Science.gov

Sample records for a4-a parkersburg wv

  1. 75 FR 26793 - Fypon, Ltd., Parkersburg, WV, Including Workers Whose Unemployment Insurance, (UI) Wages Are Paid...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-12

    ... Federal Register on March 5, 2010 (75 FR 10321). At the request of the state, the Department reviewed the... Employment and Training Administration Fypon, Ltd., Parkersburg, WV, Including Workers Whose Unemployment... Leased Workers From Job1 USA, Including Workers Whose Unemployment Insurance, (UI) Wages Are Paid...

  2. 40 CFR 81.70 - Parkersburg (West Virginia)-Marietta (Ohio) Interstate Air Quality Control Region.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Parkersburg (West Virginia)-Marietta... PLANNING PURPOSES Designation of Air Quality Control Regions § 81.70 Parkersburg (West Virginia)-Marietta (Ohio) Interstate Air Quality Control Region. The Parkersburg (West Virginia)-Marietta (Ohio)...

  3. 40 CFR 81.70 - Parkersburg (West Virginia)-Marietta (Ohio) Interstate Air Quality Control Region.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Parkersburg (West Virginia)-Marietta... PLANNING PURPOSES Designation of Air Quality Control Regions § 81.70 Parkersburg (West Virginia)-Marietta (Ohio) Interstate Air Quality Control Region. The Parkersburg (West Virginia)-Marietta (Ohio)...

  4. 40 CFR 81.70 - Parkersburg (West Virginia)-Marietta (Ohio) Interstate Air Quality Control Region.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Parkersburg (West Virginia)-Marietta... PLANNING PURPOSES Designation of Air Quality Control Regions § 81.70 Parkersburg (West Virginia)-Marietta (Ohio) Interstate Air Quality Control Region. The Parkersburg (West Virginia)-Marietta (Ohio)...

  5. 40 CFR 81.70 - Parkersburg (West Virginia)-Marietta (Ohio) Interstate Air Quality Control Region.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Parkersburg (West Virginia)-Marietta... PLANNING PURPOSES Designation of Air Quality Control Regions § 81.70 Parkersburg (West Virginia)-Marietta (Ohio) Interstate Air Quality Control Region. The Parkersburg (West Virginia)-Marietta (Ohio)...

  6. 40 CFR 81.70 - Parkersburg (West Virginia)-Marietta (Ohio) Interstate Air Quality Control Region.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Parkersburg (West Virginia)-Marietta... PLANNING PURPOSES Designation of Air Quality Control Regions § 81.70 Parkersburg (West Virginia)-Marietta (Ohio) Interstate Air Quality Control Region. The Parkersburg (West Virginia)-Marietta (Ohio)...

  7. Characteristics of stria vascularis melanocytes of viable dominant spotting (Wv/Wv) mouse mutants.

    PubMed

    Cable, J; Barkway, C; Steel, K P

    1992-12-01

    The Wv mutation lies in the kinase domain of the proto-oncogene c-kit which is expressed in a variety of cells including neural crest derived melanoblasts. The mutation results in the abnormal migration, proliferation, survival and/or differentiation of melanoblasts. Viable Dominant Spotting (Wv/Wv) mouse mutants have a white coat due to the absence of melanocytes. The majority of these animals have no melanocytes within the stria vascularis and no endocochlear potential (EP). A proportion of homozygous mutants partially escape the effects of the mutation: 47.2% of pinnae and 21% of vestibular regions were pigmented and 10.8% of ears had an EP. All ears with an EP that were available for histology had some pigmentation of the stria. There was no obvious correlation between external and internal spotting in Wv/Wv mice, and asymmetrical pigmentation of the ears was common. Both light and dark intermediate cells (which are derived from melanocytes) were present in the middle and/or basal turns of these cochlear ducts and they appeared to function normally in enabling the stria to produce an EP (although the EP was usually lower than normal). This suggests that the c-kit gene product is needed only during development of the stria, and not for mature melanocyte function because the melanocytes present in the mutant strias were carrying the mutant version of the c-kit gene. Melanocytes were similar in appearance in controls and mutants, except that fewer melanin granules were observed in the strias of Wv/Wv mice. The observations that strial melanocytes with very few melanin granules in Wv/Wv mutants are able to support EP production, together with previous observations that albino animals with strial melanocytes but no melanin have a normal EP, suggest that melanocytes but not melanin are essential for normal strial function.

  8. 75 FR 43 - Modification of Class E Airspace; Beckley, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-04

    ... Memorial Airport, Beckley, WV, in the Federal Register on October 19, 2009 (74 FR 53408), Docket No. FAA... Federal Aviation Administration 14 CFR Part 71 Modification of Class E Airspace; Beckley, WV AGENCY... that modifies Class E airspace at Raleigh County Memorial Airport, Beckley, WV. This rule increases...

  9. 75 FR 42 - Establishment of Class E Airspace; Spencer, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-04

    ... October 19, 2009 (74 FR 53407), Docket No. FAA- 2009-0602; Airspace Docket No. 09-AEA-13. The FAA uses the... Federal Aviation Administration 14 CFR Part 71 Establishment of Class E Airspace; Spencer, WV AGENCY... that establishes Class E Airspace at Spencer, WV. This action enhances the safety and...

  10. 75 FR 68026 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-04

    .... Schumacher, 200 Third Street, A4-A, Parkersburg, WV 26106- 1328, or Robert.Schumacher@bpd.treas.gov . FOR... should be directed to Robert L. Schumacher, Bureau of the Public Debt, 200 Third Street, A4-A..., maintenance, and purchase of services to provide information. Dated: October 28, 2010. Robert L....

  11. 75 FR 48551 - Establishment of Class E Airspace; Williamson, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-11

    ... Register a notice of proposed rulemaking to establish Class E airspace at Williamson, WV (75 FR 26150... Procedures (44 FR 11034; February 26, 1979); and (3) does not warrant preparation of a Regulatory Evaluation..., 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The...

  12. 76 FR 71936 - Upper Deckers Creek Watershed, Preston County, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-21

    ... Natural Resources Conservation Service Upper Deckers Creek Watershed, Preston County, WV AGENCY: Natural... Environmental Quality Guidelines (40 CFR part 1500); and the Natural Resources Conservation Service Guidelines (7 CFR part 650); the Natural Resources Conservation Service, U. S. Department of Agriculture,...

  13. 76 FR 80230 - Amendment of Class E Airspace; Huntington, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-23

    ..., WV (76 FR 64295) Docket No. FAA-2011-1057. Interested parties were invited to participate in this... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does... FR 9565, 3 CFR, 1959-1963 Comp., p. 389. Sec. 71.1 0 2. The incorporation by reference in 14 CFR...

  14. 77 FR 73510 - West Virginia; Disaster #WV-00031

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-10

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION West Virginia; Disaster WV-00031 AGENCY: U.S. Small Business Administration. ACTION: Notice... for the State of West Virginia (FEMA-4093-DR), dated 11/27/2012. Incident: Hurricane Sandy....

  15. 77 FR 17561 - West Virginia Disaster #WV-00023

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-26

    ... ADMINISTRATION West Virginia Disaster WV-00023 AGENCY: Small Business Administration. ACTION: Notice. SUMMARY: This is a Notice of the Presidential declaration of a major disaster for the State of West Virginia..., Marion, Wayne. Contiguous Counties (Economic Injury Loans Only): West Virginia: Boone, Cabell,...

  16. 75 FR 41246 - West Virginia Disaster Number WV-00020

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-15

    ... ADMINISTRATION West Virginia Disaster Number WV-00020 AGENCY: U.S. Small Business Administration. ACTION... of West Virginia (FEMA-1918-DR), dated 06/24/2010. Incident: Severe storms, flooding, mudslides, and... of West Virginia, dated 06/24/2010 is hereby amended to establish the incident period for...

  17. 77 FR 71667 - West Virginia Disaster Number WV-00029

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-03

    ... ADMINISTRATION West Virginia Disaster Number WV-00029 AGENCY: U.S. Small Business Administration. ACTION... of West Virginia (FEMA-4071-DR), dated 09/ 19/2012. Incident: Severe storms and straight-line winds.... SUPPLEMENTARY INFORMATION: The notice of the President's major disaster declaration for the State of...

  18. 77 FR 25225 - West Virginia Disaster Number WV-00027

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-27

    ... ADMINISTRATION West Virginia Disaster Number WV-00027 AGENCY: U.S. Small Business Administration. ACTION... of West Virginia (FEMA--4061--DR), dated 03/22/2012. Incident: Severe storms, flooding, mudslides and... West Virginia, dated 03/22/2012 is hereby amended to include the following areas as adversely...

  19. 75 FR 41245 - West Virginia Disaster Number WV-00018

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-15

    ... ADMINISTRATION West Virginia Disaster Number WV-00018 AGENCY: U.S. Small Business Administration. ACTION... Assistance Only for the State of WEST VIRGINIA (FEMA-1903-DR), dated 04/23/2010. Incident: Severe Winter... disaster declaration for Private Non-Profit organizations in the State of WEST VIRGINIA, dated...

  20. 77 FR 47908 - West Virginia Disaster Number WV-00028

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-10

    ... ADMINISTRATION West Virginia Disaster Number WV-00028 AGENCY: U.S. Small Business Administration. ACTION... Assistance Only for the State of West Virginia (FEMA-4071-DR), dated 07/23/2012. Incident: Severe Storms and... disaster declaration for Private Non-Profit organizations in the State of West Virginia, dated...

  1. 75 FR 41246 - West Virginia Disaster Number WV-00020

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-15

    ... ADMINISTRATION West Virginia Disaster Number WV-00020 AGENCY: U.S. Small Business Administration. ACTION... of West Virginia (FEMA-1918-DR), dated 06/ 24/2010. Incident: Severe storms, flooding, mudslides, and... West Virginia, dated 06/24/2010 is hereby amended to include the following areas as adversely...

  2. 75 FR 35103 - West Virginia Disaster Number WV-00015

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-21

    ... ADMINISTRATION West Virginia Disaster Number WV-00015 AGENCY: Small Business Administration. ACTION: Amendment 1... Only for the State of West Virginia (FEMA-1881-DR), dated 03/02/2010. Incident: Severe winter storm and... Private Non-Profit organizations in the State of West Virginia, dated 03/02/2010, is hereby amended...

  3. 75 FR 20401 - West Virginia Disaster Number WV-00017

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-19

    ... ADMINISTRATION West Virginia Disaster Number WV-00017 AGENCY: U.S. Small Business Administration. ACTION... Assistance Only for the State of West Virginia (FEMA-1893-DR), dated 03/29/2010. Incident: Severe Storms... major disaster declaration for Private Non-Profit organizations in the State of West Virginia, dated...

  4. 75 FR 17176 - West Virginia Disaster #WV-00017

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-05

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION West Virginia Disaster WV-00017 AGENCY: U.S. Small Business Administration. ACTION: Notice... for the State of West Virginia (FEMA-1893-DR), dated 03/29/2010. Incident: Severe Storms,...

  5. 75 FR 24756 - West Virginia Disaster Number WV-00017

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-05

    ... ADMINISTRATION West Virginia Disaster Number WV-00017 AGENCY: U.S. Small Business Administration. ACTION... Assistance Only for the State of West Virginia (FEMA--1893--DR), dated 03/29/2010. Incident: Severe Storms... major disaster declaration for Private Non-Profit organizations in the State of West Virginia, dated...

  6. 75 FR 38155 - West Virginia Disaster #WV-00020

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-01

    ... ADMINISTRATION West Virginia Disaster WV-00020 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a Notice of the Presidential declaration of a major disaster for the State of WEST...Dowell, Mingo, Wyoming. Contiguous Counties (Economic Injury Loans Only): West Virginia: Boone,...

  7. 75 FR 11582 - West Virginia Disaster # WV-00015

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-11

    ... From the Federal Register Online via the Government Publishing Office ] SMALL BUSINESS ADMINISTRATION West Virginia Disaster WV-00015 AGENCY: U.S. Small Business Administration. ACTION: Notice... for the state of West Virginia (FEMA-1881-DR), dated 03/02/2010. Incident: Severe winter storm...

  8. 78 FR 14148 - West Virginia Disaster #WV-00030

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-04

    ... ADMINISTRATION West Virginia Disaster WV-00030 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of West Virginia... adversely affected by the disaster: Primary Counties: Nicholas. Contiguous Counties: West Virginia:...

  9. 78 FR 55770 - West Virginia Disaster #WV-00032

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-11

    ... ADMINISTRATION West Virginia Disaster WV-00032 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a notice of an Administrative declaration of a disaster for the State of West Virginia... adversely affected by the disaster: Primary Counties: Roane. Contiguous Counties: West Virginia:...

  10. 75 FR 17177 - West Virginia Disaster #WV-00016

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-05

    ... ADMINISTRATION West Virginia Disaster WV-00016 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a Notice of the Presidential declaration of a major disaster for the State of West..., Kanawha, Mercer, Raleigh. Contiguous Counties (Economic Injury Loans Only): West Virginia: Boone,...

  11. 77 FR 70204 - West Virginia; Disaster Number WV-00029

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-23

    ... ADMINISTRATION West Virginia; Disaster Number WV-00029 AGENCY: U.S. Small Business Administration. ACTION... of West Virginia (FEMA-4071-DR), dated 09/ 19/2012. Incident: Severe Storms and Straight-line Winds.... SUPPLEMENTARY INFORMATION: The notice of the Presidential disaster declaration for the State of West...

  12. 77 FR 25224 - West Virginia Disaster Number WV-00023

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-27

    ... ADMINISTRATION West Virginia Disaster Number WV-00023 AGENCY: U.S. Small Business Administration. ACTION... of West Virginia (FEMA-4059-DR), dated 03/ 16/2012. Incident: Severe Storms, Tornadoes, Flooding... State of WEST VIRGINIA, dated 03/16/2012 is hereby amended to include the following areas as...

  13. 75 FR 20400 - West Virginia Disaster Number WV-00016

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-19

    ... ADMINISTRATION West Virginia Disaster Number WV-00016 AGENCY: U.S. Small Business Administration. ACTION... of West Virginia (FEMA-1893-DR), dated 03/ 29/2010. Incident: Severe Storms, Flooding, Mudslides, and... the State of West Virginia, dated 03/29/2010 is hereby amended to establish the incident period...

  14. 77 FR 23538 - West Virginia Disaster Number WV-00027

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-19

    ... ADMINISTRATION West Virginia Disaster Number WV-00027 AGENCY: U.S. Small Business Administration. ACTION... of West Virginia (FEMA-4061-DR), dated 03/ 22/2012. Incident: Severe Storms, Flooding, Mudslides, and... of West Virginia, dated 03/22/2012 is hereby amended to establish the incident period for...

  15. 77 FR 20475 - West Virginia Disaster #WV-00025

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-04

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION West Virginia Disaster WV-00025 AGENCY: U.S. Small Business Administration. ACTION: Notice... for the State of West Virginia (FEMA-4061-DR), dated 03/22/2012. Incident: Severe Storms,...

  16. 77 FR 60002 - West Virginia Disaster #WV-00029

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-01

    ... ADMINISTRATION West Virginia Disaster WV-00029 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a Notice of the Presidential declaration of a major disaster for the State of West...; Nicholas; Raleigh. Contiguous Counties (Economic Injury Loans Only): West Virginia: Boone; Braxton;...

  17. 75 FR 38155 - West Virginia Disaster #WV-00021

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-01

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION West Virginia Disaster WV-00021 AGENCY: U.S. Small Business Administration. ACTION: Notice... for the State of WEST VIRGINIA (FEMA-1918-DR), dated 06/24/2010. Incident: Severe Storms,...

  18. 77 FR 45410 - West Virginia Disaster #WV-00028

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-31

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION West Virginia Disaster WV-00028 AGENCY: U.S. Small Business Administration. ACTION: Notice... for the State of West Virginia (FEMA--4071--DR), dated 07/23/2012. Incident: Severe Storms...

  19. 75 FR 41246 - West Virginia Disaster Number WV-00021

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-15

    ... ADMINISTRATION West Virginia Disaster Number WV-00021 AGENCY: U.S. Small Business Administration. ACTION... Assistance Only for the State of West Virginia (FEMA-1918-DR), dated 06/24/2010. Incident: Severe storms... major disaster declaration for Private Non-Profit organizations in the State of West Virginia, dated...

  20. 77 FR 55890 - West Virginia Disaster Number WV-00028

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-11

    ... ADMINISTRATION West Virginia Disaster Number WV-00028 AGENCY: U.S. Small Business Administration. ACTION... Assistance Only for the State of West Virginia (FEMA--4071--DR), dated 07/23/2012. Incident: Severe Storms... disaster declaration for Private Non-Profit organizations in the State of West Virginia, dated...

  1. 77 FR 23538 - West Virginia Disaster Number WV-00025

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-19

    ... ADMINISTRATION West Virginia Disaster Number WV-00025 AGENCY: U.S. Small Business Administration. ACTION... Assistance Only for the State of West Virginia (FEMA-4061-DR), dated 03/22/2012. Incident: Severe storms... major disaster declaration for Private Non-Profit organizations in the State of WEST VIRGINIA, dated...

  2. 78 FR 48537 - West Virginia Disaster # WV-00033

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-08

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION West Virginia Disaster WV-00033 AGENCY: U.S. Small Business Administration. ACTION: Notice... for the State of West Virginia (FEMA-4132-DR), dated 07/26/2013. Incident: Severe Storms and...

  3. 77 FR 19405 - West Virginia Disaster #WV-00027

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-30

    ... ADMINISTRATION West Virginia Disaster WV-00027 AGENCY: U.S. Small Business Administration. ACTION: Notice. SUMMARY: This is a Notice of the Presidential declaration of a major disaster for the State of West... Counties (Economic Injury Loans Only): West Virginia: Boone, Lincoln, Mingo, Wyoming. The Interest...

  4. 75 FR 22871 - West Virginia Disaster # WV-00018

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-30

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION West Virginia Disaster WV-00018 AGENCY: U.S. Small Business Administration. ACTION: Notice... for the State of West Virginia (FEMA-1903-DR), dated 04/23/2010. Incident: Severe winter storms...

  5. 76 FR 9966 - Amendment of Class E Airspace; Charleston, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-23

    ...: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959-1963 Comp., p. 389... Yeager Airport, Charleston, WV (75 FR 65251). Interested parties were invited to participate in this... rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does...

  6. METEOSAT IR and WV channels Fundamental Climate Data Record

    NASA Astrophysics Data System (ADS)

    Roebeling, Rob; John, Viju; Hewison, Tim; Lattanzio, Alessio; Schulz, Joerg

    2015-04-01

    The detection of climate change and analysis of climate variability at inter-annual scales requires long-term, well calibrated observations that are homogenised in time and space. Observations from EUMETSAT's series of Meteosat First Generation (MFG) and Meteosat Second Generation (MSG) geostationary satellites span a period from 1982 to today. Although these satellites provide data for climate analysis at multi-decadal scales, their applicability for such analysis is hampered by heterogeneities in the time series due to successive radiometers having different filter functions and changes in the calibration methodology. EUMETSAT initiated the activity to improve the quality of these data, and generates a Fundamental Climate Data Record (FCDR) of Water Vapour (WV) and Infrared (IR) channel radiances, i.e., a long-term data record of calibrated and quality-controlled sensor data designed to allow the generation of homogeneous products that are accurate and stable enough for climate monitoring. The generation of this FCDR is part of EUMETSATs activities in the European Re-Analysis of global CLIMate observations 2 (ERA-CLIM2) project. We present a method to inter-calibrate the complete time series of WV (6.3 µm) and IR (11.8 µm) channel radiances from MFG-MVIRI and MSG-SEVIRI observations. Our method is based on the principles of the Global Space-based Inter-Calibration System (GSICS). A systematic review of spectral conversion functions, which often dominate the errors, indicates that spectral changes of the WV channel from HIRS/2 to HIRS/3 triples the uncertainty of inter-calibrated METEOSAT WV radiances. We will show that these issues can be circumvented by using HIRS/2, AIRS, and IASI as reference instruments, and thus keeping the uncertainties due to spectral conversion similar throughout the time series. Finally we will present an evaluation of 30 years of recalibrated HIRS, MVIRI and /SEVIRI radiances from the IR and WV channels, and demonstrate their improved

  7. 77 FR 5090 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-01

    ... Bureau of the Public Debt Proposed Collection: Comment Request ACTION: Notice and request for comments... 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A)). Currently the Bureau of the Public Debt within the... the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or...

  8. 77 FR 32179 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-31

    ... Bureau of the Public Debt Proposed Collection: Comment Request ACTION: Notice and request for comments... 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the Bureau of the Public Debt within the... to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328,...

  9. 75 FR 14660 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-26

    ... Bureau of the Public Debt Proposed Collection: Comment Request ACTION: Notice and request for comments... 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A)). Currently the Bureau of the Public Debt within the... Public Debt, Judi Owens, 200 Third Street, A4-A, Parkersburg, WV 26106-1328, or...

  10. 78 FR 149 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-02

    ... Bureau of the Public Debt Proposed Collection: Comment Request ACTION: Notice and request for comments... 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the Bureau of the Public Debt within the... to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328,...

  11. 78 FR 341 - Proposed Information Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-03

    ... Bureau of the Public Debt Proposed Information Collection; Comment Request ACTION: Notice and request for... 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the Bureau of the Public Debt within the... the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or...

  12. 75 FR 14659 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-26

    ... Bureau of the Public Debt Proposed Collection: Comment Request ACTION: Notice and request for comments... of 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A)). Currently the Bureau of the Public Debt within... Debt, Judi Owens, 200 Third Street, A4-A, Parkersburg, WV 26106-1328, or judi.owens@bpd.treas.gov ....

  13. 75 FR 14659 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-26

    ... Bureau of the Public Debt Proposed Collection: Comment Request ACTION: Notice and request for comments... 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the Bureau of the Public Debt within the... to Bureau of the Public Debt, Judi Owens, 200 Third Street, A4-A, Parkersburg, WV 26106-1328, or...

  14. 77 FR 43430 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-24

    ... Bureau of the Public Debt Proposed Collection: Comment Request ACTION: Notice and request for comments... 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the Bureau of the Public Debt within the... comments to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV...

  15. 78 FR 25534 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-01

    ... Bureau of the Public Debt Proposed Collection; Comment Request ACTION: Notice and request for comments... 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the Bureau of the Public Debt within the... the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328, or...

  16. 78 FR 25533 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-01

    ... Bureau of the Public Debt Proposed Collection; Comment Request ACTION: Notice and request for comments... 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the Bureau of the Public Debt within the... to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg, WV 26106-1328,...

  17. Fatal antral ulcer in conventionally fed W/Wv mutant mice given indomethacin by injection.

    PubMed Central

    Yokoyama, M.; Tomoi, M.; Taguchi, T.; Nakano, T.; Asai, H.; Ono, T.; Kitamura, Y.

    1985-01-01

    Antral ulcers develop spontaneously in (WB X C57BL/6)F1-W/Wv mice. Most W/Wv mice with severe ulcers die within 3 months after birth. When healthy-looking W/Wv mice were selected at 4 months of age, 80-90% of them were free from the ulcer. Even if the ulcer was present, it was small. The authors compared the susceptibility of such healthy-looking W/Wv mice to ulcerogenic treatments with that of the congenic +/+ mice. Stress caused development of fundic erosions in both W/Wv and +/+ mice. The susceptibility of the W/Wv mice to either cold or water-immersed stress was not higher than that of the +/+ mice. Topical administration of aspirin produced erosions in both fundus and antrum. The susceptibility of W/Wv mice to aspirin was comparable to that of the +/+ mice in either the starved or the fed condition. Subcutaneous injection of indomethacin produced both fundic erosions and antral ulcers in the starved condition, but it produced only antral ulcers in the conventionally fed condition. The susceptibility of the starved W/Wv mice to indomethacin was not higher than that of the starved +/+ mice. In contrast, the fed W/Wv mice were significantly more susceptible to indomethacin than the fed +/+ mice. A considerable proportion of the fed W/Wv mice died of blood loss from the ulcer within 24 hours. The size of the ulcer of the W/Wv mice was significantly larger than that of the +/+ mice. Both genetic and feeding conditions seem to determine the susceptibility to indomethacin. Images Figure 3 Figure 4 PMID:3860014

  18. 33 CFR 165.822 - Safety Zone; Fireworks Display, Kanawha River, WV.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 33 Navigation and Navigable Waters 2 2014-07-01 2014-07-01 false Safety Zone; Fireworks Display... Safety Zone; Fireworks Display, Kanawha River, WV. (a) Safety zones. The following areas are designated... Virginia Special Olympics Fireworks Display Between mile 57.9 and 58.9, Charlestown, WV First Friday...

  19. 33 CFR 165.822 - Safety Zone; Fireworks Display, Kanawha River, WV.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 33 Navigation and Navigable Waters 2 2013-07-01 2013-07-01 false Safety Zone; Fireworks Display... Safety Zone; Fireworks Display, Kanawha River, WV. (a) Safety zones. The following areas are designated... Virginia Special Olympics Fireworks Display Between mile 57.9 and 58.9, Charlestown, WV First Friday...

  20. 33 CFR 165.822 - Safety Zone; Fireworks Display, Kanawha River, WV.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Safety Zone; Fireworks Display... Safety Zone; Fireworks Display, Kanawha River, WV. (a) Safety zones. The following areas are designated... Virginia Special Olympics Fireworks Display Between mile 57.9 and 58.9, Charlestown, WV First Friday...

  1. 33 CFR 165.822 - Safety Zone; Fireworks Display, Kanawha River, WV.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 33 Navigation and Navigable Waters 2 2012-07-01 2012-07-01 false Safety Zone; Fireworks Display... Safety Zone; Fireworks Display, Kanawha River, WV. (a) Safety zones. The following areas are designated... Virginia Special Olympics Fireworks Display Between mile 57.9 and 58.9, Charlestown, WV First Friday...

  2. Efficacy of a topical application of Certifect® (fipronil 6.26% w/v, amitraz 7.48% w/v, (S)-methoprene 5.63% w/v) for the treatment of canine generalized demodicosis

    PubMed Central

    Fourie, Josephus; Dumont, Pascal; Halos, Lénaïg; Beugnet, Frederic; Pollmeier, Matthias

    2013-01-01

    The efficacy of the treatment with Certifect ® (containing fipronil 6.26% w/v, amitraz 7.48% w/v, (S)-methoprene 5.63% w/v) applied topically was assessed in 18 dogs diagnosed with clinical generalized demodicosis. Three treatment regimens were compared over a 3-month period. Starting at Day 0, dogs were treated monthly (group 1) or every two weeks (group 2) with the combination of fipronil, amitraz, and (S)-methoprene or with monthly topical applications of the combination of amitraz and metaflumizone (group 3, reference treatment). Clinical examinations including deep skin scrapings were performed every month in order to evaluate the resolution of clinical signs and the reduction in mite counts. On Day 84, the percentage reduction of mite counts in group 1 was 99.8%, whereas no Demodex canis could be detected in groups 2 and 3 (i.e. 100% parasitological efficacy). As a result of the Demodex mite count reduction, the skin condition of the dogs improved significantly in all groups. This study illustrates, that both monthly and bi-weekly treatments with Certifect were effective in treating dogs with generalized demodicosis over a 3-month period. PMID:24256940

  3. Efficacy of a topical application of Certifect® (fipronil 6.26% w/v, amitraz 7.48% w/v, (S)-methoprene 5.63% w/v) for the treatment of canine generalized demodicosis.

    PubMed

    Fourie, Josephus; Dumont, Pascal; Halos, Lénaïg; Beugnet, Frederic; Pollmeier, Matthias

    2013-01-01

    The efficacy of the treatment with Certifect ® (containing fipronil 6.26% w/v, amitraz 7.48% w/v, (S)-methoprene 5.63% w/v) applied topically was assessed in 18 dogs diagnosed with clinical generalized demodicosis. Three treatment regimens were compared over a 3-month period. Starting at Day 0, dogs were treated monthly (group 1) or every two weeks (group 2) with the combination of fipronil, amitraz, and (S)-methoprene or with monthly topical applications of the combination of amitraz and metaflumizone (group 3, reference treatment). Clinical examinations including deep skin scrapings were performed every month in order to evaluate the resolution of clinical signs and the reduction in mite counts. On Day 84, the percentage reduction of mite counts in group 1 was 99.8%, whereas no Demodex canis could be detected in groups 2 and 3 (i.e. 100% parasitological efficacy). As a result of the Demodex mite count reduction, the skin condition of the dogs improved significantly in all groups. This study illustrates, that both monthly and bi-weekly treatments with Certifect were effective in treating dogs with generalized demodicosis over a 3-month period.

  4. A novel WV film for fast-response-time OCB-LCD

    NASA Astrophysics Data System (ADS)

    Matsubara, Ryota; Ito, Yoji; Nakamura, Shun; Mori, Hiroyuki; Mihayashi, Keiji

    2006-02-01

    We have successfully developed and commercialized an optical compensation film for OCB-LCD mode (OCB-WV film). OCB-LCD mode is known to have a very fast optical response time and makes next-generation fast-response LCD-TVs possible and free from image blurring. The OCB-WV film, which has a structure composed with TAC (triacetyl cellulose) film and PDM (polymerized discotic material) layer, can realize the wide viewing angle of OCB-cell. In order to provide the best performance of OCB-cell, we optimized an optical parameter of not only WV film but also OCB cell by a numerical simulation. In this paper, we will discuss a concept of its optimization, which provide excellent results of a numerical simulation.

  5. Effect of ultraviolet irradiation on mast cell-deficient W/Wv mice

    SciTech Connect

    Ikai, K.; Danno, K.; Horio, T.; Narumiya, S.

    1985-07-01

    The effect of UV irradiation on the skin was investigated in (WB-W/+) X (C57BL/6J-Wv/+)F1-W/Wv mice, which are genetically deficient in tissue mast cells. Their congenic littermates (+/+) and normal albino mice (ICR or BALB/c) were used as controls. Mice were irradiated with 500 mJ/cm2 of UVB and the increment of ear thickness was measured before and 6, 12, and 24 h after irradiation. Ear swelling in W/Wv mice at 12 and 24 h after irradiation was significantly smaller than that in +/+ and ICR mice. In contrast, the number of sunburn cells formed 24 h after UVB irradiation (200 or 500 mJ/cm2) was similar in W/Wv, +/+ and ICR mice. On the other hand, when mice were treated with 8-methoxy-psoralen (0.5%) plus UVA irradiation (4 J/cm2) (topical PUVA), ears of W/Wv and BALB/c mice, which were both white in color, were thickened similarly 72 h after treatment, but less swelling was observed in +/+ mice, which were black in skin color. The amount of prostaglandin D2 (PGD2) in ears, determined by radioimmunoassay specific for PGD2, was elevated 3-fold in +/+ and ICR mice at 3 h after irradiation with 500 mJ/cm2 of UVB in comparison with basal level without irradiation. However, such elevation was not observed in W/Wv mice. These results suggest that mast cells play an important role in UVB-induced inflammation, and PGs from mast cells are responsible at least in part for the development of this reaction. However, neither mast cells nor PGs contribute to the sunburn cell formation and ear swelling response by PUVA treatment.

  6. 75 FR 56469 - Safety Zone; Ohio River, Wheeling, WV, Wheeling Heritage Port Sternwheel Foundation Fireworks...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-16

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; Ohio River, Wheeling, WV, Wheeling Heritage... marine traffic during the Wheeling Heritage Port Sternwheel Foundation fireworks display. Entry into the... traffic during the Wheeling Heritage Port Sternwheel Foundation fireworks display that will occur in...

  7. 77 FR 44684 - American Woodmark Corporation, Moorefield, WV; Notice of Negative Determination on Reconsideration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-30

    ... Employment and Training Administration American Woodmark Corporation, Moorefield, WV; Notice of Negative... Register on June 6, 2012 (77 FR 33491). The workers are engaged in employment related to the production of... initial investigation resulted in a negative determination based on the findings that worker...

  8. 76 FR 40402 - Matthews International Corporation, Bronze Division, Kingwood, WV; Notice of Negative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-08

    ..., Kingwood, WV; Notice of Negative Determination on Reconsideration On January 28, 2011, the Department of..., 2011 (76 FR 7584). Workers were engaged in the production of cast bronze memorial products. The initial investigation resulted in a negative determination based on the findings that, during the relevant period,...

  9. 78 FR 3964 - Request for Public Comment, Raleigh County Memorial Airport, Beckley, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-17

    ... request in a conservation easement for wildlife enhancement, with no adverse impact to the airport. Land... Federal Aviation Administration Request for Public Comment, Raleigh County Memorial Airport, Beckley, WV AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Request for public comment. SUMMARY:...

  10. 77 FR 38376 - Request for Public Comment, Raleigh County Memorial Airport, Beckley, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-27

    ... approximately 549.6 acres of a `surface rights only' release to be sold and land then placed in a Conservation... Federal Aviation Administration Request for Public Comment, Raleigh County Memorial Airport, Beckley, WV AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Request for public comment. SUMMARY:...

  11. Fabrication and characterization of MCC approved testing material: ATM-WV/205 glass

    SciTech Connect

    Maupin, G.D.; Bowen, W.M.; Daniel, J.L.

    1988-08-01

    The ATM-WV/205 glass was produced in accordance with PNL's QA Manual for License-Related Programs, MCC technical procedures, and MCC QA Plan that were in effect during the course of this work. The method and procedure to be used in the fabrication and characterization of the ATM-WV/205 glass were specified in two run plans for glass preparation and a characterization plan. The ATM-WV/205 glass meets all specifications. The elemental composition and oxidation state of the glass are within the sponsor's specifications. Visually, the ATM-WV/205 glass bars appear uniformly glassy and generally without exterior features. Microscopic examination and x-ray diffraction revealed low (about 0.5 wt %) concentrations of 3-..mu..m iron chrome spinel crystals and 1-..mu..m ruthenium inclusions scattered randomly throughout the glassy matrix. Closed porosity, with pores ranging in diameter from 20 to 135 ..mu..m, was observed in all samples. 3 refs., 10 figs., 21 tabs.

  12. Exploring Climate Science with WV Educators: A Regional Model for Teacher Professional Development

    NASA Astrophysics Data System (ADS)

    Ruberg, L. F.; Calinger, M.

    2014-12-01

    The National Research Council Framework for K-12 Science Literacy reports that children reared in rural agricultural communities, who experience regular interactions with plants and animals, develop more sophisticated understanding of ecology and biological systems than do urban and suburban children of the same age. West Virginia (WV) is a rural state. The majority of its residents live in communities of fewer than 2,500 people. Based on the features of the population being served and their unique strengths, this presentation focuses on a regional model for teacher professional development that addresses agricultural and energy vulnerabilities and adaptations to climate change in WV. The professional development model outlined shows how to guide teachers to use a problem-based learning approach to introduce climate data and analysis techniques within a scenario context that is locally meaningful. This strategy engages student interest by focusing on regional and community concerns. Climate science standards are emphasized in the Next Generation Science Standards, but WV has not provided its teachers with appropriate instructional resources to meet those standards. The authors addressed this need by offering a series of climate science education workshops followed by online webinars offered to WV science educators free of charge with funding by the West Virginia Space Grant Consortium. The authors report on findings from this series of professional development workshops conducted in partnership with the West Virginia Science Teachers Association. The goal was to enhance grades 5-12 teaching and learning about climate change through problem-based learning. Prior to offering the climate workshops, all WV science educators were asked to complete a short questionnaire. As Figure 1 shows, over 40% of the teacher respondents reported being confident in teaching climate science content. For comparison post workshops surveys measure teacher confidence in climate science

  13. Global deletion of Trp53 reverts ovarian tumor phenotype of the germ cell-deficient white spotting variant (Wv) mice.

    PubMed

    Cai, Kathy Qi; Wang, Ying; Smith, Elizabeth R; Smedberg, Jennifer L; Yang, Dong-Hua; Yang, Wan-Lin; Xu, Xiang-Xi

    2015-01-01

    White spotting variant (Wv) mice are spontaneous mutants attributed to a point mutation in the c-Kit gene, which reduces the tyrosine kinase activity to around 1% and affects the development of melanocytes, mast cells, and germ cells. Homozygous mutant mice are sterile but can live nearly a normal life span. The female Wv mice have a greatly reduced ovarian germ cell and follicle reserve at birth, and the remaining follicles are largely depleted soon after the females reach reproductive stage at around 7 weeks of age. Consequently, ovarian epithelial tumors develop in 100% of Wv females by 3 to 4 months of age. These tumors, called tubular adenomas, are benign but can become invasive in older Wv mice. We tested if additional genetic mutation(s) could convert the benign ovarian epithelial tumors to malignant tumors by crossing the Wv mutant into the Trp53 knockout background. Surprisingly, we found that global deletion of Trp53 suppressed the development of ovarian tubular adenomas in Wv mice. The ovaries of Wv/Wv; Trp53 (-/-) mice were covered by a single layer of surface epithelium and lacked excessive epithelial proliferation. Rather, the ovaries contained a small number of follicles. The presence of ovarian follicles and granulosa cells, as indicated by Pgc7 and inhibin-alpha expression, correlated with the absence of epithelial lesions. A reduction of Pten gene dosage, as in Wv/Wv; Pten (+/-) mice, produced a similar, though less dramatic, phenotype. We conclude that deletion of Trp53 prolongs the survival of ovarian follicles in Wv mice and consequently prevents the proliferation of ovarian epithelial cells and development of ovarian tubular adenomas. The results suggest that various cell types within the ovary communicate and mutually modulate, and an intact tissue environment is required to ensure homeostasis of ovarian surface epithelial cells. Especially, the current finding emphasizes the importance of ovarian follicles in suppressing the hyperplastic

  14. Scoping Study for Demand Respose DFT II Project in Morgantown, WV

    SciTech Connect

    Lu, Shuai; Kintner-Meyer, Michael CW

    2008-06-06

    This scoping study describes the underlying data resources and an analysis tool for a demand response assessment specifically tailored toward the needs of the Modern Grid Initiatives Demonstration Field Test in Phase II in Morgantown, WV. To develop demand response strategies as part of more general distribution automation, automated islanding and feeder reconfiguration schemes, an assessment of the demand response resource potential is required. This report provides the data for the resource assessment for residential customers and describes a tool that allows the analyst to estimate demand response in kW for each hour of the day, by end-use, season, day type (weekday versus weekend) with specific saturation rates of residential appliances valid for the Morgantown, WV area.

