Prediction of Human Intestinal Absorption of Compounds Using Artificial Intelligence Techniques.
Kumar, Rajnish; Sharma, Anju; Siddiqui, Mohammed Haris; Tiwari, Rajesh Kumar
2017-01-01
Information about Pharmacokinetics of compounds is an essential component of drug design and development. Modeling the pharmacokinetic properties require identification of the factors effecting absorption, distribution, metabolism and excretion of compounds. There have been continuous attempts in the prediction of intestinal absorption of compounds using various Artificial intelligence methods in the effort to reduce the attrition rate of drug candidates entering to preclinical and clinical trials. Currently, there are large numbers of individual predictive models available for absorption using machine learning approaches. Six Artificial intelligence methods namely, Support vector machine, k- nearest neighbor, Probabilistic neural network, Artificial neural network, Partial least square and Linear discriminant analysis were used for prediction of absorption of compounds. Prediction accuracy of Support vector machine, k- nearest neighbor, Probabilistic neural network, Artificial neural network, Partial least square and Linear discriminant analysis for prediction of intestinal absorption of compounds was found to be 91.54%, 88.33%, 84.30%, 86.51%, 79.07% and 80.08% respectively. Comparative analysis of all the six prediction models suggested that Support vector machine with Radial basis function based kernel is comparatively better for binary classification of compounds using human intestinal absorption and may be useful at preliminary stages of drug design and development. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.
NASA Technical Reports Server (NTRS)
Hertzberg, A.; Decher, R.; Mattick, A. T.; Lau, C. V.
1978-01-01
High temperature heat engines designed to make maximum use of the thermodynamic potential of concentrated solar radiation are described. Plasmas between 2000 K and 4000 K can be achieved by volumetric absorption of radiation in alkali metal vapors, leading to thermal efficiencies up to 75% for terrestrial solar power plants and up to 50% for space power plants. Two machines capable of expanding hot plasmas using practical technology are discussed. A binary Rankine cycle uses fluid mechanical energy transfer in a device known as the 'Comprex' or 'energy exchanger.' The second machine utilizes magnetohydrodynamics in a Brayton cycle for space applications. Absorption of solar energy and plasma radiation losses are investigated for a solar superheater using potassium vapor.
Prediction of the far field noise from wind energy farms
NASA Technical Reports Server (NTRS)
Shepherd, K. P.; Hubbard, H. H.
1986-01-01
The basic physical factors involved in making predictions of wind turbine noise and an approach which allows for differences in the machines, the wind energy farm configurations and propagation conditions are reviewed. Example calculations to illustrate the sensitivity of the radiated noise to such variables as machine size, spacing and numbers, and such atmosphere variables as absorption and wind direction are presented. It is found that calculated far field distances to particular sound level contours are greater for lower values of atmospheric absorption, for a larger total number of machines, for additional rows of machines and for more powerful machines. At short and intermediate distances, higher sound pressure levels are calculated for closer machine spacings, for more powerful machines, for longer row lengths and for closer row spacings.
NASA Astrophysics Data System (ADS)
Kislyakov, M. A.; Chernov, V. A.; Maksimkin, V. L.; Bozhin, Yu. M.
2017-12-01
The article deals with modern methods of monitoring the state and predicting the life of electric machines. In 50% of the cases of failure in the performance of electric machines is associated with insulation damage. As promising, nondestructive methods of control, methods based on the investigation of the processes of polarization occurring in insulating materials are proposed. To improve the accuracy of determining the state of insulation, a multiparametric approach is considered, which is a basis for the development of an expert system for estimating the state of health.
Direct fired absorption machine flue gas recuperator
Reimann, Robert C.; Root, Richard A.
1985-01-01
A recuperator which recovers heat from a gas, generally the combustion gas of a direct-fired generator of an absorption machine. The recuperator includes a housing with liquid flowing therethrough, the liquid being in direct contact with the combustion gas for increasing the effectiveness of the heat transfer between the gas and the liquid.
Simulation model of a single-stage lithium bromide-water absorption cooling unit
NASA Technical Reports Server (NTRS)
Miao, D.
1978-01-01
A computer model of a LiBr-H2O single-stage absorption machine was developed. The model, utilizing a given set of design data such as water-flow rates and inlet or outlet temperatures of these flow rates but without knowing the interior characteristics of the machine (heat transfer rates and surface areas), can be used to predict or simulate off-design performance. Results from 130 off-design cases for a given commercial machine agree with the published data within 2 percent.
Improvement of the COP of the LiBr-Water Double-Effect Absorption Cycles
NASA Astrophysics Data System (ADS)
Shitara, Atsushi
Prevention of the global warming has called for a great necessity for energy saving. This applies to the improvement of the COP of absorption chiller-heaters. We started the development of the high efficiency gas-fired double-effect absorption chiller-heater using LiBr-H2O to achieve target performance in short or middle term. To maintain marketability, the volume of the high efficiency machine has been set below the equal to the conventional machine. The absorption cycle technology for improving the COP and the element technology for downsizing the machine is necessary in this development. In this study, the former is investigated. In this report, first of all the target performance has been set at cooling COP of 1.35(on HHV), which is 0.35 higher than the COP of 1.0 for conventional machines in the market. This COP of 1.35 is practically close to the maximum limit achievable by double-effect absorption chiller-heater. Next, the design condition of each element to achieve the target performance and the effect of each mean to improve the COP are investigated. Moreover, as a result of comparing the various flows(series, parallel, reverse)to which the each mean is applied, it has been found the optimum cycle is the parallel flow.
A Broadband Micro-Machined Far-Infrared Absorber
NASA Technical Reports Server (NTRS)
Wollack, E. J.; Datesman, A. M.; Jhabvala, C. A.; Miller, K. H.; Quijada, M. A.
2016-01-01
The experimental investigation of a broadband far-infrared meta-material absorber is described. The observed absorptance is greater than 0.95 from 1 to 20 terahertz (300-15 microns) over a temperature range spanning 5-300 degrees Kelvin. The meta-material, realized from an array of tapers approximately 100 microns in length, is largely insensitive to the detailed geometry of these elements and is cryogenically compatible with silicon-based micro-machined technologies. The electromagnetic response is in general agreement with a physically motivated transmission line model.
Mewes, D; Trapp, R P
2000-01-01
Guards on machine tools are meant to protect operators from injuries caused by tools, workpieces, and fragments hurled out of the machine's working zone. This article presents the impact resistance requirements, which guards according to European safety standards for machine tools must satisfy. Based upon these standards the impact resistance of different guard materials was determined using cylindrical steel projectiles. Polycarbonate proves to be a suitable material for vision panels because of its high energy absorption capacity. The impact resistance of 8-mm thick polycarbonate is roughly equal to that of a 3-mm thick steel sheet Fe P01. The limited ageing stability, however, makes it necessary to protect polycarbonate against cooling lubricants by means of additional panes on both sides.
NASA Astrophysics Data System (ADS)
Sharif, Hafiz Zafar; Leman, A. M.; Muthuraman, S.; Salleh, Mohd Najib Mohd; Zakaria, Supaat
2017-09-01
Combined heating, cooling, and power is also known as Tri-generation. Tri-generation system can provide power, hot water, space heating and air -conditioning from single source of energy. The objective of this study is to propose a method to evaluate the characteristic and performance of a single stage lithium bromide-water (LiBr-H2O) absorption machine operated with waste thermal energy of internal combustion engine which is integral part of trigeneration system. Correlations for computer sensitivity analysis are developed in data fit software for (P-T-X), (H-T-X), saturated liquid (water), saturated vapor, saturation pressure and crystallization temperature curve of LiBr-H2O Solution. Number of equations were developed with data fit software and exported into excel work sheet for the evaluation of number of parameter concerned with the performance of vapor absorption machine such as co-efficient of performance, concentration of solution, mass flow rate, size of heat exchangers of the unit in relation to the generator, condenser, absorber and evaporator temperatures. Size of vapor absorption machine within its crystallization limits for cooling and heating by waste energy recovered from exhaust gas, and jacket water of internal combustion engine also presented in this study to save the time and cost for the facilities managers who are interested to utilize the waste thermal energy of their buildings or premises for heating and air conditioning applications.
NASA Astrophysics Data System (ADS)
Daido, Hiroyuki; Abe, Hiroshi; Shobu, Takahisa; Shimomura, Takuya; Tokuhira, Shinnosuke; Takenaka, Yusuke; Furuyama, Takehiro; Nishimura, Akihiko; Uchida, Hirohisa; Ohshima, Takeshi
2015-09-01
Hydrogen storage alloys become more and more important in the fields of electric energy production and stage and automobiles such as Ni-MH batteries. The vacancies introduced in hydrogen absorption alloy by charged particle beams were found to be positive effect on the increase in the initial hydrogen absorption reaction rate in the previous study. The initial reaction rates of hydrogen absorption and desorption of the alloy are one of the important performances to be improved. Here, we report on the characterization of the hydrogen absorption reaction rate directly illuminated by a femtosecond and nanosecond lasers instead of particle beam machines. A laser illuminates the whole surface sequentially on a tip of a few cm square LaNi4.6Al0.4 alloy resulting in significant improvement in the hydrogen absorption reaction rate. For characterization of the surface layer, we perform an x-ray diffraction experiment using a monochromatized intense x-ray beam from SPring-8 synchrotoron machine.
Promises of Machine Learning Approaches in Prediction of Absorption of Compounds.
Kumar, Rajnish; Sharma, Anju; Siddiqui, Mohammed Haris; Tiwari, Rajesh Kumar
2018-01-01
The Machine Learning (ML) is one of the fastest developing techniques in the prediction and evaluation of important pharmacokinetic properties such as absorption, distribution, metabolism and excretion. The availability of a large number of robust validation techniques for prediction models devoted to pharmacokinetics has significantly enhanced the trust and authenticity in ML approaches. There is a series of prediction models generated and used for rapid screening of compounds on the basis of absorption in last one decade. Prediction of absorption of compounds using ML models has great potential across the pharmaceutical industry as a non-animal alternative to predict absorption. However, these prediction models still have to go far ahead to develop the confidence similar to conventional experimental methods for estimation of drug absorption. Some of the general concerns are selection of appropriate ML methods and validation techniques in addition to selecting relevant descriptors and authentic data sets for the generation of prediction models. The current review explores published models of ML for the prediction of absorption using physicochemical properties as descriptors and their important conclusions. In addition, some critical challenges in acceptance of ML models for absorption are also discussed. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.
Absorption machine with desorber-resorber
Biermann, Wendell J.
1985-01-01
An absorption refrigeration system utilizing a low temperature desorber and intermediate temperature resorber. The system operates at three temperatures and three pressures to increase the efficiency of the system and is capable of utilizing a lower generator temperature than previously used.
Deep Learning Accurately Predicts Estrogen Receptor Status in Breast Cancer Metabolomics Data.
Alakwaa, Fadhl M; Chaudhary, Kumardeep; Garmire, Lana X
2018-01-05
Metabolomics holds the promise as a new technology to diagnose highly heterogeneous diseases. Conventionally, metabolomics data analysis for diagnosis is done using various statistical and machine learning based classification methods. However, it remains unknown if deep neural network, a class of increasingly popular machine learning methods, is suitable to classify metabolomics data. Here we use a cohort of 271 breast cancer tissues, 204 positive estrogen receptor (ER+), and 67 negative estrogen receptor (ER-) to test the accuracies of feed-forward networks, a deep learning (DL) framework, as well as six widely used machine learning models, namely random forest (RF), support vector machines (SVM), recursive partitioning and regression trees (RPART), linear discriminant analysis (LDA), prediction analysis for microarrays (PAM), and generalized boosted models (GBM). DL framework has the highest area under the curve (AUC) of 0.93 in classifying ER+/ER- patients, compared to the other six machine learning algorithms. Furthermore, the biological interpretation of the first hidden layer reveals eight commonly enriched significant metabolomics pathways (adjusted P-value <0.05) that cannot be discovered by other machine learning methods. Among them, protein digestion and absorption and ATP-binding cassette (ABC) transporters pathways are also confirmed in integrated analysis between metabolomics and gene expression data in these samples. In summary, deep learning method shows advantages for metabolomics based breast cancer ER status classification, with both the highest prediction accuracy (AUC = 0.93) and better revelation of disease biology. We encourage the adoption of feed-forward networks based deep learning method in the metabolomics research community for classification.
Thermal-mechanical modeling of laser ablation hybrid machining
NASA Astrophysics Data System (ADS)
Matin, Mohammad Kaiser
2001-08-01
Hard, brittle and wear-resistant materials like ceramics pose a problem when being machined using conventional machining processes. Machining ceramics even with a diamond cutting tool is very difficult and costly. Near net-shape processes, like laser evaporation, produce micro-cracks that require extra finishing. Thus it is anticipated that ceramic machining will have to continue to be explored with new-sprung techniques before ceramic materials become commonplace. This numerical investigation results from the numerical simulations of the thermal and mechanical modeling of simultaneous material removal from hard-to-machine materials using both laser ablation and conventional tool cutting utilizing the finite element method. The model is formulated using a two dimensional, planar, computational domain. The process simulation acronymed, LAHM (Laser Ablation Hybrid Machining), uses laser energy for two purposes. The first purpose is to remove the material by ablation. The second purpose is to heat the unremoved material that lies below the ablated material in order to ``soften'' it. The softened material is then simultaneously removed by conventional machining processes. The complete solution determines the temperature distribution and stress contours within the material and tracks the moving boundary that occurs due to material ablation. The temperature distribution is used to determine the distance below the phase change surface where sufficient ``softening'' has occurred, so that a cutting tool may be used to remove additional material. The model incorporated for tracking the ablative surface does not assume an isothermal melt phase (e.g. Stefan problem) for laser ablation. Both surface absorption and volume absorption of laser energy as function of depth have been considered in the models. LAHM, from the thermal and mechanical point of view is a complex machining process involving large deformations at high strain rates, thermal effects of the laser, removal of materials and contact between workpiece and tool. The theoretical formulation associated with LAHM for solving the thermal-mechanical problem using the finite element method is presented. The thermal formulation is incorporated in the user defined subroutines called by ABAQUS/Standard. The mechanical portion is modeled using ABAQUS/Explicit's general capabilities of modeling interactions involving contact and separation. The results obtained from the FEA simulations showed that the cutting force decrease considerably in both LAEM Surface Absorption (LARM-SA) and LAHM volume absorption (LAHM-VA) models relative to LAM model. It was observed that the HAZ can be expanded or narrowed depending on the laser speed and power. The cutting force is minimal at the last extent of the HAZ. In both the models the laser ablates material thus reducing material stiffness as well as relaxing the thermal stress. The stress values obtained showed compressive yield stress just below the ablated surface and chip. The failure occurs by conventional cutting where tensile stress exceeds the tensile strength of the material at that temperature. In this hybrid machining process the advantages of both the individual machining processes were realized.
TEA CO2 laser machining of CFRP composite
NASA Astrophysics Data System (ADS)
Salama, A.; Li, L.; Mativenga, P.; Whitehead, D.
2016-05-01
Carbon fibre-reinforced polymer (CFRP) composites have found wide applications in the aerospace, marine, sports and automotive industries owing to their lightweight and acceptable mechanical properties compared to the commonly used metallic materials. Machining of CFRP composites using lasers can be challenging due to inhomogeneity in the material properties and structures, which can lead to thermal damages during laser processing. In the previous studies, Nd:YAG, diode-pumped solid-state, CO2 (continuous wave), disc and fibre lasers were used in cutting CFRP composites and the control of damages such as the size of heat-affected zones (HAZs) remains a challenge. In this paper, a short-pulsed (8 μs) transversely excited atmospheric pressure CO2 laser was used, for the first time, to machine CFRP composites. The laser has high peak powers (up to 250 kW) and excellent absorption by both the carbon fibre and the epoxy binder. Design of experiment and statistical modelling, based on response surface methodology, was used to understand the interactions between the process parameters such as laser fluence, repetition rate and cutting speed and their effects on the cut quality characteristics including size of HAZ, machining depth and material removal rate (MRR). Based on this study, process parameter optimization was carried out to minimize the HAZ and maximize the MRR. A discussion is given on the potential applications and comparisons to other lasers in machining CFRP.
Evaluation and selection of refrigeration systems for lunar surface and space applications
NASA Technical Reports Server (NTRS)
Copeland, R. J.; Blount, T. D.; Williams, J. L.
1971-01-01
Evaluated are the various refrigeration machines which could be used to provide heat rejection in environmental control systems for lunar surface and spacecraft applications, in order to select the best refrigeration machine for satisfying each individual application and the best refrigeration machine for satisfying all of the applications. The refrigeration machine considered include: (1) vapor comparison cycle (work-driven); (2) vapor adsorption cycle (heat-driven); (3) vapor absorption cycle (heat-driven); (4) thermoelectric (electrically-driven); (5) gas cycle (work driven); (6) steam-jet (heat-driven).
Werblinski, Thomas; Fendt, Peter; Zigan, Lars; Will, Stefan
2017-05-20
The first results under fired internal combustion engine conditions based on a supercontinuum absorption spectrometer are presented and discussed. Temperature, pressure, and water mole fraction are inferred simultaneously from broadband H 2 O absorbance spectra ranging from 1340 nm to 1440 nm. The auto-ignition combustion process is monitored for two premixed n-heptane/air mixtures with 10 kHz in a rapid compression machine. Pressure and temperature levels during combustion exceed 65 bar and 1900 K, respectively. To allow for combustion measurements, the robustness of the spectrometer against beam steering has been improved compared to its previous version. Additionally, the detectable wavelength range has been extended further into the infrared region to allow for the acquisition of distinct high-temperature water transitions located in the P-branch above 1410 nm. Based on a theoretical study, line-of-sight (LOS) effects introduced by temperature stratification on the broadband fitting algorithm in the complete range from 1340 nm to 1440 nm are discussed. In this context, the recorded spectra during combustion were evaluated only within a narrower spectral region exhibiting almost no interference from low-temperature molecules (here, P-branch from 1410 nm to 1440 nm). It is shown that this strategy mitigates almost all of the LOS effects introduced by cold molecules and the evaluation of the spectrum in the entirely recorded wavelength range at engine combustion conditions.
Nd:YAG Pulsed Laser Assisted Machining of AMS 5708 Waspaloy Alloy
NASA Astrophysics Data System (ADS)
Sharifi, Zahra; Shoja-Razavi, Reza; Vafaei, Reza; Hashemi, Sayed Hamid
2018-03-01
Due to very high strenght, low thermal conductivity, and high work hardening rate, the machinability of nickel-based superalloys is poor at room temperature. Laser-assisted machining (LAM) can provide a better aspect of machining such alloys. Since the wavelength of Nd:YAG laser is about 1/10th of that of CO2 laser, absorption and heating efficiency of Nd:YAG laser is much higher on metals and especially superalloys. Transmission of Nd:YAG laser through fiber optics to the heating point on the workpiece is a simple task during machining. This makes the LAM process more convenient and practical than the CM process. In this study a model is introduced for LAM of waspaloy, and its machinability is evaluated in terms of ease of material removal. Also, a temperature generation model is introduced for the Nd:YAG laser beam. Furthemore, wear behavior of an uncoated tungsten carbide and the formed chips were compared during the LAM and the CM of waspolay. To study the wear mechanism, the worn cutting tool was studied via scanning electron microscopy (SEM) and energy dispersive x-ray spectroscopy (EDS). The formed chips were also evaluated via SEM and optical microscopy. Based on the results, the optimum LAM conditions were obtained at a cutting speed of 24 m/min and a feed rate of 0.06 mm/rev when a 400 W laser mean power and 80 Hz frequency are applied. Under these conditions, the temperature ahead of the cutting tool edge on the surface of workpiece was estimated to be 524°C. In comparison with CM, a significant improvement in tool wear and a better chip morphology were achieved through LAM, and also specific cutting energy and surface roughness were reduced by 25 and 20%, respectively.
Tomita, Takashi; Tsukimura, Naoki; Ohno, Shigeru; Umekawa, Yoshitada; Sawano, Muneyuki; Fujimoto, Toshiki; Takamura, Masaaki; Majima, Aiko; Katakura, Yuusuke; Kurata, Akemi; Ohyama, Tetsuo; Ishigami, Tomohiko
2006-04-01
To consider changes in the physical properties of mouthguard materials with the change of temperature, shock-absorbing examination and Shore hardness measurement of existing MG materials and other elastic materials were carried out. Both examinations were done under two temperature conditions: at room temperature (25 degrees C) and simulated intraoral temperature (37 degrees C). In addition, a comparative study of the relation between Shore hardness and shock absorption of the materials was made. A self-made drop impact machine was used for the shock-absorbing examination. The thickness of a sample was assumed to be 3 mm. The loading was applied by dropping 3 kinds of steel ball, phi 10 mm (4.0 g), phi 15 mm (13.7 g), and phi 20 mm (32.6 g) from a height of 60 cm. The shock absorption of all materials was compared by the maximum impact force. Shore hardness was measured based on the JIS standard. The shock absorption of each material showed a different tendency depending on the loading condition. Furthermore, the shock absorption of the same material showed different results depending on the temperature condition. Shore hardness measurements tended to show low values with the condition of 37 degrees C for all materials. From the relation between shock absorption and Shore hardness, it was confirmed that there is a correlation between hardness and the maximum impact force in the materials that showed shock absorption by elastic deformation. Some materials showed high shock absorption compared with existing MG materials.
NASA Astrophysics Data System (ADS)
Bauke, Stephan; Golibrzuch, Kai; Wackerbarth, Hainer; Fendt, Peter; Zigan, Lars; Seefeldt, Stefan; Thiele, Olaf; Berg, Thomas
2018-05-01
Lowering greenhouse gas emissions is one of the most challenging demands of today's society. Especially, the automotive industry struggles with the development of more efficient internal combustion (IC) engines. As an alternative to conventional fuels, methane has the potential for a significant emission reduction. In methane fuelled engines, the process of mixture formation, which determines the properties of combustion after ignition, differs significantly from gasoline and diesel engines and needs to be understood and controlled in order to develop engines with high efficiency. This work demonstrates the development of a gas sensing system that can serve as a diagnostic tool for measuring crank-angle resolved relative air-fuel ratios in methane-fuelled near-production IC engines. By application of non-dispersive infrared absorption spectroscopy at two distinct spectral regions in the ν3 absorption band of methane around 3.3 μm, the system is able to determine fuel density and temperature simultaneously. A modified spark plug probe allows for straightforward application at engine test stations. Here, the application of the detection system in a rapid compression machine is presented, which enables validation and characterization of the system on well-defined gas mixtures under engine-like dynamic conditions. In extension to a recent proof-of-principle study, a refined data analysis procedure is introduced that allows the correction of artefacts originating from mechanical distortions of the sensor probe. In addition, the measured temperatures are compared to data obtained with a commercially available system based on the spectrally resolved detection of water absorption in the near infrared.
Computational assessment of organic photovoltaic candidate compounds
NASA Astrophysics Data System (ADS)
Borunda, Mario; Dai, Shuo; Olivares-Amaya, Roberto; Amador-Bedolla, Carlos; Aspuru-Guzik, Alan
2015-03-01
Organic photovoltaic (OPV) cells are emerging as a possible renewable alternative to petroleum based resources and are needed to meet our growing demand for energy. Although not as efficient as silicon based cells, OPV cells have as an advantage that their manufacturing cost is potentially lower. The Harvard Clean Energy Project, using a cheminformatic approach of pattern recognition and machine learning strategies, has ranked a molecular library of more than 2.6 million candidate compounds based on their performance as possible OPV materials. Here, we present a ranking of the top 1000 molecules for use as photovoltaic materials based on their optical absorption properties obtained via time-dependent density functional theory. This computational search has revealed the molecular motifs shared by the set of most promising molecules.
Laser absorption of carbon fiber reinforced polymer with randomly distributed carbon fibers
NASA Astrophysics Data System (ADS)
Hu, Jun; Xu, Hebing; Li, Chao
2018-03-01
Laser processing of carbon fiber reinforced polymer (CFRP) is a non-traditional machining method which has many prospective applications. The laser absorption characteristics of CFRP are analyzed in this paper. A ray tracing model describing the interaction of the laser spot with CFRP is established. The material model contains randomly distributed carbon fibers which are generated using an improved carbon fiber placement method. It was found that CFRP has good laser absorption due to multiple reflections of the light rays in the material’s microstructure. The randomly distributed carbon fibers make the absorptivity of the light rays change randomly in the laser spot. Meanwhile, the average absorptivity fluctuation is obvious during movement of the laser. The experimental measurements agree well with the values predicted by the ray tracing model.
Precision machining of pig intestine using ultrafast laser pulses
NASA Astrophysics Data System (ADS)
Beck, Rainer J.; Góra, Wojciech S.; Carter, Richard M.; Gunadi, Sonny; Jayne, David; Hand, Duncan P.; Shephard, Jonathan D.
2015-07-01
Endoluminal surgery for the treatment of early stage colorectal cancer is typically based on electrocautery tools which imply restrictions on precision and the risk of harm through collateral thermal damage to the healthy tissue. As a potential alternative to mitigate these drawbacks we present laser machining of pig intestine by means of picosecond laser pulses. The high intensities of an ultrafast laser enable nonlinear absorption processes and a predominantly nonthermal ablation regime. Laser ablation results of square cavities with comparable thickness to early stage colorectal cancers are presented for a wavelength of 1030 nm using an industrial picosecond laser. The corresponding histology sections exhibit only minimal collateral damage to the surrounding tissue. The depth of the ablation can be controlled precisely by means of the pulse energy. Overall, the application of ultrafast lasers to ablate pig intestine enables significantly improved precision and reduced thermal damage to the surrounding tissue compared to conventional techniques.
Pelamis: experience from concept to connection.
Yemm, Richard; Pizer, David; Retzler, Chris; Henderson, Ross
2012-01-28
The development of the Pelamis wave energy converter from its conceptual origins to its commercial deployment is reviewed. The early emphasis on designing for survivability and favourable power absorption characteristics focused attention towards a self-referenced articulated line-absorber in an attenuator orientation. A novel joint and control system allow the machine to be actively tuned to provide a resonant response power amplification in small and moderate seas. In severe seas, the machine is left in its default or natural condition, which is benign and non-resonant. Hydraulic rams at the joints provide the primary power take-off with medium-term storage in high-pressure accumulators yielding smooth electricity generation. Land-based modular construction requiring minimal weather windows for rapid offshore installation is an essential engineering feature necessary for viable commercialization. The second-generation Pelamis designs built for E.ON and ScottishPower Renewables are presented, and the scope for further cost reduction and performance enhancements are explained.
Predicting ozone profile shape from satellite UV spectra
NASA Astrophysics Data System (ADS)
Xu, Jian; Loyola, Diego; Romahn, Fabian; Doicu, Adrian
2017-04-01
Identifying ozone profile shape is a critical yet challenging job for the accurate reconstruction of vertical distributions of atmospheric ozone that is relevant to climate change and air quality. Motivated by the need to develop an approach to reliably and efficiently estimate vertical information of ozone and inspired by the success of machine learning techniques, this work proposes a new algorithm for deriving ozone profile shapes from ultraviolet (UV) absorption spectra that are recorded by satellite instruments, e.g. GOME series and the future Sentinel missions. The proposed algorithm formulates this particular inverse problem in a classification framework rather than a conventional inversion one and places an emphasis on effectively characterizing various profile shapes based on machine learning techniques. Furthermore, a comparison of the ozone profiles from real GOME-2 data estimated by our algorithm and the classical retrieval algorithm (Optimal Estimation Method) is performed.
Nonequilibrium quantum absorption refrigerator
NASA Astrophysics Data System (ADS)
Du, Jian-Ying; Zhang, Fu-Lin
2018-06-01
We study a quantum absorption refrigerator, in which a target qubit is cooled by two machine qubits in a nonequilibrium steady-state. It is realized by a strong internal coupling in the two-qubit fridge and a vanishing tripartite interaction among the whole system. The coherence of a machine virtual qubit is investigated as quantumness of the fridge. A necessary condition for cooling shows that the quantum coherence is beneficial to the nonequilibrium fridge, while it is detrimental as far as the maximum coefficient of performance (COP) and the COP at maximum power are concerned. Here, the COP is defined only in terms of heat currents caused by the tripartite interaction, with the one maintaining the two-qubit nonequilibrium state being excluded. The later can be considered to have no direct involvement in extracting heat from the target, as it is not affected by the tripartite interaction.
NASA Astrophysics Data System (ADS)
Bukreeva, Ekaterina B.; Bulanova, Anna A.; Kistenev, Yury V.; Kuzmin, Dmitry A.; Tuzikov, Sergei A.; Yumov, Evgeny L.
2014-11-01
The results of the joint use of laser photoacoustic spectroscopy and chemometrics methods in gas analysis of exhaled air of patients with respiratory diseases (chronic obstructive pulmonary disease, pneumonia and lung cancer) are presented. The absorption spectra of exhaled breath of all volunteers were measured, the classification methods of the scans of the absorption spectra were applied, the sensitivity/specificity of the classification results were determined. It were obtained a result of nosological in pairs classification for all investigated volunteers, indices of sensitivity and specificity.
Korotcov, Alexandru; Tkachenko, Valery; Russo, Daniel P; Ekins, Sean
2017-12-04
Machine learning methods have been applied to many data sets in pharmaceutical research for several decades. The relative ease and availability of fingerprint type molecular descriptors paired with Bayesian methods resulted in the widespread use of this approach for a diverse array of end points relevant to drug discovery. Deep learning is the latest machine learning algorithm attracting attention for many of pharmaceutical applications from docking to virtual screening. Deep learning is based on an artificial neural network with multiple hidden layers and has found considerable traction for many artificial intelligence applications. We have previously suggested the need for a comparison of different machine learning methods with deep learning across an array of varying data sets that is applicable to pharmaceutical research. End points relevant to pharmaceutical research include absorption, distribution, metabolism, excretion, and toxicity (ADME/Tox) properties, as well as activity against pathogens and drug discovery data sets. In this study, we have used data sets for solubility, probe-likeness, hERG, KCNQ1, bubonic plague, Chagas, tuberculosis, and malaria to compare different machine learning methods using FCFP6 fingerprints. These data sets represent whole cell screens, individual proteins, physicochemical properties as well as a data set with a complex end point. Our aim was to assess whether deep learning offered any improvement in testing when assessed using an array of metrics including AUC, F1 score, Cohen's kappa, Matthews correlation coefficient and others. Based on ranked normalized scores for the metrics or data sets Deep Neural Networks (DNN) ranked higher than SVM, which in turn was ranked higher than all the other machine learning methods. Visualizing these properties for training and test sets using radar type plots indicates when models are inferior or perhaps over trained. These results also suggest the need for assessing deep learning further using multiple metrics with much larger scale comparisons, prospective testing as well as assessment of different fingerprints and DNN architectures beyond those used.
Responsive materials: A novel design for enhanced machine-augmented composites
Bafekrpour, Ehsan; Molotnikov, Andrey; Weaver, James C.; Brechet, Yves; Estrin, Yuri
2014-01-01
The concept of novel responsive materials with a displacement conversion capability was further developed through the design of new machine-augmented composites (MACs). Embedded converter machines and MACs with improved geometry were designed and fabricated by multi-material 3D printing. This technique proved to be very effective in fabricating these novel composites with tuneable elastic moduli of the matrix and the embedded machines and excellent bonding between them. Substantial improvement in the displacement conversion efficiency of the new MACs over the existing ones was demonstrated. Also, the new design trebled the energy absorption of the MACs. Applications in energy absorbers as well as mechanical sensors and actuators are thus envisaged. A further type of MACs with conversion ability, viz. conversion of compressive displacements to torsional ones, was also proposed. PMID:24445490
Quantum-enhanced absorption refrigerators
Correa, Luis A.; Palao, José P.; Alonso, Daniel; Adesso, Gerardo
2014-01-01
Thermodynamics is a branch of science blessed by an unparalleled combination of generality of scope and formal simplicity. Based on few natural assumptions together with the four laws, it sets the boundaries between possible and impossible in macroscopic aggregates of matter. This triggered groundbreaking achievements in physics, chemistry and engineering over the last two centuries. Close analogues of those fundamental laws are now being established at the level of individual quantum systems, thus placing limits on the operation of quantum-mechanical devices. Here we study quantum absorption refrigerators, which are driven by heat rather than external work. We establish thermodynamic performance bounds for these machines and investigate their quantum origin. We also show how those bounds may be pushed beyond what is classically achievable, by suitably tailoring the environmental fluctuations via quantum reservoir engineering techniques. Such superefficient quantum-enhanced cooling realises a promising step towards the technological exploitation of autonomous quantum refrigerators. PMID:24492860
Simulation of a 20-ton LiBr/H{sub 2}O absorption cooling system
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wardono, B.; Nelson, R.M.
The possibility of using solar energy as the main heat input for cooling systems has led to several studies of available cooling technologies that use solar energy. The results show that double-effect absorption cooling systems give relatively high performance. To further study absorption cooling systems, a computer code was developed for a double-effect lithium bromide/water (LiBr/H{sub 2}O) absorption system. To evaluate the performance, two objective functions were developed including the coefficient of performance (COP) and the system cost. Based on the system cost, an optimization to find the minimum cost was performed to determine the nominal heat transfer areas ofmore » each heat exchanger. The nominal values of other system variables, such as the mass flow rates and inlet temperatures of the hot water, cooling water, and chilled water, are specified as commonly used values for commercial machines. The results of the optimization show that there are optimum heat transfer areas. In this study, hot water is used as the main energy input. Using a constant load of 20 tons cooling capacity, the effects of various variables including the heat transfer ares, mass flow rates, and inlet temperatures of hot water, cooling water, and chilled water are presented.« less
Rapid tomographic reconstruction based on machine learning for time-resolved combustion diagnostics
NASA Astrophysics Data System (ADS)
Yu, Tao; Cai, Weiwei; Liu, Yingzheng
2018-04-01
Optical tomography has attracted surged research efforts recently due to the progress in both the imaging concepts and the sensor and laser technologies. The high spatial and temporal resolutions achievable by these methods provide unprecedented opportunity for diagnosis of complicated turbulent combustion. However, due to the high data throughput and the inefficiency of the prevailing iterative methods, the tomographic reconstructions which are typically conducted off-line are computationally formidable. In this work, we propose an efficient inversion method based on a machine learning algorithm, which can extract useful information from the previous reconstructions and build efficient neural networks to serve as a surrogate model to rapidly predict the reconstructions. Extreme learning machine is cited here as an example for demonstrative purpose simply due to its ease of implementation, fast learning speed, and good generalization performance. Extensive numerical studies were performed, and the results show that the new method can dramatically reduce the computational time compared with the classical iterative methods. This technique is expected to be an alternative to existing methods when sufficient training data are available. Although this work is discussed under the context of tomographic absorption spectroscopy, we expect it to be useful also to other high speed tomographic modalities such as volumetric laser-induced fluorescence and tomographic laser-induced incandescence which have been demonstrated for combustion diagnostics.
Rapid tomographic reconstruction based on machine learning for time-resolved combustion diagnostics.
Yu, Tao; Cai, Weiwei; Liu, Yingzheng
2018-04-01
Optical tomography has attracted surged research efforts recently due to the progress in both the imaging concepts and the sensor and laser technologies. The high spatial and temporal resolutions achievable by these methods provide unprecedented opportunity for diagnosis of complicated turbulent combustion. However, due to the high data throughput and the inefficiency of the prevailing iterative methods, the tomographic reconstructions which are typically conducted off-line are computationally formidable. In this work, we propose an efficient inversion method based on a machine learning algorithm, which can extract useful information from the previous reconstructions and build efficient neural networks to serve as a surrogate model to rapidly predict the reconstructions. Extreme learning machine is cited here as an example for demonstrative purpose simply due to its ease of implementation, fast learning speed, and good generalization performance. Extensive numerical studies were performed, and the results show that the new method can dramatically reduce the computational time compared with the classical iterative methods. This technique is expected to be an alternative to existing methods when sufficient training data are available. Although this work is discussed under the context of tomographic absorption spectroscopy, we expect it to be useful also to other high speed tomographic modalities such as volumetric laser-induced fluorescence and tomographic laser-induced incandescence which have been demonstrated for combustion diagnostics.
National Synchrotron Light Source annual report 1991
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hulbert, S.L.; Lazarz, N.M.
1992-04-01
This report discusses the following research conducted at NSLS: atomic and molecular science; energy dispersive diffraction; lithography, microscopy and tomography; nuclear physics; UV photoemission and surface science; x-ray absorption spectroscopy; x-ray scattering and crystallography; x-ray topography; workshop on surface structure; workshop on electronic and chemical phenomena at surfaces; workshop on imaging; UV FEL machine reviews; VUV machine operations; VUV beamline operations; VUV storage ring parameters; x-ray machine operations; x-ray beamline operations; x-ray storage ring parameters; superconducting x-ray lithography source; SXLS storage ring parameters; the accelerator test facility; proposed UV-FEL user facility at the NSLS; global orbit feedback systems; and NSLSmore » computer system.« less
Panel Board From Coconut Fibre And Pet Bottle
NASA Astrophysics Data System (ADS)
Ngadiman, Norhayati; Kaamin, Masiri; Abd. Kadir, Aslila; Sahat, Suhaila; Zaini, Aziza; Raihana Nor Zentan, Siti; Ain Ahmad, Nur; Amran, Wan Haizatul Aisyhah Wan
2018-03-01
The rate of global deforestation and its impact on the environment has led particle board manufacture to search for alternative feedstock, especially in countries where wood is less available compared to other cellulosic natural product. Based on the properties of coconut fibre and PET bottle, these two materials can be recycle as raw material for manufacture of panel board. As for this study, the coconut fibre were used as the filler and PET bottle as outer lining of the panel board. Two types of coconut fibre were used which are grinding and un-grinding coconut fibre. At first, the coconut fibre are undergoes softening, grinding, drying and sieving process, while PET bottle was cleaning, shredding, sieving before compacted using hydraulic hot press machine. There are four types of testing that been carried out which are swelling, water absorption, Modulus of Elasticity (MOE) and Modulus of Rupture (MOR). The result show the conventional board has the highest value for MOE test, so it's indicate that the conventional board is less strength from the coconut fibre board. As for water absorption test, the average water absorption of coconut fibre based panel board is less than conventional board. Overall, the coconut fibre board is better than conventional panel board because coconut fibre board are less swelling, has low water absorption, high modulus of rupture and low modulus of elasticity. Based on the finding, this coconut fibre panel board has potential as a stronger and long-lasting panel board than the conventional board in the market. Other than that, the panel also have their own aesthetic value since the recycled plastic bottle used as outer lining is colourful and giving aesthetic value.
NASA Astrophysics Data System (ADS)
Taroni, Paola; Paganoni, Anna Maria; Ieva, Francesca; Pifferi, Antonio; Quarto, Giovanna; Abbate, Francesca; Cassano, Enrico; Cubeddu, Rinaldo
2017-01-01
Several techniques are being investigated as a complement to screening mammography, to reduce its false-positive rate, but results are still insufficient to draw conclusions. This initial study explores time domain diffuse optical imaging as an adjunct method to classify non-invasively malignant vs benign breast lesions. We estimated differences in tissue composition (oxy- and deoxyhemoglobin, lipid, water, collagen) and absorption properties between lesion and average healthy tissue in the same breast applying a perturbative approach to optical images collected at 7 red-near infrared wavelengths (635-1060 nm) from subjects bearing breast lesions. The Discrete AdaBoost procedure, a machine-learning algorithm, was then exploited to classify lesions based on optically derived information (either tissue composition or absorption) and risk factors obtained from patient’s anamnesis (age, body mass index, familiarity, parity, use of oral contraceptives, and use of Tamoxifen). Collagen content, in particular, turned out to be the most important parameter for discrimination. Based on the initial results of this study the proposed method deserves further investigation.
[New method of mixed gas infrared spectrum analysis based on SVM].
Bai, Peng; Xie, Wen-Jun; Liu, Jun-Hua
2007-07-01
A new method of infrared spectrum analysis based on support vector machine (SVM) for mixture gas was proposed. The kernel function in SVM was used to map the seriously overlapping absorption spectrum into high-dimensional space, and after transformation, the high-dimensional data could be processed in the original space, so the regression calibration model was established, then the regression calibration model with was applied to analyze the concentration of component gas. Meanwhile it was proved that the regression calibration model with SVM also could be used for component recognition of mixture gas. The method was applied to the analysis of different data samples. Some factors such as scan interval, range of the wavelength, kernel function and penalty coefficient C that affect the model were discussed. Experimental results show that the component concentration maximal Mean AE is 0.132%, and the component recognition accuracy is higher than 94%. The problems of overlapping absorption spectrum, using the same method for qualitative and quantitative analysis, and limit number of training sample, were solved. The method could be used in other mixture gas infrared spectrum analyses, promising theoretic and application values.
NASA Astrophysics Data System (ADS)
Anheier, N. C., Jr.; McDonald, C. E.; Cuta, J. M.; Cuta, F. M.; Olsen, K. B.
1995-05-01
This report describes an evaluation of various sensing techniques for determining the ammonia concentration in the working fluid of ammonia/water absorption cycle systems. The purpose was to determine if any existing sensor technology or instrumentation could provide an accurate, reliable, and cost-effective continuous measure of ammonia concentration in water. The resulting information will be used for design optimization and cycle control in an ammonia-absorption heat pump. Pacific Northwest Laboratory (PNL) researchers evaluated each sensing technology against a set of general requirements characterizing the potential operating conditions within the absorption cycle. The criteria included the physical constraints for in situ operation, sensor characteristics, and sensor application. PNL performed an extensive literature search, which uncovered several promising sensing technologies that might be applicable to this problem. Sixty-two references were investigated, and 33 commercial vendors were identified as having ammonia sensors. The technologies for ammonia sensing are acoustic wave, refractive index, electrode, thermal, ion-selective field-effect transistor (ISFET), electrical conductivity, pH/colormetric, and optical absorption. Based on information acquired in the literature search, PNL recommends that follow-on activities focus on ISFET devices and a fiber optic evanescent sensor with a colormetric indicator. The ISFET and fiber optic evanescent sensor are inherently microminiature and capable of in situ measurements. Further, both techniques have been demonstrated selective to the ammonium ion (NH4(+)). The primary issue remaining is how to make the sensors sufficiently corrosion-resistant to be useful in practice.
Preatoni, Ezio; Stokes, Keith A; England, Michael E; Trewartha, Grant
2015-04-01
This cross-sectional study investigated the factors that may influence the physical loading on rugby forwards performing a scrum by studying the biomechanics of machine-based scrummaging under different engagement techniques and playing levels. 34 forward packs from six playing levels performed repetitions of five different types of engagement techniques against an instrumented scrum machine under realistic training conditions. Applied forces and body movements were recorded in three orthogonal directions. The modification of the engagement technique altered the load acting on players. These changes were in a similar direction and of similar magnitude irrespective of the playing level. Reducing the dynamics of the initial engagement through a fold-in procedure decreased the peak compression force, the peak downward force and the engagement speed in excess of 30%. For example, peak compression (horizontal) forces in the professional teams changed from 16.5 (baseline technique) to 8.6 kN (fold-in procedure). The fold-in technique also reduced the occurrence of combined high forces and head-trunk misalignment during the absorption of the impact, which was used as a measure of potential hazard, by more than 30%. Reducing the initial impact did not decrease the ability of the teams to produce sustained compression forces. De-emphasising the initial impact against the scrum machine decreased the mechanical stresses acting on forward players and may benefit players' welfare by reducing the hazard factors that may induce chronic degeneration of the spine. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.
Timoshenko, Janis; Lu, Deyu; Lin, Yuewei; ...
2017-09-29
Tracking the structure of heterogeneous catalysts under operando conditions remains a challenge due to the paucity of experimental techniques that can provide atomic-level information for catalytic metal species. Here we report on the use of X-ray absorption near edge structure (XANES) spectroscopy and supervised machine learning (SML) for refining the three-dimensional geometry of metal catalysts. SML is used to unravel the hidden relationship between the XANES features and catalyst geometry. To train our SML method, we rely on ab-initio XANES simulations. Our approach allows one to solve the structure of a metal catalyst from its experimental XANES, as demonstrated heremore » by reconstructing the average size, shape and morphology of well-defined platinum nanoparticles. This method is applicable to the determination of the nanoparticle structure in operando studies and can be generalized to other nanoscale systems. In conclusion, it also allows on-the-fly XANES analysis, and is a promising approach for high-throughput and time-dependent studies.« less
Thermal Investigation of Interaction between High-power CW-laser Radiation and a Water-jet
NASA Astrophysics Data System (ADS)
Brecher, Christian; Janssen, Henning; Eckert, Markus; Schmidt, Florian
The technology of a water guided laser beam has been industrially established for micro machining. Pulsed laser radiation is guided via a water jet (diameter: 25-250 μm) using total internal reflection. Due to the cylindrical jet shape the depth of field increases to above 50 mm, enabling parallel kerfs compared to conventional laser systems. However higher material thicknesses and macro geometries cannot be machined economically viable due to low average laser powers. Fraunhofer IPT has successfully combined a high-power continuous-wave (CW) fiber laser (6 kW) and water jet technology. The main challenge of guiding high-power laser radiation in water is the energy transferred to the jet by absorption, decreasing its stability. A model of laser water interaction in the water jet has been developed and validated experimentally. Based on the results an upscaling of system technology to 30 kW is discussed, enabling a high potential in cutting challenging materials at high qualities and high speeds.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Timoshenko, Janis; Lu, Deyu; Lin, Yuewei
Tracking the structure of heterogeneous catalysts under operando conditions remains a challenge due to the paucity of experimental techniques that can provide atomic-level information for catalytic metal species. Here we report on the use of X-ray absorption near edge structure (XANES) spectroscopy and supervised machine learning (SML) for refining the three-dimensional geometry of metal catalysts. SML is used to unravel the hidden relationship between the XANES features and catalyst geometry. To train our SML method, we rely on ab-initio XANES simulations. Our approach allows one to solve the structure of a metal catalyst from its experimental XANES, as demonstrated heremore » by reconstructing the average size, shape and morphology of well-defined platinum nanoparticles. This method is applicable to the determination of the nanoparticle structure in operando studies and can be generalized to other nanoscale systems. In conclusion, it also allows on-the-fly XANES analysis, and is a promising approach for high-throughput and time-dependent studies.« less
Absorption of language concepts in the machine mind
NASA Astrophysics Data System (ADS)
Kollár, Ján
2016-06-01
In our approach, the machine mind is the applicative dynamic system represented by its algorithmically evolvable internal language. By other words, the mind and the language of mind are synonyms. Coming out from Shaumyan's semiotic theory of languages, we present the representation of language concepts in the machine mind as a result of our experiment, to show non-redundancy of the language of mind. To provide useful restriction for further research, we also introduce the hypothesis of semantic saturation in Computer-Computer communication, which indicates that a set of machines is not self-evolvable. The goal of our research is to increase the abstraction of Human-Computer and Computer-Computer communication. If we want humans and machines comunicate as a parent with the child, using different symbols and media, we must find the language of mind commonly usable by both machines and humans. In our opinion, there exist a kind of calm language of thinking, which we try to propose for machines in this paper. We separate the layers of a machine mind, we present the structure of the evolved mind and we discuss the selected properties. We are concentrating on the representation of symbolized concepts in the mind, that are languages, not just grammars, since they have meaning.
National Synchrotron Light Source annual report 1991. Volume 1, October 1, 1990--September 30, 1991
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hulbert, S.L.; Lazarz, N.M.
1992-04-01
This report discusses the following research conducted at NSLS: atomic and molecular science; energy dispersive diffraction; lithography, microscopy and tomography; nuclear physics; UV photoemission and surface science; x-ray absorption spectroscopy; x-ray scattering and crystallography; x-ray topography; workshop on surface structure; workshop on electronic and chemical phenomena at surfaces; workshop on imaging; UV FEL machine reviews; VUV machine operations; VUV beamline operations; VUV storage ring parameters; x-ray machine operations; x-ray beamline operations; x-ray storage ring parameters; superconducting x-ray lithography source; SXLS storage ring parameters; the accelerator test facility; proposed UV-FEL user facility at the NSLS; global orbit feedback systems; and NSLSmore » computer system.« less
Underwater image enhancement through depth estimation based on random forest
NASA Astrophysics Data System (ADS)
Tai, Shen-Chuan; Tsai, Ting-Chou; Huang, Jyun-Han
2017-11-01
Light absorption and scattering in underwater environments can result in low-contrast images with a distinct color cast. This paper proposes a systematic framework for the enhancement of underwater images. Light transmission is estimated using the random forest algorithm. RGB values, luminance, color difference, blurriness, and the dark channel are treated as features in training and estimation. Transmission is calculated using an ensemble machine learning algorithm to deal with a variety of conditions encountered in underwater environments. A color compensation and contrast enhancement algorithm based on depth information was also developed with the aim of improving the visual quality of underwater images. Experimental results demonstrate that the proposed scheme outperforms existing methods with regard to subjective visual quality as well as objective measurements.
Analysis of the atmospheric upward radiation in low latitude area
NASA Astrophysics Data System (ADS)
Li, Haiying; Wu, Zhensen; Lin, Leke; Lu, Changsheng
2016-10-01
Remote sensing using THz wave has irreplaceable advantage comparing to the microwave and the infrared waves, and study on the THz remote sensing become more and more popular in recent years. The major applications of the remote sensing in THz wavelengths are the retrieval of the atmospheric parameters and the microphysical information of the ice cloud. The remote sensing of the atmosphere is based on the radiation of THz wave along the earth-space path of which the most significant part is the upward radiation of the atmosphere. The upward radiation of the atmosphere in sunny day in the low latitude area is computed and analyzed in this paper. The absorption of THz wave by the atmosphere is calculated using the formulations illustrated in the Recommendation ITU-R P.676 to save machine hour, the frequency range is then restricted below 1THz. The frequencies used for the retrieval of atmospheric parameters such as temperature and water content are usually a few hundred GHz, at the lower end of THz wavelengths, so this frequency range is sufficient. The radiation contribution of every atmospheric layer for typical frequencies such as absorption window frequencies and peak frequencies are analyzed. Results show that at frequencies which absorption is severe, information about lower atmosphere cannot reach the receiver onboard a satellite or other high platforms due to the strong absorption along the path.
Qubit absorption refrigerator at strong coupling
NASA Astrophysics Data System (ADS)
Mu, Anqi; Agarwalla, Bijay Kumar; Schaller, Gernot; Segal, Dvira
2017-12-01
We demonstrate that a quantum absorption refrigerator (QAR) can be realized from the smallest quantum system, a qubit, by coupling it in a non-additive (strong) manner to three heat baths. This function is un-attainable for the qubit model under the weak system-bath coupling limit, when the dissipation is additive. In an optimal design, the reservoirs are engineered and characterized by a single frequency component. We then obtain closed expressions for the cooling window and refrigeration efficiency, as well as bounds for the maximal cooling efficiency and the efficiency at maximal power. Our results agree with macroscopic designs and with three-level models for QARs, which are based on the weak system-bath coupling assumption. Beyond the optimal limit, we show with analytical calculations and numerical simulations that the cooling efficiency varies in a non-universal manner with model parameters. Our work demonstrates that strongly-coupled quantum machines can exhibit function that is un-attainable under the weak system-bath coupling assumption.
Predicting human liver microsomal stability with machine learning techniques.
Sakiyama, Yojiro; Yuki, Hitomi; Moriya, Takashi; Hattori, Kazunari; Suzuki, Misaki; Shimada, Kaoru; Honma, Teruki
2008-02-01
To ensure a continuing pipeline in pharmaceutical research, lead candidates must possess appropriate metabolic stability in the drug discovery process. In vitro ADMET (absorption, distribution, metabolism, elimination, and toxicity) screening provides us with useful information regarding the metabolic stability of compounds. However, before the synthesis stage, an efficient process is required in order to deal with the vast quantity of data from large compound libraries and high-throughput screening. Here we have derived a relationship between the chemical structure and its metabolic stability for a data set of in-house compounds by means of various in silico machine learning such as random forest, support vector machine (SVM), logistic regression, and recursive partitioning. For model building, 1952 proprietary compounds comprising two classes (stable/unstable) were used with 193 descriptors calculated by Molecular Operating Environment. The results using test compounds have demonstrated that all classifiers yielded satisfactory results (accuracy > 0.8, sensitivity > 0.9, specificity > 0.6, and precision > 0.8). Above all, classification by random forest as well as SVM yielded kappa values of approximately 0.7 in an independent validation set, slightly higher than other classification tools. These results suggest that nonlinear/ensemble-based classification methods might prove useful in the area of in silico ADME modeling.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Anheier, N.C. Jr.; McDonald, C.E.; Cuta, J.M.
1995-05-01
This report describes an evaluation of various sensing techniques for determining the ammonia concentration in the working fluid of ammonia/water absorption cycle systems. The purpose of this work was to determine if any existing sensor technology or instrumentation could provide an accurate, reliable, and cost-effective continuous measure of ammonia concentration in water. The resulting information will be used for design optimization and cycle control in an ammonia-absorption heat pump. PNL researchers evaluated each sensing technology against a set of general requirements characterizing the potential operating conditions within the absorption cycle. The criteria included the physical constraints for in situ operation,more » sensor characteristics, and sensor application. PNL performed an extensive literature search, which uncovered several promising sensing technologies that might be applicable to this problem. Sixty-two references were investigated, and 33 commercial vendors were identified as having ammonia sensors. The technologies for ammonia sensing are acoustic wave, refractive index, electrode, thermal, ion-selective field-effect transistor (ISFET), electrical conductivity, pH/colormetric, and optical absorption. Based on information acquired in the literature search, PNL recommends that follow-on activities focus on ISFET devices and a fiber optic evanescent sensor with a colormetric indicator. The ISFET and fiber optic evanescent sensor are inherently microminiature and capable of in situ measurements. Further, both techniques have been demonstrated selective to the ammonium ion (NH{sub 4}{sup +}). The primary issue remaining is how to make the sensors sufficiently corrosion-resistant to be useful in practice.« less
Reimann, Robert C.; Root, Richard A.
1986-01-01
A gas-to-liquid heat exchanger system which transfers heat from a gas, generally the combustion gas of a direct-fired generator of an absorption machine, to a liquid, generally an absorbent solution. The heat exchanger system is in a counterflow fluid arrangement which creates a more efficient heat transfer.
Zhang, Jiang; Wang, James Z; Yuan, Zhen; Sobel, Eric S; Jiang, Huabei
2011-01-01
This study presents a computer-aided classification method to distinguish osteoarthritis finger joints from healthy ones based on the functional images captured by x-ray guided diffuse optical tomography. Three imaging features, joint space width, optical absorption, and scattering coefficients, are employed to train a Least Squares Support Vector Machine (LS-SVM) classifier for osteoarthritis classification. The 10-fold validation results show that all osteoarthritis joints are clearly identified and all healthy joints are ruled out by the LS-SVM classifier. The best sensitivity, specificity, and overall accuracy of the classification by experienced technicians based on manual calculation of optical properties and visual examination of optical images are only 85%, 93%, and 90%, respectively. Therefore, our LS-SVM based computer-aided classification is a considerably improved method for osteoarthritis diagnosis.
Fabrication of a novel carbon nanotube & graphene based device for gas detection
NASA Astrophysics Data System (ADS)
Khosravi, Yusef; Abdi, Yaser; Arzi, Ezatollah
2018-06-01
We present a novel, simple method for gas detection using a nano-device fabricated on a silicon substrate. The proposed method is based on changing the density of state (DOS) of a graphene sheet during the gas absorption. Fabrication of the carbon nanotube (CNT) and graphene based device for gas detection includes silicon micro machining and the growth of vertically aligned CNTs. Field emission between the as-grown CNTs and the graphene sheet which is placed on top of the CNTs is measured at a liquid nitrogen temperature to obtain the DOS of the structure in different gas environments. The measured local DOS of the structure using the fabricated device showed that each gas had its own signatory spectrum. We believe that this method will open up a new and simple way of fabricating a portable gas spectroscope.
Computerized Design of Low-noise Face-milled Spiral Bevel Gears
NASA Technical Reports Server (NTRS)
Litvin, Faydor L.; Zhang, YI; Handschuh, Robert F.
1994-01-01
An advanced design methodology is proposed for the face-milled spiral bevel gears with modified tooth surface geometry that provides a reduced level of noise and has a stabilized bearing contact. The approach is based on the local synthesis of the gear drive that provides the 'best' machine-tool settings. The theoretical aspects of the local synthesis approach are based on the application of a predesigned parabolic function for absorption of undesirable transmission errors caused by misalignment and the direct relations between principal curvatures and directions for mating surfaces. The meshing and contact of the gear drive is synthesized and analyzed by a computer program. The generation of gears with the proposed geometry design can be accomplished by application of existing equipment. A numerical example that illustrates the proposed theory is presented.
Computerized design of low-noise face-milled spiral bevel gears
NASA Astrophysics Data System (ADS)
Litvin, Faydor L.; Zhang, Yi; Handschuh, Robert F.
1994-08-01
An advanced design methodology is proposed for the face-milled spiral bevel gears with modified tooth surface geometry that provides a reduced level of noise and has a stabilized bearing contact. The approach is based on the local synthesis of the gear drive that provides the 'best' machine-tool settings. The theoretical aspects of the local synthesis approach are based on the application of a predesigned parabolic function for absorption of undesirable transmission errors caused by misalignment and the direct relations between principal curvatures and directions for mating surfaces. The meshing and contact of the gear drive is synthesized and analyzed by a computer program. The generation of gears with the proposed geometry design can be accomplished by application of existing equipment. A numerical example that illustrates the proposed theory is presented.
NASA Astrophysics Data System (ADS)
Li, Guoxin; Tang, Xiaoning; Zhang, Xiaoxiao; Qian, Y. J.; Kong, Deyi
2017-11-01
Flexible micro-perforated panel has unique advantages in noise reduction due to its good flexibility compared with traditional rigid micro-perforated panel. In this paper, flexible micro-perforated panel was prepared by computer numerical control (CNC) milling machine. Three kinds of plastics including polyvinylchloride (PVC), polyethylene terephthalate (PET), and polyimide (PI) were taken as the matrix materials to prepare flexible micro-perforated panel. It has been found that flexible micro-perforated panel made of PET possessing good porosity and proper density, elastic modulus and poisson ratio exhibited the best acoustic absorption properties. The effects of various structural parameters including perforation diameter, perforation ratio, thickness and air gap have also been investigated, which would be helpful to the optimization of acoustic absorption properties.
Effects of Perforation on Rigid PU Foam Plates: Acoustic and Mechanical Properties
Lin, Jia-Horng; Chuang, Yu-Chun; Li, Ting-Ting; Huang, Chen-Hung; Huang, Chien-Lin; Chen, Yueh-Sheng; Lou, Ching-Wen
2016-01-01
Factories today are equipped with diverse mechanical equipment in response to rapid technological and industrial developments. Industrial areas located near residential neighborhoods cause massive environmental problems. In particular, noise pollution results in physical and psychological discomfort, and is a seen as invisible and inevitable problem. Thus, noise reduction is a critical and urgent matter. In this study, rigid polyurethane (PU) foam plates undergo perforation using a tapping machine. The mechanical and acoustic properties of these perforated plates as related to perforation rate and perforation depth are evaluated in terms of compression strength, drop-weight impact strength, and sound absorption coefficient. Experimental results indicate that applying the perforation process endows the rigid PU foaming plates with greater load absorption and better sound absorption at medium and high frequencies. PMID:28774119
Effects of Perforation on Rigid PU Foam Plates: Acoustic and Mechanical Properties.
Lin, Jia-Horng; Chuang, Yu-Chun; Li, Ting-Ting; Huang, Chen-Hung; Huang, Chien-Lin; Chen, Yueh-Sheng; Lou, Ching-Wen
2016-12-09
Factories today are equipped with diverse mechanical equipment in response to rapid technological and industrial developments. Industrial areas located near residential neighborhoods cause massive environmental problems. In particular, noise pollution results in physical and psychological discomfort, and is a seen as invisible and inevitable problem. Thus, noise reduction is a critical and urgent matter. In this study, rigid polyurethane (PU) foam plates undergo perforation using a tapping machine. The mechanical and acoustic properties of these perforated plates as related to perforation rate and perforation depth are evaluated in terms of compression strength, drop-weight impact strength, and sound absorption coefficient. Experimental results indicate that applying the perforation process endows the rigid PU foaming plates with greater load absorption and better sound absorption at medium and high frequencies.
