

    An electrostatic coherent mode near the electron diamagnetic frequency (20-90 kHz) is observed in the steep-gradient pedestal region of long pulse H-mode plasmas in the Experimental Advanced Superconducting Tokamak, using a newly developed dual gas-puff-imaging system and diamond-coated reciprocating probes. The mode propagates in the electron diamagnetic direction in the plasma frame with poloidal wavelength of ˜8 cm. The mode drives a significant outflow of particles and heat as measured directly with the probes, thus greatly facilitating long pulse H-mode sustainment. This mode shows the nature of dissipative trapped electron mode, as evidenced by gyrokinetic turbulence simulations.

  9. DE-1 observations of ordinary mode and extraordinary mode auroral kilometric radiation

    NASA Technical Reports Server (NTRS)

    Mellott, M. M.; Calvert, W.; Huff, R. L.; Gurnett, D. A.; Shawhan, S. D.

    1984-01-01

    Observations of auroral kilometric radiation (AKR) made with the Dynamics Explorer (DE-1) indicate the presence of both ordinary and extraordinary wave modes. Although the two modes usually occur separately, they are sometimes observed together. When both modes are present, the ordinary-mode component tends to occur at lower frequencies and with lower amplitudes than those of the accompanying extraordinary-mode component. On the other hand, the local electron gyrofrequency is an absolute lower frequency cutoff for both modes. Ordinary mode intensities are proportional to extraordinary mode intensities but less by roughly a factor of 50. Extraordinary mode ray paths are generally confined to a cone within 50 degrees of the source magnetic field direction and ordinary mode emissions are typically observed outside of this cone. This behavior suggests that both components are produced within the same source region but are then refracted differently as they escape.

  10. Variable optical attenuator and dynamic mode group equalizer for few mode fibers.

    PubMed

    Blau, Miri; Weiss, Israel; Gerufi, Jonathan; Sinefeld, David; Bin-Nun, Moran; Lingle, Robert; Grüner-Nielsen, Lars; Marom, Dan M

    2014-12-15

    Variable optical attenuation (VOA) for three-mode fiber is experimentally presented, utilizing an amplitude spatial light modulator (SLM), achieving up to -28dB uniform attenuation for all modes. Using the ability to spatially vary the attenuation distribution with the SLM, we also achieve up to 10dB differential attenuation between the fiber's two supported mode group (LP₀₁ and LP₁₁). The spatially selective attenuation serves as the basis of a dynamic mode-group equalizer (DME), potentially gain-balancing mode dependent optical amplification. We extend the experimental three mode DME functionality with a performance analysis of a fiber supporting 6 spatial modes in four mode groups. The spatial modes' distribution and overlap limit the available dynamic range and performance of the DME in the higher mode count case. PMID:25606998

  11. Mirror Modes in the Heliosheath

    SciTech Connect

    Tsurutani, B. T.; Guarnieri, F. L.; Echer, E. E.; Lakhina, G. S.; Verkhoglyadova, O. P.

    2011-01-04

    Mirror mode (MM) structures are identified in the Voyager 1 heliosheath magnetic field data. Their characteristics are: (1) quasiperiodic structures with a typical scale size of {approx}57 {rho}{sub p}(proton gyroradii), (2) little or no angular changes across the structures ({approx}3 deg. longitude and {approx}3 deg. latitude), and (3) a lack of sharp boundaries at the magnetic dip edges. It is proposed that the pickup of interstellar neutrals in the upstream region of the termination shock (TS) is the likely cause of MM instability during intervals when the IMF is nearly orthogonal to the solar wind flow direction. Concomitant (quasiperpendicular) shock compression of the MM structures at the TS and additional injection of pickup ions (PUIs) throughout the heliosheath will enhance MM growth.

  12. Representation of Ideal Magnetohydrodynamic Modes

    SciTech Connect

    Roscoe B. White

    2013-01-15

    One of the most fundamental properties of ideal magnetohydrodynamics is the condition that plasma motion cannot change magnetic topology. The conventional representation of ideal magnetohydrodynamic modes by perturbing a toroidal equilibrium field through δ Β = ∇ X (xi X B) ensures that δ B • ∇ ψ = 0 at a resonance, with ψ labelling an equilibrium flux surface. Also useful for the analysis of guiding center orbits in a perturbed field is the representation δ Β = ∇ X αB. These two representations are equivalent, but the vanishing of δ B • ∇ψ at a resonance is necessary but not sufficient for the preservation of field line topology, and a indiscriminate use of either perturbation in fact destroys the original equilibrium flux topology. It is necessary to find the perturbed field to all orders in xi to conserve the original topology. The effect of using linearized perturbations on stability and growth rate calculations is discussed

  13. Filamentation as primitive growth mode?

    PubMed

    Bigan, Erwan; Steyaert, Jean-Marc; Douady, Stéphane

    2015-12-01

    Osmotic pressure influences cellular shape. In a growing cell, chemical reactions and dilution induce changes in osmolarity, which in turn influence the cellular shape. Using a protocell model relying upon random conservative chemical reaction networks with arbitrary stoichiometry, we find that when the membrane is so flexible that its shape adjusts itself quasi-instantaneously to balance the osmotic pressure, the protocell either grows filamentous or fails to grow. This behavior is consistent with a mathematical proof. This suggests that filamentation may be a primitive growth mode resulting from the simple physical property of balanced osmotic pressure. We also find that growth is favored if some chemical species are only present inside the protocell, but not in the outside growth medium. Such an insulation requires specific chemical schemes. Modern evolved cells such as E. coli meet these requirements through active transport mechanisms such as the phosphotransferase system. PMID:26718101

  14. Filamentation as primitive growth mode?

    NASA Astrophysics Data System (ADS)

    Bigan, Erwan; Steyaert, Jean-Marc; Douady, Stéphane

    2015-12-01

    Osmotic pressure influences cellular shape. In a growing cell, chemical reactions and dilution induce changes in osmolarity, which in turn influence the cellular shape. Using a protocell model relying upon random conservative chemical reaction networks with arbitrary stoichiometry, we find that when the membrane is so flexible that its shape adjusts itself quasi-instantaneously to balance the osmotic pressure, the protocell either grows filamentous or fails to grow. This behavior is consistent with a mathematical proof. This suggests that filamentation may be a primitive growth mode resulting from the simple physical property of balanced osmotic pressure. We also find that growth is favored if some chemical species are only present inside the protocell, but not in the outside growth medium. Such an insulation requires specific chemical schemes. Modern evolved cells such as E. coli meet these requirements through active transport mechanisms such as the phosphotransferase system.

  15. Dementia and the default mode.

    PubMed

    Beason-Held, L L

    2011-06-01

    Changes in regional activity levels and network connectivity occur across the lifespan within the default mode network (DMN) of resting brain function. Changes with age are noted in most components of the DMN, especially in medial frontal/anterior cingulate and posterior cingulate/precuneus regions. Individuals with age-related disease such as mild cognitive impairment (MCI) and Alzheimer's disease (AD) demonstrate additional default-related changes particularly in posterior cingulate/precuneus and hippocampal regions. As these regions are areas of known pathologic change in both normal aging and age-related disease, examining DMN activity may allow future studies to more fully assess the relationship between pathology and function in these regions. The ability to form this structure-function link could allow us to determine critical factors involved in the decline or preservation of function in the presence of age-related neuropathology. PMID:21222595

  16. [Fetal macrosomia: mode of delivery].

    PubMed

    Tatarova, S; Popov, I; Khristova, P

    2004-01-01

    This study was provided among 1847 deliveries from January, 1 to December, 31, 2003. The aim of the study was to examine the correlation between antenatal diagnosis "fetal macrosomia" and the mode of delivery. We found that among the cases with birth weight > or = 4000 g and antenatal diagnosis "fetal macrosomia" the rate of cesarean section was fourfold higher than among the cases without such a diagnosis. There weren't statistically significant correlation between the cases with antenatal diagnosis "fetal macrosomia " and the cases with estimated birth weight < or = 3999g in reference to the mother's age and weight, parity, fundal height and abdominal circumference. There are insignificant differences between both of groups in reference to gestacional age and birth. PMID:15669645

  17. Mode-selective optical packet switching in mode-division multiplexing networks.

    PubMed

    Diamantopoulos, N P; Hayashi, M; Yoshida, Y; Maruta, A; Maruyama, R; Kuwaki, N; Takenaga, K; Uemura, H; Matsuo, S; Kitayama, K

    2015-09-01

    A novel mode-selective optical packet switching, based on mode-multiplexers/demultiplexers and multi-port optical micro-electro-mechanical systems (MEMS) switches, has been proposed and experimentally demonstrated. The experimental demonstration was performed using the LP(01), LP(11a) and LP(11b) modes of a 30-km long mode-division multiplexed few-mode fiber link, utilizing 40 Gb/s, 16-QAM signals. PMID:26368463

  18. The KLT (Karhunen-Loève Transform) to extend SETI searches to broad-band and extremely feeble signals

    NASA Astrophysics Data System (ADS)

    Maccone, Claudio

    2010-12-01

    The KLT (acronym for Karhunen-Loève Transform) is a mathematical algorithm superior to the classical FFT in many regards: The KLT can filter signals out of the background noise over both wide and narrow bands. This is in sharp contrast to the FFT that rigorously applies to narrow-band signals only. The KLT can be applied to random functions that are non-stationary in time, i.e. whose autocorrelation is a function of the two independent variables t1 and t2 separately. Again, this is a sheer advantage of the KLT over the FFT, inasmuch as the FFT rigorously applies to stationary processes only, i.e. processes whose autocorrelation is a function of the absolute value of the difference of t1 and t2 only. The KLT can detect signals embedded in noise to unbelievably small values of the Signal-to-Noise Ratio (SNR), like 10 -3 or so. This particular feature of the KLT is studied in detail in this paper. An excellent filtering algorithm like the KLT, however, comes with a cost that one must be ready to pay for especially in SETI: its computational burden is much higher than for the FFT. In fact, it can be shown that no fast KLT transform can possibly exist and, for an autocorrelation matrix of size N, the calculations must be of the order of N2, rather than N log( N). Nevertheless, for moderate values of N (in the hundreds), the KLT dominates over the FFT, as shown by the numerical simulations. Finally, an important and recent (2007-2008) development in the KLT theory, called the "Bordered Autocorrelation Method" (BAM), is presented. This BAM-KLT method gets around the difficulty of the N2 brunt calculations and ends up in the following unexpected theorem: the KLT of a feeble sinusoidal carrier embedded into a lot of white stationary noise is given by the Fourier transform of the derivative of the largest KLT eigenvalue with respect to the bordering index. This basic result is fully proved analytically in the final sections of this paper by virtue of a new theorem

  19. A New Titanosaurian Braincase from the Cretaceous "Lo Hueco" Locality in Spain Sheds Light on Neuroanatomical Evolution within Titanosauria.

