Science.gov

Sample records for a4-a parkersburg wv

  1. 75 FR 26793 - Fypon, Ltd., Parkersburg, WV, Including Workers Whose Unemployment Insurance, (UI) Wages Are Paid...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-12

    ...] Fypon, Ltd., Parkersburg, WV, Including Workers Whose Unemployment Insurance, (UI) Wages Are Paid..., Including Workers Whose Unemployment Insurance, (UI) Wages Are Paid Through Therma-Tru Doors, Archbold, OH... reported under a separate unemployment insurance (UI) tax account under the name Therma-Tru Doors...

  2. 2. VIEW EAST, REAR. see also WV2371, WV2372, WV2373, WV23710, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. VIEW EAST, REAR. see also WV-237-1, WV-237-2, WV-237-3, WV-237-10, WV-237-F-2, WV-237-G-3 and historic photographs WV-237-11, WV-237-12, WV-237-13, WV-237-14, WV-237-18, WV-237-F-5) - Parsons Nursery, Original Wash House, South side of U.S. Route 219, Parsons, Tucker County, WV

  3. 40 CFR 81.70 - Parkersburg (West Virginia)-Marietta (Ohio) Interstate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Parkersburg (West Virginia)-Marietta... PLANNING PURPOSES Designation of Air Quality Control Regions § 81.70 Parkersburg (West Virginia)-Marietta (Ohio) Interstate Air Quality Control Region. The Parkersburg (West Virginia)-Marietta (Ohio) Interstate...

  4. 40 CFR 81.70 - Parkersburg (West Virginia)-Marietta (Ohio) Interstate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (Ohio) Interstate Air Quality Control Region. 81.70 Section 81.70 Protection of Environment... (Ohio) Interstate Air Quality Control Region. The Parkersburg (West Virginia)-Marietta (Ohio) Interstate... County, Tyler County, Wetzel County, Wood County. In the State of Ohio: Athens County, Meigs...

  5. Greening America's Capitals - Charleston, WV

    EPA Pesticide Factsheets

    This Greening America’s Capitals report outlines design concepts that could improve Slack Plaza in Charleston, WV, by creating more opportunities for local businesses, better managing stormwater runoff, and increasing green space.

  6. 1. Photocopied January 1973 from the Keystone Bridge Company Album, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Photocopied January 1973 from the Keystone Bridge Company Album, 1874. THE KEYSTONE BRIDGE COMPANY: LUCY FURNACE. - Baltimore & Ohio Railroad, Parkersburg Bridge, Ohio River, Parkersburg, Wood County, WV

  7. RadNet Air Data From Charleston, WV

    EPA Pesticide Factsheets

    This page presents radiation air monitoring and air filter analysis data for Charleston, WV from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

  8. 76 FR 28312 - Safety Zones; Fireworks Display Kanawha River, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zones; Fireworks Display Kanawha River, WV AGENCY... protect persons and vessels from the potential safety hazards associated with annual firework displays... movement of vessels within the established fireworks display areas. Entry into, transit through,...

  9. 77 FR 17561 - West Virginia Disaster #WV-00023

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-26

    ... ADMINISTRATION West Virginia Disaster WV-00023 AGENCY: Small Business Administration. ACTION: Notice. SUMMARY: This is a Notice of the Presidential declaration of a major disaster for the State of West Virginia..., Marion, Wayne. Contiguous Counties (Economic Injury Loans Only): West Virginia: Boone, Cabell, Harrison...

  10. 77 FR 45410 - West Virginia Disaster #WV-00028

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-31

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION West Virginia Disaster WV-00028 AGENCY: U.S. Small Business Administration. ACTION: Notice... for the State of West Virginia (FEMA--4071--DR), dated 07/23/2012. Incident: Severe Storms and...

  11. 78 FR 55770 - West Virginia Disaster #WV-00032

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-11

    ... ADMINISTRATION West Virginia Disaster WV-00032 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of West Virginia... adversely affected by the disaster: Primary Counties: Roane. Contiguous Counties: West Virginia: Calhoun...

  12. 77 FR 55890 - West Virginia Disaster Number WV-00028

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-11

    ... ADMINISTRATION West Virginia Disaster Number WV-00028 AGENCY: U.S. Small Business Administration. ACTION... Assistance Only for the State of West Virginia (FEMA--4071--DR), dated 07/23/2012. Incident: Severe Storms... disaster declaration for Private Non-Profit organizations in the State of West Virginia, dated 07/23/2012...

  13. 77 FR 25224 - West Virginia Disaster Number WV-00023

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-27

    ... ADMINISTRATION West Virginia Disaster Number WV-00023 AGENCY: U.S. Small Business Administration. ACTION... of West Virginia (FEMA-4059-DR), dated 03/ 16/2012. Incident: Severe Storms, Tornadoes, Flooding... State of WEST VIRGINIA, dated 03/16/2012 is hereby amended to include the following areas as adversely...

  14. 75 FR 17177 - West Virginia Disaster #WV-00016

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-05

    ... ADMINISTRATION West Virginia Disaster WV-00016 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a Notice of the Presidential declaration of a major disaster for the State of West..., Kanawha, Mercer, Raleigh. Contiguous Counties (Economic Injury Loans Only): West Virginia: Boone, Clay...

  15. 75 FR 38155 - West Virginia Disaster #WV-00020

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-01

    ... ADMINISTRATION West Virginia Disaster WV-00020 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a Notice of the Presidential declaration of a major disaster for the State of WEST...Dowell, Mingo, Wyoming. Contiguous Counties (Economic Injury Loans Only): West Virginia: Boone, Lincoln...

  16. 75 FR 41246 - West Virginia Disaster Number WV-00020

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-15

    ... ADMINISTRATION West Virginia Disaster Number WV-00020 AGENCY: U.S. Small Business Administration. ACTION... of West Virginia (FEMA-1918-DR), dated 06/ 24/2010. Incident: Severe storms, flooding, mudslides, and... West Virginia, dated 06/24/2010 is hereby amended to include the following areas as adversely affected...

  17. 75 FR 20401 - West Virginia Disaster Number WV-00017

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-19

    ... ADMINISTRATION West Virginia Disaster Number WV-00017 AGENCY: U.S. Small Business Administration. ACTION... Assistance Only for the State of West Virginia (FEMA-1893-DR), dated 03/29/2010. Incident: Severe Storms... major disaster declaration for Private Non-Profit organizations in the State of West Virginia, dated 03...

  18. 77 FR 25225 - West Virginia Disaster Number WV-00027

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-27

    ... ADMINISTRATION West Virginia Disaster Number WV-00027 AGENCY: U.S. Small Business Administration. ACTION... of West Virginia (FEMA--4061--DR), dated 03/22/2012. Incident: Severe storms, flooding, mudslides and... West Virginia, dated 03/22/2012 is hereby amended to include the following areas as adversely affected...

  19. 75 FR 38155 - West Virginia Disaster #WV-00021

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-01

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION West Virginia Disaster WV-00021 AGENCY: U.S. Small Business Administration. ACTION: Notice... for the State of WEST VIRGINIA (FEMA-1918-DR), dated 06/24/2010. Incident: Severe Storms, Flooding...

  20. 77 FR 20475 - West Virginia Disaster #WV-00025

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-04

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION West Virginia Disaster WV-00025 AGENCY: U.S. Small Business Administration. ACTION: Notice... for the State of West Virginia (FEMA-4061-DR), dated 03/22/2012. Incident: Severe Storms, Flooding...

  1. 77 FR 47908 - West Virginia Disaster Number WV-00028

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-10

    ... ADMINISTRATION West Virginia Disaster Number WV-00028 AGENCY: U.S. Small Business Administration. ACTION... Assistance Only for the State of West Virginia (FEMA-4071-DR), dated 07/23/2012. Incident: Severe Storms and... disaster declaration for Private Non-Profit organizations in the State of West Virginia, dated 07/23/2012...

  2. 78 FR 48537 - West Virginia Disaster # WV-00033

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-08

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION West Virginia Disaster WV-00033 AGENCY: U.S. Small Business Administration. ACTION: Notice... for the State of West Virginia (FEMA-4132-DR), dated 07/26/2013. Incident: Severe Storms and Flooding...

  3. 75 FR 24756 - West Virginia Disaster Number WV-00017

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-05

    ... ADMINISTRATION West Virginia Disaster Number WV-00017 AGENCY: U.S. Small Business Administration. ACTION... Assistance Only for the State of West Virginia (FEMA--1893--DR), dated 03/29/2010. Incident: Severe Storms... major disaster declaration for Private Non-Profit organizations in the State of West Virginia, dated 03...

  4. 77 FR 23538 - West Virginia Disaster Number WV-00025

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-19

    ... ADMINISTRATION West Virginia Disaster Number WV-00025 AGENCY: U.S. Small Business Administration. ACTION... Assistance Only for the State of West Virginia (FEMA-4061-DR), dated 03/22/2012. Incident: Severe storms... major disaster declaration for Private Non-Profit organizations in the State of WEST VIRGINIA, dated 03...

  5. 75 FR 20400 - West Virginia Disaster Number WV-00016

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-19

    ... ADMINISTRATION West Virginia Disaster Number WV-00016 AGENCY: U.S. Small Business Administration. ACTION... of West Virginia (FEMA-1893-DR), dated 03/ 29/2010. Incident: Severe Storms, Flooding, Mudslides, and... the State of West Virginia, dated 03/29/2010 is hereby amended to establish the incident period for...

  6. 75 FR 41246 - West Virginia Disaster Number WV-00021

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-15

    ... ADMINISTRATION West Virginia Disaster Number WV-00021 AGENCY: U.S. Small Business Administration. ACTION... Assistance Only for the State of West Virginia (FEMA-1918-DR), dated 06/24/2010. Incident: Severe storms... major disaster declaration for Private Non-Profit organizations in the State of West Virginia, dated 06...

  7. 77 FR 70204 - West Virginia; Disaster Number WV-00029

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-23

    ... ADMINISTRATION West Virginia; Disaster Number WV-00029 AGENCY: U.S. Small Business Administration. ACTION... of West Virginia (FEMA-4071-DR), dated 09/ 19/2012. Incident: Severe Storms and Straight-line Winds.... SUPPLEMENTARY INFORMATION: The notice of the Presidential disaster declaration for the State of West Virginia...

  8. 77 FR 23538 - West Virginia Disaster Number WV-00027

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-19

    ... ADMINISTRATION West Virginia Disaster Number WV-00027 AGENCY: U.S. Small Business Administration. ACTION... of West Virginia (FEMA-4061-DR), dated 03/ 22/2012. Incident: Severe Storms, Flooding, Mudslides, and... of West Virginia, dated 03/22/2012 is hereby amended to establish the incident period for this...

  9. 77 FR 73510 - West Virginia; Disaster #WV-00031

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-10

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION West Virginia; Disaster WV-00031 AGENCY: U.S. Small Business Administration. ACTION: Notice... for the State of West Virginia (FEMA-4093-DR), dated 11/27/2012. Incident: Hurricane Sandy. Incident...

  10. 75 FR 17176 - West Virginia Disaster #WV-00017

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-05

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION West Virginia Disaster WV-00017 AGENCY: U.S. Small Business Administration. ACTION: Notice... for the State of West Virginia (FEMA-1893-DR), dated 03/29/2010. Incident: Severe Storms, Flooding...

  11. 78 FR 14148 - West Virginia Disaster #WV-00030

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-04

    ... ADMINISTRATION West Virginia Disaster WV-00030 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of West Virginia... adversely affected by the disaster: Primary Counties: Nicholas. Contiguous Counties: West Virginia: Braxton...

  12. 77 FR 60002 - West Virginia Disaster #WV-00029

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-01

    ... ADMINISTRATION West Virginia Disaster WV-00029 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a Notice of the Presidential declaration of a major disaster for the State of West...; Nicholas; Raleigh. Contiguous Counties (Economic Injury Loans Only): West Virginia: Boone; Braxton; Clay...

  13. 77 FR 19405 - West Virginia Disaster #WV-00027

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-30

    ... ADMINISTRATION West Virginia Disaster WV-00027 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a Notice of the Presidential declaration of a major disaster for the State of West... Counties (Economic Injury Loans Only): West Virginia: Boone, Lincoln, Mingo, Wyoming. The Interest Rates...

  14. 77 FR 71667 - West Virginia Disaster Number WV-00029

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-03

    ... ADMINISTRATION West Virginia Disaster Number WV-00029 AGENCY: U.S. Small Business Administration. ACTION... of West Virginia (FEMA-4071-DR), dated 09/ 19/2012. Incident: Severe storms and straight-line winds.... SUPPLEMENTARY INFORMATION: The notice of the President's major disaster declaration for the State of West...

  15. 75 FR 35103 - West Virginia Disaster Number WV-00015

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-21

    ... ADMINISTRATION West Virginia Disaster Number WV-00015 AGENCY: Small Business Administration. ACTION: Amendment 1... Only for the State of West Virginia (FEMA-1881-DR), dated 03/02/2010. Incident: Severe winter storm and... Private Non-Profit organizations in the State of West Virginia, dated 03/02/2010, is hereby amended to...

  16. 75 FR 41246 - West Virginia Disaster Number WV-00020

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-15

    ... ADMINISTRATION West Virginia Disaster Number WV-00020 AGENCY: U.S. Small Business Administration. ACTION... of West Virginia (FEMA-1918-DR), dated 06/24/2010. Incident: Severe storms, flooding, mudslides, and... of West Virginia, dated 06/24/2010 is hereby amended to establish the incident period for this...

  17. 75 FR 41245 - West Virginia Disaster Number WV-00018

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-15

    ... ADMINISTRATION West Virginia Disaster Number WV-00018 AGENCY: U.S. Small Business Administration. ACTION... Assistance Only for the State of WEST VIRGINIA (FEMA-1903-DR), dated 04/23/2010. Incident: Severe Winter... disaster declaration for Private Non-Profit organizations in the State of WEST VIRGINIA, dated 04/23/2010...

  18. 75 FR 11582 - West Virginia Disaster # WV-00015

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-11

    ... From the Federal Register Online via the Government Publishing Office ] SMALL BUSINESS ADMINISTRATION West Virginia Disaster WV-00015 AGENCY: U.S. Small Business Administration. ACTION: Notice... for the state of West Virginia (FEMA-1881-DR), dated 03/02/2010. Incident: Severe winter storm and...

  19. 76 FR 71936 - Upper Deckers Creek Watershed, Preston County, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-21

    ... Natural Resources Conservation Service Upper Deckers Creek Watershed, Preston County, WV AGENCY: Natural... Environmental Quality Guidelines (40 CFR part 1500); and the Natural Resources Conservation Service Guidelines (7 CFR part 650); the Natural Resources Conservation Service, U. S. Department of Agriculture,...

  20. METEOSAT IR and WV channels Fundamental Climate Data Record

    NASA Astrophysics Data System (ADS)

    Roebeling, Rob; John, Viju; Hewison, Tim; Lattanzio, Alessio; Schulz, Joerg

    2015-04-01

    The detection of climate change and analysis of climate variability at inter-annual scales requires long-term, well calibrated observations that are homogenised in time and space. Observations from EUMETSAT's series of Meteosat First Generation (MFG) and Meteosat Second Generation (MSG) geostationary satellites span a period from 1982 to today. Although these satellites provide data for climate analysis at multi-decadal scales, their applicability for such analysis is hampered by heterogeneities in the time series due to successive radiometers having different filter functions and changes in the calibration methodology. EUMETSAT initiated the activity to improve the quality of these data, and generates a Fundamental Climate Data Record (FCDR) of Water Vapour (WV) and Infrared (IR) channel radiances, i.e., a long-term data record of calibrated and quality-controlled sensor data designed to allow the generation of homogeneous products that are accurate and stable enough for climate monitoring. The generation of this FCDR is part of EUMETSATs activities in the European Re-Analysis of global CLIMate observations 2 (ERA-CLIM2) project. We present a method to inter-calibrate the complete time series of WV (6.3 µm) and IR (11.8 µm) channel radiances from MFG-MVIRI and MSG-SEVIRI observations. Our method is based on the principles of the Global Space-based Inter-Calibration System (GSICS). A systematic review of spectral conversion functions, which often dominate the errors, indicates that spectral changes of the WV channel from HIRS/2 to HIRS/3 triples the uncertainty of inter-calibrated METEOSAT WV radiances. We will show that these issues can be circumvented by using HIRS/2, AIRS, and IASI as reference instruments, and thus keeping the uncertainties due to spectral conversion similar throughout the time series. Finally we will present an evaluation of 30 years of recalibrated HIRS, MVIRI and /SEVIRI radiances from the IR and WV channels, and demonstrate their improved

  1. 75 FR 65251 - Proposed Amendment of Class E Airspace; Charleston, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-22

    ... examined during normal business hours at the office of the Eastern Service Center, Federal Aviation... more above the surface of the earth. * * * * * AEA WV E5 Charleston, WV Yeager Airport, Charleston,...

  2. 77 FR 13176 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-05

    .... ADDRESSES: Direct all written comments to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to make comments online is also... copies should be directed to Bruce A. Sharp, Bureau of the Public Debt, 200 Third Street A4-A...

  3. 77 FR 38394 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-27

    ... consideration. ADDRESSES: Direct all written comments to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to make comments... information or copies should be directed to Bruce A. Sharp, Bureau of the Public Debt, 200 Third Street A4-A...

  4. 77 FR 19424 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-30

    ...: Direct all written comments to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to make comments online is also... copies should be directed to Bruce A. Sharp, Bureau of the Public Debt, 200 Third Street A4-A...

  5. Perceptions of oral health by the WV community.

    PubMed

    Veselicky, Louise T; Sharps, Gina; Veselicky, Kenneth A

    2013-01-01

    This survey was undertaken to establish baseline measurements in regards to the oral health beliefs and practices of the general public throughout West Virginia as a starting point to create an effective educational initiative fostering oral health as an integral component of health. A population based 37 item telephonic opinion survey on a representative sample of WV state wide residents was conducted to understand practices, habits and experiences with oral health, to identify barriers to oral health, and determine the perception of its importance to other health conditions. West Virginians rank obesity as the most serious health problem and dental health a significantly less serious concern. Half admitted to less than good dental health. Cost was most commonly cited for not accessing oral care. A unified health promotion message among all health care providers is vital if general health of West Virginia citizens is to be improved. The links between oral health, coronary artery disease, diabetes, and pulmonary conditions can be used as a common starting point to embrace health advancement in general with the ultimate goal of changing current attitudes and practices and develop sustainable health programs that result in positive oral health/overall health in individuals and communities.

  6. 77 FR 13175 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-05

    ..., Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The...: Requests for additional information or copies should be directed to Bruce A. Sharp, Bureau of the Public... provide information. Dated: February 28, 2012. Bruce A. Sharp, Bureau Clearance Officer. BILLING CODE 4810...

  7. 77 FR 65247 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-25

    ... consideration. ADDRESSES: Direct all written comments to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or bruce.sharp@bpd.treas.gov . The opportunity to make comments... additional information or copies should be directed to Bruce A. Sharp, Bureau of the Public Debt, 200 Third...

  8. 33 CFR 165.822 - Safety Zone; Fireworks Display, Kanawha River, WV.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Safety Zone; Fireworks Display... Safety Zone; Fireworks Display, Kanawha River, WV. (a) Safety zones. The following areas are designated... Virginia Special Olympics Fireworks Display Between mile 57.9 and 58.9, Charlestown, WV First Friday...

  9. 33 CFR 165.822 - Safety Zone; Fireworks Display, Kanawha River, WV.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Safety Zone; Fireworks Display... Safety Zone; Fireworks Display, Kanawha River, WV. (a) Safety zones. The following areas are designated... Virginia Special Olympics Fireworks Display Between mile 57.9 and 58.9, Charlestown, WV First Friday...

  10. 33 CFR 165.822 - Safety Zone; Fireworks Display, Kanawha River, WV.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Safety Zone; Fireworks Display... Safety Zone; Fireworks Display, Kanawha River, WV. (a) Safety zones. The following areas are designated... Virginia Special Olympics Fireworks Display Between mile 57.9 and 58.9, Charlestown, WV First Friday...

  11. 33 CFR 165.822 - Safety Zone; Fireworks Display, Kanawha River, WV.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Safety Zone; Fireworks Display... Safety Zone; Fireworks Display, Kanawha River, WV. (a) Safety zones. The following areas are designated... Virginia Special Olympics Fireworks Display Between mile 57.9 and 58.9, Charlestown, WV First Friday...

  12. 75 FR 63540 - Request for Public Comment, Morgantown Municipal Airport, Morgantown, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Request for Public Comment, Morgantown Municipal Airport, Morgantown, WV... land currently owned by the City of Morgantown, Sponsor for the Morgantown Municipal Airport...

  13. 76 FR 7584 - Matthews International Corporation, Bronze Division, Kingwood, WV; Notice of Affirmative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-10

    ... Employment and Training Administration Matthews International Corporation, Bronze Division, Kingwood, WV... workers and former workers of Matthews International Corporation, Bronze Division, Kingwood, West Virginia... activities related to the production of bronze burial markers and memorial products. In the request...

  14. 75 FR 55612 - TRG Insurance Solutions, LLC; Beckley, WV; Notice of Affirmative Determination Regarding...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF LABOR Employment and Training Administration TRG Insurance Solutions, LLC; Beckley, WV; Notice of Affirmative... Solutions, LLC, Beckley, West Virginia (subject firm). The negative determination was issued on July...

  15. Efficacy of a topical application of Certifect® (fipronil 6.26% w/v, amitraz 7.48% w/v, (S)-methoprene 5.63% w/v) for the treatment of canine generalized demodicosis

    PubMed Central

    Fourie, Josephus; Dumont, Pascal; Halos, Lénaïg; Beugnet, Frederic; Pollmeier, Matthias

    2013-01-01

    The efficacy of the treatment with Certifect ® (containing fipronil 6.26% w/v, amitraz 7.48% w/v, (S)-methoprene 5.63% w/v) applied topically was assessed in 18 dogs diagnosed with clinical generalized demodicosis. Three treatment regimens were compared over a 3-month period. Starting at Day 0, dogs were treated monthly (group 1) or every two weeks (group 2) with the combination of fipronil, amitraz, and (S)-methoprene or with monthly topical applications of the combination of amitraz and metaflumizone (group 3, reference treatment). Clinical examinations including deep skin scrapings were performed every month in order to evaluate the resolution of clinical signs and the reduction in mite counts. On Day 84, the percentage reduction of mite counts in group 1 was 99.8%, whereas no Demodex canis could be detected in groups 2 and 3 (i.e. 100% parasitological efficacy). As a result of the Demodex mite count reduction, the skin condition of the dogs improved significantly in all groups. This study illustrates, that both monthly and bi-weekly treatments with Certifect were effective in treating dogs with generalized demodicosis over a 3-month period. PMID:24256940

  16. Downregulation of Fas activity rescues early onset of diabetes in c-Kit(Wv/+) mice.

    PubMed

    Feng, Zhi-Chao; Riopel, Matthew; Li, Jinming; Donnelly, Lisa; Wang, Rennian

    2013-03-15

    c-Kit and its ligand stem cell factor (SCF) are important for β-cell survival and maturation; meanwhile, interactions between the Fas receptor (Fas) and Fas ligand are capable of triggering β-cell apoptosis. Disruption of c-Kit signaling leads to severe loss of β-cell mass and function with upregulation of Fas expression in c-Kit(Wv/+) mouse islets, suggesting that there is a critical balance between c-Kit and Fas activation in β-cells. In the present study, we investigated the interrelationship between c-Kit and Fas activation that mediates β-cell survival and function. We generated double mutant, c-Kit(Wv/+);Fas(lpr/lpr) (Wv(-/-)), mice to study the physiological and functional role of Fas with respect to β-cell function in c-Kit(Wv/+) mice. Isolated islets from these mice and the INS-1 cell line were used. We observed that islets in c-Kit(Wv/+) mice showed a significant increase in β-cell apoptosis along with upregulated p53 and Fas expression. These results were verified in vitro in INS-1 cells treated with SCF or c-Kit siRNA combined with a p53 inhibitor and Fas siRNA. In vivo, Wv(-/-) mice displayed improved β-cell function, with significantly enhanced insulin secretion and increased β-cell mass and proliferation compared with Wv(+/+) mice. This improvement was associated with downregulation of the Fas-mediated caspase-dependent apoptotic pathway and upregulation of the cFlip/NF-κB pathway. These findings demonstrate that a balance between the c-Kit and Fas signaling pathways is critical in the regulation of β-cell survival and function.

  17. Effect of ultraviolet irradiation on mast cell-deficient W/Wv mice

    SciTech Connect

    Ikai, K.; Danno, K.; Horio, T.; Narumiya, S.

    1985-07-01

    The effect of UV irradiation on the skin was investigated in (WB-W/+) X (C57BL/6J-Wv/+)F1-W/Wv mice, which are genetically deficient in tissue mast cells. Their congenic littermates (+/+) and normal albino mice (ICR or BALB/c) were used as controls. Mice were irradiated with 500 mJ/cm2 of UVB and the increment of ear thickness was measured before and 6, 12, and 24 h after irradiation. Ear swelling in W/Wv mice at 12 and 24 h after irradiation was significantly smaller than that in +/+ and ICR mice. In contrast, the number of sunburn cells formed 24 h after UVB irradiation (200 or 500 mJ/cm2) was similar in W/Wv, +/+ and ICR mice. On the other hand, when mice were treated with 8-methoxy-psoralen (0.5%) plus UVA irradiation (4 J/cm2) (topical PUVA), ears of W/Wv and BALB/c mice, which were both white in color, were thickened similarly 72 h after treatment, but less swelling was observed in +/+ mice, which were black in skin color. The amount of prostaglandin D2 (PGD2) in ears, determined by radioimmunoassay specific for PGD2, was elevated 3-fold in +/+ and ICR mice at 3 h after irradiation with 500 mJ/cm2 of UVB in comparison with basal level without irradiation. However, such elevation was not observed in W/Wv mice. These results suggest that mast cells play an important role in UVB-induced inflammation, and PGs from mast cells are responsible at least in part for the development of this reaction. However, neither mast cells nor PGs contribute to the sunburn cell formation and ear swelling response by PUVA treatment.

  18. 75 FR 65525 - TRG Insurance Solutions, Beckley, WV; Notice of Revised Determination on Reconsideration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-25

    ... Employment and Training Administration TRG Insurance Solutions, Beckley, WV; Notice of Revised Determination... of TRG Insurance Solutions, Beckley, West Virginia, to apply for Trade Adjustment Assistance. On... determine that workers of TRG Insurance Solutions, Beckley, West Virginia, who are engaged in...

  19. Fabrication and characterization of MCC approved testing material: ATM-WV/205 glass

    SciTech Connect

    Maupin, G.D.; Bowen, W.M.; Daniel, J.L.

    1988-08-01

    The ATM-WV/205 glass was produced in accordance with PNL's QA Manual for License-Related Programs, MCC technical procedures, and MCC QA Plan that were in effect during the course of this work. The method and procedure to be used in the fabrication and characterization of the ATM-WV/205 glass were specified in two run plans for glass preparation and a characterization plan. The ATM-WV/205 glass meets all specifications. The elemental composition and oxidation state of the glass are within the sponsor's specifications. Visually, the ATM-WV/205 glass bars appear uniformly glassy and generally without exterior features. Microscopic examination and x-ray diffraction revealed low (about 0.5 wt %) concentrations of 3-..mu..m iron chrome spinel crystals and 1-..mu..m ruthenium inclusions scattered randomly throughout the glassy matrix. Closed porosity, with pores ranging in diameter from 20 to 135 ..mu..m, was observed in all samples. 3 refs., 10 figs., 21 tabs.

  20. 16. Photocopy of published illustration, 1885; W.V. Herancourt, illustrator; J. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. Photocopy of published illustration, 1885; W.V. Herancourt, illustrator; J. Monash, Minneapolis, publisher; SHOWS BIRDS-EYE VIEW OF DOWNTOWN MINNEAPOLIS WITH MILWAUKEE ROAD FREIGHT HOUSE LOCATED 2 INCHES FROM TOP AND LEFT MARGINS; LOOKING NORTHWEST - Chicago, Milwaukee, St. Paul & Pacific Railroad Freighthouse, 201-211 Third Avenue South, Minneapolis, Hennepin County, MN

  1. 75 FR 56469 - Safety Zone; Ohio River, Wheeling, WV, Wheeling Heritage Port Sternwheel Foundation Fireworks...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-16

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Ohio River, Wheeling, WV, Wheeling Heritage... Ohio River extending the full width of the river. The safety zone is needed to protect spectators and... Marker 90.5 on the Ohio River extending the full width of the river. The safety zone is needed to...

  2. Exploring Climate Science with WV Educators: A Regional Model for Teacher Professional Development

    NASA Astrophysics Data System (ADS)

    Ruberg, L. F.; Calinger, M.

    2014-12-01

    The National Research Council Framework for K-12 Science Literacy reports that children reared in rural agricultural communities, who experience regular interactions with plants and animals, develop more sophisticated understanding of ecology and biological systems than do urban and suburban children of the same age. West Virginia (WV) is a rural state. The majority of its residents live in communities of fewer than 2,500 people. Based on the features of the population being served and their unique strengths, this presentation focuses on a regional model for teacher professional development that addresses agricultural and energy vulnerabilities and adaptations to climate change in WV. The professional development model outlined shows how to guide teachers to use a problem-based learning approach to introduce climate data and analysis techniques within a scenario context that is locally meaningful. This strategy engages student interest by focusing on regional and community concerns. Climate science standards are emphasized in the Next Generation Science Standards, but WV has not provided its teachers with appropriate instructional resources to meet those standards. The authors addressed this need by offering a series of climate science education workshops followed by online webinars offered to WV science educators free of charge with funding by the West Virginia Space Grant Consortium. The authors report on findings from this series of professional development workshops conducted in partnership with the West Virginia Science Teachers Association. The goal was to enhance grades 5-12 teaching and learning about climate change through problem-based learning. Prior to offering the climate workshops, all WV science educators were asked to complete a short questionnaire. As Figure 1 shows, over 40% of the teacher respondents reported being confident in teaching climate science content. For comparison post workshops surveys measure teacher confidence in climate science

  3. 76 FR 75464 - Approval and Promulgation of Air Quality Implementation Plans; West Virginia and Ohio...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-02

    ... Ohio; Determinations of Attainment of the 1997 Annual Fine Particle Standard for the Parkersburg... particle (PM 2.5 ) nonattainment area and the Wheeling, WV-OH PM 2.5 nonattainment ] area (hereafter... Parkersburg-Marietta, WV- OH and Wheeling, WV-OH fine particle (PM 2.5 ) nonattainment areas attained the 1997...

  4. Changes in neuromuscular transmission in the W/Wv mouse internal anal sphincter

    PubMed Central

    Duffy, AM; Cobine, CA; Keef, KD

    2011-01-01

    Background Intramuscular interstitial cells of Cajal (ICC-IM) have been shown to participate in nitrergic neuromuscular transmission (NMT) in various regions of the gastrointestinal (GI) tract but their role in the internal anal sphincter (IAS) is still uncertain. Contractile studies of the IAS in the W/Wv mouse (a model in which ICC-IM numbers are markedly reduced) have reported that nitrergic NMT persists and that ICC-IM are not required. However, neither the changes in electrical events underlying NMT nor the contributions of other non-nitrergic neural pathways have been examined in this model. Methods The role of ICC-IM in NMT was examined by recording the contractile and electrical events associated with electrical field stimulation (EFS) of motor neurons in the IAS of wildtype and W/Wv mice. Nitrergic, purinergic and cholinergic components were identified using inhibitors of these pathways. Key Results Under NANC conditions, purinergic, and nitrergic pathways both contribute to EFS induced inhibitory junction potentials (IJPs) and relaxation. Purinergic IJPs and relaxation were intact in the W/Wv mouse IAS whereas nitrergic IJPs were reduced by 50–60% while relaxation persisted. In the presence of L-NNA (NOS inhibitor) and MRS2500 (P2Y1 receptor antagonist), EFS gave rise to cholinergic depolarization and contractions that were abolished by atropine. Cholinergic depolarization was absent in the W/Wv mouse IAS while contraction persisted. Conclusions and Inferences ICC-IM significantly contribute to the electrical events underlying nitrergic and cholinergic NMT whereas contractile events persist in the absence of ICC-IM. The purinergic inhibitory neural pathway appears to be independent of ICC-IM. PMID:22074497

  5. 76 FR 43634 - Approval and Promulgation of Air Quality Implementation Plans; West Virginia and Ohio...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-21

    ... Ohio; Determinations of Attainment of the 1997 Annual Fine Particle Standard for the Parkersburg...-Ohio (WV-OH) nonattainment area and the Wheeling, WV-OH fine particle (PM 2.5 ) nonattainment areas...

  6. 7. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1880's. VOLCANO LITTLE THEATRE GUILD. SOME CAST. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  7. 19. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. THE OLD STILES HOUSE, LOOKING WEST. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  8. 9. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. VIEW LOOKING NORTH. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  9. 16. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. STILES RESIDENCE, THORNHILL FARM. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  10. 17. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. THE OLD STILES HOUSE LOOKING EAST. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  11. 5. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1880. VOLCANO TOWN HALL. BLACKLIN HOUSE AT LEFT. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  12. 1. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. VIEW LOOKING SOUTH. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  13. 14. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. MOUNT FARM OIL COMPANY. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  14. 12. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. THORNHILL STORE. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  15. 78 FR 72880 - Adequacy Status of the West Virginia Portion of the Steubenville-Weirton, WV-OH Nonattainment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-04

    ... findings through the transportation conformity adequacy process, under the Clean Air Act (CAA), for... of the Steubenville- Weirton, WV-OH 1997 PM 2.5 national ambient air quality standard (NAAQS... annual PM 2.5 air quality standard. DATES: Effective on December 19, 2013. FOR FURTHER...

  16. 78 FR 72881 - Adequacy Status of the West Virginia Portion of the Steubenville-Weirton, WV-OH Nonattainment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-04

    ... findings through the transportation conformity adequacy process, under the Clean Air Act (CAA), for... of the Steubenville- Weirton, WV-OH 2006 PM 2.5 national ambient air quality standard (NAAQS... 2006 daily PM 2.5 air quality standard. DATES: Effective on December 19, 2013. FOR FURTHER...

