Science.gov

Sample records for abstracts initially identified

  1. Towards Identify Selective Antibacterial Peptides Based on Abstracts Meaning

    PubMed Central

    Barbosa-Santillán, Liliana I.; Sánchez-Escobar, Juan J.; Calixto-Romo, M. Angeles; Barbosa-Santillán, Luis F.

    2016-01-01

    We present an Identify Selective Antibacterial Peptides (ISAP) approach based on abstracts meaning. Laboratories and researchers have significantly increased the report of their discoveries related to antibacterial peptides in primary publications. It is important to find antibacterial peptides that have been reported in primary publications because they can produce antibiotics of different generations that attack and destroy the bacteria. Unfortunately, researchers used heterogeneous forms of natural language to describe their discoveries (sometimes without the sequence of the peptides). Thus, we propose that learning the words meaning instead of the antibacterial peptides sequence is possible to identify and predict antibacterial peptides reported in the PubMed engine. The ISAP approach consists of two stages: training and discovering. ISAP founds that the 35% of the abstracts sample had antibacterial peptides and we tested in the updated Antimicrobial Peptide Database 2 (APD2). ISAP predicted that 45% of the abstracts had antibacterial peptides. That is, ISAP found that 810 antibacterial peptides were not classified like that, so they are not reported in APD2. As a result, this new search tool would complement the APD2 with a set of peptides that are candidates to be antibacterial. Finally, 20% of the abstracts were not semantic related to APD2. PMID:27366202

  2. Identifying SRD Variables Among "Miscellaneous" ASAS Stars (Poster abstract)

    NASA Astrophysics Data System (ADS)

    Quinonez, M.; Larsen, K.

    2016-06-01

    (Abstract only) The International Variable Star Index (VSX) contains a large number of stars observed and analyzed by the All Sky Automated Survey (ASAS). While ASAS is a powerful tool in terms of the sheer volume of data it collects, its automated light curve analysis is not always robust enough to reliably identify stars that are not strictly regular in their magnitude variations. As a consequence, it was suspected that potentially many variable stars of the semiregular type were instead added to the VSX under a miscellaneous (MISC) classification. A subset of these semiregular stars, known as SRD variables, has a well-defined set of parameters regarding their classification - they are of the F, G, or K spectral type, their amplitudes of light variation are between 0.1 and 4 magnitudes, and their periods of variation can span 30 to 1,100 days. Furthermore, SRD variables are giants or supergiants, and therefore typically distant with small proper motions. A search was made through stars listed as MISC in the VSX using the above parameters, as well detailed light curve analyses via the AAVSO's VStar program, in order to find ASAS SRDs that were misclassified as MISC. This study of 90 stars has yielded five new SRDs to date. In addition, some data pertaining to several stars that were not confirmed to be of the SRD type were found to contain errors, and have since been revised accordingly in VSX.

  3. Abstracts

    ERIC Educational Resources Information Center

    American Biology Teacher, 1977

    1977-01-01

    Included are over 50 abstracts of papers being presented at the 1977 National Association of Biology Teachers Convention. Included in each abstract are the title, author, and summary of the paper. Topics include photographic techniques environmental studies, and biological instruction. (MA)

  4. Field Initiated Studies Program. Abstracts of Funded Projects 1992.

    ERIC Educational Resources Information Center

    Office of Educational Research and Improvement (ED), Washington, DC. Office of Research.

    The Field-Initiated Studies program is open to institutions of higher education, public and private organizations, institutions, and agencies, as well as individuals. Applicants may propose projects that last up to 18 months, and proposals are reviewed and evaluated based on their technical quality and national importance judged by scholars and…

  5. Possibilities of identifying cyber attack in noisy space of n-dimensional abstract system

    NASA Astrophysics Data System (ADS)

    Jašek, Roman; Dvořák, Jiří; Janková, Martina; Sedláček, Michal

    2016-06-01

    This article briefly mentions some selected options of current concept for identifying cyber attacks from the perspective of the new cyberspace of real system. In the cyberspace, there is defined n-dimensional abstract system containing elements of the spatial arrangement of partial system elements such as micro-environment of cyber systems surrounded by other suitably arranged corresponding noise space. This space is also gradually supplemented by a new image of dynamic processes in a discreet environment, and corresponding again to n-dimensional expression of time space defining existence and also the prediction for expected cyber attacksin the noise space. Noises are seen here as useful and necessary for modern information and communication technologies (e.g. in processes of applied cryptography in ICT) and then the so-called useless noises designed for initial (necessary) filtering of this highly aggressive environment and in future expectedly offensive background in cyber war (e.g. the destruction of unmanned means of an electromagnetic pulse, or for destruction of new safety barriers created on principles of electrostatic field or on other principles of modern physics, etc.). The key to these new options is the expression of abstract systems based on the models of microelements of cyber systems and their hierarchical concept in structure of n-dimensional system in given cyberspace. The aim of this article is to highlight the possible systemic expression of cyberspace of abstract system and possible identification in time-spatial expression of real environment (on microelements of cyber systems and their surroundings with noise characteristics and time dimension in dynamic of microelements' own time and externaltime defined by real environment). The article was based on a partial task of faculty specific research.

  6. Identifying crop vulnerability to groundwater abstraction: modelling and expert knowledge in a GIS.

    PubMed

    Procter, Chris; Comber, Lex; Betson, Mark; Buckley, Dennis; Frost, Andy; Lyons, Hester; Riding, Alison; Voyce, Kevin

    2006-11-01

    Water use is expected to increase and climate change scenarios indicate the need for more frequent water abstraction. Abstracting groundwater may have a detrimental effect on soil moisture availability for crop growth and yields. This work presents an elegant and robust method for identifying zones of crop vulnerability to abstraction. Archive groundwater level datasets were used to generate a composite groundwater surface that was subtracted from a digital terrain model. The result was the depth from surface to groundwater and identified areas underlain by shallow groundwater. Knowledge from an expert agronomist was used to define classes of risk in terms of their depth below ground level. Combining information on the permeability of geological drift types further refined the assessment of the risk of crop growth vulnerability. The nature of the mapped output is one that is easy to communicate to the intended farming audience because of the general familiarity of mapped information. Such Geographic Information System (GIS)-based products can play a significant role in the characterisation of catchments under the EU Water Framework Directive especially in the process of public liaison that is fundamental to the setting of priorities for management change. The creation of a baseline allows the impact of future increased water abstraction rates to be modelled and the vulnerability maps are in a format that can be readily understood by the various stakeholders. This methodology can readily be extended to encompass additional data layers and for a range of groundwater vulnerability issues including water resources, ecological impacts, nitrate and phosphorus.

  7. Deformylation Reaction by a Nonheme Manganese(III)-Peroxo Complex via Initial Hydrogen-Atom Abstraction.

    PubMed

    Barman, Prasenjit; Upadhyay, Pranav; Faponle, Abayomi S; Kumar, Jitendra; Nag, Sayanta Sekhar; Kumar, Devesh; Sastri, Chivukula V; de Visser, Sam P

    2016-09-05

    Metal-peroxo intermediates are key species in the catalytic cycles of nonheme metalloenzymes, but their chemical properties and reactivity patterns are still poorly understood. The synthesis and characterization of a manganese(III)-peroxo complex with a pentadentate bispidine ligand system and its reactivity with aldehydes was studied. Manganese(III)-peroxo can react through hydrogen-atom abstraction reactions instead of the commonly proposed nucleophilic addition reaction. Evidence of the mechanism comes from experiments which identify a primary kinetic isotope effect of 5.4 for the deformylation reaction. Computational modeling supports the established mechanism and identifies the origin of the reactivity preference of hydrogen-atom abstraction over nucleophilic addition.

  8. A micro focus with macro impact: Exploration of initial abstraction coefficient ratio (λ) in Soil Conservation Curve Number (CN) methodology

    NASA Astrophysics Data System (ADS)

    Ling, L.; Yusop, Z.

    2014-02-01

    Researchers started to cross examine United States Department of Agriculture (USDA) Soil Conservation Services (SCS) Curve Number (CN) methodology after the technique produced inconsistent results throughout the world. More field data from recent decades were leaning against the assumption of the initial abstraction coefficient ratio value proposed by SCS in 1954. Physiographic conditions were identified as vital influencing factors to be considered under this methodology while practitioners of this method are encouraged to validate and derive regional specific relationship and employ the method with caution.

  9. De-identifying a public use microdata file from the Canadian national discharge abstract database

    PubMed Central

    2011-01-01

    Abstract Background The Canadian Institute for Health Information (CIHI) collects hospital discharge abstract data (DAD) from Canadian provinces and territories. There are many demands for the disclosure of this data for research and analysis to inform policy making. To expedite the disclosure of data for some of these purposes, the construction of a DAD public use microdata file (PUMF) was considered. Such purposes include: confirming some published results, providing broader feedback to CIHI to improve data quality, training students and fellows, providing an easily accessible data set for researchers to prepare for analyses on the full DAD data set, and serve as a large health data set for computer scientists and statisticians to evaluate analysis and data mining techniques. The objective of this study was to measure the probability of re-identification for records in a PUMF, and to de-identify a national DAD PUMF consisting of 10% of records. Methods Plausible attacks on a PUMF were evaluated. Based on these attacks, the 2008-2009 national DAD was de-identified. A new algorithm was developed to minimize the amount of suppression while maximizing the precision of the data. The acceptable threshold for the probability of correct re-identification of a record was set at between 0.04 and 0.05. Information loss was measured in terms of the extent of suppression and entropy. Results Two different PUMF files were produced, one with geographic information, and one with no geographic information but more clinical information. At a threshold of 0.05, the maximum proportion of records with the diagnosis code suppressed was 20%, but these suppressions represented only 8-9% of all values in the DAD. Our suppression algorithm has less information loss than a more traditional approach to suppression. Smaller regions, patients with longer stays, and age groups that are infrequently admitted to hospitals tend to be the ones with the highest rates of suppression. Conclusions The

  10. The Quest for Identifying BY Draconis Stars within a Data Set of 3,548 Candidate Cepheid Variable Stars (Abstract)

    NASA Astrophysics Data System (ADS)

    Johnson, J.

    2016-06-01

    (Abstract only) A spreadsheet of 3,548 automatically classified candidate Cepheid variable stars from the ASAS (All Sky Automated Survey) photometry data was provided to AAVSO (American Association of Variable Star Observers) members for analysis. It was known that the computer filters had significantly overpopulated the list. Patrick Wils originally investigated a small subset of the data using 2MASS, PPMXL, and ROTSE data, and discovered that the vast majority of the 84 candidates he surveyed appeared to have been misidentified, demonstrating the need to reclassify these variables. The most common misidentification seemed to be of BY Draconis stars (K and M spotted dwarfs), which led to an ongoing project to systematically identify BY Draconis stars from this data set. The stars are sorted using the International Variable Star Index (VSX) information and ASAS light curves to search for prior reclassification by other authors in the time since the initial population of the candidate list (e.g. using ROTSE data), along with infrared photometry (2MASS) and proper motion (PPMXL) data. An analysis of light curves and phase plots using the AAVSO software vstar is the final step in identifying potential BY Draconis stars. The goal of this project has been to submit updated identifications for these stars to VSX. This final presentation on this project will identify the last set of reclassified BY Draconis stars and discuss future directions for this research.

  11. Novel approach for identifying key residues in enzymatic reactions: proton abstraction in ketosteroid isomerase.

    PubMed

    Ito, Mika; Brinck, Tore

    2014-11-20

    We propose a computationally efficient approach for evaluating the individual contributions of many different residues to the catalytic efficiency of an enzymatic reaction. This approach is based on the fragment molecular orbital (FMO) method, and it defines the energy of a deletion form, i.e., the energy of the system when a particular residue is deleted. Using this approach, we found that, among 10 investigated residues, three, Tyr14, Asp99, and Tyr55, in this order, significantly reduce the activation energy of the proton abstraction from a substrate, cyclopent-2-enone, catalyzed by ketosteroid isomerase (KSI). The relative activation energies estimated in this study are in good agreement with available previous experimental and theoretical data obtained for the similar proton abstraction with a native substrate and substitution mutants of KSI. It was thus indicated that the new approach is efficient for rationally evaluating the catalytic effects of multiple residues on an enzymatic reaction.

  12. An initial-abstraction, constant-loss model for unit hydrograph modeling for applicable watersheds in Texas

    USGS Publications Warehouse

    Asquith, William H.; Roussel, Meghan C.

    2007-01-01

    Estimation of representative hydrographs from design storms, which are known as design hydrographs, provides for cost-effective, riskmitigated design of drainage structures such as bridges, culverts, roadways, and other infrastructure. During 2001?07, the U.S. Geological Survey (USGS), in cooperation with the Texas Department of Transportation, investigated runoff hydrographs, design storms, unit hydrographs,and watershed-loss models to enhance design hydrograph estimation in Texas. Design hydrographs ideally should mimic the general volume, peak, and shape of observed runoff hydrographs. Design hydrographs commonly are estimated in part by unit hydrographs. A unit hydrograph is defined as the runoff hydrograph that results from a unit pulse of excess rainfall uniformly distributed over the watershed at a constant rate for a specific duration. A time-distributed, watershed-loss model is required for modeling by unit hydrographs. This report develops a specific time-distributed, watershed-loss model known as an initial-abstraction, constant-loss model. For this watershed-loss model, a watershed is conceptualized to have the capacity to store or abstract an absolute depth of rainfall at and near the beginning of a storm. Depths of total rainfall less than this initial abstraction do not produce runoff. The watershed also is conceptualized to have the capacity to remove rainfall at a constant rate (loss) after the initial abstraction is satisfied. Additional rainfall inputs after the initial abstraction is satisfied contribute to runoff if the rainfall rate (intensity) is larger than the constant loss. The initial abstraction, constant-loss model thus is a two-parameter model. The initial-abstraction, constant-loss model is investigated through detailed computational and statistical analysis of observed rainfall and runoff data for 92 USGS streamflow-gaging stations (watersheds) in Texas with contributing drainage areas from 0.26 to 166 square miles. The analysis is

  13. Abstract Model of the SATS Concept of Operations: Initial Results and Recommendations

    NASA Technical Reports Server (NTRS)

    Dowek, Gilles; Munoz, Cesar; Carreno, Victor A.

    2004-01-01

    An abstract mathematical model of the concept of operations for the Small Aircraft Transportation System (SATS) is presented. The Concept of Operations consist of several procedures that describe nominal operations for SATS, Several safety properties of the system are proven using formal techniques. The final goal of the verification effort is to show that under nominal operations, aircraft are safely separated. The abstract model was written and formally verified in the Prototype Verification System (PVS).

  14. COMPETITIVE METAGENOMIC DNA HYBRIDIZATION IDENTIFIES HOST-SPECIFIC GENETIC MARKERS IN CATTLE FECAL SAMPLES - ABSTRACT

    EPA Science Inventory

    Several PCR methods have recently been developed to identify fecal contamination in surface waters. In all cases, researchers have relied on one gene or one microorganism for selection of host specific markers. Here, we describe the application of a genome fragment enrichment met...

  15. (abstract) Using GPS Measurements to Identify Global Ionospheric Storms in Near Real-Time

    NASA Technical Reports Server (NTRS)

    Ho, C. M.; Mannucci, A. J.; Lindqwister, U. J.; Rao, A. M.; Pi, X.; Wilson, B. D.; Yuan, D. N.; Reyes, M.

    1996-01-01

    The solar wind interacts with the Earth's magnetosphere, eventually dissipating energy into the ionosphere and atmosphere. As a terminator, the ionosphere responds to magnetic storms, which is very important in understanding the energy coupling process between the Sun and the Earth and in forecasting space weather changes.The worldwide GPS network, for the first time, makes near real-time global ionospheric TEC measurements a possibility. Based on these measurements, global ionospheric TEC maps are generated with time resolution of from 5 minutes to hours. Using these maps, we can analyze the global evolution of ionospheric storms on temporal and spatial scales, which have been dificult to study before. We find that for certain types of storms (such as TID-driven), it is possible to identify them near onset and issue warning signals during the early stages. Main attention has been paid on northern hemispheric winter storms. Their common features and physical mechanisms are being investigated.

  16. Obama's American Graduation Initiative: Race, Conservative Modernization, and a Logic of Abstraction

    ERIC Educational Resources Information Center

    Kuntz, Aaron M.; Gildersleeve, Ryan Evely; Pasque, Penny A.

    2011-01-01

    The American Graduation Initiative stands as the cornerstone of the Obama administration's higher education agenda. To investigate the state of the politics of education in the Age of Obama, this article employs critical discourse analysis to unveil the hidden meanings and ideological commitments inherent in Obama's policy discourse. Read within…

  17. On the competition between hydrogen abstraction versus C-O bond fission in initiating dimethyl ether combustion

    SciTech Connect

    Francisco, J.

    1999-07-01

    There has been a growing interest in the potential use of dimethyl ether (DME) as a diesel fuel in compression ignition engines. There are two initiation steps involved in the combustion of DME, one involving C-O bond fission and the other involving hydrogen abstraction by molecular oxygen. The kinetics and thermodynamics of C-O bond fission were explored computationally in a previous paper. The present paper addresses the competing process--hydrogen abstraction by molecular oxygen. Ab initio molecular orbital calculations are used to study the structures and energetics of the reactants, products, and the transition state for the CH{sub 3}OCH{sub 3} + O{sub 2} reaction. The calculations predict a barrier for hydrogen abstraction from CH{sub 3}OCH{sub 3} by O{sub 2} of 47.4 kcal/mol. This is lower than the barrier height for C-O bond fission previously calculated to be 81.1 kcal/mol. The results support values used in current models for the combustion of DME. Moreover, an examination of rates for C-O bond fission versus hydrogen abstraction by O{sub 2} suggests that the bimolecular process is the dominant pathway.

  18. Theoretical study of the oxidation mechanisms of naphthalene initiated by hydroxyl radicals: the H abstraction pathway.

    PubMed

    Shiroudi, Abolfazl; Deleuze, Michael S

    2014-05-22

    Reaction mechanisms for the initial stages of naphthalene oxidation at high temperatures (T ≥ 600 K) have been studied theoretically using density functional theory along with various exchange-correlation functionals, as well as the benchmark CBS-QB3 quantum chemical approach. These stages correspond to the removal of hydrogen atoms by hydroxyl radical and the formation thereby of 1- and 2-naphthyl radicals. Bimolecular kinetic rate constants were estimated by means of transition state theory. The excellent agreement with the available experimental kinetic rate constants demonstrates that a two-step reaction scheme prevails. Comparison with results obtained with density functional theory in conjunction with various exchange-correlation functionals also shows that DFT remains unsuited for quantitative insights into kinetic rate constants. Analysis of the computed structures, bond orders, and free energy profiles demonstrates that the reaction steps involved in the removal of hydrogen atoms by OH radicals satisfy Hammond's principle. Computations of branching ratios also show that these reactions do not exhibit a particularly pronounced site-selectivity.

  19. Initial Progress of Children Identified with Disabilities in Michigan's Reading First Schools

    ERIC Educational Resources Information Center

    Katz, Lauren A.; Stone, C. Addison; Carlisle, Joanne F.; Corey, Douglas Lyman; Zeng, Ji

    2008-01-01

    This 2-year longitudinal study examined initial evidence of progress in reading for 1,512 children with and without identified speech-language and/or learning disabilities (LD-SLD) in the context of the explicit literacy instruction provided in Michigan's Reading First (RF)schools. The findings suggested that children with LD-SLD labels…

  20. Expression profiling identifies genes expressed early during lint fibre initiation in cotton.

    PubMed

    Wu, Yingru; Machado, Adriane C; White, Rosemary G; Llewellyn, Danny J; Dennis, Elizabeth S

    2006-01-01

    Cotton fibres are a subset of single epidermal cells that elongate from the seed coat to produce the long cellulose strands or lint used for spinning into yarn. To identify genes that might regulate lint fibre initiation, expression profiles of 0 days post-anthesis (dpa) whole ovules from six reduced fibre or fibreless mutants were compared with wild-type linted cotton using cDNA microarrays. Numerous clones were differentially expressed, but when only those genes that are normally expressed in the ovule outer integument (where fibres develop) were considered, just 13 different cDNA clones were down-regulated in some or all of the mutants. These included: a Myb transcription factor (GhMyb25) similar to the Antirrhinum Myb AmMIXTA, a putative homeodomain protein (related to Arabidopsis ATML1), a cyclin D gene, some previously identified fibre-expressed structural and metabolic genes, such as lipid transfer protein, alpha-expansin and sucrose synthase, as well as some unknown genes. Laser capture microdissection and reverse transcription-PCR were used to show that both the GhMyb25 and the homeodomain gene were predominantly ovule specific and were up-regulated on the day of anthesis in fibre initials relative to adjacent non-fibre ovule epidermal cells. Their spatial and temporal expression pattern therefore coincided with the time and location of fibre initiation. Constitutive overexpression of GhMyb25 in transgenic tobacco resulted in an increase in branched long-stalked leaf trichomes. The involvement of cell cycle genes prompted DNA content measurements that indicated that fibre initials, like leaf trichomes, undergo DNA endoreduplication. Cotton fibre initiation therefore has some parallels with leaf trichome development, although the detailed molecular mechanisms are clearly different.

  1. Abstraction and Consolidation

    ERIC Educational Resources Information Center

    Monaghan, John; Ozmantar, Mehmet Fatih

    2004-01-01

    What is involved in consolidating a new mathematical abstraction? This paper examines the work of one student who was working on a task designed to consolidate two recently constructed absolute function abstractions. The study adopts an activity theoretic model of abstraction in context. Selected protocol data are presented. The initial state of…

  2. Hospital discharge abstracts have limited accuracy in identifying occurrence of Clostridium difficile infections among hospitalized individuals with inflammatory bowel disease: A population-based study

    PubMed Central

    Singh, Harminder; Nugent, Zoann; Yu, B. Nancy; Lix, Lisa M.; Targownik, Laura; Bernstein, Charles

    2017-01-01

    Background Hospital discharge databases are used to study the epidemiology of Clostridium difficile infections (CDI) among hospitalized patients with inflammatory bowel disease (IBD). CDI in IBD is increasingly important and accurately estimating its occurrence is critical in understanding its comorbidity. There are limited data on the reliability of the International Classification of Diseases 10th revision (ICD-10) (now widely used in North America) CDI code in determining occurrence of CDI among hospitalized patients. We compared the performance of ICD-10 CDI coding to laboratory confirmed CDI diagnoses. Methods The University of Manitoba IBD Epidemiology Database was used to identify individuals with and without IBD discharged with CDI diagnoses between 07/01/2005 and 3/31/2014. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of ICD-10 CDI code was compared to laboratory CDI diagnoses recorded in a province wide CDI dataset. Multivariable logistic regression models were performed to test the predictors of diagnostic inaccuracy of ICD-10 CDI code. Results There were 273 episodes of laboratory confirmed CDI (hospitalized and non-hospitalized) among 7396 individuals with IBD and 536 among 66,297 matched controls. The sensitivity, specificity, PPV and NPV of ICD-10 CDI code in discharge abstracts was 72.8%, 99.6%, 64.1% and 99.7% among those with IBD and 70.8%, 99.9%, 79.0% and 99.9% among those without IBD. Predictors of diagnostic inaccuracy included IBD, older age, increased co-morbidity and earlier years of hospitalization. Conclusions Identification of CDI using ICD-10 CDI code in hospital discharge abstracts may not identify up to 30% of CDI cases, with worse performance among those with IBD. PMID:28199401

  3. An integrated approach towards identifying age-related mechanisms of slip initiated falls

    PubMed Central

    Lockhart, Thurmon E.

    2008-01-01

    The causes of slip and fall accidents, both in terms of extrinsic and intrinsic factors and their associations are not yet fully understood. Successful intervention solutions for reducing slip and fall accidents require a more complete understanding of the mechanisms involved. Before effective fall prevention strategies can be put into practice, it is central to examine the chain of events in an accident, comprising the exposure to hazards, initiation of events and the final outcome leading to injury and disability. These events can be effectively identified and analyzed by applying epidemiological, psychophysical, biomechanical and tribological research principles and methodologies. In this manuscript, various methods available to examine fall accidents and their underlying mechanisms are presented to provide a comprehensive array of information to help pinpoint the needs and requirements of new interventions aimed at reducing the risk of falls among the growing elderly population. PMID:17768070

  4. Exploiting jet binning to identify the initial state of high-mass resonances

    NASA Astrophysics Data System (ADS)

    Ebert, Markus A.; Liebler, Stefan; Moult, Ian; Stewart, Iain W.; Tackmann, Frank J.; Tackmann, Kerstin; Zeune, Lisa

    2016-09-01

    If a new high-mass resonance is discovered at the Large Hadron Collider, model-independent techniques to identify the production mechanism will be crucial to understand its nature and effective couplings to Standard Model particles. We present a powerful and model-independent method to infer the initial state in the production of any high-mass color-singlet system by using a tight veto on accompanying hadronic jets to divide the data into two mutually exclusive event samples (jet bins). For a resonance of several hundred GeV, the jet binning cut needed to discriminate quark and gluon initial states is in the experimentally accessible range of several tens of GeV. It also yields comparable cross sections for both bins, making this method viable already with the small event samples available shortly after a discovery. Theoretically, the method is made feasible by utilizing an effective field theory setup to compute the jet cut dependence precisely and model independently and to systematically control all sources of theoretical uncertainties in the jet binning, as well as their correlations. We use a 750 GeV scalar resonance as an example to demonstrate the viability of our method.

  5. On a possible methodology for identifying the initiation of damage of a class of polymeric materials

    NASA Astrophysics Data System (ADS)

    Alagappan, P.; Kannan, K.; Rajagopal, K. R.

    2016-08-01

    In this paper, we provide a possible methodology for identifying the initiation of damage in a class of polymeric solids. Unlike most approaches to damage that introduce a damage parameter, which might be a scalar, vector or tensor, that depends on the stress or strain (that requires knowledge of an appropriate reference configuration in which the body was stress free and/or without any strain), we exploit knowledge of the fact that damage is invariably a consequence of the inhomogeneity of the body that makes the body locally `weak' and the fact that the material properties of a body invariably depend on the density, among other variables that can be defined in the current configuration, of the body. This allows us to use density, for a class of polymeric materials, as a means to identify incipient damage in the body. The calculations that are carried out for the biaxial stretch of an inhomogeneous multi-network polymeric solid bears out the appropriateness of the thesis that the density of the body can be used to forecast the occurrence of damage, with the predictions of the theory agreeing well with experimental results. The study also suggests a meaningful damage criterion for the class of bodies being considered.

  6. Exploring the Synoptic Differences Between MJO Initiation Events Identified by Multiple Algorithms

    NASA Astrophysics Data System (ADS)

    Vargas Martes, R. M.; Hartten, L. M.

    2015-12-01

    The Madden-Julian Oscillation (MJO) is a tropical phenomenon that develops over the Indian Ocean. This intraseasonal oscillation consists of an extensive area of convection, about 1000 km across, that releases latent heat in the mid-troposphere, and this heating forces planetary-scale waves to travel through the upper troposphere. These waves can affect weather and climate in the extratropical regions. Since our computational models do not simulate the MJO correctly, international efforts are underway to improve our understanding of the processes involved, especially during the MJO's early stages. This study examines and compares MJO initiation events and types (primary, intensifying, non-MJO) identified by researchers using four methods during 1998-2009 boreal winters. Two methods focused on the precipitation aspect of the oscillation, and the others focused on circulation. Five variables were selected for analysis: temperature at 400 hPa, outgoing long-wave radiation (OLR), sea level pressure (SLP), and zonal winds at 200 and 850 hPa. Twelve MJO events were selected, and four were analyzed. The five variables' contributions to each event were mapped using the MJO-like mode recently identified by other scientists from unfiltered five-day mean gridded data. These visualizations show consistent behaviors in OLR, temperature, and SLP. Positive OLR anomalies occurred in the Indian Ocean before MJO convection began, supporting another research group's idea of an MJO "dry dynamic mode." The MJO-like mode also depicts some previously observed behavior in MJO precursor variables. The results also serve to validate the MJO-like mode and demonstrate that it identifies both MJO and non-MJO convection.

  7. Identifying initial molecular targets of PDT: protein and lipid oxidation products

    NASA Astrophysics Data System (ADS)

    Oleinick, Nancy L.; Kim, Junhwan; Rodriguez, Myriam E.; Xue, Liang-yan; Kenney, Malcolm E.; Anderson, Vernon E.

    2009-06-01

    Photodynamic Therapy (PDT) generates singlet oxygen (1O2) which oxidizes biomolecules in the immediate vicinity of its formation. The phthalocyanine photosensitizer Pc 4 localizes to mitochondria and endoplasmic reticulum, and the primary targets of Pc 4-PDT are expected to be lipids and proteins of those membranes. The initial damage then causes apoptosis in cancer cells via the release of cytochrome c (Cyt-c) from mitochondria into the cytosol, followed by the activation of caspases. That damage also triggers the induction of autophagy, an attempt by the cells to eliminate damaged organelles, or when damage is too extensive, to promote cell death. Cyt-c is bound to the cytosolic side of the mitochondrial inner membrane through association with cardiolipin (CL), a phospholipid containing four unsaturated fatty acids and thus easily oxidized by 1O2 or by other oxidizing agents. Increasing evidence suggests that oxidation of CL loosens its association with Cyt-c, and that the peroxidase activity of Cyt-c can oxidize CL. In earlier studies of Cyt-c in homogeneous medium by MALDI-TOF-MS and LC-ESI-MS, we showed that 1O2 generated by Pc 4-PDT oxidized histidine, methionine, tryptophan, and unexpectedly phenylalanine but not tyrosine. Most of the oxidation products were known to be formed by other oxidizing agents, such as hydroxyl radical, superoxide radical anion, and peroxynitrite. However, two products of histidine were unique to 1O2 and may be useful for reporting the action of 1O2 in cells and tissues. These products, as well as CL oxidation products, have now been identified in liposomes and mitochondria after Pc 4-PDT. In mitochondria, the PDT dose-dependent oxidations can be related to specific changes in mitochondrial function, Bcl-2 photodamage, and Cyt-c release. Thus, the role of PDT-generated 1O2 in oxidizing Cyt-c and CL and the interplay between protein and lipid targets may be highly relevant to understanding one mechanism for cell killing by PDT.

  8. A framework for identifying the applicability of heating or cooling technologies based on initial project information

    NASA Astrophysics Data System (ADS)

    Cacace, Katie Meng

    In order to fully achieve the energy savings and human comfort benefits of many alternative heating and cooling technologies, design considerations for these technologies must be made during the conceptual design stage. However, at this stage architects are often faced with challenges that inhibit the integration of such technologies. At the early stages of design, architects have limited time and technical knowledge to research alternative technologies and mechanical engineers are typically not yet part of the design team to offer their expertise. To address these problems, this research developed a framework for a Technology Identifier that would inform an architect about alternative heating and cooling technologies that are applicable to their specific project at the conceptual design stage. The framework is based on the premise that a quantitative relationship between the initial project information and a technology's critical output variable(s) for heat transfer to the space can be established. Therefore, to be included in the framework a technology must possess a component that provides direct heat transfer to the space for the framework to determine if the technology can maintain the desired space temperature. The climatic influences on a technology's performance and the effect of changing a technology's input variables on the heat transfer output variable(s) were also quantified. Existing building energy simulation programs were used in these analyses. The framework develops simulation input files for multiple technologies, utilizes existing simulation programs to predict the performance of these technologies, and then displays the output results along with other information that is useful to designers at the conceptual stage. Each simulation input file is compiled from a template that queries databases and requires minimal user input. The output display includes the space temperature, energy consumption, and design considerations of each technology. A

  9. Research Abstracts.

    ERIC Educational Resources Information Center

    Plotnick, Eric

    2001-01-01

    Presents research abstracts from the ERIC Clearinghouse on Information and Technology. Topics include: classroom communication apprehension and distance education; outcomes of a distance-delivered science course; the NASA/Kennedy Space Center Virtual Science Mentor program; survey of traditional and distance learning higher education members;…

  10. Research Abstracts.

    ERIC Educational Resources Information Center

    Plotnik, Eric

    2001-01-01

    Presents six research abstracts from the ERIC (Educational Resources Information Center) database. Topics include: effectiveness of distance versus traditional on-campus education; improved attribution recall from diversification of environmental context during computer-based instruction; qualitative analysis of situated Web-based learning;…

  11. Abstract Constructions.

    ERIC Educational Resources Information Center

    Pietropola, Anne

    1998-01-01

    Describes a lesson designed to culminate a year of eighth-grade art classes in which students explore elements of design and space by creating 3-D abstract constructions. Outlines the process of using foam board and markers to create various shapes and optical effects. (DSK)

  12. The Talents Dovetail: Initiative for Identifying Gifted and Talented Minority Students.

    ERIC Educational Resources Information Center

    Talents Unlimited, Inc., Mobile, AL.

    The Talents Unlimited (TU) critical and creative thinking skills model is designed to help teachers recognize and nurture the multiple talents of all children. Research based on the work of Calvin Taylor, has identified high-level talent areas of productive thinking, communication, forecasting, decision making, and planning, in which all excel to…

  13. African American Young Adult Smoking Initiation: Identifying Intervention Points and Prevention Opportunities

    ERIC Educational Resources Information Center

    Cheney, Marshall K.; Mansker, Jacqueline

    2014-01-01

    Background: African Americans have one of the lowest smoking rates as teens yet have one of the highest smoking rates as adults. Approximately 40% of African Americans who have ever smoked started smoking between the ages of 18 and 21. Purpose: This study aimed to identify why African American young adults began smoking in young adulthood and what…

  14. Abstraction and Problem Reformulation

    NASA Technical Reports Server (NTRS)

    Giunchiglia, Fausto

    1992-01-01

    In work done jointly with Toby Walsh, the author has provided a sound theoretical foundation to the process of reasoning with abstraction (GW90c, GWS9, GW9Ob, GW90a). The notion of abstraction formalized in this work can be informally described as: (property 1), the process of mapping a representation of a problem, called (following historical convention (Sac74)) the 'ground' representation, onto a new representation, called the 'abstract' representation, which, (property 2) helps deal with the problem in the original search space by preserving certain desirable properties and (property 3) is simpler to handle as it is constructed from the ground representation by "throwing away details". One desirable property preserved by an abstraction is provability; often there is a relationship between provability in the ground representation and provability in the abstract representation. Another can be deduction or, possibly inconsistency. By 'throwing away details' we usually mean that the problem is described in a language with a smaller search space (for instance a propositional language or a language without variables) in which formulae of the abstract representation are obtained from the formulae of the ground representation by the use of some terminating rewriting technique. Often we require that the use of abstraction results in more efficient .reasoning. However, it might simply increase the number of facts asserted (eg. by allowing, in practice, the exploration of deeper search spaces or by implementing some form of learning). Among all abstractions, three very important classes have been identified. They relate the set of facts provable in the ground space to those provable in the abstract space. We call: TI abstractions all those abstractions where the abstractions of all the provable facts of the ground space are provable in the abstract space; TD abstractions all those abstractions wllere the 'unabstractions' of all the provable facts of the abstract space are

  15. LGR5 and Nanog identify stem cell signature of pancreas beta cells which initiate pancreatic cancer.

    PubMed

    Amsterdam, Abraham; Raanan, Calanit; Schreiber, Letizia; Polin, Nava; Givol, David

    2013-04-05

    Pancreas cancer, is the fourth leading cause of cancer death but its cell of origin is controversial. We compared the localization of stem cells in normal and cancerous pancreas using antibodies to the stem cell markers Nanog and LGR5. Here we show, for the first time, that LGR5 is expressed in normal pancreas, exclusively in the islets of Langerhans and it is co-localized, surprisingly, with Nanog and insulin in clusters of beta cells. In cancerous pancreas Nanog and LGR5 are expressed in the remaining islets and in all ductal cancer cells. We observed insulin staining among the ductal cancer cells, but not in metastases. This indicates that the islet's beta cells, expressing LGR5 and Nanog markers are the initiating cells of pancreas cancer, which migrated from the islets to form the ductal cancerous tissue, probably after mutation and de-differentiation. This discovery may facilitate treatment of this devastating cancer.

  16. Applying deep learning technology to automatically identify metaphase chromosomes using scanning microscopic images: an initial investigation

    NASA Astrophysics Data System (ADS)

    Qiu, Yuchen; Lu, Xianglan; Yan, Shiju; Tan, Maxine; Cheng, Samuel; Li, Shibo; Liu, Hong; Zheng, Bin

    2016-03-01

    Automated high throughput scanning microscopy is a fast developing screening technology used in cytogenetic laboratories for the diagnosis of leukemia or other genetic diseases. However, one of the major challenges of using this new technology is how to efficiently detect the analyzable metaphase chromosomes during the scanning process. The purpose of this investigation is to develop a computer aided detection (CAD) scheme based on deep learning technology, which can identify the metaphase chromosomes with high accuracy. The CAD scheme includes an eight layer neural network. The first six layers compose of an automatic feature extraction module, which has an architecture of three convolution-max-pooling layer pairs. The 1st, 2nd and 3rd pair contains 30, 20, 20 feature maps, respectively. The seventh and eighth layers compose of a multiple layer perception (MLP) based classifier, which is used to identify the analyzable metaphase chromosomes. The performance of new CAD scheme was assessed by receiver operation characteristic (ROC) method. A number of 150 regions of interest (ROIs) were selected to test the performance of our new CAD scheme. Each ROI contains either interphase cell or metaphase chromosomes. The results indicate that new scheme is able to achieve an area under the ROC curve (AUC) of 0.886+/-0.043. This investigation demonstrates that applying a deep learning technique may enable to significantly improve the accuracy of the metaphase chromosome detection using a scanning microscopic imaging technology in the future.

  17. IDENTIFYING AND TARGETING TUMOR-INITIATING CELLS IN THE TREATMENT OF BREAST CANCER

    PubMed Central

    Wei, Wei; Lewis, Michael T.

    2015-01-01

    Breast cancer is the most common cancer in women (exclusive of skin cancer), and is the second leading cause of cancer-related deaths. Although conventional and targeted therapies have improved survival rates, there are still considerable challenges in treating breast cancer, including treatment resistance, disease recurrence, and metastasis. Treatment resistance can be either de novo - due to traits that tumor cells possess prior to treatment, or acquired, - due to traits that tumor cells gain in response to treatment. A recently proposed mechanism of de novo resistance invokes existence of a specialized subset of cancer cells defined as tumor-initiating cells (TICs), or cancer stem cells (CSC). TICs have the capacity to self-renew and regenerate new tumors that consist of all clonally-derived cell types present in the parental tumor. There are data to suggest that TICs are resistant to many conventional cancer therapies, and survive treatment in spite of dramatic shrinkage of the tumor. Residual TICs can then eventually regrow resulting in disease relapse. It is also hypothesized that TIC may be responsible for metastatic disease. If these hypotheses are correct, targeting TICs may be imperative to achieve cure. In this review, we discuss evidence for breast TICs and their apparent resistance to conventional chemotherapy and radiotherapy, as well as to various targeted therapies. We also address the potential impact of breast TIC plasticity and metastatic potential on therapeutic strategies. Finally, we describe several genes and signaling pathways that appear important for TIC function that may represent promising therapeutic targets. PMID:25876646

  18. Initial Assessment of the Pathogenic Mechanisms of the recently identified Alzheimer Risk Loci

    PubMed Central

    Holton, Patrick; Ryten, Mina; Nalls, Michael; Trabzuni, Daniah; Weale, Michael E.; Hernandez, Dena; Crehan, Helen; Gibbs, J. Raphael; Mayeux, Richard; Haines, Jonathan L.; Farrer, Lindsay A.; Pericak-Vance, Margaret A.; Schellenberg, Gerard D.; Ramirez-Restrepo, Manuel; Engel, Anzhelika; Myers, Amanda J.; Corneveaux, Jason J.; Huentelman, Matthew J.; Dillman, Allissa; Cookson, Mark R.; Reiman, Eric M.; Singleton, Andrew; Hardy, John; Guerreiro, Rita

    2012-01-01

    SUMMARY Recent genome wide association studies have identified CLU, CR1, ABCA7 BIN1, PICALM and MS4A6A/MS4A6E in addition to the long established APOE, as loci for Alzheimer’s disease. We have systematically examined each of these loci to assess whether common coding variability contributes to the risk of disease. We have also assessed the regional expression of all the genes in the brain and whether there is evidence of an eQTL explaining the risk. In agreement with other studies we find that coding variability may explain the ABCA7 association, but common coding variability does not explain any of the other loci. We were not able to show that any of the loci had eQTLs within the power of this study. Furthermore the regional expression of each of the loci did not match the pattern of brain regional distribution in Alzheimer pathology. Although these results are mainly negative, they allow us to start defining more realistic alternative approaches to determine the role of all the genetic loci involved in Alzheimer’s disease. PMID:23360175

  19. Initial characterization of Pf62, a novel protein of Plasmodium falciparum identified by immunoscreening.

    PubMed

    Moyano, Eva M; González, Luis Miguel; Montero, Estrella; Cuevas, Laureano; Perez-Pastrana, Esperanza; Santa-Maria, Ysmael; Benito, Agustín

    2009-06-01

    In order to find new antigens from Plasmodium falciparum, a complementary DNA (cDNA) library was constructed and screened. The study of expression library of P. falciparum was performed in an attempt to identify new antigens that could have potential relevance for the falciparum-malaria diagnosis and/or protection. Between the positive clones detected (ring erythrocyte surface antigen, merozoite erythrocyte surface antigen, RHOP H3, CSP, LSA), a new gene that correspond to a new protein (Pf62) was isolated and characterized. This antigen was useful for the diagnosis of malaria in enzyme-linked immunosorbent assay tests. The cDNA corresponding to this antigen and structure of the gene were characterized. Pf62 is a single copy gene that contains one exon. The Pf62 cDNA has an open reading frame of 1,599 nucleotides that code for a putative protein of 532 amino acids with a predicted molecular mass of 62 kDa. The polypeptide contains in the central section two regions of repeats of 21 and 19 amino acids, respectively. The localization of the Pf62 protein was performed by immunoblot, indirect immunofluorescence assay and immunoelectron microscopy. Pf62 is localized in the cytoplasm of the parasite and also on the surface of the infected erythrocyte. Serologic assays by using synthetic peptides designed from different antigenic regions of the Pf62 protein resulted in acceptable data of sensitivity and specificity in symptomatic malaria patients.

  20. Identifying and characterizing transboundary aquifers along the Mexico-US border: An initial assessment

    NASA Astrophysics Data System (ADS)

    Sanchez, Rosario; Lopez, Victoria; Eckstein, Gabriel

    2016-04-01

    The transboundary nature of water dividing Mexico and the United States (U.S.) transforms the entire border region into an instrument of cooperation, a source of conflict, a national security issue, and an environmental concern. Reasonable data collection and research analysis have been conducted for surface waters by joint governmental institutions and non-governmental bodies. However, with the exception of the U.S. Transboundary Assessment Act Program (TAAP) (focusing on the Hueco Bolson, Mesilla Bolson, San Pedro and Santa Cruz aquifers), there is no comparable research, institutional development, or assessment of transboundary groundwater issues on the frontier. Moreover, data collection and methodologies vary between the two countries, there is no broadly accepted definition of the transboundary nature of an aquifer, and available legal and policy frameworks are constrained by non-hydrological considerations. Hence, there is a conceptual and institutional void regarding transboundary groundwater resources between Mexico and the U.S. The purpose of this paper is to bridge this void and characterize transboundary aquifers on the Mexico-US border. It reviews existing international frameworks for identifying hydrological and social criteria that characterize an aquifer as transboundary. It then assesses data from both countries to propose where and which aquifers could be considered transboundary. Finally, the paper proposes an agenda for assessing Mexico-US transboundary aquifers as a means for improving groundwater management in the border region.

  1. Identifying generalities in data sets using periodic Hopfield networks : initial status report.

    SciTech Connect

    Link, Hamilton E.; Backer, Alejandro

    2004-12-01

    We present a novel class of dynamic neural networks that is capable of learning, in an unsupervised manner, attractors that correspond to generalities in a data set. Upon presentation of a test stimulus, the networks follow a sequence of attractors that correspond to subsets of increasing size or generality in the original data set. The networks, inspired by those of the insect antennal lobe, build upon a modified Hopfield network in which nodes are periodically suppressed, global inhibition is gradually strengthened, and the weight of input neurons is gradually decreased relative to recurrent connections. This allows the networks to converge on a Hopfield network's equilibrium within each suppression cycle, and to switch between attractors in between cycles. The fast mutually reinforcing excitatory connections that dominate dynamics within cycles ensures the robust error-tolerant behavior that characterizes Hopfield networks. The cyclic inhibition releases the network from what would otherwise be stable equilibriums or attractors. Increasing global inhibition and decreasing dependence on the input leads successive attractors to differ, and to display increasing generality. As the network is faced with stronger inhibition, only neurons connected with stronger mutually excitatory connections will remain on; successive attractors will consist of sets of neurons that are more strongly correlated, and will tend to select increasingly generic characteristics of the data. Using artificial data, we were able to identify configurations of the network that appeared to produce a sequence of increasingly general results. The next logical steps are to apply these networks to suitable real-world data that can be characterized by a hierarchy of increasing generality and observe the network's performance. This report describes the work, data, and results, the current understanding of the results, and how the work could be continued. The code, data, and preliminary results are

  2. Evaluation of 10 SLE susceptibility loci in Asian populations, which were initially identified in European populations

    PubMed Central

    Zhang, Yue-miao; Zhou, Xu-jie; Nath, Swapan K.; Sun, Celi; Zhao, Ming-hui; Zhang, Hong

    2017-01-01

    Ten novel loci have been found to be associated with systemic lupus erythematosus (SLE) susceptibility by a recent genome-wide association study conducted in Europeans. To test their disease associations and genetic similarities/differences in Asians and Europeans, we genotyped the 10 novel single nucleotide polymorphisms (SNPs) and performed an association study. A Chinese cohort from Northern China was recruited as the discovery population, and three East Asian cohorts were included for independent replication. The 10 SNPs were genotyped using TaqMan allele discrimination assays. To prioritize the associated SNPs, different layers of the public functional data were integrated. Among the 10 SNPs, rs564799 in IL12A was shared in both ethnicities (Padjust = 5.91 × 10−4; odds ratio = 1.22, 1.10–1.35). We also confirmed the reported polymorphism rs7726414 in TCF7 in the current study (Padjust = 4.12 × 10−8; odds ratio = 1.46, 1.28–1.66). The directions and magnitudes of the allelic effects for most of the 10 SNPs were comparable between Europeans and Asians. However, higher risk allele frequencies and population-attributable risk percentages were observed in Asians than in Europeans. We also identified the most likely functional SNPs at each locus. In conclusion, both genetic similarities and differences across ethnicities have been observed, providing further evidence for a genetic basis of the high incidence of SLE in Asian ancestry. PMID:28128292

  3. A Genetic Approach to Identifying Signal Transduction Mechanisms Initiated by Receptors for TGF-B-Related Factors.

    DTIC Science & Technology

    1998-10-01

    resistant to TGF-ß-induced growth arrest suggest that both types of receptors are required for signaling (Boyd and Massague, 1989; Laiho et ah, 1990...II in TGF-ß- resistant cell mutants implicates both receptor types in signal transduction. J. Biol. Chem. 265, 18518-18524. Lechleider, R. J., de...I-1 « -J AD GRANT NUMBER DAMD17-94-J-4339 TITLE: A Genetic Approach to Identifying Signal Transduction Mechanisms Initiated by Receptors

  4. Combining bulk sediment OSL and meteoric 10Be fingerprinting techniques to identify gully initiation sites and erosion depths

    NASA Astrophysics Data System (ADS)

    Portenga, E. W.; Bishop, P.; Rood, D. H.; Bierman, P. R.

    2017-02-01

    Deep erosional gullies dissect landscapes around the world. Existing erosion models focus on predicting where gullies might begin to erode, but identifying where existing gullies were initiated and under what conditions is difficult, especially when historical records are unavailable. Here we outline a new approach for fingerprinting alluvium and tracing it back to its source by combining bulk sediment optically stimulated luminescence (bulk OSL) and meteoric 10Be (10Bem) measurements made on gully-derived alluvium samples. In doing so, we identify where gully erosion was initiated and infer the conditions under which such erosion occurred. As both 10Bem and bulk OSL data have distinctive depth profiles in different uneroded and depositional settings, we are able to identify the likely incision depths in potential alluvium source areas. We demonstrate our technique at Birchams Creek in the southeastern Australian Tablelands—a well-studied and recent example of gully incision that exemplifies a regional landscape transition from unchanneled swampy meadow wetlands to gully incision and subsequent wetland burial by post-European settlement alluvium. We find that such historic alluvium was derived from a shallow erosion of valley fill upstream of former swampy meadows and was deposited down the center of the valley. Incision likely followed catchment deforestation and the introduction of livestock, which overgrazed and congregated in valley bottoms in the early 20th century during a period of drought. As a result, severe gully erosion was likely initiated in localized, compacted, and oversteepened reaches of the valley bottom.

  5. Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component.

    PubMed

    Stoop, Esther J M; Schipper, Tim; Rosendahl Huber, Sietske K; Nezhinsky, Alexander E; Verbeek, Fons J; Gurcha, Sudagar S; Besra, Gurdyal S; Vandenbroucke-Grauls, Christina M J E; Bitter, Wilbert; van der Sar, Astrid M

    2011-07-01

    The hallmark of tuberculosis (TB) is the formation of granulomas, which are clusters of infected macrophages surrounded by additional macrophages, neutrophils and lymphocytes. Although it has long been thought that granulomas are beneficial for the host, there is evidence that mycobacteria also promote the formation of these structures. In this study, we aimed to identify new mycobacterial factors involved in the initial stages of granuloma formation. We exploited the zebrafish embryo Mycobacterium marinum infection model to study initiation of granuloma formation and developed an in vivo screen to select for random M. marinum mutants that were unable to induce granuloma formation efficiently. Upon screening 200 mutants, three mutants repeatedly initiated reduced granuloma formation. One of the mutants was found to be defective in the espL gene, which is located in the ESX-1 cluster. The ESX-1 cluster is disrupted in the Mycobacterium bovis BCG vaccine strain and encodes a specialized secretion system known to be important for granuloma formation and virulence. Although espL has not been implicated in protein secretion before, we observed a strong effect on the secretion of the ESX-1 substrates ESAT-6 and EspE. We conclude that our zebrafish embryo M. marinum screen is a useful tool to identify mycobacterial genes involved in the initial stages of granuloma formation and that we have identified a new component of the ESX-1 secretion system. We are confident that our approach will contribute to the knowledge of mycobacterial virulence and could be helpful for the development of new TB vaccines.

  6. Antibiotic discovery throughout the Small World Initiative: A molecular strategy to identify biosynthetic gene clusters involved in antagonistic activity.

