Sample records for aarne luud kalle

  1. Shaping Strategic Defense: The Air Force Nuclear Mission

    DTIC Science & Technology

    2009-01-01

    Strike Command. Washington DC: Department of the Air Force. Kall , Rob. June 20, 2008. “Pentagon: Over 1000 Nuclear Weapons Parts Missing?” http...www.huffingtonpost.com/rob- kall /pentagon-over-1000-nuclea_b_108225.html (accessed December 16, 2008). Rolfsen, B. November 6, 2007. http...16, 2008). 6 Schlesinger. 7 Kall , Rob. June 20, 2008. “Pentagon: Over 1000 Nuclear Weapons Parts Missing?” http://www.huffingtonpost.com/rob- kall

  2. The Tactical Center of Gravity: How Useful is the Concept?

    DTIC Science & Technology

    1990-01-06

    through the Huertgen Forest, across the Kall River, capture the town of Kommerscheidt, and then capture Schmidt. The regiment also was required to protect...south through the woods, cross country to the Kall River, to take Kommerscheidt. The 3rd Battalion was to follow the 1st Battalion and take Schmidt on...desperate struggle. The lead battalions were destroyed piecemeal by the Germans in Kommerscheidt and Schmidt and along the Kall Trail. Poor

  3. Quantitative Infrared Spectroscopic Measurements of Boron Fluorides.

    DTIC Science & Technology

    1980-08-01

    F49620-77-C-0075 Gozewski, S. Kallelis , J.C. Wormhoudt, L.M. Pete rson* I PERFORMING ORGANIZATION NAME AND ADDRESS 10. PROGRAM ELEMENT. PROJECT...S.Aernstein. Joel A.Ailverl Wite d- Brown onrad 1. Gozewski, Spiros Kallelis , Joda C. Wormhoudt / t "and Lauren M. Peterson* Center for Chemical and...Joel A. Silver, Mark S. Zahniser, Charles E. Kolb, Robert G. Brown, Conrad M. Gozewski, Spiros Kallelis , and Joda C. WormhoudtI I ABSTRACT A high

  4. A Battalion Staff Prepared for War: The Key to Combined Arms Success on the Modern Tactical Battlefield,

    DTIC Science & Technology

    1988-03-10

    comoat sunort Droblems put the 3d Battalion in a Drecarious Dosition On 4 November. First, the Kall River trail, the major route from the division to...was to maintain one- way traffic through to the Kall River bridge while Company A did the same from the bridge to Schmidt. C Company, in reserve...supply weasels from the 3d Battalion crossed the Kall . (52) Meanwhile, in Schmidt the 3d Battalion prepared to defend. * The battalion had no combined arms

  5. Engineered Resilient Systems: Knowledge Capture and Transfer

    DTIC Science & Technology

    2014-08-29

    development, but the work has not progressed significantly. 71 Peter Kall and Stein W. Wallace, Stochastic Programming, John Wiley & Sons, Chichester, 1994...John Wiley and Sons: Hoboken, 2008. Peter Kall and Stein W. Wallace, Stochastic Programming, John Wiley & Sons, Chichester, 1994. Rhodes, D.H., Lamb

  6. Using Generalized Annotated Programs to Solve Social Network Diffusion Optimization Problems

    DTIC Science & Technology

    2013-01-01

    as follows: —Let kall be the k value for the SNDOP-ALL query and for each SNDOP query i, let ki be the k for that query. For each query i, set ki... kall − 1. —Number each element of vi ∈ V such that gI(vi) and V C(vi) are true. For the ith SNDOP query, let vi be the corresponding element of V —Let...vertices of S. PROOF. We set up |V | SNDOP-queries as follows: —Let kall be the k value for the SNDOP-ALL query and and for each SNDOP-query i, let ki be

  7. Investigation into the Distribution of Ballast Water Tracers in Coastal Waters

    DTIC Science & Technology

    2009-11-01

    terrestrial and marine vegetation ( Kalle , 1966; Sieberth, 1969; Stabenau et al., 2004), microbial productivity in the water column (Nelson et al...London. Kalle , K., 1966. The problem of the Gelbstoffe in the sea. Oceanogr. Mar. Biol. Ann. Review, 4: 91-104. Lackowicz, J., 1999. Principles of

  8. Towards DNA-Based Programmable Matter

    DTIC Science & Technology

    2012-02-28

    optics. Nature 2003, 424, 824–830. (2) Xu, H. X.; Bjerneld, E. J.; Kall , M.; Borjesson, L. Spectroscopy of single hemoglobin molecules by surface...Brenner, M. P.; Manoharan, V. N. The Free-energy Landscape of Clusters of Attractive Hard Spheres. Science 2010, 327, 560–563. (35) Xu, H. X.; Kall , M

  9. Quantitative and Qualitative Prediction of Light Absorption by Colored Dissolved Organic Matter in the Coastal Zone

    DTIC Science & Technology

    2008-01-01

    North Sea region CDOM has been shown to behave quasi conservatively and be a useful tracer of water mass mixing ( Kalle 1949; Højerslev 1988...Project started in 2005 and ended in 2007, with a budget of 1.4 million DKK (approx. US$230,000). REFERENCES Kalle K. 1949. Fluoreszenz und

  10. Reduced-Order Observer Model for Antiaircraft Artillery (AAA) Tracker Response

    DTIC Science & Technology

    1979-08-01

    a22 -ka1 2) z + (a22 - ka1 2) ky + (a21 - kall ) y + (b2 - kb) uc (10) Next, the actual output of this model is expressed as the sum of the output u...a22x2 + b2u + f2eT = (a2 2 - kal2) z + (a2 2 - ka12) ky + (a21 - kall ) y + (b2 - kb l ) uc u=u +vC [Ti Y2] [y] By introducing new variables: X3 = x2...x3 [(a22- ka2)k + (a2- kall ) - (b2- kb) (YI + kY2) Y + [a22 - ka12 - (b2 - kbl) Y2] X3 + (b2 -kbl) y2 e + (2 - kbI) v + (f2 - kfl) 0 T e = (a22- ka12

  11. Analysis of Fleet Reports of Bioluminescence in the Indian Ocean

    DTIC Science & Technology

    1981-12-14

    Kalle [ 20,21], who theorized that they were caused by seismic disturbances. According to his theory, such disturbances would produce wheels in...Whether this phenomenon is the same as that described by Kalle is uncertain. The description of the phosphorescent wheel, however, was truly classic. The...Luciferin in Some Shallow-Water FisheF Comp. Biochem. Physiol. 40A:163-179, 1971 . 14. P. J. Herring, "Observations of Bioluminescence at Sea," Mar. Obs. 46

  12. Second Analysis of Fleet Reports of Bioluminescence in the Indian Ocean.

    DTIC Science & Technology

    1983-12-15

    9. K . Kalle , "Die ritselhafte und unheimliche Naturerscheinung des ’explodierenden’ und des ’rotierenden’ Meeresleuchtens-eine Folge lokaler Seebeben...34 Deutsche Hydrog. Zets. 13, 49-77 (1960). 10. K . Kalle , "Wheels of Light," Sea Frontiers 15(2), 116-122 (1969). f a ** . . . . . . . ~ ... - VI. ISM ...Special \\roti ’ I , ~ ~ ~ ~ ~ ~ %WT- 2.7%,: 7% l. * , ,- .. I.’ - 1 . ’%- , . • ’- 17-* -’ k - - ’. -’ SECOND ANALYSIS OF FLEET REPORTS OF

  13. Marine Particulate Absorption Techniques and Applications in the Study of Inherent and Apparent Optical Properties of the Ocean

    DTIC Science & Technology

    1992-01-01

    Meteortpl.. 24. 193-205. 1985. Bricaud. . . Morel, and L. Prieur. Absorption by dissolved Kalle . K .. What do we know about the ’Glso’. nor.10...Oceanogr.. 26. 43-53. 1991. Kalle . K .. The problem of Gelbstoff in the sea. Oceanogr. Mar. Bricaud..5A. Morel, and L. Prieur. Optical efficiency factors of...with report. Carder, K . L, S. K . Hawes, K . A. Baker, R. C. Smith, R. G. Steward, B. G. Mitchell. 1991. Reflectance model for quantifying chlorophyll a

  14. Potential of Remote Sensing in the Corps of Engineers Dredging Program.

    DTIC Science & Technology

    1985-11-01

    remotely sensed sultispectral data. Earth Resources Survey Symposium June 9-12, Houston. Texas. Lyndon B. Johnson Space Center, pp. 2087-2098. Kalle , K ...a" -- , :0 0 4 n - 0 00 0 𔃾A 14. U ,U a4 t4 f"’ 4- t4- -- cf 0 0-4 z so a 0 . 4," . +" ’," - AC8" N N- ,, . -o - o 0 0 - 4.4 o o 0’, K . 0...signal. Several studies have shown that many substances can be identified by their optical properties. Using cruise data, Kalle (1966) was one of the

  15. Urinary coagulation-fibrinolysis, kallirein-kinin systems and kininase in cases of preclampsia.

    PubMed

    Mutoh, S; Kobayashi, M; Hirata, J; Itoh, N; Maki, M; Komatsu, Y; Yoshida, A; Sasa, H; Kuroda, K; Kikuchi, Y

    1992-01-01

    Urinary kallikrein and kallikrein activity significantly decreased in cases of preeclampsia (u-kall./CRE.index 42.39 +/- 9.66 ng/mg, u-kall. act./CRE.index 0.26 +/- 0.06 ng/min/mg), and urinary kininase II and kininase activity significantly increased (u-kininase/CRE.index 10.91 +/- 1.26 x 10(-3) IU/min/mg, u-kininase act./CRE.index 506.37 +/- 178.45 pg/min/mg) when compared with those of normal gravidas from 28 weeks to 42 weeks of gestation (u-kall./CRE.index 189.31 +/- 14.17 ng/mg, u-kall. act./CRE index 1.08 +/- 0.10 ng/min/mg, u-kininase/CRE.index 6.24 +/- 0.31 x 10(-3) IU/min/mg, u-kininase act./CRE.index 15.64 +/- 0.10 pg/min/mg). Urinary FPA, B beta 5-42, alpha 2-PI, and alpha 2PI-plasmin-complex (PIC) significantly increased in preeclampsia (u-FPA/CRE.index 23.59 +/- 8.47 ng/mg, u-B beta/CRE.index 105.26 +/- 29.30 ng/mg, u-alpha 2PI/CRE.index 121.53 +/- 43.57 ng/mg, u-PIC/CRE index 278.39 +/- 60.50 ng/mg) when compared with those of normal control group (u-FPA/CRE.index 0.92 +/- 0.04 ng/mg, u-B beta/CRE.index 12.15 +/- 0.44 ng/mg, u-alpha 2PI/CRE.index 4.18 +/- 0.33 ng/mg, u-PIC/CRE.index 5.98 +/- 1.15 ng/mg). Urinary urokinase markedly increased and urinary D-dimer was detected in severe cases of preeclampsia (u-UK/CRE.index 58.20 +/- 43.69 ng/mg, u-D-dimer 54.76 +/- 9.89 ng/ml) when compared with those of normal control group. These findings suggest that deficiency in urinary kinin excretion may induce hypertension in addition to the changes of urinary coagulation-fibrinolysis system that represents the occurrence of either the endothelial cell injury in the glomerulus or the renal tulbular damage in mild cases of preeclampsia, eventually resulting in the intra-renal vascular coagulation.

