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Sample records for a1b sres scenario

  1. Coffee Beverage Quality Assessment Based on ETA/CPTEC-HadCM3 Model (A1B-IPCC/SRES Scenario), Southeastern Brazil

    NASA Astrophysics Data System (ADS)

    Giarolla, A.; Resende, N.; Chou, S. C.; Tavares, P. S.; Rodrigues, D. C.

    2012-04-01

    Environmental factors influence the coffee beverage quality and air temperature has a significant importance in this process. The grain maturation occurs very quickly in regions that present high temperatures and sometimes there is not enough time to complete all this phase adequately. In the other hand, with mild temperatures, the grain maturation occurs more slowly and it promotes a better quality beverage. The aim of this study was to assess the coffee beverage quality in the southeastern Brazil, based on climate projections using the Eta-CPTEC regional model driven by four members of an ensemble of the Met Office Hadley Centre Global Coupled climate model (HadCM3). The global model ensemble was run over the 21st century according to IPCC SRES, A1B emissions scenario. Each ensemble member presented different climate sensitivity in the analysis. The Eta-CPTEC-HadCM3 model was configured with a 40-km grid size and was run over the period of 1961-90 to represent a baseline climate, and over the period of 2011-2100 to simulate possible future changes and the effects on the coffee beverage quality. A coffee beverage quality classification, which depends on the annual air temperature proposed by Bressani (2007) and also, a quality coffee beverage sensory classification, based on Camargo and Cortez (1998) were considered in this study. An evaluation of the systematic errors (BIAS) for each member for the period from 1961 to 1990 was made. The results presented by Eta/CPTEC-HadCM3 model indicated that in the case of an occurrence of A1B emission scenario, the coffee beverage quality could be affected in this region due to the fact that the flavor may become stronger and unpleasant caused by rising air temperatures. The BIAS evaluation and subsequent errors removal demonstrated improvement in the scenarios simulations. A short review concerning agronomic techniques to mitigate extreme meteorological events or global warming on coffee crop based on Camargo (2010) also is

  2. Projected dynamics of abiotic risks in boreal forest ecosystems (SRES A1B, B1)

    NASA Astrophysics Data System (ADS)

    Panferov, O.; Ahrends, B.; Doering, C.; Sogachev, A.

    2009-04-01

    The ongoing climate change causes an increasing frequency of weather extremes (Leckebusch et al., 2008), which can result in wide area damage events (drought, windthrows/breaks) within boreal forest ecosystem. The damage effects, however, depend not only on the strength of a driving force itself (e.g. wind speed) but also on combinations of effecting agents and forest structure. Thus, the present study investigates the projected future developments of abiotic risks in different boreal forests during the 21st Century under conditions of SRES scenarios A1B and B1. Climate scenario data of coupled ECHAM5-MPIOM were downscaled by the regional climate model (CLM) to the spatial resolution of 0.2° x 0.2°, using daily time- steps. With these input data the small-scale modelling with coupled process based sub-models (Jansen et al., 2008) was carried out e.g. for Solling region, (Germany) calculating the water and energy balance of forest ecosystems with modified BROOK 90 (Ahrends et al., 2009) and wind loading on trees with 3D ABL model SCADIS (Panferov and Sogachev, 2008). Norway spruce and Scots pine of various ages were chosen as typical tree species for boreal forest ecosystems and cambisols, podzolic cambisols and stagnosols as typical soil types. The risks of drought and windthrow/breaks for a certain forest stand result from daily combinations of soil water characteristics, static and gust wind loads and soil texture. Damaged stands show higher vulnerability and thus - positive feedback to climate forcing (Vygodskaya et al., 2008). Therefore differences of microclimatological conditions in the remaining stand after changes in forest structure (Radler et al, 2008) were taken into account. Modell output was aggregated to 30-years periods and compared to "present conditions" of 1981-2010. The results show an increment of drought risks towards 2100 caused by changes in precipitation pattern and increase of mean air temperature, whereas the A1B scenario is

  3. Dynamics of combined forest damage risks for 21st century (SRES A1B, B1)

    NASA Astrophysics Data System (ADS)

    Panferov, Oleg; Merklein, Johannes; Sogachev, Andrey; Junghans, Udo; Ahrends, Bernd

    2010-05-01

    The ongoing climate change can result in increasing frequency of weather extremes (Leckebusch et al., 2008) which in turn can produce wide area forest damage (windthrows, droughts, insect attacks) within forest ecosystems in Europe. The probability and extent of damage, depend not only on a strength of a driving force itself but especially on combinations of effecting agents and their interactions with forest ecosystem structure and soil properties. The combined effect of several factors which are not the extremes themselves can lead to the biotic and/or abiotic damage so that the combination becomes an extreme event. As soon as a damage event occurs, the forest structure is changed. The changes in forest structure in their turn strengthen or inhibits the influence of different climatic factors thus increase or decrease the probability of the next damage event creating positive or negative feedbacks. To assess the roles of separate meteorological factors and their combinations in forest damage under present and future climatic conditions the coupled model was created in University of Goettingen, as a part of a Decision Support System (Jansen et al, 2008, Panferov et al., 2009). The model combines the 3D ABL Model SCADIS (Panferov and Sogachev, 2008) with modified soil hydrology model BROOK 90 (Federer, 2003, Ahrends et al. 2009) and the model of climate dependent biotic damage. The projected future developments of forest damage events in 21st Century were carried out under conditions of SRES scenarios A1B and B1; the present conditions were evaluated using the measured data of German Weather Service. Climate scenario data of coupled ECHAM5-MPIOM were downscaled by the regional climate model Climate Local Model (CLM) to the spatial resolution of 0.2° x 0.2° and temporal resolution of 24 hours. Using these data as input the small-scale coupled process based modeling was then carried out for example region of Solling, Germany calculating the water and energy balance

  4. Trends of abiotic damage in forest ecosystems in Germany at regional scale under SRES A1B, B1

    NASA Astrophysics Data System (ADS)

    Panferov, O.; Doering, C.; Sogachev, A.; Merklein, J.; Ahrends, B.

    2009-09-01

    Current climate projections indicate that the ongoing climate change may cause an increase of frequency of weather extremes (Leckebusch et al., 2008), which can result in wide area abiotic and consequent biotic damage events (e.g. drought and following insect attacks) within forest ecosystems. The type and degree of damage depends not only on the strength of a primary driving force itself (e.g. wind speed) but also on complex interactions between combinations of effecting agents with above- and belowground forest structure characteristics. The present study investigates the projected trends of abiotic risks factors and their combinations on coniferous and deciduous forests during the 21st Century under conditions of SRES scenarios A1B and B1. The downscaling of ECHAM5-MPIOM by the regional climate model (CLM) to the spatial resolution of 0.2° x 0.2° with daily time-steps is used for the analysis of future climate extremes and their combinations. With these input data the small-scale modeling with coupled process based sub-models (Jansen et al., 2008) was carried out for Solling region, (Central Germany) calculating the water and energy balance of spruce and beech forest ecosystems on cambisols and podzols with BROOK90 (Federer et al. 2003) and wind loading on trees with 3D ABL model SCADIS (Panferov and Sogachev, 2008). The risks of drought or wind damage for a certain forest stand result from combinations of soil water characteristics, static and gust wind loads, which in turn depend on current above- and belowground tree structure and on soil texture. The actual soil water content and forest structure depends on climate-soil-vegetation interactions in previous years. Therefore, differences of microclimatological conditions in the remaining stand after changes in forest structure are taken into account. Model outputs are aggregated to 30-years periods and compared to "present” conditions of 1971-2000. The results demonstrate an increment of abiotic risks

  5. Projections of summertime ozone concentration over East Asia under multiple IPCC SRES emission scenarios

    NASA Astrophysics Data System (ADS)

    Lee, Jae-Bum; Cha, Jun-Seok; Hong, Sung-Chul; Choi, Jin-Young; Myoung, Ji-Su; Park, Rokjin J.; Woo, Jung-Hun; Ho, Changhoi; Han, Jin-Seok; Song, Chang-Keun

    2015-04-01

    We have developed the Integrated Climate and Air Quality Modeling System (ICAMS) through the one-way nesting of global-regional models to examine the changes in the surface ozone concentrations over East Asia under future climate scenarios. Model simulations have been conducted for the present period of 1996-2005 to evaluate the performance of ICAMS. The simulated surface ozone concentrations reproduced the observed monthly mean concentrations at sites in East Asia with high R2 values (0.4-0.9), indicating a successful simulation to capture both spatial and temporal variability. We then performed several model simulations with the six IPCC SRES scenarios (A2, A1B, A1FI, A1T, B1, and B2) for the next three periods, 2016-2025 (the 2020s), 2046-2055 (the 2050s), and 2091-2100 (the 2090s). The model results show that the projected changes of the annual daily mean maximum eight-hour (DM8H) surface ozone concentrations in summertime for East Asia are in the range of 2-8 ppb, -3 to 8 ppb, and -7 to 9 ppb for the 2020s, the 2050s, and the 2090s, respectively, and are primarily determined based on the emission changes of NOx and NMVOC. The maximum increases in the annual DM8H surface ozone and high-ozone events occur in the 2020s for all scenarios except for A2, implying that the air quality over East Asia is likely to get worse in the near future period (the 2020s) than in the far future periods (the 2050s and the 2090s). The changes in the future environment based on IPCC SRES scenarios would also influence the change in the occurrences of high-concentrations events more greatly than that of the annual DM8H surface ozone concentrations. Sensitivity simulations show that the emissions increase is the key factor in determining future regional surface ozone concentrations in the case of a developing country, China, whereas a developed country, Japan would be influenced more greatly by effects of the regional climate change than the increase in emissions.

  6. A coupled model study on the intensification of the Asian summer monsoon in IPCC SRES Scenarios

    NASA Astrophysics Data System (ADS)

    Wei, Min

    2005-11-01

    The Asian summer monsoon is an important part of the climate system. Investigating the response of the Asian summer monsoon to changing concentrations of greenhouse gases and aerosols will be meaningful to understand and predict climate variability and climate change not only in Asia but also globally. In order to diagnose the impacts of future anthropogenic emissions on monsoon climates, a coupled general circulation model of the atmosphere and the ocean has been used at the Max-Planck-Institute for Meteorology. In addition to carbon dioxide, the major well mixed greenhouse gases such as methane, nitrous oxide, several chlorofluorocarbons, and CFC substitute gases are prescribed as a function of time. The sulfur cycle is simulated interactively, and both the direct aerosol effect and the indirect cloud albedo effect are considered. Furthermore, changes in tropospheric ozone have been pre-calculated with a chemical transport model and prescribed as a function of time and space in the climate simulations. Concentrations of greenhouse gases and anthropogenic emissions of sulfur dioxide are prescribed according to observations (1860-1990) and projected into the future (1990-2100) according to the Scenarios A2 and B2 in Special Report on Emissions Scenarios (SRES, Nakićenović et al., 2000) developed by the Intergovernmental Panel on Climate Change (IPCC). It is found that the Indian summer monsoon is enhanced in the scenarios in terms of both mean precipitation and interannual variability. An increase in precipitation is simulated for northern China but a decrease for the southern part. Furthermore, the simulated future increase in monsoon variability seems to be linked to enhanced ENSO variability towards the end of the scenario integrations.

  7. Societal Risk Evaluation Scheme (SRES): Scenario-Based Multi-Criteria Evaluation of Synthetic Biology Applications.

    PubMed

    Cummings, Christopher L; Kuzma, Jennifer

    2017-01-01

    Synthetic biology (SB) applies engineering principles to biology for the construction of novel biological systems designed for useful purposes. From an oversight perspective, SB products come with significant uncertainty. Yet there is a need to anticipate and prepare for SB applications before deployment. This study develops a Societal Risk Evaluation Scheme (SRES) in order to advance methods for anticipatory governance of emerging technologies such as SB. The SRES is based upon societal risk factors that were identified as important through a policy Delphi study. These factors range from those associated with traditional risk assessment, such as health and environmental consequences, to broader features of risk such as those associated with reversibility, manageability, anticipated levels of public concern, and uncertainty. A multi-disciplinary panel with diverse perspectives and affiliations assessed four case studies of SB using the SRES. Rankings of the SRES components are compared within and across the case studies. From these comparisons, we found levels of controllability and familiarity associated with the cases to be important for overall SRES rankings. From a theoretical standpoint, this study illustrates the applicability of the psychometric paradigm to evaluating SB cases. In addition, our paper describes how the SRES can be incorporated into anticipatory governance models as a screening tool to prioritize research, information collection, and dialogue in the face of the limited capacity of governance systems. To our knowledge, this is the first study to elicit data on specific cases of SB with the goal of developing theory and tools for risk governance.

  8. Societal Risk Evaluation Scheme (SRES): Scenario-Based Multi-Criteria Evaluation of Synthetic Biology Applications

    PubMed Central

    2017-01-01

    Synthetic biology (SB) applies engineering principles to biology for the construction of novel biological systems designed for useful purposes. From an oversight perspective, SB products come with significant uncertainty. Yet there is a need to anticipate and prepare for SB applications before deployment. This study develops a Societal Risk Evaluation Scheme (SRES) in order to advance methods for anticipatory governance of emerging technologies such as SB. The SRES is based upon societal risk factors that were identified as important through a policy Delphi study. These factors range from those associated with traditional risk assessment, such as health and environmental consequences, to broader features of risk such as those associated with reversibility, manageability, anticipated levels of public concern, and uncertainty. A multi-disciplinary panel with diverse perspectives and affiliations assessed four case studies of SB using the SRES. Rankings of the SRES components are compared within and across the case studies. From these comparisons, we found levels of controllability and familiarity associated with the cases to be important for overall SRES rankings. From a theoretical standpoint, this study illustrates the applicability of the psychometric paradigm to evaluating SB cases. In addition, our paper describes how the SRES can be incorporated into anticipatory governance models as a screening tool to prioritize research, information collection, and dialogue in the face of the limited capacity of governance systems. To our knowledge, this is the first study to elicit data on specific cases of SB with the goal of developing theory and tools for risk governance. PMID:28052080

  9. Impact of climate change on soil thermal and moisture regimes in Serbia: An analysis with data from regional climate simulations under SRES-A1B.

    PubMed

    Mihailović, D T; Drešković, N; Arsenić, I; Ćirić, V; Djurdjević, V; Mimić, G; Pap, I; Balaž, I

    2016-11-15

    We considered temporal and spatial variations to the thermal and moisture regimes of the most common RSGs (Reference Soil Groups) in Serbia under the A1B scenario for the 2021-2050 and 2071-2100 periods, with respect to the 1961-1990 period. We utilized dynamically downscaled global climate simulations from the ECHAM5 model using the coupled regional climate model EBU-POM (Eta Belgrade University-Princeton Ocean Model). We analysed the soil temperature and moisture time series using simple statistics and a Kolmogorov complexity (KC) analysis. The corresponding metrics were calculated for 150 sites. In the future, warmer and drier regimes can be expected for all RSGs in Serbia. The calculated soil temperature and moisture variations include increases in the mean annual soil temperature (up to 3.8°C) and decreases in the mean annual soil moisture (up to 11.3%). Based on the KC values, the soils in Serbia are classified with respect to climate change impacts as (1) less sensitive (Vertisols, Umbrisols and Dystric Cambisols) or (2) more sensitive (Chernozems, Eutric Cambisols and Planosols).

  10. High water-stressed population estimated by world water resources assessment including human activities under SRES scenarios

    NASA Astrophysics Data System (ADS)

    Kiguchi, M.; Shen, Y.; Kanae, S.; Oki, T.

    2009-04-01

    In an argument of the reduction and the adaptation for the climate change, the evaluation of the influence by the climate change is important. When we argue in adaptation plan from a damage scale and balance with the cost, it is particularly important. Parry et al (2001) evaluated the risks in shortage of water, malaria, food, the risk of the coast flood by temperature function and clarified the level of critical climate change. According to their evaluation, the population to be affected by the shortage of water suddenly increases in the range where temperature increases from 1.5 to 2.0 degree in 2080s. They showed how much we need to reduce emissions in order to draw-down significantly the number at risk. This evaluation of critical climate change threats and targets of water shortage did not include the water withdrawal divided by water availability. Shen et al (2008a) estimated the water withdrawal of projection of future world water resources according to socio-economic driving factors predicted for scenarios A1b, A2, B1, and B2 of the Special Report on Emission Scenarios (SRES). However, these results were in function of not temperature but time. The assessment of the highly water-stressed population considered the socioeconomic development is necessary for a function of the temperature. Because of it is easy to understand to need to reduce emission. We present a multi-GCM analysis of the global and regional populations lived in highly water-stressed basin for a function of the temperature using the socioeconomic data and the outputs of GCMs. In scenario A2, the population increases gradually with warming. On the other hand, the future projection population in scenario A1b and B1 increase gradually until the temperature anomaly exceeds around from +1 to +1.5 degree. After that the population is almost constant. From Shen et al (2008b), we evaluated the HWSP and its ratio in the world with temperature function for scenarios A1B, A2, and B1 by the index of W

  11. Regional aspect of highly water-stressed population estimated by world water resources under SRES scenarios

    NASA Astrophysics Data System (ADS)

    Kiguchi, M.; Shen, Y.; Kanae, S.; Oki, T.

    2008-12-01

    Global and regional populations lived in highly water-stressed basin for a function of the temperature were estimated using the socio-economical data and the outputs of GCMs. In global, the highly water-stressed population in scenario A2 rapidly increased when the anomaly of temperature is exceeding to about +1.5 deg.. In the case of the scenario A1b, the gradient of increase of highly water-stressed population was less than that in the case of the scenario A2. When the value of temperature anomaly was exceeding to about + 1.5 deg., the gradient of increase of highly water-stressed population became loose. On the other hand, the highly water-stressed population in the scenario B1 decreased when the temperature anomaly was exceeding to about +1.2 deg.. According to the estimation of the highly water-stressed population when the effect of climate change was ignored (that is, runoff was not changed), the highly water-stressed population was almost same. This result implied that it is strongly contributed by not the climate change but the socio- economical factors (ex; an irrigated area, increase of industrial water use, increase of population itself). Parry et al. (2001) pointed out that the influence on the water risk by the climate change is serious when the anomaly of temperature is exceeding to +2 deg.. However, our assessment disagrees with their assignment. When the highly water-stressed population assessment is estimated within the social elements (ex., the increase of irrigation demand, industrial demand, and population itself), the climate change is not so effective. Part of this study was financially supported by the Global Environment Research Fund, "S-4" and "S-5", from the Japanese Ministry of the Environment.

  12. Impacts and responses to sea-level rise: a global analysis of the SRES scenarios over the twenty-first century.

    PubMed

    Nicholls, Robert J; Tol, Richard S J

    2006-04-15

    Taking the Special Report on Emission Scenarios (SRES) climate and socio-economic scenarios (A1FI, A2, B1 and B2 'future worlds'), the potential impacts of sea-level rise through the twenty-first century are explored using complementary impact and economic analysis methods at the global scale. These methods have never been explored together previously. In all scenarios, the exposure and hence the impact potential due to increased flooding by sea-level rise increases significantly compared to the base year (1990). While mitigation reduces impacts, due to the lagged response of sea-level rise to atmospheric temperature rise, impacts cannot be avoided during the twenty-first century by this response alone. Cost-benefit analyses suggest that widespread protection will be an economically rational response to land loss due to sea-level rise in the four SRES futures that are considered. The most vulnerable future worlds to sea-level rise appear to be the A2 and B2 scenarios, which primarily reflects differences in the socio-economic situation (coastal population, Gross Domestic Product (GDP) and GDP/capita), rather than the magnitude of sea-level rise. Small islands and deltaic settings stand out as being more vulnerable as shown in many earlier analyses. Collectively, these results suggest that human societies will have more choice in how they respond to sea-level rise than is often assumed. However, this conclusion needs to be tempered by recognition that we still do not understand these choices and significant impacts remain possible. Future worlds which experience larger rises in sea-level than considered here (above 35 cm), more extreme events, a reactive rather than proactive approach to adaptation, and where GDP growth is slower or more unequal than in the SRES futures remain a concern. There is considerable scope for further research to better understand these diverse issues.

  13. Projected SST trends across the Caribbean Sea based on PRECIS downscaling of ECHAM4, under the SRES A2 and B2 scenarios

    NASA Astrophysics Data System (ADS)

    Nurse, Leonard A.; Charlery, John L.

    2016-01-01

    The Caribbean Sea and adjacent land areas are highly sensitive to the projected impacts of global climate change. The countries bordering the Caribbean Sea depend heavily on coastal and marine assets as a major source of livelihood support. Rising sea surface temperatures (SSTs) are known to be associated with coral bleaching, ocean acidification, and other phenomena that threaten livelihoods in the region. The paucity of SST systematic observations in both the Caribbean Sea and adjoining Western Atlantic waters is a limiting factor in the projection of future climate change impacts on the region's marine resources. Remote sensing of SST by satellites began only within the last three decades and although the data collected so far might be insufficient to provide conclusive definitions of long-term SST variations in the Caribbean waters, these data along with the output from climate model simulations provide a useful basis for gaining further insights into plausible SST futures under IPCC SRES scenarios. In this paper, we examine the recent SST records from the NESDIS AVHRR satellite data and NOAA Optimum Interpolation (OI) sea surface temperature V2 and provide a comparative analysis of projected SST changes for the Caribbean Sea up to the end of the twenty-first century, under the SRES A2 and B2 scenarios' simulations of the sea surface skin temperatures (SSsT) using the Hadley Centre's regional model, PRECIS. The implications of these projected SST changes for bleaching of coral reefs, one of the region's most valuable marine resource, and for rainfall are also discussed.

  14. Natural modes of variability in the A1B scenario: Atmospheric forcing anomalies associated with NAO

    NASA Astrophysics Data System (ADS)

    Markovic, Michaela; Klein, Birgit; Mikolajewicz, Uwe; Mathis, Moritz

    2015-04-01

    A global fully coupled climate scenario run based on the Max Plank Institute Ocean Model (MPIOM) is used to disentangle the effect of internal climatic modes, e.g. the North Atlantic Oscillation (NAO), from climate change signals in the North Sea. By placing one grid pole on Central Europe, enhanced spatial resolution for the European seas was obtained (up to 4 km in the German Bight). This allows a regional scale resolution within the global model, without the inherent problems of prescribed lateral boundary conditions. Furthermore, it provides sufficient resolution to study the leading modes of variability in the circulation and climate of the North Sea, as well as their connection to exchange processes with adjacent parts of the North Atlantic. The North Atlantic Oscillation (NAO) is the dominant mode of winter climate variability affecting the North Sea with amplitudes comparable to the climate change signal. Here we investigate in the fully coupled scenario run how the NAO impact the surface heat fluxes, which comprises the sum of the four components: net surface solar radiation, net surface thermal radiation, sensible heat flux, and latent heat flux. In particular, we analyzed NAO+ and NAO- composites. The results show that the largest contributions to the net radiation balance are attributed to the sensible heat flux and the latent heat fluxes. The highest anomalies in both variables are found over the Norwegian Trench which are related to mixed layer dynamics, circulation changes, and changing in the mean wind field. This modification in the mixed layer dynamics, and mean wind fields will be further investigated.

  15. Future projections of insured losses in the German private building sector following the A1B climatic change scenario

    NASA Astrophysics Data System (ADS)

    Held, H.; Gerstengarbe, F.-W.; Hattermann, F.; Pinto, J. G.; Ulbrich, U.; Böhm, U.; Born, K.; Büchner, M.; Donat, M. G.; Kücken, M.; Leckebusch, G. C.; Nissen, K.; Nocke, T.; Österle, H.; Pardowitz, T.; Werner, P. C.; Burghoff, O.; Broecker, U.; Kubik, A.

    2012-04-01

    We present an overview of a complementary-approaches impact project dealing with the consequences of climate change for the natural hazard branch of the insurance industry in Germany. The project was conducted by four academic institutions together with the German Insurance Association (GDV) and finalized in autumn 2011. A causal chain is modeled that goes from global warming projections over regional meteorological impacts to regional economic losses for private buildings, hereby fully covering the area of Germany. This presentation will focus on wind storm related losses, although the method developed had also been applied in part to hail and flood impact losses. For the first time, the GDV supplied their collected set of insurance cases, dating back for decades, for such an impact study. These data were used to calibrate and validate event-based damage functions which in turn were driven by three different types of regional climate models to generate storm loss projections. The regional models were driven by a triplet of ECHAM5 experiments following the A1B scenario which were found representative in the recent ENSEMBLES intercomparison study. In our multi-modeling approach we used two types of regional climate models that conceptually differ at maximum: a dynamical model (CCLM) and a statistical model based on the idea of biased bootstrapping (STARS). As a third option we pursued a hybrid approach (statistical-dynamical downscaling). For the assessment of climate change impacts, the buildings' infrastructure and their economic value is kept at current values. For all three approaches, a significant increase of average storm losses and extreme event return levels in the German private building sector is found for future decades assuming an A1B-scenario. However, the three projections differ somewhat in terms of magnitude and regional differentiation. We have developed a formalism that allows us to express the combined effect of multi-source uncertainty on return

  16. Climatic controls on biophysical interactions in the Black Sea under present day conditions and a potential future (A1B) climate scenario

    NASA Astrophysics Data System (ADS)

    Cannaby, Heather; Fach, Bettina A.; Arkin, Sinan S.; Salihoglu, Baris

    2015-01-01

    A dynamical downscaling approach has been applied to investigate climatic controls on biophysical interactions and lower trophic level dynamics in the Black Sea. Simulations were performed under present day conditions (1980-1999) and a potential future (2080-2099) climate scenario, based on the Intergovernmental Panel for Climate Change A1B greenhouse gas emission scenario. Simulations project a 3.7 °C increase in SST, a 25% increase in the stability of the seasonal thermocline and a 37 day increase in the duration of seasonal stratification. Increased winter temperatures inhibited the formation of Cold Intermediate Layer (CIL) waters resulting in near complete erosion of the CIL, with implications for the ventilation of intermediate water masses and the subduction of riverine nutrients. A 4% increase in nitrate availability within the upper 30 m of the water column reflected an increase in the retention time of river water within the surface mixed-layer. Changes in thermohaline structure, combined with a 27% reduction in positive wind stress curl, forced a distinct change in the structure of the basin-scale circulation. The predominantly cyclonic circulation characteristic of contemporary conditions was reversed within the southern and eastern regions of the basin, where under A1B climatic conditions, anticyclonic circulation prevailed. The change in circulation structure significantly altered the horizontal advection and dispersion of high nutrient river waters originating on the NW self. Net primary production increased by 5% on average, with much spatial variability in the response, linked to advective processes. Phytoplankton biomass also increased by 5% and the higher nutrient environment of the future scenario caused a shift in species composition in favour of larger phytoplankton. No significant change in zooplankton biomass was projected. These results constitute one of many possible future scenarios for the Black Sea, being dependent on the modelling

  17. Climate response to projected changes in short-lived species under an A1B scenario from 2000-2050 in the GISS climate model

    SciTech Connect

    Menon, Surabi; Shindell, Drew T.; Faluvegi, Greg; Bauer, Susanne E.; Koch, Dorothy M.; Unger, Nadine; Menon, Surabi; Miller, Ron L.; Schmidt, Gavin A.; Streets, David G.

    2007-03-26

    We investigate the climate forcing from and response to projected changes in short-lived species and methane under the A1B scenario from 2000-2050 in the GISS climate model. We present a meta-analysis of new simulations of the full evolution of gas and aerosol species and other existing experiments with variations of the same model. The comparison highlights the importance of several physical processes in determining radiative forcing, especially the effect of climate change on stratosphere-troposphere exchange, heterogeneous sulfate-nitrate-dust chemistry, and changes in methane oxidation and natural emissions. However, the impact of these fairly uncertain physical effects is substantially less than the difference between alternative emission scenarios for all short-lived species. The net global mean annual average direct radiative forcing from the short-lived species is .02 W/m{sup 2} or less in our projections, as substantial positive ozone forcing is largely offset by negative aerosol direct forcing. Since aerosol reductions also lead to a reduced indirect effect, the global mean surface temperature warms by {approx}0.07 C by 2030 and {approx}0.13 C by 2050, adding 19% and 17%, respectively, to the warming induced by long-lived greenhouse gases. Regional direct forcings are large, up to 3.8 W/m{sup 2}. The ensemble-mean climate response shows little regional correlation with the spatial pattern of the forcing, however, suggesting that oceanic and atmospheric mixing generally overwhelms the effect of even large localized forcings. Exceptions are the polar regions, where ozone and aerosols may induce substantial seasonal climate changes.

  18. Flying into the future: aviation emissions scenarios to 2050.

    PubMed

    Owen, Bethan; Lee, David S; Lim, Ling

    2010-04-01

    This study describes the methodology and results for calculating future global aviation emissions of carbon dioxide and oxides of nitrogen from air traffic under four of the IPCC/SRES (Intergovernmental Panel on Climate Change/Special Report on Emissions Scenarios) marker scenarios: A1B, A2, B1, and B2. In addition, a mitigation scenario has been calculated for the B1 scenario, requiring rapid and significant technology development and transition. A global model of aircraft movements and emissions (FAST) was used to calculate fuel use and emissions to 2050 with a further outlook to 2100. The aviation emission scenarios presented are designed to interpret the SRES and have been developed to aid in the quantification of the climate change impacts of aviation. Demand projections are made for each scenario, determined by SRES economic growth factors and the SRES storylines. Technology trends are examined in detail and developed for each scenario providing plausible projections for fuel efficiency and emissions control technology appropriate to the individual SRES storylines. The technology trends that are applied are calculated from bottom-up inventory calculations and industry technology trends and targets. Future emissions of carbon dioxide are projected to grow between 2000 and 2050 by a factor in the range of 2.0 and 3.6 depending on the scenario. Emissions of oxides of nitrogen associated with aviation over the same period are projected to grow by between a factor of 1.2 and 2.7.

  19. High resolution interpolation of climate scenarios for the conterminous USA and Alaska derived from general circulation model simulations

    Treesearch

    Linda A. Joyce; David T. Price; Daniel W. McKenney; R. Martin Siltanen; Pia Papadopol; Kevin Lawrence; David P. Coulson

    2011-01-01

    Projections of future climate were selected for four well-established general circulation models (GCM) forced by each of three greenhouse gas (GHG) emissions scenarios, namely A2, A1B, and B1 from the Intergovernmental Panel on Climate Change (IPCC) Special Report on Emissions Scenarios (SRES). Monthly data for the period 1961-2100 were downloaded mainly from the web...

  20. Impact of climate change on Precipitation and temperature under the RCP 8.5 and A1B scenarios in an Alpine Cathment (Alto-Genil Basin,southeast Spain). A comparison of statistical downscaling methods

    NASA Astrophysics Data System (ADS)

    Pulido-Velazquez, David; Juan Collados-Lara, Antonio; Pardo-Iguzquiza, Eulogio; Jimeno-Saez, Patricia; Fernandez-Chacon, Francisca

    2016-04-01

    In order to design adaptive strategies to global change we need to assess the future impact of climate change on water resources, which depends on precipitation and temperature series in the systems. The objective of this work is to generate future climate series in the "Alto Genil" Basin (southeast Spain) for the period 2071-2100 by perturbing the historical series using different statistical methods. For this targeted we use information coming from regionals climate model simulations (RCMs) available in two European projects, CORDEX (2013), with a spatial resolution of 12.5 km, and ENSEMBLES (2009), with a spatial resolution of 25 km. The historical climate series used for the period 1971-2000 have been obtained from Spain02 project (2012) which has the same spatial resolution that CORDEX project (both use the EURO-CORDEX grid). Two emission scenarios have been considered: the Representative Concentration Pathways (RCP) 8.5 emissions scenario, which is the most unfavorable scenario considered in the fifth Assessment Report (AR5) by the Intergovernmental Panel on Climate Change (IPCC), and the A1B emission scenario of fourth Assessment Report (AR4). We use the RCM simulations to create an ensemble of predictions weighting their information according to their ability to reproduce the main statistic of the historical climatology. A multi-objective analysis has been performed to identify which models are better in terms of goodness of fit to the cited statistic of the historical series. The ensemble of the CORDEX and the ENSEMBLES projects has been finally created with nine and four models respectively. These ensemble series have been used to assess the anomalies in mean and standard deviation (differences between the control and future RCM series). A "delta-change" method (Pulido-Velazquez et al., 2011) has been applied to define future series by modifying the historical climate series in accordance with the cited anomalies in mean and standard deviation. A

  1. Response of streamflow to projected climate change scenarios in an eastern Himalayan catchment of India

    NASA Astrophysics Data System (ADS)

    Senzeba, K. T.; Rajkumari, S.; Bhadra, A.; Bandyopadhyay, A.

    2016-04-01

    Snowmelt run-off model (SRM) based on degree-day approach has been employed to evaluate the change in snow-cover depletion and corresponding streamflow under different projected climatic scenarios for an eastern Himalayan catchment in India. Nuranang catchment located at Tawang district of Arunachal Pradesh with an area of 52 km2 is selected for the present study with an elevation range of 3143-4946 m above mean sea level. Satellite images from October to June of the selected hydrological year 2006-2007 were procured from National Remote Sensing Centre, Hyderabad. Snow cover mapping is done using NDSI method. Based on long term meteorological data, temperature and precipitation data of selected hydrological year are normalized to represent present climatic condition. The projected temperature and precipitation data are downloaded from NCAR's GIS data portal for different emission scenarios (SRES), viz., A1B, A2, B1; and IPCC commitment (non-SRES) scenario for different future years (2020, 2030, 2040 and 2050). Projected temperature and precipitation data are obtained at desired location by spatially interpolating the gridded data and then by statistical downscaling using linear regression. Snow depletion curves for all projected scenarios are generated for the study area and compared with conventional depletion curve for present climatic condition. Changes in cumulative snowmelt depth for different future years are highest under A1B and lowest under IPCC commitment, whereas A2 and B1 values are in-between A1B and IPCC commitment. Percentage increase in streamflow for different future years follows almost the same trend as change in precipitation from present climate under all projected climatic scenarios. Hence, it was concluded that for small catchments having seasonal snow cover, the total streamflow under projected climatic scenarios in future years will be primarily governed by the change in precipitation and not by change in snowmelt depth. Advancing of

  2. Probabilistic Climate Scenario Information for Risk Assessment

    NASA Astrophysics Data System (ADS)

    Dairaku, K.; Ueno, G.; Takayabu, I.

    2014-12-01

    Climate information and services for Impacts, Adaptation and Vulnerability (IAV) Assessments are of great concern. In order to develop probabilistic regional climate information that represents the uncertainty in climate scenario experiments in Japan, we compared the physics ensemble experiments using the 60km global atmospheric model of the Meteorological Research Institute (MRI-AGCM) with multi-model ensemble experiments with global atmospheric-ocean coupled models (CMIP3) of SRES A1b scenario experiments. The MRI-AGCM shows relatively good skills particularly in tropics for temperature and geopotential height. Variability in surface air temperature of physical ensemble experiments with MRI-AGCM was within the range of one standard deviation of the CMIP3 model in the Asia region. On the other hand, the variability of precipitation was relatively well represented compared with the variation of the CMIP3 models. Models which show the similar reproducibility in the present climate shows different future climate change. We couldn't find clear relationships between present climate and future climate change in temperature and precipitation. We develop a new method to produce probabilistic information of climate change scenarios by weighting model ensemble experiments based on a regression model (Krishnamurti et al., Science, 1999). The method can be easily applicable to other regions and other physical quantities, and also to downscale to finer-scale dependent on availability of observation dataset. The prototype of probabilistic information in Japan represents the quantified structural uncertainties of multi-model ensemble experiments of climate change scenarios. Acknowledgments: This study was supported by the SOUSEI Program, funded by Ministry of Education, Culture, Sports, Science and Technology, Government of Japan.

  3. Climate change and growth scenarios for California wildfire

    Treesearch

    A.L. Westerling; B.P. Bryant; H.K. Preisler; T.P. Holmes; H.G. Hildalgo; T. Das; S.R. Shrestha

    2011-01-01

    Large wildfire occurrence and burned area are modeled using hydroclimate and landsurface characteristics under a range of future climate and development scenarios. The range of uncertainty for future wildfire regimes is analyzed over two emissions pathways (the Special Report on Emissions Scenarios [SRES] A2 and B1 scenarios); three global climate models (Centre...

  4. Methodologies for Estimating Future Climate Change Scenarios of Surface Solar Radiation

    NASA Astrophysics Data System (ADS)

    Swamy, A.

    2013-12-01

    A variety of methods are available to estimate future solar radiation (SR) scenarios at spatial scales that are appropriate for local climate change impact assessment, but no clear guidelines are available in the literature to decide which methodologies are most suitable for different applications. Three methodologies to guide the estimation of SR are discussed in this study. In Case 1, SR is measured; in Case 2, SR is measured but sparse; and in Case 3, SR is not measured. In Case 1, future SR scenarios are derived using several downscaling methodologies that transfer the large-scale information simulated by global climate models (GCM) to a local scale (measurements). In Case 2, SR is first estimated at the local scale for a longer time period using sparse measured records, then future scenarios are derived using several downscaling methodologies. In Case 3, SR is first estimated at a regional scale for a longer time-period using complete or sparse measured records of SR, from which SR at local scale is estimated. Finally, in Case 3 methodology, the future scenarios are derived using several downscaling methodologies. A lack of observed SR data, has hindered various climate change impact studies. So Case 3 methodology is elaborated using Support vector machine based downscaling. Future scenarios of SR were estimated monthly from simulations of the third-generation Canadian General Circulation Model (CGCM3) for various SRES emission scenarios (A1B, A2, B1, and COMMIT).

  5. The new ENSEMBLES E1 mitigation scenario for future climate simulations

    NASA Astrophysics Data System (ADS)

    Royer, J.-F.; Lowe, J.; Johns, T.; van Vuuren, D.; Stehfest, E.; Denoblet-Ducoudré, N.; Boucher, O.; Rognerud, B.; Huebener, H.

    2009-04-01

    Climate simulations with state-of-the-art earth-system models are required to study the potential impacts of climate change, and possible solutions for avoiding, or reducing, some of its undesirable consequences. Though several emission scenarios have been applied for the IPCC AR4 assessments, the differences in the SRES scenarios result mainly from varying degrees of globalization, the role of environmental and social policy, economic and population growth and the rate of technology development. It seems then necessary to consider also more stringent mitigation pathways which aim eventually to implement a climate mitigation policy. In particular it appears particularly useful to implement and analyse climate scenarios for stabilising the additional anthropogenic radiative forcing to that equivalent to a carbon dioxide concentration at around 450 ppm during the 22nd Century for attempting to match the European Union target of keeping global anthropogenic warming below 2°C above pre-industrial levels. A new set of climate simulations over the 21st century with improved earth-system models has thus been designed by the European modelling groups participating to the European FP6 project ENSEMBLES, as a contribution to the second phase ("Stream 2") of the project. The set-up of the new simulations, though basically similar to that used in the CMIP3 simulations for the IPCC AR4, has been improved by taking into account land-use changes. The simulations cover the recent historical period (1860-2000) and are extended over the the 21st century by two scenarios based on the A1B development path. The A1B scenario has been chosen as the baseline scenario for the ENSEMBLES stream 2 simulations because the strong increase in emissions is consistent with real emissions growth, and in order provide overlap with earlier climate modelling work. Besides the standard A1B SRES scenario, a new stabilisation scenario has been developed so as to limit the long-term radiative forcing to

  6. Modeling future land use scenarios in South Korea: applying the IPCC special report on emissions scenarios and the SLEUTH model on a local scale.

    PubMed

    Han, Haejin; Hwang, YunSeop; Ha, Sung Ryong; Kim, Byung Sik

    2015-05-01

    This study developed three scenarios of future land use/land cover on a local level for the Kyung-An River Basin and its vicinity in South Korea at a 30-m resolution based on the two scenario families of the Intergovernmental Panel on Climate Change (IPCC) Special Report Emissions Scenarios (SRES): A2 and B1, as well as a business-as-usual scenario. The IPCC SRES A2 and B1 were used to define future local development patterns and associated land use change. We quantified the population-driven demand for urban land use for each qualitative storyline and allocated the urban demand in geographic space using the SLEUTH model. The model results demonstrate the possible land use/land cover change scenarios for the years from 2000 to 2070 by examining the broad narrative of each SRES within the context of a local setting, such as the Kyoungan River Basin, constructing narratives of local development shifts and modeling a set of 'best guess' approximations of the future land use conditions in the study area. This study found substantial differences in demands and patterns of land use changes among the scenarios, indicating compact development patterns under the SRES B1 compared to the rapid and dispersed development under the SRES A2.

  7. Modeling Future Land Use Scenarios in South Korea: Applying the IPCC Special Report on Emissions Scenarios and the SLEUTH Model on a Local Scale

    NASA Astrophysics Data System (ADS)

    Han, Haejin; Hwang, YunSeop; Ha, Sung Ryong; Kim, Byung Sik

    2015-05-01

    This study developed three scenarios of future land use/land cover on a local level for the Kyung-An River Basin and its vicinity in South Korea at a 30-m resolution based on the two scenario families of the Intergovernmental Panel on Climate Change (IPCC) Special Report Emissions Scenarios (SRES): A2 and B1, as well as a business-as-usual scenario. The IPCC SRES A2 and B1 were used to define future local development patterns and associated land use change. We quantified the population-driven demand for urban land use for each qualitative storyline and allocated the urban demand in geographic space using the SLEUTH model. The model results demonstrate the possible land use/land cover change scenarios for the years from 2000 to 2070 by examining the broad narrative of each SRES within the context of a local setting, such as the Kyoungan River Basin, constructing narratives of local development shifts and modeling a set of `best guess' approximations of the future land use conditions in the study area. This study found substantial differences in demands and patterns of land use changes among the scenarios, indicating compact development patterns under the SRES B1 compared to the rapid and dispersed development under the SRES A2.

  8. Atmospheric impact on the northwestern Pacific under a global warming scenario

    NASA Astrophysics Data System (ADS)

    Cheon, Woo Geun; Park, Young-Gyu; Yeh, Sang-Wook; Kim, Baek-Min

    2012-08-01

    Eleven climate models, one high-resolution and ten low-resolution, were analyzed to investigate the response of the northwestern Pacific under a global warming scenario. Application of scenario A1B of the Special Report on Emission Scenarios (SRES) weakens (intensifies) the southern (northern) part of the interior subtropical gyre both in high-resolution and low-resolution model. Such a dipole type change is mainly due to a basin-scale dynamic atmosphere-to-ocean process. Namely, under global warming the Hadley circulation is weakened and expanded poleward. The Ferrel circulation is also displaced poleward, leading to weakening of ascending (descending) air motion and a high (low) sea level pressure anomaly in the northwestern (southeastern extratropical) North Pacific. Finally, a negative wind stress curl anomaly developed along the zero wind stress curl line of the present-day climate to enhance the northern part of the gyre. The high-resolution model results show greater changes in the structure of the Kuroshio and Kuroshio Extension, with strong intensification of the Kuroshio Extension front and jet, while in the low-resolution models the changes are small. The Kuroshio between Taiwan and the southern coast of Japan is significantly intensified in the high-resolution model results, but is slightly weakened in the ensemble of the low-resolution models.

  9. Future changes in precipitation of the baiu season under RCP scenarios

    NASA Astrophysics Data System (ADS)

    Okada, Y.; Takemi, T.; Ishikawa, H.

    2014-12-01

    Recently, the relationship between global warming and rainfall during the rainy season, which called the baiu in Japan, has been attracting attention in association with heavy rainfall in this period. In the Innovative Program of Climate Change Projection for the 21st Century, many studies show a delay in the northward march of the baiu front, and significant increase of daily precipitation amounts around western Japan during the late baiu season (e.g., Kusunoki et al. 2011, Kanada et al. 2012). The future climate experiment in these studies was performed under the IPCC SRES A1B scenarios for global warming conditions. In this study, we discuss the future changes in precipitation using calculated 60km-mesh model (MRI-AGCM3.2H) under Representative Concentration Pathways (RCP) scenarios. Support of this dataset is provided by the Meteorological Research Institute (MRI). These dataset are calculated by setting the Yoshimura (YS) scheme mainly.Seasonal progression of future precipitation generally indicates the northward in RCP2.6 and 4.5 scenarios, around western Japan. In RCP6.0 scenario, precipitation intensity is weak compared to the other scenarios. RCP8.5 scenario is calculated by setting three different cumulus schemes (YS, Arakawa-Schubert (AS), and Kain-Fritsch (KF) schemes). RCP8.5 configured in YS scheme showed that the rainband associated with the baiu front is not clear. Moreover, peak is remarkable during late June. In AS scheme, the precipitation area stagnates around 30 N until August. And it in KF scheme shows gradual northward migration.This work was conducted under the Program for Risk Information on Climate Change supported by the Ministry of Education, Culture, Sports, Science, and Technology-Japan (MEXT).

  10. Sea level rise over the Mediterranean: present climate and scenario Simulations

    NASA Astrophysics Data System (ADS)

    Dell'Aquila, A.; Calmanti, S.; Carillo, A.; Rupolo, V.; Ruti, Pm; Sannino, G.; Artale, V.

    2010-09-01

    A regional atmosphere-ocean coupled model (the PROTHEUS system) has been used to estimate sea level rise in the Mediterranean basin. A present climate simulation has been forced by ERA40 covering the period 1958-2001. Another simulation has been forced by the coupled model ECHAM5-MPIOM for the period 1951-2000 and under the scenario SRES A1B for the period 2001-2050. The present climate simulation has been verified in terms of temperature and salinity against observed data, showing good performances both in the mean values and in the variability. Halosteric and thermosteric components have been computed and the total steric sea level has been compared with satellite data. The comparison with altimeter data has been done for the whole Mediterranean and for sub-basins, the capability of the system to reproduce the inter-annual variability of the sea level has been verified. Data from the scenario simulation have been used to evaluate long term trends for the XX and XXI centuries. The modelling tools presented in this work, developed in the framework of CIRCE EU Project RL2 will also contribute to the Med-CORDEX activities.

  11. Sea level rise over the Mediterranean: present climate and scenario simulations

    NASA Astrophysics Data System (ADS)

    Carillo, Adriana; Ruti, Paolo Michele; Rupolo, Volfango; Sannino, Gianmaria; Calmanti, Sandro; Dell'Aquila, Alessandro; Artale, Vincenzo

    2010-05-01

    A regional atmosphere-ocean coupled model (the Protheus system) has been used to estimate sea level rise in the Mediterranean basin. A present climate simulation has been forced by ERA40 covering the period 1958-2001. Another simulation has been forced by the coupled model ECHAM5-MPIOM for the period 1951-2000 and under the scenario SRES A1B for the period 2001-2050. The present climate simulation has been verified in terms of temperature and salinity against observed data, showing good performances both in the mean values and in the variability. Halosteric and thermosteric components have been computed and the total steric sea level has been compared with satellite data. The comparison with altimeter data has been done for the whole Mediterranean and for sub-basins, the capability of the system to reproduce the inter-annual variability of the sea level has been verified. Data from the scenario simulation have been used to evaluate long term trends for the XX and XXI centuries.

  12. Future scenarios for viticultural bioclimatic indices in Europe

    NASA Astrophysics Data System (ADS)

    Santos, João.; Malheiro, Aureliano C.; Fraga, Helder; Pinto, Joaquim G.

    2010-05-01

    Winemaking has a predominant economic, social and environmental relevance in several European countries. Studies addressing the influence of climate variability and change in viticulture are particularly pertinent, as climate is one of the main conditioning factors of this activity. In this context, bioclimatic indices are a useful zoning tool, allowing the description of the suitability of a particular region for wine production. In this study, we compute climatic indices (concerning to thermal and hydrological conditions) for Europe, characterize regions with different viticultural aptitude, and assess possible variations in these regions under a future climate conditions using a state-of-the-art regional climate model. The indices are calculated from climatic variables (mostly daily maximum and minimum temperatures and precipitation) obtained from the NCEP reanalysis dataset. Then, the same indices are calculated for present and future climate conditions using data from the regional climate model COSMO-CLM (Consortium for Small Scale Modelling - Climate Limited-area Modelling). Maps of theses indices for recent-past periods (1961-2008) and for the SRES A1B scenario are considered in order to identify significant changes in their patterns. Results show that climate change is projected to have a significant negative impact in wine quality by increased dryness and cumulative thermal effects during growing seasons in Southern European regions (e.g. Portugal, Spain and Italy). These changes represent an important constraint to grapevine growth and development, making crucial adaptation/mitigation strategies to be adopted. On the other hand, regions of western and central Europe (e.g. southern Britain, northern France and Germany) will benefit from this scenario both in wine quality, and in new potential areas for viticulture. This approach provides a macro-characterization of European areas where grapevines may preferentially grow, as well as their projected changes

  13. Global and regional ocean carbon uptake and climate change: sensitivity to a substantial mitigation scenario

    NASA Astrophysics Data System (ADS)

    Vichi, Marcello; Manzini, Elisa; Fogli, Pier Giuseppe; Alessandri, Andrea; Patara, Lavinia; Scoccimarro, Enrico; Masina, Simona; Navarra, Antonio

    2011-11-01

    Under future scenarios of business-as-usual emissions, the ocean storage of anthropogenic carbon is anticipated to decrease because of ocean chemistry constraints and positive feedbacks in the carbon-climate dynamics, whereas it is still unknown how the oceanic carbon cycle will respond to more substantial mitigation scenarios. To evaluate the natural system response to prescribed atmospheric "target" concentrations and assess the response of the ocean carbon pool to these values, 2 centennial projection simulations have been performed with an Earth System Model that includes a fully coupled carbon cycle, forced in one case with a mitigation scenario and the other with the SRES A1B scenario. End of century ocean uptake with the mitigation scenario is projected to return to the same magnitude of carbon fluxes as simulated in 1960 in the Pacific Ocean and to lower values in the Atlantic. With A1B, the major ocean basins are instead projected to decrease the capacity for carbon uptake globally as found with simpler carbon cycle models, while at the regional level the response is contrasting. The model indicates that the equatorial Pacific may increase the carbon uptake rates in both scenarios, owing to enhancement of the biological carbon pump evidenced by an increase in Net Community Production (NCP) following changes in the subsurface equatorial circulation and enhanced iron availability from extratropical regions. NCP is a proxy of the bulk organic carbon made available to the higher trophic levels and potentially exportable from the surface layers. The model results indicate that, besides the localized increase in the equatorial Pacific, the NCP of lower trophic levels in the northern Pacific and Atlantic oceans is projected to be halved with respect to the current climate under a substantial mitigation scenario at the end of the twenty-first century. It is thus suggested that changes due to cumulative carbon emissions up to present and the projected concentration

  14. The impacts of climate change and environmental management policies on the trophic regimes in the Mediterranean Sea: Scenario analyses

    NASA Astrophysics Data System (ADS)

    Lazzari, P.; Mattia, G.; Solidoro, C.; Salon, S.; Crise, A.; Zavatarelli, M.; Oddo, P.; Vichi, M.

    2014-07-01

    The impacts of climate change and environmental management policies on the Mediterranean Sea were analyzed in multi-annual simulations of carbon cycling in a planktonic ecosystem model. The modeling system is based on a high-resolution coupled physical-biogeochemical ocean model that is off-line and forced by medium-resolution global climate simulations and by estimates of continental and river inputs of freshwater and nutrients. The simulations span the periods 1990-2000 and 2090-2100, assuming the IPCC SRES A1B scenario of climatic change at the end of the century. The effects of three different options on land use, mediated through rivers, are also considered. All scenarios indicate that the increase in temperature fuels an increase in metabolic rates. The gross primary production increases approximately 5% over the present-day figures, but the changes in productivity rates are compensated by augmented community respiration rates, so the net community production is stable with respect to present-day figures. The 21st century simulations are characterized by a reduction in the system biomass and by an enhanced accumulation of semi-labile dissolved organic matter. The largest changes in organic carbon production occur close to rivers, where the influence of changes in future nutrient is higher.

  15. Summer precipitation variability over Southeastern South America in a global warming scenario

    NASA Astrophysics Data System (ADS)

    Junquas, C.; Vera, C.; Li, L.; Le Treut, H.

    2012-05-01

    December-January-February (DJF) rainfall variability in southeastern South America (SESA) is studied in 18 coupled general circulation models from the WCRP/CMIP3 dataset, for present climate and the SRES-A1B climate change scenario. The analysis is made in terms of properties of the first leading pattern of rainfall variability in the region, characterized by a dipole-like structure with centers of action in the SESA and South Atlantic Convergence Zone (SACZ) regions. The study was performed to address two issues: how rainfall variability in SESA would change in a future climate and how much of that change explains the projected increasing trends in the summer mean rainfall in SESA identified in previous works. Positive (negative) dipole events were identified as those DJF seasons with above (below) normal rainfall in SESA and below (above) normal rainfall in the SACZ region. Results obtained from the multi-model ensemble confirm that future rainfall variability in SESA has a strong projection on the changes of seasonal dipole pattern activity, associated with an increase of the frequency of the positive phase. In addition, the frequency increase of positive dipole phase in the twenty first century seems to be associated with an increase of both frequency and intensity of positive SST anomalies in the equatorial Pacific, and with a Rossby wave train-like anomaly pattern linking that ocean basin to South America, which regionally induces favorable conditions for moisture transport convergence and rainfall increase in SESA.

  16. High resolution multi model Climate change scenario over India including first uncertainty assessment

    NASA Astrophysics Data System (ADS)

    Kumar, P.; Wiltshire, A.; Asharaf, S.; Ahrens, B.; Lucas-Picher, P.; Christensen, J. H.; Gobiet, A.; Saeed, F.; Hagemann, S.; Jacob, D.

    2011-12-01

    This study presents the possible regional climate change over SA with a focus over India as simulated by three very-high-resolution regional climate models. The models are driven by the same lateral boundary conditions from two global models (ECHAM5-MPIOM and HadCM3) under the IPCC AR4 SRES A1B scenario at horizontal resolution of ~25km, except one model which is simulated for only one GCM. The results are presented for two time slices 2021-2050 and 2070-2099. The analysis concentrates along precipitation and temperature over land and focuses mainly on the monsoon season. The circulation parameter is also discussed. In general all models show a clear signal of gradual wide-spread warming throughout the 21st century. The ensemble-mean warming evident at the end of 2050 is 1-2K, whereas it is 3-5K at the end of century. The projected pattern of the precipitation change shows spatial variability. The increase in precipitation is noticed over peninsular and coastal areas and no change or decrease over areas away from the ocean. The influence of the driving GCM on projected precipitation change simulated with each RCM is as strong as the variability among the RCMs driven with one GCM. Some results of the first uncertainties assessment are also presented.

  17. Risk factors for skeletal-related events (SREs) and factors affecting SRE-free survival for nonsmall cell lung cancer patients with bone metastases.

    PubMed

    Ulas, Arife; Bilici, Ahmet; Durnali, Ayse; Tokluoglu, Saadet; Akinci, Sema; Silay, Kamile; Oksuzoglu, Berna; Alkis, Necati

    2016-01-01

    Skeletal-related events (SREs) for nonsmall cell lung cancer (NSCLC) patients with bone metastasis lead to serious morbidity. The aim of this study was to determine risk factors for SREs in NSCLC patients with bone metastasis and the factors influencing SRE-free survival and overall survival (OS). From 2000 to 2012, we evaluated retrospectively 835 NSCLC patients. Three hundred and thirty-five of them with bone metastasis were included in the study. SREs and the other prognostic factors were evaluated by univariate and multivariate analysis for SRE-free survival and OS. SREs were detected in 244 patients (72.8 %). The most common SREs were the need for radiotherapy (43.2 %) and malignant hypercalcemia (17.6 %). The median time to first SRE was 3.5 months at the median follow-up of 17 months. A multivariate analysis showed that the presence of bone metastasis at diagnosis (p < 0.001), the number of bone metastasis (p = 0.001), baseline hypercalcemia (p = 0.004), and the presence of palliative radiotherapy (p = 0.04) were independent prognostic factors for SRE-free survival. A logistic regression analysis identified that the presence of bone metastasis at diagnosis [odds ratio (OR), 12.6], number of bone metastasis (OR, 3.05), and baseline hypercalcemia (OR, 0.33) were found to be predictive factors in the developing of SRE. The median OS time for patients with SRE was worse than that for patients without SRE (7 vs 12 months, respectively). For OS, male gender, ECOG performance status (PS), high lactate dehydrogenase (LDH) level, hypoalbuminemia, the presence of bone metastasis at diagnosis, the number of bone metastasis, the presence of SREs, the presence of bisphosphonate therapy, and palliative radiotherapy were independent prognostic indicators for OS by the multivariate analysis. Our results indicated that the frequency of SREs was high and the presence of bone metastasis at the time of diagnosis, baseline hypercalcemia, and multiple bone

  18. Changes of Meiyu system in the future under A1B scenario simulated by MIROC_Hires model

    NASA Astrophysics Data System (ADS)

    Zhu, Jian; Huang, Danqing; Yang, Tao

    2016-02-01

    The Meiyu/Baiu/Changma is an important and unique persistent rainfall over East Asian during the northward progress of the East Asian summer monsoon (EASM) from late spring to middle summer. In this study, changes of Meiyu system under global warming are examined by MIROC_Hires coupled model. The results reveal that the Meiyu system becomes weaker in the warmer future: the large precipitation center shifts to northern China; ratio of Meiyu rainfall to total summer precipitation ratio decreases. For the three-dimensional atmospheric circulation, the configuration of upper and lower jets benefits the heavy rainfall located over the northern China, associated with abundant water vapor transporting to northern China. The heterogeneous warming over land and sea may be a possible reason for the changes of Meiyu system. Larger thermal contrast is indicated between the Asian continent and the western Pacific during the Meiyu period, which may result in the enhanced southerly with abundant water vapor arriving at northern China. Therefore, rainfall over Meiyu region may be suspended.

  19. Modulating the Strength and Threshold of NOTCH Oncogenic Signals by mir-181a-1/b-1

    PubMed Central

    Wang, Song; Schaffert, Steven; Gong, Xue; Yue, Sibiao; Luong, Richard; Min, Hyeyoung; Yashiro-Ohtani, Yumi; Davis, Mark; Pear, Warren; Chen, Chang-Zheng

    2012-01-01

    Oncogenes, which are essential for tumor initiation, development, and maintenance, are valuable targets for cancer therapy. However, it remains a challenge to effectively inhibit oncogene activity by targeting their downstream pathways without causing significant toxicity to normal tissues. Here we show that deletion of mir-181a-1/b-1 expression inhibits the development of Notch1 oncogene-induced T cell acute lymphoblastic leukemia (T-ALL). mir-181a-1/b-1 controls the strength and threshold of Notch activity in tumorigenesis in part by dampening multiple negative feedback regulators downstream of NOTCH and pre-T cell receptor (TCR) signaling pathways. Importantly, although Notch oncogenes utilize normal thymic progenitor cell genetic programs for tumor transformation, comparative analyses of mir-181a-1/b-1 function in normal thymocyte and tumor development demonstrate that mir-181a-1/b-1 can be specifically targeted to inhibit tumor development with little toxicity to normal development. Finally, we demonstrate that mir-181a-1/b-1, but not mir-181a-2b-2 and mir-181-c/d, controls the development of normal thymic T cells and leukemia cells. Together, these results illustrate that NOTCH oncogene activity in tumor development can be selectively inhibited by targeting the molecular networks controlled by mir-181a-1/b-1. PMID:22916024

  20. Forest land suitability in a Mediterranean area under climate change scenarios

    NASA Astrophysics Data System (ADS)

    Muñoz-Rojas, Miriam; Anaya-Romero, María; Kotb Abd-Elmabod, Sameh; De la Rosa, Diego

    2013-04-01

    As a consequence of the increasing level of atmospheric CO2 and air temperatures, global climate is changing leading to warmer and often drier conditions in many forest ecosystems. The Mediterranean area is particularly vulnerable to climate change as a result of a combination of environmental and human factors. An adequate forest management is associated to improvement of habitat suitability for soil and water quality, climate regulation and other important ecosystem services. The MicroLEIS decision support system (MicroLEIS DSS), through its 12 land evaluation models, is a useful tool to assist decision-makers with specific agro-ecological problems. Among the land evaluation models, Sierra was specifically designed to assess forestry land suitability for restoration of semi-natural habitats in marginal agricultural lands. This model selects up to 22 forest species adapted to Mediterranean conditions based on latitude, longitude, physiographic position, useful depth, texture, drainage, pH, summer and winter temperatures, and precipitation. In this research, Sierra model was applied in 35 benchmark sites representative of the natural regions (NUTS2) of a Mediterranean area (Andalusia, Southern Spain) in current and future climate scenarios for the A1B IPPC SRES (Special Report on Emission Scenarios) and the periods 2040, 2070 and 2100. Data was obtained from SEISnet soil database, CDBm climate database and the future climate change variation values of the State Meteorological Agency. The results showed that Pinus Pinea, Pinus halepensis, Quercus Ilex and Quercus suber are the most suitable forest species in actual and future climate scenarios for the selected marginal lands, according to the tolerance ranges for standard soil and climate variables of the forest species. Various forest species showed a potential aptitude for reforestation in future climate scenarios (i.e. Quercus), whereas others such as Castanea Sativa will not be suitable in the study area in 2070

  1. Scenario forecasting changes in the water balance components of the Olenek and Iindigirka river basins due to possible climate change

    NASA Astrophysics Data System (ADS)

    Gusev, Ye. M.; Nasonova, O. N.; Dzhogan, L. Ya.; Kovalev, E. E.

    2015-06-01

    Scenario projections of the dynamics of meteorological characteristics for the basins of the Olenek and Indigirka rivers (the Republic of Sakha) in the XXI century have been obtained for four IPCC global climate change scenarios of SRES family which correspond to specified scenarios of economic, technological, political, and demographic development of human civilization. The projections have been used to calculate scenarios of possible changes in water balance components for the basins under consideration up to the year of 2063. The calculation procedure involves a physically-based model for heat and mass exchange between the land surface and the atmosphere SWAP and climate scenario generator MAGICC/SCENGEN.

  2. Arctic Planning Scenarios: Scenario #1: Defence Scenario

    DTIC Science & Technology

    2011-07-01

    ministre de la Défense nationale, 2011 Abstract With the change in northern climate over the past decade, current policy and media discussions have...scenarios, a scenario development methodology, and a Capability Inventory Tool (CIT) to identify and characterize legislation and policy on the Arctic, with...for Canada to be able to meet its strategy and policy objectives. Résumé Compte tenu des changements survenus dans le climat nordique au cours des

  3. The future of scenarios: issues in developing new climate change scenarios

    NASA Astrophysics Data System (ADS)

    Pitcher, Hugh M.

    2009-04-01

    In September, 2007, the IPCC convened a workshop to discuss how a new set of scenarios to support climate model runs, mitigation analyses, and impact, adaptation and vulnerability research might be developed. The first phase of the suggested new approach is now approaching completion. This article discusses some of the issues raised by scenario relevant research and analysis since the last set of IPCC scenarios were created (IPCC SRES, 2000) that will need to be addressed as new scenarios are developed by the research community during the second phase. These include (1) providing a logic for how societies manage to transition from historical paths to the various future development paths foreseen in the scenarios, (2) long-term economic growth issues, (3) the appropriate GDP metric to use (purchasing power parity or market exchange rates), (4) ongoing issues with moving from the broad geographic and time scales of the emission scenarios to the finer scales needed for impacts, adaptation and vulnerability analyses and (5) some possible ways to handle the urgent request from the policy community for some guidance on scenario likelihoods. The challenges involved in addressing these issues are manifold; the reward is greater credibility and deeper understanding of an analytic tool that does much to form the context within which many issues in addition to the climate problem will need to be addressed.

  4. Dark scenarios

    NASA Astrophysics Data System (ADS)

    Ahonen, Pasi; Alahuhta, Petteri; Daskala, Barbara; Delaitre, Sabine; Hert, Paul De; Lindner, Ralf; Maghiros, Ioannis; Moscibroda, Anna; Schreurs, Wim; Verlinden, Michiel

    In this chapter, we present four "dark scenarios" that highlight the key socio-economic, legal, technological and ethical risks to privacy, identity, trust, security and inclusiveness posed by new AmI technologies. We call them dark scenarios, because they show things that could go wrong in an AmI world, because they present visions of the future that we do not want to become reality. The scenarios expose threats and vulnerabilities as a way to inform policy-makers and planners about issues they need to take into account in developing new policies or updating existing legislation. Before presenting the four scenarios and our analysis of each, we describe the process of how we created the scenarios as well as the elements in our methodology for analysing the scenarios.

  5. Spatial distribution estimation of malaria in northern China and its scenarios in 2020, 2030, 2040 and 2050.

    PubMed

    Song, Yongze; Ge, Yong; Wang, Jinfeng; Ren, Zhoupeng; Liao, Yilan; Peng, Junhuan

    2016-07-07

    Malaria is one of the most severe parasitic diseases in the world. Spatial distribution estimation of malaria and its future scenarios are important issues for malaria control and elimination. Furthermore, sophisticated nonlinear relationships for prediction between malaria incidence and potential variables have not been well constructed in previous research. This study aims to estimate these nonlinear relationships and predict future malaria scenarios in northern China. Nonlinear relationships between malaria incidence and predictor variables were constructed using a genetic programming (GP) method, to predict the spatial distributions of malaria under climate change scenarios. For this, the examples of monthly average malaria incidence were used in each county of northern China from 2004 to 2010. Among the five variables at county level, precipitation rate and temperature are used for projections, while elevation, water density index, and gross domestic product are held at their present-day values. Average malaria incidence was 0.107 ‰ per annum in northern China, with incidence characteristics in significant spatial clustering. A GP-based model fit the relationships with average relative error (ARE) = 8.127 % for training data (R(2) = 0.825) and 17.102 % for test data (R(2) = 0.532). The fitness of GP results are significantly improved compared with those by generalized additive models (GAM) and linear regressions. With the future precipitation rate and temperature conditions in Special Report on Emission Scenarios (SRES) family B1, A1B and A2 scenarios, spatial distributions and changes in malaria incidences in 2020, 2030, 2040 and 2050 were predicted and mapped. The GP method increases the precision of predicting the spatial distribution of malaria incidence. With the assumption of varied precipitation rate and temperature, and other variables controlled, the relationships between incidence and the varied variables appear sophisticated nonlinearity

  6. Changes in future air quality, deposition, and aerosol-cloud interactions under future climate and emission scenarios

    SciTech Connect

    Glotfelty, Timothy; Zhang, Yang; Karamchandani, Prakash; Streets, David G.

    2016-08-01

    The prospect of global climate change will have wide scale impacts, such as ecological stress and human health hazards. One aspect of concern is future changes in air quality that will result from changes in both meteorological forcing and air pollutant emissions. In this study, the GU-WRF/Chem model is employed to simulate the impact of changing climate and emissions following the IPCC AR4 SRES A1B scenario. An average of 4 future years (2020, 2030, 2040, and 2050) is compared against an average of 2 current years (2001 and 2010). Under this scenario, by the Mid-21st century global air quality is projected to degrade with a global average increase of 2.5 ppb in the maximum 8-hr O3 level and of 0.3 mg m3 in 24-hr average PM2.5. However, PM2.5 changes are more regional due to regional variations in primary aerosol emissions and emissions of gaseous precursor for secondary PM2.5. Increasing NOx emissions in this scenario combines with a wetter climate elevating levels of OH, HO2, H2O2, and the nitrate radical and increasing the atmosphere’s near surface oxidation state. This differs from findings under the RCP scenarios that experience declines in OH from reduced NOx emissions, stratospheric recovery of O3, and increases in CH4 and VOCs. Increasing NOx and O3 levels enhances the nitrogen and O3 deposition, indicating potentially enhanced crop damage and ecosystem stress under this scenario. The enhanced global aerosol level results in enhancements in aerosol optical depth, cloud droplet number concentration, and cloud optical thickness. This leads to dimming at the Earth’s surface with a global average reduction in shortwave radiation of 1.2 W m2 . This enhanced dimming leads to a more moderate warming trend and different trends in radiation than those found in NCAR’s CCSM simulation, which does not include the advanced chemistry and aerosol

  7. Changes in future air quality, deposition, and aerosol-cloud interactions under future climate and emission scenarios

    NASA Astrophysics Data System (ADS)

    Glotfelty, Timothy; Zhang, Yang; Karamchandani, Prakash; Streets, David G.

    2016-08-01

    The prospect of global climate change will have wide scale impacts, such as ecological stress and human health hazards. One aspect of concern is future changes in air quality that will result from changes in both meteorological forcing and air pollutant emissions. In this study, the GU-WRF/Chem model is employed to simulate the impact of changing climate and emissions following the IPCC AR4 SRES A1B scenario. An average of 4 future years (2020, 2030, 2040, and 2050) is compared against an average of 2 current years (2001 and 2010). Under this scenario, by the Mid-21st century global air quality is projected to degrade with a global average increase of 2.5 ppb in the maximum 8-hr O3 level and of 0.3 μg m-3 in 24-hr average PM2.5. However, PM2.5 changes are more regional due to regional variations in primary aerosol emissions and emissions of gaseous precursor for secondary PM2.5. Increasing NOx emissions in this scenario combines with a wetter climate elevating levels of OH, HO2, H2O2, and the nitrate radical and increasing the atmosphere's near surface oxidation state. This differs from findings under the RCP scenarios that experience declines in OH from reduced NOx emissions, stratospheric recovery of O3, and increases in CH4 and VOCs. Increasing NOx and O3 levels enhances the nitrogen and O3 deposition, indicating potentially enhanced crop damage and ecosystem stress under this scenario. The enhanced global aerosol level results in enhancements in aerosol optical depth, cloud droplet number concentration, and cloud optical thickness. This leads to dimming at the Earth's surface with a global average reduction in shortwave radiation of 1.2 W m-2. This enhanced dimming leads to a more moderate warming trend and different trends in radiation than those found in NCAR's CCSM simulation, which does not include the advanced chemistry and aerosol treatment of GU-WRF/Chem and cannot simulate the impacts of changing climate and emissions with the same level of detailed

  8. Incidence and predictors of Bone Metastases (BM) and Skeletal-Related Events (SREs) in Small Cell Lung Cancer (SCLC): A Swiss patient cohort

    PubMed Central

    Conen, Katrin; Hagmann, Raphael; Hess, Viviane; Zippelius, Alfred; Rothschild, Sacha I.

