Effects of conversion of mangroves into gei wai ponds on sediment heavy metals accumulation in tidal flat estuary, South China

NASA Astrophysics Data System (ADS)

Li, R.; Qiu, G.; Chai, M.; Li, R.

2017-12-01

Gei wai ponds act as important component in mangrove ecosystem, but the conversion of mangroves into gei wai ponds and its ecological function on heavy metal accumulation is still not clear. The study quantified the sediment heavy metal concentration and speciation in gei wai pond, Avicennia marina marsh and mudflat in Futian mangrove wetlands, South China. The results showed that gei wai pond acidified the sediment and reduced its fertility due to reduced pH, electronic conductivity (EC) and total organic carbon (TOC) compared to A. marina marsh and mudflat. The concentrations of Cd, Cu, Zn and Pb at all depth in gei wai pond sediment were also lower than other sites, indicating reduced storage function on heavy metals. Multiple analysis implied that heavy metals in all sites could be attributed to anthropogenic sources, with Cr as natural and anthropogenic sources in gei wai pond. Gei wai pond sediment had lower heavy metal pollution based on multiple evaluation methods, including potential ecological risk coefficient (Eir), potential ecological risk index (RI), geo-accumulation index (Igeo), mean PEL quotients (m-PEL-q), pollution load index (PLI), mean ERM quotients (m-ERM-q) and total toxic unit (∑TU). Heavy metal speciation analysis indicated that gei wai pond improved the conversion from the immobilized Cd and Cr to the mobilized fraction. SEM-AVS analysis indicated no adverse toxicity occurred in all sites, and the role of TOC in relieving sediment heavy metal toxicity of gei wai pond is limited.

Independent Examination of the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV): What Does the WAIS-IV Measure?

ERIC Educational Resources Information Center

Benson, Nicholas; Hulac, David M.; Kranzler, John H.

2010-01-01

Published empirical evidence for the Wechsler Adult Intelligence Scale--Fourth Edition (WAIS-IV) does not address some essential questions pertaining to the applied practice of intellectual assessment. In this study, the structure and cross-age invariance of the latest WAIS-IV revision were examined to (a) elucidate the nature of the constructs…

A comparison of Boolean-based retrieval to the WAIS system for retrieval of aeronautical information

NASA Technical Reports Server (NTRS)

Marchionini, Gary; Barlow, Diane

1994-01-01

An evaluation of an information retrieval system using a Boolean-based retrieval engine and inverted file architecture and WAIS, which uses a vector-based engine, was conducted. Four research questions in aeronautical engineering were used to retrieve sets of citations from the NASA Aerospace Database which was mounted on a WAIS server and available through Dialog File 108 which served as the Boolean-based system (BBS). High recall and high precision searches were done in the BBS and terse and verbose queries were used in the WAIS condition. Precision values for the WAIS searches were consistently above the precision values for high recall BBS searches and consistently below the precision values for high precision BBS searches. Terse WAIS queries gave somewhat better precision performance than verbose WAIS queries. In every case, a small number of relevant documents retrieved by one system were not retrieved by the other, indicating the incomplete nature of the results from either retrieval system. Relevant documents in the WAIS searches were found to be randomly distributed in the retrieved sets rather than distributed by ranks. Advantages and limitations of both types of systems are discussed.

Impact of Radiotherapy on Fertility, Pregnancy, and Neonatal Outcomes in Female Cancer Patients

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wo, Jennifer Y.; Viswanathan, Akila N.

Purpose: Radiation has many potential long-term effects on cancer survivors. Female cancer patients may experience decreased fertility depending on the site irradiated. Oncologists should be aware of these consequences and discuss options for fertility preservation before initiating therapy. Methods and Materials: A comprehensive review of the existing literature was conducted. Studies reporting the outcomes for female patients treated with cranio-spinal, abdominal, or pelvic radiation reporting fertility, pregnancy, or neonatal-related outcomes were reviewed. Results: Cranio-spinal irradiation elicited significant hormonal changes in women that affected their ability to become pregnant later in life. Women treated with abdomino-pelvic radiation have an increased ratemore » of uterine dysfunction leading to miscarriage, preterm labor, low birth weight, and placental abnormalities. Early menopause results from low-dose ovarian radiation. Ovarian transposition may decrease the rates of ovarian dysfunction. Conclusions: There is a dose-dependent relationship between ovarian radiation therapy (RT) and premature menopause. Patients treated with RT must be aware of the impact of treatment on fertility and explore appropriate options.« less

The role of interventional radiology in abdominopelvic trauma

PubMed Central

Ierardi, Anna Maria; Duka, Ejona; Lucchina, Natalie; Floridi, Chiara; De Martino, Alessandro; Donat, Daniela; Fontana, Federico

2016-01-01

The management of trauma patients has evolved in recent decades owing to increasing availability of advanced imaging modalities such as CT. Nowadays, CT has replaced the diagnostic function of angiography. The latter is considered when a therapeutic option is hypothesized. Arterial embolization is a life-saving procedure in abdominopelvic haemorrhagic patients, reducing relevant mortality rates and ensuring haemodynamic stabilization of the patient. Percutaneous transarterial embolization has been shown to be effective for controlling ongoing bleeding for patients with high-grade abdominopelvic injuries, thereby reducing the failure rate of non-operative management, preserving maximal organ function. Surgery is not always the optimal solution for stabilization of a patient with polytrauma. Mini-invasivity and repeatability may be considered as relevant advantages. We review technical considerations, efficacy and complication rates of hepatic, splenic, renal and pelvic embolization to extrapolate current evidence about transarterial embolization in traumatic patients. PMID:26642310

Are Cross-National Differences in IQ Profiles Stable? A Comparison of Finnish and U.S. WAIS Norms

ERIC Educational Resources Information Center

Roivainen, Eka

2013-01-01

To study the concept of national IQ profile, we compared U.S. and Finnish WAIS, WAIS-R, and WAIS III nonverbal and working memory subtest norms. The U.S. standardization samples had consistently higher scores on the Coding and Digit span subtests, while the Finnish samples had higher scores on the Block design subtest. No stable cross-national…

The Prognostic Value of the Work Ability Index for Sickness Absence among Office Workers.

PubMed

Reeuwijk, Kerstin G; Robroek, Suzan J W; Niessen, Maurice A J; Kraaijenhagen, Roderik A; Vergouwe, Yvonne; Burdorf, Alex

2015-01-01

The work ability index (WAI) is a frequently used tool in occupational health to identify workers at risk for a reduced work performance and for work-related disability. However, information about the prognostic value of the WAI to identify workers at risk for sickness absence is scarce. To investigate the prognostic value of the WAI for sickness absence, and whether the discriminative ability differs across demographic subgroups. At baseline, the WAI (score 7-49) was assessed among 1,331 office workers from a Dutch financial service company. Sickness absence was registered during 12-months follow-up and categorised as 0 days, 0

Influence of the West Antarctic Ice Sheet and its collapse on the wind and precipitation regimes of the Ross Embayment

NASA Astrophysics Data System (ADS)

Seles, D.; Kowalewski, D. E.

2015-12-01

Marine Isotope Stage 31 (MIS 31) is a key analogue for current warming trends yet the extent of the East Antarctic Ice Sheet (EAIS) and the West Antarctic Ice Sheet (WAIS) during this interglacial remains unresolved. Inconsistencies persist between offshore records (suggesting the instability of WAIS) and McMurdo Dry Valley (MDV) terrestrial datasets (indicating long-term ice sheet stability). Here we use a high-resolution regional scale climate model (RegCM3_Polar) to reconstruct paleoclimate during MIS 31 (warm orbit, 400 ppm CO2) and assess changes in precipitation and winds (including katabatic) with WAIS present versus WAIS absent. The MIS 31 scenario with WAIS present resulted in minimal changes in wind magnitude compared with current climate conditions. With WAIS absent, the model predicts a decrease in coastal and highland monthly mean average wind velocities. The greatest rates of snowfall remain along the coast but shift towards higher latitudes with the interior continent remaining dry when WAIS is removed. Focusing on the Ross Embayment, this decreased monthly mean wind velocity and shift of winds to the east indicate a greater influence of offshore winds from the Ross Sea, enabling the increase of precipitation southward along the Transantarctic Mountains (TAM) (i.e. MDV). The apparent decrease of katabatic winds with no WAIS implies that offshore winds may be responsible for bringing the warmer, wetter air into the TAM. The change in wind and precipitation in the Ross Embayment and specifically the MDV highlights the impact of WAIS on Antarctic climate and its subsequent influence on the mass balance of peripheral EAIS domes (i.e. Taylor Dome). Modeling suggests that if WAIS was absent during MIS 31, we would expect (1) greater accumulation at such domes and (2) MDV terrestrial records that reflect a wetter climate, and (3) weaker winds suggesting possibly lower ablation/erosion rates compared to if WAIS was present.

Psychometric properties of the Thai version of the work ability index (Thai WAI).

PubMed

Kaewboonchoo, Orawan; Ratanasiripong, Paul

2015-01-01

The purpose of this research was to develop and test the psychometric properties of the Thai version of the Work Ability Index (WAI). Forward translation and back-translation of the WAI were performed by seven bilingual professionals to ensure that the Thai WAI was culturally relevant and conceptually accurate. To ensure generalizability of the Thai WAI, a sample of 2,744 Thai workers from 19 different enterprises in five regions of Thailand completed the Thai version of the WAI along with the General Health Questionnaire. The 19 enterprises were from the following industries: canned food, snack food, cooking oil, footwear, pharmaceutical, ceramics, toy, steel, petrochemical, and auto parts. The results from exploratory factor analysis supported a 3-factor model, accounting for 53.49% of the total variance. The results also provided evidence for adequate test-retest reliability and internal consistency of the Thai WAI. The internal consistency of the Thai WAI was found to be slightly low due to the newness of the concept of work ability, which is not a common term used in the Thai language; therefore, explanation of the meaning of work ability is needed to increase understanding of workers. By providing early recognition of workers' health risks as well as risks of early termination, the WAI can help Thai human resources managers respond better to the needs of workers and be proactive in their efforts to retain workers in their organizations. Occupational health professionals could also utilize the WAI to evaluate the work ability of Thai workers in order to help organizations recognize early signs of their workers' health risks and possible early terminations and respond appropriately.

Measurement properties of the Brazilian version of the Working Alliance Inventory (patient and therapist short-forms) and Session Rating Scale for low back pain.

PubMed

Araujo, Amanda Costa; Filho, Rúben Negrão; Oliveira, Crystian B; Ferreira, Paulo H; Pinto, Rafael Z

2017-01-01

In the low back pain (LBP) field, therapeutic alliance is considered a non-specific factor of interventions associated with improvements in clinical outcomes. However, there is a paucity of studies aimed to evaluate measurement properties of tools used to objectively quantify the alliance between therapist and patients, such as the Working Alliance Inventory (WAI) and Session Rating Scale (SRS). To translate and cross-culturally adapt the short-form version of WAI - therapist and SRS into Brazilian Portuguese; to investigate the measurement properties, of the WAI-Patient, WAI-Therapist and SRS in patients with LBP and their physical therapists, respectively. One hundred patients with LBP and 18 physical therapists were recruited from physical therapy clinics in Brazil. Therapeutic alliance measures were collected at the initial assessment, prior to the second session, and at 2-month follow-up. The measurement properties investigated were reproducibility, internal consistency, ceiling/floor effects and responsiveness. Although WAI-Patient, WAI-Therapist and SRS were considered to have acceptable test-retest reliability (ICC2,1 > 0.70), these questionnaires showed problems with other measurement properties. WAI-Patient showed problems with internal consistency (i.e. Cronbach's alpha < 0.70 for all subscales). Presence of ceiling effect (i.e. > 15% of participants with the maximum score) and poor internal responsiveness were found for the WAI-Patient (Effect size = 0.15; 84% CI: 0.04 to 0.29) and for the SRS (Effect size = 0.05; 84% CI: -0.22 to 0.11). The WAI-Therapist revealed slightly better measurement properties. We identified psychometric limitations with most measurement properties of the WAI questionnaires and SRS. Future studies are needed to refine these tools.

Shortened version of the work ability index to identify workers at risk of long-term sickness absence.

PubMed

Schouten, Lianne S; Bültmann, Ute; Heymans, Martijn W; Joling, Catelijne I; Twisk, Jos W R; Roelen, Corné A M

2016-04-01

The Work Ability Index (WAI) identifies non-sicklisted workers at risk of future long-term sickness absence (LTSA). The WAI is a complicated instrument and inconvenient for use in large-scale surveys. We investigated whether shortened versions of the WAI identify non-sicklisted workers at risk of LTSA. Prospective study including two samples of non-sicklisted workers participating in occupational health checks between 2010 and 2012. A heterogeneous development sample (N= 2899) was used to estimate logistic regression coefficients for the complete WAI, a shortened WAI version without the list of diseases, and single-item Work Ability Score (WAS). These three instruments were calibrated for predictions of different (≥2, ≥4 and ≥6 weeks) LTSA durations in a validation sample of non-sicklisted workers (N= 3049) employed at a steel mill, differentiating between manual (N= 1710) and non-manual (N= 1339) workers. The discriminative ability was investigated by receiver operating characteristic analysis. All three instruments under-predicted the LTSA risks in both manual and non-manual workers. The complete WAI discriminated between individuals at high and low risk of LTSA ≥2, ≥4 and ≥6 weeks in manual and non-manual workers. Risk predictions and discrimination by the shortened WAI without the list of diseases were as good as the complete WAI. The WAS showed poorer discrimination in manual and non-manual workers. The WAI without the list of diseases is a good alternative to the complete WAI to identify non-sicklisted workers at risk of future LTSA durations ≥2, ≥4 and ≥6 weeks. © The Author 2015. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

Long-Term IQ Stability Using the WISC-IV and WAIS-IV among a Sample of Special Education Students

ERIC Educational Resources Information Center

Spector, Hayley

2013-01-01

The present study investigated the stability of scores on the WISC-IV and WAIS-IV over an approximate six-year period. Previous research using older versions of the WISC and WAIS have suggested that these scales demonstrate strong stability of scores. Since research that has compared the stability of scores between the WISC-IV and the WAIS-IV is…

Work Ability Index (WAI) and its health-related determinants among Iranian farmers working in small farm enterprises.

PubMed

Rostamabadi, Akbar; Mazloumi, Adel; Rahimi Foroushani, Abbas

2014-01-01

This study aimed to determine the Work Ability Index (WAI) and examine the influence of health dimensions and demographic variables on the work ability of Iranian farmers working in small farm enterprises. A cross-sectional study was conducted among 294 male farmers. The WAI and SF-36 questionnaires were used to determine work ability and health status. The effect of demographics variables on the work ability index was investigated with the independent samples t-test and one-way ANOVA. Also, multiple linear regression analysis was used to test the association between the mean WAI score and the SF-36 scales. The mean WAI score was 35.1 (SD=10.6). One-way ANOVA revealed a significant relationship between the mean WAI and age. Multiple linear regression analysis showed that work ability was more influenced by physical scales of the health dimensions, such as physical function, role-physical, and general health, whereas a lower association was found for mental scales such as mental health. The average WAI was at a moderate work ability level for the sample population of farmers in this study. Based on the WAI guidelines, improvement of work ability and identification of factors affecting it should be considered a priority in interventional programs. Given the influence of health dimensions on WAI, any intervention program for preservation and promotion of work ability among the studied farmers should be based on balancing and optimizing the physical and psychosocial work environments, with a special focus on reducing physical work load.(J Occup Health 2014; 56: 478-484).

Pain, fatigue and hand function closely correlated to work ability and employment status in systemic sclerosis.

PubMed

Sandqvist, Gunnel; Scheja, Agneta; Hesselstrand, Roger

2010-09-01

To identify factors, individual and work related, influencing work ability, and to assess the association between work ability and employment status, activities of daily life (ADLs) and quality of life in patients with SSc. Fifty-seven consecutive patients (53 females/4 males) with SSc (47 lcSSc/10 dcSSc) were included. Median age was 58 [interquartile range (IQR) 47-62] years and disease duration 14 (9-19) years. The patients were assessed for socio-demographic characteristics, disease parameters, symptoms, work ability, empowerment and adaptations in a workplace, social support, ADLs and quality of life. Work ability, assessed with the Work Ability Index (WAI) could be evaluated in 48 of 57 patients. The correlation between employment status and WAI was good (r(s) = 0.79, P < 0.001). Thirteen patients had good or excellent WAI, 15 had less good and 20 had poor WAI. There were no significant differences between subgroups of WAI and socio-demographic characteristics, disease duration or degree of skin and lung involvement. However, patients with good WAI expressed milder perceived symptoms (pain, fatigue and impaired hand function; P < 0.001). Patients with better WAI had better competence (P < 0.001), better possibility of adaptations at work (P < 0.01) and impact at work (P < 0.01) than those with poorer WAI. In SSc, pain, fatigue and impaired hand function have a dominant impact on the WAI. Employment interventions should include support in job adaptations as well as self-management strategies to help patients deal with pain and fatigue and to enhance the confidence to perform their work.

A Study on Work Ability Index and Physical Work Capacity on the Base of Fax Equation VO(2) Max in Male Nursing Hospital Staff in Isfahan, Iran.

PubMed

Habibi, Ehsanollah; Dehghan, Habibollah; Zeinodini, Mohhamad; Yousefi, Hosseinali; Hasanzadeh, Akbar

2012-11-01

The purpose of this research is to establish the ability of employees by work ability index (WAI), physical work capacity (PWC), and finding the correlation between them. Establishing the PWC index with attention to WAI values for the purpose of saving in costs and time of PWC measurements is another aim of this project. The present research is an analytic cross-sectional and one-trail study. The study population consists of 228 randomly selected registered nurses from hospitals in Isfahan (Iran). The WAI and PWC were established through WAI questionnaire and Fax equation and by using ergometer bicycle, respectively. The resulting data were analyzed using SPSS 16 software. Average WAI and PWC among the study population were 38.25±4.4 and 4.45±0.7, respectively. Pearson test results showed no significant correlation between PWC and WAI in different age groups (r=0.3 and P>0.05). Multiple linear regression analysis showed that the variables of age and diagnosed diseases were the most effective factors of WAI (β=0.18 and P>0.05). Pearson test revealed a significant correlation between the number of diagnosed diseases and PWC index in age groups of 40-49 years. Average WAI in this research, like other studies on similar jobs is in the acceptable level of >36. Work ability index and PWC index in different age groups did not show a significant correlation and this suggests that there are essential discrepancies in work ability evaluations made by each index and it is not possible to predict PWC index using WAI values. Given the PWC results and the level of nursing staff's activity (low, medium) the WAI is a suitable instrument to establish the professionals' abilities. This study revealed that 27.6% of individuals were subject to medium-low work ability risk (WAI<37), which was 1.8 times that of Finland's professional health Institute, which could be caused by shift working and increased working hours.

Is health, measured by work ability index, affected by 12-hour rotating shift schedules?

PubMed

Yong, Mei; Nasterlack, Michael; Pluto, Rolf-Peter; Elmerich, Kathrin; Karl, Dorothee; Knauth, Peter

2010-07-01

Two forms of continuously forward rotating 12-h shift schedules exist at BASF's Ludwigshafen site. These shift schedules were compared with a daytime working system to investigate potential differential effects on employee's health status assessed with the Work Ability Index (WAI). In the 3 x 12 system, a 12-h day shift is followed 24 h later by a 12-h night shift, and after a day off the employee returns to the day shift. The 4 x 12 schedule follows the same pattern except that there are 2 days off between the night and next day shift. A total of 924 participants (278 3 x 12 and 321 4 x 12 shiftworkers and 325 day workers) were recruited. A self-administered questionnaire was used to obtain information about shiftwork schedule, demographic characteristics, and lifestyle and social factors, and the WAI was applied. The outcomes of interest were the WAI sum score and its seven dimensions. In examining the relationship with the WAI categories, a Proportional Odds Model (POM) was used to identify the potential determinants. Logistic regression models were used to estimate the impact of age on single dimensions of WAI after adjustment for potential confounding factors. Increasing age and obesity (BMI > or = 30) were the only significant determinants of poorer WAI. Although a positive association was found linking the second WAI dimension (work ability in relation to job demands) with age, an inverse association was demonstrated consistently between age and the third and fourth WAI dimensions, i.e., number of diagnosed diseases and estimated work impairment due to disease, after adjustment for potential confounders. The age-dependency was moderate overall, but seemed to be stronger among shift- than day workers, although this difference did not reach statistical significance. There was no significant differential impact of the working time systems on the WAI sum score or on the individual WAI dimensions. Thus, there is no indication of an excessive adverse health impact of these shift schedules compared to day work, to the extent that health can be measured by the WAI.

Work ability index (WAI) and its association with psychosocial factors in one of the petrochemical industries in Iran.

PubMed

Mazloumi, Adel; Rostamabadi, Akbar; Nasl Saraji, Gabraeil; Rahimi Foroushani, Abbas

2012-01-01

In recent decades, work ability index (WAI) has been a common practical tool to measure individuals' work ability in many European, Asian and South American countries. However, there is no study concerning work ability in Iran. The aim of this study was to determine the work ability index in an Iranian petrochemical job setting and to examine its relationship with psychosocial factors. A cross-sectional study was conducted among 420 male workers in various occupations. Work ability was evaluated using the WAI questionnaire developed by FIOH; the Job content questionnaire (JCQ) was used to assess psychosocial factors. The mean WAI score was 39.1 (SD=5.7) among workers in the studied petrochemical industry. Multiple linear regression analysis revealed a significant association between mean WAI score and age, job tenure, educational level, rest and sleep status and vocational education. Moreover, the results showed that skill discretion, coworker support and supervisor support were positively associated with the mean WAI score. On the other hand, it was inversely associated with job demands, job strain and job insecurity. This study was the first research to determine WAI in an important industry in Iran. Overall, work ability was in the "Good" category among the workers in the studied field. On the basis of the WAI guidelines, this level should be maintained and promoted to excellent level by providing supportive countermeasures. The WAI score was significantly associated with psychosocial factors. The results showed that even in heavy physical work, factors such as job insecurity, skill discretion, job strain and social support play an important role in maintaining work ability. A positive combination of "psychosocial characteristics" of the job with "individual resources" can promote work ability in such occupations.

Help Is on the WAIS.

ERIC Educational Resources Information Center

Lukanuski, Mary

1992-01-01

Describes the development of the WAIS (Wide Area Information Servers) protocol, a system that allows users access to personal, corporate, and commercial electronic information from one interface. The availability of WAIS on the Internet and the reactions of users are addressed. Several problems are considered, including funding, hardware…

Multidimensional Relationships in the WAIS-R Subscales and Demographic Variables.

ERIC Educational Resources Information Center

Chastain, Robert L.; Joe, George W.

This study attempts to integrate and extend previous research by multivariate investigation to determine multidimensional relationships among both the Wechsler Adult Intelligence Scale-Revised (WAIS-R) subscales and the demographic variables for the 1981 WAIS-R standardization sample. Canonical correlation with orthogonal rotation of composite…

Snow Accumulation Variability Over the West Antarctic Ice Sheet Since 1900: A Comparison of Ice Core Records With ERA-20C Reanalysis

NASA Astrophysics Data System (ADS)

Wang, Yetang; Thomas, Elizabeth R.; Hou, Shugui; Huai, Baojuan; Wu, Shuangye; Sun, Weijun; Qi, Shanzhong; Ding, Minghu; Zhang, Yulun

2017-11-01

This study uses a set of 37 firn core records over the West Antarctic Ice Sheet (WAIS) to test the performance of the twentieth century from the European Centre for Medium-Range Weather Forecasts (ERA-20C) reanalysis for snow accumulation and quantify temporal variability in snow accumulation since 1900. The firn cores are allocated to four geographical areas demarcated by drainage divides (i.e., Antarctic Peninsula (AP), western WAIS, central WAIS, and eastern WAIS) to calculate stacked records of regional snow accumulation. Our results show that the interannual variability in ERA-20C precipitation minus evaporation (P - E) agrees well with the corresponding ice core snow accumulation composites in each of the four geographical regions, suggesting its skill for simulating snow accumulation changes before the modern satellite era (pre-1979). Snow accumulation experiences significantly positive trends for the AP and eastern WAIS, a negative trend for the western WAIS, and no significant trend for the central WAIS from 1900 to 2010. The contrasting trends are associated with changes in the large-scale moisture transport driven by a deepening of the low-pressure systems and anomalies of sea ice in the Amundsen Sea Low region.

Test Review: Advanced Clinical Solutions for WAIS-IV and WMS-IV

ERIC Educational Resources Information Center

Chu, Yiting; Lai, Mark H. C.; Xu, Yining; Zhou, Yuanyuan

2012-01-01

The authors review the "Advanced Clinical Solutions for WAIS-IV and WMS-IV". The "Advanced Clinical Solutions (ACS) for the Wechsler Adult Intelligence Scale-Fourth Edition" (WAIS-IV; Wechsler, 2008) and the "Wechsler Memory Scale-Fourth Edition" (WMS-IV; Wechsler, 2009) was published by Pearson in 2009. It is a…

Independent examination of the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV): what does the WAIS-IV measure?

PubMed

Benson, Nicholas; Hulac, David M; Kranzler, John H

2010-03-01

Published empirical evidence for the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) does not address some essential questions pertaining to the applied practice of intellectual assessment. In this study, the structure and cross-age invariance of the latest WAIS-IV revision were examined to (a) elucidate the nature of the constructs measured and (b) determine whether the same constructs are measured across ages. Results suggest that a Cattell-Horn-Carroll (CHC)-inspired structure provides a better description of test performance than the published scoring structure does. Broad CHC abilities measured by the WAIS-IV include crystallized ability (Gc), fluid reasoning (Gf), visual processing (Gv), short-term memory (Gsm), and processing speed (Gs), although some of these abilities are measured more comprehensively than are others. Additionally, the WAIS-IV provides a measure of quantitative reasoning (QR). Results also suggest a lack of cross-age invariance resulting from age-related differences in factor loadings. Formulas for calculating CHC indexes and suggestions for interpretation are provided. PsycINFO Database Record (c) 2010 APA, all rights reserved.

The Work Ability Index as a screening tool to identify the need for rehabilitation: longitudinal findings from the Second German Sociomedical Panel of Employees.

PubMed

Bethge, Matthias; Radoschewski, Friedrich Michael; Gutenbrunner, Christoph

2012-11-01

To evaluate the predictive value of the Work Ability Index (WAI) for different indicators of the need for rehabilitation at 1-year follow-up. Cohort study. Data were obtained from the Second German Sociomedical Panel of Employees, a large-scale cohort study with postal surveys in 2009 and 2010. A total of 457 women and 579 men were included. Confirmatory factor analysis confirmed the one-dimensionality of the WAI. Regression analyses showed that poor and moderate baseline WAI scores were associated with lower health-related quality of life and more frequent use of primary healthcare 1 year later. Subjects with poor baseline work ability had 4.6 times higher odds of unemployment and 12.2 times higher odds of prolonged sick leave than the reference group with good or excellent baseline work ability. Moreover, the odds of subjectively perceived need for rehabilitation, intention to request rehabilitation and actual use of rehabilitation services were 9.7, 5.7 and 3 times higher in the poor baseline WAI group and 5.5, 4 and 1.8 times higher in the moderate baseline WAI group, respectively. A WAI score ≤ 37 was identified as the optimal cut-off to predict the need for rehabilitation. The WAI is a valid screening tool for identifying the need for rehabilitation.

WAIS-IV and Clinical Validation of the Four- and Five-Factor Interpretative Approaches

ERIC Educational Resources Information Center

Weiss, Lawrence G.; Keith, Timothy Z.; Zhu, Jianjun; Chen, Hsinyi

2013-01-01

The fourth edition of the Wechsler Adult Intelligence Scale (WAIS-IV) is a revised and substantially updated version of its predecessor. The purposes of this research were to determine the constructs measured by the test and the consistency of measurement across large normative and clinical samples. Competing higher order WAIS-IV four- and…

Similarity of WISC-R and WAIS-R Scores at Age 16.

ERIC Educational Resources Information Center

Sandoval, Jonathan; And Others

1988-01-01

Examined similarity of scores of 30 learning disabled students (aged 16 and 17) on the Wechsler Intelligence Scale for Children-Revised (WISC-R) and the Wechsler Adult Intelligence Scale-Revised (WAIS-R). Results documented similarity between WISC-R and WAIS-R for 16 year-olds who were learning disabled and had average intellectual ability.…

Are chronotype, social jetlag and sleep duration associated with health measured by Work Ability Index?

PubMed

Yong, Mei; Fischer, Dorothee; Germann, Christina; Lang, Stefan; Vetter, Céline; Oberlinner, Christoph

The present study investigates the impact of chronotype, social jetlag and sleep duration on self-perceived health, measured by Work Ability Index (WAI), within an industrial setting. Between 2011 and 2013, 2474 day and shift workers participated in a health check offered by an occupational health promotion program and filled out the Munich ChronoType Questionnaire (adapted to the rotational 12-h schedule for shift workers) and the WAI. We computed sleep duration on work and free days, chronotype, and social jetlag. We used linear regression models to examine chronotype, sleep duration and social jetlag for association with the WAI sum score, and proportional odds models to estimate the combined effect of social jetlag and sleep duration. Participants reported an average daily sleep duration of 7.35 h (SD: 1.2 h), had an average chronotype of 3:08 a.m. (SD: 1 h), and the average social jetlag corresponded to 1.96 h (SD: 2.05 h). Increasing social jetlag and shorter sleep duration were independently associated with a decreasing WAI, while chronotype per se was not associated with WAI. Short sleep duration combined with high social jetlag significantly increased the risk of poor WAI (OR = 1.36; 95% CI: 1.09-1.72), while long sleep duration and high social jetlag were not associated with poor WAI (OR = 1.09; 95% CI: 0.88-1.35). Our results add to a growing body of literature, suggesting that circadian misalignment, but not chronotype per se, may be critical for health. Our results indicate that longer sleep may override the adverse effects of social jetlag on WAI.

Sex and Race Bias in the WAIS-R: A Content and Empirical Analysis.

ERIC Educational Resources Information Center

Wrobel, Thomas A.; Howells, Nancy R.

To examine the issue of item bias within the context of the revised Wechsler Adult Intelligence Scale (WAIS-R), judgments as to perceived item bias were sought. Independent raters nominated 53 WAIS-R items as containing possible bias. White and non-white college students nominated items as racially or sexually biased. Whereas 10 items were judged…

WAIS-III IQs, Horn's Theory, and Generational Changes from Young Adulthood to Old Age.

ERIC Educational Resources Information Center

Kaufman, Alan S.

2001-01-01

Examined age changes in intellectual ability in the range from 16 to 89 years through 2 studies that involved IQs on the Wechsler Adult Intelligence Scale III (WAIS-III). Results are interpreted in the context of the fluid-crystallized intelligence theory of J. Horn. Studies used WAIS-III standardization data for 2,450 adults and longitudinal data…

Comparison of the WAIS-III and WISC-IV in 16-Year-Old Special Education Students

ERIC Educational Resources Information Center

Gordon, Shirley; Duff, Simon; Davidson, Terry; Whitaker, Simon

2010-01-01

Background: Previous research with earlier versions of the WISC and WAIS has demonstrated that when administered to people who have intellectual disabilities, the WAIS produced higher IQ scores than the WISC. The aim of this study was to examine whether these differences still exist. A comparison of the Wechsler Adult Intelligence Scale-Third…

The rapid disintegration of projections: the West Antarctic Ice Sheet and the intergovernmental panel on climate change.

PubMed

O'Reilly, Jessica; Oreskes, Naomi; Oppenheimer, Michael

2012-10-01

How and why did the scientific consensus about sea level rise due to the disintegration of the West Antarctic Ice Sheet (WAIS), expressed in the third Intergovernmental Panel on Climate Change (IPCC) assessment, disintegrate on the road to the fourth? Using ethnographic interviews and analysis of IPCC documents, we trace the abrupt disintegration of the WAIS consensus. First, we provide a brief historical overview of scientific assessments of the WAIS. Second, we provide a detailed case study of the decision not to provide a WAIS prediction in the Fourth Assessment Report. Third, we discuss the implications of this outcome for the general issue of scientists and policymakers working in assessment organizations to make projections. IPCC authors were less certain about potential WAIS futures than in previous assessment reports in part because of new information, but also because of the outcome of cultural processes within the IPCC, including how people were selected for and worked together within their writing groups. It became too difficult for IPCC assessors to project the range of possible futures for WAIS due to shifts in scientific knowledge as well as in the institutions that facilitated the interpretations of this knowledge.

Psychological variables and Wechsler Adult Intelligence Scale-IV performance.

PubMed

Gass, Carlton S; Gutierrez, Laura

2017-01-01

The MMPI-2 and WAIS-IV are commonly used together in neuropsychological evaluations yet little is known about their interrelationships. This study explored the potential influence of psychological factors on WAIS-IV performance in a sample of 180 predominantly male veteran referrals that underwent a comprehensive neuropsychological examination in a VA Medical Center. Exclusionary criteria included failed performance validity testing and self-report distortion on the MMPI-2. A Principal Components Analysis was performed on the 15 MMPI-2 content scales, yielding three broader higher-order psychological dimensions: Internalized Emotional Dysfunction (IED), Externalized Emotional Dysfunction (EED), and Fear. Level of IED was not related to performance on the WAIS-IV Full Scale IQ or its four indexes: (Verbal Comprehension, Perceptual Reasoning, Working Memory, and Processing Speed). EED was not related to WAIS-IV performance. Level of Fear, which encompasses health preoccupations (HEA) and distorted perceptions (BIZ), was significantly related to WAIS-IV Full Scale IQ and Verbal Comprehension. These results challenge the common use of high scores on the MMPI-2 IED measures (chiefly depression and anxiety) to explain deficient WAIS-IV performance. In addition, they provide impetus for further investigation of the relation between verbal intelligence and Fear.

Structural validity of the Dutch-language version of the WAIS-III in a psychiatric sample.

PubMed

van der Heijden, Paul; van den Bos, Pancras; Mol, Bart; Kessels, Roy P C

2013-01-01

The Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV; Wechsler, 2008 ) no longer provides the "traditional" Verbal IQ and Performance IQ deviation scores. In the current study, we investigated the structural validity of these scores in the scale's predecessor, the WAIS-Third Edition (WAIS-III; Wechsler, 1997c ), which is still widely used in clinical practice, especially outside the United States. Confirmative (CFA) and exploratory factor analyses (EFA) were performed on WAIS-III data from a Dutch sample of 247 psychiatric patients. Four competing models were tested in the CFA on 11 subtests. The model that fit the data best was a model in which subtests loaded on the four factor indexes (i.e., 3 Verbal Comprehension subtests, 3 Perceptual Organization subtests, 3 Working Memory subtests, and 2 Processing Speed subtests) as proposed by the manual (Wechsler, 1997b ). In the EFA on 13 subtests with four factors extracted, all subtests were found to load on the factors in accordance with the WAIS-III test manual. However, Picture Arrangement, Arithmetic, and Picture Completion showed only moderate loadings on the proposed factors. Implications for clinical practice are discussed.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moore, Bria M.; Brady, Samuel L., E-mail: samuel.brady@stjude.org; Kaufman, Robert A.

Purpose: To investigate the correlation of size-specific dose estimate (SSDE) with absorbed organ dose, and to develop a simple methodology for estimating patient organ dose in a pediatric population (5–55 kg). Methods: Four physical anthropomorphic phantoms representing a range of pediatric body habitus were scanned with metal oxide semiconductor field effect transistor (MOSFET) dosimeters placed at 23 organ locations to determine absolute organ dose. Phantom absolute organ dose was divided by phantom SSDE to determine correlation between organ dose and SSDE. Organ dose correlation factors (CF{sub SSDE}{sup organ}) were then multiplied by patient-specific SSDE to estimate patient organ dose. Themore » CF{sub SSDE}{sup organ} were used to retrospectively estimate individual organ doses from 352 chest and 241 abdominopelvic pediatric CT examinations, where mean patient weight was 22 kg ± 15 (range 5–55 kg), and mean patient age was 6 yrs ± 5 (range 4 months to 23 yrs). Patient organ dose estimates were compared to published pediatric Monte Carlo study results. Results: Phantom effective diameters were matched with patient population effective diameters to within 4 cm; thus, showing appropriate scalability of the phantoms across the entire pediatric population in this study. IndividualCF{sub SSDE}{sup organ} were determined for a total of 23 organs in the chest and abdominopelvic region across nine weight subcategories. For organs fully covered by the scan volume, correlation in the chest (average 1.1; range 0.7–1.4) and abdominopelvic region (average 0.9; range 0.7–1.3) was near unity. For organ/tissue that extended beyond the scan volume (i.e., skin, bone marrow, and bone surface), correlation was determined to be poor (average 0.3; range: 0.1–0.4) for both the chest and abdominopelvic regions, respectively. A means to estimate patient organ dose was demonstrated. Calculated patient organ dose, using patient SSDE and CF{sub SSDE}{sup organ}, was compared to previously published pediatric patient doses that accounted for patient size in their dose calculation, and was found to agree in the chest to better than an average of 5% (27.6/26.2) and in the abdominopelvic region to better than 2% (73.4/75.0). Conclusions: For organs fully covered within the scan volume, the average correlation of SSDE and organ absolute dose was found to be better than ±10%. In addition, this study provides a complete list of organ dose correlation factors (CF{sub SSDE}{sup organ}) for the chest and abdominopelvic regions, and describes a simple methodology to estimate individual pediatric patient organ dose based on patient SSDE.« less

Speed of Information Processing and Individual Differences in Intelligence.

DTIC Science & Technology

1986-06-01

years of age. As criteria, the students were given the Vocabulary and Block Design subtests of the Wechsler Adult Intelligence Scale --Revised (WAIS-R... Wechsler Adult Intelligence Scale (WAIS) and inspection time (Nettelbeck & Lally, 1976), most subsequent investigations found a less spectacular, but...Design sdbtests of the Wechsler Adult Intelligence Scale , Revised (WAIS-R) and the Cognitive Laterality Battery (Gordon, 1983). Visual Processing Tasks

Safety of minimally invasive radical prostatectomy in patients with prior abdominopelvic or inguinal surgery.

PubMed

Ball, Mark W; Reese, Adam C; Mettee, Lynda Z; Pavlovich, Christian P

2015-02-01

Despite the widespread use of minimally invasive radical prostatectomy (MIRP), there remain concerns regarding its safety in patients with a history of prior abdominopelvic or inguinal surgery. A prospective database of 1165 MIRP procedures performed by a single surgeon at a high-volume tertiary care center from 2001 to 2013 was analyzed. After an initial period of transperitoneal MIRP (TP), an extraperitoneal (EP) approach was used preferentially beginning in 2005 (for both laparoscopic and robotic cases), and robotics were used preferentially beginning in 2010. Overall perioperative complications, major complications (Clavien-Dindo III or IV), and abdominal complications (e.g., ileus, bowel/organ injury, or vascular injury) were compared for patients with and without a prior surgical history. Uni- and multivariate logistic regression were used to control the impact of robotics, approach, operative time, estimated blood loss, case number, prostate weight, and primary Gleason on complications. Three hundred patients undergoing MIRP had prior abdominopelvic or inguinal surgery (25.8%). Of these, 102 (34%) underwent TP and 198 (66%) EP MIRP. Robotics was used in 286 cases (24.6%) and pure laparoscopy in 879 (75.4%). Complications occurred in 111 patients (9.5%) from the total cohort, with major complications in 32 (2.75%) and abdominal complications in 19 (1.63%). Prior surgery was not associated with overall, major, or abdominal complications. Of the controlling factors, only increasing operative time was associated with postoperative abdominal complications (most of which were ileus) on multivariate analysis. In this large single-surgeon series where both EP and TP approaches to MIRP are utilized, prior abdominopelvic or inguinal surgery was not associated with an increased risk of perioperative complications.

Development and Validation of the Suprathreshold Stochastic Resonance-Based Image Processing Method for the Detection of Abdomino-pelvic Tumor on PET/CT Scans.

PubMed

Saroha, Kartik; Pandey, Anil Kumar; Sharma, Param Dev; Behera, Abhishek; Patel, Chetan; Bal, Chandrashekhar; Kumar, Rakesh

2017-01-01

The detection of abdomino-pelvic tumors embedded in or nearby radioactive urine containing 18F-FDG activity is a challenging task on PET/CT scan. In this study, we propose and validate the suprathreshold stochastic resonance-based image processing method for the detection of these tumors. The method consists of the addition of noise to the input image, and then thresholding it that creates one frame of intermediate image. One hundred such frames were generated and averaged to get the final image. The method was implemented using MATLAB R2013b on a personal computer. Noisy image was generated using random Poisson variates corresponding to each pixel of the input image. In order to verify the method, 30 sets of pre-diuretic and its corresponding post-diuretic PET/CT scan images (25 tumor images and 5 control images with no tumor) were included. For each sets of pre-diuretic image (input image), 26 images (at threshold values equal to mean counts multiplied by a constant factor ranging from 1.0 to 2.6 with increment step of 0.1) were created and visually inspected, and the image that most closely matched with the gold standard (corresponding post-diuretic image) was selected as the final output image. These images were further evaluated by two nuclear medicine physicians. In 22 out of 25 images, tumor was successfully detected. In five control images, no false positives were reported. Thus, the empirical probability of detection of abdomino-pelvic tumors evaluates to 0.88. The proposed method was able to detect abdomino-pelvic tumors on pre-diuretic PET/CT scan with a high probability of success and no false positives.

Neuropsychological Profiles on the WAIS-IV of Adults With ADHD.

PubMed

Theiling, Johanna; Petermann, Franz

2016-11-01

The aim of the study was to investigate the pattern of neuropsychological profiles on the Wechsler Adult Intelligence Scale-IV (WAIS-IV) for adults With ADHD relative to randomly matched controls and to assess overall intellectual ability discrepancies of the Full Scale Intelligence Quotient (FSIQ) and the General Ability Index (GAI). In all, 116 adults With ADHD and 116 controls between 16 and 71 years were assessed. Relative to controls, adults With ADHD show significant decrements in subtests with working memory and processing speed demands with moderate to large effect sizes and a higher GAI in comparison with the FSIQ. This suggests first that deficits identified with previous WAIS versions are robust in adults With ADHD and remain deficient when assessed with the WAIS-IV; second that the WAIS-IV reliably differentiates between patients and controls; and third that a reduction of the FSIQ is most likely due to a decrement in working memory and processing speed abilities. The findings have essential implications for the diagnostic process. © The Author(s) 2014.

January 2016 extensive summer melt in West Antarctica favoured by strong El Niño

DOE PAGES

Nicolas, Julien P.; Vogelmann, Andrew M.; Scott, Ryan C.; ...

2017-06-15

Over the past two decades the primary driver of mass loss from the West Antarctic Ice Sheet (WAIS) has been warm ocean water underneath coastal ice shelves, not a warmer atmosphere. Yet, surface melt occurs sporadically over low-lying areas of the WAIS and is not fully understood. Here we report on an episode of extensive and prolonged surface melting observed in the Ross Sea sector of the WAIS in January 2016. A comprehensive cloud and radiation experiment at the WAIS ice divide, downwind of the melt region, provided detailed insight into the physical processes at play during the event. Themore » unusual extent and duration of the melting are linked to strong and sustained advection of warm marine air toward the area, likely favoured by the concurrent strong El Niño event. Finally, the increase in the number of extreme El Niño events projected for the twenty-first century could expose the WAIS to more frequent major melt events.« less

Influence of West Antarctic Ice Sheet collapse on Antarctic surface climate

NASA Astrophysics Data System (ADS)

Steig, Eric J.; Huybers, Kathleen; Singh, Hansi A.; Steiger, Nathan J.; Ding, Qinghua; Frierson, Dargan M. W.; Popp, Trevor; White, James W. C.

2015-06-01

Climate model simulations are used to examine the impact of a collapse of the West Antarctic Ice Sheet (WAIS) on the surface climate of Antarctica. The lowered topography following WAIS collapse produces anomalous cyclonic circulation with increased flow of warm, maritime air toward the South Pole and cold-air advection from the East Antarctic plateau toward the Ross Sea and Marie Byrd Land, West Antarctica. Relative to the background climate, areas in East Antarctica that are adjacent to the WAIS warm, while substantial cooling (several °C) occurs over parts of West Antarctica. Anomalously low isotope-paleotemperature values at Mount Moulton, West Antarctica, compared with ice core records in East Antarctica, are consistent with collapse of the WAIS during the last interglacial period, Marine Isotope Stage 5e. More definitive evidence might be recoverable from an ice core record at Hercules Dome, East Antarctica, which would experience significant warming and positive oxygen isotope anomalies if the WAIS collapsed.

January 2016 extensive summer melt in West Antarctica favoured by strong El Niño

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nicolas, Julien P.; Vogelmann, Andrew M.; Scott, Ryan C.

Over the past two decades the primary driver of mass loss from the West Antarctic Ice Sheet (WAIS) has been warm ocean water underneath coastal ice shelves, not a warmer atmosphere. Yet, surface melt occurs sporadically over low-lying areas of the WAIS and is not fully understood. Here we report on an episode of extensive and prolonged surface melting observed in the Ross Sea sector of the WAIS in January 2016. A comprehensive cloud and radiation experiment at the WAIS ice divide, downwind of the melt region, provided detailed insight into the physical processes at play during the event. Themore » unusual extent and duration of the melting are linked to strong and sustained advection of warm marine air toward the area, likely favoured by the concurrent strong El Niño event. Finally, the increase in the number of extreme El Niño events projected for the twenty-first century could expose the WAIS to more frequent major melt events.« less

January 2016 extensive summer melt in West Antarctica favoured by strong El Niño

NASA Astrophysics Data System (ADS)

Nicolas, Julien P.; Vogelmann, Andrew M.; Scott, Ryan C.; Wilson, Aaron B.; Cadeddu, Maria P.; Bromwich, David H.; Verlinde, Johannes; Lubin, Dan; Russell, Lynn M.; Jenkinson, Colin; Powers, Heath H.; Ryczek, Maciej; Stone, Gregory; Wille, Jonathan D.

2017-06-01

Over the past two decades the primary driver of mass loss from the West Antarctic Ice Sheet (WAIS) has been warm ocean water underneath coastal ice shelves, not a warmer atmosphere. Yet, surface melt occurs sporadically over low-lying areas of the WAIS and is not fully understood. Here we report on an episode of extensive and prolonged surface melting observed in the Ross Sea sector of the WAIS in January 2016. A comprehensive cloud and radiation experiment at the WAIS ice divide, downwind of the melt region, provided detailed insight into the physical processes at play during the event. The unusual extent and duration of the melting are linked to strong and sustained advection of warm marine air toward the area, likely favoured by the concurrent strong El Niño event. The increase in the number of extreme El Niño events projected for the twenty-first century could expose the WAIS to more frequent major melt events.

Intelligence is in the eye of the beholder: investigating repeated IQ measurements in forensic psychiatry.

PubMed

Habets, Petra; Jeandarme, Inge; Uzieblo, Kasia; Oei, Karel; Bogaerts, Stefan

2015-05-01

A stable assessment of cognition is of paramount importance for forensic psychiatric patients (FPP). The purpose of this study was to compare repeated measures of IQ scores in FPPs with and without intellectual disability. Repeated measurements of IQ scores in FPPs (n = 176) were collected. Differences between tests were computed, and each IQ score was categorized. Additionally, t-tests and regression analyses were performed. Differences of 10 points or more were found in 66% of the cases comparing WAIS-III with RAVEN scores. Fisher's exact test revealed differences between two WAIS-III scores and the WAIS categories. The WAIS-III did not predict other IQs (WAIS or RAVEN) in participants with intellectual disability. This study showed that stability or interchangeability of scores is lacking, especially in individuals with intellectual disability. Caution in interpreting IQ scores is therefore recommended, and the use of the unitary concept of IQ should be discouraged. © 2014 John Wiley & Sons Ltd.

Investigation of the factor structure of the Wechsler Adult Intelligence Scale--Fourth Edition (WAIS-IV): exploratory and higher order factor analyses.

PubMed

Canivez, Gary L; Watkins, Marley W

2010-12-01

The present study examined the factor structure of the Wechsler Adult Intelligence Scale--Fourth Edition (WAIS-IV; D. Wechsler, 2008a) standardization sample using exploratory factor analysis, multiple factor extraction criteria, and higher order exploratory factor analysis (J. Schmid & J. M. Leiman, 1957) not included in the WAIS-IV Technical and Interpretation Manual (D. Wechsler, 2008b). Results indicated that the WAIS-IV subtests were properly associated with the theoretically proposed first-order factors, but all but one factor-extraction criterion recommended extraction of one or two factors. Hierarchical exploratory analyses with the Schmid and Leiman procedure found that the second-order g factor accounted for large portions of total and common variance, whereas the four first-order factors accounted for small portions of total and common variance. It was concluded that the WAIS-IV provides strong measurement of general intelligence, and clinical interpretation should be primarily at that level.

The Utility of Seven-Subtest Short Forms of the Wechsler Adult Intelligence Scale-III in Young Adults

ERIC Educational Resources Information Center

Tam, Wai-Cheong Carl

2004-01-01

Along with ongoing research on the WAIS-R, short forms of the WAIS-III have attracted much attention. However, few studies of WAIS-III short forms are based on normal samples or on the validation of estimated indexes. This study examined the utility of two seven-subtest short forms in 81 healthy young adults in Taiwan with the administration of…

Stanford-Binet and WAIS IQ Differences and Their Implications for Adults with Intellectual Disability (aka Mental Retardation)

ERIC Educational Resources Information Center

Silverman, Wayne; Miezejeski, Charles; Ryan, Robert; Zigman, Warren; Krinsky-McHale, Sharon; Urv, Tiina

2010-01-01

Stanford-Binet and Wechsler Adult Intelligence Scale (WAIS) IQs were compared for a group of 74 adults with intellectual disability (ID). In every case, WAIS Full Scale IQ was higher than the Stanford-Binet Composite IQ, with a mean difference of 16.7 points. These differences did not appear to be due to the lower minimum possible score for the…

Measuring Working Memory With Digit Span and the Letter-Number Sequencing Subtests From the WAIS-IV: Too Low Manipulation Load and Risk for Underestimating Modality Effects.

PubMed

Egeland, Jens

2015-01-01

The Wechsler Adult Intelligence Scale (WAIS) is one of the most frequently used tests among psychologists. In the fourth edition of the test (WAIS-IV), the subtests Digit Span and Letter-Number Sequencing are expanded for better measurement of working memory (WM). However, it is not clear whether the new extended tasks contribute sufficient complexity to be sensitive measures of manipulation WM, nor do we know to what degree WM capacity differs between the visual and the auditory modality because the WAIS-IV only tests the auditory modality. Performance by a mixed sample of 226 patients referred for neuropsychological examination on the Digit Span and Letter-Number Sequencing subtests from the WAIS-IV and on Spatial Span from the Wechsler Memory Scale-Third Edition was analyzed in two confirmatory factor analyses to investigate whether a unitary WM model or divisions based on modality or level/complexity best fit the data. The modality model showed the best fit when analyzing summed scores for each task as well as scores for the longest span. The clinician is advised to apply tests with higher manipulation load and to consider testing visual span as well before drawing conclusions about impaired WM from the WAIS-IV.

Personality traits, interpersonal problems and therapeutic alliance in early schizophrenia spectrum disorders.

PubMed

Johansen, Ragnhild; Melle, Ingrid; Iversen, Valentina Cabral; Hestad, Knut

2013-11-01

The quality of the therapeutic alliance is associated with engagement in- and thus important to the outcome of- treatment in schizophrenia. In non-psychotic disorders, general personality traits and individual patterns of interpersonal problems have been linked to the formation and quality of the therapeutic alliance. The role of these factors in relation to therapeutic alliance has not previously been explored in schizophrenia spectrum disorders. To investigate associations between personality traits, interpersonal problems and the quality of the therapeutic alliance in early schizophrenia spectrum disorders. Demographic and clinical characteristics including Positive and Negative Syndrome Scale (PANSS) scores were assessed in 42 patients. Personality traits and interpersonal problems were assessed with the NEO Five factor Inventory (NEO-FFI) and the circumplex model of the Inventory of Interpersonal Problems (IIP-64C). Therapeutic alliance was measured with the Working Alliance Inventory - short form (WAI-S). Patient WAI-S scores were predicted by IIP-64C Submissive/Hostile interpersonal problems, age and PANSS excitative symptoms. Therapist WAI-S scores were predicted by NEO-FFI Agreeableness and the PANSS insight item. Core traits of personality and dimensions of interpersonal problems are associated with both patients' and therapists' perceptions of the quality of the working alliance. Copyright © 2013 Elsevier Inc. All rights reserved.

The Global and Local Climatic Response to the Collapse of the West Antarctic Ice Sheet

NASA Astrophysics Data System (ADS)

Huybers, K. M.; Singh, H.; Steiger, N. J.; Frierson, D. M.; Steig, E. J.; Bitz, C. M.

2014-12-01

Glaciologists have suggested that a relatively small external forcing may compromise the stability of the West Antarctic Ice Sheet (WAIS). Further, there is compelling physical evidence that the WAIS has collapsed in the past, at times when the mean global temperature was only a few degrees warmer than it is today. In addition to a rapid increase in global sea level, the collapse of the WAIS could also affect the global circulation of the atmosphere. Ice sheets are some of the largest topographic features on Earth, causing large regional anomalies in albedo and radiative balance. Our work uses idealized aquaplanet models in tandem with a fully coupled ocean/atmosphere/sea-ice model (CCSM4) to compare the atmospheric, radiative, and oceanic response to a complete loss of the WAIS. Initial findings indicate that the loss of the WAIS leads to a weakening and equator-ward shift of the zonal winds, a development of strong zonal asymmetries in the meridional wind, and a northward migration of the Intertropical Convergence Zone. We aim to characterize how the local and global climate is affected by the presence of the WAIS, and how changes in the distribution of Southern Hemisphere ice may be represented in the proxy record.

[Study on relationship between fatigue and work ability in chemistry workers].

PubMed

Wu, Si-Ying; Wang, Mian-Zhen; Wang, Zhi-Ming; Lan, Ya-Jia

2005-01-01

Explore the relationship between fatigue and work ability in 976 chemistry workers. A test of fatigue and work ability was carried out with fatigue scale and work ability index (WAI) for 976 workers, other influence factors of the work ability (such as work environment, labor load, job factors) were investigated with questionnaire. (1) The frequency of fatigue of the unmarried workers was significantly lower than that of the married workers and other marital status workers, while the score of WAI of the unmarried was significantly higher than that of those( P < 0.05); (2) the frequency of fatigue of the mental workers was significantly lower than that of the mixed physical and mental workers, while the score of WAI of the mental workers was significantly higher than that of physical workers and mixed physical and mental workers ( P < 0.05); (3) compared with the workers free of fatigue, the other workers had lower WAI scores; (4) the fatigue score correlated negatively to the WAI score (r = -0.499, P < 0.01); (5) Cumulative odds model analysis showed that after controlling the other risk factors, fatigue was an important risk factor of work ability (OR = 4.005). Fatigue has affected work ability in chemistry workers, the frequency of fatigue is higher, the score of WAI is lower.

Searching for a neurologic injury's Wechsler Adult Intelligence Scale-Third Edition profile.

PubMed

Gonçalves, Marta A; Moura, Octávio; Castro-Caldas, Alexandre; Simões, Mário R

2017-01-01

This study aimed to investigate the presence of a Wechsler Adult Intelligence Scale-Third Edition (WAIS-III) cognitive profile in a Portuguese neurologic injured sample. The Portuguese WAIS-III was administered to 81 mixed neurologic patients and 81 healthy matched controls selected from the Portuguese standardization sample. Although the mixed neurologic injury group performed significantly lower than the healthy controls for the majority of the WAIS-III scores (i.e., composite measures, discrepancies, and subtests), the mean scores were within the normal range and, therefore, at risk of being unobserved in a clinical evaluation. ROC curves analysis showed poor to acceptable diagnostic accuracy for the WAIS-III composite measures and subtests (Working Memory Index and Digit Span revealed the highest accuracy for discriminating between participants, respectively). Multiple regression analysis showed that both literacy and the presence of brain injury were significant predictors for all of the composite measures. In addition, multiple regression analysis also showed that literacy, age of injury onset, and years of survival predicted all seven composite measures for the mixed neurologic injured group. Despite the failure to find a WAIS-III cognitive profile for mixed neurologic patients, the results showed a significant influence of brain lesion and literacy in the performance of the WAIS-III.

Is work engagement related to work ability beyond working conditions and lifestyle factors?

PubMed

Airila, Auli; Hakanen, Jari; Punakallio, Anne; Lusa, Sirpa; Luukkonen, Ritva

2012-11-01

To examine the associations of age, lifestyle and work-related factors, and particularly work engagement with the work ability index (WAI) and its sub-dimensions. Step-wise regression analysis with a sample of Finnish firefighters (n = 403) was used. The outcome variables were the WAI and its six sub-dimensions. The independent variables consisted of age, lifestyle variables (alcohol consumption, BMI, smoking, physical exercise, and sleep problems), working conditions (job demands, physical workload, supervisory relations, and task resources), and work engagement. The outcome variables and all the variables related to lifestyle, working conditions, and work engagement were measured in 2009. Work ability at baseline 10 years earlier was adjusted for in the models. Work engagement, age, physical exercise, sleep problems, and physical workload were associated with the WAI. All independent variables, except BMI and alcohol consumption, were associated with at least one sub-dimension of the WAI after controlling the baseline WAI. Lifestyle variables, working conditions, and work engagement were more strongly related to the subjective WAI sub-dimensions than to the two more objective WAI sub-dimensions. Work engagement was significantly associated with work ability even after adjusting for various factors, indicating its importance in promoting work ability. Other key factors for good work ability were frequent exercise, good sleep, non-smoking, low job demands, low physical workload, and high task resources. More specifically, this study suggests that in maintaining work ability, it is valuable not only to promote lifestyle factors or working conditions, but also to enhance employees' positive state of work engagement.

Predictive validity of the Work Ability Index and its individual items in the general population.

PubMed

Lundin, Andreas; Leijon, Ola; Vaez, Marjan; Hallgren, Mats; Torgén, Margareta

2017-06-01

This study assesses the predictive ability of the full Work Ability Index (WAI) as well as its individual items in the general population. The Work, Health and Retirement Study (WHRS) is a stratified random national sample of 25-75-year-olds living in Sweden in 2000 that received a postal questionnaire ( n = 6637, response rate = 53%). Current and subsequent sickness absence was obtained from registers. The ability of the WAI to predict long-term sickness absence (LTSA; ⩾ 90 consecutive days) during a period of four years was analysed by logistic regression, from which the Area Under the Receiver Operating Characteristic curve (AUC) was computed. There were 313 incident LTSA cases among 1786 employed individuals. The full WAI had acceptable ability to predict LTSA during the 4-year follow-up (AUC = 0.79; 95% CI 0.76 to 0.82). Individual items were less stable in their predictive ability. However, three of the individual items: current work ability compared with lifetime best, estimated work impairment due to diseases, and number of diagnosed current diseases, exceeded AUC > 0.70. Excluding the WAI item on number of days on sickness absence did not result in an inferior predictive ability of the WAI. The full WAI has acceptable predictive validity, and is superior to its individual items. For public health surveys, three items may be suitable proxies of the full WAI; current work ability compared with lifetime best, estimated work impairment due to diseases, and number of current diseases diagnosed by a physician.

Work Ability Index as tool to identify workers at risk of premature work exit.

PubMed

Roelen, Corné A M; Heymans, Martijn W; Twisk, Jos W R; van der Klink, Jac J L; Groothoff, Johan W; van Rhenen, Willem

2014-12-01

To investigate the Work Ability Index (WAI) as tool for identifying workers at risk of premature work exit in terms of disability pension, unemployment, or early retirement. Prospective cohort study of 11,537 male construction workers (mean age 45.5 years), who completed the WAI at baseline and reported their work status (employed, unemployed, disability pension, or retired) after mean 2.3 years of follow-up. Associations between WAI scores and work status were investigated by multinomial logistic regression analysis. The ability of the WAI to discriminate between workers at high and low risk of premature work exit was analyzed by the area (AUC) under the receiver operating characteristic curve. 9,530 (83 %) construction workers had complete data for analysis. At follow-up, 336 (4 %) workers reported disability pension, 125 (1 %) unemployment, and 255 (3 %) retirement. WAI scores were prospectively associated with the risk of disability pension at follow-up, but not with the risk of unemployment and early retirement. The WAI showed fair discrimination to identify workers at risk of disability pension [AUC = 0.74; 95 % confidence interval (CI) 0.70-0.77]. The discriminative ability decreased with age from AUC = 0.78 in workers aged 30-39 years to AUC = 0.69 in workers ≥50 years of age. Discrimination failed for unemployment (AUC = 0.51; 95 % CI 0.47-0.55) and early retirement (AUC = 0.58; 95 % CI 0.53-0.61). The WAI can be used to identify construction workers <50 years of age at increased risk of disability pension and invite them for preventive interventions.

The Role of the Working Alliance in Treatment for Alcohol Problems

PubMed Central

2015-01-01

Little research has been done on the role of the therapeutic working alliance in treatment for alcohol problems. This longitudinal study’s objectives were (a) to identify predictors of working alliance and (b) to investigate whether client and/or therapist reports of the working alliance predicted posttreatment motivation and then later treatment outcome. Client and therapist perceptions of the working alliance were assessed after the first treatment session using a short form of the Working Alliance Inventory (WAI) among 173 clients taking part in the United Kingdom Alcohol Treatment Trial (UKATT) and randomized to motivational enhancement therapy (MET) or social behavior and network therapy (SBNT) with complete data on all measures of interest. Structural equation models were fitted to identify predictors of WAI scores and investigate the relationships between WAI and measures of drinking during treatment, posttreatment motivation, and successful treatment outcome (abstinent or nonproblem drinker), and measures of drinks per drinking day and nondrinking days, assessed 9 months after the conclusion of treatment. Motivation to change drinking when treatment began was a strong predictor of client—adjusted coefficient = 2.21 (95% confidence interval [CI] [0.36, 4.06]—but not therapist WAI. Client WAI predicted successful treatment outcome—adjusted odds ratios (OR) = 1.09 (95% CI [1.02, 1.17])—and had effects on drinking during treatment, and on posttreatment motivation to change. There was evidence for effect modification by treatment, with strong associations between WAI and posttreatment motivation, and evidence of WAI prediction of treatment outcomes in the MET group, but no evidence of associations for SBNT. Therapist WAI was not strongly associated with treatment outcome (adjusted OR = 1.05; 95% CI [0.99, 1.10]). The working alliance is important to treatment outcomes for alcohol problems, with client evaluation of the alliance strongly related to motivation to change drinking throughout treatment for MET. It was also much more important than therapist-rated alliance in this study. PMID:25961147

Dating glacimarine sediments from the continental shelf in the Amundsen Sea using a multi-tool box: Implications for West Antarctic ice-sheet extent and retreat during the last glacial cycle

NASA Astrophysics Data System (ADS)

Hillenbrand, C. D.; Smith, J.; Klages, J. P.; Kuhn, G.; Maher, B.; Moreton, S.; Wacker, L.; Frederichs, T.; Wiers, S.; Jernas, P.; Anderson, J. B.; Ehrmann, W. U.; Graham, A. G. C.; Gohl, K.; Larter, R. D.

2016-02-01

Satellite data and in-situ measurements show that today considerable mass loss is occurring from the Amundsen Sea sector of the West Antarctic Ice Sheet (WAIS). The observational record only spans the past four decades, and until recently the long-term context of the current deglaciation was poorly constrained. This information is, however, crucial for understanding WAIS dynamics, evaluating the role of forcing mechanisms for ice-sheet melting, and testing and calibrating ice-sheet models that attempt to predict future WAIS behavior and its impact on global sea level. Over the past decade several multinational marine expeditions and terrestrial fieldwork campaigns have targeted the Amundsen Sea shelf and its hinterland to reconstruct the WAIS configuration during the Last Glacial Maximum (LGM) and its subsequent deglacial history. The resulting studies succeeded in shedding light on the maximum WAIS extent at the LGM and the style, pattern and speed of its retreat and thinning thereafter. Despite this progress, however, significant uncertainties and discrepancies between marine and terrestrial reconstructions remain, which may arise from difficulties in dating sediment cores from the Antarctic shelf, especially their deglacial sections. Resolving these issues is crucial for understanding the WAIS' contribution to post-LGM sea-level rise, its sensitivity to different forcing mechanisms and its future evolution. Here we present chronological constraints on WAIS advance in the Amundsen Sea and its retreat from 20 ka BP into the Holocene that were obtained by various techniques, such as 14C dating of large ( 10 mg) and small (<<1 mg) sample aliquots of calcareous microfossils, 14C dating of acid-insoluble organic matter combusted at low (300 °C) and high (800 °C) temperatures and dating of sediment cores by using geomagnetic paleointensity. We will compare the different age constraints and discuss their reliability, applicability and implications for WAIS history.

Development of a Simple Image Processing Application that Makes Abdominopelvic Tumor Visible on Positron Emission Tomography/Computed Tomography Image.

PubMed

Pandey, Anil Kumar; Saroha, Kartik; Sharma, Param Dev; Patel, Chetan; Bal, Chandrashekhar; Kumar, Rakesh

2017-01-01

In this study, we have developed a simple image processing application in MATLAB that uses suprathreshold stochastic resonance (SSR) and helps the user to visualize abdominopelvic tumor on the exported prediuretic positron emission tomography/computed tomography (PET/CT) images. A brainstorming session was conducted for requirement analysis for the program. It was decided that program should load the screen captured PET/CT images and then produces output images in a window with a slider control that should enable the user to view the best image that visualizes the tumor, if present. The program was implemented on personal computer using Microsoft Windows and MATLAB R2013b. The program has option for the user to select the input image. For the selected image, it displays output images generated using SSR in a separate window having a slider control. The slider control enables the user to view images and select one which seems to provide the best visualization of the area(s) of interest. The developed application enables the user to select, process, and view output images in the process of utilizing SSR to detect the presence of abdominopelvic tumor on prediuretic PET/CT image.

Patient- and cohort-specific dose and risk estimation for abdominopelvic CT: a study based on 100 patients

NASA Astrophysics Data System (ADS)

Tian, Xiaoyu; Li, Xiang; Segars, W. Paul; Frush, Donald P.; Samei, Ehsan

2012-03-01

The purpose of this work was twofold: (a) to estimate patient- and cohort-specific radiation dose and cancer risk index for abdominopelvic computer tomography (CT) scans; (b) to evaluate the effects of patient anatomical characteristics (size, age, and gender) and CT scanner model on dose and risk conversion coefficients. The study included 100 patient models (42 pediatric models, 58 adult models) and multi-detector array CT scanners from two commercial manufacturers (LightSpeed VCT, GE Healthcare; SOMATOM Definition Flash, Siemens Healthcare). A previously-validated Monte Carlo program was used to simulate organ dose for each patient model and each scanner, from which DLP-normalized-effective dose (k factor) and DLP-normalized-risk index values (q factor) were derived. The k factor showed exponential decrease with increasing patient size. For a given gender, q factor showed exponential decrease with both increasing patient size and patient age. The discrepancies in k and q factors across scanners were on average 8% and 15%, respectively. This study demonstrates the feasibility of estimating patient-specific organ dose and cohort-specific effective dose and risk index in abdominopelvic CT requiring only the knowledge of patient size, gender, and age.

Stanford-Binet & WAIS IQ Differences and Their Implications for Adults with Intellectual Disability (aka Mental Retardation).

PubMed

Silverman, Wayne; Miezejeski, Charles; Ryan, Robert; Zigman, Warren; Krinsky-McHale, Sharon; Urv, Tiina

2010-03-01

Stanford-Binet and Wechsler Adult Intelligence Scale (WAIS) IQs were compared for a group of 74 adults with intellectual disability (ID). In every case, WAIS Full Scale IQ was higher than the Stanford-Binet Composite IQ, with a mean difference of 16.7 points. These differences did not appear to be due to the lower minimum possible score for the Stanford-Binet. Additional comparisons with other measures suggested that the WAIS might systematically underestimate severity of intellectual impairment. Implications of these findings are discussed regarding determination of disability status, estimating prevalence of ID, assessing dementia and aging-related cognitive declines, and diagnosis of ID in forensic cases involving a possible death penalty.

Stanford-Binet & WAIS IQ Differences and Their Implications for Adults with Intellectual Disability (aka Mental Retardation)

PubMed Central

Silverman, Wayne; Miezejeski, Charles; Ryan, Robert; Zigman, Warren; Krinsky-McHale, Sharon; Urv, Tiina

2010-01-01

Stanford-Binet and Wechsler Adult Intelligence Scale (WAIS) IQs were compared for a group of 74 adults with intellectual disability (ID). In every case, WAIS Full Scale IQ was higher than the Stanford-Binet Composite IQ, with a mean difference of 16.7 points. These differences did not appear to be due to the lower minimum possible score for the Stanford-Binet. Additional comparisons with other measures suggested that the WAIS might systematically underestimate severity of intellectual impairment. Implications of these findings are discussed regarding determination of disability status, estimating prevalence of ID, assessing dementia and aging-related cognitive declines, and diagnosis of ID in forensic cases involving a possible death penalty. PMID:20401180

Prospective estimation of organ dose in CT under tube current modulation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tian, Xiaoyu, E-mail: xt3@duke.edu; Li, Xiang; Segars, W. Paul

Purpose: Computed tomography (CT) has been widely used worldwide as a tool for medical diagnosis and imaging. However, despite its significant clinical benefits, CT radiation dose at the population level has become a subject of public attention and concern. In this light, optimizing radiation dose has become a core responsibility for the CT community. As a fundamental step to manage and optimize dose, it may be beneficial to have accurate and prospective knowledge about the radiation dose for an individual patient. In this study, the authors developed a framework to prospectively estimate organ dose for chest and abdominopelvic CT examsmore » under tube current modulation (TCM). Methods: The organ dose is mainly dependent on two key factors: patient anatomy and irradiation field. A prediction process was developed to accurately model both factors. To model the anatomical diversity and complexity in the patient population, the authors used a previously developed library of computational phantoms with broad distributions of sizes, ages, and genders. A selected clinical patient, represented by a computational phantom in the study, was optimally matched with another computational phantom in the library to obtain a representation of the patient’s anatomy. To model the irradiation field, a previously validated Monte Carlo program was used to model CT scanner systems. The tube current profiles were modeled using a ray-tracing program as previously reported that theoretically emulated the variability of modulation profiles from major CT machine manufacturers Li et al., [Phys. Med. Biol. 59, 4525–4548 (2014)]. The prediction of organ dose was achieved using the following process: (1) CTDI{sub vol}-normalized-organ dose coefficients (h{sub organ}) for fixed tube current were first estimated as the prediction basis for the computational phantoms; (2) each computation phantom, regarded as a clinical patient, was optimally matched with one computational phantom in the library; (3) to account for the effect of the TCM scheme, a weighted organ-specific CTDI{sub vol} [denoted as (CTDI{sub vol}){sub organ,weighted}] was computed for each organ based on the TCM profile and the anatomy of the “matched” phantom; (4) the organ dose was predicted by multiplying the weighted organ-specific CTDI{sub vol} with the organ dose coefficients (h{sub organ}). To quantify the prediction accuracy, each predicted organ dose was compared with the corresponding organ dose simulated from the Monte Carlo program with the TCM profile explicitly modeled. Results: The predicted organ dose showed good agreements with the simulated organ dose across all organs and modulation profiles. The average percentage error in organ dose estimation was generally within 20% across all organs and modulation profiles, except for organs located in the pelvic and shoulder regions. For an average CTDI{sub vol} of a CT exam of 10 mGy, the average error at full modulation strength (α = 1) across all organs was 0.91 mGy for chest exams, and 0.82 mGy for abdominopelvic exams. Conclusions: This study developed a quantitative model to predict organ dose for clinical chest and abdominopelvic scans. Such information may aid in the design of optimized CT protocols in relation to a targeted level of image quality.« less

Therapeutic alliance in dietetic practice for weight loss: Insights from health coaching.

PubMed

Nagy, Annaliese; McMahon, Anne; Tapsell, Linda; Deane, Frank; Arenson, Danielle

2018-02-13

The psychological construct of 'therapeutic alliance' can be used to better understand the effectiveness of consultations, particularly goal setting for weight management. We analysed audio-recorded health coaching sessions during a weight loss trial to explore relationships between therapeutic alliance and various contextual factors. Audio recordings of 50 health coaching sessions were analysed. After assessing fidelity to the protocol, therapeutic alliance was measured using an adapted Working Alliance Inventory Observer-rated Short Version (WAI-O-S), and examined by (i) identifying relationships between contextual factors and WAI-O-S scores (Spearman's coefficients); (ii) testing the impact of preparatory exercises and body mass index on WAI-O-S scores (one-way analysis of variance and least-squared differences tests) and (iii) comparing differences in WAI-O-S scores based on relationship status, gender and follow-up session completion (independent samples t-tests). Fidelity was high (mean 88%). WAI-O-S total scores ranged from 55 to 70 (out of 84). Session duration was significantly correlated with WAI-O-S component of 'Bond' (r = 0.42, P = 0.002). Those who completed preparatory exercises had significantly higher total WAI-O-S scores, 'Goal' and 'Task' scores. Participants who completed the follow-up session scored significantly higher for 'Goal' compared to no follow-up. Spending more time in a session appears related to increased bonding, a key component of therapeutic alliance. Preparatory work may help build therapeutic alliance and agreement on goals appears to influence follow-up completion. These exploratory findings provide directions for research addressing the professional relationship in dietetic consultations for weight loss. © 2018 Dietitians Association of Australia.