  15. 16. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. STILES RESIDENCE, THORNHILL FARM. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  16. 1. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. VIEW LOOKING SOUTH. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  17. 9. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. VIEW LOOKING NORTH. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  18. 5. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1880. VOLCANO TOWN HALL. BLACKLIN HOUSE AT LEFT. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  19. 19. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. THE OLD STILES HOUSE, LOOKING WEST. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  20. 17. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. THE OLD STILES HOUSE LOOKING EAST. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  1. 14. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. MOUNT FARM OIL COMPANY. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  2. 7. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1880's. VOLCANO LITTLE THEATRE GUILD. SOME CAST. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  3. 12. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. THORNHILL STORE. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  4. Inter-calibration of METEOSAT IR and WV channels using HIRS

    NASA Astrophysics Data System (ADS)

    Roebeling, R.; Schulz, J.; Hewison, T.; Theodore, B.

    2012-04-01

    The detection of climate change and analysis of climate variability at inter-annual scales requires long-term, well calibrated observations that are homogenized in time and space. Observations from EUMETSAT's series of Meteosat First and Second Generation geostationary satellites span a period from 1982 to today for satellites operated over the Atlantic Ocean (sub-satellite longitude 0 degrees), and from 1997 to today for satellites operated over the Indian Ocean. Although these satellites provide data for climate analysis at multi-decadal scales, their applicability for such analysis is hampered by heterogeneities in the time series due to successive radiometers having different filter functions and changes in the calibration methodology. To improve the quality of these time series EUMETSAT has initiated an activity to inter-calibrate their data to community references, following the principles of the Global Space-based Inter-Calibration System (GSICS). We present the strategy to inter-calibrate the complete time series of Water Vapour (WV, 6.3 µm) and Infrared (IR, 11.8 µm) channel radiances from the MVIRI instrument on Meteosat First Generation and the SEVIRI instrument on Meteosat Second Generation. Two different inter-calibration methods are evaluated i.e., (1) inter-calibrate to a homogenised time series of HIRS observations, and (2) inter-calibrate using the so called double differencing methodology. The latter method compares, for instance, observations from two Meteosat instruments to observations of one HIRS instrument, and then calculates the difference between the two Meteosat instruments, or vice versa. Both methods are validated against reference observations, for which observations from the IASI instrument are used. In addition, the stability of the HIRS on Metop is investigated with Metop IASI observations. We have analysed the uncertainties introduced in both methods by changes in filter functions, collocation scene variability, instrument noise

  5. W-V flap: a new technique for reconstruction of female distal urethral stricture using vestibular mucosa.

    PubMed

    Dalela, Diwakar; Gupta, Piyush; Dalela, Disha; Govil, Tuhina

    2016-01-01

    A premenopausal woman having a totally occlusive distal urethral stricture, with suprapubic catheter (SPC) in situ, was referred to us for a definitive procedure. On discussion of the treatment options, the patient refused for a buccal or vaginal flap procedure. Thus, a local W-V flap was fashioned from the periurethral vestibular mucosa with seemingly excellent results, both in terms of resolution of her symptoms and a forwardly directed stream of urine without incontinence. PMID:27170612

  6. Spatial unmixing for environmental impact monitoring of mining using UAS and WV-2

    NASA Astrophysics Data System (ADS)

    Delalieux, S.; Livens, S.; Goossens, M.; Reusen, I.; Tote, C.

    2012-04-01

    The three principal activities of the mineral resources mining industry - mining, mineral processing and metallurgical extraction - all produce waste. The environmental impact of these activities depends on many factors, in particular, the type of mining and the size of the operation. The effects of the mining (extraction) stage tend to be mainly local, associated with surface disturbance, the production of large amounts of solid waste material, and the spread of chemically reactive particulate matter to the atmosphere and hydrosphere. Many studies have shown the potential of remote sensing for environmental impact monitoring, e.g., [1]. However, its applicability has been limited due to the inherent spatial-spectral and temporal trade-off of most sensors. More recently, miniaturization of sensors makes it possible to capture color images from unmanned aerial systems (UAS) with a very high spatial resolution. In addition, the UAS can be deployed in a very flexible manner, allowing high temporal resolution imaging. More detailed spectral information is available from multispectral images, albeit at lower spatial resolution. Combining both types of images using image fusion can help to overcome the spatial-spectral trade-off and provide a new tool for more detailed monitoring of environmental impacts. Within the framework of the ImpactMin project, funded by the Framework Programme 7 of the European Commission, the objective of this study is to implement and apply the spatial unmixing algorithm, as proposed by [2], on images of the 'Vihovici Coal Mine' area, located in the Mostar Valley, Bosnia and Herzegovina. A WorldView2 (WV2) satellite image will be employed, which provides 8-band multispectral data at a spatial resolution of 2m. High spatial resolution images, obtained by a SmartPlanes UAS, will provide RGB data with 0.05m spatial resolution. The spatial unmixing technique is based on the idea that a linear mixing model can be used to perform the downscaling of

  7. U.S. DOE Industrial Technologies Program – Technology Delivery Plant-Wide Assessment at PPG Industries, Natrium, WV

    SciTech Connect

    Lester, Stephen R.; Wiethe, Jeff; Green, Russell; Guice, Christina; Gopalakrishnan, Bhaskaran; Turton, Richard

    2007-09-28

    PPG and West Virginia University performed a plantwide energy assessment at the PPG’s Natrium, WV chemical plant, an energy-intensive manufacturing facility producing chlor-alkali and related products. Implementation of all the assessment recommendations contained in this report could reduce plant energy consumption by 8.7%, saving an estimated 10,023,192 kWh/yr in electricity, 6,113 MM Btu/yr in Natural Gas, 401,156 M lb/yr in steam and 23,494 tons/yr in coal and reduce carbon dioxide emissions by 241 mm lb/yr. The total cost savings would amount to approximately $2.9 mm/yr. Projects being actively implemented will save $1.7 mm/yr; the remainder are undergoing more detailed engineering study.

  8. Clonal contributions of small numbers of retrovirally marked hematopoietic stem cells engrafted in unirradiated neonatal W/Wv mice.

    PubMed

    Capel, B; Hawley, R; Covarrubias, L; Hawley, T; Mintz, B

    1989-06-01

    Mice were repopulated with small numbers of retrovirally marked hematopoietic cells operationally definable as totipotent hematopoietic stem cells, without engraftment of cells at later stages of hematopoiesis, in order to facilitate analysis of stem cell clonal histories. This result depended upon the use of unirradiated W/Wv newborn recipients. Before transplantation, viral integration markers were introduced during cocultivation of fetal liver or bone marrow cells with helper cell lines exporting defective recombinant murine retroviruses of the HHAM series. Omission of selection in culture [although the vector contained the bacterial neomycin-resistance (neo) gene] also limited the proportion of stem cells that were virally labeled. Under these conditions, engraftment was restricted to a small population of marked and unmarked normal donor stem cells, due to their competitive advantage over the corresponding defective cells of the mutant hosts. A relatively simple and coherent pattern emerged, of one or a few virally marked clones, in contrast to previous studies. In order to establish the totipotent hematopoietic stem cell identity of the engrafted cells, tissues were sampled for viral and inbred-strain markers for periods close to one year after transplantation. The virally labeled clones were characterized as stem cell clones by their extensive self-renewal and by formation of the wide range of myeloid and lymphoid lineages tested. Results clearly documented concurrent contributions of cohorts of stem cells to hematopoiesis. A given stem cell can increase or decrease its proliferative activity, become completely inactive or lost, or become active after a long latent period. The contribution of a single clone present in a particular lineage was usually between 5% and 20%. PMID:2567516

  9. 11. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. JOHN SHAFFER'S STORE AND JOHN WILSON'S BOWLING ALLEY AND SALOON IN FOREGROUND. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  10. 6. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. STAGE, VOLCANO TOWN HALL. OLD GLORY, GETTING THE WORST OF IT. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  11. 10. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV. EPISCOPAL CHURCH AND GATES RESIDENCE AT LEFT (n.d.). - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  12. 23. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    23. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1897. TAKEN AT WATER TANKS NEAR THE HIGH TRESTLE. BOB FLEMING-ENGINEER, WILSH (?) ROLLINS-FIREMAN, OTH (?) COLLINS-PASSENGER (WITH CANE). - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  13. 18. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1998. THIS ENGINE HAD CAB KNOCKED OFF AND TIRES USED ON OTHER ENGINE, SO JOHN NOON AND PAT O'BRIEN WERE SCRAPING IT. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  14. 4. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. CORNER OF THORNHILL STORE AND TOWN HALL. MRS. GATES AND JOHN SCHAFFER. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  15. 2. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1898. LARGE TANK, VOLOCANO STATION AND BAND HOUSE, AFTER THE RR WAS DISMANTLED. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  16. 13. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. VOLCANO SCHOOL HOUSE, ME. CHURCH IN WOODS AT LEFT. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  17. 15. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, UP THE HILL, SOUTH OF THE TOWN (n.d.). - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  18. 3. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV. LOOKING DOWN THE CREEK, WEST BACK OF THE STORES, BEFORE THE FIRE (n.d.). - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  19. 22. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1898. TANK, VOLCANO PUMPING STATION, AND BARNE HOUSE STILL STANDING AND IN USE. THIS SHOWS THE OLD RR LINE. (1934 CAPTION). - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  20. 20. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. RESIDENCE OF E.W. STAPLES AND DR. W.H. SHARP. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  1. 8. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. INTERIOR VOLCANO TOWN HALL FROM STAGE SHOWING RAISED SEATS. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  2. 21. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV. 'JOHN NOON L(*(. SAYS HE DROVE THE FIRST SPIKE AND I SAW HIM PULL THE LAST ONE AT VOLCANO JUNCTION' SBS. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  3. 24. Photocopied 1973 from original owned by Albert M. Stiles, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    24. Photocopied 1973 from original owned by Albert M. Stiles, Jr., Parkersburg, WV, 1907. JIM RIDGE'S CARPENTER SHOP, LOOKING UP THE CREEK, EAST. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  4. Pyloric Sphincter Dysfunction in nNOS−/− and W/Wv Mutant Mice: Animal Models of Gastroparesis and Duodeno-gastric Reflux

    PubMed Central

    Sivarao, Digavalli V.; Mashimo, Hiroshi; Goyal, Raj K.

    2009-01-01

    Background and & Aims Nitrergic nerves and interstitial cells of Cajal (ICC) have been implicated in the regulation of pyloric motility. The purpose of these studies was to define their roles in pyloric function in vivo. Methods Pyloric sphincter manometry was performed in wild type (WT) controls, neuronal nitric oxide synthase deficient (nNOS−/−) and ICC deficient W/Wv mice, and the effect of deafferented cervical vagal stimulation was examined. Results Mice showed a distinct ~ 0.6 mm wide zone of high pressure at the antro-duodenal junction, representing the pyloric sphincter. In WT, the pylorus exhibited tonic active pressure of 12.4±1.6 mm Hg with superimposed phasic contractions. The motility indices, minute motility index (MMI) and the total myogenic activity (TMA) were reduced by vagal stimulation and the reduction was antagonized by nitric oxide synthase inhibitor, L-NAME. In nNOS−/− mice, pyloric basal tone, MMI and TMA were not significantly different from the controls, but vagal stimulation paradoxically increased pyloric motility. In contrast, the W/Wv mice had significantly reduced resting pyloric pressure that was suppressed by vagal stimulation in an L-NAME-sensitive manner. The stomachs of fasted nNOS−/− mice showed solid food residue and bezoar formation, while W/Wv mice showed bile reflux. Conclusion (1) In nNOS−/− mice, loss of nitrergic pyloric inhibition leads to gastric stasis and bezoars; (2) In contrast, basal pyloric hypotension with normal nitrergic inhibition predisposes W/Wv mice to duodeno-gastric bile reflux. PMID:18640116

  5. Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W.

    PubMed Central

    Nocka, K; Tan, J C; Chiu, E; Chu, T Y; Ray, P; Traktman, P; Besmer, P

    1990-01-01

    The proto-oncogene c-kit encodes a transmembrane tyrosine protein kinase receptor for an unknown ligand and is allelic with the murine white-spotting locus (W). Mutations at the W locus affect various aspects of hematopoiesis, the proliferation and migration of primordial germ cells and melanoblasts during development. The original W mutation and W37 are severe lethal mutations when homozygous. In the heterozygous state the W mutation has a weak phenotype while W37 has dominant characteristics. Wv and W41 are weak W mutations with dominant characteristics. We have characterized the molecular basis of these four W mutations and determined their effects on mast cell differentiation by using a fibroblast/mast cell co-culture assay. We show that W37, Wv and W41 are the result of missense mutations in the kinase domain of the c-kit coding sequence (W37 E----K at position 582; Wv T----M position 660 and W41 V----M position 831), which affect the c-kit associated tyrosine kinase to varying degrees. The c-kit protein products in homozygous mutant mast cells are expressed normally, although the 160 kd cell membrane form of the c-kitW37 protein displays accelerated turnover characteristics. The W mutation is the result of a 78 amino acid deletion which includes the transmembrane domain of the c-kit protein. A 125 kd c-kit protein was detected in homozygous W/W mast cells which lacks kinase activity and is not expressed on the cell surface.(ABSTRACT TRUNCATED AT 250 WORDS) Images Fig. 2. Fig. 3. Fig. 5. PMID:1693331

  6. Category and perceptual interference in second-language phoneme learning: an examination of English /w/-/v/ learning by Sinhala, German, and Dutch speakers.

    PubMed

    Iverson, Paul; Ekanayake, Dulika; Hamann, Silke; Sennema, Anke; Evans, Bronwen G

    2008-10-01

    The present study investigated the perception and production of English /w/ and /v/ by native speakers of Sinhala, German, and Dutch, with the aim of examining how their native language phonetic processing affected the acquisition of these phonemes. Subjects performed a battery of tests that assessed their identification accuracy for natural recordings, their degree of spoken accent, their relative use of place and manner cues, the assimilation of these phonemes into native-language categories, and their perceptual maps (i.e., multidimensional scaling solutions) for these phonemes. Most Sinhala speakers had near-chance identification accuracy, Germans ranged from chance to 100% correct, and Dutch speakers had uniformly high accuracy. The results suggest that these learning differences were caused more by perceptual interference than by category assimilation; Sinhala and German speakers both have a single native-language phoneme that is similar to English /w/ and /v/, but the auditory sensitivities of Sinhala speakers make it harder for them to discern the acoustic cues that are critical to /w/-/v/ categorization.

  7. Category and perceptual interference in second-language phoneme learning: an examination of English /w/-/v/ learning by Sinhala, German, and Dutch speakers.

    PubMed

    Iverson, Paul; Ekanayake, Dulika; Hamann, Silke; Sennema, Anke; Evans, Bronwen G

    2008-10-01

    The present study investigated the perception and production of English /w/ and /v/ by native speakers of Sinhala, German, and Dutch, with the aim of examining how their native language phonetic processing affected the acquisition of these phonemes. Subjects performed a battery of tests that assessed their identification accuracy for natural recordings, their degree of spoken accent, their relative use of place and manner cues, the assimilation of these phonemes into native-language categories, and their perceptual maps (i.e., multidimensional scaling solutions) for these phonemes. Most Sinhala speakers had near-chance identification accuracy, Germans ranged from chance to 100% correct, and Dutch speakers had uniformly high accuracy. The results suggest that these learning differences were caused more by perceptual interference than by category assimilation; Sinhala and German speakers both have a single native-language phoneme that is similar to English /w/ and /v/, but the auditory sensitivities of Sinhala speakers make it harder for them to discern the acoustic cues that are critical to /w/-/v/ categorization. PMID:18823213

  8. 31 CFR 351.45 - What happens if I purchase definitive Series EE savings bonds in excess of the maximum annual...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... BUREAU OF THE PUBLIC DEBT OFFERING OF UNITED STATES SAVINGS BONDS, SERIES EE Definitive Series EE Savings... obtain instructions for adjustment of the excess from us at the following address: email at savbonds@bpd.treas.gov, or writing to Bureau of the Public Debt, Parkersburg, WV 26106-1328....

  9. 31 CFR 351.45 - What happens if I purchase definitive Series EE savings bonds in excess of the maximum annual...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... BUREAU OF THE PUBLIC DEBT OFFERING OF UNITED STATES SAVINGS BONDS, SERIES EE Definitive Series EE Savings... obtain instructions for adjustment of the excess from us at the following address: email at savbonds@bpd.treas.gov, or writing to Bureau of the Public Debt, Parkersburg, WV 26106-1328....

  10. 77 FR 32179 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-31

    ... Department of the Treasury is soliciting comments concerning the Certificate of Identity. DATES: Written..., Parkersburg, WV 26106-1328, (304) 480-8150. SUPPLEMENTARY INFORMATION: Title: Certificate of Identity. OMB... identity of the owner of the United States Savings Securities. Current Actions: None. Type of...

  11. Diluting ferric carboxymaltose in sodium chloride infusion solution (0.9% w/v) in polypropylene bottles and bags: effects on chemical stability

    PubMed Central

    Philipp, Erik; Braitsch, Michaela; Bichsel, Tobias; Mühlebach, Stefan

    2016-01-01

    Objectives This study was designed to assess the physicochemical stability of colloidal ferric carboxymaltose solution (Ferinject) when diluted and stored in polypropylene (PP) bottles and bags for infusion. Methods Two batches of ferric carboxymaltose solution (Ferinject) were diluted (500 mg, 200 mg and 100 mg iron in 100 mL saline) in PP bottles or bags under aseptic conditions. The diluted solutions were stored at 30°C and 75%±5% relative humidity (rH) for 72 h, and samples were withdrawn aseptically at preparation and after 24 h, 48 h and 72 h. Multiple parameters were used to test stability-related measures (pH, total iron and iron (II) content, molecular weight range determination, microbial contamination and particles count ≥10 μm). Results Overall, Ferinject diluted in 0.9% (w/v) NaCl solution and stored in PP bottles and bags was stable within the specifications for the complex and the acceptability limits set for all assays. In both containers, total iron content remained stable, within 10% of the theoretical iron content, and levels of iron (II) remained far below the threshold of acceptability. All preparations were free from sediments, particle numbers were acceptable and there was no microbial contamination. The molecular weight distribution and polydispersity index were also acceptable. Conclusions Under the tested experimental conditions, colloidal ferric carboxymaltose solution (Ferinject) diluted in saline in PP infusion bottles or bags demonstrated physical and chemical stability for up to 72 h at 30°C and 75% rH. Because of the lack of additional clinical data, when using ferric carboxymaltose, physicians/pharmacists should refer to the dilution and storing recommendations given in the product's summary of product characteristics. PMID:26835007

  12. Linkage and association of haplotypes at the APOA1/C3/A4/A5 genecluster to familial combined hyperlipidemia

    SciTech Connect

    Eichenbaum-Voline, Sophie; Olivier, Michael; Jones, Emma L.; Naoumova, Rossitza P.; Jones, Bethan; Gau, Brian; Seed, Mary; Betteridge,D. John; Galton, David J.; Rubin, Edward M.; Scott, James; Shoulders,Carol C.; Pennacchio, Len A.

    2002-09-15

    Combined hyperlipidemia (CHL) is a common disorder of lipidmetabolism that leads to an increased risk of cardiovascular disease. Thelipid profile of CHL is characterised by high levels of atherogeniclipoproteins and low levels of high-density-lipoprotein-cholesterol.Apolipoprotein (APO) A5 is a newly discovered gene involved in lipidmetabolism located within 30kbp of the APOA1/C3/A4 gene cluster. Previousstudies have indicated that sequence variants in this cluster areassociated with increased plasma lipid levels. To establish whethervariation at the APOA5 gene contributes to the transmission of CHL, weperformed linkage and linkage disequilibrium (LD) tests on a large cohortof families (n=128) with familial CHL (FCHL). The linkage data producedevidence for linkage of the APOA1/C3/A4/A5 genomic interval to FCHL (NPL= 1.7, P = 0.042). The LD studies substantiated these data. Twoindependent rare alleles, APOA5c.56G and APOC3c.386G of this gene clusterwere over-transmitted in FCHL (P = 0.004 and 0.007, respectively), andthis was associated with a reduced transmission of the most commonAPOA1/C3/A4/A5 haplotype (frequency 0.4425) to affected subjects (P =0.013). The APOA5c.56G allele was associated with increased plasmatriglyceride levels in FCHL probands, whereas the second, andindependent, APOC3c.386G allele was associated with increased plasmatriglyceride levels in FCHL pedigree founders. Thus, this allele (or anallele in LD) may mark a quantitative trait associated with FCHL, as wellas representing a disease susceptibility locus for the condition. Thisstudy establishes that sequence variation in the APOA1/C3/A4/A5 genecluster contributes to the transmission of FCHL in a substantialproportion of affected families, and that these sequence variants mayalso contribute to the lipid abnormalities of the metabolic syndrome,which is present in up to 40 percent of persons with cardiovasculardisease.

  13. 49 CFR 372.215 - Ravenswood, WV.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... foreign commerce, not under common control, management, or arrangement for a continuous carriage or... the limits of the combined areas defined in paragraphs (b) and (c) of this section, and (e) All of...

  14. 49 CFR 372.207 - Charleston, WV.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... foreign commerce, not under common control, management, or arrangement for a continuous carriage or... this section, and (e) All of any municipality wholly surrounded, or so surrounded except for a...

  15. The APOA1/C3/A4/A5 cluster and markers of allostatic load in the Boston Puerto Rican Health Study

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The APOA1/C3/A4/A5 cluster encodes key regulators of plasma lipids. Interactions between dietary factors and single nucleotide polymorphisms (SNPs) in the cluster have been reported. Allostatic load, or physiological dysregulation in response to stress, has been implicated in shaping health disparit...

  16. Effects of variations in the APOA1/C3/A4/A5 gene cluster on different parameters of postprandial lipid metabolism in healthy young men.

    PubMed

    Delgado-Lista, Javier; Perez-Jimenez, Francisco; Ruano, Juan; Perez-Martinez, Pablo; Fuentes, Francisco; Criado-Garcia, Juan; Parnell, Laurence D; Garcia-Rios, Antonio; Ordovas, Jose M; Lopez-Miranda, Jose

    2010-01-01

    The APOA1/C3/A4/A5 gene cluster encodes important regulators of fasting lipids, but the majority of lipid metabolism takes place in the postprandial state and knowledge about gene regulation in this state is scarce. With the aim of characterizing possible regulators of lipid metabolism, we studied the effects of nine single nucleotide polymorphisms (SNPs) during postprandial lipid metabolism. Eighty-eight healthy young men were genotyped for APOA1 -2630 (rs613808), APOA1 -2803 (rs2727784), APOA1 -3012 (rs11216158), APOC3 -640 (rs2542052), APOC3 -2886 (rs2542051), APOC3 G34G (rs4520), APOA4 N147S (rs5104), APOA4 T29T (rs5092), and A4A5_inter (rs1263177) and were fed a saturated fatty acid-rich meal (1g fat/kg of weight with 60% fat, 15% protein and 25% carbohydrate). Serial blood samples were extracted for 11 h after the meal. Total cholesterol and fractions [HDL-cholesterol, LDL-cholesterol, trifacylglycerols (TGs) in plasma, TG-rich lipoproteins (TRLs) (large TRLs and small TRLs), apolipoprotein A-I and apolipoprotein B] were determined. APOA1 -2803 homozygotes for the minor allele and A4A5_inter carriers showed a limited degree of postprandial lipemia. Carriers of the rare alleles of APOA4 N147S and APOA4 T29T had lower APOA1 plasma concentration during this state. APOC3 -640 was associated with altered TG kinetics but not its magnitude. We have identified new associations between SNPs in the APOA1/C3/A4/A5 gene cluster and altered postprandial lipid metabolism.

  17. 77 FR 65248 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-25

    ... Bureau of the Public Debt Proposed Collection: Comment Request ACTION: Notice and request for comments... 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the Bureau of the Public Debt within the... written comments to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg,...

  18. 77 FR 74053 - Proposed Collection: Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-12

    ... Bureau of the Public Debt Proposed Collection: Comment Request ACTION: Notice and request for comments... 1995, Public Law 104-13 (44 U.S.C. 3506(c)(2)(A). Currently the Bureau of the Public Debt within the... written comments to Bureau of the Public Debt, Bruce A. Sharp, 200 Third Street A4-A, Parkersburg,...

  19. Haplotypes in the APOA1-C3-A4-A5 gene cluster affect plasma lipids in both humans and baboons.

    PubMed

    Wang, Qian-fei; Liu, Xin; O'Connell, Jeff; Peng, Ze; Krauss, Ronald M; Rainwater, David L; VandeBerg, John L; Rubin, Edward M; Cheng, Jan-Fang; Pennacchio, Len A

    2004-05-15

    Genetic studies in non-human primates serve as a potential strategy for identifying genomic intervals where polymorphisms impact upon human disease-related phenotypes. It remains unclear, however, whether independently arising polymorphisms in orthologous regions of non-human primates leads to similar variation in a quantitative trait found in both species. To explore this paradigm, we studied a baboon apolipoprotein gene cluster (APOA1/C3/A4/A5) for which the human gene orthologs have well-established roles in influencing plasma HDL-cholesterol and triglyceride concentrations. Our extensive polymorphism analysis of this 68 kb gene cluster in 96 pedigreed baboons identified several haplotype blocks each with limited diversity, consistent with haplotype findings in humans. To determine whether baboons, like humans, also have particular haplotypes associated with lipid phenotypes, we genotyped 634 well-characterized baboons using 16 haplotype tagging SNPs. Genetic analysis of single SNPs, as well as haplotypes, revealed an association of APOA5 and APOC3 variants with HDL-cholesterol and triglyceride concentrations, respectively. Thus, independent variation in orthologous genomic intervals does associate with similar quantitative lipid traits in both species, supporting the possibility of uncovering human quantitative trait loci genes in a highly controlled non-human primate model.

  20. Haplotypes in the APOA1-C3-A4-A5 gene cluster affect plasma lipids in both humans and baboons

    SciTech Connect

    Wang, Qian-fei; Liu, Xin; O'Connell, Jeff; Peng, Ze; Krauss, Ronald M.; Rainwater, David L.; VandeBerg, John L.; Rubin, Edward M.; Cheng, Jan-Fang; Pennacchio, Len A.

    2003-09-15

    Genetic studies in non-human primates serve as a potential strategy for identifying genomic intervals where polymorphisms impact upon human disease-related phenotypes. It remains unclear, however, whether independently arising polymorphisms in orthologous regions of non-human primates leads to similar variation in a quantitative trait found in both species. To explore this paradigm, we studied a baboon apolipoprotein gene cluster (APOA1/C3/A4/A5) for which the human gene orthologs have well established roles in influencing plasma HDL-cholesterol and triglyceride concentrations. Our extensive polymorphism analysis of this 68 kb gene cluster in 96 pedigreed baboons identified several haplotype blocks each with limited diversity, consistent with haplotype findings in humans. To determine whether baboons, like humans, also have particular haplotypes associated with lipid phenotypes, we genotyped 634 well characterized baboons using 16 haplotype tagging SNPs. Genetic analysis of single SNPs, as well as haplotypes, revealed an association of APOA5 and APOC3 variants with HDL cholesterol and triglyceride concentrations, respectively. Thus, independent variation in orthologous genomic intervals does associate with similar quantitative lipid traits in both species, supporting the possibility of uncovering human QTL genes in a highly controlled non-human primate model.

  1. 76 FR 57013 - Approval and Promulgation of Air Quality Implementation Plans; West Virginia; Revised Motor...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-15

    ...; Revised Motor Vehicle Emission Budgets for the Charleston, Huntington, Parkersburg, Weirton, and Wheeling..., Huntington, Parkersburg, Weirton, and Wheeling 8-hour ozone maintenance areas. This revision amends...

  2. Sputtering Deposition of Sandwich-Structured V2O5/Metal (V, W)/V2O5 Multilayers for the Preparation of High-Performance Thermally Sensitive VO2 Thin Films with Selectivity of VO2 (B) and VO2 (M) Polymorph.

    PubMed

    Liu, Hengwu; Wan, Dongyun; Ishaq, Ahmad; Chen, Lanli; Guo, Beibei; Shi, Siqi; Luo, Hongjie; Gao, Yanfeng

    2016-03-01

    For specific application to an uncooled infrared detector, VO2 thin films should have a series of characteristics including purposefully chosen polymorphs, accurate stoichiometry, phase stabilization, a high temperature-coefficient of resistance (TCR), and suitable square-resistance. This work reports controllable preparation of high-performance VO2 films via post annealing of a sandwich-structured V2O5/metal (V, W)/V2O5 multilayer precursor, which was deposited by RF magnetron sputtering. This sandwich structure can dynamically regulate oxygen contents and doping element levels in the films, enabling us to achieve accurate regulation of stoichiometry and polymorphs. The precursor films undergo a B to M phase transition depending on the quantity of the metal layers. At the thickness of the metal layer below a limitation, the resulting film after heat treatment was VO2 (B), and above the limitation, the product was VO2 (M). The optical modulation of the VO2 (M) in the near-infrared region can be tuned from 1.2 to 39.8% (ΔT2000 nm). TCR values can range from -1.89 to -4.29%/K and the square-resistances at room temperature (R0) from 69.68 to 12.63 kΩ. The simplicity in phase regulation of the present method and the superior optical and electrical properties of the films may allow its wide applications in thermo-opto-electro sensing devices.

  3. 76 FR 28312 - Safety Zones; Fireworks Display Kanawha River, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ... Federal Register (73 FR 3316). Public Meeting We do not now plan to hold a public meeting. But you may... publicity among the affected segments of the public. Discussion of Rule The Captain of the Port Ohio...

  4. 77 FR 3836 - Supplemental Environmental Impact Statement, Mingo County, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-25

    ... portion of the King Coal Highway 2000 FEIS and the Buffalo Mountain Surface Mine Clean Water Act Section... USACE is evaluating a Clean Water Act (CWA) Section 404 Individual Permit (IP) application submitted by....S.) in conjunction with the construction and operation of the Buffalo Mountain Surface Mine....

  5. Argus Energy WV, LLC wins 2007 Wetlands West Virginia Award

    SciTech Connect

    2007-07-15

    Argus Energy's Kiah Creek Operation has received the 2007 Wetlands West Virginia Award presented by the West Virginian Coal Association. The operation was originally a 1267 acre underground mine in the Coalburg seam. Underground mining commenced in 2000 until the end of 2003 with more than two million tons of coal being produced. The creation of the wetlands was achieved during the operations. 8 photos.

  6. Nobody Asked Us: The WV Welfare Reform Listening Project.

    ERIC Educational Resources Information Center

    Wilson, Rick

    West Virginia's state welfare reform plan was in effect by the end of 1997. In 1999, over 175 interviews were conducted with past and present welfare recipients to bring their experiences and concerns to the attention of the public and policymakers. Nearly all interviewees were women and were taking part in work activities. In general, welfare…

  7. 76 FR 34606 - Special Local Regulation; Monongahela River, Morgantown, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-14

    ... regulation is being established to safeguard participants of the Mountaineer Triathlon from the hazards of... safeguard participants during the Mountaineer Triathlon marine event from the hazards imposed by marine... needed to provide safety and protection during the Mountaineer Triathlon marine event that will occur...

  8. Development of a new fluorescent probe: 1,3,5,7-tetramethyl-8-(4'-aminophenyl)-4,4-difluoro-4-bora-3a,4a-diaza-s-indacence for the determination of trace nitrite.

    PubMed

    Li, Mengling; Wang, Hong; Zhang, Xian; Zhang, Hua-Shan

    2004-03-01

    A new fluorescent probe, 1,3,5,7-tetramethyl-8-(4'-aminophenyl)-4,4-difluoro-4-bora-3a,4a-diaza-s-indacence (TMABODIPY) has been developed for the determination of trace nitrite in terms of the reaction of nitrite with TMABODIPY first in acidic solution and then in alkaline solution to form diazotate, a stable and highly fluorescent reagent. The method offered the advantage of specificity, sensitivity and simplicity. The linear calibration range for nitrite was 8-300 nmol l-1s with a 3 sigma detection limit of 0.65 nmol l-1. The proposed method has been applied to monitor the trace nitrite in drinking water and vegetable without extraction.

  9. Sampling and analysis of selected toxic substances. Task 1: polybrominated biphenyls in air and soil at user sites. Final report 28 dec 78-5 jun 79

    SciTech Connect

    Zweidinger, R.A.; Pellizzari, E.D.

    1980-02-01

    Field sampling for air and soil was conducted in the vicinity of two Borg Warner Co. facilities - one in Oxnard, CA and the other near Parkersburg, WV. Polybrominated biphenyls (PBBs) were found in all of the soil samples from Oxnard with the highest levels (36,000 microgram/kg) nearest the facility and the lowest (5 microgram/kg) upwind the greatest distance. No PBBs were found in any of the air samples (<3 ng/cu m). Polybrominated biphenyls were confirmed in seven of the thirteen soil samples from West Virginia (up to 12 microgram/kg) traces detected but not confirmed in three, and no PBBs were detected in the other three. The highest levels were from samples collected in the Ohio River basin especially along the eastern bank. No PBBs were confirmed in the air samples (<4 ng/cu m).

  10. Vapor hydration and subsequent leaching of transuranic-containing SRL and WV glasses

    SciTech Connect

    Bates, J.K.; Ebert, W.L.; Gerding, T.J.

    1989-09-01

    Prior to contact by liquid water and subsequent leaching, high-level nuclear waste glass subject to disposal in the unsaturated environment at Yucca Mountain, Nevada, will be altered through contact with humid air. Conditions could range from temperatures as high as 200{degree}C to ambient repository temperature after cooling and relative humidities up to 100% depending on the air flow and heat transport dynamics of the waste package and near field environments. However, under any potential set of temperature/humidity conditions, the glass will undergo alteration via well-established vapor phase hydration processes. In the present paper, the results of a set of parametric experiments are described, whereby vapor phase hydrated glasses were subjected to leaching under static conditions. The purpose of the experiments was to (1) compare the leaching of vapor phase altered glass to that of fresh glass, (2) to develop techniques for determining the radionuclide content of secondary phases that formed during the hydration reaction, and (3) to provide a basis for performing long-term saturated and unsaturated testing of vapor hydrated glass. 3 refs., 2 figs., 2 tabs.

  11. 76 FR 64295 - Proposed Amendment of Class E Airspace; Huntington, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-18

    ...; (2) is not a ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February... read as follows: Authority: 49 U.S.C. 106(g); 40103, 40113, 40120; E.O. 10854, 24 FR 9565, 3 CFR, 1959... Federal Aviation Administration 14 CFR Part 71 Proposed Amendment of Class E Airspace; Huntington,...

  12. Cometary radio astronomy; Proceedings of the NRAO Workshop, Green Bank, WV, Sept. 24-26, 1986

    SciTech Connect

    Irvine, W.M.; Schloerb, F.P.; Tacconi-Garman, L.E.

    1987-01-01

    Papers are presented on the cometary plasma, near-nucleus observations of P/Halley, scintillations of four radio sources occulted by the plasma tail of Comet Halley, and modeling of the excitation of molecules at radio wavelengths and the thermodynamics of the coma. Also considered are observations of HCN in Comet Halley, the search for parent molecules, the search for molecules in Comet Halley at millimeter wavelengths, and the OH radio lines in comets. Other topics include OH radio observations of Comet Halley from the Southern Hemisphere, radio OH observations of P/Halley with the NRAO 43-m telescope, models of the OH 18-cm line profiles of Comet Halley, and the first radio images of OH emission from Comet Halley.

  13. 75 FR 55612 - TRG Insurance Solutions, LLC; Beckley, WV; Notice of Affirmative Determination Regarding...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-13

    ..., 2010. The Notice of Determination was published in the Federal Register on August 2, 2010 (75 FR 45164). Workers are engaged in employment related to the supply of insurance call center services. The negative..., shift to/ acquire from a foreign country services like or directly competitive with the insurance...

