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Sample records for a4-a parkersburg wv

  1. 75 FR 26793 - Fypon, Ltd., Parkersburg, WV, Including Workers Whose Unemployment Insurance, (UI) Wages Are Paid...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-12

    ...., Parkersburg, WV, Including Workers Whose Unemployment Insurance, (UI) Wages Are Paid through Therma-Tru Doors... Unemployment Insurance, (UI) Wages Are Paid Through Therma-Tru Doors, Archbold, OH; Amended Certification... employment at the subject firm had their wages reported under a separate unemployment insurance (UI) tax...

  2. 2. VIEW EAST, REAR. see also WV2371, WV2372, WV2373, WV23710, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. VIEW EAST, REAR. see also WV-237-1, WV-237-2, WV-237-3, WV-237-10, WV-237-F-2, WV-237-G-3 and historic photographs WV-237-11, WV-237-12, WV-237-13, WV-237-14, WV-237-18, WV-237-F-5) - Parsons Nursery, Original Wash House, South side of U.S. Route 219, Parsons, Tucker County, WV

  3. 2. VIEW SOUTH. (see also WV2371, WV2373, WV23710 and historic ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. VIEW SOUTH. (see also WV-237-1, WV-237-3, WV-237-10 and historic photographs WV-237-11, WV-237-12, WV-237-13, WV-237-14, WV-237-18, WV-237-22) - Parsons Nursery, Workshop-Warehouse, South side of U.S. Route 219, Parsons, Tucker County, WV

  4. Greening America's Capitals - Charleston, WV

    EPA Pesticide Factsheets

    This Greening America’s Capitals report outlines design concepts that could improve Slack Plaza in Charleston, WV, by creating more opportunities for local businesses, better managing stormwater runoff, and increasing green space.

  5. 78 FR 60376 - Proposed Collection: Direct Deposit Sign-Up Form

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-01

    ..., as required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A... Fiscal Service, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.... Sharp, Bureau of the Fiscal Service, 200 Third Street A4-A, Parkersburg, WV 26106-1328, (304) 480- 8150...

  6. WV Walks: replication with expanded reach.

    PubMed

    Reger-Nash, Bill; Bauman, Adrian; Cooper, Linda; Chey, Tien; Simon, Kenneth J; Brann, Maria; Leyden, Kevin M

    2008-01-01

    WV Walks replicated the Wheeling Walks community-wide campaign methodology to promote physical activity. A social marketing intervention promoted walking among insufficiently active 40- to 65-year-olds throughout the television media market in north-central West Virginia. The intervention included participatory planning, an 8-week mass media-based campaign, and policy and environmental activities. Pre and post random-digit-dial cohort telephone surveys were conducted at baseline and immediately postcampaign in intervention and comparison regions. The campaign resulted in maximal message awareness in north-central WV and demonstrated a significant increase in walking behavior represented by an absolute shift of 12% of the target population from insufficiently active to active (> or = 30 minutes, 5 days per week), versus the comparison community (adjusted odds ratio 1.82, CI: 1.05-3.17). Policy and environmental changes were also evident. This replication study increases our confidence that the initial effects observed in the Wheeling Walks intervention are generalizable to other similar rural communities.

  7. 77 FR 38394 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-27

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the... of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp.... Sharp, Bureau of the Public Debt, 200 Third Street A4-A, Parkersburg, WV 26106-1328, (304) 480-8150...

  8. RadNet Air Data From Charleston, WV

    EPA Pesticide Factsheets

    This page presents radiation air monitoring and air filter analysis data for Charleston, WV from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

  9. 75 FR 42 - Establishment of Class E Airspace; Spencer, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-04

    ... Aviation Administration (FAA), DOT. ACTION: Direct final rule; confirmation of effective date. SUMMARY: This action confirms the effective date of a direct final rule published in the Federal Register that establishes Class E Airspace at Spencer, WV. This action enhances the safety and airspace management of Boggs...

  10. 78 FR 48537 - West Virginia Disaster # WV-00033

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-08

    ... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 13681 and 13682] West Virginia Disaster WV-00033 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a Notice of the... INFORMATION CONTACT: A. Escobar, Office of Disaster Assistance, U.S. Small Business Administration, 409 3rd...

  11. 77 FR 55890 - West Virginia Disaster Number WV-00028

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-11

    ... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 13154 and 13155] West Virginia Disaster Number WV-00028 AGENCY: U.S. Small Business Administration. ACTION: Amendment 2. SUMMARY: This is an...: Submit completed loan applications to: U.S. Small Business Administration, Processing And Disbursement...

  12. 77 FR 45410 - West Virginia Disaster #WV-00028

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-31

    ... SMALL BUSINESS ADMINISTRATION [Disaster Declaration 13154 and 13155] West Virginia Disaster WV-00028 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a Notice of the... loan applications to: U.S. Small Business Administration, Processing And Disbursement Center, 14925...

  13. 76 FR 80230 - Amendment of Class E Airspace; Huntington, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-23

    ... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration 14 CFR Part 71 [Docket No. FAA-2011-1057; Airspace Docket No. 11-AEA-21] Amendment of Class E Airspace; Huntington, WV AGENCY: Federal...) Docket No. FAA-2011-1057. Interested parties were invited to participate in this rulemaking effort by...

  14. 1. Photocopied January 1973 from the Keystone Bridge Company Album, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Photocopied January 1973 from the Keystone Bridge Company Album, 1874. THE KEYSTONE BRIDGE COMPANY: LUCY FURNACE. - Baltimore & Ohio Railroad, Parkersburg Bridge, Ohio River, Parkersburg, Wood County, WV

  15. 76 FR 75464 - Approval and Promulgation of Air Quality Implementation Plans; West Virginia and Ohio...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-02

    ... 1997 Annual Fine Particle Standard for the Parkersburg-Marietta and Wheeling Nonattainment Areas AGENCY... Parkersburg-Marietta, West Virginia-Ohio (WV-OH) fine particle (PM 2.5 ) nonattainment area and the Wheeling... determined that the Parkersburg-Marietta, WV- OH and Wheeling, WV-OH fine particle (PM 2.5 ) nonattainment...

  16. White spotting variant (Wv) mouse as an experimental model for ovarian aging and menopausal biology

    PubMed Central

    Smith, Elizabeth R.; Yeasky, Toni; Wei, Jain Qin; Miki, Roberto A.; Cai, Kathy Q.; Smedberg, Jennifer L.; Yang, Wan-Lin; Xu, Xiang-Xi

    2011-01-01

    Objective Menopause is a unique phenomenon in modern women, as most mammalian species possess a reproductive period comparable to their lifespan. Menopause is caused by the depletion of germ cell-containing ovarian follicles, and in laboratory studies is usually modeled in animals in which the ovarian function is removed by ovariectomy or chemical poisoning of the germ cells. Our objective was to explore and characterize the white spotting variant (Wv) mice that have reduced ovarian germ cell abundance, a result of a point mutation in the c-kit gene that decreases the kinase activity, as a genetic model for use in menopausal studies. Methods Physiological and morphological features associated with menopause were determined in female Wv/Wv mice compared to age-matched wildtype controls. Immunohistochemistry was used to evaluate the presence and number of follicles in paraffin-embedded ovaries. Bone density and body composition were evaluated using the PIXImus X-ray densitometer, and lipids, calcium, and hormone levels were determined in serum using antigen-specific EIAs. Heart and body weight were measured, and cardiac function was evaluated by transthoracic echocardiography. Results The ovaries of the Wv/Wv females have a greatly reduced number of normal germ cells at birth compared to wildtype mice. The remaining follicles are depleted by around 2 months, and the ovaries develop benign epithelial lesions that resemble morphological changes that occur during ovarian aging, whereas a normal mouse ovary has numerous follicles at all stages of development and retains some follicles even in advanced age. Wv mice have elevated plasma gonadotrophins and reduced estrogen and progesterone levels, a significant reduction in bone mass density, and elevated serum cholesterol and lipoprotein levels. Moreover, the Wv female mice have enlarged hearts and reduced cardiac function. Conclusions The reduction of c-kit activity in Wv mice leads to a substantially diminished

  17. Efficacy of a topical application of Certifect® (fipronil 6.26% w/v, amitraz 7.48% w/v, (S)-methoprene 5.63% w/v) for the treatment of canine generalized demodicosis.

    PubMed

    Fourie, Josephus; Dumont, Pascal; Halos, Lénaïg; Beugnet, Frederic; Pollmeier, Matthias

    2013-01-01

    The efficacy of the treatment with Certifect ® (containing fipronil 6.26% w/v, amitraz 7.48% w/v, (S)-methoprene 5.63% w/v) applied topically was assessed in 18 dogs diagnosed with clinical generalized demodicosis. Three treatment regimens were compared over a 3-month period. Starting at Day 0, dogs were treated monthly (group 1) or every two weeks (group 2) with the combination of fipronil, amitraz, and (S)-methoprene or with monthly topical applications of the combination of amitraz and metaflumizone (group 3, reference treatment). Clinical examinations including deep skin scrapings were performed every month in order to evaluate the resolution of clinical signs and the reduction in mite counts. On Day 84, the percentage reduction of mite counts in group 1 was 99.8%, whereas no Demodex canis could be detected in groups 2 and 3 (i.e. 100% parasitological efficacy). As a result of the Demodex mite count reduction, the skin condition of the dogs improved significantly in all groups. This study illustrates, that both monthly and bi-weekly treatments with Certifect were effective in treating dogs with generalized demodicosis over a 3-month period. © J. Fourie et al., published by EDP Sciences, 2013.

  18. Efficacy of a topical application of Certifect® (fipronil 6.26% w/v, amitraz 7.48% w/v, (S)-methoprene 5.63% w/v) for the treatment of canine generalized demodicosis

    PubMed Central

    Fourie, Josephus; Dumont, Pascal; Halos, Lénaïg; Beugnet, Frederic; Pollmeier, Matthias

    2013-01-01

    The efficacy of the treatment with Certifect ® (containing fipronil 6.26% w/v, amitraz 7.48% w/v, (S)-methoprene 5.63% w/v) applied topically was assessed in 18 dogs diagnosed with clinical generalized demodicosis. Three treatment regimens were compared over a 3-month period. Starting at Day 0, dogs were treated monthly (group 1) or every two weeks (group 2) with the combination of fipronil, amitraz, and (S)-methoprene or with monthly topical applications of the combination of amitraz and metaflumizone (group 3, reference treatment). Clinical examinations including deep skin scrapings were performed every month in order to evaluate the resolution of clinical signs and the reduction in mite counts. On Day 84, the percentage reduction of mite counts in group 1 was 99.8%, whereas no Demodex canis could be detected in groups 2 and 3 (i.e. 100% parasitological efficacy). As a result of the Demodex mite count reduction, the skin condition of the dogs improved significantly in all groups. This study illustrates, that both monthly and bi-weekly treatments with Certifect were effective in treating dogs with generalized demodicosis over a 3-month period. PMID:24256940

  19. 77 FR 5090 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-01

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A)). Currently the... all written comments to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to make comments online is also...

  20. 77 FR 19057 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-29

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the... of consideration. ADDRESSES: Direct all written comments to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to...

  1. 77 FR 32178 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-31

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the... comments to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to make comments online is also available at www...

  2. 77 FR 43430 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-24

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the... comments to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to make comments online is also available at www...

  3. 78 FR 25535 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-01

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the... written comments to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to make comments online is also available at...

  4. 78 FR 59425 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-26

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the... Service, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov... INFORMATION CONTACT: Requests for additional information or copies should be directed to Bruce A. Sharp...

  5. 78 FR 63309 - Proposed Collection: Information Collected Through Investigative Inquiry Forms

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-23

    ... U.S.C. 3506(c)(2)(A). Currently the Bureau of the Fiscal Service within the Department of the...: Direct all written comments to Bureau of the Fiscal Service, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to make comments online is also...

  6. 78 FR 149 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-02

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the... consideration. ADDRESSES: Direct all written comments to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to make comments...

  7. 76 FR 61479 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-04

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the... written comments to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to make comments online is also available at...

  8. 77 FR 13175 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-05

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the... Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to make comments online is also available at www.pracomment.gov...

  9. 77 FR 13176 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-05

    ... 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the Bureau of the Public Debt within the Department of the.... Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity...: Requests for additional information or copies should be directed to Bruce A. Sharp, Bureau of the Public...

  10. 78 FR 22040 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-12

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A)). Currently the... Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to make comments online is also available at www.pracomment.gov...

  11. 77 FR 31689 - Proposed Information Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-29

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the.... Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity...: Requests for additional information or copies should be directed to Bruce A. Sharp, Bureau of the Public...

  12. 77 FR 74053 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-12

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the... consideration. ADDRESSES: Direct all written comments to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to make comments...

  13. 77 FR 32179 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-31

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A)). Currently the.... Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity...: Requests for additional information or copies should be directed to Bruce A. Sharp, Bureau of the Public...

  14. 78 FR 25534 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-01

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the... to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to make comments online is also available at www.pracomment...

  15. 78 FR 21706 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-11

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the... Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas... INFORMATION CONTACT: Requests for additional information or copies should be directed to Bruce A. Sharp...

  16. 77 FR 60026 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-01

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the... Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas... INFORMATION CONTACT: Requests for additional information or copies should be directed to Bruce A. Sharp...

  17. 77 FR 65248 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-25

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the... consideration. ADDRESSES: Direct all written comments to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to make comments...

  18. 77 FR 19057 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-29

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the... comments to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to make comments online is also available at www...

  19. 77 FR 32181 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-31

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A)). Currently the... of consideration. ADDRESSES: Direct all written comments to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to...

  20. 77 FR 43430 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-24

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the... consideration. ADDRESSES: Direct all written comments to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to make comments...

  1. 77 FR 13175 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-05

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the... written comments to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to make comments online is also available at...

  2. 77 FR 32179 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-31

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the.... ADDRESSES: Direct all written comments to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to make comments online is also...

  3. 77 FR 19058 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-29

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the...: Direct all written comments to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to make comments online is also...

  4. 77 FR 19424 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-30

    ..., as required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A..., Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The...: Requests for additional information or copies should be directed to Bruce A. Sharp, Bureau of the Public...

  5. 77 FR 69547 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-19

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the.... ADDRESSES: Direct all written comments to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to make comments online is also...

  6. 77 FR 32180 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-31

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the... the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd... INFORMATION CONTACT: Requests for additional information or copies should be directed to Bruce A. Sharp...

  7. 78 FR 71038 - Proposed Collection: Resolution for Transactions Involving Treasury Securities

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-27

    ... U.S.C. 3506(c)(2)(A). Currently the Bureau of the Fiscal Service within the Department of the.... ADDRESSES: Direct all written comments to Bureau of the Fiscal Service, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to make comments...

  8. ActiveWV: a systematic approach to developing a physical activity plan for West Virginia.

    PubMed

    Elliott, Eloise; Jones, Emily; Bulger, Sean

    2014-03-01

    Modeled after the National Physical Activity Plan (NPAP), ActiveWV 2015: The West Virginia Physical Activity Plan was developed to provide strategic direction for physical activity promotion within the state. The purpose of this manuscript is to describe the systematic approach taken in developing ActiveWV. Plan development began with establishing capacity and leadership among key stakeholders representing all societal sectors. A multiphase, statewide decision-making process allowed for input across sectors and geographic regions. The process results identified five priority areas that served as the conceptual framework for ActiveWV. Sector teams, comprised of key organization stakeholders across the eight sectors, finalized the sector-specific strategies and tactics using the NPAP evidence-based recommendations, results from a formalized strategic process, and the teams' expertise and experience. ActiveWV was officially released on January 19, 2012 at the State Capitol in Charleston, West Virginia. Community events throughout the state surrounded the release and celebrated West Virginia Physical Activity Day. Ongoing implementation and dissemination efforts are underway at state and local levels. As the NPAP calls for states and communities to develop plans that meet the needs of their particular context, other states may find the lessons learned from West Virginia helpful in the development process.

  9. 75 FR 65251 - Proposed Amendment of Class E Airspace; Charleston, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-22

    ...; Airspace Docket No. 10-AEA-24) and be submitted in triplicate to the Docket Management System (see... action proposes to modify Class E Airspace at Charleston, WV, to accommodate the additional airspace needed for the holding pattern associated with the new Standard Instrument Approach Procedures (SIAPs...

  10. 77 FR 33491 - American Woodmark Corporation, Moorefield, WV; Notice of Affirmative Determination Regarding...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-06

    ... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-81,287] American Woodmark Corporation, Moorefield, WV; Notice of Affirmative Determination Regarding Application for Reconsideration By... sufficient weight to justify reconsideration of the U.S. Department of Labor's prior decision. The...

  11. 76 FR 7584 - Matthews International Corporation, Bronze Division, Kingwood, WV; Notice of Affirmative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-10

    ... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-72,953] Matthews International Corporation, Bronze Division, Kingwood, WV; Notice of Affirmative Determination Regarding Application for.... Conclusion After careful review of the application, I conclude that the claim is of sufficient weight to...

  12. Exploring Climate Science with WV Educators: A Regional Model for Teacher Professional Development

    NASA Astrophysics Data System (ADS)

    Ruberg, L. F.; Calinger, M.

    2014-12-01

    The National Research Council Framework for K-12 Science Literacy reports that children reared in rural agricultural communities, who experience regular interactions with plants and animals, develop more sophisticated understanding of ecology and biological systems than do urban and suburban children of the same age. West Virginia (WV) is a rural state. The majority of its residents live in communities of fewer than 2,500 people. Based on the features of the population being served and their unique strengths, this presentation focuses on a regional model for teacher professional development that addresses agricultural and energy vulnerabilities and adaptations to climate change in WV. The professional development model outlined shows how to guide teachers to use a problem-based learning approach to introduce climate data and analysis techniques within a scenario context that is locally meaningful. This strategy engages student interest by focusing on regional and community concerns. Climate science standards are emphasized in the Next Generation Science Standards, but WV has not provided its teachers with appropriate instructional resources to meet those standards. The authors addressed this need by offering a series of climate science education workshops followed by online webinars offered to WV science educators free of charge with funding by the West Virginia Space Grant Consortium. The authors report on findings from this series of professional development workshops conducted in partnership with the West Virginia Science Teachers Association. The goal was to enhance grades 5-12 teaching and learning about climate change through problem-based learning. Prior to offering the climate workshops, all WV science educators were asked to complete a short questionnaire. As Figure 1 shows, over 40% of the teacher respondents reported being confident in teaching climate science content. For comparison post workshops surveys measure teacher confidence in climate science

  13. Higher Susceptibility of Mast-Cell-Deficient W/WV Mutant Mice to Brain Thromboembolism and Mortality Caused by Intravenous Injection of India Ink

    PubMed Central

    Kitamura, Y.; Taguchi, T.; Yokoyama, M.; Inoue, M.; Yamatodani, A.; Asano, H.; Koyama, T.; Kanamaru, A.; Hatanaka, K.; Wershil, B. K.; Galli, S. J.

    1986-01-01

    (WB × C57BL/6)F1-W/Wv mice possess a genetic defect in multipotential hematopoietic stem cells; the mice are anemic and lack mast cells. The authors injected diluted India ink intravenously into W/WV mice and congenic normal +/+ mice and searched for genetically determined differences in the development of complications of the injection. In both W/WV and +/+ mice, intravenous ink resulted in thrombocytopenia and markedly prolonged bleeding times, as well as prolonged partial thromboplastin and prothrombin times and reduced fibrinogen concentrations. These effects were similar in W/WV and +/+ mice, although the reduction in platelet counts was greater in W/WV mice. In addition, the mortality associated with ink injection was significantly higher in W/WV mice than in congenic +/+ mice. Most W/WV mice which died first exhibited paralysis, and examination under the dissection microscope revealed that ink injection resulted in significantly more cerebral thromboemboli in W/WV mice than in +/+ controls. Bone marrow transplantation from +/+ mice corrected both the mast cell deficiency and the anemia of W/WV mice and protected the W/WV recipients from the adverse consequences of ink injection. By contrast, +/+ mice rendered as anemic as W/WV mice by breeding did not exhibit increased morbidity and mortality after ink injection. (WC × C57BL/6)F1-S1/S1d mice, which are anemic and lack mast cells because of a genetic defect different from that of W/WV mice, also exhibited increased morbidity and mortality after intravenous ink. Finally, mixture of ink with commercial heparin prior to intravenous injection markedly reduced the incidence of cerebral thromboembolism and death in W/WV mice. Taken together, these findings suggest that the increased morbidity and mortality exhibited by W/WV and S1/S1d mice that received injected ink might be related to their mast cell deficiency rather than to their anemia. But measurement of the histamine content of the blood and various tissues

  14. 78 FR 72880 - Adequacy Status of the West Virginia Portion of the Steubenville-Weirton, WV-OH Nonattainment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-04

    ...In this notice, EPA is notifying the public that we have made insignificance findings through the transportation conformity adequacy process, under the Clean Air Act (CAA), for directly emitted fine particulate matter (PM2.5) and nitrogen oxides (NOX) in the West Virginia portion of the Steubenville- Weirton, WV-OH 1997 PM2.5 national ambient air quality standard (NAAQS) nonattainment area. West Virginia submitted the insignificance findings with the redesignation request and maintenance plan submittal on April 13, 2012. As a result of EPA's findings, the West Virginia portion of the Steubenville-Weirton, WV-OH nonattainment area is no longer required to perform a regional emissions analysis for directly emitted PM2.5, or NOx, as part of future PM2.5 conformity determinations for the 1997 annual PM2.5 air quality standard.

  15. 78 FR 72881 - Adequacy Status of the West Virginia Portion of the Steubenville-Weirton, WV-OH Nonattainment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-04

    ...In this notice, EPA is notifying the public that we have made insignificance findings through the transportation conformity adequacy process, under the Clean Air Act (CAA), for directly emitted fine particulate matter (PM2.5) and nitrogen oxides (NOX) in the West Virginia portion of the Steubenville- Weirton, WV-OH 2006 PM2.5 national ambient air quality standard (NAAQS) nonattainment area. West Virginia submitted the insignificance findings with the redesignation request and maintenance plan submittal on June 8, 2012. As a result of EPA's findings, the West Virginia portion of the Steubenville-Weirton, WV-OH nonattainment area is no longer required to perform a regional emissions analysis for directly emitted PM2.5, or NOX, as part of future PM2.5 conformity determinations for the 2006 daily PM2.5 air quality standard.

  16. W-V flap: a new technique for reconstruction of female distal urethral stricture using vestibular mucosa

    PubMed Central

    Dalela, Diwakar; Gupta, Piyush; Dalela, Disha; Govil, Tuhina

    2016-01-01

    A premenopausal woman having a totally occlusive distal urethral stricture, with suprapubic catheter (SPC) in situ, was referred to us for a definitive procedure. On discussion of the treatment options, the patient refused for a buccal or vaginal flap procedure. Thus, a local W-V flap was fashioned from the periurethral vestibular mucosa with seemingly excellent results, both in terms of resolution of her symptoms and a forwardly directed stream of urine without incontinence. PMID:27170612

  17. Inflammation induced by mast cell deficiency rather than the loss of interstitial cells of Cajal causes smooth muscle dysfunction in W/Wv mice

    PubMed Central

    Winston, John H.; Chen, Jinghong; Shi, Xuan-Zheng; Sarna, Sushil K.

    2014-01-01

    The initial hypothesis suggested that the interstitial cells of Cajal (ICC) played an essential role in mediating enteric neuronal input to smooth muscle cells. Much information for this hypothesis came from studies in W/Wv mice lacking ICC. However, mast cells, which play critical roles in regulating inflammation in their microenvironment, are also absent in W/Wv mice. We tested the hypothesis that the depletion of mast cells in W/Wv mice generates inflammation in fundus muscularis externa (ME) that impairs smooth muscle reactivity to Ach, independent of the depletion of ICC. We performed experiments on the fundus ME from wild type (WT) and W/Wv mice before and after reconstitution of mast cells by bone marrow transplant. We found that mast cell deficiency in W/Wv mice significantly increased COX-2 and iNOS expression and decreased smooth muscle reactivity to Ach. Mast cell reconstitution or concurrent blockade of COX-2 and iNOS restored smooth muscle contractility without affecting the suppression of c-kit in W/Wv mice. The expression of nNOS and ChAT were suppressed in W/Wv mice; mast cell reconstitution did not restore them. We conclude that innate inflammation induced by mast cell deficiency in W/Wv mice impairs smooth muscle contractility independent of ICC deficiency. The impairment of smooth muscle contractility and the suppression of the enzymes regulating the synthesis of Ach and NO in W/Wv mice need to be considered in evaluating the role of ICC in regulating smooth muscle and enteric neuronal function in W/Wv mice. PMID:24550836

  18. 14. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. MOUNT FARM OIL COMPANY. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  19. Existence of c-Kit negative cells with ultrastructural features of interstitial cells of Cajal in the subserosal layer of the W/Wv mutant mouse colon

    PubMed Central

    Tamada, Hiromi; Kiyama, Hiroshi

    2015-01-01

    Interstitial cells of Cajal (ICC) are mesenchymal cells that are distributed along the gastrointestinal tract and function as pacemaker cells or intermediary cells between nerves and smooth muscle cells. ICC express a receptor tyrosine kinase c-Kit, which is an established marker for ICC. The c-kit gene is allelic with the murine white-spotting locus (W), and some ICC subsets were reported to be missing in heterozygous mutant W/Wv mice carrying W and Wv mutated alleles. In this study, the characterization of interstitial cells in the subserosal layer of W/Wv mice was analyzed by immunohistochemistry and electron microscopy. In the proximal and distal colon of W/Wv mutant mice, no c-Kit-positive cells were detected in the subserosal layer by immunohistochemistry. By electron microscopy, the interstitial cells, which were characterized by the existence of caveolae, abundant mitochondria and gap junctions, were observed in the W/Wv mutant colon. The morphological characteristics were comparable to those of the multipolar c-Kit positive ICC seen in the subserosa of proximal and distal colon of wild-type mice. Fibroblasts were also located in the same layers, but the morphology of the fibroblasts was distinguishable from that of ICC in wild type mice or of ICC-like cells in W/Wv mutant mice. Collectively, it is concluded that c-Kit-negative interstitial cells showing a typical ICC ultrastructure exist in the proximal and distal colon of W/Wv mutant mice. PMID:26727725

  20. Existence of c-Kit negative cells with ultrastructural features of interstitial cells of Cajal in the subserosal layer of the W/Wv mutant mouse colon.

    PubMed

    Tamada, Hiromi; Kiyama, Hiroshi

    2015-01-01

    Interstitial cells of Cajal (ICC) are mesenchymal cells that are distributed along the gastrointestinal tract and function as pacemaker cells or intermediary cells between nerves and smooth muscle cells. ICC express a receptor tyrosine kinase c-Kit, which is an established marker for ICC. The c-kit gene is allelic with the murine white-spotting locus (W), and some ICC subsets were reported to be missing in heterozygous mutant W/Wv mice carrying W and Wv mutated alleles. In this study, the characterization of interstitial cells in the subserosal layer of W/Wv mice was analyzed by immunohistochemistry and electron microscopy. In the proximal and distal colon of W/Wv mutant mice, no c-Kit-positive cells were detected in the subserosal layer by immunohistochemistry. By electron microscopy, the interstitial cells, which were characterized by the existence of caveolae, abundant mitochondria and gap junctions, were observed in the W/Wv mutant colon.The morphological characteristics were comparable to those of the multipolar c-Kit positive ICC seen in the subserosa of proximal and distal colon of wild-type mice. Fibroblasts were also located in the same layers,but the morphology of the fibroblasts was distinguishable from that of ICC in wild type mice or of ICC-like cells in W/Wv mutant mice. Collectively, it is concluded that c-Kit-negative interstitial cells showing a typical ICC ultrastructure exist in the proximal and distal colon of W/Wv mutant mice.

  1. Effect of heat treatment on the microstructure of a 2CrMoNiWV rotor steel

    NASA Astrophysics Data System (ADS)

    Li, Cheng

    A wide range of experiments have been carried out on a 2CrMoNiWV low alloy steel to investigate the effect of various heat treatment conditions on microstructural change, alloy carbide transformation mechanism and mechanical properties.Two complete continuous cooling transformation (CCT) diagrams were constructed for this steel on the basis of experimental dilatometry thermal analysis, metallographic examination and current phase transformation theory. The significance of these two diagrams is in that they can be directly utilised in industrial practice as a reference during heat treatment for this material. Meanwhile it was confirmed that this 2CrMoNiWV steel can be transformed to a fully bainitic microstructure over a wide range of cooling rates and this feature proved this steel suitable for large diameter steam turbine rotor application.An innovative carbide extraction technique for the XRD identification of carbide phase has been developed. The detailed description of this new technique and its advantages are discussed in this thesis. The extensive work using TEM/EDX has set up essential "finger prints" for the quick examination of large amounts of individual carbide existing at various heat treated conditions. Simultaneous measurements and determinations were made on particle composition, morphological change, the type, amount and distribution of these carbide phases. Thus the sequence of carbide transformation for this 2CrMoNiWV steel during tempering has been established.The characteristic microstructures of various heat treated specimens were carefully examined and discussed. Theoretical thermodynamic equilibria predictions were calculated using MTDATA. A very good agreement was found between experimental results and theoretical predictions on those critical transformation temperatures and a good correlation of carbide evolution sequences was obtained. Based on experimental results and theoretical predictions, the role of tungsten in promoting creep

  2. Improvement of anemia in W/WV mice by recombinant human erythropoietin (rHuEPO) mediated through EPO receptors with lowered affinity.

    PubMed

    Kabaya, K; Akiyama, H; Nishi, N; Misaizu, T; Okada, Y; Kawagishi, M; Amano, K; Kusaka, M; Seki, M; Uzumaki, H

    1995-01-01

    We studied the effects of recombinant human erythropoietin (rHuEPO) on anemic W/WV mice which manifested severe anemia accompanied by mutation of the W gene encoding tyrosine kinase type receptor (c-kit gene) of bone marrow hematopoietic cells. Nine-week-old male W/WV mice or normal littermates (+/+) were used. Since serum EPO concentration in W/WV mice increased in proportion to severity of anemia, EPO production in the kidneys of these animals was found to be regulated normally. Hematocrit in +/+ mice increased and a maximal response was also obtained with 2,000 IU/kg of rHuEPO. On the other hand, hematocrit in W/WV mice increased in a dose-responsive manner by administration with 2,000 and 10,000 IU/kg, showing different responses to rHuEPO in these two types of mice. The responsiveness of W/WV mice to rHuEPO was low in terms of increases in erythroblastic precursor cells (CFU-E), and immature cells in the bone marrow. Scatchard analysis of the specific binding of 125I-rHuEPO against bone marrow cells revealed that the different responsiveness to rHuEPO between W/WV and +/+ mice may be correlated with differences in affinity of EPO receptor of bone marrow cells in these mice. From these results, a high dose of rHuEPO is capable of improving the anemia in W/WV mice that had EPO receptors with lowered affinity, indicating the possible effectiveness of rHuEPO in anemic patients with EPO receptor abnormality.

  3. Efficacy of Droncit Spot-on (praziquantel) 4% w/v against immature and mature Echinococcus multilocularis in cats.

    PubMed

    Jenkins, D J; Romig, T

    2000-07-01

    The causative agent of alveolar hydatidosis in humans, the fox tapeworm Echinococcus multilocularis, is extending its geographical range in Europe and has been found in domestic cats in some areas. A dermally applied cestocidal treatment for domestic cats has been developed and the efficacy of this treatment is reported. Thirty purpose-bred cats were experimentally infected each with 10000 protoscoleces of Echinococcus multilocularis. Ten days later one group of ten cats was treated with Droncit(R) Spot-on (Praziquantel) 4% w/v dermally in one place on the dorsal aspect of the neck at a dose of 8 mg/kg. Eleven days later (21 days p.i.) a second group of ten cats was also treated with Droncit(R) Spot-on the same way. One group of ten cats was left untreated as controls. Twenty three days after infection the cats were examined for the presence of E. multilocularis tapeworms. No E. multilocularis were recovered from any of the cats in either of the treated groups. Echinococcus multilocularis were recovered from eight of the ten cats left untreated as controls. The worm burdens in the untreated cats were 0, 0, 5, 15, 75, 110, 220, 815, 2635, and 3045 worms per cat. The worms ranged in development from the three to four segment stage. Many of the E. multilocularis with four segments contained unshelled eggs in the terminal segment. This study indicates that Droncit(R) Spot-on (Praziquantel) 4% w/v applied dermally at 8 mg/kg is highly effective in removing E. multilocularis from the small intestine of cats infected with immature and mature (prepatent) infections of E. multilocularis. In the cats with the mature infections all tapeworms were absent from the small intestine within 2 days of treatment.

  4. Expression of alpha and beta subunit isoforms of Na,K-ATPase in the mouse inner ear and changes with mutations at the Wv or Sld loci.

    PubMed

    Schulte, B A; Steel, K P

    1994-07-01

    Mice homozygous for mutations at the viable dominant spotting (Wv) and Steel-dickie (Sld) loci exhibit a similar phenotype which includes deafness. The auditory dysfunction derives from failure of the stria vascularis to develop normally and to generate a high positive endocochlear potential (EP). Because strial function is driven by Na,K-ATPase its expression was investigated in inner ears of Wv/Wv and Sld/Sld mice and their wild-type littermates by immunostaining with antisera against four of the enzyme's subunit isoforms. Wild-type mice from two different genetic backgrounds showed an identical distribution of subunit isoforms among inner ear transport cells. Several epithelial cell types coexpressed the alpha 1 and beta 1 subunits. Vestibular dark cells showed no reactivity for beta 1 but expressed abundant beta 2, whereas, strial marginal cells stained strongly for both beta isoforms. The only qualitative difference between mutant and wild-type mice was the absence of beta 1 subunit in marginal cells of the mutant's stria. However, it is unlikely that this difference accounts for failure of mutants to generate a high EP because the beta 1 subunit is not present in the stria vascularis of either rats or gerbils with normal EP values. Strong immunostaining for Na,K-ATPase in lateral wall fibrocytes of normal mice along with diminished immunoreactivity in the mutants supports the concept that these strategically located transport fibrocytes actively resorb K+ leaked across Reissner's membrane into scala vestibuli or effluxed from hair cells and nerves into scala tympani. It is further speculated that the resorbed K+ normally is siphoned down its concentration gradient into the intrastrial space through gap junctions between fibrocytes and strial basal and intermediate cells where it is recycled back to endolymph via marginal cells. Thus, failure of mutants to generate a positive EP could be explained by the absence of intermediate cells which may form the final

  5. Goldstone radar images of near-Earth asteroids (469896) 2007 WV4, 2014 JO25, 2017 BQ6, and 2017 CS

    NASA Astrophysics Data System (ADS)

    Brozovic, Marina; Benner, Lance A. M.; Naidu, Shantanu P.; Giorgini, Jon D.; Busch, Michael; Jao, Joseph; Lee, Clement; Snedeker, Lawrence; Silva, Marc; Slade, Martin A.; Lawrence, Kenneth J.

    2017-10-01

    We report Goldstone delay-Doppler radar imaging of four NEAs obtained during February-June 2017. The signal-to-noise ratios were very strong for each object and we obtained detailed images with range resolutions as fine as 3.75 m/pixel. Delay-Doppler imaging revealed that 2017 BQ6 is a strikingly angular object roughly ~200 m in diameter with a rotation period of ~3 h. The multi-faceted shape is puzzling assuming a rubble-pile structure of this asteroid. 2017 CS was discovered by Pan-STARRS 1 on February 2 and approached within 8 lunar distances on May 29. 2017 CS appears rounded on large scales but has considerable fine-scale topography evident along its leading edges. The images suggest a diameter of ~1 km and rotation visible in the images is consistent with the 40 h rotation period obtained independently by from photometry by P. Pravec (pers. comm.). The highest resolution images show evidence for meter-size boulders, ridges, and broad concavities. 2007 WV4 was imaged in late May and early June. 2007 WV4 appears distinctly angular, with a diameter in the realm of 900 meters, and with at least three large facets more than 100 m in extent. Tracking of features in the images gives a rotation period of about 12 hours. The echoes show a persistent, small topographic feature that extends out from the surface. The nature of this feature is unknown, but it may be a large boulder similar to Yoshinodai seen on 25143 Itokawa. 2014 JO25 approached within 4.6 lunar distances on April 19. This was the closest encounter by an asteroid with an absolute magnitude brighter than 18 known in advance until 2027, when 1999 AN10 will approach within one lunar distance. Radar imaging shows that 2014 JO25 is an irregular object, which consists of two components connected by a narrow neck. The asteroid has a long axis of about 1 km and a short axis of roughly 600 m. The 3.75 m range resolution imaging placed thousands of pixels on the object and reveals ridges, hills, concavities, flat

  6. Fuchs Lubricants, Inc., Huntington, WV

    EPA Pesticide Factsheets

    EPA Region III will issue a proposed penalty of $85,000.00 against Fuchs Lubricants, Inc. The penalty is for violations of CWA regulations found at 40 C.F.R. Part 112, Oil Pollution Prevention regulations,

  7. Upscaling the impact of convective overshooting (COV) through BRAMS: a continental and wet-season scale study of the water vapour (WV) budget in the tropical tropopause layer (TTL).

    NASA Astrophysics Data System (ADS)

    Behera, Abhinna; Rivière, Emmanuel; Marécal, Virginie; Rysman, Jean-François; Claud, Chantal; Burgalat, Jérémie

    2017-04-01

    The stratospheric water vapour (WV) has a conceding impact on the radiative and chemical budget of Earth's atmosphere. The convective overshooting (COV) at the tropics is well admitted for playing a role in transporting directly WV to the stratosphere. Nonetheless, its impact on the lower stratosphere is yet to be determined at global scale, as the satellite and other air-borne measurements are not of having fine enough resolution to quantify this impact at large scale. Therefore, efforts have been made to quantify the influence of COV over the WV budget in the tropical tropopause layer (TTL) through modelling. Our approach is to build two synthetic tropical wet-seasons; where one would be having only deep convection (DC) but no COV at all, and the second one would be having the COV, and in both cases the WV budget in the TTL would be estimated. Before that, a French-Brazilian TRO-pico campaign was carried out at Bauru, Brazil in order to understand the influence of COV on the WV budget in the TTL. The radio-sounding, and the small balloon-borne WV measurements from the campaign are being utilized to validate the model simulation. Brazilian version of Regional Atmospheric Modeling System (BRAMS) is used with a single grid system to simulate a WV variability in a wet-season. Grell's convective parameterization with ensemble closure, microphysics with double moment scheme and 7 types of hydrometeors are incorporated to simulate the WV variability for a wet-season at the tropics. The grid size of simulation is chosen to be 20 km x 20 km horizontally and from surface to 30 km altitude, so that there cannot be COV at all, only DC due to such a relatively coarse resolution. The European Centre for Medium-range Weather Forecasts (ECMWF) operational analyses data are used every 6 hours for grid initialization and boundary conditions, and grid center nudging. The simulation is carried out for a full wet-season (Nov 2012 - Mar 2013) at Brazilian scale, so that it would

  8. Goldstone radar imaging of near-Earth asteroids (469896) 2007 WV4, 2014 JO25, 2017 BQ6, and 2017 CS

    NASA Astrophysics Data System (ADS)

    Naidu, S.; Benner, L.; Brozovic, M.; Giorgini, J. D.; Busch, M.; Jao, J. S.; Lee, C. G.; Snedeker, L. G.; Silva, M. A.; Slade, M. A.; Lawrence, K. J.