The work ability index and single-item question: associations with sick leave, symptoms, and health--a prospective study of women on long-term sick leave.

PubMed

Ahlstrom, Linda; Grimby-Ekman, Anna; Hagberg, Mats; Dellve, Lotta

2010-09-01

This study investigated the association between the work ability index (WAI) and the single-item question on work ability among women working in human service organizations (HSO) currently on long-term sick leave. It also examined the association between the WAI and the single-item question in relation to sick leave, symptoms, and health. Predictive values of the WAI, the changed WAI, the single-item question and the changed single-item question were investigated for degree of sick leave, symptoms, and health. This cohort study comprised 324 HSO female workers on long-term (>60 days) sick leave, with follow-ups at 6 and 12 months. Participants responded to questionnaires. Data on work ability, sick leave, health, and symptoms were analyzed with regard to associations and predictability. Spearman correlation and mixed-model analysis were performed for repeated measurements over time. The study showed a very strong association between the WAI and the single-item question among all participants. Both the WAI and the single-item question showed similar patterns of associations with sick leave, health, and symptoms. The predictive value for the degree of sick leave and health-related quality of life (HRQoL) was strong for both the WAI and the single-item question, and slightly less strong for vitality, neck pain, both self-rated general and mental health, and behavioral and current stress. This study suggests that the single-item question on work ability could be used as a simple indicator for assessing the status and progress of work ability among women on long-term sick leave.

The First Annual West Antarctic Ice Sheet (WAIS) Science Workshop

NASA Technical Reports Server (NTRS)

Bindschadler, Robert A. (Editor)

1993-01-01

A compilation of abstracts presented at the workshop are presented. The goal was to answer the question, what is the future behavior and potential for rapid collapse of the West Antarctic Ice Sheet (WAIS)? The workshop was organized into four sessions corresponding to the four objectives identified as necessary to reach the WAIS workshop goal: history, current behavior, internal dynamics, and environmental interactions. Presentations were organized by their relevance to each objective, rather than by discipline.

Sea-level projections representing the deeply uncertain contribution of the West Antarctic ice sheet.

PubMed

Bakker, Alexander M R; Wong, Tony E; Ruckert, Kelsey L; Keller, Klaus

2017-06-20

There is a growing awareness that uncertainties surrounding future sea-level projections may be much larger than typically perceived. Recently published projections appear widely divergent and highly sensitive to non-trivial model choices . Moreover, the West Antarctic ice sheet (WAIS) may be much less stable than previous believed, enabling a rapid disintegration. Here, we present a set of probabilistic sea-level projections that approximates the deeply uncertain WAIS contributions. The projections aim to inform robust decisions by clarifying the sensitivity to non-trivial or controversial assumptions. We show that the deeply uncertain WAIS contribution can dominate other uncertainties within decades. These deep uncertainties call for the development of robust adaptive strategies. These decision-making needs, in turn, require mission-oriented basic science, for example about potential signposts and the maximum rate of WAIS-induced sea-level changes.

The Work Ability of Hong Kong Construction Workers in Relation to Individual and Work-Related Factors.

PubMed

Ng, Jacky Y K; Chan, Alan H S

2018-05-14

The shortage in Hong Kong of construction workers is expected to worsen in future due to the aging population and increasing construction activity. Construction work is dangerous and to help reduce the premature loss of construction workers due to work-related disabilities, this study measured the work ability of 420 Hong Kong construction workers with a Work Ability Index (WAI) which can be used to predict present and future work performance. Given the importance of WAI, in this study the effects of individual and work-related factors on WAI were examined to develop and validate a WAI model to predict how individual and work-related factors affect work ability. The findings will be useful for formulating a pragmatic intervention program to improve the work ability of construction workers and keep them in the work force.

A comparison of low IQ scores from the Reynolds Intellectual Assessment Scales and the Wechsler Adult Intelligence Scale-Third Edition.

PubMed

Umphress, Thomas B

2008-06-01

Twenty people with suspected intellectual disability took the Reynolds Intellectual Assessment Scales (RIAS; C. R. Reynolds & R. W. Kamphaus, 1998) and the Wechsler Adult Intelligence Scale-3rd Edition (WAIS-III; D. Wechsler, 1997) to see if the 2 IQ tests produced comparable results. A t test showed that the RIAS Composite Intelligence Index scores were significantly higher than WAIS-III Full Scale IQ scores at the alpha level of .01. There was a significant difference between the RIAS Nonverbal Intelligence and WAIS-III Performance Scale, but there was no significant difference between the RIAS Verbal Intelligence Index and the WAIS-III Verbal Scale IQ. The results raise questions concerning test selection for diagnosing intellectual disability and the use of the correlation statistic for comparing intelligence tests.

Development of WAIS-III General Ability Index Minus WMS-III memory discrepancy scores.

PubMed

Lange, Rael T; Chelune, Gordon J; Tulsky, David S

2006-09-01

Analysis of the discrepancy between intellectual functioning and memory ability has received some support as a useful means for evaluating memory impairment. In recent additions to Wechlser scale interpretation, the WAIS-III General Ability Index (GAI) and the WMS-III Delayed Memory Index (DMI) were developed. The purpose of this investigation is to develop base rate data for GAI-IMI, GAI-GMI, and GAI-DMI discrepancy scores using data from the WAIS-III/WMS-III standardization sample (weighted N = 1250). Base rate tables were developed using the predicted-difference method and two simple-difference methods (i.e., stratified and non-stratified). These tables provide valuable data for clinical reference purposes to determine the frequency of GAI-IMI, GAI-GMI, and GAI-DMI discrepancy scores in the WAIS-III/WMS-III standardization sample.

West Antarctic Ice Sheet cloud cover and surface radiation budget from NASA A-Train satellites

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scott, Ryan C.; Lubin, Dan; Vogelmann, Andrew M.

Clouds are an essential parameter of the surface energy budget influencing the West Antarctic Ice Sheet (WAIS) response to atmospheric warming and net contribution to global sea-level rise. A four-year record of NASA A-Train cloud observations is combined with surface radiation measurements to quantify the WAIS radiation budget and constrain the three-dimensional occurrence frequency, thermodynamic phase partitioning, and surface radiative effect of clouds over West Antarctica (WA). The skill of satellite-modeled radiative fluxes is confirmed through evaluation against measurements at four Antarctic sites (WAIS Divide Ice Camp, Neumayer, Syowa, and Concordia Stations). And due to perennial high-albedo snow and icemore » cover, cloud infrared emission dominates over cloud solar reflection/absorption leading to a positive net all-wave cloud radiative effect (CRE) at the surface, with all monthly means and 99.15% of instantaneous CRE values exceeding zero. The annual-mean CRE at theWAIS surface is 34 W m -2, representing a significant cloud-induced warming of the ice sheet. Low-level liquid-containing clouds, including thin liquid water clouds implicated in radiative contributions to surface melting, are widespread and most frequent in WA during the austral summer. Clouds warm the WAIS by 26 W m -2, in summer, on average, despite maximum offsetting shortwave CRE. Glaciated cloud systems are strongly linked to orographic forcing, with maximum incidence on the WAIS continuing downstream along the Transantarctic Mountains.« less

West Antarctic Ice Sheet cloud cover and surface radiation budget from NASA A-Train satellites

DOE PAGES

Scott, Ryan C.; Lubin, Dan; Vogelmann, Andrew M.; ...

2017-04-26

Clouds are an essential parameter of the surface energy budget influencing the West Antarctic Ice Sheet (WAIS) response to atmospheric warming and net contribution to global sea-level rise. A four-year record of NASA A-Train cloud observations is combined with surface radiation measurements to quantify the WAIS radiation budget and constrain the three-dimensional occurrence frequency, thermodynamic phase partitioning, and surface radiative effect of clouds over West Antarctica (WA). The skill of satellite-modeled radiative fluxes is confirmed through evaluation against measurements at four Antarctic sites (WAIS Divide Ice Camp, Neumayer, Syowa, and Concordia Stations). And due to perennial high-albedo snow and icemore » cover, cloud infrared emission dominates over cloud solar reflection/absorption leading to a positive net all-wave cloud radiative effect (CRE) at the surface, with all monthly means and 99.15% of instantaneous CRE values exceeding zero. The annual-mean CRE at theWAIS surface is 34 W m -2, representing a significant cloud-induced warming of the ice sheet. Low-level liquid-containing clouds, including thin liquid water clouds implicated in radiative contributions to surface melting, are widespread and most frequent in WA during the austral summer. Clouds warm the WAIS by 26 W m -2, in summer, on average, despite maximum offsetting shortwave CRE. Glaciated cloud systems are strongly linked to orographic forcing, with maximum incidence on the WAIS continuing downstream along the Transantarctic Mountains.« less

Orthogonal higher order structure and confirmatory factor analysis of the French Wechsler Adult Intelligence Scale (WAIS-III).

PubMed

Golay, Philippe; Lecerf, Thierry

2011-03-01

According to the most widely accepted Cattell-Horn-Carroll (CHC) model of intelligence measurement, each subtest score of the Wechsler Intelligence Scale for Adults (3rd ed.; WAIS-III) should reflect both 1st- and 2nd-order factors (i.e., 4 or 5 broad abilities and 1 general factor). To disentangle the contribution of each factor, we applied a Schmid-Leiman orthogonalization transformation (SLT) to the standardization data published in the French technical manual for the WAIS-III. Results showed that the general factor accounted for 63% of the common variance and that the specific contributions of the 1st-order factors were weak (4.7%-15.9%). We also addressed this issue by using confirmatory factor analysis. Results indicated that the bifactor model (with 1st-order group and general factors) better fit the data than did the traditional higher order structure. Models based on the CHC framework were also tested. Results indicated that a higher order CHC model showed a better fit than did the classical 4-factor model; however, the WAIS bifactor structure was the most adequate. We recommend that users do not discount the Full Scale IQ when interpreting the index scores of the WAIS-III because the general factor accounts for the bulk of the common variance in the French WAIS-III. The 4 index scores cannot be considered to reflect only broad ability because they include a strong contribution of the general factor.

Postoperative complications following intraoperative radiotherapy in abdominopelvic malignancy: A single institution analysis of 113 consecutive patients.

PubMed

Abdelfatah, Eihab; Page, Andrew; Sacks, Justin; Pierorazio, Phillip; Bivalacqua, Trinity; Efron, Jonathan; Terezakis, Stephanie; Gearhart, Susan; Fang, Sandy; Safar, Bashar; Pawlik, Timothy M; Armour, Elwood; Hacker-Prietz, Amy; Herman, Joseph; Ahuja, Nita

2017-06-01

Intraoperative radiotherapy (IORT) has advantages over external beam radiation therapy (EBRT). Few studies have described side effects associated with its addition. We evaluated our institution's experience with abdominopelvic IORT to assess safety by postoperative complication rates. Prospectively collected IRB-approved database of all patients receiving abdominopelvic IORT (via high dose rate brachytherapy) at Johns Hopkins Hospital between November 2006 and May 2014 was reviewed. Patients were discussed in multidisciplinary conferences. Those selected for IORT were patients for whom curative intent resection was planned for which IORT could improve margin-negative resection and optimize locoregional control. Perioperative complications were classified via Clavien-Dindo scale for postoperative surgical complications. A total of 113 patients were evaluated. Most common diagnosis was sarcoma (50/113, 44%) followed by colorectal cancer (45/113, 40%), most of which were recurrent (84%). There were no perioperative deaths. A total of 57% of patients experienced a complication Grade II or higher: 24% (27/113) Grade II; 27% (30/113) Grade III; 7% (8/113) Grade IV. Wound complications were most common (38%), then gastrointestinal (25%). No radiotherapy variables were significantly associated with complications on uni/multi-variate analysis. Our institution's experience with IORT demonstrated historically expected postoperative complication rates. IORT is safe, with acceptable perioperative morbidity. © 2017 Wiley Periodicals, Inc.

The hyperthermic intraoperative intraperitoneal chemotherapy in the treatment of advanced abdominopelvic cancer. Personal experience on 103 procedures during a seventeen year period in a single Italian center.

PubMed

Di Miceli, D; Cina, C; Fiorillo, C; Doglietto, G B; Alfieri, S

2018-02-01

Integration of different therapeutic strategies in cancer surgery in the last years has led from treating primary lesions to the surgical treatment of metastases. The purpose of this paper is to report a single Italian center experience of treatment of peritoneal carcinosis of the abdominopelvic malignancies. 103 HIPEC procedures were performed in 17 years on 94 selected patients affected by abdominopelvic cancer. The PCI score was calculated at laparotomy. The CC score was calculated before doing HIPEC. HIPEC was carried out according to the Coliseum technique. The surgical cytoreduction allowed 89 patients to be subjected to HIPEC treatment with a CC score 0; 9 patients with a CC 1; 3 patients with a CC 2 and 2 patients with a CC 3. In 22 patients postoperative complications were recorded. No operative mortality occurred. The median follow-up of 53 months shows a rate of survival equivalent to 49 %, with a relapse in 46 patients, 29 of them reached exitus. The surgical resection alone for patients affected by advanced cancer with peritoneal carcinomatosis cannot be considered a sufficient treatment any longer and HIPEC would help to prolong survival in these patients.

Contemporary Role of Embolization of Solid Organ and Pelvic Injuries in Polytrauma Patients

PubMed Central

Ptohis, Nikolaos D.; Charalampopoulos, Georgios; Abou Ali, Adham N.; Avgerinos, Efthymios D.; Mousogianni, Iliana; Filippiadis, Dimitrios; Karydas, George; Gravanis, Miltiadis; Pagoni, Stamatina

2017-01-01

Abdominopelvic trauma (APT) remains a leading cause of morbidity and mortality in the 15- to 44-year-old age group in the Western World. It can be life-threatening as abdominopelvic organs, specifically those in the retroperitoneal space, can bleed profusely. APT is divided into blunt and penetrating types. While surgery is notably considered as a definitive solution for bleeding control, it is not always the optimum treatment for the stabilization of a polytrauma patient. Over the past decades, there has been a shift toward more sophisticated strategies, such as non-operative management of abdominopelvic vascular trauma for haemodynamically stable patients. Angiographic embolization for bleeding control following blunt and/or penetrating intra- and retroperitoneal injuries has proven to be safe and effective. Embolization can achieve hemostasis and salvage organs without the morbidity of surgery, and the development and refinement of embolization techniques has widened the indications for non-operative treatment in solid organ injury. Moreover, advances in computed tomography provided more efficient scanning times with improved image quality. While surgery is still usually recommended for patients with penetrating injuries, non-operative management can be effectively used as well as an alternative treatment. We review indications, technical considerations, efficacy, and complication rates of angiographic embolization in APT. PMID:28824919

Prospective randomized trial of iohexol 350 versus meglumine sodium diatrizoate as an oral contrast agent for abdominopelvic computed tomography.

PubMed

Peterson, Christine M; Lin, Michael; Pilgram, Thomas; Heiken, Jay P

2011-01-01

To compare the efficacy and patient tolerance of iohexol and meglumine sodium diatrizoate as oral contrast agents for computed tomography (CT). One hundred patients were randomly assigned to drink 1000 mL of either meglumine sodium diatrizoate or iohexol 350 before their abdominopelvic CT examination. The images were evaluated independently and in a blinded fashion by 2 radiologists who scored the extent and density of bowel opacification. Attenuation value measurements were obtained in representative areas of each gastrointestinal tract segment (stomach, duodenum, jejunum, ileum, and colon) by a research technologist. Patients' tolerance of the oral contrast agent was assessed through a questionnaire administered immediately after the CT and with a follow-up phone call 2 to 3 days later. For most of the bowel, there was no statistically significant difference in the extent or degree of opacification between the 2 contrast agents. Opacification of the ileum was better with iohexol. There was no statistically significant difference between the 2 agents in adverse effects. Patients had a small but statistically significant preference for the taste of iohexol. Iohexol 350 is a satisfactory oral contrast agent for abdominopelvic CT. It opacifies the gastrointestinal tract as well as meglumine sodium diatrizoate does, and patients prefer the taste of iohexol to that of diatrizoate.

Abdominopelvic kinesiotherapy for pelvic floor muscle training: a tested proposal in different groups.

PubMed

Botelho, Simone; Martinho, Natalia Miguel; Silva, Valéria Regina; Marques, Joseane; Alves, Fabiola Kenia; Riccetto, Cássio

2015-12-01

This video's proposal was to present one of the pelvic floor muscle (PFM) training programs used in our research, and to study the effects of abdominopelvic kinesiotherapy on female PFM function. A total of 82 women participated in this study, 11 nulliparous, 13 primiparous pregnant, 20 primiparous postpartum and 38 postmenopausal women, who were evaluated first by digital palpation, then by either electromyography or vaginal dynamometry to investigate their PFM strength, followed by ICIQ UI-SF and ICIQ-OAB to evaluate urinary symptoms. This intervention protocol lasted for 60 min, three times a week, with a total of 10 sessions, and was supervised by a physiotherapist, using a gym ball, according to Marques and collaborators. A significant increase in PFM strength was observed by digital palpation in all groups. This finding was confirmed by electromyography in both pregnant (p = 0.0001) and postpartum (p = 0.0001) groups, as well as in 20 of the 38 women from the postmenopausal group (p = 0.003) then by vaginal dynamometry (p = 0.02) in the rest of the women (18) from the same group, with a concomitant decrease in urinary symptoms (p < 0.05). The abdominopelvic kinesiotherapy program promotes an increase in pelvic floor muscle strength and a decrease in urinary symptoms.

Conceptual elaboration versus direct lexical access in WAIS-similarities: differential effects of white-matter lesions and gray matter volumes.

PubMed

Fernaeus, Sven-Erik; Hellström, Åke

2017-09-18

Wechsler Adult Intelligence Scale (WAIS) subscale Similarities have been classified as a test of either verbal comprehension or of inductive reasoning. The reason may be that items divide into two categories. We tested the hypothesis of heterogeneity of items in WAIS-Similarities. Consecutive patients at a memory clinic and healthy controls participated in the study. White-matter hyperintensities (WMHs) and normalized temporal lobe volumes were measured based on Magnetic resonance Imaging (MRI), and tests of verbal memory and attention were used in addition to WAIS-Similarities to collect behavioural data. Factor analysis supported the hypothesis that two factors are involved in the performance of WAIS-similarities: (1) semiautomatic lexical access and (2) conceptual elaboration. These factors were highly correlated but provided discriminative diagnostic information: In logistic regression analyses, scores of the lexical access factor and of the conceptual elaboration factor discriminated patients with mild cognitive impairment from Alzheimer's disease patients and from healthy controls, respectively. High scores of WMH, indicating periventricular white-matter lesions, predicted factor scores of direct lexical access but not those of conceptual elaboration, which were predicted only by medial and lateral temporal lobe volumes.

A first-in-human, randomized, controlled, subject- and reviewer-blinded multicenter study of Actamax™ Adhesion Barrier.

PubMed

Trew, Geoffrey H; Pistofidis, George A; Brucker, Sara Y; Krämer, Bernhard; Ziegler, Nicole M; Korell, Matthias; Ritter, Henning; McConnachie, Alex; Ford, Ian; Crowe, Alison M; Estridge, Trudy D; Diamond, Michael P; De Wilde, Rudy L

2017-02-01

Post-surgical adhesions remain a significant concern following abdominopelvic surgery. This study was to assess safety, manageability and explore preliminary efficacy of applying a degradable hydrogel adhesion barrier to areas of surgical trauma following gynecologic laparoscopic abdominopelvic surgery. This first-in-human, prospective, randomized, multicenter, subject- and reviewer-blinded clinical study was conducted in 78 premenopausal women (18-46 years) wishing to maintain fertility and undergoing gynecologic laparoscopic abdominopelvic surgery with planned clinically indicated second-look laparoscopy (SLL) at 4-12 weeks. The first two patients of each surgeon received hydrogel, up to 30 mL sprayed over all sites of surgical trauma, and were assessed for safety and application only (n = 12). Subsequent subjects (n = 66) were randomized 1:1 to receive either hydrogel (Treatment, n = 35) or not (Control, n = 31); 63 completed the SLL. No adverse event was assessed as serious, or possibly device related. None was severe or fatal. Adverse events were reported for 17 treated subjects (17/47, 36.2%) and 13 Controls (13/31, 41.9%). For 95.7% of treated subjects, surgeons found the device "easy" or "very easy" to use; in 54.5%, some residual material was evident at SLL. For 63 randomized subjects who completed the SLL, adjusted between-group difference in the change from baseline adhesion score demonstrated a 41.4% reduction for Treatment compared with Controls (p = 0.017), with a 49.5% reduction (p = 0.008) among myomectomy subjects (n = 34). Spray application of a degradable hydrogel adhesion barrier during gynecologic laparoscopic abdominopelvic surgery was performed easily and safely, without evidence of clinically significant adverse outcomes. Data suggest the hydrogel was effective in reducing postoperative adhesion development, particularly following myomectomy.

Predictor of Severe Gastroduodenal Toxicity After Stereotactic Body Radiotherapy for Abdominopelvic Malignancies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bae, Sun Hyun; Kim, Mi-Sook, E-mail: mskim@kcch.re.kr; Cho, Chul Koo

2012-11-15

Purpose: To identify the predictors for the development of severe gastroduodenal toxicity (GDT) in patients treated with stereotactic body radiotherapy (SBRT) using 3 fractionations for abdominopelvic malignancies. Methods and Materials: From 2001 to 2011, 202 patients with abdominopelvic malignancies were treated with curative-intent SBRT. Among these patients, we retrospectively reviewed the clinical records of 40 patients with the eligibility criteria as follows: 3 fractionations, follow-up period {>=}1 year, absence of previous radiation therapy (RT) history or combination of external-beam RT and the presence of gastroduodenum (GD) that received a dose higher than 20% of prescribed dose. The median SBRT dosemore » was 45 Gy (range, 33-60 Gy) with 3 fractions. We analyzed the clinical and dosimetric parameters, including multiple dose-volume histogram endpoints: V{sub 20} (volume of GD that received 20 Gy), V{sub 25}, V{sub 30}, V{sub 35}, and D{sub max} (the maximum point dose). The grade of GDT was defined by the National Cancer Institute Common Toxicity Criteria version 4.0, and GDT {>=}grade 3 was defined as severe GDT. Results: The median time to the development of severe GDT was 6 months (range, 3-12 months). Severe GDT was found in 6 patients (15%). D{sub max} was the best dosimetric predictor for severe GDT. D{sub max} of 35 Gy and 38 Gy were respectively associated with a 5% and 10% probability of the development of severe GDT. A history of ulcer before SBRT was the best clinical predictor on univariate analysis (P=.0001). Conclusions: We suggest that D{sub max} is a valuable predictor of severe GDT after SBRT using 3 fractionations for abdominopelvic malignancies. A history of ulcer before SBRT should be carefully considered as a clinical predictor, especially in patients who receive a high dose to GD.« less

Weight-adapted iodinated contrast media administration in abdomino-pelvic CT: Can image quality be maintained?

PubMed

Perrin, E; Jackson, M; Grant, R; Lloyd, C; Chinaka, F; Goh, V

2018-02-01

In many centres, a fixed method of contrast-media administration is used for CT regardless of patient body habitus. The aim of this trial was to assess contrast enhancement of the aorta, portal vein, liver and spleen during abdomino-pelvic CT imaging using a weight-adapted contrast media protocol compared to the current fixed dose method. Thirty-nine oncology patients, who had previously undergone CT abdomino-pelvic imaging at the institution using a fixed contrast media dose, were prospectively imaged using a weight-adapted contrast media dose (1.4 ml/kg). The two sets of images were assessed for contrast enhancement levels (HU) at locations in the liver, aorta, portal vein and spleen during portal-venous enhancement phase. The t-test was used to compare the difference in results using a non-inferiority margin of 10 HU. When the contrast dose was tailored to patient weight, contrast enhancement levels were shown to be non-inferior to the fixed dose method (liver p < 0.001; portal vein p = 0.003; aorta p = 0.001; spleen p = 0.001). As a group, patients received a total contrast dose reduction of 165 ml using the weight-adapted method compared to the fixed dose method, with a mean cost per patient of £6.81 and £7.19 respectively. Using a weight-adapted method of contrast media administration was shown to be non-inferior to a fixed dose method of contrast media administration. Patients weighing 76 kg, or less, received a lower contrast dose which may have associated cost savings. A weight-adapted contrast media protocol should be implemented for portal-venous phase abdomino-pelvic CT for oncology patients with adequate renal function (>70 ml/min/1.73 m 2 ). Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.

High-Grade Serous Ovarian Cancer: Use of Machine Learning to Predict Abdominopelvic Recurrence on CT on the Basis of Serial Cancer Antigen 125 Levels.

PubMed

Shinagare, Atul B; Balthazar, Patricia; Ip, Ivan K; Lacson, Ronilda; Liu, Joyce; Ramaiya, Nikhil; Khorasani, Ramin

2018-05-19

The aim of this study was to use machine learning to predict abdominal recurrence on CT on the basis of serial cancer antigen 125 (CA125) levels in patients with advanced high-grade serous ovarian cancer on surveillance. This institutional review board-approved, HIPAA-compliant, retrospective, hypothesis-generating study included all 57 patients (mean age, 61 ± 11.2 years) with advanced high-grade serous ovarian cancer who underwent cytoreductive surgery from January to December 2012, followed by surveillance abdominopelvic CT and corresponding CA125 levels. A blinded radiologist reviewed abdominopelvic CT studies until recurrence was noted. Four measures of CA125 were assessed: actual CA125 levels at the time of CT, absolute change since prior CT, relative change since prior CT, and rate of change since prior CT. Using machine learning, support vector machine models were optimized and evaluated using 10-fold cross-validation to determine the CA125 measure most predictive of abdominal recurrence. The association of the most accurate CA125 measure was further analyzed using Cox proportional-hazards model along with age, tumor size, stage, and degree of cytoreduction. Rate of change in CA125 was most predictive of abdominal recurrence in a linear kernel support vector machine model and was significantly higher preceding CT studies showing abdominal recurrence (median 13.2 versus 0.6 units/month; P = .007). On multivariate analysis, a higher rate of CA125 increase was significantly associated with recurrence (hazard ratio, 1.02 per 10 units change; 95% confidence interval, 1.0006-1.04; P = .04). A higher rate of CA125 increase is associated with abdominal recurrence. The rate of increase of CA125 may help in the selection of patients who are most likely to benefit from abdominopelvic CT in surveillance of ovarian cancer. Copyright © 2018 American College of Radiology. Published by Elsevier Inc. All rights reserved.

Factors associated with work ability index (WAI) among intensive care units' (ICUs') nurses.

PubMed

Rostamabadi, Akbar; Zamanian, Zahra; Sedaghat, Zahra

2017-03-28

Work ability is a crucial occupational health issue in health care settings where a high physical and psychosocial work capacity is required and a high risk of disabling injuries and illnesses is predictable. This study aims to examine the association between the work ability index (WAI) and individual characterizations, workload, fatigue, and diseases among intensive care units' (ICUs') nurses. The study sample included 214 nurses selected by a random sampling method from a target population consisting of 321 registered nurses working in eight ICUs. Multiple linear regression analysis was used to test the association between WAI scores and each of the independent variables. Results of multivariate analysis revealed a strong and negative association between WAI scores and diseases (B=-5.82, 95% CI=-7.16, -4.48, P<0.001). Among the studied individual characterizations, body mass index (BMI) was significantly and inversely associated with WAI scores. A significant and negative association was also found between WAI scores and dimensions of MFI-20, such as general fatigue (B=-0.31, 95% CI=-0.53, -0.09, P=0.005) and physical fatigue (B=-0.44, 95% CI=-0.65, -0.23, P<0.001). From dimensions of workload, frustration (B=-0.04, 95% CI=-0.07, -0.02, P<0.001) and temporary demand (B=-0.04, 95% CI=-0.08, -0.0001, P=0.04) showed a negative and significant association with WAI scores, while performance showed a positive and significant association (B=0.04, 95% CI=0.01, 0.07, P=0.005). Based on the study findings, development of health care programs with the aim of setting up a healthy work environment characterized by a well-structured preventive attitude toward controlling diseases, and a well-designed organizational framework toward increasing the level of performance and motivation, reducing the level of fatigue, as well as reducing the workload, is necessary to promote work ability among ICUs' nurses.

Work ability index and perceived work ability as predictors of disability pension: a prospective study among Finnish municipal employees.

PubMed

Jääskeläinen, Anne; Kausto, Johanna; Seitsamo, Jorma; Ojajärvi, Anneli; Nygård, Clas-Håkan; Arjas, Elja; Leino-Arjas, Päivi

2016-06-01

We analyzed the work ability index (WAI) and its first item (work ability score, WAS) - and subsequent four-year changes thereof - as predictors of disability pension (DP). We linked survey responses of 5251 Finnish municipal employees, aged 44-58 years, to pension and death register data until 2009. Job content (physical, mental, or mixed) was based on observation. Baseline (1981) WAI was divided into poor (<27), moderate (28-36), and good/excellent (>37) and WAS into poor (0-5), moderate (6-7), and good/excellent (8-10). Four-year changes in these scores were classified as strong decline (

The psychometric properties of an Iranian translation of the Work Ability Index (WAI) questionnaire.

PubMed

Abdolalizadeh, M; Arastoo, A A; Ghsemzadeh, R; Montazeri, A; Ahmadi, K; Azizi, A

2012-09-01

This study was carried out to evaluate the psychometric properties of an Iranian translation of the Work Ability Index (WAI) questionnaire. In this methodological study, nurses and healthcare workers aged 40 years and older who worked in educational hospitals in Ahvaz (236 workers) in 2010, completed the questionnaire and 60 of the workers filled out the WAI questionnaire for the second time to ensure test-retest reliability. Forward-backward method was applied to translate the questionnaire from English into Persian. The psychometric properties of the Iranian translation of the WAI were assessed using the fallowing tests: Internal consistency (to test reliability), test-retest analysis, exploratory factor analysis (construct validity), discriminate validity by comparing the mean WAI score in two groups of the employees that had different levels of sick leave, criterion validity by determining the correlation between the Persian version of short form health survey (SF-36) and WAI score. Cronbach's alpha coefficient was estimated to be 0.79 and it was concluded that the internal consistency was high enough. The intraclass correlation coefficient was recognized to be 0.92. Factor analysis indicated three factors in the structure of the work ability including self-perceived work ability (24.5% of the variance), mental resources (22.23% of the variance), and presence of disease and health related limitation (18.55% of the variance). Statistical tests showed that this questionnaire was capable of discriminating two groups of employees who had different levels of sick leave. Criterion validity analysis showed that this instrument and all dimensions of the Iranian version of SF-36 were correlated significantly. Item correlation corrective for overlap showed the items tests had a good correlation except for one. The finding of the study showed that the Iranian version of the WAI is a reliable and valid measure of work ability and can be used both in research and practical activities.

The Work Ability of Hong Kong Construction Workers in Relation to Individual and Work-Related Factors

PubMed Central

Ng, Jacky Y. K.

2018-01-01

The shortage in Hong Kong of construction workers is expected to worsen in future due to the aging population and increasing construction activity. Construction work is dangerous and to help reduce the premature loss of construction workers due to work-related disabilities, this study measured the work ability of 420 Hong Kong construction workers with a Work Ability Index (WAI) which can be used to predict present and future work performance. Given the importance of WAI, in this study the effects of individual and work-related factors on WAI were examined to develop and validate a WAI model to predict how individual and work-related factors affect work ability. The findings will be useful for formulating a pragmatic intervention program to improve the work ability of construction workers and keep them in the work force. PMID:29758018

Evidence for the stability of the West Antarctic Ice Sheet divide for 1.4 million years

NASA Astrophysics Data System (ADS)

Hein, Andrew S.; Woodward, John; Marrero, Shasta M.; Dunning, Stuart A.; Steig, Eric J.; Freeman, Stewart P. H. T.; Stuart, Finlay M.; Winter, Kate; Westoby, Matthew J.; Sugden, David E.

2016-02-01

Past fluctuations of the West Antarctic Ice Sheet (WAIS) are of fundamental interest because of the possibility of WAIS collapse in the future and a consequent rise in global sea level. However, the configuration and stability of the ice sheet during past interglacial periods remains uncertain. Here we present geomorphological evidence and multiple cosmogenic nuclide data from the southern Ellsworth Mountains to suggest that the divide of the WAIS has fluctuated only modestly in location and thickness for at least the last 1.4 million years. Fluctuations during glacial-interglacial cycles appear superimposed on a long-term trajectory of ice-surface lowering relative to the mountains. This implies that as a minimum, a regional ice sheet centred on the Ellsworth-Whitmore uplands may have survived Pleistocene warm periods. If so, it constrains the WAIS contribution to global sea level rise during interglacials to about 3.3 m above present.

Demographic and occupational determinants of the work ability of firemen.

PubMed

Firoozeh, Marjan; Saremi, Mahnaz; Kavousi, Amir; Maleki, Azam

2017-01-24

Firefighters tackle various stressors that affect their health and job performance; therefore, assessment of their work ability is necessary. This study aimed to investigate the demographic and occupational determinants of the work ability of firemen. In this cross-sectional study, 375 firemen working in Tehran Fire Department were randomly selected. Demographic, occupational, and work ability index (WAI) questionnaires were applied as research tools. The mean firemen's WAI score was relatively high. There were significant relationships between WAI and age, body mass index, work experience, and weekly leisure-time physical exercise hours. Single employees, those who did not have extra jobs and did not smoke, had greater scores compared to their counterparts. Poisson regression revealed that age and weekly leisure-time physical exercise hours could affect WAI significantly. Although Iranian firemen revealed good work ability, recognizing factors affecting this ability and preparing facilities to promote their function is necessary.

Education-stratified base-rate information on discrepancy scores within and between the Wechsler Adult Intelligence Scale--Third Edition and the Wechsler Memory Scale--Third Edition.

PubMed

Dori, Galit A; Chelune, Gordon J

2004-06-01

The Wechsler Adult Intelligence Scale--Third Edition (WAIS-III; D. Wechsler, 1997a) and the Wechsler Memory Scale--Third Edition (WMS-III; D. Wechsler, 1997b) are 2 of the most frequently used measures in psychology and neuropsychology. To facilitate the diagnostic use of these measures in the clinical decision-making process, this article provides information on education-stratified, directional prevalence rates (i.e., base rates) of discrepancy scores between the major index scores for the WAIS-III, the WMS-III, and between the WAIS-III and WMS-III. To illustrate how such base-rate data can be clinically used, this article reviews the relative risk (i.e., odds ratio) of empirically defined "rare" cognitive deficits in 2 of the clinical samples presented in the WAIS-III--WMS-III Technical Manual (The Psychological Corporation, 1997). ((c) 2004 APA, all rights reserved)

WAIS Performance in Unincarcerated Groups of MMPI-Defined Sociopaths and Normal Controls

ERIC Educational Resources Information Center

Allain, Albert N.

1974-01-01

This investigation examines WAIS performance in groups of 32 sociopaths and 33 normal controls defined by Minnesota Multiphasic Personality Inventory criteria. Sociopaths and normal controls show no differences in overall level of intellectual functioning. (Author)

Self-Reported Poor Work Ability--An Indicator of Need for Rehabilitation? A Cross-Sectional Study of a Sample of German Employees.

PubMed

Bethge, Matthias; Spanier, Katja; Neugebauer, Tjark; Mohnberg, Inka; Radoschewski, Friedrich Michael

2015-11-01

The purpose of this study was to assess associations of self-reported work ability as measured by the Work Ability Index (WAI) with modifiable behavioral and occupational health risks, health service utilization, and intended rehabilitation and pension requests. This is a cross-sectional study of a random sample of German employees aged 40-54 yrs on sickness benefits in 2012 (trial registration: DRKS00004824). In total, 1312 male and 1502 female employees were included in the analyses. Low WAI scores (i.e., <37 points) were associated with a higher prevalence of occupational and behavioral health risks; a higher likelihood of frequent visits to general, somatic, and psychologic specialists as well as hospital stays; and four to six times higher risks of intended rehabilitation and pension requests. A two-item version of the WAI was as strongly associated with intended rehabilitation and pension requests as the total score. This study indicates that the WAI is a sensitive screening tool to identify workers on sick leave with a probable need for rehabilitation. The WAI could support the assessment of need for rehabilitation by occupational health services in return-to-work strategies, which include the opportunity to access multiprofessional rehabilitation.

Multiple dimensions of work-related risk factors and their relationship to work ability among industrial workers in Iran.

PubMed

Mokarami, Hamidreza; Mortazavi, Seyed Bagher; Asgari, Ali; Choobineh, Alireza; Stallones, Lorann

2017-09-01

The present study was designed to investigate the simultaneous effects of physical, psychosocial and other work-related risk factors on the work ability index (WAI) score among industrial workers. This study used a cross-sectional design with a questionnaire survey. A total of 280 workers were included in the study. Data were collected using three questionnaires including the Persian version of the WAI, the Persian version of the job content questionnaire and an author-developed measure (to assess work-related factors, health-related factors and socio-demographic characteristics). The majority of the participants were young, but they had poor WAI scores (mean 37.3 ± 6.4) and 44.3% of them had poor or moderate work ability. Occupational accidents and injuries were found to be the strongest predictors of WAI scores. Additionally, there was a strong association between WAI scores and supervisor support, skill discretion, occupational training, sleep quality, work nature and educational level. Intervention programs should focus on improving supervisor support, sleep quality, job skills and knowledge and on decreasing physical and mental work demands. Additionally, implementing a comprehensive occupational health and ergonomics program for controlling and reducing hazardous working environments and occupational injury rates should be considered.

Outcome of Blunt Abdominal Traumas with Stable Hemodynamic and Positive FAST Findings.

PubMed

Behboodi, Firooz; Mohtasham-Amiri, Zahra; Masjedi, Navid; Shojaie, Reza; Sadri, Peyman

2016-01-01

Focused assessment with sonography for trauma (FAST) is a highly effective first screening tool for initial classification of abdominal trauma patients. The present study was designed to evaluate the outcome of patients with blunt abdominal trauma and positive FAST findings. The present prospective cross-sectional study was done on patients over 7 years old with normal abdominal examination, positive FAST findings, and available abdominopelvic computed tomography (CT) scan findings. The frequency of need for laparotomy as well as its probable risk factors were calculated. 180 patients were enrolled (mean age: 28.0 ± 11.5 years; 76.7% male). FAST findings were confirmed by abdominopelvic CT scan in only 124 (68.9%) cases. Finally, 12 (6.6%) patients needed laparotomy. Mean age of those in need of laparotomy was significantly higher than others (36.75 ± 11.37 versus 27.34 ± 11.37, p = 0.006). Higher grading of spleen (p = 0.001) and hepatic (p = 0.038) ruptures increased the probability of need for laparotomy. 68.9% of the positive FAST findings in patients with blunt abdominal trauma and stable hemodynamics was confirmed by abdominopelvic CT scan and only 6.6% needed laparotomy. Simultaneous presence of free fluid and air in the abdominal area, old age, and higher grading o solid organ injuries were factors that had a significant correlation with need for laparotomy.

Model-based iterative reconstruction for reduction of radiation dose in abdominopelvic CT: comparison to adaptive statistical iterative reconstruction.

PubMed

Yasaka, Koichiro; Katsura, Masaki; Akahane, Masaaki; Sato, Jiro; Matsuda, Izuru; Ohtomo, Kuni

2013-12-01

To evaluate dose reduction and image quality of abdominopelvic computed tomography (CT) reconstructed with model-based iterative reconstruction (MBIR) compared to adaptive statistical iterative reconstruction (ASIR). In this prospective study, 85 patients underwent referential-, low-, and ultralow-dose unenhanced abdominopelvic CT. Images were reconstructed with ASIR for low-dose (L-ASIR) and ultralow-dose CT (UL-ASIR), and with MBIR for ultralow-dose CT (UL-MBIR). Image noise was measured in the abdominal aorta and iliopsoas muscle. Subjective image analyses and a lesion detection study (adrenal nodules) were conducted by two blinded radiologists. A reference standard was established by a consensus panel of two different radiologists using referential-dose CT reconstructed with filtered back projection. Compared to low-dose CT, there was a 63% decrease in dose-length product with ultralow-dose CT. UL-MBIR had significantly lower image noise than L-ASIR and UL-ASIR (all p<0.01). UL-MBIR was significantly better for subjective image noise and streak artifacts than L-ASIR and UL-ASIR (all p<0.01). There were no significant differences between UL-MBIR and L-ASIR in diagnostic acceptability (p>0.65), or diagnostic performance for adrenal nodules (p>0.87). MBIR significantly improves image noise and streak artifacts compared to ASIR, and can achieve radiation dose reduction without severely compromising image quality.

Patient satisfaction and psychological well-being after internet-based cognitive behavioral stress management (IB-CBSM) for women with preterm labor: A randomized controlled trial.

PubMed

Scherer, S; Alder, J; Gaab, J; Berger, T; Ihde, K; Urech, C

2016-01-01

Despite its value for the management of psychological burden, little is known about the efficacy of and patient satisfaction with internet-based cognitive behavioral stress management (IB-CBSM) for women with preterm labor. The present study sets out to analyze stress/anxiety reduction, patient satisfaction and patient's working alliance in a group of 58 women with preterm labor participating in an online psychological stress management project. As part of the project, women were randomly assigned to online stress management or a control condition. Levels of stress and anxiety decreased significantly in both conditions from pre- to post-treatment measure. Participants in IB-CBSM reported significant higher working alliance inventory (WAI) scores in the task and goal subscale (p<.001; p<.05) than women in the control condition. In Addition the IB-CBSM group showed significant correlations of the WAI subscale task and goal and the stress/anxiety outcome. Regarding patient satisfaction, women in the IB-CBSM reported significantly higher satisfaction scores (p<.001) than women in the control condition. WAI explained nearly 40% of the variance in patient satisfaction. Furthermore, WAI mediates, at least in part, the relationship between group condition and patient satisfaction. The current analysis indicated that participants in IB-CBSM had higher WAI scores and were more satisfied with the program. In addition only the IB-CBSM group showed significant correlations of the WAI with the stress/anxiety reduction outcome. Based on these findings, it can be presumed that measures of agreement with working alliance parameters, especially task and goal components, are substantially important for more effective and satisfactory therapeutic interventions. Copyright © 2015 Elsevier Inc. All rights reserved.

Work ability as prognostic risk marker of disability pension: single-item work ability score versus multi-item work ability index.

PubMed

Roelen, Corné A M; van Rhenen, Willem; Groothoff, Johan W; van der Klink, Jac J L; Twisk, Jos W R; Heymans, Martijn W

2014-07-01

Work ability predicts future disability pension (DP). A single-item work ability score (WAS) is emerging as a measure for work ability. This study compared single-item WAS with the multi-item work ability index (WAI) in its ability to identify workers at risk of DP. This prospective cohort study comprised 11 537 male construction workers, who completed the WAI at baseline and reported DP after a mean 2.3 years of follow-up. WAS and WAI were calibrated for DP risk predictions with the Hosmer-Lemeshow (H-L) test and their ability to discriminate between high- and low-risk construction workers was investigated with the area under the receiver operating characteristic curve (AUC). At follow-up, 336 (3%) construction workers reported DP. Both WAS [odds ratio (OR) 0.72, 95% confidence interval (95% CI) 0.66-0.78] and WAI (OR 0.57, 95% CI 0.52-0.63) scores were associated with DP at follow-up. The WAS showed miscalibration (H-L model χ (�)=10.60; df=3; P=0.01) and poorly discriminated between high- and low-risk construction workers (AUC 0.67, 95% CI 0.64-0.70). In contrast, calibration (H-L model χ �=8.20; df=8; P=0.41) and discrimination (AUC 0.78, 95% CI 0.75-0.80) were both adequate for the WAI. Although associated with the risk of future DP, the single-item WAS poorly identified male construction workers at risk of DP. We recommend using the multi-item WAI to screen for risk of DP in occupational health practice.

Evaluating WAIS-IV structure through a different psychometric lens: structural causal model discovery as an alternative to confirmatory factor analysis.

PubMed

van Dijk, Marjolein J A M; Claassen, Tom; Suwartono, Christiany; van der Veld, William M; van der Heijden, Paul T; Hendriks, Marc P H

Since the publication of the WAIS-IV in the U.S. in 2008, efforts have been made to explore the structural validity by applying factor analysis to various samples. This study aims to achieve a more fine-grained understanding of the structure of the Dutch language version of the WAIS-IV (WAIS-IV-NL) by applying an alternative analysis based on causal modeling in addition to confirmatory factor analysis (CFA). The Bayesian Constraint-based Causal Discovery (BCCD) algorithm learns underlying network structures directly from data and assesses more complex structures than is possible with factor analysis. WAIS-IV-NL profiles of two clinical samples of 202 patients (i.e. patients with temporal lobe epilepsy and a mixed psychiatric outpatient group) were analyzed and contrasted with a matched control group (N = 202) selected from the Dutch standardization sample of the WAIS-IV-NL to investigate internal structure by means of CFA and BCCD. With CFA, the four-factor structure as proposed by Wechsler demonstrates acceptable fit in all three subsamples. However, BCCD revealed three consistent clusters (verbal comprehension, visual processing, and processing speed) in all three subsamples. The combination of Arithmetic and Digit Span as a coherent working memory factor could not be verified, and Matrix Reasoning appeared to be isolated. With BCCD, some discrepancies from the proposed four-factor structure are exemplified. Furthermore, these results fit CHC theory of intelligence more clearly. Consistent clustering patterns indicate these results are robust. The structural causal discovery approach may be helpful in better interpreting existing tests, the development of new tests, and aid in diagnostic instruments.

[Relationship between occupational stress and working ability of workers in a petroleum processing enterprise in high altitude area].

PubMed

Ma, X M; Kang, H L; Shi, C B; Li, Y; Wu, Y F; Liu, Z H; Wang, G; Lei, H Y

2017-12-20

Objective: To investigate the relationship between occupational stress and working ability of workers in a petroleum processing enterprise in a high altitude area. Methods: A total of 728 workers in a petroleum processing enterprise at an altitude of 2850 m were subjected to a survey using Occupational Stress Inventory (OSI) , Work Ability Index (WAI) Scale, Occupational Role Questionnaire (ORQ) , Personal Strain Questionnaire (PSQ) , and Personal Resource Questionnaire (PRQ) from May 2014 to August 2016. Results: Of the 728 workers, 55 (7.6%) had a poor working ability, moderate in 262 (35.9%) , and good in 411 (56.5%). There were significant differences in WAI between the workers with different types of work, sexes, ages, and working years ( P <0.05). There was a significant difference in WAI between different occupational stress groups ( P <0.05). WAI was negatively correlated with ORQ score and PSQ score ( r (s)=-0.387, P <0.05; r (s)=-0.467, P <0.05) and positively correlated with PRQ score ( r (s)=0.343, P <0.05). The multiple linear regression analysis showed that high ORQ score and PSQ score were the inhibitory factors for high WAI ( B =-0.058; B =-0.082) and high PRQ score was a contributing factor for high WAI ( B =0.029) . Conclusion: Occupational stress is an influencing factor for the working ability of workers in the petroleum processing enterprise in the high altitude area. Hypoxia in high altitude area may further reduce the working ability. In order to reduce occupational stress and improve work ability, it should be considered to strengthen skills training, improve the working environment, and pay attention to mental health.

Health check documentation of psychosocial factors using the WAI.

PubMed

Uronen, L; Heimonen, J; Puukka, P; Martimo, K-P; Hartiala, J; Salanterä, S

2017-03-01

Health checks in occupational health (OH) care should prevent deterioration of work ability and promote well-being at work. Documentation of health checks should reflect and support continuity of prevention and practice. To analyse how OH nurses (OHNs) undertaking health checks document psychosocial factors at work and use the Work Ability Index (WAI). Analysis of two consecutive OHN health check records and WAI scores with statistical analyses and annotations of 13 psychosocial factors based on a publicly available standard on psychosocial risk management: British Standards Institution specification PAS 1010, part of European Council Directive 89/391/EEC, with a special focus on work-related stress and workplace violence. We analysed health check records for 196 employees. The most frequently documented psychosocial risk factors were home-work interface, work environment and equipment, job content, workload and work pace and work schedule. The correlations between the number of documented risk and non-risk factors and WAI scores were significant: OHNs documented more risk factors in employees with lower WAI scores. However, documented psychosocial risk factors were not followed up, and the OHNs' most common response to detected psychosocial risks was an appointment with a physician. The number of psychosocial risk factors documented by OHNs correlated with subjects' WAI scores. However, the documentation was not systematic and the interventions were not always relevant. OHNs need a structure to document psychosocial factors and more guidance in how to use the documentation as a tool in their decision making in health checks. © The Author 2016. Published by Oxford University Press on behalf of the Society of Occupational Medicine. All rights reserved. For Permissions, please email: journals.permissions@oup.com

Working alliance, interpersonal trust and perceived coercion in mental health review hearings

PubMed Central

2011-01-01

Background There is some evidence that when mental health commitment hearings are held in accordance with therapeutic jurisprudence principles they are perceived as less coercive, and more just in their procedures leading to improved treatment adherence and fewer hospital readmissions. This suggests an effect of the hearing on therapeutic relationships. We compared working alliance and interpersonal trust in clinicians and forensic patients, whose continued detentions were reviewed by two different legal review bodies according to their legal category. Methods The hearings were rated as positive or negative by patients and treating psychiatrists using the MacArthur scales for perceived coercion, perceived procedural justice (legal and medical) and for the impact of the hearing. We rated Global assessment of Function (GAF), Positive and Negative Symptom Scale (PANSS), Working Alliance Inventory (WAI) and Interpersonal Trust in Physician (ITP) scales six months before the hearing and repeated the WAI and ITP two weeks before and two weeks after the hearing, for 75 of 83 patients in a forensic medium and high secure hospital. Results Psychiatrists agreed with patients regarding the rating of hearings. Patients rated civil hearings (MHTs) more negatively than hearings under insanity legislation (MHRBs). Those reviewed by MHTs had lower scores for WAI and ITP. However, post-hearing WAI and ITP scores were not different from baseline and pre-hearing scores. Using the receiver operating characteristic, baseline WAI and ITP scores predicted how patients would rate the hearings, as did baseline GAF and PANSS scores. Conclusions There was no evidence that positively perceived hearings improved WAI or ITP, but some evidence showed that negatively perceived hearings worsened them. Concentrating on functional recovery and symptom remission remains the best strategy for improved therapeutic relationships. PMID:22074788

Physical exercise at the workplace prevents deterioration of work ability among healthcare workers: cluster randomized controlled trial.

PubMed

Jakobsen, Markus D; Sundstrup, Emil; Brandt, Mikkel; Jay, Kenneth; Aagaard, Per; Andersen, Lars L

2015-11-25

Imbalance between individual resources and work demands can lead to musculoskeletal disorders and reduced work ability. The purpose of this study was to investigate the effect of workplace- versus home-based physical exercise on work ability among healthcare workers. Two hundred female healthcare workers (Age: 42.0, BMI: 24.1, work ability index [WAI]: 43.1) from 18 departments at three Danish hospitals participated (Copenhagen, Denmark, Aug 2013-Jan 2014). Participants were randomly allocated at the cluster level to 10 weeks of: 1) workplace physical exercise (WORK) performed during working hours for 5x10 min per week and up to 5 group-based coaching sessions on motivation for regular physical exercise, or 2) home-based physical exercise (HOME) performed during leisure time for 5x10 min per week. Both groups received ergonomic counseling on patient handling and use of lifting aides. The main outcome measure was the change from baseline to 10-week follow-up in WAI. Significant group by time interaction was observed for WAI (p < 0.05). WAI at follow-up was 1.1 (0.3 to 1.8) higher in WORK compared with HOME corresponding to a small effect size (Cohens'd = 0.24). Within-group changes indicated that between-group differences were mainly caused by a reduction in WAI in HOME. Of the seven items of WAI, item 2 (work ability in relation to the demands of the job) and item 5 (sickness absence during the past year) were improved in WORK compared with HOME (P < 0.05). Performing physical exercise together with colleagues at the workplace prevents deterioration of work ability among female healthcare workers. ClinicalTrials.gov NCT01921764 . Registered 10 August 2013.

Work Ability Index predicts application for disability pension after work-related medical rehabilitation for chronic back pain.

PubMed

Bethge, Matthias; Gutenbrunner, Christoph; Neuderth, Silke

2013-11-01

To determine whether the Work Ability Index (WAI), a short 7-item self-report questionnaire addressing issues of perceived disability, impairment, and expectations for resuming work, predicts application for disability pension, recommendations for further treatment, and other adverse work-related criteria in patients with chronic back pain after rehabilitation. Cohort study with 3-month follow-up. Seven inpatient rehabilitation centers. Patients (N=294; 168 women; mean age, 49.9y) with chronic back pain. The WAI was completed at the beginning of rehabilitation. All patients were treated according to the German rehabilitation guidelines for chronic back pain and work-related medical rehabilitation. Application for disability pension, as assessed by a postal questionnaire 3 months after discharge. Receiver operating characteristic curve analysis of the association between the WAI at baseline and subsequent application for disability pension revealed an area under the curve of .80 (95% confidence interval [CI], .62-.97). Youden index was highest when the WAI cutoff value was ≤20 points (sensitivity, 72.7%; specificity, 82.2%; total correct classification, 81.7%). After adjusting for age and sex, persons with a baseline WAI score of ≤20 points had 15.6 times (95% CI, 3.6-68.2) higher odds of subsequent application for disability pension, 4.9 times (95% CI, 1.5-16.8) higher odds of unemployment, and 6 times (95% CI, 2.4-15.2) higher odds of long-term sick leave at follow-up. The WAI could help rehabilitation professionals identify patients with back pain with a high risk of a subsequent application for disability pension. Copyright © 2013 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

Evidence for the stability of the West Antarctic Ice Sheet divide for 1.4 million years

PubMed Central

Hein, Andrew S.; Woodward, John; Marrero, Shasta M.; Dunning, Stuart A.; Steig, Eric J.; Freeman, Stewart P. H. T.; Stuart, Finlay M.; Winter, Kate; Westoby, Matthew J.; Sugden, David E.

2016-01-01

Past fluctuations of the West Antarctic Ice Sheet (WAIS) are of fundamental interest because of the possibility of WAIS collapse in the future and a consequent rise in global sea level. However, the configuration and stability of the ice sheet during past interglacial periods remains uncertain. Here we present geomorphological evidence and multiple cosmogenic nuclide data from the southern Ellsworth Mountains to suggest that the divide of the WAIS has fluctuated only modestly in location and thickness for at least the last 1.4 million years. Fluctuations during glacial–interglacial cycles appear superimposed on a long-term trajectory of ice-surface lowering relative to the mountains. This implies that as a minimum, a regional ice sheet centred on the Ellsworth-Whitmore uplands may have survived Pleistocene warm periods. If so, it constrains the WAIS contribution to global sea level rise during interglacials to about 3.3 m above present. PMID:26838462

Work ability index among healthcare personnel in a university hospital in Tehran, Iran.

PubMed

Mehrdad, R; Mazloumi, A; Arshi, S; Kazemi, Z

2016-03-09

Work ability is an important issue from a social point of view, as it is essential for workers health and welfare. This study aimed to determine work ability among healthcare personnel and to investigate its relationship with demographic and lifestyle-related factors. Data were collected using the Work Ability Index (WAI) questionnaire among 517 personnel of a hospital in Tehran, Iran. Findings showed a mean WAI of 40.3 (±5.2) for the study population. Work ability was significantly lower in the older personnel and higher for men. A significant correlation was observed between BMI and exercise activity and WAI score. Moreover, employees with experience of less than five years had significant higher work ability than those with 16-20 years of service. Considering the young study population, it seems the mean WAI is not as desirable. The use of lifestyle promoting programs, besides workplace interventions, can be an effective strategy to increase work ability among healthcare workers.

Subglacial Volcanism in West-Antarctica - A Geologic and Ice Dynamical Perspective

NASA Astrophysics Data System (ADS)

Vogel, S. W.; Tulaczyk, S.; Carter, S.; Renne, P.; Turrin, B. D.; Joughin, I.

2004-12-01

Subglacial volcanic eruptions may increase the contribution of the West-Antarctic Ice-Sheet (WAIS) to global sea-level rise in the near-future by enhancing basal melt water production and ice flow lubrication. Geophysical data have led scientists to believe that the ice sheet may be located over an extensive, young volcanic province containing ~1 million cubic kilometers of basalts (Behrendt, 1964; Behrendt et. al., 1991; 1995; 1998). While not all scientists may recognize this theory of widespread subglacial volcanism, so far no scientific paper has challenged its existence. Here we present the first geologic constraints on the presence/absence of widespread Late Cenozoic subglacial volcanism beneath the WAIS and investigate the potential influence of an individual subglacial volcano (Blankenship et. al., 1993) on the flow dynamic of WAIS. Properties of subglacial sediments indicate limited presence of subglacial volcanic rocks. Moreover, the only two basaltic pebbles, recovered from the region, are of Mesozoic-Paleozoic age (~100 to ~500 million years). While these findings reduce the potential for widespread near-future increases in ice discharge from WAIS due to eruptions of subglacial volcanoes, they do not rule out the presence of individual hot spots associated with volcanic centers beneath the WAIS. Fuel for the existence of a proposed volcano (Mt. Casertz) on the Whitmore Mountain Ross Sea Transitional Crust (WRT; Blankenship et. al., 1993), in the southern part of the WAIS, comes from thermo-dynamical modeling in comparison with observed ice velocities. Ice velocities (Joughin et. al., 1999; 2002) downstream of Mt. Casertz indicate significant basal sliding, where thermo-dynamical models suggest that the ice sheet is frozen to its base. Routing of basal melt water, produced in the vicinity of Mt. Casertz, may lubricate the ice base in parts of the WRT, thus enabling basal sliding and enhancing the discharge of ice in this sector of the WAIS. The only means to resolve any further questions on the existence of subglacial volcanism in West-Antarctica and its potential impact on the dynamic of the ice sheet, requires drilling into potential volcanic centers and the recovery of volcanic rocks for dating and geochemical analysis.

Late Oligocene glacimarine sedimentation of the central Ross Sea and implications for the evolution of the West Antarctic Ice Sheet

NASA Astrophysics Data System (ADS)

Kraus, C.; Mckay, R. M.; Naish, T.; Levy, R. H.; Kulhanek, D. K.

2015-12-01

Today the West Antarctic Ice Sheet (WAIS) is grounded mostly below sea level, making it sensitive to oceanic temperature and circulation changes. However, recent reconstructions of the Cenozoic bedrock topographic evolution of West Antarctica have suggested that the West Antarctic Ice Sheet (WAIS) may have first formed as a terrestrial ice sheet at the Eocene-Oligocene boundary (33 Ma), when there was up to 20% more land area in West Antarctica. At some point during the Oligocene or Miocene (23 - 5 Ma) vast areas of West Antarctica became an over-deepened marine-based continental shelf, as is observed today. The evolution of the WAIS through this transition is largely unconstrained, but as atmospheric CO2 fluctuated between 600 and 200 ppm over the past 34 Ma, determining the development of a marine-based WAIS is critical in the context of understanding the sensitivity of ice sheet systems to environmental change. Our research re-examines the sediment cores recovered from the central Ross Sea, a principal drainage area of the WAIS, at Deep Sea Drilling Project Site 270 (77°26.48'S, 178°30.19'W). These cores contain a glacimarine sequence of late Oligocene age (28 - 23.1 Ma). Sedimentological (visual core description, facies, grain size analysis), geochemical (x-ray fluorescence), geophysical (seismic) techniques, and physical properties (magnetic susceptibility) are used to construct a sedimentation model of this sequence, in order to track the late Oligocene evolution of the WAIS. The late Oligocene warming (25 - 23 Ma) is examined in detail because proximal Antarctic geological records of ice sheet extent, proxy environmental data, and atmospheric CO2 appear to be at odds with the composite δ18O record of global temperature and ice volume at this time. Moreover, our research provides insights into the sensitivity of marine-based ice sheets, and supports the hypothesis that they are unstable above a CO2 threshold of 400 ppm. Our preliminary results also indicate that the WAIS may have been responsive to orbital forcing during the late Oligocene.

Longitudinal associations between stressors and work ability in hospital workers.

PubMed

Carmen Martinez, Maria; da Silva Alexandre, Tiago; Dias de Oliveira Latorre, Maria do Rosario; Marina Fischer, Frida

This study sought to assess associations between work stressors and work ability in a cohort (2009-2012) of 498 hospital workers. Time-dependent variables associated with the Work Ability Index (WAI) were evaluated using general linear mixed models. Analyses included effects of individual and work characteristics. Except for work demands, the work stressors (job control, social support, effort-reward imbalance, overcommitment and work-related activities that cause pain/injury) were associated with WAI (p < 0.050) at intercept and in the time interaction. Daytime work and morning shift work were associated with decreased WAI (p < 0.010). Work stressors negatively affected work ability over time independently of other variables.

Factor Analysis of the WAIS and Twenty French-Kit Reference Tests.

ERIC Educational Resources Information Center

Ramsey, Philip H.

1979-01-01

The Wechsler Adult Intelligence Scale (WAIS) and 20 tests from the French Kit were administered to over 100 undergraduates. Analyses revealed ten factors: verbal comprehension, visualization, memory span, syllogistic reasoning, general reasoning, induction, mechanical knowledge, number facility, spatial orientation, and associative memory.…

Effects of Work-Related Stress on Work Ability Index among Iranian Workers.

PubMed

Gharibi, Vahid; Mokarami, Hamidreza; Taban, Abrahim; Yazdani Aval, Mohsen; Samimi, Kazem; Salesi, Mahmood

2016-03-01

Work Ability Index (WAI) is a well-known and valid self-report tool that has been widely used in various studies to identify and avoid early retirement and work-related disability. Nevertheless, very few studies have been carried out to evaluate work ability in Iran. We aimed to investigate the WAI and the effect of work-related stress on it among Iranian workers. A cross-sectional, descriptive and analytic study was carried out among 449 workers from five working sectors in three big cities of Iran. Work ability and work-related stress were measured using the Persian version of WAI and the Persian version of Health and Safety Executive Stress Indicator Tool. More than a third of the workers surveyed (34.70%) did not have an appropriate level of work ability (WAI < 37). There was a significant correlation between subscales of work-related stress and the mean score of WAI. Furthermore, the variables of body mass index, sleep quality, exercise activity, job tenure, and three subscales of work-related stress including demands, supervisor support, and role were significant predictors of WAI. According to the results of this study, the interventional programs must be focused on improving supervisors support, eliminating ambiguity and conflicts in the role of workers in their job and organization, reducing job demands, improving sleep quality, and increasing exercise activity.

Aerogeophysical evidence for active volcanism beneath the West Antarctic Ice Sheet

NASA Technical Reports Server (NTRS)

Blankenship, Donald D.; Bell, Robin E.; Hodge, Steven M.; Brozena, John M.; Behrendt, John C.

1993-01-01

Although it is widely understood that the collapse of the West Antarctic Ice Sheet (WAIS) would cause a global sea-level rise of 6 m, there continues to be considerable debate about the response of this ice sheet to climate change. The stability of the WAIS, which is characterized by a bed grounded well below sea level, may depend on geologically controlled conditions at the base, which are independent of climate. Ice streams moving up to 750 m/yr disperse material from the interior through to the oceans. As these ice streams tend to buffer the reservoir of slow-moving inland ice from exposure to oceanic degradation, understanding the ice-streaming process is important for evaluating WAIS stability. There is strong evidence that ice streams slide on a lubricating layer of water-saturated till. Development of this basal layer requires both water and easily eroded sediments. Active lithospheric extension may elevate regional heat flux, increase basal melting, and trigger ice streaming. If a geologically defined boundary with a sharp contrast in geothermal flux exists beneath the WAIS, ice streams may only be capable of operating as a buffer over a restricted region. Should ocean waters penetrate beyond this boundary, the ice-stream buffer would disappear, possibly triggering a collapse of the inland ice reservoir. Aerogeophysical evidence for active volcanism and elevated heat flux beneath the WAIS near the critical region where ice streaming begins is presented.

Investigation of the Relationship between Work Ability and Work-related Quality of Life in Nurses.

PubMed

Abbasi, Milad; Zakerian, Abolfazl; Akbarzade, Arash; Dinarvand, Nader; Ghaljahi, Maryam; Poursadeghiyan, Mohsen; Ebrahimi, Mohammad Hossein

2017-10-01

Work ability of nurses is an index of their job satisfaction and is a crucial factor in job quality and security. This study aimed to investigate the association between work ability and quality of working life and to determine the effective demographic and background variables, among nurses. The present study was conducted among nurses, working in educational hospitals under the supervision of Tehran University of Medical Sciences in 2014. Work Ability Index (WAI) and Work-related Quality of Life (WRQoL) were used. The mean WAI was significantly associated with total WRQoL score and the two of its sub-items including Stress at Work, and General Well-Being ( P -value=0.001). Moreover, the results showed a significant correlation between total WRQoL and WAI Subscales including mental resources ( P -value=0.001), number of current diseases ( P- value=0.02), and work ability in relation to the job demands ( P -value=0.04). The WRQoL and WAI showed significant associations with age and job experience ( P -value=0.001). The average score of WAI and WRQoL was statistically different among various working units ( P -value=0.001). Overall, results support the association between nurses work ability and WRQoL. Monitoring the WRQoL and work ability of employees would help organizations to know their status and take measures to ameliorate the working conditions.

Wideband acoustic immittance for assessing middle ear functioning for preterm neonates in the neonatal intensive care unit.

PubMed

Gouws, Nandel; Swanepoel, De Wet; De Jager, Leigh Biagio

2017-06-28

The primary aim of newborn hearing screening is to detect permanent hearing loss. Because otoacoustic emissions (OAEs) and automated auditory brainstem response (AABR) are sensitive to hearing loss, they are often used as screening tools. On the other hand, false-positive results are most often because of transient outer- and middle ear conditions. Wideband acoustic immittance (WAI), which includes physical measures known as reflectance and absorbance, has shown potential for accurate assessment of middle ear function in young infants. The main objective of this study was to determine the feasibility of WAI as a diagnostic tool for assessing middle ear functioning in preterm neonates in the neonatal intensive care unit (NICU) designed for premature and ill neonates. A further objective was to indicate the difference between the reflectance values of tones and click stimuli. Fifty-six at-risk neonates (30 male and 26 female), with a mean age at testing of 35.6 weeks (range: 32-37 weeks) and a standard deviation of 1.6 from three private hospitals, who passed both the distortion product otoacoustic emission (DPOAE) and AABR tests, were evaluated prior to discharge from the NICU. Neonates who presented with abnormal DPOAE and AABR results were excluded from the study. WAI was measured by using chirp and tone stimuli. In addition to reflectance, the reflectance area index (RAI) values were calculated. Both tone and chirp stimuli indicated high-power reflectance values below a frequency of 1.5 kHz. Median reflectance reached a minimum of 0.67 at 1 kHz - 2 kHz but increased to 0.7 below 1 kHz and 0.72 above 2 kHz for the tone stimuli. For chirp stimuli, the median reflectance reached a minimum of 0.51 at 1 kHz - 2 kHz but increased to 0.68 below 1 kHz and decreased to 0.5 above 2 kHz. A comparison between the present study and previous studies on WAI indicated a substantial variability across all frequency ranges. These WAI measurements conducted on at-risk preterm NICU neonates (mean age at testing: 35.6 weeks, range: 32-37 weeks) identified WAI patterns not previously reported in the literature. High reflective values were obtained across all frequency ranges. The age of the neonates when tested might have influenced the results. The neonates included in the present study were very young preterm neonates compared to the ages of neonates in previous studies. WAI measured in at-risk preterm neonates in the NICU was variable with environmental and internal noise influences. Transient conditions affecting the sound-conduction pathway might have influenced the results. Additional research is required to investigate WAI testing in ears with and without middle ear dysfunction. The findings of the current study imply that in preterm neonates it was not possible to determine the feasibility of WAI as a diagnostic tool to differentiate between ears with and without middle ear pathology.

Age Dedifferentiation Hypothesis: Evidence form the WAIS III.

ERIC Educational Resources Information Center

Juan-Espinosa, Manuel; Garcia, Luis F.; Escorial, Sergio; Rebollo, Irene; Colom, Roberto; Abad, Francisco J.

2002-01-01

Used the Spanish standardization of the Wechsler Adult Intelligence Scale III (WAIS III) (n=1,369) to test the age dedifferentiation hypothesis. Results show no changes in the percentage of variance accounted for by "g" and four group factors when restriction of range is controlled. Discusses an age indifferentation hypothesis. (SLD)

Education, Wechler's Full Scale IQ and "g."

ERIC Educational Resources Information Center

Colom, Roberto; Abad, Francisco J.; Garcia, Luis F.; Juan-Espinosa, Manuel

2002-01-01

Investigated whether average Full Scale IQ (FSIQ) differences can be attributed to "g" using the Spanish standardization sample of the Wechsler Adult Intelligence Scale III (WAIS III) (n=703 females and 666 men). Results support the conclusion that WAIS III FSIQ does not directly or exclusively measure "g" across the full range…

Test-Retest Gains in WAIS Scores after Four Retest Intervals.

ERIC Educational Resources Information Center

Catron, David W.; Thompson, Claudia C.

1979-01-01

To analyze the hypothesis that retest gain scores would decrease in a decelerating curve to zero-gain as the retest interval increased, male college students were administered the WAIS on two occasions with a retest at either 1 week, 2 months, or 4 months. (Author/SJL)

WAIS-IV Subtest Covariance Structure: Conceptual and Statistical Considerations

ERIC Educational Resources Information Center

Ward, L. Charles; Bergman, Maria A.; Hebert, Katina R.

2012-01-01

D. Wechsler (2008b) reported confirmatory factor analyses (CFAs) with standardization data (ages 16-69 years) for 10 core and 5 supplemental subtests from the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV). Analyses of the 15 subtests supported 4 hypothesized oblique factors (Verbal Comprehension, Working Memory, Perceptual Reasoning,…

Some Ethnic Cognitive Patterns.

ERIC Educational Resources Information Center

Curtis, Patricia Gelber

It was hypothesized that there are significant differences in intellectual patterns between black and white populations which can be demonstrated on the Wechsler Adult Intelligence Scale (WAIS). A one-way analysis of variance was performed on the subjects' scores on the WAIS subtests and the Verbal, Peformance and Full Scale IQ using the ethnic…

Brief Report: The Use of WAIS-III in Adults with HFA and Asperger Syndrome

PubMed Central

Scholte, Evert M.; van Berckelaer-Onnes, Ina A.

2007-01-01

The WAIS III was administered to 16 adults with high functioning autism (HFA) and 27 adults with Asperger syndrome. Differences between Verbal Intelligence (VIQ) and Performance Intelligence (PIQ) were not found. Processing Speed problems in people with HFA appeared. At the subtest level, the Asperger syndrome group performed weak on Digit Span. Comprehension and Block Design were relative strengths. In the HFA group, performance on Digit-Symbol Coding and Symbol Search was relatively poor. Strengths were found on Information and Matrix Reasoning. The results suggest that the VIQ-PIQ difference cannot distinguish between HFA and Asperger syndrome. WAIS III Factor Scale and Subtest patterning provides a more valid indicator. PMID:17879152

Discrepancy Score Reliabilities in the WAIS-IV Standardization Sample

ERIC Educational Resources Information Center

Glass, Laura A.; Ryan, Joseph J.; Charter, Richard A.

2010-01-01

In the present investigation, the authors provide internal consistency reliabilities for Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) subtest and Index discrepancy scores using the standardization sample as the data source. Reliabilities ranged from 0.55 to 0.88 for subtest discrepancy scores and 0.80 to 0.91 for Index discrepancy…

WAIS-R Verbal and Performance Profiles of Adolescents Referred for Atypical Learning Styles.

ERIC Educational Resources Information Center

Rush, Pamela; And Others

This study investigated Wechsler Adult Intelligence Scale-Revised (WAIS-R) profiles of deaf adolescents referred for academic difficulties. In addition, differences between referral deaf students and non-referral deaf peers were explored. The sample consisted of 28 severely-to-profoundly hearing impaired students enrolled in the School of…

Relationship of Education and IQ in the WAIS-R Standardization Sample.

ERIC Educational Resources Information Center

Matarazzo, Joseph D.; Herman, David O.

1984-01-01

Analyzed the total number of years of schooling completed against the Verbal IQ (VIQ), Performance IQ (PIQ), and Full Scale IQ (FSIQ) of the 1,880 individuals who were used to standardize the Wechsler Adult Intelligence Scale-Revised (WAIS-R). Analysis revealed a progressive increase in mean FSIQ with increasing education. (JAC)

Validity of the Working Alliance Inventory within Child Protection Services

ERIC Educational Resources Information Center

Killian, Michael; Forrester, Donald; Westlake, David; Antonopoulou, Paraskevi

2017-01-01

The Working Alliance Inventory remains a widely studied measure of quality of therapeutic relationships between the practitioner and client. No prior study has examined the psychometrics and validity of the Working Alliance Inventory-Short (WAI-S) in a sample of families, social workers, and trained observers within child protection services.…

Validating the Learning Disability Screening Questionnaire against the Weschler Adult Intelligence Scale, Fourth Edition

ERIC Educational Resources Information Center

McKenzie, Karen; Sharples, Phil; Murray, Aja L.