    PubMed

    Knoll, Fabien; Witmer, Lawrence M; Ridgely, Ryan C; Ortega, Francisco; Sanz, Jose Luis

    2015-01-01

    Despite continuous improvements, our knowledge of the neurocranial anatomy of sauropod dinosaurs as a whole is still poor, which is especially true for titanosaurians even though their postcranial remains are common in many Upper Cretaceous sites worldwide. Here we describe a braincase from the uppermost Cretaceous locality of ''Lo Hueco" in Spain that is one of the most complete titanosaurian braincases found so far in Europe. Although the titanosaurian Ampelosaurus sp. is known from the same locality, this specimen is clearly a distinct taxon and presents a number of occipital characters found in Antarctosaurus and Jainosaurus, which are approximately coeval taxa from southern Gondwana. The specimen was subjected to X-ray computed tomographic (CT) scanning, allowing the generation of 3D renderings of the endocranial cavity enclosing the brain, cranial nerves, and blood vessels, as well as the labyrinth of the inner ear. These findings add considerable knowledge to the field of sauropod paleoneuroanatomy in general and titanosaurian endocast diversity in particular. Compared with that of many sauropodomorphs, the endocast appears only slightly flexed in lateral view and bears similarities (e.g., reduction of the rostral dural expansion) with Gondwanan titanosaurians such as Jainosaurus, Bonatitan, and Antarctosaurus. The vestibular system of the inner ear is somewhat contracted (i.e., the radius of the semicircular canals is small), but less so than expected in derived titanosaurians. However, as far as the new specimen and Jainosaurus can be contrasted, and with the necessary caution due to the small sample of comparative data currently available, the two taxa appear more similar to one another in endocast morphology than to other titanosaurians. Recent phylogenetic analyses of titanosaurians have not included virtually any of the taxa under consideration here, and thus the phylogenetic position of the new Spanish titanosaurian--even its generic, let alone

  20. CMB anisotropies from a gradient mode

    NASA Astrophysics Data System (ADS)

    Mirbabayi, Mehrdad; Zaldarriaga, Matias

    2015-03-01

    A linear gradient mode must have no observable dynamical effect on short distance physics. We confirm this by showing that if there was such a gradient mode extending across the whole observable Universe, it would not cause any hemispherical asymmetry in the power of CMB anisotropies, as long as Maldacena's consistency condition is satisfied. To study the effect of the long wavelength mode on short wavelength modes, we generalize the existing second order Sachs-Wolfe formula in the squeezed limit to include a gradient in the long mode and to account for the change in the location of the last scattering surface induced by this mode. Next, we consider effects that are of second order in the long mode. A gradient mode Φ = qṡx generated in Single-field inflation is shown to induce an observable quadrupole moment. For instance, in a matter-dominated model it is equal to Q = 5(qṡx)2/18. This quadrupole can be canceled by superposition of a quadratic perturbation. The result is shown to be a nonlinear extension of Weinberg's adiabatic modes: a long-wavelength physical mode which looks locally like a coordinate transformation.

  1. Interpretation of the nonlinear mode excitation in the ITER gyrotron

    SciTech Connect

    Nusinovich, G. S.; Sinitsyn, O. V.

    2007-11-15

    This study was motivated by an interesting physical effect observed in experiments with a 1 MW, 170 GHz, continuous-wave gyrotron developed at the Japan Atomic Energy Agency for plasma heating and current drive in ITER [see, e.g., Fusion Eng. Des. 55, issues 2-3 (2001)]. In these experiments, the gyrotron switching from a parasitic mode to the operating one was observed with the increase in external magnetic field in the region of hard self-excitation of the operating mode where it cannot be excited from the noise level in the absence of other modes. Below, the theory describing this effect is developed. The switching mechanism caused by merging and disappearance of two (one stable and another unstable) equilibrium states with nonzero amplitudes of both modes is proposed. It is found that the present theory can correctly interpret experimental results qualitatively, but the lack of experimental data does not let the authors carry out some simulations more adequate to experimental conditions.

  2. Enhanced Light Scattering of the Forbidden longitudinal Optical Phonon Mode Studied by Micro-Raman Spectroscopy on Single InN nanowires

    SciTech Connect

    Sutter, E.; Schafer-Nolte, E.O.; Stoica T.; Gotschke, T.; Limbach, F.A.; Sutter, P.; Grutzmacher, D.; Calarco, R.

    2010-08-06

    In the literature, there are controversies on the interpretation of the appearance in InN Raman spectra of a strong scattering peak in the energy region of the unscreened longitudinal optical (LO) phonons, although a shift caused by the phonon-plasmon interaction is expected for the high conductance observed in this material. Most measurements on light scattering are performed on ensembles of InN nanowires (NWs). However, it is important to investigate the behavior of individual nanowires and here we report on micro-Raman measurements on single nanowires. When changing the polarization direction of the incident light from parallel to perpendicular to the wire, the expected reduction of the Raman scattering was observed for transversal optical (TO) and E2 phonon scattering modes, while a strong symmetry-forbidden LO mode was observed independently on the laser polarization direction. Single Mg- and Si-doped crystalline InN nanowires were also investigated. Magnesium doping results in a sharpening of the Raman peaks, while silicon doping leads to an asymmetric broadening of the LO peak. The results can be explained based on the influence of the high electron concentration with a strong contribution of the surface accumulation layer and the associated internal electric field.

  3. 18 CFR 3a.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Purpose. 3a.1 Section 3a.1 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES NATIONAL SECURITY INFORMATION General § 3a.1 Purpose. This part 3a describes...

  4. 22 CFR 3a.1 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 1 2012-04-01 2012-04-01 false Definitions. 3a.1 Section 3a.1 Foreign Relations DEPARTMENT OF STATE GENERAL ACCEPTANCE OF EMPLOYMENT FROM FOREIGN GOVERNMENTS BY MEMBERS OF THE UNIFORMED SERVICES § 3a.1 Definitions. For purposes of this part— (a) Applicant means any person...

  5. 32 CFR 352a.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Purpose. 352a.1 Section 352a.1 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) ORGANIZATIONAL CHARTERS DEFENSE FINANCE AND ACCOUNTING SERVICE (DFAS) § 352a.1 Purpose. Pursuant to the authority vested in the Secretary of Defense under provisions...

  6. 14 CFR 374a.1 - Purpose.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Purpose. 374a.1 Section 374a.1 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) SPECIAL REGULATIONS EXTENSION OF CREDIT BY AIRLINES TO FEDERAL POLITICAL CANDIDATES § 374a.1 Purpose. Section 401...

  7. 32 CFR 242a.1 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Applicability. 242a.1 Section 242a.1 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS PUBLIC MEETING PROCEDURES OF THE BOARD OF REGENTS, UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES § 242a.1 Applicability. These...

  8. 12 CFR 708a.1 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Definitions. 708a.1 Section 708a.1 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING CREDIT UNIONS BANK CONVERSIONS AND MERGERS Conversion of Insured Credit Unions to Mutual Savings Banks § 708a.1 Definitions. As used in this part: Clear and conspicuous means text...

  9. Comparison of candidate methods to distinguish noise modes from system modes in structural identification

    NASA Technical Reports Server (NTRS)

    Longman, Richard W.; Lew, Jiann-Shiun; Juang, Jer-Nan

    1992-01-01

    In modal identification, nonphysical noise or computation modes always appear to help match the input-output data. This paper studies the ability of four criteria to distinguish which modes in a model are noise modes: (1) modal amplitude coherency, (2) the relative contribution of each mode to the pulse response indicated by the mode singular value, (3) the variances of the mode frequencies and damping factors produced by a chosen measurement noise level, and (4) identification of the backward-time in order to let the shift from positive to negative damping of the true system modes distinguish these modes from noise modes. Both simulated and experimental data are used to study the four criteria.

  10. The effect of mixed mode precracking on the mode 1 fracture toughness of composite laminates

    NASA Technical Reports Server (NTRS)

    Shankar, Prashanth; Bascom, Williard D.; Nairn, John A.

    1993-01-01

    We subjected double cantilever beam specimens from four different composite materials to mixed-mode precracking. Three different precracking mode 1 to mode 2 ratios were used--1 to 4, 1 to 1, and 4 to 1. Following precracking the specimens were tested for mode I fracture toughness. The mixed-mode precracking often influenced the mode 1 toughness and its influence persisted for as much as 60 mm of mode 1 crack growth. We tested composites with untoughened matrices, composites with rubber-toughened matrices, and composites with interlayer toughening. Depending on material type and precracking mode ratio, the precracking could cause either a significant increase or a significant decrease in the mode 1 fracture toughness.

  11. Toroidal mode number transition of the edge localized modes in the KSTAR plasmas

    NASA Astrophysics Data System (ADS)

    Lee, J. E.; Yun, G. S.; Kim, M.; Lee, J.; Lee, W.; Park, H. K.; Domier, C. W.; Luhmann, N. C., Jr.; Ko, W. H.; the KSTAR Team

    2015-09-01

    Rapid transitions of the toroidal mode number (n ) have been often detected during the evolution of the edge localized modes (ELMs) in the inter-ELM-crash periods of the KSTAR tokamak plasmas. The mode number transitions accompany changes of the mode frequency ({{f}\\text{mode}} ) (e.g. n changed from 8 to 5 while {{f}\\text{mode}} changed from ~32 to 9 kHz). The observed transition phenomena have been diverse including small and large increase (or decrease) in the mode number and multiple transitions during a single inter-ELM-crash period. Two classes of the mode transitions were identified: non-overlapping transition and overlapping transition. The former case is characterized by the absence of coherent filamentary structure during the transition and the latter case is characterized by co-existence of two coherent filamentary structures with different mode numbers. Each transition process typically lasts a few hundreds to thousands of μs.

  12. Geodesic Acoustic Modes Induced by Energetic Particles

    NASA Astrophysics Data System (ADS)

    Zhou, Tianchun; Berk, Herbert

    2009-11-01

    A global geodesic acoustic mode driven by energetic particles (EGAM) has been observed in JET[1, 2] and DIII D[3, 4]. The mode is to be treated fully kinetically. The descriptions of the background electrons and ions are based on standard high and low bounce frequency expansion respectively with respect to the mode frequency. However, the energetic ions must be treated without any expansion of ratio between their bounce frequency and the mode frequency since they are comparable. Under electrostatic perturbation, we construct a quadratic form for the wave amplitude, from which an integro-differential equation is derived. In the limit where the drift orbit width is small comparison with the mode width, a differential equation for perturbed electrostatic field is obtained. Solution is obtained both analytically and numerically. We find that beam counterinjection enhances the instability of the mode. Landau damping due to thermal species is investigated.

  13. Geodesic Acoustic Modes Induced by Energetic Particles

    NASA Astrophysics Data System (ADS)

    Zhou, Tianchun; Berk, Herbert

    2009-05-01

    A global geodesic acoustic mode driven by energetic particles (EGAM) has been observed in JET[1, 2] and DIII D[3, 4]. The mode is to be treated fully kinetically. The descriptions of the background electrons and ions are based on standard high and low bounce frequency expansion respectively with respect to the mode frequency. However, the energetic ions must be treated without any expansion of ratio between their bounce frequency and the mode frequency since they are comparable. Under electrostatic perturbation, we construct a quadratic form for the wave amplitude, from which an integro-differential equation is derived. In the limit where the drift orbit width is small comparison with the mode width, a differential equation for perturbed electrostatic field is obtained. Solution is obtained both analytically and numerically. We find that beam counterinjection enhances the instability of the mode

  14. Guided wave modes in porous cylinders: Theory.

    PubMed

    Wisse, C J; Smeulders, D M J; Chao, G; van Dongen, M E H

    2007-10-01

    The classical theory of wave propagation in elastic cylinders is extended to poro-elastic mandrel modes. The classical theory predicts the existence of undamped L modes and damped C, I, and Z modes. These waves also appear in poro-elastic mandrels, but all of them become damped because of viscous effects. The presence of the Biot slow bulk wave in the poro-elastic material is responsible for the generation of additional mandrel modes. One of them was already discussed by Feng and Johnson, and the others can be grouped together as so-called D modes. The damping of these D modes is at least as high as the damping of the free-field slow wave. PMID:17902842

  15. Mixed-mode fracture of ceramics

    SciTech Connect

    Petrovic, J.J.