NASA Astrophysics Data System (ADS)
Li, Ming; Jiang, Hongyi; Xu, Dong
2018-04-01
Polyurethane sponge-reinforced silica aerogels based on tetraethoxysilane (TEOS) and methyltrimethoxysilane (MTMS) were fabricated by a facile method through sol-gel reaction followed by ambient pressure drying. In sponge-reinforced silica aerogels, nanoporous aerogel aggregates fill in the pores of polyurethane sponge. The sponge-reinforced aerogels are hydrophobic and oleophilic and show extremely high absorption for machine oil (10.6 g g‑1 for TEOS-based aerogel and 9.2 g g‑1 for MTMS-based aerogel). In addition, the sponge-reinforced aerogel composites exhibit notable improvements with regards to mechanical properties. The compressive strength was enhanced obviously up to about 349 KPa for TEOS-based aerogel and 60 KPa for MTMS-based aerogel. Specially, sponge-reinforced silica aerogels based on MTMS drastically shrank upon loading and then recovered to the original size when unloaded. The property differences of the sponge-reinforced silica aerogels caused by the two precursors were discussed in terms of morphologies, pore size distributions and chemical structure.
Terahertz spectroscopic investigation of human gastric normal and tumor tissues
NASA Astrophysics Data System (ADS)
Hou, Dibo; Li, Xian; Cai, Jinhui; Ma, Yehao; Kang, Xusheng; Huang, Pingjie; Zhang, Guangxin
2014-09-01
Human dehydrated normal and cancerous gastric tissues were measured using transmission time-domain terahertz spectroscopy. Based on the obtained terahertz absorption spectra, the contrasts between the two kinds of tissue were investigated and techniques for automatic identification of cancerous tissue were studied. Distinctive differences were demonstrated in both the shape and amplitude of the absorption spectra between normal and tumor tissue. Additionally, some spectral features in the range of 0.2~0.5 THz and 1~1.5 THz were revealed for all cancerous gastric tissues. To systematically achieve the identification of gastric cancer, principal component analysis combined with t-test was used to extract valuable information indicating the best distinction between the two types. Two clustering approaches, K-means and support vector machine (SVM), were then performed to classify the processed terahertz data into normal and cancerous groups. SVM presented a satisfactory result with less false classification cases. The results of this study implicate the potential of the terahertz technique to detect gastric cancer. The applied data analysis methodology provides a suggestion for automatic discrimination of terahertz spectra in other applications.
Sub-diffraction limit laser ablation via multiple exposures using a digital micromirror device.
Heath, Daniel J; Grant-Jacob, James A; Feinaeugle, Matthias; Mills, Ben; Eason, Robert W
2017-08-01
We present the use of digital micromirror devices as variable illumination masks for pitch-splitting multiple exposures to laser machine the surfaces of materials. Ultrafast laser pulses of length 150 fs and 800 nm central wavelength were used for the sequential machining of contiguous patterns on the surface of samples in order to build up complex structures with sub-diffraction limit features. Machined patterns of tens to hundreds of micrometers in lateral dimensions with feature separations as low as 270 nm were produced in electroless nickel on an optical setup diffraction limited to 727 nm, showing a reduction factor below the Abbe diffraction limit of ∼2.7×. This was compared to similar patterns in a photoresist optimized for two-photon absorption, which showed a reduction factor of only 2×, demonstrating that multiple exposures via ablation can produce a greater resolution enhancement than via two-photon polymerization.
NASA Astrophysics Data System (ADS)
Kistenev, Yury V.; Borisov, Alexey V.; Kuzmin, Dmitry A.; Bulanova, Anna A.
2016-08-01
Technique of exhaled breath sampling is discussed. The procedure of wavelength auto-calibration is proposed and tested. Comparison of the experimental data with the model absorption spectra of 5% CO2 is conducted. The classification results of three study groups obtained by using support vector machine and principal component analysis methods are presented.
Baynes, Ronald E; Brooks, James D; Barlow, Beth M; Riviere, Jim E
2002-06-01
Linear alkylbenzene sulfonate (LAS) is added to cutting fluid formulations to enhance the performance of metal machining operations, but this surfactant can cause contact dermatitis in workers involved in these operations. The purpose of this study was to determine how cutting fluid additives influence dermal disposition of 14C-LAS in mineral oil- or polyethylene glycol 200 (PEG)-based mixtures when topically applied to silastic membranes and porcine skin in an in vitro flow-through diffusion cell system. 14C-LAS mixtures were formulated with three commonly used cutting fluid additives; 0 or 2% triazine (TRI), 0 or 5% triethanolamine (TEA), and 0 or 5% sulfurized ricinoleic acid (SRA). LAS absorption was limited to less than a 0.5% dose and the additives in various combinations influenced the physicochemical characteristics of the dosing mixture. LAS was more likely to partition into the stratum corneum (SC) in mineral oil mixtures, and LAS absorption was significantly greater in the complete mixture. TRI enhanced LAS transport, and the presence of SRA decreased LAS critical micelle concentration (CMC) which reduced LAS monomers available for transport. TEA increased mixture viscosity, and this may have negated the apparent enhancing properties of TRI in several mixtures. In summary, physicochemical interactions in these mixtures influenced availability of LAS for absorption and distribution in skin, and could ultimately influence toxicological responses in skin.
The Next Era: Deep Learning in Pharmaceutical Research.
Ekins, Sean
2016-11-01
Over the past decade we have witnessed the increasing sophistication of machine learning algorithms applied in daily use from internet searches, voice recognition, social network software to machine vision software in cameras, phones, robots and self-driving cars. Pharmaceutical research has also seen its fair share of machine learning developments. For example, applying such methods to mine the growing datasets that are created in drug discovery not only enables us to learn from the past but to predict a molecule's properties and behavior in future. The latest machine learning algorithm garnering significant attention is deep learning, which is an artificial neural network with multiple hidden layers. Publications over the last 3 years suggest that this algorithm may have advantages over previous machine learning methods and offer a slight but discernable edge in predictive performance. The time has come for a balanced review of this technique but also to apply machine learning methods such as deep learning across a wider array of endpoints relevant to pharmaceutical research for which the datasets are growing such as physicochemical property prediction, formulation prediction, absorption, distribution, metabolism, excretion and toxicity (ADME/Tox), target prediction and skin permeation, etc. We also show that there are many potential applications of deep learning beyond cheminformatics. It will be important to perform prospective testing (which has been carried out rarely to date) in order to convince skeptics that there will be benefits from investing in this technique.
NASA Astrophysics Data System (ADS)
Mofavvaz, Shirin; Sohrabi, Mahmoud Reza; Nezamzadeh-Ejhieh, Alireza
2017-07-01
In the present study, artificial neural networks (ANNs) and least squares support vector machines (LS-SVM) as intelligent methods based on absorption spectra in the range of 230-300 nm have been used for determination of antihistamine decongestant contents. In the first step, one type of network (feed-forward back-propagation) from the artificial neural network with two different training algorithms, Levenberg-Marquardt (LM) and gradient descent with momentum and adaptive learning rate back-propagation (GDX) algorithm, were employed and their performance was evaluated. The performance of the LM algorithm was better than the GDX algorithm. In the second one, the radial basis network was utilized and results compared with the previous network. In the last one, the other intelligent method named least squares support vector machine was proposed to construct the antihistamine decongestant prediction model and the results were compared with two of the aforementioned networks. The values of the statistical parameters mean square error (MSE), Regression coefficient (R2), correlation coefficient (r) and also mean recovery (%), relative standard deviation (RSD) used for selecting the best model between these methods. Moreover, the proposed methods were compared to the high- performance liquid chromatography (HPLC) as a reference method. One way analysis of variance (ANOVA) test at the 95% confidence level applied to the comparison results of suggested and reference methods that there were no significant differences between them.
The differential absorption hard x-ray spectrometer at the Z facility
Bell, Kate S.; Coverdale, Christine A.; Ampleford, David J.; ...
2017-08-03
The Differential Absorption Hard X-ray (DAHX) spectrometer is a diagnostic developed to measure time-resolved radiation between 60 keV and 2 MeV at the Z Facility. It consists of an array of 7 Si PIN diodes in a tungsten housing that provides collimation and coarse spectral resolution through differential filters. DAHX is a revitalization of the Hard X-Ray Spectrometer (HXRS) that was fielded on Z prior to refurbishment in 2006. DAHX has been tailored to the present radiation environment in Z to provide information on the power, spectral shape, and time profile of the hard emission by plasma radiation sources drivenmore » by the Z Machine.« less
Machine Learning and Experimental Design for Hydrogen Cosmology
NASA Astrophysics Data System (ADS)
Rapetti, David; Tauscher, Keith A.; Burns, Jack O.; Mirocha, Jordan; Switzer, Eric; Monsalve, Raul A.; Furlanetto, Steven R.; Bowman, Judd D.
2018-06-01
Based on two powerful innovations, we present a new pipeline to analyze the redshifted sky-averaged 21-cm spectrum (~10-200 MHz) of neutral hydrogen from the first stars, galaxies and black holes. First, we combine machine learning and model selection techniques to extract the global 21-cm signal from foreground and instrumental systematics. Second, we employ experimental designs to increase our ability to separate these two components in data sets. For measurements with foreground polarization induced by rotation about the anisotropic low-frequency radio sky on a large beam, we incorporate this information into the likelihood to distinguish the unpolarized 21-cm signal from the rest of the data. For experiments with a drift scan strategy, we take advantage of the varying foreground in time to identify the constant 21-cm signal. This pipeline can be applied to either lunar orbit/surface instruments shielded from terrestrial and solar radio contamination, or existing ground-based observations, such as those from the EDGES collaboration that recently observed an absorption trough potentially consistent with the global 21-cm signal of Cosmic Dawn. Finally, this pipeline allows us to constrain physical parameters for a given model of the first luminous objects plus exotic physics in the early universe, from e.g. dark matter, through an MCMC analysis that uses the extracted signal as a starting point, providing key efficiency for unexplored cosmologies.
Classification of river water pollution using Hyperion data
NASA Astrophysics Data System (ADS)
Kar, Soumyashree; Rathore, V. S.; Champati ray, P. K.; Sharma, Richa; Swain, S. K.
2016-06-01
A novel attempt is made to use hyperspectral remote sensing to identify the spatial variability of metal pollutants present in river water. It was also attempted to classify the hyperspectral image - Earth Observation-1 (EO-1) Hyperion data of an 8 km stretch of the river Yamuna, near Allahabad city in India depending on its chemical composition. For validating image analysis results, a total of 10 water samples were collected and chemically analyzed using Inductively Coupled Plasma-Optical Emission Spectroscopy (ICP-OES). Two different spectral libraries from field and image data were generated for the 10 sample locations. Advanced per-pixel supervised classifications such as Spectral Angle Mapper (SAM), SAM target finder using BandMax and Support Vector Machine (SVM) were carried out along with the unsupervised clustering procedure - Iterative Self-Organizing Data Analysis Technique (ISODATA). The results were compared and assessed with respect to ground data. Analytical Spectral Devices (ASD), Inc. spectroradiometer, FieldSpec 4 was used to generate the spectra of the water samples which were compiled into a spectral library and used for Spectral Absorption Depth (SAD) analysis. The spectral depth pattern of image and field spectral libraries was found to be highly correlated (correlation coefficient, R2 = 0.99) which validated the image analysis results with respect to the ground data. Further, we carried out a multivariate regression analysis to assess the varying concentrations of metal ions present in water based on the spectral depth of the corresponding absorption feature. Spectral Absorption Depth (SAD) analysis along with metal analysis of field data revealed the order in which the metals affected the river pollution, which was in conformity with the findings of Central Pollution Control Board (CPCB). Therefore, it is concluded that hyperspectral imaging provides opportunity that can be used for satellite based remote monitoring of water quality from space.
NASA Astrophysics Data System (ADS)
Mitri, F. G.
2016-10-01
Based on the angular spectrum decomposition method (ASDM), a nonparaxial solution for the Hermite-Gaussian (HG m ) light-sheet beam of any order m is derived. The beam-shape coefficients (BSCs) are expressed in a compact form and computed using the standard Simpson’s rule for numerical integration. Subsequently, the analysis is extended to evaluate the longitudinal and transverse radiation forces as well as the spin torque on an absorptive dielectric cylindrical particle in 2D without any restriction to a specific range of frequencies. The dynamics of the cylindrical particle are also examined based on Newton’s second law of motion. The numerical results show that a Rayleigh or Mie cylindrical particle can be trapped, pulled or propelled in the optical field depending on its initial position in the cross-sectional plane of the HG m light-sheet. Moreover, negative or positive axial spin torques can arise depending on the choice of the non-dimensional size parameter ka (where k is the wavenumber and a is the radius of the cylinder) and the location of the absorptive cylinder in the beam. This means that the HG m light-sheet beam can induce clockwise or anti-clockwise rotations depending on its shift from the center of the cylinder. In addition, individual vortex behavior can arise in the cross-sectional plane of wave propagation. The present analysis presents an analytical model to predict the optical radiation forces and torque induced by a HG m light-sheet beam on an absorptive cylinder for applications in optical light-sheet tweezers, optical micro-machines, particle manipulation and opto-fluidics to name a few areas of research.
The Next Era: Deep Learning in Pharmaceutical Research
Ekins, Sean
2016-01-01
Over the past decade we have witnessed the increasing sophistication of machine learning algorithms applied in daily use from internet searches, voice recognition, social network software to machine vision software in cameras, phones, robots and self-driving cars. Pharmaceutical research has also seen its fair share of machine learning developments. For example, applying such methods to mine the growing datasets that are created in drug discovery not only enables us to learn from the past but to predict a molecule’s properties and behavior in future. The latest machine learning algorithm garnering significant attention is deep learning, which is an artificial neural network with multiple hidden layers. Publications over the last 3 years suggest that this algorithm may have advantages over previous machine learning methods and offer a slight but discernable edge in predictive performance. The time has come for a balanced review of this technique but also to apply machine learning methods such as deep learning across a wider array of endpoints relevant to pharmaceutical research for which the datasets are growing such as physicochemical property prediction, formulation prediction, absorption, distribution, metabolism, excretion and toxicity (ADME/Tox), target prediction and skin permeation, etc. We also show that there are many potential applications of deep learning beyond cheminformatics. It will be important to perform prospective testing (which has been carried out rarely to date) in order to convince skeptics that there will be benefits from investing in this technique. PMID:27599991
Federal Register 2010, 2011, 2012, 2013, 2014
2011-12-28
... Determination Concerning Laser-Based Multi-Function Office Machines AGENCY: U.S. Customs and Border Protection... country of origin of laser-based multi-function office machines. Based upon the facts presented, CBP has... essential character of the laser-based multi-function office machine, and it is at their assembly and...
NASA Astrophysics Data System (ADS)
Li, Q. S.; Wong, F. K. K.; Fung, T.
2017-08-01
Lightweight unmanned aerial vehicle (UAV) loaded with novel sensors offers a low cost and minimum risk solution for data acquisition in complex environment. This study assessed the performance of UAV-based hyperspectral image and digital surface model (DSM) derived from photogrammetric point clouds for 13 species classification in wetland area of Hong Kong. Multiple feature reduction methods and different classifiers were compared. The best result was obtained when transformed components from minimum noise fraction (MNF) and DSM were combined in support vector machine (SVM) classifier. Wavelength regions at chlorophyll absorption green peak, red, red edge and Oxygen absorption at near infrared were identified for better species discrimination. In addition, input of DSM data reduces overestimation of low plant species and misclassification due to the shadow effect and inter-species morphological variation. This study establishes a framework for quick survey and update on wetland environment using UAV system. The findings indicate that the utility of UAV-borne hyperspectral and derived tree height information provides a solid foundation for further researches such as biological invasion monitoring and bio-parameters modelling in wetland.
The spectral analysis of fuel oils using terahertz radiation and chemometric methods
NASA Astrophysics Data System (ADS)
Zhan, Honglei; Zhao, Kun; Zhao, Hui; Li, Qian; Zhu, Shouming; Xiao, Lizhi
2016-10-01
The combustion characteristics of fuel oils are closely related to both engine efficiency and pollutant emissions, and the analysis of oils and their additives is thus important. These oils and additives have been found to generate distinct responses to terahertz (THz) radiation as the result of various molecular vibrational modes. In the present work, THz spectroscopy was employed to identify a number of oils, including lubricants, gasoline and diesel, with different additives. The identities of dozens of these oils could be readily established using statistical models based on principal component analysis. The THz spectra of gasoline, diesel, sulfur and methyl methacrylate (MMA) were acquired and linear fittings were obtained. By using chemometric methods, including back propagation, artificial neural network and support vector machine techniques, typical concentrations of sulfur in gasoline (ppm-grade) could be detected, together with MMA in diesel below 0.5%. The absorption characteristics of the oil additives were also assessed using 2D correlation spectroscopy, and several hidden absorption peaks were discovered. The technique discussed herein should provide a useful new means of analyzing fuel oils with various additives and impurities in a non-destructive manner and therefore will be of benefit to the field of chemical detection and identification.
A random forest algorithm for nowcasting of intense precipitation events
NASA Astrophysics Data System (ADS)
Das, Saurabh; Chakraborty, Rohit; Maitra, Animesh
2017-09-01
Automatic nowcasting of convective initiation and thunderstorms has potential applications in several sectors including aviation planning and disaster management. In this paper, random forest based machine learning algorithm is tested for nowcasting of convective rain with a ground based radiometer. Brightness temperatures measured at 14 frequencies (7 frequencies in 22-31 GHz band and 7 frequencies in 51-58 GHz bands) are utilized as the inputs of the model. The lower frequency band is associated to the water vapor absorption whereas the upper frequency band relates to the oxygen absorption and hence, provide information on the temperature and humidity of the atmosphere. Synthetic minority over-sampling technique is used to balance the data set and 10-fold cross validation is used to assess the performance of the model. Results indicate that random forest algorithm with fixed alarm generation time of 30 min and 60 min performs quite well (probability of detection of all types of weather condition ∼90%) with low false alarms. It is, however, also observed that reducing the alarm generation time improves the threat score significantly and also decreases false alarms. The proposed model is found to be very sensitive to the boundary layer instability as indicated by the variable importance measure. The study shows the suitability of a random forest algorithm for nowcasting application utilizing a large number of input parameters from diverse sources and can be utilized in other forecasting problems.
Method and system for fault accommodation of machines
NASA Technical Reports Server (NTRS)
Goebel, Kai Frank (Inventor); Subbu, Rajesh Venkat (Inventor); Rausch, Randal Thomas (Inventor); Frederick, Dean Kimball (Inventor)
2011-01-01
A method for multi-objective fault accommodation using predictive modeling is disclosed. The method includes using a simulated machine that simulates a faulted actual machine, and using a simulated controller that simulates an actual controller. A multi-objective optimization process is performed, based on specified control settings for the simulated controller and specified operational scenarios for the simulated machine controlled by the simulated controller, to generate a Pareto frontier-based solution space relating performance of the simulated machine to settings of the simulated controller, including adjustment to the operational scenarios to represent a fault condition of the simulated machine. Control settings of the actual controller are adjusted, represented by the simulated controller, for controlling the actual machine, represented by the simulated machine, in response to a fault condition of the actual machine, based on the Pareto frontier-based solution space, to maximize desirable operational conditions and minimize undesirable operational conditions while operating the actual machine in a region of the solution space defined by the Pareto frontier.
Using the Properties of Broad Absorption Line Quasars to Illuminate Quasar Structure
NASA Astrophysics Data System (ADS)
Yong, Suk Yee; King, Anthea L.; Webster, Rachel L.; Bate, Nicholas F.; O'Dowd, Matthew J.; Labrie, Kathleen
2018-06-01
A key to understanding quasar unification paradigms is the emission properties of broad absorption line quasars (BALQs). The fact that only a small fraction of quasar spectra exhibit deep absorption troughs blueward of the broad permitted emission lines provides a crucial clue to the structure of quasar emitting regions. To learn whether it is possible to discriminate between the BALQ and non-BALQ populations given the observed spectral properties of a quasar, we employ two approaches: one based on statistical methods and the other supervised machine learning classification, applied to quasar samples from the Sloan Digital Sky Survey. The features explored include continuum and emission line properties, in particular the absolute magnitude, redshift, spectral index, line width, asymmetry, strength, and relative velocity offsets of high-ionisation C IV λ1549 and low-ionisation Mg II λ2798 lines. We consider a complete population of quasars, and assume that the statistical distributions of properties represent all angles where the quasar is viewed without obscuration. The distributions of the BALQ and non-BALQ sample properties show few significant differences. None of the observed continuum and emission line features are capable of differentiating between the two samples. Most published narrow disk-wind models are inconsistent with these observations, and an alternative disk-wind model is proposed. The key feature of the proposed model is a disk-wind filling a wide opening angle with multiple radial streams of dense clumps.
Machine Learning Based Malware Detection
2015-05-18
A TRIDENT SCHOLAR PROJECT REPORT NO. 440 Machine Learning Based Malware Detection by Midshipman 1/C Zane A. Markel, USN...COVERED (From - To) 4. TITLE AND SUBTITLE Machine Learning Based Malware Detection 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM...suitably be projected into realistic performance. This work explores several aspects of machine learning based malware detection . First, we
Layouts of trigeneration plants for centralized power supply
NASA Astrophysics Data System (ADS)
Klimenko, A. V.; Agababov, V. S.; Il'ina, I. P.; Rozhnatovskii, V. D.; Burmakina, A. V.
2016-06-01
One of the possible and, under certain conditions, sufficiently effective methods for reducing consumption of fuel and energy resources is the development of plants for combined generation of different kinds of energy. In the power industry of Russia, the facilities have become widespread in which the cogeneration technology, i.e., simultaneous generation of electric energy and heat, is implemented. Such facilities can use different plants, viz., gas- and steam-turbine plants and gas-reciprocating units. Cogeneration power supply can be further developed by simultaneously supplying the users not only with electricity and heat but also with cold. Such a technology is referred to as trigeneration. To produce electricity and heat, trigeneration plants can use the same facilities that are used in cogeneration, namely, gas-turbine plants, steam-turbine plants, and gas-reciprocating units. Cold can be produced in trigeneration plants using thermotransformers of various kinds, such as vaporcompression thermotransformers, air thermotransformers, and absorption thermotransformers, that operate as chilling machines. The thermotransformers can also be used in the trigeneration plants to generate heat. The main advantage of trigeneration plants based on gas-turbine plants or gas-reciprocating units over cogeneration plants is the increased thermodynamic power supply efficiency owing to utilization of the waste-gas heat not only in winter but also in summer. In the steam-turbine-based trigeneration plants equipped with absorption thermotransformers, the enhancement of the thermodynamic power supply efficiency is determined by the increase in the heat extraction load during the nonheating season. The article presents calculated results that demonstrate higher thermodynamic efficiency of a gas-turbine-based plant with an absorption thermotransformer that operates in the trigeneration mode compared with a cogeneration gas-turbine plant. The structural arrangements of trigeneration plants designed to supply electricity, heat, and cold to the users are shown and the principles of their operation are described. The article presents results of qualitative analysis of different engineering solutions applied to select one combination of power- and heat-generating equipment and thermotransformers or another.
Status of the NASA-Lewis flat-plate collector tests with a solar simulator
NASA Technical Reports Server (NTRS)
Simon, F. F.
1974-01-01
Simulator test results of 15 collector types are presented. Collectors are given performance ratings according to their use for pool heating, hot water, absorption A/C or heating, and solar Rankine machines. Collectors found to be good performers in the above categories, except for pool heating, were a black nickel coated, 2 glass collector, and a black paint 2 glass collector containing a mylar honeycomb. For pool heating, a black paint, one glass collector was found to be the best performer. Collector performance parameters of 5 collector types were determined to aid in explaining the factors that govern performance. The two factors that had the greatest effect on collector performance were the collector heat loss and the coating absorptivity.
Optical detection techniques for laser sorting machines
NASA Astrophysics Data System (ADS)
Meulebroeck, W.; Thienpont, H.
2006-04-01
In this work we summarize some of the results we obtained during our research of different physical phenomena which take place when a visible or near-infrared laser beam falls in onto a biological product, more in particular on a vegetable or on a fruit. The most important phenomena are surface reflection, selective absorption, fluorescence, absorption in the near-infrared and internal reflection. While the emphasis lays on the identification of the product type we will show that some of the demonstrated sorting principles can also be used for quality sorting: for example a determination of the ripeness of green vegetables or of the water/oil content of vegetables and fruits and a detection of the presence of the very harmful aflatoxines.
ADRPM-VII applied to the long-range acoustic detection problem
NASA Technical Reports Server (NTRS)
Shalis, Edward; Koenig, Gerald
1990-01-01
An acoustic detection range prediction model (ADRPM-VII) has been written for IBM PC/AT machines running on the MS-DOS operating system. The software allows the user to predict detection distances of ground combat vehicles and their associated targets when they are involved in quasi-military settings. The program can also calculate individual attenuation losses due to spherical spreading, atmospheric absorption, ground reflection and atmospheric refraction due to temperature and wind gradients while varying parameters effecting the source-receiver problem. The purpose here is to examine the strengths and limitations of ADRPM-VII by modeling the losses due to atmospheric refraction and ground absorption, commonly known as excess attenuation, when applied to the long range detection problem for distances greater than 3 kilometers.
Marabel, Miguel; Alvarez-Taboada, Flor
2013-01-01
Aboveground biomass (AGB) is one of the strategic biophysical variables of interest in vegetation studies. The main objective of this study was to evaluate the Support Vector Machine (SVM) and Partial Least Squares Regression (PLSR) for estimating the AGB of grasslands from field spectrometer data and to find out which data pre-processing approach was the most suitable. The most accurate model to predict the total AGB involved PLSR and the Maximum Band Depth index derived from the continuum removed reflectance in the absorption features between 916–1,120 nm and 1,079–1,297 nm (R2 = 0.939, RMSE = 7.120 g/m2). Regarding the green fraction of the AGB, the Area Over the Minimum index derived from the continuum removed spectra provided the most accurate model overall (R2 = 0.939, RMSE = 3.172 g/m2). Identifying the appropriate absorption features was proved to be crucial to improve the performance of PLSR to estimate the total and green aboveground biomass, by using the indices derived from those spectral regions. Ordinary Least Square Regression could be used as a surrogate for the PLSR approach with the Area Over the Minimum index as the independent variable, although the resulting model would not be as accurate. PMID:23925082
Dynamic impact testing with servohydraulic testing machines
NASA Astrophysics Data System (ADS)
Bardenheier, R.; Rogers, G.
2006-08-01
The design concept of “Crashworthiness” requires the information on material behaviour under dynamic impact loading in order to describe and predict the crash behaviour of structures. Especially the transport related industries, like car, railway or aircraft industry, pursue the concept of lightweight design for a while now. The materials' maximum constraint during loading is pushed to permanently increasing figures. This means in terms of crashworthiness that the process of energy absorption in structures and the mechanical behaviour of materials must well understood and can be described appropriately by material models. In close cooperation with experts from various industries and research institutes Instron has developed throughout the past years a new family of servohydraulic testing machines specifically designed to cope with the dynamics of high rate testing. Main development steps are reflected versus their experimental necessities.
ERIC Educational Resources Information Center
Mississippi Research and Curriculum Unit for Vocational and Technical Education, State College.
This document, which reflects Mississippi's statutory requirement that instructional programs be based on core curricula and performance-based assessment, contains outlines of the instructional units required in local instructional management plans and daily lesson plans for machine tool operation/machine shop I and II. Presented first are a…
NASA Astrophysics Data System (ADS)
Zhao, Yinan; Ge, Jian; Yuan, Xiaoyong; Li, Xiaolin; Zhao, Tiffany; Wang, Cindy
2018-01-01
Metal absorption line systems in the distant quasar spectra have been used as one of the most powerful tools to probe gas content in the early Universe. The MgII λλ 2796, 2803 doublet is one of the most popular metal absorption lines and has been used to trace gas and global star formation at redshifts between ~0.5 to 2.5. In the past, machine learning algorithms have been used to detect absorption lines systems in the large sky survey, such as Principle Component Analysis, Gaussian Process and decision tree, but the overall detection process is not only complicated, but also time consuming. It usually takes a few months to go through the entire quasar spectral dataset from each of the Sloan Digital Sky Survey (SDSS) data release. In this work, we applied the deep neural network, or “ deep learning” algorithms, in the most recently SDSS DR14 quasar spectra and were able to randomly search 20000 quasar spectra and detect 2887 strong Mg II absorption features in just 9 seconds. Our detection algorithms were verified with previously released DR12 and DR7 data and published Mg II catalog and the detection accuracy is 90%. This is the first time that deep neural network has demonstrated its promising power in both speed and accuracy in replacing tedious, repetitive human work in searching for narrow absorption patterns in a big dataset. We will present our detection algorithms and also statistical results of the newly detected Mg II absorption lines.
The research on construction and application of machining process knowledge base
NASA Astrophysics Data System (ADS)
Zhao, Tan; Qiao, Lihong; Qie, Yifan; Guo, Kai
2018-03-01
In order to realize the application of knowledge in machining process design, from the perspective of knowledge in the application of computer aided process planning(CAPP), a hierarchical structure of knowledge classification is established according to the characteristics of mechanical engineering field. The expression of machining process knowledge is structured by means of production rules and the object-oriented methods. Three kinds of knowledge base models are constructed according to the representation of machining process knowledge. In this paper, the definition and classification of machining process knowledge, knowledge model, and the application flow of the process design based on the knowledge base are given, and the main steps of the design decision of the machine tool are carried out as an application by using the knowledge base.
Realtime automatic metal extraction of medical x-ray images for contrast improvement
NASA Astrophysics Data System (ADS)
Prangl, Martin; Hellwagner, Hermann; Spielvogel, Christian; Bischof, Horst; Szkaliczki, Tibor
2006-03-01
This paper focuses on an approach for real-time metal extraction of x-ray images taken from modern x-ray machines like C-arms. Such machines are used for vessel diagnostics, surgical interventions, as well as cardiology, neurology and orthopedic examinations. They are very fast in taking images from different angles. For this reason, manual adjustment of contrast is infeasible and automatic adjustment algorithms have been applied to try to select the optimal radiation dose for contrast adjustment. Problems occur when metallic objects, e.g., a prosthesis or a screw, are in the absorption area of interest. In this case, the automatic adjustment mostly fails because the dark, metallic objects lead the algorithm to overdose the x-ray tube. This outshining effect results in overexposed images and bad contrast. To overcome this limitation, metallic objects have to be detected and extracted from images that are taken as input for the adjustment algorithm. In this paper, we present a real-time solution for extracting metallic objects of x-ray images. We will explore the characteristic features of metallic objects in x-ray images and their distinction from bone fragments which form the basis to find a successful way for object segmentation and classification. Subsequently, we will present our edge based real-time approach for successful and fast automatic segmentation and classification of metallic objects. Finally, experimental results on the effectiveness and performance of our approach based on a vast amount of input image data sets will be presented.
Characteristics of Crushing Energy and Fractal of Magnetite Ore under Uniaxial Compression
NASA Astrophysics Data System (ADS)
Gao, F.; Gan, D. Q.; Zhang, Y. B.
2018-03-01
The crushing mechanism of magnetite ore is a critical theoretical problem on the controlling of energy dissipation and machine crushing quality in ore material processing. Uniaxial crushing tests were carried out to research the deformation mechanism and the laws of the energy evolution, based on which the crushing mechanism of magnetite ore was explored. The compaction stage and plasticity and damage stage are two main compression deformation stages, the main transitional forms from inner damage to fracture are plastic deformation and stick-slip. In the process of crushing, plasticity and damage stage is the key link on energy absorption for that the specimen tends to saturate energy state approaching to the peak stress. The characteristics of specimen deformation and energy dissipation can synthetically reply the state of existed defects inner raw magnetite ore and the damage process during loading period. The fast releasing of elastic energy and the work done by the press machine commonly make raw magnetite ore thoroughly broken after peak stress. Magnetite ore fragments have statistical self-similarity and size threshold of fractal characteristics under uniaxial squeezing crushing. The larger ratio of releasable elastic energy and dissipation energy and the faster energy change rate is the better fractal properties and crushing quality magnetite ore has under uniaxial crushing.
Universal modal radiation laws for all thermal emitters
Zhu, Linxiao; Fan, Shanhui
2017-01-01
We derive four laws relating the absorptivity and emissivity of thermal emitters. Unlike the original Kirchhoff radiation law derivations, these derivations include diffraction, and so are valid also for small objects, and can also cover nonreciprocal objects. The proofs exploit two recent approaches. First, we express all fields in terms of the mode-converter basis sets of beams; these sets, which can be uniquely established for any linear optical object, give orthogonal input beams that are coupled one-by-one to orthogonal output beams. Second, we consider thought experiments using universal linear optical machines, which allow us to couple appropriate beams and black bodies. Two of these laws can be regarded as rigorous extensions of previously known laws: One gives a modal version of a radiation law for reciprocal objects—the absorptivity of any input beam equals the emissivity into the “backward” (i.e., phase-conjugated) version of that beam; another gives the overall equality of the sums of the emissivities and the absorptivities for any object, including nonreciprocal ones. The other two laws, valid for reciprocal and nonreciprocal objects, are quite different from previous relations. One shows universal equivalence of the absorptivity of each mode-converter input beam and the emissivity into its corresponding scattered output beam. The other gives unexpected equivalences of absorptivity and emissivity for broad classes of beams. Additionally, we prove these orthogonal mode-converter sets of input and output beams are the ones that maximize absorptivities and emissivities, respectively, giving these beams surprising additional physical meaning. PMID:28396436
Dynamic Testing of Signal Transduction Deregulation During Breast Cancer Initiation
2011-07-01
1 at a chamber pressure of ~3 × 10-6 Torr for the electron beam evaporated films. A Hitachi FB2100 Focused Ion Beam milling machine with a gallium ...immobilization. These include physical absorption, layer-by-layer (LBL) assembly, and covalent attachment, and eventually chose the covalent attachment...testing real-time signaling in live breast cancer cells, it is important to evaluate the nanosensors to monitor fluorescent compounds in single
NASA Astrophysics Data System (ADS)
Ben Mohammadi, L.; Kullmann, F.; Holzki, M.; Sigloch, S.; Klotzbuecher, T.; Spiesen, J.; Tommingas, T.; Weismann, P.; Kimber, G.
2010-04-01
The chemical and physical condition of oils in marine engines must be monitored to ensure optimum performance of the engine and to avoid damage by degraded oil not adequately lubricating the engine. Routine monitoring requires expensive laboratory testing and highly skilled analysts. This work describes the adaptation and implementation of a mid infrared (MIR) sensor module for continued oil condition monitoring in two-stroke and four-stroke diesel engines. The developed sensor module will help to reduce costs in oil analysis by eliminating the need to collect and send samples to a laboratory for analysis. The online MIR-Sensor module measures the contamination of oil with water, soot, as well as the degradation indicated by the TBN (Total Base Number) value. For the analysis of water, TBN, and soot in marine engine oils, four spectral regions of interest have been identified. The optical absorption in these bands correlating with the contaminations is measured simultaneously by using a four-field thermopile detector, combined with appropriate bandpass filters. Recording of the MIR-absorption was performed in a transmission mode using a flow-through cell with appropriate path length. Since in this case no spectrometer is required, the sensor including the light source, the flowthrough- cell, and the detector can be realised at low cost and in a very compact manner. The optical configuration of the sensor with minimal component number and signal intensity optimisation at the four-field detector was implemented by using non-sequential ray tracing simulation. The used calibration model was robust enough to predict accurately the value for soot, water, and TBN concentration for two-stroke and four-stroke engine oils. The sensor device is designed for direct installation on the host engine or machine and, therefore, becoming an integral part of the lubrication system. It can also be used as a portable stand-alone system for machine fluid analysis in the field.
Bagheri, Hossein; Hooshmand, Tabassom; Aghajani, Farzaneh
2015-09-01
This study aimed to evaluate the effect of different ceramic surface treatments after machining grinding on the biaxial flexural strength (BFS) of machinable dental ceramics with different crystalline phases. Disk-shape specimens (10mm in diameter and 1.3mm in thickness) of machinable ceramic cores (two silica-based and one zirconia-based ceramics) were prepared. Each type of the ceramic surfaces was then randomly treated (n=15) with different treatments as follows: 1) machined finish as control, 2) machined finish and sandblasting with alumina, and 3) machined finish and hydrofluoric acid etching for the leucite and lithium disilicate-based ceramics, and for the zirconia; 1) machined finish and post-sintered as control, 2) machined finish, post-sintered, and sandblasting, and 3) machined finish, post-sintered, and Nd;YAG laser irradiation. The BFS were measured in a universal testing machine. Data based were analyzed by ANOVA and Tukey's multiple comparisons post-hoc test (α=0.05). The mean BFS of machined finish only surfaces for leucite ceramic was significantly higher than that of sandblasted (P=0.001) and acid etched surfaces (P=0.005). A significantly lower BFS was found after sandblasting for lithium disilicate compared with that of other groups (P<0.05). Sandblasting significantly increased the BFS for the zirconia (P<0.05), but the BFS was significantly decreased after laser irradiation (P<0.05). The BFS of the machinable ceramics was affected by the type of ceramic material and surface treatment method. Sandblasting with alumina was detrimental to the strength of only silica-based ceramics. Nd:YAG laser irradiation may lead to substantial strength degradation of zirconia.
Bagheri, Hossein; Aghajani, Farzaneh
2015-01-01
Objectives: This study aimed to evaluate the effect of different ceramic surface treatments after machining grinding on the biaxial flexural strength (BFS) of machinable dental ceramics with different crystalline phases. Materials and Methods: Disk-shape specimens (10mm in diameter and 1.3mm in thickness) of machinable ceramic cores (two silica-based and one zirconia-based ceramics) were prepared. Each type of the ceramic surfaces was then randomly treated (n=15) with different treatments as follows: 1) machined finish as control, 2) machined finish and sandblasting with alumina, and 3) machined finish and hydrofluoric acid etching for the leucite and lithium disilicate-based ceramics, and for the zirconia; 1) machined finish and post-sintered as control, 2) machined finish, post-sintered, and sandblasting, and 3) machined finish, post-sintered, and Nd;YAG laser irradiation. The BFS were measured in a universal testing machine. Data based were analyzed by ANOVA and Tukey’s multiple comparisons post-hoc test (α=0.05). Results: The mean BFS of machined finish only surfaces for leucite ceramic was significantly higher than that of sandblasted (P=0.001) and acid etched surfaces (P=0.005). A significantly lower BFS was found after sandblasting for lithium disilicate compared with that of other groups (P<0.05). Sandblasting significantly increased the BFS for the zirconia (P<0.05), but the BFS was significantly decreased after laser irradiation (P<0.05). Conclusions: The BFS of the machinable ceramics was affected by the type of ceramic material and surface treatment method. Sandblasting with alumina was detrimental to the strength of only silica-based ceramics. Nd:YAG laser irradiation may lead to substantial strength degradation of zirconia. PMID:27148372
NASA Astrophysics Data System (ADS)
Yu, Jianbo
2015-12-01
Prognostics is much efficient to achieve zero-downtime performance, maximum productivity and proactive maintenance of machines. Prognostics intends to assess and predict the time evolution of machine health degradation so that machine failures can be predicted and prevented. A novel prognostics system is developed based on the data-model-fusion scheme using the Bayesian inference-based self-organizing map (SOM) and an integration of logistic regression (LR) and high-order particle filtering (HOPF). In this prognostics system, a baseline SOM is constructed to model the data distribution space of healthy machine under an assumption that predictable fault patterns are not available. Bayesian inference-based probability (BIP) derived from the baseline SOM is developed as a quantification indication of machine health degradation. BIP is capable of offering failure probability for the monitored machine, which has intuitionist explanation related to health degradation state. Based on those historic BIPs, the constructed LR and its modeling noise constitute a high-order Markov process (HOMP) to describe machine health propagation. HOPF is used to solve the HOMP estimation to predict the evolution of the machine health in the form of a probability density function (PDF). An on-line model update scheme is developed to adapt the Markov process changes to machine health dynamics quickly. The experimental results on a bearing test-bed illustrate the potential applications of the proposed system as an effective and simple tool for machine health prognostics.
Blast protection of infrastructure using advanced composites
NASA Astrophysics Data System (ADS)
Brodsky, Evan
This research was a systematic investigation detailing the energy absorption mechanisms of an E-glass web core composite sandwich panel subjected to an impulse loading applied orthogonal to the facesheet. Key roles of the fiberglass and polyisocyanurate foam material were identified, characterized, and analyzed. A quasi-static test fixture was used to compressively load a unit cell web core specimen machined from the sandwich panel. The web and foam both exhibited non-linear stress-strain responses during axial compressive loading. Through several analyses, the composite web situated in the web core had failed in axial compression. Optimization studies were performed on the sandwich panel unit cell in order to maximize the energy absorption capabilities of the web core. Ultimately, a sandwich panel was designed to optimize the energy dissipation subjected to through-the-thickness compressive loading.
Silicone absorption of elastomeric closures--an accelerated study.
Degrazio, F L; Hlobik, T; Vaughan, S
1998-01-01
There is a trend in the parenteral industry to move from the use of elastomeric closures which are washed, siliconized, dried and sterilized in-house at the pharmaceutical manufacturers' site to pre-prepared closures purchased from the closure supplier. This preparation can consist of washing to reduce particle-load and bioburden, siliconization, placement in ready-to-sterilize bags and may eventually extend to sterilization by steam autoclave or gamma irradiation. Since silicone oil lubrication is critical to the processability/machinability of closures, research was designed to investigate this phenomenon in closures prepared using the Westar RS (Ready-to-Sterilize) process. This paper presents the data gathered in a study of the characteristic of silicone absorption into elastomeric closures under accelerated conditions. Variables such as silicone viscosity, rubber formulation, effect of sterilization and others are considered.
Nakai, Yasushi; Takiguchi, Tetsuya; Matsui, Gakuyo; Yamaoka, Noriko; Takada, Satoshi
2017-10-01
Abnormal prosody is often evident in the voice intonations of individuals with autism spectrum disorders. We compared a machine-learning-based voice analysis with human hearing judgments made by 10 speech therapists for classifying children with autism spectrum disorders ( n = 30) and typical development ( n = 51). Using stimuli limited to single-word utterances, machine-learning-based voice analysis was superior to speech therapist judgments. There was a significantly higher true-positive than false-negative rate for machine-learning-based voice analysis but not for speech therapists. Results are discussed in terms of some artificiality of clinician judgments based on single-word utterances, and the objectivity machine-learning-based voice analysis adds to judging abnormal prosody.
Learning Machine, Vietnamese Based Human-Computer Interface.
ERIC Educational Resources Information Center
Northwest Regional Educational Lab., Portland, OR.
The sixth session of IT@EDU98 consisted of seven papers on the topic of the learning machine--Vietnamese based human-computer interface, and was chaired by Phan Viet Hoang (Informatics College, Singapore). "Knowledge Based Approach for English Vietnamese Machine Translation" (Hoang Kiem, Dinh Dien) presents the knowledge base approach,…
Machine characterization based on an abstract high-level language machine
NASA Technical Reports Server (NTRS)
Saavedra-Barrera, Rafael H.; Smith, Alan Jay; Miya, Eugene
1989-01-01
Measurements are presented for a large number of machines ranging from small workstations to supercomputers. The authors combine these measurements into groups of parameters which relate to specific aspects of the machine implementation, and use these groups to provide overall machine characterizations. The authors also define the concept of pershapes, which represent the level of performance of a machine for different types of computation. A metric based on pershapes is introduced that provides a quantitative way of measuring how similar two machines are in terms of their performance distributions. The metric is related to the extent to which pairs of machines have varying relative performance levels depending on which benchmark is used.
First results from protective ECRH diagnostics for Wendelstein 7-X
NASA Astrophysics Data System (ADS)
Marsen, S.; Corre, Y.; Laqua, H. P.; Moncada, V.; Moseev, D.; Niemann, H.; Preynas, M.; Stange, T.; The W7-X Team
2017-08-01
Wendelstein 7-X (W7-X) is a steady state capable optimised stellarator. The main heating system is electron cyclotron resonance heating (ECRH) operating at 140 GHz providing up to 9 MW microwave power. The power is launched into the machine by front steerable quasi-optical launchers in X- or O-mode. While in X-mode the first pass absorption is 99%, it is only 40... 70% in O-mode. O2-mode heating is forseen for high density operation above the X2 cutoff density of 1.2\\centerdot {{10}20} m-3. A set of diagnostics has been developed to protect the machine from non absorbed ECRH power which can easily damage in vessel components. The non absorbed power hitting the inner wall is measured by waveguides embedded in the first wall (ECA diagnostic). In order to prevent the inner wall from overheating or arcing, a near-infra red sensitive video diagnostic with a dynamic range of 450...1200 °C was integrated in the ECRH launchers. Thermal calculations for the carbon tiles predict a temperature increase above the detection threshold for scenarios of plasma start-up failure or poor absorption on a time scale of 50 ms. However, the temperature increase measured by an IR camera in experiments with failed break down, i.e. no ECRH absorption for up to 50 ms, was only Δ T≈ 70{{~}\\circ} C. In discharges with ≈ 5% transmission the measured temperature increase was comparable. The stray radiation level inside the machine is measured by so called sniffer probes resembling microwave diode detectors which were designed to collect all radiation approaching the probing surface independent of incident angle and polarization. Five sniffer probes are installed at different toroidal positions. They were integrated in the ECRH interlock system. During the first operational phase of W7-X this was the only available plasma interlock system. The signal quality proofed to be high enough for a reliable termination in case of poor absorption. After a breakdown phase of 10 ms, the sniffer probe signals dropped by more than an order of magnitude. Especially in the very first days of operation, most discharges died by a radiative collapse due to impurity influx. In this case the heating power was reliably switched off due to the increased level of stray radiation. Moreover, ECRH bolometers with a slower response time in the launcher ports and an empty diagnostic port were used to estimate the stray radiation level in the ports. In the launcher ports it could be shown that the stray radiation could lead to an overheating of the bellows in long discharges. Possible counter measures are discussed.
Liquid-Assisted Femtosecond Laser Precision-Machining of Silica.
Cao, Xiao-Wen; Chen, Qi-Dai; Fan, Hua; Zhang, Lei; Juodkazis, Saulius; Sun, Hong-Bo
2018-04-28
We report a systematical study on the liquid assisted femtosecond laser machining of quartz plate in water and under different etching solutions. The ablation features in liquid showed a better structuring quality and improved resolution with 1/3~1/2 smaller features as compared with those made in air. It has been demonstrated that laser induced periodic structures are present to a lesser extent when laser processed in water solutions. The redistribution of oxygen revealed a strong surface modification, which is related to the etching selectivity of laser irradiated regions. Laser ablation in KOH and HF solution showed very different morphology, which relates to the evolution of laser induced plasma on the formation of micro/nano-features in liquid. This work extends laser precision fabrication of hard materials. The mechanism of strong absorption in the regions with permittivity (epsilon) near zero is discussed.
Laser milling of martensitic stainless steels using spiral trajectories
NASA Astrophysics Data System (ADS)
Romoli, L.; Tantussi, F.; Fuso, F.
2017-04-01
A laser beam with sub-picosecond pulse duration was driven in spiral trajectories to perform micro-milling of martensitic stainless steel. The geometry of the machined micro-grooves channels was investigated by a specifically conceived Scanning Probe Microscopy instrument and linked to laser parameters by using an experimental approach combining the beam energy distribution profile and the absorption phenomena in the material. Preliminary analysis shows that, despite the numerous parameters involved in the process, layer removal obtained by spiral trajectories, varying the radial overlap, allows for a controllable depth of cut combined to a flattening effect of surface roughness. Combining the developed machining strategy to a feed motion of the work stage, could represent a method to obtain three-dimensional structures with a resolution of few microns, with an areal roughness Sa below 100 nm.
Proof of the Feasibility of Coherent and Incoherent Schemes for Pumping a Gamma-Ray Laser
1989-07-01
compounds held in plastic vials or cylindrical planchettes . Foils and planchertes were exposed with their faces normal to the machine center- line. The...irradiation; foils and planchettes were counted with a solid NaI(TI) detector system and vials were again studied with the well detector. Samples...P to flat planchettes , and F to metallic foils. The self-absorption corrections represent the fraction of fluorescent photons which reach the
NASA Astrophysics Data System (ADS)
Jia, Xiaodong; Jin, Chao; Buzza, Matt; Di, Yuan; Siegel, David; Lee, Jay
2018-01-01
Successful applications of Diffusion Map (DM) in machine failure detection and diagnosis have been reported in several recent studies. DM provides an efficient way to visualize the high-dimensional, complex and nonlinear machine data, and thus suggests more knowledge about the machine under monitoring. In this paper, a DM based methodology named as DM-EVD is proposed for machine degradation assessment, abnormality detection and diagnosis in an online fashion. Several limitations and challenges of using DM for machine health monitoring have been analyzed and addressed. Based on the proposed DM-EVD, a deviation based methodology is then proposed to include more dimension reduction methods. In this work, the incorporation of Laplacian Eigen-map and Principal Component Analysis (PCA) are explored, and the latter algorithm is named as PCA-Dev and is validated in the case study. To show the successful application of the proposed methodology, case studies from diverse fields are presented and investigated in this work. Improved results are reported by benchmarking with other machine learning algorithms.
NASA Astrophysics Data System (ADS)
Hong, Haibo; Yin, Yuehong; Chen, Xing
2016-11-01
Despite the rapid development of computer science and information technology, an efficient human-machine integrated enterprise information system for designing complex mechatronic products is still not fully accomplished, partly because of the inharmonious communication among collaborators. Therefore, one challenge in human-machine integration is how to establish an appropriate knowledge management (KM) model to support integration and sharing of heterogeneous product knowledge. Aiming at the diversity of design knowledge, this article proposes an ontology-based model to reach an unambiguous and normative representation of knowledge. First, an ontology-based human-machine integrated design framework is described, then corresponding ontologies and sub-ontologies are established according to different purposes and scopes. Second, a similarity calculation-based ontology integration method composed of ontology mapping and ontology merging is introduced. The ontology searching-based knowledge sharing method is then developed. Finally, a case of human-machine integrated design of a large ultra-precision grinding machine is used to demonstrate the effectiveness of the method.
A Senior Project-Based Multiphase Motor Drive System Development
ERIC Educational Resources Information Center
Abdel-Khalik, Ayman S.; Massoud, Ahmed M.; Ahmed, Shehab
2016-01-01
Adjustable-speed drives based on multiphase motors are of significant interest for safety-critical applications that necessitate wide fault-tolerant capabilities and high system reliability. Although multiphase machines are based on the same conceptual theory as three-phase machines, most undergraduate electrical machines and electric drives…
Fuzzy support vector machine: an efficient rule-based classification technique for microarrays.
Hajiloo, Mohsen; Rabiee, Hamid R; Anooshahpour, Mahdi
2013-01-01
The abundance of gene expression microarray data has led to the development of machine learning algorithms applicable for tackling disease diagnosis, disease prognosis, and treatment selection problems. However, these algorithms often produce classifiers with weaknesses in terms of accuracy, robustness, and interpretability. This paper introduces fuzzy support vector machine which is a learning algorithm based on combination of fuzzy classifiers and kernel machines for microarray classification. Experimental results on public leukemia, prostate, and colon cancer datasets show that fuzzy support vector machine applied in combination with filter or wrapper feature selection methods develops a robust model with higher accuracy than the conventional microarray classification models such as support vector machine, artificial neural network, decision trees, k nearest neighbors, and diagonal linear discriminant analysis. Furthermore, the interpretable rule-base inferred from fuzzy support vector machine helps extracting biological knowledge from microarray data. Fuzzy support vector machine as a new classification model with high generalization power, robustness, and good interpretability seems to be a promising tool for gene expression microarray classification.
Cycle simulation of the low-temperature triple-effect absorption chiller with vapor compression unit
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kim, J.S.; Lee, H.
1999-07-01
The construction of a triple-effect absorption chiller machine using the lithium bromide-water solution as a working fluid is strongly limited by corrosion problems caused by the high generator temperature. In this work, three new cycles having the additional vapor compression units were suggested in order to lower the generator temperature of a triple-effect absorption chiller. Each new cycle has one compressor located at the different position which was used to elevate the pressure of the refrigerant vapor. Computer simulations were carried out in order to examine both the basic triple-effect cycle and three new cycles. All types of triple-effect absorptionmore » chiller cycles were found to be able to lower the temperature of high-temperature generator to the more favorable operation range. The COPs of three cycles calculated by considering the additional compressor works showed a small level of decrease or increase compared with that of the basic triple-effect cycle. Consequently, a low-temperature triple-effect absorption chiller can be possibly constructed by adapting one of three new cycles. A great advantage of these new cycles over the basic one is that the conventionally used lithium bromide-water solution can be successfully used as a working fluid without the danger of corrosion.« less
Influence of small particles inclusion on selective laser melting of Ti-6Al-4V powder
NASA Astrophysics Data System (ADS)
Gong, Haijun; Dilip, J. J. S.; Yang, Li; Teng, Chong; Stucker, Brent
2017-12-01
The particle size distribution and powder morphology of metallic powders have an important effect on powder bed fusion based additive manufacturing processes, such as selective laser melting (SLM). The process development and parameter optimization require a fundamental understanding of the influence of powder on SLM. This study introduces a pre-alloyed titanium alloy Ti-6Al-4V powder, which has a certain amount of small particles, for SLM. The influence of small particle inclusion is investigated through microscopy of surface topography, elemental and microstructural analysis, and mechanical testing, compared to the Ti-6Al-4V powder provided by SLM machine vendor. It is found that the small particles inclusion in Ti-6Al-4V powder has a noticeable effect on extra laser energy absorption, which may develop imperfections and deteriorate the SLM fatigue performance.
NASA Astrophysics Data System (ADS)
Kistenev, Yury V.; Borisov, Alexey V.; Titarenko, Maria A.; Baydik, Olga D.; Shapovalov, Alexander V.
2018-04-01
The ability to diagnose oral lichen planus (OLP) based on saliva analysis using THz time-domain spectroscopy and chemometrics is discussed. The study involved 30 patients (2 male and 28 female) with OLP. This group consisted of two subgroups with the erosive form of OLP (n = 15) and with the reticular and papular forms of OLP (n = 15). The control group consisted of six healthy volunteers (one male and five females) without inflammation in the mucous membrane in the oral cavity and without periodontitis. Principal component analysis was used to reveal informative features in the experimental data. The one-versus-one multiclass classifier using support vector machine binary classifiers was used. The two-stage classification approach using several absorption spectra scans for an individual saliva sample provided 100% accuracy of differential classification between OLP subgroups and control group.
Hole Quality Assessment in Drilling of Glass Microballoon/Epoxy Syntactic Foams
NASA Astrophysics Data System (ADS)
Ashrith, H. S.; Doddamani, Mrityunjay; Gaitonde, Vinayak; Gupta, Nikhil
2018-05-01
Syntactic foams reinforced with glass microballoons are used as alternatives for conventional materials in structural application of aircrafts and automobiles due to their unique properties such as light weight, high compressive strength, and low moisture absorption. Drilling is the most commonly used process of making holes for assembling structural components. In the present investigation, grey relation analysis (GRA) is used to optimize cutting speed, feed, drill diameter, and filler content to minimize cylindricity, circularity error, and damage factor. Experiments based on full factorial design are conducted using a vertical computer numerical control machine and tungsten carbide twist drills. GRA reveals that a combination of lower cutting speed, filler content, and drill diameter produces a good quality hole at optimum intermediate feed in drilling syntactic foams composites. GRA also shows that the drill diameter has a significant effect on the hole quality. Furthermore, damage on the hole exit side is analyzed using a scanning electron microscope.
A system framework of inter-enterprise machining quality control based on fractal theory
NASA Astrophysics Data System (ADS)
Zhao, Liping; Qin, Yongtao; Yao, Yiyong; Yan, Peng
2014-03-01
In order to meet the quality control requirement of dynamic and complicated product machining processes among enterprises, a system framework of inter-enterprise machining quality control based on fractal was proposed. In this system framework, the fractal-specific characteristic of inter-enterprise machining quality control function was analysed, and the model of inter-enterprise machining quality control was constructed by the nature of fractal structures. Furthermore, the goal-driven strategy of inter-enterprise quality control and the dynamic organisation strategy of inter-enterprise quality improvement were constructed by the characteristic analysis on this model. In addition, the architecture of inter-enterprise machining quality control based on fractal was established by means of Web service. Finally, a case study for application was presented. The result showed that the proposed method was available, and could provide guidance for quality control and support for product reliability in inter-enterprise machining processes.
Impact behaviour of Napier/polyester composites under different energy levels
NASA Astrophysics Data System (ADS)
Fahmi, I.; Majid, M. S. Abdul; Afendi, M.; Haslan, M.; Helmi E., A.; M. Haameem J., A.
2016-07-01
The effects of different energy levels on the impact behaviour of Napier fibre/polyester reinforced composites were investigated. Napier fibre was extracted using traditional water retting process to be utilized as reinforcing materials in polyester composite laminates. 25% fibre loading composite laminates were prepared and impacted at three different energy levels; 2.5,5 and 7.5 J using an instrumented drop weight impact testing machine (IMATEK IM10). The outcomes show that peak force and contact time increase with increased impact load. The energy absorption was then calculated from the force displacement curve. The results indicated that the energy absorption decreases with increasing energy levels of the impact. Impacted specimens were observed visually for fragmentation fracture using an optical camera to identify the failure mechanisms. Fracture fragmentation pattern from permanent dent to perforation with radial and circumferential was observed.
NASA Astrophysics Data System (ADS)
Zhou, Ming; Liu, Li-Peng; Dai, Qi-Xun; Pan, Chuan-Peng
2005-01-01
Two-photon absorption (TPA) is confined at the focus under tight-focusing conditions, which provides a novel concept for micro-fabrication using two-photon photo-polymerization in resin. The development of three-dimensional micro-fabrication by femtosecond laser was introduced at first, then the merits of femtosecond two-photon photo-polymerization was expatiated. Femtosecond laser direct scanning three-dimensional (3D) micro-fabrication system was set up and corresponding controlling software was developed. We demonstrated a fabrication of three-dimensional microstructures using photo-polymerization of resin by two-photon absorption. The precision of micro-machining and the spatial resolution reached 1um because of TPA. The dependence of fabricated line width to the micro-fabrication speed was investigated. Benzene ring, CHINA and layer-by-layer of log structures were fabricated in this 3D- micro-fabrication system as examples.
Numerical Simulation of Earth Pressure on Head Chamber of Shield Machine with FEM
DOE Office of Scientific and Technical Information (OSTI.GOV)
Li Shouju; Kang Chengang; Sun, Wei
2010-05-21
Model parameters of conditioned soils in head chamber of shield machine are determined based on tree-axial compression tests in laboratory. The loads acting on tunneling face are estimated according to static earth pressure principle. Based on Duncan-Chang nonlinear elastic constitutive model, the earth pressures on head chamber of shield machine are simulated in different aperture ratio cases for rotating cutterhead of shield machine. Relationship between pressure transportation factor and aperture ratio of shield machine is proposed by using aggression analysis.
Vane Pump Casing Machining of Dumpling Machine Based on CAD/CAM
NASA Astrophysics Data System (ADS)
Huang, Yusen; Li, Shilong; Li, Chengcheng; Yang, Zhen
Automatic dumpling forming machine is also called dumpling machine, which makes dumplings through mechanical motions. This paper adopts the stuffing delivery mechanism featuring the improved and specially-designed vane pump casing, which can contribute to the formation of dumplings. Its 3D modeling in Pro/E software, machining process planning, milling path optimization, simulation based on UG and compiling post program were introduced and verified. The results indicated that adoption of CAD/CAM offers firms the potential to pursue new innovative strategies.
NASA Astrophysics Data System (ADS)
Cheng, Kai; Niu, Zhi-Chao; Wang, Robin C.; Rakowski, Richard; Bateman, Richard
2017-09-01
Smart machining has tremendous potential and is becoming one of new generation high value precision manufacturing technologies in line with the advance of Industry 4.0 concepts. This paper presents some innovative design concepts and, in particular, the development of four types of smart cutting tools, including a force-based smart cutting tool, a temperature-based internally-cooled cutting tool, a fast tool servo (FTS) and smart collets for ultraprecision and micro manufacturing purposes. Implementation and application perspectives of these smart cutting tools are explored and discussed particularly for smart machining against a number of industrial application requirements. They are contamination-free machining, machining of tool-wear-prone Si-based infra-red devices and medical applications, high speed micro milling and micro drilling, etc. Furthermore, implementation techniques are presented focusing on: (a) plug-and-produce design principle and the associated smart control algorithms, (b) piezoelectric film and surface acoustic wave transducers to measure cutting forces in process, (c) critical cutting temperature control in real-time machining, (d) in-process calibration through machining trials, (e) FE-based design and analysis of smart cutting tools, and (f) application exemplars on adaptive smart machining.