2015-01-01

The Learning Disability Screening Questionnaire (LDSQ), a brief screening tool for intellectual disability, was originally validated against the Weschler Adult Intelligence Scale, Third Edition (WAIS-III), which was superseded by the Weschler Adult Intelligence Scale, Fourth Edition (WAIS-IV) in the United Kingdom in 2010. This study examines the…

Material-specific retroactive interference effects of the Wechsler Adult Intelligence Scale-Fourth Edition on the Wechsler Memory Scale-Fourth Edition in a nonclinical sample.

PubMed

Ingram, Nicolette S; Diakoumakos, Jessica V; Sinclair, Erin R; Crowe, Simon F

2016-01-01

This study investigated proactive and retroactive interference effects between the Wechsler Memory Scale-Fourth Edition (WMS-IV) using the flexible approach, and the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV). One hundred and eighty nonclinical participants were assigned to a four (visual interference, verbal interference, visual and verbal interference, vs. no interference) by two (retroactive vs. proactive) between-subjects design. The administration order of the tests was counterbalanced (i.e., administration of the WAIS-IV prior to the WMS-IV, and the WAIS-IV administered during the delay interval of the WMS-IV). The WAIS-IV produced significant retroactive interference effects on the WMS-IV; however, no proactive interference effect was observed. The retroactive interference effect was dependent on material specificity. The results indicate that material presented within the delay of the WMS-IV can have a significant effect on subsequent delayed recall. Clinicians should carefully consider the effects associated with carry-over effects of these tests when using them in combination.

The effects of work-related and individual factors on the Work Ability Index: a systematic review.

PubMed

van den Berg, T I J; Elders, L A M; de Zwart, B C H; Burdorf, A

2009-04-01

This paper systematically reviews the scientific literature on the effects of individual and work-related factors on the Work Ability Index (WAI). Studies on work ability published from 1985 to 2006 were identified through a structured search in PubMed, and Web of Science. Studies were included if the WAI was used as measure of work ability and if quantitative information was presented on determinants of work ability. In total, 20 studies were included with 14 cross-sectional studies and six longitudinal studies. Factors associated with poor work ability, as defined by WAI, were lack of leisure-time vigorous physical activity, poor musculoskeletal capacity, older age, obesity, high mental work demands, lack of autonomy, poor physical work environment, and high physical work load. The WAI is associated with individual characteristics, lifestyle, demands at work, and physical condition. This multifactorial nature of work ability should be taken into account in health promotion programmes aimed at maintaining and promoting the participation of the labour force and improvement of the performance at work.

Psychometric qualities of a tetrad WAIS-III short form for use in individuals with mild to borderline intellectual disability.

PubMed

van Duijvenbode, Neomi; Didden, Robert; van den Hazel, Teunis; Engels, Rutger C M E

2016-01-01

To investigate the reliability and validity of a Wechsler Abbreviated Scale of Intelligence-based Wechsler Adult Intelligence Scale - third edition (WAIS-III) short form (SF) in a sample of individuals with mild to borderline intellectual disability (MBID) (N = 117; M(IQ) = 71.34; SD(IQ) = 8.00, range: 52-85). A full WAIS-III was administered as a standard procedure in the diagnostic process. The results indicate an excellent reliability (r = 0.96) and a strong, positive correlation with the full WAIS-III (r = 0.89). The SF correctly identified ID in general and the correct IQ category more specifically in the majority of cases (97.4% and 86.3% of cases, respectively). In addition, 82.1% of the full scale IQ (FSIQ) estimates fell within the 95% confidence interval of the original score. We conclude that the SF is a reliable and valid measure to estimate FSIQ. It can be used in clinical and research settings when global estimates of intelligence are sufficient.

Neuropsychological correlates of sustained attention in schizophrenia.

PubMed

Chen, E Y; Lam, L C; Chen, R Y; Nguyen, D G; Chan, C K; Wilkins, A J

1997-04-11

We employed a simple and relatively undemanding task of monotone counting for the assessment of sustained attention in schizophrenic patients. The monotone counting task has been validated neuropsychologically and is particularly sensitive to right prefrontal lesions. We compared the performance of schizophrenic patients with age- and education-matched controls. We then explored the extent to which a range of commonly employed neuropsychological tasks in schizophrenia research are related to attentional impairment as measured in this way. Monotone counting performance was found to be correlated with digit span (WAIS-R-HK), information (WAIS-R-HK), comprehension (WAIS-R-HK), logical memory (immediate recall) (Weschler Memory Scale, WMS), and visual reproduction (WMS). Multiple regression analysis also identified visual reproduction, digit span and comprehension as significant predictors of attention performance. In contrast, logical memory (delay recall) (WMS), similarity (WAIS-R-HK), semantic fluency, and Wisconsin Card Sorting Test (perseverative errors) were not correlated with attention. In addition, no significant correlation between sustained attention and symptoms was found. These findings are discussed in the context of a weakly modular cognitive system where attentional impairment may contribute selectively to a range of other cognitive deficits.

The reliability of multidimensional neuropsychological measures: from alpha to omega.

PubMed

Watkins, Marley W

To demonstrate that Coefficient omega, a model-based estimate, is more a more appropriate index of reliability than coefficient alpha for the multidimensional scales that are commonly employed by neuropsychologists. As an illustration, a structural model of an overarching general factor and four first-order factors for the WAIS-IV based on the standardization sample of 2200 participants was identified and omega coefficients were subsequently computed for WAIS-IV composite scores. Alpha coefficients were ≥ .90 and omega coefficients ranged from .75 to .88 for WAIS-IV factor index scores, indicating that the blend of general and group factor variance in each index score created a reliable multidimensional composite. However, the amalgam of variance from general and group factors did not allow the precision of Full Scale IQ (FSIQ) and factor index scores to be disentangled. In contrast, omega hierarchical coefficients were low for all four factor index scores (.10-.41), indicating that most of the reliable variance of each factor index score was due to the general intelligence factor. In contrast, the omega hierarchical coefficient for the FSIQ score was .84. Meaningful interpretation of WAIS-IV factor index scores as unambiguous indicators of group factors is imprecise, thereby fostering unreliable identification of neurocognitive strengths and weaknesses, whereas the WAIS-IV FSIQ score can be interpreted as a reliable measure of general intelligence. It was concluded that neuropsychologists should base their clinical decisions on reliable scores as indexed by coefficient omega.

Investigation of the Relationship between Work Ability and Work-related Quality of Life in Nurses

PubMed Central

ABBASI, Milad; ZAKERIAN, Abolfazl; AKBARZADE, Arash; DINARVAND, Nader; GHALJAHI, Maryam; POURSADEGHIYAN, Mohsen; EBRAHIMI, Mohammad Hossein

2017-01-01

Background: Work ability of nurses is an index of their job satisfaction and is a crucial factor in job quality and security. This study aimed to investigate the association between work ability and quality of working life and to determine the effective demographic and background variables, among nurses. Methods: The present study was conducted among nurses, working in educational hospitals under the supervision of Tehran University of Medical Sciences in 2014. Work Ability Index (WAI) and Work-related Quality of Life (WRQoL) were used. Results: The mean WAI was significantly associated with total WRQoL score and the two of its sub-items including Stress at Work, and General Well-Being (P-value=0.001). Moreover, the results showed a significant correlation between total WRQoL and WAI Subscales including mental resources (P-value=0.001), number of current diseases (P-value=0.02), and work ability in relation to the job demands (P-value=0.04). The WRQoL and WAI showed significant associations with age and job experience (P-value=0.001). The average score of WAI and WRQoL was statistically different among various working units (P-value=0.001). Conclusion: Overall, results support the association between nurses work ability and WRQoL. Monitoring the WRQoL and work ability of employees would help organizations to know their status and take measures to ameliorate the working conditions. PMID:29308385

Effect of subglacial volcanism on changes in the West Antarctic Ice Sheet

NASA Technical Reports Server (NTRS)

Behrendt, John C.

1993-01-01

Rapid changes in the West Antarctic Ice Sheet (WAIS) may affect future global sea-level changes. Alley and Whillans note that 'the water responsible for separating the glacier from its bed is produced by frictional dissipation and geothermal heat,' but assume that changes in geothermal flux would ordinarily be expected to have slower effects than glaciological parameters. I suggest that episodic subglacial volcanism and geothermal heating may have significantly greater effects on the WAIS than is generally appreciated. The WAIS flows through the active, largely asiesmic West Antarctic rift system (WS), which defines the sub-sea-level bed of the glacier. Various lines of evidence summarized in Behrendt et al. (1991) indicate high heat flow and shallow asthenosphere beneath the extended, weak lithosphere underlying the WS and the WAIS. Behrendt and Cooper suggest a possible synergistic relation between Cenozoic tectonism, episodic mountain uplift and volcanism in the West Antarctic rift system, and the waxing and waning of the Antarctic ice sheet beginning about earliest Oligocene time. A few active volcanoes and late-Cenozoic volcanic rocks are exposed throughout the WS along both flanks, and geophysical data suggest their presence beneath the WAIS. No part of the rift system can be considered inactive. I propose that subglacial volcanic eruptions and ice flow across areas of locally (episodically?) high heat flow--including volcanically active areas--should be considered possibly to have a forcing effect on the thermal regime resulting in increased melting at the base of the ice streams.

An examination of the Wechsler Adult Intelligence Scales, Fourth Edition (WAIS-IV) in individuals with complicated mild, moderate and Severe traumatic brain injury (TBI).

PubMed

Carlozzi, Noelle E; Kirsch, Ned L; Kisala, Pamela A; Tulsky, David S

2015-01-01

This study examined the clinical utility of the Wechsler Adult Intelligence Scales-Fourth Edition (WAIS-IV) in individuals with complicated mild, moderate or severe TBI. One hundred individuals with TBI (n = 35 complicated mild or moderate TBI; n = 65 severe TBI) and 100 control participants matched on key demographic variables from the WAIS-IV normative dataset completed the WAIS-IV. Univariate analyses indicated that participants with severe TBI had poorer performance than matched controls on all index scores and subtests (except Matrix Reasoning). Individuals with complicated mild/moderate TBI performed more poorly than controls on the Working Memory Index (WMI), Processing Speed Index (PSI), and Full Scale IQ (FSIQ), and on four subtests: the two processing speed subtests (SS, CD), two working memory subtests (AR, LN), and a perceptual reasoning subtest (BD). Participants with severe TBI had significantly lower scores than the complicated mild/moderate TBI on PSI, and on three subtests: the two processing speed subtests (SS and CD), and the new visual puzzles test. Effect sizes for index and subtest scores were generally small-to-moderate for the group with complicated mild/moderate and moderate-to-large for the group with severe TBI. PSI also showed good sensitivity and specificity for classifying individuals with severe TBI versus controls. Findings provide support for the clinical utility of the WAIS-IV in individuals with complicated mild, moderate, and severe TBI.

Exploratory and Higher-Order Factor Analyses of the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) Adolescent Subsample

ERIC Educational Resources Information Center

Canivez, Gary L.; Watkins, Marley W.

2010-01-01

The factor structure of the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV; Wechsler, 2008a) with the adolescent participants (ages 16-19 years; N = 400) in the standardization sample was assessed using exploratory factor analysis, multiple factor extraction criteria, and higher-order exploratory factor analyses. Results from…

Comparison of the K-BIT with Short Forms of the WAIS-R in a Neuropsychological Population.

ERIC Educational Resources Information Center

Eisenstein, Norman; Engelhart, Charles I.

1997-01-01

The Kaufman Brief Intelligence Test (K-BIT) (A. S. Kaufman and N. L. Kaufman, 1990) was compared with short forms of the Wechsler Adult Intelligence Scale--Revised (WAIS-R) using results from 64 referrals to a neuropsychology service. Advantages of each test are noted and their use discussed. (SLD)

WAIS Digit Span-Based Indicators of Malingered Neurocognitive Dysfunction: Classification Accuracy in Traumatic Brain Injury

ERIC Educational Resources Information Center

Heinly, Matthew T.; Greve, Kevin W.; Bianchini, Kevin J.; Love, Jeffrey M.; Brennan, Adrianne

2005-01-01

The present study determined specificity and sensitivity to malingered neurocognitive dysfunction (MND) in traumatic brain injury (TBI) for several Wechsler Adult Intelligence Scale (WAIS) Digit Span scores. TBI patients (n = 344) were categorized into one of five groups: no incentive, incentive only, suspect, probable MND, and definite MND.…

Concurrent Validity of Wechsler Adult Intelligence Scales-Third Edition Index Score Short Forms in the Canadian Standardization Sample

ERIC Educational Resources Information Center

Lange, Rael T.; Iverson, Grant L.

2008-01-01

This study evaluated the concurrent validity of estimated Wechsler Adult Intelligence Scales-Third Edition (WAIS-III) index scores using various one- and two-subtest combinations. Participants were the Canadian WAIS-III standardization sample. Using all possible one- and two-subtest combinations, an estimated Verbal Comprehension Index (VCI), an…

Mayo's Older Americans Normative Studies (MOANS): Factor Structure of a Core Battery.

ERIC Educational Resources Information Center

Smith, Glenn E.; And Others

1992-01-01

Using the Mayo Older Americans Normative Studies (MOANS) group (526 55-to 97-year-old adults), factor models were examined for the Wechsler Adult Intelligence Scale-Revised (WAIS-R); the Wechsler Memory Scale (WMS); and a core battery of the WAIS-R, the WMS, and the Rey Auditory-Verbal Learning Test. (SLD)

The Use of WAIS-III in Adults with HFA and Asperger Syndrome

ERIC Educational Resources Information Center

Spek, Antoinette A.; Scholte, Evert M.; van Berckelaer-Onnes, Ina A.

2008-01-01

The WAIS III was administered to 16 adults with high functioning autism (HFA) and 27 adults with Asperger syndrome. Differences between Verbal Intelligence (VIQ) and Performance Intelligence (PIQ) were not found. Processing Speed problems in people with HFA appeared. At the subtest level, the Asperger syndrome group performed weak on Digit Span.…

Entrapment of Ciliates at the Water-Air Interface

PubMed Central

Ferracci, Jonathan; Ueno, Hironori; Numayama-Tsuruta, Keiko; Imai, Yohsuke; Yamaguchi, Takami; Ishikawa, Takuji

2013-01-01

The importance of water-air interfaces (WAI) on microorganism activities has been recognized by many researchers. In this paper, we report a novel phenomenon: the entrapment of ciliates Tetrahymena at the WAI. We first characterized the behavior of cells at the interface and showed that the cells' swimming velocity was considerably reduced at the WAI. To verify the possible causes of the entrapment, we investigated the effects of positive chemotaxis for oxygen, negative geotaxis and surface properties. Even though the taxes were still effective, the entrapment phenomenon was not dependent on the physiological conditions, but was instead affected by the physical properties at the interface. This knowledge is useful for a better understanding of the physiology of microorganisms at interfaces in nature and in industry. PMID:24130692

Klippel-Trenaunay syndrome complicated by ascites and vaginal lymphatic drainage in adolescence: a case report.

PubMed

Scribner, Dennis R; Lara-Torre, Eduardo; Heineck, Robert J; Weiss, Patrice M

2012-12-01

Klippel-Trenaunay syndrome is a rare disease characterized by capillary malformationsand soft tissue and bony hypertrophy and atypical varicosities. Management of this syndrome is focused primarily on treatment of the complications that arise from these malformations. Ascites and lymphedema are two of the more common complications in these patients. A 15-year-old female with Klippel-Trenaunay syndrome presented with chylous ascites, vaginal drainage, and unilateral lower extremity lymphedema. Treatment included dilation, hysteroscopy and curettage, and laparoscopic evacuation of abdomino-pelvic ascites with resolution of symptoms for 32 months. Repeat laparoscopic drainage was successful and remains symptom free after 12 months. Vaginal drainage of chylous ascites is a rare complication from Klippel-Trenaunay syndrome and can be successfully managed by techniques to remove abdomino-pelvic ascites. Copyright © 2012 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

The assessment of virtual reality for human anatomy instruction

NASA Technical Reports Server (NTRS)

Benn, Karen P.

1994-01-01

This research project seeks to meet the objective of science training by developing, assessing, and validating virtual reality as a human anatomy training medium. In ideal situations, anatomic models, computer-based instruction, and cadaver dissection are utilized to augment the traditional methods of instruction. At many institutions, lack of financial resources limits anatomy instruction to textbooks and lectures. However, human anatomy is three dimensional, unlike the one dimensional depiction found in textbooks and the two dimensional depiction found on the computer. Virtual reality is a breakthrough technology that allows one to step through the computer screen into a three dimensional world. This technology offers many opportunities to enhance science education. Therefore, a virtual testing environment of the abdominopelvic region of a human cadaver was created to study the placement of body parts within the nine anatomical divisions of the abdominopelvic region and the four abdominal quadrants.

Norm comparisons of the Spanish-language and English-language WAIS-III: Implications for clinical assessment and test adaptation.

PubMed

Funes, Cynthia M; Rodriguez, Juventino Hernandez; Lopez, Steven Regeser

2016-12-01

This study provides a systematic comparison of the norms of 3 Spanish-language Wechsler Adult Intelligence Scales (WAIS-III) batteries from Mexico, Spain, and Puerto Rico, and the U.S. English-language WAIS-III battery. Specifically, we examined the performance of the 4 normative samples on 2 identical subtests (Digit Span and Digit Symbol-Coding) and 1 nearly identical subtest (Block Design). We found that across most age groups the means associated with the Spanish-language versions of the 3 subtests were lower than the means of the U.S. English-language version. In addition, we found that for most age ranges the Mexican subsamples scored lower than the Spanish subsamples. Lower educational levels of Mexicans and Spaniards compared to U.S. residents are consistent with the general pattern of findings. These results suggest that because of the different norms, applying any of the 3 Spanish-language versions of the WAIS-III generally risks underestimating deficits, and that applying the English-language WAIS-III norms risks overestimating deficits of Spanish-speaking adults. There were a few exceptions to these general patterns. For example, the Mexican subsample ages 70 years and above performed significantly better on the Digit Symbol and Block Design than did the U.S. and Spanish subsamples. Implications for the clinical assessment of U.S. Spanish-speaking Latinos and test adaptation are discussed with an eye toward improving the clinical care for this community. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

An Investigation of the General Abilities Index in a Group of Diagnostically Mixed Patients

ERIC Educational Resources Information Center

Harrison, Allyson G.; DeLisle, Michelle M.; Parker, Kevin C. H.

2008-01-01

The General Ability Index (GAI) was compared with Wechsler Adult Intelligence Scale-Third Edition (WAIS-III) Full Scale Intelligence Quotient (FSIQ) from the WAIS-III in data obtained from 381 adults assessed for reported learning or attention problems between 1998 and 2005. Not only did clients with more neurocognitively based disorders (i.e.,…

A Seven-Year Follow-Up of Intelligence Test Scores of Foster Grandparents

ERIC Educational Resources Information Center

Troll, Lillian E.; And Others

1976-01-01

After seven years, a group (N=32) of originally nonemployed poverty-level older people (over 60) now employed as foster grandparents were retested with the WAIS. Three subtest scores showed stability and Digit Span showed a statistically significant drop. Neither age nor initial level of health or WAIS scores was related to test-score changes over…

Graduate Student WAIS-III Scoring Accuracy Is a Function of Full Scale IQ and Complexity of Examiner Tasks

ERIC Educational Resources Information Center

Hopwood, Christopher J.; Richard, David C. S.

2005-01-01

Research on the Wechsler Adult Intelligence Scale-Revised and Wechsler Adult Intelligence Scale-Third Edition (WAIS-III) suggests that practicing clinical psychologists and graduate students make item-level scoring errors that affect IQ, index, and subtest scores. Studies have been limited in that Full-Scale IQ (FSIQ) and examiner administration,…

Brain Development Parameters and Intelligence in Chilean High School Graduates

ERIC Educational Resources Information Center

Ivanovic, Daniza M.; Leiva, Boris P.; Castro, Carmen G.; Olivares, Manuel G.; Jansana, Joan Manuel M.; Castro, Veronica G.; Almagia, Atilio Aldo F.; Toro, Triana D.; Urrutia, Maria Soledad C.; Miller, Patricio T.; Bosch, Enrique O.; Larrain, Cristian G.; Perez, Hernan T.

2004-01-01

The hypothesis that independently of sex, brain volume (BV) and head circumference (HC) are positively and significantly associated with intellectual quotient (IQ) was examined in a sample of 96 high school graduates of high [Wechsler Intelligence Scale for Adults--Revised (WAIS-R) is greater than 120] and low IQ (WAIS-R is less than 100) (1:1),…

Comparison of WAIS-III Short Forms for Measuring Index and Full-Scale Scores

ERIC Educational Resources Information Center

Girard, Todd A.; Axelrod, Bradley N.; Wilkins, Leanne K.

2010-01-01

This investigation assessed the ability of the Wechsler Adult Intelligence Scale-Third Edition (WAIS-III) short forms to estimate both index and IQ scores in a large, mixed clinical sample (N = 809). More specifically, a commonly used modification of Ward's seven-subtest short form (SF7-A), a recently proposed index-based SF7-C and eight-subtest…

A Comparison of WAIS-R and WAIS-III in the Lower IQ Range: Implications for Learning Disability Diagnosis

ERIC Educational Resources Information Center

Fitzgerald, Suzanne; Gray, Nicola S.; Snowden, Robert J.

2007-01-01

Background: Whether the Flynn effect (the increase in the populations' IQ over time) affects the IQ scores of people with learning disability or borderline learning disability remains unclear. The issue is important as the Flynn effect should alter the number of people eligible for health service resources. A comparison of the Wechsler Adult…

Test Review: D. Wechsler "Wechsler Adult Intelligence Scale" (4th ed.). San Antonio, TX--Psychological Corporation, 2008

ERIC Educational Resources Information Center

Climie, Emma A.; Rostad, Kristin

2011-01-01

This article presents a review of the "Wechsler Adult Intelligence Scale-Fourth Edition" (WAIS-IV), an individually administered measure of cognitive ability for individuals aged 16 years, 0 months to 90 years, 11 months. The WAIS-IV was designed with a number of specific goals including updated norms, increased user friendliness,…

Better Service through Data: Wai Sze (Lacey) Chan--Queens Borough Public Library, Jamaica, NY

ERIC Educational Resources Information Center

Library Journal, 2004

2004-01-01

The New Americans Program at Queens Borough Public Library (QBPL) is well known for the innovative collections and programs it provides to one of the nation's most diverse communities. What is less known is the rigorous analysis of demographic data that provides direction to the program. Wai Sze (Lacey) Chan uses demographics to create as complete…

Occupational stress perception and its potential impact on work ability.

PubMed

Yong, Mei; Nasterlack, Michael; Pluto, Rolf-Peter; Lang, Stefan; Oberlinner, Christoph

2013-01-01

To examine perceived stress across employees with different occupational status, to investigate the impact of stress on work ability and to derive conclusions regarding health promotion activities. A comprehensive survey combining questionnaire and medical examination was offered in one division in BASF Ludwigshafen. Among 867 voluntary participants, 653 returned complete questionnaires. The questions were directed at perception of safety at the workplace, self-rated health status, frequency of stress symptoms, unrealistic job demands, time pressure and maladjustment of work life balance. The outcome of interest was self-estimated health measured by the Work Ability Index (WAI). Occupational stressors were perceived differently across occupational status groups. Frontline operators had more health concerns due to workplace conditions, while professional and managerial staff reported higher frequencies of perceived tension, time pressure, and maladjustment of work life balance. After adjustment for occupational status, demographic and lifestyle factors, perceived stress was associated with a modest to strong decline in WAI scores. While perceived occupational stress had an apparent impact on WAI, and WAI has been demonstrated to be predictive of early retirement, more intensive and employee group-specific stress management interventions are being implemented beyond traditional strategies of routine occupational medical surveillance.

The Accuracy of Urinalysis in Predicting Intra-Abdominal Injury Following Blunt Traumas.

PubMed

Sabzghabaei, Anita; Shojaee, Majid; Safari, Saeed; Hatamabadi, Hamid Reza; Shirvani, Reza

2016-01-01

In cases of blunt abdominal traumas, predicting the possible intra-abdominal injuries is still a challenge for the physicians involved with these patients. Therefore, this study was designed, to evaluate the accuracy of urinalysis in predicting intra-abdominal injuries. Patients aged 15 to 65 years with blunt abdominal trauma who were admitted to emergency departments were enrolled. Abdominopelvic computed tomography (CT) scan with intravenous contrast and urinalysis were requested for all the included patients. Demographic data, trauma mechanism, the results of urinalysis, and the results of abdominopelvic CT scan were gathered. Finally, the correlation between the results of abdominopelvic CT scan, and urinalysis was determined. Urinalysis was considered positive in case of at least one positive value in gross appearance, blood in dipstick, or red blood cell count. 325 patients with blunt abdominal trauma were admitted to the emergency departments (83% male with the mean age of 32.63±17.48 years). Sensitivity, specificity, positive and negative predictive values, and positive and negative likelihood ratios of urinalysis, were 77.9% (95% CI: 69.6-84.4), 58.5% (95% CI: 51.2-65.5), 56% (95% CI: 48.5-63.3), 79.6% (95% CI: 71.8-85.7), 1.27% (95% CI: 1.30-1.57), and 0.25% (95% CI: 0.18-0.36), respectively. The diagnostic value of urinalysis in prediction of blunt traumatic intra-abdominal injuries is low and it seems that it should be considered as an adjuvant diagnostic tool, in conjunction with other sources such as clinical findings and imaging.

Correlation of abdominopelvic computed tomography with clinical manifestations in methamphetamine body stuffers.

PubMed

Bahrami-Motlagh, Hooman; Hassanian-Moghaddam, Hossein; Zamini, Hedieh; Zamani, Nasim; Gachkar, Latif

2018-02-01

Little is known about methamphetamine body stuffers and correlation of clinical manifestations with imaging studies. Current study was done to determine abdominopelvic computed tomography findings and clinical manifestations in methamphetamine body stuffers. In an IRB-approved routine data base study, demographic characteristics, clinical findings, and CT results of 70 methamphetamine body stuffers were retrieved. According to the clinical manifestations, the patients were categorized into either benign- or severe-outcome group. Also, they were determined to have positive or negative CT results. In the group with positive results, number and place of the baggies were determined, as well. Results of the CT were compared between the two groups. Almost 43% of the patients had positive abdominopelvic CT results. Mean density of the packs was 176.2 ± 152.7 Hounsfield unit. Based on the clinical grounds, 57% of the patients were in the benign- and 33% were in the severe-outcome group. In the benign group, 45% of the patients had positive CTs while in the severe-risk group, this was 40% (p > 0.05). Except variables defined as severe outcome (seizure, intubation, creatinine level, aspartate aminotransferase level, creatine phosphokinase and troponin level), agitation, on-arrival pulse rate, lactate dehydrogenase, bicarbonate, base excess, loss of consciousness and hospitalization period were correlating factors. But in regression analysis, we could not find a significant variable that prognosticate severe outcome. It seems that there is no relationship between the CT findings and clinical manifestations of the methamphetamine body stuffers. Severe outcomes may be observed even in the face of negative CTs.

Use of positive oral contrast agents in abdominopelvic computed tomography for blunt abdominal injury: meta-analysis and systematic review.

PubMed

Lee, Chau Hung; Haaland, Benjamin; Earnest, Arul; Tan, Cher Heng

2013-09-01

To determine whether positive oral contrast agents improve accuracy of abdominopelvic CT compared with no, neutral or negative oral contrast agent. Literature was searched for studies evaluating the diagnostic performance of abdominopelvic CT with positive oral contrast agents against imaging with no, neutral or negative oral contrast agent. Meta-analysis reviewed studies correlating CT findings of blunt abdominal injury with positive and without oral contrast agents against surgical, autopsy or clinical outcome allowing derivation of pooled sensitivity and specificity. Systematic review was performed on studies with common design and reference standard. Thirty-two studies were divided into two groups. Group 1 comprised 15 studies comparing CT with positive and without oral contrast agents. Meta-analysis of five studies from group 1 provided no difference in sensitivity or specificity between CT with positive or without oral contrast agents. Group 2 comprised 17 studies comparing CT with positive and neutral or negative oral contrast agents. Systematic review of 12 studies from group 2 indicated that neutral or negative oral contrasts were as effective as positive oral contrast agents for bowel visualisation. There is no difference in accuracy between CT performed with positive oral contrast agents or with no, neutral or negative oral contrast agent. • There is no difference in the accuracy of CT with or without oral contrast agent. • There is no difference in the accuracy of CT with Gastrografin or water. • Omission of oral contrast, utilising neutral or negative oral contrast agent saves time, costs and decreases risk of aspiration.

Intra-operative electron beam radiotherapy and abdomino-pelvic surgery for cancer: influence on immunological parameters.

PubMed

Bussières, E; Richaud, P; Gualde, N

1992-10-01

Evolution of some immunological parameters was observed during the first month in 20 patients with different abdomino-pelvic cancers who underwent surgery with intra-operative radiation therapy (IORT) (mean dose of 19.44 Gy, range 15, 25). Observed parameters before (DO-) and after procedure (DO+), on seventh (D7) and fourteenth (D14) days and fifth week (D30) were: lymphocyte count, lymphocyte subsets (CD19, CD3, CD4, CD8, CD56), natural killer (NK) activity, immunoglobulins, C3 and C4b fractions of complement, soluble receptor for interleukin 2 (sIL2-R). Results showed a decrease of circulating lymphocytes (DO-: 1189 +/- 168 cells/mm3; D7: 889 +/- 91; P = 0.011), of absolute number of CD3 lymphocytes (DO-: 785 +/- 114 cells/mm3; D7: 563 +/- 86; P = 0.025), of CD4 lymphocytes (DO-: 441 +/- 70 cells/mm3; DO+: 299 +/- 43; P = 0.013) and of CD8 lymphocytes (DO-:361 +/- 50 cells/mm3, D7:250 +/- 44; P = 0.006). All values returned towards preoperative levels by D30. Absolute number of NK cells was unchanged but NK activity was significantly diminished (effector target ratio 5:1 DO-:33 +/- 5%; DO+:44 +/- 7%; D7:18 +/- 3%; D14:21 +/- 4%; D30:25 +/- 4%). sIL2-R was significantly enhanced from D7 to D30. All these impairments are moderate and these observations provide some evidence of satisfactory tolerance to IORT for abdomino-pelvic cancers during the immediate postoperative period.

A seven-year follow-up of intelligence test scores of foster grandparents.

PubMed

Troll, L E; Saltz, R; Dunin-Markiewicz, A

1976-09-01

After 7 years, a group of originally nonemployed poverty-level older people (over 60) who had been employed as foster grandparents were retested with the WAIS. Four WAIS subtests - Vocabulary Similarities, Digit Span, and Block Design - were employed. Of the original group of 39, complete data were available for 28; 18 of these were still working on the project, and the other 10 had dropped out. Dropouts as a group tested lower originally and also showed more deterioration in functional health ratings over time. For the total group of 32 foster grandparents, three subtest scores showed stability over the 7 years. Only Digit Span showed a statistically significant drop. Neither age nor the initial level of health or WAIS scores was related to test-score changes over time.

Reliability and validity of the Spanish Language Wechsler Adult Intelligence Scale (3rd Edition) in a sample of American, urban, Spanish-speaking Hispanics.

PubMed

Renteria, Laura; Li, Susan Tinsley; Pliskin, Neil H

2008-05-01

The utility of the Spanish WAIS-III was investigated by examining its reliability and validity among 100 Spanish-speaking participants. Results indicated that the internal consistency of the subtests was satisfactory, but inadequate for Letter Number Sequencing. Criterion validity was adequate. Convergent and discriminant validity results were generally similar to the North American normative sample. Paired sample t-tests suggested that the WAIS-III may underestimate ability when compared to the criterion measures that were utilized to assess validity. This study provides support for the use of the Spanish WAIS-III in urban Hispanic populations, but also suggests that caution be used when administering specific subtests, due to the nature of the Latin America alphabet and potential test bias.

Factor structure of the Norwegian version of the WAIS-III in a clinical sample: the arithmetic problem.

PubMed

Egeland, Jens; Bosnes, Ole; Johansen, Hans

2009-09-01

Confirmatory Factor Analyses (CFA) of the Wechsler Adult Intelligence Scale-III (WAIS-III) lend partial support to the four-factor model proposed in the test manual. However, the Arithmetic subtest has been especially difficult to allocate to one factor. Using the new Norwegian WAIS-III version, we tested factor models differing in the number of factors and in the placement of the Arithmetic subtest in a mixed clinical sample (n = 272). Only the four-factor solutions had adequate goodness-of-fit values. Allowing Arithmetic to load on both the Verbal Comprehension and Working Memory factors provided a more parsimonious solution compared to considering the subtest only as a measure of Working Memory. Effects of education were particularly high for both the Verbal Comprehension tests and Arithmetic.

Polycystic ovary syndrome in a virilised, premenarcheal girl.

PubMed

Clarke, C F; Piesowicz, A T; Edmonds, K; Grant, D

1989-09-01

A premenarcheal girl aged 12 years presented with an abdominopelvic mass and virilisation. A large ovarian cyst was removed at laparotomy. A histological diagnosis of polycystic ovarian syndrome was made, with no evidence of an associated masculinising tumour.

A Survey of Pediatric CT Protocols and Radiation Doses in South Korean Hospitals to Optimize the Radiation Dose for Pediatric CT Scanning

PubMed Central

Hwang, Jae-Yeon; Do, Kyung-Hyun; Yang, Dong Hyun; Cho, Young Ah; Yoon, Hye-Kyung; Lee, Jin Seong; Koo, Hyun Jung

2015-01-01

Abstract Children are at greater risk of radiation exposure than adults because the rapidly dividing cells of children tend to be more radiosensitive and they have a longer expected life time in which to develop potential radiation injury. Some studies have surveyed computed tomography (CT) radiation doses and several studies have established diagnostic reference levels according to patient age or body size; however, no survey of CT radiation doses with a large number of patients has yet been carried out in South Korea. The aim of the present study was to investigate the radiation dose in pediatric CT examinations performed throughout South Korea. From 512 CT (222 brain CT, 105 chest CT, and 185 abdominopelvic CT) scans that were referred to our tertiary hospital, a dose report sheet was available for retrospective analysis of CT scan protocols and dose, including the volumetric CT dose index (CTDIvol), dose-length product (DLP), effective dose, and size-specific dose estimates (SSDE). At 55.2%, multiphase CT was the most frequently performed protocol for abdominopelvic CT. Tube current modulation was applied most often in abdominopelvic CT and chest CT, accounting for 70.1% and 62.7%, respectively. Regarding the CT dose, the interquartile ranges of the CTDIvol were 11.1 to 22.5 (newborns), 16.6 to 39.1 (≤1 year), 14.6 to 41.7 (2–5 years), 23.5 to 44.1 (6–10 years), and 31.4 to 55.3 (≤15 years) for brain CT; 1.3 to 5.7 (≤1 year), 3.9 to 6.8 (2–5 years), 3.9 to 9.3 (6–10 years), and 7.7 to 13.8 (≤15 years) for chest CT; and 4.0 to 7.5 (≤1 year), 4.2 to 8.9 (2–5 years), 5.7 to 12.4 (6–10 years), and 7.6 to 16.6 (≤15 years) for abdominopelvic CT. The SSDE and CTDIvol were well correlated for patients <5 years old, whereas the CTDIvol was lower in patients ≥6 years old. Our study describes the various parameters and dosimetry metrics of pediatric CT in South Korea. The CTDIvol, DLP, and effective dose were generally lower than in German and UK surveys, except in certain age groups. PMID:26683922

Volcanic rocks and subglacial volcanism beneath the West Antarctic Ice Sheet in the West Antarctic Rift System, (WAIS) from aeromagnetic and radar ice sounding - Thiel Subglacial Volcano as possible source of the ash layer in the WAISCORE

NASA Astrophysics Data System (ADS)

Behrendt, J. C.

2012-12-01

Radar ice sounding and aeromagnetic surveys reported over the West Antarctic Ice Sheet (WAIS) have been interpreted as evidence of subglacial volcanic eruptions over a very extensive area (>500,000 km2 ) of the volcanically active West Antarctic rift system interpreted as caused by subglacial volcanic rocks. Several active volcanoes have shown evidence of eruption through the WAIS and several other active volcanoes are present beneath the WAIS reported from radar and aeromagnetic data. Five-kilometer spaced coincident aeromagnetic and radar ice sounding surveys since 1990 provide three dimensional characterization of the magnetic field and bed topography beneath the ice sheet. These 5-50-km-width, semicircular magnetic anomalies range from 100->1000 nT as observed ~1 km over the 2-3 km thick ice have been interpreted as evidence of subglacial eruptions. Comparison of a carefully selected subset of ~400 of the >1000 high-amplitude anomalies in the CWA survey having topographic expression at the glacier bed, showed >80% had less than 200-m relief. About 18 high-amplitude subglacial magnetic sources also have high topography and bed relief (>600 m) interpreted as subaerially erupted volcanic peaks when the WAIS was absent, whose competent lava flows protected their edifices from erosion. All of these would have high elevation above sea-level, were the ice removed and glacial rebound to have occurred. Nine of these subaerially erupted volcanoes are concentrated in the WAIS divide area. Behrendt et al., 1998 interpreted a circular ring of positive magnetic anomalies overlying the WAIS divide as caused by a volcanic caldera. The area is characterized by high elevation bed topography. The negative regional magnetic anomaly surrounding the caldera anomalies was interpreted as the result of a shallow Curie isotherm. High heat flow inferred from temperature logging in the WAISCORE (G. Clow 2012, personal communication; Conway, 2011) and a prominent volcanic ash layer in the core (Dunbar, 2011) are consistent with the magnetic data. A prominent subaerially-erupted subglacial volcano, here named Mt Thiel, about 100 km distant to the NE, at approximately 78o 25' S, 111o 20' W, may be the source of the ash layer. This peak is characterized by a ~400-nT positive magnetic anomaly which Behrendt el, 2004, modeled as having apparent susceptibility contrasts of .034 and .15 SI. From its appearance (and the moat surrounding it), Mt. Thiel has subsided somewhat since initial eruption as is the case for Mt. Erebus and the Hawaiian Island chain. I suggest that Mt Thiel, about 100 km distance from the WAISCORE, may be the source of the ash layer. The present rapid changes in the WAIS resulting from global warming, could be accelerated by subglacial volcanism

Size-specific dose estimate (SSDE) provides a simple method to calculate organ dose for pediatric CT examinations

PubMed Central

Moore, Bria M.; Brady, Samuel L.; Mirro, Amy E.; Kaufman, Robert A.

2014-01-01

Purpose: To investigate the correlation of size-specific dose estimate (SSDE) with absorbed organ dose, and to develop a simple methodology for estimating patient organ dose in a pediatric population (5–55 kg). Methods: Four physical anthropomorphic phantoms representing a range of pediatric body habitus were scanned with metal oxide semiconductor field effect transistor (MOSFET) dosimeters placed at 23 organ locations to determine absolute organ dose. Phantom absolute organ dose was divided by phantom SSDE to determine correlation between organ dose and SSDE. Organ dose correlation factors (\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{upgreek} \\usepackage{mathrsfs} \\setlength{\\oddsidemargin}{-69pt} \\begin{document} }{}${\\rm CF}_{{\\rm SSDE}}^{{\\rm organ}}$\\end{document} CF SSDE organ ) were then multiplied by patient-specific SSDE to estimate patient organ dose. The \\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{upgreek} \\usepackage{mathrsfs} \\setlength{\\oddsidemargin}{-69pt} \\begin{document} }{}${\\rm CF}_{{\\rm SSDE}}^{{\\rm organ}}$\\end{document} CF SSDE organ were used to retrospectively estimate individual organ doses from 352 chest and 241 abdominopelvic pediatric CT examinations, where mean patient weight was 22 kg ± 15 (range 5–55 kg), and mean patient age was 6 yrs ± 5 (range 4 months to 23 yrs). Patient organ dose estimates were compared to published pediatric Monte Carlo study results. Results: Phantom effective diameters were matched with patient population effective diameters to within 4 cm; thus, showing appropriate scalability of the phantoms across the entire pediatric population in this study. Individual\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{upgreek} \\usepackage{mathrsfs} \\setlength{\\oddsidemargin}{-69pt} \\begin{document} }{}${\\rm CF}_{{\\rm SSDE}}^{{\\rm organ}}$\\end{document} CF SSDE organ were determined for a total of 23 organs in the chest and abdominopelvic region across nine weight subcategories. For organs fully covered by the scan volume, correlation in the chest (average 1.1; range 0.7–1.4) and abdominopelvic region (average 0.9; range 0.7–1.3) was near unity. For organ/tissue that extended beyond the scan volume (i.e., skin, bone marrow, and bone surface), correlation was determined to be poor (average 0.3; range: 0.1–0.4) for both the chest and abdominopelvic regions, respectively. A means to estimate patient organ dose was demonstrated. Calculated patient organ dose, using patient SSDE and \\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{upgreek} \\usepackage{mathrsfs} \\setlength{\\oddsidemargin}{-69pt} \\begin{document} }{}${\\rm CF}_{{\\rm SSDE}}^{{\\rm organ}}$\\end{document} CF SSDE organ , was compared to previously published pediatric patient doses that accounted for patient size in their dose calculation, and was found to agree in the chest to better than an average of 5% (27.6/26.2) and in the abdominopelvic region to better than 2% (73.4/75.0). Conclusions: For organs fully covered within the scan volume, the average correlation of SSDE and organ absolute dose was found to be better than ±10%. In addition, this study provides a complete list of organ dose correlation factors (\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{upgreek} \\usepackage{mathrsfs} \\setlength{\\oddsidemargin}{-69pt} \\begin{document} }{}${\\rm CF}_{{\\rm SSDE}}^{{\\rm organ}}$\\end{document} CF SSDE organ ) for the chest and abdominopelvic regions, and describes a simple methodology to estimate individual pediatric patient organ dose based on patient SSDE. PMID:24989395

WAIS-IV and WISC-IV Structural Validity: Alternate Methods, Alternate Results. Commentary on Weiss et al. (2013a) and Weiss et al. (2013b)

ERIC Educational Resources Information Center

Canivez, Gary L.; Kush, Joseph C.

2013-01-01

Weiss, Keith, Zhu, and Chen (2013a) and Weiss, Keith, Zhu, and Chen (2013b), this issue, report examinations of the factor structure of the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) and Wechsler Intelligence Scale for Children-Fourth Edition (WISC-IV), respectively; comparing Wechsler Hierarchical Model (W-HM) and…

Cognitive Profiles of Adults with Asperger's Disorder, High-Functioning Autism, and Pervasive Developmental Disorder Not Otherwise Specified Based on the WAIS-III

ERIC Educational Resources Information Center

Kanai, Chieko; Tani, Masayuki; Hashimoto, Ryuichiro; Yamada, Takashi; Ota, Haruhisa; Watanabe, Hiromi; Iwanami, Akira; Kato, Nobumasa

2012-01-01

Little is known about the cognitive profiles of high-functioning Pervasive Developmental Disorders (PDD) in adults based on the Wechsler Intelligence Scale III (WAIS-III). We examined cognitive profiles of adults with no intellectual disability (IQ greater than 70), and in adults with Asperger's disorder (AS; n = 47), high-functioning autism (HFA;…

Malingering in Toxic Exposure. Classification Accuracy of Reliable Digit Span and WAIS-III Digit Span Scaled Scores

ERIC Educational Resources Information Center

Greve, Kevin W.; Springer, Steven; Bianchini, Kevin J.; Black, F. William; Heinly, Matthew T.; Love, Jeffrey M.; Swift, Douglas A.; Ciota, Megan A.

2007-01-01

This study examined the sensitivity and false-positive error rate of reliable digit span (RDS) and the WAIS-III Digit Span (DS) scaled score in persons alleging toxic exposure and determined whether error rates differed from published rates in traumatic brain injury (TBI) and chronic pain (CP). Data were obtained from the files of 123 persons…

The Distribution of Scaled Scores and Possible Floor Effects on the WISC-III and WAIS-III

ERIC Educational Resources Information Center

Whitaker, Simon; Wood, Christopher

2008-01-01

Objective: It has been suggested that, as the Wechsler Adult Intelligence Scale-Third Edition (WAIS-III) and the Wechsler Intelligence Scale for Children-Third Edition (WISC-III) give a scaled score of one even if a client scores a raw score of zero, these assessments may have a hidden floor effect at low IQ levels. The study looked for…

Predicting long-term absenteeism from work in construction industry: a longitudinal study.

PubMed

Hoonakker, Peter; van Duivenbooden, Cor

2012-01-01

In this study we examine whether the Work Ability Index (WAI) has additional value in predicting long-term absenteeism in construction industry. Results of the study show that the WAI has additional value in predicting absenteeism, but that the amount of explained variance is low. This is partly due to the definition of absenteeism in The Netherlands, where this study took place.

Neuropsychological factors related to returning to work in patients with higher brain dysfunction.

PubMed

Kai, Akiko; Hashimoto, Manabu; Okazaki, Tetsuya; Hachisuka, Kenji

2008-12-01

We conducted neuropsychological tests of patients with higher brain dysfunction to examine the characteristics of barriers to employment. We tested 92 patients with higher brain dysfunction (average age of 36.3 +/- 13.8 years old, ranging between 16 and 63 years old, with an average post-injury period of 35.6 +/- 67.8 months) who were hospitalized at the university hospital between February 2002 and June 2007 for further neuropsychological evaluation, conducting the Wechsler Adult Intelligence Scale-Revised (WAIS-R), Wechsler Memory Scale-Revised (WMS-R), the Rivermead Behavioral Memory Test (RBMT), Frontal Assessment Battery (FAB) and Behavioral Assessment of Dysexecutive Syndrome (BADS). The outcomes after discharge were classified between competitive employment, sheltered employment and non-employment, and the three groups were compared using one-way analysis of variance and the Scheffe test. The WAIS-R subtests were mutually compared based on the standard values of significant differences described in the WAIS-R manual. Verbal performance and full scale Intelligence Quotient (IQ) of WAIS-R were 87.7 +/- 15.6 (mean +/- standard deviation), 78.5 +/- 18.1 and 81.0 +/- 17.2, respectively, and verbal memory, visual memory, general memory, attention/concentration and delayed recall were 74.6 +/- 20.0, 76.6 +/- 21.4, 72.0 +/- 20.4, 89.0 +/- 16.5 and 65.2 +/- 20.8, respectively. The competitive employment group showed significantly higher scores in performance IQ and full IQ on the WAIS-R and verbal memory, visual memory, general memory and delayed recall on the WMS-R and RBMT than the non-employment group. The sheltered employment group showed a significantly higher score in delayed recall than the non-employment group. No difference was observed in the FAB or BADS between the three groups. In the subtests of the WAIS-R, the score for Digit Symbol-Coding was significantly lower than almost all the other subtests. For patients with higher brain dysfunction, IQ (full scale IQ > 53.2) and memory (general memory > 74.1) are important indicators in returning to work under the conditions of competitive employment.

Is the work ability index useful to evaluate absence days in ankylosing spondylitis patients? A cross-sectional study

PubMed Central

Meyer, Katharina; Niedermann, Karin; Tschopp, Alois; Klipstein, Andreas

2013-01-01

Background The work incapacity of ankylosing spondylitis (AS) ranges between 3% and 50% in Europe. In many countries, work incapacity is difficult to quantify. The work ability index (WAI) is applied to measure the work ability in workers, but it is not well investigated in patients. Aims To investigate the work incapacity in terms of absence days in patients with AS and to evaluate whether the WAI reflects the absence from work. Hypothesis Absence days can be estimated based on the WAI and other variables. Design Cross-sectional design. Setting In a secondary care centre in Switzerland, the WAI and a questionnaire about work absence were administered in AS patients prior to cardiovascular training. The number of absence days was collected retrospectively. The absence days were estimated using a two-part regression model. Participants 92 AS patients (58 men (63%)). Inclusion criteria: AS diagnosis, ability to cycle, age between 18 and 65 years. Exclusion criteria: severe heart disease. Primary and secondary outcome measures Absence days. Results Of the 92 patients, 14 received a disability pension and 78 were in the working process. The median absence days per year of the 78 patients due to AS alone and including other reasons was 0 days (IQR 0–12.3) and 2.5 days (IQR 0–19), respectively. The WAI score (regression coefficient=−4.66 (p<0.001, CI −6.1 to −3.2), ‘getting a disability pension’ (regression coefficient=−106.8 (p<0.001, 95% CI −141.6 to −72.0) and other not significant variables explained 70% of the variance in absence days (p<0.001), and therefore may estimate the number of absence days. Conclusions Absences in our sample of AS patients were equal to pan-European countries. In groups of AS patients, the WAI and other variables are valid to estimate absence days with the help of a two-part regression model. PMID:23524041

Polycystic ovary syndrome in a virilised, premenarcheal girl.

PubMed Central

Clarke, C F; Piesowicz, A T; Edmonds, K; Grant, D

1989-01-01

A premenarcheal girl aged 12 years presented with an abdominopelvic mass and virilisation. A large ovarian cyst was removed at laparotomy. A histological diagnosis of polycystic ovarian syndrome was made, with no evidence of an associated masculinising tumour. PMID:2817952

Cognitive impairment in systemic lupus erythematosus women with elevated autoantibodies and normal single photon emission computerized tomography.

PubMed

Peretti, Charles-Siegfried; Peretti, Charles Roger; Kozora, Elizabeth; Papathanassiou, Dimitri; Chouinard, Virginie-Anne; Chouinard, Guy

2012-01-01

Systemic lupus erythematosus (SLE) is known to induce psychiatric disorders, from psychoses to maladaptive coping. Brain autoantibodies were proposed to explain SLE neuropsychiatric disorders and found to be elevated before the onset of clinical symptoms. We assessed cognition in Caucasian SLE women with elevated autoantibodies without overt neuropsychiatric syndromes, in conjunction with single photon emission computerized tomography (SPECT). 31 women meeting SLE criteria of the American College of Rheumatology (ACR) were included. Patients who met the ACR neuropsychiatric definition were excluded. Matched controls were 23 healthy women from the Champagne-Ardenne region, France. Participants completed neuropsychological and autoantibodies measurements, and 19 completed SPECT. 61% (19/31) of women with SLE and 53% (9/17) of those with normal SPECT had significant global cognitive impairment defined as 4 T-scores <40 in cognitive tests, compared to 0% (0/23) of controls. SLE women also had significantly greater cognitive dysfunction (mean T-score) on the Wechsler Adult Intelligence Scale (WAIS) visual backspan, Trail Making Test A and B, WAIS Digit Symbol Substitution Test and Stroop Interference, compared to controls. Elevated antinuclear antibody correlated with impairment in the WAIS visual span, WAIS visual backspan, and cancellation task; elevated anti-double-stranded DNA antibody and anticardiolipin correlated respectively with impairment in the Trail Making Test A and WAIS auditive backspan. Two SLE women had abnormal SPECT. A high prevalence of cognitive deficits was found in Caucasian SLE women compared to normal women, which included impairment in cognitive domains important for daily activities. Elevated autoantibodies tended to correlate with cognitive dysfunction. Copyright © 2012 S. Karger AG, Basel.

WAIS-IV Seven-Subtest Short Form: Validity and Clinical Use in Schizophrenia.

PubMed

Bulzacka, Ewa; Meyers, John E; Boyer, Laurent; Le Gloahec, Tifenn; Fond, Guillaume; Szöke, Andrei; Leboyer, Marion; Schürhoff, Franck

2016-09-01

This study assesses the psychometric properties of Ward's seven-subtest short form (SF) for WAIS-IV in a sample of adults with schizophrenia (SZ) and schizoaffective disorder. Seventy patients diagnosed with schizophrenia or schizoaffective disorder were administered the full version of the WAIS-IV. Four different versions of the Ward's SF were then calculated. The subtests used were: Similarities, Digit Span, Arithmetic, Information, Coding, Picture Completion, and Block Design (BD version) or Matrix Reasoning (MR version). Prorated and regression-based formulae were assessed for each version. The actual and estimated factorial indexes reflected the typical pattern observed in schizophrenia. The four SFs correlated significantly with their full-version counterparts, but the Perceptual Reasoning Index (PRI) correlated below the acceptance threshold for all four versions. The regression-derived estimates showed larger differences compared to the full form. The four forms revealed comparable but generally low clinical category agreement rates for factor indexes. All SFs showed an acceptable reliability, but they were not correlated with clinical outcomes. The WAIS-IV SF offers a good estimate of WAIS-IV intelligence quotient, which is consistent with previous results. Although the overall scores are comparable between the four versions, the prorated forms provided a better estimation of almost all indexes. MR can be used as an alternative for BD without substantially changing the psychometric properties of the SF. However, we recommend a cautious use of these abbreviated forms when it is necessary to estimate the factor index scores, especially PRI, and Processing Speed Index. © The Author 2016. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

A cross-cultural comparison between South African and British students on the Wechsler Adult Intelligence Scales Third Edition (WAIS-III).

PubMed

Cockcroft, Kate; Alloway, Tracy; Copello, Evan; Milligan, Robyn

2015-01-01

There is debate regarding the appropriate use of Western cognitive measures with individuals from very diverse backgrounds to that of the norm population. Given the dated research in this area and the considerable socio-economic changes that South Africa has witnessed over the past 20 years, this paper reports on the use of the Wechsler Adult Intelligence Scale Third Edition (WAIS-III), the most commonly used measure of intelligence, with an English second language, multilingual, low socio-economic group of black, South African university students. Their performance on the WAIS-III was compared to that of a predominantly white, British, monolingual, higher socio-economic group. A multi-group confirmatory factor analysis showed that the WAIS-III lacks measurement invariance between the two groups, suggesting that it may be tapping different constructs in each group. The UK group significantly outperformed the SA group on the knowledge-based verbal, and some non-verbal subtests, while the SA group performed significantly better on measures of Processing Speed (PS). The groups did not differ significantly on the Matrix Reasoning subtest and on those working memory subtests with minimal reliance on language, which appear to be the least culturally biased. Group differences were investigated further in a set of principal components analyses, which revealed that the WAIS-III scores loaded differently for the UK and SA groups. While the SA group appeared to treat the PS subtests differently to those measuring perceptual organization and non-verbal reasoning, the UK group seemed to approach all of these subtests similarly. These results have important implications for the cognitive assessment of individuals from culturally, linguistically, and socio-economically diverse circumstances.

Internet-based wide area measurement applications in deregulated power systems

NASA Astrophysics Data System (ADS)

Khatib, Abdel-Rahman Amin

Since the deregulation of power systems was started in 1989 in the UK, many countries have been motivated to undergo deregulation. The United State started deregulation in the energy sector in California back in 1996. Since that time many other states have also started the deregulation procedures in different utilities. Most of the deregulation market in the United States now is in the wholesale market area, however, the retail market is still undergoing changes. Deregulation has many impacts on power system network operation and control. The number of power transactions among the utilities has increased and many Independent Power Producers (IPPs) now have a rich market for competition especially in the green power market. The Federal Energy Regulatory Commission (FERC) called upon utilities to develop the Regional Transmission Organization (RTO). The RTO is a step toward the national transmission grid. RTO is an independent entity that will operate the transmission system in a large region. The main goal of forming RTOs is to increase the operation efficiency of the power network under the impact of the deregulated market. The objective of this work is to study Internet based Wide Area Information Sharing (WAIS) applications in the deregulated power system. The study is the first step toward building a national transmission grid picture using information sharing among utilities. Two main topics are covered as applications for the WAIS in the deregulated power system, state estimation and Total Transfer Capability (TTC) calculations. As a first step for building this national transmission grid picture, WAIS and the level of information sharing of the state estimation calculations have been discussed. WAIS impacts to the TTC calculations are also covered. A new technique to update the TTC using on line measurements based on WAIS created by sharing state estimation is presented.

West Antarctic Ice Sheet Initiative. Volume 1: Science and Implementation Plan

NASA Technical Reports Server (NTRS)

Bindschadler, Robert A. (Editor)

1990-01-01

The Science and Implementation Plan of the West Antarctic Ice Sheet Initiative (WAIS) is described. The goal of this initiative is the prediction of the future behavior of this ice sheet and an assessment of its potential to collapse, rapidly raising global sea level. The multidisciplinary nature of WAIS reflects the complexity of the polar ice sheet environment. The project builds upon past and current polar studies in many fields and meshes with future programs of both the U.S. and other countries. Important tasks in each discipline are described and a coordinated schedule by which the majority of these tasks can be accomplished in 5 years is presented. The companion report (Volume 2) contains seven discipline review papers on the state of knowledge of Antarctica and opinions on how that knowledge must be increased to attain the WAIS goal.

The relationship of the Reynolds Intellectual Assessment Scales and the Wechsler Adult Intelligence Scale-Third Edition.

PubMed

Smith, Billy L; McChristian, Chrystal L; Smith, Teresa D; Meaux, Julie

2009-08-01

The purpose of this study was to compare scores on the Reynolds Intellectual Assessment Scales (RIAS) with scores on the Wechsler Adult Intelligence Scale-Third Edition (WAIS-III) in a group of college students diagnosed with a Learning Disability, Attention-Deficit Hyperactivity Disorder (ADHD), or a combination of the two. The RIAS Composite Index score was significantly higher than the WAIS-III Full Scale IQ, although scores on both tests were in the average range. Correlations between the two tests were significant on all measures. Male students were significantly higher than female students on both the RIAS Composite Index and on the WAIS-III Full Scale IQ. Although the ADHD group was higher on IQ than the Learning Disabled and combined disorder groups on all IQ measures, no significant differences were found.

Multi-Group Covariance and Mean Structure Modeling of the Relationship between the WAIS-III Common Factors and Sex and Educational Attainment in Spain

ERIC Educational Resources Information Center

Dolan, Conor V.; Colom, Roberto; Abad, Francisco J.; Wicherts, Jelte M.; Hessen, David J.; van de Sluis, Sophie

2006-01-01

We investigated sex effects and the effects of educational attainment (EA) on the covariance structure of the WAIS-III in a subsample of the Spanish standardization data. We fitted both first order common factor models and second order common factor models. The latter include general intelligence ("g") as a second order common factor.…

Orthogonal Higher Order Structure and Confirmatory Factor Analysis of the French Wechsler Adult Intelligence Scale (WAIS-III)

ERIC Educational Resources Information Center

Golay, Philippe; Lecerf, Thierry

2011-01-01

According to the most widely accepted Cattell-Horn-Carroll (CHC) model of intelligence measurement, each subtest score of the Wechsler Intelligence Scale for Adults (3rd ed.; WAIS-III) should reflect both 1st- and 2nd-order factors (i.e., 4 or 5 broad abilities and 1 general factor). To disentangle the contribution of each factor, we applied a…

What Role Does Formal Education Play in the IQ-Age Relationship across the Adult Life-Span?

ERIC Educational Resources Information Center

McLean, James E.; And Others

Age differences in intellect as reflected by performance on the Wechsler Adult Intelligence Scale (Revised) (WAIS-R) were evaluated for persons aged 20 to 74 years. Educational attainment levels were held constant. The WAIS-R sample included 1,480 men and women in the following seven age groups--20-24 years (n=250), 25-34 years (n=250), 35-44…

An exploratory study of the Work Ability Index (WAI) and its components in a group of computer workers.

PubMed

Costa, Ana Filipa; Puga-Leal, Rogério; Nunes, Isabel L

2011-01-01

The objective of this paper is to present a study on the assessment of the work ability of a group of aged computers workers. The study was developed with the goal of creating a decision making framework oriented towards the maintenance of the health and working ability of aged workers. Fifty computer workers participated in this study. They were administrative secretaries and computer technicians working mainly with office computers. The method used to assess the work ability was the Work Ability Index (WAI). 78% of the participants had good or excellent work ability and only 2% a poor one. The average WAI score was 40.5 (SD=5.761; min=27; max=49). This study confirms the decrease in work ability of workers while aging. The group overall work ability was slightly higher than the reference values develop by the Finnish Institute of Occupational Health. The assessment of work ability is fundamental to make age-friendly workplaces. WAI is one tool designed to perform such assessment. The results obtained could assist the early identification of situations where employees are struggling with their work ability, thus helping to prioritize ergonomic interventions devoted to improve the working conditions, and allowing the continued employment of aging workers on their current job.

Development of brief versions of the Wechsler Intelligence Scale for schizophrenia: considerations of the structure and predictability of intelligence.

PubMed

Sumiyoshi, Chika; Uetsuki, Miki; Suga, Motomu; Kasai, Kiyoto; Sumiyoshi, Tomiki

2013-12-30

Short forms (SF) of the Wechsler Intelligence Scale have been developed to enhance its practicality. However, only a few studies have addressed the Wechsler Intelligence Scale Revised (WAIS-R) SFs based on data from patients with schizophrenia. The current study was conducted to develop the WAIS-R SFs for these patients based on the intelligence structure and predictability of the Full IQ (FIQ). Relations to demographic and clinical variables were also examined on selecting plausible subtests. The WAIS-R was administered to 90 Japanese patients with schizophrenia. Exploratory factor analysis (EFA) and multiple regression analysis were conducted to find potential subtests. EFA extracted two dominant factors corresponding to Verbal IQ and Performance IQ measures. Subtests with higher factor loadings on those factors were initially nominated. Regression analysis was carried out to reach the model containing all the nominated subtests. The optimality of the potential subtests included in that model was evaluated from the perspectives of the representativeness of intelligence structure, FIQ predictability, and the relation with demographic and clinical variables. Taken together, the dyad of Vocabulary and Block Design was considered to be the most optimal WAIS-R SF for patients with schizophrenia, reflecting both intelligence structure and FIQ predictability. © 2013 Elsevier Ireland Ltd. All rights reserved.

Performance on the Wechsler Adult Intelligence Scale-III in Japanese patients with schizophrenia.

PubMed

Fujino, Haruo; Sumiyoshi, Chika; Sumiyoshi, Tomiki; Yasuda, Yuka; Yamamori, Hidenaga; Ohi, Kazutaka; Fujimoto, Michiko; Umeda-Yano, Satomi; Higuchi, Arisa; Hibi, Yumiko; Matsuura, Yukako; Hashimoto, Ryota; Takeda, Masatoshi; Imura, Osamu

2014-07-01

Patients with schizophrenia have been reported to perform worse than non-schizophrenic populations on neuropsychological tests, which may be affected by cultural factors. The aim of this study was to examine the performance of a sizable number of patients with schizophrenia on the Japanese version of the Wechsler Adult Intelligence Scale-III (WAIS-III) compared with healthy controls. Performance on the WAIS-III was evaluated in 157 Japanese patients with schizophrenia and in 264 healthy control subjects. All IQ scores and four indices from the WAIS-III were impaired for patients with schizophrenia compared with healthy controls. Processing Speed was markedly disturbed, approximately 2 SD below that of the healthy control group. Among the 13 subtests, Comprehension (z = -1.70, d = 1.55), Digit Symbol Coding (z = -1.84, d = 1.88), and Symbol Search (z = -1.85, d = 1.77) were profoundly impaired relative to the healthy controls. These results indicate that the pattern and degree of impairment, as evaluated by the WAIS-III, in Japanese patients are similar to those previously reported in English-speaking patients and that the deficits of some neuropsychological domains relevant to functional outcomes are universally characteristic of schizophrenia. © 2014 The Authors. Psychiatry and Clinical Neurosciences © 2014 Japanese Society of Psychiatry and Neurology.

Intensity of recreational physical activity throughout life and later life cognitive functioning in women.

PubMed

Tierney, Mary C; Moineddin, Rahim; Morra, Angela; Manson, Judith; Blake, Jennifer

2010-01-01

Long-term physical activity may affect risk of cognitive impairment but few studies have examined later life cognition in relation to intensity of life-long physical activity. We examined the associations between the intensity of long-term recreational physical activity and neuropsychological functioning in 90 healthy postmenopausal women on tests found to be useful in the early identification of dementia. Information was collected about their participation in strenuous and moderate activities between high school and menopause. Summary measures of long-term strenuous and moderate activity were constructed for each participant. All analyses were adjusted for relevant covariates. The six linear regression analyses showed significant positive associations between moderate activity and Wechsler Adult Intelligence Scale Revised (WAIS-R), Digit Span backward, WAIS-R Digit Symbol, and Trail Making Test Part B. Significant negative relationships were found between strenuous activity and Rey Auditory Verbal Learning Test delayed verbal recall, Complex Figure Test delayed visual memory, WAIS-R Digit Span backward, category fluency, and WAIS-R Digit Symbol. The associations found in the present study suggest that while moderate activity may be protective, long-term strenuous activity before menopause may lower cognitive performance later in life. These results support further investigation of the effects of life-long exercise intensity on cognition in later life.

Pediatric chest and abdominopelvic CT: organ dose estimation based on 42 patient models.

PubMed

Tian, Xiaoyu; Li, Xiang; Segars, W Paul; Paulson, Erik K; Frush, Donald P; Samei, Ehsan

2014-02-01

To estimate organ dose from pediatric chest and abdominopelvic computed tomography (CT) examinations and evaluate the dependency of organ dose coefficients on patient size and CT scanner models. The institutional review board approved this HIPAA-compliant study and did not require informed patient consent. A validated Monte Carlo program was used to perform simulations in 42 pediatric patient models (age range, 0-16 years; weight range, 2-80 kg; 24 boys, 18 girls). Multidetector CT scanners were modeled on those from two commercial manufacturers (LightSpeed VCT, GE Healthcare, Waukesha, Wis; SOMATOM Definition Flash, Siemens Healthcare, Forchheim, Germany). Organ doses were estimated for each patient model for routine chest and abdominopelvic examinations and were normalized by volume CT dose index (CTDI(vol)). The relationships between CTDI(vol)-normalized organ dose coefficients and average patient diameters were evaluated across scanner models. For organs within the image coverage, CTDI(vol)-normalized organ dose coefficients largely showed a strong exponential relationship with the average patient diameter (R(2) > 0.9). The average percentage differences between the two scanner models were generally within 10%. For distributed organs and organs on the periphery of or outside the image coverage, the differences were generally larger (average, 3%-32%) mainly because of the effect of overranging. It is feasible to estimate patient-specific organ dose for a given examination with the knowledge of patient size and the CTDI(vol). These CTDI(vol)-normalized organ dose coefficients enable one to readily estimate patient-specific organ dose for pediatric patients in clinical settings. This dose information, and, as appropriate, attendant risk estimations, can provide more substantive information for the individual patient for both clinical and research applications and can yield more expansive information on dose profiles across patient populations within a practice. © RSNA, 2013.

[Standards, options, and recommendations for initial management of patients with malignant ovarian epithelial tumors].

PubMed

Kerbrat, P; Lhommé, C; Fervers, B; Guastalla, J P; Thomas, L; Basuyau, J P; Duvillard, P; Cohen-Solal, C; Dauplat, J; Tournemaine, N

2000-12-09

Suprapubic and transvaginal pelvic ultrasound exploration is indicated for suspected ovarian tumor (standard). Diagnosis and search for extension require surgery and pathology examination. Systematic preoperative computed tomography is not recommended (standard). Surgery for cancer of the ovary is a specialized procedure requiring skill in cancer, gynecology, visceral surgery and laparoscopic surgery. If the patient is referred to a specialized center after a primary procedure considered to be inadequate, a new procedure is recommended for staging. Residual tumor volume after the primary procedure has prognostic value. Systematic second look procedures are not recommended for routine practice (standard). For patients with grade IA G1 tumors, there is no indication for complementary treatment (standard). For patients with grade IA G2-3 or clear cell tumors, IB, IC, IIA, there is no standard. no complementary treatment, complementary chemotherapy using platinum, complementary external abdominopelvic radiotherapy. A complementary treatment is recommended for grades IC and IIA. Complementary treatment for grades IIB (no residual tissue), IIC (with residual tissue), III (no residual tissue), is based on: complementary chemotherapy with platinium, complementary external abdominopelvic radiotherapy (options). Complementary treatment for advanced forms (IIB (with residual tissue), IIC (with residual tissue), III (with residual tissue) and IV) is based on polychemotherapy with platinium (standard). platinium combined with paclitaxel (intravenous), platinium combined with cyclophosphamide and/or doxorubicin (intravenous) or intraperitoneal cisplatin combined with cyclophosphamide (intravenous). The chemotherapy work-up includes physical examination, assay of serum markers (particularly CA125) and abdominopelvic computed tomography (proof level B) (standard). Physical examination is recommended for monitoring patients in complete remission with no sign of suspected recurrence (standard). This document was reviewed in April 1977. The working group again validated the Standards, OPTIONS and Recommendations, without modifications in June 1999.

Risk factors for venous thromboembolic events in pediatric surgical patients: Defining indications for prophylaxis.

PubMed

Cairo, Sarah B; Lautz, Timothy B; Schaefer, Beverly A; Yu, Guan; Naseem, Hibbut-Ur-Rauf; Rothstein, David H

2017-12-27

Venous thromboembolism (VTE) in pediatric surgical patients is a rare event. The risk factors for VTE in pediatric general surgery patients undergoing abdominopelvic procedures are unknown. The American College of Surgeon's National Surgical Quality Improvement Program-Pediatric (NSQIP-P) database (2012-2015) was queried for patients with VTE after abdominopelvic general surgery procedures. Patient and operative variables were assessed to identify risk factors associated with VTE and develop a pediatric risk score. From 2012-2015, 68 of 34,813 (0.20%) patients who underwent abdominopelvic general surgery procedures were diagnosed with VTE. On multivariate analysis, there was no increased risk of VTE based on concomitant malignancy, chemotherapy, inflammatory bowel disease, or laparoscopic surgical approach, while a higher rate of VTE was identified among female patients. The odds of experiencing VTE were increased on stepwise regression for patients older than 15 years and those with preexisting renal failure or a diagnosis of septic shock, patients with American Society of Anesthesia (ASA) classification ≥ 2, and for anesthesia time longer than 2 h. The combination of age > 15 years, ASA classification ≥ 2, anesthesia time > 2 h, renal failure, and septic shock was included in a model for predicting risk of VTE (AUC = 0.907, sensitivity 84.4%, specificity 88.2%). VTE is rare in pediatric patients, but prediction modeling may help identify those patients at heightened risk. Additional studies are needed to validate the factors identified in this study in a risk assessment model as well as to assess the efficacy and cost-effectiveness of prophylaxis methods. Level III, retrospective comparative study. Copyright © 2018. Published by Elsevier Inc.

Centennial-millennial scale variations in Western Antarctic Ice Sheet discharge and their relationship to climate and ocean changes during the late Holocene

NASA Astrophysics Data System (ADS)

Snilstveit Hoem, Frida; Ninnemann, Ulysses S.; Kleiven, Helga (Kikki) F.; Irvali, Nil

2017-04-01

The Western Antarctic Ice Sheet (WAIS) may be highly sensitive to future warming and to ocean driven changes in subsurface melting. Understanding this sensitivity is critical as WAIS dynamics are a major source of uncertainty in sea level rise and regional climate projections. Although there is increasing evidence that WAIS discharge has varied on centennial to multi-millennial timescales since the last glacial period much less is known about its most recent (late Holocene) behavior. This period is particularly important as a baseline for delineating natural and anthropogenic influences and understanding potential coupling between climate, ocean circulation, and WAIS discharge. Here we present high-resolution records of WAIS discharge together with co-registered signals of surface and deep ocean physical property changes in a multicore taken from the southern flank of the North Scotia Sea Ridge (53˚ 31.813 S; 44˚ 42.143 W at 2750m water depth) spanning the past 4000 years. The site is situated just south/east of the polar front beyond the reach of seasonal sea ice and its potentially confounding influence on the ice-rafted debris (IRD) signal but still influenced by icebergs mostly originating from the WAIS. Our record of IRD from core GS08-151-02MC provides a centennially resolved record of iceberg supply from which we infer Antarctic ice-sheet dynamics and variability, while we use the oxygen and carbon isotopic composition of benthic (U. peregrina) and planktonic (N. pachyderma (s)) foraminifera to give (regional) information on past polar deep water and surface water temperatures, circulation and nutrients. Our results show higher amount of IRD between 4200-1800 cal yr B.P. This is in agreement with paleoclimate records reconstructing the onset of the neoglacial, sea ice expansion at about 5000 cal yr B.P. in the Atlantic sector of the Southern Ocean, and glaciers advancing in South America. The strongest IRD peak of the past millennium, which is otherwise a period of generally low IRD, coincides with Little Ice Age at 600 cal yr B.P. The local surface water hydrography appears relatively stable over the past 4000 years with the planktonic δ18O signal indicating centennial-millennial scale changes of typically ≤1˚ C (Δ0.22) and notably smaller in amplitude than the regional warming observed over the past century. The lack of correlation between surface water physical properties and IRD in the downcore records, suggests that IRD is not reflecting iceberg survival but rather changes in the supply (WAIS dynamics) or routing. Consistent with this interpretation, IRD covaries with climate on the Antarctic Peninsula (from JRI ice core) over the past 4 kyr with cooler conditions and lower amounts of IRD over much of the past two millennia than occurred earlier in the neoglaciation. Both records indicate a recovery with warming and increased IRD prior to industrialization. This relationship is consistent with the hypothesis that climate and specifically ocean temperatures were important for modulating WAIS discharge rates over the past few millennia.