  17. Higher Susceptibility of Mast-Cell-Deficient W/WV Mutant Mice to Brain Thromboembolism and Mortality Caused by Intravenous Injection of India Ink

    PubMed Central

    Kitamura, Y.; Taguchi, T.; Yokoyama, M.; Inoue, M.; Yamatodani, A.; Asano, H.; Koyama, T.; Kanamaru, A.; Hatanaka, K.; Wershil, B. K.; Galli, S. J.

    1986-01-01

    (WB × C57BL/6)F1-W/Wv mice possess a genetic defect in multipotential hematopoietic stem cells; the mice are anemic and lack mast cells. The authors injected diluted India ink intravenously into W/WV mice and congenic normal +/+ mice and searched for genetically determined differences in the development of complications of the injection. In both W/WV and +/+ mice, intravenous ink resulted in thrombocytopenia and markedly prolonged bleeding times, as well as prolonged partial thromboplastin and prothrombin times and reduced fibrinogen concentrations. These effects were similar in W/WV and +/+ mice, although the reduction in platelet counts was greater in W/WV mice. In addition, the mortality associated with ink injection was significantly higher in W/WV mice than in congenic +/+ mice. Most W/WV mice which died first exhibited paralysis, and examination under the dissection microscope revealed that ink injection resulted in significantly more cerebral thromboemboli in W/WV mice than in +/+ controls. Bone marrow transplantation from +/+ mice corrected both the mast cell deficiency and the anemia of W/WV mice and protected the W/WV recipients from the adverse consequences of ink injection. By contrast, +/+ mice rendered as anemic as W/WV mice by breeding did not exhibit increased morbidity and mortality after ink injection. (WC × C57BL/6)F1-S1/S1d mice, which are anemic and lack mast cells because of a genetic defect different from that of W/WV mice, also exhibited increased morbidity and mortality after intravenous ink. Finally, mixture of ink with commercial heparin prior to intravenous injection markedly reduced the incidence of cerebral thromboembolism and death in W/WV mice. Taken together, these findings suggest that the increased morbidity and mortality exhibited by W/WV and S1/S1d mice that received injected ink might be related to their mast cell deficiency rather than to their anemia. But measurement of the histamine content of the blood and various tissues

  18. 75 FR 47715 - Safety Zone; Kanawha River Mile 56.7 to 57.6, Charleston, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-09

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Kanawha River Mile 56.7 to 57.6, Charleston... at mile 57.6 (Interstate Route 64 Bridge), extending the entire width of the river. This safety zone... held on the Kanawha River in Charleston, WV at mile 57.6-57.6. The Coast guard believes a safety zone...

  19. Cross-language specialization in phonetic processing: English and Hindi perception of /w/-/v/ speech and nonspeech.

    PubMed

    Iverson, Paul; Wagner, Anita; Pinet, Melanie; Rosen, Stuart

    2011-11-01

    This study examined the perceptual specialization for native-language speech sounds, by comparing native Hindi and English speakers in their perception of a graded set of English /w/-/v/ stimuli that varied in similarity to natural speech. The results demonstrated that language experience does not affect general auditory processes for these types of sounds; there were strong cross-language differences for speech stimuli, and none for stimuli that were nonspeech. However, the cross-language differences extended into a gray area of speech-like stimuli that were difficult to classify, suggesting that the specialization occurred in phonetic processing prior to categorization.

  20. Interleukin 3 perfusion in W/Wv mice allows the development of macroscopic hematopoietic spleen colonies and restores cutaneous mast cell number

    SciTech Connect

    Ody, C.; Kindler, V.; Vassalli, P. )

    1990-07-01

    The genetically anemic W/Wv mice are characterized by the inability of their bone marrow cells to form macroscopic pluripotent hematopoietic colonies in the spleen of irradiated recipients upon transfer (colony-forming units). Furthermore, they almost totally lack mast cells, notably in the skin. In the present study, we have tested the effect of recombinant murine interleukin 3 (rmIL-3) on W/Wv mice hematopoiesis. Transfer of W/Wv bone marrow cells into lethally irradiated recipients perfused with rmIL-3 is followed by the appearance of macroscopic spleen colonies. Moreover, perfusion of rmIL-3 in W/Wv mice: (a) restores almost normal total numbers of hematopoietic precursors (colony-forming cells), but without modification of anemia; and (b) leads to the appearance of a normal number of mastocytes in the skin.

  1. Bile reflux due to disturbed gastric movement is a cause of spontaneous gastric ulcer in W/Wv mice.

    PubMed

    Azuma, T; Dojyo, M; Ito, S; Yamazaki, Y; Miyaji, H; Ito, Y; Suto, H; Kuriyama, M; Kato, T; Kohli, Y

    1999-06-01

    c-Kit is a receptor tyrosine kinase, and it is encoded by the mouse W locus. Mutant W/Wv mice develop spontaneous gastric antral ulcers. The aim of the present study was to investigate the pathogenesis of these gastric ulcers and to examine the effects of two antiulcer drugs; a proton pump inhibitor (2{[4-(3-methoxypropoxy)-3-methylpyridine-2-yl]methyl-sulfinyl}-1H -benzimidazole sodium salt, rabeprazole) and a mucosal protective drug (geranylgeranylacetone, GGA), on the gastric ulcers. The inhibition of the gastric acid secretion by rabeprazole (30 mg/kg body weight, subcutaneous injection once a day for six weeks) significantly increased the gastric ulcer formation compared to the controls. In contrast, the GGA treatment (100 mg/kg body weight, oral administration for six weeks) significantly inhibited the ulcer formation. Bile reflux was seen in these mutant mice, and they showed no cyclic intense contractions in the gastric antrum. These results suggest that bile reflux due to the disturbance of gastric antral movement is a cause of the spontaneous gastric ulcers in W/Wv mice.

  2. Region 5: Ohio Parkersburg Adequate Letter (4/18/2007)

    EPA Pesticide Factsheets

    This letter from EPA to the Ohio Environmental Protection Agency determined the 2009 and 2018 motor vehicle emission budgets for (MVEBs) for volatile organic compounds (VOCs) and oxides of nitrogen (NOx) for Washington County 8-hour ozone nonattainment

  3. U.S. DOE Industrial Technologies Program – Technology Delivery Plant-Wide Assessment at PPG Industries, Natrium, WV

    SciTech Connect

    Lester, Stephen R.; Wiethe, Jeff; Green, Russell; Guice, Christina; Gopalakrishnan, Bhaskaran; Turton, Richard

    2007-09-28

    PPG and West Virginia University performed a plantwide energy assessment at the PPG’s Natrium, WV chemical plant, an energy-intensive manufacturing facility producing chlor-alkali and related products. Implementation of all the assessment recommendations contained in this report could reduce plant energy consumption by 8.7%, saving an estimated 10,023,192 kWh/yr in electricity, 6,113 MM Btu/yr in Natural Gas, 401,156 M lb/yr in steam and 23,494 tons/yr in coal and reduce carbon dioxide emissions by 241 mm lb/yr. The total cost savings would amount to approximately $2.9 mm/yr. Projects being actively implemented will save $1.7 mm/yr; the remainder are undergoing more detailed engineering study.

  4. Prospective evaluation of 2% (w/v) alcoholic chlorhexidine gluconate as an antiseptic agent for blood donor arm preparation

    PubMed Central

    Shah, Sweta; Mehta, Nidhi Ajay; Jadhav, Sweta Ganesh

    2014-01-01

    Aim: A prospective study was undertaken to evaluate the use of 2% (w/v) alcoholic chlorhexidine gluconate (2% AlcCHG) in donor arm preparation, to monitor the contamination rate of blood products after the collection and to find incidence of transfusion associated bacteremia. Settings and Design: Optimal skin antisepsis of the phlebotomy site is essential to minimize the risk of contamination. Food and Drug Administration (FDA) in India has recommended antisepsis with three-step regimen of spirit-10% povidone iodine-spirit for donor arm antisepsis, but not with chlorhexidine, which is recommended by many other authors. Material and Methods: A total of 795 donors were studied from July 2011 to January 2012. Spirit-10% povidone iodine-spirit was used for 398 donors and 2% AlcCHG was used for 397 donors with the two-step method for arm antisepsis. Swabs were collected before and after use of antiseptic agents for all the donors. All the blood products collected from donors with growth in post-antisepsis swabs were cultured. A total of 123 various blood products were cultured irrespective of the method and result of antisepsis was observed. A total of seven patients had mild transfusion reaction. The transfused blood products, blood and urine specimen of the patients who had transfusion reaction were also cultured. Results: Seven donors out of 398 donors had growth in post-antisepsis swab with spirit-10% povidone iodine-spirit protocol and three donors out of 397 donors had growth in post-antisepsis swab with 2% AlcCHG protocol. All blood products collected from donors who had growth in post-antisepsis swabs when cultured had no growth. There was no contamination of blood products. Conclusions: Two percent (w/v) alcoholic chlorhexidine gluconate with two-step protocol can be used as an antiseptic agent for donor arm preparation without considerable cost difference. It is at par with spirit 10% povidone iodine spirit protocol as suggested by FDA in India. There was no

  5. 6. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. STAGE, VOLCANO TOWN HALL. OLD GLORY, GETTING THE WORST OF IT. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  6. 10. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV. EPISCOPAL CHURCH AND GATES RESIDENCE AT LEFT (n.d.). - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  7. 8. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. INTERIOR VOLCANO TOWN HALL FROM STAGE SHOWING RAISED SEATS. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  8. 3. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV. LOOKING DOWN THE CREEK, WEST BACK OF THE STORES, BEFORE THE FIRE (n.d.). - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  9. 2. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1898. LARGE TANK, VOLOCANO STATION AND BAND HOUSE, AFTER THE RR WAS DISMANTLED. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  10. 23. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    23. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1897. TAKEN AT WATER TANKS NEAR THE HIGH TRESTLE. BOB FLEMING-ENGINEER, WILSH (?) ROLLINS-FIREMAN, OTH (?) COLLINS-PASSENGER (WITH CANE). - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  11. 11. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. JOHN SHAFFER'S STORE AND JOHN WILSON'S BOWLING ALLEY AND SALOON IN FOREGROUND. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  12. 21. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV. 'JOHN NOON L(*(. SAYS HE DROVE THE FIRST SPIKE AND I SAW HIM PULL THE LAST ONE AT VOLCANO JUNCTION' SBS. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  13. 18. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1998. THIS ENGINE HAD CAB KNOCKED OFF AND TIRES USED ON OTHER ENGINE, SO JOHN NOON AND PAT O'BRIEN WERE SCRAPING IT. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  14. 13. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. VOLCANO SCHOOL HOUSE, ME. CHURCH IN WOODS AT LEFT. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  15. 22. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1898. TANK, VOLCANO PUMPING STATION, AND BARNE HOUSE STILL STANDING AND IN USE. THIS SHOWS THE OLD RR LINE. (1934 CAPTION). - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  16. 15. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, UP THE HILL, SOUTH OF THE TOWN (n.d.). - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  17. 24. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    24. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. JIM RIDGE'S CARPENTER SHOP, LOOKING UP THE CREEK, EAST. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  18. 4. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. CORNER OF THORNHILL STORE AND TOWN HALL. MRS. GATES AND JOHN SCHAFFER. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  19. 20. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. RESIDENCE OF E.W. STAPLES AND DR. W.H. SHARP. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  20. Treatment of Neotrombicula species infestation in cats using a 10% (w/v) fipronil topical spot-on formulation: a pilot study.

    PubMed

    Cadiergues, Marie C; Navarro, Christelle; Castilla-Castaño, Eloy; Lecru, Line A; Pressanti, Charline

    2017-06-01

    Objectives Few data are available concerning therapeutic aspects of feline trombiculiasis. This study evaluated the efficacy of a 10% w/v fipronil-based spot-on solution in 15 cats with natural Neotrombicula species infestation. Methods Ten cats received 1 drop per affected site on day (D)0 and D14, with the rest of the 0.5 ml pipette applied on the skin between the shoulders. Five cats served as non-treated controls. Parasite score (0 = absent; 3 = severe, >10 parasites/zone) was assessed on D0, D14 and D28 on all animals. Skin lesions (SCORing Feline Allergic Dermatitis lesion severity scale [SCORFAD]) and investigator pruritus scale (IPS; 0 = cat comfortable, grooming like any normal cat; 4 = cat uncomfortable, pruritic all the time) were assessed on treated cats on the same days. Global assessment of efficacy, tolerance and ease of use (GAS; 1 = very poor; 5 = excellent) was assessed on D28. Results All the cats completed the study. Parasite scores of the control cats were maintained throughout the trial (mean ± SD: D0 4 ± 0.7, D14 3.2 ± 1.1 and D28 3.2 ± 0.4). In treated cats, SCORFAD (D0 3.2 ± 5.4, D14 1.1 ± 2.1 [ P <0.002] and D28 0.5 ± 1.3 [ P <0.002]), parasite (D0 3.9 ± 1.3, D14 1.2 ± 0.8 [ P <0.005] and D28 0.4 ± 0.5 [ P <0.005]) and IPS (D0 1 ± 1.2, D14 0.5 ± 1.1 [ P <0.05] and D28 0.3 ± 0.7 [ P <0.05]) scores significantly decreased throughout the trial. On D28, the GAS was 4.2 ± 0.9. There were no adverse effects from treatment. Conclusions and relevance The 10% w/v fipronil preparation appeared to be effective, safe and practical in the treatment of localised Neotrombicula species infestation in these cats.

  1. Category and perceptual interference in second-language phoneme learning: an examination of English /w/-/v/ learning by Sinhala, German, and Dutch speakers.

    PubMed

    Iverson, Paul; Ekanayake, Dulika; Hamann, Silke; Sennema, Anke; Evans, Bronwen G

    2008-10-01

    The present study investigated the perception and production of English /w/ and /v/ by native speakers of Sinhala, German, and Dutch, with the aim of examining how their native language phonetic processing affected the acquisition of these phonemes. Subjects performed a battery of tests that assessed their identification accuracy for natural recordings, their degree of spoken accent, their relative use of place and manner cues, the assimilation of these phonemes into native-language categories, and their perceptual maps (i.e., multidimensional scaling solutions) for these phonemes. Most Sinhala speakers had near-chance identification accuracy, Germans ranged from chance to 100% correct, and Dutch speakers had uniformly high accuracy. The results suggest that these learning differences were caused more by perceptual interference than by category assimilation; Sinhala and German speakers both have a single native-language phoneme that is similar to English /w/ and /v/, but the auditory sensitivities of Sinhala speakers make it harder for them to discern the acoustic cues that are critical to /w/-/v/ categorization.

  2. Diluting ferric carboxymaltose in sodium chloride infusion solution (0.9% w/v) in polypropylene bottles and bags: effects on chemical stability

    PubMed Central

    Philipp, Erik; Braitsch, Michaela; Bichsel, Tobias; Mühlebach, Stefan

    2016-01-01

    Objectives This study was designed to assess the physicochemical stability of colloidal ferric carboxymaltose solution (Ferinject) when diluted and stored in polypropylene (PP) bottles and bags for infusion. Methods Two batches of ferric carboxymaltose solution (Ferinject) were diluted (500 mg, 200 mg and 100 mg iron in 100 mL saline) in PP bottles or bags under aseptic conditions. The diluted solutions were stored at 30°C and 75%±5% relative humidity (rH) for 72 h, and samples were withdrawn aseptically at preparation and after 24 h, 48 h and 72 h. Multiple parameters were used to test stability-related measures (pH, total iron and iron (II) content, molecular weight range determination, microbial contamination and particles count ≥10 μm). Results Overall, Ferinject diluted in 0.9% (w/v) NaCl solution and stored in PP bottles and bags was stable within the specifications for the complex and the acceptability limits set for all assays. In both containers, total iron content remained stable, within 10% of the theoretical iron content, and levels of iron (II) remained far below the threshold of acceptability. All preparations were free from sediments, particle numbers were acceptable and there was no microbial contamination. The molecular weight distribution and polydispersity index were also acceptable. Conclusions Under the tested experimental conditions, colloidal ferric carboxymaltose solution (Ferinject) diluted in saline in PP infusion bottles or bags demonstrated physical and chemical stability for up to 72 h at 30°C and 75% rH. Because of the lack of additional clinical data, when using ferric carboxymaltose, physicians/pharmacists should refer to the dilution and storing recommendations given in the product's summary of product characteristics. PMID:26835007

  3. Two WV-MnIII bimetallic assemblies built by octacyanotungstate(v) and MnIII Schiff bases: molecular structures and a spin-flop transition.

    PubMed

    Ko, Hyun Hee; Lim, Jeong Hak; Yoo, Houng Sik; Kang, Jun Sung; Kim, Hyoung Chan; Koh, Eui Kwan; Hong, Chang Seop

    2007-05-28

    Two W(V)-Mn(III) bimetallic compounds, [Mn(Cl-salmen)(H(2)O)2]{[Mn(5-Clsalmen)(H(2)O)]2[W(CN)8].2H(2)O (1.2H(2)O) [5-Clsalmen = N,N'-(1-methylethylene)bis(5-chlorosalicylideneiminato) dianion], which contains trinuclear Mn(2)W and isolated Mn(III) moieties, and [Mn(3-MeOsalcy)(H(2)O)2]3[W(CN)(8)].2H(2)O (2.2H(2)O) [3-MeOsalcy = N,N'-(trans-1,2-cyclohexanediylethylene)bis(3-methoxysalicylideneiminato) dianion] molecules were prepared in redox processes and characterized using X-ray analysis and magnetic measurements. Compound 1 is composed of the {[Mn(5-Clsalmen)(H(2)O)]2[W(CN)8]}- trimer, in which two CN groups among eight in [W(CN)8](3-) bridge W(5+) and two Mn(3+) ions and the remaining CN ligands are hydrogen-bonded to water molecules or unbound, and the [Mn(Cl-salmen)(H(2)O)2]+ cation. Subsequently, two water molecules of the isolated cation are subject to hydrogen bonds. For 2, there are no covalent bonds among the subunits and six serial stacks of [Mn(3-MeOsalcy)(H(2)O)2]+ units are all hydrogen-bonded. The many hydrogen bonds found in both complexes eventually lead to three-dimensional networks. The magnetic studies for 1 reveal that antiferromagnetic interactions (J = -5.4 cm(-1)) between W(V) and Mn(III) centers within the trimer are transmitted via the bridging CN groups. Intermolecular antiferromagnetic couplings (zJ' = -0.2 cm(-1)) are also observed. The static and dynamic magnetic data of 1 demonstrate the existence of a field-induced spin-flop transition occurring among the clusters and monomeric molecules.

  4. Upscaling the impact of convective overshooting (COV) through BRAMS: a continental and wet-season scale study of the water vapour (WV) budget in the tropical tropopause layer (TTL).

    NASA Astrophysics Data System (ADS)

    Behera, Abhinna; Rivière, Emmanuel; Marécal, Virginie; Rysman, Jean-François; Claud, Chantal; Burgalat, Jérémie

    2017-04-01

    The stratospheric water vapour (WV) has a conceding impact on the radiative and chemical budget of Earth's atmosphere. The convective overshooting (COV) at the tropics is well admitted for playing a role in transporting directly WV to the stratosphere. Nonetheless, its impact on the lower stratosphere is yet to be determined at global scale, as the satellite and other air-borne measurements are not of having fine enough resolution to quantify this impact at large scale. Therefore, efforts have been made to quantify the influence of COV over the WV budget in the tropical tropopause layer (TTL) through modelling. Our approach is to build two synthetic tropical wet-seasons; where one would be having only deep convection (DC) but no COV at all, and the second one would be having the COV, and in both cases the WV budget in the TTL would be estimated. Before that, a French-Brazilian TRO-pico campaign was carried out at Bauru, Brazil in order to understand the influence of COV on the WV budget in the TTL. The radio-sounding, and the small balloon-borne WV measurements from the campaign are being utilized to validate the model simulation. Brazilian version of Regional Atmospheric Modeling System (BRAMS) is used with a single grid system to simulate a WV variability in a wet-season. Grell's convective parameterization with ensemble closure, microphysics with double moment scheme and 7 types of hydrometeors are incorporated to simulate the WV variability for a wet-season at the tropics. The grid size of simulation is chosen to be 20 km x 20 km horizontally and from surface to 30 km altitude, so that there cannot be COV at all, only DC due to such a relatively coarse resolution. The European Centre for Medium-range Weather Forecasts (ECMWF) operational analyses data are used every 6 hours for grid initialization and boundary conditions, and grid center nudging. The simulation is carried out for a full wet-season (Nov 2012 - Mar 2013) at Brazilian scale, so that it would

  5. Phenotypic changes of bone marrow-derived mast cells after intraperitoneal transfer into W/Wv mice that are genetically deficient in mast cells

    PubMed Central

    1987-01-01

    The ability of mouse IL-3-dependent, bone marrow culture-derived mast cells (BMMC) to generate serosal mast cells (SMC) in vivo after adoptive transfer to mast cell-deficient mice has been defined by chemical and immunochemical criteria. BMMC differentiated and grown from WBB6F1-+/+ mouse progenitor cells in medium containing PWM/splenocyte-conditioned medium synthesized a approximately 350,000 Mr protease-resistant proteoglycan bearing approximately 55,000 Mr glycosaminoglycans, as defined by gel filtration of each. Approximately 85% of the glycosaminoglycans bound to the cell-associated BMMC proteoglycans were chondroitin sulfates based upon their susceptibility to chondroitinase ABC digestion; HPLC of the chondroitinase ABC- generated unsaturated disaccharides revealed these glycosaminoglycans to be chondroitin sulfate E. As determined by heparinase and nitrous acid degradations, approximately 10% of the glycosaminoglycans bound to BMMC proteoglycans were heparin. In contrast, mast cells recovered from the peritoneal cavity of congenitally mast cell-deficient WBB6F1-W/Wv mice 15 wk after intraperitoneal injection of BMMC synthesized approximately 650,000 Mr protease-resistant proteoglycans that contained approximately 80% heparin glycosaminoglycans of approximately 105,000 Mr. Thus, after adoptive transfer, the SMC of the previously mast cell-deficient mice were like those recovered from the normal WBB6F1-+/+ mice that were shown to synthesize approximately 600,000 Mr proteoglycans that contained approximately 80% heparin glycosaminoglycans of approximately 115,000 Mr. As assessed by indirect immunofluorescence staining and flow cytometry using the B1.1 rat mAb (an antibody that recognizes an epitope located on the neutral glycosphingolipid globopentaosylceramide), approximately 5% of BMMC bound the antibody detectably, whereas approximately 72% of the SMC that were harvested from mast cell-deficient mice 15 wk after adoptive transfer of BMMC were B1.1-positive

  6. ADAPTING EDUCATIONAL CHANGE TO MANPOWER NEEDS IN QUINCY, MASSACHUSETTS, AND WOOD COUNTY (PARKERSBURG), WEST VIRGINIA.

    ERIC Educational Resources Information Center

    ROGERS, VIRGIL M.

    PRESENT PROCEDURES AND INNOVATIONS RESULTING FROM TECHNOLOGICAL CHANGES WERE EXAMINED IN TWO REPRESENTATIVE SCHOOL SYSTEMS TO HELP OTHER SCHOOLS, BOARDS, AND FACULTIES FACING COMPARABLE PROBLEMS. THE STUDY FOCUSED ON MANPOWER TRAINING AND DEVELOPMENT, THE RESOURCES AVAILABLE IN THE COMMUNITY, THE PROFESSIONAL STAFF OF THE SCHOOLS, THE RECEPTIVITY…

  7. 12 CFR 615.5461 - Lost, stolen, destroyed, mutilated or defaced Farm Credit securities, including coupons.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ADMINISTRATION FARM CREDIT SYSTEM FUNDING AND FISCAL AFFAIRS, LOAN POLICIES AND OPERATIONS, AND FUNDING OPERATIONS Book-Entry Procedures for Farm Credit Securities § 615.5461 Lost, stolen, destroyed, mutilated or... Public Debt, P.O. Box 396, Parkersburg, WV 26102-0396, in the case of consolidated or...

  8. 77 FR 32179 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-31

    ... Department of the Treasury is soliciting comments concerning the Certificate of Identity. DATES: Written..., Parkersburg, WV 26106-1328, (304) 480-8150. SUPPLEMENTARY INFORMATION: Title: Certificate of Identity. OMB... identity of the owner of the United States Savings Securities. Current Actions: None. Type of...

  9. 49 CFR 372.207 - Charleston, WV.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... foreign commerce, not under common control, management, or arrangement for a continuous carriage or... this section, and (e) All of any municipality wholly surrounded, or so surrounded except for a...

  10. 49 CFR 372.215 - Ravenswood, WV.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... foreign commerce, not under common control, management, or arrangement for a continuous carriage or... the limits of the combined areas defined in paragraphs (b) and (c) of this section, and (e) All of...

  11. Studies on localization and function of annexin A4a within urinary bladder epithelium using a mouse knockout model.

    PubMed

    Hill, Warren G; Meyers, Susan; von Bodungen, Maximilian; Apodaca, Gerard; Dedman, John R; Kaetzel, Marcia A; Zeidel, Mark L

    2008-04-01

    Annexin A4 (anxA4) is a member of the Ca(2+)-dependent membrane-binding family of proteins implicated in the regulation of ion conductances, Ca(2+) homeostasis, and membrane trafficking. We demonstrate, in mice, that annexins 1-6 are present in whole bladder and exhibit differential expression in the urothelium. An anxA4a-knockout (anxA4a(-/-)) mouse model shows no protein in the urothelium by immunofluorescence and immunoblotting. In wild-type bladders, anxA4a in umbrella cells showed uniform cytoplasmic staining and some association with the nuclear membrane. Application of a hydrostatic pressure to bladders mounted in Ussing chambers resulted in redistribution of anxA4a from cytoplasm to cellular boundaries in the basal and intermediate cells but not in superficial umbrella cells. We hypothesized that anxA4a might be important for barrier function or for stretch-activated membrane trafficking. To test these hypotheses, we conducted a series of functional and morphological analyses on bladders from control and anxA4a(-/-) animals. The transepithelial resistances, water permeabilities, and urea permeabilities of anxA4a(-/-) bladders were not different from controls, indicating that barrier function was intact. Membrane trafficking in response to hydrostatic pressure as measured by capacitance increases was also normal for anxA4a(-/-) bladders. Cystometrograms performed on live animals showed that voiding frequency and intrabladder pressures were also not different. There were no differences in bladder surface morphology or cellular architecture examined by scanning and transmission electron microscopy, respectively. We conclude that loss of anxA4 from the urothelium does not affect barrier function, membrane trafficking, or normal bladder-voiding behavior.

  12. Evaluation of the Adulticidal Efficacy of Imidacloprid 10 %/Moxidectin 2.5 % (w/v) Spot-on (Advocate®, Advantage® Multi) against Dirofilaria repens in Experimentally Infected Dogs.

    PubMed

    Petry, Gabriele; Genchi, Marco; Schmidt, Holger; Schaper, Roland; Lawrenz, Bettina; Genchi, Claudio

    2015-08-01

    This study aimed to evaluate the efficacy of imidacloprid 10 %/moxidectin 2.5 % (w/v) spot-on (Advocate®/Advantage® Multi, Bayer) against adult Dirofilaria repens in a blinded, placebo-controlled randomised laboratory study. Twenty-four Beagle dogs were experimentally infected with approximately 75 infective D. repens larvae each on study day (SD) 0. Treatment was initiated on SD 228 after patency had been confirmed in 21 dogs, using a modified Knott Test. Eleven dogs received monthly treatments with imidacloprid/moxidectin at the minimum therapeutic dose (10 mg/kg imidacloprid and 2.5 mg/kg moxidectin) for six consecutive months and 12 control dogs were treated with a placebo formulation. Approximately one month after the last treatment, all dogs were euthanised and necropsied for the detection of D. repens worms. Eleven control dogs harboured live adult D. repens (range 2-11, geometric mean 5.44). Eight of 11 imidacloprid/moxidectin-treated dogs were free of live worms. The live worm count was reduced by 96.2 % (range 0-1, geometric mean 0.21). The majority of dead worms were encapsulated and degenerated. After the first treatment, Knott Tests were negative in all imidacloprid/moxidectin-treated dogs and this status was maintained in 10 dogs until study end. One dog showed a low microfilariae count (1 and 4/mL) on four occasions but was also negative before necropsy. The treatment was well tolerated by all study animals. It is concluded that six consecutive monthly treatments with imidacloprid/moxidectin spot-on are effective and safe against adult D. repens and provide an option for preventing the further spread of this zoonotic parasite.

  13. Inhibition of cytochrome P450 enzymes by saturated and unsaturated fatty acids in human liver microsomes, characterization of enzyme kinetics in the presence of bovine serum albumin (0.1 and 1.0% w/v) and in vitro - in vivo extrapolation of hepatic clearance.

    PubMed

    Palacharla, Raghava Choudary; Uthukam, Venkatesham; Manoharan, Arunkumar; Ponnamaneni, Ranjith Kumar; Padala, Nagasurya Prakash; Boggavarapu, Rajesh Kumar; Bhyrapuneni, Gopinadh; Ajjala, Devender Reddy; Nirogi, Ramakrishna

    2017-04-01

    The objective of the study was to determine the effect of fatty acids on CYP enzymes and the effect of BSA on intrinsic clearance of probe substrates. The inhibitory effect of thirteen fatty acids including saturated, mono-unsaturated and polyunsaturated fatty acids on CYP enzymes, kinetic parameters and intrinsic clearance values of nine CYP marker probe substrate reactions in the absence and presence of BSA (0.1 and 1.0% w/v) were characterized in human liver microsomes. The results demonstrate that most of the unsaturated fatty acids showed marked inhibition towards CYP2C8 mediated amodiaquine N-deethylation followed by inhibition of CYP2C9 and CYP2B6 mediated activities. The addition of 0.1% BSA in the incubation markedly improved the unbound intrinsic clearance values of probe substrates by reducing the Km values with little or no effect on maximal velocity. The addition of BSA (0.1 and 1.0% w/v) did not influence the unbound intrinsic clearance of marker reactions for CYP2A6, and CYP3A4 enzymes. The addition of 0.1% w/v BSA is sufficient to determine the intrinsic clearance of marker probe reactions by metabolite formation approach. The predicted hepatic clearance values for the substrates using the well-stirred model, in the presence of BSA (0.1% BSA), are comparable to the in vivo hepatic clearance values.

  14. Linkage and association of haplotypes at the APOA1/C3/A4/A5 genecluster to familial combined hyperlipidemia

    SciTech Connect

    Eichenbaum-Voline, Sophie; Olivier, Michael; Jones, Emma L.; Naoumova, Rossitza P.; Jones, Bethan; Gau, Brian; Seed, Mary; Betteridge,D. John; Galton, David J.; Rubin, Edward M.; Scott, James; Shoulders,Carol C.; Pennacchio, Len A.

    2002-09-15

    Combined hyperlipidemia (CHL) is a common disorder of lipidmetabolism that leads to an increased risk of cardiovascular disease. Thelipid profile of CHL is characterised by high levels of atherogeniclipoproteins and low levels of high-density-lipoprotein-cholesterol.Apolipoprotein (APO) A5 is a newly discovered gene involved in lipidmetabolism located within 30kbp of the APOA1/C3/A4 gene cluster. Previousstudies have indicated that sequence variants in this cluster areassociated with increased plasma lipid levels. To establish whethervariation at the APOA5 gene contributes to the transmission of CHL, weperformed linkage and linkage disequilibrium (LD) tests on a large cohortof families (n=128) with familial CHL (FCHL). The linkage data producedevidence for linkage of the APOA1/C3/A4/A5 genomic interval to FCHL (NPL= 1.7, P = 0.042). The LD studies substantiated these data. Twoindependent rare alleles, APOA5c.56G and APOC3c.386G of this gene clusterwere over-transmitted in FCHL (P = 0.004 and 0.007, respectively), andthis was associated with a reduced transmission of the most commonAPOA1/C3/A4/A5 haplotype (frequency 0.4425) to affected subjects (P =0.013). The APOA5c.56G allele was associated with increased plasmatriglyceride levels in FCHL probands, whereas the second, andindependent, APOC3c.386G allele was associated with increased plasmatriglyceride levels in FCHL pedigree founders. Thus, this allele (or anallele in LD) may mark a quantitative trait associated with FCHL, as wellas representing a disease susceptibility locus for the condition. Thisstudy establishes that sequence variation in the APOA1/C3/A4/A5 genecluster contributes to the transmission of FCHL in a substantialproportion of affected families, and that these sequence variants mayalso contribute to the lipid abnormalities of the metabolic syndrome,which is present in up to 40 percent of persons with cardiovasculardisease.

  15. Orthologs of the class A4 heat shock transcription factor HsfA4a confer cadmium tolerance in wheat and rice.

    PubMed

    Shim, Donghwan; Hwang, Jae-Ung; Lee, Joohyun; Lee, Sichul; Choi, Yunjung; An, Gynheung; Martinoia, Enrico; Lee, Youngsook

    2009-12-01

    Cadmium (Cd) is a widespread soil pollutant; thus, the underlying molecular controls of plant Cd tolerance are of substantial interest. A screen for wheat (Triticum aestivum) genes that confer Cd tolerance to a Cd hypersensitive yeast strain identified Heat shock transcription factor A4a (HsfA4a). Ta HsfA4a is most similar to the class A4 Hsfs from monocots. The most closely related rice (Oryza sativa) homolog, Os HsfA4a, conferred Cd tolerance in yeast, as did Ta HsfA4a, but the second most closely related rice homolog, Os HsfA4d, did not. Cd tolerance was enhanced in rice plants expressing Ta HsfA4a and decreased in rice plants with knocked-down expression of Os HsfA4a. An analysis of the functional domain using chimeric proteins constructed from Ta HsfA4a and Os HsfA4d revealed that the DNA binding domain (DBD) of HsfA4a is critical for Cd tolerance, and within the DBD, Ala-31 and Leu-42 are important for Cd tolerance. Moreover, Ta HsfA4a-mediated Cd resistance in yeast requires metallothionein (MT). In the roots of wheat and rice, Cd stress caused increases in HsfA4a expression, together the MT genes. Our findings thus suggest that HsfA4a of wheat and rice confers Cd tolerance by upregulating MT gene expression in planta.

  16. Effects of variations in the APOA1/C3/A4/A5 gene cluster on different parameters of postprandial lipid metabolism in healthy young men

    USDA-ARS?s Scientific Manuscript database

    Background: The APOA1/C3/A4/A5 gene cluster encodes important regulators of fasting lipids, but the majority of lipid metabolism takes place in the postprandial state, and knowledge about gene regulation in this state is scarce. With the aim of characterizing possible regulators of lipid metabolism...