    2017-12-01

    We present Goldstone radar imaging of four near-Earth asteroids during Feb-Jun 2017. The signal-to-noise ratios were very strong for each object and we obtained detailed images with range resolutions as fine as 3.75 m/pixel. 2017 BQ6 was discovered on Jan 26 and approached Earth within 6.5 lunar distances on Feb 7. Radar images show that it is a strikingly angular object roughly 200 m in diameter with a rotation period of 3 h. Its multi-faceted shape challenges the expectation that it is a rubble pile. 2017 CS was discovered on Feb 2 and approached within 8 lunar distances on May 29. It appears rounded on large scales but has considerable fine-scale topography evident along its leading edges. The images suggest a diameter of 1 km and a spin period consistent with the 40 h period obtained from photometry by P. Pravec (pers. comm.). The highest resolution images show evidence for meter-size boulders, ridges, and broad concavities. 2007 WV4 was imaged in late May and early June, has a diameter of 900 meters, and appears distinctly angular with at least three large facets > 100 m in extent. Tracking of features in the images gives a rotation period of about 12 hours. 2014 JO25 approached within 4.6 lunar distances on April 19. This was the closest encounter by an asteroid with an absolute magnitude brighter than 18 known in advance until 2027, when 1999 AN10 will approach within one lunar distance. Radar imaging shows that 2014 JO25 is an irregular object, consisting of two components connected by a narrow neck. The asteroid has pole on dimensions of roughly 1 x 0.6 km in the images. Imaging with 3.75 m/pixel resolution places thousands of pixels on the object and reveals ridges, concavities, flat regions up to 200 meters long, and radar-bright spots suggestive of boulders. Tracking of features in the images yields a rotation period of about 4.5 hours that is among the fastest of the 50 known contact binaries in the near-Earth population.

  9. Long-term monoclonal reconstitution of erythropoiesis in genetically anemic W/Wv mice by injection of 5-fluorouracil-treated bone marrow cells of Pgk-1b/Pgk-1a mice

    SciTech Connect

    Nakano, T.; Waki, N.; Asai, H.

    The spleen colony-forming assay does not represent the number of hematopoietic stem cells with extensive self-maintaining capacity because five to 50 spleen colony-forming units (CFU-S) are necessary to rescue a genetically anemic (WB X C57BL/6)F1-W/Wv(WBB6F1-W/Wv) mouse. We investigated which is more important for the reconstitution of erythropoiesis, the transplantation of multiple CFU-S or that of a single stem cell with extensive self-maintaining potential. The electrophoretic pattern of hemoglobin was used as a marker of reconstitution and that of phosphoglycerate kinase (PGK), an X chromosome-linked enzyme, as a tool for estimating the number of stem cells. For this purpose, we developedmore » the C57BL/6 congeneic strain with the Pgk-1a gene. Bone marrow cells were harvested after injection of 5-fluorouracil from C57BL/6-Pgk-1b/Pgk-1a female mice in which each stem cell had either A-type PGK or B-type PGK due to the random inactivation of one or two X chromosomes. When a relatively small number of bone marrow cells (ie, 10(3) or 3 X 10(3) were injected into 200-rad-irradiated WBB6F1-W/Wv mice, the hemoglobin pattern changed from the recipient type (Hbbd/Hbbs) to the donor type (Hbbs/Hbbs) in seven of 150 mice for at least 8 weeks. Erythrocytes of all these WBB6F1-W/Wv mice showed either A-type PGK alone or B-type PGK alone during the time of reconstitution, which suggests that a single stem cell with extensive self-maintaining potential may sustain the whole erythropoiesis of a mouse for at least 8 weeks.« less

  10. Synthesis, Crystal Structures, Magnetic Properties, and Theoretical Investigation of a New Series of NiII-LnIII-WV Heterotrimetallics: Understanding the SMM Behavior of Mixed Polynuclear Complexes.

    PubMed

    Vieru, Veacheslav; Pasatoiu, Traian D; Ungur, Liviu; Suturina, Elizaveta; Madalan, Augustin M; Duhayon, Carine; Sutter, Jean-Pascal; Andruh, Marius; Chibotaru, Liviu F

    2016-12-05

    The polynuclear compounds containing anisotropic metal ions often exhibit efficient barriers for blocking of magnetization at fairly arbitrary geometries. However, at variance with mononuclear complexes, which usually become single-molecule magnets (SMM) under the sole requirement of a highly axial crystal field at the metal ion, the factors influencing the SMM behavior in polynuclear complexes, especially, with weakly axial magnetic ions, still remain largely unrevealed. As an attempt to clarify these conditions, we present here the synthesis, crystal structures, magnetic behavior, and ab initio calculations for a new series of Ni II -Ln III -W V trimetallics, [(CN) 7 W(CN)Ni(H 2 O)(valpn)Ln(H 2 O) 4 ]·H 2 O (Ln = Y 1, Eu 2, Gd 3, Tb 4, Dy 5, Lu 6). The surprising finding is the absence of the magnetic blockage even for compounds involving strongly anisotropic Dy III and Tb III metal ions. This is well explained by ab initio calculations showing relatively large transversal components of the g-tensor in the ground exchange Kramers doublets of 1 and 4 and large intrinsic tunneling gaps in the ground exchange doublets of 3 and 5. In order to get more insight into this behavior, another series of earlier reported compounds with the same trinuclear [W V Ni II Ln III ] core structure, [(CN) 7 W(CN)Ni(dmf)(valdmpn)Ln(dmf) 4 ]·H 2 O (Ln = Gd III 7, Tb III 8a, Dy III 9, Ho III 10), [(CN) 7 W(CN)Ni(H 2 O)(valdmpn)Tb(dmf) 2.5 (H 2 O) 1.5 ]·H 2 O·0.5dmf 8b, and [(CN) 7 W(CN)Ni(H 2 O)(valdmpn)Er(dmf) 3 (H 2 O) 1 ]·H 2 O·0.5dmf 11, has been also investigated theoretically. In this series, only 8b exhibits SMM behavior which is confirmed by the present ab initio calculations. An important feature for the entire series is the strong ferromagnetic coupling between Ni(II) and W(V), which is due to an almost perfect trigonal dodecahedron geometry of the octacyano wolframate fragment. The reason why only 8b is an SMM is explained by positive zero-field splitting on the nickel

  11. Production of large numbers of hybridomas producing monoclonal antibodies against rat IgE using mast cell-deficient w/wv and sl/sld strains of mice.

    PubMed

    Rup, B J

    1989-08-15

    A number of different mouse strains and immunization protocols were used to attempt to make monoclonal antibodies against rat IgE for use in studies of the structure, biological activities and regulation of this class of antibody. Successful production of large numbers of monoclonal antibodies was achieved when mast cell deficient (w/wv and sl/sld) but not conventional (BALB/c, CAF1 or SJL) mice were used. These results suggest that the poor response of conventional strains of mice to rat IgE may be due to the presence of mast cells bearing high affinity receptors for IgE in these mice.

  12. 76 FR 55737 - Proposed Privacy Act Systems of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-08

    ... Associate Chief Human Capital Officer for Civil Rights and Diversity, Department of the Treasury, 1500... policies and practices: Associate Chief Human Capital Officer for Civil Rights and Diversity. The system.... (9) BPD: EEO Officer, 200 3rd Street, Room 102, Parkersburg, WV 26106. (10) FinCEN: Chief, Outreach...

  13. 76 FR 26801 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-09

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the... to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street, Avery 4-A, Parkersburg, WV 26106- 5312, or e-mail to Bruce.Sharp@bpd.treas.gov . FOR FURTHER INFORMATION CONTACT: Requests for additional...

  14. 76 FR 26802 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-09

    ... required by the Paperwork Reduction Act of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the... to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street, Avery 4-A, Parkersburg, WV 26106- 5312, or e-mail to Bruce.Sharp@bpd.treas.gov FOR FURTHER INFORMATION CONTACT: Requests for additional...

  15. 78 FR 341 - Proposed Information Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-03

    ..., Parkersburg, WV 26106-1328, (304) 480-8150. SUPPLEMENTARY INFORMATION: Form Numbers and Title: PD F 5354--FHA Transaction Request; PD F 5366--FHA New Account Request; PD F 5367--FHA Debenture Transfer Request. OMB Number: 1535-0102. Abstract: The information is used to (1) Establish a book-entry account; (2) change...

  16. 31 CFR 341.10 - Reissue.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... the case of a bond registered in beneficiary form upon the owner's request on Form PD 3564. No consent..., Parkersburg, WV 26101. [28 FR 405, Jan 16, 1963, as amended at 42 FR 21611, Apr. 28, 1977; 42 FR 57123, Nov. 1...

  17. 31 CFR 341.10 - Reissue.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... the case of a bond registered in beneficiary form upon the owner's request on Form PD 3564. No consent..., Parkersburg, WV 26101. [28 FR 405, Jan 16, 1963, as amended at 42 FR 21611, Apr. 28, 1977; 42 FR 57123, Nov. 1...

  18. 31 CFR 341.10 - Reissue.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the case of a bond registered in beneficiary form upon the owner's request on Form PD 3564. No consent..., Parkersburg, WV 26101. [28 FR 405, Jan 16, 1963, as amended at 42 FR 21611, Apr. 28, 1977; 42 FR 57123, Nov. 1...

  19. Linkage and association of haplotypes at the APOA1/C3/A4/A5 genecluster to familial combined hyperlipidemia

    SciTech Connect

    Eichenbaum-Voline, Sophie; Olivier, Michael; Jones, Emma L.

    2002-09-15

    Combined hyperlipidemia (CHL) is a common disorder of lipidmetabolism that leads to an increased risk of cardiovascular disease. Thelipid profile of CHL is characterised by high levels of atherogeniclipoproteins and low levels of high-density-lipoprotein-cholesterol.Apolipoprotein (APO) A5 is a newly discovered gene involved in lipidmetabolism located within 30kbp of the APOA1/C3/A4 gene cluster. Previousstudies have indicated that sequence variants in this cluster areassociated with increased plasma lipid levels. To establish whethervariation at the APOA5 gene contributes to the transmission of CHL, weperformed linkage and linkage disequilibrium (LD) tests on a large cohortof families (n=128) with familial CHL (FCHL). The linkage datamore » producedevidence for linkage of the APOA1/C3/A4/A5 genomic interval to FCHL (NPL= 1.7, P = 0.042). The LD studies substantiated these data. Twoindependent rare alleles, APOA5c.56G and APOC3c.386G of this gene clusterwere over-transmitted in FCHL (P = 0.004 and 0.007, respectively), andthis was associated with a reduced transmission of the most commonAPOA1/C3/A4/A5 haplotype (frequency 0.4425) to affected subjects (P =0.013). The APOA5c.56G allele was associated with increased plasmatriglyceride levels in FCHL probands, whereas the second, andindependent, APOC3c.386G allele was associated with increased plasmatriglyceride levels in FCHL pedigree founders. Thus, this allele (or anallele in LD) may mark a quantitative trait associated with FCHL, as wellas representing a disease susceptibility locus for the condition. Thisstudy establishes that sequence variation in the APOA1/C3/A4/A5 genecluster contributes to the transmission of FCHL in a substantialproportion of affected families, and that these sequence variants mayalso contribute to the lipid abnormalities of the metabolic syndrome,which is present in up to 40 percent of persons with cardiovasculardisease.« less

  20. Inhibition of cytochrome P450 enzymes by saturated and unsaturated fatty acids in human liver microsomes, characterization of enzyme kinetics in the presence of bovine serum albumin (0.1 and 1.0% w/v) and in vitro - in vivo extrapolation of hepatic clearance.

    PubMed

    Palacharla, Raghava Choudary; Uthukam, Venkatesham; Manoharan, Arunkumar; Ponnamaneni, Ranjith Kumar; Padala, Nagasurya Prakash; Boggavarapu, Rajesh Kumar; Bhyrapuneni, Gopinadh; Ajjala, Devender Reddy; Nirogi, Ramakrishna

    2017-04-01

    The objective of the study was to determine the effect of fatty acids on CYP enzymes and the effect of BSA on intrinsic clearance of probe substrates. The inhibitory effect of thirteen fatty acids including saturated, mono-unsaturated and polyunsaturated fatty acids on CYP enzymes, kinetic parameters and intrinsic clearance values of nine CYP marker probe substrate reactions in the absence and presence of BSA (0.1 and 1.0% w/v) were characterized in human liver microsomes. The results demonstrate that most of the unsaturated fatty acids showed marked inhibition towards CYP2C8 mediated amodiaquine N-deethylation followed by inhibition of CYP2C9 and CYP2B6 mediated activities. The addition of 0.1% BSA in the incubation markedly improved the unbound intrinsic clearance values of probe substrates by reducing the K m values with little or no effect on maximal velocity. The addition of BSA (0.1 and 1.0% w/v) did not influence the unbound intrinsic clearance of marker reactions for CYP2A6, and CYP3A4 enzymes. The addition of 0.1% w/v BSA is sufficient to determine the intrinsic clearance of marker probe reactions by metabolite formation approach. The predicted hepatic clearance values for the substrates using the well-stirred model, in the presence of BSA (0.1% BSA), are comparable to the in vivo hepatic clearance values. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. The APOA1/C3/A4/A5 cluster and markers of allostatic load in the Boston Puerto Rican Health Study

    USDA-ARS?s Scientific Manuscript database

    The APOA1/C3/A4/A5 cluster encodes key regulators of plasma lipids. Interactions between dietary factors and single nucleotide polymorphisms (SNPs) in the cluster have been reported. Allostatic load, or physiological dysregulation in response to stress, has been implicated in shaping health disparit...

  2. 76 FR 28312 - Safety Zones; Fireworks Display Kanawha River, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ... expect the economic impact of this rule to be so minimal that a full Regulatory Evaluation is unnecessary... significant economic impact on a substantial number of small entities. The term ``small entities'' comprises... Guard certifies under 5 U.S.C. 605(b) that this rule would not have a significant economic impact on a...

  3. 76 FR 34606 - Special Local Regulation; Monongahela River, Morgantown, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-14

    ... mile marker 101.0 (Morgantown Highway Bridge) to mile marker 102.0 (Morgantown Lock and Dam) on the... mile marker 101.0 (Morgantown Highway Bridge) to mile marker 102.0 (Morgantown Lock and Dam) on the... mile marker 101.0 (Morgantown Highway Bridge) to mile marker 102.0 (Morgantown Lock and Dam) on the...

  4. 75 FR 43 - Modification of Class E Airspace; Beckley, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-04

    ... and management of the aircraft operations at Raleigh County Memorial Airport. DATES: Effective 0901... Aviation Administration (FAA), DOT. ACTION: Direct final rule, confirmation of effective date. SUMMARY: This action confirms the effective date of a direct final rule published in the Federal Register that...

  5. 78 FR 55770 - West Virginia Disaster #WV-00032

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-11

    ... Administrative declaration of a disaster for the State of West Virginia dated 08/29/2013. Incident: Severe Storms and Heavy Rain. Incident Period: 06/12/2013 through 06/19/2013. Effective Date: 08/29/2013. Physical...

  6. Skidders, Trucking, and Fellers limiting Factors in WV Logging Industry

    Treesearch

    William G. Luppold; Curt C. Hassler; Shawn Grushecky; Shawn Grushecky

    1998-01-01

    Like many states in the Central Appalachian region West Virginia has experienced a continual expansion in primary hardwood processing capacity during the 1990s. In the early part of the decade, hardwood sawmill capacity increased by nearly 40 percent to more than 700 million board feet per year. In the mid and late 1990s, several other primary processing facilities...

  7. 75 FR 11582 - West Virginia Disaster # WV-00015

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-11

    .... Economic Injury (EIDL) Loan Application Deadline Date: 12/02/2010. ADDRESSES: Submit completed loan.../2010, Private Non- Profit organizations that provide essential services of governmental nature may file... Economic Injury: Non-Profit Organizations without Credit Available 3.000 Elsewhere The number assigned to...

  8. 76 FR 71936 - Upper Deckers Creek Watershed, Preston County, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-21

    .... Alternatives under consideration include the addition of rural raw water supply as a project purpose and increasing the reservoir volume, evaluating other raw water supply sources, raising the top of the dam...

  9. Nobody Asked Us: The WV Welfare Reform Listening Project.

    ERIC Educational Resources Information Center

    Wilson, Rick

    West Virginia's state welfare reform plan was in effect by the end of 1997. In 1999, over 175 interviews were conducted with past and present welfare recipients to bring their experiences and concerns to the attention of the public and policymakers. Nearly all interviewees were women and were taking part in work activities. In general, welfare…

  10. Endangered species identification along corridors in WV using GIS.

    DOT National Transportation Integrated Search

    2006-08-11

    Since the late 19th century, the exploitation of oil, gas, timber, and mineral resources in Appalachia has been associated with the production of an extensive transportation system and with a concurrent decline in the environmental quality of aquatic...

  11. 77 FR 3836 - Supplemental Environmental Impact Statement, Mingo County, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-25

    ... Mountain Surface Mine Clean Water Act Section 404 Permit Application. The FHWA and USACE are joint-lead... 2000 FEIS and approved in the 2000 ROD. The USACE is evaluating a Clean Water Act (CWA) Section 404... to surface water and groundwater resources, including aquatic habitat, water quantity and quality...

  12. Sputtering Deposition of Sandwich-Structured V2O5/Metal (V, W)/V2O5 Multilayers for the Preparation of High-Performance Thermally Sensitive VO2 Thin Films with Selectivity of VO2 (B) and VO2 (M) Polymorph.

    PubMed

    Liu, Hengwu; Wan, Dongyun; Ishaq, Ahmad; Chen, Lanli; Guo, Beibei; Shi, Siqi; Luo, Hongjie; Gao, Yanfeng

    2016-03-01

    For specific application to an uncooled infrared detector, VO2 thin films should have a series of characteristics including purposefully chosen polymorphs, accurate stoichiometry, phase stabilization, a high temperature-coefficient of resistance (TCR), and suitable square-resistance. This work reports controllable preparation of high-performance VO2 films via post annealing of a sandwich-structured V2O5/metal (V, W)/V2O5 multilayer precursor, which was deposited by RF magnetron sputtering. This sandwich structure can dynamically regulate oxygen contents and doping element levels in the films, enabling us to achieve accurate regulation of stoichiometry and polymorphs. The precursor films undergo a B to M phase transition depending on the quantity of the metal layers. At the thickness of the metal layer below a limitation, the resulting film after heat treatment was VO2 (B), and above the limitation, the product was VO2 (M). The optical modulation of the VO2 (M) in the near-infrared region can be tuned from 1.2 to 39.8% (ΔT2000 nm). TCR values can range from -1.89 to -4.29%/K and the square-resistances at room temperature (R0) from 69.68 to 12.63 kΩ. The simplicity in phase regulation of the present method and the superior optical and electrical properties of the films may allow its wide applications in thermo-opto-electro sensing devices.

  13. Haplotypes in the APOA1-C3-A4-A5 gene cluster affect plasma lipids in both humans and baboons

    SciTech Connect

    Wang, Qian-fei; Liu, Xin; O'Connell, Jeff

    2003-09-15

    Genetic studies in non-human primates serve as a potential strategy for identifying genomic intervals where polymorphisms impact upon human disease-related phenotypes. It remains unclear, however, whether independently arising polymorphisms in orthologous regions of non-human primates leads to similar variation in a quantitative trait found in both species. To explore this paradigm, we studied a baboon apolipoprotein gene cluster (APOA1/C3/A4/A5) for which the human gene orthologs have well established roles in influencing plasma HDL-cholesterol and triglyceride concentrations. Our extensive polymorphism analysis of this 68 kb gene cluster in 96 pedigreed baboons identified several haplotype blocks each with limited diversity, consistent withmore » haplotype findings in humans. To determine whether baboons, like humans, also have particular haplotypes associated with lipid phenotypes, we genotyped 634 well characterized baboons using 16 haplotype tagging SNPs. Genetic analysis of single SNPs, as well as haplotypes, revealed an association of APOA5 and APOC3 variants with HDL cholesterol and triglyceride concentrations, respectively. Thus, independent variation in orthologous genomic intervals does associate with similar quantitative lipid traits in both species, supporting the possibility of uncovering human QTL genes in a highly controlled non-human primate model.« less

  14. rAed a 4: A New 67-kDa Aedes aegypti Mosquito Salivary Allergen for the Diagnosis of Mosquito Allergy.

    PubMed

    Peng, Zhikang; Caihe, Li; Beckett, Andrew N; Guan, Qingdong; James, Anthony A; Simons, F Estelle R

    2016-01-01

    Accurate diagnosis of mosquito allergy has been hampered by the laborious task of obtaining mosquito salivary allergens. We have previously studied 3 recombinant (r) Aedes aegypti mosquito salivary allergens: rAed a 1, rAed a 2 and rAed a 3. Here, we report the expression, purification, identification and evaluation of rAed a 4, a 67-kDa α-glucosidase. rAed a 4 was expressed using a baculovirus/insect cell system, purified by a combination of anion- and cation-exchange chromatography, and identified by immunoblotting. A. aegypti saliva extract was prepared in our laboratory. An indirect enzyme-linked immunosorbent assay (ELISA) was developed to measure rAed a 4-specific immunoglobulin E (IgE) and IgG antibodies in sera from 13 individuals with a positive mosquito-bite test from a laboratory-reared mosquito. Sera from 18 individuals with a negative bite test served as controls. Purified rAed a 4 bound to the IgE in mosquito-allergic sera, as detected by ELISA and immunoblotting. The binding of rAed a 4 to IgE could be inhibited in a dose-dependent manner by the addition of an A. aegypti extract. Mosquito-allergic individuals had significantly higher mean levels of rAed a 4-specific IgE and IgG than controls. Using the mean of the controls ± 2 SD as a cut-off level, 46% of the 13 allergic individuals had a positive IgE, while none of the controls was positive (p < 0.001). Aed a 4 is a major allergen in mosquito saliva. Its recombinant form has the hydrolase function and can be used for the diagnosis of mosquito allergy. © 2016 S. Karger AG, Basel.

  15. Molecules based on M(v) (M=Mo, W) and Ni(II) ions: a new class of trigonal bipyramidal cluster and confirmation of SMM behavior for the pentadecanuclear molecule {NiII[NiII(tmphen)(MeOH)]6[Ni(H2O)3]2[micro-CN]30[WV(CN)3]6}.

    PubMed

    Hilfiger, Matthew G; Zhao, Hanhua; Prosvirin, Andrey; Wernsdorfer, Wolfgang; Dunbar, Kim R

    2009-07-14

    The preparation, single crystal X-ray crystallography, and magnetic properties are reported for four new clusters based on [M'V(CN)8]3- octacyanometallates (M'=Mo, W). Reactions of [M'V(CN)8]3- with mononuclear NiII ions in the presence of the tmphen blocking ligand (tmphen=3,4,7,8-tetramethyl-1,10-phenanthroline) in a 2:3:6 ratio, respectively, lead to the formation of the trigonal bipyramidal clusters [NiII(tmphen)2]3[M'V(CN)8]2. Analogous reactions with the same starting materials performed in a 2:3:2 ratio, respectively, produce pentadecanuclear clusters of the type {NiII[NiII(tmphen)(MeOH)]6[Ni(H2O)3]2[micro-CN]30[WV(CN)3]6}. The W2Ni3 (1) and Mo2Ni3(2) pentanuclear clusters and the W6Ni9 (3) and Mo6Ni9 (4) pentadecanuclear molecules are isostructural to each other and crystallize in the space groups P2(1)/c and R3 respectively. Magnetic measurements indicate that the ground states for the trigonal bipyamidal clusters are S=4 as a consequence of ferromagnetic coupling with JW-Ni=9.5 cm(-1), JMo-Ni=10 cm(-1). The pentadecanuclear clusters exhibit ferromagnetic coupling as well, which leads to S=12 ground states (JW-Ni=12 cm(-1), JMo-Ni=12.2 cm(-1)). Reduced magnetization studies on the W-Ni analogues support the conclusion that they exhibit a negative axial anisotropy term; the fits give D values of -0.24 cm(-1) for the W2Ni3 cluster and D=-0.04 cm(-1)for the W6Ni9 cluster. AC susceptibility measurements indicate the beginning of an out-of-phase signal for the W2Ni3 and the W6Ni9 compounds, but detailed low temperature studies on small crystals by the microSQUID technique indicate that only the pentadecanuclear cluster exhibits hysteresis in accord with SMM behavior. Neither Mo cluster reveals any evidence for slow paramagnetic relaxation at low temperatures.

  16. Responses of flocculus and vestibular nuclei neurons in Weaver mutant mice (B6CBA wv/wv) to combined head and body rotation.

    PubMed

    Grüsser-Cornehls, U

    1995-01-01

    The responses of vestibular nuclei (Vn) neurons and floccular Purkinje (P) cells to natural stimulation of the horizontal canals were recorded in paralyzed Weaver mutant mice. The Weaver mice suffer from an almost complete postnatal degeneration of granule cells and a portion of the P cells (Sidman et al. 1965). Parallel fibers are never elaborated (Bradley and Berry 1978). Recording sites were localized by means of small, iontophoretically applied HRP markings. Phase and sensitivity were analyzed by a Fourier analysis and a "best sine fitting" program. As in the normal "control" mice (Grüsser-Cornehls et al. 1995), the "simple spike" discharges of Vn and P cells in Weaver mutant mice are modulated sinusoidally upon sinusoidal stimulation. The neuronal response amplitude at fundamental frequency (determined from peristimulus time histograms, PSTHs increased with frequency (0.05-0.5 Hz) for both Vn and floccular neurons. The stimulus frequency/response amplitude and sensitivity (re velocity) curves for floccular neurons are distinctly lower in magnitude than those of Vn neurons (P < 0.01). In our sample of neurons, the Vn neurons curves of the mutants display a remarkable be behavior: the mean value curve of type I neurons is shifted upward, indicating a loss of inhibition but that of type II, downward, demonstrating a downregulation in comparison with the control values. The difference between the two curves is statistically significant (P < 0.001). The mean value curve of all mutant Vn neurons depends on the different fractions of type I and type II neurons in the sample investigated. In our investigations, the mean value curves of both type I and type II neurons also exceed those of the normal controls. The phase shift relative to head angular velocity in the midfrequency range in Vn neurons was very similar to that in normal controls, but the phase advance in the range of 0.3-0.5 Hz was somewhat larger and the SD larger over the whole range tested. Concerning the phase relationship for floccular neurons, a major difference occurred in contrast to the normal controls: the phase lead and phase lag varied from neurons to neuron, in individual neurons from frequency to frequency, and in some neurons distinctly from trial to trail. It is hypothesized that an intact mossy fiber-granule cell-parallel fiber system plays an important role in an orderly information flow, transmitted through the P-cell axons, and that the morphological disruption has implications for target cell activity. There is a strong suggestion that the diverse behavior of type I and type II neurons in the Vn may have implications for the poor motor performance in Weaver mutant mice.

  17. Development of a new fluorescent probe: 1,3,5,7-tetramethyl-8-(4'-aminophenyl)-4,4-difluoro-4-bora-3a,4a-diaza- s-indacence for the determination of trace nitrite

    NASA Astrophysics Data System (ADS)

    Li, Mengling; Wang, Hong; Zhang, Xian; Zhang, Hua-shan

    2004-03-01

    A new fluorescent probe, 1,3,5,7-tetramethyl-8-(4'-aminophenyl)-4,4-difluoro-4-bora-3a,4a-diaza- s-indacence (TMABODIPY) has been developed for the determination of trace nitrite in terms of the reaction of nitrite with TMABODIPY first in acidic solution and then in alkaline solution to form diazotate, a stable and highly fluorescent reagent. The method offered the advantage of specificity, sensitivity and simplicity. The linear calibration range for nitrite was 8-300 nmol l -1 s with a 3 σ detection limit of 0.65 nmol l -1. The proposed method has been applied to monitor the trace nitrite in drinking water and vegetable without extraction.

  18. Stratigraphic comparison of six oil fields (WV) producing from Big Injun sandstones

    SciTech Connect

    Zou, X.; Donaldson, A.C.

    1993-08-01

    Clustered within western West Virginia, six oil fields produce from the lower Mississippian Big Injun sandstones, and three more oil fields also supplement this production either from underlying Squaw or Weir sandstones. Shales separate these sandstones that occur stratigraphically between the Sunbury Shale (maximum flooding surface) and pre-Greenbrier unconformity (maximum regressive erosional surface), and represent highstand regressive deposits associated with the postorogenic phase of foreland basin accumulation. Stratigraphic studies show two Big Injun sandstones. The upper sandstone, called the Maccrady Big Injun, is separated from the lower Price/Pocono Big Injun sandstone by red shales. Both Big Injun sandstones consist ofmore » fine-grained river-mouth bars capped by coarse-grained river-channel deposits. Although the six fields are within three adjacent counties, Maccrady Big Injun sandstones of Blue Creek (Kanawha) and Rock Creek (Roane) fields are younger and were deposited by a different fluvial-deltaic system than the Price/Pocono Big Injun sandstones of Granny Creek (Clay), Tariff (Roane) Clendenin (Clay), and Pond Fork (Kanawha) fields. Upper Weir sandstones are thick, narrow north-trending belts underlying Pond Fork and Blue Creek fields, with properties suggesting wave-dominated shoreline deposits. Allocycles spanning separate drainage systems indicate eustasy. Postorogenic flexural adjustments probably explain stacked sandstone belts with superposed paleovalleys of overlying unconformities (pre-Greenbrier, Pottsville), particularly where aligned along or parallel basement structures of Rome trough or West Virginia dome. Initially, differential subsidence or uplift during sedimentation influenced the position, geometry, trend, and distribution patterns of these reservoir sandstone, then influenced their preserved condition during erosion of pre-Greenbrier unconformity.« less

  19. WV Kids Count Data Book: 1992 County Profiles of Child Well-Being.

    ERIC Educational Resources Information Center

    West Virginia Task Force on Children, Youth and Families, Charleston.

    In order to document the economic, social, educational, and emotional status and physical well-being of children in West Virginia, this databook provides national and state profiles, a separate minority profile, and 55 county profiles. For the state and each county, 10-year (1980-90) trend data are presented for 12 indicators: child abuse/neglect…

  20. 75 FR 56469 - Safety Zone; Ohio River, Wheeling, WV, Wheeling Heritage Port Sternwheel Foundation Fireworks...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-16

    ... clicking ``Search.'' This material is also available for inspection or copying at the Docket Management... rule elsewhere in this preamble. Taking of Private Property This rule will not cause a taking of private property or otherwise have taking implications under Executive Order 12630, Governmental Actions...

  1. 75 FR 65525 - TRG Insurance Solutions, Beckley, WV; Notice of Revised Determination on Reconsideration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-25

    ... petitioners requested administrative reconsideration of the Department's negative determination regarding the... workers in the group threatened with total or partial separation from employment on date of certification...

  2. Kanawha State Forest, WV: Wildland fire fuel load assessment and geospatial distribution

    Treesearch

    Adele Fenwick; Jamie L. Schuler; Shawn Grushecky; Thomas M. Schuler; Melissa Thomas-Van Gundy

    2014-01-01

    Fire has become a major concern along the wildland-urban interface (WUI), and there is increased awareness that fires could result in serious damage to people and property in residential areas occurring in forested landscapes. Part of the long-term strategy the West Virginia Division of Forestry outlined in the 2010 West Virginia Statewide Forest Resource Assessment...

  3. 76 FR 64295 - Proposed Amendment of Class E Airspace; Huntington, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-18

    ... through the Internet at http://www.regulations.gov . FOR FURTHER INFORMATION CONTACT: John Fornito... the proposal. Communications should identify both docket numbers (FAA Docket No. FAA-2011-1057... ADDRESSES section for address and phone number). You may also submit comments through the Internet at http...

  4. 76 FR 40402 - Matthews International Corporation, Bronze Division, Kingwood, WV; Notice of Negative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-08

    ... the Federal Register on February 10, 2011 (76 FR 7584). Workers were engaged in the production of cast... their purchases of cast bronze memorial products (and like or directly competitive articles) in 2007... Department determines that imports of articles like or directly competitive with the cast bronze memorial...

  5. Characterization of Rain Attenuation and Depolarization at W/V Bands

    DTIC Science & Technology

    2017-03-22

    attenuation and research into antennas that operate at these frequencies are in relative infancy compared to the more commonly used bands. This effort...atmospheric attenuation and research into antennas that operate at these frequencies are in relative infancy compared to the more commonly used bands...UNLIMITED. AIR FORCE RESEARCH LABORATORY Space Vehicles Directorate 3550 Aberdeen Ave SE AIR FORCE MATERIEL COMMAND KIRTLAND AIR FORCE BASE, NM 87117

  6. 78 FR 8589 - Verizon Services Corporation, Customer Services Clerk, General Clerk, Clarksburg, WV; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-06

    ... Department of Labor (Department) on January 4, 2013, workers of Verizon Services Corporation, Customer... reconsideration of the negative determination regarding workers' eligibility to apply for Trade Adjustment Assistance (TAA) applicable to workers and former workers of the subject firm. The Department's determination...

  7. WV R-EMAP STUDY: MULTIPLE-OBJECTIVE SAMPLING DESIGN FRAMEWORK

    EPA Science Inventory

    A multi-objective sampling design has been implemented through Regional Monitoring and Assessment Program (R-EMAP) support of a cooperative agreement with the state of West Virginia. Goals of the project include: 1) development and testing of a temperature-adjusted fish IBI for t...

  8. 77 FR 16544 - City of New Martinsville, WV; Notice of Petition for Enforcement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-21

    ... 210(h)(2)(B) of the Public Utility Regulatory Policies Act of 1978 (PURPA), the City of New... such other relief as the Commission may deem proper in order to remedy the PSC's violations of PURPA...

  9. 76 FR 12365 - Canaan Valley National Wildlife Refuge, Tucker and Grant Counties, WV; Final Comprehensive...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-07

    ... protect fish and wildlife resources and the unique wetland and upland habitats of this high-elevation... acres. It includes the largest wetland complex in the State, and encompasses the headwaters of the... integrity of the Canaan Valley wetland complex, perpetuating the ecological integrity of upland northern...

  10. 78 FR 3964 - Request for Public Comment, Raleigh County Memorial Airport, Beckley, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-17

    ... released, the land will be sold and placed in a Conservation Easement, with restriction of no future development. Proposed buyer would be placing the area of request in a conservation easement for wildlife... is not needed for airport development as shown on the Airport Layout Plan. Fair Market Value has been...

  11. 77 FR 38376 - Request for Public Comment, Raleigh County Memorial Airport, Beckley, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-27

    ... land will be sold and placed in a Conservation Easement, with restriction of no future development. Proposed buyer would be placing the area of request in a conservation easement for wildlife enhancement... needed for airport development as shown on the Airport Layout Plan. Fair Market Value has been determined...

  12. Proceedings of the Third International Workshop on Multistrategy Learning, May 23-25 Harpers Ferry, WV.

    DTIC Science & Technology

    1996-09-16

    approaches are: • Adaptive filtering • Single exponential smoothing (Brown, 1963) * The Box-Jenkins methodology ( ARIMA modeling ) - Linear exponential... ARIMA • Linear exponential smoothing: Holt’s two parameter modeling (Box and Jenkins, 1976). However, there are two approach (Holt et al., 1960) very...crucial disadvantages: The most important point in - Winters’ three parameter method (Winters, 1960) ARIMA modeling is model identification. As shown in

  13. Characterization of Rain Attenuation and Depolarization at W/V Bands

    DTIC Science & Technology

    2015-07-30

    AIR FORCE BASE , NM 87117-5776 DTIC COPY NOTICE AND SIGNATURE PAGE Using Government drawings, specifications, or other data included in this...WITH ASSIGNED DISTRIBUTION STATEMENT. //SIGNED// //SIGNED// STEVEN A. LANE PAUL HAUSGEN, Ph.D. Program Manager Technical Advisor, Space Based Advanced... Stations ........................................................................................ 11  Figure 3. Transmitter Block Diagram

  14. 75 FR 63540 - Request for Public Comment, Morgantown Municipal Airport, Morgantown, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... delivered to Dan Boroff, City Manager of the City of Morgantown, Sponsor of Morgantown Municipal Airport at the following address: Dan Boroff, City Manager, City of Morgantown, Sponsor for Morgantown Municipal...

  15. WV R-EMAP SMALL WATERSHED CHARACTERIZATION, CLASSIFICATION, AND ASSESSMENT FOR WEST VIRGINIA UTILIZING EMAP DESIGN AND TOOLS

    EPA Science Inventory

    A probabilistic watershed-based framework was developed to encompass wadeable streams within all three ecoregions of West Virginia, with the exclusion noted below. In Phase I of the project (year 2001), we developed and applied a probabilistic watershed-based sampling framework ...

  16. Effects of a Culturally Responsive Teaching Project on Teachers and Students in Selected Kanawha County, WV, Schools

    ERIC Educational Resources Information Center

    Hughes, Georgia K.; Cowley, Kimberly S.; Copley, Lisa D.; Finch, Nicole L.; Meehan, Merrill L.; Burns, Rebecca C.; Kusimo, Patricia S.; Keyes, Marian C.; Orletsky, Sandra R.; Holdzkom, David

    2004-01-01

    Differences in academic achievement among ethnic and socioeconomic groups, called achievement gaps, have been an issue in education for many years. Achievement gaps exist between upper- and lower-class students and between students of differing races and ethnic backgrounds. As a group, Black and Hispanic students perform less well on many…

  17. An Evaluation of the Merit Reading Software Program in the Calhoun County (WV) Middle/High School

    ERIC Educational Resources Information Center

    Jones, Jerry D.; Staats, William D.; Bowling, Noel; Bickel, Robert D.; Cunningham, Michael L.; Cadle, Connie

    2005-01-01

    We were asked by Merit Software to conduct a quasi-experimental research study to evaluate the effects of its reading software on middle school students. Because the No Child Left Behind Act emphasizes the importance of evidence-based interventions and has set improving students reading comprehension as a goal, we agreed to take on this project.…

  18. 75 FR 47715 - Safety Zone; Kanawha River Mile 56.7 to 57.6, Charleston, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-09

    ... implications under Executive Order 12630, Governmental Actions and Interference with Constitutionally Protected... fits this category because the Coast Guard is establishing a safety zone from mile 56.7 to 57.6 on the...

  19. The response of tree ring δ15N to whole-watershed urea fertilization at the Fernow Experimental Forest, WV

    Treesearch

    Mark B. Burnham; Brenden E. McNeil; Mary Beth Adams; William T. Peterjohn

    2016-01-01

    Plant tissue δ15N is frequently used as a proxy for N availability and N cycle dynamics, and the δ15N signature of tree rings could potentially be used to reconstruct past changes in the N cycle due to forest disturbance or anthropogenic N deposition. However, there are substantial uncertainties regarding how effectively...

  20. Evaluating reclamation success: the ecological consideration-proceedings of a symposium; 1990 April 23-26; Charleston, WV.

    Treesearch

    Jeanne C. Chambers; Gary L. Wade; [Editors

    1992-01-01

    Includes 10 papers from a symposium organized to review what is know about the ecological principles that will govern the ultimate success or failure of all reclamation efforts on drastically disturbed lands. The papers cover four general areas: soil biological properties and nutrient cycling; vegetation dynamics; animal recolinization; and landscape-scale processes...