    2016-01-01

    Objectives: Bone metastases (BM) and skeletal-related events (SREs) are frequent complications in patients with lung cancer. Whereas in non-small-cell lung cancer (NSCLC) incidence, prognostic impact, and risk factors are well established, there is only little knowledge in patients with small cell lung cancer (SCLC). We retrospectively evaluated the incidence of BM, SRE and their treatment in a SCLC patient cohort treated at our hospital. We further assessed the role of Lactate Dehydrogenase (LDH), a possible predictor of BM development in SCLC patients. Materials and Methods: We retrospectively analyzed patients with the diagnosis of SCLC for BM, SRE, overall treatment patterns, outcome and established prognostic parameters by record review. The prognostic role of LDH was tested using univariate longitudinal regression analysis. Results: We identified 92 consecutive patients with SCLC diagnosed between 2000 and 2010 at our institution. Overall, 36.9% presented with BM at first diagnosis. Median time to BM from first diagnosis was 14.8 months (range) in limited disease (LD) and 0.9 months (range) in extensive disease (ED). The overall incidence of SRE was 18.4%. Only 19.6% of patients with BM were initially treated with bisphosphonates. Conclusions: Elevated LDH, as well as age ≥75 years were independent predictors for BM development in SCLC patients. Although SREs are relevant complications in SCLC, early antiresorptive treatment of BM to reduce the risk of SREs was rare. LDH served as a predictive factor for BM development in our SCLC cohort and therefore should be taken into account in future randomized controlled trials. PMID:27877227

  9. Scenario planning.

    PubMed

    Enzmann, Dieter R; Beauchamp, Norman J; Norbash, Alexander

    2011-03-01

    In facing future developments in health care, scenario planning offers a complementary approach to traditional strategic planning. Whereas traditional strategic planning typically consists of predicting the future at a single point on a chosen time horizon and mapping the preferred plans to address such a future, scenario planning creates stories about multiple likely potential futures on a given time horizon and maps the preferred plans to address the multiple described potential futures. Each scenario is purposefully different and specifically not a consensus worst-case, average, or best-case forecast; nor is scenario planning a process in probabilistic prediction. Scenario planning focuses on high-impact, uncertain driving forces that in the authors' example affect the field of radiology. Uncertainty is the key concept as these forces are mapped onto axes of uncertainty, the poles of which have opposed effects on radiology. One chosen axis was "market focus," with poles of centralized health care (government control) vs a decentralized private market. Another axis was "radiology's business model," with one pole being a unified, single specialty vs a splintered, disaggregated subspecialty. The third axis was "technology and science," with one pole representing technology enabling to radiology vs technology threatening to radiology. Selected poles of these axes were then combined to create 3 scenarios. One scenario, termed "entrepreneurialism," consisted of a decentralized private market, a disaggregated business model, and threatening technology and science. A second scenario, termed "socialized medicine," had a centralized market focus, a unified specialty business model, and enabling technology and science. A third scenario, termed "freefall," had a centralized market focus, a disaggregated business model, and threatening technology and science. These scenarios provide a range of futures that ultimately allow the identification of defined "signposts" that can

  10. Climate change impact and potential adaptation strategies under alternate realizations of climate scenarios for three major crops in Europe

    NASA Astrophysics Data System (ADS)

    Donatelli, Marcello; Srivastava, Amit Kumar; Duveiller, Gregory; Niemeyer, Stefan; Fumagalli, Davide

    2015-07-01

    This study presents an estimate of the effects of climate variables and CO2 on three major crops, namely wheat, rapeseed and sunflower, in EU27 Member States. We also investigated some technical adaptation options which could offset climate change impacts. The time-slices 2000, 2020 and 2030 were chosen to represent the baseline and future climate, respectively. Furthermore, two realizations within the A1B emission scenario proposed by the Special Report on Emissions Scenarios (SRES), from the ECHAM5 and HadCM3 GCM, were selected. A time series of 30 years for each GCM and time slice were used as input weather data for simulation. The time series were generated with a stochastic weather generator trained over GCM-RCM time series (downscaled simulations from the ENSEMBLES project which were statistically bias-corrected prior to the use of the weather generator). GCM-RCM simulations differed primarily for rainfall patterns across Europe, whereas the temperature increase was similar in the time horizons considered. Simulations based on the model CropSyst v. 3 were used to estimate crop responses; CropSyst was re-implemented in the modelling framework BioMA. The results presented in this paper refer to abstraction of crop growth with respect to its production system, and consider growth as limited by weather and soil water. How crop growth responds to CO2 concentrations; pests, diseases, and nutrients limitations were not accounted for in simulations. The results show primarily that different realization of the emission scenario lead to noticeably different crop performance projections in the same time slice. Simple adaptation techniques such as changing sowing dates and the use of different varieties, the latter in terms of duration of the crop cycle, may be effective in alleviating the adverse effects of climate change in most areas, although response to best adaptation (within the techniques tested) differed across crops. Although a negative impact of climate

  11. A future without health? Health dimension in global scenario studies.

    PubMed Central

    Martens, Pim; Huynen, Maud

    2003-01-01

    This paper reviews the health dimension and sociocultural, economic, and ecological determinants of health in existing global scenario studies. Not even half of the 31 scenarios reviewed gave a good description of future health developments and the different scenario studies did not handle health in a consistent way. Most of the global driving forces of health are addressed adequately in the selected scenarios, however, and it therefore would have been possible to describe the future developments in health as an outcome of these multiple driving forces. To provide examples on how future health can be incorporated in existing scenarios, we linked the sociocultural, economic, and environmental developments described in three sets of scenarios (special report on emission scenarios (SRES), global environmental outlook-3 (GEO3), and world water scenarios (WWS)) to three potential, but imaginary, health futures ("age of emerging infectious diseases", "age of medical technology", and "age of sustained health"). This paper provides useful insights into how to deal with future health in scenarios and shows that a comprehensive picture of future health evolves when all important driving forces and pressures are taken into account. PMID:14997242

  12. Contribution of Organic Anion-Transporting Polypeptides 1A/1B to Doxorubicin Uptake and Clearance.

    PubMed

    Lee, Hannah H; Leake, Brenda F; Kim, Richard B; Ho, Richard H

    2017-01-01

    The organic anion-transporting polypeptides represent an important family of drug uptake transporters that mediate the cellular uptake of a broad range of substrates including numerous drugs. Doxorubicin is a highly efficacious and well-established anthracycline chemotherapeutic agent commonly used in the treatment of a wide range of cancers. Although doxorubicin is a known substrate for efflux transporters such as P-glycoprotein (P-gp; MDR1, ABCB1), significantly less is known regarding its interactions with drug uptake transporters. Here, we investigated the role of organic anion transporting polypeptide (OATP) transporters to the disposition of doxorubicin. A recombinant vaccinia-based method for expressing uptake transporters in HeLa cells revealed that OATP1A2, but not OATP1B1 or OATP1B3, and the rat ortholog Oatp1a4 were capable of significant doxorubicin uptake. Interestingly, transwell assays using Madin-Darby canine kidney II cell line cells stably expressing specific uptake and/or efflux transporters revealed that OATP1B1, OATP1B3, and OATP1A2, either alone or in combination with MDR1, significantly transported doxorubicin. An assessment of polymorphisms in SLCO1A2 revealed that four variants were associated with significantly impaired doxorubicin transport in vitro. In vivo doxorubicin disposition studies revealed that doxorubicin plasma area under the curve was significantly higher (1.7-fold) in Slco1a/1b(-/-) versus wild-type mice. The liver-to-plasma ratio of doxorubicin was significantly decreased (2.3-fold) in Slco1a/1b2(-/-) mice and clearance was reduced by 40% compared with wild-type mice, suggesting Oatp1b transporters are important for doxorubicin hepatic uptake. In conclusion, we demonstrate important roles for OATP1A/1B in transporter-mediated uptake and disposition of doxorubicin. Copyright © 2016 by The American Society for Pharmacology and Experimental Therapeutics.

  13. Dispersed fluorescence spectroscopy of the CBr2A1B1-X1A1 transition.

    PubMed

    Hsu, Hui-Ju; Chang, Wei-Zhong; Chang, Bor-Chen

    2005-06-21

    Dispersed fluorescence spectra following the excitation of the CBr2A1B1-X1A1 2 and 2 bands at visible wavelengths were acquired in a discharge supersonic free jet expansion using an intensified charge-coupled device (ICCD) detector. The dispersed fluorescence spectra show signal-to-noise ratios of up to 60 and extend out to a maximum red shift frequency of 6000 cm(-1). Complete and detailed vibrational structure of the ground singlet state (X1A1) was observed. Vibrational parameters including fundamental frequencies, anharmonicities, and coupling constants were determined for the CBr2 X1A1 state. Additional vibrational structure starting at approximately 3650 cm(-1) was observed and this indicates the singlet-triplet energy gap to be >10 kcal mol(-1).

  14. Downscaling climate change scenarios in an urban land use change model.

    PubMed

    Solecki, William D; Oliveri, Charles

    2004-08-01

    The objective of this paper is to describe the process through which climate change scenarios were downscaled in an urban land use model and the results of this experimentation. The land use models (Urban Growth Model [UGM] and the Land Cover Deltatron Model [LCDM]) utilized in the project are part of the SLEUTH program which uses a probabilistic cellular automata protocol. The land use change scenario experiments were developed for the 31-county New York Metropolitan Region (NYMR) of the US Mid-Atlantic Region. The Intergovernmental Panel on Climate Change (IPCC), regional greenhouse gas (GHG) emissions scenarios (Special Report on Emissions Scenarios (SRES) A2 and B2 scenarios) were used to define the narrative scenario conditions of future land use change. The specific research objectives of the land use modeling work involving the SLEUTH program were threefold: (1) Define the projected conversion probabilities and the amount of rural-to-urban land use change for the NYMR as derived by the UGM and LCDM for the years 2020 and 2050, as defined by the pattern of growth for the years 1960-1990; (2) Down-scale the IPCC SRES A2 and B2 scenarios as a narrative that could be translated into alternative growth projections; and, (3) Create two alternative future growth scenarios: A2 scenario which will be associated with more rapid land conversion than found in initial projections, and a B2 scenario which will be associated with a slower level of land conversion. The results of the modeling experiments successfully illustrate the spectrum of possible land use/land cover change scenarios for the years 2020 and 2050. The application of these results into the broader scale climate and health impact study is discussed, as is the general role of land use/land cover change models in climate change studies and associated environmental management strategies.

  15. Toxicokinetic and genomic analysis of chronic arsenic exposure in multidrug-resistance mdr1a/1b(-/-) double knockout mice.

    PubMed

    Xie, Yaxiong; Liu, Jie; Liu, Yaping; Klaassen, Curtis D; Waalkes, Michael P

    2004-01-01

    Multidrug-resistance gene knockout mdr1a/1b(-/-) mice, which are deficient in P-glycoproteins, are more sensitive than wild-type (WT) mice to acute arsenic toxicity. This study assessed toxic manifestations of chronic oral arsenic in mdr1a/1b(-/-) mice, including oxidative stress and altered gene expression, and investigated altered toxicokinetics as a potential basis of enhanced arsenic toxicity. Thus, mdr1a/1b(-/-) and WT mice were exposed to sodium arsenite (0-80 ppm as arsenic) in the drinking water for 10 weeks at which time hepatic arsenic accumulation, lipid peroxidation (LPO), redox status and change in gene expression level were assessed. All mice survived the arsenic exposure, but body weight gain in the highest dose group was reduced in both mdr1a/1b(-/-) and WT mice. Arsenic induced pathological changes, elevated LPO levels and enhanced glutathione S-transferase (GST) activity, in the liver to a greater extent in mdr1a/1b(-/-) than in WT mice. Arsenic also decreased Cu/Zn superoxide dismutase activity in both mdr1a/1b(-/-) and WT mice. The expressions of certain genes, such as those encoding cell proliferation, GST, acute-phase proteins and metabolic enzymes, were modestly altered in arsenic-exposed mice. The expression of cyclin D1, a potential hepatic oncogene, was enhanced in arsenic-exposed mdr1a/1b(-/-) mice only. At the highest level of exposure, hepatic arsenic content was higher in mdr1a/1b(-/-) than in WT mice, suggesting that enhanced accumulation due to transport deficiency may, in part, account for the enhanced toxicity in these mice. In summary, this study shows that chronic arsenic toxicity, including liver pathology and oxidative stress, is enhanced in mdr1a/1b(-/-) mice, possibly due to enhanced accumulation of arsenic as a result of transport system deficiency.

  16. Sudden Bilateral Sensorineural Hearing Loss Associated with HLA A1-B8-DR3 Haplotype

    PubMed Central

    Psillas, G.; Daniilidis, M.; Gerofotis, A.; Veros, K.; Vasilaki, A.; Vital, I.; Markou, K.

    2013-01-01

    Sudden sensorineural hearing loss may be present as a symptom in systemic autoimmune diseases or may occur as a primary disorder without another organ involvement (autoimmune inner ear disease). The diagnosis of autoimmune inner ear disease is still predicated on clinical features, and to date specific diagnostic tests are not available. We report a case of bilateral sudden hearing loss, tinnitus, intense rotatory vertigo, and nausea in a female patient in which the clinical manifestations, in addition to raised levels of circulating immune complexes, antithyroglobulin antibodies, and the presence of the HLA A1-B8-DR3 haplotype, allowed us to hypothesize an autoimmune inner ear disease. Cyclosporine-A immunosuppressive treatment in addition to steroids helped in hearing recovery that occurred progressively with normalization of the hearing function after a five-month treatment. Cyclosporine-A could be proposed as a therapeutic option in case of autoimmune inner ear disease allowing the suspension of corticosteroids that, at high dose, expose patients to potentially serious adverse events. PMID:24106629

  17. Sudden Bilateral Sensorineural Hearing Loss Associated with HLA A1-B8-DR3 Haplotype.

    PubMed

    Psillas, G; Daniilidis, M; Gerofotis, A; Veros, K; Vasilaki, A; Vital, I; Markou, K

    2013-01-01

    Sudden sensorineural hearing loss may be present as a symptom in systemic autoimmune diseases or may occur as a primary disorder without another organ involvement (autoimmune inner ear disease). The diagnosis of autoimmune inner ear disease is still predicated on clinical features, and to date specific diagnostic tests are not available. We report a case of bilateral sudden hearing loss, tinnitus, intense rotatory vertigo, and nausea in a female patient in which the clinical manifestations, in addition to raised levels of circulating immune complexes, antithyroglobulin antibodies, and the presence of the HLA A1-B8-DR3 haplotype, allowed us to hypothesize an autoimmune inner ear disease. Cyclosporine-A immunosuppressive treatment in addition to steroids helped in hearing recovery that occurred progressively with normalization of the hearing function after a five-month treatment. Cyclosporine-A could be proposed as a therapeutic option in case of autoimmune inner ear disease allowing the suspension of corticosteroids that, at high dose, expose patients to potentially serious adverse events.

  18. Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice

    PubMed Central

    Nishio, Miki; Hamada, Koichi; Kawahara, Kohichi; Sasaki, Masato; Noguchi, Fumihito; Chiba, Shuhei; Mizuno, Kensaku; Suzuki, Satoshi O.; Dong, Youyi; Tokuda, Masaaki; Morikawa, Takumi; Hikasa, Hiroki; Eggenschwiler, Jonathan; Yabuta, Norikazu; Nojima, Hiroshi; Nakagawa, Kentaro; Hata, Yutaka; Nishina, Hiroshi; Mimori, Koshi; Mori, Masaki; Sasaki, Takehiko; Mak, Tak W.; Nakano, Toru; Itami, Satoshi; Suzuki, Akira

    2012-01-01

    Mps one binder 1a (MOB1A) and MOB1B are key components of the Hippo signaling pathway and are mutated or inactivated in many human cancers. Here we show that intact Mob1a or Mob1b is essential for murine embryogenesis and that loss of the remaining WT Mob1 allele in Mob1aΔ/Δ1btr/+ or Mob1aΔ/+1btr/tr mice results in tumor development. Because most of these cancers resembled trichilemmal carcinomas, we generated double-mutant mice bearing tamoxifen-inducible, keratinocyte-specific homozygous-null mutations of Mob1a and Mob1b (kDKO mice). kDKO mice showed hyperplastic keratinocyte progenitors and defective keratinocyte terminal differentiation and soon died of malnutrition. kDKO keratinocytes exhibited hyperproliferation, apoptotic resistance, impaired contact inhibition, enhanced progenitor self renewal, and increased centrosomes. Examination of Hippo pathway signaling in kDKO keratinocytes revealed that loss of Mob1a/b altered the activities of the downstream Hippo mediators LATS and YAP1. Similarly, YAP1 was activated in some human trichilemmal carcinomas, and some of these also exhibited MOB1A/1B inactivation. Our results clearly demonstrate that MOB1A and MOB1B have overlapping functions in skin homeostasis, and exert their roles as tumor suppressors by regulating downstream elements of the Hippo pathway. PMID:23143302

  19. Distribution of fluorescence decay times for 1-anilinonaphthalene-8-sulfonate in human oxyhemoglobin A1b solution

    NASA Astrophysics Data System (ADS)

    Drazdou, A. S.; Sobchuk, A. N.; Syakhovich, V. E.; Bokut, O. S.; Kvasyuk, E. I.; Bushuk, B. A.; Bokut, S. B.

    2012-07-01

    We have studied complex formation between molecules of the fluorescent probe 1-anilinonaphthalene-8-sulfonate (1,8-ANS) and the major form (A1) and a minor form (Ab) of hemoglobin. The contribution of the longlived component f3 to the kinetic curves for fluorescence decay in HbA1b solutions is 0.021-0.036, which indicates a dramatic decrease (compared with HbA1) in the accessibility of the central cavity of HbA1b for binding 1,8-ANS. Disappearance of the long-lived component f3 in the fluorescence decay kinetics of 1,8-ANS in HbA1b solutions in the presence of inositol hexaphosphate (IHP) suggests that the regulatory region of HbA1b is completely inaccessible for interaction both with the negatively charged molecules of the probe and with natural regulators of the transport function for this form of the heme protein.

  20. Global Food Demand Scenarios for the 21st Century.

    PubMed

    Bodirsky, Benjamin Leon; Rolinski, Susanne; Biewald, Anne; Weindl, Isabelle; Popp, Alexander; Lotze-Campen, Hermann

    2015-01-01

    Long-term food demand scenarios are an important tool for studying global food security and for analysing the environmental impacts of agriculture. We provide a simple and transparent method to create scenarios for future plant-based and animal-based calorie demand, using time-dependent regression models between calorie demand and income. The scenarios can be customized to a specific storyline by using different input data for gross domestic product (GDP) and population projections and by assuming different functional forms of the regressions. Our results confirm that total calorie demand increases with income, but we also found a non-income related positive time-trend. The share of animal-based calories is estimated to rise strongly with income for low-income groups. For high income groups, two ambiguous relations between income and the share of animal-based products are consistent with historical data: First, a positive relation with a strong negative time-trend and second a negative relation with a slight negative time-trend. The fits of our regressions are highly significant and our results compare well to other food demand estimates. The method is exemplarily used to construct four food demand scenarios until the year 2100 based on the storylines of the IPCC Special Report on Emissions Scenarios (SRES). We find in all scenarios a strong increase of global food demand until 2050 with an increasing share of animal-based products, especially in developing countries.

  1. Global Food Demand Scenarios for the 21st Century

    PubMed Central

    Biewald, Anne; Weindl, Isabelle; Popp, Alexander; Lotze-Campen, Hermann

    2015-01-01

    Long-term food demand scenarios are an important tool for studying global food security and for analysing the environmental impacts of agriculture. We provide a simple and transparent method to create scenarios for future plant-based and animal-based calorie demand, using time-dependent regression models between calorie demand and income. The scenarios can be customized to a specific storyline by using different input data for gross domestic product (GDP) and population projections and by assuming different functional forms of the regressions. Our results confirm that total calorie demand increases with income, but we also found a non-income related positive time-trend. The share of animal-based calories is estimated to rise strongly with income for low-income groups. For high income groups, two ambiguous relations between income and the share of animal-based products are consistent with historical data: First, a positive relation with a strong negative time-trend and second a negative relation with a slight negative time-trend. The fits of our regressions are highly significant and our results compare well to other food demand estimates. The method is exemplarily used to construct four food demand scenarios until the year 2100 based on the storylines of the IPCC Special Report on Emissions Scenarios (SRES). We find in all scenarios a strong increase of global food demand until 2050 with an increasing share of animal-based products, especially in developing countries. PMID:26536124

  2. Evaluation of group A1B erythrocytes converted to type as group O: studies of markers of function and compatibility

    PubMed Central

    Gao, Hong-Wei; Zhuo, Hai-Long; Zhang, Xue; Ji, Shou-Ping; Tan, Ying-Xia; Li, Su-Bo; Jia, Yan-Jun; Xu, Hua; Wu, Qing-Fa; Yun, Zhi-Min; Luo, Qun; Gong, Feng

    2016-01-01

    Background Enzymatic conversion of blood group A1B red blood cells (RBC) to group O RBC (ECO) was achieved by combined treatment with α-galactosidase and α-N-acetylgalactosaminidase. The aim of this study was to evaluate the function and safety of these A1B-ECO RBC in vitro. Materials and methods A 20% packed volume of A1B RBC was treated with enzymes in 250 mM glycine buffer, pH 6.8. The efficiency of the conversion of A and B antigen was evaluated by traditional typing in test tubes, gel column agglutination technology and fluorescence-activated cell sorting (FACS) analysis. The physiological and metabolic parameters of native and ECO RBC were compared, including osmotic fragility, erythrocyte deformation index, levels of 2,3-diphosphoglycerate, ATP, methaemoglobin, free Na+, and free K+. The morphology of native and ECO RBC was observed by scanning electron microscopy. Residual α-galactosidase or α-N-acetylgalactosaminidase in A1B-ECO RBC was detected by double-antibody sandwich ELISA method. Manual cross-matching was applied to ensure blood compatibility. Results The RBC agglutination tests and FACS results showed that A1B RBC were efficiently converted to O RBC. Functional analysis suggested that the conversion process had little impact on the physiological and metabolic parameters of the RBC. The residual amounts of either α-galactosidase or α-N-acetylgalactosaminidase in the A1B-ECO RBC were less than 10 ng/mL of packed RBC. About 18% of group B and 55% of group O sera reacted with the A1B-ECO RBC in a sensitive gel column cross-matching test. Discussion The conversion process does not appear to affect the morphological, physiological or metabolic parameters of A1B-ECO RBC. However, the A1B-ECO RBC still reacted with some antigens. More research on group O and B sera, which may partly reflect the complexity of group A1 the safety of A1B-ECO RBC is necessary before the application of these RBC in clinical transfusion. PMID:26509826

  3. High-resolution interpolation of climate scenarios for Canada derived from general circulation model simulations

    Treesearch

    D. T. Price; D. W. McKenney; L. A. Joyce; R. M. Siltanen; P. Papadopol; K. Lawrence

    2011-01-01

    Projections of future climate were selected for four well-established general circulation models (GCMs) forced by each of three greenhouse gas (GHG) emissions scenarios recommended by the Intergovernmental Panel on Climate Change (IPCC), namely scenarios A2, A1B, and B1 of the IPCC Special Report on Emissions Scenarios. Monthly data for the period 1961-2100 were...

  4. High-resolution prediction of leaf onset date in Japan in the 21st century under the IPCC A1B scenario.

    PubMed

    Hadano, Mayumi; Nasahara, Kenlo Nishida; Motohka, Takeshi; Noda, Hibiki Muraoka; Murakami, Kazutaka; Hosaka, Masahiro

    2013-06-01

    Reports indicate that leaf onset (leaf flush) of deciduous trees in cool-temperate ecosystems is occurring earlier in the spring in response to global warming. In this study, we created two types of phenology models, one driven only by warmth (spring warming [SW] model) and another driven by both warmth and winter chilling (parallel chill [PC] model), to predict such phenomena in the Japanese Islands at high spatial resolution (500 m). We calibrated these models using leaf onset dates derived from satellite data (Terra/MODIS) and in situ temperature data derived from a dense network of ground stations Automated Meteorological Data Acquisition System. We ran the model using future climate predictions created by the Japanese Meteorological Agency's MRI-AGCM3.1S model. In comparison to the first decade of the 2000s, our results predict that the date of leaf onset in the 2030s will advance by an average of 12 days under the SW model and 7 days under the PC model throughout the study area. The date of onset in the 2090s will advance by 26 days under the SW model and by 15 days under the PC model. The greatest impact will occur on Hokkaido (the northernmost island) and in the central mountains.

  5. High-resolution prediction of leaf onset date in Japan in the 21st century under the IPCC A1B scenario

    PubMed Central

    Hadano, Mayumi; Nasahara, Kenlo Nishida; Motohka, Takeshi; Noda, Hibiki Muraoka; Murakami, Kazutaka; Hosaka, Masahiro

    2013-01-01

    Reports indicate that leaf onset (leaf flush) of deciduous trees in cool-temperate ecosystems is occurring earlier in the spring in response to global warming. In this study, we created two types of phenology models, one driven only by warmth (spring warming [SW] model) and another driven by both warmth and winter chilling (parallel chill [PC] model), to predict such phenomena in the Japanese Islands at high spatial resolution (500 m). We calibrated these models using leaf onset dates derived from satellite data (Terra/MODIS) and in situ temperature data derived from a dense network of ground stations Automated Meteorological Data Acquisition System. We ran the model using future climate predictions created by the Japanese Meteorological Agency's MRI-AGCM3.1S model. In comparison to the first decade of the 2000s, our results predict that the date of leaf onset in the 2030s will advance by an average of 12 days under the SW model and 7 days under the PC model throughout the study area. The date of onset in the 2090s will advance by 26 days under the SW model and by 15 days under the PC model. The greatest impact will occur on Hokkaido (the northernmost island) and in the central mountains. PMID:23789086

  6. Development of regional future climate change scenarios in South America using the Eta CPTEC/HadCM3 climate change projections: climatology and regional analyses for the Amazon, São Francisco and the Paraná River basins

    NASA Astrophysics Data System (ADS)

    Marengo, Jose A.; Chou, Sin Chan; Kay, Gillian; Alves, Lincoln M.; Pesquero, José F.; Soares, Wagner R.; Santos, Daniel C.; Lyra, André A.; Sueiro, Gustavo; Betts, Richard; Chagas, Diego J.; Gomes, Jorge L.; Bustamante, Josiane F.; Tavares, Priscila

    2012-05-01

    The objective of this study is to assess the climate projections over South America using the Eta-CPTEC regional model driven by four members of an ensemble of the Met Office Hadley Centre Global Coupled climate model HadCM3. The global model ensemble was run over the twenty-first century according to the SRES A1B emissions scenario, but with each member having a different climate sensitivity. The four members selected to drive the Eta-CPTEC model span the sensitivity range in the global model ensemble. The Eta-CPTEC model nested in these lateral boundary conditions was configured with a 40-km grid size and was run over 1961-1990 to represent baseline climate, and 2011-2100 to simulate possible future changes. Results presented here focus on austral summer and winter climate of 2011-2040, 2041-2070 and 2071-2100 periods, for South America and for three major river basins in Brazil. Projections of changes in upper and low-level circulation and the mean sea level pressure (SLP) fields simulate a pattern of weakening of the tropical circulation and strengthening of the subtropical circulation, marked by intensification at the surface of the Chaco Low and the subtropical highs. Strong warming (4-6°C) of continental South America increases the temperature gradient between continental South America and the South Atlantic. This leads to stronger SLP gradients between continent and oceans, and to changes in moisture transport and rainfall. Large rainfall reductions are simulated in Amazonia and Northeast Brazil (reaching up to 40%), and rainfall increases around the northern coast of Peru and Ecuador and in southeastern South America, reaching up to 30% in northern Argentina. All changes are more intense after 2040. The Precipitation-Evaporation (P-E) difference in the A1B downscaled scenario suggest water deficits and river runoff reductions in the eastern Amazon and São Francisco Basin, making these regions susceptible to drier conditions and droughts in the future.

  7. 26 CFR 1.404(a)-5 - Pension and annuity plans; limitations under section 404(a)(1)(B).

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 5 2010-04-01 2010-04-01 false Pension and annuity plans; limitations under... OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Pension, Profit-Sharing, Stock Bonus Plans, Etc. § 1.404(a)-5 Pension and annuity plans; limitations under section 404(a)(1)(B). (a) Subject...

  8. Flood monitoring and damage assessment in Thailand using multi-temporal HJ-1A/1B and MODIS images

    NASA Astrophysics Data System (ADS)

    Zhou, S. L.; Zhang, W. C.

    2017-02-01

    Flood is one of the most serious natural disasters in South Asia. How to monitor floods and assess damage caused is the most urgent problem for the government and disaster experts. With the advances of remote sensing, images acquired before the beginning of disaster to the very end or after the disaster from Earth-observing satellites benefit the decision making for reduction and protection of disaster dramatically. By using multi-temporal HJ-1A/1B and MODIS remote sensing data, applicability of different algorithms for flood monitoring and damage assessing was investigated in 2011 Thailand floods. Three different algorithms were adopted to monitor flood disaster events with water indices. Comparisons on the flood disaster monitoring and damage assessing by means of HJ-1A/1B and MODIS images suggested that multi-temporal HJ-1A/1B is much useful for the purpose, which demonstrated with the analysis of the thresholds estimated and problems in data post-processing. The variations of the inundated areas in the process of 2011 Thailand floods revealed were presented in this paper, and the damage caused by flooding was evaluated in three aspects, the population in the inundated region, the inundated information of different provinces and land use areas. Compared with MODIS, HJ-1A/1B images can provide more rapid and accurate flood extent and damage assessment for the disaster prevention, damage mitigation and disaster relief.

  9. Evaluation of LLTR Series II tests A-1A and A-1B test results. [Large Leak Test Rig

    SciTech Connect

    Shoopak, B F; Amos, J C; Norvell, T J

    1980-03-01

    The standard methodology, with minor modifications provides conservative yet realistic predictions of leaksite and other sodium system pressures in the LLTR Series II vessel and piping. The good agreement between predicted and measured pressures indicates that the TRANSWRAP/RELAP modeling developed from the Series I tests is applicable to larger scale units prototypical of the Clinch River steam generator design. Calculated sodium system pressures are sensitive to several modeling parameters including rupture disc modeling, acoustic velocity in the test vessel, and flow rate from the rupture tube. The acoustic velocity which produced best agreement with leaksite pressures was calculated based on the shroud diameter and shroud wall thickness. The corresponding rupture tube discharge coefficient was that of the standard design methodology developed from Series I testing. As found in Series I testing, the Series II data suggests that the leading edge of the flow in the relief line is two phase for a single, doubled-ended guillotine tube rupture. The steam generator shroud acts as if it is relatively transparent to the transmission of radial pressures to the vessel wall. Slightly lower sodium system maximum pressures measured during Test A-1b compared to Test A-1a are attributed to premature failure (failure at a lower pressure) of the rupture disc in contact with the sodium for test A-1b. The delay in failure of the second disc in Test A-1b, which was successfully modeled with TRANSWRAP, is attributed to the limited energy in the nitrogen injection.

  10. mir-181a-1/b-1 Modulates Tolerance through Opposing Activities in Selection and Peripheral T Cell Function.

    PubMed

    Schaffert, Steven A; Loh, Christina; Wang, Song; Arnold, Christopher P; Axtell, Robert C; Newell, Evan W; Nolan, Garry; Ansel, K Mark; Davis, Mark M; Steinman, Lawrence; Chen, Chang-Zheng

    2015-08-15

    Understanding the consequences of tuning TCR signaling on selection, peripheral T cell function, and tolerance in the context of native TCR repertoires may provide insight into the physiological control of tolerance. In this study, we show that genetic ablation of a natural tuner of TCR signaling, mir-181a-1/b-1, in double-positive thymocytes dampened TCR and Erk signaling and increased the threshold of positive selection. Whereas mir-181a-1/b-1 deletion in mice resulted in an increase in the intrinsic reactivity of naive T cells to self-antigens, it did not cause spontaneous autoimmunity. Loss of mir-181a-1/b-1 dampened the induction of experimental autoimmune encephalomyelitis and reduced basal TCR signaling in peripheral T cells and their migration from lymph nodes to pathogenic sites. Taken together, these results demonstrate that tolerance can be modulated by microRNA gene products through the control of opposing activities in T cell selection and peripheral T cell function. Copyright © 2015 by The American Association of Immunologists, Inc.

  11. Climate change and coastal vulnerability assessment: Scenarios for integrated assessment

    USGS Publications Warehouse

    Nicholls, R.J.; Wong, P.P.; Burkett, V.; Woodroffe, C.D.; Hay, J.

    2008-01-01

    Coastal vulnerability assessments still focus mainly on sea-level rise, with less attention paid to other dimensions of climate change. The influence of non-climatic environmental change or socio-economic change is even less considered, and is often completely ignored. Given that the profound coastal changes of the twentieth century are likely to continue through the twenty-first century, this is a major omission, which may overstate the importance of climate change, and may also miss significant interactions of climate change with other non-climate drivers. To better support climate and coastal management policy development, more integrated assessments of climatic change in coastal areas are required, including the significant non-climatic changes. This paper explores the development of relevant climate and non-climate drivers, with an emphasis on the non-climate drivers. While these issues are applicable within any scenario framework, our ideas are illustrated using the widely used SRES scenarios, with both impacts and adaptation being considered. Importantly, scenario development is a process, and the assumptions that are made about future conditions concerning the coast need to be explicit, transparent and open to scientific debate concerning their realism and likelihood. These issues are generic across other sectors. ?? Integrated Research System for Sustainability Science and Springer 2008.

  12. Sea of Scenarios: Reducing Uncertainties in Methane Projections

    NASA Astrophysics Data System (ADS)

    Matthews, E.; Baum, E.

    2010-12-01

    Climate-chemistry model experiments for the 21st century have relied almost exclusively on a small set of unexamined methane (and other) emission projections from economics-based models. Over the past decade, the US Environmental Protection Agency and the International Institute of Applied Systems Analysis (IIASA) provided baseline and mitigation methane scenarios. The SRES family of projections for the IPCC Third Assessment Report (2001) encompassed multiple economic, demographic, and environmental assumptions quantified by several models. In contrast to both of these efforts, plans for IPCC5 include additional scenario development consistent with end-of-century forcings ranging from 2.6 to 8.5W/m2. The largely black-box nature of emission projections used in climate-chemistry experiments and policy analyses has received little attention despite the substantial influence these inputs can exert. This lack of transparency makes assessing the likelihood, or even the plausibility, of projected emissions difficult, contributes to uncertainties in climate simulations, and leaves policy discussions lacking the practical understanding needed to decide on mitigation strategies. We report on analysis of multiple baseline and mitigation methane projections, including our own new ones, to assess the plausibility of underlying assumptions and data. We propose that this analysis can reduce uncertainties in climate predictions by restricting, not enlarging, the suite of methane scenarios to those likely to occur.

  13. Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice

    PubMed Central

    Nishio, Miki; Sugimachi, Keishi; Goto, Hiroki; Wang, Jia; Morikawa, Takumi; Miyachi, Yosuke; Takano, Yusuke; Hikasa, Hiroki; Itoh, Tohru; Suzuki, Satoshi O.; Kurihara, Hiroki; Aishima, Shinichi; Leask, Andrew; Sasaki, Takehiko; Nakano, Toru; Nishina, Hiroshi; Nishikawa, Yuji; Sekido, Yoshitaka; Nakao, Kazuwa; Shin-ya, Kazuo; Mimori, Koshi; Suzuki, Akira

    2016-01-01

    Mps One Binder Kinase Activator (MOB)1A/1B are core components of the Hippo pathway that coactivate large tumor suppressor homolog (LATS) kinases. Mob1a/1b double deficiency in mouse liver (LMob1DKO) results in hyperplasia of oval cells and immature cholangiocytes accompanied by inflammatory cell infiltration and fibrosis. More than half of mutant mice die within 3 wk of birth. All survivors eventually develop liver cancers, particularly combined hepatocellular and cholangiocarcinomas (cHC-CCs) and intrahepatic cholangiocellular carcinomas (ICCs), and die by age 60 wk. Because this phenotype is the most severe among mutant mice lacking a Hippo signaling component, MOB1A/1B constitute the critical hub of Hippo signaling in mammalian liver. LMob1DKO liver cells show hyperproliferation, increased cell saturation density, hepatocyte dedifferentiation, enhanced epithelial–mesenchymal transition and cell migration, and elevated transforming growth factor beta(TGF-β)2/3 production. These changes are strongly dependent on Yes-Associated Protein-1 (Yap1) and partially dependent on PDZ-binding motif (Taz) and Tgfbr2, but independent of connective tissue growth factor (Ctgf). In human liver cancers, YAP1 activation is frequent in cHC-CCs and ICCs and correlates with SMAD family member 2 activation. Drug screening revealed that antiparasitic macrocyclic lactones inhibit YAP1 activation in vitro and in vivo. Targeting YAP1/TAZ with these drugs in combination with inhibition of the TGF-β pathway may be effective treatment for cHC-CCs and ICCs. PMID:26699479

  14. Transgenic (cyp19a1b-GFP) zebrafish embryos as a tool for assessing combined effects of oestrogenic chemicals.

    PubMed

    Petersen, Karina; Fetter, Eva; Kah, Olivier; Brion, François; Scholz, Stefan; Tollefsen, Knut Erik

    2013-08-15

    Endocrine disrupting chemicals and especially oestrogen receptor (ER) agonists have been extensively studied over the years due to their potential effects on sexual development and reproduction in vertebrates, notably fish. As ER agonists can exist as complex mixtures in the aquatic environment, evaluating the impact of combined exposure on oestrogenic effects has become increasingly important. Use of predictive models such as concentration addition (CA) and independent action (IA) has allowed assessment of combined estrogenic effects of complex multi-compound mixtures of ER agonists in various fish in vitro and in vivo experimental models. The present work makes use of a transgenic zebrafish strain, tg(cyp19a1b-GFP), which expresses the green fluorescent protein (GFP) under the control of the cyp19a1b (brain aromatase or aromatase B) gene to determine the oestrogenic potency of ER agonists alone or in mixtures. In these studies, tg(cyp19a1b-GFP) zebrafish embryos were exposed for four days (from one to five days post fertilization) to five different oestrogenic chemicals; 17α-ethinylestradiol (EE2), 17β-estradiol (E2), estrone (E1), bisphenol A (BPA) and 4-tert-octylphenol (OP), and three mixtures of up to four of these compounds. The mixture of BPA, OP and E2 was also tested with primary cultures of rainbow trout hepatocytes by analysing the ER-mediated induction of the oestrogenic biomarker vitellogenin in order to compare the performance of the two methods for assessing oestrogenic effects of complex mixtures. The three tested mixtures were predominantly acting in an additive manner on the expression of GFP. Additivity was indicated by the overlap of the 95% confidence interval of the concentration response curves for the observed data with the CA and IA prediction models, and model deviation ratios within a factor of two for a majority of the mixture concentrations. However, minor deviations determined as more than additive effects for the mixture of EE2, E1

  15. The histone demethylases Jhdm1a/1b enhance somatic cell reprogramming in a vitamin-C-dependent manner.

    PubMed

    Wang, Tao; Chen, Keshi; Zeng, Xiaoming; Yang, Jianguo; Wu, Yun; Shi, Xi; Qin, Baoming; Zeng, Lingwen; Esteban, Miguel Angel; Pan, Guangjin; Pei, Duanqing

    2011-12-02

    Reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) resets the epigenome to an embryonic-like state. Vitamin C enhances the reprogramming process, but the underlying mechanisms are unclear. Here we show that the histone demethylases Jhdm1a/1b are key effectors of somatic cell reprogramming downstream of vitamin C. We first observed that vitamin C induces H3K36me2/3 demethylation in mouse embryonic fibroblasts in culture and during reprogramming. We then identified Jhdm1a/1b, two known vitamin-C-dependent H3K36 demethylases, as potent regulators of reprogramming through gain- and loss-of-function approaches. Furthermore, we found that Jhdm1b accelerates cell cycle progression and suppresses cell senescence during reprogramming by repressing the Ink4/Arf locus. Jhdm1b also cooperates with Oct4 to activate the microRNA cluster 302/367, an integral component of the pluripotency machinery. Our results therefore reveal a role for H3K36me2/3 in cell fate determination and establish a link between histone demethylases and vitamin-C-induced reprogramming.

  16. Screening Estrogenic Activities of Chemicals or Mixtures In Vivo Using Transgenic (cyp19a1b-GFP) Zebrafish Embryos

    PubMed Central

    Brion, François; Le Page, Yann; Piccini, Benjamin; Cardoso, Olivier; Tong, Sok-Keng; Chung, Bon-chu; Kah, Olivier

    2012-01-01

    The tg(cyp19a1b-GFP) transgenic zebrafish expresses GFP (green fluorescent protein) under the control of the cyp19a1b gene, encoding brain aromatase. This gene has two major characteristics: (i) it is only expressed in radial glial progenitors in the brain of fish and (ii) it is exquisitely sensitive to estrogens. Based on these properties, we demonstrate that natural or synthetic hormones (alone or in binary mixture), including androgens or progestagens, and industrial chemicals induce a concentration-dependent GFP expression in radial glial progenitors. As GFP expression can be quantified by in vivo imaging, this model presents a very powerful tool to screen and characterize compounds potentially acting as estrogen mimics either directly or after metabolization by the zebrafish embryo. This study also shows that radial glial cells that act as stem cells are direct targets for a large panel of endocrine disruptors, calling for more attention regarding the impact of environmental estrogens and/or certain pharmaceuticals on brain development. Altogether these data identify this in vivo bioassay as an interesting alternative to detect estrogen mimics in hazard and risk assessment perspective. PMID:22586461

  17. Screening estrogenic activities of chemicals or mixtures in vivo using transgenic (cyp19a1b-GFP) zebrafish embryos.

    PubMed

    Brion, François; Le Page, Yann; Piccini, Benjamin; Cardoso, Olivier; Tong, Sok-Keng; Chung, Bon-chu; Kah, Olivier

    2012-01-01

    The tg(cyp19a1b-GFP) transgenic zebrafish expresses GFP (green fluorescent protein) under the control of the cyp19a1b gene, encoding brain aromatase. This gene has two major characteristics: (i) it is only expressed in radial glial progenitors in the brain of fish and (ii) it is exquisitely sensitive to estrogens. Based on these properties, we demonstrate that natural or synthetic hormones (alone or in binary mixture), including androgens or progestagens, and industrial chemicals induce a concentration-dependent GFP expression in radial glial progenitors. As GFP expression can be quantified by in vivo imaging, this model presents a very powerful tool to screen and characterize compounds potentially acting as estrogen mimics either directly or after metabolization by the zebrafish embryo. This study also shows that radial glial cells that act as stem cells are direct targets for a large panel of endocrine disruptors, calling for more attention regarding the impact of environmental estrogens and/or certain pharmaceuticals on brain development. Altogether these data identify this in vivo bioassay as an interesting alternative to detect estrogen mimics in hazard and risk assessment perspective.

  18. Heterozygous mutation of eEF1A1b resulted in spermatogenesis arrest and infertility in male tilapia, Oreochromis niloticus

    PubMed Central

    Chen, Jinlin; Jiang, Dongneng; Tan, Dejie; Fan, Zheng; Wei, Yingying; Li, Minghui; Wang, Deshou

    2017-01-01

    Eukaryotic elongation factor 1 alpha (eEF1A) is an essential component of the translational apparatus. In the present study, eEF1A1b was isolated from the Nile tilapia. Real-time PCR and Western blot revealed that eEF1A1b was expressed highly in the testis from 90 dah (days after hatching) onwards. In situ hybridization and immunohistochemistry analyses showed that eEF1A1b was highly expressed in the spermatogonia of the testis. CRISPR/Cas9 mediated mutation of eEF1A1b resulted in spermatogenesis arrest and infertility in the F0 XY fish. Consistently, heterozygous mutation of eEF1A1b (eEF1A1b+/−) resulted in an absence of spermatocytes at 90 dah, very few spermatocytes, spermatids and spermatozoa at 180 dah, and decreased Cyp11b2 and serum 11-ketotestosterone level at both stages. Further examination of the fertilization capacity of the sperm indicated that the eEF1A1b+/− XY fish were infertile due to abnormal spermiogenesis. Transcriptomic analyses of the eEF1A1b+/− testis from 180 dah XY fish revealed that key elements involved in spermatogenesis, steroidogenesis and sperm motility were significantly down-regulated compared with the control XY. Transgenic overexpression of eEF1A1b rescued the spermatogenesis arrest phenotype of the eEF1A1b+/− testis. Taken together, our data suggested that eEF1A1b is crucial for spermatogenesis and male fertility in the Nile tilapia. PMID:28266557

  19. Scenarios of land use and land cover change in the conterminous United States: Utilizing the special report on emission scenarios at ecoregional scales

    USGS Publications Warehouse

    Sleeter, Benjamin M.; Sohl, Terry L.; Bouchard, Michelle A.; Reker, Ryan R.; Soulard, Christopher E.; Acevedo, William; Griffith, Glenn E.; Sleeter, Rachel R.; Auch, Roger F.; Sayler, Kristi L.; Prisley, Stephen; Zhu, Zhi-Liang

    2012-01-01

    Global environmental change scenarios have typically provided projections of land use and land cover for a relatively small number of regions or using a relatively coarse resolution spatial grid, and for only a few major sectors. The coarseness of global projections, in both spatial and thematic dimensions, often limits their direct utility at scales useful for environmental management. This paper describes methods to downscale projections of land-use and land-cover change from the Intergovernmental Panel on Climate Change's Special Report on Emission Scenarios to ecological regions of the conterminous United States, using an integrated assessment model, land-use histories, and expert knowledge. Downscaled projections span a wide range of future potential conditions across sixteen land use/land cover sectors and 84 ecological regions, and are logically consistent with both historical measurements and SRES characteristics. Results appear to provide a credible solution for connecting regionalized projections of land use and land cover with existing downscaled climate scenarios, under a common set of scenario-based socioeconomic assumptions.

  20. Successful unintentional ABO-incompatible renal transplantation: Blood group A1B donor into an A2B recipient.

    PubMed

    Fadeyi, Emmanuel A; Stratta, Robert J; Farney, Alan C; Pomper, Gregory J

    2014-05-01

    To report a successful unintentional transplantation of a deceased donor kidney from an "incompatible" A1B donor into a recipient who was blood group A2B with unsuspected preformed anti-A1 antibodies. The donor and recipient were both typed for ABO antigens. The recipient was tested for ABO and non-ABO antibodies. The recipient was typed for HLA class I and class II antigens, including HLA antibody screen. The T-and B-flow cytometry crossmatch test was performed using standard protocol. The donor-recipient pair was a complete six-antigen human leukocyte antigen mismatch, but final T- and B-flow cytometry cross-match tests were compatible. The recipient was a 65-year-old woman with a medical history of end-stage renal disease secondary to diabetic nephropathy who underwent kidney transplantation from a 46-year-old brain-dead standard criteria donor. The recipient's RBCs were negative with A1 lectin, and the recipient was thus typed as an A2 subgroup. Anti-A1 could be demonstrated in the recipient's plasma. The donor's RBCs were positive with A1 lectin, thereby conferring an A1 blood type. It is safe to transplant across the A1/A2 blood group barrier provided that the preformed antibodies are not reactive at 37°C and with anti-human globulin.

  1. Multi-SNP analysis of MHC region: remarkable conservation of HLA-A1-B8-DR3 haplotype.

    PubMed

    Aly, Theresa A; Eller, Elise; Ide, Akane; Gowan, Katherine; Babu, Sunanda R; Erlich, Henry A; Rewers, Marian J; Eisenbarth, George S; Fain, Pamela R

    2006-05-01

    Technology has become available to cost-effectively analyze thousands of single nucleotide polymorphisms (SNPs). We recently confirmed by genotyping a small series of class I alleles and microsatellite markers that the extended haplotype HLA-A1-B8-DR3 (8.1 AH) at the major histocompatibility complex (MHC) is a common and conserved haplotype. To further evaluate the region of conservation of the DR3 haplotypes, we genotyped 31 8.1 AHs and 29 other DR3 haplotypes with a panel of 656 SNPs spanning 4.8 Mb in the MHC region. This multi-SNP evaluation revealed a 2.9-Mb region that was essentially invariable for all 31 8.1 AHs. The 31 8.1 AHs were >99.9% identical for 384 consecutive SNPs of the 656 SNPs analyzed. Future association studies of MHC-linked susceptibility to type 1 diabetes will need to account for the extensive conservation of the 8.1 AH, since individuals who carry this haplotype provide no information about the differential effects of the alleles that are present on this haplotype.

  2. The A1 and A1B proteins of heterogeneous nuclear ribonucleoparticles modulate 5' splice site selection in vivo.

    PubMed Central

    Yang, X; Bani, M R; Lu, S J; Rowan, S; Ben-David, Y; Chabot, B

    1994-01-01

    Recent in vitro results suggest that the heterogeneous nuclear ribonucleoparticle (hnRNP) A1 protein modulates alternative splicing by favoring distal 5' splice site (5'SS) selection and exon skipping. We used a mouse erythroleukemia (MEL) cell line (CB3C7) deficient in the expression of hnRNP A1 to test whether variations in hnRNP A1 and AlB protein levels affected alternative splicing in vivo. In contrast to A1-expressing MEL cell lines, CB3C7 cells preferentially selected the proximal 13S and 12S 5'SS on the adenovirus E1A pre-mRNA. Transiently expressing the A1 or A1B cDNA in CB3C7 cells shifted 5'SS selection toward the more distal 9S donor site. A1 protein synthesis was required for this effect since the expression of a mutated A1 cDNA did not affect 5'SS selection. These results demonstrate that in vivo variations in hnRNP A1 protein levels can influence 5'SS selection. Images PMID:8041722

  3. Future Extreme Heat Scenarios to Enable the Assessment of Climate Impacts on Public Health over the Coterminous U.S

    NASA Astrophysics Data System (ADS)

    Quattrochi, D. A.; Crosson, W. L.; Al-Hamdan, M. Z.; Estes, M. G., Jr.

    2013-12-01

    In the United States, extreme heat is the most deadly weather-related hazard. In the face of a warming climate and urbanization, which contributes to local-scale urban heat islands, it is very likely that extreme heat events (EHEs) will become more common and more severe in the U.S. This research seeks to provide historical and future measures of climate-driven extreme heat events to enable assessments of the impacts of heat on public health over the coterminous U.S. We use atmospheric temperature and humidity information from meteorological reanalysis and from Global Climate Models (GCMs) to provide data on past and future heat events. The focus of research is on providing assessments of the magnitude, frequency and geographic distribution of extreme heat in the U.S. to facilitate public health studies. In our approach, long-term climate change is captured with GCM outputs, and the temporal and spatial characteristics of short-term extremes are represented by the reanalysis data. Two future time horizons for 2040 and 2090 are compared to the recent past period of 1981-2000. We characterize regional-scale temperature and humidity conditions using GCM outputs for two climate change scenarios (A2 and A1B) defined in the Special Report on Emissions Scenarios (SRES). For each future period, 20 years of multi-model GCM outputs are analyzed to develop a ';heat stress climatology' based on statistics of extreme heat indicators. Differences between the two future and the past period are used to define temperature and humidity changes on a monthly time scale and regional spatial scale. These changes are combined with the historical meteorological data, which is hourly and at a spatial scale (12 km) much finer than that of GCMs, to create future climate realizations. From these realizations, we compute the daily heat stress measures and related spatially-specific climatological fields, such as the mean annual number of days above certain thresholds of maximum and minimum air

  4. Future Extreme Heat Scenarios to Enable the Assessment of Climate Impacts on Public Health over the Coterminous U.S.

    NASA Technical Reports Server (NTRS)

    Quattrochi, Dale A.; Crosson, William L.; Al-Hamdan, Mohammad Z.; Estes, Maurice G., Jr.

    2013-01-01

    In the United States, extreme heat is the most deadly weather-related hazard. In the face of a warming climate and urbanization, which contributes to local-scale urban heat islands, it is very likely that extreme heat events (EHEs) will become more common and more severe in the U.S. This research seeks to provide historical and future measures of climate-driven extreme heat events to enable assessments of the impacts of heat on public health over the coterminous U.S. We use atmospheric temperature and humidity information from meteorological reanalysis and from Global Climate Models (GCMs) to provide data on past and future heat events. The focus of research is on providing assessments of the magnitude, frequency and geographic distribution of extreme heat in the U.S. to facilitate public health studies. In our approach, long-term climate change is captured with GCM outputs, and the temporal and spatial characteristics of short-term extremes are represented by the reanalysis data. Two future time horizons for 2040 and 2090 are compared to the recent past period of 1981- 2000. We characterize regional-scale temperature and humidity conditions using GCM outputs for two climate change scenarios (A2 and A1B) defined in the Special Report on Emissions Scenarios (SRES). For each future period, 20 years of multi-model GCM outputs are analyzed to develop a 'heat stress climatology' based on statistics of extreme heat indicators. Differences between the two future and the past period are used to define temperature and humidity changes on a monthly time scale and regional spatial scale. These changes are combined with the historical meteorological data, which is hourly and at a spatial scale (12 km), to create future climate realizations. From these realizations, we compute the daily heat stress measures and related spatially-specific climatological fields, such as the mean annual number of days above certain thresholds of maximum and minimum air temperatures, heat indices

  5. Overview of a new scenario framework for climate change research

    NASA Astrophysics Data System (ADS)

    Ebi, K. L.

    2013-12-01

    The scientific community is developing new integrated global, regional, and sectoral scenarios to facilitate interdisciplinary research and assessment to explore the range of possible future climates and related physical changes; the risks these could pose to human and natural systems, particularly how these changes could interact with social, economic, and environmental development pathways; the degree to which mitigation and adaptation policies can avoid and reduce the risks; the costs and benefits of various policy mixes; residual impacts under alternative pathways; and the relationship with sustainable development. Developing new scenarios for use in impacts, adaptation, and mitigation research requires more than emissions of greenhouse gases and resulting climate change. Scenarios also require assumptions about socioeconomic development, including a narrative, and qualitative and quantitative assumptions about development patterns. An insight recently gained is that the magnitude and extent of greenhouse gas emissions is relatively independent of demographic and socioeconomic development; that is, multiple demographic and socioeconomic development pathways can lead to any particular emission scenario. A relatively wealthy world with high population density could have low greenhouse gas emissions because of policies that encourage energy efficiency and sufficient low emission technology. The opposite also is plausible. Therefore, demographic and socioeconomic development pathways can be described separately from the Representative Concentration Pathways and then combined using a matrix architecture into a broader range of scenarios than was possible with the SRES. Shared Socioeconomic Pathways (SSPs) define the state of human and natural societies at a macro scale. To encompass a wide range of possible development pathways, five SSPs are defined along two axes describing worlds with increasing socioeconomic challenges to mitigation (y-axis) and adaptation (x

  6. Nuclear Security Futures Scenarios.

    SciTech Connect

    Keller, Elizabeth James Kistin; Warren, Drake Edward; Hayden, Nancy Kay; Passell, Howard D.; Malczynski, Leonard A.; Backus, George A.

    2017-01-01

    This report provides an overview of the scenarios used in strategic futures workshops conducted at Sandia on September 21 and 29, 2016. The workshops, designed and facilitated by analysts in Center 100, used scenarios to enable thought leaders to think collectively about the changing aspects of global nuclear security and the potential implications for the US Government and Sandia National Laboratories.

  7. Susceptibilities of Genotype 1a, 1b, and 3 Hepatitis C Virus Variants to the NS5A Inhibitor Elbasvir

    PubMed Central

    Curry, Stephanie; McMonagle, Patricia; Yeh, Wendy W.; Ludmerer, Steven W.; Jumes, Patricia A.; Marshall, William L.; Kong, Stephanie; Ingravallo, Paul; Black, Stuart; Pak, Irene; DiNubile, Mark J.

    2015-01-01

    Elbasvir is an investigational NS5A inhibitor with in vitro activity against multiple HCV genotypes. Antiviral activity of elbasvir was measured in replicons derived from wild-type or resistant variants of genotypes 1a, 1b, and 3. The barrier to resistance was assessed by the number of resistant colonies selected by exposure to various elbasvir concentrations. In a phase 1b dose-escalating study, virologic responses were determined in 48 noncirrhotic adult men with chronic genotype 1 or 3 infections randomized to placebo or elbasvir from 5 to 50 mg (genotype 1) or 10 to 100 mg (genotype 3) once daily for 5 days. The NS5A gene was sequenced from plasma specimens obtained before, during, and after treatment. Elbasvir suppressed the emergence of resistance-associated variants (RAVs) in vitro in a dose-dependent manner. Variants selected by exposure to high elbasvir concentrations typically encoded multiple amino acid substitutions (most commonly involving loci 30, 31, and 93), conferring high-level elbasvir resistance. In the monotherapy study, patients with genotype 1b had greater reductions in HCV RNA levels than patients with genotype 1a at all elbasvir doses; responses in patients with genotype 3 were generally less pronounced than for genotype 1, particularly at lower elbasvir doses. M28T, Q30R, L31V, and Y93H in genotype 1a, L31V and Y93H in genotype 1b, and A30K, L31F, and Y93H in genotype 3 were the predominant RAVs selected by elbasvir monotherapy. Virologic findings in patients were consistent with the preclinical observations. NS5A-RAVs emerged most often at amino acid positions 28, 30, 31, and 93 in both the laboratory and clinical trial. (The MK-8742 P002 trial has been registered at ClinicalTrials.gov under identifier NCT01532973.) PMID:26303801

  8. Exposure scenarios for workers.

    PubMed

    Marquart, Hans; Northage, Christine; Money, Chris

    2007-12-01

    The new European chemicals legislation REACH (Registration, Evaluation, Authorisation and restriction of Chemicals) requires the development of Exposure Scenarios describing the conditions and risk management measures needed for the safe use of chemicals. Such Exposure Scenarios should integrate considerations of both human health and the environment. Specific aspects are relevant for worker exposure. Gathering information on the uses of the chemical is an important step in developing an Exposure Scenario. In-house information at manufacturers is an important source. Downstream users can contribute information through direct contact or through their associations. Relatively simple approaches (Tier 1 tools, such as the ECETOC Targeted Risk Assessment and the model EASE) can be used to develop broad Exposure Scenarios that cover many use situations. These approaches rely on the categorisation of just a few determinants, including only a small number of risk management measures. Such approaches have a limited discriminatory power and are rather conservative. When the hazard of the substance or the complexity of the exposure situation require a more in-depth approach, further development of the Exposure Scenarios with Tier 2 approaches is needed. Measured data sets of worker exposure are very valuable in a Tier 2 approach. Some downstream user associations have attempted to build Exposure Scenarios based on measured data sets. Generic Tier 2 tools for developing Exposure Scenarios do not exist yet. To enable efficient development of the worker exposure part of Exposure Scenarios a further development of Tier 1 and Tier 2 tools is needed. Special attention should be given to user friendliness and to the validity (boundaries) of the approaches. The development of standard worker exposure descriptions or full Exposure Scenarios by downstream user branches in cooperation with manufacturers and importers is recommended.

  9. Mars base buildup scenarios

    SciTech Connect

    Blacic, J.D.

    1985-01-01

    Two surface base build-up scenarios are presented in order to help visualize the mission and to serve as a basis for trade studies. In the first scenario, direct manned landings on the Martian surface occur early in the missions and scientific investigation is the main driver and rationale. In the second scenario, early development of an infrastructure to exploite the volatile resources of the Martian moons for economic purposes is emphasized. Scientific exploration of the surface is delayed at first, but once begun develops rapidly aided by the presence of a permanently manned orbital station.

  10. Haemocoel injection of PirA1B1 to Galleria mellonella larvae leads to disruption of the haemocyte immune functions

    PubMed Central

    Wu, Gongqing; Yi, Yunhong

    2016-01-01

    The bacterium Photorhabdus luminescens produces a number of insecticidal proteins to kill its larval prey. In this study, we cloned the gene coding for a binary toxin PirA1B1 and purified the recombinant protein using affinity chromatography combined with desalination technology. Furthermore, the cytotoxicity of the recombinant protein against the haemocytes of Galleria mellonella larvae was investigated. We found that the protein had haemocoel insecticidal activity against G. mellonella with an LD50 of 131.5 ng/larva. Intrahaemocoelic injection of PirA1B1 into G. mellonella resulted in significant decreases in haemocyte number and phagocytic ability. In in vitro experiments, PirA1B1 inhibited the spreading behaviour of the haemocytes of G. mellonella larvae and even caused haemocyte degeneration. Fluorescence microscope analysis and visualization of haemocyte F-actin stained with phalloidin-FITC showed that the PirA1B1 toxin disrupted the organization of the haemocyte cytoskeleton. Our results demonstrated that the PirA1B1 toxin disarmed the insect cellular immune system. PMID:27734915

  11. Haemocoel injection of PirA1B1 to Galleria mellonella larvae leads to disruption of the haemocyte immune functions.

    PubMed

    Wu, Gongqing; Yi, Yunhong

    2016-10-13

    The bacterium Photorhabdus luminescens produces a number of insecticidal proteins to kill its larval prey. In this study, we cloned the gene coding for a binary toxin PirA1B1 and purified the recombinant protein using affinity chromatography combined with desalination technology. Furthermore, the cytotoxicity of the recombinant protein against the haemocytes of Galleria mellonella larvae was investigated. We found that the protein had haemocoel insecticidal activity against G. mellonella with an LD50 of 131.5 ng/larva. Intrahaemocoelic injection of PirA1B1 into G. mellonella resulted in significant decreases in haemocyte number and phagocytic ability. In in vitro experiments, PirA1B1 inhibited the spreading behaviour of the haemocytes of G. mellonella larvae and even caused haemocyte degeneration. Fluorescence microscope analysis and visualization of haemocyte F-actin stained with phalloidin-FITC showed that the PirA1B1 toxin disrupted the organization of the haemocyte cytoskeleton. Our results demonstrated that the PirA1B1 toxin disarmed the insect cellular immune system.

  12. Beyond Pattern Scaling: Statistical Emulation and its Implications for ScenarioMIP

    NASA Astrophysics Data System (ADS)

    Challenor, P. G.; Williamson, D.

    2014-12-01

    One of the crucial aspects of climate policy in the near future is the design of mitigation strategies. However, we can only get information from state of the art climate models at a handful of mitigation scenarios (e.g. the SRES and RCP scenarios). In order to compare alternative strategies and their impacts using models, we need to consider the climate effects of the corresponding emission/concentration pathways for which we don't have climate model output. Currently this is mainly done by pattern-scaling - multiplying the mean pattern of climate change by the change in the mean of the variable (e.g. temperature or precipitation) over time. A generalised alternative to pattern scaling is statistical emulation. A statistical emulator is a more sophisticated way of interpolating climates between a limited number of model runs. Although widely used in science for the modelling of computer experiments, the use of statistical emulators in climate science has been limited and mainly used for perturbed physics ensembles. However emulators are perfectly well suited for use with forcing conditions instead of (or as well as) model parameters. Pattern scaling is a special (very simple) case of an emulator. We will show how by parameterising the forcing functions and building emulators we can predict the climate for any reasonable set of forcings (including overshoot scenarios and other 'odd' forcing pathways). We also set out how a ScenarioMIP type experiment would have to be configured to achieve this.

  13. GLOBAL ALTERNATIVE FUTURE SCENARIOS

    EPA Science Inventory

    One way to examine possible future outcomes for environmental protection is through the development and analysis of alternative future scenarios. This type of assessment postulates two or more different paths that social and environmental development might take, using correspond...

  14. Emission scenarios: Explaining differences

    NASA Astrophysics Data System (ADS)

    Iyer, Gokul; Edmonds, James

    2017-01-01

    Carbon dioxide emission scenarios rely on a number of assumptions about how societies will develop in the future, creating uncertainty in projections. Now, research reveals the sensitivity of emission estimates to some of these assumptions.

  15. Analysis of Tubulin Alpha-1A/1B C-Terminal Tail Post-translational Poly-glutamylation Reveals Novel Modification Sites

    PubMed Central

    Sahab, Ziad J.; Kirilyuk, Alexander; Zhang, Lihua; Khamis, Zahraa I.; Pompach, Petr; Sung, YouMe; Byers, Stephen W.

    2012-01-01

    Tubulin-α1A/1B C-terminal tail (CTT) has 7 glutamic acid residues among the last 11 amino acids of its sequence that are potential sites for glutamylation. Cleavage of C-terminal tyrosine resulting in the detyrosinated form of tubulin-α1A/1B is another major modification. These modifications among others bring about highly heterogeneous tubulin samples in brain cells and microtubules, play a major role in directing intracellular trafficking, microtubule dynamics, and mitotic events, and can vary depending on the cell and disease state, such as cancer and neurodegenerative disorders. Identified previously using primary mass spectrometry (MS) ions and partial Edman sequencing, tubulin-α1A/1B glutamylation was found exclusively on the E445 residue. We here describe the analysis of tubulin-α1A/1B glutamylation and detyrosination after 2DE separation, trypsin and proteinase K in-gel digestion, and nanoUPLC-ESI-QqTOF-MS/MS of mouse brain and bovine microtubules. Tyrosinated, detyrosinated, and Δ2- tubulin-α1A/1B CTTs were identified based on a comparison of fragmentation patterns and retention times between endogenous and synthetic peptides. Stringent acceptance criteria were adapted for the identification of novel glutamylation sites. In addition to the previously identified site at E445, glutamylation on mouse and bovine tubulin-α1A/1B CTTs was identified on E441 and E443 with MASCOT Expect values below 0.01. O-methylation of glutamates was also observed. PMID:22296162

  16. Analysis of tubulin alpha-1A/1B C-terminal tail post-translational poly-glutamylation reveals novel modification sites.

    PubMed

    Sahab, Ziad J; Kirilyuk, Alexander; Zhang, Lihua; Khamis, Zahraa I; Pompach, Petr; Sung, Youme; Byers, Stephen W

    2012-03-02

    Tubulin-α(1A/1B) C-terminal tail (CTT) has seven glutamic acid residues among the last 11 amino acids of its sequence that are potential sites for glutamylation. Cleavage of C-terminal tyrosine resulting in the detyrosinated form of tubulin-α(1A/1B) is another major modification. These modifications among others bring about highly heterogeneous tubulin samples in brain cells and microtubules, play a major role in directing intracellular trafficking, microtubule dynamics, and mitotic events, and can vary depending on the cell and disease state, such as cancer and neurodegenerative disorders. Identified previously using primary mass spectrometry (MS) ions and partial Edman sequencing, tubulin-α(1A/1B) glutamylation was found exclusively on the E(445) residue. We here describe the analysis of tubulin-α(1A/1B) glutamylation and detyrosination after 2-DE separation, trypsin and proteinase K in-gel digestion, and nanoUPLC-ESI-QqTOF-MS/MS of mouse brain and bovine microtubules. Tyrosinated, detyrosinated, and Δ2-tubulin-α(1A/1B) CTTs were identified on the basis of a comparison of fragmentation patterns and retention times between endogenous and synthetic peptides. Stringent acceptance criteria were adapted for the identification of novel glutamylation sites. In addition to the previously identified site at E(445), glutamylation on mouse and bovine tubulin-α(1A/1B) CTTs was identified on E(441) and E(443) with MASCOT Expect values below 0.01. O-Methylation of glutamates was also observed.

  17. Scenarios for gluino coannihilation

    SciTech Connect

    Ellis, John; Evans, Jason L.; Luo, Feng; Olive, Keith A.

    2016-02-11

    In this article, we study supersymmetric scenarios in which the gluino is the next-to-lightest supersymmetric particle (NLSP), with a mass sufficiently close to that of the lightest supersymmetric particle (LSP) that gluino coannihilation becomes important. One of these scenarios is the MSSM with soft supersymmetry-breaking squark and slepton masses that are universal at an input GUT renormalization scale, but with non-universal gaugino masses. The other scenario is an extension of the MSSM to include vector-like supermultiplets. In both scenarios, we identify the regions of parameter space where gluino coannihilation is important, and discuss their relations to other regions of parameter space where other mechanisms bring the dark matter density into the range allowed by cosmology. In the case of the non-universal MSSM scenario, we find that the allowed range of parameter space is constrained by the requirement of electroweak symmetry breaking, the avoidance of a charged LSP and the measured mass of the Higgs boson, in particular, as well as the appearance of other dark matter (co)annihilation processes. Nevertheless, LSP masses mX ≲ 8TeV with the correct dark matter density are quite possible. In the case of pure gravity mediation with additional vector-like supermultiplets, changes to the anomaly-mediated gluino mass and the threshold effects associated with these states can make the gluino almost degenerate with the LSP, and we find a similar upper bound.

  18. Scenarios for gluino coannihilation

    DOE PAGES

    Ellis, John; Evans, Jason L.; Luo, Feng; ...

    2016-02-11

    In this article, we study supersymmetric scenarios in which the gluino is the next-to-lightest supersymmetric particle (NLSP), with a mass sufficiently close to that of the lightest supersymmetric particle (LSP) that gluino coannihilation becomes important. One of these scenarios is the MSSM with soft supersymmetry-breaking squark and slepton masses that are universal at an input GUT renormalization scale, but with non-universal gaugino masses. The other scenario is an extension of the MSSM to include vector-like supermultiplets. In both scenarios, we identify the regions of parameter space where gluino coannihilation is important, and discuss their relations to other regions of parametermore » space where other mechanisms bring the dark matter density into the range allowed by cosmology. In the case of the non-universal MSSM scenario, we find that the allowed range of parameter space is constrained by the requirement of electroweak symmetry breaking, the avoidance of a charged LSP and the measured mass of the Higgs boson, in particular, as well as the appearance of other dark matter (co)annihilation processes. Nevertheless, LSP masses mX ≲ 8TeV with the correct dark matter density are quite possible. In the case of pure gravity mediation with additional vector-like supermultiplets, changes to the anomaly-mediated gluino mass and the threshold effects associated with these states can make the gluino almost degenerate with the LSP, and we find a similar upper bound.« less

  19. Establishing the common patterns of future tropospheric ozone under diverse climate change scenarios

    NASA Astrophysics Data System (ADS)

    Jimenez-Guerrero, Pedro; Gómez-Navarro, Juan J.; Jerez, Sonia; Lorente-Plazas, Raquel; Baro, Rocio; Montávez, Juan P.

    2013-04-01

    The impacts of climate change on air quality may affect long-term air quality planning. However, the policies aimed at improving air quality in the EU directives have not accounted for the variations in the climate. Climate change alone influences future air quality through modifications of gas-phase chemistry, transport, removal, and natural emissions. As such, the aim of this work is to check whether the projected changes in gas-phase air pollution over Europe depends on the scenario driving the regional simulation. For this purpose, two full-transient regional climate change-air quality projections for the first half of the XXI century (1991-2050) have been carried out with MM5+CHIMERE system, including A2 and B2 SRES scenarios. Experiments span the periods 1971-2000, as a reference, and 2071-2100, as future enhanced greenhouse gas and aerosol scenarios (SRES A2 and B2). The atmospheric simulations have a horizontal resolution of 25 km and 23 vertical layers up to 100 mb, and were driven by ECHO-G global climate model outputs. The analysis focuses on the connection between meteorological and air quality variables. Our simulations suggest that the modes of variability for tropospheric ozone and their main precursors hardly change under different SRES scenarios. The effect of changing scenarios has to be sought in the intensity of the changing signal, rather than in the spatial structure of the variation patterns, since the correlation between the spatial patterns of variability in A2 and B2 simulation is r > 0.75 for all gas-phase pollutants included in this study. In both cases, full-transient simulations indicate an enhanced enhanced chemical activity under future scenarios. The causes for tropospheric ozone variations have to be sought in a multiplicity of climate factors, such as increased temperature, different distribution of precipitation patterns across Europe, increased photolysis of primary and secondary pollutants due to lower cloudiness, etc

  20. Emissions from international shipping: 2. Impact of future technologies on scenarios until 2050

    NASA Astrophysics Data System (ADS)

    Eyring, V.; KöHler, H. W.; Lauer, A.; Lemper, B.