  14. 75 FR 65525 - TRG Insurance Solutions, Beckley, WV; Notice of Revised Determination on Reconsideration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-25

    ...). Workers at the subject firm are engaged in employment related to the supply of insurance call center... or directly competitive with the insurance call center services supplied by the subject workers... related to the supply of insurance call center services, meet the worker group certification...

  15. 75 FR 65251 - Proposed Amendment of Class E Airspace; Charleston, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-22

    ... airspace needed for the holding pattern associated with the new Standard Instrument Approach Procedures (SIAPs) developed at Yeager Airport. This action would enhance the safety and airspace management of... Operations, West Building Ground Floor, Room W12-140, 1200 New Jersey Avenue, SE., Washington, DC...

  16. 76 FR 12365 - Canaan Valley National Wildlife Refuge, Tucker and Grant Counties, WV; Final Comprehensive...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-07

    ... 15 years. ADDRESSES: You may view or obtain copies of the final CCP and FONSI by any of the following... administering Canaan Valley NWR for the next 15 years. Alternative B, as we described in the draft CCP/EA, is... developing a CCP is to provide refuge managers with a 15-year plan for achieving refuge purposes...

  17. 70 FR 8640 - ITW Insulation Systems, Nitro, WV; Notice of Negative Determination on Reconsideration

    Federal Register 2010, 2011, 2012, 2013, 2014

    2005-02-22

    ... Register on January 21, 2005 (70 FR 3227). The petition for the workers of ITW Insulation Systems, Nitro, West Virginia engaged in production of metal jacketing and industrial thermal insulation applications... metal jacketing an industrial thermal insulation applications during the relevant period. The...

  18. WV R-EMAP STUDY: MULTIPLE-OBJECTIVE SAMPLING DESIGN FRAMEWORK

    EPA Science Inventory

    A multi-objective sampling design has been implemented through Regional Monitoring and Assessment Program (R-EMAP) support of a cooperative agreement with the state of West Virginia. Goals of the project include: 1) development and testing of a temperature-adjusted fish IBI for t...

  19. 78 FR 8589 - Verizon Services Corporation, Customer Services Clerk, General Clerk, Clarksburg, WV; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-06

    ... Employment and Training Administration Verizon Services Corporation, Customer Services Clerk, General Clerk... of Verizon Services Corporation, Customer Services Clerk, General Clerk, Clarksburg, West Virginia... determination was published in the Federal Register on January 10, 2013 (78 FR 2290). The initial...

  20. 75 FR 63540 - Request for Public Comment, Morgantown Municipal Airport, Morgantown, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... Sponsor's operation and development of the Morgantown Airport. Once released, the land will change to a... land currently owned by the City of Morgantown, Sponsor for the Morgantown Municipal Airport... property. The land is currently being used as a cross wind runway. It has been determined that this...

  1. 77 FR 55899 - CSX Transportation, Inc.-Discontinuance of Service Exemption-in Raleigh County, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-11

    ... approximately 13.5 miles of rail line between milepost WG 12.0 near Helen and milepost WG 25.5 at McVey in Raleigh County, W. Va. The line is owned by Norfolk Southern Railway Company (NSR) and has been operated...--Norfolk & W. Ry., FD 32768 (ICC served Oct. 27, 1995). According to CSXT, the lease was amended in...

  2. Use of fluorescence-activated flow cytometry to determine membrane lipid peroxidation during hypothermic liquid storage and freeze-thawing of viable boar sperm loaded with 4, 4-difluoro-5-(4-phenyl-1,3-butadienyl)-4-bora-3a,4a-diaza-s-indacene-3-undecanoic acid.

    PubMed

    Guthrie, H D; Welch, G R

    2007-06-01

    Part of the reduction in boar sperm motility and fertility associated with hypothermic liquid storage and cryopreservation may be due to membrane lipid peroxidation. Lipid peroxidation was monitored by the shift from red to green fluorescence emission of the lipophilic probe 4, 4-difluoro-5-(4-phenyl-1,3-butadienyl)-4-bora-3a,4a-diaza-s-indacene-3-undecanoic acid, C(11)BODIPY(581/591) (BODIPY), as measured by fluorescence-activated flow cytometry in live sperm (negative for propidium iodide). Experiments were conducted with Percoll-washed sperm to determine the specificity of BODIPY oxidation in the presence of different reactive oxygen species generators and metal chelators. Compared with no FeSO(4) and Na ascorbate, the combination of FeSO(4) and Na ascorbate (FeAc) increased (P < 0.01) the percentage of sperm containing oxidized BODIPY from 70% and increased (P < 0.05) BOD-IPY fluorescence intensity/cell by 5- to 10-fold after a 30-min incubation. Motility was depressed (P < 0.05) after exposure to FeAc, but viability was not affected. Of the reactive oxygen species generators tested, BODIPY oxidation was specific for FeAc, because menadione and H(2)O(2) had little or no effect. The oxidization of hydroethidine to ethidium was specific for menadione and H(2)O(2); FeAc had no effect. The presence of the metal chelators EDTA or deferoxamine mesylate at 3 and 9 muM inhibited FeAc-induced BODIPY oxidation and maintained motility. Experiments were conducted to determine the effect of liquid storage at 17 degrees C for 1 and 5 d and the effect of freeze-thawing on basal and FeAc-induced BODIPY oxidation. Basal BODIPY oxidation (no FeAc) was low in liquid stored and thawed viable sperm (1.3 and 3.4%, respectively). Although the incidence of basal or spontaneous membrane lipid peroxidation was low during liquid storage and after freeze-thawing, viable boar sperm were susceptible to FeAc-induced lipid peroxidation. PMID:17296775

  3. Superfund record of decision (EPA Region 3): Allegany Ballistics Laboratory (USNavy) Site 10, Mineral, WV, June 30, 1998

    SciTech Connect

    1998-12-01

    This decision document presents the selected remedial action for Site 10 (the Site) Groundwater at the Allegany Ballistics Laboratory (ABL), Rocket Center, West Virginia. The major components of the selected remedy are: Institutional controls, including land use restrictions imposed through appropriate administrative mechanisms to prevent groundwater use; Groundwater pumping from a minimum of three extraction wells to capture the hot spot of the VOC contaminant plume; Installation of a pipeline to transport groundwater from Site 10 to the Site 1 treatment plant; Discharge to the North Branch Potomac River; and Groundwater monitoring on a timely basis, quarterly to semi-annually, will evaluate groundwater quality, contaminant migration, and degradation for inclusion in the 5-year site reviews.

  4. Superfund Record of Decision (EPA Region 3): Allegany Ballistics Laboratory (USNavy), Operable Unit 1, Mineral, WV, February 12, 1997

    SciTech Connect

    1998-01-01

    This decision document presents the selected remedial action for Site 5 Landfill Contents and Surface Soil at the Allegany Ballistics Laboratory (ABL), Rocket Center, West Virginia. The major components of the selected remedy are: Deed notation along with property use and limited access restrictions; Installation of a composite CAP-GCL and FMC; Installation of a drainage layer utilizing a geonet; Installation of a passive landfill gas (LFG) venting system; Revegetation of the capped area; Installation of perimeter drainage system; and Post-closure requirements.

  5. 75 FR 1806 - Draft General Management Plan and Environmental Impact Statement, New River Gorge National River, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-13

    ... with National Park Service laws, regulations, and policies, and the purpose of the National River, the...; floodplains; water quality; vegetation; aquatic wildlife; terrestrial wildlife; rare, threatened, and... signed into law in 1978, including several boundary changes. The most recent legislation mandates...

  6. Feasibility study of wood-fired cogeneration at a Wood Products Industrial Park, Belington, WV. Phase II

    SciTech Connect

    Vasenda, S.K.; Hassler, C.C.

    1992-06-01

    Customarily, electricity is generated in a utility power plant while thermal energy is generated in a heating/cooling plant; the electricity produced at the power plant is transmitted to the heating/cooling plant to power equipments. These two separate systems waste vast amounts of heat and result in individual efficiencies of about 35%. Cogeneration is the sequential production of power (electrical or mechanical) and thermal energy (process steam, hot/chilled water) from a single power source; the reject heat of one process issued as input into the subsequent process. Cogeneration increases the efficiency of these stand-alone systems by producing these two products sequentially at one location using a small additional amount of fuel, rendering the system efficiency greater than 70%. This report discusses cogeneration technologies as applied to wood fuel fired system.

  7. 75 FR 47715 - Safety Zone; Kanawha River Mile 56.7 to 57.6, Charleston, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-09

    ... Governor's Cup Jet Ski Race. Entry into this zone is prohibited unless specifically authorized by the... Purpose The Upstate Watercraft Promotions, Inc. is sponsoring a jet ski race from 12 p.m. to 6 p.m. on... vicinity of the jet ski race. A safety zone is needed to protect those vessels, mariners and...

  8. 78 FR 72881 - Adequacy Status of the West Virginia Portion of the Steubenville-Weirton, WV-OH Nonattainment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-04

    ... directly emitted fine particulate matter (PM 2.5 ) and nitrogen oxides (NO X ) in the West Virginia portion... process for determining the adequacy of submitted SIP budgets in a July 1, 2004 preamble starting at 69...

  9. 78 FR 72880 - Adequacy Status of the West Virginia Portion of the Steubenville-Weirton, WV-OH Nonattainment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-04

    ... directly emitted fine particulate matter (PM 2.5 ) and nitrogen oxides (NO X ) in the West Virginia portion... process for determining the adequacy of submitted SIP budgets in a July 1, 2004 preamble starting at 69...

  10. 77 FR 60087 - Approval and Promulgation of Air Quality Implementation Plans; West Virginia; The 2002 Base Year...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-02

    ... 2002 Base Year Inventory for the Parkersburg Area AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule. SUMMARY: EPA is proposing to approve the fine particulate matter (PM 2.5 ) 2002 base year... approve the 2002 base year PM 2.5 emissions inventory for the Parkersburg Area in accordance with...

  11. Increased expression of S100A4, a metastasis-associated gene, in human colorectal adenocarcinomas.

    PubMed

    Takenaga, K; Nakanishi, H; Wada, K; Suzuki, M; Matsuzaki, O; Matsuura, A; Endo, H

    1997-12-01

    The S100A4 gene (also known as pEL98/mts1/p9Ka/18A2/42A/calvasculin /FSP1/CAPL) encoding an S100-related calcium-binding protein is implied to be involved in the invasion and metastasis of murine tumor cells. In the present study, the expression of S100A4 in human colorectal adenocarcinoma cell lines (SW837, LoVo, DLD-1, HT-29, SW480, SW620, WiDr, and Colo201) and surgically resected neoplastic tissues was examined to investigate whether S100A4 plays a role in the invasion and metastasis of human tumor cells. Northern blot analysis using total RNA isolated from the adenocarcinoma cell lines revealed that five of the eight cell lines expressed substantial amounts of S100A4 mRNA. Normal colon fibroblasts (CCD-18Co) expressed little of the RNA. Using surgically resected specimens, it seemed that the amount of S100A4 mRNA in adenomas was nearly equal to that in normal colonic mucosa, whereas adenocarcinomas expressed a significantly higher amount of the RNA than did the adjacent normal colonic mucosa. Immunohistochemical analysis using formalin-fixed paraffin-embedded surgical specimens and monoclonal anti-S100A4 antibody demonstrated that none of 12 adenoma specimens were immunopositive, whereas 8 of 18 (44%) focal carcinomas in carcinoma in adenoma specimens and 50 of 53 (94%) adenocarcinoma specimens were immunopositive. Interestingly, the incidence of immunopositive cells increased according to the depth of invasion, and nearly all of the carcinoma cells in 14 metastases in the liver were positive. These results suggest that S100A4 may be involved in the progression and the metastatic process of human colorectal neoplastic cells. PMID:9815629

  12. 31 CFR 351.2 - How do I contact Fiscal Service?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Service by e-mail at savbonds@bpd.treas.gov, or by writing to the following address: Bureau of the Fiscal Service, Parkersburg, West Virginia 26106-1328. Our website address is www.savingsbonds.gov....

  13. 75 FR 82146 - Prompt Payment Interest Rate; Contract Disputes Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-29

    ...: Comments or inquiries may be mailed to Dorothy Dicks, Reporting Team Leader, Federal Borrowings Branch..., Parkersburg, West Virginia 26106-1328, (304) 480-5103; Dorothy Dicks, Reporting Team Leader,...

  14. 76 FR 38742 - Prompt Payment Interest Rate; Contract Disputes Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-01

    ..., 2011, to December 31, 2011. ADDRESSES: Comments or inquiries may be mailed to Dorothy Dicks, Reporting..., Parkersburg, West Virginia 26106-1328, (304) 480-5103; Dorothy Dicks, Reporting Team Leader,...

  15. RETROFIT COSTS FOR SO2 AND NOX CONTROL OPTIONS AT 200 COAL-FIRED PLANTS, VOLUME V - SITE SPECIFIC STUDIES FOR PA, SC, TN, VA, WI, WV

    EPA Science Inventory

    The report gives results of a study, the objective of which was to significantly improve engineering cost estimates currently being used to evaluate the economic effects of applying SO2 and NOx controls at 200 large SO2-emitting coal-fired utility plants. To accomplish the object...

  16. Structural anisotropy of cyanido-bridged {CoII9WV6} single-molecule magnets induced by bidentate ligands: towards the rational enhancement of an energy barrier.

    PubMed

    Chorazy, Szymon; Rams, Michał; Hoczek, Anna; Czarnecki, Bernard; Sieklucka, Barbara; Ohkoshi, Shin-ichi; Podgajny, Robert

    2016-04-01

    Pentadecanuclear {CII9[W(V)(CN)8]6} clusters were combined with bidentate 2,2'-bipyridine N,N'-dioxide (2,2'-bpdo) ligands resulting in two distinct molecules, {Co9W6(2,2'-bpdo)7} (cluster A) and {Co9W6(2,2'-bpdo)6} (cluster B), capped by seven and six 2,2'-bpdo ligands, respectively. They crystallize within a single {Co9W6(2,2'-bpdo)7}·{Co9W6(2,2'-bpdo)6}·solvent (1) supramolecular network, and reveal single-molecule magnet behaviour with an enhanced energy barrier, a ΔE/kB of 30.0(8) K, which was tentatively ascribed to seven-capped axially deformed cluster A. PMID:26933695

  17. Preparation and characterization of chloramphenicol niosomes and comparison with chloramphenicol eye drops (0.5%w/v) in experimental conjunctivitis in albino rabbits.

    PubMed

    Yasin, Muhammad Naveed; Hussain, Shahzad; Malik, Farnaz; Hameed, Abdul; Sultan, Tipu; Qureshi, Fahim; Riaz, Humayun; Perveen, Ghazala; Wajid, Amina

    2012-01-01

    Niosomes has gained tremendous popularity as ultimate drug carrier. Lot of research work is being carried out on preparation of niosomes for ophthalmic use having no significant effect on vision and its sustained release pattern. Chloramphenicol niosomes were prepared using two different ratios of cholesterol, drug and surfactant, termed as EIN-1, EIN-2 by ether injection method and their entrapment efficiency, particle size. The in vitro drug release pattern was observed for ten hours. The EIN-2 showed 90% entrapment and released 81% of entrapped drug after 10 hours. Zeta potential & viscosity were determined and in-vivo comparison was made with Chloramphenicol eye drops where it exhibited Cmax of 15 μ g/ml. Stability studies were done to determine shelf life. MIC of selected strain of S. aureus was also determined. EIN 2 niosomal suspension was compared with Chloramphenicol eye drops in experimental conjunctivitis in albino rabbits. In-vitro studies are encouraging as niosomes released about 75% of total entrapped drug by EIN-1 and 81% of total entrapped drug by EIN 2. In vivo study shows that niosomes released the drug in eye in acceptable range and showed a sustained release pattern without affecting the vision. Niosomes were found ultimate ophthalmic drug carriers capable to release drug in sustained and determined pattern.

  18. Category and Perceptual Interference in Second-Language Phoneme Learning: An Examination of English /w/-/v/ Learning by Sinhala, German, and Dutch Speakers

    ERIC Educational Resources Information Center

    Iverson, Paul; Ekanayake, Dulika; Hamann, Silke; Sennema, Anke; Evans, Bronwen G.

    2008-01-01

    The present study investigated the perception and production of English /w/ and /v/ by native speakers of Sinhala, German, and Dutch, with the aim of examining how their native language phonetic processing affected the acquisition of these phonemes. Subjects performed a battery of tests that assessed their identification accuracy for natural…

  19. An application for impedance spectroscopy in the characterisation of the glass transition during the lyophilization cycle: the example of a 10% w/v maltodextrin solution.

    PubMed

    Smith, Geoff; Arshad, Muhammad Sohail; Polygalov, Eugene; Ermolina, Irina

    2013-11-01

    Impedance spectroscopy has been used for the measurement of the glass transition of a 10 % maltodextrin solution contained within a glass vial, with externally attached electrodes. Features of the pseudo-relaxation process, associated with the composite impedance of the glass vial-solution assembly, were characterised by the peak amplitude, C(peak)(″), and peak frequency, f(peak), of the capacitance spectra and the equivalent circuit elements that model the impedance spectra (i.e. the solution resistance and solution capacitance) and monitored every 3 min during re-heating of the solution. The time derivatives of all four parameters studied provided a glass transition in close agreement with DSC measurements (-17 °C) and at a precision of ± 0.5 °C. The temperature dependencies of the solution resistance and peak frequency were then characterised with the Arrhenius and Vogel-Fulcher-Tammann fit functions, at temperatures below and above Tg, respectively. The energy of activation (below Tg) was estimated at ~20 kJ mol(-1), and the fragility index (If) of the glass forming liquid (above Tg) was estimated at 0.9. The significance of the fragility index to the development, optimisation and control of the freeze-drying cycle is highlighted.

  20. A Watershed-based spatially-explicit demonstration of an Integrated Environmental Modeling Framework for Ecosystem Services in the Coal River Basin (WV, USA)

    EPA Science Inventory

    We demonstrate a spatially-explicit regional assessment of current condition of aquatic ecoservices in the Coal River Basin (CRB), with limited sensitivity analysis for the atmospheric contaminant mercury. The integrated modeling framework (IMF) forecasts water quality and quant...

  1. 26 CFR 1.170A-4A - Special rule for the deduction of certain charitable contributions of inventory and other property.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES... property, the amount of the deduction is accordingly further reduced under paragraph (c)(1) of this section... donor's deduction is reduced to the amount allowable under section 170 of the regulations...

  2. 26 CFR 1.170A-4A - Special rule for the deduction of certain charitable contributions of inventory and other property.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... language, cultural, or financial difficulties, a minor child who is not self-sufficient and who is not... contribution is reduced a second time to an amount which is equal to twice the amount of the basis of the... contribution which may be taken into account is $600 ($1,000−$400). A second reduction is made in the amount...

  3. Draft Genome Sequence of Pantoea sp. Strain A4, a Rafflesia-Associated Bacterium That Produces N-Acylhomoserine Lactones as Quorum-Sensing Molecules

    PubMed Central

    Hong, Kar-Wai; Gan, Han Ming; Low, Siew-Moon; Lee, Patrick Kok Yuen; Chong, Yee-Meng; Yin, Wai-Fong

    2012-01-01

    Pantoea sp. strain A4 is a Gram-negative bacterium isolated from the Rafflesia flower. We present here, for the first time, the genome sequence of Rafflesia-associated Pantoea sp. strain A4, which exhibited quorum-sensing activity. PMID:23144374

  4. 26 CFR 1.170A-4A - Special rule for the deduction of certain charitable contributions of inventory and other property.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... under this section which is subject to the Federal Food, Drug, and Cosmetic Act (as amended), and.... Under paragraph (b)(2) of this section, the use of the property must be related to the purpose or.... Also, the property must be used for the care of the ill, needy, or infants. Under paragraph (b)(3)...

  5. 26 CFR 1.170A-4A - Special rule for the deduction of certain charitable contributions of inventory and other property.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... under this section which is subject to the Federal Food, Drug, and Cosmetic Act (as amended), and.... Under paragraph (b)(2) of this section, the use of the property must be related to the purpose or.... Also, the property must be used for the care of the ill, needy, or infants. Under paragraph (b)(3)...

  6. 26 CFR 1.170A-4A - Special rule for the deduction of certain charitable contributions of inventory and other property.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... under this section which is subject to the Federal Food, Drug, and Cosmetic Act (as amended), and.... Under paragraph (b)(2) of this section, the use of the property must be related to the purpose or.... Also, the property must be used for the care of the ill, needy, or infants. Under paragraph (b)(3)...

  7. The Effect of microRNAs in the Regulation of Human CYP3A4: a Systematic Study using a Mathematical Model

    NASA Astrophysics Data System (ADS)

    Wei, Zhiyun; Jiang, Songshan; Zhang, Yiting; Wang, Xiaofei; Peng, Xueling; Meng, Chunjie; Liu, Yichen; Wang, Honglian; Guo, Luo; Qin, Shengying; He, Lin; Shao, Fengmin; Zhang, Lirong; Xing, Qinghe

    2014-03-01

    CYP3A4 metabolizes more than 50% of the drugs on the market. The large inter-individual differences of CYP3A4 expression may contribute to the variability of human drug responses. Post-transcriptional regulation of CYP3A4 is poorly understood, whereas transcriptional regulation has been studied much more thoroughly. In this study, we used multiple software programs to predict miRNAs that might bind to CYP3A4 and identified 112 potentially functional miRNAs. Then a luciferase reporter system was used to assess the effect of the overexpression of each potentially functional miRNA in HEK 293T cells. Fourteen miRNAs that significantly decreased reporter activity were measured in human liver samples (N = 27) as candidate miRNAs. To establish a more effective way to analyze in vivo data for miRNA candidates, the relationship between functional miRNA and target mRNA was modeled mathematically. Taking advantage of this model, we found that hsa-miR-577, hsa-miR-1, hsa-miR-532-3p and hsa-miR-627 could significantly downregulate the translation efficiency of CYP3A4 mRNA in liver. This study used in silico, in vitro and in vivo methods to progressively screen functional miRNAs for CYP3A4 and to enhance our understanding of molecular events underlying the large inter-individual differences of CYP3A4 expression in human populations.

  8. NBCe1 (SLC4A4) a potential pH regulator in enamel organ cells during enamel development in the mouse.

    PubMed

    Jalali, R; Guo, J; Zandieh-Doulabi, B; Bervoets, T J M; Paine, M L; Boron, W F; Parker, M D; Bijvelds, M J C; Medina, J F; DenBesten, P K; Bronckers, A L J J

    2014-11-01

    During the formation of dental enamel, maturation-stage ameloblasts express ion-transporting transmembrane proteins. The SLC4 family of ion-transporters regulates intra- and extracellular pH in eukaryotic cells by cotransporting HCO3 (-) with Na(+). Mutation in SLC4A4 (coding for the sodium-bicarbonate cotransporter NBCe1) induces developmental defects in human and murine enamel. We have hypothesized that NBCe1 in dental epithelium is engaged in neutralizing protons released during crystal formation in the enamel space. We immunolocalized NBCe1 protein in wild-type dental epithelium and examined the effect of the NBCe1-null mutation on enamel formation in mice. Ameloblasts expressed gene transcripts for NBCe1 isoforms B/D/C/E. In wild-type mice, weak to moderate immunostaining for NBCe1 with antibodies that recognized isoforms A/B/D/E and isoform C was seen in ameloblasts at the secretory stage, with no or low staining in the early maturation stage but moderate to high staining in the late maturation stage. The papillary layer showed the opposite pattern being immunostained prominently at the early maturation stage but with gradually less staining at the mid- and late maturation stages. In NBCe1 (-/-) mice, the ameloblasts were disorganized, the enamel being thin and severely hypomineralized. Enamel organs of CFTR (-/-) and AE2a,b (-/-) mice (CFTR and AE2 are believed to be pH regulators in ameloblasts) contained higher levels of NBCe1 protein than wild-type mice. Thus, the expression of NBCe1 in ameloblasts and the papillary layer cell depends on the developmental stage and possibly responds to pH changes.

  9. Stable paramagnetic half-sandwich Mo(V) and W(V) polyhydride complexes. Structural, spectroscopic, electrochemical, theoretical, and decomposition mechanism studies of [Cp*MH{sub 3}(dppe)]{sup +} (M = Mo, W)

    SciTech Connect

    Pleune, B.; Morales, D.; Meunier-Prest, R.; Richard, P.; Collange, E.; Fettinger, J.C.; Poli, R.

    1999-03-17

    Compounds Cp*MH{sub 3}(dppe) (M = Mo, 1; W, 2) are oxidized chemically and electrochemically to the corresponding 17-electron cations 1{sup +} and 2{sup +}. Analogous oxidations of 1-d{sub 3} and 2-d{sub 3} provide 1{sup +}-d{sub 3} and 2{sup +}-d{sub 3}, respectively. Complex 2{sup +} is stable in CH{sub 2}Cl{sub 2}, THF and MeCN at room temperature. A single-crystal X-ray analysis of the PF{sub 6}{sup {minus}} salt of 2{sup +} shows a geometry optimization of the [CpWH{sub 3}(PH{sub 2}CH{sub 2}CH{sub 2}PH{sub 2})]{sup +} model at the B3LYP/LANL2DZ level. Identical calculations on the neutral analogue also reproduce the previously reported trigonal prismatic structure for 1. A blue shift in the M-H stretching vibrations upon oxidation for both Mo and W compounds indicates that a M-H bond strengthening accompanies the oxidation process. The DFT calculations (M-H bond lengths, BDE, and stretching frequencies) are in good agreement with the experimental results. Complex 1{sup +} decomposes in solution at room temperature by one or more of three different mechanisms depending on conditions: H{sub 2} reductive elimination, solvent-assisted disproportionation, or deprotonation. In THF or CH{sub 2}Cl{sub 2}, a reductive elimination of H{sub 2} affords the stable paramagnetic monohydride Cp*MoH(dppe)PF{sub 6} (3), which adds a molecule of solvent in CH{sub 2}Cl{sub 2}, THF, and MeCN. EPR studies show that the CH{sub 2}Cl{sub 2} molecule coordinates in a bidentate model to afford a 19-electron configuration. A solvent dependence of the decomposition rate [k(CH{sub 2}Cl{sub 2}) {approx} 7.8k(THF) at 0 C] and an inverse isotope effect [k{sub H}/k{sub d} = 0.50(3) in CH{sub 2}Cl{sub 2} at 0 C] indicate the nature of 1{sup +} as a classical trihydride and suggest a decomposition mechanism which involves equilibrium conversion to a nonclassical intermediate followed by a rate-determining associate exchange of H{sub 2} with a solvent molecule. In MeCN at 20 C, a solvent-assisted disproportionation (rate = k{sub disp}[1{sup +}]{sup 2}, k{sub disp} = 3.98(9) x 10{sup 3} s{sup {minus}} M{sup {minus}}) and a deprotonation by residual unoxidized 1 (rate = k{sub deprot}[1{sup +}][1], k{sub deprot} = 2.8(2) x 10{sup 2} s{sup {minus}} M{sup {minus}}) take place competitively, as shown by detailed cyclic voltammetric and thin-layer cyclic voltammetric studies. The stoichiometric chemical oxidation of 1 in MeCN leads to a mixture of [Cp*MoH{sub 2}(dppe)(MeCN)]{sup +} and [Cp*MoH(dppe)(MeCN){sub 2}]{sup 2+} by the disproportionation mechanism.

  10. Seasonal variation of artemisinin, artemisinic acid, and dihydroartemisinic acid in Brazilian, Chinese, and Swiss cultivars of Artemisia annua in WV, and effect of drying procedures on artemisinin and its precursors

    Technology Transfer Automated Retrieval System (TEKTRAN)

    The increased demand for artemisinin worldwide has led to the increased worldwide cultivation of Artemisia annua for the production of artemisinin. Artemisinin is a safe and effective sesquiterpene lactone effective against a range of diseases caused by protozoa (e.g., malaria, coccidiosis, leishma...

  11. Enhancing community partnerships during a public health emergency: the school-located vaccination clinics model in Kanawha County, WV during the 2009 influenza A (H1N1) pandemic.

    PubMed

    Gupta, Rahul

    2011-01-01

    Broad based community support is vital in developing a comprehensive national strategy to protect the public's health prior to, during and after a disaster such as pandemic influenza. When disaster strikes, the successful response is often dependent upon the degree of collaboration, coordination, and shared decision making occurring among a wide-ranging group of public and private stakeholders in the community. Since these preparedness and response activities must occur at a local level, the degree to which a certain community can become resilient after an event is directly dependent upon the success of the response activities. In order to protect its citizens, the Kanawha-Charleston Health Department (KCHD) led a comprehensive community based response to the 2009 Influenza A (H1N1) pandemic. By organizing a high level strategic team consisting of major community stakeholders, KCHD was able to develop broad based community support for its mitigation and countermeasure delivery strategies. The timely enhancement of the existing community partnerships enabled us to successfully conduct several response activities with local community support including school-located vaccination (SLV) clinics. We describe the process, results and challenges faced during our SLV clinics campaign which resulted in exceptionally high vaccination rates for school aged children compared to other jurisdictions across the nation. We also discuss how such partnerships can be sustained resulting in resilient communities and mention some strategies for those contemplating such partnerships in future public health emergency.

  12. 78 FR 53275 - Approval and Promulgation of Air Quality Implementation Plans; Ohio; Redesignation of the Ohio...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-29

    ...? On December 2, 2011 (76 FR 75464), EPA issued a final determination that the Parkersburg-Marietta and... standard. On November 30, 2012 (77 FR 71383, 77 FR 71371), EPA published notices proposing to approve Ohio..., 2012, requests for redesignation. On June 26, 2013 (78 FR 38256, 78 FR 38247), EPA...

  13. Safety on a Rural Community College Campus via Integrated Communications

    ERIC Educational Resources Information Center

    Gnage, Marie Foster; Dziagwa, Connie; White, Dave

    2009-01-01

    West Virginia University at Parkersburg uses a two-way emergency system as a baseline for emergency communications. The college has found that such a system, a key component of its safety and crisis management plan, can be integrated with other communication initiatives to provide focused security on the campus.

  14. 31 CFR 351.20 - What is the investment yield (interest) during the original maturity period of Series EE savings...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 1, 1982, by downloading from our website at www.savingsbonds.gov, contacting us by email at savbonds@bpd.treas.gov, or by writing us at the following address: Bureau of the Public Debt, Parkersburg, West... Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY BUREAU OF THE PUBLIC DEBT OFFERING...

  15. 31 CFR 351.23 - Are tables of redemption values available for bonds issued prior to May 1, 1995?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... PUBLIC DEBT OFFERING OF UNITED STATES SAVINGS BONDS, SERIES EE Maturities, Redemption Values, and... us by email at savbonds@bpd.treas.gov, or by writing us at the following address: Bureau of the Public Debt, Parkersburg, West Virginia 26106-1328. Series EE Savings Bonds With Issue Dates From May...

  16. 31 CFR 351.23 - Are tables of redemption values available for bonds issued prior to May 1, 1995?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PUBLIC DEBT OFFERING OF UNITED STATES SAVINGS BONDS, SERIES EE Maturities, Redemption Values, and... us by email at savbonds@bpd.treas.gov, or by writing us at the following address: Bureau of the Public Debt, Parkersburg, West Virginia 26106-1328. Series EE Savings Bonds With Issue Dates From May...

  17. 31 CFR 351.23 - Are tables of redemption values available for bonds issued prior to May 1, 1995?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... PUBLIC DEBT OFFERING OF UNITED STATES SAVINGS BONDS, SERIES EE Maturities, Redemption Values, and... us by email at savbonds@bpd.treas.gov, or by writing us at the following address: Bureau of the Public Debt, Parkersburg, West Virginia 26106-1328. Series EE Savings Bonds With Issue Dates From May...

  18. 31 CFR 351.23 - Are tables of redemption values available for bonds issued prior to May 1, 1995?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... PUBLIC DEBT OFFERING OF UNITED STATES SAVINGS BONDS, SERIES EE Maturities, Redemption Values, and... us by email at savbonds@bpd.treas.gov, or by writing us at the following address: Bureau of the Public Debt, Parkersburg, West Virginia 26106-1328. Series EE Savings Bonds With Issue Dates From May...

  19. 31 CFR 351.20 - What is the investment yield (interest) during the original maturity period of Series EE savings...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 1, 1982, by downloading from our website at www.savingsbonds.gov, contacting us by email at savbonds@bpd.treas.gov, or by writing us at the following address: Bureau of the Public Debt, Parkersburg, West... Finance (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY BUREAU OF THE PUBLIC DEBT OFFERING...

  20. 77 FR 73560 - Approval and Promulgation of Air Quality Implementation Plans; West Virginia; Redesignation of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-11

    ... national ambient air quality standard (NAAQS). The Parkersburg-Marietta Area is comprised of Wood County... Protection Agency, Region III, 1650 Arch Street, Philadelphia, Pennsylvania 19103. D. Hand Delivery: At the.... Environmental Protection Agency, Region III, 1650 Arch Street, Philadelphia, Pennsylvania 19103. Copies of...

  1. 1. VIEW EAST, SEED EXTRACTOR BUILDING ON LEFT, IMPLEMENT BUILDING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. VIEW EAST, SEED EXTRACTOR BUILDING ON LEFT, IMPLEMENT BUILDING ON RIGHT. (see also WV-237-5, WV-237-9, WV-237-h-1, WV-237-L-1) - Parsons Nursery, Seed Extractor Building, South side of U.S. Route 219, Parsons, Tucker County, WV

  2. Principal component and cluster analysis of morphological variables reveals multiple discrete sub-phenotypes in weaver mouse mutants.

    PubMed

    Martí, Joaquín; Santa-Cruz, María C; Serra, Roger; Valero, Oliver; Molina, Vanessa; Hervás, José P; Villegas, Sandra

    2013-06-01

    The present study evaluates the usefulness of the principal component analysis-based cluster analysis in the categorization of several sub-phenotypes in the weaver mutant by using several morphological parameters from the cerebellar cortex of control, heterozygous (+/wv) and homozygous (wv/wv) weaver mice. The quantified parameters were length of the cerebellar cortex, area of the external granular layer, area of the molecular layer, number of the external granular layer cells (EGL), and number of Purkinje cells (PCs). The analysis indicated that at postnatal day 8, the genotype +/wv presented three sub-phenotypes tagged as +/wv (0), +/wv (1) and +/wv (2), whereas two sub-phenotypes designated as wv (0)/wv (1) and wv (0)/wv (2) were identified in the genotype wv/wv. The number of PCs for the genotype +/wv and the number of EGL cells for the genotype wv/wv were the variables that discriminated the best among sub-phenotypes. Each one of the sub-phenotypes showed specific abnormalities in the cytoarchitecture of the cerebellar cortex as well as in the foliar pattern. In particular, the wv (0)/wv (1) and wv (0)/wv (2) sub-phenotypes had the most altered cytoarchitectonics, followed by the +/wv (2) sub-phenotype and then by the +/wv (1) one. The sub-phenotype +/wv (0) was the less affected one. Apart from reporting for the first time the coexistence of several sub-phenotypes in the weaver mutant, our approach provides a new statistical tool that can be used to assess cerebellar morphology.

  3. PROCEEDINGS: 1991 INTERNATIONAL CONFERENCE ON MUNICIPAL WASTE COMBUSTION - VOLUME 1. SESSIONS P, 0, 1A, 2A, 3A, 4A, 6A, 6B, 9C, AND 10B

    EPA Science Inventory

    The three-volumes document 82 presentations by authors from 15 countries at the Second International Conference on Municipal Waste Combustion (MWC) in Tampa, Florida, April 16-19, 1991. The Conference fostered the exchange of current information on research concerning MWC, ash di...