The effect of Amifostine (Ethyol) on intestinal anastomosis in rats with radiation enteritis.

PubMed

Ozdemir, C S; Burgazli, K M; Beken-Ozdemir, E; Akdere, H; Mericliler, M; Ozcelik, M F

2013-05-01

Preoperative radiotherapy in colorectal cancers is being used as an adjuvant therapy with increasing frequency. Postoperative complications in early and late periods in various ratios are reported. It has also been shown that radiation has a delaying effect on wound healing and this effect is dose-dependent. This study investigated the effects of the Amifostine on healing of the irradiated colonic anastomosis. 30 female Wistar rats were divided randomly into three groups equally (n=10). Colonic anastomosis were performed to all rats. Group I served as a control. 800 rad abdominopelvic irradiation on the 5th day of preoperation was given to group II and III. Rats in the group III, prior to radiation, were given Amifostine at a dose of 200 mg/kg. On the 5th postoperative day all the rats were sacrificed and the healing of anastomosis was measured with bursting pressure, hydroxyproline levels and histopathological evaluations. Statistical analyses were expressed by analysis of variance (ANOVA) test and p < 0.05 was regarded as significant. In group II, all parameters were found lower compared with control group and Amifostine+Radiation group. As compared with hydroxyproline values and the anastomotic wound healing scores, except group II, no significantly difference were determined between the two other groups. In bursting pressure levels, Group I and III were higher than group II, but not statistically significant (p > 0.05). In group III (Amifostine+Radiation group), the hydroxyproline levels and anastomotic wound healing scores were found significantly higher than group II (p < 0.05), and no significant difference were found between the control group. It is determined that radiation given on the 5th preoperative day has a negative effect on anastomotic wound healing and administered Amifostine prevent this negative effect. In the light of these data, the Amifostine may have a positive effect on preoperative irradiated colonic anastomosis and may play an important role in future on the supporting of the colonic anastomosis.

Using Firn Air for Facility Cooling at the WAIS Divide Site

DTIC Science & Technology

2014-09-17

reduce logistics costs at remote field camps where it is critical to maintain proper temperatures to preserve sensitive deep ice cores. We assessed the...feasibility of using firn air for cooling at the West Antarc- tic Ice Sheet (WAIS) Divide ice core drilling site as a means to adequately and...efficiently refrigerate ice cores during storage and processing. We used estimates of mean annual temperature, temperature variations, and firn

Millimeter-Visible Injection Locking and Testing.

DTIC Science & Technology

1985-12-01

Fetterman , Chewlan Liew, & Wai-Leung Ngai 13a. TYPE OF REPORT 13b. TIME COVERED i 4. DATE OF REPORT (Year, Month, Day) I 5. PAGE COUNT FINAL FROM I Jan...HAROLD FETTERMAN > Accesior For NTIS CA&I DTIC TAB El Unr-no,: :ed [- SJ :st tt:C at i: .. ... ................... B y...Dist, 6btitior; I Av.-),! *j I Of Dist - -206 5 1 Millimeter-Visible Injection Locking and Testing Harold Fetterman , Chewlan Liew, and Wai-Leung

Applying workability in the Australian residential aged care context.

PubMed

Brooke, Elizabeth; Goodall, Joanne; Handrus, Maxwell; Mawren, Daveena

2013-06-01

The study is based on an innovative demonstration project which trialled the implementation of the Finnish 'workability' framework and research measures. It aimed, firstly, to test the applicability of the Workability Index (WAI) to the Australian residential aged care workforce, focusing on personal care assistants (PCAs), and secondly, to assess the effectiveness of actions aimed at improving workability. The facility manager implemented multidimensional 'actions' according to the workability framework. The Workability Survey (WAS) and WAI and intervention instruments were administered (n = 64). Completed responses to 'pre' and 'post' instruments formed matched pairs (n = 15). WAI scores increased significantly, by 3 points on average, after all 'actions' were implemented. The only significant 'action' was increasing the number of PCAs in high care. Workability provides a useful research workforce development instrument measuring interactions between aged care workers and organisational demands and the outcomes of 'actions'. © 2013 The Authors. Australasian Journal on Ageing © 2013 ACOTA.

Math anxiety differentially affects WAIS-IV arithmetic performance in undergraduates.

PubMed

Buelow, Melissa T; Frakey, Laura L

2013-06-01

Previous research has shown that math anxiety can influence the math performance level; however, to date, it is unknown whether math anxiety influences performance on working memory tasks during neuropsychological evaluation. In the present study, 172 undergraduate students completed measures of math achievement (the Math Computation subtest from the Wide Range Achievement Test-IV), math anxiety (the Math Anxiety Rating Scale-Revised), general test anxiety (from the Adult Manifest Anxiety Scale-College version), and the three Working Memory Index tasks from the Wechsler Adult Intelligence Scale-IV Edition (WAIS-IV; Digit Span [DS], Arithmetic, Letter-Number Sequencing [LNS]). Results indicated that math anxiety predicted performance on Arithmetic, but not DS or LNS, above and beyond the effects of gender, general test anxiety, and math performance level. Our findings suggest that math anxiety can negatively influence WAIS-IV working memory subtest scores. Implications for clinical practice include the utilization of LNS in individuals expressing high math anxiety.

Clinical utility of the Wechsler Adult Intelligence Scale-Fourth Edition after traumatic brain injury.

PubMed

Donders, Jacobus; Strong, Carrie-Ann H

2015-02-01

The performance of 100 patients with traumatic brain injury (TBI) on the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) was compared with that of 100 demographically matched neurologically healthy controls. Processing Speed was the only WAIS-IV factor index that was able to discriminate between persons with moderate-severe TBI on the one hand and persons with either less severe TBI or neurologically healthy controls on the other hand. The Processing Speed index also had acceptable sensitivity and specificity when differentiating between patients with TBI who either did or did not have scores in the clinically significant range on the Trail Making Test. It is concluded that WAIS-IV Processing Speed has acceptable clinical utility in the evaluation of patients with moderate-severe TBI but that it should be supplemented with other measures to assure sufficient accuracy in the diagnostic process. © The Author(s) 2014.

Factors related to work ability among Thai workers.

PubMed

Kaewboonchoo, Orawan; Saleekul, Sumlee; Usathaporn, Suthee

2011-01-01

This study aimed to examine the factors related to work ability among small and medium enterprise (SME) workers in Thailand. The subjects consisted of 845 males and 1,163 females. They were interviewed regarding personal information, working conditions, health status, job stress and work ability. Their blood pressure, body weight and height were also measured. More than half the subjects reported high job stress. Women had higher job stress than men. The work ability index (WAI) results for managers, supervisors and operators were 42.3, 41.4 and 39.8, respectively. Job control of managers and supervisors was higher than operators. The WAI of females decreased with increasing age for those over age 45 years. Factors related to WAI were mental health, social support at work, depression and age. The results suggest job stress reduction programs should be considered to improve work ability among SME workers.

Structural and incremental validity of the Wechsler Adult Intelligence Scale-Fourth Edition with a clinical sample.

PubMed

Nelson, Jason M; Canivez, Gary L; Watkins, Marley W

2013-06-01

Structural and incremental validity of the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV; Wechsler, 2008a) was examined with a sample of 300 individuals referred for evaluation at a university-based clinic. Confirmatory factor analysis indicated that the WAIS-IV structure was best represented by 4 first-order factors as well as a general intelligence factor in a direct hierarchical model. The general intelligence factor accounted for the most common and total variance among the subtests. Incremental validity analyses indicated that the Full Scale IQ (FSIQ) generally accounted for medium to large portions of academic achievement variance. For all measures of academic achievement, the first-order factors combined accounted for significant achievement variance beyond that accounted for by the FSIQ, but individual factor index scores contributed trivial amounts of achievement variance. Implications for interpreting WAIS-IV results are discussed. (PsycINFO Database Record (c) 2013 APA, all rights reserved).

[Application of WAIS-RC short forms and adult intelligence disability scale in mental impairment assessment].

PubMed

Pang, Yan-Xia; Zhang, Jian; Yang, Cheng-Long; Cang, Yong; Wang, Xue-Ling

2011-06-01

Study on the application of WAIS-RC short forms and adult intelligence disability scale in mental impairment assessment. Mental impairment assessment cases between July 2009 and March 2011 in judicial appraisal institute of Taizhou University were collected. Assessment results obtained with the WAIS-RC short forms and adult intelligence disability scale were compared with the experts assessing conclusions and analyzed using SPSS 11.5 software. Assessment results with the two scales did not fully comply with the expert's conclusions, with reliability coefficient were 0.785 and 0.940 respectively, correlation coefficient were 0.850 and 0.922 respectively. The intelligence assessment was influenced by many factors. When the appraised individuals had nerve dysfunction and mild intelligence disability or mental disorders, the two scales should be used together. When the appraised individuals had moderate intelligence disability or mental disorders, adult intelligence disability scale had advantage.

Atmospheric CO2 Over the Last 1000 Years: WAIS Divide Ice Core Record

NASA Astrophysics Data System (ADS)

Ahn, J.; Brook, E. J.

2009-04-01

How atmospheric CO2 varied over the last thousands years is of great interest because we may see not only natural, but also anthropogenic variations (Ruddiman, Climatic Change, 2003). The Law Dome ice cores reveal decadal to centennial variations in CO2 over the last 2000 years (MacFarling Meure et al., Geophys. Res. Lett., 2006). However, these variations have not yet been well confirmed in other ice core records. Here we use a newly drilled WAIS Divide ice core, which is ideal for this purpose because WAIS Divide has relatively high snow accumulation rate and small gas age distribution that allow us to observe decadal CO2 variations with minimal damping. We have started an extensive study of CO2 in WAIS Divide core. So far we have obtained data for 960-1940 A.D. from the WDC05-A core drilled in 2005-2006. 344 ice samples from 103 depths were analyzed and the standard error of the mean is ~0.8 ppm on average. Ancient air in 8~12 g of bubbly ice is liberated by crushing with steel pins at -35 °C and trapped in stainless steel tubes at -262 °C. CO2 mixing ratio in the extracted air is precisely determined using a gas chromatographic method. Details of the high-precision methods are described in Ahn et al. (J. of Glaciology, in press). Our new results show preindustrial atmospheric CO2 variability of ~ 10 ppm. The most striking feature of the record is a rapid atmospheric CO2 decrease of 7~8 ppm within ~20 years at ~ 1600 A.D. Considering the larger smoothing of gas records in the WAIS Divide relative to Law Dome, our results confirm the atmospheric CO2 decrease of ~10 ppm in Law Dome records observed at this time. However, this event is not significant in the Dronning Maud Land ice core (Siegenthaler et al., Tellus, 2005), probably due to more extensive smoothing of gas records in the core. Similar rapid changes of CO2 at other times in the WAIS Divide record need to be confirmed with higher resolution studies. We also found that our WAIS Divide CO2 data are slightly higher than those of Law Dome by 3~5 ppm over most of the record. It is not clear whether the offset is due to real variability in ice cores or an analytical offset. We are participating in international laboratory intercalibration to determine the origin of the offset. Several WDC05-A and Law Dome ice samples are shared and will be analyzed for data comparison with CSIRO (Australian Common Wealth Scientific and Research Organization).

Effect of abdominopelvic abscess drain size on drainage time and probability of occlusion

PubMed Central

Rotman, Jessica A.; Getrajdman, George I.; Maybody, Majid; Erinjeri, Joseph P.; Yarmohammadi, Hooman; Sofocleous, Constantinos T.; Solomon, Stephen B.; Boas, F. Edward

2016-01-01

Background The purpose of this study is to determine whether larger abdominopelvic abscess drains reduce the time required for abscess resolution, or the probability of tube occlusion. Methods 144 consecutive patients who underwent abscess drainage at a single institution were reviewed retrospectively. Results: Larger initial drain size did not reduce drainage time, drain occlusion, or drain exchanges (p>0.05). Subgroup analysis did not find any type of collection that benefitted from larger drains. A multivariate model predicting drainage time showed that large collections (>200 ml) required 16 days longer drainage time than small collections (<50 ml). Collections with a fistula to bowel required 17 days longer drainage time than collections without a fistula. Initial drain size and the viscosity of the fluid in the collection had no significant effect on drainage time in the multivariate model. Conclusions 8 F drains are adequate for initial drainage of most serous and serosanguineous collections. 10 F drains are adequate for initial drainage of most purulent or bloody collections. PMID:27634422

[Work stress, common mental disorders and Work Ability Index among call center workers of an Italian company].

PubMed

Conway, Paul Maurice; Campanini, Paolo; Punzi, Silvia; Fichera, Giuseppe Paolo; Camerino, Donatella; Francioli, Laura; Neri, Luca; Costa, Giovanni

2013-01-01

To test three hypotheses in an Italian sample of call center workers: higher levels of perceived work stress are associated with more frequent common mental disorders (GHQ-12) and a lower Work Ability Index; combining the Job Strain (JS) and Effort/Reward Imbalance (ERI) models increases explained variance in health over and above either model when applied separately; compared with outbound operators, inbound call handlers are expected to report a lower health status,which is due to a more intense exposure to task-related work stress factors in the latter. A multi-center cross-sectional study, conducted by means of interviews and self-administered questionnaires. Call handlers working in the Italian branch of a telecommunication multinational company. In all, 1,106 permanent workers were examined (35.9%of the total target population, 98.9% response rate). The majority were women (76.5%);mean age was 33.3 (SD: 3.9) and company seniority 8.0 (SD: 2.1). Nearly 60% worked as inbound call handlers, about one third as outbound operators. Work stress was measured with the well-known JS and ERI models. Three exposure levels (based on tertiles) were identified for each scale. Common mental disorders were measured with the GHQ-12 questionnaire. Subjects with a GHQ-12 score 4 were classified as "cases". The Work Ability Index (WAI) was used to evaluate work ability. Being in the "poor" or "moderate" categories of the WAI indicated a low work ability status. Cronbach's alphas were 0.70 for all scales. Multivariate Poisson regressions showed that both models were linked to more frequent common mental disorders and a lower WAI. Moreover, combined models demonstrated an advantage in terms of explained variance in health. Finally, performing inbound call handling was associated with a lower WAI in comparison with engaging in outbound activities. Mediation analyses showed that such association is explained by the higher levels of psychological job demands and Job Strain experienced by inbound operators. Our results highlight the relevance of work stress as a risk factor for lower psychological health, and especially for a poorer WAI among call center workers. The combined use of the two models increases completeness of work stress assessment in this sector.The higher levels of work stress and the lower WAI observed among inbound operators are due to objectively less favourable task-related characteristics.

[A multilevel model analysis of correlation between population characteristics and work ability of employees].

PubMed

Zhang, Lei; Huang, Chunping; Lan, Yajia; Wang, Mianzhen

2015-12-01

To analyze the correlation between population characteristics and work ability of employees with a multilevel model, to investigate the important influencing factors for work ability, and to provide a basis for improvement in work ability. Work ability index (WAI)was applied to measure the work ability of 1686 subjects from different companies (n=6). MLwi N2.0 software was applied for two-level variance component model fitting. The WAI of employees showed differences between various companies (χ2=3.378 6, P=0.0660); working years was negatively correlated with WAI (χ2=38.229 2, P=0.0001), and the WAI of the employees with 20 or more working years was 1.63 lower than that of the employees with less than 20 working years; the work ability of manual workers was lower than that of mental-manual workers (χ2=8.2726, P=0.0040), and the work ability showed no significant difference between mental workers and mental-manual workers (χ2=2.086 0, P=0.148 7). From the perspective of probability, the multilevel model analysis reveals the differences in work ability of employees between different companies, and suggests that company, work type, and working years are the important influencing factors for work ability of employees. These factors should be improved and adjusted to protect or enhance the work ability of employees.

Measuring Work Ability with Its Antecedents: Evaluation of the Work Ability Survey.

PubMed

Voltmer, Jan-Bennet; Deller, Jürgen

2017-07-24

Purpose The revised version of the Work Ability Survey (WAS-R) assesses work ability on several sub-scales at the intersection of personal and organizational capacity, thus adding to the measurement of work ability by integrating the holistic model. It, therefore, improves on two features of the current standard measurement tool of work ability, the Work Ability Index (WAI): (1) a ceiling effect and (2) limited detail due to a focus on physical health and personal capacity. Method In two samples (n 1  = 1093, n 2  = 359), psychometric properties and the structure of the WAS-R were analyzed. To evaluate construct validity, inter-correlations of the WAS-R and WAI, sickness absence, expected and desired retirement age, and post-retirement work intention were calculated. Results The WAS-R was found to be distributed closer to normality than the WAI. The structural analyses yielded acceptable results for the hypothesized model. The WAS-R was adequately correlated with the WAI, negatively with sickness absence, and positively with desired retirement age. Conclusions The WAS-R extends the measurement of work ability, reflecting organizations' work demands. Its broad sub-scales lead to high acceptance of the results within the participating companies. In particular, the organizational capacity scales can be used to guide interventions aiming at organizational characteristics to improve work ability.

[Job satisfaction and work ability index in nurses].

PubMed

Viola, Fiorella; Larese Filon, Francesca

2015-01-22

Job satisfaction and work ability are important in the nursing profession to ensure good working conditions and to reduce work-related diseases and illness. Psychosocial factors such as social support and decision latitude (autonomy) could have a role in cardiovascular diseases, low back pain, injuries and sick leave. To evaluate work ability, job satisfaction, psychosocial factors and diseases in 10 departments of the Monfalcone Hospital. The Work Ability Index (WAI) questionnaire and Karasek Job Content Questionnaire with other questions related to working conditions and diseases were administered to 160 nurses working in 10 departments. The response rate was 90%. SPSS Statistic packaging was used for statistical analysis. The study population had a mean age of 41.1 ± 7 years and the majority were female (81.25%). WAI gave a rating of over 37 points (good and excellent) for 86.4%, with an average of 39.9 ± 5.9 in women and 40.6 ± 6.4 in men. The WAI differences between the departments were significant with Medicine and Surgery showing lower values (p=0.012). WAI was significantly lower in subjects with sick leave higher than 10 days per year (p=0.000) and in subjects with cardiovascular diseases (p=0.031). Our study showed very good working conditions for nurses. A follow-up of the analyzed population over time will add further information on this aspect.

Variability in Wechsler Adult Intelligence Scale-IV subtest performance across age.

PubMed

Wisdom, Nick M; Mignogna, Joseph; Collins, Robert L

2012-06-01

Normal Wechsler Adult Intelligence Scale (WAIS)-IV performance relative to average normative scores alone can be an oversimplification as this fails to recognize disparate subtest heterogeneity that occurs with increasing age. The purpose of the present study is to characterize the patterns of raw score change and associated variability on WAIS-IV subtests across age groupings. Raw WAIS-IV subtest means and standard deviations for each age group were tabulated from the WAIS-IV normative manual along with the coefficient of variation (CV), a measure of score dispersion calculated by dividing the standard deviation by the mean and multiplying by 100. The CV further informs the magnitude of variability represented by each standard deviation. Raw mean scores predictably decreased across age groups. Increased variability was noted in Perceptual Reasoning and Processing Speed Index subtests, as Block Design, Matrix Reasoning, Picture Completion, Symbol Search, and Coding had CV percentage increases ranging from 56% to 98%. In contrast, Working Memory and Verbal Comprehension subtests were more homogeneous with Digit Span, Comprehension, Information, and Similarities percentage of the mean increases ranging from 32% to 43%. Little change in the CV was noted on Cancellation, Arithmetic, Letter/Number Sequencing, Figure Weights, Visual Puzzles, and Vocabulary subtests (<14%). A thorough understanding of age-related subtest variability will help to identify test limitations as well as further our understanding of cognitive domains which remain relatively steady versus those which steadily decline.

The aeromagnetic method as a tool to identify Cenozoic magmatism in the West Antarctic Rift System beneath the West Antarctic Ice Sheet: a review; Thiel subglacial volcano as possible source of the ash layer in the WAISCOR

USGS Publications Warehouse

Behrendt, John C.

2013-01-01

The West Antarctic Ice Sheet (WAIS) flows through the volcanically active West Antarctic Rift System (WARS). The aeromagnetic method has been the most useful geophysical tool for identification of subglacial volcanic rocks, since 1959–64 surveys, particularly combined with 1978 radar ice-sounding. The unique 1991–97 Central West Antarctica (CWA) aerogeophysical survey covering 354,000 km2 over the WAIS, (5-km line-spaced, orthogonal lines of aeromagnetic, radar ice-sounding, and aerogravity measurements), still provides invaluable information on subglacial volcanic rocks, particularly combined with the older aeromagnetic profiles. These data indicate numerous 100–>1000 nT, 5–50-km width, shallow-source, magnetic anomalies over an area greater than 1.2 × 106 km2, mostly from subglacial volcanic sources. I interpreted the CWA anomalies as defining about 1000 “volcanic centers” requiring high remanent normal magnetizations in the present field direction. About 400 anomaly sources correlate with bed topography. At least 80% of these sources have less than 200 m relief at the WAIS bed. They appear modified by moving ice, requiring a younger age than the WAIS (about 25 Ma). Exposed volcanoes in the WARS are The present rapid changes resulting from global warming, could be accelerated by subglacial volcanism.

Can we improve the clinical assessment of working memory? An evaluation of the Wechsler Adult Intelligence Scale-Third Edition using a working memory criterion construct.

PubMed

Hill, B D; Elliott, Emily M; Shelton, Jill T; Pella, Russell D; O'Jile, Judith R; Gouvier, W Drew

2010-03-01

Working memory is the cognitive ability to hold a discrete amount of information in mind in an accessible state for utilization in mental tasks. This cognitive ability is impaired in many clinical populations typically assessed by clinical neuropsychologists. Recently, there have been a number of theoretical shifts in the way that working memory is conceptualized and assessed in the experimental literature. This study sought to determine to what extent the Wechsler Adult Intelligence Scale-Third Edition (WAIS-III) Working Memory Index (WMI) measures the construct studied in the cognitive working memory literature, whether an improved WMI could be derived from the subtests that comprise the WAIS-III, and what percentage of variance in individual WAIS-III subtests is explained by working memory. It was hypothesized that subtests beyond those currently used to form the WAIS-III WMI would be able to account for a greater percentage of variance in a working memory criterion construct than the current WMI. Multiple regression analyses (n = 180) revealed that the best predictor model of subtests for assessing working memory was composed of the Digit Span, Letter-Number Sequencing, Matrix Reasoning, and Vocabulary. The Arithmetic subtest was not a significant contributor to the model. These results are discussed in the context of how they relate to Unsworth and Engle's (2006, 2007) new conceptualization of working memory mechanisms.

Rapidly-administered short forms of the Wechsler Adult Intelligence Scale-3rd edition.

PubMed

Donnell, Alison J; Pliskin, Neil; Holdnack, James; Axelrod, Bradley; Randolph, Christopher

2007-11-01

Although the Wechsler Full Scale IQ (FSIQ) is a common component of most neuropsychological evaluations, there are many clinical situations where the complete administration of this battery is precluded by various constraints, including limitations of time and patient compliance. These constraints are particularly true for dementia evaluations involving elderly patients. The present study reports data on two short forms particularly suited to dementia evaluations, each requiring less than 20min of administration time. One of the short forms was previously validated in dementia for the WAIS-R [Randolph, C., Mohr, E., & Chase, T. N. (1993). Assessment of intellectual function in dementing disorders: Validity of WAIS-R short forms for patients with Alzheimer's, Huntington's, and Parkinson's disease. Journal of Clinical and Experimental Neuropsychology, 15, 743-753]; the second was developed specifically for patients with motor disabilities. These short forms were validated using the WAIS-III normative standardization sample (N=2450), neurologic sample (N=63), and matched controls (N=49), and a separate mixed clinical sample (N=70). The results suggest that each short form provides an accurate and reliable estimate of WAIS-III FSIQ, validating their use in appropriate clinical contexts. The present data support the use of these short forms for dementia evaluations, and suggests that they may be applicable for the evaluation of other neurological and neuropsychiatric disorders that involve acquired neurocognitive impairment.

Relationship between Work Ability Index and Cognitive Failure among Nurses.

PubMed

Abbasi, Milad; Zakerian, Abolfazl; Kolahdouzi, Malihe; Mehri, Ahmad; Akbarzadeh, Arash; Ebrahimi, Mohammad Hossein

2016-03-01

Frequent nursing errors are considered as factors that affect the quality of healthcare of patients. Capable nurses who are compatible with work conditions are more focused on their tasks, and this reduces their errors and cognitive failures. Therefore, this study was conducted with the aim of investigating the relationship between work ability index (WAI) and cognitive failures (CFs) as well as some factors that affect them in nurses working in the ICU, CCU, and emergency wards. This descriptive-analytical and cross-sectional study was conducted with 750 nurses at educational hospitals affiliated with the Tehran University of Medical Sciences in 2015. A questionnaire of work ability index and cognitive failures was used to collect data. The data were analyzed using SPSS 20 and the Pearson and Spearman correlation coefficients, chi-squared, ANOVA, and the Kruskal-Wallis tests. Using the Pearson correlation test, the results of this study showed that there is a significant, inverse relationship between WAI, personal prognosis of work ability, and mental resources with CFs along with all its subscales in nurses (p < 0.05). In addition, there was an inverse and significant relationship between the total score of CFs and the estimated work impairment due to diseases (p < 0.05). There was a significant positive correlation of CFs with age and experience, while WAI was inversely related to age, work experience, and body mass index (BMI) (p < 0.05). WAI and CFs were related significantly to working units (p < 0.05). Considering the results obtained in this study, WAI and the cognitive status of nurses were lower than the specified limit. It is suggested that the work ability of nurses be improved and that their CFs be reduced through various measures, including pre-employment examinations, proper management of work-shift conditions, and using engineering and administrative strategies to ensure the safety of hospitalized patients.

Long-term Glacial History of the West Antarctic Ice Sheet from Cosmogenic Nuclides in a Subglacial Bedrock Core

NASA Astrophysics Data System (ADS)

Spector, P. E.; Stone, J.; Hillebrand, T.; Gombiner, J. H.

2017-12-01

To investigate the response of the West Antarctic Ice Sheet (WAIS) to climatic conditions warmer than present, we are analyzing cosmogenic nuclides in a bedrock core from beneath 150 m of ice at a site near the Pirrit Hills. Our aim is to determine whether the WAIS has thinned in the past, exposing bedrock at this site, and if so, when. This will help to determine the vulnerability of the ice sheet to future warming, and identify climatic thresholds capable of inducing WAIS collapse. We selected a site where the ice-sheet surface lies at 1300 m, approximately halfway from the ice-sheet divide to the grounding line. We expect ice thickness at the site to reflect WAIS dynamics, rather than local meteorology or topography. Ice flow speeds are moderate and ice above the core site is thin enough to remain cold-based, limiting the possibility of subglacial erosion which would compromise the cosmogenic nuclide record. We targeted a subglacial ridge adjacent to an exposed granite nunatak. This lithology provides minerals suitable for analysis of multiple cosmogenic nuclides with different half-lives. Although we aimed to collect two cores from different depths to compare exposure histories, hydrofracture of the basal ice prevented us from reaching the bed at the first drill site. The second hole produced 5.5 m of discontinuous ice core above 8 m of bedrock core. Initial analyses of quartz from the bedrock show low levels of Be-10. Further analyses of Be-10, Al-26, Cl-36 and Ne-21 from the full length of the core will be required to determine whether this is because the surface has never been exposed, or because the cosmogenic nuclide profile has been truncated by glacial erosion. We will present comprehensive cosmogenic nuclide data, and discuss implications for WAIS deglaciation history, at the meeting. Supported by US National Science Foundation awards ANT-1142162 and PLR-1341728.

The diatom record from beneath the West Antarctic Ice Sheet and the global proxy perspective

NASA Technical Reports Server (NTRS)

Scherer, Reed P.

1993-01-01

Recent glaciological evaluation and modeling of the marine-based West Antarctic Ice Sheet (WAIS) support the possibility that the WAIS disintegrated during one or more Pleistocene interglacial period(s). The magnitude of sea level and oxygen isotope variation during certain late-Pleistocene interglacial periods is also consistent with the possibility of major retreat of the WAIS. Although oxygen isotopes from deep-sea sediments provide the best available proxy record for global ice volume (despite the ambiguities in the record), the source of ice volume changes must be hypothesized. Based on the intensity of interglacial isotopic shifts recorded in Southern Ocean marine sedimentary records, stage 11 (400,000 years ago) is the strongest candidate for WAIS collapse, but the records for stages 9, 7, and 5.5 are all consistent with the possibility of multiple late-Pleistocene collapses. Seismic reflection studies through the WAIS have revealed thick successions of strata with seismic characteristics comparable to upper Tertiary marine sediments. Small samples of glacial diamictons from beneath the ice sheet have been collected via hot-water drilled access holes. These sediments include mixed diatom assemblages of varying ages. Late-Miocene diatoms dominate many samples, probably reflecting marine deposition in West Antarctic basins prior to development of a dominantly glacial phase in West Antarctica. In addition to late-Miocene diatoms, samples from Upstream B (1988/89) contain rare post-Miocene diatoms, many of which imply deposition in the West Antarctic interior during one or more Pleistocene deglaciation periods. Age-diagnostic fossils in glacial sediments beneath ice sheets provide relatively coarse chronostratigraphic control, but they do contain direct evidence of regional deglaciation. Thus, sub-glacial till samples provide the evidence regarding the source of ice sheet variability seen in well-dated proxy records. Combined, these independent data sets can provide a more comprehensive and less speculative interpretation of the history of past glacial minima in currently glaciated polar regions.

Negative magnetic anomaly over Mt. Resnik, a subaerially erupted volcanic peak beneath the West Antarctic Ice Sheet

USGS Publications Warehouse

Behrendt, John C.; Finn, C.; Morse, D.L.; Blankenship, D.D.

2006-01-01

Mt. Resnik is one of the previously reported 18 subaerially erupted volcanoes (in the West Antarctic rift system), which have high elevation and high bed relief beneath the WAIS in the Central West Antarctica (CWA) aerogeophysical survey. Mt. Resnik lies 300 m below the surface of the West Antarctic Ice Sheet (WAIS); it has 1.6 km topographic relief, and a conical form defined by radar ice-sounding of bed topography. It has an associated complex negative magnetic anomaly revealed by the CWA survey. We calculated and interpreted magnetic models fit to the Mt. Resnik anomaly as a volcanic source comprising both reversely and normally magnetized (in the present field direction) volcanic flows, 0.5-2.5-km thick, erupted subaerially during a time of magnetic field reversal. The Mt. Resnik 305-nT anomaly is part of an approximately 50- by 40-km positive anomaly complex extending about 30 km to the west of the Mt. Resnik peak, associated with an underlying source complex of about the same area, whose top is at the bed of the WAIS. The bed relief of this shallow source complex has a maximum of only about 400 m, whereas the modeled source is >3 km thick. From the spatial relationship we interpret that this source and Mt Resnik are approximately contemporaneous. Any subglacially (older?) erupted edifices comprising hyaloclastite or other volcanic debris, which formerly overlaid the source to the west, were removed by the moving WAIS into which they were injected as is the general case for the ???1000 volcanic centers at the base of the WAIS. The presence of the magnetic field reversal modeled for Mt. Resnik may represent the Bruhnes-Matayama reversal at 780 ka (or an earlier reversal). There are ???100 short-wavelength, steep-gradient, negative magnetic anomalies observed over the West Antarctic Ice Sheet (WAIS), or about 10% of the approximately 1000 short-wavelength, shallow-source, high-amplitude (50- >1000 nT) "volcanic" magnetic anomalies in the CWA survey. These negative anomalies indicate volcanic activity during a period of magnetic reversal and therefore must also be at least 780 ka. The spatial extent and volume of volcanism can now be reassessed for the 1.2 ?? 106 km2 region of the WAIS characterized by magnetic anomalies defining interpreted volcanic centers associated with the West Antarctic rift system. The CWA covers an area of 3.54 ?? 105 km2; forty-four percent of that area exhibits short-wavelength, high-amplitude anomalies indicative of volcanic centers and subvolcanic intrusions. This equates to an area of 0.51 ?? 105 km2 and a volume of 106 km3 beneath the ice-covered West Antarctic rift system, of sufficient extent to be classified as a large igneous province interpreted to be of Oligocene to recent age.

Cognitive profiles of adults with high-functioning autism spectrum disorder and those with attention-deficit/hyperactivity disorder based on the WAIS-III.

PubMed

Kanai, Chieko; Hashimoto, Ryuichiro; Itahashi, Takashi; Tani, Masayuki; Yamada, Takashi; Ota, Haruhisa; Iwanami, Akira; Kato, Nobumasa

2017-02-01

The cognitive profile differences between adult patients with autism spectrum disorder (ASD) and those with attention-deficit/hyperactivity disorder (ADHD) are not well characterized. We examined the cognitive profiles of adults having either ASD (n=120) or ADHD (n=76) with no intellectual disabilities (IQ≥70) using the Wechsler Intelligence Scale III (WAIS-III). Verbal Intelligence (VIQ) - Performance Intelligence (PIQ) difference discrepancies were detected between the two groups. Information subtest scores of the Verbal Comprehension index and Arithmetic and Digit Span subtests of the Freedom from Distractibility index were significantly higher in ASD than in ADHD, while the Picture Completion subtest was significantly lower in ASD. To our knowledge, this is the first study to evaluate the difference in the cognitive profiles of adults with ASD and those with ADHD based on the WAIS III with a large number of participants. Copyright © 2016 Elsevier Ltd. All rights reserved.

The relationship between work ability and oxidative stress in Japanese workers.

PubMed

Ohta, Masanori; Kumashiro, Masaharu; Eguchi, Yasumasa; Morita, Yusaku; Konno, Yoshimasa; Yamato, Hiroshi

2014-01-01

Work ability is based on the balance between personal resources and work demand. This study focused on the personal resources component of work ability. The aims of this study were to elucidate the association between work ability and cardiovascular (CV) risk factors, particularly oxidative stress, and to estimate the effect of a community-implemented lifestyle modification programme on work ability and CV risk factors. Urinary 8-iso-prostaglandin F2α (PGF2α), a biomarker of oxidative stress, was negatively correlated with psychological resources, as measured by the Work Ability Index (WAI). Overall WAI score was unchanged following the programme, while CV risk factors and antioxidative activity improved. A reduction in PGF2α levels was correlated with an improvement in subjective work ability relative to job demands, as assessed by a WAI item. Taken together, the results suggest that lifestyle modification programmes enhance the personal resources component of work ability and are associated with a reduction in oxidative stress.

The Afro-Cardiac Study: Cardiovascular Disease Risk and Acculturation in West African Immigrants in the United States: Rationale and Study Design.

PubMed

Commodore-Mensah, Yvonne; Sampah, Maame; Berko, Charles; Cudjoe, Joycelyn; Abu-Bonsrah, Nancy; Obisesan, Olawunmi; Agyemang, Charles; Adeyemo, Adebowale; Himmelfarb, Cheryl Dennison

2016-12-01

Cardiovascular disease (CVD) remains the leading cause of death in the United States (US). African-descent populations bear a disproportionate burden of CVD risk factors. With the increase in the number of West African immigrants (WAIs) to the US over the past decades, it is imperative to specifically study this new and substantial subset of the African-descent population and how acculturation impacts their CVD risk. The Afro-Cardiac study, a community-based cross-sectional study of adult WAIs in the Baltimore-Washington metropolis. Guided by the PRECEDE-PROCEED model, we used a modification of the World Health Organization Steps survey to collect data on demographics, socioeconomic status, migration-related factors and behaviors. We obtained physical, biochemical, acculturation measurements as well as a socio-demographic and health history. Our study provides critical data on the CVD risk of WAIs. The framework used is valuable for future epidemiological studies addressing CVD risk and acculturation among immigrants.

WAIS-III index score profiles in the Canadian standardization sample.

PubMed

Lange, Rael T

2007-01-01

Representative index score profiles were examined in the Canadian standardization sample of the Wechsler Adult Intelligence Scale-Third Edition (WAIS-III). The identification of profile patterns was based on the methodology proposed by Lange, Iverson, Senior, and Chelune (2002) that aims to maximize the influence of profile shape and minimize the influence of profile magnitude on the cluster solution. A two-step cluster analysis procedure was used (i.e., hierarchical and k-means analyses). Cluster analysis of the four index scores (i.e., Verbal Comprehension [VCI], Perceptual Organization [POI], Working Memory [WMI], Processing Speed [PSI]) identified six profiles in this sample. Profiles were differentiated by pattern of performance and were primarily characterized as (a) high VCI/POI, low WMI/PSI, (b) low VCI/POI, high WMI/PSI, (c) high PSI, (d) low PSI, (e) high VCI/WMI, low POI/PSI, and (f) low VCI, high POI. These profiles are potentially useful for determining whether a patient's WAIS-III performance is unusual in a normal population.

Application of new WAIS-III/WMS-III discrepancy scores for evaluating memory functioning: relationship between intellectual and memory ability.

PubMed

Lange, Rael T; Chelune, Gordon J

2006-05-01

Analysis of the discrepancy between memory and intellectual ability has received some support as a means for evaluating memory impairment. Recently, comprehensive base rate tables for General Ability Index (GAI) minus memory discrepancy scores (i.e., GAI-memory) were developed using the WAIS-III/WMS-III standardization sample (Lange, Chelune, & Tulsky, in press). The purpose of this study was to evaluate the clinical utility of GAI-memory discrepancy scores to identify memory impairment in 34 patients with Alzheimer's type dementia (DAT) versus a sample of 34 demographically matched healthy participants. On average, patients with DAT obtained significantly lower scores on all WAIS-III and WMS-III indexes and had larger GAI-memory discrepancy scores. Clinical outcome analyses revealed that GAI-memory scores were useful at identifying memory impairment in patients with DAT versus matched healthy participants. However, GAI-memory discrepancy scores failed to provide unique interpretive information beyond that which is gained from the memory indexes alone. Implications and future research directions are discussed.

ARM West Antarctic Radiation Experiment (AWARE) Field Campaign Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lubin, Daniel; Bromwich, David H; Vogelmann, Andrew M

The U.S. Department of Energy (DOE) Atmospheric Radiation Measurement (ARM) West Antarctic Radiation Experiment (AWARE) is the most technologically advanced atmospheric and climate science campaign yet fielded in Antarctica. AWARE was motivated be recent concern about the impact of cryospheric mass loss on global sea level rise. Specifically, the West Antarctic Ice Sheet (WAIS) is now the second largest contributor to rising sea level, after the Greenland Ice Sheet. As steadily warming ocean water erodes the grounding lines of WAIS components where they meet the Amundsen and Bellingshausen Seas, the retreating grounding lines moving inland and downslope on the underlyingmore » terrain imply mechanical instability of the entire WAIS. There is evidence that this point of instability may have already been reached, perhaps signifying more rapid loss of WAIS ice mass. At the same time, the mechanical support provided by adjacent ice shelves, and also the fundamental stability of exposed ice cliffs at the ice sheet grounding lines, will be adversely impacted by a warming atmosphere that causes more frequent episodes of surface melting. The surface meltwater damages the ice shelves and ice cliffs through hydrofracturing. With the increasing concern regarding these rapid cryospheric changes, AWARE was motivated by the need to (a) diagnose the surface energy balance in West Antarctica as related to both summer season climatology and potential surface melting, and (b) improve global climate model (GCM) performance over Antarctica, such that future cryospheric projections can be more reliable.« less

African Ancestry Gradient Is Associated with Lower Systemic F2-Isoprostane Levels

PubMed Central

Annor, Francis; Okosun, Ike; Gower, Barbara A.

2017-01-01

Context. Low levels of systemic F2-isoprostanes (F2-IsoP) increase the risk of diabetes and weight gain and were found in African Americans. Low F2-IsoPs could reflect an unfavorable metabolic characteristic, namely, slow mitochondrial metabolism in individuals with African ancestry. Objective. To examine differences in plasma F2-IsoPs in three groups with a priori different proportion of African ancestry: non-Hispanic Whites (NHWs), US-born African Americans (AAs), and West African immigrants (WAI). Design. Cross-sectional study. Setting. Georgia residents recruited from church communities. Participants. 218 males and females 25–74 years of age, who are self-identified as NHW (n = 83), AA (n = 56), or WAI (n = 79). Main Outcome Measure(s). Plasma F2-IsoPs quantified by gas chromatography-mass spectrometry. Results. After adjustment for age, gender, obesity, and other comorbidities, WAI had lower levels of plasma F2-IsoP than AA (beta-coefficient = −9.8, p < 0.001) and AA had lower levels than NHW (beta-coefficient = −30.3, p < 0.001). Similarly, among healthy nonobese participants, F2-IsoP levels were lowest among WAI, followed by AA, and the highest levels were among NHW. Conclusion. Plasma F2-IsoPs are inversely associated with African ancestry gradient. Additional studies are required to test whether optimization of systemic F2-IsoP levels can serve as means to improve race-specific lifestyle and pharmacological intervention targeted to obesity prevention and treatment. PMID:28250893

Incidental Learning: A Brief, Valid Measure of Memory Based on the WAIS-IV Vocabulary and Similarities Subtests.

PubMed

Spencer, Robert J; Reckow, Jaclyn; Drag, Lauren L; Bieliauskas, Linas A

2016-12-01

We assessed the validity of a brief incidental learning measure based on the Similarities and Vocabulary subtests of the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV). Most neuropsychological assessments for memory require intentional learning, but incidental learning occurs without explicit instruction. Incidental memory tests such as the WAIS-III Symbol Digit Coding subtest have existed for many years, but few memory studies have used a semantically processed incidental learning model. We conducted a retrospective analysis of 37 veterans with traumatic brain injury, referred for outpatient neuropsychological testing at a Veterans Affairs hospital. As part of their evaluation, the participants completed the incidental learning tasks. We compared their incidental learning performance to their performance on traditional memory measures. Incidental learning scores correlated strongly with scores on the California Verbal Learning Test-Second Edition (CVLT-II) and Brief Visuospatial Memory Test-Revised (BVMT-R). After we conducted a partial correlation that controlled for the effects of age, incidental learning correlated significantly with the CVLT-II Immediate Free Recall, CVLT-II Short-Delay Recall, CVLT-II Long-Delay Recall, and CVLT-II Yes/No Recognition Hits, and with the BVMT-R Delayed Recall and BVMT-R Recognition Discrimination Index. Our incidental learning procedures derived from subtests of the WAIS-IV Edition are an efficient and valid way of measuring memory. These tasks add minimally to testing time and capitalize on the semantic encoding that is inherent in completing the Similarities and Vocabulary subtests.

African Ancestry Gradient Is Associated with Lower Systemic F2-Isoprostane Levels.

PubMed

Annor, Francis; Goodman, Michael; Thyagarajan, Bharat; Okosun, Ike; Doumatey, Ayo; Gower, Barbara A; Il'yasova, Dora

2017-01-01

Context . Low levels of systemic F 2 -isoprostanes (F 2 -IsoP) increase the risk of diabetes and weight gain and were found in African Americans. Low F 2 -IsoPs could reflect an unfavorable metabolic characteristic, namely, slow mitochondrial metabolism in individuals with African ancestry. Objective . To examine differences in plasma F 2 -IsoPs in three groups with a priori different proportion of African ancestry: non-Hispanic Whites (NHWs), US-born African Americans (AAs), and West African immigrants (WAI). Design . Cross-sectional study. Setting . Georgia residents recruited from church communities. Participants . 218 males and females 25-74 years of age, who are self-identified as NHW ( n = 83), AA ( n = 56), or WAI ( n = 79). Main Outcome Measure(s) . Plasma F 2 -IsoPs quantified by gas chromatography-mass spectrometry. Results . After adjustment for age, gender, obesity, and other comorbidities, WAI had lower levels of plasma F 2 -IsoP than AA (beta-coefficient = -9.8, p < 0.001) and AA had lower levels than NHW (beta-coefficient = -30.3, p < 0.001). Similarly, among healthy nonobese participants, F 2 -IsoP levels were lowest among WAI, followed by AA, and the highest levels were among NHW. Conclusion . Plasma F 2 -IsoPs are inversely associated with African ancestry gradient. Additional studies are required to test whether optimization of systemic F 2 -IsoP levels can serve as means to improve race-specific lifestyle and pharmacological intervention targeted to obesity prevention and treatment.

WAIS Searching of the Current Contents Database

NASA Astrophysics Data System (ADS)

Banholzer, P.; Grabenstein, M. E.

The Homer E. Newell Memorial Library of NASA's Goddard Space Flight Center is developing capabilities to permit Goddard personnel to access electronic resources of the Library via the Internet. The Library's support services contractor, Maxima Corporation, and their subcontractor, SANAD Support Technologies have recently developed a World Wide Web Home Page (http://www-library.gsfc.nasa.gov) to provide the primary means of access. The first searchable database to be made available through the HomePage to Goddard employees is Current Contents, from the Institute for Scientific Information (ISI). The initial implementation includes coverage of articles from the last few months of 1992 to present. These records are augmented with abstracts and references, and often are more robust than equivalent records in bibliographic databases that currently serve the astronomical community. Maxima/SANAD selected Wais Incorporated's WAIS product with which to build the interface to Current Contents. This system allows access from Macintosh, IBM PC, and Unix hosts, which is an important feature for Goddard's multiplatform environment. The forms interface is structured to allow both fielded (author, article title, journal name, id number, keyword, subject term, and citation) and unfielded WAIS searches. The system allows a user to: Retrieve individual journal article records. Retrieve Table of Contents of specific issues of journals. Connect to articles with similar subject terms or keywords. Connect to other issues of the same journal in the same year. Browse journal issues from an alphabetical list of indexed journal names.

The HSE indicator tool, psychological distress and work ability.

PubMed

Guidi, S; Bagnara, S; Fichera, G P

2012-04-01

The Health and Safety Executive (HSE) indicator tool is one of the most commonly used tools for assessing the risk of work-related stress. Few studies, however, have investigated whether and how its scales are related to psychological distress or other work-related health outcomes. To investigate the relationship between the HSE indicator tool, psychological distress, as measured by the General Health Questionnaire (GHQ)-12, and work ability, assessed by the Work Ability Index (WAI). All the employees of a mid-sized bank in Italy were asked to fill in an anonymous cross-sectional questionnaire. The questionnaire was structured in four sections: the first one comprised socio-demographic questions and the other three corresponded, respectively, to the Italian translations of the GHQ-12, the HSE and the WAI questionnaires. Four hundred and thirteen employees completed the questionnaire. The response rate was 99%. Controlling for age and gender, the indicator subscales were negatively associated with the adopted measures of psychological distress and work ability. The GHQ score was also highly correlated with the WAI score and able to explain ≈ 47% of its variance. The only subscale that was still significantly associated with the WAI after removing the effect of psychological distress was 'control'. The study presents new evidence for the validity of the HSE indicator tool to estimate the risk of work-related stress and suggests that most but not all the effects of psychosocial conditions on work ability might be mediated by the level of psychological distress induced by these conditions.

STELAR: An experiment in the electronic distribution of astronomical literature

NASA Technical Reports Server (NTRS)

Warnock, A.; Vansteenburg, M. E.; Brotzman, L. E.; Gass, J.; Kovalsky, D.

1992-01-01

STELAR (Study of Electronic Literature for Astronomical Research) is a Goddard-based project designed to test methods of delivering technical literature in machine readable form. To that end, we have scanned a five year span of the ApJ, ApJ Supp, AJ and PASP, and have obtained abstracts for eight leading academic journals from NASA/STI CASI, which also makes these abstracts available through the NASA RECON system. We have also obtained machine readable versions of some journal volumes from the publishers, although in many instances, the final typeset versions are no longer available. The fundamental data object for the STELAR database is the article, a collection of items associated with a scientific paper - abstract, scanned pages (in a variety of formats), figures, OCR extractions, forward and backward references, errata and versions of the paper in various formats (e.g., TEX, SGML, PostScript, DVI). Articles are uniquely referenced in the database by journal name, volume number and page number. The selection and delivery of articles is accomplished through the WAIS (Wide Area Information Server) client/server models requiring only an Internet connection. Modest modifications to the server code have made it capable of delivering the multiple data types required by STELAR. WAIS is a platform independent and fully open multi-disciplinary delivery system, originally developed by Thinking Machines Corp. and made available free of charge. It is based on the ISO Z39.50 standard communications protocol. WAIS servers run under both UNIX and VMS. WAIS clients run on a wide variety of machines, from UNIX-based Xwindows systems to MS-DOS and macintosh microcomputers. The WAIS system includes full-test indexing and searching of documents, network interface and easy access to a variety of document viewers. ASCII versions of the CASI abstracts have been formatted for display and the full test of the abstracts has been indexed. The entire WAIS database of abstracts is now available for use by the astronomical community. Enhancements of the search and retrieval system are under investigation to include specialized searches (by reference, author or keyword, as opposed to full test searches), improved handling of word stems, improvements in relevancy criteria and other retrieval techniques, such as factor spaces. The STELAR project has been assisted by the full cooperation of the AAS, the ASP, the publishers of the academic journals, librarians from GSFC, NRAO and STScI, the Library of Congress, and the University of North Carolina at Chapel Hill.

CT manifestations of peritoneal carcinomatosis.

PubMed

Walkey, M M; Friedman, A C; Sohotra, P; Radecki, P D

1988-05-01

Seventy-three abdominopelvic contrast-enhanced CT scans obtained in 60 patients with peritoneal tumor spread were reviewed retrospectively to determine the CT signs of peritoneal malignancy. Ascites was present in 54 studies (74%) and was the most common CT finding. Loculation of the fluid occurred in 25 (46%) of these. In nine (17%) of the 54, a new finding, absence of cul-de-sac fluid in the presence of generalized ascites, was noted. Parietal peritoneal thickening with contrast enhancement of the peritoneum, making the peritoneum visible as a thin line along the abdominal wall, was present in 45 (62%) of studies. This is believed to represent confluent peritoneal metastases. Small-bowel involvement was present in half of the cases (wall thickening and irregularity with or without obstruction). Tumor involvement of the omentum was visible as soft-tissue permeation of fat, enhancing nodules, and/or an omental cake. Of the 26 patients without a previously known malignancy, identification of the primary tumor in addition to peritoneal carcinomatosis was possible in 13 (50%). Appreciation of the spectrum of CT findings in peritoneal carcinomatosis is essential for accurate evaluation of scans in patients with abdominopelvic malignancies.

Clinical and computed tomography features of adult abdominopelvic desmoplastic small round cell tumor.

PubMed

Shen, Xun-Ze; Zhao, Jian-Guo; Wu, Jian-Jun; Liu, Fang

2014-05-07

To investigate the clinical and computed tomography (CT) features of desmoplastic small round cell tumor (DSRCT), we retrospectively analyzed the clinical presentations, treatment and outcome, as well as CT manifestations of four cases of DSRCT confirmed by surgery and pathology. The CT manifestations of DSRCT were as follows: (1) multiple soft-tissue masses or diffuse peritoneal thickening in the abdomen and pelvis, with the dominant mass usually located in the pelvic cavity; (2) masses without an apparent organ-based primary site; (3) mild to moderate homogeneous or heterogeneous enhancement in solid area on enhanced CT; and (4) secondary manifestations, such as ascites, hepatic metastases, lymphadenopathy, hydronephrosis and hydroureter. The prognosis and overall survival rates were generally poor. Commonly used treatment strategies including aggressive tumor resection, polychemotherapy, and radiotherapy, showed various therapeutic effects. CT of DSRCT shows characteristic features that are helpful in diagnosis. Early discovery and complete resection, coupled with postoperative adjuvant chemotherapy, are important for prognosis of DSRCT. Whole abdominopelvic rather than locoregional radiotherapy is more effective for unresectable DSRCT.

Effect of abdominopelvic abscess drain size on drainage time and probability of occlusion.

PubMed

Rotman, Jessica A; Getrajdman, George I; Maybody, Majid; Erinjeri, Joseph P; Yarmohammadi, Hooman; Sofocleous, Constantinos T; Solomon, Stephen B; Boas, F Edward

2017-04-01

The purpose of this study is to determine whether larger abdominopelvic abscess drains reduce the time required for abscess resolution or the probability of tube occlusion. 144 consecutive patients who underwent abscess drainage at a single institution were reviewed retrospectively. Larger initial drain size did not reduce drainage time, drain occlusion, or drain exchanges (P > .05). Subgroup analysis did not find any type of collection that benefitted from larger drains. A multivariate model predicting drainage time showed that large collections (>200 mL) required 16 days longer drainage time than small collections (<50 mL). Collections with a fistula to bowel required 17 days longer drainage time than collections without a fistula. Initial drain size and the viscosity of the fluid in the collection had no significant effect on drainage time in the multivariate model. 8 F drains are adequate for initial drainage of most serous and serosanguineous collections. 10 F drains are adequate for initial drainage of most purulent or bloody collections. Copyright © 2016 Elsevier Inc. All rights reserved.

Pediatric Chest and Abdominopelvic CT: Organ Dose Estimation Based on 42 Patient Models

PubMed Central

Tian, Xiaoyu; Li, Xiang; Segars, W. Paul; Paulson, Erik K.; Frush, Donald P.

2014-01-01

Purpose To estimate organ dose from pediatric chest and abdominopelvic computed tomography (CT) examinations and evaluate the dependency of organ dose coefficients on patient size and CT scanner models. Materials and Methods The institutional review board approved this HIPAA–compliant study and did not require informed patient consent. A validated Monte Carlo program was used to perform simulations in 42 pediatric patient models (age range, 0–16 years; weight range, 2–80 kg; 24 boys, 18 girls). Multidetector CT scanners were modeled on those from two commercial manufacturers (LightSpeed VCT, GE Healthcare, Waukesha, Wis; SOMATOM Definition Flash, Siemens Healthcare, Forchheim, Germany). Organ doses were estimated for each patient model for routine chest and abdominopelvic examinations and were normalized by volume CT dose index (CTDIvol). The relationships between CTDIvol-normalized organ dose coefficients and average patient diameters were evaluated across scanner models. Results For organs within the image coverage, CTDIvol-normalized organ dose coefficients largely showed a strong exponential relationship with the average patient diameter (R2 > 0.9). The average percentage differences between the two scanner models were generally within 10%. For distributed organs and organs on the periphery of or outside the image coverage, the differences were generally larger (average, 3%–32%) mainly because of the effect of overranging. Conclusion It is feasible to estimate patient-specific organ dose for a given examination with the knowledge of patient size and the CTDIvol. These CTDIvol-normalized organ dose coefficients enable one to readily estimate patient-specific organ dose for pediatric patients in clinical settings. This dose information, and, as appropriate, attendant risk estimations, can provide more substantive information for the individual patient for both clinical and research applications and can yield more expansive information on dose profiles across patient populations within a practice. © RSNA, 2013 PMID:24126364

The role of radiotherapy in the treatment of carcinoma of the prostate: a survey of clinical practices in Lombardy, Italy, by the AIRO-Lombardia Cooperative Group. Italian Association for Radiation Oncology.

PubMed

Villa, S; Bertoni, F; Bossi, A; Caraffini, B; Corbella, F; Di Lorenzo, I; Italia, C; Leoni, M; Nava, S; Sarti, E; Vavassori, V; Villa, E; Palazzi, M

1998-01-01

We report the results of a survey performed in 1994 by the AIRO-Lombardia Cooperative Group, on the clinical patterns of radiation treatment for prostatic carcinoma in Lombardy, Italy, involving all radiotherapy centers serving an overall local population of about 8,800,000 people. A questionnaire was sent to all 13 radiotherapy centers throughout Lombardy, asking for demographic and treatment details concerning the local population of patients with a localized (T1-4, N0-1, M0) carcinoma of the prostate treated with radiotherapy; 12 centers responded, making the basis for the present report. Analysis of collected data showed that in Lombardy: a) approximately 400 patients per year are irradiated for a localized carcinoma of the prostate, accounting for less than 30% of the total expected number of patients with this disease presentation; b) a complete staging (with PSA, transrectal ultrasonography, abdomino-pelvic CT or MRI scan and total-body bone scan) is performed in over 95% of patients before initiating radiotherapy; c) significant differences exist between radiotherapy centers as regards treatment planning and delivery. An urgent need exists for implementing procedures aimed at standardizing radiotherapy procedures within Lombardy.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lubin, D; Bromwich, DH; Russell, LM

West Antarctica is one of the most rapidly warming regions on Earth, and this warming is closely connected with global sea level rise. The discovery of rapid climate change on the West Antarctic Ice Sheet (WAIS) has challenged previous explanations of Antarctic climate change that focused on strengthening of circumpolar westerlies in response to the positive polarity trend in the Southern Annular Mode. West Antarctic warming does not yet have a comprehensive explanation: dynamical mechanisms may vary from one season to the next, and these mechanisms very likely involve complex teleconnections with subtropical and tropical latitudes. The prime motivation formore » this proposal is that there has been no substantial atmospheric science or climatological field work on West Antarctica since the 1957 International Geophysical Year and that research continued for only a few years. Direct meteorological information on the WAIS has been limited to a few automatic weather stations for several decades, yet satellite imagery and meteorological reanalyses indicate that West Antarctica is highly susceptible to advection of warm and moist maritime air with related cloud cover, depending on the location and strength of low pressure cells in the Amundsen, Ross, and Bellingshausen Seas. There is a need to quantify the role of these changing air masses on the surface energy balance, including all surface energy components and cloud-radiative forcing. More generally, global climate model simulations are known to perform poorly over the Antarctic and Southern Oceans, and the marked scarcity of cloud information at southern high latitudes has so far inhibited significant progress. Fortunately, McMurdo Station, where the Atmospheric Radiation Measurement Facility’s (ARM’s) most advanced cloud and aerosol instrumentation is situated, has a meteorological relationship with the WAIS via circulation patterns in the Ross and Amundsen Seas. We can therefore gather sophisticated data with cloud radars and high spectral resolution lidar and a complete aerosol suite at McMurdo that have relevance to the WAIS as well. At the same time, we will send basic radiometric, surface energy balance, and upper air equipment directly to the WAIS to make the first well calibrated climatological suite of measurements seen in this extremely remote but globally critical region in more than 40 years.« less

Work ability of Chinese migrant workers: the influence of migration characteristics.

PubMed

Han, Lu; Shi, Leiyu; Lu, Liming; Ling, Li

2014-04-13

Migrant workers have become a vital labor supply to China's economy. Their migration process and work conditions may influence their health and work ability. The work ability of migrant workers in China and the influence of the migration process on work ability have not been explored extensively in previous studies. The objective of this study is to evaluate the association of migration characteristics and work-related factors with work ability among migrant workers in the Pearl River Delta. In this cross-sectional survey, the study population consisted of 907 migrant workers from ten factories in the Pearl River Delta who were exposed to organic solvents during work. The primary dependent variable of the study was work ability, measured by the Work Ability Index (WAI). The independent variables were individual characteristics, migration characteristics, and work-related factors. Logistic regression models were used to determine the influence of different factors on work ability and three dimensions of WAI. The result shows that among migration characteristics, social support was significantly associated with all three dimensions of the work ability index. Permanent migration intention and longer length of migration were negatively associated with the mental resource dimension of WAI. WAI was also influenced by individual and work-related factors. The findings of this study suggest that expanding migrants' social networks and social support systems in their work place or living community, (i.e. expanding the functions of labor unions) would be an effective way to improve migrant workers' work ability. Improving of migrant workers' physical and psychosocial related work environments would also increase their work ability.

Reciprocal empathy and working alliance in terminal oncological illness: the crucial role of patients' attachment style.

PubMed

Calvo, Vincenzo; Palmieri, Arianna; Marinelli, Sara; Bianco, Francesca; Kleinbub, Johann R

2014-01-01

Security of attachment is described as an inner resource that may also facilitate the adaptation of individuals during critical life adversity, even when facing end-stage illness and death. This study assessed the relation between attachment styles, patient-caregiver reciprocal empathy, and patient-physician working alliance, in the terminal phase of an oncological disease. We hypothesized that the attachment security of patients, as measured by the Relationship Questionnaire (RQ), is related to the reciprocal empathy with the caregiver, as measured by the Perception of Partner Empathy (PPE) questionnaire, and to the working alliance with the physician, as measured by the Working Alliance Inventory-Short Form (WAI-S). Thirty-seven end-stage cancer patients, their caregivers, and physicians participated in the study. The PPE and WAI-S were administered twice: immediately after the hospice recovery and a week later. Results showed a significant improvement in patient-caregiver empathy and in patient-physician alliance after a week at the hospice. Findings indicated that the patients' attachment style influenced their perception of reciprocal empathy with the caregiver and the working alliance with the physician. Patients with a secure attachment had a greater capacity to show empathic closeness with their caregivers and enjoyed a better working alliance with their physicians. Caregivers' attachment security, otherwise, did not show the same influence on empathy and alliance. Findings support the hypothesis that patients' attachment security plays a crucial role in the relation with their own caregiver and with the physician, even at the terminal phase. Theoretical and clinical implications of these findings are explored in the discussion.

The Alliance Negotiation Scale: A psychometric investigation.

PubMed

Doran, Jennifer M; Safran, Jeremy D; Muran, J Christopher

2016-08-01

This study investigates the utility and psychometric properties of a new measure of psychotherapy process, the Alliance Negotiation Scale (ANS; Doran, Safran, Waizmann, Bolger, & Muran, 2012). The ANS was designed to operationalize the theoretical construct of negotiation (Safran & Muran, 2000), and to extend our current understanding of the working alliance concept (Bordin, 1979). The ANS was also intended to improve upon existing measures such as the Working Alliance Inventory (WAI; Horvath & Greenberg, 1986, 1989) and its short form (WAI-S; Tracey & Kokotovic, 1989) by expanding the emphasis on negative therapy process. The present study investigates the psychometric validity of the ANS test scores and interpretation-including confirming its original factor structure and evaluating its internal consistency and construct validity. Construct validity was examined through the ANS' convergence and divergence with several existing scales that measure theoretically related constructs. The results bolster and extend previous findings about the psychometric integrity of the ANS, and begin to illuminate the relationship between negotiation and other important variables in psychotherapy research. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Effects of major depression on estimates of intelligence.

PubMed

Sackeim, H A; Freeman, J; McElhiney, M; Coleman, E; Prudic, J; Devanand, D P

1992-03-01

This study examined whether patients with major depressive disorder manifest deficits in intelligence during affective episodes and following clinical improvement. WAIS-R scores were contrasted in 100 patients in an episode of major depression with 50 normal controls, matched to the patient sample in terms of demographic variables and estimates of premorbid IQ. The groups were equivalent in verbal IQ, but, in line with previous studies, the depressed patients had a pronounced deficit in performance IQ. A patient subsample was administered the WAIS-R under unlimited time conditions to determine whether the time constraints of performance IQ subtests contributed to the magnitude of the verbal-performance IQ discrepancy. This discrepancy was only slightly reduced with untimed scoring. Subgroups of depressed patients were retested with the WAIS-R within one week (n = 26) or two months (n = 33) following treatment with electroconvulsive therapy. In both subsamples, IQ scores were improved at posttreatment testing relative to pretreatment, but with little change in the verbal-performance IQ discrepancy. These and related findings suggested that a performance IQ deficit is characteristic of depressed patients regardless of affective state.

Dyadic Short Forms of the Wechsler Adult Intelligence Scale-IV.

PubMed

Denney, David A; Ringe, Wendy K; Lacritz, Laura H

2015-08-01

Full Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) administration can be time-consuming and may not be necessary when intelligence quotient estimates will suffice. Estimated Full Scale Intelligence Quotient (FSIQ) and General Ability Index (GAI) scores were derived from nine dyadic short forms using individual regression equations based on data from a clinical sample (n = 113) that was then cross validated in a separate clinical sample (n = 50). Derived scores accounted for 70%-83% of the variance in FSIQ and 77%-88% of the variance in GAI. Predicted FSIQs were strongly associated with actual FSIQ (rs = .73-.88), as were predicted and actual GAIs (rs = .80-.93). Each of the nine dyadic short forms of the WAIS-IV was a good predictor of FSIQ and GAI in the validation sample. These data support the validity of WAIS-IV short forms when time is limited or lengthier batteries cannot be tolerated by patients. © The Author 2015. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Comparing Canadian and American normative scores on the Wechsler Adult Intelligence Scale-Fourth Edition.

PubMed

Harrison, Allyson G; Armstrong, Irene T; Harrison, Laura E; Lange, Rael T; Iverson, Grant L

2014-12-01

Psychologists practicing in Canada must decide which set of normative data to use for the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV). The purpose of this study was to compare the interpretive effects of applying American versus Canadian normative systems in a sample of 432 Canadian postsecondary-level students who were administered the WAIS-IV as part of an evaluation for a learning disability, attention-deficit hyperactivity disorder, or other mental health problems. Employing the Canadian normative system yielded IQ, Index, and subtest scores that were systematically lower than those obtained using the American norms. Furthermore, the percentage agreement in normative classifications, defined as American and Canadian index scores within five points or within the same classification range, was between 49% and 76%. Substantial differences are present between the American and Canadian WAIS-IV norms. Clinicians should consider carefully the implications regarding which normative system is most appropriate for specific types of evaluations. © The Author 2014. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Work-related stress and work ability among Croatian university hospital midwives.

PubMed

Knezevic, Bojana; Milosevic, Milan; Golubic, Rajna; Belosevic, Ljiljana; Russo, Andrea; Mustajbegovic, Jadranka

2011-04-01

to explore the sources and levels of stress at work and work ability among Croatian midwives. midwives are subjected to multiple stressors. Among health-care professionals, psychological distress for a prolonged period of time has negative effects on the worker's health, work ability and quality of patient care. 'Work ability' is a term describing a worker's resources related to physical, mental and social demands at work. As a measure of work ability in midwifery, the Work Ability Index (WAI) is considered to be a very predictive instrument; midwives with a poor WAI score usually leave their current job within five years. university hospitals in Zagreb, Croatia. cross-sectional design survey. 300 health-care workers (105 qualified midwives and 195 paediatric nurses) were invited to complete the questionnaire. The total response rate was 53% (158/300). The sample included 14.7% of all hospital-based midwives in Zagreb hospitals. the Occupational Stress Assessment Questionnaire (OSAQ) for health-care workers and the WAI questionnaire. over three-quarters of the midwives (46/60, 76.7%) believed that their job was stressful, and considered that insufficient work resources caused the most stress. More than half of the midwives associated an insufficient number of coworkers, unexpected situations, inadequate income, night work, incurable patients and poor organisation at work with a high level of stress. The perceived specific stressors differed between midwives and paediatric nurses in the same hospital. Insufficient work resources and poor organisation at work were more common stressors among midwives than paediatric nurses (p<0.05). Midwives and nurses differed significantly with respect to age (p=0.002). Midwives were younger and had spent fewer years working in their current workplace compared with paediatric nurses (p<0.001). Also, midwives had a lower level of education than paediatric nurses (p=0.044). The mean WAI score for midwives was 40.0 [95% confidence interval (CI) 38.4-41.4], compared with 37.5 (95% CI 36.4-38.8) for paediatric nurses, both indicating good work ability. After adjusting for age, the difference in WAI score between the groups of workers was not significant. Croatian midwives experienced work-related stress due to: insufficient work resources, insufficient number of coworkers, poor organisation at work, communication with superiors and emotional work. Midwives' work ability in relation to the demands of their job was good. These results confirmed that the WAI score decreases significantly with age. hospital management needs to improve organisational factors and resources, as well as midwives' education and position in the health-care system. Copyright © 2009 Elsevier Ltd. All rights reserved.

Acceptability of oral iodinated contrast media: a head-to-head comparison of four media.

PubMed

Pollentine, A; Ngan-Soo, E; McCoubrie, P

2013-05-01

To assess the palatability of iodinated oral contrast media commonly used in abdominopelvic CT and CT colonography (CTC). 80 volunteers assessed the palatability of a 20-ml sample of a standard 30 mg ml(-1) dilution of Omnipaque® (iohexol; GE Healthcare, Cork, Ireland), Telebrix® (meglumine ioxithalamate; Guerbet, Aulnay-sous-Bois, France), Gastromiro® (iopamidol; Bracco, High Wycombe, UK) and Gastrografin® (sodium diatrizoate and meglumine diatrizoate; Bayer, Newbury, UK) in a computer-generated random order. Gastrografin is rated significantly less palatable than the remaining media (p<0.005). Omnipaque and Telebrix are significantly more palatable than Gastromiro. No difference existed between Omnipaque and Telebrix. 39% of participants would refuse to consume the quantities of Gastrografin required for a CTC examination compared with Telebrix (7%) and Omnipaque (9%) (p<0.05). Omnipaque and Telebrix are significantly more palatable than both Gastromiro and Gastrografin, with participants more willing to ingest them in larger quantities as well as being less expensive. Omnipaque and Telebrix are significantly more palatable iodinated oral contrast media than both Gastromiro and Gastrografin, which has potential implications in compliance with both abdominopelvic CT and CTC.

Acceptability of oral iodinated contrast media: a head-to-head comparison of four media

PubMed Central

Ngan-Soo, E; McCoubrie, P

2013-01-01

Objective: To assess the palatability of iodinated oral contrast media commonly used in abdominopelvic CT and CT colonography (CTC). Methods: 80 volunteers assessed the palatability of a 20-ml sample of a standard 30 mg ml−1 dilution of Omnipaque® (iohexol; GE Healthcare, Cork, Ireland), Telebrix® (meglumine ioxithalamate; Guerbet, Aulnay-sous-Bois, France), Gastromiro® (iopamidol; Bracco, High Wycombe, UK) and Gastrografin® (sodium diatrizoate and meglumine diatrizoate; Bayer, Newbury, UK) in a computer-generated random order. Results: Gastrografin is rated significantly less palatable than the remaining media (p<0.005). Omnipaque and Telebrix are significantly more palatable than Gastromiro. No difference existed between Omnipaque and Telebrix. 39% of participants would refuse to consume the quantities of Gastrografin required for a CTC examination compared with Telebrix (7%) and Omnipaque (9%) (p<0.05). Conclusion: Omnipaque and Telebrix are significantly more palatable than both Gastromiro and Gastrografin, with participants more willing to ingest them in larger quantities as well as being less expensive. Advances in knowledge: Omnipaque and Telebrix are significantly more palatable iodinated oral contrast media than both Gastromiro and Gastrografin, which has potential implications in compliance with both abdominopelvic CT and CTC. PMID:23564884

Oceanic an climatic consequences of a sudden large-scale West Antarctic Ice Sheet collapse

NASA Astrophysics Data System (ADS)

Scarff, Katie; Green, Mattias; Schmittner, Andreas

2015-04-01

Atmospheric warming is progressing to the point where the West Antarctic Ice Sheet (WAIS) will experience an elevated rate of discharge. The current discharge rate of WAIS is around 0.005Sv, but this rate will most likely accelerate over this century. The input of freshwater, in the form of ice, may have a profound effect on oceanic circulation systems, including potentially reducing the formation of deep water in the Southern Ocean and thus triggering or enhancing the bipolar seesaw. Using UVic - an intermediate complexity ocean-climate model - we investigate how various hosing rates from the WAIS will impact of the present and future ocean circulation and climate. These scenarios range from observed hosing rates (~0.005Sv) being applied for 100 years, to a total collapse of the WAIS over the next 100 years (the equivalent to a0.7Sv hosing). We show that even the present day observed rates can have a significant impact on the ocean and atmospheric temperatures, and that the bipolar seesaw may indeed be enhanced by the Southern Ocean hosing. Consequently, there is a speed-up of the Meridional Overturning Circulation (MOC) early on during the hosing, which leads to a warming over the North Atlantic, and a subsequent reduction in the MOC on centennial scales. The larger hosing cases show more dramatic effects with near-complete shutdowns of the MOC during the hosing. Furthermore, global warming scenarios based on the IPCC "business as usual" scenario show that the atmospheric warming will change the response of the ocean to Southern Ocean hosing and that the warming will dominate the perturbation. The potential feedback between changes in the ocean stratification in the scenarios and tidally driven abyssal mixing via tidal conversion is also explored.

The effect of middle ear cavity and superior canal dehiscence on wideband acoustic immittance in fresh human cadaveric specimens

NASA Astrophysics Data System (ADS)

Masud, Salwa F.; Raufer, Stefan; Neely, Stephen T.; Nakajima, Hideko H.

2018-05-01

Superior canal dehiscence (SCD) is a hole in the bony wall of the superior semicircular canal, which can cause various auditory and/or vestibular symptoms and can result in wrong and/or delayed diagnosis. Wideband acoustic immittance (WAI) can potentially distinguish various mechanical middle-ear pathologies as well as inner-ear pathologies non-invasively. We found that in patients, SCD was commonly associated with a narrow-band decrease in power reflectance (PR, derived from WAI) near 1 kHz. Because clinical data has large variation across individual ears and because we do not know the individual "normal" state prior to SCD, we measured WAI in five fresh temporal bone specimens to determine the effects of SCD with respect to the normal state. In temporal bone, we measured PR to assess mechanical changes before and after SCD, as well as to assess the effect of an open or closed middle-ear cavity. After SCD, PR had a consistent decrease between 0.48 and 0.76 kHz, and a slight increase between 1.04 and 1.4 kHz in the open cavity condition. However, in several experiments, we observed low PR around 1 kHz in the normal state before SCD, likely due to the specimen's open middle ear cavity (MEC). Because we see effects of both SCD and open MEC around 1 kHz, some of the SCD effect can be masked by the effect of the MEC in the temporal bone specimens. To compensate for this MEC effect, we estimated the effect of SCD in a closed MEC case, but the effect did not differ significantly from the measured open MEC. This study demonstrates the limitation of temporal bone experiments with open MEC when studying inner-ear lesions with WAI.