    PubMed

    Davis, Elizabeth; Sloan, Tyler; Aurelius, Krista; Barbour, Angela; Bodey, Elijah; Clark, Brigette; Dennis, Celeste; Drown, Rachel; Fleming, Megan; Humbert, Allison; Glasgo, Elizabeth; Kerns, Trent; Lingro, Kelly; McMillin, MacKenzie; Meyer, Aaron; Pope, Breanna; Stalevicz, April; Steffen, Brittney; Steindl, Austin; Williams, Carolyn; Wimberley, Carmen; Zenas, Robert; Butela, Kristen; Wildschutte, Hans

    2017-01-22

    The emergence of bacterial pathogens resistant to all known antibiotics is a global health crisis. Adding to this problem is that major pharmaceutical companies have shifted away from antibiotic discovery due to low profitability. As a result, the pipeline of new antibiotics is essentially dry and many bacteria now resist the effects of most commonly used drugs. To address this global health concern, citizen science through the Small World Initiative (SWI) was formed in 2012. As part of SWI, students isolate bacteria from their local environments, characterize the strains, and assay for antibiotic production. During the 2015 fall semester at Bowling Green State University, students isolated 77 soil-derived bacteria and genetically characterized strains using the 16S rRNA gene, identified strains exhibiting antagonistic activity, and performed an expanded SWI workflow using transposon mutagenesis to identify a biosynthetic gene cluster involved in toxigenic compound production. We identified one mutant with loss of antagonistic activity and through subsequent whole-genome sequencing and linker-mediated PCR identified a 24.9 kb biosynthetic gene locus likely involved in inhibitory activity in that mutant. Further assessment against human pathogens demonstrated the inhibition of Bacillus cereus, Listeria monocytogenes, and methicillin-resistant Staphylococcus aureus in the presence of this compound, thus supporting our molecular strategy as an effective research pipeline for SWI antibiotic discovery and genetic characterization.

  7. Can traditional birth attendants be trained to accurately identify septic infants, initiate antibiotics, and refer in a rural African setting?

    PubMed Central

    Gill, Christopher John; MacLeod, William B; Phiri-Mazala, Grace; Guerina, Nicholas G; Mirochnick, Mark; Knapp, Anna B; Hamer, Davidson H

    2014-01-01

    ABSTRACT Background: Neonatal sepsis is a major cause of neonatal mortality. In populations with limited access to health care, early identification of bacterial infections and initiation of antibiotics by community health workers (CHWs) could be lifesaving. It is unknown whether this strategy would be feasible using traditional birth attendants (TBAs), a cadre of CHWs who typically have limited training and educational backgrounds. Methods: We analyzed data from the intervention arm of a cluster-randomized trial involving TBAs in Lufwanyama District, Zambia, from June 2006 to November 2008. TBAs followed neonates for signs of potential infection through 28 days of life. If any of 16 criteria were met, TBAs administered oral amoxicillin and facilitated referral to a rural health center. Results: Our analysis included 1,889 neonates with final vital status by day 28. TBAs conducted a median of 2 (interquartile range 2–6) home visits (51.4% in week 1 and 48.2% in weeks 2–4) and referred 208 neonates (11%) for suspected sepsis. Of referred neonates, 176/208 (84.6%) completed their referral. Among neonates given amoxicillin, 171/183 (93.4%) were referred; among referred neonates, 171/208 (82.2%) received amoxicillin. Referral and/or initiation of antibiotics were strongly associated with neonatal death (for referral, relative risk [RR] = 7.93, 95% confidence interval [CI] = 4.4–14.3; for amoxicillin administration, RR = 4.7, 95% CI = 2.4–8.7). Neonates clinically judged to be “extremely sick” by the referring TBA were at greatest risk of death (RR = 8.61, 95% CI = 4.0–18.5). Conclusion: The strategy of administering a first dose of antibiotics and referring based solely on the clinical evaluation of a TBA is feasible and could be effective in reducing neonatal mortality in remote rural settings. PMID:25276591

  8. Identifying Armed Respondents to Domestic Violence Restraining Orders and Recovering Their Firearms: Process Evaluation of an Initiative in California

    PubMed Central

    Frattaroli, Shannon; Claire, Barbara E.; Vittes, Katherine A.; Webster, Daniel W.

    2014-01-01

    Objectives. We evaluated a law enforcement initiative to screen respondents to domestic violence restraining orders for firearm ownership or possession and recover their firearms. Methods. The initiative was implemented in San Mateo and Butte counties in California from 2007 through 2010. We used descriptive methods to evaluate the screening process and recovery effort in each county, relying on records for individual cases. Results. Screening relied on an archive of firearm transactions, court records, and petitioner interviews; no single source was adequate. Screening linked 525 respondents (17.7%) in San Mateo County to firearms; 405 firearms were recovered from 119 (22.7%) of them. In Butte County, 88 (31.1%) respondents were linked to firearms; 260 firearms were recovered from 45 (51.1%) of them. Nonrecovery occurred most often when orders were never served or respondents denied having firearms. There were no reports of serious violence or injury. Conclusions. Recovering firearms from persons subject to domestic violence restraining orders is possible. We have identified design and implementation changes that may improve the screening process and the yield from recovery efforts. Larger implementation trials are needed. PMID:24328660

  9. Small molecule epigenetic screen identifies novel EZH2 and HDAC inhibitors that target glioblastoma brain tumor-initiating cells

    PubMed Central

    Grinshtein, Natalie; Rioseco, Constanza C.; Marcellus, Richard; Uehling, David; Aman, Ahmed; Lun, Xueqing; Muto, Osamu; Podmore, Lauren; Lever, Jake; Shen, Yaoqing; Blough, Michael D.; Cairncross, Greg J.; Robbins, Stephen M.; Jones, Steven J.; Marra, Marco A.; Al-Awar, Rima; Senger, Donna L.; Kaplan, David R.

    2016-01-01

    Glioblastoma (GBM) is the most lethal and aggressive adult brain tumor, requiring the development of efficacious therapeutics. Towards this goal, we screened five genetically distinct patient-derived brain-tumor initiating cell lines (BTIC) with a unique collection of small molecule epigenetic modulators from the Structural Genomics Consortium (SGC). We identified multiple hits that inhibited the growth of BTICs in vitro, and further evaluated the therapeutic potential of EZH2 and HDAC inhibitors due to the high relevance of these targets for GBM. We found that the novel SAM-competitive EZH2 inhibitor UNC1999 exhibited low micromolar cytotoxicity in vitro on a diverse collection of BTIC lines, synergized with dexamethasone (DEX) and suppressed tumor growth in vivo in combination with DEX. In addition, a unique brain-penetrant class I HDAC inhibitor exhibited cytotoxicity in vitro on a panel of BTIC lines and extended survival in combination with TMZ in an orthotopic BTIC model in vivo. Finally, a combination of EZH2 and HDAC inhibitors demonstrated synergy in vitro by augmenting apoptosis and increasing DNA damage. Our findings identify key epigenetic modulators in GBM that regulate BTIC growth and survival and highlight promising combination therapies. PMID:27449082

  10. Approved Instructional Resources Series: A National Initiative to Identify Quality Emergency Medicine Blog and Podcast Content for Resident Education.

    PubMed

    Lin, Michelle; Joshi, Nikita; Grock, Andrew; Swaminathan, Anand; Morley, Eric J; Branzetti, Jeremy; Taira, Taku; Ankel, Felix; Yarris, Lalena M

    2016-05-01

    Background Emergency medicine (EM) residency programs can provide up to 20% of their planned didactic experiences asynchronously through the Individualized Interactive Instruction (III) initiative. Although blogs and podcasts provide potential material for III content, programs often struggle with identifying quality online content. Objective To develop and implement a process to curate quality EM content on blogs and podcasts for resident education and III credit. Methods We developed the Approved Instructional Resources (AIR) Series on the Academic Life in Emergency Medicine website. Monthly, an editorial board identifies, peer reviews, and writes assessment questions for high-quality blog/podcast content. Eight educators rate each post using a standardized scoring instrument. Posts scoring ≥ 30 of 35 points are awarded an AIR badge and featured in the series. Enrolled residents can complete an assessment quiz for III credit. After 12 months of implementation, we report on program feasibility, enrollment rate, web analytics, and resident satisfaction scores. Results As of June 2015, 65 EM residency programs are enrolled in the AIR Series, and 2140 AIR quizzes have been completed. A total of 96% (2064 of 2140) of participants agree or strongly agree that the activity would improve their clinical competency, 98% (2098 of 2140) plan to use the AIR Series for III credit, and 97% (2077 of 2140) plan to use it again in the future. Conclusions The AIR Series is a national asynchronous EM curriculum featuring quality blogs and podcasts. It uses a national expert panel and novel scoring instrument to peer review web-based educational resources.

  11. Identify-Isolate-Inform: A Tool for Initial Detection and Management of Zika Virus Patients in the Emergency Department.

    PubMed

    Koenig, Kristi L; Almadhyan, Abdulmajeed; Burns, Michael J

    2016-05-01

    First isolated in 1947 from a monkey in the Zika forest in Uganda, and from mosquitoes in the same forest the following year, Zika virus has gained international attention due to concerns for infection in pregnant women potentially causing fetal microcephaly. More than one million people have been infected since the appearance of the virus in Brazil in 2015. Approximately 80% of infected patients are asymptomatic. An association with microcephaly and other birth defects as well as Guillain-Barre Syndrome has led to a World Health Organization declaration of Zika virus as a Public Health Emergency of International Concern in February 2016. Zika virus is a vector-borne disease transmitted primarily by the Aedes aegypti mosquito. Male to female sexual transmission has been reported and there is potential for transmission via blood transfusions. After an incubation period of 2-7 days, symptomatic patients develop rapid onset fever, maculopapular rash, arthralgia, and conjunctivitis, often associated with headache and myalgias. Emergency department (ED) personnel must be prepared to address concerns from patients presenting with symptoms consistent with acute Zika virus infection, especially those who are pregnant or planning travel to Zika-endemic regions, as well as those women planning to become pregnant and their partners. The identify-isolate-inform (3I) tool, originally conceived for initial detection and management of Ebola virus disease patients in the ED, and later adjusted for measles and Middle East Respiratory Syndrome, can be adapted for real-time use for any emerging infectious disease. This paper reports a modification of the 3I tool for initial detection and management of patients under investigation for Zika virus. Following an assessment of epidemiologic risk, including travel to countries with mosquitoes that transmit Zika virus, patients are further investigated if clinically indicated. If after a rapid evaluation, Zika or other arthropod

  12. Identify-Isolate-Inform: A Tool for Initial Detection and Management of Zika Virus Patients in the Emergency Department

    PubMed Central

    Koenig, Kristi L.; Almadhyan, Abdulmajeed; Burns, Michael J.

    2016-01-01

    First isolated in 1947 from a monkey in the Zika forest in Uganda, and from mosquitoes in the same forest the following year, Zika virus has gained international attention due to concerns for infection in pregnant women potentially causing fetal microcephaly. More than one million people have been infected since the appearance of the virus in Brazil in 2015. Approximately 80% of infected patients are asymptomatic. An association with microcephaly and other birth defects as well as Guillain-Barre Syndrome has led to a World Health Organization declaration of Zika virus as a Public Health Emergency of International Concern in February 2016. Zika virus is a vector-borne disease transmitted primarily by the Aedes aegypti mosquito. Male to female sexual transmission has been reported and there is potential for transmission via blood transfusions. After an incubation period of 2–7 days, symptomatic patients develop rapid onset fever, maculopapular rash, arthralgia, and conjunctivitis, often associated with headache and myalgias. Emergency department (ED) personnel must be prepared to address concerns from patients presenting with symptoms consistent with acute Zika virus infection, especially those who are pregnant or planning travel to Zika-endemic regions, as well as those women planning to become pregnant and their partners. The identify-isolate-inform (3I) tool, originally conceived for initial detection and management of Ebola virus disease patients in the ED, and later adjusted for measles and Middle East Respiratory Syndrome, can be adapted for real-time use for any emerging infectious disease. This paper reports a modification of the 3I tool for initial detection and management of patients under investigation for Zika virus. Following an assessment of epidemiologic risk, including travel to countries with mosquitoes that transmit Zika virus, patients are further investigated if clinically indicated. If after a rapid evaluation, Zika or other arthropod

  13. KLF4 and PCNA identify stages of tumor initiation in a conditional model of cutaneous squamous epithelial neoplasia.

    PubMed

    Huang, Conway C; Liu, Zhaoli; Li, Xingnan; Bailey, Sarah K; Nail, Clinton D; Foster, K Wade; Frost, Andra R; Ruppert, J Michael; Lobo-Ruppert, Susan M

    2005-12-01

    KLF4 is induced upon growth-arrest in vitro and during epithelial maturation in vivo, and is essential for proper cell fate specification of post-mitotic cells. In spite of a normal role in post-mitotic cells, expression is upregulated and constitutive in certain tumor types. KLF4 functions as an oncogene in vitro, and enforced expression in basal cells of mouse skin rapidly induces lesions similar to hyperplasia, dysplasia and squamous cell carcinoma (SCC). Here we used conditional expression to characterize early steps in KLF4-mediated tumor initiation. In contrast to SCC-like lesions that result when using a conditional, keratin 14 promoter-dependent strategy, lower conditional expression achieved using a MMTV promoter induced only epidermal cycling within morphologically normal skin, a process we termed occult cell turnover. Surprisingly, KLF4-induced hyperplastic lesions showed increased transgene-derived mRNA and protein in maturing, PCNA-negative cells, a property of endogenous KLF4. In contrast, hyperplastic lesions induced by GLI1, a control, showed uniform transgene expression. In KLF4-induced dysplasia and SCC the complementarity of KLF4 and PCNA was replaced by concordance of the two proteins. These studies show that KLF4 transcripts are normally suppressed in cycling cells in a promoter-independent fashion, consistent with a post-transcriptional control, and reveal loss of this control in the transition from hyperplasia to dysplasia. Like the mouse tumors, human cutaneous SCCs and adjacent dysplasias frequently showed maturation-independence of KLF4, with co-expression of KLF4 and PCNA. A smaller subset of human SCCs showed complementarity of KLF4 and PCNA, similar to hyperplastic mouse skin. The results identify parallels between a mouse model and human primary tumors, and show that successive increases of KLF4 in the nuclei of basal keratinocytes leads to occult cell turnover followed by hyperplasia, dysplasia, and invasive SCC.

  14. Functional analysis of recently identified mutations in eukaryotic translation initiation factor 2Bɛ (eIF2Bɛ) identified in Chinese patients with vanishing white matter disease.

    PubMed

    Leng, Xuerong; Wu, Ye; Wang, Xuemin; Pan, Yanxia; Wang, Jingmin; Li, Jiao; Du, Li; Dai, Lifang; Wu, Xiru; Proud, Christopher G; Jiang, Yuwu

    2011-04-01

    Vanishing white matter disease (VWM) is the first human hereditary disease known to be caused by defects in initiation of protein synthesis. Gene defects in each of the five subunits of eukaryotic translation initiation factor 2B (eIF2B α-ɛ) are responsible for the disease, although the mechanism of the pathogenesis is not well understood. In our previous study, four novel eIF2Bɛ mutations were found in Chinese patients: p.Asp62Val, p.Cys335Ser, p.Asn376Asp and p.Ser610-Asp613del. Functional analysis was performed on these mutations and the recently reported p.Arg269X. Our data showed that all resulted in a decrease in the guanine nucleotide exchange (GEF) activity of the eIF2B complex. p.Arg269X and p.Ser610-Asp613del mutants displayed the lowest activity, followed by p.Cys335Ser, p.Asn376Asp and p.Asp62Val. p.Arg269X and p.Ser610-Asp613del could not produce stable eIF2Bɛ, leading to almost complete loss-of-function. No evidence was obtained for the three missense mutations in changes in eIF2Bɛ protein level or eIF2BɛSer(540) phosphorylation, and disruption of holocomplex assembly, or binding to eIF2. All patients in our study had the classical phenotype. p.Asp62Val and p.Asn376Asp mutations caused only mildly decreased GEF activity, were probably responsible for relatively mild phenotype in cases of classical VWM.

  15. EBS Radionuclide Transport Abstraction

    SciTech Connect

    R. Schreiner

    2001-06-27

    elements of the TSPA-SR model. The scope of the EBS RT Abstraction also does not include computational or numerical procedures for solving the process-level equations; rather, it identifies the important processes that must then be evaluated with process-level or component-level software using analytical or numerical solutions.

  16. Are all abstracts created equal??

    PubMed

    Weinert, Clarann

    2010-05-01

    The preparation of a strong, convincing abstract is a necessary professional skill and prized art form for nurse scientists and clinical scholars. The power and the role of an abstract are often overlooked. Abstracts are used in a variety of scholarly forums including articles submitted for publication, research proposals, and responses to "calls for abstracts" for presentations at scientific conferences. The purpose of this article is to emphasize the highlights of the "art" rather than the "cookbook" details associated with preparing an abstract. Each of the critical stages of abstract development is explored-planning, drafting, reviewing, peer reviewing, editing, and packaging. Likewise, a few, hopefully helpful, hints on developing the six key elements-background, purpose, sample, methods, results, and implications-of the scientific abstract are given. Polishing, the essential skill of preparing an abstract, takes time and persistence and will pay off in the long run. The well-crafted abstract is an initial step in the process of getting research and scholarly pursuits noticed and accepted.

  17. The Art of Abstracting.

    ERIC Educational Resources Information Center

    Cremmins, Edward T.

    A three-stage analytical reading method for the composition of informative and indicative abstracts by authors and abstractors is presented in this monograph, along with background information on the abstracting process and a discussion of professional considerations in abstracting. An introduction to abstracts and abstracting precedes general…

  18. EBS Radionuclide Transport Abstraction

    SciTech Connect

    J. Prouty

    2006-07-14

    The purpose of this report is to develop and analyze the engineered barrier system (EBS) radionuclide transport abstraction model, consistent with Level I and Level II model validation, as identified in Technical Work Plan for: Near-Field Environment and Transport: Engineered Barrier System: Radionuclide Transport Abstraction Model Report Integration (BSC 2005 [DIRS 173617]). The EBS radionuclide transport abstraction (or EBS RT Abstraction) is the conceptual model used in the total system performance assessment (TSPA) to determine the rate of radionuclide releases from the EBS to the unsaturated zone (UZ). The EBS RT Abstraction conceptual model consists of two main components: a flow model and a transport model. Both models are developed mathematically from first principles in order to show explicitly what assumptions, simplifications, and approximations are incorporated into the models used in the TSPA. The flow model defines the pathways for water flow in the EBS and specifies how the flow rate is computed in each pathway. Input to this model includes the seepage flux into a drift. The seepage flux is potentially split by the drip shield, with some (or all) of the flux being diverted by the drip shield and some passing through breaches in the drip shield that might result from corrosion or seismic damage. The flux through drip shield breaches is potentially split by the waste package, with some (or all) of the flux being diverted by the waste package and some passing through waste package breaches that might result from corrosion or seismic damage. Neither the drip shield nor the waste package survives an igneous intrusion, so the flux splitting submodel is not used in the igneous scenario class. The flow model is validated in an independent model validation technical review. The drip shield and waste package flux splitting algorithms are developed and validated using experimental data. The transport model considers advective transport and diffusive transport

  19. Identifying intrinsic and extrinsic determinants that regulate internal initiation of translation mediated by the FMR1 5' leader

    PubMed Central

    Dobson, Tara; Kube, Erika; Timmerman, Stephanie; Krushel, Les A

    2008-01-01

    Background Regulating synthesis of the Fragile X gene (FMR1) product, FMRP alters neural plasticity potentially through its role in the microRNA pathway. Cap-dependent translation of the FMR1 mRNA, a process requiring ribosomal scanning through the 5' leader, is likely impeded by the extensive secondary structure generated by the high guanosine/cytosine nucleotide content including the CGG triplet nucleotide repeats in the 5' leader. An alternative mechanism to initiate translation – internal initiation often utilizes secondary structure to recruit the translational machinery. Consequently, studies were undertaken to confirm and extend a previous observation that the FMR1 5' leader contains an internal ribosomal entry site (IRES). Results Cellular transfection of a dicistronic DNA construct containing the FMR1 5' leader inserted into the intercistronic region yielded significant translation of the second cistron, but the FMR1 5' leader was also found to contain a cryptic promoter possibly confounding interpretation of these results. However, transfection of dicistronic and monocistronic RNA ex vivo or in vitro confirmed that the FMR1 5' leader contains an IRES. Moreover, inhibiting cap-dependent translation ex vivo did not affect the expression level of endogenous FMRP indicating a role for IRES-dependent translation of FMR1 mRNA. Analysis of the FMR1 5' leader revealed that the CGG repeats and the 5' end of the leader were vital for internal initiation. Functionally, exposure to potassium chloride or intracellular acidification and addition of polyinosinic:polycytidylic acid as mimics of neural activity and double stranded RNA, respectively, differentially affected FMR1 IRES activity. Conclusion Our results indicate that multiple stimuli influence IRES-dependent translation of the FMR1 mRNA and suggest a functional role for the CGG nucleotide repeats. PMID:18922172

  20. "In the Middle of Difficulty Lies Opportunity"--Using a Case Study to Identify Critical Success Factors Contributing to the Initiation of International Collaborative Projects

    ERIC Educational Resources Information Center

    Johnson, Ian M.

    2005-01-01

    This paper identifies factors that contribute to the successful initiation of international collaborative projects intended to support the development of education for librarianship and information sciences. It discusses the widespread failure to analyse the Critical Success Factors in international collaborative projects and proposes a case study…

  1. Identify-Isolate-Inform: A Tool for Initial Detection and Management of Measles Patients in the Emergency Department

    PubMed Central

    Koenig, Kristi L.; Alassaf, Wajdan; Burns, Michael J.

    2015-01-01

    Measles (rubeola) is a highly contagious airborne disease that was declared eliminated in the U.S. in the year 2000. Only sporadic U.S. cases and minor outbreaks occurred until the larger outbreak beginning in 2014 that has become a public health emergency. The “Identify-Isolate-Inform” tool will assist emergency physicians to be better prepared to detect and manage measles patients presenting to the emergency department. Measles typically presents with a prodrome of high fever, and cough/coryza/conjunctivitis, sometimes accompanied by the pathognomonic Koplik spots. Two to four days later, an erythematous maculopapular rash begins on the face and spreads down the body. Suspect patients must be immediately isolated with airborne precautions while awaiting laboratory confirmation of disease. Emergency physicians must rapidly inform the local public health department and hospital infection control personnel of suspected measles cases. PMID:25834659

  2. Identify-isolate-inform: a tool for initial detection and management of measles patients in the emergency department.

    PubMed

    Koenig, Kristi L; Alassaf, Wajdan; Burns, Michael J

    2015-03-01

    Measles (rubeola) is a highly contagious airborne disease that was declared eliminated in the U.S. in the year 2000. Only sporadic U.S. cases and minor outbreaks occurred until the larger outbreak beginning in 2014 that has become a public health emergency. The "Identify-Isolate-Inform" tool will assist emergency physicians to be better prepared to detect and manage measles patients presenting to the emergency department. Measles typically presents with a prodrome of high fever, and cough/coryza/conjunctivitis, sometimes accompanied by the pathognomonic Koplik spots. Two to four days later, an erythematous maculopapular rash begins on the face and spreads down the body. Suspect patients must be immediately isolated with airborne precautions while awaiting laboratory confirmation of disease. Emergency physicians must rapidly inform the local public health department and hospital infection control personnel of suspected measles cases.

  3. Abstraction and Consolidation

    ERIC Educational Resources Information Center

    Monaghan, John; Ozmantar, Mehmet Fatih

    2006-01-01

    The framework for this paper is a recently developed theory of abstraction in context. The paper reports on data collected from one student working on tasks concerned with absolute value functions. It examines the relationship between mathematical constructions and abstractions. It argues that an abstraction is a consolidated construction that can…

  4. EBS Radionuclide Transport Abstraction

    SciTech Connect

    J.D. Schreiber

    2005-08-25

    The purpose of this report is to develop and analyze the engineered barrier system (EBS) radionuclide transport abstraction model, consistent with Level I and Level II model validation, as identified in ''Technical Work Plan for: Near-Field Environment and Transport: Engineered Barrier System: Radionuclide Transport Abstraction Model Report Integration'' (BSC 2005 [DIRS 173617]). The EBS radionuclide transport abstraction (or EBS RT Abstraction) is the conceptual model used in the total system performance assessment for the license application (TSPA-LA) to determine the rate of radionuclide releases from the EBS to the unsaturated zone (UZ). The EBS RT Abstraction conceptual model consists of two main components: a flow model and a transport model. Both models are developed mathematically from first principles in order to show explicitly what assumptions, simplifications, and approximations are incorporated into the models used in the TSPA-LA. The flow model defines the pathways for water flow in the EBS and specifies how the flow rate is computed in each pathway. Input to this model includes the seepage flux into a drift. The seepage flux is potentially split by the drip shield, with some (or all) of the flux being diverted by the drip shield and some passing through breaches in the drip shield that might result from corrosion or seismic damage. The flux through drip shield breaches is potentially split by the waste package, with some (or all) of the flux being diverted by the waste package and some passing through waste package breaches that might result from corrosion or seismic damage. Neither the drip shield nor the waste package survives an igneous intrusion, so the flux splitting submodel is not used in the igneous scenario class. The flow model is validated in an independent model validation technical review. The drip shield and waste package flux splitting algorithms are developed and validated using experimental data. The transport model considers

  5. Abstraction in mathematics.

    PubMed Central

    Ferrari, Pier Luigi

    2003-01-01

    Some current interpretations of abstraction in mathematical settings are examined from different perspectives, including history and learning. It is argued that abstraction is a complex concept and that it cannot be reduced to generalization or decontextualization only. In particular, the links between abstraction processes and the emergence of new objects are shown. The role that representations have in abstraction is discussed, taking into account both the historical and the educational perspectives. As languages play a major role in mathematics, some ideas from functional linguistics are applied to explain to what extent mathematical notations are to be considered abstract. Finally, abstraction is examined from the perspective of mathematics education, to show that the teaching ideas resulting from one-dimensional interpretations of abstraction have proved utterly unsuccessful. PMID:12903658

  6. Stellar Presentations (Abstract)

    NASA Astrophysics Data System (ADS)

    Young, D.

    2015-12-01

    (Abstract only) The AAVSO is in the process of expanding its education, outreach and speakers bureau program. powerpoint presentations prepared for specific target audiences such as AAVSO members, educators, students, the general public, and Science Olympiad teams, coaches, event supervisors, and state directors will be available online for members to use. The presentations range from specific and general content relating to stellar evolution and variable stars to specific activities for a workshop environment. A presentation—even with a general topic—that works for high school students will not work for educators, Science Olympiad teams, or the general public. Each audience is unique and requires a different approach. The current environment necessitates presentations that are captivating for a younger generation that is embedded in a highly visual and sound-bite world of social media, twitter and U-Tube, and mobile devices. For educators, presentations and workshops for themselves and their students must support the Next Generation Science Standards (NGSS), the Common Core Content Standards, and the Science Technology, Engineering and Mathematics (STEM) initiative. Current best practices for developing relevant and engaging powerpoint presentations to deliver information to a variety of targeted audiences will be presented along with several examples.

  7. oriGNAI3: a narrow zone of preferential replication initiation in mammalian cells identified by 2D gel and competitive PCR replicon mapping techniques.

    PubMed Central

    Toledo, F; Baron, B; Fernandez, M A; Lachagès, A M; Mayau, V; Buttin, G; Debatisse, M

    1998-01-01

    The nature of mammalian origins of DNA replication remains controversial and this is primarily because two-dimensional gel replicon mapping techniques have identified broad zones of replication initiation whereas several other techniques, such as quantitative PCR, have disclosed more discrete sites of initiation at the same chromosomal loci. In this report we analyze the replication of an amplified genomic region encompassing the 3'-end of the GNAI3 gene, the entire GNAT2 gene and the intergenic region between them in exponentially growing Chinese hamster fibroblasts. These cells express GNAI3 but not GNAT2 . The replication pattern was first analyzed by two-dimensional neutral-alkaline gel electrophoresis. Surprisingly, the results revealed a small preferential zone of replication initiation, of at most 1.7 kb, located in a limited part of the GNAI3 - GNAT2 intergenic region. Mapping of this initiation zone was then confirmed by quantitative PCR. The agreement between the two techniques exploited here strengthens the hypothesis that preferred sites of replication initiation do exist in mammalian genomes. PMID:9580680

  8. Abstract and keywords.

    PubMed

    Peh, W C G; Ng, K H

    2008-09-01

    The abstract of a scientific paper represents a concise, accurate and factual mini-version of the paper contents. Abstract format may vary according to the individual journal. For original articles, a structured abstract usually consists of the following headings: aims (or objectives), materials and methods, results and conclusion. A few keywords that capture the main topics of the paper help indexing in the medical literature.

  9. Automated Supernova Discovery (Abstract)

    NASA Astrophysics Data System (ADS)

    Post, R. S.

    2015-12-01

    (Abstract only) We are developing a system of robotic telescopes for automatic recognition of Supernovas as well as other transient events in collaboration with the Puckett Supernova Search Team. At the SAS2014 meeting, the discovery program, SNARE, was first described. Since then, it has been continuously improved to handle searches under a wide variety of atmospheric conditions. Currently, two telescopes are used to build a reference library while searching for PSN with a partial library. Since data is taken every night without clouds, we must deal with varying atmospheric and high background illumination from the moon. Software is configured to identify a PSN, reshoot for verification with options to change the run plan to acquire photometric or spectrographic data. The telescopes are 24-inch CDK24, with Alta U230 cameras, one in CA and one in NM. Images and run plans are sent between sites so the CA telescope can search while photometry is done in NM. Our goal is to find bright PSNs with magnitude 17.5 or less which is the limit of our planned spectroscopy. We present results from our first automated PSN discoveries and plans for PSN data acquisition.

  10. Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS

    PubMed Central

    Sun, Shuying; Sun, Ying; Ling, Shuo-Chien; Ferraiuolo, Laura; McAlonis-Downes, Melissa; Zou, Yiyang; Drenner, Kevin; Wang, Yin; Ditsworth, Dara; Tokunaga, Seiya; Kopelevich, Alex; Kaspar, Brian K.; Lagier-Tourenne, Clotilde; Cleveland, Don W.

    2015-01-01

    Ubiquitous expression of amyotrophic lateral sclerosis (ALS)-causing mutations in superoxide dismutase 1 (SOD1) provokes noncell autonomous paralytic disease. By combining ribosome affinity purification and high-throughput sequencing, a cascade of mutant SOD1-dependent, cell type-specific changes are now identified. Initial mutant-dependent damage is restricted to motor neurons and includes synapse and metabolic abnormalities, endoplasmic reticulum (ER) stress, and selective activation of the PRKR-like ER kinase (PERK) arm of the unfolded protein response. PERK activation correlates with what we identify as a naturally low level of ER chaperones in motor neurons. Early changes in astrocytes occur in genes that are involved in inflammation and metabolism and are targets of the peroxisome proliferator-activated receptor and liver X receptor transcription factors. Dysregulation of myelination and lipid signaling pathways and activation of ETS transcription factors occur in oligodendrocytes only after disease initiation. Thus, pathogenesis involves a temporal cascade of cell type-selective damage initiating in motor neurons, with subsequent damage within glia driving disease propagation. PMID:26621731

  11. Yeast Genome-Wide Expression Analysis Identifies a Strong Ergosterol and Oxidative Stress Response during the Initial Stages of an Industrial Lager Fermentation

    PubMed Central

    Higgins, Vincent J.; Beckhouse, Anthony G.; Oliver, Anthony D.; Rogers, Peter J.; Dawes, Ian W.

    2003-01-01

    Genome-wide expression analysis of an industrial strain of Saccharomyces cerevisiae during the initial stages of an industrial lager fermentation identified a strong response from genes involved in the biosynthesis of ergosterol and oxidative stress protection. The induction of the ERG genes was confirmed by Northern analysis and was found to be complemented by a rapid accumulation of ergosterol over the initial 6-h fermentation period. From a test of the metabolic activity of deletion mutants in the ergosterol biosynthesis pathway, it was found that ergosterol is an important factor in restoring the fermentative capacity of the cell after storage. Additionally, similar ERG10 and TRR1 gene expression patterns over the initial 24-h fermentation period highlighted a possible interaction between ergosterol biosynthesis and the oxidative stress response. Further analysis showed that erg mutants producing altered sterols were highly sensitive to oxidative stress-generating compounds. Here we show that genome-wide expression analysis can be used in the commercial environment and was successful in identifying environmental conditions that are important in industrial yeast fermentation. PMID:12902271

  12. Initial and secondary oxidation products on the Si(111)-(7 × 7) surface identified by atomic force microscopy and first principles calculations

    SciTech Connect

    Onoda, Jo Sugimoto, Yoshiaki; Ondráček, Martin; Jelínek, Pavel

    2014-03-31

    We investigate the initial and secondary oxidation products on the Si(111)-(7 × 7) surface at room-temperature using atomic force microscopy (AFM) and density functional theory calculations. At the initial oxidation stages, we find that there are two types of bright spots in AFM images. One of them is identified as a Si adatom with one O atom inserted into one of the backbonds, while the other is ascribed to a Si adatom with two inserted O atoms. We observe that the latter one turns into the secondary oxidation product by a further coming O{sub 2} molecule, which appears as a more protruded bright spot. The atomic configuration of this product is identified as Si adatom whose top and all three backbonds make bonds with O atoms. The appearances of initial and secondary oxidation products are imaged as bright and dark sites by scanning tunneling microscopy, respectively. It is revealed that AFM gives us the topographic information close to the real atomic corrugation of adsorbed structures on the semiconductor surfaces.

  13. Technical Abstracts, 1988

    SciTech Connect

    Kotowski, M.

    1989-05-01

    This document is a compilation of the abstracts from unclassified documents published by Mechanical Engineering at Lawrence Livermore National Laboratory (LLNL) during the calendar year 1988. Many abstracts summarize work completed and published in report form. These are UCRL-90,000 and 100,000 series documents, which include the full text of articles to be published in journals and of papers to be presented at meetings, and UCID reports, which are informal documents. Not all UCIDs contain abstracts: short summaries were generated when abstracts were not included. Technical Abstracts also provides brief descriptions of those documents assigned to the MISC (miscellaneous) category. These are generally viewgraphs or photographs presented at meetings. The abstracts cover the broad range of technologies within Mechanical Engineering and are grouped by the principal author's division. An eighth category is devoted to abstracts presented at the CUBE symposium sponsored jointly by LLNL, Los Alamos National Laboratory, and Sandia Laboratories. Within these areas, abstracts are listed numerically. An author index and title index are provided at the back of the book for cross referencing. The publications listed may be obtained by contacting LLNL's TID library or the National Technical Information Service, US Department of Commerce, 5285 Port Royal Road, Springfield, VA 22161. Further information may be obtained by contacting the author directly or the persons listed in the introduction of each subject area.

  14. Paper Abstract Animals

    ERIC Educational Resources Information Center

    Sutley, Jane

    2010-01-01

    Abstraction is, in effect, a simplification and reduction of shapes with an absence of detail designed to comprise the essence of the more naturalistic images being depicted. Without even intending to, young children consistently create interesting, and sometimes beautiful, abstract compositions. A child's creations, moreover, will always seem to…

  15. Leadership Abstracts, Volume 10.

    ERIC Educational Resources Information Center

    Milliron, Mark D., Ed.

    1997-01-01

    The abstracts in this series provide brief discussions of issues related to leadership, administration, professional development, technology, and education in community colleges. Volume 10 for 1997 contains the following 12 abstracts: (1) "On Community College Renewal" (Nathan L. Hodges and Mark D. Milliron); (2) "The Community College Niche in a…

  16. Is It Really Abstract?

    ERIC Educational Resources Information Center

    Kernan, Christine

    2011-01-01

    For this author, one of the most enjoyable aspects of teaching elementary art is the willingness of students to embrace the different styles of art introduced to them. In this article, she describes a project that allows upper-elementary students to learn about abstract art and the lives of some of the master abstract artists, implement the idea…

  17. Designing for Mathematical Abstraction

    ERIC Educational Resources Information Center

    Pratt, Dave; Noss, Richard

    2010-01-01

    Our focus is on the design of systems (pedagogical, technical, social) that encourage mathematical abstraction, a process we refer to as "designing for abstraction." In this paper, we draw on detailed design experiments from our research on children's understanding about chance and distribution to re-present this work as a case study in designing…

  18. Leadership Abstracts, 1996.

    ERIC Educational Resources Information Center

    Johnson, Larry, Ed.

    1996-01-01

    The abstracts in this series provide two-page discussions of issues related to leadership, administration, professional development, technology, and education in community colleges. Volume 9 for 1996 includes the following 12 abstracts: (1) "Tech-Prep + School-To-Work: Working Together To Foster Educational Reform," (Roderick F. Beaumont); (2)…

  19. Organizational Communication Abstracts--1975.

    ERIC Educational Resources Information Center

    Falcione, Raymond L.; And Others

    This document includes nearly 700 brief abstracts of works published in 1975 that are relevant to the field of organizational communication. The introduction presents a rationale for the project, a review of research methods developed by the authors for the preparation of abstracts, a statement of limitations as to the completeness of the coverage…

  20. Abstract Datatypes in PVS

    NASA Technical Reports Server (NTRS)

    Owre, Sam; Shankar, Natarajan

    1997-01-01

    PVS (Prototype Verification System) is a general-purpose environment for developing specifications and proofs. This document deals primarily with the abstract datatype mechanism in PVS which generates theories containing axioms and definitions for a class of recursive datatypes. The concepts underlying the abstract datatype mechanism are illustrated using ordered binary trees as an example. Binary trees are described by a PVS abstract datatype that is parametric in its value type. The type of ordered binary trees is then presented as a subtype of binary trees where the ordering relation is also taken as a parameter. We define the operations of inserting an element into, and searching for an element in an ordered binary tree; the bulk of the report is devoted to PVS proofs of some useful properties of these operations. These proofs illustrate various approaches to proving properties of abstract datatype operations. They also describe the built-in capabilities of the PVS proof checker for simplifying abstract datatype expressions.

  1. Modelling abstraction licensing strategies ahead of the UK's water abstraction licensing reform

    NASA Astrophysics Data System (ADS)

    Klaar, M. J.

    2012-12-01

    Within England and Wales, river water abstractions are licensed and regulated by the Environment Agency (EA), who uses compliance with the Environmental Flow Indicator (EFI) to ascertain where abstraction may cause undesirable effects on river habitats and species. The EFI is a percentage deviation from natural flow represented using a flow duration curve. The allowable percentage deviation changes with different flows, and also changes depending on an assessment of the sensitivity of the river to changes in flow (Table 1). Within UK abstraction licensing, resource availability is expressed as a surplus or deficit of water resources in relation to the EFI, and utilises the concept of 'hands-off-flows' (HOFs) at the specified flow statistics detailed in Table 1. Use of a HOF system enables abstraction to cease at set flows, but also enables abstraction to occur at periods of time when more water is available. Compliance at low flows (Q95) is used by the EA to determine the hydrological classification and compliance with the Water Framework Directive (WFD) for identifying waterbodies where flow may be causing or contributing to a failure in good ecological status (GES; Table 2). This compliance assessment shows where the scenario flows are below the EFI and by how much, to help target measures for further investigation and assessment. Currently, the EA is reviewing the EFI methodology in order to assess whether or not it can be used within the reformed water abstraction licensing system which is being planned by the Department for Environment, Food and Rural Affairs (DEFRA) to ensure the licensing system is resilient to the challenges of climate change and population growth, while allowing abstractors to meet their water needs efficiently, and better protect the environment. In order to assess the robustness of the EFI, a simple model has been created which allows a number of abstraction, flow and licensing scenarios to be run to determine WFD compliance using the

  2. Automatic Abstraction in Planning

    NASA Technical Reports Server (NTRS)

    Christensen, J.

    1991-01-01

    Traditionally, abstraction in planning has been accomplished by either state abstraction or operator abstraction, neither of which has been fully automatic. We present a new method, predicate relaxation, for automatically performing state abstraction. PABLO, a nonlinear hierarchical planner, implements predicate relaxation. Theoretical, as well as empirical results are presented which demonstrate the potential advantages of using predicate relaxation in planning. We also present a new definition of hierarchical operators that allows us to guarantee a limited form of completeness. This new definition is shown to be, in some ways, more flexible than previous definitions of hierarchical operators. Finally, a Classical Truth Criterion is presented that is proven to be sound and complete for a planning formalism that is general enough to include most classical planning formalisms that are based on the STRIPS assumption.

  3. Searching Sociological Abstracts.

    ERIC Educational Resources Information Center

    Kerbel, Sandra Sandor

    1981-01-01

    Describes the scope, content, and retrieval characteristics of Sociological Abstracts, an online database of literature in the social sciences. Sample searches are displayed, and the strengths and weaknesses of the database are summarized. (FM)

  4. Conference Abstracts: AEDS '82.

    ERIC Educational Resources Information Center

    Journal of Computers in Mathematics and Science Teaching, 1982

    1982-01-01

    Abstracts from nine selected papers presented at the 1982 Association for Educational Data Systems (AEDS) conference are provided. Copies of conference proceedings may be obtained for fifteen dollars from the Association. (MP)

  5. Abstracts of SIG Sessions.

    ERIC Educational Resources Information Center

    Proceedings of the ASIS Annual Meeting, 1997

    1997-01-01

    Presents abstracts of SIG Sessions. Highlights include digital collections; information retrieval methods; public interest/fair use; classification and indexing; electronic publication; funding; globalization; information technology projects; interface design; networking in developing countries; metadata; multilingual databases; networked…

  6. Abstracts of contributed papers

    SciTech Connect

    Not Available

    1994-08-01

    This volume contains 571 abstracts of contributed papers to be presented during the Twelfth US National Congress of Applied Mechanics. Abstracts are arranged in the order in which they fall in the program -- the main sessions are listed chronologically in the Table of Contents. The Author Index is in alphabetical order and lists each paper number (matching the schedule in the Final Program) with its corresponding page number in the book.

  7. Consumer Participation in Quality Improvements for Chronic Disease Care: Development and Evaluation of an Interactive Patient-Centered Survey to Identify Preferred Service Initiatives

    PubMed Central

    Paul, Christine L; Bryant, Jamie; Roos, Ian A; Henskens, Frans A; Paul, David J

    2014-01-01

    Background With increasing attention given to the quality of chronic disease care, a measurement approach that empowers consumers to participate in improving quality of care and enables health services to systematically introduce patient-centered initiatives is needed. A Web-based survey with complex adaptive questioning and interactive survey items would allow consumers to easily identify and prioritize detailed service initiatives. Objective The aim was to develop and test a Web-based survey capable of identifying and prioritizing patient-centered initiatives in chronic disease outpatient services. Testing included (1) test-retest reliability, (2) patient-perceived acceptability of the survey content and delivery mode, and (3) average completion time, completion rates, and Flesch-Kincaid reading score. Methods In Phase I, the Web-based Consumer Preferences Survey was developed based on a structured literature review and iterative feedback from expert groups of service providers and consumers. The touchscreen survey contained 23 general initiatives, 110 specific initiatives available through adaptive questioning, and a relative prioritization exercise. In Phase II, a pilot study was conducted within 4 outpatient clinics to evaluate the reliability properties, patient-perceived acceptability, and feasibility of the survey. Eligible participants were approached to complete the survey while waiting for an appointment or receiving intravenous therapy. The age and gender of nonconsenters was estimated to ascertain consent bias. Participants with a subsequent appointment within 14 days were asked to complete the survey for a second time. Results A total of 741 of 1042 individuals consented to participate (71.11% consent), 529 of 741 completed all survey content (78.9% completion), and 39 of 68 completed the test-retest component. Substantial or moderate reliability (Cohen’s kappa>0.4) was reported for 16 of 20 general initiatives with observed percentage agreement

  8. Abstraction-based temporal data retrieval for a Clinical Data Repository.

    PubMed

    Post, Andrew R; Sovarel, Ana N; Harrison, James H

    2007-10-11

    Disease and patient care processes often create characteristic states, trends, and temporal patterns in clinical events and observations, called temporal abstractions. Identifying patient populations who share similar abstractions may be useful for clinical research, outcomes studies, and quality assurance. In these settings, abstractions may be specific to a query, and thus allowing the specification of abstractions directly in the query would be desirable. We propose a query language for specifying and retrieving clinical data sets that allows specifying abstractions directly, and automatically selects data for retrieval based on the presence of abstractions inferred from the data. We describe the language and a prototype implementation, demonstrate its features with two queries constructed in response to clinical researcher-initiated data requests submitted to our institution's Clinical Data Repository, and report preliminary results from an evaluation of the implementation's performance.

  9. Metacognition and abstract reasoning.

    PubMed

    Markovits, Henry; Thompson, Valerie A; Brisson, Janie

    2015-05-01

    The nature of people's meta-representations of deductive reasoning is critical to understanding how people control their own reasoning processes. We conducted two studies to examine whether people have a metacognitive representation of abstract validity and whether familiarity alone acts as a separate metacognitive cue. In Study 1, participants were asked to make a series of (1) abstract conditional inferences, (2) concrete conditional inferences with premises having many potential alternative antecedents and thus specifically conducive to the production of responses consistent with conditional logic, or (3) concrete problems with premises having relatively few potential alternative antecedents. Participants gave confidence ratings after each inference. Results show that confidence ratings were positively correlated with logical performance on abstract problems and concrete problems with many potential alternatives, but not with concrete problems with content less conducive to normative responses. Confidence ratings were higher with few alternatives than for abstract content. Study 2 used a generation of contrary-to-fact alternatives task to improve levels of abstract logical performance. The resulting increase in logical performance was mirrored by increases in mean confidence ratings. Results provide evidence for a metacognitive representation based on logical validity, and show that familiarity acts as a separate metacognitive cue.

  10. Parameter identifiability and Extended Multiple Studies Analysis of a compartmental model for human vitamin A kinetics: fixing fractional transfer coefficients for the initial steps in the absorptive process.

    PubMed

    Park, Hyunjin; Green, Michael H

    2014-03-28

    In the existing compartmental models of human vitamin A metabolism, parameters related to the absorption of the isotopic oral dose have not been well identified. We hypothesised that fixing some poorly identified parameters related to vitamin A absorption would improve parameter identifiability and add statistical certainty to such models. In the present study, data for serum vitamin A kinetics in nine subjects given [2H8]retinyl acetate orally and a model with absorption fixed at 75 % were used to test this hypothesis. In addition to absorption efficiency, we fixed two other fractional transfer coefficients: one representing the initial processing of the ingested dose and the other representing the direct secretion of retinol bound to retinol-binding protein (RBP) from enterocytes into the plasma. The Windows version of Simulation, Analysis and Modeling software (WinSAAM) was used to fit serum tracer data v. time for each subject. Then, a population model was generated by WinSAAM's Extended Multiple Studies Analysis. All the parameters had fractional standard deviations < 0·5, and none of the pairs of parameters had a correlation coefficient >0·8 (accepted criteria for well-identified parameters). Similar to the values predicted by the original model, total traced mass for retinol was 1160 (sd 468) μmol, and the time for retinol to appear in the plasma bound to RBP was 31·3 (sd 4·4) h. In conclusion, we suggest that this approach holds promise for advancing compartmental modelling of vitamin A kinetics in humans when the dose must be administered orally.

  11. Distal Spike Initiation Zone Location Estimation by Morphological Simulation of Ionic Current Filtering Demonstrated in a Novel Model of an Identified Drosophila Motoneuron

    PubMed Central

    Günay, Cengiz; Sieling, Fred H.; Dharmar, Logesh; Lin, Wei-Hsiang; Wolfram, Verena; Marley, Richard

    2015-01-01

    Studying ion channel currents generated distally from the recording site is difficult because of artifacts caused by poor space clamp and membrane filtering. A computational model can quantify artifact parameters for correction by simulating the currents only if their exact anatomical location is known. We propose that the same artifacts that confound current recordings can help pinpoint the source of those currents by providing a signature of the neuron’s morphology. This method can improve the recording quality of currents initiated at the spike initiation zone (SIZ) that are often distal to the soma in invertebrate neurons. Drosophila being a valuable tool for characterizing ion currents, we estimated the SIZ location and quantified artifacts in an identified motoneuron, aCC/MN1-Ib, by constructing a novel multicompartmental model. Initial simulation of the measured biophysical channel properties in an isopotential Hodgkin-Huxley type neuron model partially replicated firing characteristics. Adding a second distal compartment, which contained spike-generating Na+ and K+ currents, was sufficient to simulate aCC’s in vivo activity signature. Matching this signature using a reconstructed morphology predicted that the SIZ is on aCC’s primary axon, 70 μm after the most distal dendritic branching point. From SIZ to soma, we observed and quantified selective morphological filtering of fast activating currents. Non-inactivating K+ currents are filtered ∼3 times less and despite their large magnitude at the soma they could be as distal as Na+ currents. The peak of transient component (NaT) of the voltage-activated Na+ current is also filtered more than the magnitude of slower persistent component (NaP), which can contribute to seizures. The corrected NaP/NaT ratio explains the previously observed discrepancy when the same channel is expressed in different cells. In summary, we used an in vivo signature to estimate ion channel location and recording artifacts

  12. An integrated genomic approach identifies that the PI3K/AKT/FOXO pathway is involved in breast cancer tumor initiation.

    PubMed

    Smit, Linda; Berns, Katrien; Spence, Katherine; Ryder, W David; Zeps, Nik; Madiredjo, Mandy; Beijersbergen, Roderick; Bernards, René; Clarke, Robert B

    2016-01-19

    Therapy resistance is one of the major impediments to successful cancer treatment. In breast cancer, a small subpopulation of cells with stem cell features, named breast cancer stem cells (BCSC), is responsible for metastasis and recurrence of the tumor. BCSC have the unique ability to grow under non-adherent conditions in "mammospheres". To prevent breast cancer recurrence and metastasis it will be crucial to eradicate BCSC.We used shRNA genetic screening to identify genes that upon knockdown enhance mammosphere formation in breast cancer cells. By integration of these results with gene expression profiles of mammospheres and NOTCH-activated cells, we identified FOXO3A. Modulation of FOXO3A activity results in a change in mammosphere formation, expression of mammary stem cell markers and breast cancer initiating potential. Importantly, lack of FOXO3A expression in breast cancer patients is associated with increased recurrence rate. Our findings provide evidence for a role for FOXO3A downstream of NOTCH and AKT that may have implications for therapies targeting BCSCs.

  13. An integrated genomic approach identifies that the PI3K/AKT/FOXO pathway is involved in breast cancer tumor initiation

    PubMed Central

    Smit, Linda; Berns, Katrien; Spence, Katherine; Ryder, W. David; Zeps, Nik; Madiredjo, Mandy; Beijersbergen, Roderick; Bernards, René; Clarke, Robert B.