  17. The APOA1/C3/A4/A5 cluster and markers of allostatic load in the Boston Puerto Rican Health Study

    USDA-ARS?s Scientific Manuscript database

    The APOA1/C3/A4/A5 cluster encodes key regulators of plasma lipids. Interactions between dietary factors and single nucleotide polymorphisms (SNPs) in the cluster have been reported. Allostatic load, or physiological dysregulation in response to stress, has been implicated in shaping health disparit...

  18. Nobody Asked Us: The WV Welfare Reform Listening Project.

    ERIC Educational Resources Information Center

    Wilson, Rick

    West Virginia's state welfare reform plan was in effect by the end of 1997. In 1999, over 175 interviews were conducted with past and present welfare recipients to bring their experiences and concerns to the attention of the public and policymakers. Nearly all interviewees were women and were taking part in work activities. In general, welfare…

  19. 76 FR 80230 - Amendment of Class E Airspace; Huntington, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-23

    .../Milton J. Ferguson Field Airport. This action enhances the safety and management of Instrument Flight... developed for Tri-State/Milton J. Ferguson Field Airport. The Huntt NDB has been decommissioned, and the NDB... scope of that authority as it amends controlled airspace at Tri-State/Milton J. Ferguson Field...

  20. Argus Energy WV, LLC wins 2007 Wetlands West Virginia Award

    SciTech Connect

    2007-07-15

    Argus Energy's Kiah Creek Operation has received the 2007 Wetlands West Virginia Award presented by the West Virginian Coal Association. The operation was originally a 1267 acre underground mine in the Coalburg seam. Underground mining commenced in 2000 until the end of 2003 with more than two million tons of coal being produced. The creation of the wetlands was achieved during the operations. 8 photos.

  1. Skidders, Trucking, and Fellers limiting Factors in WV Logging Industry

    Treesearch

    William G. Luppold; Curt C. Hassler; Shawn Grushecky; Shawn Grushecky

    1998-01-01

    Like many states in the Central Appalachian region West Virginia has experienced a continual expansion in primary hardwood processing capacity during the 1990s. In the early part of the decade, hardwood sawmill capacity increased by nearly 40 percent to more than 700 million board feet per year. In the mid and late 1990s, several other primary processing facilities...

  2. 77 FR 3836 - Supplemental Environmental Impact Statement, Mingo County, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-25

    ... portion of the King Coal Highway 2000 FEIS and the Buffalo Mountain Surface Mine Clean Water Act Section... USACE is evaluating a Clean Water Act (CWA) Section 404 Individual Permit (IP) application submitted by....S.) in conjunction with the construction and operation of the Buffalo Mountain Surface Mine....

  3. 75 FR 22871 - West Virginia Disaster # WV-00018

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-30

    ... snowstorms. Incident Period: 02/05/2010 through 02/11/2010. Effective Date: 04/23/2010. Physical Loan Application Deadline Date: 06/22/2010. Economic Injury (EIDL) Loan Application Deadline Date: 01/24/2011... P. Loddo, Acting Associate Administrator for Disaster Assistance. BILLING CODE 8025-01-P...

  4. 76 FR 34606 - Special Local Regulation; Monongahela River, Morgantown, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-14

    ... safeguard participants during the Mountaineer Triathlon marine event from the hazards imposed by marine... regulation is being established to safeguard participants of the Mountaineer Triathlon from the hazards of marine traffic. Entry into, movement within, and departure from this Coast Guard regulated area...

  5. 77 FR 17561 - West Virginia Disaster #WV-00023

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-26

    ...This is a Notice of the Presidential declaration of a major disaster for the State of West Virginia (FEMA-4059-DR), dated 03/16/ 2012. Incident: Severe Storms, Tornadoes, Flooding, Mudslides, and Landslides. Incident Period: 02/29/2012 through 03/05/2012.

  6. Effects of variations in the APOA1/C3/A4/A5 gene cluster on different parameters of postprandial lipid metabolism in healthy young men.

    PubMed

    Delgado-Lista, Javier; Perez-Jimenez, Francisco; Ruano, Juan; Perez-Martinez, Pablo; Fuentes, Francisco; Criado-Garcia, Juan; Parnell, Laurence D; Garcia-Rios, Antonio; Ordovas, Jose M; Lopez-Miranda, Jose

    2010-01-01

    The APOA1/C3/A4/A5 gene cluster encodes important regulators of fasting lipids, but the majority of lipid metabolism takes place in the postprandial state and knowledge about gene regulation in this state is scarce. With the aim of characterizing possible regulators of lipid metabolism, we studied the effects of nine single nucleotide polymorphisms (SNPs) during postprandial lipid metabolism. Eighty-eight healthy young men were genotyped for APOA1 -2630 (rs613808), APOA1 -2803 (rs2727784), APOA1 -3012 (rs11216158), APOC3 -640 (rs2542052), APOC3 -2886 (rs2542051), APOC3 G34G (rs4520), APOA4 N147S (rs5104), APOA4 T29T (rs5092), and A4A5_inter (rs1263177) and were fed a saturated fatty acid-rich meal (1g fat/kg of weight with 60% fat, 15% protein and 25% carbohydrate). Serial blood samples were extracted for 11 h after the meal. Total cholesterol and fractions [HDL-cholesterol, LDL-cholesterol, trifacylglycerols (TGs) in plasma, TG-rich lipoproteins (TRLs) (large TRLs and small TRLs), apolipoprotein A-I and apolipoprotein B] were determined. APOA1 -2803 homozygotes for the minor allele and A4A5_inter carriers showed a limited degree of postprandial lipemia. Carriers of the rare alleles of APOA4 N147S and APOA4 T29T had lower APOA1 plasma concentration during this state. APOC3 -640 was associated with altered TG kinetics but not its magnitude. We have identified new associations between SNPs in the APOA1/C3/A4/A5 gene cluster and altered postprandial lipid metabolism.

  7. Nigellamines A3, A4, A5, and C, new dolabellane-type diterpene alkaloids, with lipid metabolism-promoting activities from the Egyptian medicinal food black cumin.

    PubMed

    Morikawa, Toshio; Xu, Fengming; Ninomiya, Kiyofumi; Matsuda, Hisashi; Yoshikawa, Masayuki

    2004-04-01

    New dolabellane-type diterpene alkaloids, nigellamines A(3), A(4), A(5), and C, were isolated from the methanolic extract of an Egyptian medicinal food, black cumin (the seeds of Nigella sativa). Their absolute configurations were determined on the basis of chemical and physicochemical evidence. Nigellamines were found to lower triglyceride levels in primary cultured mouse hepatocytes, and in particular, the activity of nigellamine A(5) was equivalent to that of the hypolipidemic agent, clofibrate.

  8. Sputtering Deposition of Sandwich-Structured V2O5/Metal (V, W)/V2O5 Multilayers for the Preparation of High-Performance Thermally Sensitive VO2 Thin Films with Selectivity of VO2 (B) and VO2 (M) Polymorph.

    PubMed

    Liu, Hengwu; Wan, Dongyun; Ishaq, Ahmad; Chen, Lanli; Guo, Beibei; Shi, Siqi; Luo, Hongjie; Gao, Yanfeng

    2016-03-01

    For specific application to an uncooled infrared detector, VO2 thin films should have a series of characteristics including purposefully chosen polymorphs, accurate stoichiometry, phase stabilization, a high temperature-coefficient of resistance (TCR), and suitable square-resistance. This work reports controllable preparation of high-performance VO2 films via post annealing of a sandwich-structured V2O5/metal (V, W)/V2O5 multilayer precursor, which was deposited by RF magnetron sputtering. This sandwich structure can dynamically regulate oxygen contents and doping element levels in the films, enabling us to achieve accurate regulation of stoichiometry and polymorphs. The precursor films undergo a B to M phase transition depending on the quantity of the metal layers. At the thickness of the metal layer below a limitation, the resulting film after heat treatment was VO2 (B), and above the limitation, the product was VO2 (M). The optical modulation of the VO2 (M) in the near-infrared region can be tuned from 1.2 to 39.8% (ΔT2000 nm). TCR values can range from -1.89 to -4.29%/K and the square-resistances at room temperature (R0) from 69.68 to 12.63 kΩ. The simplicity in phase regulation of the present method and the superior optical and electrical properties of the films may allow its wide applications in thermo-opto-electro sensing devices.

  9. Molecules based on M(v) (M=Mo, W) and Ni(II) ions: a new class of trigonal bipyramidal cluster and confirmation of SMM behavior for the pentadecanuclear molecule {NiII[NiII(tmphen)(MeOH)]6[Ni(H2O)3]2[micro-CN]30[WV(CN)3]6}.

    PubMed

    Hilfiger, Matthew G; Zhao, Hanhua; Prosvirin, Andrey; Wernsdorfer, Wolfgang; Dunbar, Kim R

    2009-07-14

    The preparation, single crystal X-ray crystallography, and magnetic properties are reported for four new clusters based on [M'V(CN)8]3- octacyanometallates (M'=Mo, W). Reactions of [M'V(CN)8]3- with mononuclear NiII ions in the presence of the tmphen blocking ligand (tmphen=3,4,7,8-tetramethyl-1,10-phenanthroline) in a 2:3:6 ratio, respectively, lead to the formation of the trigonal bipyramidal clusters [NiII(tmphen)2]3[M'V(CN)8]2. Analogous reactions with the same starting materials performed in a 2:3:2 ratio, respectively, produce pentadecanuclear clusters of the type {NiII[NiII(tmphen)(MeOH)]6[Ni(H2O)3]2[micro-CN]30[WV(CN)3]6}. The W2Ni3 (1) and Mo2Ni3(2) pentanuclear clusters and the W6Ni9 (3) and Mo6Ni9 (4) pentadecanuclear molecules are isostructural to each other and crystallize in the space groups P2(1)/c and R3 respectively. Magnetic measurements indicate that the ground states for the trigonal bipyamidal clusters are S=4 as a consequence of ferromagnetic coupling with JW-Ni=9.5 cm(-1), JMo-Ni=10 cm(-1). The pentadecanuclear clusters exhibit ferromagnetic coupling as well, which leads to S=12 ground states (JW-Ni=12 cm(-1), JMo-Ni=12.2 cm(-1)). Reduced magnetization studies on the W-Ni analogues support the conclusion that they exhibit a negative axial anisotropy term; the fits give D values of -0.24 cm(-1) for the W2Ni3 cluster and D=-0.04 cm(-1)for the W6Ni9 cluster. AC susceptibility measurements indicate the beginning of an out-of-phase signal for the W2Ni3 and the W6Ni9 compounds, but detailed low temperature studies on small crystals by the microSQUID technique indicate that only the pentadecanuclear cluster exhibits hysteresis in accord with SMM behavior. Neither Mo cluster reveals any evidence for slow paramagnetic relaxation at low temperatures.

  10. High-spin molecules: synthesis, X-ray characterization, and magnetic behavior of two new cyano-bridged Ni(II)(9)Mo(V)(6) and Ni(II)(9)W(V)(6) clusters with a S = 12 ground state.

    PubMed

    Bonadio, Federica; Gross, Mathias; Stoeckli-Evans, Helen; Decurtins, Silvio

    2002-11-04

    The preparations, X-ray structures, and magnetic characterizations are presented for two new pentadecanuclear cluster compounds: [Ni(II)(Ni(II)(MeOH)(3))(8)(mu-CN)(30)(M(V)(CN)(3))(6)].xMeOH.yH(2)O (M(V) = Mo(V) (1) with x = 17, y = 1; M(V) = W(V) (2) with x = 15, y = 0). Both compounds crystallize in the monoclinic space group C2/c, with cell dimensions of a = 28.4957(18) A, b = 19.2583(10) A, c = 32.4279(17) A, beta = 113.155(6) degrees, and Z = 4 for 1 and a = 28.5278(16) A, b = 19.2008(18) A, c = 32.4072(17) A, beta = 113.727(6) degrees, and Z = 4 for 2. The structures of 1 and 2 consist of neutral cluster complexes comprising 15 metal ions, 9 Ni(II) and 6 M(V), all linked by mu-cyano ligands. Magnetic susceptibilities and magnetization measurements of compounds 1 and 2 in the crystalline and dissolved state indicate that these clusters have a S = 12 ground state, originating from intracluster ferromagnetic exchange interactions between the mu-cyano-bridged metal ions of the type Ni(II)-NC-M(V). Indeed, these data show clearly that the cluster molecules stay intact in solution. Ac magnetic susceptibility measurements reveal that the cluster compounds exhibit magnetic susceptibility relaxation phenomena at low temperatures since, with nonzero dc fields, chi"(M) has a nonzero value that is frequency dependent. However, there appears no out-of-phase (chi"(M)) signal in zero dc field down to 1.8 K, which excludes the expected signature for a single molecule magnet. This finding is confirmed with the small uniaxial magnetic anisotropy value for D of 0.015 cm(-1), deduced from the high-field, high-frequency EPR measurement, which distinctly reveals a positive sign in D. Obviously, the overall magnetic anisotropy of the compounds is too low, and this may be a consequence of a small single ion magnetic anisotropy combined with the highly symmetric arrangement of the metal ions in the cluster molecule.

  11. Haplotypes in the APOA1-C3-A4-A5 gene cluster affect plasma lipids in both humans and baboons

    SciTech Connect

    Wang, Qian-fei; Liu, Xin; O'Connell, Jeff; Peng, Ze; Krauss, Ronald M.; Rainwater, David L.; VandeBerg, John L.; Rubin, Edward M.; Cheng, Jan-Fang; Pennacchio, Len A.

    2003-09-15

    Genetic studies in non-human primates serve as a potential strategy for identifying genomic intervals where polymorphisms impact upon human disease-related phenotypes. It remains unclear, however, whether independently arising polymorphisms in orthologous regions of non-human primates leads to similar variation in a quantitative trait found in both species. To explore this paradigm, we studied a baboon apolipoprotein gene cluster (APOA1/C3/A4/A5) for which the human gene orthologs have well established roles in influencing plasma HDL-cholesterol and triglyceride concentrations. Our extensive polymorphism analysis of this 68 kb gene cluster in 96 pedigreed baboons identified several haplotype blocks each with limited diversity, consistent with haplotype findings in humans. To determine whether baboons, like humans, also have particular haplotypes associated with lipid phenotypes, we genotyped 634 well characterized baboons using 16 haplotype tagging SNPs. Genetic analysis of single SNPs, as well as haplotypes, revealed an association of APOA5 and APOC3 variants with HDL cholesterol and triglyceride concentrations, respectively. Thus, independent variation in orthologous genomic intervals does associate with similar quantitative lipid traits in both species, supporting the possibility of uncovering human QTL genes in a highly controlled non-human primate model.

  12. Synthesis and Spectroscopic and Cellular Properties of Near-IR [a]Phenanthrene-Fused 4,4-Difluoro-4-bora-3a,4a-diaza-s-indacenes.

    PubMed

    Zhao, Ning; Xuan, Sunting; Zhou, Zehua; Fronczek, Frank R; Smith, Kevin M; Vicente, M Graça H

    2017-09-07

    A new synthetic method to build aryl-fused 4,4-difluoro-4-bora-3a,4a-diaza-s-indacenes (BODIPYs) is reported. The intramolecular cyclization step was completed in a short time (1-2 h) and in high yields (>90%), due to the intrinsic rigid structural conformation of the precursor BODIPY and the high reactivity of its 1,7-bromo groups. The [a]phenanthrene-fused BODIPYs 4a-c were characterized by NMR spectroscopy, HRMS, DFT calculations, and, in the case of 4a, by X-ray crystallography. Spectroscopic studies show that 4a-c strongly absorb and emit in the NIR spectral region, in the range 642-701 nm. In addition, BODIPYs 4b and 4c exhibit no toxicity in the light or dark in HEp2 cells and accumulate intracellularly in a time-dependent manner, mainly in the cell endoplasmic reticulum. These results suggest the potential use of [a]phenanthrene-fused BODIPYs as NIR bioimaging probes.

  13. 76 FR 12365 - Canaan Valley National Wildlife Refuge, Tucker and Grant Counties, WV; Final Comprehensive...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-07

    ... grassland. Refuge visitors engage in wildlife observation and photography, environmental education... observation and photography, and environmental education and interpretation. We will review and update the CCP..., build a new environmental education pavilion, and increase the number of environmental education and...

  14. 77 FR 44684 - American Woodmark Corporation, Moorefield, WV; Notice of Negative Determination on Reconsideration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-30

    ... kitchen and bath cabinetry products. Pursuant to 29 CFR 90.18(c), reconsideration may be granted under the... were not attributable to increased imports of kitchen and bath cabinetry, or articles like or directly... to a shift of production of kitchen and bath cabinetry, or articles like or directly competitive,...

  15. Characterization of Rain Attenuation and Depolarization at W/V Bands

    DTIC Science & Technology

    2015-07-30

    investigating effects of the atmosphere on electromagnetic signal propagation at W-band (81 – 86 GHz) and V-band (71 – 76 GHz). We compared modeling...parameters such as frequency, rain, temperature, and rain drop size distribution [13]. Depolarization of a propagating electromagnetic wave is usually due...Laws and Parsons Distribution (LP): mainly used when the rain rate is below 35 mm/h in continental temperate rainfall with a mean drop size spectrum

  16. 76 FR 64295 - Proposed Amendment of Class E Airspace; Huntington, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-18

    ... developed at Tri-State/Milton J Ferguson Field Airport. This action would enhance the safety and airspace... surface to support new Standard Instrument Approach Procedures developed at Tri-State/Milton J Ferguson... of that authority as it would amend Class E airspace at Tri-State/ Milton J Ferguson Field...

  17. Characterization of Rain Attenuation and Depolarization at W/V Bands

    DTIC Science & Technology

    2017-03-22

    first part covers the results from the data analyzed from the short link to examine the validity and the accuracy of the ITU-R and Silva models for...covers the results from the data analyzed from the short link (0.56 km) to examine the validity and the accuracy of the ITU-R and Silva models for rain...en. 4. L.A.R. da Silva Mello, M.S. Pontes, R.M. de Souza, and N.A. Perez Garcia (2007), “Prediction of rain attenuation in terrestrial links using

  18. 76 FR 40402 - Matthews International Corporation, Bronze Division, Kingwood, WV; Notice of Negative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-08

    ... Employment and Training Administration TA-W-72,953 Matthews International Corporation, Bronze Division... former workers of Matthews International Corporation, Bronze ] Division, Kingwood, West Virginia (subject..., 2011 (76 FR 7584). Workers were engaged in the production of cast bronze memorial products. The...

  19. 78 FR 8589 - Verizon Services Corporation, Customer Services Clerk, General Clerk, Clarksburg, WV; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-06

    ... Employment and Training Administration Verizon Services Corporation, Customer Services Clerk, General Clerk... of Verizon Services Corporation, Customer Services Clerk, General Clerk, Clarksburg, West Virginia... country the supply of services like or directly competitive with those supplied by the workers and did...

  20. WV R-EMAP STUDY: MULTIPLE-OBJECTIVE SAMPLING DESIGN FRAMEWORK

    EPA Science Inventory

    A multi-objective sampling design has been implemented through Regional Monitoring and Assessment Program (R-EMAP) support of a cooperative agreement with the state of West Virginia. Goals of the project include: 1) development and testing of a temperature-adjusted fish IBI for t...

  1. 78 FR 3964 - Request for Public Comment, Raleigh County Memorial Airport, Beckley, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-17

    ... Creek Gorge'' to a depth in excess of 600ft below the airport elevation and has no aeronautical benefit... development opportunities exist for the airport. Once released, the land will be sold and placed in a Conservation Easement, with restriction of no future development. Proposed buyer would be placing the area...

  2. 77 FR 38376 - Request for Public Comment, Raleigh County Memorial Airport, Beckley, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-27

    ... Airport Circle, Room 101, Beaver, West Virginia 25813. In addition, one copy of any comments submitted to... Airport Circle, Room 105, Beaver, West Virginia 25813. FOR FURTHER INFORMATION CONTACT: Connie...

  3. Proceedings of the Third International Workshop on Multistrategy Learning, May 23-25 Harpers Ferry, WV.

    DTIC Science & Technology

    1996-09-16

    can be Now, the agent M synthesizes complex objects of the divided into several classes depending on the model of form XY from objects X sent by B...1976) evaluated a encounters with the environment and virtually "crying out number of criteria associated with category use and they to be named" (Berlin...the Irrelevant attributes and noise other hand, tighter significance levels (e.g., a = 0.001) have left our results virtually unchanged. Bayesian

  4. 77 FR 55899 - CSX Transportation, Inc.-Discontinuance of Service Exemption-in Raleigh County, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-11

    ...) Melanie B. Yasbin, Law Offices of Louis E. Gitomer, LLC, 600 Baltimore Avenue, Suite 301, Towson, MD 21204... appropriate. Similarly, no environmental or historic documentation is required under 49 CFR 1105.6(c)(2) and...

  5. Kanawha State Forest, WV: Wildland fire fuel load assessment and geospatial distribution

    Treesearch

    Adele Fenwick; Jamie L. Schuler; Shawn Grushecky; Thomas M. Schuler; Melissa. Thomas-Van Gundy

    2014-01-01

    Fire has become a major concern along the wildland-urban interface (WUI), and there is increased awareness that fires could result in serious damage to people and property in residential areas occurring in forested landscapes. Part of the long-term strategy the West Virginia Division of Forestry outlined in the 2010 West Virginia Statewide Forest Resource Assessment...

  6. WV Kids Count Data Book: 1992 County Profiles of Child Well-Being.

    ERIC Educational Resources Information Center

    West Virginia Task Force on Children, Youth and Families, Charleston.

    In order to document the economic, social, educational, and emotional status and physical well-being of children in West Virginia, this databook provides national and state profiles, a separate minority profile, and 55 county profiles. For the state and each county, 10-year (1980-90) trend data are presented for 12 indicators: child abuse/neglect…

  7. 47 CFR 22.627 - Effective radiated power limits.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    .... Pleasant, MI, 43°34′24.1″ N. Lat. 84°46′21.1″ W. Long. 476-482 MHz482-488 MHz 488-494 MHz 494-500 MHz 500.... Lat. 77°00′15.9″ W. Long. Champaign, IL, 40°04′11.1″ N. Lat. 87°54′45.1″ W. Long. Madison, WI, 43°03′01.0″ N. Lat. 89°29′15.4″ W. Long. Parkersburg, WV, 39°20′50.3″ N. Lat. 81°33′55.5″ W. Long....

  8. 47 CFR 22.627 - Effective radiated power limits.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    .... Pleasant, MI, 43°34′24.1″ N. Lat. 84°46′21.1″ W. Long. 476-482 MHz482-488 MHz 488-494 MHz 494-500 MHz 500.... Lat. 77°00′15.9″ W. Long. Champaign, IL, 40°04′11.1″ N. Lat. 87°54′45.1″ W. Long. Madison, WI, 43°03′01.0″ N. Lat. 89°29′15.4″ W. Long. Parkersburg, WV, 39°20′50.3″ N. Lat. 81°33′55.5″ W. Long....

  9. 47 CFR 22.627 - Effective radiated power limits.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    .... Pleasant, MI, 43°34′24.1″ N. Lat. 84°46′21.1″ W. Long. 476-482 MHz482-488 MHz 488-494 MHz 494-500 MHz 500.... Lat. 77°00′15.9″ W. Long. Champaign, IL, 40°04′11.1″ N. Lat. 87°54′45.1″ W. Long. Madison, WI, 43°03′01.0″ N. Lat. 89°29′15.4″ W. Long. Parkersburg, WV, 39°20′50.3″ N. Lat. 81°33′55.5″ W. Long....

  10. 47 CFR 22.627 - Effective radiated power limits.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    .... Pleasant, MI, 43°34′24.1″ N. Lat. 84°46′21.1″ W. Long. 476-482 MHz482-488 MHz 488-494 MHz 494-500 MHz 500.... Lat. 77°00′15.9″ W. Long. Champaign, IL, 40°04′11.1″ N. Lat. 87°54′45.1″ W. Long. Madison, WI, 43°03′01.0″ N. Lat. 89°29′15.4″ W. Long. Parkersburg, WV, 39°20′50.3″ N. Lat. 81°33′55.5″ W. Long....

  11. First highly efficient and photostable E and C derivatives of 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) as dye lasers in the liquid phase, thin films, and solid-state rods.

    PubMed

    Duran-Sampedro, Gonzalo; Esnal, Ixone; Agarrabeitia, Antonia R; Bañuelos Prieto, Jorge; Cerdán, Luis; García-Moreno, Inmaculada; Costela, Angel; Lopez-Arbeloa, Iñigo; Ortiz, María J

    2014-02-24

    A new library of E- and C-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) derivatives has been synthesized through a straightforward protocol from commercially available BODIPY complexes, and a systematic study of the photophysical properties and laser behavior related to the electronic properties of the B-substituent group (alkynyl, cyano, vinyl, aryl, and alkyl) has been carried out. The replacement of fluorine atoms by electron-withdrawing groups enhances the fluorescence response of the dye, whereas electron-donor groups diminish the fluorescence efficiency. As a consequence, these compounds exhibit enhanced laser action with respect to their parent dyes, both in liquid solution and in the solid phase, with lasing efficiencies under transversal pumping up to 73 % in liquid solution and 53 % in a solid matrix. The new dyes also showed enhanced photostability. In a solid matrix, the derivative of commercial dye PM597 that incorporated cyano groups at the boron center exhibited a very high lasing stability, with the laser emission remaining at the initial level after 100 000 pump pulses in the same position of the sample at a 10 Hz repetition rate. Distributed feedback laser emission was demonstrated with organic films that incorporated parent dye PM597 and its cyano derivative. The films were deposited onto quartz substrates engraved with appropriate periodical structures. The C derivative exhibited a laser threshold lower than that of the parent dye as well as lasing intensities up to three orders of magnitude higher.

  12. Specificity of the hepatitis C virus NS3 serine protease: effects of substitutions at the 3/4A, 4A/4B, 4B/5A, and 5A/5B cleavage sites on polyprotein processing.

    PubMed Central

    Kolykhalov, A A; Agapov, E V; Rice, C M

    1994-01-01

    Cleavage at four sites (3/4A, 4A/4B, 4B/5A, and 5A/5B) in the hepatitis C virus polyprotein requires a viral serine protease activity residing in the N-terminal one-third of the NS3 protein. Sequence comparison of the residues flanking these cleavage sites reveals conserved features including an acidic residue (Asp or Glu) at the P6 position, a Cys or Thr residue at the P1 position, and a Ser or Ala residue at the P1' position. In this study, we used site-directed mutagenesis to assess the importance of these and other residues for NS3 protease-dependent cleavages. Substitutions at the P7 to P2' positions of the 4A/4B site had varied effects on cleavage efficiency. Only Arg at the P1 position or Pro at P1' substantially blocked processing at this site. Leu was tolerated at the P1 position, whereas five other substitutions allowed various degrees of cleavage. Substitutions with positively charged or other hydrophilic residues at the P7, P3, P2, and P2' positions did not reduce cleavage efficiency. Five substitutions examined at the P6 position allowed complete cleavage, demonstrating that an acidic residue at this position is not essential. Parallel results were obtained with substrates containing an active NS3 protease domain in cis or when the protease domain was supplied in trans. Selected substitutions blocking or inhibiting cleavage at the 4A/4B site were also examined at the 3/4A, 4B/5A, and 5A/5B sites. For a given substitution, a site-dependent gradient in the degree of inhibition was observed, with a 3/4A site being least sensitive to mutagenesis, followed by the 4A/4B, 4B/5A, and 5A/5B sites. In most cases, mutations abolishing cleavage at one site did not affect processing at the other serine protease-dependent sites. However, mutations at the 3/4A site which inhibited cleavage also interfered with processing at the 4B/5A site. Finally, during the course of these studies an additional NS3 protease-dependent cleavage site has been identified in the NS4B

  13. Effects of a Culturally Responsive Teaching Project on Teachers and Students in Selected Kanawha County, WV, Schools

    ERIC Educational Resources Information Center

    Hughes, Georgia K.; Cowley, Kimberly S.; Copley, Lisa D.; Finch, Nicole L.; Meehan, Merrill L.; Burns, Rebecca C.; Kusimo, Patricia S.; Keyes, Marian C.; Orletsky, Sandra R.; Holdzkom, David

    2004-01-01

    Differences in academic achievement among ethnic and socioeconomic groups, called achievement gaps, have been an issue in education for many years. Achievement gaps exist between upper- and lower-class students and between students of differing races and ethnic backgrounds. As a group, Black and Hispanic students perform less well on many…

  14. Evaluating reclamation success: the ecological consideration-proceedings of a symposium; 1990 April 23-26; Charleston, WV.

    Treesearch

    Jeanne C. Chambers; Gary L. Wade; [Editors

    1992-01-01

    Includes 10 papers from a symposium organized to review what is know about the ecological principles that will govern the ultimate success or failure of all reclamation efforts on drastically disturbed lands. The papers cover four general areas: soil biological properties and nutrient cycling; vegetation dynamics; animal recolinization; and landscape-scale processes...

  15. Superfund record of decision (EPA Region 3): Allegany Ballistics Laboratory (USNavy) Site 10, Mineral, WV, June 30, 1998

    SciTech Connect

    1998-12-01

    This decision document presents the selected remedial action for Site 10 (the Site) Groundwater at the Allegany Ballistics Laboratory (ABL), Rocket Center, West Virginia. The major components of the selected remedy are: Institutional controls, including land use restrictions imposed through appropriate administrative mechanisms to prevent groundwater use; Groundwater pumping from a minimum of three extraction wells to capture the hot spot of the VOC contaminant plume; Installation of a pipeline to transport groundwater from Site 10 to the Site 1 treatment plant; Discharge to the North Branch Potomac River; and Groundwater monitoring on a timely basis, quarterly to semi-annually, will evaluate groundwater quality, contaminant migration, and degradation for inclusion in the 5-year site reviews.

  16. Superfund Record of Decision (EPA Region 3): Allegany Ballistics Laboratory (USNavy), Operable Unit 1, Mineral, WV, February 12, 1997

    SciTech Connect

    1998-01-01

    This decision document presents the selected remedial action for Site 5 Landfill Contents and Surface Soil at the Allegany Ballistics Laboratory (ABL), Rocket Center, West Virginia. The major components of the selected remedy are: Deed notation along with property use and limited access restrictions; Installation of a composite CAP-GCL and FMC; Installation of a drainage layer utilizing a geonet; Installation of a passive landfill gas (LFG) venting system; Revegetation of the capped area; Installation of perimeter drainage system; and Post-closure requirements.

  17. Feasibility study of wood-fired cogeneration at a Wood Products Industrial Park, Belington, WV. Phase II

    SciTech Connect

    Vasenda, S.K.; Hassler, C.C.

    1992-06-01

    Customarily, electricity is generated in a utility power plant while thermal energy is generated in a heating/cooling plant; the electricity produced at the power plant is transmitted to the heating/cooling plant to power equipments. These two separate systems waste vast amounts of heat and result in individual efficiencies of about 35%. Cogeneration is the sequential production of power (electrical or mechanical) and thermal energy (process steam, hot/chilled water) from a single power source; the reject heat of one process issued as input into the subsequent process. Cogeneration increases the efficiency of these stand-alone systems by producing these two products sequentially at one location using a small additional amount of fuel, rendering the system efficiency greater than 70%. This report discusses cogeneration technologies as applied to wood fuel fired system.

  18. The search for extraterrestrial intelligence; Proceedings of the Workshop, Green Bank, WV, May 20-22, 1985

    NASA Astrophysics Data System (ADS)

    Kellermann, Kenneth I.; Seielstad, George A.

    Papers are presented on life in space and humanity on earth, the Ozma project, the evolution of strategy for SETI, the search for biomolecules in space, a symbiotic SETI search, searches in the optical portion of the spectrum, a search for SETI targets, and a Milky Way search strategy for extraterrestrial intelligence. Topics discussed include SETI observations worldwide, the ultranarrow-band SETI at Harvard/Smithsonian, the NASA SETI program, narrow-band signal detection in the SETI field test, radio astronomy aspects of the NASA SETI sky survey, and small SETI systems. Consideration is given to the nature of technological civilizations and the manifestation of intelligence implications for SETI.

  19. An Evaluation of the Merit Reading Software Program in the Calhoun County (WV) Middle/High School

    ERIC Educational Resources Information Center

    Jones, Jerry D.; Staats, William D.; Bowling, Noel; Bickel, Robert D.; Cunningham, Michael L.; Cadle, Connie

    2005-01-01

    We were asked by Merit Software to conduct a quasi-experimental research study to evaluate the effects of its reading software on middle school students. Because the No Child Left Behind Act emphasizes the importance of evidence-based interventions and has set improving students reading comprehension as a goal, we agreed to take on this project.…

  20. WV R-EMAP SMALL WATERSHED CHARACTERIZATION, CLASSIFICATION, AND ASSESSMENT FOR WEST VIRGINIA UTILIZING EMAP DESIGN AND TOOLS

    EPA Science Inventory

    A probabilistic watershed-based framework was developed to encompass wadeable streams within all three ecoregions of West Virginia, with the exclusion noted below. In Phase I of the project (year 2001), we developed and applied a probabilistic watershed-based sampling framework ...

  1. The response of tree ring δ15N to whole-watershed urea fertilization at the Fernow Experimental Forest, WV

    Treesearch

    Mark B. Burnham; Brenden E. McNeil; Mary Beth Adams; William T. Peterjohn

    2016-01-01

    Plant tissue δ15N is frequently used as a proxy for N availability and N cycle dynamics, and the δ15N signature of tree rings could potentially be used to reconstruct past changes in the N cycle due to forest disturbance or anthropogenic N deposition. However, there are substantial uncertainties regarding how effectively...

  2. Rock Physics Modeling to Constrain Petrophysical Properties in the Productive Zone of the Marcellus Shale, WV from Wireline Log Data

    NASA Astrophysics Data System (ADS)

    Morshed, S. M.; Tatham, R. H.