The Preservation and Recycling of Snow Pack Nitrate at the West Antarctic Ice Sheet (WAIS) Divide Ice Core Site from the Present Day to the Last Glacial Period.

NASA Astrophysics Data System (ADS)

Robinson, J. W.; Buffen, A.; Hastings, M. G.; Schauer, A. J.; Moore, L.; Isaacs, A.; Geng, L.; Savarino, J. P.; Alexander, B.

2017-12-01

We use observations of the nitrogen isotopic composition of nitrate (δ15N(NO3-)) from snow and ice collected at the West Antarctic ice sheet (WAIS) divide ice core site to quantify the preservation and recycling of snow nitrate. Ice-core samples cover a continuous section from 36 to 52 thousand years ago and discrete samples from the Holocene, the last glacial maximum (LGM), and the glacial-Holocene transition. Higher δ15N of nitrate is consistently associated with lower temperatures with δ15N(NO3-) varying from 26 to 45 ‰ during the last glacial period and from 1 to 45 ‰ between the Holocene and glacial periods, respectively. We attribute the higher δ15N in colder periods to lower snow accumulation rates which lead to greater loss of snow nitrate via photolysis before burial beneath the snow photic zone. Modeling of nitrate preservation in snow pack was performed for modern and LGM conditions. The model is used in conjunction with observations to estimate the fraction of snow nitrate that is photolyzed, re-oxidized, and re-deposited over WAIS divide versus the fraction of primary nitrate that is deposited via long range transport. We used these estimates of fractional loss of snow nitrate in different time periods to determine the variation in the deposition flux of primary nitrate at WAIS divide with climate. Our findings have implications for the climate sensitivity of the oxidizing capacity of the polar atmosphere and the interpretation of ice-core records of nitrate in terms of past atmospheric composition.

Decrease in Work Ability Index and sickness absence during the following year: a two-year follow-up study.

PubMed

Ohta, Masanori; Higuchi, Yoshiyuki; Kumashiro, Masaharu; Yamato, Hiroshi; Sugimura, Hisamichi

2017-11-01

Using a 2-year follow-up design, we examined whether changes in work ability during 1 year predicted sickness absence in the following year. Workers (N = 1408) from the Japanese information technology sector each completed the Work Ability Index (WAI), the Brief Job Stress Questionnaire (BJSQ), and the General Health Questionnaire (GHQ) in 2011 and 2012. Absence data during 2013 was obtained from employees' computerized attendance records. We used psychological distress as evaluated by the GHQ; job stress and job support calculated using the BJSQ; and job title, sex, and age as potential confounding variables. Thirty-five employees had at least one sickness absence lasting more than seven consecutive days in 2013. Forty-nine percent of sickness absences were due to mental illness, and the others were due to orthopedic disease (20%), cancer (9%), and other illnesses (23%). Decrease in WAI scores from 2011 to 2012 predicted sickness absence in 2013 (Odds ratio (OR) 1.19, 95% confidence interval (CI) 1.12-1.27). This association remained unaltered after adjusting for sex, age, job title, WAI score from the year before, job stress, job support, and GHQ score (OR 1.15, 95% CI 1.06-1.25). We analyzed this association separately by reason for absence: mental or other illness. WAI score decreases predicted sickness absence for both reasons (OR for mental illness 1.24, 95% CI 1.14-1.36; OR for other illnesses 1.14, 95% CI 1.04-1.24). Decrease in work ability during the year predicts sickness absence in the following year while predictive power was weak.

Revisiting measurement invariance in intelligence testing in aging research: Evidence for almost complete metric invariance across age groups.

PubMed

Sprague, Briana N; Hyun, Jinshil; Molenaar, Peter C M

2017-01-01

Invariance of intelligence across age is often assumed but infrequently explicitly tested. Horn and McArdle (1992) tested measurement invariance of intelligence, providing adequate model fit but might not consider all relevant aspects such as sub-test differences. The goal of the current paper is to explore age-related invariance of the WAIS-R using an alternative model that allows direct tests of age on WAIS-R subtests. Cross-sectional data on 940 participants aged 16-75 from the WAIS-R normative values were used. Subtests examined were information, comprehension, similarities, vocabulary, picture completion, block design, picture arrangement, and object assembly. The two intelligence factors considered were fluid and crystallized intelligence. Self-reported ages were divided into young (16-22, n = 300), adult (29-39, n = 275), middle (40-60, n = 205), and older (61-75, n = 160) adult groups. Results suggested partial metric invariance holds. Although most of the subtests reflected fluid and crystalized intelligence similarly across different ages, invariance did not hold for block design on fluid intelligence and picture arrangement on crystallized intelligence for older adults. Additionally, there was evidence of a correlated residual between information and vocabulary for the young adults only. This partial metric invariance model yielded acceptable model fit compared to previously-proposed invariance models of Horn and McArdle (1992). Almost complete metric invariance holds for a two-factor model of intelligence. Most of the subtests were invariant across age groups, suggesting little evidence for age-related bias in the WAIS-R. However, we did find unique relationships between two subtests and intelligence. Future studies should examine age-related differences in subtests when testing measurement invariance in intelligence.

Transcranial Direct Current Stimulation of Frontal Cortex Decreases Performance on the WAIS-IV Intelligence Test

PubMed Central

Sellers, Kristin K.; Mellin, Juliann M.; Lustenberger, Caroline M.; Boyle, Michael R.; Lee, Won Hee; Peterchev, Angel V.; Frohlich, Flavio

2015-01-01

Transcranial direct current stimulation (tDCS) modulates excitability of motor cortex. However, there is conflicting evidence about the efficacy of this non-invasive brain stimulation modality to modulate performance on cognitive tasks. Previous work has tested the effect of tDCS on specific facets of cognition and executive processing. However, no randomized, double-blind, sham-controlled study has looked at the effects of tDCS on a comprehensive battery of cognitive processes. The objective of this study was to test if tDCS had an effect on performance on a comprehensive assay of cognitive processes, a standardized intelligence quotient (IQ) test. The study consisted of two substudies and followed a double-blind, between-subjects, sham-controlled design. In total, 41 healthy adult participants completed the Wechsler Adult Intelligence Scale, Fourth Edition (WAIS-IV) as a baseline measure. At least one week later, participants in substudy 1 received either bilateral tDCS (anodes over both F4 and F3, cathode over Cz, 2mA at each anode for 20 minutes) or active sham tDCS (2mA for 40 seconds), and participants in substudy 2 received either right or left tDCS (anode over either F4 or F3, cathode over Cz, 2mA for 20 minutes). In both studies, the WAIS-IV was immediately administered following stimulation to assess for performance differences induced by bilateral and unilateral tDCS. Compared to sham stimulation, right, left, and bilateral tDCS reduced improvement between sessions on Full Scale IQ and the Perceptual Reasoning Index. This demonstration that frontal tDCS selectively degraded improvement on specific metrics of the WAIS-IV raises important questions about the often proposed role of tDCS in cognitive enhancement. PMID:25934490

Quality of life, work ability and other important indicators of women's occupational health.

PubMed

Tavakoli-Fard, Negah; Mortazavi, Seyed-Alireza; Kuhpayehzadeh, Jalil; Nojomi, Marzieh

2016-01-01

Work ability may be considered as an important aspect of well-being and health status. One of the most important factors in association with work ability is health-related quality of life (HRQoL). The aim of this study has been to determine the association between work ability, individual characteristics and HRQoL of female workers. The design of this study has been cross-sectional. The work ability index (WAI) and Short-Form General Health Survey (SF-12) questionnaires were used to collect data. Three hundred and twenty female workers were selected from food supplier factories in Karaj. One-way analysis of variance, Pearson's correlation analysis, independent sample t-test and multiple linear regression methods were used to analyze data. Mean (M) and standard deviation (SD) of the WAI stood at 35.02 and 5.57, respectively. The categories of the WAI for women being as follows: 8.8% poor, 62% moderate, 25.4% good and 3.7% excellent. Mean±SD for the physical component summary (PCS) and mental component summary (MCS) of quality of life was 58.84±11.12 and 57.45±9.94, respectively. There was a positive significant association between the PCS and MCS with the WAI (p = 0.0001). Workers with higher education had a better work ability (p = 0.002) and shift-work workers had a worse work ability (p = 0.03). Work ability of majority of women was moderate. Considering mean age of studied women (27.6 years old), this work ability is not satisfactory. Physical and mental components of the HRQoL were the important factors associated with work ability. This work is available in Open Access model and licensed under a CC BY-NC 3.0 PL license.

An empirical comparative study on biological age estimation algorithms with an application of Work Ability Index (WAI).

PubMed

Cho, Il Haeng; Park, Kyung S; Lim, Chang Joo

2010-02-01

In this study, we described the characteristics of five different biological age (BA) estimation algorithms, including (i) multiple linear regression, (ii) principal component analysis, and somewhat unique methods developed by (iii) Hochschild, (iv) Klemera and Doubal, and (v) a variant of Klemera and Doubal's method. The objective of this study is to find the most appropriate method of BA estimation by examining the association between Work Ability Index (WAI) and the differences of each algorithm's estimates from chronological age (CA). The WAI was found to be a measure that reflects an individual's current health status rather than the deterioration caused by a serious dependency with the age. Experiments were conducted on 200 Korean male participants using a BA estimation system developed principally under the concept of non-invasive, simple to operate and human function-based. Using the empirical data, BA estimation as well as various analyses including correlation analysis and discriminant function analysis was performed. As a result, it had been confirmed by the empirical data that Klemera and Doubal's method with uncorrelated variables from principal component analysis produces relatively reliable and acceptable BA estimates. 2009 Elsevier Ireland Ltd. All rights reserved.

Assessing the Global Climate Response to Freshwater Forcing from the Antarctic Ice Sheet Under Future Climate Scenarios

NASA Astrophysics Data System (ADS)

Rogstad, S.; Condron, A.; DeConto, R.; Pollard, D.

2017-12-01

Observational evidence indicates that the West Antarctic Ice Sheet (WAIS) is losing mass at an accelerating rate. Impacts to global climate resulting from changing ocean circulation patterns due to increased freshwater runoff from Antarctica in the future could have significant implications for global heat transport, but to-date this topic has not been investigated using complex numerical models with realistic freshwater forcing. Here, we present results from a high resolution fully coupled ocean-atmosphere model (CESM 1.2) forced with runoff from Antarctica prescribed from a high resolution regional ice sheet-ice shelf model. Results from the regional simulations indicate a potential freshwater contribution from Antarctica of up to 1 m equivalent sea level rise by the end of the century under RCP 8.5 indicating that a substantial input of freshwater into the Southern Ocean is possible. Our high resolution global simulations were performed under IPCC future climate scenarios RCP 4.5 and 8.5. We will present results showing the impact of WAIS collapse on global ocean circulation, sea ice, air temperature, and salinity in order to assess the potential for abrupt climate change triggered by WAIS collapse.

Evidence for heterogeneous (and possibly transient) geothermal flux beneath the Ross-Amundsen ice divide of the West Antarctic ice sheet

NASA Astrophysics Data System (ADS)

Blankenship, D. D.; Danque, H. A.; Quartini, E.; Young, D. A.

2012-12-01

It is well established that the geological framework for the evolution of the marine-based West Antarctic ice sheet (WAIS) is the Cretaceous through Cenozoic rifting of the underlying lithosphere. The southern flank of this rift along the Whitmore Mountains underlies the upper reaches of the Ross Sea catchment of the WAIS and has been identified as a site of active subglacial volcanism. Interestingly, the northern flank of this rift represented by the upward doming of the Marie Byrd Land volcanic province has not yet been associated with active subglacial volcanism. Similarly, it is not known whether the heterogeneity of geothermal flux associated with these existing and potential rift flank volcanic provinces extends across the floor of the rift between the rift flanks. Here we present geophysical evidence for heterogeneous geothermal flux associated with active subglacial volcanism along the northern rift flank adjacent to Marie Byrd Land where it intersects the ice divide for the Ross and Amundsen Sea sectors for the WAIS. We further evaluate the evidence for the continuity of heterogeneous geothermal flux along this ice divide and across the rift floor between the two flanks of the West Antarctic rift system.

Editing Wikipedia content by screen reader: easier interaction with the Accessible Rich Internet Applications suite.

PubMed

Buzzi, Marina; Leporini, Barbara

2009-07-01

This study aims to improve Wikipedia usability for the blind and promote the application of standards relating to Web accessibility and usability. First, accessibility and usability of Wikipedia home, search result and edit pages are analysed using the JAWS screen reader; next, suggestions for improving interaction are proposed and a new Wikipedia editing interface built. Most of the improvements were obtained using the Accessible Rich Internet Applications (WAI-ARIA) suite, developed by the World Wide Web Consortium (W3C) within the framework of the Web Accessibility Initiative (WAI). Last, a scenario of use compares interaction of blind people with the original and the modified interfaces. Our study highlights that although all contents are accessible via screen reader, usability issues exist due to the user's difficulties when interacting with the interface. The scenario of use shows how building an editing interface with the W3C WAI-ARIA suite eliminates many obstacles that can prevent blind users from actively contributing to Wikipedia. The modified Wikipedia editing page is simpler to use via a screen reader than the original one because ARIA ensures a page overview, rapid navigation, and total control of what is happening in the interface.

Cognitive Profile of Intellectually Gifted Adults: Analyzing the Wechsler Adult Intelligence Scale.

PubMed

Lang, Margherita; Matta, Michael; Parolin, Laura; Morrone, Cristina; Pezzuti, Lina

2017-09-01

The Wechsler Adult Intelligence Scale (WAIS) has been used extensively to study intellectual abilities of special groups. Here, we report the results of an intellectually gifted group on the WAIS-IV. Gifted individuals are people who obtained scores equal to or greater than 2 standard deviations above the mean on an intelligence test. Hence, the current study aims first, to examine mean group performance data of gifted individuals on the WAIS-IV; second, to revalidate the pattern of performance identified in this special group in previous studies (i.e., verbal skills higher than all other abilities); third, to compare scatter measures across intellectual domains with a matched comparison group. A total of 130 gifted individuals (79 males) were administered the full battery and their performance was compared with a matched comparison group. Analyses revealed that gifted group displayed higher scores in all intellectual domains. Contrary to expectations, they showed the highest scores in perceptual reasoning tasks. A multivariate approach revealed that this ability was statistically different from all other domains within the gifted group. Moreover, gifted individuals showed higher discrepancies across intellectual domains than average-intelligence people. Findings have important practical implications to detect intellectual giftedness in adulthood.

Augmenting the core battery with supplementary subtests: Wechsler adult intelligence scale--IV measurement invariance across the United States and Canada.

PubMed

Bowden, Stephen C; Saklofske, Donald H; Weiss, Lawrence G

2011-06-01

Examination of measurement invariance provides a powerful method to evaluate the hypothesis that the same set of psychological constructs underlies a set of test scores in different populations. If measurement invariance is observed, then the same psychological meaning can be ascribed to scores in both populations. In this study, the measurement model including core and supplementary subtests of the Wechsler Adult Intelligence Scale-Fourth edition (WAIS-IV) were compared across the U.S. and Canadian standardization samples. Populations were compared on the 15 subtest version of the test in people aged 70 and younger and on the 12 subtest version in people aged 70 or older. Results indicated that a slightly modified version of the four-factor model reported in the WAIS-IV technical manual provided the best fit in both populations and in both age groups. The null hypothesis of measurement invariance across populations was not rejected, and the results provide direct evidence for the generalizability of convergent and discriminant validity studies with the WAIS-IV across populations. Small to medium differences in latent means favoring Canadians highlight the value of local norms.

Therapeutic alliance and obesity management in primary care - a cross-sectional pilot using the Working Alliance Inventory.

PubMed

Sturgiss, E A; Sargent, G M; Haesler, E; Rieger, E; Douglas, K

2016-12-01

Therapeutic alliance is a well-recognized predictor of patient outcomes within psychological therapy. It has not been applied to obesity interventions, and Bordin's theoretical framework shows particular relevance to the management of obesity in primary health care. This cross-sectional study of a weight management programme in general practice aimed to determine if therapeutic alliance was associated with patient outcomes. The Working Alliance Inventory short revised version (WAI-SR) was administered to 23 patients and 11 general practitioners (GPs) at the end of a 6-month weight management programme. Use of the WAI-SR indicated that the strength of therapeutic alliance varied between different patient-GP relationships in this pilot intervention. A robust therapeutic alliance was strongly associated with patient engagement in the weight management programme indicated by number of appointments. It was also associated with some general health and quality of life outcomes. These are promising results that require confirmation with larger studies in primary health care. The measurement of therapeutic alliance using the WAI-SR may predict patient attendance and outcomes in obesity interventions in primary healthcare settings. © 2016 World Obesity Federation.

Inferring Ice Thickness from a Glacier Dynamics Model and Multiple Surface Datasets.

NASA Astrophysics Data System (ADS)

Guan, Y.; Haran, M.; Pollard, D.

2017-12-01

The future behavior of the West Antarctic Ice Sheet (WAIS) may have a major impact on future climate. For instance, ice sheet melt may contribute significantly to global sea level rise. Understanding the current state of WAIS is therefore of great interest. WAIS is drained by fast-flowing glaciers which are major contributors to ice loss. Hence, understanding the stability and dynamics of glaciers is critical for predicting the future of the ice sheet. Glacier dynamics are driven by the interplay between the topography, temperature and basal conditions beneath the ice. A glacier dynamics model describes the interactions between these processes. We develop a hierarchical Bayesian model that integrates multiple ice sheet surface data sets with a glacier dynamics model. Our approach allows us to (1) infer important parameters describing the glacier dynamics, (2) learn about ice sheet thickness, and (3) account for errors in the observations and the model. Because we have relatively dense and accurate ice thickness data from the Thwaites Glacier in West Antarctica, we use these data to validate the proposed approach. The long-term goal of this work is to have a general model that may be used to study multiple glaciers in the Antarctic.

[Occupational stress effects on work ability in chemistry workers].

PubMed

Yang, Huifang; Wang, Mianzhen; Wang, Zhiming; Lan, Yajia

2004-03-01

Investigating the status of work ability and occupational stress in 1030 chemistry workers at levels of chemical materials and explore their relationship and influence factors (481 workers of study group, 549 workers of control group). Work ability and occupational stress were measured with the work ability index (WAI) and occupational stress questionnaire (OSQ). The risk factors of work ability decline were evaluated. WAI and OSQ scores scores are significantly different between study group and control group (P < 0.01), and work ability correlated inversely with occupational stress (P < 0.01). The WAI scores are reducing with a higher of the OSQ. The work ability of chemistry-workers became lower with the increasing of age. Variables that influence work ability included the factors of disorder of musculoskeletal function (OR = 2.884), assessment of the current health (OR = 2.651), the diseases (OR = 2.498), emotion status (OR = 2.407), physical load (OR = 1.254) and lack of exercise (OR = 1.956). The stress levels and stress factors had affected work ability in chemistry-workers, and it was suggested that the findings could be helpful for the measures protecting and promoting of work ability on the health of workers.

Reflections on work as done (WAD) and work as imagined (WAI) in an emergency response organization: A study on firefighters training exercises.

PubMed

Carvalho, Paulo Victor R de; Righi, Angela W; Huber, Gilbert J; Lemos, Caio de F; Jatoba, Alessandro; Gomes, José Orlando

2018-04-01

Emergency response organizations need to be resilient to cope with escalating events resulting from dynamic, unexpected, or complex situations. In Brazil, the Firefighter Corps are military hierarchal organizations with a culture based on fixed structures, well defined norms and procedures. These push against innovations which are necessary to be resilient. This research describes how firefighter captains in the 30-35-year age range managed an emergency response escalation in light of standard operating procedures (SOPs) during a training exercise. The study used ethnographic methods to find and discuss gaps between the instructions and the activities carried out during the exercise, highlighting the differences between work as done (WAD) and work as imagined (WAI), as it was instantiated in the SOP prescriptions. The aim was to produce reflections on WAI and WAD as a way to raise awareness of the need for a cultural change toward resilience in firefighter organizations. This was achieved through firefighter engagement with a comprehensive visualization of the analysis results which afforded easy interaction between the experts, the data, and the researchers. Copyright © 2017 Elsevier Ltd. All rights reserved.

Work ability assessment in a worker population: comparison and determinants of Work Ability Index and Work Ability score.

PubMed

El Fassi, Mehdi; Bocquet, Valery; Majery, Nicole; Lair, Marie Lise; Couffignal, Sophie; Mairiaux, Philippe

2013-04-08

Public authorities in European countries are paying increasing attention to the promotion of work ability throughout working life and the best method to monitor work ability in populations of workers is becoming a significant question. The present study aims to compare the assessment of work ability based on the use of the Work Ability Index (WAI), a 7-item questionnaire, with another one based on the use of WAI's first item, which consists in the worker's self-assessment of his/her current work ability level as opposed to his/her lifetime best, this single question being termed "Work Ability score" (WAS). Using a database created by an occupational health service, the study intends to answer the following questions: could the assessment of work ability be based on a single-item measure and which are the variables significantly associated with self-reported work ability among those systematically recorded by the occupational physician during health examinations? A logistic regression model was used in order to estimate the probability of observing "poor" or "moderate" WAI levels depending on age, gender, body mass index, smoking status, position held, firm size and diseases reported by the worker in a population of workers aged 40 to 65 and examined between January 2006 and June 2010 (n=12389). The convergent validity between WAS and WAI was statistically significant (rs=0.63). In the multivariable model, age (p<0.001), reported diseases (OR=1.13, 95%CI [1.11-1.15]) and holding a position mostly characterized by physical activity (OR=1.67, 95%CI [1.49-1.87]) increased the probability of reporting moderate or poor work ability. A work position characterized by the predominance of mental activity (OR=0.71, 95%CI [0.61-0.84]) had a favourable impact on work ability. These relations were observed regardless of the work ability measurement tool used. The convergent validity and the similarity in results between WAI and WAS observed in a large population of employed workers should thus foster the use of WAS for systematic screening of work ability. Ageing, overweight, decline in health status, holding a mostly physical job and working in a large-sized firm increase the risk of presenting moderate or poor work ability.

Modern foraminifera assemblages in the Amundsen Sea Embayment

NASA Astrophysics Data System (ADS)

Ewa Jernas, Patrycja; Kuhn, Gerhard; Hillenbrand, Claus-Dieter; Lander Rasmussen, Tine; Forwick, Matthias; Mackensen, Andreas; Schröder, Michael; Smith, James; Klages, Johann Philipp

2015-04-01

The West Antarctic Ice Sheet (WAIS) is considered the most unstable part of the Antarctic Ice Sheet. As the WAIS is mostly grounded below sea level, its stability is of great concern. A collapse of large parts of the WAIS would result in a significant global sea-level rise. At present, the WAIS shows dramatic ice loss in its Amundsen Sea sector, especially in Pine Island Bay. Pine Island Glacier (PIG) is characterised by fast flow, major thinning and rapid grounding-line retreat. Its mass los over recent decades is generally attributed to melting caused by the inflow of warm Circumpolar Deep Water (CDW). Future melting of PIG may result in a sea level tipping point, because it could trigger widespread collapse of the WAIS, especially when considering ongoing climate change. Our research project aims to establish proxies (integration of foraminifera, sediment properties and oceanographic data) for modern environmental conditions by analysing seafloor surface sediments along a transect from the glacier proximal settings to the middle-outer shelf in the eastern Amundsen Sea Embayment. These proxies will then be applied on sediment records spanning the Holocene back to the Last Glacial Maximum for reconstructing spatial and temporal variations of CDW upwelling and ice-ocean interactions during the past c. 23,000 years. We will present preliminary results from the analyses of ten short marine sediment cores (multi and box cores) collected during expeditions JR179 (2008) and ANT-XXVI/3 (2010) along a transect from inner Pine Island Bay to the middle-outer shelf part of the Abbot Palaeo-Ice Stream Trough at water depths ranging from 458 m (middle shelf) to 1444 m (inner shelf). The sediment cores are currently investigated for distribution patterns of planktonic and benthic foraminifera and grain-size distribution at 1 cm resolution. Core tops (0-10 cm) were stained with Rose Bengal for living benthic foraminifera investigations. The chronology of the cores will be based on 210Pb and calibrated 14C dates. First results reveal the presence of living benthic foraminifera in surface sediments of all investigated cores suggesting that modern seabed surfaces were recovered. Moreover, a core retrieved from a water depth of 793 m in the Abbot Palaeo-Ice Stream Trough shows particularly high abundances of planktonic foraminifera Neogloboquadrina pachyderma.

Pediatric CT: implementation of ASIR for substantial radiation dose reduction while maintaining pre-ASIR image noise.

PubMed

Brady, Samuel L; Moore, Bria M; Yee, Brian S; Kaufman, Robert A

2014-01-01

To determine a comprehensive method for the implementation of adaptive statistical iterative reconstruction (ASIR) for maximal radiation dose reduction in pediatric computed tomography (CT) without changing the magnitude of noise in the reconstructed image or the contrast-to-noise ratio (CNR) in the patient. The institutional review board waived the need to obtain informed consent for this HIPAA-compliant quality analysis. Chest and abdominopelvic CT images obtained before ASIR implementation (183 patient examinations; mean patient age, 8.8 years ± 6.2 [standard deviation]; range, 1 month to 27 years) were analyzed for image noise and CNR. These measurements were used in conjunction with noise models derived from anthropomorphic phantoms to establish new beam current-modulated CT parameters to implement 40% ASIR at 120 and 100 kVp without changing noise texture or magnitude. Image noise was assessed in images obtained after ASIR implementation (492 patient examinations; mean patient age, 7.6 years ± 5.4; range, 2 months to 28 years) the same way it was assessed in the pre-ASIR analysis. Dose reduction was determined by comparing size-specific dose estimates in the pre- and post-ASIR patient cohorts. Data were analyzed with paired t tests. With 40% ASIR implementation, the average relative dose reduction for chest CT was 39% (2.7/4.4 mGy), with a maximum reduction of 72% (5.3/18.8 mGy). The average relative dose reduction for abdominopelvic CT was 29% (4.8/6.8 mGy), with a maximum reduction of 64% (7.6/20.9 mGy). Beam current modulation was unnecessary for patients weighing 40 kg or less. The difference between 0% and 40% ASIR noise magnitude was less than 1 HU, with statistically nonsignificant increases in patient CNR at 100 kVp of 8% (15.3/14.2; P = .41) for chest CT and 13% (7.8/6.8; P = .40) for abdominopelvic CT. Radiation dose reduction at pediatric CT was achieved when 40% ASIR was implemented as a dose reduction tool only; no net change to the magnitude of noise in the reconstructed image or the patient CNR occurred. © RSNA, 2013.

Rebamipide ameliorates radiation-induced intestinal injury in a mouse model.

PubMed

Shim, Sehwan; Jang, Hyo-Sun; Myung, Hyun-Wook; Myung, Jae Kyung; Kang, Jin-Kyu; Kim, Min-Jung; Lee, Seung Bum; Jang, Won-Suk; Lee, Sun-Joo; Jin, Young-Woo; Lee, Seung-Sook; Park, Sunhoo

2017-08-15

Radiation-induced enteritis is a major side effect in cancer patients undergoing abdominopelvic radiotherapy. Radiation exposure produces an uncontrolled inflammatory cascade and epithelial cell loss leading to impaired epithelial barrier function. The goal of this study was to determine the effect of rebamipide on regeneration of the intestinal epithelia after radiation injury. The abdomens of C57BL/6 mice were exposed to 13Gy of irradiation (IR) and then the mice were treated with rebamipide. Upon IR, intestinal epithelia were destroyed structurally at the microscopic level and bacterial translocation was increased. The intestinal damage reached a maximum level on day 6 post-IR and intestinal regeneration occurred thereafter. We found that rebamipide significantly ameliorated radiation-induced intestinal injury. In mice treated with rebamipide after IR, intestinal barrier function recovered and expression of the tight junction components of the intestinal barrier were upregulated. Rebamipide administration reduced radiation-induced intestinal mucosal injury. The levels of proinflammatory cytokines and matrix metallopeptidase 9 (MMP9) were significantly reduced upon rebamipide administration. Intestinal cell proliferation and β-catenin expression also increased upon rebamipide administration. These data demonstrate that rebamipide reverses impairment of the intestinal barrier by increasing intestinal cell proliferation and attenuating the inflammatory response by inhibiting MMP9 and proinflammatory cytokine expression in a murine model of radiation-induced enteritis. Copyright © 2017 Elsevier Inc. All rights reserved.

A biomaterial-assisted mesenchymal stromal cell therapy alleviates colonic radiation-induced damage.

PubMed

Moussa, Lara; Pattappa, Girish; Doix, Bastien; Benselama, Sarra-Louiza; Demarquay, Christelle; Benderitter, Marc; Sémont, Alexandra; Tamarat, Radia; Guicheux, Jérôme; Weiss, Pierre; Réthoré, Gildas; Mathieu, Noëlle

2017-01-01

Healthy tissues surrounding abdomino-pelvic tumours can be impaired by radiotherapy, leading to chronic gastrointestinal complications with substantial mortality. Adipose-derived Mesenchymal Stromal Cells (Ad-MSCs) represent a promising strategy to reduce intestinal lesions. However, systemic administration of Ad-MSCs results in low cell engraftment within the injured tissue. Biomaterials, able to encapsulate and withstand Ad-MSCs, can overcome these limitations. A silanized hydroxypropylmethyl cellulose (Si-HPMC) hydrogel has been designed and characterized for injectable cell delivery using the operative catheter of a colonoscope. We demonstrated that hydrogel loaded-Ad-MSCs were viable, able to secrete trophic factors and responsive to the inflammatory environment. In a rat model of radiation-induced severe colonic damage, Ad-MSC + Si-HPMC improve colonic epithelial structure and hyperpermeability compared with Ad-MSCs injected intravenously or locally. This therapeutic benefit is associated with greater engraftment of Si-HPMC-embedded Ad-MSCs in the irradiated colonic mucosa. Moreover, macrophage infiltration near the injection site was less pronounced when Ad-MSCs were embedded in the hydrogel. Si-HPMC induces modulation of chemoattractant secretion by Ad-MSCs that could contribute to the decrease in macrophage infiltrate. Si-HPMC is suitable for cell delivery by colonoscopy and induces protection of Ad-MSCs in the tissue potentiating their therapeutic effect and could be proposed to patients suffering from colon diseases. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

WAIS-III FSIQ and GAI in ability-memory discrepancy analysis.

PubMed

Glass, Laura A; Bartels, Jared M; Ryan, Joseph J

2009-01-01

The present investigation compares WAIS-III FSIQ-WMS-III with GAI-WMS-III discrepancies in 135 male inpatients with suspected memory impairment. Full Scale IQ and GAI scores were highly correlated, r= .96, with mean values of 92.10 and 93.59, respectively. Additional analyses with the ability composites compared to each WMS-III index (IMI, GMI, and DMI), the GAI consistently produced larger difference scores than did the FSIQ; however, effect sizes were relatively small (ES= .12). Lastly, case-by-case analyses demonstrated concordance rates of 86% for the FSIQ-IMI and GAI-IMI comparisons, 85% for the FSIQ-GMI and GAI-GMI, and 82% for the FSIQ-DMI and GAI-DMI.

Wechsler Adult Intelligence Scale-Third Edition short form for index and IQ scores in a psychiatric population.

PubMed

Christensen, Bruce K; Girard, Todd A; Bagby, R Michael

2007-06-01

An eight-subtest short form (SF8) of the Wechsler Adult Intelligence Scale, Third Edition (WAIS-III), maintaining equal representation of each index factor, was developed for use with psychiatric populations. Data were collected from a mixed inpatient/outpatient sample (99 men and 101 women) referred for neuropsychological assessment. Psychometric analyses revealed an optimal SF8 comprising Vocabulary, Similarities, Arithmetic, Digit Span, Picture Completion, Matrix Reasoning, Digit Symbol Coding, and Symbol Search, scored by linear scaling. Expanding on previous short forms, the current SF8 maximizes the breadth of information and reduces administration time while maintaining the original WAIS-III factor structure. (c) 2007 APA, all rights reserved

Use of the Wechsler Adult Intelligence Scale Digit Span subtest for malingering detection: a meta-analytic review.

PubMed

Jasinski, Lindsey J; Berry, David T R; Shandera, Anni L; Clark, Jessica A

2011-03-01

Twenty-four studies utilizing the Wechsler Adult Intelligence Scale (WAIS) Digit Span subtest--either the Reliable Digit Span (RDS) or Age-Corrected Scaled Score (DS-ACSS) variant--for malingering detection were meta-analytically reviewed to evaluate their effectiveness in detecting malingered neurocognitive dysfunction. RDS and DS-ACSS effectively discriminated between honest responders and dissimulators, with average weighted effect sizes of 1.34 and 1.08, respectively. No significant differences were found between RDS and DS-ACSS. Similarly, no differences were found between the Digit Span subtest from the WAIS or Wechsler Memory Scale (WMS). Strong specificity and moderate sensitivity were observed, and optimal cutting scores are recommended.

Evidence-based anatomical review areas derived from systematic analysis of cases from a radiological departmental discrepancy meeting.

PubMed

Chin, S C; Weir-McCall, J R; Yeap, P M; White, R D; Budak, M J; Duncan, G; Oliver, T B; Zealley, I A

2017-10-01

To produce short checklists of specific anatomical review sites for different regions of the body based on the frequency of radiological errors reviewed at radiology discrepancy meetings, thereby creating "evidence-based" review areas for radiology reporting. A single centre discrepancy database was retrospectively reviewed from a 5-year period. All errors were classified by type, modality, body system, and specific anatomical location. Errors were assigned to one of four body regions: chest, abdominopelvic, central nervous system (CNS), and musculoskeletal (MSK). Frequencies of errors in anatomical locations were then analysed. There were 561 errors in 477 examinations; 290 (46%) errors occurred in the abdomen/pelvis, 99 (15.7%) in the chest, 117 (18.5%) in the CNS, and 125 (19.9%) in the MSK system. In each body system, the five most common location were chest: lung bases on computed tomography (CT), apices on radiography, pulmonary vasculature, bones, and mediastinum; abdominopelvic: vasculature, colon, kidneys, liver, and pancreas; CNS: intracranial vasculature, peripheral cerebral grey matter, bone, parafalcine, and the frontotemporal lobes surrounding the Sylvian fissure; and MSK: calvarium, sacrum, pelvis, chest, and spine. The five listed locations accounted for >50% of all perceptual errors suggesting an avenue for focused review at the end of reporting. Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.

The effects of training by virtual reality or gym ball on pelvic floor muscle strength in postmenopausal women: a randomized controlled trial.

PubMed

Martinho, Natalia M; Silva, Valéria R; Marques, Joseane; Carvalho, Leonardo C; Iunes, Denise H; Botelho, Simone

2016-03-22

To evaluate the effectiveness of abdominopelvic training by virtual reality compared to pelvic floor muscle training (PFMT) using a gym ball (a previously tested and efficient protocol) on postmenopausal women's pelvic floor muscle (PFM) strength. A randomized controlled trial was conducted with 60 postmenopausal women, randomly allocated into two groups: Abdominopelvic training by virtual reality - APT_VR (n=30) and PFMT using a gym ball - PFMT_GB (n=30). Both types of training were supervised by the same physical therapist, during 10 sessions each, for 30 minutes. The participants' PFM strength was evaluated by digital palpation and vaginal dynamometry, considering three different parameters: maximum strength, average strength and endurance. An intention-to-treat approach was used to analyze the participants according to original groups. No significant between-group differences were observed in most analyzed parameters. The outcome endurance was higher in the APT_VR group (p=0.003; effect size=0.89; mean difference=1.37; 95% CI=0.46 to 2.28). Both protocols have improved the overall PFM strength, suggesting that both are equally beneficial and can be used in clinical practice. Muscle endurance was higher in patients who trained using virtual reality.

The effects of training by virtual reality or gym ball on pelvic floor muscle strength in postmenopausal women: a randomized controlled trial

PubMed Central

Martinho, Natalia M.; Silva, Valéria R.; Marques, Joseane; Carvalho, Leonardo C.; Iunes, Denise H.; Botelho, Simone

2016-01-01

ABSTRACT Objective To evaluate the effectiveness of abdominopelvic training by virtual reality compared to pelvic floor muscle training (PFMT) using a gym ball (a previously tested and efficient protocol) on postmenopausal women’s pelvic floor muscle (PFM) strength. Method A randomized controlled trial was conducted with 60 postmenopausal women, randomly allocated into two groups: Abdominopelvic training by virtual reality – APT_VR (n=30) and PFMT using a gym ball – PFMT_GB (n=30). Both types of training were supervised by the same physical therapist, during 10 sessions each, for 30 minutes. The participants’ PFM strength was evaluated by digital palpation and vaginal dynamometry, considering three different parameters: maximum strength, average strength and endurance. An intention-to-treat approach was used to analyze the participants according to original groups. Results No significant between-group differences were observed in most analyzed parameters. The outcome endurance was higher in the APT_VR group (p=0.003; effect size=0.89; mean difference=1.37; 95% CI=0.46 to 2.28). Conclusion Both protocols have improved the overall PFM strength, suggesting that both are equally beneficial and can be used in clinical practice. Muscle endurance was higher in patients who trained using virtual reality. PMID:27437716

Four- and five-factor models of the WAIS-IV in a clinical sample: Variations in indicator configuration and factor correlational structure.

PubMed

Staffaroni, Adam M; Eng, Megan E; Moses, James A; Zeiner, Harriet Katz; Wickham, Robert E

2018-05-01

A growing body of research supports the validity of 5-factor models for interpreting the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV). The majority of these studies have utilized the WAIS-IV normative or clinical sample, the latter of which differs in its diagnostic composition from the referrals seen at outpatient neuropsychology clinics. To address this concern, 2 related studies were conducted on a sample of 322 American military Veterans who were referred for outpatient neuropsychological assessment. In Study 1, 4 hierarchical models with varying indicator configurations were evaluated: 3 extant 5-factor models from the literature and the traditional 4-factor model. In Study 2, we evaluated 3 variations in correlation structure in the models from Study 1: indirect hierarchical (i.e., higher-order g), bifactor (direct hierarchical), and oblique models. The results from Study 1 suggested that both 4- and 5-factor models showed acceptable fit. The results from Study 2 showed that bifactor and oblique models offer improved fit over the typically specified indirect hierarchical model, and the oblique models outperformed the orthogonal bifactor models. An exploratory analysis found improved fit when bifactor models were specified with oblique rather than orthogonal latent factors. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Active volcanism beneath the West Antarctic ice sheet and implications for ice-sheet stability

USGS Publications Warehouse

Blankenship, D.D.; Bell, R.E.; Hodge, S.M.; Brozena, J.M.; Behrendt, John C.; Finn, C.A.

1993-01-01

IT is widely understood that the collapse of the West Antarctic ice sheet (WAIS) would cause a global sea level rise of 6 m, yet there continues to be considerable debate about the detailed response of this ice sheet to climate change1-3. Because its bed is grounded well below sea level, the stability of the WAIS may depend on geologically controlled conditions at the base which are independent of climate. In particular, heat supplied to the base of the ice sheet could increase basal melting and thereby trigger ice streaming, by providing the water for a lubricating basal layer of till on which ice streams are thought to slide4,5. Ice streams act to protect the reservoir of slowly moving inland ice from exposure to oceanic degradation, thus enhancing ice-sheet stability. Here we present aerogeophysical evidence for active volcanism and associated elevated heat flow beneath the WAIS near the critical region where ice streaming begins. If this heat flow is indeed controlling ice-stream formation, then penetration of ocean waters inland of the thin hot crust of the active portion of the West Antarctic rift system could lead to the disappearance of ice streams, and possibly trigger a collapse of the inland ice reservoir.

Discrepancies between bilinguals' performance on the Spanish and English versions of the WAIS Digit Span task: Cross-cultural implications.

PubMed

López, Enrique; Steiner, Alexander J; Hardy, David J; IsHak, Waguih W; Anderson, W Brantley

2016-01-01

This study explored within-subjects differences in the performance of 40 bilingual participants on the English and Spanish versions of the Wechsler Adult Intelligence Scale (WAIS) Digit Span task. To test the linguistic hypothesis that individuals would perform worse in Spanish because of its syllabic demand, we compared the number of syllables correctly recalled by each participant for every correct trial. Our analysis of the correct number of syllables remembered per trial showed that participants performed significantly better (i.e., recalling more syllables) in Spanish than in English on the total score. Findings suggest the Spanish version of the Digit Span (total score) was significantly more difficult than the English version utilizing traditional scoring methods. Moreover, the Forward Trial, rather than the Backward Trial, was more likely to show group differences between both language versions. Additionally, the Spanish trials of the Digit Span were correlated with language comprehension and verbal episodic memory measures, whereas the English trials of the Digit Span were correlated with confrontational naming and verbal fluency tasks. The results suggest that more research is necessary to further investigate other cognitive factors, rather than just syllabic demand, that might contribute to performance and outcome differences on the WAIS Digit Span in Spanish-English bilinguals.

IS THE PREFRONTAL CORTEX IMPORTANT FOR FLUID INTELLIGENCE? A NEUROPSYCHOLOGICAL STUDY USING MATRIX REASONING

PubMed Central

Tranel, Daniel; Manzel, Kenneth; Anderson, Steven W.

2008-01-01

Patients with prefrontal damage and severe defects in decision making and emotional regulation often have a remarkable absence of intellectual impairment, as measured by conventional IQ tests such as the WAIS/WAIS-R. This enigma might be explained by shortcomings in the tests, which tend to emphasize measures of “crystallized” (e.g., vocabulary, fund of information) more than “fluid” (e.g., novel problem solving) intelligence. The WAIS-III added the Matrix Reasoning subtest to enhance measurement of fluid reasoning. In a set of four studies, we investigated Matrix Reasoning performances in 80 patients with damage to various sectors of the prefrontal cortex, and contrasted these with the performances of 80 demographically matched patients with damage outside the frontal lobes. The results failed to support the hypothesis that prefrontal damage would disproportionately impair fluid intelligence, and every prefrontal subgroup we studied (dorsolateral, ventromedial, dorsolateral + ventromedial) had Matrix Reasoning scores (as well as IQ scores more generally) that were indistinguishable from those of the brain-damaged comparison groups. Our findings do not support a connection between fluid intelligence and the frontal lobes, although a viable alternative interpretation is that the Matrix Reasoning subtest lacks construct validity as a measure of fluid intelligence. PMID:17853146

Determining the Accuracy of Self-Report Versus Informant-Report Using the Conners' Adult ADHD Rating Scale.

PubMed

Alexander, Lisa; Liljequist, Laura

2016-04-01

The present research examined the validity of self-report versus informant-report in relation to a performance-based indicator of adult ADHD. Archival data from 118 participants (52 males, 66 females) were used to compare Conners' Adult ADHD Rating Scale-Self-Report: Long Format (CAARS-S:L) and Conners' Adult ADHD Rating Scale-Observer Report: Long Format (CAARS-O:L) with discrepancy scores calculated between the Wechsler Adult Intelligence Scale-Third Edition (WAIS-III) Verbal Comprehension Index - Working Memory Index (VCI - WMI) and Perceptual-Organizational Index - Processing Speed Index (POI - PSI) scaled scores. Neither the self- nor informant-report formats of the CAARS were better predictors of discrepancies between WAIS-III Index scores. Intercorrelations between the CAARS-S:L and CAARS-O:L revealed generally higher correlations between the same scales of different formats and among scales measuring externally visible symptoms. Furthermore, regression analysis indicated that both the CAARS-S:L and CAARS-O:L clinical scales contributed a significant proportion of variance in WAIS-III VCI - WMI discrepancy scores (14.7% and 16.4%, respectively). Results did not establish greater accuracy of self-report versus informant-report of ADHD symptomatology, rather demonstrate the need for multimodal assessment of ADHD in adults. © The Author(s) 2013.

The paradox of a long grounding during West Antarctic Ice Sheet retreat in Ross Sea.

PubMed

Bart, Philip J; Krogmeier, Benjamin J; Bart, Manon P; Tulaczyk, Slawek

2017-04-28

Marine geological data show that the West Antarctic Ice Sheet (WAIS) advanced to the eastern Ross Sea shelf edge during the Last Glacial Maximum (LGM) and eventually retreated ~1000 km to the current grounding-line position on the inner shelf. During the early deglacial, the WAIS deposited a voluminous stack of overlapping grounding zone wedges (GZWs) on the outer shelf of the Whales Deep Basin. The large sediment volume of the GZW cluster suggests that the grounding-line position of the paleo-Bindschadler Ice Stream was relatively stationary for a significant time interval. We used an upper bound estimate of paleo-sediment flux to investigate the lower bound duration over which the ice stream would have deposited sediment to account for the GZW volume. Our calculations show that the cluster represents more than three millennia of ice-stream sedimentation. This long duration grounding was probably facilitated by rapid GZW growth. The subsequent punctuated large-distance (~200 km) grounding-line retreat may have been a highly non-linear ice sheet response to relatively continuous external forcing such as gradual climate warming or sea-level rise. These findings indicate that reliable predictions of future WAIS retreat may require incorporation of realistic calculations of sediment erosion, transport and deposition.

Early nodule senescence is activated in symbiotic mutants of pea (Pisum sativum L.) forming ineffective nodules blocked at different nodule developmental stages.

PubMed

Serova, Tatiana A; Tsyganova, Anna V; Tsyganov, Viktor E

2018-04-03

Plant symbiotic mutants are useful tool to uncover the molecular-genetic mechanisms of nodule senescence. The pea (Pisum sativum L.) mutants SGEFix - -1 (sym40), SGEFix - -3 (sym26), and SGEFix - -7 (sym27) display an early nodule senescence phenotype, whereas the mutant SGEFix - -2 (sym33) does not show premature degradation of symbiotic structures, but its nodules show an enhanced immune response. The nodules of these mutants were compared with each other and with those of the wild-type SGE line using seven marker genes that are known to be activated during nodule senescence. In wild-type SGE nodules, transcript levels of all of the senescence-associated genes were highest at 6 weeks after inoculation (WAI). The senescence-associated genes showed higher transcript abundance in mutant nodules than in wild-type nodules at 2 WAI and attained maximum levels in the mutant nodules at 4 WAI. Immunolocalization analyses showed that the ethylene precursor 1-aminocyclopropane-1-carboxylate accumulated earlier in the mutant nodules than in wild-type nodules. Together, these results showed that nodule senescence was activated in ineffective nodules blocked at different developmental stages in pea lines that harbor mutations in four symbiotic genes.

Effects of work-related stress on work ability index among refinery workers

PubMed Central

Habibi, Ehsanollah; Dehghan, Habibollah; Safari, Shahram; Mahaki, Behzad; Hassanzadeh, Akbar

2014-01-01

Introduction: Work-related stress is one of the basic problems in industrial also top 10 work-related health problems and it is increasingly implicated in the development a number of problems such as cardiovascular disease, musculoskeletal diseases, early retirement to employees. On the other hand, early retirement to employees from the workplace has increased on the problems of today's industries. Hereof, improving work ability is one of the most effective ways to enhance the ability and preventing disability and early retirement. The aim of This study is determine the relationship between job stress score and work ability index (WAI) at the refinery workers. Materials and Methods: This is a cross-sectional study in which 171 workers from a refinery in isfahan in 2012 who were working in different occupational groups participated. Based on appropriate assignment sampling, 33 office workers, 69 operational workers, and 69 maintenance workers, respectively, were invited to participate in this study. Two questionnaires including work related-stress and WAI were filled in. Finally, the information was analyzed using the SPSS-20 and statistic tests namely, analysis of covariance Kruskal-Wallis test. Pearson correlation coefficient, ANOVA and t-test. Results: Data analysis revealed that 86% and 14% of participants had moderate and severe stress respectively. Average score of stress and standard deviation was 158.7 ± 17.3 that was in extreme stress range. Average score and standard deviation of WAI questionnaire were 37.18 and 3.86 respectively. That placed in a good range. Pearson correlation coefficient showed that WAI score had significant reversed relationship with a score of stress. Conclusion: According to the results, mean stress score among refinery worker was high and one fator that affect work abiity was high stress, hence training on communication skills and safe working environment in order to decreses stress, enhance the work ability of workers. PMID:24741658

Changes in the Thermohaline Flow due to changes in the WAIS and Astronomical Forcing during the MIS31 Superinterglacial

NASA Astrophysics Data System (ADS)

Justino, F. J.; Lindemann, D.; Kucharski, F.; Wilson, A.; Bromwich, D. H.; Stordal, F.

2017-12-01

The Marine Isotope Stage 31 (MIS31, between 1085 ka and 1055 ka) was characterised by higher extra-tropical air temperatures and a substantial recession of polar glaciers compared to today. Paleoreconstructions and model simulations have increased the understanding of the MIS31 interval, but questions remain regarding the role of the Atlantic and Pacific Oceans in modifying the climate associated with the variations in Earth's orbital parameters. Multi-century coupled climate simulations, with the astronomical configuration of the MIS31 and modified West Antarctic Ice Sheet (WAIS) topography, show an increase in the thermohaline flux and northward oceanic heat transport (OHT) in the Pacific Ocean. These oceanic changes are driven by anomalous atmospheric circulation and increased surface salinity in concert with a stronger meridional overturning circulation (MOC). The intensified northward OHT is responsible for up to 85% of the global OHT anomalies and contributes to the overall reduction in sea-ice in the Northern Hemisphere (NH) due to Earth's astronomical configuration. The relative contributions of the Atlantic Ocean to global OHT and MOC anomalies are minor compared to that of the Pacific. However, sea-ice changes are remarkable, highlighted by decreased (increased) cover in Ross (Weddell) Sea but widespread reductions of sea-ice across the NH. These modeling results have enormous implications for paleoreconstructions of the MIS31 climate that mostly assume overall ice free conditions in the vicinity of the Antarctic continent. Since these reconstructions may depict dominant signals in a particular time interval and locale, they cannot be assumed to geographically represent large-scale domains. Therefore, their ability to reproduce long-term environmental conditions should be considered with care. Finally, it is important to emphasize that understanding past interglacial intervals that are characterized by a depleted WAIS can shed light on the potential effects of increasing atmospheric CO2, as the stability of the WAIS will be a key climate factor in decades to come.

[Occupational and non-occupational determinants of work ability].

PubMed

Makowiec-Dabrowska, Teresa; Koszada-Włodarczyk, Wiesława; Bortkiewicz, Alicja; Gadzicka, Elzbieta; Siedlecka, Jadwiga; Jóźwiak, Zbigniew; Pokorski, Janusz

2008-01-01

Measurements of the work ability subjective assessment, using the work ability index (WAI), are widely applied in the examination of workers. The measurement results suggest that the low level of work ability, which is determined by work-burden factors, health condition, and lifestyles of persons under study, can be a predictor of earlier retirement. The aim of the study was to find out whether WAI can be used in Polish conditions and to identify personal traits and/or job characteristics and conditions of its performance that generate the risk of low work ability. The cross-sectional study embraced 669 men and 536 women at the working age, representing different occupations and exposed to various factors. They self-assessed their work ability by completing a questionnaire that allows to determine WAI values. They also characterized their jobs in terms of physical burden, occupational stress, harmful and strenuous factors, work fatigue, chronic fatigue, and lifestyle. Based on the energy expenditure and health condition (number of diseases), the work burden was objectively defined. A model of multivariate logistic regression was used to assess the effect of the analyzed factors on the risk of low or moderate work ability. The level of work ability in the study group was lower than that observed in analogous occupational groups in other European countries. The results of the analysis indicate that job characterizing factors and workers' individual traits exert a stronger effect on the level of WAI components, which reflect a subjective assessment of work abilities, than factors concerning health conditions. Highly stressogenic work and low tolerance of work burden as well as personal traits (age, frequent alcohol consumption among men and non-occupational burdens among women) represented risk factors responsible for low or moderate VAI values. The measurement of work ability index is an indirect assessment of workers' physical state, and it slightly depends on objective work burdens.

Silybin supplementation during HCV therapy with pegylated interferon-α plus ribavirin reduces depression and anxiety and increases work ability.

PubMed

Malaguarnera, Giulia; Bertino, Gaetano; Chisari, Giuseppe; Motta, Massimo; Vecchio, Michele; Vacante, Marco; Caraci, Filippo; Greco, Carmela; Drago, Filippo; Nunnari, Giuseppe; Malaguarnera, Michele

2016-11-15

Hepatitis C virus infection and interferon treatment are often associated with anxiety, depressive symptoms and poor health-related quality of life. To evaluate the Silybin-vitamin E-phospholipids complex effect on work ability and whether health related factors (anxiety and depression) were associated with work ability in subjects with chronic hepatitis C treated with Pegylated-Interferon-α2b (Peg-IFN) and Ribavirin (RBV). Thirty-one patients (Group A) with chronic hepatitis and other 31 subjects in Group B were recruited in a randomized, prospective, placebo controlled, double blind clinical trial. Group A received 1.5 mg/kg per week of Peg-IFN plus RBV and placebo, while Group B received the same dosage of Peg-IFN plus RBV plus association of Silybin 94 mg + vitamin E 30 mg + phospholipids 194 mg in pills for 12 months. All subjects underwent to laboratory exams and questionnaires to evaluate depression (Beck Depression Inventory - BDI), anxiety (State-trait anxiety inventory - STAI) and work ability (Work ability Index - WAI). The comparison between group A and group B showed significant differences after 6 months in ALT (P < 0.001), and viremia (P < 0.05), after 12 months in ALT (P < 0.001), and AST (P < 0.001), at follow up in AST (P < 0.05), and ALT (P < 0.001). Significant difference were observed after 1 month in WAI (p < 0.001) and BDI (P < 0.05), after 6 months in WAI (P < 0.05) and STAI (P < 0.05), after 12 months and at follow up in WAI, STAI and BDI (p < 0.01). The supplementation with Silybin-vitamin E -phospholipids complex increased work ability and reduced depression and anxiety in patients treated with Peg-IFN and RBV. NCT01957319 , First received: September 25, 2013. Last updated: September 30, 2013 (retrospectively registered).

Transcranial direct current stimulation (tDCS) of frontal cortex decreases performance on the WAIS-IV intelligence test.

PubMed

Sellers, Kristin K; Mellin, Juliann M; Lustenberger, Caroline M; Boyle, Michael R; Lee, Won Hee; Peterchev, Angel V; Fröhlich, Flavio

2015-09-01

Transcranial direct current stimulation (tDCS) modulates excitability of motor cortex. However, there is conflicting evidence about the efficacy of this non-invasive brain stimulation modality to modulate performance on cognitive tasks. Previous work has tested the effect of tDCS on specific facets of cognition and executive processing. However, no randomized, double-blind, sham-controlled study has looked at the effects of tDCS on a comprehensive battery of cognitive processes. The objective of this study was to test if tDCS had an effect on performance on a comprehensive assay of cognitive processes, a standardized intelligence quotient (IQ) test. The study consisted of two substudies and followed a double-blind, between-subjects, sham-controlled design. In total, 41 healthy adult participants were included in the final analysis. These participants completed the Wechsler Adult Intelligence Scale, Fourth Edition (WAIS-IV) as a baseline measure. At least one week later, participants in substudy 1 received either bilateral tDCS (anodes over both F4 and F3, cathode over Cz, 2 mA at each anode for 20 min) or active sham tDCS (2 mA for 40 s), and participants in substudy 2 received either right or left tDCS (anode over either F4 or F3, cathode over Cz, 2 mA for 20 min). In both studies, the WAIS-IV was immediately administered following stimulation to assess for performance differences induced by bilateral and unilateral tDCS. Compared to sham stimulation, right, left, and bilateral tDCS reduced improvement between sessions on Full Scale IQ and the Perceptual Reasoning Index. This demonstration that frontal tDCS selectively degraded improvement on specific metrics of the WAIS-IV raises important questions about the often proposed role of tDCS in cognitive enhancement. Copyright © 2015 Elsevier B.V. All rights reserved.

Work ability of aging teachers in Bulgaria.

PubMed

Vangelova, Katya; Dimitrova, Irina; Tzenova, Bistra

2018-06-08

The work ability of aging teachers is of special interest because of high risk of stress. The aim of the study was to follow the work ability of aging teachers and compare it with that of aging non-teacher professionals. The study included 424 teachers of age ≤ 44 years old (N = 140) and ≥ 45 years old (N = 284), with about 10% male teachers in both age groups, matched by sex and age with non-teacher professionals. Work ability was assessed by means of the Work Ability Index (WAI). Chi2 tests and regression analyses were used for studying WAI scales ratings, diagnosed by physician diseases and WAI ratings. Our data shows comparatively high work ability for both age groups of teachers but WAI of aging teachers was significantly lower in comparison to their younger colleagues as well as aging non-teacher professionals. About 80% of aging groups reported diseases diagnosed by physicians. Cardiovascular, musculoskeletal and respiratory diseases were the most frequently reported by aging teachers, while teachers ≤ 44 years old reported respiratory, cardiovascular, neurological and sensory diseases. With aging significantly higher rates of arterial hypertension, diabetes, injury to hearing and mental disorders were reported by teachers as compared to aging non-teacher professionals. The rates of reported repeated infections of respiratory tracts were high in both age groups of teachers, especially in the group of aging teachers. The estimated work ability impairment due to the disease showed the significant effect of aging for teachers as well as the significant difference when comparing aging teachers and non-teacher professionals. Our data shows high work ability for both age groups of teachers but significantly lower for aging teachers accompanied with higher rates of psychosomatic diseases, including hearing impairment and respiratory diseases. Preservation of teacher health could contribute to maintenance of their work ability and retention in the labor market. This work is available in Open Access model and licensed under a CC BY-NC 3.0 PL license.

Effects of work-related stress on work ability index among refinery workers.

PubMed

Habibi, Ehsanollah; Dehghan, Habibollah; Safari, Shahram; Mahaki, Behzad; Hassanzadeh, Akbar

2014-01-01

Work-related stress is one of the basic problems in industrial also top 10 work-related health problems and it is increasingly implicated in the development a number of problems such as cardiovascular disease, musculoskeletal diseases, early retirement to employees. On the other hand, early retirement to employees from the workplace has increased on the problems of today's industries. Hereof, improving work ability is one of the most effective ways to enhance the ability and preventing disability and early retirement. The aim of This study is determine the relationship between job stress score and work ability index (WAI) at the refinery workers. This is a cross-sectional study in which 171 workers from a refinery in isfahan in 2012 who were working in different occupational groups participated. Based on appropriate assignment sampling, 33 office workers, 69 operational workers, and 69 maintenance workers, respectively, were invited to participate in this study. Two questionnaires including work related-stress and WAI were filled in. Finally, the information was analyzed using the SPSS-20 and statistic tests namely, analysis of covariance Kruskal-Wallis test. Pearson correlation coefficient, ANOVA and t-test. Data analysis revealed that 86% and 14% of participants had moderate and severe stress respectively. Average score of stress and standard deviation was 158.7 ± 17.3 that was in extreme stress range. Average score and standard deviation of WAI questionnaire were 37.18 and 3.86 respectively. That placed in a good range. Pearson correlation coefficient showed that WAI score had significant reversed relationship with a score of stress. According to the results, mean stress score among refinery worker was high and one fator that affect work abiity was high stress, hence training on communication skills and safe working environment in order to decreses stress, enhance the work ability of workers.

'Ike Wai Professional Development Model for Students and Post-docs

NASA Astrophysics Data System (ADS)

Bruno, B. C.

2016-12-01

'Ike Wai: Securing Hawaii's Water Future, funded by NSF EPSCoR, is an interdisciplinary research collaboration among geophysicists, geochemists, engineers, microbiologists, computational modelers, data scientists and social scientists. Key questions include: How much water is there? How does it flow? How long will it last? Undergraduate students, graduate students and post-docs are actively involved in the research, and their professional development is a key part of the project. An underlying principle is that students assume responsibility for their own learning and professional development. Based on the model created by the NSF Center for Microbial Oceanography: Research and Education (C-MORE) (Bruno et al, 2008; Guannel et al 2014, Bottjer et al 2014), the 'Ike Wai professional development program includes (1) Leadership. Each student and post-doc creates an Individualized Professional Development plan, which includes leadership training (provided by external facilitators) and assuming leadership roles (such as developing and implementing trainings for their peers). (2) EDventures. Based on the C-MORE model, EDventures combines proposal-writing training with the incentive of seed money. Rather than providing training a priori, the EDventures model encourages students and post-docs to write a proposal based on guidelines provided. Training occurs during a two-stage review stage: proposers respond to panel reviews and resubmit their proposal within a single review cycle. C-MORE EDventures alumni self-report statistically significant confidence gains on all questions posed. Their subsequent proposal success is envious: of the 12 proposals submitted by to NSF, 50% were funded. (Wood Charlson & Bruno, 2015) (3) Layered Mentoring Network. All ´Ike Wai participants serve as both mentor and mentee. Students are matched with a non-research mentor in addition to their advisor to promote a holistic approach to career development. They will also serve as mentors to more junior students. All mentors are trained and mentoring relationships are carefully monitored to allow for sharing of best practices and early detection of issues that could adversely impact retention.

An unusual early Holocene diatom event north of the Getz Ice Shelf (Amundsen Sea): Implications for West Antarctic Ice Sheet development

NASA Astrophysics Data System (ADS)

Esper, O.; Gersonde, R.; Hillenbrand, C.; Kuhn, G.; Smith, J.

2011-12-01

Modern global change affects not only the polar north but also, and to increasing extent, the southern high latitudes, especially the Antarctic regions covered by the West Antarctic Ice Sheet (WAIS). Consequently, knowledge of the mechanisms controlling past WAIS dynamics and WAIS behaviour at the last deglaciation is critical to predict its development in a future warming world. Geological and palaeobiological information from major drainage areas of the WAIS, like the Amundsen Sea Embayment, shed light on the history of the WAIS glaciers. Sediment records obtained from a deep inner shelf basin north of Getz Ice Shelf document a deglacial warming in three phases. Above a glacial diamicton and a sediment package barren of microfossils that document sediment deposition by grounded ice and below an ice shelf or perennial sea ice cover (possibly fast ice), respectively, a sediment section with diatom assemblages dominated by sea ice taxa indicates ice shelf retreat and seasonal ice-free conditions. This conclusion is supported by diatom-based summer temperature reconstructions. The early retreat was followed by a phase, when exceptional diatom ooze was deposited around 12,500 cal. years B.P. [1]. Microscopical inspection of this ooze revealed excellent preservation of diatom frustules of the species Corethron pennatum together with vegetative Chaetoceros, thus an assemblage usually not preserved in the sedimentary record. Sediments succeeding this section contain diatom assemblages indicating rather constant Holocene cold water conditions with seasonal sea ice. The deposition of the diatom ooze can be related to changes in hydrographic conditions including strong advection of nutrients. However, sediment focussing in the partly steep inner shelf basins cannot be excluded as a factor enhancing the thickness of the ooze deposits. It is not only the presence of the diatom ooze but also the exceptional preservation and the species composition of the diatom assemblage, which point to specific scenarios involving e.g. changes in the food web that can be related to warmer surface water temperatures. Such warming of shelf waters may be related with an overshooting Atlantic Meridional Overturning Circulation (AMOC) and strong injection of warmer North Atlantic Deep Water into the Southern Ocean water masses at Termination I as reported by [2]. Such finding may highlight the effects of AMOC changes on Antarctic ice shelf extent and coastal ecosystems. [1] Hillenbrand et al., 2010. J. Quat. Sci. 25 (3), 280-295. [2] Barker et al., 2010. Nature Geosci. 3, 567-571.

Incidence of the WAIS-R Fuld profile in HIV-1 infection.

PubMed

van Gorp, W G; Tulin, S J; Evans, G; Satz, P

1990-10-01

The incidence of a WAIS-R subtest "marker" sensitive to cholinergic dysfunction was assessed in a sample 116 homosexual males infected with HIV (Acquired Immunodeficiency Syndrome [AIDS] N = 40; AIDS Related Complex [ARC], N = 76). The incidence of positive profiles was low in the overall sample (11/116, 9%), and significantly lower than incidence rates reported for known cholinergic deficient groups (Alzheimer's disease; scopolamine). However, significantly more AIDS patients (8/40, 20%) than ARC patients (3/76, 4%) demonstrated positive profiles. These results suggest that, as a group, persons with ARC or AIDS do not show an increased incidence of the Fuld profile associated with cholinergic disruption, and offer continued support for diagnostic specificity of the Fuld formula for Alzheimer's disease.

Utility of proverb interpretation measures with cardiac transplant candidates.

PubMed

Dugbartey, A T

1998-12-01

To assess metaphorical understanding and proverb interpretation in cardiac transplant candidates, the neuropsychological assessment records of 22 adults with end-stage cardiac disease under consideration for transplantation were analyzed. Neuropsychological tests consisted of the Controlled Oral Word Association Test, Halstead Category Test, Rey-Osterrieth Complex Figure Test (Copy), Trial Making Test, and summed scores for the proverb items of the WAIS-R Comprehension subtest. Analysis showed that the group tended to interpret proverbs literally. Proverb scores were significantly associated with scores on the Similarities and Picture Arrangement subtests of the WAIS-R. There was a moderate negative association between number of reported heart attacks and Proverb scores. The need for brief yet robust assessments including measures of inferential thinking and conceptualization in transplant candidates are highlighted.

A First Estimation of County-Based Green Water Availability and Its Implications for Agriculture and Bioenergy Production in the United States

DOE PAGES

Xu, Hui; Wu, May

2018-02-02

Green water is vital for the terrestrial ecosystem, but water resource assessment often focuses on blue water. In this study, we estimated green water availability for major crops (i.e., corn, soybean, and wheat) and all other users(e.g., forest, grassland, and ecosystem services) at the county level in the United States. We estimated green water resources from effective rain(ER) using three different methods: Smith, U.S. Department of Agriculture-Soil Conservation Service (USDA-SCS), and the NHD plus V2 dataset. The analysis illustrates that, if green water meets all crop water demands, the fraction of green water resources available to all other users variesmore » significantly across regions, from the Northern Plains (0.71) to the Southeast (0.98). At the county level, this fraction varies from 0.23 to 1.0. Green water resources estimated using the three different ER methods present diverse spatiotemporal distribution patterns across regions, which could affect green water availability estimates. The water availability index for green water (WAI_R) was measured taking into account crop water demand and green water resources aggregated at the county level. Beyond these parameters, WAI_R also depends on the precipitation pattern, crop type and spatially differentiated regions. In addition, seasonal analysis indicated that WAI_R is sensitive to the temporal boundary of the analysis.« less

Age-related commonalities and differences in the relationship between executive functions and intelligence: Analysis of the NAB executive functions module and WAIS-IV scores.

PubMed

Buczylowska, Dorota; Petermann, Franz

2017-01-01

Data from five subtests of the Executive Functions Module of the German Neuropsychological Assessment Battery (NAB) and all ten core subtests of the German Wechsler Adult Intelligence Scale - Fourth Edition (WAIS-IV) were used to examine the relationship between executive functions and intelligence in a comparison of two age groups: individuals aged 18-59 years and individuals aged 60-88 years. The NAB subtests Categories and Word Generation demonstrated a consistent correlation pattern for both age groups. However, the NAB Judgment subtest correlated more strongly with three WAIS-IV indices, the Full Scale IQ (FSIQ), and the General Ability Index (GAI) in the older adult group than in the younger group. Additionally, in the 60-88 age group, the Executive Functions Index (EFI) was more strongly correlated with the Verbal Comprehension Index (VCI) than with the Perceptual Reasoning Index (PRI). Both age groups demonstrated a strong association of the EFI with the FSIQ and the Working Memory Index (WMI). The results imply the potential diagnostic utility of the Judgment subtest and a significant relationship between executive functioning and crystallized intelligence at older ages. Furthermore, it may be concluded that there is a considerable age-independent overlap between the EFI and general intelligence, as well as between the EFI and working memory.

Association between work ability and fatigue in Brazilian nursing workers.

PubMed

da Silva, Fabio José; Felli, Vanda Elisa Andres; Martinez, Maria Carmen; Mininel, Vivian Aline; Ratier, Ana Paula Pelegrini

2015-01-01

Impaired work ability is associated with work-related illnesses, early retirement and rising pension costs. To investigate the association between work ability and fatigue in nursing workers. Cross-sectional study conducted with 100 nursing workers from two inpatient units at a public teaching hospital in Sao Paulo, Brazil. The data were collected by means of a socio-demographic profile questionnaire, Work Ability Index (WAI) and Chalder Fatigue Scale. The data were analyzed by means of descriptive and analytical statistical methods, tests of association and multiple linear regression. The study population was mainly composed of women (88% ), exhibited a high educational level (76% ), average age 39.4 years old (SD = 9.5) and 15 years of professional experience, on average. The average score on WAI was good (39.4 points, SD = 6.0) but surprisingly, 35% of the participants exhibited moderate to poor work ability. Fatigue was found in 52% of the participants. The score on WAI decreased in association with fatigue (p <  0.001) and longer length of work in the same workplace (p = 0.001), as well as among nursing technicians compared to nurses (p = 0.040). Fatigue, longer length of work in the same workplace and work category nursing technician were associated with decreased work ability, which emphasizes the need for investment in health and quality of work life.

A First Estimation of County-Based Green Water Availability and Its Implications for Agriculture and Bioenergy Production in the United States

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xu, Hui; Wu, May

Green water is vital for the terrestrial ecosystem, but water resource assessment often focuses on blue water. In this study, we estimated green water availability for major crops (i.e., corn, soybean, and wheat) and all other users(e.g., forest, grassland, and ecosystem services) at the county level in the United States. We estimated green water resources from effective rain(ER) using three different methods: Smith, U.S. Department of Agriculture-Soil Conservation Service (USDA-SCS), and the NHD plus V2 dataset. The analysis illustrates that, if green water meets all crop water demands, the fraction of green water resources available to all other users variesmore » significantly across regions, from the Northern Plains (0.71) to the Southeast (0.98). At the county level, this fraction varies from 0.23 to 1.0. Green water resources estimated using the three different ER methods present diverse spatiotemporal distribution patterns across regions, which could affect green water availability estimates. The water availability index for green water (WAI_R) was measured taking into account crop water demand and green water resources aggregated at the county level. Beyond these parameters, WAI_R also depends on the precipitation pattern, crop type and spatially differentiated regions. In addition, seasonal analysis indicated that WAI_R is sensitive to the temporal boundary of the analysis.« less

Late-Holocene climate evolution at the WAIS Divide site, West Antarctica: Bubble number-density estimates

USGS Publications Warehouse

Fegyveresi, John M.; Alley, R.B.; Spencer, M.K.; Fitzpatrick, J.J.; Steig, E.J.; White, J.W.C.; McConnell, J.R.; Taylor, K.C.

2011-01-01

A surface cooling of ???1.7??C occurred over the ???two millennia prior to ???1700 CE at the West Antarctic ice sheet (WAIS) Divide site, based on trends in observed bubble number-density of samples from the WDC06A ice core, and on an independently constructed accumulation-rate history using annual-layer dating corrected for density variations and thinning from ice flow. Density increase and grain growth in polar firn are both controlled by temperature and accumulation rate, and the integrated effects are recorded in the number-density of bubbles as the firn changes to ice. Numberdensity is conserved in bubbly ice following pore close-off, allowing reconstruction of either paleotemperature or paleo-accumulation rate if the other is known. A quantitative late-Holocene paleoclimate reconstruction is presented for West Antarctica using data obtained from the WAIS Divide WDC06A ice core and a steady-state bubble number-density model. The resultant temperature history agrees closely with independent reconstructions based on stable-isotopic ratios of ice. The ???1.7??C cooling trend observed is consistent with a decrease in Antarctic summer duration from changing orbital obliquity, although it remains possible that elevation change at the site contributed part of the signal. Accumulation rate and temperature dropped together, broadly consistent with control by saturation vapor pressure.

Patient perceived participation in decision making on their antipsychotic treatment: Evidence of validity and reliability of the COMRADE scale in a sample of schizophrenia spectrum disorders.

PubMed

Pérez-Revuelta, José; Villagrán-Moreno, José María; Moreno-Sánchez, Luisa; Pascual-Paño, Juan Manuel; González-Saiz, Francisco

2018-03-23

The aim of this paper is to provide evidence of the validity and reliability of the COMRADE scale (Combined Outcome Measure for Risk communication And treatment Decision making Effectiveness) in patients suffering from schizophrenia spectrum disorders. 150 patients recruited at five mental health centers were assessed using a cross-sectional study design. The COMRADE, WAIS-S (therapeutic alliance) and TSQM (satisfaction with medication) scales were used. Exploratory Factor Analysis identified three factors from the COMRADE (F1: "Risk communication"; F2: "Confidence in decision" and F3: "Knowledge of decisional balance") which explain 45.2, 8.5 and 6% of the variance, respectively. Statistically significant correlations were observed between the scores of the COMRADE subscales with the subscales of the WAI-S and the TSQM. The internal consistency observed for each of the factorial scores of the COMRADE were (Cronbach's alpha values) 0.90, 0.89 and 0.74, respectively. The COMRADE scale offers appropriate psychometric properties for its use as a measure of perceived patient involvement in the shared decision making process in antipsychotic treatment. The use of the COMRADE measure in psychiatric clinical practice and in research studies provides an outcome measure of interventions from the shared decision making model. Copyright © 2018 Elsevier B.V. All rights reserved.