    2016-01-01

    Therapy resistance is one of the major impediments to successful cancer treatment. In breast cancer, a small subpopulation of cells with stem cell features, named breast cancer stem cells (BCSC), is responsible for metastasis and recurrence of the tumor. BCSC have the unique ability to grow under non-adherent conditions in “mammospheres”. To prevent breast cancer recurrence and metastasis it will be crucial to eradicate BCSC. We used shRNA genetic screening to identify genes that upon knockdown enhance mammosphere formation in breast cancer cells. By integration of these results with gene expression profiles of mammospheres and NOTCH-activated cells, we identified FOXO3A. Modulation of FOXO3A activity results in a change in mammosphere formation, expression of mammary stem cell markers and breast cancer initiating potential. Importantly, lack of FOXO3A expression in breast cancer patients is associated with increased recurrence rate. Our findings provide evidence for a role for FOXO3A downstream of NOTCH and AKT that may have implications for therapies targeting BCSCs. PMID:26595803

  14. Leadership Abstracts, 2001.

    ERIC Educational Resources Information Center

    Wilson, Cynthia, Ed.

    2001-01-01

    This is volume 14 of Leadership Abstracts, a newsletter published by the League for Innovation (California). Issue 1 of February 2001, "Developmental Education: A Policy Primer," discusses developmental programs in the community college. According to the article, community college trustees and presidents would serve their constituents well by…

  15. Abstract Film and Beyond.

    ERIC Educational Resources Information Center

    Le Grice, Malcolm

    A theoretical and historical account of the main preoccupations of makers of abstract films is presented in this book. The book's scope includes discussion of nonrepresentational forms as well as examination of experiments in the manipulation of time in films. The ten chapters discuss the following topics: art and cinematography, the first…

  16. Leadership Abstracts, 1993.

    ERIC Educational Resources Information Center

    Doucette, Don, Ed.

    1993-01-01

    This document includes 10 issues of Leadership Abstracts (volume 6, 1993), a newsletter published by the League for Innovation in the Community College (California). The featured articles are: (1) "Reinventing Government" by David T. Osborne; (2) "Community College Workforce Training Programs: Expanding the Mission to Meet Critical Needs" by…

  17. Leadership Abstracts, 1999.

    ERIC Educational Resources Information Center

    Leadership Abstracts, 1999

    1999-01-01

    This document contains five Leadership Abstracts publications published February-December 1999. The article, "Teaching the Teachers: Meeting the National Teacher Preparation Challenge," authored by George R. Boggs and Sadie Bragg, examines the community college role and makes recommendations and a call to action for teacher education.…

  18. Computers in Abstract Algebra

    ERIC Educational Resources Information Center

    Nwabueze, Kenneth K.

    2004-01-01

    The current emphasis on flexible modes of mathematics delivery involving new information and communication technology (ICT) at the university level is perhaps a reaction to the recent change in the objectives of education. Abstract algebra seems to be one area of mathematics virtually crying out for computer instructional support because of the…

  19. 2002 NASPSA Conference Abstracts.

    ERIC Educational Resources Information Center

    Journal of Sport & Exercise Psychology, 2002

    2002-01-01

    Contains abstracts from the 2002 conference of the North American Society for the Psychology of Sport and Physical Activity. The publication is divided into three sections: the preconference workshop, "Effective Teaching Methods in the Classroom;" symposia (motor development, motor learning and control, and sport psychology); and free…

  20. Reasoning abstractly about resources

    NASA Technical Reports Server (NTRS)

    Clement, B.; Barrett, A.

    2001-01-01

    r describes a way to schedule high level activities before distributing them across multiple rovers in order to coordinate the resultant use of shared resources regardless of how each rover decides how to perform its activities. We present an algorithm for summarizing the metric resource requirements of an abstract activity based n the resource usages of its potential refinements.

  1. Conference Abstracts: AEDS '84.

    ERIC Educational Resources Information Center

    Baird, William E.

    1985-01-01

    The Association of Educational Data Systems (AEDS) conference included 102 presentations. Abstracts of seven of these presentations are provided. Topic areas considered include LOGO, teaching probability through a computer game, writing effective computer assisted instructional materials, computer literacy, research on instructional…

  2. Leadership Abstracts, 2002.

    ERIC Educational Resources Information Center

    Wilson, Cynthia, Ed.; Milliron, Mark David, Ed.

    2002-01-01

    This 2002 volume of Leadership Abstracts contains issue numbers 1-12. Articles include: (1) "Skills Certification and Workforce Development: Partnering with Industry and Ourselves," by Jeffrey A. Cantor; (2) "Starting Again: The Brookhaven Success College," by Alice W. Villadsen; (3) "From Digital Divide to Digital Democracy," by Gerardo E. de los…

  3. Abstraction and art.

    PubMed Central

    Gortais, Bernard

    2003-01-01

    In a given social context, artistic creation comprises a set of processes, which relate to the activity of the artist and the activity of the spectator. Through these processes we see and understand that the world is vaster than it is said to be. Artistic processes are mediated experiences that open up the world. A successful work of art expresses a reality beyond actual reality: it suggests an unknown world using the means and the signs of the known world. Artistic practices incorporate the means of creation developed by science and technology and change forms as they change. Artists and the public follow different processes of abstraction at different levels, in the definition of the means of creation, of representation and of perception of a work of art. This paper examines how the processes of abstraction are used within the framework of the visual arts and abstract painting, which appeared during a period of growing importance for the processes of abstraction in science and technology, at the beginning of the twentieth century. The development of digital platforms and new man-machine interfaces allow multimedia creations. This is performed under the constraint of phases of multidisciplinary conceptualization using generic representation languages, which tend to abolish traditional frontiers between the arts: visual arts, drama, dance and music. PMID:12903659

  4. Annual Conference Abstracts

    ERIC Educational Resources Information Center

    Journal of Engineering Education, 1972

    1972-01-01

    Includes abstracts of papers presented at the 80th Annual Conference of the American Society for Engineering Education. The broad areas include aerospace, affiliate and associate member council, agricultural engineering, biomedical engineering, continuing engineering studies, chemical engineering, civil engineering, computers, cooperative…

  5. Abstracts of SIG Sessions.

    ERIC Educational Resources Information Center

    Proceedings of the ASIS Annual Meeting, 1994

    1994-01-01

    Includes abstracts of 18 special interest group (SIG) sessions. Highlights include natural language processing, information science and terminology science, classification, knowledge-intensive information systems, information value and ownership issues, economics and theories of information science, information retrieval interfaces, fuzzy thinking…

  6. RESEARCH ABSTRACTS, VOLUME VI.

    ERIC Educational Resources Information Center

    COLETTE, SISTER M.

    THIS SIXTH VOLUME OF RESEARCH ABSTRACTS PRESENTS REPORTS OF 35 RESEARCH STUDIES COMPLETED BY CANDIDATES FOR THE MASTER'S DEGREE AT THE CARDINAL STRITCH COLLEGE IN 1964. TWENTY-NINE STUDIES ARE CONCERNED WITH READING, AND SIX ARE CONCERNED WITH THE EDUCATION OF THE MENTALLY HANDICAPPED. OF THE READING STUDIES, FIVE PERTAIN TO THE JUNIOR HIGH LEVEL…

  7. Learning Abstracts, 1999.

    ERIC Educational Resources Information Center

    League for Innovation in the Community Coll.

    This document contains volume two of Learning Abstracts, a bimonthly newsletter from the League for Innovation in the Community College. Articles in these seven issues include: (1) "Get on the Fast Track to Learning: An Accelerated Associate Degree Option" (Gerardo E. de los Santos and Deborah J. Cruise); (2) "The Learning College:…

  8. Annual Conference Abstracts

    ERIC Educational Resources Information Center

    Engineering Education, 1976

    1976-01-01

    Presents the abstracts of 158 papers presented at the American Society for Engineering Education's annual conference at Knoxville, Tennessee, June 14-17, 1976. Included are engineering topics covering education, aerospace, agriculture, biomedicine, chemistry, computers, electricity, acoustics, environment, mechanics, and women. (SL)

  9. Making the Abstract Concrete

    ERIC Educational Resources Information Center

    Potter, Lee Ann

    2005-01-01

    President Ronald Reagan nominated a woman to serve on the United States Supreme Court. He did so through a single-page form letter, completed in part by hand and in part by typewriter, announcing Sandra Day O'Connor as his nominee. While the document serves as evidence of a historic event, it is also a tangible illustration of abstract concepts…

  10. Abstracts of SIG Sessions.

    ERIC Educational Resources Information Center

    Proceedings of the ASIS Annual Meeting, 1995

    1995-01-01

    Presents abstracts of 15 special interest group (SIG) sessions. Topics include navigation and information utilization in the Internet, natural language processing, automatic indexing, image indexing, classification, users' models of database searching, online public access catalogs, education for information professions, information services,…

  11. Seismic Consequence Abstraction

    SciTech Connect

    M. Gross

    2004-10-25

    The primary purpose of this model report is to develop abstractions for the response of engineered barrier system (EBS) components to seismic hazards at a geologic repository at Yucca Mountain, Nevada, and to define the methodology for using these abstractions in a seismic scenario class for the Total System Performance Assessment - License Application (TSPA-LA). A secondary purpose of this model report is to provide information for criticality studies related to seismic hazards. The seismic hazards addressed herein are vibratory ground motion, fault displacement, and rockfall due to ground motion. The EBS components are the drip shield, the waste package, and the fuel cladding. The requirements for development of the abstractions and the associated algorithms for the seismic scenario class are defined in ''Technical Work Plan For: Regulatory Integration Modeling of Drift Degradation, Waste Package and Drip Shield Vibratory Motion and Seismic Consequences'' (BSC 2004 [DIRS 171520]). The development of these abstractions will provide a more complete representation of flow into and transport from the EBS under disruptive events. The results from this development will also address portions of integrated subissue ENG2, Mechanical Disruption of Engineered Barriers, including the acceptance criteria for this subissue defined in Section 2.2.1.3.2.3 of the ''Yucca Mountain Review Plan, Final Report'' (NRC 2003 [DIRS 163274]).

  12. Abstraction through Game Play

    ERIC Educational Resources Information Center

    Avraamidou, Antri; Monaghan, John; Walker, Aisha

    2012-01-01

    This paper examines the computer game play of an 11-year-old boy. In the course of building a virtual house he developed and used, without assistance, an artefact and an accompanying strategy to ensure that his house was symmetric. We argue that the creation and use of this artefact-strategy is a mathematical abstraction. The discussion…

  13. More insight into the fate of biomedical meeting abstracts: a systematic review

    PubMed Central

    von Elm, Erik; Costanza, Michael C; Walder, Bernhard; Tramèr, Martin R

    2003-01-01

    Background It has been estimated that about 45% of abstracts that are accepted for presentation at biomedical meetings will subsequently be published in full. The acceptance of abstracts at meetings and their fate after initial rejection are less well understood. We set out to estimate the proportion of abstracts submitted to meetings that are eventually published as full reports, and to explore factors that are associated with meeting acceptance and successful publication. Methods Studies analysing acceptance of abstracts at biomedical meetings or their subsequent full publication were searched in MEDLINE, OLDMEDLINE, EMBASE, Cochrane Library, CINAHL, BIOSIS, Science Citation Index Expanded, and by hand searching of bibliographies and proceedings. We estimated rates of abstract acceptance and of subsequent full publication, and identified abstract and meeting characteristics associated with acceptance and publication, using logistic regression analysis, survival-type analysis, and meta-analysis. Results Analysed meetings were held between 1957 and 1999. Of 14945 abstracts that were submitted to 43 meetings, 46% were accepted. The rate of full publication was studied with 19123 abstracts that were presented at 234 meetings. Using survival-type analysis, we estimated that 27% were published after two, 41% after four, and 44% after six years. Of 2412 abstracts that were rejected at 24 meetings, 27% were published despite rejection. Factors associated with both abstract acceptance and subsequent publication were basic science and positive study outcome. Large meetings and those held outside the US were more likely to accept abstracts. Abstracts were more likely to be published subsequently if presented either orally, at small meetings, or at a US meeting. Abstract acceptance itself was strongly associated with full publication. Conclusions About one third of abstracts submitted to biomedical meetings were published as full reports. Acceptance at meetings and

  14. In vitro screen of a small molecule inhibitor drug library identifies multiple compounds that synergize with oncolytic myxoma virus against human brain tumor-initiating cells

    PubMed Central

    McKenzie, Brienne A.; Zemp, Franz J.; Pisklakova, Alexandra; Narendran, Aru; McFadden, Grant; Lun, Xueqing; Kenchappa, Rajappa S.; Kurz, Ebba U.; Forsyth, Peter A.

    2015-01-01

    Background Brain tumor-initiating cells (BTICs) are stem-like cells hypothesized to form a disease reservoir that mediates tumor recurrence in high-grade gliomas. Oncolytic virotherapy uses replication-competent viruses to target and kill malignant cells and has been evaluated in clinic for glioma therapy with limited results. Myxoma virus (MyxV) is a safe and highly effective oncolytic virus (OV) in conventional glioma models but, as seen with other OVs, is only modestly effective for patient-derived BTICs. The objective of this study was to determine whether MyxV treatment against human BTICs could be improved by combining chemotherapeutics and virotherapy. Methods A 73-compound library of drug candidates in clinical use or preclinical development was screened to identify compounds that sensitize human BTICs to MyxV treatment in vitro, and synergy was evaluated mathematically in lead compounds using Chou-Talalay analyses. The effects of combination therapy on viral gene expression and viral replication were also assessed. Results Eleven compounds that enhance MyxV efficacy were identified, and 6 were shown to synergize with the virus using Chou-Talalay analyses. Four of the synergistic compounds were shown to significantly increase viral gene expression, indicating a potential mechanism for synergy. Three highly synergistic compounds (axitinib, a VEGFR inhibitor; rofecoxib, a cyclooxygenase-2 inhibitor; and pemetrexed, a folate anti-metabolite) belong to classes of compounds that have not been previously shown to synergize with oncolytic viruses in vitro. Conclusions This study has identified multiple novel drug candidates that synergistically improve MyxV efficacy in a preclinical BTIC glioma model. PMID:25605818

  15. Groundwater abstraction pollution risk assessment.

    PubMed

    Lytton, L; Howe, S; Sage, R; Greenaway, P

    2003-01-01

    A generic groundwater pollution risk assessment methodology has been developed to enable the evaluation and ranking of the potential risk of pollution to groundwater abstractions. The ranking can then be used to prioritise risk management or mitigation procedures in a robust and quantifiable framework and thus inform business investment decisions. The risk assessment consider the three components of the pollution transport model: source-pathway-receptor. For groundwater abstractions these correspond to land use (with associated pollutants and shallow subsurface characteristics), aquifer and the abstraction borehole. An hierarchical approach was chosen to allow the risk assessment to be successfully carried out with different quality data for different parts of the model. The 400-day groundwater protection zone defines the catchment boundary that form the spatial limit of the land use audit for each receptor. A risk score is obtained for each land use (potential pollution source) within the catchment. These scores are derived by considering the characteristics (such as load, persistence and toxicity) of all pollutants pertaining to each land use, their on-site management and the potential for the unsaturated subsurface to attenuate their effects in the event of a release. Risk scores are also applied to the aquifer characteristics (as pollutant pathway) and to the abstraction borehole (as pollutant receptor). Each risk score is accompanied by an uncertainty score which provides a guide to the confidence in the data used to compile the risk assessment. The application of the methodology has highlighted a number of problems in this type of work and results of initial case studies are being used to trial alternative scoring methods and a more simplified approach to accelerate the process of pollution risk assessment.

  16. A Critical Assessment of Marine Aquarist Biodiversity Data and Commercial Aquaculture: Identifying Gaps in Culture Initiatives to Inform Local Fisheries Managers

    PubMed Central

    Murray, Joanna M.; Watson, Gordon J.

    2014-01-01

    It is widely accepted that if well managed, the marine aquarium trade could provide socio-economic stability to local communities while incentivising the maintenance of coral reefs. However, the trade has also been implicated as having potentially widespread environmental impacts that has in part driven developments in aquaculture to relieve wild collection pressures. This study investigates the biodiversity in hobbyist aquaria (using an online survey) and those species currently available from an aquaculture source (commercial data and hobbyist initiatives) in the context of a traffic light system to highlight gaps in aquaculture effort and identify groups that require fisheries assessments. Two hundred and sixty nine species including clown fish, damsels, dotty backs, angelfish, gobies, sea horses and blennies, have reported breeding successes by hobbyists, a pattern mirrored by the European and US commercial organisations. However, there is a mismatch (high demand and low/non-existent aquaculture) for a number of groups including tangs, starfish, anemones and hermit crabs, which we recommend are priority candidates for local stock assessments. Hobbyist perception towards the concept of a sustainable aquarium trade is also explored with results demonstrating that only 40% of respondents were in agreement with industry and scientists who believe the trade could be an exemplar of a sustainable use of coral reefs. We believe that a more transparent evidence base, including the publication of the species collected and cultured, will go some way to align the concept of a sustainable trade across industry stakeholders and better inform the hobbyist when purchasing their aquaria stock. We conclude by proposing that a certification scheme established with government support is the most effective way to move towards a self-regulating industry. It would prevent industry “greenwashing” from multiple certification schemes, alleviate conservation concerns, and, ultimately

  17. A critical assessment of marine aquarist biodiversity data and commercial aquaculture: identifying gaps in culture initiatives to inform local fisheries managers.

    PubMed

    Murray, Joanna M; Watson, Gordon J

    2014-01-01

    It is widely accepted that if well managed, the marine aquarium trade could provide socio-economic stability to local communities while incentivising the maintenance of coral reefs. However, the trade has also been implicated as having potentially widespread environmental impacts that has in part driven developments in aquaculture to relieve wild collection pressures. This study investigates the biodiversity in hobbyist aquaria (using an online survey) and those species currently available from an aquaculture source (commercial data and hobbyist initiatives) in the context of a traffic light system to highlight gaps in aquaculture effort and identify groups that require fisheries assessments. Two hundred and sixty nine species including clown fish, damsels, dotty backs, angelfish, gobies, sea horses and blennies, have reported breeding successes by hobbyists, a pattern mirrored by the European and US commercial organisations. However, there is a mismatch (high demand and low/non-existent aquaculture) for a number of groups including tangs, starfish, anemones and hermit crabs, which we recommend are priority candidates for local stock assessments. Hobbyist perception towards the concept of a sustainable aquarium trade is also explored with results demonstrating that only 40% of respondents were in agreement with industry and scientists who believe the trade could be an exemplar of a sustainable use of coral reefs. We believe that a more transparent evidence base, including the publication of the species collected and cultured, will go some way to align the concept of a sustainable trade across industry stakeholders and better inform the hobbyist when purchasing their aquaria stock. We conclude by proposing that a certification scheme established with government support is the most effective way to move towards a self-regulating industry. It would prevent industry "greenwashing" from multiple certification schemes, alleviate conservation concerns, and, ultimately

  18. Generalized Abstract Symbolic Summaries

    NASA Technical Reports Server (NTRS)

    Person, Suzette; Dwyer, Matthew B.

    2009-01-01

    Current techniques for validating and verifying program changes often consider the entire program, even for small changes, leading to enormous V&V costs over a program s lifetime. This is due, in large part, to the use of syntactic program techniques which are necessarily imprecise. Building on recent advances in symbolic execution of heap manipulating programs, in this paper, we develop techniques for performing abstract semantic differencing of program behaviors that offer the potential for improved precision.

  19. Abstraction Augmented Markov Models.

    PubMed

    Caragea, Cornelia; Silvescu, Adrian; Caragea, Doina; Honavar, Vasant

    2010-12-13

    High accuracy sequence classification often requires the use of higher order Markov models (MMs). However, the number of MM parameters increases exponentially with the range of direct dependencies between sequence elements, thereby increasing the risk of overfitting when the data set is limited in size. We present abstraction augmented Markov models (AAMMs) that effectively reduce the number of numeric parameters of k(th) order MMs by successively grouping strings of length k (i.e., k-grams) into abstraction hierarchies. We evaluate AAMMs on three protein subcellular localization prediction tasks. The results of our experiments show that abstraction makes it possible to construct predictive models that use significantly smaller number of features (by one to three orders of magnitude) as compared to MMs. AAMMs are competitive with and, in some cases, significantly outperform MMs. Moreover, the results show that AAMMs often perform significantly better than variable order Markov models, such as decomposed context tree weighting, prediction by partial match, and probabilistic suffix trees.

  20. Identifying evaluation considerations for the recovery and restoration from the 2010 Gulf of Mexico oil spill: An initial appraisal of stakeholder concerns and values.

    PubMed

    Carriger, John F; Jordan, Stephen J; Kurtz, Janis C; Benson, William H

    2015-07-01

    Understanding what can be achieved and what should be avoided by environmental management decisions requires an understanding of values, or what is cared about in a decision. Decision analysis provides tools and processes for constructing objectives that transparently reflect the values being considered in environmental management decisions. The present study demonstrates parts of the initial decision analysis steps for identifying a decision context and constructing objectives for the recovery and long-term restoration of the Gulf of Mexico following the 2010 Deepwater Horizon oil spill. From a review of multiple reports, including those developed by policy makers and nongovernmental organizations, a preliminary structuring of concerns and considerations into objectives was derived to highlight features of importance in the recovery from the spill and long-term restoration. The fundamental objectives constructed for the long-term restoration context reflect broader concerns regarding well-being and quality of life. When developed through stakeholder engagement processes, clarifying objectives can potentially 1) lend insight into the values that can be affected, 2) meaningfully include stakeholders in the decision-making process, 3) enhance transparency and communication, and 4) develop high-impact management strategies reflecting broad public interests. This article is a US government work and is in the public domain in the United States of America.

  1. Research Abstracts of 1980.

    DTIC Science & Technology

    1980-12-01

    ABSTRACTS OF 1980. 9 - DTIC ELECTEf ii S AN3O 1981j _NAVAL DISTRIBUTION SMT:MIT DENTAL RESEARCH Approved for PUbDiC T INSTITE iii~2 YA3 It81 Naval...Medical Research apd Development Command 30 £ Bethesda, Maryland ( *- i - NTIS - GRA&I DTIC TAB - Urrannouneed NAVAL DENTAL RESEARCH INSTITUTE...r1 w American Assoctat/ion for Dental Research, 58th Annual Session, Los Angeles, California, March 20-23, 1980. 1. AV6ERSON*, D. N., LANGELAND, K

  2. Research Abstracts of 1979.

    DTIC Science & Technology

    1979-12-01

    7 AD-AO82 309 NAVAL DENTAL RESEARCH INST GREAT LAKES IL F/6 6/9 RESCH ABTAT79 991 UNCLASSIFIED NORI-PR-79-11 NL ’NDRI-PR 79-11 December 1979...RESEARCH ABSTRACTS OF 1979 OTICSELZCreD MAR 2?718 S A NAVAL DENTAL RESEARCH INSTITUTE Naval Medical Research and Development Command Bethesda, Maryland...8G 3 23 O4ൌ p.,. ... ....-- - I -- - ’.... .I l l ---,, .. . = ., , ." .;’.- I 1 IV NAVAL DENTAL RESEARCH INSTITUTE NAVAL BASE, BLDG. I-H GREAT LAKES

  3. Analysis of complex networks using aggressive abstraction.

    SciTech Connect

    Colbaugh, Richard; Glass, Kristin.; Willard, Gerald

    2008-10-01

    This paper presents a new methodology for analyzing complex networks in which the network of interest is first abstracted to a much simpler (but equivalent) representation, the required analysis is performed using the abstraction, and analytic conclusions are then mapped back to the original network and interpreted there. We begin by identifying a broad and important class of complex networks which admit abstractions that are simultaneously dramatically simplifying and property preserving we call these aggressive abstractions -- and which can therefore be analyzed using the proposed approach. We then introduce and develop two forms of aggressive abstraction: 1.) finite state abstraction, in which dynamical networks with uncountable state spaces are modeled using finite state systems, and 2.) onedimensional abstraction, whereby high dimensional network dynamics are captured in a meaningful way using a single scalar variable. In each case, the property preserving nature of the abstraction process is rigorously established and efficient algorithms are presented for computing the abstraction. The considerable potential of the proposed approach to complex networks analysis is illustrated through case studies involving vulnerability analysis of technological networks and predictive analysis for social processes.

  4. Identifying families with complex needs after an initial child abuse investigation: A comparison of demographics and needs related to domestic violence, mental health, and substance use.

    PubMed

    Simon, James David; Brooks, Devon

    2017-03-16

    Families with complex needs related to domestic violence, mental health, and substance use have some of the worst child protective services (CPS) outcomes. Although many of these families are identified during a CPS investigation and subsequently referred to home-based postinvestigation services (HBPS), many are re-reported to CPS, so it is important to understand the postinvestigation experiences of this vulnerable group. Therefore, this study compared families with and without complex needs to understand their uniquedemographics, needs, and postinvestigation outcomes. The sample consisted of 2008 caregivers who received HBPS following an initial CPS investigation. The Family Assessment Form (FAF) was used to measure family functioning in eight domains using a 1-5 scale with higher ratings representing worse functioning. Complex needs were indicated by a mean FAF score of 3 or higher for either domestic violence, mental health, or substance use. Using Pearson chi-square analyses and two-sample t-tests, comparisons were made between families with (n=836) and without (n=1172) complex needs. Half of caregivers with complex needs had a history of abuse, 25% had three to five needs, and nearly half had six to eight needs; 90% of caregivers without complex needs had zero to two needs. Furthermore, caregivers with complex needs had higher mean scores for concrete, educational, and clinical needs. These findings highlight the importance of recognizing variation among families referred to HBPS and accurate screening to ensure that families with complex needs are offered and receive services matched to their unique characteristics and needs.

  5. Writing a successful research abstract.

    PubMed

    Bliss, Donna Z

    2012-01-01

    Writing and submitting a research abstract provides timely dissemination of the findings of a study and offers peer input for the subsequent development of a quality manuscript. Acceptance of abstracts is competitive. Understanding the expected content of an abstract, the abstract review process and tips for skillful writing will improve the chance of acceptance.

  6. Compilation of Theses Abstracts

    DTIC Science & Technology

    2004-12-01

    METEOROLOGY An Analysis of a Dust Storm Impacting Operation Iraqi Freedom, 25–27 March 2003 ................................ 75 TABLE OF CONTENTS xii...ANALYSIS OF A DUST STORM IMPACTING OPERATION IRAQI FREEDOM, 25–27 MARCH 2003 John W. Anderson–Captain, United States Air Force B.S., University of... dust storm initiated by the passage of a synoptically driven cold front. This storm impacted ground and air operations across the entire area of

  7. Research Abstracts of 1981.

    DTIC Science & Technology

    1981-12-01

    sulfate (SLS), Teepol 610, Tween 80 and Tween 60. Five fresh isolates each of Bacteroides melaninogenicus ss intermedius , B. ochraceus and Fusobacterium... Streptococcus mutans cells on hydroxyapatite surfaces. The enzyme was then tested in animals to evaluate its caries-preventive potential. Seventeen day-old... Streptococcus mutans in initial plaque samples grown in a selective colorimetric broth medium (Shklair, et al., IADR Abst. 241, 1976) and the remaining 4

  8. Keratin 13 Is Enriched in Prostate Tubule-Initiating Cells and May Identify Primary Prostate Tumors that Metastasize to the Bone

    PubMed Central

    Zhang, Baohui; Huo, Lihong; Lai, Kevin; Li, Xinmin; Galet, Colette; Grogan, Tristan R.; Elashoff, David; Freedland, Stephen J.; Rettig, Matthew; Aronson, William J.; Knudsen, Beatrice S.; Lewis, Michael S.; Garraway, Isla P.

    2016-01-01

    Background Benign human prostate tubule-initiating cells (TIC) and aggressive prostate cancer display common traits, including tolerance of low androgen levels, resistance to apoptosis, and microenvironment interactions that drive epithelial budding and outgrowth. TIC can be distinguished from epithelial and stromal cells that comprise prostate tissue via cell sorting based upon Epcam, CD44, and CD49f antigenic profiles. Fetal prostate epithelial cells (FC) possess a similar antigenic profile to adult TIC and are capable of inducing tubule formation. To identify the TIC niche in human prostate tissue, differential keratin (KRT) expression was evaluated. Results Gene expression data generated from Affymetrix Gene Chip human U133 Plus 2.0 array of sorted adult and fetal epithelial cells revealed KRT13 to be significantly enriched in FC and TIC compared to basal cells (BC) and luminal cells (LC) (p<0.001). Enriched KRT13 expression was confirmed by RT-PCR and cytospin immunostaining. Immunohistochemical analysis of KRT13 expression revealed rare KRT13+ epithelia throughout prostatic ducts/acini in adult tissue specimens and differentiated tubules in 24-week recombinant grafts, In contrast, abundant KRT13 expression was observed in developing ducts/acini in fetal prostate and cord-like structures composing 8-week recombinant grafts. Immunostaining of a prostate tissue microarray revealed KRT13+ tumor foci in approximately 9% of cases, and this subset displayed significantly shorter time to recurrence (p = 0.031), metastases (p = 0.032), and decreased overall survival (p = 0.004). Diagnostic prostate needle biopsies (PNBX) from untreated patients with concurrent bone metastases (clinical stage M1) displayed KRT13+ tumor foci, as did bone metastatic foci. Conclusions The expression profile of KRT13 in benign fetal and adult prostate tissue and in recombinant grafts, as well as the frequency of KRT13 expression in primary and metastatic prostate cancer indicates that it

  9. Identifying Growth of Structures in the Zagros Fold and Thrust Belt: Initial Time Series Results and Evaluation of Precipitable Water Vapor Effects

    NASA Astrophysics Data System (ADS)

    Barnhart, W. D.; Lohman, R. B.

    2010-12-01

    In this work, we combine InSAR observations with independent satellite-based measurements of precipitable water vapor in an attempt to identify aseismic deformation in a fold and thrust belt. We use the precipitable water vapor data to assess the magnitude of deformation that may be induced by atmospheric noise that is correlated in time given a particular data set. The Zagros Fold and Thrust Belt (ZFTB) of western and southwestern Iran accommodates active collision between the Arabian and Eurasian plates. Current convergence rates between Arabia and Eurasia are 25-36 mm/yr, with roughly half of the shortening accommodated in the ZFTB. While rates of seismicity in the ZFTB are high, large (>Mw 7.0) surface rupturing earthquakes are rare, and calculations of seismic moment rates suggest that only 10-30% of the total shortening is accommodated seismically. Thus, a significant amount of strain must be accommodated aseismically, presumably though the deformation of the large whale-back anticlines characteristic of the ZFTB. In this work, we present the initial results of an InSAR time series analysis in the Bandar-e-Abbas region of the southern ZFTB. We aim to identify interseismic strain accumulation and growth of the folds in order to better our understanding of the relative roles of seismic and aseismic deformation on the formation of long lived geologic structures. We implement the Small Baseline Subset (SBAS) time series approach to calculate line of sight (LOS) surface velocities from ENVISAT and ERS descending Tracks 435 and 163 between February 1993 and September 2010. A key assumption of SBAS is that correlated atmospheric noise is random in sign over time and should have zero effect on the time series if the number of scenes is large enough. To investigate if the seasonal distribution of available dates induces a biased atmospheric noise signal that may contribute to our computed LOS velocities, we use MODIS and MERIS precipitable water vapor data to analyze

  10. Exoplanets and Multiverses (Abstract)

    NASA Astrophysics Data System (ADS)

    Trimble, V.

    2016-12-01

    (Abstract only) To the ancients, the Earth was the Universe, of a size to be crossed by a god in a day, by boat or chariot, and by humans in a lifetime. Thus an exoplanet would have been a multiverse. The ideas gradually separated over centuries, with gradual acceptance of a sun-centered solar system, the stars as suns likely to have their own planets, other galaxies beyond the Milky Way, and so forth. And whenever the community divided between "just one' of anything versus "many," the "manies" have won. Discoveries beginning in 1991 and 1995 have gradually led to a battalion or two of planets orbiting other stars, very few like our own little family, and to moderately serious consideration of even larger numbers of other universes, again very few like our own. I'm betting, however, on habitable (though not necessarily inhabited) exoplanets to be found, and habitable (though again not necessarily inhabited) universes. Only the former will yield pretty pictures.

  11. Abstraction of Drift Seepage

    SciTech Connect

    J.T. Birkholzer

    2004-11-01

    This model report documents the abstraction of drift seepage, conducted to provide seepage-relevant parameters and their probability distributions for use in Total System Performance Assessment for License Application (TSPA-LA). Drift seepage refers to the flow of liquid water into waste emplacement drifts. Water that seeps into drifts may contact waste packages and potentially mobilize radionuclides, and may result in advective transport of radionuclides through breached waste packages [''Risk Information to Support Prioritization of Performance Assessment Models'' (BSC 2003 [DIRS 168796], Section 3.3.2)]. The unsaturated rock layers overlying and hosting the repository form a natural barrier that reduces the amount of water entering emplacement drifts by natural subsurface processes. For example, drift seepage is limited by the capillary barrier forming at the drift crown, which decreases or even eliminates water flow from the unsaturated fractured rock into the drift. During the first few hundred years after waste emplacement, when above-boiling rock temperatures will develop as a result of heat generated by the decay of the radioactive waste, vaporization of percolation water is an additional factor limiting seepage. Estimating the effectiveness of these natural barrier capabilities and predicting the amount of seepage into drifts is an important aspect of assessing the performance of the repository. The TSPA-LA therefore includes a seepage component that calculates the amount of seepage into drifts [''Total System Performance Assessment (TSPA) Model/Analysis for the License Application'' (BSC 2004 [DIRS 168504], Section 6.3.3.1)]. The TSPA-LA calculation is performed with a probabilistic approach that accounts for the spatial and temporal variability and inherent uncertainty of seepage-relevant properties and processes. Results are used for subsequent TSPA-LA components that may handle, for example, waste package corrosion or radionuclide transport.

  12. Volume II: Compendium Abstracts

    DTIC Science & Technology

    2008-08-01

    materials, not clearly identified. The Mössbauer spectra of the as-grown sample suggest the presence of different phases of magnetic Fe nanoparticles ...in contrast to a single paramagnetic phase present in the catalyst before thermal treatment. Further optimization of the CVD parameters for...The lateral flow assay uses latex nanoparticles tagged with C-reactive protein (CRP) antibodies as well as gold nanoparticles tagged with CRP

  13. A Comparative Analysis of Meeting the Whole Child Initiatives through Standardized and Competency-Based Education Systems in Terms of Achievement and Meeting the Whole Child Initiatives: Comparing Professional Perceptions and Identified Measurable Results

    ERIC Educational Resources Information Center

    Ward, Jacqueline M.

    2011-01-01

    Traditional education (TE) largely uses a standardized (SbE) approach while alternatives (nTE) tend to more of a competency (CbE), or student-centered approach. This comparative analysis examines essential aspects of such pedagogies in determining the effectiveness of schooling systems in meeting the Whole Child Initiative (Souza, 1999; Carter et…

  14. Using abstract language signals power.

    PubMed

    Wakslak, Cheryl J; Smith, Pamela K; Han, Albert

    2014-07-01

    Power can be gained through appearances: People who exhibit behavioral signals of power are often treated in a way that allows them to actually achieve such power (Ridgeway, Berger, & Smith, 1985; Smith & Galinsky, 2010). In the current article, we examine power signals within interpersonal communication, exploring whether use of concrete versus abstract language is seen as a signal of power. Because power activates abstraction (e.g., Smith & Trope, 2006), perceivers may expect higher power individuals to speak more abstractly and therefore will infer that speakers who use more abstract language have a higher degree of power. Across a variety of contexts and conversational subjects in 7 experiments, participants perceived respondents as more powerful when they used more abstract language (vs. more concrete language). Abstract language use appears to affect perceived power because it seems to reflect both a willingness to judge and a general style of abstract thinking.

  15. 1986 annual information meeting. Abstracts

    SciTech Connect

    Not Available

    1986-01-01

    Abstracts are presented for the following papers: Geohydrological Research at the Y-12 Plant (C.S. Haase); Ecological Impacts of Waste Disposal Operations in Bear Creek Valley Near the Y-12 Plant (J.M. Loar); Finite Element Simulation of Subsurface Contaminant Transport: Logistic Difficulties in Handling Large Field Problems (G.T. Yeh); Dynamic Compaction of a Radioactive Waste Burial Trench (B.P. Spalding); Comparative Evaluation of Potential Sites for a High-Level Radioactive Waste Repository (E.D. Smith); Changing Priorities in Environmental Assessment and Environmental Compliance (R.M. Reed); Ecology, Ecotoxicology, and Ecological Risk Assessment (L.W. Barnthouse); Theory and Practice in Uncertainty Analysis from Ten Years of Practice (R.H. Gardner); Modeling Landscape Effects of Forest Decline (V.H. Dale); Soil Nitrogen and the Global Carbon Cycle (W.M. Post); Maximizing Wood Energy Production in Short-Rotation Plantations: Effect of Initial Spacing and Rotation Length (L.L. Wright); and Ecological Communities and Processes in Woodland Streams Exhibit Both Direct and Indirect Effects of Acidification (J.W. Elwood).

  16. Identifying the initiating events of anti-Listeria responses using mice with conditional loss of IFNγ receptor subunit 1 (IFNGR1)

    PubMed Central

    Lee, Sang Hun; Carrero, Javier A.; Uppaluri, Ravindra; White, J. Michael; Archambault, Jessica M.; Lai, Koon Siew; Chan, Szeman Ruby; Sheehan, Kathleen C. F.; Unanue, Emil R.; Schreiber, Robert D.

    2013-01-01

    Whereas IFNγ is required for resolution of Listeria monocytogenes infection, the identities of the IFNγ responsive cells that initiate the process remain unclear. We addressed this question using novel mice with conditional loss of the IFNγ receptor (IFNGR1). Itgax-cre+Ifngr1f/f mice with selective IFNγ unresponsiveness in CD8α+ dendritic cells displayed increased susceptibility to infection. This phenotype was due to the inability of IFNγ unresponsive CD8α+ DCs to produce the initial burst of IL-12 induced by IFNγ from TNFα-activated NK/NKT cells. The defect in early IL-12 production resulted in increased IL-4 production that established a myeloid cell environment favoring Listeria growth. Neutralization of IL-4 restored Listeria resistance in Itgax-cre+Ifngr1f/f mice. We also found that Itgax-cre+Ifngr1f/f mice survived infection with low dose Listeria due to a second wave of IL-12 produced by Ly6Chi monocytes. Thus, an IFNγ-driven cascade involving CD8α+ DCs and NK/NKT cells induces the rapid production of IL-12 that initiates the anti-Listeria response. PMID:24048899

  17. Initial basal cell carcinomas diagnosed in the National Campaign for Skin Cancer Prevention are smaller than those identified by the conventional medical referral system*

    PubMed Central

    Wakiyama, Thweicyka Pinheiro; França, Maria Laura Marconi; Carvalho, Larissa Pierri; Marques, Mariangela Esther Alencar; Miot, Hélio Amante; Schmitt, Juliano Vilaverde

    2017-01-01

    BACKGROUND Basal cell carcinoma is the malignant tumor most often diagnosed in the National Campaign for Skin Cancer Prevention (NCSCP). Little is known about the profile of these lesions compared to the profile of lesions diagnosed by conventional routes of public dermatological care. OBJECTIVE To identify if basal cell carcinomas identified in prevention campaigns and referred to surgery are smaller than those routinely removed in a same medical institution. METHODS Cross-sectional study including tumors routed from 2011-2014 campaigns and 84 anatomopathological reports of outpatients. RESULTS The campaigns identified 223 individuals with suspicious lesions among 2,531 examinations (9%), with 116 basal cell carcinomas removed. Anatomopathological examinations revealed that the primary lesions identified in the national campaigns were smaller than those referred to surgery by the conventional routes of public health care (28 [13-50] x 38 [20-113] mm2, p <0.01). On the other hand, after a mean follow-up of 15.6 ± 10.3 months, 31% of cases identified in campaigns showed new basal cell carcinoma lesions. STUDY LIMITATIONS Retrospective study and inaccuracies in the measurements of the lesions. CONCLUSIONS The NCSCP promotes an earlier treatment of basal cell carcinomas compared to patients referred to surgery by the conventional routes of public health care, which can result in lower morbidity rates and better prognosis. PMID:28225952

  18. Adult Education Dissertation Abstracts: 1968-1969.

    ERIC Educational Resources Information Center

    Grabowski, Stanley M., Ed.; Loague, Nehume, Ed.

    This bibliography contains citations, abstracts, and ordering information for 303 dissertations pertinent to the education or training of adults. Studies are classified by broad subject headings used in the ERIC Clearinghouse on Adult Education. Each section of the classification is identified by a four-digit number, with a one-, two-, or…

  19. Summer 2015 Internship Abstract

    NASA Technical Reports Server (NTRS)

    Smith, Courtney

    2015-01-01

    Green fluorescent protein (GFP) visually shows the expression of proteins by fluorescing when exposed to certain wavelengths of light. The GFP in this experiment was used to identify cells actively releasing viruses. The experiment focused on the effect of microgravity on the GFP expression of Akata B-cells infected with Epstein Barr Virus (EBV). Two flasks were prepared with 30 million cells each and two bioreactors were prepared with 50 million cells each. All four cultures were incubated for 16 days and fed every four days. Cellometer readings were taken on the feeding days to find cell size, viability, and GFP expression. In addition, the cells were treated with Propodium monoazide (PMA) and run through real time PCR to determine viral load on the feeding days. On the International Space Station air samples are taken to analyze the bacterial and fungal organisms in the air. The Sartorius Portable Airport is being investigated for potential use on the ISS to analyze for viral content in the air. Multiple samples were taken around Johnson Space Center building 37 and in Clear Lake Pediatric Clinic. The filter used was the gelatin membrane filter and the DNA was extracted directly from the filter. The DNA was then run through real time PCR for Varicella Zoster Virus (VZV) and EBV as well as GAPDH to test for the presence of DNA. The results so far have shown low DNA yield and no positive results for VZV or EBV. Further inquiry involves accurately replicating an atmosphere with high viral load from saliva as would be found on the ISS to run the air sampler in. Another line of research is stress hormones that may be correlated to the reactivation of latent viruses. The stress hormones from saliva samples are analyzed rather than blood samples. The quantity found in saliva shows the quantity of the hormones actually attached to cells and causing a reaction, whereas in the blood the quantity of hormones is the total amount released to cause a reaction. The particular

  20. The ADS Abstract Service: One Year Old

    NASA Astrophysics Data System (ADS)

    Grant, C. Stern; Kurtz, M. J.; Eichhorn, G.

    1994-05-01

    One year after its initial release the ADS Abstract Service has become quite widely used. More than 1000 different people use it per month, making about 20,000 queries and obtaining a couple of hundred thousand pieces of bibliographic information. In February a WWW connection was released, it has been heavily used. The collaboration with SIMBAD, released in January, allows one to make complex queries about work on particular objects. For example one may search for all papers which SIMBAD says are about M87, and which contain the words ``globular cluster'' in the abstract, thus getting the 65 papers on the M87 globular cluster system. One can also look for papers which have the words ``M87 globular clusters'' in the abstract, but are not listed in SIMBAD; this obtains another 19 papers, mostly conference procedings, about the M87 globular cluster system. The figure shows the list of non-SIMBAD papers.

  1. Grounding Abstractness: Abstract Concepts and the Activation of the Mouth.

    PubMed

    Borghi, Anna M; Zarcone, Edoardo

    2016-01-01

    One key issue for theories of cognition is how abstract concepts, such as freedom, are represented. According to the WAT (Words As social Tools) proposal, abstract concepts activate both sensorimotor and linguistic/social information, and their acquisition modality involves the linguistic experience more than the acquisition of concrete concepts. We report an experiment in which participants were presented with abstract and concrete definitions followed by concrete and abstract target-words. When the definition and the word matched, participants were required to press a key, either with the hand or with the mouth. Response times and accuracy were recorded. As predicted, we found that abstract definitions and abstract words yielded slower responses and more errors compared to concrete definitions and concrete words. More crucially, there was an interaction between the target-words and the effector used to respond (hand, mouth). While responses with the mouth were overall slower, the advantage of the hand over the mouth responses was more marked with concrete than with abstract concepts. The results are in keeping with grounded and embodied theories of cognition and support the WAT proposal, according to which abstract concepts evoke linguistic-social information, hence activate the mouth. The mechanisms underlying the mouth activation with abstract concepts (re-enactment of acquisition experience, or re-explanation of the word meaning, possibly through inner talk) are discussed. To our knowledge this is the first behavioral study demonstrating with real words that the advantage of the hand over the mouth is more marked with concrete than with abstract concepts, likely because of the activation of linguistic information with abstract concepts.

  2. Grounding Abstractness: Abstract Concepts and the Activation of the Mouth

    PubMed Central

    Borghi, Anna M.; Zarcone, Edoardo

    2016-01-01

    One key issue for theories of cognition is how abstract concepts, such as freedom, are represented. According to the WAT (Words As social Tools) proposal, abstract concepts activate both sensorimotor and linguistic/social information, and their acquisition modality involves the linguistic experience more than the acquisition of concrete concepts. We report an experiment in which participants were presented with abstract and concrete definitions followed by concrete and abstract target-words. When the definition and the word matched, participants were required to press a key, either with the hand or with the mouth. Response times and accuracy were recorded. As predicted, we found that abstract definitions and abstract words yielded slower responses and more errors compared to concrete definitions and concrete words. More crucially, there was an interaction between the target-words and the effector used to respond (hand, mouth). While responses with the mouth were overall slower, the advantage of the hand over the mouth responses was more marked with concrete than with abstract concepts. The results are in keeping with grounded and embodied theories of cognition and support the WAT proposal, according to which abstract concepts evoke linguistic-social information, hence activate the mouth. The mechanisms underlying the mouth activation with abstract concepts (re-enactment of acquisition experience, or re-explanation of the word meaning, possibly through inner talk) are discussed. To our knowledge this is the first behavioral study demonstrating with real words that the advantage of the hand over the mouth is more marked with concrete than with abstract concepts, likely because of the activation of linguistic information with abstract concepts. PMID:27777563

  3. Mechanical Engineering Department technical abstracts

    SciTech Connect

    Denney, R.M.

    1982-07-01

    The Mechanical Engineering Department publishes listings of technical abstracts twice a year to inform readers of the broad range of technical activities in the Department, and to promote an exchange of ideas. Details of the work covered by an abstract may be obtained by contacting the author(s). Overall information about current activities of each of the Department's seven divisions precedes the technical abstracts.

  4. Ocular Granulocytic Sarcoma as an Initial Clinical Presentation of Acute Myeloid Leukemia Identified on Flurodeoxyglucose Positron Emission Tomography/Computed Tomography

    PubMed Central

    Chandra, Piyush; Purandare, Nilendu; Shah, Sneha; Agrawal, Archi; Rangarajan, Venkatesh

    2017-01-01

    Granulocytic sarcoma (GS) or chloroma, rare extramedullary manifestation of acute myeloid leukemia and not infrequently, can be presenting clinical feature. Multiple studies have demonstrated the clinical utility of fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) in early detection and follow-up assessment of GS after chemotherapy. Commonly involved areas include bones, lymph nodes, breasts, and skin and not uncommonly, the disease can be multifocal. We present a rare case of ocular GS, where FDG-PET/CT in addition to the identifying the ocular mass, revealed multiple clinically occult extramedullary lesions. PMID:28242990

  5. Leadership Abstracts; Volume 4, 1991.

    ERIC Educational Resources Information Center

    Doucette, Don, Ed.

    1991-01-01

    "Leadership Abstracts" is published bimonthly and distributed to the chief executive officer of every two-year college in the United States and Canada. This document consists of the 15 one-page abstracts published in 1991. Addressing a variety of topics of interest to the community college administrators, this volume includes: (1) "Delivering the…

  6. Innovation Abstracts, Volume XV, 1993.

    ERIC Educational Resources Information Center

    Roueche, Suanne D., Ed.

    1993-01-01

    This volume of 30 one- to two-page abstracts from 1993 highlights a variety of innovative approaches to teaching and learning in the community college. Topics covered in the abstracts include: (1) role-playing to encourage critical thinking; (2) team learning techniques to cultivate business skills; (3) librarian-instructor partnerships to create…

  7. Vague Language in Conference Abstracts

    ERIC Educational Resources Information Center

    Cutting, Joan

    2012-01-01

    This study examined abstracts for a British Association for Applied Linguistics conference and a Sociolinguistics Symposium, to define the genre of conference abstracts in terms of vague language, specifically universal general nouns (e.g. people) and research general nouns (e.g. results), and to discover if the language used reflected the level…

  8. Technical abstracts: Mechanical engineering, 1990

    SciTech Connect

    Broesius, J.Y.

    1991-03-01

    This document is a compilation of the published, unclassified abstracts produced by mechanical engineers at Lawrence Livermore National Laboratory (LLNL) during the calendar year 1990. Many abstracts summarize work completed and published in report form. These are UCRL-JC series documents, which include the full text of articles to be published in journals and of papers to be presented at meetings, and UCID reports, which are informal documents. Not all UCIDs contain abstracts: short summaries were generated when abstracts were not included. Technical Abstracts also provides descriptions of those documents assigned to the UCRL-MI (miscellaneous) category. These are generally viewgraphs or photographs presented at meetings. An author index is provided at the back of this volume for cross referencing.

  9. Abstracts

    NASA Astrophysics Data System (ADS)

    2012-09-01

    Measuring cosmological parameters with GRBs: status and perspectives New interpretation of the Amati relation The SED Machine - a dedicated transient spectrograph PTF10iue - evidence for an internal engine in a unique Type Ic SN Direct evidence for the collapsar model of long gamma-ray bursts On pair instability supernovae and gamma-ray bursts Pan-STARRS1 observations of ultraluminous SNe The influence of rotation on the critical neutrino luminosity in core-collapse supernovae General relativistic magnetospheres of slowly rotating and oscillating neutron stars Host galaxies of short GRBs GRB 100418A: a bridge between GRB-associated hypernovae and SNe Two super-luminous SNe at z ~ 1.5 from the SNLS Prospects for very-high-energy gamma-ray bursts with the Cherenkov Telescope Array The dynamics and radiation of relativistic flows from massive stars The search for light echoes from the supernova explosion of 1181 AD The proto-magnetar model for gamma-ray bursts Stellar black holes at the dawn of the universe MAXI J0158-744: the discovery of a supersoft X-ray transient Wide-band spectra of magnetar burst emission Dust formation and evolution in envelope-stripped core-collapse supernovae The host galaxies of dark gamma-ray bursts Keck observations of 150 GRB host galaxies Search for properties of GRBs at large redshift The early emission from SNe Spectral properties of SN shock breakout MAXI observation of GRBs and short X-ray transients A three-dimensional view of SN 1987A using light echo spectroscopy X-ray study of the southern extension of the SNR Puppis A All-sky survey of short X-ray transients by MAXI GSC Development of the CALET gamma-ray burst monitor (CGBM)

  10. Abstracts

    ERIC Educational Resources Information Center

    Parsegian, V. L., Ed.

