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Sample records for absorption calorimeter tac

  1. Determination of the total absorption peak in an electromagnetic calorimeter

    NASA Astrophysics Data System (ADS)

    Cheng, Jia-Hua; Wang, Zhe; Lebanowski, Logan; Lin, Guey-Lin; Chen, Shaomin

    2016-08-01

    A physically motivated function was developed to accurately determine the total absorption peak in an electromagnetic calorimeter and to overcome biases present in many commonly used methods. The function is the convolution of a detector resolution function with the sum of a delta function, which represents the complete absorption of energy, and a tail function, which describes the partial absorption of energy and depends on the detector materials and structures. Its performance was tested with the simulation of three typical cases. The accuracy of the extracted peak value, resolution, and peak area was improved by an order of magnitude on average, relative to the Crystal Ball function.

  2. Determination of global absorptivity and emissivity of some opaque bulk materials using an integrating sphere calorimeter without ports

    NASA Astrophysics Data System (ADS)

    Ochieng, Reccab M.; Onyango, Frederick N.; Owino, Albert J.

    2007-08-01

    A design of a calorimeter based on the principle of an integrating sphere for the determination of thermal absorptance, α, and emittance, ɛ, of opaque bulk materials is presented. A transient technique based on the sample heating and cooling histories is employed in this work. Arrays of four thermocouples used as temperature sensors on the sample within the integrating sphere are interfaced to a thermal card on a Fluke-2286/5 data logger. Two of the thermocouples measure the average ambient temperature inside the sphere, whereas the other two thermocouples are used to obtain an average value of the temperature of the sample. The use of an 'integrating sphere calorimeter' configuration results in much simpler heat balance equations within the enclosure as opposed to other methods which take into consideration convective and radiative heat coefficients (Kola et al 1995 Meas. Sci. Technol. 6 888-92, Otieno et al 1997 Meas. Sci. Technol. 8 239-44). When solved analytically, the equations return thermophysical values which are in good agreement with values obtained using other methods and calorimeter configurations. The experimental results obtained from our 'integrating sphere' calorimeter show that the absorptance for aluminium is α = 0.100 and its emittance is ɛ = 0.176. For copper α = 0.325, ɛ = 0.240. These values compare well with other known experimental values of α = 0.099 and ɛ = 0.174 for aluminium and α = 0.349 and ɛ = 0.246 for copper respectively (Kola et al 1995 Meas. Sci. Technol. 6 888-92, Otieno et al 1997 Meas. Sci. Technol. 8 239-44). Our values are much closer to values obtained using standard techniques (Jaworske 1994 Thin Solid Films 253 233-7, http://www.sheldahl.com).

  3. GLD Calorimeter

    NASA Astrophysics Data System (ADS)

    Takeshita, Tohru

    2006-10-01

    The GLD calorimeter, which is under study to aim as the calorimeter of ILC detector with an idea of Particle Flow, is described and discussed. The calorimeter consists of ECAL and HCAL. Both calorimeters are composed of plastic scintillator as the active medium. Fine granularity is required to achieve Particle Flow, so a small scintillator tile technique is developed with wavelength shifting fiber of MPPC read out. The requirements and our solutions for them are discussed and presented.

  4. TACS Central Control Facility.

    DTIC Science & Technology

    1981-02-12

    Central Control Facility 6 3. System Management Data Flow 7 B. Hardware Operating Environment 9 1. Computer 9 2. TACS Interfaces 9 3. Other Central...TERMINATION TIMING 131 Appendix C SYSTEM MANAGEMENT DATA FORMATS 135 Appendix D FIVE- AND NINE-SLOT SYSTEM IMPLEMENTATION DIFFERENCES 147 Appendix E...control burst management ) 26 2-7 Call Progress Messages 29 2-8 Flowchart of Assignment/Blockage Decision Process for All-Member Net Requests 30 2-9

  5. TacNet Tracker Software

    SciTech Connect

    WISEMAN, JAMES; & STEVENS, JAMES

    2008-08-04

    The TacNet Tracker will be used for the monitoring and real-time tracking of personnel and assets in an unlimited number of specific applications. The TacNet Tracker software is a VxWorks Operating System based programming package that controls the functionality for the wearable Tracker. One main use of the TacNet Tracker is in Blue Force Tracking, the ability to track the good guys in an adversarial situation or in a force-on-force or real battle conditions. The purpose of blue force tracking is to provide situational awareness to the battlefield commanders and personnel. There are practical military applications with the TacNet Tracker.The mesh network is a wireless IP communications network that moves data packets from source IP addresses to specific destination IP addresses. Addresses on the TacNet infrastructure utilize an 8-bit network mask (255.0.0.0). In other words, valid TacNet addresses range from 10.0.0.1 to 10.254.254.254. The TacNet software design uses uni-cast transmission techniques because earlier mesh network software releases did not provide for the ability to utilize multi-cast data movement. The TacNet design employs a list of addresses to move information within the TacNet infrastructure. For example, a convoy text file containing the IP addresses of all valid receivers of TacNet information could be used for transmitting the information and for limiting transmission to addresses on the list.

  6. Photon Calorimeter

    DOEpatents

    Chow, Tze-Show

    1989-01-01

    A photon calorimeter (20, 40) is provided that comprises a laminar substrate (10, 22, 42) that is uniform in density and homogeneous in atomic composition. A plasma-sprayed coating (28, 48, 52), that is generally uniform in density and homogeneous in atomic composition within the proximity of planes that are parallel to the surfaces of the substrate, is applied to either one or both sides of the laminar substrate. The plasma-sprayed coatings may be very efficiently spectrally tailored in atomic number. Thermocouple measuring junctions (30, 50, 54) are positioned within the plasma-sprayed coatings. The calorimeter is rugged, inexpensive, and equilibrates in temperature very rapidly.

  7. Photon calorimeter

    DOEpatents

    Chow, Tze-Show

    1988-04-22

    A photon calorimeter is provided that comprises a laminar substrate that is uniform in density and homogeneous in atomic composition. A plasma-sprayed coating, that is generally uniform in density and homogeneous in atomic composition within the proximity of planes that are parallel to the surfaces of the substrate, is applied to either one or both sides of the laminar substrate. The plasma-sprayed coatings may be very efficiently spectrally tailored in atomic number. Thermocouple measuring junctions, are positioned within the plasma-sprayed coatings. The calorimeter is rugged, inexpensive, and equilibrates in temperature very rapidly. 4 figs.

  8. The 2007 TAC SCM Prediction Challenge

    NASA Astrophysics Data System (ADS)

    Pardoe, David; Stone, Peter

    The TAC SCM Prediction Challenge presents an opportunity for agents designed for the full TAC SCM game to compete solely on their ability to make predictions. Participants are presented with situations from actual TAC SCM games and are evaluated on their prediction accuracy in four categories: current and future computer prices, and current and future component prices. This paper introduces the Prediction Challenge and presents the results from 2007 along with an analysis of how the predictions of the participants compare to each other.

  9. 50 CFR 665.211 - Total Allowable Catch (TAC) limit.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Total Allowable Catch (TAC) limit. 665.211... Fisheries § 665.211 Total Allowable Catch (TAC) limit. (a) TAC limits will be set annually for the fishing... Administrator shall publish a notice indicating the annual TAC limit in the Federal Register by August 31...

  10. The PHENIX electromagnetic calorimeter

    SciTech Connect

    Kistenev, E.; White, S.; Belikov, S.; Kochetkov, V.

    1993-12-31

    The main features of the Phenix EM calorimeter are presented. This a Pb/scintillator calorimeter with ``shish-kebab`` fiber readout, designed for low energy electron and photon measurements. Prototype calorimeters have been built with longitudinal segmentation, {approximately} 100 psec time of flight resolution and 8% energy resolution at 1GeV/c. The laser based monitoring system which has been incorporated into large scale prototypes is described. The dependence of light yield on fiber choice and scintillator surface preparation has been studied.

  11. Tic Tac Toe Math. Train the Trainer.

    ERIC Educational Resources Information Center

    Center for Alternative Learning, Bryn Mawr, PA.

    This report describes a project that developed a "Train the Trainer" program that would enable individuals to learn and teach the alternative instructional technique, Tic Tac Toe Math, developed by Richard Cooper for adult basic education students. The pilot workshop conducted as part of the project identified problems that traditional…

  12. Tic Tac Toe Math. Instructional Guide.

    ERIC Educational Resources Information Center

    Cooper, Richard

    This instructional guide and set of three companion workbooks are intended for use in an arithmetic course based on the Tic Tac Toe method of addition and multiplication, which is an alternative means of learning to add and multiply that was developed for students whose learning disabilities (including difficulty in distinguishing left from right…

  13. TAC Serendipity: Random Thoughts on Unanticipated Outcomes.

    ERIC Educational Resources Information Center

    Yap, Kim Onn

    The primary function of the Title I Technical Assistance Center (TAC) was to facilitate the implementation of the Title I Evaluation and Reporting System (TIERS) in local school districts by providing technical assistance in evaluation to state education agency and local education agency personnel involved in Title I activities. However,…

  14. Local Evaluation Use: Can the TAC Help?

    ERIC Educational Resources Information Center

    Hansen, Joe B.

    Interviews were conducted with contact persons in each of six Western states to assist in determining how the services and products of the Elementary and Secondary Education Act Title I Evaluation Technical Assistance Centers (TAC) could be used most effectively to help State and local education agencies improve the use and usefulness of…

  15. Magnetically Coupled Calorimeters

    NASA Technical Reports Server (NTRS)

    Bandler, Simon

    2011-01-01

    Calorimeters that utilize the temperature sensitivity of magnetism have been under development for over 20 years. They have targeted a variety of different applications that require very high resolution spectroscopy. I will describe the properties of this sensor technology that distinguish it from other low temperature detectors and emphasize the types of application to which they appear best suited. I will review what has been learned so far about the best materials, geometries, and read-out amplifiers and our understanding of the measured performance and theoretical limits. I will introduce some of the applications where magnetic calorimeters are being used and also where they are in development for future experiments. So far, most magnetic calorimeter research has concentrated on the use of paramagnets to provide temperature sensitivity; recent studies have also focused on magnetically coupled calorimeters that utilize the diamagnetic response of superconductors. I will present some of the highlights of this research, and contrast the properties of the two magnetically coupled calorimeter types.

  16. 48 CFR 1201.301-72 - TAC or TN numbering.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false TAC or TN numbering. 1201... FEDERAL ACQUISITION REGULATIONS SYSTEM Agency Acquisition Regulations 1201.301-72 TAC or TN numbering. TACs and TNs will be numbered consecutively on a fiscal year basis beginning with number “01”...

  17. 50 CFR 648.201 - Closures and TAC controls.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Closures and TAC controls. 648.201 Section... Atlantic Herring Fishery § 648.201 Closures and TAC controls. (a) If NMFS determines that catch will reach 95 percent of the annual TAC allocated to a management area before the end of the fishing year, or...

  18. The ATLAS Tile Calorimeter

    SciTech Connect

    Henriques, A.

    2015-07-01

    TileCal is the Hadronic calorimeter covering the most central region of the ATLAS experiment at the LHC. It uses iron plates as absorber and plastic scintillating tiles as the active material. Scintillation light produced in the tiles is transmitted by wavelength shifting fibres to photomultiplier tubes (PMTs). The resulting electronic signals from the approximately 10000 PMTs are measured and digitised every 25 ns before being transferred to off-detector data-acquisition systems. This contribution will review in a first part the performances of the calorimeter during run 1, obtained from calibration data, and from studies of the response of particles from collisions. In a second part it will present the solutions being investigated for the ongoing and future upgrades of the calorimeter electronics. (authors)

  19. Overview of the TAC-BIO sensor

    NASA Astrophysics Data System (ADS)

    Cabalo, Jerry; Sickenberger, Richard; De Lucia, Marla; Briles, John; Poldmae, Aime; Sickenberger, David

    2005-05-01

    In light of the current state of detection technologies designed to meet the current threat from biological agents, the need for a low-cost and lightweight sensor is clear. Such a sensor based on optical detection, with real time responses and no consumables, is possible. Devices arising from the Defense Advanced Research Projects Agency's (DARPA) Semiconductor UV Optical Sources (SUVOS) are the enabling technology. These sources are capable of emitting UV wavelengths known to excite fluorescence from biological agent particles while costing a few dollars apiece and consuming low power. These devices are exploited in the TAC-Bio Sensor. A unique optical design is used to collect the usable portion of the LED emission and focus it into the probing region of the sensor. To compensate for the low UV power density relative to UV lasers, the TAC-Bio utilizes a unique opposed flow configuration to increase the interaction between particles and the UV beam. The current TAC-Bio sensor testbed is capable of detecting fluorescence Bacillus globigii (BG, an anthrax simulant) spore agglomerates down to 5 microns in diameter. Ongoing work is focusing on increasing signal to noise so that smaller particles, possibly single spores, can be detected, as well as on including additional data channels, such as light scattering, to increase selectivity of the sensor.

  20. MAC calorimeters and applications

    SciTech Connect

    MAC Collaboration

    1982-03-01

    The MAC detector at PEP features a large solid-angle electromagnetic/hadronic calorimeter system, augmented by magnetic charged-particle tracking, muon analysis and scintillator triggering. Its implementation in the context of electron-positron annihilation physics is described, with emphasis on the utilization of calorimetry.

  1. An Inexpensive Solution Calorimeter

    ERIC Educational Resources Information Center

    Kavanagh, Emma; Mindel, Sam; Robertson, Giles; Hughes, D. E. Peter

    2008-01-01

    We describe the construction of a simple solution calorimeter, using a miniature bead thermistor as a temperature-sensing element. This has a response time of a few seconds and made it possible to carry out a thermometric reaction in under a minute, which led to minimal heat losses. Small temperature changes of 1 K associated with enthalpies of…

  2. Tac-beta1 inhibits FAK activation and Src signaling.

    PubMed

    Berrier, Allison L; Jones, Christopher W; LaFlamme, Susan E

    2008-03-28

    The binding of integrins to extracellular matrix triggers signals that promote cell spreading. We previously demonstrated that expression of the integrin beta1 cytoplasmic domain in the context of a chimeric transmembrane receptor with the Tac subunit of the interleukin-2 receptor (Tac-beta1) inhibits cell spreading. To study the mechanism whereby Tac-beta1 inhibits cell spreading, we examined the effect of Tac-beta1 on early signaling events following integrin engagement namely FAK and Src signaling. We infected primary fibroblasts with adenoviruses expressing Tac or Tac-beta1 and found that Tac-beta1 prevented FAK activation by inhibiting the phosphorylation of FAK at Tyr-397. In contrast, Src activation was maintained, as phosphorylation of Src at Tyr-419 and Tyr-530 were not responsive to expression of Tac-beta1. Importantly, adhesion-induced tyrosine phosphorylation of the Src substrates p130Cas and paxillin was inhibited, indicating that Src signaling was blocked by Tac-beta1. These Src-dependent signaling events were found to require FAK signaling. Our results suggest that Tac-beta1 inhibits cell spreading, at least in part, by preventing the phosphorylation of FAK at Tyr-397 and the assembly of signaling complexes necessary for phosphorylation of p130Cas and other downstream effectors.

  3. Secondary Emission Calorimeter (SEC)

    SciTech Connect

    Schmidt, J. J.; Northrop, Richard; Frisch, Henry; Elagin, Andrey; Ronzhin, Anatoly; Ramberg, Erik; Spiropulu, Maria; Apresyan, Artur; Xie, Si

    2014-06-25

    This is a technical scope of work (TSW) between the Fermi National Accelerator Laboratory (Fermilab) the experimenters of University of Chicago and California Institute of Technology, who have committed to participate in beam tests to be carried out during the 2014-2015 Fermilab Test Beam Facility program. The TSW is intended primarily for the purpose of recording expectations for budget estimates and work allocations. The experimenters propose using large-area micro-channel plates assembled without the usual bialkali photocathodes as the active element in sampling calorimeters, Modules without photocathodes can be economically assembled in a glove box and then pumped and sealed using the process to construct photomultipliers, This electromagnetic calorimeter is based on W and Pb absorber plates sandwiched with detectors. Measurements can be made with bare plates and absorber inside the vacuum vessel.

  4. Radionuclide calorimeter system

    DOEpatents

    Donohoue, Thomas P.; Oertel, Christopher P.; Tyree, William H.; Valdez, Joe L.

    1991-11-26

    A circuit for measuring temperature differentials in a calorimeter is disclosed. The temperature differential between the reference element and sample element containing a radioactive material is measured via a wheatstone bridge arrangement of thermistors. The bridge is driven with an alternating current on a pulsed basis to maintain the thermal floor of the calorimeter at a low reference value. A lock-in amplifier connected to the bridge phase locks a signal from the bridge to the input pulsed AC signal to provide a DC voltage. The DC voltage is sampled over time and provided to a digital computer. The digital computer, using curve fitting algorithms, will derive a function for the sample data. From the function, an equilibrium value for the temperature may be calculated.

  5. Radionuclide calorimeter system

    DOEpatents

    Donohoue, T.P.; Oertel, C.P.; Tyree, W.H.; Valdez, J.L.

    1991-11-26

    A circuit for measuring temperature differentials in a calorimeter is disclosed. The temperature differential between the reference element and sample element containing a radioactive material is measured via a Wheatstone bridge arrangement of thermistors. The bridge is driven with an alternating current on a pulsed basis to maintain the thermal floor of the calorimeter at a low reference value. A lock-in amplifier connected to the bridge phase locks a signal from the bridge to the input pulsed AC signal to provide a DC voltage. The DC voltage is sampled over time and provided to a digital computer. The digital computer, using curve fitting algorithms, will derive a function for the sample data. From the function, an equilibrium value for the temperature may be calculated. 7 figures.

  6. The HPS electromagnetic calorimeter

    DOE PAGES

    Balossino, I.; Baltzell, N.; Battaglieri, M.; ...

    2017-02-22

    The Heavy Photon Search experiment (HPS) is searching for a new gauge boson, the so-called "heavy photon". Through its kinetic mixing with the Standard Model photon, this particle could decay into an electron-positron pair. It would then be detectable as a narrow peak in the invariant mass spectrum of such pairs, or, depending on its lifetime, by a decay downstream of the production target. The HPS experiment is installed in Hall-B of Jefferson Lab. This article presents the design and performance of one of the two detectors of the experiment, the electromagnetic calorimeter, during the runs performed in 2015-2016. The calorimeter's main purpose is to provide a fast trigger and reduce the copious background from electromagnetic processes through matching with a tracking detector. Finally, the detector is a homogeneous calorimeter, made of 442 lead-tungsten (PbWOmore » $$_4$$) scintillating crystals, each read-out by an avalanche photodiode coupled to a custom trans-impedance amplifier.« less

  7. DSWA calorimeter bomb experiments

    SciTech Connect

    Cunningham, B

    1998-10-01

    Two experiments were performed in which 25 grams of TNT were detonated inside an expended detonation calorimeter bomb. The bomb had a contained volume of approximately 5.28 liters. In the first experiment, the bomb was charged with 3 atmospheres of nitrogen. In the second, it was charged with 2.58 atmospheres (23.1 psi gage) of oxygen. In each experiment pressure was monitored over a period of approximately 1200 microseconds after the pulse to the CDU. Monitoring was performed via two 10,000 psi 102AO3 PCB high frequency pressure transducers mounted symmetrically in the lid of the calorimeter bomb. Conditioners used were PCB 482As. The signals from the transducers were recorded in digital format on a multi channel Tektronix scope. The sampling frequency was 10 Mhz (10 samples per microsecond). After a period of cooling following detonation, gas samples were taken and were subsequently submitted for analysis using gas mass spectrometry. Due to a late request for post shot measurement, it was only possible to make a rough estimate of the weight of debris (carbon) remaining in the calorimeter bomb following the second experiment.

  8. A theoretical study of the potential energy curves and spectroscopic constants of TaC and TaC +

    NASA Astrophysics Data System (ADS)

    Majumdar, D.; Balasubramanian, K.

    1998-02-01

    Potential energy curves for the various low-lying electronic states of TaC and TaC + have been studied using the complete active space multiconfiguration self-consistent field method (CASMCSCF) followed by first-order and restricted second-order configuration (FOCI, SOCI) interaction calculations. The effect of spin-orbit interactions has been studied using the relativistic configuration interaction method. The ground state of TaC has been found to be 2Σ + whereas two nearly degenerate states ( 1Σ +, 3Σ +) are found as candidates for the ground state of TaC +. Inclusion of spin-orbit effect yields a state 1/2 as the ground state of TaC, while in case of TaC + 1 and 0 - states are very close in energy.

  9. Advanced Thin Ionization Calorimeter (ATIC)

    NASA Technical Reports Server (NTRS)

    Wefel, John P.

    1998-01-01

    This is the final report for NASA grant NAGW-4577, "Advanced Thin Ionization Calorimeter (ATIC)". This grant covered a joint project between LSU and the University of Maryland for a Concept Study of a new type of fully active calorimeter to be used to measure the energy spectra of very high energy cosmic rays, particularly Hydrogen and Helium, to beyond 1014 eV. This very high energy region has been studied with emulsion chamber techniques, but never investigated with electronic calorimeters. Technology had advanced to the point that a fully active calorimeter based upon Bismuth Germanate (BGO) scintillating crystals appeared feasible for balloon flight (and eventually space) experiments.

  10. Proportional wire calorimeter for magnet pole tips

    SciTech Connect

    Kraus, D; Ludlam, T; Renardy, J; Willis, W; Zurfluh, E

    1980-01-01

    A total absorption calorimeter is designed to have magnetic properties comparable to those of ordinary steel, and thus can be incorporated into the poles of a spectrometer magnet without compromising the field quality. A test device has been built which consists of an iron structure penetrated by a finegrain pattern of holes, each acting as a proportional tube such that 90% of the volume is occupied by iron. Measurements of the energy and space resolution of this device in a high energy beam will be presented.

  11. Information and Library Programs at the Technology Application Center (TAC).

    ERIC Educational Resources Information Center

    Burch, Eugene

    The Technology Application Center (TAC) at the University of New Mexico is one of six National Aeronautics and Space Administration (NASA) regional dissemination centers originally established to disseminate NASA technology to private industry on a regional basis. A fee is charged for TAC's services so it has been market oriented and has sought to…

  12. Electromagnetic calorimeter for Belle II

    NASA Astrophysics Data System (ADS)

    Belle-ECL; Aulchenko, V.; Bobrov, A.; Bondar, A.; Cheon, B. G.; Eidelman, S.; Epifanov, D.; Garmash, Yu; Goh, Y. M.; Kim, S. H.; Krokovny, P.; Kuzmin, A.; Lee, I. S.; Matvienko, D.; Miyabayashi, K.; Nakamura, I.; Shebalin, V.; Shwartz, B.; Unno, Y.; Usov, Yu; Vinokurova, A.; Vorobjev, V.; Zhilich, V.; Zhulanov, V.

    2015-02-01

    The electromagnetic calorimeter of the BELLE II detector for experiments at Super B-factory SuperKEKB is briefly described. The project of the calorimeter upgrade to meet severe background conditions expected at the upgraded KEK B factory is presented.

  13. Turkish Accelerator Center (TAC) Project: Status and Regional Importance

    SciTech Connect

    Yavas, Oe.

    2010-01-21

    The Turkish Accelerator Center (TAC) Project was started in 1997 with support of the State Planning Organization (SPO) of Turkey under Ankara University's coordination. After completing Feasibility Report (FR, 2000) and Conceptual Design Repot (CDR, 2005), third phase of the project was started in 2006 as an inter-university project with support of SPO. Third phase of the project has two main scientific goals: to write Technical Design Report (TDR) of TAC and to establish an Infrared Free Electron Laser (IR FEL) facility as a first step. The first facility and TDR studies are planned to be completed in 2012. Construction phase of TAC will cover 2013-2023. TAC collaboration include ten Turkish Universities: Ankara, Gazi, Istanbul, Bogazici, Dogus, Uludag, Dumlupmar, Nigde, Erciyes and S. Demirel Universities. It was planned that the first facility will be an IR FEL and Bremsstrahlung laboratory based on 15-40 MeV electron linac and two optical cavities with 2.5 and 9 cm undulators to scan 2-250 microns wavelength range. Main purpose of the facility is to use IR FEL for research in material science, nonlinear optics, semiconductors, biotechnology, medicine and photochemical processes. In this study; aims, regional importance, main parts and main parameters of TAC and TAC IR FEL and Bremsstrahlung facility are explained. Road map of the TAC project is given. National and international collaborations are explained.

  14. Turkish Accelerator Center (TAC) Project: Status and Regional Importance

    NASA Astrophysics Data System (ADS)

    Yavaş, Ö.

    2010-01-01

    The Turkish Accelerator Center (TAC) Project was started in 1997 with support of the State Planning Organization (SPO) of Turkey under Ankara University's coordination. After completing Feasibility Report (FR, 2000) and Conceptual Design Repot (CDR, 2005), third phase of the project was started in 2006 as an inter-university project with support of SPO. Third phase of the project has two main scientific goals: to write Technical Design Report (TDR) of TAC and to establish an Infrared Free Electron Laser (IR FEL) facility as a first step. The first facility and TDR studies are planned to be completed in 2012. Construction phase of TAC will cover 2013-2023. TAC collaboration include ten Turkish Universities: Ankara, Gazi, İstanbul, Boğaziçi, Doğuş, Uludağ, Dumlupmar, Niğde, Erciyes and S. Demirel Universities. It was planned that the first facility will be an IR FEL & Bremsstrahlung laboratory based on 15-40 MeV electron linac and two optical cavities with 2.5 and 9 cm undulators to scan 2-250 microns wavelength range. Main purpose of the facility is to use IR FEL for research in material science, nonlinear optics, semiconductors, biotechnology, medicine and photochemical processes. In this study; aims, regional importance, main parts and main parameters of TAC and TAC IR FEL & Bremsstrahlung facility are explained. Road map of the TAC project is given. National and international collaborations are explained.

  15. Research on calorimeter for high-power microwave measurements

    SciTech Connect

    Ye, Hu; Ning, Hui; Yang, Wensen; Tian, Yanmin; Xiong, Zhengfeng; Yang, Meng; Yan, Feng; Cui, Xinhong

    2015-12-15

    Based on measurement of the volume increment of polar liquid that is a result of heating by absorbed microwave energy, two types of calorimeters with coaxial capacitive probes for measurement of high-power microwave energy are designed in this paper. The first is an “inline” calorimeter, which is placed as an absorbing load at the end of the output waveguide, and the second is an “offline” calorimeter that is placed 20 cm away from the radiation horn of the high-power microwave generator. Ethanol and high density polyethylene are used as the absorbing and housing materials, respectively. Results from both simulations and a “cold test” on a 9.3 GHz klystron show that the “inline” calorimeter has a measurement range of more than 100 J and an energy absorption coefficient of 93%, while the experimental results on a 9.3 GHz relativistic backward-wave oscillator show that the device’s power capacity is approximately 0.9 GW. The same experiments were also carried out for the “offline” calorimeter, and the results indicate that it can be used to eliminate the effects of the shock of the solenoid on the measurement curves and that the device has a higher power capacity of 2.5 GW. The results of the numerical simulations, the “cold tests,” and the experiments show good agreement.

  16. Research on calorimeter for high-power microwave measurements

    NASA Astrophysics Data System (ADS)

    Ye, Hu; Ning, Hui; Yang, Wensen; Tian, Yanmin; Xiong, Zhengfeng; Yang, Meng; Yan, Feng; Cui, Xinhong

    2015-12-01

    Based on measurement of the volume increment of polar liquid that is a result of heating by absorbed microwave energy, two types of calorimeters with coaxial capacitive probes for measurement of high-power microwave energy are designed in this paper. The first is an "inline" calorimeter, which is placed as an absorbing load at the end of the output waveguide, and the second is an "offline" calorimeter that is placed 20 cm away from the radiation horn of the high-power microwave generator. Ethanol and high density polyethylene are used as the absorbing and housing materials, respectively. Results from both simulations and a "cold test" on a 9.3 GHz klystron show that the "inline" calorimeter has a measurement range of more than 100 J and an energy absorption coefficient of 93%, while the experimental results on a 9.3 GHz relativistic backward-wave oscillator show that the device's power capacity is approximately 0.9 GW. The same experiments were also carried out for the "offline" calorimeter, and the results indicate that it can be used to eliminate the effects of the shock of the solenoid on the measurement curves and that the device has a higher power capacity of 2.5 GW. The results of the numerical simulations, the "cold tests," and the experiments show good agreement.

  17. The CDF miniplug calorimeters

    SciTech Connect

    Lami, Stefano

    2002-06-28

    Two MiniPlug calorimeters, designed to measure the energy and lateral position of particles in the (forward) pseudorapidity region of 3.6 < |{nu}| < 5.2 of the CDF detector, have been recently installed as part of the Run II CDF upgrade at the Tevatron {bar p}p collider. They consist of lead/liquid scintillator read out by wavelength shifting fibers arranged in a pixel-type towerless geometry suitable for ''calorimetric tracking''. The design concept, the prototype performance and the final design of the MiniPlugs are here described. A recent cosmic ray test resulted in a light yield of approximately 100 pe/MIP, which exceeds our design requirements.

  18. Double beta decay: Calorimeters

    NASA Astrophysics Data System (ADS)

    Brofferio, Chiara

    2008-11-01

    Calorimeters or, with a more specific definition, low temperature detectors, have been used by now for more than 15 years in Double Beta Decay (DBD) searches, with excellent results: they compete with Ge diodes for the rank of detectors with the highest sensitivity to the effective neutrino mass, which is defined as a linear combination of the neutrino mass eigenvalues. After a brief introduction to the argument, with some notes on DBD and on bolometers, an update on the now closed experiment CUORICINO and on its successor, CUORE, is given. The fundamental role of background is then revealed and commented, introducing in this way the importance of the specific experiment now under construction, CUORE-0, that will precede CUORE to help optimizing the struggle against surface background. The possible future of this technique is then commented, quoting important R&D studies that are going on, for active shielding bolometers and for scintillating bolometers coupled with light detecting bolometers.

  19. Cerenkov fiber sampling calorimeters

    SciTech Connect

    Arrington, K.; Kefford, D.; Kennedy, J.; Pisani, R.; Sanzeni, C.; Segall, K.; Wall, D.; Winn, D.R. ); Carey, R.; Dye, S.; Miller, J.; Sulak, L.; Worstell, W. ); Efremenko, Y.; Kamyshkov, Y.; Savin, A.; Shmakov, K.; Tarkovsky, E. )

    1994-08-01

    Clear optical fibers were used as a Cerenkov sampling media in Pb (electromagnetic) and Cu (hadron) absorbers in spaghetti calorimeters, for high rate and high radiation dose experiments, such as the forward region of high energy colliders. The fiber axes were aligned close to the direction of the incident particles (1[degree]--7[degree]). The 7 [lambda] deep hadron tower contained 2.8% by volume 1.5 mm diameter core clear plastic fibers. The 27 radiation length deep electromagnetic towers had packing fractions of 6.8% and 7.2% of 1 mm diameter core quartz fibers as the active Cerenkov sampling medium. The energy resolution on electrons and pions, energy response, pulse shapes and angular studies are presented.

  20. A study on dual readout crystal calorimeter for hadron and jet energy measurement at a future lepton collider

    SciTech Connect

    Yeh, G.P.; /Fermilab

    2010-01-01

    Studies of requirements and specifications of crystals are necessary to develop a new generation of crystals for dual readout crystal hadron or total absorption calorimeter. This is a short and basic study of the characteristics and hadron energy measurement of PbWO4 and BGO crystals for scintillation and Cerenkov Dual Readout hadron calorimeter.

  1. The Arabidopsis TAC Position Viewer: a high-resolution map of transformation-competent artificial chromosome (TAC) clones aligned with the Arabidopsis thaliana Columbia-0 genome.

    PubMed

    Hirose, Yoshitsugu; Suda, Kunihiro; Liu, Yao-Guang; Sato, Shusei; Nakamura, Yukino; Yokoyama, Koji; Yamamoto, Naoki; Hanano, Shigeru; Takita, Eiji; Sakurai, Nozomu; Suzuki, Hideyuki; Nakamura, Yasukazu; Kaneko, Takakazu; Yano, Kentaro; Tabata, Satoshi; Shibata, Daisuke

    2015-09-01

    We present a high-resolution map of genomic transformation-competent artificial chromosome (TAC) clones extending over all Arabidopsis thaliana (Arabidopsis) chromosomes. The Arabidopsis genomic TAC clones have been valuable genetic tools. Previously, we constructed an Arabidopsis genomic TAC library consisting of more than 10,000 TAC clones harboring large genomic DNA fragments extending over the whole Arabidopsis genome. Here, we determined 13,577 end sequences from 6987 Arabidopsis TAC clones and mapped 5937 TAC clones to precise locations, covering approximately 90% of the Arabidopsis chromosomes. We present the large-scale data set of TAC clones with high-resolution mapping information as a Java application tool, the Arabidopsis TAC Position Viewer, which provides ready-to-go transformable genomic DNA clones corresponding to certain loci on Arabidopsis chromosomes. The TAC clone resources will accelerate genomic DNA cloning, positional walking, complementation of mutants and DNA transformation for heterologous gene expression.

  2. High density fluoride glass calorimeter

    NASA Astrophysics Data System (ADS)

    Xie, Q.; Scheltzbaum, J.; Akgun, U.

    2014-04-01

    The unprecedented radiation levels in current Large Hadron Collider runs, and plans to even increase the luminosity creates a need for new detector technologies to be investigated. Quartz plates to replace the plastic scintillators in current LHC calorimeters have been proposed in recent reports. Quartz based Cherenkov calorimeters can solve the radiation damage problem, however light production and transfer have proven to be challenging. This report summarizes the results from a computational study on the performance of a high-density glass calorimeter. High-density, scintillating, fluoride glass, CHG3, was used as the active material. This glass has been developed specifically for hadron collider experiments, and is known for fast response time, in addition to high light yield. Here, the details of a Geant4 model for a sampling calorimeter prototype with 20 layers, and its hadronic as well as electromagnetic performances are reported.

  3. Electromagnetic Calorimeter for Hades Experiment

    NASA Astrophysics Data System (ADS)

    Kugler, A.; Blume, C.; Czyžycki, W.; Epple, E.; Fabbietti, L.; Galatyuk, T.; Golubeva, M.; Guber, F.; Hlaváč, S.; Ivashkin, A.; Kajetanowic, M.; Kardan, B.; Koenig, W.; Lapidus, K.; Lisowski, E.; Pietraszko, J.; Reshetin, A.; Rost, A.; Salabura, P.; Sobolev, Y. G.; Svoboda, O.; Tlusty, P.; Traxler, M.

    2014-06-01

    Electromagnetic calorimeter (ECAL) is being developed to complement the dilepton spectrometer HADES currently operating at GSI Darmstadt, Germany. ECAL will enable the HADES@FAIR experiment to measure data on neutral meson production in heavy ion collisions at the energy range of 2-10 A GeV on the beam of future accelerator SIS100@FAIR. The calorimeter will also improve the electron-hadron separation and will as well be used for the detection of photons from strange resonances in elementary and heavy ion reactions. Calorimeter modules constructed of lead glass Cherenkov counter, photomultiplier, HV divider and optical fiber are described in the detail. Two prototypes of novel front-end electronics based on TRB3 are presented. A dedicated LED based system being developed to monitor the stability of the calorimeter during beamtime is introduced as well.

  4. Design of a microwave calorimeter for the microwave tokamak experiment

    SciTech Connect

    Marinak, M. )

    1988-10-07

    The initial design of a microwave calorimeter for the Microwave Tokamak Experiment is presented. The design is optimized to measure the refraction and absorption of millimeter rf microwaves as they traverse the toroidal plasma of the Alcator C tokamak. Techniques utilized can be adapted for use in measuring high intensity pulsed output from a microwave device in an environment of ultra high vacuum, intense fields of ionizing and non-ionizing radiation and intense magnetic fields. 16 refs.

  5. Transient Calorimeter Calibration System

    DTIC Science & Technology

    1975-03-01

    can withstand the high heat flux levels encountered during calibration. 3 d. The verification of absorptivity of a colloidal graphite coat- ing used...CC4-)Ŕ ýz- ix w- Vj m ~ CL 4) > r- 4-) r-)W *. M 0 0 a 4) u.) . CJ C4) Lfl 𔃺 4%. C6 0) 0 ~ 4 -0 E 36 The colloidal graphite remains the most...before and after exposure. Such tests performed with the colloidal graphite coating yielded no apparent change in absorptivity up through 5 kW/cm2 . In

  6. The segmentation of hadron calorimeters

    NASA Astrophysics Data System (ADS)

    Chen, He Sheng

    1987-05-01

    Optimization of the segmentation of large hadron calorimeters is important in order to obtain good resolution for jet physics at minimum construction cost for the next generation of high energy experiments. The principles of the segmentation of hadron calorimeters are discussed. As an example, the Monte Carlo optimization of the segmentation of the L3 hadron calorimeter barrel at CERN is described. Comparisons of results for the reconstructed jet shapes show that the optimum number ADC channels is about 20K for the readout of 450K wires of the proportional chambers. The matching between the sandwiched φ towers and Z towers is the dominant factor for angular resolution. Based on these Monte Carlo simulations, an optimized tower structure is obtained.

  7. Precision Timing Calorimeter for High Energy Physics

    DOE PAGES

    Anderson, Dustin; Apresyan, Artur; Bornheim, Adolf; ...

    2016-04-01

    Here, we present studies on the performance and characterization of the time resolution of LYSO-based calorimeters. Results for an LYSO sampling calorimeter and an LYSO-tungsten Shashlik calorimeter are presented. We also demonstrate that a time resolution of 30 ps is achievable for the LYSO sampling calorimeter. Timing calorimetry is described as a tool for mitigating the effects due to the large number of simultaneous interactions in the high luminosity environment foreseen for the Large Hadron Collider.

  8. COE1 Calorimeter Operations Manual

    SciTech Connect

    Santi, Peter Angelo

    2015-12-15

    The purpose of this manual is to describe the operations of the COE1 calorimeter which is used to measure the thermal power generated by the radioactive decay of plutonium-bearing materials for the purposes of assaying the amount of plutonium within the material.

  9. LHCb calorimeters high voltage system

    NASA Astrophysics Data System (ADS)

    Gilitsky, Yu.; Golutvin, A.; Konoplyannikov, A.; Lefrancois, J.; Perret, P.; Schopper, A.; Soldatov, M.; Yakimchuk, V.

    2007-02-01

    The calorimeter system in LHCb aims to identify electrons, photons and hadrons. All calorimeters are equipped with Hamamatsu photo tubes as devices for light to signal conversion. Eight thousand R7899-20 tubes are used for electromagnetic and hadronic calorimeters and two hundred 64 channels multi-anode R7600-00-M64 for Scintillator-Pad/Preshower detectors. The calorimeter high voltage (HV) system is based on a Cockroft Walton (CW) voltage converter and a control board connected to the Experiment Control System (ECS) by serial bus. The base of each photomultiplier tube (PMT) is built with a high voltage converter and constructed on an individual printed circuit board, using compact surface mount components. The base is attached directly to the PMT. There are no HV cables in the system. A Field Programmable Gate Array (FPGA) is used on the control board as an interface between the ECS and the 200 control channels. The FPGA includes also additional functionalities allowing automated monitoring and ramp up of the high voltage values. This paper describes the HV system architecture, some technical details of the electronics implementation and summarizes the system performance. This safe and low power consumption HV electronic system for the photomultiplier tubes can be used for various biomedical apparatus too.

  10. Barrel calorimeter of the CMD-3 detector

    SciTech Connect

    Shebalin, V. E. Anisenkov, A. V.; Aulchenko, V. M.; Bashtovoy, N. S.; Epifanov, D. A.; Epshteyn, L. B.; Grebenuk, A. A.; Ignatov, F. V.; Erofeev, A. L.; Kovalenko, O. A.; Kozyrev, A. N.; Kuzmin, A. S.; Logashenko, I. B.; Mikhailov, K. Yu.; Razuvaev, G. P.; Ruban, A. A.; Shwartz, B. A.; Talyshev, A. A.; Titov, V. M.; Yudin, Yu. V.

    2015-12-15

    The structure of the barrel calorimeter of the CMD-3 detector is presented in this work. The procedure of energy calibration of the calorimeter and the method of photon energy restoration are described. The distinctive feature of this barrel calorimeter is its combined structure; it is composed of two coaxial subsystems: a liquid xenon calorimeter and a crystalline CsI calorimeter. The calorimeter spatial resolution of the photon conversion point is about 2 mm, which corresponds to an angular resolution of ∼6 mrad. The energy resolution of the calorimeter is about 8% for photons with energy of 200 MeV and 4% for photons with energy of 1 GeV.

  11. Evaluation of the ECIA Chapter 1 Technical Assistance Centers (TACs).

    ERIC Educational Resources Information Center

    Reisner, Elizabeth; And Others

    This study evaluated the national network of Technical Assistance Centers (TACs), which provides technical assistance in evaluation and program improvement to state and local educational agencies responsible for implementing programs under Chapter 1 of the Education Consolidation and Improvement Act (ECIA). The U.S. Department of Education…

  12. PILOT STUDY: THE TAMPA ASTHMATIC CHILDREN'S STUDY (TACS)

    EPA Science Inventory

    The Tampa Asthmatic Children's Study (TACS) was a pilot research study that focused on developing and evaluating air pollution exposure assessment methods and participant recruiting tools for children in the age range of 1-5 years old. The pilot study focused on (a) simple, cost-...

  13. EXPOSURE ASSESSMENT FINDINGS FROM THE TAMPA ASTHMATIC CHILDREN'S STUDY (TACS)

    EPA Science Inventory

    The Tampa Asthmatic Children's Study (TACS) was a pilot study that focused on developing and evaluating air pollution exposure assessment methods and participant recruiting tools. The four-week study was performed in October and November, 2003. The study involved repeated daily...

  14. 50 CFR 665.211 - Total Allowable Catch (TAC) limit.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 50 Wildlife and Fisheries 11 2011-10-01 2011-10-01 false Total Allowable Catch (TAC) limit. 665.211 Section 665.211 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND... of, Hawaii Restricted Bottomfish Species by vessels legally registered to Mau Zone, Ho`omalu Zone,...

  15. CsI Calorimeter for a Compton-Pair Telescope

    NASA Astrophysics Data System (ADS)

    Grove, Eric J.

    We propose to build and test a hodoscopic CsI(Tl) scintillating-crystal calorimeter for a medium-energy γ-ray Compton and pair telescope. The design and technical approach for this calorimeter relies deeply on heritage from the Fermi LAT CsI Calorimeter, but it dramatically improves the low-energy performance of that design by reading out the scintillation light with silicon photomultipliers (SiPMs), making the technology developed for Fermi applicable in the Compton regime. While such a hodoscopic calorimeter is useful for an entire class of medium-energy γ-ray telescope designs, we propose to build it explicitly to support beam tests and balloon flight of the Proto-ComPair telescope, the development and construction of which was funded in a four-year APRA program beginning in 2015 ("ComPair: Steps to a Medium Energy γ-ray Mission" with PI J. McEnery of GSFC). That award did not include funding for its CsI calorimeter subsystem, and this proposal is intended to cover that gap. ComPair is a MIDEX-class instrument concept to perform a high-sensitivity survey of the γ-ray sky from 0.5 MeV to 500 MeV. ComPair is designed to provide a dramatic increase in sensitivity relative to previous instruments in this energy range (predominantly INTEGRAL/SPI and Compton COMPTEL), with the same transformative sensitivity increase – and corresponding scientific return– that the Fermi Large Area Telescope provided relative to Compton EGRET. To enable transformative science over a broad range of MeV energies and with a wide field of view, ComPair is a combined Compton telescope and pair telescope employing a silicon-strip tracker (for Compton scattering and pair conversion and tracking) and a solid-state CdZnTe calorimeter (for Compton absorption) and CsI calorimeter (for pair calorimetry), surrounded by a plastic scintillator anti-coincidence detector. Under the current proposal, we will complete the detailed design, assembly, and test of the CsI calorimeter for the risk

  16. The CLAS Forward Electromagnetic Calorimeter

    SciTech Connect

    M. Amarian; Geram Asryan; Kevin Beard; Will Brooks; Volker Burkert; Tom Carstens; Alan Coleman; Raphael Demirchyan; Yuri Efremenko; Hovanes Egiyan; Kim Egiyan; Herb Funsten; Vladimir Gavrilov; Kevin L. Giovanetti; R.M. Marshall; Berhard Mecking; R.C. Minehart; H. Mkrtchan; Mavrik Ohandjanyan; Youri Sharabian; L.C. Smith; Stepan Stepanyan; W.A. Stephens; T.Y. Tung; Carl Zorn

    2001-05-01

    The CEBAF Large Acceptance Spectrometer (CLAS) at Jefferson Lab utilizes six iron-free superconducting coils to provide an approximately toroidal magnetic field. The six sectors are instrumented individually to form six independent spectrometers. The forward region (8deg < (theta) < 45deg) of each sector is equipped with a lead-scintillator electromagnetic sampling calorimeter (EC), 16 radiation lengths thick, using a novel triangular geometry with stereo readout. With its good energy and position resolution, the EC is used to provide the primary electron trigger for CLAS. It is also used to reject pions, reconstruct pi-0 and eta decays and detect neutrons, This paper treats the design, construction and performance of the calorimeter.

  17. Compensation effects in hadron calorimeters

    SciTech Connect

    Gabriel, T.A.; Bishop, B.L.; Brau, J.; Di Ciaccio, A.; Goodman, M.; Wilson, R.

    1984-01-01

    The pros and cons of utilizing a fissionable material such as /sup 238/U to compensate for the nuclear binding energy losses in a hadron calorimeter are discussed. Fissionable material can return some lost energy to the particle cascade in terms of low-energy neutrons and gamma rays, but electromagnetic sampling inefficiencies (often called transition effects) and the detection medium which tries to convert this energy to a useable signal are just as important. 12 references.

  18. Electromagnetic Calorimeter for HADES Experiment

    NASA Astrophysics Data System (ADS)

    Rodríguez-Ramos, P.; Chlad, L.; Epple, E.; Fabbietti, L.; Galatyuk, T.; Golubeva, M.; Guber, F.; Hlaváč, S.; Ivashkin, A.; Kajetanowic, M.; Kardan, B.; Koenig, W.; Korcyl, G.; Kugler, A.; Lapidus, K.; Linev, S.; Lisowski, E.; Neiser, A.; Ott, O.; Otte, O.; Pethukov, O.; Pietraszko, J.; Reshetin, A.; Rost, A.; Salabura, P.; Sobolev, Y. G.; Svoboda, O.; Thomas, A.; Tlusty, P.; Traxler, M.

    2014-11-01

    Electromagnetic calorimeter (ECAL) is being developed to complement dilepton spectrometer HADES. ECAL will enable the HADES@FAIR experiment to measure data on neutral meson production in heavy ion collisions at the energy range of 2-10 AGeV on the beam of future accelerator SIS100@FAIR. We will report results of the last beam test with quasi-monoenergetic photons carried out in MAMI facility at Johannes Gutenberg Universität Mainz.

  19. An elevated temperature titration calorimeter

    SciTech Connect

    Smith, J.R.; Zanonato, P.L.; Choppin, G.R. . Dept. of Chemistry)

    1991-06-01

    A variable-temperature (313 K to 353 K) titration calorimeter of high sensitivity has been constructed. The purpose of the calorimeter is to study temperature effects on the enthalpies of complex formation and of other reactions of metal cations such as hydrolysis and precipitation. Operation of the calorimetric system, including that final calculation of the heat released during titration, is automatic via computer control. Calibration tests of the calorimeter using 2-amino-2-hydroxymethyl-1,3-propanediol gave -(46.0 {plus minus} 0.3) kJ mol{sup {minus}1} and -(46.2 {plus minus} 0.2) kJ mol{sup {minus}1} for the enthalpy of protonation, at 318 K and at 343 K, respectively. For titrations of 2-bis(2-hydroxyethyl) amino-2-hydroxymethyl-1,3-propanediol, enthalpy of protonation values of -(28.4 {plus minus} 0.3) kJ mol{sup {minus}1} and -(29.3 {plus minus} 0.2) kJ mol{sup {minus}1} were obtained at 318 K and at 343 K, respectively. 6 refs., 3 figs., 2 tabs.

  20. Secondary Emission Calorimeter Sensor Development

    NASA Astrophysics Data System (ADS)

    Winn, David R.; Onel, Yasar

    2012-12-01

    In a Secondary Emission electron(SEe) detector module, Secondary Emission electrons (SEe) are generated from an SE surface/cathode, when charged hadronic or electromagnetic particles, particularly shower particles, penetrate an SE sampling module placed between absorber materials (Fe, Cu, Pb, W etc) in calorimeters. The SE cathode is a thin (10-50 nm thick) film (simple metal-oxides, or other higher yield materials) on the surface of a metal plate, which serves as the entrance “window” to a compact vacuum vessel (metal or metal-ceramic); this SE film cathode is analogous to a photocathode, and the SEe are similar to p.e., which are then amplified by dynodes, also is in a PMT. SE sensor modules can make use of electrochemically etched/machined or laser-cut metal mesh dynode sheets, as large as ~30 cm square, to amplify the Secondary Emission Electrons (SEe), much like those that compact metal mesh or mesh dynode PMT's use to amplify p.e.'s. The construction requirements easier than a PMT, since the entire final assembly can be done in air; there are no critical controlled thin film depositions, cesiation or other oxygen-excluded processes or other required vacuum activation, and consequently bake-out can be a refractory temperatures; the module is sealed by normal vacuum techniques (welding or brazing or other high temperature joinings), with a simple final heated vacuum pump-out and tip-off. The modules envisioned are compact, high gain, high speed, exceptionally radiation damage resistant, rugged, and cost effective, and can be fabricated in arbitrary tileable shapes. The SE sensor module anodes can be segmented transversely to sizes appropriate to reconstruct electromagnetic cores with high precision. The GEANT4 and existing calorimeter data estimated calorimeter response performance is between 35-50 Secondary Emission electrons per GeV, in a 1 cm thick Cu absorber calorimeter, with a gain per SEe > 105 per SEe, and an e/pi<1.2. The calorimeter pulse width is

  1. Mechanical Design of the DAMPE BGO Calorimeter

    NASA Astrophysics Data System (ADS)

    Hu, Yiming; Wu, Jian; Feng, Changqing; Zhang, Yunlong; Chen, Dengyi; Chang, Jin

    The Dark Matter Particle Explorer, DAMPE, is a new designed satellite developed for the CASs new Innovation 2020 program. As the main component of DAMPE, the new designed BGO calorimeter consists of 308 BGO Crystals coupled with photomultiplier tube.The reliability and safety of the BGO Calorimeter structure play a very important role in the operation of whole detector. During the rocket launch, the calorimeter structure should be stable against vibration and environmental factors to ensure detector works in good conditions. In this article, we make the BGO calorimeter structure design, and then prove that it will work in the environments of rocket launch and flight.

  2. Ordering Effects in NbC and TaC

    NASA Technical Reports Server (NTRS)

    Venables, J. D.; Meyerhoff, M. H.

    1972-01-01

    By means of transmission electron microscopy and electron diffraction, evidence has been obtained for the existence of long range carbon atom ordering in single-crystal niobium carbide that has a carbon-to-metal ratio close to the integral composition Nb6C5. The ordering, which gives rise to superlattice and domain structures similar to those observed in V6C5, appears, however, only in samples that have been cooled slowly through the order-disorder temperature of 1025 C. In TaC of similar composition, the ordering, although present, remains very imperfect even after the crystals are subjected to the same thermal treatment. The results are interpreted in terms of the electronic structure of the transition metal carbides as it is currently understood, and their relevance to the mechanical properties of NbC and TaC are discussed.

  3. Drawing strategies for generalized tic-tac-toe (p, q)

    NASA Astrophysics Data System (ADS)

    Diptarama, Narisawa, Kazuyuki; Shinohara, Ayumi

    2016-02-01

    GTTT(p, q) is an achievement game for polyominoes, which is an extension of Harary's generalized tic-tac-toe. Two players alternately put p stones over a board with the exception that the first player Black puts q stones for the first move. The player who first achieves a given polyomino wins the game. Unlike the generalized tic-tac-toe, we define winner for polyomino that Black can achieve, loser that White can achieve, and draw that both players cannot achieve in each GTTT(p, q). In this paper we define three classes of polyominoes for GTTT(p, q) and show that any polyomino that satisfies some conditions for each classes is a draw.

  4. Automatic TAC extraction from dynamic cardiac PET imaging using iterative correlation from a population template.

    PubMed

    Mateos-Pérez, José M; Desco, Manuel; Dae, Michael W; García-Villalba, Carmen; Cussó, Lorena; Vaquero, Juan J

    2013-08-01

    This work describes a new iterative method for extracting time-activity curves (TAC) from dynamic imaging studies using a priori information from generic models obtained from TAC templates. Analytical expressions of the TAC templates were derived from TACs obtained by manual segmentation of three (13)NH3 pig studies (gold standard). An iterative method for extracting both ventricular and myocardial TACs using models of the curves obtained as an initial template was then implemented and tested. These TACs were extracted from masked and unmasked images; masking was applied to remove the lungs and surrounding non-relevant structures. The resulting TACs were then compared with TACs obtained manually; the results of kinetic analysis were also compared. Extraction of TACs for each region was sensitive to the presence of other organs (e.g., lungs) in the image. Masking the volume of interest noticeably reduces error. The proposed method yields good results in terms of TAC definition and kinetic parameter estimation, even when the initial TAC templates do not accurately match specific tracer kinetics.

  5. AN/TAC-1 demultiplexer circuit card assembly

    NASA Astrophysics Data System (ADS)

    Krueger, Paul J.

    1989-01-01

    This report describes the design, operation, and testing of the AN/TAC-1 demultiplexer subassembly. It demultiplexes the 6144 kb/s digital data stream received over fiber optic cable or tropo satellite support radio, and converts it into 2 digital groups and 16 digital channels. Timing recovery is accomplished by generating a 18432 kHz master clock synchronized to the incoming data. This master clock is divided modulo two to generate the proper group and loop timing.

  6. ATLAS liquid argon calorimeter front end electronics

    NASA Astrophysics Data System (ADS)

    Buchanan, N. J.; Chen, L.; Gingrich, D. M.; Liu, S.; Chen, H.; Damazio, D.; Densing, F.; Duffin, S.; Farrell, J.; Kandasamy, S.; Kierstead, J.; Lanni, F.; Lissauer, D.; Ma, H.; Makowiecki, D.; Muller, T.; Radeka, V.; Rescia, S.; Ruggiero, R.; Takai, H.; Wolniewicz, K.; Ghazlane, H.; Hoummada, A.; Hervas, L.; Hott, T.; Wilkens, H. G.; Ban, J.; Boettcher, S.; Brooijmans, G.; Chi, C.-Y.; Caughron, S.; Cooke, M.; Copic, K.; Dannheim, D.; Gara, A.; Haas, A.; Katsanos, I.; Parsons, J. A.; Simion, S.; Sippach, W.; Zhang, L.; Zhou, N.; Eckstein, P.; Kobel, M.; Ladygin, E.; Auge, E.; Bernier, R.; Bouchel, M.; Bozzone, A.; Breton, D.; de la Taille, C.; Falleau, I.; Fournier, D.; Imbert, P.; Martin-Chassard, G.; Perus, A.; Richer, J. P.; Seguin Moreau, N.; Serin, L.; Tocut, V.; Veillet, J.-J.; Zerwas, D.; Colas, J.; Dumont-Dayot, N.; Massol, N.; Perrodo, P.; Perrot, G.; Wingerter-Seez, I.; Escalier, M.; Hubaut, F.; Laforge, B.; LeDortz, O.; Schwemling, Ph; Collot, J.; Dzahini, D.; Gallin-Martel, M.-L.; Martin, P.; Cwienk, W. D.; Fent, J.; Kurchaninov, L.; Citterio, M.; Mazzanti, M.; Tartarelli, F.; Bansal, V.; Boulahouache, C.; Cleland, W.; Liu, B.; McDonald, J.; Paolone, V.; Rabel, J.; Savinov, V.; Zuk, G.; Benslama, K.; Borgeaud, P.; de la Broïse, X.; Delagnes, E.; LeCoguie, A.; Mansoulié, B.; Pascual, J.; Teiger, J.; Dinkespiler, B.; Liu, T.; Stroynowski, R.; Ye, J.; Zarzhitsky, P.; Grahn, K.-J.; Hansson, P.; Lund-Jensen, B.; Chu, M. L.; Lee, S.-C.; Su, D. S.; Teng, P. K.; Braun, H. M.

    2008-09-01

    The ATLAS detector has been designed for operation at CERN's Large Hadron Collider. ATLAS includes a complex system of liquid argon calorimeters. This paper describes the architecture and implementation of the system of custom front end electronics developed for the readout of the ATLAS liquid argon calorimeters.

  7. 5.8 X-ray Calorimeters

    NASA Technical Reports Server (NTRS)

    Porter, F. Scott

    2008-01-01

    X-ray calorimeter instruments for astrophysics have seen rapid development since they were invented in 1984. The prime instrument on all currently planned X-ray spectroscopic observatories is based on calorimeter technology. This relatively simple detection concept that senses the energy of an incident photon by measuring the temperature rise of an absorber material at very low temperatures, can form the basis of a very high performance, non-dispersive spectrometer. State-of-the-art calorimeter instruments have resolving powers of over 3000, large simultaneous band-passes, and near unit efficiency. This coupled with the intrinsic imaging capability of a pixilated x-ray calorimeter array, allows true spectral-spatial instruments to be constructed. In this chapter I briefly review the detection scheme, the state-of-the-art in X-ray calorimeter instruments and the future outlook for this technology.

  8. A Novel Tiller Angle Gene, TAC3, together with TAC1 and D2 Largely Determine the Natural Variation of Tiller Angle in Rice Cultivars

    PubMed Central

    Dong, Haijiao; Zhao, Hu; Xie, Weibo; Han, Zhongmin; Li, Guangwei; Yao, Wen; Bai, Xufeng; Hu, Yong; Guo, Zilong; Lu, Kai; Yang, Lin; Xing, Yongzhong

    2016-01-01

    Tiller angle is one of the most important components of the ideal plant architecture that can greatly enhance rice grain yield. Understanding the genetic basis of tiller angle and mining favorable alleles will be helpful for breeding new plant-type varieties. Here, we performed genome-wide association studies (GWAS) to identify genes controlling tiller angle using 529 diverse accessions of Oryza sativa including 295 indica and 156 japonica accessions in two environments. We identified 7 common quantitative trait loci (QTLs), including the previously reported major gene Tiller Angle Control 1 (TAC1), in the two environments, 10 and 13 unique QTLs in Hainan and Wuhan, respectively. More QTLs were identified in indica than in japonica, and three major QTLs (qTA3, qTA1b/DWARF2 (D2) and qTA9c/TAC1) were fixed in japonica but segregating in indica, which explained the wider variation observed in indica compared with that in japonica. No common QTLs were identified between the indica and japonica subpopulations. Mutant analysis for the candidate gene of qTA3 on chromosome 3 indicated a novel gene, Tiller Angle Control 3 (TAC3), encoding a conserved hypothetical protein controlling tiller angle. TAC3 is preferentially expressed in the tiller base. The ebisu dwarf (d2) mutant exhibited a decreased tiller angle, in addition to its previously described abnormal phenotype. A nucleotide diversity analysis revealed that TAC3, D2 and TAC1 have been subjected to selection during japonica domestication. A haplotype analysis identified favorable alleles of TAC3, D2 and TAC1, which may be used for breeding plants with an ideal architecture. In conclusion, there is a diverse genetic basis for tiller angle between the two subpopulations, and it is the novel gene TAC3 together with TAC1, D2, and other newly identified genes in this study that controls tiller angle in rice cultivars. PMID:27814357

  9. The evolution of tachykinin/tachykinin receptor (TAC/TACR) in vertebrates and molecular identification of the TAC3/TACR3 system in zebrafish (Danio rerio).

    PubMed

    Zhou, Wenyi; Li, Shuisheng; Liu, Yun; Qi, Xin; Chen, Huapu; Cheng, Christopher H K; Liu, Xiaochun; Zhang, Yong; Lin, Haoran

    2012-09-25

    Tachykinins are a family of peptides that are conserved from invertebrates to mammals. However, little is known about the evolutionary history of tachykinin (TAC) and tachykinin receptor (TACR) genes in vertebrates, especially in the teleost group. In the present study, five TACs and six TACRs genes were identified in the zebrafish genome. Genomic synteny analysis and phylogenetic tree analysis indicate that the increased numbers of TAC and TACR genes in vertebrates are the result of both genome duplications and local individual gene duplication. The full-length cDNA sequences encoding multiple TAC3s (TAC3a and TAC3b) and TACR3s (TACR3a1, TACR3a2 and TACR3b) were subsequently cloned from zebrafish brain samples. Sequence analysis suggested that four putative neurokinin B (NKB)-like peptides (NKBa-13, NKBa-10, NKBb-13 and NKBb-11) might be generated by the processing of two zebrafish TAC3 precursors. Tissue distribution studies in zebrafish revealed that TAC3 and TACR3 are mainly expressed in the brain regions. The biological activities of four zebrafish NKB peptides and three TACR3s were further examined using transcription reporter assays in cultured eukaryotic cells. All the synthetic NKB peptides were able to evoke the downstream signaling events of TACR3s with the exception of NKBb-11. These results indicated that the multiple TAC/TACR genes identified in vertebrates evolved from gene duplication events and that the TAC3/TACR3 systems also operate in the teleost group.

  10. Modeling Heat Flow In a Calorimeter Equipped With a Textured Solar Collector

    NASA Technical Reports Server (NTRS)

    Jaworske, Donald A.; Allen, Bradley J.

    2001-01-01

    Heat engines are being considered for generating electric power for minisatellite applications, particularly for those missions in high radiation threat orbits. To achieve this objective, solar energy must be collected and transported to the hot side of the heat engine. A solar collector is needed having the combined properties of high solar absorptance, low infrared emittance, and high thermal conductivity. To test candidate solar collector concepts, a simple calorimeter was designed, manufactured, and installed in a bench top vacuum chamber to measure heat flow. In addition, a finite element analysis model of the collector/calorimeter combination was made to model this heat flow. The model was tuned based on observations from the as-manufactured collector/calorimeter combination. In addition, the model was exercised to examine other collector concepts, properties, and scale up issues.

  11. The Development of a 3D Imaging Calorimeter of DAMPE for Cosmic Ray Physics

    NASA Astrophysics Data System (ADS)

    Zhang, Yunlong; Hu, Yiming; Feng, Changqing; Liu, Shubin; Wang, Chi; Zhang, Zhiyong; Wei, Yifeng; Huang, Guangshun

    2016-07-01

    The DArk Matter Particle Explorer (DAMPE) experiment began its on-orbit operations on December 17, 2015. The BGO Electromagnetic Calorimeter (BGO ECAL) of the DAMPE is a total absorption calorimeter that allows for a precise three-dimensional imaging of the shower shape. It provides a good energy resolution (<1%@200GeV) and high electron/hadron discrimination (>10^5). The calorimeter also provides a trigger capability to DAMPE. The BGO ECAL light collection system and electronics are designed to measure electromagnetic particles over a wide energy range, from 5 GeV to 10 TeV. An Engineering qualified model was built and tested using high energy electron and proton beams with energy ranging from 1 GeV to 250GeV. Some pre results will be introduced in this talk.

  12. TaC Studios New Construction Test House

    SciTech Connect

    Butler, T.; Curtis, O.; Kim, E.; Roberts, S.; Stephenson, R.

    2013-03-01

    As part of the NAHB Research Center Industry Partnership, Southface partnered with TaC Studios, an Atlanta based architecture firm specializing in residential and light commercial design, on the construction of a new test home in Atlanta, GA in the mixed humid climate zone. This home will serve as a model home for the builder partner and addresses Building America energy savings targets through the planning and implementation of a design package will serve as a basis of design for the builder partner's future homes. As a BA test house, this home will be evaluated to detail whole house energy use, end use loads, and HVAC and hot water efficiency.

  13. TaC Studios New Construction Test House

    SciTech Connect

    Butler, T.; Curtis, O.; Kim, E.; Roberts, S.; Stephenson, R.

    2013-03-01

    As part of the NAHB Research Center Industry Partnership, Southface partnered with TaC Studios, an Atlanta based architecture firm specializing in residential and light commercial design, on the construction of a new test home in Atlanta, GA, in the mixed humid climate zone. This home will serve as a model home for the builder partner and addresses Building America energy savings targets through the planning and implementation of a design package will serve as a basis of design for the builder partner’s future homes. As a BA test house, this home will be evaluated to detail whole house energy use, end use loads, and HVAC and hot water efficiency.

  14. Spectrophotometric assays for total antioxidant capacity (TAC) in dog serum: an update.

    PubMed

    Rubio, Camila Peres; Hernández-Ruiz, Josefa; Martinez-Subiela, Silvia; Tvarijonaviciute, Asta; Ceron, José Joaquin

    2016-08-15

    The aim of this review is to study the main spectrophotometric methods used to evaluate total antioxidant capacity (TAC) in serum samples of dogs. Total antioxidant capacity (TAC) is an analyte frequently used to assess the antioxidant status of biological samples and can evaluate the antioxidant response against the free radicals produced in a given disease. Trolox equivalent antioxidant capacity (TEAC), ferric reducing ability of plasma (FRAP), and cupric reducing antioxidant capacity (CUPRAC) are different assays described to determine TAC of a sample. This review explains the basis of each assay and their application in the determination of TAC in dogs, and also provides selected information about reports in humans for comparative purposes. It is concluded that, ideally, various different assays integrated in a panel should be used for TAC evaluation, since depending on the assay performed TAC results can be markedly different.

  15. Floating data acquisition system for microwave calorimeter measurements on MTX

    SciTech Connect

    Sewall, N.R.; Meassick, S. )

    1989-09-13

    A microwave calorimeter has been designed for making 140-GHz absorption measurements on the MTX. Measurement of the intensity and spatial distribution of the FEL-generated microwave beam on the inner wall will indicate the absorption characteristics of the plasma when heated with a 140 GHz FEL pulse. The calorimeter works by monitoring changes of temperature in silicon carbide tiles located on the inner wall of the tokamak. Thermistors are used to measure the temperature of each tile. The tiles are located inside the tokamak about 1 cm outside of the limiter radius at machine potential. The success of this measurement depends on our ability to float the data acquisition system near machine potential and isolate it from the rest of the vault ground system. Our data acquisition system has 48 channels of thermistor signal conditioning, a multiplexer and digitizer section, a serial data formatter, and a fiber-optic transmitter to send the data out. Additionally, we bring timing signals to the interface through optical fibers to tell it when to begin measurement, while maintaining isolation. The receiver is an HP 200 series computer with a serial data interface; the computer provides storage and local display for the shot temperature profile. Additionally, the computer provides temporary storage of the data until it can be passed to a shared resource management system for archiving. 2 refs., 6 figs.

  16. Electromagnetic transients program (EMTP): Volume 4, Workbook IV (TACS) (Transients Analysis of Control Systems): Final report

    SciTech Connect

    Lasseter, R.H.

    1989-06-01

    This workbook represents an introduction to the use of TACS (Transients Analysis of Control Systems) in the EMTP. The material progresses from an overview of basic TACS concepts and components to a detailed HVDC model. The following application of TACS are covered: a variable load problem, static Var systems, thyristor models, TCR, basic HVDC models and a detailed HVDC model. Complete data files are given for most examples.

  17. Concurrent Electroencephalography Recording During Transcranial Alternating Current Stimulation (tACS).

    PubMed

    Fehér, Kristoffer D; Morishima, Yosuke

    2016-01-22

    Oscillatory brain activities are considered to reflect the basis of rhythmic changes in transmission efficacy across brain networks and are assumed to integrate cognitive neural processes. Transcranial alternating current stimulation (tACS) holds the promise to elucidate the causal link between specific frequencies of oscillatory brain activity and cognitive processes. Simultaneous electroencephalography (EEG) recording during tACS would offer an opportunity to directly explore immediate neurophysiological effects of tACS. However, it is not trivial to measure EEG signals during tACS, as tACS creates a huge artifact in EEG data. Here we explain how to set up concurrent tACS-EEG experiments. Two necessary considerations for successful EEG recording while applying tACS are highlighted. First, bridging of the tACS and EEG electrodes via leaking EEG gel immediately saturates the EEG amplifier. To avoid bridging via gel, the viscosity of the EEG gel is the most important parameter. The EEG gel must be viscous to avoid bridging, but at the same time sufficiently fluid to create contact between the tACS electrode and the scalp. Second, due to the large amplitude of the tACS artifact, it is important to consider using an EEG system with a high resolution analog-to-digital (A/D) converter. In particular, the magnitude of the tACS artifact can exceed 100 mV at the vicinity of a stimulation electrode when 1 mA tACS is applied. The resolution of the A/D converter is of importance to measure good quality EEG data from the vicinity of the stimulation site. By following these guidelines for the procedures and technical considerations, successful concurrent EEG recording during tACS will be realized.

  18. TAC-TIC use of tacrolimus-based regimens in lupus nephritis.

    PubMed

    Kraaij, Tineke; Bredewold, Obbo W; Trompet, Stella; Huizinga, Tom W J; Rabelink, Ton J; de Craen, Anton J M; Teng, Y K Onno

    2016-01-01

    Current guidelines do not mention tacrolimus (TAC) as a treatment option and no consensus has been reported on the role of TAC in lupus nephritis (LN). The present study aimed to guide clinical judgement on the use of TAC in patients with LN. A meta-analysis was performed for clinical studies investigating TAC regimens in LN on the basis of treatment target (induction or maintenance), concomitant immunosuppression and quality of the data. 23 clinical studies performed in patients with LN were identified: 6 case series, 9 cohort studies, 2 case-control studies and 6 randomised controlled trials (RCTs). Of the 6 RCTs, 5 RCTs investigated TAC regimens as induction treatment and 1 RCT as maintenance treatment. Five RCTs investigated TAC in combination with steroids and 2 TAC with mycophenolate plus steroids. All RCTs were performed in patients of Asian ethnicity. In a meta-analysis, TAC regimens achieved a significantly higher total response (relative risk (RR) 1.23, 95% CI 1.12 to 1.34, p<0.05) and significantly higher complete response (RR 1.48, 95% CI 1.23 to 1.77, p<0.05). The positive outcome was predominantly defined by the largest RCT investigating TAC with mycophenolate plus steroids. Regarding safety, the occurrence of leucopoenia was significantly lower, while the occurrence of increased creatine was higher. Clinical studies on TAC regimens for LN are limited to patients of Asian ethnicity and hampered by significant heterogeneity. The positive results on clinical efficacy of TAC as induction treatment in LN cannot be extrapolated beyond Asian patients with LN. Therefore, further confirmation in multiethnic, randomised trials is mandatory. Until then, TAC can be considered in selected patients with LN.