NASA Astrophysics Data System (ADS)
alhilman, Judi
2017-12-01
In the production line process of the printing office, the reliability of the printing machine plays a very important role, if the machine fail it can disrupt production target so that the company will suffer huge financial loss. One method to calculate the financial loss cause by machine failure is use the Cost of Unreliability(COUR) method. COUR method works based on down time machine and costs associated with unreliability data. Based on the calculation of COUR method, so the sum of cost due to unreliability printing machine during active repair time and downtime is 1003,747.00.
Jian, Yulin; Huang, Daoyu; Yan, Jia; Lu, Kun; Huang, Ying; Wen, Tailai; Zeng, Tanyue; Zhong, Shijie; Xie, Qilong
2017-06-19
A novel classification model, named the quantum-behaved particle swarm optimization (QPSO)-based weighted multiple kernel extreme learning machine (QWMK-ELM), is proposed in this paper. Experimental validation is carried out with two different electronic nose (e-nose) datasets. Being different from the existing multiple kernel extreme learning machine (MK-ELM) algorithms, the combination coefficients of base kernels are regarded as external parameters of single-hidden layer feedforward neural networks (SLFNs). The combination coefficients of base kernels, the model parameters of each base kernel, and the regularization parameter are optimized by QPSO simultaneously before implementing the kernel extreme learning machine (KELM) with the composite kernel function. Four types of common single kernel functions (Gaussian kernel, polynomial kernel, sigmoid kernel, and wavelet kernel) are utilized to constitute different composite kernel functions. Moreover, the method is also compared with other existing classification methods: extreme learning machine (ELM), kernel extreme learning machine (KELM), k-nearest neighbors (KNN), support vector machine (SVM), multi-layer perceptron (MLP), radical basis function neural network (RBFNN), and probabilistic neural network (PNN). The results have demonstrated that the proposed QWMK-ELM outperforms the aforementioned methods, not only in precision, but also in efficiency for gas classification.
Development of flat-plate solar plate collector: Evaporator
NASA Astrophysics Data System (ADS)
Abramzon, B.; Yaron, I.
1981-11-01
In the present study the thermal performance of a flat plate solar collector is analyzed theoretically for the case in which the working fluid may undergo a phase change within the tubes of the collector. In addition to the common domestic applications, such a collector - evaporator may be used as a generator of vapors for the production of mechanical or electrical energy, e.g., solar water pumps, solar power stations, etc., as well as for solar - powered absorption refrigeration machines, distillation installations, etc.
Optical Properties of Zinc Selenide Grown Using Molecular Beam Deposition Techniques
1989-06-01
studied were grown using a standard MBE machine with insitu diagnostics. The ZnSe material used for growing the samples is highly pure polycrystalline...width of the interference maxima n can be found from equation (1). Beyond 550 nm absorption is varying rapidly and this will cause Tmax to vary...nonlinearity Is utilized - such as in an optically bistable switch. It is known from previous work on ZnSe grown on GaAs 113] that the material begins growing
Ma, Xiao H; Jia, Jia; Zhu, Feng; Xue, Ying; Li, Ze R; Chen, Yu Z
2009-05-01
Machine learning methods have been explored as ligand-based virtual screening tools for facilitating drug lead discovery. These methods predict compounds of specific pharmacodynamic, pharmacokinetic or toxicological properties based on their structure-derived structural and physicochemical properties. Increasing attention has been directed at these methods because of their capability in predicting compounds of diverse structures and complex structure-activity relationships without requiring the knowledge of target 3D structure. This article reviews current progresses in using machine learning methods for virtual screening of pharmacodynamically active compounds from large compound libraries, and analyzes and compares the reported performances of machine learning tools with those of structure-based and other ligand-based (such as pharmacophore and clustering) virtual screening methods. The feasibility to improve the performance of machine learning methods in screening large libraries is discussed.
Investigation of gastric cancers in nude mice using X-ray in-line phase contrast imaging.
Tao, Qiang; Luo, Shuqian
2014-07-24
This paper is to report the new imaging of gastric cancers without the use of imaging agents. Both gastric normal regions and gastric cancer regions can be distinguished by using the principal component analysis (PCA) based on the gray level co-occurrence matrix (GLCM). Human gastric cancer BGC823 cells were implanted into the stomachs of nude mice. Then, 3, 5, 7, 9 or 11 days after cancer cells implantation, the nude mice were sacrificed and their stomachs were removed. X-ray in-line phase contrast imaging (XILPCI), an X-ray phase contrast imaging method, has greater soft tissue contrast than traditional absorption radiography and generates higher-resolution images. The gastric specimens were imaged by an XILPCIs' charge coupled device (CCD) of 9 μm image resolution. The PCA of the projective images' region of interests (ROIs) based on GLCM were extracted to discriminate gastric normal regions and gastric cancer regions. Different stages of gastric cancers were classified by using support vector machines (SVMs). The X-ray in-line phase contrast images of nude mice gastric specimens clearly show the gastric architectures and the details of the early gastric cancers. The phase contrast computed tomography (CT) images of nude mice gastric cancer specimens are better than the traditional absorption CT images without the use of imaging agents. The results of the PCA of the texture parameters based on GLCM of normal regions is (F1+F2) >8.5, but those of cancer regions is (F1+F2) <8.5. The classification accuracy is 83.3% that classifying gastric specimens into different stages using SVMs. This is a very preliminary feasibility study. With further researches, XILPCI could become a noninvasive method for future the early detection of gastric cancers or medical researches.
Cell classification using big data analytics plus time stretch imaging (Conference Presentation)
NASA Astrophysics Data System (ADS)
Jalali, Bahram; Chen, Claire L.; Mahjoubfar, Ata
2016-09-01
We show that blood cells can be classified with high accuracy and high throughput by combining machine learning with time stretch quantitative phase imaging. Our diagnostic system captures quantitative phase images in a flow microscope at millions of frames per second and extracts multiple biophysical features from individual cells including morphological characteristics, light absorption and scattering parameters, and protein concentration. These parameters form a hyperdimensional feature space in which supervised learning and cell classification is performed. We show binary classification of T-cells against colon cancer cells, as well classification of algae cell strains with high and low lipid content. The label-free screening averts the negative impact of staining reagents on cellular viability or cell signaling. The combination of time stretch machine vision and learning offers unprecedented cell analysis capabilities for cancer diagnostics, drug development and liquid biopsy for personalized genomics.
NASA Astrophysics Data System (ADS)
Byers, J. M.; Doctor, K.
2017-12-01
A common application of the satellite and airborne acquired hyperspectral imagery in the visible and NIR spectrum is the assessment of vegetation. Various absorption features of plants related to both water and chlorophyll content can be used to measure the vigor and access to underlying water sources of the vegetation. The typical strategy is to form hand-crafted features from the hyperspectral data cube by selecting two wavelengths to form difference or ratio images in the pixel space. The new image attempts to provide greater contrast for some feature of the vegetation. The Normalized Difference Vegetation Index (NDVI) is a widely used example formed from the ratio of differences and sums at two different wavelengths. There are dozens of these indices that are ostensibly formed using insights about the underlying physics of the spectral absorption with claims to efficacy in representing various properties of vegetation. In the language of machine learning these vegetation indices are features that can be used as a useful data representation within an algorithm. In this work we use a powerful approach from machine learning, probabilistic graphical models (PGM), to balance the competing needs of using existing hydrological classifications of terrain while finding statistically reliable features within hyperspectral data for identifying the generative process of the data. The algorithm in its simplest form is called a Naïve Bayes (NB) classifier and can be constructed in a data-driven estimation procedure of the conditional probability distributions that form the PGM. The Naïve Bayes model assumes that all vegetation indices (VI) are independent of one another given the hydrological class label. We seek to test its validity in a pilot study of detecting subsurface water flow pathways from VI. A more sophisticated PGM will also be explored called a tree-augmented NB that accounts for the probabilistic dependence between VI features. This methodology provides a general approach for classifying hydrological structures from hyperspectral data.
Support vector machine in machine condition monitoring and fault diagnosis
NASA Astrophysics Data System (ADS)
Widodo, Achmad; Yang, Bo-Suk
2007-08-01
Recently, the issue of machine condition monitoring and fault diagnosis as a part of maintenance system became global due to the potential advantages to be gained from reduced maintenance costs, improved productivity and increased machine availability. This paper presents a survey of machine condition monitoring and fault diagnosis using support vector machine (SVM). It attempts to summarize and review the recent research and developments of SVM in machine condition monitoring and diagnosis. Numerous methods have been developed based on intelligent systems such as artificial neural network, fuzzy expert system, condition-based reasoning, random forest, etc. However, the use of SVM for machine condition monitoring and fault diagnosis is still rare. SVM has excellent performance in generalization so it can produce high accuracy in classification for machine condition monitoring and diagnosis. Until 2006, the use of SVM in machine condition monitoring and fault diagnosis is tending to develop towards expertise orientation and problem-oriented domain. Finally, the ability to continually change and obtain a novel idea for machine condition monitoring and fault diagnosis using SVM will be future works.
Applications of Machine Learning and Rule Induction,
1995-02-15
An important area of application for machine learning is in automating the acquisition of knowledge bases required for expert systems. In this paper...we review the major paradigms for machine learning , including neural networks, instance-based methods, genetic learning, rule induction, and analytic
Simulation and Community-Based Instruction of Vending Machines with Time Delay.
ERIC Educational Resources Information Center
Browder, Diane M.; And Others
1988-01-01
The study evaluated the use of simulated instruction on vending machine use as an adjunct to community-based instruction with two moderately retarded children. Results showed concurrent acquisition of the vending machine skills across trained and untrained sites. (Author/DB)
Fuzzy logic controller optimization
Sepe, Jr., Raymond B; Miller, John Michael
2004-03-23
A method is provided for optimizing a rotating induction machine system fuzzy logic controller. The fuzzy logic controller has at least one input and at least one output. Each input accepts a machine system operating parameter. Each output produces at least one machine system control parameter. The fuzzy logic controller generates each output based on at least one input and on fuzzy logic decision parameters. Optimization begins by obtaining a set of data relating each control parameter to at least one operating parameter for each machine operating region. A model is constructed for each machine operating region based on the machine operating region data obtained. The fuzzy logic controller is simulated with at least one created model in a feedback loop from a fuzzy logic output to a fuzzy logic input. Fuzzy logic decision parameters are optimized based on the simulation.
Alumina additions may improve the damage tolerance of soft machined zirconia-based ceramics.
Oilo, Marit; Tvinnereim, Helene M; Gjerdet, Nils Roar
2011-01-01
The aim of this study was to evaluate the damage tolerance of different zirconia-based materials. Bars of one hard machined and one soft machined dental zirconia and an experimental 95% zirconia 5% alumina ceramic were subjected to 100,000 stress cycles (n = 10), indented to provoke cracks on the tensile stress side (n = 10), and left untreated as controls (n = 10). The experimental material demonstrated a higher relative damage tolerance, with a 40% reduction compared to 68% for the hard machined zirconia and 84% for the soft machined zirconia.
Parodi, Stefano; Manneschi, Chiara; Verda, Damiano; Ferrari, Enrico; Muselli, Marco
2018-03-01
This study evaluates the performance of a set of machine learning techniques in predicting the prognosis of Hodgkin's lymphoma using clinical factors and gene expression data. Analysed samples from 130 Hodgkin's lymphoma patients included a small set of clinical variables and more than 54,000 gene features. Machine learning classifiers included three black-box algorithms ( k-nearest neighbour, Artificial Neural Network, and Support Vector Machine) and two methods based on intelligible rules (Decision Tree and the innovative Logic Learning Machine method). Support Vector Machine clearly outperformed any of the other methods. Among the two rule-based algorithms, Logic Learning Machine performed better and identified a set of simple intelligible rules based on a combination of clinical variables and gene expressions. Decision Tree identified a non-coding gene ( XIST) involved in the early phases of X chromosome inactivation that was overexpressed in females and in non-relapsed patients. XIST expression might be responsible for the better prognosis of female Hodgkin's lymphoma patients.
Improving the reliability of inverter-based welding machines
DOE Office of Scientific and Technical Information (OSTI.GOV)
Schiedermayer, M.
1997-02-01
Although inverter-based welding power sources have been available since the late 1980s, many people hesitated to purchase them because of reliability issues. Unfortunately, their hesitancy had a basis, until now. Recent improvements give some inverters a reliability level that approaches that of traditional, transformer-based industrial welding machines, which have a failure rate of about 1%. Acceptance of inverter-based welding machines is important because, for many welding applications, they provide capabilities that solid-state, transformer-based machines cannot deliver. These advantages include enhanced pulsed gas metal arc welding (GMAW-P), lightweight portability, an ultrastable arc, and energy efficiency--all while producing highly aesthetic weld beadsmore » and delivering multiprocess capabilities.« less
Lohbauer, Ulrich; Belli, Renan; Cune, Marco S; Schepke, Ulf
2017-01-01
Today, a substantial part of the dental crown production uses computer-aided design and computer-aided manufacturing (CAD/CAM) technology. A recent step in restorative dentistry is the replacement of natural tooth structure with pre-polymerized and machined resin-based methacrylic polymers. Recently, a new CAD/CAM composite was launched for the crown indication in the load-bearing area, but the clinical reality forced the manufacturer to withdraw this specific indication. In parallel, a randomized clinical trial of CAD/CAM composite crowns luted on zirconia implant abutments revealed a high incidence of failure within the first year of service. Fractured crowns of this clinical trial were retrieved and submitted to a fractographic examination. The aim of the case series presented in this article was to identify failure reasons for a new type of CAD/CAM composite crown material (Lava Ultimate; 3M Oral Care, St. Paul, Minnesota, USA) via fractographic examinations and analytical assessment of luting surfaces and water absorption behavior. As a result, the debonding of the composite crowns from the zirconia implant abutments was identified as the central reason for failure. The adhesive interface was found the weakest link. A lack of silica at the zirconia surface certainly has compromised the bonding potential of the adhesive system from the beginning. Additionally, the hydrolytic stress released from swelling of the resin-based crown (water absorption) and transfer to the luting interface further added to the interfacial stress and most probably contributed to a great extend to the debonding failure. PMID:29204275
Lohbauer, Ulrich; Belli, Renan; Cune, Marco S; Schepke, Ulf
2017-01-01
Today, a substantial part of the dental crown production uses computer-aided design and computer-aided manufacturing (CAD/CAM) technology. A recent step in restorative dentistry is the replacement of natural tooth structure with pre-polymerized and machined resin-based methacrylic polymers. Recently, a new CAD/CAM composite was launched for the crown indication in the load-bearing area, but the clinical reality forced the manufacturer to withdraw this specific indication. In parallel, a randomized clinical trial of CAD/CAM composite crowns luted on zirconia implant abutments revealed a high incidence of failure within the first year of service. Fractured crowns of this clinical trial were retrieved and submitted to a fractographic examination. The aim of the case series presented in this article was to identify failure reasons for a new type of CAD/CAM composite crown material (Lava Ultimate; 3M Oral Care, St. Paul, Minnesota, USA) via fractographic examinations and analytical assessment of luting surfaces and water absorption behavior. As a result, the debonding of the composite crowns from the zirconia implant abutments was identified as the central reason for failure. The adhesive interface was found the weakest link. A lack of silica at the zirconia surface certainly has compromised the bonding potential of the adhesive system from the beginning. Additionally, the hydrolytic stress released from swelling of the resin-based crown (water absorption) and transfer to the luting interface further added to the interfacial stress and most probably contributed to a great extend to the debonding failure.
Diestelmeier, B W; Rudert, M J; Tochigi, Y; Baer, T E; Fredericks, D C; Brown, T D
2014-06-01
For systematic laboratory studies of bone fractures in general and intra-articular fractures in particular, it is often necessary to control for injury severity. Quantitatively, a parameter of primary interest in that regard is the energy absorbed during the injury event. For this purpose, a novel technique has been developed to measure energy absorption in experimental impaction. The specific application is for fracture insult to porcine hock (tibiotalar) joints in vivo, for which illustrative intra-operative data are reported. The instrumentation allowed for the measurement of the delivered kinetic energy and of the energy passed through the specimen during impaction. The energy absorbed by the specimen was calculated as the difference between those two values. A foam specimen validation study was first performed to compare the energy absorption measurements from the pendulum instrumentation versus the work of indentation performed by an MTS machine. Following validation, the pendulum apparatus was used to measure the energy absorbed during intra-articular fractures created in 14 minipig hock joints in vivo. The foam validation study showed close correspondence between the pendulum-measured energy absorption and MTS-performed work of indentation. In the survival animal series, the energy delivered ranged from 31.5 to 48.3 Js (41.3±4.0, mean±s.d.) and the proportion of energy absorbed to energy delivered ranged from 44.2% to 64.7% (53.6%±4.5%). The foam validation results support the reliability of the energy absorption measure provided by the instrumented pendulum system. Given that a very substantial proportion of delivered energy passed--unabsorbed--through the specimens, the energy absorption measure provided by this novel technique arguably provides better characterization of injury severity than is provided simply by energy delivery.
Jian, Yulin; Huang, Daoyu; Yan, Jia; Lu, Kun; Huang, Ying; Wen, Tailai; Zeng, Tanyue; Zhong, Shijie; Xie, Qilong
2017-01-01
A novel classification model, named the quantum-behaved particle swarm optimization (QPSO)-based weighted multiple kernel extreme learning machine (QWMK-ELM), is proposed in this paper. Experimental validation is carried out with two different electronic nose (e-nose) datasets. Being different from the existing multiple kernel extreme learning machine (MK-ELM) algorithms, the combination coefficients of base kernels are regarded as external parameters of single-hidden layer feedforward neural networks (SLFNs). The combination coefficients of base kernels, the model parameters of each base kernel, and the regularization parameter are optimized by QPSO simultaneously before implementing the kernel extreme learning machine (KELM) with the composite kernel function. Four types of common single kernel functions (Gaussian kernel, polynomial kernel, sigmoid kernel, and wavelet kernel) are utilized to constitute different composite kernel functions. Moreover, the method is also compared with other existing classification methods: extreme learning machine (ELM), kernel extreme learning machine (KELM), k-nearest neighbors (KNN), support vector machine (SVM), multi-layer perceptron (MLP), radical basis function neural network (RBFNN), and probabilistic neural network (PNN). The results have demonstrated that the proposed QWMK-ELM outperforms the aforementioned methods, not only in precision, but also in efficiency for gas classification. PMID:28629202
ERIC Educational Resources Information Center
Hepburn, Larry; Shin, Masako
This document, one of eight in a multi-cultural competency-based vocational/technical curricula series, is on machine trades. This program is designed to run 36 weeks and cover 6 instructional areas: use of measuring tools; benchwork/tool bit grinding; lathe work; milling work; precision grinding; and combination machine work. A duty-task index…
Barua, Shaibal; Begum, Shahina; Ahmed, Mobyen Uddin
2015-01-01
Machine learning algorithms play an important role in computer science research. Recent advancement in sensor data collection in clinical sciences lead to a complex, heterogeneous data processing, and analysis for patient diagnosis and prognosis. Diagnosis and treatment of patients based on manual analysis of these sensor data are difficult and time consuming. Therefore, development of Knowledge-based systems to support clinicians in decision-making is important. However, it is necessary to perform experimental work to compare performances of different machine learning methods to help to select appropriate method for a specific characteristic of data sets. This paper compares classification performance of three popular machine learning methods i.e., case-based reasoning, neutral networks and support vector machine to diagnose stress of vehicle drivers using finger temperature and heart rate variability. The experimental results show that case-based reasoning outperforms other two methods in terms of classification accuracy. Case-based reasoning has achieved 80% and 86% accuracy to classify stress using finger temperature and heart rate variability. On contrary, both neural network and support vector machine have achieved less than 80% accuracy by using both physiological signals.
Impact behaviour of Napier/polyester composites under different energy levels
DOE Office of Scientific and Technical Information (OSTI.GOV)
Fahmi, I., E-mail: fahmi-unimap@yahoo.com; Majid, M. S. Abdul, E-mail: shukry@unimap.edu.my; Afendi, M., E-mail: afendirojan@unimap.edu.my
2016-07-19
The effects of different energy levels on the impact behaviour of Napier fibre/polyester reinforced composites were investigated. Napier fibre was extracted using traditional water retting process to be utilized as reinforcing materials in polyester composite laminates. 25% fibre loading composite laminates were prepared and impacted at three different energy levels; 2.5,5 and 7.5 J using an instrumented drop weight impact testing machine (IMATEK IM10). The outcomes show that peak force and contact time increase with increased impact load. The energy absorption was then calculated from the force displacement curve. The results indicated that the energy absorption decreases with increasing energymore » levels of the impact. Impacted specimens were observed visually for fragmentation fracture using an optical camera to identify the failure mechanisms. Fracture fragmentation pattern from permanent dent to perforation with radial and circumferential was observed.« less
High frame-rate MR-guided near-infrared tomography system to monitor breast hemodynamics
NASA Astrophysics Data System (ADS)
Li, Zhiqiu; Jiang, Shudong; Krishnaswamy, Venkataramanan; Davis, Scott C.; Srinivasan, Subhadra; Paulsen, Keith D.; Pogue, Brian W.
2011-02-01
A near-infrared (NIR) tomography system with spectral-encoded sources at two wavelength bands was built to quantify the temporal contrast at 20 Hz bandwidth, while imaging breast tissue. The NIR system was integrated with a magnetic resonance (MR) machine through a custom breast coil interface, and both NIR data and MR images were acquired simultaneously. MR images provided breast tissue structural information for NIR reconstruction. Acquisition of finger pulse oximeter (PO) plethysmogram was synchronized with the NIR system in the experiment to offer a frequency-locked reference. The recovered absorption coefficients of the breast at two wavelengths showed identical temporal frequency as the PO output, proving this multi-modality design can recover the small pulsatile variation of absorption property in breast tissue related to the heartbeat. And it also showed the system's ability on novel contrast imaging of fast flow signals in deep tissue.
Standard measurement procedures for the characterization of fs-laser optical components
NASA Astrophysics Data System (ADS)
Starke, Kai; Ristau, Detlev; Welling, Herbert
2003-05-01
Ultra-short pulse laser systems are considered as promising tools in the fields of precise micro-machining and medicine applications. In the course of the development of reliable table top laser systems, a rapid growth of ultra-short pulse applications could be observed during the recent years. The key for improving the performance of high power laser systems is the quality of the optical components concerning spectral characteristics, optical losses and the power handling capability. In the field of ultra-short pulses, standard measurement procedures in quality management have to be validated in respect to effects induced by the extremely high peak power densities. The present work, which is embedded in the EUREKA-project CHOCLAB II, is predominantly concentrated on measuring the multiple-pulse LIDT (ISO 11254-2) in the fs-regime. A measurement facility based on a Ti:Sapphire-CPA system was developed to investigate the damage behavior of optical components. The set-up was supplied with an improved pulse energy detector discriminating the influence of pulse-to-pulse energy fluctuations on the incidence of damage. Aditionally, a laser-calorimetric measurement facility determining the absorption (ISO 11551) utilizing a fs-Ti:Sapphire laser was accomplished. The investigation for different pulse durations between 130 fs and 1 ps revealed a drastic increase of absorption in titania coatings for ultra-short pulses.
Knowledge-based load leveling and task allocation in human-machine systems
NASA Technical Reports Server (NTRS)
Chignell, M. H.; Hancock, P. A.
1986-01-01
Conventional human-machine systems use task allocation policies which are based on the premise of a flexible human operator. This individual is most often required to compensate for and augment the capabilities of the machine. The development of artificial intelligence and improved technologies have allowed for a wider range of task allocation strategies. In response to these issues a Knowledge Based Adaptive Mechanism (KBAM) is proposed for assigning tasks to human and machine in real time, using a load leveling policy. This mechanism employs an online workload assessment and compensation system which is responsive to variations in load through an intelligent interface. This interface consists of a loading strategy reasoner which has access to information about the current status of the human-machine system as well as a database of admissible human/machine loading strategies. Difficulties standing in the way of successful implementation of the load leveling strategy are examined.
NASA Technical Reports Server (NTRS)
Simon, F. F.
1975-01-01
The use of a solar simulator for performance determination permits collector testing under standard conditions of wind, ambient temperature, flow rate and sun. The performance results determined with the simulator have been found to be in good agreement with outdoor performance results. The measured thermal efficiency and evaluation of 23 collectors are reported which differ according to absorber material (copper, aluminum, steel), absorber coating (nonselective black paint, selective copper oxide, selective black nickel, selective black chrome), type of glazing material (glass, Tedlar, Lexan, antireflection glass), the use of honeycomb material and the use of vacuum to prevent thermal convection losses. The collectors were given performance rankings based on noon-hour solar conditions and all-day solar conditions. The determination with the simulator of an all-day collector performance was made possible by tests at different incident angles. The solar performance rankings were made based on whether the collector is to be used for pool heating, hot water, absorption air conditioning, heating, or for a solar Rankine machine.
Effect of iron status on iron absorption in different habitual meals in young south Indian women.
Kalasuramath, Suneeta; Kurpad, Anura V; Thankachan, Prashanth
2013-02-01
Iron deficiency (ID) affects a large number of women in India. An inverse relationship exists between iron (Fe) status and Fe absorption. Dietary inhibitory and enhancing factors exert a profound influence on bioavailability of Fe. Although the current recommended dietary allowance (RDA) for Fe is based on 8 per cent bioavailability, it is not clear if this holds good for the usual highly inhibitory Indian diet matrix. This study was aimed to determine Fe absorption from several habitually consumed south Indian food and to evaluate the interaction of Fe status with absorption. Four Fe absorption studies were performed on 60 apparently healthy young women, aged 18-35 years. Based on blood biochemistry, 45 of them were ID and 15 were iron replete (IR). The habitual meals assessed were rice, millet and wheat based meals in the ID subjects and rice based meal alone in the IR subjects. Each subject received the test meal labelled with 3 mg of ⁵⁷Fe and Fe absorption was measured based on erythrocyte incorporation of isotope label 14 days following administration. Mean fractional Fe absorption from the rice, wheat and millet based meals in the ID subjects were 8.3, 11.2 and 4.6 per cent, respectively. Fe absorption from the rice-based meals was 2.5 per cent in IR subjects. Fe absorption is dictated by Fe status from low bioavailability meals. Millet based meals have the lowest bioavailability, while the rice and wheat based meals had moderate to good bioavailability. In millet based meals, it is prudent to consider ways to improve Fe absorption.
Machine vision for digital microfluidics
NASA Astrophysics Data System (ADS)
Shin, Yong-Jun; Lee, Jeong-Bong
2010-01-01
Machine vision is widely used in an industrial environment today. It can perform various tasks, such as inspecting and controlling production processes, that may require humanlike intelligence. The importance of imaging technology for biological research or medical diagnosis is greater than ever. For example, fluorescent reporter imaging enables scientists to study the dynamics of gene networks with high spatial and temporal resolution. Such high-throughput imaging is increasingly demanding the use of machine vision for real-time analysis and control. Digital microfluidics is a relatively new technology with expectations of becoming a true lab-on-a-chip platform. Utilizing digital microfluidics, only small amounts of biological samples are required and the experimental procedures can be automatically controlled. There is a strong need for the development of a digital microfluidics system integrated with machine vision for innovative biological research today. In this paper, we show how machine vision can be applied to digital microfluidics by demonstrating two applications: machine vision-based measurement of the kinetics of biomolecular interactions and machine vision-based droplet motion control. It is expected that digital microfluidics-based machine vision system will add intelligence and automation to high-throughput biological imaging in the future.
Ahmed, Shiek S. S. J.; Ramakrishnan, V.
2012-01-01
Background Poor oral bioavailability is an important parameter accounting for the failure of the drug candidates. Approximately, 50% of developing drugs fail because of unfavorable oral bioavailability. In silico prediction of oral bioavailability (%F) based on physiochemical properties are highly needed. Although many computational models have been developed to predict oral bioavailability, their accuracy remains low with a significant number of false positives. In this study, we present an oral bioavailability model based on systems biological approach, using a machine learning algorithm coupled with an optimal discriminative set of physiochemical properties. Results The models were developed based on computationally derived 247 physicochemical descriptors from 2279 molecules, among which 969, 605 and 705 molecules were corresponds to oral bioavailability, intestinal absorption (HIA) and caco-2 permeability data set, respectively. The partial least squares discriminate analysis showed 49 descriptors of HIA and 50 descriptors of caco-2 are the major contributing descriptors in classifying into groups. Of these descriptors, 47 descriptors were commonly associated to HIA and caco-2, which suggests to play a vital role in classifying oral bioavailability. To determine the best machine learning algorithm, 21 classifiers were compared using a bioavailability data set of 969 molecules with 47 descriptors. Each molecule in the data set was represented by a set of 47 physiochemical properties with the functional relevance labeled as (+bioavailability/−bioavailability) to indicate good-bioavailability/poor-bioavailability molecules. The best-performing algorithm was the logistic algorithm. The correlation based feature selection (CFS) algorithm was implemented, which confirms that these 47 descriptors are the fundamental descriptors for oral bioavailability prediction. Conclusion The logistic algorithm with 47 selected descriptors correctly predicted the oral bioavailability, with a predictive accuracy of more than 71%. Overall, the method captures the fundamental molecular descriptors, that can be used as an entity to facilitate prediction of oral bioavailability. PMID:22815781
Ahmed, Shiek S S J; Ramakrishnan, V
2012-01-01
Poor oral bioavailability is an important parameter accounting for the failure of the drug candidates. Approximately, 50% of developing drugs fail because of unfavorable oral bioavailability. In silico prediction of oral bioavailability (%F) based on physiochemical properties are highly needed. Although many computational models have been developed to predict oral bioavailability, their accuracy remains low with a significant number of false positives. In this study, we present an oral bioavailability model based on systems biological approach, using a machine learning algorithm coupled with an optimal discriminative set of physiochemical properties. The models were developed based on computationally derived 247 physicochemical descriptors from 2279 molecules, among which 969, 605 and 705 molecules were corresponds to oral bioavailability, intestinal absorption (HIA) and caco-2 permeability data set, respectively. The partial least squares discriminate analysis showed 49 descriptors of HIA and 50 descriptors of caco-2 are the major contributing descriptors in classifying into groups. Of these descriptors, 47 descriptors were commonly associated to HIA and caco-2, which suggests to play a vital role in classifying oral bioavailability. To determine the best machine learning algorithm, 21 classifiers were compared using a bioavailability data set of 969 molecules with 47 descriptors. Each molecule in the data set was represented by a set of 47 physiochemical properties with the functional relevance labeled as (+bioavailability/-bioavailability) to indicate good-bioavailability/poor-bioavailability molecules. The best-performing algorithm was the logistic algorithm. The correlation based feature selection (CFS) algorithm was implemented, which confirms that these 47 descriptors are the fundamental descriptors for oral bioavailability prediction. The logistic algorithm with 47 selected descriptors correctly predicted the oral bioavailability, with a predictive accuracy of more than 71%. Overall, the method captures the fundamental molecular descriptors, that can be used as an entity to facilitate prediction of oral bioavailability.
A survey of machine readable data bases
NASA Technical Reports Server (NTRS)
Matlock, P.
1981-01-01
Forty-two of the machine readable data bases available to the technologist and researcher in the natural sciences and engineering are described and compared with the data bases and date base services offered by NASA.
The dynamic analysis of drum roll lathe for machining of rollers
NASA Astrophysics Data System (ADS)
Qiao, Zheng; Wu, Dongxu; Wang, Bo; Li, Guo; Wang, Huiming; Ding, Fei
2014-08-01
An ultra-precision machine tool for machining of the roller has been designed and assembled, and due to the obvious impact which dynamic characteristic of machine tool has on the quality of microstructures on the roller surface, the dynamic characteristic of the existing machine tool is analyzed in this paper, so is the influence of circumstance that a large scale and slender roller is fixed in the machine on dynamic characteristic of the machine tool. At first, finite element model of the machine tool is built and simplified, and based on that, the paper carries on with the finite element mode analysis and gets the natural frequency and shaking type of four steps of the machine tool. According to the above model analysis results, the weak stiffness systems of machine tool can be further improved and the reasonable bandwidth of control system of the machine tool can be designed. In the end, considering the shock which is caused by Z axis as a result of fast positioning frequently to feeding system and cutting tool, transient analysis is conducted by means of ANSYS analysis in this paper. Based on the results of transient analysis, the vibration regularity of key components of machine tool and its impact on cutting process are explored respectively.
NASA Astrophysics Data System (ADS)
Budi Harja, Herman; Prakosa, Tri; Raharno, Sri; Yuwana Martawirya, Yatna; Nurhadi, Indra; Setyo Nogroho, Alamsyah
2018-03-01
The production characteristic of job-shop industry at which products have wide variety but small amounts causes every machine tool will be shared to conduct production process with dynamic load. Its dynamic condition operation directly affects machine tools component reliability. Hence, determination of maintenance schedule for every component should be calculated based on actual usage of machine tools component. This paper describes study on development of monitoring system to obtaining information about each CNC machine tool component usage in real time approached by component grouping based on its operation phase. A special device has been developed for monitoring machine tool component usage by utilizing usage phase activity data taken from certain electronics components within CNC machine. The components are adaptor, servo driver and spindle driver, as well as some additional components such as microcontroller and relays. The obtained data are utilized for detecting machine utilization phases such as power on state, machine ready state or spindle running state. Experimental result have shown that the developed CNC machine tool monitoring system is capable of obtaining phase information of machine tool usage as well as its duration and displays the information at the user interface application.
Method and system for controlling a synchronous machine over full operating range
Walters, James E.; Gunawan, Fani S.; Xue, Yanhong
2002-01-01
System and method for controlling a synchronous machine are provided. The method allows for calculating a stator voltage index. The method further allows for relating the magnitude of the stator voltage index against a threshold voltage value. An offset signal is generated based on the results of the relating step. A respective state of operation of the machine is determined. The offset signal is processed based on the respective state of the machine.
A Typology of UK Slot Machine Gamblers: A Longitudinal Observational and Interview Study
ERIC Educational Resources Information Center
Griffiths, Mark D.
2011-01-01
Slot machine gambling is a popular leisure activity worldwide yet there has been very little research into different types of slot machine gamblers. Earlier typologies of slot machine gamblers have only concentrated on adolescents in arcade environments. This study presents a new typology of slot machine players based on over 1000 h of participant…
Relative Kerf and Sawing Variation Values for Some Hardwood Sawing Machines
Philip H. Steele; Michael W. Wade; Steven H. Bullard; Philip A. Araman
1992-01-01
Information on the conversion efficiency of sawing machines is important to those involved in the management, maintenance, and design of sawmills. Little information on the conversion characteristics of hardwood sawing machines has been available. This study, based on 266 studies of 6 machine types, provides an analysis of the machine characteristics of kerf width,...
On Intelligent Design and Planning Method of Process Route Based on Gun Breech Machining Process
NASA Astrophysics Data System (ADS)
Hongzhi, Zhao; Jian, Zhang
2018-03-01
The paper states an approach of intelligent design and planning of process route based on gun breech machining process, against several problems, such as complex machining process of gun breech, tedious route design and long period of its traditional unmanageable process route. Based on gun breech machining process, intelligent design and planning system of process route are developed by virtue of DEST and VC++. The system includes two functional modules--process route intelligent design and its planning. The process route intelligent design module, through the analysis of gun breech machining process, summarizes breech process knowledge so as to complete the design of knowledge base and inference engine. And then gun breech process route intelligently output. On the basis of intelligent route design module, the final process route is made, edited and managed in the process route planning module.
Li, Wu; Hu, Bing; Wang, Ming-wei
2014-12-01
In the present paper, the terahertz time-domain spectroscopy (THz-TDS) identification model of borneol based on principal component analysis (PCA) and support vector machine (SVM) was established. As one Chinese common agent, borneol needs a rapid, simple and accurate detection and identification method for its different source and being easily confused in the pharmaceutical and trade links. In order to assure the quality of borneol product and guard the consumer's right, quickly, efficiently and correctly identifying borneol has significant meaning to the production and transaction of borneol. Terahertz time-domain spectroscopy is a new spectroscopy approach to characterize material using terahertz pulse. The absorption terahertz spectra of blumea camphor, borneol camphor and synthetic borneol were measured in the range of 0.2 to 2 THz with the transmission THz-TDS. The PCA scores of 2D plots (PC1 X PC2) and 3D plots (PC1 X PC2 X PC3) of three kinds of borneol samples were obtained through PCA analysis, and both of them have good clustering effect on the 3 different kinds of borneol. The value matrix of the first 10 principal components (PCs) was used to replace the original spectrum data, and the 60 samples of the three kinds of borneol were trained and then the unknown 60 samples were identified. Four kinds of support vector machine model of different kernel functions were set up in this way. Results show that the accuracy of identification and classification of SVM RBF kernel function for three kinds of borneol is 100%, and we selected the SVM with the radial basis kernel function to establish the borneol identification model, in addition, in the noisy case, the classification accuracy rates of four SVM kernel function are above 85%, and this indicates that SVM has strong generalization ability. This study shows that PCA with SVM method of borneol terahertz spectroscopy has good classification and identification effects, and provides a new method for species identification of borneol in Chinese medicine.
LHCb experience with running jobs in virtual machines
NASA Astrophysics Data System (ADS)
McNab, A.; Stagni, F.; Luzzi, C.
2015-12-01
The LHCb experiment has been running production jobs in virtual machines since 2013 as part of its DIRAC-based infrastructure. We describe the architecture of these virtual machines and the steps taken to replicate the WLCG worker node environment expected by user and production jobs. This relies on the uCernVM system for providing root images for virtual machines. We use the CernVM-FS distributed filesystem to supply the root partition files, the LHCb software stack, and the bootstrapping scripts necessary to configure the virtual machines for us. Using this approach, we have been able to minimise the amount of contextualisation which must be provided by the virtual machine managers. We explain the process by which the virtual machine is able to receive payload jobs submitted to DIRAC by users and production managers, and how this differs from payloads executed within conventional DIRAC pilot jobs on batch queue based sites. We describe our operational experiences in running production on VM based sites managed using Vcycle/OpenStack, Vac, and HTCondor Vacuum. Finally we show how our use of these resources is monitored using Ganglia and DIRAC.
Zeng, Xueqiang; Luo, Gang
2017-12-01
Machine learning is broadly used for clinical data analysis. Before training a model, a machine learning algorithm must be selected. Also, the values of one or more model parameters termed hyper-parameters must be set. Selecting algorithms and hyper-parameter values requires advanced machine learning knowledge and many labor-intensive manual iterations. To lower the bar to machine learning, miscellaneous automatic selection methods for algorithms and/or hyper-parameter values have been proposed. Existing automatic selection methods are inefficient on large data sets. This poses a challenge for using machine learning in the clinical big data era. To address the challenge, this paper presents progressive sampling-based Bayesian optimization, an efficient and automatic selection method for both algorithms and hyper-parameter values. We report an implementation of the method. We show that compared to a state of the art automatic selection method, our method can significantly reduce search time, classification error rate, and standard deviation of error rate due to randomization. This is major progress towards enabling fast turnaround in identifying high-quality solutions required by many machine learning-based clinical data analysis tasks.
Calibrating the HISA temperature: Measuring the temperature of the Riegel-Crutcher cloud
NASA Astrophysics Data System (ADS)
Dénes, H.; McClure-Griffiths, N. M.; Dickey, J. M.; Dawson, J. R.; Murray, C. E.
2018-06-01
H I self absorption (HISA) clouds are clumps of cold neutral hydrogen (H I) visible in front of warm background gas, which makes them ideal places to study the properties of the cold atomic component of the interstellar medium (ISM). The Riegel-Crutcher (R-C) cloud is the most striking HISA feature in the Galaxy. It is one of the closest HISA clouds to us and is located in the direction of the Galactic Centre, which provides a bright background. High-resolution interferometric measurements have revealed the filamentary structure of this cloud, however it is difficult to accurately determine the temperature and the density of the gas without optical depth measurements. In this paper we present new H I absorption observations with the Australia Telescope Compact Array (ATCA) against 46 continuum sources behind the Riegel-Crutcher cloud to directly measure the optical depth of the cloud. We decompose the complex H I absorption spectra into Gaussian components using an automated machine learning algorithm. We find 300 Gaussian components, from which 67 are associated with the R-C cloud (0 < vLSR < 10 km s-1, FWHM <10 km s-1). Combining the new H I absorption data with H I emission data from previous surveys we calculate the spin temperature and find it to be between 20 and 80 K. Our measurements uncover a temperature gradient across the cloud with spin temperatures decreasing towards positive Galactic latitudes. We also find three new OH absorption lines associated with the cloud, which support the presence of molecular gas.
Improving Energy Efficiency in CNC Machining
NASA Astrophysics Data System (ADS)
Pavanaskar, Sushrut S.
We present our work on analyzing and improving the energy efficiency of multi-axis CNC milling process. Due to the differences in energy consumption behavior, we treat 3- and 5-axis CNC machines separately in our work. For 3-axis CNC machines, we first propose an energy model that estimates the energy requirement for machining a component on a specified 3-axis CNC milling machine. Our model makes machine-specific predictions of energy requirements while also considering the geometric aspects of the machining toolpath. Our model - and the associated software tool - facilitate direct comparison of various alternative toolpath strategies based on their energy-consumption performance. Further, we identify key factors in toolpath planning that affect energy consumption in CNC machining. We then use this knowledge to propose and demonstrate a novel toolpath planning strategy that may be used to generate new toolpaths that are inherently energy-efficient, inspired by research on digital micrography -- a form of computational art. For 5-axis CNC machines, the process planning problem consists of several sub-problems that researchers have traditionally solved separately to obtain an approximate solution. After illustrating the need to solve all sub-problems simultaneously for a truly optimal solution, we propose a unified formulation based on configuration space theory. We apply our formulation to solve a problem variant that retains key characteristics of the full problem but has lower dimensionality, allowing visualization in 2D. Given the complexity of the full 5-axis toolpath planning problem, our unified formulation represents an important step towards obtaining a truly optimal solution. With this work on the two types of CNC machines, we demonstrate that without changing the current infrastructure or business practices, machine-specific, geometry-based, customized toolpath planning can save energy in CNC machining.
Competency-Based Education Curriculum for Machine Shop. Teacher's Guide.
ERIC Educational Resources Information Center
Associated Educational Consultants, Inc., Pittsburgh, PA.
This teacher's guide is designed to accompany the machine shop competency-based education curriculum for secondary students in West Virginia. It has been developed to facilitate use of the curriculum by instructors of machine shop programs. The teacher's guide contains the following material: an explanation of the curriculum and suggested usage; a…
NASA Astrophysics Data System (ADS)
Yang, Xiaokang; Petrov, Yuri; Ceccherini, Francesco; Koehn, Alf; Galeotti, Laura; Dettrick, Sean; Binderbauer, Michl
2017-10-01
Numerous efforts have been made at Tri-Alpha Energy (TAE) to theoretically explore the physics of microwave electron heating in field-reversed configuration (FRC) plasmas. For the fixed 2D profiles of plasma density and temperature for both electrons and thermal ions and equilibrium field of the C-2U machine, simulations with GENRAY-C ray-tracing code have been conducted for the ratios of ω/ωci[D] in the range of 6 - 20. Launch angles and antenna radial and axial positions have been optimized in order to simultaneously achieve good wave penetration into the core of FRC plasmas and efficient power damping on electrons. It is found that in an optimal regime, single pass absorption efficiency is 100% and most of the power is deposited inside the separatrix of FRC plasmas, with power damping efficiency of about 72% on electrons and less than 19% on ions. Calculations have clearly demonstrated that substantial power absorption on electrons is mainly attributed to high beta enhancement of magnetic pumping; complete power damping occurs before Landau damping has a significant effect on power absorption.
Prediction of drug synergy in cancer using ensemble-based machine learning techniques
NASA Astrophysics Data System (ADS)
Singh, Harpreet; Rana, Prashant Singh; Singh, Urvinder
2018-04-01
Drug synergy prediction plays a significant role in the medical field for inhibiting specific cancer agents. It can be developed as a pre-processing tool for therapeutic successes. Examination of different drug-drug interaction can be done by drug synergy score. It needs efficient regression-based machine learning approaches to minimize the prediction errors. Numerous machine learning techniques such as neural networks, support vector machines, random forests, LASSO, Elastic Nets, etc., have been used in the past to realize requirement as mentioned above. However, these techniques individually do not provide significant accuracy in drug synergy score. Therefore, the primary objective of this paper is to design a neuro-fuzzy-based ensembling approach. To achieve this, nine well-known machine learning techniques have been implemented by considering the drug synergy data. Based on the accuracy of each model, four techniques with high accuracy are selected to develop ensemble-based machine learning model. These models are Random forest, Fuzzy Rules Using Genetic Cooperative-Competitive Learning method (GFS.GCCL), Adaptive-Network-Based Fuzzy Inference System (ANFIS) and Dynamic Evolving Neural-Fuzzy Inference System method (DENFIS). Ensembling is achieved by evaluating the biased weighted aggregation (i.e. adding more weights to the model with a higher prediction score) of predicted data by selected models. The proposed and existing machine learning techniques have been evaluated on drug synergy score data. The comparative analysis reveals that the proposed method outperforms others in terms of accuracy, root mean square error and coefficient of correlation.
Machine-learning in grading of gliomas based on multi-parametric magnetic resonance imaging at 3T.
Citak-Er, Fusun; Firat, Zeynep; Kovanlikaya, Ilhami; Ture, Ugur; Ozturk-Isik, Esin
2018-06-15
The objective of this study was to assess the contribution of multi-parametric (mp) magnetic resonance imaging (MRI) quantitative features in the machine learning-based grading of gliomas with a multi-region-of-interests approach. Forty-three patients who were newly diagnosed as having a glioma were included in this study. The patients were scanned prior to any therapy using a standard brain tumor magnetic resonance (MR) imaging protocol that included T1 and T2-weighted, diffusion-weighted, diffusion tensor, MR perfusion and MR spectroscopic imaging. Three different regions-of-interest were drawn for each subject to encompass tumor, immediate tumor periphery, and distant peritumoral edema/normal. The normalized mp-MRI features were used to build machine-learning models for differentiating low-grade gliomas (WHO grades I and II) from high grades (WHO grades III and IV). In order to assess the contribution of regional mp-MRI quantitative features to the classification models, a support vector machine-based recursive feature elimination method was applied prior to classification. A machine-learning model based on support vector machine algorithm with linear kernel achieved an accuracy of 93.0%, a specificity of 86.7%, and a sensitivity of 96.4% for the grading of gliomas using ten-fold cross validation based on the proposed subset of the mp-MRI features. In this study, machine-learning based on multiregional and multi-parametric MRI data has proven to be an important tool in grading glial tumors accurately even in this limited patient population. Future studies are needed to investigate the use of machine learning algorithms for brain tumor classification in a larger patient cohort. Copyright © 2018. Published by Elsevier Ltd.
Nano Mechanical Machining Using AFM Probe
NASA Astrophysics Data System (ADS)
Mostofa, Md. Golam
Complex miniaturized components with high form accuracy will play key roles in the future development of many products, as they provide portability, disposability, lower material consumption in production, low power consumption during operation, lower sample requirements for testing, and higher heat transfer due to their very high surface-to-volume ratio. Given the high market demand for such micro and nano featured components, different manufacturing methods have been developed for their fabrication. Some of the common technologies in micro/nano fabrication are photolithography, electron beam lithography, X-ray lithography and other semiconductor processing techniques. Although these methods are capable of fabricating micro/nano structures with a resolution of less than a few nanometers, some of the shortcomings associated with these methods, such as high production costs for customized products, limited material choices, necessitate the development of other fabricating techniques. Micro/nano mechanical machining, such an atomic force microscope (AFM) probe based nano fabrication, has, therefore, been used to overcome some the major restrictions of the traditional processes. This technique removes material from the workpiece by engaging micro/nano size cutting tool (i.e. AFM probe) and is applicable on a wider range of materials compared to the photolithographic process. In spite of the unique benefits of nano mechanical machining, there are also some challenges with this technique, since the scale is reduced, such as size effects, burr formations, chip adhesions, fragility of tools and tool wear. Moreover, AFM based machining does not have any rotational movement, which makes fabrication of 3D features more difficult. Thus, vibration-assisted machining is introduced into AFM probe based nano mechanical machining to overcome the limitations associated with the conventional AFM probe based scratching method. Vibration-assisted machining reduced the cutting forces and burr formations through intermittent cutting. Combining the AFM probe based machining with vibration-assisted machining enhanced nano mechanical machining processes by improving the accuracy, productivity and surface finishes. In this study, several scratching tests are performed with a single crystal diamond AFM probe to investigate the cutting characteristics and model the ploughing cutting forces. Calibration of the probe for lateral force measurements, which is essential, is also extended through the force balance method. Furthermore, vibration-assisted machining system is developed and applied to fabricate different materials to overcome some of the limitations of the AFM probe based single point nano mechanical machining. The novelty of this study includes the application of vibration-assisted AFM probe based nano scale machining to fabricate micro/nano scale features, calibration of an AFM by considering different factors, and the investigation of the nano scale material removal process from a different perspective.
View north of west gallery of inside machine shop 36; ...
View north of west gallery of inside machine shop 36; the gallery housed turret, engine and toolroom lathes, small milling machines and drill presses used for machining small parts. - Naval Base Philadelphia-Philadelphia Naval Shipyard, Structure Shop, League Island, Philadelphia, Philadelphia County, PA
Development of a low energy micro sheet forming machine
NASA Astrophysics Data System (ADS)
Razali, A. R.; Ann, C. T.; Shariff, H. M.; Kasim, N. I.; Musa, M. A.; Ahmad, A. F.
2017-10-01
It is expected that with the miniaturization of materials being processed, energy consumption is also being `miniaturized' proportionally. The focus of this study was to design a low energy micro-sheet-forming machine for thin sheet metal application and fabricate a low direct current powered micro-sheet-forming machine. A prototype of low energy system for a micro-sheet-forming machine which includes mechanical and electronic elements was developed. The machine was tested for its performance in terms of natural frequency, punching forces, punching speed and capability, energy consumption (single punch and frequency-time based). Based on the experiments, the machine can do 600 stroke per minute and the process is unaffected by the machine's natural frequency. It was also found that sub-Joule of power was required for a single stroke of punching/blanking process. Up to 100micron thick carbon steel shim was successfully tested and punched. It concludes that low power forming machine is feasible to be developed and be used to replace high powered machineries to form micro-products/parts.
Scientific bases of human-machine communication by voice.
Schafer, R W
1995-01-01
The scientific bases for human-machine communication by voice are in the fields of psychology, linguistics, acoustics, signal processing, computer science, and integrated circuit technology. The purpose of this paper is to highlight the basic scientific and technological issues in human-machine communication by voice and to point out areas of future research opportunity. The discussion is organized around the following major issues in implementing human-machine voice communication systems: (i) hardware/software implementation of the system, (ii) speech synthesis for voice output, (iii) speech recognition and understanding for voice input, and (iv) usability factors related to how humans interact with machines. PMID:7479802
Articulated, Performance-Based Instruction Objectives Guide for Machine Shop Technology.
ERIC Educational Resources Information Center
Henderson, William Edward, Jr., Ed.
This articulation guide contains 21 units of instruction for two years of machine shop. The objectives of the program are to provide the student with the basic terminology and fundamental knowledge and skills in machining (year 1) and to teach him/her to set up and operate machine tools and make or repair metal parts, tools, and machines (year 2).…
The influence of machining condition and cutting tool wear on surface roughness of AISI 4340 steel
NASA Astrophysics Data System (ADS)
Natasha, A. R.; Ghani, J. A.; Che Haron, C. H.; Syarif, J.
2018-01-01
Sustainable machining by using cryogenic coolant as the cutting fluid has been proven to enhance some machining outputs. The main objective of the current work was to investigate the influence of machining conditions; dry and cryogenic, as well as the cutting tool wear on the machined surface roughness of AISI 4340 steel. The experimental tests were performed using chemical vapor deposition (CVD) coated carbide inserts. The value of machined surface roughness were measured at 3 cutting intervals; beginning, middle, and end of the cutting based on the readings of the tool flank wear. The results revealed that cryogenic turning had the greatest influence on surface roughness when machined at lower cutting speed and higher feed rate. Meanwhile, the cutting tool wear was also found to influence the surface roughness, either improving it or deteriorating it, based on the severity and the mechanism of the flank wear.
Entanglement-Based Machine Learning on a Quantum Computer
NASA Astrophysics Data System (ADS)
Cai, X.-D.; Wu, D.; Su, Z.-E.; Chen, M.-C.; Wang, X.-L.; Li, Li; Liu, N.-L.; Lu, C.-Y.; Pan, J.-W.
2015-03-01
Machine learning, a branch of artificial intelligence, learns from previous experience to optimize performance, which is ubiquitous in various fields such as computer sciences, financial analysis, robotics, and bioinformatics. A challenge is that machine learning with the rapidly growing "big data" could become intractable for classical computers. Recently, quantum machine learning algorithms [Lloyd, Mohseni, and Rebentrost, arXiv.1307.0411] were proposed which could offer an exponential speedup over classical algorithms. Here, we report the first experimental entanglement-based classification of two-, four-, and eight-dimensional vectors to different clusters using a small-scale photonic quantum computer, which are then used to implement supervised and unsupervised machine learning. The results demonstrate the working principle of using quantum computers to manipulate and classify high-dimensional vectors, the core mathematical routine in machine learning. The method can, in principle, be scaled to larger numbers of qubits, and may provide a new route to accelerate machine learning.
Machine learning-based methods for prediction of linear B-cell epitopes.
Wang, Hsin-Wei; Pai, Tun-Wen
2014-01-01
B-cell epitope prediction facilitates immunologists in designing peptide-based vaccine, diagnostic test, disease prevention, treatment, and antibody production. In comparison with T-cell epitope prediction, the performance of variable length B-cell epitope prediction is still yet to be satisfied. Fortunately, due to increasingly available verified epitope databases, bioinformaticians could adopt machine learning-based algorithms on all curated data to design an improved prediction tool for biomedical researchers. Here, we have reviewed related epitope prediction papers, especially those for linear B-cell epitope prediction. It should be noticed that a combination of selected propensity scales and statistics of epitope residues with machine learning-based tools formulated a general way for constructing linear B-cell epitope prediction systems. It is also observed from most of the comparison results that the kernel method of support vector machine (SVM) classifier outperformed other machine learning-based approaches. Hence, in this chapter, except reviewing recently published papers, we have introduced the fundamentals of B-cell epitope and SVM techniques. In addition, an example of linear B-cell prediction system based on physicochemical features and amino acid combinations is illustrated in details.
Zhang, A; Critchley, S; Monsour, P A
2016-12-01
The aim of the present study was to assess the current adoption of cone beam computed tomography (CBCT) and panoramic radiography (PR) machines across Australia. Information regarding registered CBCT and PR machines was obtained from radiation regulators across Australia. The number of X-ray machines was correlated with the population size, the number of dentists, and the gross state product (GSP) per capita, to determine the best fitting regression model(s). In 2014, there were 232 CBCT and 1681 PR machines registered in Australia. Based on absolute counts, Queensland had the largest number of CBCT and PR machines whereas the Northern Territory had the smallest number. However, when based on accessibility in terms of the population size and the number of dentists, the Australian Capital Territory had the most CBCT machines and Western Australia had the most PR machines. The number of X-ray machines correlated strongly with both the population size and the number of dentists, but not with the GSP per capita. In 2014, the ratio of PR to CBCT machines was approximately 7:1. Projected increases in either the population size or the number of dentists could positively impact on the adoption of PR and CBCT machines in Australia. © 2016 Australian Dental Association.
Deng, Li; Wang, Guohua; Yu, Suihuai
2016-01-01
In order to consider the psychological cognitive characteristics affecting operating comfort and realize the automatic layout design, cognitive ergonomics and GA-ACA (genetic algorithm and ant colony algorithm) were introduced into the layout design of human-machine interaction interface. First, from the perspective of cognitive psychology, according to the information processing process, the cognitive model of human-machine interaction interface was established. Then, the human cognitive characteristics were analyzed, and the layout principles of human-machine interaction interface were summarized as the constraints in layout design. Again, the expression form of fitness function, pheromone, and heuristic information for the layout optimization of cabin was studied. The layout design model of human-machine interaction interface was established based on GA-ACA. At last, a layout design system was developed based on this model. For validation, the human-machine interaction interface layout design of drilling rig control room was taken as an example, and the optimization result showed the feasibility and effectiveness of the proposed method.
Deng, Li; Wang, Guohua; Yu, Suihuai
2016-01-01
In order to consider the psychological cognitive characteristics affecting operating comfort and realize the automatic layout design, cognitive ergonomics and GA-ACA (genetic algorithm and ant colony algorithm) were introduced into the layout design of human-machine interaction interface. First, from the perspective of cognitive psychology, according to the information processing process, the cognitive model of human-machine interaction interface was established. Then, the human cognitive characteristics were analyzed, and the layout principles of human-machine interaction interface were summarized as the constraints in layout design. Again, the expression form of fitness function, pheromone, and heuristic information for the layout optimization of cabin was studied. The layout design model of human-machine interaction interface was established based on GA-ACA. At last, a layout design system was developed based on this model. For validation, the human-machine interaction interface layout design of drilling rig control room was taken as an example, and the optimization result showed the feasibility and effectiveness of the proposed method. PMID:26884745
Metalworking and machining fluids
Erdemir, Ali; Sykora, Frank; Dorbeck, Mark
2010-10-12
Improved boron-based metal working and machining fluids. Boric acid and boron-based additives that, when mixed with certain carrier fluids, such as water, cellulose and/or cellulose derivatives, polyhydric alcohol, polyalkylene glycol, polyvinyl alcohol, starch, dextrin, in solid and/or solvated forms result in improved metalworking and machining of metallic work pieces. Fluids manufactured with boric acid or boron-based additives effectively reduce friction, prevent galling and severe wear problems on cutting and forming tools.
Association Rule-based Predictive Model for Machine Failure in Industrial Internet of Things
NASA Astrophysics Data System (ADS)
Kwon, Jung-Hyok; Lee, Sol-Bee; Park, Jaehoon; Kim, Eui-Jik
2017-09-01
This paper proposes an association rule-based predictive model for machine failure in industrial Internet of things (IIoT), which can accurately predict the machine failure in real manufacturing environment by investigating the relationship between the cause and type of machine failure. To develop the predictive model, we consider three major steps: 1) binarization, 2) rule creation, 3) visualization. The binarization step translates item values in a dataset into one or zero, then the rule creation step creates association rules as IF-THEN structures using the Lattice model and Apriori algorithm. Finally, the created rules are visualized in various ways for users’ understanding. An experimental implementation was conducted using R Studio version 3.3.2. The results show that the proposed predictive model realistically predicts machine failure based on association rules.
Quantum neural network based machine translator for Hindi to English.
Narayan, Ravi; Singh, V P; Chakraverty, S
2014-01-01
This paper presents the machine learning based machine translation system for Hindi to English, which learns the semantically correct corpus. The quantum neural based pattern recognizer is used to recognize and learn the pattern of corpus, using the information of part of speech of individual word in the corpus, like a human. The system performs the machine translation using its knowledge gained during the learning by inputting the pair of sentences of Devnagri-Hindi and English. To analyze the effectiveness of the proposed approach, 2600 sentences have been evaluated during simulation and evaluation. The accuracy achieved on BLEU score is 0.7502, on NIST score is 6.5773, on ROUGE-L score is 0.9233, and on METEOR score is 0.5456, which is significantly higher in comparison with Google Translation and Bing Translation for Hindi to English Machine Translation.
National Aspects of Creating and Using MARC/RECON Records.
ERIC Educational Resources Information Center
Rather, John C., Ed.; Avram, Henriette D., Ed.
The Retrospective Conversion (RECON) Working Task Force investigated the problems of converting retrospective catalog records to machine readable form. The major conclusions and recommendations of the Task Force cover five areas: the level of machine-readable records, conversion of other machine-readable data bases, a machine-readable National…
Permutation parity machines for neural cryptography.
Reyes, Oscar Mauricio; Zimmermann, Karl-Heinz
2010-06-01
Recently, synchronization was proved for permutation parity machines, multilayer feed-forward neural networks proposed as a binary variant of the tree parity machines. This ability was already used in the case of tree parity machines to introduce a key-exchange protocol. In this paper, a protocol based on permutation parity machines is proposed and its performance against common attacks (simple, geometric, majority and genetic) is studied.
Permutation parity machines for neural cryptography
DOE Office of Scientific and Technical Information (OSTI.GOV)
Reyes, Oscar Mauricio; Escuela de Ingenieria Electrica, Electronica y Telecomunicaciones, Universidad Industrial de Santander, Bucaramanga; Zimmermann, Karl-Heinz
2010-06-15
Recently, synchronization was proved for permutation parity machines, multilayer feed-forward neural networks proposed as a binary variant of the tree parity machines. This ability was already used in the case of tree parity machines to introduce a key-exchange protocol. In this paper, a protocol based on permutation parity machines is proposed and its performance against common attacks (simple, geometric, majority and genetic) is studied.