    1985-01-01

    The mixed-mode fracture behavior of ceramic materials is of importance for monolithic ceramics in order to predict the onset of fracture under generalized loading conditions and for ceramic composites to describe crack deflection toughening mechanisms. Experimental data on surface flaw mixed-mode fracture in various ceramics indicate that the flaw-plane normal stress at fracture decreases with increasing in-flaw-plane shear stress, although present data exhibit a fairly wide range in details of this sigma - tau relationship. Fracture from large cracks suggests that Mode II has a greater effect on Mode I fracture than Mode III. A comparison of surface flaw and large crack mixed-mode I-II fracture responses indicated that surface flaw behavior is influenced by shear resistance effects.

  16. Interchange mode excited by trapped energetic ions

    SciTech Connect

    Nishimura, Seiya

    2015-07-15

    The kinetic energy principle describing the interaction between ideal magnetohydrodynamic (MHD) modes with trapped energetic ions is revised. A model is proposed on the basis of the reduced ideal MHD equations for background plasmas and the bounce-averaged drift-kinetic equation for trapped energetic ions. The model is applicable to large-aspect-ratio toroidal devices. Specifically, the effect of trapped energetic ions on the interchange mode in helical systems is analyzed. Results show that the interchange mode is excited by trapped energetic ions, even if the equilibrium states are stable to the ideal interchange mode. The energetic-ion-induced branch of the interchange mode might be associated with the fishbone mode in helical systems.

  17. Processing Mode Causally Influences Emotional Reactivity

    PubMed Central

    Watkins, Ed; Moberly, Nicholas J.; Moulds, Michelle L.

    2008-01-01

    Three studies are reported showing that emotional responses to stress can be modified by systematic prior practice in adopting particular processing modes. Participants were induced to think about positive and negative scenarios in a mode either characteristic of or inconsistent with the abstract-evaluative mind-set observed in depressive rumination, via explicit instructions (Experiments 1 and 2) and via implicit induction of interpretative biases (Experiment 3), before being exposed to a failure experience. In all three studies, participants trained into the mode antithetical to depressive rumination demonstrated less emotional reactivity following failure than participants trained into the mode consistent with depressive rumination. These findings provide evidence consistent with the hypothesis that processing mode modifies emotional reactivity and support the processing-mode theory of rumination. PMID:18540752

  18. Mode Switching and Filtering in Nanowire Lasers.

    PubMed

    Röder, Robert; Sidiropoulos, Themistoklis P H; Buschlinger, Robert; Riediger, Max; Peschel, Ulf; Oulton, Rupert F; Ronning, Carsten

    2016-04-13

    Coherent light sources confining the light below the vacuum wavelength barrier will drive future concepts of nanosensing, nanospectroscopy, and photonic circuits. Here, we directly image the angular emission of such a light source based on single semiconductor nanowire lasers. It is confirmed that the lasing switches from the fundamental mode in a thin ZnO nanowire to an admixture of several transverse modes in thicker nanowires approximately at the multimode cutoff. The mode competition with higher order modes substantially slows down the laser dynamics. We show that efficient photonic mode filtering in tapered nanowires selects the desired fundamental mode for lasing with improved performance including power, efficiency, and directionality important for an optimal coupling between adjacent nanophotonic waveguides. PMID:27007261

  19. Transverse-mode dependence of femtosecond filamentation.

    PubMed

    Song, Zhenming; Zhang, Zhigang; Nakajima, Takashi

    2009-07-20

    We theoretically investigate the transverse-mode dependence of femtosecond filamentation in Ar gas. Three different transverse modes, Bessel, Gaussian, and Laguerre modes, are considered for incident laser pulses. By solving the extended nonlinear Schrödinger equation coupled with the electron density equation, we find that the lengths of the filament and the plasma channel induced by the Bessel incident beam is much longer than the other transverse modes with the same peak intensity, pulse duration, and beam diameter. Moreover we find that the temporal profile of the pulse with the Bessel incident mode is nearly undistorted during the propagation. Since the pulse energy that the Bessel beam can carry is more than one order of magnitude larger than the other modes for the same peak intensity, pulse duration, and beam diameter, the Bessel beam can be a very powerful tool in ultrafast nonlinear optics involving propagation in a Kerr medium. PMID:19654624

  20. Mode-dependent characterization of photonic lanterns.

    PubMed

    Yu, Dawei; Fu, Songnian; Cao, Zizheng; Tang, Ming; Liu, Deming; Giles, Ian; Koonen, Ton; Okonkwo, Chigo

    2016-05-15

    We propose and experimentally demonstrate a simple method for characterizing the power transfer matrix of photonic lanterns (PLs) used for mode division multiplexing (MDM) transmission. Due to the optical reflection arising at output facet of the few-mode fiber (FMF), we are able to detect the power at the individual single-mode fiber (SMF) input port and exploit a series of equations based on the theory of energy conservation to obtain mode-dependent characteristics of the PL, including the property of mode selectivity, insertion loss (IL), and channel-dependent loss (CDL). The proposed method is experimentally verified for both the mode selective and the nonmode selective photonic lanterns. PMID:27176988

  1. Coherent Modes in the Edge of DIII--D H--modes

    NASA Astrophysics Data System (ADS)

    Moyer, R. A.; Lehmer, R.; Boedo, J. A.; Rhodes, T. L.; Rettig, C. L.; Doyle, E. J.; Watkins, J. G.; Groebner, R. J.; Burrell, K. H.

    1997-11-01

    Electrostatic fluctuations in the edge of DIII--D H--modes are often characterized by the presense of a large amplitude, coherent or quasi-coherent mode (f=50--60 kHz; δf=5--20 kHz). This mode is similar to coherent modes in the edge of ohmic discharges in TEXT(Tsui, et al., Phys. Rev. Lett. 70) (1993) 1565. and has also been seen in the edge of H--modes in PBX-M.(Tynan et al., Phys. Plasmas 1) (1994) 3301. The mode is localized to a narrow radial extent just inside the separatrix. In ohmic H--modes, the ``mode'' is a quasi-coherent, localized burst of turbulence. In beam heated discharges, the mode is coherent and dominates the power spectra for both density and potential fluctuations after onsetting 10--30 ms into the H--mode phase. In DIII--D, this mode directly drives particle and convective heat fluxes. Mode characteristics and plasma conditions at onset of the mode will be compared with theoretical predictions of such modes.

  2. Transient analysis mode participation for modal survey target mode selection using MSC/NASTRAN DMAP

    NASA Technical Reports Server (NTRS)

    Barnett, Alan R.; Ibrahim, Omar M.; Sullivan, Timothy L.; Goodnight, Thomas W.

    1994-01-01

    Many methods have been developed to aid analysts in identifying component modes which contribute significantly to component responses. These modes, typically targeted for dynamic model correlation via a modal survey, are known as target modes. Most methods used to identify target modes are based on component global dynamic behavior. It is sometimes unclear if these methods identify all modes contributing to responses important to the analyst. These responses are usually those in areas of hardware design concerns. One method used to check the completeness of target mode sets and identify modes contributing significantly to important component responses is mode participation. With this method, the participation of component modes in dynamic responses is quantified. Those modes which have high participation are likely modal survey target modes. Mode participation is most beneficial when it is used with responses from analyses simulating actual flight events. For spacecraft, these responses are generated via a structural dynamic coupled loads analysis. Using MSC/NASTRAN DMAP, a method has been developed for calculating mode participation based on transient coupled loads analysis results. The algorithm has been implemented to be compatible with an existing coupled loads methodology and has been used successfully to develop a set of modal survey target modes.

  3. The evolution of interface phonon polariton modes in a finite superlattice with a structural defect

    NASA Astrophysics Data System (ADS)

    He, Meng-Dong; Wang, Ling-Ling; Huang, Wei-Qing; Wang, Xin-Jun; Zou, Bing-Suo

    2006-12-01

    Using a transfer matrix method, we derive the dispersion equation for interface phonon-polariton modes (IPPMs) in a finite superlattice (SL) with a structural defect. The numerical results show that, in the nonradiative regime, there exist localized IPPMs (including retardation) inside or outside the Reststrahlen regions defined by the interval [ωTO, ωLO]. The localized IPPMs lie either in the minigaps or below and above the bulk bands, and their transversal electric field amplitudes are located in the vicinity of the defect layer or surface layers. The evolution of the IPPMs localized in the vicinity of a different interface can clearly be tracked. In addition, a brief analysis that radiative IPPMs evolve into nonradiative IPPMs is given.

  4. On modeling the common mode inductor

    NASA Technical Reports Server (NTRS)

    Nave, Mark J.

    1991-01-01

    The common mode inductor is the corner stone of filter design. One of the most important parameters of performance is leakage inductance. The role of leakage inductance in filter performance and current handling is discussed. It is demonstrated that leakage inductance is, in fact, desirable. Underlying physics of operation for the common mode inductor is reviewed. A model is presented which enables the designer to predict the leakage inductance of the common mode choke.

  5. Radially Localized Helicon Modes in Nonuniform Plasma

    SciTech Connect

    Breizman, Boris N.; Arefiev, Alexey V.

    2000-04-24

    A radial density gradient in an axisymmetric cylindrical plasma column forms a potential well for nonaxisymmetric helicon modes (m{ne}0 ). This paper presents an analytic description of such modes in the limit of small longitudinal wave numbers. The corresponding mode equation indicates the possibility of efficient resonant absorption of rf power in helicon discharges at unusually low frequencies. (c) 2000 The American Physical Society.

  6. Multi-Mode Broadband Patch Antenna

    NASA Technical Reports Server (NTRS)

    Romanofsky, Robert R. (Inventor)

    2001-01-01

    A multi-mode broad band patch antenna is provided that allows for the same aperture to be used at independent frequencies such as reception at 19 GHz and transmission at 29 GHz. Furthermore, the multi-mode broadband patch antenna provides a ferroelectric film that allows for tuning capability of the multi-mode broadband patch antenna over a relatively large tuning range. The alternative use of a semiconductor substrate permits reduced control voltages since the semiconductor functions as a counter electrode.

  7. Failure mode analysis to predict product reliability.

    NASA Technical Reports Server (NTRS)

    Zemanick, P. P.

    1972-01-01

    The failure mode analysis (FMA) is described as a design tool to predict and improve product reliability. The objectives of the failure mode analysis are presented as they influence component design, configuration selection, the product test program, the quality assurance plan, and engineering analysis priorities. The detailed mechanics of performing a failure mode analysis are discussed, including one suggested format. Some practical difficulties of implementation are indicated, drawn from experience with preparing FMAs on the nuclear rocket engine program.

  8. Mode 2 fatigue crack growth specimen development

    NASA Technical Reports Server (NTRS)

    Buzzard, R. J.; Gross, B.; Srawley, J. E.

    1983-01-01

    A Mode II test specimen was developed which has potential application in understanding phemonena associated with mixed mode fatigue failures in high performance aircraft engine bearing races. The attributes of the specimen are: it contains one single ended notch, which simplifiers data gathering and reduction; the fatigue crack grous in-line with the direction of load application; a single axis test machine is sufficient to perform testing; and the Mode I component is vanishingly small.