  16. Examination of Cement Pastes Hydrated Phases, and Synthetic Products by X-Ray Diffraction

    DTIC Science & Technology

    1972-04-01

    International Union o, Crystallography Commission on Crystallo- graphic Data, Powder Data, Journal of Applied Crystallography, Vol 4, pp 81-86, 1971 . 21...Papes, Research Series 1, Building Research Station, 1962. 25. l,, Dosch, Rbntgen-Ceinstrukturuntersuchu , luftemp’indlicher pulverprlparate, Zement- Kall

  17. A Critical Comparison of Some Methods for Interpolation of Scattered Data

    DTIC Science & Technology

    1979-12-01

    because faster evaluation of the local interpolants is possible. KAll things considered, the method of choice here seems to be the Modified Quadratic...topography and other irregular surfaces," J. of Geophysical Research 76 ( 1971 ) 1905-1915I’ [23) HARDY, Rolland L. - "Analytical topographic surfaces by

  18. Conducting Studies of Transfer of Learning: A Practical Guide

    DTIC Science & Technology

    1982-01-01

    X) = percent transfer (If learning C where: Kall aicrage of grades assigned to experimental :.ttmdents for p~erformlanlce in the aircraft. an average...effectiveness. Human Factors. 1971 . 13(6). 561-567. Roscoe, S.N. A little more on incremental transfer effectiveness. Human Factors. 1972, 14(4), 363-364

  19. Sublinear Upper Bounds for Stochastic Programs with Recourse. Revision.

    DTIC Science & Technology

    1987-06-01

    approximation procedures for (1.1) generally rely on discretizations of E (Huang, Ziemba , and Ben-Tal (1977), Kall and Stoyan (1982), Birge and Wets...Wright, Practical optimization (Academic Press, London and New York,1981). C.C. Huang, W. Ziemba , and A. Ben-Tal, "Bounds on the expectation of a con

  20. Coherent Plasmon-Exciton Coupling in Silver Platelet-J-aggregate Nanocomposites

    DTIC Science & Technology

    2015-02-27

    2011, 11, 1556−1560. (12) Zengin, G.; Johansson, G.; Johansson, P.; Antosiewics, T. J.; Kall , M.; Shegai, T. Sci. Rep. 2013, 3 (3074), 1−8. (13...Mater. 2005, 17, 412−415. (21) Davydov, A. S. Theory of Molecular Excitons; Plenum Press: New York, 1971 . (22) Van Burgel, M.; Wiersma, D. A.; Duppen, K

  1. The Transient Excitation and Oscillation Testing Technique Applied to a Captive Model.

    DTIC Science & Technology

    1981-06-01

    8217Kall io I 9. PERFORMING ORGANIZATION NAME AND ADDRESS PROGRAM ELEMENT. PROJECT, TASK David W. Tayl.or Naval Ship Research and -OW UNIT NUMBERS...corrective tare terms (C’. 11 C35’ C 53 and C 55) used in calculating the nondimensional oscillat ion coff ticient s. Figures 7--14 contain comparisons of

  2. Numerical and Experimental Investigation of Multiple Shock Wave/Turbulent Boundary Layer Interactions in a Rectangular Duct

    DTIC Science & Technology

    1988-01-06

    the bottom % kall followin,, the interaction. At 6Wuh = 0.35 the shock train would not stay attached to a single wall long enough for the surface...Interaction of a Shock Wave with a Laminar Boundary Layer," Lecture Notes in Physics, Vol. 8, Springer-Verlag, 1971 , pp. 151-163. 51 MacCormack, R. W

  3. Forecast of Future Ohio River Basin, Waterway Traffic Based on Shippers Surveys.

    DTIC Science & Technology

    1979-09-01

    pattern. Analytic Tool: SPSS KAll of the editing, generation of tables, graphing, and other com- putational activities were carried out through the use...00O’s) 1976-1g90 Group 1971 1990 (%) 1976 190 (9) Coal & Coke 0 0 0 1,617 3,231 +100 Petroleum Fuels 705 779 +10 509 509 +0 Aggregates 0 0 0 450 688

  4. STAMMER2 Production System for Tactical Situation Assessment. Volume 2. Code.

    DTIC Science & Technology

    1979-10-01

    1961 (WITHINR * [NLAMBDA L (*NOBIND ൖ-Nov-78 19:25") (NCONC WITHINRFNS L) (MAKEFILE (QUOTE WITHINR.LSP]) [ 1971 (CROSSPATHS [LAMBDA (Si S2 TI T2)V...176 46. 1 I 1 FKACS 47. 1 I FKSYM (221 48. 1 FKIDPB 49. I M KALL (9) 50. 1 DSPTTY FKCALL (9) 51. I 1 FKJSYS (3) 52. 1 1 1 DSPTTYSTR DECSAMEDIGITS {bl

  5. Installation Restoration Program. Phase II - Confirmation/Quantification. Stage 1 for American Lake Garden Tract, Washington.

    DTIC Science & Technology

    1985-12-20

    Kalles . 1976. Evaporation rates of methylene chloride, chloroform, 1,1,1-trichloroethane, trichloroethylene, tetrachoroethylene, and other chlorinated...State University (1969) M.S., Geology, University of Washington ( 1971 ) . . Ph.D., University of Washington (1979) " EXPERIENCE 1984 to Date Senior...ducted environmental assessments for Pacific Northwest construc- tion projects. L- 1971 Project Geologist, SEREM of Alaska (BRGM-France). Responsibil

  6. Inventory of Archaeological and Historical Resources Lava Flow Control Study, Hilo, Hawaii,

    DTIC Science & Technology

    1979-05-01

    amale- p 11111 S.PIaN. Sitea card; hial. 1971 :2 aa. INVENTRh Y OF AIIAj4AOLGICAL AND HISIORICAL ESItIMCES Sit umber Site Ded𔃻ption e Period Coed...liaison. 1932:294 SO-a-Al-ST Kalled , paved 4 PPI.Site Card; NHudson, 1932:29S.2W6 terraced platorm bo-Li-AI. 55$ Legendary crevite, Esrsaa% 1903:Is

  7. The accuracies of DNA-based estimates of genetic merit derived from Angus or multibreed beef cattle training populations.

    PubMed

    Weber, K L; Drake, D J; Taylor, J F; Garrick, D J; Kuehn, L A; Thallman, R M; Schnabel, R D; Snelling, W M; Pollak, E J; Van Eenennaam, A L

    2012-12-01

    Several organizations have developed prediction models for molecular breeding values (MBV) for quantitative growth and carcass traits in beef cattle using Bovine SNP50 genotypes and phenotypic or EBV data. Molecular breeding values for Angus cattle have been developed by IGENITY, Pfizer Animal Genetics, and a collaboration between researchers from Iowa State University and the University of Missouri-Columbia (ISU/UMC). The U.S. Meat Animal Research Center (USMARC; Clay Center, NE) has also developed MBV for 16 cattle breeds using 2 multibreed populations, the Germplasm Evaluation (GPE) Program and the 2,000 Bull Project (2K(ALL)), and 2 single breed subpopulations of the 2,000 Bull Project, Angus (2K(AN)) and Hereford (2K(HH)). In this study, these MBV were assessed relative to commercial ranch EBV estimated from the progeny phenotypes of Angus bulls naturally mated in multisire breeding pastures to commercial cows: 121 for USMARC MBV, 99 for ISU/UMC MBV, and 29 for IGENITY and Pfizer MBV (selected based on number of progeny carcass records). Five traits were analyzed: weaning weight (WW), HCW, marbling score (MS), rib-eye muscle area (RE), and, for IGENITY and Pfizer only, feedlot ADG. The average accuracies of MBV across traits were 0.38 ± 0.05 for IGENITY, 0.61 ± 0.12 for Pfizer, 0.46 ± 0.12 for ISU/UMC, 0.16 ± 0.04 for GPE, 0.26 ± 0.05 for 2K(ALL), 0.24 ± 0.04 for 2K(AN), and 0.02 ± 0.12 for 2K(HH). Angus-based MBV (IGENITY, Pfizer, ISU/UMC, and 2K(AN)) explained larger proportions of genetic variance in this population than GPE, 2K(ALL), or 2K(HH) MBV for the same traits. In this data set, IGENITY, Pfizer, and ISU/UMC MBV were predictive of realized performance of progeny, and incorporation of that information into national genetic evaluations would be expected to improve EPD accuracy, particularly for young animals.

  8. Issues Related to Recruitment of Enlisted Personnel for the Reserve Components. Volume 3. Methods Volume. Wave III.

    DTIC Science & Technology

    1981-03-01

    OO3 b’ As.nciates for Rusearch in Behavior, 1971 -- 1978. O -3- TABLE 1-1. PRIOR SERVICE SUBSAINPLE SIZES PRIOF SERVICE AMEFS =NAMES# SUBSAYPLE...BLK.266 ST.36 SRVC, kALL DATE TIME INTERV RESULT GCNZALEZNELSOh ANINIC, I- r 111-17 167 ST 2 JAMAICA NV 11433 2 / __ 0 3 4 NA BY CB c B -I

  9. Chance Constrained Programming Methods in Probabilistic Programming.

    DTIC Science & Technology

    1982-03-01

    Financial and Quantitative Analysis 2, 1967. Also reproduced in R. F. Byrne et. al., eds.5tudies in Budgeting (Amsterdam: North Holland, 1971 ). [3...Rules for the E-Model of Chance-Constrained Programming," Management Science, 17, 1971 . [23] Garstka, S. J. "The Economic Equivalence of Several...Iowa City: The University of Iowa College of Business Administration, 1981). -3- (29] Kall , P. and A. Prekopa, eds, Recent Results in Stochastic

  10. Wartime Requirements for Ammunition Materiel and Personnel (WARRAMP). Volume II. Materiel Postprocessor Program Maintenance Manual

    DTIC Science & Technology

    1981-08-01

    00 .1 00 -0 71: 3.1%2 7.460 . 30 1.0 0 .950 AS .1491 .? 0o -T 00 .8 72: G3: 70; ARTY KALLS FATORS B0 050BR CAS T ERO 7?211 .000 1.70 .000 I.000 .1500...Administrative and Logistic Support (FASTALS), Documentation, Research Analysis Corporation, RAC-R-86, dated May 1971 . F. Army Automation, Documentation Standards

  11. Remotely Piloted Vehicles Design Option Decision Trees

    DTIC Science & Technology

    1975-06-01

    of Lrade-off options available before inception of hardware design (Askren and Korkan, 1971 ; Askren, Korkan, and Watts, 1973). The purpose of the study...bouso~ENGIN LAVEIVESi SLIPSTRCA LAS? SOURCE HIGH LIFT DEVICE$ FLAPS SIGESO GRACES~~~ -AULILESOrCTER kALL T RCD TEMPERATUR EQUIPNENT COS,.UV...Method for Relating Human Resources Data to Design Parameters, AFHRL-TR-71-52, December 1971 . Barnes, B.P., Baker, L.A., and McIntosh, B.E., The

  12. Propagation of Sound Through the Atmosphere: Effects of Ground Cover

    DTIC Science & Technology

    1978-06-19

    Over Simulated Ground Cover", J. Acoust. Soc. Am. 49, 1069-1075 ( 1971 ). 8 J. . . Piercy, T. F. W. Embleton, and L. C. Sutherland, "A Review of Noise...FlPST., AM KALL C AND SUBMOUTINL NAIAE *𔃺’t.ATfl"v hISTTAD 0t "COPPIS?". C PANG4N IS Ali tUIT 01* IAANG4Kp [XCLUSVIfo UT NTt.14VENINC, Fj)ITSq C RANG

  13. High Mobility Driver Performance Analysis

    DTIC Science & Technology

    1981-06-01

    Adjusted Residuals 25 Table 13. Trials kAll Trials Including Civilian Drivers) During which Critical Incidents Occurred (Or Did Not Occur) 26 Table 14...0.05 (Winer, 1971 )3. At, the close of training an error score had been selected from amons alternative formulations as reasonably representative of...USNPA, Aug 1968. Winer, B. J. Statistical Principles in Experimental Design. Second (2d) edition. McGraw-Hill, New York, 1971 . 35 IN hi a. I i d A-14

  14. JPRS Report West Europe

    DTIC Science & Technology

    1988-08-12

    that first graders are the nicest, like all in one big family. Well-behaved and obedient. Maybe Matti teases Maija a little bit and Pekka pushes Kalle ...France as early as 1971 . The system designed for Finland is an all-weather ver- sion and it was originally intended to specifically destroy low-flying...ISTAT study covers principally the three years of 1984-86, but also examines the evolution of crime in Italy since 1971 . And this could not have

  15. Archaeological Investigations at Site 45-OK-11, Chief Joseph Dam Project, Washington.

    DTIC Science & Technology

    1984-01-01

    Russian thistle (_Iol]L kALL ), and thistle ( r_ _ium spp.) among others. Scattered sagebrush and rabbitbrush . (Chrysothamnus nauseosus), and a dense...described in detail selectively. All artifact analyses take the form of paradigmatic classifications as defined by Dunnell ( 1971 , 1979). In this system...with certain methods of production and particular steps in the reductive sequence (e.g., Crabtree 1972, 1976a,b; Flenniken and Garrison 1975; Muto 1971

  16. Selectivity of Odorant Receptors in Insects

    DTIC Science & Technology

    2012-07-13

    Regnier, 1971 ), which is equivalent to an endogenous agonist, may be expanded to include the following criteria: 1. Semiochemicals are natural...journal.pone.0030304 Law, J. H., and Regnier, F. E. ( 1971 ). Pheromones. Annu. Rev. Biochem. 40, 533–548. Lu, T., Qiu, Y. T., Wang, G., Kwon, J. Y...malaria vector mosquito Anopheles gambiae. Curr. Biol. 17, 1533–1544. Lundin, C., Kall , L., Kreher, S. A., Kapp, K., Sonnhammer, E. L., Carlson, J. R