    1972-01-01

    Includes summaries of six articles dealing with engineering education, population management, blood sampling, international pollution control, environmental quality index, and scientific phases in political science. (CC)

  11. Identifying critically ill patients who benefit the most from nutrition therapy: the development and initial validation of a novel risk assessment tool

    PubMed Central

    2011-01-01

    Introduction To develop a scoring method for quantifying nutrition risk in the intensive care unit (ICU). Methods A prospective, observational study of patients expected to stay > 24 hours. We collected data for key variables considered for inclusion in the score which included: age, baseline APACHE II, baseline SOFA score, number of comorbidities, days from hospital admission to ICU admission, Body Mass Index (BMI) < 20, estimated % oral intake in the week prior, weight loss in the last 3 months and serum interleukin-6 (IL-6), procalcitonin (PCT), and C-reactive protein (CRP) levels. Approximate quintiles of each variable were assigned points based on the strength of their association with 28 day mortality. Results A total of 597 patients were enrolled in this study. Based on the statistical significance in the multivariable model, the final score used all candidate variables except BMI, CRP, PCT, estimated percentage oral intake and weight loss. As the score increased, so did mortality rate and duration of mechanical ventilation. Logistic regression demonstrated that nutritional adequacy modifies the association between the score and 28 day mortality (p = 0.01). Conclusions This scoring algorithm may be helpful in identifying critically ill patients most likely to benefit from aggressive nutrition therapy. PMID:22085763

  12. Newborn infants perceive abstract numbers.

    PubMed

    Izard, Véronique; Sann, Coralie; Spelke, Elizabeth S; Streri, Arlette

    2009-06-23

    Although infants and animals respond to the approximate number of elements in visual, auditory, and tactile arrays, only human children and adults have been shown to possess abstract numerical representations that apply to entities of all kinds (e.g., 7 samurai, seas, or sins). Do abstract numerical concepts depend on language or culture, or do they form a part of humans' innate, core knowledge? Here we show that newborn infants spontaneously associate stationary, visual-spatial arrays of 4-18 objects with auditory sequences of events on the basis of number. Their performance provides evidence for abstract numerical representations at the start of postnatal experience.

  13. Deficiencies in structured medical abstracts.

    PubMed

    Froom, P; Froom, J

    1993-07-01

    This study was carried out to determine if the content of structured abstracts conforms with recommendations of the Ad Hoc Working Group for the critical appraisal of the medical literature as adopted by the Annals of Internal Medicine. The study design was a survey. All articles published in Annals of Internal Medicine in 1991, excluding editorials, case-reports, literature reviews, decision analysis, studies in medical education, descriptive studies of clinical and basic phenomena, and papers lacking a structured abstract, were studied. Of a total of 150 articles, 20 were excluded. The abstract and text of each article were assessed for the presence of the following items; patient selection criteria, statements concerning extrapolation of findings, need for further study, and whether or not the information should be used now. Number of refusers, drop outs and reason(s) for drop outs were assessed for intervention and prospective cohort studies only. Deficiencies of assessed items were noted in both abstracts and texts. For abstracts, patient selection criteria, numbers of refusers, number of drop outs and reason(s) for drop outs were reported in 44.6% (58/130), 3.1% (4/130), 16.9% (14/83) and 2.4% (2/83) respectively. These items were reported more frequently in the texts 87.7% (114/130), 9.2% (12/130), 60.2% (50/83) and 37.3% (31/83) respectively (p < 0.05). Statements concerning extrapolation of findings, need for further study and use of information now were also more frequent in texts than abstracts (p < 0.0001). A large number of structured abstracts published in the Annals of Internal Medicine in 1991, lack information recommended by the Ad Hoc Working Group. Our findings should not be extrapolated to other journals requiring structured abstracts.

  14. Hydrogen energy. A bibliography with abstracts

    NASA Technical Reports Server (NTRS)

    1978-01-01

    Hydrogen Energy is a continuing bibliographic summary with abstracts of research and projections on the subject of hydrogen as a secondary fuel and as an energy carrier. This update to Hydrogen Energy cites additional references identified during the fourth quarter of 1978. It is the fourth in a 1978 quarterly series intended to provide current awareness to those interested in hydrogen energy. A series of cross indexes are included which track directly with those of the cumulative volume.

  15. Mechanical Engineering Department technical abstracts

    SciTech Connect

    Not Available

    1984-07-01

    The Mechanical Engineering Department publishes abstracts twice a year to inform readers of the broad range of technical activities in the Department, and to promote an exchange of ideas. Details of the work covered by an abstract may be obtained by contacting the author(s). General information about the current role and activities of each of the Department's seven divisions precedes the technical abstracts. Further information about a division's work may be obtained from the division leader, whose name is given at the end of each divisional summary. The Department's seven divisions are as follows: Nuclear Test Engineering Division, Nuclear Explosives Engineering Division, Weapons Engineering Division, Energy Systems Engineering Division, Engineering Sciences Division, Magnetic Fusion Engineering Division and Materials Fabrication Division.

  16. Meeting Abstracts - Annual Meeting 2016.

    PubMed

    2016-04-01

    The AMCP Abstracts program provides a forum through which authors can share their insights and outcomes of advanced managed care practice through publication in AMCP's Journal of Managed Care & Specialty Pharmacy (JMCP). Most of the reviewed and unreviewed abstracts are presented as posters so that interested AMCP meeting attendees can review findings and query authors. The Student/Resident/ Fellow poster presentation (unreviewed) is Wednesday, April 20, 2016, and the Professional poster presentation (reviewed) is Thursday, April 21. The Professional posters will also be displayed on Friday, April 22. The reviewed abstracts are published in the JMCP Meeting Abstracts supplement. The AMCP Managed Care & Specialty Pharmacy Annual Meeting 2016 in San Francisco, California, is expected to attract more than 3,500 managed care pharmacists and other health care professionals who manage and evaluate drug therapies, develop and manage networks, and work with medical managers and information specialists to improve the care of all individuals enrolled in managed care programs. Abstracts were submitted in the following categories: Research Report: describe completed original research on managed care pharmacy services or health care interventions. Examples include (but are not limited to) observational studies using administrative claims, reports of the impact of unique benefit design strategies, and analyses of the effects of innovative administrative or clinical programs. Economic Model: describe models that predict the effect of various benefit design or clinical decisions on a population. For example, an economic model could be used to predict the budget impact of a new pharmaceutical product on a health care system. Solving Problems in Managed Care: describe the specific steps taken to introduce a needed change, develop and implement a new system or program, plan and organize an administrative function, or solve other types of problems in managed care settings. These

  17. Abstraction and natural language semantics.

    PubMed Central

    Kayser, Daniel

    2003-01-01

    According to the traditional view, a word prototypically denotes a class of objects sharing similar features, i.e. it results from an abstraction based on the detection of common properties in perceived entities. I explore here another idea: words result from abstraction of common premises in the rules governing our actions. I first argue that taking 'inference', instead of 'reference', as the basic issue in semantics does matter. I then discuss two phenomena that are, in my opinion, particularly difficult to analyse within the scope of traditional semantic theories: systematic polysemy and plurals. I conclude by a discussion of my approach, and by a summary of its main features. PMID:12903662

  18. The Mystery of V523 Lyrae (Abstract)

    NASA Astrophysics Data System (ADS)

    Simonsen, M.

    2016-12-01

    (Abstract only) In the course of vetting submissions to VSX, it was suggested by a user that V523 Lyrae might be a Z Cam star. Investigations led to quite a bit of confusion initially because V523 Lyr was addressed in two separate papers on Kepler observations of cataclysmic variables, with two different light curves and conclusions as to its nature and classification. Adding to the confusion was the fact that the principle author of one paper was also a co-author on the other paper.

  19. Metaphoric Images from Abstract Concepts.

    ERIC Educational Resources Information Center

    Vizmuller-Zocco, Jana

    1992-01-01

    Discusses children's use of metaphors to create meaning, using as an example the pragmatic and "scientific" ways in which preschool children explain thunder and lightning to themselves. Argues that children are being shortchanged by modern scientific notions of abstractness and that they should be encouraged to create their own explanations of…

  20. Carry Groups: Abstract Algebra Projects

    ERIC Educational Resources Information Center

    Miller, Cheryl Chute; Madore, Blair F.

    2004-01-01

    Carry Groups are a wonderful collection of groups to introduce in an undergraduate Abstract Algebra course. These groups are straightforward to define but have interesting structures for students to discover. We describe these groups and give examples of in-class group projects that were developed and used by Miller.

  1. ERGONOMICS ABSTRACTS 48347-48982.

    ERIC Educational Resources Information Center

    Ministry of Technology, London (England). Warren Spring Lab.

    IN THIS COLLECTION OF ERGONOMICS ABSTRACTS AND ANNOTATIONS THE FOLLOWING AREAS OF CONCERN ARE REPRESENTED--GENERAL REFERENCES, METHODS, FACILITIES, AND EQUIPMENT RELATING TO ERGONOMICS, SYSTEMS OF MAN AND MACHINES, VISUAL, AUDITORY, AND OTHER SENSORY INPUTS AND PROCESSES (INCLUDING SPEECH AND INTELLIGIBILITY), INPUT CHANNELS, BODY MEASUREMENTS,…

  2. Does "Social Work Abstracts" Work?

    ERIC Educational Resources Information Center

    Holden, Gary; Barker, Kathleen; Covert-Vail, Lucinda; Rosenberg, Gary; Cohen, Stephanie A.

    2008-01-01

    Objective: The current study seeks to provide estimates of the adequacy of journal coverage in the Social Work Abstracts (SWA) database. Method: A total of 23 journals listed in the Journal Citation Reports social work category during the 1997 to 2005 period were selected for study. Issue-level coverage estimates were obtained for SWA and…

  3. Typographic Settings for Structured Abstracts.

    ERIC Educational Resources Information Center

    Hartley, James

    2000-01-01

    Lists some of the major typographic variables involved in structured abstracts (containing sub-headings). Illustrates how typography can affect clarity by presenting seven examples that illustrate the effects of these typographic variables in practice. Concludes with a final example of an effective approach. (SR)

  4. Handedness Shapes Children's Abstract Concepts

    ERIC Educational Resources Information Center

    Casasanto, Daniel; Henetz, Tania

    2012-01-01

    Can children's handedness influence how they represent abstract concepts like "kindness" and "intelligence"? Here we show that from an early age, right-handers associate rightward space more strongly with positive ideas and leftward space with negative ideas, but the opposite is true for left-handers. In one experiment, children indicated where on…

  5. Innovation Abstracts, Volume XVII, 1995.

    ERIC Educational Resources Information Center

    Roueche, Suanne D., Ed.

    1995-01-01

    The abstracts in this volume describe innovative approaches to teaching and learning in the community college. Topics covered include: (1) the use of message mapping for speaking and writing instruction; (2) group projects and portfolios as evaluation tools; (3) helping students become strategic learners; (4) using writing assignments to ensure…

  6. Chemical Abstracts' Document Delivery Service.

    ERIC Educational Resources Information Center

    Rollins, Stephen

    1984-01-01

    The Document Delivery Service offered by Chemical Abstracts is described in terms of the DIALORDER option on the Dialog information retrieval system, mail requests, and requests transmitted through OCLC's Interlibrary Loan system. Transmission costs, success rates, delivery rates, and other considerations in utilizing the service are included.…

  7. Automatic identification of abstract online groups

    DOEpatents

    Engel, David W; Gregory, Michelle L; Bell, Eric B; Cowell, Andrew J; Piatt, Andrew W

    2014-04-15

    Online abstract groups, in which members aren't explicitly connected, can be automatically identified by computer-implemented methods. The methods involve harvesting records from social media and extracting content-based and structure-based features from each record. Each record includes a social-media posting and is associated with one or more entities. Each feature is stored on a data storage device and includes a computer-readable representation of an attribute of one or more records. The methods further involve grouping records into record groups according to the features of each record. Further still the methods involve calculating an n-dimensional surface representing each record group and defining an outlier as a record having feature-based distances measured from every n-dimensional surface that exceed a threshold value. Each of the n-dimensional surfaces is described by a footprint that characterizes the respective record group as an online abstract group.

  8. Abstraction of Drift-Scale Coupled Processes

    SciTech Connect

    N.D. Francis; D. Sassani

    2000-03-31

    This Analysis/Model Report (AMR) describes an abstraction, for the performance assessment total system model, of the near-field host rock water chemistry and gas-phase composition. It also provides an abstracted process model analysis of potentially important differences in the thermal hydrologic (TH) variables used to describe the performance of a geologic repository obtained from models that include fully coupled reactive transport with thermal hydrology and those that include thermal hydrology alone. Specifically, the motivation of the process-level model comparison between fully coupled thermal-hydrologic-chemical (THC) and thermal-hydrologic-only (TH-only) is to provide the necessary justification as to why the in-drift thermodynamic environment and the near-field host rock percolation flux, the essential TH variables used to describe the performance of a geologic repository, can be obtained using a TH-only model and applied directly into a TSPA abstraction without recourse to a fully coupled reactive transport model. Abstraction as used in the context of this AMR refers to an extraction of essential data or information from the process-level model. The abstraction analysis reproduces and bounds the results of the underlying detailed process-level model. The primary purpose of this AMR is to abstract the results of the fully-coupled, THC model (CRWMS M&O 2000a) for effects on water and gas-phase composition adjacent to the drift wall (in the near-field host rock). It is assumed that drift wall fracture water and gas compositions may enter the emplacement drift before, during, and after the heating period. The heating period includes both the preclosure, in which the repository drifts are ventilated, and the postclosure periods, with backfill and drip shield emplacement at the time of repository closure. Although the preclosure period (50 years) is included in the process models, the postclosure performance assessment starts at the end of this initial period

  9. An Abstract Plan Preparation Language

    NASA Technical Reports Server (NTRS)

    Butler, Ricky W.; Munoz, Cesar A.

    2006-01-01

    This paper presents a new planning language that is more abstract than most existing planning languages such as the Planning Domain Definition Language (PDDL) or the New Domain Description Language (NDDL). The goal of this language is to simplify the formal analysis and specification of planning problems that are intended for safety-critical applications such as power management or automated rendezvous in future manned spacecraft. The new language has been named the Abstract Plan Preparation Language (APPL). A translator from APPL to NDDL has been developed in support of the Spacecraft Autonomy for Vehicles and Habitats Project (SAVH) sponsored by the Explorations Technology Development Program, which is seeking to mature autonomy technology for application to the new Crew Exploration Vehicle (CEV) that will replace the Space Shuttle.

  10. Object Classification via Planar Abstraction

    NASA Astrophysics Data System (ADS)

    Oesau, Sven; Lafarge, Florent; Alliez, Pierre

    2016-06-01

    We present a supervised machine learning approach for classification of objects from sampled point data. The main idea consists in first abstracting the input object into planar parts at several scales, then discriminate between the different classes of objects solely through features derived from these planar shapes. Abstracting into planar shapes provides a means to both reduce the computational complexity and improve robustness to defects inherent to the acquisition process. Measuring statistical properties and relationships between planar shapes offers invariance to scale and orientation. A random forest is then used for solving the multiclass classification problem. We demonstrate the potential of our approach on a set of indoor objects from the Princeton shape benchmark and on objects acquired from indoor scenes and compare the performance of our method with other point-based shape descriptors.

  11. Abstraction Techniques for Parameterized Verification

    DTIC Science & Technology

    2006-11-01

    difference, consider an example frequently discussed in the history of science, namely the Ptolemaic system in which the planet earth is surrounded by...tend to imagine systems with the human observer in the center. While a Ptolemaic viewpoint is known to be wrong (or, more precisely, infeasible) in...physics, it naturally appears in the systems we construct. Consequently, the Ptolemaic viewpoint yields a natural abstraction principle for computer

  12. Cryogenic foam insulation: Abstracted publications

    NASA Technical Reports Server (NTRS)

    Williamson, F. R.

    1977-01-01

    A group of documents were chosen and abstracted which contain information on the properties of foam materials and on the use of foams as thermal insulation at cryogenic temperatures. The properties include thermal properties, mechanical properties, and compatibility properties with oxygen and other cryogenic fluids. Uses of foams include applications as thermal insulation for spacecraft propellant tanks, and for liquefied natural gas storage tanks and pipelines.

  13. Directory of Energy Information Administration Model Abstracts

    SciTech Connect

    Not Available

    1986-07-16

    This directory partially fulfills the requirements of Section 8c, of the documentation order, which states in part that: The Office of Statistical Standards will annually publish an EIA document based on the collected abstracts and the appendices. This report contains brief statements about each model's title, acronym, purpose, and status, followed by more detailed information on characteristics, uses, and requirements. Sources for additional information are identified. All models active through March 1985 are included. The main body of this directory is an alphabetical list of all active EIA models. Appendix A identifies major EIA modeling systems and the models within these systems, and Appendix B identifies active EIA models by type (basic, auxiliary, and developing). EIA also leases models developed by proprietary software vendors. Documentation for these proprietary models is the responsibility of the companies from which they are leased. EIA has recently leased models from Chase Econometrics, Inc., Data Resources, Inc. (DRI), the Oak Ridge National Laboratory (ORNL), and Wharton Econometric Forecasting Associates (WEFA). Leased models are not abstracted here. The directory is intended for the use of energy and energy-policy analysts in the public and private sectors.

  14. 2013 SYR Accepted Poster Abstracts.

    PubMed

    2013-01-01

    SYR 2013 Accepted Poster abstracts: 1. Benefits of Yoga as a Wellness Practice in a Veterans Affairs (VA) Health Care Setting: If You Build It, Will They Come? 2. Yoga-based Psychotherapy Group With Urban Youth Exposed to Trauma. 3. Embodied Health: The Effects of a Mind�Body Course for Medical Students. 4. Interoceptive Awareness and Vegetable Intake After a Yoga and Stress Management Intervention. 5. Yoga Reduces Performance Anxiety in Adolescent Musicians. 6. Designing and Implementing a Therapeutic Yoga Program for Older Women With Knee Osteoarthritis. 7. Yoga and Life Skills Eating Disorder Prevention Among 5th Grade Females: A Controlled Trial. 8. A Randomized, Controlled Trial Comparing the Impact of Yoga and Physical Education on the Emotional and Behavioral Functioning of Middle School Children. 9. Feasibility of a Multisite, Community based Randomized Study of Yoga and Wellness Education for Women With Breast Cancer Undergoing Chemotherapy. 10. A Delphi Study for the Development of Protocol Guidelines for Yoga Interventions in Mental Health. 11. Impact Investigation of Breathwalk Daily Practice: Canada�India Collaborative Study. 12. Yoga Improves Distress, Fatigue, and Insomnia in Older Veteran Cancer Survivors: Results of a Pilot Study. 13. Assessment of Kundalini Mantra and Meditation as an Adjunctive Treatment With Mental Health Consumers. 14. Kundalini Yoga Therapy Versus Cognitive Behavior Therapy for Generalized Anxiety Disorder and Co-Occurring Mood Disorder. 15. Baseline Differences in Women Versus Men Initiating Yoga Programs to Aid Smoking Cessation: Quitting in Balance Versus QuitStrong. 16. Pranayam Practice: Impact on Focus and Everyday Life of Work and Relationships. 17. Participation in a Tailored Yoga Program is Associated With Improved Physical Health in Persons With Arthritis. 18. Effects of Yoga on Blood Pressure: Systematic Review and Meta-analysis. 19. A Quasi-experimental Trial of a Yoga based Intervention to Reduce Stress and

  15. Operating System Abstraction Layer (OSAL)

    NASA Technical Reports Server (NTRS)

    Yanchik, Nicholas J.

    2007-01-01

    This viewgraph presentation reviews the concept of the Operating System Abstraction Layer (OSAL) and its benefits. The OSAL is A small layer of software that allows programs to run on many different operating systems and hardware platforms It runs independent of the underlying OS & hardware and it is self-contained. The benefits of OSAL are that it removes dependencies from any one operating system, promotes portable, reusable flight software. It allows for Core Flight software (FSW) to be built for multiple processors and operating systems. The presentation discusses the functionality, the various OSAL releases, and describes the specifications.

  16. Eggen Card Project: Progress and Plans (Abstract)

    NASA Astrophysics Data System (ADS)

    Silvis, G.

    2016-12-01

    (Abstract only) The Eggen Card Project has been running since 2009 and has involved 30+ AAVSO staff and volunteers. Let me offer a short review of the project, our progress this year and our plans for the future. Phase 1 of the project has been to index the 108,000 card images, identifying the stars they belong too. We've passed the 75% point on this phase. The next phase is how to use this data. Jack Crast has identified the photometric schemes used by Olin and developed a spreadsheet tool to prepare this data for inclusion into the AAVSO International Database (AID). Anyone want good photometry from 1970? We got it!

  17. Abstraction of Seepage into Drifts

    SciTech Connect

    M.L. Wilson; C.K. Ho

    2000-09-26

    A total-system performance assessment (TSPA) for a potential nuclear-waste repository requires an estimate of the amount of water that might contact waste. This paper describes the model used for part of that estimation in a recent TSPA for the Yucca Mountain site. The discussion is limited to estimation of how much water might enter emplacement drifts; additional considerations related to flow within the drifts, and how much water might actually contact waste, are not addressed here. The unsaturated zone at Yucca Mountain is being considered for the potential repository, and a drift opening in unsaturated rock tends to act as a capillary barrier and divert much of the percolating water around it. For TSPA, the important questions regarding seepage are how many waste packages might be subjected to water flow and how much flow those packages might see. Because of heterogeneity of the rock and uncertainty about the future (how the climate will evolve, etc.), it is not possible to predict seepage amounts or locations with certainty. Thus, seepage is treated as a stochastic quantity in TSPA simulations, with the magnitude and spatial distribution of seepage sampled from uncertainty distributions. The distillation of the essential components of process modeling into a form suitable for use in TSPA simulations is referred to as abstraction. In the following sections, seepage process models and abstractions will be summarized and then some illustrative results are presented.

  18. Abstract art by shape classification.

    PubMed

    Song, Yi-Zhe; Pickup, David; Li, Chuan; Rosin, Paul; Hall, Peter

    2013-08-01

    This paper shows that classifying shapes is a tool useful in nonphotorealistic rendering (NPR) from photographs. Our classifier inputs regions from an image segmentation hierarchy and outputs the "best" fitting simple shape such as a circle, square, or triangle. Other approaches to NPR have recognized the benefits of segmentation, but none have classified the shape of segments. By doing so, we can create artwork of a more abstract nature, emulating the style of modern artists such as Matisse and other artists who favored shape simplification in their artwork. The classifier chooses the shape that "best" represents the region. Since the classifier is trained by a user, the "best shape" has a subjective quality that can over-ride measurements such as minimum error and more importantly captures user preferences. Once trained, the system is fully automatic, although simple user interaction is also possible to allow for differences in individual tastes. A gallery of results shows how this classifier contributes to NPR from images by producing abstract artwork.

  19. Experience with abstract notation one

    NASA Technical Reports Server (NTRS)

    Harvey, James D.; Weaver, Alfred C.

    1990-01-01

    The development of computer science has produced a vast number of machine architectures, programming languages, and compiler technologies. The cross product of these three characteristics defines the spectrum of previous and present data representation methodologies. With regard to computer networks, the uniqueness of these methodologies presents an obstacle when disparate host environments are to be interconnected. Interoperability within a heterogeneous network relies upon the establishment of data representation commonality. The International Standards Organization (ISO) is currently developing the abstract syntax notation one standard (ASN.1) and the basic encoding rules standard (BER) that collectively address this problem. When used within the presentation layer of the open systems interconnection reference model, these two standards provide the data representation commonality required to facilitate interoperability. The details of a compiler that was built to automate the use of ASN.1 and BER are described. From this experience, insights into both standards are given and potential problems relating to this development effort are discussed.

  20. Rate and predictors of the conversion of abstracts presented at the Canadian Cardiovascular Congress scientific meetings to full peer-reviewed publications.

    PubMed

    Abuzeid, Wael; Fosbøl, Emil L; Fosbøl, Philip L; Fosbøl, Marie; Zarinehbaf, Sanaz; Ross, Heather; Ko, Dennis T; Bennell, Maria C; Wijeysundera, Harindra C

    2013-11-01

    The rate of conversion of abstracts presented at scientific meetings into peer-reviewed published manuscripts is an important metric for medical societies, because it facilitates translation of scientific knowledge into practice. We determined the rate and predictors of conversion of scientific abstracts presented at the Canadian Cardiovascular Congress (CCC) from 2006 to 2010 into peer-reviewed article publications within 2 years of their initial presentation. Using a previously validated computer algorithm, we searched the International Statistical Institute Web of Science to identify peer-reviewed full manuscript publications of these abstracts. A multivariable logistic regression was used to identify independent factors associated with successful publication. From 2006 to 2010, 3565 abstracts were presented at the CCC. Overall 24.1% of presented abstracts were published within 2 years of the conference. Mean impact factor for publications was 5.2 (range, 0.4-53.2). The type of presentation (for poster vs oral; odds ratio, 0.71; 95% confidence interval, 0.60-0.83; P < 0.001) and category of presentation (P < 0.001) were significantly associated with successful publication. Late breaking abstracts and those related to cancer and clinical sciences were more likely to be published, compared with prevention, vascular biology, and pediatrics. In conclusion, the publication rate at the CCC is only marginally lower than that reported for large international North American and European cardiology conferences (30.6%). Efforts should focus on several identified barriers to improve conversion of abstracts to full report publication.

  1. Compendium of Abstracts. Volume 2

    DTIC Science & Technology

    2010-08-01

    be easily verified. This knowledge could be useful for designing better alkaline membrane and ionomer materials to advance AEFC technology. I wish...Litz. 6 Reaction of Certain Aluminum Based Intermetallic Forming Materials Aydelotte, Brady B. I studied the mechanics of impact initiation of...microscopy (SEM) of the failure surfaces of the materials . Differences in the microstructure at fine length scales suggest a possible explanation for

  2. Low-level radioactive waste from commercial nuclear reactors. Volume 3. Bibliographic abstracts of significant source documents. Part 1. Open-literature abstracts for low-level radioactive waste

    SciTech Connect

    Bowers, M.K.; Rodgers, B.R.; Jolley, R.L.

    1986-05-01

    The overall task of this program was to provide an assessment of currently available technology for treating commercial low-level radioactive waste (LLRW), to initiate development of a methodology for choosing one technology for a given application, and to identify research needed to improve current treatment techniques and decision methodology. The resulting report is issued in four volumes. Volume 3 of this series is a collection of abstracts of most of the reference documents used for this study. Because of the large volume of literature, the abstracts have been printed in two separate parts. Volume 3, part 1 presents abstracts of the open literature relating to LLRW treatment methodologies. Some of these references pertain to treatment processes for hazardous wastes that may also be applicable to LLRW management. All abstracts have been limited to 21 lines (for brevity), but each abstract contains sufficient information to enable the reader to determine the potential usefulness of the source document and to locate each article. The abstracts are arranged alphabetically by author or organization, and indexed by keyword.

  3. Ozone Conference II: Abstract Proceedings

    SciTech Connect

    1999-11-01

    Ozone Conference II: Pre- and Post-Harvest Applications Two Years After Gras, was held September 27-28, 1999 in Tulare, California. This conference, sponsored by EPRI's Agricultural Technology Alliance and Southern California Edison's AgTAC facility, was coordinated and organized by the on-site ATA-AgTAC Regional Center. Approximately 175 people attended the day-and-a-half conference at AgTAC. During the Conference twenty-two presentations were given on ozone food processing and agricultural applications. Included in the presentations were topics on: (1) Ozone fumigation; (2) Ozone generation techniques; (3) System and design applications; (4) Prewater treatment requirements; (5) Poultry water reuse; (6) Soil treatments with ozone gas; and (7) Post-harvest aqueous and gaseous ozone research results. A live videoconference between Tulare and Washington, D.C. was held to discuss the regulators' view from inside the beltway. Attendees participated in two Roundtable Question and Answer sessions and visited fifteen exhibits and demonstrations. The attendees included university and governmental researchers, regulators, consultants and industry experts, technology developers and providers, and corporate and individual end-users. This report is comprised of the Abstracts of each presentation, biographical sketches for each speaker and a registration/attendees list.

  4. SLAS Library Telescope Program (Abstract)

    NASA Astrophysics Data System (ADS)

    Small, J. S.

    2016-12-01

    (Abstract only) In the fall of 2014, I submitted to the members of the St. Louis Astronomical Society to take the $1,000 profit we had from a convention we had hosted and use it to purchase three telescopes to modify for a Library Telescope program that was invented by Mark Stowbridge and promoted by the New Hampshire Astronomical Society. I had met Mark at NEAF in 2012 when he was walking the floor demonstrating the telescope. We held meetings with three libraries, the St. Louis County Library system, the St. Louis Public Library system and an independent library in Kirkwood, Missouri. The response was overwhelming! SLCL responded with a request for ten telescopes and SLPL asked for five. We did our first build in October, 2014 and placed a total of eighteen telescopes. Since that time, SLAS has placed a total of eighty-eight telescopes in library systems around the St. Louis Metro area, expanding into neighboring counties and across the river in Illinois. In this talk, I will discuss how to approach this project and put it in place in your libraries!

  5. An abstract approach to music.

    SciTech Connect

    Kaper, H. G.; Tipei, S.

    1999-04-19

    In this article we have outlined a formal framework for an abstract approach to music and music composition. The model is formulated in terms of objects that have attributes, obey relationships, and are subject to certain well-defined operations. The motivation for this approach uses traditional terms and concepts of music theory, but the approach itself is formal and uses the language of mathematics. The universal object is an audio wave; partials, sounds, and compositions are special objects, which are placed in a hierarchical order based on time scales. The objects have both static and dynamic attributes. When we realize a composition, we assign values to each of its attributes: a (scalar) value to a static attribute, an envelope and a size to a dynamic attribute. A composition is then a trajectory in the space of aural events, and the complex audio wave is its formal representation. Sounds are fibers in the space of aural events, from which the composer weaves the trajectory of a composition. Each sound object in turn is made up of partials, which are the elementary building blocks of any music composition. The partials evolve on the fastest time scale in the hierarchy of partials, sounds, and compositions. The ideas outlined in this article are being implemented in a digital instrument for additive sound synthesis and in software for music composition. A demonstration of some preliminary results has been submitted by the authors for presentation at the conference.

  6. Handedness shapes children's abstract concepts.

    PubMed

    Casasanto, Daniel; Henetz, Tania

    2012-03-01

    Can children's handedness influence how they represent abstract concepts like kindness and intelligence? Here we show that from an early age, right-handers associate rightward space more strongly with positive ideas and leftward space with negative ideas, but the opposite is true for left-handers. In one experiment, children indicated where on a diagram a preferred toy and a dispreferred toy should go. Right-handers tended to assign the preferred toy to a box on the right and the dispreferred toy to a box on the left. Left-handers showed the opposite pattern. In a second experiment, children judged which of two cartoon animals looked smarter (or dumber) or nicer (or meaner). Right-handers attributed more positive qualities to animals on the right, but left-handers to animals on the left. These contrasting associations between space and valence cannot be explained by exposure to language or cultural conventions, which consistently link right with good. Rather, right- and left-handers implicitly associated positive valence more strongly with the side of space on which they can act more fluently with their dominant hands. Results support the body-specificity hypothesis (Casasanto, 2009), showing that children with different kinds of bodies think differently in corresponding ways.

  7. Attracting Girls into Physics (abstract)

    NASA Astrophysics Data System (ADS)

    Gadalla, Afaf

    2009-04-01

    A recent international study of women in physics showed that enrollment in physics and science is declining for both males and females and that women are severely underrepresented in careers requiring a strong physics background. The gender gap begins early in the pipeline, from the first grade. Girls are treated differently than boys at home and in society in ways that often hinder their chances for success. They have fewer freedoms, are discouraged from accessing resources or being adventurous, have far less exposure to problem solving, and are not encouraged to choose their lives. In order to motivate more girl students to study physics in the Assiut governorate of Egypt, the Assiut Alliance for the Women and Assiut Education District collaborated in renovating the education of physics in middle and secondary school classrooms. A program that helps in increasing the number of girls in science and physics has been designed in which informal groupings are organized at middle and secondary schools to involve girls in the training and experiences needed to attract and encourage girls to learn physics. During implementation of the program at some schools, girls, because they had not been trained in problem-solving as boys, appeared not to be as facile in abstracting the ideas of physics, and that was the primary reason for girls dropping out of science and physics. This could be overcome by holding a topical physics and technology summer school under the supervision of the Assiut Alliance for the Women.

  8. Annotating user-defined abstractions for optimization

    SciTech Connect

    Quinlan, D; Schordan, M; Vuduc, R; Yi, Q

    2005-12-05

    This paper discusses the features of an annotation language that we believe to be essential for optimizing user-defined abstractions. These features should capture semantics of function, data, and object-oriented abstractions, express abstraction equivalence (e.g., a class represents an array abstraction), and permit extension of traditional compiler optimizations to user-defined abstractions. Our future work will include developing a comprehensive annotation language for describing the semantics of general object-oriented abstractions, as well as automatically verifying and inferring the annotated semantics.

  9. Abstraction and reformulation in artificial intelligence.

    PubMed Central

    Holte, Robert C.; Choueiry, Berthe Y.

    2003-01-01

    This paper contributes in two ways to the aims of this special issue on abstraction. The first is to show that there are compelling reasons motivating the use of abstraction in the purely computational realm of artificial intelligence. The second is to contribute to the overall discussion of the nature of abstraction by providing examples of the abstraction processes currently used in artificial intelligence. Although each type of abstraction is specific to a somewhat narrow context, it is hoped that collectively they illustrate the richness and variety of abstraction in its fullest sense. PMID:12903653

  10. Core foundations of abstract geometry.

    PubMed

    Dillon, Moira R; Huang, Yi; Spelke, Elizabeth S

    2013-08-27

    Human adults from diverse cultures share intuitions about the points, lines, and figures of Euclidean geometry. Do children develop these intuitions by drawing on phylogenetically ancient and developmentally precocious geometric representations that guide their navigation and their analysis of object shape? In what way might these early-arising representations support later-developing Euclidean intuitions? To approach these questions, we investigated the relations among young children's use of geometry in tasks assessing: navigation; visual form analysis; and the interpretation of symbolic, purely geometric maps. Children's navigation depended on the distance and directional relations of the surface layout and predicted their use of a symbolic map with targets designated by surface distances. In contrast, children's analysis of visual forms depended on the size-invariant shape relations of objects and predicted their use of the same map but with targets designated by corner angles. Even though the two map tasks used identical instructions and map displays, children's performance on these tasks showed no evidence of integrated representations of distance and angle. Instead, young children flexibly recruited geometric representations of either navigable layouts or objects to interpret the same spatial symbols. These findings reveal a link between the early-arising geometric representations that humans share with diverse animals and the flexible geometric intuitions that give rise to human knowledge at its highest reaches. Although young children do not appear to integrate core geometric representations, children's use of the abstract geometry in spatial symbols such as maps may provide the earliest clues to the later construction of Euclidean geometry.

  11. Phage display biopanning identifies the translation initiation and elongation factors (IF1α-3 and eIF-3) as components of Hsp70-peptide complexes in breast tumour cells.

    PubMed

    Siebke, Christina; James, Tharappel C; Cummins, Robert; O'Grady, Tony; Kay, Elaine; Bond, Ursula

    2012-03-01

    The heat shock protein, HSP70, is over-expressed in many tumours and acts at the crossroads of key intracellular processes in its role as a molecular chaperone. HSP70 associates with a vast array of peptides, some of which are antigenic and can mount adaptive immune responses against the tumour from which they are derived. The pool of peptides associated with HSP70 represents a unique barcode of protein metabolism in tumour cells. With a view to identifying unique protein targets that may be developed as tumour biomarkers, we used purified HSP70 and its associated peptide pool (HSP70-peptide complexes, HSP70-PCs) from different human breast tumour cell lines as targets for phage display biopanning. Our results show that HSP70-PCs from each cell line interact with unique sets of peptides within the phage display library. One of the peptides, termed IST, enriched in the biopanning process, was used in a 'pull-down' assay to identify the original protein from which the HSP70-associated peptides may have been derived. The eukaryotic translation initiation factor 3 (eIF-3), a member of the elongation factor EF1α family, and the HSP GRP78, were pulled down by the IST peptide. All of these proteins are known to be up-regulated in cancer cells. Immunohistochemical staining of tumour tissue microarrays showed that the peptide co-localised with HSP70 in breast tumour tissue. The data indicate that the reservoir of peptides associated with HSP70 can act as a unique indicator of cellular protein activity and a novel source of potential tumour biomarkers.

  12. Abstract and concrete concepts have structurally different representational frameworks.

    PubMed

    Crutch, Sebastian J; Warrington, Elizabeth K

    2005-03-01

    The architecture supporting our conceptual knowledge of abstract words has remained almost entirely unexplored. By contrast, a vast neuropsychological, neurolinguistic and neuroimaging literature has addressed questions relating to the structure of the semantic system underpinning our knowledge of concrete items (e.g. artefacts and animals). In the context of semantic refractory access dysphasia, a series of experiments exploring and comparing abstract and concrete word comprehension are described. We demonstrate that semantically associated abstract words reliably interfere with one another significantly more than semantically synonymous abstract words, while concrete words show the reverse pattern. We report the first evidence that abstract and concrete word meanings are based in representational systems that have qualitatively different properties. More specifically, we show that abstract concepts, but not concrete concepts, are represented in an associative neural network. Furthermore, our patient was found to have significantly greater difficulty in identifying high frequency than low frequency abstract words. This observation constitutes the first evidence of an inverse word frequency effect. Our results challenge the generality of many existing models of human conceptual knowledge, which derive their structure from experimental findings in the concrete domain alone.

  13. 37 CFR 1.438 - The abstract.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false The abstract. 1.438 Section 1... COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES International Processing Provisions The International Application § 1.438 The abstract. (a) Requirements as to the content and form of the abstract are set forth...

  14. EDUCATIONAL MEDIA RESEARCH ABSTRACTING PROJECT. FINAL REPORT.

    ERIC Educational Resources Information Center

    HYER, ANNA L.

    THIS PROJECT PROVIDED ABSTRACTING COVERAGE OF 33 FINAL REPORTS OF U.S. OFFICE OF EDUCATION FINANCED RESEARCH PROJECTS IN EDUCATIONAL MEDIA. AN ABSTRACTOR, DR. WILLIAM ALLEN, WAS HIRED TO EVALUATE AND EDIT OR REWRITE ABSTRACTS SUBMITTED BY RESEARCHERS, AND TO PREPARE ABSTRACTS IF NECESSARY. TWO ANALYTICAL REVIEWS ON SELECTED AREAS OF MEDIA RESEARCH…

  15. Writing a Structured Abstract for the Thesis

    ERIC Educational Resources Information Center

    Hartley, James

    2010-01-01

    This article presents the author's suggestions on how to improve thesis abstracts. The author describes two books on writing abstracts: (1) "Creating Effective Conference Abstracts and Posters in Biomedicine: 500 tips for Success" (Fraser, Fuller & Hutber, 2009), a compendium of clear advice--a must book to have in one's hand as one prepares a…

  16. At the HeART of Abstraction

    ERIC Educational Resources Information Center

    Berdit, Nancy

    2006-01-01

    Abstraction has long been a concept difficult to define for students. Students often feel the pressure of making their artwork "look real" and frustration can often lead to burnout in the classroom. In this article, the author describes how her lesson on abstraction has alleviated much of that pressure as students created an abstract acrylic…

  17. 37 CFR 1.438 - The abstract.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false The abstract. 1.438 Section 1... COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES International Processing Provisions The International Application § 1.438 The abstract. (a) Requirements as to the content and form of the abstract are set forth...

  18. 37 CFR 1.438 - The abstract.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2012-07-01 2012-07-01 false The abstract. 1.438 Section 1... COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES International Processing Provisions The International Application § 1.438 The abstract. (a) Requirements as to the content and form of the abstract are set forth...

  19. 37 CFR 1.438 - The abstract.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2013-07-01 2013-07-01 false The abstract. 1.438 Section 1... COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES International Processing Provisions The International Application § 1.438 The abstract. (a) Requirements as to the content and form of the abstract are set forth...

  20. Abstract Context Representations in Primate Amygdala and Prefrontal Cortex.

    PubMed

    Saez, A; Rigotti, M; Ostojic, S; Fusi, S; Salzman, C D

    2015-08-19

    Neurons in prefrontal cortex (PFC) encode rules, goals, and other abstract information thought to underlie cognitive, emotional, and behavioral flexibility. Here we show that the amygdala, a brain area traditionally thought to mediate emotions, also encodes abstract information that could underlie this flexibility. Monkeys performed a task in which stimulus-reinforcement contingencies varied between two sets of associations, each defining a context. Reinforcement prediction required identifying a stimulus and knowing the current context. Behavioral evidence indicated that monkeys utilized this information to perform inference and adjust their behavior. Neural representations in both amygdala and PFC reflected the linked sets of associations implicitly defining each context, a process requiring a level of abstraction characteristic of cognitive operations. Surprisingly, when errors were made, the context signal weakened substantially in the amygdala. These data emphasize the importance of maintaining abstract cognitive information in the amygdala to support flexible behavior.

  1. Mining Heterogeneous Social Networks for Egocentric Information Abstraction

    NASA Astrophysics Data System (ADS)

    Li, Cheng-Te; Lin, Shou-De

    Social network is a powerful data structure that allows the depiction of relationship information between entities. However, real-world social networks are sometimes too complex for human to pursue further analysis. In this work, an unsupervised mechanism is proposed for egocentric information abstraction in heterogeneous social networks. To achieve this goal, we propose a vector space representation for heterogeneous social networks to identify combination of relations as features and compute statistical dependencies as feature values. These features, either linear or eyelie, intend to capture the semantic information in the surrounding environment of the ego. Then we design three abstraction measures to distill representative and important information to construct the abstracted graphs for visual presentation. The evaluations conducted on a real world movie datasct and an artificial crime dataset demonstrate that the abstractions can indeed retain significant information and facilitate more accurate and efficient human analysis.

  2. Abstract models of molecular walkers

    NASA Astrophysics Data System (ADS)

    Semenov, Oleg

    Recent advances in single-molecule chemistry have led to designs for artificial multi-pedal walkers that follow tracks of chemicals. The walkers, called molecular spiders, consist of a rigid chemically inert body and several flexible enzymatic legs. The legs can reversibly bind to chemical substrates on a surface, and through their enzymatic action convert them to products. We study abstract models of molecular spiders to evaluate how efficiently they can perform two tasks: molecular transport of cargo over tracks and search for targets on finite surfaces. For the single-spider model our simulations show a transient behavior wherein certain spiders move superdiffusively over significant distances and times. This gives the spiders potential as a faster-than-diffusion transport mechanism. However, analysis shows that single-spider motion eventually decays into an ordinary diffusive motion, owing to the ever increasing size of the region of products. Inspired by cooperative behavior of natural molecular walkers, we propose a symmetric exclusion process (SEP) model for multiple walkers interacting as they move over a one-dimensional lattice. We show that when walkers are sequentially released from the origin, the collective effect is to prevent the leading walkers from moving too far backwards. Hence, there is an effective outward pressure on the leading walkers that keeps them moving superdiffusively for longer times. Despite this improvement the leading spider eventually slows down and moves diffusively, similarly to a single spider. The slowdown happens because all spiders behind the leading spiders never encounter substrates, and thus they are never biased. They cannot keep up with leading spiders, and cannot put enough pressure on them. Next, we investigate search properties of a single and multiple spiders moving over one- and two-dimensional surfaces with various absorbing and reflecting boundaries. For the single-spider model we evaluate by how much the

  3. Identifying Hazards

    EPA Pesticide Factsheets

    The federal government has established a system of labeling hazardous materials to help identify the type of material and threat posed. Summaries of information on over 300 chemicals are maintained in the Envirofacts Master Chemical Integrator.

  4. Research & writing basics: elements of the abstract.

    PubMed

    Krasner, D; Van Rijswijk, L

    1995-04-01

    Writing an abstract is a challenging skill that requires precision and care. Criteria for well-formulated abstracts and abstract guidelines for 2 types of articles (empirical studies and reviews or theoretical articles) as well as a description of the content of a structured abstract are presented. Details were gleaned from a review of the literature including the American Medical Association Manual of Style, Eighth Edition and the Publication Manual of the American Psychological Association, Fourth Edition. A good abstract is like a crystal: it is a clear, sharp synthesis that elucidates meaning for the reader.

  5. Abstract thinking following severe traumatic brain injury.

    PubMed

    Scherzer, B P; Charbonneau, S; Solomon, C R; Lepore, F

    1993-01-01

    Abstract abilities were studied in a sample of 34 individuals with severe TBI and a control group. The results indicate that TBI interferes with performance on tests requiring individuals to process information into new categories. There appears to be a dissociation between verbal abstract abilities and visual-perceptual abstract abilities. There is evidence that Goldstein and Sheerer's [1] postulate of a general 'abstract attitude' was at least partially correct. This attitude does not appear to be related to a general verbal ideational process, as dysphasic subjects were only deficient on a purely verbal abstract task.

  6. CD49f and CD61 identify Her2/neu-induced mammary tumor initiating cells that are potentially derived from luminal progenitors and maintained by the integrin-TGFβ signaling

    PubMed Central

    Lo, Pang-Kuo; Kanojia, Deepak; Liu, Xinfeng; Singh, Udai P.; Berger, Franklin G.; Wang, Qian; Chen, Hexin

    2011-01-01

    HER2/Neu is overexpressed in 20-30% of breast cancers and associated with aggressive phenotypes and poor prognosis. For deciphering the role of HER2/Neu in breast cancer, mouse mammary tumor virus (MMTV)-Her2/neu transgenic mice that develop mammary tumors resembling human HER2-subtype breast cancer have been established. Several recent studies have revealed that HER2/Neu is overexpressed in and regulates self renewal of breast tumor initiating cells (TICs). However, in the MMTV-Her2/neu transgenic mouse model, the identity of TICs remains elusive, despite previous studies showing supportive evidence for existence of TICs in Her2/neu-induced mammary tumors. Through systematic screening and characterization, we identified surface markers CD49f, CD61 and ESA were aberrantly overexpressed in Her2-overexpressing mammary tumor cells. Analysis of these markers as well as CD24 detected anomalous expansion of the luminal progenitor population in preneoplastic mammary glands of Her2/neu-transgenic mice, indicating that aberrant luminal progenitors originated Her2-induced mammary tumors. The combined markers, CD49f and CD61, further delineated the CD49fhighCD61high-sorted fraction as a TIC-enriched population, which displayed increased tumorsphere formation ability, enhanced tumorigenicity both in vitro and in vivo and drug resistance to pacitaxel and doxorubicin. Moreover, the TIC-enriched population manifested increased TGFβ signaling and exhibited gene expression signatures of stemness, TGFβ signaling and Epithelial-to-Mesenchymal Transition. Our findings that self-renewal and clonogenicity of TICs were suppressed by pharmacologically inhibiting the TGFβ signaling further indicate that the TGFβ pathway is vital for maintenance of the TIC population. Finally, we showed that the integrin β3 (CD61) signaling pathway was required for sustaining active TGFβ signaling and self-renewal of TICs. We for the first time developed a technique to highly enrich TICs from mammary

  7. Abstracted Workow Framework with a Structure from Motion Application

    NASA Astrophysics Data System (ADS)

    Rossi, Adam J.

    In scientific and engineering disciplines, from academia to industry, there is an increasing need for the development of custom software to perform experiments, construct systems, and develop products. The natural mindset initially is to shortcut and bypass all overhead and process rigor in order to obtain an immediate result for the problem at hand, with the misconception that the software will simply be thrown away at the end. In a majority of the cases, it turns out the software persists for many years, and likely ends up in production systems for which it was not initially intended. In the current study, a framework that can be used in both industry and academic applications mitigates underlying problems associated with developing scientific and engineering software. This results in software that is much more maintainable, documented, and usable by others, specifically allowing new users to extend capabilities of components already implemented in the framework. There is a multi-disciplinary need in the fields of imaging science, computer science, and software engineering for a unified implementation model, which motivates the development of an abstracted software framework. Structure from motion (SfM) has been identified as one use case where the abstracted workflow framework can improve research efficiencies and eliminate implementation redundancies in scientific fields. The SfM process begins by obtaining 2D images of a scene from different perspectives. Features from the images are extracted and correspondences are established. This provides a sufficient amount of information to initialize the problem for fully automated processing. Transformations are established between views, and 3D points are established via triangulation algorithms. The parameters for the camera models for all views / images are solved through bundle adjustment, establishing a highly consistent point cloud. The initial sparse point cloud and camera matrices are used to generate a dense

  8. Chemical Abstracts Service Chemical Registry System: History, Scope, and Impacts.

    ERIC Educational Resources Information Center

    Weisgerber, David W.

    1997-01-01

    Describes the history, scope, and applications of the Chemical Abstracts Service Chemical Registry System, a computerized database that uniquely identifies chemical substances on the basis of their molecular structures. Explains searching the system is and discusses its use as an international resource. (66 references) (Author/LRW)

  9. Intern Abstract for Spring 2016

    NASA Technical Reports Server (NTRS)

    Gibson, William

    2016-01-01

    The Human Interface Branch - EV3 - is evaluating Organic lighting-emitting diodes (OLEDs) as an upgrade for current displays on future spacecraft. OLEDs have many advantages over current displays. Conventional displays require constant backlighting which draws a lot of power, but with OLEDs they generate light themselves. OLEDs are lighter, and weight is always a concern with space launches. OLEDs also grant greater viewing angles. OLEDs have been in the commercial market for almost ten years now. What is not known is how they will perform in a space-like environment; specifically deep space far away from the Earth's magnetosphere. In this environment, the OLEDs can be expected to experience vacuum and galactic radiation. The intern's responsibility has been to prepare the OLED for a battery of tests. Unfortunately, it will not be ready for testing at the end of the internship. That being said much progress has been made: a) Developed procedures to safely disassemble the tablet. b) Inventoried and identified critical electronic components. c) 3D printed a testing apparatus. d) Wrote software in Python that will test the OLED screen while being radiated. e) Built circuits to restart the tablet and the test pattern, and ensure it doesn't fall asleep during radiation testing. f) Built enclosure that will house all of the electronics Also, the intern has been working on a way to take messages from a simulated Caution and Warnings system, process said messages into packets, send audio packets to a multicast address that audio boxes are listening to, and output spoken audio. Currently, Cautions and Warnings use a tone to alert crew members of a situation, and then crew members have to read through their checklists to determine what the tone means. In urgent situations, EV3 wants to deliver concise and specific alerts to the crew to facilitate any mitigation efforts on their part. Significant progress was made on this project: a) Open channel with the simulated Caution

  10. Writing an abstract for a scientific conference.

    PubMed

    Simkhada, P; van Teijlingen, E; Hundley, V; Simkhada, B D

    2013-01-01

    For most students and junior researchers, writing an abstract for a poster or oral presentation at a conference is the first piece they may write for an audience other than their university tutors or examiners. Since some researchers struggle with this process we have put together some advice on issues to consider when writing a conference abstract. We highlight a number of issues to bear in mind when constructing one's abstract.