  4. The Heat Shock Factor A4A Confers Salt Tolerance and Is Regulated by Oxidative Stress and the Mitogen-Activated Protein Kinases MPK3 and MPK61[C][W][OPEN

    PubMed Central

    Pérez-Salamó, Imma; Papdi, Csaba; Rigó, Gábor; Zsigmond, Laura; Vilela, Belmiro; Lumbreras, Victoria; Nagy, István; Horváth, Balázs; Domoki, Mónika; Darula, Zsuzsa; Medzihradszky, Katalin; Bögre, László; Koncz, Csaba; Szabados, László

    2014-01-01

    Heat shock factors (HSFs) are principal regulators of plant responses to several abiotic stresses. Here, we show that estradiol-dependent induction of HSFA4A confers enhanced tolerance to salt and oxidative agents, whereas inactivation of HSFA4A results in hypersensitivity to salt stress in Arabidopsis (Arabidopsis thaliana). Estradiol induction of HSFA4A in transgenic plants decreases, while the knockout hsfa4a mutation elevates hydrogen peroxide accumulation and lipid peroxidation. Overexpression of HSFA4A alters the transcription of a large set of genes regulated by oxidative stress. In yeast (Saccharomyces cerevisiae) two-hybrid and bimolecular fluorescence complementation assays, HSFA4A shows homomeric interaction, which is reduced by alanine replacement of three conserved cysteine residues. HSFA4A interacts with mitogen-activated protein kinases MPK3 and MPK6 in yeast and plant cells. MPK3 and MPK6 phosphorylate HSFA4A in vitro on three distinct sites, serine-309 being the major phosphorylation site. Activation of the MPK3 and MPK6 mitogen-activated protein kinase pathway led to the transcriptional activation of the HEAT SHOCK PROTEIN17.6A gene. In agreement that mutation of serine-309 to alanine strongly diminished phosphorylation of HSFA4A, it also strongly reduced the transcriptional activation of HEAT SHOCK PROTEIN17.6A. These data suggest that HSFA4A is a substrate of the MPK3/MPK6 signaling and that it regulates stress responses in Arabidopsis. PMID:24676858

  5. 6. Photo copy of photograph, (original owned by Mary Gaudineer, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Photo copy of photograph, (original owned by Mary Gaudineer, Beckley, WV, copy at National Forest Office, Elkins, WV), Don Gaudineer, 1934. CONSTRUCTION OF FERNOW EXPERIMENTAL FOREST BUNKHOUSE AND GARAGE. (see also historic photograph WV-237-13) - Parsons Nursery, Fernow Experimental Forest Residence, South side of U.S. Route 219, Parsons, Tucker County, WV

  6. 78 FR 37788 - In the Matter of: Juan Ricardo Puente-Paez, Inmate Number #05086-379, FCI McDowell, Federal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-24

    ... McDowell, Federal Corrections Institution, Federal Satellite Low, P.O. Box 1009, Welch, WV 24801... Satellite Low, P.O. Box 1009, Welch, WV 24801, and when acting for or on behalf of Puente-Paez,...

  7. 30. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    30. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, 'tractor with cultivator operating'), photographer unknown, ca. 1938. VIEW SOUTHEAST, CULTIVATING SEEDLING TRANSPLANTS. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  8. 28. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    28. Photo copy of photograph, (original in Forest Service Office, Elkins, WV), photographer unknown, August 1939. D. A. OLIVER WITH A TRANSPLANT BOARD. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  9. 47 CFR 97.203 - Beacon station.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Radio Astronomy Observatory, P.O. Box 2, Green Bank, WV 24944. (1) The notification must include the... Radio Astronomy Observatory at Green Bank, Pocahontas County, WV, for itself or on behalf of the...

  10. 37. Photo copy of map, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    37. Photo copy of map, (original in Forest Service Office, Elkins, WV, 'Blister Rust Survey Map), 1930. PARSONS NURSERY SITE PLAN - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  11. 6. Photocopy of photograph, 1972. GRAFTON BRIDGE COLLAPSE IN AUGUST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Photocopy of photograph, 1972. GRAFTON BRIDGE COLLAPSE IN AUGUST OF 1890 (From the original collection of Miss Lois Heflin, Grafton, WV) - Northwestern Virginia Railroad, Grafton Bridge, Spanning Tygart Valley River, Grafton, Taylor County, WV

  12. View northwest, overview of building group: chicken house (HABS No. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View northwest, overview of building group: chicken house (HABS No. WV-267-D), wash house (267-C), Albert Thacker House (267-A), coal house (267-B) (left to right in photograph) - 3249 Cyrus Road (House), Cyrus, Wayne County, WV

  13. 6. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #246860), photographer unknown, ca. 1935. EQUIPMENT DETAIL, SEED WING REMOVER. - Parsons Nursery, Seed Extractor Building, South side of U.S. Route 219, Parsons, Tucker County, WV

  14. 78 FR 44874 - IFR Altitudes; Miscellaneous Amendments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-25

    ... ``significant rule'' under DOT Regulatory Policies and Procedures (44 FR 11034; February 26, 1979); and (3) does... RNAV Route Q72 Is Added To Read HACKS, WV FIX GEQUE, WV WP *18000 45000 *18000--GNSS MEA...

  15. 3. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #292222), photographer unknown, ca. 1935. VIEW EAST, CCC CAMP PARSONS, FOREST SERVICE TRUCK STORAGE ON LEFT, WATER TANK (DEMOLISHED), MESS HALL (DEMOLISHED). (see also historic photograph WV-237-20, WV-237-35) - Parsons Nursery, Civilian Conservation Corps Garage, South side of U.S. Route 219, Parsons, Tucker County, WV

  16. View northeast, overview of Albert Thacker building group: chicken house ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View northeast, overview of Albert Thacker building group: chicken house (HABS No. WV-267-D), wash house (267-C), privy (HABS No. WV-268-B), and house (267-A) (left to right in photograph) - 3249 Cyrus Road (House), Cyrus, Wayne County, WV

  17. Perspectives on Obesity and Its Treatment: Health Care Providers and the General Public in Rural West Virginia and Urban Baltimore

    ERIC Educational Resources Information Center

    Menez, Steven; Cheskin, Lawrence; Geller, Gail

    2013-01-01

    Objective: To determine and compare the perspectives of the general public and health care providers (HCPs) on obesity and its treatment in rural West Virginia (WV) and Baltimore, MD. Method: Surveys were completed in both locations by the general public (WV: "n" = 200; Baltimore: "n" = 171) and HCPs (WV: "n" = 25;…

  18. Weaver mutant mice exhibit long-term learning deficits under several measures of instrumental behavior.

    PubMed

    Derenne, Adam; Arsenault, Matthew L; Austin, David P; Weatherly, Jeffrey N

    2007-12-01

    Homozygous weaver mutant mice (wv/wv) exhibit symptoms that parallel Parkinson's disease, including motor deficits and the destruction of dopaminergic neurons as well as degeneration in the cerebellum and hippocampus. To develop a more complete behavioral profile of these organisms, groups of wv/wv, wv/+ mice and C57BL/6 mice were observed on a within-subjects basis under a fixed-interval schedule of reinforcement, a differential-reinforcement-of-low-rate-of-responding schedule, and a discrimination task in which a saccharin solution and tap water were concurrently available from two food cups. Under both reinforcement schedules, the wv/wv mice responded as frequently as the comparison subjects, but they responded in a manner that was inappropriate to the contingencies. Rather than respond with increasing frequency as the upcoming reinforcer became temporally proximate, wv/wv mice responded with decreasing probability as a function of the time since the previous reinforcer. Under the discrimination task, the wv/wv mice, unlike the controls, obtained saccharin over tap water at the level of chance. The findings suggest that weaver mutant mice express learning deficits similar to those found in other dopamine-deficient organisms.

  19. Cerebellar cortex development in the weaver condition presents regional and age-dependent abnormalities without differences in Purkinje cells neurogenesis.

    PubMed

    Martí, Joaquín; Santa-Cruz, María C; Hervás, José P; Bayer, Shirley A; Villegas, Sandra

    2016-01-01

    Ataxias are neurological disorders associated with the degeneration of Purkinje cells (PCs). Homozygous weaver mice (wv/wv) have been proposed as a model for hereditary cerebellar ataxia because they present motor abnormalities and PC loss. To ascertain the physiopathology of the weaver condition, the development of the cerebellar cortex lobes was examined at postnatal day (P): P8, P20 and P90. Three approaches were used: 1) quantitative determination of several cerebellar features; 2) qualitative evaluation of the developmental changes occurring in the cortical lobes; and 3) autoradiographic analyses of PC generation and placement. Our results revealed a reduction in the size of the wv/wv cerebellum as a whole, confirming previous results. However, as distinguished from these reports, we observed that quantified parameters contribute differently to the abnormal growth of the wv/wv cerebellar lobes. Qualitative analysis showed anomalies in wv/wv cerebellar cytoarchitecture, depending on the age and lobe analyzed. Such abnormalities included the presence of the external granular layer after P20 and, at P90, ectopic cells located in the molecular layer following several placement patterns. Finally, we obtained autoradiographic evidence that wild-type and wv/wv PCs presented similar neurogenetic timetables, as reported. However, the innovative character of this current work lies in the fact that the neurogenetic gradients of wv/wv PCs were not modified from P8 to P90. A tendency for the accumulation of late-formed PCs in the anterior and posterior lobes was found, whereas early-generated PCs were concentrated in the central and inferior lobes. These data suggested that wv/wv PCs may migrate properly to their final destinations. The extrapolation of our results to patients affected with cerebellar ataxias suggests that all cerebellar cortex lobes are affected with several age-dependent alterations in cytoarchitectonics. We also propose that PC loss may be regionally

  20. Cerebellar cortex development in the weaver condition presents regional and age-dependent abnormalities without differences in Purkinje cells neurogenesis.

    PubMed

    Martí, Joaquín; Santa-Cruz, María C; Hervás, José P; Bayer, Shirley A; Villegas, Sandra

    2016-01-01

    Ataxias are neurological disorders associated with the degeneration of Purkinje cells (PCs). Homozygous weaver mice (wv/wv) have been proposed as a model for hereditary cerebellar ataxia because they present motor abnormalities and PC loss. To ascertain the physiopathology of the weaver condition, the development of the cerebellar cortex lobes was examined at postnatal day (P): P8, P20 and P90. Three approaches were used: 1) quantitative determination of several cerebellar features; 2) qualitative evaluation of the developmental changes occurring in the cortical lobes; and 3) autoradiographic analyses of PC generation and placement. Our results revealed a reduction in the size of the wv/wv cerebellum as a whole, confirming previous results. However, as distinguished from these reports, we observed that quantified parameters contribute differently to the abnormal growth of the wv/wv cerebellar lobes. Qualitative analysis showed anomalies in wv/wv cerebellar cytoarchitecture, depending on the age and lobe analyzed. Such abnormalities included the presence of the external granular layer after P20 and, at P90, ectopic cells located in the molecular layer following several placement patterns. Finally, we obtained autoradiographic evidence that wild-type and wv/wv PCs presented similar neurogenetic timetables, as reported. However, the innovative character of this current work lies in the fact that the neurogenetic gradients of wv/wv PCs were not modified from P8 to P90. A tendency for the accumulation of late-formed PCs in the anterior and posterior lobes was found, whereas early-generated PCs were concentrated in the central and inferior lobes. These data suggested that wv/wv PCs may migrate properly to their final destinations. The extrapolation of our results to patients affected with cerebellar ataxias suggests that all cerebellar cortex lobes are affected with several age-dependent alterations in cytoarchitectonics. We also propose that PC loss may be regionally

  1. The effect of taste masking agents on in situ gelling pectin formulations for oral sustained delivery of paracetamol and ambroxol.

    PubMed

    Miyazaki, Shozo; Kubo, Wataru; Itoh, Kunihiko; Konno, Yasuhiro; Fujiwara, Mariko; Dairaku, Masatake; Togashi, Mitsuo; Mikami, Ryozo; Attwood, David

    2005-06-13

    The aim of this study was to examine the influence of polyhydric alcohols (taste masking agents) on the rheological properties of in situ gelling pectin formulations and on the in vitro and in vivo release of paracetamol and ambroxol from these formulations. Gelation of orally administered pectin solutions containing calcium in complexed form occurred on release of calcium in the acidic environment of the stomach. Inclusion of 10% (w/v) sorbitol in 2% (w/v) pectin sols reduced the viscosity and ensured Newtonian flow properties. Xylitol and mannitol in similar concentrations were less effective in reducing viscosity; sucrose increased viscosity and caused non-Newtonian flow. The in vitro release of paracetamol from 2% (w/v) pectin gels formulated with 10% (w/v) of sorbitol, erythritol, xylitol or mannitol, and of ambroxol from 2% (w/v) pectin gels containing 10% (w/v) sorbitol, followed diffusion-controlled kinetics. Pectin gels (2%, w/v) containing sorbitol (10%, w/v) sustained the release of paracetamol in the rat stomach and bioavailabilities of approximately 90% of those from an orally administered paracetamol syrup were achieved. Sustained release of ambroxol from in situ gelling formulations was achieved with pectin concentrations of 1.5 and 1% (w/v) and a sorbitol concentration of 10% (w/v). PMID:15907595

  2. The effect of taste masking agents on in situ gelling pectin formulations for oral sustained delivery of paracetamol and ambroxol.

    PubMed

    Miyazaki, Shozo; Kubo, Wataru; Itoh, Kunihiko; Konno, Yasuhiro; Fujiwara, Mariko; Dairaku, Masatake; Togashi, Mitsuo; Mikami, Ryozo; Attwood, David

    2005-06-13

    The aim of this study was to examine the influence of polyhydric alcohols (taste masking agents) on the rheological properties of in situ gelling pectin formulations and on the in vitro and in vivo release of paracetamol and ambroxol from these formulations. Gelation of orally administered pectin solutions containing calcium in complexed form occurred on release of calcium in the acidic environment of the stomach. Inclusion of 10% (w/v) sorbitol in 2% (w/v) pectin sols reduced the viscosity and ensured Newtonian flow properties. Xylitol and mannitol in similar concentrations were less effective in reducing viscosity; sucrose increased viscosity and caused non-Newtonian flow. The in vitro release of paracetamol from 2% (w/v) pectin gels formulated with 10% (w/v) of sorbitol, erythritol, xylitol or mannitol, and of ambroxol from 2% (w/v) pectin gels containing 10% (w/v) sorbitol, followed diffusion-controlled kinetics. Pectin gels (2%, w/v) containing sorbitol (10%, w/v) sustained the release of paracetamol in the rat stomach and bioavailabilities of approximately 90% of those from an orally administered paracetamol syrup were achieved. Sustained release of ambroxol from in situ gelling formulations was achieved with pectin concentrations of 1.5 and 1% (w/v) and a sorbitol concentration of 10% (w/v).

  3. Cardiac sympathetic modulation in response to apneas/hypopneas through heart rate variability analysis.

    PubMed

    Chouchou, Florian; Pichot, Vincent; Barthélémy, Jean-Claude; Bastuji, Hélène; Roche, Frédéric

    2014-01-01

    Autonomic dysfunction is recognized to contribute to cardiovascular consequences in obstructive sleep apnea/hypopnea syndrome (OSAHS) patients who present predominant cardiovascular sympathetic activity that persists during wakefulness. Here, we examined 1) the factors that influence sympathetic cardiac modulation in response to apneas/hypopneas; and 2) the influence of autonomic activity during apneas/hypopneas on CA. Sixteen OSAHS patients underwent in-hospital polysomnography. RR interval (RR) and RR spectral analysis using wavelet transform were used to study parasympathetic (high frequency power: HF(WV)) and sympathetic (low frequency power: LF(WV) and LF(WV)/HF(WV) ratio) activity before and after apnea/hypopnea termination. Autonomic cardiac modulations were compared according to sleep stage, apnea/hypopnea type and duration, arterial oxygen saturation, and presence of CA. At apnea/hypopnea termination, RR decreased (p<0.001) while LF(WV) (p = 0.001) and LF(WV)/HF(WV) ratio (p = 0.001) increased. Only RR and LF(WV)/HF(WV) ratio changes were higher when apneas/hypopneas produced CA (p = 0.030 and p = 0.035, respectively) or deep hypoxia (p = 0.023 and p = 0.046, respectively). Multivariate statistical analysis showed that elevated LF(WV) (p = 0.006) and LF(WV)/HF(WV) ratio (p = 0.029) during apneas/hypopneas were independently related to higher CA occurrence. Both the arousal and hypoxia processes may contribute to sympathetic cardiovascular overactivity by recurrent cardiac sympathetic modulation in response to apneas/hypopneas. Sympathetic overactivity also may play an important role in the acute central response to apneas/hypopneas, and in the sleep fragmentation.

  4. Tomography of many-body weak values: Mach-Zehnder interferometry.

    PubMed

    Shpitalnik, Vadim; Gefen, Yuval; Romito, Alessandro

    2008-11-28

    We propose and study a weak value (WV) protocol in the context of a solid state setup, specifically, an electronic Mach-Zehnder interferometer. This is the first specific proposal to measure both the real and imaginary part (i.e., complete tomography) of a WV. We also analyze the manifestation of many-body physics in the WV to be measured, including finite temperature and shot-noise-like contributions.

  5. 5. VIEW FROM SLIGHTLY FARTHER DOWN SERVICE ROAD, LOOKING SOUTHEAST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. VIEW FROM SLIGHTLY FARTHER DOWN SERVICE ROAD, LOOKING SOUTHEAST AT ELECTRICITY SUPPLY BUILDING, LABORATORY, AND OFFICE. - Standard Lime & Stone Quarry, County Route 27, Millville, Jefferson County, WV

  6. 12. TRANSMISSION GEARING SHOWING RELATION TO SEGMENT GEAR ON WATERWHEEL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. TRANSMISSION GEARING SHOWING RELATION TO SEGMENT GEAR ON WATERWHEEL william E. Barrett, photographer, 1973 (copy negative) - Thomas Shepherd's Grist Mill, High Street Vicinity, Shepherdstown, Jefferson County, WV

  7. 7. William E. Barrett, Photographer, August 1975. LOG PONDS LOOKING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. William E. Barrett, Photographer, August 1975. LOG PONDS LOOKING WEST FROM POWERHOUSE ROOF. TRANSFORMER SHED IN FOREGROUND. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  8. 30 CFR 20.14 - Instructions for handling future changes in lamp design.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MINE LAMPS OTHER THAN STANDARD CAP..., 765 Technology Drive, Triadelphia, WV 26059, requesting an extension of the original approval...

  9. 7. STONE PIER OF ORIGINAL WATERWHEEL INSTALLATION DOWNSTREAM FROM MILL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. STONE PIER OF ORIGINAL WATERWHEEL INSTALLATION DOWNSTREAM FROM MILL William E. Barrett, photographer, 1973 (copy negative) - Thomas Shepherd's Grist Mill, High Street Vicinity, Shepherdstown, Jefferson County, WV

  10. 30 CFR 36.3 - Consultation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., 765 Technology Drive, Triadelphia, WV 26059, to discuss with qualified MSHA personnel proposed mobile... MINING PRODUCTS APPROVAL REQUIREMENTS FOR PERMISSIBLE MOBILE DIESEL-POWERED TRANSPORTATION...

  11. 30 CFR 36.3 - Consultation.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., 765 Technology Drive, Triadelphia, WV 26059, to discuss with qualified MSHA personnel proposed mobile... MINING PRODUCTS APPROVAL REQUIREMENTS FOR PERMISSIBLE MOBILE DIESEL-POWERED TRANSPORTATION...

  12. 30 CFR 36.3 - Consultation.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., 765 Technology Drive, Triadelphia, WV 26059, to discuss with qualified MSHA personnel proposed mobile... MINING PRODUCTS APPROVAL REQUIREMENTS FOR PERMISSIBLE MOBILE DIESEL-POWERED TRANSPORTATION...

  13. 30 CFR 36.3 - Consultation.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., 765 Technology Drive, Triadelphia, WV 26059, to discuss with qualified MSHA personnel proposed mobile... MINING PRODUCTS APPROVAL REQUIREMENTS FOR PERMISSIBLE MOBILE DIESEL-POWERED TRANSPORTATION...

  14. 30 CFR 36.3 - Consultation.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., 765 Technology Drive, Triadelphia, WV 26059, to discuss with qualified MSHA personnel proposed mobile... MINING PRODUCTS APPROVAL REQUIREMENTS FOR PERMISSIBLE MOBILE DIESEL-POWERED TRANSPORTATION...

  15. 39. Photo copy of site plan, (original in Forest Service ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    39. Photo copy of site plan, (original in Forest Service Office, Elkins, WV, 'Parsons Nursery Special Use Permit, West Virginia Department of Natural Resources'), 1969. PARSONS NURSERY SITE PLAN. CORROLATES TO PARSONS NURSERY AT TIME OF FLOOD, NOVEMBER, 1985. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  16. 27. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    27. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #292219, 'Tree nurseries-transplanting-transplanting beds'), D. A. Oliver, 1934. VIEW SOUTHWEST, TRANSPLANT SHED AND MAN WITH TRANSPLANT BOARD. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  17. 26. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. Photo copy of photograph, (original in Forest Service Office, Elkins, WV), photographer unknown, ca. 1936. VIEW NORTHWEST, GARAGE (DEMOLISHED), NURSERY MANAGER'S GARAGE AND RESIDENCE, AND PACKING BUILDING, TRANSPLANT SHEDS AND PLOW IN FOREGROUND. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  18. 29. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    29. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #292218, 'Planting with 10 ft. transplant board'), D. A. Oliver, 1934. VIEW EAST, FIRMING EARTH BEFORE REMOVING TRANSPLANT BOARD FROM NEWLY TRANSPLANTED SEEDLINGS. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  19. 1. View northeast, west side and south end, with farmhouse ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. View northeast, west side and south end, with farmhouse (WV-266-A) at left background - Abraham Cyrus Farmstead, Wash House, About 20 feet south-southwest of farmhouse at 3271 Cyrus Road (County Road 1/6), Cyrus, Wayne County, WV

  20. 7. Photo copy of blue print sheet, (original in Forest ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Photo copy of blue print sheet, (original in Forest Service Office, Elkins, WV), George W. Root, draftsman, July, 1931. MAIN FLOOR PLAN SHOWING JOIST FRAMING, FOUNDATION PLAN, MAIN FLOOR PLAN, SECOND FLOOR PLAN, END ELEVATION AT SLOUGH. - Parsons Nursery, Packing Building, South side of U.S. Route 219, Parsons, Tucker County, WV

  1. 4. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #302582, 'Insect/disease control'), D. A. Oliver, May 1935. VIEW NORTHEAST. - Parsons Nursery, Packing Building, South side of U.S. Route 219, Parsons, Tucker County, WV

  2. 75 FR 63475 - Radio Broadcasting Services; AM or FM Proposals To Change The Community of License

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... COMMISSION Radio Broadcasting Services; AM or FM Proposals To Change The Community of License AGENCY: Federal Communications Commission. ACTION: Notice. SUMMARY: The following applicants filed AM or FM proposals to change..., From CRAIGSVILLE, WV, To WEBSTER SPRINGS, WV; ENTRAVISION HOLDINGS, LLC, Station KVVA-FM, Facility...

  3. 75 FR 31768 - Procurement List Proposed Additions and Deletions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-04

    .... Contracting Activity: Dept of Trans, Federal Aviation Administration, College Park, GA. Service Type/Location..., Charleston, WV. NPA: Goodwill Industries of Kanawha Valley, Inc., Charleston, WV. Contracting Activity: DEPT... Activity: Dept of Commerce, National Oceanic and Atmospheric Administration, Norfolk, VA. Service...

  4. 40 CFR 81.349 - West Virginia.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Remainder of State X West Virginia—Carbon Monoxide Designated Area Designation Date 1 Type Classification.... Huntington-Ashland, WV-KY-OH: Cabell County Nonattainment. Mason County (part) Nonattainment. Graham Tax District Wayne County Nonattainment. Marion County, WV (aka Fairmont CBSA): Harrison County (part)...

  5. 7. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #246865, 'Drying racks'), D. A. Oliver, 1934. FURNISHING DETAIL, DRYING RACKS. - Parsons Nursery, Cone Drying Shed, South side of U.S. Route 219, Parsons, Tucker County, WV

  6. 23. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    23. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #248336, 'Tree nurseries-seed bed seeding machine'), D. A. Oliver, 1930. VIEW WEST, SEEDING MACHINE. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  7. 22. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    22. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #244025, 'seed planter'), D. A. Oliver, 1930. VIEW EAST, FRONT OF WORKSHOP/WAREHOUSE, SEED BED PLANTER. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  8. 5. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #298181), D. A. Oliver, 1934. LOWER FLOOR, LOOKING WEST, SEED EXTRACTOR. - Parsons Nursery, Seed Extractor Building, South side of U.S. Route 219, Parsons, Tucker County, WV

  9. 4. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #298180, 'seed extracting equipment'), D. A. Oliver, 1934. LOWER FLOOR, LOOKING WEST, SEED EXTRACTOR. - Parsons Nursery, Seed Extractor Building, South side of U.S. Route 219, Parsons, Tucker County, WV

  10. 78 FR 45937 - Final Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-30

    ...) and where applicable, in the supporting Flood Insurance Study (FIS) reports have been made final for... Areas Docket No.: FEMA-B-1270 City of Point Pleasant City Hall, 400 Viand Street, Point Pleasant, WV 25550. Town of Hartford Town Hall, 133 2nd Street, Hartford, WV 25247. Town of Henderson Town Hall,...

  11. Passing on a Culture: West Virginia Traditional Musical Heritage and the Allegheny Echoes Programme

    ERIC Educational Resources Information Center

    Swain, Leila Ryland

    2010-01-01

    Allegheny Echoes is a summer programme of instruction and performance of music and poetry held in Marlinton, WV. The Bing Brothers learned their traditional music from the Hammons family of Pocahontas County, WV, in an informal setting of friendship and collaboration. The Hammons family was recorded in the 1970s by Alan Jabbour and others; the…

  12. 76 FR 79593 - Approval, and Promulgation of Air Quality Implementation Plans; Ohio; Redesignation of the Ohio...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-22

    ... redesignation of the Ohio portion of the Huntington-Ashland (OH-KY-WV) nonattainment area to attainment of the... entire Huntington-Ashland (OH-KY-WV) area continues to attain the 1997 annual PM 2.5 standard. EPA is... implementation regulation regarding the 1997 p.m. 2.5 NAAQS. DATES: Comments must be received on or...

  13. 40 CFR 52.1880 - Control strategy: Particulate matter.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Parkerburg-Marietta, WV-OH and the Wheeling, WV-OH PM2.5 nonattainment areas have attained the 1997 PM2.5 NAAQS. These determinations, in accordance with 40 CFR 52.1004(c), suspend the requirements for these... accordance with 40 CFR 52.1004(c), suspends the requirements for this Area to submit an...

  14. Case Study: Effect of Handrim Diameter on Performance in a Paralympic Wheelchair Athlete

    ERIC Educational Resources Information Center

    Costa, Gabriel Brizuela; Rubio, Miguel Polo; Belloch, Salvador Llana; Soriano, Pedro Perez

    2009-01-01

    This study, with a top T-52 class athlete, determines the relationship between stroke frequency (SF) and push time (PT) and wheelchair velocity (Wv) using different handrim diameters (HD) and the effect of different HDs on the athlete's heart rate (HR) and blood lactate (LACT) at competition speeds. Wv shows a linear-direct relationship with SF…

  15. First records of Nocomis biguttatus (Hornyhead Chub) from West Virginia discovered in museum voucher specimens

    USGS Publications Warehouse

    Welsh, Stuart; Cincotta, Daniel A.; Starnes, Wayne C.

    2013-01-01

    Specimens of Nocomis biguttatus (Hornyhead Chub) from South Fork Hughes River (Little Kanawha River drainage, WV) were discovered in two museum lots at the North Carolina Museum of Natural Sciences. These accessions, collected in 1960 and 1966, represent an addition to the state fauna and are the first distribution records for this species from the Appalachian Plateau, WV

  16. View southeast, overview of building group: coal house (HABS No. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View southeast, overview of building group: coal house (HABS No. WV-267-B), large tree, Albert Thacker House (267-A), wash house (267-C), Eustace Chadwick House (268-A) (on lot to south), chicken house (267-D), and small tree (left to right in photograph) - 3249 Cyrus Road (House), Cyrus, Wayne County, WV

  17. Increasing alcohol yield by selected yeast fermentation of sweet sorghum. I. Evaluation of yeast strains for ethanol production

    SciTech Connect

    de Mancilha, I.M.; Pearson, A.M.; Waller, J.; Hogaboam, G.J.

    1984-01-01

    A study was conducted for the purpose of evaluating and selecting yeast strains for their ability to produce ethanol using sweet sorghum juice as the substrate. Stalks of sweet sorghum were obtained by cutting off the tops and stripping away the leaves. Fermentation media were prepared by diluting or adding dextrose to the sorghum juice to give a sugar concentration of either 10% (w/v) or 20% (w/v). All yeast strains were first tested in 10% (w/v) total sugar medium. Those strains showing more than 90% sugar conversion efficiency were further tested in 20% (w/v) total sugar medium. Active cultures for inoculation were prepared by growing the yeast strains on the fermentation medium (10% (w/v) total sugar) for 24 h. Then the cultures were added to the fermentation media at a rate of 2%.

  18. West Virginia Full-Scale Solar Energy Team Growing the Mountain State Energy Economy by Reaching our Full Solar Potential

    SciTech Connect

    Inc., Geostellar,

    2012-02-15

    The WV Team will design and demonstrate a complete set of systems and processes for automating the identification of residential and light commercial solar opportunities, evaluating project finance options, securing permits and arranging for interconnections to the utility grid. These operations will be supported by the predictive qualification and feasibility of residential and light commercial solar energy opportunities in WV based on the current solar LCOE and potential state-wide policy initiatives. Through the WV Department of Commerce and its Division of Energy, the WV Team will coordinate with all 55 county development authorities in West Virginia, as well as a number of local and municipal authorities responsible for zoning and building code ordinances to support and implement a statewide, integrated set of regulations and administrative services. Additionally the WV Team will work with the State administration and legislature to develop incentives that will promote the financing of residential and light commercial solar projects.

  19. A systematic evaluation of solubility enhancing excipients to enable the generation of permeability data for poorly soluble compounds in Caco-2 model.

    PubMed

    Shah, Devang; Paruchury, Sundeep; Matta, Muralikrishna; Chowan, Gajendra; Subramanian, Murali; Saxena, Ajay; Soars, Matthew G; Herbst, John; Haskell, Roy; Marathe, Punit; Mandlekar, Sandhya

    2014-01-01

    The study presented here identified and utilized a panel of solubility enhancing excipients to enable the generation of flux data in the Human colon carcinoma (Caco-2) system for compounds with poor solubility. Solubility enhancing excipients Dimethyl acetamide (DMA) 1 % v/v, polyethylene glycol (PEG) 400 1% v/v, povidone 1% w/v, poloxamer 188 2.5% w/v and bovine serum albumin (BSA) 4% w/v did not compromise Caco-2 monolayer integrity as assessed by trans-epithelial resistance measurement (TEER) and Lucifer yellow (LY) permeation. Further, these excipients did not affect P-glycoprotein (P-gp) mediated bidirectional transport of digoxin, permeabilities of high (propranolol) or low permeability (atenolol) compounds, and were found to be inert to Breast cancer resistant protein (BCRP) mediated transport of cladribine. This approach was validated further using poorly soluble tool compounds, atazanavir (poloxamer 188 2.5% w/v) and cyclosporine A (BSA 4% w/v) and also applied to new chemical entity (NCE) BMS-A in BSA 4% w/v, for which Caco-2 data could not be generated using the traditional methodology due to poor solubility (<1 µM) in conventional Hanks balanced salt solution (HBSS). Poloxamer 188 2.5% w/v increased solubility of atazanavir by >8 fold whereas BSA 4% w/v increased the solubility of cyclosporine A and BMS-A by >2-4 fold thereby enabling permeability as well as efflux liability estimation in the Caco-2 model with reasonable recovery values. To conclude, addition of excipients such as poloxamer 188 2.5% w/v and BSA 4% w/v to HBSS leads to a significant improvement in the solubility of the poorly soluble compounds resulting in enhanced recoveries without modulating transporter-mediated efflux, expanding the applicability of Caco-2 assays to poorly soluble compounds.

  20. Identification of a novel multiple kinase inhibitor with potent antiviral activity against influenza virus by reducing viral polymerase activity

    SciTech Connect

    Sasaki, Yutaka; Kakisaka, Michinori; Chutiwitoonchai, Nopporn; Tajima, Shigeru; Hikono, Hirokazu; Saito, Takehiko; Aida, Yoko

    2014-07-18

    Highlights: • Screening of 50,000 compounds and subsequent lead optimization identified WV970. • WV970 has antiviral effects against influenza A, B and highly pathogenic viral strains. • WV970 inhibits viral genome replication and transcription. • A target database search suggests that WV970 may bind to a number of kinases. • KINOMEscan screening revealed that WV970 has inhibitory effects on 15 kinases. - Abstract: Neuraminidase inhibitors are the only currently available influenza treatment, although resistant viruses to these drugs have already been reported. Thus, new antiviral drugs with novel mechanisms of action are urgently required. In this study, we identified a novel antiviral compound, WV970, through cell-based screening of a 50,000 compound library and subsequent lead optimization. This compound exhibited potent antiviral activity with nanomolar IC{sub 50} values against both influenza A and B viruses but not non-influenza RNA viruses. Time-of-addition and indirect immunofluorescence assays indicated that WV970 acted at an early stage of the influenza life cycle, but likely after nuclear entry of viral ribonucleoprotein (vRNP). Further analyses of viral RNA expression and viral polymerase activity indicated that WV970 inhibited vRNP-mediated viral genome replication and transcription. Finally, structure-based virtual screening and comprehensive human kinome screening were used to demonstrate that WV970 acts as a multiple kinase inhibitor, many of which are associated with influenza virus replication. Collectively, these results strongly suggest that WV970 is a promising anti-influenza drug candidate and that several kinases associated with viral replication are promising drug targets.

  1. Multivesicular liposomal bupivacaine at the sciatic nerve.

    PubMed

    McAlvin, J Brian; Padera, Robert F; Shankarappa, Sahadev A; Reznor, Gally; Kwon, Albert H; Chiang, Homer H; Yang, Jason; Kohane, Daniel S

    2014-05-01

    Clinical translation of sustained release formulations for local anesthetics has been limited by adverse tissue reaction. Exparel™ (DepoFoam bupivacaine) is a new liposomal local anesthetic formulation whose biocompatibility near nerve tissue is not well characterized. Exparel™ injection caused sciatic nerve blockade in rats lasting 240 min compared to 120 min for 0.5% (w/v) bupivacaine HCl and 210 min for 1.31% (w/v) bupivacaine HCl (same bupivacaine content as Exparel™). On histologic sections four days after injection, median inflammation scores in the Exparel™ group (2.5 of 4) were slightly higher than in groups treated with bupivacaine solutions (score 2). Myotoxicity scores in the Exparel™ group (2.5 of 6) were similar to in the 0.5% (w/v) bupivacaine HCl group (3), but significantly less than in the 1.31% (w/v) bupivacaine HCl group (5). After two weeks, inflammation from Exparel™ (score 2 of 6) was greater than from 0.5% (w/v) bupivacaine HCl (1) and similar to that from 1.31% (w/v) bupivacaine HCl (1). Myotoxicity in all three groups was not statistically significantly different. No neurotoxicity was detected in any group. Tissue reaction to Exparel™ was similar to that of 0.5% (w/v) bupivacaine HCl. Surveillance for local tissue injury will be important during future clinical evaluation.

  2. Cellulase and Xylanase Production by Penicillium echinulatum in Submerged Media Containing Cellulose Amended with Sorbitol

    PubMed Central

    Todero Ritter, Carla Eliana; Camassola, Marli; Zampieri, Denise; Silveira, Mauricio Moura; Dillon, Aldo José Pinheiro

    2013-01-01

    The present work investigated the use of sorbitol as a soluble carbon source, in association with cellulose, to produce cellulases and xylanases in submerged cultures of Penicillium echinulatum 9A02S1. Because cellulose is an insoluble carbon source, in cellulase production, there are some problems with rheology and oxygen transfer. The submerged fermentations containing media composed of 0, 0.25, 0.5, 0.75, and 1% (w/v) sorbitol and cellulose that were added at different times during the cultivation; 0.2% (w/v) soy bran; 0.1% (w/v) wheat bran; and a solution of salts. The highest filter paper activity (FPA) (1.95  ±  0.04 IU·mL−1) was obtained on the seventh day in the medium containing 0.5% (w/v) sorbitol and 0.5% (w/v) cellulose added 24 h after the start of cultivation. However, the CMCases showed an activity peak on the sixth day (9.99 ± 0.75 IU·mL−1) in the medium containing 0.75% (w/v) sorbitol and 0.75% (w/v) cellulose added after 12 h of cultivation. The xylanases showed the highest activity in the medium with 0.75% (w/v) sorbitol and 0.25% (w/v) cellulose added 36 h after the start of cultivation. This strategy enables the reduction of the cellulose concentration, which in high concentrations can cause rheological and oxygen transfer problems. PMID:24058733

  3. Cellulase and Xylanase Production by Penicillium echinulatum in Submerged Media Containing Cellulose Amended with Sorbitol.

    PubMed

    Todero Ritter, Carla Eliana; Camassola, Marli; Zampieri, Denise; Silveira, Mauricio Moura; Dillon, Aldo José Pinheiro

    2013-01-01

    The present work investigated the use of sorbitol as a soluble carbon source, in association with cellulose, to produce cellulases and xylanases in submerged cultures of Penicillium echinulatum 9A02S1. Because cellulose is an insoluble carbon source, in cellulase production, there are some problems with rheology and oxygen transfer. The submerged fermentations containing media composed of 0, 0.25, 0.5, 0.75, and 1% (w/v) sorbitol and cellulose that were added at different times during the cultivation; 0.2% (w/v) soy bran; 0.1% (w/v) wheat bran; and a solution of salts. The highest filter paper activity (FPA) (1.95  ±  0.04 IU·mL(-1)) was obtained on the seventh day in the medium containing 0.5% (w/v) sorbitol and 0.5% (w/v) cellulose added 24 h after the start of cultivation. However, the CMCases showed an activity peak on the sixth day (9.99 ± 0.75 IU·mL(-1)) in the medium containing 0.75% (w/v) sorbitol and 0.75% (w/v) cellulose added after 12 h of cultivation. The xylanases showed the highest activity in the medium with 0.75% (w/v) sorbitol and 0.25% (w/v) cellulose added 36 h after the start of cultivation. This strategy enables the reduction of the cellulose concentration, which in high concentrations can cause rheological and oxygen transfer problems.