  1. Superfund record of decision (EPA Region 3): Allegany Ballistics Laboratory (USNavy) Site 10, Mineral, WV, June 30, 1998

    SciTech Connect

    NONE

    1998-12-01

    This decision document presents the selected remedial action for Site 10 (the Site) Groundwater at the Allegany Ballistics Laboratory (ABL), Rocket Center, West Virginia. The major components of the selected remedy are: Institutional controls, including land use restrictions imposed through appropriate administrative mechanisms to prevent groundwater use; Groundwater pumping from a minimum of three extraction wells to capture the hot spot of the VOC contaminant plume; Installation of a pipeline to transport groundwater from Site 10 to the Site 1 treatment plant; Discharge to the North Branch Potomac River; and Groundwater monitoring on a timely basis, quarterly to semi-annually, willmore » evaluate groundwater quality, contaminant migration, and degradation for inclusion in the 5-year site reviews.« less

  2. Superfund Record of Decision (EPA Region 3): Allegany Ballistics Laboratory (USNavy), Operable Unit 1, Mineral, WV, February 12, 1997

    SciTech Connect

    NONE

    1998-01-01

    This decision document presents the selected remedial action for Site 5 Landfill Contents and Surface Soil at the Allegany Ballistics Laboratory (ABL), Rocket Center, West Virginia. The major components of the selected remedy are: Deed notation along with property use and limited access restrictions; Installation of a composite CAP-GCL and FMC; Installation of a drainage layer utilizing a geonet; Installation of a passive landfill gas (LFG) venting system; Revegetation of the capped area; Installation of perimeter drainage system; and Post-closure requirements.

  3. 75 FR 1806 - Draft General Management Plan and Environmental Impact Statement, New River Gorge National River, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-13

    ... DEPARTMENT OF THE INTERIOR National Park Service Draft General Management Plan and Environmental... Interior. ACTION: Notice of availability of the Draft General Management Plan and Environmental Impact...

  4. 76 FR 13354 - Foreign-Trade Zone 229-Charleston, WV; Application for Subzone; Cabela's Inc.; (Hunting, Fishing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-11

    ..., boating, camping, pet and related products (duty rate ranges from duty-free to 48%). FTZ procedures could...'s to realize logistical benefits through the use of weekly customs entry procedures. The request...

  5. An application for impedance spectroscopy in the characterisation of the glass transition during the lyophilization cycle: the example of a 10% w/v maltodextrin solution.

    PubMed

    Smith, Geoff; Arshad, Muhammad Sohail; Polygalov, Eugene; Ermolina, Irina

    2013-11-01

    Impedance spectroscopy has been used for the measurement of the glass transition of a 10 % maltodextrin solution contained within a glass vial, with externally attached electrodes. Features of the pseudo-relaxation process, associated with the composite impedance of the glass vial-solution assembly, were characterised by the peak amplitude, C(peak)(″), and peak frequency, f(peak), of the capacitance spectra and the equivalent circuit elements that model the impedance spectra (i.e. the solution resistance and solution capacitance) and monitored every 3 min during re-heating of the solution. The time derivatives of all four parameters studied provided a glass transition in close agreement with DSC measurements (-17 °C) and at a precision of ± 0.5 °C. The temperature dependencies of the solution resistance and peak frequency were then characterised with the Arrhenius and Vogel-Fulcher-Tammann fit functions, at temperatures below and above Tg, respectively. The energy of activation (below Tg) was estimated at ~20 kJ mol(-1), and the fragility index (If) of the glass forming liquid (above Tg) was estimated at 0.9. The significance of the fragility index to the development, optimisation and control of the freeze-drying cycle is highlighted. Copyright © 2013 Elsevier B.V. All rights reserved.

  6. A watershed-based spatially-explicit demonstration of an integrated environmental modeling framework for ecosystem services in the Coal River Basin (WV, USA)

    Treesearch

    John M. Johnston; Mahion C. Barber; Kurt Wolfe; Mike Galvin; Mike Cyterski; Rajbir Parmar; Luis Suarez

    2016-01-01

    We demonstrate a spatially-explicit regional assessment of current condition of aquatic ecoservices in the Coal River Basin (CRB), with limited sensitivity analysis for the atmospheric contaminant mercury. The integrated modeling framework (IMF) forecasts water quality and quantity, habitat suitability for aquatic biota, fish biomasses, population densities, ...

  7. RETROFIT COSTS FOR SO2 AND NOX CONTROL OPTIONS AT 200 COAL-FIRED PLANTS, VOLUME V - SITE SPECIFIC STUDIES FOR PA, SC, TN, VA, WI, WV

    EPA Science Inventory

    The report gives results of a study, the objective of which was to significantly improve engineering cost estimates currently being used to evaluate the economic effects of applying SO2 and NOx controls at 200 large SO2-emitting coal-fired utility plants. To accomplish the object...

  8. A Watershed-based spatially-explicit demonstration of an Integrated Environmental Modeling Framework for Ecosystem Services in the Coal River Basin (WV, USA)

    EPA Science Inventory

    We demonstrate a spatially-explicit regional assessment of current condition of aquatic ecoservices in the Coal River Basin (CRB), with limited sensitivity analysis for the atmospheric contaminant mercury. The integrated modeling framework (IMF) forecasts water quality and quant...

  9. Fifty years of watershed research on the Fernow Experimental Forest, WV: effects of forest management and air pollution on hardwood forests

    Treesearch

    M.B. Adams; P.J. Edwards; J.N. Kochenderfer; F. Wood

    2004-01-01

    In 1951, stream gaging was begun on five small headwater catchments on the Fernow Experimental Forest in West Virginia, to study the effects of forest management activities, particularly timber harvesting, on water yield and quality. Results from these watersheds, and others gaged more recently, have shown that annual water yields increase in proportion to the basal...

  10. Lipoxin A4, a 5-lipoxygenase pathway metabolite, modulates immune response during acute respiratory tularemia.

    PubMed

    Singh, Anju; Rahman, Tabassum; Bartiss, Rose; Arabshahi, Alireza; Prasain, Jeevan; Barnes, Stephen; Musteata, Florin Marcel; Sellati, Timothy J

    2017-02-01

    Respiratory infection with Francisella tularensis (Ft) is characterized by a muted, acute host response, followed by sepsis-like syndrome that results in death. Infection with Ft establishes a principally anti-inflammatory environment that subverts host-cell death programs to facilitate pathogen replication. Although the role of cytokines has been explored extensively, the role of eicosanoids in tularemia pathogenesis is not fully understood. Given that lipoxin A 4 (LXA 4 ) has anti-inflammatory properties, we investigated whether this lipid mediator affects host responses manifested early during infection. The addition of exogenous LXA 4 inhibits PGE 2 release by Ft-infected murine monocytes in vitro and diminishes apoptotic cell death. Tularemia pathogenesis was characterized in 5‑lipoxygenase-deficient (Alox5 -/- ) mice that are incapable of generating LXA 4 Increased release of proinflammatory cytokines and chemokines, as well as increased apoptosis, was observed in Alox5 -/- mice as compared with their wild-type counterparts. Alox5 -/- mice also exhibited elevated recruitment of neutrophils during the early phase of infection and increased resistance to lethal challenge. Conversely, administration of exogenous LXA 4 to Alox5 -/- mice made them more susceptible to infection thus mimicking wild-type animals. Taken together, our results suggest that 5-LO activity is a critical regulator of immunopathology observed during the acute phase of respiratory tularemia, regulating bacterial burden and neutrophil recruitment and production of proinflammatory modulators and increasing morbidity and mortality. These studies identify a detrimental role for the 5-LO-derived lipid mediator LXA 4 in Ft-induced immunopathology. Targeting this pathway may have therapeutic benefit as an adjunct to treatment with antibiotics and conventional antimicrobial peptides, which often have limited efficacy against intracellular bacteria. © Society for Leukocyte Biology.

  11. 75 FR 24790 - IFR Altitudes; Miscellaneous Amendments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-06

    ... Read in Part *Italy, WV FIX REACH, WV FIX 4000 *4000-MRA Reach, WV FIX ELKINS, WV VORTAC....... 4400...-MOCA Cleep, TX FIX *Legge, TX FIX 3100 *3000-MRA Napoleon, MO VORTAC LAMONI, IA VORTAC....... 2900 Sec... in Part Sacky, WV FIX *Julea, WV FIX 3000 *5000-MRA *Julea, WV FIX Benzo, WV FIX 3300 *5000-MRA Benzo...

  12. Polyfluoroalkyl substance exposure in the Mid-Ohio River Valley, 1991-2012.

    PubMed

    Herrick, Robert L; Buckholz, Jeanette; Biro, Frank M; Calafat, Antonia M; Ye, Xiaoyun; Xie, Changchun; Pinney, Susan M

    2017-09-01

    Industrial discharges of perfluorooctanoic acid (PFOA) to the Ohio River, contaminating water systems near Parkersburg, WV, were previously associated with nearby residents' serum PFOA concentrations above US general population medians. Ohio River PFOA concentrations downstream are elevated, suggesting Mid-Ohio River Valley residents are exposed through drinking water. Quantify PFOA and 10 other per- and polyfluoroalkyl substances (PFAS) in Mid-Ohio River Valley resident sera collected between 1991 and 2013 and determine whether the Ohio River and Ohio River Aquifer are exposure sources. We measured eleven PFAS in 1608 sera from 931 participants. Serum PFOA concentration and water source associations were assessed using linear mixed-effects models. We estimated between-sample serum PFOA using one-compartment pharmacokinetics for participants with multiple samples. In serum samples collected as early as 1991, PFOA (median = 7.6 ng/mL) was detected in 99.9% of sera; 47% had concentrations greater than US population 95th percentiles. Five other PFAS were detected in greater than 82% of samples; median other PFAS concentrations were similar to the US general population. Serum PFOA was significantly associated with water source, sampling year, age at sampling, tap water consumption, pregnancy, gravidity and breastfeeding. Serum PFOA was 40-60% lower with granular activated carbon (GAC) use. Repeated measurements and pharmacokinetics suggest serum PFOA peaked 2000-2006 for participants using water without GAC treatment; where GAC was used, serum PFOA concentrations decreased from 1991 to 2012. Mid-Ohio River Valley residents appear to have PFOA, but not other PFAS, serum concentrations above US population levels. Drinking water from the Ohio River and Ohio River Aquifer, primarily contaminated by industrial discharges 209-666 km upstream, is likely the primary exposure source. GAC treatment of drinking water mitigates, but does not eliminate, PFOA exposure. Copyright

  13. 36 CFR Appendix B to Part 72 - List of Eligible Jurisdictions

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Jersey East Providence, Rhode Island East St. Louis, Illinois Easton, Pennsylvania Edinburg, Texas El... Jackson, Mississippi Jackson, Tennessee Jacksonville, Florida Jersey City, New Jersey Johnson City... Parkersburg, West Virginia Pasco, Washington Passaic, New Jersey Paterson, New Jersey Pawtucket, Rhode Island...

  14. 36 CFR Appendix B to Part 72 - List of Eligible Jurisdictions

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Jersey East Providence, Rhode Island East St. Louis, Illinois Easton, Pennsylvania Edinburg, Texas El... Jackson, Mississippi Jackson, Tennessee Jacksonville, Florida Jersey City, New Jersey Johnson City... Parkersburg, West Virginia Pasco, Washington Passaic, New Jersey Paterson, New Jersey Pawtucket, Rhode Island...

  15. 36 CFR Appendix B to Part 72 - List of Eligible Jurisdictions

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Jersey East Providence, Rhode Island East St. Louis, Illinois Easton, Pennsylvania Edinburg, Texas El... Jackson, Mississippi Jackson, Tennessee Jacksonville, Florida Jersey City, New Jersey Johnson City... Parkersburg, West Virginia Pasco, Washington Passaic, New Jersey Paterson, New Jersey Pawtucket, Rhode Island...

  16. 36 CFR Appendix B to Part 72 - List of Eligible Jurisdictions

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Jersey East Providence, Rhode Island East St. Louis, Illinois Easton, Pennsylvania Edinburg, Texas El... Jackson, Mississippi Jackson, Tennessee Jacksonville, Florida Jersey City, New Jersey Johnson City... Parkersburg, West Virginia Pasco, Washington Passaic, New Jersey Paterson, New Jersey Pawtucket, Rhode Island...

  17. 36 CFR Appendix B to Part 72 - List of Eligible Jurisdictions

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Jersey East Providence, Rhode Island East St. Louis, Illinois Easton, Pennsylvania Edinburg, Texas El... Jackson, Mississippi Jackson, Tennessee Jacksonville, Florida Jersey City, New Jersey Johnson City... Parkersburg, West Virginia Pasco, Washington Passaic, New Jersey Paterson, New Jersey Pawtucket, Rhode Island...

  18. 76 FR 43634 - Approval and Promulgation of Air Quality Implementation Plans; West Virginia and Ohio...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-21

    ... 1997 Annual Fine Particle Standard for the Parkersburg-Marietta and Wheeling Nonattainment Areas AGENCY... fine particle (PM 2.5 ) nonattainment areas (hereafter referred to as ``Areas'') have attained the 1997...

  19. 31 CFR 351.2 - How do I contact Fiscal Service?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Service by e-mail at [email protected]gov, or by writing to the following address: Bureau of the Fiscal Service, Parkersburg, West Virginia 26106-1328. Our website address is www.savingsbonds.gov. ...

  20. 76 FR 7906 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-11

    ... designated to act on behalf of the organization. Respondents: Private sector: Business or other for-profit..., 200 Third Street, Parkersburg, West Virginia 26106; (304) 480-8112. OMB Reviewer: Shagufta Ahmed...

  1. 76 FR 20450 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-12

    ... participate in U.S. Treasury Securities Auctions via TAPPS Link. Affected Public: Private Sector: Businesses... of the Public Debt, 200 Third Street, Parkersburg, West Virginia 26106; (304) 480-8112. OMB Reviewer...

  2. Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides.

    PubMed

    Talmud, Philippa J; Hawe, Emma; Martin, Steve; Olivier, Michael; Miller, George J; Rubin, Edward M; Pennacchio, Len A; Humphries, Steve E

    2002-11-15

    Since triglycerides (TG) are a major independent risk factor for coronary heart disease, understanding their genetic and environmental determinants is of major importance. Mouse models indicate an inverse relationship between levels of the newly identified apolipoprotein AV (APOAV) and TG concentrations. We have examined the relative influence of human APOA5 variants on plasma lipids, compared to the impact of variation in APOC3 and APOA4 which lie in the same cluster. Single nucleotide polymorphisms (SNPs) in APOA5 (S19W, -1131T>C) and APOA4 (T347S, Q360H) and an APOA4/A5 intergenic T>C SNP were examined in a large study of healthy middle-aged men (n=2808). APOA5 19WW and -1131CC men had 52% and 40% higher TG (P<0.003) compared to common allele homozygotes, respectively, effects which were independent and additive. APOA4 347SS men had 23% lower TG compared to TT men (P<0.002). Haplotype analysis was carried out to identify TG-raising alleles and included, in addition, four previously genotyped APOC3 SNPs (-2845T>G, -482C>T, 1100C>T, and 3238C>G). The major TG-raising alleles were defined by APOA5 W19 and APOC3 -482T. This suggests that the TG-lowering effect of APOA4 S347 might merely reflect the strong negative linkage disequilibrium with the common alleles of these variants. Thus variation in APOA5 is associated with differences in TGs in healthy men, independent of those previously reported for APOC3, while association between APOA4 and TG reflects linkage disequilibrium with these sites. The molecular mechanisms for these effects remain to be determined.

  3. Sulfur K-edge XAS of WV=O vs. MoV=O Bis(dithiolene) Complexes: Contributions of Relativistic Effects to Electronic Structure and Reactivity of Tungsten Enzymes†

    PubMed Central

    Tenderholt, Adam L.; Szilagyi, Robert K.; Holm, Richard H.; Hodgson, Keith O.; Hedman, Britt; Solomon, Edward I.

    2009-01-01

    Molybdenum- or tungsten-containing enzymes catalyze oxygen atom transfer reactions involved in carbon, sulfur, or nitrogen metabolism. It has been observed that reduction potentials and oxygen atom transfer rates are different for W relative to Mo enzymes and the isostructural Mo/W complexes. Sulfur K-edge X-ray absorption spectroscopy (XAS) and density functional theory (DFT) calculations on [MoVO(bdt)2]− and [WVO(bdt)2]−, where bdt = benzene-1,2-dithiolate(2−), have been used to determine that the energies of the half-filled redox-active orbital, and thus the reduction potentials and M=O bond strengths, are different for these complexes due to relativistic effects in the W sites. PMID:17720249

  4. 26 CFR 1.170A-4A - Special rule for the deduction of certain charitable contributions of inventory and other property.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... contribution of women's coats which were section 1221(1) property. The fair market value of the property at the... section, and the donor's cost of goods sold for the year of contribution must be adjusted under paragraph... donor's deduction is reduced to the amount allowable under section 170 of the regulations thereunder...

  5. 26 CFR 1.170A-4A - Special rule for the deduction of certain charitable contributions of inventory and other property.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... function constituting the ground for the exemption of the organization to which the contribution is made...)(3). In general, the amount of the reduction is equal to one-half of the amount of gain (other than gain described in paragraph (d) of this section) which would not have been long-term capital gain if...

  6. 26 CFR 1.170A-4A - Special rule for the deduction of certain charitable contributions of inventory and other property.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... function constituting the ground for the exemption of the organization to which the contribution is made...)(3). In general, the amount of the reduction is equal to one-half of the amount of gain (other than gain described in paragraph (d) of this section) which would not have been long-term capital gain if...

  7. 26 CFR 1.170A-4A - Special rule for the deduction of certain charitable contributions of inventory and other property.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... function constituting the ground for the exemption of the organization to which the contribution is made...)(3). In general, the amount of the reduction is equal to one-half of the amount of gain (other than gain described in paragraph (d) of this section) which would not have been long-term capital gain if...

  8. The Effect of microRNAs in the Regulation of Human CYP3A4: a Systematic Study using a Mathematical Model

    NASA Astrophysics Data System (ADS)

    Wei, Zhiyun; Jiang, Songshan; Zhang, Yiting; Wang, Xiaofei; Peng, Xueling; Meng, Chunjie; Liu, Yichen; Wang, Honglian; Guo, Luo; Qin, Shengying; He, Lin; Shao, Fengmin; Zhang, Lirong; Xing, Qinghe

    2014-03-01

    CYP3A4 metabolizes more than 50% of the drugs on the market. The large inter-individual differences of CYP3A4 expression may contribute to the variability of human drug responses. Post-transcriptional regulation of CYP3A4 is poorly understood, whereas transcriptional regulation has been studied much more thoroughly. In this study, we used multiple software programs to predict miRNAs that might bind to CYP3A4 and identified 112 potentially functional miRNAs. Then a luciferase reporter system was used to assess the effect of the overexpression of each potentially functional miRNA in HEK 293T cells. Fourteen miRNAs that significantly decreased reporter activity were measured in human liver samples (N = 27) as candidate miRNAs. To establish a more effective way to analyze in vivo data for miRNA candidates, the relationship between functional miRNA and target mRNA was modeled mathematically. Taking advantage of this model, we found that hsa-miR-577, hsa-miR-1, hsa-miR-532-3p and hsa-miR-627 could significantly downregulate the translation efficiency of CYP3A4 mRNA in liver. This study used in silico, in vitro and in vivo methods to progressively screen functional miRNAs for CYP3A4 and to enhance our understanding of molecular events underlying the large inter-individual differences of CYP3A4 expression in human populations.

  9. Obsessive-compulsive disorder and the promoter region polymorphism (5-HTTLPR) in the serotonin transporter gene (SLC6A4): a negative association study in the Afrikaner population.

    PubMed

    Kinnear, Craig J.; Niehaus, Dana J. H.; Moolman-Smook, Johanna C.; du Toit, Pieter L.; van Kradenberg, Jeanine; Weyers, Jakobus B.; Potgieter, Annemarie; Marais, Vanessa; Emsley, Robin A.; Knowles, James A.; Corfield, Valerie A.; Brink, Paul A.; Stein, Dan J.

    2000-12-01

    A polymorphism (5-HTTLPR) in the promoter region of the serotonin transporter gene (SLC6A4) has been reported to have functional significance and to be associated with obsessive-compulsive disorder (OCD). However, other studies have generated confounding results. A study was undertaken to re-evaluate this association in subjects drawn from the relatively genetically homogeneous Afrikaner population of South Africa. Fifty-four OCD patients of Afrikaner descent and 82 ethnically matched control individuals were phenotyped and genotyped. No significant association was found between the distribution of the 5-HTTLPR genotypes at the SLC6A4 locus and OCD. A similar result (p = 0.108) was generated when a meta-analysis of the 5-HTTLPR polymorphism, combining the current study with a previously reported Caucasian group, was performed; the meta-study comprised 129 OCD patients and 479 control individuals. However, both studies lacked power. Therefore, evidence that variation in SLC6A4 plays a significant role in the development of OCD in the population groups studied is inconclusive. Future association studies in Caucasian populations may extend the power of such meta-analyses and assist in delineating the role of SLC6A4 in OCD.

  10. NBCe1 (SLC4A4) a potential pH Regulator in Enamel Organ Cells during Enamel Development in the Mouse

    PubMed Central

    Jalali, R; Guo, J; Zandieh-Doulabi, B; Bervoets, TJM; Paine, ML; Boron, W; Parker, M; Bijvelds, MJC; Medina, JF; DenBesten, PK; Bronckers, ALJJ

    2016-01-01

    During formation of dental enamel maturation-stage ameloblasts express ion-transporting transmembrane proteins. The SLC4 family of ion-transporters regulates intra- and extracellular pH in eukaryotic cells by co-transporting HCO3− with Na+. Mutation in SLC4A4 (coding for the Na+ bicarbonate co-transporter NBCe1) induces developmental defects in human and murine enamel. We hypothesized that NBCe1 in dental epithelium is engaged in neutralizing protons released during crystal formation in the enamel space. We immunolocalized NBCe1 protein in mouse wild-type dental epithelium and examined the effect of NBCe1-null mutation on enamel formation in mice. Ameloblasts expressed gene transcripts for NBCe1 isoforms B/D/C/E. In wild-type mice weak to moderate immunostaining for NBCe1 with antibodies that recognize isoforms A/B/D/E and isoform C was seen in ameloblasts in secretory stage, no or very low staining in early maturation-stage but moderately to high staining in late maturation-stage. The papillary layer showed the opposite pattern and immunostained prominently at early maturation-stage but gradually showed less staining at mid- and late maturation-stage. In NBCe1−/− mice ameloblasts were disorganized, the enamel thin and severely hypomineralized. Enamel organs of CFTR−/− and AE2a,b−/− mice (believed to be pH regulators in ameloblasts) contained higher levels of NBCe1 protein than wild-type mice. Our data show that expression of NBCe1 in ameloblast and papillary layer cell depends on developmental stage and possibly responds to pH changes. PMID:25012520

  11. Slc15a4, a gene required for pDC sensing of TLR ligands, is required to control persistent viral infection.

    PubMed

    Blasius, Amanda L; Krebs, Philippe; Sullivan, Brian M; Oldstone, Michael B; Popkin, Daniel L

    2012-09-01

    Plasmacytoid dendritic cells (pDCs) are the major producers of type I IFN in response to viral infection and have been shown to direct both innate and adaptive immune responses in vitro. However, in vivo evidence for their role in viral infection is lacking. We evaluated the contribution of pDCs to acute and chronic virus infection using the feeble mouse model of pDC functional deficiency. We have previously demonstrated that feeble mice have a defect in TLR ligand sensing. Although pDCs were found to influence early cytokine secretion, they were not required for control of viremia in the acute phase of the infection. However, T cell priming was deficient in the absence of functional pDCs and the virus-specific immune response was hampered. Ultimately, infection persisted in feeble mice. We conclude that pDCs are likely required for efficient T cell priming and subsequent viral clearance. Our data suggest that reduced pDC functionality may lead to chronic infection.

  12. 26 CFR 1.170A-4A - Special rule for the deduction of certain charitable contributions of inventory and other property.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., mental, or emotional well-being, as a result of poverty or temporary distress. Examples of needy persons... the victim of a natural disaster (such as fire or flood), a person who is the victim of a civil disaster (such as a civil disturbance), a person who is temporarily not self-sufficient as a result of a...

  13. The Effect of microRNAs in the Regulation of Human CYP3A4: a Systematic Study using a Mathematical Model

    PubMed Central

    Wei, Zhiyun; Jiang, Songshan; Zhang, Yiting; Wang, Xiaofei; Peng, Xueling; Meng, Chunjie; Liu, Yichen; Wang, Honglian; Guo, Luo; Qin, Shengying; He, Lin; Shao, Fengmin; Zhang, Lirong; Xing, Qinghe

    2014-01-01

    CYP3A4 metabolizes more than 50% of the drugs on the market. The large inter-individual differences of CYP3A4 expression may contribute to the variability of human drug responses. Post-transcriptional regulation of CYP3A4 is poorly understood, whereas transcriptional regulation has been studied much more thoroughly. In this study, we used multiple software programs to predict miRNAs that might bind to CYP3A4 and identified 112 potentially functional miRNAs. Then a luciferase reporter system was used to assess the effect of the overexpression of each potentially functional miRNA in HEK 293T cells. Fourteen miRNAs that significantly decreased reporter activity were measured in human liver samples (N = 27) as candidate miRNAs. To establish a more effective way to analyze in vivo data for miRNA candidates, the relationship between functional miRNA and target mRNA was modeled mathematically. Taking advantage of this model, we found that hsa-miR-577, hsa-miR-1, hsa-miR-532-3p and hsa-miR-627 could significantly downregulate the translation efficiency of CYP3A4 mRNA in liver. This study used in silico, in vitro and in vivo methods to progressively screen functional miRNAs for CYP3A4 and to enhance our understanding of molecular events underlying the large inter-individual differences of CYP3A4 expression in human populations. PMID:24594634

  14. 6. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #445511, 'Nursery Manager's Residence'), H. C. Frayer, July 1947. VIEW EAST. (see also historic photographs WV-237-12, WV-237-13, WV-237-26) - Parsons Nursery, Manager's Residence, South side of U.S. Route 219, Parsons, Tucker County, WV

  15. 1. VIEW EAST, SEED EXTRACTOR BUILDING ON LEFT, IMPLEMENT BUILDING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. VIEW EAST, SEED EXTRACTOR BUILDING ON LEFT, IMPLEMENT BUILDING ON RIGHT. (see also WV-237-5, WV-237-9, WV-237-h-1, WV-237-L-1) - Parsons Nursery, Seed Extractor Building, South side of U.S. Route 219, Parsons, Tucker County, WV

  16. 78 FR 65212 - Suspension of Community Eligibility

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-31

    ... adopt and administer local floodplain management measures aimed at protecting lives and new construction... Relief and Emergency Assistance Act not in connection with a flood) may be provided for construction or...; November 6, 2013, Susp West Virginia: Parkersburg, City of, Wood 540214 July 1, 1974, ......* do Do. County...

  17. 78 FR 53275 - Approval and Promulgation of Air Quality Implementation Plans; Ohio; Redesignation of the Ohio...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-29

    ... dioxide (SO 2 ), ammonia and volatile organic compounds (VOC) in the Parkersburg-Marietta area (Washington... provided ammonia and VOC emissions inventories to EPA to supplement the February 29, 2012, and April 16... addition, EPA is approving the 2005 NO X , SO 2 , and PM 2.5 emission inventories and 2007/2008 ammonia and...

  18. Model Programs: Childhood Education. Project PLAN.

    ERIC Educational Resources Information Center

    American Institutes for Research in the Behavioral Sciences, Palo Alto, CA.

    This booklet is one of 34 in a series of programs on childhood education prepared for the White House Conference on Children. In Parkersburg, West Virginia, Project PLAN (Program for Learning in Accordance with Needs) offers an individualized instructional system designed to enable each student to progress at his own rate, using the learning…

  19. 76 FR 57013 - Approval and Promulgation of Air Quality Implementation Plans; West Virginia; Revised Motor...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-15

    ... Promulgation of Air Quality Implementation Plans; West Virginia; Revised Motor Vehicle Emission Budgets for the... Implementation Plan (SIP) revision submitted by the State of West Virginia for the purpose of amending the 8-hour ozone maintenance plan for the Charleston, Huntington, Parkersburg, Weirton, and Wheeling 8-hour ozone...

  20. Increasing Institutional Effectiveness: A Continuous Effort after Accreditation.

    ERIC Educational Resources Information Center

    Chen, HongYu

    West Virginia University at Parkersburg (WVUP) is a separately accredited campus of the University offering 2 baccalaureate, 10 associate, and 2 certificate programs. In response to concerns raised in a recent accreditation report, WVUP conducted a study examining student attitudes toward facilities, course scheduling, student advising,…

  1. 76 FR 79539 - Approval and Promulgation of Air Quality Implementation Plans; West Virginia; Revised Motor...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-22

    ... ENVIRONMENTAL PROTECTION AGENCY 40 CFR Part 52 [FDMS Docket No. EPA-R03-OAR-2011-0511; FRL-9609-1... Maintenance Areas; Correction AGENCY: Environmental Protection Agency (EPA). ACTION: Direct final rule..., Parkersburg, Weirton, and Wheeling 8-hour ozone maintenance areas. The previous rulemaking amended the...

  2. 31 CFR 361.7 - Report of loss, destruction or damage.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) FISCAL SERVICE, DEPARTMENT OF THE TREASURY BUREAU OF THE PUBLIC DEBT CLAIMS PURSUANT TO THE GOVERNMENT... the Bureau of the Public Debt, Division of Financial Management, Room 201, P. O. Box 1328, Parkersburg...,000 or if delay in reporting is likely to delay the Government in recovering such valuables, the...

  3. Safety on a Rural Community College Campus via Integrated Communications

    ERIC Educational Resources Information Center

    Gnage, Marie Foster; Dziagwa, Connie; White, Dave

    2009-01-01

    West Virginia University at Parkersburg uses a two-way emergency system as a baseline for emergency communications. The college has found that such a system, a key component of its safety and crisis management plan, can be integrated with other communication initiatives to provide focused security on the campus.

  4. 31 CFR 351.20 - What is the investment yield (interest) during the original maturity period of Series EE savings...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... email at [email protected], or by writing us at the following address: Bureau of the Public Debt... prior to 5 years from issue date at our website at www.savingsbonds.gov, by contacting us by email at [email protected], or writing to the following address: Bureau of the Public Debt, Parkersburg, West...

  5. Final Inspection of Lactated Ringer’s Resuscitation Fluid, Intravenous Sodium Chloride Solution, and Sodium Chloride-Glucose Solution Used in the Deglycerolization of Human Red Cells Frozen With 40% W/V Glycerol, Produced by the Sterimatics EDM Reflups System and Stored for 8 Months to 2.3 Years.

    DTIC Science & Technology

    1994-09-08

    SHIP LR500 000218201816 07/28/94 P N N 25 8237 SHIP LR500 000218201905 07/30/94 P N N 26 8301 SHIP LR500 000218201910 07/30/94 P N N 27 7395 SHIP...24 25 8237 SHIP LR500 000218201905 07/30/94 P 561 512 PASS 537 500 PASS 24 26 8301 SHIP LR500 000218201910 07/30/94 P 562 513 PASS 538 501 PASS 24

  6. Evaluation of Geothermal and Natural Gas Resources Beneath Camp Dawson and Opportunities for Deep Direct Use of Geothermal Energy or Natural Gas for Heat and Electricity Production; NETL-TRS-8-2017; NETL Technical Report Series; U.S. Department of Energy, National Energy Technology Laboratory: Morgantown, WV, 2017; p 148.

    SciTech Connect

    Means, Ken; Muring, Timothy M.; Sams, Neal W.

    NETL has reviewed available information and evaluated the deep geothermal and natural gas resources located beneath the Camp Dawson National Guard Training Center in West Virginia. This facility is located in the northeastern portion of the state in Preston County, near the town of Kingwood. This study reviews options for the onsite drilling of wells for the production of geothermal heat or natural gas, as well as the utilization of these resources for on-site power and heating needs. Resources of potential interest are at subsurface depths between 7,000 feet and 15,000 feet.

  7. 2. VIEW WEST, REAR AND FERNOW EXPERIMENTAL FOREST BUNKHOUSE ON ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. VIEW WEST, REAR AND FERNOW EXPERIMENTAL FOREST BUNKHOUSE ON RIGHT. (see also WV-237-6, WV-237-N-2, and historic photograph WV-237-N-5) - Parsons Nursery, Fernow Experimental Forest Well House, South side of U.S. Route 219, Parsons, Tucker County, WV

  8. PROCEEDINGS: 1991 INTERNATIONAL CONFERENCE ON MUNICIPAL WASTE COMBUSTION - VOLUME 1. SESSIONS P, 0, 1A, 2A, 3A, 4A, 6A, 6B, 9C, AND 10B

    EPA Science Inventory

    The three-volumes document 82 presentations by authors from 15 countries at the Second International Conference on Municipal Waste Combustion (MWC) in Tampa, Florida, April 16-19, 1991. The Conference fostered the exchange of current information on research concerning MWC, ash di...

  9. The Second Report on the State of the World's Animal Genetic Resources for Food and Agriculture, Part 4, The State of the Art: Box 4A4: A digital enumeration method for collecting phenotypic data for genome association

    USDA-ARS?s Scientific Manuscript database

    Consistent data across animal populations are required to inform genomic science aimed at finding important adaptive genetic variations. The ADAPTMap Digital Phenotype Collection- Prototype Method will yield a new procedure to provide consistent phenotypic data by digital enumeration of categorical ...

  10. 78 FR 45937 - Final Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-30

    ... repository Community address Mason County, West Virginia, and Incorporated Areas Docket No.: FEMA-B-1270 City..., 133 2nd Street, Hartford, WV 25247. Town of Henderson Town Hall, 1 Railroad Street, Henderson, WV...

  11. 47 CFR 97.203 - Beacon station.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Radio Astronomy Observatory, P.O. Box 2, Green Bank, WV 24944. (1) The notification must include the... Radio Astronomy Observatory at Green Bank, Pocahontas County, WV, for itself or on behalf of the Naval...

  12. View northwest, overview of building group: chicken house (HABS No. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View northwest, overview of building group: chicken house (HABS No. WV-267-D), wash house (267-C), Albert Thacker House (267-A), coal house (267-B) (left to right in photograph) - 3249 Cyrus Road (House), Cyrus, Wayne County, WV

  13. 7. Photo copy of blue print, (original in Forest Service ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Photo copy of blue print, (original in Forest Service Office, Elkins, WV), November 1933. FIRST FLOOR PLAN, SECOND FLOOR PLAN. - Parsons Nursery, Manager's Residence, South side of U.S. Route 219, Parsons, Tucker County, WV

  14. 8. Photo copy of blue print, (original in Forest Service ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Photo copy of blue print, (original in Forest Service Office, Elkins, WV), November 1933. FRONT WALL SECTION. - Parsons Nursery, Manager's Residence, South side of U.S. Route 219, Parsons, Tucker County, WV

  15. 6. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #246860), photographer unknown, ca. 1935. EQUIPMENT DETAIL, SEED WING REMOVER. - Parsons Nursery, Seed Extractor Building, South side of U.S. Route 219, Parsons, Tucker County, WV

  16. 37. Photo copy of map, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    37. Photo copy of map, (original in Forest Service Office, Elkins, WV, 'Blister Rust Survey Map), 1930. PARSONS NURSERY SITE PLAN - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  17. National Dam Inspection Program. Bear Gulch Pond Dam (NY 01089), Mohawk River Basin, Town of Summit, Schoharie County, New York. Phase I Inspection Report,

    DTIC Science & Technology

    1981-08-18

    experienced minor rockfalls . c. Appurtenant Structures 1) Intake Structure and Gate House The intake structure is reportedly a vertical 3-foot-diameter...EDWIN COVA t iRONC_ V. t>U - CF 4I: t I- AL-L. ?PFfONM’j1.L WSMT o W 5//8 wsrc-r-iwj ONLY,’ VoP e’_L4K leN ’.-/2 /S C % V41 G: (oCjf -- K /A4A’Ar Gi QF...kTM WV= SCALE S e o. AIS M 4_ --- I svWlk W/ -. JET SCU~,p, cLz’j Gi - t- ’I L j~ F I I ~O$ de.~P,~T T ~v ~tTM’,MTiQ F---- ~~flLJJ-m𔃾 IlET TL -7e IT

  18. 3. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #292222), photographer unknown, ca. 1935. VIEW EAST, CCC CAMP PARSONS, FOREST SERVICE TRUCK STORAGE ON LEFT, WATER TANK (DEMOLISHED), MESS HALL (DEMOLISHED). (see also historic photograph WV-237-20, WV-237-35) - Parsons Nursery, Civilian Conservation Corps Garage, South side of U.S. Route 219, Parsons, Tucker County, WV

  19. Actively Transmitting New DCPs - Hydrometeorological Automated Data System

    Science.gov Websites

    CT ASPETUCK RIVER NEAR ASPETUCK, C 411343 -0731926 SIGNAL ENG. HG VB 2013085 USGS01 DE2234D6 010000 CT BYRAM RIVER AT PEMBERWICK 410137 -0733940 SIGNAL ENG. HG PC VB 2013085 USGS01 17955470 010000 CT CT-CL 223 411832 -0723255 UNKNOWN HG WV WV VB HG WV WV HG EC EC EC EC EC EC 2016154 USGS01 DD3C65BA

  20. Force Protection Technologies for the 2010-2020 Timeframe

    DTIC Science & Technology

    2003-11-01

    virus V12. Monkey pox virus Viruses V13. Rift Valley fever virus V14. Tick-borne encephalitis virus (Russian Spring-Summer... virus Viruses V20. Japanese encephalitis virus R1. Coxiella burnetti R2. Bartonella Quintana (Rochlimea quintana, Rickettsia quintana) R3...fever virus WV5. Oropouche virus WV6. Powassan virus WV7. Rocio virus Viruses (Warning List) WV8. St Louis encephalitis virus WB1.

  1. Airport Activity Statistics of Certificated Route Air Carriers.

    DTIC Science & Technology

    1985-12-31

    Houlton, ME............ Presque Isle /Houlton Bluefield, WV........... Princeon/Bhzefield Huntington, WV......... Ashland/ Huntington Bonn, Germany...Benito Wheeling, WV ......... Pttaburgh/ Wheeling (Under Pennsylvania ) San Bernardino, CA ... Ontario & San Bernardino White River Junction, VT... Pennsylvania ) Spartanburg, SC........ Greenville/Spartanbury Winston-Salem, NC ... Greensboro/High Point/Winston-Salem Springfield, MA......... Hartford

  2. 78 FR 29615 - Establishment of Area Navigation (RNAV) Routes; Washington, DC

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-21

    ...). Q-72 extends between the HACKS, WV, intersection and the RAMAY, VA, WP. It provides an alternate route for jet route J-149 via a direct routing to the HACKS intersection, thus reducing miles flown for...]12'20'' W.) Q72 HACKS, WV to RAMAY, VA [New] HACKS, WV FIX (Lat. 39[deg]07'46'' N., long. 081[deg]05...