    2013-12-01

    A rock physics characterization based on wireline log data is proposed for constraining the petrophysical properties of the productive interval in the Marcellus Shale. The method involves two parts, 1) petrophysical interpretation of organic shale from wireline log data, and 2) rock physics modeling utilizing the interpreted log data. A petrophysical interpretation of the more radioactive interval of log data suggests that higher TOC is associated with lower clay content. This interpretation also showed that upper the part of the Marcellus Shale is clay dominated whereas the lower part is quartz dominated. Following the petrophysically interpreted data, the rock physics modeling was performed using differential effective medium (DEM) scheme in an inclusion based model to estimate the effective elastic moduli of the composites. The elastic moduli of the matrix phase in the DEM were provided with the Voigt-Reuss-Hill average for a composition of quartz and clay. Imbedded inclusions were assumed. Three types of inclusion phases were considered; a dry pore (i.e. equant pores or ellipsoidal pores), a water-wet clay pore and kerogen. Dry pores were saturated with pore fluids simulating reservoir situations with the low frequency Gassmann equations. Rock physics modeling suggests that the elastic properties of the Marcellus Shale were controlled by the interplay of clay content, kerogen content and low aspect ratio pores. Low aspect ratio pores (~1/40) also comprise the dominant pore types in the Marcellus Shale and these pores are more common in the lower part of the formation. An illustration of the DEM scheme for understanding the effect of inclusion moduli and inclusion shape to host material. Here, the host is a solid rock of 40% Quartz with clay mixture, and kerogen is the inclusion. It shows that aspect ratio of kerogen inclusion plays a significant role in this scheme; lower aspect ratio produces much lower elastic moduli than higher aspect ratios.

  3. WV R-EMAP SMALL WATERSHED CHARACTERIZATION, CLASSIFICATION, AND ASSESSMENT FOR WEST VIRGINIA UTILIZING EMAP DESIGN AND TOOLS

    EPA Science Inventory

    A probabilistic watershed-based framework was developed to encompass wadeable streams within all three ecoregions of West Virginia, with the exclusion noted below. In Phase I of the project (year 2001), we developed and applied a probabilistic watershed-based sampling framework ...

  4. Bayer Cropscience to Enhance Safeguards at Chemical Facilities in Four States to Settle Violations at W.V. Plant

    EPA Pesticide Factsheets

    WASHINGTON - The U.S. Environmental Protection Agency (EPA) and U.S. Department of Justice (DOJ) today announced a $5.6 million settlement with Bayer CropScience LP to resolve violations of federal chemical accident prevention laws at its facility i

  5. 75 FR 1806 - Draft General Management Plan and Environmental Impact Statement, New River Gorge National River, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-13

    ... other places that once populated the gorge, experience the river, and enjoy a variety of recreational... National River. SUMMARY: Pursuant to the National Environmental Policy Act of 1969, 42 U.S.C. 4332(2)(C... various management prescriptions to ensure protection, access and enjoyment of the park's resources...

  6. 26 CFR 301.7514-1 - Seals of office.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... (Nashville) Los Angeles District Manhattan District Michigan District (Detroit) Midwest District (Milwaukee.... District Director of Internal Revenue, Parkersburg, W. Va. District Director of Internal Revenue, Milwaukee...

  7. 26 CFR 301.7514-1 - Seals of office.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... (Nashville) Los Angeles District Manhattan District Michigan District (Detroit) Midwest District (Milwaukee.... District Director of Internal Revenue, Parkersburg, W. Va. District Director of Internal Revenue, Milwaukee...

  8. 76 FR 57013 - Approval and Promulgation of Air Quality Implementation Plans; West Virginia; Revised Motor...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-15

    ...; Revised Motor Vehicle Emission Budgets for the Charleston, Huntington, Parkersburg, Weirton, and Wheeling..., Huntington, Parkersburg, Weirton, and Wheeling 8-hour ozone maintenance areas. This revision amends the... Federal Register, EPA is approving the State's SIP submittal as a direct final rule without prior...

  9. 76 FR 79539 - Approval and Promulgation of Air Quality Implementation Plans; West Virginia; Revised Motor...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-22

    ...; Revised Motor Vehicle Emission Budgets for the Charleston, Huntington, Parkersburg, Weirton, and Wheeling... a direct final rule pertaining to EPA's approval of the revised motor vehicle emissions budgets for the Charleston, Huntington, Parkersburg, Weirton, and Wheeling 8-hour ozone maintenance areas....

  10. 76 FR 56975 - Approval and Promulgation of Air Quality Implementation Plans; West Virginia; Revised Motor...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-15

    ...; Revised Motor Vehicle Emission Budgets for the Charleston, Huntington, Parkersburg, Weirton, and Wheeling... Charleston, Huntington, Parkersburg, Weirton, and Wheeling 8-hour ozone maintenance areas. This revision... is approving this SIP revision to the West Virginia maintenance plans for the Charleston, Huntington...

  11. Perfluorooctanoic Acid Exposure and Cancer Outcomes in a Contaminated Community: A Geographic Analysis

    PubMed Central

    Hoffman, Kate; Shin, Hyeong-Moo; Weinberg, Janice M.; Webster, Thomas F.; Fletcher, Tony

    2013-01-01

    Background: Perfluorooctanoic acid (PFOA) has been linked to cancer in occupational mortality studies and animal toxicologic research. Objective: We investigated the relationship between PFOA exposure and cancer among residents living near the DuPont Teflon-manufacturing plant in Parkersburg, West Virginia (WV). Methods: Our analyses included incident cases of 18 cancers diagnosed from 1996 through 2005 in five Ohio (OH) counties and eight WV counties. For analyses of each cancer outcome, controls comprised all other cancers in the study data set except kidney, pancreatic, testicular, and liver cancers, which have been associated with PFOA in animal or human studies. We applied logistic regression models to individual-level data to calculate adjusted odds ratios (AORs) and confidence intervals (CIs). For the combined analysis of OH and WV data, the exposure of interest was resident water district. Within OH, geocoded addresses were integrated with a PFOA exposure model to examine the relationship between cancer odds and categories of estimated PFOA serum. Results: Our final data set included 7,869 OH cases and 17,238 WV cases. There was a positive association between kidney cancer and the very high and high serum exposure categories [AOR = 2.0 (95% CI: 1.0, 3.9) n = 9 and 2.0 (95% CI: 1.3, 3.2) n = 22, respectively] and a null association with the other exposure categories compared with the unexposed. The largest AOR was for testicular cancer with the very high exposure category [2.8 (95% CI: 0.8, 9.2) n = 6], but there was an inverse association with the lower exposure groups, and all estimates were imprecise because of small case numbers. Conclusions: Our results suggest that higher PFOA serum levels may be associated with testicular, kidney, prostate, and ovarian cancers and non-Hodgkin lymphoma. Strengths of this study include near-complete case ascertainment for state residents and well-characterized contrasts in predicted PFOA serum levels from six

  12. A watershed-based spatially-explicit demonstration of an integrated environmental modeling framework for ecosystem services in the Coal River Basin (WV, USA)

    Treesearch

    John M. Johnston; Mahion C. Barber; Kurt Wolfe; Mike Galvin; Mike Cyterski; Rajbir Parmar; Luis Suarez

    2016-01-01

    We demonstrate a spatially-explicit regional assessment of current condition of aquatic ecoservices in the Coal River Basin (CRB), with limited sensitivity analysis for the atmospheric contaminant mercury. The integrated modeling framework (IMF) forecasts water quality and quantity, habitat suitability for aquatic biota, fish biomasses, population densities, ...

  13. Category and Perceptual Interference in Second-Language Phoneme Learning: An Examination of English /w/-/v/ Learning by Sinhala, German, and Dutch Speakers

    ERIC Educational Resources Information Center

    Iverson, Paul; Ekanayake, Dulika; Hamann, Silke; Sennema, Anke; Evans, Bronwen G.

    2008-01-01

    The present study investigated the perception and production of English /w/ and /v/ by native speakers of Sinhala, German, and Dutch, with the aim of examining how their native language phonetic processing affected the acquisition of these phonemes. Subjects performed a battery of tests that assessed their identification accuracy for natural…

  14. A Watershed-based spatially-explicit demonstration of an Integrated Environmental Modeling Framework for Ecosystem Services in the Coal River Basin (WV, USA)

    EPA Science Inventory

    We demonstrate a spatially-explicit regional assessment of current condition of aquatic ecoservices in the Coal River Basin (CRB), with limited sensitivity analysis for the atmospheric contaminant mercury. The integrated modeling framework (IMF) forecasts water quality and quant...

  15. RETROFIT COSTS FOR SO2 AND NOX CONTROL OPTIONS AT 200 COAL-FIRED PLANTS, VOLUME V - SITE SPECIFIC STUDIES FOR PA, SC, TN, VA, WI, WV

    EPA Science Inventory

    The report gives results of a study, the objective of which was to significantly improve engineering cost estimates currently being used to evaluate the economic effects of applying SO2 and NOx controls at 200 large SO2-emitting coal-fired utility plants. To accomplish the object...

  16. A Watershed-based spatially-explicit demonstration of an Integrated Environmental Modeling Framework for Ecosystem Services in the Coal River Basin (WV, USA)

    EPA Science Inventory

    We demonstrate a spatially-explicit regional assessment of current condition of aquatic ecoservices in the Coal River Basin (CRB), with limited sensitivity analysis for the atmospheric contaminant mercury. The integrated modeling framework (IMF) forecasts water quality and quant...

  17. Arthurdale (WV), Its Community School, and Director Elsie Ripley Clapp (1879-1965): First New Deal Subsistence Homestead Program (1933-48).

    ERIC Educational Resources Information Center

    Parker, Franklin

    Arthurdale, in northern West Virginia, was the first New Deal subsistence homestead project. Begun in 1933, the Arthurdale settlement was created to house displaced and jobless coal mining families. Eleanor Roosevelt was very active in the Arthurdale project. At the time of the project's founding, it was attacked by some for its costliness and the…

  18. Fifty years of watershed research on the Fernow Experimental Forest, WV: effects of forest management and air pollution on hardwood forests

    Treesearch

    M.B. Adams; P.J. Edwards; J.N. Kochenderfer; F. Wood

    2004-01-01

    In 1951, stream gaging was begun on five small headwater catchments on the Fernow Experimental Forest in West Virginia, to study the effects of forest management activities, particularly timber harvesting, on water yield and quality. Results from these watersheds, and others gaged more recently, have shown that annual water yields increase in proportion to the basal...

  19. An in-use comparison of chlorhexidine gluconate 4% w/v, glycol-poly-siloxane plus methylcellulose and a liquid soap in a special care baby unit.

    PubMed

    Webster, J; Faoagali, J L

    1989-08-01

    The effectiveness and harshness of three hand-wash agents, chlorhexidine gluconate 4%, glycol-poly-siloxane gel and a bland liquid soap were studied in-use in a Special Care Baby Unit (SCBU). Each product was used for consecutive 2-week periods by the same groups of 8 health care workers among the 56 in the SCBU. The first group had normal skin, the second had 'sensitive skin' and the third group were known MRSA nasal carriers. Blood agar and methicillin mannitol salt agar were inoculated before and after hand washing and differences in colony counts calculated. Nursing activities before washing were graded from clean to dirty on an eight-point scale and correlated with before-wash colony counts. Product acceptability was assessed with a self-reporting questionnaire. Chlorhexidine was the most effective product in reducing skin microflora but users preferred to wash with the gel preparation. The sensitive-skin group achieved the best effects from washing, irrespective of the product used. Nasal carriers of MRSA recorded the lowest reduction levels of methicillin-resistant organisms but achieved the same reduction levels as the normal-skin group for other microflora. No relationship could be established between the pre-wash activity and the pre-wash colony count. The weekly MRSA colonization rate in neonates on the SCBU remained unaffected by any of the products tested.

  20. RETROFIT COSTS FOR SO2 AND NOX CONTROL OPTIONS AT 200 COAL-FIRED PLANTS, VOLUME V - SITE SPECIFIC STUDIES FOR PA, SC, TN, VA, WI, WV

    EPA Science Inventory

    The report gives results of a study, the objective of which was to significantly improve engineering cost estimates currently being used to evaluate the economic effects of applying SO2 and NOx controls at 200 large SO2-emitting coal-fired utility plants. To accomplish the object...

  1. Lipoxin A4, a 5-lipoxygenase pathway metabolite, modulates immune response during acute respiratory tularemia.

    PubMed

    Singh, Anju; Rahman, Tabassum; Bartiss, Rose; Arabshahi, Alireza; Prasain, Jeevan; Barnes, Stephen; Musteata, Florin Marcel; Sellati, Timothy J

    2017-02-01

    Respiratory infection with Francisella tularensis (Ft) is characterized by a muted, acute host response, followed by sepsis-like syndrome that results in death. Infection with Ft establishes a principally anti-inflammatory environment that subverts host-cell death programs to facilitate pathogen replication. Although the role of cytokines has been explored extensively, the role of eicosanoids in tularemia pathogenesis is not fully understood. Given that lipoxin A4 (LXA4) has anti-inflammatory properties, we investigated whether this lipid mediator affects host responses manifested early during infection. The addition of exogenous LXA4 inhibits PGE2 release by Ft-infected murine monocytes in vitro and diminishes apoptotic cell death. Tularemia pathogenesis was characterized in 5‑lipoxygenase-deficient (Alox5(-/-)) mice that are incapable of generating LXA4 Increased release of proinflammatory cytokines and chemokines, as well as increased apoptosis, was observed in Alox5(-/-) mice as compared with their wild-type counterparts. Alox5(-/-) mice also exhibited elevated recruitment of neutrophils during the early phase of infection and increased resistance to lethal challenge. Conversely, administration of exogenous LXA4 to Alox5(-/-) mice made them more susceptible to infection thus mimicking wild-type animals. Taken together, our results suggest that 5-LO activity is a critical regulator of immunopathology observed during the acute phase of respiratory tularemia, regulating bacterial burden and neutrophil recruitment and production of proinflammatory modulators and increasing morbidity and mortality. These studies identify a detrimental role for the 5-LO-derived lipid mediator LXA4 in Ft-induced immunopathology. Targeting this pathway may have therapeutic benefit as an adjunct to treatment with antibiotics and conventional antimicrobial peptides, which often have limited efficacy against intracellular bacteria. © Society for Leukocyte Biology.

  2. 75 FR 82146 - Prompt Payment Interest Rate; Contract Disputes Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-29

    ...\\ per centum per annum. ADDRESSES: Comments or inquiries may be mailed to Dorothy Dicks, Reporting Team... Accounting, Bureau of the Public Debt, Parkersburg, West Virginia 26106-1328, (304) 480-5103; Dorothy...

  3. 76 FR 38742 - Prompt Payment Interest Rate; Contract Disputes Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-01

    ..., 2011, to December 31, 2011. ADDRESSES: Comments or inquiries may be mailed to Dorothy Dicks, Reporting..., Parkersburg, West Virginia 26106-1328, (304) 480-5103; Dorothy Dicks, Reporting Team Leader,...

  4. Polyfluoroalkyl substance exposure in the Mid-Ohio River Valley, 1991-2012.

    PubMed

    Herrick, Robert L; Buckholz, Jeanette; Biro, Frank M; Calafat, Antonia M; Ye, Xiaoyun; Xie, Changchun; Pinney, Susan M

    2017-09-01

    Industrial discharges of perfluorooctanoic acid (PFOA) to the Ohio River, contaminating water systems near Parkersburg, WV, were previously associated with nearby residents' serum PFOA concentrations above US general population medians. Ohio River PFOA concentrations downstream are elevated, suggesting Mid-Ohio River Valley residents are exposed through drinking water. Quantify PFOA and 10 other per- and polyfluoroalkyl substances (PFAS) in Mid-Ohio River Valley resident sera collected between 1991 and 2013 and determine whether the Ohio River and Ohio River Aquifer are exposure sources. We measured eleven PFAS in 1608 sera from 931 participants. Serum PFOA concentration and water source associations were assessed using linear mixed-effects models. We estimated between-sample serum PFOA using one-compartment pharmacokinetics for participants with multiple samples. In serum samples collected as early as 1991, PFOA (median = 7.6 ng/mL) was detected in 99.9% of sera; 47% had concentrations greater than US population 95th percentiles. Five other PFAS were detected in greater than 82% of samples; median other PFAS concentrations were similar to the US general population. Serum PFOA was significantly associated with water source, sampling year, age at sampling, tap water consumption, pregnancy, gravidity and breastfeeding. Serum PFOA was 40-60% lower with granular activated carbon (GAC) use. Repeated measurements and pharmacokinetics suggest serum PFOA peaked 2000-2006 for participants using water without GAC treatment; where GAC was used, serum PFOA concentrations decreased from 1991 to 2012. Mid-Ohio River Valley residents appear to have PFOA, but not other PFAS, serum concentrations above US population levels. Drinking water from the Ohio River and Ohio River Aquifer, primarily contaminated by industrial discharges 209-666 km upstream, is likely the primary exposure source. GAC treatment of drinking water mitigates, but does not eliminate, PFOA exposure. Copyright

  5. Annexin A4: A novel molecular marker for gastric cancer with Helicobacter pylori infection using proteomics approach.

    PubMed

    Lin, Li-Ling; Chen, Chiung-Nien; Lin, Wei-Chou; Lee, Po-Huang; Chang, King-Jen; Lai, Yo-Ping; Wang, Jin-Town; Juan, Hsueh-Fen

    2008-04-01

    Helicobacter pylori was reported to be an important risk factor for the carcinogenesis of gastric cancer. Here, we used a proteomic approach to find differentially expressed proteins between the normal and tumor tissue of gastric cancer patients infected with H. pylori. In our results, we found annexin A4 was over-expressed in patients infected with H. pylori and was found in tumor cells, and over-expressed in gastric cancer SCM-1 cells after H. pylori infection. Ca(2+ ) can be induced by H. pylori and interact with annexin A4 Ca(2+) binding site to block the calmodulin-activated chloride conductance activation; therefore, it produces a new environment that benefits the malignant existence of H. pylori and raises the risk for gastric cancer. We also found interleuken-8 (IL-8) expression levels were increased in H. pylori infected SCM-1 cells. Combined with previous reports and our results, we summarize that the over-expression of annexin A4 in SCM-1 cells with H. pylori infection may subsequently induce IL-8 which can further cause tumor angiogenesis. In this paper, we show that annexin A4 is a potential novel molecular marker for gastric cancer with H. pylori infection, and our results may provide a new insight in the development of new anti-cancer drugs. Copyright © 2008 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. SPF-5506-A4, a new peptaibol inhibitor of amyloid beta-peptide formation produced by Trichoderma sp.

    PubMed

    Hosotani, Nobuo; Kumagai, Kazuo; Honda, Shigeyuki; Ito, Akira; Shimatani, Takuro; Saji, Ikutaro

    2007-03-01

    A new peptaibol compound, SPF-5506-A4, was isolated from the fermentation broth of Trichoderma sp. SPF-5506. The chemical structure of the 14-residue peptide was determined by MS, NMR and amino acid sequence analyses. The absolute configuration of amino acid residues in the acid hydrolysate was determined by Marfey's method. The structure of SPF-5506-A4 was established as Ac-Aib-L-Asn-L-Ile-Aib-L-Pro-L-Ser-L-Ile-Aib-L-Pro-L-Leu-L-Leu-Aib-L-Pro-L-leucinol. The compound inhibited amyloid beta-peptide formation in primary guinea pig cerebral cortex neuron cell culture dose-dependently with an IC50 of 0.1 microg/ml. Cytotoxicity was not observed at concentrations of <3 microg/ml.

  7. Freezing Baboon Red Blood Cells in the Original 800 ml Polyvinylchloride Plastic Bag With 40% W/V Glycerol and Storage at -80 C and Deglycerolization Using the IBM Code Blood Processor 2991

    DTIC Science & Technology

    1997-08-12

    primary bag with a volume of 800 ml. Each primary collection bag contains 63 ml of citrate-phosphate-dextrose-adenine (CPDA- 1) anticoagulant . After...22 C to prepare platelet-rich-plasma ( PRP ) and a red blood cell concentrate. Non-rejuvenated glycerolized red cells spun at 1248 X g for 10

  8. A Process Evaluation of the WV Smoking Cessation and Reduction in Pregnancy Treatment (SCRIPT) Dissemination Initiative: Assessing the Fidelity and Impact of Delivery for State-Wide, Home-Based Healthy Start Services.

    PubMed

    Windsor, Richard; Clark, Jeannie; Davis, Amanda; Wedeles, John; Abroms, Lorien

    2017-01-01

    Objectives Process evaluation data are essential to document the fidelity of program implementation by clinical staff and confirm patient behavior change. This report presents a process evaluation model applied to the Smoking Cessation and Reduction in Pregnancy Treatment Dissemination Initiative for the statewide, home-based West Virginia Right From The Start Project. Methods Trained RFTS Designated Care Coordinators, nurses and social workers, of 50+ primary care agencies in all 55 counties, delivered SCRIPT to Medicaid patients who smoked. Results The process evaluation defined the level of DCC delivery of seven core SCRIPT procedures to produce a Program Implementation Index: a summary performance metric. A SCRIPT PII > 0.80 was established as the RFTS adoption standard. The PII increased from 0.53 in 2004 to 0.65 in 2006-2007 to 0.77 in 2009-2010. Although the PII > 0.80 was not achieved, exposure rates were increased for all seven SCRIPT procedures. Agency and DCC turnover, a transient patient population, and recession of 2008-2010 were barriers to achieving the adoption metric and implementation of an experimental design. A quasi-experimental Stratified, Matched Comparison (C) Group Design was selected to evaluate behavioral impact differences between a RFTS-Comparison (C) Group from 2006 to 2007 and the RFTS-SCRIPT E Group from 2009 to 2010. Impact analyses of the DCC delivery of the SCRIPT Program with higher fidelity documented a statistically significant increase in the cessation rate from 4.6 % and significant reduction rate from 6.9 % for the (C) Group in 2006-2007 to 13.9 % and 11.22 % respectively for the E Group in 2009-2010. Conclusion The PEM can assist statewide, home-based prenatal care programs to improve the quality of delivery and evaluate counseling programs.

  9. Enhancing community partnerships during a public health emergency: the school-located vaccination clinics model in Kanawha County, WV during the 2009 influenza A (H1N1) pandemic.

    PubMed

    Gupta, Rahul

    2011-01-01

    Broad based community support is vital in developing a comprehensive national strategy to protect the public's health prior to, during and after a disaster such as pandemic influenza. When disaster strikes, the successful response is often dependent upon the degree of collaboration, coordination, and shared decision making occurring among a wide-ranging group of public and private stakeholders in the community. Since these preparedness and response activities must occur at a local level, the degree to which a certain community can become resilient after an event is directly dependent upon the success of the response activities. In order to protect its citizens, the Kanawha-Charleston Health Department (KCHD) led a comprehensive community based response to the 2009 Influenza A (H1N1) pandemic. By organizing a high level strategic team consisting of major community stakeholders, KCHD was able to develop broad based community support for its mitigation and countermeasure delivery strategies. The timely enhancement of the existing community partnerships enabled us to successfully conduct several response activities with local community support including school-located vaccination (SLV) clinics. We describe the process, results and challenges faced during our SLV clinics campaign which resulted in exceptionally high vaccination rates for school aged children compared to other jurisdictions across the nation. We also discuss how such partnerships can be sustained resulting in resilient communities and mention some strategies for those contemplating such partnerships in future public health emergency.

  10. Seasonal variation of artemisinin, artemisinic acid, and dihydroartemisinic acid in Brazilian, Chinese, and Swiss cultivars of Artemisia annua in WV, and effect of drying procedures on artemisinin and its precursors

    USDA-ARS?s Scientific Manuscript database

    The increased demand for artemisinin worldwide has led to the increased worldwide cultivation of Artemisia annua for the production of artemisinin. Artemisinin is a safe and effective sesquiterpene lactone effective against a range of diseases caused by protozoa (e.g., malaria, coccidiosis, leishma...

  11. 31 CFR 316.6 - Purchase of bonds.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... companies, and other agencies as had been duly qualified as issuing agents. (2) Bonds registered in names of trustees of employee savings plans. At such incorporated bank, trust company, or other agency, duly... the Bureau of the Fiscal Service, Parkersburg, West Virginia. ...

  12. 31 CFR 316.6 - Purchase of bonds.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... companies, and other agencies as had been duly qualified as issuing agents. (2) Bonds registered in names of trustees of employee savings plans. At such incorporated bank, trust company, or other agency, duly... the Bureau of the Public Debt, Parkersburg, West Virginia. ...

  13. 31 CFR 316.6 - Purchase of bonds.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... companies, and other agencies as had been duly qualified as issuing agents. (2) Bonds registered in names of trustees of employee savings plans. At such incorporated bank, trust company, or other agency, duly... the Bureau of the Public Debt, Parkersburg, West Virginia. ...

  14. 31 CFR 316.6 - Purchase of bonds.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... companies, and other agencies as had been duly qualified as issuing agents. (2) Bonds registered in names of trustees of employee savings plans. At such incorporated bank, trust company, or other agency, duly... the Bureau of the Public Debt, Parkersburg, West Virginia. ...

  15. 31 CFR 316.6 - Purchase of bonds.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... companies, and other agencies as had been duly qualified as issuing agents. (2) Bonds registered in names of trustees of employee savings plans. At such incorporated bank, trust company, or other agency, duly... the Bureau of the Public Debt, Parkersburg, West Virginia. ...

  16. 47 CFR 73.622 - Digital television table of allotments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ..., 19, *20, 22, 24c, 26, 31, 32, 46c Naples 41, 45 New Smyrna Beach *33 Ocala 31 Orange Park 10 Orlando... Parkersburg 49 Weston 6 Wheeling 32 Wisconsin Community Channel No. Appleton 27c Chippewa Falls 49c Eagle..., 22, 25c, 28, 33, 34, *35, 46, 61 Park Falls *47 Racine 48 Rhinelander 16 Superior 19 Suring 21 Wausau...

  17. 77 FR 71383 - Approval and Promulgation of Air Quality Implementation Plans; Ohio; Redesignation of the Ohio...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-30

    ... Parkersburg-Marietta area. Finally, EPA is proposing to approve the 2005 primary PM 2.5 , NO X and sulfur... modified stationary sources in an area, and section 172(c)(5) requires source permits for the construction and operation of new and modified major stationary sources anywhere in the nonattainment area. EPA...

  18. Services for Evening Students: Final Report of a Survey Conducted in the 1979 Fall Semester.

    ERIC Educational Resources Information Center

    Clovis, George A.

    An in-class survey of 1,198 students attending evening classes at Parkersburg Community College was conducted to determine: (1) the students' awareness of nine college services available during evening hours; (2) the additional services needed by evening students and the hours during which they should be provided; (3) the demographic and…

  19. 78 FR 53275 - Approval and Promulgation of Air Quality Implementation Plans; Ohio; Redesignation of the Ohio...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-29

    ... dioxide (SO 2 ), ammonia and volatile organic compounds (VOC) in the Parkersburg-Marietta area (Washington... provided ammonia and VOC emissions inventories to EPA to supplement the February 29, 2012, and April 16... 2005 NO X , SO 2 , and PM 2.5 emission inventories and 2007/2008 ammonia and VOC emission inventories...

  20. 31 CFR 351.23 - Are tables of redemption values available for bonds issued prior to May 1, 1995?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PUBLIC DEBT OFFERING OF UNITED STATES SAVINGS BONDS, SERIES EE Maturities, Redemption Values, and Investment Yields of Series EE Savings Bonds Series Ee Savings Bonds with Issue Dates Prior to May 1, 1995... Public Debt, Parkersburg, West Virginia 26106-1328. Series EE Savings Bonds With Issue Dates From May 1...

  1. Safety on a Rural Community College Campus via Integrated Communications

    ERIC Educational Resources Information Center

    Gnage, Marie Foster; Dziagwa, Connie; White, Dave

    2009-01-01

    West Virginia University at Parkersburg uses a two-way emergency system as a baseline for emergency communications. The college has found that such a system, a key component of its safety and crisis management plan, can be integrated with other communication initiatives to provide focused security on the campus.

  2. Home Start Evaluation Study.

    ERIC Educational Resources Information Center

    High/Scope Educational Research Foundation, Ypsilanti, MI.

    Case studies of eight Home Start programs are given as the third section of an evaluation study. Communities involved are Binghamton, New York; Franklin, North Carolina; Cleveland, Ohio; Harrogate, Tennessee; Houston, Texas; Weslaco, Texas; Millville, Utah; Parkersburg, West Virginia. Although each study varies in format, each describes in detail…

  3. Characterization of Molecular Factors Critical to the S100A4 (A Metastasis-Associated Protein)-Dependent Increase in Motility of Breast Cancer Cells

    DTIC Science & Technology

    2005-04-01

    Cold Spring Harbor Laboratory... Cold Spring Harbor , NY 11724 REPORT DATE: April 2005 TYPE OF REPORT: Annual Summary 20060309 15 PREPARED FOR: U.S. Army Medical Research...Ph.D. 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION Cold Spring Harbor Laboratory REPORT NUMBER Cold Spring Harbor ,

  4. Commensurate and Incommensurate Phases in the System A4A'Ir 2O 9( A=Sr, Ba; A'=Cu, Zn)

    NASA Astrophysics Data System (ADS)

    Battle, Peter D.; Blake, Graeme R.; Sloan, Jeremy; Vente, Jaap F.

    1998-02-01

    The crystal structure of Sr 4CuIr 2O 9is very sensitive to the conditions of synthesis. Prolonged heating of a commensurate trigonal sample prepared at 1120°C leads to the adoption of an incommensurate structure which can be regarded as a composite of two substructures having common unit cell parameters aand bbut different parameters c1and c2. No detectable change in chemical composition accompanies the structural transition, nor do the magnetic properties of the sample change significantly. The structure of the commensurate form has been determined from neutron powder diffraction data collected at 4.5 K (space group P321, a=9.68540(3) Å, c=8.04726(6) Å). Ir 2O 9octahedral dimers and CuO 6trigonal prisms alternate in chains parallel to z, with the Sr cations located between the chains; the Cu 2+cations are disordered within the prisms. The incommensurate form has been studied by X-ray diffraction and electron microscopy ( a=9.7020(6) Å, c1=4.0069(5) Å, c2=2.6993(4) Å). The relationship between the commensurate and incommensurate unit cells is discussed ( c˜2 c1˜3 c2). No commensurate Ba 4A'Ir 2O 9phases could be prepared, but incommensurate samples having A'=Cu, Zn showed behavior similar to that of Sr 4CuIr 2O 9.

  5. The heat shock factor A4A confers salt tolerance and is regulated by oxidative stress and the mitogen-activated protein kinases MPK3 and MPK6.

    PubMed

    Pérez-Salamó, Imma; Papdi, Csaba; Rigó, Gábor; Zsigmond, Laura; Vilela, Belmiro; Lumbreras, Victoria; Nagy, István; Horváth, Balázs; Domoki, Mónika; Darula, Zsuzsa; Medzihradszky, Katalin; Bögre, László; Koncz, Csaba; Szabados, László

    2014-05-01

    Heat shock factors (HSFs) are principal regulators of plant responses to several abiotic stresses. Here, we show that estradiol-dependent induction of HSFA4A confers enhanced tolerance to salt and oxidative agents, whereas inactivation of HSFA4A results in hypersensitivity to salt stress in Arabidopsis (Arabidopsis thaliana). Estradiol induction of HSFA4A in transgenic plants decreases, while the knockout hsfa4a mutation elevates hydrogen peroxide accumulation and lipid peroxidation. Overexpression of HSFA4A alters the transcription of a large set of genes regulated by oxidative stress. In yeast (Saccharomyces cerevisiae) two-hybrid and bimolecular fluorescence complementation assays, HSFA4A shows homomeric interaction, which is reduced by alanine replacement of three conserved cysteine residues. HSFA4A interacts with mitogen-activated protein kinases MPK3 and MPK6 in yeast and plant cells. MPK3 and MPK6 phosphorylate HSFA4A in vitro on three distinct sites, serine-309 being the major phosphorylation site. Activation of the MPK3 and MPK6 mitogen-activated protein kinase pathway led to the transcriptional activation of the HEAT SHOCK PROTEIN17.6A gene. In agreement that mutation of serine-309 to alanine strongly diminished phosphorylation of HSFA4A, it also strongly reduced the transcriptional activation of HEAT SHOCK PROTEIN17.6A. These data suggest that HSFA4A is a substrate of the MPK3/MPK6 signaling and that it regulates stress responses in Arabidopsis.

  6. NBCe1 (SLC4A4) a potential pH regulator in enamel organ cells during enamel development in the mouse.

    PubMed

    Jalali, R; Guo, J; Zandieh-Doulabi, B; Bervoets, T J M; Paine, M L; Boron, W F; Parker, M D; Bijvelds, M J C; Medina, J F; DenBesten, P K; Bronckers, A L J J

    2014-11-01

    During the formation of dental enamel, maturation-stage ameloblasts express ion-transporting transmembrane proteins. The SLC4 family of ion-transporters regulates intra- and extracellular pH in eukaryotic cells by cotransporting HCO3 (-) with Na(+). Mutation in SLC4A4 (coding for the sodium-bicarbonate cotransporter NBCe1) induces developmental defects in human and murine enamel. We have hypothesized that NBCe1 in dental epithelium is engaged in neutralizing protons released during crystal formation in the enamel space. We immunolocalized NBCe1 protein in wild-type dental epithelium and examined the effect of the NBCe1-null mutation on enamel formation in mice. Ameloblasts expressed gene transcripts for NBCe1 isoforms B/D/C/E. In wild-type mice, weak to moderate immunostaining for NBCe1 with antibodies that recognized isoforms A/B/D/E and isoform C was seen in ameloblasts at the secretory stage, with no or low staining in the early maturation stage but moderate to high staining in the late maturation stage. The papillary layer showed the opposite pattern being immunostained prominently at the early maturation stage but with gradually less staining at the mid- and late maturation stages. In NBCe1 (-/-) mice, the ameloblasts were disorganized, the enamel being thin and severely hypomineralized. Enamel organs of CFTR (-/-) and AE2a,b (-/-) mice (CFTR and AE2 are believed to be pH regulators in ameloblasts) contained higher levels of NBCe1 protein than wild-type mice. Thus, the expression of NBCe1 in ameloblasts and the papillary layer cell depends on the developmental stage and possibly responds to pH changes.

  7. 26 CFR 1.170A-4A - Special rule for the deduction of certain charitable contributions of inventory and other property.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... provisions of the Federal Food, Drug, and Cosmetic Act (as amended), and the regulations thereunder, at the..., mental, or emotional well-being, as a result of poverty or temporary distress. Examples of needy persons..., a person who temporarily lacks food or shelter (and the means to provide for it), a person who...