  4. An Assessment of Worldview-2 Imagery for the Classification Of a Mixed Deciduous Forest

    NASA Astrophysics Data System (ADS)

    Carter, Nahid

    Remote sensing provides a variety of methods for classifying forest communities and can be a valuable tool for the impact assessment of invasive species. The emerald ash borer (Agrilus planipennis) infestation of ash trees (Fraxinus) in the United States has resulted in the mortality of large stands of ash throughout the Northeast. This study assessed the suitability of multi-temporal Worldview-2 multispectral satellite imagery for classifying a mixed deciduous forest in Upstate New York. Training sites were collected using a Global Positioning System (GPS) receiver, with each training site consisting of a single tree of a corresponding class. Six classes were collected; Ash, Maple, Oak, Beech, Evergreen, and Other. Three different classifications were investigated on four data sets. A six class classification (6C), a two class classification consisting of ash and all other classes combined (2C), and a merging of the ash and maple classes for a five class classification (5C). The four data sets included Worldview-2 multispectral data collection from June 2010 (J-WV2) and September 2010 (S-WV2), a layer stacked data set using J-WV2 and S-WV2 (LS-WV2), and a reduced data set (RD-WV2). RD-WV2 was created using a statistical analysis of the processed and unprocessed imagery. Statistical analysis was used to reduce the dimensionality of the data and identify key bands to create a fourth data set (RD-WV2). Overall accuracy varied considerably depending upon the classification type, but results indicated that ash was confused with maple in a majority of the classifications. Ash was most accurately identified using the 2C classification and RD-WV2 data set (81.48%). A combination of the ash and maple classes yielded an accuracy of 89.41%. Future work should focus on separating the ash and maple classifiers by using data sources such as hyperspectral imagery, LiDAR, or extensive forest surveys.

  5. 14. INTERIOR OF POWER PLANT LOOKING SOUTHEAST AT ELECTRICAL PANEL. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. INTERIOR OF POWER PLANT LOOKING SOUTHEAST AT ELECTRICAL PANEL. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  6. 28. Photocopied 1973 from The Rig & Reel Magazine, (March, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    28. Photocopied 1973 from The Rig & Reel Magazine, (March, 1923) p. 2. INTERIOR OF CENTRAL POWERHOUSE AT VOLCANO - NOW DISMANTLED. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  7. 26. Photocopied 1973 from The Rig & Reel Magazine, (March, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. Photocopied 1973 from The Rig & Reel Magazine, (March, 1923) p. 1. TYPICAL WELL HOOK-UP. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  8. 25. Photocopied 1973 from The Rig & Reel Magazine, (March, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    25. Photocopied 1973 from The Rig & Reel Magazine, (March, 1923) p. 1. TYPICAL ENDLESS-WIRE RIG IN VOLCANO. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  9. 34. William E. Barrett, Photographer, 1973. ENGINE HOUSE, WIRES FROM ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    34. William E. Barrett, Photographer, 1973. ENGINE HOUSE, WIRES FROM IT, AND COMPLETE WELL DERAIL, WHEELS. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  10. 31. William E. Barrett, Photographer, 1973. WELL WITH POLE DERRICK ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    31. William E. Barrett, Photographer, 1973. WELL WITH POLE DERRICK AND COMPLETE SET OF WHEELS, ROADWAY ACCESS. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  11. 40. William E. Barrett, Photographer, 1973. SHOP, YPOLE, MR. WEST'S ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    40. William E. Barrett, Photographer, 1973. SHOP, Y-POLE, MR. WEST'S HOUSE AND POLE SWELL - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  12. 46. William E. Barrett, Photographer, 1977. SAME SHOWING MORE ROOF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    46. William E. Barrett, Photographer, 1977. SAME SHOWING MORE ROOF DAMAGE AND NOT QUITE AS WIDE AN ANGLE VIEW. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  13. 41. William E. Barrett, Photographer, 1973. MR. WEST'S HOUSE, MR. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    41. William E. Barrett, Photographer, 1973. MR. WEST'S HOUSE, MR. WEST ON PORCH AND THE ARBOR THAT IS OVER 100 YEARS OLD. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  14. 32. William E. Barrett, Photographer, 1973. DEADEND WELL WITH WOODEN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    32. William E. Barrett, Photographer, 1973. DEAD-END WELL WITH WOODEN OIL TANK, PIPE ROCKER ARM. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  15. 27. Photocopied 1973 from The Rig & Reel Magazine, (March, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    27. Photocopied 1973 from The Rig & Reel Magazine, (March, 1923) p. 5. EARLIER ENDLESS-WIRE TRANSMISSION NOW IN RUINS. - West Oil Company Endless Wire Pumping Station, U.S. Route 50 (Volcano vicinity), Petroleum, Ritchie County, WV

  16. 27. Credit JTL. Second floor, detail of Eureka horizontal wheat ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    27. Credit JTL. Second floor, detail of Eureka horizontal wheat scourer, by S. Howes Co., (Silver Creek, NY). After leaving scourer, grain passed directly to the Midget Marvel Machine. - Bunker Hill Mill, County Route 26, Bunker Hill, Berkeley County, WV

  17. Libraries in West Virginia: MedlinePlus

    MedlinePlus

    ... this page: https://medlineplus.gov/libraries/westvirginia.html Libraries in West Virginia To use the sharing features ... enable JavaScript. Bridgeport United Hospital Center Health Sciences Library 327 Medical Park Dr Bridgeport, WV 26330 681- ...

  18. 4. GENERAL VIEW LOOKING WEST AT MACHINE SHOP IN KEYSER. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. GENERAL VIEW LOOKING WEST AT MACHINE SHOP IN KEYSER. OLD TRAIN SHED TO RIGHT OF MACHINE SHOP. - Baltimore & Ohio Railroad, Keyser Machine Shop, State Route 46 Northwest of Spring Street, Keyser, Mineral County, WV

  19. 3. Photocopied 1974 from The Baltimore and Ohio Railroad and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Photocopied 1974 from The Baltimore and Ohio Railroad and Its Branches, from the Lakes to the Sea, Baltimore, 1872. EARLY VIEW AT TRACK LEVEL. - Baltimore & Ohio Railroad, Tray Run Viaduct, Spanning Tray Run, Rowlesburg, Preston County, WV

  20. DETAIL OF STANDARD INTERLOCKING MACHINE OPERATING LEVERS. LOCKING MECHANISM IS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL OF STANDARD INTERLOCKING MACHINE OPERATING LEVERS. LOCKING MECHANISM IS BELOW FLOOR. BOXES BEHIND SOME LEVERS HOUSE ELECTRICAL CONTACTS FOR SIGNALS. - Baltimore & Ohio Railroad, Z Tower, State Route 46, Keyser, Mineral County, WV

  1. 1. LOOKING SOUTHWEST TOWARD NORTH AND WEST SIDES OF OFFICE; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. LOOKING SOUTHWEST TOWARD NORTH AND WEST SIDES OF OFFICE; LABORATORY AND ELECTRICITY SUPPLY HOUSE TO THE RIGHT. - Standard Lime & Stone Quarry, Office, County Route 27, Millville, Jefferson County, WV

  2. 45. William E. Barrett, Photographer, August 1975. EARLY STEAM GENERATING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    45. William E. Barrett, Photographer, August 1975. EARLY STEAM GENERATING UNIT USED TO PRODUCE ELECTRICITY FOR MANUFACTURING OPERATIONS AND FOR THE TOWN OF RAINELLE. STEAM ENGINE IS A HAMILTON CORLISS. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  3. 5. DETAIL OF THE INSIDE ROBERTS AND SCHAEFER LOADING BOOM, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. DETAIL OF THE INSIDE ROBERTS AND SCHAEFER LOADING BOOM, WITH COUNTERWEIGHT (RIGHT), NOTE METAL CONVEYOR BELT (FOREGROUND) - Nuttallburg Mine Complex, Tipple, North side of New River, 2.7 miles upstream from Fayette Landing, Lookout, Fayette County, WV

  4. 50. INTERIOR VIEW OF PACKING LINE WHERE ALL THE NAIL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    50. INTERIOR VIEW OF PACKING LINE WHERE ALL THE NAIL BOXES ARE FORMED, FILLED WITH NAILS AND SEALED; NOTE THESE ARE FIFTY-POUND BOXES - LaBelle Iron Works, Thirtieth & Wood Streets, Wheeling, Ohio County, WV

  5. 77 FR 13263 - Withdrawal of Notice of Intent To Prepare an Environmental Impact Statement for the Upper Deckers...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-06

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF AGRICULTURE Natural Resources Conservation Service Withdrawal of Notice of Intent To Prepare an Environmental Impact Statement for the Upper Deckers Creek Watershed, Preston County, WV AGENCY: Natural Resources...

  6. 12. Credit WS. Basement of Mill, showing wooden flywheels to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Credit WS. Basement of Mill, showing wooden flywheels to water wheel and Fairbanks. Morse 20 hp, 350 rpm diesel engine, patented April 20, 1920. - Bunker Hill Mill, County Route 26, Bunker Hill, Berkeley County, WV

  7. 42. INTERIOR VIEW OF THE NAIL HARDENER USED TO HARDEN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    42. INTERIOR VIEW OF THE NAIL HARDENER USED TO HARDEN AND TEMPER THE NAILS; WEST TUBES IN FOREGRPUND AND DRAWBACK TUBE IN THE CENTER - LaBelle Iron Works, Thirtieth & Wood Streets, Wheeling, Ohio County, WV

  8. 47. INTERIOR VIEW, DETAIL OF CONVEYOR BELT SYSTEM SYSTEM WITH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    47. INTERIOR VIEW, DETAIL OF CONVEYOR BELT SYSTEM SYSTEM WITH BACK BELT DROPPING HARDENED NAILS ON THE FRONT BELT TO BE TEMPERED; MOTION STOPPED - LaBelle Iron Works, Thirtieth & Wood Streets, Wheeling, Ohio County, WV

  9. 45. INTERIOR VIEW SHOWING CONVEYOR BELT SYSTEM WHICH CONVEY THE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    45. INTERIOR VIEW SHOWING CONVEYOR BELT SYSTEM WHICH CONVEY THE HARDENED NAILS TO THE DRAWBACK TUBE FOR TEMPERING; MOTIONED STOPPED - LaBelle Iron Works, Thirtieth & Wood Streets, Wheeling, Ohio County, WV

  10. 11. VIEW LOOKING OUT UPPER LEVEL WINDOW OF WASH HOUSE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. VIEW LOOKING OUT UPPER LEVEL WINDOW OF WASH HOUSE SHOWING SLACK COAL STORAGE TANK - Kaymoor Coal Mine, South side of New River, upstream of New River Gorge Bridge, Fayetteville, Fayette County, WV

  11. 9. INTERIOR VIEW OF EYE PRESS AREA; TO LEFT IS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. INTERIOR VIEW OF EYE PRESS AREA; TO LEFT IS A TWO-BAY SLOTTED TYPE FURNACE, TO CENTER IS EYE PRESS, TO RIGHT IS CURCULAR SAW - Warwood Tool Company, Foot of Nineteenth Street, Wheeling, Ohio County, WV

  12. 1. NORTHWEST FRONT, SOUTHWEST SIDE (SPRING HOUSE IN FOREGROUND; BATH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. NORTHWEST FRONT, SOUTHWEST SIDE (SPRING HOUSE IN FOREGROUND; BATH HOUSE AT REAR) (4 x 5 negative; 5 x 7 print) - Salt Sulphur Springs, Spring House, U.S. Route 219, Salt Sulphur Springs, Monroe County, WV

  13. 2. SHOWING (LEFT TO RIGHT) CHAPEL, STORE BUILDING, SPRING HOUSE, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. SHOWING (LEFT TO RIGHT) CHAPEL, STORE BUILDING, SPRING HOUSE, AND BATH HOUSE, SOUTHEAST FACADES (4 x 5 negative; 5 x 7 print) - Salt Sulpher Springs, U.S. Route 219, Salt Sulphur Springs, Monroe County, WV

  14. 1. View southeast, farmhouse, wash house (266B), barn (266C), and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. View southeast, farmhouse, wash house (266-B), barn (266-C), and equipment shed (266-E) (left to right in photograph) - Abraham Cyrus Farmstead, Farmhouse, 3271 Cyrus Road (County Road 1/6), Cyrus, Wayne County, WV

  15. 1. View southeast, barn in setting, north side and west ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. View southeast, barn in setting, north side and west end exposed - Abraham Cyrus Farmstead, Barn, About 160 feet south-southwest of farmhouse at 3271 Cyrus Road (County Road 1/6), Cyrus, Wayne County, WV

  16. 15. View northeast, interior, second floor, central hallway (door to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. View northeast, interior, second floor, central hallway (door to northwest bedroom at left, doorway to second floor porch at right in photograph) - Abraham Cyrus Farmstead, Farmhouse, 3271 Cyrus Road (County Road 1/6), Cyrus, Wayne County, WV

  17. 1. GENERAL VIEW LOOKING EAST, SHOWING REINFORCED CONCRETE BRIDGE SPANNING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. GENERAL VIEW LOOKING EAST, SHOWING REINFORCED CONCRETE BRIDGE SPANNING SIMPSON CREEK. - Bridgeport Lamp Chimney Company, Simpson Creek Bridge, Spanning Simpson Creek, State Route 58 vicinity, Bridgeport, Harrison County, WV

  18. 2. GENERAL VIEW SHOWING SIMPSON CREEK BRIDGE WITH BRIDGEPORT LAMP ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. GENERAL VIEW SHOWING SIMPSON CREEK BRIDGE WITH BRIDGEPORT LAMP AND CHIMNEY COMPANY IN BACKGROUND. - Bridgeport Lamp Chimney Company, Simpson Creek Bridge, Spanning Simpson Creek, State Route 58 vicinity, Bridgeport, Harrison County, WV

  19. 35. INTERIOR VIEW, WHEELBRATORFRYE SHOT PEENER FOR REMOVAL OF RUST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    35. INTERIOR VIEW, WHEELBRATOR-FRYE SHOT PEENER FOR REMOVAL OF RUST AND SCALE; NOTE TOOLS ARE TUMBLED WITH BLASTED WITH LEAD SHOT TO CLEAN SURFACES - Warwood Tool Company, Foot of Nineteenth Street, Wheeling, Ohio County, WV

  20. 2. INTERIOR DETAIL VIEW OF CONNECTION BETWEEN CASTIRON ROOF TRUSSES ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. INTERIOR DETAIL VIEW OF CONNECTION BETWEEN CAST-IRON ROOF TRUSSES AND OCTAGONAL, CAST-IRON COLUMNS. - Baltimore & Ohio Railroad, Martinsburg East Roundhouse, East End of Race & Martin Streets, Martinsburg, Berkeley County, WV

  1. 8. DETAIL VIEW OF CASTIRON OCTAGONAL COLUMNS AND CASTIRON TRUSSES ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. DETAIL VIEW OF CAST-IRON OCTAGONAL COLUMNS AND CAST-IRON TRUSSES SUPPORTING SHED PORTION OF ROOF. - Baltimore & Ohio Railroad, Martinsburg West Roundhouse, East End of Race & Martin Streets, Martinsburg, Berkeley County, WV

  2. 14. INTERIOR VIEW OF FIREPLACE AND SURROUNDING WALL IN FIRST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. INTERIOR VIEW OF FIREPLACE AND SURROUNDING WALL IN FIRST FLOOR, NORTHWEST PARLOR, NORTH WALL, WITH SCALE (NOTE WALL STENCILING) - George W. Eckhart House, 810 Main Street, Wheeling, Ohio County, WV

  3. Direct injection of water vapor into the stratosphere by volcanic eruptions

    NASA Astrophysics Data System (ADS)

    Sioris, Christopher E.; Malo, Alain; McLinden, Chris A.; D'Amours, Real

    2016-07-01

    While theoretical studies show that water vapor (WV) can be directly injected into the stratosphere during a volcanic eruption, few observations of such a phenomenon exist. The Microwave Limb Sounder observed stratospheric injection of WV following the 2015 Calbuco eruption. Lower stratospheric mixing ratios exceeded 10 ppmv for a few days downwind of the injection location. Plume transport is confirmed by back trajectory modeling. Due to the short duration and limited spatial extent of the enhancement, climatic impact is expected to be negligible. This letter provides spatiotemporal analysis of a volcanogenic pulse of lower stratospheric WV as it dispersed. The inferred mass of stratospheric WV from this eruption of 2 megaton (Mt) and the rapid evanescence of the enhancement are similar to what has been observed for other eruptions, suggesting that injection by moderately explosive eruptions is not an effective mechanism for large-scale stratospheric hydration.

  4. 7. VIEW WEST, FERNOW EXPERIMENTAL FOREST WELL HOUSE, FERNOW EXPERIMENTAL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. VIEW WEST, FERNOW EXPERIMENTAL FOREST WELL HOUSE, FERNOW EXPERIMENTAL FOREST BUNKHOUSE, FERNOW EXPERIMENTAL FOREST GARAGE, AND FERNOW EXPERIMENTAL FOREST RESIDENCE. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  5. 27 CFR 9.111 - Kanawha River Valley.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...., dated 1958; (12) Sissonville, W. Va., dated 1958; (13) Romance, W. Va.,—Ky., dated 1957; (14) Kentuck, W... Johns Branch and Sugar Creek in the town of Romance, in Jackson County, WV. (Romance quadrangle) (8)...

  6. 27 CFR 9.111 - Kanawha River Valley.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...., dated 1958; (12) Sissonville, W. Va., dated 1958; (13) Romance, W. Va.,—Ky., dated 1957; (14) Kentuck, W... Johns Branch and Sugar Creek in the town of Romance, in Jackson County, WV. (Romance quadrangle) (8)...

  7. 27 CFR 9.111 - Kanawha River Valley.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...., dated 1958; (12) Sissonville, W. Va., dated 1958; (13) Romance, W. Va.,—Ky., dated 1957; (14) Kentuck, W... Johns Branch and Sugar Creek in the town of Romance, in Jackson County, WV. (Romance quadrangle) (8)...

  8. 27 CFR 9.111 - Kanawha River Valley.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...., dated 1958; (12) Sissonville, W. Va., dated 1958; (13) Romance, W. Va.,—Ky., dated 1957; (14) Kentuck, W... Johns Branch and Sugar Creek in the town of Romance, in Jackson County, WV. (Romance quadrangle) (8)...

  9. 27 CFR 9.111 - Kanawha River Valley.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...., dated 1958; (12) Sissonville, W. Va., dated 1958; (13) Romance, W. Va.,—Ky., dated 1957; (14) Kentuck, W... Johns Branch and Sugar Creek in the town of Romance, in Jackson County, WV. (Romance quadrangle) (8)...

  10. East yard, north elevation of car department tool house (converted ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    East yard, north elevation of car department tool house (converted from express car). - Chesapeake & Ohio Railroad, Thurmond Yards, East side New River, mouths of Arbuckle & Dunlop Circles, Thurmond, Fayette County, WV

  11. 44. VIEW THROUGH UPPER PORTION OF EAST TOWER ARCH, LOOKING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    44. VIEW THROUGH UPPER PORTION OF EAST TOWER ARCH, LOOKING WEST AT ROADWAY AND SUSPENSION CABLES. - Wheeling Suspension Bridge, Spanning East channel of Ohio River at U.S. Route 40, Wheeling, Ohio County, WV

  12. 53. Photocopy of photograph, c. 1946. GENERAL INTERIOR VIEW OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    53. Photocopy of photograph, c. 1946. GENERAL INTERIOR VIEW OF GENERATOR ROOM. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files, Dam No. 5 listing) - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  13. 60. Photocopy of photograph, no date. DETAIL OF SWITCHBOARD. (Courtesy ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    60. Photocopy of photograph, no date. DETAIL OF SWITCHBOARD. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files, Properties-Buildings and Equipment listing) - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  14. 61. Photocopy of photograph, c. 1949. DETAIL OF SWITCHBOARD WITH ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    61. Photocopy of photograph, c. 1949. DETAIL OF SWITCHBOARD WITH MODIFICATIONS. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files, Dam No. 5 listing) - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  15. 1. LOOKING WEST TOWARD OIL/CLEANING SUPPLY BUILDING (SIDING AND ROOF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. LOOKING WEST TOWARD OIL/CLEANING SUPPLY BUILDING (SIDING AND ROOF VISIBLE TO THE LEFT); GAS PUMP SHED IN CENTER (IN SHADOWS). - Standard Lime & Stone Quarry, Oil-Cleaning Supply Building, County Route 27, Millville, Jefferson County, WV

  16. 76 FR 53419 - Procurement List; Proposed Additions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-26

    ...): Lifetime Assistance, Inc., Rochester, NY. 57 Haddonfield Road, Cherry Hill, NJ 5218 Atlantic Avenue, Mays... (Subcontractor): PACE Enterprises of West Virginia, Inc., Star City, WV. 210 1st Street, SW., Roanoke, VA 1600...

  17. 75 FR 51812 - Radio Broadcasting Services; AM or FM Proposals To Change the Community of License

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-23

    ...., Station WGTI, Facility ID 173, BPH-20100804AAU, From DUCK, NC, To WINFALL, NC; LIGHT OF LIFE COMMUNITY, INC., Station WLOL-FM, Facility ID 172639, BMPED-20100722BOH, From MORGANTOWN, WV, To STAR CITY,...

  18. 1. LOOKING NORTH, SHOWING IODINE SPRING (FOREGROUND), SALT SULPHUR SPRING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. LOOKING NORTH, SHOWING IODINE SPRING (FOREGROUND), SALT SULPHUR SPRING (LEFT BACKGROUND), AND TWIN COTTAGES (UPPER RIGHT) (4 x 5 negative; 5 x 7 print) - Salt Sulpher Springs, U.S. Route 219, Salt Sulphur Springs, Monroe County, WV

  19. 21. William E. Barrett, Photographer, August 1975. EDGER SAWS FOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. William E. Barrett, Photographer, August 1975. EDGER SAWS FOR RIPPING BOARD TO VARIOUS WIDTHS. BLADES VISIBLE BEHIND ROLLERS. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  20. 19. William E. Barrett, Photographer, August 1975. LOWER BAND SAW ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. William E. Barrett, Photographer, August 1975. LOWER BAND SAW PULLEYS OF RIGHT-HAND MILL. DRIVE PULLEY IN BELOW TENSION PULLEY. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  1. 13. William E. Barrett, Photographer, August 1975. INTERIOR OF SAWMILL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. William E. Barrett, Photographer, August 1975. INTERIOR OF SAWMILL LOOKING EAST. LOGS FOR CENTER MILL ROLLED RIGHT TO CONVEYOR WHICH CARRIED THEM TO SECOND SLOPING DECK. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  2. 11. William E. Barrett, Photographer, August 1975. INTERIOR OF SAWMILL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    11. William E. Barrett, Photographer, August 1975. INTERIOR OF SAWMILL SHOWING STEAM CYLINDER AND PISTON ROD OF LEFT-HAND MILL (LEFT) AND HOUSING OF CENTER BANDSAW. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  3. 3. Photocopied August 1975 from The Evolution of Modern Band ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. Photocopied August 1975 from The Evolution of Modern Band Saw Mills for Sawing Logs, Dewitt Clinton Prescott, 1910. VIEW OF BAND SAW. *NOTE* 4'x 5' NEGATIVE - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  4. 4. Photocopied August 1975 from The Evolution of Modern Band ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Photocopied August 1975 from The Evolution of Modern Band Saw Mills for Sawing Logs, Dewitt Clinton Prescott, 1910. THREE-BLOCK LOG CARRIAGE. *NOTE* 4'x 5' NEGATIVE - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  5. 6. William E. Barrett, Photographer, 1975. GENERAL VIEW LOOKING EAST. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    6. William E. Barrett, Photographer, 1975. GENERAL VIEW LOOKING EAST. SAWMILL ON RIGHT. SECONDARY WOODWORKING SHOPS ON LEFT PARTIALLY DEMOLISHED. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  6. 20. William E. Barrett, Photographer, August 1975. INTERIOR OF SAWMILL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. William E. Barrett, Photographer, August 1975. INTERIOR OF SAWMILL LOOKING EAST. EDGER SAW AT LOWER LEFT, TRIMMERS AT RIGHT. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  7. 16. William E. Barrett, Photographer, August 1975. CENTER MILL (RIGHTHANDED) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. William E. Barrett, Photographer, August 1975. CENTER MILL (RIGHT-HANDED) WITH CARRIAGE TRACKS AND BANDSAW HOUSING INTACT. LOG CLAMPS ON THIS CARRIAGE WERE PNEUMATICALLY OPERATED. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  8. 8. William E. Barrett, Photographer, August 1975. LOG DOCK AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. William E. Barrett, Photographer, August 1975. LOG DOCK AND PARTIALLY DEMOLISHED JACKSLIP USED FOR HAULING LOGS UP TO SAWMILL. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  9. 14. INTERIOR VIEW, DETAIL OF TRIMMED FLASH; FLASH IS EXCESS ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. INTERIOR VIEW, DETAIL OF TRIMMED FLASH; FLASH IS EXCESS METAL EXTRUDED BETWEEN THE DIES USED TO FORGE THE BLADE END OF THE POST HOLE DIGGER - Warwood Tool Company, Foot of Nineteenth Street, Wheeling, Ohio County, WV

  10. 13. View South, showing the remaining pier footings for the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. View South, showing the remaining pier footings for the steam engine water tower for the Chesapeake and Ohio Railroad. - Cotton Hill Station Bridge, Spanning New River at State Route 16, Cotton Hill, Fayette County, WV

  11. TOWER, WEST ELEVATION, SHOWING CONNECTION PIPES FOR TURNOUTS 22 (FOREGROUND) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    TOWER, WEST ELEVATION, SHOWING CONNECTION PIPES FOR TURNOUTS 22 (FOREGROUND) AND 24. NOTE “LAZY JACK” TEMPERATURE COMPENSATOR IN FOREGROUND. - Baltimore & Ohio Railroad, Z Tower, State Route 46, Keyser, Mineral County, WV

  12. 9. TRANSMISSION GEARING FROM SPUR WHEEL (right) USED TO INCREASE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. TRANSMISSION GEARING FROM SPUR WHEEL (right) USED TO INCREASE REVOLUTIONS PER MINUTE William E. Barrett, photographer, 1973 - Thomas Shepherd's Grist Mill, High Street Vicinity, Shepherdstown, Jefferson County, WV

  13. 46. William E. Barrett, Photographer, August 1975. INTERIOR OF EAST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    46. William E. Barrett, Photographer, August 1975. INTERIOR OF EAST ADDITION TO POWERHOUSE SHOWING GENERATING UNITS (STEAM TURBINE) ADDED. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  14. 40 CFR 81.349 - West Virginia.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... affecting § 81.349 see the List of CFR Sections Affected which appears in the Finding Aids section of the.... Huntington-Ashland, WV-KY-OH: Cabell County Nonattainment. Mason County (part) Nonattainment. Graham...

  15. 8. VIEW EAST, CIVILIAN CONSERVATION CORPS CAMP PARSONS GARAGE, MODERN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. VIEW EAST, CIVILIAN CONSERVATION CORPS CAMP PARSONS GARAGE, MODERN SHED, CIVILIAN CONSERVATION CORPS CAMP PARSONS BLACKSMITH SHOP, AND MODERN SHED. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  16. 30 CFR 20.3 - Application procedures and requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC MINE LAMPS OTHER THAN STANDARD CAP LAMPS § 20.3... Certification Center, 765 Technology Drive, Triadelphia, WV 26059, together with the required drawings,...

  17. 30 CFR 19.3 - Application procedures and requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC CAP LAMPS § 19.3 Application procedures and requirements... Certification Center, 765 Technology Drive, Triadelphia, WV 26059, together with the required drawings,...

  18. 30 CFR 19.13 - Instructions for handling future changes in lamp design.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... LABOR TESTING, EVALUATION, AND APPROVAL OF MINING PRODUCTS ELECTRIC CAP LAMPS § 19.13 Instructions for..., Approval and Certification Center, 765 Technology Drive, Triadelphia, WV 26059, requesting an extension...

  19. 77 FR 64356 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-19

    ... and Green Energy Initiatives LLC. 81,880A Mountain State Carbon, LLC, Follansbee, WV........ August 7.......... Casualty--Renewable Energy Division. The investigation revealed that the criteria under paragraphs...

  20. DETAIL OF BEEHIVE COKE OVEN DOOR, LOOKING NORTH; NOTE FIREBRICK ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL OF BEEHIVE COKE OVEN DOOR, LOOKING NORTH; NOTE FIRE-BRICK ARCH AND IRON JAMB AND SILL - Nuttallburg Mine Complex, Coke Ovens, North side of New River, 2.7 miles upstream from Fayette Landing, Lookout, Fayette County, WV

  1. 42 CFR 84.136 - Facepieces, hoods, and helmets; eyepieces; minimum requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Assurance Branch, 1095 Willowdale Road, Morgantown, WV 26505-2888. (c)(1) The eyepieces of AE, BE, and CE type supplied-air respirators shall be shielded by plastic, glass, woven wire, sheet metal, or...

  2. 75 FR 52978 - Agency Information Collection Activities: Proposed Collection; Comments Requested

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-30

    ... of Alcohol, Tobacco, Firearms and Explosives Agency Information Collection Activities: Proposed... Federal firearms license. The Department of Justice (DOJ), Bureau of Alcohol, Tobacco, Firearms and... Firearms Licensing Center, 244 Needy Road, Martinsburg, WV 20226. Written comments and suggestions from...

  3. 75 FR 52977 - Agency Information Collection Activities: Proposed Collection; Comments Requested

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-30

    ... of Alcohol, Tobacco, Firearms and Explosives Agency Information Collection Activities: Proposed... Alcohol, Tobacco, Firearms and Explosives (ATF), will be submitting the following information collection... Desiree Winger, Firearms and Explosives Imports Branch, 244 Needy Road, Martinsburg, WV 25405....

  4. 61. FAN HOUSE BUILT DURING LOW MOOR ERA; PEDESTALS ON ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    61. FAN HOUSE BUILT DURING LOW MOOR ERA; PEDESTALS ON WHICH FAN RESTED IS IN FOREGROUND, LOOKING SOUTH - Kaymoor Coal Mine, South side of New River, upstream of New River Gorge Bridge, Fayetteville, Fayette County, WV

  5. View of Harpers Ferry, station behind trees in lower right. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of Harpers Ferry, station behind trees in lower right. Taken from Maryland Heights Ridge from the east. - Baltimore & Ohio Railroad, Harpers Ferry Station, Potomac Street, Harpers Ferry, Jefferson County, WV

  6. 4. EASTBOUND VIEW. NORTH TRACK WAITING STATION ON LEFT. STATION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. EASTBOUND VIEW. NORTH TRACK WAITING STATION ON LEFT. STATION ON RIGHT. NOTE TUNNEL IN BACKGROUND. - Baltimore & Ohio Railroad, Harpers Ferry Station, Potomac Street, Harpers Ferry, Jefferson County, WV

  7. 13. VIEW FROM POTOMAC RIVER BRIDGE PLATFORM WEST TOWARDS STATION. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. VIEW FROM POTOMAC RIVER BRIDGE PLATFORM WEST TOWARDS STATION. HARPERS FERRY DEPOT IS ON LEFT, NORTH TRACK WAITING STATION IS ON RIGHT. - Baltimore & Ohio Railroad, Harpers Ferry Station, Potomac Street, Harpers Ferry, Jefferson County, WV

  8. View of Harpers Ferry, station to right at end of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of Harpers Ferry, station to right at end of CSX Railroad Bridge. Taken from Maryland Heights Ridge from the east. - Baltimore & Ohio Railroad, Harpers Ferry Station, Potomac Street, Harpers Ferry, Jefferson County, WV

  9. 30. Credit JTL. Second floor, view of Eureka Milling Separator, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    30. Credit JTL. Second floor, view of Eureka Milling Separator, by S. Howes Co., (Silver Creek, NY); separated out undersired grains and impurities prior to milling. - Bunker Hill Mill, County Route 26, Bunker Hill, Berkeley County, WV

  10. 35. Credit JTL. Third floor, side view of Monitor Dustless ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    35. Credit JTL. Third floor, side view of Monitor Dustless Receiving Separator, by Huntley, Cranson and Hammond, (Silver Creek NY) capacity of 100 barrels/day. - Bunker Hill Mill, County Route 26, Bunker Hill, Berkeley County, WV

  11. 14. FLOODED POWER HOUSE FOUNDATION EXCAVATION BEING PUMPED OUT. NOTE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. FLOODED POWER HOUSE FOUNDATION EXCAVATION BEING PUMPED OUT. NOTE KEYS IN FOREBAY ABUTMENT TO INTERLOCK WITH POWER HOUSE FOUNDATION, March 1918. - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  12. 9. (5 X 7 enlargement from 4 X 5 negative) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. (5 X 7 enlargement from 4 X 5 negative) FIRST FLOOR, WINDOW MOLDING ON SOUTH WALL LOOKING SOUTH - Sites Homestead, Monongahela National Forest (Tract 390) East of Route 28, Seneca Rocks, Pendleton County, WV

  13. 78 FR 2394 - Columbia Gas Transmission, LLC; Notice of Request Under Blanket Authorization

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-11

    ... its Seneca Compressor Station located in Pendleton County, WV. Columbia also seeks authorization to abandon by removal an existing 6,200 horsepower compressor unit at its Seneca Compressor Station....

  14. 42. Credit TR. Dam No. 4 after 1936 flood; break ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    42. Credit TR. Dam No. 4 after 1936 flood; break as seen from upstream. Note original timber cribbing to left. Photo c. 1936. - Dam No. 4 Hydroelectric Plant, Potomac River, Martinsburg, Berkeley County, WV

  15. 44. Credit TR. Dam No. 4 after 1936 flood from ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    44. Credit TR. Dam No. 4 after 1936 flood from downstream showing break closed and installation of new concrete cap piece under way. Photo c. 1936. - Dam No. 4 Hydroelectric Plant, Potomac River, Martinsburg, Berkeley County, WV

  16. 4. Photocopied 1974 from Souvenir Album, Leighton and Frey Souvenir ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Photocopied 1974 from Souvenir Album, Leighton and Frey Souvenir View Company, (n.d.). THREE VIEWS OF BALTIMORE & OHIO RAILROAD. - Baltimore & Ohio Railroad, Tray Run Viaduct, Spanning Tray Run, Rowlesburg, Preston County, WV

  17. 15. STONE BURR MILL PROBABLY USED FOR GRINDING FEED. ONLY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. STONE BURR MILL PROBABLY USED FOR GRINDING FEED. ONLY REMAINING MILL MACHINERY William E. Barrett, photographer, 1973 - Thomas Shepherd's Grist Mill, High Street Vicinity, Shepherdstown, Jefferson County, WV

  18. 40. William E. Barrett, Photographer, August 1975. ROOF OF POWERHOUSE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    40. William E. Barrett, Photographer, August 1975. ROOF OF POWERHOUSE SHOWING HOPPERS FOR SAWDUST USED TO FIRE STEAM BOILERS. DUCTS AT LEFT LEAD FROM PLANNING MILL AND OTHER MANUFACTURING OPERATIONS. - Meadow River Lumber Company, Highway 60, Rainelle, Greenbrier County, WV

  19. View of steam powered air compressor in boiler house. Gas ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View of steam powered air compressor in boiler house. Gas engine powered electric generators are visible in far left background. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  20. Detail exterior view looking northwest showing field gas cleaner in ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail exterior view looking northwest showing field gas cleaner in the center. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  1. Interior view of boiler house looking south. Boiler units are ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Interior view of boiler house looking south. Boiler units are on left. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  2. Detail view of steam chest for low pressure stage of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of steam chest for low pressure stage of unit 40. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  3. Detail view of unit 43 with high pressure stage compressor ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of unit 43 with high pressure stage compressor in left foreground. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  4. Detail view of gauges that record pressure of gas coming ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of gauges that record pressure of gas coming into the engine house. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  5. Detail view of feedwater pump (below) and preheater tanks (above) ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of feedwater pump (below) and preheater tanks (above) in boiler house. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  6. General exterior view looking north. Boiler house is center/left. Engine ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General exterior view looking north. Boiler house is center/left. Engine house is center right. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  7. Detail view of oil container designed as part of lubricating ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of oil container designed as part of lubricating system for unit 43. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  8. Detail view of condensor located below the floor level of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of condensor located below the floor level of the pumphouse. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  9. Detail view of steam chest and valve mechanisms for high ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of steam chest and valve mechanisms for high pressure stage of unit 40. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  10. Detail view of valve mechanisms and goverenor on high pressure ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of valve mechanisms and goverenor on high pressure stage engine of unit 43. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  11. Exterior view of boiler house looking southwest with steam exhaust ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Exterior view of boiler house looking southwest with steam exhaust vents in foreground. Engine house is on left. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  12. Exterior view looking north/northwest showing water intake from Little Kanawha ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Exterior view looking north/northwest showing water intake from Little Kanawha River on right. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  13. Detail exterior view looking southwest of gas cooling system. Engine ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail exterior view looking southwest of gas cooling system. Engine house is shown in right background. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  14. General view looking north showing boilers with units 47 and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view looking north showing boilers with units 47 and 48 in right foreground. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  15. General interior view of pumphouse looking southwest. Compressor unit 40 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General interior view of pumphouse looking southwest. Compressor unit 40 is in foreground. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  16. DETAIL VIEW OF OIL CONTAINER DESIGNED AS PART OF LUBRICATING ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL VIEW OF OIL CONTAINER DESIGNED AS PART OF LUBRICATING SYSTEM FOR UNIT #3. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  17. Detail view of wrenches used in maintenance of engines and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of wrenches used in maintenance of engines and compressors. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  18. Exterior view looking northwest with construction facilities of "new" pumping ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Exterior view looking northwest with construction facilities of "new" pumping station in foreground. Doug Hine is man in picture. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  19. Detail view of gauges that record pressure of gas leaving ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of gauges that record pressure of gas leaving the engine house. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  20. Detail view of lubricating oil pumps used in maintenance of ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of lubricating oil pumps used in maintenance of the engines and compressors. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  1. DETAIL VIEW OF STEAM CHEST FOR LOW PRESSURE STAGE ENGINE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL VIEW OF STEAM CHEST FOR LOW PRESSURE STAGE ENGINE OF UNIT #3. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  2. Detail view of steam chest for low pressure stage engine ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of steam chest for low pressure stage engine of unit 43. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  3. DETAIL VIEW OF UNIT #3 WITH HIGH PRESSURE STAGE COMPRESSOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    DETAIL VIEW OF UNIT #3 WITH HIGH PRESSURE STAGE COMPRESSOR IN LEFT FOREGROUND. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  4. Detail exterior view looking north showing piping system adjacent to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail exterior view looking north showing piping system adjacent to engine house. Gas cooling system is on far right. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  5. 75 FR 71462 - Investigations Regarding Certifications of Eligibility To Apply for Worker Adjustment Assistance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-23

    ... Cranberry Resources, LLC Beckley, WV........ 11/01/10 10/25/10 (Company). 74806 Cranberry Hardwoods, Beckley..., TN.. 11/05/10 10/25/10 Company (Company). 74826 Cranberry Lumber Company Newport, OH...........