  11. Factors Affecting Accuracy of Data Abstracted from Medical Records

    PubMed Central

    Zozus, Meredith N.; Pieper, Carl; Johnson, Constance M.; Johnson, Todd R.; Franklin, Amy; Smith, Jack; Zhang, Jiajie

    2015-01-01

    Objective Medical record abstraction (MRA) is often cited as a significant source of error in research data, yet MRA methodology has rarely been the subject of investigation. Lack of a common framework has hindered application of the extant literature in practice, and, until now, there were no evidence-based guidelines for ensuring data quality in MRA. We aimed to identify the factors affecting the accuracy of data abstracted from medical records and to generate a framework for data quality assurance and control in MRA. Methods Candidate factors were identified from published reports of MRA. Content validity of the top candidate factors was assessed via a four-round two-group Delphi process with expert abstractors with experience in clinical research, registries, and quality improvement. The resulting coded factors were categorized into a control theory-based framework of MRA. Coverage of the framework was evaluated using the recent published literature. Results Analysis of the identified articles yielded 292 unique factors that affect the accuracy of abstracted data. Delphi processes overall refuted three of the top factors identified from the literature based on importance and five based on reliability (six total factors refuted). Four new factors were identified by the Delphi. The generated framework demonstrated comprehensive coverage. Significant underreporting of MRA methodology in recent studies was discovered. Conclusion The framework generated from this research provides a guide for planning data quality assurance and control for studies using MRA. The large number and variability of factors indicate that while prospective quality assurance likely increases the accuracy of abstracted data, monitoring the accuracy during the abstraction process is also required. Recent studies reporting research results based on MRA rarely reported data quality assurance or control measures, and even less frequently reported data quality metrics with research results. Given

  12. A brief on writing a successful abstract.

    PubMed

    Gambescia, Stephen F

    2013-01-01

    The abstract for an article submitted to a clinical or academic journal often gets little attention in the manuscript preparation process. The abstract serves multiple purposes in scholarly work dissemination, including the one piece of information reviewers have to invite presenters to professional conferences. Therefore, the abstract can be the most important and should be the most powerful 150-250 words written by authors of scholarly work. This brief for healthcare practitioners, junior faculty, and students provides general comments, details, nuances and tips and explains the various uses of the abstract for publications and presentations in the healthcare field.

  13. Third LDEF Post-Retrieval Symposium Abstracts

    NASA Technical Reports Server (NTRS)

    Levine, Arlene S. (Compiler)

    1993-01-01

    This volume is a compilation of abstracts submitted to the Third Long Duration Exposure Facility (LDEF) Post-Retrieval Symposium. The abstracts represent the data analysis of the 57 experiments flown on the LDEF. The experiments include materials, coatings, thermal systems, power and propulsion, science (cosmic ray, interstellar gas, heavy ions, micrometeoroid, etc.), electronics, optics, and life science.

  14. New Features in the ADS Abstract Service

    NASA Technical Reports Server (NTRS)

    Eichhorn, Guenther; Accomazzi, Alberto; Grant, Carolyn S.; Kurtz, Michael J.; Henneken, Edwin A.; Thompson, Donna M.; Murray, Stephen S.

    2005-01-01

    The NASA-ADS Abstract Service provides a sophisticated search capability for the literature in Astronomy, Planetary Sciences, Physics/Geophysics, and Space Instrumentation. The ADS is funded by NASA and access to the ADS services is free to anybody world-wide without restrictions. It allows the user to search the literature by author, title, and abstract text.

  15. Developing Creativity and Abstraction in Representing Data

    ERIC Educational Resources Information Center

    South, Andy

    2012-01-01

    Creating charts and graphs is all about visual abstraction: the process of representing aspects of data with imagery that can be interpreted by the reader. Children may need help making the link between the "real" and the image. This abstraction can be achieved using symbols, size, colour and position. Where the representation is close to what…

  16. Title I, Higher Education Act Program Abstracts.

    ERIC Educational Resources Information Center

    Miller, Lorna M., Ed.

    The 1979 edition of the Title I, Higher Education Act Program Abstracts is presented. Directed toward state Title I, HEA administrators, the program abstracts are made available in order to encourage nationwide program replication of those tested and evaluated programs that have been conducted with Title I support by institutions of higher…

  17. Tour the Galaxy of the Abstract.

    ERIC Educational Resources Information Center

    Kennedy, Patricia

    2003-01-01

    Describes an abstract art unit in which students in an introductory art course created abstract art inspired by the work of M. C. Escher. Explains that some students are unsure of their drawing ability. States this unit helps them overcome their fears. (CMK)

  18. Abstracts of Selected Management Training Evaluations.

    ERIC Educational Resources Information Center

    Gast, Ilene

    Intended for evaluators--whether trainers, psychologists, management consultants or professors--this bibliography samples findings in management training evaluation between 1953 and 1975. It contains 28 abstracts of representative articles from journals in applied psychology and personnel management. Each abstract is a one-half to one-page…

  19. Interactional Metadiscourse in Research Article Abstracts

    ERIC Educational Resources Information Center

    Gillaerts, Paul; Van de Velde, Freek

    2010-01-01

    This paper deals with interpersonality in research article abstracts analysed in terms of interactional metadiscourse. The evolution in the distribution of three prominent interactional markers comprised in Hyland's (2005a) model, viz. hedges, boosters and attitude markers, is investigated in three decades of abstract writing in the field of…

  20. Foundations of the Bandera Abstraction Tools

    NASA Technical Reports Server (NTRS)

    Hatcliff, John; Dwyer, Matthew B.; Pasareanu, Corina S.; Robby

    2003-01-01

    Current research is demonstrating that model-checking and other forms of automated finite-state verification can be effective for checking properties of software systems. Due to the exponential costs associated with model-checking, multiple forms of abstraction are often necessary to obtain system models that are tractable for automated checking. The Bandera Tool Set provides multiple forms of automated support for compiling concurrent Java software systems to models that can be supplied to several different model-checking tools. In this paper, we describe the foundations of Bandera's data abstraction mechanism which is used to reduce the cardinality (and the program's state-space) of data domains in software to be model-checked. From a technical standpoint, the form of data abstraction used in Bandera is simple, and it is based on classical presentations of abstract interpretation. We describe the mechanisms that Bandera provides for declaring abstractions, for attaching abstractions to programs, and for generating abstracted programs and properties. The contributions of this work are the design and implementation of various forms of tool support required for effective application of data abstraction to software components written in a programming language like Java which has a rich set of linguistic features.

  1. Discourse-Level Structure in Abstracts.

    ERIC Educational Resources Information Center

    Liddy, Elizabeth D.

    An investigation was undertaken into the possibility of automatically detecting how concepts exist in relation to each other in abstracts, a text-type commonly used in free-text retrieval. The end goal of this research is to capture these relationships in structured representations of abstracts' contents so that users can require not only that the…

  2. Abstraction and context in concept representation.

    PubMed Central

    Hampton, James A

    2003-01-01

    This paper develops the notion of abstraction in the context of the psychology of concepts, and discusses its relation to context dependence in knowledge representation. Three general approaches to modelling conceptual knowledge from the domain of cognitive psychology are discussed, which serve to illustrate a theoretical dimension of increasing levels of abstraction. PMID:12903660

  3. Dissertation Abstracts in Mathematics Education, 1983.

    ERIC Educational Resources Information Center

    Suydam, Marilyn N., Comp.

    The dissertation abstracts in this compilation all appeared in "Dissertation Abstracts International" in 1983. The 300 dissertations cited in the annual listing of research in the July 1984 issue of the "Journal for Research in Mathematics Education" are included, as well as 55 dissertations which were located but could not be…

  4. Interpreting Abstract Interpretations in Membership Equational Logic

    NASA Technical Reports Server (NTRS)

    Fischer, Bernd; Rosu, Grigore

    2001-01-01

    We present a logical framework in which abstract interpretations can be naturally specified and then verified. Our approach is based on membership equational logic which extends equational logics by membership axioms, asserting that a term has a certain sort. We represent an abstract interpretation as a membership equational logic specification, usually as an overloaded order-sorted signature with membership axioms. It turns out that, for any term, its least sort over this specification corresponds to its most concrete abstract value. Maude implements membership equational logic and provides mechanisms to calculate the least sort of a term efficiently. We first show how Maude can be used to get prototyping of abstract interpretations "for free." Building on the meta-logic facilities of Maude, we further develop a tool that automatically checks and abstract interpretation against a set of user-defined properties. This can be used to select an appropriate abstract interpretation, to characterize the specified loss of information during abstraction, and to compare different abstractions with each other.

  5. Youth Studies Abstracts. Vol. 4 No. 1.

    ERIC Educational Resources Information Center

    Youth Studies Abstracts, 1985

    1985-01-01

    This volume contains abstracts of 76 projects (most of which were conducted in Australia and New Zealand) concerned with programs for youth and with social and educational developments affecting youth. The abstracts are arranged in the following two categories: (1) Social and Educational Developments: Policy, Analysis, Research; and (2) Programs:…

  6. A Microfilm Index to "Chemical Abstracts"

    ERIC Educational Resources Information Center

    Robinson, F.

    1973-01-01

    To improve access to the recent Chemical Abstracts,'' a cumulative quarterly index, based on the keyword phrases, has been produced in microfilm form. The index is available soon after the end of each quarter. Abstract titles are included in the index, thus increasing its value as a working tool. (4 references) (Author/SJ)

  7. Prefrontal Cortex Organization: Dissociating Effects of Temporal Abstraction, Relational Abstraction, and Integration with fMRI

    PubMed Central

    Nee, Derek Evan; Jahn, Andrew; Brown, Joshua W.

    2014-01-01

    The functions of the prefrontal cortex (PFC) underlie higher-level cognition. Varying proposals suggest that the PFC is organized along a rostral-caudal gradient of abstraction with more abstract representations/processes associated with more rostral areas. However, the operational definition of abstraction is unclear. Here, we contrasted 2 prominent theories of abstraction—temporal and relational—using fMRI. We further examined whether integrating abstract rules—a function common to each theory—recruited the PFC independently of other abstraction effects. While robust effects of relational abstraction were present in the PFC, temporal abstraction effects were absent. Instead, we found activations specific to the integration of relational rules in areas previously shown to be associated with temporal abstraction. We suggest that previous effects of temporal abstraction were due to confounds with integration demands. We propose an integration framework to understand the functions of the PFC that resolves discrepancies in prior data. PMID:23563962

  8. Initiation of vascular development.

    PubMed

    Ohashi-Ito, Kyoko; Fukuda, Hiroo

    2014-06-01

    The initiation of vascular development occurs during embryogenesis and the development of lateral organs, such as lateral roots and leaves. Understanding the mechanism underlying the initiation of vascular development has been an important goal of plant biologists. Auxin flow is a crucial factor involved in the initiation of vascular development. In addition, recent studies have identified key factors that regulate the establishment of vascular initial cells in embryos and roots. In this review, we summarize the recent findings in this field and discuss the initiation of vascular development.

  9. Abstract Spatial Reasoning as an Autistic Strength

    PubMed Central

    Stevenson, Jennifer L.; Gernsbacher, Morton Ann

    2013-01-01

    Autistic individuals typically excel on spatial tests that measure abstract reasoning, such as the Block Design subtest on intelligence test batteries and the Raven’s Progressive Matrices nonverbal test of intelligence. Such well-replicated findings suggest that abstract spatial processing is a relative and perhaps absolute strength of autistic individuals. However, previous studies have not systematically varied reasoning level – concrete vs. abstract – and test domain – spatial vs. numerical vs. verbal, which the current study did. Autistic participants (N = 72) and non-autistic participants (N = 72) completed a battery of 12 tests that varied by reasoning level (concrete vs. abstract) and domain (spatial vs. numerical vs. verbal). Autistic participants outperformed non-autistic participants on abstract spatial tests. Non-autistic participants did not outperform autistic participants on any of the three domains (spatial, numerical, and verbal) or at either of the two reasoning levels (concrete and abstract), suggesting similarity in abilities between autistic and non-autistic individuals, with abstract spatial reasoning as an autistic strength. PMID:23533615

  10. Abstract conceptual feature ratings: the role of emotion, magnitude, and other cognitive domains in the organization of abstract conceptual knowledge.

    PubMed

    Crutch, Sebastian J; Troche, Joshua; Reilly, Jamie; Ridgway, Gerard R

    2013-01-01

    This study harnessed control ratings of the contribution of different types of information (sensation, action, emotion, thought, social interaction, morality, time, space, quantity, and polarity) to 400 individual abstract and concrete verbal concepts. These abstract conceptual feature (ACF) ratings were used to generate a high dimensional semantic space, from which Euclidean distance measurements between individual concepts were extracted as a metric of the semantic relatedness of those words. The validity of these distances as a marker of semantic relatedness was then tested by evaluating whether they could predict the comprehension performance of a patient with global aphasia on two verbal comprehension tasks. It was hypothesized that if the high-dimensional space generated from ACF control ratings approximates the organization of abstract conceptual space, then words separated by small distances should be more semantically related than words separated by greater distances, and should therefore be more difficult to distinguish for the comprehension-impaired patient, SKO. SKO was significantly worse at identifying targets presented within word pairs with low ACF distances. Response accuracy was not predicted by Latent Semantic Analysis (LSA) cosines, any of the individual feature ratings, or any of the background variables. It is argued that this novel rating procedure provides a window on the semantic attributes of individual abstract concepts, and that multiple cognitive systems may influence the acquisition and organization of abstract conceptual knowledge. More broadly, it is suggested that cognitive models of abstract conceptual knowledge must account for the representation not only of the relationships between abstract concepts but also of the attributes which constitute those individual concepts.

  11. Microdrill Initiative - Initial Market Evaluation

    SciTech Connect

    Spears & Associates, Inc

    2003-07-01

    The U.S. Department of Energy (DOE) is launching a major research and development initiative to create a small, fast, inexpensive and environmentally friendly rig for drilling 5000 feet boreholes to investigate potential oil and gas reservoirs. DOE wishes to get input from petroleum industry operators, service companies and equipment suppliers on the operation and application of this coiled-tubing-based drilling unit. To that end, DOE has asked Spears & Associates, Inc. (SAI) to prepare a special state-of-the-market report and assist during a DOE-sponsored project-scoping workshop in Albuquerque near the end of April 2003. The scope of the project is four-fold: (1) Evaluate the history, status and future of demand for very small bore-hole drilling; (2) Measure the market for coiled tubing drilling and describe the state-of-the-art; (3) Identify companies and individuals who should have an interest in micro drilling and invite them to the DOE workshop; and (4) Participate in 3 concurrent workshop sessions, record and evaluate participant comments and report workshop conclusions.

  12. Abstracts of Remediation Case Studies, Volume 9

    EPA Pesticide Factsheets

    This report, published by the Federal Remediation Technologies Roundtable (FRTR), is a collection of recently published abstracts summarizing 13 cost and performance case studies on the use of remediation technologies at contaminated sites.

  13. Paraphrasing for condensation in journal abstracting.

    PubMed

    Kittredge, Richard

    2002-08-01

    When authors of empirical science articles write abstracts, they employ a wide variety of distinct linguistic operations which interact to condense and rephrase a subset of sentences from the source text. An on-going comparison of biological and biomedical journal articles with their author-written abstracts is providing a basis for a more linguistically detailed model of abstract derivation using syntactic representations of selected source sentences. The description makes use of rich dictionary information to formulate paraphrasing rules of differing degrees of generality, including some which are sublanguage-specific, and others which appear valid in several languages when formulated using "lexical functions" to express important semantic relationships between lexical items. Some paraphrase operations may use both lexical functions and rhetorical relations between sentences to reformulate larger chunks of text in a concise abstract sentence. The descriptive framework is computable and utilizes existing linguistic resources.

  14. Program Aims at Improving Abstract Reasoning

    ERIC Educational Resources Information Center

    Chemical and Engineering News, 1977

    1977-01-01

    Describes a program being conducted within the chemistry department of Xavier University, New Orleans, Louisiana, to improve the abstract reasoning abilities of freshmen science majors. The project is based upon the philosophy developed by Jean Piaget. (SL)

  15. Masking failures of multidimensional sensors (extended abstract)

    NASA Technical Reports Server (NTRS)

    Chew, Paul; Marzullo, Keith

    1990-01-01

    When a computer monitors a physical process, the computer uses sensors to determine the values of the physical variables that represent the state of the process. A sensor can sometimes fail, however, and in the worst case report a value completely unrelated to the true physical value. The work described is motivated by a methodology for transforming a process control program that can not tolerate sensor failure into one that can. In this methodology, a reliable abstract sensor is created by combining information from several real sensors that measure the same physical value. To be useful, an abstract sensor must deliver reasonably accurate information at reasonable computational cost. Sensors are considered that deliver multidimensional values (e.g., location or velocity in three dimensions, or both temperature and pressure). Geometric techniques are used to derive upper bounds on abstract sensor accuracy and to develop efficient algorithms for implementing abstract sensors.

  16. Introducing Abstraction to Junior High Students.

    ERIC Educational Resources Information Center

    Costanzo, Nancy

    1981-01-01

    Suggests a way to introduce abstract art to junior high school students who, more than students of any other age, emphasize realism both in their artwork and in their appreciation of works of art. (Author/SJL)

  17. Pulmonary toxicology of respirable particles. [Lead abstract

    SciTech Connect

    Sanders, C.L.; Cross, F.T.; Dagle, G.E.; Mahaffey, J.A.

    1980-09-01

    Separate abstracts were prepared for the 44 papers presented in these proceedings. The last paper (Stannard) in the proceedings is an historical review of the field of inhalation toxicology and is not included in the analytics. (DS)

  18. Writing a research abstract: eloquence in miniature.

    PubMed

    Papanas, N; Georgiadis, G S; Maltezos, E; Lazarides, M K

    2012-06-01

    Abstracts are summaries, usually of a full article or conference presentation, and may be classified into structured and unstructured ones. The former have a predefined layout necessitating the use of headings. Most journals and conferences now use the structured abstract format. Research abstracts are increasingly vital for scientific communication and are expected to continue playing a key role for the dissemination of medicine in the near future. Abstracts take time and need meticulous preparation. They must aptly summarise the content of the study or presentation and avoid vague statements and poor style. Moreover, they must comply with provided instructions. Finally, they should be pleasant to read and encourage study of the corresponding full work.

  19. Hierarchical abstract semantic model for image classification

    NASA Astrophysics Data System (ADS)

    Ye, Zhipeng; Liu, Peng; Zhao, Wei; Tang, Xianglong

    2015-09-01

    Semantic gap limits the performance of bag-of-visual-words. To deal with this problem, a hierarchical abstract semantics method that builds abstract semantic layers, generates semantic visual vocabularies, measures semantic gap, and constructs classifiers using the Adaboost strategy is proposed. First, abstract semantic layers are proposed to narrow the semantic gap between visual features and their interpretation. Then semantic visual words are extracted as features to train semantic classifiers. One popular form of measurement is used to quantify the semantic gap. The Adaboost training strategy is used to combine weak classifiers into strong ones to further improve performance. For a testing image, the category is estimated layer-by-layer. Corresponding abstract hierarchical structures for popular datasets, including Caltech-101 and MSRC, are proposed for evaluation. The experimental results show that the proposed method is capable of narrowing semantic gaps effectively and performs better than other categorization methods.

  20. The semantic richness of abstract concepts

    PubMed Central

    Recchia, Gabriel; Jones, Michael N.

    2012-01-01

    We contrasted the predictive power of three measures of semantic richness—number of features (NFs), contextual dispersion (CD), and a novel measure of number of semantic neighbors (NSN)—for a large set of concrete and abstract concepts on lexical decision and naming tasks. NSN (but not NF) facilitated processing for abstract concepts, while NF (but not NSN) facilitated processing for the most concrete concepts, consistent with claims that linguistic information is more relevant for abstract concepts in early processing. Additionally, converging evidence from two datasets suggests that when NSN and CD are controlled for, the features that most facilitate processing are those associated with a concept's physical characteristics and real-world contexts. These results suggest that rich linguistic contexts (many semantic neighbors) facilitate early activation of abstract concepts, whereas concrete concepts benefit more from rich physical contexts (many associated objects and locations). PMID:23205008

  1. Abstracts of ARI Research Publications, FY 1979

    DTIC Science & Technology

    1980-11-01

    Technical Report 483 ABSTRACTS OF ARI RESEARCH PUBLICATIONS FY 1979 -- C:) U. S . ArmyL.) LAa Research Institute for the Behavioral and Social...U. S . ARMY RESEARCH INSTITUTE FOR THE BEHAVIORAL AND SOCIAL SCIENCES A Field Operating Agency under the Jurisdiction of the Deputy Chief of Staff...PIEIT’S ATALOG NUMBER Technical Report 483 l L~,2 y. (-P- NUZE 4. TITLE (nd Subtfti.) S . TYPE OF REPORT & PERIOD COVERED ABSTRACTS OF ARI RESEARCH

  2. Information Technology Division Technical Paper Abstracts 1995,

    DTIC Science & Technology

    2007-11-02

    Information Technology Division (ITD), one of the largest research and development collectives at the Naval Research Laboratory. The abstracts are organized into sections that represent the six branches with ITD: the Navy Center for Applied Research in Artificial Intelligence, Communications Systems, the Center for High Assurance Computer Systems, Transmission Technology, Advanced Information Technology , and the Center for Computational Science. Within each section, a list of branch papers published in 1993 and 1994 has also been included; abstracts

  3. Earth Sciences Division collected abstracts: 1980

    SciTech Connect

    Henry, A.L.; Hornady, B.F.

    1981-10-15

    This report is a compilation of abstracts of papers, reports, and talks presented during 1980 at national and international meetings by members of the Earth Sciences Division, Lawrence Livermore National Laboratory. The arrangement is alphabetical (by author). For a given report, a bibliographic reference appears under the name of each coauthor, but the abstract itself is given only under the name of the first author (indicated in capital letters) or the first Earth Sciences Division author.

  4. Finding Feasible Abstract Counter-Examples

    NASA Technical Reports Server (NTRS)

    Pasareanu, Corina S.; Dwyer, Matthew B.; Visser, Willem; Clancy, Daniel (Technical Monitor)

    2002-01-01

    A strength of model checking is its ability to automate the detection of subtle system errors and produce traces that exhibit those errors. Given the high computational cost of model checking most researchers advocate the use of aggressive property-preserving abstractions. Unfortunately, the more aggressively a system is abstracted the more infeasible behavior it will have. Thus, while abstraction enables efficient model checking it also threatens the usefulness of model checking as a defect detection tool, since it may be difficult to determine whether a counter-example is feasible and hence worth developer time to analyze. We have explored several strategies for addressing this problem by extending an explicit-state model checker, Java PathFinder (JPF), to search for and analyze counter-examples in the presence of abstractions. We demonstrate that these techniques effectively preserve the defect detection ability of model checking in the presence of aggressive abstraction by applying them to check properties of several abstracted multi-threaded Java programs. These new capabilities are not specific to JPF and can be easily adapted to other model checking frameworks; we describe how this was done for the Bandera toolset.

  5. Merida Initiative: The Answer for Mexico?

    DTIC Science & Technology

    2011-03-15

    Unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT Prior to September 11, 2001, internal strife and drug trafficking increased immensely in Colombia ...Plan Colombia should be the model for Mexico as the Mérida Initiative is still in its infancy. It concludes with recommendations for strengthening the...Mérida Initiative. 15. SUBJECT TERMS Plan Colombia ; Mérida Initiative 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18

  6. Towards an Abstraction-Friendly Programming Model for High Productivity and High Performance Computing

    SciTech Connect

    Liao, C; Quinlan, D; Panas, T

    2009-10-06

    General purpose languages, such as C++, permit the construction of various high level abstractions to hide redundant, low level details and accelerate programming productivity. Example abstractions include functions, data structures, classes, templates and so on. However, the use of abstractions significantly impedes static code analyses and optimizations, including parallelization, applied to the abstractions complex implementations. As a result, there is a common perception that performance is inversely proportional to the level of abstraction. On the other hand, programming large scale, possibly heterogeneous high-performance computing systems is notoriously difficult and programmers are less likely to abandon the help from high level abstractions when solving real-world, complex problems. Therefore, the need for programming models balancing both programming productivity and execution performance has reached a new level of criticality. We are exploring a novel abstraction-friendly programming model in order to support high productivity and high performance computing. We believe that standard or domain-specific semantics associated with high level abstractions can be exploited to aid compiler analyses and optimizations, thus helping achieving high performance without losing high productivity. We encode representative abstractions and their useful semantics into an abstraction specification file. In the meantime, an accessible, source-to-source compiler infrastructure (the ROSE compiler) is used to facilitate recognizing high level abstractions and utilizing their semantics for more optimization opportunities. Our initial work has shown that recognizing abstractions and knowing their semantics within a compiler can dramatically extend the applicability of existing optimizations, including automatic parallelization. Moreover, a new set of optimizations have become possible within an abstraction-friendly and semantics-aware programming model. In the future, we will

  7. Use of focus group interviews with public health nurses to identify the efforts of and challenges faced by branches of the Japan Health Insurance Association to achieve good performance of the Specific Health Guidance initiatives.

    PubMed

    Hayashi, Fumi; Ozawa, Keiko; Kawabata, Teruko; Takemi, Yukari

    2016-01-01

    Objectives Aiming at improvement of the Japan Health Insurance Association's Specific Health Guidance initiatives and human resource development, we conducted a qualitative study to clarify the features necessary for and the challenges hindering the achievement of good performance of the initiatives.Methods From November 2014 to January 2015, we conducted 10 focus group interviews, each 90 minutes long, with 64 public health nurses from 10 Japan Health Insurance Association branches. In addition, self-administered questionnaires were administered to obtain the participants' basic characteristics. After we excluded one group for failing to meet our performance targets, we divided the remaining nine focus groups according to two patterns: Maintenance and Progress. The four focus groups fitting the Maintenance pattern had a well-established track record, and the five focus groups fitting the Progress pattern had a track record of good growth. Using open coding of the interview transcripts, we extracted efforts or needs in two domains, individual and branch, Then, we placed codes in eight main categories: [quality], [general practice], [dietary guidance practice], [success factor], [branch system], [training and skill development], [approach to the member office], and [past efforts]. We further extracted important subcategories based on their rates of appearance within branches.Results Data from 56 female public health nurses working at nine branches were included in the analysis. With respect to the individual domain, subcategories such as "building rapport," "creating the physical environment," and "taking the initiative in evaluating one's own lifestyle" in the 〈high emphasis〉 segment of the [general practice] category were common to both patterns. In addition, "increasing opportunities for training" and "enhancement of training program content" were found for both patterns in relation to the 〈demand〉 segment of the [training and skill development

  8. DSNF AND OTHER WASTE FORM DEGRADATION ABSTRACTION

    SciTech Connect

    J. CUNNANE

    2004-11-19

    Several hundred distinct types of DOE-owned spent nuclear fuel (DSNF) may potentially be disposed in the Yucca Mountain repository. These fuel types represent many more types than can be viably individually examined for their effect on the Total System Performance Assessment for the License Application (TSPA-LA). Additionally, for most of these fuel types, there is no known direct experimental test data for the degradation and dissolution of the waste form in repository groundwaters. The approach used in the TSPA-LA model is, therefore, to assess available information on each of 11 groups of DSNF, and to identify a model that can be used in the TSPA-LA model without differentiating between individual codisposal waste packages containing different DSNF types. The purpose of this report is to examine the available data and information concerning the dissolution kinetics of DSNF matrices for the purpose of abstracting a degradation model suitable for use in describing degradation of the DSNF inventory in the Total System Performance Assessment for the License Application. The data and information and associated degradation models were examined for the following types of DSNF: Group 1--Naval spent nuclear fuel; Group 2--Plutonium/uranium alloy (Fermi 1 SNF); Group 3--Plutonium/uranium carbide (Fast Flux Test Facility-Test Fuel Assembly SNF); Group 4--Mixed oxide and plutonium oxide (Fast Flux Test Facility-Demonstration Fuel Assembly/Fast Flux Test Facility-Test Demonstration Fuel Assembly SNF); Group 5--Thorium/uranium carbide (Fort St. Vrain SNF); Group 6--Thorium/uranium oxide (Shippingport light water breeder reactor SNF); Group 7--Uranium metal (N Reactor SNF); Group 8--Uranium oxide (Three Mile Island-2 core debris); Group 9--Aluminum-based SNF (Foreign Research Reactor SNF); Group 10--Miscellaneous Fuel; and Group 11--Uranium-zirconium hydride (Training Research Isotopes-General Atomics SNF). The analyses contained in this document provide an ''upper-limit'' (i

  9. Automata Learning with Automated Alphabet Abstraction Refinement

    NASA Astrophysics Data System (ADS)

    Howar, Falk; Steffen, Bernhard; Merten, Maik

    on is the key when learning behavioral models of realistic systems, but also the cause of a major problem: the introduction of non-determinism. In this paper, we introduce a method for refining a given abstraction to automatically regain a deterministic behavior on-the-fly during the learning process. Thus the control over abstraction becomes part of the learning process, with the effect that detected non-determinism does not lead to failure, but to a dynamic alphabet abstraction refinement. Like automata learning itself, this method in general is neither sound nor complete, but it also enjoys similar convergence properties even for infinite systems as long as the concrete system itself behaves deterministically, as illustrated along a concrete example.

  10. Fall Meeting abstract submission inspires science poetry

    NASA Astrophysics Data System (ADS)

    Balcerak, Ernie

    2011-08-01

    When the 4 August deadline for submitting Fall Meeting abstracts passed, AGU had received more than 20,000 abstracts, a record-breaking number. The submission process had an unexpected by-product: It inspired some scientists to write haiku on Twitter. (Haiku is a form of Japanese poetry typically having three lines, the first with five syllables, the second with seven, and the third with five.) The following are examples of the haiku tweets, with the hashtag #AGU11AbstractHaiku. (For those who want to keep updated about the Fall Meeting on Twitter, the hashtag is #AGU11.) For more information about the meeting, including registration and housing, visit http://sites.agu.org/fallmeeting/.

  11. Progress in Initiator Modeling

    SciTech Connect

    Hrousis, C A; Christensen, J S

    2009-05-04

    There is great interest in applying magnetohydrodynamic (MHD) simulation techniques to the designs of electrical high explosive (HE) initiators, for the purpose of better understanding a design's sensitivities, optimizing its performance, and/or predicting its useful lifetime. Two MHD-capable LLNL codes, CALE and ALE3D, are being used to simulate the process of ohmic heating, vaporization, and plasma formation in the bridge of an initiator, be it an exploding bridgewire (EBW), exploding bridgefoil (EBF) or slapper type initiator. The initiation of the HE is simulated using Tarver Ignition & Growth reactive flow models. 1-D, 2-D and 3-D models have been constructed and studied. The models provide some intuitive explanation of the initiation process and are useful for evaluating the potential impact of identified aging mechanisms (such as the growth of intermetallic compounds or powder sintering). The end product of this work is a simulation capability for evaluating margin in proposed, modified or aged initiation system designs.

  12. 2011 statistical abstract of the United States

    USGS Publications Warehouse

    Krisanda, Joseph M.

    2011-01-01

    The Statistical Abstract of the United States, published since 1878, is the authoritative and comprehensive summary of statistics on the social, political, and economic organization of the United States.


    Use the Abstract as a convenient volume for statistical reference, and as a guide to sources of more information both in print and on the Web.


    Sources of data include the Census Bureau, Bureau of Labor Statistics, Bureau of Economic Analysis, and many other Federal agencies and private organizations.

  13. Earth Sciences Division collected abstracts: 1979

    SciTech Connect

    Henry, A.L.; Schwartz, L.L.

    1980-04-30

    This report is a compilation of abstracts of papers, internal reports, and talks presented during 1979 at national and international meetings by members of the Earth Sciences Division, Lawrence Livermore Laboratory. The arrangement is alphabetical (by author). For a given report, a bibliographic reference appears under the name of each coauthor, but the abstract iself is given only under the name of the first author or the first Earth Sciences Division author. A topical index at the end of the report provides useful cross references, while indicating major areas of research interest in the Earth Sciences Division.

  14. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 13)

    NASA Technical Reports Server (NTRS)

    1978-01-01

    This bibliography is issued in two sections: Section 1 - Abstracts, and Section 2 - Indexes. This issue of the Abstract Section cites 161 patents and applications for patent introduced into the NASA scientific and technical information system during the period January 1978 through June 1978. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or application for patent.

  15. Ports Initiative

    EPA Pesticide Factsheets

    The purpose of the ports initiative is to assist EPA and other participants to formulate strategies for moving forward on actions addressing the transportation, air quality and climate issues raised in the National Conversations.

  16. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 09)

    NASA Technical Reports Server (NTRS)

    1976-01-01

    This bibliography is issued in two sections: Section 1 - Abstracts, and Section 2 - Indexes. This issue of the Abstract Section cites 200 patents and applications for patent introduced into the NASA scientific and technical information system during the period of January 1976 through June 1976. Each entry in the Abstract Section consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or application for patent. This issue of the Index Section contains entries for 2994 patent and application for patent citations covering the period May 1969 through June 1976. The Index Section contains five indexes -- subject, inventor, source, number and accession number.

  17. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 07)

    NASA Technical Reports Server (NTRS)

    1975-01-01

    This bibliography is issued in two sections: Section 1 - Abstracts, and Section 2 - Indexes. This issue of the Abstract Section cites 158 patents and applications for patent introduced into the NASA scientific and technical information system during the period of January 1975 through June 1975. Each entry in the Abstract Section consists of a citation, an abstract, and, in most cases, a key illustration selected from the patent or application for patent. This issue of the Index Section contains entries for 2830 patent and application for patent citations covering the period May 1969 through June 1975. The index section contains five indexes -- subject, inventor, source, number and accession number.

  18. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 08)

    NASA Technical Reports Server (NTRS)

    1976-01-01

    This bibliography is issued in two sections; abstracts and indexes. The Abstract Section cites 180 patents and applications for patents introduced into the NASA scientific and technical information system during the period of July 1975 through December 1975. Each entry in the Abstract Section consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or application for patent. The index Section contains entries for 2,905 patents and applications for patent citations covering the period May 1969 through December 1975. The Index Section contains five indexes -- subject, inventor, source, number and accession number.

  19. Modelling the influence of irrigation abstractions on Scotland's water resources.

    PubMed

    Dunn, S M; Chalmers, N; Stalham, M; Lilly, A; Crabtree, B; Johnston, L

    2003-01-01

    Legislation to control abstraction of water in Scotland is limited and for purposes such as irrigation there are no restrictions in place over most of the country. This situation is set to change with implementation of the European Water Framework Directive. As a first step towards the development of appropriate policy for irrigation control there is a need to assess the current scale of irrigation practices in Scotland. This paper presents a modelling approach that has been used to quantify spatially the volume of water abstractions across the country for irrigation of potato crops under typical climatic conditions. A water balance model was developed to calculate soil moisture deficits and identify the potential need for irrigation. The results were then combined with spatial data on potato cropping and integrated to the sub-catchment scale to identify the river systems most at risk from over-abstraction. The results highlight that the areas that have greatest need for irrigation of potatoes are all concentrated in the central east-coast area of Scotland. The difference between irrigation demand in wet and dry years is very significant, although spatial patterns of the distribution are similar.

  20. Mathematical Abstraction in the Solving of Ill-Structured Problems by Elementary School Students in Korea

    ERIC Educational Resources Information Center

    Hong, Jee Yun; Kim, Min Kyeong

    2016-01-01

    Ill-structured problems can be regarded as one of the measures that meet recent social needs emphasizing students' abilities to solve real-life problems. This study aimed to analyze the mathematical abstraction process in solving such problems, and to identify the mathematical abstraction level ([I] Recognition of mathematical structure through…

  1. Hydrogeological conditions of a crystalline aquifer: simulation of optimal abstraction rates under scenarios of reduced recharge.

    PubMed

    Yidana, Sandow Mark; Fynn, Obed Fiifi; Chegbeleh, Larry Pax; Nude, Prosper M; Asiedu, Daniel K

    2013-01-01

    A steady state numerical groundwater flow model has been calibrated to characterize the spatial distribution of a key hydraulic parameter in a crystalline aquifer in southwestern Ghana. This was to provide an initial basis for characterizing the hydrogeology of the terrain with a view to assisting in the large scale development of groundwater resources for various uses. The results suggest that the structural entities that control groundwater occurrence in the area are quite heterogeneous in their nature and orientation, ascribing hydraulic conductivity values in the range of 4.5 m/d to over 70 m/d to the simulated aquifer. Aquifer heterogeneities, coupled possibly with topographical trends, have led to the development of five prominent groundwater flowpaths in the area. Estimated groundwater recharge at calibration ranges between 0.25% and 9.13% of the total annual rainfall and appears to hold significant promise for large-scale groundwater development to support irrigation schemes. However, the model suggests that with reduced recharge by up to 30% of the current rates, the system can only sustain increased groundwater abstraction by up to 150% of the current abstraction rates. Prudent management of the resource will require a much more detailed hydrogeological study that identifies all the aquifers in the basin for the assessment of sustainable basin yield.

  2. Hydrogeological Conditions of a Crystalline Aquifer: Simulation of Optimal Abstraction Rates under Scenarios of Reduced Recharge

    PubMed Central

    Fynn, Obed Fiifi; Chegbeleh, Larry Pax; Nude, Prosper M.; Asiedu, Daniel K.

    2013-01-01

    A steady state numerical groundwater flow model has been calibrated to characterize the spatial distribution of a key hydraulic parameter in a crystalline aquifer in southwestern Ghana. This was to provide an initial basis for characterizing the hydrogeology of the terrain with a view to assisting in the large scale development of groundwater resources for various uses. The results suggest that the structural entities that control groundwater occurrence in the area are quite heterogeneous in their nature and orientation, ascribing hydraulic conductivity values in the range of 4.5 m/d to over 70 m/d to the simulated aquifer. Aquifer heterogeneities, coupled possibly with topographical trends, have led to the development of five prominent groundwater flowpaths in the area. Estimated groundwater recharge at calibration ranges between 0.25% and 9.13% of the total annual rainfall and appears to hold significant promise for large-scale groundwater development to support irrigation schemes. However, the model suggests that with reduced recharge by up to 30% of the current rates, the system can only sustain increased groundwater abstraction by up to 150% of the current abstraction rates. Prudent management of the resource will require a much more detailed hydrogeological study that identifies all the aquifers in the basin for the assessment of sustainable basin yield. PMID:24453882

  3. Hubble Exoplanet Pro/Am Collaboration (Abstract)

    NASA Astrophysics Data System (ADS)

    Conti, D. M.

    2016-06-01

    (Abstract only) A collaborative effort is being organized between a world-wide network of amateur astronomers and a Hubble Space Telescope (HST) science team. The purpose of this collaboration is to supplement an HST near-infrared spectroscopy survey of some 15 exoplanets with ground-based observations in the visible range.

  4. A Photographic Assignment for Abstract Algebra

    ERIC Educational Resources Information Center

    Warrington, Gregory S.

    2009-01-01

    We describe a simple photographic assignment appropriate for an abstract algebra (or other) course. Students take digital pictures around campus of various examples of symmetry. They then classify these pictures according to which of the 17 plane symmetry groups they belong. (Contains 2 figures.)

  5. Does Abstracting Threaten a Sustainable Future?

    ERIC Educational Resources Information Center

    Grant, Lyle K.

    2012-01-01

    In abstraction, or conceptual behavior, people discriminate features or properties of their surroundings. This permits people to respond selectively and precisely to specialized features of their environment, which has had many benefits, including steady advances in science and technology. Within psychology, J. R. Kantor and B. F. Skinner…

  6. Using Group Explorer in Teaching Abstract Algebra

    ERIC Educational Resources Information Center

    Schubert, Claus; Gfeller, Mary; Donohue, Christopher

    2013-01-01

    This study explores the use of Group Explorer in an undergraduate mathematics course in abstract algebra. The visual nature of Group Explorer in representing concepts in group theory is an attractive incentive to use this software in the classroom. However, little is known about students' perceptions on this technology in learning concepts in…

  7. Abstracts of Research, July 1975-June 1976.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Computer and Information Science Research Center.

    Abstracts of research papers in computer and information science are given for 62 papers in the areas of information storage and retrieval; computer facilities; information analysis; linguistics analysis; artificial intelligence; information processes in physical, biological, and social systems; mathematical technigues; systems programming;…

  8. Abstracts of Research. July 1974-June 1975.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Computer and Information Science Research Center.

    Abstracts of research papers in computer and information science are given for 68 papers in the areas of information storage and retrieval; human information processing; information analysis; linguistic analysis; artificial intelligence; information processes in physical, biological, and social systems; mathematical techniques; systems…

  9. Three New Z Cam Stars (Abstract)

    NASA Astrophysics Data System (ADS)

    Simonsen, M.

    2016-12-01

    (Abstract only) I will present the evidence and discovery stories of three cataclysmic variables who appear to be members of the Z Cam class of dwarf novae. One discovered by a lone visual observer and his unwavering patience and persistence, one through the directed effort of the ongoing Z CamPaign and one via survey data from the Gaia satellite.

  10. Natural radiation environment III. [Lead Abstract

    SciTech Connect

    Gesell, T.F.; Lowder, W.M.

    1980-01-01

    Separate abstracts were prepared for the 52 research papers presented at this symposium in April 1978. The major topics in this volume deal with penetrating radiation measurements, radiation surveys and population exposure, radioactivity in the indoor environment, and technologically enhanced natural radioactivity. (KRM)

  11. C. M. Louttit and "Psychological Abstracts"

    ERIC Educational Resources Information Center

    Littman, Richard A.

    2007-01-01

    R. A. Littman indicates that L. T. Benjamin and G. R. VandenBos's history of Psychological Abstracts is a fine account of how the American Psychological Association has carried out its responsibility to provide access to psychological research and writing. Littman was pleased to see Mac Louttit's work as editor brought out, and he takes this…

  12. Development of Abstract Grammatical Categorization in Infants

    ERIC Educational Resources Information Center

    Cyr, Marilyn; Shi, Rushen

    2013-01-01

    This study examined abstract syntactic categorization in infants, using the case of grammatical gender. Ninety-six French-learning 14-, 17-, 20-, and 30-month-olds completed the study. In a preferential looking procedure infants were tested on their generalized knowledge of grammatical gender involving pseudonouns and gender-marking determiners.…

  13. Carbon Monoxide, A Bibliography With Abstracts.

    ERIC Educational Resources Information Center

    Cooper, Anna Grossman

    Included is a review of the carbon monoxide related literature published from 1880 to 1966. The 983 references with abstracts are grouped into these broad categories: Analysis, Biological Effects, Blood Chemistry, Control, Criteria and Standards, Instruments and Techniques, Sampling and Network Operations, and Sources. The Biological Effects group…

  14. Harmonious Triptychs: From Realism to Abstraction

    ERIC Educational Resources Information Center

    Horst, Carol

    2006-01-01

    The author of this article is continually trying to come up with interesting ways for beginning art students to put color theory into practice. This article describes a project that integrates new learning about color schemes with previously learned concepts such as observational contour drawing and abstraction and converting two-dimensional shape…

  15. An Introduction to Chemical Abstracts, with Exercises.

    ERIC Educational Resources Information Center

    Robertson, Craig A.

    This workbook is the first in a series of three that has been integrated into the chemistry curriculum for majors at the University of Vermont. The workbook consists of exercises designed to provide undergraduate students with foundation skills in the use of professional literature and a familiarity with the printed "Chemical Abstracts."…

  16. Cool Cats: Feline Fun with Abstract Art.

    ERIC Educational Resources Information Center

    Lambert, Phyllis Gilchrist

    2002-01-01

    Presents a lesson that teaches students about abstract art in a fun way. Explains that students draw cats, learn about the work of Pablo Picasso, and, in the style of Picasso, combine the parts of the cats (tail, legs, head, body) together in unconventional ways. (CMK)

  17. RCDPM 1992 Conference Book of Abstracts.

    ERIC Educational Resources Information Center

    1992

    This booklet contains 51 abstracts of papers presented at the 1992 conference for the Research Council for Diagnostic and Prescriptive Mathematics (RCDPM). Topics covered include: the use of expressive writing to enhance metacognition, adult assessment, cooperative learning assessment, visualization in problem solving, deaf students' beliefs about…

  18. Abstract Journals: A Survey of Patent Coverage.

    ERIC Educational Resources Information Center

    Rimmer, Brenda M.

    1988-01-01

    Describes a survey of 33 British, French, German, and U.S. abstract journals that examined their coverage of patent specifications. The standards for the identification of patent documents developed by the World Intellectual Property Organization are discussed, and an appendix provides a listing of the patent coverage by the country of each…

  19. Heat pipe technology. A bibliography with abstracts

    NASA Technical Reports Server (NTRS)

    1978-01-01

    This bibliography cites 55 publications on the theory, design, development, fabrication, and testing of heat pipes. Applications covered include solar, nuclear, and thermoelectric energy conversion. A book (in Russian) on low temperature heat pipes is included as well as abstracts when available. Indexes provided list authors, titles/keywords (permuted) and patents.

  20. Abstracts of Energy Materials for College Classes.

    ERIC Educational Resources Information Center

    Messenger, Roger A.; And Others

    This guide provides citations and abstracts for 250 energy-related resources which can be used to incorporate energy education into the structure of existing college courses. In addition to citing books, articles, unpublished papers, films, and videotapes, the resource guide cites sets of class notes and course outlines that have been filed with…

  1. Adopting Abstract Images for Semantic Scene Understanding.

    PubMed

    Zitnick, C Lawrence; Vedantam, Ramakrishna; Parikh, Devi

    2016-04-01

    Relating visual information to its linguistic semantic meaning remains an open and challenging area of research. The semantic meaning of images depends on the presence of objects, their attributes and their relations to other objects. But precisely characterizing this dependence requires extracting complex visual information from an image, which is in general a difficult and yet unsolved problem. In this paper, we propose studying semantic information in abstract images created from collections of clip art. Abstract images provide several advantages over real images. They allow for the direct study of how to infer high-level semantic information, since they remove the reliance on noisy low-level object, attribute and relation detectors, or the tedious hand-labeling of real images. Importantly, abstract images also allow the ability to generate sets of semantically similar scenes. Finding analogous sets of real images that are semantically similar would be nearly impossible. We create 1,002 sets of 10 semantically similar abstract images with corresponding written descriptions. We thoroughly analyze this dataset to discover semantically important features, the relations of words to visual features and methods for measuring semantic similarity. Finally, we study the relation between the saliency and memorability of objects and their semantic importance.

  2. Simulation, Design Abstraction, and SystemC

    ERIC Educational Resources Information Center

    Harcourt, Ed

    2007-01-01

    SystemC is a system-level design and simulation language based on C++. We've been using SystemC for computer organization and design projects for the past several years. Because SystemC is embedded in C++ it contains the powerful abstraction mechanisms of C++ not found in traditional hardware description languages, such as support for…

  3. Heat pipe technology: A bibliography with abstracts

    NASA Technical Reports Server (NTRS)

    1971-01-01

    The annual supplement on heat pipe technology for 1971 is presented. The document contains 101 references with abstracts and 47 patents. The subjects discussed are: (1) heat pipe applications, (2) heat pipe theory, (3) design, development, and fabrication of heat pipes, (4) testing and operation, (5) subject and author index, and (6) heat pipe related patents.

  4. Reducing Abstraction When Learning Graph Theory

    ERIC Educational Resources Information Center

    Hazzan, Orit; Hadar, Irit

    2005-01-01

    This article presents research on students' understanding of basic concepts in Graph Theory. Students' understanding is analyzed through the lens of the theoretical framework of reducing abstraction (Hazzan, 1999). As it turns out, in spite of the relative simplicity of the concepts that are introduced in the introductory part of a traditional…

  5. Contextualising Numeracy: Abstract Tools at the Coalface.

    ERIC Educational Resources Information Center

    Lukin, Annabelle

    1998-01-01

    A social semiotic approach to math is necessary because of the increasing significance of abstract tools in the workplace. A case study from the coal mining industry illustrates the need to recognize mathematics as a socially constructed system and to contextualize math instruction. (SK)

  6. The Learnability of Abstract Syntactic Principles

    ERIC Educational Resources Information Center

    Perfors, Amy; Tenenbaum, Joshua B.; Regier, Terry

    2011-01-01

    Children acquiring language infer the correct form of syntactic constructions for which they appear to have little or no direct evidence, avoiding simple but incorrect generalizations that would be consistent with the data they receive. These generalizations must be guided by some inductive bias--some abstract knowledge--that leads them to prefer…

  7. Abstracts of Research Papers 1977 AAHPER Convention.

    ERIC Educational Resources Information Center

    Sage, George H., Ed.

    This volume of abstracts describes papers written on the following topics: (1) Strength Physiology; (2) Learning Disabilities (motor); (3) Physiology - General; (4) Work Capacity; (5) Measurement and Recreation; (6) Biomechanics; (7) Professional Preparation (physical education); (8) Muscle Performance; (9) Sociology of Sport; (10) History of…

  8. Spatial abstraction for autonomous robot navigation.

    PubMed

    Epstein, Susan L; Aroor, Anoop; Evanusa, Matthew; Sklar, Elizabeth I; Parsons, Simon

    2015-09-01

    Optimal navigation for a simulated robot relies on a detailed map and explicit path planning, an approach problematic for real-world robots that are subject to noise and error. This paper reports on autonomous robots that rely on local spatial perception, learning, and commonsense rationales instead. Despite realistic actuator error, learned spatial abstractions form a model that supports effective travel.

  9. Hilson Adolescent Profile (HAP): Hilson Research Abstracts.

    ERIC Educational Resources Information Center

    Hilson Research Inc., Kew Gardens, NY.

    Abstracts and bibliographic citations are given for the following documents concerned with the use and characteristics of the Hilson Adolescent Profile (HAP): (1) "Use of the Hilson Adolescent Profile To Compare Juvenile Offenders with Junior and Senior High School Students" (R. E. Inwald and K. E. Brobst); (2) "The Effectiveness of…

  10. The Paradox of Abstraction: Precision Versus Concreteness.

    PubMed

    Iliev, Rumen; Axelrod, Robert

    2016-11-22

    We introduce a novel measure of abstractness based on the amount of information of a concept computed from its position in a semantic taxonomy. We refer to this measure as precision. We propose two alternative ways to measure precision, one based on the path length from a concept to the root of the taxonomic tree, and another one based on the number of direct and indirect descendants. Since more information implies greater processing load, we hypothesize that nouns higher in precision will have a processing disadvantage in a lexical decision task. We contrast precision to concreteness, a common measure of abstractness based on the proportion of sensory-based information associated with a concept. Since concreteness facilitates cognitive processing, we predict that while both concreteness and precision are measures of abstractness, they will have opposite effects on performance. In two studies we found empirical support for our hypothesis. Precision and concreteness had opposite effects on latency and accuracy in a lexical decision task, and these opposite effects were observable while controlling for word length, word frequency, affective content and semantic diversity. Our results support the view that concepts organization includes amodal semantic structures which are independent of sensory information. They also suggest that we should distinguish between sensory-based and amount-of-information-based abstractness.