  17. Man-Machine Interface (MMI) Requirements Definition and Design Guidelines

    DTIC Science & Technology

    1981-02-01

    be provided to interrogate the user to resolve any input ambiguities resulting from hardware limitations; see Smith and Goodwin, 1971 . Reference...Smith, S. L. and Goodwin, N. C’. Alphabetic data v entry via the Touch-Tone pad: A comment. Human Factors, 1971 , 13(2), 189-190. 41 All~ 1.0 General (con...software designer. Reference: Miller, R. B. Response time in man-computer conversational transactions. In Proceedings of the AFIPS kall Joint Computer

  18. Cardiorespiratory Changes During Microwave-Induced Lethal Heat Stress and Beta-adrenergic Blockade

    DTIC Science & Technology

    1994-01-01

    J. A. Taylor, J. K . Kalls , J. Nit- verse these responses. Fundam. Appl. Toxicol. 10- 506-516, 1988. tolo, R. W. Hicks, T. G. Lohmnan, and J. H...propanolol groups were significantly lower than in saline controls. Respiratory rate was significantly elevated during most of the exposure period in...lar and respiratory changes) during lethal exposures. Al- propranolol groups were significantly lower than in saline con- though the pathophysiology

  19. Development and Evaluation of a Casualty Evacuation Model for a European Conflict.

    DTIC Science & Technology

    1987-08-18

    W Applications and Computations," lIE Transactions, 16, 2, 127-134 "- ( 1984 ).-,’’ ,., 3. Ali, A. I., Helgason, R. V., Kennington, J. L., and kall ...Part II," Mathematical Programming, 1, 6-25 ( 1971 ). 38. Held, M., Wolfe, P., and Crowder, H., "Validation of Subgradient Optimization", Mathematical...California, Los Angeles, CA, ( 1971 ). Si 66. Swoveland, C., "A Two-Stage Decomposition Algorithm for a Generalized Muticommodity Flow Problem," INFOR

  20. When the Japanese Bombed the Huertgen Forest: How the Army’s Investigation of Pearl Harbor Influenced the Outcome of the Huertgen Forest, Major General Leonard T. Gerow and His Command of V Corps from 1943-1945

    DTIC Science & Technology

    2011-05-19

    only a narrow supply line that passed along a narrow one-lane path called the Kall Trail.13 The Germans mounted fierce counter-attacks well supported...Bradley. New York: Ballantine Books, 1971 . ________. West Wall: The Battle For Hitler’s Siegfried Line. Conshohocken, PA.: Da Capo Press, 2000

  1. The Combined Arm Battalion and Airland Battle,

    DTIC Science & Technology

    1986-12-01

    through Vossenach, across the Kall River, and on to Kommerscheidt and Schmidt. Although this trail was the major route for reinforcements and resupply...the division. The use of armor in support of the operation wa3 al-ii oo. Tanks were unable to traverse the narro)w and steeply ba:iked K .-il River...from the 53rd Armored Infantry Battalion opened up the bridgehead over the Moselle River in the initial movement towards ChateaU- 48 Salins . In this

  2. Revegetation Study of Adobe Dam, Phoenix, Arizona. Task 2. Revision.

    DTIC Science & Technology

    1983-08-01

    revegetation. *~ ~ A DDoa or?, I47 MDTOOOV 65IS OBSOLETE SECURITY CLASSIFICATION OF THIS PAGE (Wh"e Ders, Enreedl k ’, ... . .- r77. -. r - -V...addition to sodic soils, five sites along the wash were discovered to have salinity problems, with electrical conductivity in excess of 4. mmhos/cm. This...established at Indian Bend Wash.This species, along with Salla kalL (Tumbleweed) made upthe majority of the vegetation in 1979. Since 1979, as thedata in

  3. Seamless Integration of Detection and Therapy for Breast Cancer using Targeted Engineered Nanoparticles

    DTIC Science & Technology

    2006-06-01

    Rangel, R.; Sun, Y.; Zaoui, K.; Schmidt, M.; Kalle, C. v.; Weitzman, M. D.; Gelovani, J. G.; Pasqualini , R.; Arap, W., A Hybrid Vector for Ligand...A.; Holbeck, S. L.; Sausville, E. A.; Arap, 7 W.; Pasqualini , R., Ligand-Directed Surface Profiling of Human Cancer Cells with Combinatorial...Ozawa, M. G.; Snyder, E. Y.; Sidman, R. L.; Miller, J. H.; Arap, W.; Pasqualini , R., Networks of gold nanoparticles and bacteriophage as biological

  4. A Synopsis of the Chemical/Physical Properties of Seawater

    DTIC Science & Technology

    1988-01-01

    N20 -59.5965 97.3066 24.1406 -0.058420 0.033193 -0.0051313 4 1Weiss (1970), 2Weiss ( 1971 ), 3 Wiesenburg and Guinasso (1979), 4 Weiss and Price...20 30 40 50 60 70 80 90100 Temperature ( ° C) FIG. 5. Velocity of light in pure water and seawater as a function of temperature, from Kalle (1942...of Sheet Pile Structures, from U.S. Navy Design Manual ( 1971 ). Types of structure Factors affecting deterioration Harbor bulkheads Beach bulkheads

  5. Vector/Matrix Quantization for Narrow-Bandwidth Digital Speech Compression.

    DTIC Science & Technology

    1982-09-01

    8217o 0 -X -u -vc "oi ’" o 0 00i MN nM I -r -: I I Ir , I C 64 ut c 4c -C ;6 19I *~I C’ I I I 1 Kall 9 I I V4 S.0 M r4) ** al Iw* 0 0 10* 0 f 65 signal...Prediction of the Speech Wave, JASA Vol. 50, pp. 637-655, April 1971 . - 2. I. Itakura and S. Saito, Analysis Synthesis Telephony Based Upon the Maximum

  6. Wavevector-Frequency Analysis with Applications to Acoustics

    DTIC Science & Technology

    1994-01-01

    Turbulent Boundary Layer Pressure Measured by Microphone Arrays," Journal of the Acoustical Society of America, vol. 49, no. 3, March 1971 , pp. 862-877. 1...ARplications of Green’s FuntionsinScie,.-and Enginlering, Prentice-Hall, Inc., Englewood Hills, NJ, 1971 . 9. 3. Ffowcs-Williams et al., Modern Methods for...variables of a random process are kalled Joint w.merit ,. The m,n-th joint moment of the random variables, v and w, iz flefined by E ,N 1 f (aB) do d- where

  7. Survivability Study of a FLIR Equipped Fighter on a Night Penetration of a Soviet Army.

    DTIC Science & Technology

    1981-03-01

    4L TATL KALL . .5500E.1 .:02SE+I .55015E+00 .I 1E+II .II#E+#Z it 102 ’I" ADnend i x ( RANG;ES Comni r er 1’rn rqm Thft; nrnpram rnmniitpq the r ximum...VEL SIGMA .584 1 .514 .097 .756 1971 = ALT SIGMA 142.675 2 71.337 13.724 ,W91 1080= 1690= 3-WAY INTERACTIONS 52.133 16 3.258 .627 .868 1I#= NET RATE VEL

  8. Solution Methods for Stochastic Dynamic Linear Programs.

    DTIC Science & Technology

    1980-12-01

    16, No. 11, pp. 652-675, July 1970. [28] Glassey, C.R., "Dynamic linear programs for production scheduling", OR 19, pp. 45-56. 1971 . 129 Glassey, C.R...Huang, C.C., I. Vertinsky, W.T. Ziemba, ’Sharp bounds on the value of perfect information", OR 25, pp. 128-139, 1977. [37 Kall , P., ’Computational... 1971 . [701 Ziemba, W.T., *Computational algorithms for convex stochastic programs with simple recourse", OR 8, pp. 414-431, 1970. 131 UNCLASSI FIED

  9. Radio Wave Propagation: A Handbook of Practical Techniques for Computing Basic Transmission Loss and Field Strength

    DTIC Science & Technology

    1982-09-01

    MARK A. WEISSBEGU KALLE R. XONTSON Project Msnaqer, IUTRZ Assistant Director Contractor Operations Approved by CRARLES L. FLYNN, 001, us A. M. MESSE...34 BSTJ, 1946. 2-4priis, H.T., "Introduction to Radio and Antennas," IEEE Spectrum, April, 1971 . RADIO WAVE PROPAGATION: A HANDBOOK OF PRACTICAL...Propagation Tests, TR-0177-71.01, Gautney & Jones Communications, Inc., Falls Church, VA, June 1971 . 3 -7 Comparison of Predicted VLF/LF Signal

  10. A Dermatologist's Ammunition in the War Against Smoking: A Photoaging App.

    PubMed

    Brinker, Titus Josef; Enk, Alexander; Gatzka, Martina; Nakamura, Yasuhiro; Sondermann, Wiebke; Omlor, Albert Joachim; Petri, Maximilian Philip; Karoglan, Ante; Seeger, Werner; Klode, Joachim; von Kalle, Christof; Schadendorf, Dirk

    2017-09-21

    This viewpoint reviews the perspectives for dermatology as a specialty to go beyond the substantial impact of smoking on skin disease and leverage the impact of skin changes on a person's self-concept and behavior in the design of effective interventions for smoking prevention and cessation. ©Titus Josef Brinker, Alexander Enk, Martina Gatzka, Yasuhiro Nakamura, Wiebke Sondermann, Albert Joachim Omlor, Maximilian Philip Petri, Ante Karoglan, Werner Seeger, Joachim Klode, Christof von Kalle, Dirk Schadendorf. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 21.09.2017.

  11. Regenerative Simulation of Response Times in Networks of Queues.

    DTIC Science & Technology

    1979-11-01

    i jobs at center 1. Nov consider the network of queues in Figure 2.2, formulated (Lewis and Shedler ( 1971 )) as a model of system overhead in...7.2 leading to point estimates and confidence intervals for the quantity r(f) are that the pairs of random variables {( V(fHk) : kall (9.2.3) are...189 Next we show that P’=P. Since P ’m"CIP for all i, we can use the Skorohod representation theorem (see Skorohod (1956) or Billingsley ( 1971 )) to

  12. Uranium Oxide Gaseous Ion and Neutral Infrared Spectroscopy

    DTIC Science & Technology

    1983-12-31

    Kallelis , and q technical advice received from Drs. Charles E. Kolb, Kurt Annen, Alan Stanton, * and Mark Zahniser of Aerodyne and G. Sargent Janes of Avco...Chem. 75, ( 1971 ) 2283. - S6. S. Abramowitz and N. Acquista, J. Phys. Chem. 76, (1972) 647. 7. H.J. Leary, Jr., T.A. Rooney, E.D. Cater, and ll.B...Friedrich, High Temp. Scd. 3, ( 1971 ) 433. 8. D.H.W. Carstens, D.M. Gruen, and J.F. Kozlowski, High Temp. Sed. 4, 436 (1972). 9. a) M.J. Krauss and W.J

  13. NPS-PASCAL. A Microcomputer-based Implementation of the PASCAL Programming Language.

    DTIC Science & Technology

    1980-03-01

    rCL (N BASED PRINTNAME)(1) BTEV; CALL LI ’ ITS (I: =N (0)4-7); CALL 7NTEmRtLINKS; 12%- CALL ST A DrRT ( ); PY’EPTR(e)= FOR" kALL S7ET.DDRPTR(!K...kAccI, 1971 . 7* Flynn.,C P. and Moranville, .S., kL-;T_-v0 T -Dl1e7-itaticn Cf A Fi-I 1-vel 3o tt~ lanr’uape F-cr A M’icroccssor-bs- C~’-:uter Sy st

  14. Pleiotrophin as a Growth Factor and Therapeutic Target in Breast Cancer

    DTIC Science & Technology

    1997-10-01

    novel phospholipase A2 related gene. Nucl Acid Res 21:135-143. 11. Gattoni-Celli, S., K . Kirsch, S. Kalled , and K . J. Isselbacher. 1986. Expression...clone (G11-F7) is enlarged. Genomic Southern blot probes (a,b,c) and restriction sites are shown (B=BamHI, H=HindIII, Sc=ScaI, K =KpnI). 10WJ 3fr 4&V...otherwise in 25 mM Tris pH8.3/200 mM glycine/20% methanol. The membrane was blocked in PBS (phospate-buffered saline )/0.1% Tween 20/5% powdered milk and