  19. TAC-TIC use of tacrolimus-based regimens in lupus nephritis

    PubMed Central

    Bredewold, Obbo W; Trompet, Stella; Huizinga, Tom W J; Rabelink, Ton J; de Craen, Anton J M; Teng, Y K Onno

    2016-01-01

    Current guidelines do not mention tacrolimus (TAC) as a treatment option and no consensus has been reported on the role of TAC in lupus nephritis (LN). The present study aimed to guide clinical judgement on the use of TAC in patients with LN. A meta-analysis was performed for clinical studies investigating TAC regimens in LN on the basis of treatment target (induction or maintenance), concomitant immunosuppression and quality of the data. 23 clinical studies performed in patients with LN were identified: 6 case series, 9 cohort studies, 2 case-control studies and 6 randomised controlled trials (RCTs). Of the 6 RCTs, 5 RCTs investigated TAC regimens as induction treatment and 1 RCT as maintenance treatment. Five RCTs investigated TAC in combination with steroids and 2 TAC with mycophenolate plus steroids. All RCTs were performed in patients of Asian ethnicity. In a meta-analysis, TAC regimens achieved a significantly higher total response (relative risk (RR) 1.23, 95% CI 1.12 to 1.34, p<0.05) and significantly higher complete response (RR 1.48, 95% CI 1.23 to 1.77, p<0.05). The positive outcome was predominantly defined by the largest RCT investigating TAC with mycophenolate plus steroids. Regarding safety, the occurrence of leucopoenia was significantly lower, while the occurrence of increased creatine was higher. Clinical studies on TAC regimens for LN are limited to patients of Asian ethnicity and hampered by significant heterogeneity. The positive results on clinical efficacy of TAC as induction treatment in LN cannot be extrapolated beyond Asian patients with LN. Therefore, further confirmation in multiethnic, randomised trials is mandatory. Until then, TAC can be considered in selected patients with LN. PMID:28123768

  20. First results from the SLD silicon calorimeters

    NASA Astrophysics Data System (ADS)

    Berridge, S. C.; Bugg, W. M.; Kroeger, R. S.; Weidemann, A. W.; White, S. L.; Brau, J. E.; Frey, R.; Furuno, K.; Huber, J.; Hwang, H.

    1992-07-01

    The small-angle calorimeters of the SLD were successfully operated during the recent SLC engineering run. The Luminosity Monitor and Small-Angle Tagger (LMSAT) covers the angular region between 28 and 68 milliradians from the beam axis, while the Medium-Angle Silicon Calorimeter (MASC) covers the 68-190 milliradian region. Both are silicon-tungsten sampling calorimeters; the LMSAT employs 23 layers of 0.86 X(sub 0) sampling, while the MASC has 10 layers of 1.74 X(sub 0) sampling. We present results from the first run of the SLC with the SLD on beamline.

  1. MARK II end cap calorimeter electronics

    SciTech Connect

    Jared, R.C.; Haggerty, J.S.; Herrup, D.A.; Kirsten, F.A.; Lee, K.L.; Olson, S.R.; Wood, D.R.

    1985-10-01

    An end cap calorimeter system has been added to the MARK II detector in preparation for its use at the SLAC Linear Collider. The calorimeter uses 8744 rectangular proportional counter tubes. This paper describes the design features of the data acquisition electronics that has been installed on the calorimeter. The design and use of computer-based test stands for the amplification and signal-shaping components is also covered. A portion of the complete system has been tested in a beam at SLAC. In these initial tests, using only the calibration provided by the test stands, a resolution of 18%/..sqrt..E was achieved.

  2. First results from the SLD silicon calorimeters

    SciTech Connect

    Berridge, S.C.; Bugg, W.M.; Kroeger, R.S.; Weidemann, A.W.; White, S.L.; Brau, J.E.; Frey, R.; Furuno, K.; Huber, J.; Hwang, H.; Park, H.; Pitts, K.T.; Zeitlin, C.J.; Gioumousis, A.; Haller, G.; Seward, P.

    1992-07-01

    The small-angle calorimeters of the SLD were successfully operated during the recent SLC engineering run. The Luminosity Monitor and Small-Angle Tagger (LMSAT) covers the angular region between 28 and 68 milliradians from the beam axis, while the Medium-Angle Silicon Calorimeter (MASC) covers the 68--190 milliradian region. Both are silicon-tungsten sampling calorimeters; the LMSAT employs 23 layers of 0.86 X{sub 0} sampling, while the MASC has 10 layers of 1.74 X{sub 0} sampling. We present results from the first run of the SLC with the SLD on beamline.

  3. End Calorimeter Warm Tube Heater

    SciTech Connect

    Primdahl, K.; /Fermilab

    1991-08-06

    The Tevatron accelerator beam tube must pass through the End Calorimeter cryostats of the D-Zero Collider Detector. Furthermore, the End Calorimeter cryostats must be allowed to roll back forty inches without interruption of the vacuum system; hence, the Tev tube must slide through the End Calorimeter cryostat as it is rolled back. The Tev pass through the End Calorimeter can actually be thought of as a cluster of concentric tubes: Tev tube, warm (vacuum vessel) tube, IS layers of superinsulation, cold tube (argon vessel), and Inner Hadronic center support tube. M. Foley generated an ANSYS model to study the heat load. to the cryostat. during collider physics studies; that is, without operation of the heater. A sketch of the model is included in the appendix. The vacuum space and superinsulation was modeled as a thermal solid, with conductivity derived from tests performed at Fermilab. An additional estimate was done. by this author, using data supplied by NR-2. a superinsulation manufacturer. The ANSYS result and hand calculation are in close agreement. The ANSYS model was modified. by this author. to incorporate the effect of the heater. Whereas the earlier model studied steady state operation only. the revised model considers the heater-off steady state mode as the initial condition. then performs a transient analysis with a final load step for time tending towards infinity. Results show the thermal gradient as a function of time and applied voltage. It should be noted that M. Foley's model was generated for one half the warm tube. implying the tube to be symmetric. In reality. the downstream connection (relative to the collision point) attachment to the vacuum shell is via several convolutions of a 0.020-inch wall bellows; hence. a nearly adiabatic boundary condition. Accordingly. the results reported in the table reflect extrapolation of the curves to the downstream end of the tube. Using results from the ANSYS analysis, that is, tube temperature and

  4. Improvement of CXCR3 ligand CXCL11/I-TAC measurement in human plasma and serum.

    PubMed

    Cremasco, Viviana; Mantelli, Barbara; Lazzarin, Adriano; Biswas, Priscilla

    2009-01-01

    The chemokine receptor CXCR3 is involved in cell trafficking dysregulation associated with several inflammatory conditions, including autoimmune and viral diseases. Downregulation of CXCR3, through binding with its ligand CXCL11 (I-TAC), represents a key mechanism in lymphocyte recruitment. Determination of circulating I-TAC can provide useful information in the investigation of inflammatory/infectious conditions. The existing commercial kit does not measure CXCL11/I-TAC in complex matrices, such as human plasma and serum, as reliably as in in vitro-generated cell culture supernatants. We here describe means which lead to an improvement of CXCL11/I-TAC measurement in human plasma and serum.

  5. Surface characterisation of Ga+ ion implanted ta-C thin films

    NASA Astrophysics Data System (ADS)

    Berova, M.

    2017-01-01

    Samples of thin film (d∼40nm) tetrahedral amorphous carbon (ta-C), deposited by filtered cathodic vacuum arc (FCVA), have been implanted with Ga+ at ion energy E = 20 keV and ion doses D=3.1014÷3.1015 cm-2. The induced structural modification of the implanted material results in a considerable change of its optical properties, best manifested by a significant shift of the optical absorption edge to lower photon energies. This shift is accompanied by a considerable increase of the absorption coefficient (photo-darkening effect) in the measured photon energy range (0.5÷3.0 eV). These effects could be attributed both to additional defect introduction and increased graphitization, as well as due to Ga colloids formation, as confirmed by electron microscopy analysis. Further nano-scale structural and electronic properties characterisation of the Ga+ implanted films has been carried out here using conductive atomic force microscopy (C-AFM) measurements. The observed properties modification results from the high concentration of introduced Ga+ atoms, which is of the order of those for the host element. The obtained optical contrast (between implanted and unimplanted film material) could be made use of in the area of high-density optical data storage by using focused Ga+ ion beams.

  6. Upgrading the ATLAS fast calorimeter simulation

    NASA Astrophysics Data System (ADS)

    Hubacek, Z.; ATLAS Collaboration

    2016-10-01

    Many physics and performance studies with the ATLAS detector at the Large Hadron Collider require very large samples of simulated events, and producing these using the full Geant4 detector simulation is highly CPU intensive. Often, a very detailed detector simulation is not needed, and in these cases fast simulation tools can be used to reduce the calorimeter simulation time. In ATLAS, a fast simulation of the calorimeter systems was developed, called Fast Calorimeter Simulation (FastCaloSim). It provides a parametrized simulation of the particle energy response at the calorimeter read-out cell level. It is interfaced to the standard ATLAS digitization and reconstruction software and can be tuned to data more easily than Geant4. An improved parametrization is being developed, to eventually address shortcomings of the original version. It makes use of statistical techniques such as principal component analysis and a neural network parametrization to optimise the amount of information to store in the ATLAS simulation infrastructure.

  7. CDF End Plug calorimeter Upgrade Project

    SciTech Connect

    Apollinari, G.; de Barbaro, P.; Mishina, M.

    1994-01-01

    We report on the status of the CDF End Plug Upgrade Project. In this project, the CDF calorimeters in the end plug and the forward regions will be replaced by a single scintillator based calorimeter. After an extensive R&D effort on the tile/fiber calorimetry, we have now advanced to a construction phase. We review the results of the R&D leading to the final design of the calorimeters and the development of tooling devised for this project. The quality control program of the production of the electromagnetic and hadronic calorimeters is described. A shower maximum detector for the measurement of the shower centroid and the shower profile of electrons, {gamma} and {pi}{sup 0} has been designed. Its performance requirements, R&D results and mechanical design are discussed.

  8. The BaBar electromagnetic calorimeter

    SciTech Connect

    Stahl, A.

    1997-07-01

    The progress on the design and construction of the BaBar electromagnetic calorimeter including its mechanical structure, the readout system, the mechanical and optical properties of the crystals, and the schedule for the final assembly and testing is summarized.

  9. Accelerator Test of an Imaging Calorimeter

    NASA Technical Reports Server (NTRS)

    Christl, Mark J.; Adams, James H., Jr.; Binns, R. W.; Derrickson, J. H.; Fountain, W. F.; Howell, L. W.; Gregory, J. C.; Hink, P. L.; Israel, M. H.; Kippen, R. M.; Whitaker, Ann F. (Technical Monitor)

    2001-01-01

    The Imaging Calorimeter for ACCESS (ICA) utilizes a thin sampling calorimeter concept for direct measurements of high-energy cosmic rays. The ICA design uses arrays of small scintillating fibers to measure the energy and trajectory of the produced cascades. A test instrument has been developed to study the performance of this concept at accelerator energies and for comparison with simulations. Two test exposures have been completed using a CERN test beam. Some results from the accelerator tests are presented.

  10. TAC-TIC therapy with premature infants: a series of investigative studies.

    PubMed

    de Róiste, Aine

    2004-12-01

    This article provides a synopsis of a series of studies exploring the effects of TAC-TIC (Touching And Caressing-Tender In Caring) therapy with premature infants. Study 1 looked at the short and long-term effects and found enhanced mental development in the stroked infants at 15 months. In study 2 the physiological effects of an abbreviated version of TAC-TIC with high-risk ventilated infants were examined and it was concluded that TAC-TIC exerted no harm to these vulnerable infants. The behavioural reactions of a sample of premature and low birthweight infants to TAC-TIC and parental responses to administering it were explored in study 3. The infants were found to respond predominantly with arm and leg movements to TAC-TIC while fathers and mothers reported enjoying performing TAC-TIC and elicited a similar pattern and frequency of behavioural reactions. In study 4 the question of whether TAC-TIC benefits preterm infant learning and/or sucking behaviour was investigated. The conclusion reached was that TAC-TIC may potentially benefit cognitive performance within the neonatal period and that this may be an early indicator of long-term cognitive gains reported by previous studies. Using a matched subjects design, study 5 explored the impact of TAC-TIC upon the digestive system by analysing gastric aspirates before and after TAC-TIC and a control period of time. It was concluded that TAC-TIC appeared to induce a more suitable stomach environment for digestion.

  11. ERα in Tac2 Neurons Regulates Puberty Onset in Female Mice.

    PubMed

    Greenwald-Yarnell, Megan L; Marsh, Courtney; Allison, Margaret B; Patterson, Christa M; Kasper, Chelsea; MacKenzie, Alexander; Cravo, Roberta; Elias, Carol F; Moenter, Suzanne M; Myers, Martin G

    2016-04-01

    A variety of data suggest that estrogen action on kisspeptin (Kiss1)-containing arcuate nucleus neurons (which coexpress Kiss1, neurokinin B (the product of Tac2) and dynorphin (KNDy) neurons restrains reproductive onset and function, but roles for estrogen action in these Kiss1 neurons relative to a distinct population of rostral hypothalamic Kiss1 neurons (which does not express Tac2 or dynorphin) have not been directly tested. To test the role for estrogen receptor (ER)α in KNDy cells, we thus generated Tac2(Cre) and Kiss1(Cre) knock-in mice and bred them onto the Esr1(flox) background to ablate ERα specifically in Tac2-expressing cells (ERα(Tac2)KO mice) or all Kiss1 cells (ERα(Kiss1)KO mice), respectively. Most ERα-expressing Tac2 neurons represent KNDy cells. Arcuate nucleus Kiss1 expression was elevated in ERα(Tac2)KO and ERα(Kiss1)KO females independent of gonadal hormones, whereas rostral hypothalamic Kiss1 expression was normal in ERα(Tac2)KO but decreased in ERα(Kiss1)KO females; this suggests that ERα in rostral Kiss1 cells is crucial for control of Kiss1 expression in these cells. Both ERα(Kiss1)KO and ERα(Tac2)KO females displayed early vaginal opening, early and persistent vaginal cornification, increased gonadotropins, uterine hypertrophy, and other evidence of estrogen excess. Thus, deletion of ERα in Tac2 neurons suffices to drive precocious gonadal hyperstimulation, demonstrating that ERα in Tac2 neurons typically restrains pubertal onset and hypothalamic reproductive drive.

  12. Transportable high sensitivity small sample radiometric calorimeter

    SciTech Connect

    Wetzel, J.R.; Biddle, R.S.; Cordova, B.S.; Sampson, T.E.; Dye, H.R.; McDow, J.G.

    1998-12-31

    A new small-sample, high-sensitivity transportable radiometric calorimeter, which can be operated in different modes, contains an electrical calibration method, and can be used to develop secondary standards, will be described in this presentation. The data taken from preliminary tests will be presented to indicate the precision and accuracy of the instrument. The calorimeter and temperature-controlled bath, at present, require only a 30-in. by 20-in. tabletop area. The calorimeter is operated from a laptop computer system using unique measurement module capable of monitoring all necessary calorimeter signals. The calorimeter can be operated in the normal calorimeter equilibration mode, as a comparison instrument, using twin chambers and an external electrical calibration method. The sample chamber is 0.75 in (1.9 cm) in diameter by 2.5 in. (6.35 cm) long. This size will accommodate most {sup 238}Pu heat standards manufactured in the past. The power range runs from 0.001 W to <20 W. The high end is only limited by sample size.

  13. TAC Evaluation Assistance: A Ten-Year Evolution from Accountability to Program Improvement.

    ERIC Educational Resources Information Center

    Yap, Kim O.

    The Title I/Chapter 1 Technical Assistance Centers (TACs) were originally created to provide assistance to state and local education agencies in implementing the Title I evaluation and reporting system. However, over a 10-year period, TAC role has changed significantly. Its service foci have evolved from providing evaluation assistance to helping…

  14. Test of Auditory Comprehension (TAC) for Hearing Impaired Pupils--Reliability and Validity Study.

    ERIC Educational Resources Information Center

    Hoversten, Gloria H.

    The Test of Auditory Comprehension (TAC), one component of the Auditory Skills Instructional Planning System, is a comprehensive test instrument designed for individual use with hearing impaired pupils, four through twelve years of age, for assessing receptive auditory functioning. Included in the TAC are ten discrete subtests measuring auditory…

  15. p300 is involved in formation of the TBP-TFIIA-containing basal transcription complex, TAC.

    PubMed

    Mitsiou, Dimitra J; Stunnenberg, Hendrik G

    2003-09-01

    We have recently identified a novel basal transcription complex, TAC, that is present and active in embryonal carcinoma (EC) cells but not in other adult cells such as COS7. In the search for factors involved in TAC formation, we found that expression of the adenoviral 12S E1A oncoprotein abolishes TAC formation in EC cells. This effect of E1A depends on its N-terminal domain that is essential for cell differentiation and that targets the transcriptional coactivators p300 and PCAF. Expression of p300 lacking its major E1A interaction domain, CH3, restores TAC formation in the presence of E1A, in a bromodomain- and HAT domain-dependent manner. Consistently, the unprocessed TFIIAalphabeta precursor that is selectively assembled into TAC is acetylated preferentially compared with the processed subunits present in 'free' TFIIA. Intriguingly, expression of p300 in COS7 cells that do not contain detectable levels of TAC instigates formation of TAC from endogenous components. Our data suggest that p300 plays a role in formation of the TBP-TFIIA-containing basal transcription complex, TAC.

  16. Student Groups Conducted by Teachers: The Teachers as Counselors (TAC) Program.

    ERIC Educational Resources Information Center

    Wasielewski, Raquel A.; Scruggs, Martha Y.; Scott, Carl W.

    1997-01-01

    Examines the Teachers as Counselors (TAC) program to determine student perceptions of program effectiveness, to study differential effectiveness in terms of student satisfaction, and the extent that TAC met student needs. Results indicate that the program was successful. Students with high levels of stress benefitted most from the program. (RJM)

  17. Measuring Teacher Attitudes toward Instructional Technology: A Confirmatory Factor Analysis of the TAC and TAT

    ERIC Educational Resources Information Center

    Shattuck, Dominick; Corbell, Kristen A.; Osbourne, Jason W.; Knezek, Gerald; Christensen, Rhonda; Grable, Lisa Leonor

    2011-01-01

    In this article the authors present a confirmatory factor analysis of the Teachers' Attitudes Toward Computers (TAC) and the Teachers' Attitudes Toward Information Technology (TAT) scales by Christensen and Knezek (1996, 1998) using large samples from three states. The TAC was reduced from 98 items and nine factors to 35 items and eight factors,…

  18. Monte Carlo simulation of an actual segmented calorimeter: a study of calorimeter performance at high energies

    SciTech Connect

    Gabriel, T.A.; Bishop, B.L.; Goodman, M.S.; Sessoms, A.L.; Eisenstein, B.; Wright, S.C.; Kephart, R.D.

    1981-01-01

    The calculated responses including energy resolution, angular resolution, and spatial energy deposition of a segmented iron and liquid-argon calorimeter to incident pions in the energy range of 10- to 250-GeV are presented. Experimental data for this calorimeter have been obtained in the 10- to 40- GeV energy range and these results compare favorably with the calculated data.

  19. Condor TAC: EO/IR tactical aerial reconnaissance photography system

    NASA Astrophysics Data System (ADS)

    Petrushevsky, Vladimir; Tsur, David

    2012-06-01

    Based on the experience gained with the Condor2 long-range oblique photography (LOROP) camera, ELOP is expanding its airborne reconnaissance product line with the Condor TAC tactical photography system. The latter was designed for overflight imaging of extended areas from a fighter or special mission aircraft, at day and night. The Condor TAC is mounted in an aerodynamically shaped pod and can operate in wide envelope of flight altitude and speed. Besides the camera, the pod contains mission management and video processing unit (MVU), solid state recorder (SSR), wide-band data link (DL) for real-time imagery transmission, and two environmental control units (ECU). Complex multi-segment optical windows were successfully developed for the system. The camera system design is modular and highly flexible. Two independent imaging payload modules are mounted inside a gimbal system. Each of the modules is equipped with a strap-down IMU, and may carry a cluster of cameras or a single large camera with gross weight up to 35 kg. The payload modules are interchangeable, with an identical interface to the gimbal. The modularity and open architecture of the system facilitate its adaptation to various operational requirements, as well as allow easy and relatively non-expensive upgrades and configuration changes. In the current configuration, both EO and IR payload modules are equipped with a combination of longer focal length cameras for bi-directional panoramic scan at medium and high flight altitudes, and shorter focal length cameras for fixed wide angle coverage at low altitudes. All the camera types are equipped with standard format, off-the-shelf area detector arrays. Precise motion compensation is achieved by calibrated back-scan mirrors.

  20. Development of a high resolution alpha spectrometer using a magnetic calorimeter

    NASA Astrophysics Data System (ADS)

    Yoon, W. S.; Kang, C. S.; Kim, S. R.; Kim, G. B.; Lee, H. J.; Lee, M. K.; Lee, J. H.; So, J. H.; Kim, Y. H.

    2015-06-01

    We have developed a high resolution alpha spectrometer with a magnetic calorimeter. The operating principle of the detector is the calorimetric measurement of the temperature increase from particle absorption in a gold foil absorber at milli-Kelvin temperatures. A magnetic calorimeter made of gold doped with erbium on a superconducting meander pickup coil was used to accurately measure the temperature change, thereby acting as an ultra-sensitive thermometer. The detector demonstrated 1.2 keV FWHM equivalent resolution in alpha particle detection with an 241Am source. Many peaks were observed in the low-energy region from the absorption of low-energy X-rays, gamma rays, and conversion electrons. An energy resolution of 400 eV FWHM was achieved for 60 keV gamma rays that were measured with the alpha particles. Possible applications of such high resolution detectors are discussed.

  1. Faith and oscillations recovered: On analyzing EEG/MEG signals during tACS.

    PubMed

    Neuling, Toralf; Ruhnau, Philipp; Weisz, Nathan; Herrmann, Christoph S; Demarchi, Gianpaolo

    2017-02-15

    Despite recent success in analyzing brain oscillations recorded during transcranial alternating current stimulation (tACS), the field still requires further research to establish standards in artifact removal methods. This includes taking a step back from the removal of the tACS artifact and thoroughly characterizing the to-be-removed artifact. A recent study by Noury et al. (2016) contributed importantly to this endeavour by showing the existence of nonlinear artefacts in the tACS signal as seen by MEG and EEG. Unfortunately however this paper conveys the message that current artifact removal attempts have failed altogether and that-based on these available tools-brain oscillations recorded during tACS cannot be analyzed using MEG and EEG. Here we want to balance this overly pessimistic conclusion: In-depth reanalyses of our own data and phantom-head measurements indicate that nonlinearities can occur, but only when technical limits of the stimulator are reached. As such they are part of the "real" stimulation and not a specific MEG analysis problem. Future tACS studies should consider these technical limits to avoid any nonlinear modulations of the tACS artifact. We conclude that even with current approaches, brain oscillations recorded during tACS can be meaningfully studied in many practical cases.

  2. TAC102 Is a Novel Component of the Mitochondrial Genome Segregation Machinery in Trypanosomes.

    PubMed

    Trikin, Roman; Doiron, Nicholas; Hoffmann, Anneliese; Haenni, Beat; Jakob, Martin; Schnaufer, Achim; Schimanski, Bernd; Zuber, Benoît; Ochsenreiter, Torsten

    2016-05-01

    Trypanosomes show an intriguing organization of their mitochondrial DNA into a catenated network, the kinetoplast DNA (kDNA). While more than 30 proteins involved in kDNA replication have been described, only few components of kDNA segregation machinery are currently known. Electron microscopy studies identified a high-order structure, the tripartite attachment complex (TAC), linking the basal body of the flagellum via the mitochondrial membranes to the kDNA. Here we describe TAC102, a novel core component of the TAC, which is essential for proper kDNA segregation during cell division. Loss of TAC102 leads to mitochondrial genome missegregation but has no impact on proper organelle biogenesis and segregation. The protein is present throughout the cell cycle and is assembled into the newly developing TAC only after the pro-basal body has matured indicating a hierarchy in the assembly process. Furthermore, we provide evidence that the TAC is replicated de novo rather than using a semi-conservative mechanism. Lastly, we demonstrate that TAC102 lacks an N-terminal mitochondrial targeting sequence and requires sequences in the C-terminal part of the protein for its proper localization.

  3. TAC102 Is a Novel Component of the Mitochondrial Genome Segregation Machinery in Trypanosomes

    PubMed Central

    Hoffmann, Anneliese; Haenni, Beat; Jakob, Martin; Schnaufer, Achim; Schimanski, Bernd; Zuber, Benoît; Ochsenreiter, Torsten

    2016-01-01

    Trypanosomes show an intriguing organization of their mitochondrial DNA into a catenated network, the kinetoplast DNA (kDNA). While more than 30 proteins involved in kDNA replication have been described, only few components of kDNA segregation machinery are currently known. Electron microscopy studies identified a high-order structure, the tripartite attachment complex (TAC), linking the basal body of the flagellum via the mitochondrial membranes to the kDNA. Here we describe TAC102, a novel core component of the TAC, which is essential for proper kDNA segregation during cell division. Loss of TAC102 leads to mitochondrial genome missegregation but has no impact on proper organelle biogenesis and segregation. The protein is present throughout the cell cycle and is assembled into the newly developing TAC only after the pro-basal body has matured indicating a hierarchy in the assembly process. Furthermore, we provide evidence that the TAC is replicated de novo rather than using a semi-conservative mechanism. Lastly, we demonstrate that TAC102 lacks an N-terminal mitochondrial targeting sequence and requires sequences in the C-terminal part of the protein for its proper localization. PMID:27168148

  4. Vacuum-jacketed hydrofluoric acid solution calorimeter

    USGS Publications Warehouse

    Robie, R.A.

    1965-01-01

    A vacuum-jacketed metal calorimeter for determining heats of solution in aqueous HF was constructed. The reaction vessel was made of copper and was heavily gold plated. The calorimeter has a cooling constant of 0.6 cal-deg -1-min-1, approximately 1/4 that of the air-jacketed calorimeters most commonly used with HF. It reaches equilibrium within 10 min after turning off the heater current. Measurements of the heat of solution of reagent grade KCl(-100 mesh dried 2 h at 200??C) at a mole ratio of 1 KCl to 200 H2O gave ??H = 4198??11 cal at 25??C. ?? 1965 The American Institute of Physics.

  5. Temperature Effects in the ATIC BGO Calorimeter

    NASA Technical Reports Server (NTRS)

    Isbert, J.; Adams, J. H.; Ahn, H.; Bashindzhagyan, G.; Batkov, K.; Chang, J.; Christl, M. J.; Fazely, A.; Ganel, O.; Gunasigha, R.

    2006-01-01

    The Advanced Thin Ionization Calorimeter (ATIC) Balloon Experiment contains a segmented calorimeter composed of 320 individual BGO crystals (18 radiation lengths deep) to determine the particle energy. Like all inorganic scintillation crystals the light output of BGO depends not only on the energy deposited by particles but also on the temperature of the crystal. ATIC had successful flights in 2000/2001 and 2002/2003 from McMurdo, Antarctica. The temperature of balloon instruments varies during their flights at altitude due to sun angle variations and differences in albedo from the ground and is monitored and recorded. In order to determine the temperature sensitivity of the ATIC calorimeter it was temperature cycled in the thermal vacuum chamber at the CSBF in Palestine, TX. The temperature dependence is derived from the pulse height response to cosmic ray muons at various temperatures.

  6. Central Calorimeter Thermal Gradient Module Connection Analysis

    SciTech Connect

    Rudland, D.L.; /Fermilab

    1987-08-07

    Two 20 kW condensing and one 10 kW steady state cooling coils will be used to cool and condense gaseous argon in the Central Calorimeter (CC) Cryostat. Since this cool down (300K to 90K) will inevitably cause shrinkage in the modules contained inside the cryostat, the connections between the modules have to be designed to withstand the increase in forces and moments induced by this contraction. This paper presents finite element analysis (ANSYS{reg_sign}) results to aid in the design or modification of the Central Calorimeter module connections.

  7. Precision Crystal Calorimeters in High Energy Physics

    ScienceCinema

    Ren-Yuan Zhu

    2016-07-12

    Precision crystal calorimeters traditionally play an important role in high energy physics experiments. In the last two decades, it faces a challenge to maintain its precision in a hostile radiation environment. This paper reviews the performance of crystal calorimeters constructed for high energy physics experiments and the progress achieved in understanding crystal’s radiation damage as well as in developing high quality scintillating crystals for particle physics. Potential applications of new generation scintillating crystals of high density and high light yield, such as LSO and LYSO, in particle physics experiments is also discussed.

  8. Photodetectors for the CMS hadron calorimeters

    NASA Astrophysics Data System (ADS)

    Elias, J. E.; CMS Hadron Calorimeter Readout Group

    1997-02-01

    Hadronic energy measurements in the central and end cap regions of the Compact Muon Solenoid (CMS) detector will be made using sampling calorimeter techniques with plastic scintillator tiles as the sensitive layers. Plastic fibers doped with wavelength shifting fluors embedded in each tile are used to extract the scintillation light. Clear plastic wave guide fibers carry the shifted light to photodetectors located on the outer surface of the calorimeter structure. Environmental constraints and physics performance requirements for these photodetectors are presented. Candidate photodetector technologies are discussed, and the hybrid photomultiplier tube technology is identified as most promising.

  9. Targeting the neurophysiology of cognitive systems with transcranial alternating current stimulation (tACS)

    PubMed Central

    Fröhlich, Flavio; Sellers, Kristin K.; Cordle, Asa L.

    2015-01-01

    Cognitive impairment represents one of the most debilitating and most difficult symptom to treat of many psychiatric illnesses. Human neurophysiology studies have suggested specific pathologies of cortical network activity correlate with cognitive impairment. However, we lack (1) demonstration of causal relationships between specific network activity patterns and cognitive capabilities and (2) treatment modalities that directly target impaired network dynamics of cognition. Transcranial alternating current stimulation (tACS), a novel non-invasive brain stimulation approach, may provide a crucial tool to tackle these challenges. We here propose that tACS can be used to elucidate the causal role of cortical synchronization in cognition and, eventually, to enhance pathologically weakened synchrony that may underlie cognitive deficits. To accelerate such development of tACS as a treatment for cognitive deficits, we discuss studies on tACS and cognition (all performed in healthy participants) according to the Research Domain Criteria (RDoC) of the National Institute of Mental Health. PMID:25547149

  10. Commissioning of the ATLAS Liquid Argon Calorimeters

    SciTech Connect

    Cooke, Mark S.

    2009-12-17

    A selection of ATLAS liquid argon (LAr) calorimeter commissioning studies is presented. It includes a coherent noise study, a measurement of the quality of the ionization pulse shape prediction, and energy and time reconstruction analyses with cosmic and single beam signals.

  11. Steel specification for the Atlas calorimeter

    SciTech Connect

    Guarino, V.

    1998-02-10

    As part of a collaborative experimental High Energy Physics experiment at the LHC Facility, CERN Laboratory, Geneva Switzerland, a group of US institutions has accepted the responsibility for constructing a large portion of the calorimeter for this experiment. This device is referred to as the Tile Calorimeter. The Tile Calorimeter has three major elements, a large center section (Barrel), and two end sections (Extended Barrel). The US group will be responsible for the construction of one of these extended barrel sections. All of the components that are required to construct this device will be fabricated in the US over a period of three years commencing in 1998. Another similar element and the barrel element will be constructed in both eastern and western Europe by parallel groups. The extended barrel is a cylindrical device approximately 8.5 meters (28 ft.) OD x 4.5 meters (14 ft.) ID, made up of 64 wedges. Each of these wedges (see Attachment 1) is constructed by bolting submodules to a strongback girder. Each submodule is constructed of a series of sheets that are welded and glued together. This document summarizes the characteristics and specifications of these steel sheets. The Tile Calorimeter is the return path for the magnet flux of the ATLAS internal superconducting 2T solenoid, therefore its steel magnetic properties are important.

  12. SLD liquid argon calorimeter prototype test results

    SciTech Connect

    Dubois, R.; Eigen, G.; Au, Y.; Sleeman, J.; Breidenbach, M.; Brau, J.; Ludgate, G.A.; Oram, C.J.; Cook, V.; Johnson, J.

    1985-10-01

    The results of the SLD test beam program for the selection of a calorimeter radiator composition within a liquid argon system are described, with emphasis on the study of the use of uranium to obtain equalization of pion and electron responses.

  13. Performance of the GEM electromagnetic calorimeter

    SciTech Connect

    Hong Ma

    1993-06-25

    The GEM EM calorimeter is optimized for the best energy, position, angular resolution and jet rejection. The detailed simulation results are presented. In the barrel with LKr, an energy resolution of about 6%/{radical}{direct_sum}0.4%, pointing resolution of 40mrad/{radical}E + 0.5mrad, and jet rejection of a factor of 5 are expected.

  14. Transcranial Alternating Current Stimulation (tACS) Enhances Mental Rotation Performance during and after Stimulation

    PubMed Central

    Kasten, Florian H.; Herrmann, Christoph S.

    2017-01-01

    Transcranial alternating current stimulation (tACS) has been repeatedly demonstrated to modulate endogenous brain oscillations in a frequency specific manner. Thus, it is a promising tool to uncover causal relationships between brain oscillations and behavior or perception. While tACS has been shown to elicit a physiological aftereffect for up to 70 min, it remains unclear whether the effect can still be elicited if subjects perform a complex task interacting with the stimulated frequency band. In addition, it has not yet been investigated whether the aftereffect is behaviorally relevant. In the current experiment, participants performed a Shepard-like mental rotation task for 80 min. After 10 min of baseline measurement, participants received either 20 min of tACS at their individual alpha frequency (IAF) or sham stimulation (30 s tACS in the beginning of the stimulation period). Afterwards another 50 min of post-stimulation EEG were recorded. Task performance and EEG were acquired during the whole experiment. While there were no effects of tACS on reaction times or event-related-potentials (ERPs), results revealed an increase in mental rotation performance in the stimulation group as compared to sham both during and after stimulation. This was accompanied by increased ongoing alpha power and coherence as well as event-related-desynchronization (ERD) in the alpha band in the stimulation group. The current study demonstrates a behavioral and physiological aftereffect of tACS in parallel. This indicates that it is possible to elicit aftereffects of tACS during tasks interacting with the alpha band. Therefore, the tACS aftereffect is suitable to achieve an experimental manipulation. PMID:28197084

  15. Optimization of the Air Apportionment in a Tac Thunder Scenario Using Response Surface Methodology

    DTIC Science & Technology

    1994-03-01

    AD-A278 494 L" t22$ OPTIMIZATION OF THE AIR APPORTIONMENT IN A TAC THUNDER SCENARIO USING RESPONSE SURFACE METHODOLOGY THESIS Steven Lee Forsythe...Availability Codes Avail and /or Dist Special OPTIMIZATION OF THE AIR APPORTIONMENT IN A TAC THUNDER SCENARIO USING RESPONSE SURFACE METHODOLOGY ...Using Response Surface Methodology DEFENSE DATE: 01 March 94 COMMITTEE: NAME/DEPARTMENT SIGNATURE Advisor: Lt Col Paul F. Auclair 6.d .4 Assistant

  16. Final report of the UMTRA independent technical review of TAC audit programs

    SciTech Connect

    Not Available

    1994-10-01

    This report details the findings of an Independent Technical Review (ITR) of practices and procedures for the Uranium Mill Tailings Remedial Action (UMTRA) Project audit program. The audit program is conducted by Jacobs Engineering Group Inc., the Technical Assistance Contractor (TAC) for the UMTRA Project. The purpose of the ITR was to ensure that the TAC audit program is effective and is conducted efficiently. The ITR was conducted from May 16-20, 1994. A review team observed audit practices in the field, reviewed the TAC audit program`s documentation, and discussed the program with TAC staff and management. The format of this report has been developed around EPA guidelines; they comprise most of the major section headings. Each section begins by identifying the criteria that the TAC program is measured against, then describing the approach used by the ITR team to measure each TAC audit program against the criteria. An assessment of each type of audit is then summarized for each component in the following order: Radiological audit summary; Health and safety audit summary; Environmental audit summary; Quality assurance audit summary.

  17. Evaluation of the Virginia Training and Technical Assistance Center (T/TAC) System. T/TAC Cross Case Report, December 1999. Executive Summary.

    ERIC Educational Resources Information Center

    Zantal-Wiener, Kathy; Rous, Beth; Lutzer, Christie; Mushegan, Tiffany; Waddell, Christina

    This document presents results of an evaluation of Virginia's Department of Education's Training and Technical Assistance Centers (T/TACs), a statewide system of technical assistance which emphasizes collaboration in the planning and provision of services to children and youth with disabilities or at risk for school failure. Evaluation results are…

  18. X-Ray Calorimeter Arrays for Astrophysics

    NASA Technical Reports Server (NTRS)

    Kilbourne, Caroline A.

    2009-01-01

    High-resolution x-ray spectroscopy is a powerful tool for studying the evolving universe. The grating spectrometers on the XMM and Chandra satellites started a new era in x-ray astronomy, but there remains a need for instrumentation that can provide higher spectral resolution with high throughput in the Fe-K band (around 6 keV) and can enable imaging spectroscopy of extended sources, such as supernova remnants and galaxy clusters. The instrumentation needed is a broad-band imaging spectrometer - basically an x-ray camera that can distinguish tens of thousands of x-ray colors. The potential benefits to astrophysics of using a low-temperature calorimeter to determine the energy of an incident x-ray photon via measurement of a small change in temperature was first articulated by S. H. Moseley over two decades ago. In the time since, technological progress has been steady, though full realization in an orbiting x-ray telescope is still awaited. A low-temperature calorimeter can be characterized by the type of thermometer it uses, and three types presently dominate the field. The first two types are temperature-sensitive resistors - semiconductors in the metal-insulator transition and superconductors operated in the superconducting-normal transition. The third type uses a paramagnetic thermometer. These types can be considered the three generations of x-ray calorimeters; by now each has demonstrated a resolving power of 2000 at 6 keV, but only a semiconductor calorimeter system has been developed to spaceflight readiness. The Soft X-ray Spectrometer on Astro-H, expected to launch in 2013, will use an array of silicon thermistors with I-IgTe x-ray absorbers that will operate at 50 mK. Both the semiconductor and superconductor calorimeters have been implemented in small arrays, kilo-pixel arrays of the superconducting calorimeters are just now being produced, and it is anticipated that much larger arrays will require the non-dissipative advantage of magnetic thermometers.

  19. I-TAC/CXCL11 is a natural antagonist for CCR5.

    PubMed

    Petkovic, Vibor; Moghini, Christian; Paoletti, Samantha; Uguccioni, Mariagrazia; Gerber, Basil

    2004-09-01

    The selective CXC chemokine receptor 3 (CXCR3) agonists, monokine induced by interferon-gamma (IFN- gamma)/CXC chemokine ligand 9 (CXCL9), IFN-inducible protein 10/CXCL10, and IFN-inducible T cell alpha chemoattractant (I-TAC)/CXCL11, attract CXCR3+ cells such as CD45RO+ T lymphocytes, B cells, and natural killer cells. Further, all three chemokines are potent, natural antagonists for chemokine receptor 3 (CCR3) and feature defensin-like, antimicrobial activities. In this study, we show that I-TAC, in addition to these effects, acts as an antagonist for CCR5. I-TAC inhibited the binding of macrophage-inflammatory protein-1alpha (MIP-1alpha)/CC chemokine ligand 3 (CCL3) to cells transfected with CCR5 and to monocytes. Furthermore, cell migration evoked by regulated on activation, normal T expressed and secreted (RANTES)/CCL5 and MIP-1beta/CCL4, the selective agonist of CCR5, was inhibited in transfected cells and monocytes, respectively. In two other functional assays, namely the release of free intracellular calcium and actin polymerization, I-TAC reduced CCR5 activities to minimal levels. Sequence and structure analyses indicate a potential role for K17, K49, and Q51 of I-TAC in CCR5 binding. Our results expand on the potential role of I-TAC as a negative modulator in leukocyte migration and activation, as I-TAC would specifically counteract the responses mediated by many "classical," inflammatory chemokines that act not only via CCR3 but via CCR5 as well.

  20. Effect of dead material in a calorimeter

    SciTech Connect

    Green, D.

    1995-10-01

    The existence of dead material in any practical calorimeter system is simply a fact of life. The task for the designer, then, is to understand the impact on the Physics in question, and strive to minimize it. The aim of this note is to use the ``Hanging File`` test data, which has fined grained individual readout of about 100 depth segments, to explore impact of dead material on the mean and r.m.s. of the hadronic distribution. The amount and location of the dead material is varied. It important to remember that the Hanging File data was calibrated, EM to HCAL compartment, so as to minimize the electron to pion energy dependence. In practical terms e/pie was made = 1.0 at an incident energy of about 100 GeV. Note that the PB(EM) + FE(HCAL) calorimeter was not a compensating device.

  1. Level-2 Calorimeter Trigger Upgrade at CDF

    SciTech Connect

    Flanagan, G.U.; /Purdue U.

    2007-04-01

    The CDF Run II Level-2 calorimeter trigger is implemented in hardware and is based on an algorithm used in Run I. This system insured good performance at low luminosity obtained during the Tevatron Run II. However, as the Tevatron instantaneous luminosity increases, the limitations of the current system due to the algorithm start to become clear. In this paper, we will present an upgrade of the Level-2 calorimeter trigger system at CDF. The upgrade is based on the Pulsar board, a general purpose VME board developed at CDF and used for upgrading both the Level-2 tracking and the Level-2 global decision crate. This paper will describe the design, hardware and software implementation, as well as the advantages of this approach over the existing system.

  2. Improving calorimeter resolution using temperature compensation calculations

    NASA Astrophysics Data System (ADS)

    Smiga, Joseph; Purschke, Martin

    2017-01-01

    The sPHENIX experiment is an upgrade of the existing PHENIX apparatus at the Relativistic Heavy-Ion Collider (RHIC). The new detector improves upon measurements of various physical processes, such as jets of particles created during heavy-ion collisions. Prototypes of various calorimeter components were tested at the Fermilab Test Beam Facility (FTBF). This analysis tries to compensate the effects of temperature drifts in the silicon photomultipliers (SiPMs). Temperature data were used to calculate an appropriate compensation factor. This analysis will improve the achievable resolution and will also determine how accurately the temperature must be controlled in the final experiment. This will improve the performance of the calorimeters in the sPHENIX experiment. This project was supported in part by the U.S. Department of Energy, Office of Science, Office of Workforce Development for Teachers and Scientists (WDTS) under the Science Undergraduate Laboratory Internships Program (SULI).

  3. Sources of compensation in hadronic calorimeters

    SciTech Connect

    Goodman, M.S.; Gabriel, T.A.; Di Ciaccio, A.; Wilson, R.

    1988-12-01

    Monte Carlo simulations are presented using the CALOR code system to study the design of a large hybrid hadron calorimeter system employing a warm liquid active medium (tetramethylsilane, Si(CH/sub 3/)/sub 4/) and uranium plates in addition to a conventional Fe/plastic system. In the system described here, the uranium provides partial compensation by suppressing the electromagnetic cascade produced by incident electrons due to sampling inefficiencies. The results of the simulations also indicate that significant compensation is achieved (given small enough saturation) due to low energy recoil protons produced in collisions with low energy (1--20 MeV) cascade and fission neutrons in the active medium. Both compensation mechanisms are important to help balance the response of a calorimeter to incident electrons and hadrons, that is, to achieve a ratio of pulse heights (e/h approx. 1) which will lead to the best energy resolution. 17 refs., 4 figs., 2 tabs.

  4. Upgrade of the ATLAS Tile Calorimeter Electronics

    NASA Astrophysics Data System (ADS)

    Carrió, F.; Tile Calorimeter System, ATLAS

    2015-02-01

    The Tile Calorimeter (TileCal) is the hadronic calorimeter covering the central region of the ATLAS experiment at LHC. The TileCal readout consists of about 10000 channels. The bulk of its upgrade will occur for the High Luminosity LHC phase (Phase-II) where the peak luminosity will increase 5 times compared to the design luminosity (1034 cm-2s-1) but with maintained energy (i.e. 7+7 TeV). An additional increase of the average luminosity with a factor of 2 can be achieved by luminosity levelling. This upgrade is expected to happen around 2024. The TileCal upgrade aims at replacing the majority of the on- and off- detector electronics to the extent that all calorimeter signals will be digitized and sent to the off-detector electronics in the counting room. To achieve the required reliability, redundancy has been introduced at different levels. Three different options are presently being investigated for the front-end electronic upgrade. Extensive test beam studies will determine which option will be selected. 10 Gbps optical links are used to read out all digitized data to the counting room while 5 Gbps down-links are used for synchronization, configuration and detector control. For the off-detector electronics a pre-processor (sROD) is being developed, which takes care of the initial trigger processing while temporarily storing the main data flow in pipeline and derandomizer memories. One demonstrator prototype module with the new calorimeter module electronics, but still compatible with the present system, is planned to be inserted in ATLAS this year.

  5. A no-load RF calorimeter

    NASA Technical Reports Server (NTRS)

    Chernoff, R. C.

    1975-01-01

    The described device can be used to measure the output of any dc powered RF source. No dummy load is required for the measurements. The device is, therefore, called the 'no-load calorimeter' (NLC). The NLC measures the power actually fed to the antenna or another useful load. It is believed that the NLC can compete successfully with directional coupler type systems in measuring the output of high-power RF sources.

  6. Precision timing calorimeter for high energy physics

    NASA Astrophysics Data System (ADS)

    Anderson, Dustin; Apresyan, Artur; Bornheim, Adolf; Duarte, Javier; Peña, Cristián; Spiropulu, Maria; Trevor, Jason; Xie, Si; Ronzhin, Anatoly

    2016-07-01

    Scintillator based calorimeter technology is studied with the aim to achieve particle detection with a time resolution on the order of a few 10 ps for photons and electrons at energies of a few GeV and above. We present results from a prototype of a 1.4×1.4×11.4 cm3 sampling calorimeter cell consisting of tungsten absorber plates and Cerium-doped Lutetium Yttrium Orthosilicate (LYSO) crystal scintillator plates. The LYSO plates are read out with wave lengths shifting fibers which are optically coupled to fast photo detectors on both ends of the fibers. The measurements with electrons were performed at the Fermilab Test Beam Facility (FTBF) and the CERN SPS H2 test beam. In addition to the baseline setup plastic scintillation counter and a MCP-PMT were used as trigger and as a reference for a time of flight measurement (TOF). We also present measurements with a fast laser to further characterize the response of the prototype and the photo sensors. All data were recorded using a DRS4 fast sampling digitizer. These measurements are part of an R&D program whose aim is to demonstrate the feasibility of building a large scale electromagnetic calorimeter with a time resolution on the order of 10 ps, to be used in high energy physics experiments.

  7. Preliminary conceptual design about the CEPC calorimeters

    NASA Astrophysics Data System (ADS)

    Yang, Haijun

    2016-11-01

    The Circular Electron Positron Collider (CEPC) as a Higgs factory was proposed in September 2013. The preliminary conceptual design report was completed in 2015.1 The CEPC detector design was using International Linear Collider Detector — ILD2 as an initial baseline. The CEPC calorimeters, including the high granularity electromagnetic calorimeter (ECAL) and the hadron calorimeter (HCAL), are designed for precise energy measurements of electrons, photons, taus and hadronic jets. The basic resolution requirements for the ECAL and HCAL are about 16%E (GeV) and 50%E (GeV), respectively. To fully exploit the physics potential of the Higgs, W, Z and related Standard Model processes, the jet energy resolution is required to reach 3%-4%, or 30%/E (GeV) at energies below about 100 GeV. To achieve the required performance, a Particle Flow Algorithm (PFA) — oriented calorimetry system is being considered as the baseline design. The CEPC ECAL detector options include silicon-tungsten or scintillator-tungsten structures with analog readout, while the HCAL detector options have scintillator or gaseous detector as the active sensor and iron as the absorber. Some latest R&D studies about ECAL and HCAL within the CEPC working group is also presented.

  8. Fiber and crystals dual readout calorimeters

    NASA Astrophysics Data System (ADS)

    Cascella, Michele; Franchino, Silvia; Lee, Sehwook

    2016-11-01

    The RD52 (DREAM) collaboration is performing R&D on dual readout calorimetry techniques with the aim of improving hadronic energy resolution for future high energy physics experiments. The simultaneous detection of Cherenkov and scintillation light enables us to measure the electromagnetic fraction of hadron shower event-by-event. As a result, we could eliminate the main fluctuation which prevented from achieving precision energy measurement for hadrons. We have tested the performance of the lead and copper fiber prototypes calorimeters with various energies of electromagnetic particles and hadrons. During the beam test, we investigated the energy resolutions for electrons and pions as well as the identification of those particles in a longitudinally unsegmented calorimeter. Measurements were also performed on pure and doped PbWO4 crystals, as well as BGO and BSO, with the aim of realizing a crystal based dual readout detector. We will describe our results, focusing on the more promising properties of homogeneous media for the technique. Guidelines for additional developments on crystals will be also given. Finally we discuss the construction techniques that we have used to assemble our prototypes and give an overview of the ones that could be industrialized for the construction of a full hermetic calorimeter.

  9. The Zeus calorimeter first level trigger

    SciTech Connect

    Smith, W.J.

    1989-04-01

    The design of the Zeus Detector Calorimeter Level Trigger is presented. The Zeus detector is being built for operation at HERA, a new storage ring that will provide collisions between 820 GeV protons and 30 GeV electrons in 1990. The calorimeter is made of depleted uranium plates and plastic scintillator read out by wavelength shifter bars into 12,864 photomultiplier tubes. These signals are combined into 974 trigger towers with separate electromagnetic and hadronic sums. The calorimeter first level trigger is pipelined with a decision provided 5 {mu}sec after each beam crossing, occurring every 96 nsec. The trigger determines the total energy, the total transverse energy, the missing energy, and the energy and number of isolated electrons and muons. It also provides information on the number and energy of clusters. The trigger rate needs to be held to 1 kHz against a rate of proton-beam gas interactions of approximately 500 kHz. The summed trigger tower pulseheights are digitized by flash ADC`s. The digital values are linearized, stored and used for sums and pattern tests.

  10. Calibrating the Muon Piston Calorimeter (MPC)

    NASA Astrophysics Data System (ADS)

    Skolnik, Marianne

    2012-10-01

    The Muon Piston Calorimeter (MPC) is a subsystem of the PHENIX detector. The MPC, an electromagnetic calorimeter, is effective at measuring the energy of photons and electrons produced from collisions at the Relativistic Heavy Ion Collider (RHIC). The MPC outputs a voltage signal that we then convert into an energy reading. One common way to calibrate electromagnetic calorimeters is to use photons from π^0 decays. Since many of the photons that enter the detector are the result of natural pion decay, we can pair up the photons and create π^0 candidates. We then plot their masses tower by tower and with the correct cuts a mass peak will appear close to the position predicted by the simulation PISA of the PHENIX detector. Then, we relate the mass peaks from the measured data to mass peaks from simulated data to adjust the gains. Once the MPC is calibrated we can use it to study Au+Au collisions. Previously, the detector has been used to study spin physics using data collected from p+p collisions, and cold nuclear matter effects using d+Au collisions. These new calibrations will allow us to measure new global variables such as transverse energy in both the forward and backward kinematic regions, 3.1< |η| < 3.9.

  11. A 6-Point TACS Score Predicts In-Hospital Mortality Following Total Anterior Circulation Stroke

    PubMed Central

    Wood, Adrian D; Gollop, Nicholas D; Bettencourt-Silva, Joao H; Clark, Allan B; Metcalf, Anthony K; Bowles, Kristian M; Flather, Marcus D; Potter, John F

    2016-01-01

    Background and Purpose Little is known about the factors associated with in-hospital mortality following total anterior circulation stroke (TACS). We examined the characteristics and comorbidity data for TACS patients in relation to in-hospital mortality with the aim of developing a simple clinical rule for predicting the acute mortality outcome in TACS. Methods A routine data registry of one regional hospital in the UK was analyzed. The subjects were 2,971 stroke patients with TACS (82% ischemic; median age=81 years, interquartile age range=74–86 years) admitted between 1996 and 2012. Uni- and multivariate regression models were used to estimate in-hospital mortality odds ratios for the study covariates. A 6-point TACS scoring system was developed from regression analyses to predict in-hospital mortality as the outcome. Results Factors associated with in-hospital mortality of TACS were male sex [adjusted odds ratio (AOR)=1.19], age (AOR=4.96 for ≥85 years vs. <65 years), hemorrhagic subtype (AOR=1.70), nonlateralization (AOR=1.75), prestroke disability (AOR=1.73 for moderate disability vs. no symptoms), and congestive heart failure (CHF) (AOR=1.61). Risk stratification using the 6-point TACS Score [T=type (hemorrhage=1 point) and territory (nonlateralization=1 point), A=age (65–84 years=1 point, ≥85 years=2 points), C=CHF (if present=1 point), S=status before stroke (prestroke modified Rankin Scale score of 4 or 5=1 point)] reliably predicted a mortality outcome: score=0, 29.4% mortality; score=1, 46.2% mortality [negative predictive value (NPV)=70.6%, positive predictive value (PPV)=46.2%]; score=2, 64.1% mortality (NPV=70.6, PPV=64.1%); score=3, 73.7% mortality (NPV=70.6%, PPV=73.7%); and score=4 or 5, 81.2% mortality (NPV=70.6%, PPV=81.2%). Conclusions We have identified the key determinants of in-hospital mortality following TACS and derived a 6-point TACS Score that can be used to predict the prognosis of particular patients. PMID:27819414

  12. A hadron calorimeter with scintillators parallel to the beam

    NASA Astrophysics Data System (ADS)

    Abramov, V.; Goncharov, P.; Gorin, A.; Gurzhiev, A.; Dyshkant, A.; Evdokimov, V.; Kolosov, V.; Korablev, A.; Korneev, Yu.; Kostritskii, A.; Krinitsyn, A.; Kryshkin, V.; Podstavkov, V.; Polyakov, V.; Shtannikov, A.; Tereschenko, S.; Turchanovich, L.; Zaichenko, A.

    1997-02-01

    A hadron calorimeter in which scintillators are arranged nearly parallel to the incident particle direction and light is collected by optical fibres with WLS, has been built. The iron absorber plates are of the tapered shape to fit a barrel structure of the collider geometry. The performance of the calorimeter studied with hadron beam is presented as a function of tilt angle without and with electromagnetic calorimeter in front of the hadron one.

  13. Heat flow calorimeter. [measures output of Ni-Cd batteries

    NASA Technical Reports Server (NTRS)

    Fletcher, J. C.; Johnston, W. V. (Inventor)

    1974-01-01

    Heat flow calorimeter devices are used to measure heat liberated from or absorbed by an object. This device is capable of measuring the thermal output of sealed nickel-cadmium batteries or cells during charge-discharge cycles. An elongated metal heat conducting rod is coupled between the calorimeter vessel and a heat sink, thus providing the only heat exchange path from the calorimeter vessel itself.

  14. Test beam performance of the CDF plug upgrade hadron calorimeter

    SciTech Connect

    de Barbaro, P.; CDF Plug Upgrade Group

    1998-01-13

    We report on the performance of the CDF End Plug Hadron Calorimeter in a test beam. The sampling calorimeter is constructed using 2 inch iron absorber plates and scintillator planes with wavelength shifting fibers for readout. The linearity and energy resolution of the calorimeter response to pions, and the transverse uniformity of the response to muons and pions are presented. The parameter e/h, representing the ratio of the electromagnetic to hadronic response, is extracted from the data.

  15. Performance of CDF calorimeter simulation for Tevatron Run II

    SciTech Connect

    C. Currat

    2002-09-19

    The upgraded CDF II detector has collected first data during the initial operation of the Tevatron accelerator in Run II. The simulation of the CDF electromagnetic and hadronic central and upgraded plug (forward) calorimeter is based on the Gflash calorimeter parameterization package used within the GEANT based detector simulation of the Run II CDF detector. We present the results of tuning the central and plug calorimeter response to test beam data.

  16. A calorimeter for neutron flux measurement. Final report

    SciTech Connect

    Chupp, T.E.

    1993-04-01

    A calorimeter for absolute neutron flux measurement has been built and tested. The calorimeter measures the heat produced in a 10{degrees}K thick LiPb target when neutrons are captured via the {sup 6}Li(n,{sup 3}H){sup 4}He reaction. The sensitivity achieved was 1.3x10{sup 6} n/s for a 1 hour measurement. Separate flux measurements with the calorimeter and a {sup 238}U fission chamber are in agreement and show that systematic errors are less than 3%. An improved calorimeter has been built which is sensitive to 10{sup 5} n/s for a 1 hour measurement.

  17. sPHENIX Calorimeter Design and Jet Performance

    NASA Astrophysics Data System (ADS)

    Haggerty, John S.

    2016-12-01

    The PHENIX collaboration is planning a detector upgrade, sPHENIX, which consists of large acceptance calorimetry and tracking detectors built around the superconducting solenoid recently shipped to Brookhaven from the decommissioned BaBar experiment at SLAC. The sPHENIX calorimeter system includes three radial layers of sampling calorimeters, a tungsten-scintillating fiber electromagnetic calorimeter, and two longitudinally segmented sampling hadron calorimeters that are made of scintillator tiles and steel plates. Together, they provide hermetic coverage in | η | < 1 for calorimetry based jet measurements as well as minimal bias jet trigger capability, which coupled with high resolution tracking, enable an extremely rich jet physics program at RHIC.

  18. Probing electronic states of TaC and observation of a stable excited state of TaC- by anion-photoelectron spectroscopy

    NASA Astrophysics Data System (ADS)

    Aravind, G.; Nrisimhamurty, M.; Mane, Rupali G.; Gupta, A. K.; Krishnakumar, E.

    2015-10-01

    We report the experimental value of electron affinity for TaC to be 1.928(0.056) eV by performing photodetachment of its anion at 355 nm. An excited-electronic state of the anion, stable against autodetachment, is observed lying 0.828 eV above the ground-electronic state. Five low-lying electronic states of TaC are observed and identified by comparison with restricted second-order configuration interaction (SOCI) calculations. Vibrational frequencies for the electronic states are obtained from the analysis of the measured data. We also present the results of density functional theory (DFT) calculations performed on the adiabatic electron affinity, yielding a value of 1.9236 eV and vertical detachment energy value of 1.924 eV.

  19. Preparation and in vivo evaluation of linkers for 211At labeling of humanized anti-Tac.

    PubMed

    Yordanov, A T; Garmestani, K; Zhang, M; Zhang, Z; Yao, Z; Phillips, K E; Herring, B; Horak, E; Beitzel, M P; Schwarz, U P; Gansow, O A; Plascjak, P S; Eckelman, W C; Waldmann, T A; Brechbiel, M W

    2001-10-01

    The syntheses, radiolabeling, antibody conjugation, and in vivo evaluation of new linkers for 211At labeling of humanized anti-Tac (Hu-anti-Tac), an antibody to the alpha-chain of the IL-2 receptor (IL-2Ralpha) shown to be a useful target for radioimmunotherapy are described. Synthesis of the organometallic linker precursors is accomplished by reaction of the corresponding bromo- or iodoaryl esters with bis(tributyltin) in the presence of a palladium catalyst. Subsequent conversion to the corresponding N-succinimidyl ester and labeling with 211At of two new linkers, N-succinimidyl 4-[211At]astato-3-methylbenzoate and N-succinimidyl N-(4-[211At]astatophenethyl)succinamate (SAPS), together with the previously reported N-succinimidyl 4-[211At]astatobenzoate and N-succinimidyl 3-[211At]astato-4-methylbenzoate, are each conjugated to Hu-anti-Tac. The plasma survival times of these conjugates are compared to those of directly iodinated (125I) Hu-anti-Tac. The N-succinimidyl N-(4-[211At]astatophenethyl)succinamate compound (SAPS) emerged from this assay as the most viable candidate for 211At-labeling of Hu-anti-Tac. SAPS, along with the directly analogous radio-iodinated reagent, N-succinimidyl N-(4-[125I]astatophenethyl)succinamate (SIPS), are evaluated in a biodistribution study along with directly iodinated (125I) Hu-anti-Tac. Blood clearance and biological accretion results indicate that SAPS is a viable candidate for further evaluation for radioimmunotherapy of cancer.

  20. Dynamic Consolidation of TaC and Nano-YSZ Powders (POSTPRINT)

    DTIC Science & Technology

    2006-01-01

    more fracture resistant TaC. TaC powders of size less than 3μm, and grain size ranging from 0.5 to 1μm, were packed in double-tube steel vessels and...ranging from 0.5 to 1μm, were packed in double-tube steel vessels and subjected to explosive consolidation. The double-tube configuration was selected...temperature ( DBTT ) of 1750 - 2000°C [3], allowing it to be shaped above DBTT . However, one drawback in processing is that conventional techniques such as

  1. Dynamic Consolidation of TaC and Nano-YSZ Powders (PREPRINT)

    DTIC Science & Technology

    2006-02-07

    fracture resistant TaC. TaC powders of size less than 3μm, and grain size ranging from 0.5 to 1μm, were packed in double-tube steel vessels and subjected...TaC powders of size less than 3μm, and grain size ranging from 0.5 to 1μm, were packed in double-tube steel vessels and subjected to explosive...material also has a ductile to brittle transition temperature ( DBTT ) of 1750 - 2000°C [3], allowing it to be shaped above DBTT . However, one drawback

  2. ZYG-9, TAC-1 and ZYG-8 together ensure correct microtubule function throughout the cell cycle of C. elegans embryos.

    PubMed

    Bellanger, Jean-Michel; Carter, J Clayton; Phillips, Jennifer B; Canard, Coralie; Bowerman, Bruce; Gönczy, Pierre

    2007-08-15

    The early Caenorhabditis elegans embryo is well suited for investigating microtubule-dependent cell division processes. In the one-cell stage, the XMAP215 homologue ZYG-9, associated with the TACC protein TAC-1, promotes microtubule growth during interphase and mitosis, whereas the doublecortin domain protein ZYG-8 is required for anaphase spindle positioning. How ZYG-9, TAC-1 and ZYG-8 together ensure correct microtubule-dependent processes throughout the cell cycle is not fully understood. Here, we identify new temperature-sensitive alleles of zyg-9 and tac-1. Analysis of ZYG-9 and TAC-1 distribution in these mutants identifies amino acids important for centrosomal targeting and for stability of the two proteins. This analysis also reveals that TAC-1 is needed for correct ZYG-9 centrosomal enrichment. Moreover, we find that ZYG-9, but not TAC-1, is limiting for microtubule-dependent processes in one-cell-stage embryos. Using two of these alleles to rapidly inactivate ZYG-9-TAC-1 function, we establish that this complex is required for correct anaphase spindle positioning. Furthermore, we uncover that ZYG-9-TAC-1 and ZYG-8 function together during meiosis, interphase and mitosis. We also find that TAC-1 physically interacts with ZYG-8 through its doublecortin domain, and that in vivo TAC-1 and ZYG-8 are part of a complex that does not contain ZYG-9. Taken together, these findings indicate that ZYG-9-TAC-1 and ZYG-8 act in a partially redundant manner to ensure correct microtubule assembly throughout the cell cycle of early C. elegans embryos.

  3. Do leaf total antioxidant capacities (TAC) reflect specific antioxidant potentials? - A comparison of TAC and reactive oxygen scavenging in tobacco leaf extracts.

    PubMed

    Majer, Petra; Stoyanova, Silviya; Hideg, Eva

    2010-07-02

    Two traditional methods of total antioxidant capacity (TAC) assessment, Trolox equivalent antioxidant capacity (TEAC) and ferric reducing antioxidant power (FRAP) were applied to water extracts from tobacco leaves at various stages of senescence. Physiological status of the leaves was characterized by the effective photochemical quantum yield of photosynthesis (Y(II)). TAC values were compared to amounts of total phenolics, carotenoid contents and also to reactive oxygen scavenging capacities of the leaf extracts. To this end a new, simple fluorimetric assay was introduced for testing hydroxyl radical neutralizing capacity in leaf extracts. We found that while both TAC values increased with declining photosynthesis and decreasing pigment content, they were not characteristic to specific superoxide or hydroxyl radical scavenging and had limited connection to leaf antioxidant content. Good linear correlations were only found between the following pairs of parameters: Y(II) - total carotenoid, TEAC - total carotenoid, FRAP - total phenolics. Our data show that TEAC and FRAP are not interchangeable in leaf studies and do not represent antioxidant action on ROS.

  4. T-1018 UCLA Spacordion Tungsten Powder Calorimeter

    SciTech Connect

    Trentalange, Stephen; Tsai, Oleg; Igo, George; Huang, Huan; Pan, Yu Xi; Dunkelberger, Jay; Xu, Wen Qin; Soha, Aria; Heppelmann, Steven; Gagliardi, Carl; /Texas A-M

    2011-11-16

    The present experiments at the BNL-RHIC facility are evolving towards physics goals which require the detection of medium energy electromagnetic particles (photons, electrons, neutral pions, eta mesons, etc.), especially at forward angles. New detectors will place increasing demands on energy resolution, hadron rejection and two-photon resolution and will require large area, high performance electromagnetic calorimeters in a variety of geometries. In the immediate future, either RHIC or JLAB will propose a facility upgrade (Electron-Ion Collider, or EIC) with physics goals such as electron-heavy ion collisions (or p-A collisions) with a wide range of calorimeter requirements. An R and D program based at Brookhaven National Laboratory has awarded the group funding of approximately $110,000 to develop new types of calorimeters for EIC experiments. The UCLA group is developing a method to manufacture very flexible and cost-effective, yet high quality calorimeters based on scintillating fibers and tungsten powder. The design and features of the calorimeter can be briefly stated as follows: an arbitrarily large number of small diameter fibers (< 0.5 mm) are assembled as a matrix and held rigidly in place by a set of precision screens inside an empty container. The container is then back-filled with tungsten powder, compacted on a vibrating table and infused with epoxy under vacuum. The container is then removed. The resulting sub-modules are extremely uniform and achieve roughly the density of pure Lead. The sub-modules are stacked together to achieve a final detector of the desired shape. There is no dead space between sub-modules and the fibers can be in an accordion geometry bent to prevent 'channeling' of the particles due to accidental alignment of their track with the module axis. This technology has the advantage of being modular and inexpensive to the point where the construction work may be divided among groups the size of typical university physics departments

  5. The simulation of the CMS electromagnetic calorimeter

    NASA Astrophysics Data System (ADS)

    Cossutti, F.

    2008-07-01

    The CMS Collaboration has developed a detailed simulation of the electromagnetic calorimeter (ECAL), which has been fully integrated in the collaboration software framework CMSSW. The simulation is based on the Geant4 detector simulation toolkit for the modelling of the passage of particles through matter and magnetic field. The geometrical description of the detector is being re-implemented using the DetectorDescription language, combining an XML based description with the algorithmic definition of the position of the elements. The ECAL simulation software is fully operational and has been validated using real data from the ECAL test beam experiment that took place in summer 2006.

  6. Calorimeter measurements of low wattage items

    SciTech Connect

    Cremers, T.L.; Camp, K.L.; Hildner, S.S.; Sedlacek, W.A.

    1993-08-01

    The transition of DOE facilities from production to decontamination and decommissioning has led to more measurements of waste, scrap, and other less attractive materials. The difficulty that these materials pose for segmented gamma scanning and neutron counting has increased the use of calorimetric assay for very low wattage items (< 250 millwatts). We have measured well characterized {sup 238}Pu oxide ranging in wattage from 25 to 500 milliwatts in the calorimeters at the Los Alamos Plutonium Facility and report the error and the precision of the measurements.

  7. Isothermal drop calorimeter provides measurements for alpha active, pyrophoric materials

    NASA Technical Reports Server (NTRS)

    Savage, H.

    1969-01-01

    Isothermal drop calorimeter measures the heat content of intensely alpha active and pyrophoric materials in inert atmospheres. It consists of a furnace, calorimeter, and aluminum isothermal jacket contained within an inert-atmosphere glove box, which permits the use of unencapsulated materials without exposing personnel to alpha contamination.

  8. Ac loss calorimeter for three-phase cable

    SciTech Connect

    Daney, D.E.; Boenig, H.J.; Maley, M.P.; McMurry, D.E.; DeBlanc, B.G.

    1996-10-01

    A calorimeter for measuring ac losses in meter-long lengths of HTS superconducting power transmission line cables is described. The calorimeter, which is based on a temperature difference technique, has a precision of 1 mW and measures single, two-phase (coupling), and three-phase losses. The measurements show significant coupling losses between phases.

  9. Contribution of AP-1 interference induced by TAC-101 to tumor growth suppression in a hepatocellular carcinoma model.

    PubMed

    Eshima, Kokoro; Fukaya, Satoshi; Sugimoto, Akiko; Mori, Tomoko; Yokoi, Hiromi; Yamamoto, Yasuji; Sugiura, Shin; Honda, Shizu; Masuko, Norio; Murakami, Koji; Yamasaki, Yasundo; Kagechika, Hiroyuki

    2009-01-01

    TAC-101, 4-[3,5-bis(trimethylsilyl)benzamido] benzoic acid, is a synthetic ligand for retinoic acid receptor (RAR)-alpha. Here, we demonstrate the contribution of TAC-101-induced AP-1 interference to stabilization of tumor growth. TAC-101 induced transcriptional activation of RAR, resulting in marked elevation of RARbeta, a representative retinoid response marker, and it also significantly repressed the transcriptional activity of AP-1 in JHH-7 cells. In contrast to JHH-7, JHH-6 is another RARalpha-expressing human hepatocellular carcinoma (HCC) cell line with constitutive activation of AP-1, but it is retinoid insensitive and did not respond to the TAC-101-induced RAR signal. TAC-101 did not inhibit AP-1 activity of the JHH-6 cell line, showing that AP-1 interference by TAC-101 must be in parallel with RAR activation. Interleukin-8 (IL-8), one of the AP-1-regulated factors which correlate with a poor prognosis in HCC patients, was found to be overexpressed in JHH-7 cells. TAC-101 reduced IL-8 production without cytotoxicity and inhibited the progression of HCC in the orthotopic mouse model with decreased tumor IL-8 level. These results suggest that downregulation of the extracellular biomarker for AP-1 interference via the induction of retinoid signals will enhance the pharmacological effect of TAC-101 on HCC and it could be useful as a surrogate biomarker of therapeutic efficacy.