  9. Bile Stress Response in Listeria monocytogenes LO28: Adaptation, Cross-Protection, and Identification of Genetic Loci Involved in Bile Resistance

    PubMed Central

    Begley, Máire; Gahan, Cormac G. M.; Hill, Colin

    2002-01-01

    Bile is one of many barriers that Listeria monocytogenes must overcome in the human gastrointestinal tract in order to infect and cause disease. We demonstrated that stationary-phase cultures of L. monocytogenes LO28 were able to tolerate concentrations of bovine, porcine, and human bile and bile acids well in excess of those encountered in vivo. Strain LO28 was relatively bile resistant compared with other clinical isolates of L. monocytogenes, as well as with Listeria innocua, Salmonella enterica serovar Typhimurium LT2, and Lactobacillus sakei. While exponential-phase L. monocytogenes LO28 cells were exquisitely sensitive to unconjugated bile acids, prior adaptation to sublethal levels of bile acids or heterologous stresses, such as acid, heat, salt, or sodium dodecyl sulfate (SDS), significantly enhanced bile resistance. This adaptive response was independent of protein synthesis, and in the cases of bile and SDS adaptation, occurred in seconds. In order to identify genetic loci involved in the bile tolerance phenotype of L. monocytogenes LO28, transposon (Tn917) and plasmid (pORI19) integration banks were screened for bile-sensitive mutants. The disrupted genes included a homologue of the capA locus required for capsule formation in Bacillus anthracis; a gene encoding the transcriptional regulator ZurR; a homologue of an Escherichia coli gene, lytB, involved in isoprenoid biosynthesis; a gene encoding a homologue of the Bacillus subtilis membrane protein YxiO; and a gene encoding an amino acid transporter with a putative role in pH homeostasis, gadE. Interestingly, all of the identified loci play putative roles in maintenance of the cell envelope or in stress responses. PMID:12450822

  10. Bile stress response in Listeria monocytogenes LO28: adaptation, cross-protection, and identification of genetic loci involved in bile resistance.

    PubMed

    Begley, Máire; Gahan, Cormac G M; Hill, Colin

    2002-12-01

    Bile is one of many barriers that Listeria monocytogenes must overcome in the human gastrointestinal tract in order to infect and cause disease. We demonstrated that stationary-phase cultures of L. monocytogenes LO28 were able to tolerate concentrations of bovine, porcine, and human bile and bile acids well in excess of those encountered in vivo. Strain LO28 was relatively bile resistant compared with other clinical isolates of L. monocytogenes, as well as with Listeria innocua, Salmonella enterica serovar Typhimurium LT2, and Lactobacillus sakei. While exponential-phase L. monocytogenes LO28 cells were exquisitely sensitive to unconjugated bile acids, prior adaptation to sublethal levels of bile acids or heterologous stresses, such as acid, heat, salt, or sodium dodecyl sulfate (SDS), significantly enhanced bile resistance. This adaptive response was independent of protein synthesis, and in the cases of bile and SDS adaptation, occurred in seconds. In order to identify genetic loci involved in the bile tolerance phenotype of L. monocytogenes LO28, transposon (Tn917) and plasmid (pORI19) integration banks were screened for bile-sensitive mutants. The disrupted genes included a homologue of the capA locus required for capsule formation in Bacillus anthracis; a gene encoding the transcriptional regulator ZurR; a homologue of an Escherichia coli gene, lytB, involved in isoprenoid biosynthesis; a gene encoding a homologue of the Bacillus subtilis membrane protein YxiO; and a gene encoding an amino acid transporter with a putative role in pH homeostasis, gadE. Interestingly, all of the identified loci play putative roles in maintenance of the cell envelope or in stress responses. PMID:12450822

  11. Edge Mode Coupling within a Plasmonic Nanoparticle.

    PubMed

    Schmidt, Franz-Philipp; Ditlbacher, Harald; Hohenau, Andreas; Hohenester, Ulrich; Hofer, Ferdinand; Krenn, Joachim R

    2016-08-10

    The coupling of plasmonic nanoparticles can strongly modify their optical properties. Here, we show that the coupling of the edges within a single rectangular particle leads to mode splitting and the formation of bonding and antibonding edge modes. We are able to unambiguously designate the modes due to the high spatial resolution of electron microscopy-based electron energy loss spectroscopy and the comparison with numerical simulations. Our results provide simple guidelines for the interpretation and the design of plasmonic mode spectra. PMID:27427962

  12. Normal Modes of Black Hole Accretion Disks

    SciTech Connect

    Ortega-Rodriguez, Manuel; Silbergleit, Alexander S.; Wagoner, Robert V.; /Stanford U., Phys. Dept. /KIPAC, Menlo Park

    2006-11-07

    This paper studies the hydrodynamical problem of normal modes of small adiabatic oscillations of relativistic barotropic thin accretion disks around black holes (and compact weakly magnetic neutron stars). Employing WKB techniques, we obtain the eigen frequencies and eigenfunctions of the modes for different values of the mass and angular momentum of the central black hole. We discuss the properties of the various types of modes and examine the role of viscosity, as it appears to render some of the modes unstable to rapid growth.

  13. Z mode radiation in Jupiter's magnetosphere

    NASA Technical Reports Server (NTRS)

    Kennel, C. F.; Chen, R. F.; Moses, S. L.; Coroniti, F.; Kurth, W. S.

    1987-01-01

    Results of a survey of the Voyager plasma wave instrument wide-band frames that exhibit a narrow-band emission below the low-frequency cutoff of the continuum band are discussed. The analysis of these waves made it possible to identify them as the slow branch of the X mode, the so-called Z mode. As the Voyager 1 spacecraft approached the plasma sheet on March 8, 1979, the Z mode intensified and then disappeared on plasma sheet entry. This observation is interpreted as evidence of local Z mode generation.

  14. Suspensions with reduced violin string modes

    NASA Astrophysics Data System (ADS)

    Lee, B. H.; Ju, L.; Blair, D. G.

    2006-03-01

    We discuss the possibility of significantly reducing the number and Q-factor of violin string modes in the mirror suspension. Simulations of a bar-flexure suspension and an orthogonal ribbon have shown a reduction in the number of violin string modes when compared to a normal ribbon suspension. By calculating the expected suspension thermal noise, we find that the orthogonal ribbon provides a promising suspension alternative. A lower number of violin modes oscillating in the direction of the laser and a reduction in violin mode peak values of at least 23dB can be achieved with a slight increase in thermal noise above 40Hz.

  15. Majorana Zero Modes in Graphene

    NASA Astrophysics Data System (ADS)

    San-Jose, P.; Lado, J. L.; Aguado, R.; Guinea, F.; Fernández-Rossier, J.

    2015-10-01

    A clear demonstration of topological superconductivity (TS) and Majorana zero modes remains one of the major pending goals in the field of topological materials. One common strategy to generate TS is through the coupling of an s -wave superconductor to a helical half-metallic system. Numerous proposals for the latter have been put forward in the literature, most of them based on semiconductors or topological insulators with strong spin-orbit coupling. Here, we demonstrate an alternative approach for the creation of TS in graphene-superconductor junctions without the need for spin-orbit coupling. Our prediction stems from the helicity of graphene's zero-Landau-level edge states in the presence of interactions and from the possibility, experimentally demonstrated, of tuning their magnetic properties with in-plane magnetic fields. We show how canted antiferromagnetic ordering in the graphene bulk close to neutrality induces TS along the junction and gives rise to isolated, topologically protected Majorana bound states at either end. We also discuss possible strategies to detect their presence in graphene Josephson junctions through Fraunhofer pattern anomalies and Andreev spectroscopy. The latter, in particular, exhibits strong unambiguous signatures of the presence of the Majorana states in the form of universal zero-bias anomalies. Remarkable progress has recently been reported in the fabrication of the proposed type of junctions, which offers a promising outlook for Majorana physics in graphene systems.

  16. Majorana Zero Modes in Graphene

    NASA Astrophysics Data System (ADS)

    San-Jose, Pablo; Lado, Jose L.; Aguado, Ramón; Guinea, Francisco; Fernández-Rossier, Joaquín

    A clear demonstration of topological superconductivity (TS) and Majorana zero modes remains one of the major pending goal in the field of topological materials. One common strategy to generate TS is through the coupling of an s-wave superconductor to a helical half-metallic system. Numerous proposals for the latter have been put forward in the literature, most of them based on semiconductors or topological insulators with strong spin-orbit coupling. Here we demonstrate an alternative approach for the creation of TS in graphene/superconductor junctions without the need of spin-orbit coupling. Our prediction stems from the helicity of graphene's zero Landau level edge states in the presence of interactions, and on the possibility, experimentally demonstrated, to tune their magnetic properties with in-plane magnetic fields. We show how canted antiferromagnetic ordering in the graphene bulk close to neutrality induces TS along the junction, and gives rise to isolated, topologically protected Majorana bound states at either end. We also discuss possible strategies to detect their presence. Remarkable progress has recently been reported in the fabrication of the proposed type of junctions, which offers a promising outlook for Majorana physics in graphene systems.

  17. Large-mode enhancement cavities.

    PubMed

    Carstens, Henning; Holzberger, Simon; Kaster, Jan; Weitenberg, Johannes; Pervak, Volodymyr; Apolonski, Alexander; Fill, Ernst; Krausz, Ferenc; Pupeza, Ioachim

    2013-05-01

    In passive enhancement cavities the achievable power level is limited by mirror damage. Here, we address the design of robust optical resonators with large spot sizes on all mirrors, a measure that promises to mitigate this limitation by decreasing both the intensity and the thermal gradient on the mirror surfaces. We introduce a misalignment sensitivity metric to evaluate the robustness of resonator designs. We identify the standard bow-tie resonator operated close to the inner stability edge as the most robust large-mode cavity and implement this cavity with two spherical mirrors with 600 mm radius of curvature, two plane mirrors and a round trip length of 1.2 m, demonstrating a stable power enhancement of near-infrared laser light by a factor of 2000. Beam radii of 5.7 mm × 2.6 mm (sagittal × tangential 1/e(2) intensity radius) on all mirrors are obtained. We propose a simple all-reflective ellipticity compensation scheme. This will enable a significant increase of the attainable power and intensity levels in enhancement cavities. PMID:23670017

  18. Transverse mode coupling in RHIC

    SciTech Connect

    Raka, E.

    1990-02-21

    In the Proceedings of the Workshop on the RHIC Performance, it was stated that the transverse mode coupling instability, posed a potential intensity limitation for protons. This was based on the expression I{sub b} = 4(E{sub t}/qe) Q{sub s} 4 {radical}{pi} {sigma} {ell}/(Im (Z{sub {perpendicular}}) < {beta}{sub {perpendicular}} > R 3) where E{sub t} is the total energy, q the charge state, Q{sub s} the synchrotron tune, < {beta}{sub {perpendicular}} > the average beta function, R the machine radius, and {sigma}{sub {ell}} the rms bunch length of a Gaussian distribution in longitudinal phase space. For a < {beta}{sub {perpendicular}} > of 55 m and 10{sup 11} protons/bunch, the allowed impedance Z{sub {perpendicular}} for protons at injection, where Q{sub s} = 0.11 {times} 10{sup {minus}3}, would be less than 1.2 M{Omega}/m. The purpose of this report is to discuss the consequences of two factors that were omitted in this equation, which comes from the ZAP program, to RHIC. These are the space charge impedance and the incoherent tune spread of the beam.