  11. Abstracts, Third Space Processing Symposium, Skylab results

    NASA Technical Reports Server (NTRS)

    1974-01-01

    Skylab experiments results are reported in abstracts of papers presented at the Third Space Processing Symposium. Specific areas of interest include: exothermic brazing, metals melting, crystals, reinforced composites, glasses, eutectics; physics of the low-g processes; electrophoresis, heat flow, and convection demonstrations flown on Apollo missions; and apparatus for containerless processing, heating, cooling, and containing materials.

  12. The Child and the Abstract Expressionist.

    ERIC Educational Resources Information Center

    Henkes, Robert

    1990-01-01

    Explores the similarities between paintings of the abstract expressionists and those of young children. Similarities include total surface coverage, disregard for details, direct application of pigment, disregard for visual perspective, and use of the painting surface as a frontal plane. (CB)

  13. Organizational Communication 1976: Abstracts, Analysis, and Overview.

    ERIC Educational Resources Information Center

    Falcione, Raymond L.; Greenbaum, Howard H.

    A contribution to the literature on organizational communication, this book has three objectives: to provide access to information on recent literature in organizational communication; to develop a classification system for the literature; and to provide abstracts of the literature published in 1976. The introductory chapter comments on the year's…

  14. Searching Chemical Abstracts Online in Undergraduate Chemistry.

    ERIC Educational Resources Information Center

    Krumpolc, Miroslav; And Others

    1987-01-01

    Discusses the advantages of conducting online computer searches of "Chemical Abstracts." Introduces the logical sequences involved in searching an online database. Explains Boolean logic, proximity operators, truncation, searchable fields, and command language, as they relate to the use of online searches in undergraduate chemistry…

  15. NASA SBIR abstracts of 1990 phase 1 projects

    NASA Technical Reports Server (NTRS)

    Schwenk, F. C.; Gilman, J. A.; Paige, J. B.

    1991-01-01

    The research objectives of the 280 projects placed under contract in the National Aeronautics and Space Administration (NASA) 1990 Small Business Innovation Research (SBIR) Phase 1 program are described. The basic document consists of edited, non-proprietary abstracts of the winning proposals submitted by small businesses in response to NASA's 1990 SBIR Phase 1 Program Solicitation. The abstracts are presented under the 15 technical topics within which Phase 1 proposals were solicited. Each project was assigned a sequential identifying number from 001 to 280, in order of its appearance in the body of the report. The document also includes Appendixes to provide additional information about the SBIR program and permit cross-reference in the 1990 Phase 1 projects by company name, location by state, principal investigator, NASA field center responsible for management of each project, and NASA contract number.

  16. NASA SBIR abstracts of 1992, phase 1 projects

    NASA Technical Reports Server (NTRS)

    Schwenk, F. C.; Gilman, J. A.; Paige, J. B.; Sacknoff, S. M.

    1993-01-01

    The objectives of 346 projects placed under contract by the Small Business Innovation Research (SBIR) program of the National Aeronautics and Space Administration (NASA) are described. These projects were selected competitively from among proposals submitted to NASA in response to the 1992 SBIR Program Solicitation. The basic document consists of edited, non-proprietary abstracts of the winning proposals submitted by small businesses. The abstracts are presented under the 15 technical topics within which Phase 1 proposals were solicited. Each project was assigned a sequential identifying number from 001 to 346, in order of its appearance in the body of the report. Appendixes to provide additional information about the SBIR program and permit cross-reference of the 1992 Phase 1 projects by company name, location by state, principal investigator, NASA Field Center responsible for management of each project, and NASA contract number are included.

  17. NASA SBIR abstracts of 1991 phase 1 projects

    NASA Technical Reports Server (NTRS)

    Schwenk, F. Carl; Gilman, J. A.; Paige, J. B.

    1992-01-01

    The objectives of 301 projects placed under contract by the Small Business Innovation Research (SBIR) program of the National Aeronautics and Space Administration (NASA) are described. These projects were selected competitively from among proposals submitted to NASA in response to the 1991 SBIR Program Solicitation. The basic document consists of edited, non-proprietary abstracts of the winning proposals submitted by small businesses. The abstracts are presented under the 15 technical topics within which Phase 1 proposals were solicited. Each project was assigned a sequential identifying number from 001 to 301, in order of its appearance in the body of the report. Appendixes to provide additional information about the SBIR program and permit cross-reference of the 1991 Phase 1 projects by company name, location by state, principal investigator, NASA Field Center responsible for management of each project, and NASA contract number are included.

  18. Hanford tanks initiative plan

    SciTech Connect

    McKinney, K.E.

    1997-07-01

    Abstract: The Hanford Tanks Initiative (HTI) is a five-year project resulting from the technical and financial partnership of the U.S. Department of Energy`s Office of Waste Management (EM-30) and Office of Science and Technology Development (EM-50). The HTI project accelerates activities to gain key technical, cost performance, and regulatory information on two high-level waste tanks. The HTI will provide a basis for design and regulatory decisions affecting the remainder of the Tank Waste Remediation System`s tank waste retrieval Program.

  19. Abstract Mindsets Increase Believability of Spatially Distant Online Messages

    PubMed Central

    Sungur, Hande; Hartmann, Tilo; van Koningsbruggen, Guido M.

    2016-01-01

    Growing evidence from online credibility research reveals that online users rely on heuristic processes to evaluate the credibility of online information. The current paper, which is based on the construal level theory (CLT), proposes that congruency between the psychological distance of a stimulus and the way it is mentally construed can act as a heuristic for believability. According to CLT, psychologically close (e.g., spatially, temporally, socially) stimuli are represented concretely whereas psychologically distant stimuli are represented abstractly. The level of mental construals and the psychological distance of information have been shown to influence people’s truth judgments in offline contexts. This study tests whether congruency between the construal level of people’s mindsets (abstract vs. concrete) and the psychological distance implied in an online message (far vs. close) enhances message believability. By partially confirming CLT predictions, we found that believability of an online news item about a distant location increased when people maintained an abstract mindset rather than a concrete one. The effect of a concrete mindset on believability was not significant for the close psychological distance condition. Our findings provide initial evidence that congruency between the construal level of people’s mindsets and psychological distance cues in online messages can act as a heuristic for believability. We discuss the potential of applying the CLT framework to the growing literature on online cognitive heuristics in the area of online information credibility. PMID:27468272

  20. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 17)

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Abstracts are cited for 150 patents and applications for patents introduced into the NASA scientific and technical information system during the period January 1980 through June 1980. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or application for patent.

  1. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 42)

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Abstracts are provided for 174 patents and patent applications entered into the NASA scientific and technical information system during the period July 1992 through December 1992. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  2. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 30)

    NASA Technical Reports Server (NTRS)

    1987-01-01

    Abstracts are provided for 105 patents and patent applications entered into the NASA scientific and technical information system during the period July 1986 through December 1986. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  3. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 39)

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Abstracts are provided for 154 patents and patent applications entered into the NASA scientific and technical information systems during the period Jan. 1991 through Jun. 1991. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  4. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 32)

    NASA Technical Reports Server (NTRS)

    1988-01-01

    Abstracts are provided for 136 patents and patent applications entered into the NASA scientific and technical information system during the period July through December 1987. Each entry consists of a citation , an abstract, and in most cases, a key illustration selected from the patent or patent application.

  5. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 36)

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Abstracts are provided for 63 patents and patent applications entered into the NASA scientific and technical information systems during the period July 1989 through December 1989. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  6. Choosing a Database for Social Work: A Comparison of Social Work Abstracts and Social Service Abstracts

    ERIC Educational Resources Information Center

    Flatley, Robert K.; Lilla, Rick; Widner, Jack

    2007-01-01

    This study compared Social Work Abstracts and Social Services Abstracts databases in terms of indexing, journal coverage, and searches. The authors interviewed editors, analyzed journal coverage, and compared searches. It was determined that the databases complement one another more than compete. The authors conclude with some considerations.

  7. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 14)

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Abstracts are cited for 213 patents and applications for patent introduced into the NASA scientific and technical information system during the period of July 1978 through December 1978. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or application for patent.

  8. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 26)

    NASA Technical Reports Server (NTRS)

    1985-01-01

    Abstracts are provided for 172 patents and patent applications entered into the NASA scientific and technical information system during the period July 1984 through December 1984. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  9. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 16)

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Abstracts are cited for 138 patents and patent applications introduced into the NASA scientific and technical information system during the period July 1979 through December 1979. Each entry cib consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  10. NASA patent abstracts bibliography. A continuing bibliography (supplement 22). Section 1: Abstracts

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Abstracts are cited for 234 patents and patent applications introduced into the NASA scientific and technical information system during the period July 1982 through December 1982. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  11. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 35)

    NASA Technical Reports Server (NTRS)

    1989-01-01

    Abstracts are provided for 58 patents and patent applications entered into the NASA scientific and technical information systems during the period January 1989 through June 1989. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  12. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 25)

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Abstracts are provided for 102 patents and patent applications entered into the NASA scientific and technical information system during the period January 1984 through June 1984. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  13. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 45)

    NASA Technical Reports Server (NTRS)

    1994-01-01

    Abstracts are provided for 137 patents and patent applications entered into the NASA scientific and technical information system during the period Jan. 1994 through Jun. 1994. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  14. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 33)

    NASA Technical Reports Server (NTRS)

    1988-01-01

    Abstracts are provided for 16 patents and patent applications entered into the NASA scientific and technical information systems during the period January 1988 through June 1988. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  15. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 24)

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Abstracts are provided for 167 patents and patent applications entered into the NASA scientific and technical information system during the period July 1983 through December 1983. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  16. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 31)

    NASA Technical Reports Server (NTRS)

    1987-01-01

    Abstracts are provided for 85 patents and patent applications entered into the NASA scientific and technical information system during the period January 1987 through June 1987. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  17. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 15)

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Abstracts are cited for 240 patents and applications for patents introduced into the NASA scientific system during the period of January 1979 through June 1979. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or application for patent.

  18. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 40)

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Abstracts are provided for 181 patents and patent applications entered into the NASA scientific and technical information system during the period July 1991 through December 1991. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  19. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 44)

    NASA Technical Reports Server (NTRS)

    1994-01-01

    Abstracts are provided for 131 patents and patent applications entered into the NASA scientific and technical information system during the period Jun. 1993 through Dec. 1993. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  20. NASA Patent Abstracts Bibliography: A Continuing Bibliography. Section 1: Abstracts (Supplement 48)

    NASA Technical Reports Server (NTRS)

    1996-01-01

    Abstracts are provided for 85 patents and patent applications entered into the NASA scientific and technical information system during the period July 1995 through December 1995. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  1. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 29)

    NASA Technical Reports Server (NTRS)

    1986-01-01

    Abstracts are provided for 115 patents and patent applications entered into the NASA scientific and technical information system during the period January 1986 through June 1986. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent application.

  2. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 41)

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Abstracts are provided for 131 patents and patent applications entered into the NASA scientific and technical information system during the period Jan. 1992 through Jun. 1992. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  3. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 38)

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Abstracts are provided for 132 patents and patent applications entered into the NASA scientific and technical information system during the period July 1990 through December 1990. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  4. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 18)

    NASA Technical Reports Server (NTRS)

    1981-01-01

    Abstracts are cited for 120 patents and patent applications for patents introduced into the NASA scientific system during the period of July 1980 through December 1980. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or application for patent.

  5. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 34)

    NASA Technical Reports Server (NTRS)

    1989-01-01

    Abstracts are provided for 124 patents and patent applications entered into the NASA scientific and technical information systems during the period July 1988 through December 1988. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  6. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 19)

    NASA Technical Reports Server (NTRS)

    1981-01-01

    Abstracts are cited for 130 patents and patent applications introduced into the NASA scientific and technical information system during the period of January 1981 through July 1981. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or application for patent.

  7. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 28)

    NASA Technical Reports Server (NTRS)

    1986-01-01

    Abstracts are provided for 109 patents and patent applications entered into the NASA Scientific and Technical Information System during the period July 1985 through December 1985. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  8. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 27)

    NASA Technical Reports Server (NTRS)

    1985-01-01

    Abstracts are provided for 92 patents and patent applications entered into the NASA scientific and technical information system during the period January 1985 through June 1985. Each entry consist of a citation, and abstract, and in most cases, a key illustration selected from the patent or patent application.

  9. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 23)

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Abstracts are cited for 129 patents and patent applications introduced into the NASA scientific and technical information system during the period January 1983 through June 1983. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  10. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 20)

    NASA Technical Reports Server (NTRS)

    1982-01-01

    Abstracts are cited for 165 patents and patent applications introduced into the NASA scientific and technical information system during the period July 1981 through December 1981. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  11. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 43)

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Abstracts are provided for 128 patents and patent applications entered into the NASA scientific and technical information system during the period Jan. 1993 through Jun. 1993. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  12. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 37)

    NASA Technical Reports Server (NTRS)

    1989-01-01

    Abstracts are provided for 76 patents and patent applications entered into the NASA scientific and technical information systems during the period January 1990 through June 1990. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or patent application.

  13. Hydrogen Abstraction from Hydrocarbons by NH2.

    PubMed

    Siddique, Kamal; Altarawneh, Mohammednoor; Gore, Jeff; Westmoreland, Phillip R; Dlugogorski, Bogdan Z

    2017-03-23

    This contribution investigates thermokinetic parameters of bimolecular gas-phase reactions involving the amine (NH2) radical and a large number of saturated and unsaturated hydrocarbons. These reactions play an important role in combustion and pyrolysis of nitrogen-rich fuels, most notably biomass. Computations performed at the CBS-QB3 level and based on the conventional transition-state theory yield potential-energy surfaces and reaction rate constants, accounting for tunnelling effects and the presence of hindered rotors. In an analogy to other H abstraction systems, we demonstrate only a small influence of variational effects on the rate constants for selected reaction. The studied reactions cover the abstraction of hydrogen atoms by the NH2 radical from the C-H bonds in C1-C4 species, and four C5 hydrocarbons of 2-methylbutane, 2-methyl-1-butene, 3-methyl-1-butene, 3-methyl-2-butene, and 3-methyl-1-butyne. For the abstraction of H from methane, in the temperature windows 300-500 and 1600-2000 K, the calculated reaction rate constants concur with the available experimental measurements, i.e., kcalculated/kexperimetal = 0.3-2.5 and 1.1-1.4, and the previous theoretical estimates. Abstraction of H atom from ethane attains the ratio of kcalculated/kexperimetal equal to 0.10-1.2 and 1.3-1.5 over the temperature windows of available experimental measurements, i.e., 300-900 K and 1500-2000 K, respectively. For the remaining alkanes (propane and n-butane), the average kexperimental/kcalculated ratio remains 2.6 and 1.3 over the temperature range of experimental data. Also, comparing the calculated standard enthalpy of reaction (ΔrH°298) with the available experimental measurements for alkanes, we found the mean unsigned error of computations as 3.7 kJ mol(-1). This agreement provides an accuracy benchmark of our methodology, affording the estimation of the unreported kinetic parameters for H abstractions from alkenes and alkynes. On the basis of the Evans

  14. Abstracts from the 2016 Annual Louisiana American College of Physicians Associates Meeting.

    PubMed

    Engel, Lee S; Davis, William

    2016-01-01

    Each year medical students in Louisiana and residents from the eight Internal Medicine training programs in Louisiana are invited to submit abstracts for the Annual Louisiana American College of Physicians (ACP) Associates Meeting. The content of these abstracts includes clinical case vignettes or research activities. The abstracts have all identifying features removed (i.e., names, institutional affiliations, etc.) before being sent to physician judges. Each judge scores each abstract independently and then the scores from all judges are averaged and ranked. This year we are excited to be able to publish most highly ranked abstracts presented at this year's competition. These abstracts (17 oral; 14 poster) were presented at the Associates Meeting held at LSU Health Sciences Center in Baton Rouge on January 19, 2016. We would like to thank the Journal of the Louisiana State Medical Society and appreciate its efforts to publicize the hard work of these trainees.

  15. Space Electrochemical Research and Technology. Abstracts

    NASA Technical Reports Server (NTRS)

    1995-01-01

    This document contains abstracts of the proceedings of NASA's fifth Space Electrochemical Research and Technology (SERT) Conference, held at the NASA Lewis Research Center on May 1-3, 1995. The objective of the conference was to assess the present status and general thrust of research and development in those areas of electrochemical technology required to enable NASA missions into the next century. The conference provided a forum for the exchange of ideas and opinions of those actively involved in the field, in order to define new opportunities for the application of electrochemical processes in future NASA missions. Papers were presented in three technical areas: (1) the electrochemical interface, (2) the next generation in aerospace batteries and fuel cells, and (3) electrochemistry for non-energy storage applications. This document contains the abstracts of the papers presented.

  16. FFCAct Clearinghouse, Directory of abstracts. Revision 1

    SciTech Connect

    Harwood, T.

    1994-05-01

    The Federal Facility Compliance Act (FFCAct) Clearinghouse is a card catalog of information about the FFCAct and its requirements for developing Site Treatment Plans (STP). The information available in the clearinghouse includes abstracts describing computer applications, technical reports, and a list of technical experts. Information can be accessed for use in responding to FFCAct requirements, and the clearinghouse provides search capabilities on particular topics and issues related to STP development. Appendix A includes: contacts from each site, for which contact has been made, who are developing STPs; the FFCAct Clearinghouse Fact Sheet and; additional hard copy forms to be used to populate the database. This report contains 50 abstracts related to the Radioactive Waste Technical Support Program.

  17. Subwog 12-D tritium technology meeting. Abstracts

    SciTech Connect

    Parker, M.J.; Addis, R.P.

    1991-12-31

    The first Subwog 12-D Tritium Technology Meeting was held at the Westinghouse Savannah River Site during the week of May 21, 1990. Subwog 12-D was created as a subwog of JOWOG 12 to address the need to understand tritium applications throughout the entire weapons complex. This includes weapons related concerns, but is primarily intended to cover tritium production and handling, environmental, safety and health issues, compatibility with materials in general; and facility design, commissioning and decommissioning activities. Tritium technology issues discussed included the physical and chemical properties, kinetics, storage, reservoir loading techniques, isotope exchange, radiolysis/aging, process and handling technology, compatibility, purification and filtering, analysis, monitoring methods, function testing, packaging and shipping, environmental and operational safety, facility design and safety, glovebox atmosphere clean-up systems, glovebox/facility decommissioning, tritium production target materials, and tritium recovery. This document provides a collection of most of the unclassified extended abstracts and abstracts presented at Subwog 12-D.

  18. Using Group Explorer in teaching abstract algebra

    NASA Astrophysics Data System (ADS)

    Schubert, Claus; Gfeller, Mary; Donohue, Christopher

    2013-04-01

    This study explores the use of Group Explorer in an undergraduate mathematics course in abstract algebra. The visual nature of Group Explorer in representing concepts in group theory is an attractive incentive to use this software in the classroom. However, little is known about students' perceptions on this technology in learning concepts in abstract algebra. A total of 26 participants in an undergraduate course studying group theory were surveyed regarding their experiences using Group Explorer. Findings indicate that all participants believed that the software was beneficial to their learning and described their attitudes regarding the software in terms of using the technology and its helpfulness in learning concepts. A multiple regression analysis reveals that representational fluency of concepts with the software correlated significantly with participants' understanding of group concepts yet, participants' attitudes about Group Explorer and technology in general were not significant factors.

  19. HBCUs Research Conference Agenda and Abstracts

    NASA Technical Reports Server (NTRS)

    Dutta, Sunil (Compiler)

    1998-01-01

    The purpose of this Historically Black Colleges and Universities (HBCUs) Research Conference was to provide an opportunity for principal investigators and their students to present research progress reports. The abstracts included in this report indicate the range and quality of research topics such as aeropropulsion, space propulsion, space power, fluid dynamics, designs, structures and materials being funded through grants from Lewis Research Center to HBCUs. The conference generated extensive networking between students, principal investigators, Lewis technical monitors, and other Lewis researchers.

  20. Heat Pipe Technology: A bibliography with abstracts

    NASA Technical Reports Server (NTRS)

    1974-01-01

    This bibliography lists 149 references with abstracts and 47 patents dealing with applications of heat pipe technology. Topics covered include: heat exchangers for heat recovery; electrical and electronic equipment cooling; temperature control of spacecraft; cryosurgery; cryogenic, cooling; nuclear reactor heat transfer; solar collectors; laser mirror cooling; laser vapor cavitites; cooling of permafrost; snow melting; thermal diodes variable conductance; artery gas venting; and venting; and gravity assisted pipes.

  1. HBCUs Research Conference Agenda and Abstracts

    NASA Technical Reports Server (NTRS)

    Dutta, Sunil (Compiler)

    1997-01-01

    The purpose of this Historically Black Colleges and Universities (HBCUS) Research Conference was to provide an opportunity for principal investigators and their students to present research progress reports. The abstracts included in this report indicate the range and quality of research topics such as aeropropulsion, space propulsion, space power, fluid dynamics, designs, structures and materials being funded through grants from Lewis Research Center to HBCUS. The conference generated extensive networking between students, principal investigators, Lewis technical monitors, and other Lewis researchers.

  2. Artificial Intelligence Technical Paper Abstracts 1991

    DTIC Science & Technology

    1992-07-08

    Strategy Acquisition with Genetic Algorithms , John J. Grefenstene 28 [ ] AIC-91-014 Lamarckian Learning in Multi-agent Environments, John J...LEARNING Title: Is the Genetic Algorithm a Cooperative Leamner? Author(s): Helen G. Cobb E-mail Address: cobb@aic.nrl.navy.mil Citation: submitted to...the Second Workshop on Foundations of Genetic Algorithms (FOGA-92) Date: Forthcoming, 1992 AIC Report No.: AIC-91-001 Abstract This paper begins to

  3. Recombination at the DNA level. Abstracts

    SciTech Connect

    Not Available

    1984-01-01

    Abstracts of papers in the following areas are presented: (1) chromosome mechanics; (2) yeast systems; (3) mammalian homologous recombination; (4) transposons; (5) Mu; (6) plant transposons/T4 recombination; (7) topoisomerase, resolvase, and gyrase; (8) Escherichia coli general recombination; (9) recA; (10) repair; (11) eucaryotic enzymes; (12) integration and excision of bacteriophage; (13) site-specific recombination; and (14) recombination in vitro. (ACR)

  4. Cryogenic adhesives and sealants: Abstracted publications

    NASA Technical Reports Server (NTRS)

    Williamson, F. R.; Olien, N. A.

    1977-01-01

    Abstracts of primary documents containing original experimental data on the properties of adhesives and sealants at cryogenic temperatures are presented. The most important references mentioned in each document are cited. In addition, a brief annotation is given for documents considered secondary in nature, such as republications or variations of original reports, progress reports leading to final reports included as primary documents, and experimental data on adhesive properties at temperatures between about 130 K and room temperature.

  5. Analysis of Vietnamization: Data Abstract. Volume 3

    DTIC Science & Technology

    1973-07-01

    AD/A-005 361 ANALYSIS OF VILTNAMIZATION: DATA ABS TRACT William G. Prince 0. 0 Bendix Corporation ca) V) Prepared for: Defense Advanced Research...DISSRISUTtOlN 8TATGEMENT Quali fied requestors may obcain copies of this report from D)C: It SURWLCMENTARV N6TES2 t TPONSORINGI %"LITANY ACTIVIY Defense Advanced ...BSR 4033 ANALYSIS OF VIETNAMIZATION: -"O DATA ABSTRACT Final Report Volume III Sponsored by: Defense Advanced Research Projects Agency ARPA Order No

  6. HBCUs Research Conference agenda and abstracts

    NASA Technical Reports Server (NTRS)

    Dutta, Sunil (Compiler)

    1995-01-01

    The purpose of this Historically Black Colleges and Universities (HBCUs) Research conference was to provide an opportunity for principal investigators and their students to present research progress reports. The abstracts included in this report indicate the range and quality of research topics such as aeropropulsion, space propulsion, space power, fluid dynamics, designs, structures and materials being funded through grants from Lewis Research Center to HBCUs. The conference generated extensive networking between students, principal investigators, Lewis technical monitors, and other Lewis researchers.

  7. Youth Initiatives.

    ERIC Educational Resources Information Center

    Employment and Training Administration (DOL), Washington, DC. Office of Youth Programs.

    Summarizing the first eight months of the planning, design, and implementation of the new federal youth programs created by the Youth Employment and Demonstration Projects Act of 1977 (YEDPA) and the efforts for expansion and enrichment of the Job Corps, this report explains the charters of the two projects and their initial successes in and…

  8. Implementing abstract multigrid or multilevel methods

    NASA Technical Reports Server (NTRS)

    Douglas, Craig C.

    1993-01-01

    Multigrid methods can be formulated as an algorithm for an abstract problem that is independent of the partial differential equation, domain, and discretization method. In such an abstract setting, problems not arising from partial differential equations can be treated. A general theory exists for linear problems. The general theory was motivated by a series of abstract solvers (Madpack). The latest version was motivated by the theory. Madpack now allows for a wide variety of iterative and direct solvers, preconditioners, and interpolation and projection schemes, including user callback ones. It allows for sparse, dense, and stencil matrices. Mildly nonlinear problems can be handled. Also, there is a fast, multigrid Poisson solver (two and three dimensions). The type of solvers and design decisions (including language, data structures, external library support, and callbacks) are discussed. Based on the author's experiences with two versions of Madpack, a better approach is proposed. This is based on a mixed language formulation (C and FORTRAN + preprocessor). Reasons for not using FORTRAN, C, or C++ (individually) are given. Implementing the proposed strategy is not difficult.

  9. A Semantic Theory of Abstractions: A Preliminary Report

    NASA Technical Reports Server (NTRS)

    Nayak, P. Pandurang; Levy, Alon Y.; Lum, Henry, Jr. (Technical Monitor)

    1994-01-01

    In this paper we present a semantic theory of abstractions based on viewing abstractions as interpretations between theories. This theory captures important aspects of abstractions not captured in the theory of abstractions presented by Giunchiglia and Walsh. Instead of viewing abstractions as syntactic mappings, we view abstractions as a two step process: the intended domain model is first abstracted and then a set of (abstract) formulas is constructed to capture the abstracted domain model. Viewing and justifying abstractions as model level transformations is both natural and insightful. We provide a precise characterization of the abstract theory that exactly implements the intended abstraction, and show that this theory, while being axiomatizable, is not always finitely axiomatizable. A simple corollary of the latter result disproves a conjecture made by Tenenberg that if a theory is finitely axiomatizable, then predicate abstraction of that theory leads to a finitely axiomatizable theory.

  10. Mass Communication: Abstracts of Doctoral Dissertations Published in "Dissertation Abstracts International," July through December 1979 (Vol. 40 Nos. 1 through 6).

    ERIC Educational Resources Information Center

    ERIC Clearinghouse on Reading and Communication Skills, Urbana, IL.

    This collection of abstracts is part of a continuing series providing information on recent doctoral dissertations. The 58 titles deal with a variety of topics, including the following: value, attitude, and behavior change initiated by interpersonal and mass media; television and the school; bridal magazines from 1967 to 1977; interpersonal…

  11. Business and Organizational Communication: Abstracts of Doctoral Dissertations Published in "Dissertation Abstracts International," January through June 1983 (Vol. 43 Nos. 7 through 12).

    ERIC Educational Resources Information Center

    ERIC Clearinghouse on Reading and Communication Skills, Urbana, IL.

    This collection of abstracts is part of a continuing series providing information on recent doctoral dissertations. The 14 titles deal with a variety of topics, including the following: (1) the effects of verbal and nonverbal affiliation on initial interactions between handicapped and nonhandicapped persons during employment interviews; (2)…

  12. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 05)

    NASA Technical Reports Server (NTRS)

    1974-01-01

    This bibliography is issued in two sections: Section 1 - Abstracts, and section 2 - Indexes. The abstract section cites 217 patents and applications for patent introduced into the NASA scientific and technical information system during the period of January 1974 through June 1974. Each entry consists of a citation, an abstract, and, in most cases, a key illustration selected from the patent or application for patent. The index section contains entries for 2653 patent and application for patent citations covering the period May 1969 through June 1974. The index section contains five indexes -- subject, inventor, source, number and accession number.

  13. Fluorine atom abstraction by Si(100). I. Experimental

    NASA Astrophysics Data System (ADS)

    Tate, M. R.; Gosalvez-Blanco, D.; Pullman, D. P.; Tsekouras, A. A.; Li, Y. L.; Yang, J. J.; Laughlin, K. B.; Eckman, S. C.; Bertino, M. F.; Ceyer, S. T.

    1999-08-01

    In the interaction of low energy F2 with Si(100) at 250 K, a dissociative chemisorption mechanism called atom abstraction is identified in which only one of the F atoms is adsorbed while the other F atom is scattered into the gas phase. The dynamics of atom abstraction are characterized via time-of-flight measurements of the scattered F atoms. The F atoms are translationally hyperthermal but only carry a small fraction (˜3%) of the tremendous exothermicity of the reaction. The angular distribution of F atoms is unusually broad for the product of an exothermic reaction. These results suggest an "attractive" interaction potential between F2 and the Si dangling bond with a transition state that is not constrained geometrically. These results are in disagreement with the results of theoretical investigations implying that the available potential energy surfaces are inadequate to describe the dynamics of this gas-surface interaction. In addition to single atom abstraction, two atom adsorption, a mechanism analogous to classic dissociative chemisorption in which both F atoms are adsorbed onto the surface, is also observed. The absolute probability of the three scattering channels (single atom abstraction, two atom adsorption, and unreactive scattering) for an incident F2 are determined as a function of F2 exposure. The fluorine coverage is determined by integrating the reaction probabilities over F2 exposure, and the reaction probabilities are recast as a function of fluorine coverage. Two atom adsorption is the dominant channel [P2=0.83±0.03(95%, N=9)] in the limit of zero coverage and decays monotonically to zero. Single atom abstraction is the minor channel (P1=0.13±0.03) at low coverage but increases to a maximum (P1=0.35±0.08) at about 0.5 monolayer (ML) coverage before decaying to zero. The reaction ceases at 0.94±0.11(95%, N=9) ML. Thermal desorption and helium diffraction confirm that the dangling bonds are the abstraction and adsorption sites. No Si lattice

  14. Overview of the biomedical and environmental programs at the Oak Ridge National Laboratory. [Lead abstract

    SciTech Connect

    Pfuderer, H.A.; Moody, J.B.

    1981-07-01

    Separate abstracts were prepared for each of the 6 chapters presented by the six divisions involved in the Biomedical and Environmental Sciences Program at Oak Ridge National Laboratory. The introduction is not covered by an abstract and deals with the environmental, health and safety considerations of energy technology decisions, the major initiatives now being taken by these 6 divisions, and recent major accomplishments in the biomedical and environmental science program. (KRM)

  15. SCB initiator

    DOEpatents

    Bickes Jr., Robert W.; Renlund, Anita M.; Stanton, Philip L.

    1994-11-01

    A detonator for high explosives initiated by mechanical impact includes a cylindrical barrel, a layer of flyer material mechanically covering the barrel at one end, and a semiconductor bridge ignitor including a pair of electrically conductive pads connected by a semiconductor bridge. The bridge is in operational contact with the layer, whereby ignition of said bridge forces a portion of the layer through the barrel to detonate the explosive. Input means are provided for igniting the semiconductor bridge ignitor.

  16. SCB initiator

    SciTech Connect

    Bickes, Jr., Robert W.; Renlund, Anita M.; Stanton, Philip L.

    1994-01-01

    A detonator for high explosives initiated by mechanical impact includes a cylindrical barrel, a layer of flyer material mechanically covering the barrel at one end, and a semiconductor bridge ignitor including a pair of electrically conductive pads connected by a semiconductor bridge. The bridge is in operational contact with the layer, whereby ignition of said bridge forces a portion of the layer through the barrel to detonate the explosive. Input means are provided for igniting the semiconductor bridge ignitor.

  17. Reporting quality of randomized controlled trial abstracts published in leading laser medicine journals: an assessment using the CONSORT for abstracts guidelines.

    PubMed

    Jin, Lu; Hua, Fang; Cao, Qiang

    2016-11-01

    The objectives of this study were to assess the reporting quality of randomized controlled trial (RCT) abstracts published in leading laser medicine journals and investigate the association between potential predictors and reporting quality. The official online archives of four leading laser medicine journals were hand-searched to identify RCTs published in 2014 and 2015. A reporting quality assessment was carried out using the original 16-item CONsolidated Standards Of Reporting Trials (CONSORT) for Abstracts checklist. For each abstract, an overall CONSORT score (OCS) was calculated (score range, 0 to 16). Univariable and multivariable linear regression analyses were performed to identify significant predictors of reporting quality. Chi-square (or Fisher's exact) tests were used to analyze the adequate reporting rate of each quality item by specialty area. A total of 129 RCT abstracts were included and assessed. The mean OCS was 4.5 (standard deviation, 1.3). Only three quality items (interventions, objective, conclusions) were reported adequately in most abstracts (>80 %). No abstract adequately reported results for the primary outcome, source of funding, and status of the trial. In addition, sufficient reporting of participants, outcome in the methods section, randomization, and trial registration was rare (<5 %). According to multivariable linear regression analysis, the specialty area of RCT abstracts was significantly associated with their reporting quality (P = 0.008). The reporting quality of RCT abstracts published in leading laser medicine journals is suboptimal. Joint efforts by authors, editors, and other stakeholders in the field to improve trial abstract reporting are needed.

  18. Divvy Economies Based On (An Abstract) Temperature

    NASA Astrophysics Data System (ADS)

    Collins, Dennis G.

    2004-04-01

    The Leontief Input-Output economic system can provide a model for a one-parameter family of economic systems based on an abstract temperature T. In particular, given a normalized input-output matrix R and taking R= R(1), a family of economic systems R(1/T)=R(α) is developed that represents heating (T>1) and cooling (T<1) of the economy relative to T=1. .The economy for a given value of T represents the solution of a constrained maximum entropy problem.

  19. Solar thermal components. A bibliography with abstracts

    NASA Technical Reports Server (NTRS)

    Bozman, W. R. (Editor)

    1979-01-01

    This bibliographic series cites and abstracts literature and technical papers on components applied to solar thermal energy utilization. The quarterly volumes are divided into ten categories: material properties; flat plat collectors; concentrating collectors; thermal storage; heat pumps; coolers and heat exchangers; solar ponds and distillation; greenhouses; process pleat; and irrigation pumps. Each quarterly volume is compiled from a wide variety of data bases, report literature, technical briefs, journal articles and other traditional and non traditional sources. The Technology Application Center maintains a library containing many of the articles and publications referenced in the series.

  20. The Lyncis Two for One Special (Abstract)

    NASA Astrophysics Data System (ADS)

    Joner, M.; Hintz, E.

    2015-12-01

    (Abstract only) The pulsating delta Scuti star AN Lyn and the near contact binary UU Lyn are conveniently located at high declination in the northern constellation of Lynx. These variable stars are about 15 arc minutes apart in the sky and differ in average brightness by roughly one magnitude. This combination makes it fairly straightforward to secure photometric data on both stars at the same time using a common set of comparison stars. We present observations made at the BYU West Mountain Observatory during the spring of 2015 and outline some preliminary conclusions that can be drawn about these distinctly different variable stars.

  1. Current Abstracts Nuclear Reactors and Technology

    SciTech Connect

    Bales, J.D.; Hicks, S.C.

    1993-01-01

    This publication Nuclear Reactors and Technology (NRT) announces on a monthly basis the current worldwide information available from the open literature on nuclear reactors and technology, including all aspects of power reactors, components and accessories, fuel elements, control systems, and materials. This publication contains the abstracts of DOE reports, journal articles, conference papers, patents, theses, and monographs added to the Energy Science and Technology Database during the past month. Also included are US information obtained through acquisition programs or interagency agreements and international information obtained through acquisition programs or interagency agreements and international information obtained through the International Energy Agency`s Energy Technology Data Exchange or government-to-government agreements. The digests in NRT and other citations to information on nuclear reactors back to 1948 are available for online searching and retrieval on the Energy Science and Technology Database and Nuclear Science Abstracts (NSA) database. Current information, added daily to the Energy Science and Technology Database, is available to DOE and its contractors through the DOE Integrated Technical Information System. Customized profiles can be developed to provide current information to meet each user`s needs.

  2. DSNF and other waste form degradation abstraction

    SciTech Connect

    Thornton, Thomas A.

    2000-12-20

    The purpose of this analysis/model report (AMR) is to select and/or abstract conservative degradation models for DOE-(US. Department of Energy) owned spent nuclear fuel (DSNF) and the immobilized ceramic plutonium (Pu) disposition waste forms for application in the proposed monitored geologic repository (MGR) postclosure Total System Performance Assessment (TSPA). Application of the degradation models abstracted herein for purposes other than TSPA should take into consideration the fact that they are, in general, very conservative. Using these models, the forward reaction rate for the mobilization of radionuclides, as solutes or colloids, away from the waste fondwater interface by contact with repository groundwater can then be calculated. This forward reaction rate generally consists of the dissolution reaction at the surface of spent nuclear fuel (SNF) in contact with water, but the degradation models, in some cases, may also include and account for the physical disintegration of the SNF matrix. The models do not, however, account for retardation, precipitation, or inhibition of the migration of the mobilized radionuclides in the engineered barrier system (EBS). These models are based on the assumption that all components of the DSNF waste form are released congruently with the degradation of the matrix.

  3. Processing abstract language modulates motor system activity.

    PubMed

    Glenberg, Arthur M; Sato, Marc; Cattaneo, Luigi; Riggio, Lucia; Palumbo, Daniele; Buccino, Giovanni

    2008-06-01

    Embodiment theory proposes that neural systems for perception and action are also engaged during language comprehension. Previous neuroimaging and neurophysiological studies have only been able to demonstrate modulation of action systems during comprehension of concrete language. We provide neurophysiological evidence for modulation of motor system activity during the comprehension of both concrete and abstract language. In Experiment 1, when the described direction of object transfer or information transfer (e.g., away from the reader to another) matched the literal direction of a hand movement used to make a response, speed of responding was faster than when the two directions mismatched (an action-sentence compatibility effect). In Experiment 2, we used single-pulse transcranial magnetic stimulation to study changes in the corticospinal motor pathways to hand muscles while reading the same sentences. Relative to sentences that do not describe transfer, there is greater modulation of activity in the hand muscles when reading sentences describing transfer of both concrete objects and abstract information. These findings are discussed in relation to the human mirror neuron system.

  4. Neural Representations of Emotion Are Organized around Abstract Event Features

    PubMed Central

    Skerry, Amy E.; Saxe, Rebecca

    2016-01-01

    Summary Research on emotion attribution has tended to focus on the perception of overt expressions of at most five or six basic emotions. However, our ability to identify others' emotional states is not limited to perception of these canonical expressions. Instead, we make fine-grained inferences about what others feel based on the situations they encounter, relying on knowledge of the eliciting conditions for different emotions. In the present research, we provide convergent behavioral and neural evidence concerning the representations underlying these concepts. First, we find that patterns of activity in mentalizing regions contain information about subtle emotional distinctions conveyed through verbal descriptions of eliciting situations. Second, we identify a space of abstract situation features that well captures the emotion discriminations subjects make behaviorally and show that this feature space outperforms competing models in capturing the similarity space of neural patterns in these regions. Together, the data suggest that our knowledge of others' emotions is abstract and high dimensional, that brain regions selective for mental state reasoning support relatively subtle distinctions between emotion concepts, and that the neural representations in these regions are not reducible to more primitive affective dimensions such as valence and arousal. PMID:26212878

  5. Neural representations of emotion are organized around abstract event features.

    PubMed

    Skerry, Amy E; Saxe, Rebecca

    2015-08-03

    Research on emotion attribution has tended to focus on the perception of overt expressions of at most five or six basic emotions. However, our ability to identify others' emotional states is not limited to perception of these canonical expressions. Instead, we make fine-grained inferences about what others feel based on the situations they encounter, relying on knowledge of the eliciting conditions for different emotions. In the present research, we provide convergent behavioral and neural evidence concerning the representations underlying these concepts. First, we find that patterns of activity in mentalizing regions contain information about subtle emotional distinctions conveyed through verbal descriptions of eliciting situations. Second, we identify a space of abstract situation features that well captures the emotion discriminations subjects make behaviorally and show that this feature space outperforms competing models in capturing the similarity space of neural patterns in these regions. Together, the data suggest that our knowledge of others' emotions is abstract and high dimensional, that brain regions selective for mental state reasoning support relatively subtle distinctions between emotion concepts, and that the neural representations in these regions are not reducible to more primitive affective dimensions such as valence and arousal.

  6. Decoding abstract and concrete concept representations based on single-trial fMRI data.

    PubMed

    Wang, Jing; Baucom, Laura B; Shinkareva, Svetlana V

    2013-05-01

    Previously, multi-voxel pattern analysis has been used to decode words referring to concrete object categories. In this study we investigated if single-trial-based brain activity was sufficient to distinguish abstract (e.g., mercy) versus concrete (e.g., barn) concept representations. Multiple neuroimaging studies have identified differences in the processing of abstract versus concrete concepts based on the averaged activity across time by using univariate methods. In this study we used multi-voxel pattern analysis to decode functional magnetic resonance imaging (fMRI) data when participants perform a semantic similarity judgment task on triplets of either abstract or concrete words with similar meanings. Classifiers were trained to identify individual trials as concrete or abstract. Cross-validated accuracies for classifying trials as abstract or concrete were significantly above chance (P < 0.05) for all participants. Discriminating information was distributed in multiple brain regions. Moreover, accuracy of identifying single trial data for any one participant as abstract or concrete was also reliably above chance (P < 0.05) when the classifier was trained solely on data from other participants. These results suggest abstract and concrete concepts differ in representations in terms of neural activity patterns during a short period of time across the whole brain.

  7. A tale of hydrogen abstraction, initially detected via X-ray diffraction.

    PubMed

    Hui, Alice K; Chen, Chun Hsing; Terwilliger, Adam M; Lord, Richard L; Caulton, Kenneth G

    2014-03-01

    Reaction of a bis-tetrazinyl pyridine pincer ligand, btzp, with a vanadium(III) reagent gives not a simple adduct but dichlorido{3-methyl-6-[6-(6-methyl-1,2,4,5-tetrazin-3-yl-κN(2))pyridin-2-yl-κN]-1,4-dihydro-1,2,4,5-tetrazin-1-yl-κN(1)}oxidovanadium(IV) acetonitrile 2.5-solvate, [V(C11H10N9)Cl2O]·2.5CH3CN, a species which X-ray diffraction reveals to have one H atom added to one of the two tetrazinyl rings. This H atom was first revealed by a short intermolecular N...Cl contact in the unit cell and subsequently established, from difference maps, to be associated with a hydrogen bond. One chloride ligand has also been replaced by an oxide ligand in this synthetic reaction. This formula for the complex, [V(Hbtzp)Cl2O], leaves open the question of both ligand oxidation state and spin state. A computational study of all isomeric locations of the H atom shows the similarity of their energies, which is subject to perturbation by intermolecular hydrogen bonding found in X-ray work on the solid state. These density functional calculations reveal that the isomer with the H atom located as found in the solid state contains a neutral radical Hbtzp ligand and tetravalent d(1) V center, but that these two unpaired electrons are more stable as an open-shell singlet and hence antiferromagnetically coupled.

  8. Initial Abstraction and Curve Numbers in a Semiarid Watershed in Southeastern Arizona

    EPA Science Inventory

    The Soil Conservation Service curve number estimates of direct runoff from rainfall for semiarid catchments can be inaccurate. Investigation of the Walnut Gulch Experimental Watershed (Southeastern Arizona) and its 10 nested catchments determined that the inaccuracy is due to an ...

  9. The Common Element Effect of Abstract-to-Abstract Mapping in Language Processing.

    PubMed

    Chen, Xuqian; Wang, Guixiang; Liang, Yuchan

    2016-01-01

    Since the 1990s, there has been much discussion about how concepts are learned and processed. Many researchers believe that the experienced bodily states (i.e., embodied experiences) should be an important factor that affects concepts' learning and use, and metaphorical mappings between abstract concepts, such as TIME and POWER, and concrete concepts, such as SPATIAL ORIENTATION, STRUCTURED EXPERIENCEs, etc., suggest the abstract-concrete concepts' connections. In most of the recent literature, we can find common elements (e.g., concrete concepts) shared by different abstract-concrete metaphorical expressions. Therefore, we assumed that mappings might also be found between two abstract concepts that share common elements, though they have no symbolic connections. In the present study, two lexical decision tasks were arranged and the priming effect between TIME and ABSTRACT ACTIONs was used as an index to test our hypothesis. Results showed a robust priming effect when a target verb and its prime belonged to the same duration type (TIME consistent condition). These findings suggest that mapping between concepts was affected by common elements. We propose a dynamic model in which mappings between concepts are influenced by common elements, including symbolic or embodied information. What kind of elements (linguistic or embodied) can be used would depend on how difficult it is for a concept to be learned or accessed.

  10. The Common Element Effect of Abstract-to-Abstract Mapping in Language Processing

    PubMed Central

    Chen, Xuqian; Wang, Guixiang; Liang, Yuchan

    2016-01-01

    Since the 1990s, there has been much discussion about how concepts are learned and processed. Many researchers believe that the experienced bodily states (i.e., embodied experiences) should be an important factor that affects concepts’ learning and use, and metaphorical mappings between abstract concepts, such as TIME and POWER, and concrete concepts, such as SPATIAL ORIENTATION, STRUCTURED EXPERIENCEs, etc., suggest the abstract-concrete concepts’ connections. In most of the recent literature, we can find common elements (e.g., concrete concepts) shared by different abstract-concrete metaphorical expressions. Therefore, we assumed that mappings might also be found between two abstract concepts that share common elements, though they have no symbolic connections. In the present study, two lexical decision tasks were arranged and the priming effect between TIME and ABSTRACT ACTIONs was used as an index to test our hypothesis. Results showed a robust priming effect when a target verb and its prime belonged to the same duration type (TIME consistent condition). These findings suggest that mapping between concepts was affected by common elements. We propose a dynamic model in which mappings between concepts are influenced by common elements, including symbolic or embodied information. What kind of elements (linguistic or embodied) can be used would depend on how difficult it is for a concept to be learned or accessed. PMID:27822192

  11. VEST: Abstract vector calculus simplification in Mathematica

    NASA Astrophysics Data System (ADS)

    Squire, J.; Burby, J.; Qin, H.

    2014-01-01

    We present a new package, VEST (Vector Einstein Summation Tools), that performs abstract vector calculus computations in Mathematica. Through the use of index notation, VEST is able to reduce three-dimensional scalar and vector expressions of a very general type to a well defined standard form. In addition, utilizing properties of the Levi-Civita symbol, the program can derive types of multi-term vector identities that are not recognized by reduction, subsequently applying these to simplify large expressions. In a companion paper Burby et al. (2013) [12], we employ VEST in the automation of the calculation of high-order Lagrangians for the single particle guiding center system in plasma physics, a computation which illustrates its ability to handle very large expressions. VEST has been designed to be simple and intuitive to use, both for basic checking of work and more involved computations.

  12. [Special methodology, qualitative methods and abstract concepts].

    PubMed

    Delgado, Ana R

    2010-08-01

    Generally speaking, this paper comments on the role of qualitative methods in scientific psychology. To begin with, general and special methodology are defined; then, the main uses of qualitative methods are described and the focus of the paper on the study of meaning and of abstract concepts in the context of embodied cognition is justified. It is emphasized that three uses of qualitative methods converge in the study of embodied cognition: (1) classification, given that it is centered on concepts, (2) discovery, because theories are not yet well articulated and inductive effort is required, and (3) the study of meaning. The final recommendation is to profit from the opportunity of constructing special techniques that the transformation of cognitive psychology is favoring; in this context, varieties of emotion become a privileged object of study.

  13. Model Checking Abstract PLEXIL Programs with SMART

    NASA Technical Reports Server (NTRS)

    Siminiceanu, Radu I.

    2007-01-01

    We describe a method to automatically generate discrete-state models of abstract Plan Execution Interchange Language (PLEXIL) programs that can be analyzed using model checking tools. Starting from a high-level description of a PLEXIL program or a family of programs with common characteristics, the generator lays the framework that models the principles of program execution. The concrete parts of the program are not automatically generated, but require the modeler to introduce them by hand. As a case study, we generate models to verify properties of the PLEXIL macro constructs that are introduced as shorthand notation. After an exhaustive analysis, we conclude that the macro definitions obey the intended semantics and behave as expected, but contingently on a few specific requirements on the timing semantics of micro-steps in the concrete executive implementation.

  14. Interfacing microbiology and biotechnology. Conference abstracts

    SciTech Connect

    Maupin, Julia A.

    2001-05-19

    The Interfacing Microbiology and Biotechnology Conference was attended by over 100 faculty, post-docs, students, and research scientists from the US, Europe, and Latin America. The conference successfully stimulated communication and the dissemination of knowledge among scientists involved in basic and applied research. The focus of the conference was on microbial physiology and genetics and included sessions on C1 metabolism, archaeal metabolism, proteases and chaperones, gene arrays, and metabolic engineering. The meeting provided the setting for in-depth discussions between scientists who are internationally recognized for their research in these fields. The following objectives were met: (1) The promotion of interaction and future collaborative projects among scientists involved in basic and applied research which incorporates microbial physiology, genetics, and biochemistry; (2) the facilitation of communication of new research findings through seminars, posters, and abstracts; (3 ) the stimulation of enthusiasm and education among participants including graduate and undergraduate students.

  15. Gasohol sourcebook - Literature survey and abstracts

    NASA Astrophysics Data System (ADS)

    Cheremisinoff, N. P.; Cheremisinoff, P. N.

    A review is provided of biomass and bioconversion technology literature, giving particular attention to gasohol and related fuels. Literature cited and reviewed covers a variety of subjects such as properties of biomass, overviews of bioconversion technologies, toxic and hazardous properties of alcohols, and sources of biomass. Source listings and selected abstracts are provided back to 1965. Both U.S. government reports and journal publications are listed. Foreign publications are also included. A listing is presented of both U.S. and foreign patents on various subjects related to bioconversion technology and gasohol production. Ethanol and methanol production is considered along with automotive and other fuel uses, the production of chemical feedstocks, and the economics of alcohol production.

  16. eta Carinae Continues to Evolve (Abstract)

    NASA Astrophysics Data System (ADS)

    Martin, J. C.