  10. Stimulus Presentation at Specific Neuronal Oscillatory Phases Experimentally Controlled with tACS: Implementation and Applications

    PubMed Central

    ten Oever, Sanne; de Graaf, Tom A.; Bonnemayer, Charlie; Ronner, Jacco; Sack, Alexander T.; Riecke, Lars

    2016-01-01

    In recent years, it has become increasingly clear that both the power and phase of oscillatory brain activity can influence the processing and perception of sensory stimuli. Transcranial alternating current stimulation (tACS) can phase-align and amplify endogenous brain oscillations and has often been used to control and thereby study oscillatory power. Causal investigation of oscillatory phase is more difficult, as it requires precise real-time temporal control over both oscillatory phase and sensory stimulation. Here, we present hardware and software solutions allowing temporally precise presentation of sensory stimuli during tACS at desired tACS phases, enabling causal investigations of oscillatory phase. We developed freely available and easy to use software, which can be coupled with standard commercially available hardware to allow flexible and multi-modal stimulus presentation (visual, auditory, magnetic stimuli, etc.) at pre-determined tACS-phases, opening up a range of new research opportunities. We validate that stimulus presentation at tACS phase in our setup is accurate to the sub-millisecond level with high inter-trial consistency. Conventional methods investigating the role of oscillatory phase such as magneto-/electroencephalography can only provide correlational evidence. Using brain stimulation with the described methodology enables investigations of the causal role of oscillatory phase. This setup turns oscillatory phase into an independent variable, allowing innovative, and systematic studies of its functional impact on perception and cognition. PMID:27803651

  11. Probing the causal role of prestimulus interregional synchrony for perceptual integration via tACS

    PubMed Central

    Stonkus, Rolandas; Braun, Verena; Kerlin, Jess R.; Volberg, Gregor; Hanslmayr, Simon

    2016-01-01

    The phase of prestimulus oscillations at 7–10 Hz has been shown to modulate perception of briefly presented visual stimuli. Specifically, a recent combined EEG-fMRI study suggested that a prestimulus oscillation at around 7 Hz represents open and closed windows for perceptual integration by modulating connectivity between lower order occipital and higher order parietal brain regions. We here utilized brief event-related transcranial alternating current stimulation (tACS) to specifically modulate this prestimulus 7 Hz oscillation, and the synchrony between parietal and occipital brain regions. To this end we tested for a causal role of this particular prestimulus oscillation for perceptual integration. The EEG was acquired at the same time allowing us to investigate frequency specific after effects phase-locked to stimulation offset. On a behavioural level our results suggest that tACS did modulate perceptual integration, however, in an unexpected manner. On an electrophysiological level our results suggest that brief tACS does induce oscillatory entrainment, as visible in frequency specific activity phase-locked to stimulation offset. Together, our results do not strongly support a causal role of prestimulus 7 Hz oscillations for perceptual integration. However, our results suggest that brief tACS is capable of modulating oscillatory activity in a temporally sensitive manner. PMID:27616188

  12. Epidermal expression of I-TAC (Cxcl11) instructs adaptive Th2-type immunity.

    PubMed

    Roebrock, Kirsten; Sunderkötter, Cord; Münck, Niels-Arne; Wolf, Marc; Nippe, Nadine; Barczyk, Katarzyna; Varga, Georg; Vogl, Thomas; Roth, Johannes; Ehrchen, Jan

    2014-04-01

    To decipher early promoters of the local microenvironment for Th2-type immunity, we wanted to identify gene patterns that were induced by Leishmania major in the infected skin of susceptible, Th2-prone BALB/c, but not of resistant, Th1-prone C57BL/6 mice. We found a marked up-regulation of the chemokine I-TAC (Cxcl11) during the first 2 d of infection in the epidermis of susceptible but not of resistant mice. Accordingly, local injection of I-TAC (2×1 μg) in resistant mice on the first day of infection resulted in a Th2-driven, sustained deterioration of disease and dramatically enhanced parasite levels. On the cellular level, I-TAC decreased IL-12 production by dendritic cells (DCs) in skin-draining lymph nodes and by DCs in vitro. Thus, we demonstrate for the first time that epidermis-derived I-TAC triggers a sustained Th2-response that determines the outcome of a complex immunological process.

  13. Influence of additions of nanoparticles TaC on a microstructure laser cladding

    NASA Astrophysics Data System (ADS)

    Murzakov, M. A.; Petrovskiy, V. N.; Polski, V. I.; Mironov, V. D.; Prokopova, N. M.; Tret'yakov, E. V.

    2015-03-01

    The features of a laser cladding of nickel-based powders with TaC nanopowder additives have been experimentally investigated. The minimum depth of pro-melting of a basis, microhardness distribution over the cross section of the substrate, and the saturation of the metal of the cladding with basis components has been determined in the experiments.

  14. Differentiation through Choice: Using a Think-Tac-Toe for Science Content

    ERIC Educational Resources Information Center

    Dotger, Sharon; Causton-Theoharis, Julie

    2010-01-01

    Differentiation can begin with a single lesson, expand to a unit, and finally grow to be a natural part of a teacher's daily practice. The Think-Tac-Toe, described in this article, can evaluate students' learning during and at the conclusion of a unit. Prior to its creation, teachers should preassess students to be certain that the content of the…

  15. Tic Tac TOE: Effects of Predictability and Importance on Acoustic Prominence in Language Production

    ERIC Educational Resources Information Center

    Watson, Duane G.; Arnold, Jennifer E.; Tanenhaus, Michael K.

    2008-01-01

    Importance and predictability each have been argued to contribute to acoustic prominence. To investigate whether these factors are independent or two aspects of the same phenomenon, naive participants played a verbal variant of Tic Tac Toe. Both importance and predictability contributed independently to the acoustic prominence of a word, but in…

  16. A merged quadrupole-calorimeter for CEPC

    NASA Astrophysics Data System (ADS)

    Talman, Richard; Hauptman, John

    2016-11-01

    The luminosity ℒ of colliding beams in a storage ring such as CEPC depends strongly on l∗, the half-length of the free space centered on the intersection point (IP). l∗ is also the length from the IP to the front edges of the two near-in quadrupoles that are focusing the counter-circulating beams to the IP spot. The detector length cannot, therefore, exceed 2l∗. Since ℒ increases strongly with decreasing l∗, there is incentive for reducing l∗; but this requires the detector to be shorter than desirable. This paper proposes a method for integrating these adjacent quadrupoles into the particle detector to retain (admittedly degraded) active particle detection of those forward going particles that would otherwise be obscured by the quadrupole. A gently conical quadrupole shape is more natural for merging the quadrupole into the particle detector than is the analytically exact cylindrical shape. This is true whether or not the calorimeter is integrated. It will be the task of accelerator physicists to determine the extent to which deviation from the pure quadrupole field compromises (or improves) accelerator performance. Superficially, both the presence of strongest gradient close to the IP and largest aperture farther from the IP seem to be advantageous. A tentative design for this merged, quadrupole-calorimeter is given.

  17. High total antioxidant capacity of the porcine seminal plasma (SP-TAC) relates to sperm survival and fertility.

    PubMed

    Barranco, Isabel; Tvarijonaviciute, Asta; Perez-Patiño, Cristina; Parrilla, Inmaculada; Ceron, Jose J; Martinez, Emilio A; Rodriguez-Martinez, Heriberto; Roca, Jordi

    2015-12-21

    The study attempted to clarify the role of total antioxidant capacity of seminal plasma (SP-TAC) on boar sperm survival and fertility after artificial insemination (AI). SP-TAC differed (P < 0.001) among boars (n° = 15) and, to a lesser degree, among ejaculates within male (4 ejaculates/boar). SP-TAC also differed (P < 0.001) among ejaculate fractions (43 ejaculates and 3 fractions per ejaculate), of which the sperm-peak portion of the sperm rich ejaculate fraction (SRF) had the highest SP-TAC. SP-TAC was not correlated with sperm quality (motility and viability) or functionality (intracellular ROS generation and lipid peroxidation) of liquid AI-semen samples stored at 17 °C for 72 h (90 AI-samples), but the decline in sperm quality was larger (P < 0.05) in ejaculates with low, compared with high SP-TAC (hierarchically grouped). The SP-TAC differences among ejaculate portions agree with sperm cryosurvival rates (14 ejaculates from 7 boars), showing sperm from sperm-peak portion better (P < 0.01) post-thaw quality and functionality than those from the entire ejaculate (mainly post-SRF). Boars (n° = 18) with high SP-TAC (hierarchically grouped) had higher (P < 0.05) fertility outcomes (5,546 AI-sows) than those with low SP-TAC. Measurement of SP-TAC ought to be a discriminative tool to prognosis fertility in breeding boars.

  18. High total antioxidant capacity of the porcine seminal plasma (SP-TAC) relates to sperm survival and fertility

    PubMed Central

    Barranco, Isabel; Tvarijonaviciute, Asta; Perez-Patiño, Cristina; Parrilla, Inmaculada; Ceron, Jose J.; Martinez, Emilio A.; Rodriguez-Martinez, Heriberto; Roca, Jordi

    2015-01-01

    The study attempted to clarify the role of total antioxidant capacity of seminal plasma (SP-TAC) on boar sperm survival and fertility after artificial insemination (AI). SP-TAC differed (P < 0.001) among boars (n° = 15) and, to a lesser degree, among ejaculates within male (4 ejaculates/boar). SP-TAC also differed (P < 0.001) among ejaculate fractions (43 ejaculates and 3 fractions per ejaculate), of which the sperm-peak portion of the sperm rich ejaculate fraction (SRF) had the highest SP-TAC. SP-TAC was not correlated with sperm quality (motility and viability) or functionality (intracellular ROS generation and lipid peroxidation) of liquid AI-semen samples stored at 17 °C for 72 h (90 AI-samples), but the decline in sperm quality was larger (P < 0.05) in ejaculates with low, compared with high SP-TAC (hierarchically grouped). The SP-TAC differences among ejaculate portions agree with sperm cryosurvival rates (14 ejaculates from 7 boars), showing sperm from sperm-peak portion better (P < 0.01) post-thaw quality and functionality than those from the entire ejaculate (mainly post-SRF). Boars (n° = 18) with high SP-TAC (hierarchically grouped) had higher (P < 0.05) fertility outcomes (5,546 AI-sows) than those with low SP-TAC. Measurement of SP-TAC ought to be a discriminative tool to prognosis fertility in breeding boars. PMID:26688188

  19. The peculiar heme pocket of the 2/2 hemoglobin of cold-adapted Pseudoalteromonas haloplanktis TAC125.

    PubMed

    Howes, Barry D; Giordano, Daniela; Boechi, Leonardo; Russo, Roberta; Mucciacciaro, Simona; Ciaccio, Chiara; Sinibaldi, Federica; Fittipaldi, Maria; Martí, Marcelo A; Estrin, Darío A; di Prisco, Guido; Coletta, Massimo; Verde, Cinzia; Smulevich, Giulietta

    2011-02-01

    The genome of the cold-adapted bacterium Pseudoalteromonas haloplanktis TAC125 contains multiple genes encoding three distinct monomeric hemoglobins exhibiting a 2/2 α-helical fold. In the present work, one of these hemoglobins is studied by resonance Raman, electronic absorption and electronic paramagnetic resonance spectroscopies, kinetic measurements, and different bioinformatic approaches. It is the first cold-adapted bacterial hemoglobin to be characterized. The results indicate that this protein belongs to the 2/2 hemoglobin family, Group II, characterized by the presence of a tryptophanyl residue on the bottom of the heme distal pocket in position G8 and two tyrosyl residues (TyrCD1 and TyrB10). However, unlike other bacterial hemoglobins, the ferric state, in addition to the aquo hexacoordinated high-spin form, shows multiple hexacoordinated low-spin forms, where either TyrCD1 or TyrB10 can likely coordinate the iron. This is the first example in which both TyrCD1 and TyrB10 are proposed to be the residues that are alternatively involved in heme hexacoordination by endogenous ligands.

  20. High-sensitivity microfluidic calorimeters for biological and chemical applications

    PubMed Central

    Lee, Wonhee; Fon, Warren; Axelrod, Blake W.; Roukes, Michael L.

    2009-01-01

    High-sensitivity microfluidic calorimeters raise the prospect of achieving high-throughput biochemical measurements with minimal sample consumption. However, it has been challenging to realize microchip-based calorimeters possessing both high sensitivity and precise sample-manipulation capabilities. Here, we report chip-based microfluidic calorimeters capable of characterizing the heat of reaction of 3.5-nL samples with 4.2-nW resolution. Our approach, based on a combination of hard- and soft-polymer microfluidics, provides both exceptional thermal response and the physical strength necessary to construct high-sensitivity calorimeters that can be scaled to automated, highly multiplexed array architectures. Polydimethylsiloxane microfluidic valves and pumps are interfaced to parylene channels and reaction chambers to automate the injection of analyte at 1 nL and below. We attained excellent thermal resolution via on-chip vacuum encapsulation, which provides unprecedented thermal isolation of the minute microfluidic reaction chambers. We demonstrate performance of these calorimeters by resolving measurements of the heat of reaction of urea hydrolysis and the enthalpy of mixing of water with methanol. The device structure can be adapted easily to enable a wide variety of other standard calorimeter operations; one example, a flow calorimeter, is described. PMID:19706406

  1. Method and system for improved resolution of a compensated calorimeter detector

    DOEpatents

    Dawson, John W.

    1991-01-01

    An improved method and system for a depleted uranium calorimeter detector used in high energy physics experiments. In a depleted uranium calorimeter detector, the energy of a particle entering the calorimeter detector is determined and the output response of the calorimeter detector is compensated so that the ratio of the integrated response of the calorimeter detector from a lepton to the integrated response of the calorimeter detector from a hadron of the same energy as the lepton is approximately equal to 1. In the present invention, the energy of a particle entering the calorimeter detector is determined as a function of time and the hadron content of the response of the calorimeter detector is inferred based upon the time structure of the energy pulse measured by the calorimeter detector. The energy measurement can be corrected based on the inference of the hadron content whereby the resolution of the calorimeter can be improved.

  2. The calcineurin dependent transcription factor TacA is involved in development and the stress response of Dictyostelium discoideum.

    PubMed

    Thewes, Sascha; Krohn, Stefanie; Schmith, Anika; Herzog, Sergej; Stach, Thomas; Weissenmayer, Barbara; Mutzel, Rupert

    2012-10-01

    Calcineurin is an important signalling protein in a plethora of Ca(2+)-regulated cellular processes. In contrast to what is known about the function of calcineurin in various organisms, information on calcineurin substrates is still limited. Here we describe the identification and characterisation of the transcription factor activated by calcineurin (TacA) in the model organism Dictyostelium discoideum. TacA is a putative zinc-finger transcription factor orthologue of yeast Crz1. In resting unstimulated cells the protein is located in the cytosol and translocates to the nucleus in a calcineurin-dependent manner after Ca(2+)-stimulation. Nuclear export of TacA is partially dependent on GskA, the Dictyostelium orthologue of mammalian GSK3. The expression of tacA is developmentally regulated with its kinetics roughly paralleling calcineurin regulation. Silencing of tacA via RNAi leads to developmental defects and dysregulation of developmentally regulated and Ca(2+)-regulated marker genes. Additionally, TacA is involved in the stress response of D. discoideum during development in a separate pathway to the well-known stress response in Dictyostelium via STATc. Finally we provide evidence that TacA is not only an orthologue of yeast Crz1 but also functionally related to mammalian NFAT.

  3. Phase Dependency of the Human Primary Motor Cortex and Cholinergic Inhibition Cancelation During Beta tACS

    PubMed Central

    Guerra, Andrea; Pogosyan, Alek; Nowak, Magdalena; Tan, Huiling; Ferreri, Florinda; Di Lazzaro, Vincenzo; Brown, Peter

    2016-01-01

    The human motor cortex has a tendency to resonant activity at about 20 Hz so stimulation should more readily entrain neuronal populations at this frequency. We investigated whether and how different interneuronal circuits contribute to such resonance by using transcranial magnetic stimulation (TMS) during transcranial alternating current stimulation (tACS) at motor (20 Hz) and a nonmotor resonance frequency (7 Hz). We tested different TMS interneuronal protocols and triggered TMS pulses at different tACS phases. The effect of cholinergic short-latency afferent inhibition (SAI) was abolished by 20 Hz tACS, linking cortical beta activity to sensorimotor integration. However, this effect occurred regardless of the tACS phase. In contrast, 20 Hz tACS selectively modulated MEP size according to the phase of tACS during single pulse, GABAAergic short-interval intracortical inhibition (SICI) and glutamatergic intracortical facilitation (ICF). For SICI this phase effect was more marked during 20 Hz stimulation. Phase modulation of SICI also depended on whether or not spontaneous beta activity occurred at ~20 Hz, supporting an interaction effect between tACS and underlying circuit resonances. The present study provides in vivo evidence linking cortical beta activity to sensorimotor integration, and for beta oscillations in motor cortex being promoted by resonance in GABAAergic interneuronal circuits. PMID:27522077

  4. Data Analysis for the Scintillating Optical Fiber Calorimeter (SOFCAL)

    NASA Technical Reports Server (NTRS)

    Christl, Mark J.

    1997-01-01

    The scintillating optical fiber calorimeter is a hybrid instrument with both active and passive components for measuring the proton and helium cosmic ray spectra from 0.2 to IO TeV kinetic energy. A thin emulsion/x-ray film chamber is situated between a cerenkov counter and an imaging calorimeter. Scintillating optical fibers sample the electromagnetic showers that develop in the calorimeter and identify the trajectory of cosmic rays that interact in SOFCAL. The emulsion/x-ray film data provide an in flight calibration for SOFCAL. The data reduction techniques used will be discussed and interim results of the analysis from a 20 hour balloon flight will be presented.

  5. New tools for the simulation and design of calorimeters

    SciTech Connect

    Womersley, W.J.

    1989-07-10

    Two new approaches to the simulation and design of large hermetic calorimeters are presented. Firstly, the Shower Library scheme used in the fast generation of showers in the Monte Carlo of the calorimeter for the D-Zero experiment at the Fermilab Tevatron is described. Secondly, a tool for the design future calorimeters is described, which can be integrated with a computer aided design system to give engineering designers an immediate idea of the relative physics capabilities of different geometries. 9 refs., 6 figs., 1 tab.

  6. Optical System of the STAR Barrel Electromagnetic Calorimeter

    NASA Astrophysics Data System (ADS)

    Grachov, O. A.

    2000-04-01

    The STAR Barrel Electromagnetic Calorimeter(BEMC) is a sampling calorimeter and the core of structure consist of a lead-scintillator plate stack. The plastic scintillator in the form of Mega-tile with 40 optically isolated tiles in each layer. The tile/fiber system uses a wavelength shifting fiber to read out the signal of a tile and a optical clear fiber carry the light through the magnet structure to the electronic-PMT box. A discription of the Optical system of BEMC is presented along with a current status of the quality control program of the calorimeter production.

  7. D0 Silicon Upgrade: End Calorimeter Transfer Bridge Modification

    SciTech Connect

    Stredde, H.J.; /Fermilab

    1996-07-10

    During the assembly of major components into the D0 Detector, a transfer bridge was required to move the North-End Calorimeter from the clean room,over the cable bridge and onto the north sidewalk of the assembly hall. This experiment is now at the beginning stages of the next phase, namely the upgrade of this Detector for future physics research. A major piece of this upgrade is the installation of a solenoid magnet into the Central Calorimeter. In order to accomplish this, the South End Calorimeter has to be removed from the detector and the North End Calorimeter must be moved an additional 20-inch from its nominal open position (total 60-inch movement). The South End Calorimeter will be removed from the detector using the equipment designed for its installation. The calorimeter will be staged on the south sidewalk during the installation of the solenoid magnet and the central tracking systems. The North End Calorimeter is moved 60-inch to give more space between calorimeters during magnet, tracker and cable installation work. This movement will allow the calorimeter to remain coupled to the cryo system. However, this movement requires an extension be added to the center beam. This extension will support the rear wheels of the calorimeter and in the case of the end calorimeters, carry the majority of the weight. The extension is to be a modification of the transfer bridge. This modification, basically has T1 steel blocks added to one end and legs to the sidewalk supports at the other. The T1 steel blocks are notched to fit into the center beam porches and are welded to bridge rails. This design is the same as that for the installation bridge (3740.312-ME-273456), including the welds and weld procedures which are identical in both cases. Since load testing is impractical, the critical welds will be non-destructive tested by ultrasonic means. The laboratory, through the FESS Department, has a contract with M.Q.S. Inspection Inc. The results of this testing will be

  8. sPHENIX Calorimeter Design and Jet Performance

    SciTech Connect

    Haggerty J. S.

    2016-09-27

    The PHENIX collaboration is planning a detector upgrade, sPHENIX, which consists of large acceptance calorimetry and tracking detectors built around the superconducting solenoid recently shipped to Brookhaven from the decommissioned BaBar experiment at SLAC. The sPHENIX calorimeter system includes three radial layers of samplingcalorimeters, a tungsten-scintillating fiber electromagnetic calorimeter, and two longitudinally segmented samplinghadron calorimeters that are made of scintillator tiles and steel plates. Together, they provide hermetic coverage in n < 1 for calorimetry based jet measurements as well as minimal bias jet trigger capability, which coupled with high resolution tracking, enable an extremely rich jet physics program at RHIC.

  9. Trigger circuits for the PHENIX electromagnetic calorimeter

    SciTech Connect

    Frank, S.S.; Britton, C.L. Jr.; Winterberg, A.L.; Young, G.R.

    1997-11-01

    Monolithic and discrete circuits have been developed to provide trigger signals for the PHENIX electromagnetic calorimeter detector. These trigger circuits are deadtimeless and create overlapping 4 by 4 energy sums, a cosmic muon trigger, and a 144 channel energy sum. The front end electronics of the PHENIX system sample the energy and timing channels at each bunch crossing (BC) but it is not known immediately if this data is of interest. The information from the trigger circuits is used to determine if the data collected is of interest and should be digitized and stored or discarded. This paper presents details of the design, issues affecting circuit performance, characterization of prototypes fabricated in 1.2 {micro}m Orbit CMOS, and integration of the circuits into the EMCal electronics system.

  10. SCA controller for the ATLAS calorimeter

    SciTech Connect

    Gingrich, D.M.; Hewlett, J.C.; Holm, L.

    1997-12-31

    The front-end readout of the ATLAS liquid argon calorimeter will store data locally in analog pipeline memories at the LHC beam crossing frequency of 40 MHz. Switched capacitor array chips meeting the ATLAS readout requirements will be used. These new chips axe capable of simultaneous read and write operations, and allow random access to storage locations. To utilize these essential design features requires a substantial amount of fast control and address bookkeeping logic. We have designed a controller capable of operating the pipelines as analog random access memories and that satisfies the ATLAS readout requirements. The pipeline controller manages the data of 144 time samples and can operate at a mean trigger rate of about 75 kHz, when reading out five time samples per event. We are currently prototyping an integrated version of the controller implemented in a FPGA from Xilinx.

  11. Calorimeter Simulation with Hadrons in CMS

    SciTech Connect

    Piperov, Stefan; /Sofiya, Inst. Nucl. Res. /Fermilab

    2008-11-01

    CMS is using Geant4 to simulate the detector setup for the forthcoming data from the LHC. Validation of physics processes inside Geant4 is a major concern in view of getting a proper description of jets and missing energy for signal and background events. This is done by carrying out an extensive studies with test beam using the prototypes or real detector modules of the CMS calorimeter. These data are matched with Geant4 predictions using the same framework that is used for the entire CMS detector. Tuning of the Geant4 models is carried out and steps to be used in reproducing detector signals are defined in view of measurements of energy response, energy resolution, transverse and longitudinal shower profiles for a variety of hadron beams over a broad energy spectrum between 2 to 300 GeV/c. The tuned Monte Carlo predictions match many of these measurements within systematic uncertainties.

  12. Advanced Thin Ionization Calorimeter (ATIC) Balloon Experiment

    NASA Technical Reports Server (NTRS)

    Wefel, John P.; Guzik, T. Gregory

    2001-01-01

    During grant NAG5-5064, Louisiana State University (LSU) led the ATIC team in the development, construction, testing, accelerator validation, pre-deployment integration and flight operations of the Advanced Thin Ionization Calorimeter (ATIC) Balloon Experiment. This involved interfacing among the ATIC collaborators (UMD, NRL/MSFC, SU, MSU, WI, SNU) to develop a new balloon payload based upon a fully active calorimeter, a carbon target, a scintillator strip hodoscope and a pixilated silicon solid state detector for a detailed investigation of the very high energy cosmic rays to energies beyond 10(exp 14) eV/nucleus. It is in this very high energy region that theory predicts changes in composition and energy spectra related to the Supernova Remnant Acceleration model for cosmic rays below the "knee" in the all-particle spectrum. This report provides a documentation list, details the anticipated ATIC science return, describes the particle detection principles on which the experiment is based, summarizes the simulation results for the system, describes the validation work at the CERN SPS accelerator and details the balloon flight configuration. The ATIC experiment had a very successful LDB flight from McMurdo, Antarctica in 12/00 - 1/01. The instrument performed well for the entire 15 days. Preliminary data analysis shows acceptable charge resolution and an all-particle power law energy deposition distribution not inconsistent with previous measurements. Detailed analysis is underway and will result in new data on the cosmic ray charge and energy spectra in the GeV - TeV energy range. ATIC is currently being refurbished in anticipation of another LDB flight in the 2002-03 period.

  13. Distribution of lymphocytes with interleukin-2 receptors (TAC antigens) in reactive lymphoproliferative processes, Hodgkin's disease, and non-Hodgkin's lymphomas. An immunohistologic study of 300 cases.

    PubMed Central

    Sheibani, K.; Winberg, C. D.; van de Velde, S.; Blayney, D. W.; Rappaport, H.

    1987-01-01

    The authors investigated the distribution of interleukin-2 receptors (TAC antigen) in the lymph nodes of 300 patients with lymphoproliferative disorders. They used fresh-frozen sections to evaluate a possible correlation between the immunophenotype of specific lymphoid disorders and the presence or absence of TAC expression and to determine whether the TAC positivity of lymphoid cells contributes to the characterization of lymphoproliferative processes. All of the cases had previously been studied with a large screening panel of monoclonal antibodies and polyclonal antisera. Among 85 patients with a variety of benign reactive processes, the lymph nodes from 47 contained TAC-bearing lymphocytes in various patterns of distribution. Of 41 patients with Hodgkin's disease, 37 had TAC-bearing lymphocytes. Of 26 B-cell, well-differentiated lymphocytic lymphomas (WDL), 14 were diffusely TAC-positive and one had TAC-bearing cells in random distribution. Six cases of intermediate lymphocytic lymphoma were also studied, and three showed randomly distributed TAC-bearing lymphocytes. Of 19 patients with follicular or follicular and diffuse, poorly differentiated lymphocytic (PDL) lymphoma, 14 were TAC-positive. All 3 diffuse PDL lymphomas studied were TAC-negative. Among 23 cases of B-cell and 5 cases of T-cell mixed cell lymphoma, 15 and three, respectively, had TAC-positive lymphocytes. Of 39 large cell lymphomas (B-cell, 33; T-cell, 6), 14 were TAC-positive. All 13 cases of hairy cell leukemia were diffusely positive. Of 23 T-lymphoblastic lymphomas, only 1 showed positive TAC reactivity, which was focal. Of 5 cases of cutaneous T-cell lymphoma, 2 had TAC-bearing lymphocytes. Our study indicates that the TAC antigen is not lineage-specific, and that it may be expressed by lymphoid cells regardless of their phenotype. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 PMID:3105322

  14. Calibration of a digital hadron calorimeter with muons

    SciTech Connect

    Bilki, Burak; Butler, John; Cundiff, Tim; Drake, Gary; Haberichter, William; Hazen, Eric; Hoff, Jim; Holm, Scott; Kreps, Andrew; May, Ed; Mavromanolakis, Georgios; /Fermilab /Iowa U. /Argonne /Boston U. /Argonne, PHY

    2008-02-01

    The calibration procedure of a finely granulated digital hadron calorimeter with Resistive Plate Chambers as the active elements is described. Results obtained with a stack of nine layers exposed to muons from the Fermilab test beam are presented.

  15. The BaBar cesium iodide electromagnetic calorimeter

    SciTech Connect

    Wuest, C.R.

    1994-12-01

    The BABAR Cesium Iodide Electromagnetic Calorimeter is currently in the technical design stage. The calorimeter consists of approximately 10,000 individual thallium-doped cesium iodide crystals arranged in a near-hermetic barrel and endcap structure. Taking previous cesium iodide calorimeters as a benchmark, we hope to build a system with roughly two times better energy resolution. This will be achieved by a combination of high quality crystal growing, precision mechanical processing of crystals and support structure, highly efficient light collection and low noise readout electronics. The calorimeter described here represents the current state of the design and we are undertaking an active period of optimization before this design is finalized. We discuss here the physics motivation, the current design and options for optimization.

  16. The Forward Calorimeter of the GlueX Experiment

    NASA Astrophysics Data System (ADS)

    Bennett, Daniel; GlueX Collaboration

    2013-10-01

    The Forward Calorimeter (FCAL) of the GlueX experiment is a lead glass electromagnetic calorimeter currently being built in Hall D of Jefferson Lab. The GlueX experiment is a photoproduction experiment that will utilize coherent bremsstrahlung radiation to map out the light meson spectrum, including a search for hybrid mesons with exotic quantum numbers (JPC). The FCAL will detect photons between 1° and 10 .8° downstream from the target. The calorimeter is built out of 2800 elements, each of which consists of a lead glass block, an FEU 84-3 PMT, and a custom Cockcroft-Walton electronic base. In the Fall of 2011, a 25 element prototype detector was installed in Hall B of Jefferson Lab to measure the energy and timing resolution of the calorimeter using electrons between 100 and 250 MeV. The design and construction of FCAL and the results from the prototype test will be discussed.

  17. Macintosh II based space Telemetry and Command (MacTac) system

    NASA Technical Reports Server (NTRS)

    Dominy, Carol T.; Chesney, James R.; Collins, Aaron S.; Kay, W. K.

    1991-01-01

    The general architecture and the principal functions of the Macintosh II based Telemetry and Command system, presently under development, are described, with attention given to custom telemetry cards, input/output interfaces, and the icon driven user interface. The MacTac is a low-cost, transportable, easy to use, compact system designed to meet the requirements specified by the Consultative Committeee for Space Data Systems while remaining flexible enough to support a wide variety of other user specific telemetry processing requirements, such as TDM data. In addition, the MacTac can accept or generate forward data (such as spacecraft commands), calculate and append a Polynomial Check Code, and output these data to NASCOM to provide full Telemetry and Command capability.

  18. TacSat-2: Path finder for a Close Space Support Asset

    NASA Astrophysics Data System (ADS)

    Bhopale, A.; Finley, C.

    2008-08-01

    With th e launch of TacSat-2, the Oper ationally Responsive Sp ace (O RS) commun ity had its f irst on- orbit asset and opportunity to prove or disprove the premise that small, in expensiv e, and quickly constructed spacecraf t could perform useful operation al missions when needed and for as long as need ed. All of the components of the comp lex TacSat-2 system had to work together to answer the basic questions, "In a crisis, can a lab-developed spacecraf t and ground architecture competen tly p erform th e mission of systems that cost twen ty times the price and tak e four times as long to develop? Mor eover, can th is system actu ally improve on the responsiveness of Nation al Systems to a certain set of underserv ed Oper ational customers?" When all w as said and done, TacSat-2 was a sp acecraf t that h ad to: 1) Carry th irteen tactical and scientific payloads to orbit, many of which doubled as essen tial, non-redundant subsystems; 2) Launch from an unproven launch base on a last minute "rep lacement" launch vehicle; and 3) Fulfill about 140 on-orbit mission requirements. It had tactical sensors, two unproven communication links, numerous next-gen eration single- string componen ts (e.g., h igh-efficiency propulsion system, thin-film so lar arrays, low-power versatile star camera) , and autonomous softw are to mak e the system more friendly and familiar to Tactical, rather than Spacecraf t Op erators. However, the mission was as mu ch about the implementation as it w as about the components. TacSat-2 was designed for and emp loyed with a different concept of operations ( CONOPS) than tradition al N ational Operational Assets. It w as designed to be th e fir st-ev er Clo se Space Support platform and operated in a manner more analogous to Close Air Support aircraf t than to tr aditional spacecraft. Therefore, th e primary objective of the TacSat-2 mission was to use th e TacSat-2 system to id entify those parts of the spacecr aft, ground system, and CON OPS

  19. Marginal Bidding: An Application of the Equimarginal Principle to Bidding in TAC SCM

    NASA Astrophysics Data System (ADS)

    Greenwald, Amy; Naroditskiy, Victor; Odean, Tyler; Ramirez, Mauricio; Sodomka, Eric; Zimmerman, Joe; Cutler, Clark

    We present a fast and effective bidding strategy for the Trading Agent Competition in Supply Chain Management (TAC SCM). In TAC SCM, manufacturers compete to procure computer parts from suppliers (the procurement problem), and then sell assembled computers to customers in reverse auctions (the bidding problem). This paper is concerned only with bidding, in which an agent must decide how many computers to sell and at what prices to sell them. We propose a greedy solution, Marginal Bidding, inspired by the Equimarginal Principle, which states that revenue is maximized among possible uses of a resource when the return on the last unit of the resource is the same across all areas of use. We show experimentally that certain variations of Marginal Bidding can compute bids faster than our ILP solution, which enables Marginal Bidders to consider future demand as well as current demand, and hence achieve greater revenues when knowledge of the future is valuable.

  20. Comparison of Tacrolimus and Sirolimus (Tac/Sir) versus Tacrolimus, Sirolimus, and mini-methotrexate (Tac/Sir/MTX) as acute graft-versus-host disease prophylaxis after reduced-intensity conditioning allogeneic peripheral blood stem cell transplantation.

    PubMed

    Ho, Vincent T; Aldridge, Julie; Kim, Haesook T; Cutler, Corey; Koreth, John; Armand, Philippe; Antin, Joseph H; Soiffer, Robert J; Alyea, Edwin P

    2009-07-01

    Previous studies have shown that adding sirolimus to a tacrolimus/mini-methotrexate regimen (Tac/Sir/MTX) as graft-versus-host disease (GVHD) prophylaxis produces low rates of acute GVHD (aGVHD) after reduced-intensity conditioning (RIC) allogeneic stem cell transplantation (SCT). To assess whether posttransplantation methotrexate MTX can be safely eliminated altogether, we conducted a prospective clinical trial testing the combination of T and Sir alone (tac/sir) as GVHD prophylaxis after RIC SCT from matched related donors. We compared the results with patients who received (Tac/Sir/MTX) as GVHD prophylaxis after RIC SCT from matched related donors in a previous prospective study. Patients in both groups received i.v. fludarabine (Flu) 30 mg/m(2)/day and i.v. busulfan (Bu) 0.8 mg/kg/day on days -5 to -2 as conditioning, followed by transplantation of unmanipulated filgrastim-mobilized peripheral blood stem cells (PBSCS). After transplantation, patients in both groups received Tac and Sir orally starting on day -3, with doses adjusted to achieve trough serum levels of 5 to 10 ng/mL and 3 to 12 ng/mL, respectively. The patients in the Tac/Sir/MTX group also received mini-MTX therapy (5 mg/m(2) i.v.) on days +1, +3, and +6. Filgrastim 5 microg/kg/day s.c. was started on day +1 and continued until neutrophil engraftment. Twenty-nine patients received the Tac/Sir regimen, and 46 patients received the Tac/Sir/MTX regimen. The 2 groups were balanced in terms of age, sex, and disease characteristics. Engraftment was brisk and donor chimerism after transplantation robust in both groups. The cumulative incidence of grade II-IV aGVHD was similar in the 2 groups (17% for Tac/Sir versus 11% for Tac/Sir/MTX; P = .46). There also were no differences between the 2 groups in cumulative incidence of extensive chronic GVHD (cGVHD), treatment-related mortality (TRM), disease relapse, or survival. The Tac/Sir combination for GVHD prophylaxis is well tolerated and associated with a

  1. Playing Tic-Tac-Toe with a Sugar-Based Molecular Computer.

    PubMed

    Elstner, M; Schiller, A

    2015-08-24

    Today, molecules can perform Boolean operations and circuits at a level of higher complexity. However, concatenation of logic gates and inhomogeneous inputs and outputs are still challenging tasks. Novel approaches for logic gate integration are possible when chemical programming and software programming are combined. Here it is shown that a molecular finite automaton based on the concatenated implication function (IMP) of a fluorescent two-component sugar probe via a wiring algorithm is able to play tic-tac-toe.

  2. ATLAS Tile Calorimeter performance with Run 1 data

    NASA Astrophysics Data System (ADS)

    Cerdá Alberich, L.

    2016-07-01

    The performance of the central hadronic calorimeter, TileCal, in the ATLAS Experiment at the Large Hadron Collider is studied using cosmic-ray muons and the large sample of proton-proton collisions acquired during the Run 1 of LHC (2010-2012). Results are presented for the precision of the absolute energy scale and timing, noise characterization, and time-stability of the detector. The results show that the Tile Calorimeter performance is within the design requirements of the detector.

  3. Building and testing a high school calorimeter at CERN

    NASA Astrophysics Data System (ADS)

    Biesot, L.; Crane, R.; Engelen, M. A. G.; van Haren, A. M. A.; van Kleef, R. H. B.; Leenders, O. R.; Timmermans, C.

    2016-11-01

    We have designed, built and tested a crystal calorimeter in the context of CERN’s first beam line for schools competition. The results of the tests at CERN show that the light output of our calorimeter depends on the energy deposited by particles (electrons and muons) hitting the crystals. Our design can be reproduced by high schools around the world, as we have avoided the use of toxic chemicals.

  4. Vibration isolation system for cryogenic phonon-scintillation calorimeters

    NASA Astrophysics Data System (ADS)

    Lee, C.; Jo, H. S.; Kang, C. S.; Kim, G. B.; Kim, I.; Kim, S. R.; Kim, Y. H.; Lee, H. J.; So, J. H.; Yoon, Y. S.

    2017-02-01

    Cryogen-free dilution refrigerators are getting popular for rare event searches underground due to their advantages. However, the application of a pulse tube refrigerator introduces mechanical vibration that can translate into temperature fluctuation for calorimeters. The effect is significant in particular when the sensor is attached to a large absorber. A mechanical filter is installed to isolate the calorimeters from the vibration inside a cryogen-free dilution refrigerator while meeting thermal requirements.

  5. The electromagnetic calorimeter in JLab Real Compton Scattering Experiment

    SciTech Connect

    Albert Shahinyan; Eugene Chudakov; A. Danagoulian; P. Degtyarenko; K. Egiyan; V. Gorbenko; J. Hines; E. Hovhannisyan; Ch. Hyde; C.W. de Jager; A. Ketikyan; V. Mamyan; R. Michaels; A.M. Nathan; V. Nelyubin; I. Rachek; M. Roedelbrom; A. Petrosyan; R. Pomatsalyuk; V. Popov; J. Segal; Yu. Shestakov; J. Templon; H. Voskanyan; B. Wojtsekhowski

    2007-04-16

    A hodoscope calorimeter comprising of 704 lead-glass blocks is described. The calorimeter was constructed for use in the JLab Real Compton Scattering experiment. The detector provides a measurement of the coordinates and the energy of scattered photons in the GeV energy range with resolutions of 5 mm and 6\\%/$\\sqrt{E_\\gamma \\, [GeV]}$, respectively. Design features and performance parameters during the experiment are presented.

  6. Current Status and Performance of the BESIII Electromagnetic Calorimeter

    NASA Astrophysics Data System (ADS)

    Feldbauer, Florian; BESIII Collaboration

    2015-02-01

    The BESIII experiment is located at the Beijing Electron Positron Collider (BEPCII) in China. Its electromagnetic calorimeter (EMC) consists of 6240 CsI(TI) crystals, each read out by two Photodiodes (PD) at the end of the crystal. Changes in the response of the calorimeter due to radiation damage in the crystals or changes in the photo detector output are monitored with a light pulser system.

  7. Mapping entrained brain oscillations during transcranial alternating current stimulation (tACS).

    PubMed

    Witkowski, Matthias; Garcia-Cossio, Eliana; Chander, Bankim S; Braun, Christoph; Birbaumer, Niels; Robinson, Stephen E; Soekadar, Surjo R

    2016-10-15

    Transcranial alternating current stimulation (tACS), a non-invasive and well-tolerated form of electric brain stimulation, can influence perception, memory, as well as motor and cognitive function. While the exact underlying neurophysiological mechanisms are unknown, the effects of tACS are mainly attributed to frequency-specific entrainment of endogenous brain oscillations in brain areas close to the stimulation electrodes, and modulation of spike timing dependent plasticity reflected in gamma band oscillatory responses. tACS-related electromagnetic stimulator artifacts, however, impede investigation of these neurophysiological mechanisms. Here we introduce a novel approach combining amplitude-modulated tACS during whole-head magnetoencephalography (MEG) allowing for artifact-free source reconstruction and precise mapping of entrained brain oscillations underneath the stimulator electrodes. Using this approach, we show that reliable reconstruction of neuromagnetic low- and high-frequency oscillations including high gamma band activity in stimulated cortical areas is feasible opening a new window to unveil the mechanisms underlying the effects of stimulation protocols that entrain brain oscillatory activity.

  8. Solar Technology Acceleration Center (SolarTAC): Solar Resource & Meteorological Assessment Project (SOLRMAP); Aurora, Colorado (Data)

    DOE Data Explorer

    Wilcox, S.; Andreas, A.

    2011-02-11

    Located in Colorado, near Denver International Airport, SolarTAC is a private, member-based, 74-acre outdoor facility where the solar industry tests, validates, and demonstrates advanced solar technologies. SolarTAC was launched in 2008 by a public-private consortium, including Midwest Research Institute (MRI). As a supporting member of SolarTAC, the U.S. Department of Energy's National Renewable Energy Laboratory (NREL) has established a high quality solar and meteorological measurement station at this location. This Solar Resource and Meteorological Assessment Project (SOLRMAP) provides high quality measurements to support deployment of power projects in the United States. The no-funds-exchanged collaboration brings NREL solar resource assessment expertise together with industry needs for measurements. The end result is high quality data sets to support the financing, design, and monitoring of large scale solar power projects for industry in addition to research-quality data for NREL model development. NREL provides consultation for instrumentation and station deployment, along with instrument calibrations, data acquisition, quality assessment, data distribution, and summary reports. Industry participants provide equipment, infrastructure, and station maintenance.

  9. On-Orbit Results From the TacSat-2 ACTD Target Indicator Experiment AIS Payload

    NASA Astrophysics Data System (ADS)

    Duffey, T.; Huffine, C.; Nicholson, S.

    2008-08-01

    As part of the US Department of Defense's Operationally Responsive Space (ORS) initiative, the Naval Research Laboratory (NRL) developed the Target Indicator Experiment (TIE) payload for the TacSat-2 spacecraft, which was launched 16 December, 2006 on a Minotaur 1 launch vehicle from Wallops Island, Virginia. The TIE payload was an improved version of the primary payload developed for the TacSat-1 spacecraft. One of the main enhancements was the addition of a software definable radio receiver and demodulator for the collection of the Automated Identification System (AIS) signal now required globally on large ships for maritime safety and security. While several systems have been proposed, TacSat-2 was the first small satellite to successfully collect AIS signals from space. This paper presents an overview of the design of the TIE payload AIS system, the collection experiments that were performed during the life of the spacecraft, the results of those experiments, samples of the data collected, and recommendations for future systems.

  10. Energy Calibration of the Scintillating Optical Fiber Calorimeter Chamber (SOFCAL)

    NASA Technical Reports Server (NTRS)

    Christl, M. C.; Fountain, W. F.; Parnell, T.; Roberts, F. E.; Gregory, J. C.; Johnson, J.; Takahashi, Y.

    1997-01-01

    The Scintillating Optical Fiber Calorimeter (SOFCAL) detector is designed to make direct measures of the primary cosmic ray spectrum from -200 GeV/amu - 20 TeV/amu. The primary particles are resolved into groups according to their charge (p, He, CNO, Medium Z, Heavy Z) using both active and passive components integrated into the detector. The principal part of SOFCAL is a thin ionization calorimeter that measures the electromagnetic cascades that result from these energetic particles interacting in the detector. The calorimeter is divided into two sections: a thin passive emulsion/x-ray film calorimeter, and a fiber calorimeter that uses crossing layers of small scintillating optical fibers to sample the energy deposition of the cascades. The energy determination is made by fitting the fiber data to transition curves generated by Monte Carlo simulations. The fiber data must first be calibrated using the electron counts from the emulsion plates in the calorimeter for a small number of events. The technique and results of this calibration will be presented together with samples of the data from a balloon flight.

  11. An Imaging Calorimeter for Access-Concept Study

    NASA Technical Reports Server (NTRS)

    Parnell, T. A.; Adams, James H.; Binns, R. W.; Christl, M. J.; Derrickson, J. H.; Fountain, W. F.; Howell, L. W.; Gregory, J. C.; Hink, P. L.; Israel, M. H.; Whitaker, Ann F. (Technical Monitor)

    2001-01-01

    A mission concept study to define the "Advanced Cosmic-ray Composition Experiment for Space Station (ACCESS)" was sponsored by the National Aeronautics and Space Administration (NASA). The ACCESS instrument complement contains a transition radiation detector and an ionization calorimeter to measure tile spectrum of protons, helium, and heavier nuclei up to approximately 10(exp 15) eV to search for the limit of S/N shock wave acceleration, or evidence for other explanations of the spectra. Several calorimeter configurations have been studied, including the "baseline" totally active bismuth germanate instrument and sampling calorimeters utilizing various detectors. The Imaging Calorimeter for ACCESS (ICA) concept comprises a carbon target and a calorimeter using a high atomic number absorber sampled approximately each radiation length (rl) by thin scintillating fiber (SCIFI) detectors. The main features and options of the ICA instrument configuration are described in this paper. Since direct calibration is not possible over most of the energy range, the best approach must be decided from simulations of calorimeter performance extrapolated from CERN calibrations at 0.375 TeV. This paper presents results from the ICA simulations study.

  12. Measurements in large pool fires with an actively cooled calorimeter

    SciTech Connect

    Koski, J.A.; Wix, S.D.

    1995-12-31

    The pool fire thermal test described in Safety Series 6 published by the International Atomic Energy Agency (IAEA) or Title 10, Code of Federal Regulations, Part 71 (10CFR71) in the United States is one of the most difficult tests that a container for larger ``Type B`` quantities of nuclear materials must pass. If retests of a container are required, costly redesign and project delays can result. Accurate measurements and modeling of the pool fire environment will ultimately lower container costs by assuring that containers past the pool fire test on the first attempt. Experiments indicate that the object size or surface temperature of the container can play a role in determining local heat fluxes that are beyond the effects predicted from the simple radiative heat transfer laws. An analytical model described by Nicolette and Larson 1990 can be used to understand many of these effects. In this model a gray gas represents soot particles present in the flame structure. Close to the container surface, these soot particles are convectively and radiatively cooled and interact with incident energy from the surrounding fire. This cooler soot cloud effectively prevents some thermal radiation from reaching the container surface, reducing the surface heat flux below the value predicted by a transparent medium model. With some empirical constants, the model suggested by Nicolette and Larson can be used to more accurately simulate the pool fire environment. Properly formulated, the gray gas approaches also fast enough to be used with standard commercial computer codes to analyze shipping containers. To calibrate this type of model, accurate experimental measurements of radiative absorption coefficients, flame temperatures, and other parameters are necessary. A goal of the calorimeter measurements described here is to obtain such parameters so that a fast, useful design tool for large pool fires can be constructed.

  13. [An advanced metastatic breast cancer patient successfully treated with combination therapy including docetaxel, doxorubicin and cyclophosphamide (TAC) as salvage therapy].

    PubMed

    Sato, Yasushi; Takayama, Tetsuji; Sagawa, Tamotsu; Sato, Tsutomu; Okamoto, Kumiko; Takahashi, Shou; Abe, Seiichiro; Iyama, Satoshi; Murase, Kazuyuki; Kato, Junji; Niitsu, Yoshiro

    2008-03-01

    We reported here a case of advanced breast cancer successfully treated with combination therapy including docetaxel, doxorubicin and cyclophosphamide (TAC) as salvage therapy. A 56-year-old male was referred to our hospital for treatment of recurrent metastatic breast cancer. When he was admitted, his general condition was poor due to massive intraperitoneal metastasis. We administered TAC chemotherapy (docetaxel 75 mg/m(2), doxorubicin 50 mg/m(2), and cyclophosphamide 500 mg/m(2), every 3 weeks). During chemotherapy, he showed no major adverse effects except grade 3 neutropenia, which could be easily managed with G-CSF administration. Metastatic lesions almost disappeared after 4 cycles of TAC. TAC therapy was considered to be acceptable as salvage therapy for a metastatic male breast cancer patient.

  14. tACS Phase Locking of Frontal Midline Theta Oscillations Disrupts Working Memory Performance

    PubMed Central

    Chander, Bankim S.; Witkowski, Matthias; Braun, Christoph; Robinson, Stephen E.; Born, Jan; Cohen, Leonardo G.; Birbaumer, Niels; Soekadar, Surjo R.

    2016-01-01

    Background: Frontal midline theta (FMT) oscillations (4–8 Hz) are strongly related to cognitive and executive control during mental tasks such as memory processing, arithmetic problem solving or sustained attention. While maintenance of temporal order information during a working memory (WM) task was recently linked to FMT phase, a positive correlation between FMT power, WM demand and WM performance was shown. However, the relationship between these measures is not well understood, and it is unknown whether purposeful FMT phase manipulation during a WM task impacts FMT power and WM performance. Here we present evidence that FMT phase manipulation mediated by transcranial alternating current stimulation (tACS) can block WM demand-related FMT power increase (FMTΔpower) and disrupt normal WM performance. Methods: Twenty healthy volunteers were assigned to one of two groups (group A, group B) and performed a 2-back task across a baseline block (block 1) and an intervention block (block 2) while 275-sensor magnetoencephalography (MEG) was recorded. After no stimulation was applied during block 1, participants in group A received tACS oscillating at their individual FMT frequency over the prefrontal cortex (PFC) while group B received sham stimulation during block 2. After assessing and mapping phase locking values (PLV) between the tACS signal and brain oscillatory activity across the whole brain, FMT power and WM performance were assessed and compared between blocks and groups. Results: During block 2 of group A but not B, FMT oscillations showed increased PLV across task-related cortical areas underneath the frontal tACS electrode. While WM task-related FMTΔpower and WM performance were comparable across groups in block 1, tACS resulted in lower FMTΔpower and WM performance compared to sham stimulation in block 2. Conclusion: tACS-related manipulation of FMT phase can disrupt WM performance and influence WM task-related FMTΔpower. This finding may have important

  15. A role for Tac2, NkB and Nk3 receptor in normal and dysregulated fear memory consolidation

    PubMed Central

    Andero, Raül; Dias, Brian G.; Ressler, Kerry J

    2014-01-01

    Summary The centromedial amygdala (CeM), a subdivision of the central amygdala (CeA), is believed to be the main output station of the amygdala for fear expression. We provide evidence that the Tac2 gene, expressed by neurons specifically within the CeM, is required for modulating fear memories. Tac2 is colocalized with GAD65 and CaMKIIα but not with PKCd and Enk neurons in the CeM. Moreover, the Tac2 product, NkB, and its specific receptor, Nk3R, are also involved in the consolidation of fear memories. Increased Tac2 expression, through a stress-induced PTSD-like model, or following lentiviral CeA overexpression, are sufficient to enhance fear consolidation. This effect is blocked by the Nk3R antagonist, osanetant. Concordantly, silencing of Tac2-expressing neurons in CeA with DREADDs impairs fear consolidation. Together these studies provide a new understanding of the role of the Tac2 gene and CeM in fear processing and may provide novel approaches to intervention for fear-related disorders. PMID:24976214

  16. A role for Tac2, NkB, and Nk3 receptor in normal and dysregulated fear memory consolidation.

    PubMed

    Andero, Raül; Dias, Brian G; Ressler, Kerry J

    2014-07-16

    The centromedial amygdala (CeM), a subdivision of the central amygdala (CeA), is believed to be the main output station of the amygdala for fear expression. We provide evidence that the Tac2 gene, expressed by neurons specifically within the CeM, is required for modulating fear memories. Tac2 is colocalized with GAD65 and CaMKIIα but not with PKCd and Enk neurons in the CeM. Moreover, the Tac2 product, NkB, and its specific receptor, Nk3R, are also involved in the consolidation of fear memories. Increased Tac2 expression, through a stress-induced PTSD-like model, or following lentiviral CeA overexpression, are sufficient to enhance fear consolidation. This effect is blocked by the Nk3R antagonist osanetant. Concordantly, silencing of Tac2-expressing neurons in CeA with DREADDs impairs fear consolidation. Together, these studies further our understanding of the role of the Tac2 gene and CeM in fear processing and may provide approaches to intervention for fear-related disorders.

  17. Antipsychotic-like effect of the muscarinic acetylcholine receptor agonist BuTAC in non-human primates.

    PubMed

    Andersen, Maibritt B; Croy, Carrie Hughes; Dencker, Ditte; Werge, Thomas; Bymaster, Frank P; Felder, Christian C; Fink-Jensen, Anders

    2015-01-01

    Cholinergic, muscarinic receptor agonists exhibit functional dopamine antagonism and muscarinic receptors have been suggested as possible future targets for the treatment of schizophrenia and drug abuse. The muscarinic ligand (5R,6R)-6-(3-butylthio-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane (BuTAC) exhibits high affinity for muscarinic receptors with no or substantially less affinity for a large number of other receptors and binding sites, including the dopamine receptors and the dopamine transporter. In the present study, we wanted to examine the possible antipsychotic-like effects of BuTAC in primates. To this end, we investigated the effects of BuTAC on d-amphetamine-induced behaviour in antipsychotic-naive Cebus paella monkeys. Possible adverse events of BuTAC, were evaluated in the same monkeys as well as in monkeys sensitized to antipsychotic-induced extrapyramidal side effects. The present data suggests that, the muscarinic receptor ligand BuTAC exhibits antipsychotic-like behaviour in primates. The behavioural data of BuTAC as well as the new biochemical data further substantiate the rationale for the use of muscarinic M1/M2/M4-preferring receptor agonists as novel pharmacological tools in the treatment of schizophrenia.

  18. GEANT SIMULATIONS OF PRESHOWER CALORIMETER FOR CLAS12 UPGRADE OF THE FORWARD ELECTROMAGNETIC CALORIMETER

    SciTech Connect

    Whitlow, K.; Stepanyan, S.

    2007-01-01

    Hall B at the Thomas Jefferson National Accelerator Facility uses the CEBAF (Continuous Electron Beam Accelerator Facility) Large Acceptance Spectrometer (CLAS) to study the structure of the nucleon. An upgrade from a 6 GeV beam to a 12GeV beam is currently planned. With the beam energy upgrade, more high-energy pions will be created from the interaction of the beam and the target. Above 6GeV, the angle between the two-decay photons of high-energy pions becomes too small for the current electromagnetic calorimeter (EC) of CLAS to differentiate between two photon clusters and single photon events. Thus, a preshower calorimeter will be added in front of the EC to enable fi ner granularity and ensure better cluster separation for all CLAS experiments at higher energies. In order to optimize cost without compromising the calorimeter’s performance, three versions of the preshower, varying in number of scintillator and lead layers, were compared by their resolution and effi ciency. Using GSIM, a GEANT detector simulation program for CLAS, the passage of neutral pions and single photons through CLAS and the new preshower calorimeter (CLAS12 EC) was studied. The resolution of the CLAS12 EC was calculated from the Gaussian fi t of the sampling fraction, the energy CLAS12 EC detected over the Monte Carlo simulated energy. The single photon detection effi ciency was determined from the energy and position of the photon hits. The fractional energy resolution measured was ΔE/E = 0.0972 in the fi ve-module version, 0.111 in the four-module version, and 0.149 in the three-module version. Both the fi ve- and four-module versions had 99% single photon detection effi ciency above 0.5GeV while the 3 module version had 99% effi ciency above 1.5GeV. Based on these results, the suggested preshower confi guration is the four-module version containing twelve layers of scintillator and fi fteen layers of lead. This version provides a reasonable balance of resolution, effi ciency, and

  19. Hadron calorimeter performance with a PbWO4 EM compartment

    SciTech Connect

    Green, D.

    1996-01-01

    The CMS detector[1] at the LHC has chosen PbWO4 in order to achieve the superior photon energy resolution which is crucial in searching for the 2 photon decay of low mass Higgs bosons. The hadronic compartment is thought to be Cu absorber, since one is immersed in a 4 T magnetic field, read out by scintillator tiles coupled to wavelength shifter (WLS) fibers. The combined performance of this calorimeter is of interest in the study of jets and missing transverse energy (neutrino, SUSY signatures). For this reason, a test was made of the electromagnetic (EM) compartment combined with a reasonable approximation to the baseline HCAL ``barrel`` calorimeter. Data was taken in the H4 CERN beamline. The EM compartment was a 7 {times} 7 square array of PbWO4 crystals, which for the purposes of this study are considered as a single readout in depth (or ``compartment``) [2]. The HCAL module consisted of large scintillator plates with 24 individual longitudinal readout channels. The EM compartment was followed by 10 Cu plates each 3 cm thick, followed by 9 Cu plates each 6 cm thick. This set of absorber plates represented the HCAL compartments inside the coil. The coil itself [1] was approximated as Al and Fe plates, of a total thickness of about 1.4 absorption lengths. The coil mockup was sampled and then followed by 4 plates of 8 cm thick Cu, each with an individual readout which represented a test of the ``Tailcatcher`` concept.

  20. CALIFA, a Dedicated Calorimeter for the R{sup 3}B/FAIR

    SciTech Connect

    Cortina-Gil, D.; Alvarez-Pol, H.; Aumann, T.; Avdeichikov, V.; Bendel, M.; Benlliure, J.; Bertini, D.; Bezbakh, A.; Bloch, T.; Böhmer, M.; Borge, M.J.G.; Briz, J.A.; Cabanelas, P.; Casarejos, E.; Carmona Gallardo, M.; Cederkäll, J.; Chulkov, L.; Dierigl, M.; Di Julio, D.; Durán, I.; and others

    2014-06-15

    The R{sup 3}B experiment (Reactions with Relativistic Radioactive Beams) at FAIR (Facility for Antiproton and Ion Research) is a versatile setup dedicated to the study of reactions induced by high-energy radioactive beams. It will provide kinematically complete measurements with high efficiency, acceptance and resolution, making possible a broad physics program with rare-isotopes. CALIFA (CALorimeter for In-Flight detection of gamma-rays and high energy charged pArticles), is a complex detector based on scintillation crystals, that will surround the target of the R{sup 3}B experiment. CALIFA will act as a total absorption gamma-calorimeter and spectrometer, as well as identifier of charged particles from target residues. This versatility is its most challenging requirement, demanding a huge dynamic range, to cover from low energy gamma-rays up to 300 MeV protons. This fact, along with the high-energy of the beams determine the conceptual design of the detector, presented in this paper, together with the technical solutions proposed for its construction.

  1. Readout Electronics for BGO Calorimeter of DAMPE: Status during the First Half-year after Launching

    NASA Astrophysics Data System (ADS)

    Ma, Siyuan; Feng, Changqing; Zhang, Deliang; Wang, Qi

    2016-07-01

    The DAMPE (DArk Matter Particle Explorer) is a scientic satellite which was successfully launched into a 500 Km sun-synchronous orbit, on December 17th, 2015, from the Jiuquan Satellite Launch Center of China. The major scientific objective of DAMPE mission is indirect searching for dark matter by observing high energy primary cosmic rays, especially positrons/electrons and gamma rays with an energy range from 5 GeV to 10 TeV. The BGO (Bismuth Germanate Oxide) calorimeter, which is a critical sub-detector of DAMPE payload, was developed for measuring the energy of cosmic particles, distinguishing positrons/electrons and gamma rays from hadron background, and providing trigger information. It is composed of 308 BGO crystal logs, with the size of 2.5cm*2.5cm*60cm for each log to form a total absorption electromagnetic calorimeter. All the BGO logs are stacked in 14 layers, with each layer consisting of 22 BGO crystal logs and each log is viewed by two Hamamatsu R5610A PMTs (photomultiplier tubes), from both sides respectively. Each PMT incorporates a three dynode pick off to achieve a large dynamic range, which results in 616 PMTs and 1848 signal channels. The main function of readout electronics system, which consists of 16 FEE(Front End Electronics) modules, is to precisely measure the charge of PMT signals and providing "hit" signals. The hit signals are sent to the trigger module of PDPU (Payload Data Process Unit) to generate triggers for the payload. The calibration of the BGO calorimeter is composed of pedestal testing and electronic linear scale, which are executed frequently in the space after launching. The data of the testing is transmitted to ground station in the form of scientific data. The monitor status consists of temperature, current and status words of the FEE, which are measured and recorded every 16 seconds and packed in the engineering data, then transmitted to ground station. The status of the BGO calorimeter can be evaluated by the calibration

  2. Design and status of the Mu2e electromagnetic calorimeter

    NASA Astrophysics Data System (ADS)

    Atanov, N.; Baranov, V.; Budagov, J.; Carosi, R.; Cervelli, F.; Colao, F.; Cordelli, M.; Corradi, G.; Dané, E.; Davydov, Yu. I.; Di Falco, S.; Donati, S.; Donghia, R.; Echenard, B.; Flood, K.; Giovannella, S.; Glagolev, V.; Grancagnolo, F.; Happacher, F.; Hitlin, D. G.; Martini, M.; Miscetti, S.; Miyashita, T.; Morescalchi, L.; Murat, P.; Pasciuto, D.; Pezzullo, G.; Porter, F.; Saputi, A.; Sarra, I.; Soleti, S. R.; Spinella, F.; Tassielli, G.; Tereshchenko, V.; Usubov, Z.; Zhu, R. Y.

    2016-07-01

    The Mu2e experiment at Fermilab aims at measuring the neutrinoless conversion of a negative muon into an electron and reach a single event sensitivity of 2.5 ×10-17 after three years of data taking. The monoenergetic electron produced in the final state, is detected by a high precision tracker and a crystal calorimeter, all embedded in a large superconducting solenoid (SD) surrounded by a cosmic ray veto system. The calorimeter is complementary to the tracker, allowing an independent trigger and powerful particle identification, while seeding the track reconstruction and contributing to remove background tracks mimicking the signal. In order to match these requirements, the calorimeter should have an energy resolution of O(5)% and a time resolution better than 500 ps at 100 MeV. The baseline solution is a calorimeter composed of two disks of BaF2 crystals read by UV extended, solar blind, Avalanche Photodiode (APDs), which are under development from a JPL, Caltech, RMD consortium. In this paper, the calorimeter design, the R&D studies carried out so far and the status of engineering are described. A backup alternative setup consisting of a pure CsI crystal matrix read by UV extended Hamamatsu MPPC's is also presented.

  3. Design and status of the Mu2e electromagnetic calorimeter

    SciTech Connect

    Atanov, N.; Baranov, V.; Budagov, J.; Carosi, R.; Cervelli, F.; Colao, F.; Cordelli, M.; Corradi, G.; Dane, E.; Davydov, Yu. I.; Di Falco, S.; Donati, S.; Donghia, R.; Echenard, B.; Flood, K.; Giovannella, S.; Glagolev, V.; Grancagnolo, F.; Happacher, F.; Hitlin, D. G.; Martini, M.; Miscetti, Stefano; Miyashita, T.; Morescalchi, L.; Murat, P.; Pasciuto, D.; Pezzullo, G.; Porter, F.; Saputi, A.; Sarra, I.; Soleti, S. R.; Spinella, F.; Tassielli, G.; Tereshchenko, V.; Usubov, Z.; Zhu, R. Y.

    2015-10-02

    Here, the Mu2e experiment at Fermilab aims at measuring the neutrinoless conversion of a negative muon into an electron and reach a single event sensitivity of 2.5×10–17 after three years of data taking. The monoenergetic electron produced in the final state, is detected by a high precision tracker and a crystal calorimeter, all embedded in a large superconducting solenoid (SD) surrounded by a cosmic ray veto system. The calorimeter is complementary to the tracker, allowing an independent trigger and powerful particle identification, while seeding the track reconstruction and contributing to remove background tracks mimicking the signal. In order to match these requirements, the calorimeter should have an energy resolution of O(5)% and a time resolution better than 500 ps at 100 MeV. The baseline solution is a calorimeter composed of two disks of BaF2 crystals read by UV extended, solar blind, Avalanche Photodiode (APDs), which are under development from a JPL, Caltech, RMD consortium. In this paper, the calorimeter design, the R&D; studies carried out so far and the status of engineering are described. A backup alternative setup consisting of a pure CsI crystal matrix read by UV extended Hamamatsu MPPC's is also presented.

  4. Design and status of the Mu2e electromagnetic calorimeter

    DOE PAGES

    Atanov, N.; Baranov, V.; Budagov, J.; ...

    2015-10-02

    Here, the Mu2e experiment at Fermilab aims at measuring the neutrinoless conversion of a negative muon into an electron and reach a single event sensitivity of 2.5×10–17 after three years of data taking. The monoenergetic electron produced in the final state, is detected by a high precision tracker and a crystal calorimeter, all embedded in a large superconducting solenoid (SD) surrounded by a cosmic ray veto system. The calorimeter is complementary to the tracker, allowing an independent trigger and powerful particle identification, while seeding the track reconstruction and contributing to remove background tracks mimicking the signal. In order to matchmore » these requirements, the calorimeter should have an energy resolution of O(5)% and a time resolution better than 500 ps at 100 MeV. The baseline solution is a calorimeter composed of two disks of BaF2 crystals read by UV extended, solar blind, Avalanche Photodiode (APDs), which are under development from a JPL, Caltech, RMD consortium. In this paper, the calorimeter design, the R&D; studies carried out so far and the status of engineering are described. A backup alternative setup consisting of a pure CsI crystal matrix read by UV extended Hamamatsu MPPC's is also presented.« less

  5. Characterization of Novel Calorimeters in the Annular Core Research Reactor

    NASA Astrophysics Data System (ADS)

    Hehr, Brian D.; Parma, Edward J.; Peters, Curtis D.; Naranjo, Gerald E.; Luker, S. Michael

    2016-02-01

    A series of pulsed irradiation experiments have been performed in the central cavity of Sandia National Laboratories' Annular Core Research Reactor (ACRR) to characterize the responses of a set of elemental calorimeter materials including Si, Zr, Sn, Ta, W, and Bi. Of particular interest was the perturbing effect of the calorimeter itself on the ambient radiation field - a potential concern in dosimetry applications. By placing the calorimeter package into a neutron-thermalizing lead/polyethylene (LP) bucket and irradiating both with and without a cadmium wrapper, it was demonstrated that prompt capture gammas generated inside the calorimeters can be a significant contributor to the measured dose in the active disc region. An MCNP model of the experimental setup was shown to replicate measured dose responses to within 10%. The internal (n,γ) contribution was found to constitute as much as 50% of the response inside the LP bucket and up to 20% inside the nominal (unmodified) cavity environment, with Ta and W exhibiting the largest enhancement due to their sizable (n,γ) cross sections. Capture reactions in non-disc components of the calorimeter were estimated to be responsible for up to a few percent of the measured response. This work was supported by the United States Department of Energy under Contract DE-AC04-94AL85000. Sandia is a multiprogram laboratory operated by Sandia Corporation, a Lockheed Martin Company, for the United States Department of Energy.

  6. Simulations of a Thin Sampling Calorimeter with GEANT/FLUKA

    NASA Technical Reports Server (NTRS)

    Lee, Jeongin; Watts, John; Howell, Leonard; Rose, M. Franklin (Technical Monitor)

    2000-01-01

    The Advanced Cosmic-ray Composition Experiment for the Space Station (ACCESS) will investigate the origin, composition and acceleration mechanism of cosmic rays by measuring the elemental composition of the cosmic rays up to 10(exp 15) eV. These measurements will be made with a thin ionization calorimeter and a transition radiation detector. This paper reports studies of a thin sampling calorimeter concept for the ACCESS thin ionization calorimeter. For the past year, a Monte Carlo simulation study of a Thin Sampling Calorimeter (TSC) design has been conducted to predict the detector performance and to design the system for achieving the ACCESS scientific objectives. Simulation results show that the detector energy resolution function resembles a Gaussian distribution and the energy resolution of TSC is about 40%. In addition, simulations of the detector's response to an assumed broken power law cosmic ray spectra in the region where the 'knee' of the cosmic ray spectrum occurs have been conducted and clearly show that a thin sampling calorimeter can provide sufficiently accurate estimates of the spectral parameters to meet the science requirements of ACCESS. n

  7. I-TAC is a dominant chemokine in controlling skin intragraft inflammation via recruiting CXCR3+ cells into the graft.

    PubMed

    Li, Baohua; Xu, Wei; Xu, Lin; Jiang, Zhenggang; Wen, Zhenke; Li, Kang; Xiong, Sidong

    2010-01-01

    Chemokines play a critical role in the acute transplant rejection. In order to provide an overview of the chemokine expression during the course of acute allograft rejection, the intragraft expression profile of 11 chemokines representative of all four chemokine subfamilies was analyzed in a murine skin transplantation model of acute rejection. It was found that RANTES/CCL5, TARC/CCL17 and FKN/CX(3)CL1 were expressed at equivalent levels in iso- and allografts. However, the other eight chemokines expression was up-regulated to some extent in allograft compared with that in isograft. The levels of MIP-1alpha/CCL3, MIP-3alpha/CCL20 and CTACK/CCL27 were progressively increased from early stage (day 3 post-transplantation) to late stage (day 11). Mig/CXCL9, IP-10/CXCL10, I-TAC/CXCL11, CXCL16 and LTN/XCL1 expression was elevated at middle stage (day 7), and peaked at late stage. Among the up-regulated chemokines, I-TAC was the most obviously elevated chemokine. Therefore, the effect of I-TAC on the skin acute allograft rejection was evaluated. Block of I-TAC by the intradermal injection of anti-I-TAC monoclonal antibody (mAb) reduced the number of CXCR3(+) cells in skin allograft and significantly prolonged the skin allograft survival. The mAb treatment did not influence the proliferation of the intragraft infiltrating cells in response to the allogeneic antigens, but significantly decreased the number of the infiltrating cells and consequently lowered the secretion of IFN-gamma and TNF-alpha. These data indicate I-TAC might be a dominant chemokine involved in the intradermal infiltration and I-TAC-targeted intervening strategies would have potential application for the alleviation of acute transplant rejection.

  8. Trypanosomal TAC40 constitutes a novel subclass of mitochondrial β-barrel proteins specialized in mitochondrial genome inheritance.