Cognitive impairment in neuromyelitis optica spectrum disorders: A comparison of the Wechsler Adult Intelligence Scale-III and the Wechsler Memory Scale Revised with the Rao Brief Repeatable Neuropsychological Battery.

PubMed

Fujimori, Juichi; Nakashima, Ichiro; Baba, Toru; Meguro, Yuko; Ogawa, Ryo; Fujihara, Kazuo

2017-12-01

Approximately 55% of patients with neuromyelitis optica spectrum disorder (NMOSD) show cognitive impairment as evaluated using the Rao Brief Repeatable Neuropsychological Battery (BRBN), but this frequency appears to be higher than the frequency of specific brain lesions in NMOSD. We studied whether cognitive impairment could be observed in NMOSD patients with no or minor non-specific brain lesions. We evaluated cognitive function in 12 NMOSD and 14 MS patients using the Wechsler Adult Intelligence Scale-III (WAIS-III), the Wechsler Memory Scale-Revised (WMS-R), and the BRBN. We judged as cognitively impaired patients whose scores were below the average by 2 standard deviations or greater in 2 or more cognitive domains. Cognitive impairment was observed in 5 MS patients (35.7%) and in the only NMOSD patient (8.3%) with symptomatic brain lesions, but not in the other NMOSD patients who had no or minor non-specific brain lesions. Meanwhile, 5 NMOSD (41.7%) and 4 MS (28.6%) patients who had normal cognition according to the WAIS-III and WMS-R were assessed as cognitively impaired by the BRBN (which is not standardized for age). Cognitive function in NMOSD patients with no or mild non-specific brain lesions was preserved according to the WAIS-III and WMS-R.

Pediatric cT: Implementation of ASIR for Substantial Radiation Dose Reduction While Maintaining Pre-ASIR Image Noise1

PubMed Central

Brady, Samuel L.; Moore, Bria M.; Yee, Brian S.; Kaufman, Robert A.

2015-01-01

Purpose To determine a comprehensive method for the implementation of adaptive statistical iterative reconstruction (ASIR) for maximal radiation dose reduction in pediatric computed tomography (CT) without changing the magnitude of noise in the reconstructed image or the contrast-to-noise ratio (CNR) in the patient. Materials and Methods The institutional review board waived the need to obtain informed consent for this HIPAA-compliant quality analysis. Chest and abdominopelvic CT images obtained before ASIR implementation (183 patient examinations; mean patient age, 8.8 years ± 6.2 [standard deviation]; range, 1 month to 27 years) were analyzed for image noise and CNR. These measurements were used in conjunction with noise models derived from anthropomorphic phantoms to establish new beam current–modulated CT parameters to implement 40% ASIR at 120 and 100 kVp without changing noise texture or magnitude. Image noise was assessed in images obtained after ASIR implementation (492 patient examinations; mean patient age, 7.6 years ± 5.4; range, 2 months to 28 years) the same way it was assessed in the pre-ASIR analysis. Dose reduction was determined by comparing size-specific dose estimates in the pre- and post-ASIR patient cohorts. Data were analyzed with paired t tests. Results With 40% ASIR implementation, the average relative dose reduction for chest CT was 39% (2.7/4.4 mGy), with a maximum reduction of 72% (5.3/18.8 mGy). The average relative dose reduction for abdominopelvic CT was 29% (4.8/6.8 mGy), with a maximum reduction of 64% (7.6/20.9 mGy). Beam current modulation was unnecessary for patients weighing 40 kg or less. The difference between 0% and 40% ASIR noise magnitude was less than 1 HU, with statistically nonsignificant increases in patient CNR at 100 kVp of 8% (15.3/14.2; P = .41) for chest CT and 13% (7.8/6.8; P = .40) for abdominopelvic CT. Conclusion Radiation dose reduction at pediatric CT was achieved when 40% ASIR was implemented as a dose reduction tool only; no net change to the magnitude of noise in the reconstructed image or the patient CNR occurred. PMID:23901128

[Abdominopelvic recurrence of leiomyosarcoma. Echographic aspects apropos of 19 cases].

PubMed

Capelle, J; Leclère, J

1986-01-01

The recurrence rate after initial surgery of pelvis and abdominal leiomyosarcomas is significant. Quick but silent growth of these tumors requires a regular and frequent follow-up in order to improve the prognosis. Ultrasonography is the simplest way for such a follow-up. We present our experience about 23 operated cases of leiomyosarcomas followed by ultrason; 19 of them recurred with 1 to 6 abdominal and/or pelvic masses. The echographic patterns of recurrences are detailed.

Obturator mononeuropathy caused by lipomatosis of the nerve: a case report.

PubMed

Nardone, Raffaele; Venturi, Alessandro; Ladurner, Gunther; Golaszewski, Stefan; Psenner, Konrad; Tezzon, Frediano

2008-08-01

We report a patient who presented with the clinical features of obturator mononeuropathy. Abdomino-pelvic computed tomography revealed a fusiform mass in the right perivesical space; magnetic resonance imaging (MRI) showed characteristic "coaxial-cable-like" appearance in cross-section and "spaghetti-like" appearance in longitudinal section, pathognomonic of lipomatosis of the nerve. Nerve lipomatosis as the cause of obturator neuropathy has not been previously reported. MRI provides definite and graphic proof of the diagnosis.

Attenuation of postoperative adhesions using a modeled manual therapy.

PubMed

Bove, Geoffrey M; Chapelle, Susan L; Hanlon, Katherine E; Diamond, Michael P; Mokler, David J

2017-01-01

Postoperative adhesions are pathological attachments that develop between abdominopelvic structures following surgery. Considered unavoidable and ubiquitous, postoperative adhesions lead to bowel obstructions, infertility, pain, and reoperations. As such, they represent a substantial health care challenge. Despite over a century of research, no preventive treatment exists. We hypothesized that postoperative adhesions develop from a lack of movement of the abdominopelvic organs in the immediate postoperative period while rendered immobile by surgery and opiates, and tested whether manual therapy would prevent their development. In a modified rat cecal abrasion model, rats were allocated to receive treatment with manual therapy or not, and their resulting adhesions were quantified. We also characterized macrophage phenotype. In separate experiments we tested the safety of the treatment on a strictureplasty model, and also the efficacy of the treatment following adhesiolysis. We show that the treatment led to reduced frequency and size of cohesive adhesions, but not other types of adhesions, such as those involving intraperitoneal fatty structures. This effect was associated with a delay in the appearance of trophic macrophages. The treatment did not inhibit healing or induce undesirable complications following strictureplasty. Our results support that that maintained movements of damaged structures in the immediate postoperative period has potential to act as an effective preventive for attenuating cohesive postoperative adhesion development. Our findings lay the groundwork for further research, including mechanical and pharmacologic approaches to maintain movements during healing.

Rhabdomyosarcoma of Cervix: A Case Report.

PubMed

Hosseini, Maryam Sadat; Ashrafganjoei, Tahereh; Sourati, Ainaz; Tabatabeifar, Morteza; Mohamadianamiri, Mahdiss

2016-06-01

Rhabdomyosarcoma has known as a highly malignant soft tissue sarcoma. It has been the most common soft tissue sarcoma in childhood, accounting for about 3 to 4 % of all cases of childhood cancer. Rhabdomyosarcoma was rare in adults, accounting for 3% of all soft-tissue sarcomas. embryonal rhabdomyosarcoma of female genital tract including uterine cervix in an adult was rare. This study has reported a 33-year-old woman presented with abnormal vaginal discharge. Gynecologic examination revealed a cervical mass with grape- like feature protruding into vagina with posterior- superior vaginal wall involvement. Biopsy has performed and pathologic examination was consistent with embryonal botryoid type rhabdomyosarcoma. She has undergone the staging work up measurements including thoracic computed tomography (CT) scan, abdominopelvic magnetic resonance imaging (MRI), bone scan and bone marrow examination. In exception of abdominopelvic MRI, with 2 suspicious pelvic lymph nodes in addition of cervical mass, all others were normal. Radical hysterectomy with lymph node debulking and ovarian preservation has performed. Final results have shown embryonal botryoid type rhabdomyosarcoma of cervix. ovaries, endometrium, parametrium, and follopian tubes were unremarkable. Pelvic lymph nodes pathology and intraabdominal fluid cytology were negative for malignancy. Lymphovascular invasion was identified. She has advised for adjuvant chemotherapy. This case has reminded that embryonal rhabdomyosarcoma could occur in uncommon site and older female. Longer follow up of these cases has required due to lack of survival data for embryonal rhabdomyosarcoma of this site and age group.

[Comparative study of theoretical literature on cold pathogenic disease in Wai tai mi yao fang (Arcane Essentials from the Imperial Library) and Tai ping sheng hui fang (Taiping Holy Prescriptions for Universal Relief)].

PubMed

Zhang, Huirui; Liang, Yongxuan

2014-09-01

In the Wai tai mi yao fang (Arcane Essentials from the Imperial Library) compiled in 752, its portion on cold pathogenic disorders embodies the achievements before the mid Tang Dynasty, whereas that in the Tai ping sheng hui fang (Taiping Holy Prescriptions for Universal Relief), compiled in 992 embodies those before the early Song Dynasty. Comparison on the theory of cold disorders in both books reveal that, during the 2 centuries period from mid Tang to early Song Dynasties, the texts as a carrier for the transmission of such theory in both show no distinct changes, but only with minor revisions and improvements.

Epilepsy & IQ: the clinical utility of the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) indices in the neuropsychological assessment of people with epilepsy.

PubMed

Baxendale, Sallie; McGrath, Katherine; Thompson, Pamela J

2014-01-01

We examined Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) General Ability Index (GAI) and Full Scale Intelligence Quotient (FSIQ) discrepancies in 100 epilepsy patients; 44% had a significant GAI > FSIQ discrepancy. GAI-FSIQ discrepancies were correlated with the number of antiepileptic drugs taken and duration of epilepsy. Individual antiepileptic drugs differentially interfere with the expression of underlying intellectual ability in this group. FSIQ may significantly underestimate levels of general intellectual ability in people with epilepsy. Inaccurate representations of FSIQ due to selective impairments in working memory and reduced processing speed obscure the contextual interpretation of performance on other neuropsychological tests, and subtle localizing and lateralizing signs may be missed as a result.

Constraints on ice volume changes of the WAIS and Ross Ice Shelf since the LGM based on cosmogenic exposure ages in the Darwin-Hatherton glacial system of the Transantarctic Mountains

NASA Astrophysics Data System (ADS)

Fink, David; Storey, Bryan; Hood, David; Joy, Kurt; Shulmeister, James

2010-05-01

Quantitative assessment of the spatial and temporal scale of ice volume change of the West Antarctic ice sheet (WAIS) and Ross Ice Shelf since the last glacial maximum (LGM) ~20 ka is essential to accurately predict ice sheet response to current and future climate change. Although global sea level rose by approximately 120 metres since the LGM, the contribution of polar ice sheets is uncertain and the timing of any such contribution is controversial. Mackintosh et al (2007) suggest that sectors of the EAIS, similar to those studied at Framnes Mountains where the ice sheet slowly calves at coastal margins, have made marginal contributions to global sea-level rise between 13 and 7 ka. In contrast, Stone et al (2003) document continuing WAIS decay during the mid-late Holocene, raising the question of what was the response of the WAIS since LGM and into the Holocene. Terrestrial evidence is restricted to sparse coastal oasis and ice free mountains which archive limits of former ice advances. Mountain ranges flanking the Darwin-Hatherton glaciers exhibit well-defined moraines, weathering signatures, boulder rich plateaus and glacial tills, which preserve the evidence of advance and retreat of the ice sheet during previous glacial cycles. Previous studies suggest a WAIS at the LGM in this location to be at least 1,000 meters thicker than today. As part of the New Zealand Latitudinal Gradient Project along the Transantarctic, we collected samples for cosmogenic exposure dating at a) Lake Wellman area bordering the Hatherton Glacier, (b) Roadend Nunatak at the confluence of the Darwin and Hatherton glaciers and (c) Diamond Hill which is positioned at the intersection of the Ross Ice Shelf and Darwin Glacier outlet. While the technique of exposure dating is very successful in mid-latitude alpine glacier systems, it is more challenging in polar ice-sheet regions due to the prevalence of cold-based ice over-riding events and absence of outwash processes which removes glacially transported debris. Our glacial geomorphic survey from ice sheet contact edge (~850 masl) to mountain peak at 1600 masl together with a suite of 10Be and 26Al exposure ages, documents a pre-LGM ice volume at least 800 meters thicker than current ice levels which was established at least 2 million years ago. However a complex history of exposure and re-exposure of the ice free regions in this area is seen in accordance with advance and retreat of the ice sheets that feeds into the Darwin -Hatherton system. A cluster of mid-altitude boulders, located below a prominent moraine feature mapped previously as demarcating the LGM ice advance limits, have exposure ages ranging from 30 to 40 ka. Exposure ages for boulders just above the ice contact range from 1to 19 ka and allow an estimate of inheritance. Hence, we conclude that LGM ice volume was not as large as previously estimated and actually little different from what is observed today. These results raise rather serious questions about the implications of a reduced WAIS at the LGM, its effect on the development of the Ross Ice Shelf, and how the Antarctic ice sheets respond to global warming. J. O. Stone et al., Science v299, 99 (2003). A. Mackintosh, D. White, D. Fink, D. Gore et al, Geology, v 35; 551-554 (2007).

The Holocene Minimum of the West Antarctic Ice Sheet: Radiocarbon Model Ages for Subglacial Sediments

NASA Astrophysics Data System (ADS)

Tulaczyk, S. M.; Stansell, N.; Scherer, R. P.; Powell, R. D.

2017-12-01

It is commonly assumed that the West Antarctic Ice Sheet (WAIS) is at the present time as small as it has been since at least the last interglacial period about 125,000 years ago. Yet, our recent analyses of subglacial sediments recovered from beneath the ice sheet indicate regionally widespread presence of radiocarbon. This unstable isotope with half life of 5,730 years should decay to nil if the analyzed subglacial sediment samples have been isolated beneath the ice sheet from the atmosphere and the ocean for 125,000 years (over 20 half lives). However, the apparent radiocarbon ages for these samples are in the range of about 20,000-30,000 years BP, based on radiocarbon Fraction Modern (FM) of a few to several percent. The apparent sediment ages cannot be taken at face value because: (1) they overlap with the Last Glacial Maximum (LGM) when WAIS is known to have extended over 1,000 km past the sediment sampling locations, and (2) Antarctic glacigenic sediments commonly contain significant admixture of old, radiocarbon-dead organic matter. The latter biases apparent radiocarbon ages because it violates the assumption that the initial radiocarbon fraction in a sample was equal to FM. To mitigate the problem with apparent ages, we assume that initial radiocarbon fraction in subglacial sediments was equal to that determined by us independently in J-9 sediments from beneath the Ross Ice Shelf (RIS) and calculate radiocarbon 'model ages' between 1,000 and 6,000 years BP. This period of time overlaps with a regional climatic optimum and with late phases of post-LGM glacioisostatic adjustment in the region (e.g., Kingslake et al., this session). We propose that the grounding line of WAIS, at least on the RIS side, retreated in mid/late Holocene more than 300 km beyond its current position and then re-advanced to reach its modern geometry. This implies that the main body of WAIS was significantly smaller than today in mid/late Holocene and that the ice sheet is capable of large fluctuations on timescales much shorter than previously expected.

Post-LGM grounding line and calving front translations of the West Antarctic Ice Sheet in the Whales Deep paleo-ice-stream trough, eastern Ross Sea, Antarctica

NASA Astrophysics Data System (ADS)

McGlannan, A. J.; Bart, P. J.; Chow, J.

2016-12-01

A large-area (2500 km2) multibeam survey of the Whales Deep paleo-ice-stream trough, eastern Ross Sea, Antarctica was acquired during NBP1502B. This sector of the continental shelf is important as it was covered by grounded and floating ice, which drained the central part of an expanded West Antarctic Ice Sheet (WAIS) during the last glacial cycle. The seafloor geomorphology shows a well-defined cluster of four back stepping grounding zone wedges (GZWs) that were deposited in a partly overlapping fashion on the middle continental shelf during WAIS retreat. These observations permit two end-member possibilities for how the WAIS grounding line and calving front vacated the trough. In the first scenario, each GZW represents successive landward shifts of the grounding line and calving front. In the second scenario, each GZW represents a large-scale retreat and re-advance of grounded and floating ice. To determine which of these two end-member scenarios most accurately describes WAIS retreat from this sector of Ross Sea, we evaluated a grid of kasten and piston cores. The core stations were selected on the basis of backstepping GZWs along the trough axis. Our core data analyses included an integration of visual core descriptions, x-ray images, grain size, water content, total organic carbon, shear strengths, and diatom assemblage data. Core data reveal a single transgressive succession from proximal diamict overlain by sub-ice-shelf and/or open-marine sediments. These data strongly support the first scenario, suggesting that an ice shelf remained continuously intact during the time that the grounding line successively moved from the shelf edge to the middle shelf by small-scale landward translations until the end of the fourth grounding event. Sedimentologic and diatom-assemblage data from the inner shelf show that only the last middle shelf grounding event ended with a long-distance retreat of grounded and then floating ice to south of the modern calving front.

Intelligence or years of education: which is better correlated with memory function in normal elderly Japanese subjects?

PubMed

Murayama, Norio; Iseki, Eizo; Tagaya, Hirokuni; Ota, Kazumi; Kasanuki, Koji; Fujishiro, Hiroshige; Arai, Heii; Sato, Kiyoshi

2013-03-01

We compared differences in intelligence and memory function between normal elderly Japanese subjects with more years of education and those with fewer years of education. We also investigated clinical and neuropsychological factors that are strongly correlated with memory function. There were 118 normal elderly subjects who underwent the Mini-Mental State Examination, Wechsler Adult Intelligence Scale, 3rd edition (WAIS-III), and Wechsler Memory Scale Revised. Subjects with at least 13 years of education were categorized as the H group, and those with 12 years of education or less were categorized as the L group. Age and Mini-Mental State Examination scores were not significantly different between the two groups. On the WAIS-III, there were significant differences between the two groups in Verbal IQ and Full Scale IQ. On the Wechsler Memory Scale Revised, there were significant differences between the two groups in Visual Memory, General Memory, and Delayed Recall. Correlation coefficients between memory function and the other factors demonstrated significant but weak correlations between years of education and General Memory (R = 0.22) and between years of education and Delayed Recall (R = 0.20). Strong correlations were found between Verbal IQ and Verbal Memory (R = 0.45), between Verbal IQ and General Memory (R = 0.49), between Full Scale IQ and General Memory (R = 0.50) and between Full Scale IQ and Delayed Recall (R = 0.48). In normal elderly Japanese subjects, years of education weakly correlated with memory function while Verbal IQ, Full Scale IQ and Verbal Comprehension on WAIS-III had stronger correlations with memory function. Verbal IQ and Verbal Comprehension on WAIS-III were found to be insusceptible to the cognitive decline characteristic of Alzheimer's disease or amnestic mild cognitive impairment. Therefore, verbal intelligence, as measured by Verbal IQ and Verbal Comprehension, may be the most useful factor for inferring premorbid memory function in Alzheimer's disease or amnestic mild cognitive impairment patients. © 2013 The Authors. Psychogeriatrics © 2013 Japanese Psychogeriatric Society.

29 CFR 1983.115 - Special circumstances; wai-ver of rules.

Code of Federal Regulations, 2013 CFR

2013-07-01

..., DEPARTMENT OF LABOR (CONTINUED) PROCEDURES FOR THE HANDLING OF RETALIATION COMPLAINTS UNDER SECTION 219 OF THE CONSUMER PRODUCT SAFETY IMPROVEMENT ACT OF 2008 Miscellaneous Provisions § 1983.115 Special...

Gender and age do not influence the ability to work.

PubMed

Padula, Rosimeire Simprini; da Silva Valente, Luciana do Socorro; de Moraes, Mônica Vasconcelos; Chiavegato, Luciana Dias; Cabral, Cristina Maria Nunes

2012-01-01

Work capacity is related to physical, environmental and psychosocial factors and is influenced by individual characteristics and occupations. The aim of this study was to evaluated the relationship between work capacity, gender and age. 360 people employed at an institution of higher education of both genders and similar age were asked to participate in this study. The ability to work was analyzed using Work Ability Index (WAI). Descriptive statistical, Pearson correlations and ANOVA test was applied. Of these, 197 workers who participated in the study completed and returned the questionnaire. The results show there weren't any significant differences between work ability in relation to gender and age, but we observed an increase variability of responses for WAI score in older workers. No significant differences in the perception of the ability of work between men and women..

Is the pattern of intellectual growth and decline across the adult life span different for men and women?

PubMed

Kaufman, A S; Kaufman-Packer, J L; McLean, J E; Reynolds, C R

1991-11-01

Gender comparisons on the WAIS-R were made for 1,480 adults from the standardization sample, ages 20-74 years, to determine whether men and women differ in their age-related patterns of change on tests of fluid and crystallized abilities. Multivariate analyses of covariance and univariate analyses of covariance were conducted, covarying education, to examine the age + gender interactions. These interactions tended to be nonsignificant and trivial for the WAIS-R Verbal and Performance scales and the 11 subtests, which suggests that both men and women maintain their crystallized abilities through old age, but show early, rapid declines in fluid ability. These results were interpreted in terms of the literature on aging and intelligence, gender differences in cognitive abilities, and gender differences in V-P patterns for patients with unilateral brain damage.

Investigation of process and product parameters for physicochemical properties of rice and mung bean (Vigna radiata) flour based extruded snacks.

PubMed

Sharma, Chetan; Singh, Baljit; Hussain, Syed Zameer; Sharma, Savita

2017-05-01

PR 106 and SML 668 cultivars of rice and mung bean respectively, were studied for their potential to serve as a nutritious snack with improved protein quality and quantity. The effect of extrusion conditions, including feed moisture content (14-18%), screw speed (400-550 rpm) and barrel temperature (130-170°C) on the physicochemical properties (bulk density, water absorption index (WAI), water solubility index (WSI) and hardness) was investigated. The replacement of rice flour at 30% level with mung bean flour for making extruded snacks was evaluated. Pasting temperature increased (84-93 °C) while peak viscosity (2768-408 cP), hold viscosity (2018-369 cP), breakdown (750-39 cP), setback (2697-622 cP) and final viscosity (4715-991 cP) decreased with increasing mung bean flour addition. Increasing feed moisture lowered the specific mechanical energy (SME), WAI and WSI of extrudates whereas increased bulk density and hardness. Higher screw speed had linear positive effect on SME of extruder and negative linear effect on WAI. Positive curvilinear quadratic effect of screw speed was also observed on WSI and density. Higher barrel temperature linearly decreased the SME, density and hardness of extrudates. Developed extrusion cooked rice-mung bean snacks with increased protein content and improved protein quality along with higher dietary fibre and minerals have good potential in effectively delivering the nutrition to the population.

The impact of menopause on work ability in women with severe menopausal symptoms.

PubMed

Geukes, Marije; van Aalst, Mariëlle P; Robroek, Suzan J W; Laven, Joop S E; Oosterhof, Henk

2016-08-01

To measure the impact of menopause on work ability in women with severe menopausal symptoms. This cross-sectional study compared the work ability of a sample of otherwise healthy employed Dutch women (n=205) with that of a sample of first-time attendees of a menopause clinic (n=60); both groups were aged 44-60 years. Self-reported questionnaire data assessing work ability (Work Ability Index; WAI) and menopausal symptoms (Greene Climacteric Scale; GCS) were used. Logistic regression analyses were used to examine whether women with severe menopausal symptoms were more likely to have low work ability (defined as a score <37.0 points on the WAI) than were women in the reference group, after adjustment for individual and lifestyle factors. Symptomatic women had significantly higher total GCS scores (mean 26.7 vs 14.2, t=10.8, P<0.001) and significantly lower WAI scores (median 32.0 vs 40.0, U=2380, P<0.001) than the reference group. They were 8.4 times more likely to report low work ability than their healthy counterparts: 76.7% versus 30.2% (OR 8.4, 95% CI 4.1-17.2). Over three-quarters of symptomatic menopausal women report serious problems in dealing with the physical and mental demands of their work (recorded here as low work ability); hence these women might be at risk of prolonged sickness absence from work. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

The relationship between physical activity and work ability - A cross-sectional study of teachers.

PubMed

Grabara, Małgorzata; Nawrocka, Agnieszka; Powerska-Didkowska, Aneta

2018-01-01

To assess relationship between physical activity (PA) and perceived work ability amongst teachers from the Upper Silesia, Poland. The study involved 171 teachers (129 women, 42 men) of primary and secondary schools of the Upper Silesia, Poland. Physical education teachers were excluded from the study. The level of PA was estimated using the International Physical Activity Questionnaire short version, and perceived work ability was estimated using Work Ability Index (WAI). Male teachers had significantly higher levels of vigorous-intensity PA, moderateintensity PA, and total weekly PA than female teachers. The recommendations of the World Health Organization (WHO) met 46% of studied women and 74% of men. Work ability did not differ between male and female teachers. Work ability was related to age, body mass index (BMI), and PA (vigorous-intensity PA, moderate-intensity PA, total weekly PA). The female teachers with excellent or good WAI had significantly higher levels of vigorous-intensity PA, moderate-intensity PA and total weekly PA than female teachers with moderate or poor WAI. The teachers involving in high or moderate intensity PA could improve their work ability. Further studies should focus on relation between physical activity and work ability among teachers of various age and seniority, from both, urban and rural schools. Int J Occup Med Environ Health 2018;31(1):1-9. This work is available in Open Access model and licensed under a CC BY-NC 3.0 PL license.

Personnel's health surveillance at work: effect of age, body mass index, and shift work on mental workload and work ability index.

PubMed

Safari, Shahram; Akbari, Jafar; Kazemi, Meghdad; Mououdi, Mohammad Amin; Mahaki, Behzad

2013-01-01

Two great changes in developed countries are taking place: populations are ageing and becoming increasingly overweight. Combination of these factors with shift work is a risk factor for work ability and mental workload that are dynamic processes which change greatly throughout an individual's work life. The aim of this study was to investigate mental workload and work ability in textile workers and to identify factors which affect work ability and mental workload. This cross-sectional study was carried out among 194 male workers in textile industry. Employees based on their job group and work conditions have been divided into 6 categories. They completed work ability index and mental workload questionnaires during three work shifts. Body mass index (BMI) and demographic details were recorded. All of the participants rated their work ability as moderate with high mental workload. The mean WAI and mental workload in age group were significant. The mean BMI was 25.5 kg/m(2) (standard deviation 4.1) and the mean age was 40.22 years. There was a statistically significant correlation between work ability index and shift work. Unlike the previous study, a decrease point in WAI started in early age that may be due to life-style work and another psychological factor; on the other hand, NASA-TLX revealed high score in six subscales that can be another reason for low WAI.

WAIS-IV subtest covariance structure: conceptual and statistical considerations.

PubMed

Ward, L Charles; Bergman, Maria A; Hebert, Katina R

2012-06-01

D. Wechsler (2008b) reported confirmatory factor analyses (CFAs) with standardization data (ages 16-69 years) for 10 core and 5 supplemental subtests from the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV). Analyses of the 15 subtests supported 4 hypothesized oblique factors (Verbal Comprehension, Working Memory, Perceptual Reasoning, and Processing Speed) but also revealed unexplained covariance between Block Design and Visual Puzzles (Perceptual Reasoning subtests). That covariance was not included in the final models. Instead, a path was added from Working Memory to Figure Weights (Perceptual Reasoning subtest) to improve fit and achieve a desired factor pattern. The present research with the same data (N = 1,800) showed that the path from Working Memory to Figure Weights increases the association between Working Memory and Matrix Reasoning. Specifying both paths improves model fit and largely eliminates unexplained covariance between Block Design and Visual Puzzles but with the undesirable consequence that Figure Weights and Matrix Reasoning are equally determined by Perceptual Reasoning and Working Memory. An alternative 4-factor model was proposed that explained theory-implied covariance between Block Design and Visual Puzzles and between Arithmetic and Figure Weights while maintaining compatibility with WAIS-IV Index structure. The proposed model compared favorably with a 5-factor model based on Cattell-Horn-Carroll theory. The present findings emphasize that covariance model comparisons should involve considerations of conceptual coherence and theoretical adherence in addition to statistical fit. (c) 2012 APA, all rights reserved

Co-extrusion of food grains-banana pulp for nutritious snacks: optimization of process variables.

PubMed

Mridula, D; Sethi, Swati; Tushir, Surya; Bhadwal, Sheetal; Gupta, R K; Nanda, S K

2017-08-01

Present study was undertaken to optimize the process conditions for development of food grains (maize, defatted soy flour, sesame seed)-banana based nutritious expanded snacks using extrusion processing. Experiments were designed using Box-Behnken design with banana pulp (8-24 g), screw speed (300-350 rpm) and feed moisture (14-16% w.b.). Seven responses viz. expansion ratio (ER), bulk density (BD), water absorption index (WAI), protein, minerals, iron and sensory acceptability were considered for optimizing independent parameters. ER, BD, WAI, protein content, total minerals, iron content, and overall acceptability ranged 2.69-3.36, 153.43-238.83 kg/m 3 , 4.56-4.88 g/g, 15.19-15.52%, 2.06-2.27%, 4.39-4.67 mg/100 g (w.b.) and 6.76-7.36, respectively. ER was significantly affected by all three process variables while BD was influenced by banana pulp and screw speed only. Studied process variables did not affected colour quality except 'a' value with banana pulp and screw speed. Banana pulp had positive correlation with water solubility index, total minerals and iron content and negative with WAI, protein and overall acceptability. Based upon multiple response analysis, optimized conditions were 8 g banana pulp, 350 rpm screw speed and 14% feed moisture indicating the protein, calorie, iron content and overall sensory acceptability in sample as 15.46%, 401 kcal/100 g, 4.48 mg/100 g and 7.6 respectively.

Menopausal vasomotor symptoms are associated with poor self-assessed work ability.

PubMed

Gartoulla, Pragya; Bell, Robin J; Worsley, Roisin; Davis, Susan R

2016-05-01

It has been hypothesised that vasomotor symptoms (VMS), the hallmark of menopause, may affect women's workplace performance. The aim of this study was to investigate the association between VMS and self-reported work ability, taking into account socio-demographic characteristics. Study design/Main Outcome measures: A national cross-sectional survey of women, aged 40-65 years, was conducted between October 2013 and March 2014. Participants provided socio-demographic and lifestyle factors and completed the Menopause Specific Quality of Life Questionnaire (MENQOL) and the Work Ability Index (WAI). Of 2020 women who comprised the study sample, 1274 were in paid employment and 1263 completed the WAI. The WAI score was good-excellent for 81.5% of women and poor-moderate for 18.5%. After adjustment for socio-demographic characteristics, having any VMS was associated with greater likelihood of poor-moderate work ability [odds ratio (OR)=2.45, 95% CI 1.69-3.54]. Poorer work ability was significantly and independently associated with being un-partnered, obese or overweight, smoking, being carer and having insecure housing finance, but not with age. Overall, most women functioned well at work. We observed an association suggesting a relationship not only between menopausal VMS and personal wellbeing, but also between VMS and self-assessed work ability. Although 4 in 5 women functioned well at work, recognition of the association with VMS may improve wellbeing and work performance of working women at midlife. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Reliable and fast quantitative analysis of active ingredient in pharmaceutical suspension using Raman spectroscopy.

PubMed

Park, Seok Chan; Kim, Minjung; Noh, Jaegeun; Chung, Hoeil; Woo, Youngah; Lee, Jonghwa; Kemper, Mark S

2007-06-12

The concentration of acetaminophen in a turbid pharmaceutical suspension has been measured successfully using Raman spectroscopy. The spectrometer was equipped with a large spot probe which enabled the coverage of a representative area during sampling. This wide area illumination (WAI) scheme (coverage area 28.3 mm2) for Raman data collection proved to be more reliable for the compositional determination of these pharmaceutical suspensions, especially when the samples were turbid. The reproducibility of measurement using the WAI scheme was compared to that of using a conventional small-spot scheme which employed a much smaller illumination area (about 100 microm spot size). A layer of isobutyric anhydride was placed in front of the sample vials to correct the variation in the Raman intensity due to the fluctuation of laser power. Corrections were accomplished using the isolated carbonyl band of isobutyric anhydride. The acetaminophen concentrations of prediction samples were accurately estimated using a partial least squares (PLS) calibration model. The prediction accuracy was maintained even with changes in laser power. It was noted that the prediction performance was somewhat degraded for turbid suspensions with high acetaminophen contents. When comparing the results of reproducibility obtained with the WAI scheme and those obtained using the conventional scheme, it was concluded that the quantitative determination of the active pharmaceutical ingredient (API) in turbid suspensions is much improved when employing a larger laser coverage area. This is presumably due to the improvement in representative sampling.

Morphology, severity, and distribution of growth anomalies in the coral, Montipora capitata, at Wai`ōpae, Hawai`i

NASA Astrophysics Data System (ADS)

Burns, J. H. R.; Rozet, N. K.; Takabayashi, M.

2011-09-01

This study investigated the morphology, severity, and distribution of growth anomalies (GAs) in the coral, Montipora capitata, from Wai`ōpae tide pools, southeast Hawai`i Island. A macro-image analysis of skeletal microstructure placed GAs into two definable categories; Type A and Type B. Type A GAs had polyp density reduced by 43.05 ± 0.80% (mean ± SE) compared to healthy M. capitata tissue, with many fused and protrusive tuberculae. Type B GAs had no discernable polyps or calices and fused protuberant coenosteum. The prevalence of Type A and Type B GAs among all M. capitata colonies ( n = 1,093) in 8 tide pools at Wai`ōpae was 22.1% (range 2.8-33.7%) and 8.2% (range 0.0-16.9%), respectively. The proportion of colony surface area occupied by GA (relative GA cover) was quantified to assess the severity of this disease among all surveyed colonies. The relative GA cover was significantly greater on colonies larger than 1 m in diameter than smaller colonies and in the central portion of colonies than in the periphery. Furthermore, relative GA cover was negatively related to water motion ( R 2 = 0.748, P < 0.01). Developing field diagnostic criteria of M. capitata GA allowed for a detailed epizootiological assessment that determined several cofactors associated with disease severity. Such epizootiological analysis is applicable to future studies of GAs elsewhere.

Personnel's Health Surveillance at Work: Effect of Age, Body Mass Index, and Shift Work on Mental Workload and Work Ability Index

PubMed Central

Safari, Shahram; Akbari, Jafar; Kazemi, Meghdad; Mououdi, Mohammad Amin; Mahaki, Behzad

2013-01-01

Introduction. Two great changes in developed countries are taking place: populations are ageing and becoming increasingly overweight. Combination of these factors with shift work is a risk factor for work ability and mental workload that are dynamic processes which change greatly throughout an individual's work life. The aim of this study was to investigate mental workload and work ability in textile workers and to identify factors which affect work ability and mental workload. Methods. This cross-sectional study was carried out among 194 male workers in textile industry. Employees based on their job group and work conditions have been divided into 6 categories. They completed work ability index and mental workload questionnaires during three work shifts. Body mass index (BMI) and demographic details were recorded. Results. All of the participants rated their work ability as moderate with high mental workload. The mean WAI and mental workload in age group were significant. The mean BMI was 25.5 kg/m2 (standard deviation 4.1) and the mean age was 40.22 years. There was a statistically significant correlation between work ability index and shift work. Conclusions. Unlike the previous study, a decrease point in WAI started in early age that may be due to life-style work and another psychological factor; on the other hand, NASA-TLX revealed high score in six subscales that can be another reason for low WAI. PMID:23956756

Comparing Commercial WWW Browsers.

ERIC Educational Resources Information Center

Notess, Greg R.

1995-01-01

Four commercial World Wide Web browsers are evaluated for features such as handling of WWW protocols and different URLs: FTP, Telnet, Gopher and WAIS, and e-mail and news; bookmark capabilities; navigation features; file management; and security support. (JKP)

Patient-specific dose calculations for pediatric CT of the chest, abdomen and pelvis

PubMed Central

Fraser, Nicholas D.; Carver, Diana E.; Pickens, David R.; Price, Ronald R.; Hernanz-Schulman, Marta; Stabin, Michael G.

2015-01-01

Background Organ dose is essential for accurate estimates of patient dose from CT. Objective To determine organ doses from a broad range of pediatric patients undergoing diagnostic chest–abdomen–pelvis CT and investigate how these relate to patient size. Materials and methods We used a previously validated Monte Carlo simulation model of a Philips Brilliance 64 multi-detector CT scanner (Philips Healthcare, Best, The Netherlands) to calculate organ doses for 40 pediatric patients (M:F=21:19; range 0.6–17 years). Organ volumes and positions were determined from the images using standard segmentation techniques. Non-linear regression was performed to determine the relationship between volume CT dose index (CTDIvol)-normalized organ doses and abdominopelvic diameter. We then compared results with values obtained from independent studies. Results We found that CTDIvol-normalized organ dose correlated strongly with exponentially decreasing abdominopelvic diameter (R2>0.8 for most organs). A similar relationship was determined for effective dose when normalized by dose-length product (R2=0.95). Our results agreed with previous studies within 12% using similar scan parameters (i.e. bowtie filter size, beam collimation); however results varied up to 25% when compared to studies using different bowtie filters. Conclusion Our study determined that organ doses can be estimated from measurements of patient size, namely body diameter, and CTDIvol prior to CT examination. This information provides an improved method for patient dose estimation. PMID:26142256

Demons-meigs pseudosyndrome mimicking the symptoms of pregnancy: a case report.

PubMed

Nohuz, Erdogan; Alaboud, Maher; El-Drayi, Bilal; Tamburro, Stefano; Kachkach, Said; Varga, Janos

2014-10-01

The Demons-Meigs syndrome should usually be evoked in case of presence of a typical triad: abdominopelvic mass, ascites and hydrothorax. Its diagnosis appears crucial to prevent the realization of unnecessary surgical procedures. A 32-year-old woman presented in April 2012 to the emergency department of our maternity unit (General Hospital, Thiers, France) with an abdominal distension mimicking the symptoms of a pregnancy at term. Physical examination revealed a voluminous painful abdominopelvic mass, extended from the pelvis to the upper abdomen with a large right pleural effusion. Ultrasound and computed tomography showed it was a tumor measuring more than 300 mm in diameter with a right hydrothorax. Serum CA-125 level was 289 U/ml. Cytologic analysis of the pleural effusion didn't show any malignant cells. In this study, Demons-Meigs syndrome was recognized. A laparoscopico-laparotomic management permitted an aspiration of 23 liters of a brownish liquid and an unilateral adnexectomy after pleural paracentesis was performed. Frozen section demonstrated benign mucinous cystadenoma. The final histologic findings objectified intracystic intestinal type ovarian mucinous borderline tumor. After multidisciplinary consultation, the patient was re-operated one month later. The exploration didn't reveal any suspected lesions and appendectomy and omentectomy were performed. The postoperative course was uneventful. Serum CA-125 level was normal at the time of the reoperation and 24 months after the initial surgery. The preoperative recognition of a Demons-Meigs syndrome or a Demons' pseudosyndrome is essential to avoid useless surgical procedures.

Increasing Orgasm and Decreasing Dyspareunia by a Manual Physical Therapy Technique

PubMed Central

Wurn, Lawrence J; Wurn, Belinda F; Roscow, Amanda S; King, C Richard; Scharf, Eugenia S; Shuster, Jonathan J

2004-01-01

Context Female sexual pain and dysfunction Objective To evaluate the effectiveness of a new site-specific, manual soft-tissue therapy in increasing orgasm and reducing dyspareunia (painful intercourse) in women with histories indicating abdominopelvic adhesion formation. Design and Intervention A total of 29 new patients presenting with infertility or abdominopelvic pain-related problems, and also indicating sexual pain or dysfunction, received a series of treatments (mean, 19.5 hours) designed to address biomechanical dysfunction and restricted mobility due to adhesions affecting the reproductive organs and adjacent structures. Outcome Measures Primary outcome measures were post-test vs pretest scores on: (1) the Female Sexual Function Index (FSFI) full scale, orgasm domain, and pain domain; and (2) 3 supplemental 10-point rating scales of sexual pain levels. Secondary outcome measures were post-test vs pretest scores in the other 4 FSFI domains (desire, arousal, lubrication, and satisfaction). The Wilcoxon signed-rank test was used for all statistical analyses. Results For the 23 patients available for follow-up, the paired FSFI post-test vs pretest scores were significant (P ≤ .003) on all measures. Of the 17 patients who completed the 3 sexual pain scales, the paired post-test vs pretest scores were significant (P ≤ .002) Conclusions Many cases of inhibited orgasm, dyspareunia, and other aspects of sexual dysfunction seem to be treatable by a distinctive, noninvasive manual therapy with no risks and few, if any, adverse effects. The therapy should be considered a new adjunct to existing gynecologic and medical treatments. PMID:15775874

75 FR 27623 - Qualification of Drivers; Exemption Applications; Vision

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-17

.... Askin, Paul J. Bannon, Ernie E. Black, Ronnie F. Bowman, Gary O. Brady, Stephen H. Goldcamp, Steven F. Grass, Wai F. King, Dennis E. Krone, Richard J. McKenzie, Jr., Christopher J. Meerten, Craig W. Miller...

A study on the relationships between age, work experience, cognition, and work ability in older employees working in heavy industry.

PubMed

Chung, Jaeyeop; Park, Juhyung; Cho, Milim; Park, Yunhee; Kim, DeokJu; Yang, Dongju; Yang, Yeongae

2015-01-01

[Purpose] The purpose of this study was to examine the correlation of age, work experience, cognition, and work ability in older employees working in heavy industry. [Subjects and Methods] The study was conducted using 100 subjects who were over 55 years old and worked in heavy industry. To obtain data, we first had the subjects complete the MoCA-K test and Work Ability Index (WAI). The data were then analyzed by frequency and correlation using statistical software (SPSS 21.0). [Results] Through this study, we discovered a significant positive correlation between WAI and MoCA-K, age, and work experience. [Conclusion] This study revealed that work ability in older employees increases not with the number of years worked but with the enhancement of cognitive ability. Special management that focuses on cognition is therefore required for senior employees working in the field of heavy industry.

A gender approach to work ability and its relationship to professional and domestic work hours among nursing personnel.

PubMed

Rotenberg, Lúcia; Portela, Luciana Fernandes; Banks, Bahby; Griep, Rosane Harter; Fischer, Frida Marina; Landsbergis, Paul

2008-09-01

The association between working hours and work ability was examined in a cross-sectional study of male (N=156) and female (N=1092) nurses in three public hospitals. Working hours were considered in terms of their professional and domestic hours per week and their combined impact; total work load. Logistic regression analysis showed a significant association between total work load and inadequate work ability index (WAI) for females only. Females reported a higher proportion of inadequate WAI, fewer professional work hours but longer domestic work hours. There were no significant differences in total work load by gender. The combination of professional and domestic work hours in females seemed to best explain their lower work ability. The findings suggest that investigations into female well-being need to consider their total work load. Our male sample may have lacked sufficient power to detect a relationship between working hours and work ability.

Functional and technological potential of dehydrated Phaseolus vulgaris L. flours.

PubMed

Ramírez-Jiménez, A K; Reynoso-Camacho, R; Mendoza-Díaz, S; Loarca-Piña, G

2014-10-15

The effect of cooking followed by dehydration was evaluated on the bioactive composition, antioxidant activity and technological properties of two varieties (Negro 8025 and Bayo Madero) of common beans. Quercetin, rutin, and phenolic acids were the most abundant phenolics found. Cooking processes resulted in decreased values of some phenolic compounds and antioxidant capacity. A subsequent dehydration increased TEAC values, resistant starch content and decreased starch digestibility. Oligosaccharides and dietary fibre were preserved in both treatments. Variety had a strong impact on phytochemical profile, being Negro 8025 that exhibited the highest content of most of the compounds assessed. Water absorption index (WAI) and oil absorption capacity (OAC) were determined in order to measure technological suitability. Dehydration produced flours with stable WAI and low oil pick up. The results suggest that the flours of Negro 8025 beans have a good potential to be considered as functional ingredient for healthy food products. Copyright © 2014 Elsevier Ltd. All rights reserved.

Latent mnemonic strengths are latent: a comment on Mickes, Wixted, and Wais (2007).

PubMed

Rouder, Jeffrey N; Pratte, Michael S; Morey, Richard D

2010-06-01

Mickes, Wixted, and Wais (2007) proposed a simple test of latent strength variability in recognition memory. They asked participants to rate their confidence using either a 20-point or a 99-point strength scale and plotted distributions of the resulting ratings. They found 25% more variability in ratings for studied than for new items, which they interpreted as providing evidence that latent mnemonic strength distributions are 25% more variable for studied than for new items. We show here that this conclusion is critically dependent on assumptions--so much so that these assumptions determine the conclusions. In fact, opposite conclusions, such that study does not affect the variability of latent strength, may be reached by making different but equally plausible assumptions. Because all measurements of mnemonic strength variability are critically dependent on untestable assumptions, all are arbitrary. Hence, there is no principled method for assessing the relative variability of latent mnemonic strength distributions.

Relation between fluid intelligence and frontal lobe functioning in older adults.

PubMed

Isingrini, M; Vazou, F

1997-01-01

This study reports the relations among normal aging, intelligence, and frontal lobe functioning. Intelligence tasks and frontal lobe functioning tasks were administered to 107 adults from two age groups (25 to 46 years and 70 to 99 years). Intelligence measures were assessed with two crystallized tests (WAIS Vocabulary and Information subtests), one fluid intelligence test (Cattell's Matrices), and one mixed, crystallized and fluid test (WAIS Similarities subtest). Frontal functioning was assessed using the Wisconsin Card Sorting Test (WCST) and two tests of verbal fluency. Significant age differences in favor of the young were found on the two intelligence tests with a fluid component and on all measures of frontal lobe functioning. Correlational analyses examining the relationship of intelligence measures to frontal variables indicated that these last measures were significantly correlated with only fluid intelligence tests in the elderly group. The implications for the relations among aging, fluid intelligence, and frontal lobe functioning are discussed.

The Influence of Cognitive Reserve on Recovery from Traumatic Brain Injury.

PubMed

Donders, Jacobus; Stout, Jacob

2018-04-12

we sought to determine the degree to which cognitive reserve, as assessed by the Test of Premorbid Functioning in combination with demographic variables, could act as a buffer against the effect of traumatic brain injury (TBI) on cognitive test performance. retrospective analysis of a cohort of 121 persons with TBI who completed the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) within 1-12 months after injury. regression analyses indicated that cognitive reserve was a statistically significant predictor of all postinjury WAIS-IV factor index scores, after controlling for various premorbid and comorbid confounding variables. Only for Processing Speed did injury severity make an additional statistically significant contribution to the prediction model. cognitive reserve has a protective effect with regard to the impact of TBI on cognitive test performance but this effect is imperfect and does not completely negate the effect of injury severity.

Oral healthcare challenges for older Punjabi-speaking immigrants.

PubMed

MacEntee, Michael I; Wong, Sabrina T; Smith, André; Beattie, B Lynn; Brondani, Mario; Bryant, S Ross; Graf, Peter; Soheilipour, Shimae

2014-06-01

This study explored how older Punjabi-speaking South-Asian immigrants (four focus groups; 33 participants) in Surrey, British Columbia, perceive oral health and related problems. Content analysis revealed two umbrella themes: (a) interpretations of mouth conditions and (b) challenges to oral health. The umbrella themes had four sub-themes: damage caused by heat (wai), disturbances caused by caries, coping with dentures, and quality of life. Three challenges were considered: home remedies, Western dentistry, and difficulties accessing dentists. Participants explained oral diseases in terms of a systemic infection (resha), and preferred to decrease imbalances of wai in the mouth with home remedies from India. We conclude that older Punjabi-speaking immigrants interpret oral health and disease in the context of both Western and Ayurvedic traditions, and that they manage dental problems with a mix of traditional remedies supplemented, if possible, by elective oral health care in India, and by emergency dental care in Canada.

Architecture of fluid intelligence and working memory revealed by lesion mapping.

PubMed

Barbey, Aron K; Colom, Roberto; Paul, Erick J; Grafman, Jordan

2014-03-01

Although cognitive neuroscience has made valuable progress in understanding the role of the prefrontal cortex in human intelligence, the functional networks that support adaptive behavior and novel problem solving remain to be well characterized. Here, we studied 158 human brain lesion patients to investigate the cognitive and neural foundations of key competencies for fluid intelligence and working memory. We administered a battery of neuropsychological tests, including the Wechsler Adult Intelligence Scale (WAIS) and the N-Back task. Latent variable modeling was applied to obtain error-free scores of fluid intelligence and working memory, followed by voxel-based lesion-symptom mapping to elucidate their neural substrates. The observed latent variable modeling and lesion results support an integrative framework for understanding the architecture of fluid intelligence and working memory and make specific recommendations for the interpretation and application of the WAIS and N-Back task to the study of fluid intelligence in health and disease.

The influence of IQ stratification on WAIS-III/WMS-III FSIQ-general memory index discrepancy base-rates in the standardization sample.

PubMed

Hawkins, K A; Tulsky, D S

2001-11-01

Since memory performance expectations may be IQ-based, unidirectional base rate data for IQ-Memory Score discrepancies are provided in the WAIS-III/WMS-III Technical Manual. The utility of these data partially rests on the assumption that discrepancy base rates do not vary across ability levels. FSIQ stratified base rate data generated from the standardization sample, however, demonstrate substantial variability across the IQ spectrum. A superiority of memory score over FSIQ is typical at lower IQ levels, whereas the converse is true at higher IQ levels. These data indicate that the use of IQ-memory score unstratified "simple difference" tables could lead to erroneous conclusions for clients with low or high IQ. IQ stratified standardization base rate data are provided as a complement to the "predicted difference" method detailed in the Technical Manual.

Testing the limits: cautions and concerns regarding the new Wechsler IQ and Memory scales.

PubMed

Loring, David W; Bauer, Russell M

2010-02-23

The Wechsler Adult Intelligence Scale (WAIS) and the Wechsler Memory Scale (WMS) are 2 of the most common psychological tests used in clinical care and research in neurology. Newly revised versions of both instruments (WAIS-IV and WMS-IV) have recently been published and are increasingly being adopted by the neuropsychology community. There have been significant changes in the structure and content of both scales, leading to the potential for inaccurate patient classification if algorithms developed using their predecessors are employed. There are presently insufficient clinical data in neurologic populations to insure their appropriate application to neuropsychological evaluations. We provide a perspective on these important new neuropsychological instruments, comment on the pressures to adopt these tests in the absence of an appropriate evidence base supporting their incremental validity, and describe the potential negative impact on both patient care and continuing research applications.

Combined ice core and climate-model evidence for the collapse of the West Antarctic Ice Sheet during Marine Isotope Stage 5e.

NASA Astrophysics Data System (ADS)

Steig, Eric J.; Huybers, Kathleen; Singh, Hansi A.; Steiger, Nathan J.; Frierson, Dargan M. W.; Popp, Trevor; White, James W. C.

2015-04-01

It has been speculated that collapse of the West Antarctic Ice Sheet explains the very high eustatic sea level rise during the last interglacial period, marine isotope stage (MIS) 5e, but the evidence remains equivocal. Changes in atmospheric circulation resulting from a collapse of the West Antarctic Ice Sheet (WAIS) would have significant regional impacts that should be detectable in ice core records. We conducted simulations using general circulation models (GCMs) at varying levels of complexity: a gray-radiation aquaplanet moist GCM (GRaM), the slab ocean version of GFDL-AM2 (also as an aquaplanet), and the fully-coupled version of NCAR's CESM with realistic topography. In all the experiments, decreased elevation from the removal of the WAIS leads to greater cyclonic circulation over the West Antarctic region. This creates increased advection of relatively warm marine air from the Amundsen-Bellingshausen Seas towards the South Pole, and increased cold-air advection from the East Antarctic plateau towards the Ross Sea and coastal Marie Byrd Land. The result is anomalous warming in some areas of the East Antarctic interior, and significant cooling in Marie Byrd Land. Comparison of ice core records shows good agreement with the model predictions. In particular, isotope-paleotemperature records from ice cores in East Antarctica warmed more between the previous glacial period (MIS 6) and MIS 5e than coastal Marie Byrd Land. These results add substantial support to other evidence for WAIS collapse during the last interglacial period.

Invalid before impaired: an emerging paradox of embedded validity indicators.

PubMed

Erdodi, Laszlo A; Lichtenstein, Jonathan D

Embedded validity indicators (EVIs) are cost-effective psychometric tools to identify non-credible response sets during neuropsychological testing. As research on EVIs expands, assessors are faced with an emerging contradiction: the range of credible impairment disappears between the 'normal' and 'invalid' range of performance. We labeled this phenomenon as the invalid-before-impaired paradox. This study was designed to explore the origin of this psychometric anomaly, subject it to empirical investigation, and generate potential solutions. Archival data were analyzed from a mixed clinical sample of 312 (M Age  = 45.2; M Education  = 13.6) patients medically referred for neuropsychological assessment. The distribution of scores on eight subtests of the third and fourth editions of Wechsler Adult Intelligence Scale (WAIS) were examined in relation to the standard normal curve and two performance validity tests (PVTs). Although WAIS subtests varied in their sensitivity to non-credible responding, they were all significant predictors of performance validity. While subtests previously identified as EVIs (Digit Span, Coding, and Symbol Search) were comparably effective at differentiating credible and non-credible response sets, their classification accuracy was driven by their base rate of low scores, requiring different cutoffs to achieve comparable specificity. Invalid performance had a global effect on WAIS scores. Genuine impairment and non-credible performance can co-exist, are often intertwined, and may be psychometrically indistinguishable. A compromise between the alpha and beta bias on PVTs based on a balanced, objective evaluation of the evidence that requires concessions from both sides is needed to maintain/restore the credibility of performance validity assessment.

Predicting absenteeism: screening for work ability or burnout.

PubMed

Schouteten, R

2017-01-01

In determining the predictors of occupational health problems, two factors can be distinguished: personal (work ability) factors and work-related factors (burnout, job characteristics). However, these risk factors are hardly ever combined and it is not clear whether burnout or work ability best predicts absenteeism. To relate measures of work ability, burnout and job characteristics to absenteeism as the indicators of occupational health problems. Survey data on work ability, burnout and job characteristics from a Dutch university were related to the absenteeism data from the university's occupational health and safety database in the year following the survey study. The survey contained the Work Ability Index (WAI), Utrecht Burnout Scale (UBOS) and seven job characteristics from the Questionnaire on Experience and Evaluation of Work (QEEW). There were 242 employees in the study group. Logistic regression analyses revealed that job characteristics did not predict absenteeism. Exceptional absenteeism was most consistently predicted by the WAI dimensions 'employees' own prognosis of work ability in two years from now' and 'mental resources/vitality' and the burnout dimension 'emotional exhaustion'. Other significant predictors of exceptional absenteeism frequency included estimated work impairment due to diseases (WAI) and feelings of depersonalization or emotional distance from the work (burnout). Absenteeism among university personnel was best predicted by a combination of work ability and burnout. As a result, measures to prevent absenteeism and health problems may best be aimed at improving an individual's work ability and/or preventing the occurrence of burnout. © The Author 2016. Published by Oxford University Press on behalf of the Society of Occupational Medicine. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Occupational stress is associated with impaired work ability and reduced quality of life in patients with chronic kidney failure.

PubMed

Neri, Luca; Rocca Rey, Luisa A; Gallieni, Maurizio; Brancaccio, Diego; Cozzolino, Mario; Colombi, Antonio; Burroughs, Thomas E

2009-05-01

About 300,000 patients in the United States with Chronic Kidney Failure (CKF) are of working age, but up to 70% lose their job within the first year of renal replacement therapy .No study has examined how work ability and perceived health are influenced by the subjects' adjustment to their job. We assessed the association of occupational stress (Effort-Reward Imbalance, ERI),work ability (WAI) and health-related quality of life (QoL) in hemodialysis. 40 employed hemodialysis patients completed a self-administered questionnaire. Associations between ERI, short Form 12 (sF-12), short Form - 6 Dimensions (sF-6D), Kidney Disease QOL- 36 (KDQOL-36) and WAI were tested with partial Spearman's correlation adjusted for age, income, and comorbidity burden. Study subjects were mainly low-income (82%), african-american (73%), men (75%); 16 were manual laborers and 9 worked in the industrial sector. Study subjects reported low levels of Occupational Stress: ERI scores indicated an imbalance between Job Efforts and Rewards in only 3 subjects. Nevertheless, ERI scores were inversely and strongly associated with WAI (rho=-0.41, p<0.012) and all QoL scales even after adjustment for known confounders. Our study suggests that psychosocial workplace factors may play a substantial role in modulating patients' health perception and ability to continue working. The causal relationship between Occupational stress, perceived health, and work ability should be further investigated. Occupational Health professionals and nephrologists should closely collaborate to meet the needs of occupationally active hemodialysis patients.

Assessment of a model for achieving competency in administration and scoring of the WAIS-IV in post-graduate psychology students.

PubMed

Roberts, Rachel M; Davis, Melissa C

2015-01-01

There is a need for an evidence-based approach to training professional psychologists in the administration and scoring of standardized tests such as the Wechsler Adult Intelligence Scale (WAIS) due to substantial evidence that these tasks are associated with numerous errors that have the potential to significantly impact clients' lives. Twenty three post-graduate psychology students underwent training in using the WAIS-IV according to a best-practice teaching model that involved didactic teaching, independent study of the test manual, and in-class practice with teacher supervision and feedback. Video recordings and test protocols from a role-played test administration were analyzed for errors according to a comprehensive checklist with self, peer, and faculty member reviews. 91.3% of students were rated as having demonstrated competency in administration and scoring. All students were found to make errors, with substantially more errors being detected by the faculty member than by self or peers. Across all subtests, the most frequent errors related to failure to deliver standardized instructions verbatim from the manual. The failure of peer and self-reviews to detect the majority of the errors suggests that novice feedback (self or peers) may be ineffective to eliminate errors and the use of more senior peers may be preferable. It is suggested that involving senior trainees, recent graduates and/or experienced practitioners in the training of post-graduate students may have benefits for both parties, promoting a peer-learning and continuous professional development approach to the development and maintenance of skills in psychological assessment.

75 FR 38603 - Qualification of Drivers; Exemption Renewals; Vision

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-02

... James C. Askin, Paul J. Bannon, Ernie E. Black, Ronnie F. Bowman, Gary O. Brady, Stephen H. Goldcamp, Steven F. Grass, Wai F. King, Dennis E. Krone, Richard J. McKenzie, Jr., Christopher J. Meerten, Craig W...

What can Subglacial Sediment Tell us About the Underlying Geology and the Dynamic of the West-Antarctic Ice Sheet?

NASA Astrophysics Data System (ADS)

Vogel, S. W.; Tulaczyk, S. M.; Carter, S.; Grunow, A.

2003-12-01

The West-Antarctic Ice Sheet (WAIS) is the second largest ice sheet in the world. Its dynamic is extensively studied due to the proposed threat of rapid disintegration and associated sea level rise (Mercer, 1971). Most of its ice drains through a few fast flowing (>100 m/yr) ice streams and outlet glaciers. Subglacial conditions in particular the distribution of basal water and the availability of subglacial sediment plays an important role for their location and extent. Subglacial geology in particular the distribution of sedimentary basin fill, providing material for a lubricating subglacial till layer, may pose a limit on the inland extent of the fast flowing ice stream. Subglacial volcanism and associated elevated geothermal heat fluxes may provide crucial subglacial melt water for ice stream lubrication. We have studied sediment from the base of the WAIS to elucidate questions about the existence of subglacial volcanism and to determine the provenance of the subglacial sediment. Within this study we measured clay mineralogy, sand petrography, magnetic and geochemical properties of subglacial and englacial sediment from different locations in the Ross Sea-catchment area of the WAIS. Our samples come from Whillans-, Kamb- and Bindschadler Ice Stream as well as from Siple Dome, Crary Ice Rise and Byrd Station. Most of our sediment samples represent samples of subglacial till, which in earlier studies have been characterized as reworked marine sediment of Cenozoic age. The englacial sediment samples come from basal ice. Our study so far has found no positive evidence for the existence of subglacial volcanism beneath the WAIS. The mineralogy as well as the REE-pattern of our samples correspond better with a crustal source for the sediment than Cenozoic basalts. The isotopic composition of our samples (Nd/Sm, Rb/Sr) show differences between individual ice streams locations as well as differences between different grain size fractions. TDM-ages range from ~900 Ma to 1800 Ma; ENd between -4 to -12 and 87Sr/86Sr ~0.715 to ~0.735. Our preliminary geochemical results so far point to rocks from outcrops in the upstream areas of the individual ice streams as provenance for their sediment (Horlick Mountains and Whitmore Mountains) with a possibly small East-Antarctic component.

Links between global and local shape perception, coloured backgrounds, colour discrimination, and non-verbal IQ.

PubMed

Dore, Patricia; Dumani, Ardian; Wyatt, Geddes; Shepherd, Alex J

2018-03-16

This study explored associations between local and global shape perception on coloured backgrounds, colour discrimination, and non-verbal IQ (NVIQ). Five background colours were chosen for the local and global shape tasks that were tailored for the cone-opponent pathways early in the visual system (cardinal colour directions: L-M, loosely, reddish-greenish; and S-(L + M), or tritan colours, loosely, blueish-yellowish; where L, M and S refer to the long, middle and short wavelength sensitive cones). Participants also completed the Farnsworth-Munsell 100-hue test (FM100) to determine whether performance on the local and global shape tasks correlated with colour discrimination overall, or with performance on the L-M and tritan subsets of the FM100 test. Overall performance on the local and global shape tasks did correlate with scores on the FM100 tests, despite the colour of the background being irrelevant to the shape tasks. There were also significantly larger associations between scores for the L-M subset of the FM100 test, compared to the tritan subset, and accuracy on some of the shape tasks on the reddish, greenish and neutral backgrounds. Participants also completed the non-verbal components of the WAIS and the SPM+ version of Raven's progressive matrices, to determine whether performance on the FM100 test, and on the local and global shape tasks, correlated with NVIQ. FM100 scores correlated significantly with both WAIS and SPM+ scores. These results extend previous work that has indicated FM100 performance is not purely a measure of colour discrimination, but also involves aspects of each participant's NVIQ, such as the ability to attend to local and global aspects of the test, part-whole relationships, perceptual organisation and good visuomotor skills. Overall performance on the local and global shape tasks correlated only with the WAIS scores, not the SPM+. These results indicate that those aspects of NVIQ that engage spatial comprehension of local-global relationships and manual manipulation (WAIS), rather than more abstract reasoning (SPM+), are related to performance on the local and global shape tasks. Links are presented between various measures of NVIQ and performance on visual tasks, but they are currently seldom addressed in studies of either shape or colour perception. Further studies to explore these issues are recommended. Copyright © 2018 Elsevier Ltd. All rights reserved.

Femoral metastases from ovarian serous/endometroid adenocarcinoma

PubMed Central

Beresford–Cleary, NJA; Mehdi, SA; Magowan, B

2012-01-01

Bony metastases from ovarian cancer are rare, tend to affect the axial skeleton and are associated with abdomino-pelvic disease. The median time interval between diagnosis of ovarian carcinoma and presentation of bony metastases is 44 months (1). We describe a rare case of high grade left ovarian serous / endometrioid adenocarcinoma presenting with a pathological right femoral fracture 4 weeks following diagnosis and optimal debulking of the ovarian tumour. Orthopaedic surgeons must be vigilant when planning treatment of fractures presenting in patients with a history of ovarian cancer. PMID:24960734

Relationships Between Intellectual Factors And Coping In Physical Rehabilitation

ERIC Educational Resources Information Center

Fogel, Max L.; Rosillo, Ronald H.

1973-01-01

Weschler Adult Intelligence Scale (WAIS) prorated IQ and subtest scores were related to improvement in physical rehabilitation. Independent psychiatric ratings evaluated physical improvement in patients from admission to discharge. In physical rehabilitation intelligence apparently may interact differentially with idiosyncratic attributes…

Applying Hypertext Structures to Software Documentation.

ERIC Educational Resources Information Center

French, James C.; And Others

1997-01-01

Describes a prototype system for software documentation management called SLEUTH (Software Literacy Enhancing Usefulness to Humans) being developed at the University of Virginia. Highlights include information retrieval techniques, hypertext links that are installed automatically, a WAIS (Wide Area Information Server) search engine, user…

Telnet Cornucopia: Interactive Access to Information Resource Collections.

ERIC Educational Resources Information Center

Harris, Judi

1992-01-01

Describes various resources accessed through Telnet software that are available through the Internet for use in elementary and secondary education. Highlights include the National Public Telecomputing Network's Cleveland Freenet; Washington University's SERVICES gateway; and Wide Area Information Server (WAIS) programs. (LRW)

Neogene ice sheet, paleoclimatic and geological history of the McMurdo Sound region, Victoria Land Basin, Antarctica: overview of ANDRILL's first two drilling projects

NASA Astrophysics Data System (ADS)

Powell, R.; Naish, T.; Harwood, D.; Florindo, F.; Levy, R.; Teams, M. S.

2008-12-01

The ANtarctic geological DRILLing Program (ANDRILL), an international collaboration within IPY, has recovered 2 cores: from under the Ross Ice Shelf (McMurdo Ice Shelf Project (MIS) - AND-1B), and from the land-fast sea-ice of McMurdo Sound (Southern McMurdo Sound Project (SMS) - AND-2A). Drill cores reached respective total depths of 1285mbsf in c. 850m of water (MIS) and 1138.54mbsf in c. 380m of water (SMS). Repetitive facies successions in AND-1B core imply at least 60 fluctuations, of probable Milankovitch- duration, between subglacial, ice proximal and ice distal open marine environments. These are grouped into 3 types of facies cycles corresponding to glacial-interglacial variability during climatically distinct periods of Late Neogene: (1) cold-polar climate and ice (late Miocene and Pleistocene); (2) relatively warmer climate, polythermal ice and interglacials dominated by pelagic diatomite (Pliocene); (3) warmer climate, polythermal ice with interglacials dominated by hemipelagites (early late Miocene). A c. 80m-thick interval of diatomite of mid to late Pliocene age shows no apparent glacial cyclicity and represents an extended period of ice-free conditions indicating reduced or absent WAIS. Late Pliocene glacial-interglacial cycles characterized by abrupt alternations between subglacial/ice-proximal facies and open marine diatomite units imply significant WAIS dynamism, and contribution to global ice volume changes coeval with the initiation of Northern Hemisphere glaciations. A c. 4m-thick interval of diatomaceous mudstone in the mid-Pleistocene also represents warm-interglacial ice-free conditions. Intriguingly, glacial deposits interrupted by periodic, small- scale grounding-line retreats dominate the last 1m.y. Inter-hemispheric ice sheet coupling was probably controlled by Northern Hemispheric insolation and consequent glacial eustasy to account for much of the orbital-scale WAIS variability since 2.5Ma. A further expansion of WAIS occurred across the Mid-Pleistocene Climate Transition to establish the present WAIS mode. The AND-2A drillcore recovered several distinct intervals separated by disconformities: (1) a lower Miocene interval (1138.54-c. 800mbsf); (2) a 600m-thick early and middle Miocene interval (800-223mbsf), including an expanded section through two Miocene climatic optima, is truncated by a disconformity that spans c. 7m.y.; and (3) an upper Miocene-Recent interval (223-0mbsf) that is thinner but correlative to parts of the AND-1B drillcore. Shallow marine deposits dominate the lower AND-2A section until c.1.5Ma when the basin deepened rapidly from volcanic loading by Mt Erebus. Lower and middle Miocene strata record repeating lithological changes reflecting variation in sea level, glacial proximity, and climate fluctuations on the shallow marine coast of the Transantarctic Mountains. Sediments deposited close to or beneath grounded glaciers (likely flowing from East Antarctica) alternate with fine-grained marine sediments, providing clear evidence for cycles of ice advance then substantial retreat during climate transitions to warmer conditions. Fossils suggest non-polar climate conditions similar to southern New Zealand today, influenced by high sediment discharge from river run-off, and high coastal turbidity.

Utility and prevalence of imaging for underlying cancer in unprovoked pulmonary embolism.

PubMed

Homewood, R; Medford, A R

2015-01-01

Current guidelines state that patients over 40 years of age with a first unprovoked pulmonary embolism should be offered limited screening for possible cancer and considered for intensive screening (abdomino-pelvic computed tomography and mammography), despite no evidence for the latter. The aim of this study was to evaluate the clinical utility and cost of intensive screening in routine clinical practice. Methods All patients diagnosed with a first unprovoked pulmonary embolism between January 2014 and June 2014 in a single large UK teaching hospital were included. The information management department searched for patients with an International Classification of Diseases 10 discharge diagnosis of pulmonary embolism and limited to 'acute pulmonary embolism with/without cor pulmonale'. Only patients with unprovoked pulmonary embolism were included. Patients with chronic medical conditions predisposing to pulmonary embolism were excluded. NHS costs were obtained from the Trust Finance Department. These costs were used to generate the costs of limited versus intensive screening, and then scaled up using adult population census information and assuming the same incidence of idiopathic pulmonary embolism to estimate the annual NHS cost of intensive screening. Results Ninety-two patients were diagnosed with pulmonary embolism, and 25 met the inclusion criteria. Clinical examination was often incomplete (84%). Limited screening was often missed (urinalysis 100%, serum calcium 64%). Intensive screening was performed in the majority of cases (68%, all abdomino-pelvic computed tomography with no cancer detected) with an £88 excess cost per patient. Conclusion Intensive screening in first unprovoked pulmonary embolism has a low yield, is costly and should not replace thorough clinical examination and basic screening.

Biliary and pancreatic ductal dilation in patients on methadone maintenance therapy.

PubMed

Bates, David D B; Tamayo-Murillo, Dorathy; Kussman, Steven; Luce, Adam; LeBedis, Christina A; Soto, Jorge A; Anderson, Stephan W

2017-03-01

To determine whether the diameter of intrahepatic and extrahepatic bile ducts and pancreatic ducts in patients on methadone maintenance therapy is increased when compared with control subjects. Between January 1, 2000 and March 15, 2013, a total of 97 patients (mean age 49.9, range 22-79, 65 male, 32 female) were identified who were receiving chronic methadone maintenance therapy (MMT) when they underwent imaging with abdominal MRI or a contrast-enhanced abdominopelvic CT. A group of 97 consecutive non-MMT control patients (mean age 51.4, range 21-86, 45 male, 52 female) who underwent imaging with abdominal MRI or contrast-enhanced abdominopelvic CT were identified. Patients with known pancreaticobiliary pathology that may confound biliary ductal measurements were excluded. Blinded interpretation was performed, documenting the diameters of the intrahepatic and extrahepatic bile ducts and pancreatic ducts. Descriptive statistics were performed. Patients on MMT demonstrated increased bile duct diameter, with an average increase in duct diameter of 2.39 mm for the common bile duct (p < 0.001; 95% CI 1.88-2.90 mm), 1.43 mm for the intrahepatic bile ducts (p < 0.001; 95% CI 1.12-1.74 mm), and 0.90 mm for the pancreatic duct (p < 0.001; 95% CI 0.64-1.16 mm). No statistically significant correlation was found between ductal diameters and the daily dose of methadone. Patients on methadone maintenance therapy demonstrate significantly increased intra- and extrahepatic bile duct and pancreatic duct diameter when compared with controls. There was no correlation between the dose of methadone and ductal diameter.

Serum total prostate-specific antigen values in men with symptomatic prostate enlargement in Nigeria: role in clinical decision-making.

PubMed

Nnabugwu, Ikenna I; Ugwumba, Fred O; Enivwenae, Oghenekaro A; Udeh, Emeka I; Otene, Chris O; Nnabugwu, Chinwe A

2015-01-01

Prostatic enlargement is a common cause of bladder outlet obstruction in men in Nigeria. Malignant enlargements must be differentiated from benign enlargements for adequate treatment of each patient. High serum total prostate-specific antigen (tPSA) levels suggest malignancy, but some of the biopsies done due to a serum tPSA value >4 ng/mL would be negative for malignancy because of the low specificity of tPSA for prostate cancer. This study aims to compare the histologic findings of all prostate specimens obtained from core needle biopsy, open simple prostatectomy, and transurethral resection of the prostate with the respective serum tPSA values in an attempt to decipher the role of serum tPSA in the management of these patients. The case notes of patients attended to from April 2009 to March 2012 were analyzed. Essentially, the age of the patient, findings on digital rectal examination, abdominopelvic ultrasonography report on the prostate, serum tPSA, and histology reports from biopsy or prostatectomy specimens as indicated were extracted for analysis. The relationship between age, findings on digital rectal examination, serum tPSA, abdominopelvic ultrasonography report, and histology are compared. A statistically significant relationship existed between a malignant histology and age 65 years and older, suspicious findings on digital rectal examination, suspicious ultrasonography findings, and serum tPSA >10 ng/mL, but not tPSA >4 ng/mL. In Nigerian patients with symptomatic prostate enlargement, serum tPSA should be seen as a continuum with increasing risk of prostate malignancy.

Unindicated multiphase CT scans in non-traumatic abdominal emergencies for women of reproductive age: a significant source of unnecessary exposure.

PubMed

Giannitto, Caterina; Campoleoni, Mauro; Maccagnoni, Sara; Angileri, Alessio Salvatore; Grimaldi, Maria Carmela; Giannitto, Nino; De Piano, Francesca; Ancona, Eleonora; Biondetti, Pietro Raimondo; Esposito, Andrea Alessandro

2018-03-01

To determine the frequency of unindicated CT phases and the resultant excess of absorbed radiation doses to the uterus and ovaries in women of reproductive age who have undergone CT for non-traumatic abdomino-pelvic emergencies. We reviewed all abdomino-pelvic CT examinations in women of reproductive age (40 years or less), between 1 June 2012 and 31 January 2015. We evaluated the appropriateness of each CT phase on the basis of clinical indications, according to ACR appropriateness criteria and evidence-based data from the literature. The doses to uterus and ovaries for each phase were calculated with the CTEXPO software, taking into consideration the size-specific dose estimate (SSDE) after measuring the size of every single patient. The final cohort was composed of 76 female patients with an average age of 30 (from 19 to 40 years). In total, 197 CT phases were performed with an average of 2.6 phases per patient. Out of these, 93 (47%) were unindicated with an average of 1.2 inappropriate phases per patient. Unindicated scans were most frequent for appendicitis and unlocalized abdominal pain. The excesses of mean radiation doses to the uterus and ovaries due to unindicated phases were, respectively, of 38 and 33 mSv per patient. In our experience, unindicated additional CT phases were numerous with a significant excess radiation dose without an associated clinical benefit. This excess of radiation could have been avoided by widespread adoption of the ACR appropriateness criteria and evidence-based data from the literature.

Glossary of Internet Terms.

ERIC Educational Resources Information Center

Microcomputers for Information Management, 1995

1995-01-01

Provides definitions for 71 terms related to the Internet, including Archie, bulletin board system, cyberspace, e-mail (electronic mail), file transfer protocol, gopher, hypertext, integrated services digital network, local area network, listserv, modem, packet switching, server, telnet, UNIX, WAIS (wide area information servers), and World Wide…

Intelligence Differentiation in Adult Samples.

ERIC Educational Resources Information Center

Abad, Francisco J.; Colom, Robert; Juan-Espinosa, Manuel; Garcia, Luis F.

2003-01-01

Results for 3,340 participants taking a battery of cognitive tests and an analysis of the Spanish standardization of the Wechsler Adult Intelligence Scale-III support the differentiation of intelligence across the range of ability, with WAIS-III results more supportive of the differentiation theory. (SLD)

Drought Assessment over the Four Major River Basins of India using GRACE-based estimates of Water Availability

NASA Astrophysics Data System (ADS)

Sinha, D.; Syed, T. H.

2017-12-01

Drought is a natural disaster that has mutilating consequences over agriculture, ecosystems, economy and the society. Over the past few decades, drought related catastrophe, associated with global climate change, has escalated all across the world. Identification and analysis of drought utilizing individual hydrologic variables may be inadequate owing to the multitude of factors that are associated with the phenomenon. Therefore it is crucial to develop techniques that warrant comprehensive monitoring and assessment of droughts. In this study we propose a novel drought index (Water Availability Index (WAI)) that comprehends all the aspects of meteorologic, agricultural and hydrologic droughts. The proposed framework underscores the conceptualization and utilization of water availability, quantified as an integrated estimate of land water storage, using Gravity Recovery and Climate Experiment (GRACE) observations, and precipitation. The methodology is employed over four major river basins of India (i.e. Ganga, Krishna, Godavari and Mahanadi) for a period of 155 months (April 2002 to February 2015). Results exhibit the potential of the propounded index (WAI) to recognize drought events and impart insightful quantification of drought severity. WAI also demonstrates enhanced outcomes in comparison to other commonly used drought indices like PDSI, SPI, SPEI and SRI. In general there are at least three major drought periods with intensities ranging from moderate to severe in almost all river basins. The longest drought period, extending for 27 months, from September 2008 to November 2010, is observed in the Mahanadi basin. Results from this study confirm the potential of this technique as an effective tool for the characterization of drought at large spatial scales, which will only excel with better quantification and extended availability of terrestrial water storage observations from the GRACE-Follow On mission.

Neurocognitive function in clinically stable individuals with long-term bipolar I disorder: Comparisons with schizophrenia patients and controls.

PubMed

Lin, Pei-Yun; Wang, Peng-Wei; Chen, Cheng-Sheng; Yen, Cheng-Fang

2017-05-01

This study compared the levels of the five domains of neurocognitive function-executive function, attention, memory, verbal comprehension, and perceptual organization-among clinically stable individuals with long-term bipolar I disorder, individuals with long-term schizophrenia, and a group of controls. We recruited a total of 93 clinically stable individuals with bipolar I disorder, 94 individuals with schizophrenia, and 106 controls in this study. Their neurocognitive function was measured using a series of neurocognitive function tests: the Wechsler Adult Intelligence Scale-Third Edition (WAIS-III), Line Cancellation Test, Visual Form Discrimination, Controlled Oral Word Association Test, Wisconsin Card Sorting Test, Continuous Performance Task, and Wechsler Memory Scale-Third Edition. Neurocognitive function was compared among the three groups through a multivariate analysis of variance. The results indicated that when the effect of age was controlled, clinically stable individuals with bipolar I disorder and those with schizophrenia demonstrated poor neurocognitive function on all tests except for the WAIS-III Similarity and Information and the Line Cancellation Test. The individuals with bipolar I disorder had similar levels of neurocognitive function compared with the schizophrenia group, but higher levels of neurocognitive function on the WAIS-III Comprehension, Controlled Oral Word Association Test, and Wechsler Memory Scale-Third Edition Auditory Immediate and Delayed Index and Visual Immediate and Delayed Index. The conclusions of this study suggest that compared with controls, individuals with long-term bipolar I disorder and those with long-term schizophrenia have poorer neurocognitive function, even when clinically stable. Individuals with long-term bipolar I disorder and those with long-term schizophrenia have similar levels of deficits in several domains of neurocognitive function. Copyright © 2017. Published by Elsevier Taiwan.

Behavioral health care for adolescents with poorly controlled diabetes via Skype: does working alliance remain intact?

PubMed

Freeman, Kurt A; Duke, Danny C; Harris, Michael A

2013-05-01

Increasingly various technologies are being tested to deliver behavioral health care. Delivering services via videoconferencing shows promise. Given that the patient-provider relationship is a strong predictor of patient adherence to medical regimens, addressing relationship quality when services are not delivered face-to-face is critical. To that end, we compared the therapeutic alliance when behavioral health care was delivered to youth with poorly controlled type 1 diabetes mellitus (T1DM) and their caregivers in-clinic with the same services delivered via Internet-based videoconferencing (i.e., Skype™). Seventy-one adolescents with poorly controlled T1DM (hemoglobin A1c ≥9%) and one of their caregivers received up to 10 sessions of a family-based behavioral health intervention previously shown to improve adherence to diabetes regimens and family functioning; 32 were randomized to the Skype condition. Youth and caregivers completed the working alliance inventory (WAI), a 36-item measure of therapeutic alliance, at the end of treatment. Additionally, the number of behavioral health sessions completed was tracked. No significant differences in WAI scores were found for those receiving behavioral health care via Skype versus in-clinic. Youth WAI goal and total scores were significantly associated with the number of sessions completed for those in the clinic group. Behavioral health can be delivered to youth with T1DM via Internet-based videoconferencing without significantly impacting the therapeutic relationship. Thus, for those adolescents with T1DM who require specialized behavioral health care that targets T1DM management, Internet-based teleconferencing represents a viable alternative to clinic-based care. © 2013 Diabetes Technology Society.

Association of Structural Global Brain Network Properties with Intelligence in Normal Aging

PubMed Central

Fischer, Florian U.; Wolf, Dominik; Scheurich, Armin; Fellgiebel, Andreas

2014-01-01

Higher general intelligence attenuates age-associated cognitive decline and the risk of dementia. Thus, intelligence has been associated with cognitive reserve or resilience in normal aging. Neurophysiologically, intelligence is considered as a complex capacity that is dependent on a global cognitive network rather than isolated brain areas. An association of structural as well as functional brain network characteristics with intelligence has already been reported in young adults. We investigated the relationship between global structural brain network properties, general intelligence and age in a group of 43 cognitively healthy elderly, age 60–85 years. Individuals were assessed cross-sectionally using Wechsler Adult Intelligence Scale-Revised (WAIS-R) and diffusion-tensor imaging. Structural brain networks were reconstructed individually using deterministic tractography, global network properties (global efficiency, mean shortest path length, and clustering coefficient) were determined by graph theory and correlated to intelligence scores within both age groups. Network properties were significantly correlated to age, whereas no significant correlation to WAIS-R was observed. However, in a subgroup of 15 individuals aged 75 and above, the network properties were significantly correlated to WAIS-R. Our findings suggest that general intelligence and global properties of structural brain networks may not be generally associated in cognitively healthy elderly. However, we provide first evidence of an association between global structural brain network properties and general intelligence in advanced elderly. Intelligence might be affected by age-associated network deterioration only if a certain threshold of structural degeneration is exceeded. Thus, age-associated brain structural changes seem to be partially compensated by the network and the range of this compensation might be a surrogate of cognitive reserve or brain resilience. PMID:24465994

A snow pack source of aldehydes and acetone in West Antarctica between 76 and 90 degrees S

NASA Astrophysics Data System (ADS)

Frey, M. M.; Bales, R. C.; Belle-Oudry, D.

2009-04-01

The investigation of snow-atmosphere exchange of many chemical species driven by physical and photochemical processes is key for understanding atmospheric chemistry above snow covered regions and has important implications for ice core interpretation. A number of recent field and modeling studies indicates that a source of aldehydes and ketones exists in polar snowpacks, and the emission of these species may significantly impact organic and HO2 radical levels in the overlying boundary layer. However, most of the studies took place in the northern hemisphere and only few data are available from Antarctica. Here we present new measurements from the US International Trans-Antarctic Scientific Expedition (ITASE) carried out in summers of 2000-2003. 1-2 day average mixing ratios of formaldehyde (CH2O), acetaldehyde (CH3CHO) and acetone (CH3COCH3) were determined in ambient and firn air across the West Antarctic Ice Sheet (WAIS) between 76 °S and 90 °S. Organic chemical species were collected on 2,4-Dinitrophenylhydrazine (DNPH) filter cartridges and analyzed after elution using HPLC. Median (range) ambient levels of CH2O, CH3CHO and CH3COCH3 were 65 (15-205) pptv, 35 (10-195) pptv and 65 (25-150) pptv, respectively. Firn air concentrations of CH2O and CH3CHO were increased up to 15fold compared to ambient air, suggesting significant emission fluxes, while CH3COCH3 gradients between the air above and below the snow surface were less pronounced.. We discuss implications for the oxidation capacity of the WAIS boundary layer and for the interpretation of ongoing surface studies at the WAIS Divide deep coring site.

Individual features, working conditions and work injuries are associated with work ability among nursing professionals.

PubMed

Fischer, Frida Marina; Martinez, Maria Carmen

2013-01-01

To investigate factors associated with work ability among nursing professionals. They comprised 514 nursing professionals (83.8% of the total number of workers) from a hospital in São Paulo, Brazil. In 2009, we conducted a cross-sectional study that was a part of a 5-year planned cohort study initiated in 2008. We administered a comprehensive questionnaire to the participants in order to obtain data on their sociodemographic characteristics, lifestyles, and working conditions. The questionnaire also contained the Brazilian versions of the following: the Job Stress Scale (JSS), Effort-Reward Imbalance (ERI) Questionnaire, Work-Related Activities That May Contribute To Job-Related Pain and/or Injury (WRAPI), and Work Ability Index (WAI). The results were analyzed using descriptive, bivariate, and multivariate linear regression analyses. On the WAI, 74.9% of the workers obtained a score of over 40 points (score range 7-49); the mean score was 42.3 points (SD=4.5). The final multivariate model showed that lower WAI scores were related to the work-related outcome, which was work injury, and the following individual characteristics and working conditions: body mass index (p=0.001), sex (female; p=0.002), sedentariness (p < 0.001), time in the profession (p=0.005), social support at work (p=0.003), effort-reward ratio (p=0.001), violence at work (p=0.005), WRAPI score (p < 0.001), and work injuries (yes; p=0.001). Various factors were associated with work ability. The results showed that a number of variables should be considered when planning and implementing actions to maintain or improve work ability among nursing professionals.

Cognitive functions in Parkinson's disease: relation to disease severity and hallucination.

PubMed

Wakamori, Takaaki; Agari, Takashi; Yasuhara, Takao; Kameda, Masahiro; Kondo, Akihiko; Shinko, Aiko; Sasada, Susumu; Sasaki, Tatsuya; Furuta, Tomohisa; Date, Isao

2014-04-01

We wished to relate severity of Parkinson's disease (PD) with cognitive function in relation to cerebral blood flow (CBF). Eighty-one consecutive PD patients were enrolled in this study. We used Mini-Mental State Examination (MMSE) and Wechsler Adult Intelligence Scale-Third edition (WAIS-III) to evaluate cognitive functions, and three-dimensional stereotactic ROI template (3DSRT) and Statistical Parametric Mapping (SPM) 8 to evaluate single photon emission CT (SPECT) recordings of regional CBF. The mean MMSE score of PD patients was 27.4 ± 2.4. The scores of most patients were higher than 23/30. On the other hand, the mean Full-scale IQ of PD patients was 88.4 ± 17.3 in WAIS-III, which was lower than that of normal controls. In particular, visuospatial function score of most patients was lower. There was significant correlation between cognitive scores and Hoehn & Yahr stage and hallucinatory episodes. PD Patients with stage III and IV showed significant deterioration in cognitive functions compared to stage II patients. Analysis of CBF revealed relative reductions in perfusion in the cerebral cortex relative to that in normal control. SPM 8 showed that cognitive functions in PD patients were positively correlated with rCBF in the thalamus and cingulate gyrus. This is the study to demonstrate the cognitive impairments in PD patients using WAIS-III. Visuospatial dysfunction might be caused by decrease in rCBF in the parietal and occipital lobes and dorsolateral prefrontal cortex. The severity of cognitive impairments in PD patients was correlated with disease severity and hallucinatory episodes. Copyright © 2014 Elsevier Ltd. All rights reserved.

Future Antarctic bed topography and its implications for ice sheet dynamics

NASA Astrophysics Data System (ADS)

Adhikari, Surendra; Ivins, Erik; Larour, Eric; Seroussi, Helene; Morlighem, Mathieu; Nowicki, Sophie

2014-05-01

A recently improved ice loading history suggests that the Antarctic Ice Sheet (AIS) has been generally losing its mass since the last glacial maximum. In a sustained warming climate, the AIS is predicted to retreat at a greater pace primarily via melting beneath the ice shelves. We employ the glacial isostatic adjustment (GIA) capability of the Ice Sheet System Model (ISSM) to combine these past and future ice loadings and provide the new solid Earth computations for the AIS. We find that the past loading is relatively less important than future loading on the evolution of the future bed topography. Our computations predict that the West Antarctic Ice Sheet (WAIS) may uplift by a few meters and a few tens of meters at years 2100 and 2500 AD, respectively, and that the East Antarctic Ice Sheet (EAIS) is likely to remain unchanged or subside minimally except around the Amery Ice Shelf. The Amundsen Sea Sector of WAIS in particular is predicted to rise at the greatest rate; one hundred years of ice evolution in this region, for example, predicts that the coastline of Pine Island Bay approaches roughly 45 mm/yr in viscoelastic vertical motion. Of particular importance, we systematically demonstrate that the effect of a pervasive and large GIA uplift in the WAIS is associated with the flattening of reverse bed, reduction of local sea depth, and thus the extension of grounding line (GL) towards the continental shelf. Using the 3-D higher-order ice flow capability of ISSM, such a migration of GL is shown to inhibit the ice flow. This negative feedback between the ice sheet and the solid Earth may promote the stability to marine portions of the ice sheet in the future.

Coliphage and indigenous phage in Mamala Bay, Oahu, Hawaii.

PubMed

Paul, J H; Rose, J B; Jiang, S C; London, P; Xhou, X; Kellogg, C

1997-01-01

Public concern over the discharge of primarily treated sewage by two offshore outfalls in Mamala Bay, Oahu, prompted a multidisciplinary study to determine the impact of such activities on the water quality in the bay and at adjacent recreational beaches. As part of this study, we determined the abundance of coliphage as an indicator of fecal pollution along with total viral direct counts and phages infective for Vibrio parahaemoltyicus 16 at stations in Mamala Bay in four quarterly samplings over 13 months. Coliphage (< 1 to 1.2 x 10(3)/liter) were found during each quarterly sampling along an offshore transect to the Sand Island waste treatment facility outfall. The nonpoint coastal stations (Pearl Harbor, Ala Wai Canal, and Ke'ehi Lagoon) had high levels of coliphage during the storm event sampling in February 1994 but much lower levels or none when sampled during dry weather. Coliphage were absent at all samplings at Waikiki Beach and at the control station off Diamond Head. Viral direct counts in eutrophic coastal stations (Pearl Harbor, Ke'ehi Lagoon, Ala Moana Beach, and Ala Wai canal) averaged 10(9)/liter, while counts at offshore stations ranged from 9 x 10(7) to 1 x 10(9) viruses/liter, values similar to those for other marine environments. Vibriophage were found mainly in eutrophic coastal environments (Ala Wai Canal, Pearl Harbor, and Ke'ehi Lagoon) and at the Sand Island Transect stations D1 and D2. The greatest abundance was found during the storm event (February 1994) sampling. These results suggest that the Sand Island outfall influenced the water quality of the immediate surrounding waters but had little effect on the quality of the recreational beaches. Nonpoint discharge sources appeared to be more important in the distribution of fecal indicators in the coastal zone.

Behavioral Health Care for Adolescents with Poorly Controlled Diabetes via Skype: Does Working Alliance Remain Intact?

PubMed Central

Freeman, Kurt A.; Duke, Danny C.; Harris, Michael A.

2013-01-01

Background: Increasingly various technologies are being tested to deliver behavioral health care. Delivering services via videoconferencing shows promise. Given that the patient–provider relationship is a strong predictor of patient adherence to medical regimens, addressing relationship quality when services are not delivered face-to-face is critical. To that end, we compared the therapeutic alliance when behavioral health care was delivered to youth with poorly controlled type 1 diabetes mellitus (T1DM) and their caregivers in-clinic with the same services delivered via Internet-based videoconferencing (i.e., Skype™). Methods: Seventy-one adolescents with poorly controlled T1DM (hemoglobin A1c ≥9%) and one of their caregivers received up to 10 sessions of a family-based behavioral health intervention previously shown to improve adherence to diabetes regimens and family functioning; 32 were randomized to the Skype condition. Youth and caregivers completed the working alliance inventory (WAI), a 36-item measure of therapeutic alliance, at the end of treatment. Additionally, the number of behavioral health sessions completed was tracked. Results: No significant differences in WAI scores were found for those receiving behavioral health care via Skype versus in-clinic. Youth WAI goal and total scores were significantly associated with the number of sessions completed for those in the clinic group. Conclusion: Behavioral health can be delivered to youth with T1DM via Internet-based videoconferencing without significantly impacting the therapeutic relationship. Thus, for those adolescents with T1DM who require specialized behavioral health care that targets T1DM management, Internet-based teleconferencing represents a viable alternative to clinic-based care. PMID:23759406

Untangling Your Web.

ERIC Educational Resources Information Center

Coombs, Norman

2000-01-01

Provides an overview of universal Web design and discusses guidelines developed by the Web access initiative (WAI) that focus on the access needs of Web users with disabilities. Highlights include barriers for people with print disabilities or motor impairments; the role of libraries; and resources to assist Web designers. (LRW)

Personality and Psychopathology in African Unaccompanied Refugee Minors: Repression, Resilience and Vulnerability

ERIC Educational Resources Information Center

Huemer, Julia; Volkl-Kernstock, Sabine; Karnik, Niranjan; Denny, Katherine G.; Granditsch, Elisabeth; Mitterer, Michaela; Humphreys, Keith; Plattner, Belinda; Friedrich, Max; Shaw, Richard J.; Steiner, Hans

2013-01-01

Examining personality and psychopathological symptoms among unaccompanied refugee minors (URMs), we measured intra-individual dimensions (repression and correlates thereof) usually associated with resilience. Forty-one URMs completed the Weinberger Adjustment Inventory (WAI), assessing personality, and the Youth Self-Report (YSR), describing…

Visuospatial characteristics of an elderly Chinese population: results from the WAIS-R block design test.

PubMed

Yin, Shufei; Zhu, Xinyi; Huang, Xin; Li, Juan

2015-01-01

Visuospatial deficits have long been recognized as a potential predictor of dementia, with visuospatial ability decline having been found to accelerate in later stages of dementia. We, therefore, believe that the visuospatial performance of patients with mild cognitive impairment (MCI) and dementia (Dem) might change with varying visuospatial task difficulties. This study administered the Wechsler Adult Intelligence Scale-Revised (WAIS-R) Block Design Test (BDT) to determine whether visuospatial ability can help discriminate between MCI patients from Dem patients and normal controls (NC). Results showed that the BDT could contribute to the discrimination between MCI and Dem. Specifically, simple BDT task scores could best distinguish MCI from Dem patients, while difficult BDT task scores could contribute to discriminating between MCI and NC. Given the potential clinical value of the BDT in the diagnosis of Dem and MCI, normative data stratified by age and education for the Chinese elderly population are presented for use in research and clinical settings.

Changes in the functional properties and antinutritional factors of extruded hard-to-cook common beans (Phaseolus vulgaris, L.).

PubMed

Batista, Karla A; Prudêncio, Sandra H; Fernandes, Kátia F

2010-04-01

The biochemical and functional properties of 2 hard-to-cook common bean cultivars (Phaseolus vulgaris, L.) were investigated after the extrusion process. Beans of BRS pontal and BRS grafite cultivars were milled and extruded at 150 degrees C, with a compression ratio screw of 3 : 1, 5-mm die, and screw speed of 150 rpm. Extrudate flours were evaluated for water solubility (WS), water absorption index (WAI), oil absorption capacity (OAC), foaming capacity (FC), emulsifying activity (EA), antinutritional factors, and in vitro protein and starch digestibility. Results indicated that the extrusion significantly decreased antinutrients such as phytic acid, lectin, alpha-amylase, and trypsin inhibitors, reduced the emulsifying capacity and eliminated the FC in both BRS pontal and BRS grafite cultivars. In addition, the WS, WAI, and in vitro protein and starch digestibility were improved by the extrusion process. These results indicate that it is possible to produce new extruded products with good functional and biochemical properties from these common bean cultivars.

Effect of extrusion process parameters and pregelatinized rice flour on physicochemical properties of ready-to-eat expanded snacks.

PubMed

Gat, Yogesh; Ananthanarayan, Laxmi

2015-05-01

Present study was conducted to investigate effects of pregelatinized rice flour and extrusion process parameters such as feed moisture (16-19 %), die temperature (115-145 °C) and screw speed (150-250 rpm) on physicochemical properties of ready-to-eat expanded snacks by using co-rotating twin-screw extruder. Higher die temperature increased extrudate density and WSI but reduced die pressure, torque and expansion. Increased feed moisture content resulted in extrudates with increased density, WAI and hardness but reduced die pressure, expansion and WSI. Screw speed was found to have no significant effect on expansion and hardness of extrudates, while increase in screw speed resulted in increased WAI of extrudates and reduced torque of extrudates. Effect of pregelatinized rice flour on extrudate expansion and hardness was analysed at 16 % feed moisture, 135 °C die temperature and 150 rpm screw speed. Use of pregelatinized rice flour increased expansion while it reduced hardness of extrudates.

High geothermal heat flux measured below the West Antarctic Ice Sheet.

PubMed

Fisher, Andrew T; Mankoff, Kenneth D; Tulaczyk, Slawek M; Tyler, Scott W; Foley, Neil

2015-07-01

The geothermal heat flux is a critical thermal boundary condition that influences the melting, flow, and mass balance of ice sheets, but measurements of this parameter are difficult to make in ice-covered regions. We report the first direct measurement of geothermal heat flux into the base of the West Antarctic Ice Sheet (WAIS), below Subglacial Lake Whillans, determined from the thermal gradient and the thermal conductivity of sediment under the lake. The heat flux at this site is 285 ± 80 mW/m(2), significantly higher than the continental and regional averages estimated for this site using regional geophysical and glaciological models. Independent temperature measurements in the ice indicate an upward heat flux through the WAIS of 105 ± 13 mW/m(2). The difference between these heat flux values could contribute to basal melting and/or be advected from Subglacial Lake Whillans by flowing water. The high geothermal heat flux may help to explain why ice streams and subglacial lakes are so abundant and dynamic in this region.

Changes in FKBP5 expression and memory functions during cognitive-behavioral therapy in posttraumatic stress disorder: a preliminary study.

PubMed

Szabó, Csilla; Kelemen, Oguz; Kéri, Szabolcs

2014-05-21

Posttraumatic stress disorder (PTSD) is characterized by hyperarousal, flashbacks, avoidance, and memory dysfunctions. Although psychotherapy improves the clinical symptoms, its effect on memory has not been explored. In addition, there is no information about gene expression changes related to hippocampal functions. We assessed PTSD patients (n=20) using the Wechsler Memory Scale-Revised (WAIS-R) and a paired associates learning (PAL) test, as well as changes in blood FK506 binding protein (FKBP5) mRNA expression before and after cognitive behavioral therapy (CBT). Results revealed that before CBT PTSD patients were impaired on WAIS-R delayed recall, attention/concentration, and PAL compared with trauma-exposed control subjects (n=20). These memory dysfunctions showed a significant improvement after CBT. Better performance on the PAL test correlated with enhanced blood FKBP5 mRNA expression. These results suggest that elevated FKBP5 expression during CBT is related to improved associative memory linked to the hippocampal formation. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Wechsler Adult Intelligence Scale-IV Dyads for Estimating Global Intelligence.

PubMed

Girard, Todd A; Axelrod, Bradley N; Patel, Ronak; Crawford, John R

2015-08-01

All possible two-subtest combinations of the core Wechsler Adult Intelligence Scale-IV (WAIS-IV) subtests were evaluated as possible viable short forms for estimating full-scale IQ (FSIQ). Validity of the dyads was evaluated relative to FSIQ in a large clinical sample (N = 482) referred for neuropsychological assessment. Sample validity measures included correlations, mean discrepancies, and levels of agreement between dyad estimates and FSIQ scores. In addition, reliability and validity coefficients were derived from WAIS-IV standardization data. The Coding + Information dyad had the strongest combination of reliability and validity data. However, several other dyads yielded comparable psychometric performance, albeit with some variability in their particular strengths. We also observed heterogeneity between validity coefficients from the clinical and standardization-based estimates for several dyads. Thus, readers are encouraged to also consider the individual psychometric attributes, their clinical or research goals, and client or sample characteristics when selecting among the dyadic short forms. © The Author(s) 2014.

Effects of practice on the Wechsler Adult Intelligence Scale-IV across 3- and 6-month intervals.

PubMed

Estevis, Eduardo; Basso, Michael R; Combs, Dennis

2012-01-01

A total of 54 participants (age M = 20.9; education M = 14.9; initial Full Scale IQ M = 111.6) were administered the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) at baseline and again either 3 or 6 months later. Scores on the Full Scale IQ, Verbal Comprehension, Working Memory, Perceptual Reasoning, Processing Speed, and General Ability Indices improved approximately 7, 5, 4, 5, 9, and 6 points, respectively, and increases were similar regardless of whether the re-examination occurred over 3- or 6-month intervals. Reliable change indices (RCI) were computed using the simple difference and bivariate regression methods, providing estimated base rates of change across time. The regression method provided more accurate estimates of reliable change than did the simple difference between baseline and follow-up scores. These findings suggest that prior exposure to the WAIS-IV results in significant score increments. These gains reflect practice effects instead of genuine intellectual changes, which may lead to errors in clinical judgment.

Profile of cognitive function in adults with duchenne muscular dystrophy.

PubMed

Ueda, Yukihiko; Suwazono, Shugo; Maedo, Sino; Higuchi, Itsuro

2017-03-01

Several studies have examined intellectual functioning of boys with duchenne muscular dystrophy (DMD). However, little is known about the remaining cognitive weaknesses in adults with DMD. The purpose of this study was to investigate the profile of cognitive functioning that is characteristics of adults with DMD. Twenty-four subscales from the Wechsler Adult Intelligence Scale III (WAIS-III), the Clinical Assessment for Attention (CAT), and the Wechsler Memory Scale Revised (WMS-R) were used to assess participants with DMD (N=15; mean age=30.4years). Scores for Picture Completion, Arithmetic, Matrix Reasoning, Symbol Search, Letter-Number Sequencing, and Digit Span of the WAIS-III; all CAT scores, and Logical Memory and Delayed Logical Memory from the WMS-R were significantly deficient in adults with DMD in comparison to the normal population. The ability to sequentially process auditory and visual information remains impaired in adults with DMD. Copyright © 2016 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

Association Among Sociodemograhic Factors, Work Ability, Health Behavior, and Mental Health Status for Young People After Prolonged Unemployment.

PubMed

Lappalainen, Kirsi; Manninen, Pirjo; Räsänen, Kimmo

2017-02-01

The purpose of this study was to explore the associations of prolonged unemployment, health, and work ability among young workers using data from the 2008-2010 Occupational Health Counselling project in Kuopio, Eastern Finland. The total sample for this study was 190 young unemployed adults. The questionnaire included the Work Ability Index (WAI), the Beck Depression Inventory, the Alcohol Use Disorders Identification Test, and the Occupational Health Counselling Survey. Multivariate analyses revealed that men had a higher prevalence of prolonged unemployment than women. Using drugs for purposes other than treatment was associated independently with an increased prevalence of prolonged unemployment. Low WAI scores were associated with a higher prevalence of prolonged unemployment. This study showed that attention should be paid to male workers, those who have poor or moderate work ability and workers who use drugs. Young unemployed workers should be recognized at an early stage. A comprehensive, flexible network of community resources is essential to support young unemployed adults.

How age affects memory task performance in clinically normal hearing persons.

PubMed

Vercammen, Charlotte; Goossens, Tine; Wouters, Jan; van Wieringen, Astrid

2017-05-01

The main objective of this study is to investigate memory task performance in different age groups, irrespective of hearing status. Data are collected on a short-term memory task (WAIS-III Digit Span forward) and two working memory tasks (WAIS-III Digit Span backward and the Reading Span Test). The tasks are administered to young (20-30 years, n = 56), middle-aged (50-60 years, n = 47), and older participants (70-80 years, n = 16) with normal hearing thresholds. All participants have passed a cognitive screening task (Montreal Cognitive Assessment (MoCA)). Young participants perform significantly better than middle-aged participants, while middle-aged and older participants perform similarly on the three memory tasks. Our data show that older clinically normal hearing persons perform equally well on the memory tasks as middle-aged persons. However, even under optimal conditions of preserved sensory processing, changes in memory performance occur. Based on our data, these changes set in before middle age.

Wide Area Information Servers: An Executive Information System for Unstructured Files.

ERIC Educational Resources Information Center

Kahle, Brewster; And Others

1992-01-01

Describes the Wide Area Information Servers (WAIS) system, an integrated information retrieval system for corporate end users. Discussion covers general characteristics of the system, search techniques, protocol development, user interfaces, servers, selective dissemination of information, nontextual data, access to other servers, and description…

New Horizons in Education, Number 37.

ERIC Educational Resources Information Center

New Horizons in Education, 1996

1996-01-01

The journal issue contains articles in either Chinese or English, each with abstracts in both languages. They include: "'Every Person Is a Creative Being': Teaching Method Designed To Cultivate Creativity from the Perspective of Educational Psychology" (Wai Man Lee); "Sex Differences in Problem Behaviour and the Self-Concept: An…

Interfaces for Distributed Systems of Information Servers.

ERIC Educational Resources Information Center

Kahle, Brewster; And Others

1992-01-01

Describes two systems--Wide Area Information Servers (WAIS) and Rosebud--that provide protocol-based mechanisms for accessing remote full-text information servers. Design constraints, human interface design, and implementation are examined for five interfaces to these systems developed to run on the Macintosh or Unix terminals. Sample screen…

New Horizons in Education, 2000.

ERIC Educational Resources Information Center

Ho, Kwok Keung, Ed.

2000-01-01

This document contains the May and November 2000 issues of "New Horizons in Education," with articles in English and Chinese. The May issue includes the following articles: "A Key to Successful Environmental Education: Teacher Trainees' Attitude, Behaviour, and Knowledge" (Kevin Chung Wai Lui, Eric Po Keung Tsang, Sing Lai…

The tephrostratigraphy of Mt. Berlin volcano, Antarctica: Integrating blue ice tephra and ice core tephra records

NASA Astrophysics Data System (ADS)

Iverson, N. A.; Dunbar, N. W.; McIntosh, W. C.; Kurbatov, A.

2016-12-01

Reconstructing volcanic activity in Antarctica is difficult because of the limited outcrop exposure. However, ice is an excellent medium for sampling tephra, allowing for a more complete eruptive record than can be found in other depositional environments. Furthermore, because of low ambient temperature, glass shards trapped in ice remain unaltered and unhydrated. Mt. Berlin is an ice covered volcano in Marie Byrd Land, Antarctica, and, because of heavy glaciation, eruptive records on the volcano itself are sparse. Here, we present the integration of two different records of Mt. Berlin volcanism: the blue ice record found at Mt. Moulton (Dunbar et al., 2008) and the ice core record from the WAIS Divide ice core. Tephra from Mt. Berlin are also found in other ice and marine core records, and these have been correlated and integrated into the combined volcanic record. The Mt. Moulton blue ice area is located 30 km from Mt. Berlin and hosts a fabulous tephra record spanning the last 500 ka. A total of 36 tephra from Mt. Berlin were sampled in stratigraphic order and nine were directly dated by 40Ar/39Ar dating method. Twenty five tephra from WAIS Divide have been analyzed and are geochemically similar to Mt. Berlin with ice core ages dating back to 70 ka. The two tephra records were integrated using their respective timescales. In locations where the Mt. Moulton record does not have precise chronology, the δ18O records from Mt. Moulton (Popp, 2008) and WAIS (WAIS, 2015) were used to integrate the stratigraphy. In total 61 tephra from both ice sections provide an excellent record of the magmatic evolution of Mt. Berlin over the past 500 ka. EMP analyses on glass shards show a gradual change in Fe and S over time. Most of the other major elements remain relatively unchanged. The trend in Fe and S could be produced by progressive tapping of a single, stratified magma chamber, but the long duration of volcanism makes this unlikely. We instead favor small batches of progressively more primitive melts being generated over time. Thirty nine of the tephra have been erupted within the past 100 ka with the majority (25) of them being erupted between 40 ka and 20 ka. The resolution in eruptive frequency is unparalleled and provides many stratigraphic markers that can be correlated throughout West Antarctica, which are useful in climate research.

Estimated Full Scale IQ in an Adult Heroin Addict Population.

ERIC Educational Resources Information Center

Chastain, Robert L.; And Others

The research concerning intellectual functioning in addict populations has not addressed basic questions concerning why and how intelligence quotients (IQ) might be related to drug addiction. A study was undertaken to estimate intellectual functioning based upon a demographic profile for Wechsler Adult Intelligence Scale-Revised (WAIS-R) Full…

76 FR 5137 - Initiation of Antidumping and Countervailing Duty Administrative Reviews

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-28

... Co., Ltd. Cheng Du Wai Yuan Bee Products Co., Ltd. Chengdu Stone Dynasty Art Stone Damco China Limited Qingdao Branch Dongtai Peak Honey Industry Co., Ltd. Eurasia Bee's Products Co., Ltd. Feidong...., Ltd. Inner Mongolia Altin Bee-Keeping Inner Mongolia Youth Trade Development Co., Ltd. Jiangsu Cereals...

The Relative Utility of the Shipley-Hartford Scale: Prediction of WAIS-R IQ.

ERIC Educational Resources Information Center

Heinemann, Allen W.; And Others

1985-01-01

Examined Shipley-Hartford Scale effectiveness in predicting Wechsler Adult Intelligence Scale-Revised Full Scale intelligence quotients (IQ) in hospital patients (N=156). Analyses revealed overestimation of below average Full Scale IQs, underestimation of above average IQs. Advanced age was associated with low conceptual quotients, suggesting that…

Digit Symbol Performance in Mild Dementia and Depression.

ERIC Educational Resources Information Center

Hart, Robert P.; And Others

1987-01-01

Patients with mild dementia of the Alzheimer's type (DAT), patients with major depression, and normal control subjects completed the Wechsler Adult Intelligence Scale (WAIS) Digit Symbol test of incidental memory. Though mild DAT and depressed patients had equivalent deficits in psychomotor speed, DAT patients recalled fewer digit-symbol items.…

The Malleability of Spatial Skills: A Meta-Analysis of Training Studies

ERIC Educational Resources Information Center

Uttal, David H.; Meadow, Nathaniel G.; Tipton, Elizabeth; Hand, Linda L.; Alden, Alison R.; Warren, Christopher; Newcombe, Nora S.

2013-01-01

Having good spatial skills strongly predicts achievement and attainment in science, technology, engineering, and mathematics fields (e.g., Shea, Lubinski, & Benbow, 2001; Wai, Lubinski, & Benbow, 2009). Improving spatial skills is therefore of both theoretical and practical importance. To determine whether and to what extent training and…

75 FR 12748 - Ocean Transportation Intermediary License Applicants

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-17

... Line (LA), Inc., 470 Cloverleaf Drive, Unit A&B, Baldwin Park, CA 91706, Officers: Wai (aka Winson) M... Shipping & Logistics, LLC, 10651 SW. 108 Avenue, 3A, Miami, FL 33176, Officers: Lorenzo A. Macias... Individual), Zhenfen Wu, Chairman. Qingfeng Wang dba Global Intertrans Logistics, 200 East Norwood Place, San...

Age Effects on Wechsler Adult Intelligence Scale-Revised Tests.

ERIC Educational Resources Information Center

Sattler, Jerome M.

1982-01-01

Studied age norms for 11 individual Wechsler Adult Intelligence Scale-Revised (WAIS-R) tests. Digit Symbol showed the most decline. Results suggest that fluid intelligence, as measured by the performance scale tests, shows more of a decline with age than crystallized intelligence, as measured by the verbal scale tests. (Author)

Correlation of WAIS IQ in 10 Pairs of Brothers.

ERIC Educational Resources Information Center

Matarazzo, Joseph D.; And Others

1978-01-01

Pairs of brothers were individually examined with Wechsler Adult Intelligence Scale some 10 months apart by an experienced clinical psychologist unaware of the consanguineous relationship. Correlation of .42 for Full Scale IQ is consistent with median correlation reported by Erlenmeyer-Kimling and Jarvik in their 1963 literature review.…

A Comparison of Intellectual and Behavioral Functioning in Older Persons.

ERIC Educational Resources Information Center

Smith, Michael C.; Kramer, Nanette A.

In order to ascertain the extent to which older persons' levels of behavioral functioning parallel their levels of intellectual functioning, 42 female patients, aged 61-99, of an outpatient comprehensive care geriatric clinic, completed the Wechsler Adult Intelligence Scale (WAIS), the Instrumental Activities of Daily Living Scale (IADL), the…

United States Air Force Summary, Fifth Edition

DTIC Science & Technology

1979-03-01

t911 COPPER BAUXITE UNITED STATES ZINC CBROIJJI. C!’ NICKEL SOURCE. CIA -HANDBOOK OF ECONOMIC STATISTICS, 19711 IINC it IANSINESE COBALT IRON().pueUI...Wilson, Charles (TX) Boggs, Lindy (Mrs. Hole)(LA) Benjomin, Adam Jr. (IN) Dicks, Norman D. (WAI McHugh "Mafhew F. (NY) Ginn, So (GA) lehman, Williom

Predictors of Urgent Findings on Abdominopelvic CT in Patients with Crohn's Disease Presenting to the Emergency Department.

PubMed

Jung, Yoon Suk; Park, Dong Il; Hong, Sung Noh; Kim, Eun Ran; Kim, Young Ho; Cheon, Jae Hee; Eun, Chang Soo; Han, Dong Soo; Lee, Chang Kyun; Kim, Jae Hak; Huh, Kyu Chan; Yoon, Soon Man; Song, Hyun Joo; Shin, Jeong Eun; Jeon, Seong Ran

2015-04-01

Patients with Crohn's disease (CD) are frequently exposed to diagnostic radiation, mainly as a result of abdominopelvic computed tomography (APCT) examinations. However, there are limited data on the impact of APCT on clinical management in this population. To investigate clinical predictors of urgent findings on APCT in patients with CD who presented to the emergency department (ED). A retrospective study was performed among patients with CD presenting to 11 EDs with a gastrointestinal complaint. The primary outcome, OPAN (obstruction, perforation, abscess, or non-CD-related urgent findings), included new or worsening CD-related urgent findings or non-CD-related urgent findings that required urgent or emergency treatment. Variables with P < 0.1 in univariate analyses were included in a multivariable logistic regression model. Of the 266 APCTs performed, 103 (38.7 %) had OPAN and 113 (42.5 %) required changes in treatment plan. Stricturing or penetrating disease (odds ratio [OR] 2.72, 95 % confidence interval [CI] 1.21-6.13), heart rate >100 beats/min (OR 2.33, 95 % CI 1.10-4.93), leukocyte count >10,000/mm(3) (OR 4.38, 95 % CI 2.10-9.13), and CRP >2.5 mg/dL (OR 3.11, 95 % CI 1.23-7.86) were identified as the independent predictors of OPAN, whereas biologic agent use (OR 0.37; 95 % CI 0.15-0.90) was identified as the negative predictor in patients with CD. Only 39 % of the APCTs performed in the ED among patients with CD showed urgent findings. Stricturing or penetrating disease, tachycardia, leukocytosis, and high CRP level were predictors of urgent CT findings, while biologic agent use was a negative predictor. To reduce unnecessary radiation exposure, the selection process for CD patients referred for APCT must be improved.

Diagnostic yield of cystoscopy in the evaluation of recurrent urinary tract infection in women.

PubMed

Pagano, Matthew J; Barbalat, Yanina; Theofanides, Marissa C; Edokpolo, Leonard; James, Maxwell B; Cooper, Kimberly L

2017-03-01

Due to a paucity of evidence-based guidelines, anecdotal practice patterns often dictate clinical management of recurrent urinary tract infection (UTI) in women. Our aim was to identify pathologic findings of the urinary tract through cystoscopy and imaging in women with recurrent UTI, and to determine if specific risk factors are associated with a higher rate of abnormal findings. In a single-institutional cohort, cystoscopy was performed for women with recurrent UTI between 1/2010 and 7/2014. All eligible patients were included in a maintained database and those with gross or microscopic hematuria were excluded. Abdominopelvic imaging was recommended and included in study data when completed. Associations between clinical risk factors (history of renal transplant, urogynecologic surgery, or urolithiasis) and abnormal findings were analyzed by Fisher's exact test. A total of 163 women (mean age 60.6 years) were included in final analysis. Abdominopelvic imaging was available in 133 (82%) cases. Cystoscopy identified 9 (5.5%) cases of significant clinical findings. Of these only 5 (3.8%) cases were uniquely identified on cystoscopy and missed on imaging modalities. When imaging was normal, cystoscopy was also normal in 94% of cases. The examined clinical risk factors were not associated with higher risk of abnormal cystoscopy (P = 0.49) or imaging (P = 0.42). Cystoscopy performed solely for recurrent UTI is low yield in patients with normal imaging studies, but a small number of abnormal findings may be missed by foregoing this element of the patient workup. No studied risk factor was predictive of an abnormal workup. Neurourol. Urodynam. 36:692-696, 2017. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Accuracy and Radiation Dose Reduction of Limited-Range CT in the Evaluation of Acute Appendicitis in Pediatric Patients.

PubMed

Jin, Michael; Sanchez, Thomas R; Lamba, Ramit; Fananapazir, Ghaneh; Corwin, Michael T

2017-09-01

The purpose of this article is to determine the accuracy and radiation dose reduction of limited-range CT prescribed from the top of L2 to the top of the pubic symphysis in children with suspected acute appendicitis. We performed a retrospective study of 210 consecutive pediatric patients from December 11, 2012, through December 11, 2014, who underwent abdominopelvic CT for suspected acute appendicitis. Two radiologists independently reviewed the theoretic limited scans from the superior L2 vertebral body to the top of the pubic symphysis, to assess for visualization of the appendix, acute appendicitis, alternative diagnoses, and incidental findings. Separately, the same parameters were assessed on the full scan by the same two reviewers. Whole-body effective doses were determined for the full- and limited-range scans and were compared using the paired t test. The appendix or entire cecum was visualized on the limited scan in all cases, and no cases of acute appendicitis were missed on the simulated limited scan compared with the full scan. Two alternative diagnoses were missed with the limited scan: one case of hydronephrosis and one of acute acalculous cholecystitis. The mean effective dose for the original scan was 5.6 mSv and that for the simulated limited scan was 3.0 mSv, resulting in a dose reduction of 46.4% (p < 0.001). A limited-range CT examination performed from the top of L2 to the top of the pubic symphysis is as accurate as a full-range abdominopelvic CT in evaluating pediatric patients with suspected appendicitis and reduces the dose by approximately 46%.

Impact of patient questionnaires on completeness of clinical information and identification of causes of pain during outpatient abdominopelvic CT interpretation.

PubMed

Doshi, Ankur M; Huang, Chenchan; Ginocchio, Luke; Shanbhogue, Krishna; Rosenkrantz, Andrew B

2017-12-01

To evaluate the impact of questionnaires completed by patients at the time of abdominopelvic CT performed for abdominal pain on the completeness of clinical information and the identification of potential causes of pain, compared with order requisitions alone. 100 outpatient CT examinations performed for the evaluation of abdominal pain were retrospectively reviewed. The specificity of the location of pain was compared between the order requisition and patient questionnaire. An abdominal imaging fellow (Reader 1) and abdominal radiologist (Reader 2) reviewed the examinations independently in two sessions 6 weeks apart (one with only the order requisition and one also with the questionnaire). Readers recorded identified causes of pain and rated their confidence in interpretation (1-5 scale; least to greatest confidence). In 30% of patients, the questionnaire provided a more specific location for pain. Among these, the pain was localized to a specific quadrant in 40%. With having access to the questionnaire, both readers identified additional causes for pain not identified in session 1 (Reader 1, 8.6% [7/81]; Reader 2 5.3% [4/75]). Additional identified causes of pain included diverticulitis, cystitis, peritoneal implants, epiploic appendagitis, osseous metastatic disease, umbilical hernia, gastritis, and SMA syndrome. Confidence in interpretation was significantly greater using the questionnaire for both readers (Reader 1: 4.8 ± 0.6 vs. 4.0 ± 0.5; Reader 2: 4.9 ± 0.3 vs. 4.7 ± 0.5, p < 0.001). Patient questionnaires provide additional relevant clinical history, increased diagnostic yield, and improve radiologists' confidence. Radiology practices are encouraged to implement questionnaires and make these readily available to radiologists at the time of interpretation.

Hip dislocations and concurrent injuries in motor vehicle collisions.

PubMed

Cooper, Joseph; Tilan, Justin; Rounds, Alexis D; Rosario, Santano; Inaba, Kenji; Marecek, Geoffrey S

2018-04-27

Motor Vehicle Collisions (MVC) can cause high energy hip dislocations associated with serious injury profiles impacting triage. Changes in safety and regulation of restraint devices have likely lowered serious injuries from what was previously reported in the 1990s. This study aims to describe modern-day injury profile of patients with traumatic hip dislocations, with special attention to aortic injury. Retrospective review of a prospectively maintained trauma database at an urban level 1 trauma center was conducted. Patients with hip dislocation following MVC between January 2005 and December 2015 were grouped based on seatbelt use and airbag deployment. Patients with unknown restraint use were excluded. Multiple logistic regression was used to identify risk of injury profile between groups. Of 204 patients with hip dislocation after MVC, nearly 57% were unrestrained. Seatbelt alone was used in 36 (17.7%), airbag deployed in 14 (6.9%), and 38 (18.6%) with both. Gender and number of injuries were similar between groups. The most common concomitant injury was acetabular fracture (53.92%) and the abdominopelvic region was the most injured. Use of a seatbelt with airbag deployment was protective of concomitant pelvic ring injury (OR = 0.22). Airbag deployment was significantly protective of lumbar fracture (OR = 0.15) while increasing the likelihood of radial and ulnar fracture or dislocation (OR = 3.27), acetabular fracture (OR = 5.19), and abdominopelvic injury (OR = 5.07). The no restraint group had one patient (0.80%) with an intimal tear of the thoracic aorta identified on CT chest that was successfully medically managed. Hip dislocations are high energy injuries with severe associated injuries despite upgrades in restraint devices. These patients require careful examination and heightened awareness when evaluating for concomitant injuries. Copyright © 2018 Elsevier Ltd. All rights reserved.

Coating process optimization through in-line monitoring for coating weight gain using Raman spectroscopy and design of experiments.

PubMed

Kim, Byungsuk; Woo, Young-Ah

2018-05-30

In this study the authors developed a real-time Process Analytical Technology (PAT) of a coating process by applying in-line Raman spectroscopy to evaluate the coating weight gain, which is a quantitative analysis of the film coating layer. The wide area illumination (WAI) Raman probe was connected to the pan coater for real-time monitoring of changes in the weight gain of coating layers. Under the proposed in-line Raman scheme, a non-contact, non-destructive analysis was performed using WAI Raman probes with a spot size of 6 mm. The in-line Raman probe maintained a focal length of 250 mm, and a compressed air line was designed to protect the lens surface from spray droplets. The Design of Experiment (DOE) was applied to identify factors affecting the Raman spectra background of laser irradiation. The factors selected for DOE were the strength of compressed air connected to the probe, and the shielding of light by the transparent door connecting the probe to the pan coater. To develop a quantitative model, partial least squares (PLS) models as multivariate calibration were developed based on the three regions showing the specificity of TiO 2 individually or in combination. For the three single peaks (636 cm -1 , 512 cm -1 , 398 cm -1 ), least squares method (LSM) was applied to develop three univariate quantitative analysis models. One of best multivariate quantitative model having a factor of 1 gave the lowest RMSEP of 0.128, 0.129, and 0.125, respectively for prediction batches. When LSM was applied to the single peak at 636 cm -1 , the univariate quantitative model with an R 2 of 0.9863, slope of 0.5851, and y-intercept of 0.8066 had the lowest RMSEP of 0.138, 0.144, and 0.153, respectively for prediction batches. The in-line Raman spectroscopic method for the analysis of coating weight gain was verified by considering system suitability and parameters such as specificity, range, linearity, accuracy, and precision in accordance with ICH Q2 regarding method validation. The proposed in-line Raman spectroscopy can be utilized as a PAT for product quality assurance as it offers real-time monitoring of quantitative changes in coating weight gain and process end-points during the film coating process. Copyright © 2018 Elsevier B.V. All rights reserved.

The Last Interglacial History of the Antarctic Ice sheet

NASA Astrophysics Data System (ADS)

Bradley, Sarah; Siddall, Mark; Milne, Glenn A.; Masson-Delmotte, Valerie; Wolff, Eric; Hindmarsh, Richard C. A.

2014-05-01

In this paper we present a summary of the work which was conducted as part of the 'PAST4FUTURE -WP4.1: Sea Level and Ice sheets' project. The overall aim of this study was to understand the response of the Antarctic Ice sheet (AIS) to climate forcing during the Last interglacial (LIG) and its contribution to the observed higher than present sea level during this period. The study involved the application and development of a novel technique which combined East Antarctic stable isotope ice core data with the output from a Glacial Isostatic Adjustment (GIA) model [Bradley et al., 2012]. We investigated if the stable isotope ice core data are sensitive to detecting isostatically driven changes in the surface elevation driven by changes in the ice-loading history of the AIS and if so, could we address some key questions relating to the LIG history of the AIS. Although it is believed that the West Antarctic Ice sheet (WAIS) reduced in size during the LIG compared to the Holocene, major uncertainties and unknowns remain unresolved: Did the WAIS collapse? What would the contribution of such a collapse be the higher than present LIG eustatic sea level (ESL)? We will show that a simulated collapse of the WAIS does not generate a significant elevation driven signal at the EAIS LIG ice core sites, and as such, these ice core records cannot be used to assess WAIS stability over this period. However, we will present 'treasure maps' [Bradley et al., 2012] to identify regions of the AIS where results from geological studies and/or new paleoclimate data may be sensitive to detecting a WAIS collapse. These maps can act as a useful tool for the wider science community/field scientists as a guide to highlight sites suitable to constrain the evolution of the WAIS during the LIG. Studies have proposed that the surface temperature across the East Antarctic Ice Sheet (EAIS) was significantly warmer, 2-5°C during the LIG compared to present [Lang and Wolff, 2011]. These higher temperatures are estimated primarily using the difference in the δD peak in the LIG stable isotope ice core data relative to the records for the present interglacial; a feature which is referred to as the 'LIG overshoot'. Generally studies have attributed most of this signal to changes in the Antarctic climate [Masson-Delmotte et al., 2011]. However, a previously overlooked contribution is the influence of changes in surface elevation driven by changes in ice-loading history of the EAIS [Bradley et al., 2013]. We will show that introducing a relatively moderate reduction in the amount of thickening of the EAIS over the LIG, can generate a significant elevation driven δD signal at the EAIS ice core sites, and as such elevation effects can account for a significant fraction of the LIG overshoot. We will conclude that the potential contribution of this process must be considered when using the EAIS stable isotope ice core data to make estimated of the LIG surface temperature. Finally, we will provide estimates of the contribution of the AIS to both ESL and to the higher than observed relative sea level during the LIG. Bradley, S. L., M. Siddall, G. A. Milne, V. Masson-Delmotte, and E. Wolff (2012), Where might we find evidence of a Last Interglacial West Antarctic Ice Sheet collapse in Antarctic ice core records?, Global and Planetary Change, 88-89(0), 64-75. Bradley, S. L., M. Siddall, G. A. Milne, V. Masson-Delmotte, and E. Wolff (2013), Combining ice core records and ice sheet models to explore the evolution of the East Antarctic Ice sheet during the Last Interglacial period, Global and Planetary Change, 100, 278-290. Lang, N., and E. W. Wolff (2011), Interglacial and glacial variability from the last 800 ka in marine, ice and terrestrial archives, Clim. Past., 7(2), 361-380. Masson-Delmotte, V., et al. (2011), A comparison of the present and last interglacial periods in six Antarctic ice cores, Clim. Past., 7(2), 397-423.

A Split in the Verbal Comprehension Factor in WAIS and WISC-R Profiles.

ERIC Educational Resources Information Center

McGee, Shanna; Brown, Coke

1984-01-01

Examined the pattern of verbal subscale scores on the Wechsler Adult Intelligence Scale and Wechsler Intelligence Scale for Children-Revised given to college students (N=129) and elementary students (N=383). Results showed a triangle pattern (Comprehension scores higher than both Vocabulary and Information) that begins to appear at the…

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Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-29

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Verbal and Performance IQ for Discrimination Among Psychiatric Diagnostic Groups

ERIC Educational Resources Information Center

Loro, Bert; Woodward, J. Arthur

1976-01-01

In view of the practical and theoretical importance of the issues involved, the current research was undertaken to investigate the diagnostic relevance of WAIS Verbal and Performance IQ in a large sample of psychiatric patients that included a variety of functional diagnostic groups as well as groups of mentally deficient and organic brain…

Social Perception and WAIS-IV Performance in Adolescents and Adults Diagnosed with Asperger's Syndrome and Autism

ERIC Educational Resources Information Center

Holdnack, James; Goldstein, Gerald; Drozdick, Lisa

2011-01-01

Previous research using the Wechsler scales has identified areas of cognitive weaknesses in children, adolescents, and adults diagnosed with Autism or Asperger's syndrome. The current study evaluates cognitive functioning in adolescents and adults diagnosed with Autism or Asperger's syndrome using the Wechsler Adult Intelligence Scale-Fourth…

Normative Study of Wideband Acoustic Immittance Measures in Newborn Infants

ERIC Educational Resources Information Center

Aithal, Sreedevi; Kei, Joseph; Aithal, Venkatesh; Manuel, Alehandrea; Myers, Joshua; Driscoll, Carlie; Khan, Asaduzzaman

2017-01-01

Objective: The purpose of this study was to describe normative aspects of wideband acoustic immittance (WAI) measures obtained from healthy White neonates. Method: In this cross-sectional study, wideband absorbance (WBA), admittance magnitude, and admittance phase were measured under ambient pressure condition in 326 ears from 203 neonates (M age…

On the Nets. Comparing Web Browsers: Mosaic, Cello, Netscape, WinWeb and InternetWorks Life.

ERIC Educational Resources Information Center

Notess, Greg R.

1995-01-01

World Wide Web browsers are compared by speed, setup, hypertext transport protocol (HTTP) handling, management of file transfer protocol (FTP), telnet, gopher, and wide area information server (WAIS); bookmark options; and communication functions. Netscape has the most features, the fastest retrieval, sophisticated bookmark capabilities. (JMV)

Control and the Aged: Environmental or Personality Factors.

ERIC Educational Resources Information Center

Tiffany, Phyllis G.; Dey, Kay

Control over self, lifestyle, and environment is a major factor in how one ages. To investigate how age acts as an environmental force in affecting perceptions of control, 45 adults, aged 60-80, from western Kansas were administered the Wechsler Adult Intelligence Scale (WAIS), the Tiffany Experienced Control Scales (ECS), the Minnesota…

Ko Wai Au? Who Am I? Examining the Multiple Identities of Maori Youth

ERIC Educational Resources Information Center

Faircloth, Susan C.; Hynds, Anne; Jacob, Helen; Green, Clint; Thompson, Patrick

2016-01-01

In this paper, we present preliminary findings from a unique collaborative research project involving six Deaf Maori rangatahi (youth) in Tamaki Makaurau (Auckland), Aotearoa New Zealand. This study utilized kaupapa whanau (research family) protocols, established in consultation with two cultural advisory groups within New Zealand and the young…

GPO Gate: University of California, San Diego's New Gateway to Electronic Government Information.

ERIC Educational Resources Information Center

Cruse, Patricia; Jahns, Cynthia

1996-01-01

Describes the development of a new interface called GPO Gate for accessing the Government Printing Office (GPO) WAIS (wide area information server) databases, GPO Access. Highlights include development and use of GPO Gate at the University of California, San Diego, and implications for public service. (Author/LRW)

Measuring Components of Intelligence: Mission Impossible?

ERIC Educational Resources Information Center

Gregoire, Jacques

2013-01-01

The two studies conducted by Weiss, Keith, Zhu, and Chen in 2013 on the Wechsler Adult Intelligence Scale (WAIS-IV) and the Wechsler Intelligence Scale for Children (WISC-IV), respectively, provide strong evidence for the validity of a four-factor solution corresponding to the current hierarchical model of both scales. These analyses support the…

Two New Empirically Derived Reasons To Use the Assessment of Basic Learning Abilities.

ERIC Educational Resources Information Center

Richards, David F.; Williams, W. Larry; Follette, William C.

2002-01-01

Scores on the Assessment of Basic Learning Abilities (ABLA), Vineland Adaptive Behavior Scales, and the Wechsler Intelligences Scale-Revised (WAIS-R) were obtained for 30 adults with mental retardation. Correlations between the Vineland domains and ABLA were all significant. No participants performing below ABLA Level 6 were testable on the…

Cognitive Tasks as Predictors of Behavioral Competencies in the Aged.

ERIC Educational Resources Information Center

Cyr, J.; Stones, M. J.

This paper discusses the quantitative and qualitative aspects of the relationship between cognitive abilities and behavioral competencies in elderly institutional residents. The former was assessed by an array of five cognitive measures: two Piagetian tasks, Set Test, WAIS Vocabulary and Digit Span subtests, and the WMS Associate Learning subtest;…

The Flynn Effect in South Africa

ERIC Educational Resources Information Center

te Nijenhuis, Jan; Murphy, Raegan; van Eeden, Rene

2011-01-01

This is a study of secular score gains in South Africa. The findings are based on representative samples from datasets utilized in norm studies of popular mainstream intelligence batteries such as the WAIS as well as widely used test batteries which were locally developed and normed in South Africa. Flynn effects were computed in three ways.…

Over- and Undercontrolled Referral Problems among Children and Adolescents from Thailand and the United States: The "Wat" and "Wai" of Cultural Differences.

ERIC Educational Resources Information Center

Weisz, John R.; And Others

1987-01-01

Compared Thailand to United States in regard to children's psychological problems and corresponding clinic referral patterns. Overcontrolled problems (somaticizing, fearfulness, nervous movements, worrying) were reported more often for Thai than for American youth. Undercontrolled problems (disobedience, fighting, lying, arguing) were reported…

The Luria-Nebraska Neuropsychological Battery and the WAIS-R in Assessment of Adults with Specific Learning Disabilities.

ERIC Educational Resources Information Center

Katz, Lynda; Goldstein, Gerald

1993-01-01

Compared intellectual (Wechsler Adult Intelligence Scale for Adults-Revised) and neuropsychological (Luria-Nebraska Neuropsychological Battery) assessment as valid methods of identifying learning disabilities in adults. Findings from 155 subjects revealed that both instruments were able to distinguish adults with and without learning disabilities.…

High geothermal heat flux measured below the West Antarctic Ice Sheet

PubMed Central

Fisher, Andrew T.; Mankoff, Kenneth D.; Tulaczyk, Slawek M.; Tyler, Scott W.; Foley, Neil

2015-01-01

The geothermal heat flux is a critical thermal boundary condition that influences the melting, flow, and mass balance of ice sheets, but measurements of this parameter are difficult to make in ice-covered regions. We report the first direct measurement of geothermal heat flux into the base of the West Antarctic Ice Sheet (WAIS), below Subglacial Lake Whillans, determined from the thermal gradient and the thermal conductivity of sediment under the lake. The heat flux at this site is 285 ± 80 mW/m2, significantly higher than the continental and regional averages estimated for this site using regional geophysical and glaciological models. Independent temperature measurements in the ice indicate an upward heat flux through the WAIS of 105 ± 13 mW/m2. The difference between these heat flux values could contribute to basal melting and/or be advected from Subglacial Lake Whillans by flowing water. The high geothermal heat flux may help to explain why ice streams and subglacial lakes are so abundant and dynamic in this region. PMID:26601210

On the pattern of WAIS retreat in eastern Ross Sea based on a regional synthesis of new geophysical and geological data acquired during NBP1502

NASA Astrophysics Data System (ADS)

McGlannan, A. J.; Bart, P. J.; Anderson, J. B.

2016-02-01

New multibeam and seismic data acquired during NBP1502 reveal that a series of backstepping grounding zone wedges (GZWs) were constructed on the middle shelf as the West Antarctic Ice Sheet (WAIS) retreated from the Whales Deep paleo-ice stream trough. The geomorphological information provided by these geophysical data were used to acquire a regional grid of jumbo-piston and kasten cores. Here, we present our regional synthesis of the new geophysical and geological data. The distributions of upcore transitions from diamict to sub-ice-shelf facies on the outer-most shelf demonstrate that as the grounded ice retreated in four discrete backsteps, the calving front remained in the vicinity of the shelf edge, approximately 50 kilometers to the north. In contrast, the upcore transition at the fourth backstep shows GZW diamict directly overlain by open-marine facies. We interpret this to indicate that a major retreat of both grounded and floating ice was associated with the termination of the middle-shelf grounding event. The minimum retreat distance was greater than 100 kilometers.

Cognitive status and profile validity on the Personality Assessment Inventory (PAI) in offenders with serious mental illness.

PubMed

Matlasz, Tatiana M; Brylski, Jamie L; Leidenfrost, Corey M; Scalco, Matt; Sinclair, Samuel J; Schoelerman, Ronald M; Tsang, Valerie; Antonius, Daniel

Cognitive impairment among seriously mentally ill offenders has implications for legal matters (e.g., competency to stand trial), as well as clinical treatment and care. Thus, being able to identify potential cognitive concerns early in the adjudication process can be important when deciding on further interventions. In this study, we examined the validity scales of the Personality Assessment Inventory (PAI), scores on the Wechsler Adult Intelligence Scale-IV (WAIS-IV), and competency findings in male inmates (n=61) diagnosed with a serious mental illness. Lower scores on the WAIS-IV significantly (p=0.001) predicted invalid, versus valid, PAI profiles, with working memory impairment being the most significant (p=0.004) predictor of an invalid profile. Ancillary analyses on a smaller sample (n=18) indicate that those with invalid PAI profiles were more likely to be deemed legally incompetent (p=0.03). These findings suggest that the PAI validity scales may be informative in detecting cognitive concerns and help clinicians make determinations about competency restoration and treatment. Copyright © 2016 Elsevier Ltd. All rights reserved.

Association between the epidermal growth factor gene and intelligence in major depression patients.

PubMed

Tian, Wen-min; Zhang, Ke-ran; Zhang, Juan; Shen, Yan; Xu, Qi

2010-06-01

To study the association between the epidermal growth factor (EGF) gene and intelligence in patients with major depression. Intelligence measurement using Wechsler Adult Intelligence Scale (WAIS) was performed on 120 unrelated patients with major depression and 46 control subjects. Blood was collected from all subjects for extraction of genomic DNA. Four single nucleotide polymorphisms (SNPs) in the EGF gene were genotyped using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI- TOF-MS). Mean scores of both score lang and score task, two subtests in WAIS, differed significantly between major depression patients and controls (P<0.0001). Quantitative trait analysis showed that the genotype of rs2250724 was closely associated with score lang and score task in major depression patients. The associations were still significant after 10 000 permutations. Although preliminary, our results provide evidence for association between the EGF gene and intelligence in patients with major depression. Genetic variation in the EGF gene may increase the susceptibility of major depression.

Fund of Information is More Strongly Associated with Neuropsychological Functioning Than Education in Older Spanish Adults.

PubMed

Correia, Rut; Nieto, Antonieta; Ferreira, Daniel; Sabucedo, María; Barroso, Jose

2015-06-01

Educational influence on cognitive performance has been extensively agreed in Neuropsychology. Nonetheless, recent studies highlighted the need of better measurements to assess benefit from the schooling experience in order to further understand schooling influence on cognition. The WAIS-III Information subtest is proposed here to measure this influence at old age. Ninety-five older adults were divided according to their educational attainment and their Information subtest score, and completed extensive neuropsychological assessment. Performance on the Information subtest had a significant effect on all same cognitive functions as educational attainment, but also on additional domains. Moreover, cognitive performance on several tasks can be classified in three levels as a function of Information score. The WAIS-III Information subtest could be of special interest as a measurement of the benefit from educational experience not only to study cognition in Spanish older populations but also heterogeneous samples in terms of educational experiences and environments. © The Author 2015. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Metric and structural equivalence of core cognitive abilities measured with the Wechsler Adult Intelligence Scale-III in the United States and Australia.

PubMed

Bowden, Stephen C; Lissner, Dianne; McCarthy, Kerri A L; Weiss, Lawrence G; Holdnack, James A

2007-10-01

Equivalence of the psychological model underlying Wechsler Adult Intelligence Scale-Third Edition (WAIS-III) scores obtained in the United States and Australia was examined in this study. Examination of metric invariance involves testing the hypothesis that all components of the measurement model relating observed scores to latent variables are numerically equal in different samples. The assumption of metric invariance is necessary for interpretation of scores derived from research studies that seek to generalize patterns of convergent and divergent validity and patterns of deficit or disability. An Australian community volunteer sample was compared to the US standardization data. A pattern of strict metric invariance was observed across samples. In addition, when the effects of different demographic characteristics of the US and Australian samples were included, structural parameters reflecting values of the latent cognitive variables were found not to differ. These results provide important evidence for the equivalence of measurement of core cognitive abilities with the WAIS-III and suggest that latent cognitive abilities in the US and Australia do not differ.

Magnetic Resonance of Pelvic and Gastrointestinal Emergencies.

PubMed

Wongwaisayawan, Sirote; Kaewlai, Rathachai; Dattwyler, Matthew; Abujudeh, Hani H; Singh, Ajay K

2016-05-01

Magnetic resonance (MR) imaging is gaining increased acceptance in the emergency setting despite the continued dominance of computed tomography. MR has the advantages of more precise tissue characterization, superior soft tissue contrast, and a lack of ionizing radiation. Traditional barriers to emergent MR are being overcome by streamlined imaging protocols and newer rapid-acquisition sequences. As the utilization of MR imaging in the emergency department increases, a strong working knowledge of the MR appearance of the most commonly encountered abdominopelvic pathologies is essential. In this article, MR imaging protocols and findings of acute pelvic, scrotal, and gastrointestinal pathologies are discussed. Copyright © 2016 Elsevier Inc. All rights reserved.

Iterative Reconstruction Techniques in Abdominopelvic CT: Technical Concepts and Clinical Implementation.

PubMed

Patino, Manuel; Fuentes, Jorge M; Singh, Sarabjeet; Hahn, Peter F; Sahani, Dushyant V

2015-07-01

This article discusses the clinical challenge of low-radiation-dose examinations, the commonly used approaches for dose optimization, and their effect on image quality. We emphasize practical aspects of the different iterative reconstruction techniques, along with their benefits, pitfalls, and clinical implementation. The widespread use of CT has raised concerns about potential radiation risks, motivating diverse strategies to reduce the radiation dose associated with CT. CT manufacturers have developed alternative reconstruction algorithms intended to improve image quality on dose-optimized CT studies, mainly through noise and artifact reduction. Iterative reconstruction techniques take unique approaches to noise reduction and provide distinct strength levels or settings.

Computed Tomography of the Head and Neck Region for Tumor Staging-Comparison of Dual-Source, Dual-Energy and Low-Kilovolt, Single-Energy Acquisitions.

PubMed

May, Matthias Stefan; Bruegel, Joscha; Brand, Michael; Wiesmueller, Marco; Krauss, Bernhard; Allmendinger, Thomas; Uder, Michael; Wuest, Wolfgang

2017-09-01

The aim of this study was to intra-individually compare the image quality obtained by dual-source, dual-energy (DSDE) computed tomography (CT) examinations and different virtual monoenergetic reconstructions to a low single-energy (SE) scan. Third-generation DSDE-CT was performed in 49 patients with histologically proven malignant disease of the head and neck region. Weighted average images (WAIs) and virtual monoenergetic images (VMIs) for low (40 and 60 keV) and high (120 and 190 keV) energies were reconstructed. A second scan aligned to the jaw, covering the oral cavity, was performed for every patient to reduce artifacts caused by dental hardware using a SE-CT protocol with 70-kV tube voltages and matching radiation dose settings. Objective image quality was evaluated by calculating contrast-to-noise ratios. Subjective image quality was evaluated by experienced radiologists. Highest contrast-to-noise ratios for vessel and tumor attenuation were obtained in 40-keV VMI (all P < 0.05). Comparable objective results were found in 60-keV VMI, WAI, and the 70-kV SE examinations. Overall subjective image quality was also highest for 40-keV, but differences to 60-keV VMI, WAI, and 70-kV SE were nonsignificant (all P > 0.05). High kiloelectron volt VMIs reduce metal artifacts with only limited diagnostic impact because of insufficiency in case of severe dental hardware. CTDIvol did not differ significantly between both examination protocols (DSDE: 18.6 mGy; 70-kV SE: 19.4 mGy; P = 0.10). High overall image quality for tumor delineation in head and neck imaging were obtained with 40-keV VMI. However, 70-kV SE examinations are an alternative and modified projections aligned to the jaw are recommended in case of severe artifacts caused by dental hardware.

Obliquity-paced Pliocene West Antarctic ice sheet oscillations

USGS Publications Warehouse

Naish, T.; Powell, R.; Levy, R.; Wilson, G.; Scherer, R.; Talarico, F.; Krissek, L.; Niessen, F.; Pompilio, M.; Wilson, T.; Carter, L.; DeConto, R.; Huybers, P.; McKay, R.; Pollard, D.; Ross, J.; Winter, D.; Barrett, P.; Browne, G.; Cody, R.; Cowan, E.; Crampton, J.; Dunbar, G.; Dunbar, N.; Florindo, F.; Gebhardt, C.; Graham, I.; Hannah, M.; Hansaraj, D.; Harwood, D.; Helling, D.; Henrys, S.; Hinnov, L.; Kuhn, G.; Kyle, P.; Laufer, A.; Maffioli, P.; Magens, D.; Mandernack, K.; McIntosh, W.; Millan, C.; Morin, R.; Ohneiser, C.; Paulsen, T.; Persico, D.; Raine, I.; Reed, J.; Riesselman, C.; Sagnotti, L.; Schmitt, D.; Sjunneskog, C.; Strong, P.; Taviani, M.; Vogel, S.; Wilch, T.; Williams, T.

2009-01-01

Thirty years after oxygen isotope records from microfossils deposited in ocean sediments confirmed the hypothesis that variations in the Earth's orbital geometry control the ice ages1, fundamental questions remain over the response of the Antarctic ice sheets to orbital cycles2. Furthermore, an understanding of the behaviour of the marine-based West Antarctic ice sheet (WAIS) during the 'warmer-than-present' early-Pliocene epoch (5–3 Myr ago) is needed to better constrain the possible range of ice-sheet behaviour in the context of future global warming3. Here we present a marine glacial record from the upper 600 m of the AND-1B sediment core recovered from beneath the northwest part of the Ross ice shelf by the ANDRILL programme and demonstrate well-dated, 40-kyr cyclic variations in ice-sheet extent linked to cycles in insolation influenced by changes in the Earth's axial tilt (obliquity) during the Pliocene. Our data provide direct evidence for orbitally induced oscillations in the WAIS, which periodically collapsed, resulting in a switch from grounded ice, or ice shelves, to open waters in the Ross embayment when planetary temperatures were up to 3 °C warmer than today4 and atmospheric CO2 concentration was as high as 400 p.p.m.v. (refs 5, 6). The evidence is consistent with a new ice-sheet/ice-shelf model7 that simulates fluctuations in Antarctic ice volume of up to +7 m in equivalent sea level associated with the loss of the WAIS and up to +3 m in equivalent sea level from the East Antarctic ice sheet, in response to ocean-induced melting paced by obliquity. During interglacial times, diatomaceous sediments indicate high surface-water productivity, minimal summer sea ice and air temperatures above freezing, suggesting an additional influence of surface melt8 under conditions of elevated CO2.

Obliquity-paced Pliocene West Antarctic ice sheet oscillations.

PubMed

Naish, T; Powell, R; Levy, R; Wilson, G; Scherer, R; Talarico, F; Krissek, L; Niessen, F; Pompilio, M; Wilson, T; Carter, L; DeConto, R; Huybers, P; McKay, R; Pollard, D; Ross, J; Winter, D; Barrett, P; Browne, G; Cody, R; Cowan, E; Crampton, J; Dunbar, G; Dunbar, N; Florindo, F; Gebhardt, C; Graham, I; Hannah, M; Hansaraj, D; Harwood, D; Helling, D; Henrys, S; Hinnov, L; Kuhn, G; Kyle, P; Läufer, A; Maffioli, P; Magens, D; Mandernack, K; McIntosh, W; Millan, C; Morin, R; Ohneiser, C; Paulsen, T; Persico, D; Raine, I; Reed, J; Riesselman, C; Sagnotti, L; Schmitt, D; Sjunneskog, C; Strong, P; Taviani, M; Vogel, S; Wilch, T; Williams, T

2009-03-19

Thirty years after oxygen isotope records from microfossils deposited in ocean sediments confirmed the hypothesis that variations in the Earth's orbital geometry control the ice ages, fundamental questions remain over the response of the Antarctic ice sheets to orbital cycles. Furthermore, an understanding of the behaviour of the marine-based West Antarctic ice sheet (WAIS) during the 'warmer-than-present' early-Pliocene epoch ( approximately 5-3 Myr ago) is needed to better constrain the possible range of ice-sheet behaviour in the context of future global warming. Here we present a marine glacial record from the upper 600 m of the AND-1B sediment core recovered from beneath the northwest part of the Ross ice shelf by the ANDRILL programme and demonstrate well-dated, approximately 40-kyr cyclic variations in ice-sheet extent linked to cycles in insolation influenced by changes in the Earth's axial tilt (obliquity) during the Pliocene. Our data provide direct evidence for orbitally induced oscillations in the WAIS, which periodically collapsed, resulting in a switch from grounded ice, or ice shelves, to open waters in the Ross embayment when planetary temperatures were up to approximately 3 degrees C warmer than today and atmospheric CO(2) concentration was as high as approximately 400 p.p.m.v. (refs 5, 6). The evidence is consistent with a new ice-sheet/ice-shelf model that simulates fluctuations in Antarctic ice volume of up to +7 m in equivalent sea level associated with the loss of the WAIS and up to +3 m in equivalent sea level from the East Antarctic ice sheet, in response to ocean-induced melting paced by obliquity. During interglacial times, diatomaceous sediments indicate high surface-water productivity, minimal summer sea ice and air temperatures above freezing, suggesting an additional influence of surface melt under conditions of elevated CO(2).

Modelling West Antarctic ice sheet growth and collapse through the past five million years.

PubMed

Pollard, David; DeConto, Robert M

2009-03-19

The West Antarctic ice sheet (WAIS), with ice volume equivalent to approximately 5 m of sea level, has long been considered capable of past and future catastrophic collapse. Today, the ice sheet is fringed by vulnerable floating ice shelves that buttress the fast flow of inland ice streams. Grounding lines are several hundred metres below sea level and the bed deepens upstream, raising the prospect of runaway retreat. Projections of future WAIS behaviour have been hampered by limited understanding of past variations and their underlying forcing mechanisms. Its variation since the Last Glacial Maximum is best known, with grounding lines advancing to the continental-shelf edges around approximately 15 kyr ago before retreating to near-modern locations by approximately 3 kyr ago. Prior collapses during the warmth of the early Pliocene epoch and some Pleistocene interglacials have been suggested indirectly from records of sea level and deep-sea-core isotopes, and by the discovery of open-ocean diatoms in subglacial sediments. Until now, however, little direct evidence of such behaviour has been available. Here we use a combined ice sheet/ice shelf model capable of high-resolution nesting with a new treatment of grounding-line dynamics and ice-shelf buttressing to simulate Antarctic ice sheet variations over the past five million years. Modelled WAIS variations range from full glacial extents with grounding lines near the continental shelf break, intermediate states similar to modern, and brief but dramatic retreats, leaving only small, isolated ice caps on West Antarctic islands. Transitions between glacial, intermediate and collapsed states are relatively rapid, taking one to several thousand years. Our simulation is in good agreement with a new sediment record (ANDRILL AND-1B) recovered from the western Ross Sea, indicating a long-term trend from more frequently collapsed to more glaciated states, dominant 40-kyr cyclicity in the Pliocene, and major retreats at marine isotope stage 31 ( approximately 1.07 Myr ago) and other super-interglacials.

The Facilitative Effect of Transcranial Direct Current Stimulation on Visuospatial Working Memory in Patients with Diabetic Polyneuropathy: A Pre–post Sham-Controlled Study

PubMed Central

Wu, Yi-Jen; Tseng, Philip; Huang, Han-Wei; Hu, Jon-Fan; Juan, Chi-Hung; Hsu, Kuei-Sen; Lin, Chou-Ching

2016-01-01

Diabetes mellitus can lead to diabetic polyneuropathy (DPN) and cognitive deficits that manifest as peripheral and central neuropathy, respectively. In this study we investigated the relationship between visuospatial working memory (VSWM) capacity and DPN severity, and attempted to improve VSWM in DPN patients via the use of transcranial direct current stimulation (tDCS). Sixteen DPN patients and 16 age- and education-matched healthy control subjects received Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) and Montreal Cognitive Assessment (MOCA) for baseline cognitive assessment. A forward- and backward-recall computerized Corsi block tapping task (CBT), both with and without a concurrent motor interference task was used to measure VSWM capacity. Each DPN patient underwent a pre-treatment CBT, followed by tDCS or sham treatment, then a post-treatment CBT on two separate days. We found that although patients with severe DPN (Dyck’s grade 2a or 2b) showed comparable general intelligence scores on WAIS-IV as their age- and education-matched healthy counterparts, they nonetheless showed mild cognitive impairment (MCI) on MOCA and working memory deficit on digit-span test of WAIS-IV. Furthermore, patients’ peripheral nerve conduction velocity (NCV) was positively correlated with their VSWM span in the most difficult CBT condition that involved backward-recall with motor interference such that patients with worse NCV also had lower VSWM span. Most importantly, anodal tDCS over the right DLPFC was able to improve low-performing patients’ VSWM span to be on par with the high-performers, thereby eliminating the correlation between NCV and VSWM. In summary, these findings suggest that (1) MCI and severe peripheral neuropathy can coexist with unequal severity in diabetic patients, (2) the positive correlation of VSWM and NCV suggests a link between peripheral and central neuropathies, and (3) anodal tDCS over the right DLPFC can improve DPN patients’ VSWM, particularly for the low-performing patients. PMID:27733822

Long-term impact of subthalamic stimulation on cognitive function in patients with advanced Parkinson's disease.

PubMed

Acera, M; Molano, A; Tijero, B; Bilbao, G; Lambarri, I; Villoria, R; Somme, J; Ruiz de Gopegui, E; Gabilondo, I; Gomez-Esteban, J C

2017-07-13

The aim of this study was to evaluate the effects of deep brain stimulation of the subthalamic nucleus (DBS-SN) on cognitive function in patients with Parkinson's disease (PD) 5 years after surgery. We conducted a prospective study including 50 patients with PD who underwent DBS-SN (62.5% were men; mean age of 62.2±8.2 years; mean progression time of 14.1±6.3 years). All patients were assessed before the procedure and at one year after surgery; 40 patients were further followed up until the 5-year mark. Follow-up assessments included the following neuropsychological tests: Mini-Mental State Examination (MMSE), Mattis Dementia Rating Scale (MDRS), letter-number sequencing of the WAIS-III (WAIS-III-LN), clock-drawing test, Rey auditory verbal learning test (RAVLT), Benton Visual Retention Test (BVRT), Judgment of Line Orientation (JLO) test, FAS Phonemic Verbal Fluency Test, Stroop test, and the Montgomery-Asberg Depression Rating Scale (MADRS). Patients were found to score lower on the MMSE (-0.89%), clock-drawing test (-2.61%), MDRS (-1.72%), and especially phonemic (-13.28%) and sematic verbal fluency tests (-12.40%) at one year after surgery. Delayed recall on the RAVLT worsened one year after the procedure (-10.12%). At 5 years, impairment affected mainly verbal fluency; scores decreased an additional 16.10% and 16.60% in semantic and phonemic verbal fluency, respectively. Moderate decreases were observed in immediate recall (-16.87%), WAIS-III-LN (-16.67%), and JLO test (-11.56%). In our sample, DBS-SN did not result in global cognitive impairment 5 years after surgery. Verbal function was found to be significantly impaired one year after the procedure. Impaired learning and visuospatial function may be attributed to degeneration associated with PD. Copyright © 2017 Sociedad Española de Neurología. Publicado por Elsevier España, S.L.U. All rights reserved.

Work ability of health care shift workers: What matters?

PubMed

Fischer, Frida Marina; Borges, Flavio Notarnicola da Silva; Rotenberg, Lucia; Latorre, Maria do Rosario Dias de Oliveira; Soares, Nilson Santos; Rosa, Patricia Lima Ferreira Santa; Teixeira, Liliane Reis; Nagai, Roberta; Steluti, Josiane; Landsbergis, Paul

2006-01-01

This paper aims at identifying variables associated with inadequate work ability among nursing personnel at a public hospital, considering factors related to socio-demographic, lifestyles, working conditions, and health outcomes. A cross-sectional study was conducted in a university hospital in São Paulo, Brazil, as part of a larger research study on tolerance to 12 h night work. Nursing staff included registered nurses, nurse technicians, and nurse aides; in total, there were 996 healthcare workers (878 female; 118 male) at the time of the study. Some 696 workers (69.9%) of the population agreed to participate. Data collection (October 2004-July 2005) was based on a comprehensive questionnaire about living and working conditions (including incivility at work, work demands, work control, and support), mental and physical health symptoms (fatigue and sleep problems), and work ability. This report presents analyses of the adapted Brazilian version of the Work Ability Index (WAI) and associated variables. The study population worked one of the following shift schedules at this hospital: 12 h nights followed by 36 h off or 9 h or 6 h day (morning or afternoon) shifts. The mean age of the respondents was 34.9 (S.D.+/-10.4) years of age; 31.5% of the participants held two jobs. Statistical analyses using a hierarchical multiple logistic regression model were performed to evaluate the factors associated with inadequate (moderate and low scores) of the WAI. The significantly associated factors were socio-demographic (income responsibility, sole breadwinner, raising kids, age group), working conditions (thermal discomfort, organization of the workplace, and verbal abuse), and health outcomes (high body mass index, obesity, sleep problems, and fatigue). In spite of limitations of the study design, results indicate that the nursing profession is associated with stressful working conditions, contributing to inadequate WAI. This is in addition to bad living conditions and precarious work. Intervention measures, either at the workplace or at individual levels, are necessary to prevent a decrease in work ability, even in this quite young working population.

Shallow-source aeromagnetic anomalies observed over the West Antarctic Ice Sheet compared with coincident bed topography from radar ice sounding - New evidence for glacial "removal" of subglacially erupted late Cenozoic rift-related volcanic edifices

USGS Publications Warehouse

Behrendt, John C.; Blankenship, D.D.; Morse, D.L.; Bell, R.E.

2004-01-01

Aeromagnetic and radar ice sounding results from the 1991-1997 Central West Antarctica (CWA) aerogeophysical survey over part of the West Antarctic Ice Sheet (WAIS) and subglacial area of the volcanically active West Antarctic rift system have enabled detailed examination of specific anomaly sources. These anomalies, previously interpreted as caused by late Cenozoic subglacial volcanic centers, are compared to newly available glacial bed-elevation data from the radar ice sounding compilation of the entire area of the aeromagnetic survey to test this hypothesis in detail. We examined about 1000 shallow-source magnetic anomalies for bedrock topographic expression. Using very conservative criteria, we found over 400 specific anomalies which correlate with bed topography directly beneath each anomaly. We interpret these anomalies as indicative of the relative abundance of volcanic anomalies having shallow magnetic sources. Of course, deeper source magnetic anomalies are present, but these have longer wavelengths, lower gradients and mostly lower amplitudes from those caused by the highly magnetic late Cenozoic volcanic centers. The great bulk of these >400 (40-1200-nT) anomaly sources at the base of the ice have low bed relief (60-600 m, with about 80%10 million years ago. Eighteen of the anomalies examined, about half concentrated in the area of the WAIS divide, have high-topographic expression (as great as 400 m above sea level) and high bed relief (up to 1500 m). All of these high-topography anomaly sources at the base of the ice would isostatically rebound to elevations above sea level were the ice removed. We interpret these 18 anomaly sources as evidence of subaerial eruption of volcanoes whose topography was protected from erosion by competent volcanic flows similar to prominent volcanic peaks that are exposed above the surface of the WAIS. Further, we infer these volcanoes as possibly erupted at a time when the WAIS was absent. In contrast, at the other extreme, there are a number of shallow-source, volcanic appearing magnetic anomalies overlying the very smooth bed topography in the survey area beneath Ice Stream D (Bindshadler Ice Stream); the glacial bed probably comprises a very thin layer of unconsolidated sediments (till). Probably, the volcanic edifices here were removed at a more rapid rate because of fast glacial flow. A few of the very shallow-source "volcanic" anomalies overlie the ice shelf just downstream of the grounding line of Ice Stream D, suggesting a causal relationship, if the volcanism is recent. ?? 2004 Elsevier B.V. All rights reserved.

Interaction of Tacrine at M1 and M2 Cholinoceptors in Guinea Pig Brain

DTIC Science & Technology

1993-01-01

NUMBERS cholinoceptors in Guinea Pig Brain 6 AUTHOR Maria Szilagyi and Wai-Man Lau 7 FOAMING ORG KES/eADORENESS DEFENCE SCIENCE AND S PEFORMING Wa REPO...rat heart muscarinic receptors using 3 Freeman SE, Lau W-M, Szilagyi M: M2 muscarinic receptors. Neurosci the new M2 selective antagonist Blockade of

76 FR 12940 - Honey from the People's Republic of China: Partial Rescission of Antidumping Duty Administrative...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-09

... Wai Yuan Bee Products Co., Ltd.; Chengdu Stone Dynasty Art Stone; Damco China Limited Qingdao Branch; Eurasia Bee's Products Co., Ltd.; Feidong Foreign Trade Co., Ltd.; Fresh Honey Co., Ltd. (formerly Mgl....; Hengjide Healthy Products Co. Ltd.; Hubei Yusun Co., Ltd.; Inner Mongolia Altin Bee-Keeping; Inner Mongolia...

Wechsler Adult Intelligence Scale-Third Edition Short Form for Index and IQ Scores in a Psychiatric Population

ERIC Educational Resources Information Center

Christensen, Bruce K.; Girard, Todd A.; Bagby, R. Michael

2007-01-01

An eight-subtest short form (SF8) of the Wechsler Adult Intelligence Scale, Third Edition (WAIS-III), maintaining equal representation of each index factor, was developed for use with psychiatric populations. Data were collected from a mixed inpatient/outpatient sample (99 men and 101 women) referred for neuropsychological assessment. Psychometric…

The Swedish WAIS-R Factor Structure and Cognitive Profiles for Adults with Dyslexia.

ERIC Educational Resources Information Center

Alm, Jan; Kaufman, Alan S.

2002-01-01

Factor analysis of the Swedish version of the Wechsler Adult Intelligence Scale-Revised on 88 adults with dyslexia showed a three-factor structure: a verbal comprehension (VC) factor, a perceptual organization (PO) factor, and a freedom from distractibility (FD) factor. The PO factor had the highest scores and the FD the lowest. (Contains…

Utilizing WAIS Scores to Determine Foreign Language Pathways and Learning Assistance for Students with Learning Disabilities

ERIC Educational Resources Information Center

Trammell, Jack

2016-01-01

Foreign language (FL) requirements at postsecondary institutions remain a major hurdle for many students with learning disabilities (LD) as well as a significant portion of students without diagnosed LD. Many institutions have developed foreign language substitution (FLS) policies that allow students with LD to take alternate paths to meet the…

Effects of Consecutive Wideband Tympanometry Trials on Energy Absorbance Measures of the Middle Ear

ERIC Educational Resources Information Center

Burdiek, Laina M.; Sun, Xiao-Ming

2014-01-01

Purpose: Wideband acoustic immittance (WAI) is a new technique for assessing middle ear transfer function. It includes energy absorbance (EA) measures and can be acquired with the ear canal pressure varied, known as "wideband tympanometry" (WBTymp). The authors of this study aimed to investigate effects of consecutive WBTymp testing on…

A Nationwide Population-Based Approach to Study Health-Related and Psychosocial Aspects of Neurofibromatosis Type 1

DTIC Science & Technology

2016-07-31

the relatively narrow focus on Wechsler’s IQ test (WAIS-IV) – a test chosen primarily due to budget constraints. Thus, to meet the requests from the...consultants allows us to re-allocate financial resources to address the limitations of our study 7 raised by the reviewers. Jens Richardt Møllegaard

West Antarctic Ice Sheet Initiative. Volume 2: Discipline Reviews

NASA Technical Reports Server (NTRS)

Bindschadler, Robert A. (Editor)

1991-01-01

Seven discipline review papers are presented on the state of the knowledge of West Antarctica and opinions on how that knowledge must be increased to predict the future behavior of this ice sheet and to assess its potential to collapse, rapidly raising the global sea level. These are the goals of the West Antarctic Ice Sheet Initiative (WAIS).

The Relationship between Age and IQ in Adults with Williams Syndrome

ERIC Educational Resources Information Center

Searcy, Yvonne M.; Lincoln, Alan J.; Rose, Fredric E.; Klima, Edward S.; Bavar, Nasim; Korenberg, Julie R.

2004-01-01

The relationship between age and IQ was evaluated in a cross-sectional sample of 80 individuals with Williams syndrome (17 to 52 years). The relationship between age and WAIS-R subtest scores was such that increases and decreases in raw scores occurred at a rate sufficient to maintain stability of age-corrected scaled scores, indicating a…

Adult Dyslexia and Attention Deficit Disorder in Finland--Project DyAdd: WAIS-III Cognitive Profiles

ERIC Educational Resources Information Center

Laasonen, Marja; Leppamaki, Sami; Tani, Pekka; Hokkanen, Laura

2009-01-01

The project Adult Dyslexia and Attention Deficit Disorder in Finland (Project DyAdd) compares adults (n = 119, 18-55 years) with dyslexia, attention-deficit/hyperactivity disorder (ADHD), dyslexia together with ADHD (comorbid), and healthy controls with neuropsychological, psychophysical, and biological methods. The focus of this article is on the…

An Old Problem with New Directions: Maori Language Revitalisation and the Policy Ideas of Youth

ERIC Educational Resources Information Center

Albury, Nathan John

2016-01-01

Legislative changes are afoot in New Zealand that are formalising an ideological shift in policy that decreasingly positions the Maori language a matter of interethnic national identity but increasingly as one for Maori self-determination. The Waitangi Tribunal (WAI262, Waitangi Tribunal, 2011) established that, from here on, Maori language policy…

Implications for Educational Classification and Psychological Diagnoses Using the Wechsler Adult Intelligence Scale-Fourth Edition with Canadian versus American Norms

ERIC Educational Resources Information Center

Harrison, Allyson G.; Holmes, Alana; Silvestri, Robert; Armstrong, Irene T.

2015-01-01

Building on a recent work of Harrison, Armstrong, Harrison, Iverson and Lange which suggested that Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) scores might systematically overestimate the severity of intellectual impairments if Canadian norms are used, the present study examined differences between Canadian and American derived…

Commentary: Where All Children Blossom--Cultural Advantage, Double Win, and Rich Cultural Learning Environments

ERIC Educational Resources Information Center

Lee, Tiffany S.

2017-01-01

The article, ''Mohala i ka wai: Cultural Advantage as a Framework for Indigenous Culture-Based Education and Student Outcomes,'' by Shawn Malia Kana'iaupuni, Brandon Ledward, and Nolan Malone, represents an important story and study in Indigenous educational self-determination. Their positioning and findings of culture as an advantage in regard to…

The Use of Psychological Tests in Predicting Vocational Success of Disadvantaged Adults.

ERIC Educational Resources Information Center

Stanley, Charlton S.

A study of the relationship between certain test scores and probable training and vocational success was made. Examined were three major training areas: power sewing machine, nurse aide, and clerical office work. Six tests were tested for their ability to predict success: the WAIS Revised Beta; Purdue Pegboard; English, California Surveys of…

[Demons-Meigs syndrome: information on a new case and review of the literature].

PubMed

Boufettal, H; Zaghba, N; Morad, S; Bakhatar, A; Yassine, N; Bahlaoui, A; Noun, M; Hermas, S; Samouh, N

2011-04-01

Demons-Meigs syndrome is a benign tumor of the ovary. It is very rare and its physiopathology remains obscure. We report a case of Demons-Meigs syndrome in a woman aged 51 years. It was discovered following a right pleural effusion syndrome with ascites and an abdominopelvic mass. Rate of serum CA 125 was 412IU/mL. Surgical exploration revealed ascites of one litre with no suspicious peritoneal lesion and an ovarian fibrothecoma of 70 mm. There were no post-operative complications and three months later, the level of CA 125 was negative with a total drainage of effusions. Copyright © 2011. Published by Elsevier Masson SAS.

Intelligent Use of Intelligence Tests: Empirical and Clinical Support for Canadian WAIS-IV Norms

ERIC Educational Resources Information Center

Miller, Jessie L.; Weiss, Lawrence G.; Beal, A. Lynne; Saklofske, Donald H.; Zhu, Jianjun; Holdnack, James A.

2015-01-01

It is well established that Canadians produce higher raw scores than their U.S. counterparts on intellectual assessments. As a result of these differences in ability along with smaller variability in the population's intellectual performance, Canadian normative data will yield lower standard scores for most raw score points compared to U.S. norms.…

78 FR 56860 - Honey From the People's Republic of China: Final Results of Antidumping Duty Administrative...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-16

... Global Logistics (Shanghai) Co. 10. Baiste Trading Co., Ltd. 11. Cheng Du Wai Yuan Bee Products Co., Ltd... Industry Co., Ltd. 15. Eurasia Bee's Products Co., Ltd. 16. Feidong Foreign Trade Co., Ltd. 17. Fresh Honey... Healthy Products Co. Ltd. 23. Hubei Yusun Co., Ltd. 24. Inner Mongolia Altin Bee-Keeping 25. Inner...

78 FR 38941 - Honey From the People's Republic of China: Preliminary Results and Partial Rescission of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-28

...., Shanghai Taiside Trading Co., Ltd., Tianjin Eulia Honey Co., Ltd., and Wuhan Bee Healthy Co., Ltd. as... Cheng Du Wai Yuan Bee Products Co., Ltd. 12 Chengdu Stone Dynasty Art Stone 13 Damco China Limited Qingdao Branch 14 Eurasia Bee's Products Co., Ltd. 15 Feidong Foreign Trade Co., Ltd. 16 Fresh Honey Co...

A Four- and Five-Factor Structural Model for Wechsler Tests: Does It Really Matter Clinically?

ERIC Educational Resources Information Center

Schwartz, David M.

2013-01-01

The purpose of this commentary is to focus on the clinical utility of the four- and five-factor structural models for the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) and Wechsler Intelligence Scale for Children-Fourth Edition (WISC-IV). It provides a discussion of important considerations when evaluating the clinical utility of the…

Intelligent Testing with Wechsler’s Fourth Editions: Perspectives on the Weiss et al. Studies and the Eight Commentaries

ERIC Educational Resources Information Center

Kaufman, Alan S.

2013-01-01

The two featured articles and eight commentaries on the WISC-IV (Wechsler, 2003) and WAIS-IV (Wechsler, 2008) in this special issue of "Journal of Psychoeducational Assessment" are of exceptional quality. As a collective, this special issue greatly advances the field of cognitive assessment by intelligently synthesizing the best of…

Sex Differences in Mental Arithmetic, Digit Span, and "g" Defined as Working Memory Capacity

ERIC Educational Resources Information Center

Lynn, Richard; Irwing, Paul

2008-01-01

Meta-analyses are presented of sex differences in (1) the (mental) arithmetic subtest of the Wechsler intelligence tests for children and adolescents (the WISC and WPPSI tests), showing that boys obtained a mean advantage of 0.11d; (2) the (mental) arithmetic subtest of the Wechsler intelligence tests for adults (the WAIS tests) showing a mean…

Getting Back to the Main Point: A Reply to Miller et al.

ERIC Educational Resources Information Center

Harrison, Allyson G.; Holmes, Alana; Silvestri, Robert; Armstrong, Irene T.

2015-01-01

Miller et al. have challenged the findings of our two previous studies, based largely on the assumption that our findings are biased due to the clinical sample used. However, they fail to address the primary tenet of our studies, namely, that clinicians will obtain different scores on the Wechsler Adult Intelligence Scale-IV (WAIS-IV) depending on…

Differences between Toxoplasma Gondii Infected and Non-Infected Blind and Partially Sighted Children and Adolescents on WISC and WAIS Verbal Subtests.

ERIC Educational Resources Information Center

Langset, Marit; And Others

1981-01-01

Children and adolescents who had positive Dye Tests for toxoplasmosis had lower performances on all verbal subtests than those with negative Dye Tests. The impairment was comparable to subjects with brain damage. Subjects with congenital sight deficiency and positive Dye Tests showed progressive intellectual impairments. (Author/CM)

Effects of hamstring stretch with pelvic control on pain and work ability in standing workers.

PubMed

Han, Hyun-Il; Choi, Ho-Suk; Shin, Won-Seob

2016-11-21

Hamstring tightness induces posterior pelvic tilt and decreased lumbar lordosis, which can result in low back painOBJECTIVE: We investigated effects of hamstring stretch with pelvic control on pain and work ability in standing workers. One hundred adult volunteers from a standing workers were randomly assigned to pelvic control hamstring stretching (PCHS) (n = 34), general hamstring stretching (GHS) (n = 34), control (n = 32) groups. The control group was performed self-home exercise. All interventions were conducted 3 days per week for 6 weeks, and included in the hamstring stretching and lumbopelvic muscle strengthening. Outcomes were evaluated through the visual analog scale (VAS), straight leg raise test (SLR), sit and reach test (SRT), Oswestry disability index (ODI), and work ability index (WAI). Significant difference in VAS, SLR, SRT, ODI, and WAI were found in the PCHS and GHS groups. The control group was a significant difference only in ODI. The PCHS group showed a greater difference than the GHS group and control group in VAS, SLR, SRT, and ODI. The pelvic control hamstring stretch exercise would be more helpful in back pain reduction and improvement of work ability in an industrial setting.

Genetic influences on free and cued recall in long-term memory tasks.

PubMed

Volk, Heather E; McDermott, Kathleen B; Roediger, Henry L; Todd, Richard D

2006-10-01

Long-term memory (LTM) problems are associated with many psychiatric and neurological illnesses and are commonly measured using free and cued recall tasks. Although LTM has been linked with biologic mechanisms, the etiology of distinct LTM tasks is unknown. We studied LTM in 95 healthy female twin pairs identified through birth records in the state of Missouri. Performance on tasks of free recall of unrelated words, free and cued recall of categorized words, and the vocabulary section of the Wechsler Adult Intelligence Scale (WAIS-R) were examined using structural equation modeling. Additive genetic and unique environmental factors influenced LTM and intelligence. Free recall of unrelated and categorized words, and cued recall of categorized words, were moderately heritable (55%, 38%, and 37%). WAIS-R vocabulary score was highly heritable (77%). Controlling for verbal intelligence in multivariate analyses of recall, two components of genetic influence on LTM were found; one for all three recall scores and one for free and cued categorized word recall. Recall of unrelated and categorized words is influenced by different genetic and environmental factors indicating heterogeneity in LTM. Verbal intelligence is etiologically different from LTM indicating that these two abilities utilize different brain functions.

The relationship between meeting of recommendations on physical activity for health and perceived work ability among white-collar workers.

PubMed

Nawrocka, Agnieszka; Garbaciak, Wiesław; Cholewa, Jarosław; Mynarski, Władysław

2018-04-01

The aim of this study was to evaluate the association between meeting recommendations on physical activity for health in leisure-time and the ability to work among Polish white-collar workers. The study used a cross-sectional design with a convenience sample of 360 white-collar workers. Participants recorded 7-day physical activity logs, including form, duration and intensity of leisure-time physical activities. The results were compared to health recommendations. A standardized Work Ability Index (WAI) questionnaire was used in assessing the ability to work. Participants who met health recommendations achieved higher scores of the WAI (mean score = 41.93) in comparison to those who were not sufficiently physically active (mean score = 39.35) (p < .001). The results of binary logistic regression show that meeting health-related physical activity recommendations almost double the odds of reaching at least good work ability (OR = 1.94, 95% CI = 1.12-3.36). Meeting leisure-time physical activity recommendations (especially the criterion of vigorous physical activity) is significantly related to higher self-assessed ability to work among white-collar workers.

Patient-Clinician Ethnic Concordance and Communication in Mental Health Intake Visits

PubMed Central

Alegría, Margarita; Roter, Debra L.; Valentine, Anne; Chen, Chih-nan; Li, Xinliang; Lin, Julia; Rosen, Daniel; Lapatin, Sheri; Normand, Sharon-Lise; Larson, Susan; Shrout, Patrick E.

2013-01-01

Objective This study examines how communication patterns vary across racial and ethnic patient-clinician dyads in mental health intake sessions and its relation to continuance in treatment, defined as attending the next scheduled appointment. Methods Observational study of communication patterns among ethnically/racially concordant and discordant patient-clinician dyads. Primary analysis included 93 patients with 38 clinicians in race/ethnic concordant and discordant dyads. Communication was coded using the Roter Interaction Analysis System (RIAS) and the Working Alliance Inventory Observer (WAI-O) bond scale; continuance in care was derived from chart reviews. Results Latino concordant dyad patients were more verbally dominant (p<.05), engaged in more patient-centered communication (p<.05) and scored higher on the (WAI-O) bond scale (all p<.05) than other groups. Latino patients had higher continuance rates than other patients in models that adjusted for non-communication variables. When communication, global affect, and therapeutic process variables were adjusted for, differences were reversed and white dyad patients had higher continuance in care rates than other dyad patients. Conclusion Communication patterns seem to explain the role of ethnic concordance for continuance in care. Practice Implications Improve intercultural communication in cross cultural encounters appears significant for retaining minorities in care. PMID:23896127

Association of interleukin-1β genetic polymorphisms with cognitive performance in elderly females without dementia.

PubMed

Sasayama, Daimei; Hori, Hiroaki; Teraishi, Toshiya; Hattori, Kotaro; Ota, Miho; Matsuo, Junko; Kawamoto, Yumiko; Kinoshita, Yukiko; Higuchi, Teruhiko; Amano, Naoji; Kunugi, Hiroshi

2011-08-01

Interleukin-1β (IL-1β) is considered to have a role in age-related cognitive decline. A recent study has shown that a promoter polymorphism of the IL-1β gene (rs16944) is associated with cognitive performance in elderly males without dementia. In this study, we examined whether polymorphisms of the IL-1β gene also influence cognitive functions in elderly females. Cognitive functions were assessed by the Wechsler adult intelligence scale-revised (WAIS-R) in 99 elderly (60 years) females without dementia. We selected five tagging polymorphisms from the IL-1β gene and examined the associations with the WAIS-R scores. Significant associations were found between verbal intelligence quotient (IQ) and the genotypes of rs1143634 and rs1143633 (P=0.0037 and P=0.010, respectively). No significant associations of rs16944 genotype were found with verbal or performance IQ. However, individuals homozygous for the G allele of rs16944 achieved higher scores in digit span compared with their counterpart, which is consistent with the previous findings in males. These results suggest that IL-1β gene variation may have a role in cognitive functions in aging females as well as males.

Incidental recall on WAIS-R digit symbol discriminates Alzheimer's and Parkinson's diseases.

PubMed

Demakis, G J; Sawyer, T P; Fritz, D; Sweet, J J

2001-03-01

The purpose of this study was to examine how Alzheimer's (n = 37) and Parkinson's (n = 21) patients perform on the incidental recall adaptation to the Digit Symbol of the Wechsler Adult Intelligence Scale-Revised (WAIS-R) and how such performance is related to established cognitive efficiency and memory measures. This adaptation requires the examinee to complete the entire subtest and then, without warning, to immediately recall the symbols associated with each number. Groups did not differ significantly on standard Digit Symbol administration (90 seconds), but on recall Parkinson's patients recalled significantly more symbols and symbol-number pairs than Alzheimer's patients. Using only the number of symbols recalled, discriminate function analysis correctly classified 76% of these patients. Correlations between age-corrected scaled score, symbols incidentally recalled, and established measures of cognitive efficiency and memory provided evidence of convergent and divergent validity. Age-corrected scaled scores were more consistently and strongly related to cognitive efficiency, whereas symbols recalled were more consistently and strongly related to memory measures. These findings suggest that the Digit Symbol recall adaptation is actually assessing memory and that it can be another useful way to detect memory impairment. Copyright 2001 John Wiley & Sons, Inc.

Dating Antarctic ice sheet collapse: Proposing a molecular genetic approach

NASA Astrophysics Data System (ADS)

Strugnell, Jan M.; Pedro, Joel B.; Wilson, Nerida G.

2018-01-01

Sea levels at the end of this century are projected to be 0.26-0.98 m higher than today. The upper end of this range, and even higher estimates, cannot be ruled out because of major uncertainties in the dynamic response of polar ice sheets to a warming climate. Here, we propose an ecological genetics approach that can provide insight into the past stability and configuration of the West Antarctic Ice Sheet (WAIS). We propose independent testing of the hypothesis that a trans-Antarctic seaway occurred at the last interglacial. Examination of the genomic signatures of bottom-dwelling marine species using the latest methods can provide an independent window into the integrity of the WAIS more than 100,000 years ago. Periods of connectivity facilitated by trans-Antarctic seaways could be revealed by dating coalescent events recorded in DNA. These methods allow alternative scenarios to be tested against a fit to genomic data. Ideal candidate taxa for this work would need to possess a circumpolar distribution, a benthic habitat, and some level of genetic structure indicated by phylogeographical investigation. The purpose of this perspective piece is to set out an ecological genetics method to help resolve when the West Antarctic Ice Shelf last collapsed.

Wechsler Adult Intelligence Scale-Fourth Edition performance in relapsing-remitting multiple sclerosis.

PubMed

Ryan, Joseph J; Gontkovsky, Samuel T; Kreiner, David S; Tree, Heather A

2012-01-01

Forty patients with relapsing-remitting multiple sclerosis (MS) completed the 10 core Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) subtests. Means for age and education were 42.05 years (SD = 9.94) and 14.33 years (SD = 2.40). For all participants, the native language was English. The mean duration of MS diagnosis was 8.17 years (SD = 7.75), and the mean Expanded Disability Status Scale (EDSS; Kurtzke, 1983 ) score was 3.73 (SD = 1.41) with a range from 2.0 to 6.5. A control group of healthy individuals with similar demographic characteristics also completed the WAIS-IV and were provided by the test publisher. Compared to controls, patients with MS earned significantly lower subtest and composite scores. The patients' mean scores were consistently in the low-average to average range, and the patterns of performance across groups did not differ significantly, although there was a trend towards higher scores on the Verbal Comprehension Index (VCI) and lower scores on the Processing Speed Index (PSI). Approximately 78% of patients had actual Full Scale IQs that were significantly lower than preillness, demographically based IQ estimates.

Comparison between β-thalassemia minor and normal individuals using the Wechsler Adult Intelligence Scale.

PubMed

Zangiabadi, Nasser; Yarahmadi, Fahimeh; Darekordi, Ali; Shabani, Mohammad; Dadgar, Mehrak Memaran

2013-01-01

The present study aimed at investigating and comparing patients suffering from β-thalassemia (β-thal) minor with normal individuals in regard to their performances in the short version of the Wechsler Adult Intelligence Scale (WAIS) test. Patients with β-thal minor are carriers of β-thal genes. They have mild microcytic and hypochromic anemia and are usually asymptomatic. In this cross-sectional study, a total of 60 individuals were divided into two equal groups of β-thal minor and normal subjects; they were then studied by the WAIS subscales. The mean performance scores of the normal group in the subtests of arithmetic and vocabulary (p <0.01) and picture completion (p <0.05) were higher than those of the thalassemia group. The mean performance score and ability of the normal group on the verbal scale was higher in comparison to the thalassemia group (p <0.05), while on the non verbal scale, there was no significant difference between the two groups. It can be concluded that β-thal minor negatively influences verbal fluency, reasoning and conceptualization, and sequencing tasks, perceptual skill, prediction of social situations and abstract thinking.

Questioning the rule of thumb: can verbal tasks be administered during the CVLT-II delay interval?

PubMed

Williams, Bethany R; Donovick, Peter J

2008-09-01

In the manual for the California Verbal Learning Test - II (CVLT-II), the authors suggest that nonverbal, rather than verbal, tasks be administered during the delay interval between administrations of the Short- and Long-Delay Recall trials of this test. They contend that this method minimizes the retroactive interference produced by intervening tasks. The purpose of the current study was to compare the extent to which verbal and nonverbal intervening tasks produce retroactive interference on CVLT-II List A recall following the long-delay. Participants in the present study were 120 undergraduate students. All participants completed the CVLT-II, and were randomly assigned to a group in which they were administered either a verbal (WAIS-III Vocabulary or Peabody Picture Vocabulary Test - IIIB) or nonverbal (Raven's Standard Progressive Matrices or WAIS-III Block Design) intervening task during the long-delay interval of the CVLT-II. Statistical analyses revealed that regardless of the type of intervening task given, participants in all groups recalled the same number of words and produced a similar number of intrusions during the CVLT-II recall trials. This indicates that not all verbal tasks produce retroactive effects beyond those produced by nonverbal tasks.

Prefrontal cortex activity during response selection predicts processing speed impairment in schizophrenia

PubMed Central

Woodward, Neil D.; Duffy-Alberto, Brittney; Karbasforoushan, Haleh

2014-01-01

Processing speed is the most impaired neuropsychological domain in schizophrenia and a robust predictor of functional outcome. Determining the specific cognitive operations underlying processing speed dysfunction and indentifying their neural correlates may assist in developing pro-cognitive interventions. Response selection, the process of mapping stimuli onto motor responses, correlates with neuropsychological tests of processing speed and may contribute to processing speed impairment in schizophrenia. This study investigated the relationship between behavioral and neural measures of response selection, and a neuropsychological index of processing speed in schizophrenia. 26 patients with schizophrenia and 21 healthy subjects underwent fMRI scanning during performance of 2 and 4-choice-reaction time (RT) tasks and completed the Wechsler Adult Intelligence Scale-III (WAIS) Processing Speed Index (PSI). Response selection, defined as RT slowing between 2 and 4-choice RT, was impaired in schizophrenia and correlated with psychometric processing speed. Greater activation of the dorsolateral prefrontal cortex (PFC) was observed in schizophrenia and correlated with poorer WAIS PSI scores. Deficient response selection and abnormal recruitment of the dorsolateral PFC during response selection contribute to processing speed impairment in schizophrenia. Interventions that improve response selection and normalize dorsolateral PFC function may improve processing speed in schizophrenia. PMID:23816240

Health Conditions and Factors Related to the Work Ability of Teachers

PubMed Central

VEDOVATO, Tatiana Giovanelli; MONTEIRO, Inês

2014-01-01

This is a cross-sectional study conducted with 258 teachers from nine state schools in two municipalities of São Paulo state with the purpose of assessing their work ability. A questionnaire with socio-demographic and health/work conditions data and the Work Ability Index (WAI) was performed. Most teachers were females, 41.9 yr old on average (SD 9.4), and with an undergraduate degree (95.7%). The work ability was considered good for 42.6% and moderate/low for 35.3%. In linear regressions models, which used the two domain model, the significant variables for a decrease in WAI were: individual perception of a worsening in the health situation (p<0001), having children (p=0.0003 / p=0.0001), difficulty in sleeping well at night (p=0.0009 / p=0.0014), history of physical pain in the previous six months (p<0.0001 / p<0.0001), being a teacher with a contract (p=0.0007) and working as a teacher for a longer time. (p=0.0183). Public investments on the work conditions of teachers are important to recover and to maintain their work ability. PMID:24429517

Wisconsin Card Sorting Test performance over time in schizophrenia. Preliminary evidence from clinical follow-up and neuroleptic reduction studies.

PubMed

Seidman, L J; Pepple, J R; Faraone, S V; Kremen, W S; Cassens, G; McCarley, R W; Tsuang, M T

1991-10-01

Two groups of schizophrenic patients took the Wisconsin Card Sorting Test (WCST) in separate follow-up studies; a naturalistic clinical follow-up (n = 12, study 1) and a neuroleptic reduction study (n = 10, study 2). 11 of 22 subjects (50%) performed well on the task at one or both time points. In each study no group differences were found between time 1 and time 2 performance on three WCST variables. However, correlational analyses revealed considerable within-subject variation on the WCST in the study 1 sample, which was composed of younger and more acute patients than those in study 2. This variation was present despite within-subject stability on the WAIS-R Vocabulary and Block Design subtests. For the sample combined, a trend was found (p = 0.12) linking better WCST performance at either time period with higher WAIS-R Vocabulary scores. This intra-subject variability may reflect fluctuations in neuropsychological performance in schizophrenics who maintain the residual capacity to do the task. These findings highlight the importance of longitudinal studies of neuropsychological functioning in schizophrenia. Studies of larger samples are needed to confirm these initial results.

Usefulness of the Wechsler Intelligence Scale short form for assessing functional outcomes in patients with schizophrenia.

PubMed

Sumiyoshi, Chika; Fujino, Haruo; Sumiyoshi, Tomiki; Yasuda, Yuka; Yamamori, Hidenaga; Ohi, Kazutaka; Fujimoto, Michiko; Takeda, Masatoshi; Hashimoto, Ryota

2016-11-30

The Wechsler Adult Intelligence Scale (WAIS) has been widely used to assess intellectual functioning not only in healthy adults but also people with psychiatric disorders. The purpose of the study was to develop an optimal WAIS-3 short form (SF) to evaluate intellectual status in patients with schizophrenia. One hundred and fifty patients with schizophrenia and 221 healthy controls entered the study. To select subtests for SFs, following criteria were considered: 1) predictability for the full IQ (FIQ), 2) representativeness for the IQ structure, 3) consistency of subtests across versions, 4) sensitivity to functional outcome measures, 5) conciseness in administration time. First, exploratory factor analysis (EFA) and multiple regression analysis were conducted to select subtests satisfying the first and the second criteria. Then, candidate SFs were nominated based on the third criterion and the coverage of verbal IQ and performance IQ. Finally, the optimality of candidate SFs was evaluated in terms of the fourth and fifth criteria. The results suggest that the dyad of Similarities and Symbol Search was the most optimal satisfying the above criteria. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Physical properties of the WAIS Divide ice core

USGS Publications Warehouse

Fitzpatrick, Joan J.; Voigt, Donald E.; Fegyveresi, John M.; Stevens, Nathan T.; Spencer, Matthew K.; Cole-Dai, Jihong; Alley, Richard B.; Jardine, Gabriella E.; Cravens, Eric; Wilen, Lawrence A.; Fudge, T. J.; McConnell, Joseph R.

2014-01-01

The WAIS (West Antarctic Ice Sheet) Divide deep ice core was recently completed to a total depth of 3405 m, ending ∼50 m above the bed. Investigation of the visual stratigraphy and grain characteristics indicates that the ice column at the drilling location is undisturbed by any large-scale overturning or discontinuity. The climate record developed from this core is therefore likely to be continuous and robust. Measured grain-growth rates, recrystallization characteristics, and grain-size response at climate transitions fit within current understanding. Significant impurity control on grain size is indicated from correlation analysis between impurity loading and grain size. Bubble-number densities and bubble sizes and shapes are presented through the full extent of the bubbly ice. Where bubble elongation is observed, the direction of elongation is preferentially parallel to the trace of the basal (0001) plane. Preferred crystallographic orientation of grains is present in the shallowest samples measured, and increases with depth, progressing to a vertical-girdle pattern that tightens to a vertical single-maximum fabric. This single-maximum fabric switches into multiple maxima as the grain size increases rapidly in the deepest, warmest ice. A strong dependence of the fabric on the impurity-mediated grain size is apparent in the deepest samples.

Low post-glacial rebound rates in the Weddell Sea due to Late Holocene ice-sheet readvance

NASA Astrophysics Data System (ADS)

Bradley, Sarah L.; Hindmarsh, Richard C. A.; Whitehouse, Pippa; Bentley, Michael J.; King, Matt

2014-05-01

The Holocene deglaciation of West Antarctica resulted in widespread ice surface lowering. While many ice-sheet reconstructions generally assume a monotone Holocene retreat for the West Antarctica Ice sheet (WAIS) [Ivins et al., 2013; Peltier, 2004; Whitehouse et al., 2012], an increasing number of glaciological observations infer it is readvancing, following retreat behind the present-day margin[Siegert et al., 2013]. We will show that a readvance in the Weddell Sea region can reconcile two outstanding problems: (i) the present-day widespread occurrence of seemingly stable ice-streams grounded on beds that deepen inland in apparent contradiction to theory [Schoof, 2007]; and (ii) the inability of models of Glacial Isostatic Adjustment (GIA) to match present-day uplift rates [Whitehouse et al., 2012]. Combining a suite of ice loading histories that include a readvance with a model of GIA provides significant improvements to predictions of present-day uplift rates, and we are able to reproduce previously unexplained observations of subsidence in the southern sector of the Weddell Sea. We hypothesize that retreat behind present grounding lines occurred when the bed was lower, and isostatic recovery led to shallowing, ice sheet re-grounding and readvance. We will conclude that some sections of the current WAIS grounding line that are theoretically unstable, may be advancing and that the volume change of the WAIS may have been more complex in the Late Holocene than previously posited. This revised Holocene ice-loading history would have important implications for the GIA correction applied to Gravity Recovery and Climate Experiment (GRACE) data, likely resulting in a reduction in the GIA correction and a smaller estimate of present-day ice mass loss within the Weddell Sea region of the WAIS. Ivins, E. R., T. S. James, J. Wahr, E. J. O. Schrama, F. W. Landerer, and K. M. Simon (2013), Antarctic contribution to sea level rise observed by GRACE with improved GIA correction, Journal of Geophysical Research: Solid Earth, 118(6), 3126-3141. Peltier, W. R. (2004), Global glacial isostasy and the surface of the ice-age earth: The ice-5G (VM2) model and grace, Annu Rev Earth Pl Sc, 32, 111-149. Schoof, C. (2007), Ice sheet grounding line dynamics: Steady states, stability, and hysteresis, Journal of Geophysical Research: Earth Surface, 112(F3). Siegert, M., N. Ross, H. Corr, J. Kingslake, and R. Hindmarsh (2013), Late Holocene ice-flow reconfiguration in the Weddell Sea sector of West Antarctica, Quaternary Sci Rev, 78(0), 98-107. Whitehouse, P. L., M. J. Bentley, G. A. Milne, M. A. King, and I. D. Thomas (2012), A new glacial isostatic adjustment model for Antarctica: calibrated and tested using observations of relative sea-level change and present-day uplift rates, Geophys J Int, 190(3), 1464-1482.

Whole Abdominopelvic Intensity-Modulated Radiation Therapy for Desmoplastic Small Round Cell Tumor After Surgery

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pinnix, Chelsea C.; Fontanilla, Hiral P.; Hayes-Jordan, Andrea

2012-05-01

Purpose: Desmoplastic small round cell tumor (DSCRT) is an uncommon pediatric tumor with a poor prognosis. Aggressive multimodality therapy is the current treatment approach; however. treatment toxicity is of concern. We report our results with whole abdominopelvic intensity-modulated radiation therapy (WAP-IMRT) as a component of multimodality therapy for DSCRT at a single institution. Materials/Methods: Medical records of all patients with DSCRT who received WAP-IMRT as part of definitive treatment at MD Anderson (2006-2010) were identified and reviewed. Results: Eight patients with DSRCT received WAP-IMRT with a median follow-up of 15.2 months. All patients received multiple courses of chemotherapy followed bymore » surgical debulking of intra-abdominal disease; seven also had intraoperative hyperthermic cisplatin. WAP-IMRT was delivered to a total dose of 30 Gy postoperatively; four patients received a simultaneous boost (6-10 Gy) to sites of gross residual disease. Seven patients received concurrent chemotherapy during WAP-IMRT. No Radiation Therapy Oncology Group Grade 4 nausea, vomiting, or diarrhea occurred during RT. Red-cell transfusions were given to two patients to maintain hemoglobin levels >10 g/dL. Grade 4 cytopenia requiring growth factor support occurred in only one patient; no other significant cytopenias were noted. WAP-IMRT resulted in 25% lower radiation doses to the lumbosacral vertebral bodies and pelvic bones than conventional RT plans. The median time to local or distant failure after WAP-IMRT was 8.73 months in seven patients. One patient who had completed RT 20 months before the last follow-up remains alive without evidence of disease. Five patients (63%) experienced treatment failure in the abdomen. Distant failure occurred in three patients (37.5%). Conclusions: WAP-IMRT with concurrent radiosensitizing chemotherapy was well tolerated after aggressive surgery for DSCRT. Enhanced bone sparing with IMRT probably accounts for the low hematologic toxicity (vs. conventional WAP-RT). This modality should be considered as an additional local-regional control option for DSRCT.« less

Differentiation of deep venous thrombosis from femoral vein mixing artifact on routine abdominopelvic CT.

PubMed

Doshi, Ankur M; Hoffman, David; Kierans, Andrea S; Ream, Justin M; Rosenkrantz, Andrew B

2015-10-01

The objective of this study is to assess the performance of qualitative and quantitative imaging features for the differentiation of deep venous thrombosis (DVT) from mixing artifact on routine portal venous phase abdominopelvic CT. This retrospective study included 40 adult patients with a femoral vein filling defect on portal venous phase CT and a Duplex ultrasound (n = 36) or catheter venogram (n = 4) to confirm presence or absence of DVT. Two radiologists (R1, R2) assessed the femoral veins for various qualitative and quantitative features. 60% of patients were confirmed to have DVT and 40% had mixing artifact. Features with significantly greater frequency in DVT than mixing artifact (all p ≤ 0.006) were central location (R1 90% vs. 28%; R2 96% vs. 31%), sharp margin (R1 83% vs. 28%; R2 96% vs. 31%), venous expansion (R1 48% vs. 6%, R2 56% vs. 6%), and venous wall enhancement (R1 62% vs. 0%; R2 48% vs. 0%). DVT exhibited significantly lower mean attenuation than mixing artifact (R1 42.1 ± 20.2 vs. 57.1 ± 23.6 HU; R2 43.6 ± 19.4 vs. 58.8 ± 23.4 HU, p ≤ 0.031) and a significantly larger difference in vein diameter compared to the contralateral vein (R1 0.4 ± 0.4 vs. 0.1 ± 0.2 cm; R2 0.3 ± 0.4 vs. 0.0 ± 0.1 cm, p ≤ 0.026). At multivariable analysis, central location and sharp margin were significant independent predictors of DVT for both readers (p ≤ 0.013). Awareness of these qualitative and quantitative imaging features may improve radiologists' confidence for differentiating femoral vein DVT and mixing artifact on routine portal venous phase CT. However, given overlap with mixing artifact, larger studies remain warranted.

TU-H-207A-09: An Automated Technique for Estimating Patient-Specific Regional Imparted Energy and Dose From TCM CT Exams Across 13 Protocols

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sanders, J; Tian, X; Segars, P

2016-06-15

Purpose: To develop an automated technique for estimating patient-specific regional imparted energy and dose from tube current modulated (TCM) computed tomography (CT) exams across a diverse set of head and body protocols. Methods: A library of 58 adult computational anthropomorphic extended cardiac-torso (XCAT) phantoms were used to model a patient population. A validated Monte Carlo program was used to simulate TCM CT exams on the entire library of phantoms for three head and 10 body protocols. The net imparted energy to the phantoms, normalized by dose length product (DLP), and the net tissue mass in each of the scan regionsmore » were computed. A knowledgebase containing relationships between normalized imparted energy and scanned mass was established. An automated computer algorithm was written to estimate the scanned mass from actual clinical CT exams. The scanned mass estimate, DLP of the exam, and knowledgebase were used to estimate the imparted energy to the patient. The algorithm was tested on 20 chest and 20 abdominopelvic TCM CT exams. Results: The normalized imparted energy increased with increasing kV for all protocols. However, the normalized imparted energy was relatively unaffected by the strength of the TCM. The average imparted energy was 681 ± 376 mJ for abdominopelvic exams and 274 ± 141 mJ for chest exams. Overall, the method was successful in providing patientspecific estimates of imparted energy for 98% of the cases tested. Conclusion: Imparted energy normalized by DLP increased with increasing tube potential. However, the strength of the TCM did not have a significant effect on the net amount of energy deposited to tissue. The automated program can be implemented into the clinical workflow to provide estimates of regional imparted energy and dose across a diverse set of clinical protocols.« less

Human- Versus System-Level Factors and Their Effect on Electronic Work List Variation: Challenging Radiology's Fundamental Attribution Error.

PubMed

Davenport, Matthew S; Khalatbari, Shokoufeh; Platt, Joel F

2015-09-01

The aim of this study was to analyze sources of variation influencing the unread volume on an electronic abdominopelvic CT work list and to compare those results with blinded radiologist perception. The requirement for institutional review board approval was waived for this HIPAA-compliant quality improvement effort. Data pertaining to an electronic abdominopelvic CT work list were analyzed retrospectively from July 1, 2013, to June 30, 2014, and modeled with respect to the unread case total at 6 pm (Monday through Friday, excluding holidays). Eighteen system-level factors outside individual control (eg, number of workers, workload) and 7 human-level factors within individual control (eg, individual productivity) were studied. Attending radiologist perception was assessed with a blinded anonymous survey (n = 12 of 15 surveys completed). The mean daily unread total was 24 (range, 3-72). The upper control limit (48 CT studies [3 SDs above the mean]) was exceeded 10 times. Multivariate analysis revealed that the rate of unread CT studies was affected principally by system-level factors, including the number of experienced trainees on service (postgraduate year 5 residents [odds ratio, 0.83; 95% confidence interval, 0.74-0.92; P = .0008] and fellows [odds ratio, 0.84; 95% confidence interval, 0.74-0.95; P = .005]) and the daily workload (P = .02 to P < .0001). Individual faculty productivity had a weak effect (Spearman ρ = 0.13, P = .03; adequacy: 3% of variance explained). The majority (67%) of radiologists (8 of 12) completing the survey believed that variation in faculty effort was the most important influence on the daily unread total. System-level factors best predict the variation in unread CT examinations, but blinded faculty radiologists believe that it relates most strongly to variable individual effort. Copyright © 2015 American College of Radiology. Published by Elsevier Inc. All rights reserved.

Computed Tomography Image Quality Evaluation of a New Iterative Reconstruction Algorithm in the Abdomen (Adaptive Statistical Iterative Reconstruction-V) a Comparison With Model-Based Iterative Reconstruction, Adaptive Statistical Iterative Reconstruction, and Filtered Back Projection Reconstructions.

PubMed

Goodenberger, Martin H; Wagner-Bartak, Nicolaus A; Gupta, Shiva; Liu, Xinming; Yap, Ramon Q; Sun, Jia; Tamm, Eric P; Jensen, Corey T

The purpose of this study was to compare abdominopelvic computed tomography images reconstructed with adaptive statistical iterative reconstruction-V (ASIR-V) with model-based iterative reconstruction (Veo 3.0), ASIR, and filtered back projection (FBP). Abdominopelvic computed tomography scans for 36 patients (26 males and 10 females) were reconstructed using FBP, ASIR (80%), Veo 3.0, and ASIR-V (30%, 60%, 90%). Mean ± SD patient age was 32 ± 10 years with mean ± SD body mass index of 26.9 ± 4.4 kg/m. Images were reviewed by 2 independent readers in a blinded, randomized fashion. Hounsfield unit, noise, and contrast-to-noise ratio (CNR) values were calculated for each reconstruction algorithm for further comparison. Phantom evaluation of low-contrast detectability (LCD) and high-contrast resolution was performed. Adaptive statistical iterative reconstruction-V 30%, ASIR-V 60%, and ASIR 80% were generally superior qualitatively compared with ASIR-V 90%, Veo 3.0, and FBP (P < 0.05). Adaptive statistical iterative reconstruction-V 90% showed superior LCD and had the highest CNR in the liver, aorta, and, pancreas, measuring 7.32 ± 3.22, 11.60 ± 4.25, and 4.60 ± 2.31, respectively, compared with the next best series of ASIR-V 60% with respective CNR values of 5.54 ± 2.39, 8.78 ± 3.15, and 3.49 ± 1.77 (P <0.0001). Veo 3.0 and ASIR 80% had the best and worst spatial resolution, respectively. Adaptive statistical iterative reconstruction-V 30% and ASIR-V 60% provided the best combination of qualitative and quantitative performance. Adaptive statistical iterative reconstruction 80% was equivalent qualitatively, but demonstrated inferior spatial resolution and LCD.

What factors are associated with increased risk for prolonged postoperative opioid usage after colorectal surgery?

PubMed

Stafford, Caitlin; Francone, Todd; Roberts, Patricia L; Ricciardi, Rocco

2018-02-06

Opioid-related deaths have increased substantially over the last 10 years placing clinician's prescription practices under intense scrutiny. Given the substantial risk of opioid dependency after colorectal surgery, we sought to analyze risk of postoperative prolonged opioid use after colorectal resections. Between 2008 and 2014, patients undergoing abdominopelvic procedure with intestinal resection at a tertiary care facility were retrospectively identified. Patient's postoperative narcotic usage including their prescriptions on discharge and their total opioid medication use was recorded. Patient variables such as demographics, surgical characteristics, and prescription use were evaluated. Finally, we developed multivariate models to identify risk factors for prolonged opioid use (> 30 days after incident surgical procedure). We identified 9423 recorded procedures of which 2173 consisted of abdominopelvic procedures with intestinal resection and survived > 1 year. Of these, 91% (n = 1981) were discharged on opioids, and 98% (n = 1955) of those patients filled only one prescription. A total of 92 (4%) patients remained on opioids beyond 30 days, and from this group, 25% (n = 23 patients) remained at 90 days. We found no association between postoperative complications, stoma formation, and patient's sex with risk of prolonged opioid use. However, younger age and history of chronic pain were associated with an increased risk of prolonged opioid use. The use of minimally invasive techniques also attenuated the risk of prolonged opioid use (Table 2). A small but considerable proportion of patients remain on opioids beyond 30 days. Predictors of opioid use for greater than 30 days include a history of chronic pain and younger age. The use of minimally invasive techniques reduced the risk of prolonged opioid use. We identified several immutable risk factors that predicted prolonged postoperative opioid use; however, surgeons may be able to attenuate prolonged opioid use through the use of minimally invasive techniques.

Laser Initiated Ignition of Liquid Propellant

DTIC Science & Technology

1991-01-31

containers held in a water bath of constant temperature 70*C. A larger vessel containing approximately 2ml of propellant was also heated in each experiment and...controller. A stirrer and forced water circulation ensured that all samples were kept at the same temperature. The water wai first heated to the final 5... electrolysed samples. 3 .. .. ....... ......................... volume of 10 ....... . 5 ....... I • . ... .. . .... .. ...... .. . . .. . . ... . .61.8 2 22i

Quality of Life of Poor People Living in Remote Areas in Hong Kong

ERIC Educational Resources Information Center

Wong, Hung

2011-01-01

Based on three surveys carried out for studying living conditions of youth, women and elderly living in six remote areas (Tuen Mun, Yuen Long, Tin Shui Wai, Sheung Shui, Fan Ling and Tai Po) in the New Territories of Hong Kong, this paper reports the poverty and social exclusion of these three groups of people. The quality of life of youth, women…

The Interflow of Two Rivers: An Inter-School CSCL Project on Improving Water Quality by Using Videoconferencing

ERIC Educational Resources Information Center

Fung, Leo Sun-wai; Chan, Yu-nang

2009-01-01

The aim of this research is to study the effectiveness of using videoconferencing as a tool for collaborative learning on water pollution among students from two secondary schools located in different districts. The poor water quality of the nullahs in urban areas aroused the interest of students from two secondary schools in Tin Shui Wai and Wong…

Changes in Word Usage Frequency May Hamper Intergenerational Comparisons of Vocabulary Skills: An Ngram Analysis of Wordsum, WAIS, and WISC Test Items

ERIC Educational Resources Information Center

Roivainen, Eka

2014-01-01

Research on secular trends in mean intelligence test scores shows smaller gains in vocabulary skills than in nonverbal reasoning. One possible explanation is that vocabulary test items become outdated faster compared to nonverbal tasks. The history of the usage frequency of the words on five popular vocabulary tests, the GSS Wordsum, Wechsler…

A Comparison of Low IQ Scores from the Reynolds Intellectual Assessment Scales and the Wechsler Adult Intelligence Scale--Third Edition

ERIC Educational Resources Information Center

Umphress, Thomas B.

2008-01-01

Twenty people with suspected intellectual disability took the Reynolds Intellectual Assessment Scales (RIAS; C. R. Reynolds & R. W. Kamphaus, 1998) and the Wechsler Adult Intelligence Scale--3rd Edition (WAIS-III; D. Wechsler, 1997) to see if the 2 IQ tests produced comparable results. A t test showed that the RIAS Composite Intelligence Index…

The Use of a Context-Based Information Retrieval Technique

DTIC Science & Technology

2009-07-01

provided in context. Latent Semantic Analysis (LSA) is a statistical technique for inferring contextual and structural information, and previous studies...WAIS). 10 DSTO-TR-2322 1.4.4 Latent Semantic Analysis LSA, which is also known as latent semantic indexing (LSI), uses a statistical and...1.4.6 Language Models In contrast, natural language models apply algorithms that combine statistical information with semantic information. Semantic

Joint Analysis of Two Ability Tests: Two Theories, One Outcome

DTIC Science & Technology

2014-01-01

after the Wechsler Adult Intelligence Scale – Revised (WAIS-R; Wechsler , 1981). It has 10 subtests that produce three summary scores: verbal IQ (VIQ...of the multidimensional aptitude battery. Journal of Clinical Psychology, 45, 429-433. Wechsler , D. (1980). Wechsler Adult Intelligence Scale ...FSIQ MAB Full- Scale Intelligence Quotient MAB Inf MAB Information subtest MAB Oa MAB Object Assembly subtest MAB Pa MAB Picture Arrangement

Validation of the Noncommissioned Officer Special Assignment Battery

DTIC Science & Technology

2013-03-01

scoring designed to reduce the effects of faking in personality assessment [ Doctoral Dissertation]. University of Illinois at Urbana-Champaign. Stark, S...conducted factor analyses to determine whether these scales could be reasonably combined to create a reduced number of criteria for examining WAI and NSAB...has been that previously validated instruments for this purpose required proctored testing. To make it easier for Soldiers to be tested, reduce

Spatio-Temporal Variability of Recent Snow Accumulation Across the West Antarctic Ice Sheet Divide Using Ultra-High Frequency Radar and Shallow Firn Cores

NASA Astrophysics Data System (ADS)

Keeler, D. G.; Rupper, S.; Forster, R. R.; Miège, C.; Brewer, S.; Koenig, L.

2017-12-01

The West Antarctic Ice Sheet (WAIS) could be a substantial source of future sea level rise, with 3+ meters of potential increase stored in the ice sheet. Adequate predictions of WAIS contributions, however, depend on well-constrained surface mass balance estimates for the region. Given the sparsity of available data, such estimates are tenuous. Although new data are periodically added, further research (both to collect more data and better utilize existing data) is critical to addressing these issues. Here we present accumulation data from 9 shallow firn cores and 600 km of Ku band radar traces collected as part of the Satellite Era Antarctic Traverse (SEAT) 2011/2012 field season. Using these data, combined with similar data collected during the SEAT 2010/2011 field season, we investigate the spatial variability in accumulation across the WAIS Divide and surrounding regions. We utilize seismic interpretation and 3D visualization tools to investigate the extent and variations of laterally continuous internal horizons in the radar profiles, and compare the results to nearby firn cores. Previous results show that clearly visible, laterally continuous horizons in radar returns in this area do not always represent annual accumulation isochrones, but can instead represent multi-year or sub-annual events. The automated application of Bayesian inference techniques to averaged estimates of multiple adjacent radar traces, however, can estimate annually-resolved independent age-depth scales for these radar data. We use these same automated techniques on firn core isotopic records to infer past snow accumulation rates, allowing a direct comparison with the radar-derived results. Age-depth scales based on manual annual-layer counting of geochemical and isotopic species from these same cores provide validation for the automated approaches. Such techniques could theoretically be applied to additional radar/core data sets in polar regions (e.g. Operation IceBridge), thereby increasing the number of high resolution accumulation records available in these data-sparse regions. An increased understanding of the variability in magnitude and past rates of surface mass balance can provide better constraints on sea level projections and more precise context for present-day and future observations in these regions.

The level of leisure time physical activity is associated with work ability-a cross sectional and prospective study of health care workers.

PubMed

Arvidson, Elin; Börjesson, Mats; Ahlborg, Gunnar; Lindegård, Agneta; Jonsdottir, Ingibjörg H

2013-09-17

With increasing age, physical capacity decreases, while the need and time for recovery increases. At the same time, the demands of work usually do not change with age. In the near future, an aging and physically changing workforce risks reduced work ability. Therefore, the impact of different factors, such as physical activity, on work ability is of interest. Thus, the aim of this study was to evaluate the association between physical activity and work ability using both cross sectional and prospective analyses. This study was based on an extensive questionnaire survey. The number of participants included in the analysis at baseline in 2004 was 2.783, of whom 2.597 were also included in the follow-up in 2006. The primary outcome measure was the Work Ability Index (WAI), and the level of physical activity was measured using a single-item question. In the cross-sectional analysis we calculated the level of physical activity and the prevalence of poor or moderate work ability as reported by the participants. In the prospective analysis we calculated different levels of physical activity and the prevalence of positive changes in WAI-category from baseline to follow-up. In both the cross sectional and the prospective analyses the prevalence ratio was calculated using Generalized Linear Models. The cross-sectional analysis showed that with an increased level of physical activity, the reporting of poor or moderate work ability decreased. In the prospective analysis, participants reporting a higher level of physical activity were more likely to have made an improvement in WAI from 2004 to 2006. The level of physical activity seems to be related to work ability. Assessment of physical activity may also be useful as a predictive tool, potentially making it possible to prevent poor work ability and improve future work ability. For employers, the main implications of this study are the importance of promoting and facilitating the employees' engagement in physical activity, and the importance of the employees' maintaining a physically active lifestyle.

Long-term risks of subsequent primary neoplasms among survivors of childhood cancer.

PubMed

Reulen, Raoul C; Frobisher, Clare; Winter, David L; Kelly, Julie; Lancashire, Emma R; Stiller, Charles A; Pritchard-Jones, Kathryn; Jenkinson, Helen C; Hawkins, Michael M

2011-06-08

Survivors of childhood cancer are at excess risk of developing subsequent primary neoplasms but the long-term risks are uncertain. To investigate long-term risks of subsequent primary neoplasms in survivors of childhood cancer, to identify the types that contribute most to long-term excess risk, and to identify subgroups of survivors at substantially increased risk of particular subsequent primary neoplasms that may require specific interventions. British Childhood Cancer Survivor Study--a population-based cohort of 17,981 5-year survivors of childhood cancer diagnosed with cancer at younger than 15 years between 1940 and 1991 in Great Britain, followed up through December 2006. Standardized incidence ratios (SIRs), absolute excess risks (AERs), and cumulative incidence of subsequent primary neoplasms. After a median follow-up time of 24.3 years (mean = 25.6 years), 1354 subsequent primary neoplasms were ascertained; the most frequently observed being central nervous system (n = 344), nonmelanoma skin cancer (n = 278), digestive (n = 105), genitourinary (n = 100), breast (n = 97), and bone (n = 94). The overall SIR was 4 times more than expected (SIR, 3.9; 95% confidence interval [CI], 3.6-4.2; AER, 16.8 per 10,000 person-years). The AER at older than 40 years was highest for digestive and genitourinary subsequent primary neoplasms (AER, 5.9 [95% CI, 2.5-9.3]; and AER, 6.0 [95%CI, 2.3-9.6] per 10,000 person-years, respectively); 36% of the total AER was attributable to these 2 subsequent primary neoplasm sites. The cumulative incidence of colorectal cancer for survivors treated with direct abdominopelvic irradiation was 1.4% (95% CI, 0.7%-2.6%) by age 50 years, comparable with the 1.2% risk in individuals with at least 2 first-degree relatives affected by colorectal cancer. Among a cohort of British childhood cancer survivors, the greatest excess risk associated with subsequent primary neoplasms at older than 40 years was for digestive and genitourinary neoplasms.

A rare cause of acute abdominal pain: Herlyn-Werner-Wunderlich syndrome.

PubMed

Aydin, Ramazan; Ozdemir, Ayse Zehra; Ozturk, Bahadir; Bilgici, Meltem Ceyhan; Tosun, Migraci

2014-01-01

Herlyn-Werner-Wunderlich (HWW) syndrome is a rare müllerian duct anomaly with uterus didelphys, unilateral obstructed hemivagina, and ipsilateral renal agenesis. Patients with this syndrome generally present after menarche with pelvic pain and mass and, rarely, primary infertility in later years. Strong suspicion and knowledge of this syndrome are mandatory for an accurate diagnosis. A 14-year-old female patient presented with acute retention of urine and abdominopelvic pain. Her condition was diagnosed with the use ultrasonography and magnetic resonance imaging as a case of HWW syndrome. She was treated with vaginal hemiseptal resection. The HWW syndrome should be considered among the differential diagnoses in girls with renal anomalies presenting with pelvic mass, symptoms of acute abdominal pain, and acute urinary retention.

DELFIC: Department of Defense Fallout Prediction System. Volume I - Fundamentals

DTIC Science & Technology

1979-12-31

102 H2590D. DTIC•;. 17.) 1 i{1•ELECT ’ Prepared for " JAUG 2 ? 1980 Director DEFENSE NUCLEAR AGENCY B Wai’hington, D. C. 20305 808 1O8x Destroy this...2 1. INTRODUCTION AND OVERVIEW -- --- - -------------- - --- ---- 7 2. INITIALIZATION AND CLOUD RISE...61 6 1. INTRODUCTION AND OVERVIEW DELFIC (DEfense Land Fallout Interpretative Code) is intended for re- search in local nuclear fallout

Assessing repository technology. Where do we go from here?

NASA Technical Reports Server (NTRS)

Eichmann, David

1992-01-01

Three sample information retrieval systems, archie, autoLib, and Wide Area Information Service (WAIS), are compared with regard to their expressiveness and usefulness, first in the general context of information retrieval, and then as prospective software reuse repositories. While the representational capabilities of these systems are limited, they provide a useful foundation for future repository efforts, particularly from the perspective of repository distribution and coherent user interface design.

Assessing repository technology: Where do we go from here?

NASA Technical Reports Server (NTRS)

Eichmann, David A.

1992-01-01

Three sample information retrieval systems, archie, autoLib, and Wide Area Information Service (WAIS), are compared with regard to their expressiveness and usefulness, first in the general context of information retrieval, and then as perspective software reuse repositories. While the representational capabilities of these systems are limited, they provide a useful foundation for future repository efforts, particularly from the perspective of repository distribution and coherent user interface design.