    2005-09-01

    In this study the today's fleet-average emission factors of the most important ship exhausts are used to calculate emission scenarios for the future. To develop plausible future technology scenarios, first upcoming regulations and compliance with future regulations through technological improvements are discussed. We present geographically resolved emission inventory scenarios until 2050, based on a mid-term prognosis for 2020 and a long-term prognosis for 2050. The scenarios are based on some very strict assumptions on future ship traffic demands and technological improvements. The four future ship traffic demand scenarios are mainly determined by the economic growth, which follows the IPCC SRES storylines. The resulting fuel consumption is projected through extrapolations of historical trends in economic growth, total seaborne trade and number of ships, as well as the average installed power per ship. For the future technology scenarios we assume a diesel-only fleet in 2020 resulting in fuel consumption between 382 and 409 million metric tons (Mt). For 2050 one technology scenario assumes that 25% of the fuel consumed by a diesel-only fleet can be saved by applying future alternative propulsion plants, resulting in a fuel consumption that varies between 402 and 543 Mt. The other scenario is a business-as-usual scenario for a diesel-only fleet even in 2050 and gives an estimate between 536 and 725 Mt. Dependent on how rapid technology improvements for diesel engines are introduced, possible technology reduction factors are applied to the today's fleet-average emission factors of all important species to estimate future ship emissions. Combining the four traffic demand scenarios with the four technology scenarios, our results suggest emissions between 8.8 and 25.0 Tg (NO2) in 2020, and between 3.1 to 38.8 Tg (NO2) in 2050. The development of forecast scenarios for CO2, NOx, SOx, CO, hydrocarbons, and particulate matter is driven by the requirements for global model

  1. Attractive scenario writing.

    PubMed

    Takahashi, Yuzo; Oku, Sachiko Alexandra

    2009-05-01

    This article describes the key steps of scenario writing to facilitate problem-based learning discussion to aid student learning of basic medical science in combination with clinical medicine. The scenario has to amplify and deepen the students' thinking so that they can correlate findings from the case and knowledge from textbooks. This can be achieved in three ways: (1) a comparison of cases; (2) demonstrating a scientific link between symptoms and basic medicine; and (3) introducing a personal and emotional aspect to the scenario. A comparison of two cases enables us to shed light on the pathological differences and think about the underlying biological mechanisms. These include: (a) a comparison of two cases with similar symptoms, but different diseases; (b) a comparison of two cases with different symptoms, but the same cause; and (c) a comparison of two cases, with an easy case, followed by a complicated case. The scenarios may be disclosed in a sequence to show a scientific link between symptoms of the patient and basic medicine, which may help to cultivate a physician with a scientific mind. Examples are given by the relationship between: (a) symptoms, pathology and morphology; and (b) symptoms, pathology and physiology. When the scenario is written in such a way that students are personally and/or emotionally involved in the case, they will be more motivated in learning as if involved in the case themselves. To facilitate this, the scenario can be written in the first-person perspective. Examples include "I had a very bad headache, and vomited several times...", and "I noticed that my father was screaming at night...". The description of the events may be in chronological order with actual time, which makes students feel as if they are really the primary responding person.

  2. Characterization of drCol 15a1b: a novel component of the stem cell niche in the zebrafish retina.

    PubMed

    Gonzalez-Nunez, Veronica; Nocco, Valentina; Budd, Aidan

    2010-08-01

    There is a clear need to develop novel tools to help improve our understanding of stem cell biology, and potentially also the utility of stem cells in regenerative medicine. We report the cloning, functional, and bioinformatic characterization of a novel stem cell marker in the zebrafish retina, drCol 15a1b. The expression pattern of drCol 15a1b is restricted to stem cell niches located in the central nervous system, whereas other collagen XVs are associated with muscle and endothelial tissues. Knocking down drCol 15a1b expression causes smaller eyes, ear defects, and brain edema. Microscopic analysis reveals enhanced proliferation in the morphant eye, with many mitotic nuclei located in the central retina, together with a delayed differentiation of the mature retinal cell types. Besides, several markers known to be expressed in the ciliary marginal zone display broader expression areas in morpholino-injected embryos, suggesting an anomalous diffusion of signaling effectors from the sonic hedgehog and notch pathways. These results indicate that drCol 15a1b is a novel stem cell marker in the central nervous system that has a key role in homing stem cells into specialized niches in the adult organism. Moreover, mutations in the hCol 18a1 gene are responsible for the Knobloch syndrome, which affects brain and retinal structures, suggesting that drCol 15a1b may function similarly to mammalian Col 18a1. Thus, our results shed new light on the signaling pathways that underlie the maintenance of stem cells in the adult organism while helping us to understand the role of extracellular matrix proteins in modulating the signals that determine stem cell differentiation, cell cycle exit and apoptosis.

  3. The SAFRR Tsunami Scenario

    USGS Publications Warehouse

    Porter, K.; Jones, Lucile M.; Ross, Stephanie L.; Borrero, J.; Bwarie, J.; Dykstra, D.; Geist, Eric L.; Johnson, L.; Kirby, Stephen H.; Long, K.; Lynett, P.; Miller, K.; Mortensen, Carl E.; Perry, S.; Plumlee, G.; Real, C.; Ritchie, L.; Scawthorn, C.; Thio, H.K.; Wein, Anne; Whitmore, P.; Wilson, R.; Wood, Nathan J.; Ostbo, Bruce I.; Oates, Don

    2013-01-01

    The U.S. Geological Survey and several partners operate a program called Science Application for Risk Reduction (SAFRR) that produces (among other things) emergency planning scenarios for natural disasters. The scenarios show how science can be used to enhance community resiliency. The SAFRR Tsunami Scenario describes potential impacts of a hypothetical, but realistic, tsunami affecting California (as well as the west coast of the United States, Alaska, and Hawaii) for the purpose of informing planning and mitigation decisions by a variety of stakeholders. The scenario begins with an Mw 9.1 earthquake off the Alaska Peninsula. With Pacific basin-wide modeling, we estimate up to 5m waves and 10 m/sec currents would strike California 5 hours later. In marinas and harbors, 13,000 small boats are damaged or sunk (1 in 3) at a cost of $350 million, causing navigation and environmental problems. Damage in the Ports of Los Angeles and Long Beach amount to $110 million, half of it water damage to vehicles and containerized cargo. Flooding of coastal communities affects 1800 city blocks, resulting in $640 million in damage. The tsunami damages 12 bridge abutments and 16 lane-miles of coastal roadway, costing $85 million to repair. Fire and business interruption losses will substantially add to direct losses. Flooding affects 170,000 residents and workers. A wide range of environmental impacts could occur. An extensive public education and outreach program is underway, as well as an evaluation of the overall effort.

  4. Biomass Scenario Model

    SciTech Connect

    2015-09-01

    The Biomass Scenario Model (BSM) is a unique, carefully validated, state-of-the-art dynamic model of the domestic biofuels supply chain which explicitly focuses on policy issues, their feasibility, and potential side effects. It integrates resource availability, physical/technological/economic constraints, behavior, and policy. The model uses a system dynamics simulation (not optimization) to model dynamic interactions across the supply chain.

  5. Characterization of maritime scenarios

    NASA Astrophysics Data System (ADS)

    Low, Tom B.; Hudak, D. R.

    1992-09-01

    Meteorological modules were developed to describe characteristic maritime scenarios in various oceanic areas for DREV complimentarity studies of shipboard defense. The best means of depicting the maritime atmospheric environment was found to be on the basis of air mass analysis. A methodology was developed whereby, through a mixture of man-machine objective analysis of upper air radiosonde measurements at the 850, 700, and 500 mb levels, typical airmasses could be identified. Characteristic scenarios were then defined based on physical considerations of air mass theory. Utilizing an extensive 10-year set of worldwide radiosonde, ozondesonde, and surface observations collected from a combination of land-based stations, oceanographic buoys, and weather ships, frequency and correlation statistics of various global and derived meteorological and oceanographic parameters were established for the CANLANT, NORLANT, WESTLANT, EASTLANT, IBERLANT, MARPAC regions, the ARCTIC OCEAN to 85 degree(s)N, the BALTIC SEA, MEDITERRANEAN SEA, PERSIAN GULF, RED SEA, GULF OF OMAN, and the INDIAN OCEAN. These descriptions included atmospheric profiles of pressure, temperature, dewpoint and relative humidity, wind speeds and direction, refractivity index, and ozone concentration from the surface to approximately 20 km., as well as associated surface visibility, clouds and weather, sea state, and duct height conditions. Many of the derived parameters were found to be a strong function of the defining airmass scenarios. The spatial distribution of these scenarios was also determined.

  6. Global temperature change from the transport sectors: Historical development and future scenarios

    NASA Astrophysics Data System (ADS)

    Skeie, Ragnhild Bieltvedt; Fuglestvedt, Jan; Berntsen, Terje; Lund, Marianne Tronstad; Myhre, Gunnar; Rypdal, Kristin

    2009-12-01

    Transport affects climate directly and indirectly through mechanisms that operate on very different timescales and cause both warming and cooling. We calculate contributions to the historical development in global mean temperature for the main transport sectors (road transport, aviation, shipping and rail) based on estimates of historical emissions and by applying knowledge about the various forcing mechanisms from detailed studies. We also calculate the development in future global mean temperature for four transport scenarios consistent with the IPCC SRES scenarios, one mitigation scenario and one sensitivity test scenario. There are large differences between the transport sectors in terms of sign and magnitude of temperature effects and with respect to the contributions from the long- and short-lived components. Since pre-industrial times, we calculate that transport in total has contributed 9% of total net man-made warming in the year 2000. The dominating contributor to warming is CO 2, followed by tropospheric O 3. By sector, road transport is the largest contributor; 11% of the warming in 2000 is due to this sector. Likewise, aviation has contributed 4% and rail ˜1%. Shipping, on the other hand, has caused a net cooling up to year 2000, with a contribution of -7%, due to the effects of SO 2 and NO x emissions. The total net contribution from the transport sectors to total man-made warming is ˜15% in 2050, and reaches 20% in 2100 in the A1 and B1 scenarios. For all scenarios and throughout the century, road transport is the dominating contributor to warming. Due to the anticipated reduction in sulphur content of fuels, the net effect of shipping changes from cooling to warming by the end of the century. Significant uncertainties are related to the estimates of historical and future net warming mainly due to cirrus, contrails and aerosol effects, as well as uncertainty in climate sensitivity.

  7. It's the Heat AND the Humidity -- Assessment of Extreme Heat Scenarios to Enable the Assessment of Climate Impacts on Public Health

    NASA Technical Reports Server (NTRS)

    Crosson, William L; Al-Hamdan, Mohammad Z.; Economou, Sigrid, A.; Estes, Maurice G.; Estes, Sue M.; Puckett, Mark; Quattrochi, Dale A

    2013-01-01

    In the United States, extreme heat is the most deadly weather-related hazard. In the face of a warming climate and urbanization, which contributes to local-scale urban heat islands, it is very likely that extreme heat events (EHEs) will become more common and more severe in the U.S. In a NASA-funded project supporting the National Climate Assessment, we are providing historical and future measures of extreme heat to enable assessments of the impacts of heat on public health over the coterminous U.S. We use atmospheric temperature and humidity information from meteorological reanalysis and from Global Climate Models (GCMs) to provide data on past and future heat events. The project s emphasis is on providing assessments of the magnitude, frequency and geographic distribution of extreme heat in the U.S. to facilitate public health studies. In our approach, long-term climate change is captured with GCM output, and the temporal and spatial characteristics of short-term extremes are represented by the reanalysis data. Two future time horizons, 2040 and 2090, are the focus of future assessments; these are compared to the recent past period of 1981-2000. We are characterizing regional-scale temperature and humidity conditions using GCM output for two climate change scenarios (A2 and A1B) defined in the Special Report on Emissions Scenarios (SRES). For each future period, 20 years of multi-model GCM output have been analyzed to develop a heat stress climatology based on statistics of extreme heat indicators. Differences between the two future and past periods have been used to define temperature and humidity changes on a monthly time scale and regional spatial scale. These changes, combined with hourly historical meteorological data at a spatial scale (12 km) much finer than that of GCMs, enable us to create future climate realizations, from which we compute the daily heat stress measures and related spatially-specific climatological fields. These include the mean annual

  8. Physiological Properties of hERG 1a/1b Heteromeric Currents and a hERG 1b-specific Mutation Associated with Long QT Syndrome

    PubMed Central

    Sale, Harinath; Wang, Jinling; O'Hara, Thomas J.; Tester, David J.; Phartiyal, Pallavi; He, Jia-Qiang; Rudy, Yoram; Ackerman, Michael J.; Robertson, Gail A.

    2009-01-01

    Cardiac IKr is a critical repolarizing current in the heart and a target for inherited and acquired long QT syndrome (LQTS). Biochemical and functional studies have demonstrated that IKr channels are heteromers composed of both hERG 1a and 1b subunits, yet our current understanding of IKr functional properties derives primarily from studies of homo-oligomers of the original hERG 1a isolate. Here we examine currents produced by hERG 1a and 1a/1b channels expressed in HEK-293 cells at near-physiological temperatures. We find that heteromeric hERG 1a/1b currents are much larger than hERG 1a currents and conduct 80% more charge during an action potential. This surprising difference corresponds to a two-fold increase in the apparent rates of activation and recovery from inactivation, thus reducing rectification and facilitating current rebound during repolarization. Kinetic modeling shows these gating differences account quantitatively for the differences in current amplitude between the two channel types. Drug sensitivity was also different. Compared to homomeric 1a channels, heteromeric 1a/1b channels were inhibited by E-4031 with a slower time course and a corresponding four-fold shift in the IC50. The importance of hERG 1b in vivo is supported by the identification of a 1b-specific A8V missense mutation in 1/269 unrelated genotype-negative LQTS patients and absent in 400 control alleles. Mutant 1bA8V expressed alone or with hERG 1a in HEK-293 cells dramatically reduced 1b protein levels. Thus, mutations specifically disrupting hERG 1b function are expected to reduce cardiac IKr and enhance drug sensitivity, and represent a potential mechanism underlying inherited or acquired LQTS. PMID:18776039

  9. Loss of Slc4a1b Chloride/Bicarbonate Exchanger Function Protects Mechanosensory Hair Cells from Aminoglycoside Damage in the Zebrafish Mutant persephone

    PubMed Central

    Hailey, Dale W.; Roberts, Brock; Owens, Kelly N.; Stewart, Andrew K.; Linbo, Tor; Pujol, Remy; Alper, Seth L.; Rubel, Edwin W.; Raible, David W.

    2012-01-01

    Mechanosensory hair cell death is a leading cause of hearing and balance disorders in the human population. Hair cells are remarkably sensitive to environmental insults such as excessive noise and exposure to some otherwise therapeutic drugs. However, individual responses to damaging agents can vary, in part due to genetic differences. We previously carried out a forward genetic screen using the zebrafish lateral line system to identify mutations that alter the response of larval hair cells to the antibiotic neomycin, one of a class of aminoglycoside compounds that cause hair cell death in humans. The persephone mutation confers resistance to aminoglycosides. 5 dpf homozygous persephone mutants are indistinguishable from wild-type siblings, but differ in their retention of lateral line hair cells upon exposure to neomycin. The mutation in persephone maps to the chloride/bicarbonate exchanger slc4a1b and introduces a single Ser-to-Phe substitution in zSlc4a1b. This mutation prevents delivery of the exchanger to the cell surface and abolishes the ability of the protein to import chloride across the plasma membrane. Loss of function of zSlc4a1b reduces hair cell death caused by exposure to the aminoglycosides neomycin, kanamycin, and gentamicin, and the chemotherapeutic drug cisplatin. Pharmacological block of anion transport with the disulfonic stilbene derivatives DIDS and SITS, or exposure to exogenous bicarbonate, also protects hair cells against damage. Both persephone mutant and DIDS-treated wild-type larvae show reduced uptake of labeled aminoglycosides. persephone mutants also show reduced FM1-43 uptake, indicating a potential impact on mechanotransduction-coupled activity in the mutant. We propose that tight regulation of the ionic environment of sensory hair cells, mediated by zSlc4a1b activity, is critical for their sensitivity to aminoglcyoside antibiotics. PMID:23071446

  10. Additive effects of levonorgestrel and ethinylestradiol on brain aromatase (cyp19a1b) in zebrafish specific in vitro and in vivo bioassays.

    PubMed

    Hinfray, N; Tebby, C; Garoche, C; Piccini, B; Bourgine, G; Aït-Aïssa, S; Kah, O; Pakdel, F; Brion, F

    2016-09-15

    Estrogens and progestins are widely used in combination in human medicine and both are present in aquatic environment. Despite the joint exposure of aquatic wildlife to estrogens and progestins, very little information is available on their combined effects. In the present study we investigated the effect of ethinylestradiol (EE2) and Levonorgestrel (LNG), alone and in mixtures, on the expression of the brain specific ER-regulated cyp19a1b gene. For that purpose, recently established zebrafish-derived tools were used: (i) an in vitro transient reporter gene assay in a human glial cell line (U251-MG) co-transfected with zebrafish estrogen receptors (zfERs) and the luciferase gene under the control of the zebrafish cyp19a1b gene promoter and (ii) an in vivo bioassay using a transgenic zebrafish expressing GFP under the control of the zebrafish cyp19a1b gene promoter (cyp19a1b-GFP). Concentration-response relationships for single chemicals were modeled and used to design the mixture experiments following a ray design. The results from mixture experiments were analyzed to predict joint effects according to concentration addition and statistical approaches were used to characterize the potential interactions between the components of the mixtures (synergism/antagonism). We confirmed that some progestins could elicit estrogenic effects in fish brain. In mixtures, EE2 and LNG exerted additive estrogenic effects both in vitro and in vivo, suggesting that some environmental progestin could exert effects that will add to those of environmental (xeno-)estrogens. Moreover, our zebrafish specific assays are valuable tools that could be used in risk assessment for both single chemicals and their mixtures.

  11. 5-HT1A/1B Receptors as Targets for Optimizing Pigmentary Responses in C57BL/6 Mouse Skin to Stress

    PubMed Central

    Wu, Hua-Li; Pang, Si-Lin; Liu, Qiong-Zhen; Wang, Qian; Cai, Min-Xuan; Shang, Jing

    2014-01-01

    Stress has been reported to induce alterations of skin pigmentary response. Acute stress is associated with increased turnover of serotonin (5-hydroxytryptamine; 5-HT) whereas chronic stress causes a decrease. 5-HT receptors have been detected in pigment cells, indicating their role in skin pigmentation. To ascertain the precise role of 5-HT in stress-induced pigmentary responses, C57BL/6 mice were subjected to chronic restraint stress and chronic unpredictable mild stress (CRS and CUMS, two models of chronic stress) for 21 days, finally resulting in abnormal pigmentary responses. Subsequently, stressed mice were characterized by the absence of a black pigment in dorsal coat. The down-regulation of tyrosinase (TYR) and tyrosinase-related proteins (TRP1 and TRP2) expression in stressed skin was accompanied by reduced levels of 5-HT and decreased expression of 5-HT receptor (5-HTR) system. In both murine B16F10 melanoma cells and normal human melanocytes (NHMCs), 5-HT had a stimulatory effect on melanin production, dendricity and migration. When treated with 5-HT in cultured hair follicles (HFs), the increased expression of melanogenesis-related genes and the activation of 5-HT1A, 1B and 7 receptors also occurred. The serum obtained from stressed mice showed significantly decreased tyrosinase activity in NHMCs compared to that from nonstressed mice. The decrease in tyrosinase activity was further augmented in the presence of 5-HTR1A, 1B and 7 antagonists, WAY100635, SB216641 and SB269970. In vivo, stressed mice received 5-HT precursor 5-hydroxy-l-tryptophan (5-HTP), a member of the class of selective serotonin reuptake inhibitors (fluoxetine; FX) and 5-HTR1A/1B agonists (8-OH-DPAT/CP94253), finally contributing to the normalization of pigmentary responses. Taken together, these data strongly suggest that the serotoninergic system plays an important role in the regulation of stress-induced depigmentation, which can be mediated by 5-HT1A/1B receptors. 5-HT and 5-HTR1A

  12. Assessment of land degradation susceptibility by scenario analysis. A case study in Southern Tuscany, Italy

    NASA Astrophysics Data System (ADS)

    Maerker, Michael; Angeli, Luca; Bottai, Lorenzo; Innocenti, Lucia; Sicilliano, Giuseppina

    2010-05-01

    In the Mediterranean area land degradation phenomena are becoming more and more important due to future climate change and increasing climate variability as highlighted in recent global assessment projects such as the "Millennium Ecosystem Assessment" or "The Dialogue on water and Climate". Thus, there are consistent evidences that extreme events such as droughts and floods are more frequent than before. On the other hand the Mediterranean area is strongly influenced by human activities such as cultivations over hundreds of years. However, in the last decades the cultivation methods and techniques are subject to profound changes such as mechanization, use of fertilizer and pesticides, remodellation of entire hillslopes etc.. This particular situation leads to, and aggravates the existing stress on land resources. As a result, land degradation and soil erosion phenomena are leading to decreasing soil productivity or the loss of fertile top soil and related water quality and quantity issues. The aim of this paper is to assess land degradation sensitivity by scenario analysis. As a proxi for land degradation surface wash erosion processes such as rill-interill erosion processes are chosen. This present day processes are identified by aerial photo interpretation and subsequently modelled with a simple RUSLE approach on a monthly basis. In this study boundary conditions such as future precipitation were taken form the A2 future climate scenario published by the International Panel on Climate Change (IPCC) - Special Report on Emission Scenarios (SRES). Moreover, current landuse was identified from aerial photographs and future land use scenarios were developed considering ecological and socio-economical issues for present day conditions of the test area. Subsequently, the different climate and landuse scenarios were analysed to study soil erosion susceptibility on the landscape scale. The study shows that even with a decline in precipitation volume till 2070, in some

  13. Evolving practices in environmental scenarios: a new scenario typology

    NASA Astrophysics Data System (ADS)

    Wilkinson, Angela; Eidinow, Esther

    2008-10-01

    A new approach to scenarios focused on environmental concerns, changes and challenges, i.e. so-called 'environmental scenarios', is necessary if global environmental changes are to be more effectively appreciated and addressed through sustained and collaborative action. On the basis of a comparison of previous approaches to global environmental scenarios and a review of existing scenario typologies, we propose a new scenario typology to help guide scenario-based interventions. This typology makes explicit the types of and/or the approaches to knowledge ('the epistemologies') which underpin a scenario approach. Drawing on previous environmental scenario projects, we distinguish and describe two main types in this new typology: 'problem-focused' and 'actor-centric'. This leads in turn to our suggestion for a third type, which we call 'RIMA'—'reflexive interventionist or multi-agent based'. This approach to scenarios emphasizes the importance of the involvement of different epistemologies in a scenario-based process of action learning in the public interest. We suggest that, by combining the epistemologies apparent in the previous two types, this approach can create a more effective bridge between longer-term thinking and more immediate actions. Our description is aimed at scenario practitioners in general, as well as those who work with (environmental) scenarios that address global challenges.

  14. [Variation trends of natural vegetation net primary productivity in China under climate change scenario].

    PubMed

    Zhao, Dong-sheng; Wu, Shao-hong; Yin, Yun-he

    2011-04-01

    Based on the widely used Lund-Potsdam-Jena Dynamic Global Vegetation Model (LPJ) for climate change study, and according to the features of natural environment in China, the operation mechanism of the model was adjusted, and the parameters were modified. With the modified LPJ model and taking 1961-1990 as baseline period, the responses of natural vegetation net primary productivity (NPP) in China to climate change in 1991-2080 were simulated under the Special Report on Emissions Scenarios (SRES) B2 scenario. In 1961-1990, the total NPP of natural vegetation in China was about 3.06 Pg C a(-1); in 1961-2080, the total NPP showed a fluctuant decreasing trend, with an accelerated decreasing rate. Under the condition of slight precipitation change, the increase of mean air temperature would have definite adverse impact on the NPP. Spatially, the NPP decreased from southeast coast to northwest inland, and this pattern would have less variation under climate change. In eastern China with higher NPP, especially in Northeast China, east of North China, and Loess Plateau, the NPP would mainly have a decreasing trend; while in western China with lower NPP, especially in the Tibetan Plateau and Tarim Basin, the NPP would be increased. With the intensive climate change, such a variation trend of NPP would be more obvious.

  15. Scenario Planning in Higher Education.

    ERIC Educational Resources Information Center

    Rieley, James B.

    1997-01-01

    Proposes scenario planning in preparing for the future of higher education. Delineates a methodology for effective scenario planning: identifying potential future scenarios; examining social, economic, political, environmental, and technological influences; exploring mental models while looking through systems maps, and developing potential…

  16. Biomass Scenario Model Scenario Library: Definitions, Construction, and Description

    SciTech Connect

    Inman, D.; Vimmerstedt, L.; Bush, B.; Peterson, S.

    2014-04-01

    Understanding the development of the biofuels industry in the United States is important to policymakers and industry. The Biomass Scenario Model (BSM) is a system dynamics model of the biomass-to-biofuels system that can be used to explore policy effects on biofuels development. Because of the complexity of the model, as well as the wide range of possible future conditions that affect biofuels industry development, we have not developed a single reference case but instead developed a set of specific scenarios that provide various contexts for our analyses. The purpose of this report is to describe the scenarios that comprise the BSM scenario library. At present, we have the following policy-focused scenarios in our library: minimal policies, ethanol-focused policies, equal access to policies, output-focused policies, technological diversity focused, and the point-of-production- focused. This report describes each scenario, its policy settings, and general insights gained through use of the scenarios in analytic studies.

  17. Repository preclosure accident scenarios

    SciTech Connect

    Yook, H.R.; Arbital, J.G.; Keeton, J.M.; Mosier, J.E.; Weaver, B.S.

    1984-09-01

    Waste-handling operations at a spent-fuel repository were investigated to identify operational accidents that could occur. The facility was subdivided, through systems engineering procedures, into individual operations that involve the waste and one specific component of the waste package, in one specific area of the handling facility. From this subdivision approximately 600 potential accidents involving waste package components were identified and then discussed. Supporting descriptive data included for each accident scenario are distance of drop, speed of collision, weight of package component, and weight of equipment involved. The energy of impact associated with each potential accident is calculated to provide a basis for comparison of the relative severities of all the accidents. The results and conclusions suggest approaches to accident consequence mitigation through waste package and facility design. 35 figures, 9 tables.

  18. Isolation and purification of enniatins A, A(1), B, B(1), produced by Fusarium tricinctum in solid culture, and cytotoxicity effects on Caco-2 cells.

    PubMed

    Meca, G; Ruiz, M J; Soriano, J M; Ritieni, A; Moretti, A; Font, G; Mañes, J

    2010-09-01

    Enniatins (ENs) are antibiotic compounds of hexadepsipeptidic structure produced by several strains of Fusarium spp. The ENs A, A(1), B, B(1) were purified from extracts of Fusarium tricinctum grown on a solid medium of corn, by a low pressure liquid chromatography (LPLC) on reverse phase of Amberlite XAD-7 followed by semipreparative LC. The purity and the structure of the isolated compounds were confirmed by LC-MS/MS. The technique of the purification of the fungal extract enabled complete separation of the ENs A, A(1), B, B(1) with a mean purity of 97% for all the compounds. The cytoxicity of the ENs was tested in the cell lines of human origin (epithelial colorectal adenocarcinoma cells, Caco-2) by MTT assays. Only EN A(1) and B(1) evoked toxicity at the tested concentrations. The inhibitory concentration (IC(50)) for EN A(1) on Caco-2 cells was 12.3 microM, whereas the IC(50) produced by the EN B(1) was 19.5 microM. This study indicates that ENs, fungal metabolites that are commonly found in corn and in general in product composed by corn, may have a toxic potential for human health. Copyright 2010 Elsevier Ltd. All rights reserved.

  19. Mission Scenario Development Workbench

    NASA Technical Reports Server (NTRS)

    Kordon, Mark; Baker, John; Gilbert, John; Hanks, David; Mandutianu, Dan; Hooper, David

    2006-01-01

    The Mission Scenario Development Workbench (MSDW) is a multidisciplinary performance analysis software tool for planning and optimizing space missions. It provides a number of new capabilities that are particularly useful for planning the surface activities on other planets. MSDW enables rapid planning of a space mission and supports flight system and scientific-instrumentation trades. It also provides an estimate of the ability of flight, ground, and science systems to meet high-level mission goals and provides means of evaluating expected mission performance at an early stage of planning in the project life cycle. In MSDW, activity plans and equipment-list spreadsheets are integrated with validated parameterized simulation models of spacecraft systems. In contrast to traditional approaches involving worst-case estimates with large margins, the approach embodied in MSDW affords more flexibility and more credible results early in the lifecycle through the use of validated, variable- fidelity models of spacecraft systems. MSDW is expected to help maximize the scientific return on investment for space missions by understanding early the performance required to have a successful mission while reducing the risk of costly design changes made at late stages in the project life cycle.

  20. Prediction of the potential geographic distribution of the ectomycorrhizal mushroom Tricholoma matsutake under multiple climate change scenarios.

    PubMed

    Guo, Yanlong; Li, Xin; Zhao, Zefang; Wei, Haiyan; Gao, Bei; Gu, Wei

    2017-04-10

    Effective conservation and utilization strategies for natural biological resources require a clear understanding of the geographic distribution of the target species. Tricholoma matsutake is an ectomycorrhizal (ECM) mushroom with high ecological and economic value. In this study, the potential geographic distribution of T. matsutake under current conditions in China was simulated using MaxEnt software based on species presence data and 24 environmental variables. The future distributions of T. matsutake in the 2050s and 2070s were also projected under the RCP 8.5, RCP 6, RCP 4.5 and RCP 2.6 climate change emission scenarios described in the Special Report on Emissions Scenarios (SRES) by the Intergovernmental Panel on Climate Change (IPCC). The areas of marginally suitable, suitable and highly suitable habitats for T. matsutake in China were approximately 0.22 × 10(6) km(2), 0.14 × 10(6) km(2), and 0.11 × 10(6) km(2), respectively. The model simulations indicated that the area of marginally suitable habitats would undergo a relatively small change under all four climate change scenarios; however, suitable habitats would significantly decrease, and highly suitable habitat would nearly disappear. Our results will be influential in the future ecological conservation and management of T. matsutake and can be used as a reference for studies on other ectomycorrhizal mushroom species.

  1. Prediction of the potential geographic distribution of the ectomycorrhizal mushroom Tricholoma matsutake under multiple climate change scenarios

    PubMed Central

    Guo, Yanlong; Li, Xin; Zhao, Zefang; Wei, Haiyan; Gao, Bei; Gu, Wei

    2017-01-01

    Effective conservation and utilization strategies for natural biological resources require a clear understanding of the geographic distribution of the target species. Tricholoma matsutake is an ectomycorrhizal (ECM) mushroom with high ecological and economic value. In this study, the potential geographic distribution of T. matsutake under current conditions in China was simulated using MaxEnt software based on species presence data and 24 environmental variables. The future distributions of T. matsutake in the 2050s and 2070s were also projected under the RCP 8.5, RCP 6, RCP 4.5 and RCP 2.6 climate change emission scenarios described in the Special Report on Emissions Scenarios (SRES) by the Intergovernmental Panel on Climate Change (IPCC). The areas of marginally suitable, suitable and highly suitable habitats for T. matsutake in China were approximately 0.22 × 106 km2, 0.14 × 106 km2, and 0.11 × 106 km2, respectively. The model simulations indicated that the area of marginally suitable habitats would undergo a relatively small change under all four climate change scenarios; however, suitable habitats would significantly decrease, and highly suitable habitat would nearly disappear. Our results will be influential in the future ecological conservation and management of T. matsutake and can be used as a reference for studies on other ectomycorrhizal mushroom species. PMID:28393865

  2. Prediction of the potential geographic distribution of the ectomycorrhizal mushroom Tricholoma matsutake under multiple climate change scenarios

    NASA Astrophysics Data System (ADS)

    Guo, Yanlong; Li, Xin; Zhao, Zefang; Wei, Haiyan; Gao, Bei; Gu, Wei

    2017-04-01

    Effective conservation and utilization strategies for natural biological resources require a clear understanding of the geographic distribution of the target species. Tricholoma matsutake is an ectomycorrhizal (ECM) mushroom with high ecological and economic value. In this study, the potential geographic distribution of T. matsutake under current conditions in China was simulated using MaxEnt software based on species presence data and 24 environmental variables. The future distributions of T. matsutake in the 2050s and 2070s were also projected under the RCP 8.5, RCP 6, RCP 4.5 and RCP 2.6 climate change emission scenarios described in the Special Report on Emissions Scenarios (SRES) by the Intergovernmental Panel on Climate Change (IPCC). The areas of marginally suitable, suitable and highly suitable habitats for T. matsutake in China were approximately 0.22 × 106 km2, 0.14 × 106 km2, and 0.11 × 106 km2, respectively. The model simulations indicated that the area of marginally suitable habitats would undergo a relatively small change under all four climate change scenarios; however, suitable habitats would significantly decrease, and highly suitable habitat would nearly disappear. Our results will be influential in the future ecological conservation and management of T. matsutake and can be used as a reference for studies on other ectomycorrhizal mushroom species.

  3. Learning from global emissions scenarios

    NASA Astrophysics Data System (ADS)

    O'Neill, Brian C.; Nakicenovic, Nebojsa

    2008-10-01

    Scenarios of global greenhouse gas emissions have played a key role in climate change analysis for over twenty years. Currently, several research communities are organizing to undertake a new round of scenario development in the lead-up to the Fifth Assessment Report of the Intergovernmental Panel on Climate Change (IPCC). To help inform this process, we assess a number of past efforts to develop and learn from sets of global greenhouse gas emissions scenarios. We conclude that while emissions scenario exercises have likely had substantial benefits for participating modeling teams and produced insights from individual models, learning from the exercises taken as a whole has been more limited. Model comparison exercises have typically focused on the production of large numbers of scenarios while investing little in assessing the results or the production process, perhaps on the assumption that later assessment efforts could play this role. However, much of this assessment potential remains untapped. Efforts such as scenario-related chapters of IPCC reports have been most informative when they have gone to extra lengths to carry out more specific comparison exercises, but in general these assessments do not have the remit or resources to carry out the kind of detailed analysis of scenario results necessary for drawing the most useful conclusions. We recommend that scenario comparison exercises build-in time and resources for assessing scenario results in more detail at the time when they are produced, that these exercises focus on more specific questions to improve the prospects for learning, and that additional scenario assessments are carried out separately from production exercises. We also discuss the obstacles to better assessment that might exist, and how they might be overcome. Finally, we recommend that future work include much greater emphasis on understanding how scenarios are actually used, as a guide to improving scenario production.

  4. Climate change impacts on water availability: developing regional scenarios for agriculture of the Former Soviet Union countries of Central Asia

    NASA Astrophysics Data System (ADS)

    Kirilenko, A.; Dronin, N.

    2010-12-01

    Water is the major factor, limiting agriculture of the five Former Soviet Union (FSU) of Central Asia. Elevated topography prevents moist and warm air from the Atlantic and Indian Oceans from entering the region.With exception of Kazakhstan, agriculture is generally restricted to oases and irrigated lands along the major rivers and canals. Availability of water for irrigation is the major factor constraining agriculture in the region, and conflicts over water are not infrequent. The current water crisis in the region is largely due to human activity; however the region is also strongly impacted by the climate. In multiple locations, planned and autonomous adaptations to climate change have already resulted in changes in agriculture, such as a dramatic increase in irrigation, or shift in crops towards the ones better suited for warmer and dryer climate; however, it is hard to differentiate between the effects of overall management improvement and the avoidance of climate-related losses. Climate change will contribute to water problems, escalating irrigation demand during the drought period, and increasing water loss with evaporation. The future of the countries of the Aral Sea basin then depends on both the regional scenario of water management policy and a global scenario of climate change, and is integrated with global socioeconomic scenarios. We formulate a set of regional policy scenarios (“Business as Usual”, “Falling Behind” and “Closing the Gap”) and demonstrate how each of them corresponds to IPCC SRES scenarios, the latter used as an input to the General Circulation Models (GCMs). Then we discuss the relative effectiveness of the introduced scenarios for mitigating water problems in the region, taking into account the adaptation through changing water demand for agriculture. Finally, we introduce the results of multimodel analysis of GCM climate projections, especially in relation to the change in precipitation and frequency of droughts, and

  5. Excitation of the \\tilde{a}\\,^3B_1 and \\tilde{A}\\,^1B_1 states of H2O by low-energy electron impact

    NASA Astrophysics Data System (ADS)

    Hargreaves, L.; Ralphs, K.; Serna, G.; Khakoo, M. A.; Winstead, C.; McKoy, V.

    2012-10-01

    We report measured and calculated differential cross-sections for inelastic scattering of low-energy electrons by water leading to excitation of the dissociative (1b1 → 4a1) 1, 3B1 states. The measurements were taken using conventional energy-loss spectroscopy at incident energies of 9, 10, 12, 15, and 20 eV for scattering angles from 10° to 130°. The calculations were carried out using the Schwinger multichannel method, with a Born-dipole correction applied in the singlet excitation channel. Integral excitation cross sections for the \\tilde{a}\\,^3B_1 and \\tilde{A}\\,^1B_1 states are also derived from the differential cross section results.

  6. Scenario Planning and Collection Development.

    ERIC Educational Resources Information Center

    Giesecke, Joan

    1999-01-01

    Discussion of the future of library collection development and the need for planning focuses on the technique of scenario planning and discusses the results of scenario planning at the University of NebraskaLincoln that examined collection development and digital information. (LRW)

  7. Scenario Planning in Higher Education.

    ERIC Educational Resources Information Center

    Rieley, James

    Scenario planning can help institutions change the mental models used in planning to achieve a focus on the long-term future, rather than on the immediate future. While institutional survival depends upon the ability to detect and adapt to critical changes in the environment, all institutions face a wide range of potential future scenarios. By…

  8. Student Rights and Responsibilities Scenarios.

    ERIC Educational Resources Information Center

    Peterson, Ludwig A.; And Others

    To stimulate interest in student's rights and responsibilities, this resource contains incomplete scenarios dealing with the consequences of knowing and not knowing the law, as it is applied to modern practical situations. The scenarios can be used in high school courses such as government, social problems, history, psychology, and business law.…

  9. Student Rights and Responsibilities Scenarios.

    ERIC Educational Resources Information Center

    Peterson, Ludwig A.; And Others

    To stimulate interest in student's rights and responsibilities, this resource contains incomplete scenarios dealing with the consequences of knowing and not knowing the law, as it is applied to modern practical situations. The scenarios can be used in high school courses such as government, social problems, history, psychology, and business law.…

  10. Futures Scenario in Science Learning

    ERIC Educational Resources Information Center

    Lloyd, David; Vanderhout, Annastasia; Lloyd, Lisa; Atkins, David

    2010-01-01

    In this article we describe our experiences in developing futures scenarios in two science contexts, space science and atmospheric science/climate change. Futures scenario writing can develop scientific literacy by connecting science learning to students' lifeworlds--past, present and future. They also provide a synthesising mechanism for…

  11. China Land-Use Change Simulation Under Climate Mitigation Scenarios

    NASA Astrophysics Data System (ADS)

    DONG, N.; Lin, H.

    2016-12-01

    Future land-use change responses to human activities and plays a significant role in the whole earth system. Land use data in most climatic models are static which result in a decreased accuracy of evaluation of human activities and also largely lower the efficiency of policy makers. After the RCP scenarios came out, the land use change trends in China for the near future were rarely shown. This paper provides a method to simulate the future land use change in China based on climate mitigation scenarios. The MCD12Q1 product of MODIS and HYDE32 data are combined to make the base land use maps for China of 2005 and 2010. Totally four scenarios are made according to the Chinese national land use overall plan outlines and the statistic data from GCAM. Driving factors from social-economic, ecologic and spatial location aspects are considered including GDP, population density, temperature, precipitation, dominant soil type, elevation, slope, distance to roads, distance to rivers and distance to cities. Simulation is then carried out in 14 agricultural-zones desperately with Dyna-CLUE. Each scenario reflects seperate effects of human activities on land use change. Plan scenario represents the stage of a high speed of urban expansion. Under the condition that urban area would not largely change, the other three GCAM scenarios mainly discuss the situations focused on the change of vegetation cover. We find that: (1)The urban area expands largely in Plan scenario, and G2.6 gets the most forest and crop area which shows environment-friendly human activities to the ecologic balance (Figure 1a,1b). (2) Compare to the 2010 land use map, forest increases mainly happen in the northeast China and central plains region under the G2.6 scenario. However, urban expansion under the Plan scenario occurs not in the Yangtze River Delta or Pearl River Delta economic region but in the second or third developed level cities such as Wuhan, Jinan, and Nanchang (Figure1c,1d). (3)The kappa value

  12. Global source-receptor relationships for mercury under present and year 2050 anthropogenic emissions scenarios

    NASA Astrophysics Data System (ADS)

    Corbitt, E. S.; Holmes, C.; Jacob, D. J.; Streets, D. G.; Selin, N. E.; Sorensen, A.; Sunderland, E. M.

    2009-12-01

    We use the GEOS-Chem global 3-D model for mercury, including dynamic coupling of the atmosphere with ocean and land reservoirs, to quantify continental and regional source-receptor relationships for mercury under present and future (2050) conditions. The model includes several recent developments such as oxidation of Hg(0) by Br atoms and improved representation of land-atmosphere exchange. Different SRES scenarios are considered for 2050 anthropogenic emissions, thus providing a range of future projections. We use a tagged tracer simulation to track atmospheric emissions of mercury from specific source regions including their cycling with the surface ocean and short-lived land reservoirs. We identify net source and receptor regions, distinguishing regions for which domestic emissions reductions would be most effective from others which receive deposition predominantly from the global atmospheric pool of mercury. The projected future increase in the contribution of Hg(II) to global mercury emissions results in a shift toward more regional source-receptor relationships.

  13. Fertilizer Emission Scenario Tool for crop management system scenarios

    EPA Pesticide Factsheets

    The Fertilizer Emission Scenario Tool for CMAQ is a high-end computer interface that simulates daily fertilizer application information for any gridded domain. It integrates the Weather Research and Forecasting model and CMAQ.

  14. Spatio-temporal prediction of leaf area index of rubber plantation using HJ-1A/1B CCD images and recurrent neural network

    NASA Astrophysics Data System (ADS)

    Chen, Bangqian; Wu, Zhixiang; Wang, Jikun; Dong, Jinwei; Guan, Liming; Chen, Junming; Yang, Kai; Xie, Guishui

    2015-04-01

    Rubber (Hevea brasiliensis) plantations are one of the most important economic forest in tropical area. Retrieving leaf area index (LAI) and its dynamics by remote sensing is of great significance in ecological study and production management, such as yield prediction and post-hurricane damage evaluation. Thirteen HJ-1A/1B CCD images, which possess the spatial advantage of Landsat TM/ETM+ and 2-days temporal resolution of MODIS, were introduced to predict the spatial-temporal LAI of rubber plantation on Hainan Island by Nonlinear AutoRegressive networks with eXogenous inputs (NARX) model. Monthly measured LAIs at 30 stands by LAI-2000 between 2012 and 2013 were used to explore the LAI dynamics and their relationship with spectral bands and seven vegetation indices, and to develop and validate model. The NARX model, which was built base on input variables of day of year (DOY), four spectral bands and weight difference vegetation index (WDVI), possessed good accuracies during the model building for the data set of training (N = 202, R2 = 0.98, RMSE = 0.13), validation (N = 43, R2 = 0.93, RMSE = 0.24) and testing (N = 43, R2 = 0.87, RMSE = 0.31), respectively. The model performed well during field validation (N = 24, R2 = 0.88, RMSE = 0.24) and most of its mapping results showed better agreement (R2 = 0.54-0.58, RMSE = 0.47-0.71) with the field data than the results of corresponding stepwise regression models (R2 = 0.43-0.51, RMSE = 0.52-0.82). Besides, the LAI statistical values from the spatio-temporal LAI maps and their dynamics, which increased dramatically from late March (2.36 ± 0.59) to early May (3.22 ± 0.64) and then gradually slow down until reached the maximum value in early October (4.21 ± 0.87), were quite consistent with the statistical results of the field data. The study demonstrates the feasibility and reliability of retrieving spatio-temporal LAI of rubber plantations by an artificial neural network (ANN) approach, and provides some insight on the

  15. Atlantic Hurricanes in Future Scenarios and Associated Insurance Losses

    NASA Astrophysics Data System (ADS)

    Kleppek, S.; Wüest, M.; Raible, C. C.; Kitoh, A.; Murakami, H.; Stocker, T. F.; Muccione, V.; Bresch, D. N.

    2009-04-01

    The hurricane season 2005 in the Atlantic was the most intense season since the first records with 28 tropical storms of which 15 reached hurricane character (Trenberth and Shea, 2006). Although this year is considered to be an outlier, a substantial increase of the activity of tropical cyclones (TCs) in the tropical Atlantic over the last decades is documented (Sriver and Huber, 2006; Hoyos et al., 2006; Webster et al. 2005; Emanuel, 2005). The role of the sea surface temperatures in the tropical Atlantic for the tropical storm activity was discussed already in Emanuel (2005) and Hoyos et al. (2006). Future changes of TC activity is currently under debate (e. g. Bengston et al., 2007). We contribute to this by applying our TC detection and tracking method which was developed for ERA-40 data (Kleppek et al., 2008) to time-slice experiments of two models: The ECHAM5 atmospheric model (MPI, Hamburg, Germany) and the 20 km-mesh, high resolution AGCM (MRI, Tsukuba-city, Japan). From each model two climate simulations are available: For the ECHAM5 a control run for the period 1960-90 and a SRES A2 scenario run for the period 2070-2100 and for the Mesh-AGCM a 20 years run with present day conditions and a 20 years run with end-of-21-century A2 conditions. To estimate losses of the ECHAM5- and Mesh-model hurricanes on the US coast, we have developed probabilistic hurricane event sets which are used as input for catXos, the loss model of the Swiss Reinsurance Company. Preliminary results show higher wind speeds of the ECHAM5 scenario run hurricanes than in the control run, but the numbers of the hurricanes of Saffir-Simpson-scale 2 to 4 show no clear difference between the control and scenario run of ECHAM5. Even though the resolution of the simulation is rather high no hurricanes of Saffir-Simpson-scale 5 are detected. The total number of TCs decreases for the scenario run. This applies as much to the TCs over the Atlantic as over the US-coast. References: Bengston L., K

  16. Climate change and voltinism in Californian insect pest species: sensitivity to location, scenario and climate model choice.

    PubMed

    Ziter, Carly; Robinson, Emily A; Newman, Jonathan A

    2012-09-01

    Experimental studies of the impact of climatic change are hampered by their inability to consider multiple climate change scenarios and indeed often consider no more than simple climate sensitivity such as a uniform increase in temperature. Modelling efforts offer the ability to consider a much wider range of realistic climate projections and are therefore useful, in particular, for estimating the sensitivity of impact predictions to differences in geographical location, and choice of climate change scenario and climate model projections. In this study, we used well-established degree-day models to predict the voltinism of 13 agronomically important pests in California, USA. We ran these models using the projections from three Atmosphere-Ocean Coupled Global Circulation Models (AOCGCMs or GCMs), in conjunction with the SRES scenarios. We ran these for two locations representing northern and southern California. We did this for both the 2050s and 2090s. We used anova to partition the variation in the resulting voltinism among time period, climate change scenario, GCM and geographical location. For these 13 pest species, the choice of climate model explained an average of 42% of the total variation in voltinism, far more than did geographical location (33%), time period (17%) or scenario (1%). The remaining 7% of the variation was explained by various interactions, of which the location by GCM interaction was the strongest (5%). Regardless of these sources of uncertainty, a robust conclusion from our work is that all 13 pest species are likely to experience increases in the number of generations that they complete each year. Such increased voltinism is likely to have significant consequences for crop protection and production.

  17. Assessment of vulnerability to future marine processes of urbanized coastal environments by a GIS-based approach: expected scenario in the metropolitan area of Bari (Italy)

    NASA Astrophysics Data System (ADS)

    Mancini, F.; Ceppi, C.; Christopulos, V.

    2013-12-01

    Literature concerning the risk assessment procedures after extreme meteorological events is generally focused on the establishing of relationship between actual severe weather conditions and impact detected over the involved zones. Such an events are classified on the basis of measurements and observation able to assess the magnitude of phenomena or on the basis of related effects on the affected area, the latter being deeply connected with the overall physical vulnerability. However such assessment almost never do consider scenario about expected extreme event and possible pattern of urbanization at the time of impact and nor the spatial and temporal uncertainty of phenomena are taken into account. The drawn of future scenario about coastal vulnerability to marine processes is therefore difficult. This work focuses the study case of the Metropoli Terra di Bari (metropolitan area of Bari, Apulia, Italy) where a coastal vulnerability analysis due to climate changes expected on the basis of expert opinions coming from the scientific community was carried out. Several possible impacts on the coastal environments were considered, in particular sea level rise inundation, flooding due to storm surge and coastal erosion. For such a purpose the methodology base on SRES (Special Report on Emission Scenario) produced by the IPCC (Intergovernmental Panel on Climate Change) was adopted after a regionalization procedure as carried out by Verburgh and others (2006) at the European scale. The open source software SLEUTH, base on the cellular automate principle, was used and the reliability of obtained scenario verified through the Monte Carlo method. Once these scenario were produced, a GIS-based multicriteria methodology was implemented to evaluate the vulnerability of the urbanized coastal area of interest. Several vulnerability maps related are therefore available for different scenario able to consider the degree of hazards and potential development of the typology and extent

  18. Assessment of land degradation susceptibility by scenario analysis: A case study in Southern Tuscany, Italy

    NASA Astrophysics Data System (ADS)

    Märker, Michael; Angeli, Luca; Bottai, Lorenzo; Costantini, Roberto; Ferrari, Raffaella; Innocenti, Lucia; Siciliano, Giuseppina

    2008-01-01

    In the Mediterranean area land degradation phenomena are becoming more and more important due to future climate change and increasing climate variability, as highlighted in recent global assessment projects such as the "Millennium Ecosystem Assessment" or "The Dialogue on Water and Climate". Thus, there is consistent evidence that extreme events such as droughts and floods are more frequent than before. On the other hand the Mediterranean area is strongly influenced by human activities such as cultivation over hundreds of years. However, in the last decades the cultivation methods and techniques are subject to profound changes such as mechanization, use of fertilizers and pesticides, remodellation of entire hillslopes etc. This particular situation leads to, and aggravates the existing stress on land resources. As a result, land degradation and soil erosion phenomena are leading to decreasing soil productivity or the loss of fertile top soil and related water quality and quantity issues. The Centre for Soil Erosion Studies (CRES) in Grosseto, Tuscany recently started a study to identify and monitor changes of land-use in southern Tuscany, Italy. The aim of this study is to assess land degradation sensitivity by scenario analysis. As a proxi for land degradation surface wash erosion processes such as rill and interill erosion processes are chosen. These present day processes are identified by aerial photo interpretation and subsequently modelled with a simple RUSLE approach on a monthly basis. In this study boundary conditions such as future precipitation were taken from the A2 future climate scenario published by the International Panel on Climate Change (IPCC)-Special Report on Emission Scenarios (SRES). Moreover, current land-use was identified from aerial photographs and future land-use scenarios were developed considering ecological and socio-economical issues for present day conditions of the test area. Subsequently, the different climate and land

  19. Multiple High Resolution Climate Scenarios over North America for Application to Water Resources (Invited)

    NASA Astrophysics Data System (ADS)

    Mearns, L. O.

    2009-12-01

    The North American Regional Climate Change Assessment Program (NARCCAP) is an international program that is serving the climate scenario needs of the United States, Canada, and northern Mexico. We are systematically investigating the uncertainties in regional scale projections of future climate and producing high resolution climate change scenarios using multiple regional climate models(RCMs)and multiple global model responses to a future emission scenario, by nesting the RCMs within atmosphere ocean general circulation models (AOGCMs) forced with the A2 SRES scenario, over a domain covering the conterminous US, northern Mexico, and most of Canada. The project also includes a validation component through nesting the participating RCMs within NCEP reanalyses. The basic spatial resolution of the RCM simulations is 50 km. This program includes RCMs that participated in the European PRUDENCE program (HadRM3 and RegCM), the Canadian regional climate model (CRCM) as well as the NCEP regional spectral model (RSM), the NCAR/PSU MM5, and NCAR WRF. Candidate AOGCMs include the Hadley Centre HadCM3, NCAR CCSM, the Canadian CGCM3 and the GFDL model. The resulting climate model runs form the basis for multiple high resolution climate scenarios that can be used in climate change impacts assessments over North America. High resolution (50 km) global time-slice experiments based on the GFDL atmospheric model and the NCAR atmospheric model (CAM3) have also been produced and will be compared with the simulations of the regional models. There also will be opportunities for double nesting over key regions through which additional modelers in the regional modeling community will be able to participate in NARCCAP. Additional key science issues are being investigated such as the importance of compatible physics in the nested and nesting models. Measures of uncertainty across the multiple runs are being developed by geophysical statisticians. In this overview talk, results from Phase II

  20. Predictions of potential geographical distribution and quality of Schisandra sphenanthera under climate change

    PubMed Central

    Guo, Yanlong; Lu, Chunyan; Gao, Bei

    2016-01-01

    Climate change will significantly affect plant distribution as well as the quality of medicinal plants. Although numerous studies have analyzed the effect of climate change on future habitats of plants through species distribution models (SDMs), few of them have incorporated the change of effective content of medicinal plants. Schisandra sphenanthera Rehd. et Wils. is an endangered traditional Chinese medical plant which is mainly located in the Qinling Mountains. Combining fuzzy theory and a maximum entropy model, we obtained current spatial distribution of quality assessment for S. spenanthera. Moreover, the future quality and distribution of S. spenanthera were also projected for the periods 2020s, 2050s and 2080s under three different climate change scenarios (SRES-A1B, SRES-A2 and SRES-B1 emission scenarios) described in the Special Report on Emissions Scenarios (SRES) of IPCC (Intergovernmental Panel on Climate Change). The results showed that the moderately suitable habitat of S. sphenanthera under all climate change scenarios remained relatively stable in the study area. The highly suitable habitat of S. sphenanthera would gradually decrease in the future and a higher decline rate of the highly suitable habitat area would occur under climate change scenarios SRES-A1B and SRES-A2. The result suggested that in the study area, there would be no more highly suitable habitat areas for S. sphenanthera when the annual mean temperature exceeds 20 °C or its annual precipitation exceeds 1,200 mm. Our results will be influential in the future ecological conservation and management of S. sphenanthera and can be taken as a reference for habitat suitability assessment research for other medicinal plants. PMID:27781160

  1. Predictions of potential geographical distribution and quality of Schisandra sphenanthera under climate change.

    PubMed

    Guo, Yanlong; Wei, Haiyan; Lu, Chunyan; Gao, Bei; Gu, Wei

    2016-01-01

    Climate change will significantly affect plant distribution as well as the quality of medicinal plants. Although numerous studies have analyzed the effect of climate change on future habitats of plants through species distribution models (SDMs), few of them have incorporated the change of effective content of medicinal plants. Schisandra sphenanthera Rehd. et Wils. is an endangered traditional Chinese medical plant which is mainly located in the Qinling Mountains. Combining fuzzy theory and a maximum entropy model, we obtained current spatial distribution of quality assessment for S. spenanthera. Moreover, the future quality and distribution of S. spenanthera were also projected for the periods 2020s, 2050s and 2080s under three different climate change scenarios (SRES-A1B, SRES-A2 and SRES-B1 emission scenarios) described in the Special Report on Emissions Scenarios (SRES) of IPCC (Intergovernmental Panel on Climate Change). The results showed that the moderately suitable habitat of S. sphenanthera under all climate change scenarios remained relatively stable in the study area. The highly suitable habitat of S. sphenanthera would gradually decrease in the future and a higher decline rate of the highly suitable habitat area would occur under climate change scenarios SRES-A1B and SRES-A2. The result suggested that in the study area, there would be no more highly suitable habitat areas for S. sphenanthera when the annual mean temperature exceeds 20 °C or its annual precipitation exceeds 1,200 mm. Our results will be influential in the future ecological conservation and management of S. sphenanthera and can be taken as a reference for habitat suitability assessment research for other medicinal plants.

  2. Franck-Condon factors perturbed by damped harmonic oscillators: Solvent enhanced X 1Ag ↔ A1B1u absorption and fluorescence spectra of perylene

    NASA Astrophysics Data System (ADS)

    Wang, Chen-Wen; Yang, Ling; Zhu, Chaoyuan; Yu, Jian-Guo; Lin, Sheng-Hsien

    2014-08-01

    Damped harmonic oscillators are utilized to calculate Franck-Condon factors within displaced harmonic oscillator approximation. This is practically done by scaling unperturbed Hessian matrix that represents local modes of force constants for molecule in gaseous phase, and then by diagonalizing perturbed Hessian matrix it results in direct modification of Huang-Rhys factors which represent normal modes of solute molecule perturbed by solvent environment. Scaling parameters are empirically introduced for simulating absorption and fluorescence spectra of an isolated solute molecule in solution. The present method is especially useful for simulating vibronic spectra of polycyclic aromatic hydrocarbon molecules in which hydrogen atom vibrations in solution can be scaled equally, namely the same scaling factor being applied to all hydrogen atoms in polycyclic aromatic hydrocarbons. The present method is demonstrated in simulating solvent enhanced X 1Ag ↔ A1B1u absorption and fluorescence spectra of perylene (medium-sized polycyclic aromatic hydrocarbon) in benzene solution. It is found that one of six active normal modes v10 is actually responsible to the solvent enhancement of spectra observed in experiment. Simulations from all functionals (TD) B3LYP, (TD) B3LYP35, (TD) B3LYP50, and (TD) B3LYP100 draw the same conclusion. Hence, the present method is able to adequately reproduce experimental absorption and fluorescence spectra in both gas and solution phases.

  3. Comparison of HCV NS3 protease and NS5B polymerase inhibitor activity in 1a, 1b and 2a replicons and 2a infectious virus.

    PubMed

    Paulson, Matthew S; Yang, Huiling; Shih, I-hung; Feng, Joy Y; Mabery, Eric M; Robinson, Margaret F; Zhong, Weidong; Delaney, William E

    2009-08-01

    The hepatitis C virus infection system represents an important new tool for drug discovery. In this study, we compared the in vitro antiviral efficacy of several NS3 and NS5B inhibitors in genotype 1a, 1b, and 2a replicons and in the 2a infectious virus system. The nucleoside inhibitor 2'-C-methyl adenosine showed similar efficacy in each system tested. Three non-nucleoside inhibitors had small differences in potency between genotype 1a and 1b. In contrast, there was a dramatic loss of potency for these non-nucleoside inhibitors in the genotype 2a replicon, 2a infectious virus, and 2a NS5B biochemical assays. The protease inhibitor BILN-2061 had similar efficacy against 1a and 1b replicons but was 61-109-fold less potent against the 2a replicon and virus, respectively. VX-950, a covalent protease inhibitor, had similar efficacy (<3-fold changes in EC(50)) regardless of genotype or subtype. Importantly, we observed a significant correlation (p<0.0001) in antiviral potency between the 2a replicon and 2a infectious virus for all classes of compounds tested.

  4. On the process of cellular division in Escherichia coli: isolation and characterization of penicillin-binding proteins 1a, 1b, and 3.

    PubMed Central

    Tamura, T; Suzuki, H; Nishimura, Y; Mizoguchi, J; Hirota, Y

    1980-01-01

    Multiple mutants of Escherichia coli defective in penicillin-binding proteins (PBPs) were constructed, and into these strains Co1E1 plasmids carrying the genes for PBP-1a, -1b, or -3 were introduced. From these plasmid-carrying strains, PBP-1a and -1b were purified by ampicillin-Sepharose affinity chromatography and PBP-3 by cephalexin-Sepharose affinity chromatography. Improved purification was achieved by differential elution with NH2OH. Purified PBP-1b synthesized murein when added to the membrane fraction of a PBP-1b-defective mutant, which by itself failed to support murein synthesis in vitro. The PBP-1b preparation was able to synthesize murein from the lipid intermediate extracted with chloroform/methanol but was unable to utilize UDP-linked precursors for murein synthesis. Murein synthesis was inhibited by vancomysin, ristocetin, moenomycin, and enduracidin, but not by beta-lactam antibiotics. The synthesized murein was shown to contain crosslinked muropeptides. Their crosslinking was abolished by action of beta-lactam antibiotics. The PBP-1a and -3 preparations showed substantially no activity for murein synthesis in the same reaction system. None of the three PBPs showed D-alanine carboxypeptidase activity with UDP-N-acetylmuramoyl-pentapeptide as substrate or endopeptidase activity with bis(disaccharide-peptide) as substrate. Images PMID:7001458

  5. "Extended" A1, B8, DR3 haplotype shows remarkable linkage disequilibrium but is similar to nonextended haplotypes in terms of diabetes risk.

    PubMed

    Ide, Akane; Babu, Sunanda R; Robles, David T; Wang, Tianbao; Erlich, Henry A; Bugawan, Teodorica L; Rewers, Marian; Fain, Pamela R; Eisenbarth, George S

    2005-06-01

    To evaluate potential differential diabetes risk of DR3 haplotypes we have evaluated class I alleles as well as two microsatellites previously associated with differential risk associated with DR3 haplotypes. We found that over one-third of patient DR3 chromosomes consisted of an extended DR3 haplotype, from DQ2 to D6S2223 (DQ2, DR3, D6S273-143, MIC-A5.1, HLA-B8, HLA-Cw7, HLA-A1, and D6S2223-177) with an identical extended haplotype in controls. The extended haplotype was present more frequently (35.1% of autoimmune-associated DR3 haplotypes, 39.4% of control DR3 haplotypes) than other haplotypes (no other haplotype >5% of DR3 haplotypes) and remarkably conserved, but it was not transmitted from parents to affected children more frequently than nonconserved DR3-bearing haplotypes. This suggests that if all alleles are truly identical for the major A1, B8, DR3 haplotype (between A1 and DR3), with different alleles on nonconserved haplotypes without differential diabetes risk, then in this region of the genome DR3-DQ2 may be the primary polymorphisms of common haplotypes contributing to diabetes risk.

  6. Successful ABO-Incompatible Renal Transplantation:  Blood Group A1B Donor Into A2B Recipient With Anti-A1 Isoagglutinins.

    PubMed

    Fadeyi, Emmanuel A; Stratta, Robert J; Farney, Alan C; Pomper, Gregory J

    2016-08-01

    Transplantation of the blood group A2B in a recipient was successfully performed in the setting of receiving a deceased donor kidney from an "incompatible" A1B donor. The donor and recipient were both typed for ABO blood group, including ABO genotyping. The donor and recipient were tested for ABO, non-ABO, and human leukocyte antigen (HLA) antibodies. The donor and recipient were typed for HLA antigens, including T- and B-flow cytometry crossmatch tests. The recipient's RBCs were negative with A1 lectin, and immunoglobulin G anti-A1 was demonstrated in the recipient's plasma. The donor-recipient pair was a four-antigen HLA mismatch, but final T- and B-flow cytometry crossmatch tests were compatible. The transplant procedure was uneventful; the patient experienced immediate graft function with no episodes of rejection or readmissions more than 2 years later. It may be safe to transplant across the A1/A2 blood group AB mismatch barrier in the setting of low titer anti-A1 isoagglutinins without the need for pretransplant desensitization even if the antibody produced reacts with anti-human globulin. © American Society for Clinical Pathology, 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  7. Alternative scenarios utilizing nonterrestrial resources

    NASA Technical Reports Server (NTRS)

    Eldred, Charles H.; Roberts, Barney B.

    1992-01-01

    A collection of alternative scenarios that are enabled or substantially enhanced by the utilization of nonterrestrial resources is provided. We take a generalized approach to scenario building so that our report will have value in the context of whatever goals are eventually chosen. Some of the topics covered include the following: lunar materials processing; asteroid mining; lunar resources; construction of a large solar power station; solar dynamic power for the space station; reduced gravity; mission characteristics and options; and tourism.

  8. The sensitivity of fluvial flood risk in Irish catchments to the range of IPCC AR4 climate change scenarios.

    PubMed

    Bastola, Satish; Murphy, Conor; Sweeney, John

    2011-11-15

    In the face of increased flood risk responsible authorities have set out safety margins to incorporate climate change impacts in building robust flood infrastructure. Using the case study of four catchments in Ireland, this study subjects such design allowances to a sensitivity analysis of the uncertainty inherent in estimates of future flood risk. Uncertainty in flood quantiles is quantified using regionalised climate scenarios derived from a large number of GCMs (17), forced with three SRES emissions scenarios. In terms of hydrological response uncertainty within and between hydrological models is assessed using the GLUE framework. Regionalisation is achieved using a change factor method to infer changes in the parameters of a weather generator using monthly output from the GCMs, while flood frequency analysis is conducted using the method of probability weighted moments to fit the Generalised Extreme Value distribution to ~20,000 annual maximia series. Sensitivity results show that for low frequency events, the risk of exceedence of design allowances is greater than for more frequent events, with considerable implications for critical infrastructure. Peak flows for the five return periods assessed were found to be less sensitive to temperature and subsequently to potential evaporation (PET) than to rainfall. The average width of the uncertainty range for changes in flood magnitude is greater for low frequency events than for high frequency events. In all catchments there is a progressive increase in the peak flows associated with the 5, 25, 50 and 100-year return periods when moving from the 2020s to the 2080s.

  9. Assessing hydrologic impacts of future Land Change scenarios in the San Pedro River (U.S./Mexico)

    NASA Astrophysics Data System (ADS)

    Kepner, W. G.; Burns, S.; Sidman, G.; Levick, L.; Goodrich, D. C.; Guertin, P.; Yee, W.; Scianni, M.

    2012-12-01

    An approach was developed to characterize the hydrologic impacts of urban expansion through time for the San Pedro River, a watershed of immense international importance that straddles the U.S./Mexico border. Future urban growth is a key driving force altering local and regional hydrology and is represented by decadal changes in housing density maps from 2010 to 2100 derived from the Integrated Climate and Land-Use Scenarios (ICLUS) database. ICLUS developed future housing density maps by adapting the Intergovernmental Panel on Climate Change (IPCC) Special Report on Emissions Scenarios (SRES) social, economic, and demographic storylines to the conterminous United States. To characterize the hydrologic impacts of future growth, the housing density maps were reclassified to National Land Cover Database 2006 land cover classes and used to parameterize the Soil and Water Assessment Tool (SWAT) using the Automated Geospatial Watershed Assessment (AGWA) tool. The presentation will report 1) the methodology for adapting the ICLUS data for use in AGWA as an approach to evaluate basin-wide impacts of development on water-quantity and -quality, 2) initial results of the application of the methodology, and 3) discuss implications of the analysis.

  10. Do invasive riparian Tamarix alter hydrology of riparian areas of arid and semi-arid regions under climate change scenarios?

    NASA Astrophysics Data System (ADS)

    Bhattarai, M. P.; Acharya, K.; Chen, L.

    2012-12-01

    Competitiveness of riparian invasive species, Tamarix, in arid and semi-arid riparian areas of the southwestern United States under climate change scenario (SRES A2) was investigated. Tamarix has been replacing native vegetation along the riparian corridors of these areas for the past several decades and is thought to alter water balance. Changes in depth to groundwater, soil moisture distribution and flood frequency are critical in survival and growth of a facultative phreatophyte such as Tamarix. In this study, a fully coupled 2d surface flow and 3d subsurface flow hydrologic model, HydroGeoSphere, was used to simulate surface-subsurface hydrology of the lower Virgin River basin (4500 sq. km), located in Nevada, Utah and Arizona. The hydrologic model results, depth to groundwater and soil saturation, were then applied to the species distribution model, Maxent, along with other bioclimatic parameters to asses future Tamarix distribution probability. Simulations were made for the climate scenarios of the end of 21st centry conditions. Depth to groundwater is found to be the most important predictor variable to the Maxent model. Future Tamarix distribution range is not uniform across the basin. It is likely to decrease at lower elevations and increase in some higher elevation areas.

  11. Extreme Climate Event Trends: The Data Mining and Evaluation of the A1FI Scenario for 2000???2100

    SciTech Connect

    Erickson III, David J; Ganguly, Auroop R; Steinhaeuser, Karsten J K; Branstetter, Marcia L; Oglesby, Robert; Hoffman, Forrest M; Buja, Lawrence

    2008-01-01

    The authors discuss the implications and resulting alterations of the hydrologic cycle as Earth climate evolves from 2000-2100. Climate simulations based on the assumptions implicit in the A1F1 scenario for the period 2000-2100 using CCSM3 are analyzed. In particular, we will assess the changes in the surface latent and sensible heat energy budget, the Indian regional water budgets including trends in the timing and duration of the Indian monsoon and the resulting impacts on mean river flow and hydroelectric power generation potential. These analyses will also be examined within the context of heat index, droughts, floods and related estimates of societal robustness and resiliency. We will interpret these new A1F1 results within the context of the previous climate simulations based on the SRES A2 and B1 scenarios forced with land cover and atmospheric CO2. Analyses of historical records in the context of the Indian Monsoon Rainfall (IMR) have suggested an evolving relation of IMR with natural climate variability caused by El Nino events. We will report on the combined effects of natural climate variability and global warming on IMR and assess the trend of extreme rain and temperature events in a warming environment.

  12. Using the New Scenarios Framework to Inform Climate Change Adaptation Policy in Finland

    NASA Astrophysics Data System (ADS)

    Carter, T. R.

    2013-12-01

    In 2005, Finland was among the first countries in the world to develop a national climate change adaptation strategy (Marttila et al., 2005). This included a characterization of future changes in climate and socioeconomic conditions using scenarios based on the IPCC Special Report on Emissions Scenarios (SRES - IPCC, 2000). Following a government evaluation of the strategy, completion of a national adaptation research programme, and in light of the recent European Union adaptation strategy, the Finnish strategy is now under revision. As part of this revision process, the New Scenario Framework (Moss et al., 2010) is being used to guide the mapping of future conditions in Finland out to the end of the 21st century. Future Finnish climate is being analysed using the CMIP5 climate model simulations (Taylor et al., 2012), including downscaled information based on regional climate model projections in the EURO-CORDEX project (Vautard et al., 2013). All projections are forced by the Representative Concentration Pathways (RCPs - van Vuuren et al., 2011). Socioeconomic scenarios are also being developed by outlining alternative pathways that reflect national social, economic, environmental and planning goals. These are designed according to the Shared Socioeconomic Pathway (SSP) framework of challenges to adaptation and mitigation (Kriegler et al., 2012). Work is in progress to characterize these pathways, mainly qualitatively, for different sectors in Finland. Preliminary results of the conceptual scenario development phase will be presented in this session. These initial ideas will be exchanged with representatives of ministries, regional government and key stakeholder groups. The eventual form and number of scenarios that appear in the revised strategy will be determined following a formal review of the draft document to be prepared in 2014. Future work could include quantification of scenarios, possibly mapping them onto the specific SSP worlds. This would then provide

  13. Efficient Maize and Sunflower Multi-year Mapping with NDVI Time Series of HJ-1A/1B in Hetao Irrigation District of Inner Mongolia, China

    NASA Astrophysics Data System (ADS)

    Yu, B.; Shang, S.

    2016-12-01

    Food shortage is one of the major challenges that human beings are facing. It is urgent to improve the monitoring of the plantation and distribution of the main crops to solve the following economic and social issues. Recently, with the extensive use of remote sensing satellite data, it has provided favorable conditions for crop identification in large irrigation district with complex planting structure. Difference of different crop phenology is the main basis for crop identification, and the normalized difference vegetation index (NDVI) time-series could better delineate crop phenology cycle. Therefore, the key of crop identification is to obtain high quality NDVI time-series. MODIS and Landsat TM satellite images are the most frequently used, however, neither of them could guarantee high temporal and spatial resolutions at once. Accordingly, this paper makes use of NDVI time-series extracted from China Environment Satellites data, which has two-day-repeat temporal and 30m spatial resolutions. The NDVI time-series are fitted with an asymmetric logistic curve, the fitting effect is good and the correlation coefficient is greater than 0.9. The phonological parameters are derived from NDVI fitting curves, and crop identification is carried out by different relation ellipses between NDVI and its phonological parameters of different crops. This paper takes Hetao Irrigation District of Inner Mongolia as an example, to identify multi-year maize and sunflower in the district, and the identification result is good. Compared with the official statistics, the relative errors are both lower than 5%. The results show that the NDVI time-series dataset derived from HJ-1A/1B CCD could delineate the crop phenology cycle accurately and demonstrate its application in crop identification in irrigated district.

  14. IgA deficiency and the MHC: assessment of relative risk and microheterogeneity within the HLA A1 B8, DR3 (8.1) haplotype.

    PubMed

    Mohammadi, Javad; Ramanujam, Ryan; Jarefors, Sara; Rezaei, Nima; Aghamohammadi, Asghar; Gregersen, Peter K; Hammarström, Lennart

    2010-01-01

    Selective IgA deficiency (IgAD; serum IgA concentration of <0.07 g/l) is the most common primary immunodeficiency in Caucasians with an estimated prevalence of 1/600. The frequency of the extended major histocompatibility complex haplotype HLA A1, B8, DR3, DQ2 (the "8.1" haplotype) is increased among patients with IgAD. We carried out a direct measurement of the relative risk of homozygosity of the 8.1 haplotype for IgA deficiency in a population-based sample of 117 B8, DR3 homozygous individuals. IgA deficiency was found to be present in 2 of 117 (1.7%) of these subjects, a figure that is concordant with estimates of relative risk from large case-control studies in the Swedish population. These data are consistent with a multiplicative model for the 8.1 haplotype contribution to IgA deficiency and contrasts with prior studies, suggesting a much higher risk for 8.1 homozygosity. Using a dense single nucleotide polymorphism marker analysis of the MHC region in HLA B8, DR3, DQ2 homozygous individuals, we did not observe consistent differences between cases (n = 26) and controls (n = 24). Overall, our results do not support the hypothesis that IgA deficiency is associated with a distinct subgroup of 8.1 related haplotypes, but rather indicate that risk is conferred by the common 8.1 haplotype acting in multiplicative manner.

  15. Role of spinal 5-HT5A, and 5-HT1A/1B/1D, receptors in neuropathic pain induced by spinal nerve ligation in rats.

    PubMed

    Avila-Rojas, Sabino Hazael; Velázquez-Lagunas, Isabel; Salinas-Abarca, Ana Belen; Barragán-Iglesias, Paulino; Pineda-Farias, Jorge Baruch; Granados-Soto, Vinicio

    2015-10-05

    Serotonin (5-HT) participates in pain modulation by interacting with different 5-HT receptors. The role of 5-HT5A receptor in neuropathic pain has not previously studied. The purpose of this study was to investigate: A) the role of 5-HT5A receptors in rats subjected to spinal nerve injury; B) the expression of 5-HT5A receptors in dorsal spinal cord and dorsal root ganglia (DRG). Neuropathic pain was induced by L5/L6 spinal nerve ligation. Tactile allodynia in neuropathic rats was assessed with von Frey filaments. Western blot methodology was used to determine 5-HT5A receptor protein expression. Intrathecal administration (on day 14th) of 5-HT (10-100 nmol) or 5-carboxamidotryptamine (5-CT, 0.03-0.3 nmol) reversed nerve injury-induced tactile allodynia. Intrathecal non-selective (methiothepin, 0.1-0.8 nmol) and selective (SB-699551, 1-10 nmol) 5-HT5A receptor antagonists reduced, by ~60% and ~25%, respectively, the antiallodynic effect of 5-HT (100 nmol) or 5-CT (0.3 nmol). Moreover, both selective 5-HT1A and 5-HT1B/1D receptor antagonists, WAY-100635 (0.3-1 nmol) and GR-127935 (0.3-1 nmol), respectively, partially diminished the antiallodynic effect of 5-HT or 5-CT by about 30%. Injection of antagonists, by themselves, did not affect allodynia. 5-HT5A receptors were expressed in the ipsilateral dorsal lumbar spinal cord and DRG and L5/L6 spinal nerve ligation did not modify 5-HT5A receptor protein expression in those sites. Results suggest that 5-HT5A receptors reduce pain processing in the spinal cord and that 5-HT and 5-CT reduce neuropathic pain through activation of 5-HT5A and 5-HT1A/1B/1D receptors. These receptors could be an important part of the descending pain inhibitory system.

  16. Regional climate change scenarios applied to viticultural zoning in Mendoza, Argentina

    NASA Astrophysics Data System (ADS)

    Cabré, María Fernanda; Quénol, Hervé; Nuñez, Mario

    2016-09-01

    Due to the importance of the winemaking sector in Mendoza, Argentina, the assessment of future scenarios for viticulture is of foremost relevance. In this context, it is important to understand how temperature increase and precipitation changes will impact on grapes, because of changes in grapevine phenology and suitability wine-growing regions must be understood as an indicator of climate change. The general objective is to classify the suitable areas of viticulture in Argentina for the current and future climate using the MM5 regional climate change simulations. The spatial distribution of annual mean temperature, annual rainfall, and some bioclimatic indices has been analyzed for the present (1970-1989) and future (2080-2099) climate under SRES A2 emission scenario. In general, according to projected average growing season temperature and Winkler index classification, the regional model estimates (i) a reduction of cool areas, (ii) a westward and southward displacement of intermediate and warm suitability areas, and (iii) the arise of new suitability regions (hot and very hot areas) over Argentina. In addition, an increase of annual accumulated precipitation is projected over the center-west of Argentina. Similar pattern of change is modeled for growing season, but with lower intensity. Furthermore, the evaluation of projected seasonal precipitation shows a little precipitation increase over Cuyo and center of Argentina in summer and a little precipitation decrease over Cuyo and northern Patagonia in winter. Results show that Argentina has a great potential for expansion into new suitable vineyard areas by the end of twenty-first century, particularly due to projected displacement to higher latitudes for most present suitability winegrowing regions. Even though main conclusions are based on one global-regional model downscaling, this approach provides valuable information for implementing proper and diverse adaptation measures in the Argentinean viticultural

  17. Modeling the potential distribution of Bacillus anthracis under multiple climate change scenarios for Kazakhstan.

    PubMed

    Joyner, Timothy Andrew; Lukhnova, Larissa; Pazilov, Yerlan; Temiralyeva, Gulnara; Hugh-Jones, Martin E; Aikimbayev, Alim; Blackburn, Jason K

    2010-03-09

    Anthrax, caused by the bacterium Bacillus anthracis, is a zoonotic disease that persists throughout much of the world in livestock, wildlife, and secondarily infects humans. This is true across much of Central Asia, and particularly the Steppe region, including Kazakhstan. This study employed the Genetic Algorithm for Rule-set Prediction (GARP) to model the current and future geographic distribution of Bacillus anthracis in Kazakhstan based on the A2 and B2 IPCC SRES climate change scenarios using a 5-variable data set at 55 km(2) and 8 km(2) and a 6-variable BioClim data set at 8 km(2). Future models suggest large areas predicted under current conditions may be reduced by 2050 with the A2 model predicting approximately 14-16% loss across the three spatial resolutions. There was greater variability in the B2 models across scenarios predicting approximately 15% loss at 55 km(2), approximately 34% loss at 8 km(2), and approximately 30% loss with the BioClim variables. Only very small areas of habitat expansion into new areas were predicted by either A2 or B2 in any models. Greater areas of habitat loss are predicted in the southern regions of Kazakhstan by A2 and B2 models, while moderate habitat loss is also predicted in the northern regions by either B2 model at 8 km(2). Anthrax disease control relies mainly on livestock vaccination and proper carcass disposal, both of which require adequate surveillance. In many situations, including that of Kazakhstan, vaccine resources are limited, and understanding the geographic distribution of the organism, in tandem with current data on livestock population dynamics, can aid in properly allocating doses. While speculative, contemplating future changes in livestock distributions and B. anthracis spore promoting environments can be useful for establishing future surveillance priorities. This study may also have broader applications to global public health surveillance relating to other diseases in addition to B. anthracis.

  18. Regional climate change scenarios applied to viticultural zoning in Mendoza, Argentina.

    PubMed

    Cabré, María Fernanda; Quénol, Hervé; Nuñez, Mario

    2016-09-01

    Due to the importance of the winemaking sector in Mendoza, Argentina, the assessment of future scenarios for viticulture is of foremost relevance. In this context, it is important to understand how temperature increase and precipitation changes will impact on grapes, because of changes in grapevine phenology and suitability wine-growing regions must be understood as an indicator of climate change. The general objective is to classify the suitable areas of viticulture in Argentina for the current and future climate using the MM5 regional climate change simulations. The spatial distribution of annual mean temperature, annual rainfall, and some bioclimatic indices has been analyzed for the present (1970-1989) and future (2080-2099) climate under SRES A2 emission scenario. In general, according to projected average growing season temperature and Winkler index classification, the regional model estimates (i) a reduction of cool areas, (ii) a westward and southward displacement of intermediate and warm suitability areas, and (iii) the arise of new suitability regions (hot and very hot areas) over Argentina. In addition, an increase of annual accumulated precipitation is projected over the center-west of Argentina. Similar pattern of change is modeled for growing season, but with lower intensity. Furthermore, the evaluation of projected seasonal precipitation shows a little precipitation increase over Cuyo and center of Argentina in summer and a little precipitation decrease over Cuyo and northern Patagonia in winter. Results show that Argentina has a great potential for expansion into new suitable vineyard areas by the end of twenty-first century, particularly due to projected displacement to higher latitudes for most present suitability winegrowing regions. Even though main conclusions are based on one global-regional model downscaling, this approach provides valuable information for implementing proper and diverse adaptation measures in the Argentinean viticultural

  19. Medical Scenarios Relevant to Spaceflight

    NASA Technical Reports Server (NTRS)

    Bacal, Kira; Hurs, Victor; Doerr, Harold

    2004-01-01

    The Medical Operational Support Team (MOST) was tasked by the JSC Space Medicine and Life Sciences Directorate (SLSD) to incorporate medical simulation into 1) medical training for astronaut-crew medical officers (CMO) and medical flight control teams and 2) evaluations of procedures and resources required for medical care aboard the International Space Station (ISS). Development of evidence-based medical scenarios that mimic the physiology observed during spaceflight will be needed for the MOST to complete these two tasks. The MOST used a human patient simulator, the ISS-like resources in the Medical Simulation Laboratory (MSL), and evidence from space operations, military operations and medical literature to develop space relevant medical scenarios. These scenarios include conditions concerning airway management, Advanced Cardiac Life Support (ACLS) and mitigating anaphylactic symptoms. The MOST has used these space relevant medical scenarios to develop a preliminary space medical training regimen for NASA flight surgeons, Biomedical Flight Controllers (Biomedical Engineers; BME) and CMO-analogs. This regimen is conducted by the MOST in the MSL. The MOST has the capability to develop evidence-based space-relevant medical scenarios that can help SLSD I) demonstrate the proficiency of medical flight control teams to mitigate space-relevant medical events and 2) validate nextgeneration medical equipment and procedures for space medicine applications.

  20. Forecasting the effects of land use scenarios on farmland birds reveal a potential mitigation of climate change impacts.

    PubMed

    Princé, Karine; Lorrillière, Romain; Barbet-Massin, Morgane; Léger, François; Jiguet, Frédéric

    2015-01-01

    Climate and land use changes are key drivers of current biodiversity trends, but interactions between these drivers are poorly modeled, even though they could amplify or mitigate negative impacts of climate change. Here, we attempt to predict the impacts of different agricultural change scenarios on common breeding birds within farmland included in the potential future climatic suitable areas for these species. We used the Special Report on Emissions Scenarios (SRES) to integrate likely changes in species climatic suitability, based on species distribution models, and changes in area of farmland, based on the IMAGE model, inside future climatic suitable areas. We also developed six farmland cover scenarios, based on expert opinion, which cover a wide spectrum of potential changes in livestock farming and cropping patterns by 2050. We ran generalized linear mixed models to calibrate the effects of farmland cover and climate change on bird specific abundance within 386 small agricultural regions. We used model outputs to predict potential changes in bird populations on the basis of predicted changes in regional farmland cover, in area of farmland and in species climatic suitability. We then examined the species sensitivity according to their habitat requirements. A scenario based on extensification of agricultural systems (i.e., low-intensity agriculture) showed the greatest potential to reduce reverse current declines in breeding birds. To meet ecological requirements of a larger number of species, agricultural policies accounting for regional disparities and landscape structure appear more efficient than global policies uniformly implemented at national scale. Interestingly, we also found evidence that farmland cover changes can mitigate the negative effect of climate change. Here, we confirm that there is a potential for countering negative effects of climate change by adaptive management of landscape. We argue that such studies will help inform sustainable

  1. Forecasting the Effects of Land Use Scenarios on Farmland Birds Reveal a Potential Mitigation of Climate Change Impacts

    PubMed Central

    Princé, Karine; Lorrillière, Romain; Barbet-Massin, Morgane; Léger, François; Jiguet, Frédéric

    2015-01-01

    Climate and land use changes are key drivers of current biodiversity trends, but interactions between these drivers are poorly modeled, even though they could amplify or mitigate negative impacts of climate change. Here, we attempt to predict the impacts of different agricultural change scenarios on common breeding birds within farmland included in the potential future climatic suitable areas for these species. We used the Special Report on Emissions Scenarios (SRES) to integrate likely changes in species climatic suitability, based on species distribution models, and changes in area of farmland, based on the IMAGE model, inside future climatic suitable areas. We also developed six farmland cover scenarios, based on expert opinion, which cover a wide spectrum of potential changes in livestock farming and cropping patterns by 2050. We ran generalized linear mixed models to calibrate the effects of farmland cover and climate change on bird specific abundance within 386 small agricultural regions. We used model outputs to predict potential changes in bird populations on the basis of predicted changes in regional farmland cover, in area of farmland and in species climatic suitability. We then examined the species sensitivity according to their habitat requirements. A scenario based on extensification of agricultural systems (i.e., low-intensity agriculture) showed the greatest potential to reduce reverse current declines in breeding birds. To meet ecological requirements of a larger number of species, agricultural policies accounting for regional disparities and landscape structure appear more efficient than global policies uniformly implemented at national scale. Interestingly, we also found evidence that farmland cover changes can mitigate the negative effect of climate change. Here, we confirm that there is a potential for countering negative effects of climate change by adaptive management of landscape. We argue that such studies will help inform sustainable

  2. From molecule to behavior: Brain aromatase (cyp19a1b) characterization, expression analysis and its relation with social status and male agonistic behavior in a Neotropical cichlid fish.

    PubMed

    Ramallo, Martín R; Morandini, Leonel; Birba, Agustina; Somoza, Gustavo M; Pandolfi, Matías

    2017-03-01

    The enzyme aromatase, responsible for the conversion of C19 androgens to C18 estrogens, exists as two paralogue copies in teleost fish: Cyp19a1a mostly expressed in the gonads, referred as gonadal aromatase, and Cyp19a1b, mostly expressed in the brain, accordingly known as brain aromatase. The neural localization of Cyp19a1b is greatly contained within the social behavior network and mesolimbic reward system in fish, suggesting a strong role of estrogen synthesis in the regulation of social behavior. In this work we aimed to analyze the variation in cyp19a1b expression in brain and pituitary of males of a highly social cichlid, Cichlasoma dimerus (locally known as chanchita), and its relation with inter-individual variability in agonistic behavior in a communal social environment. We first characterized chanchita's cyp19a1b mRNA and deduced amino acid sequence, which showed a high degree of conservation when compared to other teleost brain aromatase sequences, and its tissue expression patterns. Within the brain, Cyp19a1b was solely detected at putative radial glial cells of the forebrain, close to the brain ventricles. We then studied the relative expression levels of cyp19a1b by Real Time PCR in the brain and pituitary of males of different social status, territorial vs. non-territorial, and its relationship with an index of agonistic behavior. We found that even though, brain aromatase expression did not differ between types of males, pituitary cyp19a1b expression levels positively correlated with the index of agonistic behavior. This suggests a novel role of the pituitary in the regulation of social behavior by local estrogen synthesis.

  3. Alternative Geothermal Power Production Scenarios

    DOE Data Explorer

    Sullivan, John

    2014-03-14

    The information given in this file pertains to Argonne LCAs of the plant cycle stage for a set of ten new geothermal scenario pairs, each comprised of a reference and improved case. These analyses were conducted to compare environmental performances among the scenarios and cases. The types of plants evaluated are hydrothermal binary and flash and Enhanced Geothermal Systems (EGS) binary and flash plants. Each scenario pair was developed by the LCOE group using GETEM as a way to identify plant operational and resource combinations that could reduce geothermal power plant LCOE values. Based on the specified plant and well field characteristics (plant type, capacity, capacity factor and lifetime, and well numbers and depths) for each case of each pair, Argonne generated a corresponding set of material to power ratios (MPRs) and greenhouse gas and fossil energy ratios.

  4. Hydrological Responses to Land-Use Change Scenarios under Constant and Changed Climatic Conditions

    NASA Astrophysics Data System (ADS)

    Zhang, Ling; Nan, Zhuotong; Yu, Wenjun; Ge, Yingchun

    2016-02-01

    This study quantified the hydrological responses to land-use change scenarios in the upper and middle Heihe River basin (HRB), northwest China, under constant and changed climatic conditions by combining a land-use/cover change model (dynamic conversion of land use and its effects, Dyna-CLUE) and a hydrological model (soil and water assessment tool, SWAT). Five land-use change scenarios, i.e., historical trend (HT), ecological protection (EP), strict ecological protection (SEP), economic development (ED), and rapid economic development (RED) scenarios, were established. Under constant climatic condition, hydrological variations are only induced by land-use changes in different scenarios. The changes in mean streamflow at the outlets of the upper and the middle HRB are not pronounced, although the different scenarios produce different outcomes. However, more pronounced changes are observed on a subbasin level. The frequency of extreme flood is projected to decrease under the SEP scenario, while under the other scenarios, no changes can be found. Two emission scenarios (A1B and B1) of three general circulation models (HadCM3, CGCM3, and CCSM3) were employed to generate future possible climatic conditions. Under changed climatic condition, hydrological variations are induced by the combination of land-use and climatic changes. The results indicate that the impacts of land-use changes become secondary when the changed climatic conditions have been considered. The frequencies of extreme flood and drought are projected to decrease and increase, respectively, under all climate scenarios. Although some agreements can be reached, pronounced difference of hydrological responses can be observed for different climate scenarios of different GCMs.

  5. Hydrological Responses to Land-Use Change Scenarios under Constant and Changed Climatic Conditions.

    PubMed

    Zhang, Ling; Nan, Zhuotong; Yu, Wenjun; Ge, Yingchun

    2016-02-01

    This study quantified the hydrological responses to land-use change scenarios in the upper and middle Heihe River basin (HRB), northwest China, under constant and changed climatic conditions by combining a land-use/cover change model (dynamic conversion of land use and its effects, Dyna-CLUE) and a hydrological model (soil and water assessment tool, SWAT). Five land-use change scenarios, i.e., historical trend (HT), ecological protection (EP), strict ecological protection (SEP), economic development (ED), and rapid economic development (RED) scenarios, were established. Under constant climatic condition, hydrological variations are only induced by land-use changes in different scenarios. The changes in mean streamflow at the outlets of the upper and the middle HRB are not pronounced, although the different scenarios produce different outcomes. However, more pronounced changes are observed on a subbasin level. The frequency of extreme flood is projected to decrease under the SEP scenario, while under the other scenarios, no changes can be found. Two emission scenarios (A1B and B1) of three general circulation models (HadCM3, CGCM3, and CCSM3) were employed to generate future possible climatic conditions. Under changed climatic condition, hydrological variations are induced by the combination of land-use and climatic changes. The results indicate that the impacts of land-use changes become secondary when the changed climatic conditions have been considered. The frequencies of extreme flood and drought are projected to decrease and increase, respectively, under all climate scenarios. Although some agreements can be reached, pronounced difference of hydrological responses can be observed for different climate scenarios of different GCMs.

  6. Haunted Quantum Entanglement: Two Scenarios

    NASA Astrophysics Data System (ADS)

    Snyder, Douglas

    2010-04-01

    Two haunted quantum entanglement scenarios are proposed that are very close to the haunted measurement scenario in that: 1) the entity that is developing as a which-way marker is effectively restored to its state prior to its being fixed as a w-w marker, and 2) the entity for which the developing w-w marker provides information is restored to its state before it interacted with the entity which subsequent to the interaction begins developing as a w-w marker. In the hqe scenarios, the loss of developing w-w information through 1 relies on the loss of a developing entanglement. In scenario 1, the photon initially emitted in one of two micromaser cavities and developing into a w-w marker is effectively lost through the injection of classical microwave radiation into both of the microwave cavities after the atom initially emits the photon into one of the micromaser cavities, exits the cavity system, and before this atom reaches the 2 slit screen. The atom is restored in both of the two new scenarios to its original state before it emitted a photon by an rf coil situated at the exit of the micromaser cavity system. In scenario 2, the cavity system and everything from the atom source forward to the cavity system is enclosed in an evacuated box. After the atom that emits the photon exits the cavity system and before it reaches the 2 slit screen, the cavity system opens (and the photon escapes in the evacuated box) and then the box is opened and the photon escapes into the environment.

  7. [Femicides: concepts, types and scenarios].

    PubMed

    Meneghel, Stela Nazareth; Portella, Ana Paula

    2017-09-01

    This text is a theoretical essay that discusses the concepts, types and scenarios of feminicides, and presents some proposals for the prevention of these premature, unjust and avoidable deaths. The text revisits the original concept of femicide proposed by Diana Russell and Jane Caputti and shows new and old scenarios where these crimes occur. It points to patriarchy, understood as being a hierarchical system of power between men and women, as one of the main determinants of these deaths. It ends by presenting actions and proposals to prevent and combat these gender crimes.

  8. Breadth of neutralization and synergy of clinically relevant human monoclonal antibodies against HCV genotypes 1a, 1b, 2a, 2b, 2c, and 3a.

    PubMed

    Carlsen, Thomas H R; Pedersen, Jannie; Prentoe, Jannick C; Giang, Erick; Keck, Zhen-Yong; Mikkelsen, Lotte S; Law, Mansun; Foung, Steven K H; Bukh, Jens

    2014-11-01

    Human monoclonal antibodies (HMAbs) with neutralizing capabilities constitute potential immune-based treatments or prophylaxis against hepatitis C virus (HCV). However, lack of cell culture-derived HCV (HCVcc) harboring authentic envelope proteins (E1/E2) has hindered neutralization investigations across genotypes, subtypes, and isolates. We investigated the breadth of neutralization of 10 HMAbs with therapeutic potential against a panel of 16 JFH1-based HCVcc-expressing patient-derived Core-NS2 from genotypes 1a (strains H77, TN, and DH6), 1b (J4, DH1, and DH5), 2a (J6, JFH1, and T9), 2b (J8, DH8, and DH10), 2c (S83), and 3a (S52, DBN, and DH11). Virus stocks used for in vitro neutralization analysis contained authentic E1/E2, with the exception of full-length JFH1 that acquired the N417S substitution in E2. The 50% inhibition concentration (IC50) for each HMAb against the HCVcc panel was determined by dose-response neutralization assays in Huh7.5 cells with antibody concentrations ranging from 0.0012 to 100 μg/mL. Interestingly, IC50 values against the different HCVcc's exhibited large variations among the HMAbs, and only three HMAbs (HC-1AM, HC84.24, and AR4A) neutralized all 16 HCVcc recombinants. Furthermore, the IC50 values for a given HMAb varied greatly with the HCVcc strain, which supports the use of a diverse virus panel. In cooperation analyses, HMAbs HC84.24, AR3A, and, especially HC84.26, demonstrated synergistic effects towards the majority of the HCVcc's when combined individually with AR4A. Through a neutralization analysis of 10 clinically relevant HMAbs against 16 JFH1-based Core-NS2 recombinants from genotypes 1a, 1b, 2a, 2b, 2c, and 3a, we identified at least three HMAbs with potent and broad neutralization potential. The neutralization synergism obtained when pooling the most potent HMAbs could have significant implications for developing novel strategies to treat and control HCV. © 2014 by the American Association for the Study of Liver

  9. Temperature humidity index scenarios in the Mediterranean basin

    NASA Astrophysics Data System (ADS)

    Segnalini, M.; Bernabucci, U.; Vitali, A.; Nardone, A.; Lacetera, N.

    2013-05-01

    The study was undertaken to describe the temperature humidity index (THI) dynamics over the Mediterranean basin for the period 1971-2050. The THI combines temperature and humidity into a single value, and has been widely used to predict the effects of environmental warmth in farm animals. The analysis was based on daily outputs of the temperature and relative humidity from the Max Planck Institute data using the Intergovernmental Panel on Climate Change Special Report Emission Scenario A1B. Data revealed a gradual increase of both annual and seasonal THI during the period under investigation and a strong heterogeneity of the Mediterranean area. In particular, the analysis indicated that Spain, southern France and Italy should be expected to undergo the highest THI increase, which in the last decade under study (2041-2050) will range between 3 and 4 units. However, only during summer months the area presents characteristics indicating risk of thermal (heat) stress for farm animals. In this regard, scenario maps relative to the summer season suggested an enlargement of the areas in the basin where summer THI values will likely cause thermal discomfort in farm animals. In conclusion, the study indicated that the Mediterranean basin is likely to undergo THI changes, which may aggravate the consequences of hot weather on animal welfare, performances, health and survival and may help farmers, nutritionists, veterinarians, and policy-makers to develop appropriate adaptation strategies to limit consequences of climate change for the livestock sector in the Mediterranean countries.

  10. Particle production in Ekpyrotic scenarios

    SciTech Connect

    Hipólito-Ricaldi, W.S.; Brandenberger, Robert; Ferreira, Elisa G.M.; Graef, L.L.

    2016-11-09

    We consider Parker particle production in the Ekpyrotic scenario (in particular in the New Ekpyrotic model) and show that the density of particles produced by the end of the phase of Ekpyrotic contraction can be sufficient to lead to a hot state of matter after the bounce. Hence, no separate reheating mechanism is necessary.

  11. Space resources. Volume 1: Scenarios

    NASA Technical Reports Server (NTRS)

    Mckay, Mary Fae (Editor); Mckay, David S. (Editor); Duke, Michael B. (Editor)

    1992-01-01

    A number of possible future paths for space exploration and development are presented. The topics covered include the following: (1) the baseline program; (2) alternative scenarios utilizing nonterrestrial resources; (3) impacts of sociopolitical conditions; (4) common technologies; and issues for further study.

  12. Future Scenarios and Environmental Education

    ERIC Educational Resources Information Center

    Kopnina, Helen

    2014-01-01

    This article explores a number of questions about visions of the future and their implications for environmental education (EE). If the future were known, what kind of actions would be needed to maintain the positive aspects and reverse the negative ones? How could these actions be translated into the aims of EE? Three future scenarios are…

  13. Ultra-Perfect Sorting Scenarios

    NASA Astrophysics Data System (ADS)

    Ouangraoua, Aïda; Bergeron, Anne; Swenson, Krister M.

    Perfection has been used as a criteria to select rearrangement scenarios since 2004. However, there is a fundamental bias towards extant species in the original definition: ancestral species are not bound to perfection. Here we develop a new theory of perfection that takes an egalitarian view of species, and apply it to the complex evolution of mammal chromosome X.

  14. Transportation scenarios for risk analysis.

    SciTech Connect

    Weiner, Ruth F.

    2010-09-01

    Transportation risk, like any risk, is defined by the risk triplet: what can happen (the scenario), how likely it is (the probability), and the resulting consequences. This paper evaluates the development of transportation scenarios, the associated probabilities, and the consequences. The most likely radioactive materials transportation scenario is routine, incident-free transportation, which has a probability indistinguishable from unity. Accident scenarios in radioactive materials transportation are of three different types: accidents in which there is no impact on the radioactive cargo, accidents in which some gamma shielding may be lost but there is no release of radioactive material, and accident in which radioactive material may potentially be released. Accident frequencies, obtainable from recorded data validated by the U.S. Department of Transportation, are considered equivalent to accident probabilities in this study. Probabilities of different types of accidents are conditional probabilities, conditional on an accident occurring, and are developed from event trees. Development of all of these probabilities and the associated highway and rail accident event trees are discussed in this paper.

  15. Assessing Hydrologic Impacts of Future Land Cover Change Scenarios in the South Platte River Basin (CO, WY, & NE) and the San Pedro River Basin (U.S./Mexico).

    NASA Astrophysics Data System (ADS)

    Barlow, J. E.; Burns, I. S.; Guertin, D. P.; Kepner, W. G.; Goodrich, D. C.

    2016-12-01

    Long-term land-use and land cover change and their associated impacts pose critical challenges to sustaining vital hydrological ecosystem services for future generations. In this study, a methodology to characterize hydrologic impacts from future urban growth through time that was developed and applied on the San Pedro River Basin was expanded and utilized on the South Platte River Basin as well. Future urban growth is represented by housing density maps generated in decadal intervals from 2010 to 2100, produced by the U.S. Environmental Protection Agency (EPA) Integrated Climate and Land-Use Scenarios (ICLUS) project. ICLUS developed future housing density maps by adapting the Intergovernmental Panel on Climate Change (IPCC) Special Report on Emissions Scenarios (SRES) social, economic, and demographic storylines to the conterminous United States. To characterize hydrologic impacts from future growth, the housing density maps were reclassified to National Land Cover Database (NLCD) 2006 land cover classes and used to parameterize the Soil and Water Assessment Tool (SWAT) using the Automated Geospatial Watershed Assessment (AGWA) tool. The objectives of this project were to 1) develop and implement a methodology for adapting the ICLUS data for use in AGWA as an approach to evaluate impacts of development on water-quantity and -quality, 2) present, evaluate, and compare results from scenarios for watersheds in two different geographic and climatic regions, 3) determine watershed specific implications of this type of future land cover change analysis.

  16. 2014-2016 Mt. Etna Ground deformation imaged by SISTEM approach using GPS and SENTINEL-1A/1B TOPSAR data

    NASA Astrophysics Data System (ADS)

    Bonforte, Alessandro; Guglielmino, Francesco; Puglisi, Giuseppe

    2017-04-01

    In the frame of the EC FP7 MED-SUV project (call FP7 ENV.2012.6.4-2), and thanks to the GEO-GSNL initiative, GPS data and SENTINEL 1A/1B TOPSAR acquired on Mt. Etna between October 2014 and November 2016 were analyzed. The SENTINEL data were used in order to combine and integrate them with GPS, and detail the ground deformation recorded by GPS on Mt. Etna, during the last two-year's volcanic activity. The Sentinel data were processed by GAMMA software, using a spectral diversity method and a procedure able to co-register the SENTINEL pairs with extremely high precision (< 0.01 pixel). In order to optimize the time processing, a new software architecture based on the hypervisor virtualization technology for the x64 versions of Windows has been implemented. The DInSAR results are analysed and successively used as input for the time series analysis using the StaMPS package. On December 28, 2014 eruptive activity resumed at Mt. Etna with a fire fountain activity feeding two lava flows spreading on the eastern and south-western upper flanks of the volcano, producing evident deformation at the summit of the volcano. GPS displacements and Sentinel-1A ascending interferogram were calculated in order to image the ground deformation pattern accompanying the eruption. The ground deformation pattern has been perfectly depicted by the GPS network, mainly affecting the uppermost part of the volcano edifice, with a strong decay of the deformation, according to a very shallow and strong dyke intrusion. The Sentinel 1A SAR data, covering the similar time spanning, confirmed that most of displacements are related to the dike intrusion, and evidenced a local gravity-driven motion of the western wall of the Valle del Bove, probably related to the dike intrusion. To monitor the temporal successive evolution of ground deformation, we performed an A-DInSAR SENTINEL analysis using the Small BAseline Subset (SBAS) approach included with the StaMPS processing package. The April 2015

  17. Exploring NASA Human Spaceflight and Pioneering Scenarios

    NASA Technical Reports Server (NTRS)

    Zapata, Edgar; Wilhite, Alan

    2015-01-01

    The life cycle cost analysis of space exploration scenarios is explored via a merger of (1) scenario planning, separating context and (2) modeling and analysis of specific content. Numerous scenarios are presented, leading to cross-cutting recommendations addressing life cycle costs, productivity, and approaches applicable to any scenarios. Approaches address technical and non-technical factors.

  18. A Native American exposure scenario.

    PubMed

    Harris, S G; Harper, B L

    1997-12-01

    EPA's Risk Assessment Guidance for Superfund (RAGS) and later documents provide guidance for estimating exposures received from suburban and agricultural activity patterns and lifestyles. However, these methods are not suitable for typical tribal communities whose members pursue, at least in part, traditional lifestyles. These lifestyles are derived from a long association with all of the resources in a particular region. We interviewed 35 members of a Columbia River Basin tribe to develop a lifestyle-based subsistence exposure scenario that represents a midrange exposure that a traditional tribal member would receive. This scenario provides a way to partially satisfy Executive Order 12,898 on environmental justice, which requires a specific evaluation of impacts from federal actions to peoples with subsistence diets. Because a subsistence diet is only a portion of what is important to a traditional lifestyle, we also used information obtained from the interviews to identify parameters for evaluating impacts to environmental and sociocultural quality of life.

  19. [Eukaryotes origin: a new scenario].

    PubMed

    Gonchikov, G G

    2010-01-01

    A new scenario of eukaryotes origin is proposed that explains the cytoskeleton genesis, and the genesis of cell nucleus as a "cell within cell" structure. The scenario is based on the peculiarities of spore-forming firmicutes life cycle and structure, unique for prokaryotes. It is supposed that a euryarchaeon cell was engulfed by a "bare" sporangium of an ancient polyendosporogenic and endoskeletal clostridia, bearer of microtubular endospore appendages, in the process of "abortive" forespore engulfment. In the result, a new driving force for cell transitions was formed, associated with compartmentalization of prokaryotic chromosomes. Further recombination of chromosomes induced two transitions: transformation of euryarchaeon into true cell nucleus, and transformation of microtubular endospore appendages into nucleus mitotic apparatus. In-cell reproducing organelles, such as mitochondrion and plastids, appeared later. Forthcoming full-genome studies of endoskeletal firmicutes, bearers of microtubular endospore appendages, and some eukaryotes may help to reveal the mystery of the first true nuclear cell origin.

  20. Change of soil carbon fluxes in European beech forest under different climate and management scenarios: an example from Serbia

    NASA Astrophysics Data System (ADS)

    Stojanović, Dejan; Orlović, Saša; Matović, Bratislav; Suckow, Felicitas; Lasch-Born, Petra; Galić, Zoran; Reyer, Christopher; Gutsch, Martin; Pekeč, Saša

    2013-04-01

    Soil texture and structure, rainfall, temperature conditions and forest management determine the rate of soil carbon sequestration in forest ecosystems. European beech is one of most important and most abundant tree species in Europe. Forest management strategy influences aboveground biomass as well as belowground biomass and soil organic and inorganic carbon. This study explores how different management strategies (i.e. thinning from above intensities with 10%, 20% and 30% removal of trees every ten years) under three different time periods 1971-2000, 2011-2040 and 2051-2080 of the IPCC SRES A2 climate change scenario, influence total soil carbon stock in a beech stand in eastern Serbia. For the simulations, the process-based tree growth model 4C was used. At the beginning of the simulations, the total soil carbon stock was about 85 tC/ha. The most intensive management strategy appears to provide highest carbon fluxes into the soil and the highest total carbon stock values (between 160 and 180 tC/ha) at the end of the simulation periods. All management strategies under the climate of the period 2051-2080 showed the lowest values (about 160 tC/ha). We analyse the interrelationships between management caused changes in litter fluxes and climate (mainly temperature) caused losses of carbon from soil by respiration. In some cases different thinning intensities showed similar fluxes for the same time periods, whereas both climate scenario periods showed quite similar influence for the same management scenarios. The influence of different management strategies on the final total soil carbon stock will be shown.

  1. Designing Asteroid Impact Scenario Trajectories

    NASA Astrophysics Data System (ADS)

    Chodas, Paul

    2016-05-01

    In order to study some of the technical and geopolitical issues of dealing with an asteroid on impact trajectory, a number of hypothetical impact scenarios have been presented over the last ten years or so. These have been used, for example, at several of the Planetary Defense Conferences (PDCs), as well as in tabletop exercises with the Federal Emergency Management Agency (FEMA), along with other government agencies. The exercise at the 2015 PDC involved most of the attendees, consisted of seven distinct steps (“injects”), and with all the presentations and discussions, took up nearly 10 hours of conference time. The trajectory for the PDC15 scenario was entirely realistic, and was posted ahead of the meeting. It was made available in the NEO Program’s Horizons ephemeris service so that users could , for example, design their own deflection missions. The simulated asteroid and trajectory had to meet numerous very exacting requirements: becoming observable on the very first day of the conference, yet remaining very difficult to observe for the following 7 years, and far enough away from Earth that it was out of reach of radar until just before impact. It had to be undetectable in the past, and yet provide multiple perihelion opportunities for deflection in the future. It had to impact in a very specific region of the Earth, a specific number of years after discovery. When observations of the asteroid are simulated to generate an uncertainty region, that entire region must impact the Earth along an axis that cuts across specific regions of the Earth, the “risk corridor”. This is important because asteroid deflections generally move an asteroid impact point along this corridor. One scenario had a requirement that the asteroid pass through a keyhole several years before impact. The PDC15 scenario had an additional constraint that multiple simulated kinetic impactor missions altered the trajectory at a deflection point midway between discovery and impact

  2. Brain aromatase (cyp19a1b) and gonadotropin releasing hormone (gnrh2 and gnrh3) expression during reproductive development and sex change in black sea bass (Centropristis striata).

    PubMed

    Breton, Timothy S; DiMaggio, Matthew A; Sower, Stacia A; Berlinsky, David L

    2015-03-01

    Teleost fish exhibit diverse reproductive strategies, and some species are capable of changing sex. The influence of many endocrine factors, such as gonadal steroids and neuropeptides, has been studied in relation to sex change, but comparatively less research has focused on gene expression changes within the brain in temperate grouper species with non-haremic social structures. The purpose of the present study was to investigate gonadotropin releasing hormone (GnRH) and brain aromatase (cyp19a1b) gene expression patterns during reproductive development and sex change in protogynous (female to male) black sea bass (Centropristis striata). Partial cDNA fragments for cyp19a1b and eef1a (a reference gene) were identified, and included with known gnrh2 and gnrh3 sequences in real time quantitative PCR. Elevated cyp19a1b expression was evident in the olfactory bulbs, telencephalon, optic tectum, and hypothalamus/midbrain region during vitellogenic growth, which may indicate changes in the brain related to neurogenesis or sexual behavior. In contrast, gnrh2 and gnrh3 expression levels were largely similar among gonadal states, and all three genes exhibited stable expression during sex change. Although sex change in black sea bass is not associated with dramatic changes in GnRH or cyp19a1b gene expression among brain regions, these genes may mediate processes at other levels, such as within individual hypothalamic nuclei, or through changes in neuron size, that warrant further research.

  3. Human natural killer cell microRNA: differential expression of MIR181A1B1 and MIR181A2B2 genes encoding identical mature microRNAs.

    PubMed

    Presnell, S R; Al-Attar, A; Cichocki, F; Miller, J S; Lutz, C T

    2015-01-01

    Natural killer (NK) and T lymphocytes share many properties, yet only NK cells respond rapidly to infection and cancer without pre-activation. We found that few microRNAs (miRNAs) differed significantly between human NK and T cells. Among those miRNAs, miR-181a and miR-181b levels rose during NK cell differentiation. Prior studies indicate that miR-181a and miR-181b are critical for human NK cell development and are co-transcribed from genes on chromosome 1 (MIR181A1B1) and on chromosome 9 (MIR181A2B2). We mapped human MIR181A1B1 and MIR181A2B2 transcription start sites to 78.3 kb and 34.0 kb upstream of the mature miRNAs, generating predominantly unspliced transcripts of 80-127 kb and ~60 kb, respectively. Unlike mouse thymocytes, human T cells expressed both MIR181A1B1 and MIR181A2B2. We tested the hypothesis that NK cells differentially transcribe the two genes during development and in response to immune regulatory cytokines. During NK-cell differentiation, MIR181A2B2 expression rose markedly and exceeded that of MIR181A1B1. TGF-β treatment increased NK-cell MIR181A2B2 transcription, whereas IL-2, IL-15 and IL-12/IL-18 treatments upregulated MIR181A1B1. The MIR181A2B2 promoter was strongly transactivated by SMAD3 and SMAD4 transcription factors, suggesting that TGF-β signaling upregulates MIR181A2B2 expression, at least in part, through SMAD-dependent promoter activation.

  4. Future scenarios of land-use and land-cover change in the United States--the Marine West Coast Forests Ecoregion

    USGS Publications Warehouse

    Wilson, Tamara S.; Sleeter, Benjamin M.; Sohl, Terry L.; Griffith, Glenn; Acevedo, William; Bennett, Stacie; Bouchard, Michelle; Reker, Ryan; Ryan, Christy; Sayler, Kristi L.; Sleeter, Rachel; Soulard, Christopher E.

    2012-01-01

    Detecting, quantifying, and projecting historical and future changes in land use and land cover (LULC) has emerged as a core research area for the U.S. Geological Survey (USGS). Changes in LULC are important drivers of changes to biogeochemical cycles, the exchange of energy between the Earth’s surface and atmosphere, biodiversity, water quality, and climate change. To quantify the rates of recent historical LULC change, the USGS Land Cover Trends project recently completed a unique ecoregion-based assessment of late 20th century LULC change for the western United States. To characterize present LULC, the USGS and partners have created the National Land Cover Database (NLCD) for the years 1992, 2001, and 2006. Both Land Cover Trends and NLCD projects continue to evolve in an effort to better characterize historical and present LULC conditions and are the foundation of the data presented in this report. Projecting future changes in LULC requires an understanding of the rates and patterns of change, the major driving forces, and the socioeconomic and biophysical determinants and capacities of regions. The data presented in this report is the result of an effort by USGS scientists to downscale the Intergovernmental Panel on Climate Change (IPCC) Special Report on Emission Scenarios (SRES) to ecoregions of the conterminous United States as part of the USGS Biological Carbon Sequestration Assessment. The USGS biological carbon assessment was mandated by Section 712 of the Energy Independence and Security Act of 2007. As part of the legislative mandate, the USGS is required to publish a methodology describing, in detail, the approach to be used for the assessment. The development of future LULC scenarios is described in chapter 3.2 and appendix A. Spatial modeling is described in chapter 3.3.2 and appendix B and in Sohl and others (2011). In this report, we briefly summarize the major components and methods used to downscale IPCC-SRES scenarios to ecoregions of the

  5. Europa Explorer Operational Scenarios Development

    NASA Technical Reports Server (NTRS)

    Lock, Robert E.; Pappalardo, Robert T.; Clark, Karla B.

    2008-01-01

    In 2007, NASA conducted four advanced mission concept studies for outer planets targets: Europa, Ganymede, Titan and Enceladus. The studies were conducted in close cooperation with the planetary science community. Of the four, the Europa Explorer Concept Study focused on refining mission options, science trades and implementation details for a potential flagship mission to Europa in the 2015 timeframe. A science definition team (SDT) was appointed by NASA to guide the study. A JPL-led engineering team worked closely with the science team to address 3 major focus areas: 1) credible cost estimates, 2) rationale and logical discussion of radiation risk and mitigation approaches, and 3) better definition and exploration of science operational scenario trade space. This paper will address the methods and results of the collaborative process used to develop Europa Explorer operations scenarios. Working in concert with the SDT, and in parallel with the SDT's development of a science value matrix, key mission capabilities and constraints were challenged by the science and engineering members of the team. Science goals were advanced and options were considered for observation scenarios. Data collection and return strategies were tested via simulation, and mission performance was estimated and balanced with flight and ground system resources and science priorities. The key to this successful collaboration was a concurrent development environment in which all stakeholders could rapidly assess the feasibility of strategies for their success in the full system context. Issues of science and instrument compatibility, system constraints, and mission opportunities were treated analytically and objectively leading to complementary strategies for observation and data return. Current plans are that this approach, as part of the system engineering process, will continue as the Europa Explorer Concept Study moves toward becoming a development project.

  6. Spent fuel receipt scenarios study

    SciTech Connect

    Ballou, L.B.; Montan, D.N.; Revelli, M.A.

    1990-09-01

    This study reports on the results of an assignment from the DOE Office of Civilian Radioactive Waste Management to evaluate of the effects of different scenarios for receipt of spent fuel on the potential performance of the waste packages in the proposed Yucca Mountain high-level waste repository. The initial evaluations were performed and an interim letter report was prepared during the fall of 1988. Subsequently, the scope of work was expanded and additional analyses were conducted in 1989. This report combines the results of the two phases of the activity. This study is a part of a broader effort to investigate the options available to the DOE and the nuclear utilities for selection of spent fuel for acceptance into the Federal Waste Management System for disposal. Each major element of the system has evaluated the effects of various options on its own operations, with the objective of providing the basis for performing system-wide trade-offs and determining an optimum acceptance scenario. Therefore, this study considers different scenarios for receipt of spent fuel by the repository only from the narrow perspective of their effect on the very-near-field temperatures in the repository following permanent closure. This report is organized into three main sections. The balance of this section is devoted to a statement of the study objective, a summary of the assumptions. The second section of the report contains a discussion of the major elements of the study. The third section summarizes the results of the study and draws some conclusions from them. The appendices include copies of the waste acceptance schedule and the existing and projected spent fuel inventory that were used in the study. 10 refs., 27 figs.

  7. Europa Explorer Operational Scenarios Development

    NASA Technical Reports Server (NTRS)

    Lock, Robert E.; Pappalardo, Robert T.; Clark, Karla B.

    2008-01-01

    In 2007, NASA conducted four advanced mission concept studies for outer planets targets: Europa, Ganymede, Titan and Enceladus. The studies were conducted in close cooperation with the planetary science community. Of the four, the Europa Explorer Concept Study focused on refining mission options, science trades and implementation details for a potential flagship mission to Europa in the 2015 timeframe. A science definition team (SDT) was appointed by NASA to guide the study. A JPL-led engineering team worked closely with the science team to address 3 major focus areas: 1) credible cost estimates, 2) rationale and logical discussion of radiation risk and mitigation approaches, and 3) better definition and exploration of science operational scenario trade space. This paper will address the methods and results of the collaborative process used to develop Europa Explorer operations scenarios. Working in concert with the SDT, and in parallel with the SDT's development of a science value matrix, key mission capabilities and constraints were challenged by the science and engineering members of the team. Science goals were advanced and options were considered for observation scenarios. Data collection and return strategies were tested via simulation, and mission performance was estimated and balanced with flight and ground system resources and science priorities. The key to this successful collaboration was a concurrent development environment in which all stakeholders could rapidly assess the feasibility of strategies for their success in the full system context. Issues of science and instrument compatibility, system constraints, and mission opportunities were treated analytically and objectively leading to complementary strategies for observation and data return. Current plans are that this approach, as part of the system engineering process, will continue as the Europa Explorer Concept Study moves toward becoming a development project.

  8. Differentiating the effects of climate and land use change on European biodiversity: A scenario analysis.

    PubMed

    Vermaat, Jan E; Hellmann, Fritz A; van Teeffelen, Astrid J A; van Minnen, Jelle; Alkemade, Rob; Billeter, Regula; Beierkuhnlein, Carl; Boitani, Luigi; Cabeza, Mar; Feld, Christian K; Huntley, Brian; Paterson, James; WallisDeVries, Michiel F

    2017-04-01

    Current observed as well as projected changes in biodiversity are the result of multiple interacting factors, with land use and climate change often marked as most important drivers. We aimed to disentangle the separate impacts of these two for sets of vascular plant, bird, butterfly and dragonfly species listed as characteristic for European dry grasslands and wetlands, two habitats of high and threatened biodiversity. We combined articulations of the four frequently used SRES climate scenarios and associated land use change projections for 2030, and assessed their impact on population trends in species (i.e. whether they would probably be declining, stable or increasing). We used the BIOSCORE database tool, which allows assessment of the effects of a range of environmental pressures including climate change as well as land use change. We updated the species lists included in this tool for our two habitat types. We projected species change for two spatial scales: the EU27 covering most of Europe, and the more restricted biogeographic region of 'Continental Europe'. Other environmental pressures modelled for the four scenarios than land use and climate change generally did not explain a significant part of the variance in species richness change. Changes in characteristic bird and dragonfly species were least pronounced. Land use change was the most important driver for vascular plants in both habitats and spatial scales, leading to a decline in 50-100% of the species included, whereas climate change was more important for wetland dragonflies and birds (40-50 %). Patterns of species decline were similar in continental Europe and the EU27 for wetlands but differed for dry grasslands, where a substantially lower proportion of butterflies and birds declined in continental Europe, and 50 % of bird species increased, probably linked to a projected increase in semi-natural vegetation. In line with the literature using climate envelope models, we found little divergence

  9. Change in statistics of drought in a land use scenario for Brazil

    NASA Astrophysics Data System (ADS)

    Kilian, Markus; Chavez, Erik; Lucarini, Valerio

    2016-04-01

    The land use changes due to an intensified and expanding agricultural and industrial activity is affecting regional weather and climate in Brazil. We analyse the results of a land use change driven Weather and Research Forecasting Model (WRF) using classical drought indices and specific agricultural yield loss drought optimum indices. The objective is to assess changes in risk exposure driven by changes in weather patterns subject to different scenarios of land use changes in Brazil. The WRF model is driven by land use changes as well as the ECHAM5 climate model (with the A1B scenario) on a 60km and 30km grid. In order to determine the risk exposure of an important economic sector to changes in land use change we focus on maize as one of the principal crop grown in Brazil.

  10. Scenarios for coastal vulnerability assessment

    USGS Publications Warehouse

    Nicholls, Robert J.; Woodroffe, Colin D.; Burkett, Virginia; Hay, John; Wong, Poh Poh; Nurse, Leonard; Wolanski, Eric; McLusky, Donald S.

    2011-01-01

    Coastal vulnerability assessments tend to focus mainly on climate change and especially on sea-level rise. Assessment of the influence of nonclimatic environmental change or socioeconomic change is less well developed and these drivers are often completely ignored. Given that the most profound coastal changes of the twentieth century due to nonclimate drivers are likely to continue through the twenty-first century, this is a major omission. It may result in not only overstating the importance of climate change but also overlooking significant interactions of climate change and other drivers. To support the development of policies relating to climate change and coastal management, integrated assessments of climatic change in coastal areas are required, including the effects of all the relevant drivers. This chapter explores the development of scenarios (or "plausible futures") of relevant climate and nonclimate drivers that can be used for coastal analysis, with an emphasis on the nonclimate drivers. It shows the importance of analyzing the impacts of climate change and sea-level rise in a broader context of coastal change and all its drivers. This will improve the analysis of impacts, key vulnerabilities, and adaptation needs and, hence, inform climate and coastal policy. Stakeholder engagement is important in the development of scenarios, and the underlying assumptions need to be explicit, transparent, and open to scientific debate concerning their uncertainties/realism and likelihood.

  11. Scenario Development for the Southwestern United States

    NASA Astrophysics Data System (ADS)

    Mahmoud, M.; Gupta, H.; Stewart, S.; Liu, Y.; Hartmann, H.; Wagener, T.

    2006-12-01

    The primary goal of employing a scenario development approach for the U.S. southwest is to inform regional policy by examining future possibilities related to regional vegetation change, water-leasing, and riparian restoration. This approach is necessary due to a lack of existing explicit water resources application of scenarios to the entire southwest region. A formal approach for scenario development is adopted and applied towards water resources issues within the arid and semi-arid regions of the U.S. southwest following five progressive and reiterative phases: scenario definition, scenario construction, scenario analysis, scenario assessment, and risk management. In the scenario definition phase, the inputs of scientists, modelers, and stakeholders were collected in order to define and construct relevant scenarios to the southwest and its water sustainability needs. From stakeholder-driven scenario workshops and breakout sessions, the three main axes of principal change were identified to be climate change, population development patterns, and quality of information monitoring technology. Based on the extreme and varying conditions of these three main axes, eight scenario narratives were drafted to describe the state of each scenario's respective future and the events which led to it. Events and situations are described within each scenario narrative with respect to key variables; variables that are both important to regional water resources (as distinguished by scientists and modelers), and are good tracking and monitoring indicators of change. The current phase consists of scenario construction, where the drafted scenarios are re-presented to regional scientists and modelers to verify that proper key variables are included (or excluded) from the eight narratives. The next step is to construct the data sets necessary to implement the eight scenarios on the respective computational models of modelers investigating vegetation change, water-leasing, and riparian

  12. Development and Change through Scenario Planning

    ERIC Educational Resources Information Center

    Chermack, Thomas J.; Walton, John S.

    2004-01-01

    This paper examines the role of scenario planning as a development and change intervention. To do so, this article provides an overview of scenario planning and an overview of development and change in organizations. The article then builds on the philosophical orientations of development and change through scenario planning introducing the…

  13. South African maize production scenarios for 2055 using a combined empirical and process-based model approach

    NASA Astrophysics Data System (ADS)

    Estes, L.; Bradley, B.; Oppenheimer, M.; Wilcove, D.; Beukes, H.; Schulze, R. E.; Tadross, M.

    2011-12-01

    In South Africa, a semi-arid country with a diverse agricultural sector, climate change is projected to negatively impact staple crop production. Our study examines future impacts to maize, South Africa's most widely grown staple crop. Working at finer spatial resolution than previous studies, we combine the process-based DSSAT4.5 and the empirical MAXENT models to study future maize suitability. Climate scenarios were based on 9 GCMs run under SRES A2 and B1 emissions scenarios down-scaled (using self-organizing maps) to 5838 locations. Soil properties were derived from textural and compositional data linked to 26422 landforms. DSSAT was run with typical dryland planting parameters and mean projected CO2 values. MAXENT was trained using aircraft-observed distributions and monthly climatologies data derived from downscaled daily records, with future rainfall increased by 10% to simulate CO2 related water-use efficiency gains. We assessed model accuracy based on correlations between model output and a satellite-derived yield proxy (integrated NDVI), and the overlap of modeled and observed maize field distributions. DSSAT yields were linearly correlated to mean integrated NDVI (R2 = 0.38), while MAXENT's relationship was logistic. Binary suitability maps based on thresholding model outputs were slightly more accurate for MAXENT (88%) than for DSSAT (87%) when compared to current maize field distribution. We created 18 suitability maps for each model (9 GCMs X 2 SRES) using projected changes relative to historical suitability thresholds. Future maps largely agreed in eastern South Africa, but disagreed strongly in the semi-arid west. Using a 95% confidence criterion (17 models agree), MAXENT showed a 241305 km2 suitability loss relative to its modeled historical suitability, while DSSAT showed a potential loss of only 112446 km2. Even the smaller potential loss highlighted by DSSAT is uncertain, given that DSSAT's mean (across all 18 climate scenarios) projected yield

  14. The ShakeOut Scenario

    USGS Publications Warehouse

    Jones, Lucile M.; Bernknopf, Richard; Cox, Dale; Goltz, James; Hudnut, Kenneth; Mileti, Dennis; Perry, Suzanne; Ponti, Daniel; Porter, Keith; Reichle, Michael; Seligson, Hope; Shoaf, Kimberley; Treiman, Jerry; Wein, Anne

    2008-01-01

    This is the initial publication of the results of a cooperative project to examine the implications of a major earthquake in southern California. The study comprised eight counties: Imperial, Kern, Los Angeles, Orange, Riverside, San Bernardino, San Diego, and Ventura. Its results will be used as the basis of an emergency response and preparedness exercise, the Great Southern California ShakeOut, and for this purpose we defined our earthquake as occurring at 10:00 a.m. on November 13, 2008. As members of the southern California community use the ShakeOut Scenario to plan and execute the exercise, we anticipate discussion and feedback. This community input will be used to refine our assessment and will lead to a formal publication in early 2009. Our goal in the ShakeOut Scenario is to identify the physical, social and economic consequences of a major earthquake in southern California and in so doing, enable the users of our results to identify what they can change now?before the earthquake?to avoid catastrophic impact after the inevitable earthquake occurs. To do so, we had to determine the physical damages (casualties and losses) caused by the earthquake and the impact of those damages on the region?s social and economic systems. To do this, we needed to know about the earthquake ground shaking and fault rupture. So we first constructed an earthquake, taking all available earthquake research information, from trenching and exposed evidence of prehistoric earthquakes, to analysis of instrumental recordings of large earthquakes and the latest theory in earthquake source physics. We modeled a magnitude (M) 7.8 earthquake on the southern San Andreas Fault, a plausible event on the fault most likely to produce a major earthquake. This information was then fed forward into the rest of the ShakeOut Scenario. The damage impacts of the scenario earthquake were estimated using both HAZUS-MH and expert opinion through 13 special studies and 6 expert panels, and fall into four

  15. Superclustering in the explosion scenario

    NASA Technical Reports Server (NTRS)

    Weinberg, David H.; Ostriker, Jeremiah P.; Dekel, Avishai

    1989-01-01

    A simple toy model is used to study the spatial distribution of rich clusters in a generic type of explosion scenario. The model, parameterized by the distribution of shell radii and the filling factor, places spherical shells at random and identifies each 'knot' as a cluster. The resulting cluster correlation function is close to a power law extending to the diameter of the largest spheres. Richer clusters form at the intersections of bigger shells and so have stronger correlations. Typical shell radii and filling factors are required to produce the observed number density of clusters. Models with a power-law radius distribution also reproduce the richness distribution of clusters in the Abell catalog. Supercluster multiplicity functions, void probabilities, number counts, topology statistics, and velocity correlations confirm the presence of strong superclustering and quantify the non-Gaussian nature of the model.

  16. Superclustering in the explosion scenario

    NASA Technical Reports Server (NTRS)

    Weinberg, David H.; Ostriker, Jeremiah P.; Dekel, Avishai

    1989-01-01

    A simple toy model is used to study the spatial distribution of rich clusters in a generic type of explosion scenario. The model, parameterized by the distribution of shell radii and the filling factor, places spherical shells at random and identifies each 'knot' as a cluster. The resulting cluster correlation function is close to a power law extending to the diameter of the largest spheres. Richer clusters form at the intersections of bigger shells and so have stronger correlations. Typical shell radii and filling factors are required to produce the observed number density of clusters. Models with a power-law radius distribution also reproduce the richness distribution of clusters in the Abell catalog. Supercluster multiplicity functions, void probabilities, number counts, topology statistics, and velocity correlations confirm the presence of strong superclustering and quantify the non-Gaussian nature of the model.

  17. Radiation Detection Computational Benchmark Scenarios

    SciTech Connect

    Shaver, Mark W.; Casella, Andrew M.; Wittman, Richard S.; McDonald, Ben S.

    2013-09-24

    Modeling forms an important component of radiation detection development, allowing for testing of new detector designs, evaluation of existing equipment against a wide variety of potential threat sources, and assessing operation performance of radiation detection systems. This can, however, result in large and complex scenarios which are time consuming to model. A variety of approaches to radiation transport modeling exist with complementary strengths and weaknesses for different problems. This variety of approaches, and the development of promising new tools (such as ORNL’s ADVANTG) which combine benefits of multiple approaches, illustrates the need for a means of evaluating or comparing different techniques for radiation detection problems. This report presents a set of 9 benchmark problems for comparing different types of radiation transport calculations, identifying appropriate tools for classes of problems, and testing and guiding the development of new methods. The benchmarks were drawn primarily from existing or previous calculations with a preference for scenarios which include experimental data, or otherwise have results with a high level of confidence, are non-sensitive, and represent problem sets of interest to NA-22. From a technical perspective, the benchmarks were chosen to span a range of difficulty and to include gamma transport, neutron transport, or both and represent different important physical processes and a range of sensitivity to angular or energy fidelity. Following benchmark identification, existing information about geometry, measurements, and previous calculations were assembled. Monte Carlo results (MCNP decks) were reviewed or created and re-run in order to attain accurate computational times and to verify agreement with experimental data, when present. Benchmark information was then conveyed to ORNL in order to guide testing and development of hybrid calculations. The results of those ADVANTG calculations were then sent to PNNL for

  18. Toward XML Representation of NSS Simulation Scenario for Mission Scenario Exchange Capability

    DTIC Science & Technology

    2003-09-01

    Combat XXI Program...........................13 2. Transition NSS to a Java Environment ...........................................13 3. Shift to an...and Reconnaissance IV&V Independent Verification and Validation xvi JCS Joint Chiefs of Staff JDOM Java Document Object Model...Scenario .xml NSS Simulation Scenario .xsd NSS Simulation Scenario . java NSS Simulation Scenario Text ? XML .xslt NSS Simulation

  19. Characteristics and Scenarios Projection of Climate Change on the Tibetan Plateau

    PubMed Central

    Hao, Zhenchun; Ju, Qin; Jiang, Weijuan; Zhu, Changjun

    2013-01-01

    The Fourth Assessment Report of the Intergovernmental Panel on Climate Change (IPCC AR4) presents twenty-two global climate models (GCMs). In this paper, we evaluate the ability of 22 GCMs to reproduce temperature and precipitation over the Tibetan Plateau by comparing with ground observations for 1961~1900. The results suggest that all the GCMs underestimate surface air temperature and most models overestimate precipitation in most regions on the Tibetan Plateau. Only a few models (each 5 models for precipitation and temperature) appear roughly consistent with the observations in annual temperature and precipitation variations. Comparatively, GFCM21 and CGMR are able to better reproduce the observed annual temperature and precipitation variability over the Tibetan Plateau. Although the scenarios predicted by the GCMs vary greatly, all the models predict consistently increasing trends in temperature and precipitation in most regions in the Tibetan Plateau in the next 90 years. The results suggest that the temperature and precipitation will both increase in all three periods under different scenarios, with scenario A1 increasing the most and scenario A1B increasing the least. PMID:23970827

  20. Web Based Tool for Mission Operations Scenarios

    NASA Technical Reports Server (NTRS)

    Boyles, Carole A.; Bindschadler, Duane L.

    2008-01-01

    A conventional practice for spaceflight projects is to document scenarios in a monolithic Operations Concept document. Such documents can be hundreds of pages long and may require laborious updates. Software development practice utilizes scenarios in the form of smaller, individual use cases, which are often structured and managed using UML. We have developed a process and a web-based scenario tool that utilizes a similar philosophy of smaller, more compact scenarios (but avoids the formality of UML). The need for a scenario process and tool became apparent during the authors' work on a large astrophysics mission. It was noted that every phase of the Mission (e.g., formulation, design, verification and validation, and operations) looked back to scenarios to assess completeness of requirements and design. It was also noted that terminology needed to be clarified and structured to assure communication across all levels of the project. Attempts to manage, communicate, and evolve scenarios at all levels of a project using conventional tools (e.g., Excel) and methods (Scenario Working Group meetings) were not effective given limitations on budget and staffing. The objective of this paper is to document the scenario process and tool created to offer projects a low-cost capability to create, communicate, manage, and evolve scenarios throughout project development. The process and tool have the further benefit of allowing the association of requirements with particular scenarios, establishing and viewing relationships between higher- and lower-level scenarios, and the ability to place all scenarios in a shared context. The resulting structured set of scenarios is widely visible (using a web browser), easily updated, and can be searched according to various criteria including the level (e.g., Project, System, and Team) and Mission Phase. Scenarios are maintained in a web-accessible environment that provides a structured set of scenario fields and allows for maximum

  1. Web Based Tool for Mission Operations Scenarios

    NASA Technical Reports Server (NTRS)

    Boyles, Carole A.; Bindschadler, Duane L.

    2008-01-01

    A conventional practice for spaceflight projects is to document scenarios in a monolithic Operations Concept document. Such documents can be hundreds of pages long and may require laborious updates. Software development practice utilizes scenarios in the form of smaller, individual use cases, which are often structured and managed using UML. We have developed a process and a web-based scenario tool that utilizes a similar philosophy of smaller, more compact scenarios (but avoids the formality of UML). The need for a scenario process and tool became apparent during the authors' work on a large astrophysics mission. It was noted that every phase of the Mission (e.g., formulation, design, verification and validation, and operations) looked back to scenarios to assess completeness of requirements and design. It was also noted that terminology needed to be clarified and structured to assure communication across all levels of the project. Attempts to manage, communicate, and evolve scenarios at all levels of a project using conventional tools (e.g., Excel) and methods (Scenario Working Group meetings) were not effective given limitations on budget and staffing. The objective of this paper is to document the scenario process and tool created to offer projects a low-cost capability to create, communicate, manage, and evolve scenarios throughout project development. The process and tool have the further benefit of allowing the association of requirements with particular scenarios, establishing and viewing relationships between higher- and lower-level scenarios, and the ability to place all scenarios in a shared context. The resulting structured set of scenarios is widely visible (using a web browser), easily updated, and can be searched according to various criteria including the level (e.g., Project, System, and Team) and Mission Phase. Scenarios are maintained in a web-accessible environment that provides a structured set of scenario fields and allows for maximum

  2. Innovations in science and scenarios for assessment

    DOE PAGES

    Kunkel, Kenneth E.; Moss, Richard; Parris, Adam

    2015-08-29

    Scenarios for the Third National Climate Assessment (NCA3) were produced for physical climate and sea level rise with substantial input from disciplinary and regional experts. These scenarios underwent extensive review and were published as NOAA Technical Reports. For land use/cover and socioeconomic conditions, scenarios already developed by other agencies were specified for use in the NCA3. Efforts to enhance participatory scenario planning as an assessment activity were pursued, but with limited success. Issues and challenges included the timing of availability of scenarios, the need for guidance in use of scenarios, the need for approaches to nest information within multiple scalesmore » and sectors, engagement and collaboration of end users in scenario development, and development of integrated scenarios. Future assessments would benefit from an earlier start to scenarios development, the provision of training in addition to guidance documents, new and flexible approaches for nesting information, ongoing engagement and advice from both scientific and end user communities, and the development of consistent and integrated scenarios.« less

  3. Innovations in science and scenarios for assessment

    SciTech Connect

    Kunkel, Kenneth E.; Moss, Richard; Parris, Adam

    2015-08-29

    Scenarios for the Third National Climate Assessment (NCA3) were produced for physical climate and sea level rise with substantial input from disciplinary and regional experts. These scenarios underwent extensive review and were published as NOAA Technical Reports. For land use/cover and socioeconomic conditions, scenarios already developed by other agencies were specified for use in the NCA3. Efforts to enhance participatory scenario planning as an assessment activity were pursued, but with limited success. Issues and challenges included the timing of availability of scenarios, the need for guidance in use of scenarios, the need for approaches to nest information within multiple scales and sectors, engagement and collaboration of end users in scenario development, and development of integrated scenarios. Future assessments would benefit from an earlier start to scenarios development, the provision of training in addition to guidance documents, new and flexible approaches for nesting information, ongoing engagement and advice from both scientific and end user communities, and the development of consistent and integrated scenarios.

  4. Innovations in science and scenarios for assessment.

    PubMed

    Kunkel, Kenneth E; Moss, Richard; Parris, Adam

    Scenarios for the Third National Climate Assessment (NCA3) were produced for physical climate and sea level rise with substantial input from disciplinary and regional experts. These scenarios underwent extensive review and were published as NOAA Technical Reports. For land use/cover and socioeconomic conditions, scenarios already developed by other agencies were specified for use in the NCA3. Efforts to enhance participatory scenario planning as an assessment activity were pursued, but with limited success. Issues and challenges included the timing of availability of scenarios, the need for guidance in use of scenarios, the need for approaches to nest information within multiple scales and sectors, engagement and collaboration of end users in scenario development, and development of integrated scenarios. Future assessments would benefit from an earlier start to scenarios development, the provision of training in addition to guidance documents, new and flexible approaches for nesting information, ongoing engagement and advice from both scientific and end user communities, and the development of consistent and integrated scenarios.

  5. Innovations in science and scenarios for assessment

    SciTech Connect

    Kunkel, Kenneth E.; Moss, Richard; Parris, Adam

    2015-08-29

    Scenarios for the Third National Climate Assessment (NCA3) were produced for physical climate and sea level rise with substantial input from disciplinary and regional experts. These scenarios underwent extensive review and were published as NOAA Technical Reports. For land use/cover and socioeconomic conditions, scenarios already developed by other agencies were specified for use in the NCA3. Efforts to enhance participatory scenario planning as an assessment activity were pursued, but with limited success. Issues and challenges included the timing of availability of scenarios, the need for guidance in use of scenarios, the need for approaches to nest information within multiple scales and sectors, engagement and collaboration of end users in scenario development, and development of integrated scenarios. Future assessments would benefit from an earlier start to scenarios development, the provision of training in addition to guidance documents, new and flexible approaches for nesting information, ongoing engagement and advice from both scientific and end user communities, and the development of consistent and integrated scenarios.

  6. Multiscale analysis of rainfall over France in a climate scenario: Importance of seasonal variations

    NASA Astrophysics Data System (ADS)

    Royer, Jean-François; Chauvin, Fabrice; Lovejoy, Shaun; Schertzer, Daniel; Tchiguirinskaia, Ioulia

    2010-05-01

    As a preliminary attempt to apply multifractal techniques to climate model simulations, Royer et al (2008) have analyzed the temporal scaling of daily rainfall time series over France simulated by the CNRM-CM3 coupled climate model in an IPCC scenario (SRES) A2 over the period 1860-2100. The scaling variability of the simulated daily rainfall, quantified with the "universal multifractal" formalism by means of a few relevant multifractal exponents characterizing the intermittency and multifractality of the field as determined by the Double Trace Moment (DTM), have shown a scaling range extending from one day to more than 16 days. Though opposite trends found in the evolution of the intermittency and multifractality exponents tend to have compensating effects on the evolution of rainfall extremes, the dominant effect of the increasing intermittency leads to expect an effective enhancement of rainfall extremes for the next hundred years. In this presentation, the analysis is extended by taking into consideration the seasonal effects. Comparison of the different periods shows that in winter there is rather little change in the two parameters, except in the southern part of France. In summer however, though the geographical patterns remain rather stable, a large and systematic evolution can be seen between the successive time spans, with an increase of multifractality and a decrease of intermittency over the 21st century. This new analysis shows that the overall trends found previously in analyzing the precipitation series over the whole year are mainly produced by the variations during the summer season. The very differentiated seasonal evolution in the response of precipitation to climate change, highligh that it is necessary to take into account a seasonal evolution of the multifractal parameters for characterizing the scaling properties of the rainfall fields. In particular the changes in the scaling properties of precipitation seem to be more prominent during

  7. Preliminary forecasts of Pacific bigeye tuna population trends under the A2 IPCC scenario

    NASA Astrophysics Data System (ADS)

    Lehodey, P.; Senina, I.; Sibert, J.; Bopp, L.; Calmettes, B.; Hampton, J.; Murtugudde, R.

    2010-07-01

    An improved version of the spatial ecosystem and population dynamics model SEAPODYM was used to investigate the potential impacts of global warming on tuna populations. The model included an enhanced definition of habitat indices, movements, and accessibility of tuna predators to different vertically migrant and non-migrant micronekton functional groups. The simulations covered the Pacific basin (model domain) at a 2° × 2° geographic resolution. The structure of the model allows an evaluation from multiple data sources, and parameterization can be optimized by adjoint techniques and maximum likelihood using fishing data. A first such optimized parameterization was obtained for bigeye tuna ( Thunnus obesus) in the Pacific Ocean using historical catch data for the last 50 years and a hindcast from a coupled physical-biogeochemical model driven by the NCEP atmospheric reanalysis. The parameterization provided very plausible biological parameter values and a good fit to fishing data from the different fisheries, both within and outside the time period used for optimization. We then employed this model to forecast the future of bigeye tuna populations in the Pacific Ocean. The simulation was driven by the physical-biogeochemical fields predicted from a global marine biogeochemistry - climate simulation. This global simulation was performed with the IPSL climate model version 4 (IPSL-CM4) coupled to the oceanic biogeochemical model PISCES and forced by atmospheric CO 2, from historical records over 1860-2000, and under the SRES A2 IPCC scenario for the 21st century (i.e. atmospheric CO 2 concentration reaching 850 ppm in the year 2100). Potential future changes in distribution and abundance under the IPCC scenario are presented but without taking into account any fishing effort. The simulation showed an improvement in bigeye tuna spawning habitat both in subtropical latitudes and in the eastern tropical Pacific (ETP) where the surface temperature becomes optimal for

  8. The narcissistic scenarios of parenthood.

    PubMed

    Manzano, J; Palacio Espasa, F; Zilkha, N

    1999-06-01

    The authors begin by pointing out that Freud always considered parent-child relations in terms of the child's psychic development and took little account of the parents' experience of the relationship and its psychic effects on them. They recall Freud's distinction between the anaclitic and narcissistic modes of relationship and show how these are unconsciously embodied and enacted in varying proportions in the cases observed in their own clinical practice of therapeutic consultations with parents and young children. After a review of the relevant psychoanalytic literature, the authors present their concept of the narcissistic scenarios of parenthood, which include parental projection on to the child, parental counter-identification, a specific aim and a relational dynamic that is acted out. Depending on the individual situation, the effects may help to structure the developing psyche or, if the narcissistic element is excessive, they may be pathological. The authors consider the literature on the application of psychoanalysis to therapeutic interventions with parents and children, stressing the technical importance of establishing a therapeutic focus. These ideas are illustrated by a detailed case history showing the interaction between a mother and a 4-year-old girl and how it was modified by a short therapy. The differences between interpretation in this situation and in the classical psychoanalytic setting are explained, and the paper ends with some comments on the transmission of psychic elements from generation to generation.

  9. Agricultural Baseline (BL0) scenario

    DOE Data Explorer

    Davis, Maggie R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)] (ORCID:0000000181319328); Hellwinckel, Chad M [University of Tennessee] (ORCID:0000000173085058); Eaton, Laurence [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)] (ORCID:0000000312709626); Turhollow, Anthony [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)] (ORCID:0000000228159350); Brandt, Craig [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)] (ORCID:0000000214707379); Langholtz, Matthew H. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)] (ORCID:0000000281537154)

    2016-07-13

    Scientific reason for data generation: to serve as the reference case for the BT16 volume 1 agricultural scenarios. The agricultural baseline runs from 2015 through 2040; a starting year of 2014 is used. Date the data set was last modified: 02/12/2016 How each parameter was produced (methods), format, and relationship to other data in the data set: simulation was developed without offering a farmgate price to energy crops or residues (i.e., building on both the USDA 2015 baseline and the agricultural census data (USDA NASS 2014). Data generated are .txt output files by year, simulation identifier, county code (1-3109). Instruments used: POLYSYS (version POLYS2015_V10_alt_JAN22B) supplied by the University of Tennessee APAC The quality assurance and quality control that have been applied: • Check for negative planted area, harvested area, production, yield and cost values. • Check if harvested area exceeds planted area for annuals. • Check FIPS codes.

  10. Climate change scenarios and key climate indices in the Swiss Alpine region

    NASA Astrophysics Data System (ADS)

    Zubler, Elias; Croci-Maspoli, Mischa; Frei, Christoph; Liniger, Mark; Scherrer, Simon; Appenzeller, Christof

    2013-04-01

    For climate adaption and to support climate mitigation policy it is of outermost importance to demonstrate the consequences of climate change on a local level and in user oriented quantities. Here, a framework is presented to apply the Swiss national climate change scenarios CH2011 to climate indices with direct relevance to applications, such as tourism, transportation, agriculture and health. This framework provides results on a high spatial and temporal resolution and can also be applied in mountainous regions such as the Alps. Results are shown for some key indices, such as the number of summer days and tropical nights, growing season length, number of frost days, heating and cooling degree days, and the number of days with fresh snow. Particular focus is given to changes in the vertical distribution for the future periods 2020-2049, 2045-2074 and 2070-2099 relative to the reference period 1980-2009 for the A1B, A2 and RCP3PD scenario. The number of days with fresh snow is approximated using a combination of temperature and precipitation as proxies. Some findings for the latest scenario period are: (1) a doubling of the number of summer days by the end of the century under the business-as-usual scenario A2, (2) tropical nights appear above 1500 m asl, (3) the number of frost days may be reduced by more than 3 months at altitudes higher than 2500 m, (4) an overall reduction of heating degree days of about 30% by the end of the century, but on the other hand an increase in cooling degree days in warm seasons, and (5) the number of days with fresh snow tends to go towards zero at low altitudes. In winter, there is little change in snowfall above 2000 m asl (roughly -3 days) in all scenarios. The largest impact on snowfall is found along the Northern Alpine flank and the Jura (-10 days or roughly -50% in A1B for the winter season). It is also highlighted that the future projections for all indices strongly depend on the chosen scenario and on model uncertainty

  11. Effects of future climate and land use scenarios on riverine source water quality.

    PubMed

    Delpla, Ianis; Rodriguez, Manuel J

    2014-09-15

    Surface water quality is particularly sensitive to land use practices and climatic events that affect its catchment. The relative influence of a set of watershed characteristics (climate, land use, morphology and pedology) and climatic variables on two key water quality parameters (turbidity and fecal coliforms (FC)) was examined in 24 eastern Canadian catchments at various spatial scales (1 km, 5 km, 10 km and the entire catchment). A regression analysis revealed that the entire catchment was a better predictor of water quality. Based on this information, linear mixed effect models for predicting turbidity and FC levels were developed. A set of land use and climate scenarios was considered and applied within the water quality models. Four land use scenarios (no change, same rate of variation, optimistic and pessimistic) and three climate change scenarios (B1, A1B and A2) were tested and variations for the near future (2025) were assessed and compared to the reference period (2000). Climate change impacts on water quality remained low annually for this time horizon (turbidity: +1.5%, FC: +1.6%, A2 scenario). On the other hand, the influence of land use changes appeared to predominate. Significant benefits for both parameters could be expected following the optimistic scenario (turbidity: -16.4%, FC: -6.3%; p < 0.05). However, pessimistic land use scenario led to significant increases on an annual basis (turbidity: +11.6%, FC: +15.2%; p < 0.05). Additional simulations conducted for the late 21st century (2090) revealed that climate change impacts could become equivalent to those modeled for land use for this horizon. Copyright © 2014 Elsevier B.V. All rights reserved.

  12. Nowhere to Invade: Rumex crispus and Typha latifolia Projected to Disappear under Future Climate Scenarios

    PubMed Central

    Xu, Zhonglin; Feng, Zhaodong; Yang, Jianjun; Zheng, Jianghua; Zhang, Fang

    2013-01-01

    Future climate change has been predicted to affect the potential distribution of plant species. However, only few studies have addressed how invasive species may respond to future climate change despite the known effects of plant species invasion on nutrient cycles, ecosystem functions, and agricultural yields. In this study, we predicted the potential distributions of two invasive species, Rumex crispus and Typha latifolia, under current and future (2050) climatic conditions. Future climate scenarios considered in our study include A1B, A2, A2A, B1, and B2A. We found that these two species will lose their habitat under the A1B, A2, A2A, and B1 scenarios. Their distributions will be maintained under future climatic conditions related to B2A scenarios, but the total area will be less than 10% of that under the current climatic condition. We also investigated variations of the most influential climatic variables that are likely to cause habitat loss of the two species. Our results demonstrate that rising mean annual temperature, variations of the coldest quarter, and precipitation of the coldest quarter are the main factors contributing to habitat loss of R. crispus. For T. latifolia, the main factors are rising mean annual temperature, variations in temperature of the coldest quarter, mean annual precipitation, and precipitation of the coldest quarter. These results demonstrate that the warmer and wetter climatic conditions of the coldest season (or month) will be mainly responsible for habitat loss of R. crispus and T. latifolia in the future. We also discuss uncertainties related to our study (and similar studies) and suggest that particular attention should be directed toward the manner in which invasive species cope with rapid climate changes because evolutionary change can be rapid for species that invade new areas. PMID:23923020

  13. Nowhere to invade: Rumex crispus and Typha latifolia projected to disappear under future climate scenarios.

    PubMed

    Xu, Zhonglin; Feng, Zhaodong; Yang, Jianjun; Zheng, Jianghua; Zhang, Fang

    2013-01-01

    Future climate change has been predicted to affect the potential distribution of plant species. However, only few studies have addressed how invasive species may respond to future climate change despite the known effects of plant species invasion on nutrient cycles, ecosystem functions, and agricultural yields. In this study, we predicted the potential distributions of two invasive species, Rumex crispus and Typha latifolia, under current and future (2050) climatic conditions. Future climate scenarios considered in our study include A1B, A2, A2A, B1, and B2A. We found that these two species will lose their habitat under the A1B, A2, A2A, and B1 scenarios. Their distributions will be maintained under future climatic conditions related to B2A scenarios, but the total area will be less than 10% of that under the current climatic condition. We also investigated variations of the most influential climatic variables that are likely to cause habitat loss of the two species. Our results demonstrate that rising mean annual temperature, variations of the coldest quarter, and precipitation of the coldest quarter are the main factors contributing to habitat loss of R. crispus. For T. latifolia, the main factors are rising mean annual temperature, variations in temperature of the coldest quarter, mean annual precipitation, and precipitation of the coldest quarter. These results demonstrate that the warmer and wetter climatic conditions of the coldest season (or month) will be mainly responsible for habitat loss of R. crispus and T. latifolia in the future. We also discuss uncertainties related to our study (and similar studies) and suggest that particular attention should be directed toward the manner in which invasive species cope with rapid climate changes because evolutionary change can be rapid for species that invade new areas.

  14. Transportation accident scenarios for commercial spent fuel

    SciTech Connect

    Wilmot, E L

    1981-02-01

    A spectrum of high severity, low probability, transportation accident scenarios involving commercial spent fuel is presented together with mechanisms, pathways and quantities of material that might be released from spent fuel to the environment. These scenarios are based on conclusions from a workshop, conducted in May 1980 to discuss transportation accident scenarios, in which a group of experts reviewed and critiqued available literature relating to spent fuel behavior and cask response in accidents.

  15. Renormalization-group improved inflationary scenarios

    NASA Astrophysics Data System (ADS)

    Pozdeeva, E. O.; Vernov, S. Yu.

    2017-03-01

    The possibility to construct an inflationary scenario for renormalization-group improved potentials corresponding to the Higgs sector of quantum field models is investigated. Taking into account quantum corrections to the renormalization-group potential which sums all leading logs of perturbation theory is essential for a successful realization of the inflationary scenario, with very reasonable parameters values. The scalar electrodynamics inflationary scenario thus obtained are seen to be in good agreement with the most recent observational data.

  16. MIOSAT Mission Scenario and Design

    NASA Astrophysics Data System (ADS)

    Agostara, C.; Dionisio, C.; Sgroi, G.; di Salvo, A.

    2008-08-01

    MIOSAT ("Mssione Ottica su microSATellite") is a low-cost technological / scientific microsatellite mission for Earth Observation, funded by Italian Space Agency (ASI) and managed by a Group Agreement between Rheinmetall Italia - B.U. Spazio - Contraves as leader and Carlo Gavazzi Space as satellite manufacturer. Several others Italians Companies, SME and Universities are involved in the development team with crucial roles. MIOSAT is a microsatellite weighting around 120 kg and placed in a 525 km altitude sun-synchronuos circular LEO orbit. The microsatellite embarks three innovative optical payloads: Sagnac multi spectral radiometer (IFAC-CNR), Mach Zehender spectrometer (IMM-CNR), high resolution pancromatic camera (Selex Galileo). In addition three technological experiments will be tested in-flight. The first one is an heat pipe based on Marangoni effect with high efficiency. The second is a high accuracy Sun Sensor using COTS components and the last is a GNSS SW receiver that utilizes a Leon2 processor. Finally a new generation of 28% efficiency solar cells will be adopted for the power generation. The platform is highly agile and can tilt along and cross flight direction. The pointing accuracy is in the order of 0,1° for each axe. The pointing determination during images acquisition is <0,02° for the axis normal to the boresight and 0,04° for the boresight. This paper deals with MIOSAT mission scenario and definition, highlighting trade-offs for mission implementation. MIOSAT mission design has been constrained from challenging requirements in terms of satellite mass, mission lifetime, instrument performance, that have implied the utilization of satellite agility capability to improve instruments performance in terms of S/N and resolution. The instruments provide complementary measurements that can be combined in effective ways to exploit new applications in the fields of atmosphere composition analysis, Earth emissions, antropic phenomena, etc. The Mission

  17. The unfolding: scenario planning in nursing.

    PubMed

    Woude, Diana Vander; Damgaard, Gloria; Hegge, Margaret J; Soholt, Deb; Bunkers, Sandra Schmidt

    2003-01-01

    An interdisciplinary consortium organized a group to explore the meaning and the future of nursing in South Dakota using scenario planning. This column provides a general description of the four scenarios that emerged, some observations about how they might evolve, comments on their implications, and first-person stories, as told by fictitious residents. The process of scenario planning is connected to nursing science by explicating how five lessons of scenario planning are linked with Parse's human becoming concepts of creative imagining, glimpsing the paradoxical, and affirming personal becoming.

  18. From Scenarios to Test Implementations Via Promela

    NASA Astrophysics Data System (ADS)

    Ulrich, Andreas; Alikacem, El-Hachemi; Hallal, Hesham H.; Boroday, Sergiy

    We report on a tool for generating executable concurrent tests from scenarios specified as message sequence charts. The proposed approach features three steps: 1) Deriving a MSC test implementation from a MSC scenario, 2) Mapping the test implementation into a Promela model, 3) Generating executable test scripts in Java. The generation of an intermediate Promela model allows for model-checking to inspect the test implementation for properties like soundness, fault detection power as well as for consistency checking between different test scenarios. Moreover decoupling the executable test scripts from the scenario specification makes it possible to use different backend code generators to support other scripting languages when needed.

  19. Mitochondrial Genomic Analysis of Late Onset Alzheimer’s Disease Reveals Protective Haplogroups H6A1A/H6A1B: The Cache County Study on Memory in Aging

    PubMed Central

    Ridge, Perry G.; Maxwell, Taylor J.; Corcoran, Christopher D.; Norton, Maria C.; Tschanz, JoAnn T.; O’Brien, Elizabeth; Kerber, Richard A.; Cawthon, Richard M.; Munger, Ronald G.; Kauwe, John S. K.

    2012-01-01

    Background Alzheimer’s disease (AD) is the most common cause of dementia and AD risk clusters within families. Part of the familial aggregation of AD is accounted for by excess maternal vs. paternal inheritance, a pattern consistent with mitochondrial inheritance. The role of specific mitochondrial DNA (mtDNA) variants and haplogroups in AD risk is uncertain. Methodology/Principal Findings We determined the complete mitochondrial genome sequence of 1007 participants in the Cache County Study on Memory in Aging, a population-based prospective cohort study of dementia in northern Utah. AD diagnoses were made with a multi-stage protocol that included clinical examination and review by a panel of clinical experts. We used TreeScanning, a statistically robust approach based on haplotype networks, to analyze the mtDNA sequence data. Participants with major mitochondrial haplotypes H6A1A and H6A1B showed a reduced risk of AD (p = 0.017, corrected for multiple comparisons). The protective haplotypes were defined by three variants: m.3915G>A, m.4727A>G, and m.9380G>A. These three variants characterize two different major haplogroups. Together m.4727A>G and m.9380G>A define H6A1, and it has been suggested m.3915G>A defines H6A. Additional variants differentiate H6A1A and H6A1B; however, none of these variants had a significant relationship with AD case-control status. Conclusions/Significance Our findings provide evidence of a reduced risk of AD for individuals with mtDNA haplotypes H6A1A and H6A1B. These findings are the results of the largest study to date with complete mtDNA genome sequence data, yet the functional significance of the associated haplotypes remains unknown and replication in others studies is necessary. PMID:23028804

  20. Utility of Oatp1a/1b-knockout and OATP1B1/3-humanized mice in the study of OATP-mediated pharmacokinetics and tissue distribution: case studies with pravastatin, atorvastatin, simvastatin, and carboxydichlorofluorescein.

    PubMed

    Higgins, J William; Bao, Jing Q; Ke, Alice B; Manro, Jason R; Fallon, John K; Smith, Philip C; Zamek-Gliszczynski, Maciej J

    2014-01-01

    Although organic anion transporting polypeptide (OATP)-mediated hepatic uptake is generally conserved between rodents and humans at a gross pharmacokinetic level, the presence of three major hepatic OATPs with broad overlap in substrate and inhibitor affinity, and absence of rodent-human orthologs preclude clinical translation of single-gene knockout/knockin findings. At present, changes in pharmacokinetics and tissue distribution of pravastatin, atorvastatin, simvastatin, and carboxydichlorofluorescein were studied in oatp1a/1b-knockout mice lacking the three major hepatic oatp isoforms, and in knockout mice with liver-specific knockin of human OATP1B1 or OATP1B3. Relative to wild-type controls, oatp1a/1b-knockout mice exhibited 1.6- to 19-fold increased intravenous and 2.1- to 115-fold increased oral drug exposure, due to 33%-75% decreased clearance, 14%-60% decreased volume of distribution, and ≤74-fold increased oral bioavailability, with the magnitude of change depending on the contribution of oatp1a/1b to pharmacokinetics. Hepatic drug distribution was 4.2- to 196-fold lower in oatp1a/1b-knockout mice; distributional attenuation was less notable in kidney, brain, cardiac, and skeletal muscle. Knockin of OATP1B1 or OATP1B3 partially restored control clearance, volume, and bioavailability values (24%-142% increase, ≤47% increase, and ≤77% decrease vs. knockout, respectively), such that knockin pharmacokinetic profiles were positioned between knockout and wild-type mice. Consistent with liver-specific humanization, only hepatic drug distribution was partially restored (1.3- to 6.5-fold increase vs. knockout). Exposure and liver distribution changes in OATP1B1-humanized versus knockout mice predicted the clinical impact of OATP1B1 on oral exposure and contribution to human hepatic uptake of statins within 1.7-fold, but only after correcting for human/humanized mouse liver relative protein expression factor (OATP1B1 = 2.2, OATP1B3 = 0.30).

  1. Uncertainty in Integrated Assessment Scenarios

    SciTech Connect

    Mort Webster

    2005-10-17

    trends from a model for uncertainty projections. The probability distributions of these critical model drivers, and the resulting uncertainty in projections from a range of models, can provide the basis of future emission scenario set designs.

  2. Combined impacts of climate and socio-economic scenarios on irrigation water availability for a dry Mediterranean reservoir

    NASA Astrophysics Data System (ADS)

    Nunes, João Pedro; Jacinto, Rita; Keizer, Jan Jacob

    2017-04-01

    The impacts of climate and associated socio-economic changes on water availability, including supply and demand, quality, and storage volume, were evaluated for the Vale do Gaio reservoir in southern Portugal, located in a dry Mediterranean climate and already under drought stress. The SWAT model was applied with 6 scenarios for 2071-2100, involving two storylines (A1B and B1) with individual changes in climate (-9% annual rainfall, increasing in winter by +28 to +30%), socio-economic conditions (an increase in irrigation demand by 11%, and a replacement of cereals and pastures by sunflower), and a combination of both. Most future scenarios resulted in lower water availability, due to lower supply by streamflow (-19 to -27%) combined with higher irrigation demand (+3 to +21%). This resulted in more years with constraints on irrigation supply (presently: 28%; scenarios: 37 to 43%), although they were partially mitigated by lower losses due to storage excess discharge. However, land-use changes also decreased water quality by increasing sediment loads (+86 to +109%) and associated Phosphorus loads (+28 to +48%). This was mostly due to a projected replacement of existing pastures by sunflower cultivation for biodiesel, which was the major source of increased erosion. The combination of lower volumes and higher sediment and P flows also increased P concentrations in the reservoir (+29 to +93%), increasing conditions for eutrophication. Impacts were more severe in scenario A1B than in B1, and in combined changes than in climate or socio-economic changes alone. Water availability was resilient to climate change, as impacts led only to a moderate aggravation of present-day conditions. Lower future water availability could be addressed by improved supply and demand management strategies and, in the most extreme scenario, by water transfers from regional water reserves; future water quality issues, however, could be addressed through land-use policies aiming at soil

  3. Combined impacts of climate and socio-economic scenarios on irrigation water availability for a dry Mediterranean reservoir.

    PubMed

    Nunes, João Pedro; Jacinto, Rita; Keizer, Jan Jacob

    2017-04-15

    The impacts of climate and associated socio-economic changes on water availability, including supply and demand, quality, and storage volume, were evaluated for the Vale do Gaio reservoir in southern Portugal, located in a dry Mediterranean climate and already under drought stress. The SWAT model was applied with 6 scenarios for 2071-2100, involving two storylines (A1B and B1) with individual changes in climate (-9% rainfall, increasing in winter by +28 to +30%), socio-economic conditions (an increase in irrigation demand by 11%, and a replacement of cereals and pastures by sunflower), and a combination of both. Most future scenarios resulted in lower water availability, due to lower supply (-19 to -27%) combined with higher irrigation demand (+3 to +21%). This resulted in more years with limited irrigation supplies (presently: 28%; scenarios: 37 to 43%), although limitations were mitigated by lower losses to excess discharge. Land-use changes also decreased quality by increasing P concentrations (+29 to +93%). Impacts were more severe in scenario A1B than in B1, and in combined changes than in climate or socio-economic changes only. Water availability was resilient to climate change, as impacts led only to a moderate aggravation of present-day conditions. Lower future water availability could be addressed by supply and demand management strategies and, in the most extreme scenario, by water transfers from regional water reserves; water quality issues could be addressed through land-use policies. Results also highlighted the importance of taking the characteristics of water supply systems into account when designing adaptation measures for future changes. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Scenarios and decisionmaking for complex environmental systems

    Treesearch

    Stephen R. Carpenter; Adena R. Rissman

    2012-01-01

    Scenarios are used for expanding the scope of imaginable outcomes considered by assessments, planning exercises, or research projects on social-ecological systems. We discuss a global case study, the Millennium Ecosystem Assessment, and a regional project for an urbanizing agricultural watershed. Qualitative and quantitative aspects of scenarios are complementary....

  5. Multimedia Scenario in a Primary School

    ERIC Educational Resources Information Center

    Nulden, Urban; Ward, Bodil

    2002-01-01

    Multimedia as an educational technology tool is used throughout the educational system. In this article we present a research project where multimedia scenario was used to initiate a discussion about Internet use among students and teachers at a primary school. Multimedia scenario is the use of large screen multimedia to initiate and facilitate…

  6. Scenario Planning at College of Marin.

    ERIC Educational Resources Information Center

    College of Marin, Kentfield, CA.

    This article reviews the scenario planning process implemented at the College of Marin (California). Scenario planning is a creative process in which a group of people who share a common fate develop stories about different ways their future might unfold, and use these stories to make decisions about what path to take. The Global Business Network…

  7. Molecular Diagnostic Analysis of Outbreak Scenarios

    ERIC Educational Resources Information Center

    Morsink, M. C.; Dekter, H. E.; Dirks-Mulder, A.; van Leeuwen, W. B.

    2012-01-01

    In the current laboratory assignment, technical aspects of the polymerase chain reaction (PCR) are integrated in the context of six different bacterial outbreak scenarios. The "Enterobacterial Repetitive Intergenic Consensus Sequence" (ERIC) PCR was used to analyze different outbreak scenarios. First, groups of 2-4 students determined optimal…

  8. Eight Scenarios for Work in the Future.

    ERIC Educational Resources Information Center

    Morf, Martin

    1983-01-01

    Changes in society and technology could bring a broad variety of possible futures, as these eight scenarios of the world of work show. The scenarios depict what we can expect if technology continues to progress and reduce the number of jobs available. Future work may be challenging and profitable. (NW)

  9. Architectures for Developing Multiuser, Immersive Learning Scenarios

    ERIC Educational Resources Information Center

    Nadolski, Rob J.; Hummel, Hans G. K.; Slootmaker, Aad; van der Vegt, Wim

    2012-01-01

    Multiuser immersive learning scenarios hold strong potential for lifelong learning as they can support the acquisition of higher order skills in an effective, efficient, and attractive way. Existing virtual worlds, game development platforms, and game engines only partly cater for the proliferation of such learning scenarios as they are often…

  10. Architectures for Developing Multiuser, Immersive Learning Scenarios

    ERIC Educational Resources Information Center

    Nadolski, Rob J.; Hummel, Hans G. K.; Slootmaker, Aad; van der Vegt, Wim

    2012-01-01

    Multiuser immersive learning scenarios hold strong potential for lifelong learning as they can support the acquisition of higher order skills in an effective, efficient, and attractive way. Existing virtual worlds, game development platforms, and game engines only partly cater for the proliferation of such learning scenarios as they are often…

  11. Molecular Diagnostic Analysis of Outbreak Scenarios

    ERIC Educational Resources Information Center

    Morsink, M. C.; Dekter, H. E.; Dirks-Mulder, A.; van Leeuwen, W. B.

    2012-01-01

    In the current laboratory assignment, technical aspects of the polymerase chain reaction (PCR) are integrated in the context of six different bacterial outbreak scenarios. The "Enterobacterial Repetitive Intergenic Consensus Sequence" (ERIC) PCR was used to analyze different outbreak scenarios. First, groups of 2-4 students determined optimal…

  12. Scenario Planning at College of Marin.

    ERIC Educational Resources Information Center

    College of Marin, Kentfield, CA.

    This article reviews the scenario planning process implemented at the College of Marin (California). Scenario planning is a creative process in which a group of people who share a common fate develop stories about different ways their future might unfold, and use these stories to make decisions about what path to take. The Global Business Network…

  13. Evaluation Framework for Dependable Mobile Learning Scenarios

    ERIC Educational Resources Information Center

    Bensassi, Manel; Laroussi, Mona

    2014-01-01

    The goal of the dependability analysis is to predict inconsistencies and to reveal ambiguities and incompleteness in the designed learning scenario. Evaluation, in traditional learning design, is generally planned after the execution of the scenario. In mobile learning, this stage becomes too difficult and expensive to apply due to the complexity…

  14. Regional Climate Change Scenarios for Mexico and Potential Impacts on Rainfed Maize Agriculture.

    NASA Astrophysics Data System (ADS)

    Conde, C.; Estrada, F.; Martínez, B.; Sánchez, O.; Monterroso, A.; Rosales, G.; Gay, C.

    2010-03-01

    Regional climate change scenarios that were used to assess the potential impacts on different sectors in Mexico are presented, with an application of those scenarios for the agricultural sector. The results of that research were delivered to the Mexican government for the development of the Mexican Fourth National Communication, which will be presented to the United Nations Framework Convention on Climate Change (UNFCCC). To generate regional climate change scenarios the models and criteria suggested by the Intergovernmental Panel on Climate Change (IPCC) in its Fourth Assessment Report (4AR) were applied. Those criteria are: Consistency with global projections, Physical plausibility, Applicability in impact assessments, Representative of the potential range of changes in the future, Accessibility for the users of impacts assessments. The regional scenarios that were generated focus mainly on the applicability and accessibility criteria. A kick-off meeting was held at the beginning of the research work for the Fourth National Communication, to ensure that those criteria were fulfilled. Specifically, a set of climate change scenarios was generated using the outputs for temperature and precipitation of three General Circulation Models (GCMs): ECHAM5, HADGEM1 y GFDL CM2.0, for the horizons 2030 and 2050, and for the emission scenarios A1B, A2, B2 y B1. Those scenarios can be found in our web page in a low spatial resolution (2.5 º x 2.5º), and with high resolution (5’ x 5’). To assess the potential impacts on rainfed maize agriculture, the changes of the suitability of different regions in the country were evaluated, considering maize temperature and precipitation requirements at its different stages of development. Four categories of suitability (high, moderated, marginal, and no suitable) were characterized for current and future climatic conditions. Using the A2 and B2 emission scenarios, the three GCMs and the horizon 2050, results showed that around 67% of

  15. Writing clinical scenarios for clinical science questions.

    PubMed

    Smith, Phil Em; Mucklow, John C

    2016-04-01

    Written knowledge assessments for physicians in training typically involve multiple-choice questions that use a clinical scenario in a single-best-answer format. The Royal College of Physicians Part 1 MRCP(UK) examination includes basic sciences themes that are challenging to assess through a clinical scenario. A realistic clinical setting based on everyday clinical practice and integral to the question is the clearest demonstration that the knowledge being assessed is clinically relevant. However, without special attention to detail, the scenario in a clinical science question can appear redundant or artificial. Reading unnecessary material frustrates candidates and threatens the reputation of the assessment. In this paper we discuss why a clinical scenario is important for basic science questions and offer advice on setting realistic and plausible clinical scenarios for such questions.

  16. Climate change scenarios for temperature and precipitation in Aragón (Spain).

    PubMed

    Ribalaygua, Jaime; Pino, M Rosa; Pórtoles, Javier; Roldán, Esther; Gaitán, Emma; Chinarro, David; Torres, Luis

    2013-10-01

    By applying a two-step statistical downscaling technique to four climate models under different future emission scenarios, we produced future projections of the daily precipitation and the maximum and minimum temperatures over the Spanish region of Aragón. The reliability of the downscaling technique was assessed by a verification process involving the comparison of the downscaled reanalysis data with the observed data--the results were very good for the temperature and acceptable for the precipitation. To determine the ability of the climate models to simulate the real climate, their simulations of the past (the 20C3M output) were downscaled and then compared with the observed climate. The results are quite robust for temperature and less conclusive for the precipitation. The downscaled future projections exhibit a significant increase during the entire 21st century of the maximum and minimum temperatures for all the considered IPCC future emission scenarios (A2, A1B, B1), both for mid-century (increases relative to the 1971-2000 averages between 1.5°C and 2.5°C, depending on the scenario) and for the end of the century (for the maximum temperature of approximately 3.75°C, 3.3°C, and 2.1°C for A2, A1B, and B1 scenarios respectively, and for the minimum temperature of 3.1°C, 2.75°C, and 1.75°C). The precipitation does not follow such a clear tendency (and exhibits greater uncertainties), but all the scenarios suggest a moderate decrease in rainfall for the mid-century (2-4%) and for the end of the century (4.5-5.5%). Due to the clear spatial differences in climate characteristics, we divided the studied area into five sub-regions to analyse the different changes on these areas; we determined that the high mountains (Pyrenees, Mediterranean-Oceanic transitional climate) and the lands of the Ebro River Basin (Continental sub-Mediterranean climate) will probably be the most affected. © 2013. Published by Elsevier B.V. All rights reserved.

  17. Scenario Development for Water Resources Planning and Management

    NASA Astrophysics Data System (ADS)

    Stewart, S.; Mahmoud, M.; Liu, Y.; Hartman, H.; Wagener, T.; Gupta, H.

    2006-12-01

    The main objective of scenario development for water resources is to inform policy-makers about the implications of various policies to inform decision-making. Although there have been a number of studies conducted in the relatively-new and recent field of scenario analysis and development, very few of those have been explicitly applied to water resource issues. More evident is the absence of an established formal approach to develop and apply scenarios. Scenario development is a process that evaluates possible future states of the world by examining several feasible scenarios. A scenario is a projection of various physical and socioeconomic conditions that describe change from the current state to a future state. In this paper, a general framework for scenario development with special emphasis on applications to water resources is considered. The process comprises several progressive and reiterative phases: scenario definition, scenario construction, scenario analysis, scenario assessment, and risk management. Several characteristics of scenarios that are important in describing scenarios are also taken into account; these include scenario types, scenario themes, scenario likelihoods and scenario categories. A hindrance to the adoption of a unified framework for scenario development is inconsistency in the terminology used by scenario developers. To address this problem, we propose a consistent terminology of basic and frequent terms. Outreach for this formal approach is partially maintained through an interactive community website that seeks to educate potential scenario developers about the scenario development process, share and exchange information and resources on scenarios to foster a multidisciplinary community of scenario developers, and establish a unified framework for scenario development with regards to terminology and guidelines. The website provides information on scenario development, current scenario-related activities, key water resources scenario

  18. ELPIS-JP: a dataset of local-scale daily climate change scenarios for Japan

    PubMed Central

    Iizumi, Toshichika; Semenov, Mikhail A.; Nishimori, Motoki; Ishigooka, Yasushi; Kuwagata, Tsuneo

    2012-01-01

    We developed a dataset of local-scale daily climate change scenarios for Japan (called ELPIS-JP) using the stochastic weather generators (WGs) LARS-WG and, in part, WXGEN. The ELPIS-JP dataset is based on the observed (or estimated) daily weather data for seven climatic variables (daily mean, maximum and minimum temperatures; precipitation; solar radiation; relative humidity; and wind speed) at 938 sites in Japan and climate projections from the multi-model ensemble of global climate models (GCMs) used in the coupled model intercomparison project (CMIP3) and multi-model ensemble of regional climate models form the Japanese downscaling project (called S-5-3). The capability of the WGs to reproduce the statistical features of the observed data for the period 1981–2000 is assessed using several statistical tests and quantile–quantile plots. Overall performance of the WGs was good. The ELPIS-JP dataset consists of two types of daily data: (i) the transient scenarios throughout the twenty-first century using projections from 10 CMIP3 GCMs under three emission scenarios (A1B, A2 and B1) and (ii) the time-slice scenarios for the period 2081–2100 using projections from three S-5-3 regional climate models. The ELPIS-JP dataset is designed to be used in conjunction with process-based impact models (e.g. crop models) for assessment, not only the impacts of mean climate change but also the impacts of changes in climate variability, wet/dry spells and extreme events, as well as the uncertainty of future impacts associated with climate models and emission scenarios. The ELPIS-JP offers an excellent platform for probabilistic assessment of climate change impacts and potential adaptation at a local scale in Japan. PMID:22291226

  19. Scripting Scenarios for the Human Patient Simulator

    NASA Technical Reports Server (NTRS)

    Bacal, Kira; Miller, Robert; Doerr, Harold

    2004-01-01

    The Human Patient Simulator (HPS) is particularly useful in providing scenario-based learning which can be tailored to fit specific scenarios and which can be modified in realtime to enhance the teaching environment. Scripting these scenarios so as to maximize learning requires certain skills, in order to ensure that a change in student performance, understanding, critical thinking, and/or communication skills results. Methods: A "good" scenario can be defined in terms of applicability, learning opportunities, student interest, and clearly associated metrics. Obstacles to such a scenario include a lack of understanding of the applicable environment by the scenario author(s), a desire (common among novices) to cover too many topics, failure to define learning objectives, mutually exclusive or confusing learning objectives, unskilled instructors, poor preparation , disorganized approach, or an inappropriate teaching philosophy (such as "trial by fire" or education through humiliation). Results: Descriptions of several successful teaching programs, used in the military, civilian, and NASA medical environments , will be provided, along with sample scenarios. Discussion: Simulator-based lessons have proven to be a time- and cost-efficient manner by which to educate medical personnel. Particularly when training for medical care in austere environments (pre-hospital, aeromedical transport, International Space Station, military operations), the HPS can enhance the learning experience.

  20. Combining regional climate and national human development scenarios to estimate future vulnerability to extreme climate and weather events

    NASA Astrophysics Data System (ADS)

    Patt, A.; Nussbaumer, P.

    2009-04-01

    , frequency of disasters in a country, urbanization, and the level of human development (capturing income, life expectancy, and education)—and the numbers of people killed or in need of assistance at the country level. We replicate results from past studies in showing that human development, perhaps surprisingly, shows a strong non-linear relationship with risk (with countries of intermediate levels of development showing the highest risk levels), although we extend these results through the controlling for other variables. Second, we downscale a suite of GCMs using national meteorological data, in order to generate ranges of estimates for changes in the frequency of each of the climate hazards. Supplementing this, we consider a climate scenario that sees a linear extrapolation of current trends in hazard frequency. Third, we construct scenarios for each of the socio-economic vulnerability drivers, consistent with IPCC SRES A2 and B1 scenarios for population and income changes, and UN estimates for other demographic changes. Pulling the three pieces of analysis together, we are able to construct risk scenarios until 2060. Our results are interesting in several respects. They show socio-economic development fully compensating for climate change in the impact on risk levels, within the range of estimated changes suggested by the suite of climate models. Recognizing the limits of models to predicting changed frequency of extreme events, there is also reason to believe that the current trend in increased hazard frequency may continue; for this latter scenario, risk levels rise substantially. Finally, given the observed non-linear relationship between development and risk, we observe in the B1 scenario risk levels at their highest level between 2030 and 2040, and then declining thereafter, as Mozambique passes the point of medium development. In the A2 scenario, by contrast, risk levels rise through mid-century, as development proceeds more slowly.

  1. Common Criteria Based Security Scenario Verification

    NASA Astrophysics Data System (ADS)

    Ohnishi, Atsushi

    Software is required to comply with the laws and standards of software security. However, stakeholders with less concern regarding security can neither describe the behaviour of the system with regard to security nor validate the system’s behaviour when the security function conflicts with usability. Scenarios or use-case specifications are common in requirements elicitation and are useful to analyze the usability of the system from a behavioural point of view. In this paper, the authors propose both (1) a scenario language based on a simple case grammar and (2) a method to verify a scenario with rules based on security evaluation criteria.

  2. Vocational training: the case scenario workshop.

    PubMed

    Winter-Moore, P H

    2001-01-01

    This article describes the procedure for conducting a workshop for a vocational training group, using six clinical case scenarios harvested from the vocational training group's own experience. During the session, the main group (which includes trainers) breaks up into smaller groups to discuss the management of each case, then a spokesperson presents the management solutions back to the re-assembled larger group: further interaction and discussion then takes place. This article discusses six typical case scenarios from a recent workshop. The case scenario workshop is an exciting way to encourage discussion and interaction with all parties involved.

  3. Interactive specification acquisition via scenarios: A proposal

    NASA Technical Reports Server (NTRS)

    Hall, Robert J.

    1992-01-01

    Some reactive systems are most naturally specified by giving large collections of behavior scenarios. These collections not only specify the behavior of the system, but also provide good test suites for validating the implemented system. Due to the complexity of the systems and the number of scenarios, however, it appears that automated assistance is necessary to make this software development process workable. Interactive Specification Acquisition Tool (ISAT) is a proposed interactive system for supporting the acquisition and maintenance of a formal system specification from scenarios, as well as automatic synthesis of control code and automated test generation. This paper discusses the background, motivation, proposed functions, and implementation status of ISAT.

  4. Connecting measurement invasiveness to optimal metrological scenarios

    NASA Astrophysics Data System (ADS)

    Moreira, Saulo V.; Adesso, Gerardo; Correa, Luis A.; Coudreau, Thomas; Keller, Arne; Milman, Pérola

    2017-07-01

    The connection between the Leggett-Garg inequality and optimal scenarios from the point of view of quantum metrology is investigated for perfect and noisy general dichotomic measurements. In this context, we show that the Fisher information can be expressed in terms of quantum temporal correlations. This connection allows us to associate scenarios with relatively high Fisher information to scenarios in which the Leggett-Garg inequality is violated. We thus demonstrate a qualitative and, to some extent, quantitative link between measurement invasiveness and metrological performance. Finally, we illustrate our results by using a specific model for spin systems.

  5. Mediterranean Sea response to climate change in an ensemble of twenty first century scenarios

    NASA Astrophysics Data System (ADS)

    Adloff, Fanny; Somot, Samuel; Sevault, Florence; Jordà, Gabriel; Aznar, Roland; Déqué, Michel; Herrmann, Marine; Marcos, Marta; Dubois, Clotilde; Padorno, Elena; Alvarez-Fanjul, Enrique; Gomis, Damià

    2015-11-01

    The Mediterranean climate is expected to become warmer and drier during the twenty-first century. Mediterranean Sea response to climate change could be modulated by the choice of the socio-economic scenario as well as the choice of the boundary conditions mainly the Atlantic hydrography, the river runoff and the atmospheric fluxes. To assess and quantify the sensitivity of the Mediterranean Sea to the twenty-first century climate change, a set of numerical experiments was carried out with the regional ocean model NEMOMED8 set up for the Mediterranean Sea. The model is forced by air-sea fluxes derived from the regional climate model ARPEGE-Climate at a 50-km horizontal resolution. Historical simulations representing the climate of the period 1961-2000 were run to obtain a reference state. From this baseline, various sensitivity experiments were performed for the period 2001-2099, following different socio-economic scenarios based on the Special Report on Emissions Scenarios. For the A2 scenario, the main three boundary forcings (river runoff, near-Atlantic water hydrography and air-sea fluxes) were changed one by one to better identify the role of each forcing in the way the ocean responds to climate change. In two additional simulations (A1B, B1), the scenario is changed, allowing to quantify the socio-economic uncertainty. Our 6-member scenario simulations display a warming and saltening of the Mediterranean. For the 2070-2099 period compared to 1961-1990, the sea surface temperature anomalies range from +1.73 to +2.97 °C and the SSS anomalies spread from +0.48 to +0.89. In most of the cases, we found that the future Mediterranean thermohaline circulation (MTHC) tends to reach a situation similar to the eastern Mediterranean Transient. However, this response is varying depending on the chosen boundary conditions and socio-economic scenarios. Our numerical experiments suggest that the choice of the near-Atlantic surface water evolution, which is very uncertain in

  6. Group 1: Scenario design and development issues

    NASA Technical Reports Server (NTRS)

    Sherwin, P.

    1981-01-01

    All LOFT scenarios and flight segments should be designed on the basis of a detailed statement of specific objectives. These objectives must state what kind of situation is to be addressed and why. The origin, routing, and destination of a particular scenario should be dictated by the specific objectives for that scenario or leg. Other factors to be considered are the desired weather, climate, etc. Simulator visual system, as well as other capabilities and limitations must be considered at a very early stage of scenario design. The simulator navigation area must be apropriate and must coincide with current Jeppeson charts. Much of the realism of LOFT is destroyed if the crew is unable to use current manuals and other materials.

  7. Nespoli and Kaleri during emergency scenario drill

    NASA Image and Video Library

    2011-01-11

    ISS026-E-016965 (11 Jan. 2011) --- Russian cosmonaut Alexander Kaleri (foreground) and European Space Agency astronaut Paolo Nespoli, both Expedition 26 flight engineers, participate in an emergency scenarios drill in the Kibo laboratory of the International Space Station.

  8. Kondratyev and Skripochka during emergency scenario drill

    NASA Image and Video Library

    2011-01-11

    ISS026-E-016976 (11 Jan. 2011) --- Russian cosmonauts Dmitry Kondratyev (left) and Oleg Skripochka, both Expedition 26 flight engineers, look over a procedures manual during an emergency scenarios drill in the Harmony node of the International Space Station.

  9. Nespoli and Kaleri during emergency scenario drill

    NASA Image and Video Library

    2011-01-11

    ISS026-E-016970 (11 Jan. 2011) --- Russian cosmonaut Alexander Kaleri (right) and European Space Agency astronaut Paolo Nespoli, both Expedition 26 flight engineers, participate in an emergency scenarios drill in the Kibo laboratory of the International Space Station.

  10. Nespoli and Kaleri during emergency scenario drill

    NASA Image and Video Library

    2011-01-11

    ISS026-E-016963 (11 Jan. 2011) --- Russian cosmonaut Alexander Kaleri (foreground) and European Space Agency astronaut Paolo Nespoli, both Expedition 26 flight engineers, participate in an emergency scenarios drill in the Kibo laboratory of the International Space Station.

  11. Scenarios for the Evolution of Asteroid Belts

    NASA Image and Video Library

    2012-11-01

    This illustration shows three possible scenarios for the evolution of asteroid belts. At the top, a Jupiter-size planet migrates through the asteroid belt, scattering material and inhibiting the formation of life on planets.

  12. FUTURE SCENARIOS OF CHANGE IN WILDLIFE HABITAT

    EPA Science Inventory

    Studies in Pennsylvania, Iowa, California, and Oregon show varying losses of terrestrial wildlife habitat in scenarios based on different assumptions about future human land use patterns. Retrospective estimates of losses of habitat since Euro-American settlement in several stud...

  13. Development and Validation of Videotaped Scenarios

    PubMed Central

    Noel, Nora E.; Maisto, Stephen A.; Johnson, James D.; Jackson, Lee A.; Goings, Christopher D.; Hagman, Brett T.

    2013-01-01

    Researchers using scenarios often neglect to validate perceived content and salience of embedded stimuli specifically with intended participants, even when such meaning is integral to the study. For example, sex and aggression stimuli are heavily influenced by culture, so participants may not perceive what researchers intended in sexual aggression scenarios. Using four studies, the authors describe the method of scenario validation to produce two videos assessing alcohol-related sexual aggression. Both videos are identical except for the presence in one video of antiforce cues that are extremely salient to the young heterosexual men. Focus groups and questionnaires validate these men's perceptions that (a) the woman was sexually interested, (b) the sexual cues were salient, (c) the antiforce cues were salient (antiaggression video only), and (e) these antiforce cues inhibited acceptance of forced sex. Results show the value of carefully selecting and validating content when assessing socially volatile variables and provide a useful template for developing culturally valid scenarios. PMID:18252938

  14. Combination of Face Regions in Forensic Scenarios.

    PubMed

    Tome, Pedro; Fierrez, Julian; Vera-Rodriguez, Ruben; Ortega-Garcia, Javier

    2015-07-01

    This article presents an experimental analysis of the combination of different regions of the human face on various forensic scenarios to generate scientific knowledge useful for the forensic experts. Three scenarios of interest at different distances are considered comparing mugshot and CCTV face images using MORPH and SC face databases. One of the main findings is that inner facial regions combine better in mugshot and close CCTV scenarios and outer facial regions combine better in far CCTV scenarios. This means, that depending of the acquisition distance, the discriminative power of the facial regions change, having in some cases better performance than the full face. This effect can be exploited by considering the fusion of facial regions which results in a very significant improvement of the discriminative performance compared to just using the full face. © 2015 American Academy of Forensic Sciences.

  15. Visualizing Risks: Icons for Information Attack Scenarios

    DTIC Science & Technology

    2000-10-01

    Visualizing Risks : Icons for Information Attack Scenarios Hilary H. Hosmer Data Security, Inc. Bedford, MA 01730 Email: hosmer@datasecinc.com...and omissions, thus speeding up risk analysis, requirements gathering, safeguard selection, cryptographic protocol analysis, and INFOSEC training...

  16. Model Performance Evaluation and Scenario Analysis (MPESA)

    EPA Pesticide Factsheets

    Model Performance Evaluation and Scenario Analysis (MPESA) assesses the performance with which models predict time series data. The tool was developed Hydrological Simulation Program-Fortran (HSPF) and the Stormwater Management Model (SWMM)

  17. Workforce management strategies in a disaster scenario.

    SciTech Connect

    Kelic, Andjelka; Turk, Adam L.

    2008-08-01

    A model of the repair operations of the voice telecommunications network is used to study labor management strategies under a disaster scenario where the workforce is overwhelmed. The model incorporates overtime and fatigue functions and optimizes the deployment of the workforce based on the cost of the recovery and the time it takes to recover. The analysis shows that the current practices employed in workforce management in a disaster scenario are not optimal and more strategic deployment of that workforce is beneficial.

  18. Up-regulation of gonadotropin mRNA-expression at the onset of gametogenesis in the roach (Rutilus rutilus): evidence for an important role of brain-type aromatase (cyp19a1b) in the pituitary.

    PubMed

    Trubiroha, Achim; Kroupova, Hana; Wuertz, Sven; Kloas, Werner

    2012-09-15

    The present study characterized changes in key parameters of reproduction in adult roach (Rutilus rutilus) from Lake Grosser Mueggelsee (Berlin, Germany) during natural gametogenesis. Fish of both sexes were sampled in monthly intervals between April and August in order to cover the onset of gametogenesis. Investigated parameters included gonad histology, plasma levels of 17β-oestradiol (E2), testosterone (T), 11-ketotestosterone (11-KT), and 17,20β-dihydroxy-4-pregnen-3-one (17,20β-P) as well as the expression of gonadotropin subunits in the pituitary. Furthermore, the mRNA-expression of brain-type aromatase (cyp19a1b), androgen receptor (ar), and estrogen receptor isoforms was studied at the pituitary level. The onset of gametogenesis - as indicated by follicles with cortical alveoli in females and first spermatogonia B in males - was observed in July, accompanied by a significant up-regulation of follicle-stimulating hormone β (fshβ) mRNA in the pituitary in both sexes. On the other hand, luteinizing hormone β (lhβ) mRNA increased later on in August. In males, the increase of fshβ mRNA in July coincided with a rise in plasma 11-KT concentrations. In females, E2 in plasma increased later, not until August, shortly before true vitellogenesis (late cortical alveoli stage). Expression of sex steroid receptors in the pituitary revealed only minor seasonal fluctuations. Most pronounced, ar mRNA displayed the highest level pre-spawning in both sexes. Interestingly, cyp19a1b mRNA-expression in the pituitary increased in parallel with fshβ already before any changes in plasma E2 or T occurred. These data suggest an important role of pituitary FSH and aromatase at the onset of gametogenesis in the roach. Copyright © 2012 Elsevier Inc. All rights reserved.

  19. The 5-HT1A/1B-receptor agonist eltoprazine increases both catecholamine release in the prefrontal cortex and dopamine release in the nucleus accumbens and decreases motivation for reward and "waiting" impulsivity, but increases "stopping" impulsivity.

    PubMed

    Korte, S Mechiel; Prins, Jolanda; Van den Bergh, Filip S; Oosting, Ronald S; Dupree, Rudy; Korte-Bouws, Gerdien A H; Westphal, Koen G C; Olivier, Berend; Denys, Damiaan A; Garland, Alexis; Güntürkün, Onur

    2017-01-05

    The 5-HT1A/1B-receptor agonist eltoprazine has a behavioral drug signature that resembles that of a variety of psychostimulant drugs, despite the differences in receptor binding profile. These psychostimulants are effective in treating impulsivity disorders, most likely because they increase norepinephrine (NE) and dopamine (DA) levels in the prefrontal cortex. Both amphetamine and methylphenidate, however, also increase dopamine levels in the nucleus accumbens (NAc), which has a significant role in motivation, pleasure, and reward. How eltoprazine affects monoamine release in the medial prefrontal cortex (mPFC), the orbitofrontal cortex (OFC), and the NAc is unknown. It is also unknown whether eltoprazine affects different forms of impulsivity and brain reward mechanisms. Therefore, in the present study, we investigate the effects of eltoprazine in rats in the following sequence: 1) the activity of the monoaminergic systems using in vivo microdialysis, 2) motivation for reward measured using the intracranial self-stimulation (ICSS) procedure, and finally, 3) "waiting" impulsivity in the delay-aversion task, and the "stopping" impulsivity in the stop-signal task. The microdialysis studies clearly showed that eltoprazine increased DA and NE release in both the mPFC and OFC, but only increased DA concentration in the NAc. In contrast, eltoprazine decreased 5-HT release in the mPFC and NAc (undetectable in the OFC). Remarkably, eltoprazine decreased impulsive choice, but increased impulsive action. Furthermore, brain stimulation was less rewarding following eltoprazine treatment. These results further support the long-standing hypothesis that "waiting" and "stopping" impulsivity are regulated by distinct neural circuits, because 5-HT1A/1B-receptor activation decreases impulsive choice, but increases impulsive action. Copyright © 2016 Elsevier B.V. All rights reserved.

  20. Sharing the burden of climate change stabilization: An energysector perspective

    SciTech Connect

    Wagner, Fabian; Sathaye, Jayant

    2006-05-01

    In this paper we discuss long-term least cost CO2stabilization scenarios based on the SRES AIM A1B scenario in the contextof an international burden-sharing regime. Starting from a stabilizationtarget, regional emission caps are formulated dynamically on the basis ofpast emissions. With these regional caps, the cost-optimal supply fuelmix in the energy sector in the four SRES world regions is calculated,and lower bounds on the volume of traded carbon are estimated. Theallocation scheme provides incentives for early mitigation action. Weestimate additional regional costs incurred by the allocation scheme, andassess the sensitivity of results to changes in the concentrationceiling, discount rates, and start date for burden sharing.

  1. Subsistence Exposure Scenarios for Tribal Applications

    PubMed Central

    Harper, Barbara; Harding, Anna; Harris, Stuart; Berger, Patricia

    2014-01-01

    The article provides an overview of methods that can be used to develop exposure scenarios for unique tribal natural resource usage patterns. Exposure scenarios are used to evaluate the degree of environmental contact experienced by people with different patterns of lifestyle activities, such as residence, recreation, or work. in 1994, U.S. President Bill Clinton's Executive Order 12898 recognized that disproportionately high exposures could be incurred by people with traditional subsistence lifestyles because of their more intensive contact with natural resources. Since then, we have developed several tribal exposure scenarios that reflect tribal-specific traditional lifeways. These scenarios are not necessarily intended to capture contemporary resource patterns, but to describe how the resources were used before contamination or degradation, and will be used once again in fully traditional ways after cleanup and restoration. The direct exposure factors for inhalation and soil ingestion rates are the same in each tribal scenario, but the diets are unique to each tribe and its local ecology, natural foods, and traditional practices. Scenarios, in part or in whole, also have other applications, such as developing environmental standards, evaluating disproportionate exposures, developing sampling plans, planning for climate change, or evaluating service flows as part of natural resource damage assessments. PMID:25197207

  2. Subsistence Exposure Scenarios for Tribal Applications.

    PubMed

    Harper, Barbara; Harding, Anna; Harris, Stuart; Berger, Patricia

    2012-07-01

    The article provides an overview of methods that can be used to develop exposure scenarios for unique tribal natural resource usage patterns. Exposure scenarios are used to evaluate the degree of environmental contact experienced by people with different patterns of lifestyle activities, such as residence, recreation, or work. in 1994, U.S. President Bill Clinton's Executive Order 12898 recognized that disproportionately high exposures could be incurred by people with traditional subsistence lifestyles because of their more intensive contact with natural resources. Since then, we have developed several tribal exposure scenarios that reflect tribal-specific traditional lifeways. These scenarios are not necessarily intended to capture contemporary resource patterns, but to describe how the resources were used before contamination or degradation, and will be used once again in fully traditional ways after cleanup and restoration. The direct exposure factors for inhalation and soil ingestion rates are the same in each tribal scenario, but the diets are unique to each tribe and its local ecology, natural foods, and traditional practices. Scenarios, in part or in whole, also have other applications, such as developing environmental standards, evaluating disproportionate exposures, developing sampling plans, planning for climate change, or evaluating service flows as part of natural resource damage assessments.

  3. Open Scenario Study: IDA Open Scenario Repository User’s Manual

    DTIC Science & Technology

    2010-01-01

    Using the prototype repository, the user can access and download each scenario through a hyperlink. The database administrator (DBA) has the option to...handle user security, upload and download of scenarios, message boards, blogs, wikis, or a scenario rating system; all of these features have been...file [AccessRuntime.EXE] from the CD or download it from the Microsoft Download Center. 7 There are no other system requirements, given the small

  4. Model sustainability in DSS design and scenario formulation: what are the right scenarios?

    PubMed

    Schreider SYu; Mostovaia, A D

    2001-09-01

    A concept of the integrated approach in designing multidisciplinary decision support systems (DSS) based on agricultural scenarios for sustainable catchment management is discussed. A principle of holism underlying the integrated approach to DSS design is formulated. For a model to be viable and sustainable, it should be based on scenarios that are plausible and highly typical from the point of view of those 'doing' agriculture. Problems concerning principles of scenario formulation within the integrated approach are considered. A notion of 'prototype' scenarios based on 'joint venture' of modellers and stakeholders is proposed.

  5. EDITORIAL: Where next with global environmental scenarios? Where next with global environmental scenarios?

    NASA Astrophysics Data System (ADS)

    O'Neill, Brian; Pulver, Simone; Van Deveer, Stacy; Garb, Yaakov

    2008-12-01

    Scenarios have become a standard tool in the portfolio of techniques that scientists and policy-makers use to envision and plan for the future. Defined as plausible, challenging and relevant stories about how the future might unfold that integrate quantitative models with qualitative assessments of social and political trends, scenarios are a central component in assessment processes for a range of global issues, including climate change, biodiversity, agriculture, and energy. Yet, despite their prevalence, systematic analysis of scenarios is in its beginning stages. Fundamental questions remain about both the epistemology and scientific credibility of scenarios and their roles in policymaking and social change. Answers to these questions have the potential to determine the future of scenario analyses. Is scenario analysis moving in the direction of earth system governance informed by global scenarios generated through increasingly complex and comprehensive models integrating socio-economic and earth systems? Or will global environmental scenario analyses lose favour compared to more focused, policy-driven, regionally specific modelling? These questions come at an important time for the climate change issue, given that the scenario community, catalyzed by the Intergovernmental Panel on Climate Change (IPCC), is currently preparing to embark on a new round of scenario development processes aimed at coordinating research and assessment, and informing policy, over the next five to ten years. These and related questions about where next to go with global environmental scenarios animated a workshop held at Brown University (Note1) that brought together leading practitioners and scholars of global environmental change scenarios from research, policy-making, advocacy, and business settings. The workshop aimed to provide an overview of current practices/best practices in scenario production and scenario use across a range of global environmental change arenas. Participants

  6. Multi-decadal scenario simulation over Korea using a one-way double-nested regional climate model system. Part 2: future climate projection (2021 2050)

    NASA Astrophysics Data System (ADS)

    Im, Eun-Soon; Ahn, Joong-Bae; Kwon, Won-Tae; Giorgi, Filippo

    2008-02-01

    An analysis of simulated future surface climate change over the southern half of Korean Peninsula using a RegCM3-based high-resolution one-way double-nested system is presented. Changes in mean climate as well as the frequency and intensity of extreme climate events are discussed for the 30-year-period of 2021 2050 with respect to the reference period of 1971 2000 based on the IPCC SRES B2 emission scenario. Warming in the range of 1 4°C is found throughout the analysis region and in all seasons. The warming is maximum in the higher latitudes of the South Korean Peninsula and in the cold season. A large reduction in snow depth is projected in response to the increase of winter minimum temperature induced by the greenhouse warming. The change in precipitation shows a distinct seasonal variation and a substantial regional variability. In particular, we find a large increase of wintertime precipitation over Korea, especially in the upslope side of major mountain systems. Summer precipitation increases over the northern part of South Korea and decreases over the southern regions, indicating regional diversity. The precipitation change also shows marked intraseasonal variations throughout the monsoon season. The temperature change shows a positive trend throughout 2021 2050 while the precipitation change is characterized by pronounced interdecadal variations. The PDF of the daily temperature is shifted towards higher values and is somewhat narrower in the scenario run than the reference one. The number of frost days decreases markedly and the number of hot days increases. The regional distribution of heavy precipitation (over 80 mm/day) changes considerably, indicating changes in flood vulnerable regions. The climate change signal shows pronounced fine scale signal over Korea, indicating the need of high-resolution climate simulations

  7. Water use implications of biofuel scenarios

    NASA Astrophysics Data System (ADS)

    Teter, J.; Mishra, G. S.; Yeh, S.

    2012-12-01

    Existing studies rely upon attributional lifecycle analysis (LCA) approaches to estimate water intensity of biofuels in liters of irrigated/evapotranspiration water consumed for biofuel production. Such approaches can be misleading. From a policy perspective, a better approach is to compare differential water impacts among scenarios on a landscape scale. We address the shortcomings of existing studies by using consequential LCA, and incorporate direct and indirect land use (changes) of biofuel scenarios, marginal vs. average biofuel water use estimates, future climate, and geographic heterogeneity. We use the outputs of a partial equilibrium economic model, climate and soil data, and a process-based crop-soil-climate-water model to estimate differences in green water (GW - directly from precipitation to soil) and blue water (BW - supplied by irrigation) use among three scenarios: (1) business-as-usual (BAU), (2) Renewable Fuels Standard (RFS) mandates, and (3) a national Low Carbon Fuel Standard (LCFS) plus the RFS scenario. We use spatial statistical methods to interpolate key climatic variables using daily climate observations for the contiguous USA. Finally, we use FAO's crop model AquaCrop to estimate the domestic GW and BW impacts of biofuel policies from 2007-2035. We assess the differences among scenarios along the following metrics: (1) crop area expansion at the county level, including prime and marginal lands, (2) crop-specific and overall annual/seasonal water balances including (a) water inflows (irrigation & precipitation), (b) crop-atmosphere interactions: (evaporation & transpiration) and (d) soil-water flows (runoff & soil infiltration), in mm 3 /acre over the relevant time period. The functional unit of analysis is the BW and GW requirements of biofuels (mm3 per Btu biofuel) at the county level. Differential water use impacts among scenarios are a primarily a function of (1) land use conversion, in particular that of formerly uncropped land classes

  8. USGS Multi-Hazards Winter Storm Scenario

    NASA Astrophysics Data System (ADS)

    Cox, D. A.; Jones, L. M.; Perry, S. C.

    2008-12-01

    The USGS began an inter-disciplinary effort, the Multi Hazards Demonstration Project (MHDP), in 2007 to demonstrate how hazards science can improve a community's resiliency to natural disasters including earthquakes, tsunamis, wildfires, landslides, floods and coastal erosion. The project engages the user community in setting research goals and directs efforts towards research products that can be applied to loss reduction and improved resiliency. The first public product of the MHDP was the ShakeOut Earthquake Scenario published in May 2008. It detailed the realistic outcomes of a hypothetical, but plausible, magnitude 7.8 earthquake on the San Andreas Fault in southern California. Over 300 scientist and experts contributed to designing the earthquake and understanding the impacts of such a disaster, including the geotechnical, engineering, social, cultural, environmental, and economic consequences. The scenario advanced scientific understanding and exposed numerous vulnerabilities related to emergency response and lifeline continuity management. The ShakeOut Scenario was the centerpiece of the Nation's largest-ever emergency response exercise in November 2008, dubbed "The Great Southern California ShakeOut" (www.shakeout.org). USGS Multi-Hazards is now preparing for its next major public project, a Winter Storm Scenario. Like the earthquake scenario, experts will be brought together to examine in detail the possibility, cost and consequences of a winter storm disaster including floods, landslides, coastal erosion and inundation; debris flows; biologic consequences like extirpation of endangered species; physical damages like bridge scour, road closures, dam failure, property loss, and water system collapse. Consideration will be given to the vulnerabilities associated with a catastrophic disruption to the water supply to southern California; the resulting impacts on ground water pumping, seawater intrusion, water supply degradation, and land subsidence; and a

  9. Arctic shipping emissions inventories and future scenarios

    NASA Astrophysics Data System (ADS)

    Corbett, J. J.; Lack, D. A.; Winebrake, J. J.; Harder, S.; Silberman, J. A.; Gold, M.

    2010-10-01

    This paper presents 5 km×5 km Arctic emissions inventories of important greenhouse gases, black carbon and other pollutants under existing and future (2050) scenarios that account for growth of shipping in the region, potential diversion traffic through emerging routes, and possible emissions control measures. These high-resolution, geospatial emissions inventories for shipping can be used to evaluate Arctic climate sensitivity to black carbon (a short-lived climate forcing pollutant especially effective in accelerating the melting of ice and snow), aerosols, and gaseous emissions including carbon dioxide. We quantify ship emissions scenarios which are expected to increase as declining sea ice coverage due to climate change allows for increased shipping activity in the Arctic. A first-order calculation of global warming potential due to 2030 emissions in the high-growth scenario suggests that short-lived forcing of ~4.5 gigagrams of black carbon from Arctic shipping may increase global warming potential due to Arctic ships' CO2 emissions (~42 000 gigagrams) by some 17% to 78%. The paper also presents maximum feasible reduction scenarios for black carbon in particular. These emissions reduction scenarios will enable scientists and policymakers to evaluate the efficacy and benefits of technological controls for black carbon, and other pollutants from ships.

  10. Scenario development in China's electricity sector

    SciTech Connect

    Steenhof, P.A.; Fulton, W.

    2007-07-15

    The continuing growth of China's electricity sector will affect global environmental and economic sustainability due to its impacts on greenhouse gas emissions and global resource depletion. In 2005, the generation of electricity in China resulted in the emissions of 2290 million metric tonnes of carbon dioxide (approximately 53% of the nation's total) and required 779 million metric tonnes of coal (approximately 50% of China's total coal consumption). These figures are expected to increase with China's economic growth. In order to gauge the range in which fuel consumption and CO{sub 2} emissions could grow a scenario-based conceptual model has been developed by the authors (published in this journal). The application and analysis of this shows that under a business as usual (BAU) scenario, electricity generation could contribute upwards of 56% of China's energy related greenhouse gas emissions by 2020. Meanwhile, consumption of coal will also increase, growing to nearly 60% of total national demand by 2020. However, variations in a number of key drivers could produce significant deviation from the BAU scenario. With accelerated economic output, even with greater technological advances and greater potential to bring natural gas on stream, carbon dioxide emissions would rise 10% above the BAU. Alternatively, in a scenario where China's economy grows at a tempered pace, less investment would be available for advanced technologies, developing natural gas infrastructure, or nuclear energy. In this scenario, reduced economic growth and electricity demand would thereby be countered by reduced efficiency and a higher contribution of coal.

  11. Development of nonproliferation and assessment scenarios.

    SciTech Connect

    Finley, Melissa; Barnett, Natalie Beth

    2005-10-01

    The overall objective of the Nonproliferation and Assessments Scenario Development project is to create and analyze potential and plausible scenarios that would lead to an adversary's ability to acquire and use a biological weapon. The initial three months of funding was intended to be used to develop a scenario to demonstrate the efficacy of this analysis methodology; however, it was determined that a substantial amount of preliminary data collection would be needed before a proof of concept scenario could be developed. We have dedicated substantial effort to determine the acquisition pathways for Foot and Mouth Disease Virus, and similar processes will be applied to all pathogens of interest. We have developed a biosecurity assessments database to capture information on adversary skill locales, available skill sets in specific regions, pathogen sources and regulations involved in pathogen acquisition from legitimate facilities. FY06 funding, once released, will be dedicated to data collection on acquisition, production and dissemination requirements on a pathogen basis. Once pathogen data has been collected, scenarios will be developed and scored.

  12. Analysis of climate variability under various scenarios for future urban growth in Seoul Metropolitan Area (SMA), Korea

    NASA Astrophysics Data System (ADS)

    Kim, H.; Jeong, J.; Kim, Y.

    2011-12-01

    It is important to adjust urban growth data closer to reality in the regional climate model because urban changes give effects to physical properties such as albedo, moisture availability and roughness length in the atmosphere. Future urban growth, however, has not been considered widely in the prediction model for future climate change. In this study, we used the urban growth model called SLEUTH (Slope, Land-use, Excluded, Urban, Transportation, Hill-shade) based on cellular automata (CA) technique to predict the future urban growth. The target area is Seoul Metropolitan area (SMA) where the urban area explosively has expanded the most in the Korean peninsula due to the continuous industrialization since 1970s. The SLEUTH model was calibrated to know the pattern of the urban growth in SMA with historical data for 35 years (1975-2000) provided from Water Management Information System (WAMIS) in Korea and then the future urban growth was projected out to 2050 assuming three different scenarios: (1) current trends scenario (Scenario 1; SC1), (2) regional policy and urban planning scenario (Scenario 2; SC2), (3) ecologically protection scenario (Scenario 3; SC3). As a result, the urban ratios by scenarios were increased 12.87, 11.17 and 6.26 percentages of the total area for 50 years respectively. These predictions of SLEUTH model used as the boundary condition data and the 6 hourly data of ECHAM5/OM-1 A1B scenarios generated by Max-Plank Institute for Meteorology in Hamburg, Germany used as the initial condition data in Weather Research and Forecasting (WRF) model. We designed four different numerical experiments in accordance with the four scenarios for the urban growth (SC1, SC2, SC3 and Current condition) and carried out for 5 years (2046-2050). Overall, the increment of urban ratio under various urban growth scenarios in SMA caused the spatial distributions of temperature to change, the average temperature to increase and the average wind speed to decrease in the

  13. Integrated climate/land use/hydrological change scenarios for assessing threats to ecosystem services on California rangelands

    NASA Astrophysics Data System (ADS)

    Byrd, K. B.; Flint, L. E.; Casey, C. F.; Alvarez, P.; Sleeter, B. M.; Sohl, T.

    2013-12-01

    In California there are over 18 million acres of rangelands in the Central Valley and the interior Coast Range, most of which are privately owned and managed for livestock production. Ranches provide extensive wildlife habitat and generate multiple ecosystem services that carry considerable market and non-market values. These rangelands are under pressure from urbanization and conversion to intensive agriculture, as well as from climate change that can alter the flow of these services. To understand the coupled and isolated impacts of land use and climate change on rangeland ecosystem services, we developed six spatially explicit (250 m) coupled climate/land use/hydrological change scenarios for the Central Valley and oak woodland regions of California consistent with three IPCC emission scenarios - A2, A1B and B1. Three land use land cover (LULC) change scenarios were each integrated with two downscaled global climate models (GCMs) (a warm, wet future and a hot, dry future) and related hydrologic data. We used these scenarios to quantify wildlife habitat, water supply (recharge potential and streamflow) and carbon sequestration on rangelands and to conduct an economic analysis associated with changes in these benefits. The USGS FOREcasting SCEnarios of land-use change model (FORE-SCE), which runs dynamically with downscaled GCM outputs, was used to generate maps of yearly LULC change for each scenario from 2006 to 2100. We used the USGS Basin Characterization Model (BCM), a regional water balance model, to generate change in runoff, recharge, and stream discharge based on land use change and climate change. Metrics derived from model outputs were generated at the landscape scale and for six case-study watersheds. At the landscape scale, over a quarter of the million acres set aside for conservation in the B1 scenario would otherwise be converted to agriculture in the A2 scenario, where temperatures increase by up to 4.5 °C compared to 1.3 °C in the B1 scenario

  14. The climateprediction.net BBC climate change experiment: design of the coupled model ensemble.

    PubMed

    Frame, D J; Aina, T; Christensen, C M; Faull, N E; Knight, S H E; Piani, C; Rosier, S M; Yamazaki, K; Yamazaki, Y; Allen, M R

    2009-03-13

    Perturbed physics experiments are among the most comprehensive ways to address uncertainty in climate change forecasts. In these experiments, parameters and parametrizations in atmosphere-ocean general circulation models are perturbed across ranges of uncertainty, and results are compared with observations. In this paper, we describe the largest perturbed physics climate experiment conducted to date, the British Broadcasting Corporation (BBC) climate change experiment, in which the physics of the atmosphere and ocean are changed, and run in conjunction with a forcing ensemble designed to represent uncertainty in past and future forcings, under the A1B Special Report on Emissions Scenarios (SRES) climate change scenario.

  15. Generating Scenarios When Data Are Missing

    NASA Technical Reports Server (NTRS)

    Mackey, Ryan

    2007-01-01

    The Hypothetical Scenario Generator (HSG) is being developed in conjunction with other components of artificial-intelligence systems for automated diagnosis and prognosis of faults in spacecraft, aircraft, and other complex engineering systems. The HSG accepts, as input, possibly incomplete data on the current state of a system (see figure). The HSG models a potential fault scenario as an ordered disjunctive tree of conjunctive consequences, wherein the ordering is based upon the likelihood that a particular conjunctive path will be taken for the given set of inputs. The computation of likelihood is based partly on a numerical ranking of the degree of completeness of data with respect to satisfaction of the antecedent conditions of prognostic rules. The results from the HSG are then used by a model-based artificial- intelligence subsystem to predict realistic scenarios and states.

  16. Nuclear Futures Analysis and Scenario Building

    SciTech Connect

    Arthur, E.D.; Beller, D.; Canavan, G.H.; Krakowski, R.A.; Peterson, P.; Wagner, R.L.

    1999-07-09

    This LDRD project created and used advanced analysis capabilities to postulate scenarios and identify issues, externalities, and technologies associated with future ''things nuclear''. ''Things nuclear'' include areas pertaining to nuclear weapons, nuclear materials, and nuclear energy, examined in the context of future domestic and international environments. Analysis tools development included adaptation and expansion of energy, environmental, and economics (E3) models to incorporate a robust description of the nuclear fuel cycle (both current and future technology pathways), creation of a beginning proliferation risk model (coupled to the (E3) model), and extension of traditional first strike stability models to conditions expected to exist in the future (smaller force sizes, multipolar engagement environments, inclusion of actual and latent nuclear weapons (capability)). Accomplishments include scenario development for regional and global nuclear energy, the creation of a beginning nuclear architecture designed to improve the proliferation resistance and environmental performance of the nuclear fuel cycle, and numerous results for future nuclear weapons scenarios.

  17. Creating a Scenario Suitable for Multiple Caregivers

    NASA Technical Reports Server (NTRS)

    Doerr, Harold; Bacal, Kira; Hurst, Victor

    2004-01-01

    The HPS can be utilized for the training of a wide variety of caregivers, ranging from physicians to laypeople. Methods: A single scenario was developed and adapted for a number of clinical scenarios and operational environments, ranging from in-flight to the immediate postflight timeline. In this way, different caregivers, from astronauts to search and rescue forces to specialty-boarded physicians, could make use of a single clinical situation. Five crew medical officer analogs and sixty anesthesia residents, serving as flight surgeon analogs, and, were briefed on space medicine and physiology, then were exposed to the scenario and asked to manage the patient as if they were part of the in-flight or recovery team. Results: Basic themes, such as crisis resource management, were standard across the student audiences. Discussion: A single clinical script can easily be adapted for multiple uses.

  18. Projected changes of soil organic carbon in agricultural soils of southeast Germany in the 21th century under different carbon input scenarios

    NASA Astrophysics Data System (ADS)

    Wiesmeier, Martin; Poeplau, Christopher; Sierra, Carlos; Maier, Harald; Hübner, Rico; Kühnel, Anna; Spörlein, Peter; Geuß, Uwe; Hangen, Edzard; Schilling, Bernd; von Lützow, Margit; Kögel-Knabner, Ingrid

    2016-04-01

    As climate change may have a distinct effect on soil organic carbon (SOC) stocks, projections of the future SOC development on larger spatial scales on the basis of soil carbon models are needed. In this study we simulated the SOC development in cropland and grassland soils of Bavaria (southeast Germany) between 2000 and 2095 using the RothC model. At 51 sampling locations detailed model input data as C pools derived by soil fractionation, C input, clay content and climate variables were determined to run the model. Projections for each sampling location were performed on the basis of an average climate scenario (A1B) and three C input scenarios as a realistic range of possible crop yield developments: stagnation of the C input (1) increase by 20% (2) and decrease by 20% (3). The results showed a general decline of SOC stocks of 12% during the 21th century under C input scenario 1 and a decrease of 21% under scenario 3. Remarkably, even the optimistic scenario 2 resulted in a noticeable decline of SOC stocks by 5%. Our study indicated that C inputs in agricultural soils of Bavaria have to increase by 30% until 2095 (given the A1B climate scenario) in order to maintain present SOC stocks. However, projected SOC changes largely depended on the soil unit and regional site characteristics. The modeling approach provides the basis for a further evaluation of changes of the land use management and enables a site-specific delineation of measures for a sustainable supply of soil organic matter under climate change.

  19. Scenarios for the making of vertebrates.

    PubMed

    Holland, Nicholas D; Holland, Linda Z; Holland, Peter W H

    2015-04-23

    Over the past 200 years, almost every invertebrate phylum has been proposed as a starting point for evolving vertebrates. Most of these scenarios are outdated, but several are still seriously considered. The short-range transition from ancestral invertebrate chordates (similar to amphioxus and tunicates) to vertebrates is well accepted. However, longer-range transitions leading up to the invertebrate chordates themselves are more controversial. Opinion is divided between the annelid and the enteropneust scenarios, predicting, respectively, a complex or a simple ancestor for bilaterian animals. Deciding between these ideas will be facilitated by further comparative studies of multicellular animals, including enigmatic taxa such as xenacoelomorphs.

  20. Sectoral trends in global energy use and greenhouse gasemissions

    SciTech Connect

    Price, Lynn; de la Rue du Can, Stephane; Sinton, Jonathan; Worrell, Ernst; Zhou, Nan; Sathaye, Jayant; Levine, Mark

    2006-07-24

    In 2000, the Intergovernmental Panel on Climate Change (IPCC) published a new set of baseline greenhouse gas (GHG) emissions scenarios in the Special Report on Emissions Scenarios (SRES) (Nakicenovic et al., 2000). The SRES team defined four narrative storylines (A1, A2, B1 and B2) describing the relationships between the forces driving GHG and aerosol emissions and their evolution during the 21st century. The SRES reports emissions for each of these storylines by type of GHG and by fuel type to 2100 globally and for four world regions (OECD countries as of 1990, countries undergoing economic reform, developing countries in Asia, rest of world). Specific assumptions about the quantification of scenario drivers, such as population and economic growth, technological change, resource availability, land-use changes, and local and regional environmental policies, are also provided. End-use sector-level results for buildings, industry, or transportation or information regarding adoption of particular technologies and policies are not provided in the SRES. The goal of this report is to provide more detailed information on the SRES scenarios at the end use level including historical time series data and a decomposition of energy consumption to understand the forecast implications in terms of end use efficiency to 2030. This report focuses on the A1 (A1B) and B2 marker scenarios since they represent distinctly contrasting futures. The A1 storyline describes a future of very rapid economic growth, low population growth, and the rapid introduction of new and more efficient technologies. Major underlying themes are convergence among regions, capacity building, and increased cultural and social interactions, with a substantial reduction in regional differences in per capita income. The B2 storyline describes a world with an emphasis on economic, social, and environmental sustainability, especially at the local and regional levels. It is a world with moderate population growth

  1. Maximising the Effectiveness of a Scenario Planning Process: Tips for Scenario Planners in Higher Education

    ERIC Educational Resources Information Center

    Sayers, Nicola

    2011-01-01

    Scenario planning is a tool which can help organisations and people to think about, and plan for, the long-term future. In basic terms, it involves creating a number of in-depth scenarios (stories), each of which tells of a different possible future for an organisation or issue, and considering how each different future might influence…

  2. Optimizing Decision Preparedness by Adapting Scenario Complexity and Automating Scenario Generation

    NASA Technical Reports Server (NTRS)

    Dunne, Rob; Schatz, Sae; Flore, Stephen M.; Nicholson, Denise

    2011-01-01

    Klein's recognition-primed decision (RPD) framework proposes that experts make decisions by recognizing similarities between current decision situations and previous decision experiences. Unfortunately, military personnel arQ often presented with situations that they have not experienced before. Scenario-based training (S8T) can help mitigate this gap. However, SBT remains a challenging and inefficient training approach. To address these limitations, the authors present an innovative formulation of scenario complexity that contributes to the larger research goal of developing an automated scenario generation system. This system will enable trainees to effectively advance through a variety of increasingly complex decision situations and experiences. By adapting scenario complexities and automating generation, trainees will be provided with a greater variety of appropriately calibrated training events, thus broadening their repositories of experience. Preliminary results from empirical testing (N=24) of the proof-of-concept formula are presented, and future avenues of scenario complexity research are also discussed.

  3. High Resolution Spectroscopy of A^1B1u ← X^1A_g 8^1_04^1_0 Band of Naphthalene Referenced to AN Optical Frequency Comb

    NASA Astrophysics Data System (ADS)

    Nakashima, Kazuki; Nishiyama, Akiko; Misono, Masatoshi

    2016-06-01

    In the excited vibronic states of naphthalene, there exist various interesting interactions such as intramolecular vibrational energy redistribution (IVR), intersystem crossing (ISC), and internal conversion (IC). More than thirty yeas ago, Beck et al. showed that IVR became remarkable when the excess energy exceeded about 2000 cm-1^, ^a. In the present study, we observe Doppler-free two-photon absorption spectra of A^1B1u ← X^1A_g 8^1_04^1_0 band of naphthalene around 34281 cm-1. The excess energy is 2261 cm-1, which is just above the threshold of IVR. Thus we expect this band is suitable to analyze the dynamics in the excited vibronic states. In our experiment, the spectral resolution is about 100 kHz, and rovibronic lines are well-resolved. To decide the transition frequencies, frequency shifts, and spectral linewidths with high accuracy and precision, we employed the comb-referenced Doppler-free two-photon absorption spectroscopic system^b. We proceed to assign the rovibronic lines in ^qQ transition, and to determine molecular constants in the excited vibronic state. ^a S. M. Beck, J. B. Hopkins, D. E. Powers, and R. E. Smalley, J. Chem. Phys. 74, 43(1981). ^b A. Nishiyama, K. Nakashima, A. Matsuba, and M. Misono, J. Mol. Spectrosc. 318, 40 (2015).

  4. Co-segregation of Freiberg's infraction with a familial translocation t(5;7)(p13.3;p22.2) ascertained by a child with cri du chat syndrome and brachydactyly type A1B.

    PubMed

    Myśliwiec, Marta; Panasiuk, Barbara; Dębiec-Rychter, Maria; Iwanowski, Piotr Sebastian; Łebkowska, Urszula; Nowakowska, Beata; Marcinkowska, Anna; Stankiewicz, Pawel; Midro, Alina T

    2015-02-01

    The identification of chromosomal breakpoints in association with human abnormal phenotypes can enable elucidation of gene function. We report on epiphyseal aseptic necrosis of the lesser head of the second metatarsal bone, known as Freiberg's infraction (FI), in two female carriers of the apparently balanced t(5;7)(p13.3;p22.2) ascertained by a 16-year-old girl with cri-du-chat syndrome and unusual skeletal features in association with an unbalanced translocation der(5) t(5;7)(p13.3;p22.2). Mapping of the chromosome breakpoints using fluorescent in situ hybridization (FISH) narrowed them to the coding sequence of ADAMTS12 on chromosome 5p13.3 and SDK1 on 7p22.2. In addition, several skeletal abnormalities classified as brachydactyly type A1B (BDA1B) were present in the proband and in both carriers of t(5;7)(p13.3;p22.2), suggesting a potential role of ADAMTS12 in the development of the BDA1B observed in this family.

  5. Determination of loperamide in mdr1a/1b knock-out mouse brain tissue using matrix-assisted laser desorption/ionization mass spectrometry and comparison with quantitative electrospray-triple quadrupole mass spectrometry analysis.

    PubMed

    Shin, Young G; Dong, Teresa; Chou, Bilin; Menghrajani, Kapil

    2011-11-01

    Recently matrix-assisted laser desorption/ionization mass spectrometry (MALDI MS) imaging has been used to analyze small molecule pharmaceutical compounds directly on tissue sections to determine spatial distribution within target tissue and organs. The data presented to date usually indicate relative amounts of drug within the tissue. The determination of absolute amounts is still done using tissue homogenization followed by traditional liquid chromatography-tandem mass spectrometry (LC-MS/MS). In this study, the quantitative determination of loperamide, an antidiarrheal agent and a P-glycoprotein substrate, in mdr1a/1b (-/-) mouse brain tissue sections using MALDI MS on a quadrupole time-of-flight mass spectrometry is described. 5 mg/mL α-cyano-4-hydroxycinnamic acid in 50% acetonitrile with 0.1% trifluoroacetic acid and 0.5 μM reserpine was used as the MALDI matrix. The calibration curve constructed by the peak intensities of standard samples from MALDI MS was linear from 0.025 to 0.5 μM with r² = 0.9989. The accuracy of calibration curve standards was 78.3-105.9% and the percent deviation was less than 25%. Comparison between direct MALDI tissue analysis and conventional tissue analysis using homogenization followed by electrospray LC-MS/MS was also explored.

  6. Rapid detection of HCV genotyping 1a, 1b, 2a, 3a, 3b and 6a in a single reaction using two-melting temperature codes by a real-time PCR-based assay.

    PubMed

    Athar, Muhammad Ammar; Xu, Ye; Xie, Xiaoting; Xu, Zhenxing; Ahmad, Vakil; Hayder, Zulfiqar; Hussain, Syed Sajid; Liao, Yiqun; Li, Qingge

    2015-09-15

    The genotype of the hepatitis C virus (HCV) is an important indicator for antiviral therapeutic response. We hereby described development of a rapid HCV genotyping approach that enabled the identification of the six most common HCV subtypes of Asia, i.e., 1a, 1b, 2a, 3a, 3b, and 6a, in a single reaction. Using two dual-labeled, self-quenched probes that target the core region of the HCV genome, the exact subtype could be accurately identified by two-melting temperature codes determined from the two respective probes in a real-time PCR assay. Analytical sensitivity studies using armored RNA samples representing each of the six HCV subtypes showed that 5 copies/reaction of HCV RNA could be detected. The assay was evaluated using 244 HCV-positive serum samples and the results were compared with sequencing analysis. Of the 224 samples, subtype 3a (127, 52.3%) was the dominant, followed by 1b (51, 20.9%), 3b (47, 19.3%), 2a (8, 3.3%), 6a (4, 1.6%) and the least was subtype 1a (1, 0.4%). Moreover, 6 (2.5%) mixed infection samples were also detected. These results were fully concordant with sequencing analysis. We concluded that this real-time PCR-based assay could provide a rapid and reliable tool for routine HCV genotyping in most Asian countries.

  7. When things do not go as expected: scenario life savers.

    PubMed

    Dieckmann, Peter; Lippert, Anne; Glavin, Ronnie; Rall, Marcus

    2010-08-01

    In this paper we discuss scenario life savers - interventions before and during simulation scenarios that allow to create and use relevant learning opportunities, even if unexpected events happen during the conduction of the scenario. Scenario life savers are needed, when the comprehension or acceptance of the scenario by the participants is at stake, thus compromising learning opportunities. Scenario life savers can principally work by bringing participants back on track of the planned scenario or by adapting the conduction to their actions on the fly. Interventions can be within the logic of the scenario or from the "outside," not being part of the scenario itself. Scenario life savers should be anticipated during the design of scenarios and used carefully during their conduction, aiming to maximize the learning for participants.

  8. Global climate simulations with the A1F1 scenario for 2000-2100: Meltwater, temperature and river flow impacts in India

    NASA Astrophysics Data System (ADS)

    Erickson, D. J.; Branstetter, M. L.; Wilbanks, T. J.; Ganguly, A. R.; Hoffman, F. M.; King, A. W.; Buja, L.; Panwar, T. S.

    2008-05-01

    Climate simulations based on the assumptions implicit in the SRES A1F1 scenario for the period 2000-2100 using CCSM3 are analyzed. We find temperature increases of 3-9oC over Northern India by the end of this century. We will discuss the implications and resulting alterations of the hydrologic cycle as the climate evolves from 2000-2100. In particular, we will assess the changes in the surface latent and sensible heat energy budget, the Indian regional water budgets including trends in the timing and duration of the Indian monsoon and the resulting impacts on mean river flow and hydroelectric power generation potential. These analyses will also be examined within the context of heat index, droughts, floods and related estimates of societal robustness and resiliency. We will compare our new insights with the existing literature. Climate simulations based on the SRES A2 and B1 scenarios forced with land cover have indicated increased cloud cover and precipitation, resulting in decreased incident radiation and higher latent heat fluxes, in India during June, July and August by 2050 (Feddema et al., 2005). Analyses of historical records in the context of the Indian Monsoon Rainfall (IMR) have suggested an evolving relation of IMR with natural climate variability caused by El Nino events (Krishna Kumar et al., 2006), studied the combined effects of natural climate variability and global warming (Kripalini et al., 2003) on IMR, as well as demonstrated an increasing trend of extreme rain events in a warming environment (Goswami et al., 2006). In addition, the vulnerability of the Indian agriculture sector to climate change was analyzed and mapped at district-levels by combining with multiple global stressors (O'Brien et al., 2004). [[References::: (1) Feddema, J.J., Oleson, K.W., Bonan, G.B., Mearns, L.O., Buja, L.E., Meehl, G.A., and W.M. Washington (2005): The importance of land-cover change in simulating future climates, Science, 310 (5754): 1674-1678, 9 December

  9. Future Scenarios for Mobile Science Learning

    ERIC Educational Resources Information Center

    Burden, Kevin; Kearney, Matthew

    2016-01-01

    This paper adopts scenario planning as a methodological approach and tool to help science educators reconceptualise their use of mobile technologies across various different futures. These "futures" are set out neither as predictions nor prognoses but rather as stimuli to encourage greater discussion and reflection around the use of…

  10. Wiki Based Collaborative Learning in Interuniversity Scenarios

    ERIC Educational Resources Information Center

    Katzlinger, Elisabeth; Herzog, Michael A.

    2014-01-01

    In business education advanced collaboration skills and media literacy are important for surviving in a globalized business where virtual communication between enterprises is part of the day-by-day business. To transform these global working situations into higher education, a learning scenario between two universities in Germany and Austria was…

  11. Using Scenarios and Simulations to Plan Colleges

    ERIC Educational Resources Information Center

    McIntyre, Chuck

    2004-01-01

    Using a case study, this article describes a method by which higher education institutions construct and use multiple future scenarios and simulations to plan strategically: to create visions of their futures, chart broad directions (mission and goals), and select learning and delivery strategies so as to achieve those broad directions. The…

  12. Flooding Capability for River-based Scenarios

    SciTech Connect

    Smith, Curtis L.; Prescott, Steven; Ryan, Emerald; Calhoun, Donna; Sampath, Ramprasad; Anderson, S. Danielle; Casteneda, Cody

    2015-10-01

    This report describes the initial investigation into modeling and simulation tools for application of riverine flooding representation as part of the Risk-Informed Safety Margin Characterization (RISMC) Pathway external hazards evaluations. The report provides examples of different flooding conditions and scenarios that could impact river and watershed systems. Both 2D and 3D modeling approaches are described.

  13. Linguistic evaluation of terrorist scenarios: example application.

    SciTech Connect

    Darby, John L.

    2007-03-01

    In 2005, a group of international decision makers developed a manual process for evaluating terrorist scenarios. That process has been implemented in the approximate reasoning Java software tool, LinguisticBelief, released in FY2007. One purpose of this report is to show the flexibility of the LinguisticBelief tool to automate a custom model developed by others. LinguisticBelief evaluates combinations of linguistic variables using an approximate reasoning rule base. Each variable is comprised of fuzzy sets, and a rule base describes the reasoning on combinations of variables fuzzy sets. Uncertainty is considered and propagated through the rule base using the belief/plausibility measure. This report documents the evaluation and rank-ordering of several example terrorist scenarios for the existing process implemented in our software. LinguisticBelief captures and propagates uncertainty and allows easy development of an expanded, more detailed evaluation, neither of which is feasible using a manual evaluation process. In conclusion, the Linguistic-Belief tool is able to (1) automate an expert-generated reasoning process for the evaluation of the risk of terrorist scenarios, including uncertainty, and (2) quickly evaluate and rank-order scenarios of concern using that process.

  14. Chemical Data Reporting Byproduct and Recycling Scenarios

    EPA Pesticide Factsheets

    This document addresses a series of 18 industry scenarios and questions related to EPA’s Chemical Data Reporting (CDR) rule. The primary goal of this document is to help the regulated community comply with the requirements of the CDR rule.

  15. Probabilistic Simulation of Territorial Seismic Scenarios

    SciTech Connect

    Baratta, Alessandro; Corbi, Ileana

    2008-07-08

    The paper is focused on a stochastic process for the prevision of seismic scenarios on the territory and developed by means of some basic assumptions in the procedure and by elaborating the fundamental parameters recorded during some ground motions occurred in a seismic area.

  16. Probabilistic Simulation of Territorial Seismic Scenarios

    NASA Astrophysics Data System (ADS)

    Baratta, Alessandro; Corbi, Ileana

    2008-07-01

    The paper is focused on a stochastic process for the prevision of seismic scenarios on the territory and developed by means of some basic assumptions in the procedure and by elaborating the fundamental parameters recorded during some ground motions occurred in a seismic area.

  17. National FCEV and Hydrogen Fueling Station Scenarios

    SciTech Connect

    Bush, Brian; Melaina, Marc

    2016-06-09

    This presentation provides a summary of the FY16 activities and accomplishments for NREL's national fuel cell electric vehicle (FCEV) and hydrogen fueling station scenarios project. It was presented at the U.S. Department of Energy Hydrogen and Fuel Cells Program 2016 Annual Merit Review and Peer Evaluation Meeting on June 9, 2016, in Washington, D.C.

  18. Beyond Data: The World of Scenario Planning.

    ERIC Educational Resources Information Center

    Goens, George A.

    2001-01-01

    Leadership involves more than analyzing data and making decisions. Even the most strategically made plans can be circumvented by people or unanticipated events. Scenario planning allows administrators to weave various components (driving forces, predetermined elements, and critical uncertainties) into plausible stories of what futures can unfold.…

  19. Future Scenarios for Mobile Science Learning

    ERIC Educational Resources Information Center

    Burden, Kevin; Kearney, Matthew

    2016-01-01

    This paper adopts scenario planning as a methodological approach and tool to help science educators reconceptualise their use of mobile technologies across various different futures. These "futures" are set out neither as predictions nor prognoses but rather as stimuli to encourage greater discussion and reflection around the use of…

  20. Risk Appraisal in Scripted Acquaintance Rape Scenarios.

    ERIC Educational Resources Information Center

    Wright, Doris J.

    Cognitive appraisals are believed to influence how women judge or appraise risk in acquaintance interactions which lead to sexual assault. Ways in which men and women judge the presence of risk factors in scripted acquaintance rape scenarios, and whether alcohol was a significant factor in assessing risk, are examined in this paper. Participants…

  1. Interactive, multiobjective Bayesian optimization of tokamak scenarios

    NASA Astrophysics Data System (ADS)

    Urban, Jakub; Artaud, Jean-François

    2016-10-01

    Bayesian optimization is applied to tokamak scenario optimizations. The key advantages are 1) a reduced number of objective function evaluations, 2) no need for derivatives, and 3) the possibility to include a prior knowledge. This is of a great value for optimizing tokamak scenarios, where several (competing) objectives with often unknown magnitudes exist and the number of parameters is large (>10). The first two properties imply that Bayesian optimization is well suited for heavy, complex objective functions. Reusing previous iterations as priors for next optimization steps effectively enables interactive, multiobjective optimizations, regardless of whether a human decision maker is included or not. We show that these features make Bayesian optimization an outstanding tool for optimizing tokamak scenarios. Objective functions and constraints, targeting, e.g., fusion gain, flux consumption, coils currents limits or q-profile, can be assembled interactively. The optimized parameter vector may include actuators like plasma current or heating waveforms. We demonstrate the capabilities on optimizing ITER and DEMO-like scenarios, simulated by the METIS code.

  2. Scenario Development for Information Operations (IO) Experimentation

    DTIC Science & Technology

    2003-07-10

    valid OMB control number. 1. REPORT DATE 01 OCT 2003 2. REPORT TYPE N/A 3. DATES COVERED - 4. TITLE AND SUBTITLE Scenario Development for...country called DYSLEXIA , whose government has been making threats to invade and appropriate a region of its neighbouring country, ABSTEMIA, which is

  3. Ethics Scenarios: A Critical Theory Symposium.

    ERIC Educational Resources Information Center

    Anderson, Jane; And Others

    This symposium chaired by John C. Belland addressed the ethical position of educational communications and technology in society. Presenters created ethics scenarios and applied critical theory to provide insight. Intended to stimulate questions, the approach was philosophical, literary, and sociopolitical, and reflected Derrida, Foucault, and…

  4. Biomass round bales infield aggregation logistic scenarios

    USDA-ARS?s Scientific Manuscript database

    Biomass bales often need to be aggregated (collected into groups and transported) to a field-edge stack for temporary storage for feedlots or processing facilities. Aggregating the bales with the least total distance involved is a goal of producers and bale handlers. Several logistics scenarios for ...

  5. Ethics Scenarios: A Critical Theory Symposium.

    ERIC Educational Resources Information Center

    Anderson, Jane; And Others

    This symposium chaired by John C. Belland addressed the ethical position of educational communications and technology in society. Presenters created ethics scenarios and applied critical theory to provide insight. Intended to stimulate questions, the approach was philosophical, literary, and sociopolitical, and reflected Derrida, Foucault, and…

  6. Iterative Mechanism Solutions with Scenario and ADAMS

    NASA Technical Reports Server (NTRS)

    Rhoades, Daren

    2006-01-01

    This slide presentation reviews the use of iterative solutions using Scenario for Motion (UG NX 2 Motion) to assist in designing the Mars Science Laboratory (MSL). The MSL will have very unique design requirements, and in order to meet these requirements the system must have the ability to design for static stability, simulate mechanism kinematics, simulate dynamic behaviour and be capable of reconfiguration, and iterations as designed. The legacy process used on the Mars Exploration rovers worked, but it was cumbersome using multiple tools, limited configuration control, with manual process and communication, and multiple steps. The aim is to develop a mechanism that would reduce turn around time, and make more reiterations possible, to improve the quality and quantity of data, and to enhance configuration control. Currently for NX Scenario for Motion uses are in the articulation studies, the simulations of traverse motions,and subsystem simulations. The design of the Rover landing model requires accurate results, flexible elements, such as beams, and the use of the full ADAMS solver has been used. In order to achieve this, when required, there has been a direct translation from Scenario to ADAMS, with additional data in ascii format. The process that has been designed to move from Scenario to ADAMS is reviewed.

  7. Iterative Mechanism Solutions with Scenario and ADAMS

    NASA Technical Reports Server (NTRS)

    Rhoades, Daren

    2006-01-01

    This slide presentation reviews the use of iterative solutions using Scenario for Motion (UG NX 2 Motion) to assist in designing the Mars Science Laboratory (MSL). The MSL will have very unique design requirements, and in order to meet these requirements the system must have the ability to design for static stability, simulate mechanism kinematics, simulate dynamic behaviour and be capable of reconfiguration, and iterations as designed. The legacy process used on the Mars Exploration rovers worked, but it was cumbersome using multiple tools, limited configuration control, with manual process and communication, and multiple steps. The aim is to develop a mechanism that would reduce turn around time, and make more reiterations possible, to improve the quality and quantity of data, and to enhance configuration control. Currently for NX Scenario for Motion uses are in the articulation studies, the simulations of traverse motions,and subsystem simulations. The design of the Rover landing model requires accurate results, flexible elements, such as beams, and the use of the full ADAMS solver has been used. In order to achieve this, when required, there has been a direct translation from Scenario to ADAMS, with additional data in ascii format. The process that has been designed to move from Scenario to ADAMS is reviewed.

  8. Competency-Based Teacher Education: A Scenario.

    ERIC Educational Resources Information Center

    Weber, Wilford A.; Cooper, James M.

    This fictitious scenario embodies all the characteristics and dimensions for a fully developed competency-based teacher education program envisioned by the authors. A single program and its implications for students, faculty, and the institution are presented. Specific areas of the program covered 1) a fundamental description of the competency…

  9. Use of simplifier scenarios for CRM training

    NASA Technical Reports Server (NTRS)

    Weatherly, D.

    1984-01-01

    Cockpit resource management (CRM) at Metro Airlines is discussed. The process by which the program of CRM training was initiated is mentioned. Management aspects of various flying scenarios are considered. The transfer of training from the classroom to the field is assessed.

  10. Emissions Scenarios and Fossil-fuel Peaking

    NASA Astrophysics Data System (ADS)

    Brecha, R.

    2008-12-01

    Intergovernmental Panel on Climate Change (IPCC) emissions scenarios are based on detailed energy system models in which demographics, technology and economics are used to generate projections of future world energy consumption, and therefore, of greenhouse gas emissions. Built into the assumptions for these scenarios are estimates for ultimately recoverable resources of various fossil fuels. There is a growing chorus of critics who believe that the true extent of recoverable fossil resources is much smaller than the amounts taken as a baseline for the IPCC scenarios. In a climate optimist camp are those who contend that "peak oil" will lead to a switch to renewable energy sources, while others point out that high prices for oil caused by supply limitations could very well lead to a transition to liquid fuels that actually increase total carbon emissions. We examine a third scenario in which high energy prices, which are correlated with increasing infrastructure, exploration and development costs, conspire to limit the potential for making a switch to coal or natural gas for liquid fuels. In addition, the same increasing costs limit the potential for expansion of tar sand and shale oil recovery. In our qualitative model of the energy system, backed by data from short- and medium-term trends, we have a useful way to gain a sense of potential carbon emission bounds. A bound for 21st century emissions is investigated based on two assumptions: first, that extractable fossil-fuel resources follow the trends assumed by "peak oil" adherents, and second, that little is done in the way of climate mitigation policies. If resources, and perhaps more importantly, extraction rates, of fossil fuels are limited compared to assumptions in the emissions scenarios, a situation can arise in which emissions are supply-driven. However, we show that even in this "peak fossil-fuel" limit, carbon emissions are high enough to surpass 550 ppm or 2°C climate protection guardrails. Some

  11. Scenarios Based on Shared Socioeconomic Pathway Assumptions

    NASA Astrophysics Data System (ADS)

    Edmonds, J.

    2013-12-01

    A set of new scenarios is being developed by the international scientific community as part of a larger program that was articulated in Moss, et al. (2009), published in Nature. A long series of meetings including climate researchers drawn from the climate modeling, impacts, adaptation and vulnerability (IAV) and integrated assessment modeling (IAM) communities have led to the development of a set of five Shared Socioeconomic Pathways (SSPs), which define the state of human and natural societies at a macro scale over the course of the 21st century without regard to climate mitigation or change. SSPs were designed to explore a range of possible futures consistent with greater or lesser challenges to mitigation and challenges to adaptation. They include a narrative storyline and a set of quantified measures--e.g. demographic and economic profiles--that define the high-level state of society as it evolves over the 21st century under the assumption of no significant climate feedback. SSPs can be used to develop quantitative scenarios of human Earth systems using IAMs. IAMs produce information about greenhouse gas emissions, energy systems, the economy, agriculture and land use. Each set of SSPs will have a different human Earth system realization for each IAM. Five groups from the IAM community have begun to explore the implications of SSP assumptions for emissions, energy, economy, agriculture and land use. We report the quantitative results of initial experiments from those groups. A major goal of the Moss, et al. strategy was to enable the use of CMIP5 climate model ensemble products for IAV research. CMIP5 climate scenarios used four Representative Concentration Pathway (RCP) scenarios, defined in terms of radiative forcing in the year 2100: 2.6, 4.5, 6.0, and 8.5 Wm-2. There is no reason to believe that the SSPs will generate year 2100 levels of radiative forcing that correspond to the four RCP levels, though it is important that at least one SSP produce a

  12. Generating moment matching scenarios using optimization techniques

    DOE PAGES

    Mehrotra, Sanjay; Papp, Dávid

    2013-05-16

    An optimization based method is proposed to generate moment matching scenarios for numerical integration and its use in stochastic programming. The main advantage of the method is its flexibility: it can generate scenarios matching any prescribed set of moments of the underlying distribution rather than matching all moments up to a certain order, and the distribution can be defined over an arbitrary set. This allows for a reduction in the number of scenarios and allows the scenarios to be better tailored to the problem at hand. The method is based on a semi-infinite linear programming formulation of the problem thatmore » is shown to be solvable with polynomial iteration complexity. A practical column generation method is implemented. The column generation subproblems are polynomial optimization problems; however, they need not be solved to optimality. It is found that the columns in the column generation approach can be efficiently generated by random sampling. The number of scenarios generated matches a lower bound of Tchakaloff's. The rate of convergence of the approximation error is established for continuous integrands, and an improved bound is given for smooth integrands. Extensive numerical experiments are presented in which variants of the proposed method are compared to Monte Carlo and quasi-Monte Carlo methods on both numerical integration problems and stochastic optimization problems. The benefits of being able to match any prescribed set of moments, rather than all moments up to a certain order, is also demonstrated using optimization problems with 100-dimensional random vectors. Here, empirical results show that the proposed approach outperforms Monte Carlo and quasi-Monte Carlo based approaches on the tested problems.« less

  13. Generating moment matching scenarios using optimization techniques

    SciTech Connect

    Mehrotra, Sanjay; Papp, Dávid

    2013-05-16

    An optimization based method is proposed to generate moment matching scenarios for numerical integration and its use in stochastic programming. The main advantage of the method is its flexibility: it can generate scenarios matching any prescribed set of moments of the underlying distribution rather than matching all moments up to a certain order, and the distribution can be defined over an arbitrary set. This allows for a reduction in the number of scenarios and allows the scenarios to be better tailored to the problem at hand. The method is based on a semi-infinite linear programming formulation of the problem that is shown to be solvable with polynomial iteration complexity. A practical column generation method is implemented. The column generation subproblems are polynomial optimization problems; however, they need not be solved to optimality. It is found that the columns in the column generation approach can be efficiently generated by random sampling. The number of scenarios generated matches a lower bound of Tchakaloff's. The rate of convergence of the approximation error is established for continuous integrands, and an improved bound is given for smooth integrands. Extensive numerical experiments are presented in which variants of the proposed method are compared to Monte Carlo and quasi-Monte Carlo methods on both numerical integration problems and stochastic optimization problems. The benefits of being able to match any prescribed set of moments, rather than all moments up to a certain order, is also demonstrated using optimization problems with 100-dimensional random vectors. Here, empirical results show that the proposed approach outperforms Monte Carlo and quasi-Monte Carlo based approaches on the tested problems.

  14. Global crop yield reductions due to surface ozone exposure: 2. Year 2030 potential crop production losses and economic damage under two scenarios of O 3 pollution

    NASA Astrophysics Data System (ADS)

    Avnery, Shiri; Mauzerall, Denise L.; Liu, Junfeng; Horowitz, Larry W.

    2011-04-01

    We examine the potential global risk of increasing surface ozone (O 3) exposure to three key staple crops (soybean, maize, and wheat) in the near future (year 2030) according to two trajectories of O 3 pollution: the Intergovernmental Panel on Climate Change Special Report on Emissions Scenarios (IPCC SRES) A2 and B1 storylines, which represent upper- and lower-boundary projections, respectively, of most O 3 precursor emissions in 2030. We use simulated hourly O 3 concentrations from the Model for Ozone and Related Chemical Tracers version 2.4 (MOZART-2), satellite-derived datasets of agricultural production, and field-based concentration:response relationships to calculate crop yield reductions resulting from O 3 exposure. We then calculate the associated crop production losses and their economic value. We compare our results to the estimated impact of O 3 on global agriculture in the year 2000, which we assessed in our companion paper [Avnery et al., 2011]. In the A2 scenario we find global year 2030 yield loss of wheat due to O 3 exposure ranges from 5.4 to 26% (a further reduction in yield of +1.5-10% from year 2000 values), 15-19% for soybean (reduction of +0.9-11%), and 4.4-8.7% for maize (reduction of +2.1-3.2%) depending on the metric used, with total global agricultural losses worth 17-35 billion USD 2000 annually (an increase of +6-17 billion in losses from 2000). Under the B1 scenario, we project less severe but still substantial reductions in yields in 2030: 4.0-17% for wheat (a further decrease in yield of +0.1-1.8% from 2000), 9.5-15% for soybean (decrease of +0.7-1.0%), and 2.5-6.0% for maize (decrease of + 0.3-0.5%), with total losses worth 12-21 billion annually (an increase of +1-3 billion in losses from 2000). Because our analysis uses crop data from the year 2000, which likely underestimates agricultural production in 2030 due to the need to feed a population increasing from approximately 6 to 8 billion people between 2000 and 2030, our

  15. Future Flood Inundation and Damages from Storm Surge in the Coast of Virginia and Maryland with Projected Climate Change and Sea Level Rise Scenarios

    NASA Astrophysics Data System (ADS)

    Rezaie, A. M.; Ferreira, C.; Walls, M. A.

    2016-12-01

    The recurrent flood risks on coastal areas in the United States (US) due to hurricane wind and storm surge are likely to rise with warmer climate, frequent storms, and increasing coastal population. Recent studies suggested that the global financial losses from hurricanes will be doubled by 2100 due to combined impact of climate change, sea level rise (SLR) and intensified hurricanes. While the predicted average SLR for the Mid-Atlantic region of the US is 2.2 meter, some coastal areas in Virginia (VA) and Maryland (MD) are expected to experience a 0.7 to 1.6m and 0.6 to 1.7m SLR respectively. Nearly 80 percent of the total $5.3 billion property damage by Hurricane Isabel in 2003 was within VA and MD. In order to provide a quantitative assessment of the future flooding and associated damages for projected climate change and SLR scenarios, this study integrated state-of-the-art coastal numerical model ADCIRC with a careful economic valuation exercise of flood damages. The study area covers the entire coastal zone of VA and MD focusing on regions that are in the vicinity of the Chesapeake Bay and the Atlantic Ocean with high susceptibility to storm surge and flooding. Multiple climate change land cover scenarios generated by the United States Geological Survey (USGS) under a series of the IPCC's Emissions Scenarios are incorporated in the modeling approach to integrate climate change whereas local SLR projections are included to provide the regional aspects of future risks. Preliminary results for hurricane Isabel (2003) shows that a 2.3m rise in sea level can cause storm surges rising up to 3-4m in the coastal areas. While a 0.5m SLR makes the range 1-2.5m in the affected areas. It is also seen that higher increase in the sea level not only causes higher range of inundation but a greater extent of flood as well. The projected inland flooding extents are highest for the SRES A2 Scenario. Alongside an estimate of future loss and damage will be prepared to assist in

  16. The Scenario Model Intercomparison Project (ScenarioMIP) for CMIP6

    SciTech Connect

    O'Neill, Brian C.; Tebaldi, Claudia; van Vuuren, Detlef P.; Eyring, Veronika; Friedlingstein, Pierre; Hurtt, George; Knutti, Reto; Kriegler, Elmar; Lamarque, Jean-Francois; Lowe, Jason; Meehl, Gerald A.; Moss, Richard; Riahi, Keywan; Sanderson, Benjamin M.

    2016-01-01

    Projections of future climate change play a fundamental role in improving understanding of the climate system as well as characterizing societal risks and response options. The Scenario Model Intercomparison Project (ScenarioMIP) is the primary activity within Phase 6 of the Coupled Model Intercomparison Project (CMIP6) that will provide multi-model climate projections based on alternative scenarios of future emissions and land use changes produced with integrated assessment models. In this paper, we describe ScenarioMIP's objectives, experimental design, and its relation to other activities within CMIP6. The ScenarioMIP design is one component of a larger scenario process that aims to facilitate a wide range of integrated studies across the climate science, integrated assessment modeling, and impacts, adaptation, and vulnerability communities, and will form an important part of the evidence base in the forthcoming Intergovernmental Panel on Climate Change (IPCC) assessments. At the same time, it will provide the basis for investigating a number of targeted science and policy questions that are especially relevant to scenario-based analysis, including the role of specific forcings such as land use and aerosols, the effect of a peak and decline in forcing, the consequences of scenarios that limit warming to below 2 °C, the relative contributions to uncertainty from scenarios, climate models, and internal variability, and long-term climate system outcomes beyond the 21st century. To serve this wide range of scientific communities and address these questions, a design has been identified consisting of eight alternative 21st century scenarios plus one large initial condition ensemble and a set of long-term extensions, divided into two tiers defined by relative priority. Some of these scenarios will also provide a basis for variants planned to be run in other CMIP6-Endorsed MIPs to investigate questions related to specific forcings. Harmonized, spatially explicit

  17. The Scenario Model Intercomparison Project (ScenarioMIP) for CMIP6

    DOE PAGES

    O'Neill, Brian C.; Tebaldi, Claudia; van Vuuren, Detlef P.; ...

    2016-09-28

    Projections of future climate change play a fundamental role in improving understanding of the climate system as well as characterizing societal risks and response options. The Scenario Model Intercomparison Project (ScenarioMIP) is the primary activity within Phase 6 of the Coupled Model Intercomparison Project (CMIP6) that will provide multi-model climate projections based on alternative scenarios of future emissions and land use changes produced with integrated assessment models. Here, we describe ScenarioMIP's objectives, experimental design, and its relation to other activities within CMIP6. The ScenarioMIP design is one component of a larger scenario process that aims to facilitate a wide rangemore » of integrated studies across the climate science, integrated assessment modeling, and impacts, adaptation, and vulnerability communities, and will form an important part of the evidence base in the forthcoming Intergovernmental Panel on Climate Change (IPCC) assessments. Furthermore, it will provide the basis for investigating a number of targeted science and policy questions that are especially relevant to scenario-based analysis, including the role of specific forcings such as land use and aerosols, the effect of a peak and decline in forcing, the consequences of scenarios that limit warming to below 2°C, the relative contributions to uncertainty from scenarios, climate models, and internal variability, and long-term climate system outcomes beyond the 21st century. In order to serve this wide range of scientific communities and address these questions, a design has been identified consisting of eight alternative 21st century scenarios plus one large initial condition ensemble and a set of long-term extensions, divided into two tiers defined by relative priority. Some of these scenarios will also provide a basis for variants planned to be run in other CMIP6-Endorsed MIPs to investigate questions related to specific forcings. Harmonized, spatially explicit

  18. The Scenario Model Intercomparison Project (ScenarioMIP) for CMIP6

    SciTech Connect

    O'Neill, Brian C.; Tebaldi, Claudia; van Vuuren, Detlef P.; Eyring, Veronika; Friedlingstein, Pierre; Hurtt, George; Knutti, Reto; Kriegler, Elmar; Lamarque, Jean-Francois; Lowe, Jason; Meehl, Gerald A.; Moss, Richard; Riahi, Keywan; Sanderson, Benjamin M.

    2016-09-28

    Projections of future climate change play a fundamental role in improving understanding of the climate system as well as characterizing societal risks and response options. The Scenario Model Intercomparison Project (ScenarioMIP) is the primary activity within Phase 6 of the Coupled Model Intercomparison Project (CMIP6) that will provide multi-model climate projections based on alternative scenarios of future emissions and land use changes produced with integrated assessment models. Here, we describe ScenarioMIP's objectives, experimental design, and its relation to other activities within CMIP6. The ScenarioMIP design is one component of a larger scenario process that aims to facilitate a wide range of integrated studies across the climate science, integrated assessment modeling, and impacts, adaptation, and vulnerability communities, and will form an important part of the evidence base in the forthcoming Intergovernmental Panel on Climate Change (IPCC) assessments. Furthermore, it will provide the basis for investigating a number of targeted science and policy questions that are especially relevant to scenario-based analysis, including the role of specific forcings such as land use and aerosols, the effect of a peak and decline in forcing, the consequences of scenarios that limit warming to below 2°C, the relative contributions to uncertainty from scenarios, climate models, and internal variability, and long-term climate system outcomes beyond the 21st century. In order to serve this wide range of scientific communities and address these questions, a design has been identified consisting of eight alternative 21st century scenarios plus one large initial condition ensemble and a set of long-term extensions, divided into two tiers defined by relative priority. Some of these scenarios will also provide a basis for variants planned to be run in other CMIP6-Endorsed MIPs to investigate questions related to specific forcings. Harmonized, spatially explicit

  19. The Scenario Model Intercomparison Project (ScenarioMIP) for CMIP6

    NASA Astrophysics Data System (ADS)

    O'Neill, Brian C.; Tebaldi, Claudia; van Vuuren, Detlef P.; Eyring, Veronika; Friedlingstein, Pierre; Hurtt, George; Knutti, Reto; Kriegler, Elmar; Lamarque, Jean-Francois; Lowe, Jason; Meehl, Gerald A.; Moss, Richard; Riahi, Keywan; Sanderson, Benjamin M.

    2016-09-01

    Projections of future climate change play a fundamental role in improving understanding of the climate system as well as characterizing societal risks and response options. The Scenario Model Intercomparison Project (ScenarioMIP) is the primary activity within Phase 6 of the Coupled Model Intercomparison Project (CMIP6) that will provide multi-model climate projections based on alternative scenarios of future emissions and land use changes produced with integrated assessment models. In this paper, we describe ScenarioMIP's objectives, experimental design, and its relation to other activities within CMIP6. The ScenarioMIP design is one component of a larger scenario process that aims to facilitate a wide range of integrated studies across the climate science, integrated assessment modeling, and impacts, adaptation, and vulnerability communities, and will form an important part of the evidence base in the forthcoming Intergovernmental Panel on Climate Change (IPCC) assessments. At the same time, it will provide the basis for investigating a number of targeted science and policy questions that are especially relevant to scenario-based analysis, including the role of specific forcings such as land use and aerosols, the effect of a peak and decline in forcing, the consequences of scenarios that limit warming to below 2 °C, the relative contributions to uncertainty from scenarios, climate models, and internal variability, and long-term climate system outcomes beyond the 21st century. To serve this wide range of scientific communities and address these questions, a design has been identified consisting of eight alternative 21st century scenarios plus one large initial condition ensemble and a set of long-term extensions, divided into two tiers defined by relative priority. Some of these scenarios will also provide a basis for variants planned to be run in other CMIP6-Endorsed MIPs to investigate questions related to specific forcings. Harmonized, spatially explicit

  20. 5-HT1A/1B, 5-HT6, and 5-HT7 serotonergic receptors recruitment in tonic-clonic seizure-induced antinociception: role of dorsal raphe nucleus.

    PubMed

    Freitas, Renato Leonardo; Ferreira, Célio Marcos dos Reis; Urbina, Maria Angélica Castiblanco; Mariño, Andrés Uribe; Carvalho, Andressa Daiane; Butera, Giuseppe; de Oliveira, Ana Maria; Coimbra, Norberto Cysne

    2009-05-01

    Pharmacological studies have been focused on the involvement of different neural pathways in the organization of antinociception that follows tonic-clonic seizures, including 5-hydroxytryptamine (5-HT)-, norepinephrine-, acetylcholine- and endogenous opioid peptide-mediated mechanisms, giving rise to more in-depth comprehension of this interesting post-ictal antinociceptive phenomenon. The present work investigated the involvement of 5-HT(1A/1B), 5-HT(6), and 5-HT(7) serotonergic receptors through peripheral pretreatment with methiothepin at doses of 0.5, 1.0, 2.0 and 3.0 mg/kg in the organization of the post-ictal antinociception elicited by pharmacologically (with pentylenetetrazole at 64 mg/kg)-induced tonic-clonic seizures. Methiothepin at 1.0 mg/kg blocked the post-ictal antinociception recorded after the end of seizures, whereas doses of 2.0 and 3.0 mg/kg potentiated the post-ictal antinociception. The nociceptive thresholds were kept higher than those of the control group. However, when the same 5-hydroxytryptamine receptors antagonist was microinjected (at 1.0, 3.0 and 5.0 microg/0.2 microL) in the dorsal raphe nucleus, a mesencephalic structure rich in serotonergic neurons and 5-HT receptors, the post-ictal hypo-analgesia was consistently antagonized. The present findings suggest a dual effect of methiothepin, characterized by a disinhibitory effect on the post-ictal antinociception when peripherally administered (possibly due to an antagonism of pre-synaptic 5-HT(1A) serotonergic autoreceptors in the pain endogenous inhibitory system) and an inhibitory effect (possibly due to a DRN post-synaptic 5-HT(1B), 5-HT(6), and 5-HT(7) serotonergic receptors blockade) when centrally administered. The present data also suggest that serotonin-mediated mechanisms of the dorsal raphe nucleus exert a key-role in the modulation of the post-ictal antinociception.

  1. Development and validation of ultra-high-performance liquid chromatography-tandem mass spectrometry methods for the simultaneous determination of beauvericin, enniatins (A, A1, B, B1) and cereulide in maize, wheat, pasta and rice.

    PubMed

    Decleer, Marlies; Rajkovic, Andreja; Sas, Benedikt; Madder, Annemieke; De Saeger, Sarah

    2016-11-11

    Rapid and accurate UPLC-MS/MS methods for the simultaneous determination of beauvericin and the related enniatins (A, A1, B, B1), together with cereulide were successfully developed and validated in cereal and cereal-based food matrices such as wheat, maize, rice and pasta. Although these emerging foodborne toxins are of different microbial origin, the similar structural, toxicological and food safety features provided rationale for their concurrent detection in relevant food matrices. A Waters Acquity UPLC system coupled to a Waters Quattro Premier XE™ Mass Spectrometer operating in ESI+ mode was employed. Sample pretreatment involved a fast and simple liquid extraction of the target toxins without any further clean-up step. For all toxins the sample preparation resulted in acceptable extraction recoveries with values of 85-105% for wheat, 87-106% for maize, 84-106% for rice and 85-105% for pasta. The efficient extraction protocol, together with a fast chromatographic separation of 7min allowed substantial saving costs and time showing its robustness and performance. The validation of the developed method was performed based on Commission Decision 2002/657/EC. The obtained limits of detection ranged from 0.1 to 1.0μgkg(-1) and the limits of quantification from 0.3 to 2.9μgkg(-1) for the targeted toxins in the selected matrices. The obtained sensitivities allow detection of relevant toxicological concentrations. All relative standard deviations for repeatability (intra-day) and intermediate precision (inter-day) were lower than 20%. Trueness, expressed as the apparent recovery varied from 80 to 107%. The highly sensitive and repeatable validated method was applied to 57 naturally contaminated samples allowing detection of sub-clinical doses of the toxins. Copyright © 2016 Elsevier B.V. All rights reserved.

  2. Research on Digitized Scenario for Tactical Internet Simulative Training

    NASA Astrophysics Data System (ADS)

    Shen, Jian-Jun; Tian, Hua; Gan, Zhi-Chun

    The scenario of Tactical Internet simulative training can't be realized directly through the scenario systems and methods in existence. For solving this problem, firstly this paper introduced the new concept called digitized scenario, which can describe the meaning of scenario more exactly than the old simulation scenario. Secondly, this paper constructed the framework of digitized scenario, and it settled such issues as composition of digitized scenario system, scenario generating flow and data architecture. Thirdly, this paper built up the general data model for script situation, and it settled the problem of situation setting. Finally, this paper proposed the method of describing scenario files based on eXtensible Markup Language (XML), and it settled such problems as generation, verification and distribution of scenario files. The paper's work has been applied in the Tactical Internet simulative training system, and it also has good directive value to the developing of other communication network simulative training system.

  3. River multimodal scenario for rehabilitation robotics.

    PubMed

    Munih, Marko; Novak, Domen; Milavec, Maja; Ziherl, Jaka; Olenšek, Andrej; Mihelj, Matjaž

    2011-01-01

    This paper presents the novel "River" multimodal rehabilitation robotics scenario that includes video, audio and haptic modalities. Elements contributing to intrinsic motivation are carefully joined in the three modalities to increase motivation of the user. The user first needs to perform a motor action, then receives a cognitive challenge that is solved with adequate motor activity. Audio includes environmental sounds, music and spoken instructions or encouraging statements. Sounds and music were classified according to the arousal-valence space. The haptic modality can provide catching, grasping, tunnel or adaptive assistance, all depending on the user's needs. The scenario was evaluated in 16 stroke users, who responded to it favourably according to the Intrinsic Motivation Inventory questionnaire. Additionally, the river multimodal environment seems to elicit higher motivation than a simpler apple pick-and-place multimodal task. © 2011 IEEE

  4. Thermodynamical interpretation of gravity in braneworld scenarios

    SciTech Connect

    Sheykhi, Ahmad

    2009-05-15

    We study the thermodynamical properties of the apparent horizon in the various braneworld scenarios. First, we show that the Friedmann equations can be written directly in the form of the first law of thermodynamics, dE = T{sub h}dS{sub h}+WdV, at apparent horizon on the brane, regardless of whether there is the intrinsic curvature term on the brane or a Gauss-Bonnet term in the bulk. This procedure leads to extract an entropy expression in terms of horizon geometry associated with the apparent horizon. Then, we examine the time evolution of the total entropy, including the derived entropy of the apparent horizon and the entropy of the matter fields inside the apparent horizon. We find that the derived entropy of the apparent horizon on the brane satisfies the generalized second law of thermodynamics in braneworld scenarios. These results further support the idea that gravitation on a macroscopic scale is a manifestation of thermodynamics.

  5. The hexagon hypothesis: Six disruptive scenarios.

    PubMed

    Burtles, Jim

    2015-01-01

    This paper aims to bring a simple but effective and comprehensive approach to the development, delivery and monitoring of business continuity solutions. To ensure that the arguments and principles apply across the board, the paper sticks to basic underlying concepts rather than sophisticated interpretations. First, the paper explores what exactly people are defending themselves against. Secondly, the paper looks at how defences should be set up. Disruptive events tend to unfold in phases, each of which invites a particular style of protection, ranging from risk management through to business continuity to insurance cover. Their impact upon any business operation will fall into one of six basic scenarios. The hexagon hypothesis suggests that everyone should be prepared to deal with each of these six disruptive scenarios and it provides them with a useful benchmark for business continuity.

  6. Effective scenario of loop quantum cosmology.

    PubMed

    Ding, You; Ma, Yongge; Yang, Jinsong

    2009-02-06

    Semiclassical states in isotropic loop quantum cosmology are employed to show that the improved dynamics has the correct classical limit. The effective Hamiltonian for the quantum cosmological model with a massless scalar field is thus obtained, which incorporates also the next to leading order quantum corrections. The possibility that the higher order correction terms may lead to significant departure from the leading order effective scenario is revealed. If the semiclassicality of the model is maintained in the large scale limit, there are great possibilities for a k=0 Friedmann expanding universe to undergo a collapse in the future due to the quantum gravity effect. Thus the quantum bounce and collapse may contribute a cyclic universe in the new scenario.

  7. Occupational health scenario of Indian informal sector

    PubMed Central

    NAG, Anjali; VYAS, Heer; NAG, Pranab

    2016-01-01

    Workers in the Indian informal sector are engaged with different occupations. These occupations involve varied work related hazards. These occupational hazards are a consequent risk to health. The study aimed to determine occupational health scenario in the Indian Informal sector. One thousand eleven hundred twenty two workers from five different occupations namely weaving (handloom and power loom), construction, transportation, tobacco processing and fish processing were assessed by interviewer administered health questionnaire. Workers suffered from musculo-skeletal complaints, respiratory health hazards, eye problems and skin related complaints. There was a high prevalence of self-reported occupational health problems in the selected sectors. The study finds that workers have occupational exposures to multiple hazards. The absence of protective guards aggrevate their health condition. The study attempts to draws an immediate attention on the existing health scenario of the Indian Informal sector. PMID:26903262

  8. Selecting reasonable future land use scenarios

    SciTech Connect

    Allred, W.E.; Smith, R.W.

    1995-12-31

    This paper examines a process to help select the most reasonable future land use scenarios for hazardous waste and/or low-level radioactive waste disposal sites. The process involves evaluating future land use scenarios by applying selected criteria currently used by commercial mortgage companies to determine the feasibility of obtaining a loan for purchasing such land. The basis for the process is that only land use activities for which a loan can be obtained will be considered. To examine the process, a low-level radioactive waste site, the Radioactive Waste Management Complex at the Idaho National Engineering Laboratory, is used as an example. The authors suggest that the process is a very precise, comprehensive, and systematic (common sense) approach for determining reasonable future use of land. Implementing such a process will help enhance the planning, decisionmaking, safe management, and cleanup of present and future disposal facilities.

  9. NOAA Regional Sea Level Trends and Scenarios

    NASA Astrophysics Data System (ADS)

    Sweet, W.; Zervas, C.; Leuliette, E. W.

    2016-12-01

    NOAA has a new website to help coastal communities recognize past changes in regional sea level to better plan for a range of possible rise scenarios this century. The site compares 11 regionalized and coherent tide-gauge and satellite-altimeter sea level series from around the U.S. to estimate multi-decadal changes that have occurred in response to regional sea surface height-related trends and variability. Local relative trends are obtainable even without data from a local tide gauge when combined with estimates of vertical land motion, which can be obtained from several years of record from a GPS-based continuously operating reference system (CORS). The regionalized series will be updated annually and displayed relative to the most recent sea level rise scenarios of the (i.e., 2014) National Climate Assessment to characterize the regional sea level change trajectory for future planning of associated impacts.

  10. Selecting reasonable future land use scenarios

    SciTech Connect

    Allred, W.E.; Smith, R.W.

    1995-12-31

    This paper examines a process to help select the most reasonable future land use scenario for hazardous waste and/or low-level radioactive waste disposal sites. The process involves evaluating future land use scenarios ab applying selected criteria currently used by commercial mortgage companies to determine the feasibility of obtaining a loan for purchasing such land. The basis for the process is that only land use activities for which a loan can be obtained well be considered. To examine the process, a low-level radioactive waste site, the Radioactive Waste Management Complex at the Idaho National Engineering Laboratory, is used as an example. The authors suggest that the process is a very precise, comprehensive, and systematic approach for determining reasonable future use of land. Implementing such a process will help enhance the planning, decisionmaking, safe management, and cleanup of present and future disposal facilities.

  11. A new scenario framework for Climate Change Research: Scenario matrix architecture

    SciTech Connect

    Van Vuuren, Detlef; Kriegler, Elmar; O'Neill, Brian; Ebi, Kristie L.; Riahi, Keywan; Carter, Tim; Edmonds, James A.; Hallegatte, Stephane; Kram, Tom; Mathur, Ritu; Winkler, Harald

    2014-02-01

    In this paper, we present the scenario matrix architecture as part of the new scenario framework for climate change research. The matrix architecture focuses on a key question of current climate research, namely the identification of trade-offs and synergies (in terms of risks, costs and other consequences) of different adaptation and mitigation strategies. The framework has two main axes: 1) the level of forcing (as represented by the RCPs) and 2) different socio-economic reference pathways. The matrix can be used as a tool to guide new scenario development and analytical analysis. It can also be used as a heuristic tool for classifying new and existing scenarios for assessment. Key elements of the architecture, in particular the shared socio-economic reference pathways and the shared policy assumptions, are elaborated in other papers in this special issue.

  12. Land-Use Scenarios: National-Scale Housing-Density Scenarios Consistent with Climate Change Storylines (Final Report)

    EPA Science Inventory

    EPA announced the availability of the final report, Land-Use Scenarios: National-Scale Housing-Density Scenarios Consistent with Climate Change Storylines. This report describes the scenarios and models used to generate national-scale housing density scenarios for the con...

  13. Land-Use Scenarios: National-Scale Housing-Density Scenarios Consistent with Climate Change Storylines (Final Report)

    EPA Science Inventory

    EPA announced the availability of the final report, Land-Use Scenarios: National-Scale Housing-Density Scenarios Consistent with Climate Change Storylines. This report describes the scenarios and models used to generate national-scale housing density scenarios for the con...

  14. New procedure of generation of action scenarios

    NASA Astrophysics Data System (ADS)

    Staniszewski, Michał; Wereszczyński, Kamil; Michalczuk, Agnieszka; Fernes, Daniel; Segen, Jakub; Kulbacki, Marek; Wojciechowski, Konrad

    2017-07-01

    Algorithms of tracking and action recognition are still under development and many problems still have to be solved. New methods are usually tested on available benchmarks with defined actions and human behavior however such approach has many limitations. For that reason the authors proposed new procedure of generating random action instances using on graph-based scenarios. Such idea can be applied in creation of different datasets as well as in simulations.

  15. Electroweak Gauge-Higgs Unification Scenario

    SciTech Connect

    Hosotani, Yutaka

    2008-11-23

    In the gauge-Higgs unification scenario 4D Higgs fields are unified with gauge fields in higher dimensions. The electroweak model is constructed in the Randall-Sundrum warped space. The electroweak symmetry is dynamically broken by the Hosotani mechanism due to the top quark contribution. The Higgs mass is predicted to be around 50 GeV with the vanishing ZZH and WWH couplings so that the LEP2 bound for the Higgs mass is evaded.

  16. Arctic shipping emissions inventories and future scenarios

    NASA Astrophysics Data System (ADS)

    Corbett, J. J.; Lack, D. A.; Winebrake, J. J.; Harder, S.; Silberman, J. A.; Gold, M.

    2010-04-01

    The Arctic is a sensitive region in terms of climate change and a rich natural resource for global economic activity. Arctic shipping is an important contributor to the region's anthropogenic air emissions, including black carbon - a short-lived climate forcing pollutant especially effective in accelerating the melting of ice and snow. These emissions are projected to increase as declining sea ice coverage due to climate change allows for increased shipping activity in the Arctic. To understand the impacts of these increased emissions, scientists and modelers require high-resolution, geospatial emissions inventories that can be used for regional assessment modeling. This paper presents 5 km×5 km Arctic emissions inventories of important greenhouse gases, black carbon and other pollutants under existing and future (2050) scenarios that account for growth of shipping in the region, potential diversion traffic through emerging routes, and possible emissions control measures. Short-lived forcing of ~4.5 gigagrams of black carbon from Arctic shipping may increase climate forcing; a first-order calculation of global warming potential due to 2030 emissions in the high-growth scenario suggests that short-lived forcing of ~4.5 gigagrams of black carbon from Arctic shipping may increase climate forcing due to Arctic ships by at least 17% compared to warming from these vessels' CO2 emissions (~42 000 gigagrams). The paper also presents maximum feasible reduction scenarios for black carbon in particular. These emissions reduction scenarios will enable scientists and policymakers to evaluate the efficacy and benefits of technological controls for black carbon, and other pollutants from ships.

  17. CORSICA modelling of ITER hybrid operation scenarios

    NASA Astrophysics Data System (ADS)

    Kim, S. H.; Bulmer, R. H.; Campbell, D. J.; Casper, T. A.; LoDestro, L. L.; Meyer, W. H.; Pearlstein, L. D.; Snipes, J. A.

    2016-12-01

    The hybrid operating mode observed in several tokamaks is characterized by further enhancement over the high plasma confinement (H-mode) associated with reduced magneto-hydro-dynamic (MHD) instabilities linked to a stationary flat safety factor (q ) profile in the core region. The proposed ITER hybrid operation is currently aiming at operating for a long burn duration (>1000 s) with a moderate fusion power multiplication factor, Q , of at least 5. This paper presents candidate ITER hybrid operation scenarios developed using a free-boundary transport modelling code, CORSICA, taking all relevant physics and engineering constraints into account. The ITER hybrid operation scenarios have been developed by tailoring the 15 MA baseline ITER inductive H-mode scenario. Accessible operation conditions for ITER hybrid operation and achievable range of plasma parameters have been investigated considering uncertainties on the plasma confinement and transport. ITER operation capability for avoiding the poloidal field coil current, field and force limits has been examined by applying different current ramp rates, flat-top plasma currents and densities, and pre-magnetization of the poloidal field coils. Various combinations of heating and current drive (H&CD) schemes have been applied to study several physics issues, such as the plasma current density profile tailoring, enhancement of the plasma energy confinement and fusion power generation. A parameterized edge pedestal model based on EPED1 added to the CORSICA code has been applied to hybrid operation scenarios. Finally, fully self-consistent free-boundary transport simulations have been performed to provide information on the poloidal field coil voltage demands and to study the controllability with the ITER controllers. Extended from Proc. 24th Int. Conf. on Fusion Energy (San Diego, 2012) IT/P1-13.

  18. A Visual Language for Composable Simulation Scenarios

    DTIC Science & Technology

    2003-03-01

    engineering and simulation was conducted. An evaluation of the benefits and limitations of the behavior specification methods when applied to the...that have been applied to software engineering and simulations in the past. 32 2.8.1 Object-Oriented Software Behavior Specification Methods and...scenarios. There are several behavior specification techniques used in software engineering and modeling and simulation. These methods included process

  19. Commercial Mobile Alert Service (CMAS) Scenarios

    DTIC Science & Technology

    2012-05-01

    www.3csoftware.com/blog/the-five-ws-and-one-h-of- designing -systems (2011). [Bass 2003] Bass, L.; Clements, P. C.; & Kazman, R. Software Architecture...Evaluate Architectural Design Approaches in a Major System Acquisition: A Case Study (CMU/SEI-2000-TN-010). Software Engineering Institute, Carnegie...Commercial Mobile Alert Service (CMAS) Scenarios The WEA Project Team May 2012 SPECIAL REPORT CMU/SEI-2012-SR-020 CERT® Division, Software

  20. A tilted cold dark matter cosmological scenario

    NASA Technical Reports Server (NTRS)

    Cen, Renyue; Gnedin, Nickolay Y.; Kofman, Lev A.; Ostriker, Jeremiah P.

    1992-01-01

    A new cosmological scenario based on CDM but with a power spectrum index of about 0.7-0.8 is suggested. This model is predicted by various inflationary models with no fine tuning. This tilted CDM model, if normalized to COBE, alleviates many problems of the standard CDM model related to both small-scale and large-scale power. A physical bias of galaxies over dark matter of about two is required to fit spatial observations.

  1. Necrotizing Fasciitis: An Emergency Medicine Simulation Scenario

    PubMed Central

    Galust, Henrik; Oliverio, Matthew H; Giorgio, Daniel J; Espinal, Alexis M

    2016-01-01

    Necrotizing fasciitis (NF) is a rare and rapidly progressing life-threatening infectious process. By progressing through a simulation involving a patient with NF and participating in a post-scenario debriefing, learners will gain the necessary skills and knowledge to properly diagnose and manage patients with NF. Learners are taught to initiate appropriate and timely treatment and to advocate on behalf of their patient after inappropriate pushback from consultants to improve outcomes. PMID:27733963

  2. Moving beyond ice loss scenarios for Antarctica

    NASA Astrophysics Data System (ADS)

    Little, C. M.; Oppenheimer, M.; Urban, N.

    2010-12-01

    Scenario-based projections of individual components of sea level change are difficult to reconcile with probability distributions for sea level at the global and/or local scale. It is also difficult to assess the origin of key subjective decisions in the construction of these scenarios. An example is the historical distinction between the sensitivity of the East and West Antarctic Ice Sheets to climatic forcing. Observations show that this distinction may not have a well-defined physical basis at smaller scales. Recent “kinematic” approaches impose increases in ice discharge at the scale of individual outlet glaciers, yet the criteria for inclusion in these scenarios are unclear and differ between studies. Projections of the response of sub-regions of ice sheets to climate forcing should be informed by key physical characteristics, which may include ocean and/or atmospheric boundary conditions, bedrock and embayment morphology, and the stress regime of the grounded ice. Here, we assess: 1) the volume of Antarctic ice that is included in ice loss scenarios under different plausible sets of assumptions, and 2) the impact of these assumptions on the Antarctic contribution to sea level change. In the short term, this approach may raise or lower upper bounds proposed by earlier studies, depending on the criteria and rates employed. Perhaps more importantly, it is a step towards a fully probabilistic methodology, informing the requirements for models that may be used in probabilistic projections. Updating is possible: key sources of uncertainty may be revisited as more is learned about future climate forcing and rate-limiting processes in ice sheets.

  3. Quintom scenario with mixed kinetic terms

    SciTech Connect

    Saridakis, Emmanuel N.; Weller, Joel M.

    2010-06-15

    We examine an extension of the quintom scenario of dark energy, in which a canonical scalar field and a phantom field are coupled through a kinetic interaction. We perform a phase-space analysis and show that the kinetic coupling gives rise to novel cosmological behavior. In particular, we obtain both quintessence-like and phantomlike late-time solutions, as well as solutions that cross the phantom divide during the evolution of the Universe.

  4. Motivating an intergenerational workforce: scenarios for success.

    PubMed

    Wieck, K Lynn

    2007-01-01

    Although much has been written about the challenge of having four generations in the workplace simultaneously, problems of conflict, misunderstanding, and divisiveness continue. This article provides a snapshot of each generation as context. A series of scenarios based on Maslow's Hierarchy of Needs are then presented with insights into how each generation might approach the situation, along with hints for successfully managing toward positive outcomes. The expected outcome is a technique for each generation to look at workplace situations from all perspectives.

  5. Glacial CO2 Cycles: A Composite Scenario

    NASA Astrophysics Data System (ADS)

    Broecker, W. S.

    2015-12-01

    There are three main contributors to the glacial drawdown of atmospheric CO2 content: starvation of the supply of carbon to the ocean-atmosphere reservoir, excess CO2 storage in the deep sea, and surface-ocean cooling. In this talk, I explore a scenario in which all three play significant roles. Key to this scenario is the assumption that deep ocean storage is related to the extent of nutrient stratification of the deep Atlantic. The stronger this stratification, the larger the storage of respiration CO2. Further, it is my contention that the link between Milankovitch insolation cycles and climate is reorganizations of the ocean's thermohaline circulation leading to changes in the deep ocean's CO2 storage. If this is the case, the deep Atlantic d13C record kept in benthic foraminifera shells tells us that deep ocean CO2 storage follows Northern Hemisphere summer insolation cycles and thus lacks the downward ramp so prominent in the records of sea level, benthic 18O and CO2. Rather, the ramp is created by the damping of planetary CO2 emissions during glacial time intervals. As it is premature to present a specific scenario, I provide an example as to how these three contributors might be combined. As their magnitudes and shapes remain largely unconstrained, the intent of this exercise is to provoke creative thinking.

  6. CP violation in heavy MSSM Higgs scenarios

    SciTech Connect

    Carena, M.; Ellis, J.; Lee, J. S.; Pilaftsis, A.; Wagner, C. E. M.

    2016-02-18

    We introduce and explore new heavy Higgs scenarios in the Minimal Supersymmetric Standard Model (MSSM) with explicit CP violation, which have important phenomenological implications that may be testable at the LHC. For soft supersymmetry-breaking scales MS above a few TeV and a charged Higgs boson mass MH+ above a few hundred GeV, new physics effects including those from explicit CP violation decouple from the light Higgs boson sector. However, such effects can significantly alter the phenomenology of the heavy Higgs bosons while still being consistent with constraints from low-energy observables, for instance electric dipole moments. To consider scenarios with a charged Higgs boson much heavier than the Standard Model (SM) particles but much lighter than the supersymmetric particles, we revisit previous calculations of the MSSM Higgs sector. We compute the Higgs boson masses in the presence of CP violating phases, implementing improved matching and renormalization-group (RG) effects, as well as two-loop RG effects from the effective two-Higgs Doublet Model (2HDM) scale MH± to the scale MS. Here, we illustrate the possibility of non-decoupling CP-violating effects in the heavy Higgs sector using new benchmark scenarios named.

  7. CP violation in heavy MSSM Higgs scenarios

    DOE PAGES

    Carena, M.; Ellis, J.; Lee, J. S.; ...

    2016-02-18

    We introduce and explore new heavy Higgs scenarios in the Minimal Supersymmetric Standard Model (MSSM) with explicit CP violation, which have important phenomenological implications that may be testable at the LHC. For soft supersymmetry-breaking scales MS above a few TeV and a charged Higgs boson mass MH+ above a few hundred GeV, new physics effects including those from explicit CP violation decouple from the light Higgs boson sector. However, such effects can significantly alter the phenomenology of the heavy Higgs bosons while still being consistent with constraints from low-energy observables, for instance electric dipole moments. To consider scenarios with amore » charged Higgs boson much heavier than the Standard Model (SM) particles but much lighter than the supersymmetric particles, we revisit previous calculations of the MSSM Higgs sector. We compute the Higgs boson masses in the presence of CP violating phases, implementing improved matching and renormalization-group (RG) effects, as well as two-loop RG effects from the effective two-Higgs Doublet Model (2HDM) scale MH± to the scale MS. Here, we illustrate the possibility of non-decoupling CP-violating effects in the heavy Higgs sector using new benchmark scenarios named.« less

  8. Deforestation scenarios for the Bolivian lowlands.

    PubMed

    Tejada, Graciela; Dalla-Nora, Eloi; Cordoba, Diana; Lafortezza, Raffaele; Ovando, Alex; Assis, Talita; Aguiar, Ana Paula

    2016-01-01

    Tropical forests in South America play a key role in the provision of ecosystem services such as carbon sinks, biodiversity conservation, and global climate regulation. In previous decades, Bolivian forests have mainly been deforested by the expansion of agricultural frontier development, driven by the growing demands for beef and other productions. In the mid-2000s the Movimiento al Socialismo (MAS) party rose to power in Bolivia with the promise of promoting an alternative development model that would respect the environment. The party passed the world's first laws granting rights to the environment, which they termed Mother Earth (Law No. 300 of 2012), and proposed an innovative framework that was expected to develop radical new conservation policies. The MAS conservationist discourse, policies, and productive practices, however, have since been in permanent tension. The government continues to guarantee food production through neo-extractivist methods by promoting the notion to expand agriculture from 3 to 13 million ha, risking the tropical forests and their ecosystem services. These actions raise major environmental and social concerns, as the potential impacts of such interventions are still unknown. The objective of this study is to explore an innovative land use modeling approach to simulate how the growing demand for land could affect future deforestation trends in Bolivia. We use the LuccME framework to create a spatially-explicit land cover change model and run it under three different deforestation scenarios, spanning from the present-2050. In the Sustainability scenario, deforestation reaches 17,703,786 ha, notably in previously deforested or degraded areas, while leaving forest extensions intact. In the Middle of the road scenario, deforestation and degradation move toward new or paved roads spreading across 25,698,327 ha in 2050, while intact forests are located in Protected Areas (PAs). In the Fragmentation scenario, deforestation expands to almost

  9. The HayWired earthquake scenario

    USGS Publications Warehouse

    Detweiler, Shane T.; Wein, Anne M.

    2017-04-24

    ForewordThe 1906 Great San Francisco earthquake (magnitude 7.8) and the 1989 Loma Prieta earthquake (magnitude 6.9) each motivated residents of the San Francisco Bay region to build countermeasures to earthquakes into the fabric of the region. Since Loma Prieta, bay-region communities, governments, and utilities have invested tens of billions of dollars in seismic upgrades and retrofits and replacements of older buildings and infrastructure. Innovation and state-of-the-art engineering, informed by science, including novel seismic-hazard assessments, have been applied to the challenge of increasing seismic resilience throughout the bay region. However, as long as people live and work in seismically vulnerable buildings or rely on seismically vulnerable transportation and utilities, more work remains to be done.With that in mind, the U.S. Geological Survey (USGS) and its partners developed the HayWired scenario as a tool to enable further actions that can change the outcome when the next major earthquake strikes. By illuminating the likely impacts to the present-day built environment, well-constructed scenarios can and have spurred officials and citizens to take steps that change the outcomes the scenario describes, whether used to guide more realistic response and recovery exercises or to launch mitigation measures that will reduce future risk.The HayWired scenario is the latest in a series of like-minded efforts to bring a special focus onto the impacts that could occur when the Hayward Fault again ruptures through the east side of the San Francisco Bay region as it last did in 1868. Cities in the east bay along the Richmond, Oakland, and Fremont corridor would be hit hardest by earthquake ground shaking, surface fault rupture, aftershocks, and fault afterslip, but the impacts would reach throughout the bay region and far beyond. The HayWired scenario name reflects our increased reliance on the Internet and telecommunications and also alludes to the

  10. Public Review Draft: A Method for Assessing Carbon Stocks, Carbon Sequestration, and Greenhouse-Gas Fluxes in Ecosystems of the United States Under Present Conditions and Future Scenarios

    USGS Publications Warehouse

    Bergamaschi, Brian A.; Bernknopf, Richard; Clow, David; Dye, Dennis; Faulkner, Stephen; Forney, William; Gleason, Robert; Hawbaker, Todd; Liu, Jinxun; Liu, Shu-Guang; Prisley, Stephen; Reed, Bradley; Reeves, Matthew; Rollins, Matthew; Sleeter, Benjamin; Sohl, Terry; Stackpoole, Sarah; Stehman, Stephen; Striegl, Robert G.; Wein, Anne; Zhu, Zhi-Liang; Zhu, Zhi-Liang

    2010-01-01

    The Energy Independence and Security Act of 2007 (EISA), Section 712, authorizes the U.S. Department of the Interior to develop a methodology and conduct an assessment of the Nation's ecosystems focusing on carbon stocks, carbon sequestration, and emissions of three greenhouse gases (GHGs): carbon dioxide, methane, and nitrous oxide. The major requirements include (1) an assessment of all ecosystems (terrestrial systems, such as forests, croplands, wetlands, shrub and grasslands; and aquatic ecosystems, such as rivers, lakes, and estuaries), (2) an estimation of annual potential capacities of ecosystems to increase carbon sequestration and reduce net GHG emissions in the context of mitigation strategies (including management and restoration activities), and (3) an evaluation of the effects of controlling processes, such as climate change, land use and land cover, and wildlfires. The purpose of this draft methodology for public review is to propose a technical plan to conduct the assessment. Within the methodology, the concepts of ecosystems, carbon pools, and GHG fluxes used for the assessment follow conventional definitions in use by major national and international assessment or inventory efforts. In order to estimate current ecosystem carbon stocks and GHG fluxes and to understand the potential capacity and effects of mitigation strategies, the method will use two time periods for the assessment: 2001 through 2010, which establishes a current ecosystem GHG baseline and will be used to validate the models; and 2011 through 2050, which will be used to assess future potential conditions based on a set of projected scenarios. The scenario framework is constructed using storylines of the Intergovernmental Panel on Climate Change (IPCC) Special Report Emission Scenarios (SRES), along with initial reference land-use and land-cover (LULC) and land-management scenarios. An additional three LULC and land-management mitigation scenarios will be constructed for each

  11. The Extent to Which Different 100% Clean, Renewable Energy Transition Scenarios can Reduce World Carbon Dioxide Levels to 350-400 ppmv by 2100

    NASA Astrophysics Data System (ADS)

    Jacobson, M. Z.; Byrne, J. M.

    2016-12-01

    Future levels of atmospheric carbon dioxide (CO2) depend on CO2's natural and anthropogenic emission rates and its removal rates by primarily water dissolution, photosysnthesis, and weathering. We compare modeled past CO2 from 1750 to 2015 with data then model projected future changes in CO2 under different energy emission scenarios, including two where 100% of the world's all-purpose energy (electricity, transportation, heating/cooling, industry, and agriculture/forestry/fishing) is electrified, and the electricity is powered by wind, water, and sunlight (WWS). The scenarios are derived from country-by-country energy roadmaps found at http://web.stanford.edu/group/efmh/jacobson/Articles/I/WWS-50-USState-plans.html. In one 100% scenario, 80% of the conversion is assumed to occur by 2030 and 100%, by 2050. In the second, 80% is assumed to occur by 2050, and the rest by 2100. We also compare with an unrealistic but best-case 100% conversion scenario starting in 2015 and IPCC scenarios A1B, A2, B1, B2, and A1F1. Results will be shown, and conclusions, drawn about the practicality of reducing CO2 to 350-400 ppmv by 2100. These results have significant impact on current and future energy policy.

  12. Underground infrastructure damage for a Chicago scenario

    SciTech Connect

    Dey, Thomas N; Bos, Rabdall J

    2011-01-25

    Estimating effects due to an urban IND (improvised nuclear device) on underground structures and underground utilities is a challenging task. Nuclear effects tests performed at the Nevada Test Site (NTS) during the era of nuclear weapons testing provides much information on how underground military structures respond. Transferring this knowledge to answer questions about the urban civilian environment is needed to help plan responses to IND scenarios. Explosions just above the ground surface can only couple a small fraction of the blast energy into an underground shock. The various forms of nuclear radiation have limited penetration into the ground. While the shock transmitted into the ground carries only a small fraction of the blast energy, peak stresses are generally higher and peak ground displacement is lower than in the air blast. While underground military structures are often designed to resist stresses substantially higher than due to the overlying rocks and soils (overburden), civilian structures such as subways and tunnels would generally only need to resist overburden conditions with a suitable safety factor. Just as we expect the buildings themselves to channel and shield air blast above ground, basements and other underground openings as well as changes of geology will channel and shield the underground shock wave. While a weaker shock is expected in an urban environment, small displacements on very close-by faults, and more likely, soils being displaced past building foundations where utility lines enter could readily damaged or disable these services. Immediately near an explosion, the blast can 'liquefy' a saturated soil creating a quicksand-like condition for a period of time. We extrapolate the nuclear effects experience to a Chicago-based scenario. We consider the TARP (Tunnel and Reservoir Project) and subway system and the underground lifeline (electric, gas, water, etc) system and provide guidance for planning this scenario.

  13. Inventories and scenarios of nitrous oxide emissions

    NASA Astrophysics Data System (ADS)

    Davidson, Eric A.; Kanter, David

    2014-10-01

    Effective mitigation for N2O emissions, now the third most important anthropogenic greenhouse gas and the largest remaining anthropogenic source of stratospheric ozone depleting substances, requires understanding of the sources and how they may increase this century. Here we update estimates and their uncertainties for current anthropogenic and natural N2O emissions and for emissions scenarios to 2050. Although major uncertainties remain, ‘bottom-up’ inventories and ‘top-down’ atmospheric modeling yield estimates that are in broad agreement. Global natural N2O emissions are most likely between 10 and 12 Tg N2O-N yr-1. Net anthropogenic N2O emissions are now about 5.3 Tg N2O-N yr-1. Gross anthropogenic emissions by sector are 66% from agriculture, 15% from energy and transport sectors, 11% from biomass burning, and 8% from other sources. A decrease in natural emissions from tropical soils due to deforestation reduces gross anthropogenic emissions by about 14%. Business-as-usual emission scenarios project almost a doubling of anthropogenic N2O emissions by 2050. In contrast, concerted mitigation scenarios project an average decline of 22% relative to 2005, which would lead to a near stabilization of atmospheric concentration of N2O at about 350 ppb. The impact of growing demand for biofuels on future projections of N2O emissions is highly uncertain; N2O emissions from second and third generation biofuels could remain trivial or could become the most significant source to date. It will not be possible to completely eliminate anthropogenic N2O emissions from agriculture, but better matching of crop N needs and N supply offers significant opportunities for emission reductions.

  14. Riparian vegetation structure under desertification scenarios

    NASA Astrophysics Data System (ADS)

    Rosário Fernandes, M.; Segurado, Pedro; Jauch, Eduardo; Ferreira, M. Teresa

    2015-04-01

    Riparian areas are responsible for many ecological and ecosystems services, including the filtering function, that are considered crucial to the preservation of water quality and social benefits. The main goal of this study is to quantify and understand the riparian variability under desertification scenario(s) and identify the optimal riparian indicators for water scarcity and droughts (WS&D), henceforth improving river basin management. This study was performed in the Iberian Tâmega basin, using riparian woody patches, mapped by visual interpretation on Google Earth imagery, along 130 Sampling Units of 250 m long river stretches. Eight riparian structural indicators, related with lateral dimension, weighted area and shape complexity of riparian patches were calculated using Patch Analyst extension for ArcGis 10. A set of 29 hydrological, climatic, and hydrogeomorphological variables were computed, by a water modelling system (MOHID), using monthly meteorological data between 2008 and 2014. Land-use classes were also calculated, in a 250m-buffer surrounding each sampling unit, using a classification based system on Corine Land Cover. Boosted Regression Trees identified Mean-width (MW) as the optimal riparian indicator for water scarcity and drought, followed by the Weighted Class Area (WCA) (classification accuracy =0.79 and 0.69 respectively). Average Flow and Strahler number were consistently selected, by all boosted models, as the most important explanatory variables. However, a combined effect of hidrogeomorphology and land-use can explain the high variability found in the riparian width mainly in Tâmega tributaries. Riparian patches are larger towards Tâmega river mouth although with lower shape complexity, probably related with more continuous and almost monospecific stands. Climatic, hydrological and land use scenarios, singly and combined, were used to quantify the riparian variability responding to these changes, and to assess the loss of riparian

  15. Management strategies in hospitals: scenario planning

    PubMed Central

    Ghanem, Mohamed; Schnoor, Jörg; Heyde, Christoph-Eckhard; Kuwatsch, Sandra; Bohn, Marco; Josten, Christoph

    2015-01-01

    Background: Instead of waiting for challenges to confront hospital management, doctors and managers should act in advance to optimize and sustain value-based health. This work highlights the importance of scenario planning in hospitals, proposes an elaborated definition of the stakeholders of a hospital and defines the influence factors to which hospitals are exposed to. Methodology: Based on literature analysis as well as on personal interviews with stakeholders we propose an elaborated definition of stakeholders and designed a questionnaire that integrated the following influence factors, which have relevant impact on hospital management: political/legal, economic, social, technological and environmental forces. These influence factors are examined to develop the so-called critical uncertainties. Thorough identification of uncertainties was based on a “Stakeholder Feedback”. Results: Two key uncertainties were identified and considered in this study: the development of workload for the medical staff the profit oriented performance of the medical staff. According to the developed scenarios, complementary education of the medical staff as well as of non-medical top executives and managers of hospitals was the recommended core strategy. Complementary scenario-specific strategic options should be considered whenever needed to optimize dealing with a specific future development of the health care environment. Conclusion: Strategic planning in hospitals is essential to ensure sustainable success. It considers multiple situations and integrates internal and external insights and perspectives in addition to identifying weak signals and “blind spots”. This flows into a sound planning for multiple strategic options. It is a state of the art tool that allows dealing with the increasing challenges facing hospital management. PMID:26504735

  16. R modes and neutron star recycling scenario

    NASA Astrophysics Data System (ADS)

    Chugunov, A. I.; Gusakov, M. E.; Kantor, E. M.

    2017-06-01

    To put new constraints on the r-mode instability window, we analyse the formation of millisecond pulsars (MSPs) within the recycling scenario, making use of three sets of observations: (a) X-ray observations of neutron stars (NSs) in low-mass X-ray binaries; (b) timing of MSPs and (c) X-ray and UV observations of MSPs. As shown in previous works, r-mode dissipation by shear viscosity is not sufficient to explain observational set (a), and enhanced r-mode dissipation at the redshifted internal temperatures T ∞ ˜ 108 K is required to stabilize the observed NSs. Here, we argue that models with enhanced bulk viscosity can hardly lead to a self-consistent explanation of observational set (a) due to strong neutrino emission, which is typical for these models (unrealistically powerful energy source is required to keep NSs at the observed temperatures.). We also demonstrate that the observational set (b), combined with the theory of internal heating and NS cooling, provides evidence of enhanced r-mode dissipation at low temperatures, T ∞ ˜ 2 × 107 K. Observational set (c) allows us to set an upper limit on the internal temperatures of MSPs, T ∞ < 2 × 107 K (assuming a canonical NS with the accreted crust). Recycling scenario can produce MSPs at these temperatures only if r-mode instability is suppressed in the whole MSP spin frequency range (ν ≲ 750 Hz) at temperatures 2 × 107 ≲ T ∞ ≲ 3 × 107 K, providing thus a new constraint on the r-mode instability window. These observational constraints are analysed in more details in application to the resonance uplift scenario of Gusakov et al.

  17. Postulated accident scenarios in weapons disassembly

    SciTech Connect

    Payne, S.S.

    1997-06-01

    A very brief summary of three postulated accident scenarios for weapons disassembly is provided in the paper. The first deals with a tetrahedral configuration of four generic pits; the second, an infinite planar array of generic pits with varying interstitial water density; and the third, a spherical shell with internal mass suspension in water varying the size and mass of the shell. Calculations were performed using the Monte Carlo Neutron Photon transport code MCNP4A. Preliminary calculations pointed to a need for higher resolution of small pit separation regimes and snapshots of hydrodynamic processes of water/plutonium mixtures.

  18. Emergent physics: Fermi-point scenario.

    PubMed

    Volovik, Grigory

    2008-08-28

    The Fermi-point scenario of emergent gravity has the following consequences: gravity emerges together with fermionic and bosonic matter; emergent fermionic matter consists of massless Weyl fermions; emergent bosonic matter consists of gauge fields; Lorentz symmetry persists well above the Planck energy; space-time is naturally four dimensional; the Universe is naturally flat; the cosmological constant is naturally small or zero; the underlying physics is based on discrete symmetries; 'quantum gravity' cannot be obtained by quantization of Einstein equations; and there is no contradiction between quantum mechanics and gravity, etc.

  19. Braneworld Scenarios from Deformed Defect Chains

    NASA Astrophysics Data System (ADS)

    Chinaglia, M.; Bernardini, A. E.; da Rocha, Roldão

    2016-10-01

    Novel braneworld scenarios supported by warp factors driven by a single extra dimension are obtained from deformed one-dimensional lump-like solutions known a priori. Through a novel ansatz, the internal energy structure, the braneworld warp factor, and the quantum mechanical analogue problem, as well as the associated zero mode solutions, are straightforwardly derived by means of an analytical procedure. The results allow one to identify thick brane solutions that support internal structures and that can hold the (3+1)-dimensional gravity.

  20. Automated Scenario Generation and Interaction Techniques

    DTIC Science & Technology

    1981-06-01

    LEVEIt2 RADC-TR4. 1 - 1 1 Phwl Technical Report Jun. 1981 4 ": AUTOMATED SCENARIO GENERATION AND INTERACTION TECHNIQUES Martin Marietto Aerospace...SECURITY CLASSIFICATION OF THIS PAGE (When Date Rnterod) TABLE OF CONTENTS 1.0 INTRODUCTION 1 2.0 OBJECTIVES 2 3.0 APPROACH 2 4.0 INTERVIEW RESULTS 3 5.0...method 4> are: ( 1 ) the ability to analyze a player’s response to a given situation at the time that the situation arises; (2) to allow each player to

  1. Naturalness in testable type II seesaw scenarios

    NASA Astrophysics Data System (ADS)

    Dev, P. S. Bhupal; Vila, Clara Miralles; Rodejohann, Werner

    2017-08-01

    New physics coupling to the Higgs sector of the Standard Model can lead to dangerously large corrections to the Higgs mass. We investigate this problem in the type II seesaw model for neutrino mass, where a weak scalar triplet is introduced. The interplay of direct and indirect constraints on the type II seesaw model with its contribution to the Higgs mass is analyzed. The focus lies on testable triplet masses and (sub) eV-scale triplet vacuum expectation values. We identify scenarios that are testable in collider and/or lepton flavor violation experiments, while satisfying the Higgs naturalness criterion.

  2. 2015 Standard Scenarios Annual Report: U.S. Electric Sector Scenario Exploration

    SciTech Connect

    Sullivan, Patrick; Cole, Wesley; Blair, Nate; Lantz, Eric; Krishnan, Venkat; Mai, Trieu; Mulcahy, David; Porro, Gian

    2015-07-16

    This report is one of several products resulting from an initial effort to provide a consistent set of technology cost and performance data and to define a conceptual and consistent scenario framework that can be used in the National Renewable Energy Laboratory’s (NREL’s) future analyses. The long-term objective of this effort is to identify a range of possible futures of the U.S. electricity sector in which to consider specific energy system issues through (1) defining a set of prospective scenarios that bound ranges of key technology, market, and policy assumptions and (2) assessing these scenarios in NREL’s market models to understand the range of resulting outcomes, including energy technology deployment and production, energy prices, and carbon dioxide (CO2) emissions.

  3. Haunted Quantum Entanglement: A New Scenario

    NASA Astrophysics Data System (ADS)

    Snyder, Douglas

    2010-10-01

    A haunted quantum entanglement scenario is proposed that is very close to Greenberger and YaSin's haunted measurement in that: 1) the entity that is developing as a which-way marker is effectively restored to its state prior to its developing as a which-way marker, and 2) the entity for which the developing which-way marker provides information enters the state it would have had if the development of the which-way marker had never begun. In the hqe scenario, the loss of developing which-way information through 1 relies on the loss of a developing entanglement. The photon initially emitted in one of two micromaser cavities and developing into a which-way marker is effectively lost through the injection of classical microwave radiation into both of the microwave cavities: 1) after the atom initially emits the photon into one of the micromaser cavities and exits the cavity system, and 2) before this atom reaches the 2 slit screen. The atom enters the state it would have had if the atom had never emitted the photon into one of the micromaser cavities because of the injection of classical microwave radiation into both of the microwave cavities and the presence of an rf coil situated at the exit of the micromaser cavity system.

  4. Mars Sample Return mission: Two alternate scenarios

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Two scenarios for accomplishing a Mars Sample Return mission are presented herein. Mission A is a low cost, low mass scenario, while Mission B is a high technology, high science alternative. Mission A begins with the launch of one Titan IV rocket with a Centaur G' upper stage. The Centaur performs the trans-Mars injection burn and is then released. The payload consists of two lander packages and the Orbital Transfer Vehicle, which is responsible for supporting the landers during launch and interplanetary cruise. After descending to the surface, the landers deploy small, local rovers to collect samples. Mission B starts with 4 Titan IV launches, used to place the parts of the Planetary Transfer Vehicle (PTV) into orbit. The fourth launch payload is able to move to assemble the entire vehicle by simple docking routines. Once complete, the PTV begins a low thrust trajectory out from low Earth orbit, through interplanetary space, and into low Martian orbit. It deploys a communication satellite into a 1/2 sol orbit and then releases the lander package at 500 km altitude. The lander package contains the lander, the Mars Ascent Vehicle (MAV), two lighter than air rovers (called Aereons), and one conventional land rover. The entire package is contained with a biconic aeroshell. After release from the PTV, the lander package descends to the surface, where all three rovers are released to collect samples and map the terrain.

  5. Dark Matter searches: the nightmare scenario

    NASA Astrophysics Data System (ADS)

    Bertone, Gianfranco; Cumberbatch, Daniel; Ruiz de Austri, Roberto; Trotta, Roberto

    2012-01-01

    The unfortunate case where the Large Hadron Collider (LHC) fails to discover physics Beyond the Standard Model (BSM) is sometimes referred to as the ``Nightmare scenario'' of particle physics. We study the consequences of this hypothetical scenario for Dark Matter (DM), in the framework of the constrained Minimal Supersymmetric Standard Model (cMSSM). We evaluate the surviving regions of the cMSSM parameter space after null searches at the LHC, using several different LHC configurations, and study the consequences for DM searches with ton-scale direct detectors and the IceCube neutrino telescope. We demonstrate that ton-scale direct detection experiments will be able to conclusively probe the cMSSM parameter space that would survive null searches at the LHC with 100 fb-1 of integrated luminosity at 14 TeV. We also demonstrate that IceCube (80 strings plus DeepCore) will be able to probe as much as simeq 17% of the currently favoured parameter space after 5 years of observation.

  6. Dark Matter searches: the nightmare scenario

    SciTech Connect

    Bertone, Gianfranco; Cumberbatch, Daniel; Austri, Roberto Ruiz de

    2012-01-01

    The unfortunate case where the Large Hadron Collider (LHC) fails to discover physics Beyond the Standard Model (BSM) is sometimes referred to as the ''Nightmare scenario'' of particle physics. We study the consequences of this hypothetical scenario for Dark Matter (DM), in the framework of the constrained Minimal Supersymmetric Standard Model (cMSSM). We evaluate the surviving regions of the cMSSM parameter space after null searches at the LHC, using several different LHC configurations, and study the consequences for DM searches with ton-scale direct detectors and the IceCube neutrino telescope. We demonstrate that ton-scale direct detection experiments will be able to conclusively probe the cMSSM parameter space that would survive null searches at the LHC with 100 fb{sup −1} of integrated luminosity at 14 TeV. We also demonstrate that IceCube (80 strings plus DeepCore) will be able to probe as much as ≅ 17% of the currently favoured parameter space after 5 years of observation.

  7. Biomass Scenario Model Documentation: Data and References

    SciTech Connect

    Lin, Y.; Newes, E.; Bush, B.; Peterson, S.; Stright, D.

    2013-05-01

    The Biomass Scenario Model (BSM) is a system dynamics model that represents the entire biomass-to-biofuels supply chain, from feedstock to fuel use. The BSM is a complex model that has been used for extensive analyses; the model and its results can be better understood if input data used for initialization and calibration are well-characterized. It has been carefully validated and calibrated against the available data, with data gaps filled in using expert opinion and internally consistent assumed values. Most of the main data sources that feed into the model are recognized as baseline values by the industry. This report documents data sources and references in Version 2 of the BSM (BSM2), which only contains the ethanol pathway, although subsequent versions of the BSM contain multiple conversion pathways. The BSM2 contains over 12,000 total input values, with 506 distinct variables. Many of the variables are opportunities for the user to define scenarios, while others are simply used to initialize a stock, such as the initial number of biorefineries. However, around 35% of the distinct variables are defined by external sources, such as models or reports. The focus of this report is to provide insight into which sources are most influential in each area of the supply chain.

  8. Revised scenario for human missions to Mars

    NASA Astrophysics Data System (ADS)

    Salotti, Jean Marc

    2012-12-01

    We present a revised version of our scenario for human missions to Mars. The idea is to take into consideration the difficulties and constraints for entry, descent and landing by splitting the heavy vehicle into two smaller ones. The standard capsule shape is thus possible for aerocapture and landing on Mars. It is suggested to use the largest possible diameter such that the ballistic coefficient is minimized and the lift to drag ratio is kept small. The maneuvers for the descent and landing are then simplified and the risks are minimized. The scenario has been modified to cope with the new constraints. Different options have been taken into account. It is possible to land a small Mars ascent vehicle or to reuse the habitat lander for Mars ascent. All options perform as well as the others for the criterion of the initial mass in low Earth orbit. However, reusing the habitat lander allows a significant reduction of the size of the Earth return vehicle, which otherwise requires a huge launching capability.

  9. Sociotechnical scenarios for the Austrian energy system

    NASA Astrophysics Data System (ADS)

    Ornetzeder, Michael; Rohracher, Harald; Wächter, Petra

    2012-10-01

    Reducing greenhouse gases by 80%, as demanded by the IPCC, is one of the great long-term challenges facing our societies today and will doubtless require transformative changes to current energy regimes. Large-scale system transitions such as the one envisaged for the global energy system in the next 30-40 years can only be realized through complex processes of change involving global, regional, national, and local levels. In this paper we use sociotechnical scenario analysis to contribute ideas for the transformative change of the current Austrian energy system over the long term and to identify some of the particular policy measures, as well as structural changes and broader shifts in perspective, that would be necessary to deal with such challenges. There is less emphasis on the technical issues involved than on the socio-economic and governance requirements such a shift would demand. We also explain our experiences with the sociotechnical scenario process and its outcomes. In particular, we identify examples of some critical issues and opportunities within one of the identified key action fields and discuss their various implications for energy policy and everyday practices.

  10. Beyond Inflation: A Cyclic Universe Scenario

    NASA Astrophysics Data System (ADS)

    Turok, Neil; Steinhardt, Paul J.

    2005-01-01

    Inflation has been the leading early universe scenario for two decades, and has become an accepted element of the successful `cosmic concordance' model. However, there are many puzzling features of the resulting theory. It requires both high energy and low energy inflation, with energy densities differing by a hundred orders of magnitude. The questions of why the universe started out undergoing high energy inflation, and why it will end up in low energy inflation, are unanswered. Rather than resort to anthropic arguments, we have developed an alternative cosmology, the cyclic universe, in which the universe exists in a very long-lived attractor state determined by the laws of physics. The model shares inflation's phenomenological successes without requiring an epoch of high energy inflation. Instead, the universe is made homogeneous and flat, and scale-invariant adiabatic perturbations are generated during an epoch of low energy acceleration like that seen today, but preceding the last big bang. Unlike inflation, the model requires low energy acceleration in order for a periodic attractor state to exist. The key challenge facing the scenario is that of passing through the cosmic singularity at t = 0. Substantial progress has been made at the level of linearised gravity, which is reviewed here. The challenge of extending this to nonlinear gravity and string theory remains.

  11. Beyond Inflation:. A Cyclic Universe Scenario

    NASA Astrophysics Data System (ADS)

    Turok, Neil; Steinhardt, Paul J.

    2005-08-01

    Inflation has been the leading early universe scenario for two decades, and has become an accepted element of the successful 'cosmic concordance' model. However, there are many puzzling features of the resulting theory. It requires both high energy and low energy inflation, with energy densities differing by a hundred orders of magnitude. The questions of why the universe started out undergoing high energy inflation, and why it will end up in low energy inflation, are unanswered. Rather than resort to anthropic arguments, we have developed an alternative cosmology, the cyclic universe [1], in which the universe exists in a very long-lived attractor state determined by the laws of physics. The model shares inflation's phenomenological successes without requiring an epoch of high energy inflation. Instead, the universe is made homogeneous and flat, and scale-invariant adiabatic perturbations are generated during an epoch of low energy acceleration like that seen today, but preceding the last big bang. Unlike inflation, the model requires low energy acceleration in order for a periodic attractor state to exist. The key challenge facing the scenario is that of passing through the cosmic singularity at t = 0. Substantial progress has been made at the level of linearised gravity, which is reviewed here. The challenge of extending this to nonlinear gravity and string theory remains.

  12. Emergent universe in the braneworld scenario

    NASA Astrophysics Data System (ADS)

    Heydarzade, Y.; Hadi, H.; Darabi, F.; Sheykhi, A.

    2016-06-01

    According to Padmanabhan's proposal, the difference between the surface degrees of freedom and the bulk degrees of freedom in a region of space may result in the acceleration of Universe expansion through the relation Δ V/Δ t = N_sur-N_bulk where N_bulk and N_sur are referred to the degrees of freedom related to the matter and energy content inside the bulk and surface area, respectively (Padmanabhan, arXiv:1206.4916v1, 2012). In this paper, we study the dynamical effect of the extrinsic geometrical embedding of an arbitrary four-dimensional brane in a higher-dimensional bulk space and investigate the corresponding degrees of freedom. Considering the modification of the Friedmann equations arising from a general braneworld scenario, we obtain a correction term in Padmanabhan's relation, denoting the number of degrees of freedom related to the extrinsic geometry of the brane embedded in higher-dimensional spacetime as Δ V /Δ t=N_sur-N_bulk-N_extr where N_extr is for the degree of freedom related to the extrinsic geometry of the brane, while N_sur and N_bulk are defined as before. Finally, we study the validity of the first and second laws of thermodynamics for this general braneworld scenario in the state of thermal equilibrium and in the presence of confined matter fields to the brane with the induced geometric matter fields.

  13. FORMAL SCENARIO DEVELOPMENT FOR ENVIRONMENTAL IMPACT ASSESSMENT STUDIES

    EPA Science Inventory

    Scenario analysis is a process of evaluating possible future events through the consideration of alternative plausible (though not equally likely) outcomes (scenarios). The analysis is designed to enable improved decision-making and assessment through a more rigorous evaluation o...

  14. FORMAL SCENARIO DEVELOPMENT FOR ENVIRONMENTAL IMPACT ASSESSMENT STUDIES

    EPA Science Inventory

    Scenario analysis is a process of evaluating possible future events through the consideration of alternative plausible (though not equally likely) outcomes (scenarios). The analysis is designed to enable improved decision-making and assessment through a more rigorous evaluation o...

  15. An Experiment on Graph Analysis Methodologies for Scenarios

    SciTech Connect

    Brothers, Alan J.; Whitney, Paul D.; Wolf, Katherine E.; Kuchar, Olga A.; Chin, George

    2005-09-30

    Visual graph representations are increasingly used to represent, display, and explore scenarios and the structure of organizations. The graph representations of scenarios are readily understood, and commercial software is available to create and manage these representations. The purpose of the research presented in this paper is to explore whether these graph representations support quantitative assessments of the underlying scenarios. The underlying structure of the scenarios is the information that is being targeted in the experiment and the extent to which the scenarios are similar in content. An experiment was designed that incorporated both the contents of the scenarios and analysts’ graph representations of the scenarios. The scenarios’ content was represented graphically by analysts, and both the structure and the semantics of the graph representation were attempted to be used to understand the content. The structure information was not found to be discriminating for the content of the scenarios in this experiment; but, the semantic information was discriminating.

  16. Assessing Threat Detection Scenarios through Hypothesis Generation and Testing

    DTIC Science & Technology

    2015-12-01

    exercises that measured decision-making performance in a threat detection task. These exercises involved reading threat-relevant scenarios and then... reading threat-relevant scenarios and then reporting threat decisions. Each Soldier read two certain and two uncertain scenarios. After reading each...condone it; see “Checkpoint” and “Election” in Appendix A). After reading each scenario, Soldiers answered two questions (each with two sub

  17. Integrating Future Information through Scenarios. AIR 1985 Annual Forum Paper.

    ERIC Educational Resources Information Center

    Zentner, Rene D.

    The way that higher education planners can take into account changes in the post-industrial society is discussed. The scenario method is proposed as a method of integrating futures information. The planner can be provided with several probable futures, each of which can be incorporated in a scenario. An effective scenario provides the planner…

  18. Effects of Scenario Planning on Participant Mental Models

    ERIC Educational Resources Information Center

    Glick, Margaret B.; Chermack, Thomas J.; Luckel, Henry; Gauck, Brian Q.

    2012-01-01

    Purpose: The purpose of this paper is to assess the effects of scenario planning on participant mental model styles. Design/methodology/approach: The scenario planning literature is consistent with claims that scenario planning can change individual mental models. These claims are supported by anecdotal evidence and stories from the practical…

  19. Integrating Future Information through Scenarios. AIR 1985 Annual Forum Paper.

    ERIC Educational Resources Information Center

    Zentner, Rene D.

    The way that higher education planners can take into account changes in the post-industrial society is discussed. The scenario method is proposed as a method of integrating futures information. The planner can be provided with several probable futures, each of which can be incorporated in a scenario. An effective scenario provides the planner…

  20. Effects of Scenario Planning on Participant Mental Models

    ERIC Educational Resources Information Center

    Glick, Margaret B.; Chermack, Thomas J.; Luckel, Henry; Gauck, Brian Q.

    2012-01-01

    Purpose: The purpose of this paper is to assess the effects of scenario planning on participant mental model styles. Design/methodology/approach: The scenario planning literature is consistent with claims that scenario planning can change individual mental models. These claims are supported by anecdotal evidence and stories from the practical…

  1. Advanced tokamak scenario developments for the next step

    NASA Astrophysics Data System (ADS)

    Joffrin, E.

    2007-12-01

    The objective of advanced tokamak scenario research is to provide a candidate plasma scenario for continuous operation in a fusion power plant. The optimization of the self-generated non-inductive current by the bootstrap mechanism up to a level of 50% and above using high plasma pressure and improved confinement are the necessary conditions to achieve this goal. The two main candidate scenarios for continuous operation, the steady state scenario and long duration (up to 3000 s) high neutron fluency scenario (the hybrid scenario), both face physics challenges in terms of confinement, stability, power exhaust and plasma control. Resistive wall modes and Alfvénic fast ion driven instabilities are the main limitations for operating the steady state scenario at high pressure and low magnetic shear. In addition, this scenario demands a high degree of control over the plasma current and pressure profile and the steady state heat load on in-vessel plasma facing components. Understanding the confinement properties of hybrid scenario is still an outstanding issue as well as its modelling for ITER in particular with regard to the H-mode pedestal parameters. This scenario will also require active current profile control, although, less demanding than for the steady state scenario. To operate advanced tokamak scenario, broad current and pressure profile control appears as a necessary requirement on ITER actuators, in addition to the tools required for instability control such as error field coils or electron cyclotron current drive.

  2. Special Operations Reconnaissance (SOR) Scenario: Intelligence Analysis and Mission Planning

    DTIC Science & Technology

    2008-04-15

    experience in intelligence analysis and mission planning, the SOR scenario was developed to serve as this environment. The scenario is intended to be... intelligence analysis and mission planning scenario that requires a team of three participants to work together to solve various problems in an

  3. Multisite stochastic downscaling of climate model precipitation outputs to high resolution scenarios

    NASA Astrophysics Data System (ADS)

    Bordoy, R.; Burlando, P.

    2011-12-01

    show that, between certain scaling regimes, it is possible to use observed precipitation scaling properties to extrapolate RCMs statistics at resolutions lower than those conventionally provided by RCMs. It is shown that the explored downscaling technique has several advantages over other existing techniques. Among others it allows the investigation of changes of the internal properties of precipitation, thereby including variability and extremes, and the generation of an ensemble of stochastic realizations through a Monte Carlo approach. These features are an advantage over other downscaling procedures since they allow the explicit investigation of uncertainty due to the internal variability of the precipitation process. The results of this novel methodology are presented with regard to future scenarios generation in an alpine catchment in Switzerland using the RCM RegCM3 and the emission scenario A1B for the period 2011-2050.

  4. Influence of future anthropogenic emissions on climate, natural emissions, and air quality

    NASA Astrophysics Data System (ADS)

    Jacobson, Mark Z.; Streets, David G.

    2009-04-01

    This study examines the effects of future anthropogenic emissions on climate, and the resulting feedback to natural emissions and air quality. Speciated sector- and region-specific 2030 emission factors were developed to produce gas and particle emission inventories that followed Special Report on Emission Scenarios (SRES) A1B and B1 emission trajectories. Current and future climate model simulations were run, in which anthropogenic emission changes affected climate, which fed back to natural emissions from lightning (NO, NO2, HONO, HNO3, N2O, H2O2, HO2, CO), soils (dust, bacteria, NO, N2O, H2, CH4, H2S, DMS, OCS, CS2), the ocean (bacteria, sea spray, DMS, N2O, H2, CH4), vegetation (pollen, spores, isoprene, monoterpenes, methanol, other VOCs), and photosynthesis/respiration. New methods were derived to calculate lightning flash rates as a function of size-resolved collisions and other physical principles and pollen, spore, and bacteria emissions. Although the B1 scenario was "cleaner" than the A1B scenario, global warming increased more in the B1 scenario because much A1B warming was masked by additional reflective aerosol particles. Thus neither scenario is entirely beneficial from a climate and health perspective, and the best control measure is to reduce warming gases and warming/cooling particles together. Lightning emissions declined by ˜3% in the B1 scenario and ˜12% in the A1B scenario as the number of ice crystals, thus charge-separating bounceoffs, decreased. Net primary production increased by ˜2% in both scenarios. Emissions of isoprene and monoterpenes increased by ˜1% in the A1B scenario and 4-5% in the B1 scenario. Near-surface ozone increased by ˜14% in the A1B scenario and ˜4% in the B1 scenario, reducing ambient isoprene in the latter case. Gases from soils increased in both scenarios due to higher temperatures. Near-surface PM2.5 mass increased by ˜2% in the A1B scenario and decreased by ˜2% in the B1 scenario. The resulting 1.4% higher

  5. Various problems in lunar habitat construction scenarios

    NASA Astrophysics Data System (ADS)

    Nitta, Keiji; Ohtsubo, Koji; Oguchi, Mitsuo; Ohya, Haruhiko; Kanbe, Seiichiro; Ashida, Akira; Sano, Kenichi

    1991-10-01

    Many papers describing the lunar base construction have been published previously. Lunar base has been considered to be a useful facility to conduct future scientific programs and to get new nuclear energy resource, namely 3He, for defending the environmental collapse on Earth and also to develop lunar resources such as oxygen and nitrogen for extending human activities in space more economically. The scale of the lunar base and the construction methods adopted are determined by the scenario of a lunar utilization program but constrained by the availability of the established space transportation technologies. As indicated in the scenarios described in papers regarding lunar base construction, the first steps of lunar missions are the investigation of lunar itself for conducting scientific research and for surveying the lunar base construction sites, the second steps are the outpost construction for conducting man-tended missions, for more precise scientific research and studying the lunar base construction methods, and third steps are the construction of a permanent base and the expansion of this lunar base for exploiting lunar resources. The missions within the first and second steps are all possible using the ferry (OTV) similar to the service and command modules of Apollo Spacecraft because all necessary weights to be landed on the lunar surface for these missions seem to be under the equivalent weight of the Apollo Lunar Lander. On the other hand, the permanent facilities constructed on the lunar surface in the third step requires larger quantities of construction materials to be transported from Earth, and a new ferry (advanced OTV) having higher transportation ability, at least above 6 times, compared with Apollo Service and Command Modules, are to be developed. The largest problems in the permament lunar base construction are related to the food production facilities, 30-40 m 2 plant cultivation area per person are required for providing the nutrition

  6. Adaptive memory: the survival scenario enhances item-specific processing relative to a moving scenario.

    PubMed

    Burns, Daniel J; Hart, Joshua; Griffith, Samantha E; Burns, Amy D

    2013-01-01

    Nairne, Thompson, and Pandeirada (2007) found that retention of words rated for their relevance to survival is superior to that of words encoded under numerous other deep processing conditions. They suggested that our memory systems might have evolved to confer an advantage for survival-relevant information. Burns, Burns, and Hwang (2011) suggested a two-process explanation of the proximate mechanisms responsible for the survival advantage. Whereas most control tasks encourage only one type of processing, the survival task encourages both item-specific and relational processing. They found that when control tasks encouraged both types of processing, the survival processing advantage was eliminated. However, none of their control conditions included non-survival scenarios (e.g., moving, vacation, etc.), so it is not clear how this two-process explanation would explain the survival advantage when scenarios are used as control conditions. The present experiments replicated the finding that the survival scenario improves recall relative to a moving scenario in both a between-lists and within-list design and also provided evidence that this difference was accompanied by an item-specific processing difference, not a difference in relational processing. The implications of these results for several existing accounts of the survival processing effect are discussed.

  7. Overview of the Biomass Scenario Model

    SciTech Connect

    Peterson, Steve

    2015-09-01

    This report describes the structure of the October 2012 version of the Biomass Scenario Model (BSM) in considerable detail, oriented towards readers with a background or interest in the underlying modeling structures. Readers seeking a less-detailed summary of the BSM may refer to Peterson (2013). BSM aims to provide a framework for exploring the potential contribution of biofuel technologies to the transportation energy supply for the United States over the next several decades. The model has evolved significantly from the prototype developed as part of the Role of Biomass in America" tm s Energy Future (RBAEF) project. BSM represents the supply chain surrounding conversion pathways for multiple fuel products, including ethanol, butanol, and infrastructure-compatible biofuels such as diesel, jet fuel, and gasoline.

  8. Stochastic Optimization for Nuclear Facility Deployment Scenarios

    NASA Astrophysics Data System (ADS)

    Hays, Ross Daniel

    Single-use, low-enriched uranium oxide fuel, consumed through several cycles in a light-water reactor (LWR) before being disposed, has become the dominant source of commercial-scale nuclear electric generation in the United States and throughout the world. However, it is not without its drawbacks and is not the only potential nuclear fuel cycle available. Numerous alternative fuel cycles have been proposed at various times which, through the use of different reactor and recycling technologies, offer to counteract many of the perceived shortcomings with regards to waste management, resource utilization, and proliferation resistance. However, due to the varying maturity levels of these technologies, the complicated material flow feedback interactions their use would require, and the large capital investments in the current technology, one should not deploy these advanced designs without first investigating the potential costs and benefits of so doing. As the interactions among these systems can be complicated, and the ways in which they may be deployed are many, the application of automated numerical optimization to the simulation of the fuel cycle could potentially be of great benefit to researchers and interested policy planners. To investigate the potential of these methods, a computational program has been developed that applies a parallel, multi-objective simulated annealing algorithm to a computational optimization problem defined by a library of relevant objective functions applied to the Ver ifiable Fuel Cycle Simulati on Model (VISION, developed at the Idaho National Laboratory). The VISION model, when given a specified fuel cycle deployment scenario, computes the numbers and types of, and construction, operation, and utilization schedules for, the nuclear facilities required to meet a predetermined electric power demand function. Additionally, it calculates the location and composition of the nuclear fuels within the fuel cycle, from initial mining through

  9. Addressing an Uncertain Future Using Scenario Analysis

    SciTech Connect

    Siddiqui, Afzal S.; Marnay, Chris

    2006-12-15

    The Office of Energy Efficiency and Renewable Energy (EERE) has had a longstanding goal of introducing uncertainty into the analysis it routinely conducts in compliance with the Government Performance and Results Act (GPRA) and for strategic management purposes. The need to introduce some treatment of uncertainty arises both because it would be good general management practice, and because intuitively many of the technologies under development by EERE have a considerable advantage in an uncertain world. For example, an expected kWh output from a wind generator in a future year, which is not exposed to volatile and unpredictable fuel prices, should be truly worth more than an equivalent kWh from an alternative fossil fuel fired technology. Indeed, analysts have attempted to measure this value by comparing the prices observed in fixed-price natural gas contracts compared to ones in which buyers are exposed to market prices (see Bolinger, Wiser, and Golove and (2004)). In addition to the routine reasons for exploring uncertainty given above, the history of energy markets appears to have exhibited infrequent, but troubling, regime shifts, i.e., historic turning points at which the center of gravity or fundamental nature of the system appears to have abruptly shifted. Figure 1 below shows an estimate of how the history of natural gas fired generating costs has evolved over the last three decades. The costs shown incorporate both the well-head gas price and an estimate of how improving generation technology has gradually tended to lower costs. The purpose of this paper is to explore scenario analysis as a method for introducing uncertainty into EERE's forecasting in a manner consistent with the preceding observation. The two questions are how could it be done, and what is its academic basis, if any. Despite the interest in uncertainty methods, applying them poses some major hurdles because of the heavy reliance of EERE on forecasting tools that are deterministic in

  10. [Subjective causal scenarios for global environmental change].

    PubMed

    Böhm, G; Mader, S

    1998-01-01

    Two studies are presented that investigate the assumptions that risk evaluation is based on subjective causal scenarios, and that the cognitive representation of global environmental risks is structured according to five causal levels: human attitudes, human activities, emissions or pollutions, environmental changes, and negative consequences. In study 1, 30 subjects listed in free-response format causes, consequences, and remedial measures for 14 environmental risks. Differences between predictive and diagnostic inferences were found: whereas subjects tend to assign immediate rather than mediated causes, they predominantly assign negative consequences for humans, irrespective of the length of the causal chain that leads to these consequences. In study 2, 41 subjects judged the overall similarity between 25 environmental risks. A multidimensional scaling analysis of these similarity judgments replicates the theoretically assumed five causal levels. Results of both studies support the assumptions that risk evaluation is based on implicit causal hypotheses and that the proposed five-level structure adequately describes the cognitive representation of environmental risks.

  11. A COLLISIONLESS SCENARIO FOR URANUS TILTING

    SciTech Connect

    Boue, Gwenael; Laskar, Jacques

    2010-03-20

    The origin of the high inclination of Uranus' spin-axis (Uranus' obliquity) is one of the great unanswered questions about the solar system. Giant planets are believed to form with nearly zero obliquity, and it has been shown that the present behavior of Uranus' spin is essentially stable. Several attempts were made in order to solve this problem. Here we report numerical simulations showing that Uranus' axis can be tilted during the planetary migration, without the need of a giant impact, provided that the planet had an additional satellite and a temporary large inclination. This might have happened during the giant planet instability phase described in the Nice model. In our scenario, the satellite is ejected after the tilt by a close encounter at the end of the migration. This model can both explain Uranus' large obliquity and bring new constraints on the planet orbital evolution.

  12. The Asymptotic Safety Scenario in Quantum Gravity.

    PubMed

    Niedermaier, Max; Reuter, Martin

    2006-01-01

    The asymptotic safety scenario in quantum gravity is reviewed, according to which a renormalizable quantum theory of the gravitational field is feasible which reconciles asymptotically safe couplings with unitarity. The evidence from symmetry truncations and from the truncated flow of the effective average action is presented in detail. A dimensional reduction phenomenon for the residual interactions in the extreme ultraviolet links both results. For practical reasons the background effective action is used as the central object in the quantum theory. In terms of it criteria for a continuum limit are formulated and the notion of a background geometry self-consistently determined by the quantum dynamics is presented. Self-contained appendices provide prerequisites on the background effective action, the effective average action, and their respective renormalization flows.

  13. Neutralino dark matter from string scenarios

    SciTech Connect

    Cerdeno, D. G.

    2007-01-12

    The direct detection of neutralino dark matter is analysed within the context of orbifold scenarios from the heterotic superstring. In particular, the neutralino-proton cross section is computed and compared with the sensitivity of detectors, taking into account the most recent experimental and astrophysical constraints. In addition to the usual non-universalities of the soft terms in orbifold compactifications, due to their modular weight dependence, the contribution of a D-term, generated by the presence of an anomalous U(1) is also investigated. The D-term contribution provides more flexibility in the non-universalities, and is crucial iniding dangerous charge and colour-breaking minima. Thanks to it, large neutralino detection cross sections can be obtained in regions of the parameter space fulfilling all experimental and astrophysical constraints.

  14. Neutralino dark matter in orbifold scenarios

    SciTech Connect

    Cerdeno, D. G.

    2006-11-28

    The direct detection of neutralino dark matter is analysed within the context of orbifold scenarios from the heterotic superstring. In particular, the theoretical predictions for the neutralino-proton cross section are evaluated and compared with the sensitivity of detectors, taking into account the most recent experimental and astrophysical constraints. In addition to the usual non-universalities of the soft terms in orbifold compactifications, due to their modular weight dependence, the contribution of a D-term, generated by the presence o anomalous U (1) is also investigated. The D-term contribution provides more flexibility in the non-universalities, and is crucial in avoiding dangerous charge and colour-breaking minima. Large neutralino detection cross sections can be obtained in regions of the parameter space fulfilling all experimental and astrophysical constraints thanks to the inclusion of the D-term contribution.

  15. Emergence in holographic scenarios for gravity

    NASA Astrophysics Data System (ADS)

    Dieks, Dennis; van Dongen, Jeroen; de Haro, Sebastian

    2015-11-01

    'Holographic' relations between theories have become an important theme in quantum gravity research. These relations entail that a theory without gravity is equivalent to a gravitational theory with an extra spatial dimension. The idea of holography was first proposed in 1993 by Gerard 't Hooft on the basis of his studies of evaporating black holes. Soon afterwards the holographic 'AdS/CFT' duality was introduced, which since has been intensively studied in the string theory community and beyond. Recently, Erik Verlinde has proposed that even Newton's law of gravitation can be related holographically to the 'thermodynamics of information' on screens. We discuss these scenarios, with special attention to the status of the holographic relation in them and to the question of whether they make gravity and spacetime emergent. We conclude that only Verlinde's scheme straightforwardly instantiates emergence. However, assuming a non-standard interpretation of AdS/CFT may create room for the emergence of spacetime and gravity there as well.

  16. Lyman Alpha Emitters and Galaxy Formation Scenarios

    NASA Astrophysics Data System (ADS)

    Malhotra, S.; Kovac, K.; Somerville, R.; Moustakas, L.; Rhoads, J. E.

    2002-12-01

    The Large Area Lyman Alpha (LALA) survey has successfully identified the population of young Lyman-alpha emitting galaxies predicted about 35 years ago. High equivalent widths of the Lyman-alpha line in these sources suggest that they are a very young (age < 107 years), metal poor, population of stars at redshifts 4.5 and 5.7, making them very interesting objects to study in the context of galaxy formation scenarios. We have begun to do exactly this using the correlation function of LALA galaxies. While the strong correlation function indicates massive halos, the volume density of Lyman-alpha sources and the faint continuum levels indicate low-mass stellar systems. This discrepancy can be resolved by postulating multiple emitters in a single halo.

  17. Inhomogeneous reheating scenario with DBI fields

    NASA Astrophysics Data System (ADS)

    Li, Sheng

    2010-08-01

    We discuss a new mechanism which can be responsible for the origin of the primordial perturbation in inflationary models, the inhomogeneous DBI reheating scenario. Light DBI fields fluctuate during inflation, and finally create the density perturbations through modulation of the inflation decay rate. In this note, we investigate the curvature perturbation and its non-Gaussianity from this new mechanism. Presenting generalized expressions for them, we show that the curvature perturbation not only depends on the particular process of decay but is also dependent on the sound speed cs from the DBI action. More interestingly we find that the non-Gaussianity parameter fNL is independent of cs. As an application we exemplify some decay processes which give a viable and detectable non-Gaussianity. Finally we find a possible connection between our model and the DBI-Curvaton mechanism.

  18. PLASMIX management: LCA of six possible scenarios.

    PubMed

    Cossu, R; Garbo, F; Girotto, F; Simion, F; Pivato, A

    2017-08-09

    Only a small percentage of the separately collected plastic is recycled. The mechanical selection process of source segregated plastic materials generates considerable amounts of residues that are commonly named as Plasmix. By means of a life cycle assessment (LCA) modelling, the environmental performances of the main Plasmix management options (thermal treatment, energy recovery, and landfilling) were compared. Six treatment scenarios, with different pre-treatment alternatives, were evaluated. Landfilling after waste washing and Plasmix substitution of coke in a blast furnace represent the most favorable options, since the performances of thermal treatment and energy recovery are worsened by specific emissions of a variety of toxic compounds and heavy metals within plastic materials as additives. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. New mathematics for the nonadditive Tsallis’ scenario

    NASA Astrophysics Data System (ADS)

    Ferri, G. L.; Pennini, F.; Plastino, A.; Rocca, M. C.

    2017-08-01

    In this paper, we investigate quantum uncertainties in a Tsallis’ nonadditive scenario. To such an end we appeal to q-exponentials (qEs), that are the cornerstone of Tsallis’ theory. In this respect, it is found that some new mathematics is needed and we are led to construct a set of novel special states that are the qE equivalents of the ordinary coherent states (CS) of the harmonic oscillator (HO). We then characterize these new Tsallis’ special states by obtaining the associated (i) probability distributions (PDs) for a state of momentum k, (ii) mean values for some functions of space an momenta and (iii) concomitant quantum uncertainties. The latter are then compared to the usual ones.

  20. Conditional steering under the von Neumann scenario

    NASA Astrophysics Data System (ADS)

    Mukherjee, Kaushiki; Paul, Biswajit; Karmakar, Sumana; Sarkar, Debasis; Mukherjee, Amit; Bhattacharya, Some Sankar; Roy, Arup

    2017-08-01

    In Phys. Lett. A 166, 293 (1992), 10.1016/0375-9601(92)90711-T, Popescu and Rohrlich characterized nonlocality of pure n -partite entangled systems by studying bipartite violation of local realism when n -2 number of parties perform projective measurements on their particles. A pertinent question in this scenario is whether similar characterization is possible for n -partite mixed entangled states also. In the present work we have followed an analogous approach so as to explore whether given a tripartite mixed entangled state the conditional bipartite states obtained by performing projective measurement on the third party demonstrate a weaker form of nonlocality, quantum steering. We also compare this phenomenon of conditional steering with existing notions of tripartite correlations.

  1. Judgments of culpability in a filicide scenario.

    PubMed

    Ferguson, Christopher J; Miller-Stratton, Heather; Heinrich, Emily; Fritz, Stacey; Smith, Shawn

    2008-01-01

    Previous research has indicated that potential jurors are likely to use personal biases, such as those based on gender and ethnicity, in their judgments of culpability of criminal defendants in addition to, or instead of, the facts of the crime. The present paper seeks to extend this literature to the crime of filicide; to examine whether male defendants are judged more harshly than female defendants, as is the case for domestic violence and sexual abuse. 214 participants were provided with a scenario of filicide in which the gender of the perpetrator, the gender of the child, and the family's social class were randomly assigned. Participants were asked to rate the culpability of the defendant in the case. Results indicated that, unlike for other violent crimes, participants did not use gender or social class biases in their judgments of criminal culpability.

  2. Multipartite maximally entangled states in symmetric scenarios

    NASA Astrophysics Data System (ADS)

    González-Guillén, Carlos E.

    2012-08-01

    We consider the class of (N+1)-partite states suitable for protocols where there is a powerful party, the authority, and the other N parties play the same role, namely, the state of their system lies in the symmetric Hilbert space. We show that, within this scenario, there is a “maximally entangled state” that can be transform by a local operations and classical communication protocol into any other state. In addition, we show how to use the protocol efficiently, including the construction of the state, and discuss security issues for possible applications to cryptographic protocols. As an immediate consequence we recover a sequential protocol that implements the 1-to-N symmetric cloning.

  3. Sarin exposure: a simulation case scenario.

    PubMed

    Eason, Martin P

    2013-01-01

    Given the current geopolitical tensions, the risk of a terrorist attack on the United States is constant and increasing. Chemical terrorism, specifically the use of nerve agents, has occurred in other nations. Because of the ease of manufacture, the ability to conceal them, and the lethality of these agents, they pose a potential threat as a weapon of terror. Nerve agent exposure requires prompt recognition, a series of actions to mitigate further exposure to others, and management of the physiological sequelae of exposure. Many civilian healthcare providers are unprepared to manage injuries from nerve exposure. Failure to recognize the signs of nerve agent exposure will increase mortality and morbidity in victims and place healthcare providers at risk. Simulation is an effective methodology to train healthcare personnel in disaster preparedness. This article presents a simulation scenario that reviews the presentation of nerve agent exposure, its management, and a recipe for performing this simulation in a training exercise.

  4. Detecting genuine multipartite entanglement in steering scenarios

    NASA Astrophysics Data System (ADS)

    Jebaratnam, C.

    2016-05-01

    Einstein-Podolsky-Rosen (EPR) steering is a form of quantum nonlocality which is intermediate between entanglement and Bell nonlocality. EPR steering is a resource for quantum key distribution that is device independent on only one side in that it certifies bipartite entanglement when one party's device is not characterized while the other party's device is fully characterized. In this work, we introduce two types of genuine tripartite EPR steering, and derive two steering inequalities to detect them. In a semi-device-independent scenario where only the dimensions of two parties are assumed, the correlations which violate one of these inequalities also certify genuine tripartite entanglement. It is known that Alice can demonstrate bipartite EPR steering to Bob if and only if her measurement settings are incompatible. We demonstrate that quantum correlations can also detect tripartite EPR steering from Alice to Bob and Charlie, even if Charlie's measurement settings are compatible.

  5. Future Scenarios for Mobile Science Learning

    NASA Astrophysics Data System (ADS)

    Burden, Kevin; Kearney, Matthew

    2016-04-01

    This paper adopts scenario planning as a methodological approach and tool to help science educators reconceptualise their use of mobile technologies across various different futures. These `futures' are set out neither as predictions nor prognoses but rather as stimuli to encourage greater discussion and reflection around the use of mobile technologies in science education. Informed by the literature and our empirical data, we consider four alternative futures for science education in a mobile world, with a particular focus on networked collaboration and student agency. We conclude that `seamless learning', whereby students are empowered to use their mobile technologies to negotiate across physical and virtual boundaries (e.g. between school and out-of-school activities), may be the most significant factor in encouraging educators to rethink their existing pedagogical patterns, thereby realizing some of the promises of contextualised participatory science learning.

  6. Lunar transportation scenarios utilising the Space Elevator.

    PubMed

    Engel, Kilian A

    2005-01-01

    The Space Elevator (SE) concept has begun to receive an increasing amount of attention within the space community over the past couple of years and is no longer widely dismissed as pure science fiction. In light of the renewed interest in a, possibly sustained, human presence on the Moon and the fact that transportation and logistics form the bottleneck of many conceivable lunar missions, it is interesting to investigate what role the SE could eventually play in implementing an efficient Earth to Moon transportation system. The elevator allows vehicles to ascend from Earth and be injected into a trans-lunar trajectory without the use of chemical thrusters, thus eliminating gravity loss, aerodynamic loss and the need of high thrust multistage launch systems. Such a system therefore promises substantial savings of propellant and structural mass and could greatly increase the efficiency of Earth to Moon transportation. This paper analyzes different elevator-based trans-lunar transportation scenarios and characterizes them in terms of a number of benchmark figures. The transportation scenarios include direct elevator-launched trans-lunar trajectories, elevator launched trajectories via L1 and L2, as well as launch from an Earth-based elevator and subsequent rendezvous with lunar elevators placed either on the near or on the far side of the Moon. The benchmark figures by which the different transfer options are characterized and evaluated include release radius (RR), required delta v, transfer times as well as other factors such as accessibility of different lunar latitudes, frequency of launch opportunities and mission complexity. The performances of the different lunar transfer options are compared with each other as well as with the performance of conventional mission concepts, represented by Apollo. c2005 Elsevier Ltd. All rights reserved.

  7. Rapid impactor sample return (RISR) mission scenario

    NASA Astrophysics Data System (ADS)

    Walker, James D.; Freitas, Christopher J.; Tapley, Mark B.

    2004-01-01

    Due to the long lead time and great expense of traditional sample return mission plans to Mars or other astronomical bodies, there is a need for a new and innovative way to return materials, potentially at a lower cost. The Rapid Impactor Sample Return (RISR) mission is one such proposal. The general mission scenario involves a single pass of Mars, a Martian moon or an asteroid at high speeds (7 km/s), with the sample return vehicle skimming just 1 or 2 m above a high point (such as a top ridge on Olympus Mons on Mars) and releasing an impactor. The impactor strikes the ground, throwing up debris. The debris with roughly the same forward velocity will be captured by the sample return vehicle and returned to Earth. There is no delay or orbit in the vicinity of Mars or the asteroid: RISR is a one-pass mission. This paper discusses some of the details of the proposal. Calculations are presented that address the question of how much material can be recovered with this technique. There are concerns about the effect of Mars tenuous atmosphere. However, it will be noted that such issues do not occur for RISR style missions to Phobos, Deimos, or asteroids and Near Earth Objects (NEOs). Recent test results in the missile defense community (IFTs 6-8 in 2001, 2002) have scored direct hits at better than 1 m accuracy with closing velocities of 7.6 km/s, giving the belief that accuracy and sensing issues are developed to a point that the RISR mission scenario is feasible.

  8. Lyman Alpha Galaxies and Galaxy Formation Scenarios

    NASA Astrophysics Data System (ADS)

    Malhotra, Sangeeta; Rhoads, James; Dey, Arjun; Jannuzi, Buell

    2003-02-01

    The Large Area Lyman Alpha survey has successfully identified the population of young Lyα emitting galaxies predicted over 30 years ago. High equivalent widths of Lyα line in these sources suggest that they are a very young (age < 10^7 years), metal poor, population of stars at redshifts 4.5, 5.7 and 6.6, making them very interesting objects to study in the context of galaxy formation scenarios. We have begun to do exactly this using the correlation function of LALA galaxies, with fairly puzzling results. Before this leads to more complications in theoretical galaxy formation scenarios, we would like to put the observational results on a firm footing. In order to do that we ask for one night of Keck/Deimos time for spectroscopic confirmation of 50 secure LALA sources at z=4.5, and a similar number of fainter sources, in order to (1) characterize the completeness of this survey, and (2) weed out foreground emission line galaxies which affect the small scale correlation function. The excellent match between wide-field capabilities of DEIMOS and the LALA survey will allow the most complete confirmation and characterization of the high redshift Lyα population yet in terms of photometric sample reliability, while our planned spectra of foreground emission line galaxies will lead to a characterization of emission line selected star-forming galaxies at 0.25 < z < 1.5. We will use our spectroscopic sample to obtain a clean measurement of the small scale correlations among Lyα galaxies (which are clearly seen in our photometric sample). This will let us understand the halo mass, occupancy number, and duty cycle of these objects, and hence better how Lyα sources fit into the bigger picture of galaxy formation.

  9. Climate variability of heat wave and future warming scenario in Taiwan

    NASA Astrophysics Data System (ADS)

    Lin, Chuan-yao

    2017-04-01

    In this study, the heat wave definition and climate variability of HW days according to air temperature are conducted in order to find out the local threshold and variation trends in the past 40 years (1971-2010), in three major cities, Taipei (TP), Taichung (TC) and Kaohsiung (KH) in Taiwan. As for Taiwan's high humidity atmospheric condition, the heat stress index wet-bulb globe temperature (WBGT) is also employed in the past (2003-2012) and future warming scenario in 2075-2099. The simulation WBGT in the past (2003-2012) and future warming projection (2075-2099) are deduced from the results of ECHAM5/MPIOM-WRF (ECW) dynamic downscaling 5-km resolution in these three cities. Box plot analyzing shows the differences between observed and simulated WBGT distribution at 25%, 50% and 75% percentiles are all within 0.7 °C in 2003-2012. Even the extreme values, the differences are all within 0.9 °C. In other words, the ranges of the WBGT variation from observations are reasonably captured by the ECW in three cities. According to the good performance of ECW in the WBGT simulation, the projection of future WBGT in these three cities has been evaluated under IPCC A1B scenario by using ECW. It is estimated that nearly 50% of the days in summer (July and August) are all at the level of danger (WBGT>31 °C ) at the period 2075-2099.It is a significant increase because they are only 10.74%, 4.22% and 11.28% above this level in the past in 2003-2012 in TP, TC and KH, respectively. From public health point of view, the impacts are huge and worthy to pay attention under the global warming trend.

  10. Daily precipitation in a changing climate: lessons learnt from Swiss national climate change scenario initiatives

    NASA Astrophysics Data System (ADS)

    Fischer, Andreas; Liniger, Mark; Zubler, Elias; Keller, Denise; Rajczak, Jan; Schär, Christoph

    2015-04-01

    Precipitation is a key variable in the climate system that affects many aspects of the hydrological cycle such as river runoff, snow amount, or droughts. Climate change projections of precipitation and related impacts are therefore of fundamental concern for multiple sectors in many regions. Within the Swiss national climate change initiatives CH2011 and CH2014, several precipitation-dependent impacts were quantitatively assessed. This included consideration of projections of the mean annual cycle, as well as changes in extremes, wet-day frequency, and spell lengths. To better understand the needs of the primary and intermediary users of climate model data in Switzerland, a dialogue between the climate modeling and impact communities was established over recent years. In this presentation, we like to report about our experience with these needs, and on the steps we undertook to approach the emerging challenges regarding changes in precipitation. In our work beyond CH2011, the multi-faceted characteristics of precipitation change over Switzerland are investigated based on the joint analysis of several regional climate model (RCM) simulations from ENSEMBLES at the A1B emission scenario. In some seasons, changes in precipitation frequency and intensity compensate each other, in other seasons just one of these two components changes. Yet, extreme daily precipitation events are projected to intensify in most seasons. In summer, a reduction of frequency yields an augmented risk of more multi-day dry spells and meteorological summer droughts. It is also in summer, when the model simulations exhibit an elevation-dependent shift in precipitation type toward more convective precipitation. To accommodate the common need of many end-users in obtaining quantitative future projection data at multiple stations, we use a stochastic multi-site precipitation generator as main downscaling technique. In the presentation, we will present first results thereof and discuss, how end

  11. The NorWeST Stream Temperature Database, Model, and Climate Scenarios for the Northwest U.S. (Invited)

    NASA Astrophysics Data System (ADS)

    Isaak, D.; Wenger, S.; Peterson, E.; Ver Hoef, J.; Luce, C.; Hostetler, S. W.; Kershner, J.; Dunham, J.; Nagel, D.; Roper, B.

    2013-12-01

    Anthropogenic climate change is warming the Earth's rivers and streams and threatens significant changes to aquatic biodiversity. Effective threat response will require prioritization of limited conservation resources and coordinated interagency efforts guided by accurate information about climate, and climate change, at scales relevant to the distributions of species across landscapes. Here, we describe the NorWeST (i.e., NorthWest Stream Temperature) project to develop a comprehensive interagency stream temperature database and high-resolution climate scenarios across Washington, Oregon, Idaho, Montana, and Wyoming (~400,000 stream kilometers). The NorWeST database consists of stream temperature data contributed by >60 state, federal, tribal, and private resource agencies and may be the largest of its kind in the world (>45,000,000 hourly temperature recordings at >15,000 unique monitoring sites). These data are being used with spatial statistical network models to accurately downscale (R2 = 90%; RMSE < 1 C) global climate patterns to all perennially flowing reaches within river networks at 1-kilometer resolution. Historic stream temperature scenarios are developed using air temperature data from RegCM3 runs for the NCEP historical reanalysis and future scenarios (2040s and 2080s) are developed by applying bias corrected air temperature and discharge anomalies from ensemble climate and hydrology model runs for A1B and A2 warming trajectories. At present, stream temperature climate scenarios have been developed for 230,000 stream kilometers across Idaho and western Montana using data from more than 7,000 monitoring sites. The raw temperature data and stream climate scenarios are made available as ArcGIS geospatial products for download through the NorWeST website as individual river basins are completed (http://www.fs.fed.us/rm/boise/AWAE/projects/NorWeST.shtml). By providing open access to temperature data and scenarios, the project is fostering new research on

  12. Advances on modelling of ITER scenarios: physics and computational challenges

    NASA Astrophysics Data System (ADS)

    Giruzzi, G.; Garcia, J.; Artaud, J. F.; Basiuk, V.; Decker, J.; Imbeaux, F.; Peysson, Y.; Schneider, M.

    2011-12-01

    Methods and tools for design and modelling of tokamak operation scenarios are discussed with particular application to ITER advanced scenarios. Simulations of hybrid and steady-state scenarios performed with the integrated tokamak modelling suite of codes CRONOS are presented. The advantages of a possible steady-state scenario based on cyclic operations, alternating phases of positive and negative loop voltage, with no magnetic flux consumption on average, are discussed. For regimes in which current alignment is an issue, a general method for scenario design is presented, based on the characteristics of the poloidal current density profile.

  13. Methods for interfacing IPCC climate change scenarios with higher resolution watershed management models in the Ethiopian Blue Nile Basin

    NASA Astrophysics Data System (ADS)

    Easton, Z. M.; MacAlister, C.; Fuka, D. R.

    2013-12-01

    As much as 90% of the Nile River flow that reaches Egypt originates in the Highlands of the Ethiopian Blue Nile Basin. This imbalance in water availability poses a threat to water security in the region, and could be severely impacted by projected climate change. This analysis coupled hydrodynamic/watershed models with the Intergovernmental Panel on Climate Change (IPCC) AR4 climate change scenarios to assess the potential impact on water resources and sediment dynamics. Specific AR4 scenarios include the A1B, B1, B2 and COMMIT, which were used to force the baseline hydrodynamic models calibrated against 1979-2011 streamflow for 20 sub-watersheds in the Tana and Beles basins. Transfer functions were developed to distribute the model parameters from the calibrated sub-watersheds to un-gauged portions of the basins based on a similarity index of hydrologic response units. We analyzed the scenario in two manners: first we ran all of the seven individual Global Circulation Model results in the IPCC AR4 report though our watershed models to asses the potential spread of climate change predictions; then we assessed the mean value produced for each IPCC AR4 scenario to better estimate convergence. Results indicate that the Tana basin is expected to experience an increase in mean annual flow. The Beles basin is predicted to experience a small decrease in mean annual flow. Sediment concentrations in the Tana basin increase proportionally more than the flow increase. Interestingly, and perhaps counter to what might be expected for a decrease in flow in the Beles basin, sediment concentrations increase.

  14. Impact of explosive eruption scenarios at Vesuvius

    NASA Astrophysics Data System (ADS)

    Zuccaro, G.; Cacace, F.; Spence, R. J. S.; Baxter, P. J.