    PubMed

    Schnarwiler, Felix; Niemann, Moritz; Doiron, Nicholas; Harsman, Anke; Käser, Sandro; Mani, Jan; Chanfon, Astrid; Dewar, Caroline E; Oeljeklaus, Silke; Jackson, Christopher B; Pusnik, Mascha; Schmidt, Oliver; Meisinger, Chris; Hiller, Sebastian; Warscheid, Bettina; Schnaufer, Achim C; Ochsenreiter, Torsten; Schneider, André

    2014-05-27

    Mitochondria cannot form de novo but require mechanisms allowing their inheritance to daughter cells. In contrast to most other eukaryotes Trypanosoma brucei has a single mitochondrion whose single-unit genome is physically connected to the flagellum. Here we identify a β-barrel mitochondrial outer membrane protein, termed tripartite attachment complex 40 (TAC40), that localizes to this connection. TAC40 is essential for mitochondrial DNA inheritance and belongs to the mitochondrial porin protein family. However, it is not specifically related to any of the three subclasses of mitochondrial porins represented by the metabolite transporter voltage-dependent anion channel (VDAC), the protein translocator of the outer membrane 40 (TOM40), or the fungi-specific MDM10, a component of the endoplasmic reticulum-mitochondria encounter structure (ERMES). MDM10 and TAC40 mediate cellular architecture and participate in transmembrane complexes that are essential for mitochondrial DNA inheritance. In yeast MDM10, in the context of the ERMES, is postulated to connect the mitochondrial genomes to actin filaments, whereas in trypanosomes TAC40 mediates the linkage of the mitochondrial DNA to the basal body of the flagellum. However, TAC40 does not colocalize with trypanosomal orthologs of ERMES components and, unlike MDM10, it regulates neither mitochondrial morphology nor the assembly of the protein translocase. TAC40 therefore defines a novel subclass of mitochondrial porins that is distinct from VDAC, TOM40, and MDM10. However, whereas the architecture of the TAC40-containing complex in trypanosomes and the MDM10-containing ERMES in yeast is very different, both are organized around a β-barrel protein of the mitochondrial porin family that mediates a DNA-cytoskeleton linkage that is essential for mitochondrial DNA inheritance.

  9. Trypanosomal TAC40 constitutes a novel subclass of mitochondrial β-barrel proteins specialized in mitochondrial genome inheritance

    PubMed Central

    Schnarwiler, Felix; Niemann, Moritz; Doiron, Nicholas; Harsman, Anke; Käser, Sandro; Mani, Jan; Chanfon, Astrid; Dewar, Caroline E.; Oeljeklaus, Silke; Jackson, Christopher B.; Pusnik, Mascha; Schmidt, Oliver; Meisinger, Chris; Hiller, Sebastian; Warscheid, Bettina; Schnaufer, Achim C.; Ochsenreiter, Torsten; Schneider, André

    2014-01-01

    Mitochondria cannot form de novo but require mechanisms allowing their inheritance to daughter cells. In contrast to most other eukaryotes Trypanosoma brucei has a single mitochondrion whose single-unit genome is physically connected to the flagellum. Here we identify a β-barrel mitochondrial outer membrane protein, termed tripartite attachment complex 40 (TAC40), that localizes to this connection. TAC40 is essential for mitochondrial DNA inheritance and belongs to the mitochondrial porin protein family. However, it is not specifically related to any of the three subclasses of mitochondrial porins represented by the metabolite transporter voltage-dependent anion channel (VDAC), the protein translocator of the outer membrane 40 (TOM40), or the fungi-specific MDM10, a component of the endoplasmic reticulum–mitochondria encounter structure (ERMES). MDM10 and TAC40 mediate cellular architecture and participate in transmembrane complexes that are essential for mitochondrial DNA inheritance. In yeast MDM10, in the context of the ERMES, is postulated to connect the mitochondrial genomes to actin filaments, whereas in trypanosomes TAC40 mediates the linkage of the mitochondrial DNA to the basal body of the flagellum. However, TAC40 does not colocalize with trypanosomal orthologs of ERMES components and, unlike MDM10, it regulates neither mitochondrial morphology nor the assembly of the protein translocase. TAC40 therefore defines a novel subclass of mitochondrial porins that is distinct from VDAC, TOM40, and MDM10. However, whereas the architecture of the TAC40-containing complex in trypanosomes and the MDM10-containing ERMES in yeast is very different, both are organized around a β-barrel protein of the mitochondrial porin family that mediates a DNA–cytoskeleton linkage that is essential for mitochondrial DNA inheritance. PMID:24821793

  10. TaC as a diffusion barrier between Si and Cu

    NASA Astrophysics Data System (ADS)

    Laurila, Tomi; Zeng, Kejun; Kivilahti, Jorma K.; Molarius, Jyrki; Suni, Iikka

    2002-04-01

    The reaction mechanisms and related microstructures in the Si/TaC/Cu metallization system have been studied experimentally and theoretically by utilizing ternary Si-Ta-C and Ta-C-Cu phase diagrams as well as activity diagrams calculated at 800 °C. With the help of sheet resistance measurements, Rutherford backscattering spectrometry, x-ray diffraction, scanning electron microscopy, and transmission electron microscopy, the metallization structure with the 70 nm thick TaC barrier layer was observed to fail completely at temperatures above 725 °C because of the formation of large Cu3Si protrusions. However, the formation of amorphous Ta layer containing significant amounts of carbon and oxygen was already observed at the TaC/Cu interface at 600 °C. This layer also constituted an additional barrier layer for Cu diffusion, which occurred only after the crystallization of the amorphous layer. The formation of Ta2O5 was observed at 725 °C with x-ray diffraction, indicating that the oxygen rich amorphous layer had started to crystallize. The formation of SiC and TaSi2 occurred almost simultaneously at 800 °C. The observed reaction structure was consistent with the thermodynamics of the ternary system. The metallization structures with 7 nm and 35 nm TaC barrier layers failed above 550 °C and 650 °C, respectively, similarly because of the formation of Cu3Si. The high formation temperature of TaSi2 and SiC implies high stability of Si/TaC interface, thus making TaC layer a potential candidate to be used as a diffusion barrier for Cu metallization.

  11. Resonant two-photon ionization spectroscopy of jet-cooled tantalum carbide, TaC.

    PubMed

    Krechkivska, Olha; Morse, Michael D

    2010-08-07

    The optical spectrum of diatomic TaC has been investigated for the first time, with transitions recorded in the range from 17,850 to 20,000 cm(-1). Six bands were rotationally resolved and analyzed to obtain ground and excited state parameters, including band origins, upper and lower state rotational constants and bond lengths, Fermi contact parameter b(F) for the ground state, and lambda doubling parameters for the excited states. The ground state of TaC was found to be X (2)Sigma(+), originating from the 1sigma(2)2sigma(2)1pi(4)3sigma(1) electronic configuration, in which only the valence orbitals arising from the Ta(5d+6s) and C(2s+2p) orbitals are listed. All of the rotationally resolved and analyzed bands were found to originate from the ground state, giving B(0)"=0.489 683(83) cm(-1), r(0)"=1.749 01(15) A, and b(F)"=0.131 20(36) cm(-1) (1sigma error limits) for (181)Ta (12)C. Comparison of the Fermi contact parameter to the atomic value shows that the 3sigma orbital is approximately 75% Ta 6s in character. The other group 5 transition metal carbides, VC and NbC, have long been known to have 1sigma(2)2sigma(2)1pi(4)1delta(1), (2)Delta ground states, with low-lying 1sigma(2)2sigma(2)1pi(4)3sigma(1), (2)Sigma(+) excited states. The emergence of a different ground state in TaC, as compared to VC and NbC, is due to the relativistic stabilization of the 6s orbital in Ta. This lowers the energy of the 6s-like 3sigma orbital in TaC, causing the 1sigma(2)2sigma(2)1pi(4)3sigma(1), (2)Sigma(+) state to fall below the 1sigma(2)2sigma(2)1pi(4)1delta(1), (2)Delta state.

  12. A compact light readout system for longitudinally segmented shashlik calorimeters

    NASA Astrophysics Data System (ADS)

    Berra, A.; Brizzolari, C.; Cecchini, S.; Cindolo, F.; Jollet, C.; Longhin, A.; Ludovici, L.; Mandrioli, G.; Mauri, N.; Meregaglia, A.; Paoloni, A.; Pasqualini, L.; Patrizii, L.; Pozzato, M.; Pupilli, F.; Prest, M.; Sirri, G.; Terranova, F.; Vallazza, E.; Votano, L.

    2016-09-01

    The longitudinal segmentation of shashlik calorimeters is challenged by dead zones and non-uniformities introduced by the light collection and readout system. This limitation can be overcome by direct fiber-photosensor coupling, avoiding routing and bundling of the wavelength shifter fibers and embedding ultra-compact photosensors (SiPMs) in the bulk of the calorimeter. We present the first experimental test of this readout scheme performed at the CERN PS-T9 beamline in 2015 with negative particles in the 1-5 GeV energy range. In this paper, we demonstrate that the scheme does not compromise the energy resolution and linearity compared with standard light collection and readout systems. In addition, we study the performance of the calorimeter for partially contained charged hadrons to assess the e / π separation capability and the response of the photosensors to direct ionization.

  13. Highly granular hadron calorimeter: software compensation and shower decomposition

    NASA Astrophysics Data System (ADS)

    Chadeeva, M.; CALICE Collaboration

    2016-02-01

    The highly granular analogue hadron calorimeter was developed and constructed by the CALICE collaboration. The active layers of the calorimeter are assembled from scintillator tiles with individual readout by silicon photomultipliers and are interleaved with absorber plates. The response and resolution of the calorimeter equipped with steel absorber was intensively tested in single particle beams. The application of software compensation techniques developed for the scintillator-steel prototype allows for reduction of the stochastic term of the single particle resolution from 58%/ √E/GeV to 45%/ √E/GeV. The detailed study and decomposition of the longitudinal and radial profiles of hadron-induced showers in the energy range from 10 to 80 GeV are presented and compared to GEANT4 simulations.

  14. Calibration and monitoring systems of the ATLAS tile hadron calorimeter

    NASA Astrophysics Data System (ADS)

    Boumediene, D.

    2013-08-01

    The TileCal is the hadronic calorimeter covering the most central region of the ATLAS experiment at LHC. It is a sampling calorimeter with iron plates as absorber and plastic scintillating tiles as the active material. The scintillation light produced by the passage of charged particles is transmitted by wavelength shifting fibers to about 10,000 photomultiplier tubes (PMTs). Integrated to the calorimeter, there is a composite device that allows to monitor and/or equalize the signals at various stages of their formation. This device is based on signal generation from different sources: radioactive, LASER, charge injection and minimum bias events produced in proton-proton collisions. Recent performances of these systems are presented.

  15. CMS Hadron Endcap Calorimeter Upgrade Studies for Super-LHC

    NASA Astrophysics Data System (ADS)

    Bilki, Burak; CMS HCAL Collaboration

    2011-04-01

    When the Large Hadron Collider approaches Super-LHC conditions above a luminosity of 1034cm-2s-1, the scintillator tiles of the CMS Hadron Endcap calorimeters will lose their efficiencies. As a radiation hard solution, the scintillator tiles are planned to be replaced by quartz plates. In order to improve the efficiency of the photodetection, various methods were investigated including radiation hard wavelength shifters, p-terphenyl or 4% gallium doped zinc oxide. We constructed a 20 layer calorimeter prototype with pTp coated plates of size 20 cm × 20 cm, and tested the hadronic and the electromagnetic capabilities at the CERN H2 beam-line. The beam tests revealed a substantial light collection increase with pTp or ZnO:Ga deposited quartz plates. Here we report on the current R&D for a viable endcap calorimeter solution for CMS with beam tests and radiation damage studies.

  16. Performance of the DELPHI small angle tile calorimeter

    SciTech Connect

    Alvsvaag, S.J.; Maeland, O.A.; Klovning, A.

    1996-06-01

    The DELPHI STIC detector is a lead-scintillator sampling calorimeter with wave length shifting optical fibers used for light collection. The main goal of the calorimeter at LEP100 is to measure the luminosity with an accuracy better than 0.1%. The detector has been in operation since the 1994 LEP run. Presented here is the performance measured during the 1994--1995 LEP runs, with the emphasis on the achieved energy and space resolution, the long-term stability and the efficiency of the detector. The new bunchtrains mode of LEP requires a rather sophisticated trigger and timing scheme which is also presented. To control the trigger efficiency and stability of the calorimeter channels, a LED-based monitoring system has been developed.

  17. The lead-glass electromagnetic calorimeter for the SELEX experiment

    SciTech Connect

    M. Y. Balatz et al.

    2004-07-19

    A large-acceptance, highly segmented electromagnetic lead glass calorimeter for Experiment E781 (SELEX) at Fermi National Acceleration Laboratory was designed and built. This detector has been used to reconstruct photons and electrons with energies ranging from few GeV up to 500 GeV in the collisions of the 650 GeV {Sigma}{sup -} hyperons and {pi}{sup -} mesons with the target nucleons. The design, calibration and performance of the calorimeter are described. Energy resolution and position resolution are assessed using both calibration electron beams and {pi}{sup 0} mesons reconstructed in 650 GeV hadron-hadron interactions. The performance of the calorimeter in selecting resonant states that involve photons is demonstrated.

  18. The NA62 liquid Krypton calorimeter's new readout system

    NASA Astrophysics Data System (ADS)

    Ceccucci, A.; Fantechi, R.; Farthouat, P.; Lamanna, G.; Rouet, J.; Ryjov, V.; Venditti, S.

    2014-01-01

    The NA62 experiment [1] at CERN SPS (Super Proton Synchrotron) accelerator aims at studying Kaon decays with high precision. The high resolution Liquid Krypton (LKr) calorimeter, built for the NA48 [2] experiment, is a crucial part of the experiment photon-veto system; to cope with the new requirements, the back-end electronics of the LKr had to be completely renewed. Due to the huge number of the calorimeter readout channels ( ~ 14 K) and the maintenance requirement over 10 years of the experiment lifetime, the decision to sub-contract the development and production to industry was taken in 2011. This paper presents the primary test results of the Calorimeter REAdout Module (CREAM) [3] prototype delivered by the manufacturer in March 2013. All essential features, analog performance, data processing and readout, are covered.

  19. Development of Metallic Magnetic Calorimeters for Nuclear Safeguards Applications

    SciTech Connect

    Bates, Cameron Russell

    2015-03-11

    Many nuclear safeguards applications could benefit from high-resolution gamma-ray spectroscopy achievable with metallic magnetic calorimeters. This dissertation covers the development of a system for these applications based on gamma-ray detectors developed at the University of Heidelberg. It demonstrates new calorimeters of this type, which achieved an energy resolution of 45.5 eV full-width at half-maximum at 59.54 keV, roughly ten times better than current state of the art high purity germanium detectors. This is the best energy resolution achieved with a gamma-ray metallic magnetic calorimeter at this energy to date. In addition to demonstrating a new benchmark in energy resolution, an experimental system for measuring samples with metallic magnetic calorimeters was constructed at Lawrence Livermore National Laboratory. This system achieved an energy resolution of 91.3 eV full-width at half-maximum at 59.54 keV under optimal conditions. Using this system it was possible to characterize the linearity of the response, the count-rate limitations, and the energy resolution as a function of temperature of the new calorimeter. With this characterization it was determined that it would be feasible to measure 242Pu in a mixed isotope plutonium sample. A measurement of a mixed isotope plutonium sample was performed over the course of 12 days with a single two-pixel metallic magnetic calorimeter. The relative concentration of 242Pu in comparison to other plutonium isotopes was determined by direct measurement to less than half a percent accuracy. This is comparable with the accuracy of the best-case scenario using traditional indirect methods. The ability to directly measure the relative concentration of 242Pu in a sample could enable more accurate accounting and detection of indications of undeclared activities in nuclear safeguards, a better constraint on source material in forensic samples containing plutonium, and improvements in verification in a future plutonium

  20. The influence of theta transcranial alternating current stimulation (tACS) on working memory storage and processing functions.

    PubMed

    Jaušovec, Norbert; Jaušovec, Ksenija; Pahor, Anja

    2014-02-01

    The study aimed to explore the role of the fronto-parietal brain network in working memory function--in temporary storage and manipulation of information. In a single blind sham controlled experiment 36 respondents solved different working memory tasks after theta transcranial alternating current stimulation (tACS) was applied to left frontal, left parietal and right parietal areas. Both verum tACS protocols stimulating parietal brain areas (target electrodes positioned at location P3, or P4) had a positive effect on WM storage capacity as compared with sham tACS, whereas no such influence was observed for the stimulation of the left frontal area (target electrode positioned at location F3). A second finding was that left parietal theta tACS had a more pronounced influence on backward recall than on forward recall, which was not related to task content (spatial or verbal). The influence of theta tACS on WM executive processes was most pronounced for right parietal stimulation. The results are discussed in the broad theoretical framework of the multicomponent model of working memory.

  1. Phase I study of TAC-101, an oral synthetic retinoid, in Japanese patients with advanced hepatocellular carcinoma.

    PubMed

    Okusaka, Takuji; Ueno, Hideki; Ikeda, Masafumi; Takezako, Yoriko; Morizane, Chigusa

    2012-08-01

    Preclinical models have shown that TAC-101 (4-[3,5-bis(trimethylsilyl) benzamide] benzoic acid), an oral synthetic retinoid, has antitumor activity in hepatocellular carcinoma (HCC). We conducted a phase I study in Japanese patients with advanced HCC to examine the pharmacokinetics, recommended dose, safety, and efficacy of TAC-101. The administered dose of TAC-101 was 10 mg/day in four patients (level 1), 20 mg/day in six (level 2), and 30 mg/day in three (level 3). There was no dose-limiting toxicity at level 1. Only one patient each had dose-limiting toxicity at level 2 (grade 2 fatigue, recovery requiring eight or more consecutive days of rest) and at level 3 (grade 3 splenic vein thrombosis). Level 3 (30 mg/day) was considered the maximum tolerated dose and 20 mg/day the recommended dose by a panel of medical experts, placing maximum emphasis on safety. The most frequent adverse events were fatigue, headache, and dermal symptoms such as rash. Pharmacokinetic parameters in Japanese patients with HCC were similar to those in patients in the United States, most of whom were Caucasian. Although no patient had a complete or partial response, the disease control rate was 38.5%. In conclusion, the recommended dose of TAC-101 for patients with HCC is 20 mg/day. TAC-101 had an acceptable toxicity profile, warranting further evaluation in clinical trials.

  2. Improvements in a calorimeter for high-power CW lasers

    NASA Technical Reports Server (NTRS)

    Chamberlain, G. E.; Simpson, P. A.; Smith, R. L.

    1978-01-01

    A technique for improving the measurement certainty with the BB series (Smith et al., 1972) of electrically calibrated calorimeters used in high-energy lasers is described. The technique is based on monitoring the energy which is backscattered from the meter and monitoring the overspill radiation impinging on the calorimeter at the entrance aperture. The design and performance of a second generation BB meter is discussed and compared to that of the original device in terms of number of electrical calibrations, the residual standard deviation of electrical calibration, the calibration constant for laser energy, the correcting factor for systematics, inaccuracy, imprecision, and uncertainty.

  3. The Scintillating Optical Fiber Calorimeter Instrument Performance (SOFCAL)

    NASA Technical Reports Server (NTRS)

    Christl, M. J.; Benson, C. M.; Berry, F. A.; Fountain, W. F.; Gregory, J. C.; Johnson, J. S.; Munroe, R. B.; Parnell, T. A.; Takahashi, Y.; Watts, J. W.

    1999-01-01

    SOFCAL is a balloon-borne instrument designed to measure the P-He cosmic ray spectra from about 200 GeV/amu - 20 TeV/amu. SOFCAL uses a thin lead and scintillating-fiber ionization calorimeter to measure the cascades produced by cosmic rays interacting in the hybrid detector system. Above the fiber calorimeter is an emulsion chamber that provides the interaction target, primary particle identification and in-flight energy calibration for the scintillating fiber data. The energy measurement technique and its calibration are described, and the present results from the analysis of a 1 day balloon flight will be presented.

  4. Design and Prototyping of a High Granularity Scintillator Calorimeter

    SciTech Connect

    Zutshi, Vishnu

    2016-03-27

    A novel approach for constructing fine-granularity scintillator calorimeters, based on the concept of an Integrated Readout Layer (IRL) was developed. The IRL consists of a printed circuit board inside the detector which supports the directly-coupled scintillator tiles, connects to the surface-mount SiPMs and carries the necessary front-end electronics and signal/bias traces. Prototype IRLs using this concept were designed, prototyped and successfully exposed to test beams. Concepts and implementations of an IRL carried out with funds associated with this contract promise to result in the next generation of scintillator calorimeters.

  5. Phase 1 upgrade of the CMS forward hadronic calorimeter

    NASA Astrophysics Data System (ADS)

    Noonan, D.

    2017-02-01

    The CMS experiment at the Large Hadron Collider at CERN is upgrading the photo-detection and readout system of the forward hadronic calorimeter. The phase 1 upgrade of the CMS forward calorimeter requires the replacement of the current photomultiplier tubes, as well as the installation of a new front-end readout system. The new photomultiplier tubes contain a thinner window as well as multi-anode readout. The front-end electronics will use the QIE10 ASIC which combines signal digitization with timing information. The major components of the upgrade as well as the current status are described in this paper.

  6. Field test of the bulk-assay calorimeter

    SciTech Connect

    Perry, R.B.; Keddar, A.

    1982-10-01

    The Bulk-Assay Calorimeter described in ANL-NDA-9/ISPO-14 was field tested at the Belgonucleaire mixed-oxide fuel fabrication plant at Dessel, Belgium, May 13-19, 1982. This instrument was developed under ISPO Tasks A-9 and A-47 at Argonne National Laboratory and was supplied to the IAEA through the U.S support program. Five containers of plutonium-oxide feed stock used in the manufacture of mixed-oxide LMFBR-type fuel were assayed during the test. Electrical measurements to verify the calibration of the calorimeter were also made.

  7. Radiation damage studies for the SDC electromagnetic calorimeter

    NASA Astrophysics Data System (ADS)

    Fazely, A. R.; Gunasingha, R.; Imlay, R. L.; Khosravi, E. S.; Lim, Jit-Ning; Lyndon, C.; McMills, G.; McNeil, R. R.; Metcalf, W. J.; Courtney, J. C.; Tashakkori, R.; Vegara, B. J.

    1993-01-01

    We report the results from a year long study aimed at radiation resistance and optical performance of scintillator tile with green wave shifter fiber readout. A careful investigation of several rad-hard plastic scintillators from Bicron and Kuraray, studies indicate that for a specific rad-hard Bicron scintillator, it is possible to build a tile/fiber EM calorimeter that can operate in the design luminosity of SSC. This calorimeter with excellent optical response would only have a light loss of about 5% after being exposed to 1 Mrad.

  8. The Electromagnetic Calorimeter of the future PANDA Detector

    SciTech Connect

    Novotny, Rainer

    2006-10-27

    Experiments with a cooled antiproton beam at the future accelerator facility FAIR at GSI, Darmstadt, will be performed with the 4{pi} detector PANDA comprising a high resolution, compact and fast homogeneous electromagnetic calorimeter to detect photons between 10MeV and 10GeV energy inside a superconducting solenoid (2T). The target calorimeter comprises more than 20,000 PbWO4 crystals of significantly enhanced quality read-out with large area avalanche photodiodes at an operating temperature of -25 degree sign C. The paper describes the quality of PWO-II and illustrates the future performance based on response measurements with high-energy photons.

  9. The upgrade of the ATLAS first-level calorimeter trigger

    NASA Astrophysics Data System (ADS)

    Yamamoto, Shimpei

    2016-07-01

    The first-level calorimeter trigger (L1Calo) had operated successfully through the first data taking phase of the ATLAS experiment at the CERN Large Hadron Collider. Towards forthcoming LHC runs, a series of upgrades is planned for L1Calo to face new challenges posed by the upcoming increases of the beam energy and the luminosity. This paper reviews the ATLAS L1Calo trigger upgrade project that introduces new architectures for the liquid-argon calorimeter trigger readout and the L1Calo trigger processing system.

  10. A purity monitor for the KEDR liquid krypton calorimeter

    SciTech Connect

    Evtushenko, P. N.; Kotov, K. Yu.; Maslennikov, A. L.; Peleganchuk, S. V.; Snopkov, R. G.; Rogozin, A. I.; Tikhonov, Yu. A.

    2016-06-01

    We present a purity monitor for the KEDR liquid krypton calorimeter. A new method is suggested based on the usage of a short pulse of a gas discharge as a source of ultraviolet radiation for the photoproduction of electrons in a drift cell of the monitor. This paper describes the design of the monitor, the results of experiments with gaseous and liquid krypton, as well as the experience of using the developed device in the process of krypton purification for the KEDR liquid krypton calorimeter.

  11. Metabolism of Tac (IL2Ralpha): physiology of cell surface shedding and renal catabolism, and suppression of catabolism by antibody binding

    PubMed Central

    1996-01-01

    The interleukin 2 receptor alpha (IL2Ralpha; CD25; Tac) is the prototypic model for soluble receptor studies. It exists in vivo as a transmembrane complete molecule (TM-Tac) on cell surfaces and as a truncated soluble form (sTac; sIL2R alpha). sTac has been used as a serum marker of T cell activation in immune disorders and of tumor burden in Tac-expressing malignancies. In vivo, serum levels of all soluble proteins depend on the balance between production and catabolism, but little is known about the metabolic features of this class of molecules. We have developed a model for Tac metabolism that incorporates new insights in its production and catabolism. Tac was shed from the surface of malignant and activated human T cells with a model half-life (t1/2) of 2-6h, but which was prolonged under certain circumstances. The rate of shedding is first order overall and nonsaturable over a two order of magnitude range of substrate (TM-Tac) expression. Once shed from cells Tac is subject to catabolic activities in the host. In vivo studies in mice showed that 90% of Tac was catabolized by the kidney with a t1/2 of 1 h and a filtration fraction of 0.11 relative to creatinine. The remaining 10% of catabolism was mediated by other tissues with a t1/2 of 10 h. Approximately 1-3% of sTac is excreted intact as proteinuria with the remaining 97-99% catabolized to amino acids. Antibody to the receptor induced a marked delay in sTac catabolism by preventing filtration of the smaller protein through the renal glomerulus and additionally suppressing other nonrenal catabolic mechanisms. A discrepancy between the catabolic rats for Tac and anti-Tac in the same complex was interpreted as a previously unrecognized differential catabolic mechanism, suggesting features of the Brambell hypothesis and immunoglobulin G transport and catabolism, in which the antigen-in-complex in intracellular vesicles is relatively less protected from catabolism than the associated antibody. In light of the

  12. Deuterium retention in TiC and TaC doped tungsten at high temperatures

    NASA Astrophysics Data System (ADS)

    Zibrov, M.; Mayer, M.; Gao, L.; Elgeti, S.; Kurishita, H.; Gasparyan, Yu.; Pisarev, A.

    2015-08-01

    Samples made of tungsten doped either with titanium carbide (W-1.1TiC) or tantalum carbide (W-3.3TaC) were either exposed to D2 gas at a pressure of 100 kPa at 800-963 K or irradiated by 38 eV/D ions at 800 K. The deuterium (D) inventory in the samples was examined by nuclear reaction analysis and thermal desorption spectroscopy. The D bulk concentration and total retention in W-3.3TaC were comparable in all cases to that in pure polycrystalline W. The D bulk concentration in W-1.1TiC was more than one order of magnitude higher than that in pure W after exposure to D2 gas, and was also several times higher than that in W-1.1TiC after irradiation at 800 K. It is suggested that D trapping inside the carbide precipitates in W-1.1TiC becomes essential at high temperatures.

  13. Nanodiamond embedded ta-C composite film by pulsed filtered vacuum arc deposition from a single target

    NASA Astrophysics Data System (ADS)

    Iyer, Ajai; Etula, Jarkko; Ge, Yanling; Liu, Xuwen; Koskinen, Jari

    2016-11-01

    Detonation Nanodiamonds (DNDs) are known to have sp3 core, sp2 shell, small size (few nm) and are gaining importance as multi-functional nanoparticles. Diverse methods have been used to form composites, containing detonation nanodiamonds (DNDs) embedded in conductive and dielectric matrices for various applications. Here we show a method, wherein DND-ta-C composite film, consisting of DNDs embedded in ta-C matrix have been co-deposited from the same cathode by pulsed filtered cathodic vacuum arc method. Transmission Electron Microscope analysis of these films revel the presence of DNDs embedded in the matrix of amorphous carbon. Raman spectroscopy indicates that the presence of DNDs does not adversely affect the sp3 content of DND-ta-C composite film compared to ta-C film of same thickness. Nanoindentation and nanowear tests indicate that DND-ta-C composite films possess improved mechanical properties in comparison to ta-C films of similar thickness.

  14. The muscarinic acetylcholine receptor agonist BuTAC mediates antipsychotic-like effects via the M4 subtype.

    PubMed

    Watt, Marla L; Rorick-Kehn, Linda; Shaw, David B; Knitowski, Karen M; Quets, Anne T; Chesterfield, Amy K; McKinzie, David L; Felder, Christian C

    2013-12-01

    The generation of muscarinic acetylcholine receptor (mAChR) subtype-selective compounds has been challenging, requiring use of nonpharmacological approaches, such as genetically engineered animals, to deepen our understanding of the potential that members of the muscarinic receptor subtype family hold as therapeutic drug targets. The muscarinic receptor agonist 'BuTAC' was previously shown to exhibit efficacy in animal models of psychosis, although the particular receptor subtype(s) responsible for such activity was unclear. Here, we evaluate the in vitro functional agonist and antagonist activity of BuTAC using an assay that provides a direct measure of G protein activation. In addition, we employ the conditioned avoidance response paradigm, an in vivo model predictive of antipsychotic activity, and mouse genetic deletion models to investigate which presynaptic mAChR subtype mediates the antipsychotic-like effects of BuTAC. Our results show that, in vitro, BuTAC acts as a full agonist at the M2AChR and a partial agonist at the M1 and M4 receptors, with full antagonist activity at M3- and M5AChRs. In the mouse conditioned avoidance response (CAR) assay, BuTAC exhibits an atypical antipsychotic-like profile by selectively decreasing avoidance responses at doses that do not induce escape failures. CAR results using M2(-/-), M4(-/-), and M2/M4 (M2/M4(-/-)) mice found that the effects of BuTAC were near completely lost in M2/M4(-/-) double-knockout mice and potency of BuTAC was right-shifted in M4(-/-) as compared with wild-type and M2(-/-) mice. The M2/M4(-/-) mice showed no altered sensitivity to the antipsychotic effects of either haloperidol or clozapine, suggesting that these compounds mediate their actions in CAR via a non-mAChR-mediated mechanism. These data support a role for the M4AChR subtype in mediating the antipsychotic-like activity of BuTAC and implicate M4AChR agonism as a potential novel therapeutic mechanism for ameliorating symptoms associated with

  15. The pad readout electronics of the SLD Warm Iron Calorimeter

    SciTech Connect

    Burrows, P.N.; Busza, W.; Cartwright, S.L.; Friedman, J.I.; Fuess, S.; Gonzalez, S.; Hansl-Kozanecka, T.; Kendall, H.W.; Lath, A.; Lyons, T.; Osborne, L.S.; Rosenson, L.; Schneekloth, U.; Taylor, F.E.; Verdier, R.; Wadsworth, B.; Williams, D.C.; Yamartino, J.M. ); Byers, B.L.; Escalera, J.; Gioumousis, A.; Gray, R.; Horelick, D.; Kharakh, D.; Messner, R.L.; Moss, J.; Zdark

    1990-08-01

    The design of the pad readout electronics of the Warm Iron Calorimeter for the SLD detector at SLAC, consisting of about 9000 analog channels, is described. Results of various tests performed during the construction, installation and commissioning of the electronics mounted on the detector are presented. 10 refs., 12 figs.

  16. Development of shashlik electromagnetic calorimeter prototype for SoLID

    NASA Astrophysics Data System (ADS)

    Shen, C.; Wang, Y.; Xiao, D.; Han, D.; Zou, Z.; Li, Y.; Zheng, X.; Chen, J.

    2017-03-01

    A shashlik electromagnetic calorimeter will be produced in Hall A of Jefferson Laboratory for Solenoidal large Intensity Device (SoLID) to measure the energy deposition of electrons and hadrons, and to provide particle identification after the energy of the accelerator was upgraded to 12 GeV. Tsinghua University is the member of Hall A collaboration in charge of development and production of the large shashlik electromagnetic calorimeter of SoLID. One module of that calorimeter is composed by 194 layers. Each layer consists of a 1.5 mm thick plastic scintillator put on top of a 0.5 mm thick lead plate. Scintillation light is read out by wave-length shifter fibers penetrating through the calorimeter modules longitudinally along the direction of flight of the impact particle. This paper describes the design and construction of that module, as well as a few optimization studies meant to improve its performance. A detailed Geant4 simulation also shows that an energy resolution of 5%/√ E (GeV) and a good containment for electromagnetic showers can be achieved, as well as some basic electron identification. A prototype of that module will be tested soon with an electron beam at JLab.

  17. Electromagnetic calorimeter for the HADES@FAIR experiment

    NASA Astrophysics Data System (ADS)

    Svoboda, O.; Blume, C.; Czyžycki, W.; Epple, E.; Fabbietti, L.; Galatyuk, T.; Golubeva, M.; Guber, F.; Hlaváč, S.; Ivashkin, A.; Kajetanowic, M.; Kardan, B.; Koenig, W.; Kugler, A.; Lapidus, K.; Lisowski, E.; Pietraszko, J.; Reshetin, A.; Rost, A.; Salabura, P.; Sobolev, Y. G.; Tlusty, P.; Traxler, M.

    2014-05-01

    An electromagnetic calorimeter (ECAL) is being developed to complement the dilepton spectrometer HADES currently operating on the beam of the SIS18 heavy-ion synchrotron at GSI Helmholtzzentrum für Schwerionenforschung, Darmstadt, Germany. The ECAL will allow the HADES@FAIR experiment to measure data on neutral meson production in heavy ion collisions in the energy range of 2-10 AGeV with the beam of the future accelerator SIS100@FAIR. The calorimeter will also improve the electron-hadron separation of the spectrometer, and will be used for the detection of photons from strange resonances in elementary and heavy ion reactions as well. The calorimeter will consist of 978 modules divided into 6 sectors, and it will cover forward angles of 16° < Θ < 45° and almost full azimuthal angle. Each module consists of a lead glass Cherenkov counter, photomultiplier, HV divider and an optical fiber. A dedicated LED based system being developed to monitor the stability of the calorimeter is discussed. Various prototypes of front-end electronics are presented and the achieved energy and time resolution determined using pulses from a pulse generator and a real detector signal induced by LED pulses and cosmic muons is shown as well.

  18. Balloon test project: Cosmic Ray Antimatter Calorimeter (CRAC)

    NASA Technical Reports Server (NTRS)

    Christy, J. C.; Dhenain, G.; Goret, P.; Jorand, J.; Masse, P.; Mestreau, P.; Petrou, N.; Robin, A.

    1984-01-01

    Cosmic ray observations from balloon flights are discussed. The cosmic ray antimatter calorimeter (CRAC) experiment attempts to measure the flux of antimatter in the 200-600 Mev/m energy range and the isotopes of light elements between 600 and 1,000 Mev/m.

  19. Temperature and humidity control in indirect calorimeter chambers

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A three-chamber, indirect calorimeter has been a part of the Environmental Laboratory at the U.S. Meat Animal Research Center (MARC) for over 25 yr. Corrosion of the animal chambers and unreliable temperature control forced either major repairs or complete replacement. There is a strong demand for...

  20. Progress status for the Mu2e calorimeter system

    SciTech Connect

    Pezzullo, Gianantonio; Budagov, J.; Carosi, R.; Cervelli, F.; Cheng, C.; Cordelli, M.; Corradi, G.; Davydov, Yu.; Echenard, B.; Giovannella, S.; Glagolev, V.; Happacher, F.; Hitlin, D.; Luca, A.; Martini, M.; Miscetti, S.; Murat, P.; Ongmonkolkul, P.; Porter, F.; Saputi, A.; Sarra, I.; Spinella, F.; Stomaci, V.; Tassielli, G.

    2015-02-13

    The Mu2e experiment at FNAL aims to measure the charged-lepton flavor violating neutrinoless conversion of a negative muon into an electron. The conversion results in a monochromatic electron with an energy slightly below the muon rest mass (104.97 MeV). The calorimeter should confirm that the candidates reconstructed by the extremely precise tracker system are indeed conversion electrons while performing a powerful $\\mu/e$ particle identification. Moreover, it should also provide a high level trigger for the experiment independently from the tracker system. The calorimeter should also be able to keep functionality in an environment where the background delivers a dose of ~ 10 krad/year in the hottest area and to work in the presence of 1 T axial magnetic field. These requirements translate in the design of a calorimeter with large acceptance, good energy resolution O(5%) and a reasonable position (time) resolution of ~<1 cm (<0.5ns). The baseline version of the calorimeter is composed by two disks of inner (outer) radius of 351 (660) mm filled by 1860 hexagonal $BaF_2$ crystals of 20 cm length. Each crystal is readout by two large area APD's. In this study, we summarize the experimental tests done so far as well as the simulation studies in the Mu2e environment.

  1. Progress status for the Mu2e calorimeter system

    DOE PAGES

    Pezzullo, Gianantonio; Budagov, J.; Carosi, R.; ...

    2015-02-13

    The Mu2e experiment at FNAL aims to measure the charged-lepton flavor violating neutrinoless conversion of a negative muon into an electron. The conversion results in a monochromatic electron with an energy slightly below the muon rest mass (104.97 MeV). The calorimeter should confirm that the candidates reconstructed by the extremely precise tracker system are indeed conversion electrons while performing a powerfulmore » $$\\mu/e$$ particle identification. Moreover, it should also provide a high level trigger for the experiment independently from the tracker system. The calorimeter should also be able to keep functionality in an environment where the background delivers a dose of ~ 10 krad/year in the hottest area and to work in the presence of 1 T axial magnetic field. These requirements translate in the design of a calorimeter with large acceptance, good energy resolution O(5%) and a reasonable position (time) resolution of ~<1 cm (<0.5ns). The baseline version of the calorimeter is composed by two disks of inner (outer) radius of 351 (660) mm filled by 1860 hexagonal $$BaF_2$$ crystals of 20 cm length. Each crystal is readout by two large area APD's. In this study, we summarize the experimental tests done so far as well as the simulation studies in the Mu2e environment.« less

  2. Electrical and Electrochemical Properties of Nitrogen-Containing Tetrahedral Amorphous Carbon (ta-C) Thin Films

    NASA Astrophysics Data System (ADS)

    Yang, Xingyi

    Tetrahedral amorphous carbon (ta-C) is a diamond-like carbon (DLC) material comprised of a mixture of sp2 (˜40%) and sp3-bonded (˜60%) carbon domains. The physicochemical structure and electrochemical properties depend strongly on the sp2/sp3 bonding ratio as well as the incorporation of impurities, such as hydrogen or nitrogen. The ability to grow ta-C films at lower temperatures (25-100 °C) on a wider variety of substrates is a potential advantage of these materials as compared with diamond films. In this project, the basic structural and electrochemical properties of nitrogen-incorporated ta-C thin films will be discussed. The major goal of this work was to determine if the ta-C:N films exhibit electrochemical properties more closely aligned with those of boron-doped diamond (sp 3 carbon) or glassy carbon (amorphous sp2 carbon). Much like diamond, ta-C:N thin-film electrodes are characterized by a low background voltammetric current, a wide working potential window, relatively rapid electron-transfer kinetics for aqueous redox systems, such as Fe(CN) 6-3/-4 and Ru(NH3)6+3/+2 , and weak adsorption of polar molecules from solution. For example, negligible adsorption of methylene blue was found on the ta-C:N films in contrast to glassy carbon; a surface on which this molecule strongly adsorbs. The film microstructure was studied with x-ray photoelectron microscopy (XPS), visible Raman spectroscopy and electron-energy loss spectroscopy (EELS); all of which revealed the sp2-bonded carbon content increased with increasing nitrogen. The electrical properties of ta-C:N films were studied by four-point probe resistance measurement and conductive-probe AFM (CP-AFM). The incorporation of nitrogen into ta-C films increased the electrical conductivity primarily by increasing the sp2-bonded carbon content. CP-AFM showed the distribution of the conductive sp2-carbon on the film surface was not uniform. These films have potential to be used in field emission area. The

  3. Criticality Safety Evaluation of a LLNL Training Assembly for Criticality Safety (TACS)

    SciTech Connect

    Heinrichs, D P

    2006-06-26

    Hands-on experimental training in the physical behavior of multiplying systems is one of ten key areas of training required for practitioners to become qualified in the discipline of criticality safety as identified in DOE-STD-1135-99, ''Guidance for Nuclear Criticality Safety Engineer Training and Qualification''. This document is a criticality safety evaluation of the training activities (or operations) associated with HS-3200, ''Laboratory Class for Criticality Safety''. These activities utilize the Training Assembly for Criticality Safety (TACS). The original intent of HS-3200 was to provide LLNL fissile material handlers with a practical hands-on experience as a supplement to the academic training they receive biennially in HS-3100, ''Fundamentals of Criticality Safety'', as required by ANSI/ANS-8.20-1991, ''Nuclear Criticality Safety Training''. HS-3200 is to be enhanced to also address the training needs of nuclear criticality safety professionals under the auspices of the NNSA Nuclear Criticality Safety Program.

  4. Tic versus TAC: differentiating the neuralgias (trigeminal neuralgia) from the cephalalgias (SUNCT and SUNA).

    PubMed

    VanderPluym, Juliana; Richer, Lawrence

    2015-01-01

    Trigeminal neuralgia, short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) and short-lasting unilateral neuralgiform headache attacks with autonomic symptoms (SUNA) are classified as distinct disorders in the International Classification of Headache Disorders 3 beta (ICHD-3 beta). SUNCT and SUNA are primary headache disorders included among the trigeminal autonomic cephalalgias. Trigeminal neuralgia is classified under painful cranial neuropathies and other facial pains. The classification criteria of these conditions overlap significantly which could lead to misdiagnosis. The reported overlap among these conditions has called into question whether they should be considered distinct entities or rather a continuum of the same disorder. This review explores the known overlap and how other features not included in the ICHD-3 beta criteria may better differentiate the "Tics" (trigeminal neuralgia) from the "TACs" (SUNCT and SUNA).

  5. Measured Whole-House Performance of TaC Studios Test Home

    SciTech Connect

    Butler, T.; Curtis, O.; Stephenson, R.

    2013-12-01

    As part of the NAHB Research Center Industry Partnership, Southface partnered with TaC Studios, an Atlanta-based architecture firm specializing in residential and light commercial design, on the construction of a new test home in Atlanta, GA, in the mixed humid climate. This home serves as a residence and home office for the firm's owners, as well as a demonstration of their design approach to potential and current clients. Southface believes the home demonstrates current best practices for the mixed-humid climate, including a building envelope featuring advanced air sealing details and low density spray foam insulation, glazing that exceeds ENERGY STAR requirements, and a high performance heating and cooling system. Construction quality and execution was a high priority for TaC Studios and was ensured by a third party review process. Post-construction testing showed that the project met stated goals for envelope performance, an air infiltration rate of 2.15 ACH50. The homeowners wished to further validate whole house energy savings through the project's involvement with Building America and this long-term monitoring effort. As a Building America test home, this home was evaluated to detail whole house energy use, end use loads, and the efficiency and operation of the ground source heat pump and associated systems. Given that the home includes many non-typical end use loads including a home office, pool, landscape water feature, and other luxury features not accounted for in Building America modeling tools, these end uses were separately monitored to determine their impact on overall energy consumption.

  6. Tic-Tac-Toe Performance as a Function of Maturational Level of Retarded Adolescents and Nonretarded Children

    ERIC Educational Resources Information Center

    Spitz, Herman H.; Winters, Emilia A.

    1977-01-01

    Available from: Ablex Publishing Corporation, 355 Chestnut Street, Norwood, New Jersey 07648. Two groups (36 Ss) of educable and trainable mentally retarded adolescents in an institution were compared with two groups (38 Ss) of nonretarded children (ages 8-9 years old) on a modified tic-tac-toe game for foresight in logical problem solving. (MH)

  7. [Screening hv-S/TPK from TAC library of a Triticum aestivum-Haynaldia villosa translocation line].

    PubMed

    Sun, Yulei; Cao, Aizhong; Yang, Xueming; Wang, Xiaoyun; Chen, Peidu

    2008-08-01

    Hv-S/TPK gene, a resistance related gene to powdery mildew, was cloned by using genechip, and its expression was upregulated after the inoculation of Blumeria graminis to Haynaldia villosa. Using the specific primers of Hv-S/TPK to screen a genomic TAC (Transformation-competent artificial chromosome) library of translocation line 6VS/6AL, a positive TAC was screened. A 5-kb fragment containing Hv-S/TPK was subcloned and identified. This 5160-bp fragment (GenBank Accession No. EU153366) was determined by specific primer walking. The analysis of Hv-S/TPK genomic sequence showed three introns and four extrons between start code and stop code. In the promoter region of Hv-S/TPK, there were W-box and OCS-like elements which were the elements related to disease resistance. In this study, the positive TAC clone was used to as probe in situ hybridized to mitotic metaphase chromosomes of translocation line. The result of fluorescence in situ hybridization (FISH) indicated that the TAC clone containing Hv-S/TPK was from Haynaldia villosa chromosome.

  8. CONCENTRATIONS OF PARTICULATE ORGANIC SPECIES MEASURED IN INDOOR AND OUTDOOR ENVIRONMENTS DURING THE TAMPA ASTHMATIC CHILDREN'S STUDY ( TACS )

    EPA Science Inventory

    The Tampa Asthmatic Children's Study (TACS) was completed to assess environmental exposures for a group of asthmatic children (n = 9) under the age of six and living in Tampa, Florida. Concentrations of particulate organic species are reported from residential indoor, residential...

  9. Expression of the CXCR3 ligand I-TAC by hepatocytes in chronic hepatitis C and its correlation with hepatic inflammation.

    PubMed

    Helbig, Karla J; Ruszkiewicz, Andrew; Semendric, Ljiljana; Harley, Hugh A J; McColl, Shaun R; Beard, Michael R

    2004-05-01

    The factors that regulate lymphocyte traffic in chronic hepatitis C (CHC) are not completely defined. Interferon (IFN)-inducible T cell alpha chemoattractant (I-TAC) is a relatively new member of the CXCR3 chemokine ligand family that selectively recruits activated T cells to sites of inflammation. To determine if I-TAC plays a role in CHC, we investigated I-TAC expression in hepatitis C virus (HCV)-infected liver biopsy material. I-TAC messenger RNA (mRNA) levels were significantly increased in HCV-infected liver compared with normal liver, which correlated with both portal and lobular inflammation. I-TAC expression was localized to hepatocytes throughout the liver lobule, with those in close proximity to active areas of inflammation expressing the highest concentration of I-TAC. In vitro, I-TAC mRNA and protein expression was inducible in Huh-7 cells following either IFN-alpha or -gamma stimulation and synergistically with tumor necrosis factor (TNF)-alpha. Furthermore, transfection of Huh-7 cells with either poly(I:C) or HCV RNA representing the HCV subgenomic replicon induced I-TAC mRNA expression. HCV replication was also found to modulate I-TAC expression, with stimulation of Huh-7 cells harboring either the HCV subgenomic or genomic replicon showing significantly increased synergistic effects compared with those previously seen in Huh-7 cells alone with IFN-gamma and TNF-alpha. In conclusion, these results suggest I-TAC, one of the most potent chemoattractants for activated T cells, is produced by hepatocytes in the HCV-infected liver and plays an important role in T cell recruitment and ultimately the pathogenesis of CHC.

  10. Bismuth-212-labeled anti-Tac monoclonal antibody: alpha-particle-emitting radionuclides as modalities for radioimmunotherapy

    SciTech Connect

    Kozak, R.W.; Atcher, R.W.; Gansow, O.A.; Friedman, A.M.; Hines, J.J.; Waldmann, T.A.

    1986-01-01

    Anti-Tac, a monoclonal antibody directed to the human interleukin 2 (IL-2) receptor, has been successfully conjugated to the alpha-particle-emitting radionuclide bismuth-212 by use of a bifunctional ligand, the isobutylcarboxycarbonic anhydride of diethylenetriaminepentaacetic acid. The physical properties of 212Bi are appropriate for radioimmunotherapy in that it has a short half-life, deposits its high energy over a short distance, and can be obtained in large quantities from a radium generator. Antibody specific activities of 1-40 microCi/microgram (1 Ci = 37 GBq) were achieved. Specificity of the 212Bi-labeled anti-Tac was demonstrated for the IL-2 receptor-positive adult T-cell leukemia line HUT-102B2 by protein synthesis inhibition and clonogenic assays. Activity levels of 0.5 microCi or the equivalent of 12 rad/ml of alpha radiation targeted by anti-Tac eliminated greater than 98% the proliferative capabilities of HUT-102B2 cells with more modest effects on IL-2 receptor-negative cell lines. Specific cytotoxicity was blocked by excess unlabeled anti-Tac but not by human IgG. In addition, an irrelevant control monoclonal antibody of the same isotype labeled with 212Bi was unable to target alpha radiation to cell lines. Therefore, 212Bi-labeled anti-Tac is a potentially effective and specific immunocytotoxic reagent for the elimination of IL-2 receptor-positive cells. These experiments thus provide the scientific basis for use of alpha-particle-emitting radionuclides in immunotherapy.

  11. Noise dependence with pile-up in the ATLAS Tile Calorimeter. Pile-up noise studies in the ATLAS TileCal calorimeter

    SciTech Connect

    Araque, J.P.

    2015-07-01

    The Tile Calorimeter, TileCal, is the central hadronic calorimeter of the ATLAS experiment, positioned between the electromagnetic calorimeter and the muon chambers. It comprises alternating layers of steel (as absorber material) and plastic (as active material), known as tiles. Between 2009 and 2012, the LHC has performed better than expected producing proton-proton collisions at a very high rate. These conditions are really challenging when dealing with the energy measurements in the calorimeter since not only the energy from an interesting event will be measured but a component coming from other collisions, which are difficult to distinguish from the interesting one, will also be present. This component is referred to as pile-up noise. Studies carried out to better understand how pile-up affects calorimeter noise under different circumstances are described. (author)

  12. Flow injection determination of cobalt after its sorption onto polyurethane foam loaded with 2-(2-thiazolylazo)-p-cresol (TAC).

    PubMed

    Cassella, R J; Salim, V A; Jesuíno, L S; Santelli, R E; Ferreira, S L; de Carvalho, M S

    2001-03-30

    This paper reports the development of a new methodology for determination of cobalt in water samples by using a flow injection system with loaded PUF as solid phase to preconcentrate analytes. Procedure is based on on-line retention of Co(III) ions (generated in alkaline medium by Co(II) oxidation) in a minicolumn packed with a polyether type polyurethane foam loaded with TAC (2-(2-thiazolylazo)-p-cresol) and elution with 2 mol l(-1) HCl directly to the flame atomic absorption spectrometer nebulizer. Several chemical and flow variables that could affect the performance of this system were investigated as well as the possible interferents. For 2 min of preconcentration time (10.0 ml of sample volume) the system achieved a detection limit 3.2 mug l(-1), a R.S.D. 5% at 20 mug l(-1) and an analytical throughput 24 h(-1). Whereas for 3 min of preconcentration time (15.0 ml of sample volume) a detection limit 2.4 mug l(-1), a R.S.D. under 8% at 10 mug l(-1) and a sampling frequency 17 h(-1) were reported.

  13. Silicon Photomultiplier Characterization for sPHENIX Calorimeters

    NASA Astrophysics Data System (ADS)

    Tanner, Meghan; Skoby, Michael; Aidala, Christine; Sphenix Collaboration

    2016-09-01

    Silicon photomultipliers (SiPMs) are preferable to photomultiplier tubes due to their small size, insensitivity to magnetic fields, low operating voltage, and capability of detecting single photons. The sPHENIX collaboration at RHIC will use SiPMs in their proposed electromagnetic and hadronic calorimeters. The University of Michigan is assembling and implementing a test stand to characterize the dark count rate, temperature dependence, gain, and photon detection efficiency of SiPMs. To more accurately determine the dark count rate, we have constructed a light tight box to isolate the SiPM, which surrounds an electronics enclosure that protects the SiPM circuitry, and installed software to record the output signals. With this system, we will begin to collect data and optimize the system to test arrays of SiPMs instead of single devices as the proposed calorimeters will require testing approximately 115,000 SiPMs.

  14. Micro-differential scanning calorimeter for liquid biological samples

    NASA Astrophysics Data System (ADS)

    Wang, Shuyu; Yu, Shifeng; Siedler, Michael S.; Ihnat, Peter M.; Filoti, Dana I.; Lu, Ming; Zuo, Lei

    2016-10-01

    We developed an ultrasensitive micro-DSC (differential scanning calorimeter) for liquid protein sample characterization. This design integrated vanadium oxide thermistors and flexible polymer substrates with microfluidics chambers to achieve a high sensitivity (6 V/W), low thermal conductivity (0.7 mW/K), high power resolutions (40 nW), and well-defined liquid volume (1 μl) calorimeter sensor in a compact and cost-effective way. We further demonstrated the performance of the sensor with lysozyme unfolding. The measured transition temperature and enthalpy change were in accordance with the previous literature data. This micro-DSC could potentially raise the prospect of high-throughput biochemical measurement by parallel operation with miniaturized sample consumption.

  15. Micro-differential scanning calorimeter for liquid biological samples

    SciTech Connect

    Wang, Shuyu; Yu, Shifeng; Siedler, Michael S.; Ihnat, Peter M.; Filoti, Dana I.; Lu, Ming; Zuo, Lei

    2016-10-20

    Here, we developed an ultrasensitive micro-DSC (differential scanning calorimeter) for liquid protein sample characterization. Our design integrated vanadium oxide thermistors and flexible polymer substrates with microfluidics chambers to achieve a high sensitivity (6 V/W), low thermal conductivity (0.7 mW/K), high power resolutions (40 nW), and well-defined liquid volume (1 μl) calorimeter sensor in a compact and cost-effective way. Furthermore, we demonstrated the performance of the sensor with lysozyme unfolding. The measured transition temperature and enthalpy change were in accordance with the previous literature data. This micro-DSC could potentially raise the prospect of high-throughput biochemical measurement by parallel operation with miniaturized sample consumption.

  16. Experience with a double-compensating beam calorimeter

    SciTech Connect

    Jarmie, N.; Brown, R.E.; Hardekopf, R.A.; Martinez, R.

    1982-01-01

    In an experiment to measure the D(t,..cap alpha..)n cross section at beam energies of 10 to 120 keV, we have developed a double-compensating beam calorimeter, based on a Swiss design to measure the partical beam intensity. A Faraday cup is not useful because of considerable charge exchange in the target gas at such low beam energies. We calibrated the calorimeter both with 10- and 3-MeV protons (comparing with a Faraday-cup measurement of the beam flux) and with the heat generated in a precision resistor. Both methods agree and give a calibration accurate to +- 0.08% over a range of 10 to 800 mW beam power. Beam powers as low as 5 mW may be used, but with less accuracy. The beam energy must be known in order to calculate the particle intensity. Some difficulties with and peculiarities of the device are discussed.

  17. Scanning calorimeter for nanoliter-scale liquid samples

    NASA Astrophysics Data System (ADS)

    Olson, E. A.; Efremov, M. Yu.; Kwan, A. T.; Lai, S.; Petrova, V.; Schiettekatte, F.; Warren, J. T.; Zhang, M.; Allen, L. H.

    2000-10-01

    We introduce a scanning calorimeter for use with a single solid or liquid sample with a volume down to a few nanoliters. Its use is demonstrated with the melting of 52 nL of indium, using heating rates from 100 to 1000 K/s. The heat of fusion was measured to within 5% of the bulk value, and the sensitivity of the measurement was ±7 μW. The heat of vaporization of water was measured in the scanning mode to be within ±23% of the bulk value by actively vaporizing water droplets from 2 to 100 nL in volume. Results within 25% were obtained for the heat of vaporization by using the calorimeter in a heat-conductive mode and measuring the passive evaporation of water. Temperature measurements over a period of 10 h had a standard deviation of 3 mK.

  18. ANL four-meter calorimeter design and operation manual

    SciTech Connect

    Perry, R.B.; Lewis, R.N.; Youngdahl, G.A.; Jung, E.A.; Roche, C.T.

    1980-02-01

    The four-meter fuel rod calorimetric system measures the thermal power produced by radioactive decay of fuel rods containing Pu. The Pu mass is related to the measured power through the weighted average of the product of the isotopic decay energies and the decay constants of the Pu isotopes present. U content has no effect since the thermal power produced by the U nuclides is insignificant when compared to Pu. Radiations from Pu are alpha particles and low-energy photons. This calorimeter will measure samples producing power up to 1.5 watts at a rate of one sample every 120 min. The instrument consists of a data-acquisition module made up of a microprocessor, with an 8K-byte nonvolatile memory, a control cabinet and the calorimeter chamber. (FS)

  19. Verification of Electromagnetic Calorimeter Concept for the HADES spectrometer

    NASA Astrophysics Data System (ADS)

    Svoboda, O.; Blume, C.; Czyžycki, W.; Epple, E.; Fabbietti, L.; Galatyuk, T.; Golubeva, M.; Guber, F.; Hlaváč, S.; Ivashkin, A.; Kajetanowic, M.; Kardan, B.; Koenig, W.; Kugler, A.; Lapidus, K.; Linev, S.; Lisowski, E.; Ott, P.; Otte, P.; Petukhov; Pietraszko, J.; Reshetin, A.; Rodríguez-Ramos, P.; Rost, A.; Salabura, P.; Skott, P.; Sobolev, Y. G.; Steffen, O.; Thomas, A.; Tlustý, P.; Traxler, M.

    2015-04-01

    The HADES spectrometer currently operating on the beam of SIS18 accelerator in GSI will be moved to a new position in the CBM cave of the future FAIR complex. Electromagnetic calorimeter (ECAL) will enable the HADES@FAIR experiment to measure data on neutral meson production in heavy ion collisions at the energy range of 2-10 A GeVon the beam of the new accelerator SIS100. Calorimeter will be based on 978 massive lead glass modules read out by photomultipliers and a novel front-end electronics. Secondary gamma beam with energies ranging from 81 MeV up to 1399 MeV from MAMI-C Mainz facility was used to verify selected technical solutions. Relative energy resolution was measured using modules with three different types of photomultipliers. Two types of developed front-end electronics as well as energy leakage between neighbouring modules under parallel and declined gamma beams were studied in detail.

  20. Geometric calibration of the SND detector electromagnetic calorimeter

    NASA Astrophysics Data System (ADS)

    Korol, A. A.; Melnikova, N. A.

    2017-03-01

    This paper presents the design, implementation and validation of the software alignment procedure used to perform geometric calibration of the electromagnetic calorimeter with respect to the tracking system of the SND detector which is taking data at the VEPP-2000 e+e- collider (BINP, Novosibirsk). This procedure is based on the mathematical model describing the relative calorimeter position. The parameter values are determined by minimizing a χ2 function using the difference between particle directions reconstructed in these two subdetectors for e+e- →e+e- scattering events. The results of the calibration applied to data and MC simulation fit the model well and give an improvement in particle reconstruction. They are used in data reconstruction and MC simulation.

  1. Micro-differential scanning calorimeter for liquid biological samples

    DOE PAGES

    Wang, Shuyu; Yu, Shifeng; Siedler, Michael S.; ...

    2016-10-20

    Here, we developed an ultrasensitive micro-DSC (differential scanning calorimeter) for liquid protein sample characterization. Our design integrated vanadium oxide thermistors and flexible polymer substrates with microfluidics chambers to achieve a high sensitivity (6 V/W), low thermal conductivity (0.7 mW/K), high power resolutions (40 nW), and well-defined liquid volume (1 μl) calorimeter sensor in a compact and cost-effective way. Furthermore, we demonstrated the performance of the sensor with lysozyme unfolding. The measured transition temperature and enthalpy change were in accordance with the previous literature data. This micro-DSC could potentially raise the prospect of high-throughput biochemical measurement by parallel operation with miniaturizedmore » sample consumption.« less

  2. Boronated Scintillator Detector for Use in Space with Ionization Calorimeters

    NASA Astrophysics Data System (ADS)

    Britvich, G. I.; Chernichenko, S. K.; Demichev, M. A.; Gnezdilov, I. I.; Mukhin, V. I.; Soukhih, A. V.

    2016-02-01

    Boronated Scintillator Detector (BSD) for use in space with ionization calorimeters was suggested. BSD improved e/h showers separation, which are initiated in the ionization calorimeter in interaction it with high energy particles. Improve the rejection is based on the hadron-induced showers tend to be accompanied by significantly more neutron activity than electromagnetic showers. The detector is composed of natural boron-loaded (5%) castable plastic scintillation plates. To collect light using wavelength-shifting (WLS) fibers. The experiment showed that the photoelectron yield is ∼ 40 ph.el./MeV with using PMT EMI 9954KB. Simulation on GEANT4 was obtained neutron detection efficiency. The simulation was conducted in the assumption that neutrons have the spectrum 252Cf and fall plane-parallel on the entry surface of the detector.

  3. The readout driver (ROD) for the ATLAS liquid argon calorimeters

    NASA Astrophysics Data System (ADS)

    Efthymiopoulos, Ilias

    2001-04-01

    The Readout Driver (ROD) for the Liquid Argon calorimeter of the ATLAS detector is described. Each ROD module receives triggered data from 256 calorimeter cells via two fiber-optics 1.28 Gbit/s links with a 100 kHz event rate (25 kbit/event). Its principal function is to determine the precise energy and timing of the signal from discrete samples of the waveform, taken each period of the LHC clock (25 ns). In addition, it checks, histograms, and formats the digital data stream. A demonstrator system, consisting of a motherboard and several daughter-board processing units (PUs) was constructed and is currently used for tests in the lab. The design of this prototype board is presented here. The board offers maximum modularity and allows the development and testing of different PU designs based on today's leading integer and floating point DSPs.

  4. Active radiometric calorimeter for absolute calibration of radioactive sources

    SciTech Connect

    Stump, K.E.; DeWerd, L.A.; Rudman, D.A.; Schima, S.A.

    2005-03-01

    This report describes the design and initial noise floor measurements of a radiometric calorimeter designed to measure therapeutic medical radioactive sources. The instrument demonstrates a noise floor of approximately 2 nW. This low noise floor is achieved by using high temperature superconducting (HTS) transition edge sensor (TES) thermometers in a temperature-control feedback loop. This feedback loop will be used to provide absolute source calibrations based upon the electrical substitution method. Other unique features of the calorimeter are (a) its ability to change sources for calibration without disrupting the vacuum of the instrument, and (b) the ability to measure the emitted power of a source in addition to the total contained source power.

  5. The iMPACT project tracker and calorimeter

    NASA Astrophysics Data System (ADS)

    Mattiazzo, S.; Bisello, D.; Giubilato, P.; Pantano, D.; Pozzobon, N.; Snoeys, W.

    2017-02-01

    In recent years the use of hadrons for cancer radiation treatment has grown in importance, and many facilities are currently operational or under construction worldwide. To fully exploit the therapeutic advantages offered by hadron therapy, precise body imaging for accurate beam delivery is decisive. While traditional X-ray Computed Tomography (xCT) fails in providing 3D images with the precision required for hadrons treatment guidance, Proton Computer Tomography (pCT) scanners, currently in their R&D phase, can. A pCT scanner consists of a tracker system, to track protons, and of a calorimeter, to measure their residual energy. In this paper we will present the iMPACT project, which foresees a novel proton tracking detector with higher scanning speed, better spatial resolution and lower material budget with respect to present state-of-the-art detectors, leading to enhanced performances. The tracker will be matched to a fast, highly segmented proton range calorimeter.

  6. Development of an air flow thermal balance calorimeter

    NASA Technical Reports Server (NTRS)

    Sherfey, J. M.

    1972-01-01

    An air flow calorimeter, based on the idea of balancing an unknown rate of heat evolution with a known rate of heat evolution, was developed. Under restricted conditions, the prototype system is capable of measuring thermal wattages from 10 milliwatts to 1 watt, with an error no greater than 1 percent. Data were obtained which reveal system weaknesses and point to modifications which would effect significant improvements.

  7. On timing properties of LYSO-based calorimeters

    SciTech Connect

    Anderson, D.; Apresyan, A.; Bornheim, A.; Duarte, J.; Pena, C.; Ronzhin, A.; Spiropulu, M.; Trevor, J.; Xie, S.

    2015-04-23

    We present test beam studies and results on the timing performance and characterization of the time resolution of Lutetium–Yttrium Orthosilicate (LYSO)-based calorimeters. We also demonstrate that a time resolution of 30 ps is achievable for a particular design. Additionally, we discuss precision timing calorimetry as a tool for the mitigation of physics object performance degradation effects due to the large number of simultaneous interactions in the high luminosity environment foreseen at the Large Hadron Collider.

  8. Micro-Fabricated DC Comparison Calorimeter for RF Power Measurement

    PubMed Central

    Neji, Bilel; Xu, Jing; Titus, Albert H.; Meltzer, Joel

    2014-01-01

    Diode detection and bolometric detection have been widely used to measure radio frequency (RF) power. However, flow calorimeters, in particular micro-fabricated flow calorimeters, have been mostly unexplored as power meters. This paper presents the design, micro-fabrication and characterization of a flow calorimeter. This novel device is capable of measuring power from 100 μW to 200 mW. It has a 50-Ohm load that is heated by the RF source, and the heat is transferred to fluid in a microchannel. The temperature change in the fluid is measured by a thermistor that is connected in one leg of a Wheatstone bridge. The output voltage change of the bridge corresponds to the RF power applied to the load. The microfabricated device measures 25.4 mm × 50.8 mm, excluding the power supplies, microcontroller and fluid pump. Experiments demonstrate that the micro-fabricated sensor has a sensitivity up to 22 × 10−3 V/W. The typical resolution of this micro-calorimeter is on the order of 50 μW, and the best resolution is around 10 μW. The effective efficiency is 99.9% from 0–1 GHz and more than 97.5% at frequencies up to 4 GHz. The measured reflection coefficient of the 50-Ohm load and coplanar wave guide is less than −25 dB from 0–2 GHz and less than −16 dB at 2–4 GHz. PMID:25350509

  9. The large-scale anisotropy with the PAMELA calorimeter

    NASA Astrophysics Data System (ADS)

    Karelin, A.; Adriani, O.; Barbarino, G.; Bazilevskaya, G.; Bellotti, R.; Boezio, M.; Bogomolov, E.; Bongi, M.; Bonvicini, V.; Bottai, S.; Bruno, A.; Cafagna, F.; Campana, D.; Carbone, R.; Carlson, P.; Casolino, M.; Castellini, G.; De Donato, C.; De Santis, C.; De Simone, N.; Di Felice, V.; Formato, V.; Galper, A.; Koldashov, S.; Koldobskiy, S.; Krut'kov, S.; Kvashnin, A.; Leonov, A.; Malakhov, V.; Marcelli, L.; Martucci, M.; Mayorov, A.; Menn, W.; Mergé, M.; Mikhailov, V.; Mocchiutti, E.; Monaco, A.; Mori, N.; Munini, R.; Osteria, G.; Palma, F.; Panico, B.; Papini, P.; Pearce, M.; Picozza, P.; Ricci, M.; Ricciarini, S.; Sarkar, R.; Simon, M.; Scotti, V.; Sparvoli, R.; Spillantini, P.; Stozhkov, Y.; Vacchi, A.; Vannuccini, E.; Vasilyev, G.; Voronov, S.; Yurkin, Y.; Zampa, G.; Zampa, N.

    2015-10-01

    The large-scale anisotropy (or the so-called star-diurnal wave) has been studied using the calorimeter of the space-born experiment PAMELA. The cosmic ray anisotropy has been obtained for the Southern and Northern hemispheres simultaneously in the equatorial coordinate system for the time period 2006-2014. The dipole amplitude and phase have been measured for energies 1-20 TeV n-1.

  10. After-burning of nitropenta products in a calorimeter

    SciTech Connect

    Kuhl, A L; Neuwald, P; Reichenbach, H

    1999-06-18

    Explored here are the ''after-burning'' effects for explosions of Nitropenta (NP) charges in air. Detonation of the charge transforms the solid explosive ( C HNO 5 8412 , also known as PETN) into gaseous products that are rich in carbon and CO, which subsequently act as a fuel. When these hot ({approximately}3500 K) gases mix with air, rapid combustion (after-burning) takes place. The dynamics of this exothermic process was studied in ''pressure calorimeter'' experiments performed at EMI.

  11. An electromagnetic calorimeter for the JLab real compton scattering experiment

    NASA Astrophysics Data System (ADS)

    Hamilton, D. J.; Shahinyan, A.; Wojtsekhowski, B.; Annand, J. R. M.; Chang, T.-H.; Chudakov, E.; Danagoulian, A.; Degtyarenko, P.; Egiyan, K.; Gilman, R.; Gorbenko, V.; Hines, J.; Hovhannisyan, E.; Hyde-Wright, C. E.; de Jager, C. W.; Ketikyan, A.; Mamyan, V. H.; Michaels, R.; Nathan, A. M.; Nelyubin, V.; Rachek, I.; Roedelbrom, M.; Petrosyan, A.; Pomatsalyuk, R.; Popov, V.; Segal, J.; Shestakov, Y.; Templon, J.; Voskanyan, H.

    2011-07-01

    A lead-glass hodoscope calorimeter that was constructed for use in the Jefferson Lab Real Compton Scattering experiment is described. The detector provides a measurement of the coordinates and the energy of scattered photons in the GeV energy range with resolutions of 5 mm and 6%/ √{Eγ GeV}. Features of both the detector design and its performance in the high luminosity environment during the experiment are presented.

  12. Calibration and Characterization of the Small Sample Calorimeter

    SciTech Connect

    Santi, Peter A.; Perry, Katherine A.

    2012-08-13

    An early component of the Joint Fuel Cycle Study (JFCS) between the United States and the Republic of Korea is a test of gram scale electrochemical recycling of spent fuel which is to be performed at Idaho National Laboratory (INL). Included in this test is the development of Nondestructive Assay (NDA) technologies that would be applicable for International Atomic Energy Agency (IAEA) safeguards of the electrochemical recycling process. Of upmost importance to safeguarding the fuel cycle associated with the electrochemical recycling process is the ability to safeguard the U/TRU ingots that will be produced in the process. For the gram scale test, the ingots that will be produced will have an expected thermal power of approximately 130 mW. To ascertain how well the calorimetric assay NDA technique can perform in assaying these ingots, Los Alamos National Laboratory (LANL) has characterized and calibrated a small solid-state calorimeter called the Small Sample Calorimeter (SSC3) to perform these measurements at LANL. To calibrate and characterize the SSC3, a series of measurements were performed using certified {sup 238}Pu heat standards whose power output is traceable back to the National Institute of Standards and Technology (NIST) electrical standards. The results of these measurements helped establish both the calibration of the calorimeter as well as the expected performance of the calorimeter in terms of its accuracy and precision as a function of thermal power of the item that is being measured. In this report, we will describe the measurements that were performed and provide a discussion of the results of these measurements.

  13. The backward end-cap for the PANDA electromagnetic calorimeter

    NASA Astrophysics Data System (ADS)

    Capozza, L.; Maas, F. E.; Noll, O.; Rodriguez Pineiro, D.; Valente, R.