NASA Astrophysics Data System (ADS)
Schille, Joerg; Schneider, Lutz; Streek, André; Kloetzer, Sascha; Loeschner, Udo
2016-03-01
In this paper, high-throughput ultrashort pulse laser machining is investigated on various industrial grade metals (Aluminium, Copper, Stainless steel) and Al2O3 ceramic at unprecedented processing speeds. This is achieved by using a high pulse repetition frequency picosecond laser with maximum average output power of 270 W in conjunction with a unique, in-house developed two-axis polygon scanner. Initially, different concepts of polygon scanners are engineered and tested to find out the optimal architecture for ultrafast and precision laser beam scanning. Remarkable 1,000 m/s scan speed is achieved on the substrate, and thanks to the resulting low pulse overlap, thermal accumulation and plasma absorption effects are avoided at up to 20 MHz pulse repetition frequencies. In order to identify optimum processing conditions for efficient high-average power laser machining, the depths of cavities produced under varied parameter settings are analyzed and, from the results obtained, the characteristic removal values are specified. The maximum removal rate is achieved as high as 27.8 mm3/min for Aluminium, 21.4 mm3/min for Copper, 15.3 mm3/min for Stainless steel and 129.1 mm3/min for Al2O3 when full available laser power is irradiated at optimum pulse repetition frequency.
NASA Astrophysics Data System (ADS)
Momin, Md. Abdul; Kondo, Naoshi; Kuramoto, Makoto; Ogawa, Yuichi; Shigi, Tomoo
2011-06-01
Research was conducted to acquire knowledge of the ultraviolet and visible spectrums from 300 -800 nm of some common varieties of Japanese citrus, to investigate the best wave-lengths for fluorescence excitation and the resulting fluorescence wave-lengths and to provide a scientific background for the best quality fluorescent imaging technique for detecting surface defects of citrus. A Hitachi U-4000 PC-based microprocessor controlled spectrophotometer was used to measure the absorption spectrum and a Hitachi F-4500 spectrophotometer was used for the fluorescence and excitation spectrums. We analyzed the spectrums and the selected varieties of citrus were categorized into four groups of known fluorescence level, namely strong, medium, weak and no fluorescence.The level of fluorescence of each variety was also examined by using machine vision system. We found that around 340-380 nm LEDs or UV lamps are appropriate as lighting devices for acquiring the best quality fluorescent image of the citrus varieties to examine their fluorescence intensity. Therefore an image acquisition device was constructed with three different lighting panels with UV LED at peak 365 nm, Blacklight blue lamps (BLB) peak at 350 nm and UV-B lamps at peak 306 nm. The results from fluorescent images also revealed that the findings of the measured spectrums worked properly and can be used for practical applications such as for detecting rotten, injured or damaged parts of a wide variety of citrus.
NASA Technical Reports Server (NTRS)
Malakar, Nabin K.; Lary, D. L.; Moore, A.; Gencaga, D.; Roscoe, B.; Albayrak, Arif; Petrenko, Maksym; Wei, Jennifer
2012-01-01
Air quality information is increasingly becoming a public health concern, since some of the aerosol particles pose harmful effects to peoples health. One widely available metric of aerosol abundance is the aerosol optical depth (AOD). The AOD is the integrated light extinction coefficient over a vertical atmospheric column of unit cross section, which represents the extent to which the aerosols in that vertical profile prevent the transmission of light by absorption or scattering. The comparison between the AOD measured from the ground-based Aerosol Robotic Network (AERONET) system and the satellite MODIS instruments at 550 nm shows that there is a bias between the two data products. We performed a comprehensive analysis exploring possible factors which may be contributing to the inter-instrumental bias between MODIS and AERONET. The analysis used several measured variables, including the MODIS AOD, as input in order to train a neural network in regression mode to predict the AERONET AOD values. This not only allowed us to obtain an estimate, but also allowed us to infer the optimal sets of variables that played an important role in the prediction. In addition, we applied machine learning to infer the global abundance of ground level PM2.5 from the AOD data and other ancillary satellite and meteorology products. This research is part of our goal to provide air quality information, which can also be useful for global epidemiology studies.
NASA Astrophysics Data System (ADS)
Pathak, Jaideep; Wikner, Alexander; Fussell, Rebeckah; Chandra, Sarthak; Hunt, Brian R.; Girvan, Michelle; Ott, Edward
2018-04-01
A model-based approach to forecasting chaotic dynamical systems utilizes knowledge of the mechanistic processes governing the dynamics to build an approximate mathematical model of the system. In contrast, machine learning techniques have demonstrated promising results for forecasting chaotic systems purely from past time series measurements of system state variables (training data), without prior knowledge of the system dynamics. The motivation for this paper is the potential of machine learning for filling in the gaps in our underlying mechanistic knowledge that cause widely-used knowledge-based models to be inaccurate. Thus, we here propose a general method that leverages the advantages of these two approaches by combining a knowledge-based model and a machine learning technique to build a hybrid forecasting scheme. Potential applications for such an approach are numerous (e.g., improving weather forecasting). We demonstrate and test the utility of this approach using a particular illustrative version of a machine learning known as reservoir computing, and we apply the resulting hybrid forecaster to a low-dimensional chaotic system, as well as to a high-dimensional spatiotemporal chaotic system. These tests yield extremely promising results in that our hybrid technique is able to accurately predict for a much longer period of time than either its machine-learning component or its model-based component alone.
Barrington, Luke; Turnbull, Douglas; Lanckriet, Gert
2012-01-01
Searching for relevant content in a massive amount of multimedia information is facilitated by accurately annotating each image, video, or song with a large number of relevant semantic keywords, or tags. We introduce game-powered machine learning, an integrated approach to annotating multimedia content that combines the effectiveness of human computation, through online games, with the scalability of machine learning. We investigate this framework for labeling music. First, a socially-oriented music annotation game called Herd It collects reliable music annotations based on the “wisdom of the crowds.” Second, these annotated examples are used to train a supervised machine learning system. Third, the machine learning system actively directs the annotation games to collect new data that will most benefit future model iterations. Once trained, the system can automatically annotate a corpus of music much larger than what could be labeled using human computation alone. Automatically annotated songs can be retrieved based on their semantic relevance to text-based queries (e.g., “funky jazz with saxophone,” “spooky electronica,” etc.). Based on the results presented in this paper, we find that actively coupling annotation games with machine learning provides a reliable and scalable approach to making searchable massive amounts of multimedia data. PMID:22460786
Game-powered machine learning.
Barrington, Luke; Turnbull, Douglas; Lanckriet, Gert
2012-04-24
Searching for relevant content in a massive amount of multimedia information is facilitated by accurately annotating each image, video, or song with a large number of relevant semantic keywords, or tags. We introduce game-powered machine learning, an integrated approach to annotating multimedia content that combines the effectiveness of human computation, through online games, with the scalability of machine learning. We investigate this framework for labeling music. First, a socially-oriented music annotation game called Herd It collects reliable music annotations based on the "wisdom of the crowds." Second, these annotated examples are used to train a supervised machine learning system. Third, the machine learning system actively directs the annotation games to collect new data that will most benefit future model iterations. Once trained, the system can automatically annotate a corpus of music much larger than what could be labeled using human computation alone. Automatically annotated songs can be retrieved based on their semantic relevance to text-based queries (e.g., "funky jazz with saxophone," "spooky electronica," etc.). Based on the results presented in this paper, we find that actively coupling annotation games with machine learning provides a reliable and scalable approach to making searchable massive amounts of multimedia data.
Research on bearing fault diagnosis of large machinery based on mathematical morphology
NASA Astrophysics Data System (ADS)
Wang, Yu
2018-04-01
To study the automatic diagnosis of large machinery fault based on support vector machine, combining the four common faults of the large machinery, the support vector machine is used to classify and identify the fault. The extracted feature vectors are entered. The feature vector is trained and identified by multi - classification method. The optimal parameters of the support vector machine are searched by trial and error method and cross validation method. Then, the support vector machine is compared with BP neural network. The results show that the support vector machines are short in time and high in classification accuracy. It is more suitable for the research of fault diagnosis in large machinery. Therefore, it can be concluded that the training speed of support vector machines (SVM) is fast and the performance is good.
AC Loss Analysis of MgB2-Based Fully Superconducting Machines
NASA Astrophysics Data System (ADS)
Feddersen, M.; Haran, K. S.; Berg, F.
2017-12-01
Superconducting electric machines have shown potential for significant increase in power density, making them attractive for size and weight sensitive applications such as offshore wind generation, marine propulsion, and hybrid-electric aircraft propulsion. Superconductors exhibit no loss under dc conditions, though ac current and field produce considerable losses due to hysteresis, eddy currents, and coupling mechanisms. For this reason, many present machines are designed to be partially superconducting, meaning that the dc field components are superconducting while the ac armature coils are conventional conductors. Fully superconducting designs can provide increases in power density with significantly higher armature current; however, a good estimate of ac losses is required to determine the feasibility under the machines intended operating conditions. This paper aims to characterize the expected losses in a fully superconducting machine targeted towards aircraft, based on an actively-shielded, partially superconducting machine from prior work. Various factors are examined such as magnet strength, operating frequency, and machine load to produce a model for the loss in the superconducting components of the machine. This model is then used to optimize the design of the machine for minimal ac loss while maximizing power density. Important observations from the study are discussed.
Optimal quantum cloning based on the maximin principle by using a priori information
NASA Astrophysics Data System (ADS)
Kang, Peng; Dai, Hong-Yi; Wei, Jia-Hua; Zhang, Ming
2016-10-01
We propose an optimal 1 →2 quantum cloning method based on the maximin principle by making full use of a priori information of amplitude and phase about the general cloned qubit input set, which is a simply connected region enclosed by a "longitude-latitude grid" on the Bloch sphere. Theoretically, the fidelity of the optimal quantum cloning machine derived from this method is the largest in terms of the maximin principle compared with that of any other machine. The problem solving is an optimization process that involves six unknown complex variables, six vectors in an uncertain-dimensional complex vector space, and four equality constraints. Moreover, by restricting the structure of the quantum cloning machine, the optimization problem is simplified as a three-real-parameter suboptimization problem with only one equality constraint. We obtain the explicit formula for a suboptimal quantum cloning machine. Additionally, the fidelity of our suboptimal quantum cloning machine is higher than or at least equal to that of universal quantum cloning machines and phase-covariant quantum cloning machines. It is also underlined that the suboptimal cloning machine outperforms the "belt quantum cloning machine" for some cases.
Xu, Long; Zhang, Jingwen; Zhao, Hua; Sun, Haibin; Xu, Caixia
2017-09-01
Quasi-period cylindrical nanostructures with both diameters and intervals of about 100 nm are manufactured on the surfaces of Nd 3+ -doped lanthanum lead zirconate titanate ceramics by femtosecond laser irradiation under SF 6 atmosphere. A light-emission enhancement of more than 20 times is investigated, accompanied by an extremely long trailing-off time of light emission and lower threshold. A specific polarization state of the light emission is achieved and tuned by changing the incident regions of the pumping source. The increased absorption coefficient of the specimen is discussed based on multiple scattering and weak localization of light. In addition, both the scatterers provided by the laser-machined nanostructure and the recurrent photoinduced trapping and re-excitation process participated in the enhancement of the light emission. This Letter offers new insight to improve the luminescence property of laser materials, as well as to broaden the range of exploring the weak localization of light and random lasers.
Resonant antenna probes for tip-enhanced infrared near-field microscopy.
Huth, Florian; Chuvilin, Andrey; Schnell, Martin; Amenabar, Iban; Krutokhvostov, Roman; Lopatin, Sergei; Hillenbrand, Rainer
2013-03-13
We report the development of infrared-resonant antenna probes for tip-enhanced optical microscopy. We employ focused-ion-beam machining to fabricate high-aspect ratio gold cones, which replace the standard tip of a commercial Si-based atomic force microscopy cantilever. Calculations show large field enhancements at the tip apex due to geometrical antenna resonances in the cones, which can be precisely tuned throughout a broad spectral range from visible to terahertz frequencies by adjusting the cone length. Spectroscopic analysis of these probes by electron energy loss spectroscopy, Fourier transform infrared spectroscopy, and Fourier transform infrared near-field spectroscopy corroborates their functionality as resonant antennas and verifies the broad tunability. By employing the novel probes in a scattering-type near-field microscope and imaging a single tobacco mosaic virus (TMV), we experimentally demonstrate high-performance mid-infrared nanoimaging of molecular absorption. Our probes offer excellent perspectives for optical nanoimaging and nanospectroscopy, pushing the detection and resolution limits in many applications, including nanoscale infrared mapping of organic, molecular, and biological materials, nanocomposites, or nanodevices.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chikkagoudar, Satish; Chatterjee, Samrat; Thomas, Dennis G.
The absence of a robust and unified theory of cyber dynamics presents challenges and opportunities for using machine learning based data-driven approaches to further the understanding of the behavior of such complex systems. Analysts can also use machine learning approaches to gain operational insights. In order to be operationally beneficial, cybersecurity machine learning based models need to have the ability to: (1) represent a real-world system, (2) infer system properties, and (3) learn and adapt based on expert knowledge and observations. Probabilistic models and Probabilistic graphical models provide these necessary properties and are further explored in this chapter. Bayesian Networksmore » and Hidden Markov Models are introduced as an example of a widely used data driven classification/modeling strategy.« less
Dropout Prediction in E-Learning Courses through the Combination of Machine Learning Techniques
ERIC Educational Resources Information Center
Lykourentzou, Ioanna; Giannoukos, Ioannis; Nikolopoulos, Vassilis; Mpardis, George; Loumos, Vassili
2009-01-01
In this paper, a dropout prediction method for e-learning courses, based on three popular machine learning techniques and detailed student data, is proposed. The machine learning techniques used are feed-forward neural networks, support vector machines and probabilistic ensemble simplified fuzzy ARTMAP. Since a single technique may fail to…
Experimental research of kinetic and dynamic characteristics of temperature movements of machines
NASA Astrophysics Data System (ADS)
Parfenov, I. V.; Polyakov, A. N.
2018-03-01
Nowadays, the urgency of informational support of machines at different stages of their life cycle is increasing in the form of various experimental characteristics that determine the criteria for working capacity. The effectiveness of forming the base of experimental characteristics of machines is related directly to the duration of their field tests. In this research, the authors consider a new technique that allows reducing the duration of full-scale testing of machines by 30%. To this end, three new indicator coefficients were calculated in real time to determine the moments corresponding to the characteristic points. In the work, new terms for thermal characteristics of machine tools are introduced: kinetic and dynamic characteristics of the temperature movements of the machine. This allow taking into account not only the experimental values for the temperature displacements of the elements of the carrier system of the machine, but also their derivatives up to the third order, inclusively. The work is based on experimental data obtained in the course of full-scale thermal tests of a drilling-milling and boring CNC machine.
Machine Learning and Radiology
Wang, Shijun; Summers, Ronald M.
2012-01-01
In this paper, we give a short introduction to machine learning and survey its applications in radiology. We focused on six categories of applications in radiology: medical image segmentation, registration, computer aided detection and diagnosis, brain function or activity analysis and neurological disease diagnosis from fMR images, content-based image retrieval systems for CT or MRI images, and text analysis of radiology reports using natural language processing (NLP) and natural language understanding (NLU). This survey shows that machine learning plays a key role in many radiology applications. Machine learning identifies complex patterns automatically and helps radiologists make intelligent decisions on radiology data such as conventional radiographs, CT, MRI, and PET images and radiology reports. In many applications, the performance of machine learning-based automatic detection and diagnosis systems has shown to be comparable to that of a well-trained and experienced radiologist. Technology development in machine learning and radiology will benefit from each other in the long run. Key contributions and common characteristics of machine learning techniques in radiology are discussed. We also discuss the problem of translating machine learning applications to the radiology clinical setting, including advantages and potential barriers. PMID:22465077
Dictionary Based Machine Translation from Kannada to Telugu
NASA Astrophysics Data System (ADS)
Sindhu, D. V.; Sagar, B. M.
2017-08-01
Machine Translation is a task of translating from one language to another language. For the languages with less linguistic resources like Kannada and Telugu Dictionary based approach is the best approach. This paper mainly focuses on Dictionary based machine translation for Kannada to Telugu. The proposed methodology uses dictionary for translating word by word without much correlation of semantics between them. The dictionary based machine translation process has the following sub process: Morph analyzer, dictionary, transliteration, transfer grammar and the morph generator. As a part of this work bilingual dictionary with 8000 entries is developed and the suffix mapping table at the tag level is built. This system is tested for the children stories. In near future this system can be further improved by defining transfer grammar rules.
Cluster optical coding: from biochips to counterfeit security
NASA Astrophysics Data System (ADS)
Haglmueller, Jakob; Alguel, Yilmaz; Mayer, Christian; Matyushin, Viacheslav; Bauer, Georg; Pittner, Fritz; Leitner, Alfred; Aussenegg, Franz R.; Schalkhammer, Thomas G.
2004-07-01
Spatially tuned resonant nano-clusters allow high local field enhancement when exited by electromagnetic radiation. A number of phenomena had been described and subsequently applied to novel nano- and bionano-devices. Decisive for these types of devices and sensors is the precise nanometric assembly, coupling the local field surrounding a cluster to allow resonance with other elements interacting with this field. In particular, the distance cluster-mirror or cluster-fluorophore gives rise to a variety of enhancement phenomena. High throughput transducers using metal cluster resonance technology are based on surface-enhancement of metal cluster light absorption (SEA). The optical property for the analytical application of metal cluster films is the so-called anomalous absorption. At a well defined nanometric distance of a cluster to a mirror the reflected electromagnetic field has the same phase at the position of the absorbing cluster as the incident fields. This feedback mechanism strongly enhances the effective cluster absorption coefficient. The system is characterised by a narrow reflection minimum. Based on this SEA-phenomenon (licensed to and further developed and optimized by NovemberAG, Germany Erlangen) a number of commercial products have been constructed. Brandsealing(R) uses the patented SEA cluster technology to produce optical codings. Cluster SEA thin film systems show a characteristic color-flip effect and are extremely mechanically and thermally robust. This is the basis for its application as an unique security feature. The specific spectroscopic properties as e.g. narrow band multi-resonance of the cluster layers allow the authentication of the optical code which can be easily achieved with a mobile hand-held reader developed by november AG and Siemens AG. Thus, these features are machine-readable which makes them superior to comparable technologies. Cluster labels are available in two formats: as a label for tamper-proof product packaging, and as a direct label, where label and logo are permanently applied directly and unremovable to the product surface. Together with Infineon Technologies and HUECK FOLIEN, the SEA technology is currently developed as a direct label for e.g. SmartCards.
Machine learning modelling for predicting soil liquefaction susceptibility
NASA Astrophysics Data System (ADS)
Samui, P.; Sitharam, T. G.
2011-01-01
This study describes two machine learning techniques applied to predict liquefaction susceptibility of soil based on the standard penetration test (SPT) data from the 1999 Chi-Chi, Taiwan earthquake. The first machine learning technique which uses Artificial Neural Network (ANN) based on multi-layer perceptions (MLP) that are trained with Levenberg-Marquardt backpropagation algorithm. The second machine learning technique uses the Support Vector machine (SVM) that is firmly based on the theory of statistical learning theory, uses classification technique. ANN and SVM have been developed to predict liquefaction susceptibility using corrected SPT [(N1)60] and cyclic stress ratio (CSR). Further, an attempt has been made to simplify the models, requiring only the two parameters [(N1)60 and peck ground acceleration (amax/g)], for the prediction of liquefaction susceptibility. The developed ANN and SVM models have also been applied to different case histories available globally. The paper also highlights the capability of the SVM over the ANN models.
High performance cutting of aircraft and turbine components
NASA Astrophysics Data System (ADS)
Krämer, A.; Lung, D.; Klocke, F.
2012-04-01
Titanium and nickel-based alloys belong to the group of difficult-to-cut materials. The machining of these high-temperature alloys is characterized by low productivity and low process stability as a result of their physical and mechanical properties. Major problems during the machining of these materials are low applicable cutting speeds due to excessive tool wear, long machining times, and thus high manufacturing costs, as well as the formation of ribbon and snarled chips. Under these conditions automation of the production process is limited. This paper deals with strategies to improve machinability of titanium and nickel-based alloys. Using the example of the nickel-based alloy Inconel 718 high performance cutting with advanced cutting materials, such as PCBN and cutting ceramics, is presented. Afterwards the influence of different cooling strategies, like high-pressure lubricoolant supply and cryogenic cooling, during machining of TiAl6V4 is shown.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ken L. Stratton
The objective of this project is to investigate the applicability of a combined Global Positioning System and Inertial Measurement Unit (GPS/IMU) for information based displays on earthmoving machines and for automated earthmoving machines in the future. This technology has the potential of allowing an information-based product like Caterpillar's Computer Aided Earthmoving System (CAES) to operate in areas with satellite shading. Satellite shading is an issue in open pit mining because machines are routinely required to operate close to high walls, which reduces significantly the amount of the visible sky to the GPS antenna mounted on the machine. An inertial measurementmore » unit is a product, which provides data for the calculation of position based on sensing accelerations and rotation rates of the machine's rigid body. When this information is coupled with GPS it results in a positioning system that can maintain positioning capability during time periods of shading.« less
Quantum Neural Network Based Machine Translator for Hindi to English
Singh, V. P.; Chakraverty, S.
2014-01-01
This paper presents the machine learning based machine translation system for Hindi to English, which learns the semantically correct corpus. The quantum neural based pattern recognizer is used to recognize and learn the pattern of corpus, using the information of part of speech of individual word in the corpus, like a human. The system performs the machine translation using its knowledge gained during the learning by inputting the pair of sentences of Devnagri-Hindi and English. To analyze the effectiveness of the proposed approach, 2600 sentences have been evaluated during simulation and evaluation. The accuracy achieved on BLEU score is 0.7502, on NIST score is 6.5773, on ROUGE-L score is 0.9233, and on METEOR score is 0.5456, which is significantly higher in comparison with Google Translation and Bing Translation for Hindi to English Machine Translation. PMID:24977198
NASA Astrophysics Data System (ADS)
Peng, Chong; Wang, Lun; Liao, T. Warren
2015-10-01
Currently, chatter has become the critical factor in hindering machining quality and productivity in machining processes. To avoid cutting chatter, a new method based on dynamic cutting force simulation model and support vector machine (SVM) is presented for the prediction of chatter stability lobes. The cutting force is selected as the monitoring signal, and the wavelet energy entropy theory is used to extract the feature vectors. A support vector machine is constructed using the MATLAB LIBSVM toolbox for pattern classification based on the feature vectors derived from the experimental cutting data. Then combining with the dynamic cutting force simulation model, the stability lobes diagram (SLD) can be estimated. Finally, the predicted results are compared with existing methods such as zero-order analytical (ZOA) and semi-discretization (SD) method as well as actual cutting experimental results to confirm the validity of this new method.
NASA Astrophysics Data System (ADS)
Zan, Tao; Wang, Min; Hu, Jianzhong
2010-12-01
Machining status monitoring technique by multi-sensors can acquire and analyze the machining process information to implement abnormity diagnosis and fault warning. Statistical quality control technique is normally used to distinguish abnormal fluctuations from normal fluctuations through statistical method. In this paper by comparing the advantages and disadvantages of the two methods, the necessity and feasibility of integration and fusion is introduced. Then an approach that integrates multi-sensors status monitoring and statistical process control based on artificial intelligent technique, internet technique and database technique is brought forward. Based on virtual instrument technique the author developed the machining quality assurance system - MoniSysOnline, which has been used to monitoring the grinding machining process. By analyzing the quality data and AE signal information of wheel dressing process the reason of machining quality fluctuation has been obtained. The experiment result indicates that the approach is suitable for the status monitoring and analyzing of machining process.
Application of Fuzzy TOPSIS for evaluating machining techniques using sustainability metrics
NASA Astrophysics Data System (ADS)
Digalwar, Abhijeet K.
2018-04-01
Sustainable processes and techniques are getting increased attention over the last few decades due to rising concerns over the environment, improved focus on productivity and stringency in environmental as well as occupational health and safety norms. The present work analyzes the research on sustainable machining techniques and identifies techniques and parameters on which sustainability of a process is evaluated. Based on the analysis these parameters are then adopted as criteria’s to evaluate different sustainable machining techniques such as Cryogenic Machining, Dry Machining, Minimum Quantity Lubrication (MQL) and High Pressure Jet Assisted Machining (HPJAM) using a fuzzy TOPSIS framework. In order to facilitate easy arithmetic, the linguistic variables represented by fuzzy numbers are transformed into crisp numbers based on graded mean representation. Cryogenic machining was found to be the best alternative sustainable technique as per the fuzzy TOPSIS framework adopted. The paper provides a method to deal with multi criteria decision making problems in a complex and linguistic environment.
Pre-use anesthesia machine check; certified anesthesia technician based quality improvement audit.
Al Suhaibani, Mazen; Al Malki, Assaf; Al Dosary, Saad; Al Barmawi, Hanan; Pogoku, Mahdhav
2014-01-01
Quality assurance of providing a work ready machine in multiple theatre operating rooms in a tertiary modern medical center in Riyadh. The aim of the following study is to keep high quality environment for workers and patients in surgical operating rooms. Technicians based audit by using key performance indicators to assure inspection, passing test of machine worthiness for use daily and in between cases and in case of unexpected failure to provide quick replacement by ready to use another anesthetic machine. The anesthetic machines in all operating rooms are daily and continuously inspected and passed as ready by technicians and verified by anesthesiologist consultant or assistant consultant. The daily records of each machines were collected then inspected for data analysis by quality improvement committee department for descriptive analysis and report the degree of staff compliance to daily inspection as "met" items. Replaced machine during use and overall compliance. Distractive statistic using Microsoft Excel 2003 tables and graphs of sums and percentages of item studied in this audit. Audit obtained highest compliance percentage and low rate of replacement of machine which indicate unexpected machine state of use and quick machine switch. The authors are able to conclude that following regular inspection and running self-check recommended by the manufacturers can contribute to abort any possibility of hazard of anesthesia machine failure during operation. Furthermore in case of unexpected reason to replace the anesthesia machine in quick maneuver contributes to high assured operative utilization of man machine inter-phase in modern surgical operating rooms.
Grouin, Cyril; Zweigenbaum, Pierre
2013-01-01
In this paper, we present a comparison of two approaches to automatically de-identify medical records written in French: a rule-based system and a machine-learning based system using a conditional random fields (CRF) formalism. Both systems have been designed to process nine identifiers in a corpus of medical records in cardiology. We performed two evaluations: first, on 62 documents in cardiology, and on 10 documents in foetopathology - produced by optical character recognition (OCR) - to evaluate the robustness of our systems. We achieved a 0.843 (rule-based) and 0.883 (machine-learning) exact match overall F-measure in cardiology. While the rule-based system allowed us to achieve good results on nominative (first and last names) and numerical data (dates, phone numbers, and zip codes), the machine-learning approach performed best on more complex categories (postal addresses, hospital names, medical devices, and towns). On the foetopathology corpus, although our systems have not been designed for this corpus and despite OCR character recognition errors, we obtained promising results: a 0.681 (rule-based) and 0.638 (machine-learning) exact-match overall F-measure. This demonstrates that existing tools can be applied to process new documents of lower quality.
View of west elevation of building 18 section of machine ...
View of west elevation of building 18 section of machine shops. Jet Lowe, Haer staff photographer, summer 1995. - Naval Base Philadelphia-Philadelphia Naval Shipyard, Machine Shops, League Island, Philadelphia, Philadelphia County, PA
Industrial femtosecond lasers for machining of heat-sensitive polymers (Conference Presentation)
NASA Astrophysics Data System (ADS)
Hendricks, Frank; Bernard, Benjamin; Matylitsky, Victor V.
2017-03-01
Heat-sensitive materials, such as polymers, are used increasingly in various industrial sectors such as medical device manufacturing and organic electronics. Medical applications include implantable devices like stents, catheters and wires, which need to be structured and cut with minimum heat damage. Also the flat panel display market moves from LCD displays to organic LED (OLED) solutions, which utilize heat-sensitive polymer substrates. In both areas, the substrates often consist of multilayer stacks with different types of materials, such as metals, dielectric layers and polymers with different physical characteristic. The different thermal behavior and laser absorption properties of the materials used makes these stacks difficult to machine using conventional laser sources. Femtosecond lasers are an enabling technology for micromachining of these materials since it is possible to machine ultrafine structures with minimum thermal impact and very precise control over material removed. An industrial femtosecond Spirit HE laser system from Spectra-Physics with pulse duration <400 fs, pulse energies of >120 μJ and average output powers of >16 W is an ideal tool for industrial micromachining of a wide range of materials with highest quality and efficiency. The laser offers process flexibility with programmable pulse energy, repetition rate, and pulse width. In this paper, we provide an overview of machining heat-sensitive materials using Spirit HE laser. In particular, we show how the laser parameters (e.g. laser wavelength, pulse duration, applied energy and repetition rate) and the processing strategy (gas assisted single pass cut vs. multi-scan process) influence the efficiency and quality of laser processing.
An imperialist competitive algorithm for virtual machine placement in cloud computing
NASA Astrophysics Data System (ADS)
Jamali, Shahram; Malektaji, Sepideh; Analoui, Morteza
2017-05-01
Cloud computing, the recently emerged revolution in IT industry, is empowered by virtualisation technology. In this paradigm, the user's applications run over some virtual machines (VMs). The process of selecting proper physical machines to host these virtual machines is called virtual machine placement. It plays an important role on resource utilisation and power efficiency of cloud computing environment. In this paper, we propose an imperialist competitive-based algorithm for the virtual machine placement problem called ICA-VMPLC. The base optimisation algorithm is chosen to be ICA because of its ease in neighbourhood movement, good convergence rate and suitable terminology. The proposed algorithm investigates search space in a unique manner to efficiently obtain optimal placement solution that simultaneously minimises power consumption and total resource wastage. Its final solution performance is compared with several existing methods such as grouping genetic and ant colony-based algorithms as well as bin packing heuristic. The simulation results show that the proposed method is superior to other tested algorithms in terms of power consumption, resource wastage, CPU usage efficiency and memory usage efficiency.
Study on The Effectiveness of Egg Tray and Coir Fibre as A Sound Absorber
NASA Astrophysics Data System (ADS)
Kaamin, Masiri; Farah Atiqah Ahmad, Nor; Ngadiman, Norhayati; Kadir, Aslila Abdul; Razali, Siti Nooraiin Mohd; Mokhtar, Mardiha; Sahat, Suhaila
2018-03-01
Sound or noise pollution has become one major issues to the community especially those who lived in the urban areas. It does affect the activity of human life. This excessive noise is mainly caused by machines, traffic, motor vehicles and also any unwanted sounds that coming from outside and even from the inside of the building. Such as a loud music. Therefore, the installation of sound absorption panel is one way to reduce the noise pollution inside a building. The selected material must be a porous and hollow in order to absorb high frequency sound. This study was conducted to evaluate the potential of egg tray and coir fibre as a sound absorption panel. The coir fibre has a good coefficient value which make it suitable as a sound absorption material and can replace the traditional material; syntactic and wooden material. The combination of pyramid shape of egg tray can provide a large surface for uniform sound reflection. This study was conducted by using a panel with size 1 m x 1 m with a thickness of 6 mm. This panel consist of egg tray layer, coir fibre layer and a fabric as a wrapping for the aesthetic value. Room reverberation test has been carried to find the loss of reverberation time (RT). Result shows that, a reverberation time reading is on low frequency, which is 125 Hz to 1600 Hz. Within these frequencies, this panel can shorten the reverberation time of 5.63s to 3.60s. Hence, from this study, it can be concluded that the selected materials have the potential as a good sound absorption panel. The comparison is made with the previous research that used egg tray and kapok as a sound absorption panel.
NASA Astrophysics Data System (ADS)
Robinson, Iain; Jack, James W.; Rae, Cameron F.; Moncrieff, John B.
2015-10-01
We report the development of a differential absorption lidar instrument (DIAL) designed and built specifically for the measurement of anthropogenic greenhouse gases in the atmosphere. The DIAL is integrated into a commercial astronomical telescope to provide high-quality receiver optics and enable automated scanning for three-dimensional lidar acquisition. The instrument is portable and can be set up within a few hours in the field. The laser source is a pulsed optical parametric oscillator (OPO) which outputs light at a wavelength tunable near 1.6 μm. This wavelength region, which is also used in telecommunications devices, provides access to absorption lines in both carbon dioxide at 1573 nm and methane at 1646 nm. To achieve the critical temperature stability required for a laserbased field instrument the four-mirror OPO cavity is machined from a single aluminium block. A piezoactuator adjusts the cavity length to achieve resonance and this is maintained over temperature changes through the use of a feedback loop. The laser output is continuously monitored with pyroelectric detectors and a custom-built wavemeter. The OPO is injection seeded by a temperature-stabilized distributed feedback laser diode (DFB-LD) with a wavelength locked to the absorption line centre (on-line) using a gas cell containing pure carbon dioxide. A second DFB-LD is tuned to a nearby wavelength (off-line) to provide the reference required for differential absorption measurements. A similar system has been designed and built to provide the injection seeding wavelengths for methane. The system integrates the DFB-LDs, drivers, locking electronics, gas cell and balanced photodetectors. The results of test measurements of carbon dioxide are presented and the development of the system is discussed, including the adaptation required for the measurement of methane.
Discovering Fine-grained Sentiment in Suicide Notes
Wang, Wenbo; Chen, Lu; Tan, Ming; Wang, Shaojun; Sheth, Amit P.
2012-01-01
This paper presents our solution for the i2b2 sentiment classification challenge. Our hybrid system consists of machine learning and rule-based classifiers. For the machine learning classifier, we investigate a variety of lexical, syntactic and knowledge-based features, and show how much these features contribute to the performance of the classifier through experiments. For the rule-based classifier, we propose an algorithm to automatically extract effective syntactic and lexical patterns from training examples. The experimental results show that the rule-based classifier outperforms the baseline machine learning classifier using unigram features. By combining the machine learning classifier and the rule-based classifier, the hybrid system gains a better trade-off between precision and recall, and yields the highest micro-averaged F-measure (0.5038), which is better than the mean (0.4875) and median (0.5027) micro-average F-measures among all participating teams. PMID:22879770
NASA's online machine aided indexing system
NASA Technical Reports Server (NTRS)
Silvester, June P.; Genuardi, Michael T.; Klingbiel, Paul H.
1993-01-01
This report describes the NASA Lexical Dictionary, a machine aided indexing system used online at the National Aeronautics and Space Administration's Center for Aerospace Information (CASI). This system is comprised of a text processor that is based on the computational, non-syntactic analysis of input text, and an extensive 'knowledge base' that serves to recognize and translate text-extracted concepts. The structure and function of the various NLD system components are described in detail. Methods used for the development of the knowledge base are discussed. Particular attention is given to a statistically-based text analysis program that provides the knowledge base developer with a list of concept-specific phrases extracted from large textual corpora. Production and quality benefits resulting from the integration of machine aided indexing at CASI are discussed along with a number of secondary applications of NLD-derived systems including on-line spell checking and machine aided lexicography.
Moreno-Tapia, Sandra Veronica; Vera-Salas, Luis Alberto; Osornio-Rios, Roque Alfredo; Dominguez-Gonzalez, Aurelio; Stiharu, Ion; de Jesus Romero-Troncoso, Rene
2010-01-01
Computer numerically controlled (CNC) machines have evolved to adapt to increasing technological and industrial requirements. To cover these needs, new generation machines have to perform monitoring strategies by incorporating multiple sensors. Since in most of applications the online Processing of the variables is essential, the use of smart sensors is necessary. The contribution of this work is the development of a wireless network platform of reconfigurable smart sensors for CNC machine applications complying with the measurement requirements of new generation CNC machines. Four different smart sensors are put under test in the network and their corresponding signal processing techniques are implemented in a Field Programmable Gate Array (FPGA)-based sensor node. PMID:22163602
Moreno-Tapia, Sandra Veronica; Vera-Salas, Luis Alberto; Osornio-Rios, Roque Alfredo; Dominguez-Gonzalez, Aurelio; Stiharu, Ion; Romero-Troncoso, Rene de Jesus
2010-01-01
Computer numerically controlled (CNC) machines have evolved to adapt to increasing technological and industrial requirements. To cover these needs, new generation machines have to perform monitoring strategies by incorporating multiple sensors. Since in most of applications the online Processing of the variables is essential, the use of smart sensors is necessary. The contribution of this work is the development of a wireless network platform of reconfigurable smart sensors for CNC machine applications complying with the measurement requirements of new generation CNC machines. Four different smart sensors are put under test in the network and their corresponding signal processing techniques are implemented in a Field Programmable Gate Array (FPGA)-based sensor node.
Predictive Modeling and Optimization of Vibration-assisted AFM Tip-based Nanomachining
NASA Astrophysics Data System (ADS)
Kong, Xiangcheng
The tip-based vibration-assisted nanomachining process offers a low-cost, low-effort technique in fabricating nanometer scale 2D/3D structures in sub-100 nm regime. To understand its mechanism, as well as provide the guidelines for process planning and optimization, we have systematically studied this nanomachining technique in this work. To understand the mechanism of this nanomachining technique, we firstly analyzed the interaction between the AFM tip and the workpiece surface during the machining process. A 3D voxel-based numerical algorithm has been developed to calculate the material removal rate as well as the contact area between the AFM tip and the workpiece surface. As a critical factor to understand the mechanism of this nanomachining process, the cutting force has been analyzed and modeled. A semi-empirical model has been proposed by correlating the cutting force with the material removal rate, which was validated using experimental data from different machining conditions. With the understanding of its mechanism, we have developed guidelines for process planning of this nanomachining technique. To provide the guideline for parameter selection, the effect of machining parameters on the feature dimensions (depth and width) has been analyzed. Based on ANOVA test results, the feature width is only controlled by the XY vibration amplitude, while the feature depth is affected by several machining parameters such as setpoint force and feed rate. A semi-empirical model was first proposed to predict the machined feature depth under given machining condition. Then, to reduce the computation intensity, linear and nonlinear regression models were also proposed and validated using experimental data. Given the desired feature dimensions, feasible machining parameters could be provided using these predictive feature dimension models. As the tip wear is unavoidable during the machining process, the machining precision will gradually decrease. To maintain the machining quality, the guideline for when to change the tip should be provided. In this study, we have developed several metrics to detect tip wear, such as tip radius and the pull-off force. The effect of machining parameters on the tip wear rate has been studied using these metrics, and the machining distance before a tip must be changed has been modeled using these machining parameters. Finally, the optimization functions have been built for unit production time and unit production cost subject to realistic constraints, and the optimal machining parameters can be found by solving these functions.
Machine-Learning Approach for Design of Nanomagnetic-Based Antennas
NASA Astrophysics Data System (ADS)
Gianfagna, Carmine; Yu, Huan; Swaminathan, Madhavan; Pulugurtha, Raj; Tummala, Rao; Antonini, Giulio
2017-08-01
We propose a machine-learning approach for design of planar inverted-F antennas with a magneto-dielectric nanocomposite substrate. It is shown that machine-learning techniques can be efficiently used to characterize nanomagnetic-based antennas by accurately mapping the particle radius and volume fraction of the nanomagnetic material to antenna parameters such as gain, bandwidth, radiation efficiency, and resonant frequency. A modified mixing rule model is also presented. In addition, the inverse problem is addressed through machine learning as well, where given the antenna parameters, the corresponding design space of possible material parameters is identified.
On the decomposition of synchronous state mechines using sequence invariant state machines
NASA Technical Reports Server (NTRS)
Hebbalalu, K.; Whitaker, S.; Cameron, K.
1992-01-01
This paper presents a few techniques for the decomposition of Synchronous State Machines of medium to large sizes into smaller component machines. The methods are based on the nature of the transitions and sequences of states in the machine and on the number and variety of inputs to the machine. The results of the decomposition, and of using the Sequence Invariant State Machine (SISM) Design Technique for generating the component machines, include great ease and quickness in the design and implementation processes. Furthermore, there is increased flexibility in making modifications to the original design leading to negligible re-design time.
NASA Astrophysics Data System (ADS)
Yu, Jianbo
2017-01-01
This study proposes an adaptive-learning-based method for machine faulty detection and health degradation monitoring. The kernel of the proposed method is an "evolving" model that uses an unsupervised online learning scheme, in which an adaptive hidden Markov model (AHMM) is used for online learning the dynamic health changes of machines in their full life. A statistical index is developed for recognizing the new health states in the machines. Those new health states are then described online by adding of new hidden states in AHMM. Furthermore, the health degradations in machines are quantified online by an AHMM-based health index (HI) that measures the similarity between two density distributions that describe the historic and current health states, respectively. When necessary, the proposed method characterizes the distinct operating modes of the machine and can learn online both abrupt as well as gradual health changes. Our method overcomes some drawbacks of the HIs (e.g., relatively low comprehensibility and applicability) based on fixed monitoring models constructed in the offline phase. Results from its application in a bearing life test reveal that the proposed method is effective in online detection and adaptive assessment of machine health degradation. This study provides a useful guide for developing a condition-based maintenance (CBM) system that uses an online learning method without considerable human intervention.
NASA Astrophysics Data System (ADS)
Wang, Yang; Zhou, Lin; Zheng, Qinghui; Lu, Hong; Gan, Qiaoqiang; Yu, Zongfu; Zhu, Jia
2017-05-01
Spectrally selective absorbers (SSA) with high selectivity of absorption and sharp cut-off between high absorptivity and low emissivity are critical for efficient solar energy conversion. Here, we report the semiconductor nanowire enabled SSA with not only high absorption selectivity but also temperature dependent sharp absorption cut-off. By taking advantage of the temperature dependent bandgap of semiconductors, we systematically demonstrate that the absorption cut-off profile of the semiconductor-nanowire-based SSA can be flexibly tuned, which is quite different from most of the other SSA reported so far. As an example, silicon nanowire based selective absorbers are fabricated, with the measured absorption efficiency above (below) bandgap ˜97% (15%) combined with an extremely sharp absorption cut-off (transition region ˜200 nm), the sharpest SSA demonstrated so far. The demonstrated semiconductor-nanowire-based SSA can enable a high solar thermal efficiency of ≳86% under a wide range of operating conditions, which would be competitive candidates for the concentrated solar energy utilizations.
NASA Astrophysics Data System (ADS)
Datta, Jinia; Chowdhuri, Sumana; Bera, Jitendranath
2016-12-01
This paper presents a novel scheme of remote condition monitoring of multi machine system where a secured and coded data of induction machine with different parameters is communicated between a state-of-the-art dedicated hardware Units (DHU) installed at the machine terminal and a centralized PC based machine data management (MDM) software. The DHUs are built for acquisition of different parameters from the respective machines, and hence are placed at their nearby panels in order to acquire different parameters cost effectively during their running condition. The MDM software collects these data through a communication channel where all the DHUs are networked using RS485 protocol. Before transmitting, the parameter's related data is modified with the adoption of differential pulse coded modulation (DPCM) and Huffman coding technique. It is further encrypted with a private key where different keys are used for different DHUs. In this way a data security scheme is adopted during its passage through the communication channel in order to avoid any third party attack into the channel. The hybrid mode of DPCM and Huffman coding is chosen to reduce the data packet length. A MATLAB based simulation and its practical implementation using DHUs at three machine terminals (one healthy three phase, one healthy single phase and one faulty three phase machine) proves its efficacy and usefulness for condition based maintenance of multi machine system. The data at the central control room are decrypted and decoded using MDM software. In this work it is observed that Chanel efficiency with respect to different parameter measurements has been increased very much.
NASA Technical Reports Server (NTRS)
Merrick, R. H.; Anderson, P. P.
1973-01-01
The possible use of solar energy powered absorption units to provide cooling and heating of residential buildings is studied. Both, the ammonia-water and the water-lithium bromide cycles, are considered. It is shown that the air cooled ammonia water unit does not meet the criteria for COP and pump power on the cooling cycle and the heat obtained from it acting as a heat pump is at too low a temperature. If the ammonia machine is water cooled it will meet the design criteria for cooling but can not supply the heating needs. The water cooled lithium bromide unit meets the specified performance for cooling with appreciably lower generator temperatures and without a mechanical solution pump. It is recommeded that in the demonstration project a direct expansion lithium bromide unit be used for cooling and an auxiliary duct coil using the solar heated water be employed for heating.
All-Optical Cantilever-Enhanced Photoacoustic Spectroscopy in the Open Environment
NASA Astrophysics Data System (ADS)
Wei, Wei; Zhu, Yong; Lin, Cheng; Tian, Li; Xu, Zhuwen; Nong, Jinpeng
2015-06-01
A novel all-optical cantilever-enhanced photoacoustic spectroscopy technique for trace gas detection in the open environment is proposed. A cantilever is set off-beam to "listen to" the photoacoustic signal, and an improved quadrature-point stabilization Fabry-Perot demodulation unit is used to pick up the vibration signal of the acoustic transducer instead of a complicated Michelson interferometer. The structure parameters of the cantilever are optimized to make the sensing system work more stably and reliably using a finite element method, which is then fabricated by surface micro-machining technology. Finally, related experiments are carried out to detect the absorption of water vapor at one atmosphere in the open environment. It was found that the normalized noise-equivalent absorption coefficient obtained by a traditional Fabry-Perot demodulation unit is , while that by a quadrature- point stabilization Fabry-Perot demodulation unit is , which indicates that the sensitivity is increased by a factor of 3.1 using improved cantilever-enhanced photoacoustic spectroscopy.
Machinability of nickel based alloys using electrical discharge machining process
NASA Astrophysics Data System (ADS)
Khan, M. Adam; Gokul, A. K.; Bharani Dharan, M. P.; Jeevakarthikeyan, R. V. S.; Uthayakumar, M.; Thirumalai Kumaran, S.; Duraiselvam, M.
2018-04-01
The high temperature materials such as nickel based alloys and austenitic steel are frequently used for manufacturing critical aero engine turbine components. Literature on conventional and unconventional machining of steel materials is abundant over the past three decades. However the machining studies on superalloy is still a challenging task due to its inherent property and quality. Thus this material is difficult to be cut in conventional processes. Study on unconventional machining process for nickel alloys is focused in this proposed research. Inconel718 and Monel 400 are the two different candidate materials used for electrical discharge machining (EDM) process. Investigation is to prepare a blind hole using copper electrode of 6mm diameter. Electrical parameters are varied to produce plasma spark for diffusion process and machining time is made constant to calculate the experimental results of both the material. Influence of process parameters on tool wear mechanism and material removal are considered from the proposed experimental design. While machining the tool has prone to discharge more materials due to production of high energy plasma spark and eddy current effect. The surface morphology of the machined surface were observed with high resolution FE SEM. Fused electrode found to be a spherical structure over the machined surface as clumps. Surface roughness were also measured with surface profile using profilometer. It is confirmed that there is no deviation and precise roundness of drilling is maintained.
NASA Astrophysics Data System (ADS)
Sharif, Safian; Sadiq, Ibrahim Ogu; Suhaimi, Mohd Azlan; Rahim, Shayfull Zamree Abd
2017-09-01
Pollution related activities in addition to handling cost of conventional cutting fluid application in metal cutting industry has generated a lot of concern over time. The desire for a green machining environment which will preserve the environment through reduction or elimination of machining related pollution, reduction in oil consumption and safety of the machine operators without compromising an efficient machining process led to search for alternatives to conventional cutting fluid. Amongst the alternatives of dry machining, cryogenic cooling, high pressure cooling, near dry or minimum quantity lubrication (MQL), MQL have shown remarkable performance in terms of cost, machining output, safety of environment and machine operators. However, the MQL under aggressive machining or very high speed machining pose certain restriction as the lubrication media cannot perform efficiently at elevated temperature. In compensating for the shortcomings of MQL technique, high thermal conductivity nanoparticles are introduced in cutting fluids for use in the MQL lubrication process. They have indicated enhanced performance of machining process and significant reduction of loads on the environment. The present work is aimed at evaluating the application and performance of nanofluid in metal cutting process through MQL lubrication technique highlighting their impacts and prospects as lubrication strategy in metal cutting process for sustainable green manufacturing. Enhanced performance of vegetable oil based nanofluids over mineral oil-based nanofluids have been reported and thus highlighted.
Diamond Turning Of Infra-Red Components
NASA Astrophysics Data System (ADS)
Hodgson, B.; Lettington, A. H.; Stillwell, P. F. T. C.
1986-05-01
Single point diamond machining of infra-red optical components such as aluminium mirrors, germanium lenses and zinc sulphide domes is potentially the most cost effective method for their manufacture since components may be machined from the blanks to a high surface finish, requiring no subsequent polishing, in a few minutes. Machines for the production of flat surfaces are well established. Diamond turning lathes for curved surfaces however require a high capital investment which can be justified only for research purposes or high volume production. The present paper describes the development of a low cost production machine based on a Bryant Symons diamond turning lathe which is able to machine spherical components to the required form and finish. It employs two horizontal spindles one for the workpiece the other for the tool. The machined radius of curvature is set by the alignment of the axes and the radius of the tool motion, as in conventional generation. The diamond tool is always normal to the workpiece and does not need to be accurately profiled. There are two variants of this basic machine. For machining hemispherical domes the axes are at right angles while for lenses with positive or negative curvature these axes are adjustable. An aspherical machine is under development, based on the all mechanical spherical machine, but in which a ± 2 mm aspherecity may be imposed on the best fit sphere by moving the work spindle under numerical control.
Zhang, Xiaodong; Zeng, Zhen; Liu, Xianlei; Fang, Fengzhou
2015-09-21
Freeform surface is promising to be the next generation optics, however it needs high form accuracy for excellent performance. The closed-loop of fabrication-measurement-compensation is necessary for the improvement of the form accuracy. It is difficult to do an off-machine measurement during the freeform machining because the remounting inaccuracy can result in significant form deviations. On the other side, on-machine measurement may hides the systematic errors of the machine because the measuring device is placed in situ on the machine. This study proposes a new compensation strategy based on the combination of on-machine and off-machine measurement. The freeform surface is measured in off-machine mode with nanometric accuracy, and the on-machine probe achieves accurate relative position between the workpiece and machine after remounting. The compensation cutting path is generated according to the calculated relative position and shape errors to avoid employing extra manual adjustment or highly accurate reference-feature fixture. Experimental results verified the effectiveness of the proposed method.
A Hybrid Method for Opinion Finding Task (KUNLP at TREC 2008 Blog Track)
2008-11-01
retrieve relevant documents. For the Opinion Retrieval subtask, we propose a hybrid model of lexicon-based approach and machine learning approach for...estimating and ranking the opinionated documents. For the Polarized Opinion Retrieval subtask, we employ machine learning for predicting the polarity...and linear combination technique for ranking polar documents. The hybrid model which utilize both lexicon-based approach and machine learning approach
Modelling of internal architecture of kinesin nanomotor as a machine language.
Khataee, H R; Ibrahim, M Y
2012-09-01
Kinesin is a protein-based natural nanomotor that transports molecular cargoes within cells by walking along microtubules. Kinesin nanomotor is considered as a bio-nanoagent which is able to sense the cell through its sensors (i.e. its heads and tail), make the decision internally and perform actions on the cell through its actuator (i.e. its motor domain). The study maps the agent-based architectural model of internal decision-making process of kinesin nanomotor to a machine language using an automata algorithm. The applied automata algorithm receives the internal agent-based architectural model of kinesin nanomotor as a deterministic finite automaton (DFA) model and generates a regular machine language. The generated regular machine language was acceptable by the architectural DFA model of the nanomotor and also in good agreement with its natural behaviour. The internal agent-based architectural model of kinesin nanomotor indicates the degree of autonomy and intelligence of the nanomotor interactions with its cell. Thus, our developed regular machine language can model the degree of autonomy and intelligence of kinesin nanomotor interactions with its cell as a language. Modelling of internal architectures of autonomous and intelligent bio-nanosystems as machine languages can lay the foundation towards the concept of bio-nanoswarms and next phases of the bio-nanorobotic systems development.
Osteoporosis risk prediction using machine learning and conventional methods.
Kim, Sung Kean; Yoo, Tae Keun; Oh, Ein; Kim, Deok Won
2013-01-01
A number of clinical decision tools for osteoporosis risk assessment have been developed to select postmenopausal women for the measurement of bone mineral density. We developed and validated machine learning models with the aim of more accurately identifying the risk of osteoporosis in postmenopausal women, and compared with the ability of a conventional clinical decision tool, osteoporosis self-assessment tool (OST). We collected medical records from Korean postmenopausal women based on the Korea National Health and Nutrition Surveys (KNHANES V-1). The training data set was used to construct models based on popular machine learning algorithms such as support vector machines (SVM), random forests (RF), artificial neural networks (ANN), and logistic regression (LR) based on various predictors associated with low bone density. The learning models were compared with OST. SVM had significantly better area under the curve (AUC) of the receiver operating characteristic (ROC) than ANN, LR, and OST. Validation on the test set showed that SVM predicted osteoporosis risk with an AUC of 0.827, accuracy of 76.7%, sensitivity of 77.8%, and specificity of 76.0%. We were the first to perform comparisons of the performance of osteoporosis prediction between the machine learning and conventional methods using population-based epidemiological data. The machine learning methods may be effective tools for identifying postmenopausal women at high risk for osteoporosis.
Temperature Measurement and Numerical Prediction in Machining Inconel 718.
Díaz-Álvarez, José; Tapetado, Alberto; Vázquez, Carmen; Miguélez, Henar
2017-06-30
Thermal issues are critical when machining Ni-based superalloy components designed for high temperature applications. The low thermal conductivity and extreme strain hardening of this family of materials results in elevated temperatures around the cutting area. This elevated temperature could lead to machining-induced damage such as phase changes and residual stresses, resulting in reduced service life of the component. Measurement of temperature during machining is crucial in order to control the cutting process, avoiding workpiece damage. On the other hand, the development of predictive tools based on numerical models helps in the definition of machining processes and the obtainment of difficult to measure parameters such as the penetration of the heated layer. However, the validation of numerical models strongly depends on the accurate measurement of physical parameters such as temperature, ensuring the calibration of the model. This paper focuses on the measurement and prediction of temperature during the machining of Ni-based superalloys. The temperature sensor was based on a fiber-optic two-color pyrometer developed for localized temperature measurements in turning of Inconel 718. The sensor is capable of measuring temperature in the range of 250 to 1200 °C. Temperature evolution is recorded in a lathe at different feed rates and cutting speeds. Measurements were used to calibrate a simplified numerical model for prediction of temperature fields during turning.
NASA Astrophysics Data System (ADS)
Song, Jinghui; Yuan, Hui; Xia, Yunfeng; Kan, Weimin; Deng, Xiaowen; Liu, Shi; Liang, Wanlong; Deng, Jianhua
2018-03-01
This paper introduces the working principle and system constitution of the linear Fresnel solar lithium bromide absorption refrigeration cycle, and elaborates several typical structures of absorption refrigeration cycle, including single-effect, two-stage cycle and double-effect lithium bromide absorption refrigeration cycle A 1.n effect absorption chiller system based on the best parameters was introduced and applied to a linear Fresnel solar absorption chiller system. Through the field refrigerator performance test, the results show: Based on this heat cycle design and processing 1.n lithium bromide absorption refrigeration power up to 35.2KW, It can meet the theoretical expectations and has good flexibility and reliability, provides guidance for the use of solar thermal energy.
Bishop, Christopher M
2013-02-13
Several decades of research in the field of machine learning have resulted in a multitude of different algorithms for solving a broad range of problems. To tackle a new application, a researcher typically tries to map their problem onto one of these existing methods, often influenced by their familiarity with specific algorithms and by the availability of corresponding software implementations. In this study, we describe an alternative methodology for applying machine learning, in which a bespoke solution is formulated for each new application. The solution is expressed through a compact modelling language, and the corresponding custom machine learning code is then generated automatically. This model-based approach offers several major advantages, including the opportunity to create highly tailored models for specific scenarios, as well as rapid prototyping and comparison of a range of alternative models. Furthermore, newcomers to the field of machine learning do not have to learn about the huge range of traditional methods, but instead can focus their attention on understanding a single modelling environment. In this study, we show how probabilistic graphical models, coupled with efficient inference algorithms, provide a very flexible foundation for model-based machine learning, and we outline a large-scale commercial application of this framework involving tens of millions of users. We also describe the concept of probabilistic programming as a powerful software environment for model-based machine learning, and we discuss a specific probabilistic programming language called Infer.NET, which has been widely used in practical applications.
A Sensor-Based Method for Diagnostics of Machine Tool Linear Axes.
Vogl, Gregory W; Weiss, Brian A; Donmez, M Alkan
2015-01-01
A linear axis is a vital subsystem of machine tools, which are vital systems within many manufacturing operations. When installed and operating within a manufacturing facility, a machine tool needs to stay in good condition for parts production. All machine tools degrade during operations, yet knowledge of that degradation is illusive; specifically, accurately detecting degradation of linear axes is a manual and time-consuming process. Thus, manufacturers need automated and efficient methods to diagnose the condition of their machine tool linear axes without disruptions to production. The Prognostics and Health Management for Smart Manufacturing Systems (PHM4SMS) project at the National Institute of Standards and Technology (NIST) developed a sensor-based method to quickly estimate the performance degradation of linear axes. The multi-sensor-based method uses data collected from a 'sensor box' to identify changes in linear and angular errors due to axis degradation; the sensor box contains inclinometers, accelerometers, and rate gyroscopes to capture this data. The sensors are expected to be cost effective with respect to savings in production losses and scrapped parts for a machine tool. Numerical simulations, based on sensor bandwidth and noise specifications, show that changes in straightness and angular errors could be known with acceptable test uncertainty ratios. If a sensor box resides on a machine tool and data is collected periodically, then the degradation of the linear axes can be determined and used for diagnostics and prognostics to help optimize maintenance, production schedules, and ultimately part quality.
Bishop, Christopher M.
2013-01-01
Several decades of research in the field of machine learning have resulted in a multitude of different algorithms for solving a broad range of problems. To tackle a new application, a researcher typically tries to map their problem onto one of these existing methods, often influenced by their familiarity with specific algorithms and by the availability of corresponding software implementations. In this study, we describe an alternative methodology for applying machine learning, in which a bespoke solution is formulated for each new application. The solution is expressed through a compact modelling language, and the corresponding custom machine learning code is then generated automatically. This model-based approach offers several major advantages, including the opportunity to create highly tailored models for specific scenarios, as well as rapid prototyping and comparison of a range of alternative models. Furthermore, newcomers to the field of machine learning do not have to learn about the huge range of traditional methods, but instead can focus their attention on understanding a single modelling environment. In this study, we show how probabilistic graphical models, coupled with efficient inference algorithms, provide a very flexible foundation for model-based machine learning, and we outline a large-scale commercial application of this framework involving tens of millions of users. We also describe the concept of probabilistic programming as a powerful software environment for model-based machine learning, and we discuss a specific probabilistic programming language called Infer.NET, which has been widely used in practical applications. PMID:23277612
A Sensor-Based Method for Diagnostics of Machine Tool Linear Axes
Vogl, Gregory W.; Weiss, Brian A.; Donmez, M. Alkan
2017-01-01
A linear axis is a vital subsystem of machine tools, which are vital systems within many manufacturing operations. When installed and operating within a manufacturing facility, a machine tool needs to stay in good condition for parts production. All machine tools degrade during operations, yet knowledge of that degradation is illusive; specifically, accurately detecting degradation of linear axes is a manual and time-consuming process. Thus, manufacturers need automated and efficient methods to diagnose the condition of their machine tool linear axes without disruptions to production. The Prognostics and Health Management for Smart Manufacturing Systems (PHM4SMS) project at the National Institute of Standards and Technology (NIST) developed a sensor-based method to quickly estimate the performance degradation of linear axes. The multi-sensor-based method uses data collected from a ‘sensor box’ to identify changes in linear and angular errors due to axis degradation; the sensor box contains inclinometers, accelerometers, and rate gyroscopes to capture this data. The sensors are expected to be cost effective with respect to savings in production losses and scrapped parts for a machine tool. Numerical simulations, based on sensor bandwidth and noise specifications, show that changes in straightness and angular errors could be known with acceptable test uncertainty ratios. If a sensor box resides on a machine tool and data is collected periodically, then the degradation of the linear axes can be determined and used for diagnostics and prognostics to help optimize maintenance, production schedules, and ultimately part quality. PMID:28691039
Cleaning of uranium vs machine coolant formulations
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cristy, S.S.; Byrd, V.R.; Simandl, R.F.