  19. Intrinsic Localized Modes in Proteins

    PubMed Central

    Nicolaï, Adrien; Delarue, Patrice; Senet, Patrick

    2015-01-01

    Protein dynamics is essential for proteins to function. Here we predicted the existence of rare, large nonlinear excitations, termed intrinsic localized modes (ILMs), of the main chain of proteins based on all-atom molecular dynamics simulations of two fast-folder proteins and of a rigid α/β protein at 300 K and at 380 K in solution. These nonlinear excitations arise from the anharmonicity of the protein dynamics. The ILMs were detected by computing the Shannon entropy of the protein main-chain fluctuations. In the non-native state (significantly explored at 380 K), the probability of their excitation was increased by a factor between 9 and 28 for the fast-folder proteins and by a factor 2 for the rigid protein. This enhancement in the non-native state was due to glycine, as demonstrated by simulations in which glycine was mutated to alanine. These ILMs might play a functional role in the flexible regions of proteins and in proteins in a non-native state (i.e. misfolded or unfolded states). PMID:26658321

  20. Modes of glutamate receptor gating

    PubMed Central

    Popescu, Gabriela K

    2012-01-01

    Abstract The time course of excitatory synaptic currents, the major means of fast communication between neurons of the central nervous system, is encoded in the dynamic behaviour of post-synaptic glutamate-activated channels. First-pass attempts to explain the glutamate-elicited currents with mathematical models produced reaction mechanisms that included only the most basic functionally defined states: resting vs. liganded, closed vs. open, responsive vs. desensitized. In contrast, single-molecule observations afforded by the patch-clamp technique revealed an unanticipated kinetic multiplicity of transitions: from microseconds-lasting flickers to minutes-long modes. How these kinetically defined events impact the shape of the synaptic response, how they relate to rearrangements in receptor structure, and whether and how they are physiologically controlled represent currently active research directions. Modal gating, which refers to the slowest, least frequently observed ion-channel transitions, has been demonstrated for representatives of all ion channel families. However, reaction schemes have been largely confined to the short- and medium-range time scales. For glutamate receptors as well, modal gating has only recently come under rigorous scrutiny. This article reviews the evidence for modal gating of glutamate receptors and the still developing hypotheses about the mechanism(s) by which modal shifts occur and the ways in which they may impact the time course of synaptic transmission. PMID:22106181

  1. Representation of ideal magnetohydrodynamic modes

    SciTech Connect

    White, R. B.

    2013-02-15

    One of the most fundamental properties of ideal magnetohydrodynamics is the condition that plasma motion cannot change magnetic topology. The conventional representation of ideal magnetohydrodynamic modes by perturbing a toroidal equilibrium field through {delta}B(vector sign)={nabla} Multiplication-Sign ({xi}(vector sign) Multiplication-Sign B(vector sign)) ensures that {delta}B(vector sign){center_dot}{nabla}{psi}=0 at a resonance, with {psi} labelling an equilibrium flux surface. Also useful for the analysis of guiding center orbits in a perturbed field is the representation {delta}B(vector sign)={nabla} Multiplication-Sign {alpha}B(vector sign). These two representations are equivalent, but the vanishing of {delta}B(vector sign){center_dot}{nabla}{psi} at a resonance is necessary but not sufficient for the preservation of field line topology, and a indiscriminate use of either perturbation in fact destroys the original equilibrium flux topology. It is necessary to find the perturbed field to all orders in {xi}(vector sign) to conserve the original topology. The effect of using linearized perturbations on stability and growth rate calculations is discussed.

  2. Intrinsic Localized Modes in Proteins.

    PubMed

    Nicolaï, Adrien; Delarue, Patrice; Senet, Patrick

    2015-01-01

    Protein dynamics is essential for proteins to function. Here we predicted the existence of rare, large nonlinear excitations, termed intrinsic localized modes (ILMs), of the main chain of proteins based on all-atom molecular dynamics simulations of two fast-folder proteins and of a rigid α/β protein at 300 K and at 380 K in solution. These nonlinear excitations arise from the anharmonicity of the protein dynamics. The ILMs were detected by computing the Shannon entropy of the protein main-chain fluctuations. In the non-native state (significantly explored at 380 K), the probability of their excitation was increased by a factor between 9 and 28 for the fast-folder proteins and by a factor 2 for the rigid protein. This enhancement in the non-native state was due to glycine, as demonstrated by simulations in which glycine was mutated to alanine. These ILMs might play a functional role in the flexible regions of proteins and in proteins in a non-native state (i.e. misfolded or unfolded states). PMID:26658321

  3. Transverse multibunch modes for non-rigid bunches, including mode coupling

    SciTech Connect

    Bert, J.S.; Ruth, R.D.

    1995-08-01

    A method for computing transverse multibunch growth rates and frequency shifts in rings, which has been described previously, is applied to the PEP-II B factory. The method allows multibunch modes with different internal-bunch oscillation modes to couple to one another, similar to single-bunch mode coupling. Including coupling between the multibunch modes gives effects similar to those seen in single-bunch mode coupling. These effects occur at currents that are lower than the single-bunch mode coupling threshold.

  4. Discrimination of orbital angular momentum modes of the terahertz vortex beam using a diffractive mode transformer.

    PubMed

    Liu, Changming; Wei, Xuli; Niu, Liting; Wang, Kejia; Yang, Zhengang; Liu, Jinsong

    2016-06-13

    We present an efficient method to discriminate orbital angular momentum (OAM) of the terahertz (THz) vortex beam using a diffractive mode transformer. The mode transformer performs a log-polar coordinate transformation of the input THz vortex beam, which consists of two 3D-printed diffractive elements. A following lens separates each transformed OAM mode to a different lateral position in its focal plane. This method enables a simultaneous measurement over multiple OAM modes of the THz vortex beam. We experimentally demonstrate the measurement of seven individual OAM modes and two multiplexed OAM modes, which is in good agreement with simulations. PMID:27410274

  5. Compact first and second order polarization mode dispersion emulator

    NASA Astrophysics Data System (ADS)

    Zhang, Yang; Li, Shiguang; Yang, Changxi

    2005-08-01

    We propose a 1st and 2nd order polarization mode dispersion emulator (PMDE) with one variable differential group delay (DGD) element using birefringence crystals and four polarization controllers (PCs). Monte Carlo simulations demonstrate that the output 1st and 2nd order polarization mode dispersion (PMD) generated by the PMDE consists with statistic theory. Compared with former PMDEs, this design is tunable, lower-cost, and more integrated for fabrication, which shows response time of 150 ?s, response frequency of 3.8 kHz, working wavelength of 1550 nm, total power consumption of less than 3 W, working range of 0---84 ps and 0---3600 ps2 for 1st and 2nd order PMD emulation, respectively. Also, it is programmable and can be controlled by either singlechip or computer. It can be applied to study the outage probability of optical communication systems due to PMD effect and the effectiveness of PMD compensation.

  6. Generalised Hermite-Gaussian beams and mode transformations

    NASA Astrophysics Data System (ADS)

    Wang, Yi; Chen, Yujie; Zhang, Yanfeng; Chen, Hui; Yu, Siyuan

    2016-05-01

    Generalised Hermite-Gaussian modes (gHG modes), an extended notion of Hermite-Gaussian modes (HG modes), are formed by the summation of normal HG modes with a characteristic function α, which can be used to unite conventional HG modes and Laguerre-Gaussian modes (LG modes). An infinite number of normalised orthogonal modes can thus be obtained by modulation of the function α. The gHG mode notion provides a useful tool in analysis of the deformation and transformation phenomena occurring in propagation of HG and LG modes with astigmatic perturbation.

  7. Flow of neutral interstellar helium into the heliosphere as inferred from IBEX-Lo observations and simulations

    NASA Astrophysics Data System (ADS)

    Bzowski, M.; Kubiak, M. A.; Hlond, M.; Moebius, E.; Leonard, T.; Heirtzler, D.; Kucharek, H.; Bochsler, P. A.; Schwadron, N. A.; Crew, G. B.; McComas, D. J.; Fuselier, S. A.

    2010-12-01

    Previously, a team coordinated through the International Space Science Institute (ISSI) examined direct neutral gas, pickup ion, and UV backscatter observations to produce consensus values for the inflow direction (λ, β), speed v, and temperature T of neutral interstellar helium from the Local Interstellar Cloud (LIC) with relatively small uncertainties. Since then, NASA’s Interstellar Boundary Explorer (IBEX) has started to provide new observations of the interstellar He flow in Earth orbit, with data currently available from the spring seasons of 2009 and 2010. Using a test-particle simulation to compute the spin-phase distributions that IBEX observes during each orbit, we optimize input LIC parameters to best fit the observations. The simulations take into account actual ionization rates as derived from solar EUV observations by SOHO CELIAS SEM, the OMNI solar wind data set, the positions and velocity vectors of the Earth during the actual integration intervals for each orbit, and the IBEX-Lo field-of-view. The simulations were performed on a grid of bulk flow vectors and temperatures, starting with the ISSI team consensus values based most heavily on Ulysses GAS observations (v = 26.4 km/s, T = 6318 K, and λ = 255.4o, β = -5.31o in J2000 coordinates). The Mach number of the flow derived from the IBEX observations is generally lower than derived from Ulysses measurements, which would be consistent with a higher temperature (up to 10 000 K) and/or a lower flow speed (down to ≈22.5 km/s) of the LIC. Based on these findings, the possible LIC parameter sets most probably lie within a narrow range between (λ = 255.4°, β = 5.3°, v = 26.4 km/s, M = 4.5 or T = 10,000 K) and (λ = 261.2°, β = 4.9, v = 23.05 km/s, M = 4.9, or T = 6300 K). At one end of the acceptable range, the parameters agree with the previous values except for the temperature, and at the other end, the temperatures agree, but the direction is different by almost 6° and the velocity is

  8. Measurement of NOx fluxes by eddy covariance from the BT tower, London during the ClearfLo project

    NASA Astrophysics Data System (ADS)

    Lee, James; Helfter, Carole; Nemitz, Eiko; Tremper, Anja; Stocker, Jenny; Carruthers, David

    2014-05-01

    The vast majority of air pollutants are emitted directly into the atmosphere from activities occurring at the Earth's surface. One of the key anthropogenic pollutants is NOx (defined as the sum of NO and NO2), which is emitted as a result of most anthropogenic combustion processes. Whilst the chemical reactions and atmospheric processing of NOx are reasonably well understood, and can be modelled with some skill, large uncertainties arise in models due to uncertainty associated with the rate of emissions. In recent years it has become clear that measured trends in certain pollutants, for example NO2, have not followed trends predicted by inventories. Continued exceedances of certain air pollution targets are of significant concern to governments, who have identified reducing this uncertainty associated with emissions as key evidence need. As part of the UK Natural Environment Research Council (NERC) Clean Air for London (ClearfLo) project, concentrations and fluxes of NOx were measured from the top of the BT tower, which is a 188m high telecommunications tower, situated in central London (51o31'17.4'N; 0o8'20.04W). The tower is surrounded by a mixture of commercial and residential buildings with an average height of 15 m. The typical daytime flux footprint of the tower is dominated by commercial/residential buildings and roads (82%) but also includes urban parkland (13%) and impervious ground (5%). High time resolution (10 Hz) chemiluminescence measurements of NO and NO2 (photolytic conversion to NO followed by chemiluminescence) were combined with fast turbulence measurements from a sonic anemometer to calculate fluxes using the eddy covariance technique. In brief, NOx fluxes per notional half-hourly averaging period were obtained by maximising the covariance between instantaneous (i.e. mean for the averaging period subtracted from each 10 Hz data point) fluctuations of NOx mixing ratio and vertical wind velocity. 24 hour NOx flux measurements were made on 36 days