    2015-02-01

    The PANDA experiment at the new FAIR facility will cover a broad experimental programme in hadron structure and spectroscopy. As a multipurpose detector, the PANDA spectrometer needs to ensure almost 4π coverage of the scattering solid angle, full and accurate multiple-particle event reconstruction and very good particle identification capabilities. The electromagnetic calorimeter (EMC) will be a key item for many of these aspects. Particle energies ranging from some MeVs to several GeVs have to be measured with a relative resolution of 1% ⊕ 2%/√E/GeV . It will be a homogeneous calorimeter made of PbWO4 crystals and will be operated at -25°C, in order to improve the scintillation light yield. With the exception of the very forward section, the light will be detected by large area avalanche photodiodes (APDs). The current pulses from the APDs will be integrated, amplified and shaped by ASIC chips which were developed for this purpose. The whole calorimeter has been designed in three sections: a forward end-cap, a central barrel and a backward end-cap (BWEC). In this contribution, a status report on the development of the BWEC is presented.

  14. Longitudinally segmented shashlik calorimeters with SiPM readout

    NASA Astrophysics Data System (ADS)

    Berra, A.; Cecchini, S.; Cindolo, F.; Ferdinando, D. Di; Jollet, C.; Longhin, A.; Ludovici, L.; Mandrioli, G.; Mauri, N.; Meregaglia, A.; Paoloni, A.; Pasqualini, L.; Patrizii, L.; Pozzato, M.; Pupilli, F.; Prest, M.; Sirri, G.; Terranova, F.; Vallazza, E.; Votano, L.

    2017-02-01

    The goal of the INFN SCENTT R&D project is to develop the calorimeter technologies for the instrumentation of decay tunnels in conventional neutrino beams. This instrumentation is required to achieve a substantial improvement in the uncertainty on neutrino fluxes for the next generation cross section experiments. In particular, we are designing a positron tagger based on purely calorimetric techniques that is able to measure the rate and the spectrum of the positrons produced in the K+ →e+π0νe decay. The νe flux is inferred from the positron rate in the decay tunnel. Considering the large dimensions of the tagger, the most cost effective technology is based on small modules of Fe/Scintillator shashlik calorimeters, with adequate segmentation and energy resolution to efficiently tag the positrons over the charged pion background. This contribution presents preliminary results obtained with two shashlik calorimeter prototypes readout with an array of Silicon PhotoMultipliers and tested at the CERN PS-T9 beamline.

  15. Hadronic Showers in a Highly Granular Imaging Calorimeter

    NASA Astrophysics Data System (ADS)

    Kaplan, A.; The Calice Collaboration

    The CALICE collaboration develops highly granular calorimeter prototypes to evaluate technologies for experiments at a future lepton collider. The analogue hadronic calorimeter prototype consists of steel absorber plates interleaved with 38 active plastic scintillator layers which are sub-divided into small tiles. In total 7608 tiles are read out individually via embedded Silicon Photomultipliers. The prototype is one of the first large scale applications of these novel and very promising miniature photodetectors. Since 2006, the calorimeter has been operated in combined test beam setups at DESY, CERN and FNAL. The high-resolution 3D image data with analogue energy information are used to study properties and composition of hadronic showers at a new level of detail. This helps to constrain hadronic shower models through comparisons with model calculations. The spatial shower development and the substructure of the showers, compared to a variety of different Geant 4 shower models including decompositions into individual shower components are presented. Aspects of the energy reconstruction of hadronic showers, such as Particle Flow, are discussed.

  16. Electromagnetic Calorimeter studies for the GEp(5) experiment

    NASA Astrophysics Data System (ADS)

    Ayerbe Gayoso, Carlos

    2013-10-01

    The GEp(5) experiment, part of the SBS collaboration, will be the fourth measurement of the GEp /GMp ratio using the proton recoil polarization technique. The current data suggests that the GEp /GMp ratio obtained with this technique, might cross zero near Q2 ~ 10 GeV2 , now reachable with the CEBAF upgrade to 12 GeV energy beam. This measurement technique requires a precise measurement of the energy and angles of the scattered electron in coincidence with the recoil proton. The electron's measured energy and crude position will be used in the trigger, while the offline position measurement will be used in kinematic cuts to separate the elastic process from the background. A lead-glass calorimeter, which was used in the previous experiments, is not optimal for the planned experiment due to the rapid radiation damage in the experiment's running conditions. A sampling calorimeter, made of lead and plastic scintillators, is under consideration. Results from a test beam and Monte Carlo simulations of this kind of calorimeter will be presented. Supported from a NSF grant, PHY-1066374.

  17. Applying fast calorimetry on a spent nuclear fuel calorimeter

    SciTech Connect

    Liljenfeldt, Henrik

    2015-04-15

    Recently at Los Alamos National Laboratory, sophisticated prediction algorithms have been considered for the use of calorimetry for treaty verification. These algorithms aim to predict the equilibrium temperature based on early data and therefore be able to shorten the measurement time while maintaining good accuracy. The algorithms have been implemented in MATLAB and applied on existing equilibrium measurements from a spent nuclear fuel calorimeter located at the Swedish nuclear fuel interim storage facility. The results show significant improvements in measurement time in the order of 15 to 50 compared to equilibrium measurements, but cannot predict the heat accurately in less time than the currently used temperature increase method can. This Is both due to uncertainties in the calibration of the method as well as identified design features of the calorimeter that limits the usefulness of equilibrium type measurements. The conclusions of these findings are discussed, and suggestions of both improvements of the current calorimeter as well as what to keep in mind in a new design are given.

  18. The calorimeter of the Mu2e experiment at Fermilab

    DOE PAGES

    Atanov, N.; Baranov, V.; Budagov, J.; ...

    2017-01-23

    Here, the Mu2e experiment at Fermilab looks for Charged Lepton Flavor Violation (CLFV) improving by 4 orders of magnitude the current experimental sensitivity for the muon to electron conversion in a muonic atom. A positive signal could not be explained in the framework of the current Standard Model of particle interactions and therefore would be a clear indication of new physics. In 3 years of data taking, Mu2e is expected to observe less than one background event mimicking the electron coming from muon conversion. Achieving such a level of background suppression requires a deep knowledge of the experimental apparatus: amore » straw tube tracker, measuring the electron momentum and time, a cosmic ray veto system rejecting most of cosmic ray background and a pure CsI crystal calorimeter, that will measure time of flight, energy and impact position of the converted electron. The calorimeter has to operate in a harsh radiation environment, in a 10-4 Torr vacuum and inside a 1 T magnetic field. The results of the first qualification tests of the calorimeter components are reported together with the energy and time performances expected from the simulation and measured in beam tests of a small scale prototype.« less

  19. The calorimeter of the Mu2e experiment at Fermilab

    NASA Astrophysics Data System (ADS)

    Atanov, N.; Baranov, V.; Budagov, J.; Cervelli, F.; Colao, F.; Cordelli, M.; Corradi, G.; Dané, E.; Davydov, Y. I.; Di Falco, S.; Diociaiuti, E.; Donati, S.; Donghia, R.; Echenard, B.; Flood, K.; Giovannella, S.; Glagolev, V.; Grancagnolo, F.; Happacher, F.; Hitlin, D. G.; Martini, M.; Miscetti, S.; Miyashita, T.; Morescalchi, L.; Murat, P.; Pezzullo, G.; Porter, F.; Raffaelli, F.; Radicioni, T.; Ricci, M.; Saputi, A.; Sarra, I.; Spinella, F.; Tassielli, G.; Tereshchenko, V.; Usubov, Z.; Zhu, R. Y.

    2017-01-01

    The Mu2e experiment at Fermilab looks for Charged Lepton Flavor Violation (CLFV) improving by 4 orders of magnitude the current experimental sensitivity for the muon to electron conversion in a muonic atom. A positive signal could not be explained in the framework of the current Standard Model of particle interactions and therefore would be a clear indication of new physics. In 3 years of data taking, Mu2e is expected to observe less than one background event mimicking the electron coming from muon conversion. Achieving such a level of background suppression requires a deep knowledge of the experimental apparatus: a straw tube tracker, measuring the electron momentum and time, a cosmic ray veto system rejecting most of cosmic ray background and a pure CsI crystal calorimeter, that will measure time of flight, energy and impact position of the converted electron. The calorimeter has to operate in a harsh radiation environment, in a 10‑4 Torr vacuum and inside a 1 T magnetic field. The results of the first qualification tests of the calorimeter components are reported together with the energy and time performances expected from the simulation and measured in beam tests of a small scale prototype.

  20. A photon calorimeter using lead tungstate crystals for the CEBAF HAll A Compton polarimeter

    SciTech Connect

    D. Neyret; T. Pussieux; T. Auger; M. Baylac; E. Burtin; C. Cavata; R. Chipaux; S. Escoffier; N. Falletto; J. Jardillier; S. Kerhoas; D. Lhuillier; F. Marie; C. Veyssiere; J. Ahrens; R. Beck; M. Lang

    2000-05-01

    A new Compton polarimeter is built on the CEBAF Hall A electron beam line. Performances of 10% resolution and 1% calibration are required for the photon calorimeter of this polarimeter. This calorimeter is built with lead tungstate scintillators coming from the CMS electromagnetic calorimeter R&D. Beam tests of this detector have been made using the tagged photon beam line at MAMI, Mainz, and a resolution of 1.76%+2.75%/v+0.41%/E has been measured.

  1. Precision closed bomb calorimeter for testing flame and gas producing initiators

    NASA Technical Reports Server (NTRS)

    Carpenter, D. R., Jr.; Taylor, A. C., Jr.

    1972-01-01

    A calorimeter has been developed under this study to help meet the needs of accurate performance monitoring of electrically or mechanically actuated flame and gas producing devices, such as squib-type initiators. A ten cubic centimeter closed bomb (closed volume) calorimeter was designed to provide a standard pressure trace and to measure a nominal 50 calorie output, using the basic components of a Parr Model 1411 calorimeter. Two prototype bombs were fabricated, pressure tested to 2600 psi, and extensively evaluated.

  2. SUITABILITY OF A NEW CALORIMETER FOR EXOTIC MESON SEARCHES

    SciTech Connect

    Bookwalter, C.; Ostrovidov, A.; Eugenio, P.

    2007-01-01

    Exotic mesons, particles that have quantum numbers that are inaccessible to conventional quark-model mesons, are predicted by quantum chromodynamics (QCD), but past experiments seeking to identify exotic candidates have produced controversial results. The HyCLAS experiment (E04005) at Thomas Jefferson National Accelerator Facility (TJNAF) proposes the use of the Continuous Electron Beam Accelerator Facility (CEBAF) Large Acceptance Spectrometer (CLAS) in Hall B to study the photoproduction of exotic mesons. However, the base detector package at CLAS is not ideal for observing and measuring neutral particles, particularly at forward angles. The Deeply Virtual Compton Scattering (DVCS) experiment at TJNAF has commissioned a new calorimeter for detecting small-angle photons, but studies must be performed to determine its suitability for a meson spectroscopy experiment. The ηπ system has been under especial scrutiny in the community as a source for potential exotics, so the new calorimeter’s ability at reconstructing these resonances must be evaluated. To achieve this, the invariant mass of showers in the calorimeter are reconstructed. Also, two electroproduction reaction channels analogous to photoproduction channels of interest to HyCLAS are examined in DVCS data. It is found that, while not ideal, the new calorimeter will allow access to additional reaction channels, and its inclusion in HyCLAS is warranted. Results in basic shower reconstruction show that the calorimeter has good effi ciency in resolving π° decays, but its η reconstruction is not as strong. When examining ep → epπ°η, preliminary reconstruction of the ηπ° system shows faint signals in the a0(980) region. In the ep → e n π+ η channel, preliminary reconstruction of the ηπ+ system gave good signals in the a0(980) and a2(1320) regions, but statistics were poor. While more analyses are necessary to improve statistics and remove background, these preliminary results support the claim

  3. Tests of the D0 calorimeter response in 2--150 GeV beams

    SciTech Connect

    De, K. . Dept. of Physics)

    1992-10-01

    At the heart of the D0 detector, which recently started its maiden data run at the Fermilab Tevatron p[bar p] collider, is a finely segmented hermetic large angle liquid argon calorimeter. We present here results from the latest test beam studies of the calorimeter in 1991. Modules from the central calorimeter, end calorimeter and the inter-cryostat detector were included in this run. New results on resolution, uniformity and linearity will be presented with electron and pion beams of various energies. Special emphasis will be placed on first results from the innovative technique of using scintillator sampling in the intermediate rapidity region to improve uniformity and hermeticity.

  4. Tests of the D0 calorimeter response in 2--150 GeV beams

    SciTech Connect

    De, K.; D0 Collaboration

    1992-10-01

    At the heart of the D0 detector, which recently started its maiden data run at the Fermilab Tevatron p{bar p} collider, is a finely segmented hermetic large angle liquid argon calorimeter. We present here results from the latest test beam studies of the calorimeter in 1991. Modules from the central calorimeter, end calorimeter and the inter-cryostat detector were included in this run. New results on resolution, uniformity and linearity will be presented with electron and pion beams of various energies. Special emphasis will be placed on first results from the innovative technique of using scintillator sampling in the intermediate rapidity region to improve uniformity and hermeticity.

  5. Evaluation of Variants of 3M Peltor ComTAC Tactical Communication and Protection System (TCAPS) Headsets: Measures of Hearing Protection and Auditory Performance

    DTIC Science & Technology

    2013-09-01

    sound source azimuth. With the exception of the bare head condition, a helmet was always worn , and with the exception of the ComTAC III ARC-carbon...lightweight carbon helmets were worn in combination with the ComTAC III ARC headset to measure the difference in their effect on auditory localization ability...the ComTAC III ARC TCAPS is designed to mount on the Ops-Core FAST helmet accessory rail connector system, all TCAPS were evaluated in combination

  6. Growth of Low Defect Density Gallium Nitride (GaN) Films on Novel Tantalum Carbide (TaC) Substrates for Improved Device Performance

    DTIC Science & Technology

    2009-05-01

    on SiC substrates by pulse laser deposition (PLD) (10) and on magnesium oxide ( MgO ) substrates by electron beam evaporation (11), using TaC films...matched to GaN than currently used substrates. We created the TaC substrate, using pulse laser deposition (PLD) of TaC onto (0001) SiC substrates at...films grown on SiC or sapphire, and they contained more than an order of magnitude fewer dislocations compared to a typical value of 4 x 109 cm–2

  7. Microstructure and Scratch Resistance of TaC Dense Ceramic Layer on an Iron Matrix

    NASA Astrophysics Data System (ADS)

    Zhao, Nana; Xu, Yunhua; Zhong, Lisheng; Yan, Honghua; Ovcharenko, Vladimir E.

    2016-06-01

    A tantalum carbide dense ceramic layer with a thickness of ~20 μm was produced on the surface of an iron matrix using an in situ technique. The morphology, microstructure, and phase composition of the layer were characterized by means of SEM, TEM, and XRD. The results show fairly agglomerated and uniformly sized (~200 nm) TaC particulates with a face-cantered cubic structure. The values of nano-hardness for the surface and cross section of reinforcing layer can be as high as 29.5 ± 0.6 and 26.7 ± 0.1 GPa, respectively, which were analyzed using a nano-indentation apparatus. Moreover, the scratch resistance of the layer was measured by scratch tests under a progressively increasing load of 0-100 N. A high critical load of 90.4 N is obtained. It is worthy to note that there are only cracking, slight splitting, and small flaking pits (even at the maximum load) all over the whole scratch process, namely the reinforcing layer can protect the iron matrix from serious abrasion effectively. In addition, the excellent scratch resistance and mechanism are discussed in detail.

  8. How autonomy and the web are taking the people out of TacSat-2

    NASA Astrophysics Data System (ADS)

    Finley, Charles J.

    2006-05-01

    One of the most costly components of the on-orbit operation of a spacecraft is the people that execute the mission. Historically, for Air Force Research Laboratory (AFRL) and the Department of Defense Space Test Program (STP) research and development, test and evaluation (RDT&E) space missions, a team of fifteen personnel maintains 24-hour coverage for the three-week Launch and Early Operations (L/EO) phase of the mission and four one-week L/EO rehearsals. During the Nominal Operations phase of the mission, 2.5 "man-days" of support are necessary each day that the spacecraft remains on-orbit, as well as during the two, week-long, nominal operations rehearsals. Therefore, the mission-dedicated personnel contribution to the cost of a one-year mission is more than eleven man-years, and this does not include the personnel that actually operate the antennas at the various remote ground facilities or develop and maintain the mission-specific or shared-use ground network, hardware, and software. In the low-budget RDT&E world, hardware, software, or Concept of Operations (CONOPS) developments that significantly reduce the necessary Operations personnel investment can mean the difference between a mission that does or does not survive. This paper explores the CONOPS and suite of tools that the TacSat-2 program has put together to achieve maximum mission effectiveness at minimum manpower cost.

  9. CaloCube: A new-concept calorimeter for the detection of high-energy cosmic rays in space

    NASA Astrophysics Data System (ADS)

    Vannuccini, E.; Adriani, O.; Agnesi, A.; Albergo, S.; Auditore, L.; Basti, A.; Berti, E.; Bigongiari, G.; Bonechi, L.; Bonechi, S.; Bongi, M.; Bonvicini, V.; Bottai, S.; Brogi, P.; Carotenuto, G.; Castellini, G.; Cattaneo, P. W.; D'Alessandro, R.; Detti, S.; Fasoli, M.; Finetti, N.; Lenzi, P.; Maestro, P.; Marrocchesi, P. S.; Miritello, M.; Mori, N.; Orzan, G.; Olmi, M.; Pacini, L.; Papini, P.; Pellegriti, M. G.; Pirzio, F.; Rappoldi, A.; Ricciarini, S.; Spillantini, P.; Starodubtsev, O.; Stolzi, F.; Suh, J. E.; Sulaj, A.; Tiberio, A.; Tricomi, A.; Trifiro, A.; Trimarchi, M.; Vedda, A.; Zampa, G.; Zampa, N.; Zerbo, B.

    2017-02-01

    The direct observation of high-energy cosmic rays, up to the PeV region, will increasingly rely on highly performing calorimeters, and the physics performance will be primarily determined by their geometrical acceptance and energy resolution. Thus, it is extremely important to optimize their geometrical design, granularity, and absorption depth, with respect to the total mass of the apparatus, which is among the most important constraints for a space mission. Calocube is a homogeneous calorimeter whose basic geometry is cubic and isotropic, so as to detect particles arriving from every direction in space, thus maximizing the acceptance; granularity is obtained by filling the cubic volume with small cubic scintillating crystals. This design forms the basis of a three-year R &D activity which has been approved and financed by INFN. A comparative study of different scintillating materials has been performed. Optimal values for the size of the crystals and spacing among them have been studied. Different geometries, besides the cubic one, and the possibility to implement dual-readout techniques have been investigated. A prototype, instrumented with CsI(Tl) cubic crystals, has been constructed and tested with particle beams. An overview of the obtained results will be presented and the perspectives for future space experiments will be discussed.

  10. How Specialised Are Specialists? Generalisation Properties of Entries from the 2008 and 2009 TAC Market Design Competitions

    NASA Astrophysics Data System (ADS)

    Robinson, Edward; McBurney, Peter; Yao, Xin

    Unlike the classic Trading Agent competition (TAC), where participants enter trading strategies into a market, the TAC Market Design Competition (CAT) allows participants to create rules for their own double auction market and set fees for traders, which they embody in agents known as specialists. Although the generalisation properties of traders when the specialist (i.e., the market mechanism) is fixed have been assessed, generalisation properties of specialists have not. It is unclear whether and how a specialist might (intentionally or unintentionally) favour certain trading strategies. We present an empirical analysis of specialists' generalisation abilities in various trading environments. Our results show that specialists can be sensitive to a number of factors, including the other trading and specialist strategies in the environment.

  11. U.S. Accession to the Association of Southeast Asian Nations? Treaty of Amity and Cooperation (TAC)

    DTIC Science & Technology

    2009-07-13

    PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) 11. SPONSOR...to maintain or expand sanctions on Burma. Proponents of accession often note that Australia has imposed and expanded financial and travel ...prior to its accession to the TAC. Australia’s October 2007 promulgation of targeted financial and travel restrictions on over 400 members of the

  12. Solar Technology Acceleration Center (SolarTAC): Cooperative Research and Development Final Report, CRADA Number CRD-07-259

    SciTech Connect

    Kramer, W.

    2011-10-01

    This agreement allowed NREL to serve as an advisor on SolarTAC - a collaborative effort between Xcel Energy, NREL, and the University of Colorado at Boulder. The collaboration was formed to accelerate pre-commercial and early commercial solar energy technologies to the marketplace. Through this CRADA, NREL participated in the deployment of solar energy generation technologies and related solar equipment for research, testing, validation, and demonstration purposes.

  13. Investigation of the effects of transcranial alternating current stimulation (tACS) on self-paced rhythmic movements.

    PubMed

    Varlet, Manuel; Wade, Alanna; Novembre, Giacomo; Keller, Peter E

    2017-03-18

    Human rhythmic movements spontaneously entrain to external rhythmic stimuli. Such sensory-motor entrainment can attract movements to different tempi and enhance their efficiency, with potential clinical applications for motor rehabilitation. Here we investigate whether entrainment of self-paced rhythmic movements can be induced via transcranial alternating current stimulation (tACS), which uses alternating currents to entrain spontaneous brain oscillations at specific frequencies. Participants swung a handheld pendulum at their preferred tempo with the right hand while tACS was applied over their left or right primary motor cortex at frequencies equal to their preferred tempo (Experiment 1) or in the alpha (10Hz) and beta (20Hz) ranges (Experiment 2). Given that entrainment generally occurs only if the frequency difference between two rhythms is small, stimulations were delivered at frequencies equal to participants' preferred movement tempo (≈1Hz) and ±12.5% in Experiment 1, and at 10Hz and 20Hz, and ±12.5% in Experiment 2. The comparison of participants' movement frequency, amplitude, variability, and phase synchrony with and without tACS failed to reveal entrainment or movement modifications across the two experiments. However, significant differences in stimulation-related side effects reported by participants were found between the two experiments, with phosphenes and burning sensations principally occurring in Experiment 2, and metallic tastes reported marginally more often in Experiment 1. Although other stimulation protocols may be effective, our results suggest that rhythmic movements such as pendulum swinging or locomotion that are low in goal-directedness and/or strongly driven by peripheral and mechanical constraints may not be susceptible to modulation by tACS.

  14. Anti-biofilm activity of pseudoalteromonas haloplanktis tac125 against staphylococcus epidermidis biofilm: Evidence of a signal molecule involvement?

    PubMed

    Parrilli, E; Papa, R; Carillo, S; Tilotta, M; Casillo, A; Sannino, F; Cellini, A; Artini, M; Selan, L; Corsaro, M M; Tutino, M L

    2015-03-01

    Staphylococcus epidermidis is recognized as cause of biofilm-associated infections and interest in the development of new approaches for S. epidermidis biofilm treatment has increased. In a previous paper we reported that the supernatant of Antarctic bacterium Pseudoalteromonas haloplanktis TAC125 presents an anti-biofilm activity against S. epidermidis and preliminary physico-chemical characterization of the supernatant suggested that this activity is due to a polysaccharide. In this work we further investigated the chemical nature of the anti-biofilm P. haloplanktis TAC125 molecule. The production of the molecule was evaluated in different conditions, and reported data demonstrated that it is produced in all P. haloplanktis TAC125 biofilm growth stages, also in minimal medium and at different temperatures. By using a surface coating assay, the surfactant nature of the anti-biofilm compound was excluded. Moreover, a purification procedure was set up and the analysis of an enriched fraction demonstrated that the anti-biofilm activity is not due to a polysaccharide molecule but that it is due to small hydrophobic molecules that likely work as signal. The enriched fraction was also used to evaluate the effect on S. epidermidis biofilm formation in dynamic condition by BioFlux system.

  15. TAC-Cell inputs to human hand and lip induce short-term adaptation of the primary somatosensory cortex.

    PubMed

    Venkatesan, Lalit; Barlow, Steven; Popescu, Mihai; Popescu, Anda; Auer, Edward T

    2010-08-12

    A new pneumatic tactile stimulator, called the TAC-Cell, was developed in our laboratory to non-invasively deliver patterned cutaneous stimulation to the face and hand in order to study the neuromagnetic response adaptation patterns within the primary somatosensory cortex (S1) in young adult humans. Individual TAC-Cells were positioned on the glabrous surface of the right hand, and midline of the upper and lower lip vermilion. A 151-channel magnetoencephalography (MEG) scanner was used to record the cortical response to a novel tactile stimulus which consisted of a repeating 6-pulse train delivered at three different frequencies through the active membrane surface of the TAC-Cell. The evoked activity in S1 (contralateral for hand stimulation, and bilateral for lip stimulation) was characterized from the best-fit dipoles of the earliest prominent response component. The S1 responses manifested significant modulation and adaptation as a function of the frequency of the punctate pneumatic stimulus trains and stimulus site (glabrous lip versus glabrous hand).

  16. Effect of small particle sizes on the measured density of nanocrystalline powders of nonstoichiometric tantalum carbide TaC y

    NASA Astrophysics Data System (ADS)

    Kurlov, A. S.; Gusev, A. I.

    2016-08-01

    Nanocrystalline powders of the nonstoichiometric tantalum carbide TaC y (0.81 ≤ y ≤ 0.96) with an average particle size in the range from 45 to 20 nm have been prepared using high-energy ball milling of coarse-grained powders. The density of the initial coarse-grained and prepared nanocrystalline powders of TaC y has been measured by helium pycnometry. The sizes of particles in tantalum carbide powders have been estimated using the X-ray diffraction analysis and the Brunauer-Emmett-Teller (BET) method. The density of TaC y nanopowders measured by helium pycnometry is underestimated as compared to the true density due to the adsorption of helium by the highly developed surface of the nanocrystalline powders. It has been shown that the difference between the true and measured densities is proportional to the specific surface area or is inversely proportional to the average particle size of the nanopowders. The large difference between the true and measured pycnometric densities indicates a superhydrophobicity of the tantalum carbide nanopowders.

  17. The Effect of TaC Reinforcement on the Oxidation Resistance of CNTs/SiC CMCs

    NASA Astrophysics Data System (ADS)

    Xie, Qiaoyun; Wosu, Sylvanus N.

    2016-03-01

    This study focuses on a two-stage spark plasma sintering (SPS) of TaC and/or carbon nanotubes (CNTs)-reinforced SiC ceramic matrix composites (CMCs). The oxidation mechanism of SiC-based CMCs with CNTs reinforcement as well as the TaC additives effect on the thermal oxidation resistance of the SiC-CNTs-TaC systems are investigated. The oxidation behavior up to 1500 °C is characterized in terms of mass changes, oxide layer formation, and thickness. The results showed that more disorder occurred in the CNT network with increased oxidation temperature. TaC additives exhibited an enhanced protective effect in increasing the oxidation temperature of CNTs from 460 to 550 °C, and this protective effect was effective at 1200 °C achieved by the crystalized Ta2O5 which grew with a preferred orientation giving rise to the phase separation in the glassy protective layer. Degraded oxidation resistance was found at 1500 °C.

  18. Two-dimensional TaC nanosheets on a reduced graphene oxide hybrid as an efficient and stable electrocatalyst for water splitting.

    PubMed

    He, Chunyong; Tao, Juzhou

    2016-07-07

    A novel highly active and stable HER catalyst containing two-dimensional TaC nanosheets hybridized with reduced graphene oxide (2D TaC-RGO) was prepared as an efficient and stable hydrogen evolution reaction catalyst.

  19. PERITONEAL ABSORPTION

    PubMed Central

    Hahn, P. F.; Miller, L. L.; Robscheit-Robbins, F. S.; Bale, W. F.; Whipple, G. H.

    1944-01-01

    The absorption of red cells from the normal peritoneum of the dog can be demonstrated by means of red cells labeled with radio-iron incorporated in the hemoglobin of these red cells. Absorption in normal dogs runs from 20 to 100 per cent of the amount given within 24 hours. Dogs rendered anemic by bleeding absorb red cells a little less rapidly—ranging from 5 to 80 per cent of the injected red cells. Doubly depleted dogs (anemic and hypoproteinemic) absorb even less in the three experiments recorded. This peritoneal absorption varies widely in different dogs and even in the same dog at different times. We do not know the factors responsible for these variations but there is no question about active peritoneal absorption. The intact red cells pass readily from the peritoneal cavity into lymph spaces in diaphragm and other areas of the peritoneum. The red cells move along the lymphatics and through the lymph glands with little or no phagocytosis and eventually into the large veins through the thoracic ducts. PMID:19871404

  20. Nutrient absorption.

    PubMed

    Rubin, Deborah C

    2004-03-01

    Our understanding of nutrient absorption continues to grow, from the development of unique animal models and from studies in which cutting-edge molecular and cellular biologic approaches have been used to analyze the structure and function of relevant molecules. Studies of the molecular genetics of inherited disorders have also provided many new insights into these processes. A major advance in lipid absorption has been the cloning and characterization of several intestinal acyl CoA:monoacylglycerol acyltransferases; these may provide new targets for antiobesity drug therapy. Studies of intestinal cholesterol absorption and reverse cholesterol transport have encouraged the development of novel potential treatments for hyperlipidemia. Observations in genetically modified mice and in humans with mutations in glucose transporter 2 suggest the importance of a separate microsomal membrane transport pathway for glucose transport. The study of iron metabolism has advanced greatly with the identification of the hemochromatosis gene and the continued examination of the genetic regulation of iron absorptive pathways. Several human thiamine transporters have been identified, and their specific roles in different tissues are being explored.

  1. Response of the D0 calorimeter to cosmic ray muons

    SciTech Connect

    Kotcher, J.

    1992-10-01

    The D0 Detector at the Fermi National Accelerator Laboratory is a large multipurpose detector facility designed for the study of proton-antiproton collision products at the center-of-mass energy of 2 TeV. It consists of an inner tracking volume, hermetic uranium/liquid argon sampling calorimetry, and an outer 47{pi} muon detector. In preparation for our first collider run, the collaboration organized a Cosmic Ray Commissioning Run, which took place from February--May of 1991. This thesis is a detailed study of the response of the central calorimeter to cosmic ray muons as extracted from data collected during this run. We have compared the shapes of the experimentally-obtained pulse height spectra to the Landau prediction for the ionization loss in a continuous thin absorber in the four electromagnetic and four hadronic layers of the calorimeter, and find good agreement after experimental effects are folded in. We have also determined an absolute energy calibration using two independent methods: one which measures the response of the electronics to a known amount of charge injected at the preamplifiers, and one which uses a carry-over of the calibration from a beam test of central calorimeter modules. Both absolute energy conversion factors agree with one another, within their errors. The calibration determined from the test beam carryover, relevant for use with collider physics data, has an error of 2.3%. We believe that, with further study, a final error of {approx}1% will be achieved. The theory-to-experiment comparison of the peaks (or most probable values) of the muon spectra was used to determine the layer-to-layer consistency of the muon signal. We find that the mean response in the 3 fine hadronic layers is (12 {plus_minus} 2%) higher than that in the 4 electromagnetic layers. These same comparisons have been used to verify the absolute energy conversion factors. The conversion factors work well for the electromagnetic sections.

  2. Calorimeter and related calculations for the Superconducting Super Collider

    SciTech Connect

    Gabriel, T.A.

    1989-02-01

    There are four topics to be covered in this paper. The first topic deals with the programs, the models, and the cross sections in the CALOR code package. Secondly, a discussion on compensating calorimetry as it applies to Fe/Si and U/Si calorimetry will be given. Thirdly, calculated results obtained on U/Si calorimeters using the CALOR system will be presented and discussed. Finally, the calculations that the Oak Ridge National Laboratory are carrying out dealing with radiation damage at the proposed Superconducting Super Collider (SSC) are described. 23 refs., 9 figs.

  3. Simulation of Energy Response of the ATIC Calorimeter

    NASA Technical Reports Server (NTRS)

    Batkov, K. E.; Adams, J. H., Jr.; Ahn, H. S.; Bashindzhagyan, G. L.; Case, G.; Christl, M.; Chang, J.; Fazely, A. R.; Ganel, O.; Granger, D.; Six, N. Frank (Technical Monitor)

    2002-01-01

    ATIC (Advanced Thin Ionization Calorimeter) is a balloon borne experiment designed to measure the cosmic ray composition for elements from hydrogen to iron and their energy spectra from approx.50 GeV to near 100 TeV. It consists of a Si-matrix detector to determine the charge of a CR particle, a scintillator hodoscope for tracking, carbon interaction targets and a fully active BGO calorimeter. ATIC had its first flight from McMurdo, Antarctica from 28/12/2000 to 13/01/2001. The ATIC flight collected approximately 25 million events. For reconstruction of primary spectra from spectra of energy deposits measured in the experiment, correlations between kinetic energy of a primary particle E(sub kin) and energy deposit in the calorimeter E(sub d) should be known. For this purpose, simulations of energy response of the calorimeter on energy spectra of different nuclei were done. The simulations were performed by GEANT-3.21 code with QGSM generator for nucleus - nucleus interactions. The incident flux was taken as isotropic in the ATIC aperture. Primary spectra power-law by momentum were used as inputs according to standard models of cosmic ray acceleration. These spectra become power-law by kinetic energy at E(sub kin) higher than approx.20Mc(sup 2), where M is primary nucleus mass. It should be noted that energy deposit spectra measured by ATIC illustrate similar behavior. Distributions of ratio E(sub kin)/E(sub d) are presented for different energy deposits and for a set of primaries. For power-law regions of energy spectra at E(sub d)> or equal to 20Mc(sup 2) the obtained mean value of E(sub kin)/E(sub d) increases from approx.2.4 for protons to approx.3.1 for iron, while rms/ decreases from 50% for protons to about 15% for iron. These values were obtained for the spectral index gamma=1.6

  4. Response of the D0 calorimeter to cosmic ray muons

    SciTech Connect

    Kotcher, J.

    1992-10-01

    The D0 Detector at the Fermi National Accelerator Laboratory is a large multi-purpose detector facility designed for the study of proton-antiproton collision products at the center-of-mass energy of 2 TeV. It consists of an inner tracking volume, hermetic uranium/liquid argon sampling calorimetry, and an outer 4{pi} muon detector. In preparation for our first collider run, the collaboration organized a Cosmic Ray Commissioning Run, which took place from February - May of 1991. This thesis is a detailed study of the response of the central calorimeter to cosmic ray muons as extracted from data collected during this run.

  5. Performance of the Advanced Thin Ionization Calorimeter (ATIC)

    NASA Technical Reports Server (NTRS)

    Case, G.; Ellison, S.; Gould, R.; Granger, D.; Guzik, T. G.; Isbert, J.; Price, B.; Stewart, M.; Wefel, J. P.; Adams, J. H.; Rose, M. Franklin (Technical Monitor)

    2001-01-01

    The ATIC instrument is a balloon-borne experiment capable of measuring cosmic ray elemental spectra from 50 GeV to 100 TeV for nuclei from H to Fe with a fully active Bismuth Germanate calorimeter. Several Long Duration Balloon flights from McMurdo station, Antarctica are scheduled. The detector was tested with high energy electron, proton, and pion beams at CERN. We present results for 150 and 375 GeV protons, and 150 GeV pions and comparison with a GEANT Monte Carlo.

  6. Data acquisition system for the CALICE AHCAL calorimeter

    NASA Astrophysics Data System (ADS)

    Kvasnicka, J.

    2017-03-01

    The data acquisition system (DAQ) for a highly granular analogue hadron calorimeter (AHCAL) for the future International Linear Collider is presented. The developed DAQ chain has several stages of aggregation and scales up to 8 million channels foreseen for the AHCAL detector design. The largest aggregation device, Link Data Aggregator, has 96 HDMI connectors, four Kintex7 FPGAs and a central Zynq System-On-Chip. Architecture and performance results are shown in detail. Experience from DESY testbeams with a small detector prototype consisting of 15 detector layers are shown.

  7. Analysis of diagnostic calorimeter data by the transfer function technique

    SciTech Connect

    Delogu, R. S. Pimazzoni, A.; Serianni, G.; Poggi, C.; Rossi, G.

    2016-02-15

    This paper describes the analysis procedure applied to the thermal measurements on the rear side of a carbon fibre composite calorimeter with the purpose of reconstructing the energy flux due to an ion beam colliding on the front side. The method is based on the transfer function technique and allows a fast analysis by means of the fast Fourier transform algorithm. Its efficacy has been tested both on simulated and measured temperature profiles: in all cases, the energy flux features are well reproduced and beamlets are well resolved. Limits and restrictions of the method are also discussed, providing strategies to handle issues related to signal noise and digital processing.

  8. Design and development of the SDC barrel electromagnetic calorimeter

    SciTech Connect

    Ambats, I.; Balka, L.; Blair, R.

    1994-04-01

    In fulfillment of contract SSC92-W-17743, Argonne National Laboratory is required to closeout and document all work performed in the design and development of the central calorimeter for the Solenoidal Detector Collaboration (SDC) Detector at the Superconducting Super Collider Laboratory (SSCL). This report will summarize the work performed, and identify all documents (technical reports, memo`s, drawings, etc.) that resulted from that effort. The work under this contract was shared in collaboration with the Westinghouse Science and Technology Center (WSTC) of Pittsburgh, Pennsylvania. It is the intent of this report to provide information that can be useful in the development of future detectors for high energy physics particle research.

  9. Silicon photomultiplier characterization for the GlueX barrel calorimeter

    SciTech Connect

    F. Barbosa, J.E. McKisson, J. McKisson, Y. Qiang, E. Smith, C. Zorn

    2012-12-01

    GlueX is a new detector being constructed at Jefferson Laboratory to study gluonic excitations and confinement via the detection of exotic meson states. The hermetic detector includes a barrel calorimeter where the photodetectors must operate in a high magnetic field exceeding 0.5 T. After extensive tests with a variety of sensors, the chosen photodetector will be a custom silicon photomultiplier (SiPM) array manufactured by Hamamatsu Corporation. This paper will focus on the characterization of the first 80 production samples of these SiPMs, including dark rate, photodetection efficiency (PDE), crosstalk, response uniformity and radiation tolerance.

  10. In vitro selective depletion of CD4(+)CD25(+) regulatory T-cells from PBMC using anti-tac-SAP.

    PubMed

    Akbari, Akbar; Rezaei, Abbas

    2012-01-01

    It has been shown that naturally occurring regulatory T-cells (CD4(+)CD25(+) Foxp3(+) T-cells) have critical roles in tumor invasion and down-regulation of immune response against established tumors. High expression of CD25 (IL-2Rα) by regulatory T (T(reg)) cells may cause an inefficient response when using IL-2-based cancer vaccines. It seems that selective elimination of T(reg) cells before treatment of tumor-bearing T-cells can strongly increase the efficacy of a vaccine. The aim of this study was to set up an efficient cost-effective protocol to eliminate CD4(+)CD25(+) T-cells-using the immunotoxin anti-tac-SAP. Peripheral blood mononuclear cells (PBMC) taken from colon cancer patients were treated with different concentrations (i.e., 0-100 µg/dl) of the immunotoxin. Flow cytometric analyses were then preformed to analyze expression of CD4, CD25, CD3, CD8, and CD45 surface markers; semi-quantitative fluorescent-PCR was used for the detection of Foxp3 expression before and after anti-tac-SAP treatment. The results indicated that anti-tac-SAP effectively eliminated CD4(+)CD25(+) T(reg) cells and that 25 µg/dl was the optimal concentration of anti-tac-SAP for selective depletion of these cells. These outcomes were verified by analyses of Foxp3 expression. The results also indicated that this immunotoxin had no non-specific effects on other T-cells, including CD4(+)CD25(-) and CD8(+)CD45(+) T-cells. Building on the work here, ongoing/future studies with the anti-tac-SAP will focus on functional assessments of the remaining (i.e., non-eliminated) T-cells (i.e., CD8, CD4; using proliferation and peptide sensitization assays) to ascertain if the immunotoxin inadvertently alters the functions of these cells-an untoward outcome.

  11. Calorimeter measures high nuclear heating rates and their gradients across a reactor test hole

    NASA Technical Reports Server (NTRS)

    Burwell, D.; Coombe, J. R.; Mc Bride, J.

    1970-01-01

    Pedestal-type calorimeter measures gamma-ray heating rates from 0.5 to 7.0 watts per gram of aluminum. Nuclear heating rate is a function of cylinder temperature change, measured by four chromel-alumel thermocouples attached to the calorimeter, and known thermoconductivity of the tested material.

  12. Studies of hadron-electron separators for the ZEUS barrel calorimeter

    SciTech Connect

    Ambats, I.; Bortz, D.; Connolly, A.

    1995-05-25

    Two possible upgrades, a shower maximum detector and a presampler, designed to improve the low energy electron/hadron separation capabilities of the ZEUS barrel calorimeter are described and test-beam results are reported. The presampler can also be used to correct for energy loss of particles traversing the dead material in front of the calorimeter.

  13. Test and evaluation of an Argonne National Laboratory bulk assay calorimeter

    SciTech Connect

    Rodenburg, W.W.; Fellers, C.L.; Lemming, J.F.

    1981-06-30

    The Argonne National Laboratory bulk assay calorimeter (BAC) was subjected to a series of tests, using plutonium-238 heat standards, to evaluate the performance of the calorimeter over its operating range. The results of these tests provide baseline information of the instrument performance under laboratory conditions.

  14. Twin solution calorimeter determines heats of formation of alloys at high temperatures

    NASA Technical Reports Server (NTRS)

    Darby, J. B., Jr.; Kleb, R.; Kleppa, O. J.

    1968-01-01

    Calvert-type, twin liquid metal solution calorimeter determines the heats of formation of transition metal alloys at high temperatures. The twin differential calorimeter measures the small heat effects generated over extended periods of time, has maximum operating temperature of 1073 degrees K and an automatic data recording system.

  15. Reliability of Autism-Tics, AD/HD, and other Comorbidities (A-TAC) inventory in a test-retest design.

    PubMed

    Larson, Tomas; Kerekes, Nóra; Selinus, Eva Norén; Lichtenstein, Paul; Gumpert, Clara Hellner; Anckarsäter, Henrik; Nilsson, Thomas; Lundström, Sebastian

    2014-02-01

    The Autism-Tics, AD/HD, and other Comorbidities (A-TAC) inventory is used in epidemiological research to assess neurodevelopmental problems and coexisting conditions. Although the A-TAC has been applied in various populations, data on retest reliability are limited. The objective of the present study was to present additional reliability data. The A-TAC was administered by lay assessors and was completed on two occasions by parents of 400 individual twins, with an average interval of 70 days between test sessions. Intra- and inter-rater reliability were analysed with intraclass correlations and Cohen's kappa. A-TAC showed excellent test-retest intraclass correlations for both autism spectrum disorder and attention deficit hyperactivity disorder (each at .84). Most modules in the A-TAC had intra- and inter-rater reliability intraclass correlation coefficients of > or = .60. Cohen's kappa indi- cated acceptable reliability. The current study provides statistical evidence that the A-TAC yields good test-retest reliability in a population-based cohort of children.

  16. Role of I-TAC-binding receptors CXCR3 and CXCR7 in proliferation, activation of intracellular signaling pathways and migration of various tumor cell lines.

    PubMed

    Miekus, Katarzyna; Jarocha, Danuta; Trzyna, Elzbieta; Majka, Marcin

    2010-01-01

    Chemokines and its receptors stimulate tumor growth, migration and invasion. In this study we evaluated the expression and function of CXCR3 and CXCR7 receptors in cervical carcinoma, rhabdomyosarcoma and glioblastoma cell lines. We found that both receptors were expressed at different degree by tumor cells. CXCR7 was expressed at both mRNA and protein level by all tumor cell lines. The expression of CXCR7 differed between rhabdomyosarcoma subtypes. The receptor was highly expressed in alveolar rhabdomyosarcoma and the expression was low in embryonal rhabdomyosarcoma. The expression of CXCR3 was low in majority of the tumor cell lines. Upon I-TAC stimulation AKT and MAPK kinases were activated. However, the activation of growth promoting pathways did not increased the proliferation rate of tumor cells. Since chemokines stimulate the migration of various cell types the ability of I-TAC to stimulate migration of tumor cells were studied. We did not observe the migration of tumor cells toward I-TAC gradient alone. However, at the low dose, I-TAC sensitized tumor cells toward SDF-1beta gradient and synergized with SDF-1beta in activation of intracellular pathways. Our data suggest an important role of I-TAC and its receptors in biology of solid tumors and we postulate that I-TAC-binding receptors might be used as the potential targets for antitumor therapy.

  17. The National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC): Results from Phase I and Scientific Opportunities in Phase II

    PubMed Central

    Kroner, Barbara L.; Tolunay, H. Eser; Basson, Craig T.; Pyeritz, Reed E.; Holmes, Kathryn; Maslen, Cheryl L.; Milewicz, Dianna M.; LeMaire, Scott A.; Hendershot, Tabitha; Desvigne-Nickens, Patrice; Devereux, Richard B.; Dietz, Harry C.; Song, Howard; Ringer, Danny; Mitchell, Megan; Weinsaft, Jonathan W.; Ravekes, William; Menashe, Victor; Eagle, Kim A.

    2011-01-01

    Background Genetically triggered thoracic aortic conditions (GenTAC) represent an important problem for patients and their families. Accordingly, the National Heart, Lung and Blood Institute (NHLBI) established the first phase of its national GenTAC Registry in 2006. Enrollment and Diagnoses Between 2007 and 2010, six enrolling centers established the GenTAC I Registry consisting of 2,046 patients [(Marfan syndrome 576 (28.2%); bicuspid aortic valve disease 504 (24.6%), aneurysm or dissection age <50 years 369 (18%), and others.] Biologic samples for DNA analyses (WBC’s or saliva) are available in 97% and stored plasma is available in 60% of enrollees. Results Initial scientific inquiry using the GenTAC Registry has included validation studies of genetic causes for aortic syndromes, potential usefulness of TGFB blood levels in Marfan subjects, and current surgical approaches to ascending aortic conditions. Future Opportunity GenTAC II will allow biannual follow-up of GenTAC I enrollees for up to nine years, enrollment of an additional 1,500 subjects, further integration of imaging findings with clinical and genetic data through utilization of an imaging core lab, important validation of phenotype-genotype correlations through a phenotyping core lab, and integration of a scientific advisory committee to help define the full range and depth of the Registry’s scientific capabilities. The registry resources are available to the external scientific community through an application process accessible at https://gentac.rti.org. PMID:21982653

  18. Measured Whole-House Performance of TaC Studios Test Home

    SciTech Connect

    Butler, T.; Curtis, O.; Stephenson, R.

    2013-12-01

    As part of the NAHB Research Center Industry Partnership, Southface partnered with TaC Studios, an Atlanta-based architecture firm specializing in residential and light commercial design, on the construction of a new test home in Atlanta, GA in the mixed humid climate. This home serves as a residence and home office for the firm's owners, as well as a demonstration of their design approach topotential and current clients. Southface believes the home demonstrates current best practices for the mixed-humid climate, including a building envelope featuring advanced air sealing details and low density spray foam insulation, glazing that exceeds ENERGY STAR requirements, and a high performance heating and cooling system. Construction quality and execution was a high priority for TaCStudios and was ensured by a third party review process. Post-construction testing showed that the project met stated goals for envelope performance, an air infiltration rate of 2.15 ACH50. The homeowners wished to further validate whole house energy savings through the project's involvement with Building America and this long-term monitoring effort. As a Building America test home, this homewas evaluated to detail whole house energy use, end use loads, and the efficiency and operation of the ground source heat pump and associated systems. Given that the home includes many non-typical end use loads including a home office, pool, landscape water feature, and other luxury features not accounted for in Building America modeling tools, these end uses were separately monitored todetermine their impact on overall energy consumption.

  19. Advanced order management in ERM systems: the tic-tac-toe algorithm

    NASA Astrophysics Data System (ADS)

    Badell, Mariana; Fernandez, Elena; Puigjaner, Luis

    2000-10-01

    The concept behind improved enterprise resource planning systems (ERP) systems is the overall integration of the whole enterprise functionality into the management systems through financial links. Converting current software into real management decision tools requires crucial changes in the current approach to ERP systems. This evolution must be able to incorporate the technological achievements both properly and in time. The exploitation phase of plants needs an open web-based environment for collaborative business-engineering with on-line schedulers. Today's short lifecycles of products and processes require sharp and finely tuned management actions that must be guided by scheduling tools. Additionally, such actions must be able to keep track of money movements related to supply chain events. Thus, the necessary outputs require financial-production integration at the scheduling level as proposed in the new approach of enterprise management systems (ERM). Within this framework, the economical analysis of the due date policy and its optimization become essential to manage dynamically realistic and optimal delivery dates with price-time trade-off during the marketing activities. In this work we propose a scheduling tool with web-based interface conducted by autonomous agents when precise economic information relative to plant and business actions and their effects are provided. It aims to attain a better arrangement of the marketing and production events in order to face the bid/bargain process during e-commerce. Additionally, management systems require real time execution and an efficient transaction-oriented approach capable to dynamically adopt realistic and optimal actions to support marketing management. To this end the TicTacToe algorithm provides sequence optimization with acceptable tolerances in realistic time.

  20. Radiation hardness of plastic scintillators for the Tile Calorimeter of the ATLAS detector

    NASA Astrophysics Data System (ADS)

    Jivan, H.; Mellado, B.; Sideras-Haddad, E.; Erasmus, R.; Liao, S.; Madhuku, M.; Peters, G.; Solvyanov, O.

    2015-06-01

    The radiation damage in polyvinyl toluene based plastic scintillator EJ200 obtained from ELJEN technology was investigated. This forms part of a comparative study conducted to aid in the upgrade of the Tile Calorimeter of the ATLAS detector during which the Gap scintillators will be replaced. Samples subjected to 6 MeV proton irradiation using the tandem accelerator of iThemba LABS, were irradiated with doses of approximately 0.8 MGy, 8 MGy, 25 MGy and 80 MGy. The optical properties were investigated using transmission spectroscopy whilst structural damage was assessed using Raman spectroscopy. Findings indicate that for the dose of 0.8 MGy, no structural damage occurs but a breakdown in the light transfer between base and fluor dopants is observed. For doses of 8 MGy to 80 MGy, structural damage leads to hydrogen loss in the benzene ring of the PVT base which forms free radicals. This results in an additional absorptive component causing increased transmission loss as dose is increased.

  1. Radiation hardness of plastic scintillators for the Tile Calorimeter of the ATLAS detector

    NASA Astrophysics Data System (ADS)

    Jivan, H.; Sideras-Haddad, E.; Erasmus, R.; Liao, S.; Madhuku, M.; Peters, G.; Sekonya, K.; Solvyanov, O.

    2015-10-01

    The radiation damage in polyvinyl toluene based plastic scintillator EJ200 obtained from ELJEN technology was investigated. This forms part of a comparative study conducted to aid in the upgrade of the Tile Calorimeter of the ATLAS detector during which the Gap scintillators will be replaced. Samples subjected to 6 MeV proton irradiation using the tandem accelerator of iThemba LABS, were irradiated with doses of approximately 0.8 MGy, 8 MGy, 25 MGy and 80 MGy. The optical properties were investigated using transmission spectroscopy and light yield analysis whilst structural damage was assessed using Raman spectroscopy. Findings indicate that for the dose of 0.8 MGy, no structural damage occurs and light loss can be attributed to a breakdown in the light transfer between base and fluor dopants. For doses of 8 MGy to 80 MGy, structural damage leads to possible hydrogen loss in the benzene ring of the PVT base which forms free radicals. This results in an additional absorptive component causing increased transmission loss and light yield loss with increasing dose.

  2. Computer-interfaced low-temperature, high-pressure flow calorimeter

    NASA Astrophysics Data System (ADS)

    Gopal, P.; Zollweg, J. A.; Streett, W. B.

    1989-08-01

    A flow calorimeter suitable for the measurement of heats-of-mixing of liquefied gas binaries is described. The calorimeter may be operated at temperatures between 77 and 300 K and at pressures up to 15 MPa. Endothermic energy effects are measured with a precision of (1.5 J/mol±1.2% HM ). The apparatus incorporates flow meters that measure mass flow rates directly. A computer data-acquisition system facilitates rapid measurements, a single heat-of-mixing measurement requiring less than 20 min. The calorimeter was tested by measuring the heat-of-mixing for the nitrogen-argon system. The calorimeter is an improvement on previous low-temperature flow calorimeters in both accuracy and speed of measurement.

  3. Construction of a hadron calorimeter for Jefferson Lab Hall-A Super Bigbite Spectrometer

    NASA Astrophysics Data System (ADS)

    Mamyan, Vahe

    2015-04-01

    A ``shashlik'' hadron calorimeter is being constructed for the new Super Bigbite Spectrometer in Jefferson Lab Hall-A. The calorimeter will be used in nucleon-coincidence form-factor experiments taking advantage of Jefferson Labs' 12 GeV upgrade. An adiabatic light guide has been developed for the calorimeter based on laser cut acrylic sheets. A prototype module has been built to measure time resolution of the calorimeter for cosmic ray muons as well as to validate the Geant4 simulation. Several innovations in the calorimeter design will be discussed, in particular the choice of the scintillator, wave length shifter and the construction process of the light. The results of prototype tests is compared with Geant4 simulation for cosmic ray muons and prediction of HCal time and special resolution for hadrons in the 2-10 GeV/c momentum range will be presented. SBS COLLABORATION.

  4. Cryogenic Tests of the ATLAS Liquid Argon Calorimeter

    NASA Astrophysics Data System (ADS)

    Bremer, J.; Chalifour, M.; Fabre, C.; Gonidec, A.; Passardi, G.

    2006-04-01

    The ATLAS liquid argon calorimeter consists of the barrel and two end-cap detectors housed in three independent cryostats filled with a total volume of 78 m3 of liquid argon. During cool-down the temperature differences in the composite structure of the detectors must be kept within strict limits to avoid excessive mechanical stresses and relative displacements. During normal operation the formation of gas bubbles, which are detrimental to the functioning of the detector, must be prevented and temperature gradients of less than 0.7 K across the argon bath are mandatory due to the temperature dependence of the energy measurements. Between April 2004 and May 2005 the barrel (120 t) and one end-cap (219 t) underwent qualification tests at the operating temperature of 87.3 K using a dedicated test facility at ground level. These tests provided a validation of the cooling methods to be adopted in the final underground configuration. In total 6.9 GJ and 15.7 GJ were extracted from the calorimeters and a temperature uniformity of the argon bath of less than 0.4 K was achieved.

  5. LED Monitoring System of the Phenix Muon Piston Calorimeter

    NASA Astrophysics Data System (ADS)

    Motschwiller, Steven

    2010-11-01

    The Muon Piston Calorimeter in the PHENIX experiment at RHIC has a monitoring system consisting of LEDs and PIN diodes to calibrate out the time dependent changes to the detector. The LEDs track the temperature and radiation-damage changes to the response of the MPC, while the absolute calibration can be done using 0̂ decays. To execute this, LEDs flash light through the PbWO4 crystal to the Avalanche Photo Diodes The MPC is made up of 416 independent electromagnetic calorimeter towers. By using the LEDs we can correct for changes in the gains of each tower in the MPC, on a run by run basis. Because the LED value only gives a relative measurement of the gain over time, this method of calibration can only be used in conjunction with absolute calibrations provided by 0̂ decays or by minimum ionizing peaks . This work will be used to make a final measurement on Transverse energy at √sNN = 200 GV in Au+Au collisions.

  6. Calibration and Monitoring of the CMS Electromagnetic Calorimeter

    NASA Astrophysics Data System (ADS)

    La Licata, C.

    2014-06-01

    The CMS Electromagnetic Calorimeter (ECAL) is a homogeneous and hermetic calorimeter with high granularity and fast response, designed to provide high resolution measurements of electron and photon energy. Precise calibration of the ECAL must be performed in situ at the LHC, in order to achieve and maintain its design performance and to fully exploit the physics reach of CMS. Several techniques have been developed for the intercalibration of ECAL using collision data. These methods are based on the reconstruction of the invariant mass peak of unconverted photons from low mass particle decays (π0and η) and on the azimuthal symmetry of the average energy deposition at a given pseudorapidity. Further intercalibration is carried out by using isolated electrons from W and Z bosons decays to compare the energy measured in ECAL to the momentum of the reconstructed tracks. The absolute calibration of the energy scale is performed using Z decays into electron-positron pairs. Changes in the ECAL response due to crystal radiation damage and changes in photo-detector output must be monitored. A system based on the injection of laser light into each crystal is used to track and correct for these variations during LHC operations.

  7. Unix version of CALOR89 for calorimeter applications

    SciTech Connect

    Handler, T.; Job, P.K.; Price, L.E.; Gabriel, T.A.

    1992-05-12

    CALOR89 is a system of coupled Monte Carlo particle transport computer codes which has been successfully employed for the estimation of calorimeter parameters in High Energy Physics. In the past CALOR89 has been running on various IBM machines and on CRAY X-MP at Lawrence Livermore Lab. These machines had non-unix operating systems. In this report we present a UNIX version of CALOR89, which is especially suited for the UNIX work stations. Moreover CALOR89 is also been supplemented with two new program packages which makes it more user friendly. CALPREP is a program for the preparation of the input files for CALOR89 in general geometry and ANALYZ is an analysis package to extract the final results from CALOR89 relevant to calorimeters. This report also provides two script files LCALOR and PCALOR. LCALOR runs CALOR89 sequences of programs and EGS4 for a given configuration sequentially on a single processor and PCALOR concurrently on a multiprocessor unix workstation.

  8. New calorimeters for space experiments: physics requirements and technological challenges

    NASA Astrophysics Data System (ADS)

    Marrocchesi, Pier Simone

    2015-07-01

    Direct measurements of charged cosmic radiation with instruments in Low Earth Orbit (LEO), or flying on balloons above the atmosphere, require the identification of the incident particle, the measurement of its energy and possibly the determination of its sign-of-charge. The latter information can be provided by a magnetic spectrometer together with a measurement of momentum. However, magnetic deflection in space experiments is at present limited to values of the Maximum Detectable Rigidity (MDR) hardly exceeding a few TV. Advanced calorimetric techniques are, at present, the only way to measure charged and neutral radiation at higher energies in the multi-TeV range. Despite their mass limitation, calorimeters may achieve a large geometric factor and provide an adequate proton background rejection factor, taking advantage of a fine granularity and imaging capabilities. In this lecture, after a brief introduction on electromagnetic and hadronic calorimetry, an innovative approach to the design of a space-borne, large acceptance, homogeneous calorimeter for the detection of high energy cosmic rays will be described.

  9. Monte Carlo Simulation of Massive Absorbers for Cryogenic Calorimeters

    SciTech Connect

    Brandt, D.; Asai, M.; Brink, P.L.; Cabrera, B.; Silva, E.do Couto e; Kelsey, M.; Leman, S.W.; McArthy, K.; Resch, R.; Wright, D.; Figueroa-Feliciano, E.; /MIT

    2012-06-12

    There is a growing interest in cryogenic calorimeters with macroscopic absorbers for applications such as dark matter direct detection and rare event search experiments. The physics of energy transport in calorimeters with absorber masses exceeding several grams is made complex by the anisotropic nature of the absorber crystals as well as the changing mean free paths as phonons decay to progressively lower energies. We present a Monte Carlo model capable of simulating anisotropic phonon transport in cryogenic crystals. We have initiated the validation process and discuss the level of agreement between our simulation and experimental results reported in the literature, focusing on heat pulse propagation in germanium. The simulation framework is implemented using Geant4, a toolkit originally developed for high-energy physics Monte Carlo simulations. Geant4 has also been used for nuclear and accelerator physics, and applications in medical and space sciences. We believe that our current work may open up new avenues for applications in material science and condensed matter physics.

  10. π0 Reconstruction using the Muon Piston Calorimeter Extension

    NASA Astrophysics Data System (ADS)

    Dixit, Dhruv; Phenix Collaboration

    2015-10-01

    The Muon-Piston Calorimeter Extension (MPC-EX) is a new detector in the PHENIX experiment at the Relativistic Heavy Ion Collider that was installed for the recent Run 15 of the experiment. In polarized p+p and polarized p+A collisions, an important measurement is the yield and momentum distribution of direct photons. Unaffected by the strong force, direct photons traverse the dense medium in the collision zone mostly unchanged, thereby providing information about the initial stages of the collision. However, there is a huge background of photons from other sources, primarily π0 which decay into two photons. The opening angle between the decay photons becomes smaller with higher energies of the original π0. For energies greater than ~20 GeV, the Muon Piston Calorimeter (MPC) cannot distinguish the two decay photons from a single photon, as their showers merge. The MPC-EX, an 8-layer tungsten and silicon sensor sandwich in front of the MPC, can measure and image the shower development, and help distinguish between direct photons and π0 decay photons up to higher energies than the MPC alone. We will describe the MPC-EX detector and its readout, and present the calibration procedures applied to the data in order to obtain the π0 spectrum. This project was supported in part by the U.S. Department of Energy, Office of Science, Office of Workforce Development for Teachers and Scientists (WDTS) under the Science Undergraduate Laboratory Internships Program (SULI).

  11. Development of a semi-adiabatic isoperibol solution calorimeter

    SciTech Connect

    Venkata Krishnan, R.; Jogeswararao, G.; Parthasarathy, R.; Premalatha, S.; Prabhakar Rao, J.; Gunasekaran, G.; Ananthasivan, K.

    2014-12-15

    A semi-adiabatic isoperibol solution calorimeter has been indigenously developed. The measurement system comprises modules for sensitive temperature measurement probe, signal processing, data collection, and joule calibration. The sensitivity of the temperature measurement module was enhanced by using a sensitive thermistor coupled with a lock-in amplifier based signal processor. A microcontroller coordinates the operation and control of these modules. The latter in turn is controlled through personal computer (PC) based custom made software developed with LabView. An innovative summing amplifier concept was used to cancel out the base resistance of the thermistor. The latter was placed in the dewar. The temperature calibration was carried out with a standard platinum resistance (PT100) sensor coupled with an 8½ digit multimeter. The water equivalent of this calorimeter was determined by using electrical calibration with the joule calibrator. The experimentally measured values of the quantum of heat were validated by measuring heats of dissolution of pure KCl (for endotherm) and tris (hydroxyl methyl) amino-methane (for exotherm). The uncertainity in the measurements was found to be within ±3%.

  12. Development of a semi-adiabatic isoperibol solution calorimeter.

    PubMed

    Venkata Krishnan, R; Jogeswararao, G; Parthasarathy, R; Premalatha, S; Prabhakar Rao, J; Gunasekaran, G; Ananthasivan, K

    2014-12-01

    A semi-adiabatic isoperibol solution calorimeter has been indigenously developed. The measurement system comprises modules for sensitive temperature measurement probe, signal processing, data collection, and joule calibration. The sensitivity of the temperature measurement module was enhanced by using a sensitive thermistor coupled with a lock-in amplifier based signal processor. A microcontroller coordinates the operation and control of these modules. The latter in turn is controlled through personal computer (PC) based custom made software developed with LabView. An innovative summing amplifier concept was used to cancel out the base resistance of the thermistor. The latter was placed in the dewar. The temperature calibration was carried out with a standard platinum resistance (PT100) sensor coupled with an 8½ digit multimeter. The water equivalent of this calorimeter was determined by using electrical calibration with the joule calibrator. The experimentally measured values of the quantum of heat were validated by measuring heats of dissolution of pure KCl (for endotherm) and tris (hydroxyl methyl) amino-methane (for exotherm). The uncertainity in the measurements was found to be within ±3%.

  13. Development of a semi-adiabatic isoperibol solution calorimeter

    NASA Astrophysics Data System (ADS)

    Venkata Krishnan, R.; Jogeswararao, G.; Parthasarathy, R.; Premalatha, S.; Prabhakar Rao, J.; Gunasekaran, G.; Ananthasivan, K.

    2014-12-01

    A semi-adiabatic isoperibol solution calorimeter has been indigenously developed. The measurement system comprises modules for sensitive temperature measurement probe, signal processing, data collection, and joule calibration. The sensitivity of the temperature measurement module was enhanced by using a sensitive thermistor coupled with a lock-in amplifier based signal processor. A microcontroller coordinates the operation and control of these modules. The latter in turn is controlled through personal computer (PC) based custom made software developed with LabView. An innovative summing amplifier concept was used to cancel out the base resistance of the thermistor. The latter was placed in the dewar. The temperature calibration was carried out with a standard platinum resistance (PT100) sensor coupled with an 8½ digit multimeter. The water equivalent of this calorimeter was determined by using electrical calibration with the joule calibrator. The experimentally measured values of the quantum of heat were validated by measuring heats of dissolution of pure KCl (for endotherm) and tris (hydroxyl methyl) amino-methane (for exotherm). The uncertainity in the measurements was found to be within ±3%.

  14. Structural flexibility of the heme cavity in the cold-adapted truncated hemoglobin from the Antarctic marine bacterium Pseudoalteromonas haloplanktis TAC125.

    PubMed

    Giordano, Daniela; Pesce, Alessandra; Boechi, Leonardo; Bustamante, Juan Pablo; Caldelli, Elena; Howes, Barry D; Riccio, Alessia; di Prisco, Guido; Nardini, Marco; Estrin, Dario; Smulevich, Giulietta; Bolognesi, Martino; Verde, Cinzia

    2015-08-01

    Truncated hemoglobins build one of the three branches of the globin protein superfamily. They display a characteristic two-on-two α-helical sandwich fold and are clustered into three groups (I, II and III) based on distinct structural features. Truncated hemoglobins are present in eubacteria, cyanobacteria, protozoa and plants. Here we present a structural, spectroscopic and molecular dynamics characterization of a group-II truncated hemoglobin, encoded by the PSHAa0030 gene from Pseudoalteromonas haloplanktis TAC125 (Ph-2/2HbO), a cold-adapted Antarctic marine bacterium hosting one flavohemoglobin and three distinct truncated hemoglobins. The Ph-2/2HbO aquo-met crystal structure (at 2.21 Å resolution) shows typical features of group-II truncated hemoglobins, namely the two-on-two α-helical sandwich fold, a helix Φ preceding the proximal helix F, and a heme distal-site hydrogen-bonded network that includes water molecules and several distal-site residues, including His(58)CD1. Analysis of Ph-2/2HbO by electron paramagnetic resonance, resonance Raman and electronic absorption spectra, under varied solution conditions, shows that Ph-2/2HbO can access diverse heme ligation states. Among these, detection of a low-spin heme hexa-coordinated species suggests that residue Tyr(42)B10 can undergo large conformational changes in order to act as the sixth heme-Fe ligand. Altogether, the results show that Ph-2/2HbO maintains the general structural features of group-II truncated hemoglobins but displays enhanced conformational flexibility in the proximity of the heme cavity, a property probably related to the functional challenges, such as low temperature, high O2 concentration and low kinetic energy of molecules, experienced by organisms living in the Antarctic environment.

  15. Room-temperature calorimeter for x-ray free-electron lasers

    SciTech Connect

    Tanaka, T. Kato, M.; Saito, N.; Tono, K.; Yabashi, M.; Ishikawa, T.

    2015-09-15

    We have developed a room-temperature calorimeter for absolute radiant power measurements of x-ray free-electron lasers. This room-temperature calorimeter is an electrical substitution device based on the equivalence of electrical and radiant heating. Consequently, the measured radiant powers are traceable to electrical standards, i.e., the International System Units (SI). We demonstrated the performance of the room-temperature calorimeter by electrical power measurements (offline tests). In the offline tests, the room-temperature calorimeter was proven to be able to measure external powers up to at least 6.9 mW, which exceeds the upper limit (∼4 mW) of a cryogenic radiometer (the primary standard detector in Japan). In addition, measurement uncertainties of the room-temperature calorimeter were evaluated to be less than 1.0%, which is adequate for the radiant power measurements of x-ray free-electron lasers. An indirect comparison with the cryogenic radiometer was performed using a synchrotron radiation source to confirm the validity of the absolute radiant powers measured with the room-temperature calorimeter. The absolute radiant powers measured by the calorimeter agreed with those measured by the cryogenic radiometer within 0.6%, which is less than the relative standard uncertainty of the comparison (1.0%)

  16. Room-temperature calorimeter for x-ray free-electron lasers.

    PubMed

    Tanaka, T; Kato, M; Saito, N; Tono, K; Yabashi, M; Ishikawa, T

    2015-09-01

    We have developed a room-temperature calorimeter for absolute radiant power measurements of x-ray free-electron lasers. This room-temperature calorimeter is an electrical substitution device based on the equivalence of electrical and radiant heating. Consequently, the measured radiant powers are traceable to electrical standards, i.e., the International System Units (SI). We demonstrated the performance of the room-temperature calorimeter by electrical power measurements (offline tests). In the offline tests, the room-temperature calorimeter was proven to be able to measure external powers up to at least 6.9 mW, which exceeds the upper limit (∼4 mW) of a cryogenic radiometer (the primary standard detector in Japan). In addition, measurement uncertainties of the room-temperature calorimeter were evaluated to be less than 1.0%, which is adequate for the radiant power measurements of x-ray free-electron lasers. An indirect comparison with the cryogenic radiometer was performed using a synchrotron radiation source to confirm the validity of the absolute radiant powers measured with the room-temperature calorimeter. The absolute radiant powers measured by the calorimeter agreed with those measured by the cryogenic radiometer within 0.6%, which is less than the relative standard uncertainty of the comparison (1.0%).

  17. Room-temperature calorimeter for x-ray free-electron lasers

    NASA Astrophysics Data System (ADS)

    Tanaka, T.; Kato, M.; Saito, N.; Tono, K.; Yabashi, M.; Ishikawa, T.

    2015-09-01

    We have developed a room-temperature calorimeter for absolute radiant power measurements of x-ray free-electron lasers. This room-temperature calorimeter is an electrical substitution device based on the equivalence of electrical and radiant heating. Consequently, the measured radiant powers are traceable to electrical standards, i.e., the International System Units (SI). We demonstrated the performance of the room-temperature calorimeter by electrical power measurements (offline tests). In the offline tests, the room-temperature calorimeter was proven to be able to measure external powers up to at least 6.9 mW, which exceeds the upper limit (˜4 mW) of a cryogenic radiometer (the primary standard detector in Japan). In addition, measurement uncertainties of the room-temperature calorimeter were evaluated to be less than 1.0%, which is adequate for the radiant power measurements of x-ray free-electron lasers. An indirect comparison with the cryogenic radiometer was performed using a synchrotron radiation source to confirm the validity of the absolute radiant powers measured with the room-temperature calorimeter. The absolute radiant powers measured by the calorimeter agreed with those measured by the cryogenic radiometer within 0.6%, which is less than the relative standard uncertainty of the comparison (1.0%).

  18. Fabrication and Characterization of a Multichannel 3D Thermopile for Chip Calorimeter Applications

    PubMed Central

    Huynh, Tho Phuoc; Zhang, Yilei; Yehuda, Cohen

    2015-01-01

    Thermal sensors based on thermopiles are some of the most robust and popular temperature sensing technologies across industries and research disciplines. A chip calorimeter with a 3D thermopile layout with a large sensing area and multichannel capacity has been developed, which is highly desired for many applications requiring large reaction chambers or high throughputs, such as biofilm research, drug screening, etc. The performance of the device, including temperature sensitivity and heat power sensitivity, was evaluated. The capability to split the chip calorimeter to multiple channels was also demonstrated, which makes the chip calorimeter very flexible and powerful in many applications. PMID:25654716

  19. Beam test results of a high-granularity tile/fiber electromagnetic calorimeter

    NASA Astrophysics Data System (ADS)

    Ono, H.; Miyata, H.; Iba, S.; Nakajima, N.; Sanchez, A. L. C.; Fujii, Y.; Itoh, S.; Kajino, F.; Kanzaki, J.; Kawagoe, K.; Kim, S.; Kishimoto, S.; Matsumoto, T.; Matsunaga, H.; Nagano, A.; Nakamura, R.; Takeshita, T.; Tamura, Y.; Yamauchi, S.

    2009-03-01

    A prototype sampling electromagnetic calorimeter (17.1 radiation lengths) for future linear collider experiments was built, using 4 cm×4 cm×1 mm plastic scintillator tiles and 4 mm-thick lead absorber. Wavelength-shifting fibers were used to guide the scintillation light into multi-anode photo-multiplier tubes. The calorimeter was tested at the beam test facility of the High Energy Accelerator Research Organization (KEK) in 2004. In this article we present our beam test results for the tile/fiber calorimeter focusing on the linearity in energy response, the energy resolution, position resolution and uniformity across the tile front face.

  20. The small-angle performance of a dual-readout fiber calorimeter

    NASA Astrophysics Data System (ADS)

    Cardini, A.; Cascella, M.; Choi, S.; De Pedis, D.; Ferrari, R.; Franchino, S.; Gaudio, G.; Ha, S.; Hauptman, J.; La Rotonda, L.; Lee, S.; Li, F.; Livan, M.; Meoni, E.; Scuri, F.; Sill, A.; Wigmans, R.

    2016-02-01

    The performance of the RD52 dual-readout calorimeter is measured for very small angles of incidence between the 20 GeV electron beam particles and the direction of the fibers that form the active elements of this calorimeter. The calorimeter response is observed to be independent of the angle of incidence for both the scintillating and the Čerenkov fibers, whereas significant differences are found between the angular dependence of the energy resolution measured with these two types of fibers. The experimental results are on crucial points at variance with the predictions of GEANT4 Monte Carlo simulations.

  1. Central Calorimeter configuration: A study report to the SDC Technical Board

    SciTech Connect

    Kirk, T.B.W.; Wicklund, A.B.

    1991-04-11

    The single most important determinant of the overall Central Calorimeter (CC) shape is the criterion for depth of hadron shower containment. This criterion and its rapidity dependence is discussed in a companion document to this report titled ``Depth Requirements in SSC Calorimeters`` by a D. Green et al., SDC-91-00016. The conclusion reached there is that the calorimeter should be 10 {lambda} thick at {eta} = 0 and increase smoothly to 12 {lambda} at {eta} = 3. We adopt this criterion in this report and discuss the mechanical properties and design details of a CC that meets this condition.

  2. The design and performance of the electromagnetic calorimeters in Hall C at Jefferson Lab

    SciTech Connect

    Vardan Tadevosyan, Hamlet Mkrtchyan, Arshak Asaturyan, Arthur Mkrtchyan, Simon Zhamkochyan

    2012-12-01

    The design and performance of the electromagnetic calorimeters in the magnetic spectrometers in Hall C at Jefferson Lab are presented. For the existing HMS and SOS spectrometers, construction information and comparisons of simulated and experimental results are presented. The design and simulated performance for a new calorimeter to be used in the new SHMS spectrometer is also presented. We have developed and constructed electromagnetic calorimeters from TF-1 type lead-glass blocks for the HMS and SOS magnetic spectrometers at JLab Hall C. The HMS/SOS calorimeters are of identical design and construction except for their total size. Blocks of dimension 10 cm × 10 cm × 70 cm are arranged in four planes and stacked 13 and 11 blocks high in the HMS and SOS respectively. The energy resolution of these calorimeters is better than 6%/√E, and pion/electron (π/e) separation of about 100:1 has been achieved in energy range 1–5 GeV. Good agreement has been observed between the experimental and GEANT4 simulated energy resolutions. The HMS/SOS calorimeters have been used nearly in all Hall C experiments, providing good energy resolution and a high pion suppression factor. No significant deterioration in their performance has been observed in the course of use since 1994. For the SHMS spectrometer, presently under construction, details on the calorimeter design and accompanying GEANT4 simulation efforts are given. A Preshower+Shower design was selected as the most cost-effective among several design choices. The preshower will consist of a layer of 28 modules with TF-1 type lead glass radiators, stacked in two columns. The shower part will consist of 224 modules with F-101 type lead glass radiators, stacked in a “fly's eye” configuration of 14 columns and 16 rows. The active area of 120 × 130 cm(2) will encompass the beam envelope at the calorimeter. The anticipated performance of the new calorimeter is simulated over the full momentum range of the SHMS, predicting

  3. The upgrade of the CMS hadron calorimeter with silicon photomultipliers

    NASA Astrophysics Data System (ADS)

    Strobbe, N.

    2017-01-01

    The upgrade of the hadron calorimeter of the CMS experiment at the CERN Large Hadron Collider is currently underway. The endcap sections will be upgraded in the winter of 2016–2017 and the barrel sections during the second LHC long shutdown in 2019. The existing photosensors will be replaced with about 16 000 new silicon photomultipliers (SiPMs), resulting in the first large installation of SiPMs in a radiation environment. All associated front-end electronics will also be upgraded. This paper discusses the motivation for the upgrade and provides a description of the new system, including the SiPMs with associated control electronics and the front-end readout cards.

  4. The LYSO crystal calorimeter for the Mu2e experiment

    NASA Astrophysics Data System (ADS)

    Pezzullo, G.; Budagov, J.; Carosi, R.; Cervelli, F.; Cheng, C.; Cordelli, M.; Corradi, G.; Davydov, Yu; Echenard, B.; Giovannella, S.; Glagolev, V.; Happacher, F.; Hitlin, D.; Luca, A.; Martini, M.; Miscetti, S.; Murat, P.; Ongmonkolkul, P.; Porter, F.; Saputi, A.; Sarra, I.; Spinella, F.; Stomaci, V.; Tassielli, G.

    2014-03-01

    The Mu2e experiment at Fermilab searches the neutrino-less conversion of the muon into electron in the field of an Aluminum nucleus. If such a process will be observed, it will be a proof of the charged-lepton-flavor-violation (cLFV), otherwise Mu2e will set an upper limit of Rμe < 6 × 10-17 @ 90% C.L. (which represents an improvement by 3-4 order of magnitude over the existing limit). The Mu2e detector apparatus consists of a magnetic spectrometer, devoted to the measurement of the electrons momentum, and an electromagnetic calorimeter (EMC) which provides an independent measurement of the electron energy, time and position, used for validating or rejecting candidate tracks selected by the tracking system. In this paper, we describe the baseline project of the EMC and present results in terms of performances and R&D.

  5. A hadronic calorimeter with Glass RPC as sensitive medium

    NASA Astrophysics Data System (ADS)

    Grenier, G.

    2014-09-01

    The SDHCAL technological prototype is a 1 × 1 × 1.3 m3 high-granularity Semi-Digital Hadronic CALorimeter using Glass Resistive Plate Chambers as sensitive medium. It is one of the two HCAL options considered by the ILD Collaboration to be proposed for the detector of the future International Linear Collider project. The prototype is made of up to 50 GRPC detectors of 1 m2 size and 3 mm thickness each with an embedded semi-digital electronics readout that is autotriggering and power-pulsed. The GRPC readout is finely segmented into pads of 1 cm2. Measured performances of the GRPC and the full SDHCAL prototype in terms of homogeneity, low noise and energy resolution are presented in this proceeding.

  6. The magnetized steel and scintillator calorimeters of the MINOS experiment

    NASA Astrophysics Data System (ADS)

    Minos Collaboration; Michael, D. G.; Adamson, P.; Alexopoulos, T.; Allison, W. W. M.; Alner, G. J.; Anderson, K.; Andreopoulos, C.; Andrews, M.; Andrews, R.; Arroyo, C.; Avvakumov, S.; Ayres, D. S.; Baller, B.; Barish, B.; Barker, M. A.; Barnes, P. D.; Barr, G.; Barrett, W. L.; Beall, E.; Bechtol, K.; Becker, B. R.; Belias, A.; Bergfeld, T.; Bernstein, R. H.; Bhattacharya, D.; Bishai, M.; Blake, A.; Bocean, V.; Bock, B.; Bock, G. J.; Boehm, J.; Boehnlein, D. J.; Bogert, D.; Border, P. M.; Bower, C.; Boyd, S.; Buckley-Geer, E.; Byon-Wagner, A.; Cabrera, A.; Chapman, J. D.; Chase, T. R.; Chernichenko, S. K.; Childress, S.; Choudhary, B. C.; Cobb, J. H.; Coleman, S. J.; Cossairt, J. D.; Courant, H.; Crane, D. A.; Culling, A. J.; Damiani, D.; Dawson, J. W.; de Jong, J. K.; Demuth, D. M.; de Santo, A.; Dierckxsens, M.; Diwan, M. V.; Dorman, M.; Drake, G.; Ducar, R.; Durkin, T.; Erwin, A. R.; Escobar, C. O.; Evans, J. J.; Fackler, O. D.; Falk Harris, E.; Feldman, G. J.; Felt, N.; Fields, T. H.; Ford, R.; Frohne, M. V.; Gallagher, H. R.; Gebhard, M.; Godley, A.; Gogos, J.; Goodman, M. C.; Gornushkin, Yu.; Gouffon, P.; Grashorn, E. W.; Grossman, N.; Grudzinski, J. J.; Grzelak, K.; Guarino, V.; Habig, A.; Halsall, R.; Hanson, J.; Harris, D.; Harris, P. G.; Hartnell, J.; Hartouni, E. P.; Hatcher, R.; Heller, K.; Hill, N.; Ho, Y.; Howcroft, C.; Hylen, J.; Ignatenko, M.; Indurthy, D.; Irwin, G. M.; James, C.; Jenner, L.; Jensen, D.; Joffe-Minor, T.; Kafka, T.; Kang, H. J.; Kasahara, S. M. S.; Kilmer, J.; Kim, H.; Kim, M. S.; Koizumi, G.; Kopp, S.; Kordosky, M.; Koskinen, D. J.; Kostin, M.; Kotelnikov, S. K.; Krakauer, D. A.; Kumaratunga, S.; Ladran, A. S.; Lang, K.; Laughton, C.; Lebedev, A.; Lee, R.; Lee, W. Y.; Libkind, M. A.; Liu, J.; Litchfield, P. J.; Litchfield, R. P.; Longley, N. P.; Lucas, P.; Luebke, W.; Madani, S.; Maher, E.; Makeev, V.; Mann, W. A.; Marchionni, A.; Marino, A. D.; Marshak, M. L.; Marshall, J. S.; McDonald, J.; McGowan, A. M.; Meier, J. R.; Merzon, G. I.; Messier, M. D.; Milburn, R. H.; Miller, J. L.; Miller, W. H.; Mishra, S. R.; Miyagawa, P. S.; Moore, C. D.; Morfín, J.; Morse, R.; Mualem, L.; Mufson, S.; Murgia, S.; Murtagh, M. J.; Musser, J.; Naples, D.; Nelson, C.; Nelson, J. K.; Newman, H. B.; Nezrick, F.; Nichol, R. J.; Nicholls, T. C.; Ochoa-Ricoux, J. P.; Oliver, J.; Oliver, W. P.; Onuchin, V. A.; Osiecki, T.; Ospanov, R.; Paley, J.; Paolone, V.; Para, A.; Patzak, T.; Pavlović, Ž.; Pearce, G. F.; Pearson, N.; Peck, C. W.; Perry, C.; Peterson, E. A.; Petyt, D. A.; Ping, H.; Piteira, R.; Pla-Dalmau, A.; Plunkett, R. K.; Price, L. E.; Proga, M.; Pushka, D. R.; Rahman, D.; Rameika, R. A.; Raufer, T. M.; Read, A. L.; Rebel, B.; Reyna, D. E.; Rosenfeld, C.; Rubin, H. A.; Ruddick, K.; Ryabov, V. A.; Saakyan, R.; Sanchez, M. C.; Saoulidou, N.; Schneps, J.; Schoessow, P. V.; Schreiner, P.; Schwienhorst, R.; Semenov, V. K.; Seun, S.-M.; Shanahan, P.; Shield, P. D.; Shivane, R.; Smart, W.; Smirnitsky, V.; Smith, C.; Smith, P. N.; Sousa, A.; Speakman, B.; Stamoulis, P.; Stefanik, A.; Sullivan, P.; Swan, J. M.; Symes, P. A.; Tagg, N.; Talaga, R. L.; Terekhov, A.; Tetteh-Lartey, E.; Thomas, J.; Thompson, J.; Thomson, M. A.; Thron, J. L.; Trendler, R.; Trevor, J.; Trostin, I.; Tsarev, V. A.; Tzanakos, G.; Urheim, J.; Vahle, P.; Vakili, M.; Vaziri, K.; Velissaris, C.; Verebryusov, V.; Viren, B.; Wai, L.; Ward, C. P.; Ward, D. R.; Watabe, M.; Weber, A.; Webb, R. C.; Wehmann, A.; West, N.; White, C.; White, R. F.; Wojcicki, S. G.; Wright, D. M.; Wu, Q. K.; Yan, W. G.; Yang, T.; Yumiceva, F. X.; Yun, J. C.; Zheng, H.; Zois, M.; Zwaska, R.; MINOS Collaboration

    2008-11-01

    The Main Injector Neutrino Oscillation Search (MINOS) experiment uses an accelerator-produced neutrino beam to perform precision measurements of the neutrino oscillation parameters in the "atmospheric neutrino" sector associated with muon neutrino disappearance. This long-baseline experiment measures neutrino interactions in Fermilab's NuMI neutrino beam with a near detector at Fermilab and again 735 km downstream with a far detector in the Soudan Underground Laboratory in northern Minnesota. The two detectors are magnetized steel-scintillator tracking calorimeters. They are designed to be as similar as possible in order to ensure that differences in detector response have minimal impact on the comparisons of event rates, energy spectra and topologies that are essential to MINOS measurements of oscillation parameters. The design, construction, calibration and performance of the far and near detectors are described in this paper.

  7. A superconducting supercollider calorimeter photomultiplier tube preamplifier circuit

    NASA Astrophysics Data System (ADS)

    Panescu, Dorin; Lackey, Joe; Robl, Phil; Smith, Wesley H.

    1992-07-01

    This study presents the design of the front end amplifier for a scintillator calorimeter with photomultiplier tube (PMT) readout. The design is based on analytical computations and SPICE simulations, and is checked against tests performed on a prototyped circuit. We were looking to achieve 1) a very low droop within the 4 ns after the integration of the photomultiplier tube (PMT) signal was completed, 2) a very low noise figure for the whole amplifier in a 100 MHz bandwidth, 3) an input impedance optimized for the PMT which is actually used, 4) baseline restoration as quick as possible at the output of the clip amps. 5) no loss of information due to the saturation at intermediary stages (e.g. integrator), and 6) an output driving 100 Ω twisted pair cables, or 50 Ω coaxial cables, in order to transmit the signal to switched capacitor arrays for analog storage.

  8. Performance of the ATLAS electromagnetic calorimeter barrel module 0

    NASA Astrophysics Data System (ADS)

    Aubert, B.; Ballansat, J.; Bazan, A.; Beaugiraud, B.; Boniface, J.; Chollet, F.; Colas, J.; Delebecque, P.; di Ciaccio, L.; Dumont-Dayot, N.; El Kacimi, M.; Gaumer, O.; Ghez, P.; Girard, C.; Gouanère, M.; Kambara, H.; Jérémie, A.; Jézéquel, S.; Lafaye, R.; Leflour, T.; Le Maner, C.; Lesueur, J.; Massol, N.; Moynot, M.; Neukermans, L.; Perrodo, P.; Perrot, G.; Poggioli, L.; Prast, J.; Przysiezniak, H.; Riccadona, X.; Sauvage, G.; Thion, J.; Wingerter-Seez, I.; Zitoun, R.; Zolnierowski, Y.; Chen, H.; Citterio, M.; Farrell, J.; Gordon, H.; Hackenburg, B.; Hoffman, A.; Kierstead, J.; Lanni, F.; Leite, M.; Lissauer, D.; Ma, H.; Makowiecki, D.; Radeka, V.; Rahm, D.; Rajagopalan, S.; Rescia, S.; Stumer, I.; Takai, H.; Yip, K.; Benchekroun, D.; Driouichi, C.; Hoummada, A.; Hakimi, M.; Stroynowski, R.; Ye, J.; Beck Hansen, J.; Belymam, A.; Bremer, J.; Chevalley, J. L.; Fassnacht, P.; Gianotti, F.; Hervas, L.; Marin, C. P.; Pailler, P.; Schilly, P.; Seidl, W.; Vossebeld, J.; Vuillemin, V.; Clark, A.; Efthymiopoulos, I.; Moneta, L.; Belhorma, B.; Collot, J.; de Saintignon, P.; Dzahini, D.; Ferrari, A.; Gallin-Martel, M. L.; Hostachy, J. Y.; Martin, P.; Muraz, J. F.; Ohlsson-Malek, F.; Saboumazrag, S.; Ban, J.; Cartiglia, N.; Cunitz, H.; Dodd, J.; Gara, A.; Leltchouk, M.; Negroni, S.; Parsons, J. A.; Seman, M.; Simion, S.; Sippach, W.; Willis, W.; Barreiro, F.; Garcia, G.; Labarga, L.; Rodier, S.; Del Peso, J.; Alexa, C.; Barrillon, P.; Benchouk, C.; Chekhtman, A.; Dinkespiler, B.; Djama, F.; Duval, P. Y.; Henry-Couannier, F.; Hinz, L.; Jevaud, M.; Karst, P.; Le van Suu, A.; Martin, L.; Martin, O.; Mirea, A.; Monnier, E.; Nagy, E.; Nicod, D.; Olivier, C.; Pralavorio, P.; Repetti, B.; Raymond, M.; Sauvage, D.; Tisserant, S.; Toth, J.; Wielers, M.; Battistoni, G.; Bonivento, W.; Carminati, L.; Cavalli, D.; Costa, G.; Delmastro, M.; Fanti, M.; Mandelli, L.; Mazzanti, M.; Perini, L.; Resconi, S.; Tartarelli, G. F.; Aulchenko, V.; Kazanin, V.; Kolachev, G.; Malyshev, V.; Maslennikov, A.; Pospelov, G.; Snopkov, R.; Shousharo, A.; Talyshev, A.; Tikhonov, Yu.; Augé, E.; Bourdarios, C.; Breton, D.; Cros, P.; de La Taille, C.; Falleau, I.; Fournier, D.; Guilhem, G.; Hassani, S.; Jacquier, Y.; Kordas, K.; Macé, G.; Merkel, B.; Noppe, J. M.; Parrour, G.; Pétroff, P.; Puzo, P.; Richer, J. P.; Rousseau, D.; Seguin-Moreau, N.; Serin, L.; Tocut, V.; Veillet, J. J.; Zerwas, D.; Astesan, F.; Bertoli, W.; Camard, A.; Canton, B.; Fichet, S.; Hubaut, F.; Imbault, D.; Lacour, D.; Laforge, B.; Le Dortz, O.; Martin, D.; Nikolic-Audit, I.; Orsini, F.; Rossel, F.; Schwemling, P.; Cleland, W.; McDonald, J.; Abouelouafa, E. M.; Ben Mansour, A.; Cherkaoui, R.; El Mouahhidi, Y.; Ghazlane, H.; Idrissi, A.; Belorgey, J.; Bernard, R.; Chalifour, M.; Le Coroller, A.; Ernwein, J.; Mansoulié, B.; Renardy, J. F.; Schwindling, J.; Taguet, J.-P.; Teiger, J.; Clément, C.; Lund-Jensen, B.; Lundqvist, J.; Megner, L.; Pearce, M.; Rydstrom, S.; Egdemir, J.; Engelmann, R.; Hoffman, J.; McCarthy, R.; Rijssenbeek, M.; Steffens, J.; Atlas Electromagnetic Liquid Argon Calorimeter Group

    2003-03-01

    The construction and performance of the barrel pre-series module 0 of the future ATLAS electromagnetic calorimeter at the LHC is described. The signal reconstruction and performance of ATLAS-like electronics has been studied. The signal to noise ratio for muons has been found to be 7.11±0.07. An energy resolution of better than 9.5% GeV1/2/ E (sampling term) has been obtained with electron beams of up to 245 GeV. The uniformity of the response to electrons in an area of Δ η×Δ φ=1.2×0.075 has been measured to be better than 0.8%.

  9. Calibration of BGO Calorimeter of the DAMPE in Space

    NASA Astrophysics Data System (ADS)

    Wang, Chi

    2016-07-01

    The Dark Matter Particle Explore (DAMPE) is a satellite based experiment which launched on December 2015 and aims at indirect searching for dark matter by measuring the spectra of high energy e±, γ from 5GeV up to 10TeV originating from deep space. The 3D imaging BGO calorimeter of DAMPE was designed to precisely measurement the primary energy of the electromagnetic particle and provides a highly efficient rejection of the hadronic background by reconstruct the longitudinal and lateral profiles of showers. To achieve the expected accuracy on the energy measurement, each signal channel has to be calibrated. The energy equalization is performed using the signal that Minimum Ionizing Particles (MIP) leave in each BGO bar, the MIPs measurement method with orbit data and, data quality, time stability using MIPs data will be presented, too.

  10. A new-concept gamma calorimeter at ELI-NP

    NASA Astrophysics Data System (ADS)

    Lenzi, M.; Adriani, O.; Albergo, S.; Andreotti, M.; Berto, D.; Borgheresi, R.; Cappello, G.; Cardarelli, P.; Ciaranfi, R.; Consoli, E.; Di Domenico, G.; Evangelisti, F.; Gambaccini, M.; Graziani, G.; Marziani, M.; Palumbo, L.; Passaleva, G.; Pellegriti, M. G.; Serban, A.; Starodubtsev, O.; Statera, M.; Tricomi, A.; Variola, A.; Veltri, M.

    2017-02-01

    ELI-NP is an European Research Infrastructure that will provide a monochromatic, high brilliance gamma beam with tunable energy up to 19.5 MeV. The time structure of the beam consists of 32 high intensity gamma bunches separated by a time interval of 16 ns and delivered at a repetition rate of 100 Hz. In order to match such unprecedented beam specifications, specific devices and techniques have been developed to measure and monitor the beam parameters during the commissioning and the operational phase. This paper presents an overview of the gamma beam characterization system, with particular focus on a new-concept sampling calorimeter made of silicon detectors and polyethylene absorbers.

  11. Progress report for the scintillator plate calorimeter subsystem

    SciTech Connect

    Not Available

    1990-12-31

    This report covers the work completed in FY90 by ANL staff and those of Westinghouse STC and BICRON Corporation under subcontract to ANL towards the design of a compensating calorimeter based on the use of scintillator plate as the sensitive medium. It is presented as five task sections dealing with respectively mechanical design; simulation studies; optical system design; electronics development; development of rad hard plastic scintillator and wavelength shifter and a summary. The work carried out by the University of Tennessee under a subcontract from ANL is reported separately. Finally, as principal institution with responsibility for the overall management of this subsystem effort, the summary here reports the conclusions resulting from the work of the collaboration and their impact on our proposed direction of effort in FY91. This proposal, for obvious reasons is given separately.

  12. Can a PB / SCIFI Calorimeter Survive the SSC?

    SciTech Connect

    D. W. Hertzog; S. A. Hughes; P. E. Reimer; R. L. Tayloe; K. F. Johnson; S. Majewski; C. Zorn; M. Zorn

    1990-03-01

    A scintillating fiber based electromagnetic calorimeter module built from radiation-hard materials has been tested in a beam capable of delivering both low and high currents of monoenergetic electrons. Energy resolution and light output measurements were made following high-dose exposures. The procedure was repeated until the resolution of the detector decreased from an initial value of 6.9%/sqrt E to 14.0%/sqrt E and the pulse height dropped by a factor of 11. After four weeks, the detector was retested. Partial recovery was observed in the light output which returned to approximately 52% of its original value. The resolution recovered to a value of 8.8%/sqrt E. The tests are described.

  13. Can a Pb/SCIFI calorimeter survive the SSC

    SciTech Connect

    Hertzog, D.W.; Hughes, S.A.; Reimer, P.E.; Tayloe, R.L. ); Johnson, K.F. ); Majewski, S.; Zorn, C.; Zorn, M. )

    1990-01-01

    A scintillating fiber based electromagnetic calorimeter module built from radiation-hard materials has been tested in a beam capable of delivering both low and high currents of monoenergetic electrons. Energy resolution and light output measurements were made following high-dose exposures. The procedure was repeated until the resolution of the detector decreased from an initial value of 6.9%{radical}E to 14.0%{radical}E and the pulse height dropped by a factor of 11. After four weeks, the detector was retested. Partial recovery was observed in the light output which returned to approximately 52% of its original value. The resolution recovered to a value of 8.8%{radical}E. The tests are described. 9 refs., 4 figs.

  14. The CMS Hadron Forward Calorimeter Upgrade During Phase I

    NASA Astrophysics Data System (ADS)

    Gülmez, E.

    2014-06-01

    The CMS Hadron Forward Calorimeter is being upgraded during phase 1. The upgrade includes the replacement of the current PMTs with the 4-anode ones and the readout electronics. Stray muons hitting the PMT windows produce Cherenkov light causing erroneous signals. These signals are detrimental to the triggering and physic results, since such signals mimic very high energy events. The new 4-anode PMTs are selected because of their thin windows to reduce the Cherenkov light production. Additional anodes also provide information to eliminate such signals. These new PMTs have been tested extensively to understand their characteristics and to develop the algorithms to eliminate the unwanted signals. Eventually, the current read out will be replaced with two-channel readout electronics for each PMT. The overall expected improvement on the physics results will also be discussed.

  15. The magnetized steel and scintillator calorimeters of the MINOS experiment

    SciTech Connect

    Michael, : D.G.

    2008-05-01

    The Main Injector Neutrino Oscillation Search (MINOS) experiment uses an accelerator-produced neutrino beam to perform precision measurements of the neutrino oscillation parameters in the 'atmospheric neutrino' sector associated with muon neutrino disappearance. This long-baseline experiment measures neutrino interactions in Fermilab's NuMI neutrino beam with a near detector at Fermilab and again 735 km downstream with a far detector in the Soudan Underground Laboratory in northern Minnesota. The two detectors are magnetized steel-scintillator tracking calorimeters. They are designed to be as similar as possible in order to ensure that differences in detector response have minimal impact on the comparisons of event rates, energy spectra and topologies that are essential to MINOS measurements of oscillation parameters. The design, construction, calibration and performance of the far and near detectors are described in this paper.

  16. ATLAS level-1 calorimeter trigger: Monitoring and data reprocessing

    NASA Astrophysics Data System (ADS)

    Dimond, David; Hong, Tae; Carlson, Benjamin; Atlas Collaboration

    2017-01-01

    We present the monitoring and data reprocessing for the calorimeter-based hardware level-1 trigger system (L1Calo) for the ATLAS experiment. This trigger system was upgraded after the Run-1 data taking period (2009-2012) to prepare for Run-2 (2015-current), which allowed better control the event rates for algorithms based on jets and/or missing energy. Monitoring tools for the upgraded system is described. We also present a new offline tool to reprocess previous data samples with altered L1Calo settings, such as calibration constants and noise cuts. The samples are used to study the dependence of the event rates and signal efficiencies on the settings. The studies can help plan the appropriate L1Calo settings for upcoming data taking periods as well as for future runs.

  17. The upgrade of the Belle II forward calorimeter

    NASA Astrophysics Data System (ADS)

    Manoni, E.; Aloisio, A.; Baccaro, S.; Branchini, P.; Cecchi, C.; Cemmi, A.; De Lucia, E.; De Nardo, G.; de Sangro, R.; Felici, G.; Finocchiaro, G.; Fiore, S.; Giordano, R.; Merola, M.; Oberhof, B.; Passeri, A.; Peruzzi, I. M.; Piccolo, M.; Rossi, A.; Sciacca, C.

    2017-02-01

    The new facility SuperKEKB will be an upgrade of the existing KEKB electron-positron asymmetric collider, with a target luminosity of 8 ×1035cm-2s-1, about 40 times greater than that of KEKB. The detector will also be upgraded to cope with the higher luminosity, pile-up and occupancy. We report here on the design and development of the new pure CsI calorimeter for the forward region. An intensive R&D is being carried on to study the performance of pure CsI crystals with Avalanche Photodiodes readout. Results about the relative energy resolution of this detector, along with radiation hardness studies of all the components, are presented. A matrix of 16 crystals has been put on an electron beam at the BTF facility in Frascati and results in terms of energy resolution of this prototype are also discussed.

  18. A high precision calorimeter for the SOX experiment

    NASA Astrophysics Data System (ADS)

    Papp, L.; Agostini, M.; Altenmüller, K.; Appel, S.; Caminata, A.; Cereseto, R.; Di Noto, L.; Farinon, S.; Musenich, R.; Neumair, B.; Oberauer, L.; Pallavicini, M.; Schönert, S.; Testera, G.; Zavatarelli, S.

    2016-07-01

    The SOX (Short distance neutrino Oscillations with BoreXino) experiment is being built to discover or reject eV-scale sterile neutrinos by observing short baseline oscillations of active-to-sterile neutrinos [1]. For this purpose, a 100 kCi 144Ce-144Pr antineutrino generator (CeSOX) will be placed under the BOREXINO detector at the Laboratori Nazionali del Gran Sasso. Thanks to its large size and very low background, BOREXINO is an ideal detector to discover or reject eV-scale sterile neutrinos. To reach the maximal sensitivity, we aim at determining the neutrino flux emitted by the antineutrino generator with a < 1 % accuracy. With this goal, TU München and INFN Genova are developing a vacuum calorimeter, which is designed to measure the source-generated heat with high accuracy.

  19. Geant4 validation with CMS calorimeters test-beam data

    SciTech Connect

    Piperov, Stefan; /Sofiya, Inst. Nucl. Res. /Fermilab

    2008-08-01

    CMS experiment is using Geant4 for Monte-Carlo simulation of the detector setup. Validation of physics processes describing hadronic showers is a major concern in view of getting a proper description of jets and missing energy for signal and background events. This is done by carrying out an extensive studies with test beam using the prototypes or real detector modules of the CMS calorimeter. These data are matched with Geant4 predictions. Tuning of the Geant4 models is carried out and steps to be used in reproducing detector signals are defined in view of measurements of energy response, energy resolution, transverse and longitudinal shower profiles for a variety of hadron beams over a broad energy spectrum between 2 to 300 GeV/c.

  20. Radiation hard programmable delay line for LHCb calorimeter upgrade

    NASA Astrophysics Data System (ADS)

    Mauricio, J.; Gascón, D.; Vilasís, X.; Picatoste, E.; Machefert, F.; Lefrancois, J.; Duarte, O.; Beigbeder, C.

    2014-01-01

    This paper describes the implementation of a SPI-programmable clock delay chip based on a Delay Locked Loop (DLL) in order to shift the phase of the LHC clock (25 ns) in steps of 1ns, with less than 5 ps jitter and 23 ps of DNL. The delay lines will be integrated into ICECAL, the LHCb calorimeter front-end analog signal processing ASIC in the near future. The stringent noise requirements on the ASIC imply minimizing the noise contribution of digital components. This is accomplished by implementing the DLL in differential mode. To achieve the required radiation tolerance several techniques are applied: double guard rings between PMOS and NMOS transistors as well as glitch suppressors and TMR Registers. This 5.7 mm2 chip has been implemented in CMOS 0.35 μm technology.

  1. Monitoring the stability of the CMS electromagnetic calorimeter

    NASA Astrophysics Data System (ADS)

    Ferri, Federico

    2011-04-01

    The lead tungstate electromagnetic calorimeter of the CMS experiment has been proved to achieve an excellent energy resolution during the commissioning phase of the detector. The uniformity of the relative response of individual channels and the energy scale for electrons and photons are constrained by the several calibration procedures. The stability of the detector in time is constantly monitored throughout the LHC operation by means of dedicated runs and data taken at 100 Hz in the 3 μs abort gap at the end of each 89 μs beam cycle. A laser monitoring system is used to track the single channel response variations with time, as changes of the crystal transparency caused by irradiation. The stability of crucial detector parameters such as high voltage, temperature and electronic noise and the performance of the operation of the light monitoring system are shown to fulfill the requirements needed to achieve the target resolution of 0.5% at high energies.

  2. The Electron Calorimeter (ECAL) Long Duration Balloon Experiment

    NASA Technical Reports Server (NTRS)

    Guzik, T. G.; Adams, J. H.; Bashindzhagyan, G.; Binns, W. R.; Chang, J.; Cherry, M. L.; Christl, M.; Dowkontt, P.; Ellison, B.; Isbert, J. B.; Israel, M. H.; Korotkova, N.; Panasyuk, M.; Panov, A.; Sokolskaya, N.; Stewart, M.; Watts, J.; Wefel, P.; Zatsepin, V.

    2007-01-01

    Accurate measurements of the cosmic ray electron energy spectrum in the energy region 50 GeV to greater than 1 TeV may reveal structure caused by the annihilation of exotic dark matter particles and/or individual cosmic ray sources. Here we describe a new long duration balloon (LDB) experiment, ECAL, optimized to directly measure cosmic ray electrons up to several TeV. ECAL includes a double layer silicon matrix, a scintillating optical fiber track imager, a neutron detector and a fully active calorimeter to identify more than 90% of the incident electrons with an energy resolution of about 1.7% while misidentifying only 1 in 200,000 protons and 0.8% of secondary gamma rays as electrons. Two ECAL flights in Antarctica are planned for a total exposure of 50 days with the first flight anticipate for December 2009.

  3. Finite element analysis of the SDC barrel and endcap calorimeters

    SciTech Connect

    Guarino, V.; Hill, N.; Nasiakta, J.

    1992-03-11

    In designing the SCD barrel and endcap calorimeters, the inter-module connecting forces must be known in order to determine the required size and number of connecting links between modules, and in order to understand how individual modules will be affected by these forces when assembled to form a full barrel and endcap. The connecting forces were found by analyzing three-dimensional Finite Element Models of both the barrel and endcap. This paper is divided into two parts, the first part will describe in detail the results of the barrel analysis and the second part will describe the results obtained from the endcap analysis. A similar approach was used in constructing the models for both analysis.

  4. Liquid chromatography-electrospray linear ion trap mass spectrometry analysis of targeted neuropeptides in Tac1(-/-) mouse spinal cords reveals significant lower concentration of opioid peptides.

    PubMed

    Saidi, Mouna; Beaudry, Francis

    2015-08-01

    Tachykinin and opioid peptides play a central role in pain transmission, modulation and inhibition. The treatment of pain is very important in medicine and many studies using NK1 receptor antagonists failed to show significant analgesic effects in humans. Recent investigations suggest that both pronociceptive tachykinins and the analgesic opioid systems are important for normal pain sensation. The analysis of opioid peptides in Tac1(-/-) spinal cord tissues offers a great opportunity to verify the influence of the tachykinin system on specific opioid peptides. The objectives of this study were to develop an HPLC-MS/MRM assay to quantify targeted peptides in spinal cord tissues. Secondly, we wanted to verify if the Tac1(-/-) mouse endogenous opioid system is hampered and therefore affects significantly the pain modulatory pathways. Targeted neuropeptides were analyzed by high performance liquid chromatography linear ion trap mass spectrometry. Our results reveal that EM-2, Leu-Enk and Dyn A were down-regulated in Tac1(-/-) spinal cord tissues. Interestingly, Dyn A was almost 3 fold down-regulated (p<0.0001). No significant concentration differences were observed in mouse Tac1(-/-) spinal cords for Met-Enk and CGRP. The analysis of Tac1(-/-) mouse spinal cords revealed noteworthy decreases of EM-2, Leu-Enk and Dyn A concentrations which strongly suggest a significant impact on the endogenous pain-relieving mechanisms. These observations may have insightful impact on future analgesic drug developments and therapeutic strategies.

  5. ABSORPTION ANALYZER

    DOEpatents

    Brooksbank, W.A. Jr.; Leddicotte, G.W.; Strain, J.E.; Hendon, H.H. Jr.

    1961-11-14

    A means was developed for continuously computing and indicating the isotopic assay of a process solution and for automatically controlling the process output of isotope separation equipment to provide a continuous output of the desired isotopic ratio. A counter tube is surrounded with a sample to be analyzed so that the tube is exactly in the center of the sample. A source of fast neutrons is provided and is spaced from the sample. The neutrons from the source are thermalized by causing them to pass through a neutron moderator, and the neutrons are allowed to diffuse radially through the sample to actuate the counter. A reference counter in a known sample of pure solvent is also actuated by the thermal neutrons from the neutron source. The number of neutrons which actuate the detectors is a function of a concentration of the elements in solution and their neutron absorption cross sections. The pulses produced by the detectors responsive to each neu tron passing therethrough are amplified and counted. The respective times required to accumulate a selected number of counts are measured by associated timing devices. The concentration of a particular element in solution may be determined by utilizing the following relation: T2/Ti = BCR, where B is a constant proportional to the absorption cross sections, T2 is the time of count collection for the unknown solution, Ti is the time of count collection for the pure solvent, R is the isotopic ratlo, and C is the molar concentration of the element to be determined. Knowing the slope constant B for any element and when the chemical concentration is known, the isotopic concentration may be readily determined, and conversely when the isotopic ratio is known, the chemical concentrations may be determined. (AEC)

  6. ATLAS LAr calorimeter performance and LHC Run-2 commissioning

    NASA Astrophysics Data System (ADS)

    Spettel, Fabian

    2016-07-01

    The ATLAS detector was built to study proton-proton collisions produced by the Large Hadron Collider (LHC) at a center of mass energy of up to 14 TeV. The Liquid Argon (LAr) calorimeters are used for all electromagnetic calorimetry as well as the hadronic calorimetry in the endcap and forward regions. They have shown excellent performance during the first LHC data taking campaign, from 2010 to 2012, so-called Run 1, at a peak luminosity of 8 ×1033cm-2s-1. During the next run, peak luminosities of 1.5 ×1034cm-2s-1 and even higher are expected at a 25 ns bunch spacing. Such a high collision rate may have an impact on the quality of the energy reconstruction which is attempted to be maintained at a high level using a calibration procedure described in this contribution. It also poses major challenges to the first level of the trigger system which is constrained to a maximal rate of 100 kHz. For Run-3, scheduled to start in 2019, instantaneous luminosity as high as 3 ×1034cm-2s-1 are foreseen imposing an upgrade of the LAr trigger system to maintain its performance. A demonstrator containing prototypes of the upgraded trigger electronic architecture has been installed on one of the barrel electromagnetic calorimeter readout front end crates to test it during the Run-2 campaign. The new architecture and its benefits for data taking will be discussed below as well as the results from first beam splash events.

  7. Design of Refractory Metal Life Test Heat Pipe and Calorimeter

    NASA Technical Reports Server (NTRS)

    Martin, J. J.; Reid, R. S.; Bragg-Sitton, S. M.

    2010-01-01

    Heat pipe life tests have seldom been conducted on a systematic basis. Typically, one or more heat pipes are built and tested for an extended period at a single temperature with simple condenser loading. Results are often reported describing the wall material, working fluid, test temperature, test duration, and occasionally the nature of any failure. Important information such as design details, processing procedures, material assay, power throughput, and radial power density are usually not mentioned. We propose to develop methods to generate carefully controlled data that conclusively establish heat pipe operating life with material-fluid combinations capable of extended operation. The test approach detailed in this Technical Publication will use 16 Mo-44.5%Re alloy/sodium heat pipe units that have an approximate12-in length and 5/8-in diameter. Two specific test series have been identified: (1) Long-term corrosion rates based on ASTM-G-68-80 (G-series) and (2) corrosion trends in a cross-correlation sequence at various temperatures and mass fluences based on a Fisher multifactor design (F-series). Evaluation of the heat pipe hardware will be performed in test chambers purged with an inert purified gas (helium or helium/argon mixture) at low pressure (10-100 torr) to provide thermal coupling between the heat pipe condenser and calorimeter. The final pressure will be selected to minimize the potential for voltage breakdown between the heat pipe and radio frequency (RF) induction coil (RF heating is currently the planned method of powering the heat pipes). The proposed calorimeter is constructed from a copper alloy and relies on a laminar flow water-coolant channel design to absorb and transport energy

  8. Low expression of NQO1 predicts pathological complete response to neoadjuvant chemotherapy in breast cancer patients treated with TAC regimen.

    PubMed

    Grim, J; Jandík, P; Slánská, I; Doležalová-Brčáková, E; Fuksa, L; Ryška, A; Knížek, J; Petera, J; Mičuda, S; Hornychová, H

    2012-01-01

    The aim of this study was to evaluate preoperative tumour expression of NAD(P)H:quinone oxidoreductase 1 (NQO1) along with other biological markers as potential predictors of pathological complete response (pCR) to neoadjuvant docetaxel, doxorubicin, and cyclophosphamide-containing (TAC) chemotherapy in patients with primary breast cancer. Sixty-one patients who received neoadjuvant chemotherapy (NCT) with TAC regimen were enrolled in this prospective study. The pre- and post- NCT expression of oestrogen receptor (ER), progesterone receptor (PR), epidermal growth factor receptor 1 and 2 (EGFR and HER2), NQO1, Ki-67 proliferation index, multidrug resistance protein 1 (MDR1), p53 and BCL2 were evaluated by immunohistochemistry. The pCR was reached in 14 patients (23 % of the study group). Multivariate analysis demonstrated that patients with ER-, PR-, NQO1- negative, and Ki-67-positive tumours had a significantly higher chance to achieve pCR. Within the biological subtypes, the highest pCR rate (50 %) was seen in triple-negative (i.e. ER-, PR-, HER2-) tumours. Post-operative evaluation showed that in comparison to pre-operative tissue samples, NQO1 expression was significantly increased, while Ki-67 and HER2 decreased, in the residual tissue after NCT. In conclusion, the present data suggests that NQO1 expression may be a novel diagnostic biomarker for the prediction of positive response to NCT in patients with breast cancer.

  9. Lack of benefit of early protocol biopsies in renal transplant patients receiving TAC and MMF: a randomized study.

    PubMed

    Rush, D; Arlen, D; Boucher, A; Busque, S; Cockfield, S M; Girardin, C; Knoll, G; Lachance, J-G; Landsberg, D; Shapiro, J; Shoker, A; Yilmaz, S

    2007-11-01

    We conducted a randomized, multicenter study to determine whether treatment of subclinical rejection with increased corticosteroids resulted in beneficial outcomes in renal transplant patients receiving tacrolimus (TAC), mycophenolate mofetil (MMF) and prednisone. One hundred and twenty-one patients were randomized to biopsies at 0,1,2,3 and 6 months (Biopsy arm), and 119 to biopsies at 0 and 6 months only (Control arm). The primary endpoint of the study was the prevalence of the sum of the interstitial and tubular scores (ci + ct)> 2 (Banff) at 6 months. Secondary endpoints included clinical and subclinical rejection and renal function. At 6 months, 34.8% of the Biopsy and 20.5% of the Control arm patients had a ci + ct score >or= 2 (p = 0.07). Between months 0 and 6, clinical rejection episodes were 12 in 10 Biopsy arm patients and 8 in 8 Control arm patients (p = 0.44). Overall prevalence of subclinical rejection in the Biopsy arm was 4.6%. Creatinine clearance at 6 months was 72.9 +/- 21.7 in the Biopsy and 68.90 mL/min +/- 18.35 mL/min in the Control arm patients (p = 0.18). In conclusion, we found no benefit to the procurement of early protocol biopsies in renal transplant patients receiving TAC, MMF and prednisone, at least in the short term. This is likely due to their low prevalence of subclinical rejection.

  10. Rapid measurement of total acid content (TAC) in vinegar using near infrared spectroscopy based on efficient variables selection algorithm and nonlinear regression tools.

    PubMed

    Chen, Quansheng; Ding, Jiao; Cai, Jianrong; Zhao, Jiewen

    2012-11-15

    Total acid content (TAC) is an important index in assessing vinegar quality. This work attempted to determine TAC in vinegar using near infrared spectroscopy. We systematically studied variable selection and nonlinear regression in calibrating regression models. First, the efficient spectra intervals were selected by synergy interval PLS (Si-PLS); then, two nonlinear regression tools, which were extreme learning machine (ELM) and back propagation artificial neural network (BP-ANN), were attempted. Experiments showed that the model based on ELM and Si-PLS (Si-ELM) was superior to others, and the optimum results were achieved as follows: the root mean square error of prediction (RMSEP) was 0.2486 g/100mL, and the correlation coefficient (R(p)) was 0.9712 in the prediction set. This work demonstrated that the TAC in vinegar could be rapidly measured by NIR spectroscopy and Si-ELM algorithm showed its superiority in model calibration.

  11. The Laser calibration of the ATLAS Tile Calorimeter during the LHC run 1

    NASA Astrophysics Data System (ADS)

    Abdallah, J.; Alexa, C.; Amaral Coutinho, Y.; Amor Dos Santos, S. P.; Anderson, K. J.; Arabidze, G.; Araque, J. P.; Artamonov, A.; Asquith, L.; Astalos, R.; Backus Mayes, J.; Bartos, P.; Batkova, L.; Bertolucci, F.; Bessidskaia Bylund, O.; Blanco Castro, A.; Blazek, T.; Bohm, C.; Boumediene, D.; Boveia, A.; Brown, H.; Busato, E.; Calkins, R.; Calvet, D.; Calvet, S.; Camacho Toro, R.; Caminal Armadans, R.; Carli, T.; Carvalho, J.; Cascella, M.; Castro, N. F.; Cavasinni, V.; Cerqueira, A. S.; Chadelas, R.; Chakraborty, D.; Chekanov, S.; Chen, X.; Chikovani, L.; Choudalakis, G.; Cinca, D.; Ciubancan, M.; Clement, C.; Cole, S.; Constantinescu, S.; Costin, T.; Crouau, M.; Crozatier, C.; Cuciuc, C.-M.; Da Cunha Sargedas De Sousa, M. J.; Darmora, S.; Davidek, T.; Del Prete, T.; Dita, S.; Djobava, T.; Dolejsi, J.; Dotti, A.; Dubreuil, E.; Dunford, M.; Eriksson, D.; Errede, S.; Errede, D.; Faltova, J.; Farbin, A.; Febbraro, R.; Federic, P.; Feng, E. J.; Ferrer, A.; Fiascaris, M.; Fiolhais, M. C. N.; Fiorini, L.; Francavilla, P.; Fullana Torregrosa, E.; Galhardo, B.; Gellerstedt, K.; Ghodbane, N.; Giakoumopoulou, V.; Giangiobbe, V.; Giokaris, N.; Glonti, G. L.; Gomes, A.; Gonzalez Parra, G.; Grenier, P.; Grinstein, S.; Gris, Ph.; Guicheney, C.; Hakobyan, H.; Hard, A. S.; Harkusha, S.; Heelan, L.; Helsens, C.; Henriques Correia, A. M.; Hernández Jiménez, Y.; Hernandez, C. M.; Higón-Rodriguez, E.; Hurwitz, M.; Huseynov, N.; Huston, J.; Jen-La Plante, I.; Jennens, D.; Johansson, K. E.; Jon-And, K.; Jorge, P. M.; Juste Rozas, A.; Kapliy, A.; Karpov, S. N.; Karyukhin, A. N.; Khandanyan, H.; Khramov, E.; Khubua, J.; Kim, H.; Klimek, P.; Korolkov, I.; Kruse, A.; Kulchitsky, Y.; Kurochkin, Y. A.; Lafarguette, P.; Lambert, D.; LeCompte, T.; Leitner, R.; Leone, S.; Liao, H.; Lie, K.; Lokajicek, M.; Lundberg, O.; Magalhaes Martins, P. J.; Maio, A.; Makouski, M.; Maneira, J.; Filho, L. Manhaes de Andrade; Manousakis-Katsikakis, A.; Martin, B.; Mchedlidze, G.; Meehan, S.; Mellado Garcia, B. R.; Meoni, E.; Merritt, F. S.; Meyer, C.; Miller, D. W.; Milstead, D. A.; Minashvili, I. A.; Mir, L. M.; Molander, S.; Montejo Berlingen, J.; Mosidze, M.; Myagkov, A. G.; Nemecek, S.; Nepomuceno, A. A.; Nguyen, D. H.; Nikolaenko, V.; Nilsson, P.; Nodulman, L.; Nordkvist, B.; Ohm, C. C.; Olariu, A.; Oleiro Seabra, L. F.; Onofre, A.; Oreglia, M. J.; Pallin, D.; Pantea, D.; Paredes Hernandez, D.; Pedraza Morales, M. I.; Pedro, R.; Martins, F. M. Pedro; Peng, H.; Penning, B.; Pilcher, J. E.; Pina, J.; Pleskot, V.; Plotnikova, E.; Podlyski, F.; Popeneciu, G. A.; Poveda, J.; Pravahan, R.; Pribyl, L.; Price, L. E.; Proudfoot, J.; Rocha de Lima, J. G.; Roda, C.; Roda Dos Santos, D.; Romano Saez, S. M.; Rossetti, V.; Ruiz-Martinez, A.; Rusakovich, N. A.; Salvachua Ferrando, B. M.; Santoni, C.; Santos, H.; Saraiva, J. G.; Says, L. P.; Schwartzman, A.; Scuri, F.; Shimizu, S.; Silva, J.; Silverstein, S. B.; Solans, C. A.; Solodkov, A. A.; Solovyanov, O. V.; Spalla, M.; Stanek, R. W.; Starchenko, E. A.; Starovoitov, P.; Stavina, P.; Stoicea, G.; Succurro, A.; Suhr, C.; Sumida, T.; Sykora, I.; Tas, P.; Tavares Delgado, A.; Tokár, S.; Tsiareshka, P. V.; Tsiskaridze, V.; Tudorache, V.; Tudorache, A.; Tuggle, J. M.; Tylmad, M.; Usai, G.; Valero, A.; Valery, L.; Valladolid Gallego, E.; Valls Ferrer, J. A.; Vazeille, F.; Veloso, F.; Vichou, I.; Vinogradov, V. B.; Viret, S.; Volpi, M.; Wang, C.; Weng, Z.; White, A.; Wilkens, H. G.; Yanush, S.; Yoshida, R.; Zhang, L.; Zhu, Y.; Zinonos, Z.; Zutshi, V.; Ženiš, T.; van Woerden, M. C.

    2016-10-01

    This article describes the Laser calibration system of the ATLAS hadronic Tile Calorimeter that has been used during the run 1 of the LHC . First, the stability of the system associated readout electronics is studied. It is found to be stable with variations smaller than 0.6 %. Then, the method developed to compute the calibration constants, to correct for the variations of the gain of the calorimeter photomultipliers, is described. These constants were determined with a statistical uncertainty of 0.3 % and a systematic uncertainty of 0.2 % for the central part of the calorimeter and 0.5 % for the end-caps. Finally, the detection and correction of timing mis-configuration of the Tile Calorimeter using the Laser system are also presented.

  12. Simulation of π0-γ Separation Study for Proposed CMS Forward Electromagnetic Calorimeter

    NASA Astrophysics Data System (ADS)

    Roy, Ashim; Jain, Shilpi; Banerjee, Sunanda; Bhattacharya, Satyaki; Majumder, Gobinda

    2016-10-01

    The Forward Electromagnetic Calorimeter of the CMS detector is going to be upgraded in the high luminosity running as the energy of the present Electromagnetic Calorimeter (PbWO4) will degrade in the high luminosity (luminosity 1034 cm -2 s -1) running due to extensive radiation (hadron flux 1013neutrons cm,-2). Shashlik Electromagnetic Calorimeter which consists of alternate layers of 1.5 mm LYSO(Ce) crystal plates and 2.5 mm Tungsten absorbers, was a proposal for high luminosity running. One of the performance points for any electromagnetic calorimeter is the ability to separate π0 s from true photons, since final states with photons are a clean and one of the most important final states in proton-proton collisions at the LHC. The objective of this project is to study the possibility of π0 and γ separation in the Shashlik detector using Multivariate Analysis (MVA) technique.

  13. Monte Carlo study of the influence of magnetic field on energy measurements in calorimeters

    NASA Astrophysics Data System (ADS)

    Abramov, V. V.

    1996-02-01

    The influence of magnetic field on energy measurements in calorimeters is studied by Monte Carlo methods. It is shown that magnetic field influence depends on type of incident particles and on material and thickness of absorber plates.

  14. The Laser calibration of the ATLAS Tile Calorimeter during the LHC run 1

    SciTech Connect

    Abdallah, J.; Alexa, C.; Coutinho, Y. Amaral; Santos, S. P. Amor Dos; Anderson, K. J.; Arabidze, G.; Araque, J. P.; Artamonov, A.; Asquith, L.; Astalos, R.; Mayes, J. Backus; Bartos, P.; Batkova, L.; Bertolucci, F.; Bylund, O. Bessidskaia; Castro, A. Blanco; Blazek, T.; Bohm, C.; Boumediene, D.; Boveia, A.; Brown, H.; Busato, E.; Calkins, R.; Calvet, D.; Calvet, S.; Toro, R. Camacho; Armadans, R. Caminal; Carli, T.; Carvalho, J.; Cascella, M.; Castro, N. F.; Cavasinni, V.; Cerqueira, A. S.; Chadelas, R.; Chakraborty, D.; Chekanov, S.; Chen, X.; Chikovani, L.; Choudalakis, G.; Cinca, D.; Ciubancan, M.; Clement, C.; Cole, S.; Constantinescu, S.; Costin, T.; Crouau, M.; Crozatier, C.; Cuciuc, C. -M.; De Sousa, M. J. Da Cunha Sargedas; Darmora, S.; Davidek, T.; Prete, T. Del; Dita, S.; Djobava, T.; Dolejsi, J.; Dotti, A.; Dubreuil, E.; Dunford, M.; Eriksson, D.; Errede, S.; Errede, D.; Faltova, J.; Farbin, A.; Febbraro, R.; Federic, P.; Feng, E. J.; Ferrer, A.; Fiascaris, M.; Fiolhais, M. C. N.; Fiorini, L.; Francavilla, P.; Torregrosa, E. Fullana; Galhardo, B.; Gellerstedt, K.; Ghodbane, N.; Giakoumopoulou, V.; Giangiobbe, V.; Giokaris, N.; Glonti, G. L.; Gomes, A.; Parra, G. Gonzalez; Grenier, P.; Grinstein, S.; Gris, Ph.; Guicheney, C.; Hakobyan, H.; Hard, A. S.; Harkusha, S.; Heelan, L.; Helsens, C.; Correia, A. M. Henriques; Jiménez, Y. Hernández; Hernandez, C. M.; Higón-Rodriguez, E.; Hurwitz, M.; Huseynov, N.; Huston, J.; Plante, I. Jen-La; Jennens, D.; Johansson, K. E.; Jon-And, K.; Jorge, P. M.; Rozas, A. Juste; Kapliy, A.; Karpov, S. N.; Karyukhin, A. N.; Khandanyan, H.; Khramov, E.; Khubua, J.; Kim, H.; Klimek, P.; Korolkov, I.; Kruse, A.; Kulchitsky, Y.; Kurochkin, Y. A.; Lafarguette, P.; Lambert, D.; LeCompte, T.; Leitner, R.; Leone, S.; Liao, H.; Lie, K.; Lokajicek, M.; Lundberg, O.; Martins, P. J. Magalhaes; Maio, A.; Makouski, M.; Maneira, J.; Filho, L. Manhaes de Andrade; Manousakis-Katsikakis, A.; Martin, B.; Mchedlidze, G.; Meehan, S.; Garcia, B. R. Mellado; Meoni, E.; Merritt, F. S.; Meyer, C.; Miller, D. W.; Milstead, D. A.; Minashvili, I. A.; Mir, L. M.; Molander, S.; Berlingen, J. Montejo; Mosidze, M.; Myagkov, A. G.; Nemecek, S.; Nepomuceno, A. A.; Nguyen, D. H.; Nikolaenko, V.; Nilsson, P.; Nodulman, L.; Nordkvist, B.; Ohm, C. C.; Olariu, A.; Seabra, L. F. Oleiro; Onofre, A.; Oreglia, M. J.; Pallin, D.; Pantea, D.; Hernandez, D. Paredes; Morales, M. I. Pedraza; Pedro, R.; Martins, F. M. Pedro; Peng, H.; Penning, B.; Pilcher, J. E.; Pina, J.; Pleskot, V.; Plotnikova, E.; Podlyski, F.; Popeneciu, G. A.; Poveda, J.; Pravahan, R.; Pribyl, L.; Price, L. E.; Proudfoot, J.; de Lima, J. G. Rocha; Roda, C.; Santos, D. Roda Dos; Saez, S. M. Romano; Rossetti, V.; Ruiz-Martinez, A.; Rusakovich, N. A.; Ferrando, B. M. Salvachua; Santoni, C.; Santos, H.; Saraiva, J. G.; Says, L. P.; Schwartzman, A.; Scuri, F.; Shimizu, S.; Silva, J.; Silverstein, S. B.; Solans, C. A.; Solodkov, A. A.; Solovyanov, O. V.; Spalla, M.; Stanek, R. W.; Starchenko, E. A.; Starovoitov, P.; Stavina, P.; Stoicea, G.; Succurro, A.; Suhr, C.; Sumida, T.; Sykora, I.; Tas, P.; Delgado, A. Tavares; Tokár, S.; Tsiareshka, P. V.; Tsiskaridze, V.; Tudorache, V.; Tudorache, A.; Tuggle, J. M.; Tylmad, M.; Usai, G.; Valero, A.; Valery, L.; Gallego, E. Valladolid; Ferrer, J. A. Valls; Vazeille, F.; Veloso, F.; Vichou, I.; Vinogradov, V. B.; Viret, S.; Volpi, M.; Wang, C.; Weng, Z.; White, A.; Wilkens, H. G.; Yanush, S.; Yoshida, R.; Zhang, L.; Zhu, Y.; Zinonos, Z.; Zutshi, V.; Ženiš, T.; van Woerden, M. C.

    2016-10-12

    This article describes the Laser calibration system of the ATLAS hadronic Tile Calorimeter that has been used during the run 1 of the LHC . First, the stability of the system associated readout electronics is studied. It is found to be stable with variations smaller than 0.6 %. Then, the method developed to compute the calibration constants, to correct for the variations of the gain of the calorimeter photomultipliers, is described. These constants were determined with a statistical uncertainty of 0.3 % and a systematic uncertainty of 0.2 % for the central part of the calorimeter and 0.5 % for the end-caps. Lastly, the detection and correction of timing mis-configuration of the Tile Calorimeter using the Laser system are also presented.

  15. A calorimeter for multilayer insulation (MLI) performance measurements at variable temperature

    NASA Astrophysics Data System (ADS)

    Celik, D.; Hurd, J.; Klimas, R.; Van Sciver, S. W.

    2013-05-01

    Here we describe a concentric cylindrical calorimeter with radiation guards developed to measure the thermal performance of multilayer insulation (MLI) for low temperature applications. One unique feature of this calorimeter is its ability to independently control the boundary temperatures between room temperature and about 15 K using two single-stage Gifford-McMahon cryocoolers. Also, unlike the existing calorimeters that use the evaporation rate of a liquid cryogen to measure the heat load, in the present system the total heat transfer through the MLI is measured by recording the temperature difference across a calibrated heat load support rod that connects the cold inner cylinder to the lower temperature cryocooler. This design allows the continuous mapping of MLI performance over a much wider temperature range with independently controlled boundary conditions. The calorimeter is also suitable for performing a variety of radiation heat transfer experiments including the determination of the temperature dependence of the total emissivity.

  16. Optimization of light collection scheme for forward hadronic calorimeter for STAR experiment at RHIC

    NASA Astrophysics Data System (ADS)

    Sergeeva, Maria

    2013-10-01

    We present the results of the optimization of a light collection scheme for a prototype of a sampling compensated hadronic calorimeter for upgrade of the STAR detector at RHIC (BNL). The absolute light yield and uniformity of light collection were measured with the full scale calorimeter tower for different types of reflecting materials, realistic mechanical tolerances for tower assembly and type of coupling between WLS bars and photo detectors. Measurements were performed with conventional PMTs and silicone photo multipliers. The results of these measurements were used to evaluate the influence of the optical collection scheme on the response of the calorimeter using GEANT4 MC. A large prototype of this calorimeter is presently under construction with the beam test scheduled early next year at FNAL.

  17. The electromagnetic calorimeter for the solenoidal tracker at RHIC. A Conceptual Design Report

    SciTech Connect

    Beddo, M.E.; Bielick, E.; Dawson, J.W.; The STAR EMC Collaboration

    1993-09-22

    This report discusses the following on the electromagnetic calorimeter for the solenoidal tracker at RHIC: conceptual design; the physics of electromagnetic calorimetry in STAR; trigger capability; integration into STAR; and cost, schedule, manpower, and funding.

  18. Prototype tests for a highly granular scintillator-based hadron calorimeter

    NASA Astrophysics Data System (ADS)

    Krüger, K.; CALICE Collaboration

    2015-02-01

    Within the CALICE collaboration, several concepts for the hadronic calorimeter of a future linear collider detector are studied. After having demonstrated the capabilities of the measurement methods in "physics prototypes", the focus now lies on improving their implementation in"technological prototypes", that are scalable to the full linear collider detector. The Analog Hadron Calorimeter (AHCAL) concept is a sampling calorimeter of tungsten or steel absorber plates and plastic scintillator tiles read out by silicon photomultipliers as active material. In the AHCAL technological prototype, the front-end chips are integrated into the active layers of the calorimeter and are designed for minimal power consumption. The versatile electronics allows the prototype to be equipped with different types of scintillator tiles and SiPMs. The current status of the AHCAL engineering prototype is shown and recent beam test measurements as well as plans for future hadron beam tests with a larger prototype will be discussed.

  19. Experimental results and experience with the KfK-tritium-calorimeter

    SciTech Connect

    Kapulla, H.; Heine, R.

    1995-10-01

    For the tritium assay at the Tritium Laboratory Karlsruhe (TLK) which started operation in Nov.94 an isothermal shield calorimeter was built. The calibration of the calorimeter was performed with an electrically heated simulator covering the range between 1 mW and about 2 W. After the calibration tritium activities in four Amersham uranium getter containers were determined. The excellent reproducibility and high precision of the measurements with the KfK-calorimeter was shown. The tritium activity inventories could be determined with relative standard deviations from the average value of the order of 0.01% to 0.1% depending on the activity level. These results demonstrate the suitability of the KfK-calorimeter as a nondestructive method for a careful assay of tritium. 3 refs., 11 figs., 2 tabs.

  20. Study of the performance of a semi-digital hadronic calorimeter using Monte Carlo techniques

    NASA Astrophysics Data System (ADS)

    Elmahroug, Y.; Tellili, B.; Souga, C.

    2014-04-01

    The Particle Flow Algorithm is one of the main concepts that will be used to measure the energies of hadronic jets at a future International Linear Collider. This method requires a highly granular hadronic calorimeter to measure the energy of jets with a good precision. The Semi-Digital Hadronic Calorimeter using glass resistive plate chambers as sensitive medium is one of the hadronic calorimeters which is used in conjunction with the particle flow method. In this paper, the performance of Semi-Digital Hadronic Calorimeter using glass resistive plate chambers as active elements has been studied by using the GEANT4 simulations. Its main operational characteristics such as mean response and energy resolution have been examined.

  1. On the massless gap'' adjustment of detected energy for passive material in front of a calorimeter

    SciTech Connect

    Trost, H.J.

    1992-01-31

    I have designed a correction scheme for energy losses in passive material in front of a calorimeter based on the massless gap'' idea. I use a flexible geometry model of a calorimeter design for SDC outside of a solenoidal coil made of aluminium cylinders of adjustable thickness. The signal from the first radiation length of active calorimetry is scaled dependent on the incoming and observed energies of the shower. A reasonable recovery of the resolution of an unobstructed calorimeter is achieved using correction factors that depend only upon the total thickness of passive material. Thus a useful correction may be built into the hardware by increasing the amount of scintillator in the first radiation length of the active calorimeter. The distribution of correction factors determined event-by-event indicate that an additional dependence on the observed signal in the massless gap and total incident energy is clearly present.

  2. On the ``massless gap`` adjustment of detected energy for passive material in front of a calorimeter

    SciTech Connect

    Trost, H.J.

    1992-01-31

    I have designed a correction scheme for energy losses in passive material in front of a calorimeter based on the ``massless gap`` idea. I use a flexible geometry model of a calorimeter design for SDC outside of a solenoidal coil made of aluminium cylinders of adjustable thickness. The signal from the first radiation length of active calorimetry is scaled dependent on the incoming and observed energies of the shower. A reasonable recovery of the resolution of an unobstructed calorimeter is achieved using correction factors that depend only upon the total thickness of passive material. Thus a useful correction may be built into the hardware by increasing the amount of scintillator in the first radiation length of the active calorimeter. The distribution of correction factors determined event-by-event indicate that an additional dependence on the observed signal in the massless gap and total incident energy is clearly present.

  3. The Laser calibration of the ATLAS Tile Calorimeter during the LHC run 1

    DOE PAGES

    Abdallah, J.; Alexa, C.; Coutinho, Y. Amaral; ...

    2016-10-12

    This article describes the Laser calibration system of the ATLAS hadronic Tile Calorimeter that has been used during the run 1 of the LHC . First, the stability of the system associated readout electronics is studied. It is found to be stable with variations smaller than 0.6 %. Then, the method developed to compute the calibration constants, to correct for the variations of the gain of the calorimeter photomultipliers, is described. These constants were determined with a statistical uncertainty of 0.3 % and a systematic uncertainty of 0.2 % for the central part of the calorimeter and 0.5 % formore » the end-caps. Lastly, the detection and correction of timing mis-configuration of the Tile Calorimeter using the Laser system are also presented.« less

  4. A measurement of E/{pi} for a fast lead liquid argon calorimeter

    SciTech Connect

    Makowiecki, D.; Gordon, H.A.; Ma, H.; Murtagh, M.; Radeka, V.; Rahm, D.; Rescia, S.; Abrams, G.S.; Groom, D.E.; Kirsten, F.; Levi, M.; Siegrist, J.; Amako, K.; Inaba, O.; Kondo, T.; Baden, A.R.; Fong, D.; Hadley, N.; Kunori, S.; Skuja, A.; Bowen, T.; Forden, G.; Jenkins, E.; Johns, K.; Rutherfoord, J.; Shupe, M.; Burnett, T.; Cook, V.; Davisson, R.; Mockett, P.; Rothberg, J.; Williams, R.W.; Cremaldi, L.; Reidy, J.; Summers, D.; DiGiacomo, N.; Draper, P.; Ferbel, T.; Lobkowicz, F.; Faust, J.; Hauptman, J.; Pang, M.; Gabriel, T.A.; Hagopian, V.; Womersley, J.; Handler, T.; Hitlin, D.; Mulholland, G.T.; Watanabe, Y.; Weerts, H.

    1990-12-31

    The NA34 (HELIOS) calorimeter has measured e/{pi} {congruent} 1.1 in a uranium/liquid argon calorimeter with a shaping time of 135 nsec. Lead may be a viable alternative, but e/{pi} must first be measured at fast shaping times in lead. We re preparing to measure e/{pi} at momenta ranging from 0.5 to 20 GeV/c and with shaping times of 50, 100 and 150 nsec.

  5. The SOUDAN 2 detector The design and construction of the tracking calorimeter modules

    NASA Astrophysics Data System (ADS)

    Allison, W. W. M.; Alner, G. J.; Ambats, I.; Ayres, D. S.; Balka, L. J.; Barr, G. D.; Barrett, W. L.; Benjamin, D.; Bode, C.; Border, P. M.; Brooks, C. B.; Cobb, J. H.; Cockerill, D. J. A.; Coover, K.; Cotton, R. J.; Courant, H.; Dahlin, B. B.; DasGupta, U.; Dawson, J. W.; Demuth, D. M.; Edwards, V. W.; Ewen, B.; Fields, T. H.; Garcia-Garcia, C.; Gallagher, H. M.; Giles, R. H.; Giller, G. L.; Goodman, M. C.; Gray, R. N.; Heppelmann, S.; Hill, N.; Hoftiezer, J. H.; Jankowski, D. J.; Johns, K.; Joyce, T.; Kafka, T.; Kasahara, S. M. S.; Kirby-Gallagher, L. M.; Kochocki, J.; Leeson, W.; Litchfield, P. J.; Longley, N. P.; Lopez, F. V.; Lowe, M. J.; Mann, W. A.; Marshak, M. L.; May, E. N.; Maxam, D.; McMaster, L.; Milburn, R.; Miller, W. H.; Minor, C. P.; Mondal, N.; Mualem, L.; Napier, A.; Nelson, E. M.; Nickson, R.; Oliver, W.; Pearce, G. F.; Perkins, D. H.; Peterson, E. A.; Price, L. E.; Roback, D. M.; Rosen, D. B.; Ruddick, K.; Saitta, B.; Schmid, D. J.; Schlereth, J.; Schneps, J.; Schub, M. H.; Seidlein, R. V.; Shield, P. D.; Shupe, M. A.; Spear, S.; Stassinakis, A.; Sundaralingam, N.; Thomson, M. A.; Thron, J. L.; Vassiliev, V.; Villaume, G.; Wakely, S. P.; Wall, D.; Wallis, E. W. G.; Weems, L.; Werkema, S. J.; West, N.; Wielgosz, U.; Woods, C. A.; Yarker, S.

    1996-02-01

    SOUDAN 2 is a 960-ton tracking calorimeter which has been constructed to search for nucleon decay and other phenomena. The full detector consists of 224 calorimeter modules each weighing 4.3 tons. The design and construction of the modules are described. The modules consist of finely segmented iron instrumented with 1 m long drift tubes of 15 mm internal diameter. The tubes enable three spatial coordinates and d E/d x to be recorded for charged particles traversing the tubes.

  6. Hadronic Shower Validation Experience for the ATLAS End-Cap Calorimeter

    SciTech Connect

    Kiryunin, A. E.; Salihagic, D.

    2007-03-19

    Validation of GEANT4 hadronic physics models is carried out by comparing experimental data from beam tests of modules of the ATLAS end-cap calorimeters with GEANT4 based simulations. Two physics lists (LHEP and QGSP) for the simulation of hadronic showers are evaluated. Calorimeter performance parameters like the energy resolution and response for charged pions and shapes of showers are studied. Comparison with GEANT3 predictions is done as well.

  7. A measurement of E/. pi. for a fast lead liquid argon calorimeter

    SciTech Connect

    Makowiecki, D.; Gordon, H.A.; Ma, H.; Murtagh, M.; Radeka, V.; Rahm, D.; Rescia, S. ); Abrams, G.S.; Groom, D.E.; Kirsten, F.; Levi, M.; Siegrist, J. ); Amako, K.; Inaba, O.; Kondo, T. ); Baden, A.R.; Fong, D.; Hadley, N.; Kunori, S.; Skuja, A. (Maryland U

    1990-01-01

    The NA34 (HELIOS) calorimeter has measured e/{pi} {congruent} 1.1 in a uranium/liquid argon calorimeter with a shaping time of 135 nsec. Lead may be a viable alternative, but e/{pi} must first be measured at fast shaping times in lead. We re preparing to measure e/{pi} at momenta ranging from 0.5 to 20 GeV/c and with shaping times of 50, 100 and 150 nsec.