    2015-06-01

    (Abstract only) Eta Carinae affords us a unique opportunity to study the pre-supernova evolution of the most massive stars. For at least the last half century, it has maintained a 5.5-year spectroscopic cycle that culminates with abrupt decreases in the strong stellar wind emission features. Over the last 15 years, the star has brightened at an accelerated rate and altered its spectrum, in addition to the spectroscopic cycle, indicating an ongoing change in state. We present Hubble Space Telescope spectroscopy and synthetic photometry from the most recent spectroscopic event (2014.5) that shows notable differences with past events and provides clues to the on-going evolution of the star.

  17. VEST: Abstract Vector Calculus Simplification in Mathematica

    SciTech Connect

    J. Squire, J. Burby and H. Qin

    2013-03-12

    We present a new package, VEST (Vector Einstein Summation Tools), that performs abstract vector calculus computations in Mathematica. Through the use of index notation, VEST is able to reduce scalar and vector expressions of a very general type using a systematic canonicalization procedure. In addition, utilizing properties of the Levi-Civita symbol, the program can derive types of multi-term vector identities that are not recognized by canonicalization, subsequently applying these to simplify large expressions. In a companion paper [1], we employ VEST in the automation of the calculation of Lagrangians for the single particle guiding center system in plasma physics, a computation which illustrates its ability to handle very large expressions. VEST has been designed to be simple and intuitive to use, both for basic checking of work and more involved computations. __________________________________________________

  18. First LDEF Post-Retrieval Symposium abstracts

    NASA Technical Reports Server (NTRS)

    Levine, Arlene S. (Compiler)

    1991-01-01

    The LDE facility was designed to better understand the environments of space and the effects of prolonged exposure in these environments on future spacecraft. The symposium abstracts presented here are organized according to the symposium agenda into five sessions. The first session provides an overview of the LDEF, the experiments, the mission, and the natural and induced environments the spacecraft and experiments encountered during the mission. The second session presents results to date from studies to better define the environments of near-Earth space. The third session addresses studies of the effects of the space environments on spacecraft materials. The fourth session addresses studies of the effects of the space environments on spacecraft systems. And the fifth session addresses other subjects such as results of the LDEF life science and crystal growth experiments.

  19. Abstraction in art with implications for perception.

    PubMed Central

    Zimmer, Robert

    2003-01-01

    The relationship between people and art is complex and intriguing. Of course, artworks are our creations; but in interesting and important ways, we are also created by our artworks. Our sense of the world is informed by the art we make and by the art we inherit and value, works that, in themselves, encode others' world views. This two-way effect is deeply rooted and art encodes and affects both a culture's ways of perceiving the world and its ways of remaking the world it perceives. The purpose of this paper is to indicate ways in which a study of abstraction in art can be used to discover insights into, to quote the call for papers for this issue, 'our perception of the world, acquired through experience' and 'the way concepts are formed and manipulated to achieve goals'. PMID:12903671

  20. Fast ensemble representations for abstract visual impressions

    PubMed Central

    Leib, Allison Yamanashi; Kosovicheva, Anna; Whitney, David

    2016-01-01

    Much of the richness of perception is conveyed by implicit, rather than image or feature-level, information. The perception of animacy or lifelikeness of objects, for example, cannot be predicted from image level properties alone. Instead, perceiving lifelikeness seems to be an inferential process and one might expect it to be cognitively demanding and serial rather than fast and automatic. If perceptual mechanisms exist to represent lifelikeness, then observers should be able to perceive this information quickly and reliably, and should be able to perceive the lifelikeness of crowds of objects. Here, we report that observers are highly sensitive to the lifelikeness of random objects and even groups of objects. Observers' percepts of crowd lifelikeness are well predicted by independent observers' lifelikeness judgements of the individual objects comprising that crowd. We demonstrate that visual impressions of abstract dimensions can be achieved with summary statistical representations, which underlie our rich perceptual experience. PMID:27848949

  1. Next generation epics interface to abstract data.

    SciTech Connect

    Hill, J. O.; Lange, R.

    2001-01-01

    The set of externally visible properties associated with process variables in the Experimental Physics and Industrial Control System (EPICS) is predefined in the EPICS base distribution and is therefore not extensible by plug-compatible applications. We believe that this approach, while practical for early versions of the system with a smaller user base, is now severely limiting expansion of the high-level application tool set for EPICS. To eliminate existing barriers, we propose a new C++ based interface to abstract containerized data. This paper describes the new interface, its application to message passing in distributed systems, its application to direct communication between tightly coupled programs co-resident in an address space, and its paramount position in an emerging role for EPICS -- the integration of dissimilar systems.

  2. New abstraction networks and a new visualization tool in support of auditing the SNOMED CT content.

    PubMed

    Geller, James; Ochs, Christopher; Perl, Yehoshua; Xu, Junchuan

    2012-01-01

    Medical terminologies are large and complex. Frequently, errors are hidden in this complexity. Our objective is to find such errors, which can be aided by deriving abstraction networks from a large terminology. Abstraction networks preserve important features but eliminate many minor details, which are often not useful for identifying errors. Providing visualizations for such abstraction networks aids auditors by allowing them to quickly focus on elements of interest within a terminology. Previously we introduced area taxonomies and partial area taxonomies for SNOMED CT. In this paper, two advanced, novel kinds of abstraction networks, the relationship-constrained partial area subtaxonomy and the root-constrained partial area subtaxonomy are defined and their benefits are demonstrated. We also describe BLUSNO, an innovative software tool for quickly generating and visualizing these SNOMED CT abstraction networks. BLUSNO is a dynamic, interactive system that provides quick access to well organized information about SNOMED CT.

  3. The Notion of Reducing Abstraction in Quadratic Functions

    ERIC Educational Resources Information Center

    Eraslan, Ali

    2008-01-01

    One possible approach students can cope with abstract algebra concepts is reducing abstraction. This notion occurs when learners are unable to adopt mental strategies as they deal with abstraction level of a given task. To make these concepts mentally accessible for themselves, learners unconsciously reduce the level of the abstraction of the…

  4. PS2-06: Best Practices for Advancing Multi-site Chart Abstraction Research

    PubMed Central

    Blick, Noelle; Cole, Deanna; King, Colleen; Riordan, Rick; Von Worley, Ann; Yarbro, Patty

    2012-01-01

    Background/Aims Multi-site chart abstraction studies are becoming increasingly common within the HMORN. Differences in systems among HMORN sites can pose significant obstacles to the success of these studies. It is therefore crucial to standardize abstraction activities by following best practices for multi-site chart abstraction, as consistency of processes across sites will increase efficiencies and enhance data quality. Methods Over the past few months the authors have been meeting to identify obstacles to multi-site chart abstraction and to address ways in which multi-site chart abstraction processes can be systemized and standardized. The aim of this workgroup is to create a best practice guide for multi-site chart abstraction studies. Focus areas include: abstractor training, format for chart abstraction (database, paper, etc), data quality, redaction, mechanism for transferring data, site specific access to medical records, IRB/HIPAA concerns, and budgetary issues. Results The results of the workgroup’s efforts (the best practice guide) will be presented by a panel of experts at the 2012 HMORN conference. The presentation format will also focus on discussion among attendees to elicit further input and to identify areas that need to be further addressed. Subsequently, the best practice guide will be posted on the HMORN website. Discussion The best practice guide for multi-site chart abstraction studies will establish sound guidelines and serve as an aid to researchers embarking on multi-site chart abstraction studies. Efficiencies and data quality will be further enhanced with standardized multi-site chart abstraction practices.

  5. Abstract analogical reasoning in high-functioning children with autism spectrum disorders.

    PubMed

    Green, Adam E; Kenworthy, Lauren; Mosner, Maya G; Gallagher, Natalie M; Fearon, Edward W; Balhana, Carlos D; Yerys, Benjamin E

    2014-12-01

    Children with autism spectrum disorders (ASD) exhibit a deficit in spontaneously recognizing abstract similarities that are crucial for generalizing learning to new situations. This may contribute to deficits in the development of appropriate schemas for navigating novel situations, including social interactions. Analogical reasoning is the central cognitive mechanism that enables typically developing children to understand abstract similarities between different situations. Intriguingly, studies of high-functioning children with ASD point to a relative cognitive strength in basic, nonabstract forms of analogical reasoning. If this analogical reasoning ability extends to abstract analogical reasoning (i.e., between superficially dissimilar situations), it may provide a bridge between a cognitive capability and core ASD deficits in areas such as generalization and categorization. This study tested whether preserved analogical reasoning abilities in ASD can be extended to abstract analogical reasoning, using photographs of real-world items and situations. Abstractness of the analogies was determined via a quantitative measure of semantic distance derived from latent semantic analysis. Children with ASD performed as well as typically developing children at identifying abstract analogical similarities when explicitly instructed to apply analogical reasoning. Individual differences in abstract analogical reasoning ability predicted individual differences in a measure of social function in the ASD group. Preliminary analyses indicated that children with ASD, but not typically developing children, showed an effect of age on abstract analogical reasoning. These results provide new evidence that children with ASD are capable of identifying abstract similarities through analogical reasoning, pointing to abstract analogical reasoning as a potential lever for improving generalization skills and social function in ASD.

  6. Openness initiative

    SciTech Connect

    Duncan, S.S.

    1995-12-31

    Although antinuclear campaigns seem to be effective, public communication and education efforts on low-level radioactive waste have mixed results. Attempts at public information programs on low-level radioactive waste still focus on influencing public opinion. A question then is: {open_quotes}Is it preferable to have a program focus on public education that will empower individuals to make informed decisions rather than trying to influence them in their decisions?{close_quotes} To address this question, a case study with both quantitative and qualitative data will be used. The Ohio Low-Level Radioactive Waste Education Program has a goal to provide people with information they want/need to make their own decisions. The program initiated its efforts by conducting a statewide survey to determine information needed by people and where they turned for that information. This presentation reports data from the survey and then explores the program development process in which programs were designed and presented using the information. Pre and post data from the programs reveal attitude and knowledge shifts.

  7. Reporting quality of abstracts of trials published in top five pain journals: a protocol for a systematic survey

    PubMed Central

    Sriganesh, Kamath; Bharadwaj, Suparna; Wang, Mei; Abbade, Luciana P F; Couban, Rachel; Mbuagbaw, Lawrence; Thabane, Lehana

    2016-01-01

    Introduction Abstracts of randomised controlled trials (RCTs) are often the first and the only source read in a journal by busy healthcare providers. This necessitates good reporting of abstracts. The quality of reporting of abstracts, though gradually improving over time, is still not uniform across medical journals. Improvement in completeness of reporting of abstracts has been documented in general medical journals after the publication of the consolidated standards of reporting trials (CONSORT) extension for abstracts in 2008. Currently, this aspect has not been assessed with regards to pain journals. This study aims to compare the completeness of reporting of abstracts before and after the publication of CONSORT statement for abstracts in five pain journals. Methods and analyses The abstracts of RCTs published from 1 January 2005 to 31 December 2007 (pre-CONSORT) and from 1 January 2013 to 31 December 2015 (post-CONSORT) will be assessed for the quality of reporting. Studies without abstracts, non-English abstracts, abstracts not reporting on RCTs or on humans and conference abstracts will be excluded. A thorough search of MEDLINE will be carried out in April 2016. All identified studies will be screened for inclusion based on titles and abstracts. Data will be extracted by two sets of independent reviewers for each abstract in duplicate regarding compliance with CONSORT statement for abstracts. Full-text review will be performed to obtain additional characteristics which are likely to affect reporting quality. The unadjusted and adjusted differences in the mean number of items reported will be analysed using a two sample t-test and generalised estimation equation in SPSS. Ethics and dissemination As far as we know, this is the first study to evaluate reporting quality of abstracts of pain journals based on CONSORT extension for abstracts. The findings of this study will be disseminated by a presentation at a conference and through publication in a peer

  8. Differences between ADEA Annual Session poster abstracts and their corresponding full published articles.

    PubMed

    Yuan, Judy Chia-Chun; Galang, Maria Therese S; Lee, Damian J; Barao, Valentim A R; Shyamsunder, Nodesh; Sukotjo, Cortino

    2011-11-01

    The purpose of this study was to investigate differences between abstracts of posters presented at the 79(th) (2002) and 80(th) (2003) Annual Session & Exhibition of the American Dental Education Association (ADEA) and the published full-length articles resulting from the same studies. The abstracts for poster presentation sessions were downloaded, and basic characteristics of the abstracts and their authors were determined. A PubMed search was then performed to identify the publication of full-length articles based on those abstracts in a peer-reviewed journal. The differences between the abstract and the article were examined and categorized as major and minor differences. Differences identified included authorship, title, materials and methods, results, conclusions, and funding. Data were analyzed with both descriptive and analytic statistics. Overall, 89 percent of the abstracts had at least one variation from its corresponding article, and 65 percent and 76 percent of the abstracts had at least one major and minor variation, respectively, from its corresponding article. The most prevalent major variation was in study results, and the most prevalent minor variation was change in the number of authors. The discussion speculates on some possible reasons for these differences.

  9. Supramodal neural processing of abstract information conveyed by speech and gesture

    PubMed Central

    Straube, Benjamin; He, Yifei; Steines, Miriam; Gebhardt, Helge; Kircher, Tilo; Sammer, Gebhard; Nagels, Arne

    2013-01-01

    Abstractness and modality of interpersonal communication have a considerable impact on comprehension. They are relevant for determining thoughts and constituting internal models of the environment. Whereas concrete object-related information can be represented in mind irrespective of language, abstract concepts require a representation in speech. Consequently, modality-independent processing of abstract information can be expected. Here we investigated the neural correlates of abstractness (abstract vs. concrete) and modality (speech vs. gestures), to identify an abstractness-specific supramodal neural network. During fMRI data acquisition 20 participants were presented with videos of an actor either speaking sentences with an abstract-social [AS] or concrete-object-related content [CS], or performing meaningful abstract-social emblematic [AG] or concrete-object-related tool-use gestures [CG]. Gestures were accompanied by a foreign language to increase the comparability between conditions and to frame the communication context of the gesture videos. Participants performed a content judgment task referring to the person vs. object-relatedness of the utterances. The behavioral data suggest a comparable comprehension of contents communicated by speech or gesture. Furthermore, we found common neural processing for abstract information independent of modality (AS > CS ∩ AG > CG) in a left hemispheric network including the left inferior frontal gyrus (IFG), temporal pole, and medial frontal cortex. Modality specific activations were found in bilateral occipital, parietal, and temporal as well as right inferior frontal brain regions for gesture (G > S) and in left anterior temporal regions and the left angular gyrus for the processing of speech semantics (S > G). These data support the idea that abstract concepts are represented in a supramodal manner. Consequently, gestures referring to abstract concepts are processed in a predominantly left hemispheric language

  10. NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 06)

    NASA Technical Reports Server (NTRS)

    1975-01-01

    Patents and applications for patent introduced into the NASA scientific and technical information system are cited. Each entry consists of a citation, an abstract, and a key illustration selected from the patent or application for patent. The patent and application for patent citations are indexed according to subject, inventor, source, number, and accession number.

  11. Strengthening Structured Abstracts for Education Research: The Need for Claim-Based Structured Abstracts

    ERIC Educational Resources Information Center

    Kelly, Anthony E.; Yin, Robert K.

    2007-01-01

    Recent policy recommendations involving the putative primacy of randomized clinical trials in educational settings have reignited research paradigm debates. The authors of this article use the vehicle of strengthening structured journal abstracts to point out the argumentative character of all education research claims. They offer suggestions to…

  12. Business and Organizational Communication: Abstracts of Doctoral Dissertations Published in "Dissertation Abstracts International," January through June 1981 (Vol. 41 Nos. 7 through 12).

    ERIC Educational Resources Information Center

    ERIC Clearinghouse on Reading and Communication Skills, Urbana, IL.

    This collection of abstracts is part of a continuing series providing information on recent doctoral dissertations. The 12 titles deal with the following topics: (1) identifying problem formation behaviors within the process of organizational change; (2) using the communication audit to determine decision style, satisfaction, and communication…

  13. The Primacy of Abstract Syllables in Chinese Word Production

    PubMed Central

    Chen, Jenn-Yeu; O’Séaghdha, Pádraig G.; Chen, Train-Min

    2015-01-01

    Convergent evidence suggests that syllables play a primary and distinctive role in the phonological phase of Mandarin Chinese word production. Specifically, syllables are selected before other phonological components and thus guide subsyllabic encoding. The proximity of phonological syllables to word representations in Chinese languages ensures that they are also activated automatically by word perception. Therefore, in contrast to Indo-European languages, syllables but not necessarily subsyllabic components such as initial consonants can be perceptually primed in production. We tested this prediction in two masked-priming experiments. To isolate relevant phonological activation originating in primes, we used single character masked primes whose corresponding tones and lexical meanings always differed from those of the targets’ first morphemes. Related primes potentially activated the atonal first syllables or the first consonants of target words. To strongly engage production-specific processes, we used pictures as prompts for disyllabic target words. Facilitation relative to unrelated controls was observed only in the syllable sharing condition. If anything, sharing of initial consonants had a negative valence, perhaps indicative of competition among similar co-activated words or syllables. These findings corroborate the view that abstract syllables are the first selected, proximate phonological units in Chinese word production, and that phonemic segments play a subordinate role. PMID:26618911

  14. Metaphors are physical and abstract: ERPs to metaphorically modified nouns resemble ERPs to abstract language

    PubMed Central

    Forgács, Bálint; Bardolph, Megan D.; Amsel, Ben D.; DeLong, Katherine A.; Kutas, Marta

    2015-01-01

    Metaphorical expressions very often involve words referring to physical entities and experiences. Yet, figures of speech such as metaphors are not intended to be understood literally, word-by-word. We used event-related brain potentials (ERPs) to determine whether metaphorical expressions are processed more like physical or more like abstract expressions. To this end, novel adjective-noun word pairs were presented visually in three conditions: (1) Physical, easy to experience with the senses (e.g., “printed schedule”); (2) Abstract, difficult to experience with the senses (e.g., “conditional schedule”); and (3) novel Metaphorical, expressions with a physical adjective, but a figurative meaning (e.g., “thin schedule”). We replicated the N400 lexical concreteness effect for concrete vs. abstract adjectives. In order to increase the sensitivity of the concreteness manipulation on the expressions, we divided each condition into high and low groups according to rated concreteness. Mirroring the adjective result, we observed a N400 concreteness effect at the noun for physical expressions with high concreteness ratings vs. abstract expressions with low concreteness ratings, even though the nouns per se did not differ in lexical concreteness. Paradoxically, the N400 to nouns in the metaphorical expressions was indistinguishable from that to nouns in the literal abstract expressions, but only for the more concrete subgroup of metaphors; the N400 to the less concrete subgroup of metaphors patterned with that to nouns in the literal concrete expressions. In sum, we not only find evidence for conceptual concreteness separable from lexical concreteness but also that the processing of metaphorical expressions is not driven strictly by either lexical or conceptual concreteness. PMID:25713520

  15. In defense of abstract conceptual representations.

    PubMed

    Binder, Jeffrey R

    2016-08-01

    An extensive program of research in the past 2 decades has focused on the role of modal sensory, motor, and affective brain systems in storing and retrieving concept knowledge. This focus has led in some circles to an underestimation of the need for more abstract, supramodal conceptual representations in semantic cognition. Evidence for supramodal processing comes from neuroimaging work documenting a large, well-defined cortical network that responds to meaningful stimuli regardless of modal content. The nodes in this network correspond to high-level "convergence zones" that receive broadly crossmodal input and presumably process crossmodal conjunctions. It is proposed that highly conjunctive representations are needed for several critical functions, including capturing conceptual similarity structure, enabling thematic associative relationships independent of conceptual similarity, and providing efficient "chunking" of concept representations for a range of higher order tasks that require concepts to be configured as situations. These hypothesized functions account for a wide range of neuroimaging results showing modulation of the supramodal convergence zone network by associative strength, lexicality, familiarity, imageability, frequency, and semantic compositionality. The evidence supports a hierarchical model of knowledge representation in which modal systems provide a mechanism for concept acquisition and serve to ground individual concepts in external reality, whereas broadly conjunctive, supramodal representations play an equally important role in concept association and situation knowledge.

  16. DOE NABIR PI Workshop: Abstracts 2002

    SciTech Connect

    Hawkes , Dan

    2002-01-09

    The mission of the NABIR program is to provide the fundamental science that will serve as the basis for the development of cost-effective bioremediation and long-term stewardship of radionuclides and metals in the subsurface at DOE sites. The focus of the program is on strategies leading to long-term immobilization of contaminants in place to reduce the risk to humans and the environment. Contaminants of special interest are uranium, technetium, plutonium, chromium, and mercury. The focus of the NABIR program is on the bioremediation of these contaminants in the subsurface below the root zone, including both vadose and saturated zones. The program is implemented through four interrelated scientific research elements (Biogeochemistry, Biomolecular Science and Engineering, Biotransformation, and Community Dynamics/Microbial Ecology); and through an element called Bioremediation and its Societal Implications and Concerns (BASIC), which addresses societal issues and potential concerns of stakeholders. The material presented at this year's workshop focuses on approximately 60 research projects funded in FY 2000-2002 by DOE's Office of Biological and Environmental Research (BER). Abstracts of NABIR research projects are provided in this book.

  17. Observational Activities at Manipur University, India (Abstract)

    NASA Astrophysics Data System (ADS)

    Singh, K. Y.; Meitei, I. A.; Singh, S. A.; Singh, R. B.

    2015-06-01

    (Abstract only) We have innovatively designed and constructed three observatories each costing a few hundred USD for housing three small Schmidt-Cassegrain type telescopes namely, Celestron CGE925, Celestron CGE1400, Meade 12-inch LX200GPS. These observatories are completely different in design and are found to be perfectly usable for doing serious work on astronomical observation and measurements. The observatory with the Celestron CGE1400 telescope has been inducted, since January 2012, as one of the observatories of the international “Orion Project” headquartered at Phoenix, Arizona, which is dedicated for photometric and spectroscopic observations of five bright variable stars of the Orion constellation namely, Betelgeuse (alpha Ori), Rigel (beta Ori), Mintaka (delta Ori), Alnilam (epsilon Ori) and Alnitak (zeta Ori). Using this observatory, we have been producing BVRI photometric data for the five stars of the Orion project. The other observatory with the Meade 12-inch LX200GPS telescope is being inducted into service for CCD photometric study of SU UMa stars in connection with implementation of a project funded by Indian Space Research Organization (ISRO). In the present paper, we would like to describe our self-built observatories, our observational facilities, the BVRI photometric data that we acquired for the Orion project, and our future plan for observation of variable stars of interest.

  18. Going Over to the Dark Side (Abstract)

    NASA Astrophysics Data System (ADS)

    Cowall, D.

    2015-06-01

    (Abstract only) This is the tale of my continuing journey transforming from a visual to a CCD photometrist. It is my hope that sharing my experiences will help and encourage others to consider taking the same path. It has been hard, but fun; a wonderful opportunity as a newly retired physician to expand my horizons. However, my brain did have to make the switch from Biology to Physics. The major barrier that concerned me was cost, but change itself was also a challenge. Other issues included dealing with the complexity of technical systems and a myriad of details. My solution was to be patient and think small to insure success and then build upon all those little victories. The pedagogical component of this project was critical as well. It began with a good mentor and continued via networking with other members at meetings, taking CHOICE courses, and most importantly: practice, practice, practice. Each plateau suggested many new possibilities. I think “The Force” is now with me! The adventure continues.

  19. DOE-NABIR PI Workshop: Abstracts 2003

    SciTech Connect

    Various

    2003-01-28

    The mission of the NABIR program is to provide the fundamental science that will serve as the basis for the development of cost-effective bioremediation and long-term stewardship of radionuclides and metals in the subsurface at DOE sites. The focus of the program is on strategies leading to long-term immobilization of contaminants in situ to reduce the risk to humans and the environment. Contaminants of special interest are uranium, technetium, plutonium, chromium, and mercury. The focus of the NABIR program is on the bioremediation of these contaminants in the subsurface below the root zone, including both vadose and saturated zones. The program consists of four interrelated Science Elements (Biotransformation, Community Dynamics/Microbial Ecology, Biomolecular Science and Engineering, and Biogeochemistry). The program also has a cross-cutting Assessment Element that supports development of innovative approaches and technologies to support the science elements. An element called Bioremediation and its Societal Implications and Concerns (BASIC) addresses potential societal issues of implementing NABIR scientific findings. The material presented at this year's workshop focuses on approximately 60 research projects funded in FY 2000-2003 by the Environmental Remediation Sciences Division in DOE's Office of Biological and Environmental Research (BER) in the Office of Science. Abstracts of NABIR research projects are provided in this book.

  20. Completeness of reporting in abstracts from clinical trials of pre-harvest interventions against foodborne pathogens.

    PubMed

    Snedeker, Kate G; Canning, Paisley; Totton, Sarah C; Sargeant, Jan M

    2012-04-01

    Abstracts are the most commonly read part of a journal article, and play an important role as summaries of the articles, and search and screening tools. However, research on abstracts in human biomedicine has shown that abstracts often do not report key methodological features and results. Little research has been done to examine reporting of such features in abstracts from papers detailing pre-harvest food safety trials. Thus, the objective of this study was to assess the quality of reporting of key factors in abstracts detailing trials of pre-harvest food safety interventions. A systematic search algorithm was used to identify all in vivo trials of pre-harvest interventions against foodborne pathogens in PubMed and CAB Direct published from 1999 to October 2009. References were screened for relevance, and 150 were randomly chosen for inclusion in the study. A checklist based on the CONSORT abstract extension and the REFLECT Statement was used to assess the reporting of methodological features and results. All screening and assessment was performed by two independent reviewers with disagreements resolved by consensus. The systematic search returned 3554 unique citations; 356 were found to be relevant and 150 were randomly selected for inclusion. The abstracts were from 51 different journals, and 13 out of 150 were structured. Of the 124 abstracts that reported whether the trial design was deliberate disease challenge or natural exposure, 113 were deliberate challenge and 11 natural exposure. 103 abstracts detailed studies involving poultry, 20 cattle and 15 swine. Most abstracts reported the production stage of the animals (135/150), a hypothesis or objective (123/150), and results for all treatment groups (136/150). However, few abstracts reported on how animals were grouped in housing (25/150), the location of the study (5/150), the primary outcome (2/126), level of treatment allocation (15/150), sample size (63/150) or whether study units were lost to follow up

  1. Book of Abstracts from the MORS Symposium (62nd) Held in Colorado Springs, Colorado

    DTIC Science & Technology

    1994-06-01

    Abstract not available. Pre-Test Modeling of the Javelin Antitank System Al Heston Sverdrup Technology The Army conducted an Initial Test and...30 user accounts which often and include 6-8 scenarios running simultaneously. We have 2LTs Jeff Leischner, Jennifer Henderson, and John developed an...19 Helmuth, Richard .................... 1,2 Flickinger, William H .................... 90 Henderson, Jennifer .................... 106

  2. Role of point defects/defect complexes in silicon device processing. Book of abstracts, fourth workshop

    SciTech Connect

    Not Available

    1994-06-01

    The 41 abstracts are arranged into 6 sessions: impurities and defects in commercial substrates: their sources, effects on material yield, and material quality; impurity gettering in silicon: limits and manufacturability of impurity gettering and in silicon solar cells; impurity/defect passivation; new concepts in silicon growth: improved initial quality and thin films; and silicon solar cell design opportunities.

  3. Thirty-seventh ORNL/DOE conference on analytical chemistry in energy technology: Abstracts of papers

    SciTech Connect

    1997-12-31

    Abstracts only are given for papers presented during the following topical sessions: Opportunities for collaboration: Industry, academic, national laboratories; Developments in sensor technology; Analysis in containment facilities; Improving the quality of environmental data; Process analysis; Field analysis; Radiological separations; Interactive analytical seminars; Measurements and chemical industry initiatives; and Isotopic measurements and mass spectroscopy.

  4. A Neural Region of Abstract Working Memory

    ERIC Educational Resources Information Center

    Cowan, Nelson; Li, Dawei; Moffitt, Amanda; Becker, Theresa M.; Martin, Elizabeth A.; Saults, J. Scott; Christ, Shawn E.

    2011-01-01

    Over 350 years ago, Descartes proposed that the neural basis of consciousness must be a brain region in which sensory inputs are combined. Using fMRI, we identified at least one such area for working memory, the limited information held in mind, described by William James as the trailing edge of consciousness. Specifically, a region in the left…

  5. Space Electrochemical Research and Technology Conference: Abstracts

    NASA Technical Reports Server (NTRS)

    1989-01-01

    The objectives of the conference were to examine current technologies, research efforts, and advanced ideas, and to identify technical barriers which affect the advancement of electrochemical energy storage systems for space applications. Papers were presented and workshops were conducted in four technical areas: advanced concepts, hydrogen-oxygen fuel cells and electrolyzers, the nickel electrode, and advanced rechargeable batteries.

  6. An In-Situ Grazing Incidence X-Ray Scattering Study of the Initial Stages of Electrochemical Growth of Lead on Silver (3)

    DTIC Science & Technology

    1988-11-05

    necessary ad Identify by block nulnber) N The potential dependent structure of underpotentially deposited lead on silver(III) and the initial stages of bulk...The closed packed triangular lattice of lead formed by the underpotential deposition (.at full monolayer coverage) is compressed 1.4% relative to...00931 ABSTRACT The potential dependent structure of underpotentially deposited lead on silver (111) and the initial stages of bulk lead deposition on the

  7. Automatic Review of Abstract State Machines by Meta Property Verification

    NASA Technical Reports Server (NTRS)

    Arcaini, Paolo; Gargantini, Angelo; Riccobene, Elvinia

    2010-01-01

    A model review is a validation technique aimed at determining if a model is of sufficient quality and allows defects to be identified early in the system development, reducing the cost of fixing them. In this paper we propose a technique to perform automatic review of Abstract State Machine (ASM) formal specifications. We first detect a family of typical vulnerabilities and defects a developer can introduce during the modeling activity using the ASMs and we express such faults as the violation of meta-properties that guarantee certain quality attributes of the specification. These meta-properties are then mapped to temporal logic formulas and model checked for their violation. As a proof of concept, we also report the result of applying this ASM review process to several specifications.

  8. Identifying Codes on Directed De Bruijn Graphs

    DTIC Science & Technology

    2015-08-27

    JOURNAL ARTICLE (POST PRINT) 3. DATES COVERED (From - To) JUN 2013 – AUG 2015 4. TITLE AND SUBTITLE IDENTIFYING CODES ON DIRECTED DE BRUIJN GRAPHS 5a...owner. 14. ABSTRACT For a directed graph G, a t-identifying code is a subset S ⊆ V (G) with the property that for each vertex v ∈ V (G) the set of...t-identifying code . This paper shows that the directed de Bruijn graph B(d, n) is t- identifiable for n ≥ 2t−1, and is not t-identifiable for n ≤ 2t

  9. IM Normae: A Second T Pyx? (Abstract)

    NASA Astrophysics Data System (ADS)

    Patterson, J.; Monard, B.; Warhurst, P.; Myers, G.

    2015-12-01

    (Abstract only) T Pyx is the Galaxy's most famous recurrent nova, erupting to magnitude 6 about every 20 years. For nova hunters and variable-star observers generally, it should be quite easy to discover stars with similar properties. There are probably half a million CVs out to the distance of T Pyx, and most have an underlying structure similar to that of T Pyx: low-mass secondary, fairly massive white dwarf, short orbital period. But of these half million stars, there is no second T Pyx. The star is unique in another way: its orbital period is increasing on a timescale of 300,000 years. Like the proverbial bat out of hell. A 2002 nova eruption nominated a second star for this elite club: IM Nor, a short-orbital-period (2.5 hours) star which previously erupted in 1920. We began a program of time-series photometry to track the shallow eclipses—to test for orbital period change, the other signature of T Pyx resemblance. By 2015 we found this effect: Porb increases on a timescale of 2 million years. Thus, the two stars appear to be blowing themselves apart on a timescale of roughly a million years. This could explain why the stars are so rare: because they are rapidly self-immolating. And that could happen because the classical-nova outburst overwhelms the low-mass secondaries that live in short-period CVs—leading to unstable mass transfer which quickly evaporates the secondary. This implies that all short-Porb classical novae should be "recurrent" (erupting on a timescale of decades). Greater attention to CP Pup (1942), RW UMi (1956), GQ Mus (1983), and V Per (1887) is definitely warranted.

  10. Abstracts of ARI Research Publications, FY 1976

    DTIC Science & Technology

    1979-11-01

    complementary characteris- tics . The PPS-5A radar detected and located targets well; the AN/TVS-4 Night Observation Device (NOD) was better in identifying...two-sided, free-play tactical training employing recognized principles of learning is achieved through simulated combat engagement situations. For...lessons learned . The method is enthusiastically accepted and the learning of appropri- ate behavior is rapid. REALTRAIN principles have also been

  11. Temporal and comparative outcomes of cardiac electrophysiology abstracts.

    PubMed

    Wong, Christopher X; Sun, Michelle T; Cheng, Yi Han; Dang, Jerry; Barlow, David S; Chia, Nicholas H; Wong, Nicole X; Wong, Michelle X; Lau, Dennis H; Brooks, Anthony G; Roberts-Thomson, Kurt C; Sanders, Prashanthan

    2013-07-15

    Although conferences are important vehicles for discussing scientific findings, the translation of presented research into peer-reviewed manuscripts is a crucial subsequent step in the research process. Given the evolving subspecialization of cardiology, we sought to characterize the temporal and comparative outcomes of abstracts presented at a subspecialty cardiac electrophysiology conference. Abstracts presented at the Heart Rhythm Society conference (1994 through 2006; HRS abstracts) and abstracts presented at the American Heart Association conference (2003; AHA abstracts) were studied. Subsequent publications, impact factors, and citation rates were determined. A total of 3,850 HRS and 1,000 AHA abstracts were studied. More human abstracts were presented at HRS than AHA (p <0.05). Compared with HRS abstracts, more AHA abstracts were published (p <0.001) and had higher impact factors and citation rates (p <0.001 for both). These differences were attributable in part to the greater proportion of human HRS abstracts. Compared with HRS abstracts, electrophysiology-related AHA abstracts were published less (p <0.001), and these publications had similar impact factors (p = 0.38) although greater citation rates (p = 0.001). The number and publication rate of HRS abstracts increased over the 15-year period, as did their publication impact factors and citation rates (p <0.001 for all). In conclusion, there are significant differences between AHA and HRS abstracts. Although AHA abstracts were more likely to be published overall, the publication rate and impact of electrophysiology abstracts presented at both a subspecialty (HRS) and a major cardiovascular conference (AHA) were comparable. There has also been a growth in the number and impact of cardiac electrophysiology abstracts presented at HRS in recent years.

  12. Teaching the Abstract as an Introduction to Technical Writing.

    ERIC Educational Resources Information Center

    Mendelson, Michael

    1987-01-01

    Suggests using abstract writing to introduce students to various elements of technical writing such as organization, stylistic choice, and revision. Provides examples of students' condensations and summarizes the benefits of teaching abstract writing. (SRT)

  13. A Review of Errors in the Journal Abstract

    ERIC Educational Resources Information Center

    Lee, Eunpyo; Kim, Eun-Kyung

    2013-01-01

    (percentage) of abstracts that involved with errors, the most erroneous part of the abstract, and the types and frequency of errors. Also the purpose expanded to compare the results with those of the previous…

  14. Introducing structured abstracts for A&A articles

    NASA Astrophysics Data System (ADS)

    Bertout, Claude; Schneider, Peter

    2005-10-01

    Context: Due to their wide availability, abstracts have become the most important part of any astrophysical paper. Aims: Having noticed that abstracts published in astronomical journals are not always optimal, we introduce the concept of structured abstracts for A&A articles. Methods: We explain what structured abstracts are and where they come from, provide examples showing how to structure an abstract, and discuss the advantages and drawbacks of this novel concept. In an on-line appendix, we show what some published abstracts look like once they are structured. Results: We demonstrate the improvements in information content, readability, and style that can be made when writing structured abstracts instead of traditional ones. Conclusions: A new version 6.0 of the A&A LaTeX macro is now available for structuring the abstracts of articles, and A&A authors are kindly invited to use it for their new submissions.

  15. Clad Degradation- Summary and Abstraction for LA

    SciTech Connect

    D. Stahl

    2004-10-01

    The purpose of this model report is to develop the summary cladding degradation abstraction that will be used in the Total System Performance Assessment for the License Application (TSPA-LA). Most civilian commercial nuclear fuel is encased in Zircaloy cladding. The model addressed in this report is intended to describe the postulated condition of commercial Zircaloy-clad fuel as a function of postclosure time after it is placed in the repository. Earlier total system performance assessments analyzed the waste form as exposed UO{sub 2}, which was available for degradation at the intrinsic dissolution rate. Water in the waste package quickly became saturated with many of the radionuclides, limiting their release rate. In the total system performance assessments for the Viability Assessment and the Site Recommendation, cladding was analyzed as part of the waste form, limiting the amount of fuel available at any time for degradation. The current model is divided into two stages. The first considers predisposal rod failures (most of which occur during reactor operation and associated activities) and postdisposal mechanical failure (from static loading of rocks) as mechanisms for perforating the cladding. Other fuel failure mechanisms including those caused by handling or transportation have been screened out (excluded) or are treated elsewhere. All stainless-steel-clad fuel, which makes up a small percentage of the overall amount of fuel to be stored, is modeled as failed upon placement in the waste packages. The second stage of the degradation model is the splitting of the cladding from the reaction of water or moist air and UO{sub 2}. The splitting has been observed to be rapid in comparison to the total system performance assessment time steps and is modeled to be instantaneous. After the cladding splits, the rind buildup inside the cladding widens the split, increasing the diffusion area from the fuel rind to the waste package interior. This model report summarizes

  16. Localization Versus Abstraction: A Comparison of Two Search Reduction Techniques

    NASA Technical Reports Server (NTRS)

    Lansky, Amy L.

    1992-01-01

    There has been much recent work on the use of abstraction to improve planning behavior and cost. Another technique for dealing with the inherently explosive cost of planning is localization. This paper compares the relative strengths of localization and abstraction in reducing planning search cost. In particular, localization is shown to subsume abstraction. Localization techniques can model the various methods of abstraction that have been used, but also provide a much more flexible framework, with a broader range of benefits.

  17. GOClonto: an ontological clustering approach for conceptualizing PubMed abstracts.

    PubMed

    Zheng, Hai-Tao; Borchert, Charles; Kim, Hong-Gee

    2010-02-01

    Concurrent with progress in biomedical sciences, an overwhelming of textual knowledge is accumulating in the biomedical literature. PubMed is the most comprehensive database collecting and managing biomedical literature. To help researchers easily understand collections of PubMed abstracts, numerous clustering methods have been proposed to group similar abstracts based on their shared features. However, most of these methods do not explore the semantic relationships among groupings of documents, which could help better illuminate the groupings of PubMed abstracts. To address this issue, we proposed an ontological clustering method called GOClonto for conceptualizing PubMed abstracts. GOClonto uses latent semantic analysis (LSA) and gene ontology (GO) to identify key gene-related concepts and their relationships as well as allocate PubMed abstracts based on these key gene-related concepts. Based on two PubMed abstract collections, the experimental results show that GOClonto is able to identify key gene-related concepts and outperforms the STC (suffix tree clustering) algorithm, the Lingo algorithm, the Fuzzy Ants algorithm, and the clustering based TRS (tolerance rough set) algorithm. Moreover, the two ontologies generated by GOClonto show significant informative conceptual structures.

  18. Abstractions for Fault-Tolerant Distributed System Verification

    NASA Technical Reports Server (NTRS)

    Pike, Lee S.; Maddalon, Jeffrey M.; Miner, Paul S.; Geser, Alfons

    2004-01-01

    Four kinds of abstraction for the design and analysis of fault tolerant distributed systems are discussed. These abstractions concern system messages, faults, fault masking voting, and communication. The abstractions are formalized in higher order logic, and are intended to facilitate specifying and verifying such systems in higher order theorem provers.

  19. Diagrams of stability of circumbinary planetary systems (Abstract)

    NASA Astrophysics Data System (ADS)

    Popova, E.

    2015-08-01

    The stability diagrams in the "pericentric distance - eccentricity" plane of initial data are built and analysed for Kepler-38, Kepler-47, and PH1. This completes a survey of stability of the known up to now circumbinary planetary systems, initiated by Popova and Shevchenko (ApJ, 769, 152, 2013), where the analysis was performed for Kepler-16, 34, and 35. In the diagrams, the planets appear to be "embedded" in the fractal chaos border; however, I make an attempt to measure the "distance" to the chaos border in a physically consistent way. The obtained distances are compared to those given by the widely used numerical-experimental criterion by Holman and Wiegert (1999), who employed smooth polynomial approximations to describe the border. I identify the resonance cells, hosting the planets. Results of this study will appear in Proceedings of IAU Symposium 310 "Complex planetary systems".

  20. A temporal-abstraction system for patient monitoring.

    PubMed Central

    Shahar, Y.; Musen, M. A.

    1992-01-01

    RESUME is a system that performs temporal abstraction of time-stamped data. RESUME is based on a model of three temporal-abstraction mechanisms: point temporal abstraction (a mechanism for abstracting values of several parameters into a value of another parameter); temporal inference (a mechanism for inferring sound logical conclusions over a single interval or two meeting intervals); and temporal interpolation (a mechanism for bridging nonmeeting temporal intervals). Making explicit the knowledge required for temporal abstraction supports the acquisition of that knowledge. PMID:1482852

  1. The North American Amphibian Monitoring Program. [abstract

    USGS Publications Warehouse

    Griffin, J.

    1998-01-01

    The North American Amphibian Monitoring Program has been under development for the past three years. The monitoring strategy for NAAMP has five main prongs: terrestrial salamander surveys, calling surveys, aquatic surveys, western surveys, and atlassing. Of these five, calling surveys were selected as one of the first implementation priorities due to their friendliness to volunteers of varying knowledge levels, relative low cost, and the fact that several groups had already pioneered the techniques involved. While some states and provinces had implemented calling surveys prior to NAAMP, like WI and IL, most states and provinces had little or no history of state/provincewide amphibian monitoring. Thus, the majority of calling survey programs were initiated in the past two years. To assess the progress of this pilot phase, a program review was conducted on the status of the NAAMP calling survey program, and the results of that review will be presented at the meeting. Topics to be discussed include: who is doing what where, extent of route coverage, the continuing random route discussions, quality assurance, strengths and weaknesses of calling surveys, reliability of data, and directions for the future. In addition, a brief overview of the DISPro project will be included. DISPro is a new amphibian monitoring program in National Parks, funded by the Demonstration of Intensive Sites Program (DISPro) through the EPA and NPS. It will begin this year at Big Bend and Shenandoah National Parks. The purpose of the DISPro Amphibian Project will be to investigate relationships between environmental factors and stressors and the distribution, abundance, and health of amphibians in these National Parks. At each Park, amphibian long-term monitoring protocols will be tested, distributions and abundance of amphibians will be mapped, and field research experiments will be conducted to examine stressor effects on amphibians (e.g., ultraviolet radiation, contaminants, acidification).

  2. CSNF WASTE FORM DEGRADATION: SUMMARY ABSTRACTION

    SciTech Connect

    J.C. CUNNANE

    2004-08-31

    The purpose of this model report is to describe the development and validation of models that can be used to calculate the release of radionuclides from commercial spent nuclear fuel (CSNF) following a hypothetical breach of the waste package and fuel cladding in the repository. The purpose also includes describing the uncertainties associated with modeling the radionuclide release for the range of CSNF types, exposure conditions, and durations for which the radionuclide release models are to be applied. This document was developed in accordance with Technical Work Plan for: Regulatory Integration Modeling and Analysis of the Waste Form and Waste Package (BSC 2004 [DIRS 169944]). This document considers radionuclides to be released from CSNF when they are available for mobilization by gas-phase mass transport, or by dissolution or colloid formation in water that may contact the fuel. Because other reports address limitations on the dissolved and colloidal radionuclide concentrations (BSC 2004 [DIRS 169944], Table 2-1), this report does not address processes that control the extent to which the radionuclides released from CSNF are mobilized and transported away from the fuel either in the gas phase or in the aqueous phase as dissolved and colloidal species. The scope is limited to consideration of degradation of the CSNF rods following an initial breach of the cladding. It considers features of CSNF that limit the availability of individual radionuclides for release into the gaseous or aqueous phases that may contact the fuel and the processes and events expected to degrade these CSNF features. In short, the purpose is to describe the characteristics of breached fuel rods and the degradation processes expected to influence radionuclide release.

  3. A grounded theory of abstraction in artificial intelligence.

    PubMed

    Zucker, Jean-Daniel

    2003-07-29

    In artificial intelligence, abstraction is commonly used to account for the use of various levels of details in a given representation language or the ability to change from one level to another while preserving useful properties. Abstraction has been mainly studied in problem solving, theorem proving, knowledge representation (in particular for spatial and temporal reasoning) and machine learning. In such contexts, abstraction is defined as a mapping between formalisms that reduces the computational complexity of the task at stake. By analysing the notion of abstraction from an information quantity point of view, we pinpoint the differences and the complementary role of reformulation and abstraction in any representation change. We contribute to extending the existing semantic theories of abstraction to be grounded on perception, where the notion of information quantity is easier to characterize formally. In the author's view, abstraction is best represented using abstraction operators, as they provide semantics for classifying different abstractions and support the automation of representation changes. The usefulness of a grounded theory of abstraction in the cartography domain is illustrated. Finally, the importance of explicitly representing abstraction for designing more autonomous and adaptive systems is discussed.

  4. A grounded theory of abstraction in artificial intelligence.

    PubMed Central

    Zucker, Jean-Daniel

    2003-01-01

    In artificial intelligence, abstraction is commonly used to account for the use of various levels of details in a given representation language or the ability to change from one level to another while preserving useful properties. Abstraction has been mainly studied in problem solving, theorem proving, knowledge representation (in particular for spatial and temporal reasoning) and machine learning. In such contexts, abstraction is defined as a mapping between formalisms that reduces the computational complexity of the task at stake. By analysing the notion of abstraction from an information quantity point of view, we pinpoint the differences and the complementary role of reformulation and abstraction in any representation change. We contribute to extending the existing semantic theories of abstraction to be grounded on perception, where the notion of information quantity is easier to characterize formally. In the author's view, abstraction is best represented using abstraction operators, as they provide semantics for classifying different abstractions and support the automation of representation changes. The usefulness of a grounded theory of abstraction in the cartography domain is illustrated. Finally, the importance of explicitly representing abstraction for designing more autonomous and adaptive systems is discussed. PMID:12903672

  5. Content and accuracy of abstracting services: clinical perspective.

    PubMed

    Michel, D J

    1988-07-01

    Abstracts in Inpharma, deHaen Drugs-in-Use, International Pharmaceutical Abstracts (IPA), Reactions, and Clin-Alert were evaluated using the number of omissions and errors as endpoints. Fifty-one abstracts were compared with original articles by pharmacy students using a standardized checklist for drug therapy and adverse drug reaction articles. The overall omission rate per abstract was 3.2 +/- 2.5. There were no significant differences in omission rates in drug therapy abstracts between Inpharma, deHaen, or IPA abstracting services. For adverse drug reaction abstracts, IPA had significantly more omissions than Clin-Alert (p less than 0.001) and Reactions (p less than 0.01). One error occurred in approximately every fifth abstract. No differences were shown between abstracting services in this regard. Although abstracts and abstracting services can provide useful information--particularly when information is needed in a timely fashion, when an original article is difficult to obtain, or when written in a foreign language--they should not be considered a consistently reliable source of information upon which to base decisions, as evidenced by the number and types of omissions and errors described in this study.

  6. DNA damage by the sulfate radical anion: hydrogen abstraction from the sugar moiety versus one-electron oxidation of guanine.

    PubMed

    Roginskaya, Marina; Mohseni, Reza; Ampadu-Boateng, Derrick; Razskazovskiy, Yuriy

    2016-07-01

    The products of oxidative damage to double-stranded (ds) DNA initiated by photolytically generated sulfate radical anions SO4(•-) were analyzed using reverse-phase (RP) high-performance liquid chromatography (HPLC). Relative efficiencies of two major pathways were compared: production of 8-oxoguanine (8oxoG) and hydrogen abstraction from the DNA 2-deoxyribose moiety (dR) at C1,' C4,' and C5' positions. The formation of 8oxoG was found to account for 87% of all quantified lesions at low illumination doses. The concentration of 8oxoG quickly reaches a steady state at about one 8oxoG per 100 base pairs due to further oxidation of its products. It was found that another guanine oxidation product identified as 2-amino-5-(2'-alkylamino)-4H-imidazol-4-one (X) was released in significant quantities from its tentative precursor 2-amino-5-[(2'-deoxy-β-d-erythro-pentofuranosyl)amino]-4H-imidazol-4-one (dIz) upon treatment with primary amines in neutral solutions. The linear dose dependence of X release points to the formation of dIz directly from guanine and not through oxidation of 8oxoG. The damage to dR was found to account for about 13% of the total damage, with majority of lesions (33%) originating from the C4' oxidation. The contribution of C1' oxidation also turned out to be significant (17% of all dR damages) despite of the steric problems associated with the abstraction of the C1'-hydrogen. However, no evidence of base-to-sugar free valence transfer as a possible alternative to direct hydrogen abstraction at C1' was found.

  7. Abstracts of Phase 1 awards, (fiscal year) 1987

    SciTech Connect

    Not Available

    1987-01-01

    Contained in this booklet are abstracts of the Phase I awards made in Fiscal Year 1987 under the Small Business Innovation Research (SBIR) program in the Department of Energy (DOE). The program is designed for implementation in a three-phase process, with Phase I determining the scientific or technical merit and feasibility of ideas proposed for investigation. The period of performance in this initial phase is relatively brief, typically about 6 months, and the awards are limited to $50,000. Phase II is the principal research or research and development effort, and the awards are as high as $500,000 for work to be performed in periods of up to 2 years. Phase III is the commercial application. The 111 Phase I projects described were selected in a highly competitive process from a total of 942 proposals received in response to the 1987 Solicitation. They cover the fields of chemistry, materials, control systems, plant natural products, instrumentation, nuclear medicine, health and environmental effects, high energy physics, particle accelerators, nuclear physics, plasma diagnostics and confinement, fusion energy systems, robotics and remote systems, nuclear reactors, space nuclear power, fuel cycle, decontamination/decommissioning, commputers in nuclear plants, coal, enhanced oil recovery/tar sands, fossil energy, photovoltaics, solar thermal, ceramics for heat engines, and industrial separation, conversion and recovery processes. (DLC)

  8. Structured hints : extracting and abstracting domain expertise.

    SciTech Connect

    Hereld, M.; Stevens, R.; Sterling, T.; Gao, G. R.; Mathematics and Computer Science; California Inst. of Tech.; Louisiana State Univ.; Univ. of Delaware

    2009-03-16

    We propose a new framework for providing information to help optimize domain-specific application codes. Its design addresses problems that derive from the widening gap between the domain problem statement by domain experts and the architectural details of new and future high-end computing systems. The design is particularly well suited to program execution models that incorporate dynamic adaptive methodologies for live tuning of program performance and resource utilization. This new framework, which we call 'structured hints', couples a vocabulary of annotations to a suite of performance metrics. The immediate target is development of a process by which a domain expert describes characteristics of objects and methods in the application code that would not be readily apparent to the compiler; the domain expert provides further information about what quantities might provide the best indications of desirable effect; and the interactive preprocessor identifies potential opportunities for the domain expert to evaluate. Our development of these ideas is progressing in stages from case study, through manual implementation, to automatic or semi-automatic implementation. In this paper we discuss results from our case study, an examination of a large simulation of a neural network modeled after the neocortex.