  6. Environmental perspective facing south showing chicken house, tractor shed, and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Environmental perspective facing south showing chicken house, tractor shed, and homestead - Norris Farm, .5 mile west of County Road 857 & .25 mile east of County Road 88/1, Cheat Neck, Monongalia County, WV

  7. North and east elevations of tractor shed facing southwest ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    North and east elevations of tractor shed facing southwest - Norris Farm, Tractor Shed-Combine Barn, .5 mile west of County Road 857 & .25 mile east of County Road 88/1, Cheat Neck, Monongalia County, WV

  8. 7. William E. Barrett, Photographer, 1974. SKEWED VIEW SHOWING CHEAT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. William E. Barrett, Photographer, 1974. SKEWED VIEW SHOWING CHEAT RIVER VALLEY, REMAINS OF 1887 PIER AND c. 1900 MASONRY ARCHES. - Baltimore & Ohio Railroad, Tray Run Viaduct, Spanning Tray Run, Rowlesburg, Preston County, WV

  9. 8. Environmental view facing northwest showing pond in relationship to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. Environmental view facing northwest showing pond in relationship to house - John Bly House, East side of County Road 857, just north of intersection with Quarry Run Road, Cheat Neck, Monongalia County, WV

  10. South and west elevations of tractor shed facing northeast ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    South and west elevations of tractor shed facing northeast - Norris Farm, Tractor Shed-Combine Barn, .5 mile west of County Road 857 & .25 mile east of County Road 88/1, Cheat Neck, Monongalia County, WV

  11. 1. Photocopied 1974 from Album of Baltimore and Ohio Railroad, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Photocopied 1974 from Album of Baltimore and Ohio Railroad, Witteman Brothers, Smithsonian Institution, 1882. WOODCUT ILLUSTRATION OF TRESTLE WORK, CHEAT RIVER GORGE. - Baltimore & Ohio Railroad, Tray Run Viaduct, Spanning Tray Run, Rowlesburg, Preston County, WV

  12. 30 CFR 36.6 - Application procedures and requirements.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., EVALUATION, AND APPROVAL OF MINING PRODUCTS APPROVAL REQUIREMENTS FOR PERMISSIBLE MOBILE DIESEL-POWERED... and Certification Center, 765 Technology Drive, Triadelphia, WV 26059. Fees calculated in accordance... that MSHA considers necessary for certification of the particular mobile diesel-powered...

  13. 30 CFR 36.6 - Application procedures and requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., EVALUATION, AND APPROVAL OF MINING PRODUCTS APPROVAL REQUIREMENTS FOR PERMISSIBLE MOBILE DIESEL-POWERED... and Certification Center, 765 Technology Drive, Triadelphia, WV 26059. Fees calculated in accordance... that MSHA considers necessary for certification of the particular mobile diesel-powered...

  14. 30 CFR 36.6 - Application procedures and requirements.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., EVALUATION, AND APPROVAL OF MINING PRODUCTS APPROVAL REQUIREMENTS FOR PERMISSIBLE MOBILE DIESEL-POWERED... and Certification Center, 765 Technology Drive, Triadelphia, WV 26059. Fees calculated in accordance... that MSHA considers necessary for certification of the particular mobile diesel-powered...

  15. 77 FR 66634 - Agency Information Collection Activities: Proposed Collection; Comments Requested: Application To...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-06

    ... of Alcohol, Tobacco, Firearms and Explosives Agency Information Collection Activities: Proposed... Explosives (ATF), will be submitting the following information collection request to the Office of Management... Explosives Imports Branch, 244 Needy Road, Martinsburg, WV 25405. Written comments and suggestions from...

  16. 33 CFR 160.210 - Methods for submitting an NOA.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... NVMC, United States Coast Guard, 408 Coast Guard Drive, Kearneysville, WV 25430, by: (1) Electronic...) in Table 160.206 must be submitted electronically to the USCS Sea AMS by one of the following...

  17. 2. Photocopied 1972 from Ecole imperiale des ponts et chaussees, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Photocopied 1972 from Ecole imperiale des ponts et chaussees, Collection de Dessins Distribues aus eleves, (n.d. and no place), ORIGINAL FINK TRUSS BRIDGE, 1852. - Baltimore & Ohio Railroad, Fairmont Bridge, Spanning Monongahela River, Fairmont, Marion County, WV

  18. 10. INTERIOR VIEW OF EYE PRESS AREA, SAME AS ABOVE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    10. INTERIOR VIEW OF EYE PRESS AREA, SAME AS ABOVE WITH MEN AT WORK: CRAIG TSCHAPPAT, HEATER; JEFF MILLER, OPERATOR; JOHN TOTH, SAWMAN - Warwood Tool Company, Foot of Nineteenth Street, Wheeling, Ohio County, WV

  19. View southeast, general view, barn at left Woods Homestead, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View southeast, general view, barn at left - Woods Homestead, County Route 12 on north side of North Fork of Hughes River, 2.2 miles north & east of Goose Run Road intersection, Harrisville, Ritchie County, WV

  20. View east, barn, west elevation Woods Homestead, Barn, County ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View east, barn, west elevation - Woods Homestead, Barn, County Route 12 on north side of North Fork of Hughes River, 2.2 miles north & east of Goose Run Road intersection, Harrisville, Ritchie County, WV

  1. View west, interior, detail of joinery Woods Homestead, Barn, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View west, interior, detail of joinery - Woods Homestead, Barn, County Route 12 on north side of North Fork of Hughes River, 2.2 miles north & east of Goose Run Road intersection, Harrisville, Ritchie County, WV

  2. View north, barn, south elevation Woods Homestead, Barn, County ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View north, barn, south elevation - Woods Homestead, Barn, County Route 12 on north side of North Fork of Hughes River, 2.2 miles north & east of Goose Run Road intersection, Harrisville, Ritchie County, WV

  3. View west, barn, east elevation Woods Homestead, Barn, County ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View west, barn, east elevation - Woods Homestead, Barn, County Route 12 on north side of North Fork of Hughes River, 2.2 miles north & east of Goose Run Road intersection, Harrisville, Ritchie County, WV

  4. View south, barn, north elevation Woods Homestead, Barn, County ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View south, barn, north elevation - Woods Homestead, Barn, County Route 12 on north side of North Fork of Hughes River, 2.2 miles north & east of Goose Run Road intersection, Harrisville, Ritchie County, WV

  5. 14. Credit PED. Downstream elevation, near completion, showing tail race ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Credit PED. Downstream elevation, near completion, showing tail race and trestle used to carry excavated rock and construction materials across tail race. Photo c. 1909. - Dam No. 4 Hydroelectric Plant, Potomac River, Martinsburg, Berkeley County, WV

  6. 32. Credit JTL. Exterior transformer bank; note lightning arrestors removed ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    32. Credit JTL. Exterior transformer bank; note lightning arrestors removed from pad and smaller arrestors installed on transformers and in area near air switches. - Dam No. 4 Hydroelectric Plant, Potomac River, Martinsburg, Berkeley County, WV

  7. 36. POT IN OVEN NO. 9. MEASURING STICK IS USED ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    36. POT IN OVEN NO. 9. MEASURING STICK IS USED TO MAKE SURE THAT POT IS ALL THE WAY IN. - Seneca Glass Company Factory, Beechurst Avenue between Sixth & Eighth Streets, Morgantown, Monongalia County, WV

  8. 2. DETAIL OF INVERTED MINE CARS, LOOKING SOUTHWEST; NOTE SHORT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. DETAIL OF INVERTED MINE CARS, LOOKING SOUTHWEST; NOTE SHORT WHEEL BASE NEEDED FOR DUMPING CONTENTS - Nuttallburg Mine Complex, Main Mine, North side of New River, 2.7 miles upstream from Fayette Landing, Lookout, Fayette County, WV

  9. 21. Credit WS. Ground floor, Midget Marvel milling machine, a ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. Credit WS. Ground floor, Midget Marvel milling machine, a 25 barrel day machine by the Anglo American Mill Co. (Owensboro, KY), without covers, exposing rollers and sifters. - Bunker Hill Mill, County Route 26, Bunker Hill, Berkeley County, WV

  10. Corynebacterium marinum sp. nov. isolated from coastal sediment in Qingdao, China

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A taxonomic study was performed on strain D7015T, which was isolated from coastal sediment close to a coal-fired power station in Qingdao, China. D7015T comprised Gram-positive, non-motile diphtheroid rods, which grew in 0-10 % (w/v) NaCl and 4-37°C, with optimum growth at 1% (w/v) NaCl and 30-32°C...

  11. 24. Photo copy of photograph, (original in Forest Service Office, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    24. Photo copy of photograph, (original in Forest Service Office, Elkins, WV, photo #397508, 'Women weeding in the one-year old red spruce seedlings at the Parsons Nursery at Parsons, W. Va. Women are used for weeding here because of the dexterity of their hands. They are paid 40 cents an hour'), B. W. Muir, 1940. VIEW NORTHEAST, PACKING BUILDING IN BACKGROUND, WOMEN WEEDING. - Parsons Nursery, South side of U.S. Route 219, Parsons, Tucker County, WV

  12. Weak measurements measure probability amplitudes (and very little else)

    NASA Astrophysics Data System (ADS)

    Sokolovski, D.

    2016-04-01

    Conventional quantum mechanics describes a pre- and post-selected system in terms of virtual (Feynman) paths via which the final state can be reached. In the absence of probabilities, a weak measurement (WM) determines the probability amplitudes for the paths involved. The weak values (WV) can be identified with these amplitudes, or their linear combinations. This allows us to explain the "unusual" properties of the WV, and avoid the "paradoxes" often associated with the WM.

  13. Development and evaluation of a new growth medium for Helicobacter pylori.

    PubMed

    Sasidharan, Sreenivasan; Uyub, Abdul M

    2009-06-01

    The present study was aimed at modifying the original formulation of Commercial Eugon agar (CEA) to develop a new H. pylori growth medium. Initial studies were carried out to determine the number of H. pylori colonies recovered on in-house H. pylori agar (IHPA), IHPA without L-cysteine and sodium sulfite (IHPA-NC), IHPA without L-cysteine (IHPA-C), IHPA without sodium sulfite (IHPA-N) and CEA as the control. Significant differences (P < 0.001) in the number of colonies recovered were observed between IHPA-N, IHPA-NC and IHPA-C. Incorporation of sodium sulfite decreased the number of colonies recovered, indicating that sodium sulfite was inhibitory to H. pylori growth. Removal of L-cysteine reduced the number of colonies recovered, suggesting that L-cysteine is necessary for the growth of H. pylori. In the subsequent study, incorporation of K(2)HPO(4) further increased the number of colonies recovered compared with IHPA-N (P < 0.001), and 0.25% (w/v) of K(2)HPO(4) yielded the highest numbers of colonies (P < or = 0.04). Finally, thirty other H. pylori clinical isolates were evaluated for their growth in the IHPAP-N, a new medium consisting of 1.5% (w/v) pepticase, 0.5% (w/v) peptone, 0.4% (w/v) sodium chloride, 0.03% (w/v) L-cysteine, 0.55% (w/v) dextrose, 0.25% (w/v) K(2)HPO(4) and 1.5% (w/v) agar. The number of colonies recovered in IHPAP-N was significantly (P < 0.005) higher than that of CEA. IHPAP-N with 0.25% K(2)HPO(4) and without sodium sulfite were adequate solid media for the growth of H. pylori.

  14. Flavobacterium faecale sp. nov., an agarase-producing species isolated from stools of Antarctic penguins.

    PubMed

    Kim, Jin Ho; Choi, Bo Hyun; Jo, Minho; Kim, Sun Chang; Lee, Pyung Cheon

    2014-08-01

    Taxonomic studies were performed on an agarase-producing strain, designated WV33(T), isolated from faeces of Antarctic penguins. Cells of strain WV33(T) were Gram-staining-negative, strictly aerobic, orange and rod-shaped. Strain WV33(T) displayed agarase activity and was able to utilize galactose as a sole carbon source. 16S rRNA gene sequence analysis revealed that strain WV33(T) was closely related to Flavobacterium algicola TC2(T) (98.0% similarity), F. frigidarium ATCC 700810(T) (96.9%) and F. frigoris LMG 21922(T) (96.1%). The predominant cellular fatty acids were iso-C(15 : 1) G, iso-C(15 : 0), C(15 : 0), C(16 : 0) and summed feature 3 (comprising iso-C(15 : 0) 2-OH and/or C(16 : 1)ω7c). Menaquinone 6 (MK-6) was the sole quinone identified, and the major pigment was zeaxanthin. The major polar lipid was phosphatidylethanolamine. DNA-DNA relatedness of strain WV33(T) with respect to its closest phylogenetic neighbours was 25% for F. algicola NBRC 102673(T), 23% for F. frigidarium DSM 17623(T) and 21% for F. frigoris DSM 15719(T). The DNA G+C content of strain WV33(T) was 37±0.6 mol%. Based on the phenotypic, chemotaxonomic and phylogenetic data, strain WV33(T) is concluded to represent a novel species of the genus Flavobacterium, for which the name Flavobacterium faecale sp. nov. is proposed. The type strain is WV33(T) ( = KCTC 32457(T) = CECT 8384(T)).

  15. Influence of immobilization parameters on growth and lactic acid production by Streptococcus thermophilus and Lactobacillus bulgaricus co-immobilized in calcium alginate gel beads.

    PubMed

    Garbayo, I; Vílchez, C; Vega, J M; Nava-Saucedo, J E; Barbotin, J N

    2004-12-01

    Streptococcus thermophilus and Lactobacillus bulgaricus were co-immobilized in different systems with varying calcium (0.1-1.5 M) and alginate (1-2%, w/v) concentrations. Highest lactic acid production was 35 g l(-1) when both bacteria were in high viscosity beads (1%, w/v alginate) hardened in 0.1 M CaCl2 . The gel bead composition affected size and distribution of entrapped lactic acid bacteria.

  16. Mast cells contribute to fibrin deposition in reverse passive Arthus reaction in mouse skin.

    PubMed

    Ramos, B F; Zhang, Y; Jakschik, B A

    1992-09-01

    The activation of the clotting system is an important process during inflammation to contain the injury and initiate tissue repair. In the present study, we investigated the effect of mast cells on fibrin deposition in reverse passive Arthus reaction in mast cell-deficient WBB6F1-W/Wv(W/Wv) and control WBB6F1-(+)/+(+/+) mice, that were given 125I-labeled fibrogen intravenousty. An antibody dose-dependent increase in radioactivity was observed in the challenged skin sites. Sequential water and urea extractions characterized the radioiodinated fibrinogen derivatives present in the tissue. The radioactivity found in the various fractions of the stimulated samples from +/+ was 2-10-fold higher than that in specimens from W/Wv mice. The greatest difference was observed in the urea-insoluble pellet (cross-linked fibrin and its early degradation products). Reconstitution of W/Wv mice with mast cells augmented the response to levels similar to those in +/+ mice. Pretreatment with the antihistamine pyrilamine blocked the accumulation of 125I-labeled fibrinogen and its derivatives by approximately 70% in +/+ but not in W/Wv mice. Inhibition of leukotriene synthesis by A-63162 markedly decreased the accumulation of iodinated fibrinogen in both +/+ and W/Wv mice. The data suggest that mast cells and their vasoactive mediator histamine contribute to the exudation of clotting factors, which results in fibrin deposition and that mast cells also enhance fibrin cross-linkage.

  17. Generation and survival of midbrain dopaminergic neurons in weaver mice.

    PubMed

    Martí, Joaquín; Santa-Cruz, M C; Bayer, Shirley A; Ghetti, Bernardino; Hervás, José P

    2007-08-01

    Generation and survival of midbrain dopaminergic (DA) neurons were investigated using tyrosine hydroxylase (TH) immunocytochemistry combined with tritiated thymidine autoradiography at appropriate anatomical levels throughout the anteroposterior (A/P) axes of the substantia nigra pars compacta (SNc) and the ventral tegmental area (VTA). The wild-type (+/+) and homozygous weaver (wv/wv) mice used here were the offspring of pregnant dams injected with the radioactive precursor when the mesencephalic neurons were being produced (gestational days 11-15). Data reveal that, at postnatal day 90, depletion of TH-stained cells in the wv/wv presented an A/P pattern of increasing severity and, therefore, the DA cells located in posterior parts of the SNc or the VTA appear to be more vulnerable than the settled anterior neurons. When the time of neuron origin is inferred for each level of these cell groups, it is found that the neurogenesis span is similar for both experimental groups, although significant deficits in the frequency of wv/wv late-generated neurons were observed in any level considered. On the other hand, it has been found that TH-positive neurons were settled along the extent of the SNc and the VTA following precise and differential neurogenetic gradients. Thus, the acute rostrocaudal increase in the proportion of late-generated neurons detected in both+/+DA-cell groups is disturbed in the weaver homozygotes due to the indicated A/P depletion.

  18. Optimization of culture medium compositions for gellan gum production by a halobacterium Sphingomonas paucimobilis.

    PubMed

    Zhang, Jun; Dong, Ya-chen; Fan, Lin-lin; Jiao, Zhi-hua; Chen, Qi-he

    2015-01-22

    The effect of culture medium compositions on gellan gum production produced by fermentation with a halobacterium Sphingomonas paucimobilis QHZJUJW CGMCC2428 was studied. In this work, a fractional factorial design was applied to investigate the main factors that affected gellan gum production by S. paucimobilis QHZJUJW CGMCC2428. Sucrose was the best carbon source for gellan gum and peptone displayed better inducing effect. Central composite design and response surface methodology were adopted to derive a statistical model for optimizing submerged culture medium composition. These experimental results showed that the optimum culture medium for producing gellan gum was composed of 40.00 (w/v) sucrose, 3.00% peptone (w/v), MgSO4 (w/v), 9.20% KH2PO4 (w/v), 7.50% Na2HPO4 (w/v), 4.30% K2SO4 (w/v), pH 6.8-7.0. The maximal gellan gum was 19.89±0.68 g/L, which was agreed closely with the predicated value (20.12 g/L). After incubated for 72 h under the optimized culture medium in 5-L bioreactor, the gellan gum fermentation reached about 19.90±0.68 g/L, which was higher than that in the initial cultivation medium.

  19. Stratigraphy and magnetic polarity of the high terrace remnants in the upper Ohio and Monongahela Rivers in West Virginia, Pennsylvania, and Ohio

    USGS Publications Warehouse

    Jacobson, R.B.; Elston, D.P.; Heaton, John W.

    1988-01-01

    A synthesis of previous work and new data on the stratigraphy of high terraces of the Ohio and Monongahela Rivers upstream from Parkersburg, West Virginia, indicates a correspondence between terrace histories in the ancient Teays and Pittsburgh drainage basins. Four terraces are identified in each. Sediments of the lower three alluvial and slackwater terraces, correlated with Illinoian, early Wisconsin, and late Wisconsin glacial deposits, have been traced along the modern Ohio River through the former divide between the Teays and Pittsburgh basins. Sediments in the fourth terrace, the highest well-defined terrace in each basin, were deposited in two ice-dammed lakes, separated by a divide near New Martinsville, West Virginia. Some deposits of the highest slackwater terrace in both the Teays and Pittsburgh basins have reversed remanent magnetic polarity. This, and the stratigraphic succession in the two basins, suggests that both were ponded during the same glaciation. Reversed polarity in these terrace sediments restricts the age of the first ice-damming event for which stratigraphic evidence is well-preserved to a pre-Illinoian, early Pleistocene glaciation prior to 788,000 yr ago. In contrast, slackwater sediments in the Monongahela River valley, upstream from an outwash gravel dam at the Allegheny-Monongahela confluence, have normal remanent magnetic polarity, corroborating correlation with an Illinoian ponding event. ?? 1988.

  20. Enhanced mucosal permeability and nitric oxide synthase activity in jejunum of mast cell deficient mice

    PubMed Central

    Komatsu, S; Grisham, M; Russell, J; Granger, D

    1997-01-01

    Background—Recent reports have described a modulating influence of nitric oxide (NO) on intestinal mucosal permeability and have implicated a role for mast cells in this NO mediated process. 
Aims—To assess further the contribution of mast cells to the mucosal permeability changes elicited by the NO synthase (NOS) inhibitor NG-nitro-L-arginine methylester (L-NAME), using mast cell deficient (W/WV) and mast cell replete mice (+/+). 
Methods—Chromium-51 EDTA clearance (from blood to jejunal lumen), jejunal NOS and myeloperoxidase (MPO) activities, and plasma nitrate/nitrite levels were monitored. 
Results—The increased EDTA clearance elicited by intraluminal L-NAME in W/WV mice (4.4-fold) was significantly greater than the response observed in control (+/+) mice (1.8-fold). The exacerbated response in W/Wv mice was greatly attenuated by pretreatment with either dexamethasone (1.3-fold) or the selective inducible NOS inhibitor, aminoguanidine (1.4-fold), and partially attenuated by the mast cell stabiliser, lodoxamide (2.9-fold). Jejunal inducible NOS activity was significantly higher in W/WV than in +/+ mice, while jejunal MPO was lower in W/WV mice than in +/+ mice, suggesting that the higher inducible NOS in W/WV does not result from the recruitment of inflammatory cells into the gut. The higher inducible NOS activity in the jejunum of W/WV was significantly reduced by dexamethasone treatment. 
Conclusions—Our results suggest that mast cells normally serve to inhibit inducible NOS activity tonically in the gut and that inhibitors of NOS elicit a larger permeability response when this tonic inhibitory influence is released by mast cell depletion. 

 Keywords: aminoguanidine; c-kit; dexamethasone; epithelium; neutrophils PMID:9414970

  1. Histamine from Brain Resident MAST Cells Promotes Wakefulness and Modulates Behavioral States

    PubMed Central

    Chikahisa, Sachiko; Kodama, Tohru; Soya, Atsushi; Sagawa, Yohei; Ishimaru, Yuji; Séi, Hiroyoshi; Nishino, Seiji

    2013-01-01

    Mast cell activation and degranulation can result in the release of various chemical mediators, such as histamine and cytokines, which significantly affect sleep. Mast cells also exist in the central nervous system (CNS). Since up to 50% of histamine contents in the brain are from brain mast cells, mediators from brain mast cells may significantly influence sleep and other behaviors. In this study, we examined potential involvement of brain mast cells in sleep/wake regulations, focusing especially on the histaminergic system, using mast cell deficient (W/Wv) mice. No significant difference was found in the basal amount of sleep/wake between W/Wv mice and their wild-type littermates (WT), although W/Wv mice showed increased EEG delta power and attenuated rebound response after sleep deprivation. Intracerebroventricular injection of compound 48/80, a histamine releaser from mast cells, significantly increased histamine levels in the ventricular region and enhanced wakefulness in WT mice, while it had no effect in W/Wv mice. Injection of H1 antagonists (triprolidine and mepyramine) significantly increased the amounts of slow-wave sleep in WT mice, but not in W/Wv mice. Most strikingly, the food-seeking behavior observed in WT mice during food deprivation was completely abolished in W/Wv mice. W/Wv mice also exhibited higher anxiety and depression levels compared to WT mice. Our findings suggest that histamine released from brain mast cells is wake-promoting, and emphasizes the physiological and pharmacological importance of brain mast cells in the regulation of sleep and fundamental neurobehavior. PMID:24205232

  2. Mast cells modulate acute ozone-induced inflammation of the murine lung

    SciTech Connect

    Kleeberger, S.R.; Seiden, J.E.; Levitt, R.C.; Zhang, L.Y. )

    1993-11-01

    We hypothesized that mast cells modulate lung inflammation that develops after acute ozone (O3) exposure. Two tests were done: (1) genetically mast-cell-deficient (WBB6F1-W/Wv, WCB6F1-SI/SId) and bone-marrow-transplanted W/Wv mice were exposed to O3 or filtered air, and the inflammatory responses were compared with those of mast-cell-sufficient congenic mice (WBB6F1-(+)/+, WCB6F1-(+)/+); (2) genetically O3-susceptible C57BL/6J mice were treated pharmacologically with putative mast-cell modulators or vehicle, and the O3-induced inflammatory responses were compared. Mice were exposed to 1.75 ppm O3 or air for 3 h, and lung inflammation was assessed by bronchoalveolar lavage (BAL) 6 and 24 h after exposure. Relative to O3-exposed W/Wv and SI/SId mice, the mean numbers of lavageable polymorphonuclear leukocytes (PMNs) and total BAL protein concentration (a marker of permeability) were significantly greater in the respective O3-exposed normal congenic +/+ mice (p < 0.05). Mast cells were reconstituted in W/Wv mice by transplantation of bone marrow cells from congenic +/+ mice, and O3-induced lung inflammation was assessed in the mast-cell-replete W/Wv mice. After O3 exposure, the changes in lavageable PMNs and total protein of mast-cell-replete W/Wv mice were not different from age-matched normal +/+ control mice, and they were significantly greater than those of sham-transplanted W/Wv mice (p < 0.05). Genetically susceptible C57BL/6J mice were pretreated with a mast-cell stabilizer (nedocromil sodium), secretagogue (compound 48/80), or vehicle, and the mice were exposed to O3.

  3. Intranasal immunization with a formalin-inactivated human influenza A virus whole-virion vaccine alone and intranasal immunization with a split-virion vaccine with mucosal adjuvants show similar levels of cross-protection.

    PubMed

    Okamoto, Shigefumi; Matsuoka, Sumiko; Takenaka, Nobuyuki; Haredy, Ahmad M; Tanimoto, Takeshi; Gomi, Yasuyuki; Ishikawa, Toyokazu; Akagi, Takami; Akashi, Mitsuru; Okuno, Yoshinobu; Mori, Yasuko; Yamanishi, Koichi

    2012-07-01

    The antigenicity of seasonal human influenza virus changes continuously; thus, a cross-protective influenza vaccine design needs to be established. Intranasal immunization with an influenza split-virion (SV) vaccine and a mucosal adjuvant induces cross-protection; however, no mucosal adjuvant has been assessed clinically. Formalin-inactivated intact human and avian viruses alone (without adjuvant) induce cross-protection against the highly pathogenic H5N1 avian influenza virus. However, it is unknown whether seasonal human influenza formalin-inactivated whole-virion (WV) vaccine alone induces cross-protection against strains within a subtype or in a different subtype of human influenza virus. Furthermore, there are few reports comparing the cross-protective efficacy of the WV vaccine and SV vaccine-mucosal adjuvant mixtures. Here, we found that the intranasal human influenza WV vaccine alone induced both the innate immune response and acquired immune response, resulting in cross-protection against drift variants within a subtype of human influenza virus. The cross-protective efficacy conferred by the WV vaccine in intranasally immunized mice was almost the same as that conferred by a mixture of SV vaccine and adjuvants. The level of cross-protective efficacy was correlated with the cross-reactive neutralizing antibody titer in the nasal wash and bronchoalveolar fluids. However, neither the SV vaccine with adjuvant nor the WV vaccine induced cross-reactive virus-specific cytotoxic T-lymphocyte activity. These results suggest that the intranasal human WV vaccine injection alone is effective against variants within a virus subtype, mainly through a humoral immune response, and that the cross-protection elicited by the WV vaccine and the SV vaccine plus mucosal adjuvants is similar.

  4. Concentration selective hydration and phase states of hydroxyethyl cellulose (HEC) in aqueous solutions.

    PubMed

    Arfin, Najmul; Bohidar, H B

    2012-04-01

    Solution behaviour of hydroxyethyl cellulose (HEC) is reported in the polymer concentration range spanning over two decades (c=0.002-5% (w/v)). The results conclude the following: (i) dilute solution regime prevailed for c<0.2% (w/v), flexible HEC fibres of typical length ≈ 1 μm and persistence length ≈ 10 nm were found here, (ii) for 0.2w/v), a semidilute phase comprising soluble aggregates of hydrated HEC fibrils were observed with the material exhibiting viscoelastic behaviour and (iii) when 1w/v) the solution behaved with melt-like attributes with substantial embedded heterogeneity; viscous to elastic transition was observed in this region. Raman spectral, and DSC data indicated distinctive hydration of HEC fibres in the aforesaid concentration regimes. Cole-Cole plots revealed phase homogeneity and miscibility was limited to concentrations less than ~2% (w/v). For higher polymer concentrations, strong fibre-fibre interactions prevailed and samples became heterogeneous.

  5. Relative Humidity Distributions in the Tropical Tropopause Layer Measured During NASA ATTREX

    NASA Astrophysics Data System (ADS)

    Rollins, A. W.; Thornberry, T. D.; Gao, R. S.; Woods, S.; Bui, T. V.; Fahey, D. W.

    2014-12-01

    Removal of water vapor (WV) from the gas phase to form cirrus clouds in the tropical tropopause layer (TTL) is the primary control over the concentration and temporal variability of stratospheric WV. A complete understanding of the associated chemical and microphysical processes and quantitative predictive power of the frequency with which these clouds form and the efficiency with which they dehydrate air masses has been elusive, largely due to insufficiencies in measurements both of WV and cirrus microphysical properties. Observations provided by the NASA Airborne Tropical Tropopause Experiment (ATTREX) are helping to significantly close the gap between measurements and theory with respect to TTL cirrus and stratospheric WV. We will show that while the observed humidity inside and outside of TTL cirrus clouds is frequently supersaturated with respect to hexagonal ice, these measurements are in good agreement with conventional theories of ice nucleation and deposition. The ATTREX observations provide valuable statistics of relative humidity (RHi) in the TTL. We use these observations to evaluate the frequency distribution of RHi inside and outside of cirrus clouds, and begin to constrain the error that may be incurred in models that calculate stratospheric WV by assuming RHi does not exceed 100% in the TTL.

  6. Potential of carboxymethyl cellulose and γ-irradiation to maintain quality and control disease of peach fruit.

    PubMed

    Hussain, Peerzada R; Suradkar, Prashant P; Wani, Ali M; Dar, Mohd A

    2016-01-01

    Carboxymethyl cellulose (CMC) coatings alone and in combination with gamma irradiation were tested for maintaining the storage quality and control of post-harvest gray and black mold disease of peach. Matured green peaches were CMC coated at levels 0.5-1.0% (w/v) and gamma irradiated at 1.2 kGy. The treated fruit including control was stored under ambient (temperature 25 ± 2°C, RH 70%) and refrigerated (temperature 3 ± 1°C, RH 80%) conditions. In fruits treated with individual treatments of 1.0% (w/v) CMC; 1.2 kGy irradiation and combination of 1.0% (w/v) CMC and 1.2 kGy irradiation, no decay was recorded up to 6, 8 and 14 days of ambient storage. Irradiation alone at 1.2 kGy prevented the onset of disease incidence up to 4 days compared to 2 days by 1.0% (w/v) CMC coating following 30 days of refrigeration. Combination of CMC at 1.0% (w/v) and 1.2 kGy irradiation prevented disease incidence of peach up to 7 days during post-refrigerated storage at 25 ± 2°C, RH 70% following 30 days of refrigeration. Above combinatory treatment can be of great potential in facilitating the marketing of the fruit, thereby benefiting the growers. PMID:26427648

  7. The Exploding Spark: Workplace Violence in an Infectious Disease Hospital—A Longitudinal Study

    PubMed Central

    2013-01-01

    Objectives. Workplace violence (WV) is an important occupational hazard for healthcare workers (HCWs). Methods. A longitudinal study was carried out on HCWs from an infectious disease hospital. Work-related stress, anxiety, and depression were measured at baseline in 2003, and they were reassessed in 2005, along with the assaults that occurred in the previous year. Results. One-year prevalences of 6.2% and 13.9% were reported for physical and verbal aggressions, respectively. Perpetrators were mainly patients. The professional groups most frequently attacked were physicians, followed by nurses. Workers with job strain at baseline had a significant risk of being subject to aggression (OR 7.7; CI 95%, 3.3–17.9) in the following year. The relationship between job strain and subsequent WV remained significant even after correction for anxiety, depression, and other confounders. Conversely, experiencing WV was associated with a high risk of job strain and effort-reward imbalance in the following year. The final levels of anxiety and depression were predicted using regression models that included physical aggression among predictive variables. Conclusions. WV is the spark that sets off a problematic work situation. Effective prevention of WV can only be achieved within the framework of an overall improvement in the quality of work. PMID:23936789

  8. Potential of carboxymethyl cellulose and γ-irradiation to maintain quality and control disease of peach fruit.

    PubMed

    Hussain, Peerzada R; Suradkar, Prashant P; Wani, Ali M; Dar, Mohd A

    2016-01-01

    Carboxymethyl cellulose (CMC) coatings alone and in combination with gamma irradiation were tested for maintaining the storage quality and control of post-harvest gray and black mold disease of peach. Matured green peaches were CMC coated at levels 0.5-1.0% (w/v) and gamma irradiated at 1.2 kGy. The treated fruit including control was stored under ambient (temperature 25 ± 2°C, RH 70%) and refrigerated (temperature 3 ± 1°C, RH 80%) conditions. In fruits treated with individual treatments of 1.0% (w/v) CMC; 1.2 kGy irradiation and combination of 1.0% (w/v) CMC and 1.2 kGy irradiation, no decay was recorded up to 6, 8 and 14 days of ambient storage. Irradiation alone at 1.2 kGy prevented the onset of disease incidence up to 4 days compared to 2 days by 1.0% (w/v) CMC coating following 30 days of refrigeration. Combination of CMC at 1.0% (w/v) and 1.2 kGy irradiation prevented disease incidence of peach up to 7 days during post-refrigerated storage at 25 ± 2°C, RH 70% following 30 days of refrigeration. Above combinatory treatment can be of great potential in facilitating the marketing of the fruit, thereby benefiting the growers.