1984-10-01
This study compares methods for cleaning uranium chips and the residues left on chips from alternate machine coolants based on propylene glycol-water mixtures with either borax, ammonium tetraborate, or triethanolamine tetraborate added as a nuclear poison. Residues left on uranium surfaces machined with perchloroethylene-mineral oil coolant and on surfaces machined with the borax-containing alternate coolant were also compared. In comparing machined surfaces, greater chlorine contamination was found on the surface of the perchloroethylene-mineral oil machined surfaces, but slightly greater oxidation was found on the surfaces machined with the alternate borax-containing coolant. Overall, the differences were small and a change tomore » the alternate coolant does not appear to constitute a significant threat to the integrity of machined uranium parts.« less
Modeling and simulation of five-axis virtual machine based on NX
NASA Astrophysics Data System (ADS)
Li, Xiaoda; Zhan, Xianghui
2018-04-01
Virtual technology in the machinery manufacturing industry has shown the role of growing. In this paper, the Siemens NX software is used to model the virtual CNC machine tool, and the parameters of the virtual machine are defined according to the actual parameters of the machine tool so that the virtual simulation can be carried out without loss of the accuracy of the simulation. How to use the machine builder of the CAM module to define the kinematic chain and machine components of the machine is described. The simulation of virtual machine can provide alarm information of tool collision and over cutting during the process to users, and can evaluate and forecast the rationality of the technological process.
OH detection by Ford Motor Company
NASA Technical Reports Server (NTRS)
Wang, Charles C.
1986-01-01
Two different methods for detection of OH are presented: a low pressure flow cell system and a frequency modulation absorption measurement. Using conventional absorption spectroscopy, detection limits were quoted of 1,000,000 OH molecules per cu cm using a 30-minute averaging time on the ground, and a 3-hour averaging time in the air for present apparatus in use. With the addition of FM spectroscopy at 1 GHz, a double-beam machine should permit detectable absorption of and an OH limit of 100,000 per cu cm in a 30-minute averaging time. In the low pressure system on which experiments are ongoing nonexponential time behavior was observed after the decay had progressed to about 0.3 of its original level; this was attributed to ion emission in the photomultiplier. A flame source with OH present at high concentration levels was used as a calibration. It was estimated that within the sampling chamber, 400,000 OH could be measured. With a factor-of-2 loss at the sampling orifice, this means detectability of 5 to 8 x 100,000 cu cm at the present time. This could be reduced by a factor of 2 in one hour averaging time; improvements in laser bandwidth and energy should provide another factor of 2 in sensitivity.
OH detection by Ford Motor Company
NASA Astrophysics Data System (ADS)
Wang, Charles C.
1986-12-01
Two different methods for detection of OH are presented: a low pressure flow cell system and a frequency modulation absorption measurement. Using conventional absorption spectroscopy, detection limits were quoted of 1,000,000 OH molecules per cu cm using a 30-minute averaging time on the ground, and a 3-hour averaging time in the air for present apparatus in use. With the addition of FM spectroscopy at 1 GHz, a double-beam machine should permit detectable absorption of and an OH limit of 100,000 per cu cm in a 30-minute averaging time. In the low pressure system on which experiments are ongoing nonexponential time behavior was observed after the decay had progressed to about 0.3 of its original level; this was attributed to ion emission in the photomultiplier. A flame source with OH present at high concentration levels was used as a calibration. It was estimated that within the sampling chamber, 400,000 OH could be measured. With a factor-of-2 loss at the sampling orifice, this means detectability of 5 to 8 x 100,000 cu cm at the present time. This could be reduced by a factor of 2 in one hour averaging time; improvements in laser bandwidth and energy should provide another factor of 2 in sensitivity.
Influence of Stacking Sequence and Notch Angle on the Charpy Impact Behavior of Hybrid Composites
NASA Astrophysics Data System (ADS)
Behnia, S.; Daghigh, V.; Nikbin, K.; Fereidoon, A.; Ghorbani, J.
2016-09-01
The low-velocity impact behavior of hybrid composite laminates was investigated. The epoxy matrix was reinforced with aramid, glass, basalt, and carbon fabrics using the hand lay-up technique. Different stacking sequences and notch angles were and notch angles considered and tested using a Charpy impact testing machine to study the hybridization and notch angle effects on the impact response of the hybrid composites. The energy absorption capability of specimens with different stacking sequences and notch angles is compared and discussed. It is shown that the hybridization can enhance the mechanical performance of composite materials.
A cryogenic thermal source for detector array characterization
NASA Astrophysics Data System (ADS)
Chuss, David T.; Rostem, Karwan; Wollack, Edward J.; Berman, Leah; Colazo, Felipe; DeGeorge, Martin; Helson, Kyle; Sagliocca, Marco
2017-10-01
We describe the design, fabrication, and validation of a cryogenically compatible quasioptical thermal source for characterization of detector arrays. The source is constructed using a graphite-loaded epoxy mixture that is molded into a tiled pyramidal structure. The mold is fabricated using a hardened steel template produced via a wire electron discharge machining process. The absorptive mixture is bonded to a copper backplate enabling thermalization of the entire structure and measurement of the source temperature. Measurements indicate that the reflectance of the source is <0.001 across a spectral band extending from 75 to 330 GHz.
Theoretical and Experimental Research on a Millimeter-Wavelength Free-Electron Laser
1989-09-01
Plauma Sci. vol. PS-3, pp. 1-5, 1975. off (Fig. 7); this may be due to the TEo2 cutoff of the 5 cm [5] A. Grossman and T. C. Marshall, "Orbits of a test...from maycor (a machineable glass ), in the form of a N ihin-walled cone. Thermistors attached to the cone de-N 1- v/ " liver a signal which unbalances a...0.7; this is given by using a calorimeter cone fabricated of "Macor." a ma- eBI, nc chineable glass with high absorption at millimeter wave- vl = (eB
A Cryogenic Thermal Source for Detector Array Characterization
NASA Technical Reports Server (NTRS)
Chuss, David T.; Rostem, Karwan; Wollack, Edward J.; Berman, Leah; Colazo, Felipe; DeGeorge, Martin; Helson, Kyle; Sagliocca, Marco
2017-01-01
We describe the design, fabrication, and validation of a cryogenically compatible quasioptical thermal source for characterization of detector arrays. The source is constructed using a graphite-loaded epoxy mixture that is molded into a tiled pyramidal structure. The mold is fabricated using a hardened steel template produced via a wire electron discharge machining process. The absorptive mixture is bonded to a copper backplate enabling thermalization of the entire structure and measurement of the source temperature. Measurements indicate that the reflectance of the source is less than 0.001 across a spectral band extending from 75 to 330 gigahertz.
Li, Yang; Yang, Jianyi
2017-04-24
The prediction of protein-ligand binding affinity has recently been improved remarkably by machine-learning-based scoring functions. For example, using a set of simple descriptors representing the atomic distance counts, the RF-Score improves the Pearson correlation coefficient to about 0.8 on the core set of the PDBbind 2007 database, which is significantly higher than the performance of any conventional scoring function on the same benchmark. A few studies have been made to discuss the performance of machine-learning-based methods, but the reason for this improvement remains unclear. In this study, by systemically controlling the structural and sequence similarity between the training and test proteins of the PDBbind benchmark, we demonstrate that protein structural and sequence similarity makes a significant impact on machine-learning-based methods. After removal of training proteins that are highly similar to the test proteins identified by structure alignment and sequence alignment, machine-learning-based methods trained on the new training sets do not outperform the conventional scoring functions any more. On the contrary, the performance of conventional functions like X-Score is relatively stable no matter what training data are used to fit the weights of its energy terms.
View north of inside machine shop 36; shop floor accommodates ...
View north of inside machine shop 36; shop floor accommodates lathes capable of machining a cylinder 60 inches in diameter and 75 feet long; other equipment includes horizontal and vertical jig borders, hydraulic tube straighteners and other equipment for precision machining of large ship components. - Naval Base Philadelphia-Philadelphia Naval Shipyard, Structure Shop, League Island, Philadelphia, Philadelphia County, PA
Can Machine Scoring Deal with Broad and Open Writing Tests as Well as Human Readers?
ERIC Educational Resources Information Center
McCurry, Doug
2010-01-01
This article considers the claim that machine scoring of writing test responses agrees with human readers as much as humans agree with other humans. These claims about the reliability of machine scoring of writing are usually based on specific and constrained writing tasks, and there is reason for asking whether machine scoring of writing requires…
Confabulation Based Sentence Completion for Machine Reading
2010-11-01
making sentence completion an indispensible component of machine reading. Cogent confabulation is a bio-inspired computational model that mimics the...thus making sentence completion an indispensible component of machine reading. Cogent confabulation is a bio-inspired computational model that mimics...University Press, 1992. [2] H. Motoda and K. Yoshida, “Machine learning techniques to make computers easier to use,” Proceedings of the Fifteenth
Machine learning and radiology.
Wang, Shijun; Summers, Ronald M
2012-07-01
In this paper, we give a short introduction to machine learning and survey its applications in radiology. We focused on six categories of applications in radiology: medical image segmentation, registration, computer aided detection and diagnosis, brain function or activity analysis and neurological disease diagnosis from fMR images, content-based image retrieval systems for CT or MRI images, and text analysis of radiology reports using natural language processing (NLP) and natural language understanding (NLU). This survey shows that machine learning plays a key role in many radiology applications. Machine learning identifies complex patterns automatically and helps radiologists make intelligent decisions on radiology data such as conventional radiographs, CT, MRI, and PET images and radiology reports. In many applications, the performance of machine learning-based automatic detection and diagnosis systems has shown to be comparable to that of a well-trained and experienced radiologist. Technology development in machine learning and radiology will benefit from each other in the long run. Key contributions and common characteristics of machine learning techniques in radiology are discussed. We also discuss the problem of translating machine learning applications to the radiology clinical setting, including advantages and potential barriers. Copyright © 2012. Published by Elsevier B.V.
NASA Astrophysics Data System (ADS)
Zhang, Chupeng; Zhao, Huiying; Zhu, Xueliang; Zhao, Shijie; Jiang, Chunye
2018-01-01
The chemical mechanical polishing (CMP) is a key process during the machining route of plane optics. To improve the polishing efficiency and accuracy, a CMP model and machine tool were developed. Based on the Preston equation and the axial run-out error measurement results of the m circles on the tin plate, a CMP model that could simulate the material removal at any point on the workpiece was presented. An analysis of the model indicated that lower axial run-out error led to lower material removal but better polishing efficiency and accuracy. Based on this conclusion, the CMP machine was designed, and the ultraprecision gas hydrostatic guideway and rotary table as well as the Siemens 840Dsl numerical control system were incorporated in the CMP machine. To verify the design principles of machine, a series of detection and machining experiments were conducted. The LK-G5000 laser sensor was employed for detecting the straightness error of the gas hydrostatic guideway and the axial run-out error of the gas hydrostatic rotary table. A 300-mm-diameter optic was chosen for the surface profile machining experiments performed to determine the CMP efficiency and accuracy.
[Card-based age control mechanisms at tobacco vending machines. Effect and consequences].
Schneider, S; Meyer, C; Löber, S; Röhrig, S; Solle, D
2010-02-01
Until recently, 700,000 tobacco vending machines provided uncontrolled access to cigarettes for children and adolescents in Germany. On January 1, 2007, a card-based electronic locking device was attached to all tobacco vending machines to prevent the purchase of cigarettes by children and adolescents under 16. Starting in 2009, only persons older than 18 are able to buy cigarettes from tobacco vending machines. The aim of the present investigation (SToP Study: "Sources of Tobacco for Pupils" Study) was to assess changes in the number of tobacco vending machines after the introduction of these new technical devices (supplier's reaction). In addition, the ways smoking adolescents make purchases were assessed (consumer's reaction). We registered and mapped the total number of tobacco points of sale (tobacco POS) before and after the introduction of the card-based electronic locking device in two selected districts of the city of Cologne. Furthermore, pupils from local schools (response rate: 83%) were asked about their tobacco consumption and ways of purchase using a questionnaire. Results indicated that in the area investigated the total number of tobacco POSs decreased from 315 in 2005 to 277 in 2007. The rates of decrease were 48% for outdoor vending machines and 8% for indoor vending machines. Adolescents reported circumventing the card-based electronic locking devices (e.g., by using cards from older friends) and using other tobacco POSs (especially newspaper kiosks) or relying on their social network (mainly friends). The decreasing number of tobacco vending machines has not had a significant impact on cigarette acquisition by adolescent smokers as they tend to circumvent the newly introduced security measures.
A defect-driven diagnostic method for machine tool spindles
Vogl, Gregory W.; Donmez, M. Alkan
2016-01-01
Simple vibration-based metrics are, in many cases, insufficient to diagnose machine tool spindle condition. These metrics couple defect-based motion with spindle dynamics; diagnostics should be defect-driven. A new method and spindle condition estimation device (SCED) were developed to acquire data and to separate system dynamics from defect geometry. Based on this method, a spindle condition metric relying only on defect geometry is proposed. Application of the SCED on various milling and turning spindles shows that the new approach is robust for diagnosing the machine tool spindle condition. PMID:28065985
Investigation of gastric cancers in nude mice using X-ray in-line phase contrast imaging
2014-01-01
Background This paper is to report the new imaging of gastric cancers without the use of imaging agents. Both gastric normal regions and gastric cancer regions can be distinguished by using the principal component analysis (PCA) based on the gray level co-occurrence matrix (GLCM). Methods Human gastric cancer BGC823 cells were implanted into the stomachs of nude mice. Then, 3, 5, 7, 9 or 11 days after cancer cells implantation, the nude mice were sacrificed and their stomachs were removed. X-ray in-line phase contrast imaging (XILPCI), an X-ray phase contrast imaging method, has greater soft tissue contrast than traditional absorption radiography and generates higher-resolution images. The gastric specimens were imaged by an XILPCIs’ charge coupled device (CCD) of 9 μm image resolution. The PCA of the projective images’ region of interests (ROIs) based on GLCM were extracted to discriminate gastric normal regions and gastric cancer regions. Different stages of gastric cancers were classified by using support vector machines (SVMs). Results The X-ray in-line phase contrast images of nude mice gastric specimens clearly show the gastric architectures and the details of the early gastric cancers. The phase contrast computed tomography (CT) images of nude mice gastric cancer specimens are better than the traditional absorption CT images without the use of imaging agents. The results of the PCA of the texture parameters based on GLCM of normal regions is (F1 + F2) > 8.5, but those of cancer regions is (F1 + F2) < 8.5. The classification accuracy is 83.3% that classifying gastric specimens into different stages using SVMs. Conclusions This is a very preliminary feasibility study. With further researches, XILPCI could become a noninvasive method for future the early detection of gastric cancers or medical researches. PMID:25060352
High-speed machining of Space Shuttle External Tank (ET) panels
NASA Technical Reports Server (NTRS)
Miller, J. A.
1983-01-01
Potential production rates and project cost savings achieved by converting the conventional machining process in manufacturing shuttle external tank panels to high speed machining (HSM) techniques were studied. Savings were projected from the comparison of current production rates with HSM rates and with rates attainable on new conventional machines. The HSM estimates were also based on rates attainable by retrofitting existing conventional equipment with high speed spindle motors and rates attainable using new state of the art machines designed and built for HSM.
ERIC Educational Resources Information Center
Texas State Technical Coll., Waco.
This document is intended to help education and training institutions deliver the Machine Tool Advanced Skills Technology (MAST) curriculum to a variety of individuals and organizations. MAST consists of industry-specific skill standards and model curricula for 15 occupational specialty areas within the U.S. machine tool and metals-related…
ERIC Educational Resources Information Center
Texas State Technical Coll., Waco.
This document is intended to help education and training institutions deliver the Machine Tool Advanced Skills Technology (MAST) curriculum to a variety of individuals and organizations. MAST consists of industry-specific skill standards and model curricula for 15 occupational specialty areas within the U.S. machine tool and metals-related…
Evidence of end-effector based gait machines in gait rehabilitation after CNS lesion.
Hesse, S; Schattat, N; Mehrholz, J; Werner, C
2013-01-01
A task-specific repetitive approach in gait rehabilitation after CNS lesion is well accepted nowadays. To ease the therapists' and patients' physical effort, the past two decades have seen the introduction of gait machines to intensify the amount of gait practice. Two principles have emerged, an exoskeleton- and an endeffector-based approach. Both systems share the harness and the body weight support. With the end-effector-based devices, the patients' feet are positioned on two foot plates, whose movements simulate stance and swing phase. This article provides an overview on the end-effector based machine's effectiveness regarding the restoration of gait. For the electromechanical gait trainer GT I, a meta analysis identified nine controlled trials (RCT) in stroke subjects (n = 568) and were analyzed to detect differences between end-effector-based locomotion + physiotherapy and physiotherapy alone. Patients practising with the machine effected in a superior gait ability (210 out of 319 patients, 65.8% vs. 96 out of 249 patients, 38.6%, respectively, Z = 2.29, p = 0.020), due to a larger training intensity. Only single RCTs have been reported for other devices and etiologies. The introduction of end-effector based gait machines has opened a new succesful chapter in gait rehabilitation after CNS lesion.
Analytical Model-Based Design Optimization of a Transverse Flux Machine
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hasan, Iftekhar; Husain, Tausif; Sozer, Yilmaz
This paper proposes an analytical machine design tool using magnetic equivalent circuit (MEC)-based particle swarm optimization (PSO) for a double-sided, flux-concentrating transverse flux machine (TFM). The magnetic equivalent circuit method is applied to analytically establish the relationship between the design objective and the input variables of prospective TFM designs. This is computationally less intensive and more time efficient than finite element solvers. A PSO algorithm is then used to design a machine with the highest torque density within the specified power range along with some geometric design constraints. The stator pole length, magnet length, and rotor thickness are the variablesmore » that define the optimization search space. Finite element analysis (FEA) was carried out to verify the performance of the MEC-PSO optimized machine. The proposed analytical design tool helps save computation time by at least 50% when compared to commercial FEA-based optimization programs, with results found to be in agreement with less than 5% error.« less
TEACHING PHYSICS: A computer-based revitalization of Atwood's machine
NASA Astrophysics Data System (ADS)
Trumper, Ricardo; Gelbman, Moshe
2000-09-01
Atwood's machine is used in a microcomputer-based experiment to demonstrate Newton's second law with considerable precision. The friction force on the masses and the moment of inertia of the pulley can also be estimated.
NASA Astrophysics Data System (ADS)
Matras, A.; Kowalczyk, R.
2014-11-01
The analysis results of machining accuracy after the free form surface milling simulations (based on machining EN AW- 7075 alloys) for different machining strategies (Level Z, Radial, Square, Circular) are presented in the work. Particular milling simulations were performed using CAD/CAM Esprit software. The accuracy of obtained allowance is defined as a difference between the theoretical surface of work piece element (the surface designed in CAD software) and the machined surface after a milling simulation. The difference between two surfaces describes a value of roughness, which is as the result of tool shape mapping on the machined surface. Accuracy of the left allowance notifies in direct way a surface quality after the finish machining. Described methodology of usage CAD/CAM software can to let improve a time design of machining process for a free form surface milling by a 5-axis CNC milling machine with omitting to perform the item on a milling machine in order to measure the machining accuracy for the selected strategies and cutting data.
Machine Translation in Post-Contemporary Era
ERIC Educational Resources Information Center
Lin, Grace Hui Chin
2010-01-01
This article focusing on translating techniques via personal computer or laptop reports updated artificial intelligence progresses before 2010. Based on interpretations and information for field of MT [Machine Translation] by Yorick Wilks' book, "Machine Translation, Its scope and limits," this paper displays understandable theoretical frameworks…
Hybrid Power Management for Office Equipment
NASA Astrophysics Data System (ADS)
Gingade, Ganesh P.
Office machines (such as printers, scanners, fax, and copiers) can consume significant amounts of power. Few studies have been devoted to power management of office equipment. Most office machines have sleep modes to save power. Power management of these machines are usually timeout-based: a machine sleeps after being idle long enough. Setting the timeout duration can be difficult: if it is too long, the machine wastes power during idleness. If it is too short, the machine sleeps too soon and too often--the wakeup delay can significantly degrade productivity. Thus, power management is a tradeoff between saving energy and keeping short response time. Many power management policies have been published and one policy may outperform another in some scenarios. There is no definite conclusion which policy is always better. This thesis describes two methods for office equipment power management. The first method adaptively reduces power based on a constraint of the wakeup delay. The second method is a hybrid with multiple candidate policies and it selects the most appropriate power management policy. Using six months of request traces from 18 different offices, we demonstrate that the hybrid policy outperforms individual policies. We also discover that power management based on business hours does not produce consistent energy savings.
Absorption of zinc from lupin (Lupinus angustifolius)-based foods.
Petterson, D S; Sandström, B; Cederblad, A
1994-12-01
The absorption of Zn from a lupin (Lupinus angustifolius) milk fortified with Ca, a bread containing lupin flour (230 g/kg), a sauce containing lupin flour and a sauce containing a lupin-protein isolate was determined in humans by measuring the whole-body retention of radioisotope from meals labelled with 0.02 MBq 65Zn, allowing for endogenous excretion of Zn, after 14 d. The absorption of Zn from the Ca-enriched milk (16.2%) and the bread made with lupin flour (27.0%) was similar to literature figures for comparable soya-bean products. The absorption from composite meals made with lupin flour (28.2%) and protein isolate (32.7%) was significantly higher than that reported for comparable soya-bean products. In a second experiment the absorption of Zn from a lupin-milk base and a soya-bean-milk base was compared with that from Ca-supplemented bases. The absorption of Zn from the lupin-milk base (26.3%) was significantly higher than from the soya-bean-milk base (17.6%), and neither was significantly altered by the addition of Ca. Overall the absorption of Zn from lupin-protein foods was found to be higher than from comparable soya-bean products. Lupin milk could be an attractive alternative to soya-bean milk for infant formulas.
A microcomputer network for control of a continuous mining machine
DOE Office of Scientific and Technical Information (OSTI.GOV)
Schiffbauer, W.H.
1993-12-31
This report details a microcomputer-based control and monitoring network that was developed in-house by the U.S. Bureau of Mines and installed on a continuous mining machine. The network consists of microcomputers that are connected together via a single twisted-pair cable. Each microcomputer was developed to provide a particular function in the control process. Machine-mounted microcomputers, in conjunction with the appropriate sensors, provide closed-loop control of the machine, navigation, and environmental monitoring. Off-the-machine microcomputers provide remote control of the machine, sensor status, and a connection to the network so that external computers can access network data and control the continuous miningmore » machine. Because of the network`s generic structure, it can be installed on most mining machines.« less
75 FR 48954 - Arbitration Panel Decision Under the Randolph-Sheppard Act
Federal Register 2010, 2011, 2012, 2013, 2014
2010-08-12
... and its implementing regulations concerning the food services at Wright-Patterson Air Force Base in... permit to operate snack and beverage vending machines throughout the Wright-Patterson Air Force Base, and... income from the vending machines at the Wright-Patterson Air Force Base pursuant to the Act and...
Effect of Moisture Content of Paper Material on Laser Cutting
NASA Astrophysics Data System (ADS)
Stepanov, Alexander; Saukkonen, Esa; Piili, Heidi; Salminen, Antti
Laser technology has been used in industrial processes for several decades. The most advanced development and implementation took place in laser welding and cutting of metals in automotive and ship building industries. However, there is high potential to apply laser processing to other materials in various industrial fields. One of these potential fields could be paper industry to fulfill the demand for high quality, fast and reliable cutting technology. Difficulties in industrial application of laser cutting for paper industry are associated to lack of basic information, awareness of technology and its application possibilities. Nowadays possibilities of using laser cutting for paper materials are widened and high automation level of equipment has made this technology more interesting for manufacturing processes. Promising area of laser cutting application at paper making machines is longitudinal cutting of paper web (edge trimming). There are few locations at a paper making machine where edge trimming is usually done: wet press section, calender or rewinder. Paper web is characterized with different moisture content at different points of the paper making machine. The objective of this study was to investigate the effect of moisture content of paper material on laser cutting parameters. Effect of moisture content on cellulose fibers, laser absorption and energy needed for cutting is described as well. Laser cutting tests were carried out using CO2 laser.
A Distributed Data Base Version of INGRES.
ERIC Educational Resources Information Center
Stonebraker, Michael; Neuhold, Eric
Extensions are required to the currently operational INGRES data base system for it to manage a data base distributed over multiple machines in a computer network running the UNIX operating system. Three possible user views include: (1) each relation in a unique machine, (2) a user interaction with the data base which can only span relations at a…
Efficient Embedded Decoding of Neural Network Language Models in a Machine Translation System.
Zamora-Martinez, Francisco; Castro-Bleda, Maria Jose
2018-02-22
Neural Network Language Models (NNLMs) are a successful approach to Natural Language Processing tasks, such as Machine Translation. We introduce in this work a Statistical Machine Translation (SMT) system which fully integrates NNLMs in the decoding stage, breaking the traditional approach based on [Formula: see text]-best list rescoring. The neural net models (both language models (LMs) and translation models) are fully coupled in the decoding stage, allowing to more strongly influence the translation quality. Computational issues were solved by using a novel idea based on memorization and smoothing of the softmax constants to avoid their computation, which introduces a trade-off between LM quality and computational cost. These ideas were studied in a machine translation task with different combinations of neural networks used both as translation models and as target LMs, comparing phrase-based and [Formula: see text]-gram-based systems, showing that the integrated approach seems more promising for [Formula: see text]-gram-based systems, even with nonfull-quality NNLMs.
Models of filter-based particle light absorption measurements
NASA Astrophysics Data System (ADS)
Hamasha, Khadeejeh M.
Light absorption by aerosol is very important in the visible, near UN, and near I.R region of the electromagnetic spectrum. Aerosol particles in the atmosphere have a great influence on the flux of solar energy, and also impact health in a negative sense when they are breathed into lungs. Aerosol absorption measurements are usually performed by filter-based methods that are derived from the change in light transmission through a filter where particles have been deposited. These methods suffer from interference between light-absorbing and light-scattering aerosol components. The Aethalometer is the most commonly used filter-based instrument for aerosol light absorption measurement. This dissertation describes new understanding of aerosol light absorption obtained by the filter method. The theory uses a multiple scattering model for the combination of filter and particle optics. The theory is evaluated using Aethalometer data from laboratory and ambient measurements in comparison with photoacoustic measurements of aerosol light absorption. Two models were developed to calculate aerosol light absorption coefficients from the Aethalometer data, and were compared to the in-situ aerosol light absorption coefficients. The first is an approximate model and the second is a "full" model. In the approximate model two extreme cases of aerosol optics were used to develop a model-based calibration scheme for the 7-wavelength Aethalometer. These cases include those of very strong scattering aerosols (Ammonium sulfate sample) and very absorbing aerosols (kerosene soot sample). The exponential behavior of light absorption in the strong multiple scattering limit is shown to be the square root of the total absorption optical depth rather than linear with optical depth as is commonly assumed with Beer's law. 2-stream radiative transfer theory was used to develop the full model to calculate the aerosol light absorption coefficients from the Aethalometer data. This comprehensive model allows for studying very general cases of particles of various sizes embedded on arbitrary filter media. Application of this model to the Reno Aerosol Optics Study (Laboratory data) shows that the aerosol light absorption coefficients are about half of the Aethalometer attenuation coefficients, and there is a reasonable agreement between the model calculated absorption coefficients at 521 nm and the measured photoacoustic absorption coefficients at 532 nm. For ambient data obtained during the Las Vegas study, it shows that the model absorption coefficients at 521 nm are larger than the photoacoustic coefficients at 532 nm. Use of the 2-stream model shows that particle penetration depth into the filter has a strong influence on the interpretation of filter-based aerosol light absorption measurements. This is likely explanation for the difference found between model results for filter-based aerosol light absorption and those from photoacoustic measurements for ambient and laboratory aerosol.
Initial planetary base construction techniques and machine implementation
NASA Technical Reports Server (NTRS)
Crockford, William W.
1987-01-01
Conceptual designs of (1) initial planetary base structures, and (2) an unmanned machine to perform the construction of these structures using materials local to the planet are presented. Rock melting is suggested as a possible technique to be used by the machine in fabricating roads, platforms, and interlocking bricks. Identification of problem areas in machine design and materials processing is accomplished. The feasibility of the designs is contingent upon favorable results of an analysis of the engineering behavior of the product materials. The analysis requires knowledge of several parameters for solution of the constitutive equations of the theory of elasticity. An initial collection of these parameters is presented which helps to define research needed to perform a realistic feasibility study. A qualitative approach to estimating power and mass lift requirements for the proposed machine is used which employs specifications of currently available equipment. An initial, unmanned mission scenario is discussed with emphasis on identifying uncompleted tasks and suggesting design considerations for vehicles and primitive structures which use the products of the machine processing.
Performance study of a data flow architecture
NASA Technical Reports Server (NTRS)
Adams, George
1985-01-01
Teams of scientists studied data flow concepts, static data flow machine architecture, and the VAL language. Each team mapped its application onto the machine and coded it in VAL. The principal findings of the study were: (1) Five of the seven applications used the full power of the target machine. The galactic simulation and multigrid fluid flow teams found that a significantly smaller version of the machine (16 processing elements) would suffice. (2) A number of machine design parameters including processing element (PE) function unit numbers, array memory size and bandwidth, and routing network capability were found to be crucial for optimal machine performance. (3) The study participants readily acquired VAL programming skills. (4) Participants learned that application-based performance evaluation is a sound method of evaluating new computer architectures, even those that are not fully specified. During the course of the study, participants developed models for using computers to solve numerical problems and for evaluating new architectures. These models form the bases for future evaluation studies.
Nässelqvist, Mattias; Gustavsson, Rolf; Aidanpää, Jan-Olov
2013-07-01
It is important to monitor the radial loads in hydropower units in order to protect the machine from harmful radial loads. Existing recommendations in the standards regarding the radial movements of the shaft and bearing housing in hydropower units, ISO-7919-5 (International Organization for Standardization, 2005, "ISO 7919-5: Mechanical Vibration-Evaluation of Machine Vibration by Measurements on Rotating Shafts-Part 5: Machine Sets in Hydraulic Power Generating and Pumping Plants," Geneva, Switzerland) and ISO-10816-5 (International Organization for Standardization, 2000, "ISO 10816-5: Mechanical Vibration-Evaluation of Machine Vibration by Measurements on Non-Rotating Parts-Part 5: Machine Sets in Hydraulic Power Generating and Pumping Plants," Geneva, Switzerland), have alarm levels based on statistical data and do not consider the mechanical properties of the machine. The synchronous speed of the unit determines the maximum recommended shaft displacement and housing acceleration, according to these standards. This paper presents a methodology for the alarm and trip levels based on the design criteria of the hydropower unit and the measured radial loads in the machine during operation. When a hydropower unit is designed, one of its design criteria is to withstand certain loads spectra without the occurrence of fatigue in the mechanical components. These calculated limits for fatigue are used to set limits for the maximum radial loads allowed in the machine before it shuts down in order to protect itself from damage due to high radial loads. Radial loads in hydropower units are caused by unbalance, shape deviations, dynamic flow properties in the turbine, etc. Standards exist for balancing and manufacturers (and power plant owners) have recommendations for maximum allowed shape deviations in generators. These standards and recommendations determine which loads, at a maximum, should be allowed before an alarm is sent that the machine needs maintenance. The radial bearing load can be determined using load cells, bearing properties multiplied by shaft displacement, or bearing bracket stiffness multiplied by housing compression or movement. Different load measurement methods should be used depending on the design of the machine and accuracy demands in the load measurement. The methodology presented in the paper is applied to a 40 MW hydropower unit; suggestions are presented for the alarm and trip levels for the machine based on the mechanical properties and radial loads.
Microcomputer network for control of a continuous mining machine. Information circular/1993
DOE Office of Scientific and Technical Information (OSTI.GOV)
Schiffbauer, W.H.
1993-01-01
The paper details a microcomputer-based control and monitoring network that was developed in-house by the U.S. Bureau of Mines, and installed on a Joy 14 continuous mining machine. The network consists of microcomputers that are connected together via a single twisted pair cable. Each microcomputer was developed to provide a particular function in the control process. Machine-mounted microcomputers in conjunction with the appropriate sensors provide closed-loop control of the machine, navigation, and environmental monitoring. Off-the-machine microcomputers provide remote control of the machine, sensor status, and a connection to the network so that external computers can access network data and controlmore » the continuous mining machine. Although the network was installed on a Joy 14 continuous mining machine, its use extends beyond it. Its generic structure lends itself to installation onto most mining machine types.« less
Speckle-learning-based object recognition through scattering media.
Ando, Takamasa; Horisaki, Ryoichi; Tanida, Jun
2015-12-28
We experimentally demonstrated object recognition through scattering media based on direct machine learning of a number of speckle intensity images. In the experiments, speckle intensity images of amplitude or phase objects on a spatial light modulator between scattering plates were captured by a camera. We used the support vector machine for binary classification of the captured speckle intensity images of face and non-face data. The experimental results showed that speckles are sufficient for machine learning.
A New Type of Tea Baking Machine Based on Pro/E Design
NASA Astrophysics Data System (ADS)
Lin, Xin-Ying; Wang, Wei
2017-11-01
In this paper, the production process of wulong tea was discussed, mainly the effect of baking on the quality of tea. The suitable baking temperature of different tea was introduced. Based on Pro/E, a new type of baking machine suitable for wulong tea baking was designed. The working principle, mechanical structure and constant temperature timing intelligent control system of baking machine were expounded. Finally, the characteristics and innovation of new baking machine were discussed.The mechanical structure of this baking machine is more simple and reasonable, and can use the heat of the inlet and outlet, more energy saving and environmental protection. The temperature control part adopts fuzzy PID control, which can improve the accuracy and response speed of temperature control and reduce the dependence of baking operation on skilled experience.
Research on electrodischarge drilling of polycrystalline diamond with increased gap voltage
NASA Astrophysics Data System (ADS)
Skoczypiec, Sebastian; Bizoń, Wojciech; Żyra, Agnieszka
2018-05-01
This paper presents an experimental investigation of the machining characteristics of polycrystalline diamond (PCD). Machining of PCD by conventional technologies is not an effective solution. Due to presence of cobalt this material can be machined by application of electrical discharges. On the other side, electrical conductivity of PCD is on the limit of electrodischarge machining (EDM) possibilities. Proposed paper reports experimental investigation on electrodischarge drilling of PCD samples. The test were carried out with application on of high-voltage (up to 550 V) pulse power unit for two kinds of dielectrics: carbon based (Exxsol D80) and de-ionized water. As output parameters machining accuracy (side gap), material removal rate were selected. Also, based on SEM photographs and energy dispersive X-ray spectroscopy (EDS) analysis, a qualitative evaluation of the obtained results was presented.
Applying machine learning to identify autistic adults using imitation: An exploratory study.
Li, Baihua; Sharma, Arjun; Meng, James; Purushwalkam, Senthil; Gowen, Emma
2017-01-01
Autism spectrum condition (ASC) is primarily diagnosed by behavioural symptoms including social, sensory and motor aspects. Although stereotyped, repetitive motor movements are considered during diagnosis, quantitative measures that identify kinematic characteristics in the movement patterns of autistic individuals are poorly studied, preventing advances in understanding the aetiology of motor impairment, or whether a wider range of motor characteristics could be used for diagnosis. The aim of this study was to investigate whether data-driven machine learning based methods could be used to address some fundamental problems with regard to identifying discriminative test conditions and kinematic parameters to classify between ASC and neurotypical controls. Data was based on a previous task where 16 ASC participants and 14 age, IQ matched controls observed then imitated a series of hand movements. 40 kinematic parameters extracted from eight imitation conditions were analysed using machine learning based methods. Two optimal imitation conditions and nine most significant kinematic parameters were identified and compared with some standard attribute evaluators. To our knowledge, this is the first attempt to apply machine learning to kinematic movement parameters measured during imitation of hand movements to investigate the identification of ASC. Although based on a small sample, the work demonstrates the feasibility of applying machine learning methods to analyse high-dimensional data and suggest the potential of machine learning for identifying kinematic biomarkers that could contribute to the diagnostic classification of autism.
Temperature Measurement and Numerical Prediction in Machining Inconel 718
Tapetado, Alberto; Vázquez, Carmen; Miguélez, Henar
2017-01-01
Thermal issues are critical when machining Ni-based superalloy components designed for high temperature applications. The low thermal conductivity and extreme strain hardening of this family of materials results in elevated temperatures around the cutting area. This elevated temperature could lead to machining-induced damage such as phase changes and residual stresses, resulting in reduced service life of the component. Measurement of temperature during machining is crucial in order to control the cutting process, avoiding workpiece damage. On the other hand, the development of predictive tools based on numerical models helps in the definition of machining processes and the obtainment of difficult to measure parameters such as the penetration of the heated layer. However, the validation of numerical models strongly depends on the accurate measurement of physical parameters such as temperature, ensuring the calibration of the model. This paper focuses on the measurement and prediction of temperature during the machining of Ni-based superalloys. The temperature sensor was based on a fiber-optic two-color pyrometer developed for localized temperature measurements in turning of Inconel 718. The sensor is capable of measuring temperature in the range of 250 to 1200 °C. Temperature evolution is recorded in a lathe at different feed rates and cutting speeds. Measurements were used to calibrate a simplified numerical model for prediction of temperature fields during turning. PMID:28665312
Cutting and drilling of carbon fiber reinforced plastics (CFRP) by 70W short pulse nanosecond laser
NASA Astrophysics Data System (ADS)
Jaeschke, Peter; Stolberg, Klaus; Bastick, Stefan; Ziolkowski, Ewa; Roehner, Markus; Suttmann, Oliver; Overmeyer, Ludger
2014-02-01
Continuous carbon fibre reinforced plastics (CFRP) are recognized as having a significant lightweight construction potential for a wide variety of industrial applications. However, a today`s barrier for a comprehensive dissemination of CFRP structures is the lack of economic, quick and reliable manufacture processes, e.g. the cutting and drilling steps. In this paper, the capability of using pulsed disk lasers in CFRP machining is discussed. In CFRP processing with NIR lasers, carbon fibers show excellent optical absorption and heat dissipation, contrary to the plastics matrix. Therefore heat dissipation away from the laser focus into the material is driven by heat conduction of the fibres. The matrix is heated indirectly by heat transfer from the fibres. To cut CFRP, it is required to reach the melting temperature for thermoplastic matrix materials or the disintegration temperature for thermoset systems as well as the sublimation temperature of the reinforcing fibers simultaneously. One solution for this problem is to use short pulse nanosecond lasers. We have investigated CFRP cutting and drilling with such a laser (max. 7 mJ @ 10 kHz, 30 ns). This laser offers the opportunity of wide range parameter tuning for systematic process optimization. By applying drilling and cutting operations based on galvanometer scanning techniques in multi-cycle mode, excellent surface and edge characteristics in terms of delamination-free and intact fiber-matrix interface were achieved. The results indicate that nanosecond disk laser machining could consequently be a suitable tool for the automotive and aircraft industry for cutting and drilling steps.
NASA Astrophysics Data System (ADS)
Triebel, W.; Mühlig, C.; Kufert, S.
2005-10-01
Precise absorption measurements of bulk materials and coatings upon pulsed ArF laser irradiation are presented using a compact experimental setup based on the laser induced deflection technique (LID). For absorption measurements of bulk materials the influence of pure bulk and pure surface absorption on the temperature and refractive index profile and thus for the probe beam deflection is analyzed in detail. The separation of bulk and surface absorption via the commonly used variation of the sample thickness is carried out for fused silica and calcium fluoride. The experimental results show that for the given surface polishing quality the bulk absorption coefficient of fused silica can be obtained by investigating only one sample. To avoid the drawback of different bulk and surface properties amongst a thickness series, we propose a strategy based on the LID technique to generally obtain surface and bulk absorption separately by investigating only one sample. Apart from measuring bulk absorption coefficients the LID technique is applied to determine the absorption of highly reflecting (HR) coatings on CaF2 substrates. Beside the measuring strategy the experimental results of a AlF3/LaF3 based HR coating are presented. In order to investigate a larger variety of coatings, including high transmitting coatings, a general measuring strategy based on the LID technique is proposed.
A complete diet-based algorithm for predicting nonheme iron absorption in adults.
Armah, Seth M; Carriquiry, Alicia; Sullivan, Debra; Cook, James D; Reddy, Manju B
2013-07-01
Many algorithms have been developed in the past few decades to estimate nonheme iron absorption from the diet based on single meal absorption studies. Yet single meal studies exaggerate the effect of diet and other factors on absorption. Here, we propose a new algorithm based on complete diets for estimating nonheme iron absorption. We used data from 4 complete diet studies each with 12-14 participants for a total of 53 individuals (19 men and 34 women) aged 19-38 y. In each study, each participant was observed during three 1-wk periods during which they consumed different diets. The diets were typical, high, or low in meat, tea, calcium, or vitamin C. The total sample size was 159 (53 × 3) observations. We used multiple linear regression to quantify the effect of different factors on iron absorption. Serum ferritin was the most important factor in explaining differences in nonheme iron absorption, whereas the effect of dietary factors was small. When our algorithm was validated with single meal and complete diet data, the respective R(2) values were 0.57 (P < 0.001) and 0.84 (P < 0.0001). The results also suggest that between-person variations explain a large proportion of the differences in nonheme iron absorption. The algorithm based on complete diets we propose is useful for predicting nonheme iron absorption from the diets of different populations.
Research on axisymmetric aspheric surface numerical design and manufacturing technology
NASA Astrophysics Data System (ADS)
Wang, Zhen-zhong; Guo, Yin-biao; Lin, Zheng
2006-02-01
The key technology for aspheric machining offers exact machining path and machining aspheric lens with high accuracy and efficiency, in spite of the development of traditional manual manufacturing into nowadays numerical control (NC) machining. This paper presents a mathematical model between virtual cone and aspheric surface equations, and discusses the technology of uniform wear of grinding wheel and error compensation in aspheric machining. Finally, a software system for high precision aspheric surface manufacturing is designed and realized, based on the mentioned above. This software system can work out grinding wheel path according to input parameters and generate machining NC programs of aspheric surfaces.
NASA Astrophysics Data System (ADS)
Sigurdson, J.; Tagerud, J.
1986-05-01
A UNIDO publication about machine tools with automatic control discusses the following: (1) numerical control (NC) machine tool perspectives, definition of NC, flexible manufacturing systems, robots and their industrial application, research and development, and sensors; (2) experience in developing a capability in NC machine tools; (3) policy issues; (4) procedures for retrieval of relevant documentation from data bases. Diagrams, statistics, bibliography are included.
Wu, Dung-Sheng
2018-01-01
Spark-assisted chemical engraving (SACE) is a non-traditional machining technology that is used to machine electrically non-conducting materials including glass, ceramics, and quartz. The processing accuracy, machining efficiency, and reproducibility are the key factors in the SACE process. In the present study, a machine vision method is applied to monitor and estimate the status of a SACE-drilled hole in quartz glass. During the machining of quartz glass, the spring-fed tool electrode was pre-pressured on the quartz glass surface to feed the electrode that was in contact with the machining surface of the quartz glass. In situ image acquisition and analysis of the SACE drilling processes were used to analyze the captured image of the state of the spark discharge at the tip and sidewall of the electrode. The results indicated an association between the accumulative size of the SACE-induced spark area and deepness of the hole. The results indicated that the evaluated depths of the SACE-machined holes were a proportional function of the accumulative spark size with a high degree of correlation. The study proposes an innovative computer vision-based method to estimate the deepness and status of SACE-drilled holes in real time. PMID:29565303
Ho, Chao-Ching; Wu, Dung-Sheng
2018-03-22
Spark-assisted chemical engraving (SACE) is a non-traditional machining technology that is used to machine electrically non-conducting materials including glass, ceramics, and quartz. The processing accuracy, machining efficiency, and reproducibility are the key factors in the SACE process. In the present study, a machine vision method is applied to monitor and estimate the status of a SACE-drilled hole in quartz glass. During the machining of quartz glass, the spring-fed tool electrode was pre-pressured on the quartz glass surface to feed the electrode that was in contact with the machining surface of the quartz glass. In situ image acquisition and analysis of the SACE drilling processes were used to analyze the captured image of the state of the spark discharge at the tip and sidewall of the electrode. The results indicated an association between the accumulative size of the SACE-induced spark area and deepness of the hole. The results indicated that the evaluated depths of the SACE-machined holes were a proportional function of the accumulative spark size with a high degree of correlation. The study proposes an innovative computer vision-based method to estimate the deepness and status of SACE-drilled holes in real time.
The in-situ 3D measurement system combined with CNC machine tools
NASA Astrophysics Data System (ADS)
Zhao, Huijie; Jiang, Hongzhi; Li, Xudong; Sui, Shaochun; Tang, Limin; Liang, Xiaoyue; Diao, Xiaochun; Dai, Jiliang
2013-06-01
With the development of manufacturing industry, the in-situ 3D measurement for the machining workpieces in CNC machine tools is regarded as the new trend of efficient measurement. We introduce a 3D measurement system based on the stereovision and phase-shifting method combined with CNC machine tools, which can measure 3D profile of the machining workpieces between the key machining processes. The measurement system utilizes the method of high dynamic range fringe acquisition to solve the problem of saturation induced by specular lights reflected from shiny surfaces such as aluminum alloy workpiece or titanium alloy workpiece. We measured two workpieces of aluminum alloy on the CNC machine tools to demonstrate the effectiveness of the developed measurement system.
Motion Simulation Analysis of Rail Weld CNC Fine Milling Machine
NASA Astrophysics Data System (ADS)
Mao, Huajie; Shu, Min; Li, Chao; Zhang, Baojun
CNC fine milling machine is a new advanced equipment of rail weld precision machining with high precision, high efficiency, low environmental pollution and other technical advantages. The motion performance of this machine directly affects its machining accuracy and stability, which makes it an important consideration for its design. Based on the design drawings, this article completed 3D modeling of 60mm/kg rail weld CNC fine milling machine by using Solidworks. After that, the geometry was imported into Adams to finish the motion simulation analysis. The displacement, velocity, angular velocity and some other kinematical parameters curves of the main components were obtained in the post-processing and these are the scientific basis for the design and development for this machine.
View southwest of machine shops, building 18 section visible in ...
View southwest of machine shops, building 18 section visible in foreground; building 16 section on left. This structure consists of two formerly separate buildings. Jet Lowe, Haer staff photographer, summer 1995. - Naval Base Philadelphia-Philadelphia Naval Shipyard, Machine Shops, League Island, Philadelphia, Philadelphia County, PA
26 CFR 1.954-4 - Foreign base company services income.
Code of Federal Regulations, 2014 CFR
2014-04-01
... substantial assistance when taken together or in combination with other assistance furnished by a related... A is paid by related corporation M for the installation and maintenance of industrial machines which... manufactures an industrial machine which requires specialized installation. Corporation M sells the machines...
Automated generation and ensemble-learned matching of X-ray absorption spectra
NASA Astrophysics Data System (ADS)
Zheng, Chen; Mathew, Kiran; Chen, Chi; Chen, Yiming; Tang, Hanmei; Dozier, Alan; Kas, Joshua J.; Vila, Fernando D.; Rehr, John J.; Piper, Louis F. J.; Persson, Kristin A.; Ong, Shyue Ping
2018-12-01
X-ray absorption spectroscopy (XAS) is a widely used materials characterization technique to determine oxidation states, coordination environment, and other local atomic structure information. Analysis of XAS relies on comparison of measured spectra to reliable reference spectra. However, existing databases of XAS spectra are highly limited both in terms of the number of reference spectra available as well as the breadth of chemistry coverage. In this work, we report the development of XASdb, a large database of computed reference XAS, and an Ensemble-Learned Spectra IdEntification (ELSIE) algorithm for the matching of spectra. XASdb currently hosts more than 800,000 K-edge X-ray absorption near-edge spectra (XANES) for over 40,000 materials from the open-science Materials Project database. We discuss a high-throughput automation framework for FEFF calculations, built on robust, rigorously benchmarked parameters. FEFF is a computer program uses a real-space Green's function approach to calculate X-ray absorption spectra. We will demonstrate that the ELSIE algorithm, which combines 33 weak "learners" comprising a set of preprocessing steps and a similarity metric, can achieve up to 84.2% accuracy in identifying the correct oxidation state and coordination environment of a test set of 19 K-edge XANES spectra encompassing a diverse range of chemistries and crystal structures. The XASdb with the ELSIE algorithm has been integrated into a web application in the Materials Project, providing an important new public resource for the analysis of XAS to all materials researchers. Finally, the ELSIE algorithm itself has been made available as part of veidt, an open source machine-learning library for materials science.
NASA Astrophysics Data System (ADS)
Curran, S. J.; Duchesne, S. W.; Divoli, A.; Allison, J. R.
2016-11-01
The star-forming reservoir in the distant Universe can be detected through H I 21-cm absorption arising from either cool gas associated with a radio source or from within a galaxy intervening the sightline to the continuum source. In order to test whether the nature of the absorber can be predicted from the profile shape, we have compiled and analysed all of the known redshifted (z ≥ 0.1) H I 21-cm absorption profiles. Although between individual spectra there is too much variation to assign a typical spectral profile, we confirm that associated absorption profiles are, on average, wider than their intervening counterparts. It is widely hypothesized that this is due to high-velocity nuclear gas feeding the central engine, absent in the more quiescent intervening absorbers. Modelling the column density distribution of the mean associated and intervening spectra, we confirm that the additional low optical depth, wide dispersion component, typical of associated absorbers, arises from gas within the inner parsec. With regard to the potential of predicting the absorber type in the absence of optical spectroscopy, we have implemented machine learning techniques to the 55 associated and 43 intervening spectra, with each of the tested models giving a ≳ 80 per cent accuracy in the prediction of the absorber type. Given the impracticability of follow-up optical spectroscopy of the large number of 21-cm detections expected from the next generation of large radio telescopes, this could provide a powerful new technique with which to determine the nature of the absorbing galaxy.
Interior of building 16 section, view north of machine shop, ...
Interior of building 16 section, view north of machine shop, showing shrink-fitting a bearing sleeve onto a section of the propeller shaft for the aircraft carrier John F. Kennedy. The lathe on the extreme left of the photograph was used to machine bearing sleeves to final dimensions. This work, in August 1994, was the final major machine shop job done for the U.S. Navy. Photograph by Robert Stewart, August 1994. - Naval Base Philadelphia-Philadelphia Naval Shipyard, Machine Shops, League Island, Philadelphia, Philadelphia County, PA
Highly Productive Tools For Turning And Milling
NASA Astrophysics Data System (ADS)
Vasilko, Karol
2015-12-01
Beside cutting speed, shift is another important parameter of machining. Its considerable influence is shown mainly in the workpiece machined surface microgeometry. In practice, mainly its combination with the radius of cutting tool tip rounding is used. Options to further increase machining productivity and machined surface quality are hidden in this approach. The paper presents variations of the design of productive cutting tools for lathe work and milling on the base of the use of the laws of the relationship among the highest reached uneveness of machined surface, tool tip radius and shift.
Machine Learning Applications to Resting-State Functional MR Imaging Analysis.
Billings, John M; Eder, Maxwell; Flood, William C; Dhami, Devendra Singh; Natarajan, Sriraam; Whitlow, Christopher T
2017-11-01
Machine learning is one of the most exciting and rapidly expanding fields within computer science. Academic and commercial research entities are investing in machine learning methods, especially in personalized medicine via patient-level classification. There is great promise that machine learning methods combined with resting state functional MR imaging will aid in diagnosis of disease and guide potential treatment for conditions thought to be impossible to identify based on imaging alone, such as psychiatric disorders. We discuss machine learning methods and explore recent advances. Copyright © 2017 Elsevier Inc. All rights reserved.
NASA Astrophysics Data System (ADS)
Zhang, Huibin; Wang, Yuqiao; Chen, Haoran; Zhao, Yongli; Zhang, Jie
2017-12-01
In software defined optical networks (SDON), the centralized control plane may encounter numerous intrusion threatens which compromise the security level of provisioned services. In this paper, the issue of control plane security is studied and two machine-learning-based control plane intrusion detection techniques are proposed for SDON with properly selected features such as bandwidth, route length, etc. We validate the feasibility and efficiency of the proposed techniques by simulations. Results show an accuracy of 83% for intrusion detection can be achieved with the proposed machine-learning-based control plane intrusion detection techniques.
Study on Gap Flow Field Simulation in Small Hole Machining of Ultrasonic Assisted EDM
NASA Astrophysics Data System (ADS)
Liu, Yu; Chang, Hao; Zhang, Wenchao; Ma, Fujian; Sha, Zhihua; Zhang, Shengfang
2017-12-01
When machining a small hole with high aspect ratio in EDM, it is hard for the flushing liquid entering the bottom gap and the debris could hardly be removed, which results in the accumulation of debris and affects the machining efficiency and machining accuracy. The assisted ultrasonic vibration can improve the removal of debris in the gap. Based on dynamics simulation software Fluent, a 3D model of debris movement in the gap flow field of EDM small hole machining assisted with side flushing and ultrasonic vibration is established in this paper. When depth to ratio is 3, the laws of different amplitudes and frequencies on debris distribution and removal are quantitatively analysed. The research results show that periodic ultrasonic vibration can promote the movement of debris, which is beneficial to the removal of debris in the machining gap. Compared to traditional small hole machining in EDM, the debris in the machining gap is greatly reduced, which ensures the stability of machining process and improves the machining efficiency.
Embedded Real-Time Linux for Instrument Control and Data Logging
NASA Technical Reports Server (NTRS)
Clanton, Sam; Gore, Warren J. (Technical Monitor)
2002-01-01
When I moved to the west. coast to take a job at NASA's Ames Research Center in Mountain View, CA, I was impressed with the variety of equipment and software which scientists at the center use to conduct their research. was happy to find that I was just as likely to see a machine running Lenox as one running Windows in the offices and laboratories of NASA Ames (although many people seem to use Moos around here). I was especially happy to find that the particular group with whom I was going to work, the Atmospheric Physics Branch at Ames, relied almost entirely on Lenox machines for their day-to-day work. So it was no surprise that when it was time to construct a new control system for one of their most important pieces of hardware, a switch from an unpredictable DOS-based platform to an Embedded Linux-based one was a decision easily made. The system I am working on is called the Solar Spectral Flux Radiometer (SSFR), a PC-104 based system custom-built by Dr. Warren Gore at Ames. Dr. Gore, Dr. Peter Pilewskie, Dr. Maura Robberies and Larry Pezzolo use the SSFR in their research. The team working on the controller project consists of Dr. Gore, John Pommier, and myself. The SSFR is used by the ,cities Atmospheric Radiation Group to measure solar spectral irradiance at moderate resolution to determine the radiative effect of clouds, aerosols, and gases on climate, and also to infer the physical properties of aerosols and clouds. Two identical SSFR's have been built and successfully deployed in three field missions: 1) the Department of Energy Atmospheric Radiation Measurement (ARM) Enhanced Shortwave Experiment (ARESE) II in February/March, 2000; 2) the Puerto Rico Dust Experiment (PRIDE) in July, 2000; and 3) the South African Regional Science Initiative (SAFARI) in August/September, 2000. Additionally, the SSFR was used to acquire water vapor spectra using the Ames Diameter base-path multiple-reflection absorption cell in a laboratory experiment.
Electric machine differential for vehicle traction control and stability control
NASA Astrophysics Data System (ADS)
Kuruppu, Sandun Shivantha
Evolving requirements in energy efficiency and tightening regulations for reliable electric drivetrains drive the advancement of the hybrid electric (HEV) and full electric vehicle (EV) technology. Different configurations of EV and HEV architectures are evaluated for their performance. The future technology is trending towards utilizing distinctive properties in electric machines to not only to improve efficiency but also to realize advanced road adhesion controls and vehicle stability controls. Electric machine differential (EMD) is such a concept under current investigation for applications in the near future. Reliability of a power train is critical. Therefore, sophisticated fault detection schemes are essential in guaranteeing reliable operation of a complex system such as an EMD. The research presented here emphasize on implementation of a 4kW electric machine differential, a novel single open phase fault diagnostic scheme, an implementation of a real time slip optimization algorithm and an electric machine differential based yaw stability improvement study. The proposed d-q current signature based SPO fault diagnostic algorithm detects the fault within one electrical cycle. The EMD based extremum seeking slip optimization algorithm reduces stopping distance by 30% compared to hydraulic braking based ABS.
Effect of the Machining Processes on Low Cycle Fatigue Behavior of a Powder Metallurgy Disk
NASA Technical Reports Server (NTRS)
Telesman, J.; Kantzos, P.; Gabb, T. P.; Ghosn, L. J.
2010-01-01
A study has been performed to investigate the effect of various machining processes on fatigue life of configured low cycle fatigue specimens machined out of a NASA developed LSHR P/M nickel based disk alloy. Two types of configured specimen geometries were employed in the study. To evaluate a broach machining processes a double notch geometry was used with both notches machined using broach tooling. EDM machined notched specimens of the same configuration were tested for comparison purposes. Honing finishing process was evaluated by using a center hole specimen geometry. Comparison testing was again done using EDM machined specimens of the same geometry. The effect of these machining processes on the resulting surface roughness, residual stress distribution and microstructural damage were characterized and used in attempt to explain the low cycle fatigue results.
The Impact Of Surface Shape Of Chip-Breaker On Machined Surface
NASA Astrophysics Data System (ADS)
Šajgalík, Michal; Czán, Andrej; Martinček, Juraj; Varga, Daniel; Hemžský, Pavel; Pitela, David
2015-12-01
Machined surface is one of the most used indicators of workpiece quality. But machined surface is influenced by several factors such as cutting parameters, cutting material, shape of cutting tool or cutting insert, micro-structure of machined material and other known as technological parameters. By improving of these parameters, we can improve machined surface. In the machining, there is important to identify the characteristics of main product of these processes - workpiece, but also the byproduct - the chip. Size and shape of chip has impact on lifetime of cutting tools and its inappropriate form can influence the machine functionality and lifetime, too. This article deals with elimination of long chip created when machining of shaft in automotive industry and with impact of shape of chip-breaker on shape of chip in various cutting conditions based on production requirements.
Decomposition of the compound Atwood machine
NASA Astrophysics Data System (ADS)
Lopes Coelho, R.
2017-11-01
Non-standard solving strategies for the compound Atwood machine problem have been proposed. The present strategy is based on a very simple idea. Taking an Atwood machine and replacing one of its bodies by another Atwood machine, we have a compound machine. As this operation can be repeated, we can construct any compound Atwood machine. This rule of construction is transferred to a mathematical model, whereby the equations of motion are obtained. The only difference between the machine and its model is that instead of pulleys and bodies, we have reference frames that move solidarily with these objects. This model provides us with the accelerations in the non-inertial frames of the bodies, which we will use to obtain the equations of motion. This approach to the problem will be justified by the Lagrange method and exemplified by machines with six and eight bodies.
Diode Laser Sensor for Scramjet Inlet
2010-05-11
This work presents the development of an oxygen -based diode laser absorption sensor designed to be used in a supersonic combustion ramjet engine inlet...ADFA Abstract This work presents development of an oxygen -based diode laser absorption sensor designed to be used in a supersonic combustion ramjet... sensor needs to use oxygen as the absorbing species, as this is the only option for absorption measurements in inlet air. Oxygen absorption lines
Secure Autonomous Automated Scheduling (SAAS). Rev. 1.1
NASA Technical Reports Server (NTRS)
Walke, Jon G.; Dikeman, Larry; Sage, Stephen P.; Miller, Eric M.
2010-01-01
This report describes network-centric operations, where a virtual mission operations center autonomously receives sensor triggers, and schedules space and ground assets using Internet-based technologies and service-oriented architectures. For proof-of-concept purposes, sensor triggers are received from the United States Geological Survey (USGS) to determine targets for space-based sensors. The Surrey Satellite Technology Limited (SSTL) Disaster Monitoring Constellation satellite, the UK-DMC, is used as the space-based sensor. The UK-DMC's availability is determined via machine-to-machine communications using SSTL's mission planning system. Access to/from the UK-DMC for tasking and sensor data is via SSTL's and Universal Space Network's (USN) ground assets. The availability and scheduling of USN's assets can also be performed autonomously via machine-to-machine communications. All communication, both on the ground and between ground and space, uses open Internet standards
NASA Astrophysics Data System (ADS)
Sizov, Gennadi Y.
