Science.gov

Sample records for absolute standard deviation

  1. Set standard deviation, repeatability and offset of absolute gravimeter A10-008

    USGS Publications Warehouse

    Schmerge, D.; Francis, O.

    2006-01-01

    The set standard deviation, repeatability and offset of absolute gravimeter A10-008 were assessed at the Walferdange Underground Laboratory for Geodynamics (WULG) in Luxembourg. Analysis of the data indicates that the instrument performed within the specifications of the manufacturer. For A10-008, the average set standard deviation was (1.6 0.6) ??Gal (1Gal ??? 1 cm s -2), the average repeatability was (2.9 1.5) ??Gal, and the average offset compared to absolute gravimeter FG5-216 was (3.2 3.5) ??Gal. ?? 2006 BIPM and IOP Publishing Ltd.

  2. Introducing the Mean Absolute Deviation "Effect" Size

    ERIC Educational Resources Information Center

    Gorard, Stephen

    2015-01-01

    This paper revisits the use of effect sizes in the analysis of experimental and similar results, and reminds readers of the relative advantages of the mean absolute deviation as a measure of variation, as opposed to the more complex standard deviation. The mean absolute deviation is easier to use and understand, and more tolerant of extreme…

  3. Reducing the Standard Deviation in Multiple-Assay Experiments Where the Variation Matters but the Absolute Value Does Not

    PubMed Central

    Echenique-Robba, Pablo; Nelo-Bazán, María Alejandra; Carrodeguas, José A.

    2013-01-01

    When the value of a quantity for a number of systems (cells, molecules, people, chunks of metal, DNA vectors, so on) is measured and the aim is to replicate the whole set again for different trials or assays, despite the efforts for a near-equal design, scientists might often obtain quite different measurements. As a consequence, some systems’ averages present standard deviations that are too large to render statistically significant results. This work presents a novel correction method of a very low mathematical and numerical complexity that can reduce the standard deviation of such results and increase their statistical significance. Two conditions are to be met: the inter-system variations of matter while its absolute value does not, and a similar tendency in the values of must be present in the different assays (or in other words, the results corresponding to different assays must present a high linear correlation). We demonstrate the improvements this method offers with a cell biology experiment, but it can definitely be applied to any problem that conforms to the described structure and requirements and in any quantitative scientific field that deals with data subject to uncertainty. PMID:24205158

  4. Constrained Least Absolute Deviation Neural Networks

    PubMed Central

    Wang, Zhishun; Peterson, Bradley S.

    2008-01-01

    It is well known that least absolute deviation (LAD) criterion or L1-norm used for estimation of parameters is characterized by robustness, i.e., the estimated parameters are totally resistant (insensitive) to large changes in the sampled data. This is an extremely useful feature, especially, when the sampled data are known to be contaminated by occasionally occurring outliers or by spiky noise. In our previous works, we have proposed the least absolute deviation neural network (LADNN) to solve unconstrained LAD problems. The theoretical proofs and numerical simulations have shown that the LADNN is Lyapunov-stable and it can globally converge to the exact solution to a given unconstrained LAD problem. We have also demonstrated its excellent application value in time-delay estimation. More generally, a practical LAD application problem may contain some linear constraints, such as a set of equalities and/or inequalities, which is called constrained LAD problem, whereas the unconstrained LAD can be considered as a special form of the constrained LAD. In this paper, we present a new neural network called constrained least absolute deviation neural network (CLADNN) to solve general constrained LAD problems. Theoretical proofs and numerical simulations demonstrate that the proposed CLADNN is Lyapunov stable and globally converges to the exact solution to a given constrained LAD problem, independent of initial values. The numerical simulations have also illustrated that the proposed CLADNN can be used to robustly estimate parameters for nonlinear curve fitting, which is extensively used in signal and image processing. PMID:18269958

  5. The Standard Deviation of Launch Vehicle Environments

    NASA Technical Reports Server (NTRS)

    Yunis, Isam

    2005-01-01

    Statistical analysis is used in the development of the launch vehicle environments of acoustics, vibrations, and shock. The standard deviation of these environments is critical to accurate statistical extrema. However, often very little data exists to define the standard deviation and it is better to use a typical standard deviation than one derived from a few measurements. This paper uses Space Shuttle and expendable launch vehicle flight data to define a typical standard deviation for acoustics and vibrations. The results suggest that 3dB is a conservative and reasonable standard deviation for the source environment and the payload environment.

  6. Weighted Wilcoxon-type Smoothly Clipped Absolute Deviation Method

    PubMed Central

    Wang, Lan; Li, Runze

    2009-01-01

    Summary Shrinkage-type variable selection procedures have recently seen increasing applications in biomedical research. However, their performance can be adversely influenced by outliers in either the response or the covariate space. This paper proposes a weighted Wilcoxon-type smoothly clipped absolute deviation (WW-SCAD) method, which deals with robust variable selection and robust estimation simultaneously. The new procedure can be conveniently implemented with the statistical software R. We establish that the WW-SCAD correctly identifies the set of zero coefficients with probability approaching one and estimates the nonzero coefficients with the rate n−1/2. Moreover, with appropriately chosen weights the WW-SCAD is robust with respect to outliers in both the x and y directions. The important special case with constant weights yields an oracle-type estimator with high efficiency at the presence of heavier-tailed random errors. The robustness of the WW-SCAD is partly justified by its asymptotic performance under local shrinking contamination. We propose a BIC-type tuning parameter selector for the WW-SCAD. The performance of the WW-SCAD is demonstrated via simulations and by an application to a study that investigates the effects of personal characteristics and dietary factors on plasma beta-carotene level. PMID:18647294

  7. Absolute Standards for Climate Measurements

    NASA Astrophysics Data System (ADS)

    Leckey, J.

    2016-10-01

    In a world of changing climate, political uncertainty, and ever-changing budgets, the benefit of measurements traceable to SI standards increases by the day. To truly resolve climate change trends on a decadal time scale, on-orbit measurements need to be referenced to something that is both absolute and unchanging. One such mission is the Climate Absolute Radiance and Refractivity Observatory (CLARREO) that will measure a variety of climate variables with an unprecedented accuracy to definitively quantify climate change. In the CLARREO mission, we will utilize phase change cells in which a material is melted to calibrate the temperature of a blackbody that can then be observed by a spectrometer. A material's melting point is an unchanging physical constant that, through a series of transfers, can ultimately calibrate a spectrometer on an absolute scale. CLARREO consists of two primary instruments: an infrared (IR) spectrometer and a reflected solar (RS) spectrometer. The mission will contain orbiting radiometers with sufficient accuracy to calibrate other space-based instrumentation and thus transferring the absolute traceability. The status of various mission options will be presented.

  8. A Note on Standard Deviation and Standard Error

    ERIC Educational Resources Information Center

    Hassani, Hossein; Ghodsi, Mansoureh; Howell, Gareth

    2010-01-01

    Many students confuse the standard deviation and standard error of the mean and are unsure which, if either, to use in presenting data. In this article, we endeavour to address these questions and cover some related ambiguities about these quantities.

  9. Application of Mean of Absolute Deviation Method for the Selection of Best Nonlinear Component Based on Video Encryption

    NASA Astrophysics Data System (ADS)

    Anees, Amir; Khan, Waqar Ahmad; Gondal, Muhammad Asif; Hussain, Iqtadar

    2013-07-01

    The aim of this work is to make use of the mean of absolute deviation (MAD) method for the evaluation process of substitution boxes used in the advanced encryption standard. In this paper, we use the MAD technique to analyze some popular and prevailing substitution boxes used in encryption processes. In particular, MAD is applied to advanced encryption standard (AES), affine power affine (APA), Gray, Lui J., Residue Prime, S8 AES, SKIPJACK, and Xyi substitution boxes.

  10. Does standard deviation matter? Using "standard deviation" to quantify security of multistage testing.

    PubMed

    Wang, Chun; Zheng, Yi; Chang, Hua-Hua

    2014-01-01

    With the advent of web-based technology, online testing is becoming a mainstream mode in large-scale educational assessments. Most online tests are administered continuously in a testing window, which may post test security problems because examinees who take the test earlier may share information with those who take the test later. Researchers have proposed various statistical indices to assess the test security, and one most often used index is the average test-overlap rate, which was further generalized to the item pooling index (Chang & Zhang, 2002, 2003). These indices, however, are all defined as the means (that is, the expected proportion of common items among examinees) and they were originally proposed for computerized adaptive testing (CAT). Recently, multistage testing (MST) has become a popular alternative to CAT. The unique features of MST make it important to report not only the mean, but also the standard deviation (SD) of test overlap rate, as we advocate in this paper. The standard deviation of test overlap rate adds important information to the test security profile, because for the same mean, a large SD reflects that certain groups of examinees share more common items than other groups. In this study, we analytically derived the lower bounds of the SD under MST, with the results under CAT as a benchmark. It is shown that when the mean overlap rate is the same between MST and CAT, the SD of test overlap tends to be larger in MST. A simulation study was conducted to provide empirical evidence. We also compared the security of MST under the single-pool versus the multiple-pool designs; both analytical and simulation studies show that the non-overlapping multiple-pool design will slightly increase the security risk.

  11. Standardization of the cumulative absolute velocity

    SciTech Connect

    O'Hara, T.F.; Jacobson, J.P. )

    1991-12-01

    EPRI NP-5930, A Criterion for Determining Exceedance of the Operating Basis Earthquake,'' was published in July 1988. As defined in that report, the Operating Basis Earthquake (OBE) is exceeded when both a response spectrum parameter and a second damage parameter, referred to as the Cumulative Absolute Velocity (CAV), are exceeded. In the review process of the above report, it was noted that the calculation of CAV could be confounded by time history records of long duration containing low (nondamaging) acceleration. Therefore, it is necessary to standardize the method of calculating CAV to account for record length. This standardized methodology allows consistent comparisons between future CAV calculations and the adjusted CAV threshold value based upon applying the standardized methodology to the data set presented in EPRI NP-5930. The recommended method to standardize the CAV calculation is to window its calculation on a second-by-second basis for a given time history. If the absolute acceleration exceeds 0.025g at any time during each one second interval, the earthquake records used in EPRI NP-5930 have been reanalyzed and the adjusted threshold of damage for CAV was found to be 0.16g-set.

  12. Comparison of estimators of standard deviation for hydrologic time series.

    USGS Publications Warehouse

    Tasker, Gary D.; Gilroy, E.J.

    1982-01-01

    Unbiasing factors as a function of serial correlation, rho, and sample size, n for the sample standard deviation of a lag one autoregressive model were generated by random number simulation. Monte Carlo experiments were used to compare the performance of several alternative methods for estimating the standard deviation sigma of a lag one autoregressive model in terms of bias, root mean square error, probability of underestimation, and expected opportunity design loss. -from Authors

  13. Quantitative standards for absolute linguistic universals.

    PubMed

    Piantadosi, Steven T; Gibson, Edward

    2014-01-01

    Absolute linguistic universals are often justified by cross-linguistic analysis: If all observed languages exhibit a property, the property is taken to be a likely universal, perhaps specified in the cognitive or linguistic systems of language learners and users. In many cases, these patterns are then taken to motivate linguistic theory. Here, we show that cross-linguistic analysis will very rarely be able to statistically justify absolute, inviolable patterns in language. We formalize two statistical methods--frequentist and Bayesian--and show that in both it is possible to find strict linguistic universals, but that the numbers of independent languages necessary to do so is generally unachievable. This suggests that methods other than typological statistics are necessary to establish absolute properties of human language, and thus that many of the purported universals in linguistics have not received sufficient empirical justification.

  14. A Method for Selecting between Fisher's Linear Classification Functions and Least Absolute Deviation in Predictive Discriminant Analysis.

    ERIC Educational Resources Information Center

    Meshbane, Alice; Morris, John D.

    A method for comparing the cross-validated classification accuracy of Fisher's linear classification functions (FLCFs) and the least absolute deviation is presented under varying data conditions for the two-group classification problem. With this method, separate-group as well as total-sample proportions of current classifications can be compared…

  15. Absolute calibration of 10Be AMS standards

    NASA Astrophysics Data System (ADS)

    Nishiizumi, Kunihiko; Imamura, Mineo; Caffee, Marc W.; Southon, John R.; Finkel, Robert C.; McAninch, Jeffrey

    2007-05-01

    The increased detection sensitivity offered by AMS has dramatically expanded the utility of 10Be. As these applications become more sophisticated attention has focused on the accuracy of the 10Be standards used to calibrate the AMS measurements. In recent years it has become apparent that there is a discrepancy between two of the most widely used 10Be AMS standards, the ICN 10Be standard and the NIST 10Be standard. The ICN (ICN Chemical & Radioisotope Division) 10Be AMS standard was calibrated by radioactive decay counting. Dilutions, ranging from 5 × 10 -13 to 3 × 10 -1110Be/Be, have been prepared and are extensively used in many AMS laboratories. The NIST 10Be standard, prepared at the National Institute of Standards and Technology (NIST), is calibrated by mass spectrometric isotope ratio measurements. To provide an independent calibration of the 10Be standards we implanted a known number of 10Be atoms in both Si detectors and Be foil targets. The 10Be concentrations in these targets were measured by AMS. The results were compared with both the ICN and NIST AMS standards. Our 10Be measurements indicate that the 10Be/ 9Be isotopic ratio of the ICN AMS standard, which is based on a 10Be half-life of 1.5 × 10 6 yr, is 1.106 ± 0.012 times lower than the nominal value. Since the decay rate of the ICN standard is well determined, the decrease in 10Be/ 9Be ratio requires that the 10Be half-life be reduced to (1.36 ± 0.07) × 10 6 yr. The quoted uncertainty includes a ±5% uncertainty in the activity measurement carried out by ICN. In a similar fashion, we determined that the value of the NIST 10Be standard (SRM4325) is (2.79 ± 0.03) × 10 -1110Be/ 9Be, within error of the certified value of (2.68 ± 0.14) × 10 -11. The Lawrence Livermore National Laboratory (LLNL) internal standards were also included in this study. We conclude that the 9Be(n, γ) neutron cross section is 7.8 ± 0.23 mb, without taking into account the uncertainty in the neutron irradiation.

  16. Distribution of standard deviation of an observable among superposed states

    NASA Astrophysics Data System (ADS)

    Yu, Chang-shui; Shao, Ting-ting; Li, Dong-mo

    2016-10-01

    The standard deviation (SD) quantifies the spread of the observed values on a measurement of an observable. In this paper, we study the distribution of SD among the different components of a superposition state. It is found that the SD of an observable on a superposition state can be well bounded by the SDs of the superposed states. We also show that the bounds also serve as good bounds on coherence of a superposition state. As a further generalization, we give an alternative definition of incompatibility of two observables subject to a given state and show how the incompatibility subject to a superposition state is distributed.

  17. Estimation of amplitude and standard deviation of noisy sinusoidal signals

    NASA Astrophysics Data System (ADS)

    Juarez-Salazar, Rigoberto; Diaz-Ramirez, Victor H.

    2017-01-01

    A simple method to estimate the amplitude and standard deviation of sinusoidal signals corrupted with additive Gaussian noise is proposed. For this, a two-parameter model is developed by sorting the samples of the signal. This reduced parametric model allows robust parameter estimation, even if the phase function of the sinusoid is nonlinear, discontinuous, and unknown. The functionality and performance of the proposed method are analyzed by several computer simulations; the used GNU Octave program is provided. The proposed method can be useful for unbiased envelope estimation in fringe pattern normalization among other potential applications.

  18. Vectorial statistics for the standard deviation of wind direction

    NASA Astrophysics Data System (ADS)

    Farrugia, Pierre S.; Micallef, Alfred

    2016-10-01

    The standard deviation of wind direction is an important parameter in atmospheric pollution management. It can be used to calculate the rate of horizontal diffusion and from this the transport and dispersion of air contaminants can be determined. The standard deviation of wind direction cannot be calculated directly from customary linear statistics, mainly because of its periodic nature which makes the zero position arbitrary. Various algorithms have been proposed to estimate its value. The methodologies adopted in meteorology implicitly assume that the wind angle can be treated independently of the wind speed. Such an assumption might not be appropriate in some instances, as will be shown in this work by means of an example. To overcome this limitation, a new algorithm that takes into account both the periodic and the vectorial nature of the wind direction will be proposed. This is done by weighing each sample value with the corresponding wind speed. The results obtained from the new method were compared to those determined from algorithms available in literature using measured data. The comparison indicates that while the behavior is similar, differences do exist. Further investigation indicated that while the differences can be small, they might be physically important.

  19. Image contrast enhancement based on a local standard deviation model

    SciTech Connect

    Chang, Dah-Chung; Wu, Wen-Rong

    1996-12-31

    The adaptive contrast enhancement (ACE) algorithm is a widely used image enhancement method, which needs a contrast gain to adjust high frequency components of an image. In the literature, the gain is usually inversely proportional to the local standard deviation (LSD) or is a constant. But these cause two problems in practical applications, i.e., noise overenhancement and ringing artifact. In this paper a new gain is developed based on Hunt`s Gaussian image model to prevent the two defects. The new gain is a nonlinear function of LSD and has the desired characteristic emphasizing the LSD regions in which details are concentrated. We have applied the new ACE algorithm to chest x-ray images and the simulations show the effectiveness of the proposed algorithm.

  20. Absolute flux calibration of optical spectrophotometric standard stars

    NASA Technical Reports Server (NTRS)

    Colina, Luis; Bohlin, Ralph C.

    1994-01-01

    A method based on Landolt photometry in B and V is developed to correct for a wavelength independent offset of the absolute flux level of optical spectrophotometric standards. The method is based on synthetic photometry techniques in B and V and is accurate to approximately 1%. The correction method is verified by Hubble Space Telescope Faint Object Spectrograph absolute fluxes for five calibration stars, which agree with Landolt photometry to 0.5% in B and V.

  1. Spectral relative standard deviation: a practical benchmark in metabolomics.

    PubMed

    Parsons, Helen M; Ekman, Drew R; Collette, Timothy W; Viant, Mark R

    2009-03-01

    Metabolomics datasets, by definition, comprise of measurements of large numbers of metabolites. Both technical (analytical) and biological factors will induce variation within these measurements that is not consistent across all metabolites. Consequently, criteria are required to assess the reproducibility of metabolomics datasets that are derived from all the detected metabolites. Here we calculate spectrum-wide relative standard deviations (RSDs; also termed coefficient of variation, CV) for ten metabolomics datasets, spanning a variety of sample types from mammals, fish, invertebrates and a cell line, and display them succinctly as boxplots. We demonstrate multiple applications of spectral RSDs for characterising technical as well as inter-individual biological variation: for optimising metabolite extractions, comparing analytical techniques, investigating matrix effects, and comparing biofluids and tissue extracts from single and multiple species for optimising experimental design. Technical variation within metabolomics datasets, recorded using one- and two-dimensional NMR and mass spectrometry, ranges from 1.6 to 20.6% (reported as the median spectral RSD). Inter-individual biological variation is typically larger, ranging from as low as 7.2% for tissue extracts from laboratory-housed rats to 58.4% for fish plasma. In addition, for some of the datasets we confirm that the spectral RSD values are largely invariant across different spectral processing methods, such as baseline correction, normalisation and binning resolution. In conclusion, we propose spectral RSDs and their median values contained herein as practical benchmarks for metabolomics studies.

  2. Analysis of standard reference materials by absolute INAA

    SciTech Connect

    Heft, R.E.; Koszykowski, R.F.

    1981-07-01

    Three standard reference materials, flyash, soil, and ASI 4340 steel, were analyzed by a method of absolute instrumental neutron activation analysis (INAA). Two different light water pool-type reactors were used to produce equivalent analytical results even though the epithermal to thermal flux ratio in one reactor was higher than that in the other by a factor of two.

  3. 1 CFR 21.14 - Deviations from standard organization of the Code of Federal Regulations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... CODIFICATION General Numbering § 21.14 Deviations from standard organization of the Code of Federal Regulations. (a) Any deviation from standard Code of Federal Regulations designations must be approved in advance... 1 General Provisions 1 2012-01-01 2012-01-01 false Deviations from standard organization of...

  4. 1 CFR 21.14 - Deviations from standard organization of the Code of Federal Regulations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... CODIFICATION General Numbering § 21.14 Deviations from standard organization of the Code of Federal Regulations. (a) Any deviation from standard Code of Federal Regulations designations must be approved in advance... 1 General Provisions 1 2011-01-01 2011-01-01 false Deviations from standard organization of...

  5. 1 CFR 21.14 - Deviations from standard organization of the Code of Federal Regulations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... CODIFICATION General Numbering § 21.14 Deviations from standard organization of the Code of Federal Regulations. (a) Any deviation from standard Code of Federal Regulations designations must be approved in advance... 1 General Provisions 1 2013-01-01 2012-01-01 true Deviations from standard organization of...

  6. 1 CFR 21.14 - Deviations from standard organization of the Code of Federal Regulations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... CODIFICATION General Numbering § 21.14 Deviations from standard organization of the Code of Federal Regulations. (a) Any deviation from standard Code of Federal Regulations designations must be approved in advance... 1 General Provisions 1 2010-01-01 2010-01-01 false Deviations from standard organization of...

  7. 1 CFR 21.14 - Deviations from standard organization of the Code of Federal Regulations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... CODIFICATION General Numbering § 21.14 Deviations from standard organization of the Code of Federal Regulations. (a) Any deviation from standard Code of Federal Regulations designations must be approved in advance... 1 General Provisions 1 2014-01-01 2012-01-01 true Deviations from standard organization of...

  8. Standardization of the cumulative absolute velocity. Final report

    SciTech Connect

    O`Hara, T.F.; Jacobson, J.P.

    1991-12-01

    EPRI NP-5930, ``A Criterion for Determining Exceedance of the Operating Basis Earthquake,`` was published in July 1988. As defined in that report, the Operating Basis Earthquake (OBE) is exceeded when both a response spectrum parameter and a second damage parameter, referred to as the Cumulative Absolute Velocity (CAV), are exceeded. In the review process of the above report, it was noted that the calculation of CAV could be confounded by time history records of long duration containing low (nondamaging) acceleration. Therefore, it is necessary to standardize the method of calculating CAV to account for record length. This standardized methodology allows consistent comparisons between future CAV calculations and the adjusted CAV threshold value based upon applying the standardized methodology to the data set presented in EPRI NP-5930. The recommended method to standardize the CAV calculation is to window its calculation on a second-by-second basis for a given time history. If the absolute acceleration exceeds 0.025g at any time during each one second interval, the earthquake records used in EPRI NP-5930 have been reanalyzed and the adjusted threshold of damage for CAV was found to be 0.16g-set.

  9. HST Stellar Standards with 1% Accuracy in Absolute Flux

    NASA Astrophysics Data System (ADS)

    Bohlin, R. C.

    2007-04-01

    Free of any atmospheric contamination, the {Hubble Space Telescope} provides the best available spectrophotometry from the far-UV to the near-IR for stars as faint as V˜16. The HST CALSPEC standard star network is based on three standard candles: the hot, pure hydrogen white dwarf (WD) stars G 191B2B, GD 153, and GD 71, which have Hubeny NLTE flux calculations that require the atomic physics for only one atom. These model flux distributions are normalized to the absolute flux for Vega of 3.46×10-9 erg cm-2 s-1 Å-1 at 5556 Å using precise Landolt V band photometry and the V bandpass function corrected for atmospheric transmission by M. Cohen. The three primary WD standards provide absolute flux calibrations for FOS, STIS and NICMOS spectrophotometry from these instruments on the HST. About 32 stellar spectral energy distributions (SEDs) have been constructed with a primary pedigree from the STIS data, which extends from 1150 Å for the hot stars to a long wavelength limit of 1 μm. NICMOS grism spectrophotometry provides an extension to 1.9 μm in the IR for 17 of the HST standards and longward to 2.5 μm for a few of the brighter stars. Included among these HST standards are Vega, the Sloan standard BD+17 4708, three bright solar analog candidates, three cool stars of type M or later, and five hot WDs. In addition, four K giants and four main sequence A-stars have NICMOS spectrophotometry from 0.8-2.5 μm. The WD fluxes are compared to their modeled SEDs and demonstrate an internal precision of 1-2%, while the A-stars agree with the Cohen IR fluxes to ˜2%. Three solar analog candidate stars differ from the solar spectrum by up to 10% in the region of heavy line blanketing from 3000-4000 Å and show differences in shape of ˜5% in the IR around 1.8 μm.

  10. Monochromator-Based Absolute Calibration of a Standard Radiation Thermometer

    NASA Astrophysics Data System (ADS)

    Mantilla, J. M.; Hernanz, M. L.; Campos, J.; Martín, M. J.; Pons, A.; del Campo, D.

    2014-04-01

    Centro Español de Metrología (CEM) is disseminating the International Temperature Scale (ITS-90), at high temperatures, by using the fixed points of Ag and Cu and a standard radiation thermometer. However, the future mise-en-pratique for the definition of the kelvin ( MeP-K) will include the dissemination of the kelvin by primary methods and by indirect approximations capable of exceptionally low uncertainties or increased reliability. Primary radiometry is, at present, able to achieve uncertainties competitive with the ITS-90 above the silver point with one of the possible techniques the calibration for radiance responsivity of an imaging radiometer (radiance method). In order to carry out this calibration, IO-CSIC (Spanish Designated Institute for luminous intensity and luminous flux) has collaborated with CEM, allowing traceability to its cryogenic radiometer. A monochromator integrating sphere-based spectral comparator facility has been used to calibrate one of the CEM standard radiation thermometers. The absolute calibrated standard radiation thermometer has been used to determine the temperatures of the fixed points of Cu, Co-C, Pt-C, and Re-C. The results obtained are 1357.80 K, 1597.10 K, 2011.66 K, and 2747.64 K, respectively, with uncertainties ranging from 0.4 K to 1.1 K.

  11. 75 FR 383 - Canned Pacific Salmon Deviating From Identity Standard; Extension of Temporary Permit for Market...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-05

    ...-2008-N-0119] Canned Pacific Salmon Deviating From Identity Standard; Extension of Temporary Permit for.... standard of identity for canned Pacific salmon. The extension will allow the permit holder to continue to... the standard of identity for canned Pacific salmon that was submitted by Yardarm Knot Fisheries,...

  12. 75 FR 67093 - Iceberg Water Deviating From Identity Standard; Temporary Permit for Market Testing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-01

    .... standard of identity for bottled water. The purpose of the temporary permit is to allow the applicant to... Rare Iceberg Water'' that deviate from the U.S. standard of identity for bottled water (Sec. 165.110... 101.9. The bottled water must be manufactured in accordance with the quality standards in Sec....

  13. Repeatability and Reproducibility Standard Deviations in the Measurement of Trace Moisture Generated Using Permeation Tubes

    PubMed Central

    Huang, Peter H.; Kacker, Raghu

    2003-01-01

    Permeation-tube moisture generators are used in industry as calibrated sources of water vapor and carrier gas mixtures. Measurements were made using three permeation-tube moisture generators of the type used in the semiconductor industry. This paper describes repeatability and reproducibility standard deviations in measurement of moisture concentration from such generators. Repeatability refers to measurements within a system and reproducibility refers to measurements between systems. Two independent methods were used to measure the realized concentration of water vapor. The first measurement, the calculated value, was determined using calibrated permeation rate of permeation-tube and flow rate of dry carrier gas. This is the industrial method of evaluating moisture concentration. The second measurement, the measured value, was determined using the low frost-point generator at the National Institute of Standards and Technology (NIST) and a quartz-crystal-micro-balance. Four pairs of independent measurements for each generator and for six nominal levels in the range from10 nL/L to 100 nL/L were made. The characteristic used to quantify repeatability and reproducibility standard deviations in industrial measurements is the calculated value minus the measured value. Repeatability standard deviation ranges from 1 nL/L to 2 nL/L, approximately. Reproducibility standard deviation ranges from 2 nL/L to 8 nL/L, approximately. The documentary ASTM standard E691-99 was used for both data validation and quantification of the repeatability and reproducibility standard deviations. PMID:27413608

  14. On the Linear Relation between the Mean and the Standard Deviation of a Response Time Distribution

    ERIC Educational Resources Information Center

    Wagenmakers, Eric-Jan; Brown, Scott

    2007-01-01

    Although it is generally accepted that the spread of a response time (RT) distribution increases with the mean, the precise nature of this relation remains relatively unexplored. The authors show that in several descriptive RT distributions, the standard deviation increases linearly with the mean. Results from a wide range of tasks from different…

  15. Estimating maize water stress by standard deviation of canopy temperature in thermal imagery

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A new crop water stress index using standard deviation of canopy temperature as an input was developed to monitor crop water status. In this study, thermal imagery was taken from maize under various levels of deficit irrigation treatments in different crop growing stages. The Expectation-Maximizatio...

  16. A passive autofocus system by using standard deviation of the image on a liquid lens

    NASA Astrophysics Data System (ADS)

    Rasti, Pejman; Kesküla, Arko; Haus, Henry; Schlaak, Helmut F.; Anbarjafari, Gholamreza; Aabloo, Alvo; Kiefer, Rudolf

    2015-04-01

    Today most of applications have a small camera such as cell phones, tablets and medical devices. A micro lens is required in order to reduce the size of the devices. In this paper an auto focus system is used in order to find the best position of a liquid lens without any active components such as ultrasonic or infrared. In fact a passive auto focus system by using standard deviation of the images on a liquid lens which consist of a Dielectric Elastomer Actuator (DEA) membrane between oil and water is proposed.

  17. Standard Deviation and Intra Prediction Mode Based Adaptive Spatial Error Concealment (SEC) in H.264/AVC

    NASA Astrophysics Data System (ADS)

    Wang, Jun; Wang, Lei; Ikenaga, Takeshi; Goto, Satoshi

    Transmission of compressed video over error prone channels may result in packet losses or errors, which can significantly degrade the image quality. Therefore an error concealment scheme is applied at the video receiver side to mask the damaged video. Considering there are 3 types of MBs (Macro Blocks) in natural video frame, i. e., Textural MB, Edged MB, and Smooth MB, this paper proposes an adaptive spatial error concealment which can choose 3 different methods for these 3 different MBs. For criteria of choosing appropriate method, 2 factors are taken into consideration. Firstly, standard deviation of our proposed edge statistical model is exploited. Secondly, some new features of latest video compression standard H.264/AVC, i. e., intra prediction mode is also considered for criterion formulation. Compared with previous works, which are only based on deterministic measurement, proposed method achieves the best image recovery. Subjective and objective image quality evaluations in experiments confirmed this.

  18. A standard deviation selection in evolutionary algorithm for grouper fish feed formulation

    NASA Astrophysics Data System (ADS)

    Cai-Juan, Soong; Ramli, Razamin; Rahman, Rosshairy Abdul

    2016-10-01

    Malaysia is one of the major producer countries for fishery production due to its location in the equatorial environment. Grouper fish is one of the potential markets in contributing to the income of the country due to its desirable taste, high demand and high price. However, the demand of grouper fish is still insufficient from the wild catch. Therefore, there is a need to farm grouper fish to cater to the market demand. In order to farm grouper fish, there is a need to have prior knowledge of the proper nutrients needed because there is no exact data available. Therefore, in this study, primary data and secondary data are collected even though there is a limitation of related papers and 30 samples are investigated by using standard deviation selection in Evolutionary algorithm. Thus, this study would unlock frontiers for an extensive research in respect of grouper fish feed formulation. Results shown that the fitness of standard deviation selection in evolutionary algorithm is applicable. The feasible and low fitness, quick solution can be obtained. These fitness can be further predicted to minimize cost in farming grouper fish.

  19. Scatter-Reducing Sounding Filtration Using a Genetic Algorithm and Mean Monthly Standard Deviation

    NASA Technical Reports Server (NTRS)

    Mandrake, Lukas

    2013-01-01

    Retrieval algorithms like that used by the Orbiting Carbon Observatory (OCO)-2 mission generate massive quantities of data of varying quality and reliability. A computationally efficient, simple method of labeling problematic datapoints or predicting soundings that will fail is required for basic operation, given that only 6% of the retrieved data may be operationally processed. This method automatically obtains a filter designed to reduce scatter based on a small number of input features. Most machine-learning filter construction algorithms attempt to predict error in the CO2 value. By using a surrogate goal of Mean Monthly STDEV, the goal is to reduce the retrieved CO2 scatter rather than solving the harder problem of reducing CO2 error. This lends itself to improved interpretability and performance. This software reduces the scatter of retrieved CO2 values globally based on a minimum number of input features. It can be used as a prefilter to reduce the number of soundings requested, or as a post-filter to label data quality. The use of the MMS (Mean Monthly Standard deviation) provides a much cleaner, clearer filter than the standard ABS(CO2-truth) metrics previously employed by competitor methods. The software's main strength lies in a clearer (i.e., fewer features required) filter that more efficiently reduces scatter in retrieved CO2 rather than focusing on the more complex (and easily removed) bias issues.

  20. Absolute Infrared Calibration of Standard Stars by the Midcourse Space Experiment

    DTIC Science & Technology

    2004-04-01

    fluxes of standard stars. Using standard stars to calibrate space- and ground-based observations of astronomical sources and Earth satellites has the... Satellite (IRAS). "* Cohen et al. (1 992a; Paper I) derived the absolute infrared flux for a Lyr by extrapolating the recommended visual flux of Hayes... characterized spectral bands. Cohen et al. (1992a) assigned the 1.45 percent uncertainty derived by Hayes (1985) for the calibration in the visual to the

  1. STANDARDIZING TYPE Ia SUPERNOVA ABSOLUTE MAGNITUDES USING GAUSSIAN PROCESS DATA REGRESSION

    SciTech Connect

    Kim, A. G.; Aldering, G.; Aragon, C.; Bailey, S.; Childress, M.; Fakhouri, H. K.; Nordin, J.; Thomas, R. C.; Antilogus, P.; Bongard, S.; Canto, A.; Cellier-Holzem, F.; Guy, J.; Baltay, C.; Buton, C.; Kerschhaggl, M.; Kowalski, M.; Chotard, N.; Copin, Y.; Gangler, E.; and others

    2013-04-01

    We present a novel class of models for Type Ia supernova time-evolving spectral energy distributions (SEDs) and absolute magnitudes: they are each modeled as stochastic functions described by Gaussian processes. The values of the SED and absolute magnitudes are defined through well-defined regression prescriptions, so that data directly inform the models. As a proof of concept, we implement a model for synthetic photometry built from the spectrophotometric time series from the Nearby Supernova Factory. Absolute magnitudes at peak B brightness are calibrated to 0.13 mag in the g band and to as low as 0.09 mag in the z = 0.25 blueshifted i band, where the dispersion includes contributions from measurement uncertainties and peculiar velocities. The methodology can be applied to spectrophotometric time series of supernovae that span a range of redshifts to simultaneously standardize supernovae together with fitting cosmological parameters.

  2. Repeatable source, site, and path effects on the standard deviation for empirical ground-motion prediction models

    USGS Publications Warehouse

    Lin, P.-S.; Chiou, B.; Abrahamson, N.; Walling, M.; Lee, C.-T.; Cheng, C.-T.

    2011-01-01

    In this study, we quantify the reduction in the standard deviation for empirical ground-motion prediction models by removing ergodic assumption.We partition the modeling error (residual) into five components, three of which represent the repeatable source-location-specific, site-specific, and path-specific deviations from the population mean. A variance estimation procedure of these error components is developed for use with a set of recordings from earthquakes not heavily clustered in space.With most source locations and propagation paths sampled only once, we opt to exploit the spatial correlation of residuals to estimate the variances associated with the path-specific and the source-location-specific deviations. The estimation procedure is applied to ground-motion amplitudes from 64 shallow earthquakes in Taiwan recorded at 285 sites with at least 10 recordings per site. The estimated variance components are used to quantify the reduction in aleatory variability that can be used in hazard analysis for a single site and for a single path. For peak ground acceleration and spectral accelerations at periods of 0.1, 0.3, 0.5, 1.0, and 3.0 s, we find that the singlesite standard deviations are 9%-14% smaller than the total standard deviation, whereas the single-path standard deviations are 39%-47% smaller.

  3. Estimating wind velocity standard deviation values in the inertial sublayer from observations in the roughness sublayer

    NASA Astrophysics Data System (ADS)

    Falabino, Simona; Trini Castelli, Silvia

    2017-02-01

    In air quality practice, observed data are often input to air pollution models to simulate the pollutants dispersion and to estimate their concentration. When the area of interest includes urban sites, observed data collected at urban or suburban stations can be available, and it can happen to use them for estimating surface layer parameters given in input to the models. In such case, roughness sublayer quantities may enter the parameterizations of the turbulence variables as if they were representative of the inertial sublayer, possibly leading to a not appropriate application of the Monin-Obukhov similarity theory. We investigate whether it is possible to derive suitable values of the wind velocity standard deviations for the inertial sublayer using the friction velocity and stability parameter observed in the roughness sublayer, inside a similarity-like analytical function. For this purpose, an analysis of sonic anemometer data sets collected in suburban and urban sites is proposed. The values derived through this approach are compared to actual observations in the inertial sublayer. The transferability of the empirical coefficients estimated for the similarity functions between different sites, characterized by similar or different morphologies, is also addressed. The derived functions proved to be a reasonable approximation of the actual data. This method was found to be feasible and generally reliable, and can be a reference to keep using, in air pollution models, the similarity theory parameterizations when measurements are available only in the roughness sublayer.

  4. A better detection of 2LSB steganography via standard deviation of the extended pairs of values

    NASA Astrophysics Data System (ADS)

    Khalind, Omed; Aziz, Benjamin

    2015-05-01

    This paper proposes a modification to the Extended Pairs of Values (EPoV) method of 2LSB steganalysis in digital still images. In EPoV, the detection and the estimation of the hidden message length were performed in two separate processes as it considered the automated detection. However, the new proposed method uses the standard deviation of the EPoV to measure the amount of distortion in the stego image made by the embedding process using 2LSB replacement, which is directly proportional with the embedding rate. It is shown that it can accurately estimate the length of the hidden message and outperform the other methods of the targeted 2LSB steganalysis in the literature. The proposed method is also more consistent with the steganalysis methods in the literature by giving the amount of difference to the expected clean image. According to the experimental results, based on analysing 3000 nevercompressed images, the proposed method is more accurate than the current targeted 2LSB steganalysis methods for low embedding rates.

  5. Delay and Standard Deviation Beamforming to Enhance Specular Reflections in Ultrasound Imaging.

    PubMed

    Bandaru, Raja Sekhar; Sornes, Anders Rasmus; Hermans, Jeroen; Samset, Eigil; D'hooge, Jan

    2016-12-01

    Although interventional devices, such as needles, guide wires, and catheters, are best visualized by X-ray, real-time volumetric echography could offer an attractive alternative as it avoids ionizing radiation; it provides good soft tissue contrast, and it is mobile and relatively cheap. Unfortunately, as echography is traditionally used to image soft tissue and blood flow, the appearance of interventional devices in conventional ultrasound images remains relatively poor, which is a major obstacle toward ultrasound-guided interventions. The objective of this paper was therefore to enhance the appearance of interventional devices in ultrasound images. Thereto, a modified ultrasound beamforming process using conventional-focused transmit beams is proposed that exploits the properties of received signals containing specular reflections (as arising from these devices). This new beamforming approach referred to as delay and standard deviation beamforming (DASD) was quantitatively tested using simulated as well as experimental data using a linear array transducer. Furthermore, the influence of different imaging settings (i.e., transmit focus, imaging depth, and scan angle) on the obtained image contrast was evaluated. The study showed that the image contrast of specular regions improved by 5-30 dB using DASD beamforming compared with traditional delay and sum (DAS) beamforming. The highest gain in contrast was observed when the interventional device was tilted away from being orthogonal to the transmit beam, which is a major limitation in standard DAS imaging. As such, the proposed beamforming methodology can offer an improved visualization of interventional devices in the ultrasound image with potential implications for ultrasound-guided interventions.

  6. Delay and Standard Deviation beamforming to enhance specular reflections in Ultrasound Imaging.

    PubMed

    Bandaru, Raja Sekhar; Sornes, Anders; Hermans, Jeroen; Samset, Eigil; D'hooge, Jan

    2016-09-27

    Although interventional devices such as needles, guide wires and catheters are best visualized by X-ray, real-time volumetric echography could offer an attractive alternative as it avoids ionizing radiation; it provides good soft tissue contrast and it is mobile and relatively cheap. Unfortunately, as echography is traditionally used to image soft tissue and blood flow, the appearance of interventional devices in conventional ultrasound images remains relatively poor which is a major obstacle towards ultrasound-guided interventions. The objective of the current study was therefore to enhance the appearance of interventional devices in ultrasound images. Thereto a modified ultrasound beamforming process using conventional focused transmit beams is proposed that exploits the properties of received signals containing specular reflections (as arising from these devices). This new beamforming approach referred to as Delay and Standard Deviation beamforming (DASD) was quantitatively tested using simulated as well as experimental data using a linear array transducer. Furthermore, the influence of different imaging settings (i.e. transmit focus, imaging depth and scan angle) on the obtained image contrast was evaluated. The study showed that the image contrast of specular regions improved by 5 to 30dB using DASD beamforming compared to traditional delay and sum (DAS) beamforming. The highest gain in contrast was observed when the interventional device was tilted away from being orthogonal to the transmit beam, which is a major limitation in standard DAS imaging. As such, the proposed beamforming methodology can offer an improved visualization of interventional devices in the ultrasound image with potential implications for ultrasound-guided interventions.

  7. Intercomparison of the LBIR Absolute Cryogenic Radiometers to the NIST Optical Power Measurement Standard

    PubMed Central

    Fedchak, James A.; Carter, Adriaan C.; Datla, Raju

    2006-01-01

    The Low Background Infrared calibration (LBIR) facility at the National Institute of Standards and Technology (NIST) presently maintains four absolute cryogenic radiometers (ACRs) which serve as standard reference detectors for infrared calibrations performed by the facility. The primary standard for optical power measurements at NIST-Gaithersburg has been the High Accuracy Cryogenic Radiometer (HACR). Recently, an improved radiometer, the Primary Optical Watt Radiometer (POWR), has replaced the HACR as the primary standard. In this paper, we present the results of comparisons between the radiometric powers measured by the four ACRs presently maintained by the LBIR facility to that measured by the HACR and POWR. This was done by using a Si photodiode light-trapping detector as a secondary transfer standard to compare the primary national standards to the ACRs maintained by the LBIR facility. The technique used to compare an ACR to the trap detector is described in detail. The absolute optical power measurements are found to be within 0.1 % of the primary standard for all the ACRs examined in this study. PMID:27274936

  8. Prospects for the Moon as an SI-Traceable Absolute Spectroradiometric Standard for Satellite Remote Sensing

    NASA Astrophysics Data System (ADS)

    Cramer, C. E.; Stone, T. C.; Lykke, K.; Woodward, J. T.

    2015-12-01

    The Earth's Moon has many physical properties that make it suitable for use as a reference light source for radiometric calibration of remote sensing satellite instruments. Lunar calibration has been successfully applied to many imagers in orbit, including both MODIS instruments and NPP-VIIRS, using the USGS ROLO model to predict the reference exoatmospheric lunar irradiance. Sensor response trending was developed for SeaWIFS with a relative accuracy better than 0.1 % per year with lunar calibration techniques. However, the Moon rarely is used as an absolute reference for on-orbit calibration, primarily due to uncertainties in the ROLO model absolute scale of 5%-10%. But this limitation lies only with the models - the Moon itself is radiometrically stable, and development of a high-accuracy absolute lunar reference is inherently feasible. A program has been undertaken by NIST to collect absolute measurements of the lunar spectral irradiance with absolute accuracy <1 % (k=2), traceable to SI radiometric units. Initial Moon observations were acquired from the Whipple Observatory on Mt. Hopkins, Arizona, elevation 2367 meters, with continuous spectral coverage from 380 nm to 1040 nm at ~3 nm resolution. The lunar spectrometer acquired calibration measurements several times each observing night by pointing to a calibrated integrating sphere source. The lunar spectral irradiance at the top of the atmosphere was derived from a time series of ground-based measurements by a Langley analysis that incorporated measured atmospheric conditions and ROLO model predictions for the change in irradiance resulting from the changing Sun-Moon-Observer geometry throughout each night. Two nights were selected for further study. An extensive error analysis, which includes instrument calibration and atmospheric correction terms, shows a combined standard uncertainty under 1 % over most of the spectral range. Comparison of these two nights' spectral irradiance measurements with predictions

  9. Dreams of a Final System: Origins of the Quest for an Absolute Standard

    NASA Astrophysics Data System (ADS)

    Crease, Robert

    2012-02-01

    The first attempts to find unchanging phenomena that could be used to evaluate the accuracy of standards and recreate them if lost predated the metric system. As early as the seventeenth century, members of the French Academy and British Royal Society sought to use the seconds pendulum and the Earth's meridian as tethers for length standards. These efforts ultimately failed. The vision of an absolute standard was revived in the 1870s, when C. S. Peirce was the first to experimentally tie a unit, the meter, to a natural standard, the wavelength of a spectral line, using a diffraction grating. This work inspired A. Michelson and E. Morley, in the 1880s, to apply the interferometer with which they were attempting to detect ether drift to this purpose. Michelson further pursued this work at the BIPM in 1892, which set the stage for the later redefinition, in 1960, of the meter in terms of the wavelength of a spectral line.

  10. Transverse flowmetry of carbon particles based on photoacoustic Doppler standard deviation using an auto-correlation method

    NASA Astrophysics Data System (ADS)

    Lu, Tao; Sun, Li-jun

    2015-05-01

    In order to measure the flow velocity of carbon particle suspension perpendicular to the receiving axis of ultrasound transducer, the standard deviation of photoacoustic Doppler frequency spectrum is used to estimate the bandwidth broadening, and the spectrum standard deviation is calculated by an auto-correlation method. A 532 nm pulsed laser with the repetition rate of 20 Hz is used as a pumping source to generate photoacoustic signal. The photoacoustic signals are detected using a focused PZT ultrasound transducer with the central frequency of 10 MHz. The suspension of carbon particles is driven by a syringe pump. The complex photoacoustic signal is calculated by Hilbert transformation from time domain signal before auto-correlation. The standard deviation of the Doppler bandwidth broadening is calculated by averaging the auto-correlation results of several individual A scans. The feasibility of the proposed method is demonstrated by measuring the spectrum standard deviation of the transversal carbon particle flow from 5.0 mm/s to 8.4 mm/s. The experimental results show that the auto-correlation result is approximately linearly distributed within the measuring range.

  11. Normabweichungen im Zeitungsdeutsch Ostbelgiens (Deviations from the Standard in the Newspaper German of East Belgium)

    ERIC Educational Resources Information Center

    Nelde, Peter H.

    1974-01-01

    Concludes that the German used in the east Belgium newspaper differs fr om standard High German. Proceeds to list these differences in the areas of lexicology, semantics and stylistics, morphology and syntax, orthography e tc. (Text is in German.) (DS)

  12. 7 CFR 1724.52 - Permitted deviations from RUS construction standards.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... raptor protection in the design of overhead line structures is required by RUS; a Federal, State or local... conductor on overhead distribution lines. (1) It is permissible to lower the neutral attachment on standard... trucks designed for such work....

  13. 7 CFR 1724.52 - Permitted deviations from RUS construction standards.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... raptor protection in the design of overhead line structures is required by RUS; a Federal, State or local... conductor on overhead distribution lines. (1) It is permissible to lower the neutral attachment on standard... trucks designed for such work....

  14. 7 CFR 1724.52 - Permitted deviations from RUS construction standards.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... raptor protection in the design of overhead line structures is required by RUS; a Federal, State or local... conductor on overhead distribution lines. (1) It is permissible to lower the neutral attachment on standard... trucks designed for such work....

  15. 7 CFR 1724.52 - Permitted deviations from RUS construction standards.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... raptor protection in the design of overhead line structures is required by RUS; a Federal, State or local... conductor on overhead distribution lines. (1) It is permissible to lower the neutral attachment on standard... trucks designed for such work....

  16. 7 CFR 1724.52 - Permitted deviations from RUS construction standards.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... raptor protection in the design of overhead line structures is required by RUS; a Federal, State or local... conductor on overhead distribution lines. (1) It is permissible to lower the neutral attachment on standard... trucks designed for such work....

  17. Absolute fluorescence measurements > 1000 nm: setup design, calibration and standards (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Resch-Genger, Ute; Würth, Christian; Pauli, Jutta; Hatami, Soheil; Kaiser, Martin

    2016-03-01

    There is an increasing interest in optical reporters like semiconductor quantum dots and upconversion nanophosphors with emission < 1000 nm for bioanalysis, medical diagnostics, and safety barcodes and hence, in reliable fluorescence measurements in this wavelength region, e.g., for the comparison of material performance and the rational design of new nanomaterials with improved properties [1-4]. The performance of fluorescence measurements < 800 nm and especially < 1000 nm is currently hampered by the lack of suitable methods and standards for the simple determination of the wavelength-dependent spectral responsivity of fluorescence measuring systems and the control of measured emission spectra and intensities [3-5]. This is of special relevance for nanocrystalline emitters like quantum dots and rods as well as for upconversion nanocrystals, where surface states and the accessibility of emissive states by quenchers largely control accomplishable quantum yields and hence, signal sizes and detection sensitivities from the reporter side. Here, we present the design of an integrating sphere setup for the absolute measurement of emission spectra and quantum yields in the wavelength region of 650 to 1600 nm and its calibration as well as examples for potential fluorescence standards from different reporter classes for the control of the reliability of such measurements [5]. This includes new spectral fluorescence standards for the wavelength region of 650 nm to 1000 nm as well as a set of quantum yield standards covering the wavelength region from 400 nm to 1000 nm.