  9. Excitation of (2,1) neoclassical tearing modes by mode coupling with (1,1) internal mode in EAST

    NASA Astrophysics Data System (ADS)

    Shi, Tonghui; Wan, Baonian; Shen, Biao; Sun, Youwen; Qian, Jinping; Hu, Liqun; Gong, Xianzu; Liu, Guangjun; Luo, Zhengping; Zhong, Guoqiang; Xu, Liqing; Zhang, Jizong; Lin, Shiyao; Jie, Yinxian; Wang, Fudi; Lv, Bo; the EAST Team

    2013-05-01

    Neoclassical tearing modes (NTM) are observed in discharges with auxiliary heating LH+ICRF and LH only during H-mode in EAST. The m/n = 2/1 NTM is triggered by strongly coupling with an m/n = 1/1 internal mode. Here, LH and ICRF are the abbreviations of lower hybrid resonance heating and ion cyclotron resonance frequency heating, respectively. The mode number of the NTM is m/n = 2/1, where m is the poloidal mode number and n is the toroidal mode number. Just before the triggering of NTMs, an m/n = 1/1 internal mode appears in the soft x-ray emission at plasma centre when the intensity of hard x-ray (IHX) reaches a critical value. The mode, characterized by frequency chirping in the spectrum, may be related to suprathermal electrons produced by LH. The saturated magnetic island width wsat of the NTM is strongly correlated with poloidal βp. Normalized βN,onset and the magnetic island critical width wcrit increase with electron temperature Te.

  10. Design and Interpretation of Human Sulfotransferase 1A1 Assays.

    PubMed

    Wang, Ting; Cook, Ian; Leyh, Thomas S

    2016-04-01

    The human sulfotransferases (SULTs) regulate the activities of hundreds, if not thousands, of small molecule metabolites via transfer of the sulfuryl-moiety (-SO3) from the nucleotide donor, 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to the hydroxyls and amines of the recipients. Our understanding of the molecular basis of SULT catalysis has expanded considerably in recent years. The basic kinetic mechanism of these enzymes, previously thought to be ordered, has been redefined as random for SULT2A1, a representative member of the superfamily. An active-site cap whose structure and dynamics are highly responsive to nucleotides was discovered and shown to be critical in determining SULT selectivity, a topic of longstanding interest to the field. We now realize that a given SULT can operate in two specificity modes-broad and narrow-depending on the disposition of the cap. More recent work has revealed that the caps of the SULT1A1 are controlled by homotropic allosteric interactions between PAPS molecules bound at the dimer's active sites. These interactions cause the catalytic efficiency of SULT1A1 to vary in a substrate-dependent fashion by as much as two orders of magnitude over a range of PAPS concentrations that spans those found in human tissues. SULT catalysis is further complicated by the fact that these enzymes are frequently inhibited by their substrates. This review provides an overview of the mechanistic features of SULT1A1 that are important for the design and interpretation of SULT1A1 assays. PMID:26658224

  11. Subcritical crack growth in soda-lime glass in combined mode I and mode II loading

    NASA Technical Reports Server (NTRS)

    Singh, Dileep; Shetty, Dinesh K.

    1990-01-01

    Subcritical crack growth under mixed-mode loading was studied in soda-lime glass. Pure mode I, combined mode I and mode II, and pure mode II loadings were achieved in precracked disk specimens by loading in diametral compression at selected angles with respect to the symmetric radial crack. Crack growth was monitored by measuring the resistance changes in a microcircuit grid consisting of parallel, electrically conducting grid lines deposited on the surface of the disk specimens by photolithography. Subcritical crack growth rates in pure mode I, pure mode II, and combined mode I and mode II loading could be described by an exponential relationship between crack growth rate and an effective crack driving force derived from a mode I-mode II fracture toughness envelope. The effective crack driving force was based on an empirical representation of the noncoplanar strain energy release rate. Stress intensities for kinked cracks were assessed using the method of caustics and an initial decrease and a subsequent increase in the subcritical crack growth rates of kinked cracks were shown to correlate with the variations of the mode I and the mode II stress intensities.

  12. Led Astray by Hemoglobin A1c

    PubMed Central

    Chen, Jean; Diesburg-Stanwood, Amy; Bodor, Geza; Rasouli, Neda

    2016-01-01

    Hemoglobin A1c (A1c) is used frequently to diagnose and treat diabetes mellitus. Therefore, it is important be aware of factors that may interfere with the accuracy of A1c measurements. This is a case of a rare hemoglobin variant that falsely elevated a nondiabetic patient’s A1c level and led to a misdiagnosis of diabetes. A 67-year-old male presented to endocrine clinic for further management after he was diagnosed with diabetes based on an elevated A1c of 10.7%, which is approximately equivalent to an average blood glucose of 260 mg/dL. Multiple repeat A1c levels remained >10%, but his home fasting and random glucose monitoring ranged from 92 to 130 mg/dL. Hemoglobin electrophoresis and subsequent genetic analysis diagnosed the patient with hemoglobin Wayne, a rare hemoglobin variant. This variant falsely elevates A1c levels when A1c is measured using cation-exchange high-performance liquid chromatography. When the boronate affinity method was applied instead, the patient’s A1c level was actually 4.7%. Though hemoglobin Wayne is clinically silent, this patient was erroneously diagnosed with diabetes and started on an antiglycemic medication. Due to this misdiagnosis, the patient was at risk of escalation in his “diabetes management” and hypoglycemia. Therefore, it is important that providers are aware of factors that may result in hemoglobin A1c inaccuracy including hemoglobin variants. PMID:26848480

  13. Hydrogen local vibrational modes in compound semiconductors

    SciTech Connect

    McCluskey, M.D.

    1998-12-31

    Local vibrational mode (LVM) spectroscopy of hydrogen and deuterium in GaP, AlSb, ZnSe, and GaN has provided important information about the structures of dopant-hydrogen complexes and their interaction with the host lattice. In GaN:Mg, for example, hydrogen binds to a host nitrogen which is adjacent to the magnesium acceptor. In GaP and ZnSe, it has been demonstrated that the temperature dependent shifts of LVM`s are proportional to the lattice thermal energy, a consequence of the anharmonic coupling of the local mode to acoustical phonons. Large hydrostatic pressures have been applied to semiconductors to probe the vibrational properties of hydrogen-related complexes. In GaAs, the pressure dependent shifts of the {sup 12}C-H and {sup 13}C-H stretch modes have positive curvatures, while the shift of the S-H stretch mode has a negative curvature. This may be related to the fact that in the bond-centered C-H complex, the hydrogen is compressed between the carbon acceptor and one gallium host atom, whereas in the S-H complex, the hydrogen occupies an interstitial position and is not crowded by neighboring atoms. If these trends are general, then hydrostatic pressure may be a powerful tool in determining the position of the hydrogen atom(s) in a complex. In AlSb, pressure was utilized to resolve a mystery as to why the Se-D complex gives rise to one stretch mode peak while the Se-H stretch mode splits into three peaks. This anomalous splitting is explained in terms of a new resonant interaction between the stretch mode and combination modes involving a wag mode harmonic and extended lattice phonons. The interaction gives rise to vibrational modes with both localized and extended components. When the temperature or hydrostatic pressure is varied, the modes exhibit anti-crossing behavior.

  14. Mode Transitions in Hall Effect Thrusters

    NASA Technical Reports Server (NTRS)

    Sekerak, Michael J.; Longmier, Benjamin W.; Gallimore, Alec D.; Brown, Daniel L.; Hofer, Richard R.; Polk, James E.

    2013-01-01

    Mode transitions have been commonly observed in Hall Effect Thruster (HET) operation where a small change in a thruster operating parameter such as discharge voltage, magnetic field or mass flow rate causes the thruster discharge current mean value and oscillation amplitude to increase significantly. Mode transitions in a 6-kW-class HET called the H6 are induced by varying the magnetic field intensity while holding all other operating parameters constant and measurements are acquired with ion saturation probes and ultra-fast imaging. Global and local oscillation modes are identified. In the global mode, the entire discharge channel oscillates in unison and azimuthal perturbations (spokes) are either absent or negligible. Downstream azimuthally spaced probes show no signal delay between each other and are very well correlated to the discharge current signal. In the local mode, signals from the azimuthally spaced probes exhibit a clear delay indicating the passage of "spokes" and are not well correlated to the discharge current. These spokes are localized oscillations propagating in the ExB direction that are typically 10-20% of the mean value. In contrast, the oscillations in the global mode can be 100% of the mean value. The transition between global and local modes occurs at higher relative magnetic field strengths for higher mass flow rates or higher discharge voltages. The thrust is constant through mode transition but the thrust-to-power decreased by 25% due to increasing discharge current. The plume shows significant differences between modes with the global mode significantly brighter in the channel and the near-field plasma plume as well as exhibiting a luminous spike on thruster centerline. Mode transitions provide valuable insight to thruster operation and suggest improved methods for thruster performance characterization.

  15. A 1-Joule laser for a 16-fiber injection system

    SciTech Connect

    Honig, J

    2004-04-06

    A 1-J laser was designed to launch light down 16, multi-mode fibers (400-{micro}m-core dia.). A diffractive-optic splitter was designed in collaboration with Digital Optics Corporation (DOC), and was delivered by DOC. Using this splitter, the energy injected into each fiber varied <1%. The spatial profile out of each fiber was such that there were no ''hot spots,'' a flyer could successfully be launched and a PETN pellet could be initiated. Preliminary designs of the system were driven by system efficiency where a pristine TEM{sub 00} laser beam would be required. The laser is a master oscillator, power amplifier (MOPA) consisting of a 4-mm-dia. Nd:YLF rod in the stable, q-switched oscillator and a 9.5-mm-dia. Nd:YLF rod in the double-passed amplifier. Using a TEM{sub 00} oscillator beam resulted in excellent transmission efficiencies through the fibers at lower energies but proved to be quite unreliable at higher energies, causing premature fiber damage, flyer plate rupture, stimulated Raman scattering (SRS), and stimulated Brillouin scattering (SBS). Upon further investigation, it was found that both temporal and spatial beam formatting of the laser were required to successfully initiate the PETN. Results from the single-mode experiments, including fiber damage, SRS and SBS losses, will be presented. In addition, results showing the improvement that can be obtained by proper laser beam formatting will also be presented.