In this dissertation, a model-based multi-objective optimal design of permanent magnet ac machines, supplied by sine-wave current regulated drives, is developed and implemented. The design procedure uses an efficient electromagnetic finite element-based solver to accurately model nonlinear material properties and complex geometric shapes associated with magnetic circuit design. Application of an electromagnetic finite element-based solver allows for accurate computation of intricate performance parameters and characteristics. The first contribution of this dissertation is the development of a rapid computational method that allows accurate and efficient exploration of large multi-dimensional design spaces in search of optimum design(s). The computationally efficient finite element-based approach developed in this work provides a framework of tools that allow rapid analysis of synchronous electric machines operating under steady-state conditions. In the developed modeling approach, major steady-state performance parameters such as, winding flux linkages and voltages, average, cogging and ripple torques, stator core flux densities, core losses, efficiencies and saturated machine winding inductances, are calculated with minimum computational effort. In addition, the method includes means for rapid estimation of distributed stator forces and three-dimensional effects of stator and/or rotor skew on the performance of the machine. The second contribution of this dissertation is the development of the design synthesis and optimization method based on a differential evolution algorithm. The approach relies on the developed finite element-based modeling method for electromagnetic analysis and is able to tackle large-scale multi-objective design problems using modest computational resources. Overall, computational time savings of up to two orders of magnitude are achievable, when compared to current and prevalent state-of-the-art methods. These computational savings allow one to expand the optimization problem to achieve more complex and comprehensive design objectives. The method is used in the design process of several interior permanent magnet industrial motors. The presented case studies demonstrate that the developed finite element-based approach practically eliminates the need for using less accurate analytical and lumped parameter equivalent circuit models for electric machine design optimization. The design process and experimental validation of the case-study machines are detailed in the dissertation.
Innis, Jennifer; Berta, Whitney
2016-09-01
This paper uses the construct of absorptive capacity to understand how nurse managers can facilitate the adoption and use of evidence-based practice within health-care organisations. How health-care organisations adopt and implement innovations such as new evidence-based practices will depend on their absorptive, or learning, capacity. Absorptive capacity manifests as routines, which are the practices, procedures and customs that organisational members use to carry out work and to make work-related decisions. Using the construct of absorptive capacity as well as a recent literature review of how health-care organisations take on best practices, we illustrate how the uptake and use of new knowledge, such as evidence-based practices, can be facilitated through the use of routines. This paper highlights routines that nurse managers can use to foster environments where evidence-based practices can be readily identified, and strategies for facilitating their adoption and implementation. The construct of absorptive capacity and the use of routines can be used to examine the ways in which nurse managers can adopt, implement and evaluate the use of evidence-based practices. © 2016 John Wiley & Sons Ltd.
NASA Astrophysics Data System (ADS)
van Rheenen, Arthur D.; Taule, Petter; Thomassen, Jan Brede; Madsen, Eirik Blix
2018-04-01
We present Minimum-Resolvable Temperature Difference (MRTD) curves obtained by letting an ensemble of observers judge how many of the six four-bar patterns they can "see" in a set of images taken with different bar-to-background contrasts. The same images are analyzed using elemental signal analysis algorithms and machine-analysis based MRTD curves are obtained. We show that by adjusting the minimum required signal-to-noise ratio the machine-based MRTDs are very similar to the ones obtained with the help of the human observers.
Proceedings of the 1986 IEEE international conference on systems, man and cybernetics
DOE Office of Scientific and Technical Information (OSTI.GOV)
Not Available
1986-01-01
This book presents the papers given at a conference on man-machine systems. Topics considered at the conference included neural model-based cognitive theory and engineering, user interfaces, adaptive and learning systems, human interaction with robotics, decision making, the testing and evaluation of expert systems, software development, international conflict resolution, intelligent interfaces, automation in man-machine system design aiding, knowledge acquisition in expert systems, advanced architectures for artificial intelligence, pattern recognition, knowledge bases, and machine vision.
Man Machine Systems in Education.
ERIC Educational Resources Information Center
Sall, Malkit S.
This review of the research literature on the interaction between humans and computers discusses how man machine systems can be utilized effectively in the learning-teaching process, especially in secondary education. Beginning with a definition of man machine systems and comments on the poor quality of much of the computer-based learning material…
Optimization of processing parameters of UAV integral structural components based on yield response
NASA Astrophysics Data System (ADS)
Chen, Yunsheng
2018-05-01
In order to improve the overall strength of unmanned aerial vehicle (UAV), it is necessary to optimize the processing parameters of UAV structural components, which is affected by initial residual stress in the process of UAV structural components processing. Because machining errors are easy to occur, an optimization model for machining parameters of UAV integral structural components based on yield response is proposed. The finite element method is used to simulate the machining parameters of UAV integral structural components. The prediction model of workpiece surface machining error is established, and the influence of the path of walking knife on residual stress of UAV integral structure is studied, according to the stress of UAV integral component. The yield response of the time-varying stiffness is analyzed, and the yield response and the stress evolution mechanism of the UAV integral structure are analyzed. The simulation results show that this method is used to optimize the machining parameters of UAV integral structural components and improve the precision of UAV milling processing. The machining error is reduced, and the deformation prediction and error compensation of UAV integral structural parts are realized, thus improving the quality of machining.
Thutmose - Investigation of Machine Learning-Based Intrusion Detection Systems
2016-06-01
research is being done to incorporate the field of machine learning into intrusion detection. Machine learning is a branch of artificial intelligence (AI...adversarial drift." Proceedings of the 2013 ACM workshop on Artificial intelligence and security. ACM. (2013) Kantarcioglu, M., Xi, B., and Clifton, C. "A...34 Proceedings of the 4th ACM workshop on Security and artificial intelligence . ACM. (2011) Dua, S., and Du, X. Data Mining and Machine Learning in
Geometrical dependence of spin current absorption into a ferromagnetic nanodot
DOE Office of Scientific and Technical Information (OSTI.GOV)
Nomura, Tatsuya; Ohnishi, Kohei; Kimura, Takashi, E-mail: t-kimu@phys.kyushu-u.ac.jp
We have investigated the absorption property of the diffusive pure spin current due to a ferromagnetic nanodot in a laterally configured ferromagnetic/nonmagnetic hybrid nanostructure. The spin absorption in a nano-pillar-based lateral-spin-valve structure was confirmed to increase with increasing the lateral dimension of the ferromagnetic dot. However, the absorption efficiency was smaller than that in a conventional lateral spin valve based on nanowire junctions because the large effective cross section of the two dimensional nonmagnetic film reduces the spin absorption selectivity. We also found that the absorption efficiency of the spin current is significantly enhanced by using a thick ferromagnetic nanodot.more » This can be understood by taking into account the spin absorption through the side surface of the ferromagnetic dot quantitatively.« less
Industrial ion source technology. [for ion beam etching, surface texturing, and deposition
NASA Technical Reports Server (NTRS)
Kaufman, H. R.
1977-01-01
Plasma probe surveys were conducted in a 30-cm source to verify that the uniformity in the ion beam is the result of a corresponding uniformity in the discharge-chamber plasma. A 15 cm permanent magnet multipole ion source was designed, fabricated, and demonstrated. Procedures were investigated for texturing a variety of seed and surface materials for controlling secondary electron emission, increasing electron absorption of light, and improved attachment of biological tissue for medical implants using argon and tetrafluoromethane as the working gases. The cross section for argon-argon elastic collisions in the ion-beam energy range was calculated from interaction potentials and permits calculation of beam interaction effects that can determine system pumping requirements. The data also indicate that different optimizations of ion-beam machines will be advantageous for long and short runs, with 1 mA-hr/cm being the rough dividing line for run length. The capacity to simultaneously optimize components in an ion-beam machine for a single application, a capacity that is not evident in competitive approaches such as diode sputtering is emphasized.
Hussain, Lal
2018-06-01
Epilepsy is a neurological disorder produced due to abnormal excitability of neurons in the brain. The research reveals that brain activity is monitored through electroencephalogram (EEG) of patients suffered from seizure to detect the epileptic seizure. The performance of EEG detection based epilepsy require feature extracting strategies. In this research, we have extracted varying features extracting strategies based on time and frequency domain characteristics, nonlinear, wavelet based entropy and few statistical features. A deeper study was undertaken using novel machine learning classifiers by considering multiple factors. The support vector machine kernels are evaluated based on multiclass kernel and box constraint level. Likewise, for K-nearest neighbors (KNN), we computed the different distance metrics, Neighbor weights and Neighbors. Similarly, the decision trees we tuned the paramours based on maximum splits and split criteria and ensemble classifiers are evaluated based on different ensemble methods and learning rate. For training/testing tenfold Cross validation was employed and performance was evaluated in form of TPR, NPR, PPV, accuracy and AUC. In this research, a deeper analysis approach was performed using diverse features extracting strategies using robust machine learning classifiers with more advanced optimal options. Support Vector Machine linear kernel and KNN with City block distance metric give the overall highest accuracy of 99.5% which was higher than using the default parameters for these classifiers. Moreover, highest separation (AUC = 0.9991, 0.9990) were obtained at different kernel scales using SVM. Additionally, the K-nearest neighbors with inverse squared distance weight give higher performance at different Neighbors. Moreover, to distinguish the postictal heart rate oscillations from epileptic ictal subjects, and highest performance of 100% was obtained using different machine learning classifiers.
High-throughput state-machine replication using software transactional memory.
Zhao, Wenbing; Yang, William; Zhang, Honglei; Yang, Jack; Luo, Xiong; Zhu, Yueqin; Yang, Mary; Luo, Chaomin
2016-11-01
State-machine replication is a common way of constructing general purpose fault tolerance systems. To ensure replica consistency, requests must be executed sequentially according to some total order at all non-faulty replicas. Unfortunately, this could severely limit the system throughput. This issue has been partially addressed by identifying non-conflicting requests based on application semantics and executing these requests concurrently. However, identifying and tracking non-conflicting requests require intimate knowledge of application design and implementation, and a custom fault tolerance solution developed for one application cannot be easily adopted by other applications. Software transactional memory offers a new way of constructing concurrent programs. In this article, we present the mechanisms needed to retrofit existing concurrency control algorithms designed for software transactional memory for state-machine replication. The main benefit for using software transactional memory in state-machine replication is that general purpose concurrency control mechanisms can be designed without deep knowledge of application semantics. As such, new fault tolerance systems based on state-machine replications with excellent throughput can be easily designed and maintained. In this article, we introduce three different concurrency control mechanisms for state-machine replication using software transactional memory, namely, ordered strong strict two-phase locking, conventional timestamp-based multiversion concurrency control, and speculative timestamp-based multiversion concurrency control. Our experiments show that speculative timestamp-based multiversion concurrency control mechanism has the best performance in all types of workload, the conventional timestamp-based multiversion concurrency control offers the worst performance due to high abort rate in the presence of even moderate contention between transactions. The ordered strong strict two-phase locking mechanism offers the simplest solution with excellent performance in low contention workload, and fairly good performance in high contention workload.
High-throughput state-machine replication using software transactional memory
Yang, William; Zhang, Honglei; Yang, Jack; Luo, Xiong; Zhu, Yueqin; Yang, Mary; Luo, Chaomin
2017-01-01
State-machine replication is a common way of constructing general purpose fault tolerance systems. To ensure replica consistency, requests must be executed sequentially according to some total order at all non-faulty replicas. Unfortunately, this could severely limit the system throughput. This issue has been partially addressed by identifying non-conflicting requests based on application semantics and executing these requests concurrently. However, identifying and tracking non-conflicting requests require intimate knowledge of application design and implementation, and a custom fault tolerance solution developed for one application cannot be easily adopted by other applications. Software transactional memory offers a new way of constructing concurrent programs. In this article, we present the mechanisms needed to retrofit existing concurrency control algorithms designed for software transactional memory for state-machine replication. The main benefit for using software transactional memory in state-machine replication is that general purpose concurrency control mechanisms can be designed without deep knowledge of application semantics. As such, new fault tolerance systems based on state-machine replications with excellent throughput can be easily designed and maintained. In this article, we introduce three different concurrency control mechanisms for state-machine replication using software transactional memory, namely, ordered strong strict two-phase locking, conventional timestamp-based multiversion concurrency control, and speculative timestamp-based multiversion concurrency control. Our experiments show that speculative timestamp-based multiversion concurrency control mechanism has the best performance in all types of workload, the conventional timestamp-based multiversion concurrency control offers the worst performance due to high abort rate in the presence of even moderate contention between transactions. The ordered strong strict two-phase locking mechanism offers the simplest solution with excellent performance in low contention workload, and fairly good performance in high contention workload. PMID:29075049
Pai, Yun Suen; Yap, Hwa Jen; Md Dawal, Siti Zawiah; Ramesh, S.; Phoon, Sin Ye
2016-01-01
This study presents a modular-based implementation of augmented reality to provide an immersive experience in learning or teaching the planning phase, control system, and machining parameters of a fully automated work cell. The architecture of the system consists of three code modules that can operate independently or combined to create a complete system that is able to guide engineers from the layout planning phase to the prototyping of the final product. The layout planning module determines the best possible arrangement in a layout for the placement of various machines, in this case a conveyor belt for transportation, a robot arm for pick-and-place operations, and a computer numerical control milling machine to generate the final prototype. The robotic arm module simulates the pick-and-place operation offline from the conveyor belt to a computer numerical control (CNC) machine utilising collision detection and inverse kinematics. Finally, the CNC module performs virtual machining based on the Uniform Space Decomposition method and axis aligned bounding box collision detection. The conducted case study revealed that given the situation, a semi-circle shaped arrangement is desirable, whereas the pick-and-place system and the final generated G-code produced the highest deviation of 3.83 mm and 5.8 mm respectively. PMID:27271840
Bidding-based autonomous process planning and scheduling
NASA Astrophysics Data System (ADS)
Gu, Peihua; Balasubramanian, Sivaram; Norrie, Douglas H.
1995-08-01
Improving productivity through computer integrated manufacturing systems (CIMS) and concurrent engineering requires that the islands of automation in an enterprise be completely integrated. The first step in this direction is to integrate design, process planning, and scheduling. This can be achieved through a bidding-based process planning approach. The product is represented in a STEP model with detailed design and administrative information including design specifications, batch size, and due dates. Upon arrival at the manufacturing facility, the product registered in the shop floor manager which is essentially a coordinating agent. The shop floor manager broadcasts the product's requirements to the machines. The shop contains autonomous machines that have knowledge about their functionality, capabilities, tooling, and schedule. Each machine has its own process planner and responds to the product's request in a different way that is consistent with its capabilities and capacities. When more than one machine offers certain process(es) for the same requirements, they enter into negotiation. Based on processing time, due date, and cost, one of the machines wins the contract. The successful machine updates its schedule and advises the product to request raw material for processing. The concept was implemented using a multi-agent system with the task decomposition and planning achieved through contract nets. The examples are included to illustrate the approach.
Lee, Haerin; Jung, Moonki; Lee, Ki-Kwang; Lee, Sang Hun
2017-02-06
In this paper, we propose a three-dimensional design and evaluation framework and process based on a probabilistic-based motion synthesis algorithm and biomechanical analysis system for the design of the Smith machine and squat training programs. Moreover, we implemented a prototype system to validate the proposed framework. The framework consists of an integrated human-machine-environment model as well as a squat motion synthesis system and biomechanical analysis system. In the design and evaluation process, we created an integrated model in which interactions between a human body and machine or the ground are modeled as joints with constraints at contact points. Next, we generated Smith squat motion using the motion synthesis program based on a Gaussian process regression algorithm with a set of given values for independent variables. Then, using the biomechanical analysis system, we simulated joint moments and muscle activities from the input of the integrated model and squat motion. We validated the model and algorithm through physical experiments measuring the electromyography (EMG) signals, ground forces, and squat motions as well as through a biomechanical simulation of muscle forces. The proposed approach enables the incorporation of biomechanics in the design process and reduces the need for physical experiments and prototypes in the development of training programs and new Smith machines.
Pai, Yun Suen; Yap, Hwa Jen; Md Dawal, Siti Zawiah; Ramesh, S; Phoon, Sin Ye
2016-06-07
This study presents a modular-based implementation of augmented reality to provide an immersive experience in learning or teaching the planning phase, control system, and machining parameters of a fully automated work cell. The architecture of the system consists of three code modules that can operate independently or combined to create a complete system that is able to guide engineers from the layout planning phase to the prototyping of the final product. The layout planning module determines the best possible arrangement in a layout for the placement of various machines, in this case a conveyor belt for transportation, a robot arm for pick-and-place operations, and a computer numerical control milling machine to generate the final prototype. The robotic arm module simulates the pick-and-place operation offline from the conveyor belt to a computer numerical control (CNC) machine utilising collision detection and inverse kinematics. Finally, the CNC module performs virtual machining based on the Uniform Space Decomposition method and axis aligned bounding box collision detection. The conducted case study revealed that given the situation, a semi-circle shaped arrangement is desirable, whereas the pick-and-place system and the final generated G-code produced the highest deviation of 3.83 mm and 5.8 mm respectively.
NASA Astrophysics Data System (ADS)
Pai, Yun Suen; Yap, Hwa Jen; Md Dawal, Siti Zawiah; Ramesh, S.; Phoon, Sin Ye
2016-06-01
This study presents a modular-based implementation of augmented reality to provide an immersive experience in learning or teaching the planning phase, control system, and machining parameters of a fully automated work cell. The architecture of the system consists of three code modules that can operate independently or combined to create a complete system that is able to guide engineers from the layout planning phase to the prototyping of the final product. The layout planning module determines the best possible arrangement in a layout for the placement of various machines, in this case a conveyor belt for transportation, a robot arm for pick-and-place operations, and a computer numerical control milling machine to generate the final prototype. The robotic arm module simulates the pick-and-place operation offline from the conveyor belt to a computer numerical control (CNC) machine utilising collision detection and inverse kinematics. Finally, the CNC module performs virtual machining based on the Uniform Space Decomposition method and axis aligned bounding box collision detection. The conducted case study revealed that given the situation, a semi-circle shaped arrangement is desirable, whereas the pick-and-place system and the final generated G-code produced the highest deviation of 3.83 mm and 5.8 mm respectively.
Virtual screening by a new Clustering-based Weighted Similarity Extreme Learning Machine approach
Kudisthalert, Wasu
2018-01-01
Machine learning techniques are becoming popular in virtual screening tasks. One of the powerful machine learning algorithms is Extreme Learning Machine (ELM) which has been applied to many applications and has recently been applied to virtual screening. We propose the Weighted Similarity ELM (WS-ELM) which is based on a single layer feed-forward neural network in a conjunction of 16 different similarity coefficients as activation function in the hidden layer. It is known that the performance of conventional ELM is not robust due to random weight selection in the hidden layer. Thus, we propose a Clustering-based WS-ELM (CWS-ELM) that deterministically assigns weights by utilising clustering algorithms i.e. k-means clustering and support vector clustering. The experiments were conducted on one of the most challenging datasets–Maximum Unbiased Validation Dataset–which contains 17 activity classes carefully selected from PubChem. The proposed algorithms were then compared with other machine learning techniques such as support vector machine, random forest, and similarity searching. The results show that CWS-ELM in conjunction with support vector clustering yields the best performance when utilised together with Sokal/Sneath(1) coefficient. Furthermore, ECFP_6 fingerprint presents the best results in our framework compared to the other types of fingerprints, namely ECFP_4, FCFP_4, and FCFP_6. PMID:29652912
Machine vision based quality inspection of flat glass products
NASA Astrophysics Data System (ADS)
Zauner, G.; Schagerl, M.
2014-03-01
This application paper presents a machine vision solution for the quality inspection of flat glass products. A contact image sensor (CIS) is used to generate digital images of the glass surfaces. The presented machine vision based quality inspection at the end of the production line aims to classify five different glass defect types. The defect images are usually characterized by very little `image structure', i.e. homogeneous regions without distinct image texture. Additionally, these defect images usually consist of only a few pixels. At the same time the appearance of certain defect classes can be very diverse (e.g. water drops). We used simple state-of-the-art image features like histogram-based features (std. deviation, curtosis, skewness), geometric features (form factor/elongation, eccentricity, Hu-moments) and texture features (grey level run length matrix, co-occurrence matrix) to extract defect information. The main contribution of this work now lies in the systematic evaluation of various machine learning algorithms to identify appropriate classification approaches for this specific class of images. In this way, the following machine learning algorithms were compared: decision tree (J48), random forest, JRip rules, naive Bayes, Support Vector Machine (multi class), neural network (multilayer perceptron) and k-Nearest Neighbour. We used a representative image database of 2300 defect images and applied cross validation for evaluation purposes.
Numerical simulation of polishing U-tube based on solid-liquid two-phase
NASA Astrophysics Data System (ADS)
Li, Jun-ye; Meng, Wen-qing; Wu, Gui-ling; Hu, Jing-lei; Wang, Bao-zuo
2018-03-01
As the advanced technology to solve the ultra-precision machining of small hole structure parts and complex cavity parts, the abrasive grain flow processing technology has the characteristics of high efficiency, high quality and low cost. So this technology in many areas of precision machining has an important role. Based on the theory of solid-liquid two-phase flow coupling, a solid-liquid two-phase MIXTURE model is used to simulate the abrasive flow polishing process on the inner surface of U-tube, and the temperature, turbulent viscosity and turbulent dissipation rate in the process of abrasive flow machining of U-tube were compared and analyzed under different inlet pressure. In this paper, the influence of different inlet pressure on the surface quality of the workpiece during abrasive flow machining is studied and discussed, which provides a theoretical basis for the research of abrasive flow machining process.
Wang, Zhi-Long; Zhou, Zhi-Guo; Chen, Ying; Li, Xiao-Ting; Sun, Ying-Shi
The aim of this study was to diagnose lymph node metastasis of esophageal cancer by support vector machines model based on computed tomography. A total of 131 esophageal cancer patients with preoperative chemotherapy and radical surgery were included. Various indicators (tumor thickness, tumor length, tumor CT value, total number of lymph nodes, and long axis and short axis sizes of largest lymph node) on CT images before and after neoadjuvant chemotherapy were recorded. A support vector machines model based on these CT indicators was built to predict lymph node metastasis. Support vector machines model diagnosed lymph node metastasis better than preoperative short axis size of largest lymph node on CT. The area under the receiver operating characteristic curves were 0.887 and 0.705, respectively. The support vector machine model of CT images can help diagnose lymph node metastasis in esophageal cancer with preoperative chemotherapy.
Vibration Sensor Monitoring of Nickel-Titanium Alloy Turning for Machinability Evaluation.
Segreto, Tiziana; Caggiano, Alessandra; Karam, Sara; Teti, Roberto
2017-12-12
Nickel-Titanium (Ni-Ti) alloys are very difficult-to-machine materials causing notable manufacturing problems due to their unique mechanical properties, including superelasticity, high ductility, and severe strain-hardening. In this framework, the aim of this paper is to assess the machinability of Ni-Ti alloys with reference to turning processes in order to realize a reliable and robust in-process identification of machinability conditions. An on-line sensor monitoring procedure based on the acquisition of vibration signals was implemented during the experimental turning tests. The detected vibration sensorial data were processed through an advanced signal processing method in time-frequency domain based on wavelet packet transform (WPT). The extracted sensorial features were used to construct WPT pattern feature vectors to send as input to suitably configured neural networks (NNs) for cognitive pattern recognition in order to evaluate the correlation between input sensorial information and output machinability conditions.
Vibration Sensor Monitoring of Nickel-Titanium Alloy Turning for Machinability Evaluation
Segreto, Tiziana; Karam, Sara; Teti, Roberto
2017-01-01
Nickel-Titanium (Ni-Ti) alloys are very difficult-to-machine materials causing notable manufacturing problems due to their unique mechanical properties, including superelasticity, high ductility, and severe strain-hardening. In this framework, the aim of this paper is to assess the machinability of Ni-Ti alloys with reference to turning processes in order to realize a reliable and robust in-process identification of machinability conditions. An on-line sensor monitoring procedure based on the acquisition of vibration signals was implemented during the experimental turning tests. The detected vibration sensorial data were processed through an advanced signal processing method in time-frequency domain based on wavelet packet transform (WPT). The extracted sensorial features were used to construct WPT pattern feature vectors to send as input to suitably configured neural networks (NNs) for cognitive pattern recognition in order to evaluate the correlation between input sensorial information and output machinability conditions. PMID:29231864
Health Informatics via Machine Learning for the Clinical Management of Patients.
Clifton, D A; Niehaus, K E; Charlton, P; Colopy, G W
2015-08-13
To review how health informatics systems based on machine learning methods have impacted the clinical management of patients, by affecting clinical practice. We reviewed literature from 2010-2015 from databases such as Pubmed, IEEE xplore, and INSPEC, in which methods based on machine learning are likely to be reported. We bring together a broad body of literature, aiming to identify those leading examples of health informatics that have advanced the methodology of machine learning. While individual methods may have further examples that might be added, we have chosen some of the most representative, informative exemplars in each case. Our survey highlights that, while much research is taking place in this high-profile field, examples of those that affect the clinical management of patients are seldom found. We show that substantial progress is being made in terms of methodology, often by data scientists working in close collaboration with clinical groups. Health informatics systems based on machine learning are in their infancy and the translation of such systems into clinical management has yet to be performed at scale.
Zhang, Sa; Li, Zhou; Xin, Xue-Gang
2017-12-20
To achieve differential diagnosis of normal and malignant gastric tissues based on discrepancies in their dielectric properties using support vector machine. The dielectric properties of normal and malignant gastric tissues at the frequency ranging from 42.58 to 500 MHz were measured by coaxial probe method, and the Cole?Cole model was used to fit the measured data. Receiver?operating characteristic (ROC) curve analysis was used to evaluate the discrimination capability with respect to permittivity, conductivity, and Cole?Cole fitting parameters. Support vector machine was used for discriminating normal and malignant gastric tissues, and the discrimination accuracy was calculated using k?fold cross? The area under the ROC curve was above 0.8 for permittivity at the 5 frequencies at the lower end of the measured frequency range. The combination of the support vector machine with the permittivity at all these 5 frequencies combined achieved the highest discrimination accuracy of 84.38% with a MATLAB runtime of 3.40 s. The support vector machine?assisted diagnosis is feasible for human malignant gastric tissues based on the dielectric properties.
Aggregation of Electric Current Consumption Features to Extract Maintenance KPIs
NASA Astrophysics Data System (ADS)
Simon, Victor; Johansson, Carl-Anders; Galar, Diego
2017-09-01
All electric powered machines offer the possibility of extracting information and calculating Key Performance Indicators (KPIs) from the electric current signal. Depending on the time window, sampling frequency and type of analysis, different indicators from the micro to macro level can be calculated for such aspects as maintenance, production, energy consumption etc. On the micro-level, the indicators are generally used for condition monitoring and diagnostics and are normally based on a short time window and a high sampling frequency. The macro indicators are normally based on a longer time window with a slower sampling frequency and are used as indicators for overall performance, cost or consumption. The indicators can be calculated directly from the current signal but can also be based on a combination of information from the current signal and operational data like rpm, position etc. One or several of those indicators can be used for prediction and prognostics of a machine's future behavior. This paper uses this technique to calculate indicators for maintenance and energy optimization in electric powered machines and fleets of machines, especially machine tools.
Kocer, Hasan; Butun, Serkan; Palacios, Edgar; Liu, Zizhuo; Tongay, Sefaattin; Fu, Deyi; Wang, Kevin; Wu, Junqiao; Aydin, Koray
2015-01-01
Plasmonic and metamaterial based nano/micro-structured materials enable spectrally selective resonant absorption, where the resonant bandwidth and absorption intensity can be engineered by controlling the size and geometry of nanostructures. Here, we demonstrate a simple, lithography-free approach for obtaining a resonant and dynamically tunable broadband absorber based on vanadium dioxide (VO2) phase transition. Using planar layered thin film structures, where top layer is chosen to be an ultrathin (20 nm) VO2 film, we demonstrate broadband IR light absorption tuning (from ~90% to ~30% in measured absorption) over the entire mid-wavelength infrared spectrum. Our numerical and experimental results indicate that the bandwidth of the absorption bands can be controlled by changing the dielectric spacer layer thickness. Broadband tunable absorbers can find applications in absorption filters, thermal emitters, thermophotovoltaics and sensing. PMID:26294085
Machine listening intelligence
NASA Astrophysics Data System (ADS)
Cella, C. E.
2017-05-01
This manifesto paper will introduce machine listening intelligence, an integrated research framework for acoustic and musical signals modelling, based on signal processing, deep learning and computational musicology.
Alcaide-Leon, P; Dufort, P; Geraldo, A F; Alshafai, L; Maralani, P J; Spears, J; Bharatha, A
2017-06-01
Accurate preoperative differentiation of primary central nervous system lymphoma and enhancing glioma is essential to avoid unnecessary neurosurgical resection in patients with primary central nervous system lymphoma. The purpose of the study was to evaluate the diagnostic performance of a machine-learning algorithm by using texture analysis of contrast-enhanced T1-weighted images for differentiation of primary central nervous system lymphoma and enhancing glioma. Seventy-one adult patients with enhancing gliomas and 35 adult patients with primary central nervous system lymphomas were included. The tumors were manually contoured on contrast-enhanced T1WI, and the resulting volumes of interest were mined for textural features and subjected to a support vector machine-based machine-learning protocol. Three readers classified the tumors independently on contrast-enhanced T1WI. Areas under the receiver operating characteristic curves were estimated for each reader and for the support vector machine classifier. A noninferiority test for diagnostic accuracy based on paired areas under the receiver operating characteristic curve was performed with a noninferiority margin of 0.15. The mean areas under the receiver operating characteristic curve were 0.877 (95% CI, 0.798-0.955) for the support vector machine classifier; 0.878 (95% CI, 0.807-0.949) for reader 1; 0.899 (95% CI, 0.833-0.966) for reader 2; and 0.845 (95% CI, 0.757-0.933) for reader 3. The mean area under the receiver operating characteristic curve of the support vector machine classifier was significantly noninferior to the mean area under the curve of reader 1 ( P = .021), reader 2 ( P = .035), and reader 3 ( P = .007). Support vector machine classification based on textural features of contrast-enhanced T1WI is noninferior to expert human evaluation in the differentiation of primary central nervous system lymphoma and enhancing glioma. © 2017 by American Journal of Neuroradiology.
Experimental investigation of the tip based micro/nano machining
NASA Astrophysics Data System (ADS)
Guo, Z.; Tian, Y.; Liu, X.; Wang, F.; Zhou, C.; Zhang, D.
2017-12-01
Based on the self-developed three dimensional micro/nano machining system, the effects of machining parameters and sample material on micro/nano machining are investigated. The micro/nano machining system is mainly composed of the probe system and micro/nano positioning stage. The former is applied to control the normal load and the latter is utilized to realize high precision motion in the xy plane. A sample examination method is firstly introduced to estimate whether the sample is placed horizontally. The machining parameters include scratching direction, speed, cycles, normal load and feed. According to the experimental results, the scratching depth is significantly affected by the normal load in all four defined scratching directions but is rarely influenced by the scratching speed. The increase of scratching cycle number can increase the scratching depth as well as smooth the groove wall. In addition, the scratching tests of silicon and copper attest that the harder material is easier to be removed. In the scratching with different feed amount, the machining results indicate that the machined depth increases as the feed reduces. Further, a cubic polynomial is used to fit the experimental results to predict the scratching depth. With the selected machining parameters of scratching direction d3/d4, scratching speed 5 μm/s and feed 0.06 μm, some more micro structures including stair, sinusoidal groove, Chinese character '田', 'TJU' and Chinese panda have been fabricated on the silicon substrate.
Fault detection in rotating machines with beamforming: Spatial visualization of diagnosis features
NASA Astrophysics Data System (ADS)
Cardenas Cabada, E.; Leclere, Q.; Antoni, J.; Hamzaoui, N.
2017-12-01
Rotating machines diagnosis is conventionally related to vibration analysis. Sensors are usually placed on the machine to gather information about its components. The recorded signals are then processed through a fault detection algorithm allowing the identification of the failing part. This paper proposes an acoustic-based diagnosis method. A microphone array is used to record the acoustic field radiated by the machine. The main advantage over vibration-based diagnosis is that the contact between the sensors and the machine is no longer required. Moreover, the application of acoustic imaging makes possible the identification of the sources of acoustic radiation on the machine surface. The display of information is then spatially continuous while the accelerometers only give it discrete. Beamforming provides the time-varying signals radiated by the machine as a function of space. Any fault detection tool can be applied to the beamforming output. Spectral kurtosis, which highlights the impulsiveness of a signal as function of frequency, is used in this study. The combination of spectral kurtosis with acoustic imaging makes possible the mapping of the impulsiveness as a function of space and frequency. The efficiency of this approach lays on the source separation in the spatial and frequency domains. These mappings make possible the localization of such impulsive sources. The faulty components of the machine have an impulsive behavior and thus will be highlighted on the mappings. The study presents experimental validations of the method on rotating machines.
A Double-Sided Linear Primary Permanent Magnet Vernier Machine
2015-01-01
The purpose of this paper is to present a new double-sided linear primary permanent magnet (PM) vernier (DSLPPMV) machine, which can offer high thrust force, low detent force, and improved power factor. Both PMs and windings of the proposed machine are on the short translator, while the long stator is designed as a double-sided simple iron core with salient teeth so that it is very robust to transmit high thrust force. The key of this new machine is the introduction of double stator and the elimination of translator yoke, so that the inductance and the volume of the machine can be reduced. Hence, the proposed machine offers improved power factor and thrust force density. The electromagnetic performances of the proposed machine are analyzed including flux, no-load EMF, thrust force density, and inductance. Based on using the finite element analysis, the characteristics and performances of the proposed machine are assessed. PMID:25874250
A double-sided linear primary permanent magnet vernier machine.
Du, Yi; Zou, Chunhua; Liu, Xianxing
2015-01-01
The purpose of this paper is to present a new double-sided linear primary permanent magnet (PM) vernier (DSLPPMV) machine, which can offer high thrust force, low detent force, and improved power factor. Both PMs and windings of the proposed machine are on the short translator, while the long stator is designed as a double-sided simple iron core with salient teeth so that it is very robust to transmit high thrust force. The key of this new machine is the introduction of double stator and the elimination of translator yoke, so that the inductance and the volume of the machine can be reduced. Hence, the proposed machine offers improved power factor and thrust force density. The electromagnetic performances of the proposed machine are analyzed including flux, no-load EMF, thrust force density, and inductance. Based on using the finite element analysis, the characteristics and performances of the proposed machine are assessed.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Robinson, J.C.; Young, J.C.; Rickert, W.S.
Twenty-two volunteers who smoked more than 20 cigarettes with ''high'' nicotine yields (0.8 to 1.2 mg) per day participated in an 8-week study designed to test the hypothesis that smoking cigarettes with a constant level of nicotine but reduced deliveries of tar, carbon monoxide, and hydrogen cyanide leads to a decrease in smoke absorption. All subjects smoked their usual high-nicotine brand for the first 3 weeks (P1), and the absorption of smoke constituents was determined from levels of thiocyanate and cotinine in saliva and serum, levels of carbon monoxide in expired air, and levels of carboxyhemoglobin in the blood. Duringmore » the final 5 weeks (P2), the treatment group (16 subjects) switched to the ''light'' version of their usual brands (similar yields of nicotine but with reduced yields of tar, carbon monoxide, and hydrogen cyanide); the control group (6 subjects) smoked their usual brands for the duration of the study. Average levels of cotinine for the subjects who switched during P2 were not significantly different from those of the control group as was expected. Slight reductions were noted in average expired-air carbon monoxide levels, blood carboxyhemoglobin, and saliva thiocyanate, but these reductions were smaller than anticipated based on brand characteristics. The results suggest that the ratio of smoke constituents is different when individuals, rather than machines, smoke cigarettes. Yields determined under subject-defined conditions are necessary in order to properly evaluate the role of nicotine in the design of ''less-hazardous'' cigarettes.« less
NASA Astrophysics Data System (ADS)
Karolina, R.; Muhammad, W.; Saragih, M. D. S. M.; Mustaqa, T.
2018-02-01
Self Compacting Concrete is a concrete variant that has a high degree of workability and also has great initial strength, but low water cement factor. It is also self-flowable that can be molded on formwork with a very little or no compacted use of compactors. This concrete, using a variety of aggregate sizes, aggregate portions and superplasticizer admixture to achieve a special viscosity that allows it to flow on its own without the aid of a compactor. Lightweight concrete brick is a type of brick made from cement, sand, water, and developers. Lightweight concrete bricks are divided into 2 based on the developed materials used are AAC (Autoclave Aerated Concrete) using aluminum paste and CLC (Cellular Lightweight Concrete) that use Foaming Agent from BASF as a developer material. In this experiment, the lightweight bricks that will be made are CLC type which uses Foaming Agent as the developer material by mixing the Ash Stone produced by Stone Crusher machine which has the density of 2666 kg / m3 as Partial Pair Substitution. In this study the variation of Ash Stone used is 10%, 15%, and 20% of the planned amount of sand. After doing the tasting the result is obtained for 10% variation. Compressive Strength and Absorption Increase will decrease by 25.07% and 39.005% and Variation of 15% compressive strength will decrease by 65,8% and decrease of absorbtion equal to 17,441% and variation of 20% compressive strength will decreased by 67,4 and absorption increase equal to 17,956%.
Wideband absorption in one dimensional photonic crystal with graphene-based hyperbolic metamaterials
NASA Astrophysics Data System (ADS)
Kang, Yongqiang; Liu, Hongmei
2018-02-01
A broadband absorber which was proposed by one dimensional photonic crystal (1DPC) containing graphene-based hyperbolic metamaterials (GHMM) is theoretically investigated. For TM mode, it was demonstrated to absorb roughly 90% of all available electromagnetic waves at a 14 THz absorption bandwidth at normal incidence. The absorption bandwidth was affected by Fermi energy and thickness of dielectric layer. When the incident angle was increased, the absorption value decreased, and the absorption band had a gradual blue shift. These findings have potential applications for designing broadband optoelectronic devices at mid-infrared and THz frequency range.
ERIC Educational Resources Information Center
Marulcu, Ismail
2010-01-01
This mixed method study examined the impact of a LEGO-based, engineering-oriented curriculum compared to an inquiry-based curriculum on fifth graders' content learning of simple machines. This study takes a social constructivist theoretical stance that science learning involves learning scientific concepts and their relations to each other. From…
Machine learning molecular dynamics for the simulation of infrared spectra.
Gastegger, Michael; Behler, Jörg; Marquetand, Philipp
2017-10-01
Machine learning has emerged as an invaluable tool in many research areas. In the present work, we harness this power to predict highly accurate molecular infrared spectra with unprecedented computational efficiency. To account for vibrational anharmonic and dynamical effects - typically neglected by conventional quantum chemistry approaches - we base our machine learning strategy on ab initio molecular dynamics simulations. While these simulations are usually extremely time consuming even for small molecules, we overcome these limitations by leveraging the power of a variety of machine learning techniques, not only accelerating simulations by several orders of magnitude, but also greatly extending the size of systems that can be treated. To this end, we develop a molecular dipole moment model based on environment dependent neural network charges and combine it with the neural network potential approach of Behler and Parrinello. Contrary to the prevalent big data philosophy, we are able to obtain very accurate machine learning models for the prediction of infrared spectra based on only a few hundreds of electronic structure reference points. This is made possible through the use of molecular forces during neural network potential training and the introduction of a fully automated sampling scheme. We demonstrate the power of our machine learning approach by applying it to model the infrared spectra of a methanol molecule, n -alkanes containing up to 200 atoms and the protonated alanine tripeptide, which at the same time represents the first application of machine learning techniques to simulate the dynamics of a peptide. In all of these case studies we find an excellent agreement between the infrared spectra predicted via machine learning models and the respective theoretical and experimental spectra.
Virtual Mission Operations of Remote Sensors With Rapid Access To and From Space
NASA Technical Reports Server (NTRS)
Ivancic, William D.; Stewart, Dave; Walke, Jon; Dikeman, Larry; Sage, Steven; Miller, Eric; Northam, James; Jackson, Chris; Taylor, John; Lynch, Scott;
2010-01-01
This paper describes network-centric operations, where a virtual mission operations center autonomously receives sensor triggers, and schedules space and ground assets using Internet-based technologies and service-oriented architectures. For proof-of-concept purposes, sensor triggers are received from the United States Geological Survey (USGS) to determine targets for space-based sensors. The Surrey Satellite Technology Limited (SSTL) Disaster Monitoring Constellation satellite, the United Kingdom Disaster Monitoring Constellation (UK-DMC), is used as the space-based sensor. The UK-DMC s availability is determined via machine-to-machine communications using SSTL s mission planning system. Access to/from the UK-DMC for tasking and sensor data is via SSTL s and Universal Space Network s (USN) ground assets. The availability and scheduling of USN s assets can also be performed autonomously via machine-to-machine communications. All communication, both on the ground and between ground and space, uses open Internet standards.
Nanocomposites for Machining Tools
Loginov, Pavel; Mishnaevsky, Leon; Levashov, Evgeny
2017-01-01
Machining tools are used in many areas of production. To a considerable extent, the performance characteristics of the tools determine the quality and cost of obtained products. The main materials used for producing machining tools are steel, cemented carbides, ceramics and superhard materials. A promising way to improve the performance characteristics of these materials is to design new nanocomposites based on them. The application of micromechanical modeling during the elaboration of composite materials for machining tools can reduce the financial and time costs for development of new tools, with enhanced performance. This article reviews the main groups of nanocomposites for machining tools and their performance. PMID:29027926
Multicutter machining of compound parametric surfaces
NASA Astrophysics Data System (ADS)
Hatna, Abdelmadjid; Grieve, R. J.; Broomhead, P.
2000-10-01
Parametric free forms are used in industries as disparate as footwear, toys, sporting goods, ceramics, digital content creation, and conceptual design. Optimizing tool path patterns and minimizing the total machining time is a primordial issue in numerically controlled (NC) machining of free form surfaces. We demonstrate in the present work that multi-cutter machining can achieve as much as 60% reduction in total machining time for compound sculptured surfaces. The given approach is based upon the pre-processing as opposed to the usual post-processing of surfaces for the detection and removal of interference followed by precise tracking of unmachined areas.
NASA Astrophysics Data System (ADS)
Liang, Jiran; Li, Peng; Zhou, Liwei; Guo, Jinbang; Zhao, Yirui
2018-01-01
We proposed a metamaterial absorber which is aimed to achieve a multiple broadband absorption and tunable absorption peak in the near-infrared region. The absorber is based on VO2 semi-shell coated on the top of silica nano-particle array supported on the gold-reflective layer. Measured results show that the absorber has the multiple broadband with the absorption magnitudes more than 95% in the near infrared region. The absorption peaks can be tuned through the VO2 phase transition from metallic phase to insulator phase in the short wavelength (before λ = 1500 nm), when VO2 is at the metallic state, an absorption band appears in the long wavelength (after λ = 1500 nm). The simulation results closely match those of measured. The absorption intensity becomes stronger and absorption peaks have red shift with the increase of thickness of VO2 semi-shell. Thus, this designed tunable absorption intensity and position absorber based on VO2 can be a good choice for enhancing the performance of multiple band, this would be beneficial to the field of photo detectors, sensor and solar cell.
Adding Test Generation to the Teaching Machine
ERIC Educational Resources Information Center
Bruce-Lockhart, Michael; Norvell, Theodore; Crescenzi, Pierluigi
2009-01-01
We propose an extension of the Teaching Machine project, called Quiz Generator, that allows instructors to produce assessment quizzes in the field of algorithm and data structures quite easily. This extension makes use of visualization techniques and is based on new features of the Teaching Machine that allow third-party visualizers to be added as…
Impact of the HEALTHY study on vending machine offerings in middle schools
USDA-ARS?s Scientific Manuscript database
The purpose of this study is to report the impact of the three-year middle school-based HEALTHY study on intervention school vending machine offerings. There were two goals for the vending machines: serve only dessert/snack foods with 200 kilocalories or less per single serving package, and eliminat...
Process Monitoring Evaluation and Implementation for the Wood Abrasive Machining Process
Saloni, Daniel E.; Lemaster, Richard L.; Jackson, Steven D.
2010-01-01
Wood processing industries have continuously developed and improved technologies and processes to transform wood to obtain better final product quality and thus increase profits. Abrasive machining is one of the most important of these processes and therefore merits special attention and study. The objective of this work was to evaluate and demonstrate a process monitoring system for use in the abrasive machining of wood and wood based products. The system developed increases the life of the belt by detecting (using process monitoring sensors) and removing (by cleaning) the abrasive loading during the machining process. This study focused on abrasive belt machining processes and included substantial background work, which provided a solid base for understanding the behavior of the abrasive, and the different ways that the abrasive machining process can be monitored. In addition, the background research showed that abrasive belts can effectively be cleaned by the appropriate cleaning technique. The process monitoring system developed included acoustic emission sensors which tended to be sensitive to belt wear, as well as platen vibration, but not loading, and optical sensors which were sensitive to abrasive loading. PMID:22163477
Prediction and Validation of Disease Genes Using HeteSim Scores.
Zeng, Xiangxiang; Liao, Yuanlu; Liu, Yuansheng; Zou, Quan
2017-01-01
Deciphering the gene disease association is an important goal in biomedical research. In this paper, we use a novel relevance measure, called HeteSim, to prioritize candidate disease genes. Two methods based on heterogeneous networks constructed using protein-protein interaction, gene-phenotype associations, and phenotype-phenotype similarity, are presented. In HeteSim_MultiPath (HSMP), HeteSim scores of different paths are combined with a constant that dampens the contributions of longer paths. In HeteSim_SVM (HSSVM), HeteSim scores are combined with a machine learning method. The 3-fold experiments show that our non-machine learning method HSMP performs better than the existing non-machine learning methods, our machine learning method HSSVM obtains similar accuracy with the best existing machine learning method CATAPULT. From the analysis of the top 10 predicted genes for different diseases, we found that HSSVM avoid the disadvantage of the existing machine learning based methods, which always predict similar genes for different diseases. The data sets and Matlab code for the two methods are freely available for download at http://lab.malab.cn/data/HeteSim/index.jsp.
Hardware assisted hypervisor introspection.
Shi, Jiangyong; Yang, Yuexiang; Tang, Chuan
2016-01-01
In this paper, we introduce hypervisor introspection, an out-of-box way to monitor the execution of hypervisors. Similar to virtual machine introspection which has been proposed to protect virtual machines in an out-of-box way over the past decade, hypervisor introspection can be used to protect hypervisors which are the basis of cloud security. Virtual machine introspection tools are usually deployed either in hypervisor or in privileged virtual machines, which might also be compromised. By utilizing hardware support including nested virtualization, EPT protection and #BP, we are able to monitor all hypercalls belongs to the virtual machines of one hypervisor, include that of privileged virtual machine and even when the hypervisor is compromised. What's more, hypercall injection method is used to simulate hypercall-based attacks and evaluate the performance of our method. Experiment results show that our method can effectively detect hypercall-based attacks with some performance cost. Lastly, we discuss our furture approaches of reducing the performance cost and preventing the compromised hypervisor from detecting the existence of our introspector, in addition with some new scenarios to apply our hypervisor introspection system.
Korkmaz, Selcuk; Zararsiz, Gokmen; Goksuluk, Dincer
2015-01-01
Virtual screening is an important step in early-phase of drug discovery process. Since there are thousands of compounds, this step should be both fast and effective in order to distinguish drug-like and nondrug-like molecules. Statistical machine learning methods are widely used in drug discovery studies for classification purpose. Here, we aim to develop a new tool, which can classify molecules as drug-like and nondrug-like based on various machine learning methods, including discriminant, tree-based, kernel-based, ensemble and other algorithms. To construct this tool, first, performances of twenty-three different machine learning algorithms are compared by ten different measures, then, ten best performing algorithms have been selected based on principal component and hierarchical cluster analysis results. Besides classification, this application has also ability to create heat map and dendrogram for visual inspection of the molecules through hierarchical cluster analysis. Moreover, users can connect the PubChem database to download molecular information and to create two-dimensional structures of compounds. This application is freely available through www.biosoft.hacettepe.edu.tr/MLViS/. PMID:25928885
An efficient annealing in Boltzmann machine in Hopfield neural network
NASA Astrophysics Data System (ADS)
Kin, Teoh Yeong; Hasan, Suzanawati Abu; Bulot, Norhisam; Ismail, Mohammad Hafiz
2012-09-01
This paper proposes and implements Boltzmann machine in Hopfield neural network doing logic programming based on the energy minimization system. The temperature scheduling in Boltzmann machine enhancing the performance of doing logic programming in Hopfield neural network. The finest temperature is determined by observing the ratio of global solution and final hamming distance using computer simulations. The study shows that Boltzmann Machine model is more stable and competent in term of representing and solving difficult combinatory problems.
Tunable electromagnetically induced absorption based on graphene
NASA Astrophysics Data System (ADS)
Cao, Maoyong; Wang, Tongling; Zhang, Huiyun; Zhang, Yuping
2018-04-01
In this paper, an electronically induced absorption (EIA) structure based on graphene at the infrared frequency is proposed. A pair of nanorods is coupled to a ring resonator, resulting in electronically induced transparency (EIT), and then, Babinet's principle is applied to transform the EIT structure into an EIA structure. Based on the bright and dark modes of the coupling schemes, the adjustment of the coupling strength between the dark and bright modes can be achieved by changing the asymmetry degree. In addition, the transparency window and the absorption peak can be tuned by changing the Fermi energy of graphene. This graphene-based EIA structure can develop the path in narrow-band filtering and, absorptive switching in the future.
Wang, Zhihui; Kiryu, Tohru
2006-04-01
Since machine-based exercise still uses local facilities, it is affected by time and place. We designed a web-based system architecture based on the Java 2 Enterprise Edition that can accomplish continuously supported machine-based exercise. In this system, exercise programs and machines are loosely coupled and dynamically integrated on the site of exercise via the Internet. We then extended the conventional health promotion model, which contains three types of players (users, exercise trainers, and manufacturers), by adding a new player: exercise program creators. Moreover, we developed a self-describing strategy to accommodate a variety of exercise programs and provide ease of use to users on the web. We illustrate our novel design with examples taken from our feasibility study on a web-based cycle ergometer exercise system. A biosignal-based workload control approach was introduced to ensure that users performed appropriate exercise alone.
Teaching Machines and Programmed Instruction; an Introduction.
ERIC Educational Resources Information Center
Fry, Edward B.
Teaching machines and programed instruction represent new methods in education, but they are based on teaching principles established before the development of media technology. Today programed learning materials based on the new technology enjoy increasing popularity for several reasons: they apply sound psychological theories; the materials can…
Investigations on high speed machining of EN-353 steel alloy under different machining environments
NASA Astrophysics Data System (ADS)
Venkata Vishnu, A.; Jamaleswara Kumar, P.
2018-03-01
The addition of Nano Particles into conventional cutting fluids enhances its cooling capabilities; in the present paper an attempt is made by adding nano sized particles into conventional cutting fluids. Taguchi Robust Design Methodology is employed in order to study the performance characteristics of different turning parameters i.e. cutting speed, feed rate, depth of cut and type of tool under different machining environments i.e. dry machining, machining with lubricant - SAE 40 and machining with mixture of nano sized particles of Boric acid and base fluid SAE 40. A series of turning operations were performed using L27 (3)13 orthogonal array, considering high cutting speeds and the other machining parameters to measure hardness. The results are compared among the different machining environments, and it is concluded that there is considerable improvement in the machining performance using lubricant SAE 40 and mixture of SAE 40 + boric acid compared with dry machining. The ANOVA suggests that the selected parameters and the interactions are significant and cutting speed has most significant effect on hardness.
Nanocellulose based polymer composite for acoustical materials
NASA Astrophysics Data System (ADS)
Farid, Mohammad; Purniawan, Agung; Susanti, Diah; Priyono, Slamet; Ardhyananta, Hosta; Rahmasita, Mutia E.
2018-04-01
Natural fibers are biodegradable materials that are innovatively and widely used for composite reinforcement in automotive components. Nanocellulose derived from natural fibers oil palm empty bunches have properties that are remarkable for use as a composite reinforcement. However, there have not been many investigations related to the use of nanocellulose-based composites for wideband sound absorption materials. The specimens of nanocellulose-based polyester composite were prepared using a spray method. An impedance tube method was used to measure the sound absorption coefficient of this composite material. To reveal the characteristics of the nanocellulose-based polyester composite material, SEM (scanning electron microscope), TEM (Transmission Electron Microscope), FTIR (Fourier Transform Infra Red), TGA (Thermogravimetric Analysis), and density tests were performed. Sound absorption test results showed the average value of sound absorption coefficient of 0.36 to 0,46 for frequency between 500 and 4000 Hz indicating that this nanocellulose-based polyester composite materials had a tendency to wideband sound absorption materials and potentially used as automotive interior materials.
An Android malware detection system based on machine learning
NASA Astrophysics Data System (ADS)
Wen, Long; Yu, Haiyang
2017-08-01
The Android smartphone, with its open source character and excellent performance, has attracted many users. However, the convenience of the Android platform also has motivated the development of malware. The traditional method which detects the malware based on the signature is unable to detect unknown applications. The article proposes a machine learning-based lightweight system that is capable of identifying malware on Android devices. In this system we extract features based on the static analysis and the dynamitic analysis, then a new feature selection approach based on principle component analysis (PCA) and relief are presented in the article to decrease the dimensions of the features. After that, a model will be constructed with support vector machine (SVM) for classification. Experimental results show that our system provides an effective method in Android malware detection.
Interference effects in laser-induced plasma emission from surface-bound metal micro-particles
Feigenbaum, Eyal; Malik, Omer; Rubenchik, Alexander M.; ...
2017-04-19
Here, the light-matter interaction of an optical beam and metal micro-particulates at the vicinity of an optical substrate surface is critical to the many fields of applied optics. Examples of impacted fields are laser-induced damage in high power laser systems, sub-wavelength laser machining of transmissive materials, and laser-target interaction in directed energy applications. We present a full-wave-based model that predicts the laser-induced plasma pressure exerted on a substrate surface as a result of light absorption in surface-bound micron-scale metal particles. The model predictions agree with experimental observation of laser-induced shallow pits, formed by plasma emission and etching from surface-bound metalmore » micro-particulates. It provides an explanation for the prototypical side lobes observed along the pit profile, as well as for the dependence of the pit shape on the incident laser and particle parameters. Furthermore, the model highlights the significance of the interference of the incident light in the open cavity geometry formed between the micro-particle and the substrate in the resulting pit shape.« less
Interference effects in laser-induced plasma emission from surface-bound metal micro-particles.
Feigenbaum, Eyal; Malik, Omer; Rubenchik, Alexander M; Matthews, Manyalibo J
2017-05-01
The light-matter interaction of an optical beam and metal micro-particulates at the vicinity of an optical substrate surface is critical to the many fields of applied optics. Examples of impacted fields are laser-induced damage in high power laser systems, sub-wavelength laser machining of transmissive materials, and laser-target interaction in directed energy applications. We present a full-wave-based model that predicts the laser-induced plasma pressure exerted on a substrate surface as a result of light absorption in surface-bound micron-scale metal particles. The model predictions agree with experimental observation of laser-induced shallow pits, formed by plasma emission and etching from surface-bound metal micro-particulates. It provides an explanation for the prototypical side lobes observed along the pit profile, as well as for the dependence of the pit shape on the incident laser and particle parameters. Furthermore, the model highlights the significance of the interference of the incident light in the open cavity geometry formed between the micro-particle and the substrate in the resulting pit shape.
NASA Astrophysics Data System (ADS)
Sato, Daiki; Saitoh, Hiroumi
This paper proposes a new control method for reducing fluctuation of power system frequency through smoothing active power output of wind farm. The proposal is based on the modulation of rotaional kinetic energy of variable speed wind power generators through power converters between permanent magnet synchronous generators (PMSG) and transmission lines. In this paper, the proposed control is called Fluctuation Absorption by Flywheel Characteristics control (FAFC). The FAFC can be easily implemented by adding wind farm output signal to Maximum Power Point Tracking control signal through a feedback control loop. In order to verify the effectiveness of the FAFC control, a simulation study was carried out. In the study, it was assumed that the wind farm consisting of PMSG type wind power generator and induction machine type wind power generaotors is connected with a power sysem. The results of the study show that the FAFC control is a useful method for reducing the impacts of wind farm output fluctuation on system frequency without additional devices such as secondary battery.
NASA Astrophysics Data System (ADS)
Klose, C. D.; Kim, H. K.; Netz, U.; Blaschke, S.; Zwaka, P. A.; Mueller, G. A.; Beuthan, J.; Hielscher, A. H.
2009-02-01
Novel methods that can help in the diagnosis and monitoring of joint disease are essential for efficient use of novel arthritis therapies that are currently emerging. Building on previous studies that involved continuous wave imaging systems we present here first clinical data obtained with a new frequency-domain imaging system. Three-dimensional tomographic data sets of absorption and scattering coefficients were generated for 107 fingers. The data were analyzed using ANOVA, MANOVA, Discriminant Analysis DA, and a machine-learning algorithm that is based on self-organizing mapping (SOM) for clustering data in 2-dimensional parameter spaces. Overall we found that the SOM algorithm outperforms the more traditional analysis methods in terms of correctly classifying finger joints. Using SOM, healthy and affected joints can now be separated with a sensitivity of 0.97 and specificity of 0.91. Furthermore, preliminary results suggest that if a combination of multiple image properties is used, statistical significant differences can be found between RA-affected finger joints that show different clinical features (e.g. effusion, synovitis or erosion).
Towards a generalized energy prediction model for machine tools
Bhinge, Raunak; Park, Jinkyoo; Law, Kincho H.; Dornfeld, David A.; Helu, Moneer; Rachuri, Sudarsan
2017-01-01
Energy prediction of machine tools can deliver many advantages to a manufacturing enterprise, ranging from energy-efficient process planning to machine tool monitoring. Physics-based, energy prediction models have been proposed in the past to understand the energy usage pattern of a machine tool. However, uncertainties in both the machine and the operating environment make it difficult to predict the energy consumption of the target machine reliably. Taking advantage of the opportunity to collect extensive, contextual, energy-consumption data, we discuss a data-driven approach to develop an energy prediction model of a machine tool in this paper. First, we present a methodology that can efficiently and effectively collect and process data extracted from a machine tool and its sensors. We then present a data-driven model that can be used to predict the energy consumption of the machine tool for machining a generic part. Specifically, we use Gaussian Process (GP) Regression, a non-parametric machine-learning technique, to develop the prediction model. The energy prediction model is then generalized over multiple process parameters and operations. Finally, we apply this generalized model with a method to assess uncertainty intervals to predict the energy consumed to machine any part using a Mori Seiki NVD1500 machine tool. Furthermore, the same model can be used during process planning to optimize the energy-efficiency of a machining process. PMID:28652687
Towards a generalized energy prediction model for machine tools.
Bhinge, Raunak; Park, Jinkyoo; Law, Kincho H; Dornfeld, David A; Helu, Moneer; Rachuri, Sudarsan
2017-04-01
Energy prediction of machine tools can deliver many advantages to a manufacturing enterprise, ranging from energy-efficient process planning to machine tool monitoring. Physics-based, energy prediction models have been proposed in the past to understand the energy usage pattern of a machine tool. However, uncertainties in both the machine and the operating environment make it difficult to predict the energy consumption of the target machine reliably. Taking advantage of the opportunity to collect extensive, contextual, energy-consumption data, we discuss a data-driven approach to develop an energy prediction model of a machine tool in this paper. First, we present a methodology that can efficiently and effectively collect and process data extracted from a machine tool and its sensors. We then present a data-driven model that can be used to predict the energy consumption of the machine tool for machining a generic part. Specifically, we use Gaussian Process (GP) Regression, a non-parametric machine-learning technique, to develop the prediction model. The energy prediction model is then generalized over multiple process parameters and operations. Finally, we apply this generalized model with a method to assess uncertainty intervals to predict the energy consumed to machine any part using a Mori Seiki NVD1500 machine tool. Furthermore, the same model can be used during process planning to optimize the energy-efficiency of a machining process.
Automatic vetting of planet candidates from ground based surveys: Machine learning with NGTS
NASA Astrophysics Data System (ADS)
Armstrong, David J.; Günther, Maximilian N.; McCormac, James; Smith, Alexis M. S.; Bayliss, Daniel; Bouchy, François; Burleigh, Matthew R.; Casewell, Sarah; Eigmüller, Philipp; Gillen, Edward; Goad, Michael R.; Hodgkin, Simon T.; Jenkins, James S.; Louden, Tom; Metrailler, Lionel; Pollacco, Don; Poppenhaeger, Katja; Queloz, Didier; Raynard, Liam; Rauer, Heike; Udry, Stéphane; Walker, Simon R.; Watson, Christopher A.; West, Richard G.; Wheatley, Peter J.
2018-05-01
State of the art exoplanet transit surveys are producing ever increasing quantities of data. To make the best use of this resource, in detecting interesting planetary systems or in determining accurate planetary population statistics, requires new automated methods. Here we describe a machine learning algorithm that forms an integral part of the pipeline for the NGTS transit survey, demonstrating the efficacy of machine learning in selecting planetary candidates from multi-night ground based survey data. Our method uses a combination of random forests and self-organising-maps to rank planetary candidates, achieving an AUC score of 97.6% in ranking 12368 injected planets against 27496 false positives in the NGTS data. We build on past examples by using injected transit signals to form a training set, a necessary development for applying similar methods to upcoming surveys. We also make the autovet code used to implement the algorithm publicly accessible. autovet is designed to perform machine learned vetting of planetary candidates, and can utilise a variety of methods. The apparent robustness of machine learning techniques, whether on space-based or the qualitatively different ground-based data, highlights their importance to future surveys such as TESS and PLATO and the need to better understand their advantages and pitfalls in an exoplanetary context.