  3. 6. Photo copy of blue print, (original in Forest Service ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Photo copy of blue print, (original in Forest Service Office, Elkins, WV), George W. Root, draftsman, 1928. DETAILS FOR OFFICE/LABORATORY, SHEET 2. (see also WV-237-B-3 FOR CONSTRUCTION DETAILS) - Parsons Nursery, Nursery Office, South side of U.S. Route 219, Parsons, Tucker County, WV

  4. View northeast, overview of Albert Thacker building group: chicken house ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View northeast, overview of Albert Thacker building group: chicken house (HABS No. WV-267-D), wash house (267-C), privy (HABS No. WV-268-B), and house (267-A) (left to right in photograph) - 3249 Cyrus Road (House), Cyrus, Wayne County, WV

  5. Perspectives on Obesity and Its Treatment: Health Care Providers and the General Public in Rural West Virginia and Urban Baltimore

    ERIC Educational Resources Information Center

    Menez, Steven; Cheskin, Lawrence; Geller, Gail

    2013-01-01

    Objective: To determine and compare the perspectives of the general public and health care providers (HCPs) on obesity and its treatment in rural West Virginia (WV) and Baltimore, MD. Method: Surveys were completed in both locations by the general public (WV: "n" = 200; Baltimore: "n" = 171) and HCPs (WV: "n" = 25;…

  6. Cerulean Warbler Occurrence Atlas for Military Installations

    DTIC Science & Technology

    2010-04-01

    Army Ammuniton Plant (Closed) IN NO 2009 Army IOWA ARMY AMMUNITION PLANT IA UNCERTAIN 2009 USACE J. Percy Priest Lake TN UNCERTAIN 2009 USACE J...Stonewall Jackson Lake WV UNCERTAIN 2009 USACE Summersville Lake WV no POC Army Sunflower Army Ammunition Plant KS no POC USACE Sutton Lake WV UNCERTAIN

  7. Cerebellar cortex development in the weaver condition presents regional and age-dependent abnormalities without differences in Purkinje cells neurogenesis.

    PubMed

    Martí, Joaquín; Santa-Cruz, María C; Hervás, José P; Bayer, Shirley A; Villegas, Sandra

    2016-01-01

    Ataxias are neurological disorders associated with the degeneration of Purkinje cells (PCs). Homozygous weaver mice (wv/wv) have been proposed as a model for hereditary cerebellar ataxia because they present motor abnormalities and PC loss. To ascertain the physiopathology of the weaver condition, the development of the cerebellar cortex lobes was examined at postnatal day (P): P8, P20 and P90. Three approaches were used: 1) quantitative determination of several cerebellar features; 2) qualitative evaluation of the developmental changes occurring in the cortical lobes; and 3) autoradiographic analyses of PC generation and placement. Our results revealed a reduction in the size of the wv/wv cerebellum as a whole, confirming previous results. However, as distinguished from these reports, we observed that quantified parameters contribute differently to the abnormal growth of the wv/wv cerebellar lobes. Qualitative analysis showed anomalies in wv/wv cerebellar cytoarchitecture, depending on the age and lobe analyzed. Such abnormalities included the presence of the external granular layer after P20 and, at P90, ectopic cells located in the molecular layer following several placement patterns. Finally, we obtained autoradiographic evidence that wild-type and wv/wv PCs presented similar neurogenetic timetables, as reported. However, the innovative character of this current work lies in the fact that the neurogenetic gradients of wv/wv PCs were not modified from P8 to P90. A tendency for the accumulation of late-formed PCs in the anterior and posterior lobes was found, whereas early-generated PCs were concentrated in the central and inferior lobes. These data suggested that wv/wv PCs may migrate properly to their final destinations. The extrapolation of our results to patients affected with cerebellar ataxias suggests that all cerebellar cortex lobes are affected with several age-dependent alterations in cytoarchitectonics. We also propose that PC loss may be regionally

  8. Neural Network Autopilot System for a Mathematical Model of the Boeing 747

    DTIC Science & Technology

    1998-08-04

    the NASA/Aurora Theseus ", Thesis WVU MAE Dept., Morgantown, WV, June 1996. [9] Napolitano, M.R., Neppach, C, Casdorph, V., Naylor, S. "On-Line...Validation Schemes for Implementation on the NASA/Aurora Theseus ", Thesis WVU MAE Dept., Morgantown, WV, June 1996. [9] Napolitano, M.R., Neppach, C...Schemes for Implementation on the NASA/Aurora Theseus ", Thesis WVU MAE Dept., Morgantown, WV, June 1996. [9] Napolitano, M.R., Neppach, C, Casdorph, V

  9. 30 CFR 23.3 - Application procedures and requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... and Health Administration, Approval and Certification Center, 765 Technology Drive, Triadelphia, WV... that are critical to the safety of the product; and (4) All documentation, including drawings and...

  10. 30 CFR 23.3 - Application procedures and requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... and Health Administration, Approval and Certification Center, 765 Technology Drive, Triadelphia, WV... that are critical to the safety of the product; and (4) All documentation, including drawings and...

  11. 30 CFR 23.3 - Application procedures and requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... and Health Administration, Approval and Certification Center, 765 Technology Drive, Triadelphia, WV... that are critical to the safety of the product; and (4) All documentation, including drawings and...

  12. 30 CFR 23.3 - Application procedures and requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... and Health Administration, Approval and Certification Center, 765 Technology Drive, Triadelphia, WV... that are critical to the safety of the product; and (4) All documentation, including drawings and...

  13. 30 CFR 23.3 - Application procedures and requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... and Health Administration, Approval and Certification Center, 765 Technology Drive, Triadelphia, WV... that are critical to the safety of the product; and (4) All documentation, including drawings and...

  14. 5. VIEW FROM SLIGHTLY FARTHER DOWN SERVICE ROAD, LOOKING SOUTHEAST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. VIEW FROM SLIGHTLY FARTHER DOWN SERVICE ROAD, LOOKING SOUTHEAST AT ELECTRICITY SUPPLY BUILDING, LABORATORY, AND OFFICE. - Standard Lime & Stone Quarry, County Route 27, Millville, Jefferson County, WV

  15. 30 CFR 18.81 - Field modification of approved (permissible) equipment; application for approval of modification...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MOTOR-DRIVEN MINE EQUIPMENT AND ACCESSORIES... and Certification Center, 765 Technology Drive, Triadelphia, WV 26059. (b) Proposed modifications...

  16. 7. William E. Barrett, Photographer, August 1975. LOG PONDS LOOKING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. William E. Barrett, Photographer, August 1975. LOG PONDS LOOKING WEST FROM POWERHOUSE ROOF. TRANSFORMER SHED IN FOREGROUND. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  17. 78 FR 10562 - Proposed Establishment of Area Navigation (RNAV) Routes; Washington, DC

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-14

    ... (VORTAC) aid and the OTTTO, VA, waypoint (WP). Q-72 would extend between the HACKS, WV, intersection and... HACKS intersection, thus reducing miles flown for RNAV-equipped aircraft. Q-80 would extend between the...., long. 078[deg]22'27'' W.) OTTTO, VA WP (Lat. 38[deg]51'16'' N., long. 078[deg]12'20'' W.) Q72 HACKS, WV...

  18. 4. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #302582, 'Insect/disease control'), D. A. Oliver, May 1935. VIEW NORTHEAST. - Parsons Nursery, Packing Building, South side of U.S. Route 219, Parsons, Tucker County, WV

  19. 75 FR 3224 - Dominion Transmission, Inc.; Notice of Public Scoping Meetings for the Appalachian Gateway Project

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-20

    ... Riverside Drive, West Newton, PA. Thursday, January 21, 2010 at 6 p.m.(EST), Waynesburg Central High School... School-- Auditorium, One Lumberjack Lane, Pine Grove, WV. Thursday, January 28, 2010 at 6 PM (EST), Riverside High School-- Auditorium, 1 Warrier Way, Belle, WV. This notice is being sent to the Commission's...

  20. 25. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    25. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #248333, 'Tree nurseries-seed bed preparation'), D. A. Oliver, 1930. VIEW SOUTHEAST, STORAGE SHED (DEMOLISHED), POPLAR SEEDLINGS, SHADED SEEDLING BEDS ON RIGHT. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  1. 14. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #333469, 'Tree nurseries-seed bed preparation'), D. A. Oliver, November 1936. VIEW NORTHEAST, ORIGINAL WASH HOUSE, GARAGE (DEMOLISHED), WORKSHOP/WAREHOUSE, AND NURSERY OFFICE. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  2. 27. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    27. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #292219, 'Tree nurseries-transplanting-transplanting beds'), D. A. Oliver, 1934. VIEW SOUTHWEST, TRANSPLANT SHED AND MAN WITH TRANSPLANT BOARD. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  3. 16. Photocopy of photograph, (original in Forest Service Office, Elkins, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. Photocopy of photograph, (original in Forest Service Office, Elkins, WV, photo #302581, 'Tree nurseries-Broad view, C. C. Corps project'), D. A. Oliver, May 1935. AERIAL VIEW SOUTH. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  4. 75 FR 71462 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-23

    .../10 Specialist (Workers). 74805 Cranberry Resources, LLC Beckley, WV........ 11/01/10 10/25/10 (Company). 74806 Cranberry Hardwoods, Beckley, WV........ 11/01/10 10/25/10 Inc. (Company). 74807 UView... Mountain City Lumber Mountain City, TN.. 11/05/10 10/25/10 Company (Company). 74826 Cranberry Lumber...

  5. View southeast, overview of building group: coal house (HABS No. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View southeast, overview of building group: coal house (HABS No. WV-267-B), large tree, Albert Thacker House (267-A), wash house (267-C), Eustace Chadwick House (268-A) (on lot to south), chicken house (267-D), and small tree (left to right in photograph) - 3249 Cyrus Road (House), Cyrus, Wayne County, WV

  6. CSX rail trestle conversion to ATV trail.

    DOT National Transportation Integrated Search

    2014-10-01

    The Hatfield and McCoy Trail Authority (HMRRA) operates the Rockhouse ATV trail : between Man and Gilbert WV. Prior to this project, trail riders wishing to cross the Guyandotte : River had to ride the streets of Man, WV. The project goal was to prom...

  7. 77 FR 68737 - Procurement List, Proposed Deletions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-16

    ...: Janitorial/Custodial, Defense Logistics Agency: Point Pleasant Depot, Defense National Stockpile Zone, 2601 Madison Avenue, Point Pleasant, WV. NPA: Prestera Center for Mental Health Services, Inc., Huntington, WV. Contracting Activity: Defense Logistics Agency Support Services-- DSS, Fort Belvoir, VA. Service Type/Location...

  8. 12. Photocopy of photograph, (original in Forest Service Office, Elkins, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Photocopy of photograph, (original in Forest Service Office, Elkins, WV, photo #305568, 'show me tour'), photographer and date unknown. VIEW SOUTHWEST, NURSERY MANAGER'S RESIDENCE, NURSERY OFFICE, WORKSHOP/WAREHOUSE, ORIGINAL WASH HOUSE. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  9. 5. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #298167, 'Nursery Manager's residence and garage,'), D. A. Oliver, November 1934. VIEW NORTHEAST. - Parsons Nursery, Manager's Residence, South side of U.S. Route 219, Parsons, Tucker County, WV

  10. 26. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. Photo copy of photograph, (original in Forest Service Office, Elkins, WV), photographer unknown, ca. 1936. VIEW NORTHWEST, GARAGE (DEMOLISHED), NURSERY MANAGER'S GARAGE AND RESIDENCE, AND PACKING BUILDING, TRANSPLANT SHEDS AND PLOW IN FOREGROUND. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  11. 13. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #333464, 'Tree nurseries-seed bed preparation'), D. A. Oliver, November 1936. VIEW SOUTHEAST, WORKSHOP/WAREHOUSE, ORIGINAL WASH HOUSE, NURSERY OFFICE, NURSERY MANAGER'S RESIDENCE, GARAGE (DEMOLISHED), PUMP HOUSE, AND FERNOW EXPERIMENTAL FOREST RESIDENCE. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  12. 39. Photo copy of site plan, (original in Forest Service ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    39. Photo copy of site plan, (original in Forest Service Office, Elkins, WV, 'Parsons Nursery Special Use Permit, West Virginia Department of Natural Resources'), 1969. PARSONS NURSERY SITE PLAN. CORROLATES TO PARSONS NURSERY AT TIME OF FLOOD, NOVEMBER, 1985. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  13. 75 FR 20597 - Radio Broadcasting Services; AM or FM Proposals To Change the Community of License

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-20

    ... FEDERAL COMMUNICATIONS COMMISSION Radio Broadcasting Services; AM or FM Proposals To Change the... applicants filed AM or FM proposals to change the community of license: COCHISE BROADCASTING LLC, Station... WETZ-FM, Facility ID 18534, BPH- 20100329AFI, From NEW MARTINSVILLE, WV, To VIENNA, WV; LOUT, JAMES M...

  14. 4. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #298180, 'seed extracting equipment'), D. A. Oliver, 1934. LOWER FLOOR, LOOKING WEST, SEED EXTRACTOR. - Parsons Nursery, Seed Extractor Building, South side of U.S. Route 219, Parsons, Tucker County, WV

  15. 22. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #244025, 'seed planter'), D. A. Oliver, 1930. VIEW EAST, FRONT OF WORKSHOP/WAREHOUSE, SEED BED PLANTER. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  16. 23. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    23. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #248336, 'Tree nurseries-seed bed seeding machine'), D. A. Oliver, 1930. VIEW WEST, SEEDING MACHINE. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  17. 5. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #298181), D. A. Oliver, 1934. LOWER FLOOR, LOOKING WEST, SEED EXTRACTOR. - Parsons Nursery, Seed Extractor Building, South side of U.S. Route 219, Parsons, Tucker County, WV

  18. Case Study: Effect of Handrim Diameter on Performance in a Paralympic Wheelchair Athlete

    ERIC Educational Resources Information Center

    Costa, Gabriel Brizuela; Rubio, Miguel Polo; Belloch, Salvador Llana; Soriano, Pedro Perez

    2009-01-01

    This study, with a top T-52 class athlete, determines the relationship between stroke frequency (SF) and push time (PT) and wheelchair velocity (Wv) using different handrim diameters (HD) and the effect of different HDs on the athlete's heart rate (HR) and blood lactate (LACT) at competition speeds. Wv shows a linear-direct relationship with SF…

  19. TASTE DISCRIMINATION LEARNING IN PREWEANLING RATS

    EPA Science Inventory

    Seventeen-day-old rat pups received intraoral infusions of two novel flavors, coffee (.625% w/v Sanka, decaffeinated) and saccharin (.5% w/v), of which one (CS+) was paired with a .75X body weight, i.p. injection of 0.4 M LiCl, and the other (CS-) was presented alone. n the follo...

  20. 18. Photocopy of original postcard, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. Photocopy of original postcard, (original in Forest Service Office, Elkins, WV, 'U. S. Forest Nursery with CCC Camp in Background-Parsons, W. Va.'), photographer unknown, ca. 1936. AERIAL VIEW EAST, ORIGINAL WASH HOUSE, WORKSHOP/WAREHOUSE, TWO EQUIPMENT BUILDINGS (DEMOLISHED) IN FOREGROUND, CCC CAMP PARSONS IN BACKGROUND. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  1. The Vestibulo-Ocular Reflex in Man during Voluntary Head Oscillation under Three Visual Conditions.

    DTIC Science & Technology

    1980-07-15

    040’- ’ -O 1>, GA 0v WV D Q)G w O V -.-c S -a 𔃾- COd w- Co -w 00 0- > 0000’)-4A-1 j >.M40.M44003.0V - 0 >I4~ .-4-4.AfV Q) - x > I w൰ O QA 101 00...44 : .o w-’ w l mmQzmI , - - v >’ N40 5. a .wx > s , ,w n4 I a wC u C wC CC c a4 0 >E a0 w > 0’ 0x n, r’ w’ I I~ o** 4)-7 r_ C -𔃾 4- C 4 4 -4𔃺 c...8217. 0 a.4A 010 0 GA A-C 00 C :j m >0 0 --0 30. . m0 No-0 m-0.. 0) A-A- . A-.4𔃺m0 0 m-A >7 -O 1N 0C0 0 004w4w0 m0 >O v 0 0 n 4 w .w 0V A0w 0m GAO -0

  2. 320-Row wide volume CT significantly reduces density heterogeneity observed in the descending aorta: comparisons with 64-row helical CT.

    PubMed

    Yamashiro, Tsuneo; Miyara, Tetsuhiro; Honda, Osamu; Kamiya, Ayano; Tanaka, Yuko; Murayama, Sadayuki

    2014-01-01

    The aim of this study was to compare density heterogeneity on wide volume (WV) scans with that on helical CT scans. 22 subjects underwent chest CT using 320-WV and 64-helical modes. Density heterogeneity of the descending aorta was evaluated quantitatively and qualitatively. At qualitative assessment, the heterogeneity was judged to be smaller on WV scans than on helical scans (p<0.0001). Mean changes in aortic density between two contiguous slices were 1.64 HU (3.40%) on WV scans and 2.29 HU (5.19%) on helical scans (p<0.0001). CT density of thoracic organs is more homogeneous and reliable on WV scans than on helical scans. Copyright © 2013 Elsevier Ltd. All rights reserved.

  3. Optimization of γ-amino butyric acid production in a newly isolated Lactobacillus brevis.

    PubMed

    Binh, Tran Thi Thanh; Ju, Wan-Taek; Jung, Woo-Jin; Park, Ro-Dong

    2014-01-01

    An isolate from kimchi, identified as Lactobacillus brevis, accumulated γ-aminobutyric acid (GABA), a major inhibitory neurotransmitter, in the culture medium. Optimal culture conditions for growth of L. brevis and production of GABA were 6 % (w/v) l-glutamic acid, 4 % (w/v) maltose, 2 % (w/v) yeast extract, 1 % (w/v) NaCl, 1 % (w/v) CaCl2, 2 g Tween 80/l, and 0.02 mM pyridoxal 5′-phosphate at initial pH 5.25 and 37 °C. GABA reached 44.4 g/l after 72 h cultivation with a conversion rate 99.7 %, based on the amount (6 %) of l-glutamic acid added. GABA was purified using ion exchange column chromatography with 70 % recovery and 97 % purity.

  4. The effect of bioleaching on sewage sludge pyrolysis.

    PubMed

    Chen, Zhihua; Hu, Mian; Cui, Baihui; Liu, Shiming; Guo, Dabin; Xiao, Bo

    2016-02-01

    The effects of bioleaching on sewage sludge pyrolysis were studied. Sewage sludge was treated by bioleaching with solid concentrations of 6% (w/v), 8% (w/v), 10% (w/v). Results showed that bioleaching treatment could modify the physicochemical properties of sewage sludge and enhance the metals removal. The optimum removal efficiencies of heavy metals were achieved with solid concentration of 6% (w/v) bioleaching treatment: Cu, 73.08%; Zn, 78.67%; Pb, 24.65%; Cd, 79.46%. The characterization results of thermogravimetric analysis (TGA) showed that the bioleached sewage sludge with a 6% (w/v) solid concentration treatment was the easiest to decompose. Pyrolytic experiments of bioleached sewage sludge were performed in a laboratory-scale fixed bed reactor. Results indicated that bioleaching treatment greatly influenced the product yields and gas composition. Copyright © 2015 Elsevier Ltd. All rights reserved.

  5. Identification of a novel multiple kinase inhibitor with potent antiviral activity against influenza virus by reducing viral polymerase activity

    SciTech Connect

    Sasaki, Yutaka; Kakisaka, Michinori; Chutiwitoonchai, Nopporn

    Highlights: • Screening of 50,000 compounds and subsequent lead optimization identified WV970. • WV970 has antiviral effects against influenza A, B and highly pathogenic viral strains. • WV970 inhibits viral genome replication and transcription. • A target database search suggests that WV970 may bind to a number of kinases. • KINOMEscan screening revealed that WV970 has inhibitory effects on 15 kinases. - Abstract: Neuraminidase inhibitors are the only currently available influenza treatment, although resistant viruses to these drugs have already been reported. Thus, new antiviral drugs with novel mechanisms of action are urgently required. In this study, we identified amore » novel antiviral compound, WV970, through cell-based screening of a 50,000 compound library and subsequent lead optimization. This compound exhibited potent antiviral activity with nanomolar IC{sub 50} values against both influenza A and B viruses but not non-influenza RNA viruses. Time-of-addition and indirect immunofluorescence assays indicated that WV970 acted at an early stage of the influenza life cycle, but likely after nuclear entry of viral ribonucleoprotein (vRNP). Further analyses of viral RNA expression and viral polymerase activity indicated that WV970 inhibited vRNP-mediated viral genome replication and transcription. Finally, structure-based virtual screening and comprehensive human kinome screening were used to demonstrate that WV970 acts as a multiple kinase inhibitor, many of which are associated with influenza virus replication. Collectively, these results strongly suggest that WV970 is a promising anti-influenza drug candidate and that several kinases associated with viral replication are promising drug targets.« less

  6. A systematic evaluation of solubility enhancing excipients to enable the generation of permeability data for poorly soluble compounds in Caco-2 model.

    PubMed

    Shah, Devang; Paruchury, Sundeep; Matta, Muralikrishna; Chowan, Gajendra; Subramanian, Murali; Saxena, Ajay; Soars, Matthew G; Herbst, John; Haskell, Roy; Marathe, Punit; Mandlekar, Sandhya

    2014-01-01

    The study presented here identified and utilized a panel of solubility enhancing excipients to enable the generation of flux data in the Human colon carcinoma (Caco-2) system for compounds with poor solubility. Solubility enhancing excipients Dimethyl acetamide (DMA) 1 % v/v, polyethylene glycol (PEG) 400 1% v/v, povidone 1% w/v, poloxamer 188 2.5% w/v and bovine serum albumin (BSA) 4% w/v did not compromise Caco-2 monolayer integrity as assessed by trans-epithelial resistance measurement (TEER) and Lucifer yellow (LY) permeation. Further, these excipients did not affect P-glycoprotein (P-gp) mediated bidirectional transport of digoxin, permeabilities of high (propranolol) or low permeability (atenolol) compounds, and were found to be inert to Breast cancer resistant protein (BCRP) mediated transport of cladribine. This approach was validated further using poorly soluble tool compounds, atazanavir (poloxamer 188 2.5% w/v) and cyclosporine A (BSA 4% w/v) and also applied to new chemical entity (NCE) BMS-A in BSA 4% w/v, for which Caco-2 data could not be generated using the traditional methodology due to poor solubility (<1 µM) in conventional Hanks balanced salt solution (HBSS). Poloxamer 188 2.5% w/v increased solubility of atazanavir by >8 fold whereas BSA 4% w/v increased the solubility of cyclosporine A and BMS-A by >2-4 fold thereby enabling permeability as well as efflux liability estimation in the Caco-2 model with reasonable recovery values. To conclude, addition of excipients such as poloxamer 188 2.5% w/v and BSA 4% w/v to HBSS leads to a significant improvement in the solubility of the poorly soluble compounds resulting in enhanced recoveries without modulating transporter-mediated efflux, expanding the applicability of Caco-2 assays to poorly soluble compounds.

  7. PATCH - STS-33/51-L (TEACHER IN SPACE)

    NASA Image and Video Library

    1985-08-02

    S85-38312 (September 1985) --- Logo designed for use by the 10 finalists in NASA’s Teacher in Space Project, who were at JSC for training and orientation the week of July 8–12, 1985. They are David M. Marquart, Boise High, Boise, Idaho; Michael W. Metcalf, Hazen Union School, Hardwick, Vermont; Judith Marie Garcia, Thomas Jefferson School for Science and Technology, Alexandria, Virginia; Peggy J. Lathlaen, Westwood Elementary, Friendswood, Texas; Niki Mason Wenger, Vandevender Junior High, Parkersburg, West Virginia; Barbara R. Morgan, McCall-Donnelly Elementary, McCall, Idaho; Kathleen Anne Beres, Kenwood High, Baltimore, Maryland; Richard A. Methia, New Bedford High, New Bedford, Mass.; Sharon Christa McAuliffe, Concord High, Concord, New Hampshire; and Robert S. Foerster, Cumberland Elementary School, West Lafayette, Indiana. Photo credit: NASA

  8. Perspectives on obesity and its treatment: health care providers and the general public in rural West Virginia and urban Baltimore.

    PubMed

    Menez, Steven; Cheskin, Lawrence; Geller, Gail

    2013-12-01

    To determine and compare the perspectives of the general public and health care providers (HCPs) on obesity and its treatment in rural West Virginia (WV) and Baltimore, MD. Surveys were completed in both locations by the general public (WV: n = 200; Baltimore: n = 171) and HCPs (WV: n = 25; Baltimore: n = 15). BMI (body mass index) ≥ 30 (WV: n = 94; Baltimore: n = 58) was associated with a stronger belief in the heritability of obesity and with the ability to control obesity by controlling food cost, compared with those with normal BMI (WV: n = 42; Baltimore: n = 57). Those with a high school education (WV: n = 112; Baltimore: n = 113) were less likely to agree that obesity is a problem in the community and that proper diet and exercise are realistic expectations, compared with those with at least some higher education. Perspectives of HCPs differed significantly from the general public in both locations. Many differences in perspective on obesity exist between WV and Baltimore, within both populations, and between HCPs and the general public in both settings. A better understanding of patient views is important for effective obesity management. HCPs must consider each patient's level of understanding when discussing management and consequences of obesity. More time spent with patients who have less insight into their obesity may improve patient adherence with treatment and overall patient outcomes.

  9. The effect of increasing chitosan on the characteristics of bioplastic from starch talas (Colocasia esculenta) using plasticizer sorbitol

    NASA Astrophysics Data System (ADS)

    Ginting, M. H. S.; Lubis, M.; Sidabutar, T.; Sirait, T. P.

    2018-03-01

    The aims of this research to determine the profile of starch gelatinization, bioplastic and the effect of increasing chitosan and sorbitol to the properties of tensile strength and elongation of break bioplastic. Preparation of bioplastics was used by casting method, that is 30% w/v solution of starch mixed with chitosan solution (0.5 w/v; 1 w/v; 1.5 w/v; 2 w/v; and 2.5 w/v) and plasticizer sorbitol (10 % w/w; 20 % w/w; 30 % w/w; 40 % w/w and 50 % w/w) were heated using a hotplate magnetic stirrer at 750C. The results of Rapid Visco Analyzer (RVA) obtained by starch and bioplastic gelatinization temperature of 72.94°C 77.72°C with peak viscosity 6632 cP and 3476 cP. Analysis of Fourier Transform Infrared (FTIR) and Scanning Electron Microscopy (SEM) obtained the change a functional group of bioplastic OH at wave number 3765 cm-1 and uneven chitosan distribution, and there is still an empty fraction. The addition of chitosan and sorbitol had an effect on tensile strength and elongation at break, tensile strength and elongation at break the highest of 8.36 MPa and 22.06% in starch composition 30%, 2.5 w/v chitosan and sorbitol 30% w/w.

  10. Transdermal permeation of trimetazidine from nerodilol-based HPMC gel drug reservoir system across rat epidermis.

    PubMed

    Krishnaiah, Yellela S; Al-Saidan, Saleh M

    2008-01-01

    To study the in vitro transdermal permeation of trimetazidine from hydroxypropylmethyl cellulose (HPMC) gel drug reservoir system using nerodilol as a penetration enhancer. An HPMC gel containing selected concentrations of nerodilol (0, 2, 4 or 5% w/v) and 2.5% w/v of trimetazidine was prepared, and subjected to in vitro permeation studies across rat epidermis. The amount of trimetazidine permeated at different time intervals (1, 2, 4, 8, 12, 18 and 24 h) was estimated, and the data were analyzed to calculate various permeation parameters. There was an increase in the amount of trimetazidine (8,719.7 +/- 153.3 microg/cm(2))permeated across the rat epidermis up to 24 h (Q(24)) with an increase in nerodilol concentration (5% w/v) in HPMC gel drug reservoir. However, no significant difference (p > 0.05) was observed in the amount of drug permeated (Q(24)) with 5% w/v of nerodilol when compared to that obtained with 4% w/v of nerodilol (8,484.5 +/- 165.8 microg/cm(2)). Nerodilol, at a concentration of 4% w/v enhanced the flux of trimetazidine across rat epidermis by about 1.96 times when compared to control. The HPMC gel drug reservoir containing 4% w/v of nerodilol showed optimal transdermal permeation of trimetazidine. (c) 2007 S. Karger AG, Basel.

  11. Multivesicular liposomal bupivacaine at the sciatic nerve

    PubMed Central

    McAlvin, J. Brian; Padera, Robert F.; Shankarappa, Sahadev A.; Reznor, Gally; Kwon, Albert H.; Chiang, Homer; Yang, Jason; Kohane, Daniel S.

    2014-01-01

    Clinical translation of sustained release formulations for local anesthetics has been limited by adverse tissue reaction. Exparel™ (DepoFoam bupivacaine) is a new liposomal local anesthetic formulation whose biocompatibility near nerve tissue is not well characterized. Exparel™ injection caused sciatic nerve blockade in rats lasting 240 minutes compared to 120 minutes for 0.5% (w/v) bupivacaine HCl and 210 minutes for 1.31% (w/v) bupivacaine HCl (same bupivacaine content as Exparel™). On histologic sections four days after injection, median inflammation scores in the Exparel™ group (2.5 of 4) were slightly higher than in groups treated with bupivacaine solutions (score 2). Myotoxicity scores in the Exparel™ group (2.5 of 6) were similar to in the 0.5% (w/v) bupivacaine HCl group (3), but significantly less than in the 1.31% (w/v) bupivacaine HCl group (5). After two weeks, inflammation from Exparel™ (score 2 of 6) was greater than from 0.5% (w/v) bupivacaine HCl (1) and similar to that from 1.31% (w/v) bupivacaine HCl (1). Myotoxicity in all three groups was not statistically significantly different. No neurotoxicity was detected in any group. Tissue reaction to Exparel™ was similar to that of 0.5% (w/v) bupivacaine HCl. Surveillance for local tissue injury will be important during future clinical evaluation. PMID:24612918

  12. An Assessment of Worldview-2 Imagery for the Classification Of a Mixed Deciduous Forest

    NASA Astrophysics Data System (ADS)

    Carter, Nahid

    Remote sensing provides a variety of methods for classifying forest communities and can be a valuable tool for the impact assessment of invasive species. The emerald ash borer (Agrilus planipennis) infestation of ash trees (Fraxinus) in the United States has resulted in the mortality of large stands of ash throughout the Northeast. This study assessed the suitability of multi-temporal Worldview-2 multispectral satellite imagery for classifying a mixed deciduous forest in Upstate New York. Training sites were collected using a Global Positioning System (GPS) receiver, with each training site consisting of a single tree of a corresponding class. Six classes were collected; Ash, Maple, Oak, Beech, Evergreen, and Other. Three different classifications were investigated on four data sets. A six class classification (6C), a two class classification consisting of ash and all other classes combined (2C), and a merging of the ash and maple classes for a five class classification (5C). The four data sets included Worldview-2 multispectral data collection from June 2010 (J-WV2) and September 2010 (S-WV2), a layer stacked data set using J-WV2 and S-WV2 (LS-WV2), and a reduced data set (RD-WV2). RD-WV2 was created using a statistical analysis of the processed and unprocessed imagery. Statistical analysis was used to reduce the dimensionality of the data and identify key bands to create a fourth data set (RD-WV2). Overall accuracy varied considerably depending upon the classification type, but results indicated that ash was confused with maple in a majority of the classifications. Ash was most accurately identified using the 2C classification and RD-WV2 data set (81.48%). A combination of the ash and maple classes yielded an accuracy of 89.41%. Future work should focus on separating the ash and maple classifiers by using data sources such as hyperspectral imagery, LiDAR, or extensive forest surveys.

  13. White spotting variant mouse as an experimental model for ovarian aging and menopausal biology.

    PubMed

    Smith, Elizabeth R; Yeasky, Toni; Wei, Jain Qin; Miki, Roberto A; Cai, Kathy Q; Smedberg, Jennifer L; Yang, Wan-Lin; Xu, Xiang-Xi

    2012-05-01

    Menopause is a unique phenomenon in modern women, as most mammalian species possess a reproductive period comparable with their life span. Menopause is caused by the depletion of germ cell-containing ovarian follicles and in laboratory studies is usually modeled in animals in which the ovarian function is removed through ovariectomy or chemical poisoning of the germ cells. Our objective was to explore and characterize the white spotting variant (Wv) mice that have reduced ovarian germ cell abundance, a result of a point mutation in the c-kit gene that decreases kinase activity, as a genetic model for use in menopause studies. Physiological and morphological features associated with menopause were determined in female Wv/Wv mice compared with age-matched wildtype controls. Immunohistochemistry was used to evaluate the presence and number of follicles in paraffin-embedded ovaries. Bone density and body composition were evaluated using the PIXImus x-ray densitometer, and lipids, calcium, and hormone levels were determined in serum using antigen-specific enzyme immunoassays. Heart and body weight were measured, and cardiac function was evaluated using transthoracic echocardiography. The ovaries of the Wv/Wv females have a greatly reduced number of normal germ cells at birth compared with wildtype mice. The remaining follicles are depleted by around 2 months, and the ovaries develop benign epithelial lesions that resemble morphological changes that occur during ovarian aging, whereas a normal mouse ovary has numerous follicles at all stages of development and retains some follicles even in advanced age. Wv mice have elevated plasma gonadotropins and reduced estrogen and progesterone levels, a significant reduction in bone mass density, and elevated serum cholesterol and lipoprotein levels. Moreover, the Wv female mice have enlarged hearts and reduced cardiac function. The reduction of c-kit activity in Wv mice leads to a substantially diminished follicular endowment in

  14. 6. VIEW OF POWER PLANT BUILDING LOOKING NORTHWEST. DRY CANAL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. VIEW OF POWER PLANT BUILDING LOOKING NORTHWEST. DRY CANAL BED TO THE LEFT. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  15. 9. EXTERIOR PERSPECTIVE OF POWER PLANT BUILDING LOOKING NORTHEAST. DRY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. EXTERIOR PERSPECTIVE OF POWER PLANT BUILDING LOOKING NORTHEAST. DRY CANAL BED IN FOREGROUND. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  16. 1. VIEW OF POWER PLANT LOOKING SOUTHEAST. SEVEN TURBINE FLUMES ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. VIEW OF POWER PLANT LOOKING SOUTHEAST. SEVEN TURBINE FLUMES VISIBLE IN FRONT OF BUILDING. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  17. 26. DETAIL VIEW OF THE ADJUSTABLE FIELD RESISTTOR MANUAL CONTROLS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. DETAIL VIEW OF THE ADJUSTABLE FIELD RESISTTOR MANUAL CONTROLS AND SWITCH BOXES. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  18. 10. WEST WALL OF POWER PLANT BUILDING LOOKING EAST SOUTHEAST. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. WEST WALL OF POWER PLANT BUILDING LOOKING EAST SOUTHEAST. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  19. 63. Photocopy of photograph, no date. MAP OF POTOMAC EDISON ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    63. Photocopy of photograph, no date. MAP OF POTOMAC EDISON COMPANY SYSTEM. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  20. 4. NORTH ELEVATION OF POWER PLANT LOOKING SOUTH SOUTHWEST. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. NORTH ELEVATION OF POWER PLANT LOOKING SOUTH SOUTHWEST. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  1. 13. VIEW FROM POTOMAC RIVER BRIDGE PLATFORM WEST TOWARDS STATION. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. VIEW FROM POTOMAC RIVER BRIDGE PLATFORM WEST TOWARDS STATION. HARPERS FERRY DEPOT IS ON LEFT, NORTH TRACK WAITING STATION IS ON RIGHT. - Baltimore & Ohio Railroad, Harpers Ferry Station, Potomac Street, Harpers Ferry, Jefferson County, WV

  2. 18. TURBINE AND GENERATOR SHAFT IN CONCRETE HOUSING OF THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. TURBINE AND GENERATOR SHAFT IN CONCRETE HOUSING OF THE TURBINE FLUME. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  3. 3. VIEW OF POWER PLANT LOOKING SOUTH INTO THE REMAINS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. VIEW OF POWER PLANT LOOKING SOUTH INTO THE REMAINS OF THE TURBINE FLUMES. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  4. 11. EAST WALL OF POWER PLANT BUILDING LOOKING WEST. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. EAST WALL OF POWER PLANT BUILDING LOOKING WEST. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  5. 14. INTERIOR OF POWER PLANT LOOKING SOUTHEAST AT ELECTRICAL PANEL. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. INTERIOR OF POWER PLANT LOOKING SOUTHEAST AT ELECTRICAL PANEL. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  6. 12. CANAL SLUICE GATE LOCATED 150' WEST OF POWER PLANT. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. CANAL SLUICE GATE LOCATED 150' WEST OF POWER PLANT. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  7. 8. VIEW OF WESTERN END OF THE POWER PLANT BUILDING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. VIEW OF WESTERN END OF THE POWER PLANT BUILDING LOOKING NORTH. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  8. 2. VIEW OF POWER PLANT LOOKING SOUTHEAST. Potomac Power ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. VIEW OF POWER PLANT LOOKING SOUTHEAST. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  9. 17. TOP OF TURBINE LOOKING NORTHWEST. SHAFT TO GENERATOR IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. TOP OF TURBINE LOOKING NORTHWEST. SHAFT TO GENERATOR IN CENTER. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  10. 7. EXTERIOR OF POWER PLANT BUILDING LOOKING NORTHWEST. DETAIL OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. EXTERIOR OF POWER PLANT BUILDING LOOKING NORTHWEST. DETAIL OF TRASH RACK IN FOREGROUND. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  11. Detail exterior view looking north showing piping system adjacent to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail exterior view looking north showing piping system adjacent to engine house. Gas cooling system is on far right. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  12. 47. INTERIOR VIEW, DETAIL OF CONVEYOR BELT SYSTEM SYSTEM WITH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    47. INTERIOR VIEW, DETAIL OF CONVEYOR BELT SYSTEM SYSTEM WITH BACK BELT DROPPING HARDENED NAILS ON THE FRONT BELT TO BE TEMPERED; MOTION STOPPED - LaBelle Iron Works, Thirtieth & Wood Streets, Wheeling, Ohio County, WV

  13. 12. CONSTRUCTION OF FOREBAY; SLUICEGATE IN CENTER AND ORIGINAL STONE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. CONSTRUCTION OF FOREBAY; SLUICEGATE IN CENTER AND ORIGINAL STONE DAM ABUTMENT ENCASED IN CONCRETE ON RIGHT, March 14, 1918. - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  14. 11. DETAIL OF EXTREMELY DETERIORATED CONDITION OF ORIGINAL STONE DAM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. DETAIL OF EXTREMELY DETERIORATED CONDITION OF ORIGINAL STONE DAM ABUTMENT AND REASON FOR ENCASING ABUTMENT IN CONCRETE, c. 1918. - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  15. 76 FR 66756 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-27

    ... received a certification of eligibility to apply for trade adjustment assistance benefits and such supply...; Coastal Lumber Company, Hacker Valley, WV: September 7, 2010 TA-W-80,422F; Coastal Lumber Company...

  16. 76 FR 66328 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-26

    ... received a certification of eligibility to apply for trade adjustment assistance benefits and such supply...-80,422E; Coastal Lumber Company, Hacker Valley, WV: September 7, 2010 TA-W-80,422F; Coastal Lumber...

  17. 77 FR 10606 - Qualification of Drivers; Exemption Applications; Vision

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-22

    ... comments on-line. Privacy Act: Anyone may search the electronic form of all comments received into any of... (TX), Dale M. Cannon (OR), Jamie French (NC), Wayne H. Holt (UT), Billy R. Jefferies (WV), Carlos A...

  18. West Virginia Peer Exchange : Streamlining Highway Safety Improvement Program Project Delivery - An RSPCB Peer Exchange

    DOT National Transportation Integrated Search

    2014-09-01

    The West Virginia Division of Highways (WV DOH) hosted a Peer Exchange to share information and experiences for streamlining Highway Safety Improvement Program (HSIP) project delivery. The event was held September 23 to 24, 2014 in Charleston, West V...