  8. Draft Genome Sequence of Pantoea sp. Strain A4, a Rafflesia-Associated Bacterium That Produces N-Acylhomoserine Lactones as Quorum-Sensing Molecules

    PubMed Central

    Hong, Kar-Wai; Gan, Han Ming; Low, Siew-Moon; Lee, Patrick Kok Yuen; Chong, Yee-Meng; Yin, Wai-Fong

    2012-01-01

    Pantoea sp. strain A4 is a Gram-negative bacterium isolated from the Rafflesia flower. We present here, for the first time, the genome sequence of Rafflesia-associated Pantoea sp. strain A4, which exhibited quorum-sensing activity. PMID:23144374

  9. Draft genome sequence of Pantoea sp. strain A4, a Rafflesia-associated bacterium that produces N-acylhomoserine lactones as quorum-sensing molecules.

    PubMed

    Hong, Kar-Wai; Gan, Han Ming; Low, Siew-Moon; Lee, Patrick Kok Yuen; Chong, Yee-Meng; Yin, Wai-Fong; Chan, Kok-Gan

    2012-12-01

    Pantoea sp. strain A4 is a Gram-negative bacterium isolated from the Rafflesia flower. We present here, for the first time, the genome sequence of Rafflesia-associated Pantoea sp. strain A4, which exhibited quorum-sensing activity.

  10. 26 CFR 1.170A-4A - Special rule for the deduction of certain charitable contributions of inventory and other property.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... institutionalization (such as a former prisoner or a former patient in a mental institution). (E) Definition of care of... connection with its transfer of the donated property, if: (A) The fee is small or nominal in relation to the...

  11. 26 CFR 1.170A-4A - Special rule for the deduction of certain charitable contributions of inventory and other property.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... an existing illness and includes care of the physical, mental, or emotional needs of the ill. (D... of self-care (including incapacity due to old age). A person suffering from mental illness is... person is nonhospitalized or noninstitutionalized, if the person's mental illness constitutes...

  12. 26 CFR 1.170A-4A - Special rule for the deduction of certain charitable contributions of inventory and other property.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... an existing illness and includes care of the physical, mental, or emotional needs of the ill. (D... of self-care (including incapacity due to old age). A person suffering from mental illness is... person is nonhospitalized or noninstitutionalized, if the person's mental illness constitutes...

  13. 26 CFR 1.170A-4A - Special rule for the deduction of certain charitable contributions of inventory and other property.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... an existing illness and includes care of the physical, mental, or emotional needs of the ill. (D... of self-care (including incapacity due to old age). A person suffering from mental illness is... person is nonhospitalized or noninstitutionalized, if the person's mental illness constitutes...

  14. Integrin (alpha6beta4) signals through Src to increase expression of S100A4, a metastasis-promoting factor: implications for cancer cell invasion.

    PubMed

    Kim, Tae Hyong; Kim, Hong Im; Soung, Young Hwa; Shaw, Leslie A; Chung, Jun

    2009-10-01

    Integrin alpha6beta4 is linked to cancer cell motility and invasion in aggressive and metastatic cancer cells. In this study, we showed that expression of the beta4 integrin in MDA-MB-435 cancer cells (MDA-MB-435/beta4) leads to a dramatic increase in expression of a metastasis-promoting factor, S100A4, as determined by affymetrix gene chip microarray, quantitative real-time PCR, and Western blot analysis. Alternatively, knocking down beta4 integrin expression in MDA-MB-231 breast carcinoma cells by shRNA reduced the level of S100A4 expression. The mechanism by which alpha6beta4 enhances S100A4 expression involves Src, Akt, and NFAT. We have further shown that Y1494, a tyrosine residue of the ITIM motif in the cytoplasmic domain of the beta4 integrin subunit, is essential for alpha6beta4-dependent S100A4 expression. Reduction of S100A4 expression by shRNA blocked migration, invasion, and anchorage-independent growth of MDA-MB-435/beta4, SUM-159, and MDA-MB-231 cells. These studies define a novel mechanism by which integrin alpha6beta4 promotes cancer cell motility and invasion, and provides insight into how S100A4 expression is regulated in cancer cells.

  15. The Effect of microRNAs in the Regulation of Human CYP3A4: a Systematic Study using a Mathematical Model

    NASA Astrophysics Data System (ADS)

    Wei, Zhiyun; Jiang, Songshan; Zhang, Yiting; Wang, Xiaofei; Peng, Xueling; Meng, Chunjie; Liu, Yichen; Wang, Honglian; Guo, Luo; Qin, Shengying; He, Lin; Shao, Fengmin; Zhang, Lirong; Xing, Qinghe

    2014-03-01

    CYP3A4 metabolizes more than 50% of the drugs on the market. The large inter-individual differences of CYP3A4 expression may contribute to the variability of human drug responses. Post-transcriptional regulation of CYP3A4 is poorly understood, whereas transcriptional regulation has been studied much more thoroughly. In this study, we used multiple software programs to predict miRNAs that might bind to CYP3A4 and identified 112 potentially functional miRNAs. Then a luciferase reporter system was used to assess the effect of the overexpression of each potentially functional miRNA in HEK 293T cells. Fourteen miRNAs that significantly decreased reporter activity were measured in human liver samples (N = 27) as candidate miRNAs. To establish a more effective way to analyze in vivo data for miRNA candidates, the relationship between functional miRNA and target mRNA was modeled mathematically. Taking advantage of this model, we found that hsa-miR-577, hsa-miR-1, hsa-miR-532-3p and hsa-miR-627 could significantly downregulate the translation efficiency of CYP3A4 mRNA in liver. This study used in silico, in vitro and in vivo methods to progressively screen functional miRNAs for CYP3A4 and to enhance our understanding of molecular events underlying the large inter-individual differences of CYP3A4 expression in human populations.

  16. 1. VIEW EAST, SEED EXTRACTOR BUILDING ON LEFT, IMPLEMENT BUILDING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. VIEW EAST, SEED EXTRACTOR BUILDING ON LEFT, IMPLEMENT BUILDING ON RIGHT. (see also WV-237-5, WV-237-9, WV-237-h-1, WV-237-L-1) - Parsons Nursery, Seed Extractor Building, South side of U.S. Route 219, Parsons, Tucker County, WV

  17. Final Inspection of Lactated Ringer’s Resuscitation Fluid, Intravenous Sodium Chloride Solution, and Sodium Chloride-Glucose Solution Used in the Deglycerolization of Human Red Cells Frozen With 40% W/V Glycerol, Produced by the Sterimatics EDM Reflups System and Stored for 8 Months to 2.3 Years.

    DTIC Science & Technology

    1994-09-08

    000027302908 06/28/94 P N N 121 12942 ARM2 LR1000 000027302909 06/27/94 P N N 122 12641 ARM2 LR1000 000027302910 07/06/94 P N N 123 12475 ARM2 LR1000... 12641 ARM2 LR1000 000027302910 07/06/94 P 1121 1053 PASS N/A 59 10629 ARM2 LR1000 000027302912 07/06/94 P 1123 1055 PASS N/A 235 Appendix 2.5.1

  18. 76 FR 53419 - Procurement List; Proposed Additions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-26

    .... NPA: NISH (Prime Contractor). Contracting Activity: Dept. of the Treasury/Internal Revenue Service... Fifth Avenue, Huntington, WV 55 Meridian Parkway, Martinsburg, WV 1021 National Road, Wheeling, WV NPA...

  19. 77 FR 60087 - Approval and Promulgation of Air Quality Implementation Plans; West Virginia; The 2002 Base Year...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-02

    ... 3,859 Nonroad 1 2,506 130 120 134 1,138 Onroad 86 2,667 62 44 111 1,956 Biogenic N/A 99 N/A N/A N/A...: Proposed rule. SUMMARY: EPA is proposing to approve the fine particulate matter (PM 2.5 ) 2002 base year... Parkersburg Area for the 1997 PM 2.5 National Ambient Air Quality Standard (NAAQS) SIP. EPA is proposing...

  20. 76 FR 40342 - Procurement List; Proposed Additions and Deletions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-08

    ... Center, 1540 Spring Valley Drive, Huntington, WV. NPA: Goodwill Industries of KYOWVA Area, Inc., Huntington, WV. Contracting Activity: Department of Veterans Affairs, NAC, Hines, IL. Barry S. Lineback...

  1. 6. Photo copy of photograph, (original owned by Mary Gaudineer, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Photo copy of photograph, (original owned by Mary Gaudineer, Beckley, WV, copy at National Forest Office, Elkins, WV), Don Gaudineer, 1934. CONSTRUCTION OF FERNOW EXPERIMENTAL FOREST BUNKHOUSE AND GARAGE. (see also historic photograph WV-237-13) - Parsons Nursery, Fernow Experimental Forest Residence, South side of U.S. Route 219, Parsons, Tucker County, WV

  2. PROCEEDINGS: 1991 INTERNATIONAL CONFERENCE ON MUNICIPAL WASTE COMBUSTION - VOLUME 1. SESSIONS P, 0, 1A, 2A, 3A, 4A, 6A, 6B, 9C, AND 10B

    EPA Science Inventory

    The three-volumes document 82 presentations by authors from 15 countries at the Second International Conference on Municipal Waste Combustion (MWC) in Tampa, Florida, April 16-19, 1991. The Conference fostered the exchange of current information on research concerning MWC, ash di...

  3. Synthesis and Characterization of High-Affinity 4,4-Difluoro-4-bora-3a,4a-diaza-s-indacene-Labeled Fluorescent Ligands for Human β-Adrenoceptors

    PubMed Central

    2011-01-01

    The growing practice of exploiting noninvasive fluorescence-based techniques to study G protein-coupled receptor pharmacology at the single cell and single molecule level demands the availability of high-quality fluorescent ligands. To this end, this study evaluated a new series of red-emitting ligands for the human β-adrenoceptor family. Upon the basis of the orthosteric ligands propranolol, alprenolol, and pindolol, the synthesized linker-modified congeners were coupled to the commercially available fluorophore BODIPY 630/650-X. This yielded high-affinity β-adrenoceptor fluorescent ligands for both the propranolol and alprenolol derivatives; however, the pindolol-based products displayed lower affinity. A fluorescent diethylene glycol linked propranolol derivative (18a) had the highest affinity (log KD of −9.53 and −8.46 as an antagonist of functional β2- and β1-mediated responses, respectively). Imaging studies with this compound further confirmed that it can be employed to selectively label the human β2-adrenoceptor in single living cells, with receptor-associated binding prevented by preincubation with the nonfluorescent β2-selective antagonist 3-(isopropylamino)-1-[(7-methyl-4-indanyl)oxy]butan-2-ol (ICI 118551) (J. Cardiovasc. Pharmacol.1983, 5, 430–437.) PMID:21870877

  4. The Heat Shock Factor A4A Confers Salt Tolerance and Is Regulated by Oxidative Stress and the Mitogen-Activated Protein Kinases MPK3 and MPK61[C][W][OPEN

    PubMed Central

    Pérez-Salamó, Imma; Papdi, Csaba; Rigó, Gábor; Zsigmond, Laura; Vilela, Belmiro; Lumbreras, Victoria; Nagy, István; Horváth, Balázs; Domoki, Mónika; Darula, Zsuzsa; Medzihradszky, Katalin; Bögre, László; Koncz, Csaba; Szabados, László

    2014-01-01

    Heat shock factors (HSFs) are principal regulators of plant responses to several abiotic stresses. Here, we show that estradiol-dependent induction of HSFA4A confers enhanced tolerance to salt and oxidative agents, whereas inactivation of HSFA4A results in hypersensitivity to salt stress in Arabidopsis (Arabidopsis thaliana). Estradiol induction of HSFA4A in transgenic plants decreases, while the knockout hsfa4a mutation elevates hydrogen peroxide accumulation and lipid peroxidation. Overexpression of HSFA4A alters the transcription of a large set of genes regulated by oxidative stress. In yeast (Saccharomyces cerevisiae) two-hybrid and bimolecular fluorescence complementation assays, HSFA4A shows homomeric interaction, which is reduced by alanine replacement of three conserved cysteine residues. HSFA4A interacts with mitogen-activated protein kinases MPK3 and MPK6 in yeast and plant cells. MPK3 and MPK6 phosphorylate HSFA4A in vitro on three distinct sites, serine-309 being the major phosphorylation site. Activation of the MPK3 and MPK6 mitogen-activated protein kinase pathway led to the transcriptional activation of the HEAT SHOCK PROTEIN17.6A gene. In agreement that mutation of serine-309 to alanine strongly diminished phosphorylation of HSFA4A, it also strongly reduced the transcriptional activation of HEAT SHOCK PROTEIN17.6A. These data suggest that HSFA4A is a substrate of the MPK3/MPK6 signaling and that it regulates stress responses in Arabidopsis. PMID:24676858

  5. Corrosion-Control (CC) Program SIMA (Shore Intermediate Maintenance Activity) Pilot CC (Corrosion-Control) Shop Service Test and Technical Support. Volume 2. Appendices A3, A4, A6, A8.

    DTIC Science & Technology

    1985-11-30

    protects against corrosion. The aluminum forms a galvanic coating which becomes the base for the sealing system, without which it cannot be used successfully...Formula 150 and a topcoat system. The resultant coating system protects against corrosion. The aluminum forms a galvanic coating which becomes the base...excess moisture from the surface to be protected prior to applying the corrosion-preventive compound. p Apply a thin uniform coat of corrosion-preventive

  6. Crystal structure and solvent-dependent behaviours of 3-amino-1,6-diethyl-2,5,7-trimethyl-4,4-di­phenyl-3a,4a-di­aza-4-bora-s-indacene

    PubMed Central

    Yang, Lijing; Drew, Brett; Yalagala, Ravi Shekar; Chaviwala, Rameez; Simionescu, Razvan; Lough, Alan J.; Yan, Hongbin

    2017-01-01

    In the title compound (3-amino-4,4-diphenyl-BODIPY), C28H32BN3, the central six-membered ring has a flattened sofa conformation, with one of the N atoms deviating by 0.142 (4) Å from the mean plane of the other five atoms, which have an r.m.s. deviation of 0.015 Å. The dihedral angle between the two essentially planar outer five-membered rings is 8.0 (2)°. In the crystal, mol­ecules are linked via weak N—H⋯π inter­actions, forming chains along [010]. The com­pound displays solvent-dependent behaviours in both NMR and fluorescence spectroscopy. In the 1H NMR spectra, the aliphatic resonance signals virtually coalesce in solvents such as chloro­form, di­chloro­methane and di­bromo­ethane; however, they are fully resolved in solvents such as dimethyl sulfoxide (DMSO), methanol and toluene. The excitation and fluorescence intensities in chloro­form decreased significantly over time, while in DMSO the decrease is not so profound. In toluene, the excitation and fluorescent intensities are not time-dependent. This behaviour is presumably attributed to the assembly of 3-amino-4,4-diphenyl-BODIPY in solution that leads to the formation of noncovalent structures, while in polar or aromatic solvents, the formation of these assemblies is disrupted, leading to resolution of signals in the NMR spectra. PMID:28316814

  7. Superfund Record of Decision (EPA Region 1): Fort Devens-Sudbury Training Annex (areas of contamination A4, A7, and A9), Middlesex County, MA, September 30, 1997

    SciTech Connect

    1998-01-01

    The US Army Sudbury Annex (the Annex) is a National Priorities List (NPL) site under the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA). This Record of Decision addresses past releases of contaminants to all media at area of contamination (AOC) A4-Waste Dump, and past releases to groundwater at AOC A7-Old Gravel Pit Landfill and AOC A9-Petroleum, Oil, and Lubricant (POL) Burn Area.

  8. Alterations in dopamine and serotonin uptake systems in the striatum of the weaver mutant mouse.

    PubMed

    Stotz, E H; Palacios, J M; Landwehrmeyer, B; Norton, J; Ghetti, B; Simon, J R; Triarhou, L C

    1994-01-01

    In the striatum of the homozygous weaver mutant mouse (wv/wv), dopamine content, uptake and tyrosine hydroxylase activity are decreased compared to wild-type (+/+) mice. In mice heterozygous for the weaver gene (wv/+), these dopaminergic parameters exhibit only minor reductions compared to +/+ mice. The wv/wv striatum has recently been shown to have an increase in serotonin content. In the present study, the serotonin uptake system of the weaver striatum was investigated. Synaptosomal uptake of [3H] serotonin was determined in the dorsal portion of wv/wv and +/+ striatum, and serotonin uptake sites were examined by the binding of [3H] citalopram in the striatum of wv/wv, wv/+ and +/+ mice. The dopamine uptake system was also investigated in all three genotypes via the binding of [3H] mazindol. Synaptosomal uptake of [3H] serotonin was increased by 79% in the dorsal portion of the wv/wv striatum compared to that seen in the +/+ striatum. The binding of [3H] citalopram was increased by 62% in the dorsolateral and by 111% in the dorsomedial portions of the wv/wv striatum compared to +/+. [3H] Citalopram binding in the wv/+ striatum was also higher than +/+, but this increase did not reach statistical significance. Within the wv/wv striatum, [3H] mazindol binding was almost completely absent (88-89% reduction) in the dorsal portion and severely reduced in the other striatal areas. These data support the notion that the dorsal portion of the wv/wv striatum, which has the severest reduction in dopamine uptake, is hyperinnervated by serotonin fibers.

  9. Rejuvenation and Freezing of Additive-Preserved Red Blood Cells in the 1000 ML-600 ML Polyvinyl Chloride Freezing Bay System Stored for Up to 42 Days at 4 C Prior to Rejuvenation and Glycerolization Using 40% W/V Glycerol and Storage at -80 C, Washed in the Haemonetics Blood Processor 115, and Stored at 4 C for up to 24 Hours Prior to Transfusion

    DTIC Science & Technology

    2007-11-02

    RESEARCH LABORATORY BOSTON UNIVERSITY SCHOOL OF MEDICINE 615 ALBANY STREET BOSTON, MA 02118 $f CD 14 AUGUST 1997 Reproduction in whole or in part is...containing the red cells. 14 . Close the roller clamp, turn off the shaker and equilibrate the mixture for 2 minutes. 15. Switch the Eberbach shaker on...L. > CO 0) 3 03 ř? X CO CC gi> •■=• o$s &- 5 -ob 14 in AC O 15 < Cü ü < ü > Q. O -o o r- UJ X H O CC CD u. < 2 CQ O ü V

  10. Standard Operating Procedure; Red Blood Cells Collected in the CPDA-1 800 ml Primary PVC Plastic Bag Collection System and Stored for 3 to 6 Days Prior to Glycerolization in the Primary 800 ml Bag Using 40% W/V Glycerol and Storage at -80 C, Washed in the Haemonetics Blood Processor 115, and Stored at 4 C for up to 24 Hours Prior to Transfusion

    DTIC Science & Technology

    1997-01-01

    contains 63 ml of citrate-phosphate-dextrose-adenine (CPDA-1) anticoagulant . After collection of 450 ml of blood in the primary collection bag, the unit...a non- anticoagulated blood sample for serum should be collected from the venipuncture site after the unit of whole blood is collected. The serum...hematocrit of 75 + 5 V% is prepared. All the visible plasma is removed. Ideally, a non- anticoagulated blood sample for serum should be collected from

  11. 30. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    30. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, 'tractor with cultivator operating'), photographer unknown, ca. 1938. VIEW SOUTHEAST, CULTIVATING SEEDLING TRANSPLANTS. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  12. 6. Photocopy of photograph, 1972. GRAFTON BRIDGE COLLAPSE IN AUGUST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Photocopy of photograph, 1972. GRAFTON BRIDGE COLLAPSE IN AUGUST OF 1890 (From the original collection of Miss Lois Heflin, Grafton, WV) - Northwestern Virginia Railroad, Grafton Bridge, Spanning Tygart Valley River, Grafton, Taylor County, WV

  13. 6. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #295624), D. A. Oliver, ca. 1935. VIEW SOUTHWEST. - Parsons Nursery, Cone Drying Shed, South side of U.S. Route 219, Parsons, Tucker County, WV

  14. 5. Photocopy of photograph, 1976. COAL MINERS AT ENTRANCE TO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Photocopy of photograph, 1976. COAL MINERS AT ENTRANCE TO THE RICHARD MINE (From original owned by Wade Mayfield, Dellslow, WV, 1912) - Elkins Coal & Coke Company, Richard Ovens, Deckers Creek, State Route 7-92, Dellslow, Monongalia County, WV

  15. View northwest, overview of building group: chicken house (HABS No. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View northwest, overview of building group: chicken house (HABS No. WV-267-D), wash house (267-C), Albert Thacker House (267-A), coal house (267-B) (left to right in photograph) - 3249 Cyrus Road (House), Cyrus, Wayne County, WV

  16. 28. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    28. Photo copy of photograph, (original in Forest Service Office, Elkins, WV), photographer unknown, August 1939. D. A. OLIVER WITH A TRANSPLANT BOARD. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  17. 37. Photo copy of map, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    37. Photo copy of map, (original in Forest Service Office, Elkins, WV, 'Blister Rust Survey Map), 1930. PARSONS NURSERY SITE PLAN - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  18. 6. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #246860), photographer unknown, ca. 1935. EQUIPMENT DETAIL, SEED WING REMOVER. - Parsons Nursery, Seed Extractor Building, South side of U.S. Route 219, Parsons, Tucker County, WV

  19. 3. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #292222), photographer unknown, ca. 1935. VIEW EAST, CCC CAMP PARSONS, FOREST SERVICE TRUCK STORAGE ON LEFT, WATER TANK (DEMOLISHED), MESS HALL (DEMOLISHED). (see also historic photograph WV-237-20, WV-237-35) - Parsons Nursery, Civilian Conservation Corps Garage, South side of U.S. Route 219, Parsons, Tucker County, WV

  20. Striatal dopamine innervation and receptor density: regional effects of the weaver mutation.

    PubMed

    Pullara, J M; Marshall, J F

    1989-02-20

    Mice homozygous for the autosomal recessive gene weaver (wv) exhibit a regionally specific depletion of forebrain dopamine (DA). DA is reduced approximately 70% in the dorsal striatum of homozygotes (wv/wv) relative to heterozygous (+/wv) controls while DA content in ventral striatum is relatively unchanged. The goal of the present study was to determine the regional effects of the weaver mutation on striatal DA receptors and DA uptake sites using quantitative autoradiography. Catecholamine histofluorescence was used to examine midbrain DA-containing cell bodies. Compared to behaviorally normal (+/-) littermates, the binding of [3H]spiroperidol to D2 sites was significantly increased in the dorsal but not ventral striatum of wv/wv mice. Binding of the D1 ligand, [3H]SCH23390, was significantly decreased throughout the striatum of wv/wv mice. The binding of [3H]mazindol to DA uptake sites was dramatically reduced in all wv/wv striatal regions except the ventrolateral portion. Compared to +/- littermates, wv/wv mice had far fewer fluorescent cell bodies in the substantia nigra and a less pronounced reduction of ventral tegmental area fluorescent somata. These findings support the hypothesis that heterogeneities exist in the genetic control of the mesotelencephalic DA system. The results underscore the usefulness of the weaver mouse in the study of mesostriatal sub-systems, receptor regulation, and potentially as a model of human neuropathologies that affect distinct populations of cells in the mesotelencephalic system.

  1. 75 FR 72942 - Standard Instrument Approach Procedures, and Takeoff Minimums and Obstacle Departure Procedures...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-29

    ..., Eagle River Union, LOC/DME RWY 4, Orig-A Huntington, WV, Tri-State/Milton J. Ferguson Field, ILS OR LOC RWY 12, Amdt 13 Huntington, WV, Tri-State/Milton J. Ferguson Field, RADAR-1, Amdt 7 Huntington, WV, Tri-State/Milton J. Ferguson Field, RNAV (GPS) RWY 12, Amdt 2 Effective 13 JAN 2011 Cordova, AK,...

  2. Perspectives on Obesity and Its Treatment: Health Care Providers and the General Public in Rural West Virginia and Urban Baltimore

    ERIC Educational Resources Information Center

    Menez, Steven; Cheskin, Lawrence; Geller, Gail

    2013-01-01

    Objective: To determine and compare the perspectives of the general public and health care providers (HCPs) on obesity and its treatment in rural West Virginia (WV) and Baltimore, MD. Method: Surveys were completed in both locations by the general public (WV: "n" = 200; Baltimore: "n" = 171) and HCPs (WV: "n" = 25;…

  3. Cerulean Warbler Occurrence Atlas for Military Installations

    DTIC Science & Technology

    2010-04-01

    Army Ammuniton Plant (Closed) IN NO 2009 Army IOWA ARMY AMMUNITION PLANT IA UNCERTAIN 2009 USACE J. Percy Priest Lake TN UNCERTAIN 2009 USACE J...Stonewall Jackson Lake WV UNCERTAIN 2009 USACE Summersville Lake WV no POC Army Sunflower Army Ammunition Plant KS no POC USACE Sutton Lake WV UNCERTAIN

  4. 5. Photo copy of photograph, (original in Forest Service Offices, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Photo copy of photograph, (original in Forest Service Offices, Elkins, WV), H. C. Frayer, July 1947. VIEW EAST, WELL HOUSE ON RIGHT. (see also historic photograph WV-237-M-5) - Parsons Nursery, Fernow Experimental Forest Bunkhouse, South side of U.S. Route 219, Parsons, Tucker County, WV

  5. View northeast, overview of Albert Thacker building group: chicken house ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View northeast, overview of Albert Thacker building group: chicken house (HABS No. WV-267-D), wash house (267-C), privy (HABS No. WV-268-B), and house (267-A) (left to right in photograph) - 3249 Cyrus Road (House), Cyrus, Wayne County, WV

  6. Perspectives on Obesity and Its Treatment: Health Care Providers and the General Public in Rural West Virginia and Urban Baltimore

    ERIC Educational Resources Information Center

    Menez, Steven; Cheskin, Lawrence; Geller, Gail

    2013-01-01

    Objective: To determine and compare the perspectives of the general public and health care providers (HCPs) on obesity and its treatment in rural West Virginia (WV) and Baltimore, MD. Method: Surveys were completed in both locations by the general public (WV: "n" = 200; Baltimore: "n" = 171) and HCPs (WV: "n" = 25;…

  7. 76 FR 38891 - Companies Holding Certificates of Authority as Acceptable Sureties on Federal Bonds and as...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-01

    ..., SC, SD, TN, TX, UT, VT, VA, WA, WV, WI, WY. INCORPORATED IN: Florida. ACSTAR INSURANCE COMPANY (NAIC..., RI, SC, SD, TN, TX, UT, VT, VA, WA, WV, WI, WY. INCORPORATED IN: Illinois. Aegis Security Insurance..., OR, PA, RI, SC, SD, TN, TX, UT, VT, VA, WA, WV, WI, WY. INCORPORATED IN: Pennsylvania. ALL...

  8. Cerebellar cortex development in the weaver condition presents regional and age-dependent abnormalities without differences in Purkinje cells neurogenesis.

    PubMed

    Martí, Joaquín; Santa-Cruz, María C; Hervás, José P; Bayer, Shirley A; Villegas, Sandra

    2016-01-01

    Ataxias are neurological disorders associated with the degeneration of Purkinje cells (PCs). Homozygous weaver mice (wv/wv) have been proposed as a model for hereditary cerebellar ataxia because they present motor abnormalities and PC loss. To ascertain the physiopathology of the weaver condition, the development of the cerebellar cortex lobes was examined at postnatal day (P): P8, P20 and P90. Three approaches were used: 1) quantitative determination of several cerebellar features; 2) qualitative evaluation of the developmental changes occurring in the cortical lobes; and 3) autoradiographic analyses of PC generation and placement. Our results revealed a reduction in the size of the wv/wv cerebellum as a whole, confirming previous results. However, as distinguished from these reports, we observed that quantified parameters contribute differently to the abnormal growth of the wv/wv cerebellar lobes. Qualitative analysis showed anomalies in wv/wv cerebellar cytoarchitecture, depending on the age and lobe analyzed. Such abnormalities included the presence of the external granular layer after P20 and, at P90, ectopic cells located in the molecular layer following several placement patterns. Finally, we obtained autoradiographic evidence that wild-type and wv/wv PCs presented similar neurogenetic timetables, as reported. However, the innovative character of this current work lies in the fact that the neurogenetic gradients of wv/wv PCs were not modified from P8 to P90. A tendency for the accumulation of late-formed PCs in the anterior and posterior lobes was found, whereas early-generated PCs were concentrated in the central and inferior lobes. These data suggested that wv/wv PCs may migrate properly to their final destinations. The extrapolation of our results to patients affected with cerebellar ataxias suggests that all cerebellar cortex lobes are affected with several age-dependent alterations in cytoarchitectonics. We also propose that PC loss may be regionally

  9. The effect of taste masking agents on in situ gelling pectin formulations for oral sustained delivery of paracetamol and ambroxol.

    PubMed

    Miyazaki, Shozo; Kubo, Wataru; Itoh, Kunihiko; Konno, Yasuhiro; Fujiwara, Mariko; Dairaku, Masatake; Togashi, Mitsuo; Mikami, Ryozo; Attwood, David

    2005-06-13

    The aim of this study was to examine the influence of polyhydric alcohols (taste masking agents) on the rheological properties of in situ gelling pectin formulations and on the in vitro and in vivo release of paracetamol and ambroxol from these formulations. Gelation of orally administered pectin solutions containing calcium in complexed form occurred on release of calcium in the acidic environment of the stomach. Inclusion of 10% (w/v) sorbitol in 2% (w/v) pectin sols reduced the viscosity and ensured Newtonian flow properties. Xylitol and mannitol in similar concentrations were less effective in reducing viscosity; sucrose increased viscosity and caused non-Newtonian flow. The in vitro release of paracetamol from 2% (w/v) pectin gels formulated with 10% (w/v) of sorbitol, erythritol, xylitol or mannitol, and of ambroxol from 2% (w/v) pectin gels containing 10% (w/v) sorbitol, followed diffusion-controlled kinetics. Pectin gels (2%, w/v) containing sorbitol (10%, w/v) sustained the release of paracetamol in the rat stomach and bioavailabilities of approximately 90% of those from an orally administered paracetamol syrup were achieved. Sustained release of ambroxol from in situ gelling formulations was achieved with pectin concentrations of 1.5 and 1% (w/v) and a sorbitol concentration of 10% (w/v).

  10. Methyl 2-(1a,4a-dimethyl-2,8-dioxo-2,3,4,4a,5,6,7,8-octa­hydro-1aH-1-oxacyclo­propa[d]naphthalen-7-yl)acrylate

    PubMed Central

    Tebbaa, Mohamed; Benharref, Ahmed; Daran, Jean Claude; Mellouki, Fouad; Berraho, Moha

    2012-01-01

    The title compound, C16H20O5, was synthesized from ilicic acid [2-(8-hy­droxy-4a,8-dimethyl­deca­hydro­naphthalen-2-yl)acrylic acid], which was isolated from the chloro­form extract of the aerial part of Inula viscose (L) Aiton [or Dittrichia viscosa­ (L) Greuter]. The molecule is built up from two fused six-membered rings, the epoxidized six-membered ring adopts a half-chair conformation while the other ring displays a perfect chair conformation. The crystal structure features C—H⋯O hydrogen bonds. PMID:22347009

  11. Methyl 2-(1a,4a-dimethyl-2,8-dioxo-2,3,4,4a,5,6,7,8-octa-hydro-1aH-1-oxacyclo-propa[d]naphthalen-7-yl)acrylate.

    PubMed

    Tebbaa, Mohamed; Benharref, Ahmed; Daran, Jean Claude; Mellouki, Fouad; Berraho, Moha

    2012-02-01

    The title compound, C(16)H(20)O(5), was synthesized from ilicic acid [2-(8-hy-droxy-4a,8-dimethyl-deca-hydro-naphthalen-2-yl)acrylic acid], which was isolated from the chloro-form extract of the aerial part of Inula viscose (L) Aiton [or Dittrichia viscosa- (L) Greuter]. The molecule is built up from two fused six-membered rings, the epoxidized six-membered ring adopts a half-chair conformation while the other ring displays a perfect chair conformation. The crystal structure features C-H⋯O hydrogen bonds.

  12. An assessment of the ocular safety of inactive excipients following sub-tenon injection in rabbits.

    PubMed

    Younis, Husam S; Shawer, Mohannad; Palacio, Kimberly; Gukasyan, Hovhannes J; Stevens, Greg J; Evering, Winston

    2008-04-01

    This work characterized the safety and toleration of inactive excipients following sub-Tenon (ST) administration. Rabbits were anesthetized and eyes received an ST injection of the following test excipients: carboxy methylcellulose (CMC; low [90 kDa], mid [250 kDa], and high [700 kDa] molecular weight [MW], 0.25%-1.0% w/v), polysorbate 80 (0.02 and 0.2% w/v), polyethylene glycol 3350 (PEG; 0.2 and 1.0% w/v), poloxamer 188 (0.01 and 0.25% w/v), poloxamer 182 (2% w/v), benzyl alcohol (BA; 4% w/v), benzalkonium chloride (BAC; 0.02%, 0.04%, and 0.05% w/v), and methylcellulose (MC; 0.25% w/v). After a 1-week observation period for clinical signs of ocular tolerability, the animals were euthanized and eyes were collected for histologic examination. The ocular tolerability of the tested excipients were ranked as follows from the innocuous to most deleterious: saline approximately PEG (1% w/v) approximately polysorbate 80 (0.2% w/v) > CMC (0.25% w/v, 90 kDa) > MC (0.25% w/v) approximately poloxomer 188 (0.25% w/v) approximately sodium citrate (pH 9) BAC (0.05% w/v) > CMC (0.5% w/v, 700 kDa) > poloxomer 182 (2% w/v) > BA (4% w/v). Clinical signs of ocular irritation were limited to redness and chemosis observed with most test excipients. The BA excipient also produced corneal opacity. Microscopic findings included histiocytic infiltration (BAC, BA, CMC, MC, and poloxamer 188), heterophilic inflammation (BA, CMC, and poloxamer 182), and edema (BAC, BA, CMC, and poloxamer 182) in episcleral tissue. The severity of the clinical and hisopathologic effects increased with the concentration of the test excipients administered. This research has evaluated the safety profile of inactive excipients that may be used to formulate new chemical entities for the treatment of ocular disease following a ST injection.