Man/Machine Interaction Dynamics And Performance (MMIDAP) capability
NASA Technical Reports Server (NTRS)
Frisch, Harold P.
1991-01-01
The creation of an ability to study interaction dynamics between a machine and its human operator can be approached from a myriad of directions. The Man/Machine Interaction Dynamics and Performance (MMIDAP) project seeks to create an ability to study the consequences of machine design alternatives relative to the performance of both machine and operator. The class of machines to which this study is directed includes those that require the intelligent physical exertions of a human operator. While Goddard's Flight Telerobotic's program was expected to be a major user, basic engineering design and biomedical applications reach far beyond telerobotics. Ongoing efforts are outlined of the GSFC and its University and small business collaborators to integrate both human performance and musculoskeletal data bases with analysis capabilities necessary to enable the study of dynamic actions, reactions, and performance of coupled machine/operator systems.
NASA Astrophysics Data System (ADS)
Drakopoulou, E.; Cowan, G. A.; Needham, M. D.; Playfer, S.; Taani, M.
2018-04-01
The application of machine learning techniques to the reconstruction of lepton energies in water Cherenkov detectors is discussed and illustrated for TITUS, a proposed intermediate detector for the Hyper-Kamiokande experiment. It is found that applying these techniques leads to an improvement of more than 50% in the energy resolution for all lepton energies compared to an approach based upon lookup tables. Machine learning techniques can be easily applied to different detector configurations and the results are comparable to likelihood-function based techniques that are currently used.
A human-machine cooperation route planning method based on improved A* algorithm
NASA Astrophysics Data System (ADS)
Zhang, Zhengsheng; Cai, Chao
2011-12-01
To avoid the limitation of common route planning method to blindly pursue higher Machine Intelligence and autoimmunization, this paper presents a human-machine cooperation route planning method. The proposed method includes a new A* path searing strategy based on dynamic heuristic searching and a human cooperated decision strategy to prune searching area. It can overcome the shortage of A* algorithm to fall into a local long term searching. Experiments showed that this method can quickly plan a feasible route to meet the macro-policy thinking.
The Integration of Project-Based Methodology into Teaching in Machine Translation
ERIC Educational Resources Information Center
Madkour, Magda
2016-01-01
This quantitative-qualitative analytical research aimed at investigating the effect of integrating project-based teaching methodology into teaching machine translation on students' performance. Data was collected from the graduate students in the College of Languages and Translation, at Imam Muhammad Ibn Saud Islamic University, Riyadh, Saudi…
[Invert transformer design for high frequency X-ray machine based on PWM controller SG 3525].
Yu, Xue-fei; Li, Zhe
2005-07-01
This paper introduces the principle of invert transformer of high frequency X-ray machine, and analyzes its main constitution. Meanwhile, a scheme based on SG3525 for closed loop voltage regulation is given. The experimental result testifies its efficiency and utility.
Chunk Alignment for Corpus-Based Machine Translation
ERIC Educational Resources Information Center
Kim, Jae Dong
2011-01-01
Since sub-sentential alignment is critically important to the translation quality of an Example-Based Machine Translation (EBMT) system, which operates by finding and combining phrase-level matches against the training examples, we developed a new alignment algorithm for the purpose of improving the EBMT system's performance. This new…
Machine Trades. A Competency Based Articulated Curriculum.
ERIC Educational Resources Information Center
Mein, Jake; And Others
This document is a competency-based curriculum guide designed to promote articulation in machine trades vocational education programs between and among secondary and postsecondary institutions in the Indian Hills Community College and Merged Area XV high schools in Iowa. The guide is organized in 11 sections. The first six sections provide…
Machinability of Stellite 6 hardfacing
NASA Astrophysics Data System (ADS)
Benghersallah, M.; Boulanouar, L.; Le Coz, G.; Devillez, A.; Dudzinski, D.
2010-06-01
This paper reports some experimental findings concerning the machinability at high cutting speed of nickel-base weld-deposited hardfacings for the manufacture of hot tooling. The forging work involves extreme impacts, forces, stresses and temperatures. Thus, mould dies must be extremely resistant. The aim of the project is to create a rapid prototyping process answering to forging conditions integrating a Stellite 6 hardfacing deposed PTA process. This study talks about the dry machining of the hardfacing, using a two tips machining tool and a high speed milling machine equipped by a power consumption recorder Wattpilote. The aim is to show the machinability of the hardfacing, measuring the power and the tip wear by optical microscope and white light interferometer, using different strategies and cutting conditions.
Investigation of Machine-ability of Inconel 800 in EDM with Coated Electrode
NASA Astrophysics Data System (ADS)
Karunakaran, K.; Chandrasekaran, M.
2017-03-01
The Inconel 800 is a high temperature application alloy which is classified as a nickel based super alloy. It has wide scope in aerospace engineering, gas Turbine etc. The machine-ability studies were found limited on this material. Hence This research focuses on machine-ability studies on EDM of Inconel 800 with Silver Coated Electrolyte Copper Electrode. The purpose of coating on electrode is to reduce tool wear. The factors pulse on Time, Pulse off Time and Peck Current were considered to observe the responses of surface roughness, material removal rate, tool wear rate. Taguchi Full Factorial Design is employed for Design the experiment. Some specific findings were reported and the percentage of contribution of each parameter was furnished
Food, gastrointestinal pH, and models of oral drug absorption.
Abuhelwa, Ahmad Y; Williams, Desmond B; Upton, Richard N; Foster, David J R
2017-03-01
This article reviews the major physiological and physicochemical principles of the effect of food and gastrointestinal (GI) pH on the absorption and bioavailability of oral drugs, and the various absorption models that are used to describe/predict oral drug absorption. The rate and extent of oral drug absorption is determined by a complex interaction between a drug's physicochemical properties, GI physiologic factors, and the nature of the formulation administered. GI pH is an important factor that can markedly affect oral drug absorption and bioavailability as it may have significant influence on drug dissolution & solubility, drug release, drug stability, and intestinal permeability. Different regions of the GI tract have different drug absorptive properties. Thus, the transit time in each GI region and its variability between subjects may contribute to the variability in the rate and/or extent of drug absorption. Food-drug interactions can result in delayed, decreased, increased, and sometimes un-altered drug absorption. Food effects on oral absorption can be achieved by direct and indirect mechanisms. Various models have been proposed to describe oral absorption ranging from empirical models to the more sophisticated "mechanism-based" models. Through understanding of the physicochemical and physiological rate-limiting factors affecting oral absorption, modellers can implement simplified population-based modelling approaches that are less complex than whole-body physiologically-based models but still capture the essential elements in a physiological way and hence will be more suited for population modelling of large clinical data sets. It will also help formulation scientists to better predict formulation performance and to develop formulations that maximize oral bioavailability. Copyright © 2016 Elsevier B.V. All rights reserved.
Oh, Jooyoung; Cho, Dongrae; Park, Jaesub; Na, Se Hee; Kim, Jongin; Heo, Jaeseok; Shin, Cheung Soo; Kim, Jae-Jin; Park, Jin Young; Lee, Boreom
2018-03-27
Delirium is an important syndrome found in patients in the intensive care unit (ICU), however, it is usually under-recognized during treatment. This study was performed to investigate whether delirious patients can be successfully distinguished from non-delirious patients by using heart rate variability (HRV) and machine learning. Electrocardiography data of 140 patients was acquired during daily ICU care, and HRV data were analyzed. Delirium, including its type, severity, and etiologies, was evaluated daily by trained psychiatrists. HRV data and various machine learning algorithms including linear support vector machine (SVM), SVM with radial basis function (RBF) kernels, linear extreme learning machine (ELM), ELM with RBF kernels, linear discriminant analysis, and quadratic discriminant analysis were utilized to distinguish delirium patients from non-delirium patients. HRV data of 4797 ECGs were included, and 39 patients had delirium at least once during their ICU stay. The maximum classification accuracy was acquired using SVM with RBF kernels. Our prediction method based on HRV with machine learning was comparable to previous delirium prediction models using massive amounts of clinical information. Our results show that autonomic alterations could be a significant feature of patients with delirium in the ICU, suggesting the potential for the automatic prediction and early detection of delirium based on HRV with machine learning.
NASA Astrophysics Data System (ADS)
Dasgupta, S.; Mukherjee, S.
2016-09-01
One of the most significant factors in metal cutting is tool life. In this research work, the effects of machining parameters on tool under wet machining environment were studied. Tool life characteristics of brazed carbide cutting tool machined against mild steel and optimization of machining parameters based on Taguchi design of experiments were examined. The experiments were conducted using three factors, spindle speed, feed rate and depth of cut each having three levels. Nine experiments were performed on a high speed semi-automatic precision central lathe. ANOVA was used to determine the level of importance of the machining parameters on tool life. The optimum machining parameter combination was obtained by the analysis of S/N ratio. A mathematical model based on multiple regression analysis was developed to predict the tool life. Taguchi's orthogonal array analysis revealed the optimal combination of parameters at lower levels of spindle speed, feed rate and depth of cut which are 550 rpm, 0.2 mm/rev and 0.5mm respectively. The Main Effects plot reiterated the same. The variation of tool life with different process parameters has been plotted. Feed rate has the most significant effect on tool life followed by spindle speed and depth of cut.
“Investigations on the machinability of Waspaloy under dry environment”
NASA Astrophysics Data System (ADS)
Deepu, J.; Kuppan, P.; SBalan, A. S.; Oyyaravelu, R.
2016-09-01
Nickel based superalloy, Waspaloy is extensively used in gas turbine, aerospace and automobile industries because of their unique combination of properties like high strength at elevated temperatures, resistance to chemical degradation and excellent wear resistance in many hostile environments. It is considered as one of the difficult to machine superalloy due to excessive tool wear and poor surface finish. The present paper is an attempt for removing cutting fluids from turning process of Waspaloy and to make the processes environmentally safe. For this purpose, the effect of machining parameters such as cutting speed and feed rate on the cutting force, cutting temperature, surface finish and tool wear were investigated barrier. Consequently, the strength and tool wear resistance and tool life increased significantly. Response Surface Methodology (RSM) has been used for developing and analyzing a mathematical model which describes the relationship between machining parameters and output variables. Subsequently ANOVA was used to check the adequacy of the regression model as well as each machining variables. The optimal cutting parameters were determined based on multi-response optimizations by composite desirability approach in order to minimize cutting force, average surface roughness and maximum flank wear. The results obtained from the experiments shown that machining of Waspaloy using coated carbide tool with special ranges of parameters, cutting fluid could be completely removed from machining process
ERIC Educational Resources Information Center
Texas State Technical Coll., Waco.
This document is intended to help education and training institutions deliver the Machine Tool Advanced Skills Technology (MAST) curriculum to a variety of individuals and organizations. MAST consists of industry-specific skill standards and model curricula for 15 occupational specialty areas within the U.S. machine tool and metals-related…
ERIC Educational Resources Information Center
Texas State Technical Coll., Waco.
This document is intended to help education and training institutions deliver the Machine Tool Advanced Skills Technology (MAST) curriculum to a variety of individuals and organizations. MAST consists of industry-specific skill standards and model curricula for 15 occupational specialty areas within the U.S. machine tool and metals-related…
ERIC Educational Resources Information Center
Texas State Technical Coll., Waco.
The Machine Tool Advanced Skills Technology (MAST) consortium was formed to address the shortage of skilled workers for the machine tools and metals-related industries. Featuring six of the nation's leading advanced technology centers, the MAST consortium developed, tested, and disseminated industry-specific skill standards and model curricula for…
ERIC Educational Resources Information Center
Texas State Technical Coll., Waco.
This volume developed by the Machine Tool Advanced Skill Technology (MAST) program contains key administrative documents and provides additional sources for machine tool and precision manufacturing information and important points of contact in the industry. The document contains the following sections: a foreword; grant award letter; timeline for…
ERIC Educational Resources Information Center
Texas State Technical Coll., Waco.
This document is intended to help education and training institutions deliver the Machine Tool Advanced Skills Technology (MAST) curriculum to a variety of individuals and organizations. MAST consists of industry-specific skill standards and model curricula for 15 occupational speciality areas within the U.S. machine tool and metals-related…
Embedded control system for computerized franking machine
NASA Astrophysics Data System (ADS)
Shi, W. M.; Zhang, L. B.; Xu, F.; Zhan, H. W.
2007-12-01
This paper presents a novel control system for franking machine. A methodology for operating a franking machine using the functional controls consisting of connection, configuration and franking electromechanical drive is studied. A set of enabling technologies to synthesize postage management software architectures driven microprocessor-based embedded systems is proposed. The cryptographic algorithm that calculates mail items is analyzed to enhance the postal indicia accountability and security. The study indicated that the franking machine is reliability, performance and flexibility in printing mail items.
Creating an Electronic Reference and Information Database for Computer-aided ECM Design
NASA Astrophysics Data System (ADS)
Nekhoroshev, M. V.; Pronichev, N. D.; Smirnov, G. V.
2018-01-01
The paper presents a review on electrochemical shaping. An algorithm has been developed to implement a computer shaping model applicable to pulse electrochemical machining. For that purpose, the characteristics of pulse current occurring in electrochemical machining of aviation materials have been studied. Based on integrating the experimental results and comprehensive electrochemical machining process data modeling, a subsystem for computer-aided design of electrochemical machining for gas turbine engine blades has been developed; the subsystem was implemented in the Teamcenter PLM system.
NASA Astrophysics Data System (ADS)
Matras, A.
2017-08-01
The paper discusses the impact of the feed screw heating on the machining accuracy. The test stand was built based on HASS Mini Mill 2 CNC milling machine and a Flir SC620 infrared camera. Measurements of workpiece were performed on Talysurf Intra 50 Taylor Hobson profilometer. The research proved that the intensive work of the milling machine lasted 60 minutes, causing thermal expansion of the feed screw what influence on the dimension error of the workpiece.
Song, Wei-Li; Zhou, Zhili; Wang, Li-Chen; Cheng, Xiao-Dong; Chen, Mingji; He, Rujie; Chen, Haosen; Yang, Yazheng; Fang, Daining
2017-12-13
Ultra-broad-band electromagnetic absorption materials and structures are increasingly attractive for their critical role in competing with the advanced broad-band electromagnetic detection systems. Mechanically soft and weak wax-based materials composites are known to be insufficient to serve in practical electromagnetic absorption applications. To break through such barriers, here we developed an innovative strategy to enable the wax-based composites to be robust and repairable meta-structures by employing a three-dimensional (3D) printed polymeric patterned shell. Because of the integrated merits from both the dielectric loss wax-based composites and mechanically robust 3D printed shells, the as-fabricated meta-structures enable bear mechanical collision and compression, coupled with ultra-broad-band absorption (7-40 and 75-110 GHz, reflection loss smaller than -10 dB) approaching state-of-the-art electromagnetic absorption materials. With the assistance of experiment and simulation methods, the design advantages and mechanism of employing such 3D printed shells for substantially promoting the electromagnetic absorption performance have been demonstrated. Therefore, such universal strategy that could be widely extended to other categories of wax-based composites highlights a smart stage on which high-performance practical multifunction meta-structures with ultra-broad-band electromagnetic absorption could be envisaged.
Parameterizing Phrase Based Statistical Machine Translation Models: An Analytic Study
ERIC Educational Resources Information Center
Cer, Daniel
2011-01-01
The goal of this dissertation is to determine the best way to train a statistical machine translation system. I first develop a state-of-the-art machine translation system called Phrasal and then use it to examine a wide variety of potential learning algorithms and optimization criteria and arrive at two very surprising results. First, despite the…
The U.S. Machine Tool Industry and the Defense Industrial Base
1983-01-01
GOLD, Director, Research Program in Industrial Economics , Case Western Reserve University HAMILTON HERMAN, Management Consultant NATHANIEL S. HOWE...Traditional U.S. Machine Tool Industry ........ 8 Technological Trends Shaping the Industry ........ 18 Economic Trends .................................. 23...sustained economic recovery and aggressive steps by both government and industry, an effectively com- petitive domestic machine tool industry can emerge
NASA Technical Reports Server (NTRS)
Warren, W. H., Jr.
1983-01-01
The machine readable catalog is described. The machine version contains the same data as the published table, which includes a second file with the notes. The computerized data files are prepared at the Astronomical Data Center. Detected discrepancies and cluster identifications based on photometric estimators are included.
Impact of the HEALTHY Study on Vending Machine Offerings in Middle Schools
ERIC Educational Resources Information Center
Hartstein, Jill; Cullen, Karen W.; Virus, Amy; El Ghormli, Laure; Volpe, Stella L.; Staten, Myrlene A.; Bridgman, Jessica C.; Stadler, Diane D.; Gillis, Bonnie; McCormick, Sarah B.; Mobley, Connie C.
2011-01-01
Purpose/Objectives: The purpose of this study is to report the impact of the three-year middle school-based HEALTHY study on intervention school vending machine offerings. There were two goals for the vending machines: serve only dessert/snack foods with 200 kilocalories or less per single serving package, and eliminate 100% fruit juice and…
Machine Tool Series. Duty Task List.
ERIC Educational Resources Information Center
Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.
This task list is intended for use in planning and/or evaluating a competency-based course to prepare machine tool, drill press, grinding machine, lathe, mill, and/or power saw operators. The listing is divided into six sections, with each one outlining the tasks required to perform the duties that have been identified for the given occupation.…
NASA Astrophysics Data System (ADS)
Ramalingam, V. V.; Pandian, A.; Jaiswal, Abhijeet; Bhatia, Nikhar
2018-04-01
This paper presents a novel method based on concept of Machine Learning for Emotion Detection using various algorithms of Support Vector Machine and major emotions described are linked to the Word-Net for enhanced accuracy. The approach proposed plays a promising role to augment the Artificial Intelligence in the near future and could be vital in optimization of Human-Machine Interface.
The compound Atwood machine problem
NASA Astrophysics Data System (ADS)
Lopes Coelho, R.
2017-05-01
The present paper accounts for progress in physics teaching in the sense that a problem, which has been closed to students for being too difficult, is gained for the high school curriculum. This problem is the compound Atwood machine with three bodies. Its introduction into high school classes is based on a recent study on the weighing of an Atwood machine.
Pesesky, Mitchell W; Hussain, Tahir; Wallace, Meghan; Patel, Sanket; Andleeb, Saadia; Burnham, Carey-Ann D; Dantas, Gautam
2016-01-01
The time-to-result for culture-based microorganism recovery and phenotypic antimicrobial susceptibility testing necessitates initial use of empiric (frequently broad-spectrum) antimicrobial therapy. If the empiric therapy is not optimal, this can lead to adverse patient outcomes and contribute to increasing antibiotic resistance in pathogens. New, more rapid technologies are emerging to meet this need. Many of these are based on identifying resistance genes, rather than directly assaying resistance phenotypes, and thus require interpretation to translate the genotype into treatment recommendations. These interpretations, like other parts of clinical diagnostic workflows, are likely to be increasingly automated in the future. We set out to evaluate the two major approaches that could be amenable to automation pipelines: rules-based methods and machine learning methods. The rules-based algorithm makes predictions based upon current, curated knowledge of Enterobacteriaceae resistance genes. The machine-learning algorithm predicts resistance and susceptibility based on a model built from a training set of variably resistant isolates. As our test set, we used whole genome sequence data from 78 clinical Enterobacteriaceae isolates, previously identified to represent a variety of phenotypes, from fully-susceptible to pan-resistant strains for the antibiotics tested. We tested three antibiotic resistance determinant databases for their utility in identifying the complete resistome for each isolate. The predictions of the rules-based and machine learning algorithms for these isolates were compared to results of phenotype-based diagnostics. The rules based and machine-learning predictions achieved agreement with standard-of-care phenotypic diagnostics of 89.0 and 90.3%, respectively, across twelve antibiotic agents from six major antibiotic classes. Several sources of disagreement between the algorithms were identified. Novel variants of known resistance factors and incomplete genome assembly confounded the rules-based algorithm, resulting in predictions based on gene family, rather than on knowledge of the specific variant found. Low-frequency resistance caused errors in the machine-learning algorithm because those genes were not seen or seen infrequently in the test set. We also identified an example of variability in the phenotype-based results that led to disagreement with both genotype-based methods. Genotype-based antimicrobial susceptibility testing shows great promise as a diagnostic tool, and we outline specific research goals to further refine this methodology.
A Novel Local Learning based Approach With Application to Breast Cancer Diagnosis
DOE Office of Scientific and Technical Information (OSTI.GOV)
Xu, Songhua; Tourassi, Georgia
2012-01-01
The purpose of this study is to develop and evaluate a novel local learning-based approach for computer-assisted diagnosis of breast cancer. Our new local learning based algorithm using the linear logistic regression method as its base learner is described. Overall, our algorithm will perform its stochastic searching process until the total allowed computing time is used up by our random walk process in identifying the most suitable population subdivision scheme and their corresponding individual base learners. The proposed local learning-based approach was applied for the prediction of breast cancer given 11 mammographic and clinical findings reported by physicians using themore » BI-RADS lexicon. Our database consisted of 850 patients with biopsy confirmed diagnosis (290 malignant and 560 benign). We also compared the performance of our method with a collection of publicly available state-of-the-art machine learning methods. Predictive performance for all classifiers was evaluated using 10-fold cross validation and Receiver Operating Characteristics (ROC) analysis. Figure 1 reports the performance of 54 machine learning methods implemented in the machine learning toolkit Weka (version 3.0). We introduced a novel local learning-based classifier and compared it with an extensive list of other classifiers for the problem of breast cancer diagnosis. Our experiments show that the algorithm superior prediction performance outperforming a wide range of other well established machine learning techniques. Our conclusion complements the existing understanding in the machine learning field that local learning may capture complicated, non-linear relationships exhibited by real-world datasets.« less
Predicting the Performance of Chain Saw Machines Based on Shore Scleroscope Hardness
NASA Astrophysics Data System (ADS)
Tumac, Deniz
2014-03-01
Shore hardness has been used to estimate several physical and mechanical properties of rocks over the last few decades. However, the number of researches correlating Shore hardness with rock cutting performance is quite limited. Also, rather limited researches have been carried out on predicting the performance of chain saw machines. This study differs from the previous investigations in the way that Shore hardness values (SH1, SH2, and deformation coefficient) are used to determine the field performance of chain saw machines. The measured Shore hardness values are correlated with the physical and mechanical properties of natural stone samples, cutting parameters (normal force, cutting force, and specific energy) obtained from linear cutting tests in unrelieved cutting mode, and areal net cutting rate of chain saw machines. Two empirical models developed previously are improved for the prediction of the areal net cutting rate of chain saw machines. The first model is based on a revised chain saw penetration index, which uses SH1, machine weight, and useful arm cutting depth as predictors. The second model is based on the power consumed for only cutting the stone, arm thickness, and specific energy as a function of the deformation coefficient. While cutting force has a strong relationship with Shore hardness values, the normal force has a weak or moderate correlation. Uniaxial compressive strength, Cerchar abrasivity index, and density can also be predicted by Shore hardness values.
Xie, Hong-Bo; Huang, Hu; Wu, Jianhua; Liu, Lei
2015-02-01
We present a multiclass fuzzy relevance vector machine (FRVM) learning mechanism and evaluate its performance to classify multiple hand motions using surface electromyographic (sEMG) signals. The relevance vector machine (RVM) is a sparse Bayesian kernel method which avoids some limitations of the support vector machine (SVM). However, RVM still suffers the difficulty of possible unclassifiable regions in multiclass problems. We propose two fuzzy membership function-based FRVM algorithms to solve such problems, based on experiments conducted on seven healthy subjects and two amputees with six hand motions. Two feature sets, namely, AR model coefficients and room mean square value (AR-RMS), and wavelet transform (WT) features, are extracted from the recorded sEMG signals. Fuzzy support vector machine (FSVM) analysis was also conducted for wide comparison in terms of accuracy, sparsity, training and testing time, as well as the effect of training sample sizes. FRVM yielded comparable classification accuracy with dramatically fewer support vectors in comparison with FSVM. Furthermore, the processing delay of FRVM was much less than that of FSVM, whilst training time of FSVM much faster than FRVM. The results indicate that FRVM classifier trained using sufficient samples can achieve comparable generalization capability as FSVM with significant sparsity in multi-channel sEMG classification, which is more suitable for sEMG-based real-time control applications.
The line-locking hypothesis, absorption by intervening galaxies, and the z = 1.95 peak in redshifts
NASA Technical Reports Server (NTRS)
Burbidge, G.
1978-01-01
The controversy over whether the absorption spectrum in QSOs is intrinsic or extrinsic is approached with attention to the peak of redshifts at z = 1.95. Also considered are the line-locking and the intervening galaxy hypotheses. The line locking hypothesis is based on observations that certain ratios found in absorption line QSOs are preferred, and leads inevitably to the conclusion that the absorption line systems are intrinsic. The intervening galaxy hypothesis is based on absorption redshifts resulting from given absorption cross-sections of galactic clusters and the intergalactic medium, and would lead to the theoretical conclusion that most QSOs show strong absorption, a conclusion which is not supported by empirical data. The 1.95 peak, on the other hand, is most probably an intrinsic property of QSOs. The peak is enhanced by redshift, and it is noted that both an emission and an absorption redshift peak are seen at 1.95.
Li, Zhi; Zhang, Zhao-hui; Zhao, Xiao-yan; Su, Hai-xia; Yan, Fang
2012-04-01
Extracting absorption spectrum in THz band is one of the important aspects in THz applications. Sample's absorption coefficient has a complex nonlinear relationship with its thickness. However, as it is not convenient to measure the thickness directly, absorption spectrum is usually determined incorrectly. Based on the method proposed by Duvillaret which was used to precisely determine the thickness of LiNbO3, the approach to measuring the absorption coefficient spectra of glutamine and histidine in frequency range from 0.3 to 2.6 THz(1 THz = 10(12) Hz) was improved in this paper. In order to validate the correctness of this absorption spectrum, we designed a series of experiments to compare the linearity of absorption coefficient belonging to one kind amino acid in different concentrations. The results indicate that as agreed by Lambert-Beer's Law, absorption coefficient spectrum of amino acid from the improved algorithm performs better linearity with its concentration than that from the common algorithm, which can be the basis of quantitative analysis in further researches.
High speed turning of compacted graphite iron using controlled modulation
NASA Astrophysics Data System (ADS)
Stalbaum, Tyler Paul
Compacted graphite iron (CGI) is a material which emerged as a candidate material to replace cast iron (CI) in the automotive industry for engine block castings. Its thermal and mechanical properties allow the CGI-based engines to operate at higher cylinder pressures and temperatures than CI-based engines, allowing for lower fuel emissions and increased fuel economy. However, these same properties together with the thermomechanical wear mode in the CGI-CBN system result in poor machinability and inhibit CGI from seeing wide spread use in the automotive industry. In industry, machining of CGI is done only at low speeds, less than V = 200 m/min, to avoid encountering rapid wear of the cutting tools during cutting. Studies have suggested intermittent cutting operations such as milling suffer less severe tool wear than continuous cutting. Furthermore, evidence that a hard sulfide layer which forms over the cutting edge in machining CI at high speeds is absent during machining CGI is a major factor in the difference in machinability of these material systems. The present study addresses both of these issues by modification to the conventional machining process to allow intermittent continuous cutting. The application of controlled modulation superimposed onto the cutting process -- modulation-assisted machining (MAM) -- is shown to be quite effective in reducing the wear of cubic boron nitride (CBN) tools when machining CGI at high machining speeds (> 500 m/min). The tool life is at least 20 times greater than found in conventional machining of CGI. This significant reduction in wear is a consequence of reduction in the severity of the tool-work contact conditions with MAM. The propensity for thermochemical wear of CBN is thus reduced. It is found that higher cutting speed (> 700 m/min) leads to lower tool wear with MAM. The MAM configuration employing feed-direction modulation appears feasible for implementation at high speeds and offers a solution to this challenging class of industrial machining applications. This study's approach is by series of high speed turning tests of CGI with CBN tools, comparing conventional machining to MAM for similar parameters otherwise, by tool wear measurements and machinability observations.
An intelligent CNC machine control system architecture
DOE Office of Scientific and Technical Information (OSTI.GOV)
Miller, D.J.; Loucks, C.S.
1996-10-01
Intelligent, agile manufacturing relies on automated programming of digitally controlled processes. Currently, processes such as Computer Numerically Controlled (CNC) machining are difficult to automate because of highly restrictive controllers and poor software environments. It is also difficult to utilize sensors and process models for adaptive control, or to integrate machining processes with other tasks within a factory floor setting. As part of a Laboratory Directed Research and Development (LDRD) program, a CNC machine control system architecture based on object-oriented design and graphical programming has been developed to address some of these problems and to demonstrate automated agile machining applications usingmore » platform-independent software.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Vanchurin, Vitaly, E-mail: vvanchur@d.umn.edu
We initiate a formal study of logical inferences in context of the measure problem in cosmology or what we call cosmic logic. We describe a simple computational model of cosmic logic suitable for analysis of, for example, discretized cosmological systems. The construction is based on a particular model of computation, developed by Alan Turing, with cosmic observers (CO), cosmic measures (CM) and cosmic symmetries (CS) described by Turing machines. CO machines always start with a blank tape and CM machines take CO's Turing number (also known as description number or Gödel number) as input and output the corresponding probability. Similarly,more » CS machines take CO's Turing number as input, but output either one if the CO machines are in the same equivalence class or zero otherwise. We argue that CS machines are more fundamental than CM machines and, thus, should be used as building blocks in constructing CM machines. We prove the non-computability of a CS machine which discriminates between two classes of CO machines: mortal that halts in finite time and immortal that runs forever. In context of eternal inflation this result implies that it is impossible to construct CM machines to compute probabilities on the set of all CO machines using cut-off prescriptions. The cut-off measures can still be used if the set is reduced to include only machines which halt after a finite and predetermined number of steps.« less
Cosmic logic: a computational model
NASA Astrophysics Data System (ADS)
Vanchurin, Vitaly
2016-02-01
We initiate a formal study of logical inferences in context of the measure problem in cosmology or what we call cosmic logic. We describe a simple computational model of cosmic logic suitable for analysis of, for example, discretized cosmological systems. The construction is based on a particular model of computation, developed by Alan Turing, with cosmic observers (CO), cosmic measures (CM) and cosmic symmetries (CS) described by Turing machines. CO machines always start with a blank tape and CM machines take CO's Turing number (also known as description number or Gödel number) as input and output the corresponding probability. Similarly, CS machines take CO's Turing number as input, but output either one if the CO machines are in the same equivalence class or zero otherwise. We argue that CS machines are more fundamental than CM machines and, thus, should be used as building blocks in constructing CM machines. We prove the non-computability of a CS machine which discriminates between two classes of CO machines: mortal that halts in finite time and immortal that runs forever. In context of eternal inflation this result implies that it is impossible to construct CM machines to compute probabilities on the set of all CO machines using cut-off prescriptions. The cut-off measures can still be used if the set is reduced to include only machines which halt after a finite and predetermined number of steps.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ruff, T.M.
1992-01-01
A prototype mucking machine designed to operate in narrow vein stopes was developed by Foster-Miller, Inc., Waltham, MA, under contract with the U.S. Bureau of Mines. The machine, called a compact loader/trammer, or minimucker, was designed to replace slusher muckers in narrow-vein underground mines. The minimucker is a six-wheel-drive, skid-steered, load-haul-dump machine that loads muck at the front with a novel slide-bucket system and ejects it out the rear so that the machine does not have to be turned around. To correct deficiencies of the tether remote control system, a computer-based, radio remote control was retrofitted to the minimucker. Initialmore » tests indicated a need to assist the operator in guiding the machine in narrow stopes and an automatic guidance system that used ultrasonic ranging sensors and a wall-following algorithm was installed. Additional tests in a simulated test stope showed that these changes improved the operation of the minimucker. The design and functions of the minimucker and its computer-based, remote control system are reviewed, and an ultrasonic, sensor-based guidance system is described.« less
Bisgin, Halil; Bera, Tanmay; Ding, Hongjian; Semey, Howard G; Wu, Leihong; Liu, Zhichao; Barnes, Amy E; Langley, Darryl A; Pava-Ripoll, Monica; Vyas, Himansu J; Tong, Weida; Xu, Joshua
2018-04-25
Insect pests, such as pantry beetles, are often associated with food contaminations and public health risks. Machine learning has the potential to provide a more accurate and efficient solution in detecting their presence in food products, which is currently done manually. In our previous research, we demonstrated such feasibility where Artificial Neural Network (ANN) based pattern recognition techniques could be implemented for species identification in the context of food safety. In this study, we present a Support Vector Machine (SVM) model which improved the average accuracy up to 85%. Contrary to this, the ANN method yielded ~80% accuracy after extensive parameter optimization. Both methods showed excellent genus level identification, but SVM showed slightly better accuracy for most species. Highly accurate species level identification remains a challenge, especially in distinguishing between species from the same genus which may require improvements in both imaging and machine learning techniques. In summary, our work does illustrate a new SVM based technique and provides a good comparison with the ANN model in our context. We believe such insights will pave better way forward for the application of machine learning towards species identification and food safety.
Machine Learning for Social Services: A Study of Prenatal Case Management in Illinois.
Pan, Ian; Nolan, Laura B; Brown, Rashida R; Khan, Romana; van der Boor, Paul; Harris, Daniel G; Ghani, Rayid
2017-06-01
To evaluate the positive predictive value of machine learning algorithms for early assessment of adverse birth risk among pregnant women as a means of improving the allocation of social services. We used administrative data for 6457 women collected by the Illinois Department of Human Services from July 2014 to May 2015 to develop a machine learning model for adverse birth prediction and improve upon the existing paper-based risk assessment. We compared different models and determined the strongest predictors of adverse birth outcomes using positive predictive value as the metric for selection. Machine learning algorithms performed similarly, outperforming the current paper-based risk assessment by up to 36%; a refined paper-based assessment outperformed the current assessment by up to 22%. We estimate that these improvements will allow 100 to 170 additional high-risk pregnant women screened for program eligibility each year to receive services that would have otherwise been unobtainable. Our analysis exhibits the potential for machine learning to move government agencies toward a more data-informed approach to evaluating risk and providing social services. Overall, such efforts will improve the efficiency of allocating resource-intensive interventions.
SAD-Based Stereo Vision Machine on a System-on-Programmable-Chip (SoPC)
Zhang, Xiang; Chen, Zhangwei
2013-01-01
This paper, proposes a novel solution for a stereo vision machine based on the System-on-Programmable-Chip (SoPC) architecture. The SOPC technology provides great convenience for accessing many hardware devices such as DDRII, SSRAM, Flash, etc., by IP reuse. The system hardware is implemented in a single FPGA chip involving a 32-bit Nios II microprocessor, which is a configurable soft IP core in charge of managing the image buffer and users' configuration data. The Sum of Absolute Differences (SAD) algorithm is used for dense disparity map computation. The circuits of the algorithmic module are modeled by the Matlab-based DSP Builder. With a set of configuration interfaces, the machine can process many different sizes of stereo pair images. The maximum image size is up to 512 K pixels. This machine is designed to focus on real time stereo vision applications. The stereo vision machine offers good performance and high efficiency in real time. Considering a hardware FPGA clock of 90 MHz, 23 frames of 640 × 480 disparity maps can be obtained in one second with 5 × 5 matching window and maximum 64 disparity pixels. PMID:23459385
Detection of inter-turn short-circuit at start-up of induction machine based on torque analysis
NASA Astrophysics Data System (ADS)
Pietrowski, Wojciech; Górny, Konrad
2017-12-01
Recently, interest in new diagnostics methods in a field of induction machines was observed. Research presented in the paper shows the diagnostics of induction machine based on torque pulsation, under inter-turn short-circuit, during start-up of a machine. In the paper three numerical techniques were used: finite element analysis, signal analysis and artificial neural networks (ANN). The elaborated numerical model of faulty machine consists of field, circuit and motion equations. Voltage excited supply allowed to determine the torque waveform during start-up. The inter-turn short-circuit was treated as a galvanic connection between two points of the stator winding. The waveforms were calculated for different amounts of shorted-turns from 0 to 55. Due to the non-stationary waveforms a wavelet packet decomposition was used to perform an analysis of the torque. The obtained results of analysis were used as input vector for ANN. The response of the neural network was the number of shorted-turns in the stator winding. Special attention was paid to compare response of general regression neural network (GRNN) and multi-layer perceptron neural network (MLP). Based on the results of the research, the efficiency of the developed algorithm can be inferred.
Fifty years of computer analysis in chest imaging: rule-based, machine learning, deep learning.
van Ginneken, Bram
2017-03-01
Half a century ago, the term "computer-aided diagnosis" (CAD) was introduced in the scientific literature. Pulmonary imaging, with chest radiography and computed tomography, has always been one of the focus areas in this field. In this study, I describe how machine learning became the dominant technology for tackling CAD in the lungs, generally producing better results than do classical rule-based approaches, and how the field is now rapidly changing: in the last few years, we have seen how even better results can be obtained with deep learning. The key differences among rule-based processing, machine learning, and deep learning are summarized and illustrated for various applications of CAD in the chest.
NASA Astrophysics Data System (ADS)
Hayden, Jakob; Hugger, Stefan; Fuchs, Frank; Lendl, Bernhard
2018-02-01
We employ a novel spectroscopic setup based on an external cavity quantum cascade laser and a Mach-Zehnder interferometer to simultaneously record spectra of absorption and dispersion of liquid samples in the mid-infrared. We describe the theory underlying the interferometric measurement and discuss its implications for the experiment. The capability of simultaneously recording a refractive index and absorption spectrum is demonstrated for a sample of acetone in cyclohexane. The recording of absorption spectra is experimentally investigated in more detail to illustrate the method's capabilities as compared to direct absorption spectroscopy. We find that absorption signals are recorded with strongly suppressed background, but with smaller absolute sensitivity. A possibility of optimizing the setup's performance by unbalancing the interferometer is presented.
A Power Transformers Fault Diagnosis Model Based on Three DGA Ratios and PSO Optimization SVM
NASA Astrophysics Data System (ADS)
Ma, Hongzhe; Zhang, Wei; Wu, Rongrong; Yang, Chunyan
2018-03-01
In order to make up for the shortcomings of existing transformer fault diagnosis methods in dissolved gas-in-oil analysis (DGA) feature selection and parameter optimization, a transformer fault diagnosis model based on the three DGA ratios and particle swarm optimization (PSO) optimize support vector machine (SVM) is proposed. Using transforming support vector machine to the nonlinear and multi-classification SVM, establishing the particle swarm optimization to optimize the SVM multi classification model, and conducting transformer fault diagnosis combined with the cross validation principle. The fault diagnosis results show that the average accuracy of test method is better than the standard support vector machine and genetic algorithm support vector machine, and the proposed method can effectively improve the accuracy of transformer fault diagnosis is proved.
Modeling the Car Crash Crisis Management System Using HiLA
NASA Astrophysics Data System (ADS)
Hölzl, Matthias; Knapp, Alexander; Zhang, Gefei
An aspect-oriented modeling approach to the Car Crash Crisis Management System (CCCMS) using the High-Level Aspect (HiLA) language is described. HiLA is a language for expressing aspects for UML static structures and UML state machines. In particular, HiLA supports both a static graph transformational and a dynamic approach of applying aspects. Furthermore, it facilitates methodologically turning use case descriptions into state machines: for each main success scenario, a base state machine is developed; all extensions to this main success scenario are covered by aspects. Overall, the static structure of the CCCMS is modeled in 43 classes, the main success scenarios in 13 base machines, the use case extensions in 47 static and 31 dynamic aspects, most of which are instantiations of simple aspect templates.
UIVerify: A Web-Based Tool for Verification and Automatic Generation of User Interfaces
NASA Technical Reports Server (NTRS)
Shiffman, Smadar; Degani, Asaf; Heymann, Michael
2004-01-01
In this poster, we describe a web-based tool for verification and automatic generation of user interfaces. The verification component of the tool accepts as input a model of a machine and a model of its interface, and checks that the interface is adequate (correct). The generation component of the tool accepts a model of a given machine and the user's task, and then generates a correct and succinct interface. This write-up will demonstrate the usefulness of the tool by verifying the correctness of a user interface to a flight-control system. The poster will include two more examples of using the tool: verification of the interface to an espresso machine, and automatic generation of a succinct interface to a large hypothetical machine.
Machine vision and appearance based learning
NASA Astrophysics Data System (ADS)
Bernstein, Alexander
2017-03-01
Smart algorithms are used in Machine vision to organize or extract high-level information from the available data. The resulted high-level understanding the content of images received from certain visual sensing system and belonged to an appearance space can be only a key first step in solving various specific tasks such as mobile robot navigation in uncertain environments, road detection in autonomous driving systems, etc. Appearance-based learning has become very popular in the field of machine vision. In general, the appearance of a scene is a function of the scene content, the lighting conditions, and the camera position. Mobile robots localization problem in machine learning framework via appearance space analysis is considered. This problem is reduced to certain regression on an appearance manifold problem, and newly regression on manifolds methods are used for its solution.
NASA Astrophysics Data System (ADS)
Zhao, Fei; Zhang, Chi; Yang, Guilin; Chen, Chinyin
2016-12-01
This paper presents an online estimation method of cutting error by analyzing of internal sensor readings. The internal sensors of numerical control (NC) machine tool are selected to avoid installation problem. The estimation mathematic model of cutting error was proposed to compute the relative position of cutting point and tool center point (TCP) from internal sensor readings based on cutting theory of gear. In order to verify the effectiveness of the proposed model, it was simulated and experimented in gear generating grinding process. The cutting error of gear was estimated and the factors which induce cutting error were analyzed. The simulation and experiments verify that the proposed approach is an efficient way to estimate the cutting error of work-piece during machining process.
NASA Astrophysics Data System (ADS)
Oksman, Antti; Kuivalainen, Kalle; Ta˚G, Carl-Mikael; Juuti, Mikko; Mattila, Rauno; Hietala, Eero; Gane, Patrick A. C.; Peiponen, Kai-Erik
2011-04-01
Gloss of a product, such as print gloss, is mainly inspected with conventional white light glossmeters both at laboratory or production facilities. However, problems occur in conventional gloss measurement when the inspected surface is vertically moved in the plane of incidence and reflection or when the measurement area is small or curved. For a partial solution to these problems, we have previously introduced diffractive optical element-based glossmeters (DOGs) for the gloss inspection in laboratories and off-line use. We present a new construction of DOG, termed μDOG 1D, for the one-dimensional on-line print gloss measurement, in the form of the reflectance determination normal to the surface. The function of the glossmeter is demonstrated by laboratory tests and on-line measurements at a heat-set web offset printing machine. It is shown that gloss (i.e., normal reflectance) and minute gloss variation of papers and prints can be measured at the printing line using the glossmeter. This glossmeter is expected to be useful in real-time monitoring of the gloss and surface-specific absorption not only in the printing industry but also in inspection of products in other industrial sectors, such as metal finishing, laminating, paper, and construction materials manufacturing.
Automation of energy demand forecasting
NASA Astrophysics Data System (ADS)
Siddique, Sanzad
Automation of energy demand forecasting saves time and effort by searching automatically for an appropriate model in a candidate model space without manual intervention. This thesis introduces a search-based approach that improves the performance of the model searching process for econometrics models. Further improvements in the accuracy of the energy demand forecasting are achieved by integrating nonlinear transformations within the models. This thesis introduces machine learning techniques that are capable of modeling such nonlinearity. Algorithms for learning domain knowledge from time series data using the machine learning methods are also presented. The novel search based approach and the machine learning models are tested with synthetic data as well as with natural gas and electricity demand signals. Experimental results show that the model searching technique is capable of finding an appropriate forecasting model. Further experimental results demonstrate an improved forecasting accuracy achieved by using the novel machine learning techniques introduced in this thesis. This thesis presents an analysis of how the machine learning techniques learn domain knowledge. The learned domain knowledge is used to improve the forecast accuracy.
Heuristic for Critical Machine Based a Lot Streaming for Two-Stage Hybrid Production Environment
NASA Astrophysics Data System (ADS)
Vivek, P.; Saravanan, R.; Chandrasekaran, M.; Pugazhenthi, R.
2017-03-01
Lot streaming in Hybrid flowshop [HFS] is encountered in many real world problems. This paper deals with a heuristic approach for Lot streaming based on critical machine consideration for a two stage Hybrid Flowshop. The first stage has two identical parallel machines and the second stage has only one machine. In the second stage machine is considered as a critical by valid reasons these kind of problems is known as NP hard. A mathematical model developed for the selected problem. The simulation modelling and analysis were carried out in Extend V6 software. The heuristic developed for obtaining optimal lot streaming schedule. The eleven cases of lot streaming were considered. The proposed heuristic was verified and validated by real time simulation experiments. All possible lot streaming strategies and possible sequence under each lot streaming strategy were simulated and examined. The heuristic consistently yielded optimal schedule consistently in all eleven cases. The identification procedure for select best lot streaming strategy was suggested.
Pre-Finishing of SiC for Optical Applications
NASA Technical Reports Server (NTRS)
Rozzi, Jay; Clavier, Odile; Gagne, John
2011-01-01
13 Manufacturing & Prototyping A method is based on two unique processing steps that are both based on deterministic machining processes using a single-point diamond turning (SPDT) machine. In the first step, a high-MRR (material removal rate) process is used to machine the part within several microns of the final geometry. In the second step, a low-MRR process is used to machine the part to near optical quality using a novel ductile regime machining (DRM) process. DRM is a deterministic machining process associated with conditions under high hydrostatic pressures and very small depths of cut. Under such conditions, using high negative-rake angle cutting tools, the high-pressure region near the tool corresponds to a plastic zone, where even a brittle material will behave in a ductile manner. In the high-MRR processing step, the objective is to remove material with a sufficiently high rate such that the process is economical, without inducing large-scale subsurface damage. A laser-assisted machining approach was evaluated whereby a CO2 laser was focused in advance of the cutting tool. While CVD (chemical vapor deposition) SiC was successfully machined with this approach, the cutting forces were substantially higher than cuts at room temperature under the same machining conditions. During the experiments, the expansion of the part and the tool due to the heating was carefully accounted for. The higher cutting forces are most likely due to a small reduction in the shear strength of the material compared with a larger increase in friction forces due to the thermal softening effect. The key advantage is that the hybrid machine approach has the potential to achieve optical quality without the need for a separate optical finishing step. Also, this method is scalable, so one can easily progress from machining 50-mm-diameter samples to the 250-mm-diameter mirror that NASA desires.
Mwangi, Benson; Ebmeier, Klaus P; Matthews, Keith; Steele, J Douglas
2012-05-01
Quantitative abnormalities of brain structure in patients with major depressive disorder have been reported at a group level for decades. However, these structural differences appear subtle in comparison with conventional radiologically defined abnormalities, with considerable inter-subject variability. Consequently, it has not been possible to readily identify scans from patients with major depressive disorder at an individual level. Recently, machine learning techniques such as relevance vector machines and support vector machines have been applied to predictive classification of individual scans with variable success. Here we describe a novel hybrid method, which combines machine learning with feature selection and characterization, with the latter aimed at maximizing the accuracy of machine learning prediction. The method was tested using a multi-centre dataset of T(1)-weighted 'structural' scans. A total of 62 patients with major depressive disorder and matched controls were recruited from referred secondary care clinical populations in Aberdeen and Edinburgh, UK. The generalization ability and predictive accuracy of the classifiers was tested using data left out of the training process. High prediction accuracy was achieved (~90%). While feature selection was important for maximizing high predictive accuracy with machine learning, feature characterization contributed only a modest improvement to relevance vector machine-based prediction (~5%). Notably, while the only information provided for training the classifiers was T(1)-weighted scans plus a categorical label (major depressive disorder versus controls), both relevance vector machine and support vector machine 'weighting factors' (used for making predictions) correlated strongly with subjective ratings of illness severity. These results indicate that machine learning techniques have the potential to inform clinical practice and research, as they can make accurate predictions about brain scan data from individual subjects. Furthermore, machine learning weighting factors may reflect an objective biomarker of major depressive disorder illness severity, based on abnormalities of brain structure.
Impact of machining on the flexural fatigue strength of glass and polycrystalline CAD/CAM ceramics.
Fraga, Sara; Amaral, Marina; Bottino, Marco Antônio; Valandro, Luiz Felipe; Kleverlaan, Cornelis Johannes; May, Liliana Gressler
2017-11-01
To assess the effect of machining on the flexural fatigue strength and on the surface roughness of different computer-aided design, computer-aided manufacturing (CAD/CAM) ceramics by comparing machined and polished after machining specimens. Disc-shaped specimens of yttria-stabilized polycrystalline tetragonal zirconia (Y-TZP), leucite-, and lithium disilicate-based glass ceramics were prepared by CAD/CAM machining, and divided into two groups: machining (M) and machining followed by polishing (MP). The surface roughness was measured and the flexural fatigue strength was evaluated by the step-test method (n=20). The initial load and the load increment for each ceramic material were based on a monotonic test (n=5). A maximum of 10,000 cycles was applied in each load step, at 1.4Hz. Weibull probability statistics was used for the analysis of the flexural fatigue strength, and Mann-Whitney test (α=5%) to compare roughness between the M and MP conditions. Machining resulted in lower values of characteristic flexural fatigue strength than machining followed by polishing. The greatest reduction in flexural fatigue strength from MP to M was observed for Y-TZP (40%; M=536.48MPa; MP=894.50MPa), followed by lithium disilicate (33%; M=187.71MPa; MP=278.93MPa) and leucite (29%; M=72.61MPa; MP=102.55MPa). Significantly higher values of roughness (Ra) were observed for M compared to MP (leucite: M=1.59μm and MP=0.08μm; lithium disilicate: M=1.84μm and MP=0.13μm; Y-TZP: M=1.79μm and MP=0.18μm). Machining negatively affected the flexural fatigue strength of CAD/CAM ceramics, indicating that machining of partially or fully sintered ceramics is deleterious to fatigue strength. Copyright © 2017 The Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Marulcu, Ismail; Barnett, Michael
2016-01-01
Background: Elementary Science Education is struggling with multiple challenges. National and State test results confirm the need for deeper understanding in elementary science education. Moreover, national policy statements and researchers call for increased exposure to engineering and technology in elementary science education. The basic motivation of this study is to suggest a solution to both improving elementary science education and increasing exposure to engineering and technology in it. Purpose/Hypothesis: This mixed-method study examined the impact of an engineering design-based curriculum compared to an inquiry-based curriculum on fifth graders' content learning of simple machines. We hypothesize that the LEGO-engineering design unit is as successful as the inquiry-based unit in terms of students' science content learning of simple machines. Design/Method: We used a mixed-methods approach to investigate our research questions; we compared the control and the experimental groups' scores from the tests and interviews by using Analysis of Covariance (ANCOVA) and compared each group's pre- and post-scores by using paired t-tests. Results: Our findings from the paired t-tests show that both the experimental and comparison groups significantly improved their scores from the pre-test to post-test on the multiple-choice, open-ended, and interview items. Moreover, ANCOVA results show that students in the experimental group, who learned simple machines with the design-based unit, performed significantly better on the interview questions. Conclusions: Our analyses revealed that the design-based Design a people mover: Simple machines unit was, if not better, as successful as the inquiry-based FOSS Levers and pulleys unit in terms of students' science content learning.
Merritt, Stephanie M; Ilgen, Daniel R
2008-04-01
We provide an empirical demonstration of the importance of attending to human user individual differences in examinations of trust and automation use. Past research has generally supported the notions that machine reliability predicts trust in automation, and trust in turn predicts automation use. However, links between user personality and perceptions of the machine with trust in automation have not been empirically established. On our X-ray screening task, 255 students rated trust and made automation use decisions while visually searching for weapons in X-ray images of luggage. We demonstrate that individual differences affect perceptions of machine characteristics when actual machine characteristics are constant, that perceptions account for 52% of trust variance above the effects of actual characteristics, and that perceptions mediate the effects of actual characteristics on trust. Importantly, we also demonstrate that when administered at different times, the same six trust items reflect two types of trust (dispositional trust and history-based trust) and that these two trust constructs are differentially related to other variables. Interactions were found among user characteristics, machine characteristics, and automation use. Our results suggest that increased specificity in the conceptualization and measurement of trust is required, future researchers should assess user perceptions of machine characteristics in addition to actual machine characteristics, and incorporation of user extraversion and propensity to trust machines can increase prediction of automation use decisions. Potential applications include the design of flexible automation training programs tailored to individuals who differ in systematic ways.
NASA Astrophysics Data System (ADS)
Liu, Shuang; Liu, Fei; Hu, Shaohua; Yin, Zhenbiao
The major power information of the main transmission system in machine tools (MTSMT) during machining process includes effective output power (i.e. cutting power), input power and power loss from the mechanical transmission system, and the main motor power loss. These information are easy to obtain in the lab but difficult to evaluate in a manufacturing process. To solve this problem, a separation method is proposed here to extract the MTSMT power information during machining process. In this method, the energy flow and the mathematical models of major power information of MTSMT during the machining process are set up first. Based on the mathematical models and the basic data tables obtained from experiments, the above mentioned power information during machining process can be separated just by measuring the real time total input power of the spindle motor. The operation program of this method is also given.
Does machine perfusion decrease ischemia reperfusion injury?
Bon, D; Delpech, P-O; Chatauret, N; Hauet, T; Badet, L; Barrou, B
2014-06-01
In 1990's, use of machine perfusion for organ preservation has been abandoned because of improvement of preservation solutions, efficient without perfusion, easy to use and cheaper. Since the last 15 years, a renewed interest for machine perfusion emerged based on studies performed on preclinical model and seems to make consensus in case of expanded criteria donors or deceased after cardiac death donations. We present relevant studies highlighted the efficiency of preservation with hypothermic machine perfusion compared to static cold storage. Machines for organ preservation being in constant evolution, we also summarized recent developments included direct oxygenation of the perfusat. Machine perfusion technology also enables organ reconditioning during the last hours of preservation through a short period of perfusion on hypothermia, subnormothermia or normothermia. We present significant or low advantages for machine perfusion against ischemia reperfusion injuries regarding at least one primary parameter: risk of DFG, organ function or graft survival. Copyright © 2014 Elsevier Masson SAS. All rights reserved.
NASA Astrophysics Data System (ADS)
Deris, A. M.; Zain, A. M.; Sallehuddin, R.; Sharif, S.
2017-09-01
Electric discharge machine (EDM) is one of the widely used nonconventional machining processes for hard and difficult to machine materials. Due to the large number of machining parameters in EDM and its complicated structural, the selection of the optimal solution of machining parameters for obtaining minimum machining performance is remain as a challenging task to the researchers. This paper proposed experimental investigation and optimization of machining parameters for EDM process on stainless steel 316L work piece using Harmony Search (HS) algorithm. The mathematical model was developed based on regression approach with four input parameters which are pulse on time, peak current, servo voltage and servo speed to the output response which is dimensional accuracy (DA). The optimal result of HS approach was compared with regression analysis and it was found HS gave better result y giving the most minimum DA value compared with regression approach.
Liu, Guohai; Yang, Junqin; Chen, Ming; Chen, Qian
2014-01-01
A fault-tolerant permanent-magnet vernier (FT-PMV) machine is designed for direct-drive applications, incorporating the merits of high torque density and high reliability. Based on the so-called magnetic gearing effect, PMV machines have the ability of high torque density by introducing the flux-modulation poles (FMPs). This paper investigates the fault-tolerant characteristic of PMV machines and provides a design method, which is able to not only meet the fault-tolerant requirements but also keep the ability of high torque density. The operation principle of the proposed machine has been analyzed. The design process and optimization are presented specifically, such as the combination of slots and poles, the winding distribution, and the dimensions of PMs and teeth. By using the time-stepping finite element method (TS-FEM), the machine performances are evaluated. Finally, the FT-PMV machine is manufactured, and the experimental results are presented to validate the theoretical analysis.
Machine learning: novel bioinformatics approaches for combating antimicrobial resistance.
Macesic, Nenad; Polubriaginof, Fernanda; Tatonetti, Nicholas P
2017-12-01
Antimicrobial resistance (AMR) is a threat to global health and new approaches to combating AMR are needed. Use of machine learning in addressing AMR is in its infancy but has made promising steps. We reviewed the current literature on the use of machine learning for studying bacterial AMR. The advent of large-scale data sets provided by next-generation sequencing and electronic health records make applying machine learning to the study and treatment of AMR possible. To date, it has been used for antimicrobial susceptibility genotype/phenotype prediction, development of AMR clinical decision rules, novel antimicrobial agent discovery and antimicrobial therapy optimization. Application of machine learning to studying AMR is feasible but remains limited. Implementation of machine learning in clinical settings faces barriers to uptake with concerns regarding model interpretability and data quality.Future applications of machine learning to AMR are likely to be laboratory-based, such as antimicrobial susceptibility phenotype prediction.
NASA Astrophysics Data System (ADS)
Li, Hui; Hong, Lu-Yao; Zhou, Qing; Yu, Hai-Jie
2015-08-01
The business failure of numerous companies results in financial crises. The high social costs associated with such crises have made people to search for effective tools for business risk prediction, among which, support vector machine is very effective. Several modelling means, including single-technique modelling, hybrid modelling, and ensemble modelling, have been suggested in forecasting business risk with support vector machine. However, existing literature seldom focuses on the general modelling frame for business risk prediction, and seldom investigates performance differences among different modelling means. We reviewed researches on forecasting business risk with support vector machine, proposed the general assisted prediction modelling frame with hybridisation and ensemble (APMF-WHAE), and finally, investigated the use of principal components analysis, support vector machine, random sampling, and group decision, under the general frame in forecasting business risk. Under the APMF-WHAE frame with support vector machine as the base predictive model, four specific predictive models were produced, namely, pure support vector machine, a hybrid support vector machine involved with principal components analysis, a support vector machine ensemble involved with random sampling and group decision, and an ensemble of hybrid support vector machine using group decision to integrate various hybrid support vector machines on variables produced from principle components analysis and samples from random sampling. The experimental results indicate that hybrid support vector machine and ensemble of hybrid support vector machines were able to produce dominating performance than pure support vector machine and support vector machine ensemble.
Survey of Commercially Available Computer-Readable Bibliographic Data Bases.
ERIC Educational Resources Information Center
Schneider, John H., Ed.; And Others
This document contains the results of a survey of 94 U. S. organizations, and 36 organizations in other countries that were thought to prepare machine-readable data bases. Of those surveyed, 55 organizations (40 in U. S., 15 in other countries) provided completed camera-ready forms describing 81 commercially available, machine-readable data bases…
Machine Learning Based Evaluation of Reading and Writing Difficulties.
Iwabuchi, Mamoru; Hirabayashi, Rumi; Nakamura, Kenryu; Dim, Nem Khan
2017-01-01
The possibility of auto evaluation of reading and writing difficulties was investigated using non-parametric machine learning (ML) regression technique for URAWSS (Understanding Reading and Writing Skills of Schoolchildren) [1] test data of 168 children of grade 1 - 9. The result showed that the ML had better prediction than the ordinary rule-based decision.
COM: Decisions and Applications in a Small University Library.
ERIC Educational Resources Information Center
Schwarz, Philip J.
Computer-output microfilm (COM) is used at the University of Wisconsin-Stout Library to generate reports from its major machine readable data bases. Conditions indicating the need to convert to COM include existence of a machine readable data base and high cost of report production. Advantages and disadvantages must also be considered before…
Effects of Toy Crane Design-Based Learning on Simple Machines
ERIC Educational Resources Information Center
Korur, Fikret; Efe, Gülfem; Erdogan, Fisun; Tunç, Berna
2017-01-01
The aim of this 2-group study was to investigate the following question: Are there significant differences between scaffolded design-based learning controlled using 7 forms and teacher-directed instruction methods for the toy crane project on grade 7 students' posttest scores on the simple machines achievement test, attitude toward simple…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lu, Siyuan; Hwang, Youngdeok; Khabibrakhmanov, Ildar
With increasing penetration of solar and wind energy to the total energy supply mix, the pressing need for accurate energy forecasting has become well-recognized. Here we report the development of a machine-learning based model blending approach for statistically combining multiple meteorological models for improving the accuracy of solar/wind power forecast. Importantly, we demonstrate that in addition to parameters to be predicted (such as solar irradiance and power), including additional atmospheric state parameters which collectively define weather situations as machine learning input provides further enhanced accuracy for the blended result. Functional analysis of variance shows that the error of individual modelmore » has substantial dependence on the weather situation. The machine-learning approach effectively reduces such situation dependent error thus produces more accurate results compared to conventional multi-model ensemble approaches based on simplistic equally or unequally weighted model averaging. Validation over an extended period of time results show over 30% improvement in solar irradiance/power forecast accuracy compared to forecasts based on the best individual model.« less
Solti, Imre; Cooke, Colin R; Xia, Fei; Wurfel, Mark M
2009-11-01
This paper compares the performance of keyword and machine learning-based chest x-ray report classification for Acute Lung Injury (ALI). ALI mortality is approximately 30 percent. High mortality is, in part, a consequence of delayed manual chest x-ray classification. An automated system could reduce the time to recognize ALI and lead to reductions in mortality. For our study, 96 and 857 chest x-ray reports in two corpora were labeled by domain experts for ALI. We developed a keyword and a Maximum Entropy-based classification system. Word unigram and character n-grams provided the features for the machine learning system. The Maximum Entropy algorithm with character 6-gram achieved the highest performance (Recall=0.91, Precision=0.90 and F-measure=0.91) on the 857-report corpus. This study has shown that for the classification of ALI chest x-ray reports, the machine learning approach is superior to the keyword based system and achieves comparable results to highest performing physician annotators.
