DEVELOPMENTS AT U.S. EPA IN ADDRESSING UNCERTAINTY IN RISK ASSESSMENT

EPA Science Inventory

An emerging trend in risk assessment is to be more explicit about uncertainties, both during the analytical procedures and in communicating results. In February 1 992, then-Deputy EPA Administrator Henry Habicht set out Agency goals in a memorandum stating that the Agency will "p...

Impact of Alleged Russian Cyber Attacks

DTIC Science & Technology

2009-05-01

security. 15. SUBJECT TERMS Cyber Security, Cyber Warfare , Estonia, Georgia, Russian Federation Cyber Strategy, Convention on Cybercrime, NATO Center...Federation ......................................................................................... 33  X.  The Future of Russian Cyber Warfare ................................................................... 39...Issue 15.09); Binoy Kampmark, Cyber Warfare Between Estonia And Russia, (Contemporary Review: Autumn, 2003), p 288-293; Jaak Aaviksoo, Address by the

Evaluation of continuing education of family health strategy teams for the early identification of suspected cases of cancer in children.

PubMed

Costa, Ana Maria Aranha Magalhaes; Magluta, Cynthia; Gomes Junior, Saint Clair

2017-09-07

This study evaluated the influence of continuing education of family health strategy teams by the Ronald McDonald Institute program on the early diagnosis of cancer in children and adolescents. The study applied Habicht's model to evaluate the adequacy and plausibility of continuing education by using as outcome the number of children with suspected cancer who were referred to the hospital of references in the 1 year before and 1 year after intervention and the number of patients referred by intervention group and control group family health strategy teams. Medical records from each hospital of reference were used to collect information of suspect cases of cancer. Descriptive analyses were performed using frequencies and mean values. Chi-square tests were used to assess statistically significant differences between the groups and periods by using p-values < 0.05. The results showed a 30.6% increase in the number of children referred to the hospital of reference for suspected cancer in the post-intervention period; in addition, the family health strategy teams that underwent the intervention referred 3.6 times more number of children to hospital of references than did the control group. Only the intervention group showed an increase in the number of confirmed cases. This evaluation of a continuing education program for early identification of pediatric cancer showed that the program was adequate in achieving the established goals and that the results could be attributed to the program.

Characterisation of impacts on the environment of an idealised offshore wind farm foundation, under waves and the combination of waves and currents

NASA Astrophysics Data System (ADS)

García-Hermosa, Isabel; Abcha, Nizar; Brossard, Jérôme; Bennis, Anne-Claire; Ezersky, Alexander; Gross, Marcus; Iglesias, Gregorio; Magar, Vanesa; Miles, Jon; Mouazé, Dominique; Perret, Gaële; Pinon, Grégory; Rivier, Aurélie; Rogan, Charlie; Simmonds, David

2015-04-01

system photographing the bed (Marin & Ezersky, 2007, and Jarno-Druaux et al., 2004). Velocity fields, and flow structures around the cylinder at low KC numbers (KC~1) were characterised and parameters such as vorticity, turbulent kinetic energy and bed shear stresses derived where possible. During the experiments vortex structures with a horizontal axis were observed in the vicinity of the cylinder and the bed even at low KC. The Keulegan-Carpenter number (KC) is defined as: KC = UmT- D, where Um is the bottom orbital velocity, T the peak period and D the pile diameter. As part of the project, the findings from the experiments fed into a regional numerical modelling (Rivier et al., 2014) to improve parametrisation of the representation of the within-cell processes (local to the mast). References García-Hermosa, M. I., Brossard, J., Cohen, Z., Perret, G. (2014). Experimental characterisation of wave induced flow fields due to an offshore wind farm mast. First International Conference on Renewable Energies Offshore (RENEW) Lisbon, Portugal. November 2014. Gunnoo, H., Abcha, N., Mouazé, D., Ezersky, A., García-Hermosa, M. I. (2014). Laboratory simulation of resonance amplification of the hydrodynamic fields in the vicinity of wind farm masts. Proceedings of the First International Conference on Renewable Energies Offshore (RENEW) Lisbon, Portugal. November 2014. Jarno-Druaux, A., Brossard, J., Marin, F. (2004). Dynamical evolution of ripples in a wave channel, European Journal of Mechanics B/Fluids 23: 695-708. Marin, F. and Ezersky, A. B. (2007). Formation dynamics of sand bedforms under solitons and bound states of solitons in a wave flume used in resonant mode. European Journal of Mechanics - B/Fluids, Elsevier, 2008, 27 (3), pp.251-267. Rivier, A., Bennis, A.-C., Pinon, G., Gross, M., Magar, V. (2014). Regional numerical modelling of offshore monopile wind turbine impacts on hydrodynamics and sediment transport. Proceeding of the 1st International Conference on

The ecophysiology of sulfur isotope fractionation by sulfate reducing bacteria in response to variable environmental conditions

NASA Astrophysics Data System (ADS)

Leavitt, W.; Bradley, A. S.; Johnston, D. T.; Pereira, I. A. C.; Venceslau, S.; Wallace, C.

2014-12-01

Microbial sulfate reducers (MSR) drive the Earth's biogeochemical sulfur cycle. At the heart of this energy metabolism is a cascade of redox transformations coupling organic carbon and/or hydrogen oxidation to the dissimilatory reduction of sulfate to sulfide. The sulfide produced is depleted in the heavier isotopes of sulfur relative to sulfate. The magnitude of discrimination (fractionation) depends on: i) the cell-specific sulfate reduction rate (csSRR, Kaplan & Rittenberg (1964) Can. J. Microbio.; Chambers et al. (1975) Can. J. Microbio; Sim et al. (2011) GCA; Leavitt et al. (2013) PNAS), ii) the ambient sulfate concentration (Harrison & Thode (1958) Research; Habicht et al. (2002) Science; Bradley et al. in review), iii) both sulfate and electron donor availability, or iv) an intrinsic physiological limitation (e.g. cellular division rate). When neither sulfate nor electron donor limits csSRR a more complex function relates the magnitude of isotope fractionation to cell physiology and environmental conditions. In recent and on-going work we have examined the importance of enzyme-specific fractionation factors, as well as the influence of electron donor or electron acceptor availability under carefully controlled culture conditions (e.g. Leavitt et al. (2013) PNAS). In light of recent advances in MSR genetics and biochemistry we utilize well-characterized mutant strains, along with a continuous-culture methodology (Leavitt et al. (2013) PNAS) to further probe the fractionation capacity of this metabolism under controlled physiological conditions. We present our latest findings on the magnitude of S and D/H isotope fractionation in both wild type and mutant strains. We will discuss these in light of recent theoretical advances (Wing & Halevy (2014) PNAS), examining the mode and relevance of MSR isotope fractionation in the laboratory to modern and ancient environmental settings, particularly anoxic marine sediments.

EDITORIAL: Towards the next node in downsized devices Towards the next node in downsized devices

NASA Astrophysics Data System (ADS)

Demming, Anna

2010-02-01

-beam-induced-deposition techniques and the state of play of the latest research for tackling the problem of impurities posed by this technique. In this issue Stefan Habicht and colleagues look at the effects of strain on the silicidation process in nickel silicide nanowires [7]. The study focuses on the contact conductivity and resistivity, and demonstrates impressively low resisitvities for NiSi/Si contacts for silicon-on-insulator and strained silicon-on-insulator nanowires compared with planar structures. The researchers also identify a reduction in the resistivity of uniaxially strained nanowires, which they attribute to the improved mobility of the electrons. Also in this issue, Stefen Münch and colleagues in Germany and Sweden use real-time photoluminescence spectroscopy to investigate the effect of HfO2 surface capping by atomic layer deposition on the optical properties of InP nanowires [8]. Hafnium oxide has a high dielectric constant and acts as a gate oxide, facilitating applications of the nanowires in field effect transistors. The work reports details of how different pretreatments and deposition parameters affect the optical properties of the nanowires, and demonstrates how real-time photoluminescence spectroscopy can provide an attractive method for allowing direct optical access to the interface properties. The surface treatment can also be applied to other III-V material systems such as InAs. Without a doubt, maintaining the rate of progress in terms of the cost and size of transistors poses some significant challenges as we continue to push towards further electronic miniaturization. What is also clear is how these challenges are providing ample inspiration for technological innovation and the study of fundamental properties of systems at the nanoscale. References [1] Ijima S 1991 Nature 354 56 [2] Che J, Çagin T and Goddard W A III 2000 Nanotechnology 11 65-9 [3] Sidorov A, Mudd D, Dumanasekara G, Ouseph P J, Jayanthi C S and Wu S-Y 2009 Nanotechnology 20 055611 [4] Guen Y et

Prediction of bedload sediment transport for heterogeneous sediments in shape

NASA Astrophysics Data System (ADS)

Durafour, Marine; Jarno, Armelle; Le Bot, Sophie; Lafite, Robert; Marin, François

2015-04-01

agreement is found for the non-uniform site between measured fluxes and predictions given by the Wu et al. (2000) model. However, some discrepancies still remain, especially for granules. Hundreds of pictures of grains composing the sediment cover and the bedload discharges are performed. Particle shapes are statistically characterized by three 2D coefficients (circularity, roundness and elongation) after an image processing with the ImageJ software. Present results show a preferential transport of the most circular sediment particles available for transport and reveal that the consideration of particle shape, through the integration of the circularity index in formulations, enhanced the estimations of bedload rates. A new adjustment of the Wu et al. (2000) formula is proposed, which improves significantly the model predictions, especially for granules. Durafour M, Jarno A, Le Bot S, Lafite R, Marin F (2014) Bedload transport for heterogeneous sediments. Environmental Fluid Mechanics. doi: 10.1007/s10652-014-9380-1