  13. PATCH - STS-33/51-L (TEACHER IN SPACE)

    NASA Image and Video Library

    1985-08-02

    S85-38312 (September 1985) --- Logo designed for use by the 10 finalists in NASA’s Teacher in Space Project, who were at JSC for training and orientation the week of July 8–12, 1985. They are David M. Marquart, Boise High, Boise, Idaho; Michael W. Metcalf, Hazen Union School, Hardwick, Vermont; Judith Marie Garcia, Thomas Jefferson School for Science and Technology, Alexandria, Virginia; Peggy J. Lathlaen, Westwood Elementary, Friendswood, Texas; Niki Mason Wenger, Vandevender Junior High, Parkersburg, West Virginia; Barbara R. Morgan, McCall-Donnelly Elementary, McCall, Idaho; Kathleen Anne Beres, Kenwood High, Baltimore, Maryland; Richard A. Methia, New Bedford High, New Bedford, Mass.; Sharon Christa McAuliffe, Concord High, Concord, New Hampshire; and Robert S. Foerster, Cumberland Elementary School, West Lafayette, Indiana. Photo credit: NASA

  14. Development of In Vitro Isolated Perfused Porcine Skin Flaps for Study of Percutaneous Absorption of Xenobiotics

    DTIC Science & Technology

    1985-11-01

    intercellular space, yet the stratum corneum remained intact., By 24 hours, classical pyknosis occurred with shrinkage of the nucleus and condensation of...the viable eriod of this preparation. Based on basic biochemical irinciples (28), it is our hypothesis that incorporation of amino acids or short...organizations. I I L.! .~C .. . .... I bT’: t (uI [ o- jor ~ U ~ WV ~-rd -N WV V WVVV W’J 11 WJ "* -WV ~WJ 4 TABLE OF CONTENTS Abstract

  15. Predictive thermal inactivation model for effects and interactions of temperature, NaCl, sodium pyrophosphate and sodium lactate on Listeria monocytogenes in ground beef

    USDA-ARS?s Scientific Manuscript database

    The effects and interactions of heating temperature (60 to 73.9C), salt (0.0 to 4.5% w/v), sodium pyrophosphate (0.0 to 0.5% w/v), and sodium lactate (0.0 to 4.5% w/v) on the heat resistance of a four-strain mixture of Listeria monocytogenes in 75% lean ground beef were examined. Meat samples in st...

  16. 30 CFR 36.3 - Consultation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., 765 Technology Drive, Triadelphia, WV 26059, to discuss with qualified MSHA personnel proposed mobile... MINING PRODUCTS APPROVAL REQUIREMENTS FOR PERMISSIBLE MOBILE DIESEL-POWERED TRANSPORTATION...

  17. 5. VIEW FROM SLIGHTLY FARTHER DOWN SERVICE ROAD, LOOKING SOUTHEAST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. VIEW FROM SLIGHTLY FARTHER DOWN SERVICE ROAD, LOOKING SOUTHEAST AT ELECTRICITY SUPPLY BUILDING, LABORATORY, AND OFFICE. - Standard Lime & Stone Quarry, County Route 27, Millville, Jefferson County, WV

  18. 12. TRANSMISSION GEARING SHOWING RELATION TO SEGMENT GEAR ON WATERWHEEL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. TRANSMISSION GEARING SHOWING RELATION TO SEGMENT GEAR ON WATERWHEEL william E. Barrett, photographer, 1973 (copy negative) - Thomas Shepherd's Grist Mill, High Street Vicinity, Shepherdstown, Jefferson County, WV

  19. 7. William E. Barrett, Photographer, August 1975. LOG PONDS LOOKING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. William E. Barrett, Photographer, August 1975. LOG PONDS LOOKING WEST FROM POWERHOUSE ROOF. TRANSFORMER SHED IN FOREGROUND. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  20. 42 CFR 37.2 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...), located within the Centers for Disease Control and Prevention (CDC). Within NIOSH, the Division of Respiratory Disease Studies (DRDS), 1095 Willowdale Road, Morgantown, WV 26505, formerly called the...

  1. 30 CFR 18.81 - Field modification of approved (permissible) equipment; application for approval of modification...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MOTOR-DRIVEN MINE EQUIPMENT AND ACCESSORIES... and Certification Center, 765 Technology Drive, Triadelphia, WV 26059. (b) Proposed modifications...

  2. 30 CFR 18.81 - Field modification of approved (permissible) equipment; application for approval of modification...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MOTOR-DRIVEN MINE EQUIPMENT AND ACCESSORIES... and Certification Center, 765 Technology Drive, Triadelphia, WV 26059. (b) Proposed modifications...

  3. An EWMA chart for sample range of Weibull data using weighted variance method

    NASA Astrophysics Data System (ADS)

    Atta, Abdu. M. A.; Yahaya, Sharipah Soaad Syed; Zain, Zakiyah; Ali, Hazlina

    2016-10-01

    This article proposes new EWMA chart in observing process standard deviation or dispersion with sample range of Weibull data using weighted variance method (WV). This control chart, called Weighted Variance EWMA sample range WV-EWMASR chart hereafter. The proposed WV-EWMASR chart compared with standard EWMASR of [7], skewness correction R chart (SC-R) suggested by[3]and Weighted Variance R chart (WV-R) proposed by [2], in the case of Type I and Type II errors when the data generated from Weibull distribution. Optimal parameters λ and k of the proposed WV-EWMASR and standard EWMASR are obtained via simulation using SAS program 9.4. The proposed WV-EWMASR control chart reduces to the standard EWMASR control chart of [7] when the process follow symmetric distribution. The proposed WV-EWMASR control chart has less Type I error than the standard EWMASR, SC-R and WV-R control charts, for Weibull distribution data. In case of Type II error, the proposed WV-EWMASR control chart is closer to EWMA chart with the exact limits than the standard EWMASR in [7].

  4. Predicting sleep apnoea syndrome from heart period: a time-frequency wavelet analysis.

    PubMed

    Roche, F; Pichot, V; Sforza, E; Court-Fortune, I; Duverney, D; Costes, F; Garet, M; Barthélémy, J C

    2003-12-01

    Heart rate fluctuations are a typical finding during obstructive sleep apnoea, characterised by bradycardia during the apnoeic phase and tachycardia at the restoration of ventilation. In this study, a time-frequency domain analysis of the nocturnal heart rate variability (HRV) was evaluated as the single diagnostic marker for obstructive sleep apnoea syndrome (OSAS). The predictive accuracy of time-frequency HRV variables (wavelet (Wv) decomposition parameters from level 2 (Wv2) to level 256 (Wv256)) obtained from nocturnal electrocardiogram Holter monitoring were analysed in 147 consecutive patients aged 53.8+/-11.2 yrs referred for possible OSAS. OSAS was diagnosed in 66 patients (44.9%) according to an apnoea/hypopnoea index > or = 10. Using receiver-operating characteristic curves analysis, the most powerful predictor variable was Wv32 (W 0.758, p<0.0001), followed by Wv16 (W 0.729, p<0.0001) and Wv64 (W 0.700, p<0.0001). Classification and Regression Trees methodology generated a decision tree for OSAS prediction including all levels of Wv coefficients, from Wv2 to Wv256 with a sensitivity reaching 92.4% and a specificity of 90.1% (percentage of agreement 91.2%) with this nonparametric analysis. Time-frequency parameters calculated using wavelet transform and extracted from the nocturnal heart period analysis appeared as powerful tools for obstructive sleep apnoea syndrome diagnosis.

  5. First records of Nocomis biguttatus (Hornyhead Chub) from West Virginia discovered in museum voucher specimens

    USGS Publications Warehouse

    Welsh, Stuart; Cincotta, Daniel A.; Starnes, Wayne C.

    2013-01-01

    Specimens of Nocomis biguttatus (Hornyhead Chub) from South Fork Hughes River (Little Kanawha River drainage, WV) were discovered in two museum lots at the North Carolina Museum of Natural Sciences. These accessions, collected in 1960 and 1966, represent an addition to the state fauna and are the first distribution records for this species from the Appalachian Plateau, WV

  6. 77 FR 76415 - Approval and Promulgation of Air Quality Implementation Plans; West Virginia; Redesignation of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-28

    ...; Redesignation of the West Virginia Portion of the Huntington-Ashland, WV-KY-OH 1997 Annual Fine Particulate... Department of Environmental Protection (WVDEP) requested that the West Virginia portion of the Huntington- Ashland, WV-KY-OH fine particulate matter (PM 2.5 ) nonattainment area (``Huntington-Ashland Area''...

  7. 78 FR 45937 - Final Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-30

    ...-based studies: Community map repository Community address Mason County, West Virginia, and Incorporated... Mason Office of the Mayor, 656 2nd Street, Mason, WV 25260. Town of New Haven Town of New Haven City Hall, 218 5th Street, New Haven, WV 25265. Unincorporated Areas of Mason County... Mason County...

  8. 77 FR 38384 - Qualification of Drivers; Exemption Applications; Vision

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-27

    ...) Delmas C. Bergdoll (WV) Kenneth J. Bernard (LA) Allen G. Bors (NE) Brad T. Braegger (UT) John E. Breslin... (WV) Larry L. Jarvis (VA) Michael S. Johannsen (IA) Charles E. Johnston (MO) Harry L. Jones (OH) Mearl... L. Paraf (IL) Ronald M. Price (MD) John P. Raftis (FL) Scott D. Russell (WI) Alton M. Rutherford (FL...

  9. View southeast, overview of building group: coal house (HABS No. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View southeast, overview of building group: coal house (HABS No. WV-267-B), large tree, Albert Thacker House (267-A), wash house (267-C), Eustace Chadwick House (268-A) (on lot to south), chicken house (267-D), and small tree (left to right in photograph) - 3249 Cyrus Road (House), Cyrus, Wayne County, WV

  10. Case Study: Gilmer County High School, Glenville, W. Va.

    ERIC Educational Resources Information Center

    Southern Regional Education Board, Atlanta, GA.

    A group of dedicated teachers in Gilmer County High School, Glenville, West Virginia (WV), worked with school administrators to make far-reaching changes to prepare all students for further study and the workplace. With their experiences from High Schools That Work workshops and help from a WV Department of Education representative, educators…

  11. 75 FR 63475 - Radio Broadcasting Services; AM or FM Proposals To Change The Community of License

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... COMMISSION Radio Broadcasting Services; AM or FM Proposals To Change The Community of License AGENCY: Federal Communications Commission. ACTION: Notice. SUMMARY: The following applicants filed AM or FM proposals to change..., From CRAIGSVILLE, WV, To WEBSTER SPRINGS, WV; ENTRAVISION HOLDINGS, LLC, Station KVVA-FM, Facility...

  12. 31. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    31. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, 'seed bed grader in operation'), D. A. Oliver, November 3, 1937. VIEW SOUTHEAST, REMOVING SEEDLINGS FOR SHIPPING. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  13. 29. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    29. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #292218, 'Planting with 10 ft. transplant board'), D. A. Oliver, 1934. VIEW EAST, FIRMING EARTH BEFORE REMOVING TRANSPLANT BOARD FROM NEWLY TRANSPLANTED SEEDLINGS. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  14. 25. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    25. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #248333, 'Tree nurseries-seed bed preparation'), D. A. Oliver, 1930. VIEW SOUTHEAST, STORAGE SHED (DEMOLISHED), POPLAR SEEDLINGS, SHADED SEEDLING BEDS ON RIGHT. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  15. 40 CFR 81.349 - West Virginia.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., 2006 Attainment Putnam County August 10, 2006 Attainment Huntington-Ashland, WV-KY Cabell County... Nonattainment. Huntington-Ashland, WV-KY-OH: Cabell County 12/28/12 Attainment. Mason County (part) 12/28/12..., which appears in the Finding Aids section of the printed volume and at www.fdsys.gov. ...

  16. 40 CFR 81.349 - West Virginia.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... County August 10, 2006 Attainment Huntington-Ashland, WV-KY Cabell County October 16, 2006 Attainment.... Huntington-Ashland, WV-KY-OH: Cabell County Nonattainment. Mason County (part) Nonattainment. Graham Tax... printed volume and at www.fdsys.gov. ...

  17. 7. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #246865, 'Drying racks'), D. A. Oliver, 1934. FURNISHING DETAIL, DRYING RACKS. - Parsons Nursery, Cone Drying Shed, South side of U.S. Route 219, Parsons, Tucker County, WV

  18. 39. Photo copy of site plan, (original in Forest Service ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    39. Photo copy of site plan, (original in Forest Service Office, Elkins, WV, 'Parsons Nursery Special Use Permit, West Virginia Department of Natural Resources'), 1969. PARSONS NURSERY SITE PLAN. CORROLATES TO PARSONS NURSERY AT TIME OF FLOOD, NOVEMBER, 1985. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  19. Passing on a Culture: West Virginia Traditional Musical Heritage and the Allegheny Echoes Programme

    ERIC Educational Resources Information Center

    Swain, Leila Ryland

    2010-01-01

    Allegheny Echoes is a summer programme of instruction and performance of music and poetry held in Marlinton, WV. The Bing Brothers learned their traditional music from the Hammons family of Pocahontas County, WV, in an informal setting of friendship and collaboration. The Hammons family was recorded in the 1970s by Alan Jabbour and others; the…

  20. 27. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    27. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #292219, 'Tree nurseries-transplanting-transplanting beds'), D. A. Oliver, 1934. VIEW SOUTHWEST, TRANSPLANT SHED AND MAN WITH TRANSPLANT BOARD. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  1. 14. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #333469, 'Tree nurseries-seed bed preparation'), D. A. Oliver, November 1936. VIEW NORTHEAST, ORIGINAL WASH HOUSE, GARAGE (DEMOLISHED), WORKSHOP/WAREHOUSE, AND NURSERY OFFICE. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  2. 16. Photocopy of photograph, (original in Forest Service Office, Elkins, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. Photocopy of photograph, (original in Forest Service Office, Elkins, WV, photo #302581, 'Tree nurseries-Broad view, C. C. Corps project'), D. A. Oliver, May 1935. AERIAL VIEW SOUTH. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  3. 77 FR 53842 - West Virginia Resource Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-04

    ... meetings will be held on September 17, 2012, and if necessary to complete business, also on September 21... National Forest Supervisor's Office, 200 Sycamore Street, Elkins, WV 26241. Written comments should be sent... inspect comments received at Monongahela National Forest, 200 Sycamore Street, Elkins, WV 26241....

  4. 7. Photo copy of blue print sheet, (original in Forest ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Photo copy of blue print sheet, (original in Forest Service Office, Elkins, WV), George W. Root, draftsman, July, 1931. MAIN FLOOR PLAN SHOWING JOIST FRAMING, FOUNDATION PLAN, MAIN FLOOR PLAN, SECOND FLOOR PLAN, END ELEVATION AT SLOUGH. - Parsons Nursery, Packing Building, South side of U.S. Route 219, Parsons, Tucker County, WV

  5. 13. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #333464, 'Tree nurseries-seed bed preparation'), D. A. Oliver, November 1936. VIEW SOUTHEAST, WORKSHOP/WAREHOUSE, ORIGINAL WASH HOUSE, NURSERY OFFICE, NURSERY MANAGER'S RESIDENCE, GARAGE (DEMOLISHED), PUMP HOUSE, AND FERNOW EXPERIMENTAL FOREST RESIDENCE. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  6. 18. Photocopy of original postcard, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. Photocopy of original postcard, (original in Forest Service Office, Elkins, WV, 'U. S. Forest Nursery with CCC Camp in Background-Parsons, W. Va.'), photographer unknown, ca. 1936. AERIAL VIEW EAST, ORIGINAL WASH HOUSE, WORKSHOP/WAREHOUSE, TWO EQUIPMENT BUILDINGS (DEMOLISHED) IN FOREGROUND, CCC CAMP PARSONS IN BACKGROUND. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  7. 17. Photocopy of photograph, (original in Forest Service Office, Elkins, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. Photocopy of photograph, (original in Forest Service Office, Elkins, WV, photo #302580, 'View of Parsons Nursery, Monongahela National Forest'), D. A. Oliver, May 1935. AERIAL VIEW EAST. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  8. 35. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    35. Photo copy of photograph, (original in Forest Service Office, Elkins, WV), photographer unknown, ca. 1936. VIEW SOUTHEAST, CCC CAMP PARSONS, FOREST SERVICE TRUCK STORAGE GARAGE, OIL HOUSE (DEMOLISHED), RECREATION HALL (DEMOLISHED). - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  9. 32. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    32. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #285197, 'reforestation-planting crew'), D. W. Beck, April 1933. REFORESTATION CAMP, CANAAN MOUNTAIN, MESS HALL AND COOKS. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  10. 33. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    33. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #267207, '15 man planting crew 5-9-32'), photographer unknown, May 1932. REFORESTATION CAMP, CANAAN MOUNTAIN, PLANTING CREW. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  11. 26. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. Photo copy of photograph, (original in Forest Service Office, Elkins, WV), photographer unknown, ca. 1936. VIEW NORTHWEST, GARAGE (DEMOLISHED), NURSERY MANAGER'S GARAGE AND RESIDENCE, AND PACKING BUILDING, TRANSPLANT SHEDS AND PLOW IN FOREGROUND. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  12. Case Study: Effect of Handrim Diameter on Performance in a Paralympic Wheelchair Athlete

    ERIC Educational Resources Information Center

    Costa, Gabriel Brizuela; Rubio, Miguel Polo; Belloch, Salvador Llana; Soriano, Pedro Perez

    2009-01-01

    This study, with a top T-52 class athlete, determines the relationship between stroke frequency (SF) and push time (PT) and wheelchair velocity (Wv) using different handrim diameters (HD) and the effect of different HDs on the athlete's heart rate (HR) and blood lactate (LACT) at competition speeds. Wv shows a linear-direct relationship with SF…

  13. Case Study: Effect of Handrim Diameter on Performance in a Paralympic Wheelchair Athlete

    ERIC Educational Resources Information Center

    Costa, Gabriel Brizuela; Rubio, Miguel Polo; Belloch, Salvador Llana; Soriano, Pedro Perez

    2009-01-01

    This study, with a top T-52 class athlete, determines the relationship between stroke frequency (SF) and push time (PT) and wheelchair velocity (Wv) using different handrim diameters (HD) and the effect of different HDs on the athlete's heart rate (HR) and blood lactate (LACT) at competition speeds. Wv shows a linear-direct relationship with SF…

  14. 5. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #298181), D. A. Oliver, 1934. LOWER FLOOR, LOOKING WEST, SEED EXTRACTOR. - Parsons Nursery, Seed Extractor Building, South side of U.S. Route 219, Parsons, Tucker County, WV

  15. 23. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    23. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #248336, 'Tree nurseries-seed bed seeding machine'), D. A. Oliver, 1930. VIEW WEST, SEEDING MACHINE. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  16. 22. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #244025, 'seed planter'), D. A. Oliver, 1930. VIEW EAST, FRONT OF WORKSHOP/WAREHOUSE, SEED BED PLANTER. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  17. 4. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #298180, 'seed extracting equipment'), D. A. Oliver, 1934. LOWER FLOOR, LOOKING WEST, SEED EXTRACTOR. - Parsons Nursery, Seed Extractor Building, South side of U.S. Route 219, Parsons, Tucker County, WV

  18. 4. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #302582, 'Insect/disease control'), D. A. Oliver, May 1935. VIEW NORTHEAST. - Parsons Nursery, Packing Building, South side of U.S. Route 219, Parsons, Tucker County, WV

  19. 75 FR 20597 - Radio Broadcasting Services; AM or FM Proposals To Change the Community of License

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-20

    ...- 20100329AFI, From NEW MARTINSVILLE, WV, To VIENNA, WV; LOUT, JAMES M, Station NEW, Facility ID 170971, BMPH..., FL, To ORANGE PARK, FL; WOMAN'S WORLD BROADCASTING, INC., Station WTSH-FM, Facility ID 7043, BPH-20091113ACH, From ARAGON, GA, To ROCKMART, GA; WORLD RADIO LINK, INCORPORATED, Station KMVV, Facility ID...

  20. Electrospinning and Superhydrophobic Materials

    DTIC Science & Technology

    2015-04-01

    20 Figure 15 SEM images of fibres electrospun from 10% w/v Pellethane solutions containing 1% w/v TiO2 with a 20 gauge...electrospun from (left) 10% w/v Pellethane solutions containing 1% w/v TiO2 with a 24 gauge needle at flow rates of 50 µL/min (left), and 25 µL/min (right...containing 5% w/v TiO2 with a 20 gauge needle at flow rates of (a) 75 µL/min, (b) 50 µL/min, (c) 25 µL/min, and (d) 10 µL/min. Light grainy spots on

  1. Increasing alcohol yield by selected yeast fermentation of sweet sorghum. I. Evaluation of yeast strains for ethanol production

    SciTech Connect

    de Mancilha, I.M.; Pearson, A.M.; Waller, J.; Hogaboam, G.J.

    1984-01-01

    A study was conducted for the purpose of evaluating and selecting yeast strains for their ability to produce ethanol using sweet sorghum juice as the substrate. Stalks of sweet sorghum were obtained by cutting off the tops and stripping away the leaves. Fermentation media were prepared by diluting or adding dextrose to the sorghum juice to give a sugar concentration of either 10% (w/v) or 20% (w/v). All yeast strains were first tested in 10% (w/v) total sugar medium. Those strains showing more than 90% sugar conversion efficiency were further tested in 20% (w/v) total sugar medium. Active cultures for inoculation were prepared by growing the yeast strains on the fermentation medium (10% (w/v) total sugar) for 24 h. Then the cultures were added to the fermentation media at a rate of 2%.

  2. The effect of bioleaching on sewage sludge pyrolysis.

    PubMed

    Chen, Zhihua; Hu, Mian; Cui, Baihui; Liu, Shiming; Guo, Dabin; Xiao, Bo

    2016-02-01

    The effects of bioleaching on sewage sludge pyrolysis were studied. Sewage sludge was treated by bioleaching with solid concentrations of 6% (w/v), 8% (w/v), 10% (w/v). Results showed that bioleaching treatment could modify the physicochemical properties of sewage sludge and enhance the metals removal. The optimum removal efficiencies of heavy metals were achieved with solid concentration of 6% (w/v) bioleaching treatment: Cu, 73.08%; Zn, 78.67%; Pb, 24.65%; Cd, 79.46%. The characterization results of thermogravimetric analysis (TGA) showed that the bioleached sewage sludge with a 6% (w/v) solid concentration treatment was the easiest to decompose. Pyrolytic experiments of bioleached sewage sludge were performed in a laboratory-scale fixed bed reactor. Results indicated that bioleaching treatment greatly influenced the product yields and gas composition.

  3. Space-borne observations of aerosol - cloud relations for cloud systems of different heights

    NASA Astrophysics Data System (ADS)

    Stathopoulos, S.; Georgoulias, A. K.; Kourtidis, K.

    2017-01-01

    Here, we examine the aerosol - cloud relations over three major urban clusters of China, representative of three different climatic regimes, under different water vapor conditions and cloud heights, using Aerosol Optical Depth at 550 nm (AOD), Cloud Fraction (CC), Cloud Optical Depth (COD), Water Vapor (WV) and Cloud Top Pressure (CTP) data from the MODIS instrument. Over all regions and for all seasons, CC is found to increase with increasing AOD, WV and cloud height. Aerosols, at low WV environments and under constant CTP, have less impact on CC than at high WV environments. Furthermore, AOD has a varying influence on COD depending on CTP. Finally, COD is found to increase with height for low and middle height clouds, and with increasing AOD, especially at low AOD. Our results demonstrate that the role of WV in the observed satellite-based aerosol - cloud relations is significant for all cloud heights.

  4. West Virginia Full-Scale Solar Energy Team Growing the Mountain State Energy Economy by Reaching our Full Solar Potential

    SciTech Connect

    Inc., Geostellar,

    2012-02-15

    The WV Team will design and demonstrate a complete set of systems and processes for automating the identification of residential and light commercial solar opportunities, evaluating project finance options, securing permits and arranging for interconnections to the utility grid. These operations will be supported by the predictive qualification and feasibility of residential and light commercial solar energy opportunities in WV based on the current solar LCOE and potential state-wide policy initiatives. Through the WV Department of Commerce and its Division of Energy, the WV Team will coordinate with all 55 county development authorities in West Virginia, as well as a number of local and municipal authorities responsible for zoning and building code ordinances to support and implement a statewide, integrated set of regulations and administrative services. Additionally the WV Team will work with the State administration and legislature to develop incentives that will promote the financing of residential and light commercial solar projects.

  5. Optimization of γ-amino butyric acid production in a newly isolated Lactobacillus brevis.

    PubMed

    Binh, Tran Thi Thanh; Ju, Wan-Taek; Jung, Woo-Jin; Park, Ro-Dong

    2014-01-01

    An isolate from kimchi, identified as Lactobacillus brevis, accumulated γ-aminobutyric acid (GABA), a major inhibitory neurotransmitter, in the culture medium. Optimal culture conditions for growth of L. brevis and production of GABA were 6 % (w/v) l-glutamic acid, 4 % (w/v) maltose, 2 % (w/v) yeast extract, 1 % (w/v) NaCl, 1 % (w/v) CaCl2, 2 g Tween 80/l, and 0.02 mM pyridoxal 5′-phosphate at initial pH 5.25 and 37 °C. GABA reached 44.4 g/l after 72 h cultivation with a conversion rate 99.7 %, based on the amount (6 %) of l-glutamic acid added. GABA was purified using ion exchange column chromatography with 70 % recovery and 97 % purity.

  6. Intradermal testing of horses with and without insect bite hypersensitivity in The Netherlands using an extract of native Culicoides species.

    PubMed

    Sloet van Oldruitenborgh-Oosterbaan, Marianne M; van Poppel, Miriam; de Raat, Inge J; van den Boom, Robin; Savelkoul, Huub F J

    2009-10-01

    Intradermal tests using a Culicoides nubeculosus extract have proven unreliable for diagnosis of equine insect bite hypersensitivity (IBH) in the Netherlands. The aim of this study was to evaluate the diagnostic value of an extract derived from the Dutch species C. obsoletus and C. pulicaris. Thirteen pairs of horses were tested, each pair consisting of one horse with IBH and the other a healthy control. Each horse was injected intradermally with 0.1 mL of three concentrations of Culicoides whole body extract (1 : 1000 w/v, 1 : 10,000 w/v and 1 : 25,000 w/v), histamine solution (0.01 mg/mL, positive control) and phosphate-buffered saline (negative control). Skin responses were evaluated after 30 min and at 1, 4 and 24 h. At all time points the absolute wheal diameter elicited by Culicoides extract 1 : 1000 w/v was significantly larger (P < 0.01) in the IBH horses than in the control horses. Using the 1 : 10,000 w/v extract the difference was significant at 1, 4 and 24 h and using the 1 : 25,000 w/v extract only at 24 h. The relative wheal diameter was greater in IBH than in control horses at all concentrations and time points except at 0.5 h for the 1 : 10,000 w/v and 1 : 25,000 w/v concentrations. At the 1 : 1000 w/v concentration, the sensitivity and specificity was 92% using the relative wheal diameter. These results indicate that intradermal testing using 1 : 1000 w/v concentration Culicoides extracts relevant to the locality provides useful support for a clinical diagnosis of equine insect hypersensitivity.

  7. Identification of a novel multiple kinase inhibitor with potent antiviral activity against influenza virus by reducing viral polymerase activity

    SciTech Connect

    Sasaki, Yutaka; Kakisaka, Michinori; Chutiwitoonchai, Nopporn; Tajima, Shigeru; Hikono, Hirokazu; Saito, Takehiko; Aida, Yoko

    2014-07-18

    Highlights: • Screening of 50,000 compounds and subsequent lead optimization identified WV970. • WV970 has antiviral effects against influenza A, B and highly pathogenic viral strains. • WV970 inhibits viral genome replication and transcription. • A target database search suggests that WV970 may bind to a number of kinases. • KINOMEscan screening revealed that WV970 has inhibitory effects on 15 kinases. - Abstract: Neuraminidase inhibitors are the only currently available influenza treatment, although resistant viruses to these drugs have already been reported. Thus, new antiviral drugs with novel mechanisms of action are urgently required. In this study, we identified a novel antiviral compound, WV970, through cell-based screening of a 50,000 compound library and subsequent lead optimization. This compound exhibited potent antiviral activity with nanomolar IC{sub 50} values against both influenza A and B viruses but not non-influenza RNA viruses. Time-of-addition and indirect immunofluorescence assays indicated that WV970 acted at an early stage of the influenza life cycle, but likely after nuclear entry of viral ribonucleoprotein (vRNP). Further analyses of viral RNA expression and viral polymerase activity indicated that WV970 inhibited vRNP-mediated viral genome replication and transcription. Finally, structure-based virtual screening and comprehensive human kinome screening were used to demonstrate that WV970 acts as a multiple kinase inhibitor, many of which are associated with influenza virus replication. Collectively, these results strongly suggest that WV970 is a promising anti-influenza drug candidate and that several kinases associated with viral replication are promising drug targets.

  8. Reliability and validity of heart rate variability threshold assessment during an incremental shuttle-walk test in middle-aged and older adults

    PubMed Central

    Dourado, V.Z.; Guerra, R.L.F.

    2013-01-01

    Studies on the assessment of heart rate variability threshold (HRVT) during walking are scarce. We determined the reliability and validity of HRVT assessment during the incremental shuttle walk test (ISWT) in healthy subjects. Thirty-one participants aged 57 ± 9 years (17 females) performed 3 ISWTs. During the 1st and 2nd ISWTs, instantaneous heart rate variability was calculated every 30 s and HRVT was measured. Walking velocity at HRVT in these tests (WV-HRVT1 and WV-HRVT2) was registered. During the 3rd ISWT, physiological responses were assessed. The ventilatory equivalents were used to determine ventilatory threshold (VT) and the WV at VT (WV-VT) was recorded. The difference between WV-HRVT1 and WV-HRVT2 was not statistically significant (median and interquartile range = 4.8; 4.8 to 5.4 vs 4.8; 4.2 to 5.4 km/h); the correlation between WV-HRVT1 and WV-HRVT2 was significant (r = 0.84); the intraclass correlation coefficient was high (0.92; 0.82 to 0.96), and the agreement was acceptable (-0.08 km/h; -0.92 to 0.87). The difference between WV-VT and WV-HRVT2 was not statistically significant (4.8; 4.8 to 5.4 vs 4.8; 4.2 to 5.4 km/h) and the agreement was acceptable (0.04 km/h; -1.28 to 1.36). HRVT assessment during walking is a reliable measure and permits the estimation of VT in adults. We suggest the use of the ISWT for the assessment of exercise capacity in middle-aged and older adults. PMID:23369974

  9. Factors affecting mycelial biomass and exopolysaccharide production in submerged cultivation of Antrodia cinnamomea using complex media.

    PubMed

    Lin, En-Shyh; Chen, Yueh-Hsiang

    2007-09-01

    Submerged cultures were used to identify growth-limiting nutrients by Antrodia cinnamomea strains. The mycelial biomass and EPS production by A. cinnamomea BCRC 35396 were markedly higher than other A. cinnamomea strains. A relatively high C/N ratio was favorable for both the mycelial growth (5.41 g/l) and EPS production (0.55 g/l); the optimum ratio was 40. The glucose was available utilized preferentially for mycelial growth, rather than for EPS production. Flushing the culture medium with nitrogen had a stimulating effect on both mycelial growth and EPS production. In addition, peptone, yeast extract and malt extract appeared to be important and significant component for EPS production. Phosphate ion, magnesium ion and thiamine were probably not essential for mycelial growth. By optimizing the effects of additional nutrition, the results showed that 5% (w/v) glucose, 0.8% (w/v) peptone, 0.8% (w/v) yeast extract, 0.8% (w/v) malt extract, 0.03% (w/v) KH2PO4, 0.1% (w/v) MgSO4 .7H2O and 0.1% (w/v) thiamine could lead to the maximum production of EPS (1.36 g/l).

  10. Enhanced Urban Landcover Classification for Operational Change Detection Study Using Very High Resolution Remote Sensing Data

    NASA Astrophysics Data System (ADS)

    Jawak, S. D.; Panditrao, S. N.; Luis, A. J.

    2014-11-01

    This study presents an operational case of advancements in urban land cover classification and change detection by using very high resolution spatial and multispectral information from 4-band QuickBird (QB) and 8-band WorldView-2 (WV-2) image sequence. Our study accentuates quantitative, pixel based, image difference approach for operational change detection using very high resolution pansharpened QB and WV-2 images captured over San Francisco city, California, USA (37° 44" 30N', 122° 31" 30' W and 37° 41" 30° N ,122° 20" 30' W). In addition to standard QB image, we compiled three multiband images from eight pansharpened WV-2 bands: (1) multiband image from four traditional spectral bands, i.e., Blue, Green, Red and near-infrared 1 (NIR1) (henceforth referred as "QB equivalent WV-2"), (2) multiband image from four new spectral bands, i.e., Coastal, Yellow, Red Edge and NIR2 (henceforth referred as "new band WV-2"), and (3) multiband image consisting of four traditional and four new bands (henceforth referred as "standard WV-2"). All the four multiband images were classified using support vector machine (SVM) classifier into four most abundant land cover classes, viz, hard surface, vegetation, water and shadow. The assessment of classification accuracy was performed using random selection of 356 test points. Land cover classifications on "standard QB" image (kappa coeffiecient, κ = 0.93), "QB equivalent WV-2" image (κ = 0.97), and "new band WV-2" image (κ = 0.97) yielded overall accuracies of 96.31 %, 98.03 % and 98.31 %, respectively, while "standard WV-2" image (κ = 0.99) yielded an improved overall accuracy of 99.18 %. It is concluded that the addition of four new spectral bands to the existing four traditional bands improved the discrimination of land cover targets, due to increase in the spectral characteristics of WV-2 satellite. Consequently, to test the validity of improvement in classification process for implementation in operational change

  11. Perspectives on obesity and its treatment: health care providers and the general public in rural West Virginia and urban Baltimore.

    PubMed

    Menez, Steven; Cheskin, Lawrence; Geller, Gail

    2013-12-01

    To determine and compare the perspectives of the general public and health care providers (HCPs) on obesity and its treatment in rural West Virginia (WV) and Baltimore, MD. Surveys were completed in both locations by the general public (WV: n = 200; Baltimore: n = 171) and HCPs (WV: n = 25; Baltimore: n = 15). BMI (body mass index) ≥ 30 (WV: n = 94; Baltimore: n = 58) was associated with a stronger belief in the heritability of obesity and with the ability to control obesity by controlling food cost, compared with those with normal BMI (WV: n = 42; Baltimore: n = 57). Those with a high school education (WV: n = 112; Baltimore: n = 113) were less likely to agree that obesity is a problem in the community and that proper diet and exercise are realistic expectations, compared with those with at least some higher education. Perspectives of HCPs differed significantly from the general public in both locations. Many differences in perspective on obesity exist between WV and Baltimore, within both populations, and between HCPs and the general public in both settings. A better understanding of patient views is important for effective obesity management. HCPs must consider each patient's level of understanding when discussing management and consequences of obesity. More time spent with patients who have less insight into their obesity may improve patient adherence with treatment and overall patient outcomes.