  16. Further decrease in glycated hemoglobin following ingestion of a LoBAG30 diet for 10 weeks compared to 5 weeks in people with untreated type 2 diabetes

    PubMed Central

    2010-01-01

    Background We previously determined that a weight-maintenance, non-ketogenic diet containing 30% carbohydrate (CHO), 30% protein, 40% fat, (30:30:40) (LoBAG30) decreased glycated hemoglobin (%tGHb) from 10.8 to 9.1% over a 5 week period in subjects with untreated type 2 diabetes. Both the fasting glucose and postprandial glucose area were decreased. Our objective in the present 10-week study was to determine: 1) whether the above results could be maintained, or even improved (suggesting a metabolic adaptation) and 2) whether the subjects would accept the diet for this longer time period. In addition, protein balance, and a number of other blood and urine constituents were quantified at 5 and at 10 weeks on the LoBAG30 diet to address metabolic adaptation. Methods Eight men with untreated type 2 diabetes were studied over a 10-week period. Blood was drawn and urine was collected over a 24 hour period at the beginning of the study with subjects ingesting a standard diet of 55% CHO, 15% protein, 30% fat, and at the end of 5 and 10 weeks following ingestion of a LoBAG30 diet. Results Body weight was stable. Fasting glucose decreased by 19% at week 5 and 28% at week 10; 24-h total glucose area decreased by 27% at week 5 and 35% at week 10 compared to baseline. Insulin did not change. Mean %tGHb decreased by 13% at week 5, 25% at week 10, and was still decreasing linearly, indicating that a metabolic adaptation occurred. Serum NEFA, AAN, uric acid, urea, albumin, prealbumin, TSH, Total T3, free T4, B12, folate, homocysteine, creatinine, growth hormone and renin did not differ between weeks 5 and 10. IGF-1 increased modestly. Urinary glucose decreased; urinary pH and calcium were similar. Conclusions A LoBAG30 diet resulted in continued improvement in glycemic control. This improvement occurred without significant weight loss, with unchanged insulin and glucagon profiles, and without deterioration in serum lipids, blood pressure or kidney function. Extending the duration

  17. Geiger-mode ladar cameras

    NASA Astrophysics Data System (ADS)

    Yuan, Ping; Sudharsanan, Rengarajan; Bai, Xiaogang; Boisvert, Joseph; McDonald, Paul; Labios, Eduardo; Morris, Bryan; Nicholson, John P.; Stuart, Gary M.; Danny, Harrison; Van Duyne, Stephen; Pauls, Greg; Gaalema, Stephen

    2011-06-01

    The performance of Geiger-mode LAser Detection and Ranging (LADAR) cameras is primarily defined by individual pixel attributes, such as dark count rate (DCR), photon detection efficiency (PDE), jitter, and crosstalk. However, for the expanding LADAR imaging applications, other factors, such as image uniformity, component tolerance, manufacturability, reliability, and operational features, have to be considered. Recently we have developed new 32×32 and 32×128 Read-Out Integrated Circuits (ROIC) for LADAR applications. With multiple filter and absorber structures, the 50-μm-pitch arrays demonstrate pixel crosstalk less than 100 ppm level, while maintaining a PDE greater than 40% at 4 V overbias. Besides the improved epitaxial and process uniformity of the APD arrays, the new ROICs implement a Non-uniform Bias (NUB) circuit providing 4-bit bias voltage tunability over a 2.5 V range to individually bias each pixel. All these features greatly increase the performance uniformity of the LADAR camera. Cameras based on these ROICs were integrated with a data acquisition system developed by Boeing DES. The 32×32 version has a range gate of up to 7 μs and can cover a range window of about 1 km with 14-bit and 0.5 ns timing resolution. The 32×128 camera can be operated at a frame rate of up to 20 kHz with 0.3 ns and 14-bit time resolution through a full CameraLink. The performance of the 32×32 LADAR camera has been demonstrated in a series of field tests on various vehicles.

  18. Circuit Simulations of a 1 MV LTD for radiography.

    SciTech Connect

    Portillo, Salvador; Johnson, David L.; Leckbee, Joshua J.; Rose, David Vincent; Kim, Alexandre A.; Ziska, Derek Raymond; Chavez, Raymond; Molina, Isidro; Maenchen, John Eric

    2005-07-01

    A 1 MV linear transformer driver (LTD), capable of driving a radiographic diode load, has been built and tested. A circuit model of this accelerator has been developed using the BERTHA circuit simulation code. Simulations are compared to data from power-flow experiments utilizing a large area electron-beam diode load. Results show that the simulation model performs well in modeling the baseline operation of the accelerator. In addition, the circuit model has been used to predict several possible fault modes. Simulations of switch prefires, main capacitor failure, vacuum insulator flashover, and core saturation have been used to estimate the probability of inducing further failures and the impact on the load voltage and current.

  19. Flexible Modes Control Using Sliding Mode Observers: Application to Ares I

    NASA Technical Reports Server (NTRS)

    Shtessel, Yuri B.; Hall, Charles E.; Baev, Simon; Orr, Jeb S.

    2010-01-01

    The launch vehicle dynamics affected by bending and sloshing modes are considered. Attitude measurement data that are corrupted by flexible modes could yield instability of the vehicle dynamics. Flexible body and sloshing modes are reconstructed by sliding mode observers. The resultant estimates are used to remove the undesirable dynamics from the measurements, and the direct effects of sloshing and bending modes on the launch vehicle are compensated by means of a controller that is designed without taking the bending and sloshing modes into account. A linearized mathematical model of Ares I launch vehicle was derived based on FRACTAL, a linear model developed by NASA/MSFC. The compensated vehicle dynamics with a simple PID controller were studied for the launch vehicle model that included two bending modes, two slosh modes and actuator dynamics. A simulation study demonstrated stable and accurate performance of the flight control system with the augmented simple PID controller without the use of traditional linear bending filters.

  20. Reversibility of Intersystem Crossing in the {a}1A1(000) and {a}1A1(010) States of Methylene, CH_2

    NASA Astrophysics Data System (ADS)

    Le, Anh T.; Sears, Trevor; Hall, Gregory

    2015-06-01

    The lowest energy singlet ( {a}1A1) and triplet ( {X}3B1) electronic states of methylene, CH_2, are only separated by 3150 wn, but differ greatly in chemical reactivity. Overall methylene reaction rates and chemical behavior are therefore strongly dependent on collisionally-mediated singlet-triplet interconversion. Collisions with inert partners tend to depopulate the excited singlet state and populate vibrationally excited triplet levels in CH_2. This process is generally considered as irreversible for large molecules, however, this is not the case for small molecules such as CH_2. An investigation of the decay kinetics of CH_2 in the presence of argon and various amounts of oxygen has been carried out using transient frequency modulation (FM) absorption spectroscopy, to monitor ortho and para rotational levels in both the {a}1A1(000) and {a}1A1(010) states. In the {a}1A1(000) state, all observed rotational levels follow double exponential decay kinetics, a direct consequence of reversible intersystem crossing. The relative amplitude of the slower decay component is an indicator of how quickly the reverse crossing from excited triplet levels becomes significant during the reaction and relaxation of singlet methylene. The para rotational levels show more obvious signs of reversibility than ortho rotational levels. Adding oxygen enhances the visibility of reversibility for both ortho and para levels. However, in the {a}1A1(010) state where the FM signal is 5-10 times smaller than the {a}1A1(000) state, there is no evidence of double exponential decay kinetics. Acknowledgments: Work at Brookhaven National Laboratory was carried out under Contract No. DE-AC02-98CH10886 and DE-SC0012704 with the U.S. Department of Energy and supported by its Office of Basic Energy Sciences, Division of Chemical Sciences, Geosciences and Biosciences.

  1. Four-Mode Squeezing For Optical Communications

    NASA Technical Reports Server (NTRS)

    Schumaker, Bonny L.

    1989-01-01

    Experiments demonstrated potential of four-mode squeezing for increasing immunity to noise in fiber-optical communication systems and interferometric devices. Four-mode squeezing reduces quantum noise more than ordinary squeezing and provides partial immunity to non-quantum-mechanical phase noise arising in such media as optical fibers.

  2. Graded-index whispering gallery mode resonators

    NASA Technical Reports Server (NTRS)

    Savchenkov, Anatoliy (Inventor); Maleki, Lutfollah (Inventor); Ilchenko, Vladimir (Inventor); Matsko, Andrey B. (Inventor)

    2005-01-01

    Whispering gallery mode optical resonators which have spatially-graded refractive indices. In one implementation, the refractive index spatially increases with a distance from an exterior surface of such a resonator towards an interior of the resonator to produce substantially equal spectral separations for different whispering gallery modes. An optical coupler may be used with such a resonator to provide proper optical coupling.

  3. Landsat-5 bumper-mode geometric correction

    USGS Publications Warehouse

    Storey, J.C.; Choate, Michael J.

    2004-01-01

    The Landsat-5 Thematic Mapper (TM) scan mirror was switched from its primary operating mode to a backup mode in early 2002 in order to overcome internal synchronization problems arising from long-term wear of the scan mirror mechanism. The backup bumper mode of operation removes the constraints on scan start and stop angles enforced in the primary scan angle monitor operating mode, requiring additional geometric calibration effort to monitor the active scan angles. It also eliminates scan timing telemetry used to correct the TM scan geometry. These differences require changes to the geometric correction algorithms used to process TM data. A mathematical model of the scan mirror's behavior when operating in bumper mode was developed. This model includes a set of key timing parameters that characterize the time-varying behavior of the scan mirror bumpers. To simplify the implementation of the bumper-mode model, the bumper timing parameters were recast in terms of the calibration and telemetry data items used to process normal TM imagery. The resulting geometric performance, evaluated over 18 months of bumper-mode operations, though slightly reduced from that achievable in the primary operating mode, is still within the Landsat specifications when the data are processed with the most up-to-date calibration parameters.

  4. Spectroscopic mode identification in gamma Doradus stars

    NASA Astrophysics Data System (ADS)

    Rylvia Pollard, Karen

    2015-08-01

    The MUSICIAN programme at the University of Canterbury has been successfully identifying frequencies and pulsation modes in many gamma Doradus stars using hundreds of precise, high resolution spectroscopic observations. This paper describes some of these frequency and mode identifications and the emerging patterns of the programme.

  5. The search for solar gravity modes

    NASA Technical Reports Server (NTRS)

    Henning, Harald M.; Scherrer, Philip H.

    1988-01-01

    A solar oscillations observing program of more than 13 yr is reviewed. The observations are most sensitive to low degree solar modes and were used for the study of long period p-mode and g-mode oscillations. At the start of the 1987 observing season (summer) long-standing problems with the instrument were corrected which (along with good weather) allowed the cleanest set of data to date. The search for evidence of g-modes in this data is described. Analysis of this data shows good evidence for g-modes. Various methods were used for mode identification with a statistical search for a simple pattern of even spacing in period selected as the most robust. Using this method, a possible g-mode identification was made with an asymptotic period separation T0 = 37.1 min. This identification is consistent with a rotation splitting of 1.6 MicroHz. Tests with randomly generated spectral peaks find as significant a possible set of modes in only 2 out of 100 cases.

  6. Simultaneous Emotions: Entwining Modes in Children's Books

    ERIC Educational Resources Information Center

    Cadden, Mike

    2005-01-01

    Critics and teachers tend to pay attention to genre and ignore mode as an area of consideration. This study examines three novels for young readers that are comparable in terms of their entwining opposing modes (irony and romance, comedy and tragedy) as a successful crossover strategy for appeal to readers young and old. I share implications for…

  7. Modes of Communication during Jazz Improvisation

    ERIC Educational Resources Information Center

    Seddon, Frederick A.