  9. From high tech to high touch: integrating community voices in mobile mammography outreach.

    PubMed

    Kennedy, Stephenie; Stephens, Sheila; Tephabock, Kevin; Brown, Pamela; Davis, Patty; Keresztury, James; Narsavage, Georgia

    2009-10-01

    Providing mobile screening mammography services across the state of West Virginia (WV) presents unique challenges. The ability of new machines to screen for breast cancer is modern medicine at its best. The use of the mobile unit, "Bonnie's Bus", holds promise for getting this high tech equipment to women in rural areas of West Virginia where it is most needed. Cancer detected in early stages is more treatable and women have a better chance of becoming survivors. The key to the program's success resides with the women who come for the screening, the extension network of community members who help set up and assist women to access the screening system, and community health care providers who care for the women if cancer is found. Linking "community voices" with the programs funded under the WV Komen grant screening programs provides a winning solution for West Virginia and the women served by Bonnie's Bus. Information obtained from five focus groups of 58 community leaders and women residing in rural WV was used to develop the mobile program. Building upon established relationships with the West Virginia Breast and Cervical Cancer Screening Program (WV BCCSP) coordinators and providers, outreach and information gleaned from WV communities, is being used to develop community partnerships based on mutual trust and respect to advance the common goal of decreasing breast cancer related illness and death in West Virginia women. PMID:19999271

  10. Formulation and optimization of ethosomes for transdermal delivery of ropinirole hydrochloride.

    PubMed

    Mishra, Ashish D; Patel, C N; Shah, Dinesh R

    2013-10-01

    The present study focuses on the formulation of ethosomal gel of ropinirole hydrochloride (ropinirole HCl), an anti-Parkinsonian drug, for delivery as a carrier for transdermal application. The ethosomes were prepared using different concentrations of phospholipids (2-5 % w/v), ethanol (20-50 % w/v), ropinirole HCl (5 % w/v) and water. They were optimized using 3(2) full factorial designs to study the effect of independent variables, concentrations of ethanol and lecithin on dependent variables, entrapment efficiency and in-vitro drug release at 24 hrs. The drug release profile exhibited Higuchi's and zero order kinetics. From the regression analysis, it was observed that independent variables had significant effect on response variables. Formulations were optimized using contour plot and response surface plot. The optimized formulation was found to be RS10 containing 30 % w/v ethanol and 4% w/v lecithin. The optimized formulation was evaluated for assay, particle characteristics, zeta potential, skin retention and stability. Ethosomal gel was prepared by incorporation of optimized ethosomal suspension into gel base. The ethosomal gel was characterized for physical appearance, pH, content uniformity, rheological behaviour, skin-retention, in-vitro and in-vivo drug release and stability. From the results it can fairly be concluded that ethosomes are capable of delivering ropinirole hydrochloride into systemic circulation by transdermal route. The amounts thus delivered are also equitable to those delivered orally and are delivered at a rate slow enough to achieve longer blood levels. PMID:23410071

  11. Formulation and optimization of ethosomes for transdermal delivery of ropinirole hydrochloride.

    PubMed

    Mishra, Ashish D; Patel, C N; Shah, Dinesh R

    2013-10-01

    The present study focuses on the formulation of ethosomal gel of ropinirole hydrochloride (ropinirole HCl), an anti-Parkinsonian drug, for delivery as a carrier for transdermal application. The ethosomes were prepared using different concentrations of phospholipids (2-5 % w/v), ethanol (20-50 % w/v), ropinirole HCl (5 % w/v) and water. They were optimized using 3(2) full factorial designs to study the effect of independent variables, concentrations of ethanol and lecithin on dependent variables, entrapment efficiency and in-vitro drug release at 24 hrs. The drug release profile exhibited Higuchi's and zero order kinetics. From the regression analysis, it was observed that independent variables had significant effect on response variables. Formulations were optimized using contour plot and response surface plot. The optimized formulation was found to be RS10 containing 30 % w/v ethanol and 4% w/v lecithin. The optimized formulation was evaluated for assay, particle characteristics, zeta potential, skin retention and stability. Ethosomal gel was prepared by incorporation of optimized ethosomal suspension into gel base. The ethosomal gel was characterized for physical appearance, pH, content uniformity, rheological behaviour, skin-retention, in-vitro and in-vivo drug release and stability. From the results it can fairly be concluded that ethosomes are capable of delivering ropinirole hydrochloride into systemic circulation by transdermal route. The amounts thus delivered are also equitable to those delivered orally and are delivered at a rate slow enough to achieve longer blood levels.

  12. Genome-scale metabolic modeling of Mucor circinelloides and comparative analysis with other oleaginous species.

    PubMed

    Vongsangnak, Wanwipa; Klanchui, Amornpan; Tawornsamretkit, Iyarest; Tatiyaborwornchai, Witthawin; Laoteng, Kobkul; Meechai, Asawin

    2016-06-01

    We present a novel genome-scale metabolic model iWV1213 of Mucor circinelloides, which is an oleaginous fungus for industrial applications. The model contains 1213 genes, 1413 metabolites and 1326 metabolic reactions across different compartments. We demonstrate that iWV1213 is able to accurately predict the growth rates of M. circinelloides on various nutrient sources and culture conditions using Flux Balance Analysis and Phenotypic Phase Plane analysis. Comparative analysis of three oleaginous genome-scale models, including M. circinelloides (iWV1213), Mortierella alpina (iCY1106) and Yarrowia lipolytica (iYL619_PCP) revealed that iWV1213 possesses a higher number of genes involved in carbohydrate, amino acid, and lipid metabolisms that might contribute to its versatility in nutrient utilization. Moreover, the identification of unique and common active reactions among the Zygomycetes oleaginous models using Flux Variability Analysis unveiled a set of gene/enzyme candidates as metabolic engineering targets for cellular improvement. Thus, iWV1213 offers a powerful metabolic engineering tool for multi-level omics analysis, enabling strain optimization as a cell factory platform of lipid-based production.

  13. Statistical media and process optimization for biotransformation of rice bran to vanillin using Pediococcus acidilactici.

    PubMed

    Kaur, Baljinder; Chakraborty, Debkumar

    2013-11-01

    An isolate of P. acidilactici capable of producing vanillin from rice bran was isolated from a milk product. Response Surface Methodology was employed for statistical media and process optimization for production of biovanillin. Statistical medium optimization was done in two steps involving Placket Burman Design and Central Composite Response Designs. The RSM optimized vanillin production medium consisted of 15% (w/v) rice bran, 0.5% (w/v) peptone, 0.1% (w/v) ammonium nitrate, 0.005% (w/v) ferulic acid, 0.005% (w/v) magnesium sulphate, and 0.1% (v/v) tween-80, pH 5.6, at a temperature of 37 degrees C under shaking conditions at 180 rpm. 1.269 g/L vanillin was obtained within 24 h of incubation in optimized culture medium. This is the first report indicating such a high vanillin yield obtained during biotransformation of ferulic acid to vanillin using a Pediococcal isolate.

  14. Photo-crosslinkable hydrogel-based 3D microfluidic culture device.

    PubMed

    Lee, Youlee; Lee, Jong Min; Bae, Pan-Kee; Chung, Il Yup; Chung, Bong Hyun; Chung, Bong Geun

    2015-04-01

    We developed the photo-crosslinkable hydrogel-based 3D microfluidic device to culture neural stem cells (NSCs) and tumors. The photo-crosslinkable gelatin methacrylate (GelMA) polymer was used as a physical barrier in the microfluidic device and collagen type I gel was employed to culture NSCs in a 3D manner. We demonstrated that the pore size was inversely proportional to concentrations of GelMA hydrogels, showing the pore sizes of 5 and 25 w/v% GelMA hydrogels were 34 and 4 μm, respectively. It also revealed that the morphology of pores in 5 w/v% GelMA hydrogels was elliptical shape, whereas we observed circular-shaped pores in 25 w/v% GelMA hydrogels. To culture NSCs and tumors in the 3D microfluidic device, we investigated the molecular diffusion properties across GelMA hydrogels, indicating that 25 w/v% GelMA hydrogels inhibited the molecular diffusion for 6 days in the 3D microfluidic device. In contrast, the chemicals were diffused in 5 w/v% GelMA hydrogels. Finally, we cultured NSCs and tumors in the hydrogel-based 3D microfluidic device, showing that 53-75% NSCs differentiated into neurons, while tumors were cultured in the collagen gels. Therefore, this photo-crosslinkable hydrogel-based 3D microfluidic culture device could be a potentially powerful tool for regenerative tissue engineering applications.

  15. The longitudinal effects of resisted sprint training using weighted sleds vs. weighted vests.

    PubMed

    Clark, Kenneth P; Stearne, David J; Walts, Cory T; Miller, Anthony D

    2010-12-01

    The purpose of this study was to determine the longitudinal effects of weighted sled (WS) and weighted vest (WV) sprint training on maximum velocity sprint performance and kinematics. Twenty male collegiate lacrosse players were randomly assigned to a WS group (n = 7) towing 10% body mass, a WV group (n = 6) loaded with 18.5% body mass, or an unresisted (UR) active control group (n = 7). All subjects completed 13 training sessions over 7 weeks. Pre- and post-test measures of sprint time and average velocity across the distance interval of 18.3 to 54.9 m were used to assess sprint performance, whereas high-speed video (300 Hz) and motion-analysis software were used to analyze stride length, stride rate, ground contact time, and flight time. A 3 × 2 repeated measures analysis of variance was performed for each dependent variable and revealed no significant between-group differences for any of the sprint performance or kinematic stride cycle measures. Effect size statistics suggested small improvements in 18.3- to 54.9-m sprint time and average velocity for the UR group but only trivial improvements for the WS and WV groups. With regard to sprint performance, the results indicate that WS and WV training had no beneficial effect compared with UR training. In fact, for the loads used by WS and WV in this study, UR training may actually be superior for improving sprint performance in the 18.3- to 54.9-m interval.

  16. Quantifying Libya-4 Surface Reflectance Heterogeneity With WorldView-1, 2 and EO-1 Hyperion

    NASA Technical Reports Server (NTRS)

    Neigh, Christopher S. R.; McCorkel, Joel; Middleton, Elizabeth M.

    2015-01-01

    The land surface imaging (LSI) virtual constellation approach promotes the concept of increasing Earth observations from multiple but disparate satellites. We evaluated this through spectral and spatial domains, by comparing surface reflectance from 30-m Hyperion and 2-m resolution WorldView-2 (WV-2) data in the Libya-4 pseudoinvariant calibration site. We convolved and resampled Hyperion to WV-2 bands using both cubic convolution and nearest neighbor (NN) interpolation. Additionally, WV-2 and WV-1 same-date imagery were processed as a cross-track stereo pair to generate a digital terrain model to evaluate the effects from large (>70 m) linear dunes. Agreement was moderate to low on dune peaks between WV-2 and Hyperion (R2 <; 0.4) but higher in areas of lower elevation and slope (R2 > 0.6). Our results provide a satellite sensor intercomparison protocol for an LSI virtual constellation at high spatial resolution, which should start with geolocation of pixels, followed by NN interpolation to avoid tall dunes that enhance surface reflectance differences across this internationally utilized site.

  17. Preconcentration procedure using cloud point extraction in the presence of electrolyte for cadmium determination by flame atomic absorption spectrometry

    NASA Astrophysics Data System (ADS)

    Coelho, Luciana Melo; Arruda, Marco Aurélio Zezzi

    2005-06-01

    This paper describes a micelle-mediated phase separation in the presence of electrolyte as a preconcentration method for cadmium determination by flame atomic absorption spectrometry (FAAS). Cadmium was complexed with ammonium O,O-diethyldithiophosphate (DDTP) in an acidic medium (0.32 mol l- 1 HCl) using Triton X-114 as surfactant and quantitatively extracted into a small volume (about 20 μl) of the surfactant-rich phase after centrifugation. The chemical variables that affect the cloud point extraction, such as complexing time (0 20 min), Triton X114 concentration (0.043 0.87% w/v) and complexing agent concentration (0.01 0.1 mol l- 1), were investigated. The cloud point is formed in the presence of NaCl at room temperature (25 °C), and the electrolyte concentration (0.5 5% w/v) was also investigated. Under optimized conditions, only 8 ml of sample was used in the presence of 0.043% w/v Triton X-114 and 1% (w/v) NaCl. This method permitted limits of detection and quantification of 0.9 μg l- 1 and 2.9 μg l- 1 Cd, respectively, and a linear calibration range from 3 to 400 μg l- 1 Cd. The proposed method was applied to Cd determination in physiological solutions (containing 0.9% (w/v) of NaCl), mineral water, lake water and cigarette samples (tobacco).

  18. Leaf age affects the responses of foliar injury and gas exchange to tropospheric ozone in Prunus serotina seedlings.

    PubMed

    Zhang, Jianwei; Schaub, Marcus; Ferdinand, Jonathan A; Skelly, John M; Steiner, Kim C; Savage, James E

    2010-08-01

    We investigated the effect of leaf age on the response of net photosynthesis (A), stomatal conductance (g(wv)), foliar injury, and leaf nitrogen concentration (N(L)) to tropospheric ozone (O(3)) on Prunus serotina seedlings grown in open-plots (AA) and open-top chambers, supplied with either carbon-filtered or non-filtered air. We found significant variation in A, g(wv), foliar injury, and N(L) (P < 0.05) among O(3) treatments. Seedlings in AA showed the highest A and g(wv) due to relatively low vapor pressure deficit (VPD). Older leaves showed significantly lower A, g(wv), N(L), and higher foliar injury (P < 0.001) than younger leaves. Leaf age affected the response of A, g(wv), and foliar injury to O(3). Both VPD and N(L) had a strong influence on leaf gas exchange. Foliar O(3)-induced injury appeared when cumulative O(3) uptake reached 8-12 mmol m(-2), depending on soil water availability. The mechanistic assessment of O(3)-induced injury is a valuable approach for a biologically relevant O(3) risk assessment for forest trees. PMID:20537450

  19. A study of the impact of synoptic weather conditions and water vapor on aerosol-cloud relationships over major urban clusters of China

    NASA Astrophysics Data System (ADS)

    Kourtidis, K.; Stathopoulos, S.; Georgoulias, A. K.; Alexandri, G.; Rapsomanikis, S.

    2015-10-01

    The relationships between aerosol optical depth (AOD), cloud cover (CC), and cloud top pressure (CTP) over three major urban clusters in China are studied under different sea level pressure (SLP) and water vapor (WV) regimes using a decade (2003-2013) of MODIS satellite-retrieved data. Over all urban clusters, for all SLP regimes, CC is found to increase with AOD, thus pointing out that the CC dependence on AOD cannot be explained by synoptic covariation, as approximated by SLP, alone. WV is found to have a stronger impact on CC than AOD. This impact is more pronounced at high aerosol load than at low aerosol load. Hence, studies of AOD-CC relationships, based on satellite data, will greatly overestimate the AOD impact on CC in regions where AOD and WV have similar seasonal variations, while they will probably underestimate the AOD impact in regions where AOD and WV have opposite seasonal variations. Further, this impact shows that the hydrological cycle interferes with the aerosol climatic impact and we need to improve our understanding of this interference. Our results also suggest that studies attributing CTP long-term changes to changes in aerosol load might have a WV bias.

  20. Effect of Alginate Concentration on Alginate-TiO2 Hydrogel for Lead Ion Removal

    NASA Astrophysics Data System (ADS)

    Teoh, W. T.; Saito, N.; Sato, K.

    2011-03-01

    Alginate-TiO2 hydrogel was investigated for lead ion (Pb(II)) removal. By immobilizing TiO2 powder onto an alginate biopolymer, it is possible to utilize the ion exchange properties of the alginate and the photoreducibility of TiO2 to recover Pb(II). However, these photocatalytic activities degrade the alginate biopolymer in addition to removing Pb(II). This study examines photolytic degradation of alginate-TiO2 hydrogels prepared with alginate concentrations of 1, 1.5, 2, and 2.5%w/v; the same amount (0.4%w/v) of TiO2 was added to each alginate solution. The alginate-TiO2 hydrogels were formed by dripping the alginate-TiO2 suspension into a 0.2 M calcium chloride solution. The samples were washed and dried and then photoirradiated. The samples with alginate concentrations of 1 and 1.5%w/v were depolymerized, whereas the surface morphology of the sample that prepared from the 2%w/v alginate solution remained unchanged. The samples prepared from 1.5, 2, and 2.5%w/v alginate solutions had Pb(II) uptakes of 24.0, 39.8, and 39.7 mg/g, respectively.

  1. Enhanced production of bacterial cellulose by using Gluconacetobacter hansenii NCIM 2529 strain under shaking conditions.

    PubMed

    Mohite, Bhavna V; Salunke, Bipinchandra K; Patil, Satish V

    2013-03-01

    Bacterial cellulose (BC), a biopolymer, due to its unique properties is valuable for production of vital products in food, textile, medicine, and agriculture. In the present study, the optimal fermentation conditions for enhanced BC production by Gluconacetobacter hansenii NCIM 2529 were investigated under shaking conditions. The investigation on media components and culture parameters revealed that 2 % (w/v) sucrose as carbon source, 0.5 % (w/v) potassium nitrate as nitrogen source, 0.4 % (w/v) disodium phosphate as phosphate source, 0.04 % (w/v) magnesium sulfate, and 0.8 % (w/v) calcium chloride as trace elements, pH5.0, temperature 25 °C, and agitation speed 170 rpm with 6 days of fermentation period are optimal for maximum BC production. Production of BC using optimized media components and culture parameters was 1.66 times higher (5.0 g/l) than initial non optimized media (3.0 g/l). Fourier transform infrared spectroscopy spectrum and comparison with the available literature suggests that the produced component by G. hansenii in the present study is pure bacterial cellulose. The specific action of cellulase out of the investigated hydrolytic enzymes (cellulase, amylase, and protease) further confirmed purity of the produced BC. These findings give insight into conditions necessary for enhanced production of bacterial cellulose, which can be used for a variety of applications.

  2. Influence of the alkaline delignification on the simultaneous saccharification and fermentation (SSF) of sugar cane bagasse.

    PubMed

    Soares, Mariana Lucena; Gouveia, Ester Ribeiro

    2013-11-01

    Ethanol production from steam explosion alkaline delignified bagasse was investigated by saccharification and simultaneous fermentation. Non delignified bagasse (ND) contained 25% lignin, and after alkaline delignification, materials with 6% (D1 - NaOH 1% w/v) and 12% (D05 - NaOH 0.5% w/v) lignin, respectively, were obtained. Ethanol production increased 450% and 733% in relation to ND, when D05 and D1 material, respectively, were used. Higher productivity and EtOH/bagasse were observed for D1. However, higher enzymatic convertibility of cellulose was obtained with 0.5% w/v NaOH. Alkaline delignification increased the ethanol production despite decreased cellulose.

  3. Efficient butanol recovery from acetone-butanol-ethanol fermentation cultures grown on sweet sorghum juice by pervaporation using silicalite-1 membrane.

    PubMed

    Kanemoto, Miho; Negishi, Hideyuki; Sakaki, Keiji; Ikegami, Toru; Chohnan, Shigeru; Nitta, Youji; Kurusu, Yasurou; Ohta, Hiroyuki

    2016-06-01

    We investigated butanol recovery by pervaporation separation, using a silicalite-1 membrane, from batch cultures of butanol-producing Clostridium beijerinckii SBP2 grown on sweet sorghum juice as a fermentation medium. The pervaporation system yielded 73% (w/v) butanol from intact feed cultures containing 1% (w/v) butanol, and had a butanol permeation flux of 11 g m(-2) h(-1). Upon neutralization and activated charcoal treatment of the feed cultures, butanol yield and total flux increased to 82% (w/v) and 40 g m(-2) h(-1), respectively. This system is applicable to refining processes for practical biobutanol production from a promising energy crop, sweet sorghum.

  4. Hydrogen production from glucose by anaerobes.

    PubMed

    Ogino, Hiroyasu; Miura, Takashi; Ishimi, Kosaku; Seki, Minoru; Yoshida, Hiroyuki

    2005-01-01

    Various anaerobes were cultivated in media containing glucose. When 100 mL of thioglycollate medium containing 2.0% (w/v) glucose was used, Clostridium butyricum ATCC 859, NBRC 3315, and NBRC 13949 evolved 227-243 mL of biogas containing about 180 mL of hydrogen in 1 day. Although some strains had some resistance against oxygen, C. butyricum ATCC 859 and 860 did not have it. C. butyricum NBRC 3315 and Enterobacter aerogenes NBRC 13534 produced hydrogen in the presence of glucose or pyruvic acid, and E. aerogenes NBRC 13534 produced hydrogen by not only glucose and pyruvic acid but also dextrin, sucrose, maltose, galactose, fructose, mannose, and mannitol. When a medium containing 0.5% (w/v) yeast extract and 2.0% (w/v) glucose was used, E. aerogenes NBRC 13534 evolved more biogas and hydrogen than C. butyricum NBRC 3315 in the absence of reducing agent.

  5. Development and evaluation of tamarind seed xyloglucan-based mucoadhesive buccal films of rizatriptan benzoate.

    PubMed

    Avachat, Amelia M; Gujar, Kishore N; Wagh, Kishor V

    2013-01-16

    Mucoadhesive buccal films were developed using tamarind seed xyloglucan (TSX) as novel mucoadhesive polysaccharide polymer for systemic delivery of rizatriptan benzoate through buccal route. Formulations were prepared based on 3(2) factorial design with concentrations of TSX and carbopol 934P (CP) as independent variables. Three dependent variables considered were tensile strength, bioadhesion force and drug release. DSC analysis revealed no interaction between drug and polymers. Ex vivo diffusion studies were carried out using Franz diffusion cell, while bioadhesive properties were evaluated using texture analyzer with porcine buccal mucosa as model tissue. Results revealed that bilayer film containing 4% (w/v) TSX and 0.5% (w/v) CP in the drug layer and 1% (w/v) ethyl cellulose in backing layer demonstrated diffusion of 93.45% through the porcine buccal mucosa. Thus, this study suggests that tamarind seed polysaccharide can act as a potential mucoadhesive polymer for buccal delivery of a highly soluble drug like rizatriptan benzoate.

  6. Plasmacytoid dendritic cells delineate immunogenicity of influenza vaccine subtypes.

    PubMed

    Koyama, Shohei; Aoshi, Taiki; Tanimoto, Takeshi; Kumagai, Yutaro; Kobiyama, Kouji; Tougan, Takahiro; Sakurai, Kazuo; Coban, Cevayir; Horii, Toshihiro; Akira, Shizuo; Ishii, Ken J

    2010-03-31

    A variety of different vaccine types are available for H1N1 influenza A virus infections; however, their immunological mechanisms of action remain unclear. Here, we show that plasmacytoid dendritic cells (pDCs) and type I interferon (IFN)-mediated signaling delineate the immunogenicity of live attenuated virus, inactivated whole-virus (WV), and split-virus vaccines. Although Toll-like receptor 7 acted as the adjuvant receptor for the immunogenicity of both live virus and WV vaccines, the requirement for type I IFN production by pDCs for the immunogenicity of the vaccines was restricted to WV. A split vaccine commonly used in humans failed to immunize naïve mice, but a pDC-activating adjuvant could restore immunogenicity. In blood from human adults, however, split vaccine alone could recall memory T cell responses, underscoring the importance of this adjuvant pathway for primary, but not secondary, vaccination. PMID:20424013

  7. A demonstration of the susceptibility of clinical isolates obtained from cystic fibrosis patients to manuka honey.

    PubMed

    Jenkins, Rowena; Wootton, Mandy; Howe, Robin; Cooper, Rose

    2015-05-01

    Pseudomonas and Burkholderia pose a significant health threat to people with chronic respiratory conditions; the resistance inherent in these bacteria indicates that new antimicrobial strategies are required. Susceptibility of 56 strains of P. aeruginosa and 55 strains of Burkholderia to manuka honey, tobramycin and colistin using microbroth dilution and E strip was determined. MICs of antibiotics with honey were determined to search for synergistic combinations against two representative strains of each genus. All strains exhibited susceptibility to honey ≤10 % (w/v); mean susceptibility of Burkholderia (4.6 % w/v) was lower than P. aeruginosa (7.3 % w/v). Synergistic or additive combinations were found with all four strains tested. Combinations of manuka honey with antibiotics can be used to lower the MIC need to successfully inhibit both P. aeruginosa and B. cepacia. The use of honey as a combination agent may be possible for the management of P. aeruginosa and B. cepacia. PMID:25680398

  8. Antibacterial and antifungal activity of Iranian propolis against Staphylococcus aureus and Candida albicans.

    PubMed

    Ghasem, Yousef-Beigi; Ownagh, Abdolghaffar; Hasanloei, M

    2007-04-15

    Propolis samples from West North region of Iran were studied for their antibacterial (against Staphylococcus aureus) and antifungal (against Candida albicans) activities. In this article, yield of extracts and their pH values were measured. Antibacterial and antifungal activities of Ethanol-Extracted Propolis (EEP) were investigated by Petri dish bioassay method. Dilutions of EPP in agar with serial concentrations ranging from 0/04 to 10% (W/V) were prepared and antimicrobial activities were determined as Minimal Inhibitory Concentrations (MIC). All samples were active against the fungal and bacterial test strains. MIC values for different propolis samples against Staphylococcus aureus were, respectively 4, 3 and 1.5% (W/V) and against Candida albicans were, respectively 2, 4 and 3% (W/V).

  9. Bioleaching of rare earth and radioactive elements from red mud using Penicillium tricolor RM-10.

    PubMed

    Qu, Yang; Lian, Bin

    2013-05-01

    The aim of this work is to investigate biological leaching of rare earth elements (REEs) and radioactive elements from red mud, and to evaluate the radioactivity of the bioleached red mud used for construction materials. A filamentous, acid-producing fungi named RM-10, identified as Penicillium tricolor, is isolated from red mud. In our bioleaching experiments by using RM-10, a total concentration of 2% (w/v) red mud under one-step bioleaching process was generally found to give the maximum leaching ratios of the REEs and radioactive elements. However, the highest extraction yields are achieved under two-step bioleaching process at 10% (w/v) pulp density. At pulp densities of 2% and 5% (w/v), red mud processed under both one- and two-step bioleaching can meet the radioactivity regulations in China.

  10. A demonstration of the susceptibility of clinical isolates obtained from cystic fibrosis patients to manuka honey.

    PubMed

    Jenkins, Rowena; Wootton, Mandy; Howe, Robin; Cooper, Rose

    2015-05-01

    Pseudomonas and Burkholderia pose a significant health threat to people with chronic respiratory conditions; the resistance inherent in these bacteria indicates that new antimicrobial strategies are required. Susceptibility of 56 strains of P. aeruginosa and 55 strains of Burkholderia to manuka honey, tobramycin and colistin using microbroth dilution and E strip was determined. MICs of antibiotics with honey were determined to search for synergistic combinations against two representative strains of each genus. All strains exhibited susceptibility to honey ≤10 % (w/v); mean susceptibility of Burkholderia (4.6 % w/v) was lower than P. aeruginosa (7.3 % w/v). Synergistic or additive combinations were found with all four strains tested. Combinations of manuka honey with antibiotics can be used to lower the MIC need to successfully inhibit both P. aeruginosa and B. cepacia. The use of honey as a combination agent may be possible for the management of P. aeruginosa and B. cepacia.

  11. Wake modeling in complex terrain using a hybrid Eulerian-Lagrangian Split Solver

    NASA Astrophysics Data System (ADS)

    Fuchs, Franz G.; Rasheed, Adil; Tabib, Mandar; Fonn, Eivind

    2016-09-01

    Wake vortices (WVs) generated by aircraft are a source of risk to the following aircraft. The probability of WV related accidents increases in the vicinity of airport runways due to the shorter time of recovery after a WV encounter. Hence, solutions that can reduce the risk of WV encounters are needed to ensure increased flight safety. In this work we propose an interesting approach to model such wake vortices in real time using a hybrid Eulerian- Lagrangian approach. We derive an appropriate mathematical model, and show a comparison of the different types of solvers. We will conclude with a real life application of the methodology by simulating how wake vortices left behind by an aircraft at the Vffirnes airport in Norway get transported and decay under the influence of a background wind and turbulence field. Although the work demonstrates the application in an aviation context the same approach can be used in a wind energy context.

  12. Developing a Dissemination Model to Improve Intervention Reach among West Virginia Youth Smokers

    PubMed Central

    Horn, Kimberly; Jarrett, Traci; Anesetti-Rothermel, Andrew; O’Hara Tompkins, Nancy; Dino, Geri

    2014-01-01

    The not-on-tobacco program is an evidence-based teen smoking cessation program adopted by the American Lung Association (ALA). Although widely disseminated nationally via ALA Master Trainers, in recent years, adoption and implementation of the N-O-T program in West Virginia (WV) has slowed. WV, unfortunately, has one of the highest smoking rates in the US. Although it is a goal of public health science, dissemination of evidence-based interventions is woefully understudied. The present manuscript reviews a theoretical model of dissemination of the not-on-tobacco program in WV. Based on social marketing, diffusion of innovations, and social cognitive theories, the nine-phase model incorporates elements of infrastructure development, accountability, training, delivery, incentives, and communication. The model components as well as preliminary lessons learned from initial implementation are discussed. PMID:25136547

  13. Applications of differential scanning calorimetry in developing cryopreservation strategies for Parkia speciosa, a tropical tree producing recalcitrant seeds.

    PubMed

    Nadarajan, Jayanthi; Mansor, Marzalina; Krishnapillay, Baskaran; Staines, Harry J; Benson, Erica E; Harding, Keith

    2008-01-01

    Shoot-tips of Parkia speciosa, a recalcitrant seed producing tropical leguminous tree withstood cryopreservation using encapsulation-vitrification in combination with trehalose preculture. Differential scanning calorimetry (DSC) revealed that trehalose moderated the thermal characteristics of the shoot-tips. A 30 min PVS2 treatment had the lowest glass transition temperature (Tg) (-50.2 +/- 1.1 degree C) when applied in combination with 5% (w/v) trehalose. The Tg increased to -40.2 +/- 1.0 degree C as the sugar concentration was decreased to 2.5 percent (w/v). Tg heat capacity for shoot-tips treated with 2.5 percent and 5 percent (w/v) trehalose and exposed to PVS2 for 30 min increased from 0.17 +/ 0.05 to 0.23 +/- 0.01 J per gram, respectively. Enthalpies of the melt-endotherm varied in proportion to trehalose concentration, for the 30 min PVS2 treatment, whereas the melt enthalpy for control shoots was greater than 150 J per gram and decreased to ca. 60 J per gram with 2.5 percent (w/v) trehalose. For 5 percent and 10 percent (w/v) trehalose treatments, enthalpy declined to ca. 24 and 12 J per gram respectively and freezing points were depressed to -75 degree C and -85 degree C with 2.5 percent and 5 percent trehalose (w/v), respectively. DSC elucidated the critical points at which vitrification occurred in germplasm exposed to trehalose and PVS2. A 60 min PVS2 treatment supporting ca. 70 percent survival was found optimal for stable glass formation during cooling and on rewarming. PMID:18516340

  14. Rapid determination of yeast viability

    SciTech Connect

    Lee, S.S.; Robinson, F.M.; Wang, H.Y.

    1981-01-01

    A modified simple staining method using Methylene blue to distinguish between live and dead cells has been developed. Methylene blue (0.025%, w/v) in full strength Ringer solution with 1% glucose (w/v) added is used as the standard staining solution. Satisfactory and reproducible results can be obtained through microscopic examination using this staining method. The ratio of viable cells to nonviable cells is constant for at least two days if the proper environmental conditions are provided. This method was used to demonstrate the effects of various factors that influence yeast viability.

  15. Benzoyl peroxide versus topical erythromycin in the treatment of acne vulgaris.

    PubMed

    Burke, B; Eady, E A; Cunliffe, W J

    1983-02-01

    In a double-blind clinical study in ninety-four subjects a 1.5% (w/v) erythromycin lotion was as effective as 5% (w/v) benzoyl peroxide gel in significantly reducing the number of small inflamed lesions and the overall acne severity. However, benzoyl peroxide also significantly reduced the number of non-inflamed lesions whereas erythromycin had no effect on these lesions. This study supports the view that, although topical erythromycin is of value in the treatment of mild or moderate acne vulgaris, long established, safe and effective remedies should not be replaced by topical antibiotics until more comparative studies and investigations on bacterial resistance have been completed.

  16. In-situ photopolymerization of monodisperse and discoid oxidized methacrylated alginate microgels in a microfluidic channel

    DOE PAGES

    Wang, Shuo; Jeon, Oju; Shankles, Peter G.; Liu, Yuan; Alsberg, Eben; Retterer, Scott T.; Lee, Bruce P.; Choi, Chang Kyoung

    2016-02-03

    Here, we present a simple microfluidic technique to in-situ photopolymerize (by 365 nm ultraviolet) monodisperse oxidized methacrylated alginate (OMA) microgels using a photoinitiator (VA-086). By this technique, we generated monodisperse spherical OMA beads and discoid non-spherical beads with better shape consistency than ionic crosslinking methods do. We found that a high monomer concentration (8 w/v %), a high photoinitiator concentration (1.5 w/v %) and absence of oxygen are critical factors to cure OMA microgels. This photopolymerizing method is an alternative to current methods to form alginate microgels and is a simpler approach to generate non-spherical alginate microgels.

  17. Hydrolysis of wheat bran, rice bran and jute powder by immobilized enzymes from Macrophomina phaseolina.

    PubMed

    Roy, P K; Roy, U; Vora, V C

    1993-03-01

    The stability of cellulolytic and hemicellulolytic enzymes from Macrophomina phaseolina improved on immobilization and was 1.5 to 2-fold more active against pre-treated wheat bran, rice bran or jute powder. The hydrolysis efficiency of the catalyst increased with a decrease in its particle size. About 80% (w/v) of the sugar obtained from wheat bran was assimilated by Saccharomyces sp., whereas the corresponding values for rice bran and jute powder were about 70 and 50% (w/v), respectively.

  18. Production of D-lactic acid from sugarcane molasses, sugarcane juice and sugar beet juice by Lactobacillus delbrueckii.

    PubMed

    Calabia, Buenaventurada P; Tokiwa, Yutaka

    2007-09-01

    Lactobacillus delbrueckii was grown on sugarcane molasses, sugarcane juice and sugar beet juice in batch fermentation at pH 6 and at 40 degrees C. After 72 h, the lactic acid from 13% (w/v) sugarcane molasses (119 g total sugar l(-1)) and sugarcane juice (133 g total sugar l(-1)) was 107 g l(-1) and 120 g l(-1), respectively. With 10% (w/v) sugar beet juice (105 g total sugar l(-1)), 84 g lactic acid l(-1) was produced. The optical purities of D: -lactic acid from the feedstocks ranged from 97.2 to 98.3%.

  19. Large-Scale Purification of Peroxisomes for Preparative Applications.

    PubMed

    Cramer, Jana; Effelsberg, Daniel; Girzalsky, Wolfgang; Erdmann, Ralf

    2015-09-01

    This protocol is designed for large-scale isolation of highly purified peroxisomes from Saccharomyces cerevisiae using two consecutive density gradient centrifugations. Instructions are provided for harvesting up to 60 g of oleic acid-induced yeast cells for the preparation of spheroplasts and generation of organellar pellets (OPs) enriched in peroxisomes and mitochondria. The OPs are loaded onto eight continuous 36%-68% (w/v) sucrose gradients. After centrifugation, the peak peroxisomal fractions are determined by measurement of catalase activity. These fractions are subsequently pooled and subjected to a second density gradient centrifugation using 20%-40% (w/v) Nycodenz. PMID:26330621

  20. Measuring the turbulent wind vector with a weight-shift Microlight Aircraft

    NASA Astrophysics Data System (ADS)

    Metzger, S.; Junkermann, W.; Neidl, F.; Butterbach-Bahl, K.; Schmid, H. P.; Beyrich, F.; Zheng, X. H.; Foken, T.

    2009-09-01

    The Small Environmental Research Aircraft (SERA) D-MIFUs initial fields of application are aerosol / cloud and radiation transfer research. Therefore a comparatively slow (True Airspeed, TAS ~25 ms-1) but highly mobile microlight aircraft was envisaged. To broaden the application area of D-MIFU we explore whether the microlight can also be used for Eddy Covariance (EC) flux measurement. To obtain useful data sets for airborne EC a reliable turbulent Wind Vector (WV) measurement is a key requirement. Here we present methodology and results to calibrate and express performance and uncertainty of microlight based WV measurement. Specific attention is given to the influence of the flexible-wing weight-shift geometry on the WV measurement. For the WV measurement we equipped D-MIFU with a 70 cm long noseboom supporting a classical 5 hole probe and a fast 50 μm diameter thermocouple. An Inertial Navigation System (INS) supplies high accuracy ground speeds (Ï?=0.05 ms-1) and attitude angles (Ï?=0.03° , 0.1° respectively for heading). Data are stored with 10 Hz yielding a horizontal resolution of 2.5 m. The INS also allows to analyze aircraft dynamics such as 3d rotation rates and acceleration of the nacelle body. Further estimates for 3d acceleration of airfoil and noseboom are obtained at 100 Hz. The noseboom calibration coefficients under laboratory conditions were obtained by wind tunnel- and thermal bath measurements. To transfer these characteristics for in-flight conditions we carried out a series of flights with D-MIFU above the Boundary Layer under calm conditions. On basis of level flights at different power settings we were able to determine dynamic pressure-, sideslip- and attack angle offsets. Additionally forced maneuvers, such as e.g. phugoids, have been performed. By means of multivariate analysis these data are used to assess and minimize the impact of microlight nacelle and airfoil rapidly varying motions (RVM) on the WV components. In the final

  1. The C8 Health Project: Design, Methods, and Participants

    PubMed Central

    Frisbee, Stephanie J.; Brooks, A. Paul; Maher, Arthur; Flensborg, Patsy; Arnold, Susan; Fletcher, Tony; Steenland, Kyle; Shankar, Anoop; Knox, Sarah S.; Pollard, Cecil; Halverson, Joel A.; Vieira, Verónica M.; Jin, Chuanfang; Leyden, Kevin M.; Ducatman, Alan M.