  12. Soluble copolymer of wasp venom with human albumin for venom immunotherapy.

    PubMed

    Gewurz, A; Grammer, L C; Shaughnessy, M A; Patterson, R

    1986-03-01

    Polymerization of allergens decreases allergenicity while retaining immunogenicity, as we have demonstrated for ragweed, grass, and tree pollens. We have also polymerized bee venom with human albumin to form soluble, high-molecular-weight copolymers that are immunogenic in rabbits. We now have prepared a soluble wasp venom-albumin polymer (WVAP), molecular weight greater than or equal to 240,000 daltons, by glutaraldehyde treatment and Sephacryl S-300 column fractionation. Rabbits immunized with WVAP produced IgG to both WVAP and wasp venom (WV), as measured by ELISA. IgG against WVAP was totally inhibitable by a mixture of WV and albumin, demonstrating both retention of native antigens and absence of new antigenic determinants in WVAP. IgG against WV in serum from patients receiving maintenance doses of WV immunotherapy was inhibited by WVAP. In summary, we have synthesized a soluble, high-molecular-weight copolymer of WV that retains the immunogenicity of native WV, contains no new antigenic determinants, and has potential value in the treatment of patients with WV anaphylaxis.

  13. Cellulase and Xylanase Production by Penicillium echinulatum in Submerged Media Containing Cellulose Amended with Sorbitol

    PubMed Central

    Todero Ritter, Carla Eliana; Camassola, Marli; Zampieri, Denise; Silveira, Mauricio Moura; Dillon, Aldo José Pinheiro

    2013-01-01

    The present work investigated the use of sorbitol as a soluble carbon source, in association with cellulose, to produce cellulases and xylanases in submerged cultures of Penicillium echinulatum 9A02S1. Because cellulose is an insoluble carbon source, in cellulase production, there are some problems with rheology and oxygen transfer. The submerged fermentations containing media composed of 0, 0.25, 0.5, 0.75, and 1% (w/v) sorbitol and cellulose that were added at different times during the cultivation; 0.2% (w/v) soy bran; 0.1% (w/v) wheat bran; and a solution of salts. The highest filter paper activity (FPA) (1.95  ±  0.04 IU·mL−1) was obtained on the seventh day in the medium containing 0.5% (w/v) sorbitol and 0.5% (w/v) cellulose added 24 h after the start of cultivation. However, the CMCases showed an activity peak on the sixth day (9.99 ± 0.75 IU·mL−1) in the medium containing 0.75% (w/v) sorbitol and 0.75% (w/v) cellulose added after 12 h of cultivation. The xylanases showed the highest activity in the medium with 0.75% (w/v) sorbitol and 0.25% (w/v) cellulose added 36 h after the start of cultivation. This strategy enables the reduction of the cellulose concentration, which in high concentrations can cause rheological and oxygen transfer problems. PMID:24058733

  14. An Assessment of Worldview-2 Imagery for the Classification Of a Mixed Deciduous Forest

    NASA Astrophysics Data System (ADS)

    Carter, Nahid

    Remote sensing provides a variety of methods for classifying forest communities and can be a valuable tool for the impact assessment of invasive species. The emerald ash borer (Agrilus planipennis) infestation of ash trees (Fraxinus) in the United States has resulted in the mortality of large stands of ash throughout the Northeast. This study assessed the suitability of multi-temporal Worldview-2 multispectral satellite imagery for classifying a mixed deciduous forest in Upstate New York. Training sites were collected using a Global Positioning System (GPS) receiver, with each training site consisting of a single tree of a corresponding class. Six classes were collected; Ash, Maple, Oak, Beech, Evergreen, and Other. Three different classifications were investigated on four data sets. A six class classification (6C), a two class classification consisting of ash and all other classes combined (2C), and a merging of the ash and maple classes for a five class classification (5C). The four data sets included Worldview-2 multispectral data collection from June 2010 (J-WV2) and September 2010 (S-WV2), a layer stacked data set using J-WV2 and S-WV2 (LS-WV2), and a reduced data set (RD-WV2). RD-WV2 was created using a statistical analysis of the processed and unprocessed imagery. Statistical analysis was used to reduce the dimensionality of the data and identify key bands to create a fourth data set (RD-WV2). Overall accuracy varied considerably depending upon the classification type, but results indicated that ash was confused with maple in a majority of the classifications. Ash was most accurately identified using the 2C classification and RD-WV2 data set (81.48%). A combination of the ash and maple classes yielded an accuracy of 89.41%. Future work should focus on separating the ash and maple classifiers by using data sources such as hyperspectral imagery, LiDAR, or extensive forest surveys.

  15. Formulation and thermal sterile stability of a less painful intravenous clarithromycin emulsion containing vitamin E.

    PubMed

    Lu, Yan; Wang, YanJiao; Tang, Xing

    2008-01-04

    The purpose of this study is to develop a less painful intravenous clarithromycin emulsion (ClaE) and investigate its thermal sterile stability. The formulation of ClaE is composed of clarithromycin 0.25% (w/v), vitamin E 5% (w/v), medium chain triglyceride (MCT) 10% (w/v), egg lecithin 1.0% (w/v), Cremophor EL-40 (EL-40) 2% (w/v), Pluronic F-68 (F-68) 0.2% (w/v), Tween80 0.2% (w/v), glycerol 2.5% (w/v) and L-cysteine 0.05% (w/v) in water. High-pressure homogenization, photon correlation spectroscopy (PCS) and electrophoretic light scattering (ELS) technology, light microscopy and high-performance liquid chromatography (HPLC) methods were used in the preparation and evaluation of ClaE. Investigation of thermal sterile stability included the effects of different thermal sterile methods, thermal sterile time, drug concentrations and pH values. Sterilization in a 100 degrees C rotating water bath for 30 min was finally adopted as the sterilization method. The drug remaining was 98.6% and 96.5%, respectively, before and after thermal sterilization. Moreover, the pH value, particle size distribution (PSD), zeta-potential and entrapment efficiency (EE) of ClaE after sterilization were 7.95, 213.6 nm, -22.29 mV and 96.35%, respectively. This showed that ClaE had sufficient physicochemical stability to resist the sterilization process. Tests using animal models demonstrated that there was a marked pain reduction following the injection of ClaE compared with clarithromycin solution. Overall, ClaE described in this paper may be very suitable for industrial-scale production and clinical application.

  16. Optimization of bacteriocin production by Lactobacillus plantarum ST13BR, a strain isolated from barley beer.

    PubMed

    Todorov, Svetoslav Dimitrov; van Reenen, Carol Ann; Dicks, Leon Milner Theodore

    2004-06-01

    The cell-free supernatant containing bacteriocin ST13BR, produced by Lactobacillus plantarum ST13BR, inhibits the growth of L. casei, Pseudomonas aeruginosa, Enterococcus faecalis, Klebsiella pneumoniae and Escherichia coli. Based on tricine-SDS-PAGE, bacteriocin ST13BR is 10 kDa in size. Complete inactivation or significant reduction in bacteriocin activity was observed after treatment with Proteinase K, trypsin and pronase, but not with catalase or alpha-amylase. Low bacteriocin activity (200 AU/ml) was recorded in BHI medium, M17 broth, 10% (w/v) soy milk, and 2% and 10% (w/v) molasses, despite good growth. Maximal bacteriocin activity (6,400 AU/ml) was recorded after 23 h in MRS broth, but only at 30 degrees C. Tween 80 in MRS broth increased bacteriocin production by more than 50%. Meat extract or yeast extract as sole nitrogen source, or a combination of the two (1 : 1) in MRS broth, stimulated bacteriocin production (6,400 AU/ml). Only 50% activity (3,200 AU/ml) was recorded with tryptone as sole nitrogen source, whereas a combination of tryptone, meat extract and yeast extract yielded 6,400 AU/ml. Bacteriocin production was not stimulated by the addition of glucose at 2.0% w/v (3,200 AU/ml), nor 2% (w/v) fructose, sucrose, lactose or mannose, respectively (800 AU/ml). Activity levels less than 200 AU/ml were recorded in the presence of 0.05% to 0.5% (w/v) maltose. Maximal bacteriocin production (6,400 AU/ml) was recorded in the presence of 2% (w/v) maltose. Maltose at 4.0% (w/v) led to a 50% reduction of bacteriocin activity. The presence of 1.0% (w/v) and higher KH(2)PO(4), or glycerol at 0.2% (w/v) suppressed bacteriocin production.

  17. Response surface methodology for optimizing the fermentation medium of Clostridium butyricum.

    PubMed

    He, G Q; Kong, Q; Ding, L X

    2004-01-01

    Strains of Clostridium butyricum have been increasingly used as probiotics for both animals and humans. The aim of this study was to develop a growth medium for cultivating C. butyricum ZJUCB using a statistical methodology. Response surface methodology (RSM) was used to evaluate the effects of variables, namely the concentrations of the glucose, pectin, soyabean cake extract, casein, corn steep flour, ammonium sulphate, sodium bicarbonate and the medium initial pH. A fractional factorial design was applied to study the main factors that affected the growth of a probiotic strain of C. butyricum currently preserved in our lab and the central composite experimental design was adopted to derive a statistical model for optimizing the composition of the fermentation medium. The experimental results showed that the optimum fermentation medium for the growth of C. butyricum was composed of 2% glucose (w/v), 0.5% pectin (w/v), 0.2% casein (w/v), 3.98% soyabean cake extract, 0.1% (NH4)2SO4 (w/v), 0.124% NaHCO3 (w/v), 0.37% corn steep flour (w/v), 0.02% MnSO4 H2O (w/v), 0.02% MgSO4 7H2O (w/v) and 0.002% CaCl2 (w/v) at pH 7.5. After incubating 24 h in the optimum fermentation medium, the populations of the viable organisms were estimated to be 10(9) CFU ml(-1). In the present study, we report the optimization of a growth medium that produced increased yields using statistical approach. The use of bacteria as a probiotic is showing increasing potential. The development of a growth medium that has a high yield is an obvious need, and the approach to optimizing a growth medium is innovative.

  18. Flame Driving of Longitudinal Instabilities in Liquid Fueled Dump Combustors.

    DTIC Science & Technology

    1987-07-01

    W NJMflmpYA J Nu M vrpl~ Z v -d 71. lU2 wv wwswv wu wu Wwu WV VWiIw% u l WV. W~ W6 W.- 0. E 4-4 CO 0 0 140 4).. td -4 𔃾 040 00 0~~~~~- Q*0 ( 0 ( V 0...Excitation at 385 Hz. ft..• % ŕ % % ,% % -, • - %.. ... ’: ft .. . ... t -.. %. .- 6, k.. .k~ .%, J% 0 f 69 H4Z 0 *00l0O0 X fo 6 7 ez A fo 85 NX HzJ x

  19. Metallothionein-mediated neuroprotection in genetically engineered mouse models of Parkinson's disease

    PubMed Central

    Ebadi, Manuchair; Brown-Borg, Holly; Refaey, Hesham El; Singh, Brij B.; Garrett, Scott; Shavali, Shaik; Sharma, Sushil K.

    2013-01-01

    Parkinson's disease is characterized by a progressive loss of dopaminergic neurons in the substantia nigra zona compacta, and in other sub-cortical nuclei associated with a widespread occurrence of Lewy bodies. The cause of cell death in Parkinson's disease is still poorly understood, but a defect in mitochondrial oxidative phosphorylation and enhanced oxidative and nitrative stresses have been proposed. We have studied controlwt (C57B1/6), metallothionein transgenic (MTtrans), metallothionein double gene knock (MTdko), α-synuclein knock out (α-synko), α-synuclein–metallothionein triple knock out (α-syn–MTtko), weaver mutant (wv/wv) mice, and Ames dwarf mice to examine the role of peroxynitrite in the etiopathogenesis of Parkinson's disease and aging. Although MTdko mice were genetically susceptible to 1, methyl, 4-phenyl, 1,2,3,6-tetrahydropyridine (MPTP) Parkinsonism, they did not exhibit any overt clinical symptoms of neurodegeneration and gross neuropathological changes as observed in wv/wv mice. Progressive neurodegenerative changes were associated with typical Parkinsonism in wv/wv mice. Neurodegenerative changes in wv/wv mice were observed primarily in the striatum, hippocampus and cerebellum. Various hallmarks of apoptosis including caspase-3, TNFα, NFκB, metallothioneins (MT-1, 2) and complex-1 nitration were increased; whereas glutathione, complex-1, ATP, and Ser(40)-phosphorylation of tyrosine hydroxylase, and striatal 18F-DOPA uptake were reduced in wv/wv mice as compared to other experimental genotypes. Striatal neurons of wv/wv mice exhibited age-dependent increase in dense cored intra-neuronal inclusions, cellular aggregation, proto-oncogenes (c-fos, c-jun, caspase-3, and GAPDH) induction, inter-nucleosomal DNA fragmentation, and neuro-apoptosis. MTtrans and α-Synko mice were genetically resistant to MPTP-Parkinsonism and Ames dwarf mice possessed significantly higher concentrations of striatal coenzyme Q10 and metallothioneins (MT 1, 2

  20. Procedural Guide for Designation Surveys of Ocean Dredged Material Disposal Sites.

    DTIC Science & Technology

    1981-01-01

    zones ’re generally recognized: the inner, middle, and jutcr coo, t nenta ,’ zones. The inner irone extends from shore nut to a bo1th ,! 20 )T meters. As...material in a mortar to obtain single grains. If a porcelain or iron pestle is required, only up-and-down motions are used. Carbonate and ferruginous...Sulfate Solution (mixed 100:1:1 just before use) (I) 2% (w/v) NaIC0 3 in 0.1 N NaOH (2) 2% (w/v) KNa Tartrate in distilled HO (3) 1% (w/v) CuS0 4 in

  1. 50. INTERIOR VIEW OF PACKING LINE WHERE ALL THE NAIL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    50. INTERIOR VIEW OF PACKING LINE WHERE ALL THE NAIL BOXES ARE FORMED, FILLED WITH NAILS AND SEALED; NOTE THESE ARE FIFTY-POUND BOXES - LaBelle Iron Works, Thirtieth & Wood Streets, Wheeling, Ohio County, WV

  2. 32. Credit JTL. Exterior transformer bank; note lightning arrestors removed ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    32. Credit JTL. Exterior transformer bank; note lightning arrestors removed from pad and smaller arrestors installed on transformers and in area near air switches. - Dam No. 4 Hydroelectric Plant, Potomac River, Martinsburg, Berkeley County, WV

  3. 77 FR 8276 - Agency Information Collection Activities: Proposed Collection; Comments Requested: Certificate of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-14

    ... instructions or additional information, please contact Tracey Robertson, Acting Chief, Federal Firearms Licensing Center, 244 Needy Road, Martinsburg, WV 25405 or via email at tracey.robertson@atf.gov...

  4. 45. William E. Barrett, Photographer, August 1975. EARLY STEAM GENERATING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    45. William E. Barrett, Photographer, August 1975. EARLY STEAM GENERATING UNIT USED TO PRODUCE ELECTRICITY FOR MANUFACTURING OPERATIONS AND FOR THE TOWN OF RAINELLE. STEAM ENGINE IS A HAMILTON CORLISS. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  5. 35. Credit JTL. Third floor, side view of Monitor Dustless ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    35. Credit JTL. Third floor, side view of Monitor Dustless Receiving Separator, by Huntley, Cranson and Hammond, (Silver Creek NY) capacity of 100 barrels/day. - Bunker Hill Mill, County Route 26, Bunker Hill, Berkeley County, WV

  6. 21. Photocopy of photograph, photographer: The Thomas Studios, Huntington, date ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. Photocopy of photograph, photographer: The Thomas Studios, Huntington, date unknown. View northwest, rear elevation completed building. - Veterans Administration Medical Center, Building No. 1, Spring Valley Drive, Huntington, Cabell County, WV

  7. 19. Photocopy of photograph, photographer: The Thomas Studios, Huntington, May ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. Photocopy of photograph, photographer: The Thomas Studios, Huntington, May 4, 1932. View east front elevation during construction. - Veterans Administration Medical Center, Building No. 1, Spring Valley Drive, Huntington, Cabell County, WV

  8. 9. INTERIOR VIEW OF EYE PRESS AREA; TO LEFT IS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. INTERIOR VIEW OF EYE PRESS AREA; TO LEFT IS A TWO-BAY SLOTTED TYPE FURNACE, TO CENTER IS EYE PRESS, TO RIGHT IS CURCULAR SAW - Warwood Tool Company, Foot of Nineteenth Street, Wheeling, Ohio County, WV

  9. 75 FR 13486 - Application(s) for Duty-Free Entry of Scientific Instruments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-22

    ..., WV 26506. Instrument: Electron Microscope. Manufacturer: JEOL, Japan. Intended Use: The instrument... domestic manufacturers of this type of electron microscope. Application accepted by Commissioner of Customs... 13617. Instrument: Electron Microscope. Manufacturer: FEI, Czech Republic. Intended Use: This...

  10. 34. VIEW OF COFFERDAM USED IN DAM CAPPING OPERATIONS. NOTE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    34. VIEW OF COFFERDAM USED IN DAM CAPPING OPERATIONS. NOTE BARGE AT RIGHT DUMPING FILL DIRT TO INCREASE WATER TIGHTNESS OF COFFER DAM, c. 1918. - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  11. 31 CFR 353.1 - Official agencies.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... half), OH, PA, WV (northern panhandle). Federal Reserve Bank of Richmond, P.O. Box 27622, Richmond, VA 23261 Richmond, Atlanta AL, DC, FL, LA (southern half), MD, MS (southern half), NC, SC, TN (eastern...

  12. 31 CFR 352.13 - Fiscal agents.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., PA, WV (northern panhandle). Federal Reserve Bank of Richmond, P.O. Box 27622, Richmond, VA 23261 Richmond, Atlanta AL, DC, FL, LA (southern half), MD, MS (southern half), NC, SC, TN (eastern half), VA,...

  13. 31 CFR 315.1 - Official agencies.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... half), OH, PA, WV (northern panhandle). Federal Reserve Bank of Richmond, P.O. Box 27622, Richmond, VA 23261 Richmond, Atlanta AL, DC, FL, LA (southern half), MD, MS (southern half), NC, SC, TN (eastern...

  14. 31 CFR 315.1 - Official agencies.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... half), OH, PA, WV (northern panhandle). Federal Reserve Bank of Richmond, P.O. Box 27622, Richmond, VA 23261 Richmond, Atlanta AL, DC, FL, LA (southern half), MD, MS (southern half), NC, SC, TN (eastern...

  15. 31 CFR 353.1 - Official agencies.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... half), OH, PA, WV (northern panhandle). Federal Reserve Bank of Richmond, P.O. Box 27622, Richmond, VA 23261 Richmond, Atlanta AL, DC, FL, LA (southern half), MD, MS (southern half), NC, SC, TN (eastern...

  16. 31 CFR 353.1 - Official agencies.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... half), OH, PA, WV (northern panhandle). Federal Reserve Bank of Richmond, P.O. Box 27622, Richmond, VA 23261 Richmond, Atlanta AL, DC, FL, LA (southern half), MD, MS (southern half), NC, SC, TN (eastern...

  17. 31 CFR 315.1 - Official agencies.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (eastern half), NJ (southern half), OH, PA, WV (northern panhandle). Federal Reserve Bank of Richmond, P.O. Box 27622, Richmond, VA 23261 Richmond, Atlanta AL, DC, FL, LA (southern half), MD, MS (southern...

  18. 31 CFR 330.9 - Fiscal agents.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... half), OH, PA, WV (northern panhandle). Federal Reserve Bank of Richmond, P.O. Box 27622, Richmond, VA 23261 Richmond, Atlanta AL, DC, FL, LA (southern half), MD, MS (southern half), NC, SC, TN (eastern...

  19. 31 CFR 352.13 - Fiscal agents.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., PA, WV (northern panhandle). Federal Reserve Bank of Richmond, P.O. Box 27622, Richmond, VA 23261 Richmond, Atlanta AL, DC, FL, LA (southern half), MD, MS (southern half), NC, SC, TN (eastern half), VA,...

  20. 31 CFR 352.13 - Fiscal agents.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., PA, WV (northern panhandle). Federal Reserve Bank of Richmond, P.O. Box 27622, Richmond, VA 23261 Richmond, Atlanta AL, DC, FL, LA (southern half), MD, MS (southern half), NC, SC, TN (eastern half), VA,...

  1. 31 CFR 352.13 - Fiscal agents.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... half), OH, PA, WV (northern panhandle). Federal Reserve Bank of Richmond, P.O. Box 27622, Richmond, VA 23261 Richmond, Atlanta AL, DC, FL, LA (southern half), MD, MS (southern half), NC, SC, TN (eastern...

  2. 31 CFR 353.1 - Official agencies.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... half), OH, PA, WV (northern panhandle). Federal Reserve Bank of Richmond, P.O. Box 27622, Richmond, VA 23261 Richmond, Atlanta AL, DC, FL, LA (southern half), MD, MS (southern half), NC, SC, TN (eastern...

  3. 31 CFR 315.1 - Official agencies.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... half), OH, PA, WV (northern panhandle). Federal Reserve Bank of Richmond, P.O. Box 27622, Richmond, VA 23261 Richmond, Atlanta AL, DC, FL, LA (southern half), MD, MS (southern half), NC, SC, TN (eastern...

  4. 1. LOOKING SOUTHWEST TOWARD NORTH AND WEST SIDES OF OFFICE; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. LOOKING SOUTHWEST TOWARD NORTH AND WEST SIDES OF OFFICE; LABORATORY AND ELECTRICITY SUPPLY HOUSE TO THE RIGHT. - Standard Lime & Stone Quarry, Office, County Route 27, Millville, Jefferson County, WV

  5. 1. NORTHWEST FRONT, SOUTHWEST SIDE (SPRING HOUSE IN FOREGROUND; BATH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. NORTHWEST FRONT, SOUTHWEST SIDE (SPRING HOUSE IN FOREGROUND; BATH HOUSE AT REAR) (4 x 5 negative; 5 x 7 print) - Salt Sulphur Springs, Spring House, U.S. Route 219, Salt Sulphur Springs, Monroe County, WV

  6. 2. SHOWING (LEFT TO RIGHT) CHAPEL, STORE BUILDING, SPRING HOUSE, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. SHOWING (LEFT TO RIGHT) CHAPEL, STORE BUILDING, SPRING HOUSE, AND BATH HOUSE, SOUTHEAST FACADES (4 x 5 negative; 5 x 7 print) - Salt Sulpher Springs, U.S. Route 219, Salt Sulphur Springs, Monroe County, WV

  7. 76 FR 68378 - Approval and Promulgation of Air Quality Implementation Plans; District of Columbia, Maryland...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-04

    ..., Maryland, Virginia, and West Virginia; Determinations of Attainment of the 1997 Fine Particle Standard for... Virginia-Maryland (WV-MD) fine particle (PM 2.5 ) nonattainment areas (hereafter referred to as ``Areas...

  8. 25. William E. Barrett, Photographer, August 1975. INTERIOR OF SAWMILL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    25. William E. Barrett, Photographer, August 1975. INTERIOR OF SAWMILL LOOKING WEST. ROLLERS FROM TRIPLE EDGER (LEFT) AND DOUBLE EDGER (RIGHT) AND HEAVY TIMBER ROLLERS FROM CENTER MILL (CENTER). - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  9. 35. INTERIOR VIEW, WHEELBRATORFRYE SHOT PEENER FOR REMOVAL OF RUST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    35. INTERIOR VIEW, WHEELBRATOR-FRYE SHOT PEENER FOR REMOVAL OF RUST AND SCALE; NOTE TOOLS ARE TUMBLED WITH BLASTED WITH LEAD SHOT TO CLEAN SURFACES - Warwood Tool Company, Foot of Nineteenth Street, Wheeling, Ohio County, WV

  10. 27 CFR 9.111 - Kanawha River Valley.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...., dated 1968, photorevised 1975; (4) Glenwood, W. Va.—Ohio, dated 1968; (5) Milton, W. Va., dated 1972; (6... in Cabell County, WV. (Milton quadrangle) (4) The boundary proceeds in a straight line...

  11. 53. Photocopy of photograph, c. 1946. GENERAL INTERIOR VIEW OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    53. Photocopy of photograph, c. 1946. GENERAL INTERIOR VIEW OF GENERATOR ROOM. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files, Dam No. 5 listing) - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  12. 61. Photocopy of photograph, c. 1949. DETAIL OF SWITCHBOARD WITH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    61. Photocopy of photograph, c. 1949. DETAIL OF SWITCHBOARD WITH MODIFICATIONS. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files, Dam No. 5 listing) - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  13. 60. Photocopy of photograph, no date. DETAIL OF SWITCHBOARD. (Courtesy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    60. Photocopy of photograph, no date. DETAIL OF SWITCHBOARD. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files, Properties-Buildings and Equipment listing) - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  14. Detail exterior view looking northwest showing field gas cleaner in ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail exterior view looking northwest showing field gas cleaner in the center. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  15. View of steam powered air compressor in boiler house. Gas ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of steam powered air compressor in boiler house. Gas engine powered electric generators are visible in far left background. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  16. DETAIL VIEW OF STEAM CHEST FOR LOW PRESSURE STAGE ENGINE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL VIEW OF STEAM CHEST FOR LOW PRESSURE STAGE ENGINE OF UNIT #3. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  17. Detail view of valve mechanisms and goverenor on high pressure ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of valve mechanisms and goverenor on high pressure stage engine of unit 43. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  18. DETAIL VIEW OF OIL CONTAINER DESIGNED AS PART OF LUBRICATING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL VIEW OF OIL CONTAINER DESIGNED AS PART OF LUBRICATING SYSTEM FOR UNIT #3. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  19. Detail view of gauges that record pressure of gas coming ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of gauges that record pressure of gas coming into the engine house. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  20. Exterior view looking north/northwest showing water intake from Little Kanawha ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Exterior view looking north/northwest showing water intake from Little Kanawha River on right. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  1. Detail view of feedwater pump (below) and preheater tanks (above) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of feedwater pump (below) and preheater tanks (above) in boiler house. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  2. Detail exterior view looking southwest of gas cooling system. Engine ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail exterior view looking southwest of gas cooling system. Engine house is shown in right background. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  3. Detail view of lubricating oil pumps used in maintenance of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of lubricating oil pumps used in maintenance of the engines and compressors. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  4. Detail view of condensor located below the floor level of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of condensor located below the floor level of the pumphouse. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  5. General exterior view looking north. Boiler house is center/left. Engine ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General exterior view looking north. Boiler house is center/left. Engine house is center right. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  6. Interior view of boiler house looking south. Boiler units are ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior view of boiler house looking south. Boiler units are on left. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  7. Detail view of steam chest for low pressure stage engine ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of steam chest for low pressure stage engine of unit 43. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  8. Detail view of oil container designed as part of lubricating ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of oil container designed as part of lubricating system for unit 43. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  9. Exterior view looking northwest with construction facilities of "new" pumping ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Exterior view looking northwest with construction facilities of "new" pumping station in foreground. Doug Hine is man in picture. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  10. General interior view of pumphouse looking southwest. Compressor unit 40 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General interior view of pumphouse looking southwest. Compressor unit 40 is in foreground. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  11. Detail exterior view looking north showing piping system adjacent to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail exterior view looking north showing piping system adjacent to engine house. Gas cooling system is on far right. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  12. Detail view of steam chest and valve mechanisms for high ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of steam chest and valve mechanisms for high pressure stage of unit 40. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  13. Detail view of steam chest for low pressure stage of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of steam chest for low pressure stage of unit 40. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  14. Exterior view of boiler house looking southwest with steam exhaust ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Exterior view of boiler house looking southwest with steam exhaust vents in foreground. Engine house is on left. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  15. General view looking north showing boilers with units 47 and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view looking north showing boilers with units 47 and 48 in right foreground. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  16. Detail view of wrenches used in maintenance of engines and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of wrenches used in maintenance of engines and compressors. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  17. Detail view of gauges that record pressure of gas leaving ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of gauges that record pressure of gas leaving the engine house. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  18. DETAIL VIEW OF UNIT #3 WITH HIGH PRESSURE STAGE COMPRESSOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL VIEW OF UNIT #3 WITH HIGH PRESSURE STAGE COMPRESSOR IN LEFT FOREGROUND. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  19. Detail view of unit 43 with high pressure stage compressor ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of unit 43 with high pressure stage compressor in left foreground. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  20. 7. VIEW WEST, FERNOW EXPERIMENTAL FOREST WELL HOUSE, FERNOW EXPERIMENTAL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. VIEW WEST, FERNOW EXPERIMENTAL FOREST WELL HOUSE, FERNOW EXPERIMENTAL FOREST BUNKHOUSE, FERNOW EXPERIMENTAL FOREST GARAGE, AND FERNOW EXPERIMENTAL FOREST RESIDENCE. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  1. 19. LOOKING NORTH ALONG ROAD BISECTING SITE; PEBBLE LIME SILO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. LOOKING NORTH ALONG ROAD BISECTING SITE; PEBBLE LIME SILO ON THE RIGHT, MAIN SUPPLY BUILDING AND MACHINE SHOP ON THE LEFT. - Standard Lime & Stone Quarry, County Route 27, Millville, Jefferson County, WV

  2. Environmental perspective facing south showing chicken house, tractor shed, and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Environmental perspective facing south showing chicken house, tractor shed, and homestead - Norris Farm, .5 mile west of County Road 857 & .25 mile east of County Road 88/1, Cheat Neck, Monongalia County, WV

  3. 8. Environmental view facing northwest showing pond in relationship to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Environmental view facing northwest showing pond in relationship to house - John Bly House, East side of County Road 857, just north of intersection with Quarry Run Road, Cheat Neck, Monongalia County, WV

  4. 14. INTERIOR VIEW, DETAIL OF TRIMMED FLASH; FLASH IS EXCESS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. INTERIOR VIEW, DETAIL OF TRIMMED FLASH; FLASH IS EXCESS METAL EXTRUDED BETWEEN THE DIES USED TO FORGE THE BLADE END OF THE POST HOLE DIGGER - Warwood Tool Company, Foot of Nineteenth Street, Wheeling, Ohio County, WV

  5. 2. GENERAL VIEW SHOWING SIMPSON CREEK BRIDGE WITH BRIDGEPORT LAMP ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. GENERAL VIEW SHOWING SIMPSON CREEK BRIDGE WITH BRIDGEPORT LAMP AND CHIMNEY COMPANY IN BACKGROUND. - Bridgeport Lamp Chimney Company, Simpson Creek Bridge, Spanning Simpson Creek, State Route 58 vicinity, Bridgeport, Harrison County, WV

  6. 4. MAIN STREET IN RICHARD, SHOWING FORMER COMPANY HOUSING ON ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. MAIN STREET IN RICHARD, SHOWING FORMER COMPANY HOUSING ON EITHER SIDE William E. Barrett, photographer, 1976 - Elkins Coal & Coke Company, Richard Ovens, Deckers Creek, State Route 7-92, Dellslow, Monongalia County, WV

  7. The Public Use Limitation in Eminent Domain: "Handley v. Cook."

    ERIC Educational Resources Information Center

    Grill, Donna P.