Solti, Imre; Cooke, Colin R.; Xia, Fei; Wurfel, Mark M.
2010-01-01
This paper compares the performance of keyword and machine learning-based chest x-ray report classification for Acute Lung Injury (ALI). ALI mortality is approximately 30 percent. High mortality is, in part, a consequence of delayed manual chest x-ray classification. An automated system could reduce the time to recognize ALI and lead to reductions in mortality. For our study, 96 and 857 chest x-ray reports in two corpora were labeled by domain experts for ALI. We developed a keyword and a Maximum Entropy-based classification system. Word unigram and character n-grams provided the features for the machine learning system. The Maximum Entropy algorithm with character 6-gram achieved the highest performance (Recall=0.91, Precision=0.90 and F-measure=0.91) on the 857-report corpus. This study has shown that for the classification of ALI chest x-ray reports, the machine learning approach is superior to the keyword based system and achieves comparable results to highest performing physician annotators. PMID:21152268
Knowledge-based vision and simple visual machines.
Cliff, D; Noble, J
1997-01-01
The vast majority of work in machine vision emphasizes the representation of perceived objects and events: it is these internal representations that incorporate the 'knowledge' in knowledge-based vision or form the 'models' in model-based vision. In this paper, we discuss simple machine vision systems developed by artificial evolution rather than traditional engineering design techniques, and note that the task of identifying internal representations within such systems is made difficult by the lack of an operational definition of representation at the causal mechanistic level. Consequently, we question the nature and indeed the existence of representations posited to be used within natural vision systems (i.e. animals). We conclude that representations argued for on a priori grounds by external observers of a particular vision system may well be illusory, and are at best place-holders for yet-to-be-identified causal mechanistic interactions. That is, applying the knowledge-based vision approach in the understanding of evolved systems (machines or animals) may well lead to theories and models that are internally consistent, computationally plausible, and entirely wrong. PMID:9304684
NASA Astrophysics Data System (ADS)
Koten, V. K.; Tanamal, C. E.
2017-03-01
Manufacturing agricultural products by the farmers, people or person who involve in medium industry, small industry, and households industry still be done in separately. Although the power on primemover is enough, in operations, primemover was only to move one of several agricultural products machine. This study attempts to design and construct power transmition multi output with single primemover; a single construction that allows primemover move some agricultur products machine in the same or not. This study begins with the determination of production capacity and the power to destroy products, the determination of resources and rotation, normalization of resources and rotation, the determination of the type material used, the size determination of each machine elements, construction machine elements, and assemble machine elements into a construction multi output power transmition with single primemover on agricultural products machine. The results show that with a input normalization 4 PK (2984 Watt), rotation 2000 rpm, the strength of material 60 kg/mm2, and several operating consideration, thus obtained size of machine elements through calculation. Based on the size, the machine elements is made through the use of some machine tools and assembled to form a multi output power transmition with single primemover.
DOE-RCT-0003641 Final Technical Report
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wagner, Edward; Lesster, Ted
2014-07-30
This program studied novel concepts for an Axial Flux Reluctance Machine to capture energy from marine hydrokinetic sources and compared their attributes to a Radial Flux Reluctance Machine which was designed under a prior Department of Energy program for the same application. Detailed electromagnetic and mechanical analyses were performed to determine the validity of the concept and to provide a direct comparison with the existing conventional Radial Flux Switched Reluctance Machine designed during the Advanced Wave Energy Conversion Project, DE-EE0003641. The alternate design changed the machine topology so that the flux that is switched flows axially rather than radially andmore » the poles themselves are long radially, as opposed to the radial flux machine that has pole pieces that are long axially. It appeared possible to build an axial flux machine that should be considerably more compact than the radial machine. In an “apples to apples” comparison, the same rules with regard to generating magnetic force and the fundamental limitations of flux density hold, so that at the heart of the machine the same torque equations hold. The differences are in the mechanical configuration that limits or enhances the change of permeance with rotor position, in the amount of permeable iron required to channel the flux via the pole pieces to the air-gaps, and in the sizing and complexity of the electrical winding. Accordingly it was anticipated that the magnetic component weight would be similar but that better use of space would result in a shorter machine with accompanying reduction in housing and support structure. For the comparison the pole count was kept the same at 28 though it was also expected that the radial tapering of the slots between pole pieces would permit a higher pole count machine, enabling the generation of greater power at a given speed in some future design. The baseline Radial Flux Machine design was established during the previous DOE program. Its characteristics were tabulated for use in comparing to the Axial Flux Machine. Three basic conceptual designs for the Axial Flux Machine were considered: (1) a machine with a single coil at the inner diameter of the machine, (2) a machine with a single coil at the outside diameter of the machine, and (3) a machine with a coil around each tooth. Slight variations of these basic configurations were considered during the study. Analysis was performed on these configurations to determine the best candidate design to advance to preliminary design, based on size, weight, performance, cost and manufacturability. The configuration selected as the most promising was the multi-pole machine with a coil around each tooth. This configuration provided the least complexity with respect to the mechanical configuration and manufacturing, which would yield the highest reliability and lowest cost machine of the three options. A preliminary design was performed on this selected configuration. For this first ever axial design of the multi rotor configuration the 'apples to apples' comparison was based on using the same length of rotor pole as the axial length of rotor pole in the radial machine and making the mean radius of the rotor in the axial machine the same as the air gap radius in the radial machine. The tooth to slot ratio at the mean radius of the axial machine was the same as the tooth to slot ratio of the radial machine. The comparison between the original radial flux machine and the new axial flux machine indicates that for the same torque, the axial flux machine diameter will be 27% greater, but it will have 30% of the length, and 76% of the weight. Based on these results, it is concluded that an axial flux reluctance machine presents a viable option for large generators to be used for the capture of wave energy. In the analysis of Task 4, below, it is pointed out that our selection of dimensional similarity for the 'apples to apples' comparison did not produce an optimum axial flux design. There is torque capability to spare, implying we could reduce the magnetic structure, but the winding area, constrained by the pole separation at the inner pole radius has a higher resistance than desirable, implying we need more room for copper. The recommendation is to proceed via one cycle of optimization and review to correct this unbalance and then proceed to a detailed design phase to produce manufacturing drawings, followed by the construction of a prototype to test the performance of the machine against predicted results.« less
NASA Astrophysics Data System (ADS)
Sohrabi, Mahmoud Reza; Darabi, Golnaz
2016-01-01
Flavonoids are γ-benzopyrone derivatives, which are highly regarded in these researchers for their antioxidant property. In this study, two new signals processing methods been coupled with UV spectroscopy for spectral resolution and simultaneous quantitative determination of Myricetin, Kaempferol and Quercetin as flavonoids in Laurel, St. John's Wort and Green Tea without the need for any previous separation procedure. The developed methods are continuous wavelet transform (CWT) and least squares support vector machine (LS-SVM) methods integrated with UV spectroscopy individually. Different wavelet families were tested by CWT method and finally the Daubechies wavelet family (Db4) for Myricetin and the Gaussian wavelet families for Kaempferol (Gaus3) and Quercetin (Gaus7) were selected and applied for simultaneous analysis under the optimal conditions. The LS-SVM was applied to build the flavonoids prediction model based on absorption spectra. The root mean square errors for prediction (RMSEP) of Myricetin, Kaempferol and Quercetin were 0.0552, 0.0275 and 0.0374, respectively. The developed methods were validated by the analysis of the various synthetic mixtures associated with a well- known flavonoid contents. Mean recovery values of Myricetin, Kaempferol and Quercetin, in CWT method were 100.123, 100.253, 100.439 and in LS-SVM method were 99.94, 99.81 and 99.682, respectively. The results achieved by analyzing the real samples from the CWT and LS-SVM methods were compared to the HPLC reference method and the results were very close to the reference method. Meanwhile, the obtained results of the one-way ANOVA (analysis of variance) test revealed that there was no significant difference between the suggested methods.
ChariDingari, Narahara; Barman, Ishan; Myakalwar, Ashwin Kumar; Tewari, Surya P.; Kumar, G. Manoj
2012-01-01
Despite the intrinsic elemental analysis capability and lack of sample preparation requirements, laser-induced breakdown spectroscopy (LIBS) has not been extensively used for real world applications, e.g. quality assurance and process monitoring. Specifically, variability in sample, system and experimental parameters in LIBS studies present a substantive hurdle for robust classification, even when standard multivariate chemometric techniques are used for analysis. Considering pharmaceutical sample investigation as an example, we propose the use of support vector machines (SVM) as a non-linear classification method over conventional linear techniques such as soft independent modeling of class analogy (SIMCA) and partial least-squares discriminant analysis (PLS-DA) for discrimination based on LIBS measurements. Using over-the-counter pharmaceutical samples, we demonstrate that application of SVM enables statistically significant improvements in prospective classification accuracy (sensitivity), due to its ability to address variability in LIBS sample ablation and plasma self-absorption behavior. Furthermore, our results reveal that SVM provides nearly 10% improvement in correct allocation rate and a concomitant reduction in misclassification rates of 75% (cf. PLS-DA) and 80% (cf. SIMCA)-when measurements from samples not included in the training set are incorporated in the test data – highlighting its robustness. While further studies on a wider matrix of sample types performed using different LIBS systems is needed to fully characterize the capability of SVM to provide superior predictions, we anticipate that the improved sensitivity and robustness observed here will facilitate application of the proposed LIBS-SVM toolbox for screening drugs and detecting counterfeit samples as well as in related areas of forensic and biological sample analysis. PMID:22292496
Dingari, Narahara Chari; Barman, Ishan; Myakalwar, Ashwin Kumar; Tewari, Surya P; Kumar Gundawar, Manoj
2012-03-20
Despite the intrinsic elemental analysis capability and lack of sample preparation requirements, laser-induced breakdown spectroscopy (LIBS) has not been extensively used for real-world applications, e.g., quality assurance and process monitoring. Specifically, variability in sample, system, and experimental parameters in LIBS studies present a substantive hurdle for robust classification, even when standard multivariate chemometric techniques are used for analysis. Considering pharmaceutical sample investigation as an example, we propose the use of support vector machines (SVM) as a nonlinear classification method over conventional linear techniques such as soft independent modeling of class analogy (SIMCA) and partial least-squares discriminant analysis (PLS-DA) for discrimination based on LIBS measurements. Using over-the-counter pharmaceutical samples, we demonstrate that the application of SVM enables statistically significant improvements in prospective classification accuracy (sensitivity), because of its ability to address variability in LIBS sample ablation and plasma self-absorption behavior. Furthermore, our results reveal that SVM provides nearly 10% improvement in correct allocation rate and a concomitant reduction in misclassification rates of 75% (cf. PLS-DA) and 80% (cf. SIMCA)-when measurements from samples not included in the training set are incorporated in the test data-highlighting its robustness. While further studies on a wider matrix of sample types performed using different LIBS systems is needed to fully characterize the capability of SVM to provide superior predictions, we anticipate that the improved sensitivity and robustness observed here will facilitate application of the proposed LIBS-SVM toolbox for screening drugs and detecting counterfeit samples, as well as in related areas of forensic and biological sample analysis.
Sohrabi, Mahmoud Reza; Darabi, Golnaz
2016-01-05
Flavonoids are γ-benzopyrone derivatives, which are highly regarded in these researchers for their antioxidant property. In this study, two new signals processing methods been coupled with UV spectroscopy for spectral resolution and simultaneous quantitative determination of Myricetin, Kaempferol and Quercetin as flavonoids in Laurel, St. John's Wort and Green Tea without the need for any previous separation procedure. The developed methods are continuous wavelet transform (CWT) and least squares support vector machine (LS-SVM) methods integrated with UV spectroscopy individually. Different wavelet families were tested by CWT method and finally the Daubechies wavelet family (Db4) for Myricetin and the Gaussian wavelet families for Kaempferol (Gaus3) and Quercetin (Gaus7) were selected and applied for simultaneous analysis under the optimal conditions. The LS-SVM was applied to build the flavonoids prediction model based on absorption spectra. The root mean square errors for prediction (RMSEP) of Myricetin, Kaempferol and Quercetin were 0.0552, 0.0275 and 0.0374, respectively. The developed methods were validated by the analysis of the various synthetic mixtures associated with a well- known flavonoid contents. Mean recovery values of Myricetin, Kaempferol and Quercetin, in CWT method were 100.123, 100.253, 100.439 and in LS-SVM method were 99.94, 99.81 and 99.682, respectively. The results achieved by analyzing the real samples from the CWT and LS-SVM methods were compared to the HPLC reference method and the results were very close to the reference method. Meanwhile, the obtained results of the one-way ANOVA (analysis of variance) test revealed that there was no significant difference between the suggested methods. Copyright © 2015 Elsevier B.V. All rights reserved.
Enhanced Learning through Design Problems--Teaching a Components-Based Course through Design
ERIC Educational Resources Information Center
Jensen, Bogi Bech; Hogberg, Stig; Jensen, Frida av Flotum; Mijatovic, Nenad
2012-01-01
This paper describes a teaching method used in an electrical machines course, where the students learn about electrical machines by designing them. The aim of the course is not to teach design, albeit this is a side product, but rather to teach the fundamentals and the function of electrical machines through design. The teaching method is…
ERIC Educational Resources Information Center
Kocken, Paul L.; Eeuwijk, Jennifer; van Kesteren, Nicole M.C.; Dusseldorp, Elise; Buijs, Goof; Bassa-Dafesh, Zeina; Snel, Jeltje
2012-01-01
Background: Vending machines account for food sales and revenue in schools. We examined 3 strategies for promoting the sale of lower-calorie food products from vending machines in high schools in the Netherlands. Methods: A school-based randomized controlled trial was conducted in 13 experimental schools and 15 control schools. Three strategies…
A Machine Vision System for Automatically Grading Hardwood Lumber - (Proceedings)
Richard W. Conners; Tai-Hoon Cho; Chong T. Ng; Thomas H. Drayer; Joe G. Tront; Philip A. Araman; Robert L. Brisbon
1990-01-01
Any automatic system for grading hardwood lumber can conceptually be divided into two components. One of these is a machine vision system for locating and identifying grading defects. The other is an automatic grading program that accepts as input the output of the machine vision system and, based on these data, determines the grade of a board. The progress that has...
Machine learning approaches in medical image analysis: From detection to diagnosis.
de Bruijne, Marleen
2016-10-01
Machine learning approaches are increasingly successful in image-based diagnosis, disease prognosis, and risk assessment. This paper highlights new research directions and discusses three main challenges related to machine learning in medical imaging: coping with variation in imaging protocols, learning from weak labels, and interpretation and evaluation of results. Copyright © 2016 Elsevier B.V. All rights reserved.
ERIC Educational Resources Information Center
Emig, Brandon R.; McDonald, Scott; Zembal-Saul, Carla; Strauss, Susan G.
2014-01-01
This study invited small groups to make several arguments by analogy about simple machines. Groups were first provided training on analogical (structure) mapping and were then invited to use analogical mapping as a scaffold to make arguments. In making these arguments, groups were asked to consider three simple machines: two machines that they had…
Does Machine-Readable Documentation on Online Hosts and CD-ROMs Have a Role or Future?
ERIC Educational Resources Information Center
Harris, Stephen; Oppenheim, Charles
1996-01-01
Reports results of a United Kingdom-based mail survey of database users, CD-ROM producers, and hosts to assess trends and views concerning documentation in machine-readable form. Cost, convenience, and ease of use of print manuals are cited as reasons for the reluctance to switch to machine-readable documentation. Sample surveys are included.…
SBS vs Inhouse Recycling Methods-An Invitro Evaluation
Verma, Jaya Krishanan; Arun; Sundari, Shanta; Chandrasekhar, Shyamala; Kumar, Aravind
2015-01-01
Introduction In today’s world of economic crisis it is not feasible for an orthodontist to replace each and every debonded bracket with a new bracket- quest for an alternative thrives Orthodontist. The concept of recycling bracket for its reuse has evolved over a period of time. Orthodontist can send the brackets to various commercial recycling companies for recycling, but it’s impractical as these are complex procedures and require time and usage of a new bracket would seem more feasible. Thereby, in-house methods have been developed. The aim of the study was to determine the SBS (Shear Bond Strength) and to compare, evaluate the efficiency of in house recycling methods with that of the SBS of new brackets. Materials and Methods Five in–house-recycling procedures-Adhesive Grinding Method, Sandblasting Method, Thermal Flaming Method, Buchman method and Acid Bath Method were used in the present study. Initial part of the study included the use of UV/Vis spectrophotometer where in the absorption level of base of new stainless steel bracket is compared with the base of a recycled bracket. The difference seen in the UV absorbance can be attributed to the presence of adhesive remnant. For each recycling procedure the difference in UV absorption is calculated. New stainless steel brackets and recycled brackets were tested for its shear bond strength with Instron testing machine. Comparisons were made between shear bond strength of new brackets with that of recycled brackets. The last part of the study involved correlating the findings of UV/Vis spectrophotometer with the shear bond strength for each recycling procedure. Results Among the recycled brackets the Sandblasting technique showed the highest shear bond strength (19.789MPa) and the least was shown by the Adhesive Grinding method (13.809MPa). Conclusion The study concludes that sand blasting can be an effective choice among the 5 in house methods of recycling methods. PMID:26501002
Nizam, A; Mohamed, S H; Arifin, A; Mohd Ishak, Z A; Samsudin, A R
2004-05-01
The aim of this study was to evaluate the tensile properties and water absorption of denture base material prepared from high molecular weight poly methyl methacrylate (PMMA) and alumina (Al2O3) as particulate filler. Specimens for mechanical testing were prepared by adding composite powder to the monomer followed by hand mixing as in dental laboratory procedure. The tensile strength of the prepared denture base material was slightly higher than commercial denture base material, while the water absorption was almost the same for all formulation of denture base materials.
Time-dependent oral absorption models
NASA Technical Reports Server (NTRS)
Higaki, K.; Yamashita, S.; Amidon, G. L.
2001-01-01
The plasma concentration-time profiles following oral administration of drugs are often irregular and cannot be interpreted easily with conventional models based on first- or zero-order absorption kinetics and lag time. Six new models were developed using a time-dependent absorption rate coefficient, ka(t), wherein the time dependency was varied to account for the dynamic processes such as changes in fluid absorption or secretion, in absorption surface area, and in motility with time, in the gastrointestinal tract. In the present study, the plasma concentration profiles of propranolol obtained in human subjects following oral dosing were analyzed using the newly derived models based on mass balance and compared with the conventional models. Nonlinear regression analysis indicated that the conventional compartment model including lag time (CLAG model) could not predict the rapid initial increase in plasma concentration after dosing and the predicted Cmax values were much lower than that observed. On the other hand, all models with the time-dependent absorption rate coefficient, ka(t), were superior to the CLAG model in predicting plasma concentration profiles. Based on Akaike's Information Criterion (AIC), the fluid absorption model without lag time (FA model) exhibited the best overall fit to the data. The two-phase model including lag time, TPLAG model was also found to be a good model judging from the values of sum of squares. This model also described the irregular profiles of plasma concentration with time and frequently predicted Cmax values satisfactorily. A comparison of the absorption rate profiles also suggested that the TPLAG model is better at prediction of irregular absorption kinetics than the FA model. In conclusion, the incorporation of a time-dependent absorption rate coefficient ka(t) allows the prediction of nonlinear absorption characteristics in a more reliable manner.
Machine Vision-Based Measurement Systems for Fruit and Vegetable Quality Control in Postharvest.
Blasco, José; Munera, Sandra; Aleixos, Nuria; Cubero, Sergio; Molto, Enrique
Individual items of any agricultural commodity are different from each other in terms of colour, shape or size. Furthermore, as they are living thing, they change their quality attributes over time, thereby making the development of accurate automatic inspection machines a challenging task. Machine vision-based systems and new optical technologies make it feasible to create non-destructive control and monitoring tools for quality assessment to ensure adequate accomplishment of food standards. Such systems are much faster than any manual non-destructive examination of fruit and vegetable quality, thus allowing the whole production to be inspected with objective and repeatable criteria. Moreover, current technology makes it possible to inspect the fruit in spectral ranges beyond the sensibility of the human eye, for instance in the ultraviolet and near-infrared regions. Machine vision-based applications require the use of multiple technologies and knowledge, ranging from those related to image acquisition (illumination, cameras, etc.) to the development of algorithms for spectral image analysis. Machine vision-based systems for inspecting fruit and vegetables are targeted towards different purposes, from in-line sorting into commercial categories to the detection of contaminants or the distribution of specific chemical compounds on the product's surface. This chapter summarises the current state of the art in these techniques, starting with systems based on colour images for the inspection of conventional colour, shape or external defects and then goes on to consider recent developments in spectral image analysis for internal quality assessment or contaminant detection.
Interpreting support vector machine models for multivariate group wise analysis in neuroimaging
Gaonkar, Bilwaj; Shinohara, Russell T; Davatzikos, Christos
2015-01-01
Machine learning based classification algorithms like support vector machines (SVMs) have shown great promise for turning a high dimensional neuroimaging data into clinically useful decision criteria. However, tracing imaging based patterns that contribute significantly to classifier decisions remains an open problem. This is an issue of critical importance in imaging studies seeking to determine which anatomical or physiological imaging features contribute to the classifier’s decision, thereby allowing users to critically evaluate the findings of such machine learning methods and to understand disease mechanisms. The majority of published work addresses the question of statistical inference for support vector classification using permutation tests based on SVM weight vectors. Such permutation testing ignores the SVM margin, which is critical in SVM theory. In this work we emphasize the use of a statistic that explicitly accounts for the SVM margin and show that the null distributions associated with this statistic are asymptotically normal. Further, our experiments show that this statistic is a lot less conservative as compared to weight based permutation tests and yet specific enough to tease out multivariate patterns in the data. Thus, we can better understand the multivariate patterns that the SVM uses for neuroimaging based classification. PMID:26210913
A Novel Acoustic Sensor Approach to Classify Seeds Based on Sound Absorption Spectra
Gasso-Tortajada, Vicent; Ward, Alastair J.; Mansur, Hasib; Brøchner, Torben; Sørensen, Claus G.; Green, Ole
2010-01-01
A non-destructive and novel in situ acoustic sensor approach based on the sound absorption spectra was developed for identifying and classifying different seed types. The absorption coefficient spectra were determined by using the impedance tube measurement method. Subsequently, a multivariate statistical analysis, i.e., principal component analysis (PCA), was performed as a way to generate a classification of the seeds based on the soft independent modelling of class analogy (SIMCA) method. The results show that the sound absorption coefficient spectra of different seed types present characteristic patterns which are highly dependent on seed size and shape. In general, seed particle size and sphericity were inversely related with the absorption coefficient. PCA presented reliable grouping capabilities within the diverse seed types, since the 95% of the total spectral variance was described by the first two principal components. Furthermore, the SIMCA classification model based on the absorption spectra achieved optimal results as 100% of the evaluation samples were correctly classified. This study contains the initial structuring of an innovative method that will present new possibilities in agriculture and industry for classifying and determining physical properties of seeds and other materials. PMID:22163455
8. Credit USAF, ca. 1945. Original housed in the Muroc ...
8. Credit USAF, ca. 1945. Original housed in the Muroc Flight Test Base, Unit History, 1 September 1942 - 30 June 1945. Alfred F. Simpson Historical Research Agency. United States Air Force. Maxwell AFB, Alabama. View of concrete base for jet engine rotor balancing machine. Location where photograph was taken not determined, but presumed to be in shops of Building 4505 which had a sizeable machine shop. - Edwards Air Force Base, North Base, Hangar, End of North Base Road, Boron, Kern County, CA
Araki, Tadashi; Ikeda, Nobutaka; Shukla, Devarshi; Jain, Pankaj K; Londhe, Narendra D; Shrivastava, Vimal K; Banchhor, Sumit K; Saba, Luca; Nicolaides, Andrew; Shafique, Shoaib; Laird, John R; Suri, Jasjit S
2016-05-01
Percutaneous coronary interventional procedures need advance planning prior to stenting or an endarterectomy. Cardiologists use intravascular ultrasound (IVUS) for screening, risk assessment and stratification of coronary artery disease (CAD). We hypothesize that plaque components are vulnerable to rupture due to plaque progression. Currently, there are no standard grayscale IVUS tools for risk assessment of plaque rupture. This paper presents a novel strategy for risk stratification based on plaque morphology embedded with principal component analysis (PCA) for plaque feature dimensionality reduction and dominant feature selection technique. The risk assessment utilizes 56 grayscale coronary features in a machine learning framework while linking information from carotid and coronary plaque burdens due to their common genetic makeup. This system consists of a machine learning paradigm which uses a support vector machine (SVM) combined with PCA for optimal and dominant coronary artery morphological feature extraction. Carotid artery proven intima-media thickness (cIMT) biomarker is adapted as a gold standard during the training phase of the machine learning system. For the performance evaluation, K-fold cross validation protocol is adapted with 20 trials per fold. For choosing the dominant features out of the 56 grayscale features, a polling strategy of PCA is adapted where the original value of the features is unaltered. Different protocols are designed for establishing the stability and reliability criteria of the coronary risk assessment system (cRAS). Using the PCA-based machine learning paradigm and cross-validation protocol, a classification accuracy of 98.43% (AUC 0.98) with K=10 folds using an SVM radial basis function (RBF) kernel was achieved. A reliability index of 97.32% and machine learning stability criteria of 5% were met for the cRAS. This is the first Computer aided design (CADx) system of its kind that is able to demonstrate the ability of coronary risk assessment and stratification while demonstrating a successful design of the machine learning system based on our assumptions. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
Fuzzy Logic-Based Audio Pattern Recognition
NASA Astrophysics Data System (ADS)
Malcangi, M.
2008-11-01
Audio and audio-pattern recognition is becoming one of the most important technologies to automatically control embedded systems. Fuzzy logic may be the most important enabling methodology due to its ability to rapidly and economically model such application. An audio and audio-pattern recognition engine based on fuzzy logic has been developed for use in very low-cost and deeply embedded systems to automate human-to-machine and machine-to-machine interaction. This engine consists of simple digital signal-processing algorithms for feature extraction and normalization, and a set of pattern-recognition rules manually tuned or automatically tuned by a self-learning process.
A 34-meter VAWT (Vertical Axis Wind Turbine) point design
NASA Astrophysics Data System (ADS)
Ashwill, T. D.; Berg, D. E.; Dodd, H. M.; Rumsey, M. A.; Sutherland, H. J.; Veers, P. S.
The Wind Energy Division at Sandia National Laboratories recently completed a point design based on the 34-m Vertical Axis Wind Turbine (VAWT) Test Bed. The 34-m Test Bed research machine incorporates several innovations that improve Darrieus technology, including increased energy production, over previous machines. The point design differs minimally from the Test Bed; but by removing research-related items, its estimated cost is substantially reduced. The point design is a first step towards a Test-Bed-based commercial machine that would be competitive with conventional sources of power in the mid-1990s.
Design of robotic cells based on relative handling modules with use of SolidWorks system
NASA Astrophysics Data System (ADS)
Gaponenko, E. V.; Anciferov, S. I.
2018-05-01
The article presents a diagramed engineering solution for a robotic cell with six degrees of freedom for machining of complex details, consisting of the base with a tool installation module and a detail machining module made as parallel structure mechanisms. The output links of the detail machining module and the tool installation module can move along X-Y-Z coordinate axes each. A 3D-model of the complex is designed in the SolidWorks system. It will be used further for carrying out engineering calculations and mathematical analysis and obtaining all required documentation.
NASA Astrophysics Data System (ADS)
Utegulov, B. B.; Utegulov, A. B.; Meiramova, S.
2018-02-01
The paper proposes the development of a self-learning machine for creating models of microprocessor-based single-phase ground fault protection devices in networks with an isolated neutral voltage higher than 1000 V. Development of a self-learning machine for creating models of microprocessor-based single-phase earth fault protection devices in networks with an isolated neutral voltage higher than 1000 V. allows to effectively implement mathematical models of automatic change of protection settings. Single-phase earth fault protection devices.
Piccinini, Filippo; Balassa, Tamas; Szkalisity, Abel; Molnar, Csaba; Paavolainen, Lassi; Kujala, Kaisa; Buzas, Krisztina; Sarazova, Marie; Pietiainen, Vilja; Kutay, Ulrike; Smith, Kevin; Horvath, Peter
2017-06-28
High-content, imaging-based screens now routinely generate data on a scale that precludes manual verification and interrogation. Software applying machine learning has become an essential tool to automate analysis, but these methods require annotated examples to learn from. Efficiently exploring large datasets to find relevant examples remains a challenging bottleneck. Here, we present Advanced Cell Classifier (ACC), a graphical software package for phenotypic analysis that addresses these difficulties. ACC applies machine-learning and image-analysis methods to high-content data generated by large-scale, cell-based experiments. It features methods to mine microscopic image data, discover new phenotypes, and improve recognition performance. We demonstrate that these features substantially expedite the training process, successfully uncover rare phenotypes, and improve the accuracy of the analysis. ACC is extensively documented, designed to be user-friendly for researchers without machine-learning expertise, and distributed as a free open-source tool at www.cellclassifier.org. Copyright © 2017 Elsevier Inc. All rights reserved.
Detection of Cutting Tool Wear using Statistical Analysis and Regression Model
NASA Astrophysics Data System (ADS)
Ghani, Jaharah A.; Rizal, Muhammad; Nuawi, Mohd Zaki; Haron, Che Hassan Che; Ramli, Rizauddin
2010-10-01
This study presents a new method for detecting the cutting tool wear based on the measured cutting force signals. A statistical-based method called Integrated Kurtosis-based Algorithm for Z-Filter technique, called I-kaz was used for developing a regression model and 3D graphic presentation of I-kaz 3D coefficient during machining process. The machining tests were carried out using a CNC turning machine Colchester Master Tornado T4 in dry cutting condition. A Kistler 9255B dynamometer was used to measure the cutting force signals, which were transmitted, analyzed, and displayed in the DasyLab software. Various force signals from machining operation were analyzed, and each has its own I-kaz 3D coefficient. This coefficient was examined and its relationship with flank wear lands (VB) was determined. A regression model was developed due to this relationship, and results of the regression model shows that the I-kaz 3D coefficient value decreases as tool wear increases. The result then is used for real time tool wear monitoring.
Variability in the skin exposure of machine operators exposed to cutting fluids.
Wassenius, O; Järvholm, B; Engström, T; Lillienberg, L; Meding, B
1998-04-01
This study describes a new technique for measuring skin exposure to cutting fluids and evaluates the variability of skin exposure among machine operators performing cyclic (repetitive) work. The technique is based on video recording and subsequent analysis of the video tape by means of computer-synchronized video equipment. The time intervals at which the machine operator's hand was exposed to fluid were registered, and the total wet time of the skin was calculated by assuming different evaporation times for the fluid. The exposure of 12 operators with different work methods was analyzed in 6 different workshops, which included a range of machine types, from highly automated metal cutting machines (ie, actual cutting and chip removal machines) requiring operator supervision to conventional metal cutting machines, where the operator was required to maneuver the machine and manually exchange products. The relative wet time varied between 0% and 100%. A significant association between short cycle time and high relative wet time was noted. However, there was no relationship between the degree of automatization of the metal cutting machines and wet time. The study shows that skin exposure to cutting fluids can vary considerably between machine operators involved in manufacturing processes using different types of metal cutting machines. The machine type was not associated with dermal wetness. The technique appears to give objective information about dermal wetness.
Ozcift, Akin; Gulten, Arif
2011-12-01
Improving accuracies of machine learning algorithms is vital in designing high performance computer-aided diagnosis (CADx) systems. Researches have shown that a base classifier performance might be enhanced by ensemble classification strategies. In this study, we construct rotation forest (RF) ensemble classifiers of 30 machine learning algorithms to evaluate their classification performances using Parkinson's, diabetes and heart diseases from literature. While making experiments, first the feature dimension of three datasets is reduced using correlation based feature selection (CFS) algorithm. Second, classification performances of 30 machine learning algorithms are calculated for three datasets. Third, 30 classifier ensembles are constructed based on RF algorithm to assess performances of respective classifiers with the same disease data. All the experiments are carried out with leave-one-out validation strategy and the performances of the 60 algorithms are evaluated using three metrics; classification accuracy (ACC), kappa error (KE) and area under the receiver operating characteristic (ROC) curve (AUC). Base classifiers succeeded 72.15%, 77.52% and 84.43% average accuracies for diabetes, heart and Parkinson's datasets, respectively. As for RF classifier ensembles, they produced average accuracies of 74.47%, 80.49% and 87.13% for respective diseases. RF, a newly proposed classifier ensemble algorithm, might be used to improve accuracy of miscellaneous machine learning algorithms to design advanced CADx systems. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.
ERIC Educational Resources Information Center
Texas State Technical Coll., Waco.
This document is intended to help education and training institutions deliver the Machine Tool Advanced Skills Technology (MAST) curriculum to a variety of individuals and organizations. MAST consists of industry-specific skill standards and model curricula for 15 occupational specialty areas within the U.S. machine tool and metals-related…
ERIC Educational Resources Information Center
Texas State Technical Coll., Waco.
This document is intended to help education and training institutions deliver the Machine Tool Advanced Skills Technology (MAST) curriculum to a variety of individuals and organizations. MAST consists of industry-specific skill standards and model curricula for 15 occupational specialty areas within the U.S. machine tool and metals-related…
NASA Technical Reports Server (NTRS)
Malone, T. B.; Micocci, A.
1975-01-01
The alternate methods of conducting a man-machine interface evaluation are classified as static and dynamic, and are evaluated. A dynamic evaluation tool is presented to provide for a determination of the effectiveness of the man-machine interface in terms of the sequence of operations (task and task sequences) and in terms of the physical characteristics of the interface. This dynamic checklist approach is recommended for shuttle and shuttle payload man-machine interface evaluations based on reduced preparation time, reduced data, and increased sensitivity of critical problems.
ERIC Educational Resources Information Center
Texas State Technical Coll., Waco.
This document is intended to help education and training institutions deliver the Machine Tool Advanced Skills Technology (MAST) curriculum to a variety of individuals and organizations. MAST consists of industry-specific skill standards and model curricula for 15 occupational specialty areas within the U.S. machine tool and metals-related…
Machine learning for medical images analysis.
Criminisi, A
2016-10-01
This article discusses the application of machine learning for the analysis of medical images. Specifically: (i) We show how a special type of learning models can be thought of as automatically optimized, hierarchically-structured, rule-based algorithms, and (ii) We discuss how the issue of collecting large labelled datasets applies to both conventional algorithms as well as machine learning techniques. The size of the training database is a function of model complexity rather than a characteristic of machine learning methods. Crown Copyright © 2016. Published by Elsevier B.V. All rights reserved.
ERIC Educational Resources Information Center
Texas State Technical Coll., Waco.
This document is intended to help education and training institutions deliver the Machine Tool Advanced Skills Technology (MAST) curriculum to a variety of individuals and organizations. MAST consists of industry-specific skill standards and model curricula for 15 occupational specialty areas within the U.S. machine tool and metals-related…
ERIC Educational Resources Information Center
Texas State Technical Coll., Waco.
This document is intended to help education and training institutions deliver the Machine Tool Advanced Skills Technology (MAST) curriculum to a variety of individuals and organizations. MAST consists of industry-specific skill standards and model curricula for 15 occupational specialty areas within the U.S. machine tool and metals-related…
ERIC Educational Resources Information Center
Texas State Technical Coll., Waco.
This document is intended to help education and training institutions deliver the Machine Tool Advanced Skills Technology (MAST) curriculum to a variety of individuals and organizations. MAST consists of industry-specific skill standards and model curricula for 15 occupational specialty areas within the U.S. machine tool and metals-related…
ERIC Educational Resources Information Center
Texas State Technical Coll., Waco.
This document is intended to help education and training institutions deliver the Machine Tool Advanced Skills Technology (MAST) curriculum to a variety of individuals and organizations. MAST consists of industry-specific skill standards and model curricula for 15 occupational specialty areas within the U.S. machine tool and metals-related…
ERIC Educational Resources Information Center
Texas State Technical Coll., Waco.
This document is intended to help education and training institutions deliver the Machine Tool Advanced Skills Technology (MAST) curriculum to a variety of individuals and organizations. MAST consists of industry-specific skill standards and model curricula for 15 occupational specialty areas within the U.S. machine tool and metals-related…
Phenolic cutter for machining foam insulation
NASA Technical Reports Server (NTRS)
Blair, T. A.; Miller, A. C.; Price, B. W.; Stiles, W. S.
1970-01-01
Pre-pregged fiber glass is an efficient abrasive for machining polystyrene and polyurethane foams. It bonds easily to any cutter base made of aluminum, steel, or phenolic, is inexpensive, and is readily available.
Quantification of uncertainty in machining operations for on-machine acceptance.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Claudet, Andre A.; Tran, Hy D.; Su, Jiann-Chemg
2008-09-01
Manufactured parts are designed with acceptance tolerances, i.e. deviations from ideal design conditions, due to unavoidable errors in the manufacturing process. It is necessary to measure and evaluate the manufactured part, compared to the nominal design, to determine whether the part meets design specifications. The scope of this research project is dimensional acceptance of machined parts; specifically, parts machined using numerically controlled (NC, or also CNC for Computer Numerically Controlled) machines. In the design/build/accept cycle, the designer will specify both a nominal value, and an acceptable tolerance. As part of the typical design/build/accept business practice, it is required to verifymore » that the part did meet acceptable values prior to acceptance. Manufacturing cost must include not only raw materials and added labor, but also the cost of ensuring conformance to specifications. Ensuring conformance is a substantial portion of the cost of manufacturing. In this project, the costs of measurements were approximately 50% of the cost of the machined part. In production, cost of measurement would be smaller, but still a substantial proportion of manufacturing cost. The results of this research project will point to a science-based approach to reducing the cost of ensuring conformance to specifications. The approach that we take is to determine, a priori, how well a CNC machine can manufacture a particular geometry from stock. Based on the knowledge of the manufacturing process, we are then able to decide features which need further measurements from features which can be accepted 'as is' from the CNC. By calibration of the machine tool, and establishing a machining accuracy ratio, we can validate the ability of CNC to fabricate to a particular level of tolerance. This will eliminate the costs of checking for conformance for relatively large tolerances.« less
Machine learning in cardiovascular medicine: are we there yet?
Shameer, Khader; Johnson, Kipp W; Glicksberg, Benjamin S; Dudley, Joel T; Sengupta, Partho P
2018-01-19
Artificial intelligence (AI) broadly refers to analytical algorithms that iteratively learn from data, allowing computers to find hidden insights without being explicitly programmed where to look. These include a family of operations encompassing several terms like machine learning, cognitive learning, deep learning and reinforcement learning-based methods that can be used to integrate and interpret complex biomedical and healthcare data in scenarios where traditional statistical methods may not be able to perform. In this review article, we discuss the basics of machine learning algorithms and what potential data sources exist; evaluate the need for machine learning; and examine the potential limitations and challenges of implementing machine in the context of cardiovascular medicine. The most promising avenues for AI in medicine are the development of automated risk prediction algorithms which can be used to guide clinical care; use of unsupervised learning techniques to more precisely phenotype complex disease; and the implementation of reinforcement learning algorithms to intelligently augment healthcare providers. The utility of a machine learning-based predictive model will depend on factors including data heterogeneity, data depth, data breadth, nature of modelling task, choice of machine learning and feature selection algorithms, and orthogonal evidence. A critical understanding of the strength and limitations of various methods and tasks amenable to machine learning is vital. By leveraging the growing corpus of big data in medicine, we detail pathways by which machine learning may facilitate optimal development of patient-specific models for improving diagnoses, intervention and outcome in cardiovascular medicine. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
NASA Astrophysics Data System (ADS)
Zheng, Yuanliao; Chen, Pingping; Ding, Jiayi; Yang, Heming; Nie, Xiaofei; Zhou, Xiaohao; Chen, Xiaoshuang; Lu, Wei
2018-06-01
A hybrid structure consisting of periodic gold stripes and an overlaying gold film has been proposed as the optical coupler of a long-wave quantum well infrared photodetector. Absorption spectra and field distributions of the structure at back-side normal incidence are calculated by the finite difference time-domain method. The results indicate that the intersubband absorption can be greatly enhanced based on the waveguide resonance as well as the surface plasmon polariton (SPP) mode. With the optimized structural parameters of the periodic gold stripes, the maximal intersubband absorption can exceed 80%, which is much higher than the SPP-enhanced intersubband absorption (<50%) and about 6 times the one of the standard device. The relationship between the structural parameters and the waveguide resonant wavelength is derived. Other advantages of the efficient optical coupling based on waveguide resonance are also discussed.
Differential absorption lidar measurements of atmospheric temperature and pressure profiles
NASA Technical Reports Server (NTRS)
Korb, C. L.
1981-01-01
The theory and methodology of using differential absorption lidar techniques for the remote measurement of atmospheric pressure profiles, surface pressure, and temperature profiles from ground, air, and space-based platforms are presented. Pressure measurements are effected by means of high resolution measurement of absorption at the edges of the oxygen A band lines where absorption is pressure dependent due to collisional line broadening. Temperature is assessed using measurements of the absorption at the center of the oxygen A band line originating from a quantum state with high ground state energy. The population of the state is temperature dependent, allowing determination of the temperature through the Boltzmann term. The results of simulations of the techniques using Voigt profile and variational analysis are reported for ground-based, airborne, and Shuttle-based systems. Accuracies in the 0.5-1.0 K and 0.1-0.3% range are projected.
Context-sensitive trace inlining for Java.
Häubl, Christian; Wimmer, Christian; Mössenböck, Hanspeter
2013-12-01
Method inlining is one of the most important optimizations in method-based just-in-time (JIT) compilers. It widens the compilation scope and therefore allows optimizing multiple methods as a whole, which increases the performance. However, if method inlining is used too frequently, the compilation time increases and too much machine code is generated. This has negative effects on the performance. Trace-based JIT compilers only compile frequently executed paths, so-called traces, instead of whole methods. This may result in faster compilation, less generated machine code, and better optimized machine code. In the previous work, we implemented a trace recording infrastructure and a trace-based compiler for [Formula: see text], by modifying the Java HotSpot VM. Based on this work, we evaluate the effect of trace inlining on the performance and the amount of generated machine code. Trace inlining has several major advantages when compared to method inlining. First, trace inlining is more selective than method inlining, because only frequently executed paths are inlined. Second, the recorded traces may capture information about virtual calls, which simplify inlining. A third advantage is that trace information is context sensitive so that different method parts can be inlined depending on the specific call site. These advantages allow more aggressive inlining while the amount of generated machine code is still reasonable. We evaluate several inlining heuristics on the benchmark suites DaCapo 9.12 Bach, SPECjbb2005, and SPECjvm2008 and show that our trace-based compiler achieves an up to 51% higher peak performance than the method-based Java HotSpot client compiler. Furthermore, we show that the large compilation scope of our trace-based compiler has a positive effect on other compiler optimizations such as constant folding or null check elimination.
Critical Speed of The Glass Glue Machine's Creep and Influence Factors Analysis
NASA Astrophysics Data System (ADS)
Yang, Jianxi; Huang, Jian; Wang, Liying; Shi, Jintai
When automatic glass glue machine works, two questions of the machine starting vibrating and stick-slip motion are existing. These problems should be solved. According to these questions, a glue machine's model for studying stick-slip is established. Based on the dynamics system describing of the model, mathematical expression is presented. The creep critical speed expression is constructed referring to existing research achievement and a new conclusion is found. The influencing factors of stiffness, dampness, mass, velocity, difference of static and kinetic coefficient of friction are analyzed through Matlab simulation. Research shows that reasonable choice of influence parameters can improve the creep phenomenon. These all supply the theory evidence for improving the machine's motion stability.
Prostate Cancer Probability Prediction By Machine Learning Technique.
Jović, Srđan; Miljković, Milica; Ivanović, Miljan; Šaranović, Milena; Arsić, Milena
2017-11-26
The main goal of the study was to explore possibility of prostate cancer prediction by machine learning techniques. In order to improve the survival probability of the prostate cancer patients it is essential to make suitable prediction models of the prostate cancer. If one make relevant prediction of the prostate cancer it is easy to create suitable treatment based on the prediction results. Machine learning techniques are the most common techniques for the creation of the predictive models. Therefore in this study several machine techniques were applied and compared. The obtained results were analyzed and discussed. It was concluded that the machine learning techniques could be used for the relevant prediction of prostate cancer.
NASA Astrophysics Data System (ADS)
Lee, Donghoon; Kim, Ye-seul; Choi, Sunghoon; Lee, Haenghwa; Jo, Byungdu; Choi, Seungyeon; Shin, Jungwook; Kim, Hee-Joung
2017-03-01
The chest digital tomosynthesis(CDT) is recently developed medical device that has several advantage for diagnosing lung disease. For example, CDT provides depth information with relatively low radiation dose compared to computed tomography (CT). However, a major problem with CDT is the image artifacts associated with data incompleteness resulting from limited angle data acquisition in CDT geometry. For this reason, the sensitivity of lung disease was not clear compared to CT. In this study, to improve sensitivity of lung disease detection in CDT, we developed computer aided diagnosis (CAD) systems based on machine learning. For design CAD systems, we used 100 cases of lung nodules cropped images and 100 cases of normal lesion cropped images acquired by lung man phantoms and proto type CDT. We used machine learning techniques based on support vector machine and Gabor filter. The Gabor filter was used for extracting characteristics of lung nodules and we compared performance of feature extraction of Gabor filter with various scale and orientation parameters. We used 3, 4, 5 scales and 4, 6, 8 orientations. After extracting features, support vector machine (SVM) was used for classifying feature of lesions. The linear, polynomial and Gaussian kernels of SVM were compared to decide the best SVM conditions for CDT reconstruction images. The results of CAD system with machine learning showed the capability of automatically lung lesion detection. Furthermore detection performance was the best when Gabor filter with 5 scale and 8 orientation and SVM with Gaussian kernel were used. In conclusion, our suggested CAD system showed improving sensitivity of lung lesion detection in CDT and decide Gabor filter and SVM conditions to achieve higher detection performance of our developed CAD system for CDT.
Generation of gear tooth surfaces by application of CNC machines
NASA Technical Reports Server (NTRS)
Litvin, F. L.; Chen, N. X.
1994-01-01
This study will demonstrate the importance of application of computer numerically controlled (CNC) machines in generation of gear tooth surfaces with new topology. This topology decreases gear vibration and will extend the gear capacity and service life. A preliminary investigation by a tooth contact analysis (TCA) program has shown that gear tooth surfaces in line contact (for instance, involute helical gears with parallel axes, worm gear drives with cylindrical worms, etc.) are very sensitive to angular errors of misalignment that cause edge contact and an unfavorable shape of transmission errors and vibration. The new topology of gear tooth surfaces is based on the localization of bearing contact, and the synthesis of a predesigned parabolic function of transmission errors that is able to absorb a piecewise linear function of transmission errors caused by gear misalignment. The report will describe the following topics: description of kinematics of CNC machines with six degrees of freedom that can be applied for generation of gear tooth surfaces with new topology. A new method for grinding of gear tooth surfaces by a cone surface or surface of revolution based on application of CNC machines is described. This method provides an optimal approximation of the ground surface to the given one. This method is especially beneficial when undeveloped ruled surfaces are to be ground. Execution of motions of the CNC machine is also described. The solution to this problem can be applied as well for the transfer of machine tool settings from a conventional generator to the CNC machine. The developed theory required the derivation of a modified equation of meshing based on application of the concept of space curves, space curves represented on surfaces, geodesic curvature, surface torsion, etc. Condensed information on these topics of differential geometry is provided as well.
NASA Astrophysics Data System (ADS)
Chen, Hua; Chen, Jihong; Wang, Baorui; Zheng, Yongcheng
2016-10-01
The Magnetorheological finishing (MRF) process, based on the dwell time method with the constant normal spacing for flexible polishing, would bring out the normal contour error in the fine polishing complex surface such as aspheric surface. The normal contour error would change the ribbon's shape and removal characteristics of consistency for MRF. Based on continuously scanning the normal spacing between the workpiece and the finder by the laser range finder, the novel method was put forward to measure the normal contour errors while polishing complex surface on the machining track. The normal contour errors was measured dynamically, by which the workpiece's clamping precision, multi-axis machining NC program and the dynamic performance of the MRF machine were achieved for the verification and security check of the MRF process. The unit for measuring the normal contour errors of complex surface on-machine was designed. Based on the measurement unit's results as feedback to adjust the parameters of the feed forward control and the multi-axis machining, the optimized servo control method was presented to compensate the normal contour errors. The experiment for polishing 180mm × 180mm aspherical workpiece of fused silica by MRF was set up to validate the method. The results show that the normal contour error was controlled in less than 10um. And the PV value of the polished surface accuracy was improved from 0.95λ to 0.09λ under the conditions of the same process parameters. The technology in the paper has been being applied in the PKC600-Q1 MRF machine developed by the China Academe of Engineering Physics for engineering application since 2014. It is being used in the national huge optical engineering for processing the ultra-precision optical parts.
Interpreting linear support vector machine models with heat map molecule coloring
2011-01-01
Background Model-based virtual screening plays an important role in the early drug discovery stage. The outcomes of high-throughput screenings are a valuable source for machine learning algorithms to infer such models. Besides a strong performance, the interpretability of a machine learning model is a desired property to guide the optimization of a compound in later drug discovery stages. Linear support vector machines showed to have a convincing performance on large-scale data sets. The goal of this study is to present a heat map molecule coloring technique to interpret linear support vector machine models. Based on the weights of a linear model, the visualization approach colors each atom and bond of a compound according to its importance for activity. Results We evaluated our approach on a toxicity data set, a chromosome aberration data set, and the maximum unbiased validation data sets. The experiments show that our method sensibly visualizes structure-property and structure-activity relationships of a linear support vector machine model. The coloring of ligands in the binding pocket of several crystal structures of a maximum unbiased validation data set target indicates that our approach assists to determine the correct ligand orientation in the binding pocket. Additionally, the heat map coloring enables the identification of substructures important for the binding of an inhibitor. Conclusions In combination with heat map coloring, linear support vector machine models can help to guide the modification of a compound in later stages of drug discovery. Particularly substructures identified as important by our method might be a starting point for optimization of a lead compound. The heat map coloring should be considered as complementary to structure based modeling approaches. As such, it helps to get a better understanding of the binding mode of an inhibitor. PMID:21439031
NASA Astrophysics Data System (ADS)
Vu, Duy-Duc; Monies, Frédéric; Rubio, Walter
2018-05-01
A large number of studies, based on 3-axis end milling of free-form surfaces, seek to optimize tool path planning. Approaches try to optimize the machining time by reducing the total tool path length while respecting the criterion of the maximum scallop height. Theoretically, the tool path trajectories that remove the most material follow the directions in which the machined width is the largest. The free-form surface is often considered as a single machining area. Therefore, the optimization on the entire surface is limited. Indeed, it is difficult to define tool trajectories with optimal feed directions which generate largest machined widths. Another limiting point of previous approaches for effectively reduce machining time is the inadequate choice of the tool. Researchers use generally a spherical tool on the entire surface. However, the gains proposed by these different methods developed with these tools lead to relatively small time savings. Therefore, this study proposes a new method, using toroidal milling tools, for generating toolpaths in different regions on the machining surface. The surface is divided into several regions based on machining intervals. These intervals ensure that the effective radius of the tool, at each cutter-contact points on the surface, is always greater than the radius of the tool in an optimized feed direction. A parallel plane strategy is then used on the sub-surfaces with an optimal specific feed direction for each sub-surface. This method allows one to mill the entire surface with efficiency greater than with the use of a spherical tool. The proposed method is calculated and modeled using Maple software to find optimal regions and feed directions in each region. This new method is tested on a free-form surface. A comparison is made with a spherical cutter to show the significant gains obtained with a toroidal milling cutter. Comparisons with CAM software and experimental validations are also done. The results show the efficiency of the method.
DOE Office of Scientific and Technical Information (OSTI.GOV)
None
This factsheet describes a project that developed and demonstrated a new manufacturing-informed design framework that utilizes advanced multi-scale, physics-based process modeling to dramatically improve manufacturing productivity and quality in machining operations while reducing the cost of machined components.
14. Machine room, building 501, underground structure, May 11, 1956, ...
14. Machine room, building 501, underground structure, May 11, 1956, looking east - Offutt Air Force Base, Strategic Air Command Headquarters & Command Center, Command Center, 901 SAC Boulevard, Bellevue, Sarpy County, NE
Hospital-acquired listeriosis linked to a persistently contaminated milkshake machine.
Mazengia, E; Kawakami, V; Rietberg, K; Kay, M; Wyman, P; Skilton, C; Aberra, A; Boonyaratanakornkit, J; Limaye, A P; Pergam, S A; Whimbey, E; Olsen-Scribner, R J; Duchin, J S
2017-04-01
One case of hospital-acquired listeriosis was linked to milkshakes produced in a commercial-grade shake freezer machine. This machine was found to be contaminated with a strain of Listeria monocytogenes epidemiologically and molecularly linked to a contaminated pasteurized, dairy-based ice cream product at the same hospital a year earlier, despite repeated cleaning and sanitizing. Healthcare facilities should be aware of the potential for prolonged Listeria contamination of food service equipment. In addition, healthcare providers should consider counselling persons who have an increased risk for Listeria infections regarding foods that have caused Listeria infections. The prevalence of persistent Listeria contamination of commercial-grade milkshake machines in healthcare facilities and the risk associated with serving dairy-based ice cream products to hospitalized patients at increased risk for invasive L. monocytogenes infections should be further evaluated.
NASA Astrophysics Data System (ADS)
Gagliardi, Francesco
In the present paper we discuss some aspects of the development of categorization theories concerning cognitive psychology and machine learning. We consider the thirty-year debate between prototype-theory and exemplar-theory in the studies of cognitive psychology regarding the categorization processes. We propose this debate is ill-posed, because it neglects some theoretical and empirical results of machine learning about the bias-variance theorem and the existence of some instance-based classifiers which can embed models subsuming both prototype and exemplar theories. Moreover this debate lies on a epistemological error of pursuing a, so called, experimentum crucis. Then we present how an interdisciplinary approach, based on synthetic method for cognitive modelling, can be useful to progress both the fields of cognitive psychology and machine learning.
An implementation of support vector machine on sentiment classification of movie reviews
NASA Astrophysics Data System (ADS)
Yulietha, I. M.; Faraby, S. A.; Adiwijaya; Widyaningtyas, W. C.
2018-03-01
With technological advances, all information about movie is available on the internet. If the information is processed properly, it will get the quality of the information. This research proposes to the classify sentiments on movie review documents. This research uses Support Vector Machine (SVM) method because it can classify high dimensional data in accordance with the data used in this research in the form of text. Support Vector Machine is a popular machine learning technique for text classification because it can classify by learning from a collection of documents that have been classified previously and can provide good result. Based on number of datasets, the 90-10 composition has the best result that is 85.6%. Based on SVM kernel, kernel linear with constant 1 has the best result that is 84.9%
The Design of Finite State Machine for Asynchronous Replication Protocol
NASA Astrophysics Data System (ADS)
Wang, Yanlong; Li, Zhanhuai; Lin, Wei; Hei, Minglei; Hao, Jianhua
Data replication is a key way to design a disaster tolerance system and to achieve reliability and availability. It is difficult for a replication protocol to deal with the diverse and complex environment. This means that data is less well replicated than it ought to be. To reduce data loss and to optimize replication protocols, we (1) present a finite state machine, (2) run it to manage an asynchronous replication protocol and (3) report a simple evaluation of the asynchronous replication protocol based on our state machine. It's proved that our state machine is applicable to guarantee the asynchronous replication protocol running in the proper state to the largest extent in the event of various possible events. It also can helpful to build up replication-based disaster tolerance systems to ensure the business continuity.
Methodology for creating dedicated machine and algorithm on sunflower counting
NASA Astrophysics Data System (ADS)
Muracciole, Vincent; Plainchault, Patrick; Mannino, Maria-Rosaria; Bertrand, Dominique; Vigouroux, Bertrand
2007-09-01
In order to sell grain lots in European countries, seed industries need a government certification. This certification requests purity testing, seed counting in order to quantify specified seed species and other impurities in lots, and germination testing. These analyses are carried out within the framework of international trade according to the methods of the International Seed Testing Association. Presently these different analyses are still achieved manually by skilled operators. Previous works have already shown that seeds can be characterized by around 110 visual features (morphology, colour, texture), and thus have presented several identification algorithms. Until now, most of the works in this domain are computer based. The approach presented in this article is based on the design of dedicated electronic vision machine aimed to identify and sort seeds. This machine is composed of a FPGA (Field Programmable Gate Array), a DSP (Digital Signal Processor) and a PC bearing the GUI (Human Machine Interface) of the system. Its operation relies on the stroboscopic image acquisition of a seed falling in front of a camera. A first machine was designed according to this approach, in order to simulate all the vision chain (image acquisition, feature extraction, identification) under the Matlab environment. In order to perform this task into dedicated hardware, all these algorithms were developed without the use of the Matlab toolbox. The objective of this article is to present a design methodology for a special purpose identification algorithm based on distance between groups into dedicated hardware machine for seed counting.
Tunable multi-band absorption in metasurface of graphene ribbons based on composite structure
NASA Astrophysics Data System (ADS)
Ning, Renxia; Jiao, Zheng; Bao, Jie
2017-05-01
A tunable multiband absorption based on a graphene metasurface of composite structure at mid-infrared frequency was investigated by the finite difference time domain method. The composite structure were composed of graphene ribbons and a gold-MgF2 layer which was sandwiched in between two dielectric slabs. The permittivity of graphene is discussed with different chemical potential to obtain tunable absorption. And the absorption of the composite structure can be tuned by the chemical potential of graphene at certain frequencies. The impedance matching was used to study the perfect absorption of the structure in our paper. The results show that multi-band absorption can be obtained and some absorption peaks of the composite structure can be tuned through the changing not only of the width of graphene ribbons and gaps, but also the dielectric and the chemical potential of graphene. However, another peak was hardly changed by parameters due to a different resonant mechanism in proposed structure. This flexibily tunable multiband absorption may be applied to optical communications such as optical absorbers, mid infrared stealth devices and filters.
NASA Astrophysics Data System (ADS)
Schierz, Amanda C.; King, Ross D.
Compounds in drug screening-libraries should resemble pharmaceuticals. To operationally test this, we analysed the compounds in terms of known drug-like filters and developed a novel machine learning method to discriminate approved pharmaceuticals from “drug-like” compounds. This method uses both structural features and molecular properties for discrimination. The method has an estimated accuracy of 91% in discriminating between the Maybridge HitFinder library and approved pharmaceuticals, and 99% between the NATDiverse collection (from Analyticon Discovery) and approved pharmaceuticals. These results show that Lipinski’s Rule of 5 for oral absorption is not sufficient to describe “drug-likeness” and be the main basis of screening-library design.
Web-Based Machine Translation as a Tool for Promoting Electronic Literacy and Language Awareness
ERIC Educational Resources Information Center
Williams, Lawrence
2006-01-01
This article addresses a pervasive problem of concern to teachers of many foreign languages: the use of Web-Based Machine Translation (WBMT) by students who do not understand the complexities of this relatively new tool. Although networked technologies have greatly increased access to many language and communication tools, WBMT is still…
The Value Simulation-Based Learning Added to Machining Technology in Singapore
ERIC Educational Resources Information Center
Fang, Linda; Tan, Hock Soon; Thwin, Mya Mya; Tan, Kim Cheng; Koh, Caroline
2011-01-01
This study seeks to understand the value simulation-based learning (SBL) added to the learning of Machining Technology in a 15-week core subject course offered to university students. The research questions were: (1) How did SBL enhance classroom learning? (2) How did SBL help participants in their test? (3) How did SBL prepare participants for…