    2005-01-01

    This study investigated modes of communication adopted by six student jazz musicians during rehearsal and performance. Six one-hour rehearsal sessions and a performance were observed and videotaped for analysis. Results revealed six modes of communication that formed two main categories, verbal and non-verbal, each containing three distinct modes…

  8. Gravitational massive modes from extended gravity

    NASA Astrophysics Data System (ADS)

    Basini, Giuseppe; Capozziello, Salvatore; de Laurentis, Mariafelicia

    2016-02-01

    Further gravitational massive modes emerge by extending the geometrical sector of Hilbert-Einstein theory in the most general theory including curvature invariants. Besides massless spin-2, also spin-0 and spin-2 massive and ghost fields have to be considered. We investigate the possible detectability of such additional modes by the Large Hadron Collider and calculate the detectable energy density of the spectrum.

  9. Multiple Modes of Inquiry in Earth Science

    ERIC Educational Resources Information Center

    Kastens, Kim A.; Rivet, Ann

    2008-01-01

    To help teachers enrich their students' understanding of inquiry in Earth science, this article describes six modes of inquiry used by practicing geoscientists (Earth scientists). Each mode of inquiry is illustrated by using examples of seminal or pioneering research and provides pointers to investigations that enable students to experience these…

  10. Mode Contributions to the Casimir Effect

    NASA Astrophysics Data System (ADS)

    Intravaia, F.; Henkel, C.

    2010-04-01

    Applying a sum-over-modes approach to the Casimir interaction between two plates with finite conductivity, we isolate and study the contributions of surface plasmons and Foucault (eddy current) modes. We show in particular that for the TE-polarization eddy currents provide a repulsive force that cancels, at high temperatures, the Casimir free energy calculated with the plasma model.

  11. On the dispersion of geodesic acoustic modes

    NASA Astrophysics Data System (ADS)

    Smolyakov, A. I.; Bashir, M. F.; Elfimov, A. G.; Yagi, M.; Miyato, N.

    2016-05-01

    The problem of dispersion of geodesic acoustic modes is revisited with two different methods for the solution of the kinetic equation. The dispersive corrections to the mode frequency are calculated by including the m = 2 poloidal harmonics. Our obtained results agree with some earlier results but differ in various ways with other previous works. Limitations and advantages of different approaches are discussed.

  12. Mode suppression means for gyrotron cavities

    DOEpatents

    Chodorow, Marvin; Symons, Robert S.

    1983-08-09

    In a gyrotron electron tube of the gyro-klystron or gyro-monotron type, having a cavity supporting an electromagnetic mode with circular electric field, spurious resonances can occur in modes having noncircular electric field. These spurious resonances are damped and their frequencies shifted by a circular groove in the cavity parallel to the electric field.

  13. Evolution of Protein Binding Modes in Homooligomers

    PubMed Central

    Dayhoff, Judith E.; Shoemaker, Benjamin A.; Bryant, Stephen H.; Panchenko, Anna R.

    2009-01-01

    The evolution of protein interactions cannot be deciphered without a detailed analysis of interaction interfaces and binding modes. We performed a large-scale study of protein homooligomers in terms of their symmetry, interface sizes, and conservation of binding modes. We also focused specifically on the evolution of protein binding modes from nine families of homooligomers and mapped 60 different binding modes and oligomerization states onto the phylogenetic trees of these families. We observed a significant tendency for the same binding modes to be clustered together and conserved within clades on phylogenetic trees; this trend is especially pronounced for close homologs with 70% sequence identity or higher. Some binding modes are conserved among very distant homologs, pointing to their ancient evolutionary origin, while others are very specific for a certain phylogenetic group. Moreover, we found that the most ancient binding modes have a tendency to involve symmetrical (isologous) homodimer binding arrangements with larger interfaces, while recently evolved binding modes more often exhibit asymmetrical arrangements and smaller interfaces. PMID:19879880

  14. Probe Measurements in the H-mode Pedestal Region in the Pegasus Toroidal Experiment

    NASA Astrophysics Data System (ADS)

    Bodner, G. M.; Bongard, M. W.; Fonck, R. J.; Thome, K. E.; Thompson, D. S.

    2014-10-01

    In near-unity aspect ratio Pegasus discharges, Ohmic heating and high-field-side fueling together trigger an L-H mode transition in both limited and diverted configurations. H-mode plasmas are predicted to exhibit pedestals in both the pressure and current density profiles. Operation at A ~ 1 allows for the use of local magnetic and Langmuir probes in the pedestal region. A current pedestal is routinely observed in Pegasus H-mode plasmas, but not in L-mode plasmas or during ELMs. Conventionally, edge pedestal measurements are observed in the edge pressure profile. A triple Langmuir probe has recently been installed in order to investigate the structure of the edge pressure pedestal in Pegasus H-mode discharges and complement the current density profile measurements. Local density and temperature measurements will be collected using the triple Langmuir probe at varying spatial locations to identify edge pressure profiles. These pressure profiles will be measured in both the L-mode and H-mode regimes. The triple probe will additionally be used to observe the turbulence levels before, during, and after the L-H mode transition. Complete density and temperature profiles including the pedestal will be obtained using a combination of Langmuir probe and Thomson scattering measurements. Work supported by US DOE Grant DE-FG02-96ER54375.

  15. Combined mode I-mode III fracture toughness of a particulate reinforced metal-matrix composite

    NASA Technical Reports Server (NTRS)

    Manoharan, M.; Lewandowski, J. J.

    1991-01-01

    The aim of this investigation was to determine the fracture behavior of a particulate reinfored aluminum alloy composite under combined mode I-mode III loading conditions. A modified three-point bend specimen was used to carry out these tests. It was found that the mode I loading condition was energetically most favorable. Addition of mode III components to the system seems to increase the amount of redundant work during fracture without affecting the critical fracture criterion.

  16. LCoS-based mode shaper for few-mode fiber.

    PubMed

    von Hoyningen-Huene, Johannes; Ryf, Roland; Winzer, Peter

    2013-07-29

    Spatial light modulation can be used to address specific fiber modes, as required in mode-division multiplexed systems. We theoretically compare phase-only spatial light modulation to a combination of amplitude and phase spatial light modulation in terms of insertion loss and crosstalk for a fiber supporting 11 LP modes. We experimentally demonstrate selective mode excitation using a Liquid Crystal on Silicon (LCoS) spatial light modulator configured to as phase and amplitude modulator. PMID:23938681

  17. Modal sensitivity analysis for single mode operation in large mode area fiber

    NASA Astrophysics Data System (ADS)

    Sévigny, Benoit; Zhang, Xiaoxing; Garneau, Marc; Faucher, Mathieu; Lizé, Yannick Keith; Holehouse, Nigel

    2008-02-01

    Most of the current large mode area (LMA) fibers are few-moded designs using a large, low numerical aperture (N.A.) core, which promotes mode coupling between core modes and increases bending losses (coupling with claddingmodes), which is undesirable both in terms ofmode area and beamquality. Furthermore, short LMA fiber lengths and small cladding diameters are needed to minimize nonlinear effects and maximize pump absorption respectively in high-power pulsed laser systems. Although gain fiber coiling is a widely used technique to filter-out unwanted modes in LMA fibers, coupling between modes can still occur in component leads and relay fibers. In relay fiber, light coupled into higher-order modes can subsequently be lost in the coiling or continue as higher-order modes, which has the overall effect of reducing the effective transmission of the LP 01 mode and degrading the beam quality. However, maximum transmission of the LP 01 mode is often required in order to have the best possible beam quality (minimal M2). Launching in an LMA fiber with a mode field adapter (MFA)1 provides an excellent way of ensuring maximum LP 01 coupling, but preservation of this mode requires highmodal stability in the output fiber. Small cladding, low N.A. LMA fibers have the disadvantage of being extremely sensitive to external forces in real-life applications, which is unwanted for systems where highly sensitive mode coupling can occur. In this paper, we present a detailed experimental and theoretical analysis of mode coupling sensitivity in LMA fibers as a function of fiber parameters such as N.A., core diameter and cladding diameter. Furthermore, we present the impact of higher N.A. as a solution to increase mode stability in terms of its effect on peak power, effective mode area and coupling efficiency.

  18. New Measurements of Radial Mode Eigenfrequencies

    NASA Astrophysics Data System (ADS)

    Laske, G.; Masters, G.; Dziewonski, A. M.

    2001-12-01

    Radial mode eigenfrequencies are commonly thought to be measured with great ease and precision. The reason for this is that these modes have no geographic pattern so one should be able to measure frequencies from a spectrum observed at any station in the world. Yet, radial modes often seem inconsistent with spherical Earth models that fit all other mode frequencies. It turns out that radial modes are sometimes strongly coupled. The strongest coupling is predicted to be with l=2 modes which is caused by the Earth's hydrostatic ellipticity and aspherical structure of harmonic degree 2. In such cases, mode-coupling due to ellipticity alone can cause a frequency shift for the radial modes by more than 4 microHz. Given that mode frequencies can be measured to within 0.1 microHz, this shift is significant, and some singlets of l=2 modes have indeed been misidentified as the radial mode in the past. Including the spectra of the June 23, 2001 Southern Peru Earthquake we have re-analyzed radial mode eigenfrequencies and present a mode dataset that is internally more consistent than previous ones. We construct spherical Earth models that are consistent with our new data, the Earth's mass and moment of inertia and the current best estimates of ``Reference Normal Mode Data'' (available on the Reference Earth Model web site: //mahi.ucsd.edu/Gabi/rem.html). We seek the smallest perturbation to PREM but update the Q-structure as well as the depths of the upper mantle discontinuities (418~km and 660~km as first order discontinuities; 520~km as change in gradient). The best fitting 1D model is transversely isotropic but we also show isotropic models that fit the data to within their errors. We show that the 220~km discontinuity is not required in the isotropic model but that there exists a trade-off between high shear-velocities in the lid and a low-density zone beneath it. We also investigate ways of truncating transverse isotropy without the 220.

  19. Newer nonconventional modes of mechanical ventilation.

    PubMed

    Singh, Preet Mohinder; Borle, Anuradha; Trikha, Anjan

    2014-07-01

    The conventional modes of ventilation suffer many limitations. Although they are popularly used and are well-understood, often they fail to match the patient-based requirements. Over the years, many small modifications in ventilators have been incorporated to improve patient outcome. The ventilators of newer generation respond to patient's demands by additional feedback systems. In this review, we discuss the popular newer modes of ventilation that have been accepted in to clinical practice. Various intensive care units over the world have found these modes to improve patient ventilator synchrony, decrease ventilator days and improve patient safety. The various modes discusses in this review are: Dual control modes (volume assured pressure support, volume support), Adaptive support ventilation, proportional assist ventilation, mandatory minute ventilation, Bi-level airway pressure release ventilation, (BiPAP), neurally adjusted ventilatory assist and NeoGanesh. Their working principles with their advantages and clinical limitations are discussed in brief. PMID:25114434

  20. Intrinsic component mode synthesis and plate vibrations

    NASA Astrophysics Data System (ADS)

    Bourquin, F.; D'Hennezel, F.

    1992-07-01

    A 'fixed-interface' method of component mode synthesis is presented and employed to compute error bounds for the case of Kirchhoff plates. The fixed-interface method exploits particular 'constraint modes' that are used as eigenfunctions for the Poincare-Steklov operator in the domain decomposition. The technique is applied to the computation of error bounds and coupling modes for several variants of plate problems. The definition and number of the component modes required for accurate mode synthesis does not depend on the selected discretization process. This allows the fixed-interface technique to be used for the effective treatment of large 3D elasticity problems with a large number of unknown interfaces.