    1979-01-01

    It is time for the courts to rigorously scrutinize allegations of public use in order to protect the property rights of private individuals. Available from West Virginia Law Review, W.V.U. Law Center, Morgantown, WV 26506. (Author)

  8. 6. INTERIOR VIEW, HIGH CARBON HOT ROLLED SHEET STEEL FOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. INTERIOR VIEW, HIGH CARBON HOT ROLLED SHEET STEEL FOR NAIL PLATE BEING LOADED ON THE CRADLE USED DURING THE PICKLING PROCESS - LaBelle Iron Works, Thirtieth & Wood Streets, Wheeling, Ohio County, WV

  9. 5. INTERIOR VIEW, HIGH CARBON HOT ROLLED SHEET STEEL FOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. INTERIOR VIEW, HIGH CARBON HOT ROLLED SHEET STEEL FOR NAIL PLATE BEING REMOVED FROM THE CRADLE USED DURING THE PICKLING PROCESS - LaBelle Iron Works, Thirtieth & Wood Streets, Wheeling, Ohio County, WV

  10. 12. Credit WS. Basement of Mill, showing wooden flywheels to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Credit WS. Basement of Mill, showing wooden flywheels to water wheel and Fairbanks. Morse 20 hp, 350 rpm diesel engine, patented April 20, 1920. - Bunker Hill Mill, County Route 26, Bunker Hill, Berkeley County, WV

  11. 14. INTERIOR VIEW OF FIREPLACE AND SURROUNDING WALL IN FIRST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. INTERIOR VIEW OF FIREPLACE AND SURROUNDING WALL IN FIRST FLOOR, NORTHWEST PARLOR, NORTH WALL, WITH SCALE (NOTE WALL STENCILING) - George W. Eckhart House, 810 Main Street, Wheeling, Ohio County, WV

  12. 38. INTERIOR VIEW, DENISON MULTIPRESS FOR INSERTION OF WEDGES ONTO ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    38. INTERIOR VIEW, DENISON MULTI-PRESS FOR INSERTION OF WEDGES ONTO HANDLES AND CUTTING OFF SCRAP END OF HANDLE FOLLOWING WEDGE INSERTION, BRIAN KIMBLE, OPERATOR - Warwood Tool Company, Foot of Nineteenth Street, Wheeling, Ohio County, WV

  13. 16. William E. Barrett, Photographer, August 1975. CENTER MILL (RIGHTHANDED) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. William E. Barrett, Photographer, August 1975. CENTER MILL (RIGHT-HANDED) WITH CARRIAGE TRACKS AND BANDSAW HOUSING INTACT. LOG CLAMPS ON THIS CARRIAGE WERE PNEUMATICALLY OPERATED. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  14. 21. William E. Barrett, Photographer, August 1975. EDGER SAWS FOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. William E. Barrett, Photographer, August 1975. EDGER SAWS FOR RIPPING BOARD TO VARIOUS WIDTHS. BLADES VISIBLE BEHIND ROLLERS. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  15. 8. William E. Barrett, Photographer, August 1975. LOG DOCK AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. William E. Barrett, Photographer, August 1975. LOG DOCK AND PARTIALLY DEMOLISHED JACKSLIP USED FOR HAULING LOGS UP TO SAWMILL. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  16. 13. William E. Barrett, Photographer, August 1975. INTERIOR OF SAWMILL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. William E. Barrett, Photographer, August 1975. INTERIOR OF SAWMILL LOOKING EAST. LOGS FOR CENTER MILL ROLLED RIGHT TO CONVEYOR WHICH CARRIED THEM TO SECOND SLOPING DECK. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  17. 11. William E. Barrett, Photographer, August 1975. INTERIOR OF SAWMILL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. William E. Barrett, Photographer, August 1975. INTERIOR OF SAWMILL SHOWING STEAM CYLINDER AND PISTON ROD OF LEFT-HAND MILL (LEFT) AND HOUSING OF CENTER BANDSAW. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  18. 20. William E. Barrett, Photographer, August 1975. INTERIOR OF SAWMILL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. William E. Barrett, Photographer, August 1975. INTERIOR OF SAWMILL LOOKING EAST. EDGER SAW AT LOWER LEFT, TRIMMERS AT RIGHT. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  19. 19. William E. Barrett, Photographer, August 1975. LOWER BAND SAW ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. William E. Barrett, Photographer, August 1975. LOWER BAND SAW PULLEYS OF RIGHT-HAND MILL. DRIVE PULLEY IN BELOW TENSION PULLEY. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  20. 6. William E. Barrett, Photographer, 1975. GENERAL VIEW LOOKING EAST. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. William E. Barrett, Photographer, 1975. GENERAL VIEW LOOKING EAST. SAWMILL ON RIGHT. SECONDARY WOODWORKING SHOPS ON LEFT PARTIALLY DEMOLISHED. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  1. 3. Photocopy of 1977 photograph (original negative lost) 2307 (AT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Photocopy of 1977 photograph (original negative lost) 2307 (AT EXTREME RIGHT) THROUGH 2319 CHAPLINE STREET - Chapline Street Row Historic District, 2301-2319 Chapline Street, Wheeling, Ohio County, WV

  2. 9. LOOKING EAST AND TOWARD SMALL TANK, 60FOOT SQUARE BASIN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. LOOKING EAST AND TOWARD SMALL TANK, 60-FOOT SQUARE BASIN (ON EXTREME RIGHT) AND 125-FOOT BASIN (IN BACKGROUND). - Standard Lime & Stone Quarry, Tanks & Settling Basins, County Route 27, Millville, Jefferson County, WV

  3. 22. William E. Barrett, Photographer, August 1975. CHIPPER OR 'HOG' ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. William E. Barrett, Photographer, August 1975. CHIPPER OR 'HOG' FOR REDUCING SCRAPS TO WOOD CHIPS. HOUSING PARTIALLY REMOVED. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  4. 13. View South, showing the remaining pier footings for the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. View South, showing the remaining pier footings for the steam engine water tower for the Chesapeake and Ohio Railroad. - Cotton Hill Station Bridge, Spanning New River at State Route 16, Cotton Hill, Fayette County, WV

  5. Martinsburg Plant Upgrade Helps Waters Near and Far

    EPA Pesticide Factsheets

    With key financial assistance from EPA, the City of Martinsburg, W.V., has revamped its wastewater treatment plant to achieve steep pollution reductions that will benefit local creeks and the Chesapeake Bay.

  6. 1. LOOKING NORTH, SHOWING IODINE SPRING (FOREGROUND), SALT SULPHUR SPRING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. LOOKING NORTH, SHOWING IODINE SPRING (FOREGROUND), SALT SULPHUR SPRING (LEFT BACKGROUND), AND TWIN COTTAGES (UPPER RIGHT) (4 x 5 negative; 5 x 7 print) - Salt Sulpher Springs, U.S. Route 219, Salt Sulphur Springs, Monroe County, WV

  7. 44. William E. Barrett, Photographer, August 1975. GENERAL VIEW OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    44. William E. Barrett, Photographer, August 1975. GENERAL VIEW OF MAIN DRIVE ENGINE FOR SAWMILL; A FILER AND STOWELL, TYPE '1900', HEAVY DUTY CORLISS ENGINE (set. no. 4352). - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  8. 75 FR 71459 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-23

    ... Products, Leased Workers from Staff Mark & SC Voc. Rehab. 74,575 International Business Charleston, WV......... October 27, 2009. Systems, Inc., Some Wages Reported Under Motorvac Technologies, Inc. 74,815 Areva...

  9. 10. INTERIOR VIEW OF EYE PRESS AREA, SAME AS ABOVE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. INTERIOR VIEW OF EYE PRESS AREA, SAME AS ABOVE WITH MEN AT WORK: CRAIG TSCHAPPAT, HEATER; JEFF MILLER, OPERATOR; JOHN TOTH, SAWMAN - Warwood Tool Company, Foot of Nineteenth Street, Wheeling, Ohio County, WV

  10. 30 CFR 35.3 - Consultation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... MINING PRODUCTS FIRE-RESISTANT HYDRAULIC FLUIDS General Provisions § 35.3 Consultation. By appointment... Administration, Approval and Certification Center, 765 Technology Drive, Triadelphia, WV 26059, to discuss with...

  11. 30 CFR 35.3 - Consultation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... MINING PRODUCTS FIRE-RESISTANT HYDRAULIC FLUIDS General Provisions § 35.3 Consultation. By appointment... Administration, Approval and Certification Center, 765 Technology Drive, Triadelphia, WV 26059, to discuss with...

  12. 30 CFR 35.3 - Consultation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... MINING PRODUCTS FIRE-RESISTANT HYDRAULIC FLUIDS General Provisions § 35.3 Consultation. By appointment... Administration, Approval and Certification Center, 765 Technology Drive, Triadelphia, WV 26059, to discuss with...

  13. 30 CFR 35.3 - Consultation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... MINING PRODUCTS FIRE-RESISTANT HYDRAULIC FLUIDS General Provisions § 35.3 Consultation. By appointment... Administration, Approval and Certification Center, 765 Technology Drive, Triadelphia, WV 26059, to discuss with...

  14. 30 CFR 35.3 - Consultation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... MINING PRODUCTS FIRE-RESISTANT HYDRAULIC FLUIDS General Provisions § 35.3 Consultation. By appointment... Administration, Approval and Certification Center, 765 Technology Drive, Triadelphia, WV 26059, to discuss with...

  15. 42 CFR 37.2 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Safety and Health, Box 4258, Morgantown, WV 26505. Although the Division of Respiratory Disease Studies... and NIOSH mean the National Institute for Occupational Safety and Health Center for Disease Control...

  16. 42 CFR 37.2 - Definitions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... within the Centers for Disease Control and Prevention (CDC). Within NIOSH, the Division of Respiratory Disease Studies (DRDS), Box 4258, Morgantown, WV 26504, formerly called the Appalachian Laboratory for...

  17. 42 CFR 37.2 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Safety and Health, Box 4258, Morgantown, WV 26505. Although the Division of Respiratory Disease Studies... and NIOSH mean the National Institute for Occupational Safety and Health Center for Disease Control...

  18. 3. Photocopied August 1975 from The Evolution of Modern Band ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Photocopied August 1975 from The Evolution of Modern Band Saw Mills for Sawing Logs, Dewitt Clinton Prescott, 1910. VIEW OF BAND SAW. *NOTE* 4'x 5' NEGATIVE - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  19. 4. Photocopied August 1975 from The Evolution of Modern Band ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Photocopied August 1975 from The Evolution of Modern Band Saw Mills for Sawing Logs, Dewitt Clinton Prescott, 1910. THREE-BLOCK LOG CARRIAGE. *NOTE* 4'x 5' NEGATIVE - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  20. Homelessness Assistance and Resources

    MedlinePlus

    ... VI UT VT VA WA WV WI WY Disaster Recovery Homelessness Toolkit Recovery Guide for Local Jurisdictions ... Jurisdictions is now available as part of the Disaster Recovery Homelessness Toolkit . This toolkit is for communities ...

  1. 2. DETAIL OF INVERTED MINE CARS, LOOKING SOUTHWEST; NOTE SHORT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. DETAIL OF INVERTED MINE CARS, LOOKING SOUTHWEST; NOTE SHORT WHEEL BASE NEEDED FOR DUMPING CONTENTS - Nuttallburg Mine Complex, Main Mine, North side of New River, 2.7 miles upstream from Fayette Landing, Lookout, Fayette County, WV

  2. 9. TRANSMISSION GEARING FROM SPUR WHEEL (right) USED TO INCREASE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. TRANSMISSION GEARING FROM SPUR WHEEL (right) USED TO INCREASE REVOLUTIONS PER MINUTE William E. Barrett, photographer, 1973 - Thomas Shepherd's Grist Mill, High Street Vicinity, Shepherdstown, Jefferson County, WV

  3. 63. Photocopy of photograph, no date. MAP OF POTOMAC EDISON ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    63. Photocopy of photograph, no date. MAP OF POTOMAC EDISON COMPANY SYSTEM. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  4. 36. POT IN OVEN NO. 9. MEASURING STICK IS USED ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    36. POT IN OVEN NO. 9. MEASURING STICK IS USED TO MAKE SURE THAT POT IS ALL THE WAY IN. - Seneca Glass Company Factory, Beechurst Avenue between Sixth & Eighth Streets, Morgantown, Monongalia County, WV

  5. 45. INTERIOR VIEW SHOWING CONVEYOR BELT SYSTEM WHICH CONVEY THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    45. INTERIOR VIEW SHOWING CONVEYOR BELT SYSTEM WHICH CONVEY THE HARDENED NAILS TO THE DRAWBACK TUBE FOR TEMPERING; MOTIONED STOPPED - LaBelle Iron Works, Thirtieth & Wood Streets, Wheeling, Ohio County, WV

  6. 47. INTERIOR VIEW, DETAIL OF CONVEYOR BELT SYSTEM SYSTEM WITH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    47. INTERIOR VIEW, DETAIL OF CONVEYOR BELT SYSTEM SYSTEM WITH BACK BELT DROPPING HARDENED NAILS ON THE FRONT BELT TO BE TEMPERED; MOTION STOPPED - LaBelle Iron Works, Thirtieth & Wood Streets, Wheeling, Ohio County, WV

  7. 42. INTERIOR VIEW OF THE NAIL HARDENER USED TO HARDEN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    42. INTERIOR VIEW OF THE NAIL HARDENER USED TO HARDEN AND TEMPER THE NAILS; WEST TUBES IN FOREGRPUND AND DRAWBACK TUBE IN THE CENTER - LaBelle Iron Works, Thirtieth & Wood Streets, Wheeling, Ohio County, WV

  8. 30. Credit JTL. Second floor, view of Eureka Milling Separator, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    30. Credit JTL. Second floor, view of Eureka Milling Separator, by S. Howes Co., (Silver Creek, NY); separated out undersired grains and impurities prior to milling. - Bunker Hill Mill, County Route 26, Bunker Hill, Berkeley County, WV

  9. 21. Credit WS. Ground floor, Midget Marvel milling machine, a ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. Credit WS. Ground floor, Midget Marvel milling machine, a 25 barrel day machine by the Anglo American Mill Co. (Owensboro, KY), without covers, exposing rollers and sifters. - Bunker Hill Mill, County Route 26, Bunker Hill, Berkeley County, WV

  10. 27. Credit JTL. Second floor, detail of Eureka horizontal wheat ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    27. Credit JTL. Second floor, detail of Eureka horizontal wheat scourer, by S. Howes Co., (Silver Creek, NY). After leaving scourer, grain passed directly to the Midget Marvel Machine. - Bunker Hill Mill, County Route 26, Bunker Hill, Berkeley County, WV

  11. 75 FR 52977 - Agency Information Collection Activities: Proposed Collection; Comments Requested

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-30

    ... of Alcohol, Tobacco, Firearms and Explosives Agency Information Collection Activities: Proposed... Alcohol, Tobacco, Firearms and Explosives (ATF), will be submitting the following information collection... Desiree Winger, Firearms and Explosives Imports Branch, 244 Needy Road, Martinsburg, WV 25405. Written...

  12. 77 FR 4827 - Agency Information Collection Activities; Proposed Collection; Comments Requested: FFL Out-of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-31

    ... of Alcohol, Tobacco, Firearms and Explosives Agency Information Collection Activities; Proposed... Collection. The Department of Justice (DOJ), Bureau of Alcohol, Tobacco, Firearms and Explosives (ATF), will...-4647, Acting Chief, Federal Firearms Licensing Center, 244 Needy Road, Martinsburg, WV 25405. Written...

  13. 75 FR 52978 - Agency Information Collection Activities: Proposed Collection; Comments Requested

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-30

    ... of Alcohol, Tobacco, Firearms and Explosives Agency Information Collection Activities: Proposed... Federal firearms license. The Department of Justice (DOJ), Bureau of Alcohol, Tobacco, Firearms and... Firearms Licensing Center, 244 Needy Road, Martinsburg, WV 20226. Written comments and suggestions from...

  14. View west, barn, east elevation Woods Homestead, Barn, County ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View west, barn, east elevation - Woods Homestead, Barn, County Route 12 on north side of North Fork of Hughes River, 2.2 miles north & east of Goose Run Road intersection, Harrisville, Ritchie County, WV

  15. View south, barn, north elevation Woods Homestead, Barn, County ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View south, barn, north elevation - Woods Homestead, Barn, County Route 12 on north side of North Fork of Hughes River, 2.2 miles north & east of Goose Run Road intersection, Harrisville, Ritchie County, WV

  16. View west, interior, detail of joinery Woods Homestead, Barn, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View west, interior, detail of joinery - Woods Homestead, Barn, County Route 12 on north side of North Fork of Hughes River, 2.2 miles north & east of Goose Run Road intersection, Harrisville, Ritchie County, WV

  17. View southeast, general view, barn at left Woods Homestead, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View southeast, general view, barn at left - Woods Homestead, County Route 12 on north side of North Fork of Hughes River, 2.2 miles north & east of Goose Run Road intersection, Harrisville, Ritchie County, WV

  18. View north, barn, south elevation Woods Homestead, Barn, County ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View north, barn, south elevation - Woods Homestead, Barn, County Route 12 on north side of North Fork of Hughes River, 2.2 miles north & east of Goose Run Road intersection, Harrisville, Ritchie County, WV

  19. View east, barn, west elevation Woods Homestead, Barn, County ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View east, barn, west elevation - Woods Homestead, Barn, County Route 12 on north side of North Fork of Hughes River, 2.2 miles north & east of Goose Run Road intersection, Harrisville, Ritchie County, WV

  20. Preparation and characterization of malonic acid cross-linked chitosan and collagen 3D scaffolds: an approach on non-covalent interactions.

    PubMed

    Mitra, Tapas; Sailakshmi, G; Gnanamani, A; Mandal, A B

    2012-05-01

    The present study emphasizes the influence of non-covalent interactions on the mechanical and thermal properties of the scaffolds of chitosan/collagen origin. Malonic acid (MA), a bifuncitonal diacid was chosen to offer non-covalent cross-linking. Three dimensional scaffolds was prepared using chitosan at 1.0% (w/v) and MA at 0.2% (w/v), similarly collagen 0.5% (w/v) and MA 0.2% (w/v) and characterized. Results on FT-IR, TGA, DSC, SEM and mechanical properties (tensile strength, stiffness, Young's modulus, etc.) assessment demonstrated the existence of non-covalent interaction between MA and chitosan/collagen, which offered flexibility and high strength to the scaffolds suitable for tissue engineering research. Studies using NIH 3T3 fibroblast cells suggested biocompatibility nature of the scaffolds. Docking simulation study further supports the intermolecular hydrogen bonding interactions between MA and chitosan/collagen.

  1. 6. VIEW EAST OF CEMENT PIER AND TRAFFIC DECK SUPPORT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. VIEW EAST OF CEMENT PIER AND TRAFFIC DECK SUPPORT SYSTEM; NOTE FLOOR BEAMS AND STRINGERS VIEWED FROM UNDERNEATH THE BRIDGE - Water Street Bridge, County Route 119/26, over Guyandotte River, Logan, Logan County, WV

  2. 5. DETAIL OF THE INSIDE ROBERTS AND SCHAEFER LOADING BOOM, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. DETAIL OF THE INSIDE ROBERTS AND SCHAEFER LOADING BOOM, WITH COUNTERWEIGHT (RIGHT), NOTE METAL CONVEYOR BELT (FOREGROUND) - Nuttallburg Mine Complex, Tipple, North side of New River, 2.7 miles upstream from Fayette Landing, Lookout, Fayette County, WV

  3. 8. VIEW EAST, CIVILIAN CONSERVATION CORPS CAMP PARSONS GARAGE, MODERN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. VIEW EAST, CIVILIAN CONSERVATION CORPS CAMP PARSONS GARAGE, MODERN SHED, CIVILIAN CONSERVATION CORPS CAMP PARSONS BLACKSMITH SHOP, AND MODERN SHED. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  4. 4. EASTBOUND VIEW. NORTH TRACK WAITING STATION ON LEFT. STATION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. EASTBOUND VIEW. NORTH TRACK WAITING STATION ON LEFT. STATION ON RIGHT. NOTE TUNNEL IN BACKGROUND. - Baltimore & Ohio Railroad, Harpers Ferry Station, Potomac Street, Harpers Ferry, Jefferson County, WV

  5. View of Harpers Ferry, station behind trees in lower right. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of Harpers Ferry, station behind trees in lower right. Taken from Maryland Heights Ridge from the east. - Baltimore & Ohio Railroad, Harpers Ferry Station, Potomac Street, Harpers Ferry, Jefferson County, WV

  6. View of Harpers Ferry, station to right at end of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of Harpers Ferry, station to right at end of CSX Railroad Bridge. Taken from Maryland Heights Ridge from the east. - Baltimore & Ohio Railroad, Harpers Ferry Station, Potomac Street, Harpers Ferry, Jefferson County, WV

  7. 7. William E. Barrett, Photographer, 1974. SKEWED VIEW SHOWING CHEAT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. William E. Barrett, Photographer, 1974. SKEWED VIEW SHOWING CHEAT RIVER VALLEY, REMAINS OF 1887 PIER AND c. 1900 MASONRY ARCHES. - Baltimore & Ohio Railroad, Tray Run Viaduct, Spanning Tray Run, Rowlesburg, Preston County, WV

  8. North and east elevations of tractor shed facing southwest ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    North and east elevations of tractor shed facing southwest - Norris Farm, Tractor Shed-Combine Barn, .5 mile west of County Road 857 & .25 mile east of County Road 88/1, Cheat Neck, Monongalia County, WV

  9. South and west elevations of tractor shed facing northeast ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    South and west elevations of tractor shed facing northeast - Norris Farm, Tractor Shed-Combine Barn, .5 mile west of County Road 857 & .25 mile east of County Road 88/1, Cheat Neck, Monongalia County, WV

  10. 27 CFR 9.111 - Kanawha River Valley.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...., dated 1958; (12) Sissonville, W. Va., dated 1958; (13) Romance, W. Va.,—Ky., dated 1957; (14) Kentuck, W... Johns Branch and Sugar Creek in the town of Romance, in Jackson County, WV. (Romance quadrangle) (8)...

  11. 27 CFR 9.111 - Kanawha River Valley.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...., dated 1958; (12) Sissonville, W. Va., dated 1958; (13) Romance, W. Va.,—Ky., dated 1957; (14) Kentuck, W... Johns Branch and Sugar Creek in the town of Romance, in Jackson County, WV. (Romance quadrangle) (8)...

  12. 27 CFR 9.111 - Kanawha River Valley.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...., dated 1958; (12) Sissonville, W. Va., dated 1958; (13) Romance, W. Va.,—Ky., dated 1957; (14) Kentuck, W... Johns Branch and Sugar Creek in the town of Romance, in Jackson County, WV. (Romance quadrangle) (8)...

  13. 27 CFR 9.111 - Kanawha River Valley.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...., dated 1958; (12) Sissonville, W. Va., dated 1958; (13) Romance, W. Va.,—Ky., dated 1957; (14) Kentuck, W... Johns Branch and Sugar Creek in the town of Romance, in Jackson County, WV. (Romance quadrangle) (8)...

  14. Anchor Casting and Portal Strut at West Bank Abutment, Endpost ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Anchor Casting and Portal Strut at West Bank Abutment, Endpost Base and Granite Plinth - Baltimore & Ohio Railroad, Bollman Bridge, Spanning Potomac River at Harpers Ferry, Harpers Ferry, Jefferson County, WV

  15. 2. Photocopy of advertisement (from the collection of Dr. Margaret ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Photocopy of advertisement (from the collection of Dr. Margaret Ballard, Union, West Virginia) late 19th century AERIAL VIEW OF TOWN - Red Sulphur Springs, Route 12, Salt Sulphur Springs, Monroe County, WV

  16. 34. View of pier 3, showing supporting main anchor arm ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    34. View of pier 3, showing supporting main anchor arm and cantilever arm spans, as seen from shore near pier 4, looking north - Williamstown-Marietta Bridge, Spanning Ohio River between Williamstown & Marietta, Williamstown, Wood County, WV

  17. 22. View showing main anchor arm, as viewed from main ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. View showing main anchor arm, as viewed from main cantilever arm looking south. Note upper chord eyebar arrangement. - Williamstown-Marietta Bridge, Spanning Ohio River between Williamstown & Marietta, Williamstown, Wood County, WV

  18. 6. VIEW OF POWER PLANT BUILDING LOOKING NORTHWEST. DRY CANAL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. VIEW OF POWER PLANT BUILDING LOOKING NORTHWEST. DRY CANAL BED TO THE LEFT. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  19. 1. VIEW OF POWER PLANT LOOKING SOUTHEAST. SEVEN TURBINE FLUMES ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. VIEW OF POWER PLANT LOOKING SOUTHEAST. SEVEN TURBINE FLUMES VISIBLE IN FRONT OF BUILDING. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  20. 10. WEST WALL OF POWER PLANT BUILDING LOOKING EAST SOUTHEAST. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. WEST WALL OF POWER PLANT BUILDING LOOKING EAST SOUTHEAST. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  1. 3. VIEW OF POWER PLANT LOOKING SOUTH INTO THE REMAINS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. VIEW OF POWER PLANT LOOKING SOUTH INTO THE REMAINS OF THE TURBINE FLUMES. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  2. 9. EXTERIOR PERSPECTIVE OF POWER PLANT BUILDING LOOKING NORTHEAST. DRY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. EXTERIOR PERSPECTIVE OF POWER PLANT BUILDING LOOKING NORTHEAST. DRY CANAL BED IN FOREGROUND. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  3. 8. VIEW OF WESTERN END OF THE POWER PLANT BUILDING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. VIEW OF WESTERN END OF THE POWER PLANT BUILDING LOOKING NORTH. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  4. 12. CANAL SLUICE GATE LOCATED 150' WEST OF POWER PLANT. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. CANAL SLUICE GATE LOCATED 150' WEST OF POWER PLANT. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  5. 11. EAST WALL OF POWER PLANT BUILDING LOOKING WEST. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. EAST WALL OF POWER PLANT BUILDING LOOKING WEST. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  6. 18. TURBINE AND GENERATOR SHAFT IN CONCRETE HOUSING OF THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. TURBINE AND GENERATOR SHAFT IN CONCRETE HOUSING OF THE TURBINE FLUME. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  7. 13. VIEW FROM POTOMAC RIVER BRIDGE PLATFORM WEST TOWARDS STATION. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. VIEW FROM POTOMAC RIVER BRIDGE PLATFORM WEST TOWARDS STATION. HARPERS FERRY DEPOT IS ON LEFT, NORTH TRACK WAITING STATION IS ON RIGHT. - Baltimore & Ohio Railroad, Harpers Ferry Station, Potomac Street, Harpers Ferry, Jefferson County, WV

  8. 7. EXTERIOR OF POWER PLANT BUILDING LOOKING NORTHWEST. DETAIL OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. EXTERIOR OF POWER PLANT BUILDING LOOKING NORTHWEST. DETAIL OF TRASH RACK IN FOREGROUND. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  9. 17. TOP OF TURBINE LOOKING NORTHWEST. SHAFT TO GENERATOR IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. TOP OF TURBINE LOOKING NORTHWEST. SHAFT TO GENERATOR IN CENTER. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  10. 2. VIEW OF POWER PLANT LOOKING SOUTHEAST. Potomac Power ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. VIEW OF POWER PLANT LOOKING SOUTHEAST. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  11. 14. INTERIOR OF POWER PLANT LOOKING SOUTHEAST AT ELECTRICAL PANEL. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. INTERIOR OF POWER PLANT LOOKING SOUTHEAST AT ELECTRICAL PANEL. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  12. 4. NORTH ELEVATION OF POWER PLANT LOOKING SOUTH SOUTHWEST. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. NORTH ELEVATION OF POWER PLANT LOOKING SOUTH SOUTHWEST. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  13. 26. DETAIL VIEW OF THE ADJUSTABLE FIELD RESISTTOR MANUAL CONTROLS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. DETAIL VIEW OF THE ADJUSTABLE FIELD RESISTTOR MANUAL CONTROLS AND SWITCH BOXES. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  14. 36. NORTH ELEVATION FROM ACROSS POTOMAC RIVER IN MARYLAND. Taken ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    36. NORTH ELEVATION FROM ACROSS POTOMAC RIVER IN MARYLAND. Taken by Jet Lowe, HAER staff photographer, September 1980 - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  15. 1. Photocopy of engraved flyer (from the collection of Dr. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Photocopy of engraved flyer (from the collection of Dr. Margaret Ballard, Union, West Virginia) H. Bartsch, engraver late 19th century AERIAL VIEW OF TOWN AND ADVERTISING SLOGANS - Red Sulphur Springs, Route 12, Salt Sulphur Springs, Monroe County, WV

  16. GANTRY SIGNAL EAST OF TOWER AT MILEPOST 203.0, LOOKING WEST, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    GANTRY SIGNAL EAST OF TOWER AT MILEPOST 203.0, LOOKING WEST, EQUIPPED WITH B&O COLOR-POSITION-LIGHT SIGNAL HEAD FOR WESTBOUND TRAINS. - Baltimore & Ohio Railroad, Z Tower, State Route 46, Keyser, Mineral County, WV

  17. SIGNAL BRIDGE WEST OF TOWER AT MILEPOST 203.2, LOOKING WEST, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    SIGNAL BRIDGE WEST OF TOWER AT MILEPOST 203.2, LOOKING WEST, EQUIPPED WITH B&O COLOR-POSITION-LIGHT SIGNAL HEADS FOR EASTBOUND TRAINS. - Baltimore & Ohio Railroad, Z Tower, State Route 46, Keyser, Mineral County, WV

  18. 42 CFR 84.136 - Facepieces, hoods, and helmets; eyepieces; minimum requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... is not distorted by the eyepiece. (b) All eyepieces except those on Types B, BE, C, and CE supplied... Assurance Branch, 1095 Willowdale Road, Morgantown, WV 26505-2888. (c)(1) The eyepieces of AE, BE, and CE...

  19. 27. William E. Barrett, Photographer, August 1975. TRIMMER SAWS LOOKING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    27. William E. Barrett, Photographer, August 1975. TRIMMER SAWS LOOKING BACK FROM SORTING DOCK. SAW BLADES ARE HIDDEN BY HINGED PARTITION. SPIRAL ROLLERS CARRY BOARDS FROM SAWS TO HANDLES. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  20. 1. Photocopied 1974 from Album of Baltimore and Ohio Railroad, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Photocopied 1974 from Album of Baltimore and Ohio Railroad, Witteman Brothers, Smithsonian Institution, 1882. WOODCUT ILLUSTRATION OF TRESTLE WORK, CHEAT RIVER GORGE. - Baltimore & Ohio Railroad, Tray Run Viaduct, Spanning Tray Run, Rowlesburg, Preston County, WV

  1. 13. INTERIOR VIEW OF BLISS #74 1/2 PRESS OPERATED BY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. INTERIOR VIEW OF BLISS #74 1/2 PRESS OPERATED BY JEFF HOHMAN; USED TO TRIM THE EXCESS METAL OR FLASH FROM BLADE END OF POST HOLE DIGGER - Warwood Tool Company, Foot of Nineteenth Street, Wheeling, Ohio County, WV

  2. 2. Photocopied 1974 from The Baltimore and Ohio Railroad and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Photocopied 1974 from The Baltimore and Ohio Railroad and Its Branches, from the Lakes to the Sea, Baltimore, 1872. TRESTLE WORK NEAR ROWLESBURG - UNDER VIEW. - Baltimore & Ohio Railroad, Tray Run Viaduct, Spanning Tray Run, Rowlesburg, Preston County, WV

  3. 2. Photocopied 1972 from Ecole imperiale des ponts et chaussees, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Photocopied 1972 from Ecole imperiale des ponts et chaussees, Collection de Dessins Distribues aus eleves, (n.d. and no place), ORIGINAL FINK TRUSS BRIDGE, 1852. - Baltimore & Ohio Railroad, Fairmont Bridge, Spanning Monongahela River, Fairmont, Marion County, WV

  4. DETAIL OF BEEHIVE COKE OVEN DOOR, LOOKING NORTH; NOTE FIREBRICK ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL OF BEEHIVE COKE OVEN DOOR, LOOKING NORTH; NOTE FIRE-BRICK ARCH AND IRON JAMB AND SILL - Nuttallburg Mine Complex, Coke Ovens, North side of New River, 2.7 miles upstream from Fayette Landing, Lookout, Fayette County, WV

  5. 78 FR 16035 - Qualification of Drivers; Exemption Applications; Vision

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-13

    ... renewable two-year period. They are: Richard D. Carlson (MN) Robert P. Conrad, Sr. (MD) Donald P. Dodson, Jr. (WV) James A. Stoudt (PA) Ralph A. Thompson (KY) The exemptions are extended subject to the...

  6. 1. VIEW NORTH OF GILBERT BRIDGE, PORTAL AND PORTAL CONNECTIONS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. VIEW NORTH OF GILBERT BRIDGE, PORTAL AND PORTAL CONNECTIONS AND BRACING, TRAFFIC DECK - Gilbert Bridge, U.S. Route 52, spanning Guyandotte River near confluence of Gilbert Creek, Gilbert, Mingo County, WV

  7. 3. VIEW NORTH OF GILBERT BRIDGE, TRUSS SEATINGS, BOTTOM MEMBERS, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. VIEW NORTH OF GILBERT BRIDGE, TRUSS SEATINGS, BOTTOM MEMBERS, TRAFFIC DECK SUPPORT SYSTEM - Gilbert Bridge, U.S. Route 52, spanning Guyandotte River near confluence of Gilbert Creek, Gilbert, Mingo County, WV

  8. 32. William E. Barrett, Photographer, 1973. DEADEND WELL WITH WOODEN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    32. William E. Barrett, Photographer, 1973. DEAD-END WELL WITH WOODEN OIL TANK, PIPE ROCKER ARM. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  9. 41. William E. Barrett, Photographer, 1973. MR. WEST'S HOUSE, MR. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    41. William E. Barrett, Photographer, 1973. MR. WEST'S HOUSE, MR. WEST ON PORCH AND THE ARBOR THAT IS OVER 100 YEARS OLD. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  10. 27. Photocopied 1973 from The Rig & Reel Magazine, (March, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    27. Photocopied 1973 from The Rig & Reel Magazine, (March, 1923) p. 5. EARLIER ENDLESS-WIRE TRANSMISSION NOW IN RUINS. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  11. 31. William E. Barrett, Photographer, 1973. WELL WITH POLE DERRICK ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    31. William E. Barrett, Photographer, 1973. WELL WITH POLE DERRICK AND COMPLETE SET OF WHEELS, ROADWAY ACCESS. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  12. 40. William E. Barrett, Photographer, 1973. SHOP, YPOLE, MR. WEST'S ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    40. William E. Barrett, Photographer, 1973. SHOP, Y-POLE, MR. WEST'S HOUSE AND POLE SWELL - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  13. 34. William E. Barrett, Photographer, 1973. ENGINE HOUSE, WIRES FROM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    34. William E. Barrett, Photographer, 1973. ENGINE HOUSE, WIRES FROM IT, AND COMPLETE WELL DERAIL, WHEELS. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  14. 28. Photocopied 1973 from The Rig & Reel Magazine, (March, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    28. Photocopied 1973 from The Rig & Reel Magazine, (March, 1923) p. 2. INTERIOR OF CENTRAL POWERHOUSE AT VOLCANO - NOW DISMANTLED. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  15. 26. Photocopied 1973 from The Rig & Reel Magazine, (March, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. Photocopied 1973 from The Rig & Reel Magazine, (March, 1923) p. 1. TYPICAL WELL HOOK-UP. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  16. 25. Photocopied 1973 from The Rig & Reel Magazine, (March, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    25. Photocopied 1973 from The Rig & Reel Magazine, (March, 1923) p. 1. TYPICAL ENDLESS-WIRE RIG IN VOLCANO. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  17. 46. William E. Barrett, Photographer, 1977. SAME SHOWING MORE ROOF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    46. William E. Barrett, Photographer, 1977. SAME SHOWING MORE ROOF DAMAGE AND NOT QUITE AS WIDE AN ANGLE VIEW. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  18. 3. WEST ELEVATION, SHOWING CHECK WEIGHMAN'S ROOM (LEFT CENTER), CONVEYOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. WEST ELEVATION, SHOWING CHECK WEIGHMAN'S ROOM (LEFT CENTER), CONVEYOR MOTOR ROOM (RIGHT CENTER) AND CONVEYOR (RIGHT), LOOKING SOUTHEAST - Nuttallburg Mine Complex, Headhouse, North side of New River, 2.7 miles upstream from Fayette Landing, Lookout, Fayette County, WV

  19. TOWER, WEST ELEVATION, SHOWING CONNECTION PIPES FOR TURNOUTS 22 (FOREGROUND) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    TOWER, WEST ELEVATION, SHOWING CONNECTION PIPES FOR TURNOUTS 22 (FOREGROUND) AND 24. NOTE “LAZY JACK” TEMPERATURE COMPENSATOR IN FOREGROUND. - Baltimore & Ohio Railroad, Z Tower, State Route 46, Keyser, Mineral County, WV

  20. 75 FR 71462 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-23

    ... Cranberry Resources, LLC Beckley, WV........ 11/01/10 10/25/10 (Company). 74806 Cranberry Hardwoods, Beckley..., TN.. 11/05/10 10/25/10 Company (Company). 74826 Cranberry Lumber Company Newport, OH........ 11/05/10...