  19. West Virginia peer exchange : streamlining highway safety improvement program project delivery.

    DOT National Transportation Integrated Search

    2015-01-01

    The West Virginia Division of Highways (WV DOH) hosted a Peer Exchange to share information and experiences : for streamlining Highway Safety Improvement Program (HSIP) project delivery. The event was held September : 22 to 23, 2014 in Charleston, We...

  20. East yard, looking southwest at car repairer's locker house (left), ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    East yard, looking southwest at car repairer's locker house (left), switchment shanty (center), and material storage rack (right). - Chesapeake & Ohio Railroad, Thurmond Yards, East side New River, mouths of Arbuckle & Dunlop Circles, Thurmond, Fayette County, WV

  1. 32. William E. Barrett, Photographer, 1973. DEADEND WELL WITH WOODEN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    32. William E. Barrett, Photographer, 1973. DEAD-END WELL WITH WOODEN OIL TANK, PIPE ROCKER ARM. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  2. FAA Air Traffic Activity: Fiscal Year 1988

    DTIC Science & Technology

    1988-01-01

    12390 5335 TOTAL OPERATIONS ......................................................................... 146585 31593 9014 97579 8399 TEXARKANA (TXK) N...14402 12385 2017 TOTAL OPERATIONS ....................................................................... 56240 403 9574 41417 4846...WV N 390 39876 TEXARKANA ........................................................ AR N 351 56414 SOUTH LAKE TAHOE

  3. 1. Historic American Buildings Survey Ian McLaughlin Photographer October 27, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Historic American Buildings Survey Ian McLaughlin Photographer October 27, 1936 DETAIL OF DOORWAY IN WING (FROM NORTHEAST 10:15 a.m.) oldest part - "Level Green", Charles Town, Jefferson County, WV

  4. 76 FR 19970 - West Virginia Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-11

    [email protected] , or via facsimile to 304-637-0582. All comments, including names and addresses when... Sycamore Street, Elkins, WV 26241; (304) 636-1800; E-mail [email protected] . Individuals who use...

  5. 1. NORTHWEST FRONT, SOUTHWEST SIDE (SPRING HOUSE IN FOREGROUND; BATH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. NORTHWEST FRONT, SOUTHWEST SIDE (SPRING HOUSE IN FOREGROUND; BATH HOUSE AT REAR) (4 x 5 negative; 5 x 7 print) - Salt Sulphur Springs, Spring House, U.S. Route 219, Salt Sulphur Springs, Monroe County, WV

  6. 1. LOOKING NORTH, SHOWING IODINE SPRING (FOREGROUND), SALT SULPHUR SPRING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. LOOKING NORTH, SHOWING IODINE SPRING (FOREGROUND), SALT SULPHUR SPRING (LEFT BACKGROUND), AND TWIN COTTAGES (UPPER RIGHT) (4 x 5 negative; 5 x 7 print) - Salt Sulpher Springs, U.S. Route 219, Salt Sulphur Springs, Monroe County, WV

  7. 2. SHOWING (LEFT TO RIGHT) CHAPEL, STORE BUILDING, SPRING HOUSE, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. SHOWING (LEFT TO RIGHT) CHAPEL, STORE BUILDING, SPRING HOUSE, AND BATH HOUSE, SOUTHEAST FACADES (4 x 5 negative; 5 x 7 print) - Salt Sulpher Springs, U.S. Route 219, Salt Sulphur Springs, Monroe County, WV

  8. GANTRY SIGNAL EAST OF TOWER AT MILEPOST 203.0, LOOKING WEST, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    GANTRY SIGNAL EAST OF TOWER AT MILEPOST 203.0, LOOKING WEST, EQUIPPED WITH B&O COLOR-POSITION-LIGHT SIGNAL HEAD FOR WESTBOUND TRAINS. - Baltimore & Ohio Railroad, Z Tower, State Route 46, Keyser, Mineral County, WV

  9. SIGNAL BRIDGE WEST OF TOWER AT MILEPOST 203.2, LOOKING WEST, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    SIGNAL BRIDGE WEST OF TOWER AT MILEPOST 203.2, LOOKING WEST, EQUIPPED WITH B&O COLOR-POSITION-LIGHT SIGNAL HEADS FOR EASTBOUND TRAINS. - Baltimore & Ohio Railroad, Z Tower, State Route 46, Keyser, Mineral County, WV

  10. DETAIL OF BEEHIVE COKE OVEN DOOR, LOOKING NORTH; NOTE FIREBRICK ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL OF BEEHIVE COKE OVEN DOOR, LOOKING NORTH; NOTE FIRE-BRICK ARCH AND IRON JAMB AND SILL - Nuttallburg Mine Complex, Coke Ovens, North side of New River, 2.7 miles upstream from Fayette Landing, Lookout, Fayette County, WV

  11. 4. Photocopied August 1975 from The Evolution of Modern Band ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Photocopied August 1975 from The Evolution of Modern Band Saw Mills for Sawing Logs, Dewitt Clinton Prescott, 1910. THREE-BLOCK LOG CARRIAGE. *NOTE* 4'x 5' NEGATIVE - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  12. 3. Photocopied August 1975 from The Evolution of Modern Band ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Photocopied August 1975 from The Evolution of Modern Band Saw Mills for Sawing Logs, Dewitt Clinton Prescott, 1910. VIEW OF BAND SAW. *NOTE* 4'x 5' NEGATIVE - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  13. 1. LOOKING WEST TOWARD OIL/CLEANING SUPPLY BUILDING (SIDING AND ROOF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. LOOKING WEST TOWARD OIL/CLEANING SUPPLY BUILDING (SIDING AND ROOF VISIBLE TO THE LEFT); GAS PUMP SHED IN CENTER (IN SHADOWS). - Standard Lime & Stone Quarry, Oil-Cleaning Supply Building, County Route 27, Millville, Jefferson County, WV

  14. 12. Credit WS. Basement of Mill, showing wooden flywheels to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Credit WS. Basement of Mill, showing wooden flywheels to water wheel and Fairbanks. Morse 20 hp, 350 rpm diesel engine, patented April 20, 1920. - Bunker Hill Mill, County Route 26, Bunker Hill, Berkeley County, WV

  15. Pegylation of Magnetically Oriented Lipid Bilayers

    NASA Astrophysics Data System (ADS)

    King, Valencia; Parker, Margaret; Howard, Kathleen P.

    2000-01-01

    We report NMR data for magnetically oriented phospholipid bilayers which have been doped with a lipid derivatized with a polyethylene glycol polymer headgroup to stabilize samples against aggregation. 13C, 31P, and 2H NMR data indicate that the incorporation of PEG2000-PE (1% molar to DMPC) does not interfere with the orientation properties of bicelles prepared at 25% w/v with or without the presence of lanthanide. Bicelles prepared at 10% w/v are also shown to orient when PEG2000-PE is added. The addition of PEG2000-PE to cholesterol-containing, lanthanide-flipped bicelles is shown to inhibit sample phase separation and improve spectral quality. Furthermore, the addition of PEG2000-PE to high w/v bicelles (40% w/v) is demonstrated to lead to an increase in overall sample order.

  16. Marketplace strategy contract.

    DOT National Transportation Integrated Search

    2014-02-25

    The Heartland Intermodal Gateway (HIG) in Prichard, WV is dedicated to providing a : corridor for double-stacked rail across what is known as the heartland of the United : States. The Rahall Transportation Institute (RTI) was tasked with assist...

  17. 32. Credit JTL. Exterior transformer bank; note lightning arrestors removed ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    32. Credit JTL. Exterior transformer bank; note lightning arrestors removed from pad and smaller arrestors installed on transformers and in area near air switches. - Dam No. 4 Hydroelectric Plant, Potomac River, Martinsburg, Berkeley County, WV

  18. 30 CFR 22.4 - Application procedures and requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Administration, Approval and Certification Center, 765 Technology Drive, Triadelphia, WV 26059, together with the...) Identification of components or features of the product that are critical to the safety of the product; and (4...

  19. 30 CFR 20.14 - Instructions for handling future changes in lamp design.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., 765 Technology Drive, Triadelphia, WV 26059, requesting an extension of the original approval and... that are critical to the safety of the product; and (iv) All documentation, including drawings and...

  20. 30 CFR 22.11 - Instructions on handling future changes in design.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Certification Center, 765 Technology Drive, Triadelphia, WV 26059, requesting an extension of the original... that are critical to the safety of the product; and (iv) All documentation, including drawings and...

  1. 30 CFR 23.14 - Instructions for handling future changes in design.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., 765 Technology Drive, Triadelphia, WV 26059, requesting an extension of the original approval and... that are critical to the safety of the product; and (iv) All documentation, including drawings and...

  2. 30 CFR 23.14 - Instructions for handling future changes in design.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., 765 Technology Drive, Triadelphia, WV 26059, requesting an extension of the original approval and... that are critical to the safety of the product; and (iv) All documentation, including drawings and...

  3. 30 CFR 22.11 - Instructions on handling future changes in design.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Certification Center, 765 Technology Drive, Triadelphia, WV 26059, requesting an extension of the original... that are critical to the safety of the product; and (iv) All documentation, including drawings and...

  4. 30 CFR 22.4 - Application procedures and requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Administration, Approval and Certification Center, 765 Technology Drive, Triadelphia, WV 26059, together with the...) Identification of components or features of the product that are critical to the safety of the product; and (4...

  5. 30 CFR 23.14 - Instructions for handling future changes in design.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., 765 Technology Drive, Triadelphia, WV 26059, requesting an extension of the original approval and... that are critical to the safety of the product; and (iv) All documentation, including drawings and...

  6. 30 CFR 22.11 - Instructions on handling future changes in design.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Certification Center, 765 Technology Drive, Triadelphia, WV 26059, requesting an extension of the original... that are critical to the safety of the product; and (iv) All documentation, including drawings and...

  7. 30 CFR 22.4 - Application procedures and requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Administration, Approval and Certification Center, 765 Technology Drive, Triadelphia, WV 26059, together with the...) Identification of components or features of the product that are critical to the safety of the product; and (4...

  8. 30 CFR 23.14 - Instructions for handling future changes in design.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., 765 Technology Drive, Triadelphia, WV 26059, requesting an extension of the original approval and... that are critical to the safety of the product; and (iv) All documentation, including drawings and...

  9. 30 CFR 22.4 - Application procedures and requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Administration, Approval and Certification Center, 765 Technology Drive, Triadelphia, WV 26059, together with the...) Identification of components or features of the product that are critical to the safety of the product; and (4...

  10. 30 CFR 23.14 - Instructions for handling future changes in design.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., 765 Technology Drive, Triadelphia, WV 26059, requesting an extension of the original approval and... that are critical to the safety of the product; and (iv) All documentation, including drawings and...

  11. 30 CFR 22.11 - Instructions on handling future changes in design.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Certification Center, 765 Technology Drive, Triadelphia, WV 26059, requesting an extension of the original... that are critical to the safety of the product; and (iv) All documentation, including drawings and...

  12. Detail view of gauges that record pressure of gas coming ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of gauges that record pressure of gas coming into the engine house. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  13. Detail view of gauges that record pressure of gas leaving ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of gauges that record pressure of gas leaving the engine house. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  14. View southwest, east front, interior bays, and north end ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View southwest, east front, interior bays, and north end - Abraham Cyrus Farmstead, Equipment Shed, About 320 feet south-southwest of farmhouse at 3271 Cyrus Road (County Road 1/6), Cyrus, Wayne County, WV

  15. 40. William E. Barrett, Photographer, August 1975. ROOF OF POWERHOUSE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    40. William E. Barrett, Photographer, August 1975. ROOF OF POWERHOUSE SHOWING HOPPERS FOR SAWDUST USED TO FIRE STEAM BOILERS. DUCTS AT LEFT LEAD FROM PLANNING MILL AND OTHER MANUFACTURING OPERATIONS. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  16. 30 CFR 19.13 - Instructions for handling future changes in lamp design.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC CAP LAMPS § 19.13 Instructions for..., Approval and Certification Center, 765 Technology Drive, Triadelphia, WV 26059, requesting an extension of...

  17. 30 CFR 20.14 - Instructions for handling future changes in lamp design.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MINE LAMPS OTHER THAN STANDARD CAP..., 765 Technology Drive, Triadelphia, WV 26059, requesting an extension of the original approval and...

  18. 30 CFR 19.3 - Application procedures and requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC CAP LAMPS § 19.3 Application procedures and requirements... Certification Center, 765 Technology Drive, Triadelphia, WV 26059, together with the required drawings, one...

  19. 30 CFR 20.3 - Application procedures and requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MINE LAMPS OTHER THAN STANDARD CAP LAMPS § 20.3... Certification Center, 765 Technology Drive, Triadelphia, WV 26059, together with the required drawings, one...

  20. Mumps Cases and Outbreaks

    MedlinePlus

    ... Providers Laboratory Testing for Mumps Infection Specimen Collection, Storage, and ... SC, TN, TX, UT, VA, VT, WA, WI, and WV **Preliminary data reported to CDC. Mumps outbreaks are not reportable. * ...

  1. 60. Photocopy of photograph, no date. DETAIL OF SWITCHBOARD. (Courtesy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    60. Photocopy of photograph, no date. DETAIL OF SWITCHBOARD. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files, Properties-Buildings and Equipment listing) - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  2. 53. Photocopy of photograph, c. 1946. GENERAL INTERIOR VIEW OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    53. Photocopy of photograph, c. 1946. GENERAL INTERIOR VIEW OF GENERATOR ROOM. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files, Dam No. 5 listing) - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  3. 61. Photocopy of photograph, c. 1949. DETAIL OF SWITCHBOARD WITH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    61. Photocopy of photograph, c. 1949. DETAIL OF SWITCHBOARD WITH MODIFICATIONS. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files, Dam No. 5 listing) - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  4. 78 FR 11229 - Investigations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-15

    ... purpose of each of the investigations is to determine whether the workers are eligible to apply for...-Stop). 82388 Aleris Recycling Bens Run, Friendly, WV 01/30/13 01/29/13 LLC (Union). 82389 Elster AMCO...

  5. TOWER, WEST ELEVATION, SHOWING CONNECTION PIPES FOR TURNOUTS 22 (FOREGROUND) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    TOWER, WEST ELEVATION, SHOWING CONNECTION PIPES FOR TURNOUTS 22 (FOREGROUND) AND 24. NOTE “LAZY JACK” TEMPERATURE COMPENSATOR IN FOREGROUND. - Baltimore & Ohio Railroad, Z Tower, State Route 46, Keyser, Mineral County, WV

  6. 32 CFR 634.54 - List of State Driver's License Agencies.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Vehicles, 1800 Washington Street, East, Charleston, WV 25317, (304) 348-2719. Wisconsin: Department of Transportation Reciprocity and Permits, P.O. Box 7908, Madison, WI 53707, (608) 266-2585. Wyoming: Department of...

  7. 32 CFR 634.54 - List of State Driver's License Agencies.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Vehicles, 1800 Washington Street, East, Charleston, WV 25317, (304) 348-2719. Wisconsin: Department of Transportation Reciprocity and Permits, P.O. Box 7908, Madison, WI 53707, (608) 266-2585. Wyoming: Department of...

  8. 32 CFR 634.54 - List of State Driver's License Agencies.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Vehicles, 1800 Washington Street, East, Charleston, WV 25317, (304) 348-2719. Wisconsin: Department of Transportation Reciprocity and Permits, P.O. Box 7908, Madison, WI 53707, (608) 266-2585. Wyoming: Department of...

  9. 32 CFR 634.54 - List of State Driver's License Agencies.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Vehicles, 1800 Washington Street, East, Charleston, WV 25317, (304) 348-2719. Wisconsin: Department of Transportation Reciprocity and Permits, P.O. Box 7908, Madison, WI 53707, (608) 266-2585. Wyoming: Department of...

  10. 29 CFR 1601.74 - Designated and notice agencies.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Relations Commission Madison (WI) Equal Opportunities Commission Maine Human Rights Commission Maryland... (WV) Human Rights Commission Wichita Falls (TX) Human Relations Commission Wisconsin Equal Rights Division, Department of Industry, Labor and Human Relations Wisconsin State Personnel Commission 13 13 The...

  11. 45. William E. Barrett, Photographer, August 1975. EARLY STEAM GENERATING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    45. William E. Barrett, Photographer, August 1975. EARLY STEAM GENERATING UNIT USED TO PRODUCE ELECTRICITY FOR MANUFACTURING OPERATIONS AND FOR THE TOWN OF RAINELLE. STEAM ENGINE IS A HAMILTON CORLISS. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  12. 1. LOOKING SOUTHWEST TOWARD NORTH AND WEST SIDES OF OFFICE; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. LOOKING SOUTHWEST TOWARD NORTH AND WEST SIDES OF OFFICE; LABORATORY AND ELECTRICITY SUPPLY HOUSE TO THE RIGHT. - Standard Lime & Stone Quarry, Office, County Route 27, Millville, Jefferson County, WV

  13. East yard, north elevation of car department tool house (converted ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    East yard, north elevation of car department tool house (converted from express car). - Chesapeake & Ohio Railroad, Thurmond Yards, East side New River, mouths of Arbuckle & Dunlop Circles, Thurmond, Fayette County, WV

  14. 6. VIEW EAST OF CEMENT PIER AND TRAFFIC DECK SUPPORT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. VIEW EAST OF CEMENT PIER AND TRAFFIC DECK SUPPORT SYSTEM; NOTE FLOOR BEAMS AND STRINGERS VIEWED FROM UNDERNEATH THE BRIDGE - Water Street Bridge, County Route 119/26, over Guyandotte River, Logan, Logan County, WV

  15. 76 FR 68378 - Approval and Promulgation of Air Quality Implementation Plans; District of Columbia, Maryland...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-04

    ...; Determinations of Attainment of the 1997 Fine Particle Standard for the Metropolitan Washington and Martinsburg...-Maryland-Virginia (DC-MD-VA) and Martinsburg-Hagerstown, West Virginia-Maryland (WV-MD) fine particle (PM 2...

  16. 15. STONE BURR MILL PROBABLY USED FOR GRINDING FEED. ONLY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. STONE BURR MILL PROBABLY USED FOR GRINDING FEED. ONLY REMAINING MILL MACHINERY William E. Barrett, photographer, 1973 - Thomas Shepherd's Grist Mill, High Street Vicinity, Shepherdstown, Jefferson County, WV

  17. Preparation and characterization of malonic acid cross-linked chitosan and collagen 3D scaffolds: an approach on non-covalent interactions.

    PubMed

    Mitra, Tapas; Sailakshmi, G; Gnanamani, A; Mandal, A B

    2012-05-01

    The present study emphasizes the influence of non-covalent interactions on the mechanical and thermal properties of the scaffolds of chitosan/collagen origin. Malonic acid (MA), a bifuncitonal diacid was chosen to offer non-covalent cross-linking. Three dimensional scaffolds was prepared using chitosan at 1.0% (w/v) and MA at 0.2% (w/v), similarly collagen 0.5% (w/v) and MA 0.2% (w/v) and characterized. Results on FT-IR, TGA, DSC, SEM and mechanical properties (tensile strength, stiffness, Young's modulus, etc.) assessment demonstrated the existence of non-covalent interaction between MA and chitosan/collagen, which offered flexibility and high strength to the scaffolds suitable for tissue engineering research. Studies using NIH 3T3 fibroblast cells suggested biocompatibility nature of the scaffolds. Docking simulation study further supports the intermolecular hydrogen bonding interactions between MA and chitosan/collagen.

  18. 22. INTERIOR, FIRST FLOOR, EAST SECTION, NORTHEAST ROOM, NORTHWEST CORNER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. INTERIOR, FIRST FLOOR, EAST SECTION, NORTHEAST ROOM, NORTHWEST CORNER (NOTE EXPOSED BRICK NOGGING) - Peter Burr House, Vicinity of State Route 9 & Ridge Road, Shenandoah Junction, Jefferson County, WV

  19. The Public Use Limitation in Eminent Domain: "Handley v. Cook."

    ERIC Educational Resources Information Center

    Grill, Donna P.

    1979-01-01

    It is time for the courts to rigorously scrutinize allegations of public use in order to protect the property rights of private individuals. Available from West Virginia Law Review, W.V.U. Law Center, Morgantown, WV 26506. (Author)

  20. 22. William E. Barrett, Photographer, August 1975. CHIPPER OR 'HOG' ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. William E. Barrett, Photographer, August 1975. CHIPPER OR 'HOG' FOR REDUCING SCRAPS TO WOOD CHIPS. HOUSING PARTIALLY REMOVED. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  1. 1. Photocopy of engraved flyer (from the collection of Dr. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Photocopy of engraved flyer (from the collection of Dr. Margaret Ballard, Union, West Virginia) H. Bartsch, engraver late 19th century AERIAL VIEW OF TOWN AND ADVERTISING SLOGANS - Red Sulphur Springs, Route 12, Salt Sulphur Springs, Monroe County, WV

  2. 13. View South, showing the remaining pier footings for the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. View South, showing the remaining pier footings for the steam engine water tower for the Chesapeake and Ohio Railroad. - Cotton Hill Station Bridge, Spanning New River at State Route 16, Cotton Hill, Fayette County, WV

  3. 2. GENERAL VIEW SHOWING SIMPSON CREEK BRIDGE WITH BRIDGEPORT LAMP ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. GENERAL VIEW SHOWING SIMPSON CREEK BRIDGE WITH BRIDGEPORT LAMP AND CHIMNEY COMPANY IN BACKGROUND. - Bridgeport Lamp Chimney Company, Simpson Creek Bridge, Spanning Simpson Creek, State Route 58 vicinity, Bridgeport, Harrison County, WV

  4. 35. INTERIOR VIEW, WHEELBRATORFRYE SHOT PEENER FOR REMOVAL OF RUST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    35. INTERIOR VIEW, WHEELBRATOR-FRYE SHOT PEENER FOR REMOVAL OF RUST AND SCALE; NOTE TOOLS ARE TUMBLED WITH BLASTED WITH LEAD SHOT TO CLEAN SURFACES - Warwood Tool Company, Foot of Nineteenth Street, Wheeling, Ohio County, WV

  5. 24. INTERIOR VIEW, WILLIAM GRAY AT SIZING GUAGE ADJACENT TO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    24. INTERIOR VIEW, WILLIAM GRAY AT SIZING GUAGE ADJACENT TO BRADLEY HAMMER; NOTE THIS IS THE SAME TOOL AS BEING FORGED ABOVE - Warwood Tool Company, Foot of Nineteenth Street, Wheeling, Ohio County, WV

  6. 10. INTERIOR VIEW OF EYE PRESS AREA, SAME AS ABOVE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. INTERIOR VIEW OF EYE PRESS AREA, SAME AS ABOVE WITH MEN AT WORK: CRAIG TSCHAPPAT, HEATER; JEFF MILLER, OPERATOR; JOHN TOTH, SAWMAN - Warwood Tool Company, Foot of Nineteenth Street, Wheeling, Ohio County, WV

  7. 78 FR 60020 - Proposed Collection: Comment Request for Voluntary Customer Satisfaction Surveys

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-30

    ... Voluntary Customer Satisfaction Surveys ACTION: Notice and request for comments. SUMMARY: The Department of... Treasury is soliciting comments concerning the Customer Satisfaction Survey. DATES: Written comments should..., WV 26106-1328, (304) 480- 8150. SUPPLEMENTARY INFORMATION: Title: Voluntary Customer Satisfaction...

  8. View of Harpers Ferry, station to right at end of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of Harpers Ferry, station to right at end of CSX Railroad Bridge. Taken from Maryland Heights Ridge from the east. - Baltimore & Ohio Railroad, Harpers Ferry Station, Potomac Street, Harpers Ferry, Jefferson County, WV

  9. 4. EASTBOUND VIEW. NORTH TRACK WAITING STATION ON LEFT. STATION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. EASTBOUND VIEW. NORTH TRACK WAITING STATION ON LEFT. STATION ON RIGHT. NOTE TUNNEL IN BACKGROUND. - Baltimore & Ohio Railroad, Harpers Ferry Station, Potomac Street, Harpers Ferry, Jefferson County, WV

  10. View of Harpers Ferry, station behind trees in lower right. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of Harpers Ferry, station behind trees in lower right. Taken from Maryland Heights Ridge from the east. - Baltimore & Ohio Railroad, Harpers Ferry Station, Potomac Street, Harpers Ferry, Jefferson County, WV

  11. 5. Double crib barn, main floor, 4th room from northeast, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Double crib barn, main floor, 4th room from northeast, southeast and southwest walls - Wilkins Farm, Barn, South side of Dove Hollow Road, 6000 feet east of State Route 259, Lost City, Hardy County, WV

  12. Spruce No. 1 Surface Mine Recommended Determination

    EPA Pesticide Factsheets

    This document explains the basis for the EPA Region III recommendation to withdraw the specification of Pigeonroost Branch, Oldhouse Branch and their tributaries within Logan County, WV as a disposal site for dredged or fill material.

  13. 30 CFR 19.3 - Application procedures and requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC CAP LAMPS § 19.3 Application procedures and requirements... Certification Center, 765 Technology Drive, Triadelphia, WV 26059, together with the required drawings, one...

  14. 30 CFR 19.13 - Instructions for handling future changes in lamp design.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC CAP LAMPS § 19.13 Instructions for..., Approval and Certification Center, 765 Technology Drive, Triadelphia, WV 26059, requesting an extension of...

  15. 30 CFR 19.3 - Application procedures and requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC CAP LAMPS § 19.3 Application procedures and requirements... Certification Center, 765 Technology Drive, Triadelphia, WV 26059, together with the required drawings, one...

  16. 30 CFR 20.14 - Instructions for handling future changes in lamp design.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MINE LAMPS OTHER THAN STANDARD CAP..., 765 Technology Drive, Triadelphia, WV 26059, requesting an extension of the original approval and...

  17. 30 CFR 20.3 - Application procedures and requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MINE LAMPS OTHER THAN STANDARD CAP LAMPS § 20.3... Certification Center, 765 Technology Drive, Triadelphia, WV 26059, together with the required drawings, one...

  18. 30 CFR 20.14 - Instructions for handling future changes in lamp design.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MINE LAMPS OTHER THAN STANDARD CAP..., 765 Technology Drive, Triadelphia, WV 26059, requesting an extension of the original approval and...

  19. 30 CFR 20.3 - Application procedures and requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MINE LAMPS OTHER THAN STANDARD CAP LAMPS § 20.3... Certification Center, 765 Technology Drive, Triadelphia, WV 26059, together with the required drawings, one...

  20. 30 CFR 19.3 - Application procedures and requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC CAP LAMPS § 19.3 Application procedures and requirements... Certification Center, 765 Technology Drive, Triadelphia, WV 26059, together with the required drawings, one...

  1. 30 CFR 19.13 - Instructions for handling future changes in lamp design.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC CAP LAMPS § 19.13 Instructions for..., Approval and Certification Center, 765 Technology Drive, Triadelphia, WV 26059, requesting an extension of...

  2. 30 CFR 19.3 - Application procedures and requirements.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC CAP LAMPS § 19.3 Application procedures and requirements... Certification Center, 765 Technology Drive, Triadelphia, WV 26059, together with the required drawings, one...

  3. 30 CFR 19.13 - Instructions for handling future changes in lamp design.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC CAP LAMPS § 19.13 Instructions for..., Approval and Certification Center, 765 Technology Drive, Triadelphia, WV 26059, requesting an extension of...

  4. 30 CFR 20.3 - Application procedures and requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MINE LAMPS OTHER THAN STANDARD CAP LAMPS § 20.3... Certification Center, 765 Technology Drive, Triadelphia, WV 26059, together with the required drawings, one...

  5. 30 CFR 20.3 - Application procedures and requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MINE LAMPS OTHER THAN STANDARD CAP LAMPS § 20.3... Certification Center, 765 Technology Drive, Triadelphia, WV 26059, together with the required drawings, one...

  6. 30 CFR 19.13 - Instructions for handling future changes in lamp design.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC CAP LAMPS § 19.13 Instructions for..., Approval and Certification Center, 765 Technology Drive, Triadelphia, WV 26059, requesting an extension of...

  7. 30 CFR 20.14 - Instructions for handling future changes in lamp design.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MINE LAMPS OTHER THAN STANDARD CAP..., 765 Technology Drive, Triadelphia, WV 26059, requesting an extension of the original approval and...

  8. 10 CFR 1008.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) National Energy Technology Laboratory, 3610 Collins Ferry Road, Morgantown, WV 26507-0800. (11) Oak Ridge..., financial transactions, medical history, and criminal or employment history, and that contains that...

  9. Martinsburg Plant Upgrade Helps Waters Near and Far

    EPA Pesticide Factsheets

    With key financial assistance from EPA, the City of Martinsburg, W.V., has revamped its wastewater treatment plant to achieve steep pollution reductions that will benefit local creeks and the Chesapeake Bay.

  10. 34. View of pier 3, showing supporting main anchor arm ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    34. View of pier 3, showing supporting main anchor arm and cantilever arm spans, as seen from shore near pier 4, looking north - Williamstown-Marietta Bridge, Spanning Ohio River between Williamstown & Marietta, Williamstown, Wood County, WV

  11. 22. View showing main anchor arm, as viewed from main ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. View showing main anchor arm, as viewed from main cantilever arm looking south. Note upper chord eyebar arrangement. - Williamstown-Marietta Bridge, Spanning Ohio River between Williamstown & Marietta, Williamstown, Wood County, WV

  12. 76 FR 174 - International Business Machines (IBM), Global Sales Operations Organization, Sales and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-03

    ...] International Business Machines (IBM), Global Sales Operations Organization, Sales and Distribution Business Manager Roles; One Teleworker Located in Charleston, WV; International Business Machines (IBM), Global Sales Operations Organization, Sales and Distribution Business Unit, Relations Analyst and Band 8...

  13. 7 CFR 353.3 - Where service is offered.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ..., MN, IL, IN, OH, MI, WV. Southeastern, 3505 25th Avenue, Building 1, North, Gulfport, MS 39501 FL, AL... listed in 50 CFR 17.12 or 23.23: Mobile, AL Savannah, GA Baltimore, MD Gulfport, MS Wilmington and...

  14. 14. Photocopy of photograph (Original in the collection of Baltimore ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Photocopy of photograph (Original in the collection of Baltimore and Ohio Railroad) Unknown, Photographer, November 1956 PERSPECTIVE VIEW OF EAST (FRONT) AND SOUTH SIDE - John Brown Fort, Shenandoah Street, Harpers Ferry, Jefferson County, WV

  15. 15. General view of complex from the north, (includes Roeder ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. General view of complex from the north, (includes Roeder House to the right and to the left (east), at end of street, John Brown's fort). - Roeder Store, Potomac Street, Harpers Ferry, Jefferson County, WV

  16. 13. William E. Barrett, Photographer, August 1975. INTERIOR OF SAWMILL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. William E. Barrett, Photographer, August 1975. INTERIOR OF SAWMILL LOOKING EAST. LOGS FOR CENTER MILL ROLLED RIGHT TO CONVEYOR WHICH CARRIED THEM TO SECOND SLOPING DECK. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  17. 11. William E. Barrett, Photographer, August 1975. INTERIOR OF SAWMILL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. William E. Barrett, Photographer, August 1975. INTERIOR OF SAWMILL SHOWING STEAM CYLINDER AND PISTON ROD OF LEFT-HAND MILL (LEFT) AND HOUSING OF CENTER BANDSAW. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  18. 16. William E. Barrett, Photographer, August 1975. CENTER MILL (RIGHTHANDED) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. William E. Barrett, Photographer, August 1975. CENTER MILL (RIGHT-HANDED) WITH CARRIAGE TRACKS AND BANDSAW HOUSING INTACT. LOG CLAMPS ON THIS CARRIAGE WERE PNEUMATICALLY OPERATED. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  19. 8. William E. Barrett, Photographer, August 1975. LOG DOCK AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. William E. Barrett, Photographer, August 1975. LOG DOCK AND PARTIALLY DEMOLISHED JACKSLIP USED FOR HAULING LOGS UP TO SAWMILL. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  20. 6. William E. Barrett, Photographer, 1975. GENERAL VIEW LOOKING EAST. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. William E. Barrett, Photographer, 1975. GENERAL VIEW LOOKING EAST. SAWMILL ON RIGHT. SECONDARY WOODWORKING SHOPS ON LEFT PARTIALLY DEMOLISHED. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  1. 3. CASTIRON BOLSTER MARKED 'B & O RR CO. 1866' ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. CAST-IRON BOLSTER MARKED 'B & O RR CO. 1866' PROTECTING DOORWAY TO MACHINE SHOP. - Baltimore & Ohio Railroad, Martinsburg Machine Shop, West Side of Tuscarora Creek Opposite East End of Race Street, Martinsburg, Berkeley County, WV

  2. General view of thurmond, looking east from tracks, showing signal ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view of thurmond, looking east from tracks, showing signal tower in foreground and depot in background. - Chesapeake & Ohio Railroad, Thurmond Yards, East side New River, mouths of Arbuckle & Dunlop Circles, Thurmond, Fayette County, WV

  3. General view of thurmond, looking west along north side of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view of thurmond, looking west along north side of tracks, showing commercial buildings and signal tower left of center. - Chesapeake & Ohio Railroad, Thurmond Yards, East side New River, mouths of Arbuckle & Dunlop Circles, Thurmond, Fayette County, WV

  4. Improved Nissl method to stain formaldehyde or glutaraldehyde-fixed material.

    PubMed

    Böck, P

    1979-05-15

    Nissl staining of paraffin sections from formaldehyde- or glutaraldehyde-fixed specimens is significantly intensified when sections are kept in a 50% (w/v) aqueous solution of potassium metabisulfite before being stained by a conventional Nissl method.

  5. 77 FR 39322 - Companies Holding Certificates of Authority as Acceptable Sureties on Federal Bonds and as...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-02

    ..., WI. INCORPORATED IN: Michigan. COLONIAL AMERICAN CASUALTY AND SURETY COMPANY (NAIC 34347) BUSINESS..., PA, RI, SC, SD, TN, TX, UT, VT, VA, WA, WV, WI, WY. INCORPORATED IN: Maryland. COLONIAL SURETY...

  6. 78 FR 39439 - Companies Holding Certificates of Authority as Acceptable Sureties on Federal Bonds and as...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-01

    ...: Michigan. COLONIAL AMERICAN CASUALTY AND SURETY COMPANY (NAIC 34347) BUSINESS ADDRESS: 1400 AMERICAN LANE..., UT, VT, VA, WA, WV, WI, WY. INCORPORATED IN: Maryland. COLONIAL SURETY COMPANY (NAIC 10758) BUSINESS...

  7. 75 FR 38191 - Companies Holding Certificates of Authority as Acceptable Sureties on Federal Bonds and as...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-01

    .... COLONIAL AMERICAN CASUALTY AND SURETY COMPANY (NAIC 34347) BUSINESS ADDRESS: 1400 AMERICAN LANE, TOWER I..., WA, WV, WI, WY. INCORPORATED IN: Maryland. COLONIAL SURETY COMPANY (NAIC 10758) BUSINESS ADDRESS: 50...

  8. 14. Credit PED. Downstream elevation, near completion, showing tail race ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Credit PED. Downstream elevation, near completion, showing tail race and trestle used to carry excavated rock and construction materials across tail race. Photo c. 1909. - Dam No. 4 Hydroelectric Plant, Potomac River, Martinsburg, Berkeley County, WV

  9. Topical Hazard Evaluation Program Procedural Guide.

    DTIC Science & Technology

    1982-01-01

    conditions and are percent (w/v) Oil of tion reaction under test not expected to cause a Bergamot solution conditions. photochemical irritation...photochemical skin irritant ( Bergamot oil). d. All compounds-are handled with caution. Current test procedures cannot eliminate the possibility of individual...percent ethyl alcohol. One additional compound applied along with the test compounds is a 10 percent solution (w/v) of Bergamot oil" in 95 percent ethyl

  10. Deficient Differentiation of Mast Cells in the Skin of mi/mi Mice

    PubMed Central

    Kasugai, Tsutomu; Oguri, Kayoko; Jippo-Kanemoto, Tomoko; Morimoto, Masahiro; Yamatodani, Atsushi; Yoshida, Keiichi; Ebi, Yoshitaka; Isozaki, Koji; Tei, Hideki; Tsujimura, Tohru; Nomura, Shintaro; Okayama, Minoru; Kitamura, Yukihiko

    1993-01-01

    The staining property of skin mast cells changed from Alcian blue+/berberine sulfate- to Alcian blue +/berberine sulfate+ in the skin of normal (+/+) and Wv/Wv mice. In contrast, this change did not occur in the skin of mi/mi mice. Heparin content and histamine content per a mi/mi skin mast cell were estimated to be 34% and 18% those of a +/+ skin mast cell, respectively. The low heparin content of mi/mi skin mast cells seemed to be consistent with the Alcian blue+/berberine sulfate- staining property. Expression of genes encoding mast cell-specific proteolytic enzymes was examined by Northern blotting and in situ hybridization. Messenger RNA of mast cell carboxypeptidase A was expressed most of all by +/+, WV Wv/W+ and mi/mi skin mast cells, but mRNA of mouse mast cell protease (MMCP)-6 was expressed by approximately a half of +/+ and Wv/Wv skin mast cells and by only 3% of mi/mi skin mast cells. A significant amount of MMCP-2 mRNA was not expressed in the skin of all +/+, Wv/Wv and mi/mi mice. This shows the presence of at least three phenotypes in skin mast cells of mice: berberine sulfate+/MMCP-6+, berberine sulfate+/MMCP-6-, and berberine sulfate-/ MMCP-6-. The in situ hybridization of mRNA of mast cell-specific proteolytic enzymes seemed to be useful to describe abnormalities of mast cell differentiation in the skin of mi/mi mice. ImagesFigure 4Figure 5 PMID:8238251

  11. 24. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    24. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #397508, 'Women weeding in the one-year old red spruce seedlings at the Parsons Nursery at Parsons, W. Va. Women are used for weeding here because of the dexterity of their hands. They are paid 40 cents an hour'), B. W. Muir, 1940. VIEW NORTHEAST, PACKING BUILDING IN BACKGROUND, WOMEN WEEDING. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  12. Rheological behavior and stability of ciprofloxacin suspension: Impact of structural vehicles and flocculating agent.

    PubMed

    Moghimipour, Eskandar; Rezaee, Saeed; Salimi, Anayatollah; Asadi, Elham; Handali, Somayeh

    2013-07-01

    Ciprofloxacin is a fluoroquinolone and is used against a broad spectrum of gram-negative and gram-positive bacteria. The aim of the study is to investigate the effect of structural vehicles and other formulating factors on physical stability and rheological behavior of ciprofloxacin suspension. To formulate the suspensions, the effect of glycerin and polysorbate 80 as wetting agents was evaluated. Then to achieve controlled flocculation, different concentrations of sodium chloride and calcium chloride were added. After choosing suitable wetting and flocculating agents, structural vehicles such as sodium carboxyl methyl cellulose (NaCMC), hydroxypropylmethylcellulose (HPMC) and Veegum were evaluated. Physical stability parameters such as sedimentation volume, the degree of flocculation and the ease of redispersion of the suspensions and growth of crystals were evaluated. After incorporation of structural vehicles, the rheological properties of formulations containing were also studied to find out their rheological behavior. According to the results, suspension containing glycerin (0.2% w/v) and sodium chloride (0.05% w/v) as wetting agent and flocculating agent, respectively, were the most stable formulations regarding their F and N. Microscopic observations showed the growth of crystals in ciprofloxacin suspension in formulation without excipients and the minimum amount of crystal growth was seen in suspension containing NaCMC (0.25% w/v), Veegum (0.1% w/v) and NaCl (0.05% w/v). Rheological studies showed that almost all of the formulations had psuedoplastic behavior with different degree of thixotropy. The formulation containing NaCMC (0.25% w/v), Veegum (0.1% w/v) and NaCl (0.05% w/v) was the most stable formulation. It may be concluded that by altering the amount ratios of formulation factors, the best rheological behavior and the most proper thixotropy may be achieved.