  18. Methodological Issues in Meta-Analyzing Standard Deviations: Comment on Bond and DePaulo (2008)

    ERIC Educational Resources Information Center

    Pigott, Therese D.; Wu, Meng-Jia

    2008-01-01

    In this comment on C. F. Bond and B. M. DePaulo, the authors raise methodological concerns about the approach used to analyze the data. The authors suggest further refinement of the procedures used, and they compare the approach taken by Bond and DePaulo with standard methods for meta-analysis. (Contains 1 table and 2 figures.)

  19. Constraint on Absolute Accuracy of Metacomprehension Assessments: The Anchoring and Adjustment Model vs. the Standards Model

    ERIC Educational Resources Information Center

    Kwon, Heekyung

    2011-01-01

    The objective of this study is to provide a systematic account of three typical phenomena surrounding absolute accuracy of metacomprehension assessments: (1) the absolute accuracy of predictions is typically quite low; (2) there exist individual differences in absolute accuracy of predictions as a function of reading skill; and (3) postdictions…

  20. NIST Standard Reference Material 3600: Absolute Intensity Calibration Standard for Small-Angle X-ray Scattering

    PubMed Central

    Zhang, Fan; Kline, R. Joseph; Guthrie, William F.; Ilavsky, Jan

    2017-01-01

    The certification of a new standard reference material for small-angle scattering [NIST Standard Reference Material (SRM) 3600: Absolute Intensity Calibration Standard for Small-Angle X-ray Scattering (SAXS)], based on glassy carbon, is presented. Creation of this SRM relies on the intrinsic primary calibration capabilities of the ultra-small-angle X-ray scattering technique. This article describes how the intensity calibration has been achieved and validated in the certified Q range, Q = 0.008–0.25 Å−1, together with the purpose, use and availability of the SRM. The intensity calibration afforded by this robust and stable SRM should be applicable universally to all SAXS instruments that employ a transmission measurement geometry, working with a wide range of X-ray energies or wavelengths. The validation of the SRM SAXS intensity calibration using small-angle neutron scattering (SANS) is discussed, together with the prospects for including SANS in a future renewal certification. PMID:28381972

  1. The IAG solar flux atlas: Accurate wavelengths and absolute convective blueshift in standard solar spectra

    NASA Astrophysics Data System (ADS)

    Reiners, A.; Mrotzek, N.; Lemke, U.; Hinrichs, J.; Reinsch, K.

    2016-03-01

    We present a new solar flux atlas with the aim of understanding wavelength precision and accuracy in solar benchmark data. The atlas covers the wavelength range 405-2300 nm and was observed at the Institut für Astrophysik, Göttingen (IAG), with a Fourier transform spectrograph (FTS). In contrast to other FTS atlases, the entire visible wavelength range was observed simultaneously using only one spectrograph setting. We compare the wavelength solution of the new atlas to the Kitt Peak solar flux atlases and to the HARPS frequency-comb calibrated solar atlas. Comparison reveals systematics in the two Kitt Peak FTS atlases resulting from their wavelength scale construction, and shows consistency between the IAG and the HARPS atlas. We conclude that the IAG atlas is precise and accurate on the order of ± 10 m s-1 in the wavelength range 405-1065 nm, while the Kitt Peak atlases show deviations as large as several ten to 100 m s-1. We determine absolute convective blueshift across the spectrum from the IAG atlas and report slight differences relative to results from the Kitt Peak atlas that we attribute to the differences between wavelength scales. We conclude that benchmark solar data with accurate wavelength solution are crucial to better understand the effect of convection on stellar radial velocity measurements, which is one of the main limitations of Doppler spectroscopy at m s -1 precision. Data (FITS files of the spectra) and Table A.1 are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/587/A65

  2. A BAYESIAN METHOD FOR CALCULATING REAL-TIME QUANTITATIVE PCR CALIBRATION CURVES USING ABSOLUTE PLASMID DNA STANDARDS

    EPA Science Inventory

    In real-time quantitative PCR studies using absolute plasmid DNA standards, a calibration curve is developed to estimate an unknown DNA concentration. However, potential differences in the amplification performance of plasmid DNA compared to genomic DNA standards are often ignore...

  3. An improved offset generator developed for Allan deviation measurement of ultra stable frequency standards

    NASA Technical Reports Server (NTRS)

    Hamell, Robert L.; Kuhnle, Paul F.; Sydnor, Richard L.

    1992-01-01

    Measuring the performance of ultra stable frequency standards such as the Superconducting Cavity Maser Oscillator (SCMO) necessitates improvement of some test instrumentation. The frequency stability test equipment used at JPL includes a 1 Hz Offset Generator to generate a beat frequency between a pair of 100 MHz signals that are being compared. The noise floor of the measurement system using the current Offset Generator is adequate to characterize stability of hydrogen masers, but it is not adequate for the SCMO. A new Offset Generator with improved stability was designed and tested at JPL. With this Offset Generator and a new Zero Crossing Detector, recently developed at JPL, the measurement flow was reduced by a factor of 5.5 at 1 second tau, 3.0 at 1000 seconds, and 9.4 at 10,000 seconds, compared against the previous design. In addition to the new circuit designs of the Offset Generator and Zero Crossing Detector, tighter control of the measurement equipment environment was required to achieve this improvement. The design of this new Offset Generator are described, along with details of the environment control methods used.

  4. Using the Standard Deviation of a Region of Interest in an Image to Estimate Camera to Emitter Distance

    PubMed Central

    Cano-García, Angel E.; Lazaro, José Luis; Infante, Arturo; Fernández, Pedro; Pompa-Chacón, Yamilet; Espinoza, Felipe

    2012-01-01

    In this study, a camera to infrared diode (IRED) distance estimation problem was analyzed. The main objective was to define an alternative to measures depth only using the information extracted from pixel grey levels of the IRED image to estimate the distance between the camera and the IRED. In this paper, the standard deviation of the pixel grey level in the region of interest containing the IRED image is proposed as an empirical parameter to define a model for estimating camera to emitter distance. This model includes the camera exposure time, IRED radiant intensity and the distance between the camera and the IRED. An expression for the standard deviation model related to these magnitudes was also derived and calibrated using different images taken under different conditions. From this analysis, we determined the optimum parameters to ensure the best accuracy provided by this alternative. Once the model calibration had been carried out, a differential method to estimate the distance between the camera and the IRED was defined and applied, considering that the camera was aligned with the IRED. The results indicate that this method represents a useful alternative for determining the depth information. PMID:22778608

  5. Exploring a Black Body Source as an Absolute Radiometric Calibration Standard and Comparison with a NIST Traced Lamp Standard

    NASA Technical Reports Server (NTRS)

    Green, Robert O.; Chrien, Thomas; Sarture, Chuck

    2001-01-01

    Radiometric calibration of the Airborne Visible/Infrared Imaging Spectrometer (AVIRIS) is required for the scientific research and application objectives pursued with the spectroscopic measurements. Specifically calibration is required for: inter-comparison of AVIRIS data measured at different locations and at different times; analysis of AVIRIS data with data measured by other instruments; and analysis of AVIRIS data in conjunction with computer models. The primary effect of radiometric calibration is conversion of AVIRIS instrument response values (digitized numbers, or DN) to units of absolute radiance. For example, a figure shows the instrument response spectrum measured by AVIRIS over a portion of Rogers Dry Lake, California, and another figure shows the same spectrum calibrated to radiance. Only the calibrated spectrum may be quantitatively analyzed for science research and application objectives. Since the initial development of the AVIRIS instrument-radiometric calibration has been based upon a 1000-W irradiance lamp with a calibration traced to the National Institute of Standards and Technology (NIST). There are several advantages to this irradiance-lamp calibration approach. First, the considerable effort of NIST backs up the calibration. Second, by changing the distance to the lamp, the output can closely span the radiance levels measured by AVIRIS. Third, this type of standard is widely used. Fourth, these calibrated lamps are comparatively inexpensive. Conversely, there are several disadvantages to this approach as well. First, the lamp is not a primary standard. Second, the lamp output characteristics may change in an unknown manner through time. Third, it is difficult to assess, constrain, or improve the calibration uncertainty delivered with the lamp. In an attempt to explore the effect and potentially address some of these disadvantages a set of analyses and measurements comparing an irradiance lamp with a black-body source have been completed

  6. Relationship between Standard Deviation and Maximum Fluctuation Width of Ensemble Average Insolation Observed at Multi-points in Large Area

    NASA Astrophysics Data System (ADS)

    Kato, Takeyoshi; Inoue, Takato; Honda, Nobuyuki; Koaizawa, Kazumasa; Nishino, Shinichi; Suzuoki, Yasuo

    For the detailed impact assessment of the total power output fluctuation of high penetration photovoltaic power generation system in terms of the load-frequency control, this study evaluated the relationship between the standard deviation (STD) including only shorter cycles than 32 minute and the maximum fluctuation width (MFW) calculated with various window width by using the two data-sets of multi-points observed insolation data. The main results are as follows. The R2 of regression line of STD - MFW correlation diagram is larger than 0.85 for various seasons, while the slope of regression line slightly varies with seasons. The slope of regression line is almost the same for various area sizes during the same season, although the variation ranges of both STD and MFW reduce with larger window width due to a so-called smoothing effect. The results suggest that if the STD of geographical average insolation can be calculated by using stochastic method, the MFW can be calculated with a linear function of STD because of the good correlation between STD and MFW independently of seasons and area sizes.

  7. The recursive combination filter approach of pre-processing for the estimation of standard deviation of RR series.

    PubMed

    Mishra, Alok; Swati, D

    2015-09-01

    Variation in the interval between the R-R peaks of the electrocardiogram represents the modulation of the cardiac oscillations by the autonomic nervous system. This variation is contaminated by anomalous signals called ectopic beats, artefacts or noise which mask the true behaviour of heart rate variability. In this paper, we have proposed a combination filter of recursive impulse rejection filter and recursive 20% filter, with recursive application and preference of replacement over removal of abnormal beats to improve the pre-processing of the inter-beat intervals. We have tested this novel recursive combinational method with median method replacement to estimate the standard deviation of normal to normal (SDNN) beat intervals of congestive heart failure (CHF) and normal sinus rhythm subjects. This work discusses the improvement in pre-processing over single use of impulse rejection filter and removal of abnormal beats for heart rate variability for the estimation of SDNN and Poncaré plot descriptors (SD1, SD2, and SD1/SD2) in detail. We have found the 22 ms value of SDNN and 36 ms value of SD2 descriptor of Poincaré plot as clinical indicators in discriminating the normal cases from CHF cases. The pre-processing is also useful in calculation of Lyapunov exponent which is a nonlinear index as Lyapunov exponents calculated after proposed pre-processing modified in a way that it start following the notion of less complex behaviour of diseased states.

  8. Geographical Extent Feasible for Standard Deviation Calculation using 1/√N Rule regarding Ensemble Average Insolation Fluctuation

    NASA Astrophysics Data System (ADS)

    Kato, Takeyoshi; Inoue, Takato; Honda, Nobuyuki; Koaizawa, Kazumasa; Nishino, Shinichi; Suzuoki, Yasuo

    In this study, we evaluated the practical usability of so-called 1/√N rule, focusing on three factors, i.e. the geographical extent, the location of representative point, and the topological difference. First, by using the insolation data observed at 37 points mainly located in the Nobi Plain, we calculated the correlation diagram between two different standard deviations (STDs) of geographical average insolation fluctuation, i.e. STD of ensemble average insolation of N points (σe) and STD calculated with the representative point data by using 1/√N rule (σN). As the results of evaluating the slope and R2 values of regression line of correlation diagram and the P-value of χ2-test regarding frequency distribution of σe and σN, the 1/√N rule would be applicable for the area of around 20km radius. The representative point for calculating σN should be carefully selected even within the area of 15km radius. Because the difference in weather condition is much larger in the Matsumoto Basin area than in the Nobi Plain area even if the area size is the same, the 1/√N rule should be applied to smaller area than the area of 20km radius available for the Nobi Plain area.

  9. Standard deviation of the mean and other time series properties of voltages measured with a digital lock-in amplifier

    NASA Astrophysics Data System (ADS)

    Witt, Thomas J.; Fletcher, N. E.

    2010-10-01

    We investigate some statistical properties of ac voltages from a white noise source measured with a digital lock-in amplifier equipped with finite impulse response output filters which introduce correlations between successive voltage values. The main goal of this work is to propose simple solutions to account for correlations when calculating the standard deviation of the mean (SDM) for a sequence of measurement data acquired using such an instrument. The problem is treated by time series analysis based on a moving average model of the filtering process. Theoretical expressions are derived for the power spectral density (PSD), the autocorrelation function, the equivalent noise bandwidth and the Allan variance; all are related to the SDM. At most three parameters suffice to specify any of the above quantities: the filter time constant, the time between successive measurements (both set by the lock-in operator) and the PSD of the white noise input, h0. Our white noise source is a resistor so that the PSD is easily calculated; there are no free parameters. Theoretical expressions are checked against their respective sample estimates and, with the exception of two of the bandwidth estimates, agreement to within 11% or better is found.

  10. Absolute standardization of the impurity (121)Te associated to the production of the radiopharmaceutical (123)I.

    PubMed

    Araújo, M T F; Poledna, R; Delgado, J U; Silva, R L; Iwahara, A; da Silva, C J; Tauhata, L; Oliveira, A E; de Almeida, M C M; Lopes, R T

    2016-03-01

    (123)I is widely used for radiodiagnostic procedures. It is produced by reaction of (124)Xe (p,2n) (123)Cs →(123)Xe →(123)I in cyclotrons. (121)Te and (125)I appear in a photon energy spectrum as impurities. An activity of (121)Te was calibrated absolutely by sum-peak method and its photon emitting probability was estimated, whose results were consistent with published results.

  11. SOLAR/SOLSPEC: Scientific Objectives, Instrument Performance and Its Absolute Calibration Using a Blackbody as Primary Standard Source

    NASA Astrophysics Data System (ADS)

    Thuillier, G.; Foujols, T.; Bolsée, D.; Gillotay, D.; Hersé, M.; Peetermans, W.; Decuyper, W.; Mandel, H.; Sperfeld, P.; Pape, S.; Taubert, D. R.; Hartmann, J.

    2009-06-01

    SOLAR is a set of three solar instruments measuring the total and spectral absolute irradiance from 16 nm to 3080 nm for solar, atmospheric and climatology physics. It is an external payload for the COLUMBUS laboratory launched on 7 February 2008. The mission’s primary objective is the measurement of the solar irradiance with the highest possible accuracy, and its variability using the following instruments: SOL-ACES (SOLar Auto-Calibrating EUV/UV Spectrophotometers) consists of four grazing incidence planar gratings measuring from 16 nm to 220 nm; SOLSPEC (SOLar SPECtrum) consists of three double gratings spectrometers, covering the range 165 nm to 3080 nm; and SOVIM (SOlar Variability Irradiance Monitor) is combining two types of absolute radiometers and three-channel filter - radiometers. SOLSPEC and SOL-ACES have been calibrated by primary standard radiation sources of the Physikalisch-Technische Bundesanstalt (PTB). Below we describe SOLSPEC, and its performance.

  12. Absolute quantitation of stevioside and rebaudioside A in commercial standards by quantitative NMR.

    PubMed

    Tada, Atsuko; Takahashi, Kana; Ishizuki, Kyoko; Sugimoto, Naoki; Suematsu, Takako; Arifuku, Kazunori; Tahara, Maiko; Akiyama, Takumi; Ito, Yusai; Yamazaki, Takeshi; Akiyama, Hiroshi; Kawamura, Yoko

    2013-01-01

    The extract prepared from the leaves of Stevia rebaudiana BERTONI (Asteraceae) contains sweet steviol glycosides, mainly stevioside and rebaudioside A. Highly purified stevia extracts have become popular worldwide as a natural, low-calorie sweetener. They contain various types of steviol glycosides, and their main components are stevioside and rebaudioside A. The content of each steviol glycoside is quantified by comparing the ratios of the molecular weights and the chromatographic peak areas of the samples to those of stevioside or rebaudioside A standards of the Food and Agriculture Organization of the United Nations (FAO)/World Health Organization (WHO) Joint Expert Committee on Food Additives (JECFA) and other specifications. However, various commercial standard reagents of stevioside and rebaudioside A are available. Their purities are different and their exact purities are not indicated. Therefore, the measured values of stevioside and rebaudioside A contained in a sample vary according to the standard used for the quantification. In this study, we utilized an accurate method, quantitative NMR (qNMR), for determining the contents of stevioside and rebaudioside A in standards, with traceability to the International System of Units (SI units). The purities of several commercial standards were determined to confirm their actual values.

  13. Internal quality control system for non-stationary, non-ergodic analytical processes based upon exponentially weighted estimation of process means and process standard deviation.

    PubMed

    Jansen, Rob T P; Laeven, Mark; Kardol, Wim

    2002-06-01

    The analytical processes in clinical laboratories should be considered to be non-stationary, non-ergodic and probably non-stochastic processes. Both the process mean and the process standard deviation vary. The variation can be different at different levels of concentration. This behavior is shown in five examples of different analytical systems: alkaline phosphatase on the Hitachi 911 analyzer (Roche), vitamin B12 on the Access analyzer (Beckman), prothrombin time and activated partial thromboplastin time on the STA Compact analyzer (Roche) and PO2 on the ABL 520 analyzer (Radiometer). A model is proposed to assess the status of a process. An exponentially weighted moving average and standard deviation was used to estimate process mean and standard deviation. Process means were estimated overall and for each control level. The process standard deviation was estimated in terms of within-run standard deviation. Limits were defined in accordance with state of the art- or biological variance-derived cut-offs. The examples given are real, not simulated, data. Individual control sample results were normalized to a target value and target standard deviation. The normalized values were used in the exponentially weighted algorithm. The weighting factor was based on a process time constant, which was estimated from the period between two calibration or maintenance procedures. The proposed system was compared with Westgard rules. The Westgard rules perform well, despite the underlying presumption of ergodicity. This is mainly caused by the introduction of the starting rule of 12s, which proves essential to prevent a large number of rule violations. The probability of reporting a test result with an analytical error that exceeds the total allowable error was calculated for the proposed system as well as for the Westgard rules. The proposed method performed better. The proposed algorithm was implemented in a computer program running on computers to which the analyzers were

  14. Absolute np and pp cross section determinations aimed at improving the standard for cross section measurements

    SciTech Connect

    Laptev, Alexander B; Haight, Robert C; Tovesson, Fredrik; Arndt, Richard A; Briscoe, William J; Paris, Mark W; Strakovsky, Igor I; Workman, Ron L

    2010-01-01

    Purpose of present research is a keeping improvement of the standard for cross section measurements of neutron-induced reactions. The cross sections for np and pp scattering below 1000 MeV are determined based on partial-wave analyses (PW As) of nucleon-nucleon scattering data. These cross sections are compared with the most recent ENDF/B-V11.0 and JENDL-4.0 data files, and the Nijmegen PWA. Also a comparison of evaluated data with recent experimental data was made to check a quality of evaluation. Excellent agreement was found between the new experimental data and our PWA predictions.

  15. Absolute np and pp Cross Section Determinations Aimed At Improving The Standard For Cross Section Measurements

    SciTech Connect

    Laptev, A. B.; Haight, R. C.; Tovesson, F.; Arndt, R. A.; Briscoe, W. J.; Paris, M. W.; Strakovsky, I. I.; Workman, R. L.

    2011-06-01

    Purpose of present research is a keeping improvement of the standard for cross section measurements of neutron-induced reactions. The cross sections for np and pp scattering below 1 GeV are determined based on partial-wave analyses (PWAs) of nucleon-nucleon scattering data. These cross sections are compared with the most recent ENDF/B-VII.0 and JENDL-4.0 data files, and the Nijmegen PWA. Also a comparison of evaluated data with recent experimental data was made to check a quality of evaluation. Excellent agreement was found between the new experimental data and our PWA predictions.

  16. Absolute standardization of 241Pu by the TDCR technique and effect of the beta spectral shape.

    PubMed

    van Wyngaardt, W M; Simpson, B R S; van Staden, M J; Lubbe, J

    2012-09-01

    The NMISA participated in the 2010 international key comparison of (241)Pu, standardizing the inter-comparison solution by the TDCR efficiency calculation technique. Special attention was paid to ensure accurate efficiency calculation for this low-energy, pure beta-emitter: in particular the effect of low-energy stopping powers on the calculation of ionization quenching was assessed and an optimal value for the quench parameter, kB, was determined. In addition, phototube efficiency mismatch was accounted for by a software minimization technique. The effect of the beta spectral shape on the activity extracted from data analysis was assessed and found to be significant. Based on the results of this work we propose a new value for the average beta-particle energy.

  17. Phase-resolved functional optical coherence tomography: simultaneous imaging of in situ tissue structure, blood flow velocity, standard deviation, birefringence, and Stokes vectors in human skin

    NASA Astrophysics Data System (ADS)

    Ren, Hongwu; Ding, Zhihua; Zhao, Yonghua; Miao, Jianjun; Nelson, J. Stuart; Chen, Zhongping

    2002-10-01

    We describe a phase-resolved functional optical coherence tomography system that can simultaneously yield in situ images of tissue structure, blood flow velocity, standard deviation, birefringence, and the Stokes vectors in human skin. Multifunctional images were obtained by processing of analytical interference fringe signals derived from two perpendicular polarization-detection channels. The blood flow velocity and standard deviation images were obtained by comparison of the phases from pairs of analytical signals in neighboring A-lines in the same polarization state. The analytical signals from two polarization-diversity detection channels were used to determine the four Stokes vectors for four reference polarization states. From the four Stokes vectors, the birefringence image, which is not sensitive to the orientation of the optical axis in the sample, was obtained. Multifunctional in situ images of a port wine stain birthmark in human skin are presented.

  18. Easy Absolute Values? Absolutely

    ERIC Educational Resources Information Center

    Taylor, Sharon E.; Mittag, Kathleen Cage

    2015-01-01

    The authors teach a problem-solving course for preservice middle-grades education majors that includes concepts dealing with absolute-value computations, equations, and inequalities. Many of these students like mathematics and plan to teach it, so they are adept at symbolic manipulations. Getting them to think differently about a concept that they…

  19. Simultaneous Determination of Absolute Configuration and Quantity of Lipopeptides Using Chiral Liquid Chromatography/Mass Spectrometry and Diastereomeric Internal Standards.

    PubMed

    Nemati, Reza; Dietz, Christopher; Anstadt, Emily; Clark, Robert; Smith, Michael; Nichols, Frank; Yao, Xudong

    2017-02-28

    Lipopeptides promote innate immune response and are related to disease pathology. To investigate the newly emerging roles of lipopeptides, accurate measurements of stereoisomers with multiple chiral centers are essential yet challenging. This work uses (3R)- and (3S)-(15-methyl-3-((13-methyltetradecanoyl)oxy)hexadecanoyl)glycyl-l-serine, abbreviated as l-serine-(R+S)-Lipid 654, to develop a method that combines chiral liquid chromatography, a diastereomeric mixture of isotopically labeled internal standards, and multiple reaction monitoring mass spectrometry. The new method allows for simultaneously determining the absolute configuration and quantity of stereoisomers of bacteria-derived lipopeptides. Total lipid extracts of nine evaluated bacteria strains had different amounts, but only the (R)-isoform of l-serine-Lipid 654. The developed method also allowed for the first quantitative analysis of hydrolysis of a nonphospholipid as a novel substrate of honey bee venom phospholipase A2.

  20. Absolute Quantitation of Glycosylation Site Occupancy Using Isotopically Labeled Standards and LC-MS

    NASA Astrophysics Data System (ADS)

    Zhu, Zhikai; Go, Eden P.; Desaire, Heather

    2014-06-01

    N-linked glycans are required to maintain appropriate biological functions on proteins. Underglycosylation leads to many diseases in plants and animals; therefore, characterizing the extent of glycosylation on proteins is an important step in understanding, diagnosing, and treating diseases. To determine the glycosylation site occupancy, protein N-glycosidase F (PNGase F) is typically used to detach the glycan from the protein, during which the formerly glycosylated asparagine undergoes deamidation to become an aspartic acid. By comparing the abundance of the resulting peptide containing aspartic acid against the one containing non-glycosylated asparagine, the glycosylation site occupancy can be evaluated. However, this approach can give inaccurate results when spontaneous chemical deamidation of the non-glycosylated asparagine occurs. To overcome this limitation, we developed a new method to measure the glycosylation site occupancy that does not rely on converting glycosylated peptides to their deglycosylated forms. Specifically, the overall protein concentration and the non-glycosylated portion of the protein are quantified simultaneously by using heavy isotope-labeled internal standards coupled with LC-MS analysis, and the extent of site occupancy is accurately determined. The efficacy of the method was demonstrated by quantifying the occupancy of a glycosylation site on bovine fetuin. The developed method is the first work that measures the glycosylation site occupancy without using PNGase F, and it can be done in parallel with glycopeptide analysis because the glycan remains intact throughout the workflow.

  1. Accurate Quantification of Cardiovascular Biomarkers in Serum Using Protein Standard Absolute Quantification (PSAQ™) and Selected Reaction Monitoring*

    PubMed Central

    Huillet, Céline; Adrait, Annie; Lebert, Dorothée; Picard, Guillaume; Trauchessec, Mathieu; Louwagie, Mathilde; Dupuis, Alain; Hittinger, Luc; Ghaleh, Bijan; Le Corvoisier, Philippe; Jaquinod, Michel; Garin, Jérôme; Bruley, Christophe; Brun, Virginie

    2012-01-01

    Development of new biomarkers needs to be significantly accelerated to improve diagnostic, prognostic, and toxicity monitoring as well as therapeutic follow-up. Biomarker evaluation is the main bottleneck in this development process. Selected Reaction Monitoring (SRM) combined with stable isotope dilution has emerged as a promising option to speed this step, particularly because of its multiplexing capacities. However, analytical variabilities because of upstream sample handling or incomplete trypsin digestion still need to be resolved. In 2007, we developed the PSAQ™ method (Protein Standard Absolute Quantification), which uses full-length isotope-labeled protein standards to quantify target proteins. In the present study we used clinically validated cardiovascular biomarkers (LDH-B, CKMB, myoglobin, and troponin I) to demonstrate that the combination of PSAQ and SRM (PSAQ-SRM) allows highly accurate biomarker quantification in serum samples. A multiplex PSAQ-SRM assay was used to quantify these biomarkers in clinical samples from myocardial infarction patients. Good correlation between PSAQ-SRM and ELISA assay results was found and demonstrated the consistency between these analytical approaches. Thus, PSAQ-SRM has the capacity to improve both accuracy and reproducibility in protein analysis. This will be a major contribution to efficient biomarker development strategies. PMID:22080464

  2. ABSOLUTE FLUX CALIBRATION OF THE IRAC INSTRUMENT ON THE SPITZER SPACE TELESCOPE USING HUBBLE SPACE TELESCOPE FLUX STANDARDS

    SciTech Connect

    Bohlin, R. C.; Gordon, K. D.; Deustua, S.; Ferguson, H. C.; Flanagan, K.; Kalirai, J.; Meixner, M.; Rieke, G. H.; Engelbracht, C.; Su, K. Y. L.; Ardila, D.; Tremblay, P.-E.

    2011-05-15

    The absolute flux calibration of the James Webb Space Telescope (JWST) will be based on a set of stars observed by the Hubble and Spitzer Space Telescopes. In order to cross-calibrate the two facilities, several A, G, and white dwarf stars are observed with both Spitzer and Hubble and are the prototypes for a set of JWST calibration standards. The flux calibration constants for the four Spitzer IRAC bands 1-4 are derived from these stars and are 2.3%, 1.9%, 2.0%, and 0.5% lower than the official cold-mission IRAC calibration of Reach et al., i.e., in agreement within their estimated errors of {approx}2%. The causes of these differences lie primarily in the IRAC data reduction and secondarily in the spectral energy distributions of our standard stars. The independent IRAC 8 {mu}m band-4 fluxes of Rieke et al. are about 1.5% {+-} 2% higher than those of Reach et al. and are also in agreement with our 8 {mu}m result.

  3. Absolute binding-free energies between standard RNA/DNA nucleobases and amino-acid sidechain analogs in different environments.

    PubMed

    de Ruiter, Anita; Zagrovic, Bojan

    2015-01-01

    Despite the great importance of nucleic acid-protein interactions in the cell, our understanding of their physico-chemical basis remains incomplete. In order to address this challenge, we have for the first time determined potentials of mean force and the associated absolute binding free energies between all standard RNA/DNA nucleobases and amino-acid sidechain analogs in high- and low-dielectric environments using molecular dynamics simulations and umbrella sampling. A comparison against a limited set of available experimental values for analogous systems attests to the quality of the computational approach and the force field used. Overall, our analysis provides a microscopic picture behind nucleobase/sidechain interaction preferences and creates a unified framework for understanding and sculpting nucleic acid-protein interactions in different contexts. Here, we use this framework to demonstrate a strong relationship between nucleobase density profiles of mRNAs and nucleobase affinity profiles of their cognate proteins and critically analyze a recent hypothesis that the two may be capable of direct, complementary interactions.

  4. Accurate absolute GPS positioning through satellite clock error estimation

    NASA Astrophysics Data System (ADS)

    Han, S.-C.; Kwon, J. H.; Jekeli, C.

    2001-05-01

    An algorithm for very accurate absolute positioning through Global Positioning System (GPS) satellite clock estimation has been developed. Using International GPS Service (IGS) precise orbits and measurements, GPS clock errors were estimated at 30-s intervals. Compared to values determined by the Jet Propulsion Laboratory, the agreement was at the level of about 0.1 ns (3 cm). The clock error estimates were then applied to an absolute positioning algorithm in both static and kinematic modes. For the static case, an IGS station was selected and the coordinates were estimated every 30 s. The estimated absolute position coordinates and the known values had a mean difference of up to 18 cm with standard deviation less than 2 cm. For the kinematic case, data obtained every second from a GPS buoy were tested and the result from the absolute positioning was compared to a differential GPS (DGPS) solution. The mean differences between the coordinates estimated by the two methods are less than 40 cm and the standard deviations are less than 25 cm. It was verified that this poorer standard deviation on 1-s position results is due to the clock error interpolation from 30-s estimates with Selective Availability (SA). After SA was turned off, higher-rate clock error estimates (such as 1 s) could be obtained by a simple interpolation with negligible corruption. Therefore, the proposed absolute positioning technique can be used to within a few centimeters' precision at any rate by estimating 30-s satellite clock errors and interpolating them.

  5. Properties of pattern standard deviation in open-angle glaucoma patients with hemi-optic neuropathy and bi-optic neuropathy

    PubMed Central

    Heo, Dong Won; Kim, Kyoung Nam; Lee, Min Woo; Lee, Sung Bok; Kim, Chang-sik

    2017-01-01

    Purpose To evaluate the properties of pattern standard deviation (PSD) according to localization of the glaucomatous optic neuropathy. Methods We enrolled 242 eyes of 242 patients with primary open-angle glaucoma, with a best-corrected visual acuity ≥ 20/25, and no media opacity. Patients were examined via dilated fundus photography, spectral-domain optical coherence tomography, and Humphrey visual field examination, and divided into those with hemi-optic neuropathy (superior or inferior) and bi-optic neuropathy (both superior and inferior). We assessed the relationship between mean deviation (MD) and PSD. Using broken stick regression analysis, the tipping point was identified, i.e., the point at which MD became significantly associated with a paradoxical reversal of PSD. Results In 91 patients with hemi-optic neuropathy, PSD showed a strong correlation with MD (r = −0.973, β = −0.965, p < 0.001). The difference between MD and PSD (“−MD−PSD”) was constant (mean, −0.32 dB; 95% confidence interval, −2.48~1.84 dB) regardless of visual field defect severity. However, in 151 patients with bi-optic neuropathy, a negative correlation was evident between “−MD−PSD” and MD (r2 = 0.907, p < 0.001). Overall, the MD tipping point was −14.0 dB, which was close to approximately 50% damage of the entire visual field (p < 0.001). Conclusions Although a false decrease of PSD usually begins at approximately 50% visual field damage, in patients with hemi-optic neuropathy, the PSD shows no paradoxical decrease and shows a linear correlation with MD. PMID:28249022

  6. Absolute elastic differential electron scattering cross sections for He - A proposed calibration standard from 5 to 200 eV

    NASA Technical Reports Server (NTRS)

    Register, D. F.; Trajmar, S.; Srivastava, S. K.

    1980-01-01

    Absolute differential, integral, and momentum-transfer cross sections for electrons elastically scattered from helium are reported for the impact energy range of 5 to 200 eV. Angular distributions for elastically scattered electrons are measured in a crossed-beam geometry using a collimated, differentially pumped atomic-beam source which requires no effective-path-length correction. Below the first inelastic threshold the angular distributions were placed on an absolute scale by use of a phase-shift analysis. Above this threshold, the angular distributions from 10 to 140 deg were fitted using the phase-shift technique, and the resulting integral cross sections were normalized to a semiempirically derived integral elastic cross section. Depending on the impact energy, the data are estimated to be accurate to within 5 to 9%.

  7. (18)F primary standard at ENEA-INMRI by three absolute techniques and calibration of a well-type IG11 ionization chamber.

    PubMed

    Capogni, Marco; Carconi, Pierluigi; De Felice, Pierino; Fazio, Aldo

    2016-03-01

    A new (18)F primary standardization carried out at ENEA-INMRI by three different absolute techniques, i.e. 4πγNaI(Tl)γ high-efficiency counting, TDCR and 4πβ(LS)-γ[NaI(Tl)] coincidence counting method, allowed the calibration of a fixed well-reentrant IG11 ionization chamber (IC), with an uncertainty lower than 1%, and to check the calibration factor of a portable well-type IC NPL-CRC model, previously calibrated. By the new standard the ENEA-INMRI was linked to the BIPM International Reference System (SIR) through the BIPM SIR Transfer Instrument (SIRTI).

  8. Development of defined microbial population standards using fluorescence activated cell sorting for the absolute quantification of S. aureus using real-time PCR.

    PubMed

    Martinon, Alice; Cronin, Ultan P; Wilkinson, Martin G

    2012-01-01

    In this article, four types of standards were assessed in a SYBR Green-based real-time PCR procedure for the quantification of Staphylococcus aureus (S. aureus) in DNA samples. The standards were purified S. aureus genomic DNA (type A), circular plasmid DNA containing a thermonuclease (nuc) gene fragment (type B), DNA extracted from defined populations of S. aureus cells generated by Fluorescence Activated Cell Sorting (FACS) technology with (type C) or without purification of DNA by boiling (type D). The optimal efficiency of 2.016 was obtained on Roche LightCycler(®) 4.1. software for type C standards, whereas the lowest efficiency (1.682) corresponded to type D standards. Type C standards appeared to be more suitable for quantitative real-time PCR because of the use of defined populations for construction of standard curves. Overall, Fieller Confidence Interval algorithm may be improved for replicates having a low standard deviation in Cycle Threshold values such as found for type B and C standards. Stabilities of diluted PCR standards stored at -20°C were compared after 0, 7, 14 and 30 days and were lower for type A or C standards compared with type B standards. However, FACS generated standards may be useful for bacterial quantification in real-time PCR assays once optimal storage and temperature conditions are defined.

  9. Novel isotopic N, N-Dimethyl Leucine (iDiLeu) Reagents Enable Absolute Quantification of Peptides and Proteins Using a Standard Curve Approach

    NASA Astrophysics Data System (ADS)

    Greer, Tyler; Lietz, Christopher B.; Xiang, Feng; Li, Lingjun

    2015-01-01

    Absolute quantification of protein targets using liquid chromatography-mass spectrometry (LC-MS) is a key component of candidate biomarker validation. One popular method combines multiple reaction monitoring (MRM) using a triple quadrupole instrument with stable isotope-labeled standards (SIS) for absolute quantification (AQUA). LC-MRM AQUA assays are sensitive and specific, but they are also expensive because of the cost of synthesizing stable isotope peptide standards. While the chemical modification approach using mass differential tags for relative and absolute quantification (mTRAQ) represents a more economical approach when quantifying large numbers of peptides, these reagents are costly and still suffer from lower throughput because only two concentration values per peptide can be obtained in a single LC-MS run. Here, we have developed and applied a set of five novel mass difference reagents, isotopic N, N-dimethyl leucine (iDiLeu). These labels contain an amine reactive group, triazine ester, are cost effective because of their synthetic simplicity, and have increased throughput compared with previous LC-MS quantification methods by allowing construction of a four-point standard curve in one run. iDiLeu-labeled peptides show remarkably similar retention time shifts, slightly lower energy thresholds for higher-energy collisional dissociation (HCD) fragmentation, and high quantification accuracy for trypsin-digested protein samples (median errors <15%). By spiking in an iDiLeu-labeled neuropeptide, allatostatin, into mouse urine matrix, two quantification methods are validated. The first uses one labeled peptide as an internal standard to normalize labeled peptide peak areas across runs (<19% error), whereas the second enables standard curve creation and analyte quantification in one run (<8% error).

  10. Autocorrelation standard deviation and root mean square frequency analysis of polymer electrolyte membrane fuel cell to monitor for hydrogen and air undersupply

    NASA Astrophysics Data System (ADS)

    Kim, Joo Gon; Mukherjee, Santanu; Bates, Alex; Zickel, Benjamin; Park, Sam; Son, Byung Rak; Choi, Jae Sung; Kwon, Osung; Lee, Dong Ha; Chung, Hyun-Youl

    2015-12-01

    Proton exchange membrane fuel cells are a promising energy conversion device which can help to solve urgent environmental and economic problems. Among the various types of fuel cells, the air breathing proton exchange membrane fuel cell, which minimizes the balance of plant, has drawn a lot of attention due to its superior energy density. In this study a compact, air breathing, proton exchange membrane fuel cell based on Nafion and a Pt/C membrane electrode assembly was designed. The fuel cell was tested using a Scribner Associates 850e fuel cell test station. Specifically, the hydrogen fuel and oxygen starvation of the fuel cell were accurately and systematically tested and analyzed using a frequency analysis method which can analyze the input and output frequency. The analysis of the frequency variation under a fuel starvation condition was done using RMSF (root mean square frequency) and ACSD (autocorrelation standard deviation). The study reveals two significant results: first, the fuel starvations show entirely different phenomenon in both RMSF and ACSD and second, the results of the Autocorrelation show clearer results for fuel starvation detection than the results with RMSF.

  11. Absolute Frequency Measurements with a Set of Transportable HE-NE/CH4 Optical Frequency Standards and Prospects for Future Design and Applications

    NASA Astrophysics Data System (ADS)

    Gubin, M.; Kovalchuk, E.; Petrukhin, E.; Shelkovnikov, A.; Tyurikov, D.; Gamidov, R.; Erdogan, C.; Sahin, E.; Felder, R.; Gill, P.; Lea, S. N.; Kramer, G.; Lipphardt, B.

    2002-04-01

    The accumulated results of absolute frequency measurements (AFM) carried out in 1997-2000 with transportable double-mode He-Ne/CH4 optical frequency standards (λ = 3 .39μm) in a collaboration of several laboratories are presented. The performance of this secondary optical frequency standard is estimated on the level of 10-13 (in repeatability), and 1 × 10-14/s (in stability). The next steps towards He-Ne/CH4 standards with one order of magnitude better performance, including devices based on monolithic zerodur resonators, are discussed. Important applications of transportable He-Ne/CH4 optical frequency standards have appeared now due to dramatic progress in the field of optical frequency measurements. Used to stabilize the repetition rate of a Ti:Sa fs laser, these compact secondary standards can transfer their performance into the whole optical range covered by a fs comb. Thus they can play the role of a narrow spectrum interrogative oscillator for super-accurate optical or microwave frequency standards substituting in some tasks a H-maser or oscillators based on cryogenic sapphire resonators.

  12. Chemo-Enzymatic Synthesis of (13)C Labeled Complex N-Glycans As Internal Standards for the Absolute Glycan Quantification by Mass Spectrometry.

    PubMed

    Echeverria, Begoña; Etxebarria, Juan; Ruiz, Nerea; Hernandez, Álvaro; Calvo, Javier; Haberger, Markus; Reusch, Dietmar; Reichardt, Niels-Christian

    2015-11-17

    Methods for the absolute quantification of glycans are needed in glycoproteomics, during development and production of biopharmaceuticals and for the clinical analysis of glycan disease markers. Here we present a strategy for the chemo-enzymatic synthesis of (13)C labeled N-glycan libraries and provide an example for their use as internal standards in the profiling and absolute quantification of mAb glycans by matrix-assisted laser desorption ionization-time-of-flight (MALDI-TOF) mass spectrometry. A synthetic biantennary glycan precursor was (13)C-labeled on all four amino sugar residues and enzymatically derivatized to produce a library of 15 glycan isotopologues with a mass increment of 8 Da over the natural products. Asymmetrically elongated glycans were accessible by performing enzymatic reactions on partially protected UV-absorbing intermediates, subsequent fractionation by preparative HPLC, and final hydrogenation. Using a preformulated mixture of eight internal standards, we quantified the glycans in a monoclonal therapeutic antibody with excellent precision and speed.

  13. Development of a low-level 39Ar calibration standard – Analysis by absolute gas counting measurements augmented with simulation

    DOE PAGES

    Williams, Richard M.; Aalseth, C. E.; Brandenberger, J. M.; ...

    2017-02-17

    Here, this paper describes the generation of 39Ar, via reactor irradiation of potassium carbonate, followed by quantitative analysis (length-compensated proportional counting) to yield two calibration standards that are respectively 50 and 3 times atmospheric background levels. Measurements were performed in Pacific Northwest National Laboratory's shallow underground counting laboratory studying the effect of gas density on beta-transport; these results are compared with simulation. The total expanded uncertainty of the specific activity for the ~50 × 39Ar in P10 standard is 3.6% (k=2).

  14. Application of the standard addition method for the absolute quantification of neutral lipids in microalgae using Nile red.

    PubMed

    Bertozzini, Elena; Galluzzi, Luca; Penna, Antonella; Magnani, Mauro

    2011-10-01

    Microalgae are considered one of the best candidates for biofuel production due to their high content in neutral lipids, therefore, an accurate quantification of these lipids in microalgae is fundamental for the identification of the better candidates as biodiesel source. Nile red is a fluorescent dye widely employed for the quantification of neutral lipids in microalgae. Usually, the fluorescence intensity of the stained samples is correlated to the neutral lipid content determined with standard methods, in order to draw a standard curve and deduce the neutral lipids concentration of the unknown samples positioning their fluorescence intensity values on the curve. Standard methods used for the neutral lipids determination are laborious and often implying solvent extraction and/or other transformation (i.e. saponification or transesterification) of the sample. These methods are also time consuming and may give rise to an underestimation of the lipid content due to variable extraction yields. The approach described in this paper combines the standard addition method and the fluorometric staining using Nile red, avoiding the association of traditional neutral lipids quantification methods to the fluorometric determination. After optimization of instrument parameters and staining conditions, a linear correlation between the fluorescence intensity of each sample stained with the Nile red and its neutral lipids content deduced with the standard addition method was identified. The obtained curve allowed the direct determination of neutral lipids content maintaining a linearity range from 0.12 to 12 μg of neutral lipids per ml of sample, without need of pre-concentration. This curve was then used in the quantification of the neutral lipids content in culture of Skeletonema marinoi (Bacillariophyceae) at different days from the inoculum. This method was also successfully applied on Chaetoceros socialis (Bacillariophyceae) and Alexandrium minutum (Dinophyceae).

  15. Absolute Zero

    NASA Astrophysics Data System (ADS)

    Donnelly, Russell J.; Sheibley, D.; Belloni, M.; Stamper-Kurn, D.; Vinen, W. F.

    2006-12-01

    Absolute Zero is a two hour PBS special attempting to bring to the general public some of the advances made in 400 years of thermodynamics. It is based on the book “Absolute Zero and the Conquest of Cold” by Tom Shachtman. Absolute Zero will call long-overdue attention to the remarkable strides that have been made in low-temperature physics, a field that has produced 27 Nobel Prizes. It will explore the ongoing interplay between science and technology through historical examples including refrigerators, ice machines, frozen foods, liquid oxygen and nitrogen as well as much colder fluids such as liquid hydrogen and liquid helium. A website has been established to promote the series: www.absolutezerocampaign.org. It contains information on the series, aimed primarily at students at the middle school level. There is a wealth of material here and we hope interested teachers will draw their student’s attention to this website and its substantial contents, which have been carefully vetted for accuracy.

  16. 10 CFR 961.4 - Deviations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Deviations. 961.4 Section 961.4 Energy DEPARTMENT OF ENERGY STANDARD CONTRACT FOR DISPOSAL OF SPENT NUCLEAR FUEL AND/OR HIGH-LEVEL RADIOACTIVE WASTE General § 961.4 Deviations. Requests for authority to deviate from this part shall be submitted in writing...

  17. 10 CFR 961.4 - Deviations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Deviations. 961.4 Section 961.4 Energy DEPARTMENT OF ENERGY STANDARD CONTRACT FOR DISPOSAL OF SPENT NUCLEAR FUEL AND/OR HIGH-LEVEL RADIOACTIVE WASTE General § 961.4 Deviations. Requests for authority to deviate from this part shall be submitted in writing...

  18. 10 CFR 961.4 - Deviations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Deviations. 961.4 Section 961.4 Energy DEPARTMENT OF ENERGY STANDARD CONTRACT FOR DISPOSAL OF SPENT NUCLEAR FUEL AND/OR HIGH-LEVEL RADIOACTIVE WASTE General § 961.4 Deviations. Requests for authority to deviate from this part shall be submitted in writing...

  19. 10 CFR 961.4 - Deviations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Deviations. 961.4 Section 961.4 Energy DEPARTMENT OF ENERGY STANDARD CONTRACT FOR DISPOSAL OF SPENT NUCLEAR FUEL AND/OR HIGH-LEVEL RADIOACTIVE WASTE General § 961.4 Deviations. Requests for authority to deviate from this part shall be submitted in writing...

  20. 10 CFR 961.4 - Deviations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Deviations. 961.4 Section 961.4 Energy DEPARTMENT OF ENERGY STANDARD CONTRACT FOR DISPOSAL OF SPENT NUCLEAR FUEL AND/OR HIGH-LEVEL RADIOACTIVE WASTE General § 961.4 Deviations. Requests for authority to deviate from this part shall be submitted in writing...

  1. Absolute neutrino mass scale

    NASA Astrophysics Data System (ADS)

    Capelli, Silvia; Di Bari, Pasquale

    2013-04-01

    Neutrino oscillation experiments firmly established non-vanishing neutrino masses, a result that can be regarded as a strong motivation to extend the Standard Model. In spite of being the lightest massive particles, neutrinos likely represent an important bridge to new physics at very high energies and offer new opportunities to address some of the current cosmological puzzles, such as the matter-antimatter asymmetry of the Universe and Dark Matter. In this context, the determination of the absolute neutrino mass scale is a key issue within modern High Energy Physics. The talks in this parallel session well describe the current exciting experimental activity aiming to determining the absolute neutrino mass scale and offer an overview of a few models beyond the Standard Model that have been proposed in order to explain the neutrino masses giving a prediction for the absolute neutrino mass scale and solving the cosmological puzzles.

  2. Absolute Summ

    NASA Astrophysics Data System (ADS)

    Phillips, Alfred, Jr.

    Summ means the entirety of the multiverse. It seems clear, from the inflation theories of A. Guth and others, that the creation of many universes is plausible. We argue that Absolute cosmological ideas, not unlike those of I. Newton, may be consistent with dynamic multiverse creations. As suggested in W. Heisenberg's uncertainty principle, and with the Anthropic Principle defended by S. Hawking, et al., human consciousness, buttressed by findings of neuroscience, may have to be considered in our models. Predictability, as A. Einstein realized with Invariants and General Relativity, may be required for new ideas to be part of physics. We present here a two postulate model geared to an Absolute Summ. The seedbed of this work is part of Akhnaton's philosophy (see S. Freud, Moses and Monotheism). Most important, however, is that the structure of human consciousness, manifest in Kenya's Rift Valley 200,000 years ago as Homo sapiens, who were the culmination of the six million year co-creation process of Hominins and Nature in Africa, allows us to do the physics that we do. .

  3. Absolute Photometry

    NASA Astrophysics Data System (ADS)

    Hartig, George

    1990-12-01

    The absolute sensitivity of the FOS will be determined in SV by observing 2 stars at 3 epochs, first in 3 apertures (1.0", 0.5", and 0.3" circular) and then in 1 aperture (1.0" circular). In cycle 1, one star, BD+28D4211 will be observed in the 1.0" aperture to establish the stability of the sensitivity and flat field characteristics and improve the accuracy obtained in SV. This star will also be observed through the paired apertures since these are not calibrated in SV. The stars will be observed in most detector/grating combinations. The data will be averaged to form the inverse sensitivity functions required by RSDP.

  4. Electronic Absolute Cartesian Autocollimator

    NASA Technical Reports Server (NTRS)

    Leviton, Douglas B.

    2006-01-01

    An electronic absolute Cartesian autocollimator performs the same basic optical function as does a conventional all-optical or a conventional electronic autocollimator but differs in the nature of its optical target and the manner in which the position of the image of the target is measured. The term absolute in the name of this apparatus reflects the nature of the position measurement, which, unlike in a conventional electronic autocollimator, is based absolutely on the position of the image rather than on an assumed proportionality between the position and the levels of processed analog electronic signals. The term Cartesian in the name of this apparatus reflects the nature of its optical target. Figure 1 depicts the electronic functional blocks of an electronic absolute Cartesian autocollimator along with its basic optical layout, which is the same as that of a conventional autocollimator. Referring first to the optical layout and functions only, this or any autocollimator is used to measure the compound angular deviation of a flat datum mirror with respect to the optical axis of the autocollimator itself. The optical components include an illuminated target, a beam splitter, an objective or collimating lens, and a viewer or detector (described in more detail below) at a viewing plane. The target and the viewing planes are focal planes of the lens. Target light reflected by the datum mirror is imaged on the viewing plane at unit magnification by the collimating lens. If the normal to the datum mirror is parallel to the optical axis of the autocollimator, then the target image is centered on the viewing plane. Any angular deviation of the normal from the optical axis manifests itself as a lateral displacement of the target image from the center. The magnitude of the displacement is proportional to the focal length and to the magnitude (assumed to be small) of the angular deviation. The direction of the displacement is perpendicular to the axis about which the

  5. Contributed Review: Absolute spectral radiance calibration of fiber-optic shock-temperature pyrometers using a coiled-coil irradiance standard lamp

    NASA Astrophysics Data System (ADS)

    Fat'yanov, O. V.; Asimow, P. D.

    2015-10-01

    We describe an accurate and precise calibration procedure for multichannel optical pyrometers such as the 6-channel, 3-ns temporal resolution instrument used in the Caltech experimental geophysics laboratory. We begin with a review of calibration sources for shock temperatures in the 3000-30 000 K range. High-power, coiled tungsten halogen standards of spectral irradiance appear to be the only practical alternative to NIST-traceable tungsten ribbon lamps, which are no longer available with large enough calibrated area. However, non-uniform radiance complicates the use of such coiled lamps for reliable and reproducible calibration of pyrometers that employ imaging or relay optics. Careful analysis of documented methods of shock pyrometer calibration to coiled irradiance standard lamps shows that only one technique, not directly applicable in our case, is free of major radiometric errors. We provide a detailed description of the modified Caltech pyrometer instrument and a procedure for its absolute spectral radiance calibration, accurate to ±5%. We employ a designated central area of a 0.7× demagnified image of a coiled-coil tungsten halogen lamp filament, cross-calibrated against a NIST-traceable tungsten ribbon lamp. We give the results of the cross-calibration along with descriptions of the optical arrangement, data acquisition, and processing. We describe a procedure to characterize the difference between the static and dynamic response of amplified photodetectors, allowing time-dependent photodiode correction factors for spectral radiance histories from shock experiments. We validate correct operation of the modified Caltech pyrometer with actual shock temperature experiments on single-crystal NaCl and MgO and obtain very good agreement with the literature data for these substances. We conclude with a summary of the most essential requirements for error-free calibration of a fiber-optic shock-temperature pyrometer using a high-power coiled tungsten halogen

  6. Contributed Review: Absolute spectral radiance calibration of fiber-optic shock-temperature pyrometers using a coiled-coil irradiance standard lamp

    SciTech Connect

    Fat’yanov, O. V. Asimow, P. D.

    2015-10-15

    We describe an accurate and precise calibration procedure for multichannel optical pyrometers such as the 6-channel, 3-ns temporal resolution instrument used in the Caltech experimental geophysics laboratory. We begin with a review of calibration sources for shock temperatures in the 3000-30 000 K range. High-power, coiled tungsten halogen standards of spectral irradiance appear to be the only practical alternative to NIST-traceable tungsten ribbon lamps, which are no longer available with large enough calibrated area. However, non-uniform radiance complicates the use of such coiled lamps for reliable and reproducible calibration of pyrometers that employ imaging or relay optics. Careful analysis of documented methods of shock pyrometer calibration to coiled irradiance standard lamps shows that only one technique, not directly applicable in our case, is free of major radiometric errors. We provide a detailed description of the modified Caltech pyrometer instrument and a procedure for its absolute spectral radiance calibration, accurate to ±5%. We employ a designated central area of a 0.7× demagnified image of a coiled-coil tungsten halogen lamp filament, cross-calibrated against a NIST-traceable tungsten ribbon lamp. We give the results of the cross-calibration along with descriptions of the optical arrangement, data acquisition, and processing. We describe a procedure to characterize the difference between the static and dynamic response of amplified photodetectors, allowing time-dependent photodiode correction factors for spectral radiance histories from shock experiments. We validate correct operation of the modified Caltech pyrometer with actual shock temperature experiments on single-crystal NaCl and MgO and obtain very good agreement with the literature data for these substances. We conclude with a summary of the most essential requirements for error-free calibration of a fiber-optic shock-temperature pyrometer using a high-power coiled tungsten halogen

  7. Database applicaton for absolute spectrophotometry

    NASA Astrophysics Data System (ADS)

    Bochkov, Valery V.; Shumko, Sergiy

    2002-12-01

    32-bit database application with multidocument interface for Windows has been developed to calculate absolute energy distributions of observed spectra. The original database contains wavelength calibrated observed spectra which had been already passed through apparatus reductions such as flatfielding, background and apparatus noise subtracting. Absolute energy distributions of observed spectra are defined in unique scale by means of registering them simultaneously with artificial intensity standard. Observations of sequence of spectrophotometric standards are used to define absolute energy of the artificial standard. Observations of spectrophotometric standards are used to define optical extinction in selected moments. FFT algorithm implemented in the application allows performing convolution (deconvolution) spectra with user-defined PSF. The object-oriented interface has been created using facilities of C++ libraries. Client/server model with Windows Socket functionality based on TCP/IP protocol is used to develop the application. It supports Dynamic Data Exchange conversation in server mode and uses Microsoft Exchange communication facilities.

  8. Caudal septal deviation.

    PubMed

    Haack, Jason; Papel, Ira D

    2009-06-01

    The nasal septum is a structure poorly understood and appreciated by the lay public and the nonotolaryngologist--head and neck surgeon alike. Deviation of the caudal portion of the nasal septum may result in nasal obstruction, a crooked nose, and columellar irregularities. The correction of a severely deviated caudal septum is one of the most difficult challenges of the otolaryngologist and facial plastic surgeon. A variety of options are available for correction of mild, to the most severe, deflections. This condition, as with all challenges in medicine, should not be a one size fits all or one surgery fits all situation. The skilled surgeon should understand the multiple options available for surgical correction and tailor fit the procedure to the deformity.

  9. Analyzing Vehicle Operator Deviations

    DTIC Science & Technology

    2008-07-01

    related to vehicle operator deviations ( VODs ). VODs occur when a vehicle enters the airport movement area without ATC approval. We developed a VOD ...prediction model to help understand the human factors causes associated with different types of VODs . We then examined the validity of the model, using...the data that we needed was missing due to incomplete reporting of the human factors associated with a given VOD . To aid in the development of a

  10. Final report on EURAMET.M.P-K4.2010: Key and supplementary comparison of national pressure standards in the range 1 Pa to 15 kPa of absolute and gauge pressure

    NASA Astrophysics Data System (ADS)

    Krajíček, Zdeněk; Bergoglio, Mercede; Jousten, Karl; Otal, Pierre; Sabuga, Wladimir; Saxholm, Sari; Pražák, Dominik; Vičar, Martin

    2014-01-01

    This report describes a EURAMET comparison of five European National Metrology Institutes in low gauge and absolute pressure in gas (nitrogen), denoted as EURAMET.M.P-K4.2010. Its main intention is to state equivalence of the pressure standards, in particular those based on the technology of force-balanced piston gauges such as e.g. FRS by Furness Controls, UK and FPG8601 by DHI-Fluke, USA. It covers the range from 1 Pa to 15 kPa, both gauge and absolute. The comparison in absolute mode serves as a EURAMET Key Comparison which can be linked to CCM.P-K4 and CCM.P-K2 via PTB. The comparison in gauge mode is a supplementary comparison. The comparison was carried out from September 2008 till October 2012. The participating laboratories were the following: CMI, INRIM, LNE, MIKES, PTB-Berlin (absolute pressure 1 kPa and below) and PTB-Braunschweig (absolute pressure 1 kPa and above and gauge pressure). CMI was the pilot laboratory and provided a transfer standard for the comparison. This transfer standard was also the laboratory standard of CMI at the same time, which resulted in a unique and logistically difficult star comparison. Both in gauge and absolute pressures all the participating institutes successfully proved their equivalence with respect to the reference value and all also proved mutual bilateral equivalences in all the points. All the participating laboratories are also equivalent with the reference values of CCM.P-K4 and CCM.P-K2 in the relevant points. The comparison also proved the ability of FPG8601 to serve as a transfer standard. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  11. Dataset on the mean, standard deviation, broad-sense heritability and stability of wheat quality bred in three different ways and grown under organic and low-input conventional systems

    PubMed Central

    Rakszegi, Marianna; Löschenberger, Franziska; Hiltbrunner, Jürg; Vida, Gyula; Mikó, Péter

    2016-01-01

    An assessment was previously made of the effects of organic and low-input field management systems on the physical, grain compositional and processing quality of wheat and on the performance of varieties developed using different breeding methods (“Comparison of quality parameters of wheat varieties with different breeding origin under organic and low-input conventional conditions” [1]). Here, accompanying data are provided on the performance and stability analysis of the genotypes using the coefficient of variation and the ‘ranking’ and ‘which-won-where’ plots of GGE biplot analysis for the most important quality traits. Broad-sense heritability was also evaluated and is given for the most important physical and quality properties of the seed in organic and low-input management systems, while mean values and standard deviation of the studied properties are presented separately for organic and low-input fields. PMID:27222865

  12. Dataset on the mean, standard deviation, broad-sense heritability and stability of wheat quality bred in three different ways and grown under organic and low-input conventional systems.

    PubMed

    Rakszegi, Marianna; Löschenberger, Franziska; Hiltbrunner, Jürg; Vida, Gyula; Mikó, Péter

    2016-06-01

    An assessment was previously made of the effects of organic and low-input field management systems on the physical, grain compositional and processing quality of wheat and on the performance of varieties developed using different breeding methods ("Comparison of quality parameters of wheat varieties with different breeding origin under organic and low-input conventional conditions" [1]). Here, accompanying data are provided on the performance and stability analysis of the genotypes using the coefficient of variation and the 'ranking' and 'which-won-where' plots of GGE biplot analysis for the most important quality traits. Broad-sense heritability was also evaluated and is given for the most important physical and quality properties of the seed in organic and low-input management systems, while mean values and standard deviation of the studied properties are presented separately for organic and low-input fields.

  13. Linear versus non-linear measures of temporal variability in finger tapping and their relation to performance on open- versus closed-loop motor tasks: comparing standard deviations to Lyapunov exponents.

    PubMed

    Christman, Stephen D; Weaver, Ryan

    2008-05-01

    The nature of temporal variability during speeded finger tapping was examined using linear (standard deviation) and non-linear (Lyapunov exponent) measures. Experiment 1 found that right hand tapping was characterised by lower amounts of both linear and non-linear measures of variability than left hand tapping, and that linear and non-linear measures of variability were often negatively correlated with one another. Experiment 2 found that increased non-linear variability was associated with relatively enhanced performance on a closed-loop motor task (mirror tracing) and relatively impaired performance on an open-loop motor task (pointing in a dark room), especially for left hand performance. The potential uses and significance of measures of non-linear variability are discussed.

  14. Teaching Absolute Value Meaningfully

    ERIC Educational Resources Information Center

    Wade, Angela

    2012-01-01

    What is the meaning of absolute value? And why do teachers teach students how to solve absolute value equations? Absolute value is a concept introduced in first-year algebra and then reinforced in later courses. Various authors have suggested instructional methods for teaching absolute value to high school students (Wei 2005; Stallings-Roberts…

  15. Absolute rate of the reaction of hydrogen atoms with ozone from 219-360 K

    NASA Technical Reports Server (NTRS)

    Lee, J. H.; Michael, J. V.; Payne, W. A.; Stief, L. J.

    1978-01-01

    Absolute rate constants for the reaction of atomic hydrogen with ozone were obtained over the temperature range 219-360 K by the flash photolysis-resonance fluorescence technique. The results can be expressed in Arrhenius form by K = (1.33 plus or minus 0.32)x10 to the minus 10 power exp (-449 plus or minus 58/T) cu cm/molecule/s (two standard deviations). The present work is compared to two previous determinations and is discussed theoretically.

  16. Absolute multilateration between spheres

    NASA Astrophysics Data System (ADS)

    Muelaner, Jody; Wadsworth, William; Azini, Maria; Mullineux, Glen; Hughes, Ben; Reichold, Armin

    2017-04-01

    Environmental effects typically limit the accuracy of large scale coordinate measurements in applications such as aircraft production and particle accelerator alignment. This paper presents an initial design for a novel measurement technique with analysis and simulation showing that that it could overcome the environmental limitations to provide a step change in large scale coordinate measurement accuracy. Referred to as absolute multilateration between spheres (AMS), it involves using absolute distance interferometry to directly measure the distances between pairs of plain steel spheres. A large portion of each sphere remains accessible as a reference datum, while the laser path can be shielded from environmental disturbances. As a single scale bar this can provide accurate scale information to be used for instrument verification or network measurement scaling. Since spheres can be simultaneously measured from multiple directions, it also allows highly accurate multilateration-based coordinate measurements to act as a large scale datum structure for localized measurements, or to be integrated within assembly tooling, coordinate measurement machines or robotic machinery. Analysis and simulation show that AMS can be self-aligned to achieve a theoretical combined standard uncertainty for the independent uncertainties of an individual 1 m scale bar of approximately 0.49 µm. It is also shown that combined with a 1 µm m‑1 standard uncertainty in the central reference system this could result in coordinate standard uncertainty magnitudes of 42 µm over a slender 1 m by 20 m network. This would be a sufficient step change in accuracy to enable next generation aerospace structures with natural laminar flow and part-to-part interchangeability.

  17. Large deviations and portfolio optimization

    NASA Astrophysics Data System (ADS)

    Sornette, Didier

    Risk control and optimal diversification constitute a major focus in the finance and insurance industries as well as, more or less consciously, in our everyday life. We present a discussion of the characterization of risks and of the optimization of portfolios that starts from a simple illustrative model and ends by a general functional integral formulation. A major item is that risk, usually thought of as one-dimensional in the conventional mean-variance approach, has to be addressed by the full distribution of losses. Furthermore, the time-horizon of the investment is shown to play a major role. We show the importance of accounting for large fluctuations and use the theory of Cramér for large deviations in this context. We first treat a simple model with a single risky asset that exemplifies the distinction between the average return and the typical return and the role of large deviations in multiplicative processes, and the different optimal strategies for the investors depending on their size. We then analyze the case of assets whose price variations are distributed according to exponential laws, a situation that is found to describe daily price variations reasonably well. Several portfolio optimization strategies are presented that aim at controlling large risks. We end by extending the standard mean-variance portfolio optimization theory, first within the quasi-Gaussian approximation and then using a general formulation for non-Gaussian correlated assets in terms of the formalism of functional integrals developed in the field theory of critical phenomena.

  18. Absolutely classical spin states

    NASA Astrophysics Data System (ADS)

    Bohnet-Waldraff, F.; Giraud, O.; Braun, D.

    2017-01-01

    We introduce the concept of "absolutely classical" spin states, in analogy to absolutely separable states of bipartite quantum systems. Absolutely classical states are states that remain classical (i.e., a convex sum of projectors on coherent states of a spin j ) under any unitary transformation applied to them. We investigate the maximal size of the ball of absolutely classical states centered on the maximally mixed state and derive a lower bound for its radius as a function of the total spin quantum number. We also obtain a numerical estimate of this maximal radius and compare it to the case of absolutely separable states.

  19. [Lateral mandibular deviations].

    PubMed

    Gotte, P

    1980-01-01

    The mandibular laterodeviation is one of the most evident malformations of the face, because it alters the lower third of the face. Etiologically it can be classified into: Static laterodeviations caused by teeth; Static laterodeviations caused by skeleton change: by monolateral hypertrophy (condyle, condyle and neck of the condyle, half mandible hypertrophy); by monolateral hypertrophy (congenital pathological); Dinamic laterodeviations functional. The midline displacement with posterior monolateral cross bite is caused by width discrepancy between the upper and lower dental arch resulting in a lateral shifting of the mandible. This laterodeviation is also called "laterale forced bite" or "articular cross bite". Articular cross bite is generally corrected by orthodontics during the interceptive period when the growth of the jaws is still present. In the author's opinion the orthognathic surgery is absolutely necessary for adult dental laterodeviation already stabilized. The skeletal laterodeviation must always be treated by orthognathic surgery. It is the author's practice to use the sagittal bilateral osteotomy at the angle and ramus level whose lines of osteotomy at the angle are different from one another depending on the displacement and rotation which one must do to the mandible to get contact surfaces which are larger enough to ensure proper union because the two mandibular halves have different lengths and different angles. This kind of operation normalizes the occlusion and is sometime sufficient to harmonize the oval of the lower third of the face. In the anterior part of the chin is still laterodeviated one continues with a wedge shaped osteotomy at the tip of the chin in order to reposition the tip to the midline and with an additional osteotomy at the hypertrophied angle level. If laterodeviation is joined by other bone malformations in can be considered a symptom which is more or less marked. In this case, therefore, laterodeviation is a part of a

  20. "Absolute" quantification in magnetic resonance spectroscopy: validation of a clinical protocol in multiple sclerosis.

    PubMed

    Bagory, Matthieu; Durand-Dubief, Françoise; Ibarrola, Danielle; Confavreux, Christian; Sappey-Marinier, Dominique

    2007-01-01

    MRS allows to measure cerebral metabolites, thus helping to characterize brain disease diagnosis and followup. Metabolite concentration quantification is usually based on metabolite ratio referring to creatine. If this metabolite concentration is supposed to be constant, it may vary in pathological processes. Therefore, "absolute" concentration methodology is needed. The aim of this study is to validate a clinical "absolute" quantification protocol through the development of an external metabolic phantom, calibration and correction, and the investigation of reproducibility issues. When phantom stability was investigated by a short-term and a long-term reproducibility study, both Standard Deviations (SD) were in agreement with literature values. This "absolute" quantification method was applied to patients with Multiple Sclerosis (MS). The results show a significant decrease in both N-Acetyl Aspartate (NAA) and choline concentrations.

  1. Diagnosis of human herpes virus 1 and 2 (HHV-1 and HHV-2): use of a synthetic standard curve for absolute quantification by real time polymerase chain reaction

    PubMed Central

    Lima, Lyana Rodrigues Pinto; da Silva, Amanda Perse; Schmidt-Chanasit, Jonas; de Paula, Vanessa Salete

    2017-01-01

    The use of quantitative real time polymerase chain reaction (qPCR) for herpesvirus detection has improved the sensitivity and specificity of diagnosis, as it is able to detect shedding episodes in the absence of clinical lesions and diagnose clinical specimens that have low viral loads. With an aim to improve the detection and quantification of herpesvirus by qPCR, synthetic standard curves for human herpesvirus 1 and 2 (HHV-1 and HHV-2) targeting regions gD and gG, respectively, were designed and evaluated. The results show that synthetic curves can replace DNA standard curves in diagnostic herpes qPCR. PMID:28225902

  2. Diagnosis of human herpes virus 1 and 2 (HHV-1 and HHV-2): use of a synthetic standard curve for absolute quantification by real time polymerase chain reaction.

    PubMed

    Lima, Lyana Rodrigues Pinto; Silva, Amanda Perse da; Schmidt-Chanasit, Jonas; Paula, Vanessa Salete de

    2017-02-16

    The use of quantitative real time polymerase chain reaction (qPCR) for herpesvirus detection has improved the sensitivity and specificity of diagnosis, as it is able to detect shedding episodes in the absence of clinical lesions and diagnose clinical specimens that have low viral loads. With an aim to improve the detection and quantification of herpesvirus by qPCR, synthetic standard curves for human herpesvirus 1 and 2 (HHV-1 and HHV-2) targeting regions gD and gG, respectively, were designed and evaluated. The results show that synthetic curves can replace DNA standard curves in diagnostic herpes qPCR.

  3. Diagnosis of human herpes virus 1 and 2 (HHV-1 and HHV-2): use of a synthetic standard curve for absolute quantification by real time polymerase chain reaction.

    PubMed

    Lima, Lyana Rodrigues Pinto; Silva, Amanda Perse da; Schmidt-Chanasit, Jonas; Paula, Vanessa Salete de

    2017-03-01

    The use of quantitative real time polymerase chain reaction (qPCR) for herpesvirus detection has improved the sensitivity and specificity of diagnosis, as it is able to detect shedding episodes in the absence of clinical lesions and diagnose clinical specimens that have low viral loads. With an aim to improve the detection and quantification of herpesvirus by qPCR, synthetic standard curves for human herpesvirus 1 and 2 (HHV-1 and HHV-2) targeting regions gD and gG, respectively, were designed and evaluated. The results show that synthetic curves can replace DNA standard curves in diagnostic herpes qPCR.

  4. Absolute nuclear material assay

    DOEpatents

    Prasad, Manoj K [Pleasanton, CA; Snyderman, Neal J [Berkeley, CA; Rowland, Mark S [Alamo, CA

    2012-05-15

    A method of absolute nuclear material assay of an unknown source comprising counting neutrons from the unknown source and providing an absolute nuclear material assay utilizing a model to optimally compare to the measured count distributions. In one embodiment, the step of providing an absolute nuclear material assay comprises utilizing a random sampling of analytically computed fission chain distributions to generate a continuous time-evolving sequence of event-counts by spreading the fission chain distribution in time.

  5. Absolute nuclear material assay

    DOEpatents

    Prasad, Manoj K.; Snyderman, Neal J.; Rowland, Mark S.

    2010-07-13

    A method of absolute nuclear material assay of an unknown source comprising counting neutrons from the unknown source and providing an absolute nuclear material assay utilizing a model to optimally compare to the measured count distributions. In one embodiment, the step of providing an absolute nuclear material assay comprises utilizing a random sampling of analytically computed fission chain distributions to generate a continuous time-evolving sequence of event-counts by spreading the fission chain distribution in time.

  6. Absolute Quantification of Prion Protein (90-231) Using Stable Isotope-Labeled Chymotryptic Peptide Standards in a LC-MRM AQUA Workflow

    NASA Astrophysics Data System (ADS)

    Sturm, Robert; Sheynkman, Gloria; Booth, Clarissa; Smith, Lloyd M.; Pedersen, Joel A.; Li, Lingjun

    2012-09-01

    Substantial evidence indicates that the disease-associated conformer of the prion protein (PrPTSE) constitutes the etiologic agent in prion diseases. These diseases affect multiple mammalian species. PrPTSE has the ability to convert the conformation of the normal prion protein (PrPC) into a β-sheet rich form resistant to proteinase K digestion. Common immunological techniques lack the sensitivity to detect PrPTSE at subfemtomole levels, whereas animal bioassays, cell culture, and in vitro conversion assays offer higher sensitivity but lack the high-throughput the immunological assays offer. Mass spectrometry is an attractive alternative to the above assays as it offers high-throughput, direct measurement of a protein's signature peptide, often with subfemtomole sensitivities. Although a liquid chromatography-multiple reaction monitoring (LC-MRM) method has been reported for PrPTSE, the chemical composition and lack of amino acid sequence conservation of the signature peptide may compromise its accuracy and make it difficult to apply to multiple species. Here, we demonstrate that an alternative protease (chymotrypsin) can produce signature peptides suitable for a LC-MRM absolute quantification (AQUA) experiment. The new method offers several advantages, including: (1) a chymotryptic signature peptide lacking chemically active residues (Cys, Met) that can confound assay accuracy; (2) low attomole limits of detection and quantitation (LOD and LOQ); and (3) a signature peptide retaining the same amino acid sequence across most mammals naturally susceptible to prion infection as well as important laboratory models. To the authors' knowledge, this is the first report on the use of a non-tryptic peptide in a LC-MRM AQUA workflow.

  7. Searching for the Norm in a System of Absolutes: A Case Study of Standards-Based Accountability Reform in Pre-Kindergarten

    ERIC Educational Resources Information Center

    Brown, Christopher

    2011-01-01

    Research Findings: The emergence of standards-based accountability reforms in early childhood education has created new challenges for the field. This article presents findings from a case study that explored how stakeholders in a large urban pre-kindergarten program struggled to implement an assessment tool that aligned the normative academic…

  8. How do we assign punishment? The impact of minimal and maximal standards on the evaluation of deviants.

    PubMed

    Kessler, Thomas; Neumann, Jörg; Mummendey, Amélie; Berthold, Anne; Schubert, Thomas; Waldzus, Sven

    2010-09-01

    To explain the determinants of negative behavior toward deviants (e.g., punishment), this article examines how people evaluate others on the basis of two types of standards: minimal and maximal. Minimal standards focus on an absolute cutoff point for appropriate behavior; accordingly, the evaluation of others varies dichotomously between acceptable or unacceptable. Maximal standards focus on the degree of deviation from that standard; accordingly, the evaluation of others varies gradually from positive to less positive. This framework leads to the prediction that violation of minimal standards should elicit punishment regardless of the degree of deviation, whereas punishment in response to violations of maximal standards should depend on the degree of deviation. Four studies assessed or manipulated the type of standard and degree of deviation displayed by a target. Results consistently showed the expected interaction between type of standard (minimal and maximal) and degree of deviation on punishment behavior.

  9. Explorations in Statistics: Standard Deviations and Standard Errors

    ERIC Educational Resources Information Center

    Curran-Everett, Douglas

    2008-01-01

    Learning about statistics is a lot like learning about science: the learning is more meaningful if you can actively explore. This series in "Advances in Physiology Education" provides an opportunity to do just that: we will investigate basic concepts in statistics using the free software package R. Because this series uses R solely as a vehicle…

  10. Real-time RT-PCR for detection, identification and absolute quantification of viral haemorrhagic septicaemia virus using different types of standards.

    PubMed

    Lopez-Vazquez, C; Bandín, I; Dopazo, C P

    2015-05-21

    In the present study, 2 systems of real-time RT-PCR-one based on SYBR Green and the other on TaqMan-were designed to detect strains from any genotype of viral haemorrhagic septicaemia virus (VHSV), with high sensitivity and repeatability/reproducibility. In addition, the method was optimized for quantitative purposes (qRT-PCR), and standard curves with different types of reference templates were constructed and compared. Specificity was tested against 26 isolates from 4 genotypes. The sensitivity of the procedures was first tested against cell culture isolation, obtaining a limit of detection (LD) of 100 TCID50 ml-1 (100-fold below the LD using cell culture), at a threshold cycle value (Ct) of 36. Sensitivity was also evaluated using RNA from crude (LD = 1 fg; 160 genome copies) and purified virus (100 ag; 16 copies), plasmid DNA (2 copies) and RNA transcript (15 copies). No differences between both chemistries were observed in sensitivity and dynamic range. To evaluate repeatability and reproducibility, all experiments were performed in triplicate and on 3 different days, by workers with different levels of experience, obtaining Ct values with coefficients of variation always <5. This fact, together with the high efficiency and R2 values of the standard curves, encouraged us to analyse the reliability of the method for viral quantification. The results not only demonstrated that the procedure can be used for detection, identification and quantification of this virus, but also demonstrated a clear correlation between the regression lines obtained with different standards, which will help scientists to compare sensitivity results between different studies.

  11. Absolute quantitation of protein posttranslational modification isoform.

    PubMed

    Yang, Zhu; Li, Ning

    2015-01-01

    Mass spectrometry has been widely applied in characterization and quantification of proteins from complex biological samples. Because the numbers of absolute amounts of proteins are needed in construction of mathematical models for molecular systems of various biological phenotypes and phenomena, a number of quantitative proteomic methods have been adopted to measure absolute quantities of proteins using mass spectrometry. The liquid chromatography-tandem mass spectrometry (LC-MS/MS) coupled with internal peptide standards, i.e., the stable isotope-coded peptide dilution series, which was originated from the field of analytical chemistry, becomes a widely applied method in absolute quantitative proteomics research. This approach provides more and more absolute protein quantitation results of high confidence. As quantitative study of posttranslational modification (PTM) that modulates the biological activity of proteins is crucial for biological science and each isoform may contribute a unique biological function, degradation, and/or subcellular location, the absolute quantitation of protein PTM isoforms has become more relevant to its biological significance. In order to obtain the absolute cellular amount of a PTM isoform of a protein accurately, impacts of protein fractionation, protein enrichment, and proteolytic digestion yield should be taken into consideration and those effects before differentially stable isotope-coded PTM peptide standards are spiked into sample peptides have to be corrected. Assisted with stable isotope-labeled peptide standards, the absolute quantitation of isoforms of posttranslationally modified protein (AQUIP) method takes all these factors into account and determines the absolute amount of a protein PTM isoform from the absolute amount of the protein of interest and the PTM occupancy at the site of the protein. The absolute amount of the protein of interest is inferred by quantifying both the absolute amounts of a few PTM

  12. Absolute calibration of optical flats

    DOEpatents

    Sommargren, Gary E.

    2005-04-05

    The invention uses the phase shifting diffraction interferometer (PSDI) to provide a true point-by-point measurement of absolute flatness over the surface of optical flats. Beams exiting the fiber optics in a PSDI have perfect spherical wavefronts. The measurement beam is reflected from the optical flat and passed through an auxiliary optic to then be combined with the reference beam on a CCD. The combined beams include phase errors due to both the optic under test and the auxiliary optic. Standard phase extraction algorithms are used to calculate this combined phase error. The optical flat is then removed from the system and the measurement fiber is moved to recombine the two beams. The newly combined beams include only the phase errors due to the auxiliary optic. When the second phase measurement is subtracted from the first phase measurement, the absolute phase error of the optical flat is obtained.

  13. 40 CFR 63.1965 - What is a deviation?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Emission Standards for Hazardous Air Pollutants: Municipal Solid Waste Landfills General and Continuing... of the landfill monitoring and SSM plan requirements, deviations include the items in paragraphs (a.... (c) A deviation occurs when a SSM plan is not developed or maintained on site....

  14. 40 CFR 63.1965 - What is a deviation?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Emission Standards for Hazardous Air Pollutants: Municipal Solid Waste Landfills General and Continuing... of the landfill monitoring and SSM plan requirements, deviations include the items in paragraphs (a.... (c) A deviation occurs when a SSM plan is not developed or maintained on site....

  15. 40 CFR 63.1965 - What is a deviation?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Emission Standards for Hazardous Air Pollutants: Municipal Solid Waste Landfills General and Continuing... of the landfill monitoring and SSM plan requirements, deviations include the items in paragraphs (a.... (c) A deviation occurs when a SSM plan is not developed or maintained on site....

  16. Absolute and relative blindsight.

    PubMed

    Balsdon, Tarryn; Azzopardi, Paul

    2015-03-01

    The concept of relative blindsight, referring to a difference in conscious awareness between conditions otherwise matched for performance, was introduced by Lau and Passingham (2006) as a way of identifying the neural correlates of consciousness (NCC) in fMRI experiments. By analogy, absolute blindsight refers to a difference between performance and awareness regardless of whether it is possible to match performance across conditions. Here, we address the question of whether relative and absolute blindsight in normal observers can be accounted for by response bias. In our replication of Lau and Passingham's experiment, the relative blindsight effect was abolished when performance was assessed by means of a bias-free 2AFC task or when the criterion for awareness was varied. Furthermore, there was no evidence of either relative or absolute blindsight when both performance and awareness were assessed with bias-free measures derived from confidence ratings using signal detection theory. This suggests that both relative and absolute blindsight in normal observers amount to no more than variations in response bias in the assessment of performance and awareness. Consideration of the properties of psychometric functions reveals a number of ways in which relative and absolute blindsight could arise trivially and elucidates a basis for the distinction between Type 1 and Type 2 blindsight.

  17. Interventions for dissociated vertical deviation

    PubMed Central

    Hatt, Sarah R; Wang, Xue; Holmes, Jonathan M

    2015-01-01

    Background The term “strabismus” describes misalignment of the eyes. One or both eyes may deviate inward, outward, upward, or downward. Dissociated vertical deviation (DVD) is a well-recognized type of upward drifting of one or both eyes, which can occur in children or adults. DVD often develops in the context of infantile- or childhood-onset horizontal strabismus, either esotropia (inward-turning) or exotropia (outward-turning). For some individuals, DVD remains controlled and can only be detected during clinical testing. For others, DVD becomes spontaneously “manifest” and the eye drifts up of its own accord. Spontaneously manifest DVD can be difficult to control and often causes psychosocial concerns. Traditionally, DVD has been thought to be asymptomatic, although some individuals have double vision. More recently it has been suggested that individuals with DVD may also suffer from eyestrain. Treatment for DVD may be sought either due to psychosocial concerns or because of these symptoms. The standard treatment for DVD is a surgical procedure; non-surgical treatments are offered less commonly. Although there are many studies evaluating different management options for the correction of DVD, a lack of clarity remains regarding which treatments are most effective. Objectives The objective of this review was to determine the effectiveness and safety of various surgical and non-surgical interventions in randomized controlled trials of participants with DVD. Search methods We searched CENTRAL (which contains the Cochrane Eyes and Vision Trials Register) (2015, Issue 8), Ovid MEDLINE, Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE Daily, Ovid OLDMEDLINE (January 1946 to August 2015), EMBASE (January 1980 to August 2015), PubMed (1948 to August 2015), Latin American and Caribbean Health Sciences Literature Database (LILACS) (1982 to August 2015), the metaRegister of Controlled Trials (mRCT) (www.controlled-trials.com) (last searched 3

  18. The absolute path command

    SciTech Connect

    Moody, A.

    2012-05-11

    The ap command traveres all symlinks in a given file, directory, or executable name to identify the final absolute path. It can print just the final path, each intermediate link along with the symlink chan, and the permissions and ownership of each directory component in the final path. It has functionality similar to "which", except that it shows the final path instead of the first path. It is also similar to "pwd", but it can provide the absolute path to a relative directory from the current working directory.

  19. Large deviations in Taylor dispersion

    NASA Astrophysics Data System (ADS)

    Kahlen, Marcel; Engel, Andreas; Van den Broeck, Christian

    2017-01-01

    We establish a link between the phenomenon of Taylor dispersion and the theory of empirical distributions. Using this connection, we derive, upon applying the theory of large deviations, an alternative and much more precise description of the long-time regime for Taylor dispersion.

  20. Simple and accurate empirical absolute volume calibration of a multi-sensor fringe projection system

    NASA Astrophysics Data System (ADS)

    Gdeisat, Munther; Qudeisat, Mohammad; AlSa`d, Mohammed; Burton, David; Lilley, Francis; Ammous, Marwan M. M.

    2016-05-01

    This paper suggests a novel absolute empirical calibration method for a multi-sensor fringe projection system. The optical setup of the projector-camera sensor can be arbitrary. The term absolute calibration here means that the centre of the three dimensional coordinates in the resultant calibrated volume coincides with a preset centre to the three-dimensional real-world coordinate system. The use of a zero-phase fringe marking spot is proposed to increase depth calibration accuracy, where the spot centre is determined with sub-pixel accuracy. Also, a new method is proposed for transversal calibration. Depth and transversal calibration methods have been tested using both single sensor and three-sensor fringe projection systems. The standard deviation of the error produced by this system is 0.25 mm. The calibrated volume produced by this method is 400 mm×400 mm×140 mm.

  1. Management of paretic vertical deviations.

    PubMed

    Archer, Steven M

    2011-01-01

    Paretic vertical deviations are characterized by complex patterns of incomitance that make them some of the most challenging strabismus problems to treat. Optimum results are obtained by performing surgery on those muscles, selected from among the eight cyclovertical muscles in the two eyes, that minimize the incomitance. In superior oblique paresis the additional factors of torticollis and torsion need to be addressed and aberrant regeneration can alter the surgical plan in third nerve paresis.

  2. Large Deviations for Random Trees

    PubMed Central

    Heitsch, Christine

    2010-01-01

    We consider large random trees under Gibbs distributions and prove a Large Deviation Principle (LDP) for the distribution of degrees of vertices of the tree. The LDP rate function is given explicitly. An immediate consequence is a Law of Large Numbers for the distribution of vertex degrees in a large random tree. Our motivation for this study comes from the analysis of RNA secondary structures. PMID:20216937

  3. Note onset deviations as musical piece signatures.

    PubMed

    Serrà, Joan; Özaslan, Tan Hakan; Arcos, Josep Lluis

    2013-01-01

    A competent interpretation of a musical composition presents several non-explicit departures from the written score. Timing variations are perhaps the most important ones: they are fundamental for expressive performance and a key ingredient for conferring a human-like quality to machine-based music renditions. However, the nature of such variations is still an open research question, with diverse theories that indicate a multi-dimensional phenomenon. In the present study, we consider event-shift timing variations and show that sequences of note onset deviations are robust and reliable predictors of the musical piece being played, irrespective of the performer. In fact, our results suggest that only a few consecutive onset deviations are already enough to identify a musical composition with statistically significant accuracy. We consider a mid-size collection of commercial recordings of classical guitar pieces and follow a quantitative approach based on the combination of standard statistical tools and machine learning techniques with the semi-automatic estimation of onset deviations. Besides the reported results, we believe that the considered materials and the methodology followed widen the testing ground for studying musical timing and could open new perspectives in related research fields.

  4. Note Onset Deviations as Musical Piece Signatures

    PubMed Central

    Serrà, Joan; Özaslan, Tan Hakan; Arcos, Josep Lluis

    2013-01-01

    A competent interpretation of a musical composition presents several non-explicit departures from the written score. Timing variations are perhaps the most important ones: they are fundamental for expressive performance and a key ingredient for conferring a human-like quality to machine-based music renditions. However, the nature of such variations is still an open research question, with diverse theories that indicate a multi-dimensional phenomenon. In the present study, we consider event-shift timing variations and show that sequences of note onset deviations are robust and reliable predictors of the musical piece being played, irrespective of the performer. In fact, our results suggest that only a few consecutive onset deviations are already enough to identify a musical composition with statistically significant accuracy. We consider a mid-size collection of commercial recordings of classical guitar pieces and follow a quantitative approach based on the combination of standard statistical tools and machine learning techniques with the semi-automatic estimation of onset deviations. Besides the reported results, we believe that the considered materials and the methodology followed widen the testing ground for studying musical timing and could open new perspectives in related research fields. PMID:23935971

  5. Improved Strategies and Optimization of Calibration Models for Real-time PCR Absolute Quantification

    EPA Science Inventory

    Real-time PCR absolute quantification applications rely on the use of standard curves to make estimates of DNA target concentrations in unknown samples. Traditional absolute quantification approaches dictate that a standard curve must accompany each experimental run. However, t...

  6. The new Absolute Quantum Gravimeter (AQG): first results and perspectives

    NASA Astrophysics Data System (ADS)

    Bonvalot, Sylvain; Le Moigne, Nicolas; Merlet, Sebastien; Desruelle, Bruno; Lautier-Gaud, Jean; Menoret, Vincent; Vermeulen, Pierre

    2016-04-01

    the AQG01. This paper summarizes the latest results obtained from these experiments. The evaluation of the AQG01 is still in progress but this study confirmed that the AQG01 enables absolute gravity measurements with a sensitivity of 2 μGal standard deviation after 1000 s of data integration. Perspectives of expected instrumental developments for monitoring both spatial and temporal gravity variations at the microGal level in both laboratory and field conditions will be also discussed.

  7. Absolute calibration of an ultraviolet spectrometer using a stabilized laser and a cryogenic cavity radiometer

    NASA Technical Reports Server (NTRS)

    Jauniskis, L.; Foukal, P.; Kochling, H.

    1992-01-01

    We carry out the calibration of an ultraviolet spectrometer by using a cryogenic electrical-substitution radiometer and intensity-stabilized laser sources. A comparison of the error budgets for the laser-based calibration described here and for a calibration using a type-FEL tungsten spectral-irradiance standard indicates that this technique could provide an improvement of a factor of about three in the uncertainty of the spectrometer calibration, resulting in an absolute accuracy (standard deviation of three) of about 1 percent at 257 nm. The technique described here might significantly improve the accuracy of calibrations on NASA ozone-monitoring and solar ultraviolet-monitoring spectrophotometers when used to complement present procedures that employ lamps and the SURF II synchrotron ultraviolet radiation facility at the National Institute of Standards and Technology.

  8. Absolute calibration of an ultraviolet spectrometer using a stabilized laser and a cryogenic cavity radiometer.

    PubMed

    Jauniskis, L; Foukal, P; Kochling, H

    1992-09-20

    We carry out the calibration of an ultraviolet spectrometer by using a cryogenic electrical-substitution radiometer and intensity-stabilized laser sources. A comparison of the error budgets for the laser-based calibration described here and for a calibration using a type-FEL tungsten spectral-irradiance standard indicates that this technique could provide an improvement of a factor of ~3 in the uncertainty of the spectrometer calibration, resulting in an absolute accuracy (standard deviation of 3) of ~1% at 257 nm. The technique described here might significantly improve the accuracy of calibrations on NASA ozone-monitoring and solar ultraviolet-monitoring spectrophotometers when used to complement present procedures that employ lamps and the SURF II synchrotron ultraviolet radiation facility at the National Institute of Standards and Technology.

  9. Absolute airborne gravimetry

    NASA Astrophysics Data System (ADS)

    Baumann, Henri

    This work consists of a feasibility study of a first stage prototype airborne absolute gravimeter system. In contrast to relative systems, which are using spring gravimeters, the measurements acquired by absolute systems are uncorrelated and the instrument is not suffering from problems like instrumental drift, frequency response of the spring and possible variation of the calibration factor. The major problem we had to resolve were to reduce the influence of the non-gravitational accelerations included in the measurements. We studied two different approaches to resolve it: direct mechanical filtering, and post-processing digital compensation. The first part of the work describes in detail the different mechanical passive filters of vibrations, which were studied and tested in the laboratory and later in a small truck in movement. For these tests as well as for the airborne measurements an absolute gravimeter FG5-L from Micro-G Ltd was used together with an Inertial navigation system Litton-200, a vertical accelerometer EpiSensor, and GPS receivers for positioning. These tests showed that only the use of an optical table gives acceptable results. However, it is unable to compensate for the effects of the accelerations of the drag free chamber. The second part describes the strategy of the data processing. It is based on modeling the perturbing accelerations by means of GPS, EpiSensor and INS data. In the third part the airborne experiment is described in detail, from the mounting in the aircraft and data processing to the different problems encountered during the evaluation of the quality and accuracy of the results. In the part of data processing the different steps conducted from the raw apparent gravity data and the trajectories to the estimation of the true gravity are explained. A comparison between the estimated airborne data and those obtained by ground upward continuation at flight altitude allows to state that airborne absolute gravimetry is feasible and

  10. Cosmology with negative absolute temperatures

    NASA Astrophysics Data System (ADS)

    Vieira, J. P. P.; Byrnes, Christian T.; Lewis, Antony

    2016-08-01

    Negative absolute temperatures (NAT) are an exotic thermodynamical consequence of quantum physics which has been known since the 1950's (having been achieved in the lab on a number of occasions). Recently, the work of Braun et al. [1] has rekindled interest in negative temperatures and hinted at a possibility of using NAT systems in the lab as dark energy analogues. This paper goes one step further, looking into the cosmological consequences of the existence of a NAT component in the Universe. NAT-dominated expanding Universes experience a borderline phantom expansion (w < -1) with no Big Rip, and their contracting counterparts are forced to bounce after the energy density becomes sufficiently large. Both scenarios might be used to solve horizon and flatness problems analogously to standard inflation and bouncing cosmologies. We discuss the difficulties in obtaining and ending a NAT-dominated epoch, and possible ways of obtaining density perturbations with an acceptable spectrum.

  11. 48 CFR 3401.404 - Class deviations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 7 2012-10-01 2012-10-01 false Class deviations. 3401.404 Section 3401.404 Federal Acquisition Regulations System DEPARTMENT OF EDUCATION ACQUISITION REGULATION GENERAL ED ACQUISITION REGULATION SYSTEM Deviations 3401.404 Class deviations. A class deviation from...

  12. 48 CFR 3401.404 - Class deviations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 7 2013-10-01 2012-10-01 true Class deviations. 3401.404 Section 3401.404 Federal Acquisition Regulations System DEPARTMENT OF EDUCATION ACQUISITION REGULATION GENERAL ED ACQUISITION REGULATION SYSTEM Deviations 3401.404 Class deviations. A class deviation from...

  13. 48 CFR 3401.404 - Class deviations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Class deviations. 3401.404 Section 3401.404 Federal Acquisition Regulations System DEPARTMENT OF EDUCATION ACQUISITION REGULATION GENERAL ED ACQUISITION REGULATION SYSTEM Deviations 3401.404 Class deviations. A class deviation from...

  14. 48 CFR 3401.404 - Class deviations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Class deviations. 3401.404 Section 3401.404 Federal Acquisition Regulations System DEPARTMENT OF EDUCATION ACQUISITION REGULATION GENERAL ED ACQUISITION REGULATION SYSTEM Deviations 3401.404 Class deviations. A class deviation from...

  15. 48 CFR 3401.404 - Class deviations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 7 2014-10-01 2014-10-01 false Class deviations. 3401.404 Section 3401.404 Federal Acquisition Regulations System DEPARTMENT OF EDUCATION ACQUISITION REGULATION GENERAL ED ACQUISITION REGULATION SYSTEM Deviations 3401.404 Class deviations. A class deviation from...

  16. Results of the first North American comparison of absolute gravimeters, NACAG-2010

    NASA Astrophysics Data System (ADS)

    Schmerge, D.; Francis, O.; Henton, J.; Ingles, D.; Jones, D.; Kennedy, J.; Krauterbluth, K.; Liard, J.; Newell, D.; Sands, R.; Schiel, A.; Silliker, J.; van Westrum, D.

    2012-08-01

    The first North American Comparison of absolute gravimeters (NACAG-2010) was hosted by the National Oceanic and Atmospheric Administration at its newly renovated Table Mountain Geophysical Observatory (TMGO) north of Boulder, Colorado, in October 2010. NACAG-2010 and the renovation of TMGO are part of NGS's GRAV-D project (Gravity for the Redefinition of the American Vertical Datum). Nine absolute gravimeters from three countries participated in the comparison. Before the comparison, the gravimeter operators agreed to a protocol describing the strategy to measure, calculate, and present the results. Nine sites were used to measure the free-fall acceleration of g. Each gravimeter measured the value of g at a subset of three of the sites, for a total set of 27 g-values for the comparison. The absolute gravimeters agree with one another with a standard deviation of 1.6 μGal (1 Gal ≡ 1 cm s -2). The minimum and maximum offsets are -2.8 and 2.7 μGal. This is an excellent agreement and can be attributed to multiple factors, including gravimeters that were in good working order, good operators, a quiet observatory, and a short duration time for the experiment. These results can be used to standardize gravity surveys internationally.

  17. Results of the first North American comparison of absolute gravimeters, NACAG-2010

    USGS Publications Warehouse

    Schmerge, David; Francis, Olvier; Henton, J.; Ingles, D.; Jones, D.; Kennedy, Jeffrey R.; Krauterbluth, K.; Liard, J.; Newell, D.; Sands, R.; Schiel, J.; Silliker, J.; van Westrum, D.

    2012-01-01

    The first North American Comparison of absolute gravimeters (NACAG-2010) was hosted by the National Oceanic and Atmospheric Administration at its newly renovated Table Mountain Geophysical Observatory (TMGO) north of Boulder, Colorado, in October 2010. NACAG-2010 and the renovation of TMGO are part of NGS’s GRAV-D project (Gravity for the Redefinition of the American Vertical Datum). Nine absolute gravimeters from three countries participated in the comparison. Before the comparison, the gravimeter operators agreed to a protocol describing the strategy to measure, calculate, and present the results. Nine sites were used to measure the free-fall acceleration of g. Each gravimeter measured the value of g at a subset of three of the sites, for a total set of 27 g-values for the comparison. The absolute gravimeters agree with one another with a standard deviation of 1.6 µGal (1 Gal = 1 cm s-2). The minimum and maximum offsets are -2.8 and 2.7 µGal. This is an excellent agreement and can be attributed to multiple factors, including gravimeters that were in good working order, good operators, a quiet observatory, and a short duration time for the experiment. These results can be used to standardize gravity surveys internationally.

  18. Absolute-structure reports.

    PubMed

    Flack, Howard D

    2013-08-01

    All the 139 noncentrosymmetric crystal structures published in Acta Crystallographica Section C between January 2011 and November 2012 inclusive have been used as the basis of a detailed study of the reporting of absolute structure. These structure determinations cover a wide range of space groups, chemical composition and resonant-scattering contribution. Defining A and D as the average and difference of the intensities of Friedel opposites, their level of fit has been examined using 2AD and selected-D plots. It was found, regardless of the expected resonant-scattering contribution to Friedel opposites, that the Friedel-difference intensities are often dominated by random uncertainty and systematic error. An analysis of data collection strategy is provided. It is found that crystal-structure determinations resulting in a Flack parameter close to 0.5 may not necessarily be from crystals twinned by inversion. Friedifstat is shown to be a robust estimator of the resonant-scattering contribution to Friedel opposites, very little affected by the particular space group of a structure nor by the occupation of special positions. There is considerable confusion in the text of papers presenting achiral noncentrosymmetric crystal structures. Recommendations are provided for the optimal way of treating noncentrosymmetric crystal structures for which the experimenter has no interest in determining the absolute structure.

  19. Absolute Distance Measurement with the MSTAR Sensor

    NASA Technical Reports Server (NTRS)

    Lay, Oliver P.; Dubovitsky, Serge; Peters, Robert; Burger, Johan; Ahn, Seh-Won; Steier, William H.; Fetterman, Harrold R.; Chang, Yian

    2003-01-01

    The MSTAR sensor (Modulation Sideband Technology for Absolute Ranging) is a new system for measuring absolute distance, capable of resolving the integer cycle ambiguity of standard interferometers, and making it possible to measure distance with sub-nanometer accuracy. The sensor uses a single laser in conjunction with fast phase modulators and low frequency detectors. We describe the design of the system - the principle of operation, the metrology source, beamlaunching optics, and signal processing - and show results for target distances up to 1 meter. We then demonstrate how the system can be scaled to kilometer-scale distances.

  20. Evaluating least absolute deviation regression as an inverse model in groundwater flow calibration

    NASA Astrophysics Data System (ADS)

    Huddleston, John Matthew

    Though information regarding children's mental health is increasing, and we know that approximately 20% of children meet criteria for a mental disorder, little is known about the characteristics of the child client population at community mental health clinics. This study is an exploratory analysis of the demographic and treatment characteristics of the child client population at a psychology training clinic/community mental health center. Demographic and treatment information is presented and compared across various service categories as well as diagnostic categories. Comparisons between those served during the first six years and those served during the second six years of the study period are also made. Results are discussed in terms of generalizability of results as well as available information from the literature.

  1. Absolute Equilibrium Entropy

    NASA Technical Reports Server (NTRS)

    Shebalin, John V.

    1997-01-01

    The entropy associated with absolute equilibrium ensemble theories of ideal, homogeneous, fluid and magneto-fluid turbulence is discussed and the three-dimensional fluid case is examined in detail. A sigma-function is defined, whose minimum value with respect to global parameters is the entropy. A comparison is made between the use of global functions sigma and phase functions H (associated with the development of various H-theorems of ideal turbulence). It is shown that the two approaches are complimentary though conceptually different: H-theorems show that an isolated system tends to equilibrium while sigma-functions allow the demonstration that entropy never decreases when two previously isolated systems are combined. This provides a more complete picture of entropy in the statistical mechanics of ideal fluids.

  2. Age-specific absolute and relative organ weight distributions for B6C3F1 mice.

    PubMed

    Marino, Dale J

    2012-01-01

    The B6C3F1 mouse is the standard mouse strain used in toxicology studies conducted by the National Cancer Institute (NCI) and the National Toxicology Program (NTP). While numerous reports have been published on growth, survival, and tumor incidence, no overall compilation of organ weight data is available. Importantly, organ weight change is an endpoint used by regulatory agencies to develop toxicity reference values (TRVs) for use in human health risk assessments. Furthermore, physiologically based pharmacokinetic (PBPK) models, which utilize relative organ weights, are increasingly being used to develop TRVs. Therefore, all available absolute and relative organ weight data for untreated control B6C3F1 mice were collected from NCI/NTP studies in order to develop age-specific distributions. Results show that organ weights were collected more frequently in NCI/NTP studies at 2-wk (60 studies), 3-mo (147 studies), and 15-mo (40 studies) intervals than at other intervals, and more frequently from feeding and inhalation than drinking water studies. Liver, right kidney, lung, heart, thymus, and brain weights were most frequently collected. From the collected data, the mean and standard deviation for absolute and relative organ weights were calculated. Results show age-related increases in absolute liver, right kidney, lung, and heart weights and relatively stable brain and right testis weights. The results suggest a general variability trend in absolute organ weights of brain < right testis < right kidney < heart < liver < lung < spleen < thymus. This report describes the results of this effort.

  3. Combining sub-Nyquist sampling and chirp decomposition for a high-precision and speed absolute distance measurement method.

    PubMed

    Liu, Guodong; Lu, Cheng; Liu, Bingguo; Chen, Fengdong; Gan, Yu

    2016-12-10

    A high-precision and speed absolute distance measurement based on swept-wavelength interferometry is reported. A powerful method combining sub-Nyquist sampling and chirp decomposition for dispersion mismatch compensation is proposed. A standard deviation of 0.72 μm is obtained for the measurement of a target located at 3.9 m, which is better than the traditional method. The measurement can be completed in 1.9 s when the frequency range is 4.26 THz, which is much better than chirp decomposition without sub-Nyquist sampling.

  4. 14 CFR 1260.7 - Deviations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Deviations. 1260.7 Section 1260.7 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION GRANTS AND COOPERATIVE AGREEMENTS General § 1260.7 Deviations. (a) A deviation is required for any of the following: (1) When a...

  5. 14 CFR 1260.7 - Deviations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Deviations. 1260.7 Section 1260.7 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION GRANTS AND COOPERATIVE AGREEMENTS General § 1260.7 Deviations. (a) A deviation is required for any of the following: (1) When a...

  6. 14 CFR 1260.7 - Deviations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Deviations. 1260.7 Section 1260.7 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION GRANTS AND COOPERATIVE AGREEMENTS General § 1260.7 Deviations. (a) A deviation is required for any of the following: (1) When a...

  7. 14 CFR § 1260.7 - Deviations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false Deviations. § 1260.7 Section § 1260.7 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION GRANTS AND COOPERATIVE AGREEMENTS General § 1260.7 Deviations. (a) A deviation is required for any of the following: (1) When a...

  8. 14 CFR 1260.7 - Deviations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Deviations. 1260.7 Section 1260.7 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION GRANTS AND COOPERATIVE AGREEMENTS General § 1260.7 Deviations. (a) A deviation is required for any of the following: (1) When a...

  9. 10 CFR 602.4 - Deviations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Deviations. 602.4 Section 602.4 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS EPIDEMIOLOGY AND OTHER HEALTH STUDIES FINANCIAL ASSISTANCE PROGRAM § 602.4 Deviations. (a) Single-case deviations from this part may be authorized in writing by...

  10. 48 CFR 3401.403 - Individual deviations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 7 2013-10-01 2012-10-01 true Individual deviations. 3401.403 Section 3401.403 Federal Acquisition Regulations System DEPARTMENT OF EDUCATION ACQUISITION REGULATION GENERAL ED ACQUISITION REGULATION SYSTEM Deviations 3401.403 Individual deviations. An...

  11. 48 CFR 3401.403 - Individual deviations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Individual deviations. 3401.403 Section 3401.403 Federal Acquisition Regulations System DEPARTMENT OF EDUCATION ACQUISITION REGULATION GENERAL ED ACQUISITION REGULATION SYSTEM Deviations 3401.403 Individual deviations. An...

  12. 48 CFR 3401.403 - Individual deviations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 7 2014-10-01 2014-10-01 false Individual deviations. 3401.403 Section 3401.403 Federal Acquisition Regulations System DEPARTMENT OF EDUCATION ACQUISITION REGULATION GENERAL ED ACQUISITION REGULATION SYSTEM Deviations 3401.403 Individual deviations. An...

  13. 48 CFR 3401.403 - Individual deviations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 7 2012-10-01 2012-10-01 false Individual deviations. 3401.403 Section 3401.403 Federal Acquisition Regulations System DEPARTMENT OF EDUCATION ACQUISITION REGULATION GENERAL ED ACQUISITION REGULATION SYSTEM Deviations 3401.403 Individual deviations. An...

  14. 48 CFR 3401.403 - Individual deviations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Individual deviations. 3401.403 Section 3401.403 Federal Acquisition Regulations System DEPARTMENT OF EDUCATION ACQUISITION REGULATION GENERAL ED ACQUISITION REGULATION SYSTEM Deviations 3401.403 Individual deviations. An...

  15. 10 CFR 602.4 - Deviations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Deviations. 602.4 Section 602.4 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS EPIDEMIOLOGY AND OTHER HEALTH STUDIES FINANCIAL ASSISTANCE PROGRAM § 602.4 Deviations. (a) Single-case deviations from this part may be authorized in writing by...

  16. 48 CFR 2801.404 - Class deviations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Class deviations. 2801.404 Section 2801.404 Federal Acquisition Regulations System DEPARTMENT OF JUSTICE General DEPARTMENT OF JUSTICE ACQUISITION REGULATIONS SYSTEM Deviations From the FAR and JAR 2801.404 Class deviations....

  17. 48 CFR 2901.404 - Class deviations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Class deviations. 2901.404 Section 2901.404 Federal Acquisition Regulations System DEPARTMENT OF LABOR GENERAL DEPARTMENT OF LABOR ACQUISITION REGULATION SYSTEM Deviations From the FAR and DOLAR 2901.404 Class deviations. (a) The...

  18. Age-specific absolute and relative organ weight distributions for Fischer 344 rats.

    PubMed

    Marino, Dale J

    2012-01-01

    The Fischer 344 (F344) rat has been the standard rat strain used in toxicology studies conducted by the National Cancer Institute (NCI) and the National Toxicology Program (NTP). However, the numerous reports published to date on growth, survival, and tumor incidence have not included an overall compilation of organ weight data. Notably, dose-related organ weight effects are endpoints used by regulatory agencies to develop toxicity reference values (TRVs) for use in human health risk assessments. In addition, physiologically-based pharmacokinetic (PBPK) models, which utilize relative organ weights, are increasingly being used to develop TRVs. Because a compilation of organ weights for F344 rats could prove beneficial for TRV development and PBPK modeling, all available absolute and relative organ weight data for untreated control F344 rats were collected from NCI/NTP feed, drinking-water, and inhalation studies in order to develop age-specific distributions. Results showed that organ weights were collected more frequently at 2-wk (59 studies), 3-mo (148 studies), and 15-mo (38 studies) intervals than at other intervals and more frequently from feeding and inhalation than from drinking-water studies. Liver, right kidney, lung, heart, thymus, and brain weights were most frequently collected. From the collected data, the mean and standard deviation for absolute and relative organ weights were calculated. Findings showed age-related increases in absolute weights and decreases in relative weights for brain, liver, right kidney, lung, heart, thyroid, and right testis. The results suggest a general variability trend in absolute organ weights of brain < right testis < heart < right kidney < liver < lung < thymus < thyroid.

  19. Estimating Absolute Site Effects

    SciTech Connect

    Malagnini, L; Mayeda, K M; Akinci, A; Bragato, P L

    2004-07-15

    The authors use previously determined direct-wave attenuation functions as well as stable, coda-derived source excitation spectra to isolate the absolute S-wave site effect for the horizontal and vertical components of weak ground motion. They used selected stations in the seismic network of the eastern Alps, and find the following: (1) all ''hard rock'' sites exhibited deamplification phenomena due to absorption at frequencies ranging between 0.5 and 12 Hz (the available bandwidth), on both the horizontal and vertical components; (2) ''hard rock'' site transfer functions showed large variability at high-frequency; (3) vertical-motion site transfer functions show strong frequency-dependence, and (4) H/V spectral ratios do not reproduce the characteristics of the true horizontal site transfer functions; (5) traditional, relative site terms obtained by using reference ''rock sites'' can be misleading in inferring the behaviors of true site transfer functions, since most rock sites have non-flat responses due to shallow heterogeneities resulting from varying degrees of weathering. They also use their stable source spectra to estimate total radiated seismic energy and compare against previous results. they find that the earthquakes in this region exhibit non-constant dynamic stress drop scaling which gives further support for a fundamental difference in rupture dynamics between small and large earthquakes. To correct the vertical and horizontal S-wave spectra for attenuation, they used detailed regional attenuation functions derived by Malagnini et al. (2002) who determined frequency-dependent geometrical spreading and Q for the region. These corrections account for the gross path effects (i.e., all distance-dependent effects), although the source and site effects are still present in the distance-corrected spectra. The main goal of this study is to isolate the absolute site effect (as a function of frequency) by removing the source spectrum (moment-rate spectrum) from

  20. Absolute vs. relative machine strength as predictors of function in older adults.

    PubMed

    Knutzen, Kathleen M; Brilla, Lorraine; Caine, Dennis; Chalmers, Gordon; Gunter, Kathy; Schot, Philip

    2002-11-01

    This study examined the relationship between absolute and relative (1 repetition maximum/LBM) strength vs. 13 different functional measurements in 143 older adults (mean = 70.28, standard deviation = 7.90 years). Strength for 11 machine lifts was determined using a predicted 1-repetition maximal strength measurement. Zero-order correlation results between absolute and relative strength vs. function measures demonstrated very weak to moderate correlations in the range of 0.02-0.57 and 0.01-0.44, respectively, with the lowest correlations present between strength and balance measures and the highest correlations present between strength and the carrying task (p absolute and relative strength measures accounting for only 3-38% and 3-33% of the various functional measures, respectively. This study identified specific strength measurements that contribute to the variance in a functional task but also clearly indicated that strength alone cannot serve as a predictor of function in older adults.

  1. Cosmic backgrounds of relic gravitons and their absolute normalization

    NASA Astrophysics Data System (ADS)

    Giovannini, Massimo

    2014-11-01

    Provided the consistency relations are not violated, the recent BICEP2 observations pin down the absolute normalization, the spectral slope and the maximal frequency of the cosmic graviton background produced during inflation. The properly normalized spectra are hereby computed from the lowest frequencies (of the order of the present Hubble rate) up to the highest frequency range in the GHz region. Deviations from the conventional paradigm cannot be excluded and are examined by allowing for different physical possibilities including, in particular, a running of the tensor spectral index, an explicit breaking of the consistency relations and a spike in the high-frequency tail of the spectrum coming either from a post-inflationary phase dominated by a stiff fluid or from the contribution of waterfall fields in a hybrid inflationary context. The direct determinations of the tensor to scalar ratio at low frequencies, if confirmed by the forthcoming observations, will also affect and constrain the high-frequency uncertainties. The limits on the cosmic graviton backgrounds coming from wide-band interferometers (such as LIGO/Virgo, LISA and BBO/DECIGO) together with a more accurate scrutiny of the tensor B-mode polarization at low frequencies will set direct bounds on the post-inflationary evolution and on other unconventional completions of the standard lore.

  2. Teaching Standard Deviation by Building from Student Invention

    ERIC Educational Resources Information Center

    Day, James; Nakahara, Hiroko; Bonn, Doug

    2010-01-01

    First-year physics laboratories are often driven by a mix of goals that includes the illustration or discovery of basic physics principles and a myriad of technical skills involving specific equipment, data analysis, and report writing. The sheer number of such goals seems guaranteed to produce cognitive overload, even when highly detailed…

  3. Teaching Standard Deviation by Building from Student Invention

    NASA Astrophysics Data System (ADS)

    Day, James; Nakahara, Hiroko; Bonn, Doug

    2010-11-01

    First-year physics laboratories are often driven by a mix of goals that includes the illustration or discovery of basic physics principles and a myriad of technical skills involving specific equipment, data analysis, and report writing. The sheer number of such goals seems guaranteed to produce cognitive overload, even when highly detailed "cookbook" instructions are given. Recent studies indicate that this approach leaves students with a poor conceptual understanding of one of the most important features of laboratory physics and of the real world of science, in general: the development of an understanding of the nature of measurement and its attendant uncertainty . While students might be able to reproduce certain technical manipulations of data, as novice thinkers they lack the mental scaffolding that allows an expert to organize and apply this knowledge.2,3 Our goal is to put novices on the path to expertise, so that they will be able to transfer their knowledge to novel situations.

  4. Spectral Relative Standard Deviation: A Practical Benchmark in Metabolomics

    EPA Science Inventory

    Metabolomics datasets, by definition, comprise of measurements of large numbers of metabolites. Both technical (analytical) and biological factors will induce variation within these measurements that is not consistent across all metabolites. Consequently, criteria are required to...

  5. Deviation from Standard Inflationary Cosmology and the Problems in Ekpyrosis

    NASA Astrophysics Data System (ADS)

    Tseng, Chien-Yao

    There are two competing models of our universe right now. One is Big Bang with inflation cosmology. The other is the cyclic model with ekpyrotic phase in each cycle. This paper is divided into two main parts according to these two models. In the first part, we quantify the potentially observable effects of a small violation of translational invariance during inflation, as characterized by the presence of a preferred point, line, or plane. We explore the imprint such a violation would leave on the cosmic microwave background anisotropy, and provide explicit formulas for the expected amplitudes ( alma*l'm') of the spherical-harmonic coefficients. We then provide a model and study the two-point correlation of a massless scalar (the inflaton) when the stress tensor contains the energy density from an infinitely long straight cosmic string in addition to a cosmological constant. Finally, we discuss if inflation can reconcile with the Liouville's theorem as far as the fine-tuning problem is concerned. In the second part, we find several problems in the cyclic/ekpyrotic cosmology. First of all, quantum to classical transition would not happen during an ekpyrotic phase even for superhorizon modes, and therefore the fluctuations cannot be interpreted as classical. This implies the prediction of scale-free power spectrum in ekpyrotic/cyclic universe model requires more inspection. Secondly, we find that the usual mechanism to solve fine-tuning problems is not compatible with eternal universe which contains infinitely many cycles in both direction of time. Therefore, all fine-tuning problems including the flatness problem still asks for an explanation in any generic cyclic models.

  6. Absolute method of measuring magnetic susceptibility

    USGS Publications Warehouse

    Thorpe, A.; Senftle, F.E.

    1959-01-01

    An absolute method of standardization and measurement of the magnetic susceptibility of small samples is presented which can be applied to most techniques based on the Faraday method. The fact that the susceptibility is a function of the area under the curve of sample displacement versus distance of the magnet from the sample, offers a simple method of measuring the susceptibility without recourse to a standard sample. Typical results on a few substances are compared with reported values, and an error of less than 2% can be achieved. ?? 1959 The American Institute of Physics.

  7. Absolute cavity pyrgeometer

    DOEpatents

    Reda, Ibrahim

    2013-10-29

    Implementations of the present disclosure involve an apparatus and method to measure the long-wave irradiance of the atmosphere or long-wave source. The apparatus may involve a thermopile, a concentrator and temperature controller. The incoming long-wave irradiance may be reflected from the concentrator to a thermopile receiver located at the bottom of the concentrator to receive the reflected long-wave irradiance. In addition, the thermopile may be thermally connected to a temperature controller to control the device temperature. Through use of the apparatus, the long-wave irradiance of the atmosphere may be calculated from several measurements provided by the apparatus. In addition, the apparatus may provide an international standard of pyrgeometers' calibration that is traceable back to the International System of Units (SI) rather than to a blackbody atmospheric simulator.

  8. Absolute Radiation Thermometry in the NIR

    NASA Astrophysics Data System (ADS)

    Bünger, L.; Taubert, R. D.; Gutschwager, B.; Anhalt, K.; Briaudeau, S.; Sadli, M.

    2017-04-01

    A near infrared (NIR) radiation thermometer (RT) for temperature measurements in the range from 773 K up to 1235 K was characterized and calibrated in terms of the "Mise en Pratique for the definition of the Kelvin" (MeP-K) by measuring its absolute spectral radiance responsivity. Using Planck's law of thermal radiation allows the direct measurement of the thermodynamic temperature independently of any ITS-90 fixed-point. To determine the absolute spectral radiance responsivity of the radiation thermometer in the NIR spectral region, an existing PTB monochromator-based calibration setup was upgraded with a supercontinuum laser system (0.45 μm to 2.4 μm) resulting in a significantly improved signal-to-noise ratio. The RT was characterized with respect to its nonlinearity, size-of-source effect, distance effect, and the consistency of its individual temperature measuring ranges. To further improve the calibration setup, a new tool for the aperture alignment and distance measurement was developed. Furthermore, the diffraction correction as well as the impedance correction of the current-to-voltage converter is considered. The calibration scheme and the corresponding uncertainty budget of the absolute spectral responsivity are presented. A relative standard uncertainty of 0.1 % (k=1) for the absolute spectral radiance responsivity was achieved. The absolute radiometric calibration was validated at four temperature values with respect to the ITS-90 via a variable temperature heatpipe blackbody (773 K ...1235 K) and at a gold fixed-point blackbody radiator (1337.33 K).

  9. Absolute Isotopic Abundance Ratios and Atomic Weight of a Reference Sample of Nickel

    PubMed Central

    Gramlich, J. W.; Machlan, L. A.; Barnes, I. L.; Paulsen, P. J.

    1989-01-01

    Absolute values have been obtained for the isotopic abundance ratios of a reference sample of nickel (Standard Reference Material 986), using thermal ionization mass spectrometry. Samples of known isotopic composition, prepared from nearly isotopically pure separated nickel isotopes, were used to calibrate the mass spectrometers. The resulting absolute isotopic ratios are: 58Ni/60Ni=2.596061±0.000728, 61Ni/60Ni=0.043469±0.000015,62Ni/60Ni=0.138600±0.000045, and 64Ni/60Ni=0.035295±0.000024, which yield atom percents of 58Ni=68.076886 ±0.005919, 60Ni = 26.223146±0.005144,61Ni=1.139894±0.000433, 62Ni =3.634528±0.001142, and 64Ni =0.925546±0.000599. The atomic weight calculated from this isotopic composition is 58.693353 ±0.000147. The indicated uncertainties are overall limits of error based on two standard deviations of the mean and allowances for the effects of known sources of possible systematic error. PMID:28053421

  10. From Hubble's NGSL to Absolute Fluxes

    NASA Technical Reports Server (NTRS)

    Heap, Sara R.; Lindler, Don

    2012-01-01

    Hubble's Next Generation Spectral Library (NGSL) consists of R-l000 spectra of 374 stars of assorted temperature, gravity, and metallicity. Each spectrum covers the wavelength range, 0.18-1.00 microns. The library can be viewed and/or downloaded from the website, http://archive.stsci.edu/prepds/stisngsll. Stars in the NGSL are now being used as absolute flux standards at ground-based observatories. However, the uncertainty in the absolute flux is about 2%, which does not meet the requirements of dark-energy surveys. We are therefore developing an observing procedure that should yield fluxes with uncertainties less than 1 % and will take part in an HST proposal to observe up to 15 stars using this new procedure.

  11. 10 CFR 609.18 - Deviations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Deviations. 609.18 Section 609.18 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS LOAN GUARANTEES FOR PROJECTS THAT EMPLOY INNOVATIVE TECHNOLOGIES § 609.18 Deviations. To the extent that such requirements are not specified by the Act or...

  12. 34 CFR 74.4 - Deviations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 34 Education 1 2012-07-01 2012-07-01 false Deviations. 74.4 Section 74.4 Education Office of the Secretary, Department of Education ADMINISTRATION OF GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS General § 74.4 Deviations. The Secretary,...

  13. 34 CFR 74.4 - Deviations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 34 Education 1 2013-07-01 2013-07-01 false Deviations. 74.4 Section 74.4 Education Office of the Secretary, Department of Education ADMINISTRATION OF GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS General § 74.4 Deviations. The Secretary,...

  14. 34 CFR 74.4 - Deviations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 34 Education 1 2014-07-01 2014-07-01 false Deviations. 74.4 Section 74.4 Education Office of the Secretary, Department of Education ADMINISTRATION OF GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS General § 74.4 Deviations. The Secretary,...

  15. 34 CFR 74.4 - Deviations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Deviations. 74.4 Section 74.4 Education Office of the Secretary, Department of Education ADMINISTRATION OF GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS General § 74.4 Deviations. The Secretary,...

  16. 34 CFR 74.4 - Deviations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 34 Education 1 2011-07-01 2011-07-01 false Deviations. 74.4 Section 74.4 Education Office of the Secretary, Department of Education ADMINISTRATION OF GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS General § 74.4 Deviations. The Secretary,...

  17. Alternating Skew Deviation from Traumatic Intracranial Hypotension

    PubMed Central

    Moster, Stephen J.; Moster, Mark L.

    2014-01-01

    Abstract A 56-year-old woman developed progressive headache, mental status changes, and diplopia after trauma. She was diagnosed with alternating skew deviation caused by intracranial hypotension. This is the first case of alternating skew deviation reported from intracranial hypotension and perhaps a differential pressure between intracranial and intraspinal spaces plays a role in the development of these findings. PMID:27928294

  18. 22 CFR 518.4 - Deviations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 2 2013-04-01 2009-04-01 true Deviations. 518.4 Section 518.4 Foreign Relations BROADCASTING BOARD OF GOVERNORS UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS General § 518.4 Deviations....

  19. 22 CFR 518.4 - Deviations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Deviations. 518.4 Section 518.4 Foreign Relations BROADCASTING BOARD OF GOVERNORS UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS General § 518.4 Deviations....

  20. 22 CFR 145.4 - Deviations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Deviations. 145.4 Section 145.4 Foreign Relations DEPARTMENT OF STATE CIVIL RIGHTS GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS General § 145.4 Deviations. The Office of Management...

  1. 22 CFR 145.4 - Deviations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 22 Foreign Relations 1 2014-04-01 2014-04-01 false Deviations. 145.4 Section 145.4 Foreign Relations DEPARTMENT OF STATE CIVIL RIGHTS GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS General § 145.4 Deviations. The Office of Management...

  2. 22 CFR 145.4 - Deviations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 22 Foreign Relations 1 2013-04-01 2013-04-01 false Deviations. 145.4 Section 145.4 Foreign Relations DEPARTMENT OF STATE CIVIL RIGHTS GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS General § 145.4 Deviations. The Office of Management...

  3. 22 CFR 518.4 - Deviations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 22 Foreign Relations 2 2012-04-01 2009-04-01 true Deviations. 518.4 Section 518.4 Foreign Relations BROADCASTING BOARD OF GOVERNORS UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS General § 518.4 Deviations....

  4. 22 CFR 518.4 - Deviations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Deviations. 518.4 Section 518.4 Foreign Relations BROADCASTING BOARD OF GOVERNORS UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS General § 518.4 Deviations....

  5. 22 CFR 145.4 - Deviations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Deviations. 145.4 Section 145.4 Foreign Relations DEPARTMENT OF STATE CIVIL RIGHTS GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS General § 145.4 Deviations. The Office of Management...

  6. 48 CFR 1480.403 - Deviations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... authorize a deviation for an IA acquisition: For a proposed contract action . . . The following official may authorize a deviation . . . Exceeding $25,000 but not exceeding $550,000 The CCO (or the IA Procurement Chief, absent a CCO). Exceeding $550,000 but not exceeding $11.5 million IA Competition...

  7. 48 CFR 2001.403 - Individual deviations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Individual deviations. 2001.403 Section 2001.403 Federal Acquisition Regulations System NUCLEAR REGULATORY COMMISSION GENERAL NUCLEAR REGULATORY COMMISSION ACQUISITION REGULATION SYSTEM Deviations From the FAR and the NRCAR...

  8. 48 CFR 2001.403 - Individual deviations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Individual deviations. 2001.403 Section 2001.403 Federal Acquisition Regulations System NUCLEAR REGULATORY COMMISSION GENERAL NUCLEAR REGULATORY COMMISSION ACQUISITION REGULATION SYSTEM Deviations From the FAR and the NRCAR...

  9. 48 CFR 2001.403 - Individual deviations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Individual deviations. 2001.403 Section 2001.403 Federal Acquisition Regulations System NUCLEAR REGULATORY COMMISSION GENERAL NUCLEAR REGULATORY COMMISSION ACQUISITION REGULATION SYSTEM Deviations From the FAR and the NRCAR...

  10. 48 CFR 2001.404 - Class deviations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 6 2013-10-01 2013-10-01 false Class deviations. 2001.404 Section 2001.404 Federal Acquisition Regulations System NUCLEAR REGULATORY COMMISSION GENERAL NUCLEAR REGULATORY COMMISSION ACQUISITION REGULATION SYSTEM Deviations From the FAR and the NRCAR 2001.404...

  11. 48 CFR 2001.403 - Individual deviations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Individual deviations. 2001.403 Section 2001.403 Federal Acquisition Regulations System NUCLEAR REGULATORY COMMISSION GENERAL NUCLEAR REGULATORY COMMISSION ACQUISITION REGULATION SYSTEM Deviations From the FAR and the NRCAR...

  12. 48 CFR 2001.404 - Class deviations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 6 2012-10-01 2012-10-01 false Class deviations. 2001.404 Section 2001.404 Federal Acquisition Regulations System NUCLEAR REGULATORY COMMISSION GENERAL NUCLEAR REGULATORY COMMISSION ACQUISITION REGULATION SYSTEM Deviations From the FAR and the NRCAR 2001.404...

  13. 48 CFR 2001.404 - Class deviations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Class deviations. 2001.404 Section 2001.404 Federal Acquisition Regulations System NUCLEAR REGULATORY COMMISSION GENERAL NUCLEAR REGULATORY COMMISSION ACQUISITION REGULATION SYSTEM Deviations From the FAR and the NRCAR 2001.404...

  14. 48 CFR 2001.403 - Individual deviations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Individual deviations. 2001.403 Section 2001.403 Federal Acquisition Regulations System NUCLEAR REGULATORY COMMISSION GENERAL NUCLEAR REGULATORY COMMISSION ACQUISITION REGULATION SYSTEM Deviations From the FAR and the NRCAR...

  15. 48 CFR 2001.404 - Class deviations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 6 2014-10-01 2014-10-01 false Class deviations. 2001.404 Section 2001.404 Federal Acquisition Regulations System NUCLEAR REGULATORY COMMISSION GENERAL NUCLEAR REGULATORY COMMISSION ACQUISITION REGULATION SYSTEM Deviations From the FAR and the NRCAR 2001.404...

  16. 48 CFR 2001.404 - Class deviations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 6 2011-10-01 2011-10-01 false Class deviations. 2001.404 Section 2001.404 Federal Acquisition Regulations System NUCLEAR REGULATORY COMMISSION GENERAL NUCLEAR REGULATORY COMMISSION ACQUISITION REGULATION SYSTEM Deviations From the FAR and the NRCAR 2001.404...

  17. 20 CFR 435.4 - Deviations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Deviations. 435.4 Section 435.4 Employees' Benefits SOCIAL SECURITY ADMINISTRATION UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH... General § 435.4 Deviations. The Office of Management and Budget (OMB) may grant exceptions for classes...

  18. 20 CFR 435.4 - Deviations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Deviations. 435.4 Section 435.4 Employees' Benefits SOCIAL SECURITY ADMINISTRATION UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH... General § 435.4 Deviations. The Office of Management and Budget (OMB) may grant exceptions for classes...

  19. 20 CFR 435.4 - Deviations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Deviations. 435.4 Section 435.4 Employees' Benefits SOCIAL SECURITY ADMINISTRATION UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH... General § 435.4 Deviations. The Office of Management and Budget (OMB) may grant exceptions for classes...

  20. 20 CFR 435.4 - Deviations.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Deviations. 435.4 Section 435.4 Employees' Benefits SOCIAL SECURITY ADMINISTRATION UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH... General § 435.4 Deviations. The Office of Management and Budget (OMB) may grant exceptions for classes...

  1. 20 CFR 435.4 - Deviations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Deviations. 435.4 Section 435.4 Employees' Benefits SOCIAL SECURITY ADMINISTRATION UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH... General § 435.4 Deviations. The Office of Management and Budget (OMB) may grant exceptions for classes...

  2. 10 CFR 800.204 - Deviations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 4 2011-01-01 2011-01-01 false Deviations. 800.204 Section 800.204 Energy DEPARTMENT OF ENERGY LOANS FOR BID OR PROPOSAL PREPARATION BY MINORITY BUSINESS ENTERPRISES SEEKING DOE CONTRACTS AND ASSISTANCE Loans § 800.204 Deviations. (a) To the extent consistent with the Act, relevant...

  3. 10 CFR 800.204 - Deviations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Deviations. 800.204 Section 800.204 Energy DEPARTMENT OF ENERGY LOANS FOR BID OR PROPOSAL PREPARATION BY MINORITY BUSINESS ENTERPRISES SEEKING DOE CONTRACTS AND ASSISTANCE Loans § 800.204 Deviations. (a) To the extent consistent with the Act, relevant...

  4. 10 CFR 800.204 - Deviations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Deviations. 800.204 Section 800.204 Energy DEPARTMENT OF ENERGY LOANS FOR BID OR PROPOSAL PREPARATION BY MINORITY BUSINESS ENTERPRISES SEEKING DOE CONTRACTS AND ASSISTANCE Loans § 800.204 Deviations. (a) To the extent consistent with the Act, relevant...

  5. 10 CFR 800.204 - Deviations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 4 2012-01-01 2012-01-01 false Deviations. 800.204 Section 800.204 Energy DEPARTMENT OF ENERGY LOANS FOR BID OR PROPOSAL PREPARATION BY MINORITY BUSINESS ENTERPRISES SEEKING DOE CONTRACTS AND ASSISTANCE Loans § 800.204 Deviations. (a) To the extent consistent with the Act, relevant...

  6. 10 CFR 800.204 - Deviations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 4 2014-01-01 2014-01-01 false Deviations. 800.204 Section 800.204 Energy DEPARTMENT OF ENERGY LOANS FOR BID OR PROPOSAL PREPARATION BY MINORITY BUSINESS ENTERPRISES SEEKING DOE CONTRACTS AND ASSISTANCE Loans § 800.204 Deviations. (a) To the extent consistent with the Act, relevant...

  7. 48 CFR 1401.404 - Class deviations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Class deviations. 1401.404 Section 1401.404 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL DEPARTMENT OF THE INTERIOR ACQUISITION REGULATION SYSTEM Deviations from the FAR and DIAR 1401.404 Class...

  8. 48 CFR 3001.404 - Class deviations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Class deviations. 3001.404 Section 3001.404 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND SECURITY, HOMELAND SECURITY ACQUISITION REGULATION (HSAR) GENERAL FEDERAL ACQUISITION REGULATIONS SYSTEM Deviations from the FAR and...

  9. Cryogenic, Absolute, High Pressure Sensor

    NASA Technical Reports Server (NTRS)

    Chapman, John J. (Inventor); Shams. Qamar A. (Inventor); Powers, William T. (Inventor)

    2001-01-01

    A pressure sensor is provided for cryogenic, high pressure applications. A highly doped silicon piezoresistive pressure sensor is bonded to a silicon substrate in an absolute pressure sensing configuration. The absolute pressure sensor is bonded to an aluminum nitride substrate. Aluminum nitride has appropriate coefficient of thermal expansion for use with highly doped silicon at cryogenic temperatures. A group of sensors, either two sensors on two substrates or four sensors on a single substrate are packaged in a pressure vessel.

  10. Embedded north-seeker for automatic absolute magnetic DI measurements

    NASA Astrophysics Data System (ADS)

    Gonsette, Alexandre; Rasson, Jean

    2014-05-01

    In magnetic observatory Earth magnetic field is recorded with a resolution of 0.1nT for 1min sampling (new standards impose 1pT for 1s sampling). The method universally adopted for measuring it is a combination of three instruments. Vectorial magnetometer (variometer) records variations of the three components around a reference value or a baseline. A proton or an overhauser magnetometer is an absolute instrument able to measure the modulus of the field and used to determine the F component baseline of the variometer. The declination and inclination baselines require a manual procedure to be computed. An operator manipulates a non-magnetic theodolite (also called a DIFlux) to measure the D and I angles in different configurations with a resolution of a few arcsec. The AutoDIF is a non-magnetic automatic DIFlux using the same protocol as the manual procedure. The declination defined according to the true north is determined by means of a target pointing system. Even if the technique is fast and accurate, it becomes problematic in case of unmanned deployment. In particular the area between the target and the DIFlux is out of control. Snow storm, fog, vegetation or condensation on windows are examples of perturbation preventing for finding the target. It is obvious in case of (future) seafloor observatories. A FOG based north-seeker has been implemented and mounted on the AutoDIF. The first results using a low cost gyro don't meet the Intermagnet specifications yet but are however hopeful. A 0.1° standard deviation has been reached and statistically reduced to 0.01° after less than two days in laboratory. The magnetic disturbance of the sensor is taken into account and compensated by the measurement protocol.

  11. Monochromator-Based Absolute Calibration of Radiation Thermometers

    NASA Astrophysics Data System (ADS)

    Keawprasert, T.; Anhalt, K.; Taubert, D. R.; Hartmann, J.

    2011-08-01

    A monochromator integrating-sphere-based spectral comparator facility has been developed to calibrate standard radiation thermometers in terms of the absolute spectral radiance responsivity, traceable to the PTB cryogenic radiometer. The absolute responsivity calibration has been improved using a 75 W xenon lamp with a reflective mirror and imaging optics to a relative standard uncertainty at the peak wavelength of approximately 0.17 % ( k = 1). Via a relative measurement of the out-of-band responsivity, the spectral responsivity of radiation thermometers can be fully characterized. To verify the calibration accuracy, the absolutely calibrated radiation thermometer is used to measure Au and Cu freezing-point temperatures and then to compare the obtained results with the values obtained by absolute methods, resulting in T - T 90 values of +52 mK and -50 mK for the gold and copper fixed points, respectively.

  12. System for absolute measurements by interferometric sensors

    NASA Astrophysics Data System (ADS)

    Norton, Douglas A.

    1993-03-01

    The most common problem of interferometric sensors is their inability to measure absolute path imbalance. Presented in this paper is a signal processing system that gives absolute, unambiguous reading of optical path difference for almost any style of interferometric sensor. Key components are a wide band (incoherent) optical source, a polychromator, and FFT electronics. Advantages include no moving parts in the signal processor, no active components at the sensor location, and the use of standard single mode fiber for sensor illumination and signal transmission. Actual absolute path imbalance of the interferometer is determined without using fringe counting or other inferential techniques. The polychromator extracts the interference information that occurs at each discrete wavelength within the spectral band of the optical source. The signal processing consists of analog and digital filtering, Fast Fourier analysis, and a peak detection and interpolation algorithm. This system was originally designed for use in a remote pressure sensing application that employed a totally passive fiber optic interferometer. A performance qualification was made using a Fabry-Perot interferometer and a commercially available laser interferometer to measure the reference displacement.

  13. Chemical composition of French mimosa absolute oil.

    PubMed

    Perriot, Rodolphe; Breme, Katharina; Meierhenrich, Uwe J; Carenini, Elise; Ferrando, Georges; Baldovini, Nicolas

    2010-02-10

    Since decades mimosa (Acacia dealbata) absolute oil has been used in the flavor and perfume industry. Today, it finds an application in over 80 perfumes, and its worldwide industrial production is estimated five tons per year. Here we report on the chemical composition of French mimosa absolute oil. Straight-chain analogues from C6 to C26 with different functional groups (hydrocarbons, esters, aldehydes, diethyl acetals, alcohols, and ketones) were identified in the volatile fraction. Most of them are long-chain molecules: (Z)-heptadec-8-ene, heptadecane, nonadecane, and palmitic acid are the most abundant, and constituents such as 2-phenethyl alcohol, methyl anisate, and ethyl palmitate are present in smaller amounts. The heavier constituents were mainly triterpenoids such as lupenone and lupeol, which were identified as two of the main components. (Z)-Heptadec-8-ene, lupenone, and lupeol were quantified by GC-MS in SIM mode using external standards and represents 6%, 20%, and 7.8% (w/w) of the absolute oil. Moreover, odorant compounds were extracted by SPME and analyzed by GC-sniffing leading to the perception of 57 odorant zones, of which 37 compounds were identified by their odorant description, mass spectrum, retention index, and injection of the reference compound.

  14. 38 CFR 49.4 - Deviations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... NON-PROFIT ORGANIZATIONS General § 49.4 Deviations. The Office of Management and Budget (OMB) may..., which are statutory. Exceptions on a case-by-case basis may also be made by Federal awarding...

  15. 32 CFR 32.4 - Deviations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... class deviations. (1) For classes of awards other than small awards, the Director of Defense Research... part: (i) With the written concurrence of the Office of the Management and Budget (OMB). The DDR&E,...

  16. 32 CFR 32.4 - Deviations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... class deviations. (1) For classes of awards other than small awards, the Director of Defense Research... part: (i) With the written concurrence of the Office of the Management and Budget (OMB). The DDR&E,...

  17. 48 CFR 201.403 - Individual deviations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    .... 2341(2)), or with United Nations or NATO organizations; and (ii) Such governments or organizations will...). (2) Contracting officers outside the United States may deviate from prescribed nonstatutory FAR...

  18. Role of Extracorporeal Septoplasty in Deviated Noses.

    PubMed

    Ghaisas, Virendra; Parab, Sapna Ramkrishna

    2015-09-01

    Severe gross septal deviations present big surgical challenges for operating surgeon. Septal deviations has direct effect on aesthetic and functional part of nose. Correcting septal deviations during rhinoplasty is basic procedure. Extreme deviations of septum especially on dorsal and caudal end of cartilaginous septum are difficult to treat. The classical septoplasty approach becomes unsuitable for such severe deviations. Gubisch has first reported in 1995 about extracorporeal septoplasty. To report the experience of Extracorporeal septoplasty and the complication rates with the technique. Retrospective study of 112 patients who underwent extracorporeal septoplasty in primary rhinoplasty from May 2009 to June 2014. Patient's pre and postoperatively evaluation was done by photographs, nasal endoscopy and subjective by symptoms evaluation satisfaction scale 6 and 12 months postoperatively. Nasal endoscopy revealed significant improvement in nasal airway and nasal valve and subjective evaluation satisfaction score was very encouraging. Complications like septal perforation, bleeding, aesthetic complications were minimal (9 %) On basis of results obtained, shows that this technique, increases patients nasal airway and aesthetic look of the patients. Irrespective of extreme nasal deviations.

  19. Absolute magnitudes of asteroids and a revision of asteroid albedo estimates from WISE thermal observations

    NASA Astrophysics Data System (ADS)

    Pravec, Petr; Harris, Alan W.; Kušnirák, Peter; Galád, Adrián; Hornoch, Kamil

    2012-09-01

    We obtained estimates of the Johnson V absolute magnitudes (H) and slope parameters (G) for 583 main-belt and near-Earth asteroids observed at Ondřejov and Table Mountain Observatory from 1978 to 2011. Uncertainties of the absolute magnitudes in our sample are <0.21 mag, with a median value of 0.10 mag. We compared the H data with absolute magnitude values given in the MPCORB, Pisa AstDyS and JPL Horizons orbit catalogs. We found that while the catalog absolute magnitudes for large asteroids are relatively good on average, showing only little biases smaller than 0.1 mag, there is a systematic offset of the catalog values for smaller asteroids that becomes prominent in a range of H greater than ∼10 and is particularly big above H ∼ 12. The mean (Hcatalog - H) value is negative, i.e., the catalog H values are systematically too bright. This systematic negative offset of the catalog values reaches a maximum around H = 14 where the mean (Hcatalog - H) is -0.4 to -0.5. We found also smaller correlations of the offset of the catalog H values with taxonomic types and with lightcurve amplitude, up to ∼0.1 mag or less. We discuss a few possible observational causes for the observed correlations, but the reason for the large bias of the catalog absolute magnitudes peaking around H = 14 is unknown; we suspect that the problem lies in the magnitude estimates reported by asteroid surveys. With our photometric H and G data, we revised the preliminary WISE albedo estimates made by Masiero et al. (Masired, J.R. et al. [2011]. Astrophys. J. 741, 68-89) and Mainzer et al. (Mainzer, A. et al. [2011b]. Astrophys. J. 743, 156-172) for asteroids in our sample. We found that the mean geometric albedo of Tholen/Bus/DeMeo C/G/B/F/P/D types with sizes of 25-300 km is pV = 0.057 with the standard deviation (dispersion) of the sample of 0.013 and the mean albedo of S/A/L types with sizes 0.6-200 km is 0.197 with the standard deviation of the sample of 0.051. The standard errors of the

  20. Absolute classification with unsupervised clustering

    NASA Technical Reports Server (NTRS)

    Jeon, Byeungwoo; Landgrebe, D. A.

    1992-01-01

    An absolute classification algorithm is proposed in which the class definition through training samples or otherwise is required only for a particular class of interest. The absolute classification is considered as a problem of unsupervised clustering when one cluster is known initially. The definitions and statistics of the other classes are automatically developed through the weighted unsupervised clustering procedure, which is developed to keep the cluster corresponding to the class of interest from losing its identity as the class of interest. Once all the classes are developed, a conventional relative classifier such as the maximum-likelihood classifier is used in the classification.

  1. Simple absolute quantification method correcting for quantitative PCR efficiency variations for microbial community samples.

    PubMed

    Brankatschk, Robert; Bodenhausen, Natacha; Zeyer, Josef; Bürgmann, Helmut

    2012-06-01

    Real-time quantitative PCR (qPCR) is a widely used technique in microbial community analysis, allowing the quantification of the number of target genes in a community sample. Currently, the standard-curve (SC) method of absolute quantification is widely employed for these kinds of analysis. However, the SC method assumes that the amplification efficiency (E) is the same for both the standard and the sample target template. We analyzed 19 bacterial strains and nine environmental samples in qPCR assays, targeting the nifH and 16S rRNA genes. The E values of the qPCRs differed significantly, depending on the template. This has major implications for the quantification. If the sample and standard differ in their E values, quantification errors of up to orders of magnitude are possible. To address this problem, we propose and test the one-point calibration (OPC) method for absolute quantification. The OPC method corrects for differences in E and was derived from the ΔΔC(T) method with correction for E, which is commonly used for relative quantification in gene expression studies. The SC and OPC methods were compared by quantifying artificial template mixtures from Geobacter sulfurreducens (DSM 12127) and Nostoc commune (Culture Collection of Algae and Protozoa [CCAP] 1453/33), which differ in their E values. While the SC method deviated from the expected nifH gene copy number by 3- to 5-fold, the OPC method quantified the template mixtures with high accuracy. Moreover, analyzing environmental samples, we show that even small differences in E between the standard and the sample can cause significant differences between the copy numbers calculated by the SC and the OPC methods.

  2. The importance of calculating absolute rather than relative fracture risk.

    PubMed

    Tucker, Graeme; Metcalfe, Andrew; Pearce, Charles; Need, Allan G; Dick, Ian M; Prince, Richard L; Nordin, B E Christopher

    2007-12-01

    The relation between fracture risk and bone mineral density (BMD) is commonly expressed as a multiplicative factor which is said to represent the increase in risk for each standard deviation fall in BMD. This practice assumes that risk increases multiplicatively with each unit fall in bone density, which is not correct. Although odds increase multiplicatively, absolute risk, which lies between 0 and 1, cannot do so though it can be derived from odds by the term Odds/(1+Odds). This concept is illustrated in a prospective study of 1098 women over age 69 followed for 6 years in a calcium trial in which hip BMD was measured in the second year. 304 Women (27.6%) had prevalent fractures and 198 (18.1%) incident fractures with a significant association between them (P 0.005). Age-adjusted hip BMD and T-score were significantly lower in those with prevalent fractures than in those without (P 0.003) and significantly lower in those with incident fractures than in those without (P 0.001). When the data were analysed by univariate logistic regression, the fracture odds at zero T-score were 0.130 and the rise in odds for each unit fall in hip T-score was 1.55. When these odds were converted to risks, there was a progressive divergence between odds and risk at T-scores below zero. Multiple logistic regression yielded significant odds ratios of 1.47 for each 5-year increase in age, 1.47 for prevalent fracture and 1.49 for each unit fall in hip T-score. Calcium therapy was not significant. Poisson regression, logistic regression and Cox's proportional hazards yielded very similar outcomes when converted into absolute risks. A nomogram was constructed to enable clinicians to estimate the approximate 6-year fracture risk from hip T-score, age and prevalent fracture which can probably be applied (with appropriate correction) to men as well as to women. We conclude that multiplicative factors can be applied to odds but not to risk and that multipliers of risk tend to overstate the

  3. Achieving Climate Change Absolute Accuracy in Orbit

    NASA Technical Reports Server (NTRS)

    Wielicki, Bruce A.; Young, D. F.; Mlynczak, M. G.; Thome, K. J; Leroy, S.; Corliss, J.; Anderson, J. G.; Ao, C. O.; Bantges, R.; Best, F.; Bowman, K.; Brindley, H.; Butler, J. J.; Collins, W.; Dykema, J. A.; Doelling, D. R.; Feldman, D. R.; Fox, N.; Huang, X.; Holz, R.; Huang, Y.; Jennings, D.; Jin, Z.; Johnson, D. G.; Jucks, K.; Kato, S.; Kratz, D. P.; Liu, X.; Lukashin, C.; Mannucci, A. J.; Phojanamongkolkij, N.; Roithmayr, C. M.; Sandford, S.; Taylor, P. C.; Xiong, X.

    2013-01-01

    The Climate Absolute Radiance and Refractivity Observatory (CLARREO) mission will provide a calibration laboratory in orbit for the purpose of accurately measuring and attributing climate change. CLARREO measurements establish new climate change benchmarks with high absolute radiometric accuracy and high statistical confidence across a wide range of essential climate variables. CLARREO's inherently high absolute accuracy will be verified and traceable on orbit to Système Internationale (SI) units. The benchmarks established by CLARREO will be critical for assessing changes in the Earth system and climate model predictive capabilities for decades into the future as society works to meet the challenge of optimizing strategies for mitigating and adapting to climate change. The CLARREO benchmarks are derived from measurements of the Earth's thermal infrared spectrum (5-50 micron), the spectrum of solar radiation reflected by the Earth and its atmosphere (320-2300 nm), and radio occultation refractivity from which accurate temperature profiles are derived. The mission has the ability to provide new spectral fingerprints of climate change, as well as to provide the first orbiting radiometer with accuracy sufficient to serve as the reference transfer standard for other space sensors, in essence serving as a "NIST [National Institute of Standards and Technology] in orbit." CLARREO will greatly improve the accuracy and relevance of a wide range of space-borne instruments for decadal climate change. Finally, CLARREO has developed new metrics and methods for determining the accuracy requirements of climate observations for a wide range of climate variables and uncertainty sources. These methods should be useful for improving our understanding of observing requirements for most climate change observations.

  4. A novel absolute displacement measurement technology based on wavenumber resolved low coherence interferometry

    NASA Astrophysics Data System (ADS)

    Zhao, Keqiang; Xie, Fang; Ma, Sen; Wang, Yunzhi; Chen, Liang

    2015-12-01

    This paper proposed a novel absolute displacement measurement technology which is based on the wavenumber spectrum of low coherence interferometry. The signal from a Michelson interferometer, which is derived from a broadband light source, is dispersed by a bulk dispersing grating. The interferometric signal of each wavelength is detected by a linear array charge coupled device (CCD). By transforming the wavelength spectrum of the signal into wavenumber spectrum, absolute displacement can be measured precisely by measuring the wavenumber difference between two neighboring peaks of the wavenumber spectrum. Unlike the normal low coherence interferometric measurement systems (LCIMS) which have to scan the optical path difference (OPD) of the interferometer in order to demodulate the measurand, there is no need of scanning action during the measurement procedure, which not only simplifies the measurement system but also improves the measurement speed greatly. A fiber Bragg grating (FBG) is employed to produce a feedback signal which is used to stabilize the Michelson interferometer so as to obtain high measurement precision. A step height with the calibrated value of 50 μm that is configurated with two gauge blocks is measured by the system. The measurement resolution is 6.03 nm and the standard deviation of 10 times measurement results is 6.8 nm.

  5. Constraining absolute neutrino masses via detection of galactic supernova neutrinos at JUNO

    SciTech Connect

    Lu, Jia-Shu; Cao, Jun; Li, Yu-Feng; Zhou, Shun E-mail: caoj@ihep.ac.cn E-mail: zhoush@ihep.ac.cn

    2015-05-01

    A high-statistics measurement of the neutrinos from a galactic core-collapse supernova is extremely important for understanding the explosion mechanism, and studying the intrinsic properties of neutrinos themselves. In this paper, we explore the possibility to constrain the absolute scale of neutrino masses m{sub ν} via the detection of galactic supernova neutrinos at the Jiangmen Underground Neutrino Observatory (JUNO) with a 20 kiloton liquid-scintillator detector. In assumption of a nearly-degenerate neutrino mass spectrum and a normal mass ordering, the upper bound on the absolute neutrino mass is found to be m{sub ν} < (0.83 ± 0.24) eV at the 95% confidence level for a typical galactic supernova at a distance of 10 kpc, where the mean value and standard deviation are shown to account for statistical fluctuations. For comparison, we find that the bound in the Super-Kamiokande experiment is m{sub ν} < (0.94 ± 0.28) eV at the same confidence level. However, the upper bound will be relaxed when the model parameters characterizing the time structure of supernova neutrino fluxes are not exactly known, and when the neutrino mass ordering is inverted.

  6. Absolute distance measurement with correction of air refractive index by using two-color dispersive interferometry.

    PubMed

    Wu, Hanzhong; Zhang, Fumin; Liu, Tingyang; Li, Jianshuang; Qu, Xinghua

    2016-10-17

    Two-color interferometry is powerful for the correction of the air refractive index especially in the turbulent air over long distance, since the empirical equations could introduce considerable measurement uncertainty if the environmental parameters cannot be measured with sufficient precision. In this paper, we demonstrate a method for absolute distance measurement with high-accuracy correction of air refractive index using two-color dispersive interferometry. The distances corresponding to the two wavelengths can be measured via the spectrograms captured by a CCD camera pair in real time. In the long-term experiment of the correction of air refractive index, the experimental results show a standard deviation of 3.3 × 10-8 for 12-h continuous measurement without the precise knowledge of the environmental conditions, while the variation of the air refractive index is about 2 × 10-6. In the case of absolute distance measurement, the comparison with the fringe counting interferometer shows an agreement within 2.5 μm in 12 m range.

  7. Constraining absolute neutrino masses via detection of galactic supernova neutrinos at JUNO

    SciTech Connect

    Lu, Jia-Shu; Cao, Jun; Li, Yu-Feng; Zhou, Shun

    2015-05-26

    A high-statistics measurement of the neutrinos from a galactic core-collapse supernova is extremely important for understanding the explosion mechanism, and studying the intrinsic properties of neutrinos themselves. In this paper, we explore the possibility to constrain the absolute scale of neutrino masses m{sub ν} via the detection of galactic supernova neutrinos at the Jiangmen Underground Neutrino Observatory (JUNO) with a 20 kiloton liquid-scintillator detector. In assumption of a nearly-degenerate neutrino mass spectrum and a normal mass ordering, the upper bound on the absolute neutrino mass is found to be m{sub ν}<(0.83±0.24) eV at the 95% confidence level for a typical galactic supernova at a distance of 10 kpc, where the mean value and standard deviation are shown to account for statistical fluctuations. For comparison, we find that the bound in the Super-Kamiokande experiment is m{sub ν}<(0.94±0.28) eV at the same confidence level. However, the upper bound will be relaxed when the model parameters characterizing the time structure of supernova neutrino fluxes are not exactly known, and when the neutrino mass ordering is inverted.

  8. Absolute transition probabilities of phosphorus.

    NASA Technical Reports Server (NTRS)

    Miller, M. H.; Roig, R. A.; Bengtson, R. D.

    1971-01-01

    Use of a gas-driven shock tube to measure the absolute strengths of 21 P I lines and 126 P II lines (from 3300 to 6900 A). Accuracy for prominent, isolated neutral and ionic lines is estimated to be 28 to 40% and 18 to 30%, respectively. The data and the corresponding theoretical predictions are examined for conformity with the sum rules.-

  9. Relativistic Absolutism in Moral Education.

    ERIC Educational Resources Information Center

    Vogt, W. Paul

    1982-01-01

    Discusses Emile Durkheim's "Moral Education: A Study in the Theory and Application of the Sociology of Education," which holds that morally healthy societies may vary in culture and organization but must possess absolute rules of moral behavior. Compares this moral theory with current theory and practice of American educators. (MJL)

  10. Absolute Spectrophotometry of 237 Open Cluster Stars

    NASA Astrophysics Data System (ADS)

    Clampitt, L.; Burstein, D.

    1994-12-01

    We present absolute spectrophotometry of 237 stars in 7 nearby open clusters: Hyades, Pleiades, Alpha Persei, Praesepe, Coma Berenices, IC 4665, and M 39. The observations were taken using the Wampler single-channel scanner (Wampler 1966) on the Crossley 0.9m telescope at Lick Observatory from July 1973 through December 1974. 21 bandpasses spanning the spectral range 3500 Angstroms to 7780 Angstroms were observed for each star, with bandwiths ranging from 32Angstroms to 64 Angstroms. Data are standardized to the Hayes--Latham (1975) system. Our measurements are compared to filter colors on the Johnson BV, Stromgren ubvy, and Geneva U V B_1 B_2 V_1 G systems, as well as to spectrophotometry of a few stars published by Gunn, Stryker & Tinsley and in the Spectrophotometric Standards Catalog (Adelman; as distributed by the NSSDC). Both internal and external comparisons to the filter systems indicate a formal statistical accuracy per bandpass of 0.01 to 0.02 mag, with apparent larger ( ~ 0.03 mag) differences in absolute calibration between this data set and existing spectrophotometry. These data will comprise part of the spectrophotometry that will be used to calibrate the Beijing-Arizona-Taipei-Connecticut Color Survey of the Sky (see separate paper by Burstein et al. at this meeting).

  11. Development of a graphite probe calorimeter for absolute clinical dosimetry

    SciTech Connect

    Renaud, James; Seuntjens, Jan; Sarfehnia, Arman; Marchington, David

    2013-02-15

    The aim of this work is to present the numerical design optimization, construction, and experimental proof of concept of a graphite probe calorimeter (GPC) conceived for dose measurement in the clinical environment (U.S. provisional patent 61/652,540). A finite element method (FEM) based numerical heat transfer study was conducted using a commercial software package to explore the feasibility of the GPC and to optimize the shape, dimensions, and materials used in its design. A functioning prototype was constructed inhouse and used to perform dose to water measurements under a 6 MV photon beam at 400 and 1000 MU/min, in a thermally insulated water phantom. Heat loss correction factors were determined using FEM analysis while the radiation field perturbation and the graphite to water absorbed dose conversion factors were calculated using Monte Carlo simulations. The difference in the average measured dose to water for the 400 and 1000 MU/min runs using the TG-51 protocol and the GPC was 0.2% and 1.2%, respectively. Heat loss correction factors ranged from 1.001 to 1.002, while the product of the perturbation and dose conversion factors was calculated to be 1.130. The combined relative uncertainty was estimated to be 1.4%, with the largest contributors being the specific heat capacity of the graphite (type B, 0.8%) and the reproducibility, defined as the standard deviation of the mean measured dose (type A, 0.6%). By establishing the feasibility of using the GPC as a practical clinical absolute photon dosimeter, this work lays the foundation for further device enhancements, including the development of an isothermal mode of operation and an overall miniaturization, making it potentially suitable for use in small and composite radiation fields. It is anticipated that, through the incorporation of isothermal stabilization provided by temperature controllers, a subpercent overall uncertainty will be achieved.

  12. Absolute, Extreme-Ultraviolet, Solar Spectral Irradiance Monitor (AESSIM)

    NASA Technical Reports Server (NTRS)

    Huber, Martin C. E.; Smith, Peter L.; Parkinson, W. H.; Kuehne, M.; Kock, M.

    1988-01-01

    AESSIM, the Absolute, Extreme-Ultraviolet, Solar Spectral Irradiance Monitor, is designed to measure the absolute solar spectral irradiance at extreme-ultraviolet (EUV) wavelengths. The data are required for studies of the processes that occur in the earth's upper atmosphere and for predictions of atmospheric drag on space vehicles. AESSIM is comprised of sun-pointed spectrometers and newly-developed, secondary standards of spectral irradiance for the EUV. Use of the in-orbit standard sources will eliminate the uncertainties caused by changes in spectrometer efficiency that have plagued all previous measurements of the solar spectral EUV flux.

  13. Online Deviation Detection for Medical Processes

    PubMed Central

    Christov, Stefan C.; Avrunin, George S.; Clarke, Lori A.

    2014-01-01

    Human errors are a major concern in many medical processes. To help address this problem, we are investigating an approach for automatically detecting when performers of a medical process deviate from the acceptable ways of performing that process as specified by a detailed process model. Such deviations could represent errors and, thus, detecting and reporting deviations as they occur could help catch errors before harm is done. In this paper, we identify important issues related to the feasibility of the proposed approach and empirically evaluate the approach for two medical procedures, chemotherapy and blood transfusion. For the evaluation, we use the process models to generate sample process executions that we then seed with synthetic errors. The process models describe the coordination of activities of different process performers in normal, as well as in exceptional situations. The evaluation results suggest that the proposed approach could be applied in clinical settings to help catch errors before harm is done. PMID:25954343

  14. [Fibrin glue for operative correction of septal deviations].

    PubMed

    Boenisch, M; Nolst Trenité, G J

    2004-11-01

    The routine procedure after correction of septal deviations is the utilization of endonasal packing in order to avoid septal haematoma. However, the mechanical pressure of this packing damages the mucociliar activity of the mucosa and causes lymphoedema by blocking the lymphatic vessels. Besides it represents a foreign body within the nose causing pain and unpleasant feeling for the patient. In order to avoid these disadvantages, in 57 patients we used fibrin glue instead of nasal packing. After correction of the septal deviation the two mucoperichondrium blades where fixed together with Tissucol Duo Quick. This technique not only leads to haemostasis, but also provides fixation of the newly modeled septum. In only one patient we found a small unilateral septal haematoma, in all other cases the postoperative period showed no complications. Patients had a significant reduction of endonasal crusts and postoperative swelling. Patients comfort increased significant without the (standard) nasal packing.

  15. The Fremantle Primary Prevention Study: a multicentre randomised trial of absolute cardiovascular risk reduction

    PubMed Central

    Brett, Tom; Arnold-Reed, Diane; Phan, Cam; Cadden, Frances; Walker, William; Manea-Walley, Wendy; Mora, Noelene; Young, Julie; Bulsara, Max

    2011-01-01

    Background Cardiovascular disease (CVD) is the leading cause of global mortality. Risk factor management in clinical practice often relies on relative risk modification rather than the more appropriate absolute risk assessment. Aim To determine whether patients receiving more-frequently designated GP visits had increased benefit in terms of their absolute CVD risk assessment, as compared with patients in receipt of their usual GP care. Design and setting Prospective, open, pragmatic block randomised study in a 1:1 group allocation ratio in three Western Australian general practices. Method A convenience sample (n = 1200) of patients aged 40–80 years were randomised to 3-monthly GP visits (five in total for the intensive) or usual GP care (two in total for the opportunistic), with 12 months’ follow-up. The main outcome was absolute CVD risk scores based on the New Zealand Cardiovascular Risk Calculator. Others outcome measures were weight, height, waist circumference, blood pressure, and fasting blood lipids and glucose. Results There were 600 patients per group at baseline. At 12 months’ analysis there were 543 in the intensive group and 569 in the opportunistic group. Mean (standard deviation [SD]) absolute CVD risk reduced significantly between baseline and 12 months in the intensive group (6.28% [5.11] to 6.10% [4.94]) but not in the opportunistic group (6.27% [5.10] to 6.24% [5.38]). There was a significant reduction between baseline and 12 months in mean (SD) total cholesterol (5.28 mmol/l [0.94] to 5.08 mmol/l [0.96]); low-density lipoprotein cholesterol (3.08 mmol/l [0.87] to 2.95 mmol/l [0.89]); triglyceride (1.45 mmol/l [0.86] to 1.36 mmol/l [0.84]); and in mean (SD) waist circumference in men (98.74 cm [10.70] to 97.13 cm [10.20]) and females (90.64 cm [14.62] to 88.96 cm [14.00]) in the intensive group. Conclusion A targeted approach using absolute risk calculators can be used in primary care to modify global CVD risk assessment. PMID:22520669

  16. The Absolute Spectrum Polarimeter (ASP)

    NASA Technical Reports Server (NTRS)

    Kogut, A. J.

    2010-01-01

    The Absolute Spectrum Polarimeter (ASP) is an Explorer-class mission to map the absolute intensity and linear polarization of the cosmic microwave background and diffuse astrophysical foregrounds over the full sky from 30 GHz to 5 THz. The principal science goal is the detection and characterization of linear polarization from an inflationary epoch in the early universe, with tensor-to-scalar ratio r much greater than 1O(raised to the power of { -3}) and Compton distortion y < 10 (raised to the power of{-6}). We describe the ASP instrument and mission architecture needed to detect the signature of an inflationary epoch in the early universe using only 4 semiconductor bolometers.

  17. Physics of negative absolute temperatures

    NASA Astrophysics Data System (ADS)

    Abraham, Eitan; Penrose, Oliver

    2017-01-01

    Negative absolute temperatures were introduced into experimental physics by Purcell and Pound, who successfully applied this concept to nuclear spins; nevertheless, the concept has proved controversial: a recent article aroused considerable interest by its claim, based on a classical entropy formula (the "volume entropy") due to Gibbs, that negative temperatures violated basic principles of statistical thermodynamics. Here we give a thermodynamic analysis that confirms the negative-temperature interpretation of the Purcell-Pound experiments. We also examine the principal arguments that have been advanced against the negative temperature concept; we find that these arguments are not logically compelling, and moreover that the underlying "volume" entropy formula leads to predictions inconsistent with existing experimental results on nuclear spins. We conclude that, despite the counterarguments, negative absolute temperatures make good theoretical sense and did occur in the experiments designed to produce them.

  18. Optomechanics for absolute rotation detection

    NASA Astrophysics Data System (ADS)

    Davuluri, Sankar

    2016-07-01

    In this article, we present an application of optomechanical cavity for the absolute rotation detection. The optomechanical cavity is arranged in a Michelson interferometer in such a way that the classical centrifugal force due to rotation changes the length of the optomechanical cavity. The change in the cavity length induces a shift in the frequency of the cavity mode. The phase shift corresponding to the frequency shift in the cavity mode is measured at the interferometer output to estimate the angular velocity of absolute rotation. We derived an analytic expression to estimate the minimum detectable rotation rate in our scheme for a given optomechanical cavity. Temperature dependence of the rotation detection sensitivity is studied.

  19. 41 CFR 109-1.5304 - Deviations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... High Risk Personal Property § 109-1.5304 Deviations. (a) Life cycle control determinations. When the HFO approves a contractor program containing controls, other than life cycle control consistent with... Secretary for Procurement and Assistance Management. A HFO's decision not to provide life-cycle...

  20. 41 CFR 109-1.5304 - Deviations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... High Risk Personal Property § 109-1.5304 Deviations. (a) Life cycle control determinations. When the HFO approves a contractor program containing controls, other than life cycle control consistent with... Secretary for Procurement and Assistance Management. A HFO's decision not to provide life-cycle...

  1. 2 CFR 170.115 - Deviations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 2 Grants and Agreements 1 2013-01-01 2013-01-01 false Deviations. 170.115 Section 170.115 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET GOVERNMENTWIDE GUIDANCE FOR GRANTS AND AGREEMENTS NATIONAL POLICY REQUIREMENTS...

  2. 2 CFR 170.115 - Deviations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Deviations. 170.115 Section 170.115 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET GOVERNMENTWIDE GUIDANCE FOR GRANTS AND AGREEMENTS Reserved REPORTING SUBAWARD AND...

  3. 2 CFR 25.115 - Deviations.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 2 Grants and Agreements 1 2014-01-01 2014-01-01 false Deviations. 25.115 Section 25.115 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET GOVERNMENTWIDE GUIDANCE FOR GRANTS AND AGREEMENTS Reserved UNIVERSAL IDENTIFIER AND CENTRAL...

  4. 2 CFR 25.115 - Deviations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 2 Grants and Agreements 1 2013-01-01 2013-01-01 false Deviations. 25.115 Section 25.115 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET GOVERNMENTWIDE GUIDANCE FOR GRANTS AND AGREEMENTS PRE-AWARD RESPONSIBILITIES UNIVERSAL IDENTIFIER AND...

  5. 2 CFR 25.115 - Deviations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 2 Grants and Agreements 1 2012-01-01 2012-01-01 false Deviations. 25.115 Section 25.115 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET GOVERNMENTWIDE GUIDANCE FOR GRANTS AND AGREEMENTS PRE-AWARD RESPONSIBILITIES UNIVERSAL IDENTIFIER AND...

  6. 2 CFR 170.115 - Deviations.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 2 Grants and Agreements 1 2012-01-01 2012-01-01 false Deviations. 170.115 Section 170.115 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET GOVERNMENTWIDE GUIDANCE FOR GRANTS AND AGREEMENTS NATIONAL POLICY REQUIREMENTS...

  7. Manifestations of Deviation in the Adolescent Subculture

    ERIC Educational Resources Information Center

    Sobkin, V. S.; Abrosimova, Z. B.; Adamchuk, D. V.; Baranova, E. V.

    2005-01-01

    In this article the authors look at questions relating to school students' attitudes toward types of deviation such as smoking and the use of alcohol and narcotics. The empirical material is divided into the following topics: how widespread these forms of behavior are; motives that cause adolescents to start smoking, using alcohol, and taking…

  8. 2 CFR 25.115 - Deviations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Deviations. 25.115 Section 25.115 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET GOVERNMENTWIDE GUIDANCE FOR GRANTS AND AGREEMENTS Pre-award responsibilities UNIVERSAL IDENTIFIER AND...

  9. 2 CFR 170.115 - Deviations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Deviations. 170.115 Section 170.115 Grants and Agreements Office of Management and Budget Guidance for Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET GOVERNMENTWIDE GUIDANCE FOR GRANTS AND AGREEMENTS REPORTING SUBAWARD AND...

  10. 15 CFR 14.4 - Deviations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... ORGANIZATIONS General § 14.4 Deviations. The Office of Management and Budget (OMB) may grant exceptions for.... Exceptions on a case-by-case basis may also be made by the Assistant Secretary. An exception made on a case-by-case basis will apply to a single award....

  11. 22 CFR 226.4 - Deviations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... ORGANIZATIONS General § 226.4 Deviations. The Office of Management and Budget (OMB) may grant exceptions for... awarding small awards, except for those requirements which are statutory. Exceptions on a case-by-case basis may also be made by the USAID Deputy Assistant Administrator for Management....

  12. 49 CFR 19.4 - Deviations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 1 2013-10-01 2013-10-01 false Deviations. 19.4 Section 19.4 Transportation Office of the Secretary of Transportation UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS General §...

  13. 49 CFR 19.4 - Deviations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 49 Transportation 1 2012-10-01 2012-10-01 false Deviations. 19.4 Section 19.4 Transportation Office of the Secretary of Transportation UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS General §...

  14. 48 CFR 1480.403 - Deviations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... officials may authorize a deviation for an IA acquisition: For a proposed contract action . . . The... the IA Procurement Chief, absent a CCO). Exceeding $550,000 but not exceeding $11.5 million IA... solicitation when IA makes the following determinations and the appropriate official takes the...

  15. 7 CFR 2502.3 - Deviations.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 15 2013-01-01 2013-01-01 false Deviations. 2502.3 Section 2502.3 Agriculture Regulations of the Department of Agriculture (Continued) OFFICE OF ADVOCACY AND OUTREACH, DEPARTMENT OF AGRICULTURE AGRICULTURAL CAREER AND EMPLOYMENT (ACE) GRANTS PROGRAM General Information § 2502.3...

  16. 40 CFR 30.4 - Deviations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Deviations. 30.4 Section 30.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND...

  17. 40 CFR 30.4 - Deviations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Deviations. 30.4 Section 30.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND...

  18. 40 CFR 30.4 - Deviations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Deviations. 30.4 Section 30.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND...

  19. 40 CFR 30.4 - Deviations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Deviations. 30.4 Section 30.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND...

  20. 40 CFR 30.4 - Deviations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Deviations. 30.4 Section 30.4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND...

  1. Bodily Deviations and Body Image in Adolescence

    ERIC Educational Resources Information Center

    Vilhjalmsson, Runar; Kristjansdottir, Gudrun; Ward, Dianne S.

    2012-01-01

    Adolescents with unusually sized or shaped bodies may experience ridicule, rejection, or exclusion based on their negatively valued bodily characteristics. Such experiences can have negative consequences for a person's image and evaluation of self. This study focuses on the relationship between bodily deviations and body image and is based on a…

  2. New low-cost dimensionally stable composite linear absolute position encoder scale

    NASA Astrophysics Data System (ADS)

    Hassler, William L., Jr.; Nakayama, Robert K.

    1990-11-01

    A major problem in the use of standard linear position encoders is that the etched glass scales they use have a coefficient of thermal expansion (C. T. E. ) of about 1 1 . Oppm/ C. This means that their position measurements drift with changes in environmental temperature proportional to their C. T. E. . A new low cost dimensionally stable composite scale was made for use in a new absolute linear position encoder. The unidirectional Polyphenylene Sulfide/AS4 carbon fiber composite material that this scale is made of was tested for dimensional stability with respect to changes in temperature humidity and creep. The C. T. E. of the scale material was measured to be nominally 0. 29 ppm/ C with a standard deviation of 0. 12 over the operating temperature range of -2 to 62 C. The overall displacement strain due to 98 moisture absorption relative to 0 moisture absorption was measured to be 9 ppm. The strain due to stress-relief creep was found to be a maximum of 3 ppm over a period of 173 days. These results show that a linear position encoder scale made of this material is superior to those made of the standard glass currently being used and more cost effective than fused silica for most applications. 1.

  3. Clock time is absolute and universal

    NASA Astrophysics Data System (ADS)

    Shen, Xinhang

    2015-09-01

    A critical error is found in the Special Theory of Relativity (STR): mixing up the concepts of the STR abstract time of a reference frame and the displayed time of a physical clock, which leads to use the properties of the abstract time to predict time dilation on physical clocks and all other physical processes. Actually, a clock can never directly measure the abstract time, but can only record the result of a physical process during a period of the abstract time such as the number of cycles of oscillation which is the multiplication of the abstract time and the frequency of oscillation. After Lorentz Transformation, the abstract time of a reference frame expands by a factor gamma, but the frequency of a clock decreases by the same factor gamma, and the resulting multiplication i.e. the displayed time of a moving clock remains unchanged. That is, the displayed time of any physical clock is an invariant of Lorentz Transformation. The Lorentz invariance of the displayed times of clocks can further prove within the framework of STR our earth based standard physical time is absolute, universal and independent of inertial reference frames as confirmed by both the physical fact of the universal synchronization of clocks on the GPS satellites and clocks on the earth, and the theoretical existence of the absolute and universal Galilean time in STR which has proved that time dilation and space contraction are pure illusions of STR. The existence of the absolute and universal time in STR has directly denied that the reference frame dependent abstract time of STR is the physical time, and therefore, STR is wrong and all its predictions can never happen in the physical world.

  4. Absolute Radiometric Calibration of EUNIS-06

    NASA Technical Reports Server (NTRS)

    Thomas, R. J.; Rabin, D. M.; Kent, B. J.; Paustian, W.

    2007-01-01

    The Extreme-Ultraviolet Normal-Incidence Spectrometer (EUNIS) is a soundingrocket payload that obtains imaged high-resolution spectra of individual solar features, providing information about the Sun's corona and upper transition region. Shortly after its successful initial flight last year, a complete end-to-end calibration was carried out to determine the instrument's absolute radiometric response over its Longwave bandpass of 300 - 370A. The measurements were done at the Rutherford-Appleton Laboratory (RAL) in England, using the same vacuum facility and EUV radiation source used in the pre-flight calibrations of both SOHO/CDS and Hinode/EIS, as well as in three post-flight calibrations of our SERTS sounding rocket payload, the precursor to EUNIS. The unique radiation source provided by the Physikalisch-Technische Bundesanstalt (PTB) had been calibrated to an absolute accuracy of 7% (l-sigma) at 12 wavelengths covering our bandpass directly against the Berlin electron storage ring BESSY, which is itself a primary radiometric source standard. Scans of the EUNIS aperture were made to determine the instrument's absolute spectral sensitivity to +- 25%, considering all sources of error, and demonstrate that EUNIS-06 was the most sensitive solar E W spectrometer yet flown. The results will be matched against prior calibrations which relied on combining measurements of individual optical components, and on comparisons with theoretically predicted 'insensitive' line ratios. Coordinated observations were made during the EUNIS-06 flight by SOHO/CDS and EIT that will allow re-calibrations of those instruments as well. In addition, future EUNIS flights will provide similar calibration updates for TRACE, Hinode/EIS, and STEREO/SECCHI/EUVI.

  5. Absolute Quantification of Rifampicin by MALDI Imaging Mass Spectrometry Using Multiple TOF/TOF Events in a Single Laser Shot.

    PubMed

    Prentice, Boone M; Chumbley, Chad W; Caprioli, Richard M

    2017-01-01

    Matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) allows for the visualization of molecular distributions within tissue sections. While providing excellent molecular specificity and spatial information, absolute quantification by MALDI IMS remains challenging. Especially in the low molecular weight region of the spectrum, analysis is complicated by matrix interferences and ionization suppression. Though tandem mass spectrometry (MS/MS) can be used to ensure chemical specificity and improve sensitivity by eliminating chemical noise, typical MALDI MS/MS modalities only scan for a single MS/MS event per laser shot. Herein, we describe TOF/TOF instrumentation that enables multiple fragmentation events to be performed in a single laser shot, allowing the intensity of the analyte to be referenced to the intensity of the internal standard in each laser shot while maintaining the benefits of MS/MS. This approach is illustrated by the quantitative analyses of rifampicin (RIF), an antibiotic used to treat tuberculosis, in pooled human plasma using rifapentine (RPT) as an internal standard. The results show greater than 4-fold improvements in relative standard deviation as well as improved coefficients of determination (R(2)) and accuracy (>93% quality controls, <9% relative errors). This technology is used as an imaging modality to measure absolute RIF concentrations in liver tissue from an animal dosed in vivo. Each microspot in the quantitative image measures the local RIF concentration in the tissue section, providing absolute pixel-to-pixel quantification from different tissue microenvironments. The average concentration determined by IMS is in agreement with the concentration determined by HPLC-MS/MS, showing a percent difference of 10.6%. Graphical Abstract ᅟ.

  6. Absolute Quantification of Rifampicin by MALDI Imaging Mass Spectrometry Using Multiple TOF/TOF Events in a Single Laser Shot

    NASA Astrophysics Data System (ADS)

    Prentice, Boone M.; Chumbley, Chad W.; Caprioli, Richard M.

    2017-01-01

    Matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) allows for the visualization of molecular distributions within tissue sections. While providing excellent molecular specificity and spatial information, absolute quantification by MALDI IMS remains challenging. Especially in the low molecular weight region of the spectrum, analysis is complicated by matrix interferences and ionization suppression. Though tandem mass spectrometry (MS/MS) can be used to ensure chemical specificity and improve sensitivity by eliminating chemical noise, typical MALDI MS/MS modalities only scan for a single MS/MS event per laser shot. Herein, we describe TOF/TOF instrumentation that enables multiple fragmentation events to be performed in a single laser shot, allowing the intensity of the analyte to be referenced to the intensity of the internal standard in each laser shot while maintaining the benefits of MS/MS. This approach is illustrated by the quantitative analyses of rifampicin (RIF), an antibiotic used to treat tuberculosis, in pooled human plasma using rifapentine (RPT) as an internal standard. The results show greater than 4-fold improvements in relative standard deviation as well as improved coefficients of determination (R2) and accuracy (>93% quality controls, <9% relative errors). This technology is used as an imaging modality to measure absolute RIF concentrations in liver tissue from an animal dosed in vivo. Each microspot in the quantitative image measures the local RIF concentration in the tissue section, providing absolute pixel-to-pixel quantification from different tissue microenvironments. The average concentration determined by IMS is in agreement with the concentration determined by HPLC-MS/MS, showing a percent difference of 10.6%.

  7. Deviations from LTE in a stellar atmosphere

    NASA Technical Reports Server (NTRS)

    Kalkofen, W.; Klein, R. I.; Stein, R. F.

    1979-01-01

    Deviations for LTE are investigated in an atmosphere of hydrogen atoms with one bound level, satisfying the equations of radiative, hydrostatic, and statistical equilibrium. The departure coefficient and the kinetic temperature as functions of the frequency dependence of the radiative cross section are studied analytically and numerically. Near the outer boundary of the atmosphere, the departure coefficient is smaller than unity when the radiative cross section grows with frequency faster than with the square of frequency; it exceeds unity otherwise. Far from the boundary the departure coefficient tends to exceed unity for any frequency dependence of the radiative cross section. Overpopulation always implies that the kinetic temperature in the statistical-equilibrium atmosphere is higher than the temperature in the corresponding LTE atmosphere. Upper and lower bounds on the kinetic temperature are given for an atmosphere with deviations from LTE only in the optically shallow layers when the emergent intensity can be described by a radiation temperature.

  8. On large deviations for ensembles of distributions

    SciTech Connect

    Khrychev, D A

    2013-11-30

    The paper is concerned with the large deviations problem in the Freidlin-Wentzell formulation without the assumption of the uniqueness of the solution to the equation involving white noise. In other words, it is assumed that for each ε>0 the nonempty set P{sub ε} of weak solutions is not necessarily a singleton. Analogues of a number of concepts in the theory of large deviations are introduced for the set (P{sub ε}, ε>0), hereafter referred to as an ensemble of distributions. The ensembles of weak solutions of an n-dimensional stochastic Navier-Stokes system and stochastic wave equation with power-law nonlinearity are shown to be uniformly exponentially tight. An idempotent Wiener process in a Hilbert space and idempotent partial differential equations are defined. The accumulation points in the sense of large deviations of the ensembles in question are shown to be weak solutions of the corresponding idempotent equations. Bibliography: 14 titles.

  9. Absolute calibration of optical tweezers

    SciTech Connect

    Viana, N.B.; Mazolli, A.; Maia Neto, P.A.; Nussenzveig, H.M.; Rocha, M.S.; Mesquita, O.N.

    2006-03-27

    As a step toward absolute calibration of optical tweezers, a first-principles theory of trapping forces with no adjustable parameters, corrected for spherical aberration, is experimentally tested. Employing two very different setups, we find generally very good agreement for the transverse trap stiffness as a function of microsphere radius for a broad range of radii, including the values employed in practice, and at different sample chamber depths. The domain of validity of the WKB ('geometrical optics') approximation to the theory is verified. Theoretical predictions for the trapping threshold, peak position, depth variation, multiple equilibria, and 'jump' effects are also confirmed.

  10. Method based on chirp decomposition for dispersion mismatch compensation in precision absolute distance measurement using swept-wavelength interferometry.

    PubMed

    Lu, Cheng; Liu, Guodong; Liu, Bingguo; Chen, Fengdong; Hu, Tao; Zhuang, Zhitao; Xu, Xinke; Gan, Yu

    2015-12-14

    We establish a theoretical model of dispersion mismatch in absolute distance measurements using swept-wavelength interferometry (SWI) and propose a novel dispersion mismatch compensation method called chirp decomposition. This method separates the dispersion coefficient and distance under test, which ensures dispersion mismatch compensation without introducing additional random errors. In the measurement of a target located at 3.9 m, a measurement resolution of 45.9 μm is obtained, which is close to the theoretical resolution, and a standard deviation of 0.74 μm is obtained, which is better than the traditional method. The measurement results are compared to a single-frequency laser interferometer. The target moves from 1 m to 3.7 m, and the measurement precision using the new method is less than 0.81 μm.

  11. From Hubble's Next Generation Spectral Library (NGSL) to Absolute Fluxes

    NASA Astrophysics Data System (ADS)

    Heap, S. R.; Lindler, D.

    2016-05-01

    Hubble's Next Generation Spectral Library (NGSL) consists of R˜1000 spectra of 374 stars of assorted temperature, gravity, and metallicity. Each spectrum covers the wavelength range, 0.18-1.03 μ. The library can be viewed and/or downloaded from the website, http://archive.stsci.edu/prepds/stisngsl/. Stars in the NGSL are now being used as absolute flux standards at ground-based observatories. However, the uncertainty in the absolute flux is about 2%, which does not meet the requirements of dark-energy surveys. We have therefore developed an observing procedure, data-reduction procedure, and correction algorithms that should yield fluxes with uncertainties less than 1%.

  12. Absolute gain measurement by the image method under mismatched condition

    NASA Technical Reports Server (NTRS)

    Lee, Richard Q.; Baddour, Maurice F.

    1987-01-01

    Purcell's image method for measuring the absolute gain of an antenna is particularly attractive for small test antennas. The method is simple to use and utilizes only one antenna with a reflecting plane to provide an image for the receiving antenna. However, the method provides accurate results only if the antenna is matched to its waveguide. In this paper, a waveguide junction analysis is developed to determine the gain of an antenna under mismatched condition. Absolute gain measurements for two standard gain horn antennas have been carried out. Experimental results agree closely with published data.

  13. Measuring and Plotting Surface-Contour Deviations

    NASA Technical Reports Server (NTRS)

    Aragon, Lino A.; Shuck, Thomas; Crockett, Leroy K.

    1987-01-01

    Hand-held device measures deviation of contour of surface from desired contour and provides output to x-y plotter. Carriage on device rolled along track representing desired contour, while spring-loaded stylus on device deflects perpendicularly to track to follow surface. Operator moves carriage of contour-measuring device on beamlike track. Stylus on carriage traces contour of surface above it. Carriage of measuring device holds transducer measuring cross-track displacement of surface from desired contour, and multiple-turn potentiometer measuring position along track.

  14. Meiosis and its deviations in polyploid plants.

    PubMed

    Grandont, L; Jenczewski, E; Lloyd, A

    2013-01-01

    Meiosis is a fundamental process in all sexual organisms that ensures fertility and genome stability and creates genetic diversity. For each of these outcomes, the exclusive formation of crossovers between homologous chromosomes is needed. This is more difficult to achieve in polyploid species which have more than 2 sets of chromosomes able to recombine. In this review, we describe how meiosis and meiotic recombination 'deviate' in polyploid plants compared to diploids, and give an overview of current knowledge on how they are regulated. See also the sister article focusing on animals by Stenberg and Saura in this themed issue.

  15. Penile ossification and acquired penile deviation.

    PubMed

    Vahlensieck, W K; Schaefer, H E; Westenfelder, M

    1995-01-01

    We report on 3 patients with penile deviation during erection caused by ossification in the corpora cavernosa. In each case hard plaques could be palpated. These indurations were removed through a dorsal longitudinal incision. Histologically, solid bone was demonstrable. Two patients were able to resume normal sexual intercourse, but one became impotent following postoperative cavernitis. Penile ossification is rare in man, and its etiology is unknown. It bears no relationship to the os penis normally present in many other mammals. Diagnosis is best made by palpation and X-ray examination. The treatment of choice for symptomatic ossification is surgical excision.

  16. Perception via the Deviated Eye in Strabismus

    PubMed Central

    Economides, John R.; Adams, Daniel L.; Horton, Jonathan C.

    2012-01-01

    Misalignment of the eyes can lead to double vision and visual confusion. However, these sensations are rare when strabismus is acquired early in life, because the extra image is suppressed. To explore the mechanism of perceptual suppression in strabismus, the visual fields were mapped binocularly in 14 human subjects with exotropia. Subjects wore red/blue filter glasses to permit dichoptic stimulation while fixating a central target on a tangent screen. A purple stimulus was flashed at a peripheral location; its reported color (“red” or “blue”) revealed which eye’s image was perceived at that locus. The maps showed a vertical border between the center of gaze for each eye, splitting the visual field into two separate regions. In each region, perception was mediated by only one eye, with suppression of the other eye. Unexpectedly, stimuli falling on the fovea of the deviated eye were seen in all subjects. However, they were perceived in a location shifted by the angle of ocular deviation. This plasticity in the coding of visual direction allows accurate localization of objects everywhere in the visual scene, despite the presence of strabismus. PMID:22836262

  17. An absolute dose determination of helical tomotherapy accelerator, TomoTherapy High-Art II

    SciTech Connect

    Bailat, Claude J.; Buchillier, Thierry; Pachoud, Marc; Moeckli, Raphaeel; Bochud, Francois O.

    2009-09-15

    practice and therefore measured the dose using a Farmer-type instrument (model NE 2571) as well. Results: We found the tomotherapy TPR{sub 20,10} value to be around 0.629, which is close to a 4 MV conventional linear accelerator value. During static irradiation, the secondary standard and the alanine dosimeters were compatible within 0.5%. The A1SL relative deviation to the secondary standard was 1.2% and the NE2571 relative deviation to the secondary standard was -1.7%. The measurement in dynamic helical mode found the different dosimeters compatible within 1.4% and the alanine dosimeters and the secondary standard were even found under 0.2%. Conclusions: We found that the different methods are all within uncertainties as well as globally coherent, and the specific limitations of the various dosimeters are discussed in order to help the medical physicist design an independent reference system. We demonstrated that, taking into account the particular reference conditions, one can use an ionization chamber calibrated for conventional linear accelerators to assert the absolute dose delivered by a tomotherapy accelerator.

  18. The impact of water temperature on the measurement of absolute dose

    NASA Astrophysics Data System (ADS)

    Islam, Naveed Mehdi

    To standardize reference dosimetry in radiation therapy, Task Group 51 (TG 51) of American Association of Physicist's in Medicine (AAPM) recommends that dose calibration measurements be made in a water tank at a depth of 10 cm and at a reference geometry. Methodologies are provided for calculating various correction factors to be applied in calculating the absolute dose. However the protocol does not specify the water temperature to be used. In practice, the temperature of water during dosimetry may vary considerably between independent sessions and different centers. In this work the effect of water temperature on absolute dosimetry has been investigated. Density of water varies with temperature, which in turn may impact the beam attenuation and scatter properties. Furthermore, due to thermal expansion or contraction air volume inside the chamber may change. All of these effects can result in a change in the measurement. Dosimetric measurements were made using a Farmer type ion chamber on a Varian Linear Accelerator for 6 MV and 23 MV photon energies for temperatures ranging from 10 to 40 °C. A thermal insulation was designed for the water tank in order to maintain relatively stable temperature over the duration of the experiment. Dose measured at higher temperatures were found to be consistently higher by a very small magnitude. Although the differences in dose were less than the uncertainty in each measurement, a linear regression of the data suggests that the trend is statistically significant with p-values of 0.002 and 0.013 for 6 and 23 MV beams respectively. For a 10 degree difference in water phantom temperatures, which is a realistic deviation across clinics, the final calculated reference dose can differ by 0.24% or more. To address this effect, first a reference temperature (e.g.22 °C) can be set as the standard; subsequently a correction factor can be implemented for deviations from this reference. Such a correction factor is expected to be of similar

  19. Absolute irradiance of the Moon for on-orbit calibration

    USGS Publications Warehouse

    Stone, T.C.; Kieffer, H.H.; ,

    2002-01-01

    The recognized need for on-orbit calibration of remote sensing imaging instruments drives the ROLO project effort to characterize the Moon for use as an absolute radiance source. For over 5 years the ground-based ROLO telescopes have acquired spatially-resolved lunar images in 23 VNIR (Moon diameter ???500 pixels) and 9 SWIR (???250 pixels) passbands at phase angles within ??90 degrees. A numerical model for lunar irradiance has been developed which fits hundreds of ROLO images in each band, corrected for atmospheric extinction and calibrated to absolute radiance, then integrated to irradiance. The band-coupled extinction algorithm uses absorption spectra of several gases and aerosols derived from MODTRAN to fit time-dependent component abundances to nightly observations of standard stars. The absolute radiance scale is based upon independent telescopic measurements of the star Vega. The fitting process yields uncertainties in lunar relative irradiance over small ranges of phase angle and the full range of lunar libration well under 0.5%. A larger source of uncertainty enters in the absolute solar spectral irradiance, especially in the SWIR, where solar models disagree by up to 6%. Results of ROLO model direct comparisons to spacecraft observations demonstrate the ability of the technique to track sensor responsivity drifts to sub-percent precision. Intercomparisons among instruments provide key insights into both calibration issues and the absolute scale for lunar irradiance.

  20. Spotting deviations from R2 inflation

    NASA Astrophysics Data System (ADS)

    de la Cruz-Dombriz, Álvaro; Elizalde, Emilio; Odintsov, Sergei D.; Sáez-Gómez, Diego

    2016-05-01

    We discuss the soundness of inflationary scenarios in theories beyond the Starobinsky model, namely a class of theories described by arbitrary functions of the Ricci scalar and the K-essence field. We discuss the pathologies associated with higher-order equations of motion which will be shown to constrain the stability of this class of theories. We provide a general framework to calculate the slow-roll parameters and the corresponding mappings to the theory parameters. For paradigmatic gravitational models within the class of theories under consideration we illustrate the power of the Planck/Bicep2 latest results to constrain such gravitational Lagrangians. Finally, bounds for potential deviations from Starobinsky-like inflation are derived.

  1. Aircraft noise-induced awakenings are more reasonably predicted from relative than from absolute sound exposure levels.

    PubMed

    Fidell, Sanford; Tabachnick, Barbara; Mestre, Vincent; Fidell, Linda

    2013-11-01

    Assessment of aircraft noise-induced sleep disturbance is problematic for several reasons. Current assessment methods are based on sparse evidence and limited understandings; predictions of awakening prevalence rates based on indoor absolute sound exposure levels (SELs) fail to account for appreciable amounts of variance in dosage-response relationships and are not freely generalizable from airport to airport; and predicted awakening rates do not differ significantly from zero over a wide range of SELs. Even in conjunction with additional predictors, such as time of night and assumed individual differences in "sensitivity to awakening," nominally SEL-based predictions of awakening rates remain of limited utility and are easily misapplied and misinterpreted. Probabilities of awakening are more closely related to SELs scaled in units of standard deviates of local distributions of aircraft SELs, than to absolute sound levels. Self-selection of residential populations for tolerance of nighttime noise and habituation to airport noise environments offer more parsimonious and useful explanations for differences in awakening rates at disparate airports than assumed individual differences in sensitivity to awakening.

  2. MSTAR: an absolute metrology sensor with sub-micron accuracy for space-based applications

    NASA Technical Reports Server (NTRS)

    Peters, Robert D.; Lay, Oliver P.; Dubovitsky, Serge; Burger, Johan P.; Jeganathan, Muthu

    2004-01-01

    The MSTAR sensor is a new system for measuring absolute distance, capable of resolving the integer cycle ambiguity of standard interferometers, and making it possible to measure distance with subnanometer accuracy.

  3. Quantum Cloning for Absolute Radiometry

    SciTech Connect

    Sanguinetti, Bruno; Pomarico, Enrico; Sekatski, Pavel; Zbinden, Hugo; Gisin, Nicolas

    2010-08-20

    In the quantum regime information can be copied with only a finite fidelity. This fidelity gradually increases to 1 as the system becomes classical. In this Letter we show how this fact can be used to directly measure the amount of radiated power. We demonstrate how these principles can be used to build a practical primary standard.

  4. Large deviations for nonlocal stochastic neural fields.

    PubMed

    Kuehn, Christian; Riedler, Martin G

    2014-04-17

    We study the effect of additive noise on integro-differential neural field equations. In particular, we analyze an Amari-type model driven by a Q-Wiener process, and focus on noise-induced transitions and escape. We argue that proving a sharp Kramers' law for neural fields poses substantial difficulties, but that one may transfer techniques from stochastic partial differential equations to establish a large deviation principle (LDP). Then we demonstrate that an efficient finite-dimensional approximation of the stochastic neural field equation can be achieved using a Galerkin method and that the resulting finite-dimensional rate function for the LDP can have a multiscale structure in certain cases. These results form the starting point for an efficient practical computation of the LDP. Our approach also provides the technical basis for further rigorous study of noise-induced transitions in neural fields based on Galerkin approximations.Mathematics Subject Classification (2000): 60F10, 60H15, 65M60, 92C20.

  5. Program helps quickly calculate deviated well path

    SciTech Connect

    Gardner, M.P. )

    1993-11-22

    A BASIC computer program quickly calculates the angle and measured depth of a simple directional well given only the true vertical depth and total displacement of the target. Many petroleum engineers and geologists need a quick, easy method to calculate the angle and measured depth necessary to reach a target in a proposed deviated well bore. Too many of the existing programs are large and require much input data. The drilling literature is full of equations and methods to calculate the course of well paths from surveys taken after a well is drilled. Very little information, however, covers how to calculate well bore trajectories for proposed wells from limited data. Furthermore, many of the equations are quite complex and difficult to use. A figure lists a computer program with the equations to calculate the well bore trajectory necessary to reach a given displacement and true vertical depth (TVD) for a simple build plant. It can be run on an IBM compatible computer with MS-DOS version 5 or higher, QBasic, or any BASIC that does no require line numbers. QBasic 4.5 compiler will also run the program. The equations are based on conventional geometry and trigonometry.

  6. Meiosis and its deviations in polyploid animals.

    PubMed

    Stenberg, P; Saura, A

    2013-01-01

    We review the different modes of meiosis and its deviations encountered in polyploid animals. Bisexual reproduction involving normal meiosis occurs in some allopolyploid frogs with variable degrees of polyploidy. Aberrant modes of bisexual reproduction include gynogenesis, where a sperm stimulates the egg to develop. The sperm may enter the egg but there is no fertilization and syngamy. In hybridogenesis, a genome is eliminated to produce haploid or diploid eggs or sperm. Ploidy can be elevated by fertilization with a haploid sperm in meiotic hybridogenesis, which elevates the ploidy of hybrid offspring such that they produce diploid gametes. Polyploids are then produced in the next generation. In kleptogenesis, females acquire full or partial genomes from their partners. In pre-equalizing hybrid meiosis, one genome is transmitted in the Mendelian fashion, while the other is transmitted clonally. Parthenogenetic animals have a very wide range of mechanisms for restoring or maintaining the mother's ploidy level, including gamete duplication, terminal fusion, central fusion, fusion of the first polar nucleus with the product of the first division, and premeiotic duplication followed by a normal meiosis. In apomictic parthenogenesis, meiosis is replaced by what is effectively mitotic cell division. The above modes have different evolutionary consequences, which are discussed. See also the sister article by Grandont et al. in this themed issue.

  7. Large Deviations for Nonlocal Stochastic Neural Fields

    PubMed Central

    2014-01-01

    We study the effect of additive noise on integro-differential neural field equations. In particular, we analyze an Amari-type model driven by a Q-Wiener process, and focus on noise-induced transitions and escape. We argue that proving a sharp Kramers’ law for neural fields poses substantial difficulties, but that one may transfer techniques from stochastic partial differential equations to establish a large deviation principle (LDP). Then we demonstrate that an efficient finite-dimensional approximation of the stochastic neural field equation can be achieved using a Galerkin method and that the resulting finite-dimensional rate function for the LDP can have a multiscale structure in certain cases. These results form the starting point for an efficient practical computation of the LDP. Our approach also provides the technical basis for further rigorous study of noise-induced transitions in neural fields based on Galerkin approximations. Mathematics Subject Classification (2000): 60F10, 60H15, 65M60, 92C20. PMID:24742297

  8. Absolute Gravity Datum in the Age of Cold Atom Gravimeters

    NASA Astrophysics Data System (ADS)

    Childers, V. A.; Eckl, M. C.

    2014-12-01

    The international gravity datum is defined today by the International Gravity Standardization Net of 1971 (IGSN-71). The data supporting this network was measured in the 1950s and 60s using pendulum and spring-based gravimeter ties (plus some new ballistic absolute meters) to replace the prior protocol of referencing all gravity values to the earlier Potsdam value. Since this time, gravimeter technology has advanced significantly with the development and refinement of the FG-5 (the current standard of the industry) and again with the soon-to-be-available cold atom interferometric absolute gravimeters. This latest development is anticipated to provide improvement in the range of two orders of magnitude as compared to the measurement accuracy of technology utilized to develop ISGN-71. In this presentation, we will explore how the IGSN-71 might best be "modernized" given today's requirements and available instruments and resources. The National Geodetic Survey (NGS), along with other relevant US Government agencies, is concerned about establishing gravity control to establish and maintain high order geodetic networks as part of the nation's essential infrastructure. The need to modernize the nation's geodetic infrastructure was highlighted in "Precise Geodetic Infrastructure, National Requirements for a Shared Resource" National Academy of Science, 2010. The NGS mission, as dictated by Congress, is to establish and maintain the National Spatial Reference System, which includes gravity measurements. Absolute gravimeters measure the total gravity field directly and do not involve ties to other measurements. Periodic "intercomparisons" of multiple absolute gravimeters at reference gravity sites are used to constrain the behavior of the instruments to ensure that each would yield reasonably similar measurements of the same location (i.e. yield a sufficiently consistent datum when measured in disparate locales). New atomic interferometric gravimeters promise a significant

  9. Precision and accuracy in the quantitative analysis of biological samples by accelerator mass spectrometry: application in microdose absolute bioavailability studies.

    PubMed

    Gao, Lan; Li, Jing; Kasserra, Claudia; Song, Qi; Arjomand, Ali; Hesk, David; Chowdhury, Swapan K

    2011-07-15

    Determination of the pharmacokinetics and absolute bioavailability of an experimental compound, SCH 900518, following a 89.7 nCi (100 μg) intravenous (iv) dose of (14)C-SCH 900518 2 h post 200 mg oral administration of nonradiolabeled SCH 900518 to six healthy male subjects has been described. The plasma concentration of SCH 900518 was measured using a validated LC-MS/MS system, and accelerator mass spectrometry (AMS) was used for quantitative plasma (14)C-SCH 900518 concentration determination. Calibration standards and quality controls were included for every batch of sample analysis by AMS to ensure acceptable quality of the assay. Plasma (14)C-SCH 900518 concentrations were derived from the regression function established from the calibration standards, rather than directly from isotopic ratios from AMS measurement. The precision and accuracy of quality controls and calibration standards met the requirements of bioanalytical guidance (U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research, Center for Veterinary Medicine. Guidance for Industry: Bioanalytical Method Validation (ucm070107), May 2001. http://www.fda.gov/downloads/Drugs/GuidanceCompilanceRegulatoryInformation/Guidances/ucm070107.pdf ). The AMS measurement had a linear response range from 0.0159 to 9.07 dpm/mL for plasma (14)C-SCH 900158 concentrations. The CV and accuracy were 3.4-8.5% and 94-108% (82-119% for the lower limit of quantitation (LLOQ)), respectively, with a correlation coefficient of 0.9998. The absolute bioavailability was calculated from the dose-normalized area under the curve of iv and oral doses after the plasma concentrations were plotted vs the sampling time post oral dose. The mean absolute bioavailability of SCH 900518 was 40.8% (range 16.8-60.6%). The typical accuracy and standard deviation in AMS quantitative analysis of drugs from human plasma samples have been reported for the first time, and the impact of these

  10. An absolute photometric system at 10 and 20 microns

    NASA Technical Reports Server (NTRS)

    Rieke, G. H.; Lebofsky, M. J.; Low, F. J.

    1985-01-01

    Two new direct calibrations at 10 and 20 microns are presented in which terrestrial flux standards are referred to infrared standard stars. These measurements give both good agreement and higher accuracy when compared with previous direct calibrations. As a result, the absolute calibrations at 10 and 20 microns have now been determined with accuracies of 3 and 8 percent, respectively. A variety of absolute calibrations based on extrapolation of stellar spectra from the visible to 10 microns are reviewed. Current atmospheric models of A-type stars underestimate their fluxes by about 10 percent at 10 microns, whereas models of solar-type stars agree well with the direct calibrations. The calibration at 20 microns can probably be determined to about 5 percent by extrapolation from the more accurate result at 10 microns. The photometric system at 10 and 20 microns is updated to reflect the new absolute calibration, to base its zero point directly on the colors of A0 stars, and to improve the accuracy in the comparison of the standard stars.

  11. Absolute calibration of a three-axis SQUID-cascade vector magnetometer

    NASA Astrophysics Data System (ADS)

    Schönau, T.; Zakosarenko, V.; Schmelz, M.; Stolz, R.; Anders, S.; Linzen, S.; Meyer, M.; Faßbinder, J. W. E.; Meyer, H.-G.

    2017-01-01

    We report on the absolute calibration of a three-axis SQUID-cascade vector magnetometer suited for mobile operation in the Earth’s magnetic field. It is based on low temperature superconductor (LTS) dc SQUIDs with sub-micrometer sized cross-type Josephson junctions and exhibits a white noise level of about 10 fT Hz-1/2. Due to the cascaded operation principle, the huge dynamic range required to resolve a measurement range of more than 50 µT with sub-pT resolution is split onto several electronic channels of less demanding precision. As a result, the measurement accuracy is less vulnerable to parameter drifts. Furthermore, the intrinsic redundancy of the setup can be used to check for systematic errors of measurement. The offset as well as scaling and directional errors of the magnetometer have been obtained by the method of scalar calibration in our laboratory, resulting in a residuum with a standard deviation of less than 0.64 nT.

  12. Absolute air refractive index measurement and tracking based on variable length vacuum cell

    NASA Astrophysics Data System (ADS)

    Yu, Xiangzhi; Zhang, Tieli; Ellis, Jonathan D.

    2016-06-01

    A refractometer system using four modified Wu-type heterodyne interferometers with a variable length vacuum cell is presented. The proposed system has two working modes: (1) a moving mode for measuring the absolute air refractive index at the start of a measurement and (2) a static mode for monitoring the air refractive index fluctuation with the same bandwidth as a traditional displacement interferometer. The system requires no gas filling or pumping during the measurement and can be used for real-time refractive index compensation. Comparison experiments with empirical equations are conducted to investigate the feasibility and performance of the proposed system. The standard deviation of the measurement difference between the proposed system and empirical equation is 2.8 parts in 107, which is close to the uncertainty of our refractive index reference based on the accuracy of the environmental sensors. The relative refractive index tracking is a few parts in 108 with a bandwidth of 10 Hz, but high bandwidths are readily achievable.

  13. Absolute optical metrology : nanometers to kilometers

    NASA Technical Reports Server (NTRS)

    Dubovitsky, Serge; Lay, O. P.; Peters, R. D.; Liebe, C. C.

    2005-01-01

    We provide and overview of the developments in the field of high-accuracy absolute optical metrology with emphasis on space-based applications. Specific work on the Modulation Sideband Technology for Absolute Ranging (MSTAR) sensor is described along with novel applications of the sensor.

  14. ON A SUFFICIENT CONDITION FOR ABSOLUTE CONTINUITY.

    DTIC Science & Technology

    The formulation of a condition which yields absolute continuity when combined with continuity and bounded variation is the problem considered in the...Briefly, the formulation is achieved through a discussion which develops a proof by contradiction of a sufficiently theorem for absolute continuity which uses in its hypothesis the condition of continuity and bounded variation .

  15. Monolithically integrated absolute frequency comb laser system

    SciTech Connect

    Wanke, Michael C.

    2016-07-12

    Rather than down-convert optical frequencies, a QCL laser system directly generates a THz frequency comb in a compact monolithically integrated chip that can be locked to an absolute frequency without the need of a frequency-comb synthesizer. The monolithic, absolute frequency comb can provide a THz frequency reference and tool for high-resolution broad band spectroscopy.

  16. Absolute instability of the Gaussian wake profile

    NASA Technical Reports Server (NTRS)

    Hultgren, Lennart S.; Aggarwal, Arun K.

    1987-01-01

    Linear parallel-flow stability theory has been used to investigate the effect of viscosity on the local absolute instability of a family of wake profiles with a Gaussian velocity distribution. The type of local instability, i.e., convective or absolute, is determined by the location of a branch-point singularity with zero group velocity of the complex dispersion relation for the instability waves. The effects of viscosity were found to be weak for values of the wake Reynolds number, based on the center-line velocity defect and the wake half-width, larger than about 400. Absolute instability occurs only for sufficiently large values of the center-line wake defect. The critical value of this parameter increases with decreasing wake Reynolds number, thereby indicating a shrinking region of absolute instability with decreasing wake Reynolds number. If backflow is not allowed, absolute instability does not occur for wake Reynolds numbers smaller than about 38.

  17. 40 CFR 63.1965 - What is a deviation?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 12 2010-07-01 2010-07-01 true What is a deviation? 63.1965 Section 63.1965 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED... Requirements § 63.1965 What is a deviation? A deviation is defined in § 63.1990. For the purposes of...

  18. 21 CFR 330.11 - NDA deviations from applicable monograph.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false NDA deviations from applicable monograph. 330.11... EFFECTIVE AND NOT MISBRANDED Administrative Procedures § 330.11 NDA deviations from applicable monograph. A new drug application requesting approval of an OTC drug deviating in any respect from a monograph...

  19. 9 CFR 318.308 - Deviations in processing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY...) Deviations in processing (or process deviations) must be handled according to: (1)(i) A HACCP plan for canned...) of this section. (c) (d) Procedures for handling process deviations where the HACCP plan...

  20. Establishing ion ratio thresholds based on absolute peak area for absolute protein quantification using protein cleavage isotope dilution mass spectrometry.

    PubMed

    Loziuk, Philip L; Sederoff, Ronald R; Chiang, Vincent L; Muddiman, David C

    2014-11-07

    Quantitative mass spectrometry has become central to the field of proteomics and metabolomics. Selected reaction monitoring is a widely used method for the absolute quantification of proteins and metabolites. This method renders high specificity using several product ions measured simultaneously. With growing interest in quantification of molecular species in complex biological samples, confident identification and quantitation has been of particular concern. A method to confirm purity or contamination of product ion spectra has become necessary for achieving accurate and precise quantification. Ion abundance ratio assessments were introduced to alleviate some of these issues. Ion abundance ratios are based on the consistent relative abundance (RA) of specific product ions with respect to the total abundance of all product ions. To date, no standardized method of implementing ion abundance ratios has been established. Thresholds by which product ion contamination is confirmed vary widely and are often arbitrary. This study sought to establish criteria by which the relative abundance of product ions can be evaluated in an absolute quantification experiment. These findings suggest that evaluation of the absolute ion abundance for any given transition is necessary in order to effectively implement RA thresholds. Overall, the variation of the RA value was observed to be relatively constant beyond an absolute threshold ion abundance. Finally, these RA values were observed to fluctuate significantly over a 3 year period, suggesting that these values should be assessed as close as possible to the time at which data is collected for quantification.

  1. Absolute realization of low BRDF value

    NASA Astrophysics Data System (ADS)

    Liu, Zilong; Liao, Ningfang; Li, Ping; Wang, Yu

    2010-10-01

    Low BRDF value is widespread used in many critical domains such as space and military fairs. These values below 0.1 Sr-1 . So the Absolute realization of these value is the most critical issue in the absolute measurement of BRDF. To develop the Absolute value realization theory of BRDF , defining an arithmetic operators of BRDF , achieving an absolute measurement Eq. of BRDF based on radiance. This is a new theory method to solve the realization problem of low BRDF value. This theory method is realized on a self-designed common double orientation structure in space. By designing an adding structure to extend the range of the measurement system and a control and processing software, Absolute realization of low BRDF value is achieved. A material of low BRDF value is measured in this measurement system and the spectral BRDF value are showed within different angles allover the space. All these values are below 0.4 Sr-1 . This process is a representative procedure about the measurement of low BRDF value. A corresponding uncertainty analysis of this measurement data is given depend on the new theory of absolute realization and the performance of the measurement system. The relative expand uncertainty of the measurement data is 0.078. This uncertainty analysis is suitable for all measurements using the new theory of absolute realization and the corresponding measurement system.

  2. Temperature deviation index and elderly mortality in Japan.

    PubMed

    Lim, Youn-Hee; Reid, Colleen E; Honda, Yasushi; Kim, Ho

    2016-07-01

    Few studies have examined how the precedence of abnormal temperatures in previous neighboring years affects the population's health. In the present study, we attempted to quantify the health effects of abnormal weather patterns by creating a metric called the temperature deviation index (TDI) and estimated the effects of TDI on mortality in Japan. We used data from 47 prefectures in Japan to compute the TDI on days between May and September from 1966 to 2010. The TDI is a summed product of an indicator of absence of high temperatures in the neighboring years, and more weights were assigned to the years closest to the current year. To estimate the TDI effects on elderly mortality, we used generalized linear modeling with a Poisson distribution after adjusting for apparent temperature, barometric pressure, day of the week, and time trend. For each prefecture, we estimated the TDI effects and pooled the estimates to yield a national average for 1991-2010 in Japan. The estimated effects of TDI in middle- or high-latitude prefectures were greater than in low-latitude prefectures. The estimated national average of TDI effects was a 0.5 % (95 % confidence intervals [CI], 0.1, 1.0) increase in elderly mortality per 1-unit (around 1 standard deviation) increase in the TDI. The significant pooled estimation of TDI effects was mainly due to the TDI effects on summer days with moderate temperature (25th-49th percentile, mean temperature 22.9 °C): a 1.9 % (95 % CI, 1.1, 2.6) increase in elderly mortality per 1-unit increase in the TDI. However, TDI effects were insignificant in other temperature ranges. These findings suggest that elderly deaths increased on moderate temperature days in the summer that differed substantially from days during that time window in the neighboring years. Therefore, not only high temperature itself but also temperature deviation compared to previous years could be considered to be a risk factor for elderly mortality in the summer.

  3. Temperature deviation index and elderly mortality in Japan

    NASA Astrophysics Data System (ADS)

    Lim, Youn-Hee; Reid, Colleen E.; Honda, Yasushi; Kim, Ho

    2016-07-01

    Few studies have examined how the precedence of abnormal temperatures in previous neighboring years affects the population's health. In the present study, we attempted to quantify the health effects of abnormal weather patterns by creating a metric called the temperature deviation index (TDI) and estimated the effects of TDI on mortality in Japan. We used data from 47 prefectures in Japan to compute the TDI on days between May and September from 1966 to 2010. The TDI is a summed product of an indicator of absence of high temperatures in the neighboring years, and more weights were assigned to the years closest to the current year. To estimate the TDI effects on elderly mortality, we used generalized linear modeling with a Poisson distribution after adjusting for apparent temperature, barometric pressure, day of the week, and time trend. For each prefecture, we estimated the TDI effects and pooled the estimates to yield a national average for 1991-2010 in Japan. The estimated effects of TDI in middle- or high-latitude prefectures were greater than in low-latitude prefectures. The estimated national average of TDI effects was a 0.5 % (95 % confidence intervals [CI], 0.1, 1.0) increase in elderly mortality per 1-unit (around 1 standard deviation) increase in the TDI. The significant pooled estimation of TDI effects was mainly due to the TDI effects on summer days with moderate temperature (25th-49th percentile, mean temperature 22.9 °C): a 1.9 % (95 % CI, 1.1, 2.6) increase in elderly mortality per 1-unit increase in the TDI. However, TDI effects were insignificant in other temperature ranges. These findings suggest that elderly deaths increased on moderate temperature days in the summer that differed substantially from days during that time window in the neighboring years. Therefore, not only high temperature itself but also temperature deviation compared to previous years could be considered to be a risk factor for elderly mortality in the summer.

  4. Well tractors for highly deviated and horizontal wells

    SciTech Connect

    Hallundbaek, J.

    1994-12-31

    This paper introduces the oil industry to a new type of downhole tools--the Well Tractors with modular power source designed for running in open hole and inside the completions of horizontal and highly deviated wells. The Well Tractors are used for cleaning, setting and pulling of plugs, operating sliding sleeves, open hole logging, running of production logs, drilling, perforation guns, cement bond logs, etc. Horizontally the Well Tractors pull coiled tubing and/or wireline beyond 10,000 ft. The Well Tractors are capable of pulling more than 25,000 ft of coiled tubing and/or wireline into a highly deviated well. Furthermore the tools are designed for pushing other tools into the hole, e.g., logging tools, video cameras, etc. The Well Tractors with modular power source are designed in two versions: A fluid driven version for coiled tubing operations, powered by brine, water, mud, etc., which is pumped down through standard coiled tubing. The tool is controlled from the surface via a wireline running inside the tubing. Through the wireline measurements can be transmitted to the surface. Alternatively the tool can also operate without the wireline which enables it to run with a smaller size of coiled tubing or have a higher flow rate for cleaning jobs. An electric driven version of the Well Tractor for wireline operations, powered and controlled through the wireline. The Well Tractors are designed in 3 different sizes. A Tractor with an outside diameter of 3 1/8 in. A Tractor with an outside diameter of 4 3/4 in. and a Tractor with an outside diameter of 2 1/8 in.

  5. Constraints on deviations from ΛCDM within Horndeski gravity

    SciTech Connect

    Bellini, Emilio; Cuesta, Antonio J.; Jimenez, Raul; Verde, Licia E-mail: ajcuesta@icc.ub.edu E-mail: liciaverde@icc.ub.edu

    2016-02-01

    Recent anomalies found in cosmological datasets such as the low multipoles of the Cosmic Microwave Background or the low redshift amplitude and growth of clustering measured by e.g., abundance of galaxy clusters and redshift space distortions in galaxy surveys, have motivated explorations of models beyond standard ΛCDM. Of particular interest are models where general relativity (GR) is modified on large cosmological scales. Here we consider deviations from ΛCDM+GR within the context of Horndeski gravity, which is the most general theory of gravity with second derivatives in the equations of motion. We adopt a parametrization in which the four additional Horndeski functions of time α{sub i}(t) are proportional to the cosmological density of dark energy Ω{sub DE}(t). Constraints on this extended parameter space using a suite of state-of-the art cosmological observations are presented for the first time. Although the theory is able to accommodate the low multipoles of the Cosmic Microwave Background and the low amplitude of fluctuations from redshift space distortions, we find no significant tension with ΛCDM+GR when performing a global fit to recent cosmological data and thus there is no evidence against ΛCDM+GR from an analysis of the value of the Bayesian evidence ratio of the modified gravity models with respect to ΛCDM, despite introducing extra parameters. The posterior distribution of these extra parameters that we derive return strong constraints on any possible deviations from ΛCDM+GR in the context of Horndeski gravity. We illustrate how our results can be applied to a more general frameworks of modified gravity models.

  6. Neutron activation analysis of certified samples by the absolute method

    NASA Astrophysics Data System (ADS)

    Kadem, F.; Belouadah, N.; Idiri, Z.

    2015-07-01

    The nuclear reactions analysis technique is mainly based on the relative method or the use of activation cross sections. In order to validate nuclear data for the calculated cross section evaluated from systematic studies, we used the neutron activation analysis technique (NAA) to determine the various constituent concentrations of certified samples for animal blood, milk and hay. In this analysis, the absolute method is used. The neutron activation technique involves irradiating the sample and subsequently performing a measurement of the activity of the sample. The fundamental equation of the activation connects several physical parameters including the cross section that is essential for the quantitative determination of the different elements composing the sample without resorting to the use of standard sample. Called the absolute method, it allows a measurement as accurate as the relative method. The results obtained by the absolute method showed that the values are as precise as the relative method requiring the use of standard sample for each element to be quantified.

  7. Networks of Absolute Calibration Stars for SST, AKARI, and WISE

    NASA Astrophysics Data System (ADS)

    Cohen, M.

    2007-04-01

    I describe the Cohen-Walker-Witteborn (CWW) network of absolute calibration stars built to support ground-based, airborne, and space-based sensors, and how they are used to calibrate instruments on the SPITZER Space Telescope (SST and Japan's AKARI (formerly ASTRO-F), and to support NASA's planned MidEx WISE (the Wide-field Infrared Survey Explorer). All missions using this common calibration share a self-consistent framework embracing photometry and low-resolution spectroscopy. CWW also underpins COBE/DIRBE several instruments used on the Kuiper Airborne Observatory ({KAO}), the joint Japan-USA ``IR Telescope in Space" (IRTS) Near-IR and Mid-IR spectrometers, the European Space Agency's IR Space Observatory (ISO), and the US Department of Defense's Midcourse Space eXperiment (MSX). This calibration now spans the far-UV to mid-infrared range with Sirius (one specific Kurucz synthetic spectrum) as basis, and zero magnitude defined from another Kurucz spectrum intended to represent an ideal Vega (not the actual star with its pole-on orientation and mid-infrared dust excess emission). Precision 4-29 μm radiometric measurements on MSX validate CWW's absolute Kurucz spectrum of Sirius, the primary, and a set of bright K/MIII secondary standards. Sirius is measured to be 1.0% higher than predicted. CWW's definitions of IR zero magnitudes lie within 1.1% absolute of MSX measurements. The US Air Force Research Laboratory's independent analysis of on-orbit {MSX} stellar observations compared with emissive reference spheres show CWW primary and empirical secondary spectra lie well within the ±1.45% absolute uncertainty associated with this 15-year effort. Our associated absolute calibration for the InfraRed Array Camera (IRAC) on the SST lies within ˜2% of the recent extension of the calibration of the Hubble Space Telescope's STIS instrument to NICMOS (Bohlin, these Proceedings), showing the closeness of these two independent approaches to calibration.

  8. The possibility of constructing the hydrogen scale of the absolute atomic masses of the elements

    NASA Astrophysics Data System (ADS)

    Kuz'min, I. I.

    2009-12-01

    The paper presents a scheme for the experimental-empirical construction of the existing chemical, physical, and carbon scales of the relative nonintegral atomic masses of the elements. The quantitative interrelation between the nonintegral relative atomic masses, their minimized fractional positive and negative natural deviations from integral numbers, and their integral parts are reproduced mathematically. Nonisotopic fractional deviations are shown to be a consequence of methodological side effects of the scheme for theoretical processing of the data of thorough physical and chemical measurements performed by Stas and Aston in constructing scales of relative atomic masses. In conformity with the Prout hypothesis, the absolute atomic mass unit and the corresponding Avogadro’s number value are suggested for the construction of the hydrogen scale of absolute atomic masses of nonisotopic elements, individual isotopes, and isotope-containing elements.

  9. Consistent set of nuclear parameters values for absolute INAA

    SciTech Connect

    Heft, R.E.

    1980-01-01

    Gamma spectral analysis of irradiated material can be used to determine absolute disintegration rates for specific radionuclides. These data, together with measured values for the thermal and epithermal neutron fluxes, and irradiation, cooling and counting time values, are all the experimental information required to do absolute Instrumental Neutron Activation Analysis. The calculations required to go from product photon emission rate to target nuclide amount depend upon values used for the thermal neutron capture cross-section, the resonance absorption integral, the half-life and photon branching ratios. Values for these parameters were determined by irradiating and analyzing a series of elemental standards. The results of these measurements were combined with values reported by other workers to arrive at a set of recommended values for the constants. Values for 114 nuclides are listed.

  10. Comparisons of absolute gravimeters (COOMET.M.G-S1)

    NASA Astrophysics Data System (ADS)

    Vinnichenko, Mr Alexander; Germak, Alessandro, Dr

    2017-01-01

    This report describes the results of the RMO supplementary comparison COOMET.M.G-S1 (also known as bilateral comparison COOMET 634/UA/14). The comparison measurements between the two participants NSC 'IM' (pilot laboratory) and INRIM were started in December 2015 and finished in January 2016. Participants of comparisons were conducted at their national standards the measurements of the free fall acceleration in gravimetric point laboratory of absolute gravimetry of INRIM named INRiM.2. Absolute measurements of gravimetric acceleration were conducted by ballistic gravimeters. The agreement between the two participants is good. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  11. Self consistent, absolute calibration technique for photon number resolving detectors.

    PubMed

    Avella, A; Brida, G; Degiovanni, I P; Genovese, M; Gramegna, M; Lolli, L; Monticone, E; Portesi, C; Rajteri, M; Rastello, M L; Taralli, E; Traina, P; White, M

    2011-11-07

    Well characterized photon number resolving detectors are a requirement for many applications ranging from quantum information and quantum metrology to the foundations of quantum mechanics. This prompts the necessity for reliable calibration techniques at the single photon level. In this paper we propose an innovative absolute calibration technique for photon number resolving detectors, using a pulsed heralded photon source based on parametric down conversion. The technique, being absolute, does not require reference standards and is independent upon the performances of the heralding detector. The method provides the results of quantum efficiency for the heralded detector as a function of detected photon numbers. Furthermore, we prove its validity by performing the calibration of a Transition Edge Sensor based detector, a real photon number resolving detector that has recently demonstrated its effectiveness in various quantum information protocols.

  12. 49 CFR 192.943 - When can an operator deviate from these reassessment intervals?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Gas Transmission Pipeline Integrity Management § 192.943 When can an operator deviate from these...

  13. 49 CFR 192.943 - When can an operator deviate from these reassessment intervals?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Gas Transmission Pipeline Integrity Management § 192.943 When can an operator deviate from these...

  14. 49 CFR 192.943 - When can an operator deviate from these reassessment intervals?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Gas Transmission Pipeline Integrity Management § 192.943 When can an operator deviate from these...

  15. 49 CFR 192.943 - When can an operator deviate from these reassessment intervals?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Gas Transmission Pipeline Integrity Management § 192.943 When can an operator deviate from these...

  16. 49 CFR 192.943 - When can an operator deviate from these reassessment intervals?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... (Continued) PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF NATURAL AND OTHER GAS BY PIPELINE: MINIMUM FEDERAL SAFETY STANDARDS Gas Transmission Pipeline Integrity Management § 192.943 When can an operator deviate from these...

  17. MUSiC - An Automated Scan for Deviations between Data and Monte Carlo Simulation

    SciTech Connect

    Meyer, Arnd

    2010-02-10

    A model independent analysis approach is presented, systematically scanning the data for deviations from the standard model Monte Carlo expectation. Such an analysis can contribute to the understanding of the CMS detector and the tuning of event generators. The approach is sensitive to a variety of models of new physics, including those not yet thought of.

  18. A New Gimmick for Assigning Absolute Configuration.

    ERIC Educational Resources Information Center

    Ayorinde, F. O.

    1983-01-01

    A five-step procedure is provided to help students in making the assignment absolute configuration less bothersome. Examples for both single (2-butanol) and multi-chiral carbon (3-chloro-2-butanol) molecules are included. (JN)

  19. Magnifying absolute instruments for optically homogeneous regions

    SciTech Connect

    Tyc, Tomas

    2011-09-15

    We propose a class of magnifying absolute optical instruments with a positive isotropic refractive index. They create magnified stigmatic images, either virtual or real, of optically homogeneous three-dimensional spatial regions within geometrical optics.

  20. The Simplicity Argument and Absolute Morality

    ERIC Educational Resources Information Center

    Mijuskovic, Ben

    1975-01-01

    In this paper the author has maintained that there is a similarity of thought to be found in the writings of Cudworth, Emerson, and Husserl in his investigation of an absolute system of morality. (Author/RK)

  1. THE ABSOLUTE MAGNITUDES OF TYPE Ia SUPERNOVAE IN THE ULTRAVIOLET

    SciTech Connect

    Brown, Peter J.; Roming, Peter W. A.; Ciardullo, Robin; Gronwall, Caryl; Hoversten, Erik A.; Pritchard, Tyler; Milne, Peter; Bufano, Filomena; Mazzali, Paolo; Elias-Rosa, Nancy; Filippenko, Alexei V.; Li Weidong; Foley, Ryan J.; Hicken, Malcolm; Kirshner, Robert P.; Gehrels, Neil; Holland, Stephen T.; Immler, Stefan; Phillips, Mark M.; Still, Martin

    2010-10-01

    We examine the absolute magnitudes and light-curve shapes of 14 nearby (redshift z = 0.004-0.027) Type Ia supernovae (SNe Ia) observed in the ultraviolet (UV) with the Swift Ultraviolet/Optical Telescope. Colors and absolute magnitudes are calculated using both a standard Milky Way extinction law and one for the Large Magellanic Cloud that has been modified by circumstellar scattering. We find very different behavior in the near-UV filters (uvw1{sub rc} covering {approx}2600-3300 A after removing optical light, and u {approx} 3000-4000 A) compared to a mid-UV filter (uvm2 {approx}2000-2400 A). The uvw1{sub rc} - b colors show a scatter of {approx}0.3 mag while uvm2-b scatters by nearly 0.9 mag. Similarly, while the scatter in colors between neighboring filters is small in the optical and somewhat larger in the near-UV, the large scatter in the uvm2 - uvw1 colors implies significantly larger spectral variability below 2600 A. We find that in the near-UV the absolute magnitudes at peak brightness of normal SNe Ia in our sample are correlated with the optical decay rate with a scatter of 0.4 mag, comparable to that found for the optical in our sample. However, in the mid-UV the scatter is larger, {approx}1 mag, possibly indicating differences in metallicity. We find no strong correlation between either the UV light-curve shapes or the UV colors and the UV absolute magnitudes. With larger samples, the UV luminosity might be useful as an additional constraint to help determine distance, extinction, and metallicity in order to improve the utility of SNe Ia as standardized candles.

  2. Crystal structure of meteoritic schreibersites: determination of absolute structure

    NASA Astrophysics Data System (ADS)

    Skála, Roman; Císařová, Ivana

    Minerals of the schreibersite nickelphosphide series (Fe,Ni)3P crystallize in the non-centrosymmetric space group Ibar 4. As a consequence, they can possess two different spatial arrangements of the constituting atoms within the unit cell, related by the inversion symmetry operation. Here, we present the crystal structure refinements from single crystal X-ray diffraction data for schreibersite grains from iron meteorites Acuña, Carlton, Hex River Mts. (three different crystals), Odessa (two different crystals), Sikhote Alin, and Toluca aiming for the determination of the absolute structure of the examined crystals. The crystals studied cover the composition range from 58 mol% to 80 mol% Fe3P end-member. Unit-cell parameter a and volume of the unit cell V, as well as certain topological structural parameters tightly correlate with Fe3P content. Unit-cell parameter c, on the other hand, does not show such strong correlation. Eight of the nine crystal structure refinements allowed unambiguous absolute structure assignment. The single crystal extracted from Toluca is, however, of poor quality and consequently the structure refinement did not provide as good results as the rest of the materials. Also, this crystal has only weak inversion distinguishing power to provide unequivocal absolute structure determination. Six of the eight unambiguous absolute structure determinations indicated inverted atomic arrangement compared to that reported in earlier structure refinements (here called standard). Only two grains, one taken from Odessa iron and the other from the Hex River Mts. meteorite, reveal the dominance of standard crystal structure setting.

  3. Deviation of the fully protracted tongue: is it a reliable indicator for language cerebral dominance?

    PubMed

    Abu Ghaida, Jamaledin; Hani, Saleh Bani; Mustafa, Ayman; Eldwairi, Qasim

    2014-09-01

    Since its introduction in 1960, The Wada test has been considered the gold standard for language lateralization prior to ablative brain surgery. Due to the invasive nature of The Wada test several non-invasive techniques have been alternatively adopted. Recently, it has been suggested that the tongue deviates toward the language dominant cerebral hemisphere on full protraction. This suggestion is based on the important role the tongue plays in articulation and on the close anatomical relationship between the cortical tongue motor area and the motor speech area. It was proposed that this phenomenon could serve as a reliable and simple method for language brain lateralization. However, this hypothesis is still open for verification. In an attempt to correlate tongue deviation and language cerebral dominance we present and discuss in this paper the results of a study conducted on 339 free adult Jordanian volunteers. Tongue deviation and handedness were determined and statistically correlated. Our results showed that 62% of test subjects did not show any tongue deviation on full protrusion. Additionally, 9% of test subjects showed left-sided tongue deviation on full protraction in spite of 90% right handedness with presumed left language dominant cerebral hemisphere. We conclude that, at least in Jordanians, tongue deviation cannot be considered as a reliable indicator for language lateralization.

  4. Absolute cross sections of compound nucleus reactions

    NASA Astrophysics Data System (ADS)

    Capurro, O. A.

    1993-11-01

    The program SEEF is a Fortran IV computer code for the extraction of absolute cross sections of compound nucleus reactions. When the evaporation residue is fed by its parents, only cumulative cross sections will be obtained from off-line gamma ray measurements. But, if one has the parent excitation function (experimental or calculated), this code will make it possible to determine absolute cross sections of any exit channel.

  5. Kelvin and the absolute temperature scale

    NASA Astrophysics Data System (ADS)

    Erlichson, Herman

    2001-07-01

    This paper describes the absolute temperature scale of Kelvin (William Thomson). Kelvin found that Carnot's axiom about heat being a conserved quantity had to be abandoned. Nevertheless, he found that Carnot's fundamental work on heat engines was correct. Using the concept of a Carnot engine Kelvin found that Q1/Q2 = T1/T2. Thermometers are not used to obtain absolute temperatures since they are calculated temperatures.

  6. LD-SPatt: large deviations statistics for patterns on Markov chains.

    PubMed

    Nuel, G

    2004-01-01

    Statistics on Markov chains are widely used for the study of patterns in biological sequences. Statistics on these models can be done through several approaches. Central limit theorem (CLT) producing Gaussian approximations are one of the most popular ones. Unfortunately, in order to find a pattern of interest, these methods have to deal with tail distribution events where CLT is especially bad. In this paper, we propose a new approach based on the large deviations theory to assess pattern statistics. We first recall theoretical results for empiric mean (level 1) as well as empiric distribution (level 2) large deviations on Markov chains. Then, we present the applications of these results focusing on numerical issues. LD-SPatt is the name of GPL software implementing these algorithms. We compare this approach to several existing ones in terms of complexity and reliability and show that the large deviations are more reliable than the Gaussian approximations in absolute values as well as in terms of ranking and are at least as reliable as compound Poisson approximations. We then finally discuss some further possible improvements and applications of this new method.

  7. Validation of Mean Absolute Sea Level of the North Atlantic obtained from Drifter, Altimetry and Wind Data

    NASA Technical Reports Server (NTRS)

    Maximenko, Nikolai A.

    2003-01-01

    Mean absolute sea level reflects the deviation of the Ocean surface from geoid due to the ocean currents and is an important characteristic of the dynamical state of the ocean. Values of its spatial variations (order of 1 m) are generally much smaller than deviations of the geoid shape from ellipsoid (order of 100 m) that makes the derivation of the absolute mean sea level a difficult task for gravity and satellite altimetry observations. Technique used by Niiler et al. for computation of the absolute mean sea level in the Kuroshio Extension was then developed into more general method and applied by Niiler et al. (2003b) to the global Ocean. The method is based on the consideration of balance of horizontal momentum.

  8. Predicting Absolute Risk of Type 2 Diabetes Using Age and Waist Circumference Values in an Aboriginal Australian Community

    PubMed Central

    2015-01-01

    Objectives To predict in an Australian Aboriginal community, the 10-year absolute risk of type 2 diabetes associated with waist circumference and age on baseline examination. Method A sample of 803 diabetes-free adults (82.3% of the age-eligible population) from baseline data of participants collected from 1992 to 1998 were followed-up for up to 20 years till 2012. The Cox-proportional hazard model was used to estimate the effects of waist circumference and other risk factors, including age, smoking and alcohol consumption status, of males and females on prediction of type 2 diabetes, identified through subsequent hospitalisation data during the follow-up period. The Weibull regression model was used to calculate the absolute risk estimates of type 2 diabetes with waist circumference and age as predictors. Results Of 803 participants, 110 were recorded as having developed type 2 diabetes, in subsequent hospitalizations over a follow-up of 12633.4 person-years. Waist circumference was strongly associated with subsequent diagnosis of type 2 diabetes with P<0.0001 for both genders and remained statistically significant after adjusting for confounding factors. Hazard ratios of type 2 diabetes associated with 1 standard deviation increase in waist circumference were 1.7 (95%CI 1.3 to 2.2) for males and 2.1 (95%CI 1.7 to 2.6) for females. At 45 years of age with baseline waist circumference of 100 cm, a male had an absolute diabetic risk of 10.9%, while a female had a 14.3% risk of the disease. Conclusions The constructed model predicts the 10-year absolute diabetes risk in an Aboriginal Australian community. It is simple and easily understood and will help identify individuals at risk of diabetes in relation to waist circumference values. Our findings on the relationship between waist circumference and diabetes on gender will be useful for clinical consultation, public health education and establishing WC cut-off points for Aboriginal Australians. PMID:25876058

  9. Jasminum flexile flower absolute from India--a detailed comparison with three other jasmine absolutes.

    PubMed

    Braun, Norbert A; Kohlenberg, Birgit; Sim, Sherina; Meier, Manfred; Hammerschmidt, Franz-Josef

    2009-09-01

    Jasminum flexile flower absolute from the south of India and the corresponding vacuum headspace (VHS) sample of the absolute were analyzed using GC and GC-MS. Three other commercially available Indian jasmine absolutes from the species: J. sambac, J. officinale subsp. grandiflorum, and J. auriculatum and the respective VHS samples were used for comparison purposes. One hundred and twenty-one compounds were characterized in J. flexile flower absolute, with methyl linolate, benzyl salicylate, benzyl benzoate, (2E,6E)-farnesol, and benzyl acetate as the main constituents. A detailed olfactory evaluation was also performed.

  10. On measuring the absolute scale of baryon acoustic oscillations

    NASA Astrophysics Data System (ADS)

    Sutherland, Will

    2012-10-01

    The baryon acoustic oscillation (BAO) feature in the distribution of galaxies provides a fundamental standard ruler which is widely used to constrain cosmological parameters. In most analyses, the comoving length of the ruler is inferred from a combination of cosmic microwave background (CMB) observations and theory. However, this inferred length may be biased by various non-standard effects in early universe physics; this can lead to biased inferences of cosmological parameters such as H0, Ωm and w, so it would be valuable to measure the absolute BAO length by combining a galaxy redshift survey and a suitable direct low-z distance measurement. One obstacle is that low-redshift BAO surveys mainly constrain the ratio rS/DV(z), where DV is a dilation scale which is not directly observable by standard candles. Here, we find a new approximation DV(z)≃34DL(43z)(1+43z)-1(1-0.02455 z3+0.0105 z4) which connects DV to the standard luminosity distance DL at a somewhat higher redshift; this is shown to be very accurate (relative error <0.2 per cent) for all Wilkinson Microwave Anisotropy Probe compatible Friedmann models at z < 0.4, with very weak dependence on cosmological parameters H0, Ωm, Ωk, w. This provides a route to measure the absolute BAO length using only observations at z ≲ 0.3, including Type Ia supernovae, and potentially future H0-free physical distance indicators such as gravitational lenses or gravitational wave standard sirens. This would provide a zero-parameter check of the standard cosmology at 103 ≲ z ≲ 105, and can constrain the number of relativistic species Neff with fewer degeneracies than the CMB.

  11. Universal Cosmic Absolute and Modern Science

    NASA Astrophysics Data System (ADS)

    Kostro, Ludwik

    The official Sciences, especially all natural sciences, respect in their researches the principle of methodic naturalism i.e. they consider all phenomena as entirely natural and therefore in their scientific explanations they do never adduce or cite supernatural entities and forces. The purpose of this paper is to show that Modern Science has its own self-existent, self-acting, and self-sufficient Natural All-in Being or Omni-Being i.e. the entire Nature as a Whole that justifies the scientific methodic naturalism. Since this Natural All-in Being is one and only It should be considered as the own scientifically justified Natural Absolute of Science and should be called, in my opinion, the Universal Cosmic Absolute of Modern Science. It will be also shown that the Universal Cosmic Absolute is ontologically enormously stratified and is in its ultimate i.e. in its most fundamental stratum trans-reistic and trans-personal. It means that in its basic stratum. It is neither a Thing or a Person although It contains in Itself all things and persons with all other sentient and conscious individuals as well, On the turn of the 20th century the Science has begun to look for a theory of everything, for a final theory, for a master theory. In my opinion the natural Universal Cosmic Absolute will constitute in such a theory the radical all penetrating Ultimate Basic Reality and will substitute step by step the traditional supernatural personal Absolute.

  12. Adverse Drug Reactions and quality deviations monitored by spontaneous reports

    PubMed Central

    Visacri, Marília Berlofa; de Souza, Cinthia Madeira; Sato, Catarina Miyako Shibata; Granja, Silvia; de Marialva, Mécia; Mazzola, Priscila Gava; Moriel, Patricia

    2014-01-01

    Objectives The aim of this study was to determine the frequency and profile of spontaneous reports of Adverse Drug Reactions (ADRs) and quality deviations in a Brazilian teaching hospital and propose a consistent classification to study quality deviations. Methods This is a descriptive and retrospective study involving the analysis of spontaneous reports of ADRs and quality deviations in 2010. ADRs were classified according to the reaction mechanism, severity, and causality. The drugs were classified according to their therapeutic classes and symptoms according to the affected organ. The quality deviations were classified according to the type of deviation and type of medicine available in the Brazilian market. Results A total of 68 forms were examined; ADRs accounted for 39.7% of the notifications, while quality deviations accounted for 60.3%. ADRs occurred more frequently in men (51.9%) and adults (63.0%). The skin (28.0%) was the most affected organ, while anti-infectives (40.7%) were the therapeutic class that caused the most ADRs. The most common ADRs were type B (74.0%), moderates (37.0%), and probables (55.6%). In relation to quality deviations, the most frequent notifications were breaks, splits and leaks (20.9%) and related to generic drugs (43.9%). Conclusion The classification system to study quality deviations was clear and consistent. This study demonstrated that practices and public policies related to more effective pharmacovigilance need to be implemented so that the number of spontaneous reports increases. PMID:25972731

  13. 45 CFR 63.19 - Budget revisions and minor deviations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 1 2014-10-01 2014-10-01 false Budget revisions and minor deviations. 63.19 Section 63.19 Public Welfare Department of Health and Human Services GENERAL ADMINISTRATION GRANT PROGRAMS... Budget revisions and minor deviations. Pursuant to § 74.102(d) of this title, paragraphs (b)(3) and...

  14. 45 CFR 63.19 - Budget revisions and minor deviations.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 45 Public Welfare 1 2012-10-01 2012-10-01 false Budget revisions and minor deviations. 63.19 Section 63.19 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION GRANT PROGRAMS... Budget revisions and minor deviations. Pursuant to § 74.102(d) of this title, paragraphs (b)(3) and...

  15. 45 CFR 63.19 - Budget revisions and minor deviations.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 1 2013-10-01 2013-10-01 false Budget revisions and minor deviations. 63.19 Section 63.19 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION GRANT PROGRAMS... Budget revisions and minor deviations. Pursuant to § 74.102(d) of this title, paragraphs (b)(3) and...

  16. 41 CFR 109-1.110-50 - Deviation procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... number(s) of the DOE-PMR; (2) The reason why the deviation is considered necessary or would be in the...) Requests for deviations from applicable portions of the FPMR and DOE-PMR (except aviation related portions... related portions of the FPMR and DOE-PMR concerning aviation operations shall be forwarded by the OPMO...

  17. 41 CFR 101-42.002 - Requests for deviations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... DISPOSAL OF HAZARDOUS MATERIALS AND CERTAIN CATEGORIES OF PROPERTY § 101-42.002 Requests for deviations... 41 Public Contracts and Property Management 2 2014-07-01 2012-07-01 true Requests for deviations. 101-42.002 Section 101-42.002 Public Contracts and Property Management Federal Property...

  18. 41 CFR 101-42.002 - Requests for deviations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... DISPOSAL OF HAZARDOUS MATERIALS AND CERTAIN CATEGORIES OF PROPERTY § 101-42.002 Requests for deviations... 41 Public Contracts and Property Management 2 2012-07-01 2012-07-01 false Requests for deviations. 101-42.002 Section 101-42.002 Public Contracts and Property Management Federal Property...

  19. 41 CFR 101-42.002 - Requests for deviations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... DISPOSAL OF HAZARDOUS MATERIALS AND CERTAIN CATEGORIES OF PROPERTY § 101-42.002 Requests for deviations... 41 Public Contracts and Property Management 2 2013-07-01 2012-07-01 true Requests for deviations. 101-42.002 Section 101-42.002 Public Contracts and Property Management Federal Property...

  20. 41 CFR 101-42.002 - Requests for deviations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... DISPOSAL OF HAZARDOUS MATERIALS AND CERTAIN CATEGORIES OF PROPERTY § 101-42.002 Requests for deviations... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true Requests for deviations. 101-42.002 Section 101-42.002 Public Contracts and Property Management Federal Property...

  1. 41 CFR 101-42.002 - Requests for deviations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... DISPOSAL OF HAZARDOUS MATERIALS AND CERTAIN CATEGORIES OF PROPERTY § 101-42.002 Requests for deviations... 41 Public Contracts and Property Management 2 2011-07-01 2007-07-01 true Requests for deviations. 101-42.002 Section 101-42.002 Public Contracts and Property Management Federal Property...

  2. 33 CFR 164.51 - Deviations from rules: Emergency.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Deviations from rules: Emergency. 164.51 Section 164.51 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY NAVIGATION SAFETY REGULATIONS § 164.51 Deviations from...

  3. 33 CFR 164.51 - Deviations from rules: Emergency.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Deviations from rules: Emergency. 164.51 Section 164.51 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PORTS AND WATERWAYS SAFETY NAVIGATION SAFETY REGULATIONS § 164.51 Deviations from...

  4. Refraction in Terms of the Deviation of the Light.

    ERIC Educational Resources Information Center

    Goldberg, Fred M.

    1985-01-01

    Discusses refraction in terms of the deviation of light. Points out that in physics courses where very little mathematics is used, it might be more suitable to describe refraction entirely in terms of the deviation, rather than by introducing Snell's law. (DH)

  5. 38 CFR 36.4304 - Deviations; changes of identity.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... identity. 36.4304 Section 36.4304 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS... Deviations; changes of identity. A deviation of more than 5 percent between the estimates upon which a... change in the identity of the property upon which the original appraisal was based, will invalidate...

  6. 38 CFR 36.4304 - Deviations; changes of identity.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... identity. 36.4304 Section 36.4304 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS... Deviations; changes of identity. A deviation of more than 5 percent between the estimates upon which a... change in the identity of the property upon which the original appraisal was based, will invalidate...

  7. 38 CFR 36.4304 - Deviations; changes of identity.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... identity. 36.4304 Section 36.4304 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS... Deviations; changes of identity. A deviation of more than 5 percent between the estimates upon which a... change in the identity of the property upon which the original appraisal was based, will invalidate...

  8. 38 CFR 36.4304 - Deviations; changes of identity.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... identity. 36.4304 Section 36.4304 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS... Deviations; changes of identity. A deviation of more than 5 percent between the estimates upon which a... change in the identity of the property upon which the original appraisal was based, will invalidate...

  9. 38 CFR 36.4304 - Deviations; changes of identity.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... identity. 36.4304 Section 36.4304 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS... Deviations; changes of identity. A deviation of more than 5 percent between the estimates upon which a... change in the identity of the property upon which the original appraisal was based, will invalidate...

  10. 21 CFR 211.100 - Written procedures; deviations.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 4 2014-04-01 2014-04-01 false Written procedures; deviations. 211.100 Section... Process Controls § 211.100 Written procedures; deviations. (a) There shall be written procedures for... in this subpart. These written procedures, including any changes, shall be drafted, reviewed,...

  11. Syntactic Deviations in the Novel "The Sound and the Fury"

    ERIC Educational Resources Information Center

    Alirezazadeh, Pooria; Talebinezhad, Mohammad Reza

    2014-01-01

    This article looks at William Faulkner's work "The Sound and the Fury." The goals are to investigate different types of syntactic deviations in the novel, and how these deviations helped the writer to create a literary work in the field of modernist literature and stream of consciousness. To this end, the theoretical framework for…

  12. 7 CFR 3015.3 - Conflicting policies and deviations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Conflicting policies and deviations. 3015.3 Section... Conflicting policies and deviations. (a) Statutory provisions. Federal statutes that apply to some USDA grant..., when permissible under existing laws. In those instances where a program receives an exception to...

  13. 40 CFR 63.1965 - What is a deviation?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... for Hazardous Air Pollutants: Municipal Solid Waste Landfills General and Continuing Compliance... landfill monitoring and SSM plan requirements, deviations include the items in paragraphs (a) through (c.... (c) A deviation occurs when a SSM plan is not developed or maintained on site....

  14. 10 CFR 1017.5 - Requesting a deviation.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 4 2013-01-01 2013-01-01 false Requesting a deviation. 1017.5 Section 1017.5 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) IDENTIFICATION AND PROTECTION OF UNCLASSIFIED CONTROLLED NUCLEAR... create a potential or real vulnerability); or (3) An exception (i.e., an approved deviation from...

  15. 9 CFR 318.308 - Deviations in processing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... deviation file. The establishment shall maintain full records regarding the handling of each deviation. Such records shall include, at a minimum, the appropriate processing and production records, a full description... establishment shall: (i) Immediately reprocess the product using the full process schedule; or (ii) Use...

  16. 9 CFR 318.308 - Deviations in processing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... deviation file. The establishment shall maintain full records regarding the handling of each deviation. Such records shall include, at a minimum, the appropriate processing and production records, a full description... establishment shall: (i) Immediately reprocess the product using the full process schedule; or (ii) Use...

  17. A standardized model for predicting flap failure using indocyanine green dye

    NASA Astrophysics Data System (ADS)

    Zimmermann, Terence M.; Moore, Lindsay S.; Warram, Jason M.; Greene, Benjamin J.; Nakhmani, Arie; Korb, Melissa L.; Rosenthal, Eben L.

    2016-03-01

    Techniques that provide a non-invasive method for evaluation of intraoperative skin flap perfusion are currently available but underutilized. We hypothesize that intraoperative vascular imaging can be used to reliably assess skin flap perfusion and elucidate areas of future necrosis by means of a standardized critical perfusion threshold. Five animal groups (negative controls, n=4; positive controls, n=5; chemotherapy group, n=5; radiation group, n=5; chemoradiation group, n=5) underwent pre-flap treatments two weeks prior to undergoing random pattern dorsal fasciocutaneous flaps with a length to width ratio of 2:1 (3 x 1.5 cm). Flap perfusion was assessed via laser-assisted indocyanine green dye angiography and compared to standard clinical assessment for predictive accuracy of flap necrosis. For estimating flap-failure, clinical prediction achieved a sensitivity of 79.3% and a specificity of 90.5%. When average flap perfusion was more than three standard deviations below the average flap perfusion for the negative control group at the time of the flap procedure (144.3+/-17.05 absolute perfusion units), laser-assisted indocyanine green dye angiography achieved a sensitivity of 81.1% and a specificity of 97.3%. When absolute perfusion units were seven standard deviations below the average flap perfusion for the negative control group, specificity of necrosis prediction was 100%. Quantitative absolute perfusion units can improve specificity for intraoperative prediction of viable tissue. Using this strategy, a positive predictive threshold of flap failure can be standardized for clinical use.

  18. Vibrational investigation on FT-IR and FT-Raman spectra, IR intensity, Raman activity, peak resemblance, ideal estimation, standard deviation of computed frequencies analyses and electronic structure on 3-methyl-1,2-butadiene using HF and DFT (LSDA/B3LYP/B3PW91) calculations

    NASA Astrophysics Data System (ADS)

    Ramalingam, S.; Jayaprakash, A.; Mohan, S.; Karabacak, M.

    2011-11-01

    FT-IR and FT-Raman (4000-100 cm -1) spectral measurements of 3-methyl-1,2-butadiene (3M12B) have been attempted in the present work. Ab-initio HF and DFT (LSDA/B3LYP/B3PW91) calculations have been performed giving energies, optimized structures, harmonic vibrational frequencies, IR intensities and Raman activities. Complete vibrational assignments on the observed spectra are made with vibrational frequencies obtained by HF and DFT (LSDA/B3LYP/B3PW91) at 6-31G(d,p) and 6-311G(d,p) basis sets. The results of the calculations have been used to simulate IR and Raman spectra for the molecule that showed good agreement with the observed spectra. The potential energy distribution (PED) corresponding to each of the observed frequencies are calculated which confirms the reliability and precision of the assignment and analysis of the vibrational fundamentals modes. The oscillation of vibrational frequencies of butadiene due to the couple of methyl group is also discussed. A study on the electronic properties such as HOMO and LUMO energies, were performed by time-dependent DFT (TD-DFT) approach. The calculated HOMO and LUMO energies show that charge transfer occurs within the molecule. The thermodynamic properties of the title compound at different temperatures reveal the correlations between standard heat capacities ( C) standard entropies ( S), and standard enthalpy changes ( H).

  19. [The crooked nose: correction of dorsal and caudal septal deviations].

    PubMed

    Foda, H M T

    2010-09-01

    The deviated nose represents a complex cosmetic and functional problem. Septal surgery plays a central role in the successful management of the externally deviated nose. This study included 800 patients seeking rhinoplasty to correct external nasal deviations; 71% of these suffered from variable degrees of nasal obstruction. Septal surgery was necessary in 736 (92%) patients, not only to improve breathing, but also to achieve a straight, symmetric external nose. A graduated surgical approach was adopted to allow correction of the dorsal and caudal deviations of the nasal septum without weakening its structural support to the nasal dorsum or nasal tip. The approach depended on full mobilization of deviated cartilage, followed by straightening of the cartilage and its fixation in the corrected position by using bony splinting grafts through an external rhinoplasty approach.

  20. Absolutely relative or relatively absolute: violations of value invariance in human decision making.

    PubMed

    Teodorescu, Andrei R; Moran, Rani; Usher, Marius

    2016-02-01

    Making decisions based on relative rather than absolute information processing is tied to choice optimality via the accumulation of evidence differences and to canonical neural processing via accumulation of evidence ratios. These theoretical frameworks predict invariance of decision latencies to absolute intensities that maintain differences and ratios, respectively. While information about the absolute values of the choice alternatives is not necessary for choosing the best alternative, it may nevertheless hold valuable information about the context of the decision. To test the sensitivity of human decision making to absolute values, we manipulated the intensities of brightness stimuli pairs while preserving either their differences or their ratios. Although asked to choose the brighter alternative relative to the other, participants responded faster to higher absolute values. Thus, our results provide empirical evidence for human sensitivity to task irrelevant absolute values indicating a hard-wired mechanism that precedes executive control. Computational investigations of several modelling architectures reveal two alternative accounts for this phenomenon, which combine absolute and relative processing. One account involves accumulation of differences with activation dependent processing noise and the other emerges from accumulation of absolute values subject to the temporal dynamics of lateral inhibition. The potential adaptive role of such choice mechanisms is discussed.

  1. A Preliminary Analysis on Empirical Attenuation of Absolute Velocity Response Spectra (1 to 10s) in Japan

    NASA Astrophysics Data System (ADS)

    Dhakal, Y. P.; Kunugi, T.; Suzuki, W.; Aoi, S.

    2013-12-01

    (T) = c+ aMw - log10R - bR +∑gS +hD where Y (T) is the 5% damped peak vector response in cm/s derived from two horizontal component records for a natural period T in second; in (2) S is a dummy variable which is one if a site is located inside a sedimentary basin, otherwise zero. In (3), D is depth to the top of layer having a particular S-wave velocity. We used the deep underground S-wave velocity model available from Japan Seismic Hazard Information Station (J-SHIS). In (5), sites are classified to various sedimentary basins. Analyses show that the standard deviations decrease in the order of the models listed and the all coefficients are significant. Interestingly, coefficients g are found to be different from basin to basin at most periods, and the depth to the top of layer having S-wave velocity of 1.7km/s gives the smallest standard deviation of 0.31 at T=4.4s in (5). This study shows the possibility of describing the observed peak absolute velocity response values by using simple model parameters like site location and sedimentary depth soon after the location and magnitude of an earthquake are known.

  2. Vertical deviations of the midplane of the Galaxy.

    NASA Astrophysics Data System (ADS)

    Malhotra, S.; Rhoads, J. E.

    Besides the integral sign warp in the outer Galaxy, the gas in the Milky Way shows small, but systematic deviations from a flat z = 0 plane both in the inner and the outer Galaxy. In the inner Galaxy, the tangent points have no distance ambiguity, so their distances, and hence midplane deviations, can be measured. From the tangent point analysis the authors find that the molecular and atomic gas layers deviate from the z = 0 plane with an amplitude of ≅50 pc. Whether these deviations are due to a small, smooth inner warp or are similar to the m = 10 mode corrugations found in the outer Galaxy (Kulkarni, Blitz & Heiles, 1982) can be checked by looking at the two-dimensional (in Galactic radius and azimuthal angle) structure of the z deviations. For the inner Galaxy, distance ambiguity at points other than the tangent points makes the interpretation difficult, but these hypotheses can be checked in a limited way. Magnetic instabilities can cause vertical deviations of the gas, but if stars share the same deviations the origin has to be gravitational.

  3. Comparative vs. Absolute Judgments of Trait Desirability

    ERIC Educational Resources Information Center

    Hofstee, Willem K. B.

    1970-01-01

    Reversals of trait desirability are studied. Terms indicating conservativw behavior appeared to be judged relatively desirable in comparative judgement, while traits indicating dynamic and expansive behavior benefited from absolute judgement. The reversal effect was shown to be a general one, i.e. reversals were not dependent upon the specific…

  4. New Techniques for Absolute Gravity Measurements.

    DTIC Science & Technology

    1983-01-07

    Hammond, J.A. (1978) Bollettino Di Geofisica Teorica ed Applicata Vol. XX. 8. Hammond, J. A., and Iliff, R. L. (1979) The AFGL absolute gravity system...International Gravimetric Bureau, No. L:I-43. 7. Hammond. J.A. (1978) Bollettino Di Geofisica Teorica ed Applicata Vol. XX. 8. Hammond, J.A., and

  5. An Absolute Electrometer for the Physics Laboratory

    ERIC Educational Resources Information Center

    Straulino, S.; Cartacci, A.

    2009-01-01

    A low-cost, easy-to-use absolute electrometer is presented: two thin metallic plates and an electronic balance, usually available in a laboratory, are used. We report on the very good performance of the device that allows precise measurements of the force acting between two charged plates. (Contains 5 footnotes, 2 tables, and 6 figures.)

  6. Stimulus Probability Effects in Absolute Identification

    ERIC Educational Resources Information Center

    Kent, Christopher; Lamberts, Koen

    2016-01-01

    This study investigated the effect of stimulus presentation probability on accuracy and response times in an absolute identification task. Three schedules of presentation were used to investigate the interaction between presentation probability and stimulus position within the set. Data from individual participants indicated strong effects of…

  7. Absolute Positioning Using the Global Positioning System

    DTIC Science & Technology

    1994-04-01

    Global Positioning System ( GPS ) has becom a useful tool In providing relativ survey...Includes the development of a low cost navigator for wheeled vehicles. ABSTRACT The Global Positioning System ( GPS ) has become a useful tool In providing...technique of absolute or point positioning involves the use of a single Global Positioning System ( GPS ) receiver to determine the three-dimenslonal

  8. Selected Reaction Monitoring Mass Spectrometry for Absolute Protein Quantification.

    PubMed

    Manes, Nathan P; Mann, Jessica M; Nita-Lazar, Aleksandra

    2015-08-17

    Absolute quantification of target proteins within complex biological samples is critical to a wide range of research and clinical applications. This protocol provides step-by-step instructions for the development and application of quantitative assays using selected reaction monitoring (SRM) mass spectrometry (MS). First, likely quantotypic target peptides are identified based on numerous criteria. This includes identifying proteotypic peptides, avoiding sites of posttranslational modification, and analyzing the uniqueness of the target peptide to the target protein. Next, crude external peptide standards are synthesized and used to develop SRM assays, and the resulting assays are used to perform qualitative analyses of the biological samples. Finally, purified, quantified, heavy isotope labeled internal peptide standards are prepared and used to perform isotope dilution series SRM assays. Analysis of all of the resulting MS data is presented. This protocol was used to accurately assay the absolute abundance of proteins of the chemotaxis signaling pathway within RAW 264.7 cells (a mouse monocyte/macrophage cell line). The quantification of Gi2 (a heterotrimeric G-protein α-subunit) is described in detail.

  9. Reflected beam's direction deviation induced by the corner cube retroreflector

    NASA Astrophysics Data System (ADS)

    Huang, Jian; Xian, Hao; Jang, WenHan

    2008-12-01

    The direction deviation of the reflected beam induced by the corner cube retroreflector (CCR) is respectively discussed by geometrical optics approach and the principle of physical optics in this paper. A mathematical model was built to calculate the beam's aberration due to the fabrication errors of the CCR. It can be concluded that the centroid direction error of far field spot is much more appropriate to describe the reflection beam's direction deviation for a broad incident beam, and the beam with even intensity distribution should be used to reduce its direction deviation.

  10. Fluctuations and large deviations in non-equilibrium systems

    NASA Astrophysics Data System (ADS)

    Derrida, B.

    2005-05-01

    For systems in contact with two reservoirs at different densities or with two thermostats at different temperatures, the large deviation function of the density gives a possible way of extending the notion of free energy to non-equilibrium systems. This large deviation function of the density can be calculated explicitly for exclusion models in one dimension with open boundary conditions. For these models, one can also obtain the distribution of the current of particles flowing through the system and the results lead to a simple conjecture for the large deviation function of the current of more general diffusive systems.

  11. Lunar eclipse photometry: absolute luminance measurements and modeling.

    PubMed

    Hernitschek, Nina; Schmidt, Elmar; Vollmer, Michael

    2008-12-01

    The Moon's time-dependent luminance was determined during the 9 February 1990 and 3 March 2007 total lunar eclipses by using calibrated, industry standard photometers. After the results were corrected to unit air mass and to standard distances for both Moon and Sun, an absolute calibration was accomplished by using the Sun's known luminance and a pre-eclipse lunar albedo of approximately 13.5%. The measured minimum level of brightness in the total phase of both eclipses was relatively high, namely -3.32 m(vis) and -1.7 m(vis), which hints at the absence of pronounced stratospheric aerosol. The light curves were modeled in such a way as to let the Moon move through an artificial Earth shadow composed of a multitude of disk and ring zones, containing a relative luminance data set from an atmospheric radiative transfer calculation.

  12. Velocity Structure Determination Through Seismic Waveform Modeling and Time Deviations

    NASA Astrophysics Data System (ADS)

    Savage, B.; Zhu, L.; Tan, Y.; Helmberger, D. V.

    2001-12-01

    Through the use of seismic waveforms recorded by TriNet, a dataset of earthquake focal mechanisms and deviations (time shifts) relative to a standard model facilitates the investigation of the crust and uppermost mantle of southern California. The CAP method of focal mechanism determination, in use by TriNet on a routine basis, provides time shifts for surface waves and Pnl arrivals independently relative to the reference model. These shifts serve as initial data for calibration of local and regional seismic paths. Time shifts from the CAP method are derived by splitting the Pnl section of the waveform, the first arriving Pn to just before the arrival of the S wave, from the much slower surface waves then cross-correlating the data with synthetic waveforms computed from a standard model. Surface waves interact with the entire crust, but the upper crust causes the greatest effect. Whereas, Pnl arrivals sample the deeper crust, upper mantle, and source region. This natural division separates the upper from lower crust for regional calibration and structural modeling and allows 3-D velocity maps to be created using the resulting time shifts. Further examination of Pnl and other arrivals which interact with the Moho illuminate the complex nature of this boundary. Initial attempts at using the first 10 seconds of the Pnl section to determine upper most mantle structure have proven insightful. Two large earthquakes north of southern California in Nevada and Mammoth Lakes, CA allow the creation of record sections from 200 to 600 km. As the paths swing from east to west across southern California, simple 1-D models turn into complex structure, dramatically changing the waveform character. Using finite difference models to explain the structure, we determine that a low velocity zone is present at the base of the crust and extends to 100 km in depth. Velocity variations of 5 percent of the mantle in combination with steeply sloping edges produces complex waveform variations

  13. Deviation of the statistical fluctuation in heterogeneous anomalous diffusion

    NASA Astrophysics Data System (ADS)

    Itto, Yuichi

    2016-11-01

    The exponent of anomalous diffusion of virus in cytoplasm of a living cell is experimentally known to fluctuate depending on localized areas of the cytoplasm, indicating heterogeneity of diffusion. In a recent paper (Itto, 2012), a maximum-entropy-principle approach has been developed in order to propose an Ansatz for the statistical distribution of such exponent fluctuations. Based on this approach, here the deviation of the statistical distribution of the fluctuations from the proposed one is studied from the viewpoint of Einstein's theory of fluctuations (of the thermodynamic quantities). This may present a step toward understanding the statistical property of the deviation. It is shown in a certain class of small deviations that the deviation obeys the multivariate Gaussian distribution.

  14. Large Deviations and a Fluctuation Symmetry for Chaotic Homeomorphisms

    NASA Astrophysics Data System (ADS)

    Maes, Christian; Verbitskiy, Evgeny

    We consider expansive homeomorphisms with the specification property. We give a new simple proof of a large deviation principle for Gibbs measures corresponding to a regular potential and we establish a general symmetry of the rate function for the large deviations of the antisymmetric part, under time-reversal, of the potential. This generalizes the Gallavotti-Cohen fluctuation theorem to a larger class of chaotic systems.

  15. Perception of midline deviations in smile esthetics by laypersons

    PubMed Central

    Ferreira, Jamille Barros; da Silva, Licínio Esmeraldo; Caetano, Márcia Tereza de Oliveira; da Motta, Andrea Fonseca Jardim; Cury-Saramago, Adriana de Alcantara; Mucha, José Nelson

    2016-01-01

    ABSTRACT Objective: To evaluate the esthetic perception of upper dental midline deviation by laypersons and if adjacent structures influence their judgment. Methods: An album with 12 randomly distributed frontal view photographs of the smile of a woman with the midline digitally deviated was evaluated by 95 laypersons. The frontal view smiling photograph was modified to create from 1 mm to 5 mm deviations in the upper midline to the left side. The photographs were cropped in two different manners and divided into two groups of six photographs each: group LCN included the lips, chin, and two-thirds of the nose, and group L included the lips only. The laypersons performed the rate of each smile using a visual analog scale (VAS). Wilcoxon test, Student’s t-test and Mann-Whitney test were applied, adopting a 5% level of significance. Results: Laypersons were able to perceive midline deviations starting at 1 mm. Statistically significant results (p< 0.05) were found for all multiple comparisons of the values in photographs of group LCN and for almost all comparisons in photographs of group L. Comparisons between the photographs of groups LCN and L showed statistically significant values (p< 0.05) when the deviation was 1 mm. Conclusions: Laypersons were able to perceive the upper dental midline deviations of 1 mm, and above when the adjacent structures of the smiles were included. Deviations of 2 mm and above when the lips only were included. The visualization of structures adjacent to the smile demonstrated influence on the perception of midline deviation. PMID:28125140

  16. Computerized inspection of real surfaces and minimization of their deviations

    NASA Technical Reports Server (NTRS)

    Litvin, Faydor L.; Zhang, Y.; Kuan, Chihping; Handschuh, R. F.

    1991-01-01

    A method is developed for the minimization of gear tooth surface deviations between theoretical and real surfaces for the improvement of precision of surface manufacture. Coordinate measurement machinery is used to determine a grid of surface coordinates. Theoretical calculations are made for the grid points. A least-square method is used to minimize the deviations between real and theoretical surfaces by altering the manufacturing machine-tool settings. An example is given for a hypoid gear.

  17. Nasal Septal Deviations: A Systematic Review of Classification Systems.

    PubMed

    Teixeira, Jeffrey; Certal, Victor; Chang, Edward T; Camacho, Macario

    2016-01-01

    Objective. To systematically review the international literature for internal nasal septal deviation classification systems and summarize them for clinical and research purposes. Data Sources. Four databases (including PubMed/MEDLINE) were systematically searched through December 16, 2015. Methods. Systematic review, adhering to PRISMA. Results. After removal of duplicates, this study screened 952 articles for relevance. A final comprehensive review of 50 articles identified that 15 of these articles met the eligibility criteria. The classification systems defined in these articles included C-shaped, S-shaped, reverse C-shaped, and reverse S-shaped descriptions of the septal deviation in both the cephalocaudal and anteroposterior dimensions. Additional studies reported use of computed tomography and categorized deviation based on predefined locations. Three studies graded the severity of septal deviations based on the amount of deflection. The systems defined in the literature also included an evaluation of nasal septal spurs and perforations. Conclusion. This systematic review ascertained that the majority of the currently published classification systems for internal nasal septal deviations can be summarized by C-shaped or reverse C-shaped, as well as S-shaped or reverse S-shaped deviations in the anteroposterior and cephalocaudal dimensions. For imaging studies, predefined points have been defined along the septum. Common terminology can facilitate future research.

  18. The reaction H + C4H2 - Absolute rate constant measurement and implication for atmospheric modeling of Titan

    NASA Technical Reports Server (NTRS)

    Nava, D. F.; Mitchell, M. B.; Stief, L. J.

    1986-01-01

    The absolute rate constant for the reaction H + C4H2 has been measured over the temperature (T) interval 210-423 K, using the technique of flash photolysis-resonance fluorescence. At each of the five temperatures employed, the results were independent of variations in C4H2 concentration, total pressure of Ar or N2, and flash intensity (i.e., the initial H concentration). The rate constant, k, was found to be equal to 1.39 x 10 to the -10th exp (-1184/T) cu cm/s, with an error of one standard deviation. The Arrhenius parameters at the high pressure limit determined here for the H + C4H2 reaction are consistent with those for the corresponding reactions of H with C2H2 and C3H4. Implications of the kinetic carbon chemistry results, particularly those at low temperature, are considered for models of the atmospheric carbon chemistry of Titan. The rate of this reaction, relative to that of the analogous, but slower, reaction of H + C2H2, appears to make H + C4H2 a very feasible reaction pathway for effective conversion of H atoms to molecular hydrogen in the stratosphere of Titan.

  19. Absolute Absorption Intensities in the Fundamental nu2 and nu5 Bands of 12CH3F.

    PubMed

    Lepère; Blanquet; Walrand; Tarrago

    1998-06-01

    The absolute strengths of 93 lines belonging to the nu2 and nu5 bands of methyl fluoride were measured in the range of 1416-1503 cm-1 using a tunable diode-laser (TDL) spectrometer. These experimental line intensities were obtained from the equivalent width method. The intensities were analyzed within a dyad system, required to account properly for the strong Coriolis coupling between nu2 and nu5. The fit to the experimental data led to the determination of the dipole moment derivatives partial differentialµ/ partial differentialq2 and partial differentialµ/ partial differentialq5, as well as the first-order Herman-Wallis correction in K to partial differentialµ/ partial differentialq5. The intensities were reproduced with an overall standard deviation of 1.44%, to be compared with a mean experimental uncertainty equal to 1.58%. The values derived for the vibrational band strengths of nu2 and nu5 are 2.124 (18) cm-2.atm-1 and 36.96 cm-2.atm-1 at 296 K, respectively. Copyright 1998 Academic Press.

  20. The reaction H + C4H2 - Absolute rate constant measurement and implication for atmospheric modeling of Titan

    NASA Astrophysics Data System (ADS)

    Nava, D. F.; Mitchell, M. B.; Stief, L. J.

    1986-04-01

    The absolute rate constant for the reaction H + C4H2 has been measured over the temperature (T) interval 210-423 K, using the technique of flash photolysis-resonance fluorescence. At each of the five temperatures employed, the results were independent of variations in C4H2 concentration, total pressure of Ar or N2, and flash intensity (i.e., the initial H concentration). The rate constant, k, was found to be equal to 1.39 x 10 to the -10th exp (-1184/T) cu cm/s, with an error of one standard deviation. The Arrhenius parameters at the high pressure limit determined here for the H + C4H2 reaction are consistent with those for the corresponding reactions of H with C2H2 and C3H4. Implications of the kinetic carbon chemistry results, particularly those at low temperature, are considered for models of the atmospheric carbon chemistry of Titan. The rate of this reaction, relative to that of the analogous, but slower, reaction of H + C2H2, appears to make H + C4H2 a very feasible reaction pathway for effective conversion of H atoms to molecular hydrogen in the stratosphere of Titan.

  1. Consistent thermostatistics forbids negative absolute temperatures

    NASA Astrophysics Data System (ADS)

    Dunkel, Jörn; Hilbert, Stefan

    2014-01-01

    Over the past 60 years, a considerable number of theories and experiments have claimed the existence of negative absolute temperature in spin systems and ultracold quantum gases. This has led to speculation that ultracold gases may be dark-energy analogues and also suggests the feasibility of heat engines with efficiencies larger than one. Here, we prove that all previous negative temperature claims and their implications are invalid as they arise from the use of an entropy definition that is inconsistent both mathematically and thermodynamically. We show that the underlying conceptual deficiencies can be overcome if one adopts a microcanonical entropy functional originally derived by Gibbs. The resulting thermodynamic framework is self-consistent and implies that absolute temperature remains positive even for systems with a bounded spectrum. In addition, we propose a minimal quantum thermometer that can be implemented with available experimental techniques.

  2. Absolute measurement of length with nanometric resolution

    NASA Astrophysics Data System (ADS)

    Apostol, D.; Garoi, F.; Timcu, A.; Damian, V.; Logofatu, P. C.; Nascov, V.

    2005-08-01

    Laser interferometer displacement measuring transducers have a well-defined traceability route to the definition of the meter. The laser interferometer is de-facto length scale for applications in micro and nano technologies. However their physical unit -half lambda is too large for nanometric resolution. Fringe interpolation-usual technique to improve the resolution-lack of reproducibility could be avoided using the principles of absolute distance measurement. Absolute distance refers to the use of interferometric techniques for determining the position of an object without the necessity of measuring continuous displacements between points. The interference pattern as produced by the interference of two point-like coherent sources is fitted to a geometric model so as to determine the longitudinal location of the target by minimizing least square errors. The longitudinal coordinate of the target was measured with accuracy better than 1 nm, for a target position range of 0.4μm.

  3. Asteroid absolute magnitudes and slope parameters

    NASA Technical Reports Server (NTRS)

    Tedesco, Edward F.

    1991-01-01

    A new listing of absolute magnitudes (H) and slope parameters (G) has been created and published in the Minor Planet Circulars; this same listing will appear in the 1992 Ephemerides of Minor Planets. Unlike previous listings, the values of the current list were derived from fits of data at the V band. All observations were reduced in the same fashion using, where appropriate, a single basis default value of 0.15 for the slope parameter. Distances and phase angles were computed for each observation. The data for 113 asteroids was of sufficiently high quality to permit derivation of their H and G. These improved absolute magnitudes and slope parameters will be used to deduce the most reliable bias-corrected asteroid size-frequency distribution yet made.

  4. Computer processing of spectrograms for absolute intensities.

    PubMed

    Guttman, A; Golden, J; Galbraith, H J

    1967-09-01

    A computer program was developed to process photographically recorded spectra for absolute intensity. Test and calibration films are subjected to densitometric scans that provide digitally recorded densities on magnetic tapes. The nonlinear calibration data are fitted by least-squares cubic polynomials to yield a good approximation to the monochromatic H&D curves for commonly used emulsions (2475 recording film, Royal-X, Tri-X, 4-X). Several test cases were made. Results of these cases show that the machine processed absolute intensities are accurate to within 15%o. Arbitrarily raising the sensitivity threshold by 0.1 density units above gross fog yields cubic polynomial fits to the H&D curves that are radiometrically accurate within 10%. In addition, curves of gamma vs wavelength for 2475, Tri-X, and 4-X emulsions were made. These data show slight evidence of the photographic Purkinje effect in the 2475 emulsion.

  5. An absolute measure for a key currency

    NASA Astrophysics Data System (ADS)

    Oya, Shunsuke; Aihara, Kazuyuki; Hirata, Yoshito

    It is generally considered that the US dollar and the euro are the key currencies in the world and in Europe, respectively. However, there is no absolute general measure for a key currency. Here, we investigate the 24-hour periodicity of foreign exchange markets using a recurrence plot, and define an absolute measure for a key currency based on the strength of the periodicity. Moreover, we analyze the time evolution of this measure. The results show that the credibility of the US dollar has not decreased significantly since the Lehman shock, when the Lehman Brothers bankrupted and influenced the economic markets, and has increased even relatively better than that of the euro and that of the Japanese yen.

  6. Probing absolute spin polarization at the nanoscale.

    PubMed

    Eltschka, Matthias; Jäck, Berthold; Assig, Maximilian; Kondrashov, Oleg V; Skvortsov, Mikhail A; Etzkorn, Markus; Ast, Christian R; Kern, Klaus

    2014-12-10

    Probing absolute values of spin polarization at the nanoscale offers insight into the fundamental mechanisms of spin-dependent transport. Employing the Zeeman splitting in superconducting tips (Meservey-Tedrow-Fulde effect), we introduce a novel spin-polarized scanning tunneling microscopy that combines the probing capability of the absolute values of spin polarization with precise control at the atomic scale. We utilize our novel approach to measure the locally resolved spin polarization of magnetic Co nanoislands on Cu(111). We find that the spin polarization is enhanced by 65% when increasing the width of the tunnel barrier by only 2.3 Å due to the different decay of the electron orbitals into vacuum.

  7. Absolute and relative dosimetry for ELIMED

    NASA Astrophysics Data System (ADS)

    Cirrone, G. A. P.; Cuttone, G.; Candiano, G.; Carpinelli, M.; Leonora, E.; Lo Presti, D.; Musumarra, A.; Pisciotta, P.; Raffaele, L.; Randazzo, N.; Romano, F.; Schillaci, F.; Scuderi, V.; Tramontana, A.; Cirio, R.; Marchetto, F.; Sacchi, R.; Giordanengo, S.; Monaco, V.

    2013-07-01

    The definition of detectors, methods and procedures for the absolute and relative dosimetry of laser-driven proton beams is a crucial step toward the clinical use of this new kind of beams. Hence, one of the ELIMED task, will be the definition of procedures aiming to obtain an absolute dose measure at the end of the transport beamline with an accuracy as close as possible to the one required for clinical applications (i.e. of the order of 5% or less). Relative dosimetry procedures must be established, as well: they are necessary in order to determine and verify the beam dose distributions and to monitor the beam fluence and the energetic spectra during irradiations. Radiochromic films, CR39, Faraday Cup, Secondary Emission Monitor (SEM) and transmission ionization chamber will be considered, designed and studied in order to perform a fully dosimetric characterization of the ELIMED proton beam.

  8. Silicon Absolute X-Ray Detectors

    SciTech Connect

    Seely, John F.; Korde, Raj; Sprunck, Jacob; Medjoubi, Kadda; Hustache, Stephanie

    2010-06-23

    The responsivity of silicon photodiodes having no loss in the entrance window, measured using synchrotron radiation in the 1.75 to 60 keV range, was compared to the responsivity calculated using the silicon thickness measured using near-infrared light. The measured and calculated responsivities agree with an average difference of 1.3%. This enables their use as absolute x-ray detectors.

  9. Negative absolute temperature for mobile particles

    NASA Astrophysics Data System (ADS)

    Braun, Simon; Ronzheimer, Philipp; Schreiber, Michael; Hodgman, Sean; Bloch, Immanuel; Schneider, Ulrich

    2013-05-01

    Absolute temperature is usually bound to be strictly positive. However, negative absolute temperature states, where the occupation probability of states increases with their energy, are possible in systems with an upper energy bound. So far, such states have only been demonstrated in localized spin systems with finite, discrete spectra. We realized a negative absolute temperature state for motional degrees of freedom with ultracold bosonic 39K atoms in an optical lattice, by implementing the attractive Bose-Hubbard Hamiltonian. This new state strikingly revealed itself by a quasimomentum distribution that is peaked at maximum kinetic energy. The measured kinetic energy distribution and the extracted negative temperature indicate that the ensemble is close to degeneracy, with coherence over several lattice sites. The state is as stable as a corresponding positive temperature state: The negative temperature stabilizes the system against mean-field collapse driven by negative pressure. Negative temperatures open up new parameter regimes for cold atoms, enabling fundamentally new many-body states. Additionally, they give rise to several counterintuitive effects such as heat engines with above unity efficiency.

  10. Measurement of absolute gravity acceleration in Firenze

    NASA Astrophysics Data System (ADS)

    de Angelis, M.; Greco, F.; Pistorio, A.; Poli, N.; Prevedelli, M.; Saccorotti, G.; Sorrentino, F.; Tino, G. M.

    2011-01-01

    This paper reports the results from the accurate measurement of the acceleration of gravity g taken at two separate premises in the Polo Scientifico of the University of Firenze (Italy). In these laboratories, two separate experiments aiming at measuring the Newtonian constant and testing the Newtonian law at short distances are in progress. Both experiments require an independent knowledge on the local value of g. The only available datum, pertaining to the italian zero-order gravity network, was taken more than 20 years ago at a distance of more than 60 km from the study site. Gravity measurements were conducted using an FG5 absolute gravimeter, and accompanied by seismic recordings for evaluating the noise condition at the site. The absolute accelerations of gravity at the two laboratories are (980 492 160.6 ± 4.0) μGal and (980 492 048.3 ± 3.0) μGal for the European Laboratory for Non-Linear Spectroscopy (LENS) and Dipartimento di Fisica e Astronomia, respectively. Other than for the two referenced experiments, the data here presented will serve as a benchmark for any future study requiring an accurate knowledge of the absolute value of the acceleration of gravity in the study region.

  11. Determination of the absolute configuration of a novel dipeptide isostere.

    PubMed

    Lynch, V M; Austin, R E; Martin, S F; George, T

    1991-06-15

    (1R-[1 alpha(1R*,2R*,3S*),2 beta,5 alpha])-2-(4-Morpholinocarbonyl)- 3-phenylcyclopropane 2-(1-methyl-ethyl)-5-methylcyclohexyl ester, C25H35NO4, Mr = 413 x 56, orthorhombic, P2(1)2(1)2(1), a = 9 x 359 (2), b = 10 x 1172 (14), c = 24 x 710 (4) A, V = 2339 x 8 (6) A3, Z = 4, Dx = 1 x 17 g cm-3, mu = 0 x 7332 cm-1, Mo K alpha radiation, lambda = 0 x 7107 A, F(000) = 896, T = 198 K, R = 0 x 0475 for 2460 reflections [Fo greater than or equal to 4 sigma(Fo)]. The assignment of the absolute configuration was based on internal comparison to the (-)-menthol moiety. The morpholenyl and cyclohexyl rings are in the chair conformation. The amide group is essentially planar [max. deviation 0.025 (2) A for N19] resulting in a close non-bonded contact between the amide oxygen, O18, and H24a of 2 x 24 (4) A.

  12. TU-A-12A-09: Absolute Blood Flow Measurement in a Cardiac Phantom Using Low Dose CT

    SciTech Connect

    Ziemer, B; Hubbard, L; Lipinski, J; Molloi, S

    2014-06-15

    Purpose: To investigate a first pass analysis technique to measure absolute flow from low dose CT images in a cardiac phantom. This technique can be combined with a myocardial mass assignment to yield absolute perfusion using only two volume scans and reduce the radiation dose to the patient. Methods: A four-chamber cardiac phantom and perfusion chamber were constructed from poly-acrylic and connected with tubing to approximate anatomical features. The system was connected to a pulsatile pump, input/output reservoirs and power contrast injector. Flow was varied in the range of 1-2.67 mL/s with the pump operating at 60 beats/min. The system was imaged once a second for 14 seconds with a 320-row scanner (Toshiba Medical Systems) using a contrast-enhanced, prospective-gated cardiac perfusion protocol. Flow was calculated by the following steps: subsequent images of the perfusion volume were subtracted to find the contrast entering the volume; this was normalized by an upstream, known volume region to convert Hounsfield (HU) values to concentration; this was divided by the subtracted images time difference. The technique requires a relatively stable input contrast concentration and no contrast can leave the perfusion volume before the flow measurement is completed. Results: The flow calculated from the images showed an excellent correlation with the known rates. The data was fit to a linear function with slope 1.03, intercept 0.02 and an R{sup 2} value of 0.99. The average root mean square (RMS) error was 0.15 mL/s and the average standard deviation was 0.14 mL/s. The flow rate was stable within 7.7% across the full scan and served to validate model assumptions. Conclusion: Accurate, absolute flow rates were measured from CT images using a conservation of mass model. Measurements can be made using two volume scans which can substantially reduce the radiation dose compared with current dynamic perfusion techniques.

  13. Thorough subcells diagnosis in a multi-junction solar cell via absolute electroluminescence-efficiency measurements.

    PubMed

    Chen, Shaoqiang; Zhu, Lin; Yoshita, Masahiro; Mochizuki, Toshimitsu; Kim, Changsu; Akiyama, Hidefumi; Imaizumi, Mitsuru; Kanemitsu, Yoshihiko

    2015-01-16

    World-wide studies on multi-junction (tandem) solar cells have led to record-breaking improvements in conversion efficiencies year after year. To obtain detailed and proper feedback for solar-cell design and fabrication, it is necessary to establish standard methods for diagnosing subcells in fabricated tandem devices. Here, we propose a potential standard method to quantify the detailed subcell properties of multi-junction solar cells based on absolute measurements of electroluminescence (EL) external quantum efficiency in addition to the conventional solar-cell external-quantum-efficiency measurements. We demonstrate that the absolute-EL-quantum-efficiency measurements provide I-V relations of individual subcells without the need for referencing measured I-V data, which is in stark contrast to previous works. Moreover, our measurements quantify the absolute rates of junction loss, non-radiative loss, radiative loss, and luminescence coupling in the subcells, which constitute the "balance sheets" of tandem solar cells.

  14. Application of Allan Deviation to Assessing Uncertainties of Continuous-measurement Instruments, and Optimizing Calibration Schemes

    NASA Astrophysics Data System (ADS)

    Jacobson, Gloria; Rella, Chris; Farinas, Alejandro

    2014-05-01

    Technological advancement of instrumentation in atmospheric and other geoscience disciplines over the past decade has lead to a shift from discrete sample analysis to continuous, in-situ monitoring. Standard error analysis used for discrete measurements is not sufficient to assess and compare the error contribution of noise and drift from continuous-measurement instruments, and a different statistical analysis approach should be applied. The Allan standard deviation analysis technique developed for atomic clock stability assessment by David W. Allan [1] can be effectively and gainfully applied to continuous measurement instruments. As an example, P. Werle et al has applied these techniques to look at signal averaging for atmospheric monitoring by Tunable Diode-Laser Absorption Spectroscopy (TDLAS) [2]. This presentation will build on, and translate prior foundational publications to provide contextual definitions and guidelines for the practical application of this analysis technique to continuous scientific measurements. The specific example of a Picarro G2401 Cavity Ringdown Spectroscopy (CRDS) analyzer used for continuous, atmospheric monitoring of CO2, CH4 and CO will be used to define the basics features the Allan deviation, assess factors affecting the analysis, and explore the time-series to Allan deviation plot translation for different types of instrument noise (white noise, linear drift, and interpolated data). In addition, the useful application of using an Allan deviation to optimize and predict the performance of different calibration schemes will be presented. Even though this presentation will use the specific example of the Picarro G2401 CRDS Analyzer for atmospheric monitoring, the objective is to present the information such that it can be successfully applied to other instrument sets and disciplines. [1] D.W. Allan, "Statistics of Atomic Frequency Standards," Proc, IEEE, vol. 54, pp 221-230, Feb 1966 [2] P. Werle, R. Miicke, F. Slemr, "The Limits

  15. Deviations from Newton's law in supersymmetric large extra dimensions

    NASA Astrophysics Data System (ADS)

    Callin, P.; Burgess, C. P.

    2006-09-01

    Deviations from Newton's inverse-squared law at the micron length scale are smoking-gun signals for models containing supersymmetric large extra dimensions (SLEDs), which have been proposed as approaches for resolving the cosmological constant problem. Just like their non-supersymmetric counterparts, SLED models predict gravity to deviate from the inverse-square law because of the advent of new dimensions at sub-millimeter scales. However SLED models differ from their non-supersymmetric counterparts in three important ways: (i) the size of the extra dimensions is fixed by the observed value of the dark energy density, making it impossible to shorten the range over which new deviations from Newton's law must be seen; (ii) supersymmetry predicts there to be more fields in the extra dimensions than just gravity, implying different types of couplings to matter and the possibility of repulsive as well as attractive interactions; and (iii) the same mechanism which is purported to keep the cosmological constant naturally small also keeps the extra-dimensional moduli effectively massless, leading to deviations from general relativity in the far infrared of the scalar-tensor form. We here explore the deviations from Newton's law which are predicted over micron distances, and show the ways in which they differ and resemble those in the non-supersymmetric case.

  16. Cosolvency and deviations from log-linear solubilization.

    PubMed

    Rubino, J T; Yalkowsky, S H

    1987-06-01

    The solubilities of three nonpolar drugs, phenytoin, diazepam, and benzocaine, have been measured in 14 cosolvent-water binary mixtures. The observed solubilities were examined for deviations from solubilities calculated by the equation log Sm = f log Sc + (1 - f) log Sw, where Sm is the solubility of the drug in the cosolvent-water mixture, Sc is the solubility of the drug in neat cosolvent, f is the volume fraction of cosolvent, and Sw is the solubility of the drug in water. When presented graphically, the patterns of the deviations were similar for all three drugs in mixtures of amphiprotic cosolvents (glycols, polyols, and alcohols) and water as well as nonpolar, aprotic cosolvents (dioxane, triglyme, dimethyl isosorbide) and water. The deviations were positive for phenytoin and benzocaine but negative for diazepam in mixtures of dipolar, aprotic cosolvents (dimethylsulfoxide, dimethylformamide, and dimethylacetamide) and water. The source of the deviations could not consistently be attributed to physical properties of the cosolvent-water mixtures or to alterations in the solute crystal. Similarities between the results of this study and those of previous investigations suggest that changes in the structure of the solvent play a role in the deviations from the expected solubilities.

  17. Interferometric determination of the topographies of absolute sphere radii using the sphere interferometer of PTB

    NASA Astrophysics Data System (ADS)

    Bartl, Guido; Krystek, Michael; Nicolaus, Arnold; Giardini, Walter

    2010-11-01

    This paper presents a method to reconstruct the absolute shape of a sphere—i.e. a topography of radii—using the sphere interferometer of PTB in combination with a stitching approach. The method allows for the reconstruction of absolute radii instead of the relative shape deviations which result from conventional sphericity measurements. The sphere interferometer was developed for the volume determination of spherical material measures—in particular the spheres of the Avogadro project—by precise diameter measurements with an uncertainty of 1 nm or less. In the scope of the present work a procedure has been implemented that extends the applicability of the interferometer to fields where not the volume or diameter but the direction-dependent radii are of interest. The results of the reconstruction were compared quantitatively to the independent results of sphericity measurements from CSIRO.

  18. Absolute rotation detection by Coriolis force measurement using optomechanics

    NASA Astrophysics Data System (ADS)

    Davuluri, Sankar; Li, Yong

    2016-10-01

    In this article, we present an application of the optomechanical cavities for absolute rotation detection. Two optomechanical cavities, one in each arm, are placed in a Michelson interferometer. The interferometer is placed on a rotating table and is moved with a uniform velocity of \\dot{\\bar{y}} with respect to the rotating table. The Coriolis force acting on the interferometer changes the length of the optomechanical cavity in one arm, while the length of the optomechanical cavity in the other arm is not changed. The phase shift corresponding to the change in the optomechanical cavity length is measured at the interferometer output to estimate the angular velocity of the absolute rotation. An analytic expression for the minimum detectable rotation rate corresponding to the standard quantum limit of measurable Coriolis force in the interferometer is derived. Squeezing technique is discussed to improve the rotation detection sensitivity by a factor of \\sqrt{{γ }m/{ω }m} at 0 K temperature, where {γ }m and {ω }m are the damping rate and angular frequency of the mechanical oscillator. The temperature dependence of the rotation detection sensitivity is studied.

  19. Mean Deviation of Inter-rater Scoring (MDIS): a simple tool for introducing conformity into groups of clinical investigators.

    PubMed

    Bourin, Michel; Deplanque, Dominique; Zins-Ritter, Marcel

    2004-07-01

    In spite of considerable progress over the past decade, training investigators for inter-rater reliability for clinical trials remains a major problem. The aim of the present study was to promote a new tool to increase data homogeneity by introducing conformity into groups of clinical investigators. The investigators scoring grid we are proposing-the Mean Deviation of Inter-rater Scoring (MDIS)-involves the calculation of the score deviation for each investigator relative to the median score of an expert group who had evaluated the same videotape-recorded clinical case. Whatever the scale, the score deviation is calculated as the absolute deviation value from the median score obtained by the experts for each item. The MDIS value is then evaluated from all the scores given by an investigator by dividing the total sum of the previously defined values by the number of items of the scale. Some examples from practice are given using several rating scales: (i) Hamilton Anxiety Rating Scale; (ii) Hamilton Depression Rating Scale; (iii) Montgomery Asberg Depression Rating Scale; and (iv) Positive And Negative Symptoms Scale. Finally, such a method could also be employed by experts to evaluate the quality of videotape-recorded clinical cases used in clinical trials, as well as by teachers to evaluate initial or continuous medical training.

  20. Analytical Ferrography Standardization.

    DTIC Science & Technology

    1982-01-01

    normalized density readings versus slide position * Lease Squares Line: Y = ax + b * Mean Value of Density: YBAR * Standard Deviation of Density Distribution...11 =ZU U) y U)U 0 z w) LU Rip > -(0> > < cn z -U cc L c 0D CD Cl)>> >< > = 0 0 facilities, as illustrated in Figure 5. Upon receipt of the sample set...the standard deviation of the y population for a given x. The definition is: n-2 where Yi = actual values of y yic = values of y computed from the

  1. Large deviation theory for coin tossing and turbulence.

    PubMed

    Chakraborty, Sagar; Saha, Arnab; Bhattacharjee, Jayanta K

    2009-11-01

    Large deviations play a significant role in many branches of nonequilibrium statistical physics. They are difficult to handle because their effects, though small, are not amenable to perturbation theory. Even the Gaussian model, which is the usual initial step for most perturbation theories, fails to be a starting point while discussing intermittency in fluid turbulence, where large deviations dominate. Our contention is: in the large deviation theory, the central role is played by the distribution associated with the tossing of a coin and the simple coin toss is the "Gaussian model" of problems where rare events play significant role. We illustrate this by applying it to calculate the multifractal exponents of the order structure factors in fully developed turbulence.

  2. Scaling Deviations for Neutrino Reactions in Aysmptotically Free Field Theories

    DOE R&D Accomplishments Database

    Wilczek, F. A.; Zee, A.; Treiman, S. B.

    1974-11-01

    Several aspects of deep inelastic neutrino scattering are discussed in the framework of asymptotically free field theories. We first consider the growth behavior of the total cross sections at large energies. Because of the deviations from strict scaling which are characteristic of such theories the growth need not be linear. However, upper and lower bounds are established which rather closely bracket a linear growth. We next consider in more detail the expected pattern of scaling deviation for the structure functions and, correspondingly, for the differential cross sections. The analysis here is based on certain speculative assumptions. The focus is on qualitative effects of scaling breakdown as they may show up in the X and y distributions. The last section of the paper deals with deviations from the Callan-Gross relation.

  3. On the cubic velocity deviations in lattice Boltzmann methods

    NASA Astrophysics Data System (ADS)

    Házi, Gábor; Kávrán, Péter

    2006-03-01

    The macroscopic equations derived from the lattice Boltzmann equation are not exactly the Navier-Stokes equations. Here the cubic deviation terms and the methods proposed to eliminate them are studied. The most popular two- and three-dimensional models (D2Q9, D3Q15, D3Q19, D3Q27) are considered in the paper. It is demonstrated that the compensation methods provide only partial elimination of the deviations for these models. It is also shown that the compensation of Qian and Zhou (1998 Europhys. Lett. 42 359) using the compensation parameter K = 1 in a D2Q9 or D3Q27 model can eliminate all the cross terms perfectly, but the deviation terms ∂xρu3x, ∂yρu3y and ∂zρu3z still survive the compensation.

  4. Exact Large Deviation Function in the Asymmetric Exclusion Process

    NASA Astrophysics Data System (ADS)

    Derrida, Bernard; Lebowitz, Joel L.

    1998-01-01

    By an extension of the Bethe ansatz method used by Gwa and Spohn, we obtain an exact expression for the large deviation function of the time averaged current for the fully asymmetric exclusion process in a ring containing N sites and p particles. Using this expression we easily recover the exact diffusion constant obtained earlier and calculate as well some higher cumulants. The distribution of the deviation y of the average current is, in the limit N-->∞, skew and decays like exp-\\(Ay5/2\\) for y-->+∞ and exp-\\(A'\\|y\\|3/2\\) for y-->-∞. Surprisingly, the large deviation function has an expression very similar to the pressure (as a function of the density) of an ideal Bose or Fermi gas in 3D.

  5. The Austrian absolute gravity base net: 27 years of spatial and temporal acquisition of gravity data

    NASA Astrophysics Data System (ADS)

    Ullrich, Christian; Ruess, Diethard

    2014-05-01

    Since 1987 the BEV (Federal Office of Metrology and Surveying) has been operating the absolute gravimeters JILAg-6 and FG5 which are used for basic measurements to determine or review fundamental gravity stations in Austria and abroad. Overall more than 70 absolute gravity stations were installed in Austria and neighbouring countries and some of them have been regularly monitored. A few stations are part of international projects like ECGN (European Combined Geodetic network) and UNIGRACE (Unification of Gravity System in Central and Eastern Europe). As a national metrology institute (NMI) the Metrology Service of the BEV maintains the national standards for the realisation of the legal units of measurement and ensures their international equivalence and recognition. Thus the BEV maintains the national standard for gravimetry in Austria, which is validated and confirmed by international comparisons. Since 1989 the Austrian absolute gravimeters participated seven times in the ICAG's (International Comparison of Absolute Gravimeters) at the BIPM in Paris and Luxemburg and as well participated three times at the ECAG (European Comparison of Absolute Gravimeters) in Luxemburg. The results of these ICAG's and especially the performance of the Austrian absolute gravimeter are reported in this presentation. We also present some examples and interpretation of long time monitoring stations of absolute gravity in several Austrian locations. Some stations are located in large cities like Vienna and Graz and some others are situated in mountainous regions. Mountain stations are at the Conrad Observatory where a SG (Superconducting Gravimeter) is permanently monitoring and in Obergurgl (Tyrolia) at an elevation of approx. 2000 m which is very strong influenced from the glacier retreat.

  6. Phase transitions in large deviations of reset processes

    NASA Astrophysics Data System (ADS)

    Harris, Rosemary J.; Touchette, Hugo

    2017-03-01

    We study the large deviations of additive quantities, such as energy or current, in stochastic processes with intermittent reset. Via a mapping from a discrete-time reset process to the Poland–Scheraga model for DNA denaturation, we derive conditions for observing first-order or continuous dynamical phase transitions in the fluctuations of such quantities and confirm these conditions on simple random walk examples. These results apply to reset Markov processes, but also show more generally that subleading terms in generating functions can lead to non-analyticities in large deviation functions of ‘compound processes’ or ‘random evolutions’ switching stochastically between two or more subprocesses.

  7. Brownian motion: Absolute negative particle mobility

    NASA Astrophysics Data System (ADS)

    Ros, Alexandra; Eichhorn, Ralf; Regtmeier, Jan; Duong, Thanh Tu; Reimann, Peter; Anselmetti, Dario

    2005-08-01

    Noise effects in technological applications, far from being a nuisance, can be exploited with advantage - for example, unavoidable thermal fluctuations have found application in the transport and sorting of colloidal particles and biomolecules. Here we use a microfluidic system to demonstrate a paradoxical migration mechanism in which particles always move in a direction opposite to the net acting force (`absolute negative mobility') as a result of an interplay between thermal noise, a periodic and symmetric microstructure, and a biased alternating-current electric field. This counterintuitive phenomenon could be used for bioanalytical purposes, for example in the separation and fractionation of colloids, biological molecules and cells.

  8. Arbitrary segments of absolute negative mobility

    NASA Astrophysics Data System (ADS)

    Chen, Ruyin; Nie, Linru; Chen, Chongyang; Wang, Chaojie

    2017-01-01

    In previous research work, investigators have reported only one or two segments of absolute negative mobility (ANM) in a periodic potential. In fact, many segments of ANM also occur in the system considered here. We investigate transport of an inertial particle in a gating ratchet periodic potential subjected to a constant bias force. Our numerical results show that its mean velocity can decrease with the bias force increasing, i.e. ANM phenomenon. Furthermore, the ANM can take place arbitrary segments, even up to more than thirty. Intrinsic physical mechanism and conditions for arbitrary segments of ANM to occur are discussed in detail.

  9. Absolute quantification of myocardial blood flow.

    PubMed

    Yoshinaga, Keiichiro; Manabe, Osamu; Tamaki, Nagara

    2016-07-21

    With the increasing availability of positron emission tomography (PET) myocardial perfusion imaging, the absolute quantification of myocardial blood flow (MBF) has become popular in clinical settings. Quantitative MBF provides an important additional diagnostic or prognostic information over conventional visual assessment. The success of MBF quantification using PET/computed tomography (CT) has increased the demand for this quantitative diagnostic approach to be more accessible. In this regard, MBF quantification approaches have been developed using several other diagnostic imaging modalities including single-photon emission computed tomography, CT, and cardiac magnetic resonance. This review will address the clinical aspects of PET MBF quantification and the new approaches to MBF quantification.

  10. An absolute radius scale for Saturn's rings

    NASA Technical Reports Server (NTRS)

    Nicholson, Philip D.; Cooke, Maren L.; Pelton, Emily

    1990-01-01

    Radio and stellar occultation observations of Saturn's rings made by the Voyager spacecraft are discussed. The data reveal systematic discrepancies of almost 10 km in some parts of the rings, limiting some of the investigations. A revised solution for Saturn's rotation pole has been proposed which removes the discrepancies between the stellar and radio occultation profiles. Corrections to previously published radii vary from -2 to -10 km for the radio occultation, and +5 to -6 km for the stellar occultation. An examination of spiral density waves in the outer A Ring supports that the revised absolute radii are in error by no more than 2 km.

  11. Absolute Rate Theories of Epigenetic Stability

    NASA Astrophysics Data System (ADS)

    Walczak, Aleksandra M.; Onuchic, Jose N.; Wolynes, Peter G.

    2006-03-01

    Spontaneous switching events in most characterized genetic switches are rare, resulting in extremely stable epigenetic properties. We show how simple arguments lead to theories of the rate of such events much like the absolute rate theory of chemical reactions corrected by a transmission factor. Both the probability of the rare cellular states that allow epigenetic escape, and the transmission factor, depend on the rates of DNA binding and unbinding events and on the rates of protein synthesis and degradation. Different mechanisms of escape from the stable attractors occur in the nonadiabatic, weakly adiabatic and strictly adiabatic regimes, characterized by the relative values of those input rates.

  12. Absolute rate theories of epigenetic stability

    NASA Astrophysics Data System (ADS)

    Walczak, Aleksandra M.; Onuchic, José N.; Wolynes, Peter G.

    2005-12-01

    Spontaneous switching events in most characterized genetic switches are rare, resulting in extremely stable epigenetic properties. We show how simple arguments lead to theories of the rate of such events much like the absolute rate theory of chemical reactions corrected by a transmission factor. Both the probability of the rare cellular states that allow epigenetic escape and the transmission factor depend on the rates of DNA binding and unbinding events and on the rates of protein synthesis and degradation. Different mechanisms of escape from the stable attractors occur in the nonadiabatic, weakly adiabatic, and strictly adiabatic regimes, characterized by the relative values of those input rates. rate theory | stochastic gene expression | gene switches

  13. Absolute Priority for a Vehicle in VANET

    NASA Astrophysics Data System (ADS)

    Shirani, Rostam; Hendessi, Faramarz; Montazeri, Mohammad Ali; Sheikh Zefreh, Mohammad

    In today's world, traffic jams waste hundreds of hours of our life. This causes many researchers try to resolve the problem with the idea of Intelligent Transportation System. For some applications like a travelling ambulance, it is important to reduce delay even for a second. In this paper, we propose a completely infrastructure-less approach for finding shortest path and controlling traffic light to provide absolute priority for an emergency vehicle. We use the idea of vehicular ad-hoc networking to reduce the imposed travelling time. Then, we simulate our proposed protocol and compare it with a centrally controlled traffic light system.

  14. ABSOLUTE PROPERTIES OF THE ECLIPSING BINARY STAR V335 SERPENTIS

    SciTech Connect

    Lacy, Claud H. Sandberg; Fekel, Francis C.; Claret, Antonio E-mail: fekel@evans.tsuniv.edu

    2012-08-15

    V335 Ser is now known to be an eccentric double-lined A1+A3 binary star with fairly deep (0.5 mag) partial eclipses. Previous studies of the system are improved with 7456 differential photometric observations from the URSA WebScope and 5666 from the NFO WebScope, and 67 high-resolution spectroscopic observations from the Tennessee State University 2 m automatic spectroscopic telescope. From dates of minima, the apsidal period is about 880 years. Accurate (better than 2%) masses and radii are determined from analysis of the two new light curves and the radial velocity curve. Theoretical models match the absolute properties of the stars at an age of about 380 Myr, though the age agreement for the two components is poor. Tidal theory correctly confirms that the orbit should still be eccentric, but we find that standard tidal theory is unable to match the observed asynchronous rotation rates of the components' surface layers.

  15. MUSiC - A Generic Search for Deviations from Monte Carlo Predictions in CMS

    NASA Astrophysics Data System (ADS)

    Hof, Carsten

    2009-05-01

    We present a model independent analysis approach, systematically scanning the data for deviations from the Standard Model Monte Carlo expectation. Such an analysis can contribute to the understanding of the CMS detector and the tuning of the event generators. Furthermore, due to the minimal theoretical bias this approach is sensitive to a variety of models of new physics, including those not yet thought of. Events are classified into event classes according to their particle content (muons, electrons, photons, jets and missing transverse energy). A broad scan of various distributions is performed, identifying significant deviations from the Monte Carlo simulation. We outline the importance of systematic uncertainties, which are taken into account rigorously within the algorithm. Possible detector effects and generator issues, as well as models involving supersymmetry and new heavy gauge bosons have been used as an input to the search algorithm.

  16. Absolute Calibration of the AXAF Telescope Effective Area

    NASA Technical Reports Server (NTRS)

    Kellogg, E.; Cohen, L.; Edgar, R.; Evans, I.; Freeman, M.; Gaetz, T.; Jerius, D.; McDermott, W. C.; McKinnon, P.; Murray, S.; Podgorski, W.; Schwartz, D.; VanSpeybroeck, L.; Wargelin, B.; Zombeck, M.; Weisskopf, M.; Elsner, R.; ODell, S.; Tennant, A.; Kolodziejczak, J.

    1997-01-01

    The prelaunch calibration of AXAF encompasses many aspects of the telescope. In principle, all that is needed is the complete point response function. This is, however, a function of energy, off-axis angle of the source, and operating mode of the facility. No single measurement would yield the entire result. Also, any calibration made prior to launch will be affected by changes in conditions after launch, such as the change from one g to zero g. The reflectivity of the mirror and perhaps even the detectors can change as well, for example by addition or removal of small amounts of material deposited on their surfaces. In this paper, we give a broad view of the issues in performing such a calibration, and discuss how they are being addressed in prelaunch preparation of AXAF. As our title indicates, we concentrate here on the total throughput of the observatory. This can be thought of as the integral of the point response function, i.e. the encircled energy, out ot the largest practical solid angle for an observation. Since there is no standard x-ray source in the sky whose flux is known to the -1% accuracy we are trying to achieve, we must do this calibration on the ground. we also must provide a means for monitoring any possible changes in this calibration from pre-launch until on-orbit operation can transfer the calibration to a celestial x-ray source whose emission is stable. In this paper, we analyze the elements of the absolute throughput calibration, which we call Effective Area. We review the requirements for calibrations of components or subsystems of the AXAF facility, including mirror, detectors, and gratings. We show how it is necessary to calibrate this ground-based detection system at standard man-made x-ray sources, such as electron storage rings. We present the status of all these calibrations, with indications of the measurements remaining to be done, even though the measurements on the AXAF flight optics and detectors will have been completed by the

  17. 21 CFR 211.100 - Written procedures; deviations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Written procedures; deviations. 211.100 Section 211.100 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) DRUGS: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR FINISHED PHARMACEUTICALS Production...

  18. 21 CFR 114.89 - Deviations from scheduled processes.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Deviations from scheduled processes. 114.89 Section 114.89 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION ACIDIFIED FOODS Production and Process Controls § 114.89...

  19. 21 CFR 114.89 - Deviations from scheduled processes.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Deviations from scheduled processes. 114.89 Section 114.89 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION ACIDIFIED FOODS Production and Process Controls § 114.89...

  20. 21 CFR 114.89 - Deviations from scheduled processes.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 2 2014-04-01 2014-04-01 false Deviations from scheduled processes. 114.89 Section 114.89 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION ACIDIFIED FOODS Production and Process Controls § 114.89...

  1. 21 CFR 114.89 - Deviations from scheduled processes.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 2 2013-04-01 2013-04-01 false Deviations from scheduled processes. 114.89 Section 114.89 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION ACIDIFIED FOODS Production and Process Controls § 114.89...

  2. 40 CFR 35.6025 - Deviation from this subpart.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 1 2014-07-01 2014-07-01 false Deviation from this subpart. 35.6025 Section 35.6025 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for...

  3. 40 CFR 35.6025 - Deviation from this subpart.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 1 2011-07-01 2011-07-01 false Deviation from this subpart. 35.6025 Section 35.6025 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for...

  4. 40 CFR 35.6025 - Deviation from this subpart.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Deviation from this subpart. 35.6025 Section 35.6025 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for...

  5. 40 CFR 35.6025 - Deviation from this subpart.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 1 2013-07-01 2013-07-01 false Deviation from this subpart. 35.6025 Section 35.6025 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for...

  6. 40 CFR 35.6025 - Deviation from this subpart.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 1 2012-07-01 2012-07-01 false Deviation from this subpart. 35.6025 Section 35.6025 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL ASSISTANCE STATE AND LOCAL ASSISTANCE Cooperative Agreements and Superfund State Contracts for...

  7. 33 CFR 151.2055 - Deviation from planned voyage.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., AND BALLAST WATER Ballast Water Management for Control of Nonindigenous Species in Waters of the United States § 151.2055 Deviation from planned voyage. As long as ballast water exchange (BWE) is an allowable ballast water management option under §§ 151.2025 and 151.2035 of this subpart, the Coast...

  8. 33 CFR 151.2055 - Deviation from planned voyage.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., AND BALLAST WATER Ballast Water Management for Control of Nonindigenous Species in Waters of the United States § 151.2055 Deviation from planned voyage. As long as ballast water exchange (BWE) is an allowable ballast water management option under §§ 151.2025 and 151.2035 of this subpart, the Coast...

  9. 33 CFR 151.2055 - Deviation from planned voyage.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., AND BALLAST WATER Ballast Water Management for Control of Nonindigenous Species in Waters of the United States § 151.2055 Deviation from planned voyage. As long as ballast water exchange (BWE) is an allowable ballast water management option under §§ 151.2025 and 151.2035 of this subpart, the Coast...

  10. Identifying specific erotic cues in sexual deviations by audiotaped descriptions.

    PubMed Central

    Abel, G G; Blanchard, E B; Barlow, D H; Mavissakalian, M

    1975-01-01

    Using audiotaped descriptions of sexual experiences and a direct measure of penile erection, it is possible to specify more precisely erotic cues in sexual deviates. Results indicated that such cues are highly idiosyncratic. Some tentative conclusions and suggested application for the method are discussed. PMID:1184490

  11. 45 CFR 63.19 - Budget revisions and minor deviations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 45 Public Welfare 1 2011-10-01 2011-10-01 false Budget revisions and minor deviations. 63.19 Section 63.19 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION GRANT PROGRAMS ADMINISTERED BY THE OFFICE OF THE ASSISTANT SECRETARY FOR PLANNING AND EVALUATION Financial Provisions §...

  12. 48 CFR 927.403 - Negotiations and deviations.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Negotiations and deviations. 927.403 Section 927.403 Federal Acquisition Regulations System DEPARTMENT OF ENERGY GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Technical Data and Copyrights 927.403 Negotiations...

  13. 48 CFR 927.403 - Negotiations and deviations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Negotiations and deviations. 927.403 Section 927.403 Federal Acquisition Regulations System DEPARTMENT OF ENERGY GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Technical Data and Copyrights 927.403 Negotiations...

  14. 48 CFR 927.403 - Negotiations and deviations.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Negotiations and deviations. 927.403 Section 927.403 Federal Acquisition Regulations System DEPARTMENT OF ENERGY GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Technical Data and Copyrights 927.403 Negotiations...

  15. Large Deviation Analysis of Rapid Onset of Rain Showers

    NASA Astrophysics Data System (ADS)

    Wilkinson, Michael

    2016-01-01

    Rainfall from ice-free cumulus clouds requires collisions of large numbers of microscopic droplets to create every raindrop. The onset of rain showers can be surprisingly rapid, much faster than the mean time required for a single collision. Large-deviation theory is used to explain this observation.

  16. 46 CFR 385.9 - Exceptions, deviations, or waivers.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false Exceptions, deviations, or waivers. 385.9 Section 385.9 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION MISCELLANEOUS RESEARCH AND DEVELOPMENT GRANT... Management and Budget when required by law or other applicable Federal requirement. Definition of Terms...

  17. 21 CFR 114.89 - Deviations from scheduled processes.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Deviations from scheduled processes. 114.89 Section 114.89 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) FOOD FOR HUMAN CONSUMPTION ACIDIFIED FOODS Production and Process Controls § 114.89...

  18. 24. DETAIL VIEW OF COLUMN #072 DEVIATING FROM VERTICAL IN ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    24. DETAIL VIEW OF COLUMN #072 DEVIATING FROM VERTICAL IN ROW OF INTACT COLUMNS, LOOKING NORTHEAST TO SOUTHWEST. (NOTE BOLTED BLOCK SCABBED TO COLUMN AS JOIST/TRUSS SUPPORT) - Oakland Army Base, Transit Shed, East of Dunkirk Street & South of Burma Road, Oakland, Alameda County, CA

  19. 9 CFR 381.308 - Deviations in processing.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AGENCY ORGANIZATION AND TERMINOLOGY; MANDATORY MEAT AND POULTRY PRODUCTS INSPECTION AND VOLUNTARY...) must be handled according to: (1)(i) A HACCP plan for canned product that addresses hazards associated... (d) of this section. (c) (d) Procedures for handling process deviations where the HACCP plan...

  20. Deviation-Amplifying Processes and Individual Human Growth and Behavior.

    ERIC Educational Resources Information Center

    Steg, Doreen Ray; And Others

    The purpose of this study was to inquire into the relation of intellectual and/or psycho-linguistic development and apparent improvement in other behavior factors such as affective and social behavior and development. Thus consideration is given to the second cybernetics (i.e. the concept of positive feedback or deviation-amplifying relationships…

  1. Current Large Deviations for Asymmetric Exclusion Processes with Open Boundaries

    NASA Astrophysics Data System (ADS)

    Bodineau, T.; Derrida, B.

    2006-04-01

    We study the large deviation functional of the current for the Weakly Asymmetric Simple Exclusion Process in contact with two reservoirs. We compare this functional in the large drift limit to the one of the Totally Asymmetric Simple Exclusion Process, in particular to the Jensen-Varadhan functional. Conjectures for generalizing the Jensen-Varadhan functional to open systems are also stated.

  2. Moderate- and Large- Deviation Probabilities in Actuarial Risk Theory,

    DTIC Science & Technology

    1988-06-01

    Introduction to the Theory of Large Deviations, Springer-Verlag, New York. Thorin, 0. (1982), Probabilities of ruin, Scand. Actuar . Jour. 65-102. 25 *% 0 I S 0 S 3 9 I bJ\\~ S S I’ C..., S L2JI1C S ~

  3. 45 CFR 63.19 - Budget revisions and minor deviations.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Budget revisions and minor deviations. 63.19 Section 63.19 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION GRANT PROGRAMS ADMINISTERED BY THE OFFICE OF THE ASSISTANT SECRETARY FOR PLANNING AND EVALUATION Financial Provisions §...

  4. 9 CFR 381.308 - Deviations in processing.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... shall maintain full records regarding the handling of each deviation. Such records shall include, at a minimum, the appropriate processing and production records, a full description of the corrective actions... establishment shall: (i) Immediately reprocess the product using the full process schedule; or, (ii) Use...

  5. 9 CFR 381.308 - Deviations in processing.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... shall maintain full records regarding the handling of each deviation. Such records shall include, at a minimum, the appropriate processing and production records, a full description of the corrective actions... establishment shall: (i) Immediately reprocess the product using the full process schedule; or, (ii) Use...

  6. Linear ultrasonic motor for absolute gravimeter.

    PubMed

    Jian, Yue; Yao, Zhiyuan; Silberschmidt, Vadim V

    2017-02-01

    Thanks to their compactness and suitability for vacuum applications, linear ultrasonic motors are considered as substitutes for classical electromagnetic motors as driving elements in absolute gravimeters. Still, their application is prevented by relatively low power output. To overcome this limitation and provide better stability, a V-type linear ultrasonic motor with a new clamping method is proposed for a gravimeter. In this paper, a mechanical model of stators with flexible clamping components is suggested, according to a design criterion for clamps of linear ultrasonic motors. After that, an effect of tangential and normal rigidity of the clamping components on mechanical output is studied. It is followed by discussion of a new clamping method with sufficient tangential rigidity and a capability to facilitate pre-load. Additionally, a prototype of the motor with the proposed clamping method was fabricated and the performance tests in vertical direction were implemented. Experimental results show that the suggested motor has structural stability and high dynamic performance, such as no-load speed of 1.4m/s and maximal thrust of 43N, meeting the requirements for absolute gravimeters.

  7. Why to compare absolute numbers of mitochondria.

    PubMed

    Schmitt, Sabine; Schulz, Sabine; Schropp, Eva-Maria; Eberhagen, Carola; Simmons, Alisha; Beisker, Wolfgang; Aichler, Michaela; Zischka, Hans

    2014-11-01

    Prompted by pronounced structural differences between rat liver and rat hepatocellular carcinoma mitochondria, we suspected these mitochondrial populations to differ massively in their molecular composition. Aiming to reveal these mitochondrial differences, we came across the issue on how to normalize such comparisons and decided to focus on the absolute number of mitochondria. To this end, fluorescently stained mitochondria were quantified by flow cytometry. For rat liver mitochondria, this approach resulted in mitochondrial protein contents comparable to earlier reports using alternative methods. We determined similar protein contents for rat liver, heart and kidney mitochondria. In contrast, however, lower protein contents were determined for rat brain mitochondria and for mitochondria from the rat hepatocellular carcinoma cell line McA 7777. This result challenges mitochondrial comparisons that rely on equal protein amounts as a typical normalization method. Exemplarily, we therefore compared the activity and susceptibility toward inhibition of complex II of rat liver and hepatocellular carcinoma mitochondria and obtained significant discrepancies by either normalizing to protein amount or to absolute mitochondrial number. Importantly, the latter normalization, in contrast to the former, demonstrated a lower complex II activity and higher susceptibility toward inhibition in hepatocellular carcinoma mitochondria compared to liver mitochondria. These findings demonstrate that solely normalizing to protein amount may obscure essential molecular differences between mitochondrial populations.

  8. The absolute threshold of cone vision

    PubMed Central

    Koeing, Darran; Hofer, Heidi

    2013-01-01

    We report measurements of the absolute threshold of cone vision, which has been previously underestimated due to sub-optimal conditions or overly strict subjective response criteria. We avoided these limitations by using optimized stimuli and experimental conditions while having subjects respond within a rating scale framework. Small (1′ fwhm), brief (34 msec), monochromatic (550 nm) stimuli were foveally presented at multiple intensities in dark-adapted retina for 5 subjects. For comparison, 4 subjects underwent similar testing with rod-optimized stimuli. Cone absolute threshold, that is, the minimum light energy for which subjects were just able to detect a visual stimulus with any response criterion, was 203 ± 38 photons at the cornea, ∼0.47 log units lower than previously reported. Two-alternative forced-choice measurements in a subset of subjects yielded consistent results. Cone thresholds were less responsive to criterion changes than rod thresholds, suggesting a limit to the stimulus information recoverable from the cone mosaic in addition to the limit imposed by Poisson noise. Results were consistent with expectations for detection in the face of stimulus uncertainty. We discuss implications of these findings for modeling the first stages of human cone vision and interpreting psychophysical data acquired with adaptive optics at the spatial scale of the receptor mosaic. PMID:21270115

  9. [Estimation of absolute risk for fracture].

    PubMed

    Fujiwara, Saeko

    2009-03-01

    Osteoporosis treatment aims to prevent fractures and maintain the QOL of the elderly. However, persons at high risk of future fracture cannot be effectively identified on the basis of bone density (BMD) alone, although BMD is used as an diagnostic criterion. Therefore, the WHO recommended that absolute risk for fracture (10-year probability of fracture) for each individual be evaluated and used as an index for intervention threshold. The 10-year probability of fracture is calculated based on age, sex, BMD at the femoral neck (body mass index if BMD is not available), history of previous fractures, parental hip fracture history, smoking, steroid use, rheumatoid arthritis, secondary osteoporosis and alcohol consumption. The WHO has just announced the development of a calculation tool (FRAX: WHO Fracture Risk Assessment Tool) in February this year. Fractures could be prevented more effectively if, based on each country's medical circumstances, an absolute risk value for fracture to determine when to start medical treatment is established and persons at high risk of fracture are identified and treated accordingly.

  10. Absolute stereochemistry of altersolanol A and alterporriols.

    PubMed

    Kanamaru, Saki; Honma, Miho; Murakami, Takanori; Tsushima, Taro; Kudo, Shinji; Tanaka, Kazuaki; Nihei, Ken-Ichi; Nehira, Tatsuo; Hashimoto, Masaru

    2012-02-01

    The absolute stereochemistry of altersolanol A (1) was established by observing a positive exciton couplet in the circular dichroism (CD) spectrum of the C3,C4-O-bis(2-naphthoyl) derivative 10 and by chemical correlations with known compound 8. Before the discussion, the relative stereochemistry of 1 was confirmed by X-ray crystallographic analysis. The shielding effect at C7'-OMe group by C1-O-benzoylation established the relative stereochemical relationship between the C8-C8' axial bonding and the C1-C4/C1'-C4' polyol moieties of alterporriols E (3), an atropisomer of the C8-C8' dimer of 1. As 3 could be obtained by dimerization of 1 in vitro, the absolute configuration of its central chirality elements (C1-C4) must be identical to those of 1. Spectral comparison between the experimental and theoretical CD spectra supported the above conclusion. Axial stereochemistry of novel C4-O-deoxy dimeric derivatives, alterporriols F (4) and G (5), were also revealed by comparison of their CD spectra to those of 2 and 3.

  11. Absolute Electron Extraction Efficiency of Liquid Xenon

    NASA Astrophysics Data System (ADS)

    Kamdin, Katayun; Mizrachi, Eli; Morad, James; Sorensen, Peter

    2016-03-01

    Dual phase liquid/gas xenon time projection chambers (TPCs) currently set the world's most sensitive limits on weakly interacting massive particles (WIMPs), a favored dark matter candidate. These detectors rely on extracting electrons from liquid xenon into gaseous xenon, where they produce proportional scintillation. The proportional scintillation from the extracted electrons serves to internally amplify the WIMP signal; even a single extracted electron is detectable. Credible dark matter searches can proceed with electron extraction efficiency (EEE) lower than 100%. However, electrons systematically left at the liquid/gas boundary are a concern. Possible effects include spontaneous single or multi-electron proportional scintillation signals in the gas, or charging of the liquid/gas interface or detector materials. Understanding EEE is consequently a serious concern for this class of rare event search detectors. Previous EEE measurements have mostly been relative, not absolute, assuming efficiency plateaus at 100%. I will present an absolute EEE measurement with a small liquid/gas xenon TPC test bed located at Lawrence Berkeley National Laboratory.

  12. Swarm's Absolute Scalar Magnetometers Burst Mode Results

    NASA Astrophysics Data System (ADS)

    Coisson, P.; Vigneron, P.; Hulot, G.; Crespo Grau, R.; Brocco, L.; Lalanne, X.; Sirol, O.; Leger, J. M.; Jager, T.; Bertrand, F.; Boness, A.; Fratter, I.

    2014-12-01

    Each of the three Swarm satellites embarks an Absolute Scalar Magnetometer (ASM) to provide absolute scalar measurements of the magnetic field with high accuracy and stability. Nominal data acquisition of these ASMs is 1 Hz. But they can also run in a so-called "burst mode" and provide data at 250 Hz. During the commissioning phase of the mission, seven burst mode acquisition campaigns have been run simultaneously for all satellites, obtaining a total of ten days of burs-mode data. These campaigns allowed the identification of issues related to the operations of the piezo-electric motor and the heaters connected to the ASM, that do not impact the nominal 1 Hz scalar data. We analyze the burst mode data to identify high frequency geomagnetic signals, focusing the analysis in two regions: the low latitudes, where we seek signatures of ionospheric irregularities, and the high latitudes, to identify high frequency signals related to polar region currents. Since these campaigns have been conducted during the initial months of the mission, the three satellites where still close to each other, allowing to analyze the spatial coherency of the signals. Wavelet analysis have revealed 31 Hz signals appearing in the night-side in the equatorial region.

  13. Absolute activity measurement of radon gas at IRA-METAS

    NASA Astrophysics Data System (ADS)

    Spring, Philippe; Nedjadi, Youcef; Bailat, Claude; Triscone, Gilles; Bochud, François

    2006-12-01

    This paper describes the system of the Swiss national metrological institute (IRA-METAS) for the absolute standardisation of radon gas. This method relies on condensing radon under vacuum conditions within a specified cold area using a cryogenerator, and detecting its alpha particles with an ion-implanted silicon detector, through a very accurately defined solid angle. The accuracy of this defined solid angle standardisation technique was corroborated by another primary measurement method involving 4 πγ NaI(Tl) integral counting and Monte Carlo efficiency calculations. The 222Rn standard submitted by IRA-METAS to the Système International de Référence (SIR) at the Bureau International des Poids et Mesures (BIPM) has also been found to be consistent with an analogous standard submitted by the German national metrological institute (PTB). IRA-METAS is able to deliver radon standards, with activities ranging from a few kBq to 350 kBq, in NIST-Type ampoules, and glass or steel containers usable for calibrating radon-measuring instruments.

  14. SNR and Standard Deviation of cGNSS-R and iGNSS-R Scatterometric Measurements.

    PubMed

    Alonso-Arroyo, Alberto; Querol, Jorge; Lopez-Martinez, Carlos; Zavorotny, Valery U; Park, Hyuk; Pascual, Daniel; Onrubia, Raul; Camps, Adriano

    2017-01-19

    This work addresses the accuracy of the Global Navigation Satellite Systems (GNSS)-Reflectometry (GNSS-R) scatterometric measurements considering the presence of both coherent and incoherent scattered components, for both conventional GNSS-R (cGNSS-R) and interferometric GNSS-R (iGNSS-R) techniques. The coherent component is present for some type of surfaces, and it has been neglected until now because it vanishes for the sea surface scattering case. Taking into account the presence of both scattering components, the estimated Signal-to-Noise Ratio (SNR) for both techniques is computed based on the detectability criterion, as it is done in conventional GNSS applications. The non-coherent averaging operation is considered from a general point of view, taking into account that thermal noise contributions can be reduced by an extra factor of 0.88 dB when using partially overlapped or partially correlated samples. After the SNRs are derived, the received waveform's peak variability is computed, which determines the system's capability to measure geophysical parameters. This theoretical derivations are applied to the United Kingdom (UK) TechDemoSat-1 (UK TDS-1) and to the future GNSS REflectometry, Radio Occultation and Scatterometry on board the International Space Station (ISS) (GEROS-ISS) scenarios, in order to estimate the expected scatterometric performance of both missions.

  15. SNR and Standard Deviation of cGNSS-R and iGNSS-R Scatterometric Measurements

    PubMed Central

    Alonso-Arroyo, Alberto; Querol, Jorge; Lopez-Martinez, Carlos; Zavorotny, Valery U.; Park, Hyuk; Pascual, Daniel; Onrubia, Raul; Camps, Adriano

    2017-01-01

    This work addresses the accuracy of the Global Navigation Satellite Systems (GNSS)-Reflectometry (GNSS-R) scatterometric measurements considering the presence of both coherent and incoherent scattered components, for both conventional GNSS-R (cGNSS-R) and interferometric GNSS-R (iGNSS-R) techniques. The coherent component is present for some type of surfaces, and it has been neglected until now because it vanishes for the sea surface scattering case. Taking into account the presence of both scattering components, the estimated Signal-to-Noise Ratio (SNR) for both techniques is computed based on the detectability criterion, as it is done in conventional GNSS applications. The non-coherent averaging operation is considered from a general point of view, taking into account that thermal noise contributions can be reduced by an extra factor of 0.88 dB when using partially overlapped or partially correlated samples. After the SNRs are derived, the received waveform’s peak variability is computed, which determines the system’s capability to measure geophysical parameters. This theoretical derivations are applied to the United Kingdom (UK) TechDemoSat-1 (UK TDS-1) and to the future GNSS REflectometry, Radio Occultation and Scatterometry on board the International Space Station (ISS) (GEROS-ISS) scenarios, in order to estimate the expected scatterometric performance of both missions. PMID:28106825

  16. A Vertical Wind Angle Standard Deviation Calculation Method for the Unstable Surface Boundary Layer.

    DTIC Science & Technology

    1983-08-01

    UT C ILTOFT RUG 63 UNCLASSIFIED DPG-TR -3 41 F6 4/ 2L .41 L5.04 1111LA. 1 1112.0- 11111 .5 ~ ?"IIIII 111111. MICROCOPY RESOLUTION TEST CHART NATIONAL ...equation (16). R-Fg = F1 + Fh (16) Swinbank (1964) tabulated R and F data taken at an open field near Kerang, Australia under a variety of weater ...Addressee Copies Di rector 1 National Oceanic and Atmospheric Administration Environmental Research Laboratories Boulder, CO 80302 Cooperative

  17. Rating Slam Dunks to Visualize the Mean, Median, Mode, Range, and Standard Deviation

    ERIC Educational Resources Information Center

    Robinson, Nick W.; Castle Bell, Gina

    2014-01-01

    Among the many difficulties beleaguering the communication research methods instructor is the problem of contextualizing abstract ideas. Comprehension of variable operationalization, the utility of the measures of central tendency, measures of dispersion, and the visual distribution of data sets are difficult, since students have not handled data.…

  18. Doppler standard deviation imaging for clinical monitoring of in vivo human skin blood flow

    SciTech Connect

    Zhao, Yonghua; Chen, Zhongping; Saxer, Christopher; Shen, Qimin; Xiang, Shaohua; Boer, Johannes F. de; Nelson, J. Stuart

    2000-09-15

    We used a novel phase-resolved optical Doppler tomographic (ODT) technique with very high flow-velocity sensitivity (10 {mu}m/s) and high spatial resolution (10 {mu}m) to image blood flow in port-wine stain (PWS) birthmarks in human skin. In addition to the regular ODT velocity and structural images, we use the variance of blood flow velocity to map the PWS vessels. Our device combines ODT and therapeutic systems such that PWS blood flow can be monitored in situ before and after laser treatment. To the authors' knowledge this is the first clinical application of ODT to provide a fast semiquantitative evaluation of the efficacy of PWS laser therapy in situ and in real time. (c) 2000 Optical Society of America.

  19. 78 FR 2273 - Canned Tuna Deviating From Identity Standard; Temporary Permit for Market Testing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-10

    ... INFORMATION CONTACT: Loretta A. Carey, Center for Food Safety and Applied Nutrition (HFS-820), Food and Drug..., and Cosmetic Act (21 U.S.C. 341). ] The permit covers limited interstate marketing tests of products... panels on the labels of the test products must bear nutrition labeling in accordance with 21 CFR...

  20. Extracting infrared absolute reflectance from relative reflectance measurements.

    PubMed

    Berets, Susan L; Milosevic, Milan

    2012-06-01

    Absolute reflectance measurements are valuable to the optics industry for development of new materials and optical coatings. Yet, absolute reflectance measurements are notoriously difficult to make. In this paper, we investigate the feasibility of extracting the absolute reflectance from a relative reflectance measurement using a reference material with known refractive index.

  1. A Conceptual Approach to Absolute Value Equations and Inequalities

    ERIC Educational Resources Information Center

    Ellis, Mark W.; Bryson, Janet L.

    2011-01-01

    The absolute value learning objective in high school mathematics requires students to solve far more complex absolute value equations and inequalities. When absolute value problems become more complex, students often do not have sufficient conceptual understanding to make any sense of what is happening mathematically. The authors suggest that the…

  2. Ultraviolet photometry from the Orbiting Astronomical Observatory. XXI - Absolute energy distribution of stars in the ultraviolet

    NASA Technical Reports Server (NTRS)

    Bless, R. C.; Code, A. D.; Fairchild, E. T.

    1976-01-01

    The absolute energy distribution in the ultraviolet is given for the stars alpha Vir, eta UMa, and alpha Leo. The calibration is based on absolute heterochromatic photometry between 2920 and 1370 A carried out with an Aerobee sounding rocket. The fundamental radiation standard is the synchrotron radiation from 240-MeV electrons in a certain synchrotron storage ring. On the basis of the sounding-rocket calibration, the preliminary OAO-2 spectrometer calibration has been revised; the fluxes for the three program stars are tabulated in energy per second per square centimeter per unit wavelength interval.

  3. Absolute calibration of a soft X-ray spectrograph for X-ray laser research using white beam.

    PubMed

    Fujikawa, C; Kawachi, T; Ando, K; Yamaguchi, N; Hara, T

    1998-05-01

    Absolute calibration of a soft X-ray spectrograph has been performed using a white beam of synchrotron radiation. The calibrated spectrograph was a flat-field grazing-incidence spectrograph with an X-ray CCD detector for X-ray laser research. Absolute sensitivity of the spectrograph system can be obtained from transmitted spectra using filters made of several different materials, each providing an absorption-edge wavelength standard. The absolute sensitivity determined in this work shows nearly the same behaviour with wavelength as that in another calibration experiment using a laser-produced plasma as an X-ray source.

  4. Use of Absolute and Comparative Performance Feedback in Absolute and Comparative Judgments and Decisions

    ERIC Educational Resources Information Center

    Moore, Don A.; Klein, William M. P.

    2008-01-01

    Which matters more--beliefs about absolute ability or ability relative to others? This study set out to compare the effects of such beliefs on satisfaction with performance, self-evaluations, and bets on future performance. In Experiment 1, undergraduate participants were told they had answered 20% correct, 80% correct, or were not given their…

  5. Absolute nonlocality via distributed computing without communication

    NASA Astrophysics Data System (ADS)

    Czekaj, Ł.; Pawłowski, M.; Vértesi, T.; Grudka, A.; Horodecki, M.; Horodecki, R.

    2015-09-01

    Understanding the role that quantum entanglement plays as a resource in various information processing tasks is one of the crucial goals of quantum information theory. Here we propose an alternative perspective for studying quantum entanglement: distributed computation of functions without communication between nodes. To formalize this approach, we propose identity games. Surprisingly, despite no signaling, we obtain that nonlocal quantum strategies beat classical ones in terms of winning probability for identity games originating from certain bipartite and multipartite functions. Moreover we show that, for a majority of functions, access to general nonsignaling resources boosts success probability two times in comparison to classical ones for a number of large enough outputs. Because there are no constraints on the inputs and no processing of the outputs in the identity games, they detect very strong types of correlations: absolute nonlocality.

  6. In vivo absorption spectroscopy for absolute measurement.

    PubMed

    Furukawa, Hiromitsu; Fukuda, Takashi

    2012-10-01

    In in vivo spectroscopy, there are differences between individual subjects in parameters such as tissue scattering and sample concentration. We propose a method that can provide the absolute value of a particular substance concentration, independent of these individual differences. Thus, it is not necessary to use the typical statistical calibration curve, which assumes an average level of scattering and an averaged concentration over individual subjects. This method is expected to greatly reduce the difficulties encountered during in vivo measurements. As an example, for in vivo absorption spectroscopy, the method was applied to the reflectance measurement in retinal vessels to monitor their oxygen saturation levels. This method was then validated by applying it to the tissue phantom under a variety of absorbance values and scattering efficiencies.

  7. Determining Absolute Zero Using a Tuning Fork

    NASA Astrophysics Data System (ADS)

    Goldader, Jeffrey D.

    2008-04-01

    The Celsius and Kelvin temperature scales, we tell our students, are related. We explain that a change in temperature of 1°C corresponds to a change of 1 Kelvin and that atoms and molecules have zero kinetic energy at zero Kelvin, -273°C. In this paper, we will show how students can derive the relationship between the Celsius and Kelvin temperature scales using a simple, well-known physics experiment. By making multiple measurements of the speed of sound at different temperatures, using the classic physics experiment of determining the speed of sound with a tuning fork and variable-length tube, they can determine the temperature at which the speed of sound is zero—absolute zero.

  8. MAGSAT: Vector magnetometer absolute sensor alignment determination

    NASA Technical Reports Server (NTRS)

    Acuna, M. H.

    1981-01-01

    A procedure is described for accurately determining the absolute alignment of the magnetic axes of a triaxial magnetometer sensor with respect to an external, fixed, reference coordinate system. The method does not require that the magnetic field vector orientation, as generated by a triaxial calibration coil system, be known to better than a few degrees from its true position, and minimizes the number of positions through which a sensor assembly must be rotated to obtain a solution. Computer simulations show that accuracies of better than 0.4 seconds of arc can be achieved under typical test conditions associated with existing magnetic test facilities. The basic approach is similar in nature to that presented by McPherron and Snare (1978) except that only three sensor positions are required and the system of equations to be solved is considerably simplified. Applications of the method to the case of the MAGSAT Vector Magnetometer are presented and the problems encountered discussed.

  9. An estimate of global absolute dynamic topography

    NASA Technical Reports Server (NTRS)

    Tai, C.-K.; Wunsch, C.

    1984-01-01

    The absolute dynamic topography of the world ocean is estimated from the largest scales to a short-wavelength cutoff of about 6700 km for the period July through September, 1978. The data base consisted of the time-averaged sea-surface topography determined by Seasat and geoid estimates made at the Goddard Space Flight Center. The issues are those of accuracy and resolution. Use of the altimetric surface as a geoid estimate beyond the short-wavelength cutoff reduces the spectral leakage in the estimated dynamic topography from erroneous small-scale geoid estimates without contaminating the low wavenumbers. Comparison of the result with a similarly filtered version of Levitus' (1982) historical average dynamic topography shows good qualitative agreement. There is quantitative disagreement, but it is within the estimated errors of both methods of calculation.

  10. Micron Accurate Absolute Ranging System: Range Extension

    NASA Technical Reports Server (NTRS)

    Smalley, Larry L.; Smith, Kely L.

    1999-01-01

    The purpose of this research is to investigate Fresnel diffraction as a means of obtaining absolute distance measurements with micron or greater accuracy. It is believed that such a system would prove useful to the Next Generation Space Telescope (NGST) as a non-intrusive, non-contact measuring system for use with secondary concentrator station-keeping systems. The present research attempts to validate past experiments and develop ways to apply the phenomena of Fresnel diffraction to micron accurate measurement. This report discusses past research on the phenomena, and the basis of the use Fresnel diffraction distance metrology. The apparatus used in the recent investigations, experimental procedures used, preliminary results are discussed in detail. Continued research and equipment requirements on the extension of the effective range of the Fresnel diffraction systems is also described.

  11. Absolute measurements of fast neutrons using yttrium.

    PubMed

    Roshan, M V; Springham, S V; Rawat, R S; Lee, P; Krishnan, M

    2010-08-01

    Yttrium is presented as an absolute neutron detector for pulsed neutron sources. It has high sensitivity for detecting fast neutrons. Yttrium has the property of generating a monoenergetic secondary radiation in the form of a 909 keV gamma-ray caused by inelastic neutron interaction. It was calibrated numerically using MCNPX and does not need periodic recalibration. The total yttrium efficiency for detecting 2.45 MeV neutrons was determined to be f(n) approximately 4.1x10(-4) with an uncertainty of about 0.27%. The yttrium detector was employed in the NX2 plasma focus experiments and showed the neutron yield of the order of 10(8) neutrons per discharge.

  12. MARQUIS: A Multiplex Method for Absolute Quantification of Peptides and Post-Translational Modifications

    PubMed Central

    Curran, Timothy G; Zhang, Yi; Ma, Daniel J.; Sarkaria, Jann N.; White, Forest M

    2014-01-01

    Absolute quantification of protein expression and post-translational modifications by mass spectrometry has been challenging due to a variety of factors, including the potentially large dynamic range of phosphorylation response. To address these issues, we have developed MARQUIS — Multiplex Absolute Regressed Quantification with Internal Standards — a novel mass spectrometry-based approach using a combination of isobaric tags and heavy-labeled standard peptides to construct internal standard curves for peptides derived from key nodes in signal transduction networks. We applied MARQUIS to quantify phosphorylation dynamics within the EGFR network at multiple time points following stimulation with several ligands, enabling a quantitative comparison of EGFR phosphorylation sites and demonstrating that receptor phosphorylation is qualitatively similar but quantitatively distinct for each EGFR ligand tested. MARQUIS was also applied to quantify the effect of EGFR kinase inhibition on glioblastoma patient derived xenografts. MARQUIS is a versatile method, broadly applicable and extendable to multiple mass spectrometric platforms. PMID:25581283

  13. Developing absolute shock wave equation of state measurements on the NIF

    NASA Astrophysics Data System (ADS)

    Celliers, Peter; Fratanduono, D. E.; Lazicki, A.; London, R. A.; Brygoo, S.; Swift, D. C.; Coppari, F.; Millot, M.; Peterson, J. L.; Meezan, N. B.; Fernandez-Panella, A.; Erskine, D. J.; Ali, S.; Collins, G. W.

    2016-10-01

    The National Ignition Facility provides an unprecedented capability to generate ultra-high pressure planar shock waves (around 10 TPa) in solid samples. We are currently fielding impedance match equation of state (EOS) experiments to determine the shock Hugoniot of various samples relative to EOS standards, such as aluminum and quartz. However, the equations of state of the standards at multi-TPa shock pressures are not yet well-established. Absolute techniques are needed to provide the data needed to establish the Hugoniots of the standards, and also to measure the state of a sample directly. We are pursuing several approaches using absolute techniques. These approaches will be discussed. This work was performed under the auspices of the U.S. Department of Energy by LLNL under contract DE-AC52-07NA27344.

  14. Measured and modelled absolute gravity in Greenland

    NASA Astrophysics Data System (ADS)

    Nielsen, E.; Forsberg, R.; Strykowski, G.

    2012-12-01

    Present day changes in the ice volume in glaciated areas like Greenland will change the load on the Earth and to this change the lithosphere will respond elastically. The Earth also responds to changes in the ice volume over a millennial time scale. This response is due to the viscous properties of the mantle and is known as Glaical Isostatic Adjustment (GIA). Both signals are present in GPS and absolute gravity (AG) measurements and they will give an uncertainty in mass balance estimates calculated from these data types. It is possible to separate the two signals if both gravity and Global Positioning System (GPS) time series are available. DTU Space acquired an A10 absolute gravimeter in 2008. One purpose of this instrument is to establish AG time series in Greenland and the first measurements were conducted in 2009. Since then are 18 different Greenland GPS Network (GNET) stations visited and six of these are visited more then once. The gravity signal consists of three signals; the elastic signal, the viscous signal and the direct attraction from the ice masses. All of these signals can be modelled using various techniques. The viscous signal is modelled by solving the Sea Level Equation with an appropriate ice history and Earth model. The free code SELEN is used for this. The elastic signal is modelled as a convolution of the elastic Greens function for gravity and a model of present day ice mass changes. The direct attraction is the same as the Newtonian attraction and is calculated as this. Here we will present the preliminary results of the AG measurements in Greenland. We will also present modelled estimates of the direct attraction, the elastic and the viscous signals.

  15. Absolute bioavailability of quinine formulations in Nigeria.

    PubMed

    Babalola, C P; Bolaji, O O; Ogunbona, F A; Ezeomah, E

    2004-09-01

    This study compared the absolute bioavailability of quinine sulphate as capsule and as tablet against the intravenous (i.v.) infusion of the drug in twelve male volunteers. Six of the volunteers received intravenous infusion over 4 h as well as the capsule formulation of the drug in a cross-over manner, while the other six received the tablet formulation. Blood samples were taken at predetermined time intervals and plasma analysed for quinine (QN) using reversed-phase HPLC method. QN was rapidly absorbed after the two oral formulations with average t(max) of 2.67 h for both capsule and tablet. The mean elimination half-life of QN from the i.v. and oral dosage forms varied between 10 and 13.5 hr and were not statistically different (P > 0.05). On the contrary, the maximum plasma concentration (C(max)) and area under the curve (AUC) from capsule were comparable to those from i.v. (P > 0.05), while these values were markedly higher than values from tablet formulation (P < 0.05). The therapeutic QN plasma levels were not achieved with the tablet formulation. The absolute bioavailability (F) were 73% (C.l., 53.3 - 92.4%) and 39 % (C.I., 21.7 - 56.6%) for the capsule and tablet respectively and the difference was significant (P < 0.05). The subtherapeutic levels obtained from the tablet form used in this study may cause treatment failure during malaria and caution should be taken when predictions are made from results obtained from different formulations of QN.

  16. Absolute GPS Positioning Using Genetic Algorithms

    NASA Astrophysics Data System (ADS)

    Ramillien, G.

    A new inverse approach for restoring the absolute coordinates of a ground -based station from three or four observed GPS pseudo-ranges is proposed. This stochastic method is based on simulations of natural evolution named genetic algorithms (GA). These iterative procedures provide fairly good and robust estimates of the absolute positions in the Earth's geocentric reference system. For comparison/validation, GA results are compared to the ones obtained using the classical linearized least-square scheme for the determination of the XYZ location proposed by Bancroft (1985) which is strongly limited by the number of available observations (i.e. here, the number of input pseudo-ranges must be four). The r.m.s. accuracy of the non -linear cost function reached by this latter method is typically ~10-4 m2 corresponding to ~300-500-m accuracies for each geocentric coordinate. However, GA can provide more acceptable solutions (r.m.s. errors < 10-5 m2), even when only three instantaneous pseudo-ranges are used, such as a lost of lock during a GPS survey. Tuned GA parameters used in different simulations are N=1000 starting individuals, as well as Pc=60-70% and Pm=30-40% for the crossover probability and mutation rate, respectively. Statistical tests on the ability of GA to recover acceptable coordinates in presence of important levels of noise are made simulating nearly 3000 random samples of erroneous pseudo-ranges. Here, two main sources of measurement errors are considered in the inversion: (1) typical satellite-clock errors and/or 300-metre variance atmospheric delays, and (2) Geometrical Dilution of Precision (GDOP) due to the particular GPS satellite configuration at the time of acquisition. Extracting valuable information and even from low-quality starting range observations, GA offer an interesting alternative for high -precision GPS positioning.

  17. Magnetic Elements at Finite Temperature and Large Deviation Theory

    NASA Astrophysics Data System (ADS)

    Kohn, R. V.; Reznikoff, M. G.; vanden-Eijnden, E.

    2005-08-01

    We investigate thermally activated phenomena in micromagnetics using large deviation theory and concepts from stochastic resonance. We give a natural mathematical definition of finite-temperature astroids, finite-temperature hysteresis loops, etc. Generically, these objects emerge when the (generalized) Arrhenius timescale governing the thermally activated barrier crossing event of magnetic switching matches the timescale at which the magnetic element is pulsed or ramped by an external field; in the special and physically relevant case of multiple-pulse experiments, on the other hand, short-time switching can lead to non-Arrhenius behavior. We show how large deviation theory can be used to explain some properties of the astroids, like their shrinking and sharpening as the number of applied pulses is increased. We also investigate the influence of the dynamics, in particular the relative importance of the gyromagnetic and the damping terms. Finally, we discuss some issues and open questions regarding spatially nonuniform magnetization.

  18. Monitoring of barite sag important in deviated drilling

    SciTech Connect

    Saasen, A.; Marken, C.; Sterri, N. ); Jakobsen, J. )

    1991-08-26

    Very low shear rate and oscillation rheometry techniques provide insight into the properties of drilling fluids that are associated with barite sag observed during drilling operations. This paper provides detailed study of the rheological behavior of four field muds completed with a controlled-stress rheometer. The techniques verified that detailed rheological studies of muds are needed to explain barite sag. Barite sag can be the source of severe drilling and well control problems during the drilling of deviated wells. In a deviated well this phenomenon results from the gravitationally induced settling of the barite to form either a density gradient or a barite sedimentation bed. Barite sag results if the rheological properties of the drilling fluid are inadequate to keep the weighting agent suspended. Improved rheological characterization of drilling fluids leads to a better understanding of barite sag and to the improvement of fluid properties that prevent sag.

  19. Deviations from liquidlike behavior in molten polymer films at interfaces.

    PubMed

    Seo, Young-Soo; Koga, T; Sokolov, J; Rafailovich, M H; Tolan, M; Sinha, S

    2005-04-22

    We have performed x-ray specular and diffuse scattering on liquid polymer films and analyzed the spectra as a function of film thickness and molecular weight. The results show that films whose molecular weight is close to the entanglement length behave as simple liquids except that the shortest wavelength is determined by the radius of gyration (R(g)) rather than the monomer-monomer distance. When the molecular weight is higher than the entanglement length, the strong deviations from liquidlike behavior are observed. We find that the long wavelength cutoff vector, q(l,c), scales with film thickness, d as d(-1.1+/-0.1) rather than the usual d(-2) expected for simple liquids. If we assume that these deviations are due to surface pinning of the polymer chains, then our results are consistent with the formalism developed by Fredrickson et al. to explain the capillary wave spectrum that can propagate in a polymer brush.

  20. Contiguous Uniform Deviation for Multiple Linear Regression in Pattern Recognition

    NASA Astrophysics Data System (ADS)

    Andriana, A. S.; Prihatmanto, D.; Hidaya, E. M. I.; Supriana, I.; Machbub, C.

    2017-01-01

    Understanding images by recognizing its objects is still a challenging task. Face elements detection has been developed by researchers but not yet shows enough information (low resolution in information) needed for recognizing objects. Available face recognition methods still have error in classification and need a huge amount of examples which may still be incomplete. Another approach which is still rare in understanding images uses pattern structures or syntactic grammars describing shape detail features. Image pixel values are also processed as signal patterns which are approximated by mathematical function curve fitting. This paper attempts to add contiguous uniform deviation method to curve fitting algorithm to increase applicability in image recognition system related to object movement. The combination of multiple linear regression and contiguous uniform deviation method are applied to the function of image pixel values, and show results in higher resolution (more information) of visual object detail description in object movement.