  8. Radiation hardness of 3HF-tile/O2-WLS-fiber calorimeter

    SciTech Connect

    Han, S.W.; Hu, L.D.; Liu, N.Z.

    1993-11-01

    The radiation hardness of a 3HF-tile/O2-WLS-fiber calorimeter with two different tile/fiber patterns has been studied. Two calorimeter modules were irradiated up to 10 Mrad with the BEPC 1.3 GeV electron beam. The radiation damage of these modules is compared with our previous measurements from SCSN81-tile/BCF91A-WLS-fiber modules. The longitudinal damage profiles are fitted as a function of depth.

  9. PbWO4 crystals for the CMS electro-magnetic calorimeter

    NASA Astrophysics Data System (ADS)

    Organtini, Giovanni

    1997-02-01

    In this paper results obtained by the CMS collaboration in the study of the properties of PbWO4 crystals chosen to construct the electro-magnetic calorimeter for the CMS experiment at LHC are reported. The main activities carried out by the collaboration during 1995/1996 were devoted to the definition of the properties of the crystals needed to fully characterise them for the final calorimeter assembly.

  10. PbWO 4 crystals for the CMS electro-magnetic calorimeter

    NASA Astrophysics Data System (ADS)

    Organtini, Giovanni; CMS Collaboration

    1998-02-01

    In this paper results obtained by the CMS collaboration in the study of the properties of PbWO 4 crystals chosen to construct the electro-magnetic calorimeter for the CMS experiment at LHC are reported. The main activities carried out by the collaboration during 1995/1996 were devoted to the definition of the properties of the crystals needed to fully characterise them for the final calorimeter assembly.

  11. WE-G-17A-06: A Water Calorimeter for Use in MRI Linacs

    SciTech Connect

    De Prez, L; De Pooter, J; Jansen, B

    2014-06-15

    Purpose: At VSL, Dutch Metrology Institute, a new water calorimeter was developed with the purpose to replace the existing primary standard for absorbed dose to water in the Netherlands. The new water calorimeter is designed to be operable in medium- to high energy photon beams, electrons, protons as well as MRI integrated linear accelerators. VSL has operated a water calorimeter since 2001. This calorimeter formed the basis for the NCS-18 dosimetry protocol, which is commonly applied by medical physicists in the Netherlands and Belgium. Methods: The unit Gray is the unit of interest for measurement of the absorbed dose to water. Water calorimetry involves the measurement of a small temperature rise (0.24 mK/Gy) with an uncertainty of less than 1 μK/Gy at a temperature of 4 °C. Using extensive multi-physics simulations the new calorimeter's thermal performance was simulated before it was constructed at the end of 2013. With the advent of radiotherapy treatment units incorporating MR imaging the performance of the thermistor temperature sensors were characterized in a 1.5 T magnetic field. Results: A change of thermistor resistance was observed of less than 0.004% as a Result of the magneto-resistance effect in a 1.5 T magnetic field. Although a magneto-resistance effect was detectable, the effect on the temperature response in the water calorimeter was found to be negligible. Conclusion: With the realization of the new calorimeter operable in MRI linacs and designed for use in a variety of beam modalities, VSL is ready for accurate dosimetry in new advanced radiotherapy modalities. Due to the small form factor the calorimeter can be used on location in the actual therapy beam inside a 68 cm linac bore. This work was supported by EMRP grant HLT06. The EMRP is jointly funded by the EMRP participating countries within EURAMET and the European Union.

  12. Recombinant expression of Toluene o-Xylene Monooxygenase (ToMO) from Pseudomonas stutzeri OX1 in the marine Antarctic bacterium Pseudoalteromonas haloplanktis TAC125.

    PubMed

    Siani, Loredana; Papa, Rosanna; Di Donato, Alberto; Sannia, Giovanni

    2006-11-10

    The psychrophilic bacterium Pseudoalteromonas haloplanktis TAC125, isolated from Antarctic seawater, was used as recipient for a biodegradative gene of the mesophilic Pseudomonas stutzeri OX1. tou cluster, coding for Toluene o-Xylene Monooxygenase (ToMO), was successfully cloned and expressed into a "cold expression" vector. Apparent catalytic parameters of the recombinant microorganisms on three different substrates were determined and compared with those exhibited by Escherichia coli recombinant cells expressing ToMO. Production of a catalytically efficient TAC/tou microorganism supports the possibility of developing specific degradative capabilities for the bioremediation of chemically contaminated marine environments and of industrial effluents characterised by low temperatures.

  13. Cesium Iodide Crystal Calorimeter of the Proton Computed Tomography (pCT) Imager

    NASA Astrophysics Data System (ADS)

    Missaghian, Jessica; Sadrozinski, Hartmut; Colby, Brian; Rykalin, Victor; Hurley, Ford

    2009-11-01

    Researchers at SCIPP, LLMU and NIU have collaborated to make a functioning proton imager. Proton Computed Tomography (pCT) is designated to be applied in proton therapy of human cancer systems. It will image head-sized phantom objects and provide excellent space and energy resolution using a silicon microstrip tracker and crystal calorimetry. The residual energy could be measured with precision of a few percent using a Cesium Iodide crystal calorimeter. A single element of the CsI(TI) calorimeter was tested in order to understand the behavior of the future calorimeter system. We present test results on a CsI(TI) calorimeter element with proton beams of 35, 100 and 200MeV. The detector element was designed to comply with the demands of high energy resolution of a few percent and a dynamic range of two orders of magnitude (1-300MeV) under a counting rate of 10 kHz per channel. We also report on cosmic measurement results of each crystal of the future calorimeter matrix. A detailed description of the calorimeter data acquisition system will be given.

  14. Monte Carlo Simulation Study of a Differential Calorimeter Measuring the Nuclear Heating in Material Testing Reactors

    NASA Astrophysics Data System (ADS)

    Amharrak, H.; Reynard-Carette, C.; Lyoussi, A.; Carette, M.; Brun, J.; De Vita, C.; Fourmentel, D.; Villard, J.-F.; Guimbal, P.

    2016-02-01

    The nuclear heating measurements in Material Testing Reactors (MTRs) are crucial for the study of nuclear materials and fuels under irradiation. The reference measurements of this nuclear heating are especially performed by a differential calorimeter including a graphite sample material. Then these measurements are used for other materials, other geometries, or other experimental conditions in order to predict the nuclear heating and thermal conditions induced in the irradiation devices. This paper will present new simulations with MCNP Monte-Carlo transport code to determine the gamma heating profile inside the calorimeter. The whole complex geometry of the sensor has been considered. We use as an input source in the model, the photon spectra calculated in various positions of CARMEN-1 irradiation program in OSIRIS reactor. After a description of the differential calorimeter device, the MCNP modeling used for the calculations of radial profile of nuclear heating inside the calorimeter elements will be introduced. The obtained results of different simulations will be detailed and discussed in this paper. The charged particle equilibrium inside the calorimeter elements will be studied. Then we will focus on parametric studies of the various components of the calorimeter. The influence of source type will be also took into account. Moreover the influence of the material used for the sample will be described.

  15. Fire tests and analyses of a rail cask-sized calorimeter.

    SciTech Connect

    Figueroa, Victor G.; Lopez, Carlos; Suo-Anttila, Ahti Jorma; Greiner, Miles

    2010-10-01

    Three large open pool fire experiments involving a calorimeter the size of a spent fuel rail cask were conducted at Sandia National Laboratories Lurance Canyon Burn Site. These experiments were performed to study the heat transfer between a very large fire and a large cask-like object. In all of the tests, the calorimeter was located at the center of a 7.93-meter diameter fuel pan, elevated 1 meter above the fuel pool. The relative pool size and positioning of the calorimeter conformed to the required positioning of a package undergoing certification fire testing. Approximately 2000 gallons of JP-8 aviation fuel were used in each test. The first two tests had relatively light winds and lasted 40 minutes, while the third had stronger winds and consumed the fuel in 25 minutes. Wind speed and direction, calorimeter temperature, fire envelop temperature, vertical gas plume speed, and radiant heat flux near the calorimeter were measured at several locations in all tests. Fuel regression rate data was also acquired. The experimental setup and certain fire characteristics that were observed during the test are described in this paper. Results from three-dimensional fire simulations performed with the Cask Analysis Fire Environment (CAFE) fire code are also presented. Comparisons of the thermal response of the calorimeter as measured in each test to the results obtained from the CAFE simulations are presented and discussed.

  16. Evaluation of the Argonne National Laboratory servo-controlled calorimeter system

    SciTech Connect

    Foster, L.A.

    1997-01-01

    The control system of a replacement mode, twin-bridge, water-bath calorimeter originally built by Mound EG&G Applied Technologies was modified by Argonne National Laboratory. The calorimeter was upgraded with a PC-based computer control and data acquisition system. The system was redesigned to operate in a servo-control mode, and a preheater was constructed to allow pre-equilibration of samples. The instrument was sent to the Plutonium Facility at Los Alamos National Laboratory for testing and evaluation of its performance in the field using heat source standards and plutonium process materials. The important parameters for calorimeter operation necessary to satisfy the nuclear materials control and accountability requirements of the Plutonium Facility were evaluated over a period of several months. These parameters include calorimeter stability, measurement precision and accuracy, and average measurement time. The observed measurement precision and accuracy were found to be acceptable for most accountability measurements, although they were slightly larger than the values for calorimeters in routine use at the Plutonium Facility. Average measurement times were significantly shorter than measurement times for identical items in the Plutonium Facility calorimeters. Unexplained shifts in the baseline measurements were observed on numerous occasions. These shifts could lead to substantial measurement errors if they are not very carefully monitored by the operating facility. Detailed results of the experimental evaluation are presented in this report.

  17. El Salvador, 13 January and SEA-TAC, 28 February: Two recent examples of "snappy" intraplate earthquakes

    NASA Astrophysics Data System (ADS)

    OKAL, E. A.; Kirby, S. H.

    2001-05-01

    The two recent damaging earthquakes in El Salvador (13 January) and in the Seattle-Tacoma area (28 February, hereafter "SEA-TAC") do not express relative motion at a plate boundary contact, but rather are examples of normal faulting events occurring inside the downgoing slab. Similar events have included the Oaxaca earthquake of 30 September 1999, the shock in the Central Valley of Chile on 15 October 1997, as well as the large event farther South on 25 January 1939. In previous studies, we had applied the formalism of the energy-to-moment ratio introduced by Newman and Okal [1998] to this class of events, and found that the parameter THETA = log (E/M sub 0 ) characterizing the repartition of energy between high and low frequencies, was as much as a full unit greater than expected from scaling laws (-4.90), meaning that the seismic source spectrum is biased towards high frequencies, resulting in a possibly faster, more "snappy" moment release than predicted by global scaling laws. As a result, this effect canoffset the generally greater hypocentral depth of the intraslab events, and result in higher levels of accelerations in the near-field, and consequently in more severe damage, reaching catastrophic proportions for the 1939 Chilean event. Because of their generally lower magnitudes, intraslab earthquakes may recur more often than the large "mega-thrust" events, and thus be a significant, possibly the primary, contributor to seismic risk in the relevant geographical areas [S.H. Kirby, Fall 1999 AGU meeting]. As of the time of writing, preliminary average THETA values are -4.79 for the El Salvador event, and -4.54 for the SEA-TAC earthquake. The former can thus be regarded as mildly fast, and comparable in this respect to the Oaxaca event of 30 September 1999. While not reaching the values observed in Chile (-4.0), the THETA value for the SEA-TAC earthquake qualifies the event as definitely "fast". We will present refined computations, including a reassessment of

  18. TAC BRAWLER - An application of engagement simulation modeling to simulator visual system display requirements for air combat maneuvering

    NASA Technical Reports Server (NTRS)

    Kerchner, R. M.; Hughes, R. G.; Lee, A.

    1984-01-01

    The TAC BRAWLER air combat simulation models both the acquisition and use of visual information by the pilot. It was used to provide the designers of manned simulators for air-to-air combat with information regarding the training implications of display system resolution, inherent target contrast, field of view, and transport delay. Various display designs were simulated, and the resulting quantitative and qualitative differences in engagements were considered indicators of possible mistraining. Display resolution was found to alter combats primarily through its effect on detection ranges; the 'pixel averaging' contrast management technique was shown to largely compensate for this problem. Transport delay significantly degrades pilot tracking ability, but the training impact of the effect is unclear.

  19. Cylindrical boiloff calorimeters for testing of thermal insulation systems

    NASA Astrophysics Data System (ADS)

    Fesmire, J. E.; Johnson, W. L.; Meneghelli, B. J.; Coffman, B. E.

    2015-12-01

    Cryostats have been developed and standardized for laboratory testing of thermal insulation systems in a cylindrical configuration. Boiloff calorimetry is the measurement principle for determining the effective thermal conductivity (ke) and heat flux (q) of a test specimen at a fixed environmental condition (boundary temperatures, cold vacuum pressure, and residual gas composition). Through its heat of vaporization, liquid nitrogen serves as the energy meter, but the design is adaptable for various cryogens. The main instrument, Cryostat-100, is thermally guarded and directly measures absolute thermal performance. A cold mass assembly and all fluid and instrumentation feedthroughs are suspended from a lid of the vacuum canister; and a custom lifting mechanism allows the assembly and specimen to be manipulated easily. Each of three chambers is filled and vented through a single feedthrough for minimum overall heat leakage. The cold mass design precludes direct, solid-conduction heat transfer (other than through the vessel's outer wall itself) from one liquid volume to another, which is critical for achieving very low heat measurements. The cryostat system design details and test methods are discussed, as well as results for select thermal insulation materials. Additional cylindrical boiloff calorimeters and progress toward a liquid hydrogen apparatus are also discussed.

  20. The New APD Based Readout for the Crystal Barrel Calorimeter

    NASA Astrophysics Data System (ADS)

    Urban, M.; Honisch, Ch; Steinacher, M.; CBELSA/TAPS Collaboration

    2015-02-01

    The CBELSA/TAPS experiment at ELSA measures double polarization observables in meson photoproduction off protons and neutrons. To be able to measure purely neutral reactions off polarized neutrons with high efficiency, the main calorimeter has to be integrated into the first level trigger. This requires to exchange the existing PIN photo diode by a new avalanche photo diode (APD) readout. The newly developed readout electronics will provide an energy resolution compatible to the previous set-up and a fast trigger signal down to 10 MeV energy deposit per crystal. After the successful final tests with a 3x3 CsI crystal matrix in Bonn at ELSA and in Mainz at MAMI all front-end electronics were produced in fall 2013. Automated test routines for the front-end electronics were developed and the characterization measurements of all APDs were successfully accomplished in Bonn. The project is supported by the Deutsche Forschungsgemeinschaft (SFB/TR16) and Schweizerischer Nationalfonds.

  1. On the Challenge of Keeping ATLAS Tile Calorimeter Raw Data

    NASA Astrophysics Data System (ADS)

    Tsiskaridze, V. K.

    2012-08-01

    The Tile Calorimeter (TileCal) for the ATLAS experiment at the CERN Large Hadron Collider (LHC) is currently taking data with proton-proton collisions. The TileCal read-out system was initially designed to reconstruct the data in real-time and to store for each channel the signal amplitude, time and quality factor at the required high rate. This approach implied discarding 80% of the raw data that correspond to noise or small signals. Practical experience operating in this scheme with increasing rate have led to several modifications and understanding that some kind of data compression is helpful during data processing and storing. An alternate approach is to use online reconstruction for Level 2 triggering only and to implement a data flow lossless compression scheme for further offiine analysis. A new version of the lossless compression algorithm is proposed which allows to both save the complete raw data and to feed the trigger with the reconstructed signal amplitude and time. It does not increase the data flow as compared to the existing approach and the size of the data fragments transmitted is more stable. We will describe the lossless compression algorithm as a possible upgrade of the Tile data acquisition and highlight some details of the implementation. We will report on its testing and validation and on the overall performance measured on high rate tests, calibration and √ {s} = 7 TeV proton-proton collisions runs.

  2. [Calorimeter based detectors for high energy hadron colliders]. [Progress report

    SciTech Connect

    Not Available

    1992-08-04

    This document provides a progress report on research that has been conducted under DOE Grant DEFG0292ER40697 for the past year, and describes proposed work for the second year of this 8 year grant starting November 15, 1992. Personnel supported by the contract include 4 faculty, 1 research faculty, 4 postdocs, and 9 graduate students. The work under this grant has in the past been directed in two complementary directions -- DO at Fermilab, and the second SSC detector GEM. A major effort has been towards the construction and commissioning of the new Fermilab Collider detector DO, including design, construction, testing, the commissioning of the central tracking and the central calorimeters. The first DO run is now underway, with data taking and analysis of the first events. Trigger algorithms, data acquisition, calibration of tracking and calorimetry, data scanning and analysis, and planning for future upgrades of the DO detector with the advent of the FNAL Main Injector are all involved. The other effort supported by this grant has been towards the design of GEM, a large and general-purpose SSC detector with special emphasis on accurate muon measurement over a large solid angle. This effort will culminate this year in the presentation to the SSC laboratory of the GEM Technical Design Report. Contributions are being made to the detector design, coordination, and physics simulation studies with special emphasis on muon final states. Collaboration with the RD5 group at CERN to study muon punch through and to test cathode strip chamber prototypes was begun.

  3. High frequency alternating current chip nano calorimeter with laser heating

    SciTech Connect

    Shoifet, E.; Schick, C.; Chua, Y. Z.; Huth, H.

    2013-07-15

    Heat capacity spectroscopy at frequencies up to 100 kHz is commonly performed by thermal effusivity measurements applying the 3ω-technique. Here we show that AC-calorimetry using a thin film chip sensor allows for the measurement of frequency dependent heat capacity in the thin film limit up to about 1 MHz. Using films thinner than the thermal length of the thermal wave (∼1 μm) at such frequencies is advantageous because it provides heat capacity alone and not in combination with other quantities like thermal conductivity, at least on a qualitative basis. The used calorimetric sensor and the sample are each less than 1 μm thick. For high frequency AC-calorimetry, high cooling rates at very small temperature differences are required. This is realized by minimizing the heated spot to the size of the on chip thermocouple (3 × 6 μm{sup 2}). A modulated laser beam shaped and positioned by a glass fiber is used as the heat source. The device was used to measure the complex heat capacity in the vicinity of the dynamic glass transition (structural relaxation) of poly(methyl methacrylate). Combining different calorimeters finally provides data between 10{sup −3} Hz and 10{sup 6} Hz. In this frequency range the dynamic glass transition shifts about 120 K.

  4. Calibration of the CMS electromagnetic calorimeter with LHC collision data

    NASA Astrophysics Data System (ADS)

    Obertino, M. M.; CMS Collaboration

    2013-08-01

    The CMS ECAL is a high resolution electromagnetic calorimeter which relies upon precision calibration in order to achieve and maintain its design performance. Variations in light collected from the lead tungstate crystals, due to intrinsic differences in crystals/photodetectors, as well as variations with time due to radiation damage for example, need to be taken into account. Sophisticated and effective methods of inter-crystal and absolute calibration have been devised, using collision data from the 2011 LHC run and a dedicated light injection system. For inter-calibration, low mass particle (π0 and η) decays to two photons are exploited, as well as the azimuthal symmetry of the average energy deposition at a given pseudorapidity. The light injection system monitors the channel response in real-time and enables the re-calibration of the measured energies over time. This is cross-checked by the comparison of E/p measurements of electrons from W decays (where the momentum is measured in the CMS tracker) with/without these re-calibrations applied. Absolute calibration has been performed using Z decays into electron-positron pairs.

  5. Development of Metallic Magnetic Calorimeters with a Critical Temperature Switch

    NASA Astrophysics Data System (ADS)

    Kim, S. R.; Choi, J.; Jo, H. S.; Kang, C. S.; Kim, G. B.; Kim, H. L.; Kim, I. W.; Lee, H. J.; Lee, J. H.; Lee, M. K.; Oh, S. Y.; Sala, E.; So, J. H.; Yoon, W. S.; Kim, Y. H.

    2016-07-01

    We report on the progress in the development of meander-shaped metallic magnetic calorimeters (MMCs) with a critical temperature switch. A niobium meander-shaped coil in an MMC is arranged to form a superconducting loop. It is to measure the change in magnetization and to apply a persistent current that magnetizes the MMC sensor material. In this work, part of the superconducting loop is fabricated with another superconducting material with its transition temperature (T_C) lower than that of niobium. A persistent current can be injected in the loop while reducing the temperature from above to below the T_C of the switch. Aluminum (Al) wires and an alloy of molybdenum and germanium (MoGe) were tested as critical temperature switch. The test with the Al switch demonstrated the temperature switch concept for meander-shaped MMCs that require a large field current. Microfabricated MoGe switches showed a T_C near 4.3 K, but only 7 mA of persistent current could be charged due to MoGe film discontinuity. This issue requires further improvement in the fabrication procedure.

  6. High frequency alternating current chip nano calorimeter with laser heating.

    PubMed

    Shoifet, E; Chua, Y Z; Huth, H; Schick, C

    2013-07-01

    Heat capacity spectroscopy at frequencies up to 100 kHz is commonly performed by thermal effusivity measurements applying the 3ω-technique. Here we show that AC-calorimetry using a thin film chip sensor allows for the measurement of frequency dependent heat capacity in the thin film limit up to about 1 MHz. Using films thinner than the thermal length of the thermal wave (~1 μm) at such frequencies is advantageous because it provides heat capacity alone and not in combination with other quantities like thermal conductivity, at least on a qualitative basis. The used calorimetric sensor and the sample are each less than 1 μm thick. For high frequency AC-calorimetry, high cooling rates at very small temperature differences are required. This is realized by minimizing the heated spot to the size of the on chip thermocouple (3 × 6 μm(2)). A modulated laser beam shaped and positioned by a glass fiber is used as the heat source. The device was used to measure the complex heat capacity in the vicinity of the dynamic glass transition (structural relaxation) of poly(methyl methacrylate). Combining different calorimeters finally provides data between 10(-3) Hz and 10(6) Hz. In this frequency range the dynamic glass transition shifts about 120 K.

  7. High frequency alternating current chip nano calorimeter with laser heating

    NASA Astrophysics Data System (ADS)

    Shoifet, E.; Chua, Y. Z.; Huth, H.; Schick, C.

    2013-07-01

    Heat capacity spectroscopy at frequencies up to 100 kHz is commonly performed by thermal effusivity measurements applying the 3ω-technique. Here we show that AC-calorimetry using a thin film chip sensor allows for the measurement of frequency dependent heat capacity in the thin film limit up to about 1 MHz. Using films thinner than the thermal length of the thermal wave (˜1 μm) at such frequencies is advantageous because it provides heat capacity alone and not in combination with other quantities like thermal conductivity, at least on a qualitative basis. The used calorimetric sensor and the sample are each less than 1 μm thick. For high frequency AC-calorimetry, high cooling rates at very small temperature differences are required. This is realized by minimizing the heated spot to the size of the on chip thermocouple (3 × 6 μm2). A modulated laser beam shaped and positioned by a glass fiber is used as the heat source. The device was used to measure the complex heat capacity in the vicinity of the dynamic glass transition (structural relaxation) of poly(methyl methacrylate). Combining different calorimeters finally provides data between 10-3 Hz and 106 Hz. In this frequency range the dynamic glass transition shifts about 120 K.

  8. Demonstration of Time Domain Multiplexed Readout for Magnetically Coupled Calorimeters

    NASA Technical Reports Server (NTRS)

    Porst, J.-P.; Adams, J. S.; Balvin, M.; Bandler, S.; Beyer, J.; Busch, S. E.; Drung, D.; Seidel, G. M.; Smith, S. J.; Stevenson, T. R.

    2012-01-01

    Magnetically coupled calorimeters (MCC) have extremely high potential for x-ray applications due to the inherent high energy resolution capability and being non-dissipative. Although very high energy-resolution has been demonstrated, until now there has been no demonstration of multiplexed read-out. We report on the first realization of a time domain multiplexed (TDM) read-out. While this has many similarities with TDM of transition-edge-sensors (TES), for MGGs the energy resolution is limited by the SQUID read-out noise and requires the well established scheme to be altered in order to minimize degradation due to noise aliasing effects. In cur approach, each pixel is read out by a single first stage SQUID (SQ1) that is operated in open loop. The outputs of the SQ1 s are low-pass filtered with an array of low cross-talk inductors, then fed into a single-stage SQUID TD multiplexer. The multiplexer is addressed from room temperature and read out through a single amplifier channel. We present results achieved with a new detector platform. Noise performance is presented and compared to expectations. We have demonstrated multiplexed X-ray spectroscopy at 5.9keV with delta_FWHM=10eV. In an optimized setup, we show it is possible to multiplex 32 detectors without significantly degrading the Intrinsic detector resolution.

  9. Modified Differential Scanning Calorimeter for Direct Electrocaloric Measurements.

    PubMed

    Sanlialp, Mehmet; Molin, Christian; Shvartsman, Vladimir V; Gebhardt, Sylvia; Lupascu, Doru C

    2016-10-01

    Solid-state refrigeration using the electrocaloric effect (ECE) in ferroelectric materials is a promising alternative to the conventional vapor-compression technology. In spite of growing interest to the investigation of the ECE, direct measurements of the effect are still rare. In this paper, we report on a modification of a differential scanning calorimeter for direct ECE measurements. The importance of proper estimation of the thermal correction factor and use of proper values of the heat capacitance for correct ECE measurements is discussed. The ECE measurements were performed for Ba(Zr0.2Ti0.8)O3 and Ba(Zr0.12Ti0.88)O3 bulk ceramics. Large electrocaloric temperature changes of 0.54 and 0.34 K are achieved under the application of an electric field of 2 kV/mm for the Ba(Zr0.12Ti0.88)O3 and Ba(Zr0.2Ti0.8)O3 samples, respectively. The relation between the directly measured ECE values and frequently used indirect estimation based on Maxwell's relations is discussed.

  10. The CMS Level-1 Calorimeter Trigger for LHC Run II

    NASA Astrophysics Data System (ADS)

    Sinthuprasith, Tutanon

    2017-01-01

    The phase-1 upgrades of the CMS Level-1 calorimeter trigger have been completed. The Level-1 trigger has been fully commissioned and it will be used by CMS to collect data starting from the 2016 data run. The new trigger has been designed to improve the performance at high luminosity and large number of simultaneous inelastic collisions per crossing (pile-up). For this purpose it uses a novel design, the Time Multiplexed Design, which enables the data from an event to be processed by a single trigger processor at full granularity over several bunch crossings. The TMT design is a modular design based on the uTCA standard. The architecture is flexible and the number of trigger processors can be expanded according to the physics needs of CMS. Intelligent, more complex, and innovative algorithms are now the core of the first decision layer of CMS: the upgraded trigger system implements pattern recognition and MVA (Boosted Decision Tree) regression techniques in the trigger processors for pT assignment, pile up subtraction, and isolation requirements for electrons, and taus. The performance of the TMT design and the latency measurements and the algorithm performance which has been measured using data is also presented here.

  11. Tic-Tac-Toe Binary Lattices from the Interfacial Self-Assembly of Branched and Spherical Nanocrystals.

    PubMed

    Castelli, Andrea; de Graaf, Joost; Prato, Mirko; Manna, Liberato; Arciniegas, Milena P

    2016-04-26

    The self-organization of nanocrystals has proven to be a versatile route to achieve increasingly sophisticated structures of materials, where the shape and properties of individual particles impact the final functionalities. Recent works have addressed this topic by combining various shapes to achieve more complex arrangements of particles than are possible in single-component samples. However, the ability to create intricate architectures over large regions by exploiting the shape of multiply branched nanocrystals to host a second component remains unexplored. Here, we show how the concave shape of a branched nanocrystal, the so-called octapod, is able to anchor a sphere. The two components self-assemble into a locally ordered monolayer consisting of an intercalated square lattice of octapods and spheres, which is reminiscent of the "tic-tac-toe" game. These tic-tac-toe domains form through an interfacial self-assembly that occurs by the dewetting of a hexane layer containing both particle types. By varying the experimental conditions and performing molecular dynamics simulations, we show that the ligands coating the octapods are crucial to the formation of this structure. We find that the tendency of an octapod to form an interlocking-type structure with a second octapod strongly depends on the ligand shell of the pods. Breaking this tendency by ligand exchange allows the octapods to assemble into a more relaxed configuration, which is able to form a lock-and-key-type structure with a sphere, when they have a suitable size ratio. Our findings provide an example of a more versatile use of branched nanocrystals in self-assembled functional materials.

  12. Surgical Treatment of Patients Enrolled in the National Registry of Genetically Triggered Thoracic Aortic Conditions (GenTAC)

    PubMed Central

    Song, Howard K.; Bavaria, Joseph E.; Kindem, Mark W.; Holmes, Kathryn W.; Milewicz, Dianna M.; Maslen, Cheryl L.; Pyeritz, Reed E.; Basson, Craig T.; Eagle, Kim; Tolunay, H. Eser; Kroner, Barbara L.; Dietz, Hal; Menashe, Victor; Devereux, Richard B.; Desvigne-Nickens, Patrice; Ravekes, William; Weinsaft, Jonathan W.; Brambilla, Donald; Stylianou, Mario P.; Hendershot, Tabitha; Mitchell, Megan S.; LeMaire, Scott A.

    2011-01-01

    Background Genetic disorders are an important cause of thoracic aortic aneurysms (TAAs) in young patients. Despite advances in the treatment of genetically triggered TAAs, the optimal syndrome-specific treatment approach remains undefined. We used data from the NIH-funded, multicenter National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC) to characterize the contemporary surgical treatment of patients with genetically triggered TAAs. Methods GenTAC’s aim is to collect longitudinal clinical data and banked biospecimens from 2800 patients with genetically triggered TAAs. We analyzed data from all patients enrolled in GenTAC to date whose clinical data were available (n=606; mean age, 37.5 years). Results The patients’ primary diagnoses included Marfan syndrome (35.8%), bicuspid aortic valve with aneurysm (29.2%), and familial TAAs and dissections (10.7%). More than half of patients (56.4%) had undergone at least 1 operation; the most common indications were aneurysm (85.7%), valve dysfunction (65.8%), and dissection (25.4%). Surgical procedures included replacement of the aortic root (50.6%), ascending aorta (64.8%), aortic arch (27.9%), and descending or thoracoabdominal aorta (12.4%). Syndrome-specific differences in age, indications for surgery, and procedure type were identified. Conclusions Patients with genetically transmitted TAAs evaluated in tertiary care centers frequently undergo surgery. Aneurysm repairs most commonly involve the aortic root and ascending aorta; distal repairs are less common. Like TAAs themselves, complications of TAAs, including dissection and aortic valve dysfunction, are important indications for surgery. Future studies will focus on syndrome- and gene-specific phenotypes, biomarkers, treatments, and outcomes to improve the treatment of patients with TAAs. PMID:19699898

  13. Building America Case Study: Ground Source Heat Pump Research, TaC Studios Residence, Atlanta, Georigia (Fact Sheet)

    SciTech Connect

    Not Available

    2014-09-01

    As part of the NAHB Research Center Industry Partnership, Southface partnered with TaC Studios, an Atlanta based architecture firm specializing in residential and light commercial design, on the construction of a new test home in Atlanta, GA in the mixed-humid climate. This home serves as a residence and home office for the firm's owners, as well as a demonstration of their design approach to potential and current clients. Southface believes the home demonstrates current best practices for the mixed-humid climate, including a building envelope featuring advanced air sealing details and low density spray foam insulation, glazing that exceeds ENERGY STAR requirements, and a high performance heating and cooling system. Construction quality and execution was a high priority for TaC Studios and was ensured by a third party review process. Post construction testing showed that the project met stated goals for envelope performance, an air infiltration rate of 2.15 ACH50. The homeowner's wished to further validate whole house energy savings through the project's involvement with Building America and this long-term monitoring effort. As a Building America test home, this home was evaluated to detail whole house energy use, end use loads, and the efficiency and operation of the ground source heat pump and associated systems. Given that the home includes many non-typical end use loads including a home office, pool, landscape water feature, and other luxury features not accounted for in Building America modeling tools, these end uses were separately monitored to determine their impact on overall energy consumption.

  14. Structure design and enviromental test of BGO calorimeter for satellite DAMPE

    NASA Astrophysics Data System (ADS)

    Hu, Yiming; Feng, Changqing; Zhang, Yunlong; Chen, Dengyi; Chang, Jin

    2016-07-01

    The Dark Matter Particle Explorer, DAMPE, is a new designed satellite developed for the new Innovation 2020 program of Chinese Academy of Sciences. As the most important payload of China's first scientific satellite for detecting dark matter, the primary purposes of BGO calorimeter is to measure the energy of incident high energy electrons and gamma rays (5GeV-10TeV) and to identify hadron and electronics. BGO calorimeter also provides an important background discriminator by measuring the energy deposition due to the particle shower that produced by the e^{±}, γ and imaging their shower development profile. Structure design of BGO calorimeter is described in this paper. The new designed BGO calorimeter consists of 308 BGO crystals coupled with photomultiplier tubes on its two ends. The envelop size of the BGO calorimeter is 907.5mm×907.5mm×494.5mm,and the weight of which is 1051.4Kg. The most important purpose of mechanical design is how to package so heavy crystals into a detector as required arrangement and to make sure reliability and safety. This paper describes the results of vibration tests using the Flight Module of the BGO Calorimeter for the DAMPE satellite. During the vibration tests, no degradation of the mechanical assembly was observed. After random or sinusoidal vibrations, there was no significant changes of the frequency signatures observed during the modal surveys. The comparison of results of cosmic ray tests before and after the vibration shows no change in the performance of the BGO calorimeter.

  15. Using Tic-Tac Software to Reduce Anxiety-Related Behaviour in Adults with Autism and Learning Difficulties during Waiting Periods: A Pilot Study

    ERIC Educational Resources Information Center

    Campillo, Cristina; Herrera, Gerardo; Remírez de Ganuza, Conchi; Cuesta, José L.; Abellán, Raquel; Campos, Arturo; Navarro, Ignacio; Sevilla, Javier; Pardo, Carlos; Amati, Fabián

    2014-01-01

    Deficits in the perception of time and processing of changes across time are commonly observed in individuals with autism. This pilot study evaluated the efficacy of the use of the software tool Tic-Tac, designed to make time visual, in three adults with autism and learning difficulties. This research focused on applying the tool in waiting…

  16. TAC from Mycobacterium tuberculosis: a paradigm for stress-responsive toxin-antitoxin systems controlled by SecB-like chaperones.

    PubMed

    Sala, Ambre; Calderon, Virginie; Bordes, Patricia; Genevaux, Pierre

    2013-03-01

    Bacterial type II toxin-antitoxins (TAs) are two-component systems that modulate growth in response to specific stress conditions, thus promoting adaptation and persistence. The major human pathogen Mycobacterium tuberculosis potentially encodes 75 TAs and it has been proposed that persistence induced by active toxins might be relevant for its pathogenesis. In this work, we focus on the newly discovered toxin-antitoxin-chaperone (TAC) system of M. tuberculosis, an atypical stress-responsive TA system tightly controlled by a molecular chaperone that shows similarity to the canonical SecB chaperone involved in Sec-dependent protein export in Gram-negative bacteria. We performed a large-scale genome screening to reconstruct the evolutionary history of TAC systems and found that TAC is not restricted to mycobacteria and seems to have disseminated in diverse taxonomic groups by horizontal gene transfer. Our results suggest that TAC chaperones are evolutionary related to the solitary chaperone SecB and have diverged to become specialized toward their cognate antitoxins.

  17. Expression of rat I-TAC/CXCL11/SCYA11 during central nervous system inflammation: comparison with other CXCR3 ligands.

    PubMed

    McColl, Shaun R; Mahalingam, Surendran; Staykova, Maria; Tylaska, Laurie A; Fisher, Katherine E; Strick, Christine A; Gladue, Ronald P; Neote, Kuldeep S; Willenborg, David O

    2004-11-01

    The chemokines are a large gene superfamily with critical roles in development and immunity. The chemokine receptor CXCR3 appears to play a major role in the trafficking of activated Th1 lymphocytes. There are at least three major ligands for CXCR3: mig/CXCL9, IP-10/CXCL10 and I-TAC/CXCL11, and of these three ligands, CXCL11 is the least well-characterized. In this study, we have cloned a rat ortholog of CXCL11, evaluated its function, and examined its expression in the Th-1-mediated disease, experimental autoimmune encephalomyelitis (EAE) in the rat. Based on its predicted primary amino-acid sequence, rat I-TAC/CXCL11 was synthesized and shown to induce chemotaxis of activated rat T lymphocytes in vitro and the in vivo migration of T lymphocytes when injected into the skin. I-TAC/CXCL11 expression, as determined by RT-PCR, increased in lymph node and spinal cord tissue collected from rats in which EAE had been actively induced, and in spinal cord tissue from rats in which EAE had been passively induced. The kinetics of expression were similar to that of CXCR3 and IP-10/CXCL10, although expression of both CXCR3 and IP-10/CXCL10 was more intense than that of I-TAC/CXCL11 and increased more rapidly in both lymph nodes and the spinal cord. Only minor levels of expression of the related chemokine mig/CXCL9 were observed. Immunohistochemistry revealed that the major cellular source of I-TAC/CXCL11 in the central nervous system (CNS) during EAE is likely to be the astrocyte. Together, these data indicate that I-TAC/CXCL11 is expressed in the CNS during the clinical phase of EAE. However, the observation that I-TAC/CXCL11 is expressed after receptor expression is detected suggests that it is not essential for the initial migration of CXCR3-bearing cells into the CNS.

  18. Study on Radiation Condition in DAMPE Orbit by Analyzing the Engineering Data of BGO Calorimeter

    NASA Astrophysics Data System (ADS)

    Feng, Changqing; Liu, Shubin; Zhang, Yunlong; Ma, Siyuan

    2016-07-01

    The DAMPE (DArk Matter Particle Explorer) is a scientific satellite which was successfully launched into a 500 Km sun-synchronous orbit, on December 17th, 2015, from the Jiuquan Satellite Launch Center of China. The major scientific objectives of the DAMPE mission are primary cosmic ray, gamma ray astronomy and dark matter particles, by observing high energy primary cosmic rays, especially positrons/electrons and gamma rays with an energy range from 5 GeV to 10 TeV. The BGO calorimeter is a critical sub-detector of DAMPE payload, for measuring the energy of cosmic particles, distinguishing positrons/electrons and gamma rays from hadron background, and providing trigger information. It utilizes 308 BGO (Bismuth Germanate Oxide) crystal logs with the size of 2.5cm*2.5cm*60cm for each log, to form a total absorption electromagnetic calorimeter. All the BGO logs are stacked in 14 layers, with each layer consisting of 22 BGO crystal logs and each log is viewed by two Hamamatsu R5610A PMTs (photomultiplier tubes), from both sides respectively. In order to achieve a large dynamic range, each PMT base incorporates a three dynode (2, 5, 8) pick off, which results in 616 PMTs and 1848 signal channels. The readout electronics system, which consists of 16 FEE (Front End Electronics) modules, was developed. Its main functions are based on the Flash-based FPGA (Field Programmable Gate Array) chip and low power, 32-channel VA160 and VATA160 ASICs (Application Specific Integrated Circuits) for precisely measuring the charge of PMT signals and providing "hit" signals as well. The hit signals are sent to the trigger module of PDPU (Payload Data Process Unit) and the hit rates of each layer is real-timely recorded by counters and packed into the engineering data, which directly reflect the flux of particles which fly into or pass through the detectors. In order to mitigate the SEU (Single Event Upset) effect in radioactive space environment, certain protecting methods, such as TMR

  19. BOLD signal effects of transcranial alternating current stimulation (tACS) in the alpha range: A concurrent tACS-fMRI study.

    PubMed

    Vosskuhl, Johannes; Huster, René J; Herrmann, Christoph S

    2016-10-15

    Many studies have proven transcranial alternating current stimulation (tACS) to manipulate brain activity. Until now it is not known, however, how these manipulations in brain activity are represented in brain metabolism or how spatially specific these changes are. Alpha-tACS has been shown to enhance the amplitude of the individual alpha frequency (IAF) and a negative correlation between alpha amplitude and occipital BOLD signal was reported in numerous EEG/fMRI experiments. Thus, alpha-tACS was chosen to test the effects of tACS on the BOLD signal. A reduction thereof was expected during alpha-tACS which shows the spatial extent of tACS effects beyond modeling studies. Three groups of subjects were measured in an MRI scanner, receiving tACS at either their IAF (N=11), 1Hz (control; N=12) or sham (i.e., no stimulation - a second control; N=11) while responding to a visual vigilance task. Stimulation was administered in an interleaved pattern of tACS-on runs and tACS-free baseline periods. The BOLD signal was analyzed in response to tACS-onset during resting state and in response to seldom target stimuli. Alpha-tACS at 1.0mA reduced the task-related BOLD response to visual targets in the occipital cortex as compared to tACS-free baseline periods. The deactivation was strongest in an area where the BOLD signal was shown to correlate negatively with alpha amplitude. A direct effect of tACS on resting state BOLD signal levels could not be shown. Our findings suggest that tACS-related changes in BOLD activity occur only as a modulation of an existing BOLD response.

  20. Environmental test of the BGO calorimeter for DArk Matter Particle Explorer

    NASA Astrophysics Data System (ADS)

    Hu, Yi-Ming; Chang, Jin; Chen, Deng-Yi; Guo, Jian-Hua; Zhang, Yun-Long; Feng, Chang-Qing

    2016-11-01

    DArk Matter Particle Explorer (DAMPE) is the first Chinese astronomical satellite, successfully launched on Dec. 17 2015. As the most important payload of DAMPE, the BGO calorimeter contains 308 bismuth germanate crystals, with 616 photomultiplier tubes, one coupled to each end of every crystal. Environmental tests have been carried out to explore the environmental adaptability of the flight model of the BGO calorimeter. In this work we report the results of the vibration tests. During the vibration tests, no visible damage occurred in the mechanical assembly. After random or sinusoidal vibrations, the change of the first order natural frequency of BGO calorimeter during the modal surveys is less than 5%. The shift ratio of Most Probable Value of MIPs changes in cosmic-ray tests are shown, the mean value of which is about -4%. The comparison of results of cosmic-ray tests before and after the vibration shows no significant change in the performance of the BGO calorimeter. All these results suggest that the calorimeter and its structure have passed through the environment tests successfully. Supported by National Natural Science Foundation of China (11203090, 11003051, 11273070) and Strategic Priority Research Program on Space Science of Chinese Academy of Sciences (XDA04040202)

  1. FoCal - A high granularity electromagnetic calorimeter for forward direct photon measurements

    NASA Astrophysics Data System (ADS)

    Zhang, C.

    2017-02-01

    The measurement of direct photon production at forward rapidity (y ∼ 3 - 5) at the LHC provides access to the structure of protons and nuclei at very small values of fractional momentum (x ∼10-5) . FoCal, an extremely-high-granularity Forward Calorimeter covering 3.3 < η < 5.3 is proposed as a detector upgrade to the ALICE experiment. To facilitate the design of the upgrade and to perform generic R&D necessary for such a novel calorimeter, a compact high-granularity electromagnetic calorimeter prototype has been built. The corresponding R&D studies are the focus of this paper. The prototype is a Si/W sampling calorimeter. It was instrumented with 24 layers of Monolithic Active Pixel Sensors, a total of 39 M pixels. We report on performance studies of the prototype with test beams at DESY and CERN in a broad energy range. The results of the measurements demonstrate a very small Molière radius (∼ 11 mm) and good linearity of the response. Unique results on the detailed lateral shower shape, which are crucial for the two-shower separation capabilities, are presented. We compare the measurements to GEANT-based MC simulations, which additionally include a modeling of charge diffusion. The studies demonstrate the feasibility of this high-granularity technology for use in the proposed detector upgrade. They also show the extremely high potential of this technology for future calorimeter development.

  2. Design and Performance Tests of Ultra-Compact Calorimeters for High Energy Astrophysics

    NASA Technical Reports Server (NTRS)

    Salgado, Carlos W.

    2003-01-01

    This R&D project had two goals: a) the study of general-application ultra-compact calorimetry technologies for use in High Energy Astrophysics and, b) contribute to the design of an efficient calorimeter for the ACCESS mission. The direct measurement of galactic cosmic ray fluxes is performed from space or from balloon-borne detectors. Detectors used in those studies are limited in size and, specially, in weight. Since galactic cosmic ray fluxes are very small, detectors with high geometrical acceptances and long exposures are usually required for collecting enough statistics. We have studied calorimeter techniques that could produce large geometrical acceptance per unit of mass (G/w) and that may be used to study galactic cosmic rays at intermediate energies (knee energies).-The most important asset for detection of primary cosmic rays at and about the knee is large acceptance. To construct a large acceptance calorimeter (this term is used here in its most general accepted meaning of calorimeter as a device to measure particle energies ) the detector needs to be verv liaht or verv shallow . We studied two possible technologies to built compact calorimeters: the use of lead-tungstate crystals (PWO) and the use of sampling calorimetry using scintillating fibers embedded in a matrix of powder tungsten. For a very light detector, we considered the possibility of using Optical Transition Radiation (OTR) to measure the energy (and perhaps also direction and identity) of VHE cosmic rays.

  3. Design and performance of a vacuum-bottle solid-state calorimeter

    SciTech Connect

    Bracken, D.S.; Biddle, R.; Cech, R.

    1997-11-01

    EG and G Mound Applied Technologies calorimetry personnel have developed a small, thermos-bottle solid-state calorimeter, which is now undergoing performance testing at Los Alamos National Laboratory. The thermos-bottle solid-state calorimeter is an evaluation prototype for characterizing the heat output of small heat standards and other homogeneous heat sources. The current maximum sample size is 3.5 in. long with a diameter of 0.8 in. The overall size of the thermos bottle and thermoelectric cooling device is 9.25 in. high by 3.75 in. diameter and less than 3 lb. Coupling this unit with compact electronics and a laptop computer makes this calorimeter easily hand carried by a single individual. This compactness was achieved by servo controlling the reference temperature below room temperature and replacing the water bath used in conventional calorimeter design with the thermos-bottle insulator. Other design features will also be discussed. The performance of the calorimeter will be presented.

  4. Nuclear waste calorimeter for very large drums with 385 litres sample volume

    SciTech Connect

    Jossens, G.; Mathonat, C.; Bachelet, F.

    2015-03-15

    Calorimetry is a very precise and well adapted tool for the classification of drums containing nuclear waste material depending on their level of activities (low, medium, high). A new calorimeter has been developed by SETARAM Instrumentation and the CEA Valduc in France. This new calorimeter is designed for drums having a volume bigger than 100 liters. It guarantees high operator safety by optimizing drum handling and air circulation for cooling, and optimized software for direct measurement of the quantity of nuclear material. The LVC1380 calorimeter makes it possible to work over the range 10 to 3000 mW, which corresponds to approximately 0.03 to 10 g of tritium or 3 to 955 g of {sup 241}Pu in a volume up to 385 liters. This calorimeter is based on the heat flow measurement using Peltier elements which surround the drum in the 3 dimensions and therefore measure all the heat coming from the radioactive stuff whatever its position inside the drum. Calorimeter's insulating layers constitute a thermal barrier designed to filter disturbances until they represent less than 0.001 Celsius degrees and to eliminate long term disturbances associated, for example, with laboratory temperature variations between day and night. A calibration device based on Joule effect has also been designed. Measurement time has been optimized but remains long compared with other methods of measurement such as gamma spectrometry but its main asset is to have a good accuracy for low level activities.

  5. The lead-glass electromagnetic calorimeters for the magnetic spectrometers in Hall C at Jefferson Lab

    SciTech Connect

    Mkrtchyan, Hamlet; Carlini, Roger D.; Tadevosyan, Vardan H.; Arrington, John Robert; Asaturyan, Arshak Razmik; Christy, Michael Eric; Dutta, Dipangkar; Ent, Rolf; Fenker, Howard C.; Gaskell, David J.; Horn, Tanja; Jones, Mark K.; Keppel, Cynthia; Mack, David J.; Malace, Simona P.; Mkrtchyan, Arthur; Niculescu, Maria-Ioana; Seely, Charles Jason; Tvaskis, Vladas; Wood, Stephen A.; Zhamkochyan, Simon

    2013-08-01

    The electromagnetic calorimeters of the various magnetic spectrometers in Hall C at Jefferson Lab are presented. For the existing HMS and SOS spectrometers design considerations, relevant construction information, and comparisons of simulated and experimental results are included. The energy resolution of the HMS and SOS calorimeters is better than $\\sigma/E \\sim 6%/\\sqrt E $, and pion/electron ($\\pi/e$) separation of about 100:1 has been achieved in energy range 1 -- 5 GeV. Good agreement has been observed between the experimental and simulated energy resolutions, but simulations systematically exceed experimentally determined $\\pi^-$ suppression factors by close to a factor of two. For the SHMS spectrometer presently under construction details on the design and accompanying GEANT4 simulation efforts are given. The anticipated performance of the new calorimeter is predicted over the full momentum range of the SHMS. Good electron/hadron separation is anticipated by combining the energy deposited in an initial (preshower) calorimeter layer with the total energy deposited in the calorimeter.

  6. Influence of Catalysis and Oxidation on Slug Calorimeter Measurements in Arc Jets

    NASA Technical Reports Server (NTRS)

    Nawaz, Anuscheh; Driver, Dave; TerrazasSalinas, Imelda

    2012-01-01

    Arc jet tests play a critical role in the characterization and certification of thermal protection materials and systems (TPS). The results from these arc jet tests feed directly into computational models of material response and aerothermodynamics to predict the performance of the TPS in flight. Thus the precise knowledge of the plasma environment to which the test material is subjected, is invaluable. As one of the environmental parameters, the heat flux is commonly measured. The measured heat flux is used to determine the plasma enthalpy through analytical or computational models. At NASA Ames Research Center (ARC), slug calorimeters of a geometrically similar body to the test article are routinely used to determine the heat flux. A slug calorimeter is a thermal capacitance-type calorimeter that uses the temperature rise in a thermally insulated slug to determine the heat transfer rate, see Figure 1(left). Current best practices for measuring the heat flux with a slug calorimeter are described in ASTM E457 - 96. Both the calorimeter body and slug are made of Oxygen Free High Conductivity Copper, and are cleaned before each run.

  7. D-0 North End Cap Calorimeter Cold Test Results

    SciTech Connect

    Michael, J.; /Fermilab

    1990-08-02

    The North endcap calorimeter vessel was recieved on July 1, 1990. A cooldown of the pressure vessel with liquid nitrogen was performed on July 10-11 to check the vessel's integrity. With the pressure vessel cold, the insulating vacuum was monitored for leaks. Through out the testing, the insulating vacuum remained good and the vessel passed the test. The cold test was carried out per the procedures of D-Zero engineering note 3740.220-EN-250. The test was very similar to the cold test performed on the Central Calorimeter in October of 1987. Reference D-Zero engineering notes 3740.210-EN-122, 3740.000-EN107, and 3740.210-EN-110 for information about the CC cold test. The insulating vacuum space was pumped on while equipment was being connected to the pressure vessel. Two hours after starting to pump with the blower the vacuum space pressure was at about 210 microns. Pumping on the vacuum space for the next 15 hours showed no progress and a leak detector was connected to the pumping line. A leak check showed a leak in a thermocouple feedthru on the vacuum space relief plate. After fixing the leak, the pressure dropped to 16 microns in less than one hour. A rate of rise test was performed starting at a pressure of 13 microns. The pressure rose to 39 microns within 8 minutes and then only rose to 43 microns in 2.5 hours (1.6 microns/hour). After all connections were made to the pressure vessel, a vacuum pump with an estimated effective pumping speed of about 70 scfm was valved on. The lowest pressure achieved after 2 days of pumping was 80 microns. Valving out the pump for 30 minutes resulted in a 5 micron per minute rate of rise. The rate of rise was considered acceptable since there were known leak paths through the bolts of the signal ports. The EC North vessel was rolled outside of Lab A in preparation for a 5000 gallon liquid nitrogen trailer which arrived July, 10 at 8:00am. Before filling the vessel, the vacuum space pump was valved off. The pressure in the

  8. Development of a graphite probe calorimeter for absolute clinical dosimetry

    SciTech Connect

    Renaud, James; Seuntjens, Jan; Sarfehnia, Arman; Marchington, David

    2013-02-15

    The aim of this work is to present the numerical design optimization, construction, and experimental proof of concept of a graphite probe calorimeter (GPC) conceived for dose measurement in the clinical environment (U.S. provisional patent 61/652,540). A finite element method (FEM) based numerical heat transfer study was conducted using a commercial software package to explore the feasibility of the GPC and to optimize the shape, dimensions, and materials used in its design. A functioning prototype was constructed inhouse and used to perform dose to water measurements under a 6 MV photon beam at 400 and 1000 MU/min, in a thermally insulated water phantom. Heat loss correction factors were determined using FEM analysis while the radiation field perturbation and the graphite to water absorbed dose conversion factors were calculated using Monte Carlo simulations. The difference in the average measured dose to water for the 400 and 1000 MU/min runs using the TG-51 protocol and the GPC was 0.2% and 1.2%, respectively. Heat loss correction factors ranged from 1.001 to 1.002, while the product of the perturbation and dose conversion factors was calculated to be 1.130. The combined relative uncertainty was estimated to be 1.4%, with the largest contributors being the specific heat capacity of the graphite (type B, 0.8%) and the reproducibility, defined as the standard deviation of the mean measured dose (type A, 0.6%). By establishing the feasibility of using the GPC as a practical clinical absolute photon dosimeter, this work lays the foundation for further device enhancements, including the development of an isothermal mode of operation and an overall miniaturization, making it potentially suitable for use in small and composite radiation fields. It is anticipated that, through the incorporation of isothermal stabilization provided by temperature controllers, a subpercent overall uncertainty will be achieved.

  9. Studies on subcritical and overcritical density laser ablated TAC foam targets

    NASA Astrophysics Data System (ADS)

    Chaurasia, S.; Leshma, P.; Murali, C. G.; Borisenko, N. G.; Munda, D. S.; Orekhov, A.; Gromov, A. I.; Merkuliev, Yu. A.; Dhareshwar, L. J.

    2015-05-01

    In this paper, the interaction of high power laser with low density polymer foam with density as low as 2 mg/cm3, 4 mg/cm3, 20 mg/cm3 30 mg/cm3 and 50 mg/cm3 targets are investigated and compared with solid polymer targets. An understanding of such interaction is important from fusion research point of view. Low density foam coating of fusion capsule has been proposed in order to smooth in direct drive scheme and also it is being used as efficient x-ray converter in indirect drive scheme. It is observed that about 75-80% of the laser energy is absorbed in the subcritical (with density <4 mg/cm3) foam targets and the soft x-ray yield in this case is almost two times that measured in the over dense (supper critical) targets. The optical shadowgraphy of the targets shows that the laser coupling in low density foam is associated with a supersonic heat wave while, with increasing density this phenomenon is replaced by subsonic absorption and shock formation. In the case of a 50 mg/cm3 foams the foil velocity reduced by 35% (i.e. 5×106 cm/s), which further reduced to 3.8×106 cm/s in case solid polymer targets.

  10. New electronics of the spectrometric channel for the SND detector electromagnetic calorimeter

    NASA Astrophysics Data System (ADS)

    Achasov, M. N.; Aulchenko, V. M.; Bogdanchikov, A. G.; Druzhinin, V. P.; Golubev, V. B.; Korol, A. A.; Koshuba, S. V.; Kovrizhin, D. P.; Serednyakov, S. I.; Surin, I. K.; Tekut`ev, A. I.; Usov, Yu. V.

    2016-07-01

    The Spherical Neutral Detector (SND) is intended for study of electron-positron annihilation at the VEPP-2000 e+e- collider (BINP, Novosibirsk) in the center-of-mass energy region below 2 GeV. The main part of the detector is a three-layer electromagnetic calorimeter based on NaI(Tl) crystals. The physics program of the SND experiment includes a high statistics study of neutron-antineutron production near threshold, for which time measurements in the calorimeter are required. In this paper we describe new shaping and digitizing calorimeter electronics, which allow to reach a time resolution of about 1 ns for 100 MeV signal and an amplitude resolution of about 250 keV.

  11. High energy γ-ray detection with the AMS-02 electromagnetic calorimeter

    NASA Astrophysics Data System (ADS)

    Bigongiari, G.; Cervelli, F.; Coignet, G.; Goy, C.; Di Falco, S.; Guerri, I.; Incagli, M.; Morescalchi, L.; Pilo, F.; Rosier-Lees, S.; Vialle, J. P.; Vitillo, S.

    2017-04-01

    The electromagnetic Calorimeter (ECAL) of the AMS-02 experiment is a fine grained lead-scintillating fibers sampling calorimeter that allows for a precise 3-dimensional imaging of the longitudinal and lateral developement of electromagnetic showers. With a total thickness of 17X0 , electromagnetic showers are well contained and the energy resolution is 2% up to 1 TeV. ECAL provides a high discrimination between electromagnetic and hadronic showers; furthermore, together with the rest of the AMS-02 detector, it is able to identify the subdominant (≃10-6) photon flux from GeV up to TeV energies. Thanks to its high granularity ECAL has an excellent pointing capability (0 .5o at high energies) that offers an unusual possibility of drawing sky maps with the calorimeter standalone.

  12. Heat loss through connecting thermistor wires in a three-body graphite calorimeter

    NASA Astrophysics Data System (ADS)

    Radu, D.; Guerra, A. S.; Ionita, C.; Astefanoaei, I.

    2010-06-01

    The main aim of this paper is to calculate the small but significant amount of heat lost from a graphite calorimeter absorber through connecting thermistor wires during electrical calibration. Taking into account the electro-thermal interaction between the heating thermistor and its surrounding environment, a more realistic approach to the problem was developed and estimative numerical results were obtained. It was found that the wires contribute about 0.01% in extracting heat from the calorimeter core (which corresponds to a correction factor kwcore = 0.9999). The total correction factor for heat loss through the connecting thermistor wires during the electrical calibration of the calorimeter (the total combined effect of the heater and the sensor leads due to conduction, radiation and Joule effect) was determined: kw = 0.9989.

  13. Energy reconstruction in a highly granularity semi-digital hadronic calorimeter

    SciTech Connect

    Sameh Mannai

    2015-07-01

    A semi-digital hadronic calorimeter using Glass Resistive Plate Chambers (GRPCs) is one of the calorimeters candidates proposed for particle physics experiments at the future electrons collider. It is a high granular calorimeter which is required for application of the particle flow algorithm in order to improve the jet energy resolution as one of the goals of this experiments. We discussed the energy reconstruction, based on digital and semi-Digital methods, to study the effect on the improvement of the single particle energy resolution and the linearity of the detector response. This study was performed with the GEANT4 simulation. Results on the energy resolution and linearity, for negative pions over an energy range from 1 to 100 GeV are presented and compared with different energy reconstruction methods including Artificial Neural Networks. (authors)

  14. The large volume radiometric calorimeter system: A transportable device to measure scrap category plutonium

    SciTech Connect

    Duff, M.F.; Wetzel, J.R.; Breakall, K.L.; Lemming, J.F.

    1987-01-01

    An innovative design concept has been used to design a large volume calorimeter system. The new design permits two measuring cells to fit in a compact, nonevaporative environmental bath. The system is mounted on a cart for transportability. Samples in the power range of 0.50 to 12.0 W can be measured. The calorimeters will receive samples as large as 22.0 cm in diameter by 43.2 cm high, and smaller samples can be measured without lengthening measurement time or increasing measurement error by using specially designed sleeve adapters. This paper describes the design considerations, construction, theory, applications, and performance of the large volume calorimeter system. 2 refs., 5 figs., 1 tab.

  15. The time structure of hadronic showers in highly granular calorimeters with tungsten and steel absorbers

    NASA Astrophysics Data System (ADS)

    Adloff, C.; Blaising, J.-J.; Chefdeville, M.; Drancourt, C.; Gaglione, R.; Geffroy, N.; Karyotakis, Y.; Koletsou, I.; Prast, J.; Vouters, G.; Repond, J.; Schlereth, J.; Xia, L.; Baldolemar, E.; Li, J.; Park, S. T.; Sosebee, M.; White, A. P.; Yu, J.; Eigen, G.; Thomson, M. A.; Ward, D. R.; Benchekroun, D.; Hoummada, A.; Khoulaki, Y.; Apostolakis, J.; Arfaoui, S.; Benoit, M.; Dannheim, D.; Elsener, K.; Folger, G.; Grefe, C.; Ivantchenko, V.; Killenberg, M.; Klempt, W.; van der Kraaij, E.; Linssen, L.; Lucaci-Timoce, A.-I.; Münnich, A.; Poss, S.; Ribon, A.; Roloff, P.; Sailer, A.; Schlatter, D.; Sicking, E.; Strube, J.; Uzhinskiy, V.; Cârloganu, C.; Gay, P.; Manen, S.; Royer, L.; Cornett, U.; David, D.; Ebrahimi, A.; Falley, G.; Feege, N.; Gadow, K.; Göttlicher, P.; Günter, C.; Hartbrich, O.; Hermberg, B.; Karstensen, S.; Krivan, F.; Krüger, K.; Lu, S.; Lutz, B.; Morozov, S.; Morgunov, V.; Neubüser, C.; Reinecke, M.; Sefkow, F.; Smirnov, P.; Terwort, M.; Fagot, A.; Tytgat, M.; Zaganidis, N.; Hostachy, J.-Y.; Morin, L.; Garutti, E.; Laurien, S.; Marchesini, I.; Matysek, M.; Ramilli, M.; Briggl, K.; Eckert, P.; Harion, T.; Schultz-Coulon, H.-Ch; Shen, W.; Stamen, R.; Chang, S.; Khan, A.; Kim, D. H.; Kong, D. J.; Oh, Y. D.; Bilki, B.; Norbeck, E.; Northacker, D.; Onel, Y.; Wilson, G. W.; Kawagoe, K.; Miyazaki, Y.; Sudo, Y.; Ueno, H.; Yoshioka, T.; Dauncey, P. D.; Cortina Gil, E.; Mannai, S.; Baulieu, G.; Calabria, P.; Caponetto, L.; Combaret, C.; Della Negra, R.; Eté, R.; Grenier, G.; Han, R.; Ianigro, J.-C.; Kieffer, R.; Laktineh, I.; Lumb, N.; Mathez, H.; Mirabito, L.; Petrukhin, A.; Steen, A.; Tromeur, W.; Vander Donckt, M.; Zoccarato, Y.; Berenguer Antequera, J.; Calvo Alamillo, E.; Fouz, M.-C.; Puerta-Pelayo, J.; Corriveau, F.; Bobchenko, B.; Chadeeva, M.; Danilov, M.; Epifantsev, A.; Markin, O.; Mizuk, R.; Novikov, E.; Rusinov, V.; Tarkovsky, E.; Kozlov, V.; Soloviev, Y.; Besson, D.; Buzhan, P.; Ilyin, A.; Kantserov, V.; Kaplin, V.; Popova, E.; Tikhomirov, V.; Gabriel, M.; Kiesling, C.; Seidel, K.; Simon, F.; Soldner, C.; Szalay, M.; Tesar, M.; Weuste, L.; Amjad, M. S.; Bonis, J.; Conforti di Lorenzo, S.; Cornebise, P.; Fleury, J.; Frisson, T.; van der Kolk, N.; Richard, F.; Pöschl, R.; Rouëné, J.; Anduze, M.; Balagura, V.; Becheva, E.; Boudry, V.; Brient, J.-C.; Cornat, R.; Frotin, M.; Gastaldi, F.; Guliyev, E.; Haddad, Y.; Magniette, F.; Ruan, M.; Tran, T. H.; Videau, H.; Callier, S.; Dulucq, F.; Martin-Chassard, G.; de la Taille, Ch; Raux, L.; Seguin-Moreau, N.; Zacek, J.; Cvach, J.; Gallus, P.; Havranek, M.; Janata, M.; Kvasnicka, J.; Lednicky, D.; Marcisovsky, M.; Polak, I.; Popule, J.; Tomasek, L.; Tomasek, M.; Ruzicka, P.; Sicho, P.; Smolik, J.; Vrba, V.; Zalesak, J.; Belhorma, B.; Ghazlane, H.; Kotera, K.; Ono, H.; Takeshita, T.; Uozumi, S.; Chai, J. S.; Song, H. S.; Lee, S. H.; Götze, M.; Sauer, J.; Weber, S.; Zeitnitz, C.

    2014-07-01

    The intrinsic time structure of hadronic showers influences the timing capability and the required integration time of hadronic calorimeters in particle physics experiments, and depends on the active medium and on the absorber of the calorimeter. With the CALICE T3B experiment, a setup of 15 small plastic scintillator tiles read out with Silicon Photomultipliers, the time structure of showers is measured on a statistical basis with high spatial and temporal resolution in sampling calorimeters with tungsten and steel absorbers. The results are compared to GEANT4 (version 9.4 patch 03) simulations with different hadronic physics models. These comparisons demonstrate the importance of using high precision treatment of low-energy neutrons for tungsten absorbers, while an overall good agreement between data and simulations for all considered models is observed for steel.

  16. The large volume calorimeter for measuring the pressure cooker'' shipping container

    SciTech Connect

    Kasperski, P.W.; Duff, M.F.; Wetzel, J.R. ); Baker, L.B.; MacMurdo, K.W. )

    1991-01-01

    A precise, low wattage, large volume calorimeter system has been developed at Mound to measure two configurations of the 12081 containment vessel. This system was developed and constructed to perform verification measurements at the Savannah River Site. The calorimeter system has performance design specifications of {plus minus}0.3% error above the 2-watt level, and {plus minus}(0.03% plus 0.006 watts) at power levels below 2 watts (one sigma). Data collected during performance testing shows measurement errors well within this range, even down to 0.1-watt power levels. The development of this calorimeter shows that ultra-precise measurements can be achieved on extremely large volume sample configurations. 1 ref., 5 figs.

  17. Design, status and test of the Mu2e crystal calorimeter

    SciTech Connect

    Martini, Matteo; et al.

    2016-06-17

    The Mu2e experiment at Fermilab searches for the charged-lepton flavor violating neutrino-less conversion of a negative muon into an electron in the field of a aluminum nucleus. The dynamic of such a process is well modeled by a two-body decay, resulting in a monoenergetic electron with an energy slightly below the muon rest mass (104.967 MeV). The calorimeter of this experiment plays an important role to provide excellent particle identification capabilities and an online trigger filter while aiding the track reconstruction capabilities. The baseline calorimeter configuration consists of two disks each made with about 700 undoped CsI crystals read out by two large area UV-extended Silicon Photomultipliers. These crystals match the requirements for stability of response, high resolution and radiation hardness. In this paper we present the final calorimeter design.

  18. Classification of high-energy antiprotons on electrons background based on calorimeter data in PAMELA experiment

    NASA Astrophysics Data System (ADS)

    Dunaeva, O. A.; Alekseev, V. V.; Bogomolov, Yu V.; Lukyanov, A. D.; Malakhov, V. V.; Mayorov, A. G.; Rodenko, S. A.

    2017-01-01

    In modern experimental physics a heterogeneous coordinate-sensitive calorimeters are widely used due to their good characteristics and possibilities to obtain a three-dimensional information of particles interactions. Especially it is important at high-energies when electromagnetic or hadron showers are arise. We propose a quit efficient method to identify antiprotons (positrons) with energies more than 10 GeV on electron (proton) background by calorimeter of such kind. We construct the AdaBoost classifier and SVM to separate particles into two classes, different combinations of energy release along reconstructed particle trajectory were used as feature vector. We test a preliminary version of the method on a calorimeter of the PAMELA magnetic spectrometer. For high-energy particles we got a good quality of classification: it lost about 5 · 10‑2 of antiprotons, and less than 4 · 10‑4 of electrons were classified to antiproton class.

  19. The use of thermistors in the NPL electron-beam calorimeter

    NASA Astrophysics Data System (ADS)

    McEwen, M. R.; Burns, D. T.; Williams, A. J.

    1993-03-01

    The system developed for calibrating thermistors, which have been employed in the primary standard electron beam graphite calorimeter for several years, and the results of investigations into self-heating and dose response are described. The overall uncertainty in measuring temperature rises is estimated to be +/- 0.1 percent at the 95 percent confidence level. The self-heating of the thermistor type used in the calorimeter was determined to be constant over the temperature range 14 to 29 C. The same thermistor type showed no change in response within the uncertainties to an accumulated dose up to 3000 kGy. A second type of thermistor (to be used in a new calorimeter) showed no change in sensitivity although there was a change in absolute resistance of approximately 0.1 percent per MGy.

  20. RLCYC 75 : a 2 kW electrically calibrated laser calorimeter designed for Laser MegaJoule diagnostics calibration

    NASA Astrophysics Data System (ADS)

    Crespy, C.; Villate, D.; Soscia, M.; Coste, F.; Andre, R.

    2013-02-01

    RLCYC 75 is a new electrically calibrated laser calorimeter specially manufactured by Laser Metrology to calibrate energy diagnostics within the Laser MegaJoule (LMJ) facility. It consists of an optical cavity cooled by a hydraulic system. The system is designed to provide 1 µm wavelength power laser measurements with uncertainty less than 1% at 2 kW and traceability to the International System of Units (SI). In this paper, the accuracy of RLCYC 75 measurements is studied. More precisely, three points are detailed: instrumentation uncertainty estimation, equivalence between optical and electrical supply and light absorption. To this end, electrical calibration campaigns and power laser measurement campaigns are conducted. Moreover, thermal and optical models are developed. Results show that RLCYC 75 design and instrumentation are efficient enough to reach the goal of relative uncertainty of about 1% at 2 kW. RLCYC 75 will become the 2 kW laser power primary standard for LMJ applications.

  1. Compressor calorimeter performance of refrigerant blends: Comparative methods and results for a refrigerator/freezer application

    SciTech Connect

    Rice, C K; Sand, J R

    1993-01-01

    A protocol was developed to define calorimeter operating pressures for nonazeotropic refrigerant mixtures (NARMs) which corresponded with the saturated evaporator and condenser temperatures commonly used for pure refrigerants. Compressor calorimeter results were obtained using this equivalent-mean-temperature (EMT) approach and a generally applied Association of Home Appliance Manufacturers (AHAM) procedure at conditions characteristic of a domestic refrigerator-freezer application. Tests with R-12 and two NARMs indicate that compressor volumetric and isentropic efficiencies are nearly the same for refrigerants with similar capacities and pressure ratios. The liquid-line temperature conditions specified in the AHAM calorimeter rating procedure for refrigerator-freezer compressors were found to preferentially derate NARM performance relative to R-12. Conversion of calorimeter data taken with a fixed liquid-line temperature to a uniform minimal level of condenser subcooling is recommended as a fairer procedure when NARMs are involved. Compressor energy-efficiency-ratio (EER) and capacity data measured as a result of the EMT approach were compared to system performance calculated using an equivalent-heat-exchanger-loading (EHXL) protocol based on a Lorenz-Meutzner (L-M) refrigerator-freezer modeling program. The EHXL protocol was used to transform the calorimeter results into a more relevant representation of potential L-M cycle performance. The EMT method used to set up the calorimeter tests and the AHAM liquid-line conditions combined to significantly understate the cycle potential of NARMs relative to that predicted at the more appropriate EHXL conditions. Compressor conditions representative of larger heat exchanger sizes were also found to give a smaller L-M cycle advantage relative to R-12.

  2. Compressor calorimeter performance of refrigerant blends: Comparative methods and results for a refrigerator/freezer application

    NASA Astrophysics Data System (ADS)

    Rice, C. K.; Sand, J. R.

    1993-01-01

    A protocol was developed to define calorimeter operating pressures for nonazeotropic refrigerant mixtures (NARM's) which corresponded with the saturated evaporator and condenser temperatures commonly used for pure refrigerants. Compressor calorimeter results were obtained using this equivalent-mean-temperature (EMT) approach and a generally applied Association of Home Appliance Manufacturers (AHAM) procedure at conditions characteristic of a domestic refrigerator-freezer application. Tests with R-12 and two NARM's indicate that compressor volumetric and isentropic efficiencies are nearly the same for refrigerants with similar capacities and pressure ratios. The liquid-line temperature conditions specified in the AHAM calorimeter rating procedure for refrigerator-freezer compressors were found to preferentially derate NARM performance relative to R-12. Conversion of calorimeter data taken with a fixed liquid-line temperature to a uniform minimal level of condenser subcooling is recommended as a fairer procedure when NARM's are involved. Compressor energy-efficiency-ratio (EER) and capacity data measured as a result of the EMT approach were compared to system performance calculated using an equivalent heat exchanger loading (EHXL) protocol based on a Lorenz-Meutzner (L-M) refrigerator-freezer modeling program. The EHXL protocol was used to transform the calorimeter results into a more relevant representation of potential L-M cycle performance. The EMT method used to set up the calorimeter tests and the AHAM liquid-line conditions combined to significantly understate the cycle potential of NARM's relative to that predicted at the more appropriate EHXL conditions. Compressor conditions representative of larger heat exchanger sizes were also found to give a smaller L-M cycle advantage relative to R-12.

  3. Characterization of 1800 Hamamatsu R7600-M4 PMTs for CMS HF Calorimeter upgrade

    NASA Astrophysics Data System (ADS)

    Akgun, U.; Funk, G.; Corso, J.; Jia, Z.; Southwick, D.; Adams, L.; Kingyon, J.; Tiras, E.; Munhollon, T.; Troendle, E.; Bruecken, P.; Khristenko, V.; Onel, Y.

    2014-06-01

    The Hadronic Forward calorimeters of the CMS experiment are Cherenkov calorimeters that use quartz fibers and 1728 photomultiplier tubes (PMTs) for readout. The CMS detector upgrade project requires the current Hamamatsu R7525 PMTs to be replaced with 4-anode, high quantum efficiency R7600-M4 PMTs. The new PMTs will improve the detector resolution, as well as the capability of removing fake events due to signal created in the glass window of the PMT. Here, we report the dark current, anode gain, transit time, transit time spread, pulse width, rise time, and linearity measurements performed on 1800 Hamamatsu R7600-200-M4 PMTs.

  4. The upgrade of the PreProcessor system of the ATLAS level-1 calorimeter trigger

    NASA Astrophysics Data System (ADS)

    Andrei, V.; Hanke, P.; Jongmanns, J.; Khomich, A.; Meier, K.; Schmitt, K.; Schultz-Coulon, H.-C.; Stamen, R.; Stock, P.; Wessels, M.

    2012-12-01

    The ATLAS Level-1 Calorimeter Trigger is a pipelined system to identify high-pT objects and to build energy sums within a fixed latency of ~ 2 μs. It consists of a PreProcessor, which conditions and digitises analogue calorimeter signals, and two object-finding processors. The PreProcessor's tasks are implemented on a Multi-Chip Module, holding ADCs, time-adjustment and digital processing ASICs, and LVDS serialisers. A pin-compatible substitute, based on today's technology, like dual-channel ADCs and FPGAs, has been built to improve the BCID and pedestal subtraction algorithms. Test results with the first prototype are presented.

  5. The SOUDAN 2 detector The operation and performance of the tracking calorimeter modules

    NASA Astrophysics Data System (ADS)

    Allison, W. W. M.; Alner, G. J.; Ambats, I.; Ayres, D. S.; Balka, L. J.; Barr, G. D.; Barrett, W. L.; Benjamin, D.; Bode, C.; Border, P. M.; Brooks, C. B.; Cobb, J. H.; Cockerill, D. J. A.; Coover, K.; Cotton, R. J.; Courant, H.; Dahlin, B. B.; DasGupta, U.; Dawson, J. W.; Demuth, D. M.; Edwards, V. W.; Ewen, B.; Fields, T. H.; Garcia-Garcia, C.; Gallagher, H. M.; Giles, R. H.; Giller, G. L.; Goodman, M. C.; Gray, R. N.; Heppelmann, S.; Hill, N.; Hoftiezer, J. H.; Jankowski, D. J.; Johns, K.; Joyce, T.; Kafka, T.; Kasahara, S. M. S.; Kirby-Gallagher, L. M.; Kochocki, J.; Leeson, W.; Litchfield, P. J.; Longley, N. P.; Lopez, F. V.; Lowe, M. J.; Mann, W. A.; Marshak, M. L.; May, E. N.; Maxam, D.; McMaster, L.; Milburn, R.; Miller, W. H.; Minor, C. P.; Mondal, N.; Mualem, L.; Napier, A.; Nelson, E. M.; Nickson, R.; Oliver, W.; Pearce, G. F.; Perkins, D. H.; Peterson, E. A.; Price, L. E.; Roback, D. M.; Rosen, D. B.; Ruddick, K.; Saitta, B.; Schmid, D. J.; Schlereth, J.; Schneps, J.; Schub, M. H.; Seidlein, R. V.; Shield, P. D.; Shupe, M. A.; Spear, S.; Stassinakis, A.; Sundaralingam, N.; Thomson, M. A.; Thron, J. L.; Vassiliev, V.; Villaume, G.; Wakely, S. P.; Wall, D.; Wallis, E. W. G.; Weems, L.; Werkema, S. J.; West, N.; Wielgosz, U.; Woods, C. A.; Yarker, S.

    1996-02-01

    SOUDAN 2 is a 960-ton tracking calorimeter which has been constructed to search for nucleon decay and other phenomena. The full detector consists of 224 calorimeter modules each weighing 4.3 tons. The modules consist of finely segmented iron instrumented with 1 m long drift tubes of 15 mm internal diameter. The tubes enable three spatial coordinates and {dE }/{dx } to be recorded for charged particles traversing the tubes. The spatial resolution is 0.38 cm in the x- y plane and 0.65 cm in the z, or drift, direction. The operation and performance of the modules are discussed.

  6. Development of ATLAS Liquid Argon Calorimeter front-end electronics for the HL-LHC

    NASA Astrophysics Data System (ADS)

    Liu, T.

    2017-01-01

    The high-luminosity phase of the Large Hadron Collider will provide 5–7 times greater luminosities than assumed in the original detector design. An improved trigger system requires an upgrade of the readout electronics of the ATLAS Liquid Argon Calorimeter. Concepts for the future readout of the 182,500 calorimeter cells at 40–80 MHz and 16-bit dynamic range and the developments of radiation-tolerant, low-noise, low-power, and high-bandwidth front-end electronic components, including preamplifiers and shapers, 14-bit ADCs, and 10-Gb/s laser diode array drivers, are presented in this paper.

  7. HARDROC3, a 3rd generation ASIC with zero suppress for ILC Semi Digital Hadronic Calorimeter

    NASA Astrophysics Data System (ADS)

    Dulucq, F.; Callier, S.; de La Taille, C.; Martin-Chassard, G.; Seguin-Moreau, N.; Zoccarato, Y.

    2017-02-01

    HARDROC is the front end chip designed to read out the Resistive Plate Chambers foreseen for the Digital HAdronic CALorimeter (DHCAL) of the future International Linear Collider. The very fine granularity of the calorimeter implies thousands of electronics channels per cubic meter which is a new feature of "imaging" calorimetry. Moreover, for compactness, chips must be embedded inside the detector making crucial the reduction of the power consumption down to 12 μ W per channel. This is achieved using power-pulsing and online zero-suppression. Around 800 HARDROC3 were produced in 2015. The overall performance and production tests will be detailed.

  8. Test beam results from the D0 liquid argon end calorimeter electromagnetic module

    SciTech Connect

    Spadafora, A.L.

    1991-08-01

    Results are presented from a test beam study of the D0 liquid argon end calorimeter electromagnetic module prior to its installation at the Fermilab Tevatron Collider. Using electron beams with energies ranging from 10--150 GeV we have obtained an energy resolution of 15.7%/{radical}E(GeV) with a small constant term of 0.3% and a linearity of better than {plus minus}0.5%. The position resolution of the calorimeter is found to approximately 1 mm for 100 GeV electrons. 7 refs., 8 figs., 3 tabs.

  9. The Calorimeter Trigger Processor Card: the next generation of high speed algorithmic data processing at CMS

    NASA Astrophysics Data System (ADS)

    Svetek, A.; Blake, M.; Cepeda Hermida, M.; Dasu, S.; Dodd, L.; Fobes, R.; Gomber, B.; Gorski, T.; Guo, Z.; Klabbers, P.; Levine, A.; Ojalvo, I.; Ruggles, T.; Smith, N.; Smith, W. H.; Tikalsky, J.; Vicente, M.; Woods, N.

    2016-02-01

    The CMS Level-1 upgraded calorimeter trigger requires a powerful, flexible and compact processing card. The Calorimeter Trigger Processor Card (CTP7) uses the Virtex-7 FPGA as its primary data processor and is the first FPGA based processing card in CMS to employ the ZYNQ System-on-Chip (SoC) running embedded Linux to provide TCP/IP communication and board support functions. The CTP7 was built from the ground up to support AXI infrastructure to provide flexible and modular designs with minimal time from project conception to final implementation.

  10. Expected performance of the CDF plug upgrade calorimeter at TeV33

    SciTech Connect

    Hara, K.; Kim, S.; Takikawa, K.; CDF Collaboration

    1996-11-01

    We have evaluated the performance of the CDF plug tile/fiber calorimeter under the radiation environment at a luminosity of 1 x 10{sup 33}cm{sup -2}s{sup -1} at TeV33. The issues covered are the radiation damage, the anode current of photomultipliers, and the energy miss-measurement due to the minimum bias event pile-ups. The plug calorimeter is expected to perform as precision calorimetry in the pseudorapidity range up to {approximately}2.3.

  11. High precision, low disturbance calibration system for the CMS Barrel Electromagnetic Calorimeter High Voltage apparatus

    NASA Astrophysics Data System (ADS)

    Fasanella, G.

    2017-01-01

    The CMS Electromagnetic Calorimeter utilizes scintillation lead tungstate crystals, with avalanche photodiodes (APD) as photo-detectors in the barrel part. 1224 HV channels bias groups of 50 APD pairs, each at a voltage of about 380 V. The APD gain dependence on the voltage is 3%/V. A stability of better than 60 mV is needed to have negligible impact on the calorimeter energy resolution. Until 2015 manual calibrations were performed yearly. A new calibration system was deployed recently, which satisfies the requirement of low disturbance and high precision. The system is discussed in detail and first operational experience is presented.

  12. Measurement of liquid water content in a melting snowpack using cold calorimeter techniques

    NASA Technical Reports Server (NTRS)

    Rango, A.; Jones, E. B.; Howell, S.

    1980-01-01

    Liquid water in a snowpack is a quantifiable parameter of hydrological significance. It is also important in the interpretation of snowpack remote sensing data using microwave techniques. One acceptable approach to measuring liquid water content of a snowpack (by weight) is the cold calorimeter. This technique is presented from theory through application. Silicon oil was used successfully as the freezing agent. Consistent results can be obtained even when using operators with a minimum of training. Data can be obtained approximately every 15 minutes by using two calorimeters and three operators. Accuracy within one to two percent can be achieved under reasonable field conditions.

  13. Addition of photosensitive dopants to the D0 liquid argon calorimeter

    SciTech Connect

    Amos, N.A.; Anderson, D.F.

    1992-10-01

    The addition of photosensitive dopants to liquid argon greatly enhances the signal from heavily ionizing particles. Since binding energy losses we correlated with the heavily ionizing component in hadronic showers, the addition of photosensitive dopants has been suggested as a mechanism to tune the e/[pi] ratio in liquid argon calorimeters. A measurement was performed at the FNAL test beam, adding 4 ppM tetramethylgermanium to the D[phi] uranium-liquid argon calorimeter. An increase in response for electromagnetic and hadronic showers was observed, with no net change in the e/[pi] ratio.

  14. Addition of photosensitive dopants to the D0 liquid argon calorimeter

    SciTech Connect

    Amos, N.A.; Anderson, D.F.; The D0 Collaboration

    1992-10-01

    The addition of photosensitive dopants to liquid argon greatly enhances the signal from heavily ionizing particles. Since binding energy losses we correlated with the heavily ionizing component in hadronic showers, the addition of photosensitive dopants has been suggested as a mechanism to tune the e/{pi} ratio in liquid argon calorimeters. A measurement was performed at the FNAL test beam, adding 4 ppM tetramethylgermanium to the D{phi} uranium-liquid argon calorimeter. An increase in response for electromagnetic and hadronic showers was observed, with no net change in the e/{pi} ratio.

  15. CALORIC: A readout chip for high granularity calorimeter

    SciTech Connect

    Royer, L.; Bonnard, J.; Manen, S.; Gay, P.; Soumpholphakdy, X.

    2011-07-01

    A very-front-end electronics has been developed to fulfil requirements for the next generation of electromagnetic calorimeters. The compactness of this kind of detector and its large number of channels (up to several millions) impose a drastic limitation of the power consumption and a high level of integration. The electronic channel proposed is first of all composed of a low-noise Charge Sensitive Amplifier (CSA) able to amplify the charge delivered by a silicon diode up to 10 pC. Next, a two-gain shaping, based on a Gated Integration (G.I.), is implemented to cover the 15 bits dynamic range required: a high gain shaper processes signals from 4 fC (charge corresponding to the MIP) up to 1 pC, and a low gain filter handles charges up to 10 pC. The G.I. performs also the analog memorization of the signal until it is digitalized. Hence, the analog-to-digital conversion is carried out through a low-power 12-bit cyclic ADC. If the signal overloads the high-gain channel dynamic range, a comparator selects the low-gain channel instead. Moreover, an auto-trigger channel has been implemented in order to select and store a valid event over the noise. The timing sequence of the channel is managed by a digital IP. It controls the G.I. switches, generates all needed clocks, drives the ADC and delivers the final result over 12 bits. The whole readout channel is power controlled, which permits to reduce the consumption according to the duty cycle of the beam collider. Simulations have been performed with Spectre simulator on the prototype chip designed with the 0.35 {mu}m CMOS technology from Austriamicrosystems. Results show a non-linearity better than 0.1% for the high-gain channel, and a non-linearity limited to 1% for the low-gain channel. The Equivalent Noise Charge referred to the input of the channel is evaluated to 0.4 fC complying with the MIP/10 limit. With the timing sequence of the International Linear Collider, which presents a duty cycle of 1%, the power

  16. Studies of Excess Heat and Convection in a Water Calorimeter.

    PubMed

    Domen, J K; Domen, S R

    2001-01-01

    To explain a difference of 0.5 % between the absorbed-dose standards of the National Institute of Standards and Technology (NIST) and the National Research Council of Canada (NRCC), Seuntjens et al. suggest the fault lies with the NIST water calorimeter being operated at 22 °C and the method with which the measurements were made. Their calculations show that this difference is due to overprediction of temperature rises of six consecutive (60)Co radiation runs at NIST. However, the consecutive runs they refer to were merely preliminary measurements to determine the procedure for the NIST beam calibration. The beam calibration was determined from only two consecutive runs followed by water circulation to re-establish temperature equilibrium. This procedure was used for measurements on 77 days, with 32 runs per day. Convection external to the glass cylindrical detector assembly performed a beneficial role. It aided (along with conduction) in increasing the rate of excess heat transported away from the thin cylindrical wall. This decreased the rate of heat conducted toward the axially located thermistors. The other sources of excess heat are the: (1) non-water materials in the temperature probe, and (2) exothermic effect of the once-distilled water external to the cylinder. Finite-element calculations were made to determine the separate and combined effects of the excess heat sources for the afterdrift. From this analysis, extrapolation of the measured afterdrifts of two consecutive runs to mid radiation leads to an estimated over-prediction of no more than about 0.1 %. Experimental measurements contradict the calculated results of Seuntjens et al. that convective motion (a plume) originates from the thermistors operated with an electrical power dissipation as low as 0.6 μW, well below the measured threshold of 50 μW. The method used for detecting a plume was sensitive enough to measure a convective plume (if it had started) down to about the 10 μW power level

  17. Studies of Excess Heat and Convection in a Water Calorimeter

    PubMed Central

    Domen, John K.; Domen, Steve R.

    2001-01-01

    To explain a difference of 0.5 % between the absorbed-dose standards of the National Institute of Standards and Technology (NIST) and the National Research Council of Canada (NRCC), Seuntjens et al. suggest the fault lies with the NIST water calorimeter being operated at 22 °C and the method with which the measurements were made. Their calculations show that this difference is due to overprediction of temperature rises of six consecutive 60Co radiation runs at NIST. However, the consecutive runs they refer to were merely preliminary measurements to determine the procedure for the NIST beam calibration. The beam calibration was determined from only two consecutive runs followed by water circulation to re-establish temperature equilibrium. This procedure was used for measurements on 77 days, with 32 runs per day. Convection external to the glass cylindrical detector assembly performed a beneficial role. It aided (along with conduction) in increasing the rate of excess heat transported away from the thin cylindrical wall. This decreased the rate of heat conducted toward the axially located thermistors. The other sources of excess heat are the: (1) non-water materials in the temperature probe, and (2) exothermic effect of the once-distilled water external to the cylinder. Finite-element calculations were made to determine the separate and combined effects of the excess heat sources for the afterdrift. From this analysis, extrapolation of the measured afterdrifts of two consecutive runs to mid radiation leads to an estimated over-prediction of no more than about 0.1 %. Experimental measurements contradict the calculated results of Seuntjens et al. that convective motion (a plume) originates from the thermistors operated with an electrical power dissipation as low as 0.6 μW, well below the measured threshold of 50 μW. The method used for detecting a plume was sensitive enough to measure a convective plume (if it had started) down to about the 10 μW power level

  18. Effects of cage size and enrichment on reproductive performance and behavior in C57BL/6Tac mice.

    PubMed

    Whitaker, Julia; Moy, Sheryl S; Godfrey, Virginia; Nielsen, Judith; Bellinger, Dwight; Bradfield, John

    2009-01-01

    The authors examined the effects of cage size and enrichment on mouse breeding performance and behavior. Breeding trios of C57BL/6Tac mice were housed in cages of two different sizes ('standard' and 'large' cages with 82 in(2) and 124 in(2) floor space, respectively). Half of the cages of each size contained four enrichment items (Nestlet, plastic tunnel, nylon rings and running wheel), whereas the remaining cages had no enrichment. The authors measured the following reproductive parameters: litter size, number of pups that survived to weaning age, average pup weights at 21 d after birth and number of days between births of litters. A subset of weaned male and female pups from each cage size and enrichment condition completed a suite of behavioral tests. Pups raised in large cages weighed less than those raised in standard cages. Enrichment and cage size had certain behavioral effects, which were dependent on gender and behavioral measure. Male pups born in enriched cages showed more anxiety-like behavior and less exploration than did males born in non-enriched cages. Though being raised in enriched or large cages did not clearly improve pups' performance in behavioral tests, enrichment (regardless of cage size) did significantly benefit reproductive performance; pups from non-enriched cages weighed less than pups from enriched cages, and fewer survived to weaning age.

  19. PhAP protease from Pseudoalteromonas haloplanktis TAC125: Gene cloning, recombinant production in E. coli and enzyme characterization

    NASA Astrophysics Data System (ADS)

    de Pascale, D.; Giuliani, M.; De Santi, C.; Bergamasco, N.; Amoresano, A.; Carpentieri, A.; Parrilli, E.; Tutino, M. L.

    2010-08-01

    Cold-adapted proteases have been found to be the dominant activity throughout the cold marine environment, indicating their importance in bacterial acquisition of nitrogen-rich complex organic compounds. However, few extracellular proteases from marine organisms have been characterized so far, and the mechanisms that enable their activity in situ are still largely unknown. Aside from their ecological importance and use as model enzyme for structure/function investigations, cold-active proteolytic enzymes offer great potential for biotechnological applications. Our studies on cold adapted proteases were performed on exo-enzyme produced by the Antarctic marine bacterium Pseudoalteromonas haloplanktis TAC125. By applying a proteomic approach, we identified several proteolytic activities from its culture supernatant. PhAP protease was selected for further investigations. The encoding gene was cloned and the protein was recombinantly produced in E. coli cells. The homogeneous product was biochemically characterised and it turned out that the enzyme is a Zn-dependent aminopeptidase, with an activity dependence from assay temperature typical of psychrophilic enzymes.

  20. Cytoplasmic and Periplasmic Proteomic Signatures of Exponentially Growing Cells of the Psychrophilic Bacterium Pseudoalteromonas haloplanktis TAC125 ▿ †

    PubMed Central

    Wilmes, Boris; Kock, Holger; Glagla, Susanne; Albrecht, Dirk; Voigt, Birgit; Markert, Stephanie; Gardebrecht, Antje; Bode, Rüdiger; Danchin, Antoine; Feller, Georges; Hecker, Michael; Schweder, Thomas

    2011-01-01

    The psychrophilic model bacterium Pseudoalteromonas haloplanktis is characterized by remarkably fast growth rates under low-temperature conditions in a range from 5°C to 20°C. In this study the proteome of cellular compartments, the cytoplasm and periplasm, of P. haloplanktis strain TAC125 was analyzed under exponential growth conditions at a permissive temperature of 16°C. By means of two-dimensional protein gel electrophoresis and mass spectrometry, a first inventory of the most abundant cytoplasmic and periplasmic proteins expressed in a peptone-supplemented minimal medium was established. By this approach major enzymes of the amino acid catabolism of this marine bacterium could be functionally deduced. The cytoplasmic proteome showed a predominance of amino acid degradation pathways and tricarboxylic acid (TCA) cycle enzymes but also the protein synthesis machinery. Furthermore, high levels of cold acclimation and oxidative stress proteins could be detected at this moderate growth temperature. The periplasmic proteome was characterized by a significant abundance of transporters, especially of highly expressed putative TonB-dependent receptors. This high capacity for protein synthesis, efficient amino acid utilization, and substrate transport may contribute to the fast growth rates of the copiotrophic bacterium P. haloplanktis in its natural environments. PMID:21183643

  1. La limite Crétacé/Tertiaire dans le Sud-Ouest du Petén (Guatemala)

    NASA Astrophysics Data System (ADS)

    Fourcade, Eric; Alonzo, Marlon; Barrillas, Manolo; Bellier, Jean-Pierre; Bonneau, Michel; Cosillo, Alan; Cros, Pierre; Debrabant, Pierre; Gardin, Silvia; Masure, Edwige; Philip, Jean; Renard, Maurice; Rocchia, Robert; Romero, Jorge

    1997-07-01

    Au Petén, entre les calcaires à grands foraminifères, algues et rudistes du Maastrichtien et les calcaires, marnes et argiles à foraminifères planctoniques et nannofossiles calcaires du Danien inférieur, affleurent soit des brèches à clastes de calcaires de plate-forme comme à El Caribe, soit une surface ferrugineuse comme à El Ceibo. L'origine des brèches a fait l'objet de controverses: tsunami dû à l'impact de la météorite de la limite Crétacé / Tertiaire sur le Yucatán versus baisse du niveau marin. La coupe d'El Ceibo fournit des données qui n'incitent pas à retenir pour ces brèches une origine liée à la vague d'impact. La comparaison des deux coupes plaiderait en faveur d'une origine tectonique.

  2. Using Tic-Tac software to reduce anxiety-related behaviour in adults with autism and learning difficulties during waiting periods: a pilot study.

    PubMed

    Campillo, Cristina; Herrera, Gerardo; Remírez de Ganuza, Conchi; Cuesta, José L; Abellán, Raquel; Campos, Arturo; Navarro, Ignacio; Sevilla, Javier; Pardo, Carlos; Amati, Fabián

    2014-04-01

    Deficits in the perception of time and processing of changes across time are commonly observed in individuals with autism. This pilot study evaluated the efficacy of the use of the software tool Tic-Tac, designed to make time visual, in three adults with autism and learning difficulties. This research focused on applying the tool in waiting situations where the participants exhibited anxiety-related behaviour. The intervention followed a baseline and intervention (AB) design, and a partial interval recording procedure was used to code the presence of stereotypes, nervous utterances, wandering or other examples of nervousness during the selected waiting situations. The results showed that the use of Tic-Tac resulted in lower levels of anxiety-related behaviour in all three participants, compared to the baseline, suggesting that this software may be an effective technology for helping people with autism with organisation and predictability during waiting periods. The results are discussed in terms of limitations and implications for further study.

  3. Endocrine MPA enhances the effects of TAC chemotherapy on improvement of prognosis and increase in long-term survival rates for patients with endometrial cancer.

    PubMed

    Yuan, Xiuhong; Wang, L U; Xue, Juan; Li, L I; Zhang, Jing

    2015-09-01

    The aim of the present study was to investigate the effect of taxol, adriamycin and carboplatin (TAC) chemotherapy combined with endocrine medroxyprogesterone acetate (MPA) therapy for the treatment of patients with endometrial cancer. A retrospective analysis of 124 patients with endometrial cancer was performed by dividing the cohort into an experimental and control group. The 64 patients in the experimental group received TAC and MPA chemotherapy, whereas the 60 patients in the control group were treated with TAC chemotherapy only. Tissue samples scraped from the uterus were used to extract the total proteins and RNAs for the western blot and reverse transcription-quantitative polymerase chain reaction analyses, respectively. All the patients were followed up for 20-45 months, during which time prognostic data, and one- to three-year survival rates were recorded and compared. The rate of recurrence or metastasis was significantly lower in the experimental group compared with that in the control group (P<0.05) and the three-year survival rate of the experimental group was significantly higher than that of the control group (P<0.05). Furthermore, the mean metastasis-associated 1 (MTA1) protein and RNA expression levels were significantly lower in the experimental group compared with the control group (P<0.05), exhibiting ~30 and ~15% of the levels in the control group, respectively. Therefore, a treatment strategy of TAC chemotherapy combined with endocrine MPA therapy appears to effectively improve the prognosis and increase the long-term survival rates of patients with endometrial cancer. Such an enhancing effect may be mediated by the transcriptional downregulation of MTA1 expression.

  4. An open-label, randomized, multicenter dose-finding study of once-per-cycle pegfilgrastim versus daily filgrastim in Chinese breast cancer patients receiving TAC chemotherapy.

    PubMed

    Zhang, Wei; Jiang, Zhiwei; Wang, Ling; Li, Chanjuan; Xia, Jielai

    2015-05-01

    A chemotherapy regimen of docetaxel, doxorubicin and cyclophosphamide (TAC) has been accepted as a standard care because of their superior clinical benefit in early-stage breast cancer patients, but with a higher risk of neutropenia. Pegfilgrastim is a once-per-cycle therapy for prophylactic neutrophil support and neutropenia prevention. There was still a lack of direct evidences for finding an optimal fixed dose of pegfilgrastim in Chinese breast cancer patients receiving TAC regimen. An open-label, randomized, phase II study was designed to compare the effects of pegfilgrastim with filgrastim. Eighteen centers in China enrolled 171 eligible female breast cancer patients with cycles of TAC chemotherapy treatment, randomized into four arms, received a single subcutaneous injection of pegfilgrastim (60, 100 or 120 µg/kg) per chemotherapy cycle or daily subcutaneous injections of filgrastim 5 µg/kg 24 h after chemotherapy. Efficacy and safety were analyzed. In ITT population, the mean duration of grade 3+ neutropenia (neutrophil count <1.0 × 10(9)/l) was 2.09, 1.53 and 1.73 days in patients who received pegfilgrastim 60, 100 and 120 µg/kg/cycle, respectively, and 1.69 days in patients who received 5 µg/kg/day filgrastim (P = 0.043). The incidence of grade 3+ neutropenia was 76, 83 and 74 % for doses of pegfilgrastim and 90 % for filgrastim (P = 0.409). The results for febrile neutropenia, time to neutrophil recovery and neutrophil profile were also not significantly different between arms. The safety profiles of pegfilgrastim and filgrastim were similar. A single dose of 100 µg/kg once-per-cycle administration of pegfilgrastim provided neutrophil support and a safety profile comparable to daily subcutaneous injections of filgrastim in Chinese breast cancer patients receiving TAC chemotherapy.

  5. Pseudomonas savastanoi pv. savastanoi contains two iaaL paralogs, one of which exhibits a variable number of a trinucleotide (TAC) tandem repeat.

    PubMed

    Matas, Isabel M; Pérez-Martínez, Isabel; Quesada, José M; Rodríguez-Herva, José J; Penyalver, Ramón; Ramos, Cayo

    2009-02-01

    In this study, Pseudomonas savastanoi pv. savastanoi isolates were demonstrated to contain two iaaL paralogs, which are both chromosomally located in most strains. Comparative analysis of iaaL nucleotide sequences amplified from these two paralogs revealed that one paralog, iaaL(Psn), is 100% identical to iaaL from P. savastanoi pv. nerii, while the other paralog, iaaL(Psv), exhibited 93% identity to iaaL from Pseudomonas syringae pv. tomato (iaaL(Pto)). A 3-nucleotide motif (TAC) comprised of 3 to 15 repeats, which remained stable after propagation of the strains in olive plants, was found in iaaL(Psv). Based on the observed nucleotide sequence variations, a restriction fragment length polymorphism assay was developed that allowed differentiation among iaaL(Psn), iaaL(Psv), and iaaL(Pto)(.) In addition, reverse transcriptase PCR on total RNA from P. savastanoi pv. savastanoi strains demonstrated that both iaaL(Psv) and iaaL(Psn) containing 14 or fewer TAC repeats are transcribed. Capillary electrophoresis analysis of PCR-amplified DNA fragments containing the TAC repeats from iaaL(Psv) allowed the differentiation of P. savastanoi pv. savastanoi isolates.

  6. Estimation of radiation effects in the front-end electronics of an ILC electromagnetic calorimeter

    NASA Astrophysics Data System (ADS)

    Bartsch, V.; Postranecky, M.; Targett-Adams, C.; Warren, M.; Wing, M.

    2008-08-01

    The front-end electronics of the electromagnetic calorimeter of an International Linear Collider detector are situated in a radiation environment. This requires the effect of the radiation on the performance of the electronics, specifically FPGAs, to be examined. In this paper we study the flux, particle spectra and deposited doses at the front-end electronics of the electromagnetic calorimeter of a detector at the ILC. We also study the occupancy of the electromagnetic calorimeter. These estimates are compared with measurements, e.g. of the radiation damage of FPGAs, done elsewhere. The outcome of the study shows that the radiation doses and the annual flux is low enough to allow today's FPGAs to operate. The Single Event Upset rate, however, lies between 14 min and 12 h depending on the FPGA used and therefore needs to be considered in the design of the data acquisition system of the electromagnetic calorimeter. The occupancy is about 0.002 per bunch train not taking into account the effect of noise which depends on the choice of the detector.

  7. Phase-I trigger readout electronics upgrade of the ATLAS liquid-argon calorimeters

    NASA Astrophysics Data System (ADS)

    Mori, Tatsuya

    2016-09-01

    This article gives an overview of the Phase-I Upgrade of the ATLAS LAr Calorimeter Trigger Readout. The design of custom developed hardware for fast real-time data processing and transfer are presented. Performance results from the prototype boards operated in the demonstrator system, first measurements of noise behavior and responses on the test pulses to the demonstrator system are shown.

  8. A liquid hydrogen target for the calibration of the MEG and MEG II liquid xenon calorimeter

    NASA Astrophysics Data System (ADS)

    Signorelli, G.; Baldini, A. M.; Bemporad, C.; Cei, F.; Nicolò, D.; Galli, L.; Gallucci, G.; Grassi, M.; Papa, A.; Sergiampietri, F.; Venturini, M.

    2016-07-01

    We designed, built and operated a liquid hydrogen target for the calibration of the liquid xenon calorimeter of the MEG experiment. The target was used throughout the entire data taking period, from 2008 to 2013 and it is being refurbished and partly re-designed to be integrated and used in the MEG-II experiment.

  9. A fast calorimeter simulation for SSC (Superconducting Super Collider) detector design

    SciTech Connect

    Newman-Holmes, C.; Freeman, J.

    1987-12-01

    We have developed a fast and easily varied simulation of a ''generic'' 4..pi.. calorimeter. The program enables one to study the gross features of detector response for various physics processes. The simulation program is described and some examples of its use are presented. 3 refs., 6 figs.

  10. Design studies of the PWO Forward End-cap calorimeter for P¯ANDA

    NASA Astrophysics Data System (ADS)

    Moeini, H.; Al-Turany, M.; Babai, M.; Biegun, A.; Bondarenko, O.; Götzen, K.; Kavatsyuk, M.; Lindemulder, M. F.; Löhner, H.; Melnychuk, D.; Messchendorp, J. G.; Smit, H. A. J.; Spataro, S.; Veenstra, R.

    2013-11-01

    The P¯ANDA detection system at FAIR, Germany, is designed to study antiproton-proton annihilations, in order to investigate, among others, the realm of charm-meson states and glueballs, which has still much to reveal. The yet unknown properties of this field are to be unraveled through studying QCD phenomena in the non-perturbative regime. The multipurpose P¯ANDA detector will be capable of tracking, calorimetry, and particle identification, and is planned to run at high luminosities providing average reaction rates up to 2 · 107 interactions/s. The envisaged physics program requires measurements of photons and charged particles with excellent energy, position, and time resolutions. The electromagnetic calorimeter (EMC) will serve as one of the basic components of the detector setup and comprises cooled lead-tungstate (PbWO4) crystals. This paper presents the mechanical design of the Forward End-cap calorimeter and analyzes the response of the Forward End-cap calorimeter in conjunction with the full EMC and the complete P¯ANDA detector. The simulation studies are focused on the performance of the planned EMC with respect to the energy and spatial resolution of the reconstructed photons. Results of the Monte Carlo simulations, excluding very low-energy photons, have been validated by data obtained from a prototype calorimeter and shown to fulfil the requirements imposed by the P¯ANDA physics program.

  11. Processing of the signals from the Liquid Xenon Calorimeter for timing measurements

    NASA Astrophysics Data System (ADS)

    Epshteyn, L. B.; Grebenuyk, A. A.; Kozyrev, A. N.; Logashenko, I. B.; Mikhaylov, K. Yu.; Ruban, A. A.; Yudin, Yu. V.

    2017-02-01

    One of the goals of the Cryogenic Magnetic Detector at Budker Institute of Nuclear Physics SB RAS (Novosibirsk, Russia) is a study of hadron production in electron-positron collisions near threshold. The neutron-antineutron pair production events can be detected only by the calorimeters. In the barrel calorimeter the antineutron annihilation typically occurs about 5 ns or later after the beams crossing. For identification of such events it is necessary to measure the time of flight of particles to the LXe-calorimeter with an accuracy of about a few nanoseconds. The LXe-calorimeter consists of 14 layers of ionization chambers with two readout: anode and cathode. The duration of charge collection to the anodes is about 4.5 μs, while the required accuracy of measuring of the signal arrival time is less than 1/1000 of that (i.e. 4.5 ns). Besides, the signals' shapes differ substantially from event to event, so the signal arrival time is measured in two stages. In the paper we describ the development of the special electronics which performs waveform digitization and the on-line measurement of signals' arrival times and amplitudes.

  12. Sensing disks for slug-type calorimeters have higher temperature stability

    NASA Technical Reports Server (NTRS)

    1967-01-01

    Graphite sensing disk for slug-type radiation calorimeters exhibits better performance at high temperatures than copper and nickel disks. The graphite is heat-soaked to stabilize its emittance and the thermocouple is protected from the graphite so repeated temperature cycling does not change its sensitivity.

  13. A Scintillator tile-fiber preshower detector for the CDF Central Calorimeter

    SciTech Connect

    S. Lami

    2004-08-12

    The front face of the CDF central calorimeter is being equipped with a new Preshower detector, based on scintillator tiles read out by WLS fibers. A light yield of about 40 pe/MIP at the tile exit was obtained, exceeding the design requirements.

  14. Windows Calorimeter Control (WinCal) program computer software configuration management plan

    SciTech Connect

    1997-03-26

    This document describes the system configuration management activities performed in support of the Windows Calorimeter Control (WinCal) system, in accordance with Site procedures based on Institute of Electrical and Electronic Engineers (IEEE) Standard 828-1990, Standard for Software Configuration Management Plans (IEEE 1990) and IEEE Standard 1042-1987, Guide to Software Configuration Management (IEEE 1987).

  15. Calibration of the CDF tile-fiber endplug calorimeters using moving radioactive sources

    SciTech Connect

    Barnes, V.; Laasanen, A.; Pompos, A.; Wilson, M.

    1998-11-01

    The use of moving radioactive gamma sources to assess, calibrate and monitor scintillating tile calorimeters is discussed, and the techniques and equipment are described. The capabilities of the technique are illustrated using Cs{sup 137} sources with the CDF Endplug Upgrade EM and Hadron calorimeters at testbeams and at a cosmic ray test stand. Source measurements of all the tiles in testbeam modules which are exact replicas of the calorimeters, predict the relative responses of EM towers to 50 GeV positrons and muons, and of Hadron towers to 50 GeV pions, with RMS accuracies of 1.3{percent}, 1.8{percent} and 2.0{percent}, respectively. Source measurements will be used in lieu of testbeam measurements for the initial calibration of all towers in the final calorimeters. Source measurements of single tiles are reproducible to 0.4{percent} and will be used to monitor gain changes of the photomultiplier tubes. {copyright} {ital 1998 American Institute of Physics.}

  16. Simulation of π0-γ separation study for proposed CMS forward electromagnetic calorimeter

    DOE PAGES

    Roy, Ashim; Jain, Shilpi; Banerjee, Sunanda; ...

    2016-11-11

    The Forward Electromagnetic Calorimeter of the CMS detector is going to be upgraded in the high luminosity running as the energy of the present Electromagnetic Calorimeter (PbWO4) will degrade in the high luminosity (luminosity 1034 cm-2 s-1) running due to extensive radiation (hadron flux 1013 neutrons cm,-2). Shashlik Electromagnetic Calorimeter which consists of alternate layers of 1.5 mm LYSO(Ce) crystal plates and 2.5 mm Tungsten absorbers, was a proposal for high luminosity running. One of the performance points for any electromagnetic calorimeter is the ability to separate π0 s from true photons, since final states with photons are a cleanmore » and one of the most important final states in proton-proton collisions at the LHC. As a result, the objective of this project is to study the possibility of π0 and γ separation in the Shashlik detector using Multivariate Analysis (MVA) technique.« less

  17. A flow calorimeter for determining combustion efficiency from residual enthalpy of exhaust gases

    NASA Technical Reports Server (NTRS)

    Evans, Albert; Hibbard, Robert R

    1954-01-01

    A flow calorimeter for determining the combustion efficiency of turbojet and ram-jet combustors from measurement of the residual enthalpy of combustion of the exhaust gas is described. Briefly, the calorimeter catalytically oxidizes the combustible constituents of exhaust-gas samples, and the resultant temperature rise is measured. This temperature rise is related to the residual enthalpy of combustion of the sample by previous calibration of the calorimeter. Combustion efficiency can be calculated from a knowledge of the residual enthalpy of the exhaust gas and the combustor input enthalpy. An accuracy of +-0.2 Btu per cubic foot was obtained with prepared fuel-air mixtures, and the combustion efficiencies of single turbojet combustors measured by both the flow-calorimeter and heat-balance methods compared within 3 percentage units. Flow calorimetry appears to be a suitable method for determining combustion efficiencies at high combustor temperatures where ordinary thermocouples cannot be used. The method is fundamentally more accurate than heat-balance methods at high combustion efficiencies and can be used to verify near-100-percent efficiency data.

  18. Fast-acting calorimeter measures heat output of plasma gun accelerator

    NASA Technical Reports Server (NTRS)

    Dethlefson, R.; Larson, A. V.; Liebing, L.

    1967-01-01

    Calorimeter measures the exhaust energy from a shot of a pulsed plasma gun accelerator. It has a fast response time and requires only one measurement to determine the total energy. It uses a long ribbon of copper foil wound around a glass frame to form a reentrant cavity.

  19. A Simple Rate Law Experiment Using a Custom-Built Isothermal Heat Conduction Calorimeter

    ERIC Educational Resources Information Center

    Wadso, Lars; Li, Xi.

    2008-01-01

    Most processes (whether physical, chemical, or biological) produce or consume heat: measuring thermal power (the heat production rate) is therefore a typical method of studying processes. Here we describe the design of a simple isothermal heat conduction calorimeter built for use in teaching; we also provide an example of its use in simultaneously…

  20. 16 CFR Figure 1 to Part 1633 - Test Assembly, Shown in Furniture Calorimeter (Configuration A)

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Test Assembly, Shown in Furniture Calorimeter (Configuration A) 1 Figure 1 to Part 1633 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FLAMMABLE FABRICS ACT REGULATIONS STANDARD FOR THE FLAMMABILITY (OPEN FLAME) OF MATTRESS SETS Pt.1633,...

  1. 16 CFR Figure 1 to Part 1633 - Test Assembly, Shown in Furniture Calorimeter (Configuration A)

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 16 Commercial Practices 2 2013-01-01 2013-01-01 false Test Assembly, Shown in Furniture Calorimeter (Configuration A) 1 Figure 1 to Part 1633 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FLAMMABLE FABRICS ACT REGULATIONS STANDARD FOR THE FLAMMABILITY (OPEN FLAME) OF MATTRESS SETS Pt. 1633,...

  2. 16 CFR Figure 1 to Part 1633 - Test Assembly, Shown in Furniture Calorimeter (Configuration A)

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Test Assembly, Shown in Furniture Calorimeter (Configuration A) 1 Figure 1 to Part 1633 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FLAMMABLE FABRICS ACT REGULATIONS STANDARD FOR THE FLAMMABILITY (OPEN FLAME) OF MATTRESS SETS Pt. 1633,...

  3. 16 CFR Figure 1 to Part 1633 - Test Assembly, Shown in Furniture Calorimeter (Configuration A)

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Test Assembly, Shown in Furniture Calorimeter (Configuration A) 1 Figure 1 to Part 1633 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FLAMMABLE FABRICS ACT REGULATIONS STANDARD FOR THE FLAMMABILITY (OPEN FLAME) OF MATTRESS SETS Pt.1633,...

  4. 16 CFR Figure 1 to Part 1633 - Test Assembly, Shown in Furniture Calorimeter (Configuration A)

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Test Assembly, Shown in Furniture Calorimeter (Configuration A) 1 Figure 1 to Part 1633 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FLAMMABLE FABRICS ACT REGULATIONS STANDARD FOR THE FLAMMABILITY (OPEN FLAME) OF MATTRESS SETS Pt.1633,...

  5. An electromagnetic calorimeter for the solenoidal tracker at the Relativistic Heavy Ion Collider

    SciTech Connect

    Westfall, G.D.; Llope, W.J.; Underwood, D.G.

    1993-10-01

    In this document, we outline a proposal to the National Science Foundation (NSF) for the construction of an electromagnetic calorimeter for STAR that fulfills these requirements. This proposal creates the opportunity for the NSF to make a major impact on the experimental program at RHIC by providing a crucial, but defensibly omitted, component of the STAR experiment as approved.

  6. Investigating Freezing Point Depression and Cirrus Cloud Nucleation Mechanisms Using a Differential Scanning Calorimeter

    ERIC Educational Resources Information Center

    Bodzewski, Kentaro Y.; Caylor, Ryan L.; Comstock, Ashley M.; Hadley, Austin T.; Imholt, Felisha M.; Kirwan, Kory D.; Oyama, Kira S.; Wise, Matthew E.

    2016-01-01

    A differential scanning calorimeter was used to study homogeneous nucleation of ice from micron-sized aqueous ammonium sulfate aerosol particles. It is important to understand the conditions at which these particles nucleate ice because of their connection to cirrus cloud formation. Additionally, the concept of freezing point depression, a topic…

  7. Windows Calorimeter Control (WinCal) program computer software design description

    SciTech Connect

    Pertzborn, N.F.

    1997-03-26

    The Windows Calorimeter Control (WinCal) Program System Design Description contains a discussion of the design details for the WinCal product. Information in this document will assist a developer in maintaining the WinCal system. The content of this document follows the guidance in WHC-CM-3-10, Software Engineering Standards, Standard for Software User Documentation.

  8. Power loss measurement of implantable wireless power transfer components using a Peltier device balance calorimeter

    NASA Astrophysics Data System (ADS)

    Leung, Ho Yan; Budgett, David M.; Taberner, Andrew; Hu, Patrick

    2014-09-01

    Determining heat losses in power transfer components operating at high frequencies for implantable inductive power transfer systems is important for assessing whether the heat dissipated by the component is acceptable for implantation and medical use. However, this is a challenge at high frequencies and voltages due to limitations in electronic instrumentation. Calorimetric methods of power measurement are immune to the effects of high frequencies and voltages; hence, the measurement is independent of the electrical characteristics of the system. Calorimeters have been widely used to measure the losses of high power electrical components (>50 W), however it is more difficult to perform on low power components. This paper presents a novel power measurement method for components dissipating anywhere between 0.2 W and 1 W of power based on a heat balance calorimeter that uses a Peltier device as a balance sensor. The proposed balance calorimeter has a single test accuracy of ±0.042 W. The experimental results revealed that there was up to 35% difference between the power measurements obtained with electrical methods and the proposed calorimeter.

  9. Performance of the ATLAS Tile Hadronic Calorimeter at LHC in Run 1 and planned upgrades

    NASA Astrophysics Data System (ADS)

    Solovyanov, O.

    2014-10-01

    The Tile Calorimeter (TileCal) is the central section of the ATLAS hadronic calorimeter at the Large Hadron Collider, a key detector for the measurements of hadrons, jets, tau leptons and missing transverse energy. Scintillation light produced in the tiles is transmitted by wavelength shifting fibres to photomultiplier tubes (PMTs). The resulting electronic signals from approximately 10000 PMTs are digitized before being transferred to off-detector data-acquisition systems. The data quality procedures used during the LHC data-taking and the evolution of the detector status are explained in the presentation. The energy and the time reconstruction performance of the digitized signals is presented and the noise behaviour and its improvement during the detector consolidation in maintenance periods are shown. A set of calibration systems allow monitoring and equalization of the calorimeter channels responses via signal sources that act at every stage of the signal path, from scintillation light to digitized signal. These partially overlapping systems are described in detail, their individual performance is discussed as well as the comparative results from measurements of the evolution of the calorimeter response with time during the full LHC data-taking period. The TileCal upgrade aims at replacing the majority of the on- and off-detector electronics so that all calorimeter signals will be directly digitized and sent to the off-detector electronics in the counting room. To achieve the required reliability, redundancy has been introduced at different levels. For the off-detector electronics a special pre-processor board is being developed, which will take care of the initial trigger processing, while the main data are temporarily stored in the pipeline and de-randomiser memories.

  10. Theory and Development of Position-Sensitive Quantum Calorimeters. Degree awarded by Stanford Univ.

    NASA Technical Reports Server (NTRS)

    Figueroa-Feliciano, Enectali; White, Nicholas E. (Technical Monitor)

    2001-01-01

    Quantum calorimeters are being developed as imaging spectrometers for future X-ray astrophysics observatories. Much of the science to be done by these instruments could benefit greatly from larger focal-plane coverage of the detector (without increasing pixel size). An order of magnitude more area will greatly increase the science throughput of these future instruments. One of the main deterrents to achieving this goal is the complexity of the readout schemes involved. We have devised a way to increase the number of pixels from the current baseline designs by an order of magnitude without increasing the number of channels required for readout. The instrument is a high energy resolution, distributed-readout imaging spectrometer called a Position-Sensitive Transition-Edge Sensor (POST). A POST is a quantum calorimeter consisting of two Transition-Edge Sensors (TESS) on the ends of a long absorber capable of one-dimensional imaging spectroscopy. Comparing rise time and energy information from the two TESS, the position of the event in the POST is determined. The energy of the event is inferred from the sum of the two pulses. We have developed a generalized theoretical formalism for distributed-readout calorimeters and apply it to our devices. We derive the noise theory and calculate the theoretical energy resolution of a POST. Our calculations show that a 7-pixel POST with 6 keV saturation energy can achieve 2.3 eV resolution, making this a competitive design for future quantum calorimeter instruments. For this thesis we fabricated 7- and 15-pixel POSTS using Mo/Au TESs and gold absorbers, and moved from concept drawings on scraps of napkins to a 32 eV energy resolution at 1.5 keV, 7-pixel POST calorimeter.

  11. Radiation hardness study of Silicon Detectors for the CMS High Granularity Calorimeter (HGCAL)

    NASA Astrophysics Data System (ADS)

    Currás, E.; Mannelli, M.; Moll, M.; Nourbakhsh, S.; Steinbrueck, G.; Vila, I.

    2017-02-01

    The high luminosity LHC (HL-LHC or Phase-II) is expected to increase the instantaneous luminosity of the LHC by a factor of about five, delivering 0~25 fb ‑1 per year between 2025 and 2035. Under these conditions the performance degradation of detectors due to integrated radiation dose/fluence will need to be addressed. The CMS collaboration is planning to upgrade many detector components, including the forward calorimeters. The replacement for the existing endcap preshower, electromagnetic and hadronic calorimeters is called the High Granularity Calorimeter (HGCAL) and it will be realized as a sampling calorimeter, including 40 layers of silicon detectors totalling 600 m2. The sensors will be realized as pad detectors with cell size between 0.5 and 1.0 cm2 and an active thickness between 100 μm and 300 μm depending on their location in the endcaps. The thinner sensors will be used in the highest radiation environment. For an integrated luminosity of 3000 fb ‑1, the electromagnetic calorimeter will have to sustain a maximum integrated dose of 1.5 MGy and neutron fluences of 1.0×1016 neq/cm2. A tolerance study after neutron irradiation of 300 μm, 200 μm, 100 μm and 50 μm n-on-p and p-on-n silicon pads irradiated to fluences up to 1.6×1016 neq/cm2 is presented. The main properties of these diodes have been studied before and after irradiation: leakage current, capacitance, charge collection efficiency with laser and sensitivity to minimum ionizing particles with radioactive source (90Sr). The results show a good performance even after the most extreme irradiation.

  12. Atmospheric absorption cell characterization

    NASA Astrophysics Data System (ADS)

    1982-06-01

    The measurement capability of the Avionics Laboratory IR Facility was used to evaluate an absorption cell that will be used to simulate atmospheric absorption over horizontal paths of 1 - 10 km in length. Band models were used to characterize the transmittance of carbon dioxide (CO2), nitrogen (N2), and nitrous oxide (N2O) in the cell. The measured transmittance was compared to the calculated values. Nitrous oxide is important in the 4 - 4.5 micron range in shaping the weak line absorption of carbon dioxide. The absorption cell is adequate for simulating atmospheric absorption over these paths.

  13. Observation and Simulations of the Backsplash Effects in High-Energy Gamma-Ray Telescopes Containing a Massive Calorimeter

    NASA Technical Reports Server (NTRS)

    Moiseev, Alexander A.; Ormes, Jonathan F.; Hartman, Robert C.; Johnson, Thomas E.; Mitchell, John W.; Thompson, David J.

    1999-01-01

    Beam test and simulation results are presented for a study of the backsplash effects produced in a high-energy gamma-ray detector containing a massive calorimeter. An empirical formula is developed to estimate the probability (per unit area) of backsplash for different calorimeter materials and thicknesses, different incident particle energies, and at different distances from the calorimeter. The results obtained are applied to the design of Anti-Coincidence Detector (ACD) for the Large Area Telescope (LAT) on the Gamma-ray Large Area Space Telescope (GLAST).

  14. Correlation between the expression of S100A4 and the efficacy of TAC neoadjuvant chemotherapy in breast cancer.

    PubMed

    Li, Wen-Lei; Zhang, Yang; Liu, Bao-Guo; DU, Qian; Zhou, Chang-Xin; Tian, Xing-Song

    2015-11-01

    The aim of this study was to investigate the correlation between the expression of S100A4 and the efficacy of neoadjuvant chemotherapy in breast cancer. A total of 65 patients with invasive breast cancer were treated with neoadjuvant chemotherapy using the TAC regimen. The expression of S100A4 was detected by an immunohistochemical two-step method prior to treatment, after 2 cycles of chemotherapy and after 4 cycles of chemotherapy. Pathological evaluations of the chemotherapy were performed using the Miller and Payne (MP) grading system and their correlation with the changes of S100A4 expression during and after the treatment were explored. Between pre-neoadjuvant chemotherapy and 4 cycles post-chemotherapy, there was a significant difference in the expression of S100A4 (P<0.05); S100A4 expression was associated with neoadjuvant chemotherapy. However, between pre-neoadjuvant chemotherapy and 2 cycles post-chemotherapy, there was no significant difference in the expression of S100A4 (P>0.05). The intensity and changes of S100A4 expression were positively correlated with the efficacy of neoadjuvant chemotherapy (r=0.259, P<0.05). When patients with an MP grade of I or II following the second cycle of neoadjuvant chemotherapy were continually treated with the original chemotherapy for another 2 cycles, the desired effect was generally not achieved. S100A4 may be used as a predictor of the efficacy of neoadjuvant chemotherapy in breast cancer, guiding the formulation of individualized programs to improve the effectiveness of the treatment. For patients with an MP grade level of I or II after 2 cycles of neoadjuvant chemotherapy, the use of alternative chemotherapy regimens should be considered.

  15. Cationic starch (Q-TAC) pre-treatment of cotton fabric: influence on dyeing with reactive dye.

    PubMed

    Ali, Shamshad; Mughal, Mohsin Ali; Shoukat, Umair; Baloch, Mansoor Ali; Kim, Seong Hun

    2015-03-06

    Reactive dyes require high concentrations of an electrolyte to improve dye-fiber interaction, leading to the discharge of harmful effluent. One approach to reduce this unsafe release is treatment of the cotton fabric with cationic chemical reagents. This paper reports on the treatment of cotton fabric with cationic starch (Q-TAC), a commercial product, by batchwise method and pad batch method for the first time prior to reactive dyeing process. Furthermore,three commercial reactive dyes, based on monochloro triazine, vinyl sulfone and monochlorotriazine + vinyl sulfonechemistry, was applied on the cotton fabrics by continuous (pad-dry-cure) method. The treated cotton fabric by batchwise method produced 70% higher color yield (K/S) and 20% enhanced dye fixation (%F) than the untreated cotton fabric. X-ray photoelectron spectrometer (XPS) analysis revealed the presence of N1s peaks in the treated cotton fabrics. The crystallinity of treated cotton fabrics was reduced in comparison to untreated cotton fabric as revealed by wide angle X-ray diffraction (WAXD) measurements. Field Emission Scanning Electron Microscopy (FE-SEM) showed that the surface of treated cotton fabrics was rougher than untreated cotton fabric due to the deposition of cationic starch. Attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectrum confirmed the existence of quaternary ammonium groups, N(+)(CH3)3, in the treated cotton fabrics. The analysis of color fastness tests demonstrated good to excellent ratings for treated cotton fabrics. In this way, cationic starch treatment of cotton fabric before reactive dyeing process has been proven potentially a more environmentally sustainable method than conventional dyeing method.

  16. GenTAC Registry Report: Gender Differences Among Individuals with Genetically-Triggered Thoracic Aortic Aneurysm and Dissection

    PubMed Central

    Holmes, Kathryn W.; Maslen, Cheryl L.; Kindem, Mark; Kroner, Barbara L.; Song, Howard K.; Ravekes, William; Dietz, H.C.; Weinsaft, Jonathan W.; Roman, Mary J.; Devereux, Richard B.; Pyeritz, Reed E.; Bavaria, Joseph; Milewski, Karianna; Milewicz, Dianna; LeMaire, Scott A.; Hendershot, Tabitha; Eagle, Kim A.; Tolunay, H. Eser; Desvigne-Nickens, Patrice; Silberbach, Michael

    2013-01-01

    Previous data suggest women are at increased risk of death from aortic dissection. Therefore, we analyzed data from the GenTAC registry, the NIH-sponsored program that collects information about individuals with genetically-triggered thoracic aortic aneurysms and cardiovascular conditions. We performed cross-sectional analyses in adults with Marfan syndrome (MFS), familial thoracic aortic aneurysm or dissection (FTAAD), bicuspid aortic valve (BAV) with thoracic aortic aneurysm or dissection, and subjects under 50 years of age with thoracic aortic aneurysm or dissection (TAAD<50y). Women comprised 32% of 1449 subjects and were 21% of subjects with BAV, 34% with FTAAD, 22% with TAAD <50y, and 47% with MFS. Thoracic aortic dissections occurred with equal gender frequency yet women with BAV had more extensive dissections. Aortic size was smaller in women but was similar after controlling for BSA. Age at operation for aortic valve dysfunction, aneurysm or dissection did not differ by gender. Multivariate analysis (adjusting for age, BSA, hypertension, study site, diabetes, and subgroup diagnoses) showed that women had fewer total aortic surgeries (OR= 0.65, p < 0.01) and were less likely to receive angiotensin converting enzyme inhibitors (ACEi) (OR=0.68, p < 0.05). As in BAV, other genetically-triggered aortic diseases such as FTAAD and TAAD<50 are more common in males. In women, decreased prevalence of aortic operations and less treatment with ACEi may be due to their smaller absolute aortic diameters. Longitudinal studies are needed to determine if women are at higher risk for adverse events. PMID:23444191

  17. Absolute x-ray dosimetry on a synchrotron medical beam line with a graphite calorimeter

    SciTech Connect

    Harty, P. D. Ramanathan, G.; Butler, D. J.; Johnston, P. N.; Lye, J. E.; Hall, C. J.; Stevenson, A. W.

    2014-05-15

    Purpose: The absolute dose rate of the Imaging and Medical Beamline (IMBL) on the Australian Synchrotron was measured with a graphite calorimeter. The calorimetry results were compared to measurements from the existing free-air chamber, to provide a robust determination of the absolute dose in the synchrotron beam and provide confidence in the first implementation of a graphite calorimeter on a synchrotron medical beam line. Methods: The graphite calorimeter has a core which rises in temperature when irradiated by the beam. A collimated x-ray beam from the synchrotron with well-defined edges was used to partially irradiate the core. Two filtration sets were used, one corresponding to an average beam energy of about 80 keV, with dose rate about 50 Gy/s, and the second filtration set corresponding to average beam energy of 90 keV, with dose rate about 20 Gy/s. The temperature rise from this beam was measured by a calibrated thermistor embedded in the core which was then converted to absorbed dose to graphite by multiplying the rise in temperature by the specific heat capacity for graphite and the ratio of cross-sectional areas of the core and beam. Conversion of the measured absorbed dose to graphite to absorbed dose to water was achieved using Monte Carlo calculations with the EGSnrc code. The air kerma measurements from the free-air chamber were converted to absorbed dose to water using the AAPM TG-61 protocol. Results: Absolute measurements of the IMBL dose rate were made using the graphite calorimeter and compared to measurements with the free-air chamber. The measurements were at three different depths in graphite and two different filtrations. The calorimetry measurements at depths in graphite show agreement within 1% with free-air chamber measurements, when converted to absorbed dose to water. The calorimetry at the surface and free-air chamber results show agreement of order 3% when converted to absorbed dose to water. The combined standard uncertainty is 3

  18. Spectroscopic Investigations of Highly Charged Ions using X-Ray Calorimeter Spectrometers

    SciTech Connect

    Thorn, Daniel Bristol

    2008-11-19

    Spectroscopy of K-shell transitions in highly charged heavy ions, like hydrogen-like uranium, has the potential to yield information about quantum electrodynamics (QED) in extremely strong nuclear fields as well as tests of the standard model, specifically parity violation in atomic systems. These measurements would represent the 'holy grail' in high-Z atomic spectroscopy. However, the current state-of-the-art detection schemes used for recording the K-shell spectra from highly charged heavy ions does not yet have the resolving power to be able to attain this goal. As such, to push the field of high-Z spectroscopy forward, new detectors must be found. Recently, x-ray calorimeter spectrometers have been developed that promise to make such measurements. In an effort to make the first steps towards attaining the 'holy grail', measurements have been performed with two x-ray calorimeter spectrometers (the XRS/EBIT and the ECS) designed and built at Goddard Space Flight Center in Greenbelt, MD. The calorimeter spectrometers have been used to record the K-shell spectra of highly charged ions produced in the SuperEBIT electron beam ion trap at Lawrence Livermore National Laboratory in Livermore, CA. Measurements performed with the XRS/EBIT calorimeter array found that the theoretical description of well-above threshold electron-impact excitation cross sections for hydrogen-like iron and nickel ions are correct. Furthermore, the first high-resolution spectrum of hydrogen-like through carbon-like praseodymium ions was recorded with a calorimeter. In addition, the new high-energy array on the EBIT Calorimeter Spectrometer (ECS) was used to resolve the K-shell x-ray emission spectrum of highly charged xenon ions, where a 40 ppm measurement of the energy of the K-shell resonance transition in helium-like xenon was achieved. This is the highest precision result, ever, for an element with such high atomic number. In addition, a first-of-its-kind measurement of the effect of the

  19. Experimental and numerical studies on heat flux measurements for the new types of calorimeters in the supersonic turbulent duct

    NASA Astrophysics Data System (ADS)

    Xu, Kao; Chen, Lianzhong; Liu, Xiang

    2016-10-01

    Heat flux measurements for new type of calorimeter were researched under the condition of the supersonic flow in the turbulent duct. The new type of calorimeter was the 0.4 mm gap between the heated end brim of slug and the test article. These calorimeters were uniformly installed on the test article with the length and width of 100mm ×100mm to measure the heat flux values. The results showed, under low pressures and small heat flux conditions, the measurement values of new type of calorimeters match well the traditional; Instead, under high pressures and larger heat flux conditions, the measurement values of the new type were more than that of the traditional; Meantime, the influence of the flow Match on the flow for the new type was researched based on the CFD simulation.

  20. Single hadron response measurement and calorimeter jet energy scale uncertainty with the ATLAS detector at the LHC

    NASA Astrophysics Data System (ADS)

    Aad, G.; Abbott, B.; Abdallah, J.; Abdelalim, A. A.; Abdesselam, A.; Abdinov, O.; Abi, B.; Abolins, M.; AbouZeid, O. S.; Abramowicz, H.; Abreu, H.; Acerbi, E.; Acharya, B. S.; Adamczyk, L.; Adams, D. L.; Addy, T. N.; Adelman, J.; Aderholz, M.; Adomeit, S.; Adragna, P.; Adye, T.; Aefsky, S.; Aguilar-Saavedra, J. A.; Aharrouche, M.; Ahlen, S. P.; Ahles, F.; Ahmad, A.; Ahsan, M.; Aielli, G.; Akdogan, T.; Åkesson, T. P. A.; Akimoto, G.; Akimov, A. V.; Akiyama, A.; Alam, M. S.; Alam, M. A.; Albert, J.; Albrand, S.; Aleksa, M.; Aleksandrov, I. N.; Alessandria, F.; Alexa, C.; Alexander, G.; Alexandre, G.; Alexopoulos, T.; Alhroob, M.; Aliev, M.; Alimonti, G.; Alison, J.; Aliyev, M.; Allbrooke, B. M. M.; Allport, P. P.; Allwood-Spiers, S. E.; Almond, J.; Aloisio, A.; Alon, R.; Alonso, A.; Alvarez Gonzalez, B.; Alviggi, M. G.; Amako, K.; Amaral, P.; Amelung, C.; Ammosov, V. V.; Amorim, A.; Amorós, G.; Amram, N.; Anastopoulos, C.; Ancu, L. S.; Andari, N.; Andeen, T.; Anders, C. F.; Anders, G.; Anderson, K. J.; Andreazza, A.; Andrei, V.; Andrieux, M.-L.; Anduaga, X. S.; Angerami, A.; Anghinolfi, F.; Anisenkov, A.; Anjos, N.; Annovi, A.; Antonaki, A.; Antonelli, M.; Antonov, A.; Antos, J.; Anulli, F.; Aoun, S.; Aperio Bella, L.; Apolle, R.; Arabidze, G.; Aracena, I.; Arai, Y.; Arce, A. T. H.; Arfaoui, S.; Arguin, J.-F.; Arik, E.; Arik, M.; Armbruster, A. J.; Arnaez, O.; Arnault, C.; Artamonov, A.; Artoni, G.; Arutinov, D.; Asai, S.; Asfandiyarov, R.; Ask, S.; Åsman, B.; Asquith, L.; Assamagan, K.; Astbury, A.; Astvatsatourov, A.; Aubert, B.; Auge, E.; Augsten, K.; Aurousseau, M.; Avolio, G.; Avramidou, R.; Axen, D.; Ay, C.; Azuelos, G.; Azuma, Y.; Baak, M. A.; Baccaglioni, G.; Bacci, C.; Bach, A. M.; Bachacou, H.; Bachas, K.; Backes, M.; Backhaus, M.; Badescu, E.; Bagnaia, P.; Bahinipati, S.; Bai, Y.; Bailey, D. C.; Bain, T.; Baines, J. T.; Baker, O. K.; Baker, M. D.; Baker, S.; Banas, E.; Banerjee, P.; Banerjee, Sw.; Banfi, D.; Bangert, A.; Bansal, V.; Bansil, H. S.; Barak, L.; Baranov, S. P.; Barashkou, A.; Barbaro Galtieri, A.; Barber, T.; Barberio, E. L.; Barberis, D.; Barbero, M.; Bardin, D. Y.; Barillari, T.; Barisonzi, M.; Barklow, T.; Barlow, N.; Barnett, B. M.; Barnett, R. M.; Baroncelli, A.; Barone, G.; Barr, A. J.; Barreiro, F.; Barreiro Guimarães da Costa, J.; Barrillon, P.; Bartoldus, R.; Barton, A. E.; Bartsch, V.; Bates, R. L.; Batkova, L.; Batley, J. R.; Battaglia, A.; Battistin, M.; Bauer, F.; Bawa, H. S.; Beale, S.; Beau, T.; Beauchemin, P. H.; Beccherle, R.; Bechtle, P.; Beck, H. P.; Becker, S.; Beckingham, M.; Becks, K. H.; Beddall, A. J.; Beddall, A.; Bedikian, S.; Bednyakov, V. A.; Bee, C. P.; Begel, M.; Behar Harpaz, S.; Behera, P. K.; Beimforde, M.; Belanger-Champagne, C.; Bell, P. J.; Bell, W. H.; Bella, G.; Bellagamba, L.; Bellina, F.; Bellomo, M.; Belloni, A.; Beloborodova, O.; Belotskiy, K.; Beltramello, O.; Ben Ami, S.; Benary, O.; Benchekroun, D.; Benchouk, C.; Bendel, M.; Benekos, N.; Benhammou, Y.; Benhar Noccioli, E.; Benitez Garcia, J. A.; Benjamin, D. P.; Benoit, M.; Bensinger, J. R.; Benslama, K.; Bentvelsen, S.; Berge, D.; Bergeaas Kuutmann, E.; Berger, N.; Berghaus, F.; Berglund, E.; Beringer, J.; Bernat, P.; Bernhard, R.; Bernius, C.; Berry, T.; Bertella, C.; Bertin, A.; Bertinelli, F.; Bertolucci, F.; Besana, M. I.; Besson, N.; Bethke, S.; Bhimji, W.; Bianchi, R. M.; Bianco, M.; Biebel, O.; Bieniek, S. P.; Bierwagen, K.; Biesiada, J.; Biglietti, M.; Bilokon, H.; Bindi, M.; Binet, S.; Bingul, A.; Bini, C.; Biscarat, C.; Bitenc, U.; Black, K. M.; Blair, R. E.; Blanchard, J.-B.; Blanchot, G.; Blazek, T.; Blocker, C.; Blocki, J.; Blondel, A.; Blum, W.; Blumenschein, U.; Bobbink, G. J.; Bobrovnikov, V. B.; Bocchetta, S. S.; Bocci, A.; Boddy, C. R.; Boehler, M.; Boek, J.; Boelaert, N.; Bogaerts, J. A.; Bogdanchikov, A.; Bogouch, A.; Bohm, C.; Boisvert, V.; Bold, T.; Boldea, V.; Bolnet, N. M.; Bona, M.; Bondarenko, V. G.; Bondioli, M.; Boonekamp, M.; Booth, C. N.; Bordoni, S.; Borer, C.; Borisov, A.; Borissov, G.; Borjanovic, I.; Borri, M.; Borroni, S.; Bortolotto, V.; Bos, K.; Boscherini, D.; Bosman, M.; Boterenbrood, H.; Botterill, D.; Bouchami, J.; Boudreau, J.; Bouhova-Thacker, E. V.; Boumediene, D.; Bourdarios, C.; Bousson, N.; Boveia, A.; Boyd, J.; Boyko, I. R.; Bozhko, N. I.; Bozovic-Jelisavcic, I.; Bracinik, J.; Braem, A.; Branchini, P.; Brandenburg, G. W.; Brandt, A.; Brandt, G.; Brandt, O.; Bratzler, U.; Brau, B.; Brau, J. E.; Braun, H. M.; Brelier, B.; Bremer, J.; Brenner, R.; Bressler, S.; Britton, D.; Brochu, F. M.; Brock, I.; Brock, R.; Brodbeck, T. J.; Brodet, E.; Broggi, F.; Bromberg, C.; Bronner, J.; Brooijmans, G.; Brooks, W. K.; Brown, G.; Brown, H.; Bruckman de Renstrom, P. A.; Bruncko, D.; Bruneliere, R.; Brunet, S.; Bruni, A.; Bruni, G.

    2013-03-01

    The uncertainty on the calorimeter energy response to jets of particles is derived for the ATLAS experiment at the Large Hadron Collider (LHC). First, the calorimeter response to single isolated charged hadrons is measured and compared to the Monte Carlo simulation using proton-proton collisions at centre-of-mass energies of sqrt{s} = 900 {GeV} and 7 TeV collected during 2009 and 2010. Then, using the decay of K s and Λ particles, the calorimeter response to specific types of particles (positively and negatively charged pions, protons, and anti-protons) is measured and compared to the Monte Carlo predictions. Finally, the jet energy scale uncertainty is determined by propagating the response uncertainty for single charged and neutral particles to jets. The response uncertainty is 2-5 % for central isolated hadrons and 1-3 % for the final calorimeter jet energy scale.