  15. Oxidation of Thiodiglycol (2,2’-Thiobis-ethanol) by Alcohol Dehydrogenase: Comparison of Human Isoenzymes

    DTIC Science & Technology

    2000-01-01

    Ethanol by ADH Isozymes0 Isozyme TDC Ethanol Class K „ b *cat/-Nn K , *cat Kall ^m I act 8.6 (7.9 ± 1.2)e 63 7 4.2 54 13 PiPi 3.5 (4.2 ± 0.4) 34 8 0.05...the appropriate concentration of substrate in 0.85% saline was added. The reaction was followed by measuring the change in absorbance at 340 nm...ß2ß2 from Kedishvili et al. [271. * K „ values obtained from Lineweaver-Burk plots (Figure 1). ’Values in parentheses are X„s ± S.E. calculated from

  16. Numerical Methods for Synoptic Computation of Oceanic Fronts and Water Type Boundaries and their Significance in Applied Oceanography

    DTIC Science & Technology

    1966-06-01

    and L. C. Clarke 1965 Clarke, L. C. and R. J. Renard 1966 Dietrich, G. and K . Kalle 1957 Dietrich, G. 1964 Griffiths, R. C. 1965 Hela...8217s n AppA. 1 (sd LiceanGgrapny« (9) T s c h n 1 ’■■- a i. n Q ’z.e , ■: 10) Ci Bf k e , I..... ^ i-’ •■ (10) i...aevastu , i . ill) J u...only between water masses of different salinity but also between those differing in other properties, such as temperature." The nature of the oceanic

  17. Impact of 1/8 degree to 1/64 degree Resolution on Gulf Stream Model-Data Comparisons in Basin-Scale Subtropical Atlantic Ocean Models

    DTIC Science & Technology

    2000-01-01

    Momentum Fluxes. NOAA Atlas NESDIS 8 vol. 3 US Department of Commerce, NOAA, NESDIS, 413 p. Dietrich, G., Kalle , K ., Krauss, K ., Siedler, G., 1980...depth, hydrodynamic model are given below for layers ks1 . . . n with ks1 for the top layer. In places where k is used to index model interfaces, ks0 is...the surface and ksn is the bottom. EU 1 E U u E V u cosuŽ . Ž . k k k k k q q yV u sinuqaV sin2uŽ . k k Et acosu Ef Eu sqmax 0,yv u qmax 0,v u y max 0

  18. Davis Monthan AFB Tucson, Arizona. Revised Uniform Summary of Surface Weather Observations (RUSSWO)

    DTIC Science & Technology

    1976-07-01

    ATA PRUCCSSING BRANC𔃾 UAF ElA CEILING VERSUS VISIBILITY +-AIR W/ kAll ’ , SIRVICEI/1iC 2JIU9 D, V1S MU 1IMA, AFB AkIZONAUC51UCI) ,)-45peif8-75 DEC 5T+O... 1971 蔵 69j "l 1 .74 681 0 2 2 626 103 -42/;Ol3j 14 - 1120 L -,AN 4--- - -- - 27, 313 ____ ____- --- K -- --±-183 ni n 166 42 mn Wkl I _ 1 1...161 1971 187 5 1 541 53 1 1 .2 . .4 .1 .7 l.3 .4 .7 #. 1 1__6 L 1_0 11 2 58/ 47,*00 0 0 94 *l .2 iol2 5-- 49 .Q .49 . .7 .6 .7 .5 o0 10_

  19. Summary of Meteorological Observations, Surface (SMOS), Midway Island.

    DTIC Science & Technology

    1984-08-01

    8 1.7 415 !I _? .,8 1.3.. 35 1962 9 ’.2 32 l󈧽 9 t.o 27 1965 10 1.2 2 1062 10 1 z1 1*6?2 11 1 - 641 ’ .E 24 1971 12 ’.11 1 !97 12 100 77 19 __9 13 1... 1971 22 1. 4 72 19ev 22 2 0 < 53 1’$6 7_______ 23 *1 . 961 23 1.13 2 ; 1981 24 ". 1’ 5 46P 24 1.-4 42’ 1952 25 ’. 0 36 1i)79 26 l.’b %s 蚝 1 26 𔃻. 6...OBSERVATIONS) j2 7ŕ 74!:WAY !SLA.𔃼 73-R2 MAY SiUUlm iS&AYWI MUl Y IOUAI kALL WEATHEP IP MMW=N ( L.8.1 . SIf, UL S aiim MEAN INTS I13 4.6 7-10 1114 17.21

  20. Patient-Centered Mobile Health Data Management Solution for the German Health Care System (The DataBox Project).

    PubMed

    Brinker, Titus Josef; Rudolph, Stefanie; Richter, Daniela; von Kalle, Christof

    2018-05-11

    This article describes the DataBox project which offers a perspective of a new health data management solution in Germany. DataBox was initially conceptualized as a repository of individual lung cancer patient data (structured and unstructured). The patient is the owner of the data and is able to share his or her data with different stakeholders. Data is transferred, displayed, and stored online, but not archived. In the long run, the project aims at replacing the conventional method of paper- and storage-device-based handling of data for all patients in Germany, leading to better organization and availability of data which reduces duplicate diagnostic procedures, treatment errors, and enables the training as well as usage of artificial intelligence algorithms on large datasets. ©Titus Josef Brinker, Stefanie Rudolph, Daniela Richter, Christof von Kalle. Originally published in JMIR Cancer (http://cancer.jmir.org), 11.05.2018.

  1. The costs and benefits of a cigarette ban.

    PubMed

    Doucet, Mathieu

    2017-06-01

    The death toll from tobacco is staggering: it might contribute to one billion premature deaths over the course of the 21st century. In 'The case for banning cigarettes', Kalle Grill and Kristin Voigt argue that the well-being and equality benefits of a complete ban on cigarettes more than justify the restrictions on autonomy that such a ban would impose. Their argument depends on two crucial simplifications: an assumption that the ban would be effective and the restriction of the analysis to a comparison with the status quo, rather than a broader range of policy options. I argue that despite the authors' claims, these two simplifications make it impossible for their argument to 'bring into focus the fundamental normative issues' surrounding a possible cigarette ban, since they dramatically overstate the benefits and obscure the most significant costs of such a ban. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  2. Hoechst and Wacker plan joint venture in PVC

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Young, I.

    1992-12-02

    Restructuring of Europe's petrochemical industry has taken a further step with the announcement that Hoechst (Frankfurt) and Wacker Chemie (Munich) are planning a joint venture in polyvinyl chloride (PVC). The venture would include production, R D, sales and marketing, plus both companies' PVC recycling activities. However, their vinyl chloride monomer (VCM) plants, and Hoechst's Kalle PVC film business, have been left out. Erich Schnitzler, head of Hoechst's PVC business unit, does not anticipate problems with the European Community's competition directorate. We are both among the middle-sized European PVC producers, and together we would have a 9%-10% market share. Our jointmore » venture would not limit competition. Both partners are hoping for approval from Brussels in first-quarter 1993. Hoechst has 255,000 m.t./year of PVC capacity at Gendorfand Knapsack, while Wacker has 365,000 m.t./year at Burghausen and Cologne. All the units, except Wacker's Cologne plant, are back integrated to VCM. The joint venture would buy VCM from the two parent companies and on the merchant market.« less

  3. Inferring patterns of folktale diffusion using genomic data

    PubMed Central

    Bortolini, Eugenio; Pagani, Luca; Sarno, Stefania; Boattini, Alessio; Sazzini, Marco; da Silva, Sara Graça; Martini, Gessica; Metspalu, Mait; Pettener, Davide; Luiselli, Donata; Tehrani, Jamshid J.

    2017-01-01

    Observable patterns of cultural variation are consistently intertwined with demic movements, cultural diffusion, and adaptation to different ecological contexts [Cavalli-Sforza and Feldman (1981) Cultural Transmission and Evolution: A Quantitative Approach; Boyd and Richerson (1985) Culture and the Evolutionary Process]. The quantitative study of gene–culture coevolution has focused in particular on the mechanisms responsible for change in frequency and attributes of cultural traits, the spread of cultural information through demic and cultural diffusion, and detecting relationships between genetic and cultural lineages. Here, we make use of worldwide whole-genome sequences [Pagani et al. (2016) Nature 538:238–242] to assess the impact of processes involving population movement and replacement on cultural diversity, focusing on the variability observed in folktale traditions (n = 596) [Uther (2004) The Types of International Folktales: A Classification and Bibliography. Based on the System of Antti Aarne and Stith Thompson] in Eurasia. We find that a model of cultural diffusion predicted by isolation-by-distance alone is not sufficient to explain the observed patterns, especially at small spatial scales (up to ∼4,000 km). We also provide an empirical approach to infer presence and impact of ethnolinguistic barriers preventing the unbiased transmission of both genetic and cultural information. After correcting for the effect of ethnolinguistic boundaries, we show that, of the alternative models that we propose, the one entailing cultural diffusion biased by linguistic differences is the most plausible. Additionally, we identify 15 tales that are more likely to be predominantly transmitted through population movement and replacement and locate putative focal areas for a set of tales that are spread worldwide. PMID:28784786

  4. Inferring patterns of folktale diffusion using genomic data.

    PubMed

    Bortolini, Eugenio; Pagani, Luca; Crema, Enrico R; Sarno, Stefania; Barbieri, Chiara; Boattini, Alessio; Sazzini, Marco; da Silva, Sara Graça; Martini, Gessica; Metspalu, Mait; Pettener, Davide; Luiselli, Donata; Tehrani, Jamshid J

    2017-08-22

    Observable patterns of cultural variation are consistently intertwined with demic movements, cultural diffusion, and adaptation to different ecological contexts [Cavalli-Sforza and Feldman (1981) Cultural Transmission and Evolution: A Quantitative Approach ; Boyd and Richerson (1985) Culture and the Evolutionary Process ]. The quantitative study of gene-culture coevolution has focused in particular on the mechanisms responsible for change in frequency and attributes of cultural traits, the spread of cultural information through demic and cultural diffusion, and detecting relationships between genetic and cultural lineages. Here, we make use of worldwide whole-genome sequences [Pagani et al. (2016) Nature 538:238-242] to assess the impact of processes involving population movement and replacement on cultural diversity, focusing on the variability observed in folktale traditions ( n  = 596) [Uther (2004) The Types of International Folktales: A Classification and Bibliography. Based on the System of Antti Aarne and Stith Thompson ] in Eurasia. We find that a model of cultural diffusion predicted by isolation-by-distance alone is not sufficient to explain the observed patterns, especially at small spatial scales (up to [Formula: see text]4,000 km). We also provide an empirical approach to infer presence and impact of ethnolinguistic barriers preventing the unbiased transmission of both genetic and cultural information. After correcting for the effect of ethnolinguistic boundaries, we show that, of the alternative models that we propose, the one entailing cultural diffusion biased by linguistic differences is the most plausible. Additionally, we identify 15 tales that are more likely to be predominantly transmitted through population movement and replacement and locate putative focal areas for a set of tales that are spread worldwide.

  5. Uncertainty estimation of predictions of peptides' chromatographic retention times in shotgun proteomics.

    PubMed

    Maboudi Afkham, Heydar; Qiu, Xuanbin; The, Matthew; Käll, Lukas

    2017-02-15

    Liquid chromatography is frequently used as a means to reduce the complexity of peptide-mixtures in shotgun proteomics. For such systems, the time when a peptide is released from a chromatography column and registered in the mass spectrometer is referred to as the peptide's retention time . Using heuristics or machine learning techniques, previous studies have demonstrated that it is possible to predict the retention time of a peptide from its amino acid sequence. In this paper, we are applying Gaussian Process Regression to the feature representation of a previously described predictor E lude . Using this framework, we demonstrate that it is possible to estimate the uncertainty of the prediction made by the model. Here we show how this uncertainty relates to the actual error of the prediction. In our experiments, we observe a strong correlation between the estimated uncertainty provided by Gaussian Process Regression and the actual prediction error. This relation provides us with new means for assessment of the predictions. We demonstrate how a subset of the peptides can be selected with lower prediction error compared to the whole set. We also demonstrate how such predicted standard deviations can be used for designing adaptive windowing strategies. lukas.kall@scilifelab.se. Our software and the data used in our experiments is publicly available and can be downloaded from https://github.com/statisticalbiotechnology/GPTime . © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

  6. Complex Systems: Control and Modeling Problems

    DTIC Science & Technology

    2004-08-23

    von Mat- thias Kalle Dalheimer. - 4. Aufl.. - Beijing ; Koln : O’Reilly, 2003. - XVII, 1084 S.; (dt.) ISBN 3-89721- 332-X Original: Java in a...Берлин: Техник, 1988. [7] Форрестер Д. Основы кибернетики предприятия (индустриальная динамика): Пер. с англ. – М.: Про- гресс, 1971 . 385...размерности системы уравнений для синтеза оптимального управления. Оптимальные и самонастраивающиеся системы. – Новосибирск: Изд. ИАиЭ АН СССР, 1971

  7. Chemistry of the Marlboro Clay in Virginia and Implications for the Paleocene-Eocene Thermal Maximum

    NASA Astrophysics Data System (ADS)

    Zimmer, M.; Cai, Y.; Corley, A.; Liang, J. A.; Powars, D.; Goldstein, S. L.; Kent, D. V.; Broecker, W. S.