    2009-01-01

    Background The C8 Health Project was created, authorized, and funded as part of the settlement agreement reached in the case of Jack W. Leach, et al. v. E.I. du Pont de Nemours & Company (no. 01-C-608 W.Va., Wood County Circuit Court, filed 10 April 2002). The settlement stemmed from the perfluorooctanoic acid (PFOA, or C8) contamination of drinking water in six water districts in two states near the DuPont Washington Works facility near Parkersburg, West Virginia. Objectives This study reports on the methods and results from the C8 Health Project, a population study created to gather data that would allow class members to know their own PFOA levels and permit subsequent epidemiologic investigations. Methods Final study participation was 69,030, enrolled over a 13-month period in 2005–2006. Extensive data were collected, including demographic data, medical diagnoses (both self-report and medical records review), clinical laboratory testing, and determination of serum concentrations of 10 perfluorocarbons (PFCs). Here we describe the processes used to collect, validate, and store these health data. We also describe survey participants and their serum PFC levels. Results The population geometric mean for serum PFOA was 32.91 ng/mL, 500% higher than previously reported for a representative American population. Serum concentrations for perfluorohexane sulfonate and perfluorononanoic acid were elevated 39% and 73% respectively, whereas perfluorooctanesulfonate was present at levels similar to those in the U.S. population. Conclusions This largest known population study of community PFC exposure permits new evaluations of associations between PFOA, in particular, and a range of health parameters. These will contribute to understanding of the biology of PFC exposure. The C8 Health Project also represents an unprecedented effort to gather basic data on an exposed population; its achievements and limitations can inform future legal settlements for populations exposed to

  2. 21. INTERIOR VIEW, UNDER THE MAIN FLOOR SHOWING THE LINESHAFT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. INTERIOR VIEW, UNDER THE MAIN FLOOR SHOWING THE LINESHAFT SYSTEM ONCE POWERED BY A STEAM ENGINE AND LATER BY TWO LARGE ELECTRICAL MILL MOTORS (NOTICE LARGE GEAR IN FOREGROUND) THAT OPERATED EACH NAIL MACHINE; PRESENTLY THE NAIL MACHINES ARE DRIVEN BY INDIVIDUAL ELECTRICAL MOTORS - LaBelle Iron Works, Thirtieth & Wood Streets, Wheeling, Ohio County, WV

  3. 15. INTERIOR OF POWER PLANT LOOKING SOUTHWEST. BACK SIDE OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. INTERIOR OF POWER PLANT LOOKING SOUTHWEST. BACK SIDE OF ELECTRICAL PANEL ON LEFT, AND C. 1910 GENERATOR COVER ON RIGHT. - Potomac Power Plant, On West Virginia Shore of Potomac River, about 1 mile upriver from confluence with Shenandoah River, Harpers Ferry, Jefferson County, WV

  4. General view of low pressure compressor (unit #3) with compressor ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    General view of low pressure compressor (unit #3) with compressor in foreground and engines in background. High pressure stage is on left, low pressure stage is on right. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  5. Detail view of unit 43 with high pressure stage compressor ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Detail view of unit 43 with high pressure stage compressor in left foreground and low pressure stage compressor in right background. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  6. Innovating blackberry production system

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This article provides an overview of progress made on the blackberry production system at the Appalachian Fruit Research Station in Kearneysville, WV. Several lines of research have made a significant positive impact to the blackberry industry as the new technology has have been successfully transf...

  7. 34. INTERIOR VIEW, SAME AS ABOVE WITH THE FEEDER ROD ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    34. INTERIOR VIEW, SAME AS ABOVE WITH THE FEEDER ROD BEING OFFERED INTO THE MACHINE; UNLIKE THE OTHER NAIL CUTTING MACHINES, THE NAIL PLATE MUST BE HAND FLIPPED AND HAND FED WITH THIS MACHINE - LaBelle Iron Works, Thirtieth & Wood Streets, Wheeling, Ohio County, WV

  8. Training Workers for Environmental Clean-Up Jobs.

    ERIC Educational Resources Information Center

    Baldwin, Fred

    1993-01-01

    Describes the International Union of Operating Engineers (IUOE) Hazmat Training Program (Beckley, WV). It is the largest program in the nation for training skilled workers to safely handle toxic and hazardous wastes. This program has produced more than 450 certified instructors, who, in turn, have trained more than 18,000 workers. (LP)

  9. Synthesis, kinetics and photocatalytic study of "ultra-small" Ag-NPs obtained by a green chemistry method using an extract of Rosa 'Andeli' double delight petals.

    PubMed

    Suárez-Cerda, Javier; Alonso-Nuñez, Gabriel; Espinoza-Gómez, Heriberto; Flores-López, Lucía Z

    2015-11-15

    This paper reports the effect of different concentrations of Rosa 'Andeli' double delight petals aqueous extract (PERA) in the synthesis of silver nanoparticles (Ag-NPs), using an easy green chemistry method. Its kinetics study and photocatalytic activity were also evaluated. The Ag-NPs were obtained using an aqueous silver nitrate solution (AgNO3) with 9.66% w/v, 7.25% w/v, and 4.20% w/v PERA as both reducing-stabilizing agent. The formation of the Ag-NPs was demonstrated by analysis of UV-vis spectroscopy, scanning electron microscopy-energy dispersive spectroscopy (SEM-EDS) and transmission electron microscopy (TEM). TEM analysis shows spherical nanoparticles in shape and size between ∼0.5 and 1.4nm. A comparative study was done to determine which concentration was the best reducing-stabilizing agent, and we found out that "ultra-small" nanoparticles (0.5-1.1nm) were obtained with 9.66% w/v of PERA. The size of the Ag-NPs depends on the concentration of PERA and Ag(I). The reaction of formation of "ultra-small" Ag-NPs, proved to be first order for metallic precursor (silver) and second order for reducing-stabilizing agent (PERA). The Ag-NPs showed photocatalytic activity, in degradation of commercial dye with an efficiency of 95%. PMID:26218196

  10. Intensification of enzymatic hydrolysis of waste newspaper using ultrasound for fermentable sugar production.

    PubMed

    Subhedar, Preeti B; Babu, Narmadha R; Gogate, Parag R

    2015-01-01

    An effective conversion of lignocellulose into fermentable sugars is a key step in producing bioethanol in an eco-friendly and cost effective manner. In this study, the effect of ultrasound on enzymatic hydrolysis of newspaper, a potential feedstock for bioethanol production due to its high cellulosic content, was investigated. The effect of substrate loading, enzyme loading, temperature, ultrasonic power and duty cycle on the hydrolysis has been studied. Optimum conditions for conventional enzymatic hydrolysis were substrate loading of 5% (w/v), enzyme loading of 0.14% (w/v), temperature of 323K, and under these conditions and 72h of hydrolysis, reducing sugar yield of 11.569g/L was obtained. In case of ultrasound-assisted enzymatic hydrolysis approach, optimum conditions obtained were substrate loading of 3% (w/v), enzyme loading of 0.8% (w/v), sonication power of 60W, duty cycle of 70%, hydrolysis time of 6.5h and the reducing sugar yield obtained under these conditions was 27.6g/L. Approximately 2.4 times increase in the release of reducing sugar concentration was obtained by the ultrasound-assisted enzymatic hydrolysis approach. Results indicate that there is a synergistic effect obtained from the combination of ultrasound and enzymes which lowers the diffusion-limiting barrier to enzyme/substrate binding and results in an increase in reaction rate. The experimental data were also fitted in a simple three parameter kinetic model.

  11. Water vapor permeability, mechanical, optical and sensorial properties of plasticized guar gumedible films

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Edible films were prepared by casting method using guar gum and glycerol in different ratios. The concentration of guar gum was 1.0, 1.5 and 2.0% whereas glycerol concentration was 20, 30 and 40% (w/v). The water vapor permeability (WVP), mechanical properties (tensile strength and elongation), thic...

  12. Preparation, characterization, mechanical and barrier properties investigation of chitosan-clay nanocomposites.

    PubMed

    Giannakas, Aris; Grigoriadi, Kalouda; Leontiou, Areti; Barkoula, Nektaria-Marianthi; Ladavos, Athanasios

    2014-08-01

    In the current study the effect of dilution of chitosan acetate solution and of the use of a reflux-solution method on the morphology, the mechanical and water barrier properties of chitosan based nanocomposites is being investigated. Two series of nanocomposite films from two chitosan acetate solutions with 2 w/v% and 1 w/v% in chitosan were prepared, with 3, 5 and 10 wt% Na-montmorillonite (NaMMT) and/or 30 wt% glycerol. Intercalation of NaMMT was more effective in films based on 2 w/v% solutions which presented decreased hydrated crystallinity. Upon NaMMT addition an enhancement was found in stiffness and strength (up to 100%) and a remarkable decrease in the elongation at break (up to 75%) and water vapor permeability (WVP) (up to 65%). This enhancement was less pronounced in 1 w/v% systems. Addition of glycerol had a negative effect on the stiffness, strength and WVP, and a positive effect on the elongation at break and the absorbed water. Compared with the conventional solution cast method, the reflux treatment led to a significant improvement of the tested properties of nanocomposite films. PMID:24751253

  13. Pharmacognostical and phytochemical evaluation of Vara Asanadi Kwatha.

    PubMed

    Ramachandran, Anju P; Prasad, Shyam M; Samarakoon, S M S; Chandola, H M; Harisha, C R; Shukla, V J

    2012-01-01

    Vara Asanadi Kwatha (VAK) is a compound Ayurvedic formulation prescribed in the management of obesity. Pharmacognostical study counting both macroscopic and powder microscopy of raw drug exposed the quality and genuineness of all the constituents of VAK. Organoleptic features of coarse powder made out of the crude drugs were within the standard range. Specific gravity of the decoction was 1.0185 and pH was 5.5.Total solid content present in the Kwatha was 4.525% w/v, total ash 0.949% w/v, and acid insoluble ash was 0.052% w/v. Iron assay showed the presence of Fe(2)O(3) as 0.065% w/v. Qualitative scrutiny demonstrated the presence of flavonoids and tannis. Thin Layer Chromatography (TLC) and High Performance Thin Layer Chromatography (HPTLC) were carried out after organizing appropriate solvent system in which maximum three spots were distinguished in TLC and nine spots in HPTLC and most of the R(f) values were identical when done with different sample extractive methods. This shows the presence of certain definite constituents in the decoction and is helpful for the easy separation of these constituents. PMID:23049198

  14. Phanerochaete chrysosporium IBL-03 secretes high titers of manganese peroxidase during decolorization of Drimarine Blue K2RL textile dye.

    PubMed

    Noreen, Razia; Asgher, Muhammad; Bhatti, Haq Nawaz; Batool, Shaheera; Asad, Muhammad Javaid

    2011-01-01

    A novel indigenous strain, Phanerochaete chrysosporium IBL-03, with high manganese peroxidase (MnP) activities was used for decolorization of a reactive textile dye, Drimarine Blue K2R, which is used extensively in textile units of Pakistan. The initial experiment was run for seven days with 0.01% (w/v) dye solution prepared in Kirk's basal nutrient medium. Samples were removed after every 24 h and the extent of dye decolorization was determined at lambda(max) of the dye. The study revealed that P. chrysosporium caused 65% decolorization of Drimarine Blue K2RL in seven days. By process optimization, 97% colour removal could be achieved in three days using 0.005% (w/v) Drimarine Blue K2RL solution at pH 4.0 and 30 degrees C in defined Kirk's medium with 0.9% (w/v) molasses and 0.2% (w/v) ammonium dihydrogen phosphate added as carbon and nitrogen sources, respectively. Manganese peroxidase was found to be the major enzyme (560 IU/mL) involved in dye decolorization of Drimarine Blue K2RL by P. chrysosporium. The dye adsorption studies showed that the dye initially adsorbed on fungal mats disappeared later on, possibly by the action of MnP secreted by the fungus in secondary metabolism.

  15. 76 FR 60492 - Adequacy Status of the Ohio Portion of the Huntington/Ashland Submitted Annual Fine Particulate...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-29

    ..., starting at 69 FR 40038, and we used the information in these resources in making our adequacy... AGENCY Adequacy Status of the Ohio Portion of the Huntington/Ashland Submitted Annual Fine Particulate... Ohio portion of the Huntington/Ashland WV-KY-OH area. Ohio submitted the insignificance findings...

  16. Implementation of the Master Plan for Statewide Professional Staff Development for 2011-2012: An Evaluation Study

    ERIC Educational Resources Information Center

    Hammer, Patricia Cahape

    2012-01-01

    This evaluation study examined the formation and implementation of the West Virginia Board of Education's Master Plan for Professional Staff Development for 2011-2012 (PD Master Plan). The performance of PD providers included in the PD Master Plan: Marshall University, all eight regional education service agencies (RESAs), the WV Center for…

  17. Immobilization of Erwinia sp. D12 Cells in Alginate-Gelatin Matrix and Conversion of Sucrose into Isomaltulose Using Response Surface Methodology

    PubMed Central

    Kawaguti, Haroldo Yukio; Carvalho, Priscila Hoffmann; Figueira, Joelise Alencar; Sato, Hélia Harumi

    2011-01-01

    Isomaltulose is a noncariogenic reducing disaccharide and also a structural isomer of sucrose and is used by the food industry as a sucrose replacement. It is obtained through enzymatic conversion of microbial sucrose isomerase. An Erwinia sp. D12 strain is capable of converting sucrose into isomaltulose. The experimental design technique was used to study the influence of immobilization parameters on converting sucrose into isomaltulose in a batch process using shaken Erlenmeyer flasks. We assessed the effect of gelatin and transglutaminase addition on increasing the reticulation of granules of Erwinia sp. D12 cells immobilized in alginate. Independent parameters, sodium alginate concentration, cell mass concentration, CaCl2 concentration, gelatin concentration, and transglutaminase concentration had all a significant effect (P < 0.05) on isomaltulose production. Erwinia sp. D12 cells immobilized in 3.0% (w/v) sodium alginate, 47.0% (w/v) cell mass, 0.3 molL−1 CaCl2, 1.7% (w/v) gelatin and 0.15% (w/v) transglutaminase presented sucrose conversion into isomaltulose, of around 50–60% in seven consecutive batches. PMID:21785708

  18. 16. MAN LADLING GLASS FROM POT. STEAM IS CAUSED BY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. MAN LADLING GLASS FROM POT. STEAM IS CAUSED BY WATER COOLING MOLTEN GLASS IN POT. NOTE GLASS THAT HAS POURED OVER THE SIDE OF THE POT. - Seneca Glass Company Factory, Beechurst Avenue between Sixth & Eighth Streets, Morgantown, Monongalia County, WV

  19. 2. Credit PEM. View of Martinsburg Power Company steam generating ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Credit PEM. View of Martinsburg Power Company steam generating plant. From right to left: original 1889 generating building, transformer room, new generating room and, adjacent to draft stack is boiler room addition. Photo c. 1911. - Dam No. 4 Hydroelectric Plant, Potomac River, Martinsburg, Berkeley County, WV

  20. 77 FR 30325 - Agency Information Collection Activities: Proposed Collection; Comments Requested: Notification...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-22

    ... of Alcohol, Tobacco, Firearms and Explosives Agency Information Collection Activities: Proposed... Explosives (ATF), will be submitting the following information collection request to the Office of Management... Explosives Licensing Center at Christopher.R.Reeves@usdoj.gov or 244 Needy Road, Martinsburg, WV...

  1. 9. View southeast, interior, ground floor, across area 5 towards ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    9. View southeast, interior, ground floor, across area 5 towards area 2, with area 3 at left - Abraham Cyrus Farmstead, Barn, About 160 feet south-southwest of farmhouse at 3271 Cyrus Road (County Road 1/6), Cyrus, Wayne County, WV

  2. 28 CFR 16.34 - Procedure to obtain change, correction or updating of identification records.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... PRODUCTION OR DISCLOSURE OF MATERIAL OR INFORMATION Production of FBI Identification Records in Response to... any entry on his/her record to the FBI, Criminal Justice Information Services (CJIS) Division, ATTN: SCU, Mod. D-2, 1000 Custer Hollow Road, Clarksburg, WV 26306. The FBI will then forward the...

  3. 28 CFR 16.34 - Procedure to obtain change, correction or updating of identification records.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... PRODUCTION OR DISCLOSURE OF MATERIAL OR INFORMATION Production of FBI Identification Records in Response to... any entry on his/her record to the FBI, Criminal Justice Information Services (CJIS) Division, ATTN: SCU, Mod. D-2, 1000 Custer Hollow Road, Clarksburg, WV 26306. The FBI will then forward the...

  4. 28 CFR 16.34 - Procedure to obtain change, correction or updating of identification records.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... PRODUCTION OR DISCLOSURE OF MATERIAL OR INFORMATION Production of FBI Identification Records in Response to... any entry on his/her record to the FBI, Criminal Justice Information Services (CJIS) Division, ATTN: SCU, Mod. D-2, 1000 Custer Hollow Road, Clarksburg, WV 26306. The FBI will then forward the...

  5. 28 CFR 16.34 - Procedure to obtain change, correction or updating of identification records.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... PRODUCTION OR DISCLOSURE OF MATERIAL OR INFORMATION Production of FBI Identification Records in Response to... any entry on his/her record to the FBI, Criminal Justice Information Services (CJIS) Division, ATTN: SCU, Mod. D-2, 1000 Custer Hollow Road, Clarksburg, WV 26306. The FBI will then forward the...

  6. 28 CFR 16.34 - Procedure to obtain change, correction or updating of identification records.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... PRODUCTION OR DISCLOSURE OF MATERIAL OR INFORMATION Production of FBI Identification Records in Response to... any entry on his/her record to the FBI, Criminal Justice Information Services (CJIS) Division, ATTN: SCU, Mod. D-2, 1000 Custer Hollow Road, Clarksburg, WV 26306. The FBI will then forward the...

  7. 49. INTERIOR VIEW OF HARDENER AREA SHOWING GAUGE THAT MEASURES ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    49. INTERIOR VIEW OF HARDENER AREA SHOWING GAUGE THAT MEASURES HARDNESS, THE NAIL MUST BREAK IN THE CENTER RANGE OF THE CURVED BAR TO HAVE THE CORRECT HARDNESS (THE NAIL WILL BREAK TOO EASILY IF TOO HARD AND WILL BEND TOO MUCH IF TOO SOFT) - LaBelle Iron Works, Thirtieth & Wood Streets, Wheeling, Ohio County, WV

  8. Optimization of Freeze Drying Conditions for Purified Pectinase from Mango (Mangifera indica cv. Chokanan) Peel

    PubMed Central

    Mehrnoush, Amid; Mustafa, Shuhaimi; Yazid, Abdul Manap Mohd

    2012-01-01

    Response surface methodology (RSM) along with central composite design (CCD) was applied to optimize the freeze drying conditions for purified pectinase from mango (Mangifera indica cv. Chokanan) peel. The effect of pectinase content (−2.66, 62.66 mg/mL), Arabic gum (−1.21, 10.21%, w/v), and maltodextrin (0.73, 7.26%, w/v) as independent variables on activity, yield, and storage stability of freeze-dried enzyme was evaluated. Storage stability of pectinase was investigated after one week at 4 °C and yield percentage of the enzyme after encapsulation was also determined. The independent variables had the most significant (p < 0.05) effect on pectinase activity and yield of the enzyme. It was observed that the interaction effect of Arabic gum and maltodextrin improved the enzymatic properties of freeze-dried pectinase. The optimal conditions for freeze-dried pectinase from mango peel were obtained using 30 mg/mL of pectinase content, 4.5 (%, w/v) of Arabic gum, and 4 (%, w/v) of maltodextrin. Under these conditions, the maximum activity (11.12 U/mL), yield (86.4%) and storage stability (84.2%) of encapsulated pectinase were achieved. PMID:22489134

  9. 1. Photocopy of map (from The Virginia Springs, and the ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    1. Photocopy of map (from The Virginia Springs, and the Springs of the South and West by Moorman) No date 'MAP OF ROUTES AND DISTANCES TO THE VIRGINIA SPRINGS' - White Sulphur Springs, U.S. Route 60, White Sulphur Springs, Greenbrier County, WV

  10. 77 FR 46153 - Qualification of Drivers; Exemption Applications; Vision

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-02

    ... Federal Register on January 17, 2008 (73 FR 3316), or you may visit http://edocket.access.gpo.gov/2008/pdf...) Walter O. Connelly (WA) Stephen B. Copeland (GA) Armando P. D'Angeli (PA) Donald R. Davis (FL) Louis A...) Andrew C. Kelly (WV) Jason W. King (MT) James T. Leek (WA) Billy J. Lewis (LA) Larry McCoy, Sr....

  11. 77 FR 29447 - Qualification of Drivers; Exemption Applications; Vision

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-17

    ... Federal Register on January 17, 2008 (73 FR 3316), or you may visit http://edocket.access.gpo.gov/2008/pdf.... Allen (OR) James C. Askin (FL) Ernie E. Black (NC) Gary O. Brady (WV) Stephen H. Goldcamp (OH) Hazel L. Hopkins, Jr. (MD) Wai F. King (IL) Dennis E. Krone (IL) Richard J. McKenzie, Jr. (MD) Christopher...

  12. Effect of some antioxidants on the color change of white lotion.

    PubMed

    Boonme, P

    2000-01-01

    The purpose of this study was to improve the physical color stability of official white lotion to a point where a freshly prepared lotion would not be necessary. Three anioxidants (ascorbic acid, sodium metabisulfite and sodium sulfite) were added into official white lotion in a concentration of 0.1% w/v. Sodium sulfite was found to be the most suitable.

  13. 34. Credit JTL. Second floor, view of Monarch Co. Corn ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    34. Credit JTL. Second floor, view of Monarch Co. Corn cracking machine, by Sprout, Waldron and Co., (Muncy, PA), which cut and diced corn to a uniform size, then separated it into three grades of cracked corn and corn meal and removed chaff. - Bunker Hill Mill, County Route 26, Bunker Hill, Berkeley County, WV

  14. View southsouthwest, buildings of the succeeding farmstead. (Left to right: ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View south-southwest, buildings of the succeeding farmstead. (Left to right: Abraham J. Cyrus, Jr.'s house, pool pump house, hen house converted to garage, chicken house, equipment shed, barn) - Abraham Cyrus Farmstead, 3271 Cyrus Road (County Road 1/6), Cyrus, Wayne County, WV

  15. View southwest, buildings of the Abraham Cyrus Farmstead. (Left to ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    View southwest, buildings of the Abraham Cyrus Farmstead. (Left to right in photograph: hen house, chicken shed, equipment shed, large tree at center foreground, barn, evergreen in yard, wash house, farmhouse - Abraham Cyrus Farmstead, 3271 Cyrus Road (County Road 1/6), Cyrus, Wayne County, WV

  16. Comparison between WorldView-2 and SPOT-5 images in mapping the bracken fern using the random forest algorithm

    NASA Astrophysics Data System (ADS)

    Odindi, John; Adam, Elhadi; Ngubane, Zinhle; Mutanga, Onisimo; Slotow, Rob

    2014-01-01

    Plant species invasion is known to be a major threat to socioeconomic and ecological systems. Due to high cost and limited extents of urban green spaces, high mapping accuracy is necessary to optimize the management of such spaces. We compare the performance of the new-generation WorldView-2 (WV-2) and SPOT-5 images in mapping the bracken fern [Pteridium aquilinum (L) kuhn] in a conserved urban landscape. Using the random forest algorithm, grid-search approaches based on out-of-bag estimate error were used to determine the optimal ntree and mtry combinations. The variable importance and backward feature elimination techniques were further used to determine the influence of the image bands on mapping accuracy. Additionally, the value of the commonly used vegetation indices in enhancing the classification accuracy was tested on the better performing image data. Results show that the performance of the new WV-2 bands was better than that of the traditional bands. Overall classification accuracies of 84.72 and 72.22% were achieved for the WV-2 and SPOT images, respectively. Use of selected indices from the WV-2 bands increased the overall classification accuracy to 91.67%. The findings in this study show the suitability of the new generation in mapping the bracken fern within the often vulnerable urban natural vegetation cover types.

  17. Mutants of the pentose-fermenting yeast Pachysolen tannophilus tolerant to hardwood spent sulfite liquor and acetic acid.

    PubMed

    Harner, Nicole K; Bajwa, Paramjit K; Habash, Marc B; Trevors, Jack T; Austin, Glen D; Lee, Hung

    2014-01-01

    A strain development program was initiated to improve the tolerance of the pentose-fermenting yeast Pachysolen tannophilus to inhibitors in lignocellulosic hydrolysates. Several rounds of UV mutagenesis followed by screening were used to select for mutants of P. tannophilus NRRL Y2460 with improved tolerance to hardwood spent sulfite liquor (HW SSL) and acetic acid in separate selection lines. The wild type (WT) strain grew in 50 % (v/v) HW SSL while third round HW SSL mutants (designated UHW301, UHW302 and UHW303) grew in 60 % (v/v) HW SSL, with two of these isolates (UHW302 and UHW303) being viable and growing, respectively, in 70 % (v/v) HW SSL. In defined liquid media containing acetic acid, the WT strain grew in 0.70 % (w/v) acetic acid, while third round acetic acid mutants (designated UAA301, UAA302 and UAA303) grew in 0.80 % (w/v) acetic acid, with one isolate (UAA302) growing in 0.90 % (w/v) acetic acid. Cross-tolerance of HW SSL-tolerant mutants to acetic acid and vice versa was observed with UHW303 able to grow in 0.90 % (w/v) acetic acid and UAA302 growing in 60 % (v/v) HW SSL. The UV-induced mutants retained the ability to ferment glucose and xylose to ethanol in defined media. These mutants of P. tannophilus are of considerable interest for bioconversion of the sugars in lignocellulosic hydrolysates to ethanol.

  18. Biological abatement of cellulase inhibitors

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Bio-abatement uses a fungus to metabolize and remove fermentation inhibitors. To determine whether bio-abatement could alleviate enzyme inhibitor effects observed in biomass liquors after pretreatment, corn stover at 10% (w/v) solids was pretreated with either dilute acid or liquid hot water. The ...

  19. 16. GENERAL VIEW FROM TAILRACE OF CONSTRUCTION OF NEW POWER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. GENERAL VIEW FROM TAILRACE OF CONSTRUCTION OF NEW POWER HOUSE. NOTE USE STEAM PUMPS FOR REMOVING WATER FROM EXCAVATION AREA AND PORTABLE STEAM ENGINE FOR OPERATING AIR COMPRESSORS, c. 1918. - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  20. Optimization of freeze drying conditions for purified pectinase from mango (Mangifera indica cv. Chokanan) peel.

    PubMed

    Mehrnoush, Amid; Mustafa, Shuhaimi; Yazid, Abdul Manap Mohd

    2012-01-01

    Response surface methodology (RSM) along with central composite design (CCD) was applied to optimize the freeze drying conditions for purified pectinase from mango (Mangifera indica cv. Chokanan) peel. The effect of pectinase content (-2.66, 62.66 mg/mL), Arabic gum (-1.21, 10.21%, w/v), and maltodextrin (0.73, 7.26%, w/v) as independent variables on activity, yield, and storage stability of freeze-dried enzyme was evaluated. Storage stability of pectinase was investigated after one week at 4 °C and yield percentage of the enzyme after encapsulation was also determined. The independent variables had the most significant (p < 0.05) effect on pectinase activity and yield of the enzyme. It was observed that the interaction effect of Arabic gum and maltodextrin improved the enzymatic properties of freeze-dried pectinase. The optimal conditions for freeze-dried pectinase from mango peel were obtained using 30 mg/mL of pectinase content, 4.5 (%, w/v) of Arabic gum, and 4 (%, w/v) of maltodextrin. Under these conditions, the maximum activity (11.12 U/mL), yield (86.4%) and storage stability (84.2%) of encapsulated pectinase were achieved. PMID:22489134

  1. Caries Experience Differs between Females and Males across Age Groups in Northern Appalachia.

    PubMed

    Shaffer, John R; Leslie, Elizabeth J; Feingold, Eleanor; Govil, Manika; McNeil, Daniel W; Crout, Richard J; Weyant, Robert J; Marazita, Mary L

    2015-01-01

    Sex disparities in dental caries have been observed across many populations, with females typically exhibiting higher prevalence and more affected teeth. In this study we assessed the sex disparities in two Northern Appalachian populations from West Virginia (WV, N = 1997) and Pennsylvania (PA, N = 1080) by comparing caries indices between males and females across four phases of dental development: primary dentition in children aged 1-5 years, mixed dentition in children aged 6-11 years, permanent dentition in adolescents aged 12-17 years, and permanent dentition in adults aged 18-59 years. No significant sex differences were observed for children aged 1-5 years. Contrary to national and international trends, WV girls aged 6-11 years had 1.5 fewer affected teeth than boys (p < 0.001). However, by ages 12-17, caries indices in the WV girls matched those in boys. In both WV and PA adults, women and men had similar total counts of affected teeth (i.e., DMFT), although women had more dental restorations (p < 0.001) and men had more current decay (p < 0.001). These results suggest that in some Appalachian populations, young girls benefit from protection against caries that is lost during adolescence and that adult women utilize dental health care to a greater degree than men. PMID:26106416

  2. 76 FR 41411 - West Virginia Regulatory Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-14

    ... opportunity for public comment and gave the comment due date and tentative hearing date. The summary and... effective date. DATES: The interim final rule published at 76 FR 37996 is effective July 14, 2011. ADDRESSES: You may submit comments on the interim rule WV-117-FOR (76 FR 37996; June 29, 2011) by any of...

  3. Ethanol and co-product generation from pressurized batch hot water pretreated T85 bermudagrass and Merkeron napiergrass using recombinant Escherichia coli as biocatalyst

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Pretreatment of grasses is required to maximize ethanol yield during fermentation. T85 bermudagrass and Merkeron napiergrass (Pennisetum purpureum Schumach.) were either left untreated or were pressurized batch hot water (PBHW) pretreated for 2 minutes at 230°C at 5% w/v whole grass solids loading. ...

  4. 3. DETAIL OF INVERTED MINE LOCOMOTIVE OR "MOTOR," USED FOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    3. DETAIL OF INVERTED MINE LOCOMOTIVE OR "MOTOR," USED FOR SURFACE HAULAGE OF MINE CARS, LOOKING SOUTHWEST; NOTE GEARING - Nuttallburg Mine Complex, Main Mine, North side of New River, 2.7 miles upstream from Fayette Landing, Lookout, Fayette County, WV

  5. Through-vial impedance spectroscopy of critical events during the freezing stage of the lyophilization cycle: the example of the impact of sucrose on the crystallization of mannitol.

    PubMed

    Arshad, Muhammad Sohail; Smith, Geoff; Polygalov, Eugene; Ermolina, Irina

    2014-08-01

    The aim of this work was to evaluate the application of through-vial impedance spectroscopy in the measurement of eutectic crystallization during the freezing stage of the lyophilisation cycle. Impedance measurements of various sugar solutions (mannitol 5%, 10% and 15% w/v, sucrose 5% w/v and mannitol 5% w/v, and sucrose 5% w/v solutions) were taken during a freeze-thaw cycle, over a frequency range 10-10(6) Hz with a scan interval of 1.5 min, using measurement vials with externally attached electrodes connected to a high resolution impedance analyzer. Estimates for the electrical resistance of the mannitol solutions record the exothermic crystallization of mannitol at a temperature of -24 °C during the temperature ramp down stage of the freezing cycle, which is in close agreement with the off-line DSC measurement of -22 °C. The freezing profile of a 5% mannitol solution with 5% sucrose (a component that does not crystallize in the frozen solution) demonstrated the inhibition of mannitol crystallization (with the implication that the product will then require sub-Tg' freezing and drying). The work suggests a role for through-vial impedance spectroscopy in the concurrent development of the product formulation and freeze drying cycle without the uncertainty introduced when using off-line date to define the critical process parameters.

  6. Exterior view looking north/northeast with pumphouse in the center background. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Exterior view looking north/northeast with pumphouse in the center background. Piping in left foreground carries gas from other equitable facilities that is being pumped along the equitable system by the Burnsville Station. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  7. EXTERIOR VIEW LOOKING NORTH/NORTHEAST WITH PUMPHOUSE IN THE CENTER BACKGROUND. ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    EXTERIOR VIEW LOOKING NORTH/NORTHEAST WITH PUMPHOUSE IN THE CENTER BACKGROUND. PIPING IN LEFT FOREGROUND CARRIES GAS FROM OTHER EQUITABLE FACILITIES THAT IS BEING PUMPED ALONG THE EQUITABLE SYSTEM BY THE BURNSVILLE STATION. - Burnsville Natural Gas Pumping Station, Saratoga Avenue between Little Kanawha River & C&O Railroad line, Burnsville, Braxton County, WV

  8. Methanol-induced chain termination in poly(3-hydroxybutyrate) biopolymers: molecular weight control

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A systematic study was performed to demonstrate the impact of methanol (MeOH) on poly(3-hydroxybutyrate) (PHB) synthesis and molecular weight (MW) control. Glycerine (init. conc. = 1.0%; w/v), was used as the primary carbon source in batch-culture fermentations with varying concentrations (0 to 0.85...

  9. Inferring Causes of Biological Impairment in the Clear Fork Watershed, West Virginia (Final)

    EPA Science Inventory

    The Clear Fork, WV case study illustrates a causal assessment in a watershed using the USEPA stressor identification process described on www.epa.gov/caddis. This case study demonstrates that a watershed-wide causal assessment has several advantages for making analysis practical,...

  10. Protective actions of green tea polyphenols and alfacalcidol on bone microstructure in female rats with chronic inflammation

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This study investigated the effects of green tea polyphenols (GTP) and alfacalcidol on bone microstructure and strength along with possible mechanisms in rats with chronic inflammation. A 12-week study using a 2 (no GTP vs. 0.5%, w/v GTP in drinking water) × 2 (no alfacalcidol vs. 0.05 ug/kg alfacal...

  11. 75 FR 69063 - Extension of the Period for Preparation of the Clean Water Act Section 404(c) Final Determination...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-10

    ... and Consultation Concerning the Spruce No. 1 Mine, Logan County, WV AGENCY: Environmental Protection... with construction of the Spruce No. 1 Surface Mine in Logan County, West Virginia. The transmission of... over the Spruce 1 permit until February 22, 2011. FOR FURTHER INFORMATION CONTACT: Mr. David...

  12. 51. Photocopy of photograph, October 16, 1942. VIEW, LOOKING DOWNSTREAM, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    51. Photocopy of photograph, October 16, 1942. VIEW, LOOKING DOWNSTREAM, OF POWER HOUSE DURING FLOOD. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files, Dam NO. 5 listing) - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  13. 58. Photocopy of photograph, no date. VIEW OF GENERATOR UNIT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    58. Photocopy of photograph, no date. VIEW OF GENERATOR UNIT 2. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files, Properties-Buildings and Equipment listing) - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  14. 49. Photocopy of photograph, October 22, 1933. VIEW OF POWER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    49. Photocopy of photograph, October 22, 1933. VIEW OF POWER HOUSE, FOREBAY AND RIVER. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files, Dam No. 5 listing) - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  15. 37. Photocopy of photograph, c.1930. FOREBAY (WEST) ELEVATION. NOTE ABSENCE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    37. Photocopy of photograph, c.1930. FOREBAY (WEST) ELEVATION. NOTE ABSENCE OF MONITORS. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files, Dam No. 5 listing) - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  16. 46. Photocopy of photograph, c. 1933. VIEW OF DAM AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    46. Photocopy of photograph, c. 1933. VIEW OF DAM AND FOREBAY. NOTE ALL WATER FLOWING THROUGH FOREBAY AND OUT EITHER TAILRACE OR SLUICE GATE (INSTEAD OF OVER DAM) BECAUSE OF LOW WATER FLOW. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files, Dam No. 5 listing - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  17. 2. Photocopy of photograph, c. 1904. VIEW OF TAILRACE ELEVATION ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. Photocopy of photograph, c. 1904. VIEW OF TAILRACE ELEVATION OF ORIGINAL MARTINSBURG POWER COMPANY POWER HOUSE AT DAM NO. 5. (Courtesy of the Potomac Edison Company Library, Historical Data Files, Dam No. 5 listing) - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  18. 57. Photocopy of photograph, c. 1946. DETAIL OF GENERATOR UNIT ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    57. Photocopy of photograph, c. 1946. DETAIL OF GENERATOR UNIT 2, GOVERNOR, AND SWITCHBOARD. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files, Dam No. 5 listing) - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  19. 50. Photocopy of photograph, April 27, 1937. VIEW OF POWER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    50. Photocopy of photograph, April 27, 1937. VIEW OF POWER HOUSE AND SUBSTATION DURING FLOOD. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files, Dam No. 5 listing) - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  20. 44. Photocopy of photograph, October 20, 1933. VIEW OF FOREBAY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    44. Photocopy of photograph, October 20, 1933. VIEW OF FOREBAY AND INLET OPENINGS, NOTE SLUICE GATE AND DAM AT LOWER RIGHT. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files, Dam No. 5 listing) - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV