Sample records for abl contact address

  1. Challenges in recruiting African-American women for a breast cancer genetics study.

    PubMed

    Compadre, Amanda J; Simonson, Melinda E; Gray, Katy; Runnells, Gail; Kadlubar, Susan; Zorn, Kristin K

    2018-01-01

    African-American women, especially in the southern United States, are underrepresented in cancer genetics research. A study was designed to address this issue by investigating the germline mutation rate in African-American women in Arkansas with a personal and/or family history of breast cancer. Women were tested for these mutations using a large panel of breast cancer susceptibility genes. In this analysis, we discuss the challenges encountered in recruiting African-American women from an existing biorepository to participate in this study. We attempted to contact 965 African-American women with a personal and/or family history of breast cancer who participated in Spit for the Cure (SFTC) between 2007 and 2013 and provided consent to be recontacted. The SFTC participants were invited by telephone and email to participate in the genetic study. Enrollment required completion of a phone interview to obtain a family and medical history and return of a signed consent form. Among eligible SFTC participants, 39.6% (382/965) were able to be contacted with the phone numbers and email addresses they provided. Of these, 174 (45.5%) completed a phone interview and returned a signed consent form. Others were not able to be contacted ( n  = 583), declined to participate ( n  = 57), did not keep phone interview appointments ( n  = 82), completed the phone interview but never returned a signed consent ( n  = 54), were deceased ( n  = 13), or were too confused to consent to participate ( n  = 2). Recruiting African-American women into our breast cancer genetics study proved challenging primarily due to difficulty establishing contact with potential participants. Given their prior participation in breast cancer research, we anticipated that this would be a highly motivated population. Indeed, when we were able to contact SFTC participants, only 14.9% declined to participate in our study. Innovative communication, retention, and recruitment strategies are needed in future studies to address the recruitment challenges we faced.

  2. 75 FR 32767 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-09

    ... difficulties and cannot contact you for clarification, EPA may not be able to consider your comment. Electronic... docket ID number and other identifying information (subject heading, Federal Register date and page... address: Bayer CropScience, P.O. Box 12014, 2 T.W. Alexander Drive, Research Triangle Park, NC 27709...

  3. 40 CFR 710.32 - Reporting information to EPA.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... and which controls the import transaction, and may in some cases be the organization's headquarters... following: (1) The name, company, address, city, State, Zip code, and telephone number of a person who will serve as technical contact for the respondent company, and will be able to answer questions about the...

  4. Non-contact procedure to measure heart and lung activities in preterm pediatric patients with skin disorders

    NASA Astrophysics Data System (ADS)

    Marchionni, P.; Scalise, L.; Antognoli, L.; Nobile, S.; Carnielli, V. P.

    2018-04-01

    Preterm patients can have an higher risk of fatalities and can be subjected to long-term disability. With many organs still in the phase of development, the earlier the delivery, the higher the risk and they are therefore hospitalized in specialized neonatal intensive care units) where heart rate and lungs activity are continuously assessed. These are mostly monitored by set of electrodes placed in contact with skin (two in thorax area and one in abdominal area). This paper address the problem of preterm cardiac and respiratory monitoring in a patient with severe skin disorders who can not monitored with standard electrodes because of his dry, thickened, scaly skin. As a solution, we propose a fully non-contact measurement method, based on laser Doppler vibrometry, able to continuously record the movements of wall-chest and extract from this signal, the heart rate and the respiratory activity of the patient. The results show a good agreement between the standard contact measurement methods and the proposed one (no statistical difference between data) with a data uncertainty of 2.9% for the heart rate data and of 9.5% for the respiration rate (k=2), in line with the classical measurement methods.

  5. Real-time simulation of contact and cutting of heterogeneous soft-tissues.

    PubMed

    Courtecuisse, Hadrien; Allard, Jérémie; Kerfriden, Pierre; Bordas, Stéphane P A; Cotin, Stéphane; Duriez, Christian

    2014-02-01

    This paper presents a numerical method for interactive (real-time) simulations, which considerably improves the accuracy of the response of heterogeneous soft-tissue models undergoing contact, cutting and other topological changes. We provide an integrated methodology able to deal both with the ill-conditioning issues associated with material heterogeneities, contact boundary conditions which are one of the main sources of inaccuracies, and cutting which is one of the most challenging issues in interactive simulations. Our approach is based on an implicit time integration of a non-linear finite element model. To enable real-time computations, we propose a new preconditioning technique, based on an asynchronous update at low frequency. The preconditioner is not only used to improve the computation of the deformation of the tissues, but also to simulate the contact response of homogeneous and heterogeneous bodies with the same accuracy. We also address the problem of cutting the heterogeneous structures and propose a method to update the preconditioner according to the topological modifications. Finally, we apply our approach to three challenging demonstrators: (i) a simulation of cataract surgery (ii) a simulation of laparoscopic hepatectomy (iii) a brain tumor surgery. Copyright © 2013 Elsevier B.V. All rights reserved.

  6. Respiration and heartbeat monitoring using a distributed pulsed MIMO radar.

    PubMed

    Walterscheid, Ingo; Smith, Graeme E

    2017-07-01

    This paper addresses non-contact monitoring of physiological signals induced by respiration and heartbeat. To detect the tiny physiological movements of the chest or other parts of the torso, a Mulitple-Input Multiple-Output (MIMO) radar is used. The spatially distributed transmitters and receivers are able to detect the chest surface movements of one or multiple persons in a room. Due to several bistatic measurements at the same time a robust detection and measuring of the breathing and heartbeat rate is possible. Using an appropriate geometrical configuration of the sensors even a localization of the person is feasible.

  7. Contact Us about NREL | NREL

    Science.gov Websites

    Contact Us about NREL Contact Us about NREL Find mailing addresses, phone numbers, and contact -2157 202-488-2200 Phone Phone Numbers View a list of important phone numbers. Address book Contact a Staff Member at NREL Our searchable staff directory has contact information for staff. Questions

  8. Is email a reliable means of contacting authors of previously published papers? A study of the Emergency Medicine Journal for 2001.

    PubMed

    O'Leary, F

    2003-07-01

    To determine whether it is possible to contact authors of previously published papers via email. A cross sectional study of the Emergency Medicine Journal for 2001. 118 articles were included in the study. The response rate from those with valid email addresses was 73%. There was no statistical difference between the type of email address used and the address being invalid (p=0.392) or between the type of article and the likelihood of a reply (p=0.197). More responses were obtained from work addresses when compared with Hotmail addresses (86% v 57%, p=0.02). Email is a valid means of contacting authors of previously published articles, particularly within the emergency medicine specialty. A work based email address may be a more valid means of contact than a Hotmail address.

  9. Distinct Effects of Abelson Kinase Mutations on Myocytes and Neurons in Dissociated Drosophila Embryonic Cultures: Mimicking of High Temperature

    PubMed Central

    Liu, Lijuan; Wu, Chun-Fang

    2014-01-01

    Abelson tyrosine kinase (Abl) is known to regulate axon guidance, muscle development, and cell-cell interaction in vivo. The Drosophila primary culture system offers advantages in exploring the cellular mechanisms mediated by Abl with utilizing various experimental manipulations. Here we demonstrate that single-embryo cultures exhibit stage-dependent characteristics of cellular differentiation and developmental progression in neurons and myocytes, as well as nerve-muscle contacts. In particular, muscle development critically depends on the stage of dissociated embryos. In wild-type (WT) cultures derived from embryos before stage 12, muscle cells remained within cell clusters and were rarely detected. Interestingly, abundant myocytes were spotted in Abl mutant cultures, exhibiting enhanced myocyte movement and fusion, as well as neuron-muscle contacts even in cultures dissociated from younger, stage 10 embryos. Notably, Abl myocytes frequently displayed well-expanded lamellipodia. Conversely, Abl neurons were characterized with fewer large veil-like lamellipodia, but instead had increased numbers of filopodia and darker nodes along neurites. These distinct phenotypes were equally evident in both homo- and hetero-zygous cultures (Abl/Abl vs. Abl/+) of different alleles (Abl1 and Abl4) indicating dominant mutational effects. Strikingly, in WT cultures derived from stage 10 embryos, high temperature (HT) incubation promoted muscle migration and fusion, partially mimicking the advanced muscle development typical of Abl cultures. However, HT enhanced neuronal growth with increased numbers of enlarged lamellipodia, distinct from the characteristic Abl neuronal morphology. Intriguingly, HT incubation also promoted Abl lamellipodia expansion, with a much greater effect on nerve cells than muscle. Our results suggest that Abl is an essential regulator for myocyte and neuron development and that high-temperature incubation partially mimics the faster muscle development typical of Abl cultures. Despite the extensive alterations by Abl mutations, we observed myocyte fusion events and nerve-muscle contact formation between WT and Abl cells in mixed WT and Abl cultures derived from labeled embryos. PMID:24466097

  10. Rescore protein-protein docked ensembles with an interface contact statistics.

    PubMed

    Mezei, Mihaly

    2017-02-01

    The recently developed statistical measure for the type of residue-residue contact at protein complex interfaces, based on a parameter-free definition of contact, has been used to define a contact score that is correlated with the likelihood of correctness of a proposed complex structure. Comparing the proposed contact scores on the native structure and on a set of model structures the proposed measure was shown to generally favor the native structure but in itself was not able to reliably score the native structure to be the best. Adjusting the scores of redocking experiments with the contact score showed that the adjusted score was able to move up the ranking of the native-like structure among the proposed complexes when the native-like was not ranked the best by the respective program. Tests on docking of unbound proteins compared the contact scores of the complexes with the contact score of the crystal structure again showing the tendency of the contact score to favor native-like conformations. The possibility of using the contact score to improve the determination of biological dimers in a crystal structure was also explored. Proteins 2017; 85:235-241. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  11. 75 FR 43819 - Clarification of Grace Period for Encryption Registration Requirement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-27

    ... published on June 25, 2010. In addition, this rule corrects the e-mail address for the public contact... CONTACT: Sharron Cook, Regulatory Policy Division, e-mail [email protected] , telephone (202) 482-2440... in the FOR FURTHER INFORMATION CONTACT section of the preamble of the rule. The correct address for...

  12. Eye Wear

    MedlinePlus

    ... are Sunglasses Safety goggles Glasses (also called eyeglasses) Contact lenses If you need corrective lenses, you may be able to choose between contacts or glasses. Either usually requires a prescription. Almost ...

  13. Gadolinium-Based GaN for Neutron Detection with Gamma Discrimination

    DTIC Science & Technology

    2016-06-01

    spectroscopy system: 1, Earth ground; 2, Shielding and vacuum chamber; 3, Probe station; 4, Ohmic contact; 5, Schottky Contact; 6, BNC cable; 7...NUMBER 6. AUTHOR( S ) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) 8...PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING / MONITORING AGENCY NAME( S ) AND ADDRESS(ES) 10. SPONSOR

  14. 76 FR 22681 - Defense Logistics Agency (DLA) Address Directory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-22

    ... FOIA/Privacy Points of Contact are found at: http://www.dla.mil/foia-privacy/foia_poc.aspx . FOR FURTHER INFORMATION CONTACT: Ms. Jody Sinkler, 703-767-5045. SUPPLEMENTARY INFORMATION: DLA Address...

  15. Non-Contact Laser Based Ultrasound Evaluation of Canned Foods

    NASA Astrophysics Data System (ADS)

    Shelton, David

    2005-03-01

    Laser-Based Ultrasound detection was used to measure the velocity of compression waves transmitted through canned foods. Condensed broth, canned pasta, and non-condensed soup were evaluated in these experiments. Homodyne adaptive optics resulted in measurements that were more accurate than the traditional heterodyne method, as well as yielding a 10 dB gain in signal to noise. A-Scans measured the velocity of ultrasound sent through the center of the can and were able to distinguish the quantity of food stuff in its path, as well as distinguish between meat and potato. B-Scans investigated the heterogeneity of the sample’s contents. The evaluation of canned foods was completely non-contact and would be suitable for continuous monitoring in production. These results were verified by conducting the same experiments with a contact piezo transducer. Although the contact method yields a higher signal to noise ratio than the non-contact method, Laser-Based Ultrasound was able to detect surface waves the contact transducer could not.

  16. 76 FR 23341 - Sunshine Federal Register Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-26

    ...-415-1711) This meeting will be webcast live at the Web address-- http://www.nrc.gov . Week of May 2... Meeting); (Contact: Robert Kahler, 301-415-7528) This meeting will be webcast live at the Web address... Meeting); (Contact: Nathan Sanfilippo, 301-415-3951) This meeting will be webcast live at the Web address...

  17. Contact Inhibition: Also a Control for Cell Proliferation in Unicellular Algae?

    PubMed

    Costas, E; Aguilera, A; Gonzalez-Gil, S; López-Rodas, V

    1993-02-01

    According to traditional views, the proliferation of unicellular algae is controlled primarily by environmental conditions. But as in mammalian cells, other biological mechanisms, such as growth factors, cellular aging, and contact inhibition, might also control algal proliferation. Here we ask whether contact inhibition regulates growth in several species of unicellular algae as it does in mammalian cells. Laboratory cultures of the dinoflagellate Prorocentrum lima (Ehrenberg) Dodge show contact inhibition at low cell density, so this would be an autocontrol mechanism of cell proliferation that could also act in natural populations of P. lima. But, Synechocystis spp., Phaeodactylum tricornutum (Bohlin), Skeletonema costatum (Greville), and Tetraselmis spp. do not exhibit contact inhibition in laboratory cultures because they are able to grow at high cellular density. Apparently their growth is limited by nutrient depletion or catabolite accumulation instead of contact inhibition. Spirogyra insignis (Hassall) Kutz, Prorocentrum triestinum Schiller, and Alexandrium tamarense (Halim) Balech show a complex response, as they are able to grow in both low and high cell density medium. These results suggest that contact inhibition is more adaptative in benthic unicellular algae.

  18. Energy-Consistent Multiscale Algorithms for Granular Flows

    DTIC Science & Technology

    2014-08-07

    Respondents should be aware that notwithstanding any other provision of law, no person shall be subject to any penalty for failing to comply with a collection...not been able to be captured comprehensively in models. The consequences of these advancements are broad and deep. The GEM method has revolutionized...the algorithm to detect contact needs to be redesign to be able to detect contact points, even in non-convex surfaces. To achieve this, we developed

  19. U.S.-China Military Contacts: Issues for Congress

    DTIC Science & Technology

    2008-02-01

    Military Contacts: Issues for Congress 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) 5d. PROJECT NUMBER 5e. TASK...NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) Congressional Research Service,The Library of Congress,101...Independence Ave, SE,Washington,DC,20540-7500 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME( S ) AND ADDRESS(ES) 10. SPONSOR

  20. U.S.-China Military Contacts: Issues for Congress

    DTIC Science & Technology

    2007-12-12

    Military Contacts: Issues for Congress 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) 5d. PROJECT NUMBER 5e. TASK...NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) Congressional Research Center,The Library of Congress,101...Independence Ave, SE,Washington,DC,20540-7500 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME( S ) AND ADDRESS(ES) 10. SPONSOR

  1. 30 CFR 204.205 - How do I obtain accounting and auditing relief?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., address, phone number, and contact name; and (ii) The specific MMS lease number and agreement number, if... contain: (i) Your company name, MMS-assigned payor code, address, phone number, and contact name; (ii) The...

  2. Growth and Migration Plan for Data Insight

    DTIC Science & Technology

    2004-12-13

    exceed 30 users. The group of users must select one person to be the technical point of contact (TPOC). All technical and business questions shall...CONTACT (TPOC) INFORMATION Name: Title: Site: Address: City: State: Zip Code: E-mail address: Business phone number: Business fax

  3. Preliminary evaluation of hermetic JT/LJT/R P connector socket contact design

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Baca, J.R.F.

    1991-10-01

    This report presents a precursory examination of a number of issues pertaining to socket contacts in hermetic connectors. The principal issues addressed are high-contact resistance and contact chatter (circuit discontinuities). Efforts examining the characteristics of the existing socket contact design, the possibility of connector/contact rework, quick-fix solutions, and contact redesigns are summarized.

  4. Physical processes in wheel-rail contact and its implications on vehicle-track interaction

    NASA Astrophysics Data System (ADS)

    Six, K.; Meierhofer, A.; Müller, G.; Dietmaier, P.

    2015-05-01

    Friction within the wheel-rail contact highly influences all aspects of vehicle-track interaction. Models describing this frictional behaviour are of high relevance, for example, for reliable predictions on drive train dynamics. It has been shown by experiments, that the friction at a certain position on rail is not describable by only one number for the coefficient of friction. Beside the contact conditions (existence of liquids, solid third bodies, etc.) the vehicle speed, normal loading and contact geometry are further influencing factors. State-of-the-art models are not able to account for this sufficiently. Thus, an Extended-Creep-Force-Model was developed taking into account effects from third body layers. This model is able to describe all considered effects. In this way, a significant improvement of the prediction quality with respect to all aspects of vehicle-track interaction is expected.

  5. 78 FR 21846 - Approval and Promulgation of State Plans for Designated Facilities and Pollutants: Connecticut...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-12

    ... contact information unless you provide it in the body of your comment. If you send an email comment... Internet. If you submit an electronic comment, EPA recommends that you include your name and other contact... comment due to technical difficulties and cannot contact you for clarification, EPA may not be able to...

  6. 77 FR 13627 - Notice of Inventory Completion: History Colorado, Denver, CO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-07

    ...: History Colorado, Denver, CO AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: History... funerary objects may contact History Colorado. Disposition of the human remains and associated funerary... contact History Colorado at the address below by April 6, 2012. ADDRESSES: Sheila Goff, NAGPRA Liaison...

  7. 78 FR 49527 - Agency Information Collection Activities; Submission for Office of Management and Budget Review...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-14

    ...: Submitter type, company name, address, country, company headquarters Dun and Bradstreet number, and company headquarters Facility Establishment Identifier number; Submitter point of contact: Contact name, title... and signature of submitter including name, company name, address, position title, email, telephone...

  8. 19 CFR 142.42 - Application for Line Release processing.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Company Information: name, address, city, state, contact person, phone number of contact person, and... identification number of the shipper or manufacturer. (f) Importer information (if importer is different than filer): Name, address, city, state and country, zip code, importer number, bond number, and surety code...

  9. 19 CFR 142.42 - Application for Line Release processing.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Company Information: name, address, city, state, contact person, phone number of contact person, and... identification number of the shipper or manufacturer. (f) Importer information (if importer is different than filer): Name, address, city, state and country, zip code, importer number, bond number, and surety code...

  10. 19 CFR 142.42 - Application for Line Release processing.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Company Information: name, address, city, state, contact person, phone number of contact person, and... identification number of the shipper or manufacturer. (f) Importer information (if importer is different than filer): Name, address, city, state and country, zip code, importer number, bond number, and surety code...

  11. 19 CFR 142.42 - Application for Line Release processing.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Company Information: name, address, city, state, contact person, phone number of contact person, and... identification number of the shipper or manufacturer. (f) Importer information (if importer is different than filer): Name, address, city, state and country, zip code, importer number, bond number, and surety code...

  12. 75 FR 13284 - Pesticide Program Dialogue Committee; Request for Nominations to the Pesticide Program Dialogue...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-19

    ... racial and ethnic groups. Vacancies are expected to be filled by late spring 2010. Additional sources may... Fehrenbach at the address listed under FOR FURTHER INFORMATION CONTACT. FOR FURTHER INFORMATION CONTACT...; e-mail address: [email protected] . SUPPLEMENTARY INFORMATION: I. General Information A...

  13. 75 FR 12583 - Sunshine Act; Meeting Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-16

    ... Commission and the Nuclear Regulatory Commission on Grid Reliability (Public Meeting). (Contact: Kenn Miller, 301-415-3152). This meeting will be webcast live at the Web address-- http://www.nrc.gov . Week of...) (Contact: Jose Ibarra, 301-415-2581). This meeting will be webcast live at the Web address-- http://www.nrc...

  14. 77 FR 61548 - Airworthiness Directives; The Boeing Company Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-10

    .... Comments will be available in the AD docket shortly after receipt. FOR FURTHER INFORMATION CONTACT: Ray Mei..., views, or arguments about this proposal. Send your comments to an address listed under the ADDRESSES... office. (j) Related Information (1) For more information about this AD, contact Ray Mei, Aerospace...

  15. 43 CFR 3809.301 - Where do I file my notice and what information must I include in it?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... within 30 calendar days of any change of operator or corporate point of contact, or of the mailing address of the operator or corporate point of contact. ... include the following information: (1) Operator Information. The name, mailing address, phone number...

  16. 43 CFR 3809.301 - Where do I file my notice and what information must I include in it?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... within 30 calendar days of any change of operator or corporate point of contact, or of the mailing address of the operator or corporate point of contact. ... include the following information: (1) Operator Information. The name, mailing address, phone number...

  17. 43 CFR 3809.301 - Where do I file my notice and what information must I include in it?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... within 30 calendar days of any change of operator or corporate point of contact, or of the mailing address of the operator or corporate point of contact. ... include the following information: (1) Operator Information. The name, mailing address, phone number...

  18. 43 CFR 3809.301 - Where do I file my notice and what information must I include in it?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... within 30 calendar days of any change of operator or corporate point of contact, or of the mailing address of the operator or corporate point of contact. ... include the following information: (1) Operator Information. The name, mailing address, phone number...

  19. 77 FR 75153 - Notice of Receipt of Pesticide Products; Registration Applications To Register New Uses

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-19

    ..., millet, strawberry, sugarcane, and tree nuts. Contact: Olga Odiott, (703) 308-9369, email address: odiott... vegetables, cucurbit vegetables, grapes, leafy vegetables (except Brassica), root vegetables, strawberry, and..., strawberry, sugarcane, and tree nuts. Contact: Olga Odiott, (703) 308-9369, email address: [email protected

  20. Why does it run in families? Explaining family similarity in help-seeking behaviour by shared circumstances, socialisation and selection.

    PubMed

    Cardol, Mieke; Groenewegen, Peter P; Spreeuwenberg, Peter; Van Dijk, Liset; Van Den Bosch, Wil J H M; De Bakker, Dinny H

    2006-08-01

    Why do contact frequencies with general practice of family members resemble each other? Many aspects related to the clustering of health-care utilisation within families have been studied, but the underlying mechanisms have not been addressed. This article considers whether family similarity in contact frequency with general practice can be explained as (a) a result of shared circumstances, (b) through socialisation, and (c) through homogeneity of background characteristics. Data from the second Dutch national survey of general practice were used to test these mechanisms empirically. This survey recorded all consultations in 2001 for 104 general practices in the Netherlands, serving 385,461 patients. Information about socio-demographic characteristics was collected by means of a patient survey. In a random sample, an extended health interview took place (n=12,699). Overall, we were able to show that having determinants in common through socialisation and shared circumstances can explain similarity in contact frequencies within families, but not all hypotheses could be confirmed. In specific terms, this study shows that resemblances in contact frequencies within families can be best explained by spending more time together (socialisation) and parents and children consulting a general practitioner simultaneously (circumstances of the moment). For general practitioners, the mechanisms identified can serve as a framework for a family case history. The importance of the mechanism of socialisation in explaining similarities in help-seeking behaviour between family members points to the significance of knowledge and health beliefs underlying consultation behaviour. An integrated framework including these aspects can help to better explain health behaviour.

  1. Robust and Opportunistic Autonomous Science for a Potential Titan Aerobot

    NASA Technical Reports Server (NTRS)

    Gaines, Daniel M.; Estlin, Tara; Schaffer, Steve; Castano, Rebecca; Elfes, Alberto

    2010-01-01

    We are developing onboard planning and execution technologies to provide robust and opportunistic mission operations for a potential Titan aerobot. Aerobot have the potential for collecting a vast amount of high priority science data. However, to be effective, an aerobot must address several challenges including communication constraints, extended periods without contact with Earth, uncertain and changing environmental conditions, maneuverability constraints and potentially short-lived science opportunities. We are developing the AerOASIS system to develop and test technology to support autonomous science operations for a potential Titan Aerobot. The planning and execution component of AerOASIS is able to generate mission operations plans that achieve science and engineering objectives while respecting mission and resource constraints as well as adapting the plan to respond to new science opportunities. Our technology leverages prior work on the OASIS system for autonomous rover exploration. In this paper we describe how the OASIS planning component was adapted to address the unique challenges of a Titan Aerobot and we describe a field demonstration of the system with the JPL prototype aerobot.

  2. Low nonalloyed Ohmic contact resistance to nitride high electron mobility transistors using N-face growth

    NASA Astrophysics Data System (ADS)

    Wong, Man Hoi; Pei, Yi; Palacios, Tomás; Shen, Likun; Chakraborty, Arpan; McCarthy, Lee S.; Keller, Stacia; DenBaars, Steven P.; Speck, James S.; Mishra, Umesh K.

    2007-12-01

    Nonalloyed Ohmic contacts on Ga-face n+-GaN/AlGaN/GaN high electron mobility transistor (HEMT) structures typically have significant contact resistance to the two-dimensional electron gas (2DEG) due to the AlGaN barrier. By growing the HEMT structure inverted on the N-face, electrons from the contacts were able to access the 2DEG without going through an AlGaN layer. A low contact resistance of 0.16Ωmm and specific contact resistivity of 5.5×10-7Ωcm2 were achieved without contact annealing on the inverted HEMT structure.

  3. 77 FR 27099 - Sunshine Federal Register Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-08

    ... Actions, (Public Meeting), (Contact: Jessie Quichocho, 301-415-0209). This meeting will be webcast live at... meeting will be webcast live at the Web address: www.nrc.gov . Week of June 4, 2012--Tentative Thursday...) (Contact: Tanny Santos, 301-415-7270). This meeting will be webcast live at the Web address: www.nrc.gov...

  4. 77 FR 20611 - Notice of Intent To Request an Extension and Revision of a Currently Approved Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-05

    ... Service's (ARS) intention to seek approval to collect information in support of research and related... consideration. ADDRESSES: Address all comments concerning this notice to Jill Philpot, ARS Webmaster, 5601 Sunnyside Avenue, Beltsville, MD 20705. FOR FURTHER INFORMATION CONTACT: Contact Jill Philpot, ARS Webmaster...

  5. 75 FR 16445 - Defense Transportation Regulation, Part IV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-01

    ... encompass procedures for Non-temporary Storage (NTS), Domestic Small Shipments (dS2, formerly DPM), Domestic... or before 1 June 2010. ADDRESSES: Do not submit comments directly to the point of contact under FOR FURTHER INFORMATION CONTACT or mail your comments to any address other than what is shown below. Doing so...

  6. 30 CFR 1204.205 - How do I obtain accounting and auditing relief?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... code, address, phone number, and contact name; and (ii) The specific ONRR lease number and agreement number, if applicable. (2) You may file a single notification for multiple marginal properties. (b) To... request must contain: (i) Your company name, ONRR-assigned payor code, address, phone number, and contact...

  7. 30 CFR 1204.205 - How do I obtain accounting and auditing relief?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... code, address, phone number, and contact name; and (ii) The specific ONRR lease number and agreement number, if applicable. (2) You may file a single notification for multiple marginal properties. (b) To... request must contain: (i) Your company name, ONRR-assigned payor code, address, phone number, and contact...

  8. 30 CFR 1204.205 - How do I obtain accounting and auditing relief?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... code, address, phone number, and contact name; and (ii) The specific ONRR lease number and agreement number, if applicable. (2) You may file a single notification for multiple marginal properties. (b) To... request must contain: (i) Your company name, ONRR-assigned payor code, address, phone number, and contact...

  9. Migration histories of multidrug-resistant tuberculosis patients from the Thailand-Myanmar border, 2012-2014.

    PubMed

    Thi, S S; Parker, D M; Swe, L L; Pukrittayakamee, S; Ling, C L; Amornpaisarnloet, K; Vincenti-Delmas, M; Nosten, F H

    2017-07-01

    Multidrug-resistant tuberculosis (MDR-TB) is a growing public health threat in South-East Asia. TB is typically a disease of poverty and can be spread by infectious humans who migrate from one region to another. We interviewed 20 MDR-TB patients on the Thailand-Myanmar border with regard to their migration histories. Migration origins and destinations were mapped. All but one participant had a history of migration, and maps of migration ranges revealed wide geographic dispersal. Most described living and work conditions that could contribute to the spread of drug-resistant TB, including numerous contacts and crowded living quarters. Our results show that at least some migrant workers in the region carry MDR-TB, and indicate that this subgroup of the population is important with regard to the transmission of MDR-TB throughout the region. Migrants in this region come into contact with high numbers of people and may be able to spread the disease across wide geographic ranges. Access to diagnosis and treatment and socio-economic development are at least as important as any TB control measures, meaning that innovative and bold approaches that extend across international borders are needed to address these problems.

  10. Printing medicines as orodispersible dosage forms: Effect of substrate on the printed micro-structure.

    PubMed

    Planchette, C; Pichler, H; Wimmer-Teubenbacher, M; Gruber, M; Gruber-Woelfler, H; Mohr, S; Tetyczka, C; Hsiao, W-K; Paudel, A; Roblegg, E; Khinast, J

    2016-07-25

    We present our recent advancements in developing a viable manufacturing process for printed medicine. Our approach involves using a non-contact printing system that incorporates both piezoelectric- and solenoid valve-based inkjet printing technologies, to deliver both active and inactive pharmaceutical materials onto medical-graded orodispersible films. By using two complimentary inkjet technologies, we were able to dispense an extensive range of fluids, from aqueous drug solutions to viscous polymer coating materials. Essentially, we demonstrate printing of a wide range of formulations for patient-ready, orodispersible drug dosage forms, without the risk of drug degradation by ink heating and of substrate damages (by contact printing). In addition, our printing process has been optimized to ensure that the drug doses can be loaded onto the orally dissolvable films without introducing defects, such as holes or tears, while retaining a smooth surface texture that promotes patient adherence and allows for uniform post-coatings. Results show that our platform technology can address key issues in manufacturing orodispersible drug dosage forms and bring us closer to delivering personalized and precision medicine to targeted patient populations. Copyright © 2015 Elsevier B.V. All rights reserved.

  11. 78 FR 46309 - Rules of Administrative Finality

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-31

    ... you a tracking number to confirm your submission. You will not be able to view your comment...://www.regulations.gov , or in person, during regular business hours, by arranging with the contact person identified below. FOR FURTHER INFORMATION CONTACT: Zeenat Kolia, Office of Income Security...

  12. A non-Hertzian method for solving wheel-rail normal contact problem taking into account the effect of yaw

    NASA Astrophysics Data System (ADS)

    Liu, Binbin; Bruni, Stefano; Vollebregt, Edwin

    2016-09-01

    A novel approach is proposed in this paper to deal with non-Hertzian normal contact in wheel-rail interface, extending the widely used Kik-Piotrowski method. The new approach is able to consider the effect of the yaw angle of the wheelset against the rail on the shape of the contact patch and on pressure distribution. Furthermore, the method considers the variation of profile curvature across the contact patch, enhancing the correspondence to CONTACT for highly non-Hertzian contact conditions. The simulation results show that the proposed method can provide more accurate estimation than the original algorithm compared to Kalker's CONTACT, and that the influence of yaw on the contact results is significant under certain circumstances.

  13. Sliding mode-based lateral vehicle dynamics control using tyre force measurements

    NASA Astrophysics Data System (ADS)

    Kunnappillil Madhusudhanan, Anil; Corno, Matteo; Holweg, Edward

    2015-11-01

    In this work, a lateral vehicle dynamics control based on tyre force measurements is proposed. Most of the lateral vehicle dynamics control schemes are based on yaw rate whereas tyre forces are the most important variables in vehicle dynamics as tyres are the only contact points between the vehicle and road. In the proposed method, active front steering is employed to uniformly distribute the required lateral force among the front left and right tyres. The force distribution is quantified through the tyre utilisation coefficients. In order to address the nonlinearities and uncertainties of the vehicle model, a gain scheduling sliding-mode control technique is used. In addition to stabilising the lateral dynamics, the proposed controller is able to maintain maximum lateral acceleration. The proposed method is tested and validated on a multi-body vehicle simulator.

  14. Functional Rehabilitation With a Foot Plate Modification for Circular External Fixation

    DTIC Science & Technology

    2013-04-05

    5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) United States Army Institute of...Surgical Research, JBSA Fort Sam Houston, TX 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR...patient was able to perform . Results: Eleven patients were identified. All patients were treated by the same physical therapist. All 11 patients were able

  15. National directory of space grant contacts

    NASA Technical Reports Server (NTRS)

    1995-01-01

    In this directory of space grant contacts of the NASA Space Grant College and Fellowship Program a listing of participating universities and other institutions are shown from all 50 states and from the District of Columbia and Puerto Rico. These 52 Space Grant State consortia currently consist of 395 institutions of higher learning, 66 industry affiliates, 26 state/local government offices, 40 nonprofit organizations, and 25 other educational entities. This directory is organized alphabetically by state and the contacts, addresses, phone numbers, and internet email addresses (where available) are included.

  16. 75 FR 59674 - Negotiated Rulemaking Committee on Designation of Medically Underserved Populations and Health...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-28

    ... CONTACT: For more information, please contact Nicole Patterson, Office of Shortage Designation, Bureau of... written comments to the Committee should be sent to Nicole Patterson at the contact address above at least...

  17. EpiTools, A software suite for presurgical brain mapping in epilepsy: Intracerebral EEG.

    PubMed

    Medina Villalon, S; Paz, R; Roehri, N; Lagarde, S; Pizzo, F; Colombet, B; Bartolomei, F; Carron, R; Bénar, C-G

    2018-06-01

    In pharmacoresistant epilepsy, exploration with depth electrodes can be needed to precisely define the epileptogenic zone. Accurate location of these electrodes is thus essential for the interpretation of Stereotaxic EEG (SEEG) signals. As SEEG analysis increasingly relies on signal processing, it is crucial to make a link between these results and patient's anatomy. Our aims were thus to develop a suite of software tools, called "EpiTools", able to i) precisely and automatically localize the position of each SEEG contact and ii) display the results of signal analysis in each patient's anatomy. The first tool, GARDEL (GUI for Automatic Registration and Depth Electrode Localization), is able to automatically localize SEEG contacts and to label each contact according to a pre-specified nomenclature (for instance that of FreeSurfer or MarsAtlas). The second tool, 3Dviewer, enables to visualize in the 3D anatomy of the patient the origin of signal processing results such as rate of biomarkers, connectivity graphs or Epileptogenicity Index. GARDEL was validated in 30 patients by clinicians and proved to be highly reliable to determine within the patient's individual anatomy the actual location of contacts. GARDEL is a fully automatic electrode localization tool needing limited user interaction (only for electrode naming or contact correction). The 3Dviewer is able to read signal processing results and to display them in link with patient's anatomy. EpiTools can help speeding up the interpretation of SEEG data and improving its precision. Copyright © 2018 Elsevier B.V. All rights reserved.

  18. Flexible integrated circuits and multifunctional electronics based on single atomic layers of MoS2 and graphene

    NASA Astrophysics Data System (ADS)

    Amani, Matin; Burke, Robert A.; Proie, Robert M.; Dubey, Madan

    2015-03-01

    Two-dimensional materials, such as graphene and its analogues, have been investigated by numerous researchers for high performance flexible and conformal electronic systems, because they offer the ultimate level of thickness scaling, atomically smooth surfaces and high crystalline quality. Here, we use layer-by-layer transfer of large area molybdenum disulphide (MoS2) and graphene grown by chemical vapor deposition (CVD) to demonstrate electronics on flexible polyimide (PI) substrates. On the same PI substrate, we are able to simultaneously fabricate MoS2 based logic, non-volatile memory cells with graphene floating gates, photo-detectors and MoS2 transistors with tunable source and drain contacts. We are also able to demonstrate that these flexible heterostructure devices have very high electronic performance, comparable to four point measurements taken on SiO2 substrates, with on/off ratios >107 and field effect mobilities as high as 16.4 cm2 V-1 s-1. Additionally, the heterojunctions show high optoelectronic sensitivity and were operated as photodetectors with responsivities over 30 A W-1. Through local gating of the individual graphene/MoS2 contacts, we are able to tune the contact resistance over the range of 322-1210 Ω mm for each contact, by modulating the graphene work function. This leads to devices with tunable and multifunctional performance that can be implemented in a conformable platform.

  19. Flexible integrated circuits and multifunctional electronics based on single atomic layers of MoS2 and graphene.

    PubMed

    Amani, Matin; Burke, Robert A; Proie, Robert M; Dubey, Madan

    2015-03-20

    Two-dimensional materials, such as graphene and its analogues, have been investigated by numerous researchers for high performance flexible and conformal electronic systems, because they offer the ultimate level of thickness scaling, atomically smooth surfaces and high crystalline quality. Here, we use layer-by-layer transfer of large area molybdenum disulphide (MoS2) and graphene grown by chemical vapor deposition (CVD) to demonstrate electronics on flexible polyimide (PI) substrates. On the same PI substrate, we are able to simultaneously fabricate MoS2 based logic, non-volatile memory cells with graphene floating gates, photo-detectors and MoS2 transistors with tunable source and drain contacts. We are also able to demonstrate that these flexible heterostructure devices have very high electronic performance, comparable to four point measurements taken on SiO2 substrates, with on/off ratios >10(7) and field effect mobilities as high as 16.4 cm(2) V(-1) s(-1). Additionally, the heterojunctions show high optoelectronic sensitivity and were operated as photodetectors with responsivities over 30 A W(-1). Through local gating of the individual graphene/MoS2 contacts, we are able to tune the contact resistance over the range of 322-1210 Ω mm for each contact, by modulating the graphene work function. This leads to devices with tunable and multifunctional performance that can be implemented in a conformable platform.

  20. Automatic address validation and health record review to identify homeless Social Security disability applicants.

    PubMed

    Erickson, Jennifer; Abbott, Kenneth; Susienka, Lucinda

    2018-06-01

    Homeless patients face a variety of obstacles in pursuit of basic social services. Acknowledging this, the Social Security Administration directs employees to prioritize homeless patients and handle their disability claims with special care. However, under existing manual processes for identification of homelessness, many homeless patients never receive the special service to which they are entitled. In this paper, we explore address validation and automatic annotation of electronic health records to improve identification of homeless patients. We developed a sample of claims containing medical records at the moment of arrival in a single office. Using address validation software, we reconciled patient addresses with public directories of homeless shelters, veterans' hospitals and clinics, and correctional facilities. Other tools annotated electronic health records. We trained random forests to identify homeless patients and validated each model with 10-fold cross validation. For our finished model, the area under the receiver operating characteristic curve was 0.942. The random forest improved sensitivity from 0.067 to 0.879 but decreased positive predictive value to 0.382. Presumed false positive classifications bore many characteristics of homelessness. Organizations could use these methods to prompt early collection of information necessary to avoid labor-intensive attempts to reestablish contact with homeless individuals. Annually, such methods could benefit tens of thousands of patients who are homeless, destitute, and in urgent need of assistance. We were able to identify many more homeless patients through a combination of automatic address validation and natural language processing of unstructured electronic health records. Copyright © 2018. Published by Elsevier Inc.

  1. Contact Lens-related Complications: A Review

    PubMed Central

    Alipour, Fateme; Khaheshi, Saeed; Soleimanzadeh, Mahya; Heidarzadeh, Somayeh; Heydarzadeh, Sepideh

    2017-01-01

    Contact lens-related problems are common and can result in severe sight-threatening complications or contact lens drop out if not addressed properly. We systematically reviewed the most important and the most common contact lens-related complications and their diagnosis, epidemiology, and management according to the literature published in the last 20 years. PMID:28540012

  2. 76 FR 75504 - Table Saw Blade Contact Injuries; Notice of Extension of Time for Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-02

    ... [Docket No. CPSC-2011-0074] Table Saw Blade Contact Injuries; Notice of Extension of Time for Comments... blade contact, regulatory alternatives, other possible means to address this risk, and other topics or... identifiers, contact information, or other personal information provided, to: http://www.regulations.gov . Do...

  3. Precision contact of the fingertip reduces postural sway of individuals with bilateral vestibular loss

    NASA Technical Reports Server (NTRS)

    Lackner, J. R.; DiZio, P.; Jeka, J.; Horak, F.; Krebs, D.; Rabin, E.

    1999-01-01

    Contact of the hand with a stationary surface attenuates postural sway in normal individuals even when the level of force applied is mechanically inadequate to dampen body motion. We studied whether subjects without vestibular function would be able to substitute contact cues from the hand for their lost labyrinthine function and be able to balance as well as normal subjects in the dark without finger contact. We also studied the relative contribution of sight of the test chamber to the two groups. Subjects attempted to maintain a tandem Romberg stance for 25 s under three levels of fingertip contact: no contact; light-touch contact, up to 1 N (approximately 100 g) force; and unrestricted contact force. Both eyes open and eyes closed conditions were evaluated. Without contact, none of the vestibular loss subjects could stand for more than a few seconds in the dark without falling; all the normals could. The vestibular loss subjects were significantly more stable in the dark with light touch of the index finger than the normal subjects in the dark without touch. They also swayed less in the dark with light touch than when permitted sight of the test chamber without touch, and less with sight and touch than just sight. The normal subjects swayed less in the dark with touch than without, and less with sight and touch than sight alone. These findings show that during quiet stance light touch of the index finger with a stationary surface can be as effective or even more so than vestibular function for minimizing postural sway.

  4. 76 FR 26333 - U.S. Department of State Advisory Committee on Private International Law (ACPIL); Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-06

    ... contact Tricia Smeltzer or Niesha Toms of the Department of State Legal Adviser's Office at [email protected] or Toms[email protected] and provide your name, affiliation, e-mail address, and mailing address... teleconferencing, please contact Tricia Smeltzer or Niesha Toms at 202-776-8420 to receive the conference call- in...

  5. 76 FR 46798 - FIFRA Scientific Advisory Panel; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-03

    ... convenience. If difficulties arise resulting in webcasting outages, the meeting will continue as planned... difficulties and cannot contact you for clarification, EPA may not be able to consider your comment. Electronic... FURTHER INFORMATION CONTACT: Fred Jenkins, Jr., DFO, Office of Science Coordination and Policy (7201M...

  6. 75 FR 56101 - FIFRA Scientific Advisory Panel; Notice of Rescheduled Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-15

    ... provided only for convenience. If difficulties arise resulting in webcasting outages, the meeting will... difficulties and cannot contact you for clarification, EPA may not be able to consider your comment. Electronic... FURTHER INFORMATION CONTACT: Sharlene Matten, DFO, Office of Science Coordination and Policy (7201M...

  7. 75 FR 79329 - Negotiated Rulemaking Committee on Designation of Medically Underserved Populations and Health...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... CONTACT: For more information, please contact Nicole Patterson, Office of Shortage Designation, Bureau of... Patterson at the contact address above at least 10 days prior to the meeting. The meetings will be open to...

  8. Biodegradable charged polyester-based vectors (BCPVs) as an efficient non-viral transfection nanoagent for gene knockdown of the BCR-ABL hybrid oncogene in a human chronic myeloid leukemia cell line

    NASA Astrophysics Data System (ADS)

    Yang, Chengbin; Panwar, Nishtha; Wang, Yucheng; Zhang, Butian; Liu, Maixian; Toh, Huiting; Yoon, Ho Sup; Tjin, Swee Chuan; Chong, Peter Han Joo; Law, Wing-Cheung; Chen, Chih-Kuang; Yong, Ken-Tye

    2016-04-01

    First-line therapy of chronic myelogenous leukemia (CML) has always involved the use of BCR-ABL tyrosine-kinase inhibitors which is associated with an abnormal chromosome called Philadelphia chromosome. Although the overall survival rate has been improved by the current therapeutic regime, the presence of resistance has resulted in limited efficacy. In this study, an RNA interference (RNAi)-based therapeutic regime is proposed with the aim to knockdown the BCR-ABL hybrid oncogene using small interfering RNA (siRNA). The siRNA transfection rates have usually been limited due to the declining contact probability among polyplexes and the non-adherent nature of leukemic cells. Our work aims at addressing this limitation by using a biodegradable charged polyester-based vector (BCPV) as a nanocarrier for the delivery of BCR-ABL-specific siRNA to the suspension culture of a K562 CML cell line. BCR-ABL siRNAs were encapsulated in the BCPVs by electrostatic force. Cell internalization was facilitated by the BCPV and assessed by confocal microscopy and flow cytometry. The regulation of the BCR-ABL level in K562 cells as a result of RNAi was analyzed by real-time polymerase chain reaction (RT-PCR). We observed that BCPV was able to form stable nanoplexes with siRNA molecules, even in the presence of fetal bovine serum (FBS), and successfully assisted in vitro siRNA transfection in the non-adherent K562 cells. As a consequence of downregulation of BCR-ABL, BCPV-siRNA nanoplexes inhibited cell proliferation and promoted cell apoptosis. All results were compared with a commercial transfection reagent, Lipofectamine2000™, which served as a positive control. More importantly, this class of non-viral vector exhibits biodegradable features and negligible cytotoxicity, thus providing a versatile platform to deliver siRNA to non-adherent leukemia cells with high transfection efficiency by effectively overcoming extra- and intra-cellular barriers. Due to the excellent in vitro transfection results from BCPV-siRNA, a newly developed biodegradable transfection agent, BCPV, is being probed for transfection performance in an animal model.

  9. Non-invasive pre-lens tear film assessment with high-speed videokeratoscopy.

    PubMed

    Llorens-Quintana, Clara; Mousavi, Maryam; Szczesna-Iskander, Dorota; Iskander, D Robert

    2018-02-01

    To evaluate the effect of two types of daily contact lenses (delefilcon A and omafilcon A) on the tear film and establish whether it is dependent on pre-corneal tear film characteristics using a new method to analyse high-speed videokeratoscopy recordings, as well as to determine the sensitivity of the method in differentiating between contact lens materials on eye. High-speed videokeratoscopy recordings were analysed using a custom made automated algorithm based on a fractal dimension approach that provides a set of parameters directly related to tear film stability. Fifty-four subjects participated in the study. Baseline measurements, in suppressed and natural blinking conditions, were taken before subjects were fitted with two different daily contact lenses and after four hours of contact lens wear. The method for analysing the stability of the tear film provides alternative parameters to the non-invasive break up time to assess the quality of the pre-corneal and pre-lens tear film. Both contact lenses significantly decreased the quality of the tear film in suppressed and natural blinking conditions (p<0.001). The utilised method was able to distinguish between contact lens materials on eye in suppressed blinking conditions. The pre-corneal tear film characteristics were not correlated with the decrease in pre-lens tear film quality. High-speed videokeratoscopy equipped with an automated method to analyse the dynamics of the tear film is able to distinguish between contact lens materials in vivo. Incorporating the assessment of pre-lens tear film to the clinical practice could aid improving contact lens fitting and understand contact lens comfort. Copyright © 2017 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.

  10. Spin analysis of concentrated traction contacts

    NASA Technical Reports Server (NTRS)

    Loewenthal, S. H.

    1983-01-01

    Spin, the result of a mismatch in contact radii on either side of the point of rolling, has a detrimental effect on traction contact performance. It occurs in concentrated contacts having conical or contoured rolling elements, such as those in traction drives or angular contact bearings, and is responsible for an increase in contact heating and power loss. The kinematics of spin producing contact geometries and the subsequent effect on traction and power loss are investigated. The influence of lubricant traction characteristics and contact geometries that minimize spin are also addressed.

  11. 16 CFR 315.1 - Scope of regulations in this part.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... CONTACT LENS RULE § 315.1 Scope of regulations in this part. This part, which shall be called the “Contact Lens Rule,” implements the Fairness to Contact Lens Consumers Act, codified at 15 U.S.C. 7601-7610, which requires that rules be issued to address the release, verification, and sale of contact lens...

  12. Study of mechanical behavior of AFM silicon tips under mechanical load

    NASA Astrophysics Data System (ADS)

    Kopycinska-Mueller, M.; Gluch, J.; Köhler, B.

    2016-11-01

    In this paper we address critical issues concerning calibration of AFM based methods used for nanoscale mechanical characterization of materials. It has been shown that calibration approaches based on macroscopic models for contact mechanics may yield excellent results in terms of the indentation modulus of the sample, but fail to provide a comprehensive and actual information concerning the tip-sample contact radius or the mechanical properties of the tip. Explanations for the severely reduced indentation modulus of the tip included the inadequacies of the models used for calculations of the tip-sample contact stiffness, discrepancies in the actual and ideal shape of the tip, presence of the amorphous silicon phase within the silicon tip, as well as negligence of the actual size of the stress field created in the tip during elastic interactions. To clarify these issues, we investigated the influence of the mechanical load applied to four AFM silicon tips on their crystalline state by exposing them to systematically increasing loads, evaluating the character of the tip-sample interactions via the load-unload stiffness curves, and assessing the state of the tips from HR-TEM images. The results presented in this paper were obtained in a series of relatively simple and basic atomic force acoustic microscopy (AFAM) experiments. The novel combination of TEM imaging of the AFM tips with the analysis of the load-unload stiffness curves gave us a detailed insight into their mechanical behavior under load conditions. We were able to identify the limits for the elastic interactions, as well as the hallmarks for phase transformation and dislocation formation and movement. The comparison of the physical dimensions of the AFM tips, geometry parameters determined from the values of the contact stiffness, and the information on the crystalline state of the tips allowed us a better understanding of the nanoscale contact.

  13. 76 FR 54185 - Fenamiphos; Proposed Data Call-In Order for Pesticide Tolerance

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-31

    ... electronic comment, EPA recommends that you include your name and other contact information in the body of... difficulties and cannot contact you for clarification, EPA may not be able to consider your comment. Electronic... available docket materials are available either in the electronic docket at http://www.regulations.gov , or...

  14. 45 CFR 46.502 - What information must be provided when registering an IRB?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...) of the institution or organization operating the IRB(s); and the name, mailing address, phone number..., phone number, facsimile number, and electronic mail address of the contact person providing the... IRB's mailing address, street address (if different from the mailing address), phone number, facsimile...

  15. 45 CFR 46.502 - What information must be provided when registering an IRB?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ...) of the institution or organization operating the IRB(s); and the name, mailing address, phone number..., phone number, facsimile number, and electronic mail address of the contact person providing the... IRB's mailing address, street address (if different from the mailing address), phone number, facsimile...

  16. 45 CFR 46.502 - What information must be provided when registering an IRB?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ...) of the institution or organization operating the IRB(s); and the name, mailing address, phone number..., phone number, facsimile number, and electronic mail address of the contact person providing the... IRB's mailing address, street address (if different from the mailing address), phone number, facsimile...

  17. 45 CFR 46.502 - What information must be provided when registering an IRB?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ...) of the institution or organization operating the IRB(s); and the name, mailing address, phone number..., phone number, facsimile number, and electronic mail address of the contact person providing the... IRB's mailing address, street address (if different from the mailing address), phone number, facsimile...

  18. 45 CFR 46.502 - What information must be provided when registering an IRB?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ...) of the institution or organization operating the IRB(s); and the name, mailing address, phone number..., phone number, facsimile number, and electronic mail address of the contact person providing the... IRB's mailing address, street address (if different from the mailing address), phone number, facsimile...

  19. Innovation Inspired by Nature: Capabilities, Potentials and Challenges

    NASA Technical Reports Server (NTRS)

    Bar-Cohen, Yoseph

    2012-01-01

    Through evolution, nature came up with many effective solutions to its challenges and continually improving them. By mimicking, coping and being inspired, humans have been using Nature's solutions to address their own challenges. In recent years, the implementation of nature's capabilities has intensified with our growing understanding of the various biological and nastic mechanisms and processes. Successes include even the making of humanlike robots that perform such lifelike tasks as walking, talking, making eye-contact, interpreting speech and facial expressions, as well as many other humanlike functions. Generally, once humans are able to implement a function then, thru rapid advances in technology, capabilities are developed that can significantly exceed the original source of inspiration in Nature. Examples include flight where there is no species that can fly as high, carry so much mass, has so large dimensions and fly so fast, and operate at as such extreme conditions as our aircraft and other aerospace systems. However, using the capabilities of today's technology, there are many challenges that are not feasible to address in mimicking characteristics of species and plants. In this manuscript, state-of-the-art of biomimetic capabilities, potentials and challenges are reviewed.

  20. Relocating from out-of-area treatments: service users' perspective.

    PubMed

    Rambarran, D D

    2013-10-01

    Asylum closures over recent decades resulted in mental health services being increasingly sited in the community. However, under provision of highly supported accommodation led to service users being placed away from their local area in 'out-of-area treatments' (OATs). OATs have raised major concerns in relation to enabling service users' recovery, owing to limitations in promoting autonomy, social dislocation and costs. In 2004, an OATs project was set up in a London Borough to address these concerns. In the first 4 years, the project succeeded in relocating 22 service users to less restrictive environments locally. This study aims to explore the outcome of relocation from service users' perspective. A qualitative methodology was utilized. Semi-structured interviews were carried out with seven service users who relocated. All seven service users shared a strong aspiration for independent living but there was associated loneliness. Five welcomed increased contact with family and friends, but lacked social confidence, inhibiting social inclusion. Service users with long-term and consistent care managers were more able to address fears. Five out of seven service users concluded that relocation increased their autonomy thus enhanced their quality of life. © 2012 John Wiley & Sons Ltd.

  1. Development of an autonomous unmanned aerial system for atmospheric data collection and research

    NASA Astrophysics Data System (ADS)

    Lee, Andrew; Hanlon, David; Sakai, Ricardo; Morris, Vernon; Demoz, Belay; Gadsden, S. Andrew

    2016-05-01

    This paper addresses the use of unmanned aerial systems (UAS) to carry out atmospheric data collection and studies. An important area of research is the study of the chemistry and physics of Earth's planetary boundary layer (PBL). The PBL, also known as the atmospheric boundary layer (ABL), is the lowest part of the atmosphere and its behavior is directly influenced by its contact with the planetary surface. Sampling of the PBL is performed in a timely and periodic manner. Currently, sensors and uncontrollable balloons are used to obtain relevant data and information. This method is cumbersome and can be ineffective in obtaining consistent environmental data. This paper proposes the use of autonomous UAS' to study the atmosphere in an effort to improve the efficiency and accuracy of the sampling process. The UAS setup and design is provided, and preliminary data collection information is shared.

  2. How Fast is Collapse of Proteins During Folding?

    NASA Astrophysics Data System (ADS)

    Chahine, J.; Onuchic, J. N.; Socci, N. D.

    1998-03-01

    Recent experiments in fast folding proteins are now starting to address the question of how fast is collapse relative to the total folding time. Using minimalist models, we are able to investigate the way in which different scenarios of folding can arise depending on the interplay between the collapse order parameter and the order parameter sensitive to specific tertiary contacts. Most of our earlier studies have focused on the limit that collapse is very fast compared to the total folding time. In this work we focus on the opposite limit, i.e., at the folding temperature, collapse and folding occurs simultaneously. The folding mechanism becomes very different in this limit. Particularly, the non-specific collapse transition, that occurs at temperatures higher than the folding temperature for the fast collapse limit, now occurs between the folding and the glass temperature. We show how this transition can be identified and its consequences for the folding kinetics.

  3. Proposed Bak Stabilization Tennessee River, River Mile 466.2 - 466.5 Hamilton County, Tennessee

    DTIC Science & Technology

    2013-04-01

    Project Planning Branch EA Preparation Mitzy Schaney, Archaeologist Project Planning Branch Cultural Resources Preparation Ramune Morales, Project...addressed in our evaluation. Please contact Mitzy L. Schaney at (615) 736-2268 or mitzy.l.schaney@usace.army.mil if you require additional...of the phased compliance approach. Also include any concerns you would like addressed in our evaluation. Please contact Mitzy L. Schaney at (615) 736

  4. Response to Comments on: "Nonlinear phenomena, bifurcations, and routes to chaos in an asymmetrically supported rotor-stator contact system" by Philip Varney, Itzhak Green [J. Sound Vib. 336 (2015) 207-226

    NASA Astrophysics Data System (ADS)

    Varney, Philip; Green, Itzhak

    2017-11-01

    The authors would like to thank the discussers for their interest in the paper. The discussers raise several objections to the original work; namely, that the state-space equations of motion were derived incorrectly, thus rendering the original results incorrect by association. In actuality, the error in the original state-space equations (Eq. (16) in the original work) is typographic only. This, in conjunction with a typographic error in Table A1, prevented the discussers from replicating a subset of the original results (though the discussers were able to replicate many of the results presented in the original work, despite the presumed error in the equations). These typographic errors are rectified here. In addition, results are presented here corresponding to the solution that would have been obtained had the state-space equations been incorrect in the manner presumed by the discussers. Finally, the discussers state that the results presented in the original work do not adhere to physical principles because the steady-state solution in one case indicates contact even though the linear response to imbalance is less than the radial clearance. This seeming discrepancy is also addressed here.

  5. 5 CFR 2600.102 - Contact information.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 5 Administrative Personnel 3 2013-01-01 2013-01-01 false Contact information. 2600.102 Section... AND FUNCTIONS OF THE OFFICE OF GOVERNMENT ETHICS § 2600.102 Contact information. (a) Address. The.... OGE does not have any regional offices. (b) Web site. Information about OGE and its role in the...

  6. 78 FR 38303 - Privacy Act of 1974; System of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-26

    ....regulations.gov as they are received without change, including any personal identifiers or contact information. FOR FURTHER INFORMATION CONTACT: Mr. Leroy Jones, Department of the Army, Privacy Office, U.S. Army... published in the Federal Register and are available from the address in FOR FURTHER INFORMATION CONTACT or...

  7. 77 FR 61582 - Privacy Act of 1974; System of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-10

    ... change, including any personal identifiers or contact information FOR FURTHER INFORMATION CONTACT: Mr..., have been published in FOR FURTHER INFORMATION CONTACT. The proposed system report, as required by 5 U...: Delete entry and replace with ``Social Security Number (SSN), name, home address, phone numbers or other...

  8. SAM Technical Contacts

    EPA Pesticide Factsheets

    These technical contacts are available to help with questions regarding method deviations, modifications, sample problems or interferences, quality control requirements, the use of alternative methods, or the need to address analytes or sample types.

  9. 16 CFR 436.3 - Cover page.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... business address, telephone number, and, if applicable, email address and primary home page address. (c) A... Commission. You can contact the FTC at 1-877-FTC-HELP or by writing to the FTC at 600 Pennsylvania Avenue, NW...

  10. 78 FR 75329 - Information Collection; Disaster Assistance (General)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-11

    ... comments. Mail: Dan McGlynn, Acting Director, Production, Emergencies and Compliance Division, Farm Service... contacting Dan McGlynn at the above addresses. FOR FURTHER INFORMATION CONTACT: Steve Peterson, Branch Chief...

  11. Resistivity of Rotated Graphite-Graphene Contacts.

    PubMed

    Chari, Tarun; Ribeiro-Palau, Rebeca; Dean, Cory R; Shepard, Kenneth

    2016-07-13

    Robust electrical contact of bulk conductors to two-dimensional (2D) material, such as graphene, is critical to the use of these 2D materials in practical electronic devices. Typical metallic contacts to graphene, whether edge or areal, yield a resistivity of no better than 100 Ω μm but are typically >10 kΩ μm. In this Letter, we employ single-crystal graphite for the bulk contact to graphene instead of conventional metals. The graphite contacts exhibit a transfer length up to four-times longer than in conventional metallic contacts. Furthermore, we are able to drive the contact resistivity to as little as 6.6 Ω μm(2) by tuning the relative orientation of the graphite and graphene crystals. We find that the contact resistivity exhibits a 60° periodicity corresponding to crystal symmetry with additional sharp decreases around 22° and 39°, which are among the commensurate angles of twisted bilayer graphene.

  12. Interaction between descending input and thoracic reflexes for joint coordination in cockroach: I. descending influence on thoracic sensory reflexes.

    PubMed

    Mu, Laiyong; Ritzmann, Roy E

    2008-03-01

    Tethered cockroaches turn from unilateral antennal contact using asymmetrical movements of mesothoracic (T2) legs (Mu and Ritzmann in J Comp Physiol A 191:1037-1054, 2005). During the turn, the leg on the inside of the turn (the inside T2 leg) has distinctly different motor patterns from those in straight walking. One possible neural mechanism for the transformation from walking to inside leg turning could be that the descending commands alter a few critical reflexes that start a cascade of physical changes in leg movement or posture, leading to further alterations. This hypothesis has two implications: first, the descending activities must be able to influence thoracic reflexes. Second, one should be able to initiate the turning motor pattern without descending signals by mimicking a point farther down in the reflex cascade. We addressed the first implication in this paper by experiments on chordotonal organ reflexes. The activity of depressor muscle (Ds) and slow extensor tibia muscle (SETi) was excited and inhibited by stretching and relaxing the femoral chordotonal organ. However, the Ds responses were altered after eliminating the descending activity, while the SETi responses remain similar. The inhibition to Ds activity by stretching the coxal chordotonal organ was also altered after eliminating the descending activity.

  13. Contact Dermatitis in Pediatrics.

    PubMed

    Pelletier, Janice L; Perez, Caroline; Jacob, Sharon E

    2016-08-01

    Contact dermatitis is an umbrella term that describes the skin's reaction to contacted noxious or allergenic substances. The two main categories of contact dermatitis are irritant type and allergic type. This review discusses the signs, symptoms, causes, and complications of contact dermatitis. It addresses the testing, treatment, and prevention of contact dermatitis. Proper management of contact dermatitis includes avoidance measures for susceptible children. Implementation of a nickel directive (regulating the use of nickel in jewelry and other products that come into contact with the skin) could further reduce exposure to the most common allergens in the pediatric population. [Pediatr Ann. 2016;45(8):e287-e292.]. Copyright 2016, SLACK Incorporated.

  14. 78 FR 53581 - Endangered and Threatened Wildlife and Plants; Threatened Status for Oregon Spotted Frog

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-29

    ... INFORMATION CONTACT by October 15, 2013. ADDRESSES: Written Comments: You may submit comments by one of the... (see the Public Comments section below for more information). FOR FURTHER INFORMATION CONTACT: Ken Berg... FOR FURTHER INFORMATION CONTACT). Previous Federal Actions We received a petition dated May 1, 1989...

  15. 31 CFR 351.2 - How do I contact Public Debt?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... SERVICE, DEPARTMENT OF THE TREASURY BUREAU OF THE PUBLIC DEBT OFFERING OF UNITED STATES SAVINGS BONDS, SERIES EE General Information § 351.2 How do I contact Public Debt? You may contact Public Debt by e-mail at [email protected], or by writing to the following address: Bureau of the Public Debt...

  16. Influence of occlusal contact area on cusp defection and stress distribution.

    PubMed

    Costa, Anna Karina Figueiredo; Xavier, Thaty Aparecida; Paes-Junior, Tarcisio José Arruda; Andreatta-Filho, Oswaldo Daniel; Borges, Alexandre Luiz Souto

    2014-11-01

    The purpose of this study was to evaluate the effect of occlusal contact area for loading on the cuspal defection and stress distribution in a first premolar restored with a high elastic modulus restorative material. The Rhinoceros 4.0 software was used for modeling the three-dimensional geometries of dental and periodontal structures and the inlay restoration. Thus, two different models, intact and restored teeth with three occlusal contact areas, 0.1, 0.5 and 0.75 mm(2), on enamel at the occlusal surface of buccal and lingual cusps. Finite element analysis (FEA) was performed with the program ANSYS (Workbench 13.0), which generated a mesh with tetrahedral elements with greater refinement in the regions of interest, and was constrained at the bases of cortical and trabecular bone in all axis and loaded with 100 N normal to each contact area. To analysis of maximum principal stress, the smaller occlusal contact area showed greater compressive stress in region of load application for both the intact and inlay restored tooth. However, tensile stresses at the occlusal isthmus were similar for all three tested occlusal contact areas (60 MPa). To displacement of the cusps was higher for teeth with inlay (0.46-0.48 mm). For intact teeth, the smaller contact area showed greater displacement (0.10 mm). For teeth with inlays, the displacement of the cusps were similar in all types of occlusal area. Cuspal displacement was higher in the restored tooth when compared to the intact tooth, but there were no significant variations even with changes in the occlusal contact area. RELEVANCE CLINICAL: Occlusal contacts have a great influence on the positioning of teeth being able to maintain the position and stability of the mandible. Axial loads would be able to generate more uniform stress at the root presenting a greater concentration of load application in the point and the occlusal surface. Thus, is necessary to analyze the relationship between these occlusal contacts as dental wear and subsequent occlusal interferences.

  17. Reduction of plantar pressures in leprosy patients by using custom made shoes and total contact insoles.

    PubMed

    Tang, Simon Fuk-Tan; Chen, Carl P C; Lin, Shih-Cherng; Wu, Chih-Kuan; Chen, Chih-Kuang; Cheng, Shun-Ping

    2015-02-01

    The purpose of this study was to observe whether our custom made shoes and total contact insoles can effectively increase the plantar contact areas and reduce peak pressures in patients with leprosy. In the rehabilitation laboratory of a tertiary medical center. Six male and two female leprosy patients were recruited in this study. In this study, parameters related to foot pressures were compared between these patients wearing commercial available soft-lining kung-fu shoes and our custom made shoes with total contact insoles. The custom made shoes were made with larger toe box and were able to accommodate both the foot and the insoles. Custom made total contact insoles were made with the subtalar joints under neutral and non-weight-bearing positions. The insole force measurement system of Novel Pedar-X (Novel, Munich, Germany) was used to measure the plantar forces. The parameters of contact area (cm(2)), peak plantar pressures (kPa), contact time (s), and pressure time integral (kPa s) were measured. There were significant contact area increases in the right and left foot heel areas, left medial arch, and second to fifth toes after wearing the custom made shoes and insoles. There were significant decreases in peak plantar pressures in bilateral heels, left lateral midfoot, bilateral second to fourth metatarsal areas, and left fifth metatarsal head after wearing the custom made shoes and insoles (p<0.05). Plantar ulceration is a common serious disability in leprosy patients. As a result, footwear and measures able to reduce plantar pressures may be beneficial in preventing plantar ulcers from occurring in these patients. Our custom made shoes and total contact insoles were proven to be effective in increasing contact areas and decreasing peak pressures in plantar surfaces, and may therefore be a feasible treatment option in preventing leprosy patients from developing plantar ulcers. © 2015 Elsevier B.V. All rights reserved.

  18. 77 FR 40565 - Northwest Forest Plan Provincial Advisory Committees

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-10

    .... Addresses: 215 Melody Lane, Wenatchee, WA, 98801. For Further Information Contact: Robin DeMario, 509-664... Highway 12, Naches, WA. For Further Information Contact: Robin DeMario, 509-664-9292. Deschutes PAC...

  19. 76 FR 81480 - Gulf of Mexico Fishery Management Council; Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-28

    ... CONTACT: Dr. Richard Leard, Deputy Executive Director/Senior Fishery Biologist; Gulf of Mexico Fishery... contact Kathy Pereira at the Council (see ADDRESSES) at least 5 working days prior to the webinar. Dated...

  20. 78 FR 23940 - Use of International Standard ISO-10993, “Biological Evaluation of Medical Devices Part 1...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-23

    ... requests for medical devices that come into direct or indirect contact with the human body in order to... the human body in order to determine the potential toxicity resulting from contact of the component... direct or indirect contact with the human body. This document addresses the following issues: (1) Test...

  1. 75 FR 22671 - Self-Regulatory Organizations; New York Stock Exchange LLC; Notice of Filing and Immediate...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-29

    ... Proposed Rule Change To Amend Its Immediate Release Policy To Remove the Address Contact Information April... Manual (the ``Manual'') to remove the contact information provided in that rule for national news wire... Press International. As a convenience, the Exchange has included in Section 202.06(c) \\5\\ [sic] contact...

  2. Poor reporting of scientific leadership information in clinical trial registers.

    PubMed

    Sekeres, Melanie; Gold, Jennifer L; Chan, An-Wen; Lexchin, Joel; Moher, David; Van Laethem, Marleen L P; Maskalyk, James; Ferris, Lorraine; Taback, Nathan; Rochon, Paula A

    2008-02-20

    In September 2004, the International Committee of Medical Journal Editors (ICMJE) issued a Statement requiring that all clinical trials be registered at inception in a public register in order to be considered for publication. The World Health Organization (WHO) and ICMJE have identified 20 items that should be provided before a trial is considered registered, including contact information. Identifying those scientifically responsible for trial conduct increases accountability. The objective is to examine the proportion of registered clinical trials providing valid scientific leadership information. We reviewed clinical trial entries listing Canadian investigators in the two largest international and public trial registers, the International Standard Randomized Controlled Trial Number (ISRCTN) register, and ClinicalTrials.gov. The main outcome measures were the proportion of clinical trials reporting valid contact information for the trials' Principal Investigator (PI)/Co-ordinating Investigator/Study Chair/Site PI, and trial e-mail contact address, stratified by funding source, recruiting status, and register. A total of 1388 entries (142 from ISRCTN and 1246 from ClinicalTrials.gov) comprised our sample. We found non-compliance with mandatory registration requirements regarding scientific leadership and trial contact information. Non-industry and partial industry funded trials were significantly more likely to identify the individual responsible for scientific leadership (OR = 259, 95% CI: 95-701) and to provide a contact e-mail address (OR = 9.6, 95% CI: 6.6-14) than were solely industry funded trials. Despite the requirements set by WHO and ICMJE, data on scientific leadership and contact e-mail addresses are frequently omitted from clinical trials registered in the two leading public clinical trial registers. To promote accountability and transparency in clinical trials research, public clinical trials registers should ensure adequate monitoring of trial registration to ensure completion of mandatory contact information fields identifying scientific leadership.

  3. 78 FR 41928 - Notice of Meeting of the EPA's Children's Health Protection Advisory Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-12

    ..., 2013. ADDRESSES: 2777 South Crystal Drive, Arlington, VA 22202. FOR FURTHER INFORMATION CONTACT: Martha... information on access or services for individuals with disabilities, please contact Martha Berger at 202- 564...

  4. 75 FR 79330 - Negotiated Rulemaking Committee on Designation of Medically Underserved Populations and Health...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-20

    ... more information, please contact Nicole Patterson, Office of Shortage Designation, Bureau of Health... written comments to the Committee should be sent to Nicole Patterson at the contact address above at least...

  5. Design and Stress Analysis of Low-Noise Adjusted Bearing Contact Spiral Bevel Gears

    NASA Technical Reports Server (NTRS)

    Litvin, Faydor L.; Fuentes, Alfonso; Mullins, Baxter R.; Woods, Ron

    2002-01-01

    An integrated computerized approach for design and stress analysis of low-noise spiral bevel gear drives with adjusted bearing contact has been developed. The computation procedure is an iterative process, requiring four separate steps that provide: (a) a parabolic function of transmission errors that is able to reduce the effect of errors of alignment, and (b) reduction of the shift of bearing contact caused by misalignment. Application of finite element analysis permits the contact and bending stresses to be determined and investigate the formation of the bearing contact. The design of finite element models and boundary conditions is automated and does not require an intermediate CAD computer program. A commercially available finite element analysis computer program with contact capability was used to conduct the stress analysis. The theory developed is illustrated with numerical examples.

  6. Merging economics and epidemiology to improve the prediction and management of infectious disease.

    PubMed

    Perrings, Charles; Castillo-Chavez, Carlos; Chowell, Gerardo; Daszak, Peter; Fenichel, Eli P; Finnoff, David; Horan, Richard D; Kilpatrick, A Marm; Kinzig, Ann P; Kuminoff, Nicolai V; Levin, Simon; Morin, Benjamin; Smith, Katherine F; Springborn, Michael

    2014-12-01

    Mathematical epidemiology, one of the oldest and richest areas in mathematical biology, has significantly enhanced our understanding of how pathogens emerge, evolve, and spread. Classical epidemiological models, the standard for predicting and managing the spread of infectious disease, assume that contacts between susceptible and infectious individuals depend on their relative frequency in the population. The behavioral factors that underpin contact rates are not generally addressed. There is, however, an emerging a class of models that addresses the feedbacks between infectious disease dynamics and the behavioral decisions driving host contact. Referred to as "economic epidemiology" or "epidemiological economics," the approach explores the determinants of decisions about the number and type of contacts made by individuals, using insights and methods from economics. We show how the approach has the potential both to improve predictions of the course of infectious disease, and to support development of novel approaches to infectious disease management.

  7. AGARD Guide to Aerospace and Defence Technical Report Series in NATO countries. Revision

    DTIC Science & Technology

    1991-03-01

    TNOI Medisch Biologisch laboratorium TNO [MBL] Contact Person’ Address: P0 Box 45 2280 AA Rijswijk (ZH) Country NETHERLANDS Telephone : 31-15-138777... Laboratorium [WLJ Contact Person : Address: PO Box 177 2600 MH Delft Country: NETHERLANDS Telephone : 31-15-569353 Telex OR TWX; 38176 Type of Organization...STEVINJ 1 2 3 LV-R-[NN.YY] Report of Laboratory of Fluid Mechanics-TUD 1 2 3 Laboratorium voor Vloeistofmnechanica-TUD [LVI Notes: 1 Formal Report 2

  8. 45 CFR 149.40 - Application.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ...'s name and address. (3) Contact name, telephone number and email address. (4) Plan sponsor agreement signed by an authorized representative, which includes— (i) An assurance that the sponsor has a written...

  9. 76 FR 77327 - Disciplinary Appeals Board Panel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-12

    .... FOR FURTHER INFORMATION CONTACT: Larry Ables, Employee Relations and Performance Management Service, Office of Human Resources Management, Department of Veterans Affairs, 810 Vermont Avenue NW., Mailstop...

  10. 21 CFR 1.232 - What information is required in the registration?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... address, and phone number of the facility; (b) The name, address, and phone number of the parent company... names, addresses, and phone numbers of the owner, operator, and agent in charge. (d) For a foreign facility, the name, address, phone number, and, if no emergency contact is designated under § 1.233(e), the...

  11. 21 CFR 1.232 - What information is required in the registration?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... address, and phone number of the facility; (b) The name, address, and phone number of the parent company... names, addresses, and phone numbers of the owner, operator, and agent in charge. (d) For a foreign facility, the name, address, phone number, and, if no emergency contact is designated under § 1.233(e), the...

  12. 21 CFR 1.232 - What information is required in the registration?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... address, and phone number of the facility; (b) The name, address, and phone number of the parent company... names, addresses, and phone numbers of the owner, operator, and agent in charge. (d) For a foreign facility, the name, address, phone number, and, if no emergency contact is designated under § 1.233(e), the...

  13. 21 CFR 1.232 - What information is required in the registration?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... address, and phone number of the facility; (b) The name, address, and phone number of the parent company... names, addresses, and phone numbers of the owner, operator, and agent in charge. (d) For a foreign facility, the name, address, phone number, and, if no emergency contact is designated under § 1.233(e), the...

  14. 21 CFR 1.232 - What information is required in the registration?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... address, and phone number of the facility; (b) The name, address, and phone number of the parent company... names, addresses, and phone numbers of the owner, operator, and agent in charge. (d) For a foreign facility, the name, address, phone number, and, if no emergency contact is designated under § 1.233(e), the...

  15. 77 FR 71873 - Disciplinary Appeals Board Panel

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-04

    ... CONTACT: Larry Ables, Employee Relations and Performance Management Service (051), Office of Human Resources Management, Department of Veterans Affairs, 810 Vermont Avenue NW., Washington, DC 20420. Mr...

  16. 77 FR 66832 - Notice of Receipt of Pesticide Products; Registration Applications To Register New Uses

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-07

    ..., tallow wood, tea oil plant, and vernonia). Contact: Bethany Benbow, (703) 347-8072, email address: benbow... seed, rose hip, sesame, Stokes aster, sweet rocket, tallow wood, tea oil plant, and vernonia). Contact...

  17. 77 FR 28281 - Withdrawal of Revocation of TSCA Section 4 Testing Requirements for One High Production Volume...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-14

    ... information contact: Catherine Roman, Chemical Control Division (7405M), Office of Pollution Prevention and... number: (202) 564-8157; email address: roman[email protected] . For general information contact: The...

  18. 75 FR 67303 - Negotiated Rulemaking Committee on Designation of Medically Underserved Populations and Health...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-02

    ..., please contact Nicole Patterson, Office of Shortage Designation, Bureau of Health Professions, Health... should be sent to Nicole Patterson at the contact address above at least 10 days prior to the meeting...

  19. The (in)stability of 21st century orthopedic patient contact information and its implications on clinical research: a cross-sectional study

    PubMed Central

    London, Daniel A; Stepan, Jeffrey G; Goldfarb, Charles A; Boyer, Martin I; Calfee, Ryan P

    2016-01-01

    Background In clinical research, minimizing patients lost to follow-up is essential for data validity. Researchers can employ better methodology to prevent patient loss. We examined how orthopedic surgery patients’ contact information changes over time to optimize data collection for long-term outcomes research. Methods Patients presenting to orthopedic outpatient clinics completed questionnaires regarding methods of contact: home phone, cell phone, mailing address, and e-mail address. They reported currently available methods of contact, if they changed in the past five and ten years, and when they changed. Differences in the rates of change amongst methods were assessed via Fisher exact tests. Whether participants changed any of their contact information in the past five and ten years was determined via multivariate modeling, controlling for demographic variables. Results Among 152 patients, 51% changed at least one form of contact information within 5 years, and 66% changed at least one form within 10 years. The rate of change for each contact method was similar over five (15-28%) and ten years (26-41%). One patient changed all 4 methods of contact within the past five years, and seven within the past ten years. Females and younger patients were more likely to change some type of contact information. Conclusions The type of contact information least likely to change over five to ten years is influenced by demographic factors such as sex and age, with females and younger participants more likely to change some aspect of their contact information. Collecting all contact methods appears necessary to minimize patients lost to follow-up, especially as technological norms evolve. PMID:28359191

  20. The (in)stability of 21st century orthopedic patient contact information and its implications on clinical research: A cross-sectional study.

    PubMed

    London, Daniel A; Stepan, Jeffrey G; Goldfarb, Charles A; Boyer, Martin I; Calfee, Ryan P

    2017-04-01

    In clinical research, minimizing patients lost to follow-up is essential for data validity. Researchers can employ better methodology to prevent patient loss. We examined how orthopedic surgery patients' contact information changes over time to optimize data collection for long-term outcomes research. Patients presenting to orthopedic outpatient clinics completed questionnaires regarding methods of contact: home phone, cell phone, mailing address, and e-mail address. They reported currently available methods of contact, if they changed in the past 5 and 10 years, and when they changed. Differences in the rates of change among methods were assessed via Fisher's exact tests. Whether participants changed any of their contact information in the past 5 and 10 years was determined via multivariate modeling, controlling for demographic variables. Among 152 patients, 51% changed at least one form of contact information within 5 years, and 66% changed at least one form within 10 years. The rate of change for each contact method was similar over 5 (15%-28%) and 10 years (26%-41%). One patient changed all four methods of contact within the past 5 years and seven within the past 10 years. Females and younger patients were more likely to change some type of contact information. The type of contact information least likely to change over 5-10 years is influenced by demographic factors such as sex and age, with females and younger participants more likely to change some aspect of their contact information. Collecting all contact methods appears necessary to minimize patients lost to follow-up, especially as technological norms evolve.

  1. 75 FR 8069 - Notice of Public Information Collection Being Submitted for Review and Approval to the Office of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-23

    ... should advise the contact listed below as soon as possible. ADDRESSES: Direct all PRA comments to.... FOR FURTHER INFORMATION CONTACT: Judith B. Herman, OMD, 202-418-0214. For additional information about the information collection(s) send an e-mail to [email protected] or contact Judith B. Herman, 202-418-0214...

  2. Importance and Definition of Materials in Tribology. Status of Understanding

    NASA Technical Reports Server (NTRS)

    Buckley, D. H.

    1984-01-01

    In general, tribological systems consist of three basic components: the material surfaces in contact, the lubricant, and the environment. The materials in contact and the influence of both bulk and surface properties, indicating the importance of material characterization, on tribological behavior are addressed. Since metals and metallic alloys are the most widely used class of materials in practical devices, attention is focused principally on them. With respect to surface behavior, the effect of contaminants both from within the material and from the environment on adhesive behavior is addressed. The various surface events that alter adhesion, friction, and wear are discussed. These include surface reconstruction, segregation, chemisorption, and compound formation. Examples of these events are presented. Minor nuances in the structure of the outermost layers of solids have a pronounced effect on tribological properties. The importance of characterizing the materials of solids in contact in order to achieve a fundamental understanding of adhesion, friction, and wear and accordingly of methods for their control are addressed.

  3. 75 FR 19953 - Proposed Agency Information Collection

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-16

    ... anticipate difficulty in submitting comments within that period, contact the person listed in ADDRESSES as soon as possible. ADDRESSES: Written comments may be sent to Christine Askew, U.S. Department of Energy...

  4. The effect of PeakForce tapping mode AFM imaging on the apparent shape of surface nanobubbles.

    PubMed

    Walczyk, Wiktoria; Schön, Peter M; Schönherr, Holger

    2013-05-08

    Until now, TM AFM (tapping mode or intermittent contact mode atomic force microscopy) has been the most often applied direct imaging technique to analyze surface nanobubbles at the solid-aqueous interface. While the presence and number density of nanobubbles can be unequivocally detected and estimated, it remains unclear how much the a priori invasive nature of AFM affects the apparent shapes and dimensions of the nanobubbles. To be able to successfully address the unsolved questions in this field, the accurate knowledge of the nanobubbles' dimensions, radii of curvature etc is necessary. In this contribution we present a comparative study of surface nanobubbles on HOPG (highly oriented pyrolytic graphite) in water acquired with (i) TM AFM and (ii) the recently introduced PFT (PeakForce tapping) mode, in which the force exerted on the nanobubbles rather than the amplitude of the resonating cantilever is used as the AFM feedback parameter during imaging. In particular, we analyzed how the apparent size and shape of nanobubbles depend on the maximum applied force in PFT AFM. Even for forces as small as 73 pN, the nanobubbles appeared smaller than their true size, which was estimated from an extrapolation of the bubble height to zero applied force. In addition, the size underestimation was found to be more pronounced for larger bubbles. The extrapolated true nanoscopic contact angles for nanobubbles on HOPG, measured in PFT AFM, ranged from 145° to 175° and were only slightly underestimated by scanning with non-zero forces. This result was comparable to the nanoscopic contact angles of 160°-175° measured using TM AFM in the same set of experiments. Both values disagree, in accordance with the literature, with the macroscopic contact angle of water on HOPG, measured here to be 63° ± 2°.

  5. Design and Stress Analysis of Low-Noise Adjusted Bearing Contact Spiral Bevel Gears

    NASA Technical Reports Server (NTRS)

    Fuentes, A.; Litvin, F. L.; Mullins, B. R.; Woods, R.; Handschuh, R. F.; Lewicki, David G.

    2002-01-01

    An integrated computerized approach for design and stress analysis of low-noise spiral bevel gear drives with adjusted bearing contact is proposed. The procedure of computations is an iterative process that requires four separate procedures and provide: (a) a parabolic function of transmission errors that is able to reduce the effect of errors of alignment on noise and vibration, and (b) reduction of the shift of bearing contact caused by misalignment. Application of finite element analysis enables us to determine the contact and bending stresses and investigate the formation of the bearing contact. The design of finite element models and boundary conditions is automated and does not require intermediate CAD computer programs for application of general purpose computer program for finite element analysis.

  6. 77 FR 11593 - Proposed Collection, Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-27

    ... in the Addresses section of this notice on or before April 27, 2012. ADDRESSES: Send comments to Nora... (this is not a toll free number). FOR FURTHER INFORMATION CONTACT: Nora Kincaid, BLS Clearance Officer...

  7. Origins of Shear Jamming for Frictional Grains

    NASA Astrophysics Data System (ADS)

    Wang, Dong; Zheng, Hu; Ren, Jie; Dijksman, Joshua; Bares, Jonathan; Behringer, Robert

    2016-11-01

    Granular systems have been shown to be able to behave like solids, under shear, even when their densities are below the critical packing fraction for frictionless isotropic jamming. To understand such a phenomena, called shear jamming, the question we address here is: how does shear bring a system from a unjammed state to a jammed state, where the coordination number, Z, is no less than 3, the isotropic jamming point for frictional grains? Since Z can be used to distinguish jammed states from unjammed ones, it is vital to understand how shear increases Z. We here propose a set of three particles in contact, denoted as a trimer, as the basic unit to characterize the deformation of the system. Trimers, stabilized by inter-grain friction, fail under a certain amount of shear and bend to make extra contacts to regain stability. By defining a projection operator of the opening angle of the trimer to the compression direction in the shear, O, we see a systematically linear decrease of this quantity with respect to shear strain, demonstrating the bending of trimers as expected. In addition, the average change of O from one shear step to the next shows a good collapse when plotted against Z, indicating a universal behavior in the process of shear jamming. We acknowledge support from NSF DMR1206351, NASA NNX15AD38G, the William M. Keck Foundation and a RT-MRSEC Fellowship.

  8. 76 FR 18548 - Clean Water Act Section 303(d): Final Agency Action on Three Total Maximum Daily Loads (TMDLs) in...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-04

    ... Smith at the address below. Please contact Ms. Smith to schedule an inspection. FOR FURTHER INFORMATION CONTACT: Diane Smith, Environmental Protection Specialist, Water Quality Protection Division, U.S. EPA...

  9. 77 FR 1471 - Board of Regents of the Uniformed Services University of the Health Sciences; Quarterly Meeting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-10

    ... FURTHER INFORMATION CONTACT: Janet S. Taylor, Designated Federal Officer, 4301 Jones Bridge Road, Bethesda... meeting should contact Janet S. Taylor at the address and phone number noted in FOR FURTHER INFORMATION...

  10. Report Outlines Promising Opportunities for Addressing Climate Change

    Science.gov Websites

    Report Outlines Promising Opportunities for Addressing Climate Change For more information contact , have issued a major report that finds the United States can make impressive strides toward addressing climate change through smart policies and technologies. The report, "Scenarios for a Clean Energy

  11. Contact sensing from force measurements

    NASA Technical Reports Server (NTRS)

    Bicchi, Antonio; Salisbury, J. K.; Brock, David L.

    1993-01-01

    This article addresses contact sensing (i.e., the problem of resolving the location of a contact, the force at the interface, and the moment about the contact normals). Called 'intrinsic' contact sensing for the use of internal force and torque measurements, this method allows for practical devices that provide simple, relevant contact information in practical robotic applications. Such sensors have been used in conjunction with robot hands to identify objects, determine surface friction, detect slip, augment grasp stability, measure object mass, probe surfaces, and control collision and for a variety of other useful tasks. This article describes the theoretical basis for their operation and provides a framework for future device design.

  12. Electron transport in extended carbon-nanotube/metal contacts: Ab initio based Green function method

    NASA Astrophysics Data System (ADS)

    Fediai, Artem; Ryndyk, Dmitry A.; Cuniberti, Gianaurelio

    2015-04-01

    We have developed a new method that is able to predict the electrical properties of the source and drain contacts in realistic carbon nanotube field effect transistors (CNTFETs). It is based on large-scale ab initio calculations combined with a Green function approach. For the first time, both internal and external parts of a realistic CNT-metal contact are taken into account at the ab initio level. We have developed the procedure allowing direct calculation of the self-energy for an extended contact. Within the method, it is possible to calculate the transmission coefficient through a contact of both finite and infinite length; the local density of states can be determined in both free and embedded CNT segments. We found perfect agreement with the experimental data for Pd and Al contacts. We have explained why CNTFETs with Pd electrodes are p -type FETs with ohmic contacts, which can carry current close to the ballistic limit (provided contact length is large enough), whereas in CNT-Al contacts transmission is suppressed to a significant extent, especially for holes.

  13. Synaptotagmin-mediated bending of the target membrane is a critical step in Ca2+-regulated fusion

    PubMed Central

    Hui, Enfu; Johnson, Colin P.; Yao, Jun; Dunning, F. Mark; Chapman, Edwin R.

    2009-01-01

    Summary Decades ago it was proposed that exocytosis involves invagination of the target membrane, resulting in a highly localized site of contact between the bilayers destined to fuse. The vesicle protein synaptotagmin-I (syt) bends membranes in response to Ca2+, but whether this drives localized invagination of the target membrane to accelerate fusion has not been determined; previous studies relied on reconstituted vesicles that were already highly curved and used mutations in syt that were not selective for membrane-bending activity. Here, we directly address this question by utilizing vesicles with different degrees of curvature. A tubulation-defective syt mutant was able to promote fusion between highly curved SNARE-bearing liposomes, but exhibited a marked loss of activity when the membranes were relatively flat. Moreover, bending of flat membranes by adding an N-BAR domain rescued the function of the tubulation-deficient syt mutant. Hence, syt-mediated membrane bending is a critical step in membrane fusion. PMID:19703397

  14. A high resolution PVDF (peizoelectric) film respiration sensor

    NASA Astrophysics Data System (ADS)

    Nakano, Katsuya; Fujita, Kento; Misaki, Shinya; Fujii, Hiroyuki; Johnston, Robert; Misaki, Yukinori

    2017-07-01

    Sensors used today for contact measurement of a subject's breathing work by measuring the inductance change in some film, piezoelectric or pyro-electric, used in the sensor. However, their use can increase stress and burden for patients because of the close proximity to the body that the sensors must be to operate. They must be applied directly to the patient's body by tape or adhesive paste. To address this problem and reduce subject stress and burden, it was decided to research development of a high resolution breathing sensor that could still function even while placed over the patient's clothes. This was achieved by developing a new PVDF piezoelectric film based sensor with an innovative configuration. Through the use of some simple amplification circuitry and processing the output signal, the high sensitivity breathing sensor developed was determined to be able to accurately measure a person's breathing. Also, due to the high sensitivity of the sensor, heart rate was also detectable revealing the possibility for simultaneous measurement of both breathing and heart rate.

  15. 31 CFR 351.2 - How do I contact Fiscal Service?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Service by e-mail at [email protected]gov, or by writing to the following address: Bureau of the Fiscal Service, Parkersburg, West Virginia 26106-1328. Our website address is www.savingsbonds.gov. ...

  16. Hip replacement - discharge

    MedlinePlus

    ... such as downhill skiing or contact sports like football and soccer. But you should be able to ... herein should not be used during any medical emergency or for the diagnosis or treatment of any ...

  17. Knee joint replacement - discharge

    MedlinePlus

    ... such as downhill skiing or contact sports like football and soccer. But, you should be able to ... herein should not be used during any medical emergency or for the diagnosis or treatment of any ...

  18. Contact interaction in an unitary ultracold Fermi gas

    DOE PAGES

    Pessoa, Renato; Gandolfi, Stefano; Vitiello, S. A.; ...

    2015-12-16

    An ultracold Fermi atomic gas at unitarity presents universal properties that in the dilute limit can be well described by a contact interaction. By employing a guiding function with correct boundary conditions and making simple modifications to the sampling procedure we are able to calculate the properties of a true contact interaction with the diffusion Monte Carlo method. The results are obtained with small variances. Our calculations for the Bertsch and contact parameters are in excellent agreement with published experiments. The possibility of using a more faithful description of ultracold atomic gases can help uncover additional features of ultracold atomicmore » gases. In addition, this work paves the way to perform quantum Monte Carlo calculations for other systems interacting with contact interactions, where the description using potentials with finite effective range might not be accurate.« less

  19. 17 CFR 31.18 - Margin calls.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... a margin deficiency without effecting personal contact with the leverage customer. If a leverage transaction merchant is unable to effect personal contact with a leverage customer, a telegram sent to the leverage customer at the address furnished by the customer to the leverage transaction merchant shall be...

  20. 78 FR 34669 - Incidental Take Permit and Environmental Assessment for Forest Management Activities, Southern...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-10

    ... 72032. FOR FURTHER INFORMATION CONTACT: Mr. David Dell, Regional HCP Coordinator, (see ADDRESSES... internet to david_dell@fws.gov . Please include your name and return address in your internet message. If...

  1. 77 FR 14571 - Waste Regulation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-12

    .... FOR FURTHER INFORMATION CONTACT: Polly A. Penhale, Environmental Officer, at the above address or (703... identified as: Lockheed Martin Corporation, Information Systems & Global Solutions (I&GS) Engineering... holder's address to: Lockheed Corporation, Information Systems & Global Solutions (I&GS) Engineering...

  2. 76 FR 7559 - Access in Litigation to Confidential Business Information; Transfer of Information Claimed as...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-10

    ..., 2011. ADDRESSES: For further information contact Craig Kaufman, Attorney- Advisor, Office of Site...), Washington, DC 20460; telephone number: (202) 564-4284; e-mail address: kaufman[email protected] . SUPPLEMENTARY...

  3. Eldercare at Home: Vision Problems

    MedlinePlus

    ... Contact Aging & Health A to Z Find a Geriatrics Healthcare Professional Medications & Older Adults Making Your Wishes ... including over-the-counter medicines, herbal, and alternative therapies. They may be able to suggest other safer ...

  4. Family and Youth Services Bureau

    MedlinePlus

    ... Quick Fact who age out of foster care report not being able to pay their rent in ... Featured Resources 2016 National Runaway Safeline Crisis Contacts Report November 2, 2017 PREP Research and Evaluation Resources ...

  5. Melanin dependent survival of Apergillus fumigatus conidia in lung epithelial cells.

    PubMed

    Amin, Shayista; Thywissen, Andreas; Heinekamp, Thorsten; Saluz, Hans Peter; Brakhage, Axel A

    2014-07-01

    Aspergillus fumigatus is the most important air-borne pathogenic fungus of humans. Upon inhalation of conidia, the fungus makes close contact with lung epithelial cells, which only possess low phagocytic activity. These cells are in particular interesting to address the question whether there is some form of persistence of conidia of A. fumigatus in the human host. Therefore, by also using uracil-auxotrophic mutant strains, we were able to investigate the interaction of A549 lung epithelial cells and A. fumigatus conidia in detail for long periods. Interestingly, unlike professional phagocytes, our study showed that the presence of conidial dihydroxynaphthalene (DHN) melanin enhanced the uptake of A. fumigatus conidia by epithelial cells when compared with non-pigmented pksP mutant conidia. Furthermore, conidia of A. fumigatus were able to survive within epithelial cells. This was due to the presence of DHN melanin in the cell wall of conidia, because melanised wild-type conidia showed a higher survival rate inside epithelial cells and led to inhibition of acidification of phagolysosomes. Both effects were not observed for white (non-melanised) conidia of the pksP mutant strain. Moreover, in contrast to pksP mutant conidia, melanised wild-type conidia were able to inhibit the extrinsic apoptotic pathway in A549 lung epithelial cells even for longer periods. The anti-apoptotic effect was not restricted to conidia, because both conidia-derived melanin ghosts (cell-free DHN melanin) and a different type of melanin, dihydroxyphenylalanine (DOPA) melanin, acted anti-apoptotically. Taken together, these data indicate the possibility of melanin-dependent persistence of conidia in lung epithelial cells. Copyright © 2014 Elsevier GmbH. All rights reserved.

  6. POINTS-OF-CONTACT (AIR POLLUTION TECHNOLOGY BRANCH, AIR POLLUTION PREVENTION AND CONTROL DIVISION, NRMRL)

    EPA Science Inventory

    The Air Pollution Technology Branch's (APTB) Point-of-Contact page lists APTB research areas along with the name, telephone number, and e-mail address for each responsible person. APTB's research areas include NOx Control, Hazardous Waste Incineration, Municipal Waste Combustion,...

  7. Anatomy of point-contact Andreev reflection spectroscopy from the experimental point of view

    NASA Astrophysics Data System (ADS)

    Naidyuk, Yu. G.; Gloos, K.

    2018-04-01

    We review applications of point-contact Andreev-reflection spectroscopy to study elemental superconductors, where theoretical conditions for the smallness of the point-contact size with respect to the characteristic lengths in the superconductor can be satisfied. We discuss existing theoretical models and identify new issues that have to be solved, especially when applying this method to investigate more complex superconductors. We will also demonstrate that some aspects of point-contact Andreev-reflection spectroscopy still need to be addressed even when investigating ordinary metals.

  8. 78 FR 59661 - Revision of a Currently Approved Information Collection for the State Energy Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-27

    ... October 28, 2013. If you anticipate difficulty in submitting comments within that period, contact the person listed in ADDRESSES as soon as possible. ADDRESSES: Written comments may be sent to Christine...

  9. 78 FR 45910 - Proposed Information Collection; Comment Request; Current Population Survey (CPS) Email Address...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-30

    ... associated with the multiple personal visits. The email could also be as simple as a ``Thank You'' with... collecting email addresses and collecting interest in being contacted by email or answering the survey...

  10. 77 FR 32021 - Significant New Use Rule on a Certain Chemical Substance; Withdrawal of Significant New Use Rule

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-31

    ... address: [email protected] . For general information contact: The TSCA-Hotline, ABVI-Goodwill, 422 South Clinton Ave., Rochester, NY 14620; telephone number: (202) 554-1404; email address: TSCA-Hotline...

  11. 31 CFR 363.5 - How do I contact Public Debt?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... TreasuryDirect ® to communicate information to us over a secure Internet connection. (b) Emails may be sent... should be addressed to the address provided on our web site at http://www.treasurydirect.gov/write.htm...

  12. Towards an optimal contact metal for CNTFETs.

    PubMed

    Fediai, Artem; Ryndyk, Dmitry A; Seifert, Gotthard; Mothes, Sven; Claus, Martin; Schröter, Michael; Cuniberti, Gianaurelio

    2016-05-21

    Downscaling of the contact length Lc of a side-contacted carbon nanotube field-effect transistor (CNTFET) is challenging because of the rapidly increasing contact resistance as Lc falls below 20-50 nm. If in agreement with existing experimental results, theoretical work might answer the question, which metals yield the lowest CNT-metal contact resistance and what physical mechanisms govern the geometry dependence of the contact resistance. However, at the scale of 10 nm, parameter-free models of electron transport become computationally prohibitively expensive. In our work we used a dedicated combination of the Green function formalism and density functional theory to perform an overall ab initio simulation of extended CNT-metal contacts of an arbitrary length (including infinite), a previously not achievable level of simulations. We provide a systematic and comprehensive discussion of metal-CNT contact properties as a function of the metal type and the contact length. We have found and been able to explain very uncommon relations between chemical, physical and electrical properties observed in CNT-metal contacts. The calculated electrical characteristics are in reasonable quantitative agreement and exhibit similar trends as the latest experimental data in terms of: (i) contact resistance for Lc = ∞, (ii) scaling of contact resistance Rc(Lc); (iii) metal-defined polarity of a CNTFET. Our results can guide technology development and contact material selection for downscaling the length of side-contacts below 10 nm.

  13. Lessons Learnt From Hurricane Katrina.

    NASA Astrophysics Data System (ADS)

    Akundi, Murty

    2008-03-01

    Hurricane Katrina devastated New Orleans and its suburbs on Monday August 29^th, 2005. The previous Friday morning, August 26, the National Hurricane Center indicated that Katrina was a Category One Hurricane, which was expected to hit Florida. By Friday afternoon, it had changed its course, and neither the city nor Xavier University was prepared for this unexpected turn in the hurricane's path. The university had 6 to 7 ft of water in every building and Xavier was closed for four months. Students and university personnel that were unable to evacuate were trapped on campus and transportation out of the city became a logistical nightmare. Email and all electronic systems were unavailable for at least a month, and all cell phones with a 504 area code stopped working. For the Department, the most immediate problem was locating faculty and students. Xavier created a list of faculty and their new email addresses and began coordinating with faculty. Xavier created a web page with advice for students, and the chair of the department created a separate blog with contact information for students. The early lack of a clear method of communication made worse the confusion and dismay among the faculty on such issues as when the university would reopen, whether the faculty would be retained, whether they should seek temporary (or permanent) employment elsewhere, etc. With the vision and determination of President Dr. Francis, Xavier was able to reopen the university in January and ran a full academic year from January through August. Since Katrina, the university has asked every department and unit to prepare emergency preparedness plans. Each department has been asked to collect e-mail addresses (non-Xavier), cell phone numbers and out of town contact information. The University also established an emergency website to communicate. All faculty have been asked to prepare to teach classes electronically via Black board or the web. Questions remain about the longer term issues of the size and stability of the faculty.

  14. Modeling contact angle hysteresis of a liquid droplet sitting on a cosine wave-like pattern surface.

    PubMed

    Promraksa, Arwut; Chen, Li-Jen

    2012-10-15

    A liquid droplet sitting on a hydrophobic surface with a cosine wave-like square-array pattern in the Wenzel state is simulated by using the Surface Evolver to determine the contact angle. For a fixed drop volume, multiple metastable states are obtained at two different surface roughnesses. Unusual and non-circular shape of the three-phase contact line of a liquid droplet sitting on the model surface is observed due to corrugation and distortion of the contact line by structure of the roughness. The contact angle varies along the contact line for each metastable state. The maximum and minimum contact angles among the multiple metastable states at a fixed viewing angle correspond to the advancing and the receding contact angles, respectively. It is interesting to observe that the advancing/receding contact angles (and contact angle hysteresis) are a function of viewing angle. In addition, the receding (or advancing) contact angles at different viewing angles are determined at different metastable states. The contact angle of minimum energy among the multiple metastable states is defined as the most stable (equilibrium) contact angle. The Wenzel model is not able to describe the contact angle along the three-phase contact line. The contact angle hysteresis at different drop volumes is determined. The number of the metastable states increases with increasing drop volume. Drop volume effect on the contact angles is also discussed. Crown Copyright © 2012. Published by Elsevier Inc. All rights reserved.

  15. Inferring Epidemic Contact Structure from Phylogenetic Trees

    PubMed Central

    Leventhal, Gabriel E.; Kouyos, Roger; Stadler, Tanja; von Wyl, Viktor; Yerly, Sabine; Böni, Jürg; Cellerai, Cristina; Klimkait, Thomas; Günthard, Huldrych F.; Bonhoeffer, Sebastian

    2012-01-01

    Contact structure is believed to have a large impact on epidemic spreading and consequently using networks to model such contact structure continues to gain interest in epidemiology. However, detailed knowledge of the exact contact structure underlying real epidemics is limited. Here we address the question whether the structure of the contact network leaves a detectable genetic fingerprint in the pathogen population. To this end we compare phylogenies generated by disease outbreaks in simulated populations with different types of contact networks. We find that the shape of these phylogenies strongly depends on contact structure. In particular, measures of tree imbalance allow us to quantify to what extent the contact structure underlying an epidemic deviates from a null model contact network and illustrate this in the case of random mixing. Using a phylogeny from the Swiss HIV epidemic, we show that this epidemic has a significantly more unbalanced tree than would be expected from random mixing. PMID:22412361

  16. 17 CFR 230.134 - Communications not deemed a prospectus.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... in section 2(a)(10) of the Act or “free writing prospectus” as defined in Rule 405 (§ 230.405) shall... number, and e-mail address of the issuer's principal offices and contact for investors, the issuer's... name, address, phone number, and e-mail address of the sender of the communication and the fact that it...

  17. 7 CFR 1494.301 - Information required for program participation.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ...—EEP Contacts: (1) The address of the interested person's office and the name and address of an agent... interested person, if the interested person is a corporation; (4) The name and address of an office(s) of the..., should any such debarment, suspension, or notice of proposed debarment occur in the future, [name of...

  18. Surgery-Related Contact Dermatitis: A Review of Potential Irritants and Allergens.

    PubMed

    Cook, Kevin A; Kelso, John M

    Surgical procedures utilize an increasing number of medical products including antiseptics, anesthetics, gloves, suture materials, tissue adhesives, topical antibiotics, and bandages. Many of these products have irritant potential. Allergic contact dermatitis has also been reported. This review covers preoperative, operative, and postoperative exposures that may result in contact dermatitis. Testing with standard patch panels such as T.R.U.E. Test and the North American Contact Dermatitis Group 65 allergen series does not evaluate for all relevant contactants. A thorough understanding of potential exposures is vital to effectively evaluate a patient with surgery-related contact dermatitis. A systematic approach is needed to ensure that standard patch panels and supplementary patches adequately address each encountered contactant. Copyright © 2017 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  19. Generation and tooth contact analysis of spiral bevel gears with predesigned parabolic functions of transmission errors

    NASA Technical Reports Server (NTRS)

    Litvin, Faydor L.; Lee, Hong-Tao

    1989-01-01

    A new approach for determination of machine-tool settings for spiral bevel gears is proposed. The proposed settings provide a predesigned parabolic function of transmission errors and the desired location and orientation of the bearing contact. The predesigned parabolic function of transmission errors is able to absorb piece-wise linear functions of transmission errors that are caused by the gear misalignment and reduce gear noise. The gears are face-milled by head cutters with conical surfaces or surfaces of revolution. A computer program for simulation of meshing, bearing contact and determination of transmission errors for misaligned gear has been developed.

  20. 15 CFR Appendix A to Subpart C of... - Certification Application Templates

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Contact E-Mail Address This is a request for the above named company or individual (hereinafter referred... Distributor prior to submitting the application. (1) Correspondence and applications/requests for... contact (995.10 (d)). Distributor agrees to immediately notify the Government of any changes to point of...

  1. 75 FR 61099 - Security Zones; Captain of the Port Buffalo Zone; Technical Amendment

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-04

    .... ACTION: Final rule. SUMMARY: The Coast Guard is revising the contact information for Marine Safety... gain permission to transit these areas. DATES: This rule is effective October 4, 2010. ADDRESSES... Friday, except Federal holidays. FOR FURTHER INFORMATION CONTACT: If you have questions on this rule...

  2. 77 FR 11573 - Notice of Inventory Completion: History Colorado, Denver, CO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-27

    ...: History Colorado, Denver, CO AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: History... contact History Colorado. Disposition of the human remains to the Indian tribes stated below may occur if... a cultural affiliation with the human remains should contact History Colorado at the address below...

  3. 7 CFR 1493.20 - Definition of terms.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Secretary of Agriculture. (c) Contacts P/R. A notice issued by FAS/USDA by public press release which contains specific names, addresses, and telephone and facsimile numbers of contacts within FAS/USDA and CCC... appropriate FOB, FAS, CFR or CIF basis. Discounts and allowances include, but are not limited to, the...

  4. 7 CFR 1493.410 - Definition of terms.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Secretary of Agriculture. (c) Contacts P/R. A notice issued by FAS/USDA by public press release which contains specific names, addresses, and telephone and facsimile numbers of contacts within FAS/USDA and CCC... agricultural commodity, above and beyond the commodity's value, stated on the appropriate FOB, FAS, CFR or CIF...

  5. 7 CFR 1493.410 - Definition of terms.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... Secretary of Agriculture. (c) Contacts P/R. A notice issued by FAS/USDA by public press release which contains specific names, addresses, and telephone and facsimile numbers of contacts within FAS/USDA and CCC... agricultural commodity, above and beyond the commodity's value, stated on the appropriate FOB, FAS, CFR or CIF...

  6. 7 CFR 1493.410 - Definition of terms.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Secretary of Agriculture. (c) Contacts P/R. A notice issued by FAS/USDA by public press release which contains specific names, addresses, and telephone and facsimile numbers of contacts within FAS/USDA and CCC... agricultural commodity, above and beyond the commodity's value, stated on the appropriate FOB, FAS, CFR or CIF...

  7. 7 CFR 1493.20 - Definition of terms.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... Secretary of Agriculture. (c) Contacts P/R. A notice issued by FAS/USDA by public press release which contains specific names, addresses, and telephone and facsimile numbers of contacts within FAS/USDA and CCC... appropriate FOB, FAS, CFR or CIF basis. Discounts and allowances include, but are not limited to, the...

  8. 7 CFR 1493.20 - Definition of terms.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Secretary of Agriculture. (c) Contacts P/R. A notice issued by FAS/USDA by public press release which contains specific names, addresses, and telephone and facsimile numbers of contacts within FAS/USDA and CCC... appropriate FOB, FAS, CFR or CIF basis. Discounts and allowances include, but are not limited to, the...

  9. Normalization of load and clearance effects in ball-in-socket-like replacements.

    PubMed

    Ciavarella, M; Strozzi, A; Baldini, A; Giacopini, M

    2007-08-01

    A normalizing loading parameter useful in summarising the mechanical response of plane pin-in-plate-like contacts is extended to axisymmetric ball-in-socket-like contacts. An example addressing a compliant layered artificial hip joint is presented, and the usefulness of the normalizing loading parameter is evidenced.

  10. 76 FR 43332 - Advisory Committee on Interdisciplinary, Community-Based Linkages; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-20

    ... the ACICBL should be sent to Dr. Joan Weiss, Designated Federal Official at the contact information... requesting information regarding the ACICBL should contact Dr. Joan Weiss, Designated Federal Official within...: (1) Send a request to the following address: Dr. Joan Weiss, Designated Federal Official, Bureau of...

  11. 77 FR 19021 - Advisory Committee on Interdisciplinary, Community-Based Linkages; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-29

    ... comments to the ACICBL should be sent to Dr. Joan Weiss, Designated Federal Official, at the contact... information regarding the ACICBL should contact Dr. Joan Weiss, Designated Federal Official within the Bureau... request to the following address: Dr. Joan Weiss, Designated Federal Official, Bureau of Health...

  12. Content and Design Features of Academic Health Sciences Libraries' Home Pages.

    PubMed

    McConnaughy, Rozalynd P; Wilson, Steven P

    2018-01-01

    The goal of this content analysis was to identify commonly used content and design features of academic health sciences library home pages. After developing a checklist, data were collected from 135 academic health sciences library home pages. The core components of these library home pages included a contact phone number, a contact email address, an Ask-a-Librarian feature, the physical address listed, a feedback/suggestions link, subject guides, a discovery tool or database-specific search box, multimedia, social media, a site search option, a responsive web design, and a copyright year or update date.

  13. Automated contact angle estimation for three-dimensional X-ray microtomography data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Klise, Katherine A.; Moriarty, Dylan; Yoon, Hongkyu

    2015-11-10

    Multiphase flow in capillary regimes is a fundamental process in a number of geoscience applications. The ability to accurately define wetting characteristics of porous media can have a large impact on numerical models. In this paper, a newly developed automated three-dimensional contact angle algorithm is described and applied to high-resolution X-ray microtomography data from multiphase bead pack experiments with varying wettability characteristics. The algorithm calculates the contact angle by finding the angle between planes fit to each solid/fluid and fluid/fluid interface in the region surrounding each solid/fluid/fluid contact point. Results show that the algorithm is able to reliably compute contactmore » angles using the experimental data. The in situ contact angles are typically larger than flat surface laboratory measurements using the same material. Furthermore, wetting characteristics in mixed-wet systems also change significantly after displacement cycles.« less

  14. FASTSIM2: a second-order accurate frictional rolling contact algorithm

    NASA Astrophysics Data System (ADS)

    Vollebregt, E. A. H.; Wilders, P.

    2011-01-01

    In this paper we consider the frictional (tangential) steady rolling contact problem. We confine ourselves to the simplified theory, instead of using full elastostatic theory, in order to be able to compute results fast, as needed for on-line application in vehicle system dynamics simulation packages. The FASTSIM algorithm is the leading technology in this field and is employed in all dominant railway vehicle system dynamics packages (VSD) in the world. The main contribution of this paper is a new version "FASTSIM2" of the FASTSIM algorithm, which is second-order accurate. This is relevant for VSD, because with the new algorithm 16 times less grid points are required for sufficiently accurate computations of the contact forces. The approach is based on new insights in the characteristics of the rolling contact problem when using the simplified theory, and on taking precise care of the contact conditions in the numerical integration scheme employed.

  15. Low resistance Ohmic contact to p-type crystalline silicon via nitrogen-doped copper oxide films

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Xinyu, E-mail: xinyu.zhang@anu.edu.au; Wan, Yimao; Bullock, James

    2016-08-01

    This work explores the application of transparent nitrogen doped copper oxide (CuO{sub x}:N) films deposited by reactive sputtering to create hole-selective contacts for p-type crystalline silicon (c-Si) solar cells. It is found that CuO{sub x}:N sputtered directly onto crystalline silicon is able to form an Ohmic contact. X-ray photoelectron spectroscopy and Raman spectroscopy measurements are used to characterise the structural and physical properties of the CuO{sub x}:N films. Both the oxygen flow rate and the substrate temperature during deposition have a significant impact on the film composition, as well as on the resulting contact resistivity. After optimization, a low contactmore » resistivity of ∼10 mΩ cm{sup 2} has been established. This result offers significant advantages over conventional contact structures in terms of carrier transport and device fabrication.« less

  16. 76 FR 43712 - Notice of Inventory Completion: U.S. Department of the Interior, Bureau of Indian Affairs...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-21

    ... Science and Industry at the address below by August 22, 2011. ADDRESSES: Lori Erickson, Curator, Oregon... the human remains should contact Lori Erickson, Curator, Oregon Museum of Science and Industry, 1945...

  17. 77 FR 48538 - Notice of Inventory Completion: State Historical Society of Wisconsin, Madison, WI

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-14

    ... Historical Society of Wisconsin at the address below by September 13, 2012. ADDRESSES: Jennifer Kolb... Indian tribe that believes it satisfies the criteria in 43 CFR 10.11(c)(1) should contact Jennifer Kolb...

  18. Contact engineering for 2D materials and devices.

    PubMed

    Schulman, Daniel S; Arnold, Andrew J; Das, Saptarshi

    2018-05-08

    Over the past decade, the field of two-dimensional (2D) layered materials has surged, promising a new platform for studying diverse physical phenomena that are scientifically intriguing and technologically relevant. Contacts are the communication links between these 2D materials and the three-dimensional world for probing and harnessing their exquisite electronic properties. However, fundamental challenges related to contacts often limit the ultimate performance and potential of 2D materials and devices. This article provides a comprehensive overview of the basic understanding and importance of contacts to 2D materials and various strategies for engineering and improving them. In particular, we elucidate the phenomenon of Fermi level pinning at the metal/2D contact interface, the Schottky versus Ohmic nature of the contacts and various contact engineering approaches including interlayer contacts, phase engineered contacts, and basal versus edge plane contacts, among others. Finally, we also discuss some of the relatively under-addressed and unresolved issues, such as contact scaling, and conclude with a future outlook.

  19. Estimating the effect of lay knowledge and prior contact with pulmonary TB patients, on health-belief model in a high-risk pulmonary TB transmission population.

    PubMed

    Zein, Rizqy Amelia; Suhariadi, Fendy; Hendriani, Wiwin

    2017-01-01

    The research aimed to investigate the effect of lay knowledge of pulmonary tuberculosis (TB) and prior contact with pulmonary TB patients on a health-belief model (HBM) as well as to identify the social determinants that affect lay knowledge. Survey research design was conducted, where participants were required to fill in a questionnaire, which measured HBM and lay knowledge of pulmonary TB. Research participants were 500 residents of Semampir, Asemrowo, Bubutan, Pabean Cantian, and Simokerto districts, where the risk of pulmonary TB transmission is higher than other districts in Surabaya. Being a female, older in age, and having prior contact with pulmonary TB patients significantly increase the likelihood of having a higher level of lay knowledge. Lay knowledge is a substantial determinant to estimate belief in the effectiveness of health behavior and personal health threat. Prior contact with pulmonary TB patients is able to explain the belief in the effectiveness of a health behavior, yet fails to estimate participants' belief in the personal health threat. Health authorities should prioritize males and young people as their main target groups in a pulmonary TB awareness campaign. The campaign should be able to reconstruct people's misconception about pulmonary TB, thereby bringing around the health-risk perception so that it is not solely focused on improving lay knowledge.

  20. Cell studies of hybridized carbon nanofibers containing bioactive glass nanoparticles using bone mesenchymal stromal cells

    NASA Astrophysics Data System (ADS)

    Zhang, Xiu-Rui; Hu, Xiao-Qing; Jia, Xiao-Long; Yang, Li-Ka; Meng, Qing-Yang; Shi, Yuan-Yuan; Zhang, Zheng-Zheng; Cai, Qing; Ao, Yin-Fang; Yang, Xiao-Ping

    2016-12-01

    Bone regeneration required suitable scaffolding materials to support the proliferation and osteogenic differentiation of bone-related cells. In this study, a kind of hybridized nanofibrous scaffold material (CNF/BG) was prepared by incorporating bioactive glass (BG) nanoparticles into carbon nanofibers (CNF) via the combination of BG sol-gel and polyacrylonitrile (PAN) electrospinning, followed by carbonization. Three types (49 s, 68 s and 86 s) of BG nanoparticles were incorporated. To understand the mechanism of CNF/BG hybrids exerting osteogenic effects, bone marrow mesenchymal stromal cells (BMSCs) were cultured directly on these hybrids (contact culture) or cultured in transwell chambers in the presence of these materials (non-contact culture). The contributions of ion release and contact effect on cell proliferation and osteogenic differentiation were able to be correlated. It was found that the ionic dissolution products had limited effect on cell proliferation, while they were able to enhance osteogenic differentiation of BMSCs in comparison with pure CNF. Differently, the proliferation and osteogenic differentiation were both significantly promoted in the contact culture. In both cases, CNF/BG(68 s) showed the strongest ability in influencing cell behaviors due to its fastest release rate of soluble silicium-relating ions. The synergistic effect of CNF and BG would make CNF/BG hybrids promising substrates for bone repairing.

  1. Optimizing pentacene thin-film transistor performance: Temperature and surface condition induced layer growth modification.

    PubMed

    Lassnig, R; Hollerer, M; Striedinger, B; Fian, A; Stadlober, B; Winkler, A

    2015-11-01

    In this work we present in situ electrical and surface analytical, as well as ex situ atomic force microscopy (AFM) studies on temperature and surface condition induced pentacene layer growth modifications, leading to the selection of optimized deposition conditions and entailing performance improvements. We prepared p ++ -silicon/silicon dioxide bottom-gate, gold bottom-contact transistor samples and evaluated the pentacene layer growth for three different surface conditions (sputtered, sputtered + carbon and unsputtered + carbon) at sample temperatures during deposition of 200 K, 300 K and 350 K. The AFM investigations focused on the gold contacts, the silicon dioxide channel region and the highly critical transition area. Evaluations of coverage dependent saturation mobilities, threshold voltages and corresponding AFM analysis were able to confirm that the first 3-4 full monolayers contribute to the majority of charge transport within the channel region. At high temperatures and on sputtered surfaces uniform layer formation in the contact-channel transition area is limited by dewetting, leading to the formation of trenches and the partial development of double layer islands within the channel region instead of full wetting layers. By combining the advantages of an initial high temperature deposition (well-ordered islands in the channel) and a subsequent low temperature deposition (continuous film formation for low contact resistance) we were able to prepare very thin (8 ML) pentacene transistors of comparably high mobility.

  2. ER-driven membrane contact sites: Evolutionary conserved machineries for stress response and autophagy regulation?

    PubMed Central

    Molino, Diana; Nascimbeni, Anna Chiara; Giordano, Francesca; Codogno, Patrice

    2017-01-01

    ABSTRACT Endoplasmic Reticulum (ER), spreading in the whole cell cytoplasm, is a central player in eukaryotic cell homeostasis, from plants to mammals. Beside crucial functions, such as membrane lipids and proteins synthesis and outward transport, the ER is able to connect to virtually every endomembrane compartment by specific tethering molecular machineries, which enables the establishment of membrane-membrane contact sites. ER-mitochondria contact sites have been shown to be involved in autophagosome biogenesis, the main organelle of the autophagy degradation pathway. More recently we demonstrated that also ER-plasma membrane contact sites are sites for autophagosomes assembly, suggesting that more generally ER-organelles contacts are involved in autophagy and organelle biogenesis. Here we aim to discuss the functioning of ER-driven contact sites in mammals and plants and more in particular emphasize on their recently highlighted function in autophagy to finally conclude on some key questions that may be useful for further research in the field. PMID:29259731

  3. Dynamic Contact Angle at the Nanoscale: A Unified View.

    PubMed

    Lukyanov, Alex V; Likhtman, Alexei E

    2016-06-28

    Generation of a dynamic contact angle in the course of wetting is a fundamental phenomenon of nature. Dynamic wetting processes have a direct impact on flows at the nanoscale, and therefore, understanding them is exceptionally important to emerging technologies. Here, we reveal the microscopic mechanism of dynamic contact angle generation. It has been demonstrated using large-scale molecular dynamics simulations of bead-spring model fluids that the main cause of local contact angle variations is the distribution of microscopic force acting at the contact line region. We were able to retrieve this elusive force with high accuracy. It has been directly established that the force distribution can be solely predicted on the basis of a general friction law for liquid flow at solid surfaces by Thompson and Troian. The relationship with the friction law provides both an explanation of the phenomenon of dynamic contact angle and a methodology for future predictions. The mechanism is intrinsically microscopic, universal, and irreducible and is applicable to a wide range of problems associated with wetting phenomena.

  4. Analysis of contact zones from whole field isochromatics using reflection photoelasticity

    NASA Astrophysics Data System (ADS)

    Hariprasad, M. P.; Ramesh, K.

    2018-06-01

    This paper discusses the method for evaluating the unknown contact parameters by post processing the whole field fringe order data obtained from reflection photoelasticity in a nonlinear least squares sense. Recent developments in Twelve Fringe Photoelasticity (TFP) for fringe order evaluation from single isochromatics is utilized for the whole field fringe order evaluation. One of the issues in using TFP for reflection photoelasticity is the smudging of isochromatic data at the contact zone. This leads to error in identifying the origin of contact, which is successfully addressed by implementing a semi-automatic contact point refinement algorithm. The methodologies are initially verified for benchmark problems and demonstrated for two application problems of turbine blade and sheet pile contacting interfaces.

  5. An alternative method of fabricating sub-micron resolution masks using excimer laser ablation

    NASA Astrophysics Data System (ADS)

    Hayden, C. J.; Eijkel, J. C. T.; Dalton, C.

    2004-06-01

    In the work presented here, an excimer laser micromachining system has been used successfully to fabricate high-resolution projection and contact masks. The contact masks were subsequently used to produce chrome-gold circular ac electro-osmotic pump (cACEOP) microelectrode arrays on glass substrates, using a conventional contact photolithography process. The contact masks were produced rapidly (~15 min each) and were found to be accurate to sub-micron resolution, demonstrating an alternative route for mask fabrication. Laser machined masks were also used in a laser-projection system, demonstrating that such fabrication techniques are also suited to projection lithography. The work addresses a need for quick reproduction of high-resolution contact masks, given their rapid degradation when compared to non-contact masks.

  6. Improving contact layer patterning using SEM contour based etch model

    NASA Astrophysics Data System (ADS)

    Weisbuch, François; Lutich, Andrey; Schatz, Jirka; Hertzsch, Tino; Moll, Hans-Peter

    2016-10-01

    The patterning of the contact layer is modulated by strong etch effects that are highly dependent on the geometry of the contacts. Such litho-etch biases need to be corrected to ensure a good pattern fidelity. But aggressive designs contain complex shapes that can hardly be compensated with etch bias table and are difficult to characterize with standard CD metrology. In this work we propose to implement a model based etch compensation method able to deal with any contact configuration. With the help of SEM contours, it was possible to get reliable 2D measurements particularly helpful to calibrate the etch model. The selections of calibration structures was optimized in combination with model form to achieve an overall errRMS of 3nm allowing the implementation of the model in production.

  7. Generation and Computerized Simulation of Meshing and Contact of Modified Involute Helical Gears

    NASA Technical Reports Server (NTRS)

    Litvin, Faydor L.; Chen, Ningxin; Lu, Jian

    1995-01-01

    The design and generation of modified involute helical gears that have a localized and stable bearing contact, and reduced noise and vibration characteristics are described. The localization of the bearing contact is achieved by the mismatch of the two generating surfaces that are used for generation of the pinion and the gear. The reduction of noise and vibration will be achieved by application of a parabolic function of transmission errors that is able to absorb the almost linear function of transmission errors caused by gear misalignment. The meshing and contact of misaligned gear drives can be analyzed by application of computer programs that have been developed. The computations confirmed the effectiveness of the proposed modification of the gear geometry. A numerical example that illustrates the developed theory is provided.

  8. Beta Atomic Contacts: Identifying Critical Specific Contacts in Protein Binding Interfaces

    PubMed Central

    Liu, Qian; Kwoh, Chee Keong; Hoi, Steven C. H.

    2013-01-01

    Specific binding between proteins plays a crucial role in molecular functions and biological processes. Protein binding interfaces and their atomic contacts are typically defined by simple criteria, such as distance-based definitions that only use some threshold of spatial distance in previous studies. These definitions neglect the nearby atomic organization of contact atoms, and thus detect predominant contacts which are interrupted by other atoms. It is questionable whether such kinds of interrupted contacts are as important as other contacts in protein binding. To tackle this challenge, we propose a new definition called beta (β) atomic contacts. Our definition, founded on the β-skeletons in computational geometry, requires that there is no other atom in the contact spheres defined by two contact atoms; this sphere is similar to the van der Waals spheres of atoms. The statistical analysis on a large dataset shows that β contacts are only a small fraction of conventional distance-based contacts. To empirically quantify the importance of β contacts, we design βACV, an SVM classifier with β contacts as input, to classify homodimers from crystal packing. We found that our βACV is able to achieve the state-of-the-art classification performance superior to SVM classifiers with distance-based contacts as input. Our βACV also outperforms several existing methods when being evaluated on several datasets in previous works. The promising empirical performance suggests that β contacts can truly identify critical specific contacts in protein binding interfaces. β contacts thus provide a new model for more precise description of atomic organization in protein quaternary structures than distance-based contacts. PMID:23630569

  9. In vivo performance of a drug-eluting contact lens to treat glaucoma for a month

    PubMed Central

    Ciolino, Joseph B.; Stefanescu, Cristina F.; Ross, Amy E.; Salvador-Culla, Borja; Cortez, Priscila; Ford, Eden M.; Wymbs, Kate A.; Sprague, Sarah L.; Mascoop, Daniel R.; Rudina, Shireen S.; Trauger, Sunia A.; Cade, Fabiano; Kohane, Daniel S.

    2013-01-01

    For nearly half a century, contact lenses have been proposed as a means of ocular drug delivery, but achieving controlled drug release has been a significant challenge. We have developed a drug-eluting contact lens designed for prolonged delivery of latanoprost for the treatment of glaucoma, the leading cause of irreversible blindness worldwide. Latanoprost-eluting contact lenses were created by encapsulating latanoprost–poly(lactic-co-glycolic acid) films in methafilcon by ultraviolet light polymerization. In vitro and in vivo studies showed an early burst of drug release followed by sustained release for one month. Contact lenses containing thicker drug–polymer films demonstrated released a greater amount of drug after the initial burst. In vivo, single contact lenses were able to achieve, for at least one month, latanoprost concentrations in the aqueous humor that were comparable to those achieved with topical latanoprost solution, the current first-line treatment for glaucoma. The lenses appeared safe in cell culture and animal studies. This contact lens design can potentially be used as a treatment for glaucoma and as a platform for other ocular drug delivery applications. PMID:24094935

  10. 76 FR 17147 - Proposed Information Collection; Monitoring Recovered Species After Delisting-American Peregrine...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-28

    ... additional information about this IC, contact Hope Grey at the e-mail address in ADDRESSES or at 703-358-2482... recovered species be conducted for not less than 5 years, the life history of American peregrine falcons is...

  11. 75 FR 21253 - Privacy Act of 1974; System of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-23

    ... Processing (In/Out Proc): Soldiers' personal cell phone number, home telephone number, personal e-mail address, mailing/home address, emergency contact, mother's maiden name, spouse information, and child information. Transition Processing (TRANSPROC): Soldiers' personal cell phone number, home telephone number...

  12. A Framework for Resource and Execution Management

    DTIC Science & Technology

    2011-06-01

    Topic( s ): Topic 4: Information and Knowledge Exploitation Name of Author( s ): Abdeslem Boukhtouta Mohamad Allouche Point of Contact...AUTHOR( S ) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS(ES) Defence R&D Canada - Valcartier...2459 Pie-XI North,Qu?c, QC, CANADA, G3J 1X5, 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME( S ) AND ADDRESS(ES) 10

  13. Unraveling sexual associations in contact and noncontact child sex offenders using the single category - implicit association test.

    PubMed

    Hempel, I S; Buck, N M L; Goethals, K R; van Marle, H J C

    2013-10-01

    Previous studies found associations between children and sex in child sex offenders (CSOs) using the Implicit Association Test (IAT). We used a modification of this task, the Single Category-Implicit Association Test (SC-IAT) to unravel child-sex associations in CSOs. Using the SC-IAT, we were able to test whether CSOs indeed hold stronger child-sex associations relative to adult-sex associations, compared to adult sex offenders and nonoffenders. Furthermore, we examined whether contact CSOs differed from noncontact CSOs in their child-sex associations. The hypothesis that CSOs would have stronger child-sex associations, relative to their adult-sex associations, than adult sex offenders and nonoffenders was confirmed. No difference between contact CSOs and noncontact CSOs was found. Although the Sex SC-IAT was able to distinguish CSOs from nonoffenders, the sensitivity and specificity of the test was poor (AUC of .65) and needs refinement. The results of this study support the existence of a child-sex association as a distinctive characteristic of CSOs. These findings are discussed in the context of theories on deviant cognitions in CSOs and risk for sexual offending.

  14. Screening new cancer patients for psychological distress using the hospital anxiety and depression scale.

    PubMed

    Sellick, Scott M; Edwardson, Alan D

    2007-06-01

    The diagnosis of a life-threatening illness creates immediate psychosocial distress for the patient and his or her family. The threat is real and the rational response is to be afraid. We need to be reaching out to patients and their families and not waiting for crises. The responsibility remains with the healthcare system and psychosocial healthcare professionals to identify those who are in most need. Psychological distress is something that can be relatively easily measured and responded to when psychosocial oncology healthcare professionals are immediately available to address those needs. This paper describes the process used to gather this information, how that information has been used by the psychosocial clinicians in the Supportive Care programme, and what we have learned, in terms of a retrospective data analysis, about our patient population. At the Cancer Centre in Thunder Bay, Ontario, Canada new cancer patients complete the HADS on the day of their first appointment. Since October 2000 we have collected baseline psychological distress data for 3,035 new cancer patients who fully completed all 14 items on the HADS. Of those, 781 patients, or 25.7%, scored above cut-off points and were given a telephone call. We were able to contact 607 (or 77.7%) of these patients. Five hundred and eight (or 83.7%) of those contacted made, and subsequently attended, one or more appointments with a psychosocial counsellor. Copyright 2006 John Wiley & Sons, Ltd.

  15. 78 FR 1212 - Agency Information Collection Activities: Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-08

    ... information collection for the proper performance of the agency's functions; (2) the accuracy of the estimated... gain provider feedback regarding their satisfaction with their MACs, we need to be able to contact the...

  16. General framework for dynamic large deformation contact problems based on phantom-node X-FEM

    NASA Astrophysics Data System (ADS)

    Broumand, P.; Khoei, A. R.

    2018-04-01

    This paper presents a general framework for modeling dynamic large deformation contact-impact problems based on the phantom-node extended finite element method. The large sliding penalty contact formulation is presented based on a master-slave approach which is implemented within the phantom-node X-FEM and an explicit central difference scheme is used to model the inertial effects. The method is compared with conventional contact X-FEM; advantages, limitations and implementational aspects are also addressed. Several numerical examples are presented to show the robustness and accuracy of the proposed method.

  17. Surrogate modeling of deformable joint contact using artificial neural networks.

    PubMed

    Eskinazi, Ilan; Fregly, Benjamin J

    2015-09-01

    Deformable joint contact models can be used to estimate loading conditions for cartilage-cartilage, implant-implant, human-orthotic, and foot-ground interactions. However, contact evaluations are often so expensive computationally that they can be prohibitive for simulations or optimizations requiring thousands or even millions of contact evaluations. To overcome this limitation, we developed a novel surrogate contact modeling method based on artificial neural networks (ANNs). The method uses special sampling techniques to gather input-output data points from an original (slow) contact model in multiple domains of input space, where each domain represents a different physical situation likely to be encountered. For each contact force and torque output by the original contact model, a multi-layer feed-forward ANN is defined, trained, and incorporated into a surrogate contact model. As an evaluation problem, we created an ANN-based surrogate contact model of an artificial tibiofemoral joint using over 75,000 evaluations of a fine-grid elastic foundation (EF) contact model. The surrogate contact model computed contact forces and torques about 1000 times faster than a less accurate coarse grid EF contact model. Furthermore, the surrogate contact model was seven times more accurate than the coarse grid EF contact model within the input domain of a walking motion. For larger input domains, the surrogate contact model showed the expected trend of increasing error with increasing domain size. In addition, the surrogate contact model was able to identify out-of-contact situations with high accuracy. Computational contact models created using our proposed ANN approach may remove an important computational bottleneck from musculoskeletal simulations or optimizations incorporating deformable joint contact models. Copyright © 2015 IPEM. Published by Elsevier Ltd. All rights reserved.

  18. Surrogate Modeling of Deformable Joint Contact using Artificial Neural Networks

    PubMed Central

    Eskinazi, Ilan; Fregly, Benjamin J.

    2016-01-01

    Deformable joint contact models can be used to estimate loading conditions for cartilage-cartilage, implant-implant, human-orthotic, and foot-ground interactions. However, contact evaluations are often so expensive computationally that they can be prohibitive for simulations or optimizations requiring thousands or even millions of contact evaluations. To overcome this limitation, we developed a novel surrogate contact modeling method based on artificial neural networks (ANNs). The method uses special sampling techniques to gather input-output data points from an original (slow) contact model in multiple domains of input space, where each domain represents a different physical situation likely to be encountered. For each contact force and torque output by the original contact model, a multi-layer feed-forward ANN is defined, trained, and incorporated into a surrogate contact model. As an evaluation problem, we created an ANN-based surrogate contact model of an artificial tibiofemoral joint using over 75,000 evaluations of a fine-grid elastic foundation (EF) contact model. The surrogate contact model computed contact forces and torques about 1000 times faster than a less accurate coarse grid EF contact model. Furthermore, the surrogate contact model was seven times more accurate than the coarse grid EF contact model within the input domain of a walking motion. For larger input domains, the surrogate contact model showed the expected trend of increasing error with increasing domain size. In addition, the surrogate contact model was able to identify out-of-contact situations with high accuracy. Computational contact models created using our proposed ANN approach may remove an important computational bottleneck from musculoskeletal simulations or optimizations incorporating deformable joint contact models. PMID:26220591

  19. Persistence and elimination of human norovirus in food and on food contact surfaces: a critical review

    USDA-ARS?s Scientific Manuscript database

    This critical review addresses the persistence of human norovirus (NoV) in water, shellfish, processed meats, soils and organic wastes; on berries, herbs, vegetables, fruits and salads; and on food contact surfaces. The review focuses on studies using NoV; information from studies involving only su...

  20. 75 FR 51985 - Federal Advisory Committee; Advisory Council on Dependents' Education (ACDE)

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-24

    ..., Germany. DATES: The meetings will be held: 1. Friday, November 12, 2010, from 8 a.m. to 11 a.m. (Eastern... Time), in Riedstadt, Germany. ADDRESSES: The meetings will be held: 1. Arlington--4040 North Fairfax..., Germany 64560. FOR FURTHER INFORMATION CONTACT: Committee's Point of Contact: Ms. Leesa Rompre, tel. (703...

  1. Contact Us

    Science.gov Websites

    Naval History Contact Us Command Addresses (SNDL) FAQ Leadership Secretary of the Navy Under Secretary Chiefs of Staff Defense.gov U.S. Army U.S. Air Force U.S. Marine Corps U.S. Coast Guard Naval History https://awards.navy.mil Naval Heritage And History Command http://www.history.navy.mil/about-us

  2. 75 FR 11192 - Proposed Information Collection; OMB Control Number 1018-0094; Federal Fish and Wildlife Permit...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... them by May 10, 2010. ADDRESSES: Send your comments on the IC to Hope Grey, Information Collection... (mail); or hope_ grey@fws.gov (e-mail). FOR FURTHER INFORMATION CONTACT: To request additional information about this IC, contact Hope Grey by mail or e- [[Page 11193

  3. Dialect Contact among Spanish-Speaking Children in Los Angeles

    ERIC Educational Resources Information Center

    Villarreal, Belen MacGregor

    2014-01-01

    As an immigration hub for a diverse group of Spanish speakers, Los Angeles lends itself to research on dialect contact and leveling. Studies regarding the Spanish spoken by natives of Los Angeles reveal considerable homogeneity with respect to pronunciation, vocabulary and terms of address. This uniformity is notable because two different dialect…

  4. 77 FR 22799 - Tribal Consultation Sessions-Administrative Organizational Assessment Draft Report...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-17

    ...) and the Department of the Interior (DOI) to improve American Indian and Alaska Native education. The... proposed MOU between DOI and ED received by close of business on June 15, 2012. ADDRESSES: See the..., Washington, DC 20240. FOR FURTHER INFORMATION CONTACT: For the proposed MOU between ED and DOI, contact...

  5. 75 FR 18837 - Office of Public Health and Science, Office of Minority Health; Privacy Act of 1974; Report of a...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-13

    ... collected on members of the general public, health professionals, faculty of academic institutions, students... peers on healthy living and pre-conception care. 5. Organizational Databases: Business contact... to work. 3. Organizational Databases: Name of organization and key contact person, business address...

  6. 78 FR 74188 - Sunshine Act Meetings Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-10

    ... Casks (Public Meeting) (Contact: Kevin Witt, 301-415-2145) This meeting will be Web cast live at the Web... Weather Events (Public Meeting) (Contact: George Wilson, 301-415-1711) This meeting will be Web cast live... will be Web cast live at the Web address-- http://www.nrc.gov/ . Week of January 13, 2014--Tentative...

  7. 49 CFR 1105.11 - Transmittal letter for Applicant's Report.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... proposal, please contact our representative directly. Our representative in this matter is (name) who may be contacted by telephone at (telephone number) or by mail at (address). (Complimentary close) (Name and title of author of letter) [56 FR 36105, July 31, 1991, as amended at 58 FR 44619, Aug. 24, 1993...

  8. 49 CFR 1105.11 - Transmittal letter for Applicant's Report.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... proposal, please contact our representative directly. Our representative in this matter is (name) who may be contacted by telephone at (telephone number) or by mail at (address). (Complimentary close) (Name and title of author of letter) [56 FR 36105, July 31, 1991, as amended at 58 FR 44619, Aug. 24, 1993...

  9. Ion Beam Processing of Diamond

    DTIC Science & Technology

    1990-05-07

    Diamond structure. We can make ohmic contacts to silicon . If we could tailor the structure from Si to Si. C,-, to diamond, we should be able to form a low...func- ricr injection. Refractory metals such as tantalum. tung- tion of contact spacing. Extrapolation of the data to zero sten , or titanium have also...layer of the diamond could be miade n-type gallium nitride. and silicon carbide.- Mater. Sci. Fng.. vol. 91, pp.77-104.1(998. with a five to six orders

  10. Effect of pentacene/Ag anode buffer and UV-ozone treatment on durability of small-molecule organic solar cells

    NASA Astrophysics Data System (ADS)

    Inagaki, S.; Sueoka, S.; Harafuji, K.

    2017-06-01

    Three surface modifications of indium tin oxide (ITO) are experimentally investigated to improve the performance of small-molecule organic solar cells (OSCs) with an ITO/anode buffer layer (ABL)/copper phthalocyanine (CuPc)/fullerene/bathocuproine/Ag structure. An ultrathin Ag ABL and ultraviolet (UV)-ozone treatment of ITO independently improve the durability of OSCs against illumination stress. The thin pentacene ABL provides good ohmic contact between the ITO and the CuPc layer, thereby producing a large short-circuit current. The combined use of the abovementioned three modifications collectively achieves both better initial performance and durability against illumination stress.

  11. Numerical Simulation of Dynamic Contact Angles and Contact Lines in Multiphase Flows using Level Set Method

    NASA Astrophysics Data System (ADS)

    Pendota, Premchand

    Many physical phenomena and industrial applications involve multiphase fluid flows and hence it is of high importance to be able to simulate various aspects of these flows accurately. The Dynamic Contact Angles (DCA) and the contact lines at the wall boundaries are a couple of such important aspects. In the past few decades, many mathematical models were developed for predicting the contact angles of the inter-face with the wall boundary under various flow conditions. These models are used to incorporate the physics of DCA and contact line motion in numerical simulations using various interface capturing/tracking techniques. In the current thesis, a simple approach to incorporate the static and dynamic contact angle boundary conditions using the level set method is developed and implemented in multiphase CFD codes, LIT (Level set Interface Tracking) (Herrmann (2008)) and NGA (flow solver) (Desjardins et al (2008)). Various DCA models and associated boundary conditions are reviewed. In addition, numerical aspects such as the occurrence of a stress singularity at the contact lines and grid convergence of macroscopic interface shape are dealt with in the context of the level set approach.

  12. Intergroup contact and team functioning among nursing students: the mediation role of intergroup anxiety.

    PubMed

    Marletta, Giuseppe; Sarli, Leopoldo; Caricati, Luca; Mancini, Tiziana

    2017-07-18

    The improvement of team effectivity is one of the main concerns for healthcare organizations. Moreover, healthcare organizations must cope with increasing multicultural composition of both workforce and patients. The intergroup contact theory suggests that frequent and positive face-to-face contact among professionals or students with different cultural heritage can help to reach both increasing team effectiveness and adequate care in a multicultural setting. The aim was then to verify whether intergroup contact during practical training would decrease intergroup anxiety and then increase team functioning. A cross-sectional design was used in which a questionnaire was delivered to 83 nursing students. According to the intergroup contact theory, frequent and positive contact with non-native professionals decreased the intergroup anxiety which, in turn, increased prejudice and, more importantly, decreased team functioning. Moreover, intergroup anxiety showed a complete mediation effect on the relations between intergroup contact during practical training and both negative attitude toward immigrants and team functioning. Intergroup contact with non-native professionals or students during practical training is able to indirectly decrease prejudice and improve team functioning by lowering the anxiety that is aroused by encounter with non-native individuals.

  13. Exemplary Programs in Secondary School Biology.

    ERIC Educational Resources Information Center

    McComas, William F.; Penick, John E.

    1989-01-01

    Summarizes 10 exemplary programs which address topics on individualized biology, a modified team approach, limnology, physical anthropology, the relevance of biology to society, ecology, and health. Provides names and addresses of contact persons for further information. Units cover a broad range of abilities and activities. (RT)

  14. Coupling of Armchair and Zigzag Tubes to a Free Electron Metal

    NASA Technical Reports Server (NTRS)

    Anantram, M. P.; Biegel, Bryan (Technical Monitor)

    2001-01-01

    The effect of nanotube chirality is of prime importance in determining its electronic properties. We address the issue of how chirality affects the coupling of a nanotube to metal contacts. We model coupling of armchair and zigzag nanotubes to metal contacts, in both the side- and end-contacted geometries. In the side-contacted geometry, the coupling of armchair and metallic-zigzag nanotubes to a free electron metal are significantly different. Namely, it is possible to drive a larger current through a metallic-zigzag nanotube. The predicted difference holds good when both (a) the entire circumference and (b) only a finite sector of the nanotube makes contact to the metal electrode. It might be possible to observe the predicted difference between armchair and zigzag nanotubes using gold contacts.

  15. Dynamic nuclear polarization at high Landau levels in a quantum point contact

    NASA Astrophysics Data System (ADS)

    Fauzi, M. H.; Noorhidayati, A.; Sahdan, M. F.; Sato, K.; Nagase, K.; Hirayama, Y.

    2018-05-01

    We demonstrate a way to polarize and detect nuclear spin in a gate-defined quantum point contact operating at high Landau levels. Resistively detected nuclear magnetic resonance (RDNMR) can be achieved up to the fifth Landau level and at a magnetic field lower than 1 T. We are able to retain the RDNMR signals in a condition where the spin degeneracy of the first one-dimensional (1D) subband is still preserved. Furthermore, the effects of orbital motion on the first 1D subband can be made smaller than those due to electrostatic confinement. This developed RDNMR technique is a promising means to study electronic states in a quantum point contact near zero magnetic field.

  16. Master-slave robotic system for needle indentation and insertion.

    PubMed

    Shin, Jaehyun; Zhong, Yongmin; Gu, Chengfan

    2017-12-01

    Bilateral control of a master-slave robotic system is a challenging issue in robotic-assisted minimally invasive surgery. It requires the knowledge on contact interaction between a surgical (slave) robot and soft tissues. This paper presents a master-slave robotic system for needle indentation and insertion. This master-slave robotic system is able to characterize the contact interaction between the robotic needle and soft tissues. A bilateral controller is implemented using a linear motor for robotic needle indentation and insertion. A new nonlinear state observer is developed to online monitor the contact interaction with soft tissues. Experimental results demonstrate the efficacy of the proposed master-slave robotic system for robotic needle indentation and needle insertion.

  17. Regional District Attorney's Offices - Alaska Department of Law

    Science.gov Websites

    not provide legal advice to private citizens or organizations. Please contact an attorney if you need legal advice. The Alaska Lawyer Referral Service or your local bar association may be able to assist you

  18. 78 FR 78472 - Registration and Financial Security Requirements for Brokers of Property and Freight Forwarders...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-26

    ... address, an email address, or a phone number in the body of your document so that FMCSA can contact you if... Agency published a final rule amending 49 CFR part 387 to set a minimum $75,000 surety bond/trust fund.... ADDRESSES: You may submit comments, identified by docket number FMCSA- 2013-0513, by any of the following...

  19. 18 CFR 157.6 - Applications; general requirements.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... the pamphlet and indicate its availability at the Commission's Internet address; (iii) A description... local or toll-free phone number and a name of a specific person to contact who is knowledgeable about... Internet address and the telephone number for the Commission's Office of External Affairs; and (vi...

  20. 78 FR 30868 - New England Fishery Management Council; Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-23

    .... ADDRESSES: Meeting address: The meeting will be held at the Providence Biltmore, 11 Dorrance Street... Management Council, 50 Water Street, Mill 2, Newburyport, MA 01950. FOR FURTHER INFORMATION CONTACT: Thomas A... Deputy Director, Office of Sustainable Fisheries, National Marine Fisheries Service. [FR Doc. 2013-12264...

  1. SARD Course Registration Form | Center for Cancer Research

    Cancer.gov

    Mandatory responses are marked by an asterisk (*). A confirmation e-mail will be sent to the address listed in the "E-mail Address" field upon completion and submission of the form. Questions? E-mail Dr. Terry Moody or contact him by phone at (240) 276-7785.

  2. Analysis of the Small Business Administration 8(a) Business Development Program

    DTIC Science & Technology

    2015-06-01

    Parent DUNS Number: Address, line 1: 9656 E Empress Ave Address, line 2: City: Mesa State: AZ Zip: 85208-3156 Phone Number: 480-220-9226 Fax...products): https://www.imgnetworks.com Contact Person: RAY RODRIGUEZ County Code (3 digit): 073 Congressional District: 51 Metropolitan

  3. Pesticide Registration Manual: How to Report Changes to Company Name or Address

    EPA Pesticide Factsheets

    Any changes to the official address, withdrawal of an existing agent, appointment of a new agent or changes to any of the contact information for the company or its agent must be reported to EPA. Find out more about how to do this.

  4. Millennials and Their Parents: Implications of the New Young Adulthood for Midlife Adults

    PubMed Central

    Fingerman, Karen L

    2017-01-01

    Abstract The period of young adulthood has transformed dramatically over the past few decades. Today, scholars refer to “emerging adulthood” and “transitions to adulthood” to describe adults in their 20s. Prolonged youth has brought concomitant prolonged parenthood. This article addresses 3 areas of change in parent/child ties, increased (a) contact between generations, (b) support from parents to grown children as well as coresidence and (c) affection between the generations. We apply the Multidimensional Intergenerational Support Model (MISM) to explain these changes, considering societal (e.g., economic, technological), cultural, family demographic (e.g., fertility, stepparenting), relationship, and psychological (normative beliefs, affection) factors. Several theoretical perspectives (e.g., life course theory, family systems theory) suggest that these changes may have implications for the midlife parents’ well-being. For example, parents may incur deleterious effects from (a) grown children’s problems or (b) their own normative beliefs that offspring should be independent. Parents may benefit via opportunities for generativity with young adult offspring. Furthermore, current patterns may affect future parental aging. As parents incur declines of late life, they may be able to turn to caregivers with whom they have intimate bonds. Alternately, parents may be less able to obtain such care due to demographic changes involving grown children raising their own children later or who have never fully launched. It is important to consider shifts in the nature of young adulthood to prepare for midlife parents’ future aging. PMID:29795793

  5. Wound-Related Allergic/Irritant Contact Dermatitis.

    PubMed

    Alavi, Afsaneh; Sibbald, R Gary; Ladizinski, Barry; Saraiya, Ami; Lee, Kachiu C; Skotnicki-Grant, Sandy; Maibach, Howard

    2016-06-01

    To provide information from a literature review about the prevention, recognition, and treatment for contact dermatitis. This continuing education activity is intended for physicians and nurses with an interest in skin and wound care. After participating in this educational activity, the participant should be better able to:1. Identify signs and symptoms of and diagnostic measures for contact dermatitis.2. Identify causes and risks for contact dermatitis.3. Select appropriate treatment for contact dermatitis and its prevention. Contact dermatitis to wound care products is a common, often neglected problem. A review was conducted to identify articles relevant to contact dermatitis.A PubMed English-language literature review was conducted for appropriate articles published between January 2000 and December 2015.Contact dermatitis is both irritant (80% of cases) or allergic (20% of cases). Frequent use of potential contact allergens and impaired barrier function of the skin can lead to rising sensitization in patients with chronic wounds. Common known allergens to avoid in wound care patients include fragrances, colophony, lanolin, and topical antibiotics.Clinicians should be cognizant of the allergens in wound care products and the potential for sensitization. All medical devices, including wound dressings, adhesives, and bandages, should be labeled with their complete ingredients, and manufacturers should be encouraged to remove common allergens from wound care products, including topical creams, ointments, and dressings.

  6. Evaluation of touch-sensitive screen tablet terminal button size and spacing accounting for effect of fingertip contact angle.

    PubMed

    Nishimura, T; Doi, K; Fujimoto, H

    2015-08-01

    Touch-sensitive screen terminals enabling intuitive operation are used as input interfaces in a wide range of fields. Tablet terminals are one of the most common devices with a touch-sensitive screen. They have a feature of good portability, enabling use under various conditions. On the other hand, they require a GUI designed to prevent decrease of usability under various conditions. For example, the angle of fingertip contact with the display changes according to finger posture during operation and how the case is held. When a human fingertip makes contact with an object, the contact area between the fingertip and contact object increases or decreases as the contact angle changes. A touch-sensitive screen detects positions using the change in capacitance of the area touched by the fingertip; hence, differences in contact area between the touch-sensitive screen and fingertip resulting from different forefinger angles during operation could possibly affect operability. However, this effect has never been studied. We therefore conducted an experiment to investigate the relationship between size/spacing and operability, while taking the effect of fingertip contact angle into account. As a result, we have been able to specify the button size and spacing conditions that enable accurate and fast operation regardless of the forefinger contact angle.

  7. Contact Dermatitis for the Practicing Allergist.

    PubMed

    Bernstein, David I

    2015-01-01

    This article provides an overview of important practice recommendations from the recently updated Contact Dermatitis Practice Parameter. This updated parameter provides essential recommendations pertaining to clinical history, physical examination, and patch testing evaluation of patients suspected of allergic contact dermatitis. In addition to providing guidance for performing and interpreting closed patch testing, the updated parameter provides concrete recommendations for assessing metal hypersensitivity in patients receiving prosthetic devices, for evaluating workers with occupational contact dermatitis, and also for addressing allergic contact dermatitis in children. Finally, the document provides practical recommendations useful for educating patients regarding avoidance of exposure to known contact sensitizers in the home and at work. The Contact Dermatitis Parameter is designed as a practical, evidence-based clinical tool to be used by allergists and dermatologists who routinely are called upon to evaluate patients with skin disorders. Copyright © 2015 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

  8. Crashworthiness simulations with DYNA3D

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schauer, D.A.; Hoover, C.G.; Kay, G.J.

    1996-04-01

    Current progress in parallel algorithm research and applications in vehicle crash simulation is described for the explicit, finite element algorithms in DYNA3D. Problem partitioning methods and parallel algorithms for contact at material interfaces are the two challenging algorithm research problems that are addressed. Two prototype parallel contact algorithms have been developed for treating the cases of local and arbitrary contact. Demonstration problems for local contact are crashworthiness simulations with 222 locally defined contact surfaces and a vehicle/barrier collision modeled with arbitrary contact. A simulation of crash tests conducted for a vehicle impacting a U-channel small sign post embedded in soilmore » has been run on both the serial and parallel versions of DYNA3D. A significant reduction in computational time has been observed when running these problems on the parallel version. However, to achieve maximum efficiency, complex problems must be appropriately partitioned, especially when contact dominates the computation.« less

  9. High-resolution of particle contacts via fluorophore exclusion in deep-imaging of jammed colloidal packings

    NASA Astrophysics Data System (ADS)

    Kyeyune-Nyombi, Eru; Morone, Flaviano; Liu, Wenwei; Li, Shuiqing; Gilchrist, M. Lane; Makse, Hernán A.

    2018-01-01

    Understanding the structural properties of random packings of jammed colloids requires an unprecedented high-resolution determination of the contact network providing mechanical stability to the packing. Here, we address the determination of the contact network by a novel strategy based on fluorophore signal exclusion of quantum dot nanoparticles from the contact points. We use fluorescence labeling schemes on particles inspired by biology and biointerface science in conjunction with fluorophore exclusion at the contact region. The method provides high-resolution contact network data that allows us to measure structural properties of the colloidal packing near marginal stability. We determine scaling laws of force distributions, soft modes, correlation functions, coordination number and free volume that define the universality class of jammed colloidal packings and can be compared with theoretical predictions. The contact detection method opens up further experimental testing at the interface of jamming and glass physics.

  10. 75 FR 62363 - Notice of Request for Extension of Approval of an Information Collection; Bees and Related Articles

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-08

    ...] Notice of Request for Extension of Approval of an Information Collection; Bees and Related Articles... articles. DATES: We will consider all comments that we receive on or before December 7, 2010. ADDRESSES... INFORMATION CONTACT: For information on regulations for the importation of bees and related articles, contact...

  11. 43 CFR Appendix B to Part 2 - Internet Addresses

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Page: http://www.doi.gov 2. DOI FOIA Home Page: http://www.doi.gov/foia/ 3. DOI Reference Guide for Obtaining Information: http://www.doi.gov/foia/foitabl.htm 4. List of DOI Public Affairs Offices: http://www.doi.gov/foia/list.html 5. DOI FOIA Contacts: http://www.doi.gov/foia/contacts.html 6. DOI FOIA...

  12. 43 CFR Appendix B to Part 2 - Internet Addresses

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Page: http://www.doi.gov 2. DOI FOIA Home Page: http://www.doi.gov/foia/ 3. DOI Reference Guide for Obtaining Information: http://www.doi.gov/foia/foitabl.htm 4. List of DOI Public Affairs Offices: http://www.doi.gov/foia/list.html 5. DOI FOIA Contacts: http://www.doi.gov/foia/contacts.html 6. DOI FOIA...

  13. 75 FR 425 - Extension of Approved Information Collection, OMB Control Number 1004-0073

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-05

    ... be available for public review at the L Street address during regular business hours (7:45 a.m. to 4:15 p.m.), Monday through Friday, excluding Federal holidays. FOR FURTHER INFORMATION CONTACT: You may contact John A. Lewis, Division of Solid Minerals at (202) 912-7116 (Commercial or FTS). Persons who use a...

  14. 77 FR 51606 - Notice of Request for Expressions of Interest by Environmental Experts in Assisting the CAFTA-DR...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-24

    .... Full Name. 2. Contact information (should include a business address, telephone number, and email... individuals, in addition to the author of the letter of reference, who are willing to serve as a reference and provide information regarding the expert's professional experience (should include the names, contact...

  15. Verification Challenges of Dynamic Testing of Space Flight Hardware

    NASA Technical Reports Server (NTRS)

    Winnitoy, Susan

    2010-01-01

    The Six Degree-of-Freedom Dynamic Test System (SDTS) is a test facility at the National Aeronautics and Space Administration (NASA) Johnson Space Center in Houston, Texas for performing dynamic verification of space structures and hardware. Some examples of past and current tests include the verification of on-orbit robotic inspection systems, space vehicle assembly procedures and docking/berthing systems. The facility is able to integrate a dynamic simulation of on-orbit spacecraft mating or demating using flight-like mechanical interface hardware. A force moment sensor is utilized for input to the simulation during the contact phase, thus simulating the contact dynamics. While the verification of flight hardware presents many unique challenges, one particular area of interest is with respect to the use of external measurement systems to ensure accurate feedback of dynamic contact. There are many commercial off-the-shelf (COTS) measurement systems available on the market, and the test facility measurement systems have evolved over time to include two separate COTS systems. The first system incorporates infra-red sensing cameras, while the second system employs a laser interferometer to determine position and orientation data. The specific technical challenges with the measurement systems in a large dynamic environment include changing thermal and humidity levels, operational area and measurement volume, dynamic tracking, and data synchronization. The facility is located in an expansive high-bay area that is occasionally exposed to outside temperature when large retractable doors at each end of the building are opened. The laser interferometer system, in particular, is vulnerable to the environmental changes in the building. The operational area of the test facility itself is sizeable, ranging from seven meters wide and five meters deep to as much as seven meters high. Both facility measurement systems have desirable measurement volumes and the accuracies vary within the respective volumes. In addition, because this is a dynamic facility with a moving test bed, direct line-of-sight may not be available at all times between the measurement sensors and the tracking targets. Finally, the feedback data from the active test bed along with the two external measurement systems must be synchronized to allow for data correlation. To ensure the desired accuracy and resolution of these systems, calibration of the systems must be performed regularly. New innovations in sensor technology itself are periodically incorporated into the facility s overall measurement scheme. In addressing the challenges of the measurement systems, the facility is able to provide essential position and orientation data to verify the dynamic performance of space flight hardware.

  16. 18 CFR 157.6 - Applications; general requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... provide the title of the pamphlet and indicate its availability at the Commission's Internet address; (iii... applicant, including a local or toll-free phone number and a name of a specific person to contact who is... the Commission's Internet address and the telephone number for the Commission's Office of External...

  17. 18 CFR 157.6 - Applications; general requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... provide the title of the pamphlet and indicate its availability at the Commission's Internet address; (iii... applicant, including a local or toll-free phone number and a name of a specific person to contact who is... the Commission's Internet address and the telephone number for the Commission's Office of External...

  18. 18 CFR 157.6 - Applications; general requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... provide the title of the pamphlet and indicate its availability at the Commission's Internet address; (iii... applicant, including a local or toll-free phone number and a name of a specific person to contact who is... the Commission's Internet address and the telephone number for the Commission's Office of External...

  19. 18 CFR 157.6 - Applications; general requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... provide the title of the pamphlet and indicate its availability at the Commission's Internet address; (iii... applicant, including a local or toll-free phone number and a name of a specific person to contact who is... the Commission's Internet address and the telephone number for the Commission's Office of External...

  20. 78 FR 34654 - New England Fishery Management Council (NEFMC); Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-10

    .... ADDRESSES: Meeting Address: The meeting will be held at the Holiday Inn, One Newbury Street, Peabody, MA... Council, 50 Water Street, Mill 2, Newburyport, MA 01950. FOR FURTHER INFORMATION CONTACT: Thomas A. Nies.... Dated: June 4, 2013. Tracey L. Thompson, Acting Deputy Director, Office of Sustainable Fisheries...

  1. 77 FR 38850 - Federal Property Suitable as Facilities to Assist the Homeless

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-29

    ... address), providers should contact the appropriate landholding agencies at the following addresses: AIR FORCE: Mr. Robert Moore, Air Force Real Property Agency, 143 Billy Mitchell Blvd., San Antonio, TX 78226... needed; potential ground water contamination; secured area; need approval to access and remove property...

  2. 76 FR 54781 - Federal Property Suitable as Facilities To Assist the Homeless

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-02

    ... address), providers should contact the appropriate landholding agencies at the following addresses: Air Force: Mr. Robert Moore, Air Force Real Property Agency, 143 Billy Mitchell Blvd., San Antonio, TX 78226... A101, McDill Rd., Bedford MA 07131, Landholding Agency: Air Force, Property Number: 18201130003, Status...

  3. 77 FR 28638 - Sunshine Act Meeting Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-15

    ... Meeting), (Contact: Rani Franovich, 301-415-1868). This meeting will be webcast live at the Web address...). This meeting will be webcast live at the Web address--www.nrc.gov. Week of June 11, 2012--Tentative... Nuclear Regulatory Commission (NRC) on Grid Reliability (Public Meeting) To be held at FERC Headquarters...

  4. 75 FR 9451 - Sunshine Act Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-02

    ..., 301-415-6749.) This meeting will be webcast live at the Web address-- http://www.nrc.gov , Week of... Commission and the Nuclear Regulatory Commission on Grid Reliability (Public Meeting). (Contact: Kenn Miller, 301-415-3152.) This meeting will be webcast live at the Web address-- http://www.nrc.gov . Week of...

  5. 77 FR 48491 - Regulatory New Drug Review: Solutions for Study Data Exchange Standards; Notice of Meeting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-14

    ... INFORMATION CONTACT: Ron Fitzmartin, Office of Planning & Informatics, Center for Drug Evaluation and Research... limited. Send registration information (including name, title, firm name, country of citizenship, address, telephone and fax number, and email address) to Fatima Elnigoumi, Center for Drug Evaluation and Research...

  6. 75 FR 55540 - New England Fishery Management Council; Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-13

    ... Council, 50 Water Street, Mill 2, Newburyport, MA 01950. FOR FURTHER INFORMATION CONTACT: Paul J. Howard..., measures to maximize sampling, measures to address net slippage, maximized retention, electronic monitoring... Scallop FMP. If approved these would: (1) include annual catch limits; (2) address excess capacity in the...

  7. 78 FR 18931 - Proposed Establishment of Class E Airspace; Bass Harbor, ME

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-28

    ... through the Internet at http://www.regulations.gov . FOR FURTHER INFORMATION CONTACT: John Fornito... the proposal. Communications should identify both docket numbers (FAA Docket No. FAA-2012-0793... ADDRESSES section for address and phone number). You may also submit comments through the Internet at http...

  8. 78 FR 6260 - Proposed Amendment of Class E Airspace; Kingston, NY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-30

    ... received comments through the Internet at http://www.regulations.gov . FOR FURTHER INFORMATION CONTACT... aspects of the proposal. Communications should identify both docket numbers (FAA Docket No. FAA-2011-0831... ADDRESSES section for address and phone number). You may also submit comments through the Internet at http...

  9. 78 FR 54412 - Proposed Establishment of Class E Airspace; Chatom, AL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-04

    ... through the Internet at http://www.regulations.gov . FOR FURTHER INFORMATION CONTACT: John Fornito... the proposal. Communications should identify both docket numbers (FAA Docket No. FAA-2012-1186... ADDRESSES section for address and phone number). You may also submit comments through the Internet at http...

  10. 75 FR 64970 - Proposed Amendment of Class E Airspace; Henderson, KY

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-21

    ... through the Internet at http://www.regulations.gov . FOR FURTHER INFORMATION CONTACT: Melinda Giddens... the proposal. Communications should identify both docket numbers (FAA Docket No. FAA-2010-0937... ADDRESSES section for address and phone number). You may also submit comments through the Internet at http...

  11. 78 FR 18929 - Proposed Establishment of Class E Airspace; Boothbay, ME

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-28

    ... received comments through the Internet at http://www.regulations.gov . FOR FURTHER INFORMATION CONTACT... aspects of the proposal. Communications should identify both docket numbers (FAA Docket No. FAA-2012-0792... ADDRESSES section for address and phone number). You may also submit comments through the Internet at http...

  12. 75 FR 42631 - Proposed Establishment of Class E Airspace; Wolfeboro, NH

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-22

    ... received comments through the Internet at http://www.regulations.gov . FOR FURTHER INFORMATION CONTACT... aspects of the proposal. Communications should identify both docket numbers (FAA Docket No. FAA-2010-0321... ADDRESSES section for address and phone number). You may also submit comments through the Internet at http...

  13. 76 FR 64295 - Proposed Amendment of Class E Airspace; Huntington, WV

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-18

    ... through the Internet at http://www.regulations.gov . FOR FURTHER INFORMATION CONTACT: John Fornito... the proposal. Communications should identify both docket numbers (FAA Docket No. FAA-2011-1057... ADDRESSES section for address and phone number). You may also submit comments through the Internet at http...

  14. 50 CFR 600.1410 - Registry process.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ....nmfs.noaa.gov or by calling a toll-free telephone number available by contacting NMFS or at the NMFS website. (b) Individuals must submit their name; address; telephone number; date of birth; region(s) of... vessel owner or operator must submit vessel owner name, address, date of birth, and telephone number...

  15. 78 FR 44600 - Comment Request for Information Collection for Veterans Retraining Assistance Program Participant...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-24

    ...: Written comments must be submitted to the office listed in the addresses section below on or before September 23, 2013. ADDRESSES: Submit written comments to Andrew Ridgeway, Office of Workforce Investment... contacting the office listed above. SUPPLEMENTARY INFORMATION: I. Background ETA seeks extension without...

  16. 19 CFR 207.11 - Contents of petition.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., phone number, and contact person(s) for each producer; (iii) A listing of all U.S. importers of the subject merchandise, including street addresses and phone numbers for each importer; (iv) Identification... set forth the name, address, and telephone number of the petitioner and any such officer, attorney, or...

  17. 19 CFR 207.11 - Contents of petition.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., phone number, and contact person(s) for each producer; (iii) A listing of all U.S. importers of the subject merchandise, including street addresses and phone numbers for each importer; (iv) Identification... set forth the name, address, and telephone number of the petitioner and any such officer, attorney, or...

  18. 19 CFR 207.11 - Contents of petition.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., phone number, and contact person(s) for each producer; (iii) A listing of all U.S. importers of the subject merchandise, including street addresses and phone numbers for each importer; (iv) Identification... set forth the name, address, and telephone number of the petitioner and any such officer, attorney, or...

  19. 19 CFR 207.11 - Contents of petition.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., phone number, and contact person(s) for each producer; (iii) A listing of all U.S. importers of the subject merchandise, including street addresses and phone numbers for each importer; (iv) Identification... set forth the name, address, and telephone number of the petitioner and any such officer, attorney, or...

  20. 34 CFR 682.207 - Due diligence in disbursing a loan.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... accessing the Department's Postsecondary Education Participants System (PEPS) Database (or any successor... status for which the loan was certified. (3) For a continuing student, contacting the foreign school the... address of the lender, servicer, or guaranty agency to which any inquiries should be addressed. (3) Except...

  1. 34 CFR 682.207 - Due diligence in disbursing a loan.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... accessing the Department's Postsecondary Education Participants System (PEPS) Database (or any successor... status for which the loan was certified. (3) For a continuing student, contacting the foreign school the... address of the lender, servicer, or guaranty agency to which any inquiries should be addressed. (3) Except...

  2. 34 CFR 682.207 - Due diligence in disbursing a loan.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... accessing the Department's Postsecondary Education Participants System (PEPS) Database (or any successor... status for which the loan was certified. (3) For a continuing student, contacting the foreign school the... address of the lender, servicer, or guaranty agency to which any inquiries should be addressed. (3) Except...

  3. 50 CFR 600.1410 - Registry process.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ....nmfs.noaa.gov or by calling a toll-free telephone number available by contacting NMFS or at the NMFS website. (b) Individuals must submit their name; address; telephone number; date of birth; region(s) of... vessel owner or operator must submit vessel owner name, address, date of birth, and telephone number...

  4. 48 CFR 722.805-70 - Procedures.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... then consult the OFCCP's National Preaward Registry at the internet website in 48 CFR 22.805(a)(4) (i... requested by the OFCCP regional office: (i) Name, title, address, and telephone number of a contract person..., address, and telephone number of the person contacted, a summary of the information presented, and any...

  5. 48 CFR 722.805-70 - Procedures.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... then consult the OFCCP's National Preaward Registry at the internet website in 48 CFR 22.805(a)(4) (i... requested by the OFCCP regional office: (i) Name, title, address, and telephone number of a contract person..., address, and telephone number of the person contacted, a summary of the information presented, and any...

  6. 48 CFR 722.805-70 - Procedures.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... then consult the OFCCP's National Preaward Registry at the internet website in 48 CFR 22.805(a)(4) (i... requested by the OFCCP regional office: (i) Name, title, address, and telephone number of a contract person..., address, and telephone number of the person contacted, a summary of the information presented, and any...

  7. 50 CFR 600.1410 - Registry process.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ....nmfs.noaa.gov or by calling a toll-free telephone number available by contacting NMFS or at the NMFS website. (b) Individuals must submit their name; address; telephone number; date of birth; region(s) of... vessel owner or operator must submit vessel owner name, address, date of birth, and telephone number...

  8. 48 CFR 722.805-70 - Procedures.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... then consult the OFCCP's National Preaward Registry at the internet website in 48 CFR 22.805(a)(4) (i... requested by the OFCCP regional office: (i) Name, title, address, and telephone number of a contract person..., address, and telephone number of the person contacted, a summary of the information presented, and any...

  9. 50 CFR 600.1410 - Registry process.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ....nmfs.noaa.gov or by calling a toll-free telephone number available by contacting NMFS or at the NMFS website. (b) Individuals must submit their name; address; telephone number; date of birth; region(s) of... vessel owner or operator must submit vessel owner name, address, date of birth, and telephone number...

  10. 50 CFR 600.1410 - Registry process.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ....nmfs.noaa.gov or by calling a toll-free telephone number available by contacting NMFS or at the NMFS website. (b) Individuals must submit their name; address; telephone number; date of birth; region(s) of... vessel owner or operator must submit vessel owner name, address, date of birth, and telephone number...

  11. 48 CFR 722.805-70 - Procedures.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... then consult the OFCCP's National Preaward Registry at the internet website in 48 CFR 22.805(a)(4) (i... requested by the OFCCP regional office: (i) Name, title, address, and telephone number of a contract person..., address, and telephone number of the person contacted, a summary of the information presented, and any...

  12. 77 FR 5840 - Notice of Inventory Completion: Kingman Museum, Incorporated, Battle Creek, MI; Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-06

    ... DEPARTMENT OF THE INTERIOR National Park Service Notice of Inventory Completion: Kingman Museum... contact the Kingman Museum, Incorporated at the address below by March 7, 2012. ADDRESSES: Beth Yahne, Kingman Museum, Inc., 175 Limit Street, Battle Creek, MI 49037, telephone (269) 965-5117. SUPPLEMENTARY...

  13. Contact Us | Buildings | NREL

    Science.gov Websites

    provide your name, email address, and message below. When you are finished, click "Send Message." ; NOTE: If you enter your email address incorrectly, we will be unable to reply. If you see this don't fill out this input box. Your Name * Your Email * Your Message * Submit

  14. 75 FR 53333 - Notice of Filing of Plats of Survey, Alaska

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-31

    ... CONTACT: Stephen B. Hamrick, 907-271-5481, fax 907-271-4549, e-mail [email protected] . SUPPLEMENTARY... guarantee that we will be able to do so. Authority: 43 U.S.C. 3; 53. Stephen B. Hamrick, Chief Cadastral...

  15. A fast pH-switchable and self-healing supramolecular hydrogel carrier for guided, local catheter injection in the infarcted myocardium.

    PubMed

    Bastings, Maartje M C; Koudstaal, Stefan; Kieltyka, Roxanne E; Nakano, Yoko; Pape, A C H; Feyen, Dries A M; van Slochteren, Frebus J; Doevendans, Pieter A; Sluijter, Joost P G; Meijer, E W; Chamuleau, Steven A J; Dankers, Patricia Y W

    2014-01-01

    Minimally invasive intervention strategies after myocardial infarction use state-of-the-art catheter systems that are able to combine mapping of the infarcted area with precise, local injection of drugs. To this end, catheter delivery of drugs that are not immediately pumped out of the heart is still challenging, and requires a carrier matrix that in the solution state can be injected through a long catheter, and instantaneously gelates at the site of injection. To address this unmet need, a pH-switchable supramolecular hydrogel is developed. The supramolecular hydrogel is switched into a liquid at pH > 8.5, with a viscosity low enough to enable passage through a 1-m long catheter while rapidly forming a hydrogel in contact with tissue. The hydrogel has self-healing properties taking care of adjustment to the injection site. Growth factors are delivered from the hydrogel thereby clearly showing a reduction of infarct scar in a pig myocardial infarction model. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. Framework for near-field-communication-based geo-localization and personalization for Android-based smartphones--application in hospital environments.

    PubMed

    Meng, Philipp; Fehre, Karsten; Rappelsberger, Andrea; Adlassnig, Klaus-Peter

    2014-01-01

    Various applications using near field communication (NFC) have been developed for the medical sector. As a method of short-range wireless contact-driven data transfer, NFC is a useful tool in medicine. It can be used to transfer data such as blood pressure, control adherence to medication, or transmit in vivo data. The first proposed general framework uses NFC as a mechanism for indoor geo-localization in hospitals. NFC geo-localization is economical compared to classical concepts using indoor GPS or WLAN triangulation, and the granularity of location retrieval can be defined at a tag level. Using this framework, we facilitate the development of medical applications that require exact indoor geo-localization. Multi-user Android systems are addressed in the second framework. Using private NFC tags, users are able to carry on their personal settings for enabled applications. This eliminates the need for multiple user accounts on common Android devices, improves usability, and eases technical administration. Based on the prototypes presented here, we show a novel concept of using NFC-enabled Android devices in hospital environments.

  17. Thermal Characterization for a Modular 3-D Multichip Module

    NASA Technical Reports Server (NTRS)

    Fan, Mark S.; Plante, Jeannette; Shaw, Harry

    2000-01-01

    NASA Goddard Space Flight Center has designed a high-density modular 3-D multichip module (MCM) for future spaceflight use. This MCM features a complete modular structure, i.e., each stack can be removed from the package without damaging the structure. The interconnection to the PCB is through the Column Grid Array (CGA) technology. Because of its high-density nature, large power dissipation from multiple layers of circuitry is anticipated and CVD diamond films are used in the assembly for heat conduction enhancement. Since each stacked layer dissipates certain amount of heat, designing effective heat conduction paths through each stack and balancing the heat dissipation within each stack for optimal thermal performance become a challenging task. To effectively remove the dissipated heat from the package, extensive thermal analysis has been performed with finite element methods. Through these analyses, we are able to improve the thermal design and increase the total wattage of the package for maximum electrical performance. This paper provides details on the design-oriented thermal analysis and performance enhancement. It also addresses issues relating to contact thermal resistance between the diamond film and the metallic heat conduction paths.

  18. [Allergy to cosmetics. I. Fragrances].

    PubMed

    Kieć-Swierczyńska, Marta; Krecisz, Beata; Swierczyńska-Machura, Dominika

    2004-01-01

    The authors report current information on allergy to aromatic agents present in cosmetics and products of household chemistry. In the perfume industry, about 3000 aromas are used. Single products may contain from 10 to 300 compounds. The problem of difficulties encountered in the diagnosis of hypersensitivity to odors is addressed. The mixture of 8 such products used in diagnostic screening is able to detect allergy only in about 30% of patients who do not tolerate cosmetics. Changing frequency of allergy to individual aromas is discussed. It has been now observed that cinnamon products are less allergic than chemical compounds present in oak moss. Since the 1990s of the last century, allergy to a synthetic aromatic agent, Lyral is the subject of interest in many research centers involved in studies of contact allergy. Half the cosmetics present in European markets, especially deodorants, after shave cosmetics, hand and body lotions contain this agent. It induces positive reactions in about 10% of patients allergic to aromatic agents. Detection of allergy to Lyral is difficult as it is not included in the set of commercial allergens used to diagnose hypersensitivity to aromatic agents.

  19. Magnetowetting and sliding motion of a sessile ferrofluid droplet in the presence of a permanent magnet.

    PubMed

    Nguyen, Nam-Trung; Zhu, Guiping; Chua, Yong-Chin; Phan, Vinh-Nguyen; Tan, Say-Hwa

    2010-08-03

    Motion of a droplet on a planar surface has applications in droplet-based lab on a chip technology. This paper reports the experimental results of the shape, contact angles, and motion of ferrofluid droplets driven by a permanent magnet on a planar homogeneous surface. The water-based ferrofluid in use is a colloidal suspension of single-domain magnetic nanoparticles. The effect of the magnetic field on the apparent contact angle of the ferrofluid droplet was first investigated. The results show that an increasing magnetic flux decreases the apparent contact angle of a sessile ferrofluid droplet. Next, the dynamic contact angle was investigated by observing the shape and the motion of a sessile ferrofluid droplet. The advancing and receding contact angles of the moving ferrofluid were measured at different moving speeds and magnetic field strengths. The measured contact angles were used to estimate the magnitude of the forces involved in the sliding motion. Scaling analysis was carried out to derive the critical velocity, beyond which the droplet is not able to catch up with the moving magnet.

  20. Non-Dissipative Structural Evolutions in Granular Materials

    NASA Astrophysics Data System (ADS)

    Pouragha, Mehdi; Wan, Richard

    2017-06-01

    The structure of the contact network in granular assemblies can evolve due to either dissipative mechanisms such as sliding at contact points, or non-dissipative mechanisms through the phenomenon of contact gain and loss. Being associated with negligible deformations, non-dissipative mechanisms is actually active even in the small strain range of 10-3, especially in the case of densely packed assemblies. Hence, from a constitutive modelling point of view, it is crucial to be able to estimate such non-dissipative evolutions since both elastic and plastic properties of granular assemblies highly depend on contact network characteristics. The current study proposes an analytical scheme that allows us to estimate the non-dissipative contact gain/loss regime in terms of directional changes in the average contact force. The probability distribution of contact forces is used to compute the number of lost contact for each direction. Similarly, the number of newly formed contacts is estimated by considering the probability distribution of the gap between neighbouring particles. Based on the directional contact gain/loss computed, the changes in coordination number and fabric anisotropy can be found which, together with statistical treatments of Love-Weber stress expression, form a complete system of equations describing the evolution of other controlling microvariables. Finally, the results of the calculations have been compared with DEM simulations which verify the accuracy of the proposed scheme.

  1. Shear test on viscoelastic granular material using Contact Dynamics simulations

    NASA Astrophysics Data System (ADS)

    Quezada, Juan Carlos; Sagnol, Loba; Chazallon, Cyrille

    2017-06-01

    By means of 3D contact dynamic simulations, the behavior of a viscoelastic granular material under shear loading is investigated. A viscoelastic fluid phase surrounding the solid particles is simulated by a contact model acting between them. This contact law was implemented in the LMGC90 software, based on the Burgers model. This model is able to simulate also the effect of creep relaxation. To validate the proposed contact model, several direct shear tests were performed, experimentally and numerically using the Leutner device. The numerical samples were created using spheres with two particle size distribution, each one identified for two layers from a road structure. Our results show a reasonable agreement between experimental and numerical data regarding the strain-stress evolution curves and the stress levels measured at failure. The proposed model can be used to simulate the mechanical behavior of multi-layer road structure and to study the influence of traffic on road deformation, cracking and particles pull-out induced by traffic loading.

  2. Applicability of contact angle techniques used in the analysis of contact lenses, part 1: comparative methodologies.

    PubMed

    Campbell, Darren; Carnell, Sarah Maria; Eden, Russell John

    2013-05-01

    Contact angle, as a representative measure of surface wettability, is often employed to interpret contact lens surface properties. The literature is often contradictory and can lead to confusion. This literature review is part of a series regarding the analysis of hydrogel contact lenses using contact angle techniques. Here we present an overview of contact angle terminology, methodology, and analysis. Having discussed this background material, subsequent parts of the series will discuss the analysis of contact lens contact angles and evaluate differences in published laboratory results. The concepts of contact angle, wettability and wetting are presented as an introduction. Contact angle hysteresis is outlined and highlights the advantages in using dynamic analytical techniques over static methods. The surface free energy of a material illustrates how contact angle analysis is capable of providing supplementary surface characterization. Although single values are able to distinguish individual material differences, surface free energy and dynamic methods provide an improved understanding of material behavior. The frequently used sessile drop, captive bubble, and Wilhelmy plate techniques are discussed. Their use as both dynamic and static methods, along with the advantages and disadvantages of each technique, is explained. No single contact angle technique fully characterizes the wettability of a material surface, and the application of complimenting methods allows increased characterization. At present, there is not an ISO standard method designed for soft materials. It is important that each contact angle technique has a standard protocol, as small protocol differences between laboratories often contribute to a variety of published data that are not easily comparable.

  3. Test Report: Low-Cost Access to TDRS Using TOPEX to Emulate Small Satellite Performance

    NASA Technical Reports Server (NTRS)

    Horan, Stephen

    1997-01-01

    This report lists the objectives and conclusions of a series of experimental contacts between the TOPEX and the TDRS satellites. These experiments are designed to verify the theoretical prediction that a spin-stabilized satellite with a broad-beam, zenith-pointing antenna can have regular, significant contacts with the TDRS and use those contacts for data services. This series of experiments is a joint project between the experimenters at New Mexico State University (NMSU), the National Aeronautics and Space Administration (NASA) Goddard Space Flight Center (GSFC), and the Jet Propulsion Laboratory (JPL). In these experiments, we show that: (1) The satellite contacts during the experiment begin and end as predicted prior to the experiment; (2) The data contact is held for the desired contact duration; (3) The data quality through the contact is high and similar to that required by actual project needs; and (4) The receiving hardware at the White Sands Complex (WSC) is able to track the signals better than expected by analysis of the antenna pattern effects alone predict. We believe that these experiments successfully demonstrate the basic concept and its validity with actual spacecraft systems.

  4. Reducing perceived barriers to nursing homes data entry in the advancing excellence campaign: the role of LANEs (Local Area Networks for Excellence).

    PubMed

    Bakerjian, Debra; Bonner, Alice; Benner, Carol; Caswell, Cheryl; Weintraub, Alissa; Koren, Mary Jane

    2011-09-01

    Advancing Excellence (AE) is a coalition-based campaign concerned with how society cares for its elderly and disabled citizens. The purpose of this project was to work with a small group of volunteer nursing homes and with local quality improvement networks called LANEs (Local Area Networks for Excellence) in 6 states in a learning collaborative. The purpose of the collaborative was to determine effective ways for LANEs to address and mitigate perceived barriers to nursing home data entry in the national Advancing Excellence campaign and to test methods by which local quality improvement networks could support nursing homes as they enter data on the AE Web site. A semistructured telephone survey of nursing homes was conducted in 6 states. Participants included LANEs from California, Georgia, Massachusetts, Michigan, Oklahoma, and Washington. Facility characteristics were obtained from a series of questions during the telephone interview. Three states (GA, MA, OK) piloted a new spreadsheet and process for entering data on staff turnover, and 3 states (CA, MI, WA) piloted a new spreadsheet and process for entering data on consistent assignment. Many of the nursing homes we contacted had not entered data for organizational goals on the national Web site, but all were able to do so with telephone assistance from the LANE. Eighty-five percent of nursing homes said they would be able to collect information on advance directives if tools (eg, spreadsheets) were provided. Over 40% of nursing homes, including for-profit homes, were willing to have staff and residents/families enter satisfaction data directly on an independent Web site. Nursing homes were able to convey concerns and questions about the process of goal entry, and offer suggestions to the LANEs during semistructured telephone interviews. The 6 LANEs discussed nursing home responses on their regularly scheduled calls, and useful strategies were shared across states. Nursing homes reported that they are using Advancing Excellence target setting and goal entry to improve care, and that they would use new tools such as those for measuring satisfaction, consistent assignment, and advance directives. Having LANE members contact nursing homes directly by telephone engaged the nursing homes in providing valuable feedback on new Advancing Excellence goals and data entry. It also provided an opportunity to clarify issues related to the campaign and ongoing quality improvement efforts, including culture change. Published by Elsevier Inc.

  5. Intergroup contact throughout the lifespan modulates implicit racial biases across perceivers' racial group.

    PubMed

    Kubota, Jennifer T; Peiso, Jaelyn; Marcum, Kori; Cloutier, Jasmin

    2017-01-01

    Few researchers have investigated how contact across the lifespan influences racial bias and whether diversity of contact is beneficial regardless of the race of the perceiver. This research aims to address these gaps in the literature with a focus on how diversity in childhood and current contact shapes implicit racial bias across perceivers' racial group. In two investigations, participants completed an Implicit Association Test and a self-report measure of the racial diversity of their current and childhood contact. In both studies, increased contact with Black compared with White individuals, both in childhood (Study 2) and currently (Studies 1 and 2), was associated with reduced implicit pro-White racial bias. For Black individuals (Study 2) more contact with Black compared with White individuals also was associated with reduced implicit pro-White racial bias. These findings suggest that diversity in contact across the lifespan may be related to reductions in implicit racial biases and that this relationship may generalize across racial groups.

  6. Intergroup contact throughout the lifespan modulates implicit racial biases across perceivers’ racial group

    PubMed Central

    Peiso, Jaelyn; Marcum, Kori; Cloutier, Jasmin

    2017-01-01

    Few researchers have investigated how contact across the lifespan influences racial bias and whether diversity of contact is beneficial regardless of the race of the perceiver. This research aims to address these gaps in the literature with a focus on how diversity in childhood and current contact shapes implicit racial bias across perceivers’ racial group. In two investigations, participants completed an Implicit Association Test and a self-report measure of the racial diversity of their current and childhood contact. In both studies, increased contact with Black compared with White individuals, both in childhood (Study 2) and currently (Studies 1 and 2), was associated with reduced implicit pro-White racial bias. For Black individuals (Study 2) more contact with Black compared with White individuals also was associated with reduced implicit pro-White racial bias. These findings suggest that diversity in contact across the lifespan may be related to reductions in implicit racial biases and that this relationship may generalize across racial groups. PMID:28700624

  7. Understanding the Taliban and Insurgency in Afghanistan

    DTIC Science & Technology

    2007-01-01

    simple, for that organization has been able to build on tribal kinship networks and a charis- matic mullah phenomenon to mobilize a critical and dynamic...PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval Postgraduate School,Department of National Security Affairs,Monterey,CA,93943 8. PERFORMING... ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR/MONITOR’S REPORT NUMBER(S

  8. Theory of point contact spectroscopy in correlated materials

    DOE PAGES

    Lee, Wei-Cheng; Park, Wan Kyu; Arham, Hamood Z.; ...

    2015-01-05

    Here, we developed a microscopic theory for the point-contact conductance between a metallic electrode and a strongly correlated material using the nonequilibrium Schwinger-Kadanoff-Baym-Keldysh formalism. We explicitly show that, in the classical limit, contact size shorter than the scattering length of the system, the microscopic model can be reduced to an effective model with transfer matrix elements that conserve in-plane momentum. We found that the conductance dI/dV is proportional to the effective density of states, that is, the integrated single-particle spectral function A(ω = eV) over the whole Brillouin zone. From this conclusion, we are able to establish the conditions undermore » which a non-Fermi liquid metal exhibits a zero-bias peak in the conductance. Lastly, this finding is discussed in the context of recent point-contact spectroscopy on the iron pnictides and chalcogenides, which has exhibited a zero-bias conductance peak.« less

  9. Relationship between the public's belief in recovery, level of mental illness stigma, and previous contact.

    PubMed

    Barczyk, Amanda N

    2015-01-01

    Disbelief exits that individuals who have a mental health condition are able to recover and fully function in life. This study analyzed 1,437 adults from the 2006 General Social Survey. Structural equation modeling (1) examined the relationship between respondents' level of prejudicial attitudes and social distance (i.e., stigma) toward individuals who have a mental health condition and their belief in the potential of recovery (2) tested whether previous contact with an individual who received treatment was a mediator. Findings indicated that the belief in recovery led to lower levels of social distance. Prejudicial attitudes were found to be a predictor of one's level of social distance. Previous contact was not a mediator however; males, minorities and those with less education were less likely to have had previous contact. Results indicated a need to emphasize the probability of recovering from a mental health condition when developing target-specific stigma reducing strategies.

  10. Non-Contact Detection of Breathing Using a Microwave Sensor

    PubMed Central

    Dei, Devis; Grazzini, Gilberto; Luzi, Guido; Pieraccini, Massimiliano; Atzeni, Carlo; Boncinelli, Sergio; Camiciottoli, Gianna; Castellani, Walter; Marsili, Massimo; Dico, Juri Lo

    2009-01-01

    In this paper the use of a continuous-wave microwave sensor as a non-contact tool for quantitative measurement of respiratory tidal volume has been evaluated by experimentation in seventeen healthy volunteers. The sensor working principle is reported and several causes that can affect its response are analyzed. A suitable data processing has been devised able to reject the majority of breath measurements taken under non suitable conditions. Furthermore, a relationship between microwave sensor measurements and volume inspired and expired at quiet breathing (tidal volume) has been found. PMID:22574033

  11. Position Request | Center for Cancer Research

    Cancer.gov

    CCR Staff Only - Use this form (NIH login required) to advertise open training or career positions. You are required to list information about the position, as well as contact information so that potential applicants may reach you. Mandatory fields are marked by an asterisk (*). A confirmation e-mail will be sent to the address listed in the "Contact E-mail" field upon

  12. 75 FR 60457 - Notice of Public Information Collection(s) Being Reviewed by the Federal Communications...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-30

    ... burden for small business concerns with fewer than 25 employees. The FCC may not conduct or sponsor a... allowed by this notice, you should advise the FCC contact listed below as soon as possible. ADDRESSES... via email to [email protected]fcc.gov . FOR FURTHER INFORMATION CONTACT: Judith B. Herman, Office of Managing...

  13. 75 FR 66120 - Information Collection Sent to the Office of Management and Budget (OMB) for Approval; OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-27

    ...-mail). Please provide a copy of your comments to Hope Grey, Information Collection Clearance Officer, U...), or hope_grey@fws.gov (e-mail). FOR FURTHER INFORMATION CONTACT: To request additional information about this ICR, contact Hope Grey by mail or e-mail (see ADDRESSES) or by telephone at (703) 358-2482...

  14. 32 CFR 806.20 - Records of non-U.S. government source.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... ADMINISTRATION AIR FORCE FREEDOM OF INFORMATION ACT PROGRAM § 806.20 Records of non-U.S. government source. (a...-mail address of: their own FOIA office point of contact; the Air Force record OPR point of contact, the... 32 National Defense 6 2010-07-01 2010-07-01 false Records of non-U.S. government source. 806.20...

  15. 32 CFR 806.20 - Records of non-U.S. government source.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... ADMINISTRATION AIR FORCE FREEDOM OF INFORMATION ACT PROGRAM § 806.20 Records of non-U.S. government source. (a...-mail address of: their own FOIA office point of contact; the Air Force record OPR point of contact, the... 32 National Defense 6 2011-07-01 2011-07-01 false Records of non-U.S. government source. 806.20...

  16. 32 CFR 806.20 - Records of non-U.S. government source.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... ADMINISTRATION AIR FORCE FREEDOM OF INFORMATION ACT PROGRAM § 806.20 Records of non-U.S. government source. (a...-mail address of: their own FOIA office point of contact; the Air Force record OPR point of contact, the... 32 National Defense 6 2013-07-01 2013-07-01 false Records of non-U.S. government source. 806.20...

  17. A contact stress model for multifingered grasps of rough objects

    NASA Technical Reports Server (NTRS)

    Sinha, Pramath Raj; Abel, Jacob M.

    1990-01-01

    The model developed utilizes a contact-stress analysis of an arbitrarily shaped object in a multifingered grasp. The fingers and the object are all treated as elastic bodies, and the region of contact is modeled as a deformable surface patch. The relationship between the friction and normal forces is nonlocal and nonlinear in nature and departs from the Coulomb approximation. The nature of the constraints arising out of conditions for compatibility and static equilibrium motivated the formulation of the model as a nonlinear constrained minimization problem. The model is able to predict the magnitude of the inwardly directed normal forces and both the magnitude and direction of the tangential (friction) forces at each finger-object interface for grasped objects in static equilibrium.

  18. Interictal spike detection comparing subdural and depth electrodes during electrocorticography.

    PubMed

    Privitera, M D; Quinlan, J G; Yeh, H S

    1990-11-01

    We compared the ability of subdural and depth electrodes to detect and localize interictal epileptiform discharges (IEDs) in the temporal lobe. Sixteen patients had simultaneous intraoperative recordings with depth and subdural electrodes while undergoing anterior temporal lobe resections under local anesthesia for medically intractable seizures. IEDs that were focal (detected at just 1 or 2 electrode contacts) typically registered at the nearest contact, regardless of type. IEDs that were regional (engaging more than 2 electrode contacts) typically appeared simultaneously at both electrode types. Neither method was better able to indicate whether an IED was mesial or lateral, posterior or anterior. Subdural and depth electrodes seem to provide complementary information on the location of IEDs within the temporal lobe.

  19. The influence of tyre contact patch and on the stopping distance of automotive vehicles

    NASA Astrophysics Data System (ADS)

    Selig, M.; Ball, A.; Ash, J.; Schmidt, K.

    2012-05-01

    This contribution presents the experimental tests results about the influence of the tyre contact patch on the stopping distance of automotive vehicles. The objective of the performed tests is the evaluation of the effect of tyre inflation pressure, hence the resulting tyre contact patch on the braking system and the brake distance. The conditions of the experiment are a dry and level road surface without steering inputs. To record scientific results, a brake robot system is used. The benefit of a robotic system is the elimination of the interfering variable driver, who is not able to apply the brake system at the same time with the same force. State-of-the-art data acquisition tools are used to log the data.

  20. Color-gradient lattice Boltzmann model for simulating droplet motion with contact-angle hysteresis.

    PubMed

    Ba, Yan; Liu, Haihu; Sun, Jinju; Zheng, Rongye

    2013-10-01

    Lattice Boltzmann method (LBM) is an effective tool for simulating the contact-line motion due to the nature of its microscopic dynamics. In contact-line motion, contact-angle hysteresis is an inherent phenomenon, but it is neglected in most existing color-gradient based LBMs. In this paper, a color-gradient based multiphase LBM is developed to simulate the contact-line motion, particularly with the hysteresis of contact angle involved. In this model, the perturbation operator based on the continuum surface force concept is introduced to model the interfacial tension, and the recoloring operator proposed by Latva-Kokko and Rothman is used to produce phase segregation and resolve the lattice pinning problem. At the solid surface, the color-conserving wetting boundary condition [Hollis et al., IMA J. Appl. Math. 76, 726 (2011)] is applied to improve the accuracy of simulations and suppress spurious currents at the contact line. In particular, we present a numerical algorithm to allow for the effect of the contact-angle hysteresis, in which an iterative procedure is used to determine the dynamic contact angle. Numerical simulations are conducted to verify the developed model, including the droplet partial wetting process and droplet dynamical behavior in a simple shear flow. The obtained results are compared with theoretical solutions and experimental data, indicating that the model is able to predict the equilibrium droplet shape as well as the dynamic process of partial wetting and thus permits accurate prediction of contact-line motion with the consideration of contact-angle hysteresis.

  1. How pinning and contact angle hysteresis govern quasi-static liquid drop transfer.

    PubMed

    Chen, H; Tang, T; Zhao, H; Law, K-Y; Amirfazli, A

    2016-02-21

    This paper presents both experimental and numerical simulations of liquid transfer between two solid surfaces with contact angle hysteresis (CAH). Systematic studies on the role of the advancing contact angle (θa), receding contact angle (θr) and CAH in determining the transfer ratio (volume of the liquid transferred onto the acceptor surface over the total liquid volume) and the maximum adhesion force (Fmax) were performed. The transfer ratio was found to be governed by contact line pinning at the end of the transfer process caused by CAH of surfaces. A map based on θr of the two surfaces was generated to identify the three regimes for liquid transfer: (I) contact line pinning occurs only on the donor surface, (II) contact line pinning occurs on both surfaces, and (III) contact line pinning occurs only on the acceptor surface. With this map, an empirical equation is provided which is able to estimate the transfer ratio by only knowing θr of the two surfaces. The value of Fmax is found to be strongly influenced by the contact line pinning in the early stretching stage. For symmetric liquid bridges between two identical surfaces, Fmax may be determined only by θa, only by θr, or by both θa and θr, depending on the magnitude of the contact angles. For asymmetric bridges, Fmax is found to be affected by the period when contact lines are pinned on both surfaces.

  2. Children's Writer's and Illustrator's Market.

    ERIC Educational Resources Information Center

    Buening, Alice P., Ed.

    The 1997 edition of this annual directory contains more than 800 listings in the children's book market; more than 150 of these listings are new with this edition, and nearly all the listings have been updated. The directory provides the standard addresses, contacts and query tips, but it also offers the publishers' electronic mail addresses and…

  3. 40 CFR 124.207 - What are the requirements for public notices?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... telephone number of your contact office, and a mailing address to which people may direct comments, information, opinions, or inquiries. (3) An address to which people may write to be put on the facility mailing list. (4) The location where people may view and make copies of the draft standardized permit and...

  4. 75 FR 8155 - Sunshine Act; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-23

    ... meeting will be webcast live at the Web address--http:// www.nrc.gov 9:30 a.m. Briefing on Decommissioning Funding (Public Meeting) (Contact: Thomas Fredrichs, 301-415-5971). This meeting will be webcast live at... meeting will be webcast live at the Web address-- http://www.nrc.gov . Week of March 8, 2010--Tentative...

  5. 77 FR 30331 - Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-22

    ...) (Contact: Rani Franovich, 301-415-1868). This meeting will be webcast live at the Web address--www.nrc.gov... will be webcast live at the Web address--www.nrc.gov. Week of June 11, 2012--Tentative Friday, June 15... Regulatory Commission (NRC) on Grid Reliability (Public Meeting) To be held at FERC Headquarters, 888 First...

  6. 75 FR 6413 - Sunshine Act Meeting Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-09

    ... Barkley, 610-337- 5065.) This meeting will be webcast live at the Web address-- http://www.nrc.gov . Week..., 301-251-7982.) This meeting will be webcast live at the Web address-- http://www.nrc.gov . Week of... (Public Meeting). (Contact: Thomas Fredrichs, 301-415-5971.) This meeting will be webcast live at the Web...

  7. 78 FR 48601 - Time Limit for Completion of Voluntary Self-Disclosures and Revised Notice of the Institution of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-09

    ... violations, including providing all relevant documentation. If the person making the initial notification... contain. Such requests should show specifically that the person making the request: (1) Began its review... person, and provide that contact person's current business street address, email address, and telephone...

  8. 40 CFR 150.17 - Addresses for the Office of Pesticide Programs.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    .... Publicly available docket materials are available in the electronic docket at http://www.regulations.gov. Although listed in the docket index at regulations.gov, some information is not publicly available, e.g... address. For instructions on visiting the docket, go to http://www.epa.gov/dockets/contacts.htm. (3...

  9. 40 CFR 150.17 - Addresses for the Office of Pesticide Programs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    .... Publicly available docket materials are available in the electronic docket at http://www.regulations.gov. Although listed in the docket index at regulations.gov, some information is not publicly available, e.g... address. For instructions on visiting the docket, go to http://www.epa.gov/dockets/contacts.htm. (3...

  10. 78 FR 11996 - Proposed Modification of Class D and Class E Airspace; Pueblo, CO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-21

    ... comments through the Internet at http://www.regulations.gov . FOR FURTHER INFORMATION CONTACT: Eldon Taylor... aspects of the proposal. Communications should identify both docket numbers (FAA Docket No. FAA 2012-0371... ADDRESSES section for address and phone number). You may also submit comments through the Internet at http...

  11. 76 FR 14061 - Notice of Inventory Completion: Denver Museum of Nature & Science, Denver, CO

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-15

    ... Museum of Nature & Science, Denver, CO AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The Denver Museum of Nature & Science has completed an inventory of human remains and associated... contact the Denver Museum of Nature & Science at the address below by April 14, 2011. ADDRESSES: Dr. Chip...

  12. 30 CFR 1204.205 - How do I obtain accounting and auditing relief?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., ONRR-assigned payor code, address, phone number, and contact name; and (ii) The specific ONRR lease number and agreement number, if applicable. (2) You may file a single notification for multiple marginal.... (1) Your request must contain: (i) Your company name, ONRR-assigned payor code, address, phone number...

  13. Schools and Programs in the United States.

    ERIC Educational Resources Information Center

    American Annals of the Deaf, 2000

    2000-01-01

    This annual directory lists U.S. schools and programs enrolling deaf and hard of hearing children and youth in two sections: (1) the directory listing including name, address, phone numbers, administrator or contact person, and e-mail/Web address and (2) program and services chart including whether day or residential, enrollment, services, and…

  14. Contact Us | Geospatial Data Science | NREL

    Science.gov Websites

    provide your name, email address, and message below. When you are finished, click "Send Message." ; NOTE: If you enter your email address incorrectly, we will be unable to reply. If you see this don't fill out this input box. Your Name * Your Email * Your Message * Submit

  15. Contact Us | Wind | NREL

    Science.gov Websites

    provide your name, email address, and message below. When you are finished, click "Send Message." ; NOTE: If you enter your email address incorrectly, we will be unable to reply. If you see this don't fill out this input box. Your Name* Your Email* Your Message* Form UUID Site Name Submit Clear

  16. 75 FR 36388 - Proposed Administrative Cost Recovery Settlement Under Section 122(h) of the Comprehensive...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-25

    ... addressed to: Dan Breedlove, Assistant Regional Counsel, Office of Regional Counsel, 901 N. 5th Street, Kansas City, Kansas 66101. FOR FURTHER INFORMATION CONTACT: Dan Breedlove, at telephone: (913) 551-7172; fax number: (913) 551-7925/Attn: Dan Breedlove; E-mail address: http: //www.breedlove.dan@epa.gov...

  17. Current Quality-of-Life Tools Available for Use in Contact Dermatitis.

    PubMed

    Swietlik, Jacquelyn; Reeder, Margo

    2016-01-01

    Contact dermatitis is a common dermatologic condition that can cause significant impairment in patients' overall quality of life (QoL). This impact is separate and potentially more clinically relevant than one's disease "severity" in contact dermatitis and should be consistently addressed by dermatologists. Despite this, QoL tools specific to contact dermatitis are lacking, and there is little consistency in the literature regarding the tool used to evaluate clinical response to therapies. Measurements currently available to evaluate disease-related QoL in contact dermatitis fit into 1 of the following 3 general types: generic health-related QoL measures, dermatology-related QoL measures, or specific dermatologic disease-related QoL measures. This article reviews the strengths and weaknesses of existing QoL tools used in contact dermatitis including: Short Form Survey 36, Dermatology Life Quality Index, Skindex-29, Skindex-16, Dermatology-Specific Quality of Life, and Fragrance Quality of Life Index.

  18. Age, gender, social contacts, and psychological distress: findings from the 45 and up study.

    PubMed

    Phongsavan, Philayrath; Grunseit, Anne C; Bauman, Adrian; Broom, Dorothy; Byles, Julie; Clarke, Judith; Redman, Sally; Nutbeam, Don

    2013-09-01

    The study examined the relationships between social contact types and psychological distress among mid-older adults. Self-completed data from 236,490 Australian adults aged 45+ years. There was a consistent relationship between increased frequency in phone contacts, social visits, and social group contacts and reduced risk of psychological distress adjusted for demographic and health factors. However, stratified analyses by age showed, with one exception, that no significant associations were found between social group contact frequency and risk of psychological distress for those aged 85 years and older. Furthermore, significant interaction terms revealed that women experience a steeper reduction in risk than men at age 65 to 74 years and 75 to 84 years compared with those aged 45 to 64 years. Social contacts have age and gender differential effects on psychological distress of mid-older Australian adults. Interventions addressing social interaction need to be sensitive to gender and age differences.

  19. Update: Advancement of Contact Dynamics Modeling for Human Spaceflight Simulation Applications

    NASA Technical Reports Server (NTRS)

    Brain, Thomas A.; Kovel, Erik B.; MacLean, John R.; Quiocho, Leslie J.

    2017-01-01

    Pong is a new software tool developed at the NASA Johnson Space Center that advances interference-based geometric contact dynamics based on 3D graphics models. The Pong software consists of three parts: a set of scripts to extract geometric data from 3D graphics models, a contact dynamics engine that provides collision detection and force calculations based on the extracted geometric data, and a set of scripts for visualizing the dynamics response with the 3D graphics models. The contact dynamics engine can be linked with an external multibody dynamics engine to provide an integrated multibody contact dynamics simulation. This paper provides a detailed overview of Pong including the overall approach and modeling capabilities, which encompasses force generation from contact primitives and friction to computational performance. Two specific Pong-based examples of International Space Station applications are discussed, and the related verification and validation using this new tool are also addressed.

  20. 75 FR 51041 - FIFRA Scientific Advisory Panel; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-18

    ... public process provided only for convenience. If difficulties arise resulting in webcasting outages, the... comment due to technical difficulties and cannot contact you for clarification, EPA may not be able to..., Office of Science Coordination and Policy (7201M), [[Page 51042

  1. Effect of Complete Syndesmotic Disruption and Deltoid Injuries and Different Reduction Methods on Ankle Joint Contact Mechanics.

    PubMed

    LaMothe, Jeremy; Baxter, Josh R; Gilbert, Susannah; Murphy, Conor I; Karnovsky, Sydney C; Drakos, Mark C

    2017-06-01

    Syndesmotic injuries can be associated with poor patient outcomes and posttraumatic ankle arthritis, particularly in the case of malreduction. However, ankle joint contact mechanics following a syndesmotic injury and reduction remains poorly understood. The purpose of this study was to characterize the effects of a syndesmotic injury and reduction techniques on ankle joint contact mechanics in a biomechanical model. Ten cadaveric whole lower leg specimens with undisturbed proximal tibiofibular joints were prepared and tested in this study. Contact area, contact force, and peak contact pressure were measured in the ankle joint during simulated standing in the intact, injured, and 3 reduction conditions: screw fixation with a clamp, screw fixation without a clamp (thumb technique), and a suture-button construct. Differences in these ankle contact parameters were detected between conditions using repeated-measures analysis of variance. Syndesmotic disruption decreased tibial plafond contact area and force. Syndesmotic reduction did not restore ankle loading mechanics to values measured in the intact condition. Reduction with the thumb technique was able to restore significantly more joint contact area and force than the reduction clamp or suture-button construct. Syndesmotic disruption decreased joint contact area and force. Although the thumb technique performed significantly better than the reduction clamp and suture-button construct, syndesmotic reduction did not restore contact mechanics to intact levels. Decreased contact area and force with disruption imply that other structures are likely receiving more loads (eg, medial and lateral gutters), which may have clinical implications such as the development of posttraumatic arthritis.

  2. 75 FR 9591 - FirstLight Hydro Generating Company; Notice of Application for Amendment of License and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-03

    ...: Federal Power Act, 16 U.S.C. 791(a)-825(r). h. Applicant Contact: Mr. Robert Gates, Station Manager-Connecticut Hydro, 143 West St., Ext. Suite E, New Milford, CT 06776, (860) 350- 3617. i. FERC Contact: Any questions on this notice should be addressed to Isis Johnson at (202) 502-6346, or by e-mail: Isis.Johnson...

  3. 76 FR 63327 - Shipyard Employment Standards; Extension of the Office of Management and Budget's (OMB) Approval...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-10-12

    ... copying at the OSHA Docket Office. You may also contact Theda Kenney at the address below to obtain a copy of the ICR. FOR FURTHER INFORMATION CONTACT: Theda Kenney or Todd Owen, Directorate of Standards and..., the angle upon which it is based, and the number of legs if more than one. Wire rope and wire-rope...

  4. The Moderating Effect of Valenced Contact: Slovak Language Media Use, Acculturation and L2 Confidence among Young Hungarian Speakers

    ERIC Educational Resources Information Center

    Vincze, Laszlo; Gasiorek, Jessica

    2016-01-01

    Integrating the tenets of the social context model of L2 acquisition with insights from the parasocial contact hypothesis, the present paper addresses the role of mass media in L2 acquisition and acculturation among young Hungarian speakers in Slovakia. Questionnaire data were collected among Hungarian-speaking secondary school students (N = 310).…

  5. Direct Health Care Provider Program

    DTIC Science & Technology

    1994-06-07

    C . Report’s Point of Contact: (Name, Organization, Address, Office Symbol, & Ph #): OAIG-AUD (ATTN: AFTS Audit Suggestions) Inspector General...James Beach, Audit Project Manager, at (804) 766-3292. The distribution of this report is listed in Appendix C . The audit team members are listed...Reviewed 14 Appendix B. Organizations Visited or Contacted 15 Appendix C . Report Distribution 16 Part IV - Management Comments 19 Deputy Assistant

  6. Mitigation of epidemics in contact networks through optimal contact adaptation *

    PubMed Central

    Youssef, Mina; Scoglio, Caterina

    2013-01-01

    This paper presents an optimal control problem formulation to minimize the total number of infection cases during the spread of susceptible-infected-recovered SIR epidemics in contact networks. In the new approach, contact weighted are reduced among nodes and a global minimum contact level is preserved in the network. In addition, the infection cost and the cost associated with the contact reduction are linearly combined in a single objective function. Hence, the optimal control formulation addresses the tradeoff between minimization of total infection cases and minimization of contact weights reduction. Using Pontryagin theorem, the obtained solution is a unique candidate representing the dynamical weighted contact network. To find the near-optimal solution in a decentralized way, we propose two heuristics based on Bang-Bang control function and on a piecewise nonlinear control function, respectively. We perform extensive simulations to evaluate the two heuristics on different networks. Our results show that the piecewise nonlinear control function outperforms the well-known Bang-Bang control function in minimizing both the total number of infection cases and the reduction of contact weights. Finally, our results show awareness of the infection level at which the mitigation strategies are effectively applied to the contact weights. PMID:23906209

  7. Mitigation of epidemics in contact networks through optimal contact adaptation.

    PubMed

    Youssef, Mina; Scoglio, Caterina

    2013-08-01

    This paper presents an optimal control problem formulation to minimize the total number of infection cases during the spread of susceptible-infected-recovered SIR epidemics in contact networks. In the new approach, contact weighted are reduced among nodes and a global minimum contact level is preserved in the network. In addition, the infection cost and the cost associated with the contact reduction are linearly combined in a single objective function. Hence, the optimal control formulation addresses the tradeoff between minimization of total infection cases and minimization of contact weights reduction. Using Pontryagin theorem, the obtained solution is a unique candidate representing the dynamical weighted contact network. To find the near-optimal solution in a decentralized way, we propose two heuristics based on Bang-Bang control function and on a piecewise nonlinear control function, respectively. We perform extensive simulations to evaluate the two heuristics on different networks. Our results show that the piecewise nonlinear control function outperforms the well-known Bang-Bang control function in minimizing both the total number of infection cases and the reduction of contact weights. Finally, our results show awareness of the infection level at which the mitigation strategies are effectively applied to the contact weights.

  8. 75 FR 11175 - Pesticide Products; Registration Applications

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-10

    ... comment due to technical difficulties and cannot contact you for clarification, EPA may not be able to... the document by docket ID number and other identifying information (subject heading, Federal Register...). 4. File Symbol: 5481-LAI. Docket Number: EPA-HQ-OPP-2010-0064. Applicant: Technology Sciences Group...

  9. 75 FR 66089 - FIFRA Scientific Advisory Panel; Notice of Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-27

    ... supplementary public process provided only for convenience. If difficulties arise resulting in webcasting... comment due to technical difficulties and cannot contact you for clarification, EPA may not be able to..., Office of Science Coordination and Policy (7201M), Environmental Protection Agency, 1200 Pennsylvania Ave...

  10. Shaping Approach Responses as Intervention for Specific Phobia in a Child with Autism

    ERIC Educational Resources Information Center

    Ricciardi, Joseph N.; Luiselli, James K.; Camare, Marianne

    2006-01-01

    We evaluated contact desensitization (reinforcing approach responses) as intervention for specific phobia with a child diagnosed with autism. During hospital-based intervention, the boy was able to encounter previously avoided stimuli. Parental report suggested that results were maintained postdischarge. (Contains 1 figure.)

  11. 75 FR 54546 - Amendment of the Commission's Rules Governing Hearing Aid-Compatible Mobile Handsets

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-08

    ... revisions to the Commission's wireless hearing aid compatibility rules. The Commission initiates this proceeding to ensure that consumers with hearing loss are able to access wireless communications services.... FOR FURTHER INFORMATION CONTACT: John Borkowski, Wireless Telecommunications Bureau, (202) 418-0626, e...

  12. Using Mixed-Mode Contacts in Client Surveys: Getting More Bang for Your Buck

    ERIC Educational Resources Information Center

    Israel, Glenn D.

    2013-01-01

    Surveys are commonly used in Extension to identify client needs or evaluate program outcomes. This article examines how available email addresses can be incorporated into mixed-mode procedures for surveys. When mail and email addresses are used to implement a sequence of email and postal invitations in a mixed-mode survey, response rates were…

  13. Elections: DOD Needs More Comprehensive Planning to Address Military and Overseas Absentee Voting Challenges

    DTIC Science & Technology

    2016-04-01

    Acknowledgments Contact Acknowledgments Related GAO Products Page 75 GAO-16-378 DOD Overseas Absentee Voting U.S. Postal Service: Actions... Products Page 76 GAO-16-378 DOD Overseas Absentee Voting Election Reform: Nine States’ Experiences Implementing Federal Requirements for...ELECTIONS DOD Needs More Comprehensive Planning to Address Military and Overseas Absentee Voting Challenges

  14. 29 CFR 825.310 - Certification for leave taken to care for a covered servicemember (military caregiver leave).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...”) health care provider; (3) A DOD TRICARE network authorized private health care provider; or (4) A DOD non... name, address, and appropriate contact information (telephone number, fax number, and/or email address... provider; (iii) A DOD TRICARE network authorized private health care provider; or (iv) A DOD non-network...

  15. 29 CFR 825.310 - Certification for leave taken to care for a covered servicemember (military caregiver leave).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...”) health care provider; (3) A DOD TRICARE network authorized private health care provider; or (4) A DOD non... name, address, and appropriate contact information (telephone number, fax number, and/or email address... provider; (iii) A DOD TRICARE network authorized private health care provider; or (iv) A DOD non-network...

  16. 78 FR 11683 - Division of Federal Employees' Compensation, Proposed Extension of Existing Collection; Comment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-19

    ... concerning the proposed collection: Death Gratuity Forms (CA- 40, CA-41, and CA-42). A copy of the proposed information collection request can be obtained by contacting the office listed below in the addresses section of this Notice. DATES: Written comments must be submitted to the office listed in the addresses...

  17. Noninvasive Continuous Monitoring of Tear Glucose Using Glucose-Sensing Contact Lenses.

    PubMed

    Ascaso, Francisco J; Huerva, Valentín

    2016-04-01

    : The incidence of diabetes mellitus is dramatically increasing in the developed countries. Tight control of blood glucose concentration is crucial to diabetic patients to prevent microvascular complications. Self-monitoring of blood glucose is widely used for controlling blood glucose levels and usually performed by an invasive test using a portable glucometer. Many technologies have been developed over the past decades with the purpose of obtaining a continuous physiological glycemic monitoring. A contact lens is the ideal vehicle for continuous tear glucose monitoring of glucose concentration in tear film. There are several research groups that are working in the development of contact lenses with embedded biosensors for continuously and noninvasively monitoring tear glucose levels. Although numerous aspects must be improved, contact lens technology is one step closer to helping diabetic subjects better manage their condition, and these contact lenses will be able to measure the level of glucose in the wearer's tears and communicate the information to a mobile phone or computer. This article reviews studies on ocular glucose and its monitoring methods as well as the attempts to continuously monitor the concentration of tear glucose by using contact lens-based sensors.

  18. Mentalizing eye contact with a face on a video: Gaze direction does not influence autonomic arousal.

    PubMed

    Lyyra, Pessi; Myllyneva, Aki; Hietanen, Jari K

    2018-04-26

    Recent research has revealed enhanced autonomic and subjective responses to eye contact only when perceiving another live person. However, these enhanced responses to eye contact are abolished if the viewer believes that the other person is not able to look back at the viewer. We purported to investigate whether this "genuine" eye contact effect can be reproduced with pre-recorded videos of stimulus persons. Autonomic responses, gaze behavior, and subjective self-assessments were measured while participants viewed pre-recorded video persons with direct or averted gaze, imagined that the video person was real, and mentalized that the person could see them or not. Pre-recorded videos did not evoke similar physiological or subjective eye contact effect as previously observed with live persons, not even when the participants were mentalizing being seen by the person. Gaze tracking results showed, however, increased attention allocation to faces with direct gaze compared to averted gaze directions. The results suggest that elicitation of the physiological arousal in response to genuine eye contact seems to require spontaneous experience of seeing and of being seen by another individual. © 2018 Scandinavian Psychological Associations and John Wiley & Sons Ltd.

  19. Contact geometry and mechanics predict friction forces during tactile surface exploration.

    PubMed

    Janko, Marco; Wiertlewski, Michael; Visell, Yon

    2018-03-20

    When we touch an object, complex frictional forces are produced, aiding us in perceiving surface features that help to identify the object at hand, and also facilitating grasping and manipulation. However, even during controlled tactile exploration, sliding friction forces fluctuate greatly, and it is unclear how they relate to the surface topography or mechanics of contact with the finger. We investigated the sliding contact between the finger and different relief surfaces, using high-speed video and force measurements. Informed by these experiments, we developed a friction force model that accounts for surface shape and contact mechanical effects, and is able to predict sliding friction forces for different surfaces and exploration speeds. We also observed that local regions of disconnection between the finger and surface develop near high relief features, due to the stiffness of the finger tissues. Every tested surface had regions that were never contacted by the finger; we refer to these as "tactile blind spots". The results elucidate friction force production during tactile exploration, may aid efforts to connect sensory and motor function of the hand to properties of touched objects, and provide crucial knowledge to inform the rendering of realistic experiences of touch contact in virtual reality.

  20. Occupational allergic contact dermatitis caused by sterile non-latex protective gloves: clinical investigation and chemical analyses.

    PubMed

    Pontén, Ann; Hamnerius, Nils; Bruze, Magnus; Hansson, Christer; Persson, Christina; Svedman, Cecilia; Thörneby Andersson, Kirsten; Bergendorff, Ola

    2013-02-01

    An increased frequency of occupational contact hand dermatitis among surgical operating theatre personnel has been noticed. To evaluate patients with occupational contact dermatitis caused by their rubber gloves, and to describe a method for analysing the content of the allergens in the gloves. Patch tests were performed with the baseline series, a rubber chemical series, and the patients' own gloves. A method for analysing 1,3-diphenylguanidine (DPG) and cetylpyridinium chloride in the gloves was developed. Contact allergy to thiuram mix was found in 8 of 16 patients, whereas 12 of 16 patients reacted to DPG. In 7 of 8 patients, contact allergy to cetylpyridinium chloride was found. In the patients' gloves, cetylpyridinium chloride and DPG were detected at higher concentrations on the inside of the gloves than on the outside. Most patients had worked for decades in their present occupations, but their hand dermatitis had only been present for months. Contact allergy to DPG in gloves has been disputed, but, in this study, we were able to confirm the presence of DPG and cetylpyridinium chloride in the causative gloves by using a modified method for the analysis. The presence of these chemicals in gloves caused an increase in occupational contact dermatitis in surgical operating theatre personnel. © 2012 John Wiley & Sons A/S.

  1. Er:YAG and CTH:YAG laser radiation: contact versus non-contact enamel ablation and sonic-activated bulk composite placement

    NASA Astrophysics Data System (ADS)

    Buckova, M.; Kasparova, M.; Dostalova, T.; Jelinkova, H.; Sulc, J.; Nemec, M.; Fibrich, M.; Bradna, P.; Miyagi, M.

    2013-05-01

    Laser radiation can be used for effective caries removal and cavity preparation without significant thermal effects, collateral damage of tooth structure, or patient discomfort. The aim of this study was to compare the quality of tissue after contact or non-contact Er:YAG and CTH:YAG laser radiation ablation. The second goal was to increase the sealing ability of hard dental tissues using sonic-activated bulk filling material with change in viscosity during processing. The artificial caries was prepared in intact teeth to simulate a demineralized surface and then the Er:YAG or CTH:YAG laser radiation was applied. The enamel artificial caries was gently removed by the laser radiation and sonic-activated composite fillings were inserted. A stereomicroscope and then a scanning electron microscope were used to evaluate the enamel surface. Er:YAG contact mode ablation in enamel was quick and precise; the cavity was smooth with a keyhole shaped prism and rod relief arrangement without a smear layer. The sonic-activated filling material was consistently regularly distributed; no cracks or microleakage in the enamel were observed. CTH:YAG irradiation was able to clean but not ablate the enamel surface; in contact and also in non-contact mode there was evidence of melting and fusing of the enamel.

  2. Restoring speech perception with cochlear implants by spanning defective electrode contacts.

    PubMed

    Frijns, Johan H M; Snel-Bongers, Jorien; Vellinga, Dirk; Schrage, Erik; Vanpoucke, Filiep J; Briaire, Jeroen J

    2013-04-01

    Even with six defective contacts, spanning can largely restore speech perception with the HiRes 120 speech processing strategy to the level supported by an intact electrode array. Moreover, the sound quality is not degraded. Previous studies have demonstrated reduced speech perception scores (SPS) with defective contacts in HiRes 120. This study investigated whether replacing defective contacts by spanning, i.e. current steering on non-adjacent contacts, is able to restore speech recognition to the level supported by an intact electrode array. Ten adult cochlear implant recipients (HiRes90K, HiFocus1J) with experience with HiRes 120 participated in this study. Three different defective electrode arrays were simulated (six separate defective contacts, three pairs or two triplets). The participants received three take-home strategies and were asked to evaluate the sound quality in five predefined listening conditions. After 3 weeks, SPS were evaluated with monosyllabic words in quiet and in speech-shaped background noise. The participants rated the sound quality equal for all take-home strategies. SPS with background noise were equal for all conditions tested. However, SPS in quiet (85% phonemes correct on average with the full array) decreased significantly with increasing spanning distance, with a 3% decrease for each spanned contact.

  3. Wear simulation of apex seal in rotary engine under mixed lubrication

    NASA Astrophysics Data System (ADS)

    Jiang, Hanying; Zuo, Zhengxing; Liu, Jinxiang

    2018-05-01

    In this work, the wear of apex seal's running face under mixed lubrication is studied. Numerical simulation is carried out by employing the couple model of Reynolds equation, Greenwood and Tripp model and Archard's wear law. The simulation is performed both for one circle and multi circle. In the multi circle simulation, the change of contact position due to wear is considered. A method that is able to find the new contact position based on the updated apex seal's contour profile is proposed, validated and used. The result of multi circle simulation indicates that contact position changes obviously around the maximum swing angles both on leading and trailing sides with the increase number of circles. The wear depth distribution becomes more uniform with the increase of operation circle number.

  4. Computerized Design and Generation of Low-noise Helical Gears with Modified Surface Topology

    NASA Technical Reports Server (NTRS)

    Litvin, F. L.; Chen, N. X.; Lu, J.; Handschuh, R. F.

    1994-01-01

    An approach for design and generation of low-noise helical gears with localized bearing contact is proposed. The approach is applied to double circular arc helical gears and modified involute helical gears. The reduction of noise and vibration is achieved by application of a predesigned parabolic function of transmission errors that is able to absorb a discontinuous linear function of transmission errors caused by misalignment. The localization of the bearing contact is achieved by the mismatch of pinion-gear tooth surfaces. Computerized simulation of meshing and contact of the designed gears demonstrated that the proposed approach will produce a pair of gears that has a parabolic transmission error function even when misalignment is present. Numerical examples for illustration of the developed approach are given.

  5. A maximum entropy model for chromatin structure

    NASA Astrophysics Data System (ADS)

    Farre, Pau; Emberly, Eldon; Emberly Group Team

    The DNA inside the nucleus of eukaryotic cells shows a variety of conserved structures at different length scales These structures are formed by interactions between protein complexes that bind to the DNA and regulate gene activity. Recent high throughput sequencing techniques allow for the measurement both of the genome wide contact map of the folded DNA within a cell (HiC) and where various proteins are bound to the DNA (ChIP-seq). In this talk I will present a maximum-entropy method capable of both predicting HiC contact maps from binding data, and binding data from HiC contact maps. This method results in an intuitive Ising-type model that is able to predict how altering the presence of binding factors can modify chromosome conformation, without the need of polymer simulations.

  6. A nursing-centered treatment team in inpatient medical psychiatry.

    PubMed

    Norton, J W; Jones, R; Quarles, E; Danielle, J

    1999-04-01

    1. Nurses have the most extensive direct contact with their patients, yet in the traditional physician-centered model, they are often excluded from decision making. We have developed a new model of patient care with the nurse as the primary therapist and contact person, as well as the individual who cares for each patient's physical needs. 2. Out team approach improves efficiency, integration of care, and staff unity, which can be especially helpful for patients with personality disorders. 3. Patients appreciate the approach and are better able to increase focus on treatment when the physicians are not present in the ward.

  7. Tubular solid oxide fuel cell current collector

    DOEpatents

    Bischoff, Brian L.; Sutton, Theodore G.; Armstrong, Timothy R.

    2010-07-20

    An internal current collector for use inside a tubular solid oxide fuel cell (TSOFC) electrode comprises a tubular coil spring disposed concentrically within a TSOFC electrode and in firm uniform tangential electrical contact with the electrode inner surface. The current collector maximizes the contact area between the current collector and the electrode. The current collector is made of a metal that is electrically conductive and able to survive under the operational conditions of the fuel cell, i.e., the cathode in air, and the anode in fuel such as hydrogen, CO, CO.sub.2, H.sub.2O or H.sub.2S.

  8. Comparison of self-reported and observed water contact in an S. mansoni endemic village in Brazil.

    PubMed

    Friedman, J F; Kurtis, J D; McGarvey, S T; Fraga, A L; Silveira, A; Pizziolo, V; Gazzinelli, G; LoVerde, P; Corrêa-Oliveira, R

    2001-03-30

    Estimates of exposure are critical for immuno-epidemiologic and intervention studies in human schistosomiasis. Direct observation of human water contact patterns is both costly and time consuming. To address these issues, we determined whether individuals residing in a Schistosoma mansoni endemic village in Brazil could accurately self-report their water contact patterns. We compared the results of a water contact questionnaire to the present gold standard, direct observation of water contact in 86 volunteers, aged 8--29. We administered a survey to estimate volunteers' frequency and type of water contact and directly measured each volunteers' water contact patterns during 5 weeks of detailed water contact observations. We found a poor correlation between self reported frequency of contact and directly observed exposure (rho=0.119, P=NS). The questionnaire data was supplemented by information about average body surface area of exposure and duration of contact for specific activities derived from observations of this cohort. This 'supplemented questionnaire' data was significantly correlated with their exposure index (rho=0.227, P=0.05). It provides a starting point from which questionnaires may develop to provide a more cost-effective and less labor intensive method of assessing water contact exposure at the level of the individual.

  9. 75 FR 70256 - Tralomethrin; Notice of Receipt of Request To Voluntarily Cancel Pesticide Registrations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-17

    ... comment due to technical difficulties and cannot contact you for clarification, EPA may not be able to... docket ID number and other identifying information (subject heading, Federal Register date and page... registrant Bayer (Bayer CropScience LP and Bayer Environmental Science) to cancel certain tralomethrin...

  10. 42 CFR 102.32 - Benefits for lost employment income.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 102.32 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES VACCINES SMALLPOX... smallpox vaccine recipients or vaccinia contacts may be able to receive benefits for loss of employment... may pay benefits for lost employment income to the estate of a deceased smallpox vaccine recipient or...

  11. 42 CFR 102.32 - Benefits for lost employment income.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 102.32 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES VACCINES SMALLPOX... smallpox vaccine recipients or vaccinia contacts may be able to receive benefits for loss of employment... may pay benefits for lost employment income to the estate of a deceased smallpox vaccine recipient or...

  12. 42 CFR 102.32 - Benefits for lost employment income.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 102.32 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES VACCINES SMALLPOX... smallpox vaccine recipients or vaccinia contacts may be able to receive benefits for loss of employment... may pay benefits for lost employment income to the estate of a deceased smallpox vaccine recipient or...

  13. 42 CFR 102.32 - Benefits for lost employment income.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 102.32 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES VACCINES SMALLPOX... smallpox vaccine recipients or vaccinia contacts may be able to receive benefits for loss of employment... may pay benefits for lost employment income to the estate of a deceased smallpox vaccine recipient or...

  14. 42 CFR 102.32 - Benefits for lost employment income.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 102.32 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES VACCINES SMALLPOX... smallpox vaccine recipients or vaccinia contacts may be able to receive benefits for loss of employment... may pay benefits for lost employment income to the estate of a deceased smallpox vaccine recipient or...

  15. Cognitive stimulation therapy as a sustainable intervention for dementia in sub-Saharan Africa: Feasibility and clinical efficacy using a stepped-wedge design - ERRATUM.

    PubMed

    Paddick, Stella-Maria; Mkenda, Sarah; Mbowe, Godfrey; Kisoli, Aloyce; Gray, William K; Dotchin, Catherine L; Ternent, Laura; Ogunniyi, Adesola; Kissima, John; Olakehinde, Olaide; Mushi, Declare; Walker, Richard W

    2017-06-01

    In the above article (Paddick, 2017) The corresponding author's details were previously listed incorrectly. The correct details are; contact number +44 191 293 2709 and email address William.gray@nhct.nhs.uk. The original article has been updated with the correct contact details. The publishers apologise for any inconvenience and confusion this error has caused.

  16. FAA Statistical Handbook of Aviation, Calendar Year 1992

    DTIC Science & Technology

    1992-01-01

    INFORMATION GPO operates U.S. Government bookstores all around the country where you can browse through the shelves and take your books home with you...For more information, contact Superintendent of Documents, U.S. Government Printing Office ( GPO ), Washington, DC 20402, (202)783-3238 or contact any...of the following GPO Bookstores located throughout the United States. Addresses are listed below for ordering purposes. ATLANTA, GA LAUREL, MD Room

  17. Final Environmental Assessment for the First Air Force Air Operations Center, First Air Force Headquarters/Air Force Forces Center, and Highway 98 Overpass at Tyndall Air Force Base, Florida

    DTIC Science & Technology

    2004-01-01

    to contact Sandra Veazey at (850) 595-8300 for additional information on asbestos issues. The Florida Department of Transportation (FDOT) supports...The notification form for the Department can be found at the following web address:. The Air Force is advised to contact Sandra Veazey at (850) 595

  18. Virulence Associated Gene 8 of Bordetella pertussis Enhances Contact System Activity by Inhibiting the Regulatory Function of Complement Regulator C1 Inhibitor

    PubMed Central

    Hovingh, Elise S.; de Maat, Steven; Cloherty, Alexandra P. M.; Johnson, Steven; Pinelli, Elena; Maas, Coen; Jongerius, Ilse

    2018-01-01

    Bordetella pertussis is a Gram-negative bacterium and the causative agent of whooping cough. Whooping cough is currently re-emerging worldwide and, therefore, still poses a continuous global health threat. B. pertussis expresses several virulence factors that play a role in evading the human immune response. One of these virulence factors is virulence associated gene 8 (Vag8). Vag8 is a complement evasion molecule that mediates its effects by binding to the complement regulator C1 inhibitor (C1-INH). This regulatory protein is a fluid phase serine protease that controls proenzyme activation and enzyme activity of not only the complement system but also the contact system. Activation of the contact system results in the generation of bradykinin, a pro-inflammatory peptide. Here, the activation of the contact system by B. pertussis was explored. We demonstrate that recombinant as well as endogenous Vag8 enhanced contact system activity by binding C1-INH and attenuating its inhibitory function. Moreover, we show that B. pertussis itself is able to activate the contact system. This activation was dependent on Vag8 production as a Vag8 knockout B. pertussis strain was unable to activate the contact system. These findings show a previously overlooked interaction between the contact system and the respiratory pathogen B. pertussis. Activation of the contact system by B. pertussis may contribute to its pathogenicity and virulence. PMID:29915576

  19. Virulence Associated Gene 8 of Bordetella pertussis Enhances Contact System Activity by Inhibiting the Regulatory Function of Complement Regulator C1 Inhibitor.

    PubMed

    Hovingh, Elise S; de Maat, Steven; Cloherty, Alexandra P M; Johnson, Steven; Pinelli, Elena; Maas, Coen; Jongerius, Ilse

    2018-01-01

    Bordetella pertussis is a Gram-negative bacterium and the causative agent of whooping cough. Whooping cough is currently re-emerging worldwide and, therefore, still poses a continuous global health threat. B. pertussis expresses several virulence factors that play a role in evading the human immune response. One of these virulence factors is virulence associated gene 8 (Vag8). Vag8 is a complement evasion molecule that mediates its effects by binding to the complement regulator C1 inhibitor (C1-INH). This regulatory protein is a fluid phase serine protease that controls proenzyme activation and enzyme activity of not only the complement system but also the contact system. Activation of the contact system results in the generation of bradykinin, a pro-inflammatory peptide. Here, the activation of the contact system by B. pertussis was explored. We demonstrate that recombinant as well as endogenous Vag8 enhanced contact system activity by binding C1-INH and attenuating its inhibitory function. Moreover, we show that B. pertussis itself is able to activate the contact system. This activation was dependent on Vag8 production as a Vag8 knockout B. pertussis strain was unable to activate the contact system. These findings show a previously overlooked interaction between the contact system and the respiratory pathogen B. pertussis . Activation of the contact system by B. pertussis may contribute to its pathogenicity and virulence.

  20. Prediction of contact mechanics in metal-on-metal Total Hip Replacement for parametrically comprehensive designs and loads.

    PubMed

    Donaldson, Finn E; Nyman, Edward; Coburn, James C

    2015-07-16

    Manufacturers and investigators of Total Hip Replacement (THR) bearings require tools to predict the contact mechanics resulting from diverse design and loading parameters. This study provides contact mechanics solutions for metal-on-metal (MoM) bearings that encompass the current design space and could aid pre-clinical design optimization and evaluation. Stochastic finite element (FE) simulation was used to calculate the head-on-cup contact mechanics for five thousand combinations of design and loading parameters. FE results were used to train a Random Forest (RF) surrogate model to rapidly predict the contact patch dimensions, contact area, pressures and plastic deformations for arbitrary designs and loading. In addition to widely observed polar and edge contact, FE results included ring-polar, asymmetric-polar, and transitional categories which have previously received limited attention. Combinations of design and load parameters associated with each contact category were identified. Polar contact pressures were predicted in the range of 0-200 MPa with no permanent deformation. Edge loading (with subluxation) was associated with pressures greater than 500 MPa and induced permanent deformation in 83% of cases. Transitional-edge contact (with little subluxation) was associated with intermediate pressures and permanent deformation in most cases, indicating that, even with ideal anatomical alignment, bearings may face extreme wear challenges. Surrogate models were able to accurately predict contact mechanics 18,000 times faster than FE analyses. The developed surrogate models enable rapid prediction of MoM bearing contact mechanics across the most comprehensive range of loading and designs to date, and may be useful to those performing bearing design optimization or evaluation. Published by Elsevier Ltd.

  1. Contact binaries in the Trans-neptunian Belt

    NASA Astrophysics Data System (ADS)

    Thirouin, Audrey; Sheppard, Scott S.

    2017-10-01

    A contact binary is made up of two objects that are almost touching or in contact with each other. These systems have been found in the Near-Earth Object population, the main belt of asteroids, the Jupiter Trojans, the comet population and even in the Trans-neptunian belt.Several studies suggest that up to 30% of the Trans-Neptunian Objects (TNOs) could be contact binaries (Sheppard & Jewitt 2004, Lacerda 2011). Contact binaries are not resolvable with the Hubble Space Telescope because of the small separation between the system's components (Noll et al. 2008). Only lightcurves with a characteristic V-/U-shape at the minimum/maximum of brightness and a large amplitude can identify these contact binaries. Despite an expected high fraction of contact binaries, 2001 QG298 is the only confirmed contact binary in the Trans-Neptunian belt, and 2003 SQ317 is a candidate to this class of systems (Sheppard & Jewitt 2004, Lacerda et al. 2014).Recently, using the Lowell’s 4.3m Discovery Channel Telescope and the 6.5m Magellan Telescope, we started a search for contact binaries at the edge of our Solar System. So far, our survey focused on about 40 objects in different dynamical groups of the Trans-Neptunian belt for sparse or complete lightcurves. We report the discovery of 5 new potential contact binaries converting the current estimate of potential/confirmed contact binaries to 7 objects. With one epoch of observations per object, we are not able to model in detail the systems, but we derive estimate for basic information such as shape, size, density of both objects as well as the separation between the system’s components. In this work, we will present these new systems, their basic characteristics, and we will discuss the potential main reservoir of contact binaries in the Trans-neptunian belt.

  2. Airborne non-contact and contact broadband ultrasounds for frequency attenuation profile estimation of cementitious materials.

    PubMed

    Gosálbez, J; Wright, W M D; Jiang, W; Carrión, A; Genovés, V; Bosch, I

    2018-08-01

    In this paper, the study of frequency-dependent ultrasonic attenuation in strongly heterogeneous cementitious materials is addressed. To accurately determine the attenuation over a wide frequency range, it is necessary to have suitable excitation techniques. We have analysed two kinds of ultrasound techniques: contact ultrasound and airborne non-contact ultrasound. The mathematical formulation for frequency-dependent attenuation has been established and it has been revealed that each technique may achieve similar results but requires specific different calibration processes. In particular, the airborne non-contact technique suffers high attenuation due to energy losses at the air-material interfaces. Thus, its bandwidth is limited to low frequencies but it does not require physical contact between transducer and specimen. In contrast, the classical contact technique can manage higher frequencies but the measurement depends on the pressure between the transducer and the specimen. Cement specimens have been tested with both techniques and frequency attenuation dependence has been estimated. Similar results were achieved at overlapping bandwidth and it has been demonstrated that the airborne non-contact ultrasound technique could be a viable alternative to the classical contact technique. Copyright © 2018 Elsevier B.V. All rights reserved.

  3. U.S.-China Military Contacts: Issues for Congress

    DTIC Science & Technology

    2009-04-15

    NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS...SPONSORING/MONITORING AGENCY NAME( S ) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM( S ) 11. SPONSOR/MONITOR’S REPORT NUMBER( S ) 12. DISTRIBUTION...fighter collided with a U.S. Navy EP-3 reconnaissance plane over the South China Sea.6 Upon surviving the collision, the EP-3’ s crew made an emergency

  4. U.S.-China Military Contacts: Issues for Congress

    DTIC Science & Technology

    2009-03-19

    NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR( S ) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME( S ) AND ADDRESS...SPONSORING/MONITORING AGENCY NAME( S ) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM( S ) 11. SPONSOR/MONITOR’S REPORT NUMBER( S ) 12. DISTRIBUTION...2001, a PLA Navy F-8 fighter collided with a U.S. Navy EP-3 reconnaissance plane over the South China Sea.6 Upon surviving the collision, the EP-3’ s

  5. Optimizing pentacene thin-film transistor performance: Temperature and surface condition induced layer growth modification

    PubMed Central

    Lassnig, R.; Hollerer, M.; Striedinger, B.; Fian, A.; Stadlober, B.; Winkler, A.

    2015-01-01

    In this work we present in situ electrical and surface analytical, as well as ex situ atomic force microscopy (AFM) studies on temperature and surface condition induced pentacene layer growth modifications, leading to the selection of optimized deposition conditions and entailing performance improvements. We prepared p++-silicon/silicon dioxide bottom-gate, gold bottom-contact transistor samples and evaluated the pentacene layer growth for three different surface conditions (sputtered, sputtered + carbon and unsputtered + carbon) at sample temperatures during deposition of 200 K, 300 K and 350 K. The AFM investigations focused on the gold contacts, the silicon dioxide channel region and the highly critical transition area. Evaluations of coverage dependent saturation mobilities, threshold voltages and corresponding AFM analysis were able to confirm that the first 3–4 full monolayers contribute to the majority of charge transport within the channel region. At high temperatures and on sputtered surfaces uniform layer formation in the contact–channel transition area is limited by dewetting, leading to the formation of trenches and the partial development of double layer islands within the channel region instead of full wetting layers. By combining the advantages of an initial high temperature deposition (well-ordered islands in the channel) and a subsequent low temperature deposition (continuous film formation for low contact resistance) we were able to prepare very thin (8 ML) pentacene transistors of comparably high mobility. PMID:26543442

  6. Insertion torque recordings for the diagnosis of contact between orthodontic mini-implants and dental roots: a systematic review.

    PubMed

    Meursinge Reynders, Reint; Ladu, Luisa; Ronchi, Laura; Di Girolamo, Nicola; de Lange, Jan; Roberts, Nia; Plüddemann, Annette

    2016-03-31

    Most orthodontic mini-implants (OMIs) are inserted between dental roots. The prevalence of contacting these structures is high. Such contacts can cause permanent root damage and implant instability. Increased torque levels during implant insertion (the index test) could be a more accurate and immediate measure for diagnosing implant-root contact (the target condition) than radiographs (the reference standard) and could ultimately lead to a reduction or elimination of X-ray exposure. To address this issue, we asked three questions: (1) whether OMIs with root contact had higher insertion torque values than those without, (2) what is the accuracy of the index test compared with the reference standard to diagnose the target condition and what are the adverse effects of the index test, and (3) whether intermediate torque values have clinical diagnostic utility. Methods were conducted according to our published protocol, which was based on the PRISMA-P 2015 statement. We applied broad spectrum eligibility criteria that included randomized and non-randomized studies on clinical, animal, and cadaver models. Not including such models would be unethical because it could slow down knowledge creation on the adverse effects of implant insertion. We conducted searches in more than 40 electronic databases including MEDLINE and 10 journals were hand-searched. Grey literature and reference lists were also searched. All research procedures were conducted independently by three reviewers. Authors of selected studies were contacted to obtain additional information. Outcomes on the three different research models were analysed separately. Systematic error was assessed with the Cochrane 'Risk of bias tool' for non-randomized studies. One clinical, two animal, and two cadaver studies fulfilled the eligibility criteria of the first research question. All studies and subgroups demonstrated higher insertion torque values for OMIs with the target condition than those without. Mean differences (MD) between these effect estimates were statistically significant in one beagle model (MD, 4.64; 95 % CI, 3.50 to 5.79) and three subgroups of cadaver studies (MD, 2.70; 95 % CI, 1.42 to 3.98) (MD, 3.97; 95 % CI, 2.17 to 5.78) (MD, 0.93; 95 % CI, 0.67 to 1.20). Highest mean differences were identified in most self-drilling compared with pre-drilling groups. Clinical heterogeneity between studies was high, and many items were underreported. All studies except one cadaver study scored at least one domain as 'serious risk' of bias. No studies addressed the second research question. One cadaver study addressed the third question which showed the importance of recording torque levels during the entire implant insertion process. Responses of contacted authors were helpful, but often difficult to obtain. Implants fractured in one animal and in one cadaver model. All eligible studies scored higher insertion torque values for implants with root contact than those without, but none of these studies assessed the diagnostic accuracy of the index test. The inclusion of non-randomized and animal and cadaver models in this systematic review provided key findings that otherwise would have been wasted. Such studies are important in the context of the wide applicability of this test, the high prevalence of the target condition, and the underreporting of adverse effects of interventions. A protocol for a potential new diagnostic pathway was presented, and the importance of contacting authors was addressed. The applicability of the findings should be interpreted in the context of underreporting and the many limitations of the included studies.

  7. Matrix addressable vertical cavity surface emitting laser array

    NASA Astrophysics Data System (ADS)

    Orenstein, M.; von Lehmen, A. C.; Chang-Hasnain, C.; Stoffel, N. G.; Harbison, J. P.

    1991-02-01

    The design, fabrication and characterization of 1024-element matrix-addressable vertical-cavity surface-emitting laser (VCSEL) arrays are described. A strained InGaAs quantum-well VCSEL structure was grown by MBE, and an array of 32 x 32 lasers was defined using a proton implantation process. A matrix addressing architecture was employed, which enables the individual addressing of each of the 1024 lasers using only 64 electrical contacts. All the lasers in the array, measured after the laser definition step, were operating with fairly homogeneous characteristics; threshold current of 6.8 mA and output quantum differential efficiency of about 8 percent.

  8. 78 FR 8188 - Notice of Realty Action: Proposed (Non-Competitive) Direct Sale of Public Land in Carbon County, UT

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-05

    ... by March 22, 2013. ADDRESSES: Address all written comments concerning this notice to the BLM, Price Field Office, Attn: Connie Leschin, 125 S. 600 W., Price, Utah, 84501. FOR FURTHER INFORMATION CONTACT... survey of the said land, on file with the BLM. The proposed sale is in conformance with the BLM Price...

  9. 76 FR 18674 - Security Zones; Sector Southeastern New England Captain of the Port Zone

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-05

    ... address, or a phone number in the body of your document so that we can contact you if we have questions... enforcement agencies assisting the Coast Guard. These zones are needed to protect cruise ships and the public... 12, 2011. ADDRESSES: You may submit comments identified by docket number USCG- 2010-0803 using any...

  10. 75 FR 80040 - Manufacturing Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-21

    ..., developing and marketing programs in support of manufacturing industries, job creation in the manufacturing... relevant contact information such as mailing address, fax, e-mail, fixed and mobile phone numbers and...

  11. 78 FR 38075 - International Labor Comparisons

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-25

    .... ADDRESSES: Send inquiries to John Ruser, Office of Productivity and Technology, Bureau of Labor Statistics... FURTHER INFORMATION CONTACT: John Ruser, Office of Productivity and Technology, Bureau of Labor Statistics...

  12. 78 FR 44519 - Forest Resource Coordinating Committee

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-24

    ... the addresses below: Nominations sent via express mail or overnight courier service: Maya Solomon...; 1400 Independence Avenue SW., Washington, DC 20250-1123. FOR FURTHER INFORMATION CONTACT: Maya Solomon...

  13. Measurement of Respiration Rate and Depth Through Difference in Temperature Between Skin Surface and Nostril by Using Thermal Image.

    PubMed

    Jeong, Hieyong; Matsuura, Yutaka; Ohno, Yuko

    2017-01-01

    The purpose of the present study was to propose a method to measure a respiration rate (RR) and depth at once through difference in temperature between the skin surface and nostril by using a thermal image. Although there have been a lot of devices for contact RR monitoring, it was considered that the subjects could be inconvenienced by having the sensing device in contact with their body. Our algorithm enabled us to make a breathing periodic function (BPF) under the non-contact and non-invasive condition through temperature differences near the nostril during the breath. As a result, it was proved that our proposed method was able to classify differences in breathing pattern between normal, deep, and shallow breath (P < 0.001). These results lead us to conclude that the RR and depth is simultaneously measured by the proposed algorithm of BPF without any contact or invasive procedure.

  14. An Evolving Worldview: Making Open Source Easy

    NASA Astrophysics Data System (ADS)

    Rice, Z.

    2017-12-01

    NASA Worldview is an interactive interface for browsing full-resolution, global satellite imagery. Worldview supports an open data policy so that academia, private industries and the general public can use NASA's satellite data to address Earth science related issues. Worldview was open sourced in 2014. By shifting to an open source approach, the Worldview application has evolved to better serve end-users. Project developers are able to have discussions with end-users and community developers to understand issues and develop new features. Community developers are able to track upcoming features, collaborate on them and make their own contributions. Developers who discover issues are able to address those issues and submit a fix. This reduces the time it takes for a project developer to reproduce an issue or develop a new feature. Getting new developers to contribute to the project has been one of the most important and difficult aspects of open sourcing Worldview. After witnessing potential outside contributors struggle, a focus has been made on making the installation of Worldview simple to reduce the initial learning curve and make contributing code easy. One way we have addressed this is through a simplified setup process. Our setup documentation includes a set of prerequisites and a set of straightforward commands to clone, configure, install and run. This presentation will emphasize our focus to simplify and standardize Worldview's open source code so that more people are able to contribute. The more people who contribute, the better the application will become over time.

  15. Changes in Wetting Hysteresis During Bioremediation: Changes in fluid flow behavior monitored with low-frequency seismic attenuation

    NASA Astrophysics Data System (ADS)

    Wempe, W.; Spetzler, H.; Kittleson, C.; Pursley, J.

    2003-12-01

    We observed significant reduction in wetting hysteresis with time while a diesel-contaminated quartz crystal was dipped in and out of an oil-reducing bacteria solution. This wetting hysteresis is significantly greater than the wetting hysteresis when the diesel-contaminated quartz crystal is dipped in and out of (1) water, (2) diesel and (3) the bacterial food solution that does not contain bacteria. The reduction in wetting hysteresis of the bacteria solution on the quartz surface results from a reduction in the advancing contact angle formed at the air-liquid-quartz contact with time; the receding contact angle remains the same with time. Our results suggest that the bacteria solution moves across the quartz surface with less resistance after bioremediation has begun. These results imply that bioremediation may influence fluid flow behavior with time. For many fluid-solid systems there is a difference between the contact angle while a contact line advances and recedes across a solid surface; this difference is known as wetting hysteresis. Changes in wetting hysteresis can occur from changes in surface tension or the surface topography. Low contact angle values indicate that the liquid spreads or wets well, while high values indicate poor wetting or non-wetting. Contact angles are estimated in the lab by measuring the weight of the meniscus formed at the air-liquid-quartz interface and by knowing the fluid surface tension. In the lab, we have been able to use low-frequency seismic attenuation data to detect changes in the wetting characteristics of glass plates and of Berea sandstone. The accepted seismic attenuation mechanism is related to the loss of seismic energy due to the hysteresis of meniscus movement (wetting hysteresis) when a pore containing two fluids is stressed at very low frequencies (< 10 Hz). When fluid-fluid-solid systems that exhibit wettability hysteresis are stressed at low frequencies, we observe seismic attenuation, whereas in a system that does not exhibit wettability hysteresis we do not. From our wettability hysteresis results, we conclude that we may be able to monitor bioremediation progress using seismic attenuation data. We are measuring low-frequency seismic attenuation in the lab while flowing bacteria solution through Berea sandstone and we are testing this application in the field.

  16. Household knowledge, attitudes and practices related to pet contact and associated zoonoses in Ontario, Canada

    PubMed Central

    2012-01-01

    Background Many human infections are transmitted through contact with animals (zoonoses), including household pets. Although pet ownership is common in most countries and non-pet owners may have frequent contact with pets, there is limited knowledge of the public’s pet contact practices and awareness of zoonotic disease risks from pets. The objective of this study was to characterize the general public’s knowledge, attitudes and risks related to pet ownership and animal contact in southern Ontario, Canada. Methods A self-administered questionnaire was distributed to individuals at two multi-physician clinics in Waterloo, Ontario, Canada during 2010. A single adult from each household was invited to participate in the study. Results Seventy five percent (641/853) of individuals approached completed the questionnaire. Pet ownership and contact were common; 64% of participants had a pet in their household and 37% of non-pet owning households had a member with at least weekly animal contact outside the home. Pet ownership was high (55%) for households with individuals at higher risk for infections (i.e., < 5 yrs, ≥ 65 yrs, immunocompromised). Most respondents (64%) indicated that they had never received information regarding pet-associated disease risks. When given a list of 11 infectious pathogens, respondents were only able to correctly classify just over half on their potential to be transmitted from pets to people (mean 6.4); independently, pet owners and those who recalled receiving information in the past about this topic were able to make significantly more correct identifications. Pet (36%) and non-pet owning households (10%) reported dog or cat bites or scratches during the preceding year. Households with individuals at higher risk for an infection did not differ from the remaining households regarding their perceived disease risk of pets, zoonotic disease knowledge, recall of being asked by their medical provider if they owned any pets, or recall of having received information regarding pet-associated disease risks and preventive measures. Conclusions These results suggest that there is a need for accessible zoonotic disease information for both pet and non-owning households, with additional efforts made by veterinary, human and public health personnel. Immediate educational efforts directed toward households with individuals at higher risk to infections are especially needed. PMID:22831165

  17. The Atmospheric Boundary Layer

    NASA Astrophysics Data System (ADS)

    Garratt, J. R.

    1994-05-01

    A comprehensive and lucid account of the physics and dynamics of the lowest one to two kilometers of the Earth's atmosphere in direct contact with the Earth's surface, known as the atmospheric boundary layer (ABL). Dr. Garratt emphasizes the application of the ABL problems to numerical modeling of the climate, which makes this book unique among recent texts on the subject. He begins with a brief introduction to the ABL before leading to the development of mean and turbulence equations and the many scaling laws and theories that are the cornerstone of any serious ABL treatment. Modeling of the ABL is crucially dependent for its realism on the surface boundary conditions, so chapters four and five deal with aerodynamic and energy considerations, with attention given to both dry and wet land surfaces and the sea. The author next treats the structure of the clear-sky, thermally stratified ABL, including the convective and stable cases over homogeneous land, the marine ABL, and the internal boundary layer at the coastline. Chapter seven then extends this discussion to the cloudy ABL. This is particularly relevant to current research because the extensive stratocumulus regions over the subtropical oceans and stratus regions over the Arctic have been identified as key players in the climate system. In the final chapters, Dr. Garratt summarizes the book's material by discussing appropriate ABL and surface parameterization schemes in general circulation models of the atmosphere that are being used for climate stimulation.

  18. Redistribution of Adhesive Forces through Src/FAK Drives Contact Inhibition of Locomotion in Neural Crest.

    PubMed

    Roycroft, Alice; Szabó, András; Bahm, Isabel; Daly, Liam; Charras, Guillaume; Parsons, Maddy; Mayor, Roberto

    2018-06-04

    Contact inhibition of locomotion is defined as the behavior of cells to cease migrating in their former direction after colliding with another cell. It has been implicated in multiple developmental processes and its absence has been linked to cancer invasion. Cellular forces are thought to govern this process; however, the exact role of traction through cell-matrix adhesions and tension through cell-cell adhesions during contact inhibition of locomotion remains unknown. Here we use neural crest cells to address this and show that cell-matrix adhesions are rapidly disassembled at the contact between two cells upon collision. This disassembly is dependent upon the formation of N-cadherin-based cell-cell adhesions and driven by Src and FAK activity. We demonstrate that the loss of cell-matrix adhesions near the contact leads to a buildup of tension across the cell-cell contact, a step that is essential to drive cell-cell separation after collision. Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

  19. Perovskite Solar Cells with Large-Area CVD-Graphene for Tandem Solar Cells.

    PubMed

    Lang, Felix; Gluba, Marc A; Albrecht, Steve; Rappich, Jörg; Korte, Lars; Rech, Bernd; Nickel, Norbert H

    2015-07-16

    Perovskite solar cells with transparent contacts may be used to compensate for thermalization losses of silicon solar cells in tandem devices. This offers a way to outreach stagnating efficiencies. However, perovskite top cells in tandem structures require contact layers with high electrical conductivity and optimal transparency. We address this challenge by implementing large-area graphene grown by chemical vapor deposition as a highly transparent electrode in perovskite solar cells, leading to identical charge collection efficiencies. Electrical performance of solar cells with a graphene-based contact reached those of solar cells with standard gold contacts. The optical transmission by far exceeds that of reference devices and amounts to 64.3% below the perovskite band gap. Finally, we demonstrate a four-terminal tandem device combining a high band gap graphene-contacted perovskite top solar cell (Eg = 1.6 eV) with an amorphous/crystalline silicon bottom solar cell (Eg = 1.12 eV).

  20. Guidelines for the presentation of contact allergy case reports.

    PubMed

    Uter, Wolfgang; Goossens, An; Gonçalo, Margarida; Johansen, Jeanne D

    2017-02-01

    Case reports constitute a classic publication format that is being increasingly appreciated, for example because of its educational value. In the field of contact dermatitis research, case reports often serve as sentinel publications concerning new allergens, or new exposures to known allergens, or regarding other conditions leading to contact dermatitis. The CARE guideline published in 2013 addresses standardized and complete reporting of case reports in all fields of medicine. The present article takes up the CARE suggestions, and further specifies these in terms of application to case reports in the field of contact dermatitis. The objective of this structured guidance is to provide junior or inexperienced doctors and researchers with an annotated list, against which the fulfilment of essential or optional items of a complete, high-quality case report to be submitted to Contact Dermatitis or other journals can be checked. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  1. Optical Coherence Tomography–Enhanced Microlaryngoscopy: Preliminary Report of a Noncontact Optical Coherence Tomography System Integrated With a Surgical Microscope

    PubMed Central

    Vokes, David E.; Jackson, Ryan; Guo, Shuguang; Perez, Jorge A.; Su, Jianping; Ridgway, James M.; Armstrong, William B.; Chen, Zhongping; Wong, Brian J. F.

    2014-01-01

    Objectives Optical coherence tomography (OCT) is a new imaging modality that uses near-infrared light to produce cross-sectional images of tissue with a resolution approaching that of light microscopy. We have previously reported use of OCT imaging of the vocal folds (VFs) during direct laryngoscopy with a probe held in contact or near-contact with the VFs. This aim of this study was to develop and evaluate a novel OCT system integrated with a surgical microscope to allow hands-free OCT imaging of the VFs, which could be performed simultaneously with microscopic visualization. Methods We performed a prospective evaluation of a new method of acquiring OCT images of the VFs. Results An OCT system was successfully integrated with a surgical microscope to permit noncontact OCT imaging of the VFs of 10 patients. With this novel device we were able to identify VF epithelium and lamina propria; however, the resolution was reduced compared to that achieved with the standard contact or near-contact OCT. Conclusions Optical coherence tomography is able to produce high-resolution images of vocal fold mucosa to a maximum depth of 1.6 mm. It may be used in the diagnosis of VF lesions, particularly early squamous cell carcinoma, in which OCT can show disruption of the basement membrane. Mounting the OCT device directly onto the operating microscope allows hands-free noncontact OCT imaging and simultaneous conventional microscopic visualization of the VFs. However, the lateral resolution of the OCT microscope system is 50 µm, in contrast to the conventional handheld probe system (10 µm). Although such images at this resolution are still useful clinically, improved resolution would enhance the system’s performance, potentially enabling real-time OCT-guided microsurgery of the larynx. PMID:18700431

  2. 12 CFR 563.103 - Registration of mortgage loan originators.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... ASSOCIATIONS-OPERATIONS Registration of Residential Mortgage Loan Originators § 563.103 Registration of...) Principal business location address and business contact information; (D) Social security number; (E) Gender...

  3. 12 CFR 563.103 - Registration of mortgage loan originators.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ASSOCIATIONS-OPERATIONS Registration of Residential Mortgage Loan Originators § 563.103 Registration of...) Principal business location address and business contact information; (D) Social security number; (E) Gender...

  4. 12 CFR 563.103 - Registration of mortgage loan originators.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... ASSOCIATIONS-OPERATIONS Registration of Residential Mortgage Loan Originators § 563.103 Registration of...) Principal business location address and business contact information; (D) Social security number; (E) Gender...

  5. 75 FR 12507 - Manufacturing Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-16

    ... in the selection of Council members include candidates' proven experience in developing and marketing... contact information such as mailing address, fax, e-mail, fixed and mobile phone numbers and support staff...

  6. 77 FR 6535 - Notice of Intent To Seek Approval To Collect Information

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-08

    ... information from participants: Contact information, affiliation, and database searching experience... and fax numbers, and email address. Six questions are asked regarding: database searching experience...

  7. 76 FR 75797 - Transportation Conformity Rule: MOVES Regional Grace Period Extension

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-05

    ... INFORMATION CONTACT: Meg Patulski, State Measures and Transportation Planning Center, Environmental Protection...) 214-4052; email address: patulski.meg@epa.gov . SUPPLEMENTARY INFORMATION: Because EPA received...

  8. The First Test: Madison’s Strategy, The Constitution, and the War of 1812

    DTIC Science & Technology

    2010-06-01

    20-21. 15 Kohn, Eagle and Sword, 48. 16 Kohn, Eagle and Sword, 52, 41. 18 2. Not able to support war 3. Not able to prevent internal sedition ...economic depression in the 1810s to British commercial restrictions. While Congressional speeches did address Indian hostilities, the more dominant theme

  9. (Bad) Feelings about Meeting Them? Episodic and Chronic Intergroup Emotions Associated with Positive and Negative Intergroup Contact As Predictors of Intergroup Behavior

    PubMed Central

    Kauff, Mathias; Asbrock, Frank; Wagner, Ulrich; Pettigrew, Thomas F.; Hewstone, Miles; Schäfer, Sarina J.; Christ, Oliver

    2017-01-01

    Based on two cross-sectional probability samples (Study 1: N = 1,382, Study 2: N = 1,587), we studied the interplay between positive and negative intergroup contact, different types of intergroup emotions (i.e., episodic intergroup emotions encountered during contact and more general chronic intergroup emotions), and outgroup behavior in the context of intergroup relations between non-immigrant Germans and foreigners living in Germany. In Study 1, we showed that positive and negative contact are related to specific episodic intergroup emotions (i.e., anger, fear and happiness). Results of Study 2 indicate an indirect effect of episodic intergroup emotions encountered during contact experiences on specific behavioral tendencies directed at outgroup members via more chronic situation-independent intergroup emotions. As expected, anger predicted approaching (discriminatory) behavioral tendencies (i.e., aggression) while fear predicted avoidance. The results extend the existing literature on intergroup contact and emotions by addressing positive and negative contact simultaneously and differentiating between situation-specific episodic and chronic intergroup emotions in predicting discriminatory behavioral tendencies. PMID:28900403

  10. Long-term effect on mother-infant behaviour of extra contact during the first hour post partum. III. Follow-up at one year.

    PubMed

    de Château, P; Wiberg, B

    1984-01-01

    The present prospective study examined, one year after delivery, the possible effects of early extra contact during the first hour following delivery. An extra skin-to-skin contact and suckling contact was allowed 22 primiparous mothers and their infants (P + group). One control group of 20 primiparous mothers and their infants were given routine care immediately after birth (P group). During observation of a physical examination of the infant, 'extra contact mothers' held and touched their infants more frequently and more often talked positively to their infants than did mothers given routine care. 'Extra contact mothers' had returned to their professional employment outside the home to a lesser extent than had routine care mothers. A greater proportion of 'extra contact' infants slept in a room of their own. In the P+ group, mothers who had returned to gainful employment were also able to have their babies sleep in a room of their own--no such correspondence was found in the P group. The Gesell Developmental Schedules revealed that, in four parts out of five, infants with extra contact immediately after birth, were ahead of those in the control group. On the other hand, the Vineland Social Maturity Scale and the Cesarec Marke Personality Scheme did not reveal any major differences between the two groups. Mothers with early extra skin-to-skin contact and suckling contact breast-fed their infants on an average for 2 1/2 months longer than did routine care mothers. No other differences in feeding habits were found. The influence of extra contact was more pronounced in boy-mother than in girl-mother pairs.

  11. Contact Patterns among High School Students

    PubMed Central

    Fournet, Julie; Barrat, Alain

    2014-01-01

    Face-to-face contacts between individuals contribute to shape social networks and play an important role in determining how infectious diseases can spread within a population. It is thus important to obtain accurate and reliable descriptions of human contact patterns occurring in various day-to-day life contexts. Recent technological advances and the development of wearable sensors able to sense proximity patterns have made it possible to gather data giving access to time-varying contact networks of individuals in specific environments. Here we present and analyze two such data sets describing with high temporal resolution the contact patterns of students in a high school. We define contact matrices describing the contact patterns between students of different classes and show the importance of the class structure. We take advantage of the fact that the two data sets were collected in the same setting during several days in two successive years to perform a longitudinal analysis on two very different timescales. We show the high stability of the contact patterns across days and across years: the statistical distributions of numbers and durations of contacts are the same in different periods, and we observe a very high similarity of the contact matrices measured in different days or different years. The rate of change of the contacts of each individual from one day to the next is also similar in different years. We discuss the interest of the present analysis and data sets for various fields, including in social sciences in order to better understand and model human behavior and interactions in different contexts, and in epidemiology in order to inform models describing the spread of infectious diseases and design targeted containment strategies. PMID:25226026

  12. Thickness and topographic inspection of RPG contact lenses by optical triangulation

    NASA Astrophysics Data System (ADS)

    Costa, Manuel F. M.

    2001-06-01

    Optical triangulation as a non-destructive test method extensively proved its usefulness on the dimensional and topographic inspection of a large range of objects and surfaces. In this communication the issue of microtopographic and thickness inspection of hard contact lenses (RPG) is addressed. The use of optical triangulation is discussed based on the results of the application of our MICROTOP.03.MFC microtopographer to this kind of tasks will be presented.

  13. Communication with extraterrestrial intelligences - Possibilities, chances, and perspectives with special attention given to the leaky-embargo hypothesis

    NASA Astrophysics Data System (ADS)

    Fiebag, Johannes

    1989-12-01

    Present SETI projects are described, emphasizing search methods alternative to investigations in the radio range. The possibility that the human race is being studied by alien presences within the solar system is addressed in the context of the 'zoo hypothesis' and the 'leaky embargo' hypothesis. In the former, the aliens prevent any contact with humans, while in the latter occasional contact is permitted.

  14. Finding of No Significant Impact: First Air Force Air Operations Center, First Air Force Headquarters/Air Force Forces Center, and Highway 98 Overpass at Tyndall Air Force Base, Florida

    DTIC Science & Technology

    2004-11-10

    found at the following web address: <http://dep.state.fl.us/air/forms/asbestos.htm#asbestos>. The Air Force is advised to contact Sandra Veazey at...advised to contact Sandra Veazey at (850) 595·8300 for additional information on asbestos issues. http://tlhora6.dep.state.fl.us/clearinghouse/agency

  15. Reported Contact with the Dead, Religious Involvement, and Death Anxiety in Late Life

    PubMed Central

    Krause, Neal

    2010-01-01

    The purpose of this study is to examine the relationship between contact with the dead and death anxiety. The data come from an ongoing nationwide survey of older adults. A conceptual model is developed that contains the following theoretical linkages: (1) making contact with the dead instills a deeper appreciation of the connection that exists among all people; (2) this fundamental sense of connectedness with others fosters a deeper sense of religious meaning in life; and (3) individuals with a deeper sense of religious meaning in life are less likely to experience feelings of death anxiety than people who have not been able to find meaning in life through religion. The findings from this study provide support for each of these relationships. The theoretical implications of these hypotheses are discussed. PMID:21892231

  16. Using linear algebra for protein structural comparison and classification

    PubMed Central

    2009-01-01

    In this article, we describe a novel methodology to extract semantic characteristics from protein structures using linear algebra in order to compose structural signature vectors which may be used efficiently to compare and classify protein structures into fold families. These signatures are built from the pattern of hydrophobic intrachain interactions using Singular Value Decomposition (SVD) and Latent Semantic Indexing (LSI) techniques. Considering proteins as documents and contacts as terms, we have built a retrieval system which is able to find conserved contacts in samples of myoglobin fold family and to retrieve these proteins among proteins of varied folds with precision of up to 80%. The classifier is a web tool available at our laboratory website. Users can search for similar chains from a specific PDB, view and compare their contact maps and browse their structures using a JMol plug-in. PMID:21637532

  17. Using linear algebra for protein structural comparison and classification.

    PubMed

    Gomide, Janaína; Melo-Minardi, Raquel; Dos Santos, Marcos Augusto; Neshich, Goran; Meira, Wagner; Lopes, Júlio César; Santoro, Marcelo

    2009-07-01

    In this article, we describe a novel methodology to extract semantic characteristics from protein structures using linear algebra in order to compose structural signature vectors which may be used efficiently to compare and classify protein structures into fold families. These signatures are built from the pattern of hydrophobic intrachain interactions using Singular Value Decomposition (SVD) and Latent Semantic Indexing (LSI) techniques. Considering proteins as documents and contacts as terms, we have built a retrieval system which is able to find conserved contacts in samples of myoglobin fold family and to retrieve these proteins among proteins of varied folds with precision of up to 80%. The classifier is a web tool available at our laboratory website. Users can search for similar chains from a specific PDB, view and compare their contact maps and browse their structures using a JMol plug-in.

  18. Silicon chip with capacitors and transistors for interfacing organotypic brain slice of rat hippocampus.

    PubMed

    Hutzler, Michael; Fromherz, Peter

    2004-04-01

    Probing projections between brain areas and their modulation by synaptic potentiation requires dense arrays of contacts for noninvasive electrical stimulation and recording. Semiconductor technology is able to provide planar arrays with high spatial resolution to be used with planar neuronal structures such as organotypic brain slices. To address basic methodical issues we developed a silicon chip with simple arrays of insulated capacitors and field-effect transistors for stimulation of neuronal activity and recording of evoked field potentials. Brain slices from rat hippocampus were cultured on that substrate. We achieved local stimulation of the CA3 region by applying defined voltage pulses to the chip capacitors. Recording of resulting local field potentials in the CA1 region was accomplished with transistors. The relationship between stimulation and recording was rationalized by a sheet conductor model. By combining a row of capacitors with a row of transistors we determined a simple stimulus-response matrix from CA3 to CA1. Possible contributions of inhomogeneities of synaptic projection, of tissue structure and of neuroelectronic interfacing were considered. The study provides the basis for a development of semiconductor chips with high spatial resolution that are required for long-term studies of topographic mapping.

  19. [Establishment of an Animal Based Therapy at a University Hospital for Psychiatry: Results of a Preliminary Study and Future Prospects].

    PubMed

    Hartfiel, Cajetan; Bodatsch, Mitja; Klosterkötter, Joachim; Kuhn, Jens

    2017-01-01

    Objective: Dogs have been integrated in human society over centuries. This process has selected unique social and communicative skills. Dogs are thus able to represent social substitutes for human counterparts in cases of social withdrawal. Furthermore, dogs act as "social catalysts" in promoting interhuman encounters. Thus, the integration of dogs in psychotherapeutic concepts addressing social and interpersonal deficits may be of special interest. Methods: The present investigation reports the results of a pilot study to establish animal-assisted therapy (dogs) at a psychiatric department. The animal-assisted intervention straddled the following areas: (1) contact making, communication and orientation to needs, (2) recreation and play, (3) outward orientation, (4) release and farewell. The sample comprised 22 subjects. Results: The results demonstrated in particular that the animal-assisted intervention significantly promoted unspecific aspects of positive affectivity and wellbeing. Evaluation of the overall acceptance of the dog on the psychiatric ward revealed very positive feedback. Conclusions: We conclude that animal-assisted therapies represent a significant enchrichment of the therapeutic context, that may be used to enhance the patients' openness and adherence to conventional therapies. © Georg Thieme Verlag KG Stuttgart · New York.

  20. Free chlorine inactivation of fungi in drinking water sources.

    PubMed

    Pereira, V J; Marques, R; Marques, M; Benoliel, M J; Barreto Crespo, M T

    2013-02-01

    The effectiveness of free chlorine for the inactivation of fungi present in settled surface water was tested. In addition, free chlorine inactivation rate constants of Cladosporium tenuissimum, Cladosporium cladosporioides, Phoma glomerata, Aspergillus terreus, Aspergillus fumigatus, Penicillium griseofulvum, and Penicillium citrinum that were found to occur in different source waters were determined in different water matrices (laboratory grade water and settled water). The effect of using different disinfectant concentrations (1 and 3 mg/l), temperatures (21 and 4 °C), and pH levels (6 and 7) was addressed. The sensitivity degree of different fungi isolates to chlorine disinfection varied among different genera with some species showing a higher resistance to disinfection and others expected to be more prone to protection from inactivation by the water matrix components. When the disinfection efficiency measured in terms of the chlorine concentration and contact time (Ct) values needed to achieve 99% inactivation were compared with the Ct values reported as being able to achieve the same degree of inactivation of other microorganisms, fungi were found to be more resistant to chlorine inactivation than bacteria and viruses and less resistant than Cryptosporidium oocysts. Copyright © 2012 Elsevier Ltd. All rights reserved.

  1. Is there a doctor in the house? : The presence of physicians in the direct-to-consumer genetic testing context.

    PubMed

    Howard, Heidi Carmen; Borry, Pascal

    2012-04-01

    Over the last couple of years, many commercial companies, the majority of which are based in the USA, have been advertising and offering direct-to-consumer (DTC) genetic testing services outside of the established health care system, and often without any involvement from a health care professional. In the last year, however, a number of DTC genetic testing companies have changed their provision model such that consumers must now contact a health care professional before being able to order the genetic testing service. In discussing the advent of this new model of service provision, this article also reviews the ethical and social issues surrounding DTC genetic testing and addresses the potential motivations for change, some barriers to achieving truly appropriate medical supervision and the present reality of DTC genetic testing for some psychiatric and neurological disorders. Since the advent of these commercial activities, critics have pointed a finger at the lack of medical supervision surrounding these services. The discussion herein, however, reveals how difficult it may be, despite the addition of a physician, to actually achieve adequate medical supervision within the present context of DTC genetic testing.

  2. Active control of nanolitre droplet contents with convective concentration gradients across permeable walls.

    PubMed

    Zeitoun, Ramsey I; Goudie, Marcus J; Zwier, Jacob; Mahawilli, David; Burns, Mark A

    2011-12-07

    Nanolitre droplets in microfluidic devices can be used to perform thousands of independent chemical and biological experiments while minimizing reagents, cost and time. However, the absence of simple and versatile methods capable of controlling the contents of these nanolitre chemical systems limits their scientific potential. To address this, we have developed a method that is simple to fabricate and can continuously control nanolitre chemical systems by integrating a time-resolved convective flow signal across a permeable membrane wall. With this method, we can independently control the volume and concentration of nanolitre-sized drops without ever directly contacting the fluid. Transport occurring in these systems was also analyzed and thoroughly characterized. We achieved volumetric fluid introduction and removal rates ranging from 0.23 to 4.0 pL s(-1). Furthermore, we expanded this method to perform chemical processes. We precipitated silver chloride using a flow signal of sodium chloride and silver nitrate droplets. From there, we were able to separate sodium chloride reactants with a water flow signal, and dissolve silver chloride solids with an ammonia hydroxide flow signal. Finally, we demonstrate the potential to deliver large molecules and perform physical processes like crystallization and particle packing.

  3. MOLGENIS/connect: a system for semi-automatic integration of heterogeneous phenotype data with applications in biobanks

    PubMed Central

    Pang, Chao; van Enckevort, David; de Haan, Mark; Kelpin, Fleur; Jetten, Jonathan; Hendriksen, Dennis; de Boer, Tommy; Charbon, Bart; Winder, Erwin; van der Velde, K. Joeri; Doiron, Dany; Fortier, Isabel; Hillege, Hans

    2016-01-01

    Motivation: While the size and number of biobanks, patient registries and other data collections are increasing, biomedical researchers still often need to pool data for statistical power, a task that requires time-intensive retrospective integration. Results: To address this challenge, we developed MOLGENIS/connect, a semi-automatic system to find, match and pool data from different sources. The system shortlists relevant source attributes from thousands of candidates using ontology-based query expansion to overcome variations in terminology. Then it generates algorithms that transform source attributes to a common target DataSchema. These include unit conversion, categorical value matching and complex conversion patterns (e.g. calculation of BMI). In comparison to human-experts, MOLGENIS/connect was able to auto-generate 27% of the algorithms perfectly, with an additional 46% needing only minor editing, representing a reduction in the human effort and expertise needed to pool data. Availability and Implementation: Source code, binaries and documentation are available as open-source under LGPLv3 from http://github.com/molgenis/molgenis and www.molgenis.org/connect. Contact: m.a.swertz@rug.nl Supplementary information: Supplementary data are available at Bioinformatics online. PMID:27153686

  4. 76 FR 23646 - Privacy Act of 1974, as Amended; Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-27

    ... notice contained incorrect addresses. FOR FURTHER INFORMATION CONTACT: Dale Underwood, Privacy Act Officer, Department of the Treasury, (202)-622-0874 ( dale[email protected] ). Correction In the...

  5. 78 FR 27452 - Credit Ratings Roundtable

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-10

    ... regarding issues addressed at the roundtable until June 3, 2013. FOR FURTHER INFORMATION CONTACT: Scott Davey at (212) 336-0075, Office of Credit Ratings, Securities and Exchange Commission, 3 World Financial...

  6. Influence of Asymmetric Contact Form on Contact Resistance and Schottky Barrier, and Corresponding Applications of Diode.

    PubMed

    Zhao, Yudan; Xiao, Xiaoyang; Huo, Yujia; Wang, Yingcheng; Zhang, Tianfu; Jiang, Kaili; Wang, Jiaping; Fan, Shoushan; Li, Qunqing

    2017-06-07

    We have fabricated carbon nanotube and MoS 2 field-effect transistors with asymmetric contact forms of source-drain electrodes, from which we found the current directionality of the devices and different contact resistances under the two current directions. By designing various structures, we can conclude that the asymmetric electrical performance was caused by the difference in the effective Schottky barrier height (Φ SB ) caused by the different contact forms. A detailed temperature-dependent study was used to extract and compare the Φ SB for both contact forms of CNT and MoS 2 devices; we found that the Φ SB for the metal-on-semiconductor form was much lower than that of the semiconductor-on-metal form and is suitable for all p-type, n-type, or ambipolar semiconductors. This conclusion is meaningful with respect to the design and application of nanomaterial electronic devices. Additionally, using the difference in barrier height caused by the contact forms, we have also proposed and fabricated Schottky barrier diodes with a current ratio up to 10 4 ; rectifying circuits consisting of these diodes were able to work in a wide frequency range. This design avoided the use of complex chemical doping or heterojunction methods to achieve fundamental diodes that are relatively simple and use only a single material; these may be suitable for future application in nanoelectronic radio frequency or integrated circuits.

  7. 77 FR 15099 - Human Studies Review Board; Notification of a Public Webinar/Teleconference

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-14

    .... SUMMARY: The EPA Office of the Science Advisor announces a public Webinar/teleconference of the HSRB to... difficulties and cannot contact you for clarification, the EPA may not be able to consider your comment... Protection Agency, Office of the Science Advisor, Mail Code 8105R, 1200 Pennsylvania Avenue NW., Washington...

  8. 75 FR 24697 - Carbaryl; Notice of Receipt of Requests To Voluntarily Cancel Certain Pesticide Registrations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-05

    ... comment due to technical difficulties and cannot contact you for clarification, EPA may not be able to... the document by docket ID number and other identifying information (subject heading, Federal Register... requests from registrants Bayer Environmental Science and Bayer CropScience to cancel certain carbaryl...

  9. 75 FR 81711 - Notice of Receipt of Petition for Decision That Nonconforming 1991 Rice Beaufort Double Trailers...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-28

    ... reflectors, tail lamps, license plate lamps, rear side marker lamps, front side marker lamps, intermediate... information provided. Please see the Privacy Act heading below. Privacy Act: Anyone is able to search the... that you periodically search the Docket for new material. FOR FURTHER INFORMATION CONTACT: Coleman...

  10. The Role of Seating Position in Group Interaction: A Review, with Applications for Group Trainers

    ERIC Educational Resources Information Center

    Greenberg, Jerald

    1976-01-01

    Experimental research relating seating position to group interaction was critically reviewed. Studies have found that persons in central seating positions were able to maintain eye contact with the most group members, thereby enhancing their ability to interact with the group and emerge as the leader. (Author)

  11. Promoting Socialization in Distance Education

    ERIC Educational Resources Information Center

    Tucker, Shelia Y.

    2012-01-01

    Learners enjoy the convenience of being able to take online courses, yet many reports missing the face-to-face contact with their peers. This researcher has sought to tap into the vision of Ferratt & Hall (2009) whereby educators and technology designers are encouraged to extend the vision of online learning to "virtually being there and…

  12. All a Twitter: Want to Try Microblogging?

    ERIC Educational Resources Information Center

    Kroski, Ellyssa

    2008-01-01

    The author describes how she was able to broadcast her whereabouts, her moods, and her desire to connect with friends for dinner to over 150 conference attendees simultaneously, using her mobile phone through a service called Twitter. Twitter enables social butterflies like the author to instantly publish brief messages to a network of contacts.…

  13. Survival Strategies of Older Homeless Men.

    ERIC Educational Resources Information Center

    Cohen, Carl I.; And Others

    1988-01-01

    Examined how 281 homeless men aged 50 and older living on skid row were able to procure basic necessities such as money, food, shelter, and health care. Found men had and used informal supports to survive. Inability to fulfill needs was primarily associated with physical health, depression, lack of contacts with institutions and agencies, and…

  14. Insect adhesion on rough surfaces: analysis of adhesive contact of smooth and hairy pads on transparent microstructured substrates

    PubMed Central

    Zhou, Yanmin; Robinson, Adam; Steiner, Ullrich; Federle, Walter

    2014-01-01

    Insect climbing footpads are able to adhere to rough surfaces, but the details of this capability are still unclear. To overcome experimental limitations of randomly rough, opaque surfaces, we fabricated transparent test substrates containing square arrays of 1.4 µm diameter pillars, with variable height (0.5 and 1.4 µm) and spacing (from 3 to 22 µm). Smooth pads of cockroaches (Nauphoeta cinerea) made partial contact (limited to the tops of the structures) for the two densest arrays of tall pillars, but full contact (touching the substrate in between pillars) for larger spacings. The transition from partial to full contact was accompanied by a sharp increase in shear forces. Tests on hairy pads of dock beetles (Gastrophysa viridula) showed that setae adhered between pillars for larger spacings, but pads were equally unable to make full contact on the densest arrays. The beetles' shear forces similarly decreased for denser arrays, but also for short pillars and with a more gradual transition. These observations can be explained by simple contact models derived for soft uniform materials (smooth pads) or thin flat plates (hairy-pad spatulae). Our results show that microstructured substrates are powerful tools to reveal adaptations of natural adhesives for rough surfaces. PMID:24990289

  15. Insect adhesion on rough surfaces: analysis of adhesive contact of smooth and hairy pads on transparent microstructured substrates.

    PubMed

    Zhou, Yanmin; Robinson, Adam; Steiner, Ullrich; Federle, Walter

    2014-09-06

    Insect climbing footpads are able to adhere to rough surfaces, but the details of this capability are still unclear. To overcome experimental limitations of randomly rough, opaque surfaces, we fabricated transparent test substrates containing square arrays of 1.4 µm diameter pillars, with variable height (0.5 and 1.4 µm) and spacing (from 3 to 22 µm). Smooth pads of cockroaches (Nauphoeta cinerea) made partial contact (limited to the tops of the structures) for the two densest arrays of tall pillars, but full contact (touching the substrate in between pillars) for larger spacings. The transition from partial to full contact was accompanied by a sharp increase in shear forces. Tests on hairy pads of dock beetles (Gastrophysa viridula) showed that setae adhered between pillars for larger spacings, but pads were equally unable to make full contact on the densest arrays. The beetles' shear forces similarly decreased for denser arrays, but also for short pillars and with a more gradual transition. These observations can be explained by simple contact models derived for soft uniform materials (smooth pads) or thin flat plates (hairy-pad spatulae). Our results show that microstructured substrates are powerful tools to reveal adaptations of natural adhesives for rough surfaces.

  16. Evaluating the impact of direct and indirect contact on the mental health stigma of pharmacy students.

    PubMed

    Nguyen, Elizabeth; Chen, Timothy F; O'Reilly, Claire L

    2012-07-01

    Contact with mental health consumers has shown to be a promising strategy to address mental health stigma, particularly in the context of pharmacy education. This research aimed to compare the effectiveness of a direct (face-to-face) contact intervention with an indirect (film based) contact intervention in reducing the mental health stigma of pharmacy students. A two-group, non-randomized, comparative study was conducted with third year pharmacy students (n = 198) allocated to the direct contact arm and fourth year pharmacy students (n = 278) allocated to the indirect contact arm. Baseline and immediate post-intervention data were collected using a validated 39 item survey instrument to assess the impact of the interventions on mental health stigma as well as attitudes towards providing mental health pharmaceutical services. Participants in the direct contact group showed a significant improvement in 37 out of 39 survey items and participants in the indirect contact group showed a significant improvement in 27 out of 39 items (P < 0.05). While direct contact had a stronger impact than indirect contact for 22 items (P < 0.05), for numerous key measures of mental health stigma the impact of the two contact interventions was equivalent. Both indirect and direct contact may positively impact mental health stigma. While the strength of the stigma-change process may be heightened by face-to-face interactions, the largely positive impact of indirect contact suggests that stigma reduction may depend less on the medium of contact but more on the transcendent messages contributed by the consumers facilitating the contact experience.

  17. Gateway: Volume 3 Number 4

    DTIC Science & Technology

    1992-01-01

    applications are described, including windshield, symbols dancing trans- high- flight -time pilots (and big bud- an automobile system that permits driv...ORGANIZATION NAME(S) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBER Human Systems JAC 2261 Monahan Way, Bldg. 196 GWIII4 WPAFB OH> 45433-7022 9...release; distribution is unlimited. Free to public by contacting the Human Systems IAC. A 13. ABSTRACT (Maximum 200 Words) This issue contains articles

  18. 77 FR 25649 - Special Local Regulations for Marine Events; Patuxent River, Solomons, MD

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-01

    ..., an email address, or a telephone number in the body of your document so that we can contact you if we... Meeting We do not now plan to hold a public meeting. But you may submit a request for one, using one of..., please submit a comment (see ADDRESSES) explaining why you think it qualifies and how and to what degree...

  19. Literacy and Community. The Twentieth Yearbook: A Peer Reviewed Publication of the College Reading Association, 1998. [Papers from the College Reading Association Conference, 1997].

    ERIC Educational Resources Information Center

    Sturtevant, Elizabeth G., Ed.; Dugan, JoAnn, Ed.; Linder, Patricia, Ed.; Linek, Wayne M., Ed.

    This 20th Yearbook of the College Reading Association reflects the theme of "community" again and again, in diverse ways. First in the yearbook are the Presidential Address by Marino C. Alvarez, "Adolescent Literacy: Are We in Contact?" and the three Keynote Addresses: "My Life in Reading" (J. Chall); "A…

  20. 75 FR 36288 - Amended Safety Zone and Regulated Navigation Area, Chicago Sanitary and Ship Canal, Romeoville, IL

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-25

    ... current from the barriers would affect a human body if immersed in the water. The NEDU final report concluded that the possible effects to a human body if immersed in the water include paralysis of body... address, an e-mail address, or a telephone number in the body of your document so that we can contact you...

  1. The Contribution of Command and Control to Unity of Effort

    DTIC Science & Technology

    2002-09-01

    Engineering and Evaluation Centre University of South Australia Mawson Lakes, South Australia Author contact: 6 Frank Street St Morris SA 5068... Mawson Lakes, South Australia, , 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S...Noel Sproles PhD Systems Engineering and Evaluation Centre University of South Australia Mawson Lakes, South Australia While joint and multi-national

  2. 31 CFR 351.20 - What is the investment yield (interest) during the original maturity period of Series EE savings...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... email at [email protected], or by writing us at the following address: Bureau of the Public Debt... prior to 5 years from issue date at our website at www.savingsbonds.gov, by contacting us by email at [email protected], or writing to the following address: Bureau of the Public Debt, Parkersburg, West...

  3. Mahalanobis Distance-Based Classifiers are Able to Recognize EEG Patterns by Using Few EEG Electrodes

    DTIC Science & Technology

    2001-10-25

    Mouriño 3 , Angela Cattini 4 , Serenella Salinari 4 , Maria Grazia Marciani 2,5 and Febo Cincotti 5 1 Dip. Fisiologia umana e Farmacologia...Performing Organization Name(s) and Address(es) Dip. Fisiologia umana e Farmacologia, Università "La Sapienza", Rome, ITALY Performing Organization

  4. Civic-Mentoring Relationships: Implications for Student Development of Civic Mindedness

    ERIC Educational Resources Information Center

    Norris, Kristin E.

    2016-01-01

    Preparing students for responsible citizenship is important in higher education because we need graduates who are able to address the many issues in today's society (e.g., over-consumption of material goods, deeper political divides, fewer civic alliances, an inability to discuss public issues with civility and respect). In order to address these…

  5. Crystal structure of an SH2-kinase construct of c-Abl and effect of the SH2 domain on kinase activity

    PubMed Central

    Lorenz, Sonja; Deng, Patricia; Hantschel, Oliver; Superti-Furga, Giulio; Kuriyan, John

    2018-01-01

    Constitutive activation of the non-receptor tyrosine kinase c-Abl (Abl1) in the Bcr-Abl1 fusion oncoprotein is the molecular cause of chronic myeloid leukemia. Recent studies have indicated that an interaction between the SH2 domain and the N-lobe of the c-Abl kinase domain has a critical role in leukemogenesis. To dissect the structural basis of this phenomenon we studied c-Abl constructs comprising the SH2 and kinase domains in vitro. We present a crystal structure of an SH2-kinase domain construct bound to dasatinib, which contains the relevant interface between the SH2 domain and the N-lobe of the kinase domain. We show that the presence of the SH2 domain enhances kinase activity moderately and that this effect depends on contacts in the SH2-N-lobe interface and is abrogated by specific mutations. Consistently, formation of the interface decreases slightly the association rate of imatinib with the kinase domain. That the effects are small compared to the dramatic in vivo consequences suggests an important function of the SH2-N-lobe interaction might be to help disassemble the autoinhibited conformation of c-Abl and promote processive phosphorylation, rather than substantially stimulate kinase activity. PMID:25779001

  6. 78 FR 38020 - Agency Information Collection Extension

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-25

    ... before August 26, 2013. If you anticipate difficulty in submitting comments within that period, contact the person listed below as soon as possible. ADDRESSES: Written comments may be sent to Mark...

  7. 75 FR 5287 - Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-02

    ... above address; by e-mailing staffcfa.gov ; or by calling 202-504- 2200. Individuals requiring sign language interpretation for the hearing impaired should contact the Secretary at least 10 days before the...

  8. 78 FR 21603 - FIFRA Scientific Advisory Panel; Change of Meeting Dates

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-11

    ...., Arlington, VA 22202. FOR FURTHER INFORMATION CONTACT: Fred Jenkins, Designated Federal Official (DFO... address: jenkins[email protected] . SUPPLEMENTARY INFORMATION: All other information provided in the February...

  9. 77 FR 13248 - Texas: Final Authorization of State Hazardous Waste Management Program Revisions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-06

    ..., 2012. ADDRESSES: Send written comments to Alima Patterson, Region 6, Regional Authorization Coordinator... Federal Register. FOR FURTHER INFORMATION CONTACT: Alima Patterson (214) 665-8533. SUPPLEMENTARY...

  10. Streptomyces-Aspergillus flavus interactions: impact on aflatoxin B accumulation.

    PubMed

    Verheecke, C; Liboz, T; Anson, P; Zhu, Y; Mathieu, F

    2015-01-01

    The aim of this work was to investigate the potential of Streptomyces sp. as biocontrol agents against aflatoxins in maize. As such, we assumed that Streptomyces sp. could provide a complementary approach to current biocontrol systems such as Afla-guard(®) and we focused on biocontrol that was able to have an antagonistic contact with A. flavus. A previous study showed that 27 (out of 38) Streptomyces sp. had mutual antagonism in contact with A. flavus. Among these, 16 Streptomyces sp. were able to reduce aflatoxin content to below 17% of the residual concentration. We selected six strains to understand the mechanisms involved in the prevention of aflatoxin accumulation. Thus, in interaction with A. flavus, we monitored by RT-qPCR the gene expression of aflD, aflM, aflP, aflR and aflS. All the Streptomyces sp. were able to reduce aflatoxin concentration (24.0-0.2% residual aflatoxin B1). They all impacted on gene expression, but only S35 and S38 were able to repress expression significantly. Indeed, S35 significantly repressed aflM expression and S38 significantly repressed aflR, aflM and aflP. S6 reduced aflatoxin concentrations (2.3% residual aflatoxin B1) and repressed aflS, aflM and enhanced aflR expression. In addition, the S6 strain (previously identified as the most reducing pure aflatoxin B1) was further tested to determine a potential adsorption mechanism. We did not observe any adsorption phenomenon. In conclusion, this study showed that Streptomyces sp. prevent the production of (aflatoxin gene expression) and decontamination of (aflatoxin B1 reduction) aflatoxins in vitro.

  11. Contact freezing of supercooled cloud droplets on collision with mineral dust particles: effect of particle size

    NASA Astrophysics Data System (ADS)

    Hoffmann, Nadine; Duft, Denis; Kiselev, Alexei; Leisner, Thomas

    2013-04-01

    The contact freezing of supercooled cloud droplets is one of the potentially important and the least investigated heterogeneous mechanism of ice formation in the tropospheric clouds [1]. On the time scales of cloud lifetime the freezing of supercooled water droplets via contact mechanism may occur at higher temperature compared to the same IN immersed in the droplet. However, the laboratory experiments of contact freezing are very challenging due to the number of factors affecting the probability of ice formation. In our experiment we study single water droplets freely levitated in the laminar flow of mineral dust particles acting as the contact freezing nuclei. By repeating the freezing experiment sufficient number of times we are able to reproduce statistical freezing behavior of large ensembles of supercooled droplets and measure the average rate of freezing events. We show that the rate of freezing at given temperature is governed only by the rate of droplet -particle collision and by the properties of the contact ice nuclei. In this contribution we investigate the relationship between the freezing probability and the size of mineral dust particle (represented by illite) and show that their IN efficiency scales with the particle size. Based on this observation, we discuss the similarity between the freezing of supercooled water droplets in immersion and contact modes and possible mechanisms of apparent enhancement of the contact freezing efficiency. [1] - K.C. Young, The role of contact nucleation in ice phase initiation in clouds, Journal of the Atmospheric Sciences 31, 1974

  12. New Jersey (USA) wetlands past, present and future: using sediment archives to inform and guide wetland protection, restoration and resilience

    NASA Astrophysics Data System (ADS)

    Shaw, T.; Clear, J.; Horton, B.; Khan, N.; Nikitina, D.; Enache, M. D.; Potapova, M.; Frizzera, D.; Procopio, N.; Vane, C. H.; Walker, J. S.

    2016-12-01

    Due to the rapid and pervasive loss of coastal wetland ecosystems and the enumerable services they provide, recent attention has been given to understand their resilience and response to natural and anthropogenic impacts. Knowledge gaps exist particularly regarding response times of wetland ecosystems to natural factors (storms and sea-level rise) and the appropriate indices or metrics of ecosystem health to be incorporated in management practices to achieve restoration goals. Here we present results from monitoring studies and stratigraphic investigations from marshes across the New Jersey, USA shoreline from Delaware Bay to Raritan Bay (˜210 km of coastline that vary in degree of urbanization and anthropogenic disturbances) that address these limitations. In Delaware Bay, we identify a series of abrupt contacts (mud-peat couplets) from a sequence spanning the past two thousand years that we infer result from erosive storm events. By dating the base of these contacts and the return to high salt marsh peat, we are able to estimate the recovery time of marshes under varying rates of sea-level rise. In marshes from Great Sound to Raritan Bay, we use microfossils (e.g., foraminifera, diatoms) as indices of ecosystem health. We monitor the response of microfossils to natural (e.g., changes in salinity or inundation frequency from sea-level rise) and anthropogenic (e.g., nutrient loading) influences and apply quantitative paleoenvironmental reconstruction techniques to sediment archives to understand the relative influence of these factors on New Jersey wetlands over the past two thousand years. These results can be used to inform future coastal wetland restoration targets and as a model to develop site-specific goals in other regions.

  13. Staff experiences of an early warning indicator for unstable patients in Australia.

    PubMed

    Green, Anna; Williams, Allison; Allison, William

    2006-01-01

    The objective of this study is to explore nursing and medical staff's perceptions of a clinical marker referral tool implemented to assist in the early identification of unstable patients in the general surgical and medical ward environment. A descriptive, exploratory survey design was undertaken 6 months after the implementation of a clinical marker referral tool. The target population for the survey was all ward nursing, junior medical staff and intensive care unit (ICU) registrars in a metropolitan tertiary referral hospital in Australia. The survey consisted of open-ended and closed-ended questions, as well as statements asking participants to explore their perceptions, attitudes and perceived understanding of the clinical marker referral tool. The surveys were sent to all targeted staff in a personally addressed envelope via the internal mail system. Overall, nursing and medical staff (n = 178) responses were positive to the clinical marker project/tool, offering clear guidelines for staff to respond to the patient's clinical condition and contact the medical staff and the ICU liaison team as appropriate. Furthermore, comments were made in relation to the ICU liaison team acting as a 'support' and 'prompt back-up' for nursing staff when needed. However, ward medical staff had reservations with the clinical markers chosen and with ward nurses being able to contact the ICU registrar after hours. Additionally, the ICU registrars commented on an increase to their workload in having to review unstable patients after hours. These results suggest that the ward nurses required additional support and guidance in caring for the unstable patient in the ward which may improve patient outcomes. Further research investigating the less-favourable responses of the ward medical staff and ICU medical staff is warranted.

  14. Knowing so much, yet knowing so little: a scoping review of interventions that address the stigma of mental illness in the Canadian context.

    PubMed

    Guruge, Sepali; Wang, Arthur Ze Yu; Jayasuriya-Illesinghe, Vathsala; Sidani, Souraya

    2017-06-01

    Stigma can have detrimental effects on the health and wellbeing of individuals living with a mental illness. This scoping review describes the nature, range, and extent of intervention research aimed at reducing public and self-stigma of mental illness in the Canadian context. The review was guided by Arksey and O'Malley's framework. A search of databases and relevant websites identified 35 primary studies. Most studies used quantitative research methods and included predominantly youth or middle-aged adults, women, and white Canadian-born people. Guided by different conceptualizations of stigma, direct or indirect contact, education, and advocacy-focused interventions, aimed to provide information, and/or develop skills to address self and public stigma. Most studies evaluated interventions' effectiveness short-term. Of the few studies that followed-up participants long-term, some were able to reduce stigmatizing attitudes post-intervention, however, these targeted only specific groups such as students or health care professionals. Lack of diversity among the samples, and limited evidence of long-term effectiveness of interventions, were some of the studies' limitations. What is currently known about interventions aimed at reducing the stigma of mental illness in the Canadian context is not informed by research among vulnerable groups, such as people living with a mental illness, older adults, immigrants, and people of diverse ethnic backgrounds. Interventions that are informed by clear conceptualizations of stigma and rigorously evaluated in a range of ethno-cultural groups would create a knowledge base that is useful for policy-makers, community leaders, and agencies serving various ethnic communities in Canada.

  15. Prediction of protein long-range contacts using an ensemble of genetic algorithm classifiers with sequence profile centers.

    PubMed

    Chen, Peng; Li, Jinyan

    2010-05-17

    Prediction of long-range inter-residue contacts is an important topic in bioinformatics research. It is helpful for determining protein structures, understanding protein foldings, and therefore advancing the annotation of protein functions. In this paper, we propose a novel ensemble of genetic algorithm classifiers (GaCs) to address the long-range contact prediction problem. Our method is based on the key idea called sequence profile centers (SPCs). Each SPC is the average sequence profiles of residue pairs belonging to the same contact class or non-contact class. GaCs train on multiple but different pairs of long-range contact data (positive data) and long-range non-contact data (negative data). The negative data sets, having roughly the same sizes as the positive ones, are constructed by random sampling over the original imbalanced negative data. As a result, about 21.5% long-range contacts are correctly predicted. We also found that the ensemble of GaCs indeed makes an accuracy improvement by around 5.6% over the single GaC. Classifiers with the use of sequence profile centers may advance the long-range contact prediction. In line with this approach, key structural features in proteins would be determined with high efficiency and accuracy.

  16. Contact-aware simulations of particulate Stokesian suspensions

    NASA Astrophysics Data System (ADS)

    Lu, Libin; Rahimian, Abtin; Zorin, Denis

    2017-10-01

    We present an efficient, accurate, and robust method for simulation of dense suspensions of deformable and rigid particles immersed in Stokesian fluid in two dimensions. We use a well-established boundary integral formulation for the problem as the foundation of our approach. This type of formulation, with a high-order spatial discretization and an implicit and adaptive time discretization, have been shown to be able to handle complex interactions between particles with high accuracy. Yet, for dense suspensions, very small time-steps or expensive implicit solves as well as a large number of discretization points are required to avoid non-physical contact and intersections between particles, leading to infinite forces and numerical instability. Our method maintains the accuracy of previous methods at a significantly lower cost for dense suspensions. The key idea is to ensure interference-free configuration by introducing explicit contact constraints into the system. While such constraints are unnecessary in the formulation, in the discrete form of the problem, they make it possible to eliminate catastrophic loss of accuracy by preventing contact explicitly. Introducing contact constraints results in a significant increase in stable time-step size for explicit time-stepping, and a reduction in the number of points adequate for stability.

  17. 18 CFR 50.4 - Stakeholder participation.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ..., including a local or toll-free phone number, the name of a specific person to contact who is knowledgeable... pre-filing process, the Commission's Internet address, and the telephone number for the Commission's...

  18. 18 CFR 50.4 - Stakeholder participation.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., including a local or toll-free phone number, the name of a specific person to contact who is knowledgeable... pre-filing process, the Commission's Internet address, and the telephone number for the Commission's...

  19. 18 CFR 50.4 - Stakeholder participation.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., including a local or toll-free phone number, the name of a specific person to contact who is knowledgeable... pre-filing process, the Commission's Internet address, and the telephone number for the Commission's...

  20. 18 CFR 50.4 - Stakeholder participation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., including a local or toll-free phone number, the name of a specific person to contact who is knowledgeable... pre-filing process, the Commission's Internet address, and the telephone number for the Commission's...

  1. 18 CFR 50.4 - Stakeholder participation.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., including a local or toll-free phone number, the name of a specific person to contact who is knowledgeable... pre-filing process, the Commission's Internet address, and the telephone number for the Commission's...

  2. 78 FR 53436 - Agency Information Collection Extension

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-29

    ... anticipate difficulty in submitting comments within that period or if you want access to the collection of information, without charge, contact the person listed below as soon as possible. ADDRESSES: Written comments...

  3. 76 FR 14386 - Agency Information Collection Extension

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-16

    ... information collection must be received on or before May 16, 2011. If you anticipate difficulty in submitting comments within that period, contact the person listed below as soon as possible. ADDRESSES: Written...

  4. 19 CFR 207.11 - Contents of petition.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., phone number, and contact person(s) for each producer; (iii) A listing of all U.S. importers of the subject merchandise, including street addresses and phone numbers for each importer; (iv) Identification...

  5. 76 FR 8571 - Federal Property Suitable as Facilities To Assist the Homeless

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-14

    ... sanitary facilities, exact street address), providers should contact the appropriate landholding agencies... sanitary or heating facilities, Natl Register of Historic Places Bldg. 10 Property Number: 97199810002 VA...

  6. 47 CFR 0.121 - Location of field installations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... throughout the United States. For the address and phone number of the closest office contact the Enforcement... geographical coordinates (coordinates are referenced to North American Datum 1983 (NAD83)): Allegan, Michigan...

  7. 47 CFR 0.121 - Location of field installations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... throughout the United States. For the address and phone number of the closest office contact the Enforcement... geographical coordinates (coordinates are referenced to North American Datum 1983 (NAD83)): Allegan, Michigan...

  8. 75 FR 52319 - Environmental Management Site-Specific Advisory Board, Hanford

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-25

    .... ADDRESSES: Red Lion Hotel, 1415 5th Avenue, Seattle, WA 98101. FOR FURTHER INFORMATION CONTACT: Paula Call..., Safety and Environmental Protection Committee; Public Involvement Committee; and Budgets and Contracts...

  9. 78 FR 64211 - FIFRA Scientific Advisory Panel; Notice of Cancellation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-28

    ... August 9, 2013. The meeting will be rescheduled. FOR FURTHER INFORMATION CONTACT: Fred Jenkins, DFO... address: jenkins[email protected] . SUPPLEMENTARY INFORMATION: The meeting was announced in the Federal...

  10. Application of an industrial robot to nuclear pharmacy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Viola, J.

    1994-12-31

    Increased patient throughput and lengthened P.E.T. scan protocols have increased the radiation dose received by P.E.T. technologists. Automated methods of tracer infusion and blood sampling have been introduced to reduce direct contact with the radioisotopes, but significant radiation exposure still exists during the receipt and dispensing of the patient dose. To address this situation the authors have developed an automated robotic system which performs these tasks, thus limiting the physical contact between operator and radioisotope.

  11. Crepidula Slipper Limpets Alter Sex Change in Response to Physical Contact with Conspecifics.

    PubMed

    Carrillo-Baltodano, Allan; Collin, Rachel

    2015-12-01

    Chemical signaling, especially signaling with waterborne cues, is an important mode of communication between conspecifics of aquatic organisms. Although conspecific associations play an important role in sex allocation of sequential hermaphroditic slipper limpets, the mode of signaling is unknown. We tested the hypothesis that the effects of conspecifics on animal size and time of sex change in the tropical slipper limpet Crepidula cf. marginalis are mediated by waterborne cues. In our experiment, pairs of snails (one small and one large) were kept in cups, either together or partitioned off with fine or coarse mesh, or partitioned, but switched from side to side to allow contact with the cup mate's pedal mucus. The larger snails that were allowed contact with the smaller companions grew faster, and generally changed sex sooner, than did the larger snails in the barrier treatments, which allowed no physical contact. The smaller snails that were allowed contact with the larger cup mate delayed sex change compared to those separated from their cup mates. We were, therefore, able to reject the hypothesis that waterborne cues mediate communication between these snails. Our results suggest that the cue that affects size and time to sex change requires some kind of physical interaction that is lost when the snails are separated. Furthermore, contact with another snail's pedal mucus does not compensate for the loss of physical contact. Since males often attach to the shell of larger females, direct contact may mediate this kind of physical interaction via positional information, physical stimulation, or contact-based chemical communication. Whatever the cue, contact with conspecifics influences both partners, resulting in, surprisingly, a higher growth rate in the larger animal and delayed sex change in the smaller animal. © 2015 Marine Biological Laboratory.

  12. Fiber optics structural mechanics and nanotechnology based new generation of fiber coatings

    NASA Astrophysics Data System (ADS)

    Suhir, E.

    2006-02-01

    This paper consists of two parts - review and extension. The review part deals with typical fiber optics structures (bare, single- and dual-coated fibers; fibers experiencing low temperature micro-bending; fibers soldered into ferrules or adhesively bonded into capillaries; role of the non-linear stress-strain relationship, etc.) subjected to thermally induced and/or mechanical loading in bending, tension, compression, or to various combinations of such loadings. The emphasis is on the state-of-the-art in the area of optical fiber coatings and the functional (optical), mechanical and environmental problems that occur in polymer-coated or metallized fibers. The solutions to the examined problems are obtained using analytical methods (predictive models) of structural mechanics. The review is based primarily on the author's research conducted at Bell Laboratories, Murray Hill, NJ, during his eighteen years tenure with this company. The extension part addresses a new generation of optical fiber coatings and deals with the application of a newly developed (by the ERS/Siloptix Co.) nano-particle material (NPM) that is used as an attractive substitute for the existing optical fiber coatings. This NPM-based coating has all the merits of polymer and metal coatings, but is free of their shortcomings. The developed material is an unconventional inhomogeneous "smart" composite material, which is equivalent to a homogeneous material with the following major properties: low Young's modulus, immunity to corrosion, good-to-excellent adhesion to adjacent material(s), non-volatile, stable properties at temperature extremes (from -220°C to +350°C), very long (practically infinite) lifetime, "active" hydrophobicity - the material provides a moisture barrier (to both water and water vapor), and, if necessary, can even "wick" moisture away from the contact surface; ability for "self-healing" and "healing": the NPM is able to restore its own dimensions, when damaged, and is able to fill existing or developed defects (cracks and other "imperfections") in contacted surfaces; very low (near unity) effective refractive index (if needed). NPM can be designed, depending on the application, to enhance those properties most important. NPM properties have been confirmed through testing. The tests have demonstrated the outstanding mechanical reliability, extraordinary environmental durability and, in particular applications, improved optical performance of the light guide.

  13. Structural Mechanism of the Pan-BCR-ABL Inhibitor Ponatinib (AP24534): Lessons for Overcoming Kinase Inhibitor Resistance

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhou, Tianjun; Commodore, Lois; Huang, Wei-Sheng

    2012-01-20

    The BCR-ABL inhibitor imatinib has revolutionized the treatment of chronic myeloid leukemia. However, drug resistance caused by kinase domain mutations has necessitated the development of new mutation-resistant inhibitors, most recently against the T315I gatekeeper residue mutation. Ponatinib (AP24534) inhibits both native and mutant BCR-ABL, including T315I, acting as a pan-BCR-ABL inhibitor. Here, we undertook a combined crystallographic and structure-activity relationship analysis on ponatinib to understand this unique profile. While the ethynyl linker is a key inhibitor functionality that interacts with the gatekeeper, virtually all other components of ponatinib play an essential role in its T315I inhibitory activity. The extensive networkmore » of optimized molecular contacts found in the DFG-out binding mode leads to high potency and renders binding less susceptible to disruption by single point mutations. The inhibitory mechanism exemplified by ponatinib may have broad relevance to designing inhibitors against other kinases with mutated gatekeeper residues.« less

  14. Do corresponding authors take responsibility for their work? A covert survey.

    PubMed

    Teunis, Teun; Nota, Sjoerd P F T; Schwab, Joseph H

    2015-02-01

    Publication of a manuscript does not end an author's responsibilities. Reasons to contact an author after publication include clarification, access to raw data, and collaboration. However, legitimate questions have been raised regarding whether these responsibilities generally are being met by corresponding authors of biomedical publications. This study aims to establish (1) what proportion of corresponding authors accept the responsibility of correspondence; (2) identify characteristics of responders; and (3) assess email address decay with time. We hypothesize that the response rate is unrelated to journal impact factor. We contacted 450 corresponding authors throughout various fields of biomedical research regarding the availability of additional data from their study, under the pretense of needing these data for a related review article. Authors were randomly selected from 45 journals whose impact factors ranged from 52 to 0; the source articles were published between May 2003 and May 2013. The proportion of corresponding authors who replied, along with author characteristics were recorded, as was the proportion of emails that were returned for inactive addresses; 446 authors were available for final analysis. Fifty-three percent (190/357) of the authors with working email addresses responded to our request. Clinical researchers were more likely to reply than basic/translational scientists (51% [114/225] versus 34% [76/221]; p<0.001). Impact factor and other author characteristics did not differ. Logistic regression analysis showed that the odds of replying decreased by 15% per year (odds ratio [OR], 0.85; 95% CI, 0.79-0.91; p<0.001), and showed a positive relationship between clinical research and response (OR, 2.0; 95% CI, 1.3-2.9; p=0.001). In 2013 all email addresses (45/45) were reachable, but within 10 years, 49% (21/43) had become invalid. Our results suggest that contacting corresponding authors is problematic throughout the field of biomedical research. Defining the responsibilities of corresponding authors by journals more explicitly-particularly after publication of their manuscript-may increase the response rate on data requests. Possible other ways to improve communication after research publication are: (1) listing more than one email address per corresponding author, eg, an institutional and personal address; (2) specifying all authors' email addresses; (3) when an author leaves an institution, send an automated reply offering alternative ways to get in touch; and (4) linking published manuscripts to research platforms.

  15. Design, analysis, and applications of cellular contact-aided compliant mechanisms

    NASA Astrophysics Data System (ADS)

    Mehta, Vipul

    A new class of compliant mechanisms utilizing the benefits of cellular geometry and contact are addressed in this work. The design, analysis, fabrication and testing of such structures for high-strain and high-strength applications is the focus of the present research. Cellular structures have relatively good strength-to-weight ratios. They also have a higher strain capability than solid structures. Contact during deformation reduces failure-causing bending stresses through stress relief, thereby enabling such cellular structures to be stretched more than the corresponding structures without contact. Both analytical and numerical models are developed to represent one specific mechanism. Several candidate materials are investigated for such mechanisms. Although the allowable strain of all these materials is small, the overall strain of the contact-aided cellular mechanisms is at least an order of magnitude greater than that of the constitutive material. Application of contact to different materials yields an improvement in the global strain capacity by more than 100% relative to cellular structures without contact. Experiments are conducted to validate the models, and good agreement is found. Size optimization is carried out to maximize the stress relief and the overall strain. Two main applications are considered in the present work. One application consists of a morphing aircraft skin for adaptive structures. Different material models such as linearly elastic and multi-linear elastic are examined. For linearly elastic materials, contact-induced stress-relief is advantageous and for nonlinear elastic materials, reduction of transverse deflection due to contact is useful. The proposed contact-aided skin structure is compared with a cellular skin without contact. The contact mechanism helps to increase the morphing capacity while decreasing the structural mass. Using contact-aided cellular mechanisms, the global strain capability is increased by as much as 37%. For a fixed global strain, the optimum contact-aided structure is 15% lighter than an optimum non-contact structure. Another application involves investigation of meso-scaled cellular structures. Two different materials are considered---nanoparticulate zirconia and particulate stainless steel. The lost mold rapid infiltration forming process is utilized to fabricate free standing cellular mechanisms. The analytical model is employed to address the tradeoffs between the manufacturing constraints and to design suitable contact-aided cellular mechanisms. A custom rig is developed to test these meso-scaled parts. Force displacement characteristics are experimentally obtained and compared against those found using the analytical model. Topology optimization tools are applied to the design of compliant cellular mechanisms with and without a contact mechanism. A two-step procedure is developed. For cellular structures without contact, an inverse homogenization method is employed. The compliant mechanism is optimized to yield prescribed elasticity coefficients and achieve a large effective elastic strain. To implement a contact mechanism in the second step, the continuum model of a non-contact structure is converted into a frame model. Only the non-overlapping designs are investigated exhaustively for stress relief. A differential evolution optimizer is used to maximize the stress relief. Four cell topologies are found for different effective properties corresponding to different structural requirements. For each such topology, a contact mechanism is devised that demonstrates stress relief. One such topology resulted a stress relief as high as 36%.

  16. 10 CFR 1009.6 - Dissemination of prices and charges.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... the appropriate contact office should be addressed to the Office, of Finance and Accounting, Product Accounting and Pricing Branch, Mail Station 4A-139, 1000 Independence Avenue, SW., Washington, DC 20585. ...

  17. NOAA Freedom of Information Act (FOIA)

    Science.gov Websites

    Oceanic and Atmospheric Administration Office Freedom of Information Act (FOIA) HOME CoNtact Search Administration. Address your appeal to the following office: Assistant General Counsel for Administration (Office

  18. Head Lice: Information for Parents

    MedlinePlus

    ... Address What's this? Submit What's this? Submit Button Information For: Parents Schools Listen to audio/Podcast Related ... General Public. Contact Us Parasites Home Head Lice Information for Parents Language: English (US) Español (Spanish) Recommend ...

  19. 77 FR 26749 - Agency Information Collection Extension

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-07

    ... difficulty in submitting comments within that period, contact the person listed below as soon as possible. ADDRESSES: Written comments may be sent to: Eva Auman, GC-63, Department of Energy, 1000 Independence Ave...

  20. 76 FR 19985 - Agency Information Collection Extension

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-11

    ... anticipate difficulty in submitting comments within that period, contact the person listed below as soon as possible. ADDRESSES: Written comments may be sent to Richard Langston, U.S. Department of Energy, MA-61...

  1. 75 FR 36466 - Agency Information Collection Activity Seeking OMB Approval

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-25

    ... Noise. DATES: Please submit comments by July 26, 2010. FOR FURTHER INFORMATION CONTACT: Carla Scott at.... part A, Air Commerce Safety, and part B, Airport Development and Noise. Addresses: Interested persons...

  2. 76 FR 48148 - Environmental Management Site-Specific Advisory Board, Hanford

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-08

    .... ADDRESSES: Red Lion Hotel, 1415 5th Avenue, Seattle, WA 98101. FOR FURTHER INFORMATION CONTACT: Paula Call... Protection Committee; Public Involvement Committee; and Budgets and Contracts Committee. Life-Cycle Scope...

  3. 77 FR 27799 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-11

    .... ADDRESSES: Send comments to Nora Kincaid, BLS Clearance Officer, Division of Management Systems, Bureau of... INFORMATION CONTACT: Nora Kincaid, BLS Clearance Officer, 202-691-7628 (this is not a toll free number). (See...

  4. 75 FR 82002 - Environmental Management Site-Specific Advisory Board, Paducah

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-29

    ... Register. DATES: Thursday, January 20, 2011, 6 p.m. ADDRESSES: Barkley Centre, 111 Memorial Drive, Paducah... disabilities or special needs. If you require special accommodations due to a disability, please contact...

  5. 76 FR 80355 - Environmental Management Site-Specific Advisory Board, Paducah

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-23

    ... Register. DATES: Thursday, January 19, 2012, 5:30 p.m. ADDRESSES: Barkley Centre, 111 Memorial Drive... disabilities or special needs. If you require special accommodations due to a disability, please contact...

  6. 76 FR 48148 - Environmental Management Site-Specific Advisory Board, Paducah

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-08

    ... Register. DATES: Thursday, August 25, 2011; 6 p.m. ADDRESSES: Barkley Centre, 111 Memorial Drive, Paducah... disabilities or special needs. If you require special accommodations due to a disability, please contact...

  7. 76 FR 38179 - General Services Administration Acquisition Regulation; Information Collection; GSAR Provision...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-29

    ... CONTACT: Mr. Michael Jackson, Procurement Analyst, Contract Policy Division, GSA, (202) 208-4949 or michaelo.jackson@gsa.gov . ADDRESSES: Submit comments identified by Information Collection 3090- 0197, GSAR...

  8. 78 FR 32223 - Oklahoma: Final Authorization of State Hazardous Waste Management Program Revisions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-29

    ..., 2013. ADDRESSES: Send written comments to Alima Patterson, Region 6, Regional Authorization Coordinator... the Rules section of this Federal Register. FOR FURTHER INFORMATION CONTACT: Alima Patterson (214) 665...

  9. 77 FR 38566 - Louisiana: Final Authorization of State Hazardous Waste Management Program Revisions

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-28

    ... comments by July 30, 2012. ADDRESSES: Send written comments to Alima Patterson, Region 6, Regional... CONTACT: Alima Patterson (214) 665-8533. SUPPLEMENTARY INFORMATION: For additional information, please see...

  10. Patterns of usage and preferences of users for tuberculosis-related text messages and voice calls in Uganda.

    PubMed

    Ggita, J M; Ojok, C; Meyer, A J; Farr, K; Shete, P B; Ochom, E; Turimumahoro, P; Babirye, D; Mark, D; Dowdy, D; Ackerman, S; Armstrong-Hough, M; Nalugwa, T; Ayakaka, I; Moore, D; Haberer, J E; Cattamanchi, A; Katamba, A; Davis, J L

    2018-05-01

    Little information exists about mobile phone usage or preferences for tuberculosis (TB) related health communications in Uganda. We surveyed household contacts of TB patients in urban Kampala, Uganda, and clinic patients in rural central Uganda. Questions addressed mobile phone access, usage, and preferences for TB-related communications. We collected qualitative data about messaging preferences. We enrolled 145 contacts and 203 clinic attendees. Most contacts (58%) and clinic attendees (75%) owned a mobile phone, while 42% of contacts and 10% of clinic attendees shared one; 94% of contacts and clinic attendees knew how to receive a short messaging service (SMS) message, but only 59% of contacts aged 45 years (vs. 96% of contacts aged <45 years, P = 0.0001) did so. All contacts and 99% of clinic attendees were willing and capable of receiving personal-health communications by SMS. Among contacts, 55% preferred detailed messages disclosing test results, while 45% preferred simple messages requesting a clinic visit to disclose results. Most urban household TB contacts and rural clinic attendees reported having access to a mobile phone and willingness to receive TB-related personal-health communications by voice call or SMS. However, frequent phone sharing and variable messaging abilities and preferences suggest a need to tailor the design and monitoring of mHealth interventions to target recipients.

  11. A sonification algorithm for developing the off-roads models for driving simulators

    NASA Astrophysics Data System (ADS)

    Chiroiu, Veturia; Brişan, Cornel; Dumitriu, Dan; Munteanu, Ligia

    2018-01-01

    In this paper, a sonification algorithm for developing the off-road models for driving simulators, is proposed. The aim of this algorithm is to overcome difficulties of heuristics identification which are best suited to a particular off-road profile built by measurements. The sonification algorithm is based on the stochastic polynomial chaos analysis suitable in solving equations with random input data. The fluctuations are generated by incomplete measurements leading to inhomogeneities of the cross-sectional curves of off-roads before and after deformation, the unstable contact between the tire and the road and the unreal distribution of contact and friction forces in the unknown contact domains. The approach is exercised on two particular problems and results compare favorably to existing analytical and numerical solutions. The sonification technique represents a useful multiscale analysis able to build a low-cost virtual reality environment with increased degrees of realism for driving simulators and higher user flexibility.

  12. Mechanical Properties of Hydrogel Beads

    NASA Astrophysics Data System (ADS)

    Criddle, Keely; Benns, Thomas; Shorts, Dan; Feitosa, Klebert

    2015-03-01

    Fragile solids made of dense disordered packing of bubbles, droplets and grains are able to withstand small stresses by virtue of system-wide force chains that lock the system into a jammed state. The nature of the jamming transition in such soft materials has been the subject of intense research, but despite much effort, a deep understanding remains elusive. In this experiment we study the mechanical properties of hydrogel beads to exploit them as force transducers in densely packed systems. The experiment consists of applying uniaxial planar compressions on the beads, and correlating the force to the bead's strain and contact area. The results show that while the strain scales linearly with the diameter of the contact area, the force and strain are found to obey a power law relation with two distinct exponents at small and large strains. This result leads to a power law dependence of the force on the contact area diameter of the compressed bead.

  13. First epidemiological study of contact dermatitis in Spain - 1977. Spanish Contact Dermatitis Research Group.

    PubMed

    Camarasa, J M

    1979-01-01

    The present work is the first epidemiological study carried out by the Spanish Contact Dermatitis Research Group during 1977. During this year 2806 patients were studied with patch test among 30873 dermatological patients. The 60-62% of the totality had reactivity to one or more patches. Four major groups of allergens were able to consider, following the incidence in their power of sensitize. First group with strong incidence include: Nickel, Chromate, Cobalt, T.M.T.D.,P.P.D.A., Mercapto mix., and Wood tars. Second and third groups with medium incidence contain: Caines, Carbonates, Neomycin, Balsam of Peru, Mercury, Lanolin, Naphtyl mix., Formaldehyde, Benzalkonium chloride, P. P. D. A. mix, and Turpentine. Four group show very low incidence substances, as: Epoxi, Sulfonamides, Etilendiamine, Parabens, Chinoform, Colophony and Cinnamon oil. Few comments about age and occupations are included.

  14. [Benzalkonium chloride: unacceptable to sterilize or disinfect medical or dental instruments].

    PubMed

    Acosta-Gío, E; Herrero-Farías, A; Mata-Portuguez, V H

    2001-01-01

    To compare the sporicidal activity of benzalkonium chloride (BKC) with that of glutaraldehyde. A comparative study was conducted at the microbiology laboratory of Facultad de Odontología, Universidad Nacional Autónoma de México. Bacillus subtilis ATCC 9372 spores were exposed to these germicides (1 spore x mL) on a 0.22 mm filter. After completing the contact time the spores were washed and the filters were incubated on nutrient agar for 72 h at 37 degrees C. BKC did not eliminate B. subtilis spores at the concentration used, not even after increasing contact time to 15 h (900-fold the recommended time). Two percent glutaraldehyde destroyed spores only after 10 h of contact. Urea and sodium chloride showed no sporicidal activity. The results confirm that BKC lacks sporicidal activity and confirm that this quaternary ammonium compound is not able to "sterilize" or "disinfect" medical and dental instruments.

  15. Dynamics of liquid spreading on solid surfaces

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kalliadasis, S.; Chang, H.C.

    1996-09-01

    Using simple scaling arguments and a precursor film model, the authors show that the appropriate macroscopic contact angle {theta} during the slow spreading of a completely or partially wetting liquid under conditions of viscous flow and small slopes should be described by tan {theta} = [tan{sup 3} {theta}{sub e} {minus} 9 log {eta}Ca]{sup 1/3} where {theta}{sub e} is the static contact angle, Ca is the capillary number, and {eta} is a scaled Hamaker constant. Using this simple relation as a boundary condition, the authors are able to quantitatively model, without any empirical parameter, the spreading dynamics of several classical spreadingmore » phenomena (capillary rise, sessile, and pendant drop spreading) by simply equating the slope of the leading order static bulk region to the dynamic contact angle boundary condition without performing a matched asymptotic analysis for each case independently as is usually done in the literature.« less

  16. Points of Contact for Oceanographic Institutes in Europe and Russia

    DTIC Science & Technology

    1993-05-20

    Wolfgang dle Initial: t Name: Fennel Title: Dr. 40ompany: Institut fur Ostseeforschung Address 1: Warnemunde an der Universitat Rostock Address 2...Phone: Cellular: Category: physics Notes: fennel~physik iowarnemuende.dbp.de, Telex: 398516 do d Wolfgang Fijnaut Royal Netherlands Meteorological...34Phone: Fax: Home Phone: Cellular: Category: administration Notes: Head Krause AifredWegenerinstitut fur Polar u4p M_.peresforechun +49 (0) 471 4831 0

  17. 78 FR 35663 - Endangered and Threatened Wildlife and Plants; Removing the Gray Wolf (Canis lupus) From the List...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-13

    .... Kempthorne, 579 F. Supp. 2d 7 (D.D.C. 2008)) and, in one case, a settlement agreement (Humane Society of the... INFORMATION CONTACT by July 29, 2013. ADDRESSES: You may submit comments by one of the following methods: (1.... You may submit your comments and materials by one of the methods listed in ADDRESSES. We will not...

  18. The Asia-Pacific: A Region in Transition

    DTIC Science & Technology

    2004-01-01

    NAME(S) AND ADDRESS(ES) Asia-Pacific Center for Security Studies ,2058 Maluhia Road ,Honolulu,HI,96815 8. PERFORMING ORGANIZATION REPORT NUMBER 9...Center for Security Studies Reprint permission: Contact the editors at 2058 Maluhia Road, Honolulu, HI 96815 All views expressed in the chapters of...this book are those of the authors and do not necessarily reflect the views of the Asia-Pacific Center for Security Studies (APCSS) or any

  19. Data Reliability Assessment Review of win.Compare2 Software

    DTIC Science & Technology

    2001-05-23

    Task Number Work Unit Number Performing Organization Name(s) and Address(es) OAIG-AUD (ATTN: AFTS Audit Suggestions) Inspector General Department...distribution unlimited Supplementary Notes Abstract The audit was requested on June 23, 2000, by the Director, Competitive Sourcing and Privatization...To obtain additional copies of this audit report, visit the Inspector General, DoD Home Page at www.dodig.osd.mil/ audit /reports or contact the

  20. Conceptualizing patient empowerment in cancer follow-up by combining theory and qualitative data.

    PubMed

    Johnsen, Anna Thit; Eskildsen, Nanna Bjerg; Thomsen, Thora Grothe; Grønvold, Mogens; Ross, Lone; Jørgensen, Clara R

    2017-02-01

    Patient empowerment (PE) may be defined as the opportunity for patients to master issues important to their own health. The aim of this study was to conceptualize PE and how the concept manifests itself for cancer patients attending follow-up, in order to develop a relevant and sensitive questionnaire for this population. A theoretical model of PE was made, based on Zimmerman's theory of psychological empowerment. Patients who were in follow-up after first line treatment for their cancer (n = 16) were interviewed about their experiences with follow-up. A deductive thematic analysis was conducted to contextualize the theory and find concrete manifestations of empowerment. Data were analyzed to find situations that expressed empowerment or lack of empowerment. We then analyzed what abilities these situations called for and we further analyzed how these abilities fitted Zimmerman's theory. In all, 16 patients from two different hospitals participated in the interviews. PE in cancer follow-up was conceptualized as: (1) the perception that one had the possibility of mastering treatment and care (e.g. the possibility of 'saying no' to treatment and getting in contact with health care when needed); (2) having knowledge and skills regarding, for example treatment, care, plan of treatment and care, normal reactions and late effects, although knowledge and information was not always considered positively; and (3) being able to make the health care system address one's concerns and needs and, for some patients, also being able to monitor one's treatment, tests and care. We conceptualized PE based on Zimmerman's theory and empirical data to contextualize the concept in cancer follow-up. When developing a patient reported outcome measure measuring PE for this group of patients, one needs to be attentive to differences in wishes regarding mastery.

  1. Electrostatic Studies for the 2008 Hubble Service Repair Mission

    NASA Technical Reports Server (NTRS)

    Buhler, C. R.; Clements, J. S.; Calle, C. I.

    2012-01-01

    High vacuum triboelectric testing of space materials was required to identify possible Electrostatic Discharge (ESD) concerns for the astronauts in space during electronics board replacement on the Hubble Space Telescope. Testing under high vacuum conditions with common materials resulted in some interesting results. Many materials were able to charge to high levels which did not dissipate quickly even when grounded. Certain materials were able to charge up in contact with grounded metals while others were not. An interesting result was that like materials did not exchange electrostatic charge under high vacuum conditions. The most surprising experimental result is the lack of brush discharges from charged insulators under high vacuum conditions.

  2. Addressing Physical and Emotional Issues in Children's Literature

    ERIC Educational Resources Information Center

    Johnson, Jonathon

    2010-01-01

    The purpose of this paper is to examine how physical and mental disabilities are addressed in children's literature. Many authors are able to integrate the issues into their work in a way that enhances the story and benefits the reader. As young readers learn about the issues and struggles faced by children with mental and physical disabilities,…

  3. Participant Recruitment through Social Media: Lessons Learned from a Qualitative Radicalization Study Using Facebook

    ERIC Educational Resources Information Center

    Sikkens, Elga; van San, Marion; Sieckelinck, Stijn; Boeije, Hennie; de Winter, Micha

    2017-01-01

    Social media are useful facilitators when recruiting hidden populations for research. In our research on youth and radicalization, we were able to find and contact young people with extreme ideals through Facebook. In this article, we discuss our experiences using Facebook as a tool for finding respondents who do not trust researchers. Facebook…

  4. 76 FR 11240 - Human Studies Review Board (HSRB); Notification of a Public Teleconference To Review a Draft...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-01

    ... subjects of research. The HSRB reports to the EPA Administrator through EPA's Science Advisor. 1. Topics...) Office of the Science Advisor (OSA) announces a public teleconference of the HSRB to discuss its draft... difficulties and cannot contact you for clarification, EPA may not be able to consider your comment. Electronic...

  5. 77 FR 51798 - First Draft Documents Related to the Review of the National Ambient Air Quality Standards for Ozone

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-27

    ... comment due to technical difficulties and cannot contact you for clarification, EPA may not be able to... comments, remember to: Identify the rulemaking by docket number and other identifying information (subject... 2009 and was the subject of a consultation with the Clean Air Scientific Advisory Committee (CASAC) on...

  6. 75 FR 11877 - Review of the Secondary National Ambient Air Quality Standards for Oxides of Nitrogen and Oxides...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-12

    ... difficulties and cannot contact you for clarification, EPA may not be able to consider your comment. Electronic... rulemaking by docket number and other identifying information (subject heading, Federal Register date and... assess the science, risks, and policies relevant to protecting the public welfare associated with NO X...

  7. 78 FR 2394 - Release of Draft Document Related to the Review of the National Ambient Air Quality Standards for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-11

    ... technical difficulties and cannot contact you for clarification, the EPA may not be able to consider your... docket number and other identifying information (subject heading, Federal Register date and page number... information presented in the third draft Integrated Science Assessment for Lead \\2\\ and health and ecological...

  8. 75 FR 44246 - Petition For Rulemaking to Establish Procedures For The Creation and Amendment of Endangered...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-28

    ... availability of a January 19, 2010 petition from Dow AgroSciences LLC (``DAS''), Makhteshim Agan of North... comment due to technical difficulties and cannot contact you for clarification, EPA may not be able to... (subject heading, Federal Register date and page number). ii. Follow directions. The Agency may ask you to...

  9. 78 FR 63136 - Drawbridge Operation Regulation; Inner Harbor Navigational Canal, New Orleans, LA

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-23

    ... operating schedules so the bridge owner would be able to use the same bridge crew personnel to operate both bridges with little to no effect on navigation through the bridges. DATES: Comments and related material... INFORMATION CONTACT: If you have questions on this proposed rule, call or email the Coast Guard; Mr. Jim...

  10. 76 FR 30425 - Receipt of Petition for Decision That Nonconforming 2007-2011 Suzuki GSX1300R Motorcycles Are...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-25

    ...-mounted reflex reflector; (d) rear turn signal lamps; (e) stoplamp; (f) taillamp; and (g) license plate... provided. Please see the Privacy Act heading below. Privacy Act: Anyone is able to search the electronic... that you periodically search the Docket for new material. FOR FURTHER INFORMATION CONTACT: Coleman...

  11. 76 FR 14116 - Notice of Receipt of Petition for Decision That Nonconforming 2002 Kawasaki Ninja ZX-6R...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-15

    ... assembly (including stoplamp, taillamp, and license plate lamp); and (e) front and rear turn signal lamps... Privacy Act heading below. Privacy Act: Anyone is able to search the electronic form of all comments... recommend that you periodically search the Docket for new material. FOR FURTHER INFORMATION CONTACT: Coleman...

  12. 76 FR 1359 - Drawbridge Operation Regulation; Atlantic Intracoastal Waterway, Wrightsville Beach, NC

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-10

    ... the deviation in the past three years. The bridge will not be able to open for emergencies. In... INFORMATION CONTACT: If you have questions on this rule, call or e-mail Lindsey Middleton, Coast Guard; telephone 757-398-6629, e-mail [email protected] . If you have questions on viewing the docket...

  13. 78 FR 70088 - Agency Proposed Business Process Vision Under the Rehabilitation Act of 1973

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-22

    ... Church, Virginia, where the public could provide us with comments in person or via telephone. The notice... tracking number to confirm your submission. You will not be able to view your comment immediately as we...://www.regulations.gov , or in person, during regular business hours, by arranging with the contact...

  14. Enhancing Your Web Site as a Recruitment Tool by Implementing Chat Technology

    ERIC Educational Resources Information Center

    Benjamin, Blair; Lee, Jay

    2005-01-01

    By nearly all accounts, the Web has overwhelmingly become the primary resource for prospective students to research potential college choices. Using this medium, however, prospects are able to do their research independently and privately, without having to contact the institution via phone, mail or email to make a formal inquiry. Consequently,…

  15. 77 FR 43135 - Application of City Wings, Inc. D/B/A Seaflight for Commuter Authority

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-23

    ... DEPARTMENT OF TRANSPORTATION [Docket DOT-OST-2010-0263] Application of City Wings, Inc. D/B/A... cause why it should not issue an order finding City Wings, Inc. d/b/a Seaflight fit, willing, and able... be served upon the parties listed in Attachment A to the order. FOR FURTHER INFORMATION CONTACT...

  16. The Structure of Informal Social Networks of Persons with Profound Intellectual and Multiple Disabilities

    ERIC Educational Resources Information Center

    Kamstra, A.; van der Putten, A. A. J.; Vlaskamp, C.

    2015-01-01

    Background: Persons with less severe disabilities are able to express their needs and show initiatives in social contacts, persons with profound intellectual and multiple disabilities (PIMD), however, depend on others for this. This study analysed the structure of informal networks of persons with PIMD. Materials and Methods: Data concerning the…

  17. 21 CFR 111.35 - Under this subpart D, what records must you make and keep?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., and any other contact surfaces that are used to manufacture, package, label, or hold components or... current software is not able to retrieve such records) and of data entered into computer systems that you use to manufacture, package, label, or hold dietary supplements. (i) Your backup file (e.g., a hard...

  18. 21 CFR 111.35 - Under this subpart D, what records must you make and keep?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., and any other contact surfaces that are used to manufacture, package, label, or hold components or... current software is not able to retrieve such records) and of data entered into computer systems that you use to manufacture, package, label, or hold dietary supplements. (i) Your backup file (e.g., a hard...

  19. 21 CFR 111.35 - Under this subpart D, what records must you make and keep?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., and any other contact surfaces that are used to manufacture, package, label, or hold components or... current software is not able to retrieve such records) and of data entered into computer systems that you use to manufacture, package, label, or hold dietary supplements. (i) Your backup file (e.g., a hard...

  20. Usage of insecure E-mail services among researchers with different scientific background.

    PubMed

    Solić, Kresimir; Grgić, Krešimir; Ilakovac, Vesna; Zagar, Drago

    2011-08-01

    Free web‑based e-mail services are considered to have more security flaws than institutional ones, but they are frequently used among scientific researchers for professional communication. The aim of this study was to analyze frequency of usage of the insecure free e-mail services for professional communication among biomedical, economical and technical researchers, who published papers in one of three different journals: Croatian Medical Journal, Automatika and Economic Research. Contact details of the authors who provided their e‑mail address from the papers published in those three journals during one year period were collected. These e‑mail addresses were collected from the electronic archive of the journals in question. The domains of all e‑mail addresses were assessed and contacts were categorized into three groups according to the following types: world-wide known free web‑based e‑mail services, national Internet Service Provider (ISP) e-mail services, and institutional or corporate e-mail addresses. The proportion of authors using free web-based e-mail services, the least secure group type, was highest among biomedical researchers (17.8%) while every e‑mail address collected from the technical journal belonged to the secured institutional e‑mail group type. It seems that all researchers from the technical scientific field and most of the researchers from the economical field value good security practice and use more secure systems for professional communication. High percentage of the biomedical researchers who use insecure e‑mail services may mean that they need to be warned of the possible security disadvantages of those kinds of e‑mail addresses.

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