    2017-12-01

    The Paleocene-Eocene Thermal Maximum (PETM) was a global hyperthermal ( 5ºC warming) event marked by a rapid carbon isotope excursion (CIE) of >1‰ in the marine carbonate record (e.g. Zeebe et al. Nature Geoscience 2009). Possible explanations for the CIE include intrusion of a sill complex into organic carbonate (Aarnes et al. J. Geol. Soc. 2015), dissolution of methane hydrates (Thomas et al. Geology 2002), and a comet impact event (Schaller et al. Science 2016). Here we present new data across the PETM from the VirginiaDEQ-USGS Surprise Hill (SH) core, Northumberland Co., VA. We analyzed the Marlboro Clay, a thick, kaolinite-rich clay unit that marks the initiation of the PETM in the mid-Atlantic Coastal Plain of North America, as well as units above and below it. Bulk sediment records a δ13C excursion of approximately -5‰ across the CIE, while benthic foraminifera (Cibicidoides spp.) record a synchronous excursion of approximately -4.5‰. These results are consistent with other records from the New Jersey Coastal Plain (Makarova et al. Paleoceanography 2017). The excursion coincides with an increase in magnetic susceptibility, a decrease in bulk CaCO3 content, and an 2.5‰ decrease of δ18O in both the bulk sediment and benthic foraminifera of the SH core. Pb isotope analyses of the <63 μm fraction sediments indicate a unique provenance make-up for the Marlboro Clay. The results of the study thus indicate that PETM Marlboro Clay was not generated simply by intensified weathering of the same source area as the underlying Aquia Formation and overlying Nanjemoy Formation. Any hypothesis that aims to explain the mechanism that triggered the PETM must also account for the observed distinct provenance make-up of the Marlboro Clay.

  8. Spectrofluorimetric determination of melatonin in kernels of four different Pistacia varieties after ultrasound-assisted solid-liquid extraction.

    PubMed

    Oladi, Elham; Mohamadi, Maryam; Shamspur, Tayebeh; Mostafavi, Ali

    2014-11-11

    Melatonin is normally consumed to regulate the body's biological cycle. However it also has therapeutic properties, such as anti-tumor, anti-aging and protects the immune system. There are some reports on the presence of melatonin in edible kernels such as walnuts, but the extraction of melatonin from pistachio kernels is reported here for the first time. For this, the methanolic extract of pistachio kernels was exposed to gas chromatography/mass spectrometry analysis which confirmed the presence of melatonin. A fluorescence-based method was applied for the determination of melatonin in different extracts. When excited at λ=275 nm, the fluorescence emission intensity of melatonin was measured at λ=366 nm. Ultrasound-assisted solid-liquid extraction was used for the extraction of melatonin from pistachio kernels prior to fluorimetric determination. To achieve the highest extraction recovery, the main parameters affecting the extraction efficiency such as extracting solvent type and volume, temperature, sonication time and pH were evaluated. Under the optimized conditions, a linear dependence of fluorescence intensity on melatonin concentration was observed in the range of 0.0040-0.160 μg mL(-1), with a detection limit of 0.0036 μg mL(-1). This method was applied successfully for measuring and comparing the melatonin content in the kernels of four different varieties of Pistacia including Ahmad Aghaei, Akbari, Kalle Qouchi and Fandoghi. In addition, the results obtained were compared with those obtained using GC/MS. A good agreement was observed indicating the reliability of the proposed method. Copyright © 2014 Elsevier B.V. All rights reserved.

  9. Spectrofluorimetric determination of melatonin in kernels of four different Pistacia varieties after ultrasound-assisted solid-liquid extraction

    NASA Astrophysics Data System (ADS)

    Oladi, Elham; Mohamadi, Maryam; Shamspur, Tayebeh; Mostafavi, Ali

    2014-11-01

    Melatonin is normally consumed to regulate the body's biological cycle. However it also has therapeutic properties, such as anti-tumor, anti-aging and protects the immune system. There are some reports on the presence of melatonin in edible kernels such as walnuts, but the extraction of melatonin from pistachio kernels is reported here for the first time. For this, the methanolic extract of pistachio kernels was exposed to gas chromatography/mass spectrometry analysis which confirmed the presence of melatonin. A fluorescence-based method was applied for the determination of melatonin in different extracts. When excited at λ = 275 nm, the fluorescence emission intensity of melatonin was measured at λ = 366 nm. Ultrasound-assisted solid-liquid extraction was used for the extraction of melatonin from pistachio kernels prior to fluorimetric determination. To achieve the highest extraction recovery, the main parameters affecting the extraction efficiency such as extracting solvent type and volume, temperature, sonication time and pH were evaluated. Under the optimized conditions, a linear dependence of fluorescence intensity on melatonin concentration was observed in the range of 0.0040-0.160 μg mL-1, with a detection limit of 0.0036 μg mL-1. This method was applied successfully for measuring and comparing the melatonin content in the kernels of four different varieties of Pistacia including Ahmad Aghaei, Akbari, Kalle Qouchi and Fandoghi. In addition, the results obtained were compared with those obtained using GC/MS. A good agreement was observed indicating the reliability of the proposed method.

  10. Commentary on "integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer." Weischenfeldt J, Simon R, Feuerbach L, Schlangen K, Weichenhan D, Minner S, Wuttig D, Warnatz HJ, Stehr H, Rausch T, Jäger N, Gu L, Bogatyrova O, Stütz AM, Claus R, Eils J, Eils R, Gerhäuser C, Huang PH, Hutter B, Kabbe R, Lawerenz C, Radomski S, Bartholomae CC, Fälth M, Gade S, Schmidt M, Amschler N, Haß T, Galal R, Gjoni J, Kuner R, Baer C, Masser S, von Kalle C, Zichner T, Benes V, Raeder B, Mader M, Amstislavskiy V, Avci M, Lehrach H, Parkhomchuk D, Sultan M, Burkhardt L, Graefen M, Huland H, Kluth M, Krohn A, Sirma H, Stumm L, Steurer S, Grupp K, Sültmann H, Sauter G, Plass C, Brors B, Yaspo ML, Korbel JO, Schlomm T, Genome Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany.: Cancer Cell 2013;23(2):159-70.

    PubMed

    Olumi, Aria F

    2014-02-01

    Early-onset prostate cancer (EO-PCA) represents the earliest clinical manifestation of prostate cancer. To compare the genomic alteration landscapes of EO-PCA with "classical" (elderly-onset) PCA, we performed deep sequencing-based genomics analyses in 11 tumors diagnosed at young age, and pursued comparative assessments with seven elderly-onset PCA genomes. Remarkable age-related differences in structural rearrangement (SR) formation became evident, suggesting distinct disease pathomechanisms. Whereas EO-PCAs harbored a prevalence of balanced SRs, with a specific abundance of androgen-regulated ETS gene fusions including TMPRSS2:ERG, elderly-onset PCAs displayed primarily non-androgen-associated SRs. Data from a validation cohort of>10,000 patients showed age-dependent androgen receptor levels and a prevalence of SRs affecting androgen-regulated genes, further substantiating the activity of a characteristic "androgen-type" pathomechanism in EO-PCA. Copyright © 2014 Elsevier Inc. All rights reserved.

  11. A Genetic Basis for Functional Hypothalamic Amenorrhea

    PubMed Central

    Caronia, Lisa M.; Martin, Cecilia; Welt, Corrine K.; Sykiotis, Gerasimos P.; Quinton, Richard; Thambundit, Apisadaporn; Avbelj, Magdalena; Dhruvakumar, Sadhana; Plummer, Lacey; Hughes, Virginia A.; Seminara, Stephanie B.; Boepple, Paul A.; Sidis, Yisrael; Crowley, William F.; Martin, Kathryn A.; Hall, Janet E.; Pitteloud, Nelly

    2011-01-01

    BACKGROUND Functional hypothalamic amenorrhea is a reversible form of gonadotropin-releasing hormone (GnRH) deficiency commonly triggered by stressors such as excessive exercise, nutritional deficits, or psychological distress. Women vary in their susceptibility to inhibition of the reproductive axis by such stressors, but it is unknown whether this variability reflects a genetic predisposition to hypothalamic amenorrhea. We hypothesized that mutations in genes involved in idiopathic hypogonadotropic hypogonadism, a congenital form of GnRH deficiency, are associated with hypothalamic amenorrhea. METHODS We analyzed the coding sequence of genes associated with idiopathic hypogonadotropic hypogonadism in 55 women with hypothalamic amenorrhea and performed in vitro studies of the identified mutations. RESULTS Six heterozygous mutations were identified in 7 of the 55 patients with hypothalamic amenorrhea: two variants in the fibroblast growth factor receptor 1 gene FGFR1 (G260E and R756H), two in the prokineticin receptor 2 gene PROKR2 (R85H and L173R), one in the GnRH receptor gene GNRHR (R262Q), and one in the Kall-mann syndrome 1 sequence gene KAL1 (V371I). No mutations were found in a cohort of 422 controls with normal menstrual cycles. In vitro studies showed that FGFR1 G260E, FGFR1 R756H, and PROKR2 R85H are loss-of-function mutations, as has been previously shown for PROKR2 L173R and GNRHR R262Q. CONCLUSIONS Rare variants in genes associated with idiopathic hypogonadotropic hypogonadism are found in women with hypothalamic amenorrhea, suggesting that these mutations may contribute to the variable susceptibility of women to the functional changes in GnRH secretion that characterize hypothalamic amenorrhea. Our observations provide evidence for the role of rare variants in common multifactorial disease. (Funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development and others; ClinicalTrials.gov number, NCT00494169.) PMID:21247312

  12. Sensitivity of annual mass balance gradient and Hypsometry to the changing climate: the case of Dokriani Glacier, central Himalaya, India

    NASA Astrophysics Data System (ADS)

    Pratap, B.

    2015-12-01

    The glacier mass balance is undelayed, unfiltered and direct method to assess the impact of climate change on the glaciers. Many studies suggest that some of the Himalayan glaciers have lost their mass at an increased rate during the past few decades. Furthermore, the mass balance gradient and hypsometric analysis are important to understand the glacier response towards climatic perturbations. Our long term in-situ monitoring on the Dokriani Glacier provides great insights to understand the variability in central Himalayan glaciers. We report the relationship between glacier hypsometry and annual mass balance gradient (12 years) to understand the glacier's response towards climate change. Dokriani Glacier in the Bhagirathi basin is a small (7 km2) NNW exposed glacier in the western part of central Himalaya, India. The study analysed the annual balance, mass balance gradient and length changes observed during first decade of 21st century (2007-2013) and compare with the previous observations of 1990s (1992-2000). A large spatial variability in the mass balance gradients of two different periods has been observed. The equilibrium-line altitude (ELA) was fluctuated between 5000 and 5100 m a.s.l. and the derived time averaged ELA (ELAn) and balance budget ELA (ELA0) were 5075 and 4965 m a.s.l respectively during 1992-2013. The observed time-averaged accumulation-area ratio (AARn) and balance budget AAR (AAR0) were 0.67 and 0.72 respectively during 1992-2013. The higher value of AAR comprises due to flat and broader accumulation area (4.50 km2) of the glacier. Although, having larger accumulation area, the glacier has faced strong mass wasting with average annual ablation of -1.82 m w.e. a-1 in the ablation zone as compare to residual average annual accumulation of 0.41 m w.e. a-1. Based on the annual mass balance series (12 years) Dokriani Glacier has continuous negative annual balances with monotonically negative cumulative mass loss of -3.86 m w.e with the average loss of -0.32 m w.e a-1. Dokriani Glacier also showed continues recession from 1992 to present. Snout was ascended 95 m a.s.l. from an elevation of 3870 m a.s.l. in 1992 to an elevation of 3965 m a.s.l. in 2013. The progressive retreat of the glacier affects its extension and volume and covered by continuous enhancement of debris in the lower ablation zone.

  13. Evaluating potentials for future generation off-shore wind-power outside Norway

    NASA Astrophysics Data System (ADS)

    Benestad, R. E.; Haugen, J.; Haakenstad, H.

    2012-12-01

    With todays critical need of renewable energy sources, it is naturally to look towards wind power. With the long coast of Norway, there is a large potential for wind farms offshore Norway. Although there are more challenges with offshore wind energy installations compared to wind farms on land, the offshore wind is generally higher, and there is also higher persistence of wind speed values in the power generating classes. I planning offshore wind farms, there is a need of evaluation of the wind resources, the wind climatology and possible future changes. In this aspect, we use data from regional climate model runs performed in the European ENSEMBLE-project (van der Linden and J.F.B. Mitchell, 2009). In spite of increased reliability in RCMs in the recent years, the simulations still suffer from systematic model errors, therefore the data has to be corrected before using them in wind resource analyses. In correcting the wind speeds from the RCMs, we will use wind speeds from a Norwegian high resolution wind- and wave- archive, NORA10 (Reistad et al 2010), to do quantile mapping (Themeβl et. al. 2012). The quantile mapping is performed individually for each regional simulation driven by ERA40-reanalysis from the ENSEMBLE-project corrected against NORA10. The same calibration is then used to the belonging regional climate scenario. The calibration is done for each grid cell in the domain and for each day of the year centered in a +/-15 day window to make an empirical cumulative density function for each day of the year. The quantile mapping of the scenarios provide us with a new wind speed data set for the future, more correct compared to the raw ENSEMBLE scenarios. References: Reistad M., Ø. Breivik, H. Haakenstad, O. J. Aarnes, B. R. Furevik and J-R Bidlo, 2010, A high-resolution hindcast of wind and waves for The North Sea, The Norwegian Sea and The Barents Sea. J. Geophys. Res., 116. doi:10.1029/2010JC006402. Themessl M. J., A. Gobiet and A. Leuprecht, 2012, Empirical-statistical downscaling and error correction of regional climate models and its imipact on the climate change signal. Climatic Change 112: 449-468, DOI 10.1007/s10584-011-0224-4. Van der Linden P. and J.F.B. Mitchell, 2009, ENSEMBLES: Climate Change and its Impacts_ Summary and results from the ENSEMBLES project. Met Office Hadley Centre, FitzRoy Road, Exeter EX1 3PB, UK.

  14. Long-term coastal measurements for large-scale climate trends characterization

    NASA Astrophysics Data System (ADS)

    Pomaro, Angela; Cavaleri, Luigi; Lionello, Piero

    2017-04-01

    Multi-decadal time-series of observational wave data beginning in the late 1970's are relatively rare. The present study refers to the analysis of the 37-year long directional wave time-series recorded between 1979 and 2015 at the CNR-ISMAR (Institute of Marine Sciences of the Italian National Research Council) "Acqua Alta" oceanographic research tower, located in the Northern Adriatic Sea, 15 km offshore the Venice lagoon, on 16 m depth. The extent of the time series allows to exploit its content not only for modelling purposes or short-term statistical analyses, but also at the climatological scale thanks to the peculiar meteorological and oceanographic aspects of the coastal area where this relevant infrastructure has been installed. We explore the dataset both to characterize the local average climate and its variability, and to detect the possible long-term trends that might be suggestive of, or emphasize, large scale circulation patterns and trends. Measured data are essential for the assessment, and often for the calibration, of model data, generally, if long enough, also the reference also for climate studies. By applying this analysis to an area well characterized from the meteorological point of view, we first assess the changes in time based on measured data, and then we compare them to the ones derived from the ERA-Interim regional simulation over the same area, thus showing the strong improvement that is still needed to get reliable climate models projections on coastal areas and the Mediterranean Region as a whole. Moreover, long term hindcast aiming at climatic considerations are well known for 1) underestimating, if their resolution is not high enough, the actual wave heights as well as for 2) being strongly affected by different conditions over time that are likely to introduce spurious trends of variable magnitude. In particular the different amount, in time, of assimilated data by the hindcast models, directly and indirectly affects the results, making it difficult, if not impossible, to distinguish the imposed effects from the climate signal itself, as demonstrated by Aarnes et al. (2015). From this point of view the problem is that long-term measured datasets are relatively unique, due to the cost and technical difficulty of maintaining fixed instrumental equipment over time, as well as of assuring the homogeneity and availability of the entire dataset. For this reason we are furthermore working on the publication of the quality controlled dataset to make it widely available for open-access research purposes. The analysis and homogenization of the original dataset has actually required a substantial part of the time spent on the study, because of the strong impact that the quality of the data may have on the final result. We consider this particularly relevant, especially when referring to coastal areas, where the lack of reliable satellite data makes it difficult to improve the model capability to resolve the local peculiar oceanographic processes. We describe in detail any step and procedure used in producing the data, including full descriptions of the experimental design, data acquisition assays, and any computational processing needed to support the technical quality of the dataset.

  15. A Skin Cancer Prevention Facial-Aging Mobile App for Secondary Schools in Brazil: Appearance-Focused Interventional Study.

    PubMed

    Brinker, Titus Josef; Heckl, Marlene; Gatzka, Martina; Heppt, Markus V; Resende Rodrigues, Henrique; Schneider, Sven; Sondermann, Wiebke; de Almeida E Silva, Carolina; Kirchberger, Michael C; Klode, Joachim; Enk, Alexander H; Knispel, Sarah; von Kalle, Christof; Stoffels, Ingo; Schadendorf, Dirk; Nakamura, Yasuhiro; Esser, Stefan; Assis, Aisllan; Bernardes-Souza, Breno

    2018-03-09

    The incidence of melanoma is increasing faster than any other major cancer both in Brazil and worldwide. Southeast Brazil has especially high incidences of melanoma, and early detection is low. Exposure to ultraviolet (UV) radiation is a primary risk factor for developing melanoma. Increasing attractiveness is a major motivation among adolescents for tanning. A medical student-delivered intervention that takes advantage of the broad availability of mobile phones and adolescents' interest in their appearance indicated effectiveness in a recent study from Germany. However, the effect in a high-UV index country with a high melanoma prevalence and the capability of medical students to implement such an intervention remain unknown. In this pilot study, our objective was to investigate the preliminary success and implementability of a photoaging intervention to prevent skin cancer in Brazilian adolescents. We implemented a free photoaging mobile phone app (Sunface) in 15 secondary school classes in southeast Brazil. Medical students "mirrored" the pupils' altered 3-dimensional (3D) selfies reacting to touch on tablets via a projector in front of their whole grade accompanied by a brief discussion of means of UV protection. An anonymous questionnaire capturing sociodemographic data and risk factors for melanoma measured the perceptions of the intervention on 5-point Likert scales among 356 pupils of both sexes (13-19 years old; median age 16 years) in grades 8 to 12 of 2 secondary schools in Brazil. We measured more than 90% agreement in both items that measured motivation to reduce UV exposure and only 5.6% disagreement: 322 (90.5%) agreed or strongly agreed that their 3D selfie motivated them to avoid using a tanning bed, and 321 (90.2%) that it motivated them to improve their sun protection; 20 pupils (5.6%) disagreed with both items. The perceived effect on motivation was higher in female pupils in both tanning bed avoidance (n=198, 92.6% agreement in females vs n=123, 87.2% agreement in males) and increased use of sun protection (n=197, 92.1% agreement in females vs n=123, 87.2% agreement in males) and independent of age or skin type. All medical students involved filled in a process evaluation revealing that they all perceived the intervention as effective and unproblematic, and that all pupils tried the app in their presence. The photoaging intervention was effective in changing behavioral predictors for UV protection in Brazilian adolescents. The predictors measured indicated an even higher prospective effectiveness in southeast Brazil than in Germany (>90% agreement in Brazil vs >60% agreement in Germany to both items that measured motivation to reduce UV exposure) in accordance with the theory of planned behavior. Medical students are capable of complete implementation. A randomized controlled trial measuring prospective effects in Brazil is planned as a result of this study. ©Titus Josef Brinker, Marlene Heckl, Martina Gatzka, Markus V Heppt, Henrique Resende Rodrigues, Sven Schneider, Wiebke Sondermann, Carolina de Almeida e Silva, Michael C Kirchberger, Joachim Klode, Alexander H Enk, Sarah Knispel, Christof von Kalle, Ingo Stoffels, Dirk Schadendorf, Yasuhiro Nakamura, Stefan Esser, Aisllan Assis, Breno Bernardes-Souza. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 09.03.2018.

  16. EDITORIAL: Molecular switches at surfaces Molecular switches at surfaces

    NASA Astrophysics Data System (ADS)

    Weinelt, Martin; von Oppen, Felix

    2012-10-01

    In nature, molecules exploit interaction with their environment to realize complex functionalities on the nanometer length scale. Physical, chemical and/or biological specificity is frequently achieved by the switching of molecules between microscopically different states. Paradigmatic examples are the energy production in proton pumps of bacteria or the signal conversion in human vision, which rely on switching molecules between different configurations or conformations by external stimuli. The remarkable reproducibility and unparalleled fatigue resistance of these natural processes makes it highly desirable to emulate nature and develop artificial systems with molecular functionalities. A promising avenue towards this goal is to anchor the molecular switches at surfaces, offering new pathways to control their functional properties, to apply electrical contacts, or to integrate switches into larger systems. Anchoring at surfaces allows one to access the full range from individual molecular switches to self-assembled monolayers of well-defined geometry and to customize the coupling between molecules and substrate or between adsorbed molecules. Progress in this field requires both synthesis and preparation of appropriate molecular systems and control over suitable external stimuli, such as light, heat, or electrical currents. To optimize switching and generate function, it is essential to unravel the geometric structure, the electronic properties and the dynamic interactions of the molecular switches on surfaces. This special section, Molecular Switches at Surfaces, collects 17 contributions describing different aspects of this research field. They analyze elementary processes, both in single molecules and in ensembles of molecules, which involve molecular switching and concomitant changes of optical, electronic, or magnetic properties. Two topical reviews summarize the current status, including both challenges and achievements in the field of molecular switches on metal surfaces, focusing on electronic and vibrational spectroscopy in one case and scanning tunneling microscopy studies in the other. Original research articles describe results in many aspects of the field, including: Self-assembly, self-organization, and controlled growth of molecular layers on various substrates. Highly-ordered arrays provide model systems with extraordinary structural properties, allowing one to adjust interactions between molecules and between molecule and substrate, and can be robustly prepared from solution, an essential prerequisite for applications. Conformational or electronic switching of molecules adsorbed at metal and semiconductor surfaces. These studies highlight the elementary processes governing molecular switching at surfaces as well as the wide range of possible stimuli. Carbon-based substrates such as graphene or carbon nanotubes. These substrates are attractive due to their effective two-dimensionality which implies that switching of adsorbed molecules can effect a significant back-action on the substrate. Mechanisms of conformational switching. Several contributions study the role of electron-vibron coupling and heating in current-induced conformational switching. We hope that the collection of articles presented here will stimulate and encourage researchers in surface physics and interfacial chemistry to contribute to the still emerging field of molecular switches at surfaces. We wish to acknowledge the support and input from many colleagues in preparing this special section. A significant part of this work has been conducted in the framework of the Sonderforschungsbereich 658 Elementary Processes in Molecular Switches at Surfaces of the Deutsche Forschungsgemeinschaft, to which we are grateful for financial support. Molecular surfaces at switches contents Molecular switches at surfacesMartin Weinelt and Felix von Oppen Optically and thermally induced molecular switching processes at metal surfacesPetra Tegeder Effects of electron-vibration coupling in transport through single moleculesKatharina J Franke and Jose Ignacio Pascual Vibrational heating in single-molecule switches: an energy-dependent density-of-states approachT Brumme, R Gutierrez and G Cuniberti Reversible switching of single tin phthalocyanine molecules on the InAs(111)A surfaceC Nacci, K Kanisawa and S Fölsch Tuning the interaction between carbon nanotubes and dipole switches: the influence of the change of the nanotube-spiropyran distanceP Bluemmel, A Setaro, C Maity, S Hecht and S Reich Carbon nanotubes as substrates for molecular spiropyran-based switchesE Malic, A Setaro, P Bluemmel, Carlos F Sanz-Navarro, Pablo Ordejón, S Reich and A Knorr Ultrafast dynamics of dithienylethenes differently linked to the surface of TiO2 nanoparticlesLars Dworak, Marc Zastrow, Gehad Zeyat, Karola Rück-Braun and Josef Wachtveitl Switching the electronic properties of Co-octaethylporphyrin molecules on oxygen-covered Ni films by NO adsorptionC F Hermanns, M Bernien, A Krüger, J Miguel and W Kuch STM-switching of organic molecules on semiconductor surfaces: an above threshold density matrix model for 1,5 cyclooctadiene on Si(100)K Zenichowski, Ch Nacci, S Fölsch, J Dokić, T Klamroth and P Saalfrank A switch based on self-assembled thymineFatih Kalkan, Michael Mehlhorn and Karina Morgenstern The growth and electronic structure of azobenzene-based functional molecules on layered crystalsJ Iwicki, E Ludwig, J Buck, M Kalläne, F Köhler, R Herges, L Kipp and K Rossnagel Voltage-dependent conductance states of a single-molecule junctionY F Wang, N Néel, J Kröger, H Vázquez, M Brandbyge, B Wang and R Berndt Molecules with multiple switching units on a Au(111) surface: self-organization and single-molecule manipulationJohannes Mielke, Sofia Selvanathan, Maike Peters, Jutta Schwarz, Stefan Hecht and Leonhard Grill Preparing and regulating a bi-stable molecular switch by atomic manipulationS Sakulsermsuk, R E Palmer and P A Sloan Mixed self-assembled monolayers of azobenzene photoswitches with trifluoromethyl and cyano end groupsDaniel Brete, Daniel Przyrembel, Christian Eickhoff, Robert Carley, Wolfgang Freyer, Karsten Reuter, Cornelius Gahl and Martin Weinelt Reversible electron-induced cis-trans isomerization mediated by intermolecular interactionsCh Lotze, Y Luo, M Corso, K J Franke, R Haag and J I Pascual Transport properties of graphene functionalized with molecular switchesNiels Bode, Eros Mariani and Felix von Oppen

  17. PREFACE: CEWQO Topical Issue CEWQO Topical Issue

    NASA Astrophysics Data System (ADS)

    Bozic, Mirjana; Man'ko, Margarita

    2009-09-01

    This topical issue of Physica Scripta collects selected peer-reviewed contributions based on invited and contributed talks and posters presented at the 15th Central European Workshop on Quantum Optics (CEWQO) which took place in Belgrade 29 May-3 June 2008 (http://cewqo08.phy.bg.ac.yu). On behalf of the whole community took place in Belgrade 29 May-3 June 2008 (http://cewqo08.phy.bg.ac.yu, cewqo08.phy.bg.ac.yu). On behalf of the whole community of the workshop, we thank the referees for their careful reading and useful suggestions which helped to improve all of the submitted papers. A brief description of CEWQO The Central European Workshop on Quantum Optics is a series of conferences started informally in Budapest in 1992. Sometimes small events transform into important conferences, as in the case of CEWQO. Professor Jozsef Janszky, from the Research Institute of Solid State Physics and Optics, is the founder of this series. Margarita Man'ko obtained the following information from Jozsef Janszky during her visit to Budapest, within the framework of cooperation between the Russian and Hungarian Academies of Sciences in 2005. He organized a small workshop on quantum optics in Budapest in 1992 with John Klauder as a main speaker. Then, bearing in mind that a year before Janszky himself was invited by Vladimir Buzek to give a seminar on the same topic in Bratislava, he decided to assign the name 'Central European Workshop on Quantum Optics', considering the seminar in Bratislava to be the first workshop and the one in Budapest the second. The third formal workshop took place in Bratislava in 1993 organized by Vladimir Buzek, then in 1994 (Budapest, by Jozsef Janszky), 1995 and 1996 (Budmerice, Slovakia, by Vladimir Buzek), 1997 (Prague, by Igor Jex), 1999 (Olomouc, Czech Republic, by Zdenek Hradil), 2000 (Balatonfüred, Hungary, by Jozsef Janszky ), 2001 (Prague, by Igor Jex), 2002 (Szeged, Hungary, by Mihaly Benedict), 2003 (Rostock,Germany, by Werner Vogel and Sascha Wallentowitz), 2004 (Trieste, Italy, by Naseem Rahman and Sascha Wallentowitz), 2005 (Bilkent, Ankara, by Alexander Shumovsky), 2006 (Vienna, by Helmut Rauch), 2007 (Palermo, Italy, by Antonino Messina) and 2008 (Belgrade, by Mirjana Bozic). The CEWQO series developed in two directions following the rapid development of quantum optics and the transitional development of the scientific collaboration of Central European researchers with researchers from old and new emerging Central European countries, and from all over the world. The topics discussed at CEWQO 08 were divided into ten groups that aimed to cover the broad scope of modern quantum optics: Fundamental aspects of quantum optics and quantum mechanics Single photons and photon pairs Cavity and circuit QED Atoms in intense fields Neutron, atom and molecular quantum optics Quantum gases and fluids Coherence, entanglement and decoherence Optical properties of condensed matter and nanostructures Open quantum systems and chaos Quantum information processing Central European Workshops on Quantum Optics realize and are consistent with a wider idea, and a social, economical, cultural and political program promoted since 1989 by the Central European Initiative (CEI), the main goal of which was to help transition countries in Central Europe to become closer to the EU. The resulting support of the CEI, first obtained thanks to the scientific reputation, organizing activities, and efforts of Helmut Rauch, has been very important for the organization of the CEWQO in recent years, particularly in 2008. The support of the Sixth and Seventh Framework Programs of the European Commission was also very important. A short review of papers in this topical issue A principal role in this topical issue is played by the photon. Vuletic et al describe the mapping of the photon-polarization state onto a single collective-spin excitation (magnon) shared between two atomic ensembles. A heralded quantum memory based on this mapping is demonstrated. Dodonov derives a formula which predicts a photon generation rate in a cavity due to strong variations of the complex dielectric function in a thin layer near an ideally conducting wall (simulation of the dynamic Casimir effect). Skenderovic reports how photons from two femptosecond laser pulses prepare a large molecule in a coherent superposition of vibrational states. The time evolution of this state is interrogated with a third (delayed) pulse which creates a fourth wave, the signal, giving information on the molecular dynamics. Dimitrova et al present lecture demonstrations of interference and quantum erasing with single photons. By considering electromagnetic energy flow lines as photon paths Davidovic et al explain the emergence of an interference pattern in the process of the accumulation of single photon events behind an interference grating. Atoms in a cavity, atom-atom interactions, interactions of atoms with photons and macroscopic bodies is the next important topic in this topical issue. Khanbekyan et al deal with the problem of the spontaneous emission of an excited atom in a high-Q cavity and investigate the regime when the emitted photon belongs to a wave packet simultaneously located inside and outside the cavity. Sambale et al study the resonant Casimir-Polder potential of an excited atom in front of meta-material half-space and show that for long distances it exhibits attenuated oscillations, while close to the surface the potential becomes attractive or repulsive. Buhmann et al study the nonequilibrium Casimir-Polder force on an atom prepared in an incoherent superposition of internal energy-eigenstates, which is placed in a magnetoelectric environment of nonuniform temperature. Lazarou et al discuss how two atoms, interacting with a single cavity, can be coherently evolved into an entangled state when they are controlled by a sequence of Gaussian pulses, named frequency chirps. Bougouffa et al report on field quantization between two parallel conducting plates (modifications of the decay rate between such plates) and the three-level Jaynes-Cummings dynamics in the single-mode regime. Tomas studies the interaction between two atoms, one excited and the other in its ground state near the interface between two media. It is shown that the nonretarded van der Waals force gets enhanced by almost three orders of magnitude at the surface mode resonance. Vuskovic et al write about the plasma treatment of a bulk Nb surface which is very efficient for producing high-Q factor microwave cavities. Nemeth et al review the theory and experiments of the coherently pumped micromaser. With varied atomic inversion in a coherently pumped micromaser, a sudden switch occurs between two distinctively different field states, with high and low photon numbers. Moi et al show that alkali-metal atoms adsorbed either in organic films or in porous glass are released into the vapor phase (desorbed) under illumination, the action of many photons. Several papers are devoted to matter-wave interference and quantum fluids. By analyzing unavoidable quantum losses as they appear in neutron phase-echo and spin rotation experiments, Rauch concludes that basic quantum irreversibility exists in neutron interferometry. Rauch also shows how entanglement effects in a single particle system demonstrate quantum contextuality, and then argues that a quantum system carries much more information than is usually extracted. The time evolution of the wave function of an atom hit by a photon in a three-grating interferometer is used by Arsenovic et al to interpret the intriguing results of the corresponding experiment by Chapman et al. Grujic et al demonstrate dark Raman resonance due to Ramsey interference in a spatially separated pump and probe laser beams co-propagating through a pure 87Rb vapor cell. Obtained EIT profiles are explained by solving Bloch's equations for an atom in a magnetic field moving through pump and probe laser regions. Gawlik et al present results of experiments on finite-temperature Bose-Einstein condensate of 87Rb atoms in a magnetic trap. In the Thomas-Fermi (TF) regime, the condensate dynamics has a hydrodynamic character. The dynamics of non-TF condensates reflect the interaction between BEC and non-condensed thermal atoms. Atoms in intense fields is the subject of several papers. Gainutdinov et al show that the contribution to the radiative shift of the side bands of the Mollow spectrum is very significant. Using Gell-Mann, Low S-matrix formalism, and QED, Glushkov et al present an approach to study multiphoton processes during the interaction of an atom with a realistic intense laser field. The paper by Khetselius is devoted to two related problems: the calculation of the atomic hyperfine structure of the Li-like ions and an estimation of the effectiveness of the three-step scheme of isotope separation for the case of Cs isotopes. Vvedenskii et al present the results concerning the excitation of a residual quasi-dc current in the plasma, which are based on the solution of the time-dependent Schrödinger equation for the hydrogen atom in a few-cycle laser pulse. Information processing is one of the important aspects of this issue and it is considered in several papers. M Man'ko et al presented a new notion of tomographic entropy and new entropic uncertainty relations applied to the problem of light propagation in optical fibers. Nonlinearity in the quantum-information processing is considered in the paper by Chirkin et al. D'Arrigo et al investigated a very specific semiclassical Hamiltonian model of a quantum memory channel. They evaluated the performance of the three-qubit code error correcting code by means of entanglement fidelity. The fundamental aspects of quantum optics are the subject of several papers, namely, Bell's inequalities are studied in the paper by Andreev, the star-product quantization scheme was discussed by O Man'ko, and probabilistic representation was investigated in the paper by Adam et al. In the paper by V Man'ko et al the diagonal representation of the density operator (usually called P-function of Glauber-Sudarshan) is related to the star-product quantization method and to the tomographic-probability representation of quantum states. Laskowski et al suggest an elegant geometrical criterion for the separability, which is based on the local correlation measurements readily available in the laboratory. Mizrahi describes a method to derive the Pauli-Schrödinger equation starting from a simple model of a qubit carried by a massive particle. By analyzing unavoidable quantum losses as they appear in neutron phase-echo and spin rotation experiments, Rauch concludes that basic quantum irreversibility exists in neutron interferometry. Rauch also shows how entanglement effects in a single particle system demonstrate quantum contextuality, and then argues that a quantum system carries much more information than is usually extracted. Kupczynski advocates various statistical tests which could be used to search for a fine structure in experimental data in order to answer the question: is quantum theory predictably complete? For an ion confined within a Paul trap, Mihalcea constructs an invariant operator based on the Lews and Riesenfeld approach and determines the spectrum of the quasienergy operator. Popov et al construct pair-coherent states of the Barut-Girardello kind for two noninteracting subsystems of pseudoharmonic oscillators and examine their statistical properties in different regions of parameters. The property of entanglement, considered to be the most intriguing property of composite quantum systems, has been an important research subject in recent years. It is considered to be a possible resource for quantum computation and communication. Therefore, a substantial number of papers in this topical issue is devoted to entanglement. Leon et al write that two-photon emission from two atoms initially excited in a common electromagnetic vacuum may generate atom-atom entanglement. Dömötör et al elucidate a connection between entanglement and coherent states. Earlier they proved that in the symmetric subspace of a system of N qubits a pure state is not globally entangled, if and only if, it is a coherent state. Here they extend this proof to a system of N 'quKits' (subsystems of arbitrary finite dimension K). Napoli et al compute exactly localizable entanglement as a function of temperature for the system of three interacting spins in a thermal state. Isar considers entanglement in open quantum dynamics by studying the system of two independent oscillators interacting with the general environment. He proposes some special parameters of the environment that manifest interesting properties (e.g., the environment is entangling initially separable states). Lindén et al study the decay of entanglement in rings of qubits that live in the Markov environment. They use the entanglement of formation as the measure whose time evolution announces (or not) the decay. Jivulescu et al consider the time evolution of a spin-1/2 particle nonuniformly coupled through the Heisenberg interaction to the environment composed of N spins. Considering arbitrary initial conditions the authors determine a numerically manipulative general solution from which information on full dynamics may be extracted. Ferraro et al investigate the entanglement evolution of two qubits interacting with a common environment through a Heisenberg XX mechanism and show that the phenomena of entanglement hidden death and entanglement hidden revival take place. Stochastic processes have been very important in quantum optics. Pascazio et al review and compare three algorithms for the generation of sequences of symmetric stable Levy random variables. They draw conclusions on the efficiency of the algorithms used and on some applications in quantum optics. Hul et al report on the possibilities of explaining the statistical properties of the spectra of irregular quantum systems by invoking the random matrix theory. The authors calculated the spectra, spectral correlation functions, and the distributions of avoided crossings, for two types of idealized model of one-dimensional quantum wires forming a quantum graph. Sirko et al present the experimental study of microwave networks displaying an irregular hexagonal structure. In a sense, these networks model quantum graphs with special properties. Kiss et al consider the recurrence of quantum walks on lattices by studying the properties of the generalized Polya number. The properties of this number are compared for classical and quantum cases. A number of interesting papers are devoted to the optical properties of condensed matter and nanostructures. Gorelik derives analytical expressions for photonic dispersion law in 3D photonic crystals filled by dielectrics or metal. Nemilentsau et al evaluate the photon density of states near a single-wall finite length carbon nanotube. The authors found definite singularities in the density of photon states that may be observable in light-matter interaction, thermal radiation distribution, and micromechanical phenomena related to Casimir forces. Perinova et al pay attention to the interesting relationship between microscopic and macroscopic approaches to the quantization of the electromagnetic field in the medium. They examine the problem of a source atom radiating into a dielectric. Radovanovic et al present an extended approach for estimating the tunneling times through all linear materials, including metamaterials having a negative refractive index. Vasic et al describe the optical design of 2D confined structures with metamaterial layers which is based on coordinate transformations. Using the Green's functions method, Ilic et al analyze the influence of boundaries of the molecular ultrathin film on exciton dispersion law. Jeknic-Dugic proposes the model of optically induced transitions in an electronic subsystem of a bio-molecule that is able to describe relatively slow conformational transitions of a bio-molecule. Stef et al present their goal to grow good quality YbF3-doped and PbF2-codoped CaF2 crystals with high divalent Ytterbium content for investigating the influence of Pb2+ ions on the valence conversion, on the dielectric and optical absorption spectra. Vasile et al present the fabrication and SEM and photoluminescence characterization of zinc gallate doped with Eu and Er ions. The results could be important for photonic applications of spinels. Vasiljevic et al present the process of production of microlenses by irradiation of a tot'hema eosin sensitized gelatin (TESG) layer with a laser beam (2nd Nd:YAG harmonic, 532 nm). Microlenses chemically processed after production with 10% alum solution had near diffraction limited performance. The production and application of microlenses are fast expanding because they are increasingly used in biomedical and general optics. Prizes for the poster presentations Authors under 35 years of age were invited to take part in the poster competition. Two first prizes EX-AEQUOAE were awarded to Zoran Grujic from the Institute of Physics, Belgrade, Serbia, for the poster 'Numerical simulation of Raman-Ramsey effects induced by thermal motion of rubidium atoms' and to Andrey Popov from Altai State Technical University, Bernaul, Russia, for the poster 'Beryllium atoms in intense fields'. The third prize was awarded to Alex Crosse from Imperial College, London, UK, for the poster 'Quantum electrodynamics in absorbing nonlinear media'. Members of the Jury were: Mirjana Bozic (Chairperson), Victor Dodonov, Margarita Man'ko, Helmut Rauch, Saverio Pascazio, Richard Tanas and Philip Walther. Sponsors of the awards were the Institute of Physics, Belgrade, European Physical Journal (EPJ) and John Wiley and Sons. CEWQO 2009 and 2010 The 16th Central European Workshop on Quantum Optics was held in Turku, Finland, 23-27 May 2009. CEWQO09 was chaired by Professor Kalle-Antti Suominen (http://www.congress.utu.fi/cewqo2009). The conference site is the new ICT building at chaired by Professor Kalle-Antti Suominen (http://www.congress.utu.fi/cewqo2009, www.congress.utu.fi/cewqo2009). The conference site was the new ICT building at the University of Turku campus area and the Viking Line ferry boat. Turku is the central city of historical Finland established on the mouth of the river Aura in the 13th century. It is the birthplace of Finnish academic life, since the Academy of Turku was established there in 1640. In 2011, Turku will be one of the cultural capitals of Europe. The city has a strong maritime tradition and is shielded from the Baltic sea by a large and beautiful archipelago. The 17th Central European Workshop on Quantum Optics will be held in 2010 in St Andrews, UK. It will be chaired by Professors Ulf Leonhardt and Natalia Korolkova from the School of Physics and Astronomy, University of St Andrews. St Andrews is home to the first university of Scotland, the third-oldest in the English-speaking world, and is the home of golf. It remains a charming, eccentric seaside town that is sufficiently secluded - the ideal place for a stimulating and thought-provoking conference.

  18. FOREWORD: The 70th birthday of Professor Stig Stenholm The 70th birthday of Professor Stig Stenholm

    NASA Astrophysics Data System (ADS)

    Suominen, Kalle-Antti

    2010-09-01

    It is not easy to assess, or even to describe correctly a long and distinguished career that started about the time when I was born. In 1964 Stig Stenholm got both an engineering degree at the Helsinki University of Technology (HUT), and an MSc degree (in Mathematics) at the University of Helsinki. The two degrees demonstrate Stig's ability to understand both complex mathematics and experimental physics. Statistical physics or rather, quantum liquids, was the field in which Stig got his DPhil at Oxford in 1967, under the guidance of Dirk ter Haar. It is interesting that together they worked on studying fermions in a bosonic background [1]; at the time this meant, of course, 3He atoms as impurities in 4He liquid, but nowadays one would immediately connect such systems to the physics of cold atomic gases. The postdoctoral period in 1967-1968 at Yale University brought Stig in contact with Willis Lamb and laser physics [2]. Back in Finland, Stig's career in the 1970s was dominated by theoretical studies of gas lasers, especially pressure and collision effects on spectral lines and saturation spectroscopy, together with his first PhD student, Rainer Salomaa. A professorship at the University of Helsinki came in 1974, and in 1980 an important era started as Stig became the scientific director of the Research Institute for Theoretical Physics (TFT). At that time he also developed the semiclassical theory of laser cooling especially with Juha Javanainen. The laser spectroscopy work led to a textbook in 1984 [3], and the semiclassical laser cooling theory was summarized in a review article in 1986 [4]. These were not, of course, his only interests, as he also worked on free-electron lasers, ring-laser gyroscopes, multiphoton processes and quantum amplifiers. In an article written in 1990 in honour of Olli Lounasmaa [5], the founder of the famous Low Temperature Laboratory at HUT, Stig mentions that one of his most memorable achievements was acting as a bridge between the Western and Soviet laser cooling communities. In neutral Finland, accessible to both parties, he organized informal workshops that crucially sped the development of laser cooling. The importance of these meetings is highlighted in Bill Phillips' Nobel lecture in 1997 [6]. However, as the emphasis in laser cooling moved from a semiclassical description to quantum theory, Stig started to look for new avenues of research. My contact with Stig came when I went to see him for an MSc thesis topic. This involved polarization spectroscopy and modelling of an experiment performed by the laser spectroscopy group (Birger Ståhlberg) at the University of Helsinki. Without knowing anything about quantum optics I then found myself immediately in one of the Finnish-Soviet workshops on quantum electronics in the small town of Porvoo slightly east of Helsinki. There I met people like Juha Javanainen, Peter Knight, Axel Schenzle and Vladimir Chebotayev, and my own career in quantum optics began, working on the mathematics of the Landau-Zener model and how to apply it and other such models in molecular excitation by femtosecond pulses for my PhD thesis. This work was done together with Barry Garraway, who was a postdoc in Helsinki in the early 1990s. The Finnish-Soviet meetings continued for a while, and in 1990 we even got to travel to Novosibirsk (and back, too). During its existence (1964-1996), the Research Institute of Theoretical Physics (TFT) had a tremendous impact on physics in Finland. Short and long stays by visitors provided a unique and high-level environment for local researchers, the research fields covered a wide range of physics, and for many Finns returning from abroad it provided a place to stay until something more permanent turned up. Thus many researchers who later became professors had, at some point in their career, a connection with TFT. As a director Stig was very broad-minded and without this the happy atmosphere of TFT could not have existed. In the 1980s young researchers such as Marc-Andre Dupertuis and Steve Barnett worked with Stig at TFT, and in the 1990s it was the turn of Barry Garraway, Ilkka Tittonen and Nikolay Vitanov among others. For his work in 1992-1997 Stig Stenholm received the prestigious Academy of Finland Professorship which provided him with valuable research funds. My graduation in 1992 was followed by Mackillo Kira in 1995 and Päivi Törmä in 1996. Following developments in the field, in the mid-1990s Stig started to work on Bose-Einstein condensation and quantum information. Later he had a Humboldt fellowship, with stays in Germany shared by the Universities at Konstanz (Jürgen Mlynek) and Ulm (Wolfgang Schleich). Unfortunately, the University of Helsinki decided to replace TFT and a corresponding experimental particle physics institute with a new institute, which was mostly seen as the Finnish front-end for CERN collaboration; in 1997 the Helsinki Institute of Physics (HIP) was started. Although the activities of TFT still existed in the theory section of HIP, many things and especially the atmosphere were changed and in 1997 this partly led Stig to accept a position at the Royal Institute of Technology in Stockholm, Sweden, where two of his Finnish students, Patrik Öhberg and Erika Andersson graduated shortly after the move. I moved to HIP at the time, but left for a position in Turku in 2000, and the quantum optics project was finally switched off at HIP in 2003—only later it was found that quantum optics had provided the Institute with its most cited papers, propelling it into the top 5 percent most cited institutes in its field (especially thanks to Norbert Lütkenhaus and his work on quantum cryptography). The time in Stockholm was fruitful for Stig scientifically, but he also became a member of the Royal Swedish Academy of Sciences, and although Nobel committee papers remain secret for 50 years, it is likely that he had a hand in its activities. In 2005 we jointly published a textbook on quantum information [7] and in Stockholm he had, again, very successful postdocs such as Ulf Leonhardt. Finally, in 2005, Stig Stenholm retired, although he is still active, writing papers, taking part in conferences and making research visits. We honoured his 70th birthday at the CEWQO2009 conference, and hope that the future provides us with further opportunities for such events. Looking at the obituary of Dirk ter Haar, I see that his style with students reminds me of Stig's approach. In my opinion, Stig expects independence and initiative from a student, giving perhaps a broad topic in which the student is expected to find his or her own way, whilst working perhaps with a postdoc. Juha Javanainen has talked about the 'sink or swim' style (not referring to Stig, though). There is a famous series of children's books about Moomin trolls by Tove Jansson (another Swedish-speaking Finn like Stig). In one of them, the Moomin find in early spring a small flower in a patch of land uncovered by snow, pushing its way up. One of them wants to cover it against frost during the night, but another says 'Don't, it'll fare better later if it has some difficulties at first'. At CEWQO2009 Stig gave the full list of his finished PhD students: Rainer Salomaa (1973), Temba Dlodlo (1980), Juha Javanainen (1980), Markus Lindberg (1985), Matti Kaivola (1985), Birger Ståhlberg (1985), Kalle-Antti Suominen (1992), Mackillo Kira (1995), Päivi Törmä (1996), Asta Paloviita (1997), Patrik Öhberg (1998), Martti Havukainen (1999), Erika Andersson (2000), Pawel Piwnicki (2001), Åsa Larson (2001), Markku Jääskeläinen (2003), and Jonas Larson (2005). One should also mention Erkki Kyrölä, who eventually graduated at Rochester and Olli Serimaa, who never graduated but published some important early-stage laser cooling work. As a final note I must mention a passion that Stig and I share, namely books. I have nearly 400 professional physics and mathematics books, but I am certain that the size of Stig's library exceeds this by far. And this passion is not solely limited to professional books, as one can see, for example, from the references in Stig's article for these proceedings. His interests cover philosophy, history, science fiction and many other topics, and more importantly, the books in his library also get read. In modern times of narrow specialization, high efficiency and h-index, his approach to science and culture sets an example that is worth following. References [1] Stenholm S and ter Haar D 1968 Dilute mixtures of 3He in superfluid 4He Physica 38 133 [2] Stenholm S and Lamb W E 1969 Semiclassical theory of a high-intensity laser Phys. Rev. 181 618 [3] Stenholm S 1984 The Foundations of Laser Spectroscopy (New York: Wiley) [4] Stenholm S 1986 The semiclassical theory of laser cooling Rev. Mod. Phys. 58 699 [5] Stenholm S 1998 Physics that matters Arkhimedes 42 197 [6] Phillips W D 1990 Nobel lecture: laser cooling and trapping of neutral atoms Rev. Mod. Phys. 70 721 [7] Stenholm S and Suominen K-A 2005 Quantum Approach to Informatics (New York: Wiley)

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