  13. Rheological behavior and stability of ciprofloxacin suspension: Impact of structural vehicles and flocculating agent

    PubMed Central

    Moghimipour, Eskandar; Rezaee, Saeed; Salimi, Anayatollah; Asadi, Elham; Handali, Somayeh

    2013-01-01

    Ciprofloxacin is a fluoroquinolone and is used against a broad spectrum of gram-negative and gram-positive bacteria. The aim of the study is to investigate the effect of structural vehicles and other formulating factors on physical stability and rheological behavior of ciprofloxacin suspension. To formulate the suspensions, the effect of glycerin and polysorbate 80 as wetting agents was evaluated. Then to achieve controlled flocculation, different concentrations of sodium chloride and calcium chloride were added. After choosing suitable wetting and flocculating agents, structural vehicles such as sodium carboxyl methyl cellulose (NaCMC), hydroxypropylmethylcellulose (HPMC) and Veegum were evaluated. Physical stability parameters such as sedimentation volume, the degree of flocculation and the ease of redispersion of the suspensions and growth of crystals were evaluated. After incorporation of structural vehicles, the rheological properties of formulations containing were also studied to find out their rheological behavior. According to the results, suspension containing glycerin (0.2% w/v) and sodium chloride (0.05% w/v) as wetting agent and flocculating agent, respectively, were the most stable formulations regarding their F and N. Microscopic observations showed the growth of crystals in ciprofloxacin suspension in formulation without excipients and the minimum amount of crystal growth was seen in suspension containing NaCMC (0.25% w/v), Veegum (0.1% w/v) and NaCl (0.05% w/v). Rheological studies showed that almost all of the formulations had psuedoplastic behavior with different degree of thixotropy. The formulation containing NaCMC (0.25% w/v), Veegum (0.1% w/v) and NaCl (0.05% w/v) was the most stable formulation. It may be concluded that by altering the amount ratios of formulation factors, the best rheological behavior and the most proper thixotropy may be achieved. PMID:24083201

  14. Productivity Measurement and Analysis of Airborne Weapons Maintenance Plans Performed by the Weapons Support Directorate, Pacific Missile Test Center, Pt. Mugu.

    DTIC Science & Technology

    1987-12-01

    FM__KWJW~j’JVx W-V WWv Wu M WV b7’ II. LIT’rIEK REVI, AND TD .ORZTICAL F MW A. WHAT IS PRODUCTIVITY? 1. Productivity Definod The definition of...Implementing the Manpower Budget And Workgd Forecasting System The implementation of the system designed in Step 9. Step 12 - Implement ihQ inaAn MtpQx

  15. Prevalence and Geographic Variations of Polypharmacy Among West Virginia Medicaid Beneficiaries.

    PubMed

    Feng, Xue; Tan, Xi; Riley, Brittany; Zheng, Tianyu; Bias, Thomas K; Becker, James B; Sambamoorthi, Usha

    2017-11-01

    West Virginia (WV) residents are at high risk for polypharmacy given its considerable chronic disease burdens. To evaluate the prevalence, correlates, outcomes, and geographic variations of polypharmacy among WV Medicaid beneficiaries. In this cross-sectional study, we analyzed 2009-2010 WV Medicaid fee-for-service (FFS) claims data for adults aged 18-64 (N=37,570). We defined polypharmacy as simultaneous use of drugs from five or more different drug classes on a daily basis for at least 60 consecutive days in one year. Multilevel logistic regression was used to explore the individual- and county-level factors associated with polypharmacy. Its relationship with healthcare utilization was assessed using negative binomial regression and logistic regression. The univariate local indicators of spatial association method was applied to explore spatial patterns of polypharmacy in WV. The prevalence of polypharmacy among WV Medicaid beneficiaries was 44.6%. High-high clusters of polypharmacy were identified in southern WV, indicating counties with above-average prevalence surrounded by counties with above-average prevalence. Polypharmacy was associated with being older, female, eligible for Medicaid due to cash assistance or medical eligibility, having any chronic conditions or more chronic conditions, and living in a county with lower levels of education. Polypharmacy was associated with more hospitalizations, emergency department visits, and outpatient visits, as well as higher non-drug medical expenditures. Polypharmacy was prevalent among WV Medicaid beneficiaries and was associated with substantial healthcare utilization and expenditures. The clustering of high prevalence of polypharmacy in southern WV may suggest targeted strategies to reduce polypharmacy burden in these areas.

  16. Weak measurements measure probability amplitudes (and very little else)

    NASA Astrophysics Data System (ADS)

    Sokolovski, D.

    2016-04-01

    Conventional quantum mechanics describes a pre- and post-selected system in terms of virtual (Feynman) paths via which the final state can be reached. In the absence of probabilities, a weak measurement (WM) determines the probability amplitudes for the paths involved. The weak values (WV) can be identified with these amplitudes, or their linear combinations. This allows us to explain the ;unusual; properties of the WV, and avoid the ;paradoxes; often associated with the WM.

  17. Katrina Historical Page - Office of Satellite and Product Operations

    Science.gov Websites

    » Disclaimer » Web Linking Policy » Use of Data and Products » FAQs: Imagery Contact Us Services Argos DCS . Floater Imagery August 28/1745Z to 29/0245Z: Image: AVN | BD | FT | IR | IR2 | JSL | RB | RGB | VIS | WV Image (w/ Latitude & Longitude): AVN | BD | FT | IR | IR2 | JSL | RB | RGB | VIS | WV Loop: AVN | BD

  18. In vitro efficacy of a honey-based gel against canine clinical isolates of Staphylococcus pseudintermedius and Malassezia pachydermatis.

    PubMed

    Oliveira, Ana M P; Devesa, Joana S P; Hill, Peter B

    2018-03-22

    Staphylococcus pseudintermedius and Malassezia pachydermatis are important agents in canine pyoderma and otitis. Determine the in vitro efficacy of a honey-based gel (HBO) against meticillin-susceptible S. pseudintermedius (MSSP), meticillin-resistant S. pseudintermedius (MRSP) and M. pachydermatis, by minimum bactericidal concentration (MBC), minimum fungicidal concentration (MFC) and time-kill assay (TKA). Efficacy of the product's honey component (HO) also was evaluated. Sixty S. pseudintermedius and 10 M. pachydermatis canine isolates were selected. All isolates were tested against serial dilutions of an HBO containing 40% HO (40%, 20%, 10%, 5% and 2.5% w/v) and HO alone (undiluted, 40%, 20%, 10%, 5% and 2.5% w/v). Microbroth assay followed by subculture was used to determine MBC and MFC. The same protocol was applied after product exposure to catalase. A well-diffusion assay for S. pseudintermedius was used to generate inhibition zones. A TKA for 10 isolates of S. pseudintermedius and 10 isolates of M. pachydermatis was performed. MBC was 20% w/v (5-20% w/v) for HBO and HO. HBO had lower MBC values when compared to HO (P = 0.003). No statistical difference was observed between MSSP/MRSP isolates (HBO P = 0.757, HO P = 0.743). Only HO was affected by catalase (P = 0.015). MFC for HBO was 10% w/v (5-10% w/v) and 40% w/v for HO (20-≥40% w/v). All isolates were killed after 4 h of exposure. Staphylococcus pseudintermedius and M. pachydermatis are susceptible to the HBO and these results can be used for future clinical trials. © 2018 ESVD and ACVD.

  19. A Mouse Model to Investigate Postmenopausal Biology as an Etiology of Ovarian Cancer Risk

    DTIC Science & Technology

    2006-11-01

    Wv mice and genetic alterations such as p53, pten, or p27kip1, which are found in human ovarian cancer. 2. Body: Research Progress In the first year...press (Yang et al., Am. J. Pathology 2007). To collaborate with the mouse model study, we have also examined human ovaries obtained from prophylactic...results in the coming years. Xu, Xiangxi, Ph.D. 8 3. Key Research Accomplishments (1) Further verify the relevance of the Wv mouse model to human

  20. WorldView-2 and the evolution of the DigitalGlobe remote sensing satellite constellation: introductory paper for the special session on WorldView-2

    NASA Astrophysics Data System (ADS)

    Anderson, Neal T.; Marchisio, Giovanni B.

    2012-06-01

    Over the last decade DigitalGlobe (DG) has built and launched a series of remote sensing satellites with steadily increasing capabilities: QuickBird, WorldView-1 (WV-1), and WorldView-2 (WV-2). Today, this constellation acquires over 2.5 million km2 of imagery on a daily basis. This paper presents the configuration and performance capabilities of each of these satellites, with emphasis on the unique spatial and spectral capabilities of WV-2. WV-2 employs high-precision star tracker and inertial measurement units to achieve a geolocation accuracy of 5 m Circular Error, 90% confidence (CE90). The native resolution of WV-2 is 0.5 m GSD in the panchromatic band and 2 m GSD in 8 multispectral bands. Four of the multispectral bands match those of the Landsat series of satellites; four new bands enable novel and expanded applications. We are rapidly establishing and refreshing a global database of very high resolution (VHR) 8-band multispectral imagery. Control moment gyroscopes (CMGs) on both WV-1 and WV-2 improve collection capacity and provide the agility to capture multi-angle sequences in rapid succession. These capabilities result in a rich combination of image features that can be exploited to develop enhanced monitoring solutions. Algorithms for interpretation and analysis can leverage: 1) broader and more continuous spectral coverage at 2 m resolution; 2) textural and morphological information from the 0.5 m panchromatic band; 3) ancillary information from stereo and multi-angle collects, including high precision digital elevation models; 4) frequent revisits and time-series collects; and 5) the global reference image archives. We introduce the topic of creative fusion of image attributes, as this provides a unifying theme for many of the papers in this WV-2 Special Session.

  1. Assessment of Pansharpening Methods Applied to WorldView-2 Imagery Fusion.

    PubMed

    Li, Hui; Jing, Linhai; Tang, Yunwei

    2017-01-05

    Since WorldView-2 (WV-2) images are widely used in various fields, there is a high demand for the use of high-quality pansharpened WV-2 images for different application purposes. With respect to the novelty of the WV-2 multispectral (MS) and panchromatic (PAN) bands, the performances of eight state-of-art pan-sharpening methods for WV-2 imagery including six datasets from three WV-2 scenes were assessed in this study using both quality indices and information indices, along with visual inspection. The normalized difference vegetation index, normalized difference water index, and morphological building index, which are widely used in applications related to land cover classification, the extraction of vegetation areas, buildings, and water bodies, were employed in this work to evaluate the performance of different pansharpening methods in terms of information presentation ability. The experimental results show that the Haze- and Ratio-based, adaptive Gram-Schmidt, Generalized Laplacian pyramids (GLP) methods using enhanced spectral distortion minimal model and enhanced context-based decision model methods are good choices for producing fused WV-2 images used for image interpretation and the extraction of urban buildings. The two GLP-based methods are better choices than the other methods, if the fused images will be used for applications related to vegetation and water-bodies.

  2. Antimicrobial activity of honey from the stingless bee Trigona carbonaria determined by agar diffusion, agar dilution, broth microdilution and time-kill methodology.

    PubMed

    Boorn, K L; Khor, Y-Y; Sweetman, E; Tan, F; Heard, T A; Hammer, K A

    2010-05-01

    The aim of this study was to determine the spectrum of antimicrobial activity of 11 samples of stingless bee honey compared to medicinal, table and artificial honeys. Activity was assessed by agar diffusion, agar dilution, broth microdilution and time-kill viability assays. By agar dilution, minimum inhibitory concentration (MIC) ranges were 4% to >10% (w/v) for Gram-positive bacteria, 6% to >16% (w/v) for Gram-negative bacteria and 6% to >10% (w/v) for Candida spp. By broth microdilution, all organisms with the exception of Candida albicans and Candida glabrata were inhibited at w/v). Geometric MIC (w/v) means for stingless bee honeys ranged from 7.1% to 16.0% and were 11.7% for medicinal honey and 26.5% for table honey. Treatment of organisms with 20% (w/v) stingless bee honey for 60 min resulted in decreases of 1-3 log for Staphylococcus aureus, >3 log for Pseudomonas aeruginosa and <1 log for C. albicans. Similar treatment with each control honey resulted in decreases of <1 log for all organisms. Stingless bee honey has broad-spectrum antibacterial activity although activity against Candida was limited. Stingless bee honey samples varied in activity and the basis for this remains to be determined. Stingless bee honey had similar activity to medicinal honey and may therefore have a role as a medicinal agent.

  3. Assessment of Pansharpening Methods Applied to WorldView-2 Imagery Fusion

    PubMed Central

    Li, Hui; Jing, Linhai; Tang, Yunwei

    2017-01-01

    Since WorldView-2 (WV-2) images are widely used in various fields, there is a high demand for the use of high-quality pansharpened WV-2 images for different application purposes. With respect to the novelty of the WV-2 multispectral (MS) and panchromatic (PAN) bands, the performances of eight state-of-art pan-sharpening methods for WV-2 imagery including six datasets from three WV-2 scenes were assessed in this study using both quality indices and information indices, along with visual inspection. The normalized difference vegetation index, normalized difference water index, and morphological building index, which are widely used in applications related to land cover classification, the extraction of vegetation areas, buildings, and water bodies, were employed in this work to evaluate the performance of different pansharpening methods in terms of information presentation ability. The experimental results show that the Haze- and Ratio-based, adaptive Gram-Schmidt, Generalized Laplacian pyramids (GLP) methods using enhanced spectral distortion minimal model and enhanced context-based decision model methods are good choices for producing fused WV-2 images used for image interpretation and the extraction of urban buildings. The two GLP-based methods are better choices than the other methods, if the fused images will be used for applications related to vegetation and water-bodies. PMID:28067770

  4. Megakaryocytes compensate for Kit insufficiency in murine arthritis.

    PubMed

    Cunin, Pierre; Penke, Loka R; Thon, Jonathan N; Monach, Paul A; Jones, Tatiana; Chang, Margaret H; Chen, Mary M; Melki, Imene; Lacroix, Steve; Iwakura, Yoichiro; Ware, Jerry; Gurish, Michael F; Italiano, Joseph E; Boilard, Eric; Nigrovic, Peter A

    2017-05-01

    The growth factor receptor Kit is involved in hematopoietic and nonhematopoietic development. Mice bearing Kit defects lack mast cells; however, strains bearing different Kit alleles exhibit diverse phenotypes. Herein, we investigated factors underlying differential sensitivity to IgG-mediated arthritis in 2 mast cell-deficient murine lines: KitWsh/Wsh, which develops robust arthritis, and KitW/Wv, which does not. Reciprocal bone marrow transplantation between KitW/Wv and KitWsh/Wsh mice revealed that arthritis resistance reflects a hematopoietic defect in addition to mast cell deficiency. In KitW/Wv mice, restoration of susceptibility to IgG-mediated arthritis was neutrophil independent but required IL-1 and the platelet/megakaryocyte markers NF-E2 and glycoprotein VI. In KitW/Wv mice, platelets were present in numbers similar to those in WT animals and functionally intact, and transfer of WT platelets did not restore arthritis susceptibility. These data implicated a platelet-independent role for the megakaryocyte, a Kit-dependent lineage that is selectively deficient in KitW/Wv mice. Megakaryocytes secreted IL-1 directly and as a component of circulating microparticles, which activated synovial fibroblasts in an IL-1-dependent manner. Transfer of WT but not IL-1-deficient megakaryocytes restored arthritis susceptibility to KitW/Wv mice. These findings identify functional redundancy among Kit-dependent hematopoietic lineages and establish an unanticipated capacity of megakaryocytes to mediate IL-1-driven systemic inflammatory disease.

  5. Characterization of biofilm formation by Salmonella enterica at the air-liquid interface in aquatic environments.

    PubMed

    Medrano-Félix, José Andrés; Chaidez, Cristóbal; Mena, Kristina D; Soto-Galindo, María Del Socorro; Castro-Del Campo, Nohelia

    2018-03-15

    Survival of bacterial pathogens in different environments is due, in part, to their ability to form biofilms. Four wild-type Salmonella enterica strains, two Oranienburg and two Saintpaul isolated from river water and animal feces, were tested for biofilm formation at the air-liquid interface under stressful conditions (pH and salinity treatments such as pH 3, NaCl 4.5 w/v; pH 7, NaCl 4.5 w/v; pH 10, NaCl 4.5 w/v; pH 3, Nacl 0.5 w/v; pH 7, NaCl 0.5 w/v; and pH 10, NaCl 0.5 w/v); Salmonella Typhimurium DT104 was used as a control strain. Salmonella Oranienburg and Saintpaul from feces were moderately hydrophobic and motile, while S. Saintpaul from water and the control strain S. Typhimurium showed high hydrophobicity, which helped them form more resistant biofilms than S. Oranienburg. Under stressful conditions, all strains experienced difficulties in forming biofilms. Salmonella Saintpaul and Typhimurium expressed the red dry and rough (RDAR) morphotype and were able to form biofilm at air-liquid interface, contrarily to Oranienburg that showed incomplete rough morphology. This study contributes to the knowledge of biofilm formation as a survival strategy for Salmonella in aquatic environments.

  6. Development of double emulsion nanoparticles for the encapsulation of bovine serum albumin.

    PubMed

    Martinez, Nelida Y; Andrade, Patricia F; Durán, Nelson; Cavalitto, Sebastian

    2017-10-01

    In the present work, a double emulsion was developed for the encapsulation of Bovine Serum Albumin (BSA) as a model protein for the future encapsulation of viral proteins. The first emulsion polydispersity index (PDI) was studied with increasing concentrations of poly (ε-caprolactone) (PCL) as stabilizer (from 16% w/v to 5% w/v) and polyvinyl alcohol (PVA) as the surfactant in the second emulsion at 1.5% w/v. Results suggest that at decreasing concentrations of PCL the PDI of the emulsion also decrease, indicating that viscosity of the emulsion is crucial in the homogeneity of the resultant size distribution of the nanoparticles. When PVA concentration in the second emulsion was increased from 1.5% w/v to 2.5% w/v the PDI also increased. To study the relationship between the structure of the surfactant in the second emulsion and the resultant BSA encapsulation, emulsions were prepared with Pluronic F68 and PVA both at 1.5% w/v and PCL in the first emulsion at 5% w/v. Results indicated that Pluronic F68 was a better stabilizer because at the same experimental conditions encapsulation of BSA was 1.5 higher than PVA. FTIR studies confirmed the presence of BSA in the nanoparticles. SEM and TEM microscopies showed a size distribution of 300nm-500nm size of nanoparticles. Circular dichroism studies demonstrated that the secondary structure of the protein was conserved after the encapsulation into the nanoparticles. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. N2O and CH4 emissions from N-fertilized rice paddy soil can be mitigated by wood vinegar application at an appropriate rate

    NASA Astrophysics Data System (ADS)

    Sun, Haijun; Feng, Yanfang; Ji, Yang; Shi, Weiming; Yang, Linzhang; Xing, Baoshan

    2018-07-01

    To understand the impacts of wood vinegar (WV), a by-product of biochar production, on N2O and CH4 emissions and their total global warming potential (GWPt) from N-fertilized rice paddy soil, a soil column experiment was conducted using three treatments: 240 kg urea-N ha-1 accompanied with 0, 5, and 10 t WV ha-1, respectively. Results showed that N2O and CH4 emission flux patterns were dominated by water regime of rice growth cycle, which was independent with WV application. The total N2O, CH4 emission loads and GWPt over rice season of three N received treatments were 6.41-8.85 kg ha-1, 127.7-405.0 kg ha-1, and 5.24-12.03 t CO2-e ha-1, respectively. Rice seasonal N2O and CH4 emissions were synchronously mitigated by 22.4% and 36.4%, respectively, when WV was applied at 5 t ha-1. Consequently, 5 t ha-1 WV treatment reduced 31.5% of GWPt compared with the urea treatment. In addition, 10 t ha-1 WV treatment exerted a more positive effect on suppressing N2O with 27.6% reduction. However, it increased GWPt by 57.2% because its CH4 emission load was increased by 101.8%. In conclusion, WV amendment applied at an appropriate rate (5 t ha-1) or combination with other CH4 control technologies were suggested to reduce both N2O and CH4 emissions and thereby the GWPt in N-fertilized rice paddy soil.

  8. Combining biochar, zeolite and wood vinegar for composting of pig manure: The effect on greenhouse gas emission and nitrogen conservation.

    PubMed

    Wang, Quan; Awasthi, Mukesh Kumar; Ren, Xiuna; Zhao, Junchao; Li, Ronghua; Wang, Zhen; Wang, Meijing; Chen, Hongyu; Zhang, Zengqiang

    2018-04-01

    The effect of enhancing wood vinegar (WV) with a mixture of biochar (B) and zeolite (Z) to compost pig manure (PM) in a 130 L reactor was evaluated to determine the levels of greenhouse gas (GHG) and ammonia emissions. Six treatments were prepared in a 2:1 ratio of PM mixed with wheat straw (WS; dry weight basis): PM + WS (control), PM + WS + 10%B, PM + WS + 10%B + 10%Z, and PM + WS with 0.5%, 1.0% and 2.0%WV combined with 10%B + 10%Z. These were composted for 50 days, and the results indicated that the combined use of B, Z, and WV could shorten the thermophilic phase and improve the maturity of compost compared to the control treatment. In addition, WV mixed with B and Z could reduce ammonia loss by 64.45-74.32% and decrease CO 2 , CH 4 , and N 2 O emissions by 33.90-46.98%, 50.39-61.15%, and 79.51-81.10%, respectively. Furthermore, compared to treatments in which B and B + Z were added, adding WV was more efficient to reduce the nitrogen and carbon loss, and the 10%B + 10%Z + 2%WV treatment presented the lowest loss of carbon (9.16%) and nitrogen (0.75%). Based on the maturity indexes used, nitrogen conservation, and efficiency of GHG emissions reduction, the treatment 10%B + 10%Z + 2%WV is suggested for efficient PM composting. Copyright © 2018 Elsevier Ltd. All rights reserved.

  9. Flavobacterium kingsejongi sp. nov., a carotenoid-producing species isolated from Antarctic penguin faeces.

    PubMed

    Choi, Jun Young; Kim, Jin Ho; Lee, Pyung Cheon

    2018-03-01

    Taxonomic studies were carried out on a carotenoid-producing strain, designated WV39 T , isolated from the faeces of Antarctic penguins. Cells of strain WV39 T were Gram-stain-negative, strictly aerobic, yellow and rod-shaped. 16S rRNA gene sequence analysis revealed that strain WV39 T was closely related to Flavobacterium qiangtangense JCM 19739 T (96.3 % similarity), Flavobacterium noncentrifugens NBRC 108844 T (95.5 %) and Flavobacterium aquatile LMG 4008 T (94.9 %). The predominant cellular fatty acids were iso-C15 : 0, iso-C15 : 0 3-OH and summed feature 3 (comprising iso-C15 : 0 2-OH and/or C16 : 1ω7c). Menaquinone-6 was the sole quinone identified, and the major pigment was zeaxanthin. The major polar lipid was phosphatidylethanolamine. DNA-DNA relatedness of strain WV39 T with respect to its closest phylogenetic neighbours was 41.8 % for F. qiangtangense JCM 19739 T , 25.5 % for F. aquatile LMG 4008 T and 25.2 % for F. noncentrifugens NBRC 108844 T . The DNA G+C content of strain WV39 T was 39.8 mol%. Based on the phenotypic, chemotaxonomic and phylogenetic data, strain WV39 T is concluded to represent a novel species of the genus Flavobacterium, for which the name Flavobacteriumkingsejongi sp. nov. is proposed. The type strain is WV39 T (=KCTC 42908 T =CECT 9085 T ).

  10. Stratospheric water vapor and ozone evaluation in reanalyses as part of the SPARC Reanalysis Intercomparison Project (S-RIP)

    NASA Astrophysics Data System (ADS)

    Davis, S. M.; Hegglin, M. I.; Fujiwara, M.; Manney, G. L.; Dragani, R.; Nash, E.; Tegtmeier, S.; Kobayashi, C.; Harada, Y.; Long, C. S.; Wargan, K.; Rosenlof, K. H.

    2017-12-01

    Reanalyses are widely used to understand atmospheric processes and past variability, and are often used to stand in as "observations" for comparisons with climate model output. Because of the central role of water vapor (WV) and ozone (O3) in climate change, it is important to understand how accurately and consistently these species are represented in existing global reanalyses. Here we present the results of WV and O3 intercomparisons that have been performed as part of the SPARC (Stratosphere-troposphere Processes and their Role in Climate) Reanalysis Intercomparison Project (S-RIP). The comparisons cover a range of timescales and evaluate both inter-reanalysis and observation-reanalysis differences. The assimilation of total column ozone (TCO) observations in newer reanalyses results in realistic representations of TCO in reanalyses except when data coverage is lacking, such as during polar night. The vertical distribution of ozone is also relatively well represented in the stratosphere in reanalyses, particularly given the relatively weak constraints on ozone vertical structure provided by most assimilated observations and the simplistic representations of ozone photochemical processes in most of the reanalysis forecast models. For times when vertically resolved observations are not assimilated, biases in the vertical distribution of ozone are found in the upper troposphere and lower stratosphere in all reanalyses. In contrast to O3, reanalysis stratospheric WV fields are not directly constrained by assimilated data. Observations of atmospheric humidity are typically used only in the troposphere, below a specified vertical level at or near the tropopause. The fidelity of reanalysis stratospheric WV products is therefore dependent on the reanalyses' representation of processes that influence stratospheric WV, such as tropical tropopause layer temperatures and methane oxidation. The lack of assimilated observations and known deficiencies in the representation of

  11. Production of a bioemulsifier with potential application in the food industry.

    PubMed

    Campos, Jenyffer M; Stamford, Tânia L M; Sarubbo, Leonie A

    2014-03-01

    Biosurfactants are of considerable interest due to their biodegradability, low degree of toxicity, and diverse applications. However, the high production costs involved in the acquisition of biosurfactants underscore the need for optimization of the production process to enable viable application on an industrial scale. The aims of the present study were to select a species of Candida that produces a biosurfactant with the greatest emulsifying potential and to investigate the influence of components of the production medium and cultivation conditions. Candida utilis achieved the lowest surface tension (35.53 mN/m), best emulsification index (73%), and highest yield (12.52 g/l) in a medium containing waste canola frying oil as the carbon source and ammonium nitrate as the nitrogen source. The best combination of medium components and cultivation conditions was 6% (w/v) glucose, 6% (w/v) waste canola frying oil, 0.2% (w/v) ammonium nitrate, 0.3% (w/v) yeast extract, 150 rpm, 1% inoculum (w/v), and 88 h of fermentation. The greatest biosurfactant production and the lowest surface tension were achieved in the first 24 h of production, and the maximum biomass production was recorded at 72 h. The biosurfactant produced from C. utilis under the conditions investigated in the present study has a potential to be a bioemulsifier for application in the food industry.

  12. Quantifying Libya-4 Surface Reflectance Heterogeneity With WorldView-1, 2 and EO-1 Hyperion

    NASA Technical Reports Server (NTRS)

    Neigh, Christopher S. R.; McCorkel, Joel; Middleton, Elizabeth M.

    2015-01-01

    The land surface imaging (LSI) virtual constellation approach promotes the concept of increasing Earth observations from multiple but disparate satellites. We evaluated this through spectral and spatial domains, by comparing surface reflectance from 30-m Hyperion and 2-m resolution WorldView-2 (WV-2) data in the Libya-4 pseudoinvariant calibration site. We convolved and resampled Hyperion to WV-2 bands using both cubic convolution and nearest neighbor (NN) interpolation. Additionally, WV-2 and WV-1 same-date imagery were processed as a cross-track stereo pair to generate a digital terrain model to evaluate the effects from large (>70 m) linear dunes. Agreement was moderate to low on dune peaks between WV-2 and Hyperion (R2 <; 0.4) but higher in areas of lower elevation and slope (R2 > 0.6). Our results provide a satellite sensor intercomparison protocol for an LSI virtual constellation at high spatial resolution, which should start with geolocation of pixels, followed by NN interpolation to avoid tall dunes that enhance surface reflectance differences across this internationally utilized site.

  13. Formulation development of smart gel periodontal drug delivery system for local delivery of chemotherapeutic agents with application of experimental design.

    PubMed

    Dabhi, Mahesh R; Nagori, Stavan A; Gohel, Mukesh C; Parikh, Rajesh K; Sheth, Navin R

    2010-01-01

    Smart gel periodontal drug delivery systems (SGPDDS) containing gellan gum (0.1-0.8% w/v), lutrol F127 (14, 16, and 18% w/v), and ornidazole (1% w/v) were designed for the treatment of periodontal diseases. Each formulation was characterized in terms of in vitro gelling capacity, viscosity, rheology, content uniformity, in vitro drug release, and syringeability. In vitro gelation time and the nature of the gel formed in simulated saliva for prepared formulations showed polymeric concentration dependency. Drug release data from all formulations was fitted to different kinetic models and the Korsemeyer-Peppas model was the best fit model. Drug release was significantly decreased as the concentration of each polymer component was increased. Increasing the concentration of each polymeric component significantly increased viscosity, syringeability, and time for 50%, 70%, and 90% drug release. In conclusion, the formulations described offer a wide range of physical and drug release characteristics. The formulation containing 0.8% w/v of gellan gum and 16% w/v of lutrol F127 exhibited superior physical characteristics.

  14. Blistering behavior and deuterium retention in tungsten vanadium alloys exposed to deuterium plasma in the linear plasma device STEP

    NASA Astrophysics Data System (ADS)

    Wang, Jun; Cheng, Long; Yuan, Yue; Qin, Shao-Yang; Arshad, Kameel; Guo, Wang-Guo; Wang, Zheng; Zhou, Zhang-Jian; Lu, Guang-Hong

    2018-03-01

    The behavior of tungsten-vanadium (W-V) alloys fabricated by powder metallurgy as a plasma facing material has been studied. W-V alloys with different vanadium concentrations (5 and 10 wt %) manufactured by hot pressing (HP) were exposed to deuterium plasma (flux ∼4.6 × 1021 m-2s-1, fluence ∼5.6 × 1025 m-2, ion energy ∼60 eV, target temperature ∼450 K) in the linear plasma device STEP at Beihang University. Three typical grains are observed on HP sintered W-V alloys and exhibit a significant effect on its performance under deuterium plasma irradiation. Surface blistering only occurs at W-enriched grains and is significantly mitigated in W-V alloys, especially in W-10 V, blistering is completely suppressed. On the other hand, deuterium retention dramatically increases in the W-V alloys due to vanadium addition. The deuterium retention in W-5 wt. % V is about 6.2 times more than that in rolled pure W, and this factor further increases to 6.9 when the V concentration rises to 10 wt %. We ascribe these phenomena to the changes of microstructures and components caused by vanadium addition.

  15. Genome-scale metabolic modeling of Mucor circinelloides and comparative analysis with other oleaginous species.

    PubMed

    Vongsangnak, Wanwipa; Klanchui, Amornpan; Tawornsamretkit, Iyarest; Tatiyaborwornchai, Witthawin; Laoteng, Kobkul; Meechai, Asawin

    2016-06-01

    We present a novel genome-scale metabolic model iWV1213 of Mucor circinelloides, which is an oleaginous fungus for industrial applications. The model contains 1213 genes, 1413 metabolites and 1326 metabolic reactions across different compartments. We demonstrate that iWV1213 is able to accurately predict the growth rates of M. circinelloides on various nutrient sources and culture conditions using Flux Balance Analysis and Phenotypic Phase Plane analysis. Comparative analysis of three oleaginous genome-scale models, including M. circinelloides (iWV1213), Mortierella alpina (iCY1106) and Yarrowia lipolytica (iYL619_PCP) revealed that iWV1213 possesses a higher number of genes involved in carbohydrate, amino acid, and lipid metabolisms that might contribute to its versatility in nutrient utilization. Moreover, the identification of unique and common active reactions among the Zygomycetes oleaginous models using Flux Variability Analysis unveiled a set of gene/enzyme candidates as metabolic engineering targets for cellular improvement. Thus, iWV1213 offers a powerful metabolic engineering tool for multi-level omics analysis, enabling strain optimization as a cell factory platform of lipid-based production. Copyright © 2016 Elsevier B.V. All rights reserved.

  16. Follicle Depletion Provides a Permissive Environment for Ovarian Carcinogenesis

    PubMed Central

    Wang, Ying; Cai, Kathy Qi; Smith, Elizabeth R.; Yeasky, Toni M.; Moore, Robert; Ganjei-Azar, Parvin; Klein-Szanto, Andres J.; Godwin, Andrew K.; Hamilton, Thomas C.

    2016-01-01

    We modeled the etiology of postmenopausal biology on ovarian cancer risk using germ cell-deficient white-spotting variant (Wv) mice, incorporating oncogenic mutations. Ovarian cancer incidence is highest in peri- and postmenopausal women, and epidemiological studies have established the impact of reproductive factors on ovarian cancer risk. Menopause as a result of ovarian follicle depletion is thought to contribute to higher cancer risk. As a consequence of follicle depletion, female Wv mice develop ovarian tubular adenomas, a benign epithelial tumor corresponding to surface epithelial invaginations and papillomatosis frequently found in postmenopausal human ovaries. Lineage tracing using MISR2-Cre indicated that the tubular adenomas that developed in Wv mice were largely derived from the MISR2 lineage, which marked only a fraction of ovarian surface and oviduct epithelial cells in wild-type tissues. Deletion of p27, either heterozygous or homozygous, was able to convert the benign tubular adenomas into more proliferative tumors. Restricted deletion of p53 in Wv/Wv mice by either intrabursal injection of adenoviral Cre or inclusion of the MISR2-Cre transgene also resulted in augmented tumor growth. This finding suggests that follicle depletion provides a permissive ovarian environment for oncogenic transformation of epithelial cells, presenting a mechanism for the increased ovarian cancer risk in postmenopausal women. PMID:27354067

  17. Second-generation ethanol production from elephant grass at high total solids.

    PubMed

    Menegol, Daiane; Fontana, Roselei Claudete; Dillon, Aldo José Pinheiro; Camassola, Marli

    2016-07-01

    The enzymatic hydrolysis of Pennisetum purpureum (elephant grass) was evaluated at high total solid levels (from 4% to 20% (w/v)) in a concomitant ball milling treatment in a rotating hydrolysis reactor (RHR). The greatest glucose yield was 20.17% when 4% (w/v) untreated biomass was employed. When sugars obtained from enzymatic hydrolysis were submitted to fermentation with Saccharomyces cerevisiae, the greatest ethanol yield was 22.61% when 4% (w/v) untreated biomass was employed; however, the highest glucose concentration (12.47g/L) was obtaining using 20% (w/v) solids and highest ethanol concentration (6.1g/L) was obtained using 16% (w/v) solids. When elephant grass was hydrolyzed in the rotating hydrolysis reactor, ethanol production was about double that was produced when the biomass was hydrolyzed in a static reactor (SR). These data indicate that it is possible to produce ethanol from elephant grass when milling treatment and enzymatic hydrolysis are performed at the same time. Copyright © 2016. Published by Elsevier Ltd.

  18. Leaf age affects the responses of foliar injury and gas exchange to tropospheric ozone in Prunus serotina seedlings.

    PubMed

    Zhang, Jianwei; Schaub, Marcus; Ferdinand, Jonathan A; Skelly, John M; Steiner, Kim C; Savage, James E

    2010-08-01

    We investigated the effect of leaf age on the response of net photosynthesis (A), stomatal conductance (g(wv)), foliar injury, and leaf nitrogen concentration (N(L)) to tropospheric ozone (O(3)) on Prunus serotina seedlings grown in open-plots (AA) and open-top chambers, supplied with either carbon-filtered or non-filtered air. We found significant variation in A, g(wv), foliar injury, and N(L) (P < 0.05) among O(3) treatments. Seedlings in AA showed the highest A and g(wv) due to relatively low vapor pressure deficit (VPD). Older leaves showed significantly lower A, g(wv), N(L), and higher foliar injury (P < 0.001) than younger leaves. Leaf age affected the response of A, g(wv), and foliar injury to O(3). Both VPD and N(L) had a strong influence on leaf gas exchange. Foliar O(3)-induced injury appeared when cumulative O(3) uptake reached 8-12 mmol m(-2), depending on soil water availability. The mechanistic assessment of O(3)-induced injury is a valuable approach for a biologically relevant O(3) risk assessment for forest trees. Published by Elsevier Ltd.

  19. Sugars of the unfermented sap and the wine from the oil palm, Elaeis guinensis, tree.

    PubMed

    Eze, M O; Ogan, U

    1988-01-01

    The sugar composition of the unfermented sap from oil palm (Elaeis guinensis) trees growing in the plantations of the Nigerian Institute for Oil Palm Research, Benin City, has been determined. While sucrose concentration ranges from 9.59 to 10.59% (w/v) in the pure unfermented sap, that of either glucose or fructose is much less than 1% (w/v) (0.13-0.73% w/v). Raffinose occurs in traces only (0.13-0.35 w/v). These results were derived from our improved methods which eliminate completely, or reduce to a bare minimum, fermentation of the sap during collection. The variation with time of storage of the individual sugars in the sap during fermentation to form palm wine reveals that, as sucrose steadily decreases, fructose reaches a peak at 1.51% (w/v) at the 9th hour, and thereafter declines, while glucose and raffinose remain continuously low; all sugars disappear beyond the 33rd hour. Concomittantly, pH decreases from pH 6.60 at zero time and stabilizes at pH 3.30 after 48 h, while titrable acidity increases continuously up until the 96th hour. These changes account for the variations in the quality of palm wine during storages.

  20. Production, Purification, and Characterization of Polygalacturonase from Mucor circinelloides ITCC 6025

    PubMed Central

    Thakur, Akhilesh; Pahwa, Roma; Singh, Smarika; Gupta, Reena

    2010-01-01

    Mucor circinelloides produced an extracellular polygalacturonase enzyme, the production of which was enhanced when various production parameters were optimized. Maximum polygalacturonase (PGase) activity was obtained in 48 h at 30°C and pH 4.0 with pectin methyl ester (1% w/v) as carbon source and a combination of casein hydrolysate (0.1% w/v) and yeast extract (0.1% w/v) as nitrogen source. The enzyme was purified to homogeneity (13.3-fold) by Sephacryl S-100 gel-filtration chromatography. Its molecular weight was 66 kDa on SDS-PAGE. The enzyme was found to have K m and V max values of 2.2 mM and 4.81 IU/ml at 0.1% to 0.5% (w/v) concentration of the substrate. The addition of phenolic acids (0.05 mM), metal ions such as Mn+2, Co+2, Mg+2, Fe+3, Al+3, Hg+2, and Cu+2, and thiols had inhibitory effect on the enzyme. The enzyme showed maximum activity in the presence of polygalacturonic acid (0.1% w/v) at pH 5.5 and 42°C. PMID:21048861

  1. Special diatomite solves fiberglass particles filtration problem

    SciTech Connect

    Not Available

    1979-07-01

    Johns-Manville Corp. has developed a water treatment system which is based on the principle of zero-discharge of process water and which uses an alum-coated Celite diatomaceous earth filter for removing particles of carbon black and abrasive glass, tramp dirt, and oils and grease out of waste water from its fiberglass plants at Parkersburg, W. Va., and elsewhere. The resulting water is essentially free of suspended solids larger than 0.5j at Vertical Bar3; 5 mg/l. concentration, even when the solids concentration in the filter feed water ranges from 50 to 1000 mg/l. The system's core is the alum coating, which ismore » obtained by reacting the diatomite with aluminum sulfate and soda ash. Because it has a highly positive electrical charge, the coating attracts the negatively charged carbon particles and attaches them to the diatomite surface to be filtered out. Filtration cycles vary from 8 to 24 hr depending on the raw water and filter grade used; the terminal pressure is about 60 psig. At cycles' end, the filter cake is up to 2.5 in. thick; this is disposed of in sanitary landfills.« less

  2. 78 FR 38256 - Approval and Promulgation of Air Quality Implementation Plans; Ohio; Redesignation of the Ohio...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-26

    ...EPA is issuing a supplement to its proposed approval of Ohio's request to redesignate the Ohio portion of the Parkersburg-Marietta, West Virginia-Ohio, area to attainment for the 1997 annual National Ambient Air Quality Standards (NAAQS or standard) for fine particulate matter (PM2.5). This supplemental proposal revises and expands the basis for proposing approval of the state's request, in light of developments since EPA issued its initial proposal on November 30, 2012. This supplemental proposal addresses the effects of a January 4, 2013, decision of the United States Court of Appeals for the District of Columbia (D.C. Circuit or Court) to remand to EPA two final rules implementing the 1997 PM2.5 standard. In this supplemental proposal, EPA is also proposing to approve a supplement to the emission inventories previously submitted by Ohio. EPA is proposing that the inventories for ammonia and volatile organic compounds (VOC), in conjunction with the inventories for nitrogen oxides (NOX), direct PM2.5, and sulfur dioxide (SO2) that EPA previously proposed to approve, meet the comprehensive emissions inventory requirements of the Clean Air Act (CAA or Act). EPA is seeking comment only on the issues raised in its supplemental proposal, and is not re-opening for comment other issues raised in its prior proposal.

  3. Color stabilization of porcine hemoglobin during spray-drying and powder storage by combining chelating and reducing agents.

    PubMed

    Salvador, P; Toldrà, M; Parés, D; Carretero, C; Saguer, E

    2009-10-01

    This work focuses on the effects of adding a chelating agent - such as nicotinic acid (NA, 2% w/v) or nicotinamide (Nam, 2.5% w/v) - along with glucose as a reducing agent (G, 10% w/v) to fresh porcine hemoglobin in order to stabilize its red color during spray-drying and powder storage at room temperature. Correlations between the CIELAB color parameters and the relative percentages of the different hemoglobin derivatives (liganded and deliganded ferrohemoglobin, and methemoglobin) were analyzed. The results indicate that, although little effects could be observed for any of the combined treatments on fresh hemoglobin, they were effective against pigment autoxidation during dehydration and subsequent storage. From the results, it can also be concluded that glucose was the main contributor to the color stabilization of the hemoglobin powder, probably due to its high water retention capacity.

  4. DOE Eastern Gas Shales Project: Dunkirk study. Quarterly report of technical progress, July, August, September 1979

    SciTech Connect

    Harper, J.A.; Abel, K.D.; Piotrowski, R.G.

    Ten cross sections were completed and drafted, and blueline copies were sent to DOE, Morgantown, WV, for review. These cross sections were used as the basis with which all other logs in the study area were correlated. The data has been encoded from 228 logs that were used. Two isopach, 2 structure contour, and 3 lithofacies maps have been completed and are awaiting drafting. A production and show map has been drafted and blueline copies were sent to DOE, Morgantown, WV, for review. The schedule of work was delayed due to the state budget problems the need to correct workmore » previously completed and sent to DOE, Morgantown, WV, and lack of a reproduction contract.« less

  5. Developing a Dissemination Model to Improve Intervention Reach among West Virginia Youth Smokers

    PubMed Central

    Horn, Kimberly; Jarrett, Traci; Anesetti-Rothermel, Andrew; O’Hara Tompkins, Nancy; Dino, Geri

    2014-01-01

    The not-on-tobacco program is an evidence-based teen smoking cessation program adopted by the American Lung Association (ALA). Although widely disseminated nationally via ALA Master Trainers, in recent years, adoption and implementation of the N-O-T program in West Virginia (WV) has slowed. WV, unfortunately, has one of the highest smoking rates in the US. Although it is a goal of public health science, dissemination of evidence-based interventions is woefully understudied. The present manuscript reviews a theoretical model of dissemination of the not-on-tobacco program in WV. Based on social marketing, diffusion of innovations, and social cognitive theories, the nine-phase model incorporates elements of infrastructure development, accountability, training, delivery, incentives, and communication. The model components as well as preliminary lessons learned from initial implementation are discussed. PMID:25136547

  6. Bioleaching of rare earth and radioactive elements from red mud using Penicillium tricolor RM-10.

    PubMed

    Qu, Yang; Lian, Bin

    2013-05-01

    The aim of this work is to investigate biological leaching of rare earth elements (REEs) and radioactive elements from red mud, and to evaluate the radioactivity of the bioleached red mud used for construction materials. A filamentous, acid-producing fungi named RM-10, identified as Penicillium tricolor, is isolated from red mud. In our bioleaching experiments by using RM-10, a total concentration of 2% (w/v) red mud under one-step bioleaching process was generally found to give the maximum leaching ratios of the REEs and radioactive elements. However, the highest extraction yields are achieved under two-step bioleaching process at 10% (w/v) pulp density. At pulp densities of 2% and 5% (w/v), red mud processed under both one- and two-step bioleaching can meet the radioactivity regulations in China. Copyright © 2013 Elsevier Ltd. All rights reserved.

  7. Wake modeling in complex terrain using a hybrid Eulerian-Lagrangian Split Solver

    NASA Astrophysics Data System (ADS)

    Fuchs, Franz G.; Rasheed, Adil; Tabib, Mandar; Fonn, Eivind

    2016-09-01

    Wake vortices (WVs) generated by aircraft are a source of risk to the following aircraft. The probability of WV related accidents increases in the vicinity of airport runways due to the shorter time of recovery after a WV encounter. Hence, solutions that can reduce the risk of WV encounters are needed to ensure increased flight safety. In this work we propose an interesting approach to model such wake vortices in real time using a hybrid Eulerian- Lagrangian approach. We derive an appropriate mathematical model, and show a comparison of the different types of solvers. We will conclude with a real life application of the methodology by simulating how wake vortices left behind by an aircraft at the Vffirnes airport in Norway get transported and decay under the influence of a background wind and turbulence field. Although the work demonstrates the application in an aviation context the same approach can be used in a wind energy context.

  8. Utilization of methanol in crude glycerol to assist lipid production in non-sterilized fermentation from Trichosporon oleaginosus.

    PubMed

    Chen, Jiaxin; Zhang, Xiaolei; Tyagi, Rajeshwar Dayal; Drogui, Patrick

    2018-04-01

    In this work, methanol in crude glycerol solution was used to assist the lipid production with oleaginous yeast Trichosporon oleaginosus cultivated under non-sterilized conditions. The investigated methanol concentration was 0%, 1.4%, 2.2%, 3.3% and 4.4% (w/v). The results showed that methanol played a significant role in the non-sterilized fermentation for lipid production. The optimal methanol concentration was around 1.4% (w/v) in which the growth of T. oleaginosus was promoted and overcame that of the contaminants. The non-sterilized fed-batch fermentation with initial methanol concentration of 1.4% (w/v) was then performed and high biomass production (43.39 g/L) and lipid production (20.42 g/L) were achieved. Copyright © 2018 Elsevier Ltd. All rights reserved.

  9. Workplace violence and occupational stress in healthcare workers: a chicken-and-egg situation-results of a 6-year follow-up study.

    PubMed

    Magnavita, Nicola

    2014-09-01

    Violence at work (WV) is an important occupational hazard for health care workers (HCWs). A number of surveys addressing the causes and effects of WV have shown that it is associated with work-related stress. However, it is not clear what direction this relationship takes, that is, whether job strain facilitates aggression against HCWs or WV is the cause of job strain. From 2003 to 2009, HCWs from a public health care unit were asked to self-assess their level of work-related stress and to report aggression that occurred in the 12-month period preceding their routine medical examination. In 2009, physical and mental health and job satisfaction were also assessed. A total of 698 out of 723 HCWs (96.5%) completed the study. Job strain and lack of social support were predictors of the occurrence of nonphysical aggression during the ensuing year. HCWs who experienced WV reported high strain and low support at work in the following year. The experience of nonphysical violence and a prolonged state of strain and social isolation were significant predictors of psychological problems and bad health at follow-up. The relationship between work-related distress and WV is bidirectional. The monitoring of workers through questionnaires distributed before their periodic examination is a simple and effective way of studying WV and monitoring distress. The findings of the present study may facilitate the subsequent design of participatory intervention for the prevention of violence in healthcare facilities. This should always be accompanied by measures designed to reduce strain and improve social support. © 2014 Sigma Theta Tau International.

  10. Sources of Intermodel Spread in the Lapse Rate and Water Vapor Feedbacks

    SciTech Connect

    Po-Chedley, Stephen; Armour, Kyle C.; Bitz, Cecilia M.

    Sources of intermodel differences in the global lapse rate (LR) and water vapor (WV) feedbacks are assessed using CO 2 forcing simulations from 28 general circulation models. Tropical surface warming leads to significant warming and moistening in the tropical and extratropical upper troposphere, signifying a nonlocal, tropical influence on extratropical radiation and feedbacks. Model spread in the locally defined LR and WV feedbacks is pronounced in the Southern Ocean because of large-scale ocean upwelling, which reduces surface warming and decouples the surface from the tropospheric response. The magnitude of local extratropical feedbacks across models and over time is well characterizedmore » using the ratio of tropical to extratropical surface warming. It is shown that model differences in locally defined LR and WV feedbacks, particularly over the southern extratropics, drive model variability in the global feedbacks. The cross-model correlation between the global LR and WV feedbacks therefore does not arise from their covariation in the tropics, but rather from the pattern of warming exerting a common control on extratropical feedback responses. Because local feedbacks over the Southern Hemisphere are an important contributor to the global feedback, the partitioning of surface warming between the tropics and the southern extratropics is a key determinant of the spread in the global LR and WV feedbacks. It is also shown that model Antarctic sea ice climatology influences sea ice area changes and southern extratropical surface warming. In conclusion, as a result, model discrepancies in climatological Antarctic sea ice area have a significant impact on the intermodel spread of the global LR and WV feedbacks.« less

  11. In vitro and in vivo biological characterization of poly(lactic acid) fiber scaffolds synthesized by air jet spinning.

    PubMed

    Granados-Hernández, Marco Vladimir; Serrano-Bello, Janeth; Montesinos, Juan José; Alvarez-Gayosso, Carlos; Medina-Velázquez, Luis Alberto; Alvarez-Fregoso, Octavio; Alvarez-Perez, Marco Antonio

    2017-11-30

    Poly(lactic acid) (PLA) is one of the most promising renewable and biodegradable polymers for mimic extracellular matrix for tissue engineering applications. In this work, PLA spun membrane scaffold were successfully prepared by air jet spinning technology. Morphology, mechanical properties, in vitro biocompatibility, and in vitro and in vivo degradation of PLA fibrous scaffold were characterized by X-ray diffraction, Fourier Transform Infrared, and scanning electron microscope (SEM). Morphological results assessed by SEM analyses indicated that PLA scaffolds possessed an average fiber diameter of approximately 0.558 ± 0.141 µm for 7% w/v of PLA and approximately 0.647 ± 0.137 µm for 10% w/v. Interestingly, our results showed that the nanofiber size of PLA scaffold allow structural stability after 100 days of in vitro degradation in Ringer solution where the average fiber diameter were of approximately 0.633 ± 0.147 µm for 7% w/v and approximately 0.645 ± 0.140 µm for 10% w/v of PLA. Mechanical properties of PLA fibers scaffold after in vitro degradation showed decrease in terms of flexibility elongation, and less energy was needed to achieve maximal elastic deformation. The fiber size exerts an influence on the biological response of human Bone Marrow Mesenchymal Stromal Cells as confirmed by MTT assay after 9 days of cell culture and the in vivo degradation assay of 7% w/v and 10% w/v of PLA scaffold, did not demonstrate evidence of toxicity with a mild inflammatory respond. In conclusion, airbrushing technology promises to be a viable and attractive alternative technique for producing a biocompatible PLA nanofiber scaffold that could be considered for tissue engineering regeneration. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2017. © 2017 Wiley Periodicals, Inc.

  12. Sources of Intermodel Spread in the Lapse Rate and Water Vapor Feedbacks

    DOE PAGES

    Po-Chedley, Stephen; Armour, Kyle C.; Bitz, Cecilia M.; ...

    2018-03-23

    Sources of intermodel differences in the global lapse rate (LR) and water vapor (WV) feedbacks are assessed using CO 2 forcing simulations from 28 general circulation models. Tropical surface warming leads to significant warming and moistening in the tropical and extratropical upper troposphere, signifying a nonlocal, tropical influence on extratropical radiation and feedbacks. Model spread in the locally defined LR and WV feedbacks is pronounced in the Southern Ocean because of large-scale ocean upwelling, which reduces surface warming and decouples the surface from the tropospheric response. The magnitude of local extratropical feedbacks across models and over time is well characterizedmore » using the ratio of tropical to extratropical surface warming. It is shown that model differences in locally defined LR and WV feedbacks, particularly over the southern extratropics, drive model variability in the global feedbacks. The cross-model correlation between the global LR and WV feedbacks therefore does not arise from their covariation in the tropics, but rather from the pattern of warming exerting a common control on extratropical feedback responses. Because local feedbacks over the Southern Hemisphere are an important contributor to the global feedback, the partitioning of surface warming between the tropics and the southern extratropics is a key determinant of the spread in the global LR and WV feedbacks. It is also shown that model Antarctic sea ice climatology influences sea ice area changes and southern extratropical surface warming. In conclusion, as a result, model discrepancies in climatological Antarctic sea ice area have a significant impact on the intermodel spread of the global LR and WV feedbacks.« less

  13. Solubilization conditions for bovine heart mitochondrial membranes allow selective purification of large quantities of respiratory complexes I, III, and V.

    PubMed

    Shimada, Satoru; Maeda, Shintaro; Hikita, Masahide; Mieda-Higa, Kaoru; Uene, Shigefumi; Nariai, Yukiko; Shinzawa-Itoh, Kyoko

    2018-04-24

    Ascertaining the structure and functions of mitochondrial respiratory chain complexes is essential to understanding the biological mechanisms of energy conversion; therefore, numerous studies have examined these complexes. A fundamental part of that research involves devising a method for purifying samples with good reproducibility; the samples obtained need to be stable and their constituents need to retain the same structure and functions they possess when in mitochondrial membranes. Submitochondrial bovine heart particles were isolated using differential centrifugation to adjust to a membrane concentration of 46.0% (w/v) or 31.5% (w/v) based on weight. After 0.7% (w/v) deoxycholic acid, 0.4% (w/v) decyl maltoside, and 7.2% (w/v) potassium chloride were added to the mitochondrial membranes, those membranes were solubilized. At a membrane concentration of 46%, complex V was selectively solubilized, whereas at a concentration of 31.5% (w/v), complexes I and III were solubilized. Two steps-sucrose density gradient centrifugation and anion-exchange chromatography on a POROS HQ 20 μm column-enabled selective purification of samples that retained their structure and functions. These two steps enabled complexes I, III, and V to be purified in two days with a high yield. Complexes I, III, and V were stabilized with n-decyl-β-D-maltoside. A total of 200 mg-300 mg of those complexes from one bovine heart (1.1 kg muscle) was purified with good reproducibility, and the complexes retained the same functions they possessed while in mitochondrial membranes. Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

  14. Detecting Forests Damaged by Pine Wilt Disease at the Individual Tree Level Using Airborne Laser Data and WORLDVIEW-2/3 Images Over Two Seasons

    NASA Astrophysics Data System (ADS)

    Takenaka, Y.; Katoh, M.; Deng, S.; Cheung, K.

    2017-10-01

    Pine wilt disease is caused by the pine wood nematode (Bursaphelenchus xylophilus) and Japanese pine sawyer (Monochamus alternatus). This study attempted to detect damaged pine trees at different levels using a combination of airborne laser scanning (ALS) data and high-resolution space-borne images. A canopy height model with a resolution of 50 cm derived from the ALS data was used for the delineation of tree crowns using the Individual Tree Detection method. Two pan-sharpened images were established using the ortho-rectified images. Next, we analyzed two kinds of intensity-hue-saturation (IHS) images and 18 remote sensing indices (RSI) derived from the pan-sharpened images. The mean and standard deviation of the 2 IHS images, 18 RSI, and 8 bands of the WV-2 and WV-3 images were extracted for each tree crown and were used to classify tree crowns using a support vector machine classifier. Individual tree crowns were assigned to one of nine classes: bare ground, Larix kaempferi, Cryptomeria japonica, Chamaecyparis obtusa, broadleaved trees, healthy pines, and damaged pines at slight, moderate, and heavy levels. The accuracy of the classifications using the WV-2 images ranged from 76.5 to 99.6 %, with an overall accuracy of 98.5 %. However, the accuracy of the classifications using the WV-3 images ranged from 40.4 to 95.4 %, with an overall accuracy of 72 %, which suggests poorer accuracy compared to those classes derived from the WV-2 images. This is because the WV-3 images were acquired in October 2016 from an area with low sun, at a low altitude.

  15. Removal of Volatile Organics from Humidified Air Streams by Absorption.

    DTIC Science & Technology

    1987-12-01

    Type Comments Activated Carbons: SK-4 nut shell LCL coconut shell WV-B coal base CT coconut shell Specialty Carbons: Graphpac graphitized carbon area...Capacity, g/g Percentage Sorbent ( virgin ) (treated)D Change SK-4 0.114 0.117 +2.6 Carbosieve S-11 0.195 0.180 -7.7 Spherocarb 0.149 0.151 +1.3 CT...and WV-B with respect to their adsorption capacities. CT and SK-4 are both coconut -derived carbons produced by the same manufacturer. Differences

  16. Distinction between serological responses following tick-borne encephalitis virus (TBEV) infection vs vaccination, Sweden 2017.

    PubMed

    Albinsson, Bo; Vene, Sirkka; Rombo, Lars; Blomberg, Jonas; Lundkvist, Åke; Rönnberg, Bengt

    2018-01-01

    Tick-borne encephalitis virus (TBEV) is an important European vaccine-preventable pathogen. Discrimination of vaccine-induced antibodies from those elicited by infection is important. We studied anti-TBEV IgM/IgG responses, including avidity and neutralisation, by multiplex serology in 50 TBEV patients and 50 TBEV vaccinees. Infection induced antibodies reactive to both whole virus (WV) and non-structural protein 1 (NS1) in 48 clinical cases, whereas 47 TBEV vaccinees had WV, but not NS1 antibodies, enabling efficient discrimination of infection/vaccination.

  17. Using Meteosat-10 and GPS ZWD measurements for creating regional water vapor maps.

    NASA Astrophysics Data System (ADS)

    Leontiev, Anton; Reuveni, Yuval

    2017-04-01

    Water vapor (WV) is one of the greenhouse gases, which plays a crucial role in global warming. It's investigation is of great importance for climate and global warming studies. One of the main difficulties of such studies is that WV varies constantly across the lower part of the atmosphere. Currently, most of studies provides WV estimations using only one technique such as tropospheric GPS path delays [Duan et al.] or multi-spectral reflected measurements from different meteorological satellites such as the Meteosat series [Schroedter et al.]. Constructing WV maps using only interpolated GPS zenith wet delay (ZWD) estimations has a main disadvantage - it doesn't take in account clouds which are located outside the integrated GPS paths. Using our previous work [Leontiev, Reuveni, in review] we were able to estimate Meteosat-10 7.3 μm WV pixel values by extracting the mathematical dependency between the WV amount calculated using GPS ZWD and the Meteosat-10 data. Here, we present a new strategy which combines these two approaches for WV estimation by using the mathematical dependency between GPS-ZWD and Meteosat-10 in order to evaluate the WV amount at cloudy conditions when preforming the interpolation between adjusted GPS station inside our network. This approach increases the accuracy of the estimated regional water vapor maps. References: Duan, J. et al. (1996), GPS Meteorology: Direct Estimation of the Absolute Value of Precipitable Water, J. Appl. Meteorol., 35(6), 830-838, doi:10.1175/15200450(1996)035<0830:GMDEOT>2.0.CO;2. Leontiev, A., Reuveni, Y.: Combining METEOSAT-10 satellite image data with GPS tropospheric path delays to estimate regional Integrated Water Vapor (IWV) distribution, Atmos. Meas. Tech. Discuss, doi:10.5194/amt-2016-217, in review, 2016. Schroedter-Homscheidt, M., A. Drews, and S. Heise (2008), Total water vapor column retrieval from MSG-SEVIRI split window measurements exploiting the daily cycle of land surface temperatures, Remote Sens

  18. Assessment of upper tropospheric and stratospheric water vapor and ozone in reanalyses as part of S-RIP

    NASA Astrophysics Data System (ADS)

    Davis, Sean M.; Hegglin, Michaela I.; Fujiwara, Masatomo; Dragani, Rossana; Harada, Yayoi; Kobayashi, Chiaki; Long, Craig; Manney, Gloria L.; Nash, Eric R.; Potter, Gerald L.; Tegtmeier, Susann; Wang, Tao; Wargan, Krzysztof; Wright, Jonathon S.

    2017-10-01

    Reanalysis data sets are widely used to understand atmospheric processes and past variability, and are often used to stand in as "observations" for comparisons with climate model output. Because of the central role of water vapor (WV) and ozone (O3) in climate change, it is important to understand how accurately and consistently these species are represented in existing global reanalyses. In this paper, we present the results of WV and O3 intercomparisons that have been performed as part of the SPARC (Stratosphere-troposphere Processes and their Role in Climate) Reanalysis Intercomparison Project (S-RIP). The comparisons cover a range of timescales and evaluate both inter-reanalysis and observation-reanalysis differences. We also provide a systematic documentation of the treatment of WV and O3 in current reanalyses to aid future research and guide the interpretation of differences amongst reanalysis fields.The assimilation of total column ozone (TCO) observations in newer reanalyses results in realistic representations of TCO in reanalyses except when data coverage is lacking, such as during polar night. The vertical distribution of ozone is also relatively well represented in the stratosphere in reanalyses, particularly given the relatively weak constraints on ozone vertical structure provided by most assimilated observations and the simplistic representations of ozone photochemical processes in most of the reanalysis forecast models. However, significant biases in the vertical distribution of ozone are found in the upper troposphere and lower stratosphere in all reanalyses.In contrast to O3, reanalysis estimates of stratospheric WV are not directly constrained by assimilated data. Observations of atmospheric humidity are typically used only in the troposphere, below a specified vertical level at or near the tropopause. The fidelity of reanalysis stratospheric WV products is therefore mainly dependent on the reanalyses' representation of the physical drivers that

  19. Radiation-Induced Immune Modulation in Prostate Cancer

    DTIC Science & Technology

    2007-01-01

    experiment protocols were approved by the IACUC and the care of animals followed local and national guidelines. The C57BL/6 B16 melanoma and EL4 ...and 1% antibiotics- antimycotic solution (Mediatech, Herndon, VA). The EL4 (MART-1) cell line, an EL4 transfectant carrying the MART-1 cDNA and...chloride buffered (ACK) solution (0.83% (w/v) NH4Cl, 0.14% (w/v) KHCO3, 0.002% Na2EDTA, pH 7.3) and restimulated with heavily irradiated (50 Gy) EL4

  20. Structure-Function Relationship of Hydrophiidae Postsynaptic Neurotoxins

    DTIC Science & Technology

    1990-09-18

    24 hr. Buffer F consisted of 10 mM sodium phosphate, pH 7.5. containing 0.02% (w/v) lauryl sulfate (SDS), and 0.04% (w/v) sodium cholate. The...subjected to gel filtration on Sephadex G-50-50 using 10 mM sodium phosphate buffer (pH 6.5) containing 0.1 M NaCl. Samples were dissolved in 3.5 ml buffer...sequencing. Isolation of Cobrotoxin. The venom from NaJa naia atra was subjected to Sephadex G50-50 gel filtration pre-equilibrated with 10 mM sodium

  1. In-situ photopolymerization of monodisperse and discoid oxidized methacrylated alginate microgels in a microfluidic channel

    DOE PAGES

    Wang, Shuo; Jeon, Oju; Shankles, Peter G.; ...

    2016-02-03

    Here, we present a simple microfluidic technique to in-situ photopolymerize (by 365 nm ultraviolet) monodisperse oxidized methacrylated alginate (OMA) microgels using a photoinitiator (VA-086). By this technique, we generated monodisperse spherical OMA beads and discoid non-spherical beads with better shape consistency than ionic crosslinking methods do. We found that a high monomer concentration (8 w/v %), a high photoinitiator concentration (1.5 w/v %) and absence of oxygen are critical factors to cure OMA microgels. This photopolymerizing method is an alternative to current methods to form alginate microgels and is a simpler approach to generate non-spherical alginate microgels.

  2. Glucose-6-phosphate Reduces Calcium Accumulation in Rat Brain Endoplasmic Reticulum

    DTIC Science & Technology

    2012-04-01

    Ekman and Jager, 1993) adapted from the ammonium molybdate/ malachite green method quan- tified Pi production by SERCA activity. Colorimetric reagent was...prepared by mixing one volume of 10% (w/v) (NH4)6Mo7O24– 4 H2O in 4M HCl with three volumes of 0.2% (w/v) malachite green in 4M HCl, followed by...seryl and threonyl residues in phosphoproteins using alkaline hydrolysis and malachite green. Anal. Biochem. 214, 138. Fulceri, R., Romani, A

  3. Intrinsic Fluorescence as a Spectral Probe for Protein Denaturation Studies in the Presence of Honey

    NASA Astrophysics Data System (ADS)

    Wong, Y. H.; Kadir, H. A.; Tayyab, S.

    2015-11-01

    Honey was found to quench the intrinsic fluorescence of bovine serum albumin (BSA) in a concentration dependent manner, showing complete quenching in the presence of 5% (w/v) honey. Increasing the protein concentration up to 5.0 μM did not lead to the recovery of the protein fluorescence. Urea denaturation of BSA, which otherwise shows a two-step, three-state transition, using intrinsic fluorescence of the protein as the probe failed to produce any result in the presence of 5% (w/v) honey. Thus, intrinsic fluorescence cannot be used as a spectral probe for protein denaturation studies in the presence of honey.

  4. Rapid qualitative and quantitative analysis of opiates in extract of poppy head via FTIR and chemometrics: towards in-field sensors.

    PubMed

    Turner, Nicholas W; Cauchi, Michael; Piletska, Elena V; Preston, Christopher; Piletsky, Sergey A

    2009-07-15

    Identification and quantification of the opiates morphine and thebaine has been achieved in three commercial poppy cultivars using FTIR-ATR spectroscopy, from a simple and rapid methanolic extraction, suitable for field analysis. The limits of detection were 0.13 mg/ml (0.013%, w/v) and 0.3 mg/ml (0.03%, w/v) respectively. The concentrations of opiates present were verified with HPLC-MS. The chemometrics has been used to identify specific "signature" peaks in the poppy IR spectra for characterisation of cultivar by its unique fingerprint offering a potential forensic application in opiate crop analysis.

  5. Tissue-dependent differences in the asynchronous appearance of mast cells in normal mice and in congenic mast cell-deficient mice after infusion of normal bone marrow cells

    PubMed Central

    DU, T; FRIEND, D S; AUSTEN, K F; KATZ, H R

    1996-01-01

    The time courses of the appearance of tissue mast cells in six sites were compared in normal WBB6F1-+/+ mice (+/+) and in congenic mast cell-deficient WBB6F1-W/Wv mice (W/Wv) that received an intravenous infusion of bone marrow cells from +/+mice (BM→W/Wv). As assessed by morphometric analysis of Carnoy's solution-fixed, methylene blue-stained tissue sections, the density of mast cells in the stomach mucosa, stomach submucosa, and spleen of +/+ mice reached maximal levels by 8 weeks of age, whereas the density of mast cells in the skin, extraparenchymal airway walls, and lung parenchyma did not reach maximal levels until 18 weeks of age. When 8-week-old W/Wv mice were infused with 2×107 bone marrow cells from +/+ mice, mast cells appeared in the stomach mucosa and submucosa after 2.5 weeks, in the spleen and extraparenchymal airway walls after 5 weeks, and in the lung parenchyma after 10 weeks. Twenty weeks after bone marrow infusion, the mast cell densities in the spleen, stomach mucosa, and stomach submucosa were seven-, 13-, and five-fold greater, respectively, than those in age-matched +/+ mice, but were eight-, two-, and five-fold lower in the skin, extraparenchymal airway walls, and lung parenchyma, respectively. Thus, those tissues that in +/+ mice reached maximal mast cell densities earlier exhibited abnormally high mast cell densities in BM→W/Wv mice, and those that reached maximal mast cell densities later in +/+ mice had abnormally low mast cell densities in BM→W/Wv mice. Immunological and inflammatory responses are often compared in W/Wv and BM→W/Wv mice to assess mast cell dependency. Our results indicate that the capacity to restore a mast cell-dependent response in a particular tissue of the latter mice may relate to the local mast cell density and whether the immunological challenge activates mast cells only in that tissue or systematically with attendant widespread release of proinflammatory mediators. PMID:8565318

  6. Measuring the turbulent wind vector with a weight-shift Microlight Aircraft

    NASA Astrophysics Data System (ADS)

    Metzger, S.; Junkermann, W.; Neidl, F.; Butterbach-Bahl, K.; Schmid, H. P.; Beyrich, F.; Zheng, X. H.; Foken, T.

    2009-09-01

    The Small Environmental Research Aircraft (SERA) D-MIFUs initial fields of application are aerosol / cloud and radiation transfer research. Therefore a comparatively slow (True Airspeed, TAS ~25 ms-1) but highly mobile microlight aircraft was envisaged. To broaden the application area of D-MIFU we explore whether the microlight can also be used for Eddy Covariance (EC) flux measurement. To obtain useful data sets for airborne EC a reliable turbulent Wind Vector (WV) measurement is a key requirement. Here we present methodology and results to calibrate and express performance and uncertainty of microlight based WV measurement. Specific attention is given to the influence of the flexible-wing weight-shift geometry on the WV measurement. For the WV measurement we equipped D-MIFU with a 70 cm long noseboom supporting a classical 5 hole probe and a fast 50 μm diameter thermocouple. An Inertial Navigation System (INS) supplies high accuracy ground speeds (Ï?=0.05 ms-1) and attitude angles (Ï?=0.03° , 0.1° respectively for heading). Data are stored with 10 Hz yielding a horizontal resolution of 2.5 m. The INS also allows to analyze aircraft dynamics such as 3d rotation rates and acceleration of the nacelle body. Further estimates for 3d acceleration of airfoil and noseboom are obtained at 100 Hz. The noseboom calibration coefficients under laboratory conditions were obtained by wind tunnel- and thermal bath measurements. To transfer these characteristics for in-flight conditions we carried out a series of flights with D-MIFU above the Boundary Layer under calm conditions. On basis of level flights at different power settings we were able to determine dynamic pressure-, sideslip- and attack angle offsets. Additionally forced maneuvers, such as e.g. phugoids, have been performed. By means of multivariate analysis these data are used to assess and minimize the impact of microlight nacelle and airfoil rapidly varying motions (RVM) on the WV components. In the final

  7. The Fernow Experimental Forest and Canaan Valley: A history of research

    Treesearch

    Mary Beth Adams; James N. Kochenderfer

    2015-01-01

    The Fernow Experimental Forest (herein called the Fernow) in Tucker County, WV, was set aside in 1934 for “experimental and demonstration purposes under the direction of the Appalachian Forest Experiment Station” of the US Forest Service. Named after a famous German forester, Bernhard Fernow, the Fernow was initially developed with considerable assistance from the...

  8. The impact of particle size and initial solid loading on thermochemical pretreatment of wheat straw for improving sugar recovery.

    PubMed

    Rojas-Rejón, Oscar A; Sánchez, Arturo

    2014-07-01

    This work studies the effect of initial solid load (4-32 %; w/v, DS) and particle size (0.41-50 mm) on monosaccharide yield of wheat straw subjected to dilute H(2)SO(4) (0.75 %, v/v) pretreatment and enzymatic saccharification. Response surface methodology (RSM) based on a full factorial design (FFD) was used for the statistical analysis of pretreatment and enzymatic hydrolysis. The highest xylose yield obtained during pretreatment (ca. 86 %; of theoretical) was achieved at 4 % (w/v, DS) and 25 mm. The solid fraction obtained from the first set of experiments was subjected to enzymatic hydrolysis at constant enzyme dosage (17 FPU/g); statistical analysis revealed that glucose yield was favored with solids pretreated at low initial solid loads and small particle sizes. Dynamic experiments showed that glucose yield did not increase after 48 h of enzymatic hydrolysis. Once established pretreatment conditions, experiments were carried out with several initial solid loading (4-24 %; w/v, DS) and enzyme dosages (5-50 FPU/g). Two straw sizes (0.41 and 50 mm) were used for verification purposes. The highest glucose yield (ca. 55 %; of theoretical) was achieved at 4 % (w/v, DS), 0.41 mm and 50 FPU/g. Statistical analysis of experiments showed that at low enzyme dosage, particle size had a remarkable effect over glucose yield and initial solid load was the main factor for glucose yield.

  9. DEVELOPMENT OF A FISH INDEX OF BIOTIC INTEGRITY FOR ASSESSING WADEABLE STREAMS IN WEST VIRGINIA

    EPA Science Inventory

    We used Environmental Monitoring Assessment Program (EMAP) data from the Mid-Atlantic Highlands Assessment (MAHA) to develop an Index of Biotic Integrity (IBI) for West Virginia (WV). Standard techniques were used to evaluate a candidate pool of 58 fish assemblage metrics. Resp...

  10. Assessing urban forest effects and values: Morgantown's Urban Forest

    Treesearch

    David J. Nowak; Robert E. III Hoehn; Daniel E. Crane; Jack C. Stevens; Jonathan Cumming; Sandhya Mohen; Anne Buckelew. Cumming

    2012-01-01

    An analysis of the community forest in Morgantown, WV, was undertaken in 2004 to characterize the structural and functional attributes of this forest resource. The assessment revealed that this city has about 658,000 trees with canopies that cover 35.5 percent of the area. The most common tree species are sugar maple, black cherry, and hawthorn. The urban forest...

  11. 13. INTERIOR OF POWER PLANT LOOKING EASTNORTHEAST. 1925 GE GENERATOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. INTERIOR OF POWER PLANT LOOKING EAST-NORTHEAST. 1925 GE GENERATOR IN FOREGROUND, WITH C. 1910 GENERATOR COVER IN BACKGROUND. STEEL FRAME SUPPORTS HOISTING MECHANISM USED TO MOVE, REPAIR, OR REPLACE GENERATORS. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  12. 5. SOUTH ELEVATION OF POWER PLANT BUILDING. GRATE COVERED 'TRASH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. SOUTH ELEVATION OF POWER PLANT BUILDING. GRATE COVERED 'TRASH RACK' VISIBLE IN CENTER. THE STEEL FRAME STRUCTURE SUPPORTS MACHINES TO CLEAR DEBRIS CAUGHT ON THE TRASH RACK. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  13. 16. INTERIOR OF POWER PLANT BUILDING LOOKING SOUTH AT 1925 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. INTERIOR OF POWER PLANT BUILDING LOOKING SOUTH AT 1925 GE GENERATOR. GOVERNOR MECHANISM IN FOREGROUND MANUFACTURED BY THE WOODWARD GOVERNOR COMPANY, ROCKFORD, ILLINOIS (NAMEPLATE ON LEFT). - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  14. 28. EXTERIOR VIEW LOOKING INTO THE SECOND TAILRACE (COUNTING FROM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    28. EXTERIOR VIEW LOOKING INTO THE SECOND TAILRACE (COUNTING FROM THE DOWNSTREAM END TO THE UPSTREAM END SOUTHEAST TO NORTHWEST). NOTE THE STEEL BULKHEAD OF THE FLUME AND THE DRAFT TUBE EXTENDING BENEATH THE SILT DEPOSITS. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  15. 15. INTERIOR OF POWER PLANT LOOKING SOUTHWEST. BACK SIDE OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. INTERIOR OF POWER PLANT LOOKING SOUTHWEST. BACK SIDE OF ELECTRICAL PANEL ON LEFT, AND C. 1910 GENERATOR COVER ON RIGHT. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  16. 27. EXTERIOR VIEW LOOKING INTO THE FIRST TAILRACE (COUNTING FROM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    27. EXTERIOR VIEW LOOKING INTO THE FIRST TAILRACE (COUNTING FROM THE DOWNSTREAM END TO THE UPSTREAM END SOUTHEAST TO NORTHWEST). - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  17. 19. VIEW LOOKING NORTHWEST FROM WITHIN THE ARMORY CANAL WALLS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. VIEW LOOKING NORTHWEST FROM WITHIN THE ARMORY CANAL WALLS AT THE DOWNSREAM SIDE OF THE CONTROL GATES AND LOCK FOR THE CANAL. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  18. 24. CLOSEUP VIEW OF A GRINDSTONE THAT IS LOCATED NEAR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    24. CLOSE-UP VIEW OF A GRINDSTONE THAT IS LOCATED NEAR THE SPILLWAYS OF THE POWER PLANT. THIS GRINDSTONE REMAINS FROM THE ERA WHEN THE STRUCTURE ON THIS SITE FUNCTIONED AS A PULP MILL. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  19. 30. EXTERIOR VIEW LOOKING INTO THE THIRD TAILRACE (COUNTING FROM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    30. EXTERIOR VIEW LOOKING INTO THE THIRD TAILRACE (COUNTING FROM THE DOWNSTREAM END TO THE UPSTREAM END SOUTHEAST TO NORTHWEST). NOTE THE STEEL BULKHEAD OF THE FLUME AND THE DRAFT TUBE EXTENDING BENEATH THE SILT DEPOSITS AND WATER LINE. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  20. 20. VIEW LOOKING SOUTHEAST FROM THE SHORE OF THE POTOMAC ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. VIEW LOOKING SOUTHEAST FROM THE SHORE OF THE POTOMAC RIVER AT THE UPSTREAM SIDE OF THE CONTROL GATES AND LOCK FOR THE ARMORY CANAL. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  1. 21. DETAIL VIEW OF THE OLD ARMORY WALL LOCATED ALONG ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. DETAIL VIEW OF THE OLD ARMORY WALL LOCATED ALONG THE SHORE OF THE POTOMAC SLIGHTLY SOUTHEAST FROM THE SPILLWAYS OF THE POWER PLANT. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  2. Optimization of freeze drying conditions for purified pectinase from mango (Mangifera indica cv. Chokanan) peel.

    PubMed

    Mehrnoush, Amid; Mustafa, Shuhaimi; Yazid, Abdul Manap Mohd

    2012-01-01

    Response surface methodology (RSM) along with central composite design (CCD) was applied to optimize the freeze drying conditions for purified pectinase from mango (Mangifera indica cv. Chokanan) peel. The effect of pectinase content (-2.66, 62.66 mg/mL), Arabic gum (-1.21, 10.21%, w/v), and maltodextrin (0.73, 7.26%, w/v) as independent variables on activity, yield, and storage stability of freeze-dried enzyme was evaluated. Storage stability of pectinase was investigated after one week at 4 °C and yield percentage of the enzyme after encapsulation was also determined. The independent variables had the most significant (p < 0.05) effect on pectinase activity and yield of the enzyme. It was observed that the interaction effect of Arabic gum and maltodextrin improved the enzymatic properties of freeze-dried pectinase. The optimal conditions for freeze-dried pectinase from mango peel were obtained using 30 mg/mL of pectinase content, 4.5 (%, w/v) of Arabic gum, and 4 (%, w/v) of maltodextrin. Under these conditions, the maximum activity (11.12 U/mL), yield (86.4%) and storage stability (84.2%) of encapsulated pectinase were achieved.

  3. Development of low-chromium, chromium-tungsten steels for fusion

    NASA Astrophysics Data System (ADS)

    Klueh, R. L.; Alexander, D. J.; Kenik, E. A.

    1995-12-01

    High-chromium (9-12% Cr) CrMo and CrW ferritic steels are favored as candidates for fusion applications. In early work to develop reduced-activation steels, an Fe2.25Cr2W-0.25V-O.1C steel (designated 2.25Cr-2WV) had better strength than an Fe9Cr2W-0.25V-0.07Tra-0.1C (9Cr-2WVTa) steel (compositions are in weight percent). However, the 2.25Cr-2WV had poor impact properties, as determined by the ductile-brittle transition temperature and upper-shelf energy of subsize Charpy impact specimens. Because low-chromium steels have some advantages over high-chromium steels, a program to develop low-chromium steels is in progress. Microstructural analysis indicated that the reason for the inferior impact toughness of the 2.25Cr-2WV was the granular bainite obtained when the steel was normalized. Properties can be improved by developing an acicular bainite microstructure by increasing the cooling rate after austenitization. Alternatively, acicular bainite can be promoted by increasing the hardenability. Hardenability was changed by adding small amounts of boron and additional chromium to the 2.250-2WV composition. A combination of B, Cr, and Ta additions resulted in low-chromium reduced-activation steels with mechanical properties comparable to those of 9Cr-2WVTa.

  4. Thymol nanoemulsified by whey protein-maltodextrin conjugates: the enhanced emulsifying capacity and antilisterial properties in milk by propylene glycol.

    PubMed

    Xue, Jia; Davidson, P Michael; Zhong, Qixin

    2013-12-26

    The objective of this research was to enhance the capability of whey protein isolate-maltodextrin conjugates in nanoemulsifying thymol using propylene glycol to improve antilisterial properties in milk. Thymol was predissolved in PG and emulsified in 7% conjugate solution. Transparent dispersions with mean diameters of <30 nm were observed up to 1.5%w/v thymol. In skim and 2% reduced fat milk, Listeria monocytogenes Scott A was reduced from ∼5 log CFU/mL to below the detection limit in 6 h by 0.1% w/v and 0.45% w/v nanoemulsified thymol, respectively, contrasting with gradual reductions to 1.15 and 2.26 log CFU/mL after 48 h by same levels of free thymol. In full fat milk, L. monocytogenes was gradually reduced to be undetectable after 48 h by 0.6% w/v nanoemulsified thymol, contrasting with the insignificant reduction by free thymol. The improved antilisterial activities of nanoemulsified thymol resulted from the increased solubility in milk and synergistic activity with propylene glycol.

  5. In vivo evaluation of an oral delivery system for P-gp substrates based on thiolated chitosan.

    PubMed

    Föger, Florian; Schmitz, Thierry; Bernkop-Schnürch, Andreas

    2006-08-01

    Recently, thiolated polymers, so called thiomers, have been reported to modulate drug absorption by inhibition of intestinal P-glycoprotein (P-gp). The aim of the present study was to provide a proof-of-principle for a delivery system based on thiolated chitosan in vivo in rats, using rhodamine-123 (Rho-123) as representative P-gp substrate. In vitro, the permeation enhancing effect of unmodified chitosan, chitosan-4 thiobutylamidine (Ch-TBA) and the combination of Ch-TBA with reduced glutathione (GSH) was evaluated by using freshly excised rat intestinal mucosa mounted in Ussing-type chambers. In comparison to buffer only, Rho-123 transport in presence of 0.5% (w/v) chitosan, 0.5% (w/v) Ch-TBA and the combination of 0.5% (w/v) Ch-TBA/0.5% (w/v) GSH, was 1.8-fold, 2.6-fold, 3.8-fold improved, respectively. Furthermore, enteric-coated tablets based on unmodified chitosan or Ch-TBA/GSH, were investigated in vivo. In rats, the Ch-TBA/GSH tablets increased the area under the plasma concentration time curve (AUC0-12) of Rho-123 by 217% in comparison to buffer control and by 58% in comparison to unmodified chitosan. This in vivo study showed that a delivery system based on thiolated chitosan significantly increased the oral bioavailability of P-gp substrate Rho-123.

  6. 2. Credit PEM. View of Martinsburg Power Company steam generating ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Credit PEM. View of Martinsburg Power Company steam generating plant. From right to left: original 1889 generating building, transformer room, new generating room and, adjacent to draft stack is boiler room addition. Photo c. 1911. - Dam No. 4 Hydroelectric Plant, Potomac River, Martinsburg, Berkeley County, WV

  7. 1. AERIAL VIEW OF SHOPS COMPLEX LOOKING EAST SHOWING WEST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. AERIAL VIEW OF SHOPS COMPLEX LOOKING EAST SHOWING WEST AND EAST ROUNDHOUSES, FROG AND SWITCH SHOP, AND MACHINE SHOP. - Baltimore & Ohio Railroad, Martinsburg Repair Shops, West Side of Tuscarora Creek Opposite East End of Race Street, Martinsburg, Berkeley County, WV

  8. Nitrogen (N) dynamics in the mineral soil of a Central Appalachian hardwood forest during a quarter century of whole-watershed N additions

    Treesearch

    Frank S. ​Gilliam; Christopher A. Walter; Mary Beth Adams; William T. Peterjohn

    2018-01-01

    The structure and function of terrestrial ecosystemsare maintained by processes that vary with temporal and spatial scale. This study examined temporal and spatial patterns of net nitrogen (N) mineralization and nitrification in mineral soil of three watersheds at the Fernow Experimental Forest, WV: 2 untreated watersheds and 1 watershed receiving aerial applications...

  9. Use of a mixture of n-dodecyl-beta-D-maltoside and sodium dodecyl sulfate in poly(dimethylsiloxane) microchips to suppress adhesion and promote separation of proteins.

    PubMed

    Huang, Bo; Kim, Samuel; Wu, Hongkai; Zare, Richard N

    2007-12-01

    Dynamic modification of poly(dimethylsiloxane) channels using a mixture of n-dodecyl-beta-D-maltoside (DDM) and sodium dodecyl sulfate (SDS) is able to suppress analyte adsorption and control electroosmotic flow (EOF). In this mixed surfactant system, the nonionic surfactant DDM functions as a surface blocking reagent, whereas the anionic surfactant SDS introduces negative charges to the channel walls. Changing the DDM/SDS mixing ratio tunes the surface charge density and the strength of EOF. Using 0.1% (w/v) DDM and 0.03% (w/v) SDS, Alexa Fluor 647 labeled streptavidin can be analyzed according to the charges added by the fluorophores. Protein molecules with different numbers of fluorophores are well resolved. DDM and SDS also form negatively charged mixed micelles, which act as a separation medium. The low critical micellar concentration of DDM/SDS mixed micelles also allows the use of SDS at a nondenaturing concentration, which enables the analysis of proteins in their native state. The immunocomplex between a membrane protein, beta2 adrenergic receptor, and anti-FLAG antibody has been fully separated using 0.1% (w/v) DDM and 0.03% (w/v) SDS. We have also analyzed the composition of light-harvesting protein-chromophore complexes in cyanobacteria.

  10. Application of High-Temperature Superconducting Thin-Film Devices to Electro-Optical and Electronic Warfare Systems

    DTIC Science & Technology

    1990-02-01

    of the fundamentals and types of’ Josephson T~ ko important parameters that help to characterize theIjuncticos is gi\\enbh\\ Iinkhiain" itand x ill not be...Opry sko , J. D. Of T1. Ca, Ba, CL1, , Produced by Chemical Deposi- Mannhart, B. Bumble, G. J. Clark, WV. J. Gallagher, nion avd Laser Ablation,’ Workshop

  11. Topical Hazard Evaluation Program of Candidate Insect Repellent A13-38349a US Department of Agriculture Proprietary Chemicals, July 1981-January 1983.

    DTIC Science & Technology

    1983-08-16

    reaction (w/v) Oil of Bergamot irritation reaction under test (positive control) in 95% under test conditions and is ethyl alcohol was conditions, not...the rabbits, 0.05 mL cation and irradiation of the test chemical, caused greater irritant positive control (oil of effects than in un- Bergamot ) and

  12. Topical Hazard Evaluation Program of Candidate Insect Repellents AI3-38352a, AI3-38354a, AI3-38355a, US Department of Agriculture Proprietary Chemicals, May 1982 - November 1983.

    DTIC Science & Technology

    1983-11-01

    irrita- chemical and of 10% (wv) A13-38357a, AI3-38360a, tion reaction under Oil of Bergamot (positive and Ar3-38361a did test conditions and control...caused a greater Irritant positive control (Oil of effect than In un- Bergamot ) and diluent were Irradiated skin areas. applied to additional skin

  13. 77 FR 63340 - Agency Information Collection Activities; Proposed Collection; Comments Requested: FEL Out-of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-16

    ... business or operation is discontinued and succeeded by a new licensee or new permittee to reflect that fact... operation is absolute, deliver records to any ATF office located in the region in which the business or operation was located or to ATF Out of Business Records Center, 244 Needy Road, Martinsburg, WV 25405 within...

  14. Yerba mate tea and mate saponins prevented azoxymethane-induced inflammation of rat colon through suppression of NF-kB p65ser(311) signaling via IkB-a and GSK-3ß reduced phosphorylation

    USDA-ARS?s Scientific Manuscript database

    Yerba mate tea (YMT) has a chemopreventive role in a variety of inflammatory diseases. The objective was to determine the capability of YMT and mate saponins to prevent azoxymethane (AOM)-induced colonic inflammation in rats. YMT (2% dry leaves, w/v, as a source of drinking fluid) (n = 15) and mat...

  15. Protective actions of green tea polyphenols and alfacalcidol on bone microstructure in female rats with chronic inflammation

    USDA-ARS?s Scientific Manuscript database

    This study investigated the effects of green tea polyphenols (GTP) and alfacalcidol on bone microstructure and strength along with possible mechanisms in rats with chronic inflammation. A 12-week study using a 2 (no GTP vs. 0.5%, w/v GTP in drinking water) × 2 (no alfacalcidol vs. 0.05 ug/kg alfacal...

  16. 76 FR 21387 - Federal Property Suitable as Facilities To Assist the Homeless

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-15

    ... GSA Number: 4-G-WV-0557 Comments: 57,600 sq. ft; future owners must maintain exposure prevention... Number: 9-N-CA-1508-AI Comments: Correction: 631.62 sq. ft., encroachment. Parcel F-4 Right of Way Seal...

  17. The Glenwood Estate: our 32-year experience using Arbotect® 20-S to control Dutch elm disease

    Treesearch

    William L. MacDonald; Mark L. Double; Cameron M. Stauder; Kemp. Winfree

    2017-01-01

    We report a case study that demonstrates the successful use of the fungicide Arbotect® 20-S to protect American elms (Ulmus americana) from Dutch elm disease at a historic site in Charleston, WV. Standard injection protocols were used every 3 to 4 years to deliver the chemical into the root flares. Twelve of the original 16 trees remain 34 years...

  18. 1. Photocopy of map (from The Virginia Springs, and the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Photocopy of map (from The Virginia Springs, and the Springs of the South and West by Moorman) No date 'MAP OF ROUTES AND DISTANCES TO THE VIRGINIA SPRINGS' - White Sulphur Springs, U.S. Route 60, White Sulphur Springs, Greenbrier County, WV

  19. 3. SHOWING STREAM, STORE BUILDING (UPPER LEFT), SPRING HOUSE AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. SHOWING STREAM, STORE BUILDING (UPPER LEFT), SPRING HOUSE AND BATH HOUSE (NEAR STREAM), SOUTHEAST FRONTS AND SOUTHWEST SIDES (4 x 5 negative; 5 x 7 print) - Salt Sulpher Springs, U.S. Route 219, Salt Sulphur Springs, Monroe County, WV

  20. Principal and Faculty Senate Chair Perceptions of Faculty Senate Participation in Teacher Hiring in West Virginia Schools

    ERIC Educational Resources Information Center

    Grose, Sarah Elizabeth

    2017-01-01

    The purpose of this study was to assess principals' and faculty senate chairs' perceptions of the effectiveness of WV BOE Policy 5000: Procedures for Designated Hiring and Transfer of School Personnel, in improving teacher hiring practices in West Virginia schools. Enacted on September 16, 2013, West Virginia's schools were required by state…

  1. Production of ethanol and xylitol from corn cobs by yeasts.

    PubMed

    Latif, F; Rajoka, M I

    2001-03-01

    Saccharomyces cerevisiae and Candida tropicalis were used separately and as co-culture for simultaneous saccharification and fermentation (SSF) of 5-20% (w/v) dry corn cobs. A maximal ethanol concentration of 27, 23, 21 g/l (w/v) from 200 g/l (w/v) dry corn cobs was obtained by S. cerevisiae, C. tropicalis and the co-culture, respectively, after 96 h of fermentation. However, theoretical yields of 82%, 71% and 63% were observed from 50 g/l dry corn cobs for the above cultures, respectively. Maximal xylitol concentration of 21, 20 and 15 g/l from 200 g/l (w/v) dry corn cobs was obtained by C. tropicalis, co-culture, and S. cerevisiae, respectively. Maximum theoretical yields of 79.0%, 77.0% and 58% were observed from 50 g/l of corn cobs, respectively. The volumetric productivities for ethanol and xylitol increased with the increase in substrate concentration, whereas, yield decreased. Glycerol and acetic acid were formed as minor by-products. S. cerevisiae and C. tropicalis resulted in better product yields (0.42 and 0.36 g/g) for ethanol and (0.52 and 0.71 g/g) for xylitol, respectively, whereas, the co-culture showed moderate level of ethanol (0.32 g/g) and almost maximal levels of xylitol (0.69 g/g).

  2. 47 CFR 78.19 - Interference.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) Radio Astronomy and Radio Research Installations. In order to minimize harmful interference at the National Radio Astronomy Observatory site located at Green Bank, Pocahontas County, W. Va., and at the... Astronomy Observatory, Post Office Box No. 2, Green Bank, WV 24944, in writing, of the technical particulars...

  3. 47 CFR 78.19 - Interference.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) Radio Astronomy and Radio Research Installations. In order to minimize harmful interference at the National Radio Astronomy Observatory site located at Green Bank, Pocahontas County, W. Va., and at the... Astronomy Observatory, Post Office Box No. 2, Green Bank, WV 24944, in writing, of the technical particulars...

  4. 47 CFR 78.19 - Interference.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) Radio Astronomy and Radio Research Installations. In order to minimize harmful interference at the National Radio Astronomy Observatory site located at Green Bank, Pocahontas County, W. Va., and at the... Astronomy Observatory, Post Office Box No. 2, Green Bank, WV 24944, in writing, of the technical particulars...

  5. 47 CFR 78.19 - Interference.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) Radio Astronomy and Radio Research Installations. In order to minimize harmful interference at the National Radio Astronomy Observatory site located at Green Bank, Pocahontas County, W. Va., and at the... Astronomy Observatory, Post Office Box No. 2, Green Bank, WV 24944, in writing, of the technical particulars...

  6. 47 CFR 78.19 - Interference.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...) Radio Astronomy and Radio Research Installations. In order to minimize harmful interference at the National Radio Astronomy Observatory site located at Green Bank, Pocahontas County, W. Va., and at the... Astronomy Observatory, Post Office Box No. 2, Green Bank, WV 24944, in writing, of the technical particulars...

  7. TWO OF THE FORTYSIX EXTANT BEEHIVE COKE OVENS CONSTRUCTED BY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    TWO OF THE FORTY-SIX EXTANT BEEHIVE COKE OVENS CONSTRUCTED BY JOHN NUTTALL DURING THE EARLY 1870S, LOOKING NORTHWEST - Nuttallburg Mine Complex, Coke Ovens, North side of New River, 2.7 miles upstream from Fayette Landing, Lookout, Fayette County, WV

  8. Pine Shoot Beetle Research Update

    Treesearch

    Robert A. Haack; Therese M. Poland

    2000-01-01

    Established populations of the pine shoot beetle, Tomicus piniperda (L.) (Coleoptera: Scolytidae), were first detected in the US in 1992. As of January 2000, T. piniperda was known to be established in 271 counties in 11 US states (IL, IN, MD, MI, NH, NY, OH, PA, VT, WI, WV) and 25 counties in Ontario and 8 counties in Quebec,...

  9. Assessment of spatiotemporal fusion algorithms for Planet and Worldview images

    USDA-ARS?s Scientific Manuscript database

    Although Worldview (WV) images (non-pansharpened) have 2-meter resolution, the re-visit times for the same areas may be 7 days or more. In contrast, Planet images using small satellites can cover the whole Earth almost daily. However, the resolution of Planet images is 3.125 m. It will be ideal to f...

  10. Optimization of Freeze Drying Conditions for Purified Pectinase from Mango (Mangifera indica cv. Chokanan) Peel

    PubMed Central

    Mehrnoush, Amid; Mustafa, Shuhaimi; Yazid, Abdul Manap Mohd

    2012-01-01

    Response surface methodology (RSM) along with central composite design (CCD) was applied to optimize the freeze drying conditions for purified pectinase from mango (Mangifera indica cv. Chokanan) peel. The effect of pectinase content (−2.66, 62.66 mg/mL), Arabic gum (−1.21, 10.21%, w/v), and maltodextrin (0.73, 7.26%, w/v) as independent variables on activity, yield, and storage stability of freeze-dried enzyme was evaluated. Storage stability of pectinase was investigated after one week at 4 °C and yield percentage of the enzyme after encapsulation was also determined. The independent variables had the most significant (p < 0.05) effect on pectinase activity and yield of the enzyme. It was observed that the interaction effect of Arabic gum and maltodextrin improved the enzymatic properties of freeze-dried pectinase. The optimal conditions for freeze-dried pectinase from mango peel were obtained using 30 mg/mL of pectinase content, 4.5 (%, w/v) of Arabic gum, and 4 (%, w/v) of maltodextrin. Under these conditions, the maximum activity (11.12 U/mL), yield (86.4%) and storage stability (84.2%) of encapsulated pectinase were achieved. PMID:22489134

  11. 12. INTERIOR VIEW OF SINGLE BAY SLOTTED TYPE FURNACE (LEFT) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. INTERIOR VIEW OF SINGLE BAY SLOTTED TYPE FURNACE (LEFT) AND CHAMBERSBURG DROP HAMMER OPERATED BY JEFF HOHMAN (RIGHT); THE FURNACE IS USED TO PRE-HEAT THE STEEL PRIOR TO FORGING, TOOL IS POST HOLE DIGGER WITH TAMPING BAR - Warwood Tool Company, Foot of Nineteenth Street, Wheeling, Ohio County, WV

  12. Production of schizophyllan from distiller's dried grains with solubles by diverse strains of Schizophyllan commune

    USDA-ARS?s Scientific Manuscript database

    Eleven diverse strains of Schizophyllan commune, to our knowledge never before examined for production of the biopolymer schizophyllan, were grown in malt extract (ME) basal medium containing 1.0% (w/v) distiller’s dried grains with solubles (DDGS, an abundant coproduct of fuel ethanol production by...

  13. Does nitrogen and sulfur deposition affect forest productivity?

    Treesearch

    Brittany A. Johnson; Kathryn B. Piatek; Mary Beth Adams; John R. Brooks

    2010-01-01

    We studied the effects of atmospheric nitrogen and sulfur deposition on forest productivity in a 10-year-old, aggrading forest stand at the Fernow Experimental Forest in Tucker County, WV. Forest productivity was expressed as total aboveground wood biomass, which included stem and branch weight of standing live trees. Ten years after stand regeneration and treatment...

  14. 30 CFR 46.3 - Training plans.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR EDUCATION AND TRAINING TRAINING AND..., National Mine Health and Safety Academy, 1301 Airport Road, Beaver, WV 25813-9426, Telephone: (304) 256... responsible for the health and safety training at the mine. This person may be the production-operator or...

  15. 77 FR 40945 - Qualification of Drivers; Exemption Applications; Vision

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-11

    .... Berkheimer (PA) Michael D. DeBerry (WV) Tony K. Ellis (IN) Jerry L. Gibson (FL) Rici W. Giesseman (OH) George.... McClain (MI) Daniel E. Miller (VA) Buddy W. Myrick (TX) James L. Okonek (WI) Aaron L. Paustian (IA) John J. Pribanic (TX) Alan J. Reynaldos (NJ) Charles L. Rill, Sr. (MD) John P. Rodrigues (TX) Robert Smiley (NM...

  16. Local residents' attitudes toward potential tourism development: the case of Ansted, West Virginia

    Treesearch

    Maureen Y. Bender; Jinyang Deng; Steve Selin; Doug Arbogast; R.A. Hobbs

    2009-01-01

    The purpose of this study was to understand residents' attitudes toward tourism development in the town of Ansted, WV, using self-administered surveys. The attitude assessment in this study was part of a tourism planning process conducted for the town. The results indicate that perceptions of tourism development among Ansted's residents are generally...

  17. Contrasts in carbon and nitrogen ecosystem budgets in adjacent Norway spruce and Appalachian hardwood watersheds in the Fernow Experimental Forest, West Virginia

    Treesearch

    Charlene Kelly; Stephen Schoenholtz; Mary Beth Adams

    2011-01-01

    We constructed watershed mass-balance budgets of carbon (C) and nitrogen (N) and measured seasonal net N mineralization in an attempt to account for nearly 40 years of large discrepancies in stream NO3-N export in two adjacent, gauged watersheds at the U.S. Department of Agriculture Forest Service's Fernow Experimental Forest, WV. These...

  18. 49. INTERIOR VIEW OF HARDENER AREA SHOWING GAUGE THAT MEASURES ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    49. INTERIOR VIEW OF HARDENER AREA SHOWING GAUGE THAT MEASURES HARDNESS, THE NAIL MUST BREAK IN THE CENTER RANGE OF THE CURVED BAR TO HAVE THE CORRECT HARDNESS (THE NAIL WILL BREAK TOO EASILY IF TOO HARD AND WILL BEND TOO MUCH IF TOO SOFT) - LaBelle Iron Works, Thirtieth & Wood Streets, Wheeling, Ohio County, WV

  19. Synthesis, kinetics and photocatalytic study of "ultra-small" Ag-NPs obtained by a green chemistry method using an extract of Rosa 'Andeli' double delight petals.

    PubMed

    Suárez-Cerda, Javier; Alonso-Nuñez, Gabriel; Espinoza-Gómez, Heriberto; Flores-López, Lucía Z

    2015-11-15

    This paper reports the effect of different concentrations of Rosa 'Andeli' double delight petals aqueous extract (PERA) in the synthesis of silver nanoparticles (Ag-NPs), using an easy green chemistry method. Its kinetics study and photocatalytic activity were also evaluated. The Ag-NPs were obtained using an aqueous silver nitrate solution (AgNO3) with 9.66% w/v, 7.25% w/v, and 4.20% w/v PERA as both reducing-stabilizing agent. The formation of the Ag-NPs was demonstrated by analysis of UV-vis spectroscopy, scanning electron microscopy-energy dispersive spectroscopy (SEM-EDS) and transmission electron microscopy (TEM). TEM analysis shows spherical nanoparticles in shape and size between ∼0.5 and 1.4nm. A comparative study was done to determine which concentration was the best reducing-stabilizing agent, and we found out that "ultra-small" nanoparticles (0.5-1.1nm) were obtained with 9.66% w/v of PERA. The size of the Ag-NPs depends on the concentration of PERA and Ag(I). The reaction of formation of "ultra-small" Ag-NPs, proved to be first order for metallic precursor (silver) and second order for reducing-stabilizing agent (PERA). The Ag-NPs showed photocatalytic activity, in degradation of commercial dye with an efficiency of 95%. Copyright © 2015 Elsevier Inc. All rights reserved.

  20. LiDAR Point Cloud and Stereo Image Point Cloud Fusion

    DTIC Science & Technology

    2013-09-01

    LiDAR point cloud (right) highlighting linear edge features ideal for automatic registration...point cloud (right) highlighting linear edge features ideal for automatic registration. Areas where topography is being derived, unfortunately, do...with the least amount of automatic correlation errors was used. The following graphic (Figure 12) shows the coverage of the WV1 stereo triplet as

  1. Through-vial impedance spectroscopy of critical events during the freezing stage of the lyophilization cycle: the example of the impact of sucrose on the crystallization of mannitol.

    PubMed

    Arshad, Muhammad Sohail; Smith, Geoff; Polygalov, Eugene; Ermolina, Irina

    2014-08-01

    The aim of this work was to evaluate the application of through-vial impedance spectroscopy in the measurement of eutectic crystallization during the freezing stage of the lyophilisation cycle. Impedance measurements of various sugar solutions (mannitol 5%, 10% and 15% w/v, sucrose 5% w/v and mannitol 5% w/v, and sucrose 5% w/v solutions) were taken during a freeze-thaw cycle, over a frequency range 10-10(6) Hz with a scan interval of 1.5 min, using measurement vials with externally attached electrodes connected to a high resolution impedance analyzer. Estimates for the electrical resistance of the mannitol solutions record the exothermic crystallization of mannitol at a temperature of -24 °C during the temperature ramp down stage of the freezing cycle, which is in close agreement with the off-line DSC measurement of -22 °C. The freezing profile of a 5% mannitol solution with 5% sucrose (a component that does not crystallize in the frozen solution) demonstrated the inhibition of mannitol crystallization (with the implication that the product will then require sub-Tg' freezing and drying). The work suggests a role for through-vial impedance spectroscopy in the concurrent development of the product formulation and freeze drying cycle without the uncertainty introduced when using off-line date to define the critical process parameters. Copyright © 2014 Elsevier B.V. All rights reserved.

  2. Effect of zinc oxide on the rheological and mucoadhesive properties of poloxamer 407-based mucoadhesive thermosensitive gel.

    PubMed

    Park, Tae-Hwan; Kim, Sung Tae; Park, Jeong-Sook; Choi, Han-Gon; Kim, Hyung Tae; Kim, Chong-Kook

    2010-12-01

    To improve the therapeutic efficacy of drugs for hemorrhoid, mucoadhesive thermosensitive gel (MTG) system was developed. The MTG was prepared using poloxamer 407 (P407, 13% and 14%), polycarbophil (PC, 0.2% w/v), phenylephrine hydrochloride (0.25% w/v), lidocaine hydrochloride (1.88% w/v), and prednisolone acetate (0.05% w/v). Then, zinc oxide (ZnO) was added as an astringent as well as mucoadhesiveness-enhancing agent. Two kinds of poloxamer-based MTGs were compared in aspects of rheology, mucoadhesiveness, syringeability, and in vitro release study. Both the two MTGs (13% and 14% P407) showed Newtonian behavior at 20°C whereas pseudoplastic flow at 37°C. The addition of ZnO into MTGs enhanced the mucoadhesiveness and syringeability and led the drug components to be released in accordance with Fickian mechanism. Taken together, the MTG-containing ZnO can be a more effective and convenient delivery system for the treatment of hemorrhoid with a reduced dosage interval.

  3. 22. PHOTOGRAPHIC ENLARGEMENT OF UPPER PHOTOGRAPH ON PAGE 986 IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. PHOTOGRAPHIC ENLARGEMENT OF UPPER PHOTOGRAPH ON PAGE 986 IN Keystone Coal Buyers Catalog, 1922, VIEW SOUTH, COMMUNITY OF ETHEL; ETHEL COAL COMPANY MINE SUPPLY BUILDING IS LOCATED IN MID-GROUND LEFT OF CENTER PARTIALLY OBSCURED BY ROOF OF HOUSE IN FOREGROUND - Ethel Coal Company & Supply Building, Left fork of Dingess Run (Ethel Hollow), Ethel, Logan County, WV

  4. 23. PHOTOGRAPHIC ENLARGEMENT OF UPPER PHOTOGRAPH ON PAGE 986 IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    23. PHOTOGRAPHIC ENLARGEMENT OF UPPER PHOTOGRAPH ON PAGE 986 IN Keystone Coal Buyers Catalog, 1922, VIEW SOUTH, COMMUNITY OF ETHEL; ETHEL COAL COMPANY MINE SUPPLY BUILDING IS LOCATED IN MID-GROUND IN CENTER PARTIALLY OBSCURED BY ROOF OF HOUSE IN FOREGROUND - Ethel Coal Company & Supply Building, Left fork of Dingess Run (Ethel Hollow), Ethel, Logan County, WV

  5. 21. PHOTOGRAPH OF PAGE 986 IN Keystone Coal Buyers Catalog, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. PHOTOGRAPH OF PAGE 986 IN Keystone Coal Buyers Catalog, 1922, UPPER PHOTOGRAPH, VIEW SOUTH, COMMUNITY OF ETHEL; ETHEL COAL COMPANY MINE SUPPLY BUILDING IS LOCATED IN MID-GROUND LEFT OF CENTER PARTIALLY OBSCURED BY ROOF OF HOUSE IN FOREGROUND - Ethel Coal Company & Supply Building, Left fork of Dingess Run (Ethel Hollow), Ethel, Logan County, WV

  6. 8. INTERIOR, DETAIL OF HOUSE COAL CONVEYOR IN LOADING ROOM, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. INTERIOR, DETAIL OF HOUSE COAL CONVEYOR IN LOADING ROOM, USED TO CONVEY COAL TO A STORAGE HOPPER AND MADE AVAILABLE TO NUTTALLBURG RESIDENTS, LOOKING WEST - Nuttallburg Mine Complex, Tipple, North side of New River, 2.7 miles upstream from Fayette Landing, Lookout, Fayette County, WV

  7. 7. INTERIOR, ROBERTS AND SCHAEFER SHAKER TABLE (LEFT), MARYLAND NEW ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. INTERIOR, ROBERTS AND SCHAEFER SHAKER TABLE (LEFT), MARYLAND NEW RIVER COAL COMPANY INSTALLED APRON CONVEYOR (RIGHT) USED TO CONVEY COAL TO THE BELKNAP CHORIDE WASHER, RETURN CHUTE FOR CLEANED COAL (FAR RIGHT), AND COAL STORAGE SILO (BACKGROUND), LOOKING WEST - Nuttallburg Mine Complex, Tipple, North side of New River, 2.7 miles upstream from Fayette Landing, Lookout, Fayette County, WV

  8. 4. NORTH ELEVATION, SHOWING COLLAPSED MARYLAND NEW RIVER COAL COMPANY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. NORTH ELEVATION, SHOWING COLLAPSED MARYLAND NEW RIVER COAL COMPANY ADDITION, WITH REFUSE CONVEYOR (FOREGROUND), TIMBER REFUSE BIN (LEFT), CONVEYOR HOUSE AND SCREENING ROOM (CENTER), AND COAL STORAGE SILO (RIGHT), LOOKING EAST - Nuttallburg Mine Complex, Tipple, North side of New River, 2.7 miles upstream from Fayette Landing, Lookout, Fayette County, WV

  9. Can Satellite Remote Sensing be Applied in Geological Mapping in Tropics?

    NASA Astrophysics Data System (ADS)

    Magiera, Janusz

    2018-03-01

    Remote sensing (RS) techniques are based on spectral data registered by RS scanners as energy reflected from the Earth's surface or emitted by it. In "geological" RS the reflectance (or emittence) should come from rock or sediment. The problem in tropical and subtropical areas is a dense vegetation. Spectral response from the rocks and sediments is gathered only from the gaps among the trees and shrubs. Images of high resolution are appreciated here, therefore. New generation of satellites and scanners (Digital Globe WV2, WV3 and WV4) yield imagery of spatial resolution of 2 m and up to 16 spectral bands (WV3). Images acquired by Landsat (TM, ETM+, OLI) and Sentinel 2 have good spectral resolution too (6-12 bands in visible and infrared) and, despite lower spatial resolution (10-60 m of pixel size) are useful in extracting lithological information too. Lithological RS map may reveal good precision (down to a single rock or outcrop of a meter size). Supplemented with the analysis of Digital Elevation Model and high resolution ortophotomaps (Google Maps, Bing etc.) allows for quick and cheap mapping of unsurveyed areas.

  10. 75 FR 52437 - IFR Altitudes; Miscellaneous Amendments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-26

    ... Part GORDONSVILLE, VA VORTAC LURAY, VA FIX 6100 LURAY, VA FIX *KERRE, VA FIX **6000 *7000--MRA **5000--MOCA *KERRE, VA FIX MARTINSBURG, WV VORTAC.. **6000 *7000--MRA **5000--MOCA Sec. 95.6005 VOR Federal... GORDONSVILLE, VA VORTAC LURAY, VA FIX 6100 LURAY, VA FIX *KERRE, VA FIX **6000 *7000--MRA **5000--MOCA *KERRE...

  11. 76 FR 21622 - IFR Altitudes; Miscellaneous Amendments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-18

    ...--MRA **1700--MOCA Sec. 95.6044 VOR Federal Airway V44 Is Amended To Read in Part BENDS, WV FIX... VORTAC *PRATZ, GA FIX 2500 *3000--MRA PRATZ, GA FIX MACON, GA *2500 VORTAC. *GNSS MEA MACON R-265... *RAGGS, CA FIX **BESSA, CA FIX......... **8500 *8500--MRA **8500--MCA BESSA, CA FIX, S BND **4800--MOCA...

  12. Object based image analysis for the classification of the growth stages of Avocado crop, in Michoacán State, Mexico

    NASA Astrophysics Data System (ADS)

    Gao, Yan; Marpu, Prashanth; Morales Manila, Luis M.

    2014-11-01

    This paper assesses the suitability of 8-band Worldview-2 (WV2) satellite data and object-based random forest algorithm for the classification of avocado growth stages in Mexico. We tested both pixel-based with minimum distance (MD) and maximum likelihood (MLC) and object-based with Random Forest (RF) algorithm for this task. Training samples and verification data were selected by visual interpreting the WV2 images for seven thematic classes: fully grown, middle stage, and early stage of avocado crops, bare land, two types of natural forests, and water body. To examine the contribution of the four new spectral bands of WV2 sensor, all the tested classifications were carried out with and without the four new spectral bands. Classification accuracy assessment results show that object-based classification with RF algorithm obtained higher overall higher accuracy (93.06%) than pixel-based MD (69.37%) and MLC (64.03%) method. For both pixel-based and object-based methods, the classifications with the four new spectral bands (overall accuracy obtained higher accuracy than those without: overall accuracy of object-based RF classification with vs without: 93.06% vs 83.59%, pixel-based MD: 69.37% vs 67.2%, pixel-based MLC: 64.03% vs 36.05%, suggesting that the four new spectral bands in WV2 sensor contributed to the increase of the classification accuracy.

  13. 49 CFR 7.42 - What is DOT's fee schedule for records requested under subpart C of this part?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    .../programmer time, and time spent reviewing records, when performed by employees, based on the grades and rates..., DC-MD-VA-WV-PA, or equivalent grades, plus 16% to cover fringe benefits, as follows: (1) GS-1 through... scientific institution whose purpose is scholarly or scientific research (and not for a commercial use); (3...

  14. Role of Inflammation in MPTP-Induced Dopaminergic Degeneration

    DTIC Science & Technology

    2005-12-01

    8217Department of Developmental Neurohiolog/, Saint Jude Children k Research Hospital, Memphis, TN 39105. USA "tNeuroscience Research Laboratories qf...astrucytes. J. Neuror’heo,. 68. 2216-22)9. Lannsion 1WV, LS Porno . J Te~trud, AG Reeves. JA Kaplan and 1) Lichent C J Arsaur. [R Vaulter and J Dernores

  15. The influence of selected excipients on the rheological behaviour of chitosan based ocular pharmaceutical systems

    NASA Astrophysics Data System (ADS)

    Budai, L.; Szabadi, E.; Hajdú, M.; Budai, M.; Klebovich, I.; Antal, I.

    2015-04-01

    Aims: Chitosan, a modified natural carbohydrate polymer, has received great attention in diverse scientific fields including pharmaceutical and biomedical research areas. Besides its low toxicity, mucoadhesiveness and biodegradability its special favourable rheological feature makes it a unique gelling agent for the design of ocular systems. Chitosan based (2.0 w/v %) ocular systems containing selected excipients were formulated in order to investigate the rheological influence of applied auxiliary materials. Rotational and oscillatory rheological properties of propylene glycol (1.0-20.0 w/v %), glycerin (1.0-5.0 w/v %) and castor oil (1.0-5.0 w/v %) containing chitosan gels were evaluated. The rheological behaviour of formulated ocular gels were compared before and after steam sterilization. Methods: Rotational and oscillatory rheological measurements were carried out with Kinexus Pro Rheometer. Comparison of flow curves and oscillatory frequency sweep measurements in the linear viscoelastic region made possible the evaluation of rheological effect of selected excipients. Results: In the applied concentration range the effect of propylene glycol among the selected excipients presents the most significant impact on rheology of chitosan formulations. Steam sterilization results in reduced viscosity in most of chitosan gels. However, the presence of polyols appears to prevent the degradation of chitosan after steam sterilization.

  16. 2. Photocopy of photograph, c. 1904. VIEW OF TAILRACE ELEVATION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Photocopy of photograph, c. 1904. VIEW OF TAILRACE ELEVATION OF ORIGINAL MARTINSBURG POWER COMPANY POWER HOUSE AT DAM NO. 5. (Courtesy of the Potomac Edison Company Library, Historical Data Files, Dam No. 5 listing) - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  17. 46. Photocopy of photograph, c. 1933. VIEW OF DAM AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    46. Photocopy of photograph, c. 1933. VIEW OF DAM AND FOREBAY. NOTE ALL WATER FLOWING THROUGH FOREBAY AND OUT EITHER TAILRACE OR SLUICE GATE (INSTEAD OF OVER DAM) BECAUSE OF LOW WATER FLOW. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files, Dam No. 5 listing - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  18. 49. Photocopy of photograph, October 22, 1933. VIEW OF POWER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    49. Photocopy of photograph, October 22, 1933. VIEW OF POWER HOUSE, FOREBAY AND RIVER. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files, Dam No. 5 listing) - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  19. 50. Photocopy of photograph, April 27, 1937. VIEW OF POWER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    50. Photocopy of photograph, April 27, 1937. VIEW OF POWER HOUSE AND SUBSTATION DURING FLOOD. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files, Dam No. 5 listing) - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  20. 58. Photocopy of photograph, no date. VIEW OF GENERATOR UNIT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    58. Photocopy of photograph, no date. VIEW OF GENERATOR UNIT 2. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files, Properties-Buildings and Equipment listing) - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV