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Sample records for absorbed-dose energy dependence

  1. Linear energy transfer dependence of a normoxic polymer gel dosimeter investigated using proton beam absorbed dose measurements

    NASA Astrophysics Data System (ADS)

    Gustavsson, Helen; Bäck, Sven Å. J.; Medin, Joakim; Grusell, Erik; Olsson, Lars E.

    2004-09-01

    Three-dimensional dosimetry with good spatial resolution can be performed using polymer gel dosimetry, which has been investigated for dosimetry of different types of particles. However, there are only sparse data concerning the influence of the linear energy transfer (LET) properties of the radiation on the gel absorbed dose response. The purpose of this study was to investigate possible LET dependence for a polymer gel dosimeter using proton beam absorbed dose measurements. Polymer gel containing the antioxidant tetrakis(hydroxymethyl)phosphonium (THP) was irradiated with 133 MeV monoenergetic protons, and the gel absorbed dose response was evaluated using MRI. The LET distribution for a monoenergetic proton beam was calculated as a function of depth using the Monte Carlo code PETRA. There was a steep increase in the Monte Carlo calculated LET starting at the depth corresponding to the front edge of the Bragg peak. This increase was closely followed by a decrease in the relative detector sensitivity (Srel = Dgel/Ddiode), indicating that the response of the polymer gel detector was dependent on LET. The relative sensitivity was 0.8 at the Bragg peak, and reached its minimum value at the end of the proton range. No significant effects in the detector response were observed for LET < 4.9 keV µm-1, thus indicating that the behaviour of the polymer gel dosimeter would not be altered for the range of LET values expected in the case of photons or electrons in a clinical range of energies.

  2. Angular absorbed dose dependence of internal radiation-generating devices in radiotherapy.

    PubMed

    Bevelacqua, J J

    2012-01-01

    The angular dependence of the absorbed dose from internal radiation-generating devices located within a tumor mass is investigated. Given the systematics of proton and heavy-ion differential scattering cross sections, candidate internal radiation-generating devices will have a relatively constant absorbed dose output beyond a critical angle. Inside this angle, the absorbed dose output is suppressed because elastic and inelastic differential cross sections are peaked in the beam direction. This peaking increases in severity as the particle energy increases and suggests internal radiation-generating devices must have a limited rotation capability to compensate for the depression in the absorbed dose for angles near the beam direction.

  3. Neutron absorbed dose determination by calculations of recoil energy.

    PubMed

    Wrobel, F; Benabdesselam, M; Iacconi, P; Lapraz, D

    2004-01-01

    The aim of this work is to calculate the absorbed dose to matter due to neutrons in the 5-150 MeV energy range. Materials involved in the calculations are Al2O3, CaSO4 and CaS, which may be used as dosemeters and have already been studied for their luminescent properties. The absorbed dose is assumed to be mainly due to the energy deposited by the recoils. Elastic reactions are treated with the ECIS code while for the non-elastic ones, a Monte Carlo code has been developed and allowed to follow the nucleus decay and to determine its characteristics (nature and energy). Finally, the calculations show that the absorbed dose is mainly due to non-elastic process and that above 20 MeV this dose decreases slightly with the neutron energy. PMID:15353750

  4. Simultaneous measurements of absorbed dose and linear energy transfer in therapeutic proton beams.

    PubMed

    Granville, Dal A; Sahoo, Narayan; Sawakuchi, Gabriel O

    2016-02-21

    The biological response resulting from proton therapy depends on both the absorbed dose in the irradiated tissue and the linear energy transfer (LET) of the beam. Currently, optimization of proton therapy treatment plans is based only on absorbed dose. However, recent advances in proton therapy delivery have made it possible to vary the LET distribution for potential therapeutic gain, leading to investigations of using LET as an additional parameter in plan optimization. Having a method to measure and verify both absorbed dose and LET as part of a quality assurance program would be ideal for the safe delivery of such plans. Here we demonstrated the potential of an optically stimulated luminescence (OSL) technique to simultaneously measure absorbed dose and LET. We calibrated the ratio of ultraviolet (UV) to blue emission intensities from Al2O3:C OSL detectors as a function of LET to facilitate LET measurements. We also calibrated the intensity of the blue OSL emission for absorbed dose measurements and introduced a technique to correct for the LET-dependent dose response of OSL detectors exposed to therapeutic proton beams. We demonstrated the potential of our OSL technique by using it to measure LET and absorbed dose under new irradiation conditions, including patient-specific proton therapy treatment plans. In the beams investigated, we found the OSL technique to measure dose-weighted LET within 7.9% of Monte Carlo-simulated values and absorbed dose within 2.5% of ionization chamber measurements.

  5. Simultaneous measurements of absorbed dose and linear energy transfer in therapeutic proton beams.

    PubMed

    Granville, Dal A; Sahoo, Narayan; Sawakuchi, Gabriel O

    2016-02-21

    The biological response resulting from proton therapy depends on both the absorbed dose in the irradiated tissue and the linear energy transfer (LET) of the beam. Currently, optimization of proton therapy treatment plans is based only on absorbed dose. However, recent advances in proton therapy delivery have made it possible to vary the LET distribution for potential therapeutic gain, leading to investigations of using LET as an additional parameter in plan optimization. Having a method to measure and verify both absorbed dose and LET as part of a quality assurance program would be ideal for the safe delivery of such plans. Here we demonstrated the potential of an optically stimulated luminescence (OSL) technique to simultaneously measure absorbed dose and LET. We calibrated the ratio of ultraviolet (UV) to blue emission intensities from Al2O3:C OSL detectors as a function of LET to facilitate LET measurements. We also calibrated the intensity of the blue OSL emission for absorbed dose measurements and introduced a technique to correct for the LET-dependent dose response of OSL detectors exposed to therapeutic proton beams. We demonstrated the potential of our OSL technique by using it to measure LET and absorbed dose under new irradiation conditions, including patient-specific proton therapy treatment plans. In the beams investigated, we found the OSL technique to measure dose-weighted LET within 7.9% of Monte Carlo-simulated values and absorbed dose within 2.5% of ionization chamber measurements. PMID:26859539

  6. Depth dependence of absorbed dose, dose equivalent and linear energy transfer spectra of galactic and trapped particles in polyethylene and comparison with calculations of models

    NASA Technical Reports Server (NTRS)

    Badhwar, G. D.; Cucinotta, F. A.; Wilson, J. W. (Principal Investigator)

    1998-01-01

    A matched set of five tissue-equivalent proportional counters (TEPCs), embedded at the centers of 0 (bare), 3, 5, 8 and 12-inch-diameter polyethylene spheres, were flown on the Shuttle flight STS-81 (inclination 51.65 degrees, altitude approximately 400 km). The data obtained were separated into contributions from trapped protons and galactic cosmic radiation (GCR). From the measured linear energy transfer (LET) spectra, the absorbed dose and dose-equivalent rates were calculated. The results were compared to calculations made with the radiation transport model HZETRN/NUCFRG2, using the GCR free-space spectra, orbit-averaged geomagnetic transmission function and Shuttle shielding distributions. The comparison shows that the model fits the dose rates to a root mean square (rms) error of 5%, and dose-equivalent rates to an rms error of 10%. Fairly good agreement between the LET spectra was found; however, differences are seen at both low and high LET. These differences can be understood as due to the combined effects of chord-length variation and detector response function. These results rule out a number of radiation transport/nuclear fragmentation models. Similar comparisons of trapped-proton dose rates were made between calculations made with the proton transport model BRYNTRN using the AP-8 MIN trapped-proton model and Shuttle shielding distributions. The predictions of absorbed dose and dose-equivalent rates are fairly good. However, the prediction of the LET spectra below approximately 30 keV/microm shows the need to improve the AP-8 model. These results have strong implications for shielding requirements for an interplanetary manned mission.

  7. Determination of the absorbed dose and the average LET of space radiation in dependence on shielding conditions.

    PubMed

    Vana, N; Schoner, W; Noll, M; Fugger, M; Akatov, Y; Shurshakov, V

    1999-01-01

    The HTR method, developed for determination of absorbed dose and average LET of mixed radiation fields in space, was applied during several space missions on space station MIR, space shuttles and satellites. The method utilises the changes of peak height ratios in the glow curves in dependence on the linear energy transfer LET. Due to the small size of the dosemeters the evaluation of the variation of absorbed dose and average LET in dependence on the position of the dosemeters inside the space station is possible. The dose and LET distribution was determined during the experiment ADLET where dosemeters were exposed in two positions with different shielding conditions and during two following experiments (MIR-95, MIR-96) using six positions inside the space station. The results were compared with the shielding conditions of the positions. Calculations of the absorbed dose were carried out for comparison. Results have shown that the average LET increases with increasing absorbing thickness while the absorbed dose decreases.

  8. Calculation of the absorbed dose and dose equivalent induced by medium energy neutrons and protons and comparison with experiment

    NASA Technical Reports Server (NTRS)

    Armstrong, T. W.; Bishop, B. L.

    1972-01-01

    Monte Carlo calculations have been carried out to determine the absorbed dose and dose equivalent for 592-MeV protons incident on a cylindrical phantom and for neutrons from 580-MeV proton-Be collisions incident on a semi-infinite phantom. For both configurations, the calculated depth dependence of the absorbed dose is in good agreement with experimental data.

  9. Diamond detector in absorbed dose measurements in high-energy linear accelerator photon and electron beams.

    PubMed

    Ravichandran, Ramamoorthy; Binukumar, John Pichy; Al Amri, Iqbal; Davis, Cheriyathmanjiyil Antony

    2016-01-01

    Diamond detectors (DD) are preferred in small field dosimetry of radiation beams because of small dose profile penumbras, better spatial resolution, and tissue-equivalent properties. We investigated a commercially available 'microdiamond' detector in realizing absorbed dose from first principles. A microdiamond detector, type TM 60019 with tandem electrometer is used to measure absorbed doses in water, nylon, and PMMA phantoms. With sensitive volume 0.004 mm3, radius 1.1mm, thickness 1 x10(-3) mm, the nominal response is 1 nC/Gy. It is assumed that the diamond detector could collect total electric charge (nC) developed during irradiation at 0 V bias. We found that dose rate effect is less than 0.7% for changing dose rate by 500 MU/min. The reproducibility in obtaining readings with diamond detector is found to be ± 0.17% (1 SD) (n = 11). The measured absorbed doses for 6 MV and 15 MV photons arrived at using mass energy absorption coefficients and stop-ping power ratios compared well with Nd, water calibrated ion chamber measured absorbed doses within 3% in water, PMMA, and nylon media. The calibration factor obtained for diamond detector confirmed response variation is due to sensitivity due to difference in manufacturing process. For electron beams, we had to apply ratio of electron densities of water to carbon. Our results qualify diamond dosimeter as a transfer standard, based on long-term stability and reproducibility. Based on micro-dimensions, we recommend these detectors for pretreatment dose verifications in small field irradiations like stereotactic treatments with image guidance. PMID:27074452

  10. Relative Efficiency of TLD-100 to Linear Energy Transfer Radiation: Correction to Astronaut Absorbed Dose

    NASA Technical Reports Server (NTRS)

    Badhwar, Gautam D.; Cash, B. L.; Semones, E. J.; Yasuda, H.; Fujitaka, K.

    1999-01-01

    Response of thermoluminescent detectors (TLD-100) to high linear energy transfer (LET) particles has been studied using helium, carbon, silicon, and iron ions from the Heavy Ion Medical Accelerator at Chiba (Japan), iron ions from the Brookhaven National Laboratory (NY) Alternate Gradient Synchrotron, and 53, 134, 185, and 232 MeV protons from the Loma Linda accelerator. Using the measured relative (to (137)Cs dose efficiency, and measured LET spectra from a tissue equivalent proportional counter (TEPC) on 20 Space Shuttle flights, and 7 Mir flights, the underestimation of absorbed dose by these detectors has been evaluated. The dose underestimation is between 15-20% depending upon the flight inclination and shielding location. This has been confirmed by direct correlation of measured dose by TEPC and TLD-100 at a low shielded location in the Shuttle mid-deck. A comparison of efficiency- LET data with a compilation of similar data from TLD-700, shows that shapes of the two curves are nearly identical, but that the TLD-100 curve is systematically lower by about 13%, and is the major cause of dose underestimation. These results strongly suggest that TLDs used for crew dose estimation be regularly calibrated using heavy ions.

  11. Relative Efficiency of TLD-100 to High Linear Energy Transfer Radiation: Correction to Astronaut Absorbed Dose

    NASA Technical Reports Server (NTRS)

    Badhwar, G. D.; Cash, B. L.; Semones, E. J.; Yasuda, H.; Fujitaka, K.

    1999-01-01

    Response of thermoluminescent detectors (TLD-100) to high linear energy transfer (LET) particles has been studied using helium, carbon, silicon, and iron ions from the Heavy Ion Medical Accelerator at Chiba (Japan), iron ions from the Brookhaven National Laboratory (NY) Alternate Gradient Synchrotron, and 53, 134, 185, and 232 MeV protons from the Loma Linda accelerator. Using the measured relative (to 137Cs) dose efficiency, and measured LET spectra from a tissue equivalent proportional counter (TEPC) on 20 Space Shuttle flights, and 7 Mir flights, the underestimation of absorbed dose by these detectors has been evaluated. The dose underestimation is between 15-20% depending upon the flight inclination and shielding location. This has been confirmed by direct correlation of measured dose by TEPC and TLD-100 at a low shielded location in the Shuttle mid-deck. A comparison of efficiency- LET data with a compilation of similar data from TLD-700, shows that shapes of the two curves are nearly identical, but that the TLD-100 curve is systematically lower by about 13%, and is the major cause of dose underestimation. These results strongly suggest that TLDs used for crew dose estimation be regularly calibrated using heavy ions.

  12. Dependence of TLD thermoluminescence yield on absorbed dose in a thermal neutron field.

    PubMed

    Gambarini, G; Roy, M S

    1997-01-01

    The emission from 6LiF and 7LiF thermoluminescence dosimeters (TLDs) exposed to the mixed field of thermal neutrons and gamma-rays of the thermal facility of a TRIGA MARK II nuclear reactor has been investigated for various thermal neutron fluences of the order of magnitude of those utilised in radiotherapy, with the purpose of investigating the reliability of TLD readouts in such radiation fields and of giving some information for better obtainment of the absorbed dose values. The emission after exposure in this mixed field is compared with the emission after gamma-rays only. The glow curves have been deconvoluted into gaussian peaks, and the differences in the characteristics of the peaks observed for the two radiation fields, having different linear energy transfers, and for different doses are shown. Irreversible radiation damage in dosimeters having high sensitivity to thermal neutrons is also reported, showing a memory effect of the previous thermal neutron irradiation history which is not restored by anneal treatment. PMID:9463872

  13. A graphite calorimeter for absolute measurements of absorbed dose to water: application in medium-energy x-ray filtered beams

    NASA Astrophysics Data System (ADS)

    Pinto, M.; Pimpinella, M.; Quini, M.; D'Arienzo, M.; Astefanoaei, I.; Loreti, S.; Guerra, A. S.

    2016-02-01

    The Italian National Institute of Ionizing Radiation Metrology (ENEA-INMRI) has designed and built a graphite calorimeter that, in a water phantom, has allowed the determination of the absorbed dose to water in medium-energy x-rays with generating voltages from 180 to 250 kV. The new standard is a miniaturized three-bodies calorimeter, with a disc-shaped core of 21 mm diameter and 2 mm thickness weighing 1.134 g, sealed in a PMMA waterproof envelope with air-evacuated gaps. The measured absorbed dose to graphite is converted into absorbed dose to water by means of an energy-dependent conversion factor obtained from Monte Carlo simulations. Heat-transfer correction factors were determined by FEM calculations. At a source-to-detector distance of 100 cm, a depth in water of 2 g cm-2, and at a dose rate of about 0.15 Gy min-1, results of calorimetric measurements of absorbed dose to water, D w, were compared to experimental determinations, D wK, obtained via an ionization chamber calibrated in terms of air kerma, according to established dosimetry protocols. The combined standard uncertainty of D w and D wK were estimated as 1.9% and 1.7%, respectively. The two absorbed dose to water determinations were in agreement within 1%, well below the stated measurement uncertainties. Advancements are in progress to extend the measurement capability of the new in-water-phantom graphite calorimeter to other filtered medium-energy x-ray qualities and to reduce the D w uncertainty to around 1%. The new calorimeter represents the first implementation of in-water-phantom graphite calorimetry in the kilovoltage range and, allowing independent determinations of D w, it will contribute to establish a robust system of absorbed dose to water primary standards for medium-energy x-ray beams.

  14. Determination of absorbed dose to water around a clinical HDR {sup 192}Ir source using LiF:Mg,Ti TLDs demonstrates an LET dependence of detector response

    SciTech Connect

    Carlsson Tedgren, Aasa; Elia, Rouba; Hedtjaern, Haakan; Olsson, Sara; Alm Carlsson, Gudrun

    2012-02-15

    LiF:Mg,Ti TLDs and the EPR lithium formate dosimeters was, however, statistically significant and in agreement with the difference in relative detector responses found for the two detector systems by Carlsson Tedgren et al. [Med. Phys. 38, 5539-5550 (2011)] and by Adolfsson et al.[Med. Phys. 37, 4946-4959 (2010)]. Conclusions: When calibrated in {sup 60}Co or MV photon beams, correction for the linear energy transfer (LET) dependence of LiF:Mg,Ti detector response will be needed as to measure absorbed doses to water in a {sup 192}Ir beam with highest accuracy. Such corrections will depend on the manufacturing process (MTS-N Poland or Harshaw TLD-100) and details of the annealing and read-out schemes used.

  15. A graphite calorimeter for absolute measurements of absorbed dose to water: application in medium-energy x-ray filtered beams.

    PubMed

    Pinto, M; Pimpinella, M; Quini, M; D'Arienzo, M; Astefanoaei, I; Loreti, S; Guerra, A S

    2016-02-21

    The Italian National Institute of Ionizing Radiation Metrology (ENEA-INMRI) has designed and built a graphite calorimeter that, in a water phantom, has allowed the determination of the absorbed dose to water in medium-energy x-rays with generating voltages from 180 to 250 kV. The new standard is a miniaturized three-bodies calorimeter, with a disc-shaped core of 21 mm diameter and 2 mm thickness weighing 1.134 g, sealed in a PMMA waterproof envelope with air-evacuated gaps. The measured absorbed dose to graphite is converted into absorbed dose to water by means of an energy-dependent conversion factor obtained from Monte Carlo simulations. Heat-transfer correction factors were determined by FEM calculations. At a source-to-detector distance of 100 cm, a depth in water of 2 g cm(-2), and at a dose rate of about 0.15 Gy min(-1), results of calorimetric measurements of absorbed dose to water, D(w), were compared to experimental determinations, D wK, obtained via an ionization chamber calibrated in terms of air kerma, according to established dosimetry protocols. The combined standard uncertainty of D(w) and D(wK) were estimated as 1.9% and 1.7%, respectively. The two absorbed dose to water determinations were in agreement within 1%, well below the stated measurement uncertainties. Advancements are in progress to extend the measurement capability of the new in-water-phantom graphite calorimeter to other filtered medium-energy x-ray qualities and to reduce the D(w) uncertainty to around 1%. The new calorimeter represents the first implementation of in-water-phantom graphite calorimetry in the kilovoltage range and, allowing independent determinations of D(w), it will contribute to establish a robust system of absorbed dose to water primary standards for medium-energy x-ray beams. PMID:26841127

  16. Monte Carlo evaluations of the absorbed dose and quality dependence of Al{sub 2}O{sub 3} in radiotherapy photon beams

    SciTech Connect

    Chen Shaowen; Wang Xuetao; Chen Lixin; Tang Qiang; Liu Xiaowei

    2009-10-15

    Purpose: The purpose of this work was to evaluate the absorbed dose to Al{sub 2}O{sub 3} dosimeter at various depths of water phantom in radiotherapy photon beams by Monte Carlo simulation and evaluate the beam quality dependence. Methods: The simulations were done using EGSnrc. The cylindrical Al{sub 2}O{sub 3} dosimeter ({Phi}4 mmx1 mm) was placed at the central axis of the water phantom ({Phi}16 cmx16 cm) at depths between 0.5 and 8 cm. The incident beams included monoenergetic photon beams ranging from 1 to 18 MeV, {sup 60}Co {gamma} beams, Varian 6 MV beams using phase space files based on a full simulation of the linac, and Varian beams between 4 and 24 MV using Mohan's spectra. The absorbed dose to the dosimeter and the water at the corresponding position in the absence of the dosimeter, as well as absorbed dose ratio factor f{sub md}, was calculated. Results: The results show that f{sub md} depends obviously on the photon energy at the shallow depths. However, as the depth increases, the change in f{sub md} becomes small, beyond the buildup region, the maximum discrepancy of f{sub md} to the average value is not more than 1%. Conclusions: These simulation results confirm the use of Al{sub 2}O{sub 3} dosimeter in radiotherapy photon beams and clearly indicate that more attention should be paid when using such a dosimeter in the buildup region of high-energy radiotherapy photon beams.

  17. Absorbed doses and energy imparted from radiographic examination of velopharyngeal function during speech

    SciTech Connect

    Isberg, A.; Julin, P.; Kraepelien, T.; Henrikson, C.O. )

    1989-04-01

    Absorbed doses of radiation were measured by thermoluminescent dosimeters (TLDs) using a skull phantom during simulated cinefluorographic and videofluorographic examination of velopharyngeal function in frontal and lateral projections. Dosages to the thyroid gland, the parotid gland, the pituitary gland, and ocular lens were measured. Radiation dosage was found to be approximately 10 times less for videofluoroscopy when compared with that of cinefluoroscopy. In addition, precautionary measures were found to reduce further the exposure of radiation-sensitive tissues. Head fixation and shielding resulted in dose reduction for both video- and cinefluoroscopy. Pulsing exposure for cinefluoroscopy also reduced the dosage.

  18. PHITS simulations of absorbed dose out-of-field and neutron energy spectra for ELEKTA SL25 medical linear accelerator

    NASA Astrophysics Data System (ADS)

    Puchalska, Monika; Sihver, Lembit

    2015-06-01

    Monte Carlo (MC) based calculation methods for modeling photon and particle transport, have several potential applications in radiotherapy. An essential requirement for successful radiation therapy is that the discrepancies between dose distributions calculated at the treatment planning stage and those delivered to the patient are minimized. It is also essential to minimize the dose to radiosensitive and critical organs. With MC technique, the dose distributions from both the primary and scattered photons can be calculated. The out-of-field radiation doses are of particular concern when high energy photons are used, since then neutrons are produced both in the accelerator head and inside the patients. Using MC technique, the created photons and particles can be followed and the transport and energy deposition in all the tissues of the patient can be estimated. This is of great importance during pediatric treatments when minimizing the risk for normal healthy tissue, e.g. secondary cancer. The purpose of this work was to evaluate 3D general purpose PHITS MC code efficiency as an alternative approach for photon beam specification. In this study, we developed a model of an ELEKTA SL25 accelerator and used the transport code PHITS for calculating the total absorbed dose and the neutron energy spectra infield and outside the treatment field. This model was validated against measurements performed with bubble detector spectrometers and Boner sphere for 18 MV linacs, including both photons and neutrons. The average absolute difference between the calculated and measured absorbed dose for the out-of-field region was around 11%. Taking into account a simplification for simulated geometry, which does not include any potential scattering materials around, the obtained result is very satisfactorily. A good agreement between the simulated and measured neutron energy spectra was observed while comparing to data found in the literature.

  19. PHITS simulations of absorbed dose out-of-field and neutron energy spectra for ELEKTA SL25 medical linear accelerator.

    PubMed

    Puchalska, Monika; Sihver, Lembit

    2015-06-21

    Monte Carlo (MC) based calculation methods for modeling photon and particle transport, have several potential applications in radiotherapy. An essential requirement for successful radiation therapy is that the discrepancies between dose distributions calculated at the treatment planning stage and those delivered to the patient are minimized. It is also essential to minimize the dose to radiosensitive and critical organs. With MC technique, the dose distributions from both the primary and scattered photons can be calculated. The out-of-field radiation doses are of particular concern when high energy photons are used, since then neutrons are produced both in the accelerator head and inside the patients. Using MC technique, the created photons and particles can be followed and the transport and energy deposition in all the tissues of the patient can be estimated. This is of great importance during pediatric treatments when minimizing the risk for normal healthy tissue, e.g. secondary cancer. The purpose of this work was to evaluate 3D general purpose PHITS MC code efficiency as an alternative approach for photon beam specification. In this study, we developed a model of an ELEKTA SL25 accelerator and used the transport code PHITS for calculating the total absorbed dose and the neutron energy spectra infield and outside the treatment field. This model was validated against measurements performed with bubble detector spectrometers and Boner sphere for 18 MV linacs, including both photons and neutrons. The average absolute difference between the calculated and measured absorbed dose for the out-of-field region was around 11%. Taking into account a simplification for simulated geometry, which does not include any potential scattering materials around, the obtained result is very satisfactorily. A good agreement between the simulated and measured neutron energy spectra was observed while comparing to data found in the literature.

  20. Degradation and decoloration of textiles wastewater by electron beam irradiation: Effect of energy, current and absorbed dose

    NASA Astrophysics Data System (ADS)

    Bakar, Khomsaton Abu; Ahmad, Pauzi; Zulkafli, Hashim, Siti A'aisah

    2014-09-01

    In this study, electron beam accelerator (EB) was used to treat textiles wastewater from Rawang Industrial Park, Selangor. The objectives were to determine effective energy, beam current and absorbed dose required for decoloration and degradation of the textiles effluent. The textiles effluent was irradiated in a batch with various energy of 1MeV to 3MeV at constant beam current of 30mA. It was observed that removal of color and COD increases with higher beam energy. The EB energy of 1MeV effectively to removed 58% color and 19% COD. For textile effluent sample irradiated at fix energy of 1MeV and 3Mev but at different beam current 10mA, 20mA and 30mA. It was observed that removal of color and COD increases with the increased of beam current at each energy. However removal of color was significantly better at 1Mev as compared to 3Mev. In the case of textiles effluent, irradiated at doses of 17, 20,25,30, 35, 100 and 200kGy using 30 kW power of EB (1Mev, 30mA), results shows removal of BOD5, COD and color were in the range 9%-33%, 14%-38% and 43%-78% respectively.

  1. Degradation and decoloration of textiles wastewater by electron beam irradiation: Effect of energy, current and absorbed dose

    SciTech Connect

    Bakar, Khomsaton Abu; Zulkafli,; Hashim, Siti A'aisah; Ahmad, Pauzi

    2014-09-03

    In this study, electron beam accelerator (EB) was used to treat textiles wastewater from Rawang Industrial Park, Selangor. The objectives were to determine effective energy, beam current and absorbed dose required for decoloration and degradation of the textiles effluent. The textiles effluent was irradiated in a batch with various energy of 1MeV to 3MeV at constant beam current of 30mA. It was observed that removal of color and COD increases with higher beam energy. The EB energy of 1MeV effectively to removed 58% color and 19% COD. For textile effluent sample irradiated at fix energy of 1MeV and 3Mev but at different beam current 10mA, 20mA and 30mA. It was observed that removal of color and COD increases with the increased of beam current at each energy. However removal of color was significantly better at 1Mev as compared to 3Mev. In the case of textiles effluent, irradiated at doses of 17, 20,25,30, 35, 100 and 200kGy using 30 kW power of EB (1Mev, 30mA), results shows removal of BOD{sub 5}, COD and color were in the range 9%-33%, 14%-38% and 43%-78% respectively.

  2. Absorbed dose water calorimeter

    SciTech Connect

    Domen, S.R.

    1982-01-26

    An absorbed dose water calorimeter that takes advantage of the low thermal diffusivity of water and the water-imperviousness of polyethylene film. An ultra-small bead thermistor is sandwiched between two thin polyethylene films stretched between insulative supports in a water bath. The polyethylene films insulate the thermistor and its leads, the leads being run out from between the films in insulated sleeving and then to junctions to form a wheatstone bridge circuit. Convection barriers may be provided to reduce the effects of convection from the point of measurement. Controlled heating of different levels in the water bath is accomplished by electrical heater circuits provided for controlling temperature drift and providing adiabatic operation of the calorimeter. The absorbed dose is determined from the known specific heat of water and the measured temperature change.

  3. First international comparison of primary absorbed dose to water standards in the medium-energy X-ray range

    NASA Astrophysics Data System (ADS)

    Büermann, Ludwig; Guerra, Antonio Stefano; Pimpinella, Maria; Pinto, Massimo; de Pooter, Jacco; de Prez, Leon; Jansen, Bartel; Denoziere, Marc; Rapp, Benjamin

    2016-01-01

    This report presents the results of the first international comparison of primary measurement standards of absorbed dose to water for the medium-energy X-ray range. Three of the participants (VSL, PTB, LNE-LNHB) used their existing water calorimeter based standards and one participant (ENEA) recently developed a new standard based on a water-graphite calorimeter. The participants calibrated three transfer chambers of the same type in terms of absorbed dose to water (NDw) and in addition in terms of air kerma (NK) using the CCRI radiation qualities in the range 100 kV to 250 kV. The additional NK values were intended to be used for a physical analysis of the ratios NDw/NK. All participants had previously participated in the BIPM.RI(I)-K3 key comparison of air kerma standards. Ratios of pairs of NMI's NK results of the current comparison were found to be consistent with the corresponding key comparison results within the expanded uncertainties of 0.6 % - 1 %. The NDw results were analysed in terms of the degrees of equivalence with the comparison reference values which were calculated for each beam quality as the weighted means of all results. The participant's results were consistent with the reference value within the expanded uncertainties. However, these expanded uncertainties varied significantly and ranged between about 1-1.8 % for the water calorimeter based standards and were estimated at 3.7 % for the water-graphite calorimeter. It was shown previously that the ratios NDw/NK for the type of ionization chamber used as transfer chamber in this comparison were very close (within less than 1 %) to the calculated values of (bar muen/ρ)w,ad, the mean values of the water-to-air ratio of the mass-energy-absorption coefficients at the depth d in water. Some of the participant's results deviated significantly from the expected behavior. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of

  4. Comparison of the NMIJ and the ARPANSA standards for absorbed dose to water in high-energy photon beams.

    PubMed

    Shimizu, M; Morishita, Y; Kato, M; Tanaka, T; Kurosawa, T; Takata, N; Saito, N; Ramanathan, G; Harty, P D; Oliver, C; Wright, T; Butler, D J

    2015-04-01

    The authors report the results of an indirect comparison of the standards of absorbed dose to water in high-energy photon beams from a clinical linac and (60)Co radiation beam performed between the National Metrology Institute of Japan (NMIJ) and the Australian Radiation Protection and Nuclear Safety Agency (ARPANSA). Three ionisation chambers were calibrated by the NMIJ in April and June 2013 and by the ARPANSA in May 2013. The average ratios of the calibration coefficients for the three ionisation chambers obtained by the NMIJ to those obtained by the ARPANSA were 0.9994, 1.0040 and 1.0045 for 6-, 10- and 15-MV (18 MV at the ARPANSA) high-energy photon beams, respectively. The relative standard uncertainty of the value was 7.2 × 10(-3). The ratio for (60)Co radiation was 0.9986(66), which is consistent with the results published in the key comparison of BIPM.RI(I)-K4.

  5. Determination of absorbed dose in high-energy electron and photon radiation by means of an uncalibrated ionization chamber.

    PubMed

    Klevenhagen, S C

    1991-02-01

    The aim of this study was to develop a dosimetric method based on an ionization chamber which has an uncalibrated sensitive volume but which behaves as a Bragg-Gray cavity in high-energy radiation. The new type of chamber developed in the course of this study has a variable volume and is constructed from water-similar materials. It can be used in a water phantom directly in a beam of a therapy megavoltage machine under clinical conditions. The chamber allows absorbed dose to be determined from first principles, overcoming many of the problems encountered with conventional dosimetry based on calibrated chambers. The study involved an intercomparison of the performance of the new chamber in high-energy electron and photon radiation with the conventional calibrated chambers employed according to the established dosimetry protocols. Good agreement was found between these dosimetric methods and it may therefore be concluded that the method developed in this work can be successfully employed for absolute dosimetry. The new chamber is a promising device for research in various aspects of dosimetry.

  6. On the definition of absorbed dose

    NASA Astrophysics Data System (ADS)

    Grusell, Erik

    2015-02-01

    Purpose: The quantity absorbed dose is used extensively in all areas concerning the interaction of ionizing radiation with biological organisms, as well as with matter in general. The most recent and authoritative definition of absorbed dose is given by the International Commission on Radiation Units and Measurements (ICRU) in ICRU Report 85. However, that definition is incomplete. The purpose of the present work is to give a rigorous definition of absorbed dose. Methods: Absorbed dose is defined in terms of the random variable specific energy imparted. A random variable is a mathematical function, and it cannot be defined without specifying its domain of definition which is a probability space. This is not done in report 85 by the ICRU, mentioned above. Results: In the present work a definition of a suitable probability space is given, so that a rigorous definition of absorbed dose is possible. This necessarily includes the specification of the experiment which the probability space describes. In this case this is an irradiation, which is specified by the initial particles released and by the material objects which can interact with the radiation. Some consequences are discussed. Specific energy imparted is defined for a volume, and the definition of absorbed dose as a point function involves the specific energy imparted for a small mass contained in a volume surrounding the point. A possible more precise definition of this volume is suggested and discussed. Conclusions: The importance of absorbed dose motivates a proper definition, and one is given in the present work. No rigorous definition has been presented before.

  7. An Absorbed-Dose/Dose-Rate Dependence for the Alanine-EPR Dosimetry System and Its Implications in High-Dose Ionizing Radiation Metrology

    PubMed Central

    Desrosiers, M. F.; Puhl, J. M.; Cooper, S. L.

    2008-01-01

    NIST developed the alanine dosimetry system in the early 1990s to replace radiochromic dye film dosimeters. Later in the decade the alanine system was firmly established as a transfer service for high-dose radiation dosimetry and an integral part of the internal calibration scheme supporting these services. Over the course of the last decade, routine monitoring of the system revealed a small but significant observation that, after examination, led to the characterization of a previously unknown absorbed-dose-dependent, dose-rate effect for the alanine system. Though the potential impact of this effect is anticipated to be extremely limited for NIST’s customer-based transfer dosimetry service, much greater implications may be realized for international measurement comparisons between National Measurement Institutes. PMID:27096113

  8. The effect of differences in data base on the determination of absorbed dose in high-energy photon beams using the American Association of Physicists in Medicine protocol.

    PubMed

    Mijnheer, B J; Chin, L M

    1989-01-01

    Exposure rates were adjusted at the National Institute of Standards and Technology (NIST) on January 1, 1986 to take into account more recent values for some physical parameters, mainly in electron stopping power ratios. Exposure calibration factors for 60Co gamma rays Nx will therefore be lowered by 1.1%. Consequently, absorbed dose determinations in high-energy photon beams will be reduced by the same amount if the values for these physical parameters remain unchanged in the American Association of Physicists in Medicine (AAPM) protocol. If the same data base as used at NIST is applied in the AAPM protocol, then Ngas/Nx values, water-air stopping power ratios, and Pwall values will be different. The overall change in absorbed dose determinations using a consistent set of data will be a reduction of 0.8% for 60Co gamma rays and 1.5% for a 20-MV x-ray beam compared to the values before January 1, 1986. Since the net effect is small when different sets of data are applied, the new NIST exposure calibration factors may be used in combination with the AAPM protocol without significant error.

  9. TOPICAL REVIEW: Advances in the determination of absorbed dose to water in clinical high-energy photon and electron beams using ionization chambers

    NASA Astrophysics Data System (ADS)

    Saiful Huq, M.; Andreo, Pedro

    2004-02-01

    During the last two decades, absorbed dose to water in clinical photon and electron beams was determined using dosimetry protocols and codes of practice based on radiation metrology standards of air kerma. It is now recommended that clinical reference dosimetry be based on standards of absorbed dose to water. Newer protocols for the dosimetry of radiotherapy beams, based on the use of an ionization chamber calibrated in terms of absorbed dose to water, ND,w, in a standards laboratory's reference quality beam, have been published by several national or regional scientific societies and international organizations. Since the publication of these protocols multiple theoretical and experimental dosimetry comparisons between the various ND,w based recommendations, and between the ND,w and the former air kerma (NK) based protocols, have been published. This paper provides a comprehensive review of the dosimetry protocols based on these standards and of the intercomparisons of the different protocols published in the literature, discussing the reasons for the observed discrepancies between them. A summary of the various types of standards of absorbed dose to water, together with an analysis of the uncertainties along the various steps of the dosimetry chain for the two types of formalism, is also included. It is emphasized that the NK-ND,air and ND,w formalisms have very similar uncertainty when the same criteria are used for both procedures. Arguments are provided in support of the recommendation for a change in reference dosimetry based on standards of absorbed dose to water.

  10. Determination of neutron absorbed doses in lithium aluminates.

    PubMed

    Delfín Loya, A; Carrera, L M; Ureña-Núñez, F; Palacios, O; Bosch, P

    2003-04-01

    Lithium-based ceramics have been proposed as tritium breeders for fusion reactors. The lithium aluminate (gamma phase) seems to be thermally and structurally stable, the damages produced by neutron irradiation depend on the absorbed dose. A method based on the measurement of neutron activation of foils through neutron capture has been developed to obtain the neutron absorbed dose in lithium aluminates irradiated in the thermal column facility and in the fixed irradiation system of a Triga Mark III Nuclear Reactor. PMID:12672632

  11. The absorbed dose to blood from blood-borne activity

    NASA Astrophysics Data System (ADS)

    Hänscheid, H.; Fernández, M.; Lassmann, M.

    2015-01-01

    The radiation absorbed dose to blood and organs from activity in the blood is relevant for nuclear medicine dosimetry and for research in biodosimetry. The present study provides coefficients for the average absorbed dose rates to the blood from blood-borne activity for radionuclides frequently used in targeted radiotherapy and in PET diagnostics. The results were deduced from published data for vessel radius-dependent dose rate coefficients and reasonable assumptions on the blood-volume distribution as a function of the vessel radius. Different parts of the circulatory system were analyzed separately. Vessel size information for heart chambers, aorta, vena cava, pulmonary artery, and capillaries was taken from published results of morphometric measurements. The remaining blood not contained in the mentioned vessels was assumed to reside in fractal-like vascular trees, the smallest branches of which are the arterioles or venules. The applied vessel size distribution is consistent with recommendations of the ICRP on the blood-volume distribution in the human. The resulting average absorbed dose rates to the blood per nuclear disintegration per milliliter (ml) of blood are (in 10-11 Gy·s-1·Bq-1·ml) Y-90: 5.58, I-131: 2.49, Lu-177: 1.72, Sm-153: 2.97, Tc-99m: 0.366, C-11: 4.56, F-18: 3.61, Ga-68: 5.94, I-124: 2.55. Photon radiation contributes 1.1-1.2·10-11 Gy·s-1·Bq-1·ml to the total dose rate for positron emitters but significantly less for the other nuclides. Blood self-absorption of the energy emitted by ß-particles in the whole blood ranges from 37% for Y-90 to 80% for Tc-99m. The correspondent values in vascular trees, which are important for the absorbed dose to organs, range from 30% for Y-90 to 82% for Tc-99m.

  12. Evaluation of lens absorbed dose with Cone Beam IGRT procedures.

    PubMed

    Palomo, R; Pujades, M C; Gimeno-Olmos, J; Carmona, V; Lliso, F; Candela-Juan, C; Vijande, J; Ballester, F; Perez-Calatayud, J

    2015-12-01

    The purpose of this work is to evaluate the absorbed dose to the eye lenses due to the cone beam computed tomography (CBCT) system used to accurately position the patient during head-and-neck image guided procedures. The on-board imaging (OBI) systems (v.1.5) of Clinac iX and TrueBeam (Varian) accelerators were used to evaluate the imparted dose to the eye lenses and some additional points of the head. All CBCT scans were acquired with the Standard-Dose Head protocol from Varian. Doses were measured using thermoluminescence dosimeters (TLDs) placed in an anthropomorphic phantom. TLDs were calibrated at the beam quality used to reduce their energy dependence. Average dose to the lens due to the OBI systems of the Clinac iX and the TrueBeam were 0.71  ±  0.07 mGy/CBCT and 0.70  ±  0.08 mGy/CBCT, respectively. The extra absorbed dose received by the eye lenses due to one CBCT acquisition with the studied protocol is far below the 500 mGy threshold established by ICRP for cataract formation (ICRP 2011 Statement on Tissue Reactions). However, the incremental effect of several CBCT acquisitions during the whole treatment should be taken into account. PMID:26457404

  13. Absorbed dose and LET spectra measurements on LDEF

    NASA Technical Reports Server (NTRS)

    Benton, E. V.; Csige, I.; Frank, A. L.; Benton, E. R.; Frigo, L. A.; Parnell, T. A.; Watts, J.; Harmon, A.

    1995-01-01

    Total absorbed doses measured with TLD's, linear energy transfer (LET) spectra measured with plastic track detectors, and low energy neutrons measured on LDEF have been compared with model calculations. The total absorbed doses measured in TLD's were higher than predicted in the calculations of Armstrong et al. and differ from the calculations of Atwell et al. LDEF LET spectra are dependent on detector orientation, shielding and experiment location. These factors need to be taken into account when modeling the LDEF LET spectra. LET spectra measured with plastic nuclear track detectors (PNTD's) also deviate significantly from calculations especially for high LET particles (LET(sub infinity) H2O greater than 100keV/micron). Modeling efforts to date do not include the contribution of proton induced secondaries. Analysis of polycarbonate PNTD's from the West-side of LDEF has revealed a very high fluence of tracks (greater than 1 x 10(exp 7) tracks/cm(exp 2) under 2 gm/cm(exp 2) shielding). Fluence drops off rapidly as shielding depth increases. Tracks only form in the region of the detector closest to the surface, not in the bulk of the detector. To date no adequate explanation for this observation has been found. We plan to measure range distribution of very high LET (LET (sub infinity) H2O greater than 500 keV/micron) secondary particles produced in silicon wafer by high energy primary cosmic ray particles. Refinements of experimental techniques and model calculations are being carried out in order to understand existing discrepancies between experimental measurements and calculations.

  14. Improved estimates of the radiation absorbed dose to the urinary bladder wall

    NASA Astrophysics Data System (ADS)

    Andersson, Martin; Minarik, David; Johansson, Lennart; Mattsson, Sören; Leide-Svegborn, Sigrid

    2014-05-01

    Specific absorbed fractions (SAFs) have been calculated as a function of the content in the urinary bladder in order to allow more realistic calculations of the absorbed dose to the bladder wall. The SAFs were calculated using the urinary bladder anatomy from the ICRP male and female adult reference computational phantoms. The urinary bladder and its content were approximated by a sphere with a wall of constant mass, where the thickness of the wall depended on the amount of urine in the bladder. SAFs were calculated for males and females with 17 different urinary bladder volumes from 10 to 800 mL, using the Monte Carlo computer program MCNP5, at 25 energies of mono-energetic photons and electrons ranging from 10 KeV to 10 MeV. The decay was assumed to be homogeneously distributed in the urinary bladder content and the urinary bladder wall, and the mean absorbed dose to the urinary bladder wall was calculated. The Monte Carlo simulations were validated against measurements made with thermoluminescent dosimeters. The SAFs obtained for a urine volume of 200 mL were compared to the values calculated for the urinary bladder wall using the adult reference computational phantoms. The mean absorbed dose to the urinary wall from 18F-FDG was found to be 77 µGy/MBq formales and 86 µGy/MBq for females, while for 99mTc-DTPA the mean absorbed doses were 80 µGy/MBq for males and 86 µGy/MBq for females. Compared to calculations using a constant value of the SAF from the adult reference computational phantoms, the mean absorbed doses to the bladder wall were 60% higher for 18F-FDG and 30% higher for 99mTc-DTPA using the new SAFs.

  15. Absorbed dose to water reference dosimetry using solid phantoms in the context of absorbed-dose protocols

    SciTech Connect

    Seuntjens, Jan; Olivares, Marina; Evans, Michael; Podgorsak, Ervin

    2005-09-15

    For reasons of phantom material reproducibility, the absorbed dose protocols of the American Association of Physicists in Medicine (AAPM) (TG-51) and the International Atomic Energy Agency (IAEA) (TRS-398) have made the use of liquid water as a phantom material for reference dosimetry mandatory. In this work we provide a formal framework for the measurement of absorbed dose to water using ionization chambers calibrated in terms of absorbed dose to water but irradiated in solid phantoms. Such a framework is useful when there is a desire to put dose measurements using solid phantoms on an absolute basis. Putting solid phantom measurements on an absolute basis has distinct advantages in verification measurements and quality assurance. We introduce a phantom dose conversion factor that converts a measurement made in a solid phantom and analyzed using an absorbed dose calibration protocol into absorbed dose to water under reference conditions. We provide techniques to measure and calculate the dose transfer from solid phantom to water. For an Exradin A12 ionization chamber, we measured and calculated the phantom dose conversion factor for six Solid Water{sup TM} phantoms and for a single Lucite phantom for photon energies between {sup 60}Co and 18 MV photons. For Solid Water{sup TM} of certified grade, the difference between measured and calculated factors varied between 0.0% and 0.7% with the average dose conversion factor being low by 0.4% compared with the calculation whereas for Lucite, the agreement was within 0.2% for the one phantom examined. The composition of commercial plastic phantoms and their homogeneity may not always be reproducible and consistent with assumed composition. By comparing measured and calculated phantom conversion factors, our work provides methods to verify the consistency of a given plastic for the purpose of clinical reference dosimetry.

  16. A method to efficiently simulate absorbed dose in radio-sensitive instrumentation components

    NASA Astrophysics Data System (ADS)

    Santana Leitner, M.

    2015-12-01

    Components installed in tunnels of high-power accelerators are prone to radiation-induced damage and malfunction. Such machines are usually modeled in detail and the radiation cascades are transported through the three-dimensional models in Monte Carlo codes. Very often those codes are used to compute energy deposition in beam components or radiation fields to the public and the environment. However, sensitive components such as electronic boards or insulator cables are less easily simulated, as their small size makes dose scoring a (statistically) inefficient process. Moreover the process to decide their location is iterative, as in order to define where these will be safely installed, the dose needs to be computed, but to do so the location needs to be known. This note presents a different approach to indirectly asses the potential absorbed dose by certain components when those are installed within a given radiation field. The method consists first in finding the energy and particle-dependent absorbed dose to fluence response function, and then programming those in a radiation transport Monte Carlo code, so that fluences in vacuum/air can be automatically converted real-time into potential absorbed doses and then mapped in the same way as fluences or dose equivalent magnitudes.

  17. Evaluation of absorbed dose in Gadolinium neutron capture therapy

    NASA Astrophysics Data System (ADS)

    Abdullaeva, Gayane; Djuraeva, Gulnara; Kim, Andrey; Koblik, Yuriy; Kulabdullaev, Gairatulla; Rakhmonov, Turdimukhammad; Saytjanov, Shavkat

    2015-02-01

    Gadolinium neutron capture therapy (GdNCT) is used for treatment of radioresistant malignant tumors. The absorbed dose in GdNCT can be divided into four primary dose components: thermal neutron, fast neutron, photon and natural gadolinium doses. The most significant is the dose created by natural gadolinium. The amount of gadolinium at the irradiated region is changeable and depends on the gadolinium delivery agent and on the structure of the location where the agent is injected. To de- fine the time dependence of the gadolinium concentration ρ(t) in the irradiated region the pharmacokinetics of gadolinium delivery agent (Magnevist) was studied at intratumoral injection in mice and intramuscular injection in rats. A polynomial approximation was applied to the experimental data and the influence of ρ(t) on the relative change of the absorbed dose of gadolinium was studied.

  18. Absorbed dose thresholds and absorbed dose rate limitations for studies of electron radiation effects on polyetherimides

    NASA Technical Reports Server (NTRS)

    Long, Edward R., Jr.; Long, Sheila Ann T.; Gray, Stephanie L.; Collins, William D.

    1989-01-01

    The threshold values of total absorbed dose for causing changes in tensile properties of a polyetherimide film and the limitations of the absorbed dose rate for accelerated-exposure evaluation of the effects of electron radiation in geosynchronous orbit were studied. Total absorbed doses from 1 kGy to 100 MGy and absorbed dose rates from 0.01 MGy/hr to 100 MGy/hr were investigated, where 1 Gy equals 100 rads. Total doses less than 2.5 MGy did not significantly change the tensile properties of the film whereas doses higher than 2.5 MGy significantly reduced elongation-to-failure. There was no measurable effect of the dose rate on the tensile properties for accelerated electron exposures.

  19. An absorbed dose calorimeter for IMRT dosimetry

    NASA Astrophysics Data System (ADS)

    Duane, S.; Aldehaybes, M.; Bailey, M.; Lee, N. D.; Thomas, C. G.; Palmans, H.

    2012-10-01

    A new calorimeter for dosimetry in small and complex fields has been built. The device is intended for the direct determination of absorbed dose to water in moderately small fields and in composite fields such as IMRT treatments, and as a transfer instrument calibrated against existing absorbed dose standards in conventional reference conditions. The geometry, materials and mode of operation have been chosen to minimize detector perturbations when used in a water phantom, to give a reasonably isotropic response and to minimize the effects of heat transfer when the calorimeter is used in non-reference conditions in a water phantom. The size of the core is meant to meet the needs of measurement in IMRT treatments and is comparable to the size of the air cavity in a type NE2611 ionization chamber. The calorimeter may also be used for small field dosimetry. Initial measurements in reference conditions and in an IMRT head and neck plan, collapsed to gantry angle zero, have been made to estimate the thermal characteristics of the device, and to assess its performance in use. The standard deviation (estimated repeatability) of the reference absorbed dose measurements was 0.02 Gy (0.6%).

  20. The Fricke dosimeter as an absorbed dose to water primary standard for Ir-192 brachytherapy

    NASA Astrophysics Data System (ADS)

    El Gamal, Islam; Cojocaru, Claudiu; Mainegra-Hing, Ernesto; McEwen, Malcolm

    2015-06-01

    The aim of this project was to develop an absorbed dose to water primary standard for Ir-192 brachytherapy based on the Fricke dosimeter. To achieve this within the framework of the existing TG-43 protocol, a determination of the absorbed dose to water at the reference position, D(r0,θ0), was undertaken. Prior to this investigation, the radiation chemical yield of the ferric ions (G-value) at the Ir-192 equivalent photon energy (0.380 MeV) was established by interpolating between G-values obtained for Co-60 and 250 kV x-rays. An irradiation geometry was developed with a cylindrical holder to contain the Fricke solution and allow irradiations in a water phantom to be conducted using a standard Nucletron microSelectron V2 HDR Ir-192 afterloader. Once the geometry and holder were optimized, the dose obtained with the Fricke system was compared to the standard method used in North America, based on air-kerma strength. Initial investigations focused on reproducible positioning of the ring-shaped holder for the Fricke solution with respect to the Ir-192 source and obtaining an acceptable type A uncertainty in the optical density measurements required to yield the absorbed dose. Source positioning was found to be reproducible to better than 0.3 mm, and a careful cleaning and control procedure reduced the variation in optical density reading due to contamination of the Fricke solution by the PMMA holder. It was found that fewer than 10 irradiations were required to yield a type A standard uncertainty of less than 0.5%. Correction factors to take account of the non-water components of the geometry and the volume averaging effect of the Fricke solution volume were obtained from Monte Carlo calculations. A sensitivity analysis showed that the dependence on the input data used (e.g. interaction cross-sections) was small with a type B uncertainty for these corrections estimated to be 0.2%. The combined standard uncertainty in the determination of absorbed dose to water

  1. The Fricke dosimeter as an absorbed dose to water primary standard for Ir-192 brachytherapy.

    PubMed

    El Gamal, Islam; Cojocaru, Claudiu; Mainegra-Hing, Ernesto; McEwen, Malcolm

    2015-06-01

    The aim of this project was to develop an absorbed dose to water primary standard for Ir-192 brachytherapy based on the Fricke dosimeter. To achieve this within the framework of the existing TG-43 protocol, a determination of the absorbed dose to water at the reference position, D(r0,θ0), was undertaken. Prior to this investigation, the radiation chemical yield of the ferric ions (G-value) at the Ir-192 equivalent photon energy (0.380 MeV) was established by interpolating between G-values obtained for Co-60 and 250 kV x-rays.An irradiation geometry was developed with a cylindrical holder to contain the Fricke solution and allow irradiations in a water phantom to be conducted using a standard Nucletron microSelectron V2 HDR Ir-192 afterloader. Once the geometry and holder were optimized, the dose obtained with the Fricke system was compared to the standard method used in North America, based on air-kerma strength.Initial investigations focused on reproducible positioning of the ring-shaped holder for the Fricke solution with respect to the Ir-192 source and obtaining an acceptable type A uncertainty in the optical density measurements required to yield the absorbed dose. Source positioning was found to be reproducible to better than 0.3 mm, and a careful cleaning and control procedure reduced the variation in optical density reading due to contamination of the Fricke solution by the PMMA holder. It was found that fewer than 10 irradiations were required to yield a type A standard uncertainty of less than 0.5%.Correction factors to take account of the non-water components of the geometry and the volume averaging effect of the Fricke solution volume were obtained from Monte Carlo calculations. A sensitivity analysis showed that the dependence on the input data used (e.g. interaction cross-sections) was small with a type B uncertainty for these corrections estimated to be 0.2%.The combined standard uncertainty in the determination of absorbed dose to water at

  2. Genetic effects induced by neutrons in Drosophila melanogaster I. Determination of absorbed dose.

    PubMed

    Delfin, A; Paredes, L C; Zambrano, F; Guzmán-Rincón, J; Ureña-Nuñez, F

    2001-12-01

    A method to obtain the absorbed dose in Drosophila melanogaster irradiated in the thermal column facility of the Triga Mark III Reactor has been developed. The method is based on the measurements of neutron activation of gold foils produced by neutron capture to obtain the neutron fluxes. These fluxes, combined with the calculations of kinetic energy released per unit mass, enables one to obtain the absorbed doses in Drosophila melanogaster. PMID:11761104

  3. Measuring absorbed dose for i-CAT CBCT examinations in child, adolescent and adult phantoms

    PubMed Central

    Choi, E

    2015-01-01

    Objectives: Design and construct child and adolescent head phantoms to measure the absorbed doses imparted during dental CBCT and compare with the absorbed dose measured in an adult phantom. Methods: A child phantom was developed to represent the smallest patients receiving CBCT, usually for craniofacial developmental concerns, and an adolescent phantom was developed to represent healthy orthodontic patients. Absorbed doses were measured using a thimble ionization chamber for the custom-built child and adolescent phantoms and compared with measurements using a commercially available adult phantom. Imaging was performed with an i-CAT Next Generation (Imaging Sciences International, Hatfield, PA) CBCT using two different fields of view covering the craniofacial complex (130 mm high) or maxilla/mandible (60 mm high). Results: Measured absorbed doses varied depending on the location of the ionization chamber within the phantoms. For CBCT images obtained using the same protocol for all phantoms, the highest absorbed dose was measured in all locations of the small child phantom. The lowest absorbed dose was measured in the adult phantom. Conclusions: Images were obtained with the same protocol for the adult, adolescent and child phantoms. A consistent trend was observed with the highest absorbed dose being measured in the smallest phantom (child), while the lowest absorbed dose was measured in the largest phantom (adult). This study demonstrates the importance of child-sizing the dose by using dedicated paediatric protocols optimized for the imaging task, which is critical as children are more sensitive to harmful effects of radiation and have a longer life-span post-irradiation for radiation-induced symptoms to develop than do adults. PMID:25785822

  4. Absorbed dose to water: Standards and traceability for radiation oncology

    SciTech Connect

    Almond, P.R.

    1995-12-31

    Although the need for appropriate quantities and units for ionizing radiation has existed since shortly after discovery of X-rays, the quantities and units in general use today were not completely formalized until about 15 years ago. The development of appropriate national and international standards have also been ongoing. For many years the quantity, exposure, measured in units of roentgen was the national standard and they were also the quantity and units in which radiotherapy was described. With the introduction of megavoltage X-ray and electron-beam equipment and the adoption of the quantity {open_quotes}absorbed-dose{close_quotes} measured in units of rad (or gray) different approaches to calibrating these beams were needed. This was especially the case since the national standard in terms of exposure at a maximum photon energy for {sup 60}Co gamma rays was only available. Since the late 1960s various machine calibration protocols have been published. These protocols have to accommodate changes in modality, energy, quantities and units between the national standard and the user. Because of this, a new definition of traceability is proposed to accommodate the present system. By recording all intercomparisons and parameters used, an auditable calibration chain can be maintained. Even with the introduction of calibration protocols based upon national absorbed dose standards, the proposed traceability definition will still be needed.

  5. Reduction of absorbed doses in radiography of the facial skeleton

    SciTech Connect

    Julin, P.; Kraepelien, T.

    1984-11-01

    Radiation absorbed doses from radiography of the paranasal sinuses and the facial skeleton were measured with thermoluminescent dosimeters (TLD) on a phantom head using high-sensitivity screens in an Orbix stand. The entrance doses to the skin of the head ranged from 0.31 to 2.9 mGy per exposure. The absorbed dose from a full series of sinus exposures averaged 0.33 mGy for the oral mucous membrane, 0.33 mGy for the maxillary sinus mucous membrane, 0.11 mGy for the parotid gland, 0.15 mGy for the submandibular gland, 0.61 mGy for the eye lens, and 0.75 mGy for the thyroid gland region. A leaded soft collar adapted to the thyroid region reduced the thyroid doses by more than one order of magnitude, but also reduced the image field. The mean energy imparted from a full series of paranasal sinus projections was 4.8 mJ and from a total series of the facial skeleton, 7.9 mJ.

  6. Angular distributions of absorbed dose of Bremsstrahlung and secondary electrons induced by 18-, 28- and 38-MeV electron beams in thick targets.

    PubMed

    Takada, Masashi; Kosako, Kazuaki; Oishi, Koji; Nakamura, Takashi; Sato, Kouichi; Kamiyama, Takashi; Kiyanagi, Yoshiaki

    2013-03-01

    Angular distributions of absorbed dose of Bremsstrahlung photons and secondary electrons at a wide range of emission angles from 0 to 135°, were experimentally obtained using an ion chamber with a 0.6 cm(3) air volume covered with or without a build-up cap. The Bremsstrahlung photons and electrons were produced by 18-, 28- and 38-MeV electron beams bombarding tungsten, copper, aluminium and carbon targets. The absorbed doses were also calculated from simulated photon and electron energy spectra by multiplying simulated response functions of the ion chambers, simulated with the MCNPX code. Calculated-to-experimental (C/E) dose ratios obtained are from 0.70 to 1.57 for high-Z targets of W and Cu, from 15 to 135° and the C/E range from 0.6 to 1.4 at 0°; however, the values of C/E for low-Z targets of Al and C are from 0.5 to 1.8 from 0 to 135°. Angular distributions at the forward angles decrease with increasing angles; on the other hand, the angular distributions at the backward angles depend on the target species. The dependences of absorbed doses on electron energy and target thickness were compared between the measured and simulated results. The attenuation profiles of absorbed doses of Bremsstrahlung beams at 0, 30 and 135° were also measured.

  7. Computational Modeling of Cellular Effects Post-Irradiation with Low- and High-Let Particles and Different Absorbed Doses

    PubMed Central

    Tavares, Adriana Alexandre S.; Tavares, João Manuel R. S.

    2013-01-01

    The use of computational methods to improve the understanding of biological responses to various types of radiation is an approach where multiple parameters can be modelled and a variety of data is generated. This study compares cellular effects modelled for low absorbed doses against high absorbed doses. The authors hypothesized that low and high absorbed doses would contribute to cell killing via different mechanisms, potentially impacting on targeted tumour radiotherapy outcomes. Cellular kinetics following irradiation with selective low- and high-linear energy transfer (LET) particles were investigated using the Virtual Cell (VC) radiobiology algorithm. Two different cell types were assessed using the VC radiobiology algorithm: human fibroblasts and human crypt cells. The results showed that at lower doses (0.01 to 0.2 Gy), all radiation sources used were equally able to induce cell death (p>0.05, ANOVA). On the other hand, at higher doses (1.0 to 8.0 Gy), the radiation response was LET and dose dependent (p<0.05, ANOVA). The data obtained suggests that the computational methods used might provide some insight into the cellular effects following irradiation. The results also suggest that it may be necessary to re-evaluate cellular radiation-induced effects, particularly at low doses that could affect therapeutic effectiveness. PMID:23930101

  8. Space radiation absorbed dose distribution in a human phantom.

    PubMed

    Badhwar, G D; Atwell, W; Badavi, F F; Yang, T C; Cleghorn, T F

    2002-01-01

    The radiation risk to astronauts has always been based on measurements using passive thermoluminescent dosimeters (TLDs). The skin dose is converted to dose equivalent using an average radiation quality factor based on model calculations. The radiological risk estimates, however, are based on organ and tissue doses. This paper describes results from the first space flight (STS-91, 51.65 degrees inclination and approximately 380 km altitude) of a fully instrumented Alderson Rando phantom torso (with head) to relate the skin dose to organ doses. Spatial distributions of absorbed dose in 34 1-inch-thick sections measured using TLDs are described. There is about a 30% change in dose as one moves from the front to the back of the phantom body. Small active dosimeters were developed specifically to provide time-resolved measurements of absorbed dose rates and quality factors at five organ locations (brain, thyroid, heart/lung, stomach and colon) inside the phantom. Using these dosimeters, it was possible to separate the trapped-proton and the galactic cosmic radiation components of the doses. A tissue-equivalent proportional counter (TEPC) and a charged-particle directional spectrometer (CPDS) were flown next to the phantom torso to provide data on the incident internal radiation environment. Accurate models of the shielding distributions at the site of the TEPC, the CPDS and a scalable Computerized Anatomical Male (CAM) model of the phantom torso were developed. These measurements provided a comprehensive data set to map the dose distribution inside a human phantom, and to assess the accuracy and validity of radiation transport models throughout the human body. The results show that for the conditions in the International Space Station (ISS) orbit during periods near the solar minimum, the ratio of the blood-forming organ dose rate to the skin absorbed dose rate is about 80%, and the ratio of the dose equivalents is almost one. The results show that the GCR model dose

  9. Space radiation absorbed dose distribution in a human phantom

    NASA Technical Reports Server (NTRS)

    Badhwar, G. D.; Atwell, W.; Badavi, F. F.; Yang, T. C.; Cleghorn, T. F.

    2002-01-01

    The radiation risk to astronauts has always been based on measurements using passive thermoluminescent dosimeters (TLDs). The skin dose is converted to dose equivalent using an average radiation quality factor based on model calculations. The radiological risk estimates, however, are based on organ and tissue doses. This paper describes results from the first space flight (STS-91, 51.65 degrees inclination and approximately 380 km altitude) of a fully instrumented Alderson Rando phantom torso (with head) to relate the skin dose to organ doses. Spatial distributions of absorbed dose in 34 1-inch-thick sections measured using TLDs are described. There is about a 30% change in dose as one moves from the front to the back of the phantom body. Small active dosimeters were developed specifically to provide time-resolved measurements of absorbed dose rates and quality factors at five organ locations (brain, thyroid, heart/lung, stomach and colon) inside the phantom. Using these dosimeters, it was possible to separate the trapped-proton and the galactic cosmic radiation components of the doses. A tissue-equivalent proportional counter (TEPC) and a charged-particle directional spectrometer (CPDS) were flown next to the phantom torso to provide data on the incident internal radiation environment. Accurate models of the shielding distributions at the site of the TEPC, the CPDS and a scalable Computerized Anatomical Male (CAM) model of the phantom torso were developed. These measurements provided a comprehensive data set to map the dose distribution inside a human phantom, and to assess the accuracy and validity of radiation transport models throughout the human body. The results show that for the conditions in the International Space Station (ISS) orbit during periods near the solar minimum, the ratio of the blood-forming organ dose rate to the skin absorbed dose rate is about 80%, and the ratio of the dose equivalents is almost one. The results show that the GCR model dose

  10. Space radiation absorbed dose distribution in a human phantom.

    PubMed

    Badhwar, G D; Atwell, W; Badavi, F F; Yang, T C; Cleghorn, T F

    2002-01-01

    The radiation risk to astronauts has always been based on measurements using passive thermoluminescent dosimeters (TLDs). The skin dose is converted to dose equivalent using an average radiation quality factor based on model calculations. The radiological risk estimates, however, are based on organ and tissue doses. This paper describes results from the first space flight (STS-91, 51.65 degrees inclination and approximately 380 km altitude) of a fully instrumented Alderson Rando phantom torso (with head) to relate the skin dose to organ doses. Spatial distributions of absorbed dose in 34 1-inch-thick sections measured using TLDs are described. There is about a 30% change in dose as one moves from the front to the back of the phantom body. Small active dosimeters were developed specifically to provide time-resolved measurements of absorbed dose rates and quality factors at five organ locations (brain, thyroid, heart/lung, stomach and colon) inside the phantom. Using these dosimeters, it was possible to separate the trapped-proton and the galactic cosmic radiation components of the doses. A tissue-equivalent proportional counter (TEPC) and a charged-particle directional spectrometer (CPDS) were flown next to the phantom torso to provide data on the incident internal radiation environment. Accurate models of the shielding distributions at the site of the TEPC, the CPDS and a scalable Computerized Anatomical Male (CAM) model of the phantom torso were developed. These measurements provided a comprehensive data set to map the dose distribution inside a human phantom, and to assess the accuracy and validity of radiation transport models throughout the human body. The results show that for the conditions in the International Space Station (ISS) orbit during periods near the solar minimum, the ratio of the blood-forming organ dose rate to the skin absorbed dose rate is about 80%, and the ratio of the dose equivalents is almost one. The results show that the GCR model dose

  11. Graphite calorimetry for absorbed dose measurements in heavy-ion beams

    NASA Astrophysics Data System (ADS)

    Sakama, M.; Kanai, T.; Fukumura, A.

    In order to sophisticate the radiotherapy high accuracy knowledge of the absorbed dose delivered to the patient is essential The main methods of absolute dosimetry are indicated as follows a Dosimetry by ion chamber b Fricke dosimetry and c Calorimetry The calorimetry is most direct method of dosimetry due to direct measurement of energy deposit in principle and no requirement of information of radiation fields for the calibration Many countries tend to adopt the calorimetry to determine the standard absorbed dose to water and become to be capable of deciding the absorbed dose in precision of about 0 6 for photon and electron beams Despite the recent progress of particle therapy the parameters such as w-value and stopping power ratio for ionization chambers in the particles is not obtained accurately Therefore that causes uncertainty in determination of the absolute dose For this reason we developed a graphite calorimeter to obtain high precision absorbed dose and reduce the uncertainty for various beams When the absorbed dose of 1 Gy is irradiated to the sensitive volume the temperature rise is about 1 4 milliKelvins The performance require the resolution of plus or minus 7 micro Kelvins to measure it in precision of plus or minus 0 5 The stability within several micro Kelvins per minute is necessary to obtain measurable background The miniature glass bead thermistors were embedded in the sensitive volume to perform active control of temperature The resistance change of these thermistors is approximately 0 68 Ohms and 488 micro Ohms at

  12. Absorbed dose rates in tissue from prompt gamma emissions from near-thermal neutron absorption

    DOE PAGES

    Schwahn, Scott O.

    2015-10-01

    Prompt gamma emission data from the International Atomic Energy Agency s Prompt Gamma-ray Neutron Activation Analysis database are analyzed to determine the absorbed dose rates in tissue to be expected when natural elements are exposed in a near-thermal neutron environment.

  13. In vivo absorbed dose measurements in mammography using a new real-time luminescence technique.

    PubMed

    Aznar, M C; Hemdal, B; Medin, J; Marckmann, C J; Andersen, C E; Bøtter-Jensen, L; Andersson, I; Mattsson, S

    2005-04-01

    A dosimetry system based on radioluminescence (RL) and optically stimulated luminescence (OSL) from carbon doped aluminium oxide (Al2O3:C) crystals was developed for in vivo absorbed dose measurements in mammography. A small cylindrical crystal of Al2O3:C (diameter 0.48 mm and length 2 mm) was coupled to the end of a 1 mm diameter optical fibre cable. Owing to their small size and characteristic shape, these probes can be placed on the body surface in the field of view during the examination, without compromising the reading of the mammogram. Our new technique was tested with a mammography unit (Siemens Mammomat 3000) and screen-film technique over a range of clinically relevant X-ray energies. The results were compared with those obtained from an ionization chamber usually used for the determination of absorbed dose in mammography. The reproducibility of measurements was around 3% (1 standard deviation) at 4.5 mGy for both RL and OSL data. The dose response was found to be linear between 4.5 mGy and 30 mGy. The energy dependence of the system is around 18% between 23 kV and 35 kV. In vivo measurements were performed during three patient examinations. It was shown that entrance and exit doses could be measured. The presence of the small probes did not significantly interfere with the diagnostic quality of the images. Entrance doses estimated by RL/OSL results agreed within 3% with entrance surface dose values calculated from the ionization chamber measurements. These results indicate a considerable potential for use in routine control and in vivo dose measurements in mammography.

  14. Measurement of absorbed dose to water around an electronic brachytherapy source. Comparison of two dosimetry systems: lithium formate EPR dosimeters and radiochromic EBT2 film

    NASA Astrophysics Data System (ADS)

    Adolfsson, Emelie; White, Shane; Landry, Guillaume; Lund, Eva; Gustafsson, Håkan; Verhaegen, Frank; Reniers, Brigitte; Carlsson Tedgren, Åsa; Alm Carlsson, Gudrun

    2015-05-01

    Interest in high dose rate (HDR) electronic brachytherapy operating at 50 kV is increasing. For quality assurance it is important to identify dosimetry systems that can measure the absorbed doses in absolute terms which is difficult in this energy region. In this work a comparison is made between two dosimetry systems, EPR lithium formate dosimeters and radiochromic EBT2 film. Both types of dosimeters were irradiated simultaneously in a PMMA phantom using the Axxent EBS. Absorbed dose to water was determined at distances of 10 mm, 30 mm and 50 mm from the EBS. Results were traceable to different primary standards as regards to absorbed dose to water (EPR) and air kerma (EBT2). Monte Carlo simulations were used in absolute terms as a third estimate of absorbed dose to water. Agreement within the estimated expanded (k = 2) uncertainties (5% (EPR), 7% (EBT2)) was found between the results at 30 mm and 50 mm from the x-ray source. The same result was obtained in 4 repetitions of irradiation, indicating high precision in the measurements with both systems. At all distances, agreement between EPR and Monte Carlo simulations was shown as was also the case for the film measurements at 30mm and 50mm. At 10mm the geometry for the film measurements caused too large uncertainty in measured values depending on the exact position (within sub-mm distances) of the EBS and the 10 mm film results were exculded from comparison. This work has demonstrated good performance of the lithium formate EPR dosimetry system in accordance with earlier experiments at higher photon energies (192Ir HDR brachytherapy). It was also highlighted that there might be issues regarding the energy dependence and intrinsic efficiency of the EBT2 film that need to be considered for measurements using low energy sources.

  15. Plasma Membrane Permeabilization by 60- and 600-ns Electric Pulses Is Determined by the Absorbed Dose

    PubMed Central

    Ibey, Bennett L.; Xiao, Shu; Schoenbach, Karl H.; Murphy, Michael R.; Pakhomov, Andrei G.

    2008-01-01

    We explored how the effect of plasma membrane permeabilization by nanosecond-duration electric pulses (nsEP) depends on the physical characteristics of exposure. The resting membrane resistance (Rm) and membrane potential (MP) were measured in cultured GH3 and CHO cells by conventional whole-cell patch-clamp technique. Intact cells were exposed to a single nsEP (60 or 600 ns duration, 0-22 kV/cm), followed by patch-clamp measurements after a 2-3 min delay. Consistent with earlier findings, nsEP caused long-lasting Rm decrease, accompanied by the loss of MP. The threshold for these effects was about 6 kV/cm for 60 ns pulses, and about 1 kV/cm for 600 ns pulses. Further analysis established that it was neither pulse duration nor the E-field amplitude per se, but the absorbed dose that determined the magnitude of the biological effect. In other words, exposure to nsEP at either pulse duration caused equal effects if the absorbed doses were equal. The threshold absorbed dose to produce plasma membrane effects in either GH3 or CHO cells at either pulse duration was found to be at or below 10 mJ/g. Despite being determined by the dose, the nsEP effect clearly is not thermal, as the maximum heating at the threshold dose is less than 0.01 °C. The use of the absorbed dose as a universal exposure metric may help to compare and quantify nsEP sensitivity of different cell types and of cells in different physiological conditions. The absorbed dose may also prove to be a more useful metric than the incident E-field in determining safety limits for high peak, lowaverage power EMF emissions. PMID:18839412

  16. A Graphite Absorbed-Dose Calorimeter in the Quasi-Isothermal Mode of Operation

    NASA Astrophysics Data System (ADS)

    Witzani, J.; Duftschmid, K. E.; Strachotinsky, Ch; Leitner, A.

    1984-01-01

    A quasi-isothermal method of operating an absorbed-dose graphite calorimeter is described in theory and practice. In contrast with the well-known quasi-adiabatic operation, which entails temperature increases during measurements, in the quasi-isothermal mode the temperatures of the different graphite bodies remain constant except for small temperature drifts throughout the measurement. This implies that the temperature dependence of the specific heat of the absorber and of the sensitivity of the temperature sensor influence the absorbed-dose determination significantly less. The method is characterized by a power-compensating measuring principle which is illustrated with a 3-body graphite calorimeter. Comparisons of the quasi-isothermal with the quasi-adiabatic method of operation showed good agreement.

  17. On the suitability of ultrathin detectors for absorbed dose assessment in the presence of high-density heterogeneities

    SciTech Connect

    Bueno, M. Duch, M. A.; Carrasco, P.; Jornet, N.; Muñoz-Montplet, C.

    2014-08-15

    Purpose: The aim of this study was to evaluate the suitability of several detectors for the determination of absorbed dose in bone. Methods: Three types of ultrathin LiF-based thermoluminescent dosimeters (TLDs)—two LiF:Mg,Cu,P-based (MCP-Ns and TLD-2000F) and a{sup 7}Li-enriched LiF:Mg,Ti-based (MTS-7s)—as well as EBT2 Gafchromic films were used to measure percentage depth-dose distributions (PDDs) in a water-equivalent phantom with a bone-equivalent heterogeneity for 6 and 18 MV and a set of field sizes ranging from 5×5 cm{sup 2} to 20×20 cm{sup 2}. MCP-Ns, TLD-2000F, MTS-7s, and EBT2 have active layers of 50, 20, 50, and 30 μm, respectively. Monte Carlo (MC) dose calculations (PENELOPE code) were used as the reference and helped to understand the experimental results and to evaluate the potential perturbation of the fluence in bone caused by the presence of the detectors. The energy dependence and linearity of the TLDs’ response was evaluated. Results: TLDs exhibited flat energy responses (within 2.5%) and linearity with dose (within 1.1%) within the range of interest for the selected beams. The results revealed that all considered detectors perturb the electron fluence with respect to the energy inside the bone-equivalent material. MCP-Ns and MTS-7s underestimated the absorbed dose in bone by 4%–5%. EBT2 exhibited comparable accuracy to MTS-7s and MCP-Ns. TLD-2000F was able to determine the dose within 2% accuracy. No dependence on the beam energy or field size was observed. The MC calculations showed that a50 μm thick detector can provide reliable dose estimations in bone regardless of whether it is made of LiF, water or EBT’s active layer material. Conclusions: TLD-2000F was found to be suitable for providing reliable absorbed dose measurements in the presence of bone for high-energy x-ray beams.

  18. Absorbed dose assessment in newborns during x-ray examinations

    NASA Astrophysics Data System (ADS)

    Taipe, Patricia K.; Berrocal, Mariella J.; Carita, Raúl F.

    2012-02-01

    Often a newborn presents breathing problems during the early days of life, i.e. bronchopneumonia, wich are caused in most of cases, by aspirating a mixture of meconium and amniotic fluid. In these cases, it is necessary to make use of a radiograph, requested by the physician to reach a diagnosis. This paper seeks to evaluate the absorbed doses in neonates undergoing a radiograph. For this reason we try to simulate the real conditions in a X-ray room from Lima hospitals. With this finality we perform a simulation made according a questionnaire related to technical data of X-ray equipment, distance between the source and the neonate, and its position to be irradiated. The information obtained has been used to determine the absorbed dose by infants, using the MCNP code. Finally, the results are compared with reference values of international health agencies.

  19. Absorbed dose from traversing spherically symmetric, Gaussian radioactive clouds.

    PubMed

    Thompson, J M; Poston, J W

    1999-06-01

    If a large radioactive cloud is produced, sampling may require that an airplane traverse the cloud. A method to predict the absorbed dose to the aircrew from penetrating the radioactive cloud is needed. Dose rates throughout spherically symmetric Gaussian clouds of various sizes, and the absorbed doses from traversing the clouds, were calculated. Cloud size is a dominant parameter causing dose to vary by orders of magnitude for a given dose rate measured at some distance. A method to determine cloud size, based on dose rate readings at two or more distances from the cloud center, was developed. This method, however, failed to resolve the smallest cloud sizes from measurements made at 1,000 m to 2,000 m from the cloud center.

  20. Reduction of absorbed doses in radiography of the facial skeleton

    SciTech Connect

    Julin, P.; Kraepelien, T.

    1984-11-01

    Radiation absorbed doses from radiography of the paranasal sinuses and the facial skeleton were measured with thermoluminescent dosimeters (TLD) on a phantom head using high-sensitivity screens in an Orbix stand. The entrance doses to the skin of the head ranged from 0.31 to 2.9 mGy per exposure. The absorbed dose from a full series of sinus exposures averaged 0.33 mGy for the oral mucous membrane, 0.33 mGy for the maxillary sinus mucous membrane, 0.11 MgY for the parotid gland, 0.15 MgY for the submandibular gland, 0.61 mGy for the eye lens, and 0.75 mGy for the thyroid gland region. A leaded soft collar adapted to the thyroid region reduced the thyroid doses by more than one order of magnitude, but also reduced the image field.

  1. Graves' disease radioiodine-therapy: Choosing target absorbed doses for therapy planning

    SciTech Connect

    Willegaignon, J. Sapienza, M. T.; Coura-Filho, G. B.; Buchpiguel, C. A.; Watanabe, T.; Traino, A. C.

    2014-01-15

    {sup ~} was determined by the integration of measured {sup 131}I activity in the thyroid gland and based on T{sub eff}, respectively. No statistically significant relationship was found between therapeutic response and patients’ age, administered {sup 131}I activity (MBq), 24-h thyroid {sup 131}I uptake (%) or T{sub eff} (p ≥ 0.064); nonetheless, a good relationship was found between the therapeutic response and m{sub th} (p ≤ 0.035). Conclusions: According to the results of this study, the most effective thyroid absorbed dose to be targeted in GD therapy should not be based on a fixed dose but rather should be individualized based on the patient'sm{sub th} and A{sup ~}. To achieve a therapeutic success (i.e., durable euthyroidism or hypothyroidism) rate of at least 95%, a thyroid absorbed dose of 200 or 330 Gy is required depending on the methodology used for estimating m{sub th} and A{sup ~}.

  2. Mycosis Fungoides electron beam absorbed dose distribution using Fricke xylenol gel dosimetry

    NASA Astrophysics Data System (ADS)

    da Silveira, Michely C.; Sampaio, Francisco G. A.; Petchevist, Paulo C. D.; de Oliveira, André L.; Almeida, Adelaide de

    2011-12-01

    Radiotherapy uses ionizing radiation to destroy tumor cells. The absorbed dose control in the target volume is realized through radiation sensors, such as Fricke dosimeters and radiochromic film, which permit to realize bi-dimensional evaluations at once and because of that, they will be used in this study as well. Among the several types of cancer suitable for ionizing radiation treatment, the Mycosis Fungoides, a lymphoma that spreads on the skin surface and depth, requires for its treatment total body irradiation by high-energy electrons. In this work the Fricke xylenol gel (FXG) was used in order to obtain information about the absorbed dose distribution induced by the electron interactions with the irradiated tissues and to control this type of treatment. FXG can be considered as an alternative dosimeter, since up to now only films have been used. FXG sample cuvettes, simulating two selected tomos (cranium and abdomen) of the Rando anthropomorphic phantom, were positioned along with radiochromic films for comparison. The phantom was subjected to Stanford total body irradiation using 6 MeV electrons. Tomographic images were acquired for both dosimeters and evaluated through horizontal and vertical profiles along the tomographic centers. These profiles were obtained through a Matlab routine developed for this purpose. From the obtained results, one could infer that, for a superficial and internal patient irradiation, the FXG dosimeter showed an absorbed dose distribution similar to the one of the film. These results can validate the FXG dosimeter as an alternative dosimeter for the Mycosis Fungoides treatment planning.

  3. Microdosimetric measurements for neutron-absorbed dose determination during proton therapy

    PubMed Central

    Pérez-Andújar, Angélica; DeLuca, Paul M.; Thornton, Allan F.; Fitzek, Markus; Hecksel, Draik; Farr, Jonathan

    2012-01-01

    This work presents microdosimetric measurements performed at the Midwest Proton Radiotherapy Institute in Bloomington, Indiana, USA. The measurements were done simulating clinical setups with a water phantom and for a variety of stopping targets. The water phantom was irradiated by a proton spread out Bragg peak (SOBP) and by a proton pencil beam. Stopping target measurements were performed only for the pencil beam. The targets used were made of polyethylene, brass and lead. The objective of this work was to determine the neutron-absorbed dose for a passive and active proton therapy delivery, and for the interactions of the proton beam with materials typically in the beam line of a proton therapy treatment nozzle. Neutron doses were found to be higher at 45° and 90° from the beam direction for the SOBP configuration by a factor of 1.1 and 1.3, respectively, compared with the pencil beam. Meanwhile, the pencil beam configuration produced neutron-absorbed doses 2.2 times higher at 0° than the SOBP. For stopping targets, lead was found to dominate the neutron-absorbed dose for most angles due to a large production of low-energy neutrons emitted isotropically. PMID:22334761

  4. Developability assessment of clinical drug products with maximum absorbable doses.

    PubMed

    Ding, Xuan; Rose, John P; Van Gelder, Jan

    2012-05-10

    Maximum absorbable dose refers to the maximum amount of an orally administered drug that can be absorbed in the gastrointestinal tract. Maximum absorbable dose, or D(abs), has proved to be an important parameter for quantifying the absorption potential of drug candidates. The purpose of this work is to validate the use of D(abs) in a developability assessment context, and to establish appropriate protocol and interpretation criteria for this application. Three methods for calculating D(abs) were compared by assessing how well the methods predicted the absorption limit for a set of real clinical candidates. D(abs) was calculated for these clinical candidates by means of a simple equation and two computer simulation programs, GastroPlus and an program developed at Eli Lilly and Company. Results from single dose escalation studies in Phase I clinical trials were analyzed to identify the maximum absorbable doses for these compounds. Compared to the clinical results, the equation and both simulation programs provide conservative estimates of D(abs), but in general D(abs) from the computer simulations are more accurate, which may find obvious advantage for the simulations in developability assessment. Computer simulations also revealed the complex behavior associated with absorption saturation and suggested in most cases that the D(abs) limit is not likely to be achieved in a typical clinical dose range. On the basis of the validation findings, an approach is proposed for assessing absorption potential, and best practices are discussed for the use of D(abs) estimates to inform clinical formulation development strategies.

  5. Radiation environments and absorbed dose estimations on manned space missions

    NASA Astrophysics Data System (ADS)

    Curtis, S. B.; Atwell, W.; Beever, R.; Hardy, A.

    In order to make an assessment of radiation risk during manned missions in space, it is necessary first to have as accurate an estimation as possible of the radiation environment within the spacecraft to which the astronauts will be exposed. Then, with this knowledge and the inclusion of body self-shielding, estimations can be made of absorbed doses for various body organs (skin, eye, blood-forming organs, etc.). A review is presented of our present knowledge of the radiation environments and absorbed doses expected for several space mission scenarios selected for our development of the new radiation protection guidelines. The scenarios selected are a 90-day mission at an altitude (450 km) and orbital inclinations (28.5°, 57° and 90°) appropriate for NASA's Space Station, a 15-day sortie to geosynchronous orbit and a 90-day lunar mission. All scenarios chosen yielded dose equivalents between five and ten rem to the blood forming organs if no large solar particle event were encountered. Such particle events could add considerable exposure particularly to the skin and eye for all scenarios except the one at 28.5° orbital inclination.

  6. Strontium-89 therapy: measurement of absorbed dose to skeletal metastases.

    PubMed

    Blake, G M; Zivanovic, M A; Blaquiere, R M; Fine, D R; McEwan, A J; Ackery, D M

    1988-04-01

    We report measurements of absorbed dose to vertebral metastases in ten patients referred for 89Sr therapy for disseminated prostatic carcinoma. Patients received a tracer dose of 85Sr at the time of 89Sr treatment and metastatic strontium retention was monitored scintigraphically for 6 mo. Metastatic 85Sr activity corrected for tissue attenuation was measured using the conjugate view principle, with special care taken to eliminate errors due to the selection of the metastatic region of interest. Metastatic volume was determined from high resolution CT images, and density inferred from Hounsfield number using the QCT bone mineral calibration of Genant and Cann. The mean absorbed dose was 850 rad/mCi (23 cGy/MBq) with a range from 220-2260 rad/mCi (6 to 61 cGy/MBq). The wide range found was consistent with the variation expected to arise due to differences in strontium renal plasma clearance (range 0.1-11.81/day) and extent of skeletal metastatic disease (varying from two small metastases to a superscan on [99mTc]MDP images) among the patients studied. PMID:3351609

  7. Equilibration of a Graphite Absorbed-Dose Calorimeter and the Quasi-Isothermal Mode of Operation

    NASA Astrophysics Data System (ADS)

    Janssens, A.; Cottens, E.; Paulsen, A.; Poffijn, A.

    1986-01-01

    From a mathematical model of a three-body absorbed-dose calorimeter a procedure for achieving thermal equilibrium is developed which uses calculational methods to determine the exact amount and timing of electrical energy to be dissipated in the calorimetric bodies. This procedure is applied to the quasi-isothermal mode of operation in which a radiation beam and equivalent electrical heating are alternately used to keep the calorimetric bodies at temperatures as constant as possible. Measurements of the dose rate of a 60Co beam in graphite using this technique are reported.

  8. An international dosimetry exchange for boron neutron capture therapy. Part I: Absorbed dose measurements.

    PubMed

    Binns, P J; Riley, K J; Harling, O K; Kiger, W S; Munck af Rosenschöld, P M; Giusti, V; Capala, J; Sköld, K; Auterinen, I; Serén, T; Kotiluoto, P; Uusi-Simola, J; Marek, M; Viererbl, L; Spurny, F

    2005-12-01

    An international collaboration was organized to undertake a dosimetry exchange to enable the future combination of clinical data from different centers conducting neutron capture therapy trials. As a first step (Part I) the dosimetry group from the Americas, represented by MIT, visited the clinical centers at Studsvik (Sweden), VTT Espoo (Finland), and the Nuclear Research Institute (NRI) at Rez (Czech Republic). A combined VTT/NRI group reciprocated with a visit to MIT. Each participant performed a series of dosimetry measurements under equivalent irradiation conditions using methods appropriate to their clinical protocols. This entailed in-air measurements and dose versus depth measurements in a large water phantom. Thermal neutron flux as well as fast neutron and photon absorbed dose rates were measured. Satisfactory agreement in determining absorbed dose within the experimental uncertainties was obtained between the different groups although the measurement uncertainties are large, ranging between 3% and 30% depending upon the dose component and the depth of measurement. To improve the precision in the specification of absorbed dose amongst the participants, the individually measured dose components were normalized to the results from a single method. Assuming a boron concentration of 15 microg g(-1) that is typical of concentrations realized clinically with the boron delivery compound boronophenylalanine-fructose, systematic discrepancies in the specification of the total biologically weighted dose of up to 10% were apparent between the different groups. The results from these measurements will be used in future to normalize treatment plan calculations between the different clinical dosimetry protocols as Part II of this study.

  9. Absorbed Dose Determination Using Experimental and Analytical Predictions of X-Ray Spectra

    NASA Technical Reports Server (NTRS)

    Edwards, D. L.; Carruth, Ralph (Technical Monitor)

    2001-01-01

    Electron beam welding in a vacuum is a technology that NASA is investigating as a joining technique for manufacture of space structures. This investigation characterizes the x-ray environment due to operation of an in-vacuum electron beam welding tool and provides recommendations for adequate shielding for astronauts performing the in-vacuum electron beam welding. NASA, in a joint venture with the Russian Space Agency, was scheduled to perform a series of welding in space experiments on board the U.S. Space Shuttle. This series of experiments was named the international space welding experiment (ISWE). The hardware associated with the ISWE was leased to NASA by the Paton Welding Institute (PWI) in Ukraine for ground-based welding experiments in preparation for flight. Two ground tests were scheduled, using the ISWE electron beam welding tool, to characterize the radiation exposure to an astronaut during the operation of the ISWE. These radiation exposure tests used thermoluminescence dosimeters (TLD's) shielded with material currently used by astronauts during extravehicular activities to measure the radiation dose. The TLD's were exposed to x-ray radiation generated by operation of the ISWE in-vacuum electron beam welding tool. This investigation was the first known application of TLD's to measure absorbed dose from x rays of energy less than 10 keV. The ISWE hardware was returned to Ukraine before the issue of adequate shielding for the astronauts was completely verified. Therefore, alternate experimental and analytical methods were developed to measure and predict the x-ray spectral and intensity distribution generated by ISWE electron beam impact with metal. These x-ray spectra were normalized to an equivalent ISWE exposure, then used to calculate the absorbed radiation dose to astronauts. These absorbed dose values were compared to TLD measurements obtained during actual operation of the ISWE in-vacuum electron beam welding tool. The calculated absorbed dose

  10. Analysis of the Body Distribution of Absorbed Dose in the Organs of Three Species of Fish from Sepetiba Bay

    SciTech Connect

    Pereira, Wagner de S; Kelecom, Alphonse; Santos Gouvea, Rita de Cassia dos; Azevedo Py Junior, Delcy de

    2008-08-07

    The body distribution of Polonium-210 in three fishes from the Sepetiba Bay (Macrodon ancylodon, Micropogonias furnieri and Mugil curema) has been studied under the approach of the Department of Energy of the United States of America (DOE) that set the limit of absorbed dose rate in biota equal to 3.5x10{sup 3} {mu}Gy/y, and that also established the relation between dose rate (D) and radionuclide concentration (c) on a fish muscle fresh weight basis, as follows: D = 5.05 ExNxC, assuming that the radionuclide distribution is homogenous among organs. Two hypotheses were tested here, using statistical tools: 1) is the body distribution of absorbed dose homogenous among organs? and 2) is the body distribution of absorbed dose identical among studied fishes? It was concluded, as expected, that the distribution among organs is heterogeneous; but, unexpectedly, that the three fishes display identical body distribution pattern, although they belong to different trophic levels. Hence, concerning absorbed dose calculation, the statement that data distribution is homogenous must be understood merely as an approximation, at least in the case of Polonium-210.

  11. Red bone marrow doses, integral absorbed doses, and somatically effective dose equivalent from four maxillary occlusal projections

    SciTech Connect

    Berge, T.I.; Wohni, T.

    1984-02-01

    Phantom measurements of red bone marrow (RBM) doses, integral absorbed doses, and somatically effective dose equivalent (SEDE) from four different maxillary occlusal projections are presented. For each projection, different combinations of focus-skin distances and tube potentials were compared with regard to the patient's radiation load. The axial incisal view produced the highest patient exposures, with a maximum red bone marrow dose of 122.5 microGy/exposure, integral absorbed dose of 8.6 mJ/exposure, and SEDE values of 39.6 microSv/exposure. The corresponding values from the frontal, lateral occlusal, and tuber views ranged between 4% and 44% of the axial incisal view values for the integral absorbed dose and SEDE values, and between 0.3% and 3% for the red bone marrow doses. Increasing the focus-skin distance from 17.5 cm to 27 cm is accompanied by a 24% to 30% reduction in integral absorbed dose. Increasing the tube potential from 50 kV to 65 kV likewise results in a 23% reduction in absorbed energy.

  12. Radiation absorbed dose estimates for [1-carbon-11]-glucose in adults: The effects of hyperinsulinemia

    SciTech Connect

    Powers, W.J. |

    1996-10-01

    As preparation for studies of blood-brain glucose transport in diabetes mellitus, radiation absorbed dose estimates from intravenous administration of [1-{sup 11}C]-glucose for 24 internal organs, lens, blood and total body were calculated for three physiologic conditions: euinsulinemic euglycemia, hyperinsulinemic euglycemia and hyperinsulinemic hyperglycemia. Cumulated activities in blood, insulin-independent and insulin-dependent compartments were calculated from blood time-activity curves in normal human volunteers and macaques. Apportionment of cumulated activity to individual organs in insulin-dependent and insulin-independent compartments was based on previously published data. Absorbed doses were calculated with the computer program MIRDOSE 3 for the 70-kg adult phantom. S for blood was calculated separately. The heart wall, lungs and spleen were the organs receiving the highest dose. The effect of hyperinsulinemia was demonstrated by the increase in adsorbed dose to the muscle, heart and blood with a decrease to other internal organs. This effect was more pronounced during hyperinsulinemic hyperglycemia. Hyperinsulinemia produced a decrease in effective dose due to the decrease in cumulated activity in organs with specified weighting factors greater than 0.05. The effective dose per study for [1-{sup 11}C]-glucose is comparable to that reported for 2-deoxy-[2-{sup 18}F]-glucose. 43 refs., 1 fig., 4 tabs.

  13. A Comparison of Model Calculation and Measurement of Absorbed Dose for Proton Irradiation. Chapter 5

    NASA Technical Reports Server (NTRS)

    Zapp, N.; Semones, E.; Saganti, P.; Cucinotta, F.

    2003-01-01

    With the increase in the amount of time spent EVA that is necessary to complete the construction and subsequent maintenance of ISS, it will become increasingly important for ground support personnel to accurately characterize the radiation exposures incurred by EVA crewmembers. Since exposure measurements cannot be taken within the organs of interest, it is necessary to estimate these exposures by calculation. To validate the methods and tools used to develop these estimates, it is necessary to model experiments performed in a controlled environment. This work is such an effort. A human phantom was outfitted with detector equipment and then placed in American EMU and Orlan-M EVA space suits. The suited phantom was irradiated at the LLUPTF with proton beams of known energies. Absorbed dose measurements were made by the spaceflight operational dosimetrist from JSC at multiple sites in the skin, eye, brain, stomach, and small intestine locations in the phantom. These exposures are then modeled using the BRYNTRN radiation transport code developed at the NASA Langley Research Center, and the CAM (computerized anatomical male) human geometry model of Billings and Yucker. Comparisons of absorbed dose calculations with measurements show excellent agreement. This suggests that there is reason to be confident in the ability of both the transport code and the human body model to estimate proton exposure in ground-based laboratory experiments.

  14. The estimation of absorbed dose rates for non-human biota : an extended inter-comparison.

    SciTech Connect

    Batlle, J. V. I.; Beaugelin-Seiller, K.; Beresford, N. A.; Copplestone, D.; Horyna, J.; Hosseini, A.; Johansen, M.; Kamboj, S.; Keum, D.-K.; Kurosawa, N.; Newsome, L.; Olyslaegers, G.; Vandenhove, H.; Ryufuku, S.; Lynch, S. V.; Wood, M. D.; Yu, C.

    2011-05-01

    An exercise to compare 10 approaches for the calculation of unweighted whole-body absorbed dose rates was conducted for 74 radionuclides and five of the ICRP's Reference Animals and Plants, or RAPs (duck, frog, flatfish egg, rat and elongated earthworm), selected for this exercise to cover a range of body sizes, dimensions and exposure scenarios. Results were analysed using a non-parametric method requiring no specific hypotheses about the statistical distribution of data. The obtained unweighted absorbed dose rates for internal exposure compare well between the different approaches, with 70% of the results falling within a range of variation of {+-}20%. The variation is greater for external exposure, although 90% of the estimates are within an order of magnitude of one another. There are some discernible patterns where specific models over- or under-predicted. These are explained based on the methodological differences including number of daughter products included in the calculation of dose rate for a parent nuclide; source-target geometry; databases for discrete energy and yield of radionuclides; rounding errors in integration algorithms; and intrinsic differences in calculation methods. For certain radionuclides, these factors combine to generate systematic variations between approaches. Overall, the technique chosen to interpret the data enabled methodological differences in dosimetry calculations to be quantified and compared, allowing the identification of common issues between different approaches and providing greater assurance on the fundamental dose conversion coefficient approaches used in available models for assessing radiological effects to biota.

  15. The estimation of absorbed dose rates for non-human biota: an extended intercomparison.

    PubMed

    Vives i Batlle, J; Beaugelin-Seiller, K; Beresford, N A; Copplestone, D; Horyna, J; Hosseini, A; Johansen, M; Kamboj, S; Keum, D-K; Kurosawa, N; Newsome, L; Olyslaegers, G; Vandenhove, H; Ryufuku, S; Vives Lynch, S; Wood, M D; Yu, C

    2011-05-01

    An exercise to compare 10 approaches for the calculation of unweighted whole-body absorbed dose rates was conducted for 74 radionuclides and five of the ICRP's Reference Animals and Plants, or RAPs (duck, frog, flatfish egg, rat and elongated earthworm), selected for this exercise to cover a range of body sizes, dimensions and exposure scenarios. Results were analysed using a non-parametric method requiring no specific hypotheses about the statistical distribution of data. The obtained unweighted absorbed dose rates for internal exposure compare well between the different approaches, with 70% of the results falling within a range of variation of ±20%. The variation is greater for external exposure, although 90% of the estimates are within an order of magnitude of one another. There are some discernible patterns where specific models over- or under-predicted. These are explained based on the methodological differences including number of daughter products included in the calculation of dose rate for a parent nuclide; source-target geometry; databases for discrete energy and yield of radionuclides; rounding errors in integration algorithms; and intrinsic differences in calculation methods. For certain radionuclides, these factors combine to generate systematic variations between approaches. Overall, the technique chosen to interpret the data enabled methodological differences in dosimetry calculations to be quantified and compared, allowing the identification of common issues between different approaches and providing greater assurance on the fundamental dose conversion coefficient approaches used in available models for assessing radiological effects to biota. PMID:21113609

  16. Absorbed Dose and Dose Equivalent Calculations for Modeling Effective Dose

    NASA Technical Reports Server (NTRS)

    Welton, Andrew; Lee, Kerry

    2010-01-01

    While in orbit, Astronauts are exposed to a much higher dose of ionizing radiation than when on the ground. It is important to model how shielding designs on spacecraft reduce radiation effective dose pre-flight, and determine whether or not a danger to humans is presented. However, in order to calculate effective dose, dose equivalent calculations are needed. Dose equivalent takes into account an absorbed dose of radiation and the biological effectiveness of ionizing radiation. This is important in preventing long-term, stochastic radiation effects in humans spending time in space. Monte carlo simulations run with the particle transport code FLUKA, give absorbed and equivalent dose data for relevant shielding. The shielding geometry used in the dose calculations is a layered slab design, consisting of aluminum, polyethylene, and water. Water is used to simulate the soft tissues that compose the human body. The results obtained will provide information on how the shielding performs with many thicknesses of each material in the slab. This allows them to be directly applicable to modern spacecraft shielding geometries.

  17. Proton and photon absorbed-dose conversion coefficients for embryo and foetus from top-down irradiation geometry.

    PubMed

    Chen, Jing

    2007-01-01

    Absorbed-dose conversion coefficients are calculated for the embryo of 8 weeks and the foetus of 3, 6 or 9 months when the mother's body is exposed to protons and photons from top-down (TOP) direction. It provides data sets in addition to other standard irradiation geometries published previously. The TOP-irradiation geometry is considered here, because high-energy particles are often peaked from the TOP direction onboard aircrafts. The results show that absorbed-doses from high-energy particles could be underestimated significantly if isotropic (ISO) irradiation geometry is assumed. For protons of 100 GeV, absorbed-doses from TOP irradiation are approximately 2.3-2.9 times higher than the doses from ISO irradiation for different foetal ages. For 10 GeV photons, foetal doses from TOP irradiation are approximately 6.8-12 times higher than the doses from ISO irradiation. The coefficients from TOP-irradiation geometry are given in wide energy ranges, from 100 MeV to 100 GeV for protons and from 50 keV to 10 GeV for photons. They can, therefore, be used in various applications whenever exposure from the TOP-irradiation direction is concerned.

  18. Uncertainties in Monte Carlo-based absorbed dose calculations for an experimental benchmark.

    PubMed

    Renner, F; Wulff, J; Kapsch, R-P; Zink, K

    2015-10-01

    There is a need to verify the accuracy of general purpose Monte Carlo codes like EGSnrc, which are commonly employed for investigations of dosimetric problems in radiation therapy. A number of experimental benchmarks have been published to compare calculated values of absorbed dose to experimentally determined values. However, there is a lack of absolute benchmarks, i.e. benchmarks without involved normalization which may cause some quantities to be cancelled. Therefore, at the Physikalisch-Technische Bundesanstalt a benchmark experiment was performed, which aimed at the absolute verification of radiation transport calculations for dosimetry in radiation therapy. A thimble-type ionization chamber in a solid phantom was irradiated by high-energy bremsstrahlung and the mean absorbed dose in the sensitive volume was measured per incident electron of the target. The characteristics of the accelerator and experimental setup were precisely determined and the results of a corresponding Monte Carlo simulation with EGSnrc are presented within this study. For a meaningful comparison, an analysis of the uncertainty of the Monte Carlo simulation is necessary. In this study uncertainties with regard to the simulation geometry, the radiation source, transport options of the Monte Carlo code and specific interaction cross sections are investigated, applying the general methodology of the Guide to the expression of uncertainty in measurement. Besides studying the general influence of changes in transport options of the EGSnrc code, uncertainties are analyzed by estimating the sensitivity coefficients of various input quantities in a first step. Secondly, standard uncertainties are assigned to each quantity which are known from the experiment, e.g. uncertainties for geometric dimensions. Data for more fundamental quantities such as photon cross sections and the I-value of electron stopping powers are taken from literature. The significant uncertainty contributions are identified as

  19. SU-E-I-85: Absorbed Dose Estimation for a Commercially Available MicroCT Scanner

    SciTech Connect

    Lau, A; Ahmad, S; Chen, Y; Ren, L; Liu, H; Yang, K

    2015-06-15

    Purpose: To quantify the simulated absorbed dose delivered for a typical scan from a commercially available microCT scanner in order to aid in the dose estimation. Methods: The simulations were conducted using the Geant4 Monte Carlo Toolkit (version 10) with the standard electromagnetic classes. The Quantum FX microCT scanner (PerkinElmer, Waltham, MA) was modeled incorporating the energy fluence and angular distributions of generated photons, spatial dimensions of nominal source-to-object and source-to-detector distances. The energy distribution was measured using a spectrometer (X-123CdTe, Amptek Inc., Bedford, USA) with a 300 angular spread from the source for the 90 kVp X-ray beams with no additional filtration. The nominal distances from the source to object consisted of three setups: 154.0 mm, 104.0 mm, and 51.96 mm. Our simulations recorded the dose absorbed in a cylindrical phantom of PMMA with a fixed length of 2 cm and varying radii (10, 20, 30 and 40 mm) using 100 million incident photons. The averaged absorbed dose in the object was then quantified for all setups. An exposure measurement of 417 mR was taken using a Radcal 9095 system utilizing 10×9–180 ion chamber with the given technique of 90 kVp, 63 μA, and 12 s. The exposure rate was also simulated with same setup to calculate the conversion factor of the beam current and the number of incident photons. Results: For a typical cone-beam scan with non-filtered 90kVp, the dose coefficients (the absorbed dose per mAs) were 2.614, 2.549 and 2.467 μGy/mAs under source to object distance of 104 mm for the object diameters of 10 mm, 20 mm and 30 mm, respectively. Conclusion: A look-up table was developed where an investigator can estimate the delivered dose using this particular microCT given the scanning protocol (kVp and mAs) as well as the size of the scanned object.

  20. Uncertainties in Monte Carlo-based absorbed dose calculations for an experimental benchmark.

    PubMed

    Renner, F; Wulff, J; Kapsch, R-P; Zink, K

    2015-10-01

    There is a need to verify the accuracy of general purpose Monte Carlo codes like EGSnrc, which are commonly employed for investigations of dosimetric problems in radiation therapy. A number of experimental benchmarks have been published to compare calculated values of absorbed dose to experimentally determined values. However, there is a lack of absolute benchmarks, i.e. benchmarks without involved normalization which may cause some quantities to be cancelled. Therefore, at the Physikalisch-Technische Bundesanstalt a benchmark experiment was performed, which aimed at the absolute verification of radiation transport calculations for dosimetry in radiation therapy. A thimble-type ionization chamber in a solid phantom was irradiated by high-energy bremsstrahlung and the mean absorbed dose in the sensitive volume was measured per incident electron of the target. The characteristics of the accelerator and experimental setup were precisely determined and the results of a corresponding Monte Carlo simulation with EGSnrc are presented within this study. For a meaningful comparison, an analysis of the uncertainty of the Monte Carlo simulation is necessary. In this study uncertainties with regard to the simulation geometry, the radiation source, transport options of the Monte Carlo code and specific interaction cross sections are investigated, applying the general methodology of the Guide to the expression of uncertainty in measurement. Besides studying the general influence of changes in transport options of the EGSnrc code, uncertainties are analyzed by estimating the sensitivity coefficients of various input quantities in a first step. Secondly, standard uncertainties are assigned to each quantity which are known from the experiment, e.g. uncertainties for geometric dimensions. Data for more fundamental quantities such as photon cross sections and the I-value of electron stopping powers are taken from literature. The significant uncertainty contributions are identified as

  1. Using LiF:Mg,Cu,P TLDs to estimate the absorbed dose to water in liquid water around an {sup 192}Ir brachytherapy source

    SciTech Connect

    Lucas, P. Avilés Aubineau-Lanièce, I.; Lourenço, V.; Vermesse, D.; Cutarella, D.

    2014-01-15

    Purpose: The absorbed dose to water is the fundamental reference quantity for brachytherapy treatment planning systems and thermoluminescence dosimeters (TLDs) have been recognized as the most validated detectors for measurement of such a dosimetric descriptor. The detector response in a wide energy spectrum as that of an{sup 192}Ir brachytherapy source as well as the specific measurement medium which surrounds the TLD need to be accounted for when estimating the absorbed dose. This paper develops a methodology based on highly sensitive LiF:Mg,Cu,P TLDs to directly estimate the absorbed dose to water in liquid water around a high dose rate {sup 192}Ir brachytherapy source. Methods: Different experimental designs in liquid water and air were constructed to study the response of LiF:Mg,Cu,P TLDs when irradiated in several standard photon beams of the LNE-LNHB (French national metrology laboratory for ionizing radiation). Measurement strategies and Monte Carlo techniques were developed to calibrate the LiF:Mg,Cu,P detectors in the energy interval characteristic of that found when TLDs are immersed in water around an{sup 192}Ir source. Finally, an experimental system was designed to irradiate TLDs at different angles between 1 and 11 cm away from an {sup 192}Ir source in liquid water. Monte Carlo simulations were performed to correct measured results to provide estimates of the absorbed dose to water in water around the {sup 192}Ir source. Results: The dose response dependence of LiF:Mg,Cu,P TLDs with the linear energy transfer of secondary electrons followed the same variations as those of published results. The calibration strategy which used TLDs in air exposed to a standard N-250 ISO x-ray beam and TLDs in water irradiated with a standard{sup 137}Cs beam provided an estimated mean uncertainty of 2.8% (k = 1) in the TLD calibration coefficient for irradiations by the {sup 192}Ir source in water. The 3D TLD measurements performed in liquid water were obtained with a

  2. Measured absorbed dose rates from semi-infinite hemispherical volumes of 133Xe.

    PubMed

    Munyon, W J; Barber, D E; Howley, J R

    1986-07-01

    Surface absorbed dose rates from different hemispheric volumes of 133Xe have been measured directly with an extrapolation chamber. The results indicate that a linear relationship exists between the radius of the cloud volume and the surface absorbed dose rate for radii between 0 and 23 cm. If cloud volumes with radii larger than 23 cm are taken to be infinite with respect to the range of the charged particles emitted, the absorbed dose rate calculated based on that assumption will be within the uncertainty of any measurement of absorbed dose rate that might be made. For hemispheric volumes having radii less than or equal to 23 cm, the surface absorbed dose rate in tissue-equivalent material, in mGy h-1, is approximated (+/- 20%) by the product of [1.30 mGy h-1 cm-1 kBq-1 cm3] X [cloud radius, cm] X [cloud activity concentration, kBq cm-3].

  3. Absorbed dose rate in air in metropolitan Tokyo before the Fukushima Daiichi Nuclear Power Plant accident.

    PubMed

    Inoue, K; Hosoda, M; Fukushi, M; Furukawa, M; Tokonami, S

    2015-11-01

    The monitoring of absorbed dose rate in air has been carried out continually at various locations in metropolitan Tokyo after the accident of the Fukushima Daiichi Nuclear Power Plant. While the data obtained before the accident are needed to more accurately assess the effects of radionuclide contamination from the accident, detailed data for metropolitan Tokyo obtained before the accident have not been reported. A car-borne survey of the absorbed dose rate in air in metropolitan Tokyo was carried out during August to September 2003. The average absorbed dose rate in air in metropolitan Tokyo was 49±6 nGy h(-1). The absorbed dose rate in air in western Tokyo was higher compared with that in central Tokyo. Here, if the absorbed dose rate indoors in Tokyo is equivalent to that outdoors, the annual effective dose would be calculated as 0.32 mSv y(-1).

  4. Absorbed dose rate in air in metropolitan Tokyo before the Fukushima Daiichi Nuclear Power Plant accident.

    PubMed

    Inoue, K; Hosoda, M; Fukushi, M; Furukawa, M; Tokonami, S

    2015-11-01

    The monitoring of absorbed dose rate in air has been carried out continually at various locations in metropolitan Tokyo after the accident of the Fukushima Daiichi Nuclear Power Plant. While the data obtained before the accident are needed to more accurately assess the effects of radionuclide contamination from the accident, detailed data for metropolitan Tokyo obtained before the accident have not been reported. A car-borne survey of the absorbed dose rate in air in metropolitan Tokyo was carried out during August to September 2003. The average absorbed dose rate in air in metropolitan Tokyo was 49±6 nGy h(-1). The absorbed dose rate in air in western Tokyo was higher compared with that in central Tokyo. Here, if the absorbed dose rate indoors in Tokyo is equivalent to that outdoors, the annual effective dose would be calculated as 0.32 mSv y(-1). PMID:25944962

  5. Uncertainty analysis for absorbed dose from a brain receptor imaging agent

    SciTech Connect

    Aydogan, B.; Miller, L.F.; Sparks, R.B.; Stubbs, J.B.

    1999-01-01

    Absorbed dose estimates are known to contain uncertainties. A recent literature search indicates that prior to this study no rigorous investigation of uncertainty associated with absorbed dose has been undertaken. A method of uncertainty analysis for absorbed dose calculations has been developed and implemented for the brain receptor imaging agent {sup 123}I-IPT. The two major sources of uncertainty considered were the uncertainty associated with the determination of residence time and that associated with the determination of the S values. There are many sources of uncertainty in the determination of the S values, but only the inter-patient organ mass variation was considered in this work. The absorbed dose uncertainties were determined for lung, liver, heart and brain. Ninety-five percent confidence intervals of the organ absorbed dose distributions for each patient and for a seven-patient population group were determined by the ``Latin Hypercube Sampling`` method. For an individual patient, the upper bound of the 95% confidence interval of the absorbed dose was found to be about 2.5 times larger than the estimated mean absorbed dose. For the seven-patient population the upper bound of the 95% confidence interval of the absorbed dose distribution was around 45% more than the estimated population mean. For example, the 95% confidence interval of the population liver dose distribution was found to be between 1.49E+0.7 Gy/MBq and 4.65E+07 Gy/MBq with a mean of 2.52E+07 Gy/MBq. This study concluded that patients in a population receiving {sup 123}I-IPT could receive absorbed doses as much as twice as large as the standard estimated absorbed dose due to these uncertainties.

  6. Calculation of absorbed doses to water pools in severe accident sequences

    SciTech Connect

    Weber, C.F.

    1991-12-01

    A methodology is presented for calculating the radiation dose to a water pool from the decay of uniformly distributed nuclides in that pool. Motivated by the need to accurately model radiolysis reactions of iodine, direct application is made to fission product sources dissolved or suspended in containment sumps or pools during a severe nuclear reactor accident. Two methods of calculating gamma absorption are discussed - one based on point-kernal integration and the other based on Monte Carlo techniques. Using least-squares minimization, the computed results are used to obtain a correlation that relates absorbed dose to source energy and surface-to-volume ratio of the pool. This correlation is applied to most relevant fission product nuclides and used to actually calculate transient sump dose rate in a pressurized-water reactor (PWR) severe accident sequence.

  7. Absorbed dose determination using experimental and analytical predictions of x-ray spectra

    NASA Astrophysics Data System (ADS)

    Edwards, David Lee

    1999-10-01

    Electron beam welding in a vacuum is a technology that NASA is investigating as a joining technique for manufacture of space structures. The interaction of energetic electrons with metal produces x-rays. This investigation characterizes the x-ray environment due to operation of an in-vacuum electron beam welding tool and provides recommendations for adequate radiation shielding for astronauts performing the in-vacuum electron beam welding. NASA, in a joint venture with the Russian Space Agency, was scheduled to perform a series of welding in space experiments on board the United States Space Shuttle. This series of experiments was named the International Space Welding Experiment (ISWE). The hardware associated with the ISWE was leased to NASA, by the Paton Welding Institute (PWI) in Ukraine, for ground based welding experiments in preparation for flight. Two ground tests were scheduled, using the ISWE electron beam welding tool, to characterize the radiation exposure to an astronaut during the operation of the ISWE. These radiation exposure tests used Thermoluminescence Dosimeters (TLD's) shielded with material currently used by astronauts during Extra Vehicular Activities (EVA) to measure the radiation dose. The TLD's were exposed to x- ray radiation generated by operation of the ISWE in- vacuum electron beam welding tool. This investigation was the first known application of TLD's to measure absorbed dose from x-rays of energy less than 10 keV. The ISWE hardware was returned to Ukraine before the issue of adequate shielding for the astronauts was completely verified. Therefore alternate experimental and analytical methods were developed to measure and predict the x-ray spectral and intensity distribution generated by ISWE electron beam impact with metal. These x-ray spectra were normalized to an equivalent ISWE exposure then used to calculate the absorbed radiation dose to astronauts. These absorbed dose values were compared to TLD measurements obtained during

  8. Experimental determination of the absorbed dose to water in a scanned proton beam using a water calorimeter and an ionization chamber

    NASA Astrophysics Data System (ADS)

    Gagnebin, Solange; Twerenbold, Damian; Pedroni, Eros; Meer, David; Zenklusen, Silvan; Bula, Christian

    2010-03-01

    The absorbed dose to water is the reference physical quantity for the energy absorbed in tissue when exposed to beams of ionizing radiation in radiotherapy. The SI unit of absorbed dose to water is the gray (Gy = 1 J/kg). Ionization chambers are used as the dosimeters of choice in the clinical environment because they show a high reproducibility and are easy to use. However, ionization chambers have to be calibrated in order to convert the measured electrical charge into absorbed dose to water. In addition, protocols require these conversion factors to be SI traceable to a primary standard of absorbed dose to water. We present experimental results where the ionization chamber used for the dosimetry for the scanned proton beam facility at PSI is compared with the direct determination of absorbed dose to water from the METAS primary standard water calorimeter. The agreement of 3.2% of the dose values measured by the two techniques are within their respective statistical uncertainties.

  9. Absorbed dose simulations in near-surface regions using high dose rate Iridium-192 sources applied for brachytherapy

    NASA Astrophysics Data System (ADS)

    Moura, E. S.; Zeituni, C. A.; Sakuraba, R. K.; Gonçalves, V. D.; Cruz, J. C.; Júnior, D. K.; Souza, C. D.; Rostelato, M. E. C. M.

    2014-02-01

    Brachytherapy treatment with Iridium-192 high dose rate (HDR) sources is widely used for various tumours and it could be developed in many anatomic regions. Iridium-192 sources are inserted inside or close to the region that will be treated. Usually, the treatment is performed in prostate, gynaecological, lung, breast and oral cavity regions for a better clinical dose coverage compared with other techniques, such as, high energy photons and Cobalt-60 machines. This work will evaluate absorbed dose distributions in near-surface regions around Ir-192 HDR sources. Near-surface dose measurements are a complex task, due to the contribution of beta particles in the near-surface regions. These dose distributions should be useful for non-tumour treatments, such as keloids, and other non-intracavitary technique. For the absorbed dose distribution simulations the Monte Carlo code PENELOPE with the general code penEasy was used. Ir-192 source geometry and a Polymethylmethacrylate (PMMA) tube, for beta particles shield were modelled to yield the percentage depth dose (PDD) on a cubic water phantom. Absorbed dose simulations were realized at the central axis to yield the Ir-192 dose fall-off along central axis. The results showed that more than 99.2% of the absorbed doses (relative to the surface) are deposited in 5 cm depth but with slower rate at higher distances. Near-surface treatments with Ir-192 HDR sources yields achievable measurements and with proper clinical technique and accessories should apply as an alternative for treatment of lesions where only beta sources were used.

  10. The PTB primary standard for the absorbed-dose to water for I-125 interstitial brachytherapy sources

    NASA Astrophysics Data System (ADS)

    Schneider, T.

    2012-10-01

    The German national metrology institute (PTB) developed a primary standard in terms of absorbed-dose to water Dw for low-energy interstitial brachytherapy sources, which is based on an extrapolation chamber in a phantom of water-equivalent material. The method to determine Dw from extrapolation chamber measurements has been newly developed and is already described in the literature. With the chamber the absorbed-dose at 30 cm distance from the source is measured and the quantity is converted into the desired quantity, the absorbed-dose to water measured at 1 cm distance perpendicular to the source axis. In this paper, a synthesis of the work done within the EMRP Project: ‘TP2.JRP6: Increasing Cancer Treatment Efficacy Using 3D Brachytherapy’ is given and the final results and the final uncertainty budget are presented. Furthermore, an experimentally determined dose-rate constant for this seed type (BEBIG Symmetra I25.S16) is given based on the measurement of four different instances.

  11. Direct absorbed dose to water determination based on water calorimetry in scanning proton beam delivery

    SciTech Connect

    Sarfehnia, A.; Clasie, B.; Chung, E.; Lu, H. M.; Flanz, J.; Cascio, E.; Engelsman, M.; Paganetti, H.; Seuntjens, J.

    2010-07-15

    Purpose: The aim of this manuscript is to describe the direct measurement of absolute absorbed dose to water in a scanned proton radiotherapy beam using a water calorimeter primary standard. Methods: The McGill water calorimeter, which has been validated in photon and electron beams as well as in HDR {sup 192}Ir brachytherapy, was used to measure the absorbed dose to water in double scattering and scanning proton irradiations. The measurements were made at the Massachusetts General Hospital proton radiotherapy facility. The correction factors in water calorimetry were numerically calculated and various parameters affecting their magnitude and uncertainty were studied. The absorbed dose to water was compared to that obtained using an Exradin T1 Chamber based on the IAEA TRS-398 protocol. Results: The overall 1-sigma uncertainty on absorbed dose to water amounts to 0.4% and 0.6% in scattered and scanned proton water calorimetry, respectively. This compares to an overall uncertainty of 1.9% for currently accepted IAEA TRS-398 reference absorbed dose measurement protocol. The absorbed dose from water calorimetry agrees with the results from TRS-398 well to within 1-sigma uncertainty. Conclusions: This work demonstrates that a primary absorbed dose standard based on water calorimetry is feasible in scattered and scanned proton beams.

  12. Estimates of absorbed dose in different organs in children treated with radium for skin hemangiomas

    SciTech Connect

    Lundell, M.

    1994-12-01

    Between 1930 and 1959, more than 10,000 infants were treated at Radiumhemmet, Stockholm, with radium ({sup 226}Ra) needles and/or tubes for hemangioma of the skin. Absorbed dose to the brain, eye lenses, parotid glands, thyroid gland, breast enlarge, lungs, stomach, intestine, ovaries, testicles and bone marrow were calculated for each individual. The mean absorbed dose to the different organs ranged from 0.06 to 0.48 Gy. The highest absorbed dose was given to the breast (maximum 47.7 Gy). There was a wide dose range for each organ which was due mainly to differences in the distance between the applicator and the organ. The absorbed dose to all organs decreased on average by 32% during the study period. This was due to a 25% decrease in the treatment time and a change in the distribution of the treatment sites. 17 refs., 4 figs., 4 tabs.

  13. Monte Carlo Analysis of Pion Contribution to Absorbed Dose from Galactic Cosmic Rays

    NASA Technical Reports Server (NTRS)

    Aghara, S.K.; Battnig, S.R.; Norbury, J.W.; Singleterry, R.C.

    2009-01-01

    Accurate knowledge of the physics of interaction, particle production and transport is necessary to estimate the radiation damage to equipment used on spacecraft and the biological effects of space radiation. For long duration astronaut missions, both on the International Space Station and the planned manned missions to Moon and Mars, the shielding strategy must include a comprehensive knowledge of the secondary radiation environment. The distribution of absorbed dose and dose equivalent is a function of the type, energy and population of these secondary products. Galactic cosmic rays (GCR) comprised of protons and heavier nuclei have energies from a few MeV per nucleon to the ZeV region, with the spectra reaching flux maxima in the hundreds of MeV range. Therefore, the MeV - GeV region is most important for space radiation. Coincidentally, the pion production energy threshold is about 280 MeV. The question naturally arises as to how important these particles are with respect to space radiation problems. The space radiation transport code, HZETRN (High charge (Z) and Energy TRaNsport), currently used by NASA, performs neutron, proton and heavy ion transport explicitly, but it does not take into account the production and transport of mesons, photons and leptons. In this paper, we present results from the Monte Carlo code MCNPX (Monte Carlo N-Particle eXtended), showing the effect of leptons and mesons when they are produced and transported in a GCR environment.

  14. Monte Carlo analysis of pion contribution to absorbed dose from Galactic cosmic rays

    NASA Astrophysics Data System (ADS)

    Aghara, S. K.; Blattnig, S. R.; Norbury, J. W.; Singleterry, R. C.

    2009-04-01

    Accurate knowledge of the physics of interaction, particle production and transport is necessary to estimate the radiation damage to equipment used on spacecraft and the biological effects of space radiation. For long duration astronaut missions, both on the International Space Station and the planned manned missions to Moon and Mars, the shielding strategy must include a comprehensive knowledge of the secondary radiation environment. The distribution of absorbed dose and dose equivalent is a function of the type, energy and population of these secondary products. Galactic cosmic rays (GCR) comprised of protons and heavier nuclei have energies from a few MeV per nucleon to the ZeV region, with the spectra reaching flux maxima in the hundreds of MeV range. Therefore, the MeV-GeV region is most important for space radiation. Coincidentally, the pion production energy threshold is about 280 MeV. The question naturally arises as to how important these particles are with respect to space radiation problems. The space radiation transport code, HZETRN (High charge (Z) and Energy TRaNsport), currently used by NASA, performs neutron, proton and heavy ion transport explicitly, but it does not take into account the production and transport of mesons, photons and leptons. In this paper, we present results from the Monte Carlo code MCNPX (Monte Carlo N-Particle eXtended), showing the effect of leptons and mesons when they are produced and transported in a GCR environment.

  15. Evaluation of a deterministic grid-based Boltzmann solver (GBBS) for voxel-level absorbed dose calculations in nuclear medicine

    NASA Astrophysics Data System (ADS)

    Mikell, Justin; Cheenu Kappadath, S.; Wareing, Todd; Erwin, William D.; Titt, Uwe; Mourtada, Firas

    2016-06-01

    To evaluate the 3D Grid-based Boltzmann Solver (GBBS) code ATTILA ® for coupled electron and photon transport in the nuclear medicine energy regime for electron (beta, Auger and internal conversion electrons) and photon (gamma, x-ray) sources. Codes rewritten based on ATTILA are used clinically for both high-energy photon teletherapy and 192Ir sealed source brachytherapy; little information exists for using the GBBS to calculate voxel-level absorbed doses in nuclear medicine. We compared DOSXYZnrc Monte Carlo (MC) with published voxel-S-values to establish MC as truth. GBBS was investigated for mono-energetic 1.0, 0.1, and 0.01 MeV electron and photon sources as well as 131I and 90Y radionuclides. We investigated convergence of GBBS by analyzing different meshes ({{M}0},{{M}1},{{M}2} ), energy group structures ({{E}0},{{E}1},{{E}2} ) for each radionuclide component, angular quadrature orders (≤ft. {{S}4},{{S}8},{{S}16}\\right) , and scattering order expansions ({{P}0} –{{P}6} ); higher indices imply finer discretization. We compared GBBS to MC in (1) voxel-S-value geometry for soft tissue, lung, and bone, and (2) a source at the interface between combinations of lung, soft tissue, and bone. Excluding Auger and conversion electrons, MC agreed within  ≈5% of published source voxel absorbed doses. For the finest discretization, most GBBS absorbed doses in the source voxel changed by less than 1% compared to the next finest discretization along each phase space variable indicating sufficient convergence. For the finest discretization, agreement with MC in the source voxel ranged from  ‑3% to  ‑20% with larger differences at lower energies (‑3% for 1 MeV electron in lung to  ‑20% for 0.01 MeV photon in bone); similar agreement was found for the interface geometries. Differences between GBBS and MC in the source voxel for 90Y and 131I were  ‑6%. The GBBS ATTILA was benchmarked against MC in the nuclear medicine regime. GBBS can be a

  16. Evaluation of a deterministic grid-based Boltzmann solver (GBBS) for voxel-level absorbed dose calculations in nuclear medicine

    NASA Astrophysics Data System (ADS)

    Mikell, Justin; Cheenu Kappadath, S.; Wareing, Todd; Erwin, William D.; Titt, Uwe; Mourtada, Firas

    2016-06-01

    To evaluate the 3D Grid-based Boltzmann Solver (GBBS) code ATTILA ® for coupled electron and photon transport in the nuclear medicine energy regime for electron (beta, Auger and internal conversion electrons) and photon (gamma, x-ray) sources. Codes rewritten based on ATTILA are used clinically for both high-energy photon teletherapy and 192Ir sealed source brachytherapy; little information exists for using the GBBS to calculate voxel-level absorbed doses in nuclear medicine. We compared DOSXYZnrc Monte Carlo (MC) with published voxel-S-values to establish MC as truth. GBBS was investigated for mono-energetic 1.0, 0.1, and 0.01 MeV electron and photon sources as well as 131I and 90Y radionuclides. We investigated convergence of GBBS by analyzing different meshes ({{M}0},{{M}1},{{M}2} ), energy group structures ({{E}0},{{E}1},{{E}2} ) for each radionuclide component, angular quadrature orders (≤ft. {{S}4},{{S}8},{{S}16}\\right) , and scattering order expansions ({{P}0} -{{P}6} ); higher indices imply finer discretization. We compared GBBS to MC in (1) voxel-S-value geometry for soft tissue, lung, and bone, and (2) a source at the interface between combinations of lung, soft tissue, and bone. Excluding Auger and conversion electrons, MC agreed within  ≈5% of published source voxel absorbed doses. For the finest discretization, most GBBS absorbed doses in the source voxel changed by less than 1% compared to the next finest discretization along each phase space variable indicating sufficient convergence. For the finest discretization, agreement with MC in the source voxel ranged from  -3% to  -20% with larger differences at lower energies (-3% for 1 MeV electron in lung to  -20% for 0.01 MeV photon in bone); similar agreement was found for the interface geometries. Differences between GBBS and MC in the source voxel for 90Y and 131I were  -6%. The GBBS ATTILA was benchmarked against MC in the nuclear medicine regime. GBBS can be a viable

  17. Evaluation of a deterministic grid-based Boltzmann solver (GBBS) for voxel-level absorbed dose calculations in nuclear medicine.

    PubMed

    Mikell, Justin; Cheenu Kappadath, S; Wareing, Todd; Erwin, William D; Titt, Uwe; Mourtada, Firas

    2016-06-21

    To evaluate the 3D Grid-based Boltzmann Solver (GBBS) code ATTILA (®) for coupled electron and photon transport in the nuclear medicine energy regime for electron (beta, Auger and internal conversion electrons) and photon (gamma, x-ray) sources. Codes rewritten based on ATTILA are used clinically for both high-energy photon teletherapy and (192)Ir sealed source brachytherapy; little information exists for using the GBBS to calculate voxel-level absorbed doses in nuclear medicine. We compared DOSXYZnrc Monte Carlo (MC) with published voxel-S-values to establish MC as truth. GBBS was investigated for mono-energetic 1.0, 0.1, and 0.01 MeV electron and photon sources as well as (131)I and (90)Y radionuclides. We investigated convergence of GBBS by analyzing different meshes ([Formula: see text]), energy group structures ([Formula: see text]) for each radionuclide component, angular quadrature orders ([Formula: see text], and scattering order expansions ([Formula: see text]-[Formula: see text]); higher indices imply finer discretization. We compared GBBS to MC in (1) voxel-S-value geometry for soft tissue, lung, and bone, and (2) a source at the interface between combinations of lung, soft tissue, and bone. Excluding Auger and conversion electrons, MC agreed within  ≈5% of published source voxel absorbed doses. For the finest discretization, most GBBS absorbed doses in the source voxel changed by less than 1% compared to the next finest discretization along each phase space variable indicating sufficient convergence. For the finest discretization, agreement with MC in the source voxel ranged from  -3% to  -20% with larger differences at lower energies (-3% for 1 MeV electron in lung to  -20% for 0.01 MeV photon in bone); similar agreement was found for the interface geometries. Differences between GBBS and MC in the source voxel for (90)Y and (131)I were  -6%. The GBBS ATTILA was benchmarked against MC in the nuclear medicine regime. GBBS can be a

  18. Evaluation of a deterministic grid-based Boltzmann solver (GBBS) for voxel-level absorbed dose calculations in nuclear medicine.

    PubMed

    Mikell, Justin; Cheenu Kappadath, S; Wareing, Todd; Erwin, William D; Titt, Uwe; Mourtada, Firas

    2016-06-21

    To evaluate the 3D Grid-based Boltzmann Solver (GBBS) code ATTILA (®) for coupled electron and photon transport in the nuclear medicine energy regime for electron (beta, Auger and internal conversion electrons) and photon (gamma, x-ray) sources. Codes rewritten based on ATTILA are used clinically for both high-energy photon teletherapy and (192)Ir sealed source brachytherapy; little information exists for using the GBBS to calculate voxel-level absorbed doses in nuclear medicine. We compared DOSXYZnrc Monte Carlo (MC) with published voxel-S-values to establish MC as truth. GBBS was investigated for mono-energetic 1.0, 0.1, and 0.01 MeV electron and photon sources as well as (131)I and (90)Y radionuclides. We investigated convergence of GBBS by analyzing different meshes ([Formula: see text]), energy group structures ([Formula: see text]) for each radionuclide component, angular quadrature orders ([Formula: see text], and scattering order expansions ([Formula: see text]-[Formula: see text]); higher indices imply finer discretization. We compared GBBS to MC in (1) voxel-S-value geometry for soft tissue, lung, and bone, and (2) a source at the interface between combinations of lung, soft tissue, and bone. Excluding Auger and conversion electrons, MC agreed within  ≈5% of published source voxel absorbed doses. For the finest discretization, most GBBS absorbed doses in the source voxel changed by less than 1% compared to the next finest discretization along each phase space variable indicating sufficient convergence. For the finest discretization, agreement with MC in the source voxel ranged from  -3% to  -20% with larger differences at lower energies (-3% for 1 MeV electron in lung to  -20% for 0.01 MeV photon in bone); similar agreement was found for the interface geometries. Differences between GBBS and MC in the source voxel for (90)Y and (131)I were  -6%. The GBBS ATTILA was benchmarked against MC in the nuclear medicine regime. GBBS can be a

  19. A 3-Dimensional Absorbed Dose Calculation Method Based on Quantitative SPECT for Radionuclide Therapy: Evaluation for 131I Using Monte Carlo Simulation

    PubMed Central

    Ljungberg, Michael; Sjögreen, Katarina; Liu, Xiaowei; Frey, Eric; Dewaraja, Yuni; Strand, Sven-Erik

    2009-01-01

    A general method is presented for patient-specific 3-dimensional absorbed dose calculations based on quantitative SPECT activity measurements. Methods The computational scheme includes a method for registration of the CT image to the SPECT image and position-dependent compensation for attenuation, scatter, and collimator detector response performed as part of an iterative reconstruction method. A method for conversion of the measured activity distribution to a 3-dimensional absorbed dose distribution, based on the EGS4 (electron-gamma shower, version 4) Monte Carlo code, is also included. The accuracy of the activity quantification and the absorbed dose calculation is evaluated on the basis of realistic Monte Carlo–simulated SPECT data, using the SIMIND (simulation of imaging nuclear detectors) program and a voxel-based computer phantom. CT images are obtained from the computer phantom, and realistic patient movements are added relative to the SPECT image. The SPECT-based activity concentration and absorbed dose distributions are compared with the true ones. Results Correction could be made for object scatter, photon attenuation, and scatter penetration in the collimator. However, inaccuracies were imposed by the limited spatial resolution of the SPECT system, for which the collimator response correction did not fully compensate. Conclusion The presented method includes compensation for most parameters degrading the quantitative image information. The compensation methods are based on physical models and therefore are generally applicable to other radionuclides. The proposed evaluation methodology may be used as a basis for future intercomparison of different methods. PMID:12163637

  20. Estimation of radiation absorbed doses to the red marrow in radioimmunotherapy

    SciTech Connect

    Macey, D.J.; DeNardo, S.J.; DeNardo, G.L.; DeNardo, D.A.; Sui Shen

    1995-02-01

    Myelotoxicity is the dose-limiting factor in radioimmunotherapy. Traditional methods most commonly used to estimate the radiation adsorbed dose to the bone marrow of patients consider contribution from radionuclide in the blood and/or total body. Targeted therapies, such as radioimmunotherapy, add a third potential source for radiation to the bone marrow because the radiolabeled targeting molecules can accumulate specifically on malignant target cells infiltrating the bone marrow. A non-invasive method for estimating the radiation absorbed dose to the red marrow of patients who have received radiolabeled monoclonal antibodies (MoAb) has been developed and explored. The method depends on determining the cumulated activity in three contributing sources: (1) marrow; (2) blood; and (3) total body. The novel aspect of this method for estimating marrow radiation dose is derivation of the radiation dose for the entire red marrow from radiation dose estimates obtained by detection of cumulated activity in three lumbar vertebrae using a gamma camera. Contributions to the marrow radiation dose form marrow, blood, and total body cumulated activity were determined for patients who received an I-131 labeled MoAb, Lym-1, that reacts with malignant B-lymphocytes of chronic lymphocytic leukemia and nonHodgkin`s lymphoma. Six patients were selected for illustrative purposes because their vertebrae were readily visualized on lumbar images. 32 refs., 6 figs., 1 tab.

  1. Air kerma and absorbed dose standards for reference dosimetry in brachytherapy

    PubMed Central

    2014-01-01

    This article reviews recent developments in primary standards for the calibration of brachytherapy sources, with an emphasis on the currently most common photon-emitting radionuclides. The introduction discusses the need for reference dosimetry in brachytherapy in general. The following section focuses on the three main quantities, i.e. reference air kerma rate, air kerma strength and absorbed dose rate to water, which are currently used for the specification of brachytherapy photon sources and which can be realized with primary standards from first principles. An overview of different air kerma and absorbed dose standards, which have been independently developed by various national metrology institutes over the past two decades, is given in the next two sections. Other dosimetry techniques for brachytherapy will also be discussed. The review closes with an outlook on a possible transition from air kerma to absorbed dose to water-based calibrations for brachytherapy sources in the future. PMID:24814696

  2. Absorbed dose calculations to blood and blood vessels for internally deposited radionuclides

    SciTech Connect

    Akabani, G. ); Poston, J.W. . Dept. of Nuclear Engineering)

    1991-05-01

    At present, absorbed dose calculations for radionuclides in the human circulatory system used relatively simple models and are restricted in their applications. To determine absorbed doses to the blood and to the surface of the blood vessel wall, EGS4 Monte Carlo calculations were performed. Absorbed doses were calculated for the blood and the blood vessel wall (lumen) for different blood vessels sizes. The radionuclides chosen for this study were those commonly used in nuclear medicine. No diffusion of the radionuclide into the blood vessel was assumed nor cross fire between vessel was assumed. Results are useful in assessing the dose in blood and blood vessel walls for different nuclear medicine procedures. 6 refs., 6 figs., 5 tabs.

  3. Absorbed dose calculations to blood and blood vessels for internally deposited radionuclides

    SciTech Connect

    Akabani, G.; Poston, J.W. Sr. )

    1991-05-01

    At present, absorbed dose calculations for radionuclides in the human circulatory system used relatively simple models and are restricted in their applications. To determine absorbed doses to the blood and to the surface of the blood vessel wall, EGS4 Monte Carlo calculations were performed. Absorbed doses were calculated for the blood and the blood vessel wall (lumen) for different blood vessels sizes. The radionuclides chosen for this study were those commonly used in nuclear medicine. No penetration of the radionuclide into the blood vessel was assumed nor was cross fire between the vessel assumed. The results are useful in assessing the dose to blood and blood vessel walls for different nuclear medicine procedures.

  4. SU-E-T-516: Measurement of the Absorbed Dose Rate in Water Under Reference Conditions in a CyberKnife Unit

    SciTech Connect

    Aragon-Martinez, N; Hernandez-Guzman, A; Gomez-Munoz, A; Massillon-JL, G

    2014-06-01

    Purpose: This paper aims to measure the absorbed-dose-rate in a CyberKnife unit reference-field (6cm diameter) using three ionization chambers (IC) following the new IAEA/AAPM formalism and Gafchromic film (MD-V3-55 and EBT3) protocol according to our work reported previously. Methods: The absorbed-dose-rates were measured at 90cm and 70cm SSD in a 10cmx10cm field and at 70cm SSD in a 5.4cmx5.4cm equivalent to 6cm diameter field using a linac Varian iX. All measurements were performed at 10cm depth in water. The correction factors that account for the difference between the IC response on the reference field and the CyberKnife reference field, k-(Q-msr,Q)^(f-msr,f-ref), were evaluated and Gafchromic film were calibrated using the results obtained above. Under the CyberKnife reference conditions, the factors were used to measure the absorbed-dose-rate with IC according to the new formalism and the calibrated film was irradiated in water. The film calibration curve was used to evaluate the absorbed-dose-rate in the CyberKnife unit. Results: Difference up to 2.56% is observed between dose-rate measured with IC in the reference 10cmx10cm field, depending where the chamber was calibrated, which was not reflected in the correction factor k-(Q-msr,Q)^(f-msr,f-ref ) where variations of ~0.15%-0.5% were obtained. Within measurements uncertainties, maximum difference of 1.8% on the absorbed-dose-rate in the CyberKnife reference field is observed between all IC and the films Conclusion: Absorbed-dose-rate to water was measured in a CyberKnife reference field with acceptable accuracy (combined uncertainties ~1.32%-1.73%, k=1) using three IC and films. The MD-V3-55 film as well as the new IAEA/AAPM formalism can be considered as a suitable dosimetric method to measure absorbed-dose-rate to water in small and non-standard CyberKnife fields used in clinical treatments However, the EBT3 film is not appropriated due to the high uncertainty provided (combined uncertainty ~9%, k=1

  5. Estimating absorbed dose of pesticides in a field setting using biomonitoring data and pharmacokinetic models.

    PubMed

    Scher, Deanna P; Sawchuk, Ronald J; Alexander, Bruce H; Adgate, John L

    2008-01-01

    Linking biomarker data to pharmacokinetic (PK) models permits comparison of absorbed dose with a toxicological benchmark, which is an important step to understanding the health implications of pesticide exposure. The purpose of this analysis was to evaluate the feasibility of reconstructing the absorbed dose of two pesticides using PK models developed from biomarker data in a study of occupational application of these compounds. Twenty-four-hour urine samples were collected from farmers 24 h before through 96 h after a typical application of chlorpyrifos or 2,4-D. PK models were used to link the amounts found in urine samples to absorbed dose. Modeled total body dose estimates (in micrograms) were compared to measured dose from time 0-96 h. Despite the complexities surrounding the interpretation of biomonitoring data from a field setting, the models developed as part of this analysis accurately estimated the absorbed dose of 2,4-D and chlorpyrifos when collection of urine samples was largely complete. Over half of the farmers were excluded from modeling due to suspected noncompliance with urine collection or confounding exposure events, which highlights the importance of these issues for designing and interpreting biomonitoring data in future studies. Further evaluation of PK models in scenarios using single void samples is warranted for improving field-based dose assessments.

  6. New absorbed dose measurement with cylindrical water phantoms for multidetector CT

    NASA Astrophysics Data System (ADS)

    Ohno, Takeshi; Araki, Fujio; Onizuka, Ryota; Hioki, Kazunari; Tomiyama, Yuuki; Yamashita, Yusuke

    2015-06-01

    The aim of this study was to develop new dosimetry with cylindrical water phantoms for multidetector computed tomography (MDCT). The ionization measurement was performed with a Farmer ionization chamber at the center and four peripheral points in the body-type and head-type cylindrical water phantoms. The ionization was converted to the absorbed dose using a 60Co absorbed-dose-to-water calibration factor and Monte Carlo (MC) -calculated correction factors. The correction factors were calculated from MDCT (Brilliance iCT, 64-slice, Philips Electronics) modeled with GMctdospp (IMPS, Germany) software based on the EGSnrc MC code. The spectrum of incident x-ray beams and the configuration of a bowtie filter for MDCT were determined so that calculated photon intensity attenuation curves for aluminum (Al) and calculated off-center ratio (OCR) profiles in air coincided with those measured. The MC-calculated doses were calibrated by the absorbed dose measured at the center in both cylindrical water phantoms. Calculated doses were compared with measured doses at four peripheral points and the center in the phantom for various beam pitches and beam collimations. The calibration factors and the uncertainty of the absorbed dose determined using this method were also compared with those obtained by CTDIair (CT dose index in air). Calculated Al half-value layers and OCRs in air were within 0.3% and 3% agreement with the measured values, respectively. Calculated doses at four peripheral points and the centers for various beam pitches and beam collimations were within 5% and 2% agreement with measured values, respectively. The MC-calibration factors by our method were 44-50% lower than values by CTDIair due to the overbeaming effect. However, the calibration factors for CTDIair agreed within 5% with those of our method after correction for the overbeaming effect. Our method makes it possible to directly measure the absorbed dose for MDCT and is more robust and accurate than the

  7. New absorbed dose measurement with cylindrical water phantoms for multidetector CT.

    PubMed

    Ohno, Takeshi; Araki, Fujio; Onizuka, Ryota; Hioki, Kazunari; Tomiyama, Yuuki; Yamashita, Yusuke

    2015-06-01

    The aim of this study was to develop new dosimetry with cylindrical water phantoms for multidetector computed tomography (MDCT). The ionization measurement was performed with a Farmer ionization chamber at the center and four peripheral points in the body-type and head-type cylindrical water phantoms. The ionization was converted to the absorbed dose using a (60)Co absorbed-dose-to-water calibration factor and Monte Carlo (MC) -calculated correction factors. The correction factors were calculated from MDCT (Brilliance iCT, 64-slice, Philips Electronics) modeled with GMctdospp (IMPS, Germany) software based on the EGSnrc MC code. The spectrum of incident x-ray beams and the configuration of a bowtie filter for MDCT were determined so that calculated photon intensity attenuation curves for aluminum (Al) and calculated off-center ratio (OCR) profiles in air coincided with those measured. The MC-calculated doses were calibrated by the absorbed dose measured at the center in both cylindrical water phantoms. Calculated doses were compared with measured doses at four peripheral points and the center in the phantom for various beam pitches and beam collimations. The calibration factors and the uncertainty of the absorbed dose determined using this method were also compared with those obtained by CTDIair (CT dose index in air). Calculated Al half-value layers and OCRs in air were within 0.3% and 3% agreement with the measured values, respectively. Calculated doses at four peripheral points and the centers for various beam pitches and beam collimations were within 5% and 2% agreement with measured values, respectively. The MC-calibration factors by our method were 44-50% lower than values by CTDIair due to the overbeaming effect. However, the calibration factors for CTDIair agreed within 5% with those of our method after correction for the overbeaming effect. Our method makes it possible to directly measure the absorbed dose for MDCT and is more robust and accurate than the

  8. Assessment of out-of-field absorbed dose and equivalent dose in proton fields

    SciTech Connect

    Clasie, Ben; Wroe, Andrew; Kooy, Hanne; Depauw, Nicolas; Flanz, Jay; Paganetti, Harald; Rosenfeld, Anatoly

    2010-01-15

    . Conclusions: The dose deposited immediately downstream of the primary field, in these cases, is dominated by internally produced neutrons; therefore, scattered and scanned fields may have similar risk of second cancer in this region. The authors confirm that there is a reduction in the out-of-field dose in active scanning but the effect decreases with depth. GEANT4 is suitable for simulating the dose deposited outside the primary field. The agreement with measurements is comparable to or better than the agreement reported for other implementations of Monte Carlo models. Depending on the position, the absorbed dose outside the primary field is dominated by contributions from primary protons that may or may not have scattered in the brass collimating devices. This is noteworthy as the quality factor of the low LET protons is well known and the relative dose risk in this region can thus be assessed accurately.

  9. Uncertainties of organ-absorbed doses to patients from 18f-choline

    NASA Astrophysics Data System (ADS)

    Li, W. B.; Janzen, T.; Zankl, M.; Giussani, A.; Hoeschen, C.

    2011-03-01

    Radiation doses of radiopharmaceuticals to patients in nuclear medicine are, as the standard method, estimated by the administered activity, medical imaging (e.g. PET imaging), compartmental modeling and Monte Carlo simulation of radiation with reference digital human phantoms. However, in each of the contributing terms, individual uncertainty due to measurement techniques, patient variability and computation methods may propagate to the uncertainties of the calculated organ doses to the individual patient. To evaluate the overall uncertainties and the quality assurance of internal absorbed doses, a method was developed within the framework of the MADEIRA Project (Minimizing Activity and Dose with Enhanced Image quality by Radiopharmaceutical Administrations) to quantitatively analyze the uncertainties in each component of the organ absorbed doses after administration of 18F-choline to prostate cancer patients undergoing nuclear medicine diagnostics. First, on the basis of the organ PET and CT images of the patients as well as blood and urine samples, a model structure of 18F-choline was developed and the uncertainties of the model parameters were determined. Second, the model parameter values were sampled and biokinetic modeling using these sampled parameter values were performed. Third, the uncertainties of the new specific absorbed fraction (SAF) values derived with different phantoms representing individual patients were presented. Finally, the uncertainties of absorbed doses to the patients were calculated by applying the ICRP/ICRU adult male reference computational phantom. In addition to the uncertainty analysis, the sensitivity of the model parameters on the organ PET images and absorbed doses was indicated by coupling the model input and output using regression and partial correlation analysis. The results showed that the uncertainty factors of absorbed dose to patients are in most cases less than a factor of 2 without taking into account the uncertainties

  10. The energy dependence of lithium formate and alanine EPR dosimeters for medium energy x rays

    SciTech Connect

    Waldeland, Einar; Hole, Eli Olaug; Sagstuen, Einar; Malinen, Eirik

    2010-07-15

    Purpose: To perform a systematic investigation of the energy dependence of alanine and lilthium formate EPR dosimeters for medium energy x rays. Methods: Lithium formate and alanine EPR dosimeters were exposed to eight different x-ray beam qualities, with nominal potentials ranging from 50 to 200 kV. Following ionometry based on standards of absorbed dose to water, the dosimeters were given two different doses of approximately 3 and 6 Gy for each radiation quality, with three dosimeters for each dose. A reference series was also irradiated to three different dose levels at a {sup 60}Co unit. The dose to water energy response, that is, the dosimeter reading per absorbed dose to water relative to that for {sup 60}Co {gamma}-rays, was estimated for each beam quality. In addition, the energy response was calculated by Monte Carlo simulations and compared to the experimental energy response. Results: The experimental energy response estimates ranged from 0.89 to 0.94 and from 0.68 to 0.90 for lithium formate and alanine, respectively. The uncertainties in the experimental energy response estimates were typically 3%. The relative effectiveness, that is, the ratio of the experimental energy response to that following Monte Carlo simulations was, on average, 0.96 and 0.94 for lithium formate and alanine, respectively. Conclusions: This work shows that lithium formate dosimeters are less dependent on x-ray energy than alanine. Furthermore, as the relative effectiveness for both lithium formate and alanine were systematically less than unity, the yield of radiation-induced radicals is decreased following x-irradiation compared to irradiation with {sup 60}Co {gamma}-rays.

  11. Response functions for computing absorbed dose to skeletal tissues from neutron irradiation

    NASA Astrophysics Data System (ADS)

    Bahadori, Amir A.; Johnson, Perry; Jokisch, Derek W.; Eckerman, Keith F.; Bolch, Wesley E.

    2011-11-01

    Spongiosa in the adult human skeleton consists of three tissues—active marrow (AM), inactive marrow (IM) and trabecularized mineral bone (TB). AM is considered to be the target tissue for assessment of both long-term leukemia risk and acute marrow toxicity following radiation exposure. The total shallow marrow (TM50), defined as all tissues lying within the first 50 µm of the bone surfaces, is considered to be the radiation target tissue of relevance for radiogenic bone cancer induction. For irradiation by sources external to the body, kerma to homogeneous spongiosa has been used as a surrogate for absorbed dose to both of these tissues, as direct dose calculations are not possible using computational phantoms with homogenized spongiosa. Recent micro-CT imaging of a 40 year old male cadaver has allowed for the accurate modeling of the fine microscopic structure of spongiosa in many regions of the adult skeleton (Hough et al 2011 Phys. Med. Biol. 56 2309-46). This microstructure, along with associated masses and tissue compositions, was used to compute specific absorbed fraction (SAF) values for protons originating in axial and appendicular bone sites (Jokisch et al 2011 Phys. Med. Biol. 56 6857-72). These proton SAFs, bone masses, tissue compositions and proton production cross sections, were subsequently used to construct neutron dose-response functions (DRFs) for both AM and TM50 targets in each bone of the reference adult male. Kerma conditions were assumed for other resultant charged particles. For comparison, AM, TM50 and spongiosa kerma coefficients were also calculated. At low incident neutron energies, AM kerma coefficients for neutrons correlate well with values of the AM DRF, while total marrow (TM) kerma coefficients correlate well with values of the TM50 DRF. At high incident neutron energies, all kerma coefficients and DRFs tend to converge as charged-particle equilibrium is established across the bone site. In the range of 10 eV to 100 Me

  12. Absorbed Dose in the Uterus of a Three Months Pregnant Woman Due to 131I

    NASA Astrophysics Data System (ADS)

    Vega-Carrillo, Héctor René; Manzanares-Acuña, Eduardo; Hernández-Dávila, Víctor Martín; Arcos-Pichardo, Areli; Barquero, Raquel; Iñiguez, M. Pilar

    2006-09-01

    The use of 131I is widely used in diagnostic and treatment of patients. If the patient is pregnant the 131I presence in the thyroid it becomes a source of constant exposition to other organs and the fetus. In this study the absorbed dose in the uterus of a 3 months pregnant woman with 131I in her thyroid gland has been calculated. The dose was determined using Monte Carlo methods in which a detailed model of the woman has been developed. The dose was also calculated using a simple procedure that was refined including the photons' attenuation in the woman organs and body. To verify these results an experiment was carried out using a neck phantom with 131I. Comparing the results it was found that the simple calculation tend to overestimate the absorbed dose, by doing the corrections due to body and organs photon attenuation the dose is 0.14 times the Monte Carlo estimation.

  13. Absorbed Dose in the Uterus of a Three Months Pregnant Woman Due to 131I

    SciTech Connect

    Vega-Carrillo, Hector Rene; Manzanares-Acuna, Eduardo; Hernandez-Davila, Victor Martin; Arcos-Pichardo, Areli; Barquero, Raquel; Iniguez, M. Pilar

    2006-09-08

    The use of 131I is widely used in diagnostic and treatment of patients. If the patient is pregnant the 131I presence in the thyroid it becomes a source of constant exposition to other organs and the fetus. In this study the absorbed dose in the uterus of a 3 months pregnant woman with 131I in her thyroid gland has been calculated. The dose was determined using Monte Carlo methods in which a detailed model of the woman has been developed. The dose was also calculated using a simple procedure that was refined including the photons' attenuation in the woman organs and body. To verify these results an experiment was carried out using a neck phantom with 131I. Comparing the results it was found that the simple calculation tend to overestimate the absorbed dose, by doing the corrections due to body and organs photon attenuation the dose is 0.14 times the Monte Carlo estimation.

  14. Uneven surface absorbed dose distribution in electron-accelerator irradiation of rubber items

    SciTech Connect

    Gorbunov, I.F.; Pashinin, V.I.; Vanyushkin, B.M.

    1988-02-01

    Electron accelerators for industrial use are equipped with scanning devices, where the scan frequency or linear velocity along the window may vary. In a flow technology, where the items are transported to the irradiation zone at a set rate, the speed of an item may be comparable with the scan speed, so there is substantial nonuniformity in the absorbed dose, which adversely affects the quality. We have examined the dose nonuniformity for long rubber items during vulcanization by means of LUE-8-5RV and ELV-2 accelerators. The absorbed dose is calculated for an elementary part along which the irradiation is uniform on the assumption that current density distribution in the unswept beam is uniform as a result of scattering in the foil.

  15. Absorbed doses of lungs from radon retained in airway lumens of mice and rats.

    PubMed

    Sakoda, Akihiro; Ishimori, Yuu; Yamaoka, Kiyonori; Kataoka, Takahiro; Mitsunobu, Fumihiro

    2013-08-01

    This paper provides absorbed doses arising from radon gas in air retained in lung airway lumens. Because radon gas exposure experiments often use small animals, the calculation was performed for mice and rats. For reference, the corresponding computations were also done for humans. Assuming that radon concentration in airway lumens is the same as that in the environment, its progeny's production in and clearance from airways were simulated. Absorbed dose rates were obtained for three lung regions and the whole lung, considering that secretory and basal cells are sensitive to radiation. The results showed that absorbed dose rates for all lung regions and whole lung generally increase from mice to rats to humans. For example, the dose rates for the whole lung were 25.4 in mice, 41.7 in rats, and 59.9 pGy (Bq m⁻³)⁻¹ h⁻¹ in humans. Furthermore, these values were also compared with lung dose rates from two other types of exposures, that is, due to inhalation of radon or its progeny, which were already reported. It was confirmed that the direct inhalation of radon progeny in the natural environment, which is known as a cause of lung cancer, results in the highest dose rates for all species. Based on the present calculations, absorbed dose rates of the whole lung from radon gas were lower by a factor of about 550 (mice), 200 (rats), or 70 (humans) than those from radon progeny inhalation. The calculated dose rate values are comparatively small. Nevertheless, the present study is considered to contribute to our understanding of doses from inhalation of radon and its progeny.

  16. Electron paramagnetic resonance measurements of absorbed dose in teeth from citizens of Ozyorsk.

    PubMed

    Wieser, A; Vasilenko, E; Aladova, E; Fattibene, P; Semiochkina, N; Smetanin, M

    2014-05-01

    In 1945, within the frame of the Uranium Project for the production of nuclear weapons, the Mayak nuclear facilities were constructed at the Lake Irtyash in the Southern Urals, Russia. The nuclear workers of the Mayak Production Association (MPA), who lived in the city of Ozyorsk, are the focus of epidemiological studies for the assessment of health risks due to protracted exposure to ionising radiation. Electron paramagnetic resonance measurements of absorbed dose in tooth enamel have already been used in the past, in an effort to validate occupational external doses that were evaluated in the Mayak Worker Dosimetry System. In the present study, 229 teeth of Ozyorsk citizens not employed at MPA were investigated for the assessment of external background exposure in Ozyorsk. The annually absorbed dose in tooth enamel from natural background radiation was estimated to be (0.7 ± 0.3) mGy. For citizens living in Ozyorsk during the time of routine noble gas releases of the MPA, which peaked in 1953, the average excess absorbed dose in enamel above natural background was (36 ± 29) mGy, which is consistent with the gamma dose obtained by model calculations. In addition, there were indications of possible accidental gaseous MPA releases that affected the population of Ozyorsk, during the early and late MPA operation periods, before 1951 and after 1960. PMID:24604722

  17. Absorbed Dose Rate Due to Intake of Natural Radionuclides by Tilapia Fish (Tilapia nilotica,Linnaeus, 1758) Estimated Near Uranium Mining at Caetité, Bahia, Brazil

    NASA Astrophysics Data System (ADS)

    Pereira, Wagner de S.; Kelecom, Alphonse; Py Júnior, Delcy de Azevedo

    2008-08-01

    The uranium mining at Caetité (Uranium Concentrate Unit—URA) is in its operational phase. Aiming to estimate the radiological environmental impact of the URA, a monitoring program is underway. In order to preserve the biota of the deleterious effects from radiation and to act in a pro-active way as expected from a licensing body, the present work aims to use an environmental protection methodology based on the calculation of absorbed dose rate in biota. Thus, selected target organism was the Tilapia fish (Tilapia nilotica, Linnaeus, 1758) and the radionuclides were: uranium (U-238), thorium (Th-232), radium (Ra-226 and Ra-228) and lead (Pb-210). As, in Brazil there are no radiation exposure limits adopted for biota the value proposed by the Department of Energy (DOE) of the United States of 3.5×103 μGy y-1 has been used. The derived absorbed dose rate calculated for Tilapia was 2.51×100 μGy y-1, that is less than 0.1% of the dose limit established by DOE. The critical radionuclide was Ra-226, with 56% of the absorbed dose rate, followed by U-238 with 34% and Th-232 with 9%. This value of 0.1% of the limit allows to state that, in the operational conditions analyzed, natural radionuclides do not represent a radiological problem to biota.

  18. Absorbed Dose Rate Due to Intake of Natural Radionuclides by Tilapia Fish (Tilapia nilotica,Linnaeus, 1758) Estimated Near Uranium Mining at Caetite, Bahia, Brazil

    SciTech Connect

    Pereira, Wagner de S; Kelecom, Alphonse

    2008-08-07

    The uranium mining at Caetite (Uranium Concentrate Unit--URA) is in its operational phase. Aiming to estimate the radiological environmental impact of the URA, a monitoring program is underway. In order to preserve the biota of the deleterious effects from radiation and to act in a pro-active way as expected from a licensing body, the present work aims to use an environmental protection methodology based on the calculation of absorbed dose rate in biota. Thus, selected target organism was the Tilapia fish (Tilapia nilotica, Linnaeus, 1758) and the radionuclides were: uranium (U-238), thorium (Th-232), radium (Ra-226 and Ra-228) and lead (Pb-210). As, in Brazil there are no radiation exposure limits adopted for biota the value proposed by the Department of Energy (DOE) of the United States of 3.5x10{sup 3} {mu}Gy y{sup -1} has been used. The derived absorbed dose rate calculated for Tilapia was 2.51x10{sup 0} {mu}Gy y{sup -1}, that is less than 0.1% of the dose limit established by DOE. The critical radionuclide was Ra-226, with 56% of the absorbed dose rate, followed by U-238 with 34% and Th-232 with 9%. This value of 0.1% of the limit allows to state that, in the operational conditions analyzed, natural radionuclides do not represent a radiological problem to biota.

  19. Structural changes caused by radiation-induced reduction and radiolysis: the effect of X-ray absorbed dose in a fungal multicopper oxidase

    PubMed Central

    De la Mora, Eugenio; Lovett, Janet E.; Blanford, Christopher F.; Garman, Elspeth F.; Valderrama, Brenda; Rudino-Pinera, Enrique

    2012-01-01

    X-ray radiation induces two main effects at metal centres contained in protein crystals: radiation-induced reduction and radiolysis and a resulting decrease in metal occupancy. In blue multicopper oxidases (BMCOs), the geometry of the active centres and the metal-to-ligand distances change depending on the oxidation states of the Cu atoms, suggesting that these alterations are catalytically relevant to the binding, activation and reduction of O2. In this work, the X-ray-determined three-dimensional structure of laccase from the basidiomycete Coriolopsis gallica (Cg L), a high catalytic potential BMCO, is described. By combining spectroscopic techniques (UV–Vis, EPR and XAS) and X-ray crystallography, structural changes at and around the active copper centres were related to pH and absorbed X-­ray dose (energy deposited per unit mass). Depletion of two of the four active Cu atoms as well as low occupancies of the remaining Cu atoms, together with different conformations of the metal centres, were observed at both acidic pH and high absorbed dose, correlating with more reduced states of the active coppers. These observations provide additional evidence to support the role of flexibility of copper sites during O2 reduction. This study supports previous observations indicating that interpretations regarding redox state and metal coordination need to take radiation effects explicitly into account. PMID:22525754

  20. Measurement of absorbed dose-to-water for an HDR {sup 192}Ir source with ionization chambers in a sandwich setup

    SciTech Connect

    Araki, Fujio; Kouno, Tomohiro; Ohno, Takeshi; Kakei, Kiyotaka; Yoshiyama, Fumiaki; Kawamura, Shinji

    2013-09-15

    Purpose: In this study, a dedicated device for ion chamber measurements of absorbed dose-to-water for a Nucletron microSelectron-v2 HDR {sup 192}Ir brachytherapy source is presented. The device uses two ionization chambers in a so-called sandwich assembly. Using this setup and by taking the average reading of the two chambers, any dose error due to difficulties in absolute positioning (centering) of the source in between the chambers is cancelled to first order. The method's accuracy was examined by comparing measurements with absorbed dose-to-water determination based on the AAPM TG-43 protocol.Methods: The optimal source-to-chamber distance (SCD) for {sup 192}Ir dosimetry was determined from ion chamber measurements in a water phantom. The {sup 192}Ir source was sandwiched between two Exradin A1SL chambers (0.057 cm{sup 3}) at the optimal SCD separation. The measured ionization was converted to the absorbed dose-to-water using a {sup 60}Co calibration factor and a Monte Carlo-calculated beam quality conversion factor, k{sub Q}, for {sup 60}Co to {sup 192}Ir. An uncertainty estimate of the proposed method was determined based on reproducibility of measurements at different institutions for the same type of source.Results: The optimal distance for the A1SL chamber measurements was determined to be 5 cm from the {sup 192}Ir source center, considering the depth dependency of k{sub Q} for {sup 60}Co to {sup 192}Ir and the chamber positioning. The absorbed dose to water measured at (5 cm, 90°) on the transverse axis was 1.3% lower than TG-43 values and its reproducibility and overall uncertainty were 0.8% and 1.7%, respectively. The measurement doses at anisotropic points agreed within 1.5% with TG-43 values.Conclusions: The ion chamber measurement of absorbed dose-to-water with a sandwich method for the {sup 192}Ir source provides a more accurate, direct, and reference dose compared to the dose-to-water determination based on air-kerma strength in the TG-43 protocol

  1. Mercury exposure from dental amalgam fillings: absorbed dose and the potential for adverse health effects.

    PubMed

    Mackert, J R; Berglund, A

    1997-01-01

    This review examines the question of whether adverse health effects are attributable to amalgam-derived mercury. The issue of absorbed dose of mercury from amalgam is addressed first. The use of intra-oral Hg vapor measurements to estimate daily uptake must take into account the differences between the collection volume and flow rate of the measuring instrument and the inspiratory volume and flow rate of air through the mouth during inhalation of a single breath. Failure to account for these differences will result in substantial overestimation of the absorbed dose. Other factors that must be considered when making estimates of Hg uptake from amalgam include the accurate measurement of baseline (unstimulated) mercury release rates and the greater stimulation of Hg release afforded by chewing gum relative to ordinary food. The measured levels of amalgam-derived mercury in brain, blood, and urine are shown to be consistent with low absorbed doses (1-3 micrograms/day). Published relationships between the number of amalgam surfaces and urine levels are used to estimate the number of amalgam surfaces that would be required to produce the 30 micrograms/g creatinine urine mercury level stated by WHO to be associated with the most subtle, pre-clinical effects in the most sensitive individuals. From 450 to 530 amalgam surfaces would be required to produce the 30 micrograms/g creatinine urine mercury level for people without any excessive gum-chewing habits. The potential for adverse health effects and for improvement in health following amalgam removal is also addressed. Finally, the issue of whether any material can ever be completely exonerated of claims of producing adverse health effects is considered.

  2. Fetus absorbed dose evaluation in head and neck radiotherapy procedures of pregnant patients.

    PubMed

    da Costa, Etieli C; da Rosa, Luiz Antonio R; Batista, Delano Valdivino S

    2015-06-01

    In this work the head and neck cancer treatment of a pregnant patient was experimentally simulated. A female anthropomorphic Alderson phantom was used and the absorbed dose to the fetus was evaluated protecting the patient's abdomen with a 7cm lead layer and using no abdomen shielding. The target volume dose was 50Gy. The fetus doses evaluated with and without the lead shielding were, respectively, 0.52±0.039 and 0.88±0.052cGy. PMID:25620113

  3. Fine-Resolution Voxel S Values for Constructing Absorbed Dose Distributions at Variable Voxel Size

    PubMed Central

    Dieudonné, Arnaud; Hobbs, Robert F.; Bolch, Wesley E.; Sgouros, George; Gardin, Isabelle

    2010-01-01

    This article presents a revised voxel S values (VSVs) approach for dosimetry in targeted radiotherapy, allowing dose calculation for any voxel size and shape of a given SPECT or PET dataset. This approach represents an update to the methodology presented in MIRD pamphlet no. 17. Methods VSVs were generated in soft tissue with a fine spatial sampling using the Monte Carlo (MC) code MCNPX for particle emissions of 9 radionuclides: 18F, 90Y, 99mTc, 111In, 123I, 131I, 177Lu, 186Re, and 201Tl. A specific resampling algorithm was developed to compute VSVs for desired voxel dimensions. The dose calculation was performed by convolution via a fast Hartley transform. The fine VSVs were calculated for cubic voxels of 0.5 mm for electrons and 1.0 mm for photons. Validation studies were done for 90Y and 131I VSV sets by comparing the revised VSV approach to direct MC simulations. The first comparison included 20 spheres with different voxel sizes (3.8–7.7 mm) and radii (4–64 voxels) and the second comparison a hepatic tumor with cubic voxels of 3.8 mm. MC simulations were done with MCNPX for both. The third comparison was performed on 2 clinical patients with the 3D-RD (3-Dimensional Radiobiologic Dosimetry) software using the EGSnrc (Electron Gamma Shower National Research Council Canada)-based MC implementation, assuming a homogeneous tissue-density distribution. Results For the sphere model study, the mean relative difference in the average absorbed dose was 0.20% ± 0.41% for 90Y and −0.36% ± 0.51% for 131I (n = 20). For the hepatic tumor, the difference in the average absorbed dose to tumor was 0.33% for 90Y and −0.61% for 131I and the difference in average absorbed dose to the liver was 0.25% for 90Y and −1.35% for 131I. The comparison with the 3D-RD software showed an average voxel-to-voxel dose ratio between 0.991 and 0.996. The calculation time was below 10 s with the VSV approach and 50 and 15 h with 3D-RD for the 2 clinical patients. Conclusion This new

  4. Theory, performance, and measured results with an improved absorbed dose water calorimeter. Final report

    SciTech Connect

    Domen, S.T.

    1982-01-01

    The feasibility of this calorimeter is mainly the result of the low thermal diffusivity of water that retards a temperature change at a point along a temperature profile. The temperature change is sensed by two calibrated thermistors sandwiched between two polyethylene films that electrically insulate the thermistors from water. The product of the temperature rise and the specific heat of water gives the combined effect of the absorbed dose and any heat defect. Temperature drifts are quickly controlled by making slight changes in electrical power dissipated in the water. Compared to solid-bodied calorimeters requiring vacuum systems, it was easy to construct, to get into operation, and to operate.

  5. Deterministic absorbed dose estimation in computed tomography using a discrete ordinates method

    SciTech Connect

    Norris, Edward T.; Liu, Xin; Hsieh, Jiang

    2015-07-15

    Purpose: Organ dose estimation for a patient undergoing computed tomography (CT) scanning is very important. Although Monte Carlo methods are considered gold-standard in patient dose estimation, the computation time required is formidable for routine clinical calculations. Here, the authors instigate a deterministic method for estimating an absorbed dose more efficiently. Methods: Compared with current Monte Carlo methods, a more efficient approach to estimating the absorbed dose is to solve the linear Boltzmann equation numerically. In this study, an axial CT scan was modeled with a software package, Denovo, which solved the linear Boltzmann equation using the discrete ordinates method. The CT scanning configuration included 16 x-ray source positions, beam collimators, flat filters, and bowtie filters. The phantom was the standard 32 cm CT dose index (CTDI) phantom. Four different Denovo simulations were performed with different simulation parameters, including the number of quadrature sets and the order of Legendre polynomial expansions. A Monte Carlo simulation was also performed for benchmarking the Denovo simulations. A quantitative comparison was made of the simulation results obtained by the Denovo and the Monte Carlo methods. Results: The difference in the simulation results of the discrete ordinates method and those of the Monte Carlo methods was found to be small, with a root-mean-square difference of around 2.4%. It was found that the discrete ordinates method, with a higher order of Legendre polynomial expansions, underestimated the absorbed dose near the center of the phantom (i.e., low dose region). Simulations of the quadrature set 8 and the first order of the Legendre polynomial expansions proved to be the most efficient computation method in the authors’ study. The single-thread computation time of the deterministic simulation of the quadrature set 8 and the first order of the Legendre polynomial expansions was 21 min on a personal computer

  6. Reduced radiation-absorbed dose to tissues with partial panoramic radiography for evaluation of third molars.

    PubMed

    Kircos, L T; Eakle, W S; Smith, R A

    1986-05-01

    The radiation-absorbed doses from panoramic radiography, distal molar radiography, and a partial panoramic radiographic technique that exposes only the third molar region to radiation are compared. Doses of radiation to the submandibular salivary gland were comparable by all three techniques, but doses of radiation to the head and neck were reduced greatly by the partial panoramic radiographic technique. Partial panoramic radiography is a diagnostically satisfactory and a radiologically safer technique for evaluation of third molar pathosis than is panoramic or distal molar radiography. PMID:3458783

  7. Reduced radiation-absorbed dose to tissues with partial panoramic radiography for evaluation of third molars

    SciTech Connect

    Kircos, L.T.; Eakle, W.S.; Smith, R.A.

    1986-05-01

    The radiation-absorbed doses from panoramic radiography, distal molar radiography, and a partial panoramic radiographic technique that exposes only the third molar region to radiation are compared. Doses of radiation to the submandibular salivary gland were comparable by all three techniques, but doses of radiation to the head and neck were reduced greatly by the partial panoramic radiographic technique. Partial panoramic radiography is a diagnostically satisfactory and a radiologically safer technique for evaluation of third molar pathosis than is panoramic or distal molar radiography.

  8. Thyroid absorbed dose for people at Rongelap, Utirik, and Sifo on March 1, 1954

    SciTech Connect

    Lessard, E.T.; Miltenberger, R.P.; Conrad, R.A.; Musoline, S.V.; Naidu, J.R.; Moorthy, A.; Schopfer, C.J.

    1985-03-01

    A study was undertaken to reexamine thyroid absorbed dose estimates for people accidentally exposed to fallout at Rongelap, Sifo, and Utirik Islands from the Pacific weapon test known as Operation Castle BRAVO. The study included: (1) reevaluation of radiochemical analysis, to relate results from pooled urine to intake, retention, and excretion functions; (2) analysis of neutron-irradiation studies of archival soil samples, to estimate areal activities of the iodine isotopes; (3) analysis of source term, weather data, and meteorological functions used in predicting atmospheric diffusion and fallout deposition, to estimate airborne concentrations of the iodine isotopes; and (4) reevaluation of radioactive fallout, which contaminated a Japanese fishing vessel in the vicinity of Rongelap Island on March 1, 1954, to determine fallout components. The conclusions of the acute exposure study were that the population mean thyroid absorbed doses were 21 gray (2100 rad) at Rongelap, 6.7 gray (670 rad) at Sifo, and 2.8 gray (280 rad) at Utirik. The overall thyroid cancer risk we estimated was in agreement with results published on the Japanese exposed at Nagasaki and Hiroshima. We now postulate that the major route for intake of fallout was by direct ingestion of food prepared and consumed outdoors. 66 refs., 13 figs., 25 tabs.

  9. Verification of absorbed dose using diodes in cobalt-60 radiation therapy.

    PubMed

    Gadhi, Muhammad Asghar; Fatmi, Shahab; Chughtai, Gul M; Arshad, Muhammad; Shakil, Muhammad; Rahmani, Uzma Mahmood; Imran, Malik Younas; Buzdar, Saeed Ahmad

    2016-03-01

    The objective of this work was to enhance the quality and safety of dose delivery in the practice of radiation oncology. To achieve this goal, the absorbed dose verification program was initiated by using the diode in vivo dosimetry (IVD) system (for entrance and exit). This practice was implemented at BINO, Bahawalpur, Pakistan. Diodes were calibrated for making absorbed dose measurements. Various correction factors (SSD, dose non-linearity, field size, angle of incidence, and wedge) were determined for diode IVD system. The measurements were performed in phantom in order to validate the IVD procedure. One hundred and nineteen patients were monitored and 995 measurements were performed. For phantom, the percentage difference between measured and calculated dose for entrance setting remained within ±2% and for exit setting ±3%. For patient measurements, the percentage difference between measured and calculated dose remained within ±5% for entrance/open fields and ±7% for exit/wedge/oblique fields. One hundred and nineteen patients and 995 fields have been monitored during the period of 6 months. The analysis of all available measurements gave a mean percent deviation of ±1.19% and standard deviation of ±2.87%. Larger variations have been noticed in oblique, wedge and exit measurements. This investigation revealed that clinical dosimetry using diodes is simple, provides immediate results and is a useful quality assurance tool for dose delivery. It has enhanced the quality of radiation dose delivery and increased/improved the reliability of the radiation therapy practice in BINO.

  10. ESR spectroscopy for detecting gamma-irradiated dried vegetables and estimating absorbed doses

    NASA Astrophysics Data System (ADS)

    Kwon, Joong-Ho; Chung, Hyung-Wook; Byun, Myung-Woo

    2000-03-01

    In view of an increasing demand for food irradiation technology, the development of a reliable means of detection for the control of irradiated foods has become necessary. Various vegetable food materials (dried cabbage, carrot, chunggyungchae, garlic, onion, and green onion), which can be legally irradiated in Korea, were subjected to a detection study using ESR spectroscopy. Correlation coefficients ( R2) between absorbed doses (2.5-15 kGy) and their corresponding ESR signals were identified from ESR signals. Pre-established threshold values were successfully applied to the detection of 54 coded unknown samples of dried clean vegetables ( chunggyungchae, Brassica camestris var. chinensis), both non-irradiated and irradiated. The ESR signals of irradiated chunggyungchae decreased over a longer storage time, however, even after 6 months of ambient storage, these signals were still distinguishable from those of non-irradiated samples. The most successful estimates of absorbed dose (5 and 8 kGy) were obtained immediately after irradiation using a quadratic fit with average values of 4.85 and 8.65 kGy being calculated.

  11. A geochemical assessment of terrestrial gamma-ray absorbed dose rates.

    PubMed

    Wollenberg, H A; Smith, A R

    1990-02-01

    A survey of the geochemical literature and unpublished data has resulted in the classification of the concentrations of the naturally occurring radioelements U, Th, and K by their associated rock types. A data base of over 2500 entries has been compiled, permitting calculation of terrestrial gamma-ray absorbed dose rates. The general lithology of terrains may be distinguished by their radioelement ratios, relative abundances, and total gamma radioactivities. The gamma-ray absorbed dose rates in air above igneous rocks generally vary with their silica contents, and with the exception of shale, sedimentary rocks have lower K:U and K:Th ratios than most igneous rocks. The appreciable difference between the overall mean terrestrial gamma-ray dose rate for rock of the continental surface (approximately 7 X 10(-8) Gy h-1) and the mean dose rate from field measurements over soil (approximately 5 X 10(-8) Gy h-1) is explained by the substantial differences between radioelement concentrations of soil and rock, differences that may vary markedly with rock type.

  12. Calculated and TLD-based absorbed dose estimates for I-131-labeled 3F8 monoclonal antibody in a human neuroblastoma xenograft nude mouse model.

    PubMed

    Ugur, O; Scott, A M; Kostakoglu, L; Hui, T E; Masterson, M E; Febo, R; Sgouros, G; Rosa, E; Mehta, B M; Fisher, D R

    1995-01-01

    Preclinical evaluation of the therapeutic potential of radiolabeled antibodies is commonly performed in a xenografted nude mouse model. To assess therapeutic efficacy it is important to estimate the absorbed dose to the tumor and normal tissues of the nude mouse. The current study was designed to accurately measure radiation does to human neuroblastoma xenografts and normal organs in nude mice treated with I-131-labeled 3F8 monoclonal antibody (MoAb) against disialoganglioside GD2 antigen. Absorbed dose estimates were obtained using two different approaches: (1) measurement with teflon-imbedded CaSO4:Dy mini-thermoluminescent dosimeters (TLDs) and (2) calculations using mouse S-factors. The calculated total dose to tumor one week after i.v. injection of the 50 microCi I-131-3F8 MoAb was 604 cGy. The corresponding decay corrected and not corrected TLD measurements were 109 +/- 9 and 48.7 +/- 3.4 cGy respectively. The calculated to TLD-derived dose ratios for tumor ranged from 6.1 at 24 h to 5.5 at 1 week. The light output fading rate was found to depend upon the tissue type within which the TLDs were implanted. The decay rate in tumor, muscle, subcutaneous tissue and in vitro, were 9.5, 5.0, 3.7 and 0.67% per day, respectively. We have demonstrated that the type of tissue in which the TLD was implanted strongly influenced the in vivo decay of light output. Even with decay correction, a significant discrepancy was observed between MIRD-based calculated and CaSO4:Dy mini-TLD measured absorbed doses. Batch dependence, pH of the tumor or other variables associated with TLDs which are not as yet well known may account for this discrepancy.

  13. A comparison of depth dependence of dose and linear energy transfer spectra in aluminum and polyethylene

    NASA Technical Reports Server (NTRS)

    Badhwar, G. D.; Cucinotta, F. A.

    2000-01-01

    A set of four tissue-equivalent proportional counters (TEPCs), with their detector heads at the centers of 0 (bare), 3, 7 and 9-inch-diameter aluminum spheres, were flown on Shuttle flight STS-89. Five such detectors at the centers of polyethylene spheres were flown 1 year earlier on STS-81. The results of dose-depth dependence for the two materials convincingly show the merits of using material rich in hydrogen to decrease the radiation exposure to the crew. A comparison of the calculated galactic cosmic radiation (GCR) absorbed dose and dose-equivalent rates using the radiation transport code HZETRN with nuclear fragmentation model NUCFRG2 and the measured GCR absorbed dose rates and dose-equivalent rates shows that they agree within root mean square (rms) error of 12.5 and 8.2%, respectively. However, there are significant depth-dependent differences in the linear energy transfer (LET) spectra. A comparison for trapped protons using the proton transport code BRYNTRN and the AP-8 MIN trapped-proton model shows a systematic bias, with the model underpredicting dose and dose-equivalent rates. These results show the need for improvements in the radiation transport and/or fragmentation models.

  14. Assessment of personnel absorbed dose at production of medical radioisotopes by a cyclotron.

    PubMed

    Sadat-Eshkevar, S M; Karimian, A; Mirzaee, M

    2011-09-01

    The medical radioisotope (201)Tl is produced by a cyclotron through the (203)Tl(p, 3n)(201)Pb reaction in the nuclear medicine research group of Agricultural, Medical and Industrial Research Schools in Iran. The produced (201)Pb decays to (201)Tl by electron capture. One of the most important problems that may occur is malfunction of a part of target or beam line, so that it needs the bombardment to be stopped and the problem fixed. In this work, induced radioactivity of the target, aluminium case of target, beam line and concrete walls of the thallium target room were calculated by Monte Carlo method. Then by using the results of the Monte Carlo simulation, the whole body absorbed dose to cyclotron personnel during repair and after stopping the bombardment, were assessed at different places of target room.

  15. Radiobiologic risk estimation from dental radiology. Part I. Absorbed doses to critical organs

    SciTech Connect

    Underhill, T.E.; Chilvarquer, I.; Kimura, K.; Langlais, R.P.; McDavid, W.D.; Preece, J.W.; Barnwell, G.

    1988-07-01

    The aim of the present study was to generate one consistent set of data for evaluating and comparing radiobiologic risks from different dental radiographic techniques. To accomplish this goal, absorbed doses were measured in fourteen anatomic sites from (1) five different panoramic machines with the use of rare-earth screens, (2) a twenty-film complete-mouth survey with E-speed film, long round cone, (3) a twenty-film complete-mouth survey with E-speed film, long rectangular cone, (4) a four-film interproximal survey with E-speed film, long round cone, and (5) a four-film interproximal survey with E-speed film, long rectangular cone. The dose to the thyroid gland, the active bone marrow, the brain, and the salivary glands was evaluated by means of exposure of a tissue-equivalent phantom, fitted with lithium fluoride thermoluminescent dosimeters (TLDs) at the relevant locations.

  16. Radiobiologic risk estimation from dental radiology. Part I. Absorbed doses to critical organs.

    PubMed

    Underhill, T E; Chilvarquer, I; Kimura, K; Langlais, R P; McDavid, W D; Preece, J W; Barnwell, G

    1988-07-01

    The aim of the present study was to generate one consistent set of data for evaluating and comparing radiobiologic risks from different dental radiographic techniques. To accomplish this goal, absorbed doses were measured in fourteen anatomic sites from (1) five different panoramic machines with the use of rare-earth screens, (2) a twenty-film complete-mouth survey with E-speed film, long round cone, (3) a twenty-film complete-mouth survey with E-speed film, long rectangular cone, (4) a four-film interproximal survey with E-speed film, long round cone, and (5) a four-film interproximal survey with E-speed film, long rectangular cone. The dose to the thyroid gland, the active bone marrow, the brain, and the salivary glands was evaluated by means of exposure of a tissue-equivalent phantom, fitted with lithium fluoride thermoluminescent dosimeters (TLDs) at the relevant locations.

  17. Effect of gamma ray absorbed dose on the FET transistor parameters

    NASA Astrophysics Data System (ADS)

    Eslami, Baharak; Ashrafi, Saleh

    This article tries to explain a modified method on dosimetry, based on electronic solid state including MOSFET (metal oxide semiconductor field effect) transistors. For this purpose, behavior of two models of MOSFETs has been studied as a function of the absorbed dose. The MOSFETs were irradiated at room temperature by 137Cs gamma ray source in the dose range of 1-5 Gy. Threshold voltage variation of investigated samples has been studied based on their transfer characteristic curves (TF) and also using the readout circuit (RC). For evaluation of laboratory samples sensitivity at different operating conditions, different biases were applied on the gate. In practical applications of radiation dosimetry, a significant change occurs in the threshold voltage of irradiated MOSFETs. And sensitivity of these MOSFETs is increased with increasing the bias values. Therefore, these transistors can be excellent candidates as low-cost sensors for systems that are capable of measuring gamma radiation dose.

  18. Absorbed dose distribution visualization for superficial treatments through the Fricke Xylenol Gel dosimeter (FXG)

    NASA Astrophysics Data System (ADS)

    Alva, M.; Sampaio, F. G. A.; Moreira, M. V.; Petchevist, P. C. D.; de Almeida, A.

    2010-11-01

    Electrons, orthovoltage X-rays and betas are used for superficial treatments. It has been shown that it is practical to measure these three types of radiation using gel dosimetry, which is an accurate dosimetric tool, from which one can infer the absorbed dose. The Fricke Xylenol Gel (FXG) dosimeter has presented adequate results due to its spatial resolution, effective atomic number and density that are near to those of soft tissue. The aim of this work is to compare three types of radiation for skin treatments like orthovoltage (X-rays), brachytherapy (beta rays) and megavoltage (electrons) using the FXG-CCD dosimetric system to determine the calibration curves (CC), beam profiles (BP) and percentage depth dose curves (PDD), evidencing why for clinical applications a specific type of radiation is selected for superficial treatment. From the results obtained we can infer that the FXG-CCD system is adequate for linear, area and volume measurements.

  19. Estimation of Organ Absorbed Doses in Patients from 99mTc-diphosphonate Using the Data of MIRDose Software

    PubMed Central

    Shahbazi-Gahrouei, Daryoush; Cheki, Mohsen; Moslehi, Masoud

    2012-01-01

    The purpose of this study was to compare estimation of radiation absorbed doses to patients following bone scans with technetium-99m-labeled methylene diphosphonate (MDP) with the estimates given in MIRDose software. In this study, each patient was injected 25 mCi of 99mTc-MDP. Whole-body images from thirty patients were acquired by gamma camera at 10, 60, 90, 180 minutes after 99mTc-MDP injection. To determine the amount of activity in each organ, conjugate view method was applied on images. MIRD equation was then used to estimate absorbed doses in different organs of patients. At the end, absorbed dose values obtained in this study were compared with the data of MIRDose software. The absorbed doses per unit of injected activity (mGy/MBq × 10–4) for liver, kidneys, bladder wall and spleen were 3.86 ± 1.1, 38.73 ± 4.7, 4.16 ± 1.8 and 3.91 ± 1.3, respectively. The results of this study may be useful to estimate the amount of activity that can be administered to the patient and also showed that methods used in the study for absorbed dose calculation is in good agreement with the data of MIRDose software and it is possible to use by a clinician. PMID:23724374

  20. Verification of absorbed dose using diodes in cobalt-60 radiation therapy.

    PubMed

    Gadhi, Muhammad Asghar; Fatmi, Shahab; Chughtai, Gul M; Arshad, Muhammad; Shakil, Muhammad; Rahmani, Uzma Mahmood; Imran, Malik Younas; Buzdar, Saeed Ahmad

    2016-03-01

    The objective of this work was to enhance the quality and safety of dose delivery in the practice of radiation oncology. To achieve this goal, the absorbed dose verification program was initiated by using the diode in vivo dosimetry (IVD) system (for entrance and exit). This practice was implemented at BINO, Bahawalpur, Pakistan. Diodes were calibrated for making absorbed dose measurements. Various correction factors (SSD, dose non-linearity, field size, angle of incidence, and wedge) were determined for diode IVD system. The measurements were performed in phantom in order to validate the IVD procedure. One hundred and nineteen patients were monitored and 995 measurements were performed. For phantom, the percentage difference between measured and calculated dose for entrance setting remained within ±2% and for exit setting ±3%. For patient measurements, the percentage difference between measured and calculated dose remained within ±5% for entrance/open fields and ±7% for exit/wedge/oblique fields. One hundred and nineteen patients and 995 fields have been monitored during the period of 6 months. The analysis of all available measurements gave a mean percent deviation of ±1.19% and standard deviation of ±2.87%. Larger variations have been noticed in oblique, wedge and exit measurements. This investigation revealed that clinical dosimetry using diodes is simple, provides immediate results and is a useful quality assurance tool for dose delivery. It has enhanced the quality of radiation dose delivery and increased/improved the reliability of the radiation therapy practice in BINO. PMID:26753835

  1. Structural changes caused by radiation-induced reduction and radiolysis: the effect of X-ray absorbed dose in a fungal multicopper oxidase

    SciTech Connect

    De la Mora, Eugenio; Lovett, Janet E.; Blanford, Christopher F.; Garman, Elspeth F.; Valderrama, Brenda; Rudino-Pinera, Enrique

    2012-05-01

    Radiation-induced reduction, radiolysis of copper sites and the effect of pH value together with the concomitant geometrical distortions of the active centres were analysed in several fungal (C. gallica) laccase structures collected at cryotemperature. This study emphasizes the importance of careful interpretation when the crystallographic structure of a metalloprotein is described. X-ray radiation induces two main effects at metal centres contained in protein crystals: radiation-induced reduction and radiolysis and a resulting decrease in metal occupancy. In blue multicopper oxidases (BMCOs), the geometry of the active centres and the metal-to-ligand distances change depending on the oxidation states of the Cu atoms, suggesting that these alterations are catalytically relevant to the binding, activation and reduction of O{sub 2}. In this work, the X-ray-determined three-dimensional structure of laccase from the basidiomycete Coriolopsis gallica (Cg L), a high catalytic potential BMCO, is described. By combining spectroscopic techniques (UV–Vis, EPR and XAS) and X-ray crystallography, structural changes at and around the active copper centres were related to pH and absorbed X-ray dose (energy deposited per unit mass). Depletion of two of the four active Cu atoms as well as low occupancies of the remaining Cu atoms, together with different conformations of the metal centres, were observed at both acidic pH and high absorbed dose, correlating with more reduced states of the active coppers. These observations provide additional evidence to support the role of flexibility of copper sites during O{sub 2} reduction. This study supports previous observations indicating that interpretations regarding redox state and metal coordination need to take radiation effects explicitly into account.

  2. Contrast-enhanced radiotherapy: feasibility and characteristics of the physical absorbed dose distribution for deep-seated tumors

    NASA Astrophysics Data System (ADS)

    Garnica-Garza, H. M.

    2009-09-01

    Radiotherapy using kilovoltage x-rays in conjunction with contrast agents incorporated into the tumor, gold nanoparticles in particular, could represent a potential alternative to current techniques based on high-energy linear accelerators. In this paper, using the voxelized Zubal phantom in conjunction with the Monte Carlo code PENELOPE to model a prostate cancer treatment, it is shown that in combination with a 360° arc delivery technique, tumoricidal doses of radiation can be delivered to deep-seated tumors while still providing acceptable doses to the skin and other organs at risk for gold concentrations in the tumor within the range of 7-10 mg-Au per gram of tissue. Under these conditions and using a x-ray beam with 90% of the fluence within the range of 80-200 keV, a 72 Gy physical absorbed dose to the prostate can be delivered, while keeping the rectal wall, bladder, skin and femoral heads below 65 Gy, 55 Gy, 40 Gy and 30 Gy, respectively. However, it is also shown that non-uniformities in the contrast agent concentration lead to a severe degradation of the dose distribution and that, therefore, techniques to locally quantify the presence of the contrast agent would be necessary in order to determine the incident x-ray fluence that best reproduces the dosimetry obtained under conditions of uniform contrast agent distribution.

  3. Contrast-enhanced radiotherapy: feasibility and characteristics of the physical absorbed dose distribution for deep-seated tumors.

    PubMed

    Garnica-Garza, H M

    2009-09-21

    Radiotherapy using kilovoltage x-rays in conjunction with contrast agents incorporated into the tumor, gold nanoparticles in particular, could represent a potential alternative to current techniques based on high-energy linear accelerators. In this paper, using the voxelized Zubal phantom in conjunction with the Monte Carlo code PENELOPE to model a prostate cancer treatment, it is shown that in combination with a 360 degrees arc delivery technique, tumoricidal doses of radiation can be delivered to deep-seated tumors while still providing acceptable doses to the skin and other organs at risk for gold concentrations in the tumor within the range of 7-10 mg-Au per gram of tissue. Under these conditions and using a x-ray beam with 90% of the fluence within the range of 80-200 keV, a 72 Gy physical absorbed dose to the prostate can be delivered, while keeping the rectal wall, bladder, skin and femoral heads below 65 Gy, 55 Gy, 40 Gy and 30 Gy, respectively. However, it is also shown that non-uniformities in the contrast agent concentration lead to a severe degradation of the dose distribution and that, therefore, techniques to locally quantify the presence of the contrast agent would be necessary in order to determine the incident x-ray fluence that best reproduces the dosimetry obtained under conditions of uniform contrast agent distribution.

  4. SU-F-19A-02: Comparison of Absorbed Dose to Water Standards for HDR Ir-192 Brachytherapy Between the LCR, Brazil and NRC, Canada

    SciTech Connect

    Salata, C; David, M; Almeida, C de; El Gamal, I; Cojocaru, C; Mainegra-Hing, E; McEwen, M

    2014-06-15

    Purpose: To compare absorbed dose to water standards for HDR brachytherapy dosimetry developed by the Radiological Science Laboratory of Rio de Janeiro State University (LCR) and the National Research Council, Canada (NRC). Methods: The two institutions have separately developed absorbed dose standards based on the Fricke dosimetry system. There are important differences between the two standards, including: preparation and read-out of the Fricke solution, irradiation geometry of the Fricke holder in relation to the Ir-192 source, and determination of the G-value to be used at Ir-192 energies. All measurements for both standards were made directly at the NRC laboratory (i.e., no transfer instrument was used) using a single Ir-192 source (microSelectron v2). In addition, the NRC group has established a self-consistent method to determine the G-value for Ir-192, based on an interpolation between G-values obtained at Co-60 and 250kVp X-rays, and this measurement was repeated using the LCR Fricke solution to investigate possible systematic uncertainties. Results: G-values for Co-60 and 250 kVp x-rays, obtained using the LCR Fricke system, agreed with the NRC values within 0.5 % and 1 % respectively, indicating that the general assumption of universal G-values is appropriate in this case. The standard uncertainty in the determination of G for Ir-192 is estimated to be 0.6 %. For the comparison of absorbed dose measurements at the reference point for Ir-192 (1 cm depth in water, perpendicular to the seed long-axis), the ratio Dw(NRC)/Dw(LCR) was found to be 1.011 with a combined standard uncertainty of 1.7 %, k=1. Conclusion: The agreement in the absorbed dose to water values for the LCR and NRC systems is very encouraging. Combined with the lower uncertainty in this approach compared to the present air-kerma approach, these results reaffirm the use of Fricke solution as a potential primary standard for HDR Ir-192 brachytherapy.

  5. SU-F-19A-06: Experimental Investigation of the Energy Dependence of TLD Sensitivity in Low-Energy Photon Beams

    SciTech Connect

    Chen, Z; Nath, R

    2014-06-15

    Purpose: To measure the energy dependence of TLD sensitivity in lowenergy photon beams with equivalent mono-energetic energy matching those of 103Pd, 125I and 131Cs brachytherapy sources. Methods: A Pantek DXT 300 x-ray unit (Precision X-ray, Branford, CT), with stable digital voltage control down to 20 kV, was used to establish three lowenergy photon beams with narrow energy spread and equivalent monoenergetic energies matching those of 103Pd, 125I and 131Cs brachytherapy sources. The low-energy x-ray beams and a reference 6 MV photon beam were calibrated according to the AAPM TG-61 and TG-51 protocols, respectively, using a parallel-plate low-energy chamber and a Farmer cylindrical chamber with NIST traceable calibration factors. The dose response of model TLD-100 micro-cubes (1×1×1 mm{sup 3}) in each beam was measured for five different batches of TLDs (each contained approximately 100 TLDs) that have different histories of irradiation and usage. Relative absorbed dose sensitivity was determined as the quotient of the slope of dose response for a beam-of-interest to that of the reference beam. Results: Equivalent mono-energetic photon energies of the low-energy beams established for 103Pd, 125I and 131Cs sources were 20.5, 27.5, and 30.1 keV, respectively. Each beam exhibited narrow spectral spread with energyhomogeneity index close to 90%. The relative absorbed-dose sensitivity was found to vary between different batches of TLD with maximum differences of up to 8%. The mean and standard deviation determined from the five TLD batches was 1.453 ± 0.026, 1.541 ± 0.035 and 1.529 ± 0.051 for the simulated 103P, 125I and 131Cs beams, respectively. Conclusion: Our measured relative absorbed-dose sensitivities are greater than the historically measured value of 1.41. We find that the relative absorbed-dose sensitivity of TLD in the 103P beam is approximately 5% lower than that of 125I and 131Cs beams. Comparison of our results with other studies will be presented.

  6. Direct determination of the absorbed dose to water from 125I low dose-rate brachytherapy seeds using the new absorbed dose primary standard developed at ENEA-INMRI

    NASA Astrophysics Data System (ADS)

    Toni, M. P.; Pimpinella, M.; Pinto, M.; Quini, M.; Cappadozzi, G.; Silvestri, C.; Bottauscio, O.

    2012-10-01

    Low-intensity radioactive sources emitting low-energy photons are used in the clinic for low dose-rate brachytherapy treatments of tumours. The dosimetry of these sources is based on reference air kerma rate measurements. The absorbed dose rate to water at the reference depth d0 = 1 cm, \\dot {D}_{w,1\\,cm} , is then obtained by a conversion procedure with a large relative standard uncertainty of about 5%. This paper describes a primary standard developed at ENEA-INMRI to directly measure \\dot {D}_{w,1\\,cm} due to LDR sources. The standard is based on a large-angle and variable-volume ionization chamber, embedded in a graphite phantom and operating under ‘wall-less air chamber’ conditions. A set of correction and conversion factors, based on experiments and Monte Carlo simulations, are determined to obtain the value of Dw,1 cm from measurements of increment of ionization current with increasing chamber volume. The relative standard uncertainty on \\dot {D}_{w,1\\,cm} is 2.6%, which is appreciably lower than the current uncertainty. Characteristics of the standard, its associated uncertainty budget, and some experimental results are given for 125I BEBIG I25.S16.C brachytherapy seeds. Finally, results of the experimental determination of the dose-rate constant Λ1 cm, traceable to the Dw,1 cm and the low-energy air kerma ENEA-INMRI standards, are given. The relative standard uncertainty on Λ1 cm is 2.9%, appreciably lower than the typical uncertainty (4.8%) of the values available in the literature.

  7. Comparison of MCNPX and GEANT4 to Predict the Contribution of Non-elastic Nuclear Interactions to Absorbed Dose in Water, PMMA and A150

    SciTech Connect

    Shtejer, K.; Arruda-Neto, J. D. T.; Rodrigues, T. E.; Schulte, R.; Wroe, A.; Menezes, M. O. de; Moralles, M.

    2008-08-11

    Proton induced non-elastic nuclear reactions play an important role in the dose distribution of clinically used proton beams as they deposit dose of high biological effectiveness both within the primary beam path as well as outside the beam to untargeted tissues. Non-elastic nuclear reactions can be evaluated using transport codes based on the Monte Carlo method. In this work, we have utilized the Los Alamos code MCNPX and the CERN GEANT4 toolkit, which are currently the most widely used Monte Carlo programs for proton radiation transport simulations in medical physics, to study the contribution of non-elastic nuclear interactions to the absorbed dose of proton beams in the therapeutic energy range. The impact of different available theoretical models to address the nuclear reaction process was investigated. The contribution of secondary particles from non-elastic nuclear reactions was calculated in three materials relevant in radiotherapy applications: water, PMMA and A150. The results evidence that there are differences in the calculated contribution of the secondary particles heavier than protons to the absorbed dose, with different approaches to model the nuclear reactions. The MCNPX calculation give rise to a larger contribution of d, t, {alpha}{sup 3}He to the total dose compared to the GEANT4 physical models chosen in this work.

  8. A Feasibility Study of Fricke Dosimetry as an Absorbed Dose to Water Standard for 192Ir HDR Sources

    PubMed Central

    deAlmeida, Carlos Eduardo; Ochoa, Ricardo; de Lima, Marilene Coelho; David, Mariano Gazineu; Pires, Evandro Jesus; Peixoto, José Guilherme; Salata, Camila; Bernal, Mario Antônio

    2014-01-01

    High dose rate brachytherapy (HDR) using 192Ir sources is well accepted as an important treatment option and thus requires an accurate dosimetry standard. However, a dosimetry standard for the direct measurement of the absolute dose to water for this particular source type is currently not available. An improved standard for the absorbed dose to water based on Fricke dosimetry of HDR 192Ir brachytherapy sources is presented in this study. The main goal of this paper is to demonstrate the potential usefulness of the Fricke dosimetry technique for the standardization of the quantity absorbed dose to water for 192Ir sources. A molded, double-walled, spherical vessel for water containing the Fricke solution was constructed based on the Fricke system. The authors measured the absorbed dose to water and compared it with the doses calculated using the AAPM TG-43 report. The overall combined uncertainty associated with the measurements using Fricke dosimetry was 1.4% for k = 1, which is better than the uncertainties reported in previous studies. These results are promising; hence, the use of Fricke dosimetry to measure the absorbed dose to water as a standard for HDR 192Ir may be possible in the future. PMID:25521914

  9. A feasibility study of Fricke dosimetry as an absorbed dose to water standard for 192Ir HDR sources.

    PubMed

    deAlmeida, Carlos Eduardo; Ochoa, Ricardo; Lima, Marilene Coelho de; David, Mariano Gazineu; Pires, Evandro Jesus; Peixoto, José Guilherme; Salata, Camila; Bernal, Mario Antônio

    2014-01-01

    High dose rate brachytherapy (HDR) using 192Ir sources is well accepted as an important treatment option and thus requires an accurate dosimetry standard. However, a dosimetry standard for the direct measurement of the absolute dose to water for this particular source type is currently not available. An improved standard for the absorbed dose to water based on Fricke dosimetry of HDR 192Ir brachytherapy sources is presented in this study. The main goal of this paper is to demonstrate the potential usefulness of the Fricke dosimetry technique for the standardization of the quantity absorbed dose to water for 192Ir sources. A molded, double-walled, spherical vessel for water containing the Fricke solution was constructed based on the Fricke system. The authors measured the absorbed dose to water and compared it with the doses calculated using the AAPM TG-43 report. The overall combined uncertainty associated with the measurements using Fricke dosimetry was 1.4% for k = 1, which is better than the uncertainties reported in previous studies. These results are promising; hence, the use of Fricke dosimetry to measure the absorbed dose to water as a standard for HDR 192Ir may be possible in the future. PMID:25521914

  10. Estimation of the absorbed dose in radiation-processed food. 4. EPR measurements on eggshell

    SciTech Connect

    Desrosiers, M.F.; Le, F.G. ); Harewood, P.M.; Josephson, E.S. ); Montesalvo, M. )

    1993-09-01

    Fresh whole eggs treated with ionizing radiation for Salmonellae control testing. The eggshell was then removed and examined by electron paramagnetic resonance (EPR) spectroscopy to determine if EPR could be used to (1) distinguish irradiated from unirradiated eggs and (2) assess the absorbed dose. No EPR signals were detected in unirradiated eggs, while strong signals were measurable for more than 200 days after irradiation. Although a number of EPR signals were measured, the most intense resonance (g = 2.0019) was used for dosimetry throughout the study. This signal was observed to increase linearly with dose (up to [approximately]6 kGy), which decayed [approximately]20% within the first 5 days after irradiation and remained relatively constant thereafter. The standard added-dose method was used to assess, retrospectively, the dose to eggs processed at 0.2, 0.7, and 1.4 kGy. Relatively good results were obtained when measurement was made on the day the shell was reirradiated; with this procedure estimates were better for shell processed at the lower doses.

  11. Fluence-to-absorbed-dose conversion coefficients for neutron beams from 0.001 eV to 100 GeV calculated for a set of pregnant female and fetus models

    NASA Astrophysics Data System (ADS)

    Taranenko, Valery; Xu, X. George

    2008-03-01

    Protection of fetuses against external neutron exposure is an important task. This paper reports a set of absorbed dose conversion coefficients for fetal and maternal organs for external neutron beams using the RPI-P pregnant female models and the MCNPX code. The newly developed pregnant female models represent an adult female with a fetus including its brain and skeleton at the end of each trimester. The organ masses were adjusted to match the reference values within 1%. For the 3 mm cubic voxel size, the models consist of 10-15 million voxels for 35 organs. External monoenergetic neutron beams of six standard configurations (AP, PA, LLAT, RLAT, ROT and ISO) and source energies 0.001 eV-100 GeV were considered. The results are compared with previous data that are based on simplified anatomical models. The differences in dose depend on source geometry, energy and gestation periods: from 20% up to 140% for the whole fetus, and up to 100% for the fetal brain. Anatomical differences are primarily responsible for the discrepancies in the organ doses. For the first time, the dependence of mother organ doses upon anatomical changes during pregnancy was studied. A maximum of 220% increase in dose was observed for the placenta in the nine months model compared to three months, whereas dose to the pancreas, small and large intestines decreases by 60% for the AP source for the same models. Tabulated dose conversion coefficients for the fetus and 27 maternal organs are provided.

  12. Absorbed dose-to-water protocol applied to synchrotron-generated x-rays at very high dose rates

    NASA Astrophysics Data System (ADS)

    Fournier, P.; Crosbie, J. C.; Cornelius, I.; Berkvens, P.; Donzelli, M.; Clavel, A. H.; Rosenfeld, A. B.; Petasecca, M.; Lerch, M. L. F.; Bräuer-Krisch, E.

    2016-07-01

    Microbeam radiation therapy (MRT) is a new radiation treatment modality in the pre-clinical stage of development at the ID17 Biomedical Beamline of the European synchrotron radiation facility (ESRF) in Grenoble, France. MRT exploits the dose volume effect that is made possible through the spatial fractionation of the high dose rate synchrotron-generated x-ray beam into an array of microbeams. As an important step towards the development of a dosimetry protocol for MRT, we have applied the International Atomic Energy Agency’s TRS 398 absorbed dose-to-water protocol to the synchrotron x-ray beam in the case of the broad beam irradiation geometry (i.e. prior to spatial fractionation into microbeams). The very high dose rates observed here mean the ion recombination correction factor, k s , is the most challenging to quantify of all the necessary corrections to apply for ionization chamber based absolute dosimetry. In the course of this study, we have developed a new method, the so called ‘current ramping’ method, to determine k s for the specific irradiation and filtering conditions typically utilized throughout the development of MRT. Using the new approach we deduced an ion recombination correction factor of 1.047 for the maximum ESRF storage ring current (200 mA) under typical beam spectral filtering conditions in MRT. MRT trials are currently underway with veterinary patients at the ESRF that require additional filtering, and we have estimated a correction factor of 1.025 for these filtration conditions for the same ESRF storage ring current. The protocol described herein provides reference dosimetry data for the associated Treatment Planning System utilized in the current veterinary trials and anticipated future human clinical trials.

  13. Absorbed dose-to-water protocol applied to synchrotron-generated x-rays at very high dose rates.

    PubMed

    Fournier, P; Crosbie, J C; Cornelius, I; Berkvens, P; Donzelli, M; Clavel, A H; Rosenfeld, A B; Petasecca, M; Lerch, M L F; Bräuer-Krisch, E

    2016-07-21

    Microbeam radiation therapy (MRT) is a new radiation treatment modality in the pre-clinical stage of development at the ID17 Biomedical Beamline of the European synchrotron radiation facility (ESRF) in Grenoble, France. MRT exploits the dose volume effect that is made possible through the spatial fractionation of the high dose rate synchrotron-generated x-ray beam into an array of microbeams. As an important step towards the development of a dosimetry protocol for MRT, we have applied the International Atomic Energy Agency's TRS 398 absorbed dose-to-water protocol to the synchrotron x-ray beam in the case of the broad beam irradiation geometry (i.e. prior to spatial fractionation into microbeams). The very high dose rates observed here mean the ion recombination correction factor, k s , is the most challenging to quantify of all the necessary corrections to apply for ionization chamber based absolute dosimetry. In the course of this study, we have developed a new method, the so called 'current ramping' method, to determine k s for the specific irradiation and filtering conditions typically utilized throughout the development of MRT. Using the new approach we deduced an ion recombination correction factor of 1.047 for the maximum ESRF storage ring current (200 mA) under typical beam spectral filtering conditions in MRT. MRT trials are currently underway with veterinary patients at the ESRF that require additional filtering, and we have estimated a correction factor of 1.025 for these filtration conditions for the same ESRF storage ring current. The protocol described herein provides reference dosimetry data for the associated Treatment Planning System utilized in the current veterinary trials and anticipated future human clinical trials. PMID:27366861

  14. EPR dosimetry of cortical bone and tooth enamel irradiated with X and gamma rays: Study of energy dependence

    SciTech Connect

    Schauer, D.A.; Links, J.M. ); Desrosiers, M.F.; Le, F.G.; Seltzer, S.M. )

    1994-04-01

    Previous investigators have reported that the radiation-induced EPR signal intensity in compact or cortical bone increases up to a factor of two with decreasing photon energy for a given absorbed dose. If the EPR signal intensity was dependent on energy, it could limit the application of EPR spectrometry and the additive reirradiation method to obtain dose estimates. We have recently shown that errors in the assumptions governing conversion of measured exposure to absorbed dose can lead to similar [open quotes]apparent[close quotes] energy-dependence results. We hypothesized that these previous results were due to errors in the estimated dose in bone, rather than the effects of energy dependence per se. To test this hypothesis we studied human adult cortical bone from male and female donors ranging in age from 23 to 95 years, and bovine tooth enamel, using 34 and 138 keV average energy X-ray beams and [sup 137]Cs (662 keV) and [sup 60]Co (1250 keV) [gamma] rays. In a femur from a 47-year-old male (subject 1), there was a difference of borderline significance at the [alpha] = 0.05 level in the mean radiation-induced hydroxyapatite signal intensities as a function of photon energy. No other statistically significant differences in EPR signal intensity as a function of photon energy were observed in this subject, or in the tibia from a 23-year-old male (subject 2) and the femur from a 75-year-old female (subject 3). However, there was a trend toward a decrease (12-15%) in signal intensity at the lowest energy compared with the highest energy in subjects 1 and 3. Further analysis of the data from subject 1 revealed that this trend, which is in the opposite direction of previous reports but is consistent with theory, is statistically significant. There were no efforts of energy dependence in the tooth samples. 16 refs., 7 figs., 5 tabs.

  15. Pain and Mean Absorbed Dose to the Pubic Bone After Radiotherapy Among Gynecological Cancer Survivors

    SciTech Connect

    Waldenstroem, Ann-Charlotte; Olsson, Caroline; Wilderaeng, Ulrica; Dunberger, Gail; Lind, Helena; Al-Abany, Massoud; Palm, Asa; Avall-Lundqvist, Elisabeth; Johansson, Karl-Axel; Steineck, Gunnar

    2011-07-15

    Purpose: To analyze the relationship between mean absorbed dose to the pubic bone after pelvic radiotherapy for gynecological cancer and occurrence of pubic bone pain among long-term survivors. Methods and Materials: In an unselected, population-based study, we identified 823 long-term gynecological cancer survivors treated with pelvic radiotherapy during 1991-2003. For comparison, we used a non-radiation-treated control population of 478 matched women from the Swedish Population Register. Pain, intensity of pain, and functional impairment due to pain in the pubic bone were assessed with a study-specific postal questionnaire. Results: We analyzed data from 650 survivors (participation rate 79%) with median follow-up of 6.3 years (range, 2.3-15.0 years) along with 344 control women (participation rate, 72 %). Ten percent of the survivors were treated with radiotherapy; ninety percent with surgery plus radiotherapy. Brachytherapy was added in 81%. Complete treatment records were recovered for 538/650 survivors, with dose distribution data including dose-volume histograms over the pubic bone. Pubic bone pain was reported by 73 survivors (11%); 59/517 (11%) had been exposed to mean absorbed external beam doses <52.5 Gy to the pubic bone and 5/12 (42%) to mean absorbed external beam doses {>=}52.5 Gy. Thirty-three survivors reported pain affecting sleep, a 13-fold increased prevalence compared with control women. Forty-nine survivors reported functional impairment measured as pain walking indoors, a 10-fold increased prevalence. Conclusions: Mean absorbed external beam dose above 52.5 Gy to the pubic bone increases the occurrence of pain in the pubic bone and may affect daily life of long-term survivors treated with radiotherapy for gynecological cancer.

  16. Influence of lead apron shielding on absorbed doses from panoramic radiography

    PubMed Central

    Rottke, D; Grossekettler, L; Sawada, K; Poxleitner, P; Schulze, D

    2013-01-01

    Objectives: This study investigated the absorbed doses in a full anthropomorphic body phantom from two different panoramic radiography devices, performing protocols with and without applying a lead apron. Methods: A RANDO® full body phantom (Alderson Research Laboratories Inc., Stamford, CT) was equipped with 110 thermoluminescent dosemeters at 55 different sites and set up in two different panoramic radiography devices [SCANORA® three-dimensional (3D) (SOREDEX, Tuusula, Finland) and ProMax® 3D (Planmeca, Helsinki, Finland)] and exposed. Two different protocols were performed in the two devices. The first protocol was performed without any lead shielding, whereas the phantom was equipped with a standard adult lead apron for the second protocol. Results: A two-tailed paired samples t-test for the SCANORA 3D revealed that there is no difference between the protocol using lead apron shielding (m = 87.99, s = 102.98) and the protocol without shielding (m = 87.34, s = 107.49), t(54) = −0.313, p > 0.05. The same test for the ProMax 3D showed that there is also no difference between the protocol using shielding (m = 106.48, s = 117.38) and the protocol without shielding (m = 107.75, s = 114,36), t(54) = 0.938, p > 0.05. Conclusions: In conclusion, the results of this study showed no statistically significant differences between a panoramic radiography with or without the use of lead apron shielding. PMID:24174012

  17. SU-FF-T-390: In-Vivo Prostate Brachytherapy Absorbed Dose Measurements

    SciTech Connect

    Gueye, Paul; Velasco, Carlos; Keppel, Cynthia; Murphy, B; Sinesi, C

    2009-06-01

    Purpose: In-vivo prostate brachytherapy absorbed dosimetrydetector using scintillating fibers. Method and Materials: Five pairs of 85.5 {+-} 0.05 cm long blue shifted scintillating fibers (model BCF-10) with 1 mm{sup 2} cross sectional area were placed in a mixture of gelatin (368.6 {+-} 0.5 grams) and water (3.78 {+-} 0.025 liters) to measured the absorbed dose delivered by a 12 Ci {sup 192}Ir HDR source. The fibers were held by a 7 x 7 cm{sup 2} template grid and optically connected to a 16-channel multianode photomultiplier tube (Hamamatsu, model H6568). Each pair consisted of one fiber 4 mm shorter than the other one to extract the dose by the subtraction method. A dose atlas was used for radiation delivered to the phantom. The plans followed delivered 5 and 7 Gy to a point located 2.0 centimeters away from the central dwelling positions. A total of 32 data points were acquired in a plan to assess the linearity and reproducibility of the measurements.Results: Reproducibility of the data was found to be within 5% and the overall accuracy of the system estimated to be {+-}5.5%. The linearity of the data for all 7 measureddose values (ranging from 0.6 to 7 Gy), gives a slope of 312 counts/Gy with a 1.4% relative deviation. Conclusion: This work indicates the possibility of measuring in real-time the dose effectively delivered to a biological system during prostate brachytherapy treatments. The availability of commercially thin (150 {micro}m) scintillating fibers opens the capability of using such system during clinical treatments (by embedding the fibers within the catheters) with the advantage of performing real-time adjustment of the dose delivery.

  18. Magnetic Resonance Imaging-Based Radiation-Absorbed Dose Estimation of {sup 166}Ho Microspheres in Liver Radioembolization

    SciTech Connect

    Seevinck, Peter R.; Maat, Gerrit H. van de; Wit, Tim C. de; Vente, Maarten A.D.; Nijsen, Johannes F.W.; Bakker, Chris J.G.

    2012-07-01

    Purpose: To investigate the potential of magnetic resonance imaging (MRI) for accurate assessment of the three-dimensional {sup 166}Ho activity distribution to estimate radiation-absorbed dose distributions in {sup 166}Ho-loaded poly (L-lactic acid) microsphere ({sup 166}Ho-PLLA-MS) liver radioembolization. Methods and Materials: MRI, computed tomography (CT), and single photon emission CT (SPECT) experiments were conducted on an anthropomorphic gel phantom with tumor-simulating gel samples and on an excised human tumor-bearing liver, both containing known amounts of {sup 166}Ho-PLLA-MS. Three-dimensional radiation-absorbed dose distributions were estimated at the voxel level by convolving the {sup 166}Ho activity distribution, derived from quantitative MRI data, with a {sup 166}Ho dose point-kernel generated by MCNP (Monte Carlo N-Particle transport code) and from Medical Internal Radiation Dose Pamphlet 17. MRI-based radiation-absorbed dose distributions were qualitatively compared with CT and autoradiography images and quantitatively compared with SPECT-based dose distributions. Both MRI- and SPECT-based activity estimations were validated against dose calibrator measurements. Results: Evaluation on an anthropomorphic phantom showed that MRI enables accurate assessment of local {sup 166}Ho-PLLA-MS mass and activity distributions, as supported by a regression coefficient of 1.05 and a correlation coefficient of 0.99, relating local MRI-based mass and activity calculations to reference values obtained with a dose calibrator. Estimated MRI-based radiation-absorbed dose distributions of {sup 166}Ho-PLLA-MS in an ex vivo human liver visually showed high correspondence to SPECT-based radiation-absorbed dose distributions. Quantitative analysis revealed that the differences in local and total amounts of {sup 166}Ho-PLLA-MS estimated by MRI, SPECT, and the dose calibrator were within 10%. Excellent agreement was observed between MRI- and SPECT-based dose

  19. An estimate by two methods of thyroid absorbed doses due to BRAVO fallout in several northern Marshall Islands

    SciTech Connect

    Musolino, S.V.; Hull, A.P.; Greenhouse, N.A.

    1997-10-01

    Estimates of the thyroid absorbed doses due to fallout originating from the 1 March 1954 BRAVO thermonuclear test on Bikini Atoll have been made for several inhabited locations in the Northern Marshall Islands. Rongelap, Utirik, Rongerik and Ailinginae Atolls were also inhabited on 1 March 1954, where retrospective thyroid absorbed doses have previously been reconstructed. Current estimates are based primarily on external exposure data, which were recorded shortly after each nuclear test in the Castle Series, and secondarily on soil concentrations of {sup 137}Cs in samples collected in 1978 and 1988, along with aerial monitoring done in 1978. External exposures and {sup 137}Cs Soil concentrations were representative of the atmospheric transport and deposition patterns of the entire Castle Series tests and show that the BRAVO test was the major contributor to fallout exposure during the Castle series and other test series which were carried out in the Marshall Islands. These data have been used as surrogates for fission product radioiodines and telluriums in order to estimate the range of thyroid absorbed doses that may have occurred throughout the Marshall Islands. Dosimetry based on these two sets of estimates agreed within a factor of 4 at the locations where BRAVO was the dominant contributor to the total exposure and deposition. Both methods indicate that thyroid absorbed doses in the range of 1 Gy (100 rad) may have been incurred in some of the northern locations, whereas the doses at southern locations did not significantly exceed levels comparable to those from worldwide fallout. The results of these estimates indicate that a systematic medical survey for thyroid disease should be conducted, and that a more definitive dose reconstruction should be made for all the populated atolls and islands in the Northern Marshall Islands beyond Rongelap, Utirik, Rongerik and Ailinginae, which were significantly contaminated by BRAVO fallout. 30 refs., 2 figs., 10 tabs.

  20. Development of a water calorimetry-based standard for absorbed dose to water in HDR {sup 192}Ir brachytherapy

    SciTech Connect

    Sarfehnia, Arman; Seuntjens, Jan

    2010-04-15

    Purpose: The aim of this article is to develop and evaluate a primary standard for HDR {sup 192}Ir brachytherapy based on 4 deg. C stagnant water calorimetry. Methods: The absolute absorbed dose to water was directly measured for several different Nucletron microSelectron {sup 192}Ir sources of air kerma strength ranging between 21 000 and 38 000 U and for source-to-detector separations ranging between 25 and 70 mm. The COMSOL MULTIPHYSICS software was used to accurately calculate the heat transport in a detailed model geometry. Through a coupling of the ''conduction and convection'' module with the ''Navier-Stokes incompressible fluid'' module in the software, both the conductive and convective effects were modeled. Results: A detailed uncertainty analysis resulted in an overall uncertainty in the absorbed dose of 1.90%(1{sigma}). However, this includes a 1.5% uncertainty associated with a nonlinear predrift correction which can be substantially reduced if sufficient time is provided for the system to come to a new equilibrium in between successive calorimetric runs, an opportunity not available to the authors in their clinical setting due to time constraints on the machine. An average normalized dose rate of 361{+-}7 {mu}Gy/(h U) at a source-to-detector separation of 55 mm was measured for the microSelectron {sup 192}Ir source based on water calorimetry. The measured absorbed dose per air kerma strength agreed to better than 0.8%(1{sigma}) with independent ionization chamber and EBT-1 Gafchromic film reference dosimetry as well as with the currently accepted AAPM TG-43 protocol measurements. Conclusions: This work paves the way toward a primary absorbed dose to water standard in {sup 192}Ir brachytherapy.

  1. Visible photoluminescence of color centers in LiF crystals for absorbed dose evaluation in clinical dosimetry

    NASA Astrophysics Data System (ADS)

    Villarreal-Barajas, J. E.; Piccinini, M.; Vincenti, M. A.; Bonfigli, F.; Khan, R. F.; Montereali, R. M.

    2015-04-01

    Among insulating materials, lithium fluoride (LiF) has been successfully used as ionizing radiation dosemeter for more than 60 years. Thermoluminescence (TL) has been the most commonly used reading technique to evaluate the absorbed dose. Lately, optically stimulated luminescence (OSL) of visible emitting color centers (CCs) has also been explored in pure and doped LiF. This work focuses on the experimental behaviour of nominally pure LiF crystals dosemeters for 6 MV x rays at low doses based on photoluminescence (PL) of radiation induced CCs. Polished LiF crystals were irradiated using 6 MV x rays produced by a clinical linear accelerator. The doses (absorbed dose to water) covered the 1-100 Gy range. Optical absorption spectra show stable formation of primary F defects up to a maximum concentration of 2×1016 cm-3, while no significant M absorption band at around 450 nm was detected. On the other hand, under Argon laser excitation at 458 nm, PL spectra of the irradiated LiF crystals clearly exhibited the characteristic F2 and F+3 visible broad emission bands. Their sum intensity is linearly proportional to the absorbed dose in the investigated range. PL integrated intensity was also measured using a conventional fluorescence optical microscope under blue lamp illumination. The relationship between the absorbed dose and the integrated F2 and F+3 PL intensities, represented by the net average pixel number in the optical fluorescence images, is also fairly linear. Even at the low point defect densities obtained at the investigated doses, these preliminary experimental results are encouraging for further investigation of CCs PL in LiF crystals for clinical dosimetry.

  2. Radiation absorbed dose estimates for oxygen-15 radiopharmaceuticals (H2( V)O, C VO, O VO) in newborn infants

    SciTech Connect

    Powers, W.J.; Stabin, M.; Howse, D.; Eichling, J.O.; Herscovitch, P.

    1988-12-01

    In preparation for measurement of regional cerebral oxygen metabolism by positron emission tomography, radiation absorbed dose estimates for 19 internal organs, blood, and total body were calculated for newborn infants following bolus intravenous administration of H2( V)O and brief inhalation of C VO and O VO. Cumulated activity for each radiopharmaceutical was calculated from a compartmental model based on the known biologic behavior of the compound. Values for mean absorbed dose/unit cumulated activity (S) for internal organs and total body were based on a newborn phantom. S was separately calculated for blood. Total radiopharmaceutical absorbed dose estimates necessary to measure cerebral oxygen metabolism in a 3.51-kg infant based on 0.7 mCi/kg H2( V)O and 1 mCi/kg C VO and O VO were determined to be 1.6 rad to the lung (maximum organ dose), 0.28 rad to the marrow, 0.46 rad to the gonads, and 0.22 rad to total body. These values are similar to those for current clinical nuclear medicine procedures employing /sup 99m/Tc in newborn infants.

  3. Use of Monte Carlo simulations with a realistic rat phantom for examining the correlation between hematopoietic system response and red marrow absorbed dose in Brown Norway rats undergoing radionuclide therapy with {sup 177}Lu- and {sup 90}Y-BR96 mAbs

    SciTech Connect

    Larsson, Erik; Ljungberg, Michael; Martensson, Linda; Nilsson, Rune; Tennvall, Jan; Strand, Sven-Erik; Joensson, Bo-Anders

    2012-07-15

    Purpose: Biokinetic and dosimetry studies in laboratory animals often precede clinical radionuclide therapies in humans. A reliable evaluation of therapeutic efficacy is essential and should be based on accurate dosimetry data from a realistic dosimetry model. The aim of this study was to develop an anatomically realistic dosimetry model for Brown Norway rats to calculate S factors for use in evaluating correlations between absorbed dose and biological effects in a preclinical therapy study. Methods: A realistic rat phantom (Roby) was used, which has some flexibility that allows for a redefinition of organ sizes. The phantom was modified to represent the anatomic geometry of a Brown Norway rat, which was used for Monte Carlo calculations of S factors. Kinetic data for radiolabeled BR96 monoclonal antibodies were used to calculate the absorbed dose. Biological data were gathered from an activity escalation study with {sup 90}Y- and {sup 177}Lu-labeled BR96 monoclonal antibodies, in which blood cell counts and bodyweight were examined up to 2 months follow-up after injection. Reductions in white blood cell and platelet counts and declines in bodyweight were quantified by four methods and compared to the calculated absorbed dose to the bone marrow or the total body. Results: A red marrow absorbed dose-dependent effect on hematological parameters was observed, which could be evaluated by a decrease in blood cell counts. The absorbed dose to the bone marrow, corresponding to the maximal tolerable activity that could safely be administered, was determined to 8.3 Gy for {sup 177}Lu and 12.5 Gy for {sup 90}Y. Conclusions: There was a clear correlation between the hematological effects, quantified with some of the studied parameters, and the calculated red marrow absorbed doses. The decline in body weight was stronger correlated to the total body absorbed dose, rather than the red marrow absorbed dose. Finally, when considering a constant activity concentration, the phantom

  4. The energy dependence and dose response of a commercial optically stimulated luminescent detector for kilovoltage photon, megavoltage photon, and electron, proton, and carbon beams

    SciTech Connect

    Reft, Chester S.

    2009-05-15

    Optically stimulated luminescent detectors, which are widely used in radiation protection, offer a number of potential advantages for application in radiation therapy dosimetry. Their introduction into this field has been somewhat hampered by the lack of information on their radiation response in megavoltage beams. Here the response of a commercially available optically stimulated luminescent detector (OSLD) is determined as a function of energy, absorbed dose to water, and linear energy transfer (LET). The detector response was measured as a function of energy for absorbed doses from 0.5 to 4.0 Gy over the following ranges: 125 kVp to18 MV for photons, 6-20 MeV for electrons, 50-250 MeV for protons, and 290 MeV/u for the carbon ions. For the low LET beams, the response of the detector was linear up to 2 Gy with supralinearity occurring at higher absorbed doses. For the kilovoltage photons, the detector response relative to 6 MV increased with decreasing energy due to the higher atomic number of aluminum oxide (11.2) relative to water (7.4). For the megavoltage photons and electrons, the response was independent of energy. The response for protons was also independent of energy, but it was about 6% higher than its response to 6 MV photons. For the carbon ions, the dose response was linear for a given LET from 0.5 to 4.0 Gy, and no supralinearity was observed. However, it did exhibit LET dependence on the response relative to 6 MV photons decreasing from 1.02 at 1.3 keV/{mu}m to 0.41 at 78 keV/{mu}m. These results provide additional information on the dosimetric properties for this particular OSL detector and also demonstrate the potential for their use in photon, electron, and proton radiotherapy dosimetry with a more limited use in high LET radiotherapy dosimetry.

  5. Human absorbed dose estimation for a new (175)Yb-phosphonate based on rats data: Comparison with similar bone pain palliation agents.

    PubMed

    Vaez-Tehrani, Mahdokht; Zolghadri, Samaneh; Yousefnia, Hassan; Afarideh, Hossein

    2016-09-01

    In this work, the absorbed dose to human organs for (175)Yb-BPAMD was evaluated based on the biodistribution studies in rats. The results showed that the bone surface would receive the highest absorbed dose after injection of (175)Yb-BPAMD with 13.32mGy/MBq, while the other organs receive insignificant absorbed dose. Also, the comparison of (175)Yb-BPAMD with other therapeutic phosphonate complexes demonstrated noticeable characteristics for this new agent. Generally, based on the obtained results, (175)Yb-BPAMD can be considered as a promising agent for bone pain palliative therapy in near future. PMID:27337650

  6. Absorbed dose measurements for kV-cone beam computed tomography in image-guided radiation therapy

    NASA Astrophysics Data System (ADS)

    Hioki, Kazunari; Araki, Fujio; Ohno, Takeshi; Nakaguchi, Yuji; Tomiyama, Yuuki

    2014-12-01

    In this study, we develope a novel method to directly evaluate an absorbed dose-to-water for kilovoltage-cone beam computed tomography (kV-CBCT) in image-guided radiation therapy (IGRT). Absorbed doses for the kV-CBCT systems of the Varian On-Board Imager (OBI) and the Elekta X-ray Volumetric Imager (XVI) were measured by a Farmer ionization chamber with a 60Co calibration factor. The chamber measurements were performed at the center and four peripheral points in body-type (30 cm diameter and 51 cm length) and head-type (16 cm diameter and 33 cm length) cylindrical water phantoms. The measured ionization was converted to the absorbed dose-to-water by using a 60Co calibration factor and a Monte Carlo (MC)-calculated beam quality conversion factor, kQ, for 60Co to kV-CBCT. The irradiation for OBI and XVI was performed with pelvis and head modes for the body- and the head-type phantoms, respectively. In addition, the dose distributions in the phantom for both kV-CBCT systems were calculated with MC method and were compared with measured values. The MC-calculated doses were calibrated at the center in the water phantom and compared with measured doses at four peripheral points. The measured absorbed doses at the center in the body-type phantom were 1.96 cGy for OBI and 0.83 cGy for XVI. The peripheral doses were 2.36-2.90 cGy for OBI and 0.83-1.06 cGy for XVI. The doses for XVI were lower up to approximately one-third of those for OBI. Similarly, the measured doses at the center in the head-type phantom were 0.48 cGy for OBI and 0.21 cGy for XVI. The peripheral doses were 0.26-0.66 cGy for OBI and 0.16-0.30 cGy for XVI. The calculated peripheral doses agreed within 3% in the pelvis mode and within 4% in the head mode with measured doses for both kV-CBCT systems. In addition, the absorbed dose determined in this study was approximately 4% lower than that in TG-61 but the absorbed dose by both methods was in agreement within their combined

  7. Comparison of mathematical models for red marrow and blood absorbed dose estimation in the radioiodine treatment of advanced differentiated thyroid carcinoma

    NASA Astrophysics Data System (ADS)

    Miranti, A.; Giostra, A.; Richetta, E.; Gino, E.; Pellerito, R. E.; Stasi, M.

    2015-02-01

    Metastatic and recurrent differentiated thyroid carcinoma is preferably treated with 131I, whose administered activity is limited by red marrow (RM) toxicity, originally correlated by Benua to a blood absorbed dose higher than 2 Gy. Afterward a variety of dosimetric approaches has been proposed. The aim of this work is to compare the results of the Benua formula with the ones of other three blood and RM absorbed dose formulae. Materials and methods have been borrowed by the dosimetric protocol of the Italian Internal Dosimetry group and adapted to the routine of our centre. Wilcoxon t-tests and percentage differences have been applied for comparison purposes. Results are significantly different (p < 0.05) from each other, with an average percentage difference between Benua versus other results of -22%. The dosimetric formula applied to determine blood or RM absorbed dose may contribute significantly to increase heterogeneity in absorbed dose and dose-response results. Standardization should be a major objective.

  8. The changes in optical absorbance of ZrO2 thin film with the rise of the absorbed dose

    NASA Astrophysics Data System (ADS)

    Abayli, D.; Baydogan, N.

    2016-03-01

    In this study, zirconium oxide (ZrO2) thin film samples prepared by sol-gel method were irradiated using Co-60 radioisotope as gamma source. Then, it was investigated the ionizing effect on optical properties of ZrO2 thin film samples with the rise of the absorbed dose. The changes in the optical absorbance of ZrO2 thin films were determined by using optical transmittance and the reflectance measurements in the range between 190 - 1100 nm obtained from PG Instruments T80 UV-Vis spectrophotometer.

  9. Calculation of. beta. -ray absorbed dose rate for /sup 131/I applied to the inflorescence of Tradescantia

    SciTech Connect

    Bingo, K.; Tano, S.; Numakunai, T.; Yoshida, Y.; Yamaguchi, H.

    1981-03-01

    Effects of /sup 131/I applied to the inflorescence on the induction of somatic mutations in Tradescantia stamen hairs were previously investigated, and the doubling dose (activity) was estimated to be 4 nCi. In the present paper, the absorbed dose rate in stamen hairs of Tradescantia for ..beta.. rays from the applied /sup 131/I was calculated. The doubling dose for the /sup 131/I (4 nCi) applied to the inflorescence was estimated to be higher than 0.3 rad (assuming uniform distribution of /sup 131/I on the surface of the buds and assuming that the shape of the buds was a sphere) and lower than 1.0 rad.

  10. Influence of the characteristic curve on the clinical image quality and patient absorbed dose in lumbar spine radiography

    NASA Astrophysics Data System (ADS)

    Tingberg, Anders; Herrmann, Clemens; Lanhede, Birgitta; Almen, Anja; Mattsson, Saron; Panzer, Werner; Besjakov, Jack; Mansson, Lars G.; Kheddache, Susanne; Zankl, Maria

    2001-06-01

    The 'European Guidelines on Quality Criteria for Diagnostic Radiographic Images' do not address the choice of film characteristic (H/D) curve, which is an important parameter for the description of a radiographic screen-film system. Since it is not possible to investigate this influence by taking repeated exposures of the same patients on films with systematically varied H/D curves, patient images of lumbar spine were digitised in the current study. The image contrast was altered by digital image processing techniques, simulating images with H/D curves varying from flat over standard latitude to a film type steeper than a mammography film. The manipulated images were printed on film for evaluation. Seven European radiologists evaluated the clinical image quality of in total 224 images by analysing the fulfilment of the European Image Criteria and by visual grading analysis of the images. The results show that the local quality can be significantly improved by the application of films with a steeper film H/D curve compared to the standard latitude film. For images with an average optical density of about 1.25, the application of the steeper film results in a reduction of patient absorbed dose by about 10-15% without a loss of diagnostically relevant image information. The results also show that the patient absorbed dose reduction obtained by altering the tube voltage from 70 kV to 90 kV coincides with a loss of image information that cannot be compensated for by simply changing the shape of the H/D curve.

  11. Determination of the Absorbed Dose Rate to Water for the 18-mm Helmet of a Gamma Knife

    SciTech Connect

    Chung, Hyun-Tai; Park, Youngho; Hyun, Sangil; Choi, Yongsoo; Kim, Gi Hong; Kim, Dong Gyu; Chun, Kook Jin

    2011-04-01

    Purpose: To measure the absorbed dose rate to water of {sup 60}Co gamma rays of a Gamma Knife Model C using water-filled phantoms (WFP). Methods and Materials: Spherical WFP with an equivalent water depth of 5, 7, 8, and 9 cm were constructed. The dose rates at the center of an 18-mm helmet were measured in an 8-cm WFP (WFP-3) and two plastic phantoms. Two independent measurement systems were used: one was calibrated to an air kerma (Set I) and the other was calibrated to the absorbed dose to water (Set II). The dose rates of WFP-3 and the plastic phantoms were converted to dose rates for an 8-cm water depth using the attenuation coefficient and the equivalent water depths. Results: The dose rate measured at the center of WFP-3 using Set II was 2.2% and 1.0% higher than dose rates measured at the center of the two plastic phantoms. The measured effective attenuation coefficient of Gamma Knife photon beam in WFPs was 0.0621 cm{sup -1}. After attenuation correction, the difference between the dose rate at an 8-cm water depth measured in WFP-3 and dose rates in the plastic phantoms was smaller than the uncertainty of the measurements. Conclusions: Systematic errors related to the characteristics of the phantom materials in the dose rate measurement of a Gamma Knife need to be corrected for. Correction of the dose rate using an equivalent water depth and attenuation provided results that were more consistent.

  12. Mean Absorbed Dose to the Anal-Sphincter Region and Fecal Leakage among Irradiated Prostate Cancer Survivors

    SciTech Connect

    Alsadius, David; Hedelin, Maria; Lundstedt, Dan; Pettersson, Niclas; Wilderaeng, Ulrica; Steineck, Gunnar

    2012-10-01

    Purpose: To supplement previous findings that the absorbed dose of ionizing radiation to the anal sphincter or lower rectum affects the occurrence of fecal leakage among irradiated prostate-cancer survivors. We also wanted to determine whether anatomically defining the anal-sphincter region as the organ at risk could increase the degree of evidence underlying clinical guidelines for restriction doses to eliminate this excess risk. Methods and Materials: We identified 985 men irradiated for prostate cancer between 1993 and 2006. In 2008, we assessed long-term gastrointestinal symptoms among these men using a study-specific questionnaire. We restrict the analysis to the 414 men who had been treated with external beam radiation therapy only (no brachytherapy) to a total dose of 70 Gy in 2-Gy daily fractions to the prostate or postoperative prostatic region. On reconstructed original radiation therapy dose plans, we delineated the anal-sphincter region as an organ at risk. Results: We found that the prevalence of long-term fecal leakage at least once per month was strongly correlated with the mean dose to the anal-sphincter region. Examining different dose intervals, we found a large increase at 40 Gy; {>=}40 Gy compared with <40 Gy gave a prevalence ratio of 3.8 (95% confidence interval 1.6-8.6). Conclusions: This long-term study shows that mean absorbed dose to the anal-sphincter region is associated with the occurrence of long-term fecal leakage among irradiated prostate-cancer survivors; delineating the anal-sphincter region separately from the rectum and applying a restriction of a mean dose <40 Gy will, according to our data, reduce the risk considerably.

  13. Simulation and Measurement of Absorbed Dose from 137 Cs Gammas Using a Si Timepix Detector

    NASA Technical Reports Server (NTRS)

    Stoffle, Nicholas; Pinsky, Lawrence; Empl, Anton; Semones, Edward

    2011-01-01

    The TimePix readout chip is a hybrid pixel detector with over 65k independent pixel elements. Each pixel contains its own circuitry for charge collection, counting logic, and readout. When coupled with a Silicon detector layer, the Timepix chip is capable of measuring the charge, and thus energy, deposited in the Silicon. Measurements using a NIST traceable 137Cs gamma source have been made at Johnson Space Center using such a Si Timepix detector, and this data is compared to simulations of energy deposition in the Si layer carried out using FLUKA.

  14. PLATIN (plant-atmosphere interaction) I: A model of plant-atmosphere interaction for estimating absorbed doses of gaseous air pollutants.

    PubMed

    Grünhage, L; Haenel, H D

    1997-01-01

    A PLant-ATmosphere INteraction model (PLATIN) was developed for estimating air pollutant absorbed doses under ambient conditions. PLATIN is based on the canopy energy balance combined with a gas transport submodel. The model has three major resistance components: (1) a turbulent atmospheric resistance Rah(zm) that describes the atmospheric transport properties between a measurement height above the canopy and the conceptual height z=d+z0m which represents the sink for momentum according to the big-leaf concept; (2) a quasilaminar layer resistance R(b,A) that quantifies the way in which the transfer of sensible heat and matter (e.g. latent heat, ozone) differs from momentum transfer; (3) a canopy or surface resistance R(c,A) that describes the influences of the plant/soil system on the exchange processes. Soil water content is simulated by a Force-Restore model. By a simple interception submodel precipitation and dew are partitioned into intercepted water and water reaching the soil surface. PLATIN can be run in a prognostic or a diagnostic mode. It is also intended for on-line use in air quality monitoring networks.

  15. Response functions for computing absorbed dose to skeletal tissues from photon irradiation—an update

    NASA Astrophysics Data System (ADS)

    Johnson, Perry B.; Bahadori, Amir A.; Eckerman, Keith F.; Lee, Choonsik; Bolch, Wesley E.

    2011-04-01

    A comprehensive set of photon fluence-to-dose response functions (DRFs) is presented for two radiosensitive skeletal tissues—active and total shallow marrow—within 15 and 32 bone sites, respectively, of the ICRP reference adult male. The functions were developed using fractional skeletal masses and associated electron-absorbed fractions as reported for the UF hybrid adult male phantom, which in turn is based upon micro-CT images of trabecular spongiosa taken from a 40 year male cadaver. The new DRFs expand upon both the original set of seven functions produced in 1985, and a 2007 update calculated under the assumption of secondary electron escape from spongiosa. In this study, it is assumed that photon irradiation of the skeleton will yield charged particle equilibrium across all spongiosa regions at energies exceeding 200 keV. Kerma coefficients for active marrow, inactive marrow, trabecular bone and spongiosa at higher energies are calculated using the DRF algorithm setting the electron-absorbed fraction for self-irradiation to unity. By comparing kerma coefficients and DRF functions, dose enhancement factors and mass energy-absorption coefficient (MEAC) ratios for active marrow to spongiosa were derived. These MEAC ratios compared well with those provided by the NIST Physical Reference Data Library (mean difference of 0.8%), and the dose enhancement factors for active marrow compared favorably with values calculated in the well-known study published by King and Spiers (1985 Br. J. Radiol. 58 345-56) (mean absolute difference of 1.9 percentage points). Additionally, dose enhancement factors for active marrow were shown to correlate well with the shallow marrow volume fraction (R2 = 0.91). Dose enhancement factors for the total shallow marrow were also calculated for 32 bone sites representing the first such derivation for this target tissue.

  16. Absorbed doses and radiation damage during the 11 years of LEP operation

    NASA Astrophysics Data System (ADS)

    Schönbacher, H.; Tavlet, M.

    2004-03-01

    During the 11 years of operation of the large electron-positron collider (LEP), synchrotron radiation was emitted in the tunnel. This ionizing radiation induced degradation in organic insulators and structural materials, as well as in electronics. Annual dosimetric measurements have shown that the level of radiation increased with the ninth power of the beam energy. During the machine shutdowns and at the end of the operation, samples of rigid and flexible polymeric insulators (magnet-coil resins and cable insulations) were taken out and checked for their integrity. The test results are compared with the results obtained during the qualification of the materials, 12-15 years ago. At that time, lifetime predictions were made; they are now compared with the real time-aged materials.

  17. Estimated human absorbed dose of ¹⁷⁷Lu-BPAMD based on mice data: Comparison with ¹⁷⁷Lu-EDTMP.

    PubMed

    Yousefnia, Hassan; Zolghadri, Samaneh; Shanehsazzadeh, Saeed

    2015-10-01

    In this work, the absorbed dose of human organs for (177)Lu-BPAMD was evaluated based on biodistribution studies into the Syrian mice by RADAR method and was compared with (177)Lu-EDTMP as the only clinically used Lu-177 bone-seeking agent. The highest absorbed dose for both (177)Lu-BPAMD and (177)Lu-EDTMP is observed on the bone surface with 8.007 and 4.802 mSv/MBq. Generally, (177)Lu-BPAMD has considerable characteristics compared with (177)Lu-EDTMP and can be considered as a promising agent for the bone pain palliation therapy. PMID:26163291

  18. Tumoral fibrosis effect on the radiation absorbed dose of (177)Lu-Tyr(3)-octreotate and (177)Lu-Tyr(3)-octreotate conjugated to gold nanoparticles.

    PubMed

    Azorín-Vega, E P; Zambrano-Ramírez, O D; Rojas-Calderón, E L; Ocampo-García, B E; Ferro-Flores, G

    2015-06-01

    The aim of this work was to evaluate the tumoral fibrosis effect on the radiation absorbed dose of the radiopharmaceuticals (177)Lu-Tyr(3)-octreotate (monomeric) and (177)Lu-Tyr(3)-octreotate-gold nanoparticles (multimeric) using an experimental HeLa cells tumoral model and the Monte Carlo PENELOPE code. Experimental and computer micro-environment models with or without fibrosis were constructed. Results showed that fibrosis increases up to 33% the tumor radiation absorbed dose, although the major effect on the dose was produced by the type of radiopharmaceutical (112Gy-multimeric vs. 43Gy-monomeric).

  19. Tumoral fibrosis effect on the radiation absorbed dose of (177)Lu-Tyr(3)-octreotate and (177)Lu-Tyr(3)-octreotate conjugated to gold nanoparticles.

    PubMed

    Azorín-Vega, E P; Zambrano-Ramírez, O D; Rojas-Calderón, E L; Ocampo-García, B E; Ferro-Flores, G

    2015-06-01

    The aim of this work was to evaluate the tumoral fibrosis effect on the radiation absorbed dose of the radiopharmaceuticals (177)Lu-Tyr(3)-octreotate (monomeric) and (177)Lu-Tyr(3)-octreotate-gold nanoparticles (multimeric) using an experimental HeLa cells tumoral model and the Monte Carlo PENELOPE code. Experimental and computer micro-environment models with or without fibrosis were constructed. Results showed that fibrosis increases up to 33% the tumor radiation absorbed dose, although the major effect on the dose was produced by the type of radiopharmaceutical (112Gy-multimeric vs. 43Gy-monomeric). PMID:25305748

  20. The effect of systematic set-up deviations on the absorbed dose distribution for left-sided breast cancer treated with respiratory gating

    NASA Astrophysics Data System (ADS)

    Edvardsson, A.; Ceberg, S.

    2013-06-01

    The aim of this study was 1) to investigate interfraction set-up uncertainties for patients treated with respiratory gating for left-sided breast cancer, 2) to investigate the effect of the inter-fraction set-up on the absorbed dose-distribution for the target and organs at risk (OARs) and 3) optimize the set-up correction strategy. By acquiring multiple set-up images the systematic set-up deviation was evaluated. The effect of the systematic set-up deviation on the absorbed dose distribution was evaluated by 1) simulation in the treatment planning system and 2) measurements with a biplanar diode array. The set-up deviations could be decreased using a no action level correction strategy. Not using the clinically implemented adaptive maximum likelihood factor for the gating patients resulted in better set-up. When the uncorrected set-up deviations were simulated the average mean absorbed dose was increased from 1.38 to 2.21 Gy for the heart, 4.17 to 8.86 Gy to the left anterior descending coronary artery and 5.80 to 7.64 Gy to the left lung. Respiratory gating can induce systematic set-up deviations which would result in increased mean absorbed dose to the OARs if not corrected for and should therefore be corrected for by an appropriate correction strategy.

  1. Comparison of Accuracy in Calculation of Absorbed Dose to Patients Following Bone Scan with 99mTc-Marked Diphosphonates by Two Different Background Correction Methods

    PubMed Central

    Shahbazi-Gahrouei, Daryoush; Damoori, Mehri; Tavakoli, Mohammad Bagher; Moslehi, Masoud

    2016-01-01

    To improve the accuracy of the activity quantification and the image quality in scintigraphy, scatter correction is a vital procedure. The aim of this study is to compare the accuracy in calculation of absorbed dose to patients following bone scan with 99mTc-marked diphosphonates (99mTc-MDP) by two different methods of background correction in conjugate view method. This study involved 22 patients referring to the Nuclear Medicine Center of Shahid Chamran Hospital, Isfahan, Iran. After the injection of 99mTc-MDP, whole-body images from patients were acquired at 10, 60, 90, and 180 min. Organ activities were calculated using the conjugate view method by Buijs and conventional background correction. Finally, the absorbed dose was calculated using the Medical Internal Radiation Dosimetry (MIRD) technique. The results of this study showed that the absorbed dose per unit of injected activity (rad/mCi) ± standard deviation for pelvis bone, bladder, and kidneys by Buijs method was 0.19 ± 0.05, 0.08 ± 0.01, and 0.03 ± 0.01 and by conventional method was 0.13 ± 0.04, 0.08 ± 0.01, and 0.024 ± 0.01, respectively. This showed that Buijs background correction method had a high accuracy compared to conventional method for the estimated absorbed dose of bone and kidneys whereas, for the bladder, its accuracy was low. PMID:27014610

  2. Absorbed dose estimates for positron emission tomography (PET): C/sup 15/O, /sup 11/CO, and CO/sup 15/O

    SciTech Connect

    Kearfott, K.J.

    1982-11-01

    Regional cerebral blood volume and blood flow may be determined using PET and C/sup 15/O, /sup 11/CO, and CO/sup 15/O. Detailed estimates of radiation absorbed dose for 22 organs and the whole body are reported and compared for these gases administered by continuous or bolus inhalation and by infusion techniques.

  3. Evaluation of absorbed dose in irradiated sugar-containing plant material (peony roots) by an ESR method

    NASA Astrophysics Data System (ADS)

    Yamaoki, Rumi; Kimura, Shojiro; Ohta, Masatoshi

    2015-12-01

    The relationship between electron spin resonance (ESR) signal intensity of irradiated plant materials and sugar content was investigated by spectral analysis using peony roots. A weak background signal near g=2.005 was observed in the roots. After a 10 kGy irradiation, the ESR line broadened and the intensity increased, and the spectral characteristics were similar to a typical spectrum of irradiated food containing crystalline sugars. The free radical concentration was nearly stable 30 days after irradiation. The spectrum of peony root 30 days after irradiation was simulated using the summation of the intensities of six assumed components: radical signals derived from (a) sucrose, (b) glucose, (c) fructose, (d) cellulose, (e) the background signal near g=2.005 and (f) unidentified component. The simulated spectra using the six components were in agreement with the observed sample spectra. The intensity of sucrose radical signal in irradiated samples increased proportionally up to 20 kGy. In addition, the intensity of sucrose radical signals was strongly correlated with the sucrose contents of the samples. The results showed that the radiation sensitivity of sucrose in peony roots was influenced little by other plant constituents. There was also a good correlation between the total area of the spectra and the sucrose content, because the sucrose content was higher than that of other sugars in the samples. In peony roots, estimation of the absorbed dose from the ESR signal intensity may be possible by a calibration method based on the sucrose content.

  4. Absorbed dose to man from the Se-75 labeled conjugated bile salt SeHCAT: concise communication

    SciTech Connect

    Soundy, R.G.; Simpson, J.D.; Ross, H.M.; Merrick, M.V.

    1982-02-01

    The absorbed radiation dose that would result from the oral or intravenous administration of SeHCAT (23-(75Se)selena-25-homotaurocholate) has been calculated using the MIRD tables and formulas and data from measurements of whole-body distribution and from long-term whole-body counting in rats, mice, and man. When SeHCAT is administered to normal subjects, the gallbladder is the critical organ, receiving 12 mrad (oral dose) or 22 mrad (i.v.) per microcurie. The whole-body dose is 1 mrad/microCi, whatever the route of administration. In severe hepatic failure the liver might receive 200 mrad/microCi. The activity likely to be used in routine clinical practice is 10 microCi. Where a whole-body counter is used, an activity of 1 microCi has proved adequate. Even at an administered activity of 25 microCi, the absorbed dose is small compared with established techniques of investigating the gastrointestinal tract.

  5. Absorbed dose to man from the Se-75 labeled conjugated bile salt SeHCAT: concise communication

    SciTech Connect

    Soundy, R.G.; Simpson, J.D.; Ross, H.M.; Merrick, M.V.

    1982-02-01

    The absorbed radiation dose that would result from the oral or intravenous administration of SeHCAT (23-(/sup 75/Se)selena-25-homotaurocholate) has been calculated using the MIRD tables and formulas and data from measurements of whole-body distribution and from long-term whole-body counting in rats, mice, and man. When SeHCAT is administered to normal subjects, the gallbladder is the critical organ, receiving 12 mrad (oral dose) or 22 mrad (i.v.) per microcurie. The whole-body dose is 1 mrad/..mu..Ci, whatever the route of administration. In severe hepatic failure the liver might receive 200 mrad/..mu..Ci. The activity likely to be used in routine clinical practice is 10 ..mu..Ci. Where a whole-body counter is used, an activity of 1 ..mu..Ci has proved adequate. Even at an administered activity of 25 ..mu..Ci, the absorbed dose is small compared with established techniques of investigating the gastrointestinal tract.

  6. Determination of absorbed dose of ozone (O3) in animals and humans using stable-isotope (oxygen-18) tracing

    SciTech Connect

    Hatch, G.E.; Aissa, M.

    1987-05-01

    A method for the determination of absorbed dose of ozone (O3) in animals and humans using oxygen-18 YO as a physiological tracer is presented. The experimental aspects of the method are based on the instantaneous pyrolysis of tissue samples and subsequent conversion of the sample oxygen to carbon monoxide then to carbon dioxide whose isotopic composition is determined by isotope-ratio mass spectrometry. A mathematical procedure is then used to correct the isotopic data for interferences from the blank and memory effects and from the iodine pentoxide oxidation of CO to CO2. Laboratory animals were exposed to YO3 (1 ppm, 1 hr) then tissues were dried and processed for YO measurement. Enrichments in YO over natural abundance YO was observed in lung homogenates, nasal cavities, trachea, and pulmonary lavage fluids but not in blood of mice, rats, and rabbits. Thus, the YO tracing method appears to be sensitive enough to detect the reaction products of YO in animals exposed to near environmental concentrations of this gas.

  7. SU-E-CAMPUS-I-06: Y90 PET/CT for the Instantaneous Determination of Both Target and Non-Target Absorbed Doses Following Hepatic Radioembolization

    SciTech Connect

    Pasciak, A; Kao, J

    2014-06-15

    Purpose The process of converting Yttrium-90 (Y90) PET/CT images into 3D absorbed dose maps will be explained. The simple methods presented will allow the medical physicst to analyze Y90 PET images following radioembolization and determine the absorbed dose to tumor, normal liver parenchyma and other areas of interest, without application of Monte-Carlo radiation transport or dose-point-kernel (DPK) convolution. Methods Absorbed dose can be computed from Y90 PET/CT images based on the premise that radioembolization is a permanent implant with a constant relative activity distribution after infusion. Many Y90 PET/CT publications have used DPK convolution to obtain 3D absorbed dose maps. However, this method requires specialized software limiting clinical utility. The Local Deposition method, an alternative to DPK convolution, can be used to obtain absorbed dose and requires no additional computer processing. Pixel values from regions of interest drawn on Y90 PET/CT images can be converted to absorbed dose (Gy) by multiplication with a scalar constant. Results There is evidence that suggests the Local Deposition method may actually be more accurate than DPK convolution and it has been successfully used in a recent Y90 PET/CT publication. We have analytically compared dose-volume-histograms (DVH) for phantom hot-spheres to determine the difference between the DPK and Local Deposition methods, as a function of PET scanner point-spread-function for Y90. We have found that for PET/CT systems with a FWHM greater than 3.0 mm when imaging Y90, the Local Deposition Method provides a more accurate representation of DVH, regardless of target size than DPK convolution. Conclusion Using the Local Deposition Method, post-radioembolization Y90 PET/CT images can be transformed into 3D absorbed dose maps of the liver. An interventional radiologist or a Medical Physicist can perform this transformation in a clinical setting, allowing for rapid prediction of treatment efficacy by

  8. Transcriptional Response in Mouse Thyroid Tissue after 211At Administration: Effects of Absorbed Dose, Initial Dose-Rate and Time after Administration

    PubMed Central

    Rudqvist, Nils; Spetz, Johan; Schüler, Emil; Parris, Toshima Z.; Langen, Britta; Helou, Khalil; Forssell-Aronsson, Eva

    2015-01-01

    Background 211At-labeled radiopharmaceuticals are potentially useful for tumor therapy. However, a limitation has been the preferential accumulation of released 211At in the thyroid gland, which is a critical organ for such therapy. The aim of this study was to determine the effect of absorbed dose, dose-rate, and time after 211At exposure on genome-wide transcriptional expression in mouse thyroid gland. Methods BALB/c mice were i.v. injected with 1.7, 7.5 or 100 kBq 211At. Animals injected with 1.7 kBq were killed after 1, 6, or 168 h with mean thyroid absorbed doses of 0.023, 0.32, and 1.8 Gy, respectively. Animals injected with 7.5 and 100 kBq were killed after 6 and 1 h, respectively; mean thyroid absorbed dose was 1.4 Gy. Total RNA was extracted from pooled thyroids and the Illumina RNA microarray platform was used to determine mRNA levels. Differentially expressed transcripts and enriched GO terms were determined with adjusted p-value <0.01 and fold change >1.5, and p-value <0.05, respectively. Results In total, 1232 differentially expressed transcripts were detected after 211At administration, demonstrating a profound effect on gene regulation. The number of regulated transcripts increased with higher initial dose-rate/absorbed dose at 1 or 6 h. However, the number of regulated transcripts decreased with mean absorbed dose/time after 1.7 kBq 211At administration. Furthermore, similar regulation profiles were seen for groups administered 1.7 kBq. Interestingly, few previously proposed radiation responsive genes were detected in the present study. Regulation of immunological processes were prevalent at 1, 6, and 168 h after 1.7 kBq administration (0.023, 0.32, 1.8 Gy). PMID:26177204

  9. SU-F-18C-08: A Validation Study of a Commercially Available Software Package's Absorbed Dose Estimates in a Physical Phantom

    SciTech Connect

    Supanich, M; Siegelman, J

    2014-06-15

    Purpose: This study assesses the accuracy of the absorbed dose estimates from CT scans generated by Monte Carlo (MC) simulation using a commercially available radiation dose monitoring software program. Methods: Axial CT studies of an anthropomorphic abdomen phantom with dose bores at a central location and 4 peripheral locations were conducted using a fixed tube current at 120 kV. A 100 mm ion chamber and a 0.6 cc ion chamber calibrated at diagnostic energy levels were used to measure dose in the phantom at each of the 5 dose bore locations. Simulations using the software program's Monte Carlo engine were run using a mathematical model of the anthropomorphic phantom to determine conversion coefficients between the CTDIvol used for the study and the dose at the location of the dose bores. Simulations were conducted using both the software's generic CT beam model and a refined model generated using HVL and bow tie filter profile measurements made on the scanner used for the study. Results: Monte Carlo simulations completed using the generalized beam model differed from the measured conversion factors by an absolute value average of 13.0% and 13.8% for the 100 mm and 0.6 cc ion chamber studies, respectively. The MC simulations using the scanner specific beam model generated conversion coefficients that differed from the CTDIvol to measured dose conversion coefficients by an absolute value average of 7.3% and 7.8% for the 100 mm and 0.6 cc ion chamber cases, respectively. Conclusion: A scanner specific beam model used in MC simulations generates more accurate dose conversion coefficients in an anthropomorphic phantom than those generated with a generalized beam model. Agreement between measured conversion coefficients and simulated values were less than 20% for all positions using the universal beam model.

  10. Reconstruction of Absorbed Doses to Fibroglandular Tissue of the Breast of Women undergoing Mammography (1960 to the Present)

    PubMed Central

    Thierry-Chef, Isabelle; Simon, Steven L.; Weinstock, Robert M.; Kwon, Deukwoo; Linet, Martha S.

    2013-01-01

    The assessment of potential benefits versus harms from mammographic examinations as described in the controversial breast cancer screening recommendations of the U.S. Preventive Task Force included limited consideration of absorbed dose to the fibroglandular tissue of the breast (glandular tissue dose), the tissue at risk for breast cancer. Epidemiological studies on cancer risks associated with diagnostic radiological examinations often lack accurate information on glandular tissue dose, and there is a clear need for better estimates of these doses. Our objective was to develop a quantitative summary of glandular tissue doses from mammography by considering sources of variation over time in key parameters including imaging protocols, x-ray target materials, voltage, filtration, incident air kerma, compressed breast thickness, and breast composition. We estimated the minimum, maximum, and mean values for glandular tissue dose for populations of exposed women within 5-year periods from 1960 to the present, with the minimum to maximum range likely including 90% to 95% of the entirety of the dose range from mammography in North America and Europe. Glandular tissue dose from a single view in mammography is presently about 2 mGy, about one-sixth the dose in the 1960s. The ratio of our estimates of maximum to minimum glandular tissue doses for average-size breasts was about 100 in the 1960s compared to a ratio of about 5 in recent years. Findings from our analysis provide quantitative information on glandular tissue doses from mammographic examinations which can be used in epidemiologic studies of breast cancer. PMID:21988547

  11. Monte Carlo calculations and measurements of absorbed dose per monitor unit for the treatment of uveal melanoma with proton therapy

    PubMed Central

    Koch, Nicholas; Newhauser, Wayne D; Titt, Uwe; Gombos, Dan; Coombes, Kevin; Starkschall, George

    2014-01-01

    The treatment of uveal melanoma with proton radiotherapy has provided excellent clinical outcomes. However, contemporary treatment planning systems use simplistic dose algorithms that limit the accuracy of relative dose distributions. Further, absolute predictions of absorbed dose per monitor unit are not yet available in these systems. The purpose of this study was to determine if Monte Carlo methods could predict dose per monitor unit (D/MU) value at the center of a proton spread-out Bragg peak (SOBP) to within 1% on measured values for a variety of treatment fields relevant to ocular proton therapy. The MCNPX Monte Carlo transport code, in combination with realistic models for the ocular beam delivery apparatus and a water phantom, was used to calculate dose distributions and D/MU values, which were verified by the measurements. Measured proton beam data included central-axis depth dose profiles, relative cross-field profiles and absolute D/MU measurements under several combinations of beam penetration ranges and range-modulation widths. The Monte Carlo method predicted D/MU values that agreed with measurement to within 1% and dose profiles that agreed with measurement to within 3% of peak dose or within 0.5 mm distance-to-agreement. Lastly, a demonstration of the clinical utility of this technique included calculations of dose distributions and D/MU values in a realistic model of the human eye. It is possible to predict D/MU values accurately for clinical relevant range-modulated proton beams for ocular therapy using the Monte Carlo method. It is thus feasible to use the Monte Carlo method as a routine absolute dose algorithm for ocular proton therapy. PMID:18367789

  12. WE-A-17A-01: Absorbed Dose Rate-To-Water at the Surface of a Beta-Emitting Planar Ophthalmic Applicator with a Planar, Windowless Extrapolation Chamber

    SciTech Connect

    Riley, A; Soares, C; Micka, J; Culberson, W; DeWerd, L

    2014-06-15

    Purpose: Currently there is no primary calibration standard for determining the absorbed dose rate-to-water at the surface of β-emitting concave ophthalmic applicators and plaques. Machining tolerances involved in the design of concave window extrapolation chambers are a limiting factor for development of such a standard. Use of a windowless extrapolation chamber avoids these window-machining tolerance issues. As a windowless extrapolation chamber has never been attempted, this work focuses on proof of principle measurements with a planar, windowless extrapolation chamber to verify the accuracy in comparison to initial calibration, which could be extended to the design of a hemispherical, windowless extrapolation chamber. Methods: The window of an extrapolation chamber defines the electrical field, aids in aligning the source parallel to the collector-guard assembly, and decreases the backscatter due to attenuation of lower electron energy. To create a uniform and parallel electric field in this research, the source was made common to the collector-guard assembly. A precise positioning protocol was designed to enhance the parallelism of the source and collector-guard assembly. Additionally, MCNP5 was used to determine a backscatter correction factor to apply to the calibration. With these issues addressed, the absorbed dose rate-to-water of a Tracerlab 90Sr planar ophthalmic applicator was determined using National Institute of Standards and Technology's (NIST) calibration formalism, and the results of five trials with this source were compared to measurements at NIST with a traditional extrapolation chamber. Results: The absorbed dose rate-to-water of the planar applicator was determined to be 0.473 Gy/s ±0.6%. Comparing these results to NIST's determination of 0.474 Gy/s yields a −0.6% difference. Conclusion: The feasibility of a planar, windowless extrapolation chamber has been demonstrated. A similar principle will be applied to developing a primary

  13. A 3D Monte Carlo Method for Estimation of Patient-specific Internal Organs Absorbed Dose for (99m)Tc-hynic-Tyr(3)-octreotide Imaging.

    PubMed

    Momennezhad, Mehdi; Nasseri, Shahrokh; Zakavi, Seyed Rasoul; Parach, Ali Asghar; Ghorbani, Mahdi; Asl, Ruhollah Ghahraman

    2016-01-01

    Single-photon emission computed tomography (SPECT)-based tracers are easily available and more widely used than positron emission tomography (PET)-based tracers, and SPECT imaging still remains the most prevalent nuclear medicine imaging modality worldwide. The aim of this study is to implement an image-based Monte Carlo method for patient-specific three-dimensional (3D) absorbed dose calculation in patients after injection of (99m)Tc-hydrazinonicotinamide (hynic)-Tyr(3)-octreotide as a SPECT radiotracer. (99m)Tc patient-specific S values and the absorbed doses were calculated with GATE code for each source-target organ pair in four patients who were imaged for suspected neuroendocrine tumors. Each patient underwent multiple whole-body planar scans as well as SPECT imaging over a period of 1-24 h after intravenous injection of (99m)hynic-Tyr(3)-octreotide. The patient-specific S values calculated by GATE Monte Carlo code and the corresponding S values obtained by MIRDOSE program differed within 4.3% on an average for self-irradiation, and differed within 69.6% on an average for cross-irradiation. However, the agreement between total organ doses calculated by GATE code and MIRDOSE program for all patients was reasonably well (percentage difference was about 4.6% on an average). Normal and tumor absorbed doses calculated with GATE were slightly higher than those calculated with MIRDOSE program. The average ratio of GATE absorbed doses to MIRDOSE was 1.07 ± 0.11 (ranging from 0.94 to 1.36). According to the results, it is proposed that when cross-organ irradiation is dominant, a comprehensive approach such as GATE Monte Carlo dosimetry be used since it provides more reliable dosimetric results.

  14. Relative Importance of Hip and Sacral Pain Among Long-Term Gynecological Cancer Survivors Treated With Pelvic Radiotherapy and Their Relationships to Mean Absorbed Doses

    SciTech Connect

    Waldenstroem, Ann-Charlotte; Olsson, Caroline; Wilderaeng, Ulrica; Dunberger, Gail; Lind, Helena; Alevronta, Eleftheria; Al-Abany, Massoud; Tucker, Susan; Avall-Lundqvist, Elisabeth; Johansson, Karl-Axel; Steineck, Gunnar

    2012-10-01

    Purpose: To investigate the relative importance of patient-reported hip and sacral pain after pelvic radiotherapy (RT) for gynecological cancer and its relationship to the absorbed doses in these organs. Methods and Materials: We used data from a population-based study that included 650 long-term gynecological cancer survivors treated with pelvic RT in the Gothenburg and Stockholm areas in Sweden with a median follow-up of 6 years (range, 2-15) and 344 population controls. Symptoms were assessed through a study-specific postal questionnaire. We also analyzed the hip and sacral dose-volume histogram data for 358 of the survivors. Results: Of the survivors, one in three reported having or having had hip pain after completing RT. Daily pain when walking was four times as common among the survivors compared to controls. Symptoms increased in frequency with a mean absorbed dose >37.5 Gy. Also, two in five survivors reported pain in the sacrum. Sacral pain also affected their walking ability and tended to increase with a mean absorbed dose >42.5 Gy. Conclusions: Long-term survivors of gynecological cancer treated with pelvic RT experience hip and sacral pain when walking. The mean absorbed dose was significantly related to hip pain and was borderline significantly related to sacral pain. Keeping the total mean absorbed hip dose below 37.5 Gy during treatment might lower the occurrence of long-lasting pain. In relation to the controls, the survivors had a lower occurrence of pain and pain-related symptoms from the hips and sacrum compared with what has previously been reported for the pubic bone.

  15. A 3D Monte Carlo Method for Estimation of Patient-specific Internal Organs Absorbed Dose for (99m)Tc-hynic-Tyr(3)-octreotide Imaging.

    PubMed

    Momennezhad, Mehdi; Nasseri, Shahrokh; Zakavi, Seyed Rasoul; Parach, Ali Asghar; Ghorbani, Mahdi; Asl, Ruhollah Ghahraman

    2016-01-01

    Single-photon emission computed tomography (SPECT)-based tracers are easily available and more widely used than positron emission tomography (PET)-based tracers, and SPECT imaging still remains the most prevalent nuclear medicine imaging modality worldwide. The aim of this study is to implement an image-based Monte Carlo method for patient-specific three-dimensional (3D) absorbed dose calculation in patients after injection of (99m)Tc-hydrazinonicotinamide (hynic)-Tyr(3)-octreotide as a SPECT radiotracer. (99m)Tc patient-specific S values and the absorbed doses were calculated with GATE code for each source-target organ pair in four patients who were imaged for suspected neuroendocrine tumors. Each patient underwent multiple whole-body planar scans as well as SPECT imaging over a period of 1-24 h after intravenous injection of (99m)hynic-Tyr(3)-octreotide. The patient-specific S values calculated by GATE Monte Carlo code and the corresponding S values obtained by MIRDOSE program differed within 4.3% on an average for self-irradiation, and differed within 69.6% on an average for cross-irradiation. However, the agreement between total organ doses calculated by GATE code and MIRDOSE program for all patients was reasonably well (percentage difference was about 4.6% on an average). Normal and tumor absorbed doses calculated with GATE were slightly higher than those calculated with MIRDOSE program. The average ratio of GATE absorbed doses to MIRDOSE was 1.07 ± 0.11 (ranging from 0.94 to 1.36). According to the results, it is proposed that when cross-organ irradiation is dominant, a comprehensive approach such as GATE Monte Carlo dosimetry be used since it provides more reliable dosimetric results. PMID:27134562

  16. A 3D Monte Carlo Method for Estimation of Patient-specific Internal Organs Absorbed Dose for 99mTc-hynic-Tyr3-octreotide Imaging

    PubMed Central

    Momennezhad, Mehdi; Nasseri, Shahrokh; Zakavi, Seyed Rasoul; Parach, Ali Asghar; Ghorbani, Mahdi; Asl, Ruhollah Ghahraman

    2016-01-01

    Single-photon emission computed tomography (SPECT)-based tracers are easily available and more widely used than positron emission tomography (PET)-based tracers, and SPECT imaging still remains the most prevalent nuclear medicine imaging modality worldwide. The aim of this study is to implement an image-based Monte Carlo method for patient-specific three-dimensional (3D) absorbed dose calculation in patients after injection of 99mTc-hydrazinonicotinamide (hynic)-Tyr3-octreotide as a SPECT radiotracer. 99mTc patient-specific S values and the absorbed doses were calculated with GATE code for each source-target organ pair in four patients who were imaged for suspected neuroendocrine tumors. Each patient underwent multiple whole-body planar scans as well as SPECT imaging over a period of 1-24 h after intravenous injection of 99mhynic-Tyr3-octreotide. The patient-specific S values calculated by GATE Monte Carlo code and the corresponding S values obtained by MIRDOSE program differed within 4.3% on an average for self-irradiation, and differed within 69.6% on an average for cross-irradiation. However, the agreement between total organ doses calculated by GATE code and MIRDOSE program for all patients was reasonably well (percentage difference was about 4.6% on an average). Normal and tumor absorbed doses calculated with GATE were slightly higher than those calculated with MIRDOSE program. The average ratio of GATE absorbed doses to MIRDOSE was 1.07 ± 0.11 (ranging from 0.94 to 1.36). According to the results, it is proposed that when cross-organ irradiation is dominant, a comprehensive approach such as GATE Monte Carlo dosimetry be used since it provides more reliable dosimetric results. PMID:27134562

  17. Ion chamber absorbed dose calibration coefficients, N{sub D,w}, measured at ADCLs: Distribution analysis and stability

    SciTech Connect

    Muir, B. R.

    2015-04-15

    Purpose: To analyze absorbed dose calibration coefficients, N{sub D,w}, measured at accredited dosimetry calibration laboratories (ADCLs) for client ionization chambers to study (i) variability among N{sub D,w} coefficients for chambers of the same type calibrated at each ADCL to investigate ion chamber volume fluctuations and chamber manufacturing tolerances; (ii) equivalency of ion chamber calibration coefficients measured at different ADCLs by intercomparing N{sub D,w} coefficients for chambers of the same type; and (iii) the long-term stability of N{sub D,w} coefficients for different chamber types by investigating repeated chamber calibrations. Methods: Large samples of N{sub D,w} coefficients for several chamber types measured over the time period between 1998 and 2014 were obtained from the three ADCLs operating in the United States. These are analyzed using various graphical and numerical statistical tests for the four chamber types with the largest samples of calibration coefficients to investigate (i) and (ii) above. Ratios of calibration coefficients for the same chamber, typically obtained two years apart, are calculated to investigate (iii) above and chambers with standard deviations of old/new ratios less than 0.3% meet stability requirements for accurate reference dosimetry recommended in dosimetry protocols. Results: It is found that N{sub D,w} coefficients for a given chamber type compared among different ADCLs may arise from differing probability distributions potentially due to slight differences in calibration procedures and/or the transfer of the primary standard. However, average N{sub D,w} coefficients from different ADCLs for given chamber types are very close with percent differences generally less than 0.2% for Farmer-type chambers and are well within reported uncertainties. Conclusions: The close agreement among calibrations performed at different ADCLs reaffirms the Calibration Laboratory Accreditation Subcommittee process of ensuring

  18. KEY COMPARISON: Comparison of the standards for absorbed dose to water of the ENEA-INMRI (Italy) and the BIPM for 60Co γ rays

    NASA Astrophysics Data System (ADS)

    Kessler, C.; Allisy-Roberts, P. J.; Burns, D. T.; Guerra, A. S.; Laitano, R. F.; Pimpinella, M.

    2010-01-01

    A comparison of the standards for absorbed dose to water of the Istituto Nazionale di Metrologia delle Radiazioni Ionizzanti of the Ente per le Nuove Tecnologie, l'Energia e l'Ambiente, Italy (ENEA-INMRI), and of the Bureau International des Poids et Mesures (BIPM) has been made in 60Co gamma radiation under the auspices of the key comparison BIPM.RI(I)-K4. The comparison result, based on the calibration coefficients for three transfer standards and expressed as a ratio of the ENEA and the BIPM standards for absorbed dose to water, is 0.9999 (0.0044). The present 2007 result replaces the earlier ENEA value in this key comparison. The degrees of equivalence between the ENEA and the other participants in this comparison have been calculated and the results are given in the form of a matrix for the ten national metrology institutes (NMIs) that have published results in this ongoing comparison for absorbed dose to water. A graphical presentation is also given. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI Section I, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).

  19. Direct measurement of absorbed dose to water in HDR {sup 192}Ir brachytherapy: Water calorimetry, ionization chamber, Gafchromic film, and TG-43

    SciTech Connect

    Sarfehnia, Arman; Kawrakow, Iwan; Seuntjens, Jan

    2010-04-15

    Purpose: Gafchromic film and ionometric calibration procedures for HDR {sup 192}Ir brachytherapy sources in terms of dose rate to water are presented and the experimental results are compared to the TG-43 protocol as well as with the absolute dose measurement results from a water calorimetry-based primary standard. Methods: EBT-1 Gafchromic films, an A1SL Exradin miniature Shonka thimble type chamber, and an SI HDR 1000 Plus well-type chamber (Standard Imaging, Inc., Middleton, WI) with an ADCL traceable S{sub k} calibration coefficient (following the AAPM TG-43 protocol) were used. The Farmer chamber and Gafchromic film measurements were performed directly in water. All results were compared to direct and absolute absorbed dose to water measurements from a 4 deg. C stagnant water calorimeter. Results: Based on water calorimetry, the authors measured the dose rate to water to be 361{+-}7 {mu}Gy/(h U) at a 55 mm source-to-detector separation. The dose rate normalized to air-kerma strength for all the techniques agree with the water calorimetry results to within 0.83%. The overall 1-sigma uncertainty on water calorimetry, ionization chamber, Gafchromic film, and TG-43 dose rate measurement amounts to 1.90%, 1.44%, 1.78%, and 2.50%, respectively. Conclusions: This work allows us to build a more realistic uncertainty estimate for absorbed dose to water determination using the TG-43 protocol. Furthermore, it provides the framework necessary for a shift from indirect HDR {sup 192}Ir brachytherapy dosimetry to a more accurate, direct, and absolute measurement of absorbed dose to water.

  20. Role of shielding in modulating the effects of solar particle events: Monte Carlo calculation of absorbed dose and DNA complex lesions in different organs

    NASA Astrophysics Data System (ADS)

    Ballarini, F.; Biaggi, M.; De Biaggi, L.; Ferrari, A.; Ottolenghi, A.; Panzarasa, A.; Paretzke, H. G.; Pelliccioni, M.; Sala, P.; Scannicchio, D.; Zankl, M.

    2004-01-01

    Distributions of absorbed dose and DNA clustered damage yields in various organs and tissues following the October 1989 solar particle event (SPE) were calculated by coupling the FLUKA Monte Carlo transport code with two anthropomorphic phantoms (a mathematical model and a voxel model), with the main aim of quantifying the role of the shielding features in modulating organ doses. The phantoms, which were assumed to be in deep space, were inserted into a shielding box of variable thickness and material and were irradiated with the proton spectra of the October 1989 event. Average numbers of DNA lesions per cell in different organs were calculated by adopting a technique already tested in previous works, consisting of integrating into "condensed-history" Monte Carlo transport codes - such as FLUKA - yields of radiobiological damage, either calculated with "event-by-event" track structure simulations, or taken from experimental works available in the literature. More specifically, the yields of "Complex Lesions" (or "CL", defined and calculated as a clustered DNA damage in a previous work) per unit dose and DNA mass (CL Gy -1 Da -1) due to the various beam components, including those derived from nuclear interactions with the shielding and the human body, were integrated in FLUKA. This provided spatial distributions of CL/cell yields in different organs, as well as distributions of absorbed doses. The contributions of primary protons and secondary hadrons were calculated separately, and the simulations were repeated for values of Al shielding thickness ranging between 1 and 20 g/cm 2. Slight differences were found between the two phantom types. Skin and eye lenses were found to receive larger doses with respect to internal organs; however, shielding was more effective for skin and lenses. Secondary particles arising from nuclear interactions were found to have a minor role, although their relative contribution was found to be larger for the Complex Lesions than for

  1. Production and in vivo imaging of (203)Pb as a surrogate isotope for in vivo (212)Pb internal absorbed dose studies.

    PubMed

    Máthé, Domokos; Szigeti, Krisztián; Hegedűs, Nikolett; Horváth, Ildikó; Veres, Dániel S; Kovács, Béla; Szűcs, Zoltán

    2016-08-01

    (212)Pb is a clinically relevant therapeutic alpha emitter isotope. A surrogate, (203)Pb, if prepared with sufficiently high specific activity could be used to estimate (212)Pb in vivo absorbed doses. An improved production procedure of (203)Pb with a simple, new separation method and high specific radioactivity for imaging is reported. We determined the in-vivo biodistribution of (203)Pb in mice by SPECT/CT. This highlights application possibilities of (203)Pb for further in vivo and clinical uses (radiolabeled (212)Pb-peptide co-injection, dosimetry calculation).

  2. Estimation of absorbed dose to the kidneys in patients after treatment with 177Lu-octreotate: comparison between methods based on planar scintigraphy

    PubMed Central

    2012-01-01

    Background Lu-[DOTA0, Tyr3]-octreotate (177Lu-octreotate) is used to treat neuroendocrine tumors with high somatostatin-receptor expression. 177Lu-octreotate is mainly excreted via the kidneys, but to some extent, accumulates in the kidney cortex due to, e.g., tubular reabsorption. Renal toxicity is one of the main limiting factors in 177Lu-octreotate treatment. Further knowledge of the biodistribution and dosimetry of 177Lu-octreotate in individual patients is needed. The aim of this study was to estimate the absorbed dose to the kidneys and compare the results obtained with planar imaging and different dosimetric methods: (1) conjugate-view (CV) method using patient-specific kidney sizes, (2) PA method, based on posterior images only, (3) CV method with reduced number of time points (CVreduced data), and (4) CV method using standard kidney sizes (CVstandard size). Methods Totally, 33 patients each received 3.4 to 8.2 GBq of 177Lu-octreotate up to five times, with infusion of lysine and arginine to block the renal uptake. Whole-body planar gamma camera images were acquired on days 0, 1, 2, and 7. The 177Lu concentration in the kidneys was determined by the CV method, and the absorbed dose was estimated with patient-specific organ sizes. Comparison to the CV method was made using posterior images only, together with the influence of the number of time points and with standard organ sizes. Results Large interindividual variations were found in the time-activity curve pattern and in the absorbed dose to the kidneys using the CV method: 0.33 to 2.4 Gy/GBq (mean =  0.80 Gy/GBq, SD = 0.30). In the individual patient, the mean deviation of all subsequent kidney doses compared to that of the first administration was 1% (SD = 19%) and 5% (SD = 23%) for the right and left kidneys, respectively. Excluding data for day 7 resulted in large variations in the absorbed dose. Conclusion Large interindividual variations in kidney dose were found, demonstrating the

  3. Density dependence of nuclear symmetry energy

    NASA Astrophysics Data System (ADS)

    Behera, B.; Routray, T. R.; Tripathy, S. K.

    2016-10-01

    High density behavior of nuclear symmetry energy is studied on the basis of the stiffest density dependence of asymmetric contribution to energy per nucleon in charge neutral n + p + e + μ matter under beta equilibrium. The density dependence of nuclear symmetry energy obtained in this way is neither very stiff nor soft at high densities and is found to be in conformity with recent observations of neutron stars.

  4. Neutron relative biological effectiveness for solid cancer incidence in the Japanese A-bomb survivors: an analysis considering the degree of independent effects from γ-ray and neutron absorbed doses with hierarchical partitioning.

    PubMed

    Walsh, Linda

    2013-03-01

    It has generally been assumed that the neutron and γ-ray absorbed doses in the data from the life span study (LSS) of the Japanese A-bomb survivors are too highly correlated for an independent separation of the all solid cancer risks due to neutrons and due to γ-rays. However, with the release of the most recent data for all solid cancer incidence and the increased statistical power over previous datasets, it is instructive to consider alternatives to the usual approaches. Simple excess relative risk (ERR) models for radiation-induced solid cancer incidence fitted to the LSS epidemiological data have been applied with neutron and γ-ray absorbed doses as separate explanatory covariables. A simple evaluation of the degree of independent effects from γ-ray and neutron absorbed doses on the all solid cancer risk with the hierarchical partitioning (HP) technique is presented here. The degree of multi-collinearity between the γ-ray and neutron absorbed doses has also been considered. The results show that, whereas the partial correlation between the neutron and γ-ray colon absorbed doses may be considered to be high at 0.74, this value is just below the level beyond which remedial action, such as adding the doses together, is usually recommended. The resulting variance inflation factor is 2.2. Applying HP indicates that just under half of the drop in deviance resulting from adding the γ-ray and neutron absorbed doses to the baseline risk model comes from the joint effects of the neutrons and γ-rays-leaving a substantial proportion of this deviance drop accounted for by individual effects of the neutrons and γ-rays. The average ERR/Gy γ-ray absorbed dose and the ERR/Gy neutron absorbed dose that have been obtained here directly for the first time, agree well with previous indirect estimates. The average relative biological effectiveness (RBE) of neutrons relative to γ-rays, calculated directly from fit parameters to the all solid cancer ERR model with both

  5. X-ray energy optimisation in computed microtomography.

    PubMed

    Spanne, P

    1989-06-01

    Expressions describing the absorbed dose and the number of incident photons necessary for the detection of a contrasting detail in x-ray transmission CT imaging of a circular phantom are derived as functions of the linear attenuation coefficients of the materials comprising the object and the detail. A shell of a different material can be included to allow simulation of CT imaging of the skulls of small laboratory animals. The equations are used to estimate the optimum photon energy in x-ray transmission computed microtomography. The optimum energy depends on whether the number of incident photons or the absorbed dose at a point in the object is minimised. For a water object of 300 mm diameter the two optimisation criteria yield optimum photon energies differing by an order of magnitude.

  6. Calculation of Absorbed Dose in Target Tissue and Equivalent Dose in Sensitive Tissues of Patients Treated by BNCT Using MCNP4C

    NASA Astrophysics Data System (ADS)

    Zamani, M.; Kasesaz, Y.; Khalafi, H.; Pooya, S. M. Hosseini

    Boron Neutron Capture Therapy (BNCT) is used for treatment of many diseases, including brain tumors, in many medical centers. In this method, a target area (e.g., head of patient) is irradiated by some optimized and suitable neutron fields such as research nuclear reactors. Aiming at protection of healthy tissues which are located in the vicinity of irradiated tissue, and based on the ALARA principle, it is required to prevent unnecessary exposure of these vital organs. In this study, by using numerical simulation method (MCNP4C Code), the absorbed dose in target tissue and the equiavalent dose in different sensitive tissues of a patiant treated by BNCT, are calculated. For this purpose, we have used the parameters of MIRD Standard Phantom. Equiavelent dose in 11 sensitive organs, located in the vicinity of target, and total equivalent dose in whole body, have been calculated. The results show that the absorbed dose in tumor and normal tissue of brain equal to 30.35 Gy and 0.19 Gy, respectively. Also, total equivalent dose in 11 sensitive organs, other than tumor and normal tissue of brain, is equal to 14 mGy. The maximum equivalent doses in organs, other than brain and tumor, appear to the tissues of lungs and thyroid and are equal to 7.35 mSv and 3.00 mSv, respectively.

  7. Comparison of the calculated absorbed dose using the Cadplan™ treatment planning software and Tld-100 measurements in an Alderson-Rando phantom for a bronchogenic treatment

    SciTech Connect

    Gutiérrez Castillo, J. G.; Álvarez Romero, J. T. E-mail: fisarmandotorres@gmail.com Calderón, A. Torres E-mail: fisarmandotorres@gmail.com M, V. Tovar E-mail: fisarmandotorres@gmail.com

    2014-11-07

    To verify the accuracy of the absorbed doses D calculated by a TPS Cadplan for a bronchogenic treatment (in an Alderson-Rando phantom) are chosen ten points with the following D's and localizations. Point 1, posterior position on the left edge with 136.4 Gy. Points: 2, 3 and 4 in the left lung with 104.9, 104.3 and 105.8 Gy, respectively; points 5 and 6 at the mediastinum with 192.4 and 173.5 Gy; points 7, 8 and 9 in the right lung with 105.8, 104.2 and 104.7 Gy, and 10 at posterior position on right edge with 143.7 Gy. IAEA type capsules with TLD 100 powder are placed, planned and irradiated. The evaluation of the absorbed dose is carried out a curve of calibration for the LiF response (nC) {sup vs} {sup DW}, to several cavity theories. The traceability for the DW is obtained with a secondary standard calibrated at the NRC (Canada). The dosimetric properties for the materials considered are determined from the Hounsfield numbers reported by the TPS. The stopping power ratios are calculated for nominal spectrum to 6 MV photons. The percent variations among the planned and determined D in all the cases they are < ± 3%.

  8. Key comparison BIPM.RI(I)-K4 of the absorbed dose to water standards of the PTB, Germany and the BIPM in 60Co gamma radiation

    NASA Astrophysics Data System (ADS)

    Kessler, C.; Burns, D. T.; Kapsch, R.-P.; Krauss, A.

    2016-01-01

    An indirect comparison has been made of the standards for absorbed dose to water in 60Co radiation of the Physikalisch-Technische Bundesanstalt, (PTB), Germany and of the Bureau International des Poids et Mesures (BIPM). The measurements at the BIPM were carried out in October 2015. The comparison result, based on the calibration coefficients for two transfer standards and evaluated as a ratio of the PTB and the BIPM standards for absorbed dose to water, is 0.9977 with a combined standard uncertainty of 3.8 × 10-3. The results are analysed and presented in terms of degrees of equivalence for entry in the BIPM key comparison database. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  9. Comparison of the calculated absorbed dose using the Cadplan™ treatment planning software and Tld-100 measurements in an Alderson-Rando phantom for a bronchogenic treatment

    NASA Astrophysics Data System (ADS)

    Gutiérrez Castillo, J. G.; Álvarez Romero, J. T.; Torres Calderón, A.; Tovar, M. V.

    2014-11-01

    To verify the accuracy of the absorbed doses D calculated by a TPS Cadplan for a bronchogenic treatment (in an Alderson-Rando phantom) are chosen ten points with the following D's and localizations. Point 1, posterior position on the left edge with 136.4 Gy. Points: 2, 3 and 4 in the left lung with 104.9, 104.3 and 105.8 Gy, respectively; points 5 and 6 at the mediastinum with 192.4 and 173.5 Gy; points 7, 8 and 9 in the right lung with 105.8, 104.2 and 104.7 Gy, and 10 at posterior position on right edge with 143.7 Gy. IAEA type capsules with TLD 100 powder are placed, planned and irradiated. The evaluation of the absorbed dose is carried out a curve of calibration for the LiF response (nC) vs DW, to several cavity theories. The traceability for the DW is obtained with a secondary standard calibrated at the NRC (Canada). The dosimetric properties for the materials considered are determined from the Hounsfield numbers reported by the TPS. The stopping power ratios are calculated for nominal spectrum to 6 MV photons. The percent variations among the planned and determined D in all the cases they are < ± 3%.

  10. Treatment of small-cell lung cancer xenografts with iodine-313-anti-neural cell adhesion molecule monoclonal antibody and evaluation of absorbed dose in tissue

    SciTech Connect

    Hosono, Makoto; Endo, Keigo; Hosono, Masako N.

    1994-02-01

    Human small-cell lung cancer (SCLC) is considered a feasible target for immunotherapy using a radiolabeled monoclonal antibody (Mab). A murine Mab, NE150 (IgG1), reacts with the neural cell adhesion molecule, which is identical to cluster 1 antigen of SCLC. To estimate their therapeutic effects, NE150 and an isotype-matched control Mab were labeled with {sup 131}I and administered intravenously as a single dose into athymic mice inoculated with a NCI-H69 SCLC xenograft. The absorbed dose in organs was also examined based upon a long-term biodistribution study of {sup 131}I-NE150. Tumors initial volume 563.4 {plus_minus} 223.5 mm{sup 3} treated with 11.1 MBq (300 {mu}Ci) of {sup 131}I-NE150 diminished and became invisible at days 30-33, demonstrating a 60-day mean growth delay to reach a tripled initial volume compared with sham-treated tumors. Cumulative absorbed doses were estimated to be 2310, 410, 500, 330, and 790 cGy for the tumor, liver, kidney, spleen and lung, respectively. Iodine-131-NE150 had potent therapeutic effects against SCLC transplants in athymic mice, however, careful assessment of the side effects, improvement of radioiodination and chimerization of the Mab might be necessary to achieve efficient targeting in clinical therapeutic applications. 25 refs., 2 figs., 3 tabs.

  11. Applying supersymmetry to energy dependent potentials

    SciTech Connect

    Yekken, R.; Lassaut, M.; Lombard, R.J.

    2013-11-15

    We investigate the supersymmetry properties of energy dependent potentials in the D=1 dimensional space. We show the main aspects of supersymmetry to be preserved, namely the factorization of the Hamiltonian, the connections between eigenvalues and wave functions of the partner Hamiltonians. Two methods are proposed. The first one requires the extension of the usual rules via the concept of local equivalent potential. In this case, the superpotential becomes depending on the state. The second method, applicable when the potential depends linearly on the energy, is similar to what has been already achieved by means of the Darboux transform. -- Highlights: •Supersymmetry extended to energy dependent potentials. •Generalization of the concept of superpotential. •An alternative method used for linear E-dependence leads to the same results as Darboux transform.

  12. Influence of phantom materials on the energy dependence of LiF:Mg,Ti thermoluminescent dosimeters exposed to 20-300 kV narrow x-ray spectra, 137Cs and 60Co photons.

    PubMed

    Massillon-J L, G; Cabrera-Santiago, A; Minniti, R; O'Brien, M; Soares, C G

    2014-08-01

    LiF:Mg,Ti, are widely used to estimate absorbed-dose received by patients during diagnostic or medical treatment. Conveniently, measurements are usually made in plastic phantoms. However, experimental conditions vary from one group to another and consequently, a lack of consensus data exists for the energy dependence of thermoluminescent (TL) response. This work investigated the energy dependence of TLD-100 TL-response and the effect of irradiating the dosimeters in different phantom materials for a broad range of energy photons in an attempt to understand the parameters that affect the discrepancies reported by various research groups. TLD-100s were exposed to 20-300 kV narrow x-ray spectra, (137)Cs and (60)Co photons. Measurements were performed in air, PMMA, wt1, polystyrene and TLDS as surrounding material. Total air-kerma values delivered were between 50 and 150 mGy for x-rays and 50 mGy for (137)Cs and (60)Co beams; each dosimeter was irradiated individually. Relative response, R, defined as the TL-response per air-kerma and relative efficiency, RE, described as the TL-response per absorbed-dose (obtained through Monte Carlo (MC) and analytically) were used to describe the TL-response. Both R and RE are normalized to the responses in a (60)Co beam. The results indicate that the use of different phantom materials affects the TL-response and this response varies with energy and material type. MC simulations reproduced qualitatively the experimental data: a) R increases, reaches a maximum at ~25 keV and decreases; b) RE decreases, down to a minimum at ~60 keV, increases to a maximum at ~150 keV and after decreases. Independent of the phantom materials, RE strongly depends on how the absorbed dose is evaluated and the discrepancies between RE evaluated analytically and by MC simulation are around 4% and 18%, dependent on the photon energy. The comparison between our results and that reported in the literature suggests that the discrepancy observed

  13. Renewable Energy Can Help Reduce Oil Dependency

    ScienceCinema

    Arvizu, Dan

    2016-07-12

    In a speech to the Economic Club of Kansas City on June 23, 2010, NREL Director Dan Arvizu takes a realistic look at how renewable energy can help reduce America's dependence on oil, pointing out that the country gets as much energy from renewable sources now as it does from offshore oil production. For a transcript, visit http://www.nrel.gov/director/pdfs/energy_overview_06_10.pdf

  14. Renewable Energy Can Help Reduce Oil Dependency

    SciTech Connect

    Arvizu, Dan

    2010-01-01

    In a speech to the Economic Club of Kansas City on June 23, 2010, NREL Director Dan Arvizu takes a realistic look at how renewable energy can help reduce America's dependence on oil, pointing out that the country gets as much energy from renewable sources now as it does from offshore oil production. For a transcript, visit http://www.nrel.gov/director/pdfs/energy_overview_06_10.pdf

  15. Role of shielding in modulating the effects of solar particle events: Monte Carlo calculation of absorbed dose and DNA complex lesions in different organs

    NASA Technical Reports Server (NTRS)

    Ballarini, F.; Biaggi, M.; De Biaggi, L.; Ferrari, A.; Ottolenghi, A.; Panzarasa, A.; Paretzke, H. G.; Pelliccioni, M.; Sala, P.; Scannicchio, D.; Zankl, M.; Townsend, L. W. (Principal Investigator)

    2004-01-01

    Distributions of absorbed dose and DNA clustered damage yields in various organs and tissues following the October 1989 solar particle event (SPE) were calculated by coupling the FLUKA Monte Carlo transport code with two anthropomorphic phantoms (a mathematical model and a voxel model), with the main aim of quantifying the role of the shielding features in modulating organ doses. The phantoms, which were assumed to be in deep space, were inserted into a shielding box of variable thickness and material and were irradiated with the proton spectra of the October 1989 event. Average numbers of DNA lesions per cell in different organs were calculated by adopting a technique already tested in previous works, consisting of integrating into "condensed-history" Monte Carlo transport codes--such as FLUKA--yields of radiobiological damage, either calculated with "event-by-event" track structure simulations, or taken from experimental works available in the literature. More specifically, the yields of "Complex Lesions" (or "CL", defined and calculated as a clustered DNA damage in a previous work) per unit dose and DNA mass (CL Gy-1 Da-1) due to the various beam components, including those derived from nuclear interactions with the shielding and the human body, were integrated in FLUKA. This provided spatial distributions of CL/cell yields in different organs, as well as distributions of absorbed doses. The contributions of primary protons and secondary hadrons were calculated separately, and the simulations were repeated for values of Al shielding thickness ranging between 1 and 20 g/cm2. Slight differences were found between the two phantom types. Skin and eye lenses were found to receive larger doses with respect to internal organs; however, shielding was more effective for skin and lenses. Secondary particles arising from nuclear interactions were found to have a minor role, although their relative contribution was found to be larger for the Complex Lesions than for the

  16. An ICRP-based Chinese adult male voxel model and its absorbed dose for idealized photon exposures--the skeleton.

    PubMed

    Liu, Liye; Zeng, Zhi; Li, Junli; Zhang, Binquan; Qiu, Rui; Ma, Jizeng

    2009-11-01

    A site-specific skeleton voxel model for a Chinese adult male was constructed in this paper upon a previous Chinese individual voxel model. The whole skeleton was divided into 19 site-specific bones and bone groups; the mass of various skeleton tissues at each bone site, e.g. red bone marrow, was specified according to Asian reference data and the distribution data from ICRP Publication 70. The resultant voxel model (called CAM) has a resolution of 1.741 mm x 1.741 mm in plane, and the total bone mass is 8397.8 g which is almost equal to the Asian reference value. Dose coefficients for the red bone marrow and bone surface in CAM were calculated, and then compared with those from Rex, CMP and ICRP 74. It shows that the dose to RBM in Rex is generally 12% lower than that to CAM in low-energy range (30-150 keV) for AP, LAT, ROT and ISO geometries. It is also found that the RBM dose from mathematical models, i.e. CMP and ICRP 74, is underestimated by -30% in AP geometry and overestimated by 30% in PA geometry for low-energy photons. Meanwhile, the bone surface dose in the low-energy range is overestimated by 150% and 75% in CMP and ICRP 74, respectively, if compared with that from CAM. PMID:19841519

  17. An ICRP-based Chinese adult male voxel model and its absorbed dose for idealized photon exposures—the skeleton

    NASA Astrophysics Data System (ADS)

    Liu, Liye; Zeng, Zhi; Li, Junli; Zhang, Binquan; Qiu, Rui; Ma, Jizeng

    2009-11-01

    A site-specific skeleton voxel model for a Chinese adult male was constructed in this paper upon a previous Chinese individual voxel model. The whole skeleton was divided into 19 site-specific bones and bone groups; the mass of various skeleton tissues at each bone site, e.g. red bone marrow, was specified according to Asian reference data and the distribution data from ICRP Publication 70. The resultant voxel model (called CAM) has a resolution of 1.741 mm × 1.741 mm in plane, and the total bone mass is 8397.8 g which is almost equal to the Asian reference value. Dose coefficients for the red bone marrow and bone surface in CAM were calculated, and then compared with those from Rex, CMP and ICRP 74. It shows that the dose to RBM in Rex is generally 12% lower than that to CAM in low-energy range (30-150 keV) for AP, LAT, ROT and ISO geometries. It is also found that the RBM dose from mathematical models, i.e. CMP and ICRP 74, is underestimated by -30% in AP geometry and overestimated by 30% in PA geometry for low-energy photons. Meanwhile, the bone surface dose in the low-energy range is overestimated by 150% and 75% in CMP and ICRP 74, respectively, if compared with that from CAM.

  18. Fluence-to-Absorbed Dose Conversion Coefficients for Use in Radiological Protection of Embryo and Foetus Against External Exposure to Muons from 20MeV to 50GeV

    SciTech Connect

    Chen Jing

    2008-08-07

    This study used the Monte-Carlo code MCNPX to determine mean absorbed doses to the embryo and foetus when the mother is exposed to external muon fields. Monoenergetic muons ranging from 20 MeV to 50 GeV were considered. The irradiation geometries include anteroposterior (AP), postero-anterior (PA), lateral (LAT), rotational (ROT), isotropic (ISO), and top-down (TOP). At each of these irradiation geometries, absorbed doses to the foetal body were calculated for the embryo of 8 weeks and the foetus of 3, 6 or 9 months, respectively. Muon fluence-to-absorbed-dose conversion coefficients were derived for the four prenatal ages. Since such conversion coefficients are yet unknown, the results presented here fill a data gap.

  19. [Comparison of the absorbed dose at calibration depth of photon beams using the Japan Society of Medical Physics 12 beam quality conversion factor in the presence or absence of a waterproofing sleeve].

    PubMed

    Kinoshita, Naoki; Takemura, Akihiro; Kita, Akinobu; Murai, Emi; Nishimoto, Yasuhiro; Toi, Akiko; Shimada, Masato; Sasamoto, Kouhei; Adachi, Toshiki

    2013-10-01

    In standard external beam radiotherapy dosimetry, which is based on absorbed dose by water, the absorbed dose at any calibration depth is calculated using the same beam quality conversion factor, regardless of the presence or absence of a waterproofing sleeve. In this study, we evaluated whether there were differences between absorbed doses at calibration depths calculated using a beam quality conversion factor including a wall correction factor that corresponds to a waterproofing sleeve thickness of 0.3 mm, and without a waterproofing sleeve. The Japan Society of Medical Physics (JSMP) has reported that the uncertainty of the results using a beam quality conversion factor that included a wall correction factor corresponding to a waterproofing sleeve thickness of 0.3 mm, regardless of the presence or absence of the sleeve, was 0.2%. This uncertainty proved to be in agreement with the reported range.

  20. Calculation of the absorbed dose for the overexposed patients at the JCO criticality accident in Tokai-mura.

    PubMed

    Ishigure, N; Endo, A; Yamaguchi, Y; Kawachi, K

    2001-09-01

    The doses for the overexposed patients were estimated by the measurement result of specific activity of 24Na in blood. The present method is almost based on documents of the International Atomic Energy Agency (IAEA) and the Oak Ridge National Laboratory. The neutron energy spectrum obtained using the ANISN code (Multigroup One-Dimensional Discrete Ordinates Transport Code System with Anisotropic Scattering) was assumed. The values in ICRP Publication 74 were applied for the doses in each organ per unit neutron fluence. Gamma-ray dose was indirectly estimated based on (a) the result of environmental monitoring around the accident site and (b) a graph in IAEA manual, which gives the kerma ratio of neutrons and gamma-rays as a function of the critical volume or the atomic ratio of hydrogen to 235U. The estimated neutron doses were 5.4 Gy for patient A. 2.9 Gy for patient B and 0.81 Gy for patient C. The estimated gamma-ray doses were 8.5 or 13 Gy for patient A, 4.5 or 6.9 Gy for patient B, and 1.3 or 2.0 Gy for patient C. PMID:11791747

  1. Energy dependent 4-dimensional multiple scattering distributions

    NASA Astrophysics Data System (ADS)

    Tschalär, C.

    1984-12-01

    A complete analytic solution in Fourier space is presented of the four dimensional small angle, multiple scattering distribution MSD in angle and space, produced by an energy dependent single scattering cross section from an initial pencil beam of heavy particles. Independently, simple integrals are derived for the central moments of the energy dependent MSD in the continuous-slowing-down approximation. The distributions of the projections t and x of the scattering angle and displacement into a plane through the axis of propagation are evaluated numerically for a truncated Rutherford scattering cross section using a fast Fourier transform. The resulting MSDs for a wide range of particles, initial and final momenta, and scattering materials are found to be approximately represented by one-dimensional set of standard distributions symmetrized by a linear transformation in t- x-space.

  2. High-Dose 131I-Tositumomab (Anti-CD20) Radioimmunotherapy for Non-Hodgkin's Lymphoma: Adjusting Radiation Absorbed Dose to Actual Organ Volumes

    SciTech Connect

    Rajendran, Joseph G.; Fisher, Darrell R.; Gopal, A K.; Durack, L. D.; Press, O. W.; Eary, Janet F.

    2004-06-01

    Radioimmunotherapy (RIT) using 131I-tositumomab has been used successfully to treat relapsed or refractory B-cell non-Hodgin's lymphoma (NHL). Our approach to treatment planning has been to determine limits on radiation absorbed close to critical nonhematopoietic organs. This study demonstrates the feasibility of using CT to adjust for actual organ volumes in calculating organ-specific absorbed dose estimates. Methods: Records of 84 patients who underwent biodistribution studies after a trace-labeled infusion of 131I-tositumomab for RIT (January 1990 and April 2003) were reviewed. Serial planar -camera images and whole-body Nal probe counts were obtained to estimate 131I-antibody source-organ residence times as recommended by the MIRD Committee. The source-organ residence times for standard man or woman were adjusted by the ratio of the MIRD phantom organ mass to the CT-derived organ mass. Results: The mean radiation absorbed doses (in mGy/MBq) for our data using the MIRD model were lungs= 1.67; liver= 1.03; kidneys= 1.08; spleen= 2.67; and whole body= 0.3; and for CT volume-adjusted organ volumes (in mGy/MBq) were lungs= 1.30; liver= 0.92; kidneys= 0.76; spleen= 1.40; and whole body= 0.22. We determined the following correlation coefficients between the 2 methods for the various organs; lungs, 0.49; (P= 0.0001); liver, 0.64 (P= 0.004); kidneys, 0.45 (P= 0.0001), for the residence times. For therapy, patients received mean 131I administered activities of 19.2 GBq (520 mCi) after adjustment for CT-derived organ mass compared with 16.0 GBq (433 mCi) that would otherwise have been given had therapy been based only using standard MIRD organ volumes--a statistically significant difference (P= 0.0001). Conclusion: We observed large variations in organ masses among our patients. Our treatments were planned to deliver the maximally tolerated radiation dose to the dose-limiting normal organ. This work provides a simplified method for calculating patient-specific radiation

  3. Role of cardiac ultrafast cameras with CZT solid-state detectors and software developments on radiation absorbed dose reduction to the patients.

    PubMed

    Gunalp, Bengul

    2015-07-01

    Myocardial perfusion imaging (MPI) is one the most contributing nuclear medicine technique to the annual population dose. The purpose of this study is to compare radiation-absorbed doses to the patients examined by conventional cardiac SPECT (CSPECT) camera and ultrafast cardiac (UFC) camera with cadmium-zinc-telluride (CZT) solid-state detectors. Total injected activity was reduced by 50 % when both stress and rest images were acquired and by 75 % when only stress images were taken with UFC camera. As a result of this, the mean total effective dose was found significantly lower with UFC camera (2.2 ± 1.2 mSv) than CSPECT (7.7 ± 3.8 mSv) (p < 0.001). Further dose reduction was obtained by reducing equivocal test results and unnecessary additional examinations with UFC camera. Using UFC camera, MPI can be conveniently used for the detection of coronary artery disease (CAD) much less increasing annual population radiation dose as it had been before. PMID:25848109

  4. SU-E-T-308: Systematic Characterization of the Energy Response of Different LiF TLD Crystals for Dosimetry Applications

    SciTech Connect

    Pena, E; Caprile, P; Sanchez-Nieto, B

    2014-06-01

    Purpose: The thermoluminiscense dosimeters (TLDs) are widely used in personal and clinical dosimetry due to its small size, good sensitivity and tissue equivalence, among other advantages. This study presents the characterization of Lithium Fluoride based TLDs, in terms of their absorbed dose response to successive irradiation cycles in a broad range of beam energies, measured under reference conditions. Methods: Four types of Harshaw TLD chips were used: TLD-100, TLD-600 TLD-700 and 100-H. They were irradiated with 10 photon beams of different energy spectrums, from 28 kVp to 18MV (in 30 consecutive cycles for 6 and 18 MV). Results: It was found that the response of the dosimetric system was stabilized (less than ±3%) after 10 cycles for TLD-600 and TLD-700. In the case of TLD-100 and TLD-100H this dependence was not observed. A decreased response to increasing beam energy in terms of absorbed dose to water was observed, as expected, except for TLD-100H which showed the opposite behavior. The less energy dependent detector was the TLD-100H exhibiting a maximum deviation of 12%. The highest variation observed was 33% for TLD-100. The study allowed the determination of calibration factors in absorbed dose for a wide range of energies and materials for different dosimetric applications, such as in-vivo dosimetry during imaging and radiotherapy. Conclusion: The study allowed the determination of calibration factors in absorbed dose for a wide range of energies and materials for different dosimetric applications, such as in-vivo dosimetry during imaging and radiotherapy.

  5. Energy-dependent cell cohesion in myxobacteria.

    PubMed

    Gilmore, D F; White, D

    1985-01-01

    Cohesion in the myxobacterium Stigmatella aurantiaca was characterized. Two classes of cohesion were revealed, termed class A and class B. Class A cohesion is a characteristic of vegetative cells grown in tryptone or casitone (Difco Laboratories, Detroit, Mich.), whereas class B cohesion requires the addition of calcium ion for induction. Class A cohesion occurs in the presence of any cation and is temperature independent. Class B cohesion requires the presence of a cation in the calcium group and is energy dependent. We conclude that S. aurantiaca responds to calcium ion by synthesizing the molecular components of a system of cell cohesion (class B) and that the functioning of this system requires the expenditure of metabolic energy.

  6. A water calorimeter for on-site absorbed dose to water calibrations in (60)Co and MV-photon beams including MRI incorporated treatment equipment.

    PubMed

    de Prez, Leon; de Pooter, Jacco; Jansen, Bartel; Aalbers, Tony

    2016-07-01

    In reference dosimetry the aim is to establish the absorbed dose to water, D w, under reference conditions. However, existing dosimetry protocols are not always applicable for rapidly emerging new treatment modalities. For primary standard dosimetry laboratories it is generally not feasible to acquire such modalities. Therefore it is strongly desired that D w measurements with primary standards can be performed on-site in clinical beams for the new treatment modalities in order to characterize and calibrate detectors. To serve this need, VSL has developed a new transportable water calorimeter serving as a primary D w standard for (60)Co and MV-photons including MRI incorporated treatment equipment. Special attention was paid to its operation in different beam geometries and beam modalities including the application in magnetic fields. The new calorimeter was validated in the VSL (60)Co beam and on-site in clinical MV-photon beams. Excellent agreement of 0.1% was achieved with previous (60)Co field calibrations, i.e. well within the uncertainty of the previous calorimeter, and with measurements performed in horizontal and vertical MV-photon beams. k Q factors, determined for two PTW 30013 ionization chambers, agreed very well with available literature data. The relative combined standard uncertainty (k  =  1) for D w measurements in (60)Co and MV-photons is 0.37%. Calibrations are carried out with a standard uncertainty of 0.42% and k Q -factors are determined with a relative standard uncertainty of 0.40%. PMID:27300589

  7. A water calorimeter for on-site absorbed dose to water calibrations in 60Co and MV-photon beams including MRI incorporated treatment equipment

    NASA Astrophysics Data System (ADS)

    de Prez, Leon; de Pooter, Jacco; Jansen, Bartel; Aalbers, Tony

    2016-07-01

    In reference dosimetry the aim is to establish the absorbed dose to water, D w, under reference conditions. However, existing dosimetry protocols are not always applicable for rapidly emerging new treatment modalities. For primary standard dosimetry laboratories it is generally not feasible to acquire such modalities. Therefore it is strongly desired that D w measurements with primary standards can be performed on-site in clinical beams for the new treatment modalities in order to characterize and calibrate detectors. To serve this need, VSL has developed a new transportable water calorimeter serving as a primary D w standard for 60Co and MV-photons including MRI incorporated treatment equipment. Special attention was paid to its operation in different beam geometries and beam modalities including the application in magnetic fields. The new calorimeter was validated in the VSL 60Co beam and on-site in clinical MV-photon beams. Excellent agreement of 0.1% was achieved with previous 60Co field calibrations, i.e. well within the uncertainty of the previous calorimeter, and with measurements performed in horizontal and vertical MV-photon beams. k Q factors, determined for two PTW 30013 ionization chambers, agreed very well with available literature data. The relative combined standard uncertainty (k  =  1) for D w measurements in 60Co and MV-photons is 0.37%. Calibrations are carried out with a standard uncertainty of 0.42% and k Q -factors are determined with a relative standard uncertainty of 0.40%.

  8. Dynamic evaluation of absorbed dose to the bladder wall with a balloon-bladder phantom during a study using [(18)F]fluorodeoxyglucose positron emission imaging.

    PubMed

    Wu, T H; Liu, R S; Dong, S L; Chung, Y W; Chou, K L; Lee, J S

    2002-08-01

    An accurate evaluation of the absorbed dose to the bladder wall from 2-[(18)F]fluoro-2-deoxy-d-glucose (FDG) is clinically important because the bladder is considered as a critical organ in most positron emission tomography (PET) studies that cumulate about 20% of the total activity injection during image procedures. In the MIRD calculation, no allowance is made for the inclusion of all the dynamic parameters that affect the actual dose to the bladder wall to be taken in the dose assessment. The goal of the study is to propose a dose evaluation model by using a dynamic bladder phantom and time-activity curves from the bladder PET imaging. The proposed model takes all dynamic parameters into account and provides a much more accurate dose estimation to the bladder. In this study, the lowest dose to the bladder wall was obtained at the conditions of having a larger initial volume for the bladder contents and a higher production rate for urine. It is then advised patients to drink a bulk amount of water before the FDG injection or after urine voiding to facilitate urine production and to enlarge the bladder surface area, which are the most crucial steps in reducing the dose to the bladder wall. In our study, the voiding schedule in dose calculation plays certain roles although it is much more critical in the conventional MIRD calculation. The model estimated that the lowest dose to the bladder would occur at an initial void about 40 min after the FDG injection and the urine voiding was as complete as possible. PMID:12124480

  9. EURAMET.RI(I)-S7 comparison of alanine dosimetry systems for absorbed dose to water measurements in gamma- and x-radiation at radiotherapy levels

    NASA Astrophysics Data System (ADS)

    Garcia, Tristan; Anton, Mathias; Sharpe, Peter

    2012-01-01

    The National Physical Laboratory (NPL), the Physikalisch-Technische Bundesanstalt (PTB) and the Laboratoire National Henri Becquerel (LNE-LNHB) are involved in the European project 'External Beam Cancer Therapy', a project of the European Metrology Research Programme. Within this project, the electron paramagnetic resonance (EPR)/alanine dosimetric method has been chosen for performing measurements in small fields such as those used in IMRT (intensity modulated radiation therapy). In this context, these three National Metrology Institutes (NMI) wished to compare the result of their alanine dosimetric systems (detector, modus operandi etc) at radiotherapy dose levels to check their consistency. This EURAMET.RI(I)-S7 comparison has been performed with the support of the Bureau International des Poids et Mesures (BIPM) which collected and distributed the results as a neutral organization, to ensure the comparison was 'blind'. Irradiations have been made under reference conditions by each laboratory in a 60Co beam and in an accelerator beam (10 MV or 12 MV) in a water phantom of 30 cm × 30 cm × 30 cm in a square field of 10 cm × 10 cm at the reference depth. Irradiations have been performed at known values of absorbed dose to water (Dw) within 10% of nominal doses of 5 Gy and 10 Gy, i.e. between 4.5 Gy and 5.5 Gy and between 9 Gy and 11 Gy, respectively. Each participant read out their dosimeters and assessed the doses using their own protocol (calibration curve, positioning device etc) as this comparison aims at comparing the complete dosimetric process. The results demonstrate the effectiveness of the EPR/alanine dosimetry systems operated by National Metrology Institutes as a method of assuring therapy level doses with the accuracy required. The maximum deviation in the ratio of measured to applied dose is less than 1%. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key

  10. Energy deposition at the bone-tissue interface from nuclear fragments produced by high-energy nucleons

    NASA Technical Reports Server (NTRS)

    Cucinotta, Francis A.; Hajnal, Ferenc; Wilson, John W.

    1990-01-01

    The transport of nuclear fragmentation recoils produced by high-energy nucleons in the region of the bone-tissue interface is considered. Results for the different flux and absorbed dose for recoils produced by 1 GeV protons are presented in a bidirectional transport model. The energy deposition in marrow cavities is seen to be enhanced by recoils produced in bone. Approximate analytic formulae for absorbed dose near the interface region are also presented for a simplified range-energy model.

  11. Constraints on cosmological birefringence energy dependence from CMB polarization data

    SciTech Connect

    Gubitosi, G.; Paci, F. E-mail: fpaci@sissa.it

    2013-02-01

    We study the possibility of constraining the energy dependence of cosmological birefringence by using CMB polarization data. We consider four possible behaviors, characteristic of different theoretical scenarios: energy-independent birefringence motivated by Chern-Simons interactions of the electromagnetic field, linear energy dependence motivated by a 'Weyl' interaction of the electromagnetic field, quadratic energy dependence, motivated by quantum gravity modifications of low-energy electrodynamics, and inverse quadratic dependence, motivated by Faraday rotation generated by primordial magnetic fields. We constrain the parameters associated to each kind of dependence and use our results to give constraints on the models mentioned. We forecast the sensitivity that Planck data will be able to achieve in this respect.

  12. Scale Dependence of Dark Energy Antigravity

    NASA Astrophysics Data System (ADS)

    Perivolaropoulos, L.

    2002-09-01

    We investigate the effects of negative pressure induced by dark energy (cosmological constant or quintessence) on the dynamics at various astrophysical scales. Negative pressure induces a repulsive term (antigravity) in Newton's law which dominates on large scales. Assuming a value of the cosmological constant consistent with the recent SnIa data we determine the critical scale $r_c$ beyond which antigravity dominates the dynamics ($r_c \\sim 1Mpc $) and discuss some of the dynamical effects implied. We show that dynamically induced mass estimates on the scale of the Local Group and beyond are significantly modified due to negative pressure. We also briefly discuss possible dynamical tests (eg effects on local Hubble flow) that can be applied on relatively small scales (a few $Mpc$) to determine the density and equation of state of dark energy.

  13. Density-dependent covariant energy density functionals

    SciTech Connect

    Lalazissis, G. A.

    2012-10-20

    Relativistic nuclear energy density functionals are applied to the description of a variety of nuclear structure phenomena at and away fromstability line. Isoscalar monopole, isovector dipole and isoscalar quadrupole giant resonances are calculated using fully self-consistent relativistic quasiparticle randomphase approximation, based on the relativistic Hartree-Bogoliubovmodel. The impact of pairing correlations on the fission barriers in heavy and superheavy nuclei is examined. The role of pion in constructing desnity functionals is also investigated.

  14. Evaluation of the mean energy deposit during the impact of charged particles on liquid water

    NASA Astrophysics Data System (ADS)

    Bernal, M. A.

    2012-04-01

    The DNA strand break yield due to the impact of ionizing particles on living beings is closely related to the number of inelastic events per unit absorbed dose produced by these particles. The higher this number, the higher the probability of causing DNA strand breaks per unit absorbed dose. In a previous work, it was found that the total number of events produced by primary particles and the secondary electrons is almost independent of the type and energy of the incident particle (or LET). This finding could be supported by a quasi-constant mean energy deposit by inelastic event (\\bar{\\varepsilon }). In this work, \\bar{\\varepsilon } was defined and determined for electrons and the non-negative charge states of hydrogen (H0, +) and helium (He0, +, 2 +) species impacting on liquid water. Ionization, excitation and charge transfer (up to two-electron transfers) processes have been included in present calculations. We found that, for liquid water, \\bar{\\varepsilon } is within 13.7 ± 4.1 eV, 14.2 ± 1.7 eV and 13.8 ± 1.4 eV for electrons, hydrogen and helium species, respectively, with impact energies changing over three orders of magnitude. Unlike the mean excitation energy, the mean energy deposit per inelastic event depends not only on the target molecule but also on the projectile features. However, this dependence is relatively weak. This fact supports the quasi-independent number of inelastic events per unit absorbed dose found previously when charged particles impact on matter.

  15. Data on biodistribution and radiation absorbed dose profile of a novel (64)Cu-labeled high affinity cell-specific peptide for positron emission tomography imaging of tumor vasculature.

    PubMed

    Merrill, Joseph R; Krajewski, Krzysztof; Yuan, Hong; Frank, Jonathan E; Lalush, David S; Patterson, Cam; Veleva, Anka N

    2016-06-01

    New peptide-based diagnostic and therapeutic approaches hold promise for highly selective targeting of cancer leading to more precise and effective diagnostic and therapeutic modalities. An important feature of these approaches is to reach the tumor tissue while limiting or minimizing the dose to normal organs. In this context, efforts to design and engineer materials with optimal in vivo targeting and clearance properties are important. This Data In Brief article reports on biodistribution and radiation absorbed dose profile of a novel high affinity radiopeptide specific for bone marrow-derived tumor vasculature. Background information on the design, preparation, and in vivo characterization of this peptide-based targeted radiodiagnostic is described in the article "Synthesis and comparative evaluation of novel 64Cu-labeled high affinity cell-specific peptides for positron emission tomography of tumor vasculature" (Merrill et al., 2016) [1]. Here we report biodistribution measurements in mice and calculate the radiation absorbed doses to normal organs using a modified Medical Internal Radiation Dosimetry (MIRD) methodology that accounts for physical and geometric factors and cross-organ beta doses. PMID:27014735

  16. Energy dependence of normal branch oscillations in Scorpius X-1

    NASA Astrophysics Data System (ADS)

    Wang, J.; Chang, H.-K.; Liu, C.-Y.

    2012-11-01

    We report the energy dependence of normal branch oscillations (NBOs) in Scorpius X-1, a low-mass X-ray binary Z-source. Three characteristic quantities (centroid frequency, quality factor, and fractional root-mean-squared (rms) amplitude) of a quasi-periodic oscillation signal as functions of photon energy are investigated. We found that, although it is not yet statistically well established, there is a signature indicating that the NBO centroid frequency decreases with increasing photon energy when it is below 6-8 keV, which turns out to be positively correlated with the photon energy at the higher energy side. In addition, the rms amplitude increases significantly with the photon energy below 13 keV and then decreases in the energy band of 13-20 keV. There is no clear dependence on photon energy for the quality factor. Based on these results, we suggest that the NBO originates mainly in the transition layer.

  17. Separable representation of energy-dependent optical potentials

    NASA Astrophysics Data System (ADS)

    Hlophe, L.; Elster, Ch.

    2016-03-01

    Background: One important ingredient for many applications of nuclear physics to astrophysics, nuclear energy, and stockpile stewardship are cross sections for reactions of neutrons with rare isotopes. Since direct measurements are often not feasible, indirect methods, e.g., (d ,p ) reactions, should be used. Those (d ,p ) reactions may be viewed as three-body reactions and described with Faddeev techniques. Purpose: Faddeev equations in momentum space have a long tradition of utilizing separable interactions in order to arrive at sets of coupled integral equations in one variable. Optical potentials representing the effective interactions in the neutron (proton) nucleus subsystem are usually non-Hermitian as well as energy dependent. Potential matrix elements as well as transition matrix elements calculated with them must fulfill the reciprocity theorem. The purpose of this paper is to introduce a separable, energy-dependent representation of complex, energy-dependent optical potentials that fulfill reciprocity exactly. Methods: Momentum space Lippmann-Schwinger integral equations are solved with standard techniques to obtain the form factors for the separable representation. Results: Starting from a separable, energy-independent representation of global optical potentials based on a generalization of the Ernst-Shakin-Thaler (EST) scheme, a further generalization is needed to take into account the energy dependence. Applications to n +48Ca ,n +208Pb , and p +208Pb are investigated for energies from 0 to 50 MeV with special emphasis on fulfilling reciprocity. Conclusions: We find that the energy-dependent separable representation of complex, energy-dependent phenomenological optical potentials fulfills reciprocity exactly. In addition, taking into account the explicit energy dependence slightly improves the description of the S matrix elements.

  18. Implementation of Energy-Dependent Q Values for Fission

    SciTech Connect

    Beck, B; Brown, D A; Daffin, F; Hedstrom, J; Vogt, R

    2007-08-08

    We discuss how the fission Q values for {sup 235}U, {sup 238}U and {sup 239}Pu depend on the energy of the incident neutron. We then describe how these values have been implemented in mcfgen etc. This paper describes the calculation of energy-dependent fission Q values by Madland [1] and explains how it has been implemented in the ENDL database for use in the LLNL codes.

  19. Energy dependence of the freeze out eccentricity from azimuthally-dependent HBT analyses at STAR

    NASA Astrophysics Data System (ADS)

    Anson, Christopher; STAR Collaboration

    2011-10-01

    Non-central heavy ion collisions at RHIC create an anisotropic participant zone of QCD matter under extreme conditions of energy and matter density. While this zone is initially out-of- plane-extended, pressure gradients cause the hot, dense medium to expand preferentially in plane. Over time, this expansion makes the shape more spherical, perhaps even becoming extended in the in-plane direction. The change in shape is determined by the expansion and freeze-out time scales which depend, in part, on the early pressure gradients. As a result, the freeze-out shape may provide a sensitive probe of the Equation of State of hot QCD matter. The recent RHIC Beam Energy Scan, which covered energies from √{sNN} of 7.7 to 39 GeV provides an opportunity to explore the energy dependence of the freeze out eccentricity. The new low energy data from STAR complements high statistics data sets at √{sNN} of 62.4 and 200 GeV. The dependence of the HBT radius parameters on azimuthal angle relative to the reaction plane have been extracted. These dependences can be related to the freeze out eccentricity within the context of a blast wave model. We will present STAR's most recent results from azimuthally-dependent HBT analyses across a wide range of energies.

  20. Charge state dependence of channeled ion energy loss

    NASA Astrophysics Data System (ADS)

    Golovchenko, J. A.; Goland, A. N.; Rosner, J. S.; Thorn, C. E.; Wegner, H. E.; Knudsen, H.; Moak, C. D.

    1981-02-01

    The charge state dependence of channeled ion energy loss has been determined for a series of ions ranging from fluorine to chlorine along the <110> direction in a silicon crystal. Energy losses for both bare ions and ions partially clothed with bound electrons at EA≅3 MeV/amu have been measured. The energy-loss rate for bare ions follows a strict Z21 scaling and agrees reasonably well with quantal perturbation calculations without the need for polarization or Bloch corrections. An explanation for this result is discussed. The clothed-ion energy losses appear to demonstrate screening effects that agree qualitatively with simple estimates. The angular dependence of the observed energy-loss effects is also presented.

  1. Energy-dependent effects of resveratrol in Saccharomyces cerevisiae.

    PubMed

    Madrigal-Perez, Luis Alberto; Canizal-Garcia, Melina; González-Hernández, Juan Carlos; Reynoso-Camacho, Rosalia; Nava, Gerardo M; Ramos-Gomez, Minerva

    2016-06-01

    The metabolic effects induced by resveratrol have been associated mainly with the consumption of high-calorie diets; however, its effects with standard or low-calorie diets remain unclear. To better understand the interactions between resveratrol and cellular energy levels, we used Saccharomyces cerevisiae as a model. Herein it is shown that resveratrol: (a) decreased cell viability in an energy-dependent manner; (b) lessening of cell viability occurred specifically when cells were under cellular respiration; and (c) inhibition of oxygen consumption in state 4 occurred at low and standard energy levels, whereas at high energy levels oxygen consumption was promoted. These findings indicate that the effects of resveratrol are dependent on the cellular energy status and linked to metabolic respiration. Importantly, our study also revealed that S. cerevisiae is a suitable and useful model to elucidate the molecular targets of resveratrol under different nutritional statuses. Copyright © 2016 John Wiley & Sons, Ltd.

  2. Material identification based upon energy-dependent attenuation of neutrons

    DOEpatents

    Marleau, Peter

    2015-10-06

    Various technologies pertaining to identifying a material in a sample and imaging the sample are described herein. The material is identified by computing energy-dependent attenuation of neutrons that is caused by presence of the sample in travel paths of the neutrons. A mono-energetic neutron generator emits the neutron, which is downscattered in energy by a first detector unit. The neutron exits the first detector unit and is detected by a second detector unit subsequent to passing through the sample. Energy-dependent attenuation of neutrons passing through the sample is computed based upon a computed energy of the neutron, wherein such energy can be computed based upon 1) known positions of the neutron generator, the first detector unit, and the second detector unit; or 2) computed time of flight of neutrons between the first detector unit and the second detector unit.

  3. Transport of hydrogen in metals with occupancy dependent trap energies

    SciTech Connect

    Schmid, K. Toussaint, U. von; Schwarz-Selinger, T.

    2014-10-07

    Common diffusion trapping models for modeling hydrogen transport in metals are limited to traps with single de-trapping energies and a saturation occupancy of one. While they are successful in predicting typical mono isotopic ion implantation and thermal degassing experiments, they fail at describing recent experiments on isotope exchange at low temperatures. This paper presents a new modified diffusion trapping model with fill level dependent de-trapping energies that can also explain these new isotope exchange experiments. Density function theory (DFT) calculations predict that even mono vacancies can store between 6 and 12 H atoms with de-trapping energies that depend on the fill level of the mono vacancy. The new fill level dependent diffusion trapping model allows to test these DFT results by bridging the gap in length and time scale between DFT calculations and experiment.

  4. Normalization of energy-dependent gamma survey data.

    PubMed

    Whicker, Randy; Chambers, Douglas

    2015-05-01

    Instruments and methods for normalization of energy-dependent gamma radiation survey data to a less energy-dependent basis of measurement are evaluated based on relevant field data collected at 15 different sites across the western United States along with a site in Mongolia. Normalization performance is assessed relative to measurements with a high-pressure ionization chamber (HPIC) due to its "flat" energy response and accurate measurement of the true exposure rate from both cosmic and terrestrial radiation. While analytically ideal for normalization applications, cost and practicality disadvantages have increased demand for alternatives to the HPIC. Regression analysis on paired measurements between energy-dependent sodium iodide (NaI) scintillation detectors (5-cm by 5-cm crystal dimensions) and the HPIC revealed highly consistent relationships among sites not previously impacted by radiological contamination (natural sites). A resulting generalized data normalization factor based on the average sensitivity of NaI detectors to naturally occurring terrestrial radiation (0.56 nGy hHPIC per nGy hNaI), combined with the calculated site-specific estimate of cosmic radiation, produced reasonably accurate predictions of HPIC readings at natural sites. Normalization against two to potential alternative instruments (a tissue-equivalent plastic scintillator and energy-compensated NaI detector) did not perform better than the sensitivity adjustment approach at natural sites. Each approach produced unreliable estimates of HPIC readings at radiologically impacted sites, though normalization against the plastic scintillator or energy-compensated NaI detector can address incompatibilities between different energy-dependent instruments with respect to estimation of soil radionuclide levels. The appropriate data normalization method depends on the nature of the site, expected duration of the project, survey objectives, and considerations of cost and practicality.

  5. Stress versus temperature dependent activation energies in creep

    NASA Technical Reports Server (NTRS)

    Freed, A. D.; Raj, S. V.; Walker, K. P.

    1990-01-01

    The activation energy for creep at low stresses and elevated temperatures is lattice diffusion, where the rate controlling mechanism for deformation is dislocation climb. At higher stresses and intermediate temperatures, the rate controlling mechanism changes from that of dislocation climb to one of obstacle-controlled dislocation glide. Along with this change, there occurs a change in the activation energy. It is shown that a temperature-dependent Gibbs free energy does a good job of correlating steady-state creep data, while a stress-dependent Gibbs free energy does a less desirable job of correlating the same data. Applications are made to copper and a LiF-22 mol. percent CaF2 hypereutectic salt.

  6. Stress versus temperature dependence of activation energies for creep

    NASA Technical Reports Server (NTRS)

    Freed, A. D.; Raj, S. V.; Walker, K. P.

    1992-01-01

    The activation energy for creep at low stresses and elevated temperatures is associated with lattice diffusion, where the rate controlling mechanism for deformation is dislocation climb. At higher stresses and intermediate temperatures, the rate controlling mechanism changes from dislocation climb to obstacle-controlled dislocation glide. Along with this change in deformation mechanism occurs a change in the activation energy. When the rate controlling mechanism for deformation is obstacle-controlled dislocation glide, it is shown that a temperature-dependent Gibbs free energy does better than a stress-dependent Gibbs free energy in correlating steady-state creep data for both copper and LiF-22mol percent CaF2 hypereutectic salt.

  7. Temperature dependent energy levels of methylammonium lead iodide perovskite

    SciTech Connect

    Foley, Benjamin J.; Marlowe, Daniel L.; Choi, Joshua J. E-mail: mgupta@virginia.edu; Sun, Keye; Gupta, Mool C. E-mail: mgupta@virginia.edu; Saidi, Wissam A.; Scudiero, Louis E-mail: mgupta@virginia.edu

    2015-06-15

    Temperature dependent energy levels of methylammonium lead iodide are investigated using a combination of ultraviolet photoemission spectroscopy and optical spectroscopy. Our results show that the valence band maximum and conduction band minimum shift down in energy by 110 meV and 77 meV as temperature increases from 28 °C to 85 °C. Density functional theory calculations using slab structures show that the decreased orbital splitting due to thermal expansion is a major contribution to the experimentally observed shift in energy levels. Our results have implications for solar cell performance under operating conditions with continued sunlight exposure and increased temperature.

  8. Monte Carlo Simulations on Neutron Transport and Absorbed Dose in Tissue-Equivalent Phantoms Exposed to High-Flux Epithermal Neutron Beams

    NASA Astrophysics Data System (ADS)

    Bartesaghi, G.; Gambarini, G.; Negri, A.; Carrara, M.; Burian, J.; Viererbl, L.

    2010-04-01

    Presently there are no standard protocols for dosimetry in neutron beams for boron neutron capture therapy (BNCT) treatments. Because of the high radiation intensity and of the presence at the same time of radiation components having different linear energy transfer and therefore different biological weighting factors, treatment planning in epithermal neutron fields for BNCT is usually performed by means of Monte Carlo calculations; experimental measurements are required in order to characterize the neutron source and to validate the treatment planning. In this work Monte Carlo simulations in two kinds of tissue-equivalent phantoms are described. The neutron transport has been studied, together with the distribution of the boron dose; simulation results are compared with data taken with Fricke gel dosimeters in form of layers, showing a good agreement.

  9. Energy dependence of pion inelastic scattering from sup 208 Pb

    SciTech Connect

    Oakley, D.S. Lewis and Clark College, Portland, Oregon ); Peterson, R.J. ); Seestrom, S.J.; Morris, C.L.; Plum, M.A. ); Zumbro, J.D. ); Williams, A.L.; Bryan, M.A.; McDonald, J.W.; Moore, C.F. )

    1991-11-01

    Differential cross sections were measured for pion elastic and inelastic scattering from {sup 208}Pb at {ital T}{sub {pi}}=120 and 250 MeV. Energy-dependent neutron- and proton-transition matrix elements for a range of excited states were extracted and tested for consistency, using several structure models.

  10. Efficiencies of thermodynamics when temperature-dependent energy levels exist.

    PubMed

    Yamano, Takuya

    2016-03-14

    Based on a generalized form of the second law of thermodynamics, in which the temperature-dependent energy levels of a system are appropriately included in entropy generation, we show that the effect reasonably appears in efficiencies of thermodynamic processes. PMID:26890276

  11. Energy-Dependent Fission Q Values Generalized for All Actinides

    SciTech Connect

    Vogt, R

    2008-09-25

    We generalize Madland's parameterization of the energy release in fission to obtain the dependence of the fission Q values on incident neutron energy, E{sub n}, for all major and minor actinides. These Q(E{sub n}) parameterizations are included in the ENDL2008 release. This paper describes calculations of energy-dependent fission Q values based on parameterizations of the prompt energy release in fission [1], developed by Madland [1] to describe the prompt energy release in neutron-induced fission of {sup 235}U, {sup 238}U, and {sup 239}Pu. The energy release is then related to the energy deposited during fission so that experimentally measurable quantities can be used to obtain the Q values. A discussion of these specific parameterizations and their implementation in the processing code for Monte Carlo neutron transport, MCFGEN, [2] is described in Ref. [3]. We extend this model to describe Q(E) for all actinides, major and minor, in the Evaluated Nuclear Data Library (ENDL) 2008 release, ENDL2008.

  12. Path dependence in energy systems and economic development

    NASA Astrophysics Data System (ADS)

    Fouquet, Roger

    2016-08-01

    Energy systems are subject to strong and long-lived path dependence, owing to technological, infrastructural, institutional and behavioural lock-ins. Yet, with the prospect of providing accessible cheap energy to stimulate economic development and reduce poverty, governments often invest in large engineering projects and subsidy policies. Here, I argue that while these may achieve their objectives, they risk locking their economies onto energy-intensive pathways. Thus, particularly when economies are industrializing, and their energy systems are being transformed and are not yet fully locked-in, policymakers should take care before directing their economies onto energy-intensive pathways that are likely to be detrimental to their long-run prosperity.

  13. Assessment of the accuracy of an MCNPX-based Monte Carlo simulation model for predicting three-dimensional absorbed dose distributions

    PubMed Central

    Titt, U; Sahoo, N; Ding, X; Zheng, Y; Newhauser, W D; Zhu, X R; Polf, J C; Gillin, M T; Mohan, R

    2014-01-01

    In recent years, the Monte Carlo method has been used in a large number of research studies in radiation therapy. For applications such as treatment planning, it is essential to validate the dosimetric accuracy of the Monte Carlo simulations in heterogeneous media. The AAPM Report no 105 addresses issues concerning clinical implementation of Monte Carlo based treatment planning for photon and electron beams, however for proton-therapy planning, such guidance is not yet available. Here we present the results of our validation of the Monte Carlo model of the double scattering system used at our Proton Therapy Center in Houston. In this study, we compared Monte Carlo simulated depth doses and lateral profiles to measured data for a magnitude of beam parameters. We varied simulated proton energies and widths of the spread-out Bragg peaks, and compared them to measurements obtained during the commissioning phase of the Proton Therapy Center in Houston. Of 191 simulated data sets, 189 agreed with measured data sets to within 3% of the maximum dose difference and within 3 mm of the maximum range or penumbra size difference. The two simulated data sets that did not agree with the measured data sets were in the distal falloff of the measured dose distribution, where large dose gradients potentially produce large differences on the basis of minute changes in the beam steering. Hence, the Monte Carlo models of medium- and large-size double scattering proton-therapy nozzles were valid for proton beams in the 100 MeV–250 MeV interval. PMID:18670050

  14. Dose equivalent near the bone-soft tissue interface from nuclear fragments produced by high-energy protons

    NASA Technical Reports Server (NTRS)

    Shavers, M. R.; Poston, J. W.; Cucinotta, F. A.; Wilson, J. W.

    1996-01-01

    During manned space missions, high-energy nucleons of cosmic and solar origin collide with atomic nuclei of the human body and produce a broad linear energy transfer spectrum of secondary particles, called target fragments. These nuclear fragments are often more biologically harmful than the direct ionization of the incident nucleon. That these secondary particles increase tissue absorbed dose in regions adjacent to the bone-soft tissue interface was demonstrated in a previous publication. To assess radiological risks to tissue near the bone-soft tissue interface, a computer transport model for nuclear fragments produced by high energy nucleons was used in this study to calculate integral linear energy transfer spectra and dose equivalents resulting from nuclear collisions of 1-GeV protons transversing bone and red bone marrow. In terms of dose equivalent averaged over trabecular bone marrow, target fragments emitted from interactions in both tissues are predicted to be at least as important as the direct ionization of the primary protons-twice as important, if recently recommended radiation weighting factors and "worst-case" geometry are used. The use of conventional dosimetry (absorbed dose weighted by aa linear energy transfer-dependent quality factor) as an appropriate framework for predicting risk from low fluences of high-linear energy transfer target fragments is discussed.

  15. Time dependence of energy storage across multiple ecosystems

    NASA Astrophysics Data System (ADS)

    Reed, D. E.; Frank, J. M.; Ewers, B. E.; Desai, A. R.

    2015-12-01

    Energy flow through ecosystems plays a critical role in processes at multiple spatial and temporal scales, from monthly growing season length of landscapes to sub-diurnal responses of soil respiration to temperature, photosynthesis and water inputs. The interaction of solar radiation and ecosystems is complex with terrestrial canopies and aquatic structure both connecting above- and below-ground processes via energy fluxes. Previous work by Leuning et al has shown that at 30-minute timescales, only 8% of eddy covariance sites in the La Thuile dataset observe energy closure and when averaged to 24-hour timescales, this goes up to 45%. This work examines the effect of temporal lags in energy storage in both terrestrial (shrub and forest) and aquatic (lake) ecosystems. Analyses show energy storage terms have unique temporal lags that vary between ecosystem and time of year, from having zero lag to several hour timescales within terrestrial ecosystems, depending primarily on water content. Large differences between ecosystem types are also highlighted as aquatic ecosystems have lags that range between daily and monthly timescales. Furthermore, ecosystem disturbance can alter time lags as well and results from a native bark beetle disturbance show vegetation lag decreasing while soil lag increasing following changes in water content. Energy storage lags can improve site energy closure by several percent, and these results will lead to a better understanding of surface energy budget closure, an as-of-yet unresolved issue in the flux community, as well as highlighting the importance of time-dependency of ecosystem energy fluxes as a unique method to examine ecosystem processes.

  16. Divergences in the vacuum energy for frequency-dependent interactions

    NASA Astrophysics Data System (ADS)

    Vassilevich, D. V.

    2009-03-01

    We propose a method for determining ultraviolet divergences in the vacuum energy for systems whose spectrum of perturbations is defined through a nonlinear spectrum problem, i.e., when the fluctuation operator itself depends on the frequency. The method is applied to the plasma shell model, which describes some properties of the interaction of electromagnetic field with fullerenes. We formulate a scalar model, which simplifies the matrix structure, but keeps the frequency dependence of the plasma shell, and calculate the ultraviolet divergences in the case when the plasma sheet is slightly curved. The divergent terms are expressed in terms of surface integrals of corresponding invariants.

  17. Dependability of wind energy generators with short-term energy storage.

    PubMed

    Sørensen, B

    1976-11-26

    Power fluctuations and power duration curves for wind energy generators, including energy storage facilities of a certain capacity, are compared to those of typical nuclear reactors. A storage system capable of delivering the yearly average power output for about 10 hours already makes the dependability of the wind energy system comparable to that of a typical nuclear plant.

  18. Distributed energy storage: Time-dependent tree flow design

    NASA Astrophysics Data System (ADS)

    Bejan, A.; Ziaei, S.; Lorente, S.

    2016-05-01

    This article proposes "distributed energy storage" as a basic design problem of distributing energy storage material on an area. The energy flows by fluid flow from a concentrated source to points (users) distributed equidistantly on the area. The flow is time-dependent. Several scenarios are analyzed: sensible-heat storage, latent-heat storage, exergy storage vs energy storage, and the distribution of a finite supply of heat transfer surface between the source fluid and the distributed storage material. The chief conclusion is that the finite amount of storage material should be distributed proportionally with the distribution of the flow rate of heating agent arriving on the area. The total time needed by the source stream to "invade" the area is cumulative (the sum of the storage times required at each storage site) and depends on the energy distribution paths and the sequence in which the users are served by the source stream. Directions for future designs of distributed storage and retrieval are outlined in the concluding section.

  19. Generalized Energy-Dependent Q Values for Fission

    SciTech Connect

    Vogt, R

    2010-03-31

    We extend Madland's parameterization of the energy release in fission to obtain the dependence of the fission Q value for major and minor actinides on the incident neutron energies in the range 0 {le} E{sub n} {le} 20 MeV. Our parameterization is based on the actinide evaluations recommended for the ENDF/B-VII.1 release. This paper describes the calculation of energydependent fission Q values based on the calculation of the prompt energy release in fission by Madland. This calculation was adopted for use in the LLNL ENDL database and then generalized to obtain the prompt fission energy release for all actinides. Here the calculation is further generalized to the total energy release in fission. There are several stages in a fission event, depending on the time scale. Neutrons and gammas may be emitted at any time during the fission event.While our discussion here is focussed on compound nucleus creation by an incident neutron, similar parameterizations could be obtained for incident gammas or spontaneous fission.

  20. Energy dependence of the freeze-out eccentricity from the azimuthal dependence of HBT at STAR

    NASA Astrophysics Data System (ADS)

    Anson, Christopher; STAR Collaboration

    2011-12-01

    Non-central heavy-ion collisions create an out-of-plane-extended participant zone that expands toward a more round state as the system evolves. The recent RHIC beam energy scan at \\sqrt{s_{NN}} of 7.7, 11.5 and 39 GeV provides an opportunity to explore the energy dependence of the freeze-out eccentricity. The new low-energy data from STAR complement high statistics data sets at \\sqrt{s_{NN}} of 62.4 and 200 GeV. Hanbury Brown-Twiss (HBT) interferometry allows us to determine the size of pion-emitting source regions. The dependence of the HBT radius parameters on the azimuthal angle relative to the reaction plane has been extracted. These dependences can be related to the freeze-out eccentricity. The new results from STAR are consistent with a monotonically decreasing freeze-out eccentricity and constrain any minimum, suggested by previously available data, to lie in the range between 11.5 and 39 GeV. Of several models, UrQMD appears to best predict the STAR and AGS data.

  1. Energy and rapidity dependence of beauty production at Tevatron

    SciTech Connect

    Ba, M.M.

    1997-09-01

    The CDF and D0 experiments have measured bb production in pp interactions at {radical}s = 1800 GeV and 630 GeV (the energy at which the previous measurement was performed by the UAl experiment). The Tevatron measurements are used to evaluate, for the first time, the center-of-mass energy and rapidity dependence of b-quark production cross section measured with the same detectors. Preliminary results from these measurements are presented and compared with the next-to-leading order QCD predictions.

  2. HZEFRG1: An energy-dependent semiempirical nuclear fragmentation model

    NASA Technical Reports Server (NTRS)

    Townsend, Lawrence W.; Wilson, John W.; Tripathi, Ram K.; Norbury, John W.; Badavi, Francis F.; Khan, Ferdous

    1993-01-01

    Methods for calculating cross sections for the breakup of high-energy heavy ions by the combined nuclear and coulomb fields of the interacting nuclei are presented. The nuclear breakup contributions are estimated with an abrasion-ablation model of heavy ion fragmentation that includes an energy-dependent, mean free path. The electromagnetic dissociation contributions arising from the interacting coulomb fields are estimated by using Weizsacker-Williams theory extended to include electric dipole and electric quadrupole contributions. The complete computer code that implements the model is included as an appendix. Extensive comparisons of cross section predictions with available experimental data are made.

  3. Key comparison BIPM.RI(I)-K6 of the standards for absorbed dose to water at 10 g cm-2 of the NMIJ, Japan and the BIPM in accelerator photon beams

    NASA Astrophysics Data System (ADS)

    Picard, S.; Burns, D. T.; Roger, P.; Shimizu, M.; Morishita, Y.; Kato, M.; Tanaka, T.; Kurosawa, T.; Saito, N.

    2016-01-01

    A comparison of the dosimetry for accelerator photon beams was carried out between the National Metrology Institute of Japan (NMIJ) and the Bureau International des Poids et Mesures (BIPM) from 9 to 23 April 2015. The comparison was based on the determination of absorbed dose to water at 10 g cm-2 for three radiation qualities at the NMIJ. The results, reported as ratios of the NMIJ and the BIPM evaluations (and with the combined standard uncertainties given in parentheses), are 0.9966 (47) at 6 MV, 0.9965 (60) at 10 MV and 0.9953 (50) at 15 MV. This result is the eighth in the on-going BIPM.RI(I)-K6 series of comparisons. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

  4. Parametric dependence of energy harvesting performance with an oscillating hydrofoil

    NASA Astrophysics Data System (ADS)

    Strom, Benjamin; Kim, Daegyoum; Mandre, Shreyas; Breuer, Kenneth

    2014-11-01

    We report on experiments on tidal energy conversion from a open channel water flow using an oscillating hydrofoil. The hydrofoil is operated at high angles of attack such that the formation and capture of a leading edge vortex greatly enhances the energy conversion efficiency. A computer-controlled pitch and heave system allows for arbitrary position profiles to be imposed. Force and torque measurements are used to determine the energy harvesting efficiency as a function of Reynolds number, pitch and heave amplitudes, phase shift, the location of the pitching axis, position profile, and the cross sectional shape of the hydrofoil. PIV measurements are used to capture the vortex dynamics and these results are compared to the computational results of Frank and Franck (2013). Efficiency was found to be most sensitive to pitch amplitude, pitching axis and phase shift with relatively little dependence on Reynolds number, heave amplitude, and foil shape. Work supported by DOE-ARPAe.

  5. Relative response of the alanine dosimeter to medium energy x-rays.

    PubMed

    Anton, M; Büermann, L

    2015-08-01

    The response of the alanine dosimeter to kilovoltage x-rays with respect to the dose to water was measured, relative to the response to Co-60 radiation.Two series of x-ray qualities were investigated, one ranging from 30 kV to 100 kV tube voltage (TW series), the other one ranging from 70 kV to 280 kV (TH series). Due to the use of the water calorimeter as a primary standard, the uncertainty of the delivered dose is significantly lower than for other published data. The alanine response was measured as described in a previous publication (Anton et al 2013 Phys. Med. Biol. 58 3259-82). The uncertainty component due to the alanine measurement and analysis is ⩽0.4%, the major part of the combined uncertainty of the relative response originates from the uncertainty of the delivered dose. The relative uncertainties of the relative response vary from ⩽2% for the TW series to ⩽1.1% for the TH series.Different from the behaviour of the alanine dosimeter for megavoltage x-rays or electrons, the relative response drops significantly from unity for Co-60 radiation to less than 64% for the TW quality with a tube voltage of 30 kV. In order to reproduce this behaviour through Monte Carlo simulations, not only the ratio of the absorbed dose to alanine to the absorbed dose to water has to be known, but also the intrinsic efficiency, i.e. the dependence of the number of free radicals generated per unit of absorbed dose on the photon energy. This quantity is not yet accessible for the TW series.For a possible use of the alanine dosimeter for kilovoltage x-rays, for example in electronic brachytherapy, users should rely on the measured data for the relative response which have become available with this publication. PMID:26216572

  6. Relative response of the alanine dosimeter to medium energy x-rays

    NASA Astrophysics Data System (ADS)

    Anton, M.; Büermann, L.

    2015-08-01

    The response of the alanine dosimeter to kilovoltage x-rays with respect to the dose to water was measured, relative to the response to Co-60 radiation. Two series of x-ray qualities were investigated, one ranging from 30 kV to 100 kV tube voltage (TW series), the other one ranging from 70 kV to 280 kV (TH series). Due to the use of the water calorimeter as a primary standard, the uncertainty of the delivered dose is significantly lower than for other published data. The alanine response was measured as described in a previous publication (Anton et al 2013 Phys. Med. Biol. 58 3259-82). The uncertainty component due to the alanine measurement and analysis is ⩽0.4%, the major part of the combined uncertainty of the relative response originates from the uncertainty of the delivered dose. The relative uncertainties of the relative response vary from ⩽2% for the TW series to ⩽1.1% for the TH series. Different from the behaviour of the alanine dosimeter for megavoltage x-rays or electrons, the relative response drops significantly from unity for Co-60 radiation to less than 64% for the TW quality with a tube voltage of 30 kV. In order to reproduce this behaviour through Monte Carlo simulations, not only the ratio of the absorbed dose to alanine to the absorbed dose to water has to be known, but also the intrinsic efficiency, i.e. the dependence of the number of free radicals generated per unit of absorbed dose on the photon energy. This quantity is not yet accessible for the TW series. For a possible use of the alanine dosimeter for kilovoltage x-rays, for example in electronic brachytherapy, users should rely on the measured data for the relative response which have become available with this publication.

  7. Relative response of the alanine dosimeter to medium energy x-rays.

    PubMed

    Anton, M; Büermann, L

    2015-08-01

    The response of the alanine dosimeter to kilovoltage x-rays with respect to the dose to water was measured, relative to the response to Co-60 radiation.Two series of x-ray qualities were investigated, one ranging from 30 kV to 100 kV tube voltage (TW series), the other one ranging from 70 kV to 280 kV (TH series). Due to the use of the water calorimeter as a primary standard, the uncertainty of the delivered dose is significantly lower than for other published data. The alanine response was measured as described in a previous publication (Anton et al 2013 Phys. Med. Biol. 58 3259-82). The uncertainty component due to the alanine measurement and analysis is ⩽0.4%, the major part of the combined uncertainty of the relative response originates from the uncertainty of the delivered dose. The relative uncertainties of the relative response vary from ⩽2% for the TW series to ⩽1.1% for the TH series.Different from the behaviour of the alanine dosimeter for megavoltage x-rays or electrons, the relative response drops significantly from unity for Co-60 radiation to less than 64% for the TW quality with a tube voltage of 30 kV. In order to reproduce this behaviour through Monte Carlo simulations, not only the ratio of the absorbed dose to alanine to the absorbed dose to water has to be known, but also the intrinsic efficiency, i.e. the dependence of the number of free radicals generated per unit of absorbed dose on the photon energy. This quantity is not yet accessible for the TW series.For a possible use of the alanine dosimeter for kilovoltage x-rays, for example in electronic brachytherapy, users should rely on the measured data for the relative response which have become available with this publication.

  8. Tension-Dependent Free Energies of Nucleosome Unwrapping

    PubMed Central

    2016-01-01

    Nucleosomes form the basic unit of compaction within eukaryotic genomes, and their locations represent an important, yet poorly understood, mechanism of genetic regulation. Quantifying the strength of interactions within the nucleosome is a central problem in biophysics and is critical to understanding how nucleosome positions influence gene expression. By comparing to single-molecule experiments, we demonstrate that a coarse-grained molecular model of the nucleosome can reproduce key aspects of nucleosome unwrapping. Using detailed simulations of DNA and histone proteins, we calculate the tension-dependent free energy surface corresponding to the unwrapping process. The model reproduces quantitatively the forces required to unwrap the nucleosome and reveals the role played by electrostatic interactions during this process. We then demonstrate that histone modifications and DNA sequence can have significant effects on the energies of nucleosome formation. Most notably, we show that histone tails contribute asymmetrically to the stability of the outer and inner turn of nucleosomal DNA and that depending on which histone tails are modified, the tension-dependent response is modulated differently. PMID:27725965

  9. Energy Dependent Bias in the Weighted Point Model.

    SciTech Connect

    Santi, P. A.; Geist, W. H.

    2005-01-01

    While the weighted point multiplicity model has successfully reduced the bias that is associated with variable multiplication of neutrons within a sample (which was assumed constant in the standard point multiplicity model), other potential sources of bias still exists within the weighted point model. One significant source of bias arises from the assumption that the energies of the neutrons from ({alpha},n) reactions on impurities in the sample have the same average energy as neutrons emitted from the spontaneous fission of {sup 240}Pu. An investigation into the effects that neutron energy has on the assay results (effective {sup 240}Pu mass, alpha, and multiplication) of the weighted point multiplicity model has been performed using MCNPX, Version 2.5f for impure plutonium metal samples in a number of different detector systems. The effects of energy dependence of the detection efficiency and gate fractions on the assay results, as well as the measured singles, doubles, and triples rates were also studied. Methods for mitigating the effects of neutron energy on the weighted-point multiplicity model results will be presented and discussed.

  10. Orientation-dependent binding energy of graphene on palladium

    NASA Astrophysics Data System (ADS)

    Kappes, Branden B.; Ebnonnasir, Abbas; Kodambaka, Suneel; Ciobanu, Cristian V.

    2013-02-01

    Using density functional theory calculations, we show that the binding strength of a graphene monolayer on Pd(111) can vary between physisorption and chemisorption depending on its orientation. By studying the interfacial charge transfer, we have identified a specific four-atom carbon cluster that is responsible for the local bonding of graphene to Pd(111). The areal density of such clusters varies with the in-plane orientation of graphene, causing the binding energy to change accordingly. Similar investigations can also apply to other metal substrates and suggests that physical, chemical, and mechanical properties of graphene may be controlled by changing its orientation.

  11. Orientation-dependent binding energy of graphene on palladium

    SciTech Connect

    Kappes, Branden B.; Ebnonnasir, Abbas; Ciobanu, Cristian V.; Kodambaka, Suneel

    2013-02-04

    Using density functional theory calculations, we show that the binding strength of a graphene monolayer on Pd(111) can vary between physisorption and chemisorption depending on its orientation. By studying the interfacial charge transfer, we have identified a specific four-atom carbon cluster that is responsible for the local bonding of graphene to Pd(111). The areal density of such clusters varies with the in-plane orientation of graphene, causing the binding energy to change accordingly. Similar investigations can also apply to other metal substrates and suggests that physical, chemical, and mechanical properties of graphene may be controlled by changing its orientation.

  12. Energy dependent growth of nucleon and inclusive charged hadron distributions

    NASA Astrophysics Data System (ADS)

    Wang, Hong-Min; Hou, Zhao-Yu; Sun, Xian-Jing

    2015-11-01

    In the Color Glass Condensate formalism, charged hadron pT spectra in p+p and p+Pb collisions are studied by considering an energy-dependent broadening of nucleon density distribution. Then, in the glasma flux tube picture, the n-particle multiplicity distributions at different pseudo-rapidity ranges are investigated. Both the theoretical results show good agreement with the recent experimental data from ALICE and CMS at LHC energies. The predictive results for pT or multiplicity distributions in p+p and p+Pb collisions at the Large Hadron Collider are also given in this paper. Supported by Natural Science Foundation of Hebei Province (A2012210043)

  13. Low barrier kinetics: dependence on observables and free energy surface.

    PubMed

    Ma, Hairong; Gruebele, Martin

    2006-01-30

    Dynamics on free energy surfaces with high activation barriers are usually treated by few-state kinetics models, yielding characteristic rate coefficients and amplitudes depending on the connectivity of the states. When the barriers are low (< 3 kT), the assumption of instantaneous equilibration of the transition state, and hence, the few-state kinetics treatment, break down. Langevin dynamics is used here to explore the characteristic trends that occur in such cases, as a function of barrier height, number of barriers, dimensionality of the free energy surface, and switching functions that describe how spectroscopic probes vary from reactant to product. The result is a systematic phenomenological description of low barrier kinetics and dynamics.

  14. SU-F-BRE-15: Verification of Energy Dependence of MAGAT Polymer Gel at Orthovoltage Energies

    SciTech Connect

    Roed, Y; Tailor, R; Ibbott, G; Pinsky, L

    2014-06-15

    Purpose: Investigation of dose response curves of methacrylic acid-based “MAGAT” gel at different effective energies to verify an energy dependence of polymer-gel dosimeters for orthovoltage energy x-rays. Methods: Six small cylindrical MAGAT gel phantoms were exposed to different dose levels; one phantom was unirradiated for background subtraction. This experiment was repeated for three different effective beam energies.24 h post irradiation the spin-spin relaxation times (T2) were measured with a 4.7 T Bruker MR scanner at 2 cm depth inside the gel. The T2 values were converted to relaxation rates (R2) and plotted against the respective dose levels corresponding to the different effective energies. The resulting dose response curves were compared for a 250 kVp beam, the 250 kVp beam filtered by 6 cm of water, and a 125 kVp beam. Results: The passage of the 250 kVp beam through water resulted in a half-value-layer (HVL) change from 1.05 mm Cu to 1.32 mm Cu at 6 cm depth with a change in effective energy from 81.3 keV to 89.5 keV, respectively. The dose response curves showed a shift to higher relaxation rates for the harder beam. The dose response measurements for the 125 kVp beam (HVL: 3.13 mm Al, effective energy: 33.9 keV) demonstrated even higher relaxation rates than for either of the other beams. Conclusion: The MAGAT dose response curves for three different effective energies demonstrate a complex energy dependence, with an apparent decrease in sensitivity at 89.5 keV effective energy. This energy dependence is consistent with observed discrepancies of depth dose data compared with ion-chamber data. For future investigations of larger volumes, an energy-dependent sensitivity function is needed to properly assess 3-dimensional dose distributions.

  15. Observation of Field-Emission Dependence on Stored Energy

    NASA Astrophysics Data System (ADS)

    Shao, Jiahang; Antipov, Sergey P.; Baryshev, Sergey V.; Chen, Huaibi; Conde, Manoel; Doran, Darrell S.; Gai, Wei; Jing, Chunguang; Liu, Wanming; Power, John; Qiu, Jiaqi; Shi, Jiaru; Wang, Dan; Wang, Faya; Whiteford, Charles E.; Wisniewski, Eric; Xiao, Liling

    2015-12-01

    Field emission from a solid metal surface has been continuously studied for a century over macroscopic to atomic scales. It is general knowledge that, other than the surface properties, the emitted current is governed solely by the applied electric field. A pin cathode has been used to study the dependence of field emission on stored energy in an L -band rf gun. The stored energy was changed by adjusting the axial position (distance between the cathode base and the gun back surface) of the cathode while the applied electric field on the cathode tip is kept constant. A very strong correlation of the field-emission current with the stored energy has been observed. While eliminating all possible interfering sources, an enhancement of the current by a factor of 5 was obtained as the stored energy was increased by a factor of 3. It implies that under certain circumstances a localized field emission may be significantly altered by the global parameters in a system.

  16. Observation of Field-Emission Dependence on Stored Energy.

    PubMed

    Shao, Jiahang; Antipov, Sergey P; Baryshev, Sergey V; Chen, Huaibi; Conde, Manoel; Doran, Darrell S; Gai, Wei; Jing, Chunguang; Liu, Wanming; Power, John; Qiu, Jiaqi; Shi, Jiaru; Wang, Dan; Wang, Faya; Whiteford, Charles E; Wisniewski, Eric; Xiao, Liling

    2015-12-31

    Field emission from a solid metal surface has been continuously studied for a century over macroscopic to atomic scales. It is general knowledge that, other than the surface properties, the emitted current is governed solely by the applied electric field. A pin cathode has been used to study the dependence of field emission on stored energy in an L-band rf gun. The stored energy was changed by adjusting the axial position (distance between the cathode base and the gun back surface) of the cathode while the applied electric field on the cathode tip is kept constant. A very strong correlation of the field-emission current with the stored energy has been observed. While eliminating all possible interfering sources, an enhancement of the current by a factor of 5 was obtained as the stored energy was increased by a factor of 3. It implies that under certain circumstances a localized field emission may be significantly altered by the global parameters in a system. PMID:26764996

  17. Frequency-dependent energy harvesting via magnetic shape memory alloys

    NASA Astrophysics Data System (ADS)

    Sayyaadi, Hassan; Askari Farsangi, Mohammad Amin

    2015-11-01

    This paper is focused on presenting an accurate framework to describe frequency-dependent energy harvesting via magnetic shape memory alloys (MSMAs). Modeling strategy incorporates the phenomenological constitutive model developed formerly together with the magnetic diffusion equation. A hyperbolic hardening function is employed to define reorientation-induced strain hardening in the material, and the diffusion equation is used to add dynamic effects to the model. The MSMA prismatic specimen is surrounded by a pickup coil, and the induced voltage during martensite-variant reorientation is investigated with the help of Faraday’s law of magnetic field induction. It has been shown that, in order to harvest the maximum RMS voltage in the MSMA-based energy harvester, an optimum value of bias magnetic field exists, which is the corresponding magnetic field for the start of pseudoelasticity behavior. In addition, to achieve a more compact energy harvester with higher energy density, a specimen with a lower aspect ratio can be chosen. As the main novelty of the paper, it is found that the dynamic effects play a major role in determining the harvested voltage and power, especially for high excitation frequency or specimen thickness.

  18. Relativistic mean-field model with energy dependent self-energies

    SciTech Connect

    Antic, S.; Typel, S.

    2015-02-24

    Conventional relativistic mean-field theory is extended with the introduction of higher-order derivative couplings of nucleons with the meson fields. The Euler-Lagrange equations follow from the principle of stationary action. From invariance principles of the Lagrangian density the most general expressions for the conserved current and energy-momentum tensor are derived. The nucleon self-energies show the explicit dependence on the meson fields. They contain additional regulator functions which describe the energy dependence. The density dependence of meson-nucleon couplings causes the apperance of additional rearrangement contributions in the self-energies. The equation of state of infinite nuclear matter is obtained and the thermodynamical consistency of the model is demonstrated. This model is applied to the description of spherical, non-rotating stars in β-equilibrium. Stellar structure is calculated by solving the Tolman-Oppenheimer-Volkov (TOV) equations. The results for neutron stars are shown in terms of mass-radius relations.

  19. Energy-dependent volume regulation in primary cultured cerebral astrocytes.

    PubMed

    Olson, J E; Sankar, R; Holtzman, D; James, A; Fleischhacker, D

    1986-08-01

    Cell volume regulation and energy metabolism were studied in primary cultured cerebral astrocytes during exposure to media of altered osmolarity. Cells suspended in medium containing 1/2 the normal concentration of NaCl (hypoosmotic) swell immediately to a volume 40-50% larger than cells suspended in isoosmotic medium. The cell volume in hypoosmotic medium then decreases over 30 min to a volume approximately 25% larger than cells in isoosmotic medium. In hyperosmotic medium (containing twice the normal concentration of NaCl), astrocytes shrink by 29%. Little volume change occurs following this initial shrinkage. Cells resuspended in isoosmotic medium after a 30 min incubation in hypoosmotic medium shrink immediately to a volume 10% less than the volume of cells incubated continuously in isoosmotic medium. Thus, the regulatory volume decrease (RVD) in hypoosmotic medium involves a net reduction of intracellular osmoles. The RVD is partially blocked by inhibitors of mitochondrial electron transport but is unaffected by an inhibitor of glycolysis or by an uncoupler of oxidative phosphorylation. Inhibition of RVD by these metabolic agents is correlated with decreased cellular ATP levels. Ouabain, added immediately after hypoosmotic induced swelling, completely inhibits RVD, but does not alter cell volume if added after RVD has taken place. Ouabain also inhibits cell respiration 27% more in hypoosmotic medium than in isoosmotic medium indicating that the (Na,K)-ATPase-coupled ion pump is more active in the hypoosmotic medium. These data suggest that the cell volume response of astrocytes in hypoosmotic medium involves the net movement of osmoles by a mechanism dependent on cellular energy and tightly coupled to the (Na,K)-ATPase ion pump. This process may be important in the energy-dependent osmoregulation in the brain, a critical role attributed to the astrocyte in vivo. PMID:3015986

  20. Energy-dependent timing of thermal emission in solar flares

    NASA Astrophysics Data System (ADS)

    Jain, Rajmal; Rajpurohit, Arvind; Awasthi, Arun; Aschwanden, Markus

    A study of thermal emission in solar flares using high-resolution X-ray spectra observed by the Si detector onboard "Solar X-ray Spectrometer" (SOXS) has been conducted. The SOXS onboard GSAT-2 Indian spacecraft was launched by GSLV-D2 rocket on 08 May 2003. With this we investigate the energy dependent timing of thermal emission in solar flares. Firstly we model the spectral-temporal evolution of the X-ray flux F(e,t) assuming multi-temperature plasma governed by thermal conduction cooling. This model is found in agreement with the temperature and emission measure derived from the fitting of the spectra observed by the Si detector. We investigate 10 M-class flares and found that the emission in the energy range e=6 -20 keV is dominated by temperatures T=15 -50 MK while the power-law index (gamma) of the thermal spectrum varies over 2.7 -4.3. The temperature-dependent cooling time varies between 22 and 310 s. The electron density (ne) obtained for the flares under investigation ranges between 0.03 and 5X1011 cm-3 suggests that conduction cooling of thermal X-ray plasma dominates over radiative cooling in the initial phase of the flare. The current study also provides an alternative method for separating thermal from non-thermal spectra, which enables us to measure the break-energy point to be varying between 17 and 220.7 keV.

  1. Fluence correction factors for graphite calorimetry in a low-energy clinical proton beam: I. Analytical and Monte Carlo simulations.

    PubMed

    Palmans, H; Al-Sulaiti, L; Andreo, P; Shipley, D; Lühr, A; Bassler, N; Martinkovič, J; Dobrovodský, J; Rossomme, S; Thomas, R A S; Kacperek, A

    2013-05-21

    The conversion of absorbed dose-to-graphite in a graphite phantom to absorbed dose-to-water in a water phantom is performed by water to graphite stopping power ratios. If, however, the charged particle fluence is not equal at equivalent depths in graphite and water, a fluence correction factor, kfl, is required as well. This is particularly relevant to the derivation of absorbed dose-to-water, the quantity of interest in radiotherapy, from a measurement of absorbed dose-to-graphite obtained with a graphite calorimeter. In this work, fluence correction factors for the conversion from dose-to-graphite in a graphite phantom to dose-to-water in a water phantom for 60 MeV mono-energetic protons were calculated using an analytical model and five different Monte Carlo codes (Geant4, FLUKA, MCNPX, SHIELD-HIT and McPTRAN.MEDIA). In general the fluence correction factors are found to be close to unity and the analytical and Monte Carlo codes give consistent values when considering the differences in secondary particle transport. When considering only protons the fluence correction factors are unity at the surface and increase with depth by 0.5% to 1.5% depending on the code. When the fluence of all charged particles is considered, the fluence correction factor is about 0.5% lower than unity at shallow depths predominantly due to the contributions from alpha particles and increases to values above unity near the Bragg peak. Fluence correction factors directly derived from the fluence distributions differential in energy at equivalent depths in water and graphite can be described by kfl = 0.9964 + 0.0024·zw-eq with a relative standard uncertainty of 0.2%. Fluence correction factors derived from a ratio of calculated doses at equivalent depths in water and graphite can be described by kfl = 0.9947 + 0.0024·zw-eq with a relative standard uncertainty of 0.3%. These results are of direct relevance to graphite calorimetry in low-energy protons but given that the fluence

  2. Length and energy gap dependences of thermoelectricity in nanostructured junctions.

    PubMed

    Asai, Yoshihiro

    2013-04-17

    The possibilities of an enhanced thermoelectric figure of merit value, ZT, in a nanostructured junction are examined for a wide range of parameter values in a theoretical model. Our research shows that the figure of merit can take a very large maximum, which depends both on the length and the energy gap values. The maximum of ZT is achieved when the Fermi level of the electrodes is aligned to the edge of the electronic transmission function of the junction, where both the conductance and the Seebeck constant are significantly enhanced. On the basis of our results, we conclude that nanowires and molecular junctions form a special class of systems where a large ZT can be expected in some cases. PMID:23528878

  3. Energy-Dependent Reversal of the Cytochrome Oxidase Reaction

    NASA Astrophysics Data System (ADS)

    Wikstrom, Marten

    1981-07-01

    Energization of isolated rat liver mitochondria with ATP under conditions in which cytochrome c is poised in a highly oxidized state shifts the state of cytochrome oxidase (cytochrome c oxidase; ferrocytochrome c:oxygen oxidoreductase, EC 1.9.3.1) from fully oxidized to two new spectroscopically distinguishable states depending on the applied phosphorylation potential and redox potential at cytochrome c. Both new states are spectrally similar or identical to two previously described intermediates in the reaction between reduced enzyme and O2. The data suggest that the energy-dependent transitions are due to reversed electron transfer from water to ferricytochrome c linked to accumulation of intermediates of O2 reduction at the catalytic heme a3/copper center. Titrations with redox potential indicate that each transition is a one-electron step, a finding that would identify the second observed compound as enzyme-bound peroxide or its equivalent. This is consistent with this compound being spectrally identical to ``Compound C,'' previously described as the reaction product between half-reduced oxidase (two electrons) and O2. On the basis of these data a catalytic scheme of O2 reduction is proposed for the heme a3/copper center of cytochrome oxidase.

  4. Energy-dependent characteristics of collisinal vibration-energy exchange in vapors of polyatomic molcules

    SciTech Connect

    Zalesskaya, G.A.; Yakovlev, D.L.

    1995-02-01

    CO{sub 2} laser-induced delayed fluorescence was used to study the collisional vibration-energy exchange between the polyatomic molecules in gases. The efficiency of collisional exchange, the mean amount of energy transfer in one collision, as well as their correlation with the vibration energy and with the size of excited molecule were determined for diacetyl, acetophenone, benzophenone, and anthraquinone molecules form the experimentally observed pressure dependences of the decay rates and fluorescence intensities. It was shown that the mean amount of energy transfer per collision decreases with the molecular size and increases as E{sup m}, with m>2, with increasing the vibration energy. 25 refs., 4 figs., 1 tab.

  5. Energy dependence of response of new high sensitivity radiochromic films for megavoltage and kilovoltage radiation energies

    SciTech Connect

    Chiu-Tsao, S.-T.; Ho Yunsil; Shankar, Ravi; Wang Lin; Harrison, Louis B.

    2005-11-15

    The purpose of this paper is to evaluate the energy dependence of the response of two new high sensitivity models of radiochromic films EBT and XR-QA. We determined the dose response curves of these films for four different radiation sources, namely, 6 MV photon beams (6 MVX), Ir-192, I-125, and Pd-103. The first type (EBT) is designed for intensity modulated radiation therapy (IMRT) dosimetry, and the second type (XR-QA) is designed for kilovoltage dosimetry. All films were scanned using red (665 nm) and green (520 nm) light sources in a charge-coupled device-based densitometer. The dose response curves [net optical density (NOD) versus dose] were plotted and compared for different radiation energies and light sources. Contrary to the early GAFCHROMIC film types (such as models XR, HS, MD55-2, and HD810), the net optical densities of both EBT and XR-QA were higher with a green (520 nm) than those with a red (665 nm) light source due to the different absorption spectrum of the new radiochromic emulsion. Both film types yield measurable optical densities for doses below 2 Gy. EBT film response is nearly independent of radiation energy, within the uncertainty of measurement. The NOD values of EBT film at 1 and 2 Gy are 0.13 and 0.25 for green, and 0.1 and 0.17 for red, respectively. In contrast, the XR-QA film sensitivity varies with radiation energy. The doses required to produce NOD of 0.5 are 6.9, 5.4, 0.7, and 0.9 Gy with green light and 19, 13, 1.7, and 1.5 Gy with red light, for 6 MVX, Ir-192, I-125, and Pd-103, respectively. EBT film was found to have minimal photon energy dependence of response for the energies tested and is suitable for dosimetry of radiation with a wide energy spectrum, including primary and scattered radiation. XR-QA film is promising for kilovoltage sources with a narrow energy spectra. The new high sensitivity radiochromic films are promising tools in radiation dosimetry.

  6. Energy Dependence of Crystal Assisted Extraction at the CERN SPS

    NASA Astrophysics Data System (ADS)

    Herr, W.; Elsener, K.; Fidecaro, G.; Gyr, M.; Klem, J.; Weisse, E.

    1997-05-01

    The feasibility of extracting particles from a halo of a circulating proton beam has been successfully demonstrated experimentally at the SPS. Although most measurements were obtained at an intermediate energy of 120 GeV, more recently we had the unique opportunity to extract protons from a coasting beam at 14 GeV and 270 GeV, thus exploiting the full available energy range of the SPS. In this report we present a comparison of the measurements at the three energies and a qualitative comparison with the predictions.

  7. Isospin effects on the mass dependence of the balance energy

    SciTech Connect

    Gautam, Sakshi; Sood, Aman D.

    2010-07-15

    We study the effect of isospin degree of freedom on balance energy throughout the mass range between 50 and 350 for two sets of isotopic systems with N/A= 0.54 and 0.57 as well as isobaric systems with N/A= 0.5 and 0.58. Our findings indicate that different values of balance energy for two isobaric systems may be mainly due to the Coulomb repulsion. We also demonstrate clearly the dominance of Coulomb repulsion over symmetry energy.

  8. Excitation energy dependent Raman spectrum of MoSe2

    PubMed Central

    Nam, Dahyun; Lee, Jae-Ung; Cheong, Hyeonsik

    2015-01-01

    Raman investigation of MoSe2 was carried out with eight different excitation energies. Seven peaks, including E1g, A1g, E2g1, and A2u2 peaks are observed in the range of 100–400 cm−1. The phonon modes are assigned by comparing the peak positions with theoretical calculations. The intensities of the peaks are enhanced at different excitation energies through resonance with different optical transitions. The A1g mode is enhanced at 1.58 and 3.82 eV, which are near the A exciton energy and the band-to-band transition between higher energy bands, respectively. The E2g1 mode is strongly enhanced with respect to the A1g mode for the 2.71- and 2.81-eV excitations, which are close to the C exciton energy. The different enhancements of the A1g and E2g1 modes are explained in terms of the symmetries of the exciton states and the exciton-phonon coupling. Other smaller peaks including E1g and A2u2 are forbidden but appear due to the resonance effect near optical transition energies. PMID:26601614

  9. Investigating the atmospheric energy spectra using ECMWF analysis: Regional dependence

    NASA Astrophysics Data System (ADS)

    Mukherjee, P.; Zhang, M.

    2010-12-01

    The atmospheric turbulence energy spectrum has been a subject of active research for a long time. Beginning with Kolmogorov’s theory of three-dimensional turbulence, to Kraichnan’s two-dimensional turbulence and its extension to the quasi-geostrophic case by Charney, various theoretical models and hypothesis have tried to explain the energy spectrum slope. However, the success or failure of a theory can only be gauged by comparing its output with actual observational data. Nastrom and Gage were able to do just that by analyzing thousands of flight observation data and plotting the wave number spectra of wind and temperature in 1980’s. But, the flight data was confined only to the upper atmosphere and mostly mid-latitudes of northern hemisphere. We use the high-resolution ECMWF analysis data, as a part of Year of Tropical Convection (YOTC) to study the atmospheric energy spectra over a wide range of conditions. We compared and interpreted the differences of the atmospheric energy spectra in the tropics and mid-latitudes, in the winter (DJF) and summer (JJA), at the surface and in the upper troposphere. Our results conform to the previously observed -3 power law for mid-latitude data in the upper troposphere, but the slope of the energy spectrum from the surface wind data and for the tropics exhibited quite different shapes. The causes of these differences are discussed.

  10. Quintessence in a quandary: Prior dependence in dark energy models

    NASA Astrophysics Data System (ADS)

    Marsh, David J. E.; Bull, Philip; Ferreira, Pedro G.; Pontzen, Andrew

    2014-11-01

    The archetypal theory of dark energy is quintessence: a minimally coupled scalar field with a canonical kinetic energy and potential. By studying random potentials, we show that quintessence imposes a restricted set of priors on the equation of state of dark energy. Focusing on the commonly used parametrization, w (a )≈w0+wa(1 -a ) , we show that there is a natural scale and direction in the (w0,wa) plane that distinguishes quintessence as a general framework. We calculate the expected information gain for a given survey and show that, because of the nontrivial prior information, it is a function of more than just the figure of merit. This allows us to make a quantitative case for novel survey strategies. We show that the scale of the prior sets target observational requirements for gaining significant information. This corresponds to a figure of merit FOM ≳200 , a requirement that future galaxy redshift surveys will meet.

  11. Energy dependence of island nucleation density during ion beam deposition

    NASA Astrophysics Data System (ADS)

    Pomeroy, Joshua M.; Brock, Joel D.

    2002-03-01

    Thin copper films were grown on single crystal copper substrates using highly collimated copper ion beams with precisely controlled incidence energies. The energetic collisions between the copper ions and the surface can form adatom-vacancy pairs or sputter eject atoms into the vaccuum. Island nucleation densities are affected by these atomistic mechanisms, which increase surface adatom densities and surface defect densities. This paper reports STM measurements of the island nucleation density for films grown both thermally and at energies between 10-150 eV. The measured island nucleation density systematically deviates with increasing energy from the density predicted by mean field nucleation theory (J.A. Venables, et.al., Rep. Prog. Phys. 47 (1984) p. 399-459). This deviation can be understood using a phenomenological extension of mean field nucleation theory that includes the effects of adatom-vacancy pair production and sputter ejection on the effective flux.

  12. Excitation-energy dependence of the giant dipole resonance width

    NASA Astrophysics Data System (ADS)

    Enders, G.; Berg, F. D.; Hagel, K.; Kühn, W.; Metag, V.; Novotny, R.; Pfeiffer, M.; Schwalb, O.; Charity, R. J.; Gobbi, A.; Freifelder, R.; Henning, W.; Hildenbrand, K. D.; Holzmann, R.; Mayer, R. S.; Simon, R. S.; Wessels, J. P.; Casini, G.; Olmi, A.; Stefanini, A. A.

    1992-07-01

    High-energy γ rays have been measured in coincidence with heavy fragents in deeply inelastic reactions of 136Xe+48Ti at 18.5 MeV/nucleon. The giant dipole resonance (GDR) strength function is deduced from an analysis of the photon spectra within the statistical model. The GDR width Γ is studied as a function of the fragment excitation energy E*. A saturation at about Γ=10 MeV is observed for E*/A>=1.0 MeV/nucleon.

  13. Fermi energy-dependence of electromagnetic wave absorption in graphene

    NASA Astrophysics Data System (ADS)

    Shoufie Ukhtary, M.; Hasdeo, Eddwi H.; Nugraha, Ahmad R. T.; Saito, Riichiro

    2015-05-01

    Undoped graphene is known to absorb 2.3% of visible light at a normal angle of incidence. In this paper, we theoretically demonstrate that the absorption of 10-100 GHz of an electromagnetic wave can be tuned from nearly 0 to 100% by varying the Fermi energy of graphene when the angle of incidence of the electromagnetic wave is kept within total internal reflection geometry. We calculate the absorption probability of the electromagnetic wave as a function of the Fermi energy of graphene and the angle of incidence of the wave. These results open up possibilities for the development of simple electromagnetic wave-switching devices operated by gate voltage.

  14. Collision Energy Dependence of Defect Formation in Graphene

    SciTech Connect

    Mao, Fei; Zhang, Chao; Zhang, Yanwen; Zhang, Fenf-Shou

    2012-01-01

    Molecular dynamics simulations are performed using an empirical potential to simulate the collision process of an energetic carbon atom hitting a graphene sheet. According to the different impact locations within the graphene sheet, the incident threshold energies of different defects caused by the collision are determined to be 22 eV for a single vacancy, 36 eV for a divacancy, 60 eV for a Stone-Wales defect, and 65 eV for a hexavacancy. Study of the evolution and stability of the defects formed by these collisions suggests that the single vacancy reconstructs into a pentagon pair and the divacancy transforms into a pentagon-octagon-pentagon configuration. The displacement threshold energy in graphene is investigated by using the dynamical method, and a reasonable value 22.42 eV is clarified by eliminating the heating effect induced by the collision.

  15. Quasi-Periodic Oscillations: Energy Dependent Time-lags

    NASA Astrophysics Data System (ADS)

    Misra, R.; Mandal, S.

    2014-07-01

    We present a a generic model for alternating lags in QPO harmonics where variations in the photon spectrum are caused by oscillations in two parameters that characterize the spectrum. The model assumes that variations in one of the parameters are linearly driven by variations in the other after a time delay. We show that alternating lags will be observed for a range of time delays. We have further developed a phenomenological model based on this generic one that can explain the amplitude and phase lag variation with energy of the fundamental and the next three harmonics of the 67 mHz QPO observed in GRS 1915+105. The phenomenological model also predicts the variation of the Bicoherence phase with energy, which can be checked by further analysis of the observational data.

  16. Energy Dependence of SEP Electron and Proton Onset Times

    NASA Astrophysics Data System (ADS)

    Makela, P. A.; Xie, H.; Gopalswamy, N.; St Cyr, O. C.

    2015-12-01

    We study the large solar energetic particle (SEP) events that were detected by GOES in the > 10 MeV energy channel during December 2006 to March 2014. Using multi-spacecraft observations from STEREO A, B and SOHO, we are able to determine accurately the solar particle release (SPR) time of SEP electrons and protons. We first compute connection angles (CA) between the solar events and magnetic foot-points connecting to each spacecraft. By choosing the smallest CA, we derive the electron and proton SPRs using electron fluxes from the SOHO Electron Proton and Helium Instrument (EPHIN), proton fluxes from the SOHO Energetic and Relativistic Nuclei and Electron instrument (ERNE), and from the High Energy Telescope (HET) on STEREO. It is found that: 1) the 0.25 MeV-0.7 MeV electron SPRs are ~10 min earlier than 2.64 MeV - 10.4 Mev electron SPRs; 2) the proton SPRs inferred from high-energy channels (> 50 MeV) are similar to electron SPRs; 3) the proton SPRs inferred from lower energy channel (10 - 16.9 MeV) can be either ~ 7 min earlier than or delayed from the electron SPRs for tens of minutes to hours, especially for SEPs with large pre-event background flux levels. In this study, we evaluated the effects of large scattering and high background levels on SPRs and made suggested corrections for the background effect on SPR times. We also find that for some large SEP events, the observed EPHIN electron and ERNE proton intensity profiles show a double-peak feature. The onset of the first peak corresponds well to the associated Type III and metric Type II onset and tends to be nearly scattering-free.

  17. Dependence of bunch energy loss in cavities on beam velocity

    NASA Astrophysics Data System (ADS)

    Kurennoy, Sergey S.

    1999-03-01

    Beam energy loss in a cavity can be easily computed for a relativistic bunch using time-domain codes like MAFIA or ABCI. However, for nonrelativistic beams the problem is more complicated because of difficulties with its numerical formulation in the time domain. We calculate the cavity loss factors for a bunch in frequency domain as a function of its velocity and compare results with the relativistic case.

  18. Beam energy dependence of azimuthal anisotropy at RHIC-PHENIX

    SciTech Connect

    Taranenko, A.

    2012-05-15

    Recent PHENIX measurements of the elliptic ({upsilon}{sub 2}) and hexadecapole ({upsilon}{sub 4}) Fourier flow coefficients for charged hadrons as a function of transverse momentum (p{sub T}), collision centrality and particle species are presented and compared with results from the PHOBOS and STAR Collaborations respectively. The status of extensions to future PHENIX measurements at lower beam energies is also discussed.

  19. Energy and rotation-dependent stereodynamics of reaction

    NASA Astrophysics Data System (ADS)

    Yong-Qing, Li; Yun-Fan, Yang; Yang, Yu; Yong-Jia, Zhang; Feng-Cai, Ma

    2016-02-01

    Quasi-classical trajectory calculations are performed to study the stereodynamics of the reaction based on the first excited state NH2(12A‧) potential energy surface reported by Li et al. [Li Y Q and Varandas A J C 2010 J. Phys. Chem. A 114 9644] for the first time. We observe the changes of differential cross-sections at different collision energies and different initial reagent rotational excitations. The influence of collision energy on the k-k‧ distribution can be attributed to a purely impulsive effect. Initial reagent rotational excitation transforms the reaction mechanism from insertion to abstraction. The effect of initial reagent rotational excitations on k-k‧ distribution can be explained by the rotational excitation enlarging the rotational rate of reagent NH in the entrance channel to reduce the probability of collision between incidence H atom and H atom of target molecular. We also investigate the changes of vector correlations and find that the rotational angular momentum vector j‧ of the product H2 is not only aligned, but also oriented along the y axis. The alignment parameter, the disposal of total angular momentum and the reaction mechanism are all analyzed carefully to explain the polarization behavior of the product rotational angular moment. Project supported by the National Natural Science Foundation of China (Grant Nos. 11474141and 11274149), the Program for Liaoning Excellent Talents in University, China (Grant No. LJQ2015040), the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry, China (Grant No. 2014-1685), and the Special Fund Based Research New Technology of Methanol Conversion and Coal Instead of Oil and the China Postdoctoral Science Foundation (Grant No. 2014M550158).

  20. Interatomic scattering in energy dependent photoelectron spectra of Ar clusters

    SciTech Connect

    Patanen, M.; Benkoula, S.; Nicolas, C.; Goel, A.; Antonsson, E.; Neville, J. J.; Miron, C.

    2015-09-28

    Soft X-ray photoelectron spectra of Ar 2p levels of atomic argon and argon clusters are recorded over an extended range of photon energies. The Ar 2p intensity ratios between atomic argon and clusters’ surface and bulk components reveal oscillations similar to photoelectron extended X-ray absorption fine structure signal (PEXAFS). We demonstrate here that this technique allows us to analyze separately the PEXAFS signals from surface and bulk sites of free-standing, neutral clusters, revealing a bond contraction at the surface.

  1. Climate impacts of energy technologies depend on emissions timing

    NASA Astrophysics Data System (ADS)

    Edwards, Morgan R.; Trancik, Jessika E.

    2014-05-01

    Energy technologies emit greenhouse gases with differing radiative efficiencies and atmospheric lifetimes. Standard practice for evaluating technologies, which uses the global warming potential (GWP) to compare the integrated radiative forcing of emitted gases over a fixed time horizon, does not acknowledge the importance of a changing background climate relative to climate change mitigation targets. Here we demonstrate that the GWP misvalues the impact of CH4-emitting technologies as mid-century approaches, and we propose a new class of metrics to evaluate technologies based on their time of use. The instantaneous climate impact (ICI) compares gases in an expected radiative forcing stabilization year, and the cumulative climate impact (CCI) compares their time-integrated radiative forcing up to a stabilization year. Using these dynamic metrics, we quantify the climate impacts of technologies and show that high-CH4-emitting energy sources become less advantageous over time. The impact of natural gas for transportation, with CH4 leakage, exceeds that of gasoline within 1-2 decades for a commonly cited 3 W m-2 stabilization target. The impact of algae biodiesel overtakes that of corn ethanol within 2-3 decades, where algae co-products are used to produce biogas and corn co-products are used for animal feed. The proposed metrics capture the changing importance of CH4 emissions as a climate threshold is approached, thereby addressing a major shortcoming of the GWP for technology evaluation.

  2. Pole structure from energy-dependent and single-energy fits to GWU-SAID π N elastic scattering data

    NASA Astrophysics Data System (ADS)

    Švarc, Alfred; Hadžimehmedović, Mirza; Osmanović, Hedim; Stahov, Jugoslav; Workman, Ron L.

    2015-01-01

    The pole structure of the current George Washington University (GWU-SAID) partial-wave analysis of elastic π N scattering and η N production data is studied. Pole positions and residues are extracted from both the energy-dependent and single-energy fits, using two different methods. For the energy-dependent fits, both contour integration and a Laurent + Pietarinen approach are used. In the case of single-energy fits, the Laurent+Pietarinen approach is used. Errors are estimated and the two sets of results are compared to other fits to data.

  3. Energy dependence of ion-assisted chemical etch rates in reactive plasmas

    SciTech Connect

    Stafford, L.; Margot, J.; Chaker, M.; Pearton, S.J.

    2005-08-15

    In a highly cited paper, Steinbruechel [C. Steinbruechel, Appl. Phys. Lett. 55, 1960 (1989)] has demonstrated that in the sub-keV region the etch yield scales like the square root of the ion energy. Based on this result, many authors have subsequently applied this specific energy dependence to ion-assisted chemical etch rates of various materials in different etch tools. In this work, it is demonstrated that in contrast to the etch yield, the etch rate cannot universally be modeled by a simple square-root energy dependence. A novel model accounting for the correct energy dependence of ion-assisted chemical etch rates is therefore proposed. Application of this model to the etching of SiO{sub 2} and ZnO in halogenated plasma chemistries provides a quantitative description of the simultaneous dependence of the etch rate on ion energy and on ion and reactive neutral fluxes.

  4. Two time-dependent, focus-dependent experiments using the energy-dispersive spectrometer at LURE

    SciTech Connect

    Fontaine, A.; Baudelet, F.; Dartyge, E.; Guay, D. , Bat. 209d, F91405 Orsay Cedex ); Itie, J.P. , Bat. 209d, F91405 Orsay Cedex Laboratoire des Milieux Condenses Tour 14 Universite Paris VI-CNRS, F-75232 Paris ); Polian, A. ); Tolentino, H. , Bat. 209d, F91405 Orsay Cedex ); Tourillon, G. , Bat. 209d, F91405 Orsay Cedex )

    1992-01-01

    Rather than a brief review of what has been achieved at LURE (A. Fontaine, E. Dartyge, J. P. Itie, A. Polian, H. Tolentino, and G. Tourillon, {ital Topics} {ital in} {ital Current} {ital Chemistry} {bold 151}, (Springer, Berlin, 1989), Vol. 151) since 1985 with the fully dedicated, energy dispersive x-ray absorption fine structure beam line, we will present two classes of experiments plus a discussion on the present ultimate source of noise of our mechanical movement-free spectrometer. Moreover, the readers interested in this field, can find two other studies with the new born ports at Hamburg (M. Hagelstein, S. Cunis, R. Frahm, W. Niemann, and P. Rabe, Phys. B {bold 158}, 324 (1989)) and Daresbury (G. Baker, C. Richard, A. Catlow, J. Couves, A. J. Dent, G. Derbyshire, G. N. Greaves, and J. M. Thomas, XAFS VI York 1990). Related to this field are the quick extended x-ray absorption fine structure spectrometers developed initially at Hamburg under R. Frahm (R. Frahm, Nucl. Instrum. Methods A {bold 270}, 578 (1988)) and at LURE under P. Lagarde and C. Prietto (P. Lagarde, M. Lemonnier, and H. Dexpert, Physica B {bold 158}, 337 (1989)), which have been able in these two years to open new routes in a wide variety of science.

  5. Energy dependence of the trapping of uranium atoms by aluminum oxide surfaces

    NASA Technical Reports Server (NTRS)

    Librecht, K. G.

    1979-01-01

    The energy dependence of the trapping probability for sputtered U-235 atoms striking an oxidized aluminum collector surface at energies between 1 eV and 184 eV was measured. At the lowest energies, approximately 10% of the uranium atoms are not trapped, while above 10 eV essentially all of them stick. Trapping probabilities averaged over the sputtered energy distribution for uranium incident on gold and mica are also presented.

  6. Amino Acid Mean Excitation Energies and Directional Dependencies from Core and Bond Calculations

    SciTech Connect

    Sabin, John R.; Oddershede, Jens; Sauer, Stephan P. A.

    2008-12-08

    We determine the mean excitation energies of several amino acids using a Bragg Rule developed for molecular fragments or functional groups. As the composition of the amino acids is very similar, we find that the amino acids have similar mean excitation energies (approximately 70 eV). Differences arise from variation of the side chains (-R); addition of-CH2-groups decreases the mean excitation energy. We also speculate concerning the directional dependence of the amino acid mean excitation energies.

  7. Energy dependence of relativistic electron flux variations in the outer radiation belt during geomagnetic storms

    NASA Astrophysics Data System (ADS)

    Xiong, Ying; Xie, Lun; Li, Jinxing; Fu, Suiyan; Pu, Zuyin; Chen, Lunjin; Ni, Binbin; Li, Wen

    2015-04-01

    Geomagnetic storms can either increase or decrease relativistic electron fluxes in the outer radiation belt, depending on the delicate competition between electron energization and loss processes. Despite the well-known "energy independent" prototype in which electron fluxes enhance after geomagnetic storms at all energies, we present observations of "energy dependent" events, i.e., post-storm electron fluxes at lower energies (0.3-2.5 MeV, measured by MEPED/POES) recover or even exceed the pre-storm level, while electron fluxes at higher energies (2.5-14 MeV, measured by PET/SAMPEX) do not restore. The statistical survey of 84 isolated storms demonstrates that geomagnetic storms preferentially decrease relativistic electron fluxes at higher energies while flux enhancements are more common at lower energies: ~ 82% (3%) storm events produce increased (decreased) flux for 0.3-2.5 MeV electrons, while ~ 37% (45%) storms lead to enhancements (reductions) of 2.5-14 MeV electron flux. Superposed epoch analysis suggests that "energy dependent" events preferentially occur during periods of high solar wind density along with high dynamic pressure. Previous statistical studies have shown that this kind of solar wind conditions account for significant enhancements of EMIC waves, which cause efficient precipitation of > 2 MeV electrons into atmosphere via pitch angle scattering. Two cases of "energy dependent" events are investigated in detail with evident observations of EMIC waves that can resonate effectively with >2 MeV electrons. Besides, we do not capture much differences in the chorus wave activity between those "energy dependent" and "energy independent" events. Therefore, our results strongly suggest that EMIC waves play a crucial role in the occurrences of those "energy dependent" events in the outer zone during geomagnetic storms.

  8. Simple Model for Gold Nano Particles Concentration Dependence of Resonance Energy Transfer Intensity

    NASA Astrophysics Data System (ADS)

    Hoa, N. M.; Ha, C. V.; Nga, D. T.; Lan, N. T.; Nhung, T. H.; Viet, N. A.

    2016-06-01

    Gold nano particles (GNPs) concentration dependence of the energy transfer occurs between the fluorophores and GNPs is investigated. In the case of theses pairs, GNPs can enhance or quench the fluorescence of fluorophores depending upon the relative magnitudes of two energy transfer mechanisms: i) the plasmonic field enhancement at the fluorophores emission frequencies (plasmon coupled fluorescence enhancement) and ii) the localized plasmon coupled Forster energy transfer from fluorescent particles to gold particles, which quenches the fluorescence. The competition of these mechanisms is depending on the spectral overlap of fluorophores and GNPs, their relative concentration, excitation wavelength. Simple two branches surface plasmon polariton model for GNPs concentration dependence of the energy transfer is proposed. The experimental data and theoretical results confirm our findings.

  9. ENERGY-DEPENDENT TIME LAGS IN THE SEYFERT 1 GALAXY NGC 4593

    SciTech Connect

    Sriram, K.; Agrawal, V. K.; Rao, A. R.

    2009-08-01

    We investigate the energy-time lag dependence of the source NGC 4593 using XMM-Newton/EPIC pn data. We found that the time lag dependency is linear in nature with respect to the logarithm of different energy bands. We also investigate the frequency-dependent time lags and identify that at some frequency range (5 x 10{sup -5} Hz to 2 x 10{sup -4} Hz) the X-ray emission is highly coherent, mildly frequency dependent, and very strongly energy dependent. These observations can be explained in the framework of the thermal Comptonization process, and they indicate a truncated accretion disk very close to the black hole. We discuss the plausible spectral state to explain the phenomenon and conclude that the observed properties bear a close resemblance to the intermediate state or the steep power-law state, found in galactic black hole sources.

  10. Momentum and energy dependence of the anomalous high-energy dispersion in the electronic structure of high temperature superconductors.

    PubMed

    Inosov, D S; Fink, J; Kordyuk, A A; Borisenko, S V; Zabolotnyy, V B; Schuster, R; Knupfer, M; Büchner, B; Follath, R; Dürr, H A; Eberhardt, W; Hinkov, V; Keimer, B; Berger, H

    2007-12-01

    Using high-resolution angle-resolved photoemission spectroscopy we have studied the momentum and photon energy dependence of the anomalous high-energy dispersion, termed waterfalls, between the Fermi level and 1 eV binding energy in several high-T_{c} superconductors. We observe strong changes of the dispersion between different Brillouin zones and a strong dependence on the photon energy around 75 eV, which we associate with the resonant photoemission at the Cu3p-->3d_{x;{2}-y;{2}} edge. We conclude that the high-energy "waterfall" dispersion results from a strong suppression of the photoemission intensity at the center of the Brillouin zone due to matrix element effects and is, therefore, not an intrinsic feature of the spectral function. This indicates that the new high-energy scale in the electronic structure of cuprates derived from the waterfall-like dispersion may be incorrect. PMID:18233401

  11. Momentum and energy dependence of the anomalous high-energy dispersion in the electronic structure of high temperature superconductors.

    PubMed

    Inosov, D S; Fink, J; Kordyuk, A A; Borisenko, S V; Zabolotnyy, V B; Schuster, R; Knupfer, M; Büchner, B; Follath, R; Dürr, H A; Eberhardt, W; Hinkov, V; Keimer, B; Berger, H

    2007-12-01

    Using high-resolution angle-resolved photoemission spectroscopy we have studied the momentum and photon energy dependence of the anomalous high-energy dispersion, termed waterfalls, between the Fermi level and 1 eV binding energy in several high-T_{c} superconductors. We observe strong changes of the dispersion between different Brillouin zones and a strong dependence on the photon energy around 75 eV, which we associate with the resonant photoemission at the Cu3p-->3d_{x;{2}-y;{2}} edge. We conclude that the high-energy "waterfall" dispersion results from a strong suppression of the photoemission intensity at the center of the Brillouin zone due to matrix element effects and is, therefore, not an intrinsic feature of the spectral function. This indicates that the new high-energy scale in the electronic structure of cuprates derived from the waterfall-like dispersion may be incorrect.

  12. Energy dependence of the characteristic decay time of proton fluxes in solar cosmic ray events

    NASA Astrophysics Data System (ADS)

    Daibog, E. I.; Logachev, Yu. I.; Kecskemety, K.

    2008-02-01

    Energetic solar proton events within the energy interval 1-48 MeV at the stage of their decay are considered over the period of 1974-2001. The dependence of the characteristic decay time on the proton energy in the assumed power-law representation τ( E) = E - n is analyzed for the events with an exponential decay form. The dependence of n on the heliolongitude of the flare (the particles source on the Sun) is studied.

  13. Spinless relativistic particle in energy-dependent potential and normalization of the wave function

    NASA Astrophysics Data System (ADS)

    Benchikha, Amar; Chetouani, Lyazid

    2014-06-01

    The problem of normalization related to a Klein-Gordon particle subjected to vector plus scalar energy-dependent potentials is clarified in the context of the path integral approach. In addition the correction relating to the normalizing constant of wave functions is exactly determined. As examples, the energy dependent linear and Coulomb potentials are considered. The wave functions obtained via spectral decomposition, were found exactly normalized.

  14. NUCLEAR PHYSICS: Deexcitation Energy of Superdeformed Secondary Minima as a Probe to Density Dependence of Symmetry Energy

    NASA Astrophysics Data System (ADS)

    Jiang, Wei-Zhou; Lu, Xing; Chen, Yun-Peng

    2010-10-01

    Deexcitation energies of superdeformed secondary minima of odd-odd Au and Tl isotopes are investigated with the relativistic mean field (RMF) model where the isoscalar-isovector coupling is included to change the symmetry energy. It is verified by the theoretical analysis and numerical results that the deexcitation energies of superdeformed secondary minima relative to the ground states in these heavy nuclei are sensitive to differences in the symmetry energy. In particular, the linear correlation between the deexcitation energies of odd-odd Au and Tl isotopes and the neutron skin thickness in 208Pb is established. Moreover, explorations are extended to superdeformed candidates of other mass regions. It is found that the linear correlation can even be established between the deexcitation energies and the symmetry pressure at subsaturation density. These indicate that deexcitation energies can serve as a probe to the density dependence of the symmetry energy.

  15. cGMP-dependent protein kinase: linking foraging to energy homeostasis.

    PubMed

    Kaun, Karla R; Sokolowski, Marla B

    2009-01-01

    Successful foraging is necessary for procurement of nutritional resources essential for an animal's survival. Maintenance of foraging and food acquisition is dependent on the ability to balance food intake and energy expenditure. This review examines the role of cGMP-dependent protein kinase (PKG) as a regulator of foraging behaviour, food acquisition, and energy balance. The role of PKG in food-related behaviours is highly conserved among worms, flies, bees, ants, and mammals. A growing body of literature suggests that PKG plays an integral role in the component behaviours and physiologies underlying foraging behaviour. These include energy acquisition, nutrient absorption, nutrient allocation, nutrient storage, and energy use. New evidence suggests that PKG mediates both neural and physiological mechanisms underlying these processes. This review illustrates how investigating the role of PKG in energy homeostasis in a diversity of organisms can offer a broad perspective on the mechanisms mediating energy balance.

  16. Energy dependence of the probability for asymmetric fission of /sup 213/At

    SciTech Connect

    Gruzintsev, E.N.; Itkis, M.G.; Okolovich, V.N.; Rusanov, A.Y.; Smirenkin, G.N.; Tolstikov, V.N.

    1982-10-20

    The mass distribution of the fragments of the fission of /sup 213/At in the reaction /sup 209/Bi(..cap alpha.., f) has been measured for ..cap alpha.. energies in the range 34.7--50 MeV. Over the entire energy range studied, the asymmetric mode is an improbable, slightly energy-dependent mode for the /sup 213/At fission. This property of the /sup 213/At fission represents a qualitative distinction from the fission of heavy nuclei.

  17. Level-energy-dependent mean velocities of excited tungsten atoms sputtered by krypton-ion bombardment

    SciTech Connect

    Nogami, Keisuke; Sakai, Yasuhiro; Mineta, Shota; Kato, Daiji; Murakami, Izumi; Sakaue, Hiroyuki A.; Kenmotsu, Takahiro; Furuya, Kenji; Motohashi, Kenji

    2015-11-15

    Visible emission spectra were acquired from neutral atoms sputtered by 35–60 keV Kr{sup +} ions from a polycrystalline tungsten surface. Mean velocities of excited tungsten atoms in seven different 6p states were also obtained via the dependence of photon intensities on the distance from the surface. The average velocities parallel to the surface normal varied by factors of 2–4 for atoms in the different 6p energy levels. However, they were almost independent of the incident ion kinetic energy. The 6p-level energy dependence indicated that the velocities of the excited atoms were determined by inelastic processes that involve resonant charge exchange.

  18. Multireference Møller Plesset perturbation theory using spin-dependent orbital energies

    NASA Astrophysics Data System (ADS)

    Kobayashi, Yuka; Nakano, Haruyuki; Hirao, Kimihiko

    2001-03-01

    The use of spin-dependent orbital energies is proposed in the multireference Møller-Plesset perturbation theory. In this method a single canonical Fock orbital set is used for both alpha and beta electrons, while the orbital energies depend on the spin of the electron that occupies the orbital. The method is tested on the energy splitting between states of different spins in the CH 2, CF 2, CO, O 2, N 2+, and o-benzyne molecules. The results agree well with available experimental data; the deviations are within 4 kcal/mol in all cases considered.

  19. Nonlinear thermoelectric response due to energy-dependent transport properties of a quantum dot

    NASA Astrophysics Data System (ADS)

    Svilans, Artis; Burke, Adam M.; Svensson, Sofia Fahlvik; Leijnse, Martin; Linke, Heiner

    2016-08-01

    Quantum dots are useful model systems for studying quantum thermoelectric behavior because of their highly energy-dependent electron transport properties, which are tunable by electrostatic gating. As a result of this strong energy dependence, the thermoelectric response of quantum dots is expected to be nonlinear with respect to an applied thermal bias. However, until now this effect has been challenging to observe because, first, it is experimentally difficult to apply a sufficiently large thermal bias at the nanoscale and, second, it is difficult to distinguish thermal bias effects from purely temperature-dependent effects due to overall heating of a device. Here we take advantage of a novel thermal biasing technique and demonstrate a nonlinear thermoelectric response in a quantum dot which is defined in a heterostructured semiconductor nanowire. We also show that a theoretical model based on the Master equations fully explains the observed nonlinear thermoelectric response given the energy-dependent transport properties of the quantum dot.

  20. Fluctuations in energy loss and their implications for dosimetry and radiobiology

    NASA Technical Reports Server (NTRS)

    Baily, N. A.; Steigerwalt, J. E.

    1972-01-01

    Serious consideration of the physics of energy deposition indicates that a fundamental change in the interpretation of absorbed dose is required at least for considerations of effects in biological systems. In addition, theoretical approaches to radiobiology and microdosimetry seem to require statistical considerations incorporating frequency distributions of the magnitude of the event sizes within the volume of interest.

  1. Temperature-Dependent Ellipsometry Measurements of Partial Coulomb Energy in Superconducting Cuprates

    NASA Astrophysics Data System (ADS)

    Levallois, J.; Tran, M. K.; Pouliot, D.; Presura, C. N.; Greene, L. H.; Eckstein, J. N.; Uccelli, J.; Giannini, E.; Gu, G. D.; Leggett, A. J.; van der Marel, D.

    2016-07-01

    We performed an experimental study of the temperature and doping dependence of the energy-loss function of the bilayer and trilayer bismuth cuprates family. The primary aim is to obtain information on the energy stored in the Coulomb interaction between the conduction electrons, on the temperature dependence thereof, and on the change of Coulomb interaction when Cooper pairs are formed. We performed temperature-dependent ellipsometry measurements on several Bi2 Sr2 CaCu2 O8 -x single crystals: underdoped with Tc=60 , 70, and 83 K; optimally doped with Tc=91 K ; overdoped with Tc=84 , 81, 70, and 58 K; as well as optimally doped Bi2 Sr2 Ca2 Cu3 O10 +x with Tc=110 K . Our first observation is that, as the temperature drops through Tc, the loss function in the range up to 2 eV displays a change of temperature dependence as compared to the temperature dependence in the normal state. This effect at—or close to—Tc depends strongly on doping, with a sign change for weak overdoping. The size of the observed change in Coulomb energy, using an extrapolation with reasonable assumptions about its q dependence, is about the same size as the condensation energy that has been measured in these compounds. Our results therefore lend support to the notion that the Coulomb energy is an important factor for stabilizing the superconducting phase. Because of the restriction to small momentum, our observations do not exclude a possible significant contribution to the condensation energy of the Coulomb energy associated with the region of q around (π ,π ).

  2. Beam Energy and System Size Dependence of Dynamical Net Charge Fluctuations

    SciTech Connect

    STAR Coll

    2008-07-21

    We present measurements of net charge fluctuations in Au + Au collisions at {radical}s{sub NN} = 19.6, 62.4, 130, and 200 GeV, Cu + Cu collisions at {radical}s{sub NN} = 62.4, 200 GeV, and p + p collisions at {radical}s = 200 GeV using the dynamical net charge fluctuations measure {nu}{sub {+-},dyn}. We observe that the dynamical fluctuations are non-zero at all energies and exhibit a modest dependence on beam energy. A weak system size dependence is also observed. We examine the collision centrality dependence of the net charge fluctuations and find that dynamical net charge fluctuations violate 1/N{sub ch} scaling, but display approximate 1/N{sub part} scaling. We also study the azimuthal and rapidity dependence of the net charge correlation strength and observe strong dependence on the azimuthal angular range and pseudorapidity widths integrated to measure the correlation.

  3. Z-dependence of thick-target bremsstrahlung produced by monoenergetic low-energy electrons

    NASA Astrophysics Data System (ADS)

    Czarnecki, S.; Short, A.; Williams, S.

    2016-07-01

    The dependence of thick-target bremsstrahlung emitted by low-energy beams of monoenergetic electrons on the atomic number of the target material has been investigated experimentally for incident electron energies of 4.25 keV and 5.00 keV using thick aluminum, copper, silver, tungsten, and gold targets. Experimental data suggest that the intensity of the thick-target bremsstrahlung emitted is more strongly dependent on the atomic number of the target material for photons with energies that are approximately equal to the energy of the incident electrons than at lower energies, and also that the dependence of thick-target bremsstrahlung on the atomic number of the target material is stronger for incident electrons of higher energies than for incident electrons of lower energies. The results of the experiments are compared to the results of simulations performed using the PENELOPE program (which is commonly used in medical physics) and to thin-target bremsstrahlung theory, as well. Comparisons suggest that the experimental dependence of thick-target bremsstrahlung on the atomic number of the target material may be slightly stronger than the results of the PENELOPE code suggest.

  4. Energy dependence of the nucleus-nucleus potential close to the Coulomb barrier

    SciTech Connect

    Washiyama, Kouhei; Lacroix, Denis

    2008-08-15

    The nucleus-nucleus interaction potentials in heavy-ion fusion reactions are extracted from the microscopic time-dependent Hartree-Fock theory for the mass symmetric reactions {sup 16}O + {sup 16}O, {sup 40}Ca + {sup 40}Ca, and {sup 48}Ca + {sup 48}Ca and the mass asymmetric reactions {sup 16}O + {sup 40,} {sup 48}Ca, {sup 40}Ca + {sup 48}Ca, {sup 16}O + {sup 208}Pb, and {sup 40}Ca + {sup 90}Zr. When the c.m. energy is much higher than the Coulomb barrier energy, potentials deduced with the microscopic theory identify with the frozen density approximation. As the c.m. energy decreases and approaches the Coulomb barrier, potentials become energy dependent. This dependence indicates dynamical reorganization of internal degrees of freedom and leads to a reduction of the 'apparent' barrier felt by the two nuclei during fusion of the order of 2-3% compared to the frozen density case. Several examples illustrate that the potential landscape changes rapidly when the c.m. energy is in the vicinity of the Coulomb barrier energy. The energy dependence is expected to have a significant role on fusion around the Coulomb barrier.

  5. Size-dependent energy in crystal plasticity and continuum dislocation models

    PubMed Central

    Mesarovic, Sinisa Dj.; Forest, Samuel; Jaric, Jovo P.

    2015-01-01

    In the light of recent progress in coarsening the discrete dislocation mechanics, we consider two questions relevant for the development of a mesoscale, size-dependent plasticity: (i) can the phenomenological expression for size-dependent energy, as quadratic form of Nye's dislocation density tensor, be justified from the point of view of dislocation mechanics and under what conditions? (ii) how can physical or phenomenological expressions for size-dependent energy be computed from dislocation mechanics in the general case of elastically anisotropic crystal? The analysis based on material and slip system symmetries implies the negative answer to the first question. However, the coarsening method developed in response to the second question, and based on the physical interpretation of the size-dependent energy as the coarsening error in dislocation interaction energy, introduces additional symmetries. The result is that the equivalence between the phenomenological and the physical expressions is possible, but only if the multiplicity of characteristic lengths associated with different slip systems, is sacrificed. Finally, we discuss the consequences of the assumption that a single length scale governs the plasticity of a crystal, and note that the plastic dissipation at interfaces has a strong dependence on the length scale embedded in the energy expression. PMID:25792963

  6. Dependence of the energy transfer to graphene on the excitation energy

    SciTech Connect

    Mackowski, Sebastian Kamińska, Izabela

    2015-07-13

    Fluorescence studies of natural photosynthetic complexes on a graphene layer demonstrate pronounced influence of the excitation wavelength on the energy transfer efficiency to graphene. Ultraviolet light yields much faster decay of fluorescence, with average efficiencies of the energy transfer equal to 87% and 65% for excitation at 405 nm and 640 nm, respectively. This implies that focused light changes locally the properties of graphene affecting the energy transfer dynamics, in an analogous way as in the case of metallic nanostructures. Demonstrating optical control of the energy transfer is important for exploiting unique properties of graphene in photonic and sensing architectures.

  7. Energy-dependent existence of soliton in the synthesis of chemical elements

    NASA Astrophysics Data System (ADS)

    Iwata, Yoritaka

    2015-05-01

    Light chemical elements are, for instance, produced through ion collisions taking place in the core of stars, where fusion is particularly important to the synthesis of chemical elements. Meanwhile soliton provides transparency leading to the hindrance of fusion cross-section. In order to explain high fusion cross-section actually observed in low incident energies, it is necessary to discover the suppression mechanism of soliton propagation. In this paper, based on a systematic three-dimensional time-dependent density functional calculation, the existence of soliton is examined for ion collisions with some incident energies, impact parameters, and nuclear force parameter sets. As a result, solitons are suggested to exist highly depending on the energy. The suppression of soliton is consequently due to the spin-orbit force and the momentum-dependent components of the nuclear force.

  8. A coarse-grain force field for RDX: Density dependent and energy conserving

    NASA Astrophysics Data System (ADS)

    Moore, Joshua D.; Barnes, Brian C.; Izvekov, Sergei; Lísal, Martin; Sellers, Michael S.; Taylor, DeCarlos E.; Brennan, John K.

    2016-03-01

    We describe the development of a density-dependent transferable coarse-grain model of crystalline hexahydro-1,3,5-trinitro-s-triazine (RDX) that can be used with the energy conserving dissipative particle dynamics method. The model is an extension of a recently reported one-site model of RDX that was developed by using a force-matching method. The density-dependent forces in that original model are provided through an interpolation scheme that poorly conserves energy. The development of the new model presented in this work first involved a multi-objective procedure to improve the structural and thermodynamic properties of the previous model, followed by the inclusion of the density dependency via a conservative form of the force field that conserves energy. The new model accurately predicts the density, structure, pressure-volume isotherm, bulk modulus, and elastic constants of the RDX crystal at ambient pressure and exhibits transferability to a liquid phase at melt conditions.

  9. Time and energy dependence of the cosmic ray gradient in the outer heliosphere

    NASA Technical Reports Server (NTRS)

    Fillius, W.; Axford, I.; Wood, D.

    1985-01-01

    Pioneers 10 and 11, now 35 and 18 AU from the Sun, continue to extend our knowledge of the spatial dependence of cosmic ray intensities in the heliosphere. Radial gradients measured from these spacecraft by UCSD detectors which have integral energy responses above thresholds of 80 and 500 MeV/nucleon are reported. An average gradient of 2%/AU typifies the data set as a whole, but there are time and energy dependences that deviate from this value. With operating lifetimes of 13 and 12 years, respectively, for the two spacecraft, the time dependence was followed for over a solar cycle. The higher energy channel shows less modulation on all time scales. At the start of the present cycle, the gradient is lower than the average value during the last solar cycle.

  10. Measurements of the spectrum and energy dependence of X-ray transition radiation

    NASA Technical Reports Server (NTRS)

    Cherry, M. L.

    1978-01-01

    The results of experiments designed to test the theory of X-ray transition radiation and to verify the predicted dependence of the characteristic features of the radiation on the radiator dimensions are presented. The X-ray frequency spectrum produced by 5- to 9-GeV electrons over the range 4 to 30 keV was measured with a calibrated single-crystal Bragg spectrometer, and at frequencies up to 100 keV with an NaI scintillator. The interference pattern in the spectrum and the hardening of the radiation with increasing foil thickness are clearly observed. The energy dependence of the total transition-radiation intensity was studied using a radiator with large dimensions designed to yield energy-dependent signals at very high particle energies, up to E/mc-squared approximately equal to 100,000. The results are in good agreement with the theoretical predictions.

  11. Simulation of energy-dependent electron diffusion processes in the Earth's outer radiation belt

    NASA Astrophysics Data System (ADS)

    Ma, Q.; Li, W.; Thorne, R. M.; Nishimura, Y.; Zhang, X.-J.; Reeves, G. D.; Kletzing, C. A.; Kurth, W. S.; Hospodarsky, G. B.; Henderson, M. G.; Spence, H. E.; Baker, D. N.; Blake, J. B.; Fennell, J. F.; Angelopoulos, V.

    2016-05-01

    The radial and local diffusion processes induced by various plasma waves govern the highly energetic electron dynamics in the Earth's radiation belts, causing distinct characteristics in electron distributions at various energies. In this study, we present our simulation results of the energetic electron evolution during a geomagnetic storm using the University of California, Los Angeles 3-D diffusion code. Following the plasma sheet electron injections, the electrons at different energy bands detected by the Magnetic Electron Ion Spectrometer (MagEIS) and Relativistic Electron Proton Telescope (REPT) instruments on board the Van Allen Probes exhibit a rapid enhancement followed by a slow diffusive movement in differential energy fluxes, and the radial extent to which electrons can penetrate into depends on energy with closer penetration toward the Earth at lower energies than higher energies. We incorporate radial diffusion, local acceleration, and loss processes due to whistler mode wave observations to perform a 3-D diffusion simulation. Our simulation results demonstrate that chorus waves cause electron flux increase by more than 1 order of magnitude during the first 18 h, and the subsequent radial extents of the energetic electrons during the storm recovery phase are determined by the coupled radial diffusion and the pitch angle scattering by EMIC waves and plasmaspheric hiss. The radial diffusion caused by ULF waves and local plasma wave scattering are energy dependent, which lead to the observed electron flux variations with energy dependences. This study suggests that plasma wave distributions in the inner magnetosphere are crucial for the energy-dependent intrusions of several hundred keV to several MeV electrons.

  12. Energy dependence of mass, charge, isotopic, and energy distributions in neutron-induced fission of 235U and 239Pu

    NASA Astrophysics Data System (ADS)

    Pasca, H.; Andreev, A. V.; Adamian, G. G.; Antonenko, N. V.; Kim, Y.

    2016-05-01

    The mass, charge, isotopic, and kinetic-energy distributions of fission fragments are studied within an improved scission-point statistical model in the reactions 235U+n and 239Pu+n at different energies of the incident neutron. The charge and mass distributions of the electromagnetic- and neutron-induced fission of 214,218Ra, 230,232,238U are also shown. The available experimental data are well reproduced and the energy-dependencies of the observable characteristics of fission are predicted for future experiments.

  13. Fragmentation in isotopic and isobaric systems as probe of density dependence of nuclear symmetry energy

    NASA Astrophysics Data System (ADS)

    Kaur, Mandeep; Gautam, Sakshi; Puri, Rajeev K.

    2016-11-01

    We probe the density-dependent behavior of symmetry energy using the yield of various fragments in central collisions of various isotopic and isobaric colliding pairs. We calculate the yields of free nucleons, light charged particles and intermediate mass fragments in neutron-rich colliding systems as well as the ratio of relative yields of above fragments and free nucleons. Our findings reveal that the ratio of relative yield of light charged particles poses better candidate to probe the density dependence of nuclear symmetry energy.

  14. Low-energy fusion dynamics of weakly bound nuclei: A time dependent perspective

    NASA Astrophysics Data System (ADS)

    Diaz-Torres, A.; Boselli, M.

    2016-05-01

    Recent dynamical fusion models for weakly bound nuclei at low incident energies, based on a time-dependent perspective, are briefly presented. The main features of both the PLATYPUS model and a new quantum approach are highlighted. In contrast to existing timedependent quantum models, the present quantum approach separates the complete and incomplete fusion from the total fusion. Calculations performed within a toy model for 6Li + 209Bi at near-barrier energies show that converged excitation functions for total, complete and incomplete fusion can be determined with the time-dependent wavepacket dynamics.

  15. Power and uneven globalization: Coalitions and energy trade dependence in the newly independent states of Europe

    NASA Astrophysics Data System (ADS)

    Linden, Corina Herron

    2000-10-01

    The economies of the European former Soviet Union were dependent upon energy subsidies in the form of virtually free oil and natural gas imports from Russia, the loss of which implied dramatic shocks to domestic production structures, and the maintenance of which implied continued policy concessions to Russia. Yet some of these states actively pursued integration into the global economy while others sought to maintain the shelter of domestic markets and Russian energy subsidies. While the economic costs of openness and restructuring would be high in all cases in the short term, it is the political costs of openness and restructuring that determine the policy of the state. Where the high costs of restructuring are borne by a politically disenfranchised group, a consensus coalition can emerge in favor of rapid restructuring and energy reorientation. Where the benefits of the status quo accrue to a well-organized coalition closely allied with the state, a consensus coalition emerges in favor of maintenance of energy subsidies from and political relationship with Russia. Where the costs of restructuring are borne broadly or by a well-organized minority group, power oscillation and fragmentation will lead to inconsistent policy and slow progress toward energy reorientation and reform. Integrating a state-in-society approach to coalition formation within the field of international political economy, the author argues that states dominated by globalist-liberalizing-nationalist coalitions were able to implement energy trade reorientation by politically disenfranchising the ethnic minorities who populated the sector most vulnerable to energy contraction, heavy industry. These "globalizers," Estonia and Latvia, bore the high costs of restructuring industries and importing energy at world prices. Belarus, dominated by pro-Moscow-statist-leftist coalitions, sought to preserve energy subsidies through political and economic reintegration with Russia. States ruled by divided

  16. Projectile-energy dependence of H-like Ar Lyman-{alpha} emission in solids

    SciTech Connect

    Watson, R.L.; Horvat, V.; Blackadar, J.M.

    1997-03-01

    Spectra of K x rays from Ar ions (incident energy 15 MeV/u) traveling in thick solid targets of Be, C, NaF, and KCl were measured with a curved crystal spectrometer for the purpose of investigating the dependence of the H-like Ar 2p-state population fraction on projectile energy and target atomic number. Information pertaining to the energy dependence of the 2p fraction was obtained from the Doppler-shifted average energies and peak shapes associated with the Lyman-{alpha} lines. Model calculations that took into consideration the fraction of ions with one 2p electron and x-ray absorption as a function of depth in the target were performed. Generally good agreement between the experimental results and the predictions of the model were observed for all of the targets except NaF. {copyright} {ital 1997} {ital The American Physical Society}

  17. System for calibrating the energy-dependent response of an elliptical Bragg-crystal spectrometer.

    PubMed

    Marrs, R E; Brown, G V; Emig, J A; Heeter, R F

    2014-11-01

    A multipurpose spectrometer (MSPEC) with elliptical crystals is in routine use to obtain x-ray spectra from laser produced plasmas in the energy range 1.0-9.0 keV. Knowledge of the energy-dependent response of the spectrometer is required for an accurate comparison of the intensities of x-ray lines of different energy. The energy-dependent response of the MSPEC has now been derived from the spectrometer geometry and calibration information on the response of its components, including two different types of detectors. Measurements of the spectrometer response with a laboratory x-ray source are used to test the calculated response and provide information on crystal reflectivity and uniformity.

  18. Analysis of optical near-field energy transfer by stochastic model unifying architectural dependencies

    SciTech Connect

    Naruse, Makoto; Akahane, Kouichi; Yamamoto, Naokatsu; Holmström, Petter; Thylén, Lars; Huant, Serge; Ohtsu, Motoichi

    2014-04-21

    We theoretically and experimentally demonstrate energy transfer mediated by optical near-field interactions in a multi-layer InAs quantum dot (QD) structure composed of a single layer of larger dots and N layers of smaller ones. We construct a stochastic model in which optical near-field interactions that follow a Yukawa potential, QD size fluctuations, and temperature-dependent energy level broadening are unified, enabling us to examine device-architecture-dependent energy transfer efficiencies. The model results are consistent with the experiments. This study provides an insight into optical energy transfer involving inherent disorders in materials and paves the way to systematic design principles of nanophotonic devices that will allow optimized performance and the realization of designated functions.

  19. Temperature dependence of vibrational energy transfer between vibrationally excited polyatomic molecules and bath gases

    NASA Astrophysics Data System (ADS)

    Zalesskaya, G. A.; Yakovlev, D. L.; Sambor, E. G.

    2000-08-01

    Efficiency of vibrational energy transfer (VET) in vibrational quasicontinuum of triplet states was estimated from the dependence of time-resolved delayed fluorescence of benzophenone and anthraquinone on bath gas pressure. The negative temperature dependence for vibration-vibration (V-V) and positive for vibration-translation (V-T) energy transfers from benzophenone and anthraquinone to bath gases (C 2H 4, SF 6, CCl 4, C 5H 12) were obtained between 373 and 553 K. Polarizability and dipole moment of colliding molecules seem to affect the efficiency of V-V relaxation. These data reflect the dominance of long-range attractive interactions in V-V energy transfer and short-range repulsive interactions in V-T energy transfer.

  20. Effects of activation energy and activation volume on the temperature-dependent viscosity of water.

    PubMed

    Kwang-Hua, Chu Rainer

    2016-08-01

    Water transport in a leaf is vulnerable to viscosity-induced changes. Recent research has suggested that these changes may be partially due to variation at the molecular scale, e.g., regulations via aquaporins, that induce reductions in leaf hydraulic conductance. What are the quantitative as well as qualitative changes in temperature-dependent viscosity due to the role of aquaporins in tuning activation energy and activation volume? Using the transition-state approach as well as the boundary perturbation method, we investigate temperature-dependent viscosity tuned by activation energy and activation volume. To validate our approach, we compare our numerical results with previous temperature-dependent viscosity measurements. The rather good fit between our calculations and measurements confirms our present approach. We have obtained critical parameters for the temperature-dependent (shear) viscosity of water that might be relevant to the increasing and reducing of leaf hydraulic conductance. These parameters are sensitive to temperature, activation energy, and activation volume. Once the activation energy increases, the (shear) viscosity of water increases. Our results also show that as the activation volume increases (say, 10^{-23}m^{3}), the (shear) viscosity of water decreases significantly and the latter induces the enhancing of leaf hydraulic conductance. Within the room-temperature regime, a small increase in the activation energy will increase the water viscosity or reduce the leaf hydraulic conductance. Our approach and results can be applied to diverse plant or leaf attributes. PMID:27627349

  1. Effects of activation energy and activation volume on the temperature-dependent viscosity of water.

    PubMed

    Kwang-Hua, Chu Rainer

    2016-08-01

    Water transport in a leaf is vulnerable to viscosity-induced changes. Recent research has suggested that these changes may be partially due to variation at the molecular scale, e.g., regulations via aquaporins, that induce reductions in leaf hydraulic conductance. What are the quantitative as well as qualitative changes in temperature-dependent viscosity due to the role of aquaporins in tuning activation energy and activation volume? Using the transition-state approach as well as the boundary perturbation method, we investigate temperature-dependent viscosity tuned by activation energy and activation volume. To validate our approach, we compare our numerical results with previous temperature-dependent viscosity measurements. The rather good fit between our calculations and measurements confirms our present approach. We have obtained critical parameters for the temperature-dependent (shear) viscosity of water that might be relevant to the increasing and reducing of leaf hydraulic conductance. These parameters are sensitive to temperature, activation energy, and activation volume. Once the activation energy increases, the (shear) viscosity of water increases. Our results also show that as the activation volume increases (say, 10^{-23}m^{3}), the (shear) viscosity of water decreases significantly and the latter induces the enhancing of leaf hydraulic conductance. Within the room-temperature regime, a small increase in the activation energy will increase the water viscosity or reduce the leaf hydraulic conductance. Our approach and results can be applied to diverse plant or leaf attributes.

  2. Effects of activation energy and activation volume on the temperature-dependent viscosity of water

    NASA Astrophysics Data System (ADS)

    Kwang-Hua, Chu Rainer

    2016-08-01

    Water transport in a leaf is vulnerable to viscosity-induced changes. Recent research has suggested that these changes may be partially due to variation at the molecular scale, e.g., regulations via aquaporins, that induce reductions in leaf hydraulic conductance. What are the quantitative as well as qualitative changes in temperature-dependent viscosity due to the role of aquaporins in tuning activation energy and activation volume? Using the transition-state approach as well as the boundary perturbation method, we investigate temperature-dependent viscosity tuned by activation energy and activation volume. To validate our approach, we compare our numerical results with previous temperature-dependent viscosity measurements. The rather good fit between our calculations and measurements confirms our present approach. We have obtained critical parameters for the temperature-dependent (shear) viscosity of water that might be relevant to the increasing and reducing of leaf hydraulic conductance. These parameters are sensitive to temperature, activation energy, and activation volume. Once the activation energy increases, the (shear) viscosity of water increases. Our results also show that as the activation volume increases (say, 10-23m3 ), the (shear) viscosity of water decreases significantly and the latter induces the enhancing of leaf hydraulic conductance. Within the room-temperature regime, a small increase in the activation energy will increase the water viscosity or reduce the leaf hydraulic conductance. Our approach and results can be applied to diverse plant or leaf attributes.

  3. Experimental investigation of the energy and temperature dependence of beryllium self sputtering

    SciTech Connect

    Korshunov, S.N.; Guseva, M.I.; Stolijarova, V.G.

    1995-09-01

    The low-Z metal beryllium is considered as plasma facing material (PFM) for the ITER. It is expected that operation temperature range of beryllium PFM will be (670 - 1070) K. While experimental Be-sputtering data bases exist for H{sup +}, D{sup +} and He{sup +}-ions, the self-sputtering yields of Be have only been estimated by computer simulation. In this paper we report the experimental results on the energy and temperature dependence of the beryllium self-sputtering yield (S). The energy dependence of S{sup s} in the energy range (0.5 - 10.0) keV was measured at 670 K. The self-sputtering yield of Be attains its maximal value at the ion energy of 1.5 keV, being equal to 0.32 {+-} at./ion. Comparison of the experimental results and theoretical prediction shows a good agreement for energy dependence of S{sup s}. The temperature dependence of S{sup s} in the temperature range (370-1070)K was obtained for 0.9keV Be{sup +}-ions. The value of S{sup s} is not changed up to 870 K. It sharply increases at the temperatures above 870 attaining the value of 0.75 at./ion at 1070 K.

  4. Process simulator for time-dependent material and energy flow in a continuous casting system

    SciTech Connect

    Westerberg, K.W.; McClelland, M.A.

    1995-02-06

    A process simulator is developed for the material and energy flow in a continuous casting system which utilizes an electron-beam energy source. A time-dependent, one-dimensional model is used which accounts for energy transport within the ingot and transport to the surroundings by conduction, thermal radiation, and the formation of secondary electrons. Also included are the mass and energy additions associated with the poured metal. A modified finite element method is used to solve the energy equation while tracking boundaries at the pool surface and solidification zone. Model parameters are determined using results from a steady-state experiment and a more detailed two-dimensional model for fluid flow and energy transport. For a transient experiment with pouring, a comparison is made between predicted and measured heat flows.

  5. Variation in the calibrated response of LiF, Al2O3, and silicon dosimeters when used for in-phantom measurements of source photons with energies between 30 KeV AND 300 KeV.

    PubMed

    Poudel, Sashi; Currier, Blake; Medich, David C

    2015-04-01

    The MCNP5 radiation transport code was used to quantify changes in the absorbed dose conversion factor for LiF, Al2O3, and silicon-based electronic dosimeters calibrated in-air using standard techniques and summarily used to measure absorbed dose to water when placed in a water phantom. A mono-energetic photon source was modeled at energies between 30 keV and 300 keV for a point-source placed at the center of a water phantom, a point-source placed at the surface of the phantom, and for a 10-cm radial field geometry. Dosimetric calculations were obtained for water, LiF, Al2O3, and silicon at depths of 0.2 cm and 10 cm from the source. These results were achieved using the MCNP5 *FMESH photon energy-fluence tally, which was coupled with the appropriate DE/DF card for each dosimetric material studied to convert energy-fluence into the absorbed dose. The dosimeter's absorbed dose conversion factor was calculated as a ratio of the absorbed dose to water to that of the dosimeter measured at a specified phantom depth. The dosimeter's calibration value also was obtained. Based on these results, the absorbed dose conversion factor for a LiF dosimeter was found to deviate from its calibration value by up to 9%, an Al2O3 dosimeter by 43%, and a silicon dosimeter by 61%. These data therefore can be used to obtain LiF, Al2O3, and silicon dosimeter correction factors for mono-energetic and poly-energetic sources at measurement depths up to 10 cm under the irradiation geometries investigated herein.

  6. Model for radial dependence of frequency distributions for energy imparted in nanometer volumes from HZE particles

    NASA Technical Reports Server (NTRS)

    Cucinotta, F. A.; Nikjoo, H.; Goodhead, D. T.; Decillo, J. F. (Principal Investigator)

    2000-01-01

    This paper develops a deterministic model of frequency distributions for energy imparted (total energy deposition) in small volumes similar to DNA molecules from high-energy ions of interest for space radiation protection and cancer therapy. Frequency distributions for energy imparted are useful for considering radiation quality and for modeling biological damage produced by ionizing radiation. For high-energy ions, secondary electron (delta-ray) tracks originating from a primary ion track make dominant contributions to energy deposition events in small volumes. Our method uses the distribution of electrons produced about an ion's path and incorporates results from Monte Carlo simulation of electron tracks to predict frequency distributions for ions, including their dependence on radial distance. The contribution from primary ion events is treated using an impact parameter formalism of spatially restricted linear energy transfer (LET) and energy-transfer straggling. We validate our model by comparing it directly to results from Monte Carlo simulations for proton and alpha-particle tracks. We show for the first time frequency distributions of energy imparted in DNA structures by several high-energy ions such as cosmic-ray iron ions. Our comparison with results from Monte Carlo simulations at low energies indicates the accuracy of the method.

  7. Model for radial dependence of frequency distributions for energy imparted in nanometer volumes from HZE particles.

    PubMed

    Cucinotta, F A; Nikjoo, H; Goodhead, D T

    2000-04-01

    This paper develops a deterministic model of frequency distributions for energy imparted (total energy deposition) in small volumes similar to DNA molecules from high-energy ions of interest for space radiation protection and cancer therapy. Frequency distributions for energy imparted are useful for considering radiation quality and for modeling biological damage produced by ionizing radiation. For high-energy ions, secondary electron (delta-ray) tracks originating from a primary ion track make dominant contributions to energy deposition events in small volumes. Our method uses the distribution of electrons produced about an ion's path and incorporates results from Monte Carlo simulation of electron tracks to predict frequency distributions for ions, including their dependence on radial distance. The contribution from primary ion events is treated using an impact parameter formalism of spatially restricted linear energy transfer (LET) and energy-transfer straggling. We validate our model by comparing it directly to results from Monte Carlo simulations for proton and alpha-particle tracks. We show for the first time frequency distributions of energy imparted in DNA structures by several high-energy ions such as cosmic-ray iron ions. Our comparison with results from Monte Carlo simulations at low energies indicates the accuracy of the method. PMID:10761008

  8. Dynamical thresholds and quantum undulations in the energy dependence of rotationally inelastic integral cross sections

    SciTech Connect

    Schinke, R.

    1981-12-01

    We report the observation of distinct structures in the energy dependence of rotationally inelastic integral cross sections for the systems He--Na/sub 2/ and Ne--Na/sub 2/. The calculations are performed within the infinite-order-sudden and the coupled states approximation using accurate ab initio potential energy surfaces. The integral cross section for a 0..-->..j' transition typically rises steeply at low energies, reaches a maximum, and declines slowly to the high energy region showing more or less pronounced quantum undulations. The onset of the cross section is determined by dynamical constraints rather than energy conservation. All structures in the integral cross sections are explained in terms of the energy dependence of rotational rainbow features in the corresponding differential cross sections. In particular, the undulations at higher energies stem from the supernumerary rotational rainbows. In this sense they are interpreted as analogous to the glory maxima in the elastic integral cross section for scattering from isotropic potentials. The observed structures are sensitive to the anisotropy of the repulsive branch of the potential energy surface.

  9. Scaling-law for the energy dependence of anatomic power spectrum in dedicated breast CT

    SciTech Connect

    Vedantham, Srinivasan; Shi, Linxi; Glick, Stephen J.; Karellas, Andrew

    2013-01-15

    Purpose: To determine the x-ray photon energy dependence of the anatomic power spectrum of the breast when imaged with dedicated breast computed tomography (CT). Methods: A theoretical framework for scaling the empirically determined anatomic power spectrum at one x-ray photon energy to that at any given x-ray photon energy when imaged with dedicated breast CT was developed. Theory predicted that when the anatomic power spectrum is fitted with a power curve of the form k f{sup -{beta}}, where k and {beta} are fit coefficients and f is spatial frequency, the exponent {beta} would be independent of x-ray photon energy (E), and the amplitude k scales with the square of the difference in energy-dependent linear attenuation coefficients of fibroglandular and adipose tissues. Twenty mastectomy specimens based numerical phantoms that were previously imaged with a benchtop flat-panel cone-beam CT system were converted to 3D distribution of glandular weight fraction (f{sub g}) and were used to verify the theoretical findings. The 3D power spectrum was computed in terms of f{sub g} and after converting to linear attenuation coefficients at monoenergetic x-ray photon energies of 20-80 keV in 5 keV intervals. The 1D power spectra along the axes were extracted and fitted with a power curve of the form k f{sup -{beta}}. The energy dependence of k and {beta} were analyzed. Results: For the 20 mastectomy specimen based numerical phantoms used in the study, the exponent {beta} was found to be in the range of 2.34-2.42, depending on the axis of measurement. Numerical simulations agreed with the theoretical predictions that for a power-law anatomic spectrum of the form k f{sup -{beta}}, {beta} was independent of E and k(E) =k{sub 1}[{mu}{sub g}(E) -{mu}{sub a}(E)]{sup 2}, where k{sub 1} is a constant, and {mu}{sub g}(E) and {mu}{sub a}(E) represent the energy-dependent linear attenuation coefficients of fibroglandular and adipose tissues, respectively. Conclusions: Numerical

  10. Computational scheme for pH-dependent binding free energy calculation with explicit solvent.

    PubMed

    Lee, Juyong; Miller, Benjamin T; Brooks, Bernard R

    2016-01-01

    We present a computational scheme to compute the pH-dependence of binding free energy with explicit solvent. Despite the importance of pH, the effect of pH has been generally neglected in binding free energy calculations because of a lack of accurate methods to model it. To address this limitation, we use a constant-pH methodology to obtain a true ensemble of multiple protonation states of a titratable system at a given pH and analyze the ensemble using the Bennett acceptance ratio (BAR) method. The constant pH method is based on the combination of enveloping distribution sampling (EDS) with the Hamiltonian replica exchange method (HREM), which yields an accurate semi-grand canonical ensemble of a titratable system. By considering the free energy change of constraining multiple protonation states to a single state or releasing a single protonation state to multiple states, the pH dependent binding free energy profile can be obtained. We perform benchmark simulations of a host-guest system: cucurbit[7]uril (CB[7]) and benzimidazole (BZ). BZ experiences a large pKa shift upon complex formation. The pH-dependent binding free energy profiles of the benchmark system are obtained with three different long-range interaction calculation schemes: a cutoff, the particle mesh Ewald (PME), and the isotropic periodic sum (IPS) method. Our scheme captures the pH-dependent behavior of binding free energy successfully. Absolute binding free energy values obtained with the PME and IPS methods are consistent, while cutoff method results are off by 2 kcal mol(-1) . We also discuss the characteristics of three long-range interaction calculation methods for constant-pH simulations.

  11. Charge deposition dependence and energy loss of electrons transmitted through insulating PET nanocapillaries

    NASA Astrophysics Data System (ADS)

    Keerthisinghe, D.; Dassanayake, B. S.; Wickramarachchi, S. J.; Stolterfoht, N.; Tanis, J. A.

    2013-12-01

    The charge deposition dependence and energy loss in the transmission of electrons through insulating polyethylene terephthalate (PET) were studied for incident energies of 500 and 800 eV. Charge evolution at the sample tilt angles ψ = 0.0° and -1.7° was investigated. After an initial quiescent period transmission was observed and found to reach equilibrium rather quickly. Inelastic behavior of the transmitted electrons was observed during the initial transmission as well as after reaching equilibrium for ψ = -1.7° for both incident energies.

  12. Synergy of inelastic and elastic energy loss. Temperature effects and electronic stopping power dependence

    SciTech Connect

    Zarkadoula, Eva; Xue, Haizhou; Zhang, Yanwen; Weber, William J.

    2015-06-16

    A combination of an inelastic thermal spike model suitable for insulators and molecular dynamics simulations is used to study the effects of temperature and electronic energy loss on ion track formation, size and morphology in SrTiO3 systems with pre-existing disorder. We find temperature dependence of the ion track size. In addition, we find a threshold in the electronic energy loss for a given pre-existing defect concentration, which indicates a threshold in the synergy between the inelastic and elastic energy loss.

  13. Synergy of inelastic and elastic energy loss. Temperature effects and electronic stopping power dependence

    DOE PAGES

    Zarkadoula, Eva; Xue, Haizhou; Zhang, Yanwen; Weber, William J.

    2015-06-16

    A combination of an inelastic thermal spike model suitable for insulators and molecular dynamics simulations is used to study the effects of temperature and electronic energy loss on ion track formation, size and morphology in SrTiO3 systems with pre-existing disorder. We find temperature dependence of the ion track size. In addition, we find a threshold in the electronic energy loss for a given pre-existing defect concentration, which indicates a threshold in the synergy between the inelastic and elastic energy loss.

  14. AdS/CFT energy loss in time-dependent string configurations

    NASA Astrophysics Data System (ADS)

    Ficnar, Andrej

    2012-08-01

    We analyze spacetime momentum currents on a classical string world sheet, study their generic connection via AdS/CFT correspondence to the instantaneous energy loss of the dual field theory degrees of freedom and suggest a general formula for computing energy loss in a time-dependent string configuration. Applying this formula to the case of falling strings, generally dual to light quarks, reveals that the energy loss does not display a well-pronounced Bragg peak at late times, as previously believed. Finally, we comment on the possible implications of this result to the jet quenching phenomena in heavy ion collisions.

  15. Diameter-dependent dissipation of vibration energy of cantilevered multiwall carbon nanotubes

    NASA Astrophysics Data System (ADS)

    Sawaya, Shintaro; Arie, Takayuki; Akita, Seiji

    2011-04-01

    This study investigated the mechanical properties of vibrating cantilevered multiwall carbon nanotubes in terms of energy loss in a vibrating nanotube. Young's moduli of the nanotubes show a clear dependence of the perfection of the sp2 carbon network, as determined from Raman spectroscopy. The energy loss corresponding to the inverse of the quality factor increases with increasing tube diameter, although the nanotube maintains high mechanical strength around 0.5 TPa. This fact implies that the vibration energy is dissipated mainly not by defects, but by van der Waals interactions between walls.

  16. Continuous Energy, Multi-Dimensional Transport Calculations for Problem Dependent Resonance Self-Shielding

    SciTech Connect

    T. Downar

    2009-03-31

    The overall objective of the work here has been to eliminate the approximations used in current resonance treatments by developing continuous energy multi-dimensional transport calculations for problem dependent self-shielding calculations. The work here builds on the existing resonance treatment capabilities in the ORNL SCALE code system.

  17. Density dependence of the symmetry energy from neutron skin thickness in finite nuclei

    SciTech Connect

    Vinas, X.; Centelles, M.; Roca-Maza, X.; Warda, M.

    2012-10-20

    The density dependence of the symmetry energy, characterized by the parameter L, is studied using information provided by the neutron skin thickness in finite nuclei. An estimate of L is obtained from experimental data of antiprotonic atoms. We also discuss the ability of parity violating electron scatering to obtain information about the neutron skin thickness in {sup 208}Pb.

  18. A Simple Method to Calculate the Temperature Dependence of the Gibbs Energy and Chemical Equilibrium Constants

    ERIC Educational Resources Information Center

    Vargas, Francisco M.

    2014-01-01

    The temperature dependence of the Gibbs energy and important quantities such as Henry's law constants, activity coefficients, and chemical equilibrium constants is usually calculated by using the Gibbs-Helmholtz equation. Although, this is a well-known approach and traditionally covered as part of any physical chemistry course, the required…

  19. U.S. oil dependence 2014: Is energy independence in sight?

    SciTech Connect

    Greene, David L.; Liu, Changzheng

    2015-06-10

    The importance of reducing U.S. oil dependence may have changed in light of developments in the world oil market over the past two decades. Since 2005, increased domestic production and decreased oil use have cut U.S. import dependence in half. The direct costs of oil dependence to the U.S. economy are estimated under four U.S. Energy Information Administration Scenarios to 2040. The key premises of the analysis are that the primary oil market failure is the use of market power by OPEC and that U.S. economic vulnerability is a result of the quantity of oil consumed, the lack of readily available, economical substitutes and the quantity of oil imported. Monte Carlo simulations of future oil market conditions indicate that the costs of U.S. oil dependence are likely to increase in constant dollars but decrease relative to U.S. gross domestic product unless oil resources are larger than estimated by the U.S. Energy Information Administration. In conclusion, reducing oil dependence therefore remains a valuable goal for U.S. energy policy and an important co-benefit of mitigating greenhouse gas emissions.

  20. U.S. oil dependence 2014: Is energy independence in sight?

    DOE PAGES

    Greene, David L.; Liu, Changzheng

    2015-06-10

    The importance of reducing U.S. oil dependence may have changed in light of developments in the world oil market over the past two decades. Since 2005, increased domestic production and decreased oil use have cut U.S. import dependence in half. The direct costs of oil dependence to the U.S. economy are estimated under four U.S. Energy Information Administration Scenarios to 2040. The key premises of the analysis are that the primary oil market failure is the use of market power by OPEC and that U.S. economic vulnerability is a result of the quantity of oil consumed, the lack of readilymore » available, economical substitutes and the quantity of oil imported. Monte Carlo simulations of future oil market conditions indicate that the costs of U.S. oil dependence are likely to increase in constant dollars but decrease relative to U.S. gross domestic product unless oil resources are larger than estimated by the U.S. Energy Information Administration. In conclusion, reducing oil dependence therefore remains a valuable goal for U.S. energy policy and an important co-benefit of mitigating greenhouse gas emissions.« less

  1. Space-time dependence between energy sources and climate related energy production

    NASA Astrophysics Data System (ADS)

    Engeland, Kolbjorn; Borga, Marco; Creutin, Jean-Dominique; Ramos, Maria-Helena; Tøfte, Lena; Warland, Geir

    2014-05-01

    The European Renewable Energy Directive adopted in 2009 focuses on achieving a 20% share of renewable energy in the EU overall energy mix by 2020. A major part of renewable energy production is related to climate, called "climate related energy" (CRE) production. CRE production systems (wind, solar, and hydropower) are characterized by a large degree of intermittency and variability on both short and long time scales due to the natural variability of climate variables. The main strategies to handle the variability of CRE production include energy-storage, -transport, -diversity and -information (smart grids). The three first strategies aim to smooth out the intermittency and variability of CRE production in time and space whereas the last strategy aims to provide a more optimal interaction between energy production and demand, i.e. to smooth out the residual load (the difference between demand and production). In order to increase the CRE share in the electricity system, it is essential to understand the space-time co-variability between the weather variables and CRE production under both current and future climates. This study presents a review of the literature that searches to tackle these problems. It reveals that the majority of studies deals with either a single CRE source or with the combination of two CREs, mostly wind and solar. This may be due to the fact that the most advanced countries in terms of wind equipment have also very little hydropower potential (Denmark, Ireland or UK, for instance). Hydropower is characterized by both a large storage capacity and flexibility in electricity production, and has therefore a large potential for both balancing and storing energy from wind- and solar-power. Several studies look at how to better connect regions with large share of hydropower (e.g., Scandinavia and the Alps) to regions with high shares of wind- and solar-power (e.g., green battery North-Sea net). Considering time scales, various studies consider wind

  2. The angular dependence of an Si energy deposition spectrometer response at several radiation sources.

    PubMed

    Spurný, Frantisek; Trompier, François; Bottollier-Depois, Jean-François

    2005-06-01

    An MDU-Liulin spectrometer based on an Si-diode was mainly used during the last few years with the goal to use them for measurements onboard aircraft. To investigate its ability to obtain such measurements, the detector was tested in some radiation reference fields, like 60Co and other photon beams, neutrons of an AmBe and 252Cf sources and in high-energy radiation fields at CERN. Due to the high geometrical asymmetry of the Si-diode semiconductor, an angular dependence of the response would be expected. This work presents analyses and discusses the results of angular dependence studies obtained at the different radiation sources mentioned. It was found that these angular dependences vary with the type and energy of radiation. The influence of these variations on the use as a dosimeter onboard aircraft is also studied and discussed.

  3. Dependence of Decamethylcyclopentasiloxane (DMCPS) Dissociation on Ionized Energy by Using Quadrupole Mass Spectrum

    NASA Astrophysics Data System (ADS)

    Zhang, Haiyan; Ye, Chao; Ning, Zhaoyuan

    2010-12-01

    Dependence of decamethylcyclopentasiloxane (DMCPS) organosilicon dissociation on ionized energy in the energy range of 25 eV to 70 eV is investigated by using a quadrupole mass spectrometry At the ionized energy below 55 eV, the dissociation of DMCPS is dominant. As the ionized energy is above 55 eV, the DMCPS dissociation achieves the maximum cross section, while the fragments from the DMCPS dissociation can further dissociate, which leads to a different ingredient of fragments. At the lower ionized energy of 25 eV, the main fragments are SiOC2H5+, SiCH+, Si+, O2+ and CH3+ ions, which shows an important effect on the SiCOH low-k film deposition.

  4. Monte Carlo Computational Modeling of the Energy Dependence of Atomic Oxygen Undercutting of Protected Polymers

    NASA Technical Reports Server (NTRS)

    Banks, Bruce A.; Stueber, Thomas J.; Norris, Mary Jo

    1998-01-01

    A Monte Carlo computational model has been developed which simulates atomic oxygen attack of protected polymers at defect sites in the protective coatings. The parameters defining how atomic oxygen interacts with polymers and protective coatings as well as the scattering processes which occur have been optimized to replicate experimental results observed from protected polyimide Kapton on the Long Duration Exposure Facility (LDEF) mission. Computational prediction of atomic oxygen undercutting at defect sites in protective coatings for various arrival energies was investigated. The atomic oxygen undercutting energy dependence predictions enable one to predict mass loss that would occur in low Earth orbit, based on lower energy ground laboratory atomic oxygen beam systems. Results of computational model prediction of undercut cavity size as a function of energy and defect size will be presented to provide insight into expected in-space mass loss of protected polymers with protective coating defects based on lower energy ground laboratory testing.

  5. Energy Dependent Responses of Relativistic Electron Fluxes in the Outer Radiation Belt to Geomagnetic Storms

    NASA Astrophysics Data System (ADS)

    Xie, L.

    2015-12-01

    Geomagnetic storms can either increase 4 or decrease relativistic electron fluxes in the outer radiation belt. A statistical survey of 84 isolated storms demonstrates that geomagnetic storms preferentially decrease relativistic electron fluxes at higher energies while flux enhancements are more common at lower energies. In about 87% of the storms, 0.3-2.5 MeV electrons fluxes show increase, whereas 2.5-14 MeV electron fluxes increase in only 35% of the storms. Superposed epoch analyses suggest that such 'energy dependent' behavior of electrons preferably occurs during conditions of high solar wind density which is favorable to generate magnetospheric electromagnetic ion cyclotron (EMIC) waves and these 'energy dependent' events are associated with relatively weaker chorus activities. We have examined one of the cases where observed EMIC waves can resonate effectively with >2.5 MeV electrons and scatter them into the atmosphere. The correlation study further illustrates that electron flux drop-outs during storm main phases do not correlate well with the flux build-up during storm recovery phases. We suggest that a combination of efficient EMIC-induced scattering and weaker chorus-driven acceleration provide a viable candidate for the energy dependent responses of outer radiation belt relativistic electrons to geomagnetic storms. These results are of great interest to both understanding of the radiation belt dynamics and applications in space weather.

  6. Field-dependent molecular ionization and excitation energies: Implications for electrically insulating liquids

    NASA Astrophysics Data System (ADS)

    Davari, N.; Åstrand, P.-O.; Unge, M.; Lundgaard, L. E.; Linhjell, D.

    2014-03-01

    The molecular ionization potential has a relatively strong electric-field dependence as compared to the excitation energies which has implications for electrical insulation since the excited states work as an energy sink emitting light in the UV/VIS region. At some threshold field, all the excited states of the molecule have vanished and the molecule is a two-state system with the ground state and the ionized state, which has been hypothesized as a possible origin of different streamer propagation modes. Constrained density-functional theory is used to calculate the field-dependent ionization potential of different types of molecules relevant for electrically insulating liquids. The low singlet-singlet excitation energies of each molecule have also been calculated using time-dependent density functional theory. It is shown that low-energy singlet-singlet excitation of the type n → π* (lone pair to unoccupied π* orbital) has the ability to survive at higher fields. This type of excitation can for example be found in esters, diketones and many color dyes. For alkanes (as for example n-tridecane and cyclohexane) on the other hand, all the excited states, in particular the σ → σ* excitations vanish in electric fields higher than 10 MV/cm. Further implications for the design of electrically insulating dielectric liquids based on the molecular ionization potential and excitation energies are discussed.

  7. Artificial neural network prediction model for geosynchronous electron fluxes: Dependence on satellite position and particle energy

    NASA Astrophysics Data System (ADS)

    Shin, Dae-Kyu; Lee, Dae-Young; Kim, Kyung-Chan; Hwang, Junga; Kim, Jaehun

    2016-04-01

    Geosynchronous satellites are often exposed to energetic electrons, the flux of which varies often to a large extent. Since the electrons can cause irreparable damage to the satellites, efforts to develop electron flux prediction models have long been made until recently. In this study, we adopt a neural network scheme to construct a prediction model for the geosynchronous electron flux in a wide energy range (40 keV to >2 MeV) and at a high time resolution (as based on 5 min resolution data). As the model inputs, we take the solar wind variables, geomagnetic indices, and geosynchronous electron fluxes themselves. We also take into account the magnetic local time (MLT) dependence of the geosynchronous electron fluxes. We use the electron data from two geosynchronous satellites, GOES 13 and 15, and apply the same neural network scheme separately to each of the GOES satellite data. We focus on the dependence of prediction capability on satellite's magnetic latitude and MLT as well as particle energy. Our model prediction works less efficiently for magnetic latitudes more away from the equator (thus for GOES 13 than for GOES 15) and for MLTs nearer to midnight than noon. The magnetic latitude dependence is most significant for an intermediate energy range (a few hundreds of keV), and the MLT dependence is largest for the lowest energy (40 keV). We interpret this based on degree of variance in the electron fluxes, which depends on magnetic latitude and MLT at geosynchronous orbit as well as particle energy. We demonstrate how substorms affect the flux variance.

  8. Transmission of electrons through insulating PET foils: Dependence on charge deposition, tilt angle and incident energy

    NASA Astrophysics Data System (ADS)

    Keerthisinghe, D.; Dassanayake, B. S.; Wickramarachchi, S. J.; Stolterfoht, N.; Tanis, J. A.

    2016-09-01

    Transmission of electrons through insulating polyethylene terephthalate (PET) nanocapillaries was observed as a function of charge deposition, angular and energy dependence. Two samples with capillary diameters 100 and 200 nm and pore densities 5 × 108/cm2 and 5 × 107/cm2, respectively, were studied for incident electron energies of 300, 500 and 800 eV. Transmission and steady state of the electrons were attained after a time delay during which only a few electron counts were observed. The transmission through the capillaries depended on the tilt angle with both elastic and inelastic electrons going through. The guiding ability of electrons was found to increase with the incident energy in contrast to previous measurements in our laboratory for a similar PET foil.

  9. Incident Energy Dependence of pt Correlations at RHIC

    SciTech Connect

    Adams, J.; Aggarwal, M. M.; Ahammed, Z.; Amonett, J.; Anderson, B. D.; Arkhipkin, D.; Averichev, G. S.; Badyal, S. K.; Bai, Y.; Balewski, J.; Barannikova, O.; Barnby, L. S.; Baudot, J.; Bekele, S.; Belaga, V. V.; Bellwied, R.; Berger, J.; Bezverkhny, B. I; Bharadwaj, S.; Bhasin, A.; Bhati, A. K.; Bhatia, V. S.; Bichsel, H.; Billmeier, A.; Bland, L. C.; Blyth, C. O.; Bonner, B. E.; Botje, M.; Boucham, A.; Brandin, A. V.; Bravar, A.; Bystersky, M.; Cadman, R. V.; Cai, X. Z.; Caines, H.; Castillo, J.; Cebra, D.; Chajecki, Z.; Chaloupka, P.; Chattopadhyay, S.; Chen, H. F.; Chen, Y.; Cheng, J.; Cherney, M.; Chikanian, A.; Christie, W.; Coffin, J. P.; Cormier, T. M.; Cramer, J. G.; Crawford, H. J.; Das, D.; Das, S.; de Moura, M. M.; Derevschikov, A. A.; Didenko, L.; Dietel, T.; Dogra, S. M.; Dong, W. J.; Dong, X.; Draper, J. E.; Du, F.; Dubey, A. K.; Dunin, V. B.; Dunlop, J. C.; Dutta Mazumdar, M. R.; Eckardt, V.; Edwards, W. R.; Efimov, L. G.; Emelianov, V.; Engelage, J.; Eppley, G.; Erazmus, B.; Estienne, M.; Fachini, P.; Faivre, J.; Fatemi, R.; Fedorisin, J.; Filimonov, K.; Filip, P.; Finch, E.; Fine, V.; Fisyak, Y.; Fomenko, K.; Fu, J.; Gagliardi, C. A.; Gaillard, L.; Gans, J.; Ganti, M. S.; Gaudichet, L.; Geurts, F.; Ghazikhanian, V.; Ghosh, P.; Gonzalez, J. E.; Grachov, O.; Grebenyuk, O.; Grosnick, D.; Guertin, S. M.; Guo, Y.; Gupta, A.; Gutierrez, T. D.; Hallman, T. J.; Hamed, A.; Hardtke, D.; Harris, J. W.; Heinz, M.; Henry, T. W.; Hepplemann, S.; Hippolyte, B.; Hirsch, A.; Hjort, E.; Hoffmann, G. W.; Huang, H. Z.; Huang, S. L.; Hughes, E. W.; Humanic, T. J.; Igo, G.; Ishihara, A.; Jacobs, P.; Jacobs, W. W.; Janik, M.; Jiang, H.; Jones, P. G.; Judd, E. G.; Kabana, S.; Kang, K.; Kaplan, M.; Keane, D.; Khodyrev, V. Yu; Kiryluk, J.; Kisiel, A.; Kislov, E. M.; Klay, J.; Klein, S. R.; Koetke, D. D.; Kollegger, T.; Kopytine, M.; Kotchenda, L.; Kramer, M.; Kravtsov, P.; Kravtsov, V. I.; Krueger, K.; Kuhn, C.; Kulikov, A. I.; Kumar, A.; Kutuev, R. Kh

    2005-10-01

    We present results for two-particle transverse momentum correlations, Δpt,iΔt,j, as a function of event centrality for Au+Au collisions at √(sNN) = 20, 62, 130, and 200 GeV at the Relativistic Heavy Ion Collider. We observe correlations decreasing with centrality that are similar at all four incident energies. The correlations multiplied by the multiplicity density increase with incident energy and the centrality dependence may show evidence of processes such as thermalization, jet production, or the saturation of transverse flow. The square root of the correlations divided by the event-wise average transverse momentum per event shows little or no beam energy dependence and generally agrees with previous measurements at the Super Proton Synchrotron.

  10. Fully energy-dependent HZETRN (a galactic cosmic-ray transport code)

    NASA Technical Reports Server (NTRS)

    Shinn, Judy L.; John, Sarah; Tripathi, Ram K.; Norbury, John W.; Wilson, John W.; Townsend, Lawrence W.

    1992-01-01

    For extended manned space missions, the radiation shielding design requires efficient and accurate cosmic-ray transport codes that can handle the physics processes in detail. The Langley Research Center galactic cosmic-ray transport code (HZETRN) is currently under development for such design use. The cross sections for the production of secondary nucleons in the existing HZETRN code are energy dependent only for nucleon collisions. The approximation of energy-independent, heavy-ion fragmentation cross section is now removed by implementing a mathematically simplified energy-dependent stepping formalism for heavy ions. The cross section at each computational grid is obtained by linear interpolation from a few tabulated data to minimize computing time. Test runs were made for galactic cosmic-ray transport through a liquid hydrogen shield and a water shield at solar minimum. The results show no appreciable change in total fluxes or computing time compared with energy-independent calculations. Differences in high LET (linear energy transfer) spectra are noted, however, because of the large variation in cross sections at the low-energy region. The high LET components are significantly higher in the new code and have important implications on biological risk estimates for heavy-ion exposure.

  11. Inversion of the broken ray transform in the case of energy-dependent attenuation.

    PubMed

    Krylov, R; Katsevich, A

    2015-06-01

    Broken Ray transform (BRT) arises when one considers a narrow x-ray beam propagating through medium under the assumption of single scattering. Previous algorithms for inverting the BRT assumed that the medium is characterized by a single attenuation coefficient μ. However x-rays lose their energy after Compton scattering and the energy loss depends on the scattering angle. Since the attenuation coefficient depends on energy, the μ's before and after scattering are different. When there are three or more detectors one should distinguish not only between μ's that are 'seen' by x-rays before and after scattering, but also between μ's that are 'seen' by x-rays traveling towards different detectors.The main thrust of this paper is inversion of the BRT with N ⩾ 3 detectors under the assumption that the attenuation coefficient can be accurately approximated by a linear function of energy within the window of relevant energies. When the number of detectors is four or greater, we derive a family of inversion formulas. If N > 4, we find the optimal formula, which provides the best stability with respect to noise in the data. If N = 4, the family collapses into a single formula and no optimization is possible. If μ is independent of energy, N = 3 is sufficient for inversion. We also develop iterative reconstruction algorithms that can use global and local data. The results of testing the algorithms are presented. PMID:25974246

  12. Simulations of the temperature dependence of energy transfer in the PSI core antenna.

    PubMed Central

    Jia, Y; Jean, J M; Werst, M M; Chan, C K; Fleming, G R

    1992-01-01

    In order to understand the organization of the PSI core antenna and to interpret results obtained from studies of the temperature and wavelength dependence of energy transfer and trapping in the PSI particles, we have constructed a model for PSI in which spectral heterogeneity is considered via a self-consistent approach based on Forster transport. The temperature dependence of the absorption and emission spectra of the individual Chl molecules in the protein matrix is calculated based on a model Hamiltonian which includes a phonon contribution. Time and wavelength resolved kinetics of PSI at different temperatures are investigated by means of two-dimensional lattice models. We conclude that wavelength-dependent fluorescence decay kinetics result only when two or more bottlenecks exist in the energy transfer and trapping process. A single trap or several pseudo-traps with spectrally identical environments do not lead to wavelength dependent decays. Simple funnel arrangements of the spectral types can be ruled out. At least one pigment with energy lower than the photochemical trap located close to the reaction center is required to produce the trends of the fluorescence lifetimes observed experimentally. The remainder of the core antenna is consistent with a random arrangement of spectral types. PMID:1420871

  13. Spatial dependence of high energy electrons and their radiations in pulsar wind nebulae

    NASA Astrophysics Data System (ADS)

    Lu, Fang-Wu; Gao, Quan-Gui; Zhang, Li

    2016-06-01

    We investigate the spatial dependence of high energy electrons and their radiations in pulsar wind nebulae (PWNe). By assuming a time-dependent broken power-law injection and spatial dependence of convection velocity, magnetic field strength and diffusion coefficient on the radial distance of an expanding system, we numerically solve the Fokker-Planck transport equation including convection, diffusion, adiabatic loss and radiative loss in spherical coordinates, and investigate the effects of magnetic field, PWN age, maximum energy of electrons, and diffusion coefficient on electron spectra and non-thermal photon emissions. Our results indicate that (1) electron spectra and the corresponding photon spectra are a function of radial distance r of the expanding system; (2) for a given expansion velocity, the increase of the PWN age causes a slower decrease of the convection velocity (V ∝ r -β) and a more rapid decrease of the magnetic field strength (B ∝ r -1+β), but a more rapid increase of the diffusion coefficient (κ ∝ r 1-β) because the index β decreases with the PWN age; and (3) the lower energy part of the electron spectra is dominated by convection and adiabatic loss, but the higher energy part is dominated by the competition between synchrotron loss and diffusion, and such a competition is a function of radial distance. Therefore the diffusion effect has an important role in the evolution of electron spectra as well as non-thermal photon spectra in a PWN.

  14. Spatial dependence of high energy electrons and their radiations in pulsar wind nebulae

    NASA Astrophysics Data System (ADS)

    Lu, Fang-Wu; Gao, Quan-Gui; Zhang, Li

    2016-06-01

    We investigate the spatial dependence of high energy electrons and their radiations in pulsar wind nebulae (PWNe). By assuming a time-dependent broken power-law injection and spatial dependence of convection velocity, magnetic field strength and diffusion coefficient on the radial distance of an expanding system, we numerically solve the Fokker-Planck transport equation including convection, diffusion, adiabatic loss and radiative loss in spherical coordinates, and investigate the effects of magnetic field, PWN age, maximum energy of electrons, and diffusion coefficient on electron spectra and non-thermal photon emissions. Our results indicate that (1) electron spectra and the corresponding photon spectra are a function of radial distance r of the expanding system; (2) for a given expansion velocity, the increase of the PWN age causes a slower decrease of the convection velocity (V ∝ r ‑β) and a more rapid decrease of the magnetic field strength (B ∝ r ‑1+β), but a more rapid increase of the diffusion coefficient (κ ∝ r 1‑β) because the index β decreases with the PWN age; and (3) the lower energy part of the electron spectra is dominated by convection and adiabatic loss, but the higher energy part is dominated by the competition between synchrotron loss and diffusion, and such a competition is a function of radial distance. Therefore the diffusion effect has an important role in the evolution of electron spectra as well as non-thermal photon spectra in a PWN.

  15. Beam-energy and system-size dependence of dynamical net charge fluctuations.

    SciTech Connect

    Abelev, B. I.; Aggarwal, M. M.; Ahammed, Z.; Anderson, B. D.; Arkhipkin, D.; Krueger, K.; Spinka, H. M.; Underwood, D. G.; High Energy Physics; Univ. of IIlinois; Panjab Univ.; Variable Energy Cyclotron Centre; Kent State Univ.; Particle Physic Lab.; STAR Collaboration

    2009-01-01

    We present measurements of net charge fluctuations in Au+Au collisions at {radical}s{sub NN} = 19.6, 62.4, 130, and 200 GeV, Cu+Cu collisions at {radical}s{sub NN} = 62.4 and 200 GeV, and p+p collisions at {radical}s = 200 GeV using the dynamical net charge fluctuations measure {nu}{sub +-,dyn}. We observe that the dynamical fluctuations are nonzero at all energies and exhibit a modest dependence on beam energy. A weak system size dependence is also observed. We examine the collision centrality dependence of the net charge fluctuations and find that dynamical net charge fluctuations violate 1/N{sub ch} scaling but display approximate 1/N{sub part} scaling. We also study the azimuthal and rapidity dependence of the net charge correlation strength and observe strong dependence on the azimuthal angular range and pseudorapidity widths integrated to measure the correlation.

  16. Combined alcohol and energy drink use: hedonistic motives, adenosine, and alcohol dependence.

    PubMed

    Marczinski, Cecile A

    2014-07-01

    Consumption of alcohol mixed with energy drinks (AmED) has been associated with both short- and long-term risks beyond those observed with alcohol alone. AmED use has been associated with heavy episodic (binge) drinking, risky behaviors, and risk of alcohol dependence. Laboratory research has demonstrated that AmED beverages lead to greater motivation to drink versus the same amount of alcohol consumed alone. However, the reason consumers find AmED beverages particularly appealing has been unclear. A recent report by Droste and colleagues (Alcohol Clin Exp Res 2014; 38:2087-2095) is the first study to investigate motivations related to AmED consumption and to determine which motives predict AmED consumption patterns, experience of drinking-related harms, and risk of alcohol dependence. The findings of this study significantly enhance our understanding of why AmED consumption is related to the risk of alcohol dependence and change our understanding of why consumers choose AmED beverages. The authors report that hedonistic motives strongly predicted AmED use and the harms associated with use. While intoxication-reduction motives predicted self-reported accidents and injuries, these motives did not predict AmED consumption patterns and risk of dependence. The risk of alcohol dependence may arise from repeated experiences when drinking alcohol is more pleasurable when energy drinks are consumed with the alcohol. This commentary will focus on why energy drinks might increase the rewarding properties of alcohol in social drinkers. In addition, discussion is provided explaining why more research on the neurotransmitter, adenosine, may actually inform us about the mechanisms contributing to the development of alcohol dependence. PMID:25040590

  17. Latitudinal and Energy Dependence of Energetic Neutral Atom Spectral Indices Measured by the Interstellar Boundary Explorer

    NASA Astrophysics Data System (ADS)

    Desai, M. I.; Allegrini, F.; Dayeh, M. A.; Funsten, H.; Heerikhuisen, J.; McComas, D. J.; Fuselier, S. A.; Pogorelov, N.; Schwadron, N. A.; Zank, G. P.; Zirnstein, E. J.

    2015-04-01

    We investigate the latitudinal and energy dependence of the globally distributed 0.5-6 keV energetic neutral atom (ENA) spectra measured by the Interstellar Boundary Explorer (IBEX) during the first 3 yrs of the mission. Our results are: (1) the ENA spectral indices at the two lowest energies (0.89 and 1.47 keV) exhibit no clear trend with ecliptic latitude θ, while those at ˜2.29 and ˜3.41 keV exhibit a clear latitudinal pattern; flatter spectra occur above 60° latitude and steeper spectra occur ±30° of the equator. (2) The latitudinal dependence of the spectral indices at different energies can be represented by the cosine function γ ={{a}0}+{{a}1}cos ({{a}2}θ ) with unique offsets, amplitudes, and phase angles; the higher energy ENA indices transition to successively larger amplitudes within ±45° of the equator. Our results confirm the previously reported latitudinal organization of the ENA spectra and their remarkable similarity to that of the solar wind (SW) speed observed by Ulysses in the inner heliosphere. While earlier studies showed that the ˜0.5-6 keV globally distributed ENA spectral indices could be represented as single power laws over much of the sky, our new results indicate that this is an over-simplification because the spectral indices have an energy and latitude dependence. This dependence is an important factor that must be taken into consideration by models and simulations that seek to map the IBEX ENA observations back to the latitudinal profile of the SW speed structure observed in the inner heliosphere.

  18. ENERGY AND ANGULAR DEPENDENCE OF RADIOPHOTOLUMINESCENT GLASS DOSEMETERS FOR EYE LENS DOSIMETRY.

    PubMed

    Silva, E H; Knežević, Ž; Struelens, L; Covens, P; Ueno, S; Vanhavere, F; Buls, N

    2016-09-01

    Recent studies demonstrated that lens opacities can occur at lower radiation doses than previously accepted. In view of these studies, the International Commission of Radiological Protection recommended in 2011 to reduce the eye lens dose limit from 150 mSv/y to 20 mSv/y. This implies in the need of monitoring doses received by the eye lenses. In this study, small rod radiophotoluminescent glass dosemeters (GD-300 series; AGC, Japan) were characterized in terms of their energy (ISO 4037 X-rays narrow spectrum series, S-Cs and S-Co) and angular dependence (0  up to 90 degrees, with 2 ISO energies: N-60 and S-Cs). All acquisitions were performed at SCK•CEN-Belgium, using the ORAMED proposed cylindrical phantom. For selected energies (N-60, N-80, N-100, N-120 and N-250), the response of dosemeters irradiated on the ISO water slab phantom, at the Ruđer Bošković Institute-Croatia, was compared to those irradiated on the cylindrical phantom. GD-300 series showed good energy dependence, relative to S-Cs, on the cylindrical phantom. From 0 up to 45 degrees, the dosemeters showed no significant angular dependence, regardless whether they were tested when placed vertically or horizontally on the cylindrical phantom. However, at higher angles, some angular dependence was observed, mainly when the dosemeters were irradiated with low-energy photons (N-60). Results showed that GD-300 series have good properties related to Hp(3), although some improvements may be necessary.

  19. Analysis of incident-energy dependence of delayed neutron yields in actinides

    SciTech Connect

    Nasir, Mohamad Nasrun bin Mohd Metorima, Kouhei Ohsawa, Takaaki Hashimoto, Kengo

    2015-04-29

    The changes of delayed neutron yields (ν{sub d}) of Actinides have been analyzed for incident energy up to 20MeV using realized data of precursor after prompt neutron emission, from semi-empirical model, and delayed neutron emission probability data (P{sub n}) to carry out a summation method. The evaluated nuclear data of the delayed neutron yields of actinide nuclides are still uncertain at the present and the cause of the energy dependence has not been fully understood. In this study, the fission yields of precursor were calculated considering the change of the fission fragment mass yield based on the superposition of fives Gaussian distribution; and the change of the prompt neutrons number associated with the incident energy dependence. Thus, the incident energy dependent behavior of delayed neutron was analyzed.The total number of delayed neutron is expressed as ν{sub d}=∑Y{sub i} • P{sub ni} in the summation method, where Y{sub i} is the mass yields of precursor i and P{sub ni} is the delayed neutron emission probability of precursor i. The value of Y{sub i} is derived from calculation of post neutron emission mass distribution using 5 Gaussian equations with the consideration of large distribution of the fission fragments. The prompt neutron emission ν{sub p} increases at higher incident-energy but there are two different models; one model says that the fission fragment mass dependence that prompt neutron emission increases uniformly regardless of the fission fragments mass; and the other says that the major increases occur at heavy fission fragments area. In this study, the changes of delayed neutron yields by the two models have been investigated.

  20. Energy-Gap Dependence on the Mn Mole Fraction and Temperature in Cdmnte Crystal

    SciTech Connect

    Kim, K.; Bolotnikov, A; Camarda, G; Yang, G; Hossain, A; Cui, Y; James, r; Hong, J; Kim, S

    2009-01-01

    We measured the dependence of the energy gap in Bridgman-grown Cd1-xMnxTe crystals, 0 {le} x {le} 0.25, on the Mn mole fraction and temperatures from 40 to 300 K. We determined the Mn mole fraction and energy gap, respectively, from electron probe microanalysis and near-infrared Fourier-transform infrared transmission spectra. The energy gap increased linearly with an increase in the Mn content in the crystal and with a decrease in temperature. We formulated new equations from these experimental results, wherein we expressed the energy gap as a function of Mn mole fraction and temperature. Also, we compare our findings with published results.

  1. DNA-length-dependent fluorescent sensing based on energy transfer in self-assembled multilayers.

    PubMed

    Sun, Xiang-Ying; Liu, Bin; Sun, Yan-Feng; Yu, Yaming

    2014-11-15

    In this paper, a novel DNA-length-dependent fluorescent sensor was constructed based on the fluorescence resonance energy transfer. In the self-assembled multilayers (Quartz/GO/PDDA/Tx-DNA/PDDA/ZnO@CdS), ZnO@CdS and graphene oxide(GO) were employed as an energy donor and an energy acceptor, respectively. Single-stranded Tx-DNA (x represents different chain length of DNA) and poly(diallydimethylammonium) chloride (PDDA) were used as a linker. In the presence of complementary Px-DNA, the formation of double-stranded DNA leads to a change in chain length and achieves the purpose of changing the distance between ZnO@CdS and GO. Thereby, it enhances the efficiency of energy transfer between ZnO@CdS and GO resulting in the quench of fluorescence of ZnO@CdS, and thus different length DNA sequence was detected.

  2. Model dependence of the neutrino-deuteron disintegration cross sections at low energies

    SciTech Connect

    Mosconi, B.; Ricci, P.; Truhlik, E.; Vogel, P.

    2007-04-15

    Model dependence of the reaction rates for the weak breakup of deuterons by low-energy neutrinos is studied starting from the cross sections derived from potential models and also from pionless effective field theory. Choosing the spread of the reaction yields, caused basically by the different ways the two-body currents are treated, as a measure of the model-dependent uncertainty, we conclude that the breakup reactions are {approx}2-3% uncertain and that even the ratio of the charged to neutral current reaction rates is also {approx}2% uncertain.

  3. Novel scatter compensation of list-mode PET data using spatial and energy dependent corrections.

    PubMed

    Guérin, Bastien; El Fakhri, Georges

    2011-03-01

    With the widespread use of positron emission tomography (PET) crystals with greatly improved energy resolution (e.g., 11.5% with LYSO as compared to 20% with BGO) and of list-mode acquisitions, the use of the energy of individual events in scatter correction schemes becomes feasible. We propose a novel scatter approach that incorporates the energy of individual photons in the scatter correction and reconstruction of list-mode PET data in addition to the spatial information presently used in clinical scanners. First, we rewrite the Poisson likelihood function of list-mode PET data including the energy distributions of primary and scatter coincidences and show that this expression yields an MLEM reconstruction algorithm containing both energy and spatial dependent corrections. To estimate the spatial distribution of scatter coincidences we use the single scatter simulation (SSS). Next, we derive two new formulae which allow estimation of the 2-D (coincidences) energy probability density functions (E-PDF) of primary and scatter coincidences from the 1-D (photons) E-PDFs associated with each photon. We also describe an accurate and robust object-specific method for estimating these 1-D E-PDFs based on a decomposition of the total energy spectra detected across the scanner into primary and scattered components. Finally, we show that the energy information can be used to accurately normalize the scatter sinogram to the data. We compared the performance of this novel scatter correction incorporating both the position and energy of detected coincidences to that of the traditional approach modeling only the spatial distribution of scatter coincidences in 3-D Monte Carlo simulations of a medium cylindrical phantom and a large, nonuniform NCAT phantom. Incorporating the energy information in the scatter correction decreased bias in the activity distribution estimation by ~20% and ~40% in the cold regions of the large NCAT phantom at energy resolutions 11.5% and 20% at 511 ke

  4. Space Radiation Absorbed Dose Distribution in a Human Phantom Torso

    NASA Technical Reports Server (NTRS)

    Badhwar, G. D.; Yang, T.; Atwell, W.

    2000-01-01

    The flight of a human phantom torso with head that containing active dosimeters at 5 organ sites and 1400 TLDs distributed in 34 1" thick sections is described. Experimental dose rates and quality factors are compared with calculations for shielding distributions at the sites using the Computerized Anatomical Male (CAM) model. The measurements were complemented with those obtained from other instruments. These results have provided the most comprehensive data set to map the dose distribution inside a human and to assess the accuracy of radiation transport models and astronaut radiation risk.

  5. Quantification of energy losses in organic solar cells from temperature-dependent device characteristics

    NASA Astrophysics Data System (ADS)

    Hörmann, Ulrich; Kraus, Julia; Gruber, Mark; Schuhmair, Christoph; Linderl, Theresa; Grob, Stefan; Kapfinger, Stephan; Klein, Konrad; Stutzman, Martin; Krenner, Hubert J.; Brütting, Wolfgang

    2013-12-01

    Owing to the excitonic nature of photoexcitations in organic semiconductors, the working mechanism of organic solar cells relies on the donor-acceptor (D/A) concept enabling photoinduced charge transfer at the interface between two organic materials with suitable energy-level alignment. However, the introduction of such a heterojunction is accompanied by additional energy losses compared to an inorganic homojunction cell due to the presence of a charge-transfer (CT) state at the D/A interface. By careful examination of planar heterojunctions of the molecular semiconductors diindenoperylene (DIP) and C60 we demonstrate that three different analysis techniques of the temperature dependence of solar-cell characteristics yield reliable values for the effective photovoltaic energy gap at the D/A interface. The retrieved energies are shown to be consistent with direct spectroscopic measurements and the D/A energy-level offset determined by photoemission spectroscopy. Furthermore, we verify the widespread assumption that the activation energy of the dark saturation current ΔE and the CT energy ECT may be regarded as identical. The temperature-dependent analysis of open-circuit voltage VOC and dark saturation current is then applied to a variety of molecular planar heterojunctions. The congruency of ΔE and ECT is again found for all material systems with the exception of copper phthalocyanine/C60. The general rule of thumb for organic semiconductor heterojunctions, that VOC at room temperature is roughly half a volt below the CT energy, is traced back to comparable intermolecular electronic coupling in all investigated systems.

  6. Extrapolation chamber mounted on perspex for calibration of high energy photon and electron beams from a clinical linear accelerator

    PubMed Central

    Ravichandran, R.; Binukumar, J. P.; Sivakumar, S. S.; Krishnamurthy, K.; Davis, C. A.

    2009-01-01

    The objective of the present study is to establish radiation standards for absorbed doses, for clinical high energy linear accelerator beams. In the nonavailability of a cobalt-60 beam for arriving at Nd, water values for thimble chambers, we investigated the efficacy of perspex mounted extrapolation chamber (EC) used earlier for low energy x-rays and beta dosimetry. Extrapolation chamber with facility for achieving variable electrode separations 10.5mm to 0.5mm using micrometer screw was used for calibrations. Photon beams 6 MV and 15 MV and electron beams 6 MeV and 15 MeV from Varian Clinac linacs were calibrated. Absorbed Dose estimates to Perspex were converted into dose to solid water for comparison with FC 65 ionisation chamber measurements in water. Measurements made during the period December 2006 to June 2008 are considered for evaluation. Uncorrected ionization readings of EC for all the radiation beams over the entire period were within 2% showing the consistency of measurements. Absorbed doses estimated by EC were in good agreement with in-water calibrations within 2% for photons and electron beams. The present results suggest that extrapolation chambers can be considered as an independent measuring system for absorbed dose in addition to Farmer type ion chambers. In the absence of standard beam quality (Co-60 radiations as reference Quality for Nd,water) the possibility of keeping EC as Primary Standards for absorbed dose calibrations in high energy radiation beams from linacs should be explored. As there are neither Standard Laboratories nor SSDL available in our country, we look forward to keep EC as Local Standard for hospital chamber calibrations. We are also participating in the IAEA mailed TLD intercomparison programme for quality audit of existing status of radiation dosimetry in high energy linac beams. The performance of EC has to be confirmed with cobalt-60 beams by a separate study, as linacs are susceptible for minor variations in dose

  7. Energy dependence of nuclear charge distribution in neutron induced fission of Z-even nuclei

    NASA Astrophysics Data System (ADS)

    Roshchenko, V. A.; Piksaikin, V. M.; Isaev, S. G.; Goverdovski, A. A.

    2006-07-01

    For the first time the distribution of nuclear charge of fission products with mass numbers 87, 88, 89, 91, 93, 94, 95, 137, 138, 139, and 140 and their complementary products have been studied for neutron induced fission of U235 and Pu239 in the energy range from thermal up to 1.2 MeV. The energy dependences of the cumulative yields of Br87, Br88, Br89, Br91, Kr93, Rb94, Rb95, I137, I138, I139, and I140 have been obtained by delayed neutron measurements. The most probable charge ZP(A)in the appropriate isobaric β-decay chains was estimated. The results were analyzed in terms of the deviation ΔZP(A') of the most probable charge of isobaric β-decay chains from the unchanged charge distribution before prompt neutron emission (nuclear charge polarization) and they are compared with experimental data of other authors and with predictions from Nethaway's ZP-formula and Wahl's ZP-model. We show that the nuclear charge polarization of primary fission fragments <ΔZP(A')> before prompt neutron evaporation decreases as the excitation energy of the compound nucleus increases. This decrease is more pronounced for fission of U235. The energy dependencies of ΔZP(A') and ΔZP(ZP) obtained in the present work show an attenuation of the odd-even effects in the charge distribution as the excitation energy of the compound nucleus increases.

  8. Energy Dependence and Scaling Property of Localization Length near a Gapped Flat Band

    NASA Astrophysics Data System (ADS)

    Ge, Li; Tureci, Hakan

    Using a tight-binding model for a one-dimensional Lieb lattice, we show that the localization length near a gapped flat band behaves differently from the typical Urbach tail in a band gap: instead of reducing monotonically as the energy E moves away from the flat band energy Ef, the presence of the flat band causes a nonmonotonic energy dependence of the localization length. This energy dependence follows a scaling property when the energy is within the spread (W) of uniformly distributed diagonal disorder, i.e. the localization length is only a function of (E-Ef)/W. Several other lattices are compared to distinguish the effect of the flat band on the localization length, where we eliminate, shift, or duplicate the flat band, without changing the dispersion relations of other bands. Using the top right element of the Green's matrix, we derive an analytical relation between the density of states and the localization length, which shines light on these properties of the latter, including a summation rule for its inverse. This work is partially supported by NSF under Grant No. DMR-1506987.

  9. Distance dependence of the energy transfer rate from a single semiconductor nanostructure to graphene.

    PubMed

    Federspiel, François; Froehlicher, Guillaume; Nasilowski, Michel; Pedetti, Silvia; Mahmood, Ather; Doudin, Bernard; Park, Serin; Lee, Jeong-O; Halley, David; Dubertret, Benoît; Gilliot, Pierre; Berciaud, Stéphane

    2015-02-11

    The near-field Coulomb interaction between a nanoemitter and a graphene monolayer results in strong Förster-type resonant energy transfer and subsequent fluorescence quenching. Here, we investigate the distance dependence of the energy transfer rate from individual, (i) zero-dimensional CdSe/CdS nanocrystals and (ii) two-dimensional CdSe/CdS/ZnS nanoplatelets to a graphene monolayer. For increasing distances d, the energy transfer rate from individual nanocrystals to graphene decays as 1/d(4). In contrast, the distance dependence of the energy transfer rate from a two-dimensional nanoplatelet to graphene deviates from a simple power law but is well described by a theoretical model, which considers a thermal distribution of free excitons in a two-dimensional quantum well. Our results show that accurate distance measurements can be performed at the single particle level using graphene-based molecular rulers and that energy transfer allows probing dimensionality effects at the nanoscale. PMID:25607231

  10. Centrality dependence of high energy jets in p+Pb collisions at energies available at the CERN Large Hadron Collider

    DOE PAGES

    Bzdak, Adam; Skokov, Vladimir; Bathe, Stefan

    2016-04-08

    We investigate the recently measured centrality dependence of high energy jets in proton-lead collisions at the LHC. Here, we hypothesize that events with jets of very high energy (a few hundred GeV) are characterized by a suppressed number of soft particles, thus shifting these events into more peripheral bins. This naturally results in the suppression (enhancement) of the nuclear modification factor, RpA, in central (peripheral) collisions. Our calculations suggest that a moderate suppression of the order of 20%, for 103 GeV jets, can quantitatively reproduce the experimental data. Finally, we further extract the suppression factor as a function of jetmore » energy and test our conjecture using available RpA data for various centralities.« less

  11. Centrality dependence of high energy jets in p +Pb collisions at energies available at the CERN Large Hadron Collider

    NASA Astrophysics Data System (ADS)

    Bzdak, Adam; Skokov, Vladimir; Bathe, Stefan

    2016-04-01

    The recently measured centrality dependence of high energy jets in proton-lead collisions at the CERN Large Hadron Collider (LHC) is investigated. We hypothesize that events with jets of very high energy (a few hundred GeV) are characterized by a suppressed number of soft particles, thus shifting these events into more peripheral bins. This naturally results in the suppression (enhancement) of the nuclear modification factor, Rp A, in central (peripheral) collisions. Our calculations suggest that a moderate suppression of the order of 20 % , for 103 GeV jets, can quantitatively reproduce the experimental data. We further extract the suppression factor as a function of jet energy and test our conjecture using available Rp A data for various centralities.

  12. Mechanism for the thermal dependence of the Cr to Nd energy transfer in garnets

    NASA Technical Reports Server (NTRS)

    Armagan, Guzin; Di Bartolo, Baldassare

    1988-01-01

    The temperature dependence of the Cr-Nd energy transfer is found to be due to the thermal variation of the radiative decay probability of Cr. The validity of this conjecture is checked in the Gd3Sc2Ga3O12 and CaMg2Y2Ge3O12 crystals. It is also found that above 200 K, the nonradiative energy transfer rate from Cr to Nd is greater in Gd3Sc2Ga3O12 than in CaMg2Y2Ge3O12.

  13. Energy-dependent dipole form factor in a QCD-inspired model

    NASA Astrophysics Data System (ADS)

    Bahia, C. A. S.; Broilo, M.; Luna, E. G. S.

    2016-04-01

    We consider the effect of an energy-dependent dipole form factor in the high-energy behavior of the forward amplitude. The connection between the semihard parton-level dynamics and the hadron-hadron scattering is established by an eikonal QCD-based model. Our results for the proton-proton (pp) and antiproton-proton (¯pp) total cross sections, σpp,\\bar{pp}tot(s), obtained using the CTEQ6L1 parton distribution function, are consistent with the recent data from the TOTEM experiment.

  14. On the energy dependence of proton beam extraction with a bent crystal

    NASA Astrophysics Data System (ADS)

    Arduini, G.; Elsener, K.; Fidecaro, G.; Gyr, M.; Herr, W.; Klem, J.; Mikkelsen, U.; Weisse, E.

    1998-03-01

    Proton beam extraction from the CERN SPS by means of a bent silicon crystal is reported at three different energies, 14 GeV, 120 GeV and 270 GeV. The experimental results are compared to computer simulations which contain a sound model of the SPS accelerator as well as the channeling phenomena in bent crystals. The overall energy dependence of crystal assisted proton beam extraction is understood and provides the basis to discuss such a scheme for future accelerators. © 1998

  15. Rate dependence of temperature fields and energy dissipations in non-static pseudoelasticity

    NASA Astrophysics Data System (ADS)

    Yan, Y.; Yin, H.; Sun, Q. P.; Huo, Y.

    2012-11-01

    The temperature fields and the energy dissipations of shape memory alloys during the stress-induced martensitic transformations are studied theoretically and experimentally. The effect of the loading rate is analyzed. It was found that the temperature field inside a shape memory alloy sample varies strongly in space and time. The increase rate of the temperature is given by the difference between the rate of the latent heat release and the rate of the heat convection and conduction. The notion and the rate dependence of the energy dissipation are discussed in connection with the stress-strain hysteresis, the entropy production, and the Clausius-Duhem inequality.

  16. Monte Carlo analysis of energy dependent anisotropy of bremsstrahlung x-ray spectra

    SciTech Connect

    Kakonyi, Robert; Erdelyi, Miklos; Szabo, Gabor

    2009-09-15

    The energy resolved emission angle dependence of x-ray spectra was analyzed by MCNPX (Monte Carlo N particle Monte Carlo) simulator. It was shown that the spectral photon flux had a maximum at a well-defined emission angle due to the anisotropy of the bremsstrahlung process. The higher the relative photon energy, the smaller the emission angle belonging to the maximum was. The trends predicted by the Monte Carlo simulations were experimentally verified. The Monte Carlo results were compared to both the Institute of Physics and Engineering in Medicine spectra table and the SPEKCALCV1.0 code.

  17. Single-molecule derivation of salt dependent base-pair free energies in DNA.

    PubMed

    Huguet, Josep M; Bizarro, Cristiano V; Forns, Núria; Smith, Steven B; Bustamante, Carlos; Ritort, Felix

    2010-08-31

    Accurate knowledge of the thermodynamic properties of nucleic acids is crucial to predicting their structure and stability. To date most measurements of base-pair free energies in DNA are obtained in thermal denaturation experiments, which depend on several assumptions. Here we report measurements of the DNA base-pair free energies based on a simplified system, the mechanical unzipping of single DNA molecules. By combining experimental data with a physical model and an optimization algorithm for analysis, we measure the 10 unique nearest-neighbor base-pair free energies with 0.1 kcal mol(-1) precision over two orders of magnitude of monovalent salt concentration. We find an improved set of standard energy values compared with Unified Oligonucleotide energies and a unique set of 10 base-pair-specific salt-correction values. The latter are found to be strongest for AA/TT and weakest for CC/GG. Our unique energy values and salt corrections improve predictions of DNA unzipping forces and are fully compatible with melting temperatures for oligos. The method should make it possible to obtain free energies, enthalpies, and entropies in conditions not accessible by bulk methodologies. PMID:20716688

  18. Dependence of hydropower energy generation on forests in the Amazon Basin at local and regional scales.

    PubMed

    Stickler, Claudia M; Coe, Michael T; Costa, Marcos H; Nepstad, Daniel C; McGrath, David G; Dias, Livia C P; Rodrigues, Hermann O; Soares-Filho, Britaldo S

    2013-06-01

    Tropical rainforest regions have large hydropower generation potential that figures prominently in many nations' energy growth strategies. Feasibility studies of hydropower plants typically ignore the effect of future deforestation or assume that deforestation will have a positive effect on river discharge and energy generation resulting from declines in evapotranspiration (ET) associated with forest conversion. Forest loss can also reduce river discharge, however, by inhibiting rainfall. We used land use, hydrological, and climate models to examine the local "direct" effects (through changes in ET within the watershed) and the potential regional "indirect" effects (through changes in rainfall) of deforestation on river discharge and energy generation potential for the Belo Monte energy complex, one of the world's largest hydropower plants that is currently under construction on the Xingu River in the eastern Amazon. In the absence of indirect effects of deforestation, simulated deforestation of 20% and 40% within the Xingu River basin increased discharge by 4-8% and 10-12%, with similar increases in energy generation. When indirect effects were considered, deforestation of the Amazon region inhibited rainfall within the Xingu Basin, counterbalancing declines in ET and decreasing discharge by 6-36%. Under business-as-usual projections of forest loss for 2050 (40%), simulated power generation declined to only 25% of maximum plant output and 60% of the industry's own projections. Like other energy sources, hydropower plants present large social and environmental costs. Their reliability as energy sources, however, must take into account their dependence on forests.

  19. Berberine regulates neurite outgrowth through AMPK-dependent pathways by lowering energy status

    SciTech Connect

    Lu, Jiaqi; Cao, Yuanzhao; Cheng, Kuoyuan; Xu, Bo; Wang, Tianchang; Yang, Qi; Yang, Qin; Feng, Xudong; Xia, Qing

    2015-06-10

    As a widely used anti-bacterial agent and a metabolic inhibitor as well as AMP-activated protein kinase (AMPK) activator, berberine (BBR) has been shown to cross the blood–brain barrier. Its efficacy has been investigated in various disease models of the central nervous system. Neurite outgrowth is critical for nervous system development and is a highly energy-dependent process regulated by AMPK-related pathways. In the present study, we aimed to investigate the effects of BBR on AMPK activation and neurite outgrowth in neurons. The neurite outgrowth of primary rat cortical neurons at different stages of polarization was monitored after exposure of BBR. Intracellular energy level, AMPK activation and polarity-related pathways were also inspected. The results showed that BBR suppressed neurite outgrowth and affected cytoskeleton stability in the early stages of neuronal polarization, which was mediated by lowered energy status and AMPK activation. Liver kinase B1 and PI3K–Akt–GSK3β signaling pathways were also involved. In addition, mitochondrial dysfunction and endoplasmic reticulum stress contributed to the lowered energy status induced by BBR. This study highlighted the knowledge of the complex activities of BBR in neurons and corroborated the significance of energy status during the neuronal polarization. - Highlights: • BBR inhibited neurite outgrowth in early stages of neuronal development. • Lowered neuronal energy status was induced by BBR treatment. • Neuronal energy stress induced by BBR activated AMPK-related pathways. • BBR induced mitochondrial dysfunction and endoplasmic reticulum stress.

  20. Dependence of hydropower energy generation on forests in the Amazon Basin at local and regional scales.

    PubMed

    Stickler, Claudia M; Coe, Michael T; Costa, Marcos H; Nepstad, Daniel C; McGrath, David G; Dias, Livia C P; Rodrigues, Hermann O; Soares-Filho, Britaldo S

    2013-06-01

    Tropical rainforest regions have large hydropower generation potential that figures prominently in many nations' energy growth strategies. Feasibility studies of hydropower plants typically ignore the effect of future deforestation or assume that deforestation will have a positive effect on river discharge and energy generation resulting from declines in evapotranspiration (ET) associated with forest conversion. Forest loss can also reduce river discharge, however, by inhibiting rainfall. We used land use, hydrological, and climate models to examine the local "direct" effects (through changes in ET within the watershed) and the potential regional "indirect" effects (through changes in rainfall) of deforestation on river discharge and energy generation potential for the Belo Monte energy complex, one of the world's largest hydropower plants that is currently under construction on the Xingu River in the eastern Amazon. In the absence of indirect effects of deforestation, simulated deforestation of 20% and 40% within the Xingu River basin increased discharge by 4-8% and 10-12%, with similar increases in energy generation. When indirect effects were considered, deforestation of the Amazon region inhibited rainfall within the Xingu Basin, counterbalancing declines in ET and decreasing discharge by 6-36%. Under business-as-usual projections of forest loss for 2050 (40%), simulated power generation declined to only 25% of maximum plant output and 60% of the industry's own projections. Like other energy sources, hydropower plants present large social and environmental costs. Their reliability as energy sources, however, must take into account their dependence on forests. PMID:23671098

  1. Temperature dependence of the energy gap of semiconductors in the low-temperature limit.

    PubMed

    Cardona, Manuel; Meyer, T A; Thewalt, M L W

    2004-05-14

    The temperature dependence of the electronic states and energy gaps of semiconductors is an old but still important experimental and theoretical topic. Remarkably, extant results do not clarify the asymptotic T-->0 behavior. Recent breakthroughs in the spectroscopy of enriched 28Si allow us to measure changes in the band gap over the liquid 4He temperature range with an astounding precision of one part in 10(8), revealing a T4.0+/-0.2 decrease with increasing T. This is in excellent agreement with a theoretical argument predicting an exponent of 4. This power law should apply, in the low temperature limit, to the temperature dependence of the energies of all electronic states in semiconductors and insulators.

  2. LETTER TO THE EDITOR: The temperature dependence of the spin - Peierls energy gap in ?

    NASA Astrophysics Data System (ADS)

    Lussier, J.-G.; Coad, S. M.; McMorrow, D. F.; McK Paul, D.

    1996-01-01

    We have studied the temperature dependence of the spin - Peierls (SP) energy gap in a single crystal of 0953-8984/8/4/003/img8 using cold neutrons. Our measurements enable us to examine the scaling relationship between the magnitude of the SP gap and the intensity of the structural superlattice peak in the vicinity of the transition temperature (0953-8984/8/4/003/img9). We also discuss our data in the context of recent numerical calculations for which different scaling laws are obtained depending on the magnitude of the intrachain next-nearest-neighbour interaction in a Heisenberg spin-chain Hamiltonian. The consequence of two-dimensional correlations and the possible existence above 0953-8984/8/4/003/img9 of a second low-lying energy gap due to frustration are considered.

  3. Energy density dependence of hydrogen combustion efficiency in atmospheric pressure microwave plasma

    SciTech Connect

    Yoshida, T.; Ezumi, N.; Sawada, K.; Tanaka, Y.; Tanaka, M.; Nishimura, K.

    2015-03-15

    The recovery of tritium in nuclear fusion plants is a key issue for safety. So far, the oxidation procedure using an atmospheric pressure plasma is expected to be part of the recovery method. In this study, in order to clarify the mechanism of hydrogen oxidation by plasma chemistry, we have investigated the dependence of hydrogen combustion efficiency on gas flow rate and input power in the atmospheric pressure microwave plasma. It has been found that the combustion efficiency depends on energy density of absorbed microwave power. Hence, the energy density is considered as a key parameter for combustion processes. Also neutral gas temperatures inside and outside the plasma were measured by an optical emission spectroscopy method and thermocouple. The result shows that the neutral gas temperature in the plasma is much higher than the outside temperature of plasma. The high neutral gas temperature may affect the combustion reaction. (authors)

  4. Correlation between surface chemistry and ion energy dependence of the etch yield in multicomponent oxides etching

    SciTech Connect

    Berube, P.-M.; Poirier, J.-S.; Margot, J.; Stafford, L.; Ndione, P. F.; Chaker, M.; Morandotti, R.

    2009-09-15

    The influence of surface chemistry in plasma etching of multicomponent oxides was investigated through measurements of the ion energy dependence of the etch yield. Using pulsed-laser-deposited Ca{sub x}Ba{sub (1-x)}Nb{sub 2}O{sub 6} (CBN) and SrTiO{sub 3} thin films as examples, it was found that the etching energy threshold shifts toward values larger or smaller than the sputtering threshold depending on whether or not ion-assisted chemical etching is the dominant etching pathway and whether surface chemistry is enhancing or inhibiting desorption of the film atoms. In the case of CBN films etched in an inductively coupled Cl{sub 2} plasma, it is found that the chlorine uptake is inhibiting the etching reaction, with the desorption of nonvolatile NbCl{sub 2} and BaCl{sub 2} compounds being the rate-limiting step.

  5. Energy Dependence of Millisecond Timing Phenomena in the Z-Source GX 349+2

    NASA Astrophysics Data System (ADS)

    Michelson, Peter

    As part of a program to search for temporal signatures of Comptonizing clouds in Z sources, and other energy-dependent properties of high frequency phenomena, we are requesting an observation of GX 349+2 with high temporal and moderate spectral resolution. We will measure hard photon time lags and the X-ray variability coherence as a function of Z position. This observation, when combined with our previous observation of GX 340+0 and archival observations of the other Z sources, can constrain the geometries of scattering clouds in these systems, which are invoked to explain the spectral variations seen as well as the non- detection of coherent pulsations. These observations will also allow the study of the energy dependence of QPO as they evolve along the branches of the Z.

  6. Energy-Dependent Ionization States of Shock-Accelerated Particles in the Solar Corona

    NASA Technical Reports Server (NTRS)

    Reames, Donald V.; Ng, C. K.; Tylka, A. J.

    2000-01-01

    We examine the range of possible energy dependence of the ionization states of ions that are shock-accelerated from the ambient plasma of the solar corona. If acceleration begins in a region of moderate density, sufficiently low in the corona, ions above about 0.1 MeV/amu approach an equilibrium charge state that depends primarily upon their speed and only weakly on the plasma temperature. We suggest that the large variations of the charge states with energy for ions such as Si and Fe observed in the 1997 November 6 event are consistent with stripping in moderately dense coronal. plasma during shock acceleration. In the large solar-particle events studied previously, acceleration occurs sufficiently high in the corona that even Fe ions up to 600 MeV/amu are not stripped of electrons.

  7. Gafchromic EBT3 film dosimetry in electron beams - energy dependence and improved film read-out.

    PubMed

    Sipilä, Petri; Ojala, Jarkko; Kaijaluoto, Sampsa; Jokelainen, Ilkka; Kosunen, Antti

    2016-01-01

    For megavoltage photon radiation, the fundamental dosimetry characteristics of Gafchromic EBT3 film were determined in 60Co gamma ray beam with addition of experimental and Monte Carlo (MC)-simulated energy dependence of the film for 6 MV photon beam and 6 MeV, 9 MeV, 12 MeV, and 16 MeV electron beams in water phantom. For the film read-out, two phase correction of scanner sensitivity was applied: a matrix correction for scanning area and dose-dependent correction by iterative procedure. With these corrections, the uniformity of response can be improved to be within ± 50 pixel values (PVs). To improve the read-out accuracy, a procedure with flipped film orientations was established. With the method, scanner uniformity can be improved further and dust particles, scratches and/or dirt on scan-ner glass can be detected and eliminated. Responses from red and green channels were averaged for read-out, which decreased the effect of noise present in values from separate channels. Since the signal level with the blue channel is considerably lower than with other channels, the signal variation due to different perturbation effects increases the noise level so that the blue channel is not recommended to be used for dose determination. However, the blue channel can be used for the detection of emulsion thickness variations for film quality evaluations with unexposed films. With electron beams ranging from 6 MeV to 16 MeV and at reference measurement conditions in water, the energy dependence of the EBT3 film is uniform within 0.5%, with uncertainties close to 1.6% (k = 2). Including 6 MV photon beam and the electron beams mentioned, the energy dependence is within 1.1%. No notable differences were found between the experimental and MC-simulated responses, indicating negligible change in intrinsic energy dependence of the EBT3 film for 6 MV photon beam and 6 MeV-16 MeV electron beams. Based on the dosimetric characteristics of the EBT3 film, the read-out procedure established

  8. Secondary bremsstrahlung and the energy-conservation aspects of kerma in photon-irradiated media.

    PubMed

    Kumar, Sudhir; Nahum, Alan E

    2016-02-01

    Kerma, collision kerma and absorbed dose in media irradiated by megavoltage photons are analysed with respect to energy conservation. The user-code DOSRZnrc was employed to compute absorbed dose D, kerma K and a special form of kerma, K ncpt, obtained by setting the charged-particle transport energy cut-off very high, thereby preventing the generation of 'secondary bremsstrahlung' along the charged-particle paths. The user-code FLURZnrc was employed to compute photon fluence, differential in energy, from which collision kerma, K col and K were derived. The ratios K/D, K ncpt/D and K col/D have thereby been determined over a very large volumes of water, aluminium and copper irradiated by broad, parallel beams of 0.1 to 25 MeV monoenergetic photons, and 6, 10 and 15 MV 'clinical' radiotherapy qualities. Concerning depth-dependence, the 'area under the kerma, K, curve' exceeded that under the dose curve, demonstrating that kerma does not conserve energy when computed over a large volume. This is due to the 'double counting' of the energy of the secondary bremsstrahlung photons, this energy being (implicitly) included in the kerma 'liberated' in the irradiated medium, at the same time as this secondary bremsstrahlung is included in the photon fluence which gives rise to kerma elsewhere in the medium. For 25 MeV photons this 'violation' amounts to 8.6%, 14.2% and 25.5% in large volumes of water, aluminium and copper respectively but only 0.6% for a 'clinical' 6 MV beam in water. By contrast, K col/D and K ncpt/D, also computed over very large phantoms of the same three media, for the same beam qualities, are equal to unity within (very low) statistical uncertainties, demonstrating that collision kerma and the special type of kerma, K ncpt, do conserve energy over a large volume. A comparison of photon fluence spectra for the 25 MeV beam at a depth of  ≈51 g cm−2 for both very high and very low charged-particle transport cut-offs reveals the considerable

  9. Secondary bremsstrahlung and the energy-conservation aspects of kerma in photon-irradiated media

    NASA Astrophysics Data System (ADS)

    Kumar, Sudhir; Nahum, Alan E.

    2016-02-01

    Kerma, collision kerma and absorbed dose in media irradiated by megavoltage photons are analysed with respect to energy conservation. The user-code DOSRZnrc was employed to compute absorbed dose D, kerma K and a special form of kerma, K ncpt, obtained by setting the charged-particle transport energy cut-off very high, thereby preventing the generation of ‘secondary bremsstrahlung’ along the charged-particle paths. The user-code FLURZnrc was employed to compute photon fluence, differential in energy, from which collision kerma, K col and K were derived. The ratios K/D, K ncpt/D and K col/D have thereby been determined over a very large volumes of water, aluminium and copper irradiated by broad, parallel beams of 0.1 to 25 MeV monoenergetic photons, and 6, 10 and 15 MV ‘clinical’ radiotherapy qualities. Concerning depth-dependence, the ‘area under the kerma, K, curve’ exceeded that under the dose curve, demonstrating that kerma does not conserve energy when computed over a large volume. This is due to the ‘double counting’ of the energy of the secondary bremsstrahlung photons, this energy being (implicitly) included in the kerma ‘liberated’ in the irradiated medium, at the same time as this secondary bremsstrahlung is included in the photon fluence which gives rise to kerma elsewhere in the medium. For 25 MeV photons this ‘violation’ amounts to 8.6%, 14.2% and 25.5% in large volumes of water, aluminium and copper respectively but only 0.6% for a ‘clinical’ 6 MV beam in water. By contrast, K col/D and K ncpt/D, also computed over very large phantoms of the same three media, for the same beam qualities, are equal to unity within (very low) statistical uncertainties, demonstrating that collision kerma and the special type of kerma, K ncpt, do conserve energy over a large volume. A comparison of photon fluence spectra for the 25 MeV beam at a depth of  ≈51 g cm-2 for both very high and very low charged-particle transport cut

  10. The energy balance relation for weak solutions of the density-dependent Navier-Stokes equations

    NASA Astrophysics Data System (ADS)

    Leslie, T. M.; Shvydkoy, R.

    2016-09-01

    We consider the incompressible inhomogeneous Navier-Stokes equations with constant viscosity coefficient and density which is bounded and bounded away from zero. We show that the energy balance relation for this system holds for weak solutions if the velocity, density, and pressure belong to a range of Besov spaces of smoothness 1/3. A density-dependent version of the classical Kármán-Howarth-Monin relation is derived.

  11. Time delay of light signals in an energy-dependent spacetime metric

    SciTech Connect

    Grillo, A. F.; Luzio, E.; Mendez, F.

    2008-05-15

    In this paper we review the problem of time delay of photons propagating in a spacetime with a metric that explicitly depends on the energy of the particles (gravity-rainbow approach). We show that corrections due to this approach--which is closely related to the double special relativity proposal--produce for small redshifts (z<<1) smaller time delays than in the generic Lorentz invariance violating case.

  12. Angular dependence of recoil proton polarization in high-energy \\gamma d \\to p n

    SciTech Connect

    X. Jiang; J. Arrington; F. Benmokhtar; A. Camsonne; J.P. Chen; S. Choi; E. Chudakov; F. Cusanno; A. Deur; D. Dutta; F. Garibaldi; D. Gaskell; O. Gayou; R. Gilman; C. Glashauser; D. Hamilton; O. Hansen; D.W. Higinbotham; R.J. Holt; C.W. de Jager; M.K. Jones; L.J. Kaufman; E.R. Kinney; K. Kramer; L. Lagamba; R. de Leo; J. Lerose; D. Lhuillier; R. Lindgren; N. Liyanage; K. McCormick; Z.-E. Meziani; R. Michaels; B. Moffit; P. Monaghan; S. Nanda; K.D. Paschke; C.F. Perdrisat; V. Punjabi; I.A. Qattan; R.D. Ransome; P.E. Reimer; B. Reitz; A. Saha; E.C. Schulte; R. Sheyor; K. Slifer; P. Solvignon; V. Sulkosky; G.M. Urciuoli; E. Voutier; K. Wang; K. Wijesooriya; B. Wojtsekhowski; L. Zhu

    2007-02-26

    We measured the angular dependence of the three recoil proton polarization components in two-body photodisintegration of the deuteron at a photon energy of 2 GeV. These new data provide a benchmark for calculations based on quantum chromodynamics. Two of the five existing models have made predictions of polarization observables. Both explain the longitudinal polarization transfer satisfactorily.. Transverse polarizations are not well described, but suggest isovector dominance.

  13. Transient energy excitation in shortcuts to adiabaticity for the time-dependent harmonic oscillator

    SciTech Connect

    Chen Xi; Muga, J. G.

    2010-11-15

    We study for the time-dependent harmonic oscillator the transient energy excitation in speed-up processes ('shortcuts to adiabaticity') designed to reproduce the initial populations at some predetermined final frequency and time. We provide lower bounds and examples. Implications for the limits imposed to the process times and for the principle of unattainability of the absolute zero, in a single expansion or in quantum refrigerator cycles, are drawn.

  14. Potential of Renewable Energy to Reduce the Dependence of the State of Hawaii on Oil

    SciTech Connect

    Arent, D.; Barnett, J.; Mosey, G.; Wise, A.

    2009-01-01

    Deriving nearly 90% of its primary energy resources from oil, the State of Hawaii is more dependent on oil than any other U.S. state. The price of electricity in Hawaii is also more than twice the U.S. average. The Energy Policy Act of 2005 directed assessment of the economic implications of Hawaii's oil dependence and the feasibility of using renewable energy to help meet the state's electrical generation and transportation fuel use. This paper is based on the assessments and report prepared in response to that directive.Current total installed electrical capacity for the State of Hawaii is 2,414 MWe, 83% of which is fuel-oil generated, but already including about 170 MWe of renewable capacity. The assessments identified about 2,133 MWe (plus another estimated 2,000 MWe of rooftop PV systems) of potential new renewable energy capacity. Most notable, in addition to the rooftop solar potential, is 750 MWe and 140 MWe of geothermal potential on Hawaii and Maui, respectively, 840 MWe of potential wind capacity, primarily on Lanai and Molokai, and one potential 285 MWe capacity specific solar project (PV or solar thermal) identified on Kauai. Important social, political, and electrical-grid infrastructure challenges would need to be overcome to realize this potential. Among multiple crop and acreage scenarios, biofuels assessment found 360,000 acres in Hawaii zoned for agriculture and appropriate for sugarcane, enough to produce 429 million gallons of ethanol-enough to meet about 64% of current 2005 Hawaiian gasoline use. Tropical oil seed crops-potentially grown on the same land-might meet a substantial portion of current diesel use, but there has been little experience growing such crops in Hawaii. The U.S. Department of Energy and the State of Hawaii initiated in January 2008 a program that seeks to reduce Hawaii's oil dependence and provide 70% of the state's primary energy from clean energy sources by 2030. The Hawaii Clean Energy Initiative (HCEI) activities will

  15. Thickness dependent wetting properties and surface free energy of HfO2 thin films

    NASA Astrophysics Data System (ADS)

    Zenkin, Sergei; Belosludtsev, Alexandr; Kos, Šimon; Čerstvý, Radomír; Haviar, Stanislav; Netrvalová, Marie

    2016-06-01

    We show here that intrinsic hydrophobicity of HfO2 thin films can be easily tuned by the variation of film thickness. We used the reactive high-power impulse magnetron sputtering for preparation of high-quality HfO2 films with smooth topography and well-controlled thickness. Results show a strong dependence of wetting properties on the thickness of the film in the range of 50-250 nm due to the dominance of the electrostatic Lifshitz-van der Waals component of the surface free energy. We have found the water droplet contact angle ranging from ≈120° for the thickness of 50 nm to ≈100° for the thickness of 2300 nm. At the same time the surface free energy grows from ≈25 mJ/m2 for the thickness of 50 nm to ≈33 mJ/m2 for the thickness of 2300 nm. We propose two explanations for the observed thickness dependence of the wetting properties: influence of the non-dominant texture and/or non-monotonic size dependence of the particle surface energy.

  16. System size, energy and centrality dependence of strange hadron elliptic flow at STAR

    SciTech Connect

    Masui, Hiroshi

    2008-12-21

    The elliptic flow (v{sub 2}) pattern in terms of hadron mass and transverse momentum p{sub T} is qualitatively described for p{sub T} < 2 GeV/c by ideal hydrodynamics in Au + Au collisions at RHIC. In addition, for p{sub T} = 2-6 GeV/c the measured v{sub 2} follow a universal scaling by the number of quarks explained by quark coalescence/recombination models. These observations suggest that a partonic collectivity develops in the matter in early stage of heavy ion collisions. Centrality as well as system size and energy dependence of the v{sub 2} is important to shed light on the underlying collision dynamics in heavy ion collisions. We present the measurements of centrality dependence of v{sub 2} at {radical}s{sub NN} = 200 and 62.4 GeV in Au + Au and Cu + Cu collisions for K{sub S}{sup 0}, {phi}, {Lambda}, {Xi} and {Omega} at STAR experiment. We focus on the recent Cu + Cu results and discuss the centrality dependence of v{sub 2} as well as the number of quark scaling as a function of transverse kinetic energy at different system size and energies. We also discuss the eccentricity scaled v{sub 2} for identified hadrons and implications that ideal hydrodynamical limit has not been reached at RHIC.

  17. A coarse-grain force field for RDX: Density dependent and energy conserving.

    PubMed

    Moore, Joshua D; Barnes, Brian C; Izvekov, Sergei; Lísal, Martin; Sellers, Michael S; Taylor, DeCarlos E; Brennan, John K

    2016-03-14

    We describe the development of a density-dependent transferable coarse-grain model of crystalline hexahydro-1,3,5-trinitro-s-triazine (RDX) that can be used with the energy conserving dissipative particle dynamics method. The model is an extension of a recently reported one-site model of RDX that was developed by using a force-matching method. The density-dependent forces in that original model are provided through an interpolation scheme that poorly conserves energy. The development of the new model presented in this work first involved a multi-objective procedure to improve the structural and thermodynamic properties of the previous model, followed by the inclusion of the density dependency via a conservative form of the force field that conserves energy. The new model accurately predicts the density, structure, pressure-volume isotherm, bulk modulus, and elastic constants of the RDX crystal at ambient pressure and exhibits transferability to a liquid phase at melt conditions. PMID:26979691

  18. Energy-loss- and thickness-dependent contrast in atomic-scale electron energy-loss spectroscopy

    SciTech Connect

    Tan, Haiyan; Zhu, Ye; Dwyer, Christian; Xin, Huolin L.

    2014-12-31

    Atomic-scale elemental maps of materials acquired by core-loss inelastic electron scattering often exhibit an undesirable sensitivity to the unavoidable elastic scattering, making the maps counter-intuitive to interpret. Here, we present a systematic study that scrutinizes the energy-loss and sample-thickness dependence of atomic-scale elemental maps acquired using 100 keV incident electrons in a scanning transmission electron microscope. For single-crystal silicon, the balance between elastic and inelastic scattering means that maps generated from the near-threshold Si-L signal (energy loss of 99 eV) show no discernible contrast for a thickness of 0.5λ (λ is the electron mean-free path, here approximately 110 nm). At greater thicknesses we observe a counter-intuitive “negative” contrast. Only at much higher energy losses is an intuitive “positive” contrast gradually restored. Our quantitative analysis shows that the energy-loss at which a positive contrast is restored depends linearly on the sample thickness. This behavior is in very good agreement with our double-channeling inelastic scattering calculations. We test a recently-proposed experimental method to correct the core-loss inelastic scattering and restore an intuitive “positive” chemical contrast. The method is demonstrated to be reliable over a large range of energy losses and sample thicknesses. The corrected contrast for near-threshold maps is demonstrated to be (desirably) inversely proportional to sample thickness. As a result, implications for the interpretation of atomic-scale elemental maps are discussed.

  19. Energy-loss- and thickness-dependent contrast in atomic-scale electron energy-loss spectroscopy

    DOE PAGES

    Tan, Haiyan; Zhu, Ye; Dwyer, Christian; Xin, Huolin L.

    2014-12-31

    Atomic-scale elemental maps of materials acquired by core-loss inelastic electron scattering often exhibit an undesirable sensitivity to the unavoidable elastic scattering, making the maps counter-intuitive to interpret. Here, we present a systematic study that scrutinizes the energy-loss and sample-thickness dependence of atomic-scale elemental maps acquired using 100 keV incident electrons in a scanning transmission electron microscope. For single-crystal silicon, the balance between elastic and inelastic scattering means that maps generated from the near-threshold Si-L signal (energy loss of 99 eV) show no discernible contrast for a thickness of 0.5λ (λ is the electron mean-free path, here approximately 110 nm). Atmore » greater thicknesses we observe a counter-intuitive “negative” contrast. Only at much higher energy losses is an intuitive “positive” contrast gradually restored. Our quantitative analysis shows that the energy-loss at which a positive contrast is restored depends linearly on the sample thickness. This behavior is in very good agreement with our double-channeling inelastic scattering calculations. We test a recently-proposed experimental method to correct the core-loss inelastic scattering and restore an intuitive “positive” chemical contrast. The method is demonstrated to be reliable over a large range of energy losses and sample thicknesses. The corrected contrast for near-threshold maps is demonstrated to be (desirably) inversely proportional to sample thickness. As a result, implications for the interpretation of atomic-scale elemental maps are discussed.« less

  20. Does EU's energy dependence on Russia increase price volatility for consumers?

    NASA Astrophysics Data System (ADS)

    Yekeler, Zeynep

    Europe's dependence on natural gas imports from Russia has raised questions about energy risk and the vulnerability of the European countries, especially after the supply cuts in 2006, 2008, 2009, and 2012. The implementation of the Third Energy Package to finally unify European energy markets by linking the states located on the periphery to the well connected gas hubs in Northern Europe has been slow due to a lack of political will across Europe. This has enabled Russian Gazprom to retain its position as a major player in European markets and hinder any European effort to diversify the energy portfolio of the region. Using residential natural gas and electricity price data from 2000 through 2014, this paper analyzes the impact of EU's import reliance on natural gas from Russia and the supply disruptions on the volatility of natural gas and electricity prices through a fixed effects regression model. Results indicate that while the size of Russian natural gas imports does not significantly affect natural gas and electricity price volatility in EU countries, security supply measures such as natural gas stocks matter, especially for Southeast European countries that consistently pay more according to the results. The paper concludes by discussing the importance of formulating policies that not only aim to reduce overall EU dependence but minimize Southeastern Europe's vulnerabilities. Policy suggestions include increasing cross-border interconnectors and storage capacity as well as increasing LNG import capacity by building regasification terminals in periphery countries like Greece, Bulgaria, Romania and Slovenia.

  1. Thermodynamics predicts density-dependent energy use in organisms and ecological communities.

    PubMed

    Yen, Jian D L; Paganin, David M; Thomson, James R; Mac Nally, Ralph

    2015-04-01

    Linking our knowledge of organisms to our knowledge of ecological communities and ecosystems is a key challenge for ecology. Individual size distributions (ISDs) link the size of individual organisms to the structure of ecological communities, so that studying ISDs might provide insight into how organism functioning affects ecosystems. Similarly shaped ISDs among ecosystems, coupled with allometric links between organism size and resource use, suggest the possibility of emergent resource-use patterns in ecological communities. We drew on thermodynamics to develop a maximization principle that predicted both organism and community energy use. These predictions highlighted the importance of density-dependent metabolic rates and were able to explain nonlinear relationships between community energy use and community biomass. We analyzed data on fish community energy use and biomass and found evidence of nonlinear scaling, which was predicted by the thermodynamic principle developed here and is not explained by other theories of ISDs. Detailed measurements of organism energy use will clarify the role of density dependence in driving metabolic rates and will further test our derived thermodynamic principle. Importantly, our study highlights the potential for fundamental links between ecology and thermodynamics.

  2. Thermal effects on nuclear symmetry energy with a momentum-dependent effective interaction

    SciTech Connect

    Moustakidis, Ch. C.

    2007-08-15

    The knowledge of the nuclear symmetry energy of hot neutron-rich matter is important for understanding the dynamical evolution of massive stars and the supernova explosion mechanisms. In particular, the electron capture rate on nuclei and/or free protons in presupernova explosions is especially sensitive to the symmetry energy at finite temperature. In view of the above, in the present work we calculate the symmetry energy as a function of the temperature for various values of the baryon density by applying a momentum-dependent effective interaction. In addition to a previous work, the thermal effects are studied separately both in the kinetic part and the interaction part of the symmetry energy. We focus also on the calculations of the mean-field potential, employed extensively in heavy-ion reaction research, both for nuclear and pure neutron matter. The proton fraction and the electron chemical potential, which are crucial quantities for representing the thermal evolution of supernova and neutron stars, are calculated for various values of the temperature. Finally, we construct a temperature dependent equation of state of {beta}-stable nuclear matter, the basic ingredient for the evaluation of the neutron star properties.

  3. The Z dependence of the total energy, energy components, orbital energy, and MO coefficients for mononuclear, isoelectronic species

    NASA Astrophysics Data System (ADS)

    Murdoch, Joseph R.; Magnoli, Douglas E.

    1982-11-01

    Previous workers have shown that in the limit Z→∞, the total energies, Vne, T, and total orbital energies (E0) of a series of isoelectronic, mononuclear structures are quadratic functions of Z, while Vee is a linear function of Z. In the present paper, a new perturbational treatment is presented which is based on a zero-order solution corresponding to Z=Z0, where Z0 is arbitrary. For first-order corrections to Hartree-Fock wave functions, the same limiting behavior (E,Vne, T, E0≡quadratic functions of Z; Vee≡linear function of Z) is seen as for the high-Z limit (Z→∞). For higher-order corrections, a completely different pattern of behavior emerges. For the ten-electron series (Z=9,18), E and T remain highly quadratic with respect to Z (to within 7 kcal), but Vne, Vee, E 0 exhibit large oscillations (˜60 kcal) around a quadratic function. This behavior is analyzed by applying the virial and Hellmann-Feynman theorems to the total energy, the Hellmann-Feynman theorem to Hartree-Fock orbital energies, and by expressing perturbation expansions for Vne and E in terms of Cheybshev polynomials. The results provide a demonstration of the fact that the total energy and orbital energy may show a different pattern of behavior with respect to substituent effects. The present work has important implications for perturbational treatments, such as Walsh's rules, frontier orbital theory and orbital symmetry correlations, which are based on the behavior of the orbital energy rather than the total energy.

  4. Energy Dependence of Synchrotron X-Ray Rims in Tycho's Supernova Remnant

    NASA Technical Reports Server (NTRS)

    Tran, Aaron; Williams, Brian J.; Petre, Robert; Ressler, Sean M.; Reynolds, Stephen P.

    2015-01-01

    Several young supernova remnants exhibit thin X-ray bright rims of synchrotron radiation at their forward shocks. Thin rims require strong magnetic field amplification beyond simple shock compression if rim widths are only limited by electron energy losses. But, magnetic field damping behind the shock could produce similarly thin rims with less extreme field amplification. Variation of rim width with energy may thus discriminate between competing influences on rim widths. We measured rim widths around Tycho's supernova remnant in 5 energy bands using an archival 750 ks Chandra observation. Rims narrow with increasing energy and are well described by either loss-limited or damped scenarios, so X-ray rim width-energy dependence does not uniquely specify a model. But, radio counterparts to thin rims are not loss-limited and better reflect magnetic field structure. Joint radio and X-ray modeling favors magnetic damping in Tycho's SNR with damping lengths approximately 1-5% of remnant radius and magnetic field strengths approximately 50-400 micron G assuming Bohm diffusion. X-ray rim widths are approximately 1% of remnant radius, somewhat smaller than inferred damping lengths. Electron energy losses are important in all models of X-ray rims, suggesting that the distinction between loss-limited and damped models is blurred in soft X-rays. All loss-limited and damping models require magnetic fields approximately greater than 20 micron G, arming the necessity of magnetic field amplification beyond simple compression.

  5. Latitude and local time dependence of precipitated low energy electrons at high latitudes

    NASA Technical Reports Server (NTRS)

    Gustafsson, G.

    1972-01-01

    Data from particle detectors on board the satellite OGO-4 were used to study the precipitation of electrons in the energy range 0.7 to 24 keV. The latitude dependence of these particles in the local time region from midnight to dawn was investigated in detail. The analysis shows that the precipitation of particles of energies 2.3 to 24 keV is centered at an invariant latitude of about 68 deg at midnight with a clear shift in latitude with increasing local time and this shift is more pronounced for lower energies. The highest fluxes of particles in this energy interval are measured at midnight and they decrease rapidly with local time. The data in the energy range 2.3 to 24 keV support a theory where particles are injected in the midnight region from the tail gaining energy due to a betatron process and then drift eastwards in a combined electric and magnetic field. The main part of the electrons at 0.7 keV show a different behavior. They seem to undergo an acceleration process which is rather local, sometimes giving field aligned fluxes which may be super-imposed on the background precipitation.

  6. ENERGY DEPENDENCE OF SYNCHROTRON X-RAY RIMS IN TYCHO’S SUPERNOVA REMNANT

    SciTech Connect

    Tran, Aaron; Williams, Brian J.; Petre, Robert; Reynolds, Stephen P.

    2015-10-20

    Several young supernova remnants (SNRs) exhibit thin X-ray bright rims of synchrotron radiation at their forward shocks. Thin rims require strong magnetic field amplification beyond simple shock compression if rim widths are only limited by electron energy losses. But, magnetic field damping behind the shock could produce similarly thin rims with less extreme field amplification. Variation of rim width with energy may thus discriminate between competing influences on rim widths. We measured rim widths around Tycho's SNR in five energy bands using an archival 750 ks Chandra observation. Rims narrow with increasing energy and are well described by either loss-limited or damped scenarios, so X-ray rim width-energy dependence does not uniquely specify a model. But, radio counterparts to thin rims are not loss-limited and better reflect magnetic field structure. Joint radio and X-ray modeling favors magnetic damping in Tycho's SNR with damping lengths ∼1%–5% of remnant radius and magnetic field strengths ∼50–400 μG assuming Bohm diffusion. X-ray rim widths are ∼1% of remnant radius, somewhat smaller than inferred damping lengths. Electron energy losses are important in all models of X-ray rims, suggesting that the distinction between loss-limited and damped models is blurred in soft X-rays. All loss-limited and damping models require magnetic fields ≳20 μG, affirming the necessity of magnetic field amplification beyond simple compression.

  7. Dependence of solid-liquid interface free energy on liquid structure

    SciTech Connect

    Wilson, S R; Mendelev, M I

    2014-09-01

    The Turnbull relation is widely believed to enable prediction of solid–liquid interface (SLI) free energies from measurements of the latent heat and the solid density. Ewing proposed an additional contribution to the SLI free energy to account for variations in liquid structure near the interface. In the present study, molecular dynamics (MD) simulations were performed to investigate whether SLI free energy depends on liquid structure. Analysis of the MD simulation data for 11 fcc metals demonstrated that the Turnbull relation is only a rough approximation for highly ordered liquids, whereas much better agreement is observed with Ewing’s theory. A modification to Ewing’s relation is proposed in this study that was found to provide excellent agreement with MD simulation data.

  8. Isospin effects and the density dependence of the nuclear symmetry energy

    SciTech Connect

    Souza, S. R.; Tsang, M. B.; Lynch, W. G.; Steiner, A. W.; Carlson, B. V.; Donangelo, R.

    2009-10-15

    The density dependence of the nuclear symmetry energy is inspected using the statistical multifragmentation model with Skyrme effective interactions. The model consistently considers the expansion of the fragments' volumes at finite temperature at the freeze-out stage. By selecting parametrizations of the Skyrme force that lead to very different equations of state for the symmetry energy, we investigate the sensitivity of the isoscaling parameter and the isotopic distributions to differences in the symmetry energy. Our results suggest that, in spite of being sensitive to the thermal dilation of the fragments' volumes, it is difficult to distinguish among the Skyrme forces from the isoscaling analysis. On the other hand, the isotopic distribution of the emitted fragments turns out to be very sensitive to the force employed in the calculation.

  9. A FLUORESCENCE PROBE OF ENERGY-DEPENDENT STRUCTURE CHANGES IN FRAGMENTED MEMBRANES*

    PubMed Central

    Azzi, A.; Chance, B.; Radda, G. K.; Lee, C. P.

    1969-01-01

    The reaction of the fluorochrome, 8-anilino-1-naphthalene-sulfonic acid (ANS), with fragmented membranes from beef heart mitochondria has been studied. ANS fluorescence is found to be enhanced 25-fold on binding to the membrane fragments in the absence of energy conservation, and this enhancement is increased to 35-fold in the membrane energized by substrate plux oxygen. The fluorescence of bound ANS depends upon the energy state of the membrane fragments, as indicated by the effects of ATP, substrates of the respiratory chain, oligomycin, and uncouplers. It is concluded that the changes of ANS fluorescence indicate structural changes of the mitochondrial membrane associated with energy conservation. The time course of energization is readily followed by ANS, and has a half-time of two seconds at 26°. PMID:4307717

  10. Nanocluster ionization energies and work function of aluminum, and their temperature dependence

    SciTech Connect

    Halder, Avik; Kresin, Vitaly V.

    2015-10-28

    Ionization threshold energies of Al{sub n} (n = 32-95) nanoclusters are determined by laser ionization of free neutral metal clusters thermalized to several temperatures in the range from 65 K to 230 K. The photoion yield curves of cold clusters follow a quadratic energy dependence above threshold, in agreement with the Fowler law of surface photoemission. Accurate data collection and analysis procedures make it possible to resolve very small (few parts in a thousand) temperature-induced shifts in the ionization energies. Extrapolation of the data to the bulk limit enables a determination of the thermal shift of the polycrystalline metal work function, found to be in excellent agreement with theoretical prediction based on the influence of thermal expansion. Small clusters display somewhat larger thermal shifts, reflecting their greater susceptibility to thermal expansion. Ionization studies of free size-resolved nanoclusters facilitate understanding of the interplay of surface, electronic, and lattice properties under contamination-free conditions.

  11. Size-dependent adhesion energy of shape-selected Pd and Pt nanoparticles

    NASA Astrophysics Data System (ADS)

    Ahmadi, M.; Behafarid, F.; Cuenya, B. Roldan

    2016-06-01

    Thermodynamically stable shape-selected Pt and Pd nanoparticles (NPs) were synthesized via inverse micelle encapsulation and a subsequent thermal treatment in vacuum above 1000 °C. The majority of the Pd NPs imaged via scanning tunneling microscopy (STM) had a truncated octahedron shape with (111) top and interfacial facets, while the Pt NPs were found to adopt a variety of shapes. For NPs of identical shape for both material systems, the NP-support adhesion energy calculated based on STM data was found to be size-dependent, with large NPs (e.g. ~6 nm) having lower adhesion energies than smaller NPs (e.g. ~1 nm). This phenomenon was rationalized based on support-induced strain that for larger NPs favors the formation of lattice dislocations at the interface rather than a lattice distortion that may propagate through the smaller NPs. In addition, identically prepared Pt NPs of the same shape were found to display a lower adhesion energy compared to Pd NPs. While in both cases, a transition from a lattice distortion to interface dislocations is expected to occur with increasing NP size, the higher elastic energy in Pt leads to a lower transition size, which in turn lowers the adhesion energy of Pt NPs compared to Pd.Thermodynamically stable shape-selected Pt and Pd nanoparticles (NPs) were synthesized via inverse micelle encapsulation and a subsequent thermal treatment in vacuum above 1000 °C. The majority of the Pd NPs imaged via scanning tunneling microscopy (STM) had a truncated octahedron shape with (111) top and interfacial facets, while the Pt NPs were found to adopt a variety of shapes. For NPs of identical shape for both material systems, the NP-support adhesion energy calculated based on STM data was found to be size-dependent, with large NPs (e.g. ~6 nm) having lower adhesion energies than smaller NPs (e.g. ~1 nm). This phenomenon was rationalized based on support-induced strain that for larger NPs favors the formation of lattice dislocations at the

  12. Simulating Time-Dependent Energy Transfer Between Crossed Laser Beams in an Expanding Plasma

    SciTech Connect

    Hittinger, J F; Dorr, M R; Berger, R L; Williams, E A

    2004-10-11

    A coupled mode system is derived to investigate a three-wave parametric instability leading to energy transfer between co-propagating laser beams crossing in a plasma flow. The model includes beams of finite width refracting in a prescribed transverse plasma flow with spatial and temporal gradients in velocity and density. The resulting paraxial light equations are discretized spatially with a Crank-Nicholson-type scheme, and these algebraic constraints are nonlinearly coupled with ordinary differential equations in time that describe the ion acoustic response. The entire nonlinear differential-algebraic system is solved using an adaptive, backward-differencing method coupled with Newton's method. A numerical study is conducted in two dimensions that compares the intensity gain of the fully time-dependent coupled mode system with the gain computed under the further assumption of a strongly-damped ion acoustic response. The results demonstrate a time-dependent gain suppression when the beam diameter is commensurate with the velocity gradient scale length. The gain suppression is shown to depend on time-dependent beam refraction and is interpreted as a time-dependent frequency shift.

  13. On the energy-dependence of Hoechst 33342 transport by the ABC transporter LmrA.

    PubMed

    Venter, Henrietta; Velamakanni, Saroj; Balakrishnan, Lekshmy; van Veen, Hendrik W

    2008-02-15

    LmrA is an ATP-binding cassette (ABC) multidrug transporter from Lactococcus lactis, and is a structural homologue of the human multidrug resistance P-glycoprotein (ABCB1), the overexpression of which is associated with multidrug resistance in tumours. We recently observed that a truncated version of LmrA lacking the nucleotide-binding domain mediates a proton motive force-dependent ethidium transport reaction by catalyzing proton-ethidium symport. This finding raised the question whether proton motive force-dependent transport can also be observed for other drugs, and whether this reaction is also relevant for full-length LmrA. Furthermore, the observations on LmrA-MD raised the question whether ATP-dependent transport by LmrA in intact cells could be due to the activity of independent ABC transporters that might become upregulated in the lactococcal cells due to the overexpression of LmrA; the recently identified ABC multidrug transporter LmrCD was put forward as a possible candidate. Here, we investigated the energy coupling to the transport of the amphiphilic dye Hoechst 33342 in proteoliposomes containing purified LmrA. For this purpose, LmrA was obtained from lactococcal cells lacking the genomic lmrA and lmrCD genes, in which LmrA was expressed from a plasmid. To separate ATP-dependence from proton motive force-dependence, we also used mutant LmrA proteins, which were affected in their ability to hydrolyse ATP. Our studies in proteoliposomes demonstrate that LmrA can catalyze Hoechst 33342 transport independent of auxiliary proteins, in an ATP-dependent fashion and a transmembrane chemical proton gradient (interior acidic)-dependent fashion.

  14. Resolving the energy and temperature dependence of C6H6 (∗) collisional relaxation via time-dependent bath temperature measurements.

    PubMed

    West, Niclas A; Winner, Joshua D; Bowersox, Rodney D W; North, Simon W

    2016-07-01

    The relaxation of highly vibrationally excited benzene, generated by 193 nm laser excitation, was studied using the transient rotational-translational temperature rise of the N2 bath, which was measured by proxy using two-line laser induced fluorescence of seeded NO. The resulting experimentally measured time-dependent N2 temperature rises were modeled with MultiWell based simulations of Collisional Energy Transfer (CET) from benzene vibration to N2 rotation-translation. We find that the average energy transferred in benzene deactivating collisions depends linearly on the internal energy of the excited benzene molecules and depends approximately linearly on the N2 bath temperature between 300 K and 600 K. The results are consistent with experimental studies and classical trajectory calculations of CET in similar systems. PMID:27394109

  15. Resolving the energy and temperature dependence of C6H6∗ collisional relaxation via time-dependent bath temperature measurements

    NASA Astrophysics Data System (ADS)

    West, Niclas A.; Winner, Joshua D.; Bowersox, Rodney D. W.; North, Simon W.

    2016-07-01

    The relaxation of highly vibrationally excited benzene, generated by 193 nm laser excitation, was studied using the transient rotational-translational temperature rise of the N2 bath, which was measured by proxy using two-line laser induced fluorescence of seeded NO. The resulting experimentally measured time-dependent N2 temperature rises were modeled with MultiWell based simulations of Collisional Energy Transfer (CET) from benzene vibration to N2 rotation-translation. We find that the average energy transferred in benzene deactivating collisions depends linearly on the internal energy of the excited benzene molecules and depends approximately linearly on the N2 bath temperature between 300 K and 600 K. The results are consistent with experimental studies and classical trajectory calculations of CET in similar systems.

  16. Scatttering of High-energy Particles at a Collisionless Shock Front: Dependence on the Shock Angle

    NASA Astrophysics Data System (ADS)

    Gedalin, M.; Dröge, W.; Kartavykh, Y. Y.

    2015-07-01

    Many shock acceleration theories deal with gyrophase-averaged particle distributions that depend only on the energy and pitch angle of the particles. Diffusive shock acceleration includes shock crossing as a necessary component. As long as the shock width is much smaller than the mean free path of a particle, the crossing is governed by the macroscopic fields inside the transition layer. The dynamics of high-energy particles in these fields is non-adiabatic and gyrophase dependent. The magnetic moment is not conserved in a wide range of shock angles, nor is the condition of reflection determined by the magnetic bottle relation. Instead, for a pitch angle and unknown gyrophase of an incident particle there is a finite probability of reflection. This probability varies between zero and unity in a wide range of pitch angles. In this work we investigate how the matching conditions at the shock front could be modified with the gyrophase dependence taken into account, e.g., in the form of the scattering probabilities.

  17. Energy and Mass-Number Dependence of Hadron-Nucleus Total Reaction Cross Sections

    NASA Astrophysics Data System (ADS)

    Kohama, Akihisa; Iida, Kei; Oyamatsu, Kazuhiro

    2016-09-01

    We thoroughly investigate how proton-nucleus total reaction cross sections depend on the target mass number A and the proton incident energy. In doing so, we systematically analyze nuclear reaction data that are sensitive to nuclear size, namely, proton-nucleus total reaction cross sections and differential elastic cross sections, using a phenomenological black-sphere approximation of nuclei that we are developing. In this framework, the radius of the black sphere is found to be a useful length scale that simultaneously accounts for the observed proton-nucleus total reaction cross section and first diffraction peak in the proton elastic differential cross section. This framework, which is shown here to be applicable to antiprotons, is expected to be applicable to any kind of projectile that is strongly attenuated in the nucleus. On the basis of a cross-section formula constructed within this framework, we find that a less familiar A1/6 dependence plays a crucial role in describing the energy dependence of proton-nucleus total reaction cross sections.

  18. Incident-energy-dependent spectral weight of resonant inelastic x-ray scattering in doped cuprates

    NASA Astrophysics Data System (ADS)

    Tsutsui, Kenji; Tohyama, Takami

    2016-08-01

    We theoretically investigate the incident-photon energy ωi dependence of resonant inelastic x-ray scattering (RIXS) tuned for the Cu L edge in cuprate superconductors by using the exact diagonalization technique for a single-band Hubbard model. Depending on the value of core-hole Coulomb interaction in the intermediate state, RIXS for non-spin-flip channel shows either a ωi-dependent fluorescencelike or ωi-independent Raman-like behavior for hole doping. An analysis of x-ray absorption suggests that the core-hole Coulomb interaction is larger than on-site Coulomb interaction in the Hubbard model, resulting in a fluorescencelike behavior in RIXS consistent with recent RIXS experiments. A shift on the high-energy side of the center of spectral distribution is also predicted for electron-doped systems though spectral weight is small. Main structures in the spin-flip channel exhibit a Raman-like behavior as expected, accompanied with a fluorescencelike behavior with small intensity.

  19. SCATTTERING OF HIGH-ENERGY PARTICLES AT A COLLISIONLESS SHOCK FRONT: DEPENDENCE ON THE SHOCK ANGLE

    SciTech Connect

    Gedalin, M.; Dröge, W.; Kartavykh, Y. Y.

    2015-07-10

    Many shock acceleration theories deal with gyrophase-averaged particle distributions that depend only on the energy and pitch angle of the particles. Diffusive shock acceleration includes shock crossing as a necessary component. As long as the shock width is much smaller than the mean free path of a particle, the crossing is governed by the macroscopic fields inside the transition layer. The dynamics of high-energy particles in these fields is non-adiabatic and gyrophase dependent. The magnetic moment is not conserved in a wide range of shock angles, nor is the condition of reflection determined by the magnetic bottle relation. Instead, for a pitch angle and unknown gyrophase of an incident particle there is a finite probability of reflection. This probability varies between zero and unity in a wide range of pitch angles. In this work we investigate how the matching conditions at the shock front could be modified with the gyrophase dependence taken into account, e.g., in the form of the scattering probabilities.

  20. Temperature dependence of antenna excitation transport in native photosystem I particles. [Electronic energy transport (EET)

    SciTech Connect

    Lyle, P.A.; Struve, W.S. )

    1991-05-16

    The temperature dependence of polarized photobleaching dynamics was investigated through 680-nm pump-probe experiments in the Chl a antenna of native photosystem 1 particles (Chl/P700 {approximately} 200) from spinach. The anisotropic decay time is lengthened by an order of magnitude (from {approximately}7 to {approximately}62 ps) when the temperature is reduced from 290 to 38 K; most of this increase occurs between 65 and 38 K. The occurrence of this transition temperature in the tens of kelvin reflects the participation of protein phonons in antenna EET. The isotopic decay kinetics are considerably less temperature sensitive, indicating that the anisotropic and isotropic decays stem from different energy-transfer processes with contrasting temperature dependence. The 38 K photobleaching spectrum at 5 ps exhibits considerably more weighting in the lower energy Chl a spectral forms than the room-temperature spectrum, suggesting that rapid spectral equilibration occurs in the photosystem 1 antenna. In light of the phonon frequency and electron-phonon coupling parameters determined in independent PSI-200 spectral hole-burning experiments, the quantitative temperature dependence int he anisotropic decay times is consistent with a theory for phonon-assisted EET in which the pertinent phonons are independent modes localized about the donor and acceptor chromophores.

  1. Electron energy dependence of amorphization in Zr{sub 3}Fe

    SciTech Connect

    Motta, A.T.; Howe, L.M.; Okamoto, P.R.

    1994-02-01

    This paper reports the results from a study conducted to determine the effect of electron energy on the dose-to-amorphization of Zr{sub 3,}Fe at 23--30 K. Zr{sub 3}Fe samples were irradiated in the HVEM at Argonne National Laboratory, at 200 to 900 keV. Amorphization occurred at electron energies from 900 keV down to 250 keV. Three distinct regions were observed: between 900 and 700 key amorphization occurred at a constant low dose of {approximately} 4 {times} 10{sup 21} e cm{sup {minus}2}; a higher plateau at 10{sup 22} was observed between 600 and 400 keV, and finally there was a sharp increase in the dose-to-amorphization below 400 key, so that at 250 key the necessary dose was an order of magnitude higher than that at 900 keV. In the region below 400 keV there was evidence of a dependence of the dose-to-amorphization on the orientation of the sample with respect to the electron beam. The results can be analyzed in terms of a composite displacement cross section dominated at high energies by displacements of Zr and Fe atoms, by displacements of Fe atoms at intermediate energies and of secondary displacements of lattice atoms by recoil impurities at low energies.

  2. The Local Plasma Frequency Approach in Description of the Impact-Parameter Dependence of Energy Loss

    NASA Astrophysics Data System (ADS)

    Khodyrev, V. A.

    The LPF approach of Lindhard and Scharff is generalized to describe on the same basis the impact parameter dependence of energy loss in ion-atom collision. To make this feasible the energy loss is represented as an integral of the local energy deposition over the atomic shell volume. The local energy loss is determined by the induced electron current and the intensity of the projectile field at a given point. The LPF approach consists in an approximate description of the induced current using the corresponding expression for a uniform electron gas. With an appropriate description of the electron gas response, the atomic shell polarization and the state of electron motion are considered. The developed approach provides a possibility to test the accuracy of the customary approximation where the energy loss is expressed through the electron density on the ion trajectory, the local density approximation. A comparison with the available experimental results displays the adequateness of the developed approach if, additionally, the higher-order corrections over the projectile charge are taken into account.

  3. Energy and frequency dependence of the alpha particle redistribution produced by internal kink modes

    SciTech Connect

    Farengo, R.; Ferrari, H. E.; Garcia-Martinez, P. L.; Firpo, M.-C.; Ettoumi, W.; Lifschitz, A. F.

    2014-08-15

    The redistribution of alpha particles due to internal kink modes is studied. The exact particle trajectories in the total fields, equilibrium plus perturbation, are calculated. The equilibrium has circular cross section and the plasma parameters are similar to those expected in ITER. The alpha particles are initially distributed according to a slowing down distribution function and have energies between 18 keV and 3.5 MeV. The (1, 1), (2, 2), and (2, 1) modes are included and the effect of changing their amplitude and frequency is studied. When only the (1, 1) mode is included, the spreading of high energy (E≳1 MeV) alpha particles increases slowly with the energy and mode frequency. At lower energies, the redistribution is more sensitive to the mode frequency and particle energy. When a (2, 1) mode is added, the spreading increases significantly and particles can reach the edge of the plasma. Trapped particles are the most affected and the redistribution parameter can have maxima above 1 MeV, depending on the mode frequency. These results can have important implications for ash removal.

  4. Field-dependent energy barriers in Co/CoO core-shell nanoparticles

    NASA Astrophysics Data System (ADS)

    Nieves, P.; Kechrakos, D.; Chubykalo-Fesenko, O.

    2016-02-01

    We perform atomistic modeling of Co/CoO nanoparticles with a diameter of a few nanometers and realistic values of the exchange and anisotropy parameters in order to study the field-dependent energy barriers under forward and backward reversal of the magnetization. The barriers are extracted from the constrained energy minimization using the integration of the Landau-Lifshitz-Gilbert equations and the Lagrange multiplier method. We show that the applied field and the interface exchange strength have opposite effects on the values of the energy barriers. In particular, while the backward (forward) energy barrier increases (decreases) linearly with the strength of the interface exchange coupling, it decreases (increases) almost quadratically with the applied magnetic field. Our results are in good agreement with the well-known Meiklejohn-Bean model of exchange bias, and allow us to analyze the limits of applicability of the macrospin approach to the study of energy barriers in core-shell Co/CoO nanoparticles.

  5. Results on the energy dependence of cosmic-ray charge composition

    NASA Technical Reports Server (NTRS)

    Balasubrahmanyan, V. K.; Ormes, J. F.

    1973-01-01

    Results of measurements by a balloon-borne ionization spectrometer of the energy dependence of high-energy cosmic-ray charge composition. The results presented are greatly improved over those obtained earlier by Ormes et al. (1971) by the use of a multidimensional charge analysis with more efficient background rejection, and a more accurate energy determination. Complex couplings between the charge, energy, and trajectory information were taken into account and are discussed. The spectra of individual elements up to oxygen and of groups of nuclei up through iron were measured up to almost 100 GeV per nucleon. The energy spectrum of the secondary nuclei, B + N, is found to be steeper than that of the primary nuclei, C + O, in agreement with Smith et al. (1973). The most dramatic finding is that the spectrum of the iron nuclei is flatter than that of the carbon and oxygen nuclei by 0.57 plus or minus 0.14 of a power.

  6. Linking Neuromodulated Spike-Timing Dependent Plasticity with the Free-Energy Principle.

    PubMed

    Isomura, Takuya; Sakai, Koji; Kotani, Kiyoshi; Jimbo, Yasuhiko

    2016-09-01

    The free-energy principle is a candidate unified theory for learning and memory in the brain that predicts that neurons, synapses, and neuromodulators work in a manner that minimizes free energy. However, electrophysiological data elucidating the neural and synaptic bases for this theory are lacking. Here, we propose a novel theory bridging the information-theoretical principle with the biological phenomenon of spike-timing dependent plasticity (STDP) regulated by neuromodulators, which we term mSTDP. We propose that by integrating an mSTDP equation, we can obtain a form of Friston's free energy (an information-theoretical function). Then we analytically and numerically show that dopamine (DA) and noradrenaline (NA) influence the accuracy of a principal component analysis (PCA) performed using the mSTDP algorithm. From the perspective of free-energy minimization, these neuromodulatory changes alter the relative weighting or precision of accuracy and prior terms, which induces a switch from pattern completion to separation. These results are consistent with electrophysiological findings and validate the free-energy principle and mSTDP. Moreover, our scheme can potentially be applied in computational psychiatry to build models of the faulty neural networks that underlie the positive symptoms of schizophrenia, which involve abnormal DA levels, as well as models of the NA contribution to memory triage and posttraumatic stress disorder. PMID:27391680

  7. Measurement of the energy dependence of X-ray-induced decomposition of potassium chlorate.

    PubMed

    Pravica, Michael; Bai, Ligang; Sneed, Daniel; Park, Changyong

    2013-03-21

    We report the first measurements of the X-ray induced decomposition of KClO3 as a function of energy in two experiments. KClO3 was pressurized to 3.5 GPa and irradiated with monochromatic synchrotron X-rays ranging in energy from 15 to 35 keV in 5 keV increments. A systematic increase in the decomposition rate as the energy was decreased was observed, which agrees with the 1/E(3) trend for the photoelectric process, except at the lowest energy studied. A second experiment was performed to access lower energies (10 and 12 keV) using a beryllium gasket; suggesting an apparent resonance near 15 keV or 0.83 Ǻ maximizing the chemical decomposition rate. A third experiment was performed using KIO3 to ascertain the anionic dependence of the decomposition rate, which was observed to be far slower than in KClO3, suggesting that the O-O distance is the critical factor in chemical reactions. These results will be important for more efficiently initiating chemical decomposition in materials using selected X-ray wavelengths that maximize decomposition to aid useful hard X-ray-induced chemistry and contribute understanding of the mechanism of X-ray-induced decomposition of the chlorates.

  8. Linking Neuromodulated Spike-Timing Dependent Plasticity with the Free-Energy Principle.

    PubMed

    Isomura, Takuya; Sakai, Koji; Kotani, Kiyoshi; Jimbo, Yasuhiko

    2016-09-01

    The free-energy principle is a candidate unified theory for learning and memory in the brain that predicts that neurons, synapses, and neuromodulators work in a manner that minimizes free energy. However, electrophysiological data elucidating the neural and synaptic bases for this theory are lacking. Here, we propose a novel theory bridging the information-theoretical principle with the biological phenomenon of spike-timing dependent plasticity (STDP) regulated by neuromodulators, which we term mSTDP. We propose that by integrating an mSTDP equation, we can obtain a form of Friston's free energy (an information-theoretical function). Then we analytically and numerically show that dopamine (DA) and noradrenaline (NA) influence the accuracy of a principal component analysis (PCA) performed using the mSTDP algorithm. From the perspective of free-energy minimization, these neuromodulatory changes alter the relative weighting or precision of accuracy and prior terms, which induces a switch from pattern completion to separation. These results are consistent with electrophysiological findings and validate the free-energy principle and mSTDP. Moreover, our scheme can potentially be applied in computational psychiatry to build models of the faulty neural networks that underlie the positive symptoms of schizophrenia, which involve abnormal DA levels, as well as models of the NA contribution to memory triage and posttraumatic stress disorder.

  9. Beam energy dependence of pseudorapidity distributions of charged particles produced in relativistic heavy-ion collisions

    NASA Astrophysics Data System (ADS)

    Basu, Sumit; Nayak, Tapan K.; Datta, Kaustuv

    2016-06-01

    Heavy-ion collisions at the Relativistic Heavy Ion Collider at Brookhaven National Laboratory and the Large Hadron Collider at CERN probe matter at extreme conditions of temperature and energy density. Most of the global properties of the collisions can be extracted from the measurements of charged-particle multiplicity and pseudorapidity (η ) distributions. We have shown that the available experimental data on beam energy and centrality dependence of η distributions in heavy-ion (Au +Au or Pb +Pb ) collisions from √{sNN}=7.7 GeV to 2.76 TeV are reasonably well described by the AMPT model, which is used for further exploration. The nature of the η distributions has been described by a double Gaussian function using a set of fit parameters, which exhibit a regular pattern as a function of beam energy. By extrapolating the parameters to a higher energy of √{sNN}=5.02 TeV, we have obtained the charged-particle multiplicity densities, η distributions, and energy densities for various centralities. Incidentally, these results match well with some of the recently published data by the ALICE Collaboration.

  10. Sensitivity of de-excitation energies of superdeformed secondary minima to the density dependence of symmetry energy with the relativistic mean-field theory

    NASA Astrophysics Data System (ADS)

    Jiang, W. Z.; Ren, Z. Z.; Sheng, Z. Q.; Zhu, Z. Y.

    2010-06-01

    The relationship between de-excitation energies of superdeformed secondary minima relative to ground states and the density dependence of the symmetry energy is investigated for heavy nuclei using the relativistic mean-field (RMF) model. It is shown that the de-excitation energies of superdeformed secondary minima are sensitive to differences in the symmetry energy that are mimicked by the isoscalar-isovector coupling included in the model. With deliberate investigations on a few Hg isotopes that have data of de-excitation energies, we find that the description for the de-excitation energies can be improved due to the softening of the symmetry energy. Further, we have investigated de-excitation energies of odd-odd heavy nuclei that are nearly independent of pairing correlations, and have discussed the possible extraction of the constraint on the density dependence of the symmetry energy with the measurement of de-excitation energies of these nuclei.

  11. Sub-barrier fusion excitation function data and energy dependent Woods-Saxon potential

    NASA Astrophysics Data System (ADS)

    Gautam, Manjeet Singh

    2016-07-01

    This paper analyzed the role of intrinsic degrees of freedom of colliding nuclei in the enhancement of sub-barrier fusion cross-section data of various heavy ion fusion reactions. The influences of inelastic surface vibrations of colliding pairs are found to be dominant and their couplings result in the significantly larger fusion enhancement over the predictions of the one dimensional barrier penetration model at sub-barrier energies. The theoretical calculations are performed by using energy dependent Woods-Saxon potential model (EDWSP model) in conjunction with the one dimensional Wong formula. The effects of dominant intrinsic channels are entertained within framework of the coupled channel calculations obtained by using the code CCFULL. It is quite interesting to note that the energy dependence in Woods-Saxon potential simulates the effects of inelastic surface vibrational states of reactants wherein significantly larger value of diffuseness parameter ranging from a = 0.85 fm to a = 0.95 fm is required to address the observed fusion excitation function data of the various heavy ion fusion reactions.

  12. Nonlinear ionization mechanism dependence of energy absorption in diamond under femtosecond laser irradiation

    SciTech Connect

    Wang Cong; Jiang Lan; Li Xin; Wang Feng; Yuan Yanping; Lu Yongfeng

    2013-04-14

    We present first-principles calculations for nonlinear photoionization of diamond induced by the intense femtosecond laser field. A real-time and real-space time-dependent density functional theory with the adiabatic local-density approximation is applied to describe the laser-material interactions in the Kohn-Sham formalism with the self-interaction correction. For a certain laser wavelength, the intensity dependence of energy absorption on multiphoton and/or tunnel ionization mechanisms is investigated, where laser intensity regions vary from 10{sup 12} W/cm{sup 2} to 10{sup 16} W/cm{sup 2}. In addition, the effect of laser wavelength on energy absorption at certain ionization mechanism is discussed when the Keldysh parameter is fixed. Theoretical results show that: (1) at the fixed laser wavelength, the relationship between the energy absorption and laser intensity shows a good fit of E = c{sub M}I{sup N} (N is the number of photons absorbed to free from the valence band) when multiphoton ionization dominates; (2) while when tunnel ionization becomes significant, the relationship coincides with the expression of E = c{sub T}I{sup n} (n < N).

  13. Classical and quantum dynamics of a perfect fluid scalar-energy dependent metric cosmology

    NASA Astrophysics Data System (ADS)

    Khodadi, M.; Nozari, K.; Vakili, B.

    2016-05-01

    Inspired from the idea of minimally coupling of a real scalar field to geometry, we investigate the classical and quantum models of a flat energy-dependent FRW cosmology coupled to a perfect fluid in the framework of the scalar-rainbow metric gravity. We use the standard Schutz' representation for the perfect fluid and show that under a particular energy-dependent gauge fixing, it may lead to the identification of a time parameter for the corresponding dynamical system. It is shown that, under some circumstances on the minisuperspace prob energy, the classical evolution of the of the universe represents a late time expansion coming from a bounce instead of the big-bang singularity. Then we go forward by showing that this formalism gives rise to a Schrödinger-Wheeler-DeWitt equation for the quantum-mechanical description of the model under consideration, the eigenfunctions of which can be used to construct the wave function of the universe. We use the resulting wave function in order to investigate the possibility of the avoidance of classical singularities due to quantum effects by means of the many-worlds and Bohmian interpretation of quantum cosmology.

  14. On the origin of the temperature dependence of the supercoiling free energy.

    PubMed Central

    Delrow, J J; Heath, P J; Schurr, J M

    1997-01-01

    Monte Carlo simulations using temperature-invariant torsional and bending rigidities fail to predict the rather steep decline of the experimental supercoiling free energy with increasing temperature, and consequently fail to predict the correct sign and magnitude of the supercoiling entropy. To illustrate this problem, values of the twist energy parameter (E(T)), which governs the supercoiling free energy, were simulated using temperature-invariant torsion and bending potentials and compared to experimental data on pBR322 over a range of temperatures. The slope, -dE(T)/dT, of the simulated values is also compared to the slope derived from previous calorimetric data. The possibility that the discrepancies arise from some hitherto undetected temperature dependence of the torsional rigidity was investigated. The torsion elastic constant of an 1876-bp restriction fragment of pBR322 was measured by time-resolved fluorescence polarization anisotropy of intercalated ethidium over the range 278-323 K, and found to decline substantially over that interval. Simulations of a 4349-bp model DNA were performed using these measured temperature-dependent torsional rigidities. The slope, -dE(T)/dT, of the simulated data agrees satisfactorily with the slope derived from previous calorimetric measurements, but still lies substantially below that of Duguet's data. Models that involve an equilibrium between different secondary structure states with different intrinsic twists and torsion constants provide the most likely explanation for the variation of the torsion constant with T and other pertinent observations. PMID:9370462

  15. Dependence of hydropower energy generation on forests in the Amazon Basin at local and regional scales

    PubMed Central

    Stickler, Claudia M.; Coe, Michael T.; Costa, Marcos H.; Nepstad, Daniel C.; McGrath, David G.; Dias, Livia C. P.; Rodrigues, Hermann O.; Soares-Filho, Britaldo S.

    2013-01-01

    Tropical rainforest regions have large hydropower generation potential that figures prominently in many nations’ energy growth strategies. Feasibility studies of hydropower plants typically ignore the effect of future deforestation or assume that deforestation will have a positive effect on river discharge and energy generation resulting from declines in evapotranspiration (ET) associated with forest conversion. Forest loss can also reduce river discharge, however, by inhibiting rainfall. We used land use, hydrological, and climate models to examine the local “direct” effects (through changes in ET within the watershed) and the potential regional “indirect” effects (through changes in rainfall) of deforestation on river discharge and energy generation potential for the Belo Monte energy complex, one of the world’s largest hydropower plants that is currently under construction on the Xingu River in the eastern Amazon. In the absence of indirect effects of deforestation, simulated deforestation of 20% and 40% within the Xingu River basin increased discharge by 4–8% and 10–12%, with similar increases in energy generation. When indirect effects were considered, deforestation of the Amazon region inhibited rainfall within the Xingu Basin, counterbalancing declines in ET and decreasing discharge by 6–36%. Under business-as-usual projections of forest loss for 2050 (40%), simulated power generation declined to only 25% of maximum plant output and 60% of the industry’s own projections. Like other energy sources, hydropower plants present large social and environmental costs. Their reliability as energy sources, however, must take into account their dependence on forests. PMID:23671098

  16. The importance of temperature dependent energy gap in the understanding of high temperature thermoelectric properties

    NASA Astrophysics Data System (ADS)

    Singh, Saurabh; Pandey, Sudhir K.

    2016-10-01

    In this work, we show the importance of temperature dependent energy band gap, E g (T), in understanding the high temperature thermoelectric (TE) properties of material by considering LaCoO3 (LCO) and ZnV2O4 (ZVO) compounds as a case study. For the fix value of band gap, E g , deviation in the values of α has been observed above 360 K and 400 K for LCO and ZVO compounds, respectively. These deviation can be overcomed by consideration of temperature dependent band gap. The change in used value of E g with respect to temperature is ∼4 times larger than that of In As. This large temperature dependence variation in E g can be attributed to decrement in the effective on-site Coulomb interaction due to lattice expansion. At 600 K, the value of ZT for n and p-doped, LCO is ∼0.35 which suggest that it can be used as a potential material for TE device. This work clearly suggest that one should consider the temperature dependent band gap in predicting the high temperature TE properties of insulating materials.

  17. Low energy cosmic ray positron fraction explained by charge-sign dependent solar modulation.

    PubMed

    Maccione, Luca

    2013-02-22

    We compute cosmic ray (CR) nuclei, proton, antiproton, electron, and positron spectra below 1 TeV at Earth by means of a detailed transport description in the galaxy and in the solar system. CR spectra below 10 GeV are strongly modified by charge-sign dependent propagation effects. These depend on the polarity of the solar magnetic field and therefore vary with the solar cycle. The puzzling discrepancy between the low-energy positron fraction measured by PAMELA and AMS-01 is then easily explained by their different data-taking epochs. We reproduce the observed spectra of CR light nuclei within the same galactic and solar-system propagation model.

  18. Biophysical Insights from Temperature-Dependent Single-Molecule Förster Resonance Energy Transfer

    NASA Astrophysics Data System (ADS)

    Holmstrom, Erik D.; Nesbitt, David J.

    2016-05-01

    Single-molecule fluorescence microscopy techniques can be used in combination with micrometer length-scale temperature control and Förster resonance energy transfer (FRET) in order to gain detailed information about fundamental biophysical phenomena. In particular, this combination of techniques has helped foster the development of remarkable quantitative tools for studying both time- and temperature-dependent structural kinetics of biopolymers. Over the past decade, multiple research efforts have successfully incorporated precise spatial and temporal control of temperature into single-molecule FRET (smFRET)-based experiments, which have uncovered critical thermodynamic information on a wide range of biological systems such as conformational dynamics of nucleic acids. This review provides an overview of various temperature-dependent smFRET approaches from our laboratory and others, highlighting efforts in which such methods have been successfully applied to studies of single-molecule nucleic acid folding.

  19. Nuclear level density of even-even nuclei with temperature-dependent pairing energy

    NASA Astrophysics Data System (ADS)

    Dehghani, V.; Alavi, S. A.

    2016-10-01

    The influence of using a temperature-dependent pairing term on the back-shifted Fermi gas (BSFG) model of nuclear level density of some even-even nuclei has been investigated. We have chosen an approach to determine the adjustable parameters from theoretical calculations, directly. The exact Ginzburg-Landau (EGL) theory was used to determine the temperature-dependent pairing energy as back-shifted parameter of the BSFG model. The level density parameter of the BSFG model has been determined through the Thomas-Fermi approximation. The level densities of 96Mo, 106,112Cd, 106,108Pd, 164Dy, 232Th, 238U and heat capacities of 96Mo and 164Dy nuclei were calculated. Good agreement between theory and experiment was observed.

  20. Opera-Reassessing Data on the Energy Dependence of the Speed of Neutrinos

    NASA Astrophysics Data System (ADS)

    Amelino-Camelia, Giovanni; Gubitosi, Giulia; Loret, Niccoló; Mercati, Flavio; Rosati, Giacomo; Lipari, Paolo

    We offer a preliminary exploration of the two sides of the challenge provided by the recent OPERA data on superluminal neutrinos. On one side we stress that some aspects of this result are puzzling even from the perspective of the wild quantum-gravity literature, where arguments in favor of the possibility of superluminal propagation have been presented, but not considering the possibility of such a sizeable effect for neutrinos of such low energies. We feel this must encourage particularly severe scrutiny of the OPERA result. On the other side, we notice that the OPERA result is reasonably consistent with μ-neutrino-speed data previously obtained at FERMILAB, reported in papers of 2007 and 1979. And it is intriguing that these FERMILAB79 and FERMILAB07 results, when combined with the new OPERA result, in principle provide a window on μ-neutrino speeds at different energies broad enough to compare alternative phenomenological models. We test the discriminating power of such an approach by using as illustrative examples the case of special-relativistic tachyons, the case of momentum-independent violations of the special-relativistic speed law, and the cases of linear and quadratic energy dependence of the speed of ultrarelativistic muon neutrinos. Even just using μ-neutrino data in the range from ~3 GeVs to ~200 GeVs the special-relativistic tachyon and the quadratic-dependence case are clearly disfavoured. The linear-dependence case gives a marginally consistent picture and the momentum-independent scenario fits robustly the data. We also comment on Supernova 1987a and its relevance for consideration of other neutrino species, also in relation with some scenarios that appeared in the large-extra-dimension literature.

  1. Centrality-dependent forward J/ψ production in high energy proton-nucleus collisions

    NASA Astrophysics Data System (ADS)

    Ducloué, B.; Lappi, T.; Mäntysaari, H.

    2016-03-01

    Forward J/ψ production and suppression in high energy proton-nucleus collisions can be an important probe of gluon saturation. In an earlier work we studied this process in the Color Glass Condensate framework and showed that using the Glauber approach to extrapolate the dipole cross section of a proton to a nucleus leads to results closer to experimental data than previous calculations in this framework. Here we investigate the centrality dependence of the nuclear suppression in this model and show a comparison of our results with recent LHC data.

  2. The energy dependence and surface morphology of Kapton (trademark) degradation under atomic oxygen bombardment

    NASA Technical Reports Server (NTRS)

    Ferguson, D. C.

    1984-01-01

    Data from laboratory simulations and from samples returned from STS-8 are used to derive the energy dependence of the mass loss rate of Kapton under atomic oxygen bombardment and to discuss the development of surface structure and its effect on erosion rates. It is concluded that all the laboratory data from discharge and flow tubes and from accelerated beams, along with the orbital data from STS-3 through STS-8, can be accommodated by a rate of mass loss that varies with impact energy normal to the surface. It is hypothesized that increases of mass loss rate with exposure time may be due to trapping of the incoming atoms by the surface structure which develops.

  3. THE ENERGY DEPENDENCE OF 209Bi FRAGMENTATION IN RELATIVISTIC NUCLEAR COLLISIONS

    SciTech Connect

    Aleklett, K.; Morrissey, D.J.; Loveland, W.; McGaughey, P.L.; Seaborg, g.T.

    1980-07-01

    The results of cross-section measurements for the reactions {sup 209}Bi({sup 12}C,X)Au, E = 4.8 and 25.2 GeV and {sup 209}Bi({sup 20}Ne,X)Au, E = 8.0 GeV are reported. The observed yields of the gold isotopes show a similar dependence on mass number for each reaction, differing slightly in the position of the centroid of the distribution. As the projectile energy increases, the inferred excitation energy of the primary residues remains the same or decreases slightly. This observation is in agreement with the predictions of the intranuclear cascade model of relativistic heavy ion collisions.

  4. Density dependence of the nuclear symmetry energy from measurements of neutron radii in nuclei

    SciTech Connect

    Viñas, X.; Centelles, M.; Roca-Maza, X.; Warda, M.

    2014-07-23

    We study the density dependence of the nuclear symmetry energy, characterized by its slope parameter L, by means of the information provided by the neutron radius and the neutron skin thickness in finite nuclei. These quantities are extracted from the analysis of data obtained in antiprotonic atoms, from the parity-violating asymmetry at low-momentum transfer in polarized electron scattering in {sup 208}Pb, and from the electric dipole polarizability obtained via polarized proton inelastic scattering at forward angles in {sup 208}Pb. All these experiments provide different constraints on the slope L of the symmetry energy but the corresponding values have a considerable overlap in a range around 50 MeV ≤ L ≤ 70 MeV, in a reasonable agreement with other estimates that use different observables and methods to extract L.

  5. Density dependence of the nuclear symmetry energy from measurements of neutron radii in nuclei

    NASA Astrophysics Data System (ADS)

    Viñas, X.; Centelles, M.; Roca-Maza, X.; Warda, M.

    2014-07-01

    We study the density dependence of the nuclear symmetry energy, characterized by its slope parameter L, by means of the information provided by the neutron radius and the neutron skin thickness in finite nuclei. These quantities are extracted from the analysis of data obtained in antiprotonic atoms, from the parity-violating asymmetry at low-momentum transfer in polarized electron scattering in 208Pb, and from the electric dipole polarizability obtained via polarized proton inelastic scattering at forward angles in 208Pb. All these experiments provide different constraints on the slope L of the symmetry energy but the corresponding values have a considerable overlap in a range around 50 MeV ≤ L ≤ 70 MeV, in a reasonable agreement with other estimates that use different observables and methods to extract L.

  6. Effect of surface energy on size-dependent deformation twinning of defect-free Au nanowires.

    PubMed

    Hwang, Byungil; Kang, Mijeong; Lee, Subin; Weinberger, Christopher R; Loya, Phillip; Lou, Jun; Oh, Sang Ho; Kim, Bongsoo; Han, Seung Min

    2015-10-14

    In this study, we report the size-dependent transition of deformation twinning studied using in situ SEM/TEM tensile testing of defect-free [110] Au nanowires/ribbons with controlled geometry. The critical dimension below which the ordinary plasticity transits to deformation twinning is experimentally determined to be ∼170 nm for Au nanowires with equilateral cross-sections. Nanoribbons with a fixed thickness but increased width-to-thickness ratios (9 : 1) were also studied to show that an increase in the surface energy due to the crystal re-orientation suppresses the deformation twinning. Molecular dynamics simulations confirmed that the transition from partial dislocation mediated plasticity to perfect dislocation plasticity with increase in the width-to-thickness ratio is due to the effect of the surface energy. PMID:26350050

  7. Energy dependence of the band-limited noise in black hole X-ray binaries★

    NASA Astrophysics Data System (ADS)

    Stiele, H.; Yu, W.

    2015-10-01

    Black hole low-mass X-ray binaries show a variety of variability features, which manifest as narrow peak-like structures superposed on broad noise components in power density spectra in the hard X-ray emission. In this work, we study variability properties of the band-limited noise component during the low-hard state for a sample of black hole X-ray binaries. We investigate the characteristic frequency and amplitude of the band-limited noise component and study covariance spectra. For observations that show a noise component with a characteristic frequency above 1 Hz in the hard energy band (4-8 keV), we found this very same component at a lower frequency in the soft band (1-2 keV). This difference in characteristic frequency is an indication that while both the soft and the hard band photons contribute to the same band-limited noise component, which likely represents the modulation of the mass accretion rate, the origin of the soft photons is actually further away from the black hole than the hard photons. Thus, the soft photons are characterized by larger radii, lower frequencies and softer energies, and are probably associated with a smaller optical depth for Comptonization up-scattering from the outer layer of the corona, or suggest a temperature gradient of the corona. We interpret this energy dependence within the picture of energy-dependent power density states as a hint that the contribution of the up-scattered photons originating in the outskirts of the Comptonizing corona to the overall emission in the soft band is becoming significant.

  8. On the cross-helicity dependence of the energy spectrum in magnetohydrodynamic turbulence

    SciTech Connect

    Podesta, J. J.

    2011-01-15

    Phenomenological theories of strong incompressible magnetohydrodynamic (MHD) turbulence derived by Goldreich and Sridhar (GS) in 1995 and by Boldyrev in 2006 are only applicable to turbulence with vanishing cross-helicity. In this study, these two theories are generalized to treat turbulence with nonvanishing cross-helicity in such a way that the relation (w{sup +}/w{sup -}){sup 2}=({epsilon}{sup +}/{epsilon}{sup -}){sup 2} observed in numerical simulations is satisfied. The average energy (second order structure function) in the generalized GS theory is E(r{sub perpendicular})={phi}{sub 1}({sigma}{sub c})({epsilon}r{sub perpendicular}){sup 2/3} and that in the generalized Boldyrev theory is E(r{sub perpendicular})={phi}{sub 2}({sigma}{sub c})(v{sub A{epsilon}}r{sub perpendicular}){sup 1/2}, where the function {phi}({sigma}{sub c}) describes the dependence on the normalized cross-helicity {sigma}{sub c}. The form of the function {phi}({sigma}{sub c}) is derived through a renormalization of the variable {sigma}{sub c} that yields a one parameter family of solutions. The theory derived by Lithwick, Goldreich, and Sridhar (LGS) in 2007 is a special case of the generalized GS theory derived here; however, other generalizations of the GS theory are obtained that have a different cross-helicity dependence than the LGS theory. This new class of solutions and similar generalizations of Boldyrev's theory are investigated to see how the energy cascade rate {epsilon} changes as a function of {sigma}{sub c} when the energy at a given scale is held fixed. The generalization of Boldyrev's theory derived here is applicable to homogeneous MHD turbulence in the solar wind, for example, and can be used to obtain the turbulent dissipation rate {epsilon} from measurements of the energy spectrum and the normalized cross-helicity.

  9. Phase-dependent dynamic potential of magnetically coupled two-degree-of-freedom bistable energy harvester

    PubMed Central

    Kim, Pilkee; Nguyen, Minh Sang; Kwon, Ojin; Kim, Young-Jin; Yoon, Yong-Jin

    2016-01-01

    A system of magnetically coupled oscillators has been recently considered as a promising compact structure to integrate multiple bistable energy harvesters (BEHs), but its design is not straightforward owing to its varying potential energy pattern, which has not been understood completely yet. This study introduces the concept of phase-dependent dynamic potential in a magnetically coupled BEH system with two degrees of freedom (DOFs) to explain the underlying principle of the complicated dynamics of the system. Through theoretical simulations and analyses, two distinct dynamic regimes, called the out-of-phase and in-phase mode regimes in this report, are found to exist in the frequency regions of the 1st and 2nd primary intrawell resonances. For the out-of-phase mode regime, the frequency displacement (and output power) responses of the 2-DOF BEH system exhibit typical double-well dynamics, whereas for the in-phase mode regime, only single-well dynamics is observed though the system is statically bistable. These dynamic regimes are also revealed to be caused by the difference in the dynamic potential energy trajectories propagating on a high-dimensional potential energy surface. The present approach to the dynamics of the 2-DOF BEH system can be extended and applied to higher-DOF systems, which sheds light on compact and efficient designs of magnetically coupled BEH chain structures. PMID:27677356

  10. Novel pulsed particle accelerator for energy dependent positron re-emission experiments.

    PubMed

    Grill, Niklas; Piochacz, Christian; Zimnik, Samantha; Hugenschmidt, Christoph

    2016-05-01

    We report on a novel device for particle acceleration based on elevation of the potential energy of beam pulses. This so-called energy elevator is particularly beneficial if both the particle source and the sample have to be near ground potential due to experimental constraints. We applied this new technique to enable depth dependent measurements of re-emitted positrons using the surface spectrometer at the NEPOMUC positron beam facility. First, a two-stage bunching system is used to generate positron pulses with a repetition rate of 5 MHz and a duration of 1.663(5) ns before their energy is raised to several keV. The whole system was shown to work with an exceptional efficiency of 88%. We demonstrated the usability of our setup by investigating the positron re-emission spectra of Ni and Pd as function of positron implantation energy. For Ni the positron work function could be determined to be ΦNi (+)=-1.4(2)eV. In addition, as predicted by theory, our experimental findings imply a positive positron work function for Pd.

  11. Structure of Exotic Mg Isotopes and Temperature Dependence of the Symmetry Energy of Finite Nuclei

    NASA Astrophysics Data System (ADS)

    Gaidarov, M. K.; Sarriguren, P.; Antonov, A. N.; Kadrev, D. N.; Moya de Guerra, E.

    2016-06-01

    We study various ground-state properties of neutron-rich and neutron-deficient Mg isotopes with A=20-36 in the framework of the self-consistent deformed Skyrme-Hartree- Fock plus BCS method. The nuclear symmetry energy is investigated for the same isotopic chain following the theoretical approach based on the coherent density fluctuation model. The results of the calculations show that the behavior of the nuclear charge radii and the nuclear matter properties in the Mg isotopic chain is closely related to the nuclear deformation. The temperature dependence of the symmetry energy for isotopic chains of even-even Ni (A=58- 82), Sn (A=124-152), and Pb (A=202-214) nuclei is investigated in the framework of the local density approximation. The results for the thermal evolution of the symmetry energy coefficient show that for all isotopic chains considered and for both Skyrme forces used in the calculations the symmetry energy coefficient decreases with the increase of the mass number in the temperature interval T = 0-5 MeV.

  12. Phase-dependent dynamic potential of magnetically coupled two-degree-of-freedom bistable energy harvester

    NASA Astrophysics Data System (ADS)

    Kim, Pilkee; Nguyen, Minh Sang; Kwon, Ojin; Kim, Young-Jin; Yoon, Yong-Jin

    2016-09-01

    A system of magnetically coupled oscillators has been recently considered as a promising compact structure to integrate multiple bistable energy harvesters (BEHs), but its design is not straightforward owing to its varying potential energy pattern, which has not been understood completely yet. This study introduces the concept of phase-dependent dynamic potential in a magnetically coupled BEH system with two degrees of freedom (DOFs) to explain the underlying principle of the complicated dynamics of the system. Through theoretical simulations and analyses, two distinct dynamic regimes, called the out-of-phase and in-phase mode regimes in this report, are found to exist in the frequency regions of the 1st and 2nd primary intrawell resonances. For the out-of-phase mode regime, the frequency displacement (and output power) responses of the 2-DOF BEH system exhibit typical double-well dynamics, whereas for the in-phase mode regime, only single-well dynamics is observed though the system is statically bistable. These dynamic regimes are also revealed to be caused by the difference in the dynamic potential energy trajectories propagating on a high-dimensional potential energy surface. The present approach to the dynamics of the 2-DOF BEH system can be extended and applied to higher-DOF systems, which sheds light on compact and efficient designs of magnetically coupled BEH chain structures.

  13. Investigation of the energy dependence of the orbital light curve in LS 5039

    NASA Astrophysics Data System (ADS)

    Chang, Z.; Zhang, S.; Ji, L.; Chen, Y. P.; Kretschmar, P.; Kuulkers, E.; Collmar, W.; Liu, C. Z.

    2016-08-01

    LS 5039 is so far the best studied γ-ray binary system at multi-wavelength energies. A time resolved study of its spectral energy distribution (SED) shows that above 1 keV its power output is changing along its binary orbit as well as being a function of energy. To disentangle the energy dependence of the power output as a function of orbital phase, we investigated in detail the orbital light curves as derived with different telescopes at different energy bands. We analysed the data from all existing INTEGRAL/IBIS/ISGRI observations of the source and generated the most up-to-date orbital light curves at hard X-ray energies. In the γ-ray band, we carried out orbital phase-resolved analysis of Fermi-LAT data between 30 MeV and 10 GeV in 5 different energy bands. We found that, at ≲100 MeV and ≳1 TeV the peak of the γ-ray emission is near orbital phase 0.7, while between ˜100 MeV and ˜1 GeV it moves close to orbital phase 1.0 in an orbital anti-clockwise manner. This result suggests that the transition region in the SED at soft γ-rays (below a hundred MeV) is related to the orbital phase interval of 0.5-1.0 but not to the one of 0.0-0.5, when the compact object is "behind" its companion. Another interesting result is that between 3 and 20 GeV no orbital modulation is found, although Fermi-LAT significantly (˜18σ) detects LS 5039. This is consistent with the fact that at these energies, the contributions to the overall emission from the inferior conjunction phase region (INFC, orbital phase 0.45 to 0.9) and from the superior conjunction phase region (SUPC, orbital phase 0.9 to 0.45) are equal in strength. At TeV energies the power output is again dominant in the INFC region and the flux peak occurs at phase ˜0.7.

  14. Investigation of the energy dependence of the orbital light curve in LS 5039

    NASA Astrophysics Data System (ADS)

    Chang, Z.; Zhang, S.; Ji, L.; Chen, Y. P.; Kretschmar, P.; Kuulkers, E.; Collmar, W.; Liu, C. Z.

    2016-11-01

    LS 5039 is so far the best-studied γ-ray binary system at multiwavelength energies. A time-resolved study of its spectral energy distribution (SED) shows that above 1 keV its power output is changing along its binary orbit as well as being a function of energy. To disentangle the energy dependence of the power output as a function of orbital phase, we investigated in detail the orbital light curves as derived with different telescopes at different energy bands. We analysed the data from all existing International Gamma-Ray Astrophysics Laboratory (INTEGRAL)/INTEGRAL on-board Imager/INTEGRAL Soft Gamma-Ray Imager observations of the source and generated the most up-to-date orbital light curves at hard X-ray energies. In the γ-ray band, we carried out orbital phase-resolved analysis of Fermi-Large Area Telescope (LAT) data between 30 MeV and 10 GeV in five different energy bands. We found that, at ≲100 MeV and ≳1 TeV the peak of the γ-ray emission is near orbital phase 0.7, while between ˜100 MeV and ˜1 GeV it moves close to orbital phase 1.0 in an orbital anticlockwise manner. This result suggests that the transition region in the SED at soft γ-rays (below a hundred MeV) is related to the orbital phase interval of 0.5-1.0 but not to the one of 0.0-0.5, when the compact object is `behind' its companion. Another interesting result is that between 3 and 20 GeV no orbital modulation is found, although Fermi-LAT significantly (˜18σ) detects LS 5039. This is consistent with the fact that at these energies, the contributions to the overall emission from the inferior conjunction phase region (INFC, orbital phase 0.45-0.9) and from the superior conjunction phase region (orbital phase 0.9-0.45) are equal in strength. At TeV energies the power output is again dominant in the INFC region and the flux peak occurs at phase ˜0.7.

  15. Scale dependency of fracture energy and estimates thereof via dynamic rupture solutions with strong thermal weakening

    NASA Astrophysics Data System (ADS)

    Viesca, R. C.; Garagash, D.

    2013-12-01

    Seismological estimates of fracture energy show a scaling with the total slip of an earthquake [e.g., Abercrombie and Rice, GJI 2005]. Potential sources for this scale dependency are coseismic fault strength reductions that continue with increasing slip or an increasing amount of off-fault inelastic deformation with dynamic rupture propagation [e.g., Andrews, JGR 2005; Rice, JGR 2006]. Here, we investigate the former mechanism by solving for the slip dependence of fracture energy at the crack tip of a dynamically propagating rupture in which weakening takes place by strong reductions of friction via flash heating of asperity contacts and thermal pressurization of pore fluid leading to reductions in effective normal stress. Laboratory measurements of small characteristic slip evolution distances for friction (~10 μm at low slip rates of μm-mm/s, possibly up to 1 mm for slip rates near 0.1 m/s) [e.g., Marone and Kilgore, Nature 1993; Kohli et al., JGR 2011] imply that flash weakening of friction occurs at small slips before any significant thermal pressurization and may thus have a negligible contribution to the total fracture energy [Brantut and Rice, GRL 2011; Garagash, AGU 2011]. The subsequent manner of weakening under thermal pressurization (the dominant contributor to fracture energy) spans a range of behavior from the deformation of a finite-thickness shear zone in which diffusion is negligible (i.e., undrained-adiabatic) to that in which large-scale diffusion obscures the existence of a thin shear zone and thermal pressurization effectively occurs by the heating of slip on a plane. Separating the contribution of flash heating, the dynamic rupture solutions reduce to a problem with a single parameter, which is the ratio of the undrained-adiabatic slip-weakening distance (δc) to the characteristic slip-on-a-plane slip-weakening distance (L*). However, for any value of the parameter, there are two end-member scalings of the fracture energy: for small slip

  16. Continuous energy, multi-dimensional discrete ordinates transport calculations for problem dependent resonance treatment

    NASA Astrophysics Data System (ADS)

    Zhong, Zhaopeng

    In the past twenty 20 years considerable progress has been made in developing new methods for solving the multi-dimensional transport problem. However the effort devoted to the resonance self-shielding calculation has lagged, and much less progress has been made in enhancing resonance-shielding techniques for generating problem-dependent multi-group cross sections (XS) for the multi-dimensional transport calculations. In several applications, the error introduced by self-shielding methods exceeds that due to uncertainties in the basic nuclear data, and often they can be the limiting factor on the accuracy of the final results. This work is to improve the accuracy of the resonance self-shielding calculation by developing continuous energy multi-dimensional transport calculations for problem dependent self-shielding calculations. A new method has been developed, it can calculate the continuous-energy neutron fluxes for the whole two-dimensional domain, which can be utilized as weighting function to process the self-shielded multi-group cross sections for reactor analysis and criticality calculations, and during this process, the two-dimensional heterogeneous effect in the resonance self-shielding calculation can be fully included. A new code, GEMINEWTRN (Group and Energy-Pointwise Methodology Implemented in NEWT for Resonance Neutronics) has been developed in the developing version of SCALE [1], it combines the energy pointwise (PW) capability of the CENTRM [2] with the two-dimensional discrete ordinates transport capability of lattice physics code NEWT [14]. Considering the large number of energy points in the resonance region (typically more than 30,000), the computational burden and memory requirement for GEMINEWTRN is tremendously large, some efforts have been performed to improve the computational efficiency, parallel computation has been implemented into GEMINEWTRN, which can save the computation and memory requirement a lot; some energy points reducing

  17. Energy-dependent motion of TonB in the Gram-negative bacterial inner membrane.

    PubMed

    Jordan, Lorne D; Zhou, Yongyao; Smallwood, Chuck R; Lill, Yoriko; Ritchie, Ken; Yip, Wai Tak; Newton, Salete M; Klebba, Phillip E

    2013-07-01

    Gram-negative bacteria acquire iron with TonB-dependent uptake systems. The TonB-ExbBD inner membrane complex is hypothesized to transfer energy to outer membrane (OM) iron transporters. Fluorescence microscopic characterization of green fluorescent protein (GFP)-TonB hybrid proteins revealed an unexpected, restricted localization of TonB in the cell envelope. Fluorescence polarization measurements demonstrated motion of TonB in living cells, which likely was rotation. By determining the anisotropy of GFP-TonB in the absence and presence of inhibitors, we saw the dependence of its motion on electrochemical force and on the actions of ExbBD. We observed higher anisotropy for GFP-TonB in energy-depleted cells and lower values in bacteria lacking ExbBD. However, the metabolic inhibitors did not change the anisotropy of GFP-TonB in ΔexbBD cells. These findings demonstrate that TonB undergoes energized motion in the bacterial cell envelope and that ExbBD couples this activity to the electrochemical gradient. The results portray TonB as an energized entity in a regular array underlying the OM bilayer, which promotes metal uptake through OM transporters by a rotational mechanism.

  18. Observation of Energy and Baseline Dependent Reactor Antineutrino Disappearance in the RENO Experiment.

    PubMed

    Choi, J H; Choi, W Q; Choi, Y; Jang, H I; Jang, J S; Jeon, E J; Joo, K K; Kim, B R; Kim, H S; Kim, J Y; Kim, S B; Kim, S Y; Kim, W; Kim, Y D; Ko, Y; Lee, D H; Lim, I T; Pac, M Y; Park, I G; Park, J S; Park, R G; Seo, H; Seo, S H; Seon, Y G; Shin, C D; Siyeon, K; Yang, J H; Yeo, I S; Yu, I

    2016-05-27

    The RENO experiment has analyzed about 500 live days of data to observe an energy dependent disappearance of reactor ν[over ¯]_{e} by comparing their prompt signal spectra measured in two identical near and far detectors. In the period between August of 2011 and January of 2013, the far (near) detector observed 31 541 (290 775) electron antineutrino candidate events with a background fraction of 4.9% (2.8%). The measured prompt spectra show an excess of reactor ν[over ¯]_{e} around 5 MeV relative to the prediction from a most commonly used model. A clear energy and baseline dependent disappearance of reactor ν[over ¯]_{e} is observed in the deficit of the observed number of ν[over ¯]_{e}. Based on the measured far-to-near ratio of prompt spectra, we obtain sin^{2}2θ_{13}=0.082±0.009(stat)±0.006(syst) and |Δm_{ee}^{2}|=[2.62_{-0.23}^{+0.21}(stat)_{-0.13}^{+0.12}(syst)]×10^{-3}  eV^{2}. PMID:27284648

  19. Incident energy and charge deposition dependences of electron transmission through a microsized tapered glass capillary

    NASA Astrophysics Data System (ADS)

    Wickramarachchi, S. J.; Ikeda, T.; Dassanayake, B. S.; Keerthisinghe, D.; Tanis, J. A.

    2016-09-01

    An experimental study of electron transmission and guiding through a tapered glass capillary has been performed. Electrons were transmitted for tilt angles up to ∼6.5° and ∼9.5° (laboratory angles) for incident energies of 500 and 1000 eV, respectively. It is found that elastic and inelastic contributions give rise to distinguishable peaks in the transmitted profile. For 500 eV elastic transmission dominates the profile, while for 1000 eV both elastic and inelastic contributions are present. The transmission for both energies was studied as a function of the charge (time) deposition and found to be strongly dependent. Results suggest fundamental differences between 500 and 1000 eV incident electrons. For 500 eV the transmission slowly increases suggesting charge up of the capillary wall, reaching relative stability with infrequent breakdowns for all angles investigated. For 1000 eV for tilt angles near zero degrees the time dependent profile shows oscillations in the transmission, which never reached a stable condition, while for the larger angle investigated the transmission reached near equilibrium. Inelastic processes dominated the transmission for 1000 eV even at very small tilt angles, but was generally elastic (due to Coulomb deflection) for 500 eV even for the largest tilt angle measured.

  20. Amino-acid-dependent main-chain torsion-energy terms for protein systems.

    PubMed

    Sakae, Yoshitake; Okamoto, Yuko

    2013-02-14

    Many commonly used force fields for protein systems such as AMBER, CHARMM, GROMACS, OPLS, and ECEPP have amino-acid-independent force-field parameters for main-chain torsion-energy terms. Here, we propose a new type of amino-acid-dependent torsion-energy terms in the force fields. As an example, we applied this approach to AMBER ff03 force field and determined new amino-acid-dependent parameters for ψ (N-C(α)-C-N) and ζ (C(β)-C(α)-C-N) angles for each amino acid by using our optimization method, which is one of the knowledge-based approach. In order to test the validity of the new force-field parameters, we then performed folding simulations of α-helical and β-hairpin peptides, using the optimized force field. The results showed that the new force-field parameters gave structures more consistent with the experimental implications than the original AMBER ff03 force field.

  1. Review of relative biological effectiveness dependence on linear energy transfer for low-LET radiations.

    PubMed

    Hunter, Nezahat; Muirhead, Colin R

    2009-03-01

    Information on Japanese A-bomb survivors exposed to gamma radiation has been used to estimate cancer risks for the whole range of photon (x-rays) and electron energies which are commonly encountered by radiation workers in the work place or by patients and workers in diagnostic radiology. However, there is some uncertainty regarding the radiation effectiveness of various low-linear energy transfer (low-LET) radiations (x-rays, gamma radiation and electrons). In this paper we review information on the effectiveness of low-LET radiations on the basis of epidemiological and in vitro radiobiological studies. Data from various experimental studies for chromosome aberrations and cell transformation in human lymphocytes and from epidemiological studies of the Japanese A-bomb survivors, patients medically exposed to radiation for diagnostic and therapeutic procedures, and occupational exposures of nuclear workers are considered. On the basis of in vitro cellular radiobiology, there is considerable evidence that the relative biological effectiveness (RBE) of high-energy low-LET radiation (gamma radiation, electrons) is less than that of low-energy low-LET radiation (x-rays, betas). This is a factor of about 3 to 4 for 29 kVp x-rays (e.g. as in diagnostic radiation exposures of the female breast) and for tritium beta-rays (encountered in parts of the nuclear industry) relative to Co-60 gamma radiation and 2-5 MeV gamma-rays (as received by the Japanese A-bomb survivors). In epidemiological studies, although for thyroid and breast cancer there appears to be a small tendency for the excess relative risks to decrease as the radiation energy increases for low-LET radiations, it is not statistically feasible to draw any conclusion regarding an underlying dependence of cancer risk on LET for the nominally low-LET radiations. PMID:19225189

  2. Effect of coupled channels on the energy dependence of phenomenological optical potential parameters

    NASA Astrophysics Data System (ADS)

    Al-Rayashi, W. S.; Jaghoub, M. I.

    2016-06-01

    The phenomenological optical potential parameters are known to vary with incident energy due to sources of nonlocalities in the nucleon-nucleus elastic scattering process. Here we investigate the effect of one source, which is coupling the ground-state elastic channel to collective inelastic excitations on the energy dependence of the optical potential parameters. For incident energies in the range 10-70 MeV, we considered elastic and inelastic nucleon scattering from light, medium, and heavy nuclei ranging from 6Li to 208Pb. The potential parameters were first determined by fitting the elastic angular distributions only. Then we included coupling to collective excitation channels and determined the potential parameters that reproduced the elastic and inelastic angular distribution data simultaneously. Our results show that coupling to inelastic excitations reduces the energy variations of the potential parameters compared to that of the elastic scattering case. In particular, the our best fit values for the real part of the spin-orbit term are highly stable as a function of energy. The values of the surface imaginary term are not only more stable but are also reduced compared to the elastic case. The reduction is a direct consequence of the channel coupling accounting explicitly for part of the flux removed from the elastic channel. In the fitting process we also searched for the best fit values of the deformation parameters. Our values compare well with the corresponding ones obtained in previous works. Finally, we used our best fit values for the potential and deformation parameters to theoretically predict the total elastic, total cross section, and polarization data. The predicted values are in very good agreement with the experimental data.

  3. Review of relative biological effectiveness dependence on linear energy transfer for low-LET radiations.

    PubMed

    Hunter, Nezahat; Muirhead, Colin R

    2009-03-01

    Information on Japanese A-bomb survivors exposed to gamma radiation has been used to estimate cancer risks for the whole range of photon (x-rays) and electron energies which are commonly encountered by radiation workers in the work place or by patients and workers in diagnostic radiology. However, there is some uncertainty regarding the radiation effectiveness of various low-linear energy transfer (low-LET) radiations (x-rays, gamma radiation and electrons). In this paper we review information on the effectiveness of low-LET radiations on the basis of epidemiological and in vitro radiobiological studies. Data from various experimental studies for chromosome aberrations and cell transformation in human lymphocytes and from epidemiological studies of the Japanese A-bomb survivors, patients medically exposed to radiation for diagnostic and therapeutic procedures, and occupational exposures of nuclear workers are considered. On the basis of in vitro cellular radiobiology, there is considerable evidence that the relative biological effectiveness (RBE) of high-energy low-LET radiation (gamma radiation, electrons) is less than that of low-energy low-LET radiation (x-rays, betas). This is a factor of about 3 to 4 for 29 kVp x-rays (e.g. as in diagnostic radiation exposures of the female breast) and for tritium beta-rays (encountered in parts of the nuclear industry) relative to Co-60 gamma radiation and 2-5 MeV gamma-rays (as received by the Japanese A-bomb survivors). In epidemiological studies, although for thyroid and breast cancer there appears to be a small tendency for the excess relative risks to decrease as the radiation energy increases for low-LET radiations, it is not statistically feasible to draw any conclusion regarding an underlying dependence of cancer risk on LET for the nominally low-LET radiations.

  4. Pencil beam approach for correcting the energy dependence artifact in film dosimetry for IMRT verification.

    PubMed

    Kirov, Assen S; Caravelli, Gregory; Palm, Asa; Chui, Chen; LoSasso, Thomas

    2006-10-01

    The higher sensitivity to low-energy scattered photons of radiographic film compared to water can lead to significant dosimetric error when the beam quality varies significantly within a field. Correcting for this artifact will provide greater accuracy for intensity modulated radiation therapy (IMRT) verification dosimetry. A procedure is developed for correction of the film energy-dependent response by creating a pencil beam kernel within our treatment planning system to model the film response specifically. Film kernels are obtained from EGSnrc Monte Carlo simulations of the dose distribution from a 1 mm diameter narrow beam in a model of the film placed at six depths from 1.5 to 40 cm in polystyrene and solid water phantoms. Kernels for different area phantoms (50 x 50 cm2 and 25 x 25 cm2 polystyrene and 30 x 30 cm2 solid water) are produced. The Monte Carlo calculated kernel is experimentally verified with film, ion chamber and thermoluminescent dosimetry (TLD) measurements in polystyrene irradiated by a narrow beam. The kernel is then used in convolution calculations to, predict the film response in open and IMRT fields. A 6 MV photon beam and Kodak XV2 film in a polystyrene phantom are selected to test the method as they are often used in practice and can result in large energy-dependent artifacts. The difference in dose distributions calculated with the film kernel and the water kernel is subtracted from film measurements to obtain a practically film artifact free IMRT dose distribution for the Kodak XV2 film. For the points with dose exceeding 5 cGy (11% of the peak dose) in a large modulated field and a film measurement inside a large polystyrene phantom at depth of 10 cm, the correction reduces the fraction of pixels for which the film dose deviates from dose to water by more than 5% of the mean film dose from 44% to 6%.

  5. Quasiperiodic energy dependence of exciton relaxation kinetics in the sexithiophene crystal.

    PubMed

    Petelenz, Piotr; Zak, Emil

    2014-10-16

    Femtosecond kinetics of fluorescence rise in the sexithiophene crystal is studied on a microscopic model of intraband relaxation, where exciton energy is assumed to be dissipated by phonon-accompanied scattering, with the rates calculated earlier. The temporal evolution of the exciton population is described by a set of kinetic equations, solved numerically to yield the population buildup at the band bottom. Not only the time scale but also the shape of the rise curves is found to be unusually sensitive to excitation energy, exhibiting unique quasiperiodic dependence thereon, which is rationalized in terms of the underlying model. Further simulations demonstrate that the main conclusions are robust with respect to experimental factors such as finite temperature and inherent spectral broadening of the exciting pulse, while the calculated fluorescence rise times are found to be in excellent agreement with experimental data available to date. As the rise profiles are composed of a number of exponential contributions, which varies with excitation energy, the common practice of characterizing the population buildup in the emitting state by a single value of relaxation time turns out to be an oversimplification. New experiments giving further insight into the kinetics and mechanism of intraband exciton relaxation are suggested.

  6. Kinetic Energy Release dependence in the Photo Double Ionization of H2

    NASA Astrophysics Data System (ADS)

    Weber, Th.; Miyabe, S.; Belkacem, A.; McCurdy, C. W.; Lenz, U.; Jahnke, T.; Doerner, R.; Williams, J.; Landers, A.

    2012-06-01

    In the Photo Double Ionization (PDI) of hydrogen molecules with photon energies of 150eV we were able to probe the electronic two particle density as a function of the bond length, i.e. the Kinetic Energy Release (KER) of the ions, and the orientation of the molecular axis with respect to the polarization vector of the incoming ligh. We applied the COLTRIMS technique and measured two electrons and two protons in coincidence. We found a shift in the KER for σ and π transitions. While the KER is lower when the molecular axis is aligned parallel to the linear polarization vector (σ-σ), the KER for a perpendicular orientation (σ-π) is clearly higher by a little more than 1eV. Quantum mechanical ab initio calculations are able to quantify the shift in KER and the ratio for the two different transitions (β-parameter) for a broad range of photon energies (75 to 240eV). These results reflect the dependence of the σ and π amplitudes to the bond length. This shows that a simple KER measurement for horizontal and vertical polarization can be used to extract this information; it makes measuring the β-parameter as a function of KER obsolete.

  7. Exploring three-dimensional orbital imaging with energy-dependent photoemission tomography

    PubMed Central

    Weiß, S.; Lüftner, D.; Ules, T.; Reinisch, E. M.; Kaser, H.; Gottwald, A.; Richter, M.; Soubatch, S.; Koller, G.; Ramsey, M. G.; Tautz, F. S.; Puschnig, P.

    2015-01-01

    Recently, it has been shown that experimental data from angle-resolved photoemission spectroscopy on oriented molecular films can be utilized to retrieve real-space images of molecular orbitals in two dimensions. Here, we extend this orbital tomography technique by performing photoemission initial state scans as a function of photon energy on the example of the brickwall monolayer of 3,4,9,10-perylene tetracarboxylic dianhydride (PTCDA) on Ag(110). The overall dependence of the photocurrent on the photon energy can be well accounted for by assuming a plane wave for the final state. However, the experimental data, both for the highest occupied and the lowest unoccupied molecular orbital of PTCDA, exhibits an additional modulation attributed to final state scattering effects. Nevertheless, as these effects beyond a plane wave final state are comparably small, we are able, with extrapolations beyond the attainable photon energy range, to reconstruct three-dimensional images for both orbitals in agreement with calculations for the adsorbed molecule. PMID:26437297

  8. The Energy-Dependent Position of the IBEX Ribbon Due to the Solar Wind Structure

    NASA Astrophysics Data System (ADS)

    Swaczyna, Paweł; Bzowski, Maciej; Sokół, Justyna M.

    2016-08-01

    Observations of energetic neutral atoms (ENAs) allow for remote studies of the condition of plasma in the heliosphere and the neighboring local interstellar medium. The first results from the Interstellar Boundary Explorer (IBEX) revealed an arc-like enhancement of the ENA intensity in the sky, known as the ribbon. The ribbon was not expected from the heliospheric models prior to the launch of IBEX. One proposed explanation for the ribbon is the mechanism of secondary ENA emission. The ribbon reveals energy-dependent structure in the relative intensity along its circumference and in its position. That is, the geometric center of the ribbon varies systematically by about 10° in the energy range 0.7-4.3 keV. Here, we show by analytical modeling that this effect is a consequence of the helio-latitudinal structure of the solar wind reflected in the secondary ENAs. Along with a recently measured distance to the ribbon’s source just beyond the heliopause, our findings support the connection of the ribbon with the local interstellar magnetic field by the mechanism of secondary ENA emission. However, the magnitude of the center shift in the highest IBEX energy channel is much larger in the observations than expected from the modeling. This may be due to another, not currently recognized, process of ENA generation.

  9. Dependence of Structural and Electronic Properties of Uranium Monochalcogenides on Exchange--Correlation Energy Functionals

    NASA Astrophysics Data System (ADS)

    Suzuki, Shugo; Ohta, Hidehisa; Komatsu, Takumi; Yasuda, Sho

    2011-08-01

    We study the dependence of the structural properties of uranium monochalcogenides, UX where X = S, Se, and Te, as well as their electronic ones on the exchange--correlation energy functionals within the spin density functional theory, carrying out all electron calculations by the fully relativistic full-potential linear-combination-of-atomic-orbitals method. We employ two functionals of the local spin density approximation (LSDA) and two functionals of the generalized gradient approximations (GGA); the former two are the Perdew--Zunger and Perdew--Wang functionals and the latter two are the Perdew--Burke--Ernzerhof (PBE) and PBEsol functionals. We also examine the effects of the relativistic correction to the LSDA exchange part of each functional. We find that, for lattice constants, bulk moduli, and cohesive energies, the results of the calculations using the PBE functional are in the best agreement with the experimental results. On the contrary, we find that calculated total magnetic moments and one-electron energies are almost the same for all the LSDA and GGA functionals employed in this work, failing to improve the agreement between the calculated and experimental results even if the gradient and relativistic corrections are included. We also find that the relativistic correction plays minor roles in both the structural and electronic properties.

  10. Study of the energy dependence of the underlying event in proton-antiproton collisions

    SciTech Connect

    Nodulman, L.; Aaltonen, T; Albrow, M; Amerio, S.; Amidei, D; Anastassov, A.; Annovi, A; Antos, J; Apollinari, G.; Appel, J A; Arisawa, T

    2015-11-23

    We study charged particle production (p(T) > 0.5 GeV/c, vertical bar eta vertical bar < 0.8) in proton-antiproton collisions at total center-of-mass energies root s = 300 GeV, 900 GeV, and 1.96 TeV. We use the direction of the charged particle with the largest transverse momentum in each event to define three regions of eta - phi space: "toward", "away", and "transverse." The average number and the average scalar pT sum of charged particles in the transverse region are sensitive to the modeling of the "underlying event." The transverse region is divided into a MAX and MIN transverse region, which helps separate the "hard component" (initial and final-state radiation) from the "beam-beam remnant" and multiple parton interaction components of the scattering. The center-of-mass energy dependence of the various components of the event is studied in detail. The data presented here can be used to constrain and improve QCD Monte Carlo models, resulting in more precise predictions at the LHC energies of 13 and 14 TeV.

  11. The Energy-Dependent Position of the IBEX Ribbon Due to the Solar Wind Structure

    NASA Astrophysics Data System (ADS)

    Swaczyna, Paweł; Bzowski, Maciej; Sokół, Justyna M.

    2016-08-01

    Observations of energetic neutral atoms (ENAs) allow for remote studies of the condition of plasma in the heliosphere and the neighboring local interstellar medium. The first results from the Interstellar Boundary Explorer (IBEX) revealed an arc-like enhancement of the ENA intensity in the sky, known as the ribbon. The ribbon was not expected from the heliospheric models prior to the launch of IBEX. One proposed explanation for the ribbon is the mechanism of secondary ENA emission. The ribbon reveals energy-dependent structure in the relative intensity along its circumference and in its position. That is, the geometric center of the ribbon varies systematically by about 10° in the energy range 0.7–4.3 keV. Here, we show by analytical modeling that this effect is a consequence of the helio-latitudinal structure of the solar wind reflected in the secondary ENAs. Along with a recently measured distance to the ribbon’s source just beyond the heliopause, our findings support the connection of the ribbon with the local interstellar magnetic field by the mechanism of secondary ENA emission. However, the magnitude of the center shift in the highest IBEX energy channel is much larger in the observations than expected from the modeling. This may be due to another, not currently recognized, process of ENA generation.

  12. Study of the energy dependence of the underlying event in proton-antiproton collisions

    NASA Astrophysics Data System (ADS)

    Aaltonen, T.; Albrow, M.; Amerio, S.; Amidei, D.; Anastassov, A.; Annovi, A.; Antos, J.; Apollinari, G.; Appel, J. A.; Arisawa, T.; Artikov, A.; Asaadi, J.; Ashmanskas, W.; Auerbach, B.; Aurisano, A.; Azfar, F.; Badgett, W.; Bae, T.; Barbaro-Galtieri, A.; Barnes, V. E.; Barnett, B. A.; Barria, P.; Bartos, P.; Bauce, M.; Bedeschi, F.; Behari, S.; Bellettini, G.; Bellinger, J.; Benjamin, D.; Beretvas, A.; Bhatti, A.; Bland, K. R.; Blumenfeld, B.; Bocci, A.; Bodek, A.; Bortoletto, D.; Boudreau, J.; Boveia, A.; Brigliadori, L.; Bromberg, C.; Brucken, E.; Budagov, J.; Budd, H. S.; Burkett, K.; Busetto, G.; Bussey, P.; Butti, P.; Buzatu, A.; Calamba, A.; Camarda, S.; Campanelli, M.; Canelli, F.; Carls, B.; Carlsmith, D.; Carosi, R.; Carrillo, S.; Casal, B.; Casarsa, M.; Castro, A.; Catastini, P.; Cauz, D.; Cavaliere, V.; Cerri, A.; Cerrito, L.; Chen, Y. C.; Chertok, M.; Chiarelli, G.; Chlachidze, G.; Cho, K.; Chokheli, D.; Clark, A.; Clarke, C.; Convery, M. E.; Conway, J.; Corbo, M.; Cordelli, M.; Cox, C. A.; Cox, D. J.; Cremonesi, M.; Cruz, D.; Cuevas, J.; Culbertson, R.; d'Ascenzo, N.; Datta, M.; de Barbaro, P.; Demortier, L.; Deninno, M.; D'Errico, M.; Devoto, F.; Di Canto, A.; Di Ruzza, B.; Dittmann, J. R.; Donati, S.; D'Onofrio, M.; Dorigo, M.; Driutti, A.; Ebina, K.; Edgar, R.; Elagin, A.; Erbacher, R.; Errede, S.; Esham, B.; Farrington, S.; Fernández Ramos, J. P.; Field, R.; Flanagan, G.; Forrest, R.; Franklin, M.; Freeman, J. C.; Frisch, H.; Funakoshi, Y.; Galloni, C.; Garfinkel, A. F.; Garosi, P.; Gerberich, H.; Gerchtein, E.; Giagu, S.; Giakoumopoulou, V.; Gibson, K.; Ginsburg, C. M.; Giokaris, N.; Giromini, P.; Glagolev, V.; Glenzinski, D.; Gold, M.; Goldin, D.; Golossanov, A.; Gomez, G.; Gomez-Ceballos, G.; Goncharov, M.; González López, O.; Gorelov, I.; Goshaw, A. T.; Goulianos, K.; Gramellini, E.; Grosso-Pilcher, C.; Group, R. C.; Guimaraes da Costa, J.; Hahn, S. R.; Han, J. Y.; Happacher, F.; Hara, K.; Hare, M.; Harr, R. F.; Harrington-Taber, T.; Hatakeyama, K.; Hays, C.; Heinrich, J.; Herndon, M.; Hocker, A.; Hong, Z.; Hopkins, W.; Hou, S.; Hughes, R. E.; Husemann, U.; Hussein, M.; Huston, J.; Introzzi, G.; Iori, M.; Ivanov, A.; James, E.; Jang, D.; Jayatilaka, B.; Jeon, E. J.; Jindariani, S.; Jones, M.; Joo, K. K.; Jun, S. Y.; Junk, T. R.; Kambeitz, M.; Kamon, T.; Karchin, P. E.; Kasmi, A.; Kato, Y.; Ketchum, W.; Keung, J.; Kilminster, B.; Kim, D. H.; Kim, H. S.; Kim, J. E.; Kim, M. J.; Kim, S. H.; Kim, S. B.; Kim, Y. J.; Kim, Y. K.; Kimura, N.; Kirby, M.; Knoepfel, K.; Kondo, K.; Kong, D. J.; Konigsberg, J.; Kotwal, A. V.; Kreps, M.; Kroll, J.; Kruse, M.; Kuhr, T.; Kurata, M.; Laasanen, A. T.; Lammel, S.; Lancaster, M.; Lannon, K.; Latino, G.; Lee, H. S.; Lee, J. S.; Leo, S.; Leone, S.; Lewis, J. D.; Limosani, A.; Lipeles, E.; Lister, A.; Liu, H.; Liu, Q.; Liu, T.; Lockwitz, S.; Loginov, A.; Lucchesi, D.; Lucá, A.; Lueck, J.; Lujan, P.; Lukens, P.; Lungu, G.; Lys, J.; Lysak, R.; Madrak, R.; Maestro, P.; Malik, S.; Manca, G.; Manousakis-Katsikakis, A.; Marchese, L.; Margaroli, F.; Marino, P.; Matera, K.; Mattson, M. E.; Mazzacane, A.; Mazzanti, P.; McNulty, R.; Mehta, A.; Mehtala, P.; Mesropian, C.; Miao, T.; Mietlicki, D.; Mitra, A.; Miyake, H.; Moed, S.; Moggi, N.; Moon, C. S.; Moore, R.; Morello, M. J.; Mukherjee, A.; Muller, Th.; Murat, P.; Mussini, M.; Nachtman, J.; Nagai, Y.; Naganoma, J.; Nakano, I.; Napier, A.; Nett, J.; Neu, C.; Nigmanov, T.; Nodulman, L.; Noh, S. Y.; Norniella, O.; Oakes, L.; Oh, S. H.; Oh, Y. D.; Oksuzian, I.; Okusawa, T.; Orava, R.; Ortolan, L.; Pagliarone, C.; Palencia, E.; Palni, P.; Papadimitriou, V.; Parker, W.; Pauletta, G.; Paulini, M.; Paus, C.; Phillips, T. J.; Piacentino, G.; Pianori, E.; Pilot, J.; Pitts, K.; Plager, C.; Pondrom, L.; Poprocki, S.; Potamianos, K.; Pranko, A.; Prokoshin, F.; Ptohos, F.; Punzi, G.; Redondo Fernández, I.; Renton, P.; Rescigno, M.; Rimondi, F.; Ristori, L.; Robson, A.; Rodriguez, T.; Rolli, S.; Ronzani, M.; Roser, R.; Rosner, J. L.; Ruffini, F.; Ruiz, A.; Russ, J.; Rusu, V.; Sakumoto, W. K.; Sakurai, Y.; Santi, L.; Sato, K.; Saveliev, V.; Savoy-Navarro, A.; Schlabach, P.; Schmidt, E. E.; Schwarz, T.; Scodellaro, L.; Scuri, F.; Seidel, S.; Seiya, Y.; Semenov, A.; Sforza, F.; Shalhout, S. Z.; Shears, T.; Shepard, P. F.; Shimojima, M.; Shochet, M.; Shreyber-Tecker, I.; Simonenko, A.; Sliwa, K.; Smith, J. R.; Snider, F. D.; Song, H.; Sorin, V.; St. Denis, R.; Stancari, M.; Stentz, D.; Strologas, J.; Sudo, Y.; Sukhanov, A.; Suslov, I.; Takemasa, K.; Takeuchi, Y.; Tang, J.; Tecchio, M.; Teng, P. K.; Thom, J.; Thomson, E.; Thukral, V.; Toback, D.; Tokar, S.; Tollefson, K.; Tomura, T.; Tonelli, D.; Torre, S.; Torretta, D.; Totaro, P.; Trovato, M.; Ukegawa, F.; Uozumi, S.; Vázquez, F.; Velev, G.; Vellidis, C.; Vernieri, C.; Vidal, M.; Vilar, R.; Vizán, J.; Vogel, M.; Volpi, G.; Wagner, P.; Wallny, R.; Wang, S. M.; Waters, D.; Wester, W. C.; Whiteson, D.; Wicklund, A. B.; Wilbur, S.; Williams, H. H.; Wilson, J. S.; Wilson, P.; Winer, B. L.; Wittich, P.; Wolbers, S.; Wolfe, H.; Wright, T.; Wu, X.; Wu, Z.; Yamamoto, K.; Yamato, D.; Yang, T.; Yang, U. K.; Yang, Y. C.; Yao, W.-M.; Yeh, G. P.; Yi, K.; Yoh, J.; Yorita, K.; Yoshida, T.; Yu, G. B.; Yu, I.; Zanetti, A. M.; Zeng, Y.; Zhou, C.; Zucchelli, S.; CDF Collaboration

    2015-11-01

    We study charged particle production (pT>0.5 GeV /c , |η |<0.8 ) in proton-antiproton collisions at total center-of-mass energies √{s }=300 GeV , 900 GeV, and 1.96 TeV. We use the direction of the charged particle with the largest transverse momentum in each event to define three regions of η -ϕ space: "toward", "away", and "transverse." The average number and the average scalar pT sum of charged particles in the transverse region are sensitive to the modeling of the "underlying event." The transverse region is divided into a MAX and MIN transverse region, which helps separate the "hard component" (initial and final-state radiation) from the "beam-beam remnant" and multiple parton interaction components of the scattering. The center-of-mass energy dependence of the various components of the event is studied in detail. The data presented here can be used to constrain and improve QCD Monte Carlo models, resulting in more precise predictions at the LHC energies of 13 and 14 TeV.

  13. FAD-dependent lysine-specific demethylase-1 regulates cellular energy expenditure.

    PubMed

    Hino, Shinjiro; Sakamoto, Akihisa; Nagaoka, Katsuya; Anan, Kotaro; Wang, Yuqing; Mimasu, Shinya; Umehara, Takashi; Yokoyama, Shigeyuki; Kosai, Ken-Ichiro; Nakao, Mitsuyoshi

    2012-03-27

    Environmental factors such as nutritional state may act on the epigenome that consequently contributes to the metabolic adaptation of cells and the organisms. The lysine-specific demethylase-1 (LSD1) is a unique nuclear protein that utilizes flavin adenosine dinucleotide (FAD) as a cofactor. Here we show that LSD1 epigenetically regulates energy-expenditure genes in adipocytes depending on the cellular FAD availability. We find that the loss of LSD1 function, either by short interfering RNA or by selective inhibitors in adipocytes, induces a number of regulators of energy expenditure and mitochondrial metabolism such as PPARγ coactivator-1α resulting in the activation of mitochondrial respiration. In the adipose tissues from mice on a high-fat diet, expression of LSD1-target genes is reduced, compared with that in tissues from mice on a normal diet, which can be reverted by suppressing LSD1 function. Our data suggest a novel mechanism where LSD1 regulates cellular energy balance through coupling with cellular FAD biosynthesis.

  14. Dependence on temperature and energy of the heteroepitaxy of small metallic nanoclusters.

    PubMed

    Jiménez-Sáez, J C; Pérez-Martín, A M C; Jiménez-Rodríguez, J J

    2011-10-01

    Deposition at different energies and temperatures of small metallic nanoclusters on metallic substrates is studied by molecular-dynamics simulations. Small-, Co/Cu(001), and large-misfit, Cu/Au(001) and Au/Cu(001), systems are considered. The rise in temperature improves the epitaxial order, although its effect is smaller in large-misfit systems. Thus, by increasing this parameter, non-epitaxial clusters can turn their structure into epitaxial in the case of Co/Cu(001), into aligned in Cu/Au(001), and into layered in Au/Cu(001). Therefore, the characteristics of the alignment are determined by the properties of the material. In addition, the influence of the initial structure is more marked in Co and Cu clusters, since they can reproduce locally other phases. Epitaxy can also be improved if the deposition energy<