    2008-12-01

    In the paper the first attempt at the definition of a model to assess the impact of a range of different volcanic hazards on the building structures is presented. This theoretical approach has been achieved within the activities of the EXPLORIS Project supported by the EU. A time history for Sub-Plinian I eruptive scenario of the Vesuvius is assumed by taking advantage of interpretation of historical reports of volcanic crises of the past [Carafa, G. 1632. In opusculum de novissima Vesuvij conflagratione, epistola isagogica, 2 a ed. Napoli, Naples; Mascolo, G.B., 1634. De incendio Vesuvii excitato xvij. Kal. Ianuar. anno trigesimo primo sæculi Decimiseptimi libri X. Cum Chronologia superiorum incendiorum; & Ephemeride ultimi. Napoli; Varrone, S., 1634. Vesuviani incendii historiae libri tres. Napoli], numerical simulations [Neri, A., Esposti Ongaro, T., Macedonio, G., Gidaspow, D., 2003. Multiparticle simulation of collapsing volcanic columns and pyroclastic flows. J. Geophys. Res. Lett. 108, 2202. doi:10.1029/2001 JB000508; Macedonio, G., Costa, A., Longo, A., 2005. HAZMAP: a computer model for volcanic ash fallout and assessment of subsequent hazard. Comput. Geosci. 31,837-845; Costa, A., Macedonio, G., Folch, A., 2006. A three-dimensional Eulerian model for transport and deposition of volcanic ashes. Earth Planet. Sci. Lett. 241,634-647] and experts' elicitations [Aspinall, W.P., 2006. Structured elicitation of expert judgment for probabilistic hazard and risk assessment in volcanic eruptions. In: Mader, H.M. Coles, S.G. Connor, C.B. Connor, L.J. (Eds), Statistics in Volcanology. Geological Society of London on behalf of IAVCEI, pp.15-30; Woo, G., 1999. The Mathematics of Natural Catastrophes. Imperial College Press, London] from which the impact on the building structures is derived. This is achieved by an original definition of vulnerability functions for multi-hazard input and a dynamic cumulative damage model. Factors affecting the variability of the final

  15. Climate mitigation scenarios of drained peat soils

    NASA Astrophysics Data System (ADS)

    Kasimir Klemedtsson, Åsa; Coria, Jessica; He, Hongxing; Liu, Xiangping; Nordén, Anna

    2014-05-01

    The national inventory reports (NIR) submitted to the UNFCCC show Sweden - which as many other countries has wetlands where parts have been drained for agriculture and forestry purposes, - to annually emit 12 million tonnes carbon dioxide equivalents, which is more GHG'es than industrial energy use release in Sweden. Similar conditions can be found in other northern countries, having cool and wet conditions, naturally promoting peat accumulation, and where land use management over the last centuries have promoted draining activities. These drained peatland, though covering only 2% of the land area, have emissions corresponding to 20% of the total reported NIR emissions. This substantial emission contribution, however, is hidden within the Land Use Land Use Change and Forestry sector (LULUCF) where the forest Carbon uptake is even larger, which causes the peat soil emissions become invisible. The only drained soil emission accounted in the Swedish Kyoto reporting is the N2O emission from agricultural drained organic soils of the size 0.5 million tonnes CO2e yr-1. This lack of visibility has made incentives for land use change and management neither implemented nor suggested, however with large potential. Rewetting has the potential to decrease soil mineralization, why CO2 and N2O emissions are mitigated. However if the soil becomes very wet CH4 emission will increase together with hampered plant growth. By ecological modeling, using the CoupModel the climate change mitigation potential have been estimated for four different land use scenarios; 1, Drained peat soil with Spruce (business as usual scenario), 2, raised ground water level to 20 cm depth and Willow plantation, 3, raised ground water level to 10 cm depth and Reed Canary Grass, and 4, rewetting to an average water level in the soil surface with recolonizing wetland plants and mosses. We calculate the volume of biomass production per year, peat decomposition, N2O emission together with nitrate and DOC

  16. A Water Rich Mars Surface Mission Scenario

    NASA Technical Reports Server (NTRS)

    Hoffman, Stephen J.; Andrews, Alida; Joosten, B. Kent; Watts, Kevin

    2017-01-01

    In an on-going effort to make human Mars missions more affordable and sustainable, NASA continues to investigate the innovative leveraging of technological advances in conjunction with the use of accessible Martian resources directly applicable to these missions. One of the resources with the broadest utility for human missions is water. Many past studies of human Mars missions assumed a complete lack of water derivable from local sources. However, recent advances in our understanding of the Martian environment provides growing evidence that Mars may be more "water rich" than previously suspected. This is based on data indicating that substantial quantities of water are mixed with surface regolith, bound in minerals located at or near the surface, and buried in large glacier-like forms. This paper describes an assessment of what could be done in a "water rich" human Mars mission scenario. A description of what is meant by "water rich" in this context is provided, including a quantification of the water that would be used by crews in this scenario. The different types of potential feedstock that could be used to generate these quantities of water are described, drawing on the most recently available assessments of data being returned from Mars. This paper specifically focuses on sources that appear to be buried quantities of water ice. (An assessment of other potential feedstock materials is documented in another paper.) Technologies and processes currently used in terrestrial Polar Regions are reviewed. One process with a long history of use on Earth and with potential application on Mars - the Rodriguez Well - is described and results of an analysis simulating the performance of such a well on Mars are presented. These results indicate that a Rodriguez Well capable of producing the quantities of water identified for a "water rich" human mission are within the capabilities assumed to be available on the Martian surface, as envisioned in other comparable Evolvable

  17. A Water Rich Mars Surface Mission Scenario

    NASA Technical Reports Server (NTRS)

    Hoffman, Stephen; Andrews, Alida; Joosten, Kent; Watts, Kevin

    2017-01-01

    The surface of Mars once had abundant water flowing on its surface, but now there is a general perception that this surface is completely dry. Several lines of research have shown that there are sources of potentially large quantities of water at many locations on the surface, including regions considered as candidates for future human missions. Traditionally, system designs for these human missions are constrained to tightly recycle water and oxygen, and current resource utilization strategies involve ascent vehicle oxidizer production only. But the assumption of relatively abundant extant water may change this. Several scenarios were constructed to evaluate water requirements for human Mars expeditions to assess the impact to system design if locally produced water is available. Specifically, we have assessed water resources needed for 1) ascent vehicle oxidizer and fuel production, 2) open-loop water and oxygen life support requirements along with more robust usage scenarios, and 3) crew radiation protection augmentation. In this assessment, production techniques and the associated chemistry to transform Martian water and atmosphere into these useful commodities are identified, but production mass and power requirements are left to future analyses. The figure below illustrates the type of water need assessment performed and that will be discussed. There have been several sources of feedstock material discussed in recent literature that could be used to produce these quantities of water. This paper will focus on Mars surface features that resemble glacier-like forms on Earth. Several lines of evidence indicate that some of these features are in fact buried ice, likely remnants from an earlier ice age on Mars. This paper examines techniques and hardware systems used in the polar regions of Earth to access this buried ice and withdraw water from it. These techniques and systems will be described to illustrate options available. A technique known as a Rodriguez Well

  18. Projected hydrologic changes in monsoon-dominated Himalaya Mountain basins with changing climate and deforestation

    NASA Astrophysics Data System (ADS)

    Neupane, Ram P.; White, Joseph D.; Alexander, Sara E.

    2015-06-01

    In mountain headwaters, climate and land use changes affect short and long term site water budgets with resultant impacts on landslide risk, hydropower generation, and sustainable agriculture. To project hydrologic change associated with climate and land use changes in the Himalaya Mountains, we used the Soil and Water Assessment Tool (SWAT) calibrated for the Tamor and Seti River basins located at eastern and western margins of Nepal. Future climate change was modeled using averaged temperature and precipitation for 2080 derived from Special Report on Emission Scenarios (SRES) (B1, A1B and A2) of 16 global circulation models (GCMs). Land use change was modeled spatially and included expansion of (1) agricultural land, (2) grassland, and (3) human settlement area that were produced by considering existing land use with projected changes associated with viability of elevation and slope characteristics of the basins capable of supporting different land use type. From these simulations, higher annual stream discharge was found for all GCM-derived scenarios compared to a baseline simulation with maximum increases of 13 and 8% in SRES-A2 and SRES-A1B for the Tamor and Seti basins, respectively. On seasonal basis, we assessed higher precipitation during monsoon season in all scenarios that corresponded with higher stream discharge of 72 and 68% for Tamor and Seti basins, respectively. This effect appears to be geographically important with higher influence in the eastern Tamor basin potentially due to longer and stronger monsoonal period of that region. However, we projected minimal changes in stream discharge for the land use scenarios potentially due to higher water transmission to groundwater reservoirs associated with fractures of the Himalaya Mountains rather than changes in surface runoff. However, when combined the effects of climate and land use changes, discharge was moderately increased indicating counteracting mechanisms of hydrologic yield in these mountains

  19. Undulator Hall Air Temperature Fault Scenarios

    SciTech Connect

    Sevilla, J.; Welch, J.; /SLAC

    2010-11-17

    Recent experience indicates that the LCLS undulator segments must not, at any time following tuning, be allowed to change temperature by more than about {+-}2.5 C or the magnetic center will irreversibly shift outside of acceptable tolerances. This vulnerability raises a concern that under fault conditions the ambient temperature in the Undulator Hall might go outside of the safe range and potentially could require removal and retuning of all the segments. In this note we estimate changes that can be expected in the Undulator Hall air temperature for three fault scenarios: (1) System-wide power failure; (2) Heating Ventilation and Air Conditioning (HVAC) system shutdown; and (3) HVAC system temperature regulation fault. We find that for either a system-wide power failure or an HVAC system shutdown (with the technical equipment left on), the short-term temperature changes of the air would be modest due to the ability of the walls and floor to act as a heat ballast. No action would be needed to protect the undulator system in the event of a system-wide power failure. Some action to adjust the heat balance, in the case of the HVAC power failure with the equipment left on, might be desirable but is not required. On the other hand, a temperature regulation failure of the HVAC system can quickly cause large excursions in air temperature and prompt action would be required to avoid damage to the undulator system.

  20. Scenario Tools For Efficient Eutrophication Management

    NASA Astrophysics Data System (ADS)

    Arheimer, B.; Vastra SP3 Team

    Several possible measures are available to reduce diffuse (non-point source) nutri- ent load to surface water and thereby reduce eutrophication. Such measures include changed arable practices and constructions of wetlands and buffer zones in the land- scape, as well as managing lake ecosystems. In some cases, such as for wetlands, there is an intense debate regarding the efficiency of their nutrient reducing capability. In ad- dition, the combined effect of several measures in a catchment is not necessarily equal to their sum. It is therefore important to apply a holistic and integrated catchment approach when applying and evaluating different management strategies. To facili- tate such catchment analyses, the Swedish water management research programme (VASTRA) develop modelling tools addressing both phosphorus (P) and nitrogen (N) dynamics in catchments. During the last three years decision support tools for N man- agement in rivers and lakes have been developed (e.g., HBV-N, BIOLA) and applied in scenarios to demonstrate the effect of various reducing measures. At present, similar tools for P are under development. This presentation will demonstrate the VASTRA tool-box and its applications for efficient eutrophication management.

  1. [Environmental management: critical analysis, scenarios and challenges].

    PubMed

    Porto, Marcelo Firpo de Souza; Schütz, Gabriel Eduardo

    2012-06-01

    This article discusses the limits, alternatives and challenges of environmental management in contemporary globalized capitalist societies. It is based on a critical analysis supported by authors from social sciences, political ecology and public health. To this end, we systematize the meaning of hegemonic environmental management in terms of eco-efficiency and its limits to tackle environmental risks and construct democratic processes and societies. We developed four ideal scenarios involving possible combinations of environmental management and democracy. This model served as a base, together with academic studies and the theoretical and militant experience of the authors, for a reflection on the current characteristics and future trends of environmental management and democracy, with emphasis on the reality of Latin America, specifically Brazil. Lastly, we discuss possibilities for social transformation taking into consideration the contradictions and emancipatory alternatives resulting from confrontations between hegemonic tendencies of the market and counter-hegemonic utopias and social movements. The latter assume principles of environmental justice, economic solidarity, agro-ecology and sustainability as well as the construction of new epistemologies.

  2. UAV team behaviors in operational scenarios

    NASA Astrophysics Data System (ADS)

    Gilmore, John F.; Garbarino, Joseph E.

    2004-09-01

    The Behavior Enhanced Heterogeneous Autonomous Vehicle Environment (BEHAVE) is a distributed system for the command and control of multiple Unmanned Vehicle Systems (UVS) with various sensor payloads (EO, infrared and radar) and mission roles (combat, reconnaissance, penetrator, relay) working in cooperation to fulfill mission goals in light of encountered threats, vehicle damage, and mission redirects. In its current form, BEHAVE provides UVS dynamic route planning/replanning, autonomous vehicle control, platform self-awareness, autonomous threat response, and muti-vehicle cooperation. This paper focuses on BEHAVE's heterogeneous autonomous UVS team cooperation achieved through the transformation of UVS operational doctrine into UVS team behaviors. This level of tactics provides the initial high-level cooperative control guidance and plans for multiple UVSs operating to achieve specific mission goal. BEHAVE's heterogeneous UVS behaviors include inter-vehicle cueing capability on coupled missions based on new threats, targets, and foreshadowing changes in environments, optimizing individual UVS mission roles, enhanced reassignment of mission goals based upon resources consumed and threats encountered, and multi UVS team threat behavior. Threat behaviors include logic incorporated for team scenarios such as drawing out or confusing threats.

  3. Realities of leprosy control: updating scenarios.

    PubMed

    Gonçalves, Aguinaldo

    2013-09-01

    In the light of successive therapeutical difficulties for leprosy control, the application of drug therapy combination over the last decades has brought about an expectation of cure for leprosy patients and also for the elimination of this illness as a Public Health problem. However, there has been a progressive reduction in the prevalence of leprosy, but without any apparent impact on transmission, which has led to recognized need for solid assessment of respective epidemiological evidence as grounds for interventions to solve the problem. In this regard, here we present a retroanalytical qualitative and quantitative study, combined with a prospective diachronic approach, based on the association of documental review techniques and analysis of content, involving the following phases in succession: assembly of an operational scheme, execution of search strategy, application of criteria, selection of studies, data extraction and processing, implementation of analysis plan and preparation of final text. The appropriate execution of the procedures, as applied, allows us to obtain and discuss the identification of three main scenarios: the elimination of the illness as a public health problem (Neglected Illness); therapeutic aspects (Resistance; Relapse; Non-Adherence; Persistence) and complexity (complications and physical incapacities). The conclusions that have been reached indicate,mainly, that the reality of leprosy control with the use of combination drug therapy, still needs to be handled with care, even more so as this is just a fragment of the set of people once under medical attention, which also correspond to a parcel of the set of people affected by the ailment.

  4. Realistic Ground Motion Scenarios: Methodological Approach

    SciTech Connect

    Nunziata, C.; Peresan, A.; Romanelli, F.; Vaccari, F.; Zuccolo, E.; Panza, G. F.

    2008-07-08

    The definition of realistic seismic input can be obtained from the computation of a wide set of time histories, corresponding to possible seismotectonic scenarios. The propagation of the waves in the bedrock from the source to the local laterally varying structure is computed with the modal summation technique, while in the laterally heterogeneous structure the finite difference method is used. The definition of shear wave velocities within the soil cover is obtained from the non-linear inversion of the dispersion curve of group velocities of Rayleigh waves, artificially or naturally generated. Information about the possible focal mechanisms of the sources can be obtained from historical seismicity, based on earthquake catalogues and inversion of isoseismal maps. In addition, morphostructural zonation and pattern recognition of seismogenic nodes is useful to identify areas prone to strong earthquakes, based on the combined analysis of topographic, tectonic, geological maps and satellite photos. We show that the quantitative knowledge of regional geological structures and the computation of realistic ground motion can be a powerful tool for a preventive definition of the seismic hazard in Italy. Then, the formulation of reliable building codes, based on the evaluation of the main potential earthquakes, will have a great impact on the effective reduction of the seismic vulnerability of Italian urban areas, validating or improving the national building code.

  5. Nonlocal correlations in a macroscopic measurement scenario

    NASA Astrophysics Data System (ADS)

    Kunkri, Samir; Banik, Manik; Ghosh, Sibasish

    2017-02-01

    Nonlocality is one of the main characteristic features of quantum systems involving more than one spatially separated subsystem. It is manifested theoretically as well as experimentally through violation of some local realistic inequality. On the other hand, classical behavior of all physical phenomena in the macroscopic limit gives a general intuition that any physical theory for describing microscopic phenomena should resemble classical physics in the macroscopic regime, the so-called macrorealism. In the 2-2-2 scenario (two parties, with each performing two measurements and each measurement having two outcomes), contemplating all the no-signaling correlations, we characterize which of them would exhibit classical (local realistic) behavior in the macroscopic limit. Interestingly, we find correlations which at the single-copy level violate the Bell-Clauser-Horne-Shimony-Holt inequality by an amount less than the optimal quantum violation (i.e., Cirel'son bound 2 √{2 } ), but in the macroscopic limit gives rise to a value which is higher than 2 √{2 } . Such correlations are therefore not considered physical. Our study thus provides a sufficient criterion to identify some of unphysical correlations.

  6. Knowledge sharing in the health scenario

    PubMed Central

    2014-01-01

    The understanding of certain data often requires the collection of similar data from different places to be analysed and interpreted. Interoperability standards and ontologies, are facilitating data interchange around the world. However, beyond the existing networks and advances for data transfer, data sharing protocols to support multilateral agreements are useful to exploit the knowledge of distributed Data Warehouses. The access to a certain data set in a federated Data Warehouse may be constrained by the requirement to deliver another specific data set. When bilateral agreements between two nodes of a network are not enough to solve the constraints for accessing to a certain data set, multilateral agreements for data exchange are needed. We present the implementation of a Multi-Agent System for multilateral exchange agreements of clinical data, and evaluate how those multilateral agreements increase the percentage of data collected by a single node from the total amount of data available in the network. Different strategies to reduce the number of messages needed to achieve an agreement are also considered. The results show that with this collaborative sharing scenario the percentage of data collected dramaticaly improve from bilateral agreements to multilateral ones, up to reach almost all data available in the network. PMID:25471452

  7. Adapting water allocation management to drought scenarios

    NASA Astrophysics Data System (ADS)

    Giacomelli, P.; Rossetti, A.; Brambilla, M.

    2008-04-01

    Climate change dynamics have significant consequences on water resources on a watershed scale. With water becoming scarcer and susceptible to variation, the planning and reallocation decisions in watershed management need to be reviewed. This research focuses on an in-depth understanding of the current allocation balance of water resources among competitors, placed along the course of the Adda River. In particular, during the summer period, the demand for water dramatically increases. This is due to the increase in irrigation activities in the lower part of the basin and to the highest peaks of tourist inflow, in the Como Lake and Valtellina areas. Moreover, during these months, the hydroelectric reservoirs in the upper part of the Adda River basin (the Valtellina) retain most of the volume of water coming from the snow and glacier melt. The existing allocation problem among these different competing users is exacerbated by the decreasing water supplies. The summer of 2003 testified the rise in a number of allocation problems and situations of water scarcity that brought about environmental and economical consequences. The RICLIC project is committed to the understanding of water dynamics on a regional scale, to quantify the volumes involved and offer local communities an instrument to improve a sustainable water management system, within uncertain climate change scenarios.

  8. Scenario of Architectural Education in India

    NASA Astrophysics Data System (ADS)

    Dua, S.; Chahal, K. S.

    2014-09-01

    The dictionary meaning of education is to develop mentally and morally. A good holistic architectural education, therefore, is a combination of skills, information, as well as values. It is somewhat unique. The evaluation process is continuous in nature and in addition to the traditional means of assessment, the training in architectural education consists of varied interrelated parts-theory, field visit and studio/workshop. To certain extent the subjective nature of the design studio projects provides challenges and opportunities for both students and faculty members, in terms of acquiring necessary skills at the part of the students, and, necessity to update and upgrade continually with the changing pace at the part of the teachers. Technology continues to grow at a rapid pace; equipping the students to meet the complex demands of the profession; the curriculum structure and focus and value system must facilitate the relationship between general education and specialized study. Architects must acquire and understand the required information and find ways to put it in order and apply it to particular settings especially in this era of MNCs and BPOs. The paper discusses the current scenario of architectural education in India and affirms the need for change in this education from generalized study which had been in practice in twentieth century to a more relevant, specialised, and value-based education addressing technical and humanistic challenges more objectively in these vastly changing, socio-economic and political trends at global and regional levels.

  9. Hyperspectral Anomaly Detection in Urban Scenarios

    NASA Astrophysics Data System (ADS)

    Rejas Ayuga, J. G.; Martínez Marín, R.; Marchamalo Sacristán, M.; Bonatti, J.; Ojeda, J. C.

    2016-06-01

    We have studied the spectral features of reflectance and emissivity in the pattern recognition of urban materials in several single hyperspectral scenes through a comparative analysis of anomaly detection methods and their relationship with city surfaces with the aim to improve information extraction processes. Spectral ranges of the visible-near infrared (VNIR), shortwave infrared (SWIR) and thermal infrared (TIR) from hyperspectral data cubes of AHS sensor and HyMAP and MASTER of two cities, Alcalá de Henares (Spain) and San José (Costa Rica) respectively, have been used. In this research it is assumed no prior knowledge of the targets, thus, the pixels are automatically separated according to their spectral information, significantly differentiated with respect to a background, either globally for the full scene, or locally by image segmentation. Several experiments on urban scenarios and semi-urban have been designed, analyzing the behaviour of the standard RX anomaly detector and different methods based on subspace, image projection and segmentation-based anomaly detection methods. A new technique for anomaly detection in hyperspectral data called DATB (Detector of Anomalies from Thermal Background) based on dimensionality reduction by projecting targets with unknown spectral signatures to a background calculated from thermal spectrum wavelengths is presented. First results and their consequences in non-supervised classification and extraction information processes are discussed.

  10. Knowledge sharing in the health scenario.

    PubMed

    Lluch-Ariet, Magí; Brugués de la Torre, Albert; Vallverdú, Francesc; Pegueroles-Vallés, Josep

    2014-11-28

    The understanding of certain data often requires the collection of similar data from different places to be analysed and interpreted. Interoperability standards and ontologies, are facilitating data interchange around the world. However, beyond the existing networks and advances for data transfer, data sharing protocols to support multilateral agreements are useful to exploit the knowledge of distributed Data Warehouses. The access to a certain data set in a federated Data Warehouse may be constrained by the requirement to deliver another specific data set. When bilateral agreements between two nodes of a network are not enough to solve the constraints for accessing to a certain data set, multilateral agreements for data exchange are needed. We present the implementation of a Multi-Agent System for multilateral exchange agreements of clinical data, and evaluate how those multilateral agreements increase the percentage of data collected by a single node from the total amount of data available in the network. Different strategies to reduce the number of messages needed to achieve an agreement are also considered. The results show that with this collaborative sharing scenario the percentage of data collected dramaticaly improve from bilateral agreements to multilateral ones, up to reach almost all data available in the network.

  11. Dynamical Scenarios for Chromosome Bi-orientation

    PubMed Central

    Zhang, Tongli; Oliveira, Raquel A.; Schmierer, Bernhard; Novák, Béla

    2013-01-01

    Chromosome bi-orientation at the metaphase spindle is essential for precise segregation of the genetic material. The process is error-prone, and error-correction mechanisms exist to switch misaligned chromosomes to the correct, bi-oriented configuration. Here, we analyze several possible dynamical scenarios to explore how cells might achieve correct bi-orientation in an efficient and robust manner. We first illustrate that tension-mediated feedback between the sister kinetochores can give rise to a bistable switch, which allows robust distinction between a loose attachment with low tension and a strong attachment with high tension. However, this mechanism has difficulties in explaining how bi-orientation is initiated starting from unattached kinetochores. We propose four possible mechanisms to overcome this problem (exploiting molecular noise; allowing an efficient attachment of kinetochores already in the absence of tension; a trial-and-error oscillation; and a stochastic bistable switch), and assess their impact on the bi-orientation process. Based on our results and supported by experimental data, we put forward a trial-and-error oscillation and a stochastic bistable switch as two elegant mechanisms with the potential to promote bi-orientation both efficiently and robustly. PMID:23790367

  12. Future seasonal climate change scenarios for Taiwan using a climate scenario generator

    NASA Astrophysics Data System (ADS)

    Tfwala, Samkele; Chen, Su-Chin

    2017-04-01

    Decision makers, resource managers and engineers demand accurate information regarding future changes in climate and variability to better forecast potential impacts. To acquire information about climate change, dedicated experiments using global and regional climate models are needed. These demand considerable computing capacity and expertise. This study explores the use of simple climate change scenario generators in developing future changes of climate change at national level. Model for the Assessment of Greenhouse-gas Induced Climate Change (MAGGIC) combined with a scenario generator (SCENGEN) is applied. MAGGIC/SCENGEN use results from the Coupled Model Inter-comparison Project Phase 3 - CMIP3 and IPCC fourth assessment report, working group 1 - AR4). Eighteen general circulation models (GCMs) were evaluated based on global and regional performance. From these, 5 models were selected to predict future changes for Taiwan. The models predict temperature increase in all seasons with a high magnitude (3.16 °C) in June-July-August (JJA) season. Precipitation changes vary widely; generally, there is a decline in December-January-February (DJF), March-April-May (MAM) and September-October-November (SON). A significant decline, -8.8 % and -16 %, is observed in MAM by 2020 and 2100, respectively. The study reveals that simple climate change scenarios can be used to predict future changes.

  13. Climate change scenarios of temperature and precipitation over five Italian regions for the period 2021-2050 obtained by statistical downscaling models

    NASA Astrophysics Data System (ADS)

    Tomozeiu, R.; Tomei, F.; Villani, G.; Pasqui, M.

    2010-09-01

    Climate change scenarios of seasonal maximum, minimum temperature and precipitation in five Italian regions, over the period 2021-2050 against 1961-1990 are assessed. The regions selected by the AGROSCENARI project are important from the local agricultural practises and are situated as follows: in the Northern Italy - Po valley and hilly area of Faenza; in Central part of Italy- Marche, Beneventano and Destra Sele, and in Sardinia Island - Oristano. A statistical downscaling technique applied to the ENSEMBLES global climate simulations, A1B scenario, is used to reach this objective. The method consists of a multivariate regression, based on Canonical Correlation Analysis, using as possible predictors mean sea level pressure, geopotential height at 500hPa and temperature at 850 hPa. The observational data set (predictands) for the selected regions is composed by a reconstruction of minimum, maximum temperature and precipitation daily data on a regular grid with a spatial resolution of 35 km, for 1951-2009 period (managed by the Meteorological and Climatological research unit for agriculture - Agricultural Research Council, CRA - CMA). First, a set-up of statistical model has been made using predictors from ERA40 reanalysis and the seasonal indices of temperature and precipitation from local scale, 1958-2002 period. Then, the statistical downscaling model has been applied to the predictors derived from the ENSEMBLES global climate models, A1B scenario, in order to obtain climate change scenario of temperature and precipitation at local scale, 2021-2050 period. The projections show that increases could be expected to occur under scenario conditions in all seasons, in both minimum and maximum temperature. The magnitude of changes is more intense during summer when the changes could reach values around 2°C for minimum and maximum temperature. In the case of precipitation, the pattern of changes is more complex, different from season to season and over the regions, a

  14. Modeling and Composing Scenario-Based Requirements with Aspects

    NASA Technical Reports Server (NTRS)

    Araujo, Joao; Whittle, Jon; Ki, Dae-Kyoo

    2004-01-01

    There has been significant recent interest, within the Aspect-Oriented Software Development (AOSD) community, in representing crosscutting concerns at various stages of the software lifecycle. However, most of these efforts have concentrated on the design and implementation phases. We focus in this paper on representing aspects during use case modeling. In particular, we focus on scenario-based requirements and show how to compose aspectual and non-aspectual scenarios so that they can be simulated as a whole. Non-aspectual scenarios are modeled as UML sequence diagram. Aspectual scenarios are modeled as Interaction Pattern Specifications (IPS). In order to simulate them, the scenarios are transformed into a set of executable state machines using an existing state machine synthesis algorithm. Previous work composed aspectual and non-aspectual scenarios at the sequence diagram level. In this paper, the composition is done at the state machine level.

  15. The scenario-based generalization of radiation therapy margins.

    PubMed

    Fredriksson, Albin; Bokrantz, Rasmus

    2016-03-07

    We give a scenario-based treatment plan optimization formulation that is equivalent to planning with geometric margins if the scenario doses are calculated using the static dose cloud approximation. If the scenario doses are instead calculated more accurately, then our formulation provides a novel robust planning method that overcomes many of the difficulties associated with previous scenario-based robust planning methods. In particular, our method protects only against uncertainties that can occur in practice, it gives a sharp dose fall-off outside high dose regions, and it avoids underdosage of the target in 'easy' scenarios. The method shares the benefits of the previous scenario-based robust planning methods over geometric margins for applications where the static dose cloud approximation is inaccurate, such as irradiation with few fields and irradiation with ion beams. These properties are demonstrated on a suite of phantom cases planned for treatment with scanned proton beams subject to systematic setup uncertainty.

  16. Using scenario planning in public health: anticipating alternative futures.

    PubMed

    Neiner, Jennifer A; Howze, Elizabeth H; Greaney, Mary L

    2004-01-01

    Scenario planning is a method for anticipating possible alternative futures. Used widely in business applications, it allows planners to anticipate problems, reevaluate assumptions, and reflect on consequences of those alternative futures. In this article, scenario planning is applied to public health, specifically to illustrate the four steps in scenario planning for public health using a health department's desire to address chronic disease prevention and control. An unhealthy diet and physical inactivity are considered to be key risk factors. The scenarios are presented in table format and are for illustration purposes only. Many other plausible scenarios could be constructed. Scenario planning allows stake-holders to define a desired, shared vision of the future, but more important, they can better prepare public health professionals to be successful in a constantly changing environment.

  17. Land-Use Scenarios: National-Scale Housing-Density ...

    EPA Pesticide Factsheets

    EPA announced the availability of the final report, Land-Use Scenarios: National-Scale Housing-Density Scenarios Consistent with Climate Change Storylines. This report describes the scenarios and models used to generate national-scale housing density scenarios for the conterminous US to the year 2100 as part of the Integrated Climate and Land Use Scenarios (ICLUS) project. The report was prepared by the Global Change Research Program (GCRP) in the National Center for Environmental Assessment (NCEA) of the Office of Research and Development (ORD) at the U.S. Environmental Protection Agency (EPA). The ICLUS report describes the methods used to develop land-use scenarios by decade from the year 2000 to 2100 that are consistent with these storylines.

  18. Modelling the response of shallow groundwater levels to combined climate and water-diversion scenarios in Beijing-Tianjin-Hebei Plain, China

    NASA Astrophysics Data System (ADS)

    Li, Xue; Ye, Si-Yuan; Wei, Ai-Hua; Zhou, Peng-Peng; Wang, Li-Heng

    2017-09-01

    A three-dimensional groundwater flow model was implemented to quantify the temporal variation of shallow groundwater levels in response to combined climate and water-diversion scenarios over the next 40 years (2011-2050) in Beijing-Tianjin-Hebei (Jing-Jin-Ji) Plain, China. Groundwater plays a key role in the water supply, but the Jing-Jin-Ji Plain is facing a water crisis. Groundwater levels have declined continuously over the last five decades (1961-2010) due to extensive pumping and climate change, which has resulted in decreased recharge. The implementation of the South-to-North Water Diversion Project (SNWDP) will provide an opportunity to restore the groundwater resources. The response of groundwater levels to combined climate and water-diversion scenarios has been quantified using a groundwater flow model. The impacts of climate change were based on the World Climate Research Programme's (WCRP's) Coupled Model Intercomparison Project phase 3 (CMIP3) multi-model dataset for future high (A2), medium (A1B), and low (B1) greenhouse gas scenarios; precipitation data from CMIP3 were applied in the model. The results show that climate change will slow the rate of decrease of the shallow groundwater levels under three climate-change scenarios over the next 40 years compared to the baseline scenario; however, the shallow groundwater levels will rise significantly (maximum of 6.71 m) when considering scenarios that combine climate change and restrictions on groundwater exploitation. Restrictions on groundwater exploitation for water resource management are imperative to control the decline of levels in the Jing-Jin-Ji area.

  19. Modelling the response of shallow groundwater levels to combined climate and water-diversion scenarios in Beijing-Tianjin-Hebei Plain, China

    NASA Astrophysics Data System (ADS)

    Li, Xue; Ye, Si-Yuan; Wei, Ai-Hua; Zhou, Peng-Peng; Wang, Li-Heng

    2017-03-01

    A three-dimensional groundwater flow model was implemented to quantify the temporal variation of shallow groundwater levels in response to combined climate and water-diversion scenarios over the next 40 years (2011-2050) in Beijing-Tianjin-Hebei (Jing-Jin-Ji) Plain, China. Groundwater plays a key role in the water supply, but the Jing-Jin-Ji Plain is facing a water crisis. Groundwater levels have declined continuously over the last five decades (1961-2010) due to extensive pumping and climate change, which has resulted in decreased recharge. The implementation of the South-to-North Water Diversion Project (SNWDP) will provide an opportunity to restore the groundwater resources. The response of groundwater levels to combined climate and water-diversion scenarios has been quantified using a groundwater flow model. The impacts of climate change were based on the World Climate Research Programme's (WCRP's) Coupled Model Intercomparison Project phase 3 (CMIP3) multi-model dataset for future high (A2), medium (A1B), and low (B1) greenhouse gas scenarios; precipitation data from CMIP3 were applied in the model. The results show that climate change will slow the rate of decrease of the shallow groundwater levels under three climate-change scenarios over the next 40 years compared to the baseline scenario; however, the shallow groundwater levels will rise significantly (maximum of 6.71 m) when considering scenarios that combine climate change and restrictions on groundwater exploitation. Restrictions on groundwater exploitation for water resource management are imperative to control the decline of levels in the Jing-Jin-Ji area.

  20. Intelligent scenario generation for simulation-based training

    NASA Technical Reports Server (NTRS)

    Loftin, R. Bowen; Wang, Lui; Baffes, Paul

    1989-01-01

    A training scenario generator object database was developed to serve as a general-purpose mechanism for constructing the context needed to define a simulation scenario. It is found that the ability to automate the development of the input parameters required to produce a challenging simulation scenario targeted at a specific trainee can greatly enhance the efficiency of intelligent training systems. The approach described was used successfully in the payload-assist module deploy/intelligent computer-aided training system.

  1. Propagation models for non line-of-sight scenarios

    NASA Astrophysics Data System (ADS)

    Tasu, A. S.; Anchidin, L.; Tamas, R.; Petrescu, T.

    2016-12-01

    The log-normal propagation model is usually applied for scenarios including a line-of-sight path. However, there are many cases that do not include such a propagation path, e.g. indoor transmission and disaster situations, when radio waves have to penetrate trough ruins. In this paper, we show that the log-normal model can also be applied for non line-of-sight transmission. Both indoor scenario and trough-ruins scenario, are investigated.

  2. Overview of the ARkStorm scenario

    USGS Publications Warehouse

    Porter, Keith; Wein, Anne; Alpers, Charles; Baez, Allan; Barnard, Patrick L.; Carter, James; Corsi, Alessandra; Costner, James; Cox, Dale; Das, Tapash; Dettinger, Mike; Done, James; Eadie, Charles; Eymann, Marcia; Ferris, Justin; Gunturi, Prasad; Hughes, Mimi; Jarrett, Robert; Johnson, Laurie; Le-Griffin, Hanh Dam; Mitchell, David; Morman, Suzette; Neiman, Paul; Olsen, Anna; Perry, Suzanne; Plumlee, Geoffrey; Ralph, Martin; Reynolds, David; Rose, Adam; Schaefer, Kathleen; Serakos, Julie; Siembieda, William; Stock, Jonathan; Strong, David; Wing, Ian Sue; Tang, Alex; Thomas, Pete; Topping, Ken; Wills, Chris; Jones, Lucile

    2011-01-01

    The U.S. Geological Survey, Multi Hazards Demonstration Project (MHDP) uses hazards science to improve resiliency of communities to natural disasters including earthquakes, tsunamis, wildfires, landslides, floods and coastal erosion. The project engages emergency planners, businesses, universities, government agencies, and others in preparing for major natural disasters. The project also helps to set research goals and provides decision-making information for loss reduction and improved resiliency. The first public product of the MHDP was the ShakeOut Earthquake Scenario published in May 2008. This detailed depiction of a hypothetical magnitude 7.8 earthquake on the San Andreas Fault in southern California served as the centerpiece of the largest earthquake drill in United States history, involving over 5,000 emergency responders and the participation of over 5.5 million citizens. This document summarizes the next major public project for MHDP, a winter storm scenario called ARkStorm (for Atmospheric River 1,000). Experts have designed a large, scientifically realistic meteorological event followed by an examination of the secondary hazards (for example, landslides and flooding), physical damages to the built environment, and social and economic consequences. The hypothetical storm depicted here would strike the U.S. West Coast and be similar to the intense California winter storms of 1861 and 1862 that left the central valley of California impassible. The storm is estimated to produce precipitation that in many places exceeds levels only experienced on average once every 500 to 1,000 years. Extensive flooding results. In many cases flooding overwhelms the state's flood-protection system, which is typically designed to resist 100- to 200-year runoffs. The Central Valley experiences hypothetical flooding 300 miles long and 20 or more miles wide. Serious flooding also occurs in Orange County, Los Angeles County, San Diego, the San Francisco Bay area, and other

  3. Computational studies of origins of life scenarios

    NASA Astrophysics Data System (ADS)

    Mathew, Damien Cherian

    Understanding the origins of life on Earth is one of the most intriguing problems facing science today. In the research presented here, we apply computational methods to explore origins of life scenarios. In particular, we focus on the origins of the genetic code and the intersection between geochemistry and a primordial "biochemistry" in which mononucleotides could form short oligoucleotide chains. We also apply quantum chemical methods to a modern biochemical reaction, the charging of tRNA by an aminoacyl-tRNA synthetase, in order to shed light on the possible chemistry one may want to consider in problems relating to the origins of life. The question of how codons came to be associated with specific amino acids in the present form of the genetic code is one fundamental part of gaining insight into the origins of life. Carl Woese and coworkers designed a series of experiments to test associations between amino acids and nucleobases that may have played a role in establishing the genetic code. Through these experiments it was found that a property of amino acids called the polar requirement (PR) is correlated to the organization of the codon table. No other property of amino acids has been found that correlates with the codon table as well as PR, indicating that PR is uniquely related to the modern genetic code. Using molecular dynamics simulations of amino acids in solutions of water and dimethylpyridine used to experimentally measure PR, we show that variations in the partitioning between the two phases as described by radial distribution functions correlate well with the measured PRs. Partition coefficients based on probability densities of the amino acids in each phase have the linear behavior with base concentration as suggested by the PR experiments. We also investigate the possible roles of inorganic mineral surfaces in catalysis and stabilization of reactions essential for early forms of replicating systems that could have evolved into biochemical

  4. Non-standard structure formation scenarios

    NASA Astrophysics Data System (ADS)

    Knebe, Alexander; Little, Brett; Islam, Ranty; Devriendt, Julien; Mahmood, Asim; Silk, Joe

    2003-04-01

    Observations on galactic scales seem to be in contradiction with recent high resolution N-body simulations. This so-called cold dark matter (CDM) crisis has been addressed in several ways, ranging from a change in fundamental physics by introducing self-interacting cold dark matter particles to a tuning of complex astrophysical processes such as global and/or local feedback. All these efforts attempt to soften density profiles and reduce the abundance of satellites in simulated galaxy halos. In this contribution we are exploring the differences between a Warm Dark Matter model and a CDM model where the power on a certain scale is reduced by introducing a narrow negative feature (`dip'). This dip is placed in a way so as to mimic the loss of power in the WDM model: both models have the same integrated power out to the scale where the power of the Dip model rises to the level of the unperturbed CDM spectrum again. Using N-body simulations we show that that the new Dip model appears to be a viable alternative to WDM while being based on different physics: where WDM requires the introduction of a new particle species the Dip stems from anon-standard inflationary period. If we are looking for an alternative to the currently challenged standard ΛCDM structure formation scenario, neither the ΛWDM nor the new Dip model can be ruled out with respect to the analysis presented in this contribution. They both make very similar predictions and the degeneracy between them can only be broken with observations yet to come.

  5. Toward Interactive Scenario Analysis and Exploration

    SciTech Connect

    Gayle, Thomas R.; Summers, Kenneth Lee; Jungels, John; Oppel III, Fred J.

    2015-01-01

    As Modeling and Simulation (M&S) tools have matured, their applicability and importance have increased across many national security challenges. In particular, they provide a way to test how something may behave without the need to do real world testing. However, current and future changes across several factors including capabilities, policy, and funding are driving a need for rapid response or evaluation in ways that many M&S tools cannot address. Issues around large data, computational requirements, delivery mechanisms, and analyst involvement already exist and pose significant challenges. Furthermore, rising expectations, rising input complexity, and increasing depth of analysis will only increase the difficulty of these challenges. In this study we examine whether innovations in M&S software coupled with advances in ''cloud'' computing and ''big-data'' methodologies can overcome many of these challenges. In particular, we propose a simple, horizontally-scalable distributed computing environment that could provide the foundation (i.e. ''cloud'') for next-generation M&S-based applications based on the notion of ''parallel multi-simulation''. In our context, the goal of parallel multi- simulation is to consider as many simultaneous paths of execution as possible. Therefore, with sufficient resources, the complexity is dominated by the cost of single scenario runs as opposed to the number of runs required. We show the feasibility of this architecture through a stable prototype implementation coupled with the Umbra Simulation Framework [6]. Finally, we highlight the utility through multiple novel analysis tools and by showing the performance improvement compared to existing tools.

  6. Effective Scenarios for Exploring Asteroid Surfaces

    NASA Astrophysics Data System (ADS)

    Clark, Pamela E.; Clark, C.; Weisbin, C.

    2010-10-01

    In response to the proposal that asteroids be the next targets for exploration, we attempt to develop scenarios for exploring previously mapped asteroid 433 Eros, harnessing our recent experience gained planning such activity for return to the lunar surface. The challenges faced in planning Apollo led to the development of a baseline methodology for extraterrestrial field science. What `lessons learned’ can be applied for asteroids? Effective reconnaissance (advanced mapping at <0.5 m, photos with plotted routes as in-field reference maps), training/simulating/planning (highly interactive abundant field time for extended crew), and documentation (hands-free audio and visual systematic description) procedures are still valid. The use of Constant Scale Natural Boundary rather than standard projection maps eases the challenge of navigating and interpreting a highly irregular object. Lunar and asteroid surfaces are dominated by bombardment and space radiation/dust/charged particle/regolith interactions, with similar implications for sampling. Asteroid work stations are selected on the basis of impact-induced exposure of `outcrops’ from prominent ridges (e.g., Himeros, the noses) potentially representing underlying material, supplemented by sampling of areas of especially thin or deep regolith (ponds). Unlike the Moon, an asteroid lacks sufficient gravity and most likely the necessary stability to support `normal’ driving or walking. In fact, the crew delivery vehicle might not even be `tetherable’ and would most likely `station keep’ to maintain a position. The most convenient local mobility mechanism for astronauts/robots would be `hand over hand’ above the surface at a field station supplemented by a `tetherless’ (small rocket-pack) control system for changing station or return to vehicle. Thus, we assume similar mobility constraints (meters to hundreds of meters at a local station, kilometers between stations) as those used for Apollo. We also assume

  7. Turbulence mitigation methods for sea scenarios

    NASA Astrophysics Data System (ADS)

    Dijk, Judith; Schutte, Klamer; Nieuwenhuizen, Robert P. J.

    2016-10-01

    Visual and infrared imagery is degraded by turbulence caused by atmospheric conditions. Because the degradation gets worse for longer distances, turbulence especially hampers long range observation. At sea this turbulence affects classification and identification of ships and other objects. State of the art software based processing algorithms assuming a static background assumption will fail in such conditions because of the non-static sea background. Therefore, we propose an adapted processing chain aiming to provide optimal turbulence correction for ships seen in the camera view. First we propose to use standard object detection and tracking methods for an indication of the location of the ship. Subsequently, image registration is performed within the ship's region of interest, covering only the ship of interest. After this region of interest registration, standard turbulence mitigation software can be applied to the region of interest. For ships with other movement than translation only we propose a two-step motion estimation using local optical flow. In this paper we show results of this processing chain for sea scenarios using our TNO turbulence mitigation method. Ship data is processed using the algorithm proposed above and the results are analyzed by both human observation and by image analysis. The improvement of the imagery is qualitatively shown by examining details which cannot be seen without processing and can be seen with processing. Quantitatively, the improvement is related to the energy per spatial frequency in the original and processed images and the signal to noise improvement. This provides a model for the improvement of the results, and is related to the improvement of the classification and identification range. The results show that with this novel approach the classification and identification range of ships is improved.

  8. Radiation Protection for Lunar Mission Scenarios

    NASA Technical Reports Server (NTRS)

    Clowdsley, Martha S.; Nealy, John E.; Wilson, John W.; Anderson, Brooke M.; Anderson, Mark S.; Krizan, Shawn A.

    2005-01-01

    Preliminary analyses of shielding requirements to protect astronauts from the harmful effects of radiation on both short-term and long-term lunar missions have been performed. Shielding needs for both solar particle events (SPEs) and galactic cosmic ray (GCR) exposure are discussed for transit vehicles and surface habitats. This work was performed under the aegis of two NASA initiatives. The first study was an architecture trade study led by Langley Research Center (LaRC) in which a broad range of vehicle types and mission scenarios were compared. The radiation analysis for this study primarily focused on the additional shielding mass required to protect astronauts from the rare occurrence of a large SPE. The second study, led by Johnson Space Center (JSC), involved the design of lunar habitats. Researchers at LaRC were asked to evaluate the changes to mission architecture that would be needed if the surface stay were lengthened from a shorter mission duration of 30 to 90 days to a longer stay of 500 days. Here, the primary radiation concern was GCR exposure. The methods used for these studies as well as the resulting shielding recommendations are discussed. Recommendations are also made for more detailed analyses to minimize shielding mass, once preliminary vehicle and habitat designs have been completed. Here, methodologies are mapped out and available radiation analysis tools are described. Since, as yet, no dosimetric limits have been adopted for missions beyond low earth orbit (LEO), radiation exposures are compared to LEO limits. Uncertainties associated with the LEO career effective dose limits and the effects of lowering these limits on shielding mass are also discussed.

  9. Heuristic scenario builder for power system operator training

    SciTech Connect

    Irisarri, G.; Rafian, M. ); Miller, B.N. ); Dobrowolski, E.J. )

    1992-05-01

    The Heuristic Scenario Builder (HSB), a knowledge-based training scenario builder for the EPRI Operator Training Simulator (OTS), is described in this paper. Expert systems and heuristic searches are used in the HSB to find training scenarios that closely fit trainee profiles and that address particular training requirements. Expert knowledge obtained from instructors and other operations personnel is used throughout the HSB to determine the scenarios. The HSB is an integral part of the OTS and is currently in operation at Philadelphia Electric's OTS installation.

  10. Traffic scenario generation technique for piloted simulation studies

    NASA Technical Reports Server (NTRS)

    Williams, David H.; Wells, Douglas C.

    1985-01-01

    Piloted simulation studies of cockpit traffic display concepts require the development of representative traffic scenarios. With the exception of specific aircraft interaction issues, most research questions can be addressed using traffic scenarios consisting of prerecorded aircraft movements merged together to form a desired traffic pattern. Prerecorded traffic scenarios have distinct research advantages, allowing control of traffic encounters with repeatability of scenarios between different test subjects. A technique is described for generation of prerecorded jet transport traffic scenarios suitable for use in piloted simulation studies. Individual flight profiles for the aircraft in the scenario are created interactively with a computer program designed specifically for this purpose. The profiles are then time-correlated and merged into a complete scenario. This technique was used to create traffic scenarios for the Denver, Colorado area with operations centered at Stapleton International Airport. Traffic scenarios for other areas may also be created using this technique, with appropriate modifications made to the navigation fix locations contained in the flight profile generation program.

  11. Effects of exemplar scenarios on public preferences for energy futures using the my2050 scenario-building tool

    NASA Astrophysics Data System (ADS)

    Demski, Christina; Spence, Alexa; Pidgeon, Nick

    2017-03-01

    Understanding which energy future configurations provide publicly acceptable levels of energy security, affordability, and environmental protection is critical for institutional decision-making. However, little is known about how scenarios influence energy preferences. Here we present nationally representative UK data on public preferences for energy futures using the my2050 scenario-building tool that encourages engagement with the holistic complexities of system change. Engagement with the tool strengthened existing preferences for renewable energy and intentions to take personal action. Importantly, patterns of energy preferences were influenced by exemplar scenarios, which served as reference points that anchored choices. Carbon capture and storage, nuclear power, biofuels, and changes to heating and travel were particularly impacted by scenarios indicating uncertainty and ambivalence regarding these options. Scenarios (and scenario-building tools) are valuable for engaging citizens about future energy systems. However, care is required in their design and interpretation to reach robust conclusions about underlying preferences and acceptance.

  12. Future possible crop yield scenarios under multiple SSP and RCP scenarios.

    NASA Astrophysics Data System (ADS)

    Sakurai, G.; Yokozawa, M.; Nishimori, M.; Okada, M.

    2016-12-01

    Understanding the effect of future climate change on global crop yields is one of the most important tasks for global food security. Future crop yields would be influenced by climatic factors such as the changes of temperature, precipitation and atmospheric carbon dioxide concentration. On the other hand, the effect of the changes of agricultural technologies such as crop varieties, pesticide and fertilizer input on crop yields have large uncertainty. However, not much is available on the contribution ratio of each factor under the future climate change scenario. We estimated the future global yields of four major crops (maize, soybean, rice and wheat) under three Shared Socio Economic Pathways (SSPs) and four Representative Concentration Pathways (RCPs). For this purpose, firstly, we estimated a parameter of a process based model (PRYSBI2) using a Bayesian method for each 1.125 degree spatial grid. The model parameter is relevant to the agricultural technology (we call "technological parameter" here after). Then, we analyzed the relationship between the values of technological parameter and GDP values. We found that the estimated values of the technological parameter were positively correlated with the GDP. Using the estimated relationship, we predicted future crop yield during 2020 and 2100 under SSP1, SSP2 and SSP3 scenarios and RCP 2.6, 4.5, 6.0 and 8.5. The estimated crop yields were different among SSP scenarios. However, we found that the yield difference attributable to SSPs were smaller than those attributable to CO2 fertilization effects and climate change. Particularly, the estimated effect of the change of atmospheric carbon dioxide concentration on global yields was more than four times larger than that of GDP for C3 crops.

  13. Adaption strategies to the effect of climate change on a coastal area in Northwest Germany with different land management scenarios

    NASA Astrophysics Data System (ADS)

    Graeff, Thomas; Krause, Stefan; Maier, Martin; Oswald, Sascha

    2015-04-01

    used as a third landuse scenario. A hydrological model that couples surface water and groundwater interactions is used. Several climate scenarios based on the IPCC emission scenarios are applied (A1B, A2 and B1 are used to cover an increase of future temperature between 1 and 3.5 K) in combination with three different heights of sea water level increase. Furthermore, the effectivity of the scenarios in respect to ecosystem services and economic efficiency are calculated. The business as usual scenario is able to guaranty the current farming strategy by coastal defences and prevention of inundation, but the cost intensive pumping rates increase. Areas with subsurface preferential pathways for groundwater to the land surface have the potential to be affected by salinization of groundwater, soil and drainages, without coastal defences to be able to prevent that. The large polder systems are able to buffer the increasing precipitation volumes to the price of losing 20 percent of the agriculture area and locally the creation of a completely different landscape. The polders are used effectively to store freshwater in summer periods and can actually also be used to prevent salinization. The stakeholder scenario with small distributed polders have a comparable effect with the benefit of preserving the original landscape and higher acceptance by the local residents, but with higher cost for more elaborate water resources management and maintenance.

  14. Modelling soil organic carbon stocks along topographic transects under climate change scenarios using CarboSOIL

    NASA Astrophysics Data System (ADS)

    Kotb Abd-Elmabod, Sameh; Muñoz-Rojas, Miriam; Jordán, Antonio; Anaya-Romero, María; de la Rosa, Diego

    2014-05-01

    CarboSOIL is a land evaluation model for soil organic carbon (SOC) accounting under global change scenarios (Muñoz-Rojas et al., 2013a; 2013b) and is a new component of the MicroLEIS Decision Support System. MicroLEIS is a tool for decision-makers dealing with specific agro-ecological problems as, for example, soil contamination risks (Abd-Elmabod et al., 2010; Abd-Elmabod et al., 2012)which has been designed as a knowledge-based approach incorporating a set of interlinked data bases. Global change and land use changes in recent decades have caused relevant impacts in vegetation carbon stocks (Muñoz-Rojas et al., 2011) and soil organic carbon stocks, especially in sensible areas as the Mediterranean region (Muñoz-Rojas et al., 2012a; 2012b). This study aims to investigate the influence of topography, climate, land use and soil factors on SOC stocks by the application of CarboSOIL in a representative area of the Mediterranean region (Seville, Spain). Two topographic transects (S-N and W-E oriented) were considered, including 63 points separated 4 km each. These points are associated to 41 soil profiles extracted from the SDBm soil data base (De la Rosa et al., 2001) and climatic information (average minimum temperature, average maximum temperature and average rainfall per month) extracted from raster data bases (Andalusian Environmental Information Network, REDIAM). CarboSOIL has been applied along topographic transects at different soil depths and under different climate change scenarios. Climate scenarios have been calculated according to the global climate model (CNRMCM3) by extracting spatial climate data under IPCC A1B scenario for the current period (average data from 1960-2000), 2040, 2070 and 2100. In the current scenario, results show that the highest SOC stock values located on Typic Haploxeralfs under olive groves for soil sections 0-25 cm and for 25-50 cm, but the highest values were determined on fruit-cropped Rendolic Xerothent in the 50-75cm

  15. Predicting Monsoonal-Driven Stream Discharge and Sediment Yield in Himalaya Mountain Basins with Changing Climate and Deforestation

    NASA Astrophysics Data System (ADS)

    Neupane, R. P.; White, J. D.

    2014-12-01

    Short and long term effects of site water availability impacts the spectrum of management outcomes including landslide risk, hydropower generation, and sustainable agriculture in mountain systems heavily influenced by climate and land use changes. Climate change and land use may predominantly affect the hydrologic cycle of mountain basins as soil precipitation interception is affected by land cover. Using the Soil and Water Assessment Tool, we estimated stream discharge and sediment yield associated with climate and land use changes for two Himalaya basins located at eastern and western margins of Nepal that included drainages of the Tamor and Seti Rivers. Future climate change was modeled using average output of temperature and precipitation changes derived from Special Report on Emission Scenarios (B1, A1B & A2) of 16 global circulation models for 2080 as meteorological inputs into SWAT. Land use change was modeled spatially and included 1) deforestation, 2) expansion of agricultural land, and 3) increased human settlement that were produced by considering current land use with projected changes associated with viability of elevation and slope characteristics of the basins capable of supporting different land use types. We found higher annual stream discharge in all GCM-derived scenarios compared to the baseline with maximum increases of 13 and 8% in SRES-A2 and SRES-A1B for the Tamor and Seti basins, respectively. With 7% of original forest land removed, sediment yield for Tamor basin was estimated to be 65% higher, but increased to 124% for the SRES-B1 scenario. For the Seti basin, 4% deforestation yielded 33% more sediment for the SRES-A1B scenario. Our results indicated that combined effects of future, intensified monsoon rainfall with deforestation lead to dramatic potential for increased stream discharge and sediment yield as rainfall on steep slopes with thin exposed soils increases surface runoff and soil erosion in the Himalayas. This effect appears to

  16. Scenarios in society, society in scenarios: toward a social scientific analysis of storyline-driven environmental modeling

    NASA Astrophysics Data System (ADS)

    Garb, Yaakov; Pulver, Simone; Van Deveer, Stacy D.

    2008-10-01

    Scenario analysis, an approach to thinking about alternative futures based on storyline-driven modeling, has become increasingly common and important in attempts to understand and respond to the impacts of human activities on natural systems at a variety of scales. The construction of scenarios is a fundamentally social activity, yet social scientific perspectives have rarely been brought to bear on it. Indeed, there is a growing imbalance between the increasing technical sophistication of the modeling elements of scenarios and the continued simplicity of our understanding of the social origins, linkages, and implications of the narratives to which they are coupled. Drawing on conceptual and methodological tools from science and technology studies, sociology and political science, we offer an overview of what a social scientific analysis of scenarios might include. In particular, we explore both how scenarios intervene in social microscale and macroscale contexts and how aspects of such contexts are embedded in scenarios, often implicitly. Analyzing the social 'work' of scenarios (i) can enhance the understanding of scenario developers and modeling practitioners of the knowledge production processes in which they participate and (ii) can improve the utility of scenario products as decision-support tools to actual, rather than imagined, decision-makers.

  17. Analysis of five simulated straw harvest scenarios

    SciTech Connect

    Sokhansanj, Shahabaddine; Turhollow Jr, Anthony F; Stephen, Jamie; Stumborg, Mark; Fenton, James; Mani, Sudhagar

    2008-01-01

    Almost 36 million tonnes (t) of cereal grains are harvested annually on more than 16 million hectares (ha) in Canada. The net straw production varies year by year depending upon weather patterns, crop fertility, soil conservation measures, harvest method, and plant variety. The net yield of straw, after discounting for soil conservation, averages approximately 2.5 dry (d)t ha-1. Efficient equipment is needed to collect and package the material as a feedstock for industrial applications. This paper investigates the costs, energy input, and emissions from power equipment used for harvesting straw. Five scenarios were investigated: (1) large square bales, (2) round bales, (3) large compacted stacks (loafs), (4) dried chops, and (5) wet chops. The baled or loafed biomass is stacked next to the farm. Dry chop is collected in a large pile and wet chop is ensiled. The baling and stacking cost was $21.47 dt-1 (dry tonne), with little difference between round and large square baling. Loafing was the cheapest option at $17.08 dt-1. Dry chop and piling was $23.90 dt-1 and wet chop followed by ensiling was $59.75 dt-1. A significant portion of the wet chop cost was in ensiling. Energy input and emissions were proportional to the costs for each system, except for loafing, which required more energy input than the baling systems. As a fraction of the energy content of biomass (roughly 16 GJ dt-1), the energy input ranged from 1.2% for baling to 3.2% for ensiling. Emissions from the power equipment ranged from 20.3 kg CO2e dt-1 to more than 40 kg CO2e dt-1. A sensitivity analysis on the effect of yield on collection costs showed that a 33% increase in yield reduced the cost by 20%. Similarly a sensitivity analysis on weather conditions showed that a 10oC cooler climate extended the harvest period by 5-10 days whereas a 10oC warmer climate shortened the harvest period by 2-3 days.

  18. ImmunoScenarios: A Game for the Immune System.

    ERIC Educational Resources Information Center

    Taylor, Mark F.; Jackson, Sally W.

    1996-01-01

    Describes a board game, ImmunoScenarios, which was developed to reinforce the ideas about the immune system discussed in lecture classes. Emphasizes important characteristics of the body's specific defense system including specificity, cooperation among various cells, and memory. Includes directions for playing, student handouts, and scenarios.…

  19. Visualization of Learning Scenarios with UML4LD

    ERIC Educational Resources Information Center

    Laforcade, Pierre

    2007-01-01

    Present Educational Modelling Languages are used to formally specify abstract learning scenarios in a machine-interpretable format. Current tooling does not provide teachers/designers with some graphical facilities to help them in reusing existent scenarios. They need human-readable representations. This paper discusses the UML4LD experimental…

  20. 10 CFR 63.322 - Human intrusion scenario.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 2 2011-01-01 2011-01-01 false Human intrusion scenario. 63.322 Section 63.322 Energy... REPOSITORY AT YUCCA MOUNTAIN, NEVADA Postclosure Public Health and Environmental Standards Human Intrusion Standard § 63.322 Human intrusion scenario. For the purposes of the analysis of human intrusion, DOE...

  1. 10 CFR 63.322 - Human intrusion scenario.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Human intrusion scenario. 63.322 Section 63.322 Energy... REPOSITORY AT YUCCA MOUNTAIN, NEVADA Postclosure Public Health and Environmental Standards Human Intrusion Standard § 63.322 Human intrusion scenario. For the purposes of the analysis of human intrusion, DOE...

  2. Child-Specific Exposure Scenarios Examples (Final Report)

    EPA Science Inventory

    EPA announced the availability of the final report, Child-Specific Exposure Scenarios Examples. This report is intended to be a companion document to the Exposure Factors Handbook (U.S. EPA 2011). The example scenarios were compiled from questions and inquiries r...

  3. The Future of Florida: Four Scenarios for the Sunshine State.

    ERIC Educational Resources Information Center

    Bezold, Clement and Olson, Robert

    1983-01-01

    Looking at four different scenarios for Florida's future--continued growth, new federalism, depression/hurricane, and third wave--can help clarify goals for the future. Each scenario's effect on such key areas as energy use, transportation, water, and education is considered. (IS)

  4. Child-Specific Exposure Scenarios Examples (Final Report)

    EPA Science Inventory

    EPA announced the availability of the final report, Child-Specific Exposure Scenarios Examples. This report is intended to be a companion document to the Exposure Factors Handbook (U.S. EPA 2011). The example scenarios were compiled from questions and inquiries r...

  5. Application Scenarios for Nonstandard Log-Linear Models

    ERIC Educational Resources Information Center

    Mair, Patrick; von Eye, Alexander

    2007-01-01

    In this article, the authors have 2 aims. First, hierarchical, nonhierarchical, and nonstandard log-linear models are defined. Second, application scenarios are presented for nonhierarchical and nonstandard models, with illustrations of where these scenarios can occur. Parameters can be interpreted in regard to their formal meaning and in regard…

  6. 10 CFR 63.322 - Human intrusion scenario.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 2 2014-01-01 2014-01-01 false Human intrusion scenario. 63.322 Section 63.322 Energy... REPOSITORY AT YUCCA MOUNTAIN, NEVADA Postclosure Public Health and Environmental Standards Human Intrusion Standard § 63.322 Human intrusion scenario. For the purposes of the analysis of human intrusion, DOE must...

  7. 10 CFR 63.322 - Human intrusion scenario.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 2 2012-01-01 2012-01-01 false Human intrusion scenario. 63.322 Section 63.322 Energy... REPOSITORY AT YUCCA MOUNTAIN, NEVADA Postclosure Public Health and Environmental Standards Human Intrusion Standard § 63.322 Human intrusion scenario. For the purposes of the analysis of human intrusion, DOE must...

  8. 10 CFR 63.322 - Human intrusion scenario.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 2 2013-01-01 2013-01-01 false Human intrusion scenario. 63.322 Section 63.322 Energy... REPOSITORY AT YUCCA MOUNTAIN, NEVADA Postclosure Public Health and Environmental Standards Human Intrusion Standard § 63.322 Human intrusion scenario. For the purposes of the analysis of human intrusion, DOE must...

  9. Alternative Needs Planning Methods and the Scenario Approach

    DTIC Science & Technology

    1980-05-23

    that can be used as aids. Consideration will be given to a multidimensional technique for catagorization described by Ducot and Lubben*. In addition...number of such rudimentary scenarios. It is anticipated that five or six might be identified. * Ducot , C. and Lubben, G. J., "A Typology for Scenarios

  10. Online Scenarios for Teaching Internet Ethics to Teens.

    ERIC Educational Resources Information Center

    Jacobson, Frances F.

    2001-01-01

    At University Laboratory High School, ethics lessons are integrated into the required eight-grade computer literacy course. Six messages are posted online, each containing an ethical scenario. Students add their opinions to each scenario's thread, read each other's postings, and respond to at least one student follow-up message within each topic.…

  11. Decision Driven Scenario Planning for Process-Level Interventions

    ERIC Educational Resources Information Center

    Chemarck, Thomas J.; Payne, Tiffani D.

    2005-01-01

    This article builds on previous work that classified types of scenario planning as effective or relevant for particular situations, by adding consideration for levels within the organization. In addition, the argument is built for using a particular form of scenarios to anticipate or explore process level problems and outcomes. The problem of…

  12. Predictive RANS simulations via Bayesian Model-Scenario Averaging

    NASA Astrophysics Data System (ADS)

    Edeling, W. N.; Cinnella, P.; Dwight, R. P.

    2014-10-01

    The turbulence closure model is the dominant source of error in most Reynolds-Averaged Navier-Stokes simulations, yet no reliable estimators for this error component currently exist. Here we develop a stochastic, a posteriori error estimate, calibrated to specific classes of flow. It is based on variability in model closure coefficients across multiple flow scenarios, for multiple closure models. The variability is estimated using Bayesian calibration against experimental data for each scenario, and Bayesian Model-Scenario Averaging (BMSA) is used to collate the resulting posteriors, to obtain a stochastic estimate of a Quantity of Interest (QoI) in an unmeasured (prediction) scenario. The scenario probabilities in BMSA are chosen using a sensor which automatically weights those scenarios in the calibration set which are similar to the prediction scenario. The methodology is applied to the class of turbulent boundary-layers subject to various pressure gradients. For all considered prediction scenarios the standard-deviation of the stochastic estimate is consistent with the measurement ground truth. Furthermore, the mean of the estimate is more consistently accurate than the individual model predictions.

  13. Assessing Threat Detection Scenarios through Hypothesis Generation and Testing

    DTIC Science & Technology

    2015-12-01

    Dog Day scenario .............................................................................................................. 9...Figure 1. Rankings of priority threats identified in the Dog Day scenario ............................... 9 Figure 2. Rankings of priority...potential threats (e.g., a statement indicating that bomb sniffing dogs kept returning to a specific location); this allowed for more certainty in

  14. Student Experience of a Scenario-Centred Curriculum

    ERIC Educational Resources Information Center

    Bell, Sarah; Galilea, Patricia; Tolouei, Reza

    2010-01-01

    In 2006 UCL implemented new scenario-centred degree programmes in Civil and Environmental Engineering. The new curriculum can be characterised as a hybrid of problem-based, project-based and traditional approaches to learning. Four times a year students work in teams for one week on a scenario which aims to integrate learning from lecture and…

  15. ImmunoScenarios: A Game for the Immune System.

    ERIC Educational Resources Information Center

    Taylor, Mark F.; Jackson, Sally W.

    1996-01-01

    Describes a board game, ImmunoScenarios, which was developed to reinforce the ideas about the immune system discussed in lecture classes. Emphasizes important characteristics of the body's specific defense system including specificity, cooperation among various cells, and memory. Includes directions for playing, student handouts, and scenarios.…

  16. Scenario Based E-Learning in Electrical Engineering Education

    ERIC Educational Resources Information Center

    Tambunan, Hamonangan; Dalimunte, Amirhud; Silitonga, Marsangkap

    2017-01-01

    The scenario based e-learning in Electrical Engineering Education Learning (EEEL) was developed by covering the scope and characteristics of all subjects and the competence unit of graduates in the field of pedagogy, professional, social and personality, with url addresed http://jpte-ft-unimed.edu20.org. The scenario incorporates the concept of…

  17. Application Scenarios for Nonstandard Log-Linear Models

    ERIC Educational Resources Information Center

    Mair, Patrick; von Eye, Alexander

    2007-01-01

    In this article, the authors have 2 aims. First, hierarchical, nonhierarchical, and nonstandard log-linear models are defined. Second, application scenarios are presented for nonhierarchical and nonstandard models, with illustrations of where these scenarios can occur. Parameters can be interpreted in regard to their formal meaning and in regard…

  18. A climate-change scenario for the Columbia River Basin.

    Treesearch

    Sue A. Ferguson

    1997-01-01

    This work describes the method used to generate a climate-change scenario for the Columbia River basin. The scenario considers climate patterns that may change if the atmospheric concentration of carbon dioxide (C02), or its greenhouse gas equivalent, were to double over pre-Industrial Revolution values. Given the current rate of increase in...

  19. Child-Specific Exposure Scenarios Examples (Final Report)

    EPA Science Inventory

    The Child-Specific Exposure Scenarios Examples (Final Report) is intended to be a companion document to the Exposure Factors Handbook (U.S. EPA 2011). The example scenarios were compiled from questions and inquiries received from users of the Exposure Factors Handbo...

  20. Predictive RANS simulations via Bayesian Model-Scenario Averaging

    SciTech Connect

    Edeling, W.N.; Cinnella, P.; Dwight, R.P.

    2014-10-15

    The turbulence closure model is the dominant source of error in most Reynolds-Averaged Navier–Stokes simulations, yet no reliable estimators for this error component currently exist. Here we develop a stochastic, a posteriori error estimate, calibrated to specific classes of flow. It is based on variability in model closure coefficients across multiple flow scenarios, for multiple closure models. The variability is estimated using Bayesian calibration against experimental data for each scenario, and Bayesian Model-Scenario Averaging (BMSA) is used to collate the resulting posteriors, to obtain a stochastic estimate of a Quantity of Interest (QoI) in an unmeasured (prediction) scenario. The scenario probabilities in BMSA are chosen using a sensor which automatically weights those scenarios in the calibration set which are similar to the prediction scenario. The methodology is applied to the class of turbulent boundary-layers subject to various pressure gradients. For all considered prediction scenarios the standard-deviation of the stochastic estimate is consistent with the measurement ground truth. Furthermore, the mean of the estimate is more consistently accurate than the individual model predictions.

  1. New Methods for Crafting Locally Decision-Relevant Scenarios

    NASA Astrophysics Data System (ADS)

    Lempert, R. J.

    2015-12-01

    Scenarios can play an important role in helping decision makers to imagine future worlds, both good and bad, different than the one with which we are familiar and to take concrete steps now to address the risks generated by climate change. At their best, scenarios can effectively represent deep uncertainty; integrate over multiple domains; and enable parties with different expectation and values to expand the range of futures they consider, to see the world from different points of view, and to grapple seriously with the potential implications of surprising or inconvenient futures. These attributes of scenario processes can prove crucial in helping craft effective responses to climate change. But traditional scenario methods can also fail to overcome difficulties related to choosing, communicating, and using scenarios to identify, evaluate, and reach consensus on appropriate policies. Such challenges can limit scenario's impact in broad public discourse. This talk will demonstrate how new decision support approaches can employ new quantitative tools that allow scenarios to emerge from a process of deliberation with analysis among stakeholders, rather than serve as inputs to it, thereby increasing the impacts of scenarios on decision making. This talk will demonstrate these methods in the design of a decision support tool to help residents of low lying coastal cities grapple with the long-term risks of sea level rise. In particular, this talk will show how information from the IPCC SSP's can be combined with local information to provide a rich set of locally decision-relevant information.

  2. Student Experience of a Scenario-Centred Curriculum

    ERIC Educational Resources Information Center

    Bell, Sarah; Galilea, Patricia; Tolouei, Reza

    2010-01-01

    In 2006 UCL implemented new scenario-centred degree programmes in Civil and Environmental Engineering. The new curriculum can be characterised as a hybrid of problem-based, project-based and traditional approaches to learning. Four times a year students work in teams for one week on a scenario which aims to integrate learning from lecture and…

  3. Summary of student scenarios: 2020 Vision project, fiscal year 1997

    SciTech Connect

    Gordon, K.W.; Munoz, A.; Scott, K.P.; Rinne, R.

    1997-11-01

    The Strategic Issues Thinking: 2020 Vision project introduces students and teaches to national security issues through the techniques of scenario building, and engages them in an interactive process of creating scenarios relevant to the Department of Energy, Defense Programs (DOE/DP). Starting with the world as it is today, teams of students develop a series of scenarios on international developments over the next 25 years under various circumstances. This report identifies recurrent themes in the student`s scenarios, lists creative ways the students presented their scenarios, compares and contrasts the program`s FY97 results with FY96 results, identifies the benefits of the program, and offers a glimpse of Sandia`s future plans for the 2020 Vision project.

  4. Shipping container response to three severe railway accident scenarios

    SciTech Connect

    Mok, G.C.; Fischer, L.E.; Murty, S.S.; Witte, M.C.

    1998-04-01

    The probability of damage and the potential resulting hazards are analyzed for a representative rail shipping container for three severe rail accident scenarios. The scenarios are: (1) the rupture of closure bolts and resulting opening of closure lid due to a severe impact, (2) the puncture of container by an impacting rail-car coupler, and (3) the yielding of container due to side impact on a rigid uneven surface. The analysis results indicate that scenario 2 is a physically unreasonable event while the probabilities of a significant loss of containment in scenarios 1 and 3 are extremely small. Before assessing the potential risk for the last two scenarios, the uncertainties in predicting complex phenomena for rare, high- consequence hazards needs to be addressed using a rigorous methodology.

  5. Innovation Design of Persimmon Processing Equipment Driven by Future Scenarios

    NASA Astrophysics Data System (ADS)

    Duan, Xiao-fei; Su, Xiu-juan; Guan, Lei; Zhang, Wei-she

    2017-07-01

    This article aims to discuss the methods of innovative by future scenarios design, to help the designers be more effective of the design of persimmon processing machinery. By analyzing the persimmon traditional processing process, conceiving persimmon processing future scenarios and using the UXD and Morphological matrix, it can get the comprehensive function schemes. It Select the most optimal schemes which match the future scenarios best by illustrating the schematic design of the rotary-light Dried-persimmon Processing Machinery. It is feasible and effective to carry out the scenario design research and construct the reasonable future scenario, and combine the function analysis method to carry on the product plan innovation and the development.

  6. European scenarios for exposure of soil organisms to pesticides.

    PubMed

    Tiktak, Aaldrik; Boesten, Jos J T I; Egsmose, Mark; Gardi, Ciro; Klein, Michael; Vanderborght, Jan

    2013-01-01

    Standardised exposure scenarios play an important role in European pesticide authorisation procedures (a scenario is a combination of climate, weather and crop data to be used in exposure models). The European Food Safety Authority developed such scenarios for the assessment of exposure of soil organisms to pesticides. Scenarios were needed for both the concentration in total soil and for the concentration in the liquid phase. The goal of the exposure assessment is the 90th percentile of the exposure concentration in the area of agricultural use of a pesticide in each of three regulatory European zones (North, Centre and South). A statistical approach was adopted to find scenarios that are consistent with this exposure goal. Scenario development began with the simulation of the concentration distribution in the entire area of use by means of a simple analytical model. In the subsequent two steps, procedures were applied to account for parameter uncertainty and scenario uncertainty (i.e. the likelihood that a scenario that is derived for one pesticide is not conservative enough for another pesticide). In the