  9. Adding Abstraction and Reuse to a Network Modelling Tool Using the Reuseware Composition Framework

    NASA Astrophysics Data System (ADS)

    Johannes, Jendrik; Fernández, Miguel A.

    Domain-specific modelling (DSM) environments enable experts in a certain domain to actively participate in model-driven development. Developing DSM environments need to be cost-efficient, since they are only used by a limited group of domain experts. Different model-driven technologies promise to allow this cost-efficient development. [1] presented experiences in developing a DSM environment for telecommunication network modelling. There, challenges were identified that need to be addressed by other new modelling technologies. In this paper, we now present the results of addressing one of theses challenges - abstraction and reuse support - with the Reuseware Composition Framework. We show how we identified the abstraction and reuse features required in the telecommunication DSM environment in a case study and extended the existing environment with these features using Reuseware. We discuss the advantages of using this technology and propose a process for further improving the abstraction and reuse capabilities of the DSM environment in the future.

  10. Advanced Monitoring systems initiative

    SciTech Connect

    R.J. Venedam; E.O. Hohman; C.F. Lohrstorfer; S.J. Weeks; J.B. Jones; W.J. Haas

    2004-09-30

    The Advanced Monitoring Systems Initiative (AMSI) actively searches for promising technologies and aggressively moves them from the research bench into DOE/NNSA end-user applications. There is a large unfulfilled need for an active element that reaches out to identify and recruit emerging sensor technologies into the test and evaluation function. Sensor research is ubiquitous, with the seeds of many novel concepts originating in the university systems, but at present these novel concepts do not move quickly and efficiently into real test environments. AMSI is a widely recognized, self-sustaining ''business'' accelerating the selection, development, testing, evaluation, and deployment of advanced monitoring systems and components.

  11. Moving beyond Solving for "x": Teaching Abstract Algebra in a Liberal Arts Mathematics Course

    ERIC Educational Resources Information Center

    Cook, John Paul

    2015-01-01

    This paper details an inquiry-based approach for teaching the basic notions of rings and fields to liberal arts mathematics students. The task sequence seeks to encourage students to identify and comprehend core concepts of introductory abstract algebra by thinking like mathematicians; that is, by investigating an open-ended mathematical context,…

  12. Decoding Concrete and Abstract Action Representations During Explicit and Implicit Conceptual Processing.

    PubMed

    Wurm, Moritz F; Ariani, Giacomo; Greenlee, Mark W; Lingnau, Angelika

    2016-08-01

    Action understanding requires a many-to-one mapping of perceived input onto abstract representations that generalize across concrete features. It is debated whether such abstract action concepts are encoded in ventral premotor cortex (PMv; motor hypothesis) or, alternatively, are represented in lateral occipitotemporal cortex (LOTC; cognitive hypothesis). We used fMRI-based multivoxel pattern analysis to decode observed actions at concrete and abstract, object-independent levels of representation. Participants observed videos of 2 actions involving 2 different objects, using either an explicit or implicit task with respect to conceptual action processing. We decoded concrete action representations by training and testing a classifier to discriminate between actions within each object category. To identify abstract action representations, we trained the classifier to discriminate actions in one object and tested the classifier on actions performed on the other object, and vice versa. Region-of-interest and searchlight analyses revealed decoding in LOTC at both concrete and abstract levels during both tasks, whereas decoding in PMv was restricted to the concrete level during the explicit task. In right inferior parietal cortex, decoding was significant for the abstract level during the explicit task. Our findings are incompatible with the motor hypothesis, but support the cognitive hypothesis of action understanding.

  13. Is H Atom Abstraction Important in the Reaction of Cl with 1-Alkenes?

    PubMed

    Walavalkar, M P; Vijayakumar, S; Sharma, A; Rajakumar, B; Dhanya, S

    2016-06-23

    The relative yields of products of the reaction of Cl atoms with 1-alkenes (C4-C9) were determined to see whether H atom abstraction is an important channel and if it is to identify the preferred position of abstraction. The presence of all the possible positional isomers of long chain alkenones and alkenols among the products, along with chloroketones and chloroalcohols, confirms the occurrence of H atom abstraction. A consistent pattern of distribution of abstraction products is observed with oxidation at C4 (next to allyl) being the lowest and that at CH2 groups away from the double bond being the highest. This contradicts with the higher stability of allyl (C3) radical. For a better understanding of the relative reactivity, ab initio calculations at MP2/6-311+G (d,p) level of theory are carried out in the case of 1-heptene. The total rate coefficient, calculated using conventional transition state theory, was found to be in good agreement with the experimental value at room temperature. The preferred position of Cl atom addition is predicted to be the terminal carbon atom, which matches with the experimental observation, whereas the rate coefficients calculated for individual channels of H atom abstraction do not explain the observed pattern of products. The distribution of abstraction products except at C4 is found to be better explained by reported structure activity relationship, developed from experimental rate coefficient data. This implies the reactions to be kinetically dictated and emphasizes the importance of secondary reactions.

  14. How language enables abstraction: a study in computational cultural psychology.

    PubMed

    Neuman, Yair; Turney, Peter; Cohen, Yohai

    2012-06-01

    The idea that language mediates our thoughts and enables abstract cognition has been a key idea in socio-cultural psychology. However, it is not clear what mechanisms support this process of abstraction. Peirce argued that one mechanism by which language enables abstract thought is hypostatic abstraction, the process through which a predicate (e.g., dark) turns into an object (e.g., darkness). By using novel computational tools we tested Peirce's idea. Analysis of the data provides empirical support for Peirce's mechanism and evidence of the way the use of signs enables abstraction. These conclusions are supported by the in-depth analysis of two case studies concerning the abstraction of sweet and dark. The paper concludes by discussing the findings from a broad and integrative theoretical perspective and by pointing to computational cultural psychology as a promising perspective for addressing long-lasting questions of the field.

  15. An evaluation of 'Inpharma', a drug literature abstracting service.

    PubMed

    Milne, A

    1981-09-01

    This study aimed to provide data on the characteristics of the drug literature abstracting service 'Inpharma'. Journal coverage, article yield and timeliness for a 3-year period were examined; the reliability and information content of 100 abstracts were also assessed. It was found that although 'Inpharma' is claimed to monitor a very large number of journals, over 98% of the abstracts were from 'core' journals of which there are approximately 350. Over 80% of the abstracts appeared within 4 months of publications of the original and abstracts from some of the American journals were available in the United Kingdom before the relevant primary journal. Sixteen errors were detected in 100 abstracts; five of these were typographical errors and nine deviations in accuracy. The publication is a good 'current awareness tool' but it should not be used where a comprehensive coverage of the literature is required. It is also important that the primary journal is consulted when detailed information is required.

  16. Reporting completeness of abstracts of systematic reviews published in leading dental specialty journals.

    PubMed

    Seehra, Jadbinder; Fleming, Padhraig S; Polychronopoulou, Argy; Pandis, Nikolaos

    2013-04-01

    The aim of this study was to investigate the reporting completeness of systematic review (SR) abstracts in leading dental specialty journals. Electronic and supplementary hand searching were undertaken to identify SRs published in seven dental specialty journals and in the Cochrane Database of Systematic Reviews. Abstract reporting completeness was evaluated using a checklist derived from the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (prisma) guidelines. Descriptive statistics followed by univariate and multivariate analyses were conducted. Two-hundred and eighteen SR abstracts were identified. Reporting of interventions (94%), objectives (96%), data sources (81%), eligibility criteria (77%), and conclusions (97%) was adequate in the majority of reviews. However, inadequate reporting of participants (18%), results (42%), effect size (14%), level of significance (60%), and trial registration (100%) was commonplace. The mean overall reporting score was 79.1% (95% CI, 77.6-80.6). Only journal of publication was a significant predictor of overall reporting, with inferior results for all journals relative to Cochrane reviews, with scores ranging from -4.3% (95% CI, -8.74 to 0.08) to -35.6% (95% CI, -42.0 to -24.3) for the International Journal of Prosthodontics and the British Journal of Oral and Maxillofacial Surgery, respectively. Improved reporting of dental SR abstracts is needed and should be encouraged, as these abstracts may underpin influential clinical decisions.

  17. Modularity in Non-Procedural Languages through Abstract Data Types.

    DTIC Science & Technology

    1980-08-31

    modularity Nopal 20. ABSTRACT (Coftiue an reverse aide It necessary Wnd Idaitfy by WOek nursbr) iThis dissertation presents abstract data tipes as a means...UNCLASSIFIED KEYWORDS cont. Nopal processor Equate-Atlas Equational specifications ABSTRACT cont. these languages because these are devoid of any control...and its denotational semantics is given. Nopal , a non-procedural language for the specification of testing of electrical circuits, has been chosen in

  18. Abstract models for the synthesis of optimization algorithms.

    NASA Technical Reports Server (NTRS)

    Meyer, G. G. L.; Polak, E.

    1971-01-01

    Systematic approach to the problem of synthesis of optimization algorithms. Abstract models for algorithms are developed which guide the inventive process toward ?conceptual' algorithms which may consist of operations that are inadmissible in a practical method. Once the abstract models are established a set of methods for converting ?conceptual' algorithms falling into the class defined by the abstract models into ?implementable' iterative procedures is presented.

  19. Effective use of tables and figures in abstracts, presentations, and papers.

    PubMed

    Durbin, Charles G

    2004-10-01

    In some situations, tables, graphs, and figures can present certain types of information (including complicated relationships and sequences of events) more clearly and in less space than the same information would require in sentence form. However, do not use tables, graphs, and figures for small amounts of data that could be conveyed clearly and succinctly in a sentence. Also, do not reiterate in sentences the data that are shown in a table, graph, or figure: the point of creating a table or graph or figure is to eliminate that type of sentence from your manuscript. In building a data table you must balance the necessity that the table be complete with the equally important necessity that it not be too complex. Sometimes it is helpful to break a large table into several smaller ones to allow the reader to identify important information easily, but, conversely, it is a common mistake of novice authors to split up into several tables data that belong in one table. In almost all cases, only one table or graph or figure should be included in an abstract, and then only if it can convey essential information in less space and in a more easily interpretable way than the sentence form. For a poster, in almost all instances you should use only one typeface and one font in a table, graph, or figure. In general, do not use bold, italics, or color unless you are presenting a great deal of data and you need to highlight certain data values and you are certain that using bold, italics, or color will improve readability, which is rare. Do not include identical information in a table and a graph/figure. In reporting a clinical trial you will need to include a patient flow chart that identifies the number of patients initially screened for the study, the number of patients who were excluded (and why) after initial screening or in the final analysis, and how many patients entered, exited early, and completed each arm of the study. A treatment protocol should also be described with

  20. A quantitative empirical analysis of the abstract/concrete distinction.

    PubMed

    Hill, Felix; Korhonen, Anna; Bentz, Christian

    2014-01-01

    This study presents original evidence that abstract and concrete concepts are organized and represented differently in the mind, based on analyses of thousands of concepts in publicly available data sets and computational resources. First, we show that abstract and concrete concepts have differing patterns of association with other concepts. Second, we test recent hypotheses that abstract concepts are organized according to association, whereas concrete concepts are organized according to (semantic) similarity. Third, we present evidence suggesting that concrete representations are more strongly feature-based than abstract concepts. We argue that degree of feature-based structure may fundamentally determine concreteness, and we discuss implications for cognitive and computational models of meaning.

  1. Selected Translated Abstracts of Chinese-Language Climate Change Publications

    SciTech Connect

    Cushman, R.M.; Burtis, M.D.

    1999-05-01

    This report contains English-translated abstracts of important Chinese-language literature concerning global climate change for the years 1995-1998. This body of literature includes the topics of adaptation, ancient climate change, climate variation, the East Asia monsoon, historical climate change, impacts, modeling, and radiation and trace-gas emissions. In addition to the biological citations and abstracts translated into English, this report presents the original citations and abstracts in Chinese. Author and title indexes are included to assist the reader in locating abstracts of particular interest.

  2. Abstraction of Si and SiH x ( x=1, 2, 3) adsorbed on Cu(1 0 0) surfaces with gaseous H(D) towards silane

    NASA Astrophysics Data System (ADS)

    Kolovos-Vellianitis, D.; Kammler, Th.; Zecho, Th.; Küppers, J.

    2001-09-01

    The interaction of silane and disilane with Cu(1 0 0) surfaces was studied in the temperature range 77-650 K with thermal desorption and Auger electron spectroscopies. Silane admission to Cu(1 0 0) at low temperatures initially leads to a complete decomposition of the silanes into adsorbed Si and H. Close to saturation of the surface with H, SiH x species remain intact on the surface. They were identified as SiH 3 and to a smaller extent SiH 2 by monitoring the silane abstraction products and their kinetics during admitting gaseous D to the surface between 77 and 200 K. Silane desorption through recombination of SiH 3 and SiH 2 with adsorbed H occurs around 157 and 224 K, respectively. After hydrogen desorption around 300 K a Si covered surface remains, which can be converted to a clean Cu(1 0 0) surface by activating Si bulk diffusion around 700 K. Adsorbed Si is abstracted from the surface below 200 K by gaseous H via formation of silane through a sequence of four hydrogenation steps. The first hydrogenation reaction is rate determining and is significantly accelerated by increasing the temperature between 77 and 200 K. Above 200 K a thermally unstable SiH x species blocks the abstraction reaction. The reaction kinetics phenomenology is in accordance with an Eley-Rideal scenario.

  3. Concept Representation Reflects Multimodal Abstraction: A Framework for Embodied Semantics.

    PubMed

    Fernandino, Leonardo; Binder, Jeffrey R; Desai, Rutvik H; Pendl, Suzanne L; Humphries, Colin J; Gross, William L; Conant, Lisa L; Seidenberg, Mark S

    2016-05-01

    Recent research indicates that sensory and motor cortical areas play a significant role in the neural representation of concepts. However, little is known about the overall architecture of this representational system, including the role played by higher level areas that integrate different types of sensory and motor information. The present study addressed this issue by investigating the simultaneous contributions of multiple sensory-motor modalities to semantic word processing. With a multivariate fMRI design, we examined activation associated with 5 sensory-motor attributes--color, shape, visual motion, sound, and manipulation--for 900 words. Regions responsive to each attribute were identified using independent ratings of the attributes' relevance to the meaning of each word. The results indicate that these aspects of conceptual knowledge are encoded in multimodal and higher level unimodal areas involved in processing the corresponding types of information during perception and action, in agreement with embodied theories of semantics. They also reveal a hierarchical system of abstracted sensory-motor representations incorporating a major division between object interaction and object perception processes.

  4. SERI photovoltaic subcontract reports: Abstracts and document control information

    NASA Astrophysics Data System (ADS)

    1990-10-01

    This report contains the document control information and abstracts for Solar Energy Research Institute (SERI) Photovoltaic (PV) Program Branch publications resulting from SERI's subcontracted PV research. The information is presented for reports published or distributed from January 1 through July 31, 1990. In the past, copies of the subcontractor reports were distributed to a broad spectrum of researchers in the field of photovoltaics at a considerable cost to the program. In an attempt to reduce costs and ensure that all researchers receive those current publications that are of specific interest to them, this report will outline these publications, organized by technology, on a regular basis. A list of additional publications and sources is included herein to provide the photovoltaic community with other sources of information. All of the documents represented here are available from the National Technical Information Service (NTIS) and can be purchased using the NTIS order form at the end of this document. Further information on a given subcontracted program may be obtained from the SERI technical monitor identified on each Document Control Page.

  5. Quality assurance of the gene ontology using abstraction networks.

    PubMed

    Ochs, Christopher; Perl, Yehoshua; Halper, Michael; Geller, James; Lomax, Jane

    2016-06-01

    The gene ontology (GO) is used extensively in the field of genomics. Like other large and complex ontologies, quality assurance (QA) efforts for GO's content can be laborious and time consuming. Abstraction networks (AbNs) are summarization networks that reveal and highlight high-level structural and hierarchical aggregation patterns in an ontology. They have been shown to successfully support QA work in the context of various ontologies. Two kinds of AbNs, called the area taxonomy and the partial-area taxonomy, are developed for GO hierarchies and derived specifically for the biological process (BP) hierarchy. Within this framework, several QA heuristics, based on the identification of groups of anomalous terms which exhibit certain taxonomy-defined characteristics, are introduced. Such groups are expected to have higher error rates when compared to other terms. Thus, by focusing QA efforts on anomalous terms one would expect to find relatively more erroneous content. By automatically identifying these potential problem areas within an ontology, time and effort will be saved during manual reviews of GO's content. BP is used as a testbed, with samples of three kinds of anomalous BP terms chosen for a taxonomy-based QA review. Additional heuristics for QA are demonstrated. From the results of this QA effort, it is observed that different kinds of inconsistencies in the modeling of GO can be exposed with the use of the proposed heuristics. For comparison, the results of QA work on a sample of terms chosen from GO's general population are presented.

  6. GENE EXPRESSION PROFILING TO IDENTIFY BIOMARKERS OF REPRODUCTIVE TOXICITY

    EPA Science Inventory

    SOT 2005 SESSION ABSTRACT

    GENE EXPRESSION PROFILING TO IDENTIFY BIOMARKERS OF REPRODUCTIVE TOXICITY

    David J. Dix. National Health and Environmental Effects Research Laboratory, Office of Research and Development, US Environmental Protection Agency, Research Triangle...

  7. Identifying Codes on Directed De Bruijn Graphs

    DTIC Science & Technology

    2014-12-19

    ar X iv :1 41 2. 58 42 v1 [ m at h. C O ] 1 8 D ec 2 01 4 Identifying Codes on Directed De Bruijn Graphs Debra Boutin ∗ Department of...Mathematics Hamilton College Victoria Horan † Air Force Research Laboratory Information Directorate December 19, 2014 Abstract For a directed graph G, a t...length at most t is both non-empty and unique. A graph is called t-identifiable if there exists a t-identifying code. This paper shows that the de

  8. Identifying microRNAs that Regulate Neuroblastoma Cell Differentiation

    DTIC Science & Technology

    2014-09-01

    AD_________________ Award Number: W81XWH-13-1-0241 TITLE: Identifying that Regulate Neuroblastoma ...Unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT We identified 14 microRNA candidates that induce neuroblastoma cell differentiation based on a high...content screening of neurite outgrowth — the morphological differentiation marker of neuroblastoma cells. We further validated that the identified

  9. Honors Dissertation Abstracts: A Bounded Qualitative Meta-Study

    ERIC Educational Resources Information Center

    Holman, Debra K.; Banning, James H.

    2012-01-01

    A potential source of useful information about undergraduate honors education can be found in doctoral dissertation abstracts that focus on honors. Debra Holman and James Banning of Colorado State University sought to explore this resource by undertaking a bounded qualitative meta-study of such abstracts using document analysis. Three…

  10. Odors and Air Pollution: A Bibliography with Abstracts.

    ERIC Educational Resources Information Center

    Environmental Protection Agency, Research Triangle Park, NC. Office of Air Programs.

    The annotated bibliography presents a compilation of abstracts which deal with odors as they relate to air pollution. The abstracts are arranged within the following categories: Emission sources; Control methods; Measurement methods; Air quality measurements; Atmospheric interaction; Basic science and technology; Effects-human health;…

  11. Abstracts of Research, July 1973 through June 1974.

    ERIC Educational Resources Information Center

    Ohio State Univ., Columbus. Computer and Information Science Research Center.

    Abstracts of research papers in the fields of computer and information science are given; 72 papers are abstracted in the areas of information storage and retrieval, information processing, linguistic analysis, artificial intelligence, mathematical techniques, systems programing, and computer networks. In addition, the Ohio State University…

  12. Hanford Personnel Dosimeter supporting studies FY-1980. [Lead abstract

    SciTech Connect

    Endres, G.W.R.; Cummings, F.M.; Aldrich, J.M.; Thorson, M.R.; Kathren, R.L.

    1981-02-01

    Separate abstracts were prepared for the 10 sections of this report which describe fundamental characteristics of the Hanford multipurpose personnel dosimeter (HMPD). Abstracts were not prepared for Appendix A and Appendix B which deal with calculated standard deviations for 100 mrem mixed field exposures and detailed calculations of standard deviations, respectively. (KRM)

  13. Journal of Human Services Abstracts. Volume 8. Number 3.

    ERIC Educational Resources Information Center

    Journal of Human Services Abstracts, 1983

    1983-01-01

    This quarterly journal contains abstracts of 150 of the documents recently included in Project SHARE automated database. (Project SHARE is a national clearinghouse for improving the management of human services.) The journal is divided into four parts: the abstracts themselves arranged in alphabetical order by title, a list of personal and…

  14. On Teaching Abstraction in Computer Science to Novices

    ERIC Educational Resources Information Center

    Armoni, Michal

    2013-01-01

    Abstraction is a key concept in CS, one of the most fundamental ideas underlying CS and its practice. However, teaching this soft concept to novices is a very difficult task, as discussed by many CSE experts. This paper discusses this issue, and suggests a general framework for teaching abstraction in CS to novices, a framework that would fit into…

  15. Contextualizing Action for the Abstraction of Scientific Knowledge

    ERIC Educational Resources Information Center

    Saglam, Yilmaz

    2015-01-01

    In this paper, abstraction is associated with an activity in the sense of activity theory by Vygotsky. To him, participation in social activities is a fundamental act for the child in order to achieve higher mental functions. The present paper aimed to experimentally investigate the abstraction process and illustrate how meaning emerges on social…

  16. Innovation Abstracts: Volume XI, Numbers 1-30.

    ERIC Educational Resources Information Center

    Roueche, Suanne D., Ed.

    1989-01-01

    This series of one- to two-page abstracts highlights a variety of innovative approaches to teaching and learning in the community college. Topics covered in the abstracts include: (1) cooperative planning for institutional excellence; (2) rewarding scholarship among community college faculty; (3) in-class debates as a learning strategy; (4)…

  17. 37 CFR 1.72 - Title and abstract.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Title and abstract. 1.72 Section 1.72 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES National Processing Provisions Specification § 1.72 Title and abstract. (a) The title of...

  18. 37 CFR 1.72 - Title and abstract.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2014-07-01 2014-07-01 false Title and abstract. 1.72 Section 1.72 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES National Processing Provisions Specification § 1.72 Title and abstract. (a) The title of...

  19. 37 CFR 1.72 - Title and abstract.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Title and abstract. 1.72 Section 1.72 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES National Processing Provisions Specification § 1.72 Title and abstract. (a) The title of...

  20. 37 CFR 1.72 - Title and abstract.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2012-07-01 2012-07-01 false Title and abstract. 1.72 Section 1.72 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES National Processing Provisions Specification § 1.72 Title and abstract. (a) The title of...

  1. Effects of Abstract and Concrete Simulation Elements on Science Learning

    ERIC Educational Resources Information Center

    Jaakkola, T.; Veermans, K.

    2015-01-01

    Contemporary evidence on the effectiveness of concrete and abstract representations in science education is based solely on studies conducted in college context. There it has been found that learning with abstract representations produces predominantly better outcomes than learning with concrete representations and combining the representations…

  2. A Quantitative Empirical Analysis of the Abstract/Concrete Distinction

    ERIC Educational Resources Information Center

    Hill, Felix; Korhonen, Anna; Bentz, Christian

    2014-01-01

    This study presents original evidence that abstract and concrete concepts are organized and represented differently in the mind, based on analyses of thousands of concepts in publicly available data sets and computational resources. First, we show that abstract and concrete concepts have differing patterns of association with other concepts.…

  3. The Acquisition of Abstract Words by Young Infants

    ERIC Educational Resources Information Center

    Bergelson, Elika; Swingley, Daniel

    2013-01-01

    Young infants' learning of words for abstract concepts like "all gone" and "eat," in contrast to their learning of more concrete words like "apple" and "shoe," may follow a relatively protracted developmental course. We examined whether infants know such abstract words. Parents named one of two events shown in side-by-side videos while their…

  4. Metagenomic Classification Using an Abstraction Augmented Markov Model

    PubMed Central

    Zhu, Xiujun (Sylvia)

    2016-01-01

    Abstract The abstraction augmented Markov model (AAMM) is an extension of a Markov model that can be used for the analysis of genetic sequences. It is developed using the frequencies of all possible consecutive words with same length (p-mers). This article will review the theory behind AAMM and apply the theory behind AAMM in metagenomic classification. PMID:26618474

  5. Tense Use and Move Analysis in Journal Article Abstracts

    ERIC Educational Resources Information Center

    Wang, Shih-ping; Tu, Pin-ning

    2014-01-01

    There has long been a growing interest in journal article (JA) abstract writing, and this pervading interest has boosted the exigency for further research. This current study therefore aims to investigate both the various applications of verb tense and the rhetorical structure within JA abstracts. A corpus of 1,000 JAs was collected from four…

  6. Economic Education Projects: Abstracts from the 1980-81 Competition.

    ERIC Educational Resources Information Center

    Palmer, George E., Ed.

    Abstracts of innovative and imaginative economics units are provided in this annotated listing of economic education projects submitted to the 1980-81 National Awards Program for Teaching Economics. Over 200 abstracts are contained in separate sections covering materials for primary grades, intermediate grades, junior high schools, senior high…

  7. Reading and Abstracting Journal Articles in Sedimentology and Stratigraphy.

    ERIC Educational Resources Information Center

    Conrad, Susan Howes

    1991-01-01

    An assignment centered on reading journal articles and writing abstracts is an effective way to improve student reading and writing skills in sedimentology and stratigraphy laboratories. Each student reads two articles and writes informative abstracts from the author's point of view. (PR)

  8. Predicting Semantic Changes in Abstraction in Tutor Responses to Students

    ERIC Educational Resources Information Center

    Lipschultz, Michael; Litman, Diane; Katz, Sandra; Albacete, Patricia; Jordan, Pamela

    2014-01-01

    Post-problem reflective tutorial dialogues between human tutors and students are examined to predict when the tutor changed the level of abstraction from the student's preceding turn (i.e., used more general terms or more specific terms); such changes correlate with learning. Prior work examined lexical changes in abstraction. In this work, we…

  9. International symposium on erosion and landscape evolution abstracts

    Technology Transfer Automated Retrieval System (TEKTRAN)

    This book contains all of the extended abstracts from the ASABE specialty conference, the International Symposium on Erosion and Landscape Evolution (ISELE), held September 18-21, 2011 at the Hilton Anchorage Hotel in Anchorage, Alaska. Three extended abstracts from the meeting keynote speakers as ...

  10. South Carolina Higher Education Statistical Abstract, 2014. 36th Edition

    ERIC Educational Resources Information Center

    Armour, Mim, Ed.

    2014-01-01

    The South Carolina Higher Education Statistical Abstract is a comprehensive, single-source compilation of tables and graphs which report data frequently requested by the Governor, Legislators, college and university staff, other state government officials, and the general public. The 2014 edition of the Statistical Abstract marks the 36th year of…

  11. Mercury and Air Pollution: A Bibliography With Abstracts.

    ERIC Educational Resources Information Center

    Environmental Protection Agency, Research Triangle Park, NC. Office of Air Programs.

    The Air Pollution Technical Information Center (APTIC) of the Office of Air Programs has selected and compiled this bibliography of abstracts on mercury and air pollution. The abstracted documents are considered representative of available literature, although not all-inclusive. They are grouped into eleven categories: (1) Emission Sources, (2)…

  12. Innovation Abstracts, Volume XIII, Numbers 1-30, 1991.

    ERIC Educational Resources Information Center

    Roueche, Suanne D., Ed.

    1991-01-01

    This series of one- to two-page abstracts highlights a variety of innovative approaches to teaching and learning in the community college. Topics covered in the abstracts include: (1) internationalizing the curriculum through focused interaction; (2) improving the small group approach to learning; (3) writing across the curriculum with early essay…

  13. Innovation Abstracts: Volume XII, Numbers 1-30, 1990.

    ERIC Educational Resources Information Center

    Roueche, Susanne D., Ed.

    1990-01-01

    This series of one- to two-page abstracts highlights a variety of innovative approaches to teaching and learning in the community college. Topics covered in the abstracts include: (1) academic partnerships pairing "high-risk" students with a concerned faculty member, counselor, or administrator; (2) teacher-to-teacher learning partnerships; (3)…

  14. Concept Abstractness and the Representation of Noun-Noun Combinations

    ERIC Educational Resources Information Center

    Xu, Xu; Paulson, Lisa

    2013-01-01

    Research on noun-noun combinations has been largely focusing on concrete concepts. Three experiments examined the role of concept abstractness in the representation of noun-noun combinations. In Experiment 1, participants provided written interpretations for phrases constituted by nouns of varying degrees of abstractness. Interpretive focus (the…

  15. A Dialectical Approach to the Formation of Mathematical Abstractions

    ERIC Educational Resources Information Center

    Ozmantar, Mehmet Fatih; Monaghan, John

    2007-01-01

    This paper is structured in two sections. The first examines views of mathematical abstraction in two broad categories: empiricist and dialectical accounts. It documents the difficulties involved in and explores the potentialities of both accounts. Then it outlines a recent model which takes a dialectical materialist approach to abstraction in…

  16. Bilingual Vocational Education. Project Abstracts 1987-1988.

    ERIC Educational Resources Information Center

    Office of Vocational and Adult Education (ED), Washington, DC.

    Abstracts are provided for 16 bilingual vocational education projects offered in 1987-88. Each abstract provides information on: grantee; state; project title; project director, address, and telephone number; project officer and U.S. Department of Education address; language group(s) served; occupational skills area(s); length of training cycle…

  17. Ecological Research Division Theoretical Ecology Program. [Contains abstracts

    SciTech Connect

    Not Available

    1990-10-01

    This report presents the goals of the Theoretical Ecology Program and abstracts of research in progress. Abstracts cover both theoretical research that began as part of the terrestrial ecology core program and new projects funded by the theoretical program begun in 1988. Projects have been clustered into four major categories: Ecosystem dynamics; landscape/scaling dynamics; population dynamics; and experiment/sample design.

  18. Knowledge Base Refinement by Monitoring Abstract Control Knowledge.

    ERIC Educational Resources Information Center

    Wilkins, D. C.; And Others

    Arguing that an explicit representation of the problem-solving method of an expert system shell as abstract control knowledge provides a powerful foundation for learning, this paper describes the abstract control knowledge of the Heracles expert system shell for heuristic classification problems, and describes how the Odysseus apprenticeship…

  19. The Transfer of Abstract Principles Governing Complex Adaptive Systems

    ERIC Educational Resources Information Center

    Goldstone, Robert L.; Sakamoto, Yasuaki

    2003-01-01

    Four experiments explored participants' understanding of the abstract principles governing computer simulations of complex adaptive systems. Experiments 1, 2, and 3 showed better transfer of abstract principles across simulations that were relatively dissimilar, and that this effect was due to participants who performed relatively poorly on the…

  20. Levels of abstraction in orangutan (Pongo abelii) categorization.

    PubMed

    Vonk, Jennifer; MacDonald, Suzanne E

    2004-03-01

    Levels of abstraction have rarely been manipulated in studies of natural concept formation in nonhumans. Isolated examples have indicated that animals, relative to humans, may learn concepts at varying levels of abstraction with differential ease. The ability of 6 orangutans (Pongo abelii) of various ages to make natural concept discriminations at 3 levels of abstraction was therefore investigated. The orangutans were rewarded for selecting photos of orangutans instead of humans and other primates (concrete level), primates instead of other animals (intermediate level), and animals instead of nonanimals (abstract level) in a 2-choice touch screen procedure. The results suggest that, like a gorilla (Gorilla gorilla gorilla) tested previously (Vonk & MacDonald, 2002), orangutans can learn concepts at each level of abstraction, and unlike other nonhumans, most of these subjects rapidly learned the intermediate level discrimination.

  1. Visual categorization: accessing abstraction in non-human primates.

    PubMed Central

    Fabre-Thorpe, Michèle

    2003-01-01

    Evolution might have set the basic foundations for abstract mental representation long ago. Because of language, mental abilities would have reached different degrees of sophistication in mammals and in humans but would be, essentially, of the same nature. Thus, humans and animals might rely on the same basic mechanisms that could be masked in humans by the use of sophisticated strategies. In this paper, monkey and human abilities are compared in a variety of perceptual tasks including visual categorization to assess behavioural similarities and dissimilarities, and to determine the level of abstraction of monkeys' mental representations. The question of how these abstract representations might be encoded in the brain is then addressed. A comparative study of the neural processing underlying abstract cognitive operations in animals and humans might help to understand when abstraction emerged in the phylogenetic scale, and how it increased in complexity. PMID:12903657

  2. Methods for solving reasoning problems in abstract argumentation - A survey.

    PubMed

    Charwat, Günther; Dvořák, Wolfgang; Gaggl, Sarah A; Wallner, Johannes P; Woltran, Stefan

    2015-03-01

    Within the last decade, abstract argumentation has emerged as a central field in Artificial Intelligence. Besides providing a core formalism for many advanced argumentation systems, abstract argumentation has also served to capture several non-monotonic logics and other AI related principles. Although the idea of abstract argumentation is appealingly simple, several reasoning problems in this formalism exhibit high computational complexity. This calls for advanced techniques when it comes to implementation issues, a challenge which has been recently faced from different angles. In this survey, we give an overview on different methods for solving reasoning problems in abstract argumentation and compare their particular features. Moreover, we highlight available state-of-the-art systems for abstract argumentation, which put these methods to practice.

  3. Head-Strictness is Not a Monotonic Abstract Property

    NASA Technical Reports Server (NTRS)

    Kamin, Samuel

    1991-01-01

    A property P of a language is said to be definable by abstract interpretation if there is a monotonic map abs from the domain of standard semantics to an abstract domain A of finite height, and a partition of the abstract domain into two parts A(sub p) and A(sub non p), such that any value has property P if and only if abs maps it to an element of A(sub p). Head-strictness is a property of functions over lists which asserts, roughly speaking, that whenever the function looks at the tail of a list, it looks at the head of the tail. We prove that head-strictness is not definable by abstract interpretation. We then present a non-monotonic abstract interpretation for head-strictness and prove its safety.

  4. Enhancements to the NASA Astrophysics Science Information and Abstract Service

    NASA Astrophysics Data System (ADS)

    Kurtz, M. J.; Eichhorn, G.; Accomazzi, A.; Grant, C. S.; Murray, S. S.

    1995-05-01

    The NASA Astrophysics Data System Astrophysics Science Information and Abstract Service, the extension of the ADS Abstract Service continues rapidly to expand in both use and capabilities. Each month the service is used by about 4,000 different people, and returns about 1,000,000 pieces of bibliographic information. Among the recent additions to the system are: 1. Whole Text Access. In addition to the ApJ Letters we now have whole text for the ApJ on-line, soon we will have AJ and Rev. Mexicana. Discussions with other publishers are in progress. 2. Space Instrumentation Database. We now provide a second abstract service, covering papers related to space instruments. This is larger than the astronomy and astrophysics database in terms of total abstracts. 3. Reference Books and Historical Journals. We have begun putting the SAO Annals and the HCO Annals on-line. We have put the Handbook of Space Astronomy and Astrophysics by M.V. Zombeck (Cambridge U.P.) on-line. 4. Author Abstracts. We can now include original abstracts in addition to those we get from the NASA STI Abstracts Database. We have included abstracts for A&A in collaboration with the CDS in Strasbourg, and are collaborating with the AAS and the ASP on others. We invite publishers and editors of journals and conference proceedings to include their original abstracts in our service; send inquiries via e-mail to ads@cfa.harvard.edu. 5. Author Notes. We now accept notes and comments from authors of articles in our database. These are arbitrary html files and may contain pointers to other WWW documents, they are listed along with the abstracts, whole text, and data available in the index listing for every reference. The ASIAS is available at: http://adswww.harvard.edu/

  5. Multi-dimensional temporal abstraction and data mining of medical time series data: trends and challenges.

    PubMed

    Catley, Christina; Stratti, Heidi; McGregor, Carolyn

    2008-01-01

    This paper presents emerging trends in the area of temporal abstraction and data mining, as applied to multi-dimensional data. The clinical context is that of Neonatal Intensive Care, an acute care environment distinguished by multi-dimensional and high-frequency data. Six key trends are identified and classified into the following categories: (1) data; (2) results; (3) integration; and (4) knowledge base. These trends form the basis of next-generation knowledge discovery in data systems, which must address challenges associated with supporting multi-dimensional and real-world clinical data, as well as null hypothesis testing. Architectural drivers for frameworks that support data mining and temporal abstraction include: process-level integration (i.e. workflow order); synthesized knowledge bases for temporal abstraction which combine knowledge derived from both data mining and domain experts; and system-level integration.

  6. Reducing Abstraction in High School Computer Science Education: The Case of Definition, Implementation, and Use of Abstract Data Types

    ERIC Educational Resources Information Center

    Sakhnini, Victoria; Hazzan, Orit

    2008-01-01

    The research presented in this article deals with the difficulties and mental processes involved in the definition, implementation, and use of abstract data types encountered by 12th grade advanced-level computer science students. Research findings are interpreted within the theoretical framework of "reducing abstraction" [Hazzan 1999]. The…

  7. Marking Identifiable Scripts: Following up Student Concerns

    ERIC Educational Resources Information Center

    Owen, Cathy; Stefaniak, John; Corrigan, Gerry

    2010-01-01

    Introduction: Medical student concern that the submission of named examination scripts to examiners could cause bias initiated a study on the effect of identified and de-identified scripts on assessment outcome. Methods: Data were collected from a convenience examination sample of Year 1 (n = 88 students; n = 29 questions) and Year 2 scripts (n =…

  8. Concrete Model Checking with Abstract Matching and Refinement

    NASA Technical Reports Server (NTRS)

    Pasareanu Corina S.; Peianek Radek; Visser, Willem

    2005-01-01

    We propose an abstraction-based model checking method which relies on refinement of an under-approximation of the feasible behaviors of the system under analysis. The method preserves errors to safety properties, since all analyzed behaviors are feasible by definition. The method does not require an abstract transition relation to he generated, but instead executes the concrete transitions while storing abstract versions of the concrete states, as specified by a set of abstraction predicates. For each explored transition. the method checks, with the help of a theorem prover, whether there is any loss of precision introduced by abstraction. The results of these checks are used to decide termination or to refine the abstraction, by generating new abstraction predicates. If the (possibly infinite) concrete system under analysis has a finite bisimulation quotient, then the method is guaranteed to eventually explore an equivalent finite bisimilar structure. We illustrate the application of the approach for checking concurrent programs. We also show how a lightweight variant can be used for efficient software testing.

  9. Experiencing Art: The Influence of Expertise and Painting Abstraction Level

    PubMed Central

    Pihko, Elina; Virtanen, Anne; Saarinen, Veli-Matti; Pannasch, Sebastian; Hirvenkari, Lotta; Tossavainen, Timo; Haapala, Arto; Hari, Riitta

    2011-01-01

    How does expertise influence the perception of representational and abstract paintings? We asked 20 experts on art history and 20 laypersons to explore and evaluate a series of paintings ranging in style from representational to abstract in five categories. We compared subjective esthetic judgments and emotional evaluations, gaze patterns, and electrodermal reactivity between the two groups of participants. The level of abstraction affected esthetic judgments and emotional valence ratings of the laypersons but had no effect on the opinions of the experts: the laypersons’ esthetic and emotional ratings were highest for representational paintings and lowest for abstract paintings, whereas the opinions of the experts were independent of the abstraction level. The gaze patterns of both groups changed as the level of abstraction increased: the number of fixations and the length of the scanpaths increased while the duration of the fixations decreased. The viewing strategies – reflected in the target, location, and path of the fixations – however indicated that experts and laypersons paid attention to different aspects of the paintings. The electrodermal reactivity did not vary according to the level of abstraction in either group but expertise was reflected in weaker responses, compared with laypersons, to information received about the paintings. PMID:21941475

  10. Initial Staging of Hodgkin’s Disease

    PubMed Central

    Chiaravalloti, Agostino; Danieli, Roberta; Caracciolo, Cristiana Ragano; Travascio, Laura; Cantonetti, Maria; Gallamini, Andrea; Guazzaroni, Manlio; Orlacchio, Antonio; Simonetti, Giovanni; Schillaci, Orazio

    2014-01-01

    Abstract The objective of this study was to compare the diagnostic accuracy of positron emission tomography/low-dose computed tomography (PET/ldCT) versus the same technique implemented by contrast-enhanced computed tomography (ceCT) in staging Hodgkin’s disease (HD). Forty patients (18 men and 22 women, mean age 30 ± 9.6) with biopsy-proven HD underwent a PET/ldCT study for initial staging including an unenhanced low-dose computed tomography for attenuation correction with positron emission tomography acquisition and a ceCT, performed at the end of the PET/ldCT scan, in the same exam session. A detailed datasheet was generated for illness locations for separate imaging modality comparison and then merged in order to compare the separate imaging method results (PET/ldCT and ceCT) versus merged results positron emission tomography/contrast-enhanced computed tomography (PET/ceCT). The nodal and extranodal lesions detected by each technique were then compared with follow-up data that served as the reference standard. No significant differences were found at staging between PET/ldCT and PET/ceCT in our series. One hundred and eighty four stations of nodal involvement have been found with no differences in both modalities. Extranodal involvement was identified in 26 sites by PET/ldCT and in 28 by PET/ceCT. We did not find significant differences concerning the stage (Ann Arbor). Our study shows a good concordance and conjunction between PET/ldCT and ceCT in both nodal and extranodal sites in the initial staging of HD, suggesting that PET/ldCT could suffice in most of these patients. PMID:25121354

  11. Instrumented Pipeline Initiative

    SciTech Connect

    Thomas Piro; Michael Ream

    2010-07-31

    This report summarizes technical progress achieved during the cooperative agreement between Concurrent Technologies Corporation (CTC) and U.S. Department of Energy to address the need for a for low-cost monitoring and inspection sensor system as identified in the Department of Energy (DOE) National Gas Infrastructure Research & Development (R&D) Delivery Reliability Program Roadmap.. The Instrumented Pipeline Initiative (IPI) achieved the objective by researching technologies for the monitoring of pipeline delivery integrity, through a ubiquitous network of sensors and controllers to detect and diagnose incipient defects, leaks, and failures. This report is organized by tasks as detailed in the Statement of Project Objectives (SOPO). The sections all state the objective and approach before detailing results of work.

  12. Quality initiative at ESO

    NASA Astrophysics Data System (ADS)

    Rupprecht, Gero; Arsenault, Robin; Hanuschik, Reinhard; Kraus, Maximilian; Sivera, Paola; Tromp, Arnout; Verzichelli, Gianluca

    2016-08-01

    An initiative is under way at ESO Headquarters to optimise operations, in particular in the engineering, technical and associated management areas. A systematic approach to strengthen the operating processes is in preparation, starting with a mapping of the extensive existing process network. Processes identified as sufficiently important and complex to merit an in-depth analysis will be properly specified and their implementation optimised to strike a sensible balance between organisational overhead (documentation) and efficiency. By applying methods and tools tried and tested in industry we expect to achieve a more unified approach to address recurrent tasks. This will enable staff to concentrate more on new challenges and improvement and avoid spending effort on issues already resolved in the past.

  13. Sail-assisted commercial marine vehicles: bibliography and abstracts

    SciTech Connect

    Shortall, J.W. III

    1983-01-01

    A bibliography that contains abstracts of 331 articles published on the subject of commercial sailing vessels and sail-assisted work boats of all kinds is presented. This is part of a continuing project supported both by the University of South Florida and the Florida Sea Grant College, and is an update of the previous publication of abstracts, Florida Sea Grant College Technical Paper No.24, May, 1982. Abstracts are compiled regularly, and subsequent reports will be issued periodically. A brief discussion of modern and historical commercial sail, the reasons for serious interest in same, and commercial sailing fishing vessels is presented.

  14. Using VPHOT and PTGP to Generate Transformation Coefficients (Abstract)

    NASA Astrophysics Data System (ADS)

    Menzies, K.; Myers, G.

    2015-06-01

    (Abstract only) The AAVSO web site hosts two useful tools, VPHOT and PTGP, to help develop your transformation coefficients. They can be used together to simplify a tedious process involving standard comparison star selection, image reduction and spreadsheet analysis. The process necessary to generate Transformation Coefficients involves: (1) measurement of instrumental magnitudes of Standard Comparison Stars, (2) measurement of instrumental magnitudes for a set of images and filters (UBVRI), and (3) downloading of comparison star magnitude files in a standard format. The subsequent process involves: (4) importing the set of standard comparison star magnitude files into PTGP, and (5) the automatic calculation of transformation coefficients and transformation plots. During testing in vphot and PTGP, simple steps and alternatives have been identified to generate accurate transform coefficients. The first VPHOT step is the obvious need to upload multiple images in multiple standard filters to VPHOT. The second step is to open each image, overlay all standard comparison stars (currently M67 or NGC 7790), view the photometry table, and download the comparison star magnitude data files. Two alternatives involve either the use of individual image files (for example, 4B, 4V, 4R; 4I) or the stacking of all images for each filter (for example, 1B, 1V, 1R; 1I). The latter improves the SNR. In PTGP after the selection of telescope, standard fields, and data reduction software, one selects all comp star magnitude files. The “Calculate Transform Set” button calculates the applicable filter magnitude and color index coefficients. Testing of this process included an evaluation of the impact of several alternatives including: (1) choice of individual filter images or stacked filter images, (2) choice of all standard comparison stars or a selected subset of standard comparison stars, and (3) choice of a minimum SNR. Each of these alternatives affects the transformation

  15. Identification of Cepheid Variables in ASAS Data (Poster abstract)

    NASA Astrophysics Data System (ADS)

    Swenton, V.; Larsen, K.

    2014-06-01

    (Abstract only) Through studying the characteristics of Cepheid variables, we can further understand the nature and evolution of stars, as well as the scale of the Universe (through the famous period-luminosity relationship). Classical Cepheid stars, or Type I Cepheids, are radially-pulsating supergiants. Type II Cepheids are older and have lower mass than Type I Cepheids. They are rarer and existing classifications of these stars have been shown to be erroneous at unusual high rates. Computerized automatic classification programs sift through the data of large photometric surveys to produce a list of (what the program recognizes as) Cepheid star candidates. Unfortunately, this automatic classification of light curves has demonstrated to be ambiguous. Therefore, it takes a human to further sift through the list in order to come up with a more accurate (and, as a result, a more useful) list of probable Cepheids. This study was based on a list of 3,548 Cepheid candidates in the ASAS data provided by Patrick Wils (through Doug Welch). Patrick Wils had previously examined eighty-four stars on the spreadsheet and positively identified only five of these stars as Cepheids. The methodology of the current study was to use known properties of Cepheids including available infrared photometry (2MASS), proper motion (PPMXL), and X-Ray emission (ROTSE) data (for which we received helpful guidance from Sebastian Otero) to cull the list down to the most likely Cepheids. The ASAS light curves of these candidates were investigated to determine whether the shapes were truly consistent with those of Cepheids. This poster will summarize the methodology used and give examples of how individual Cepheid candidates were evaluated. Candidates of interest are currently being crosschecked for any updated information on VSX, and the light curves more closely analyzed using VStar. Results concerning the misidentification of candidate Cepheids will be reported to VSX and summarized in JAAVSO.

  16. Initial blood storage experiment

    NASA Technical Reports Server (NTRS)

    Surgenor, Douglas MACN.

    1988-01-01

    The design of the Initial Blood Storage Experiment (IBSE) was based upon a carefully controlled comparison between identical sets of human blood cell suspensions - red cells, white cell, and platelets - one set of which was transported aboard the Columbia on a 6 day 11 hour mission, and the other held on the ground. Both sets were carried inside stainless steel dewars within specially fabricated flight hardware. Individual bags of cell suspensions were randomly assigned with respect to ground vs orbit status, dewar chamber, and specific location within the dewar. To foster optimal preservation, each cell type was held under specific optimal conditions of pH, ionic strength, solute concentration, gas tension, and temperature. An added variable in this initial experiment was provided by the use of three different polymer/plasticizer formulations for the sealed bags which held the blood cells. At termination of the experiment, aliquots of the suspensions, identified only by code, were distributed to be assayed. Assays were selected to constitute a broad survey of cellular properties and thereby maximize the chances of detection of gravitational effects. A total of 74 different outcome measurements were reported for statistical analysis. When the measurements were completed, the results were entered into the IBSE data base, at which time the data were matched with the original blood bag numbers to determine their status with respect to polymer/plasticizer type, orbit status (orbit or ground), and storage position within the experimental hardware. The data were studied by analysis of variance. Initially, type of bag and orbital status were main factors; later more detailed analyses were made on specific issues such as position in the hardware and specific plastic. If the analysis of variance indicated a statistical significance at the 5 percent level the corresponding p-value was reported.

  17. Initiating Population Education in Baltimore

    ERIC Educational Resources Information Center

    Cochran, Caroline S.; McCrea, Lester C.

    1974-01-01

    After identifying the need for population education in Baltimore City Schools, the school system had the problem of initiating such a course. Working with the Planned Parenthood Association of Maryland, the school system sponsored an in-service program for teachers that resulted in the production of materials for all grades. (MA)

  18. Gang Identifiers and Terminology.

    ERIC Educational Resources Information Center

    Cantrell, Mary Lynn

    1992-01-01

    Provides lists of gang identifiers and terminology. Suggests that, to find out names and associated identifiers of local gangs, readers should talk to their local police. Included in listing are descriptions of gang-related symbols, physical signals, graffiti, slogans, right-left rules, colors, clothing, jewelry, hair styles, and fingernails. Also…

  19. What does the brain tell us about abstract art?

    PubMed Central

    Aviv, Vered

    2014-01-01

    In this essay I focus on the question of why we are attracted to abstract art (perhaps more accurately, non-representational or object-free art). After elaborating on the processing of visual art in general and abstract art in particular, I discuss recent data from neuroscience and behavioral studies related to abstract art. I conclude with several speculations concerning our apparent appeal to this particular type of art. In particular, I claim that abstract art frees our brain from the dominance of reality, enabling it to flow within its inner states, create new emotional and cognitive associations, and activate brain-states that are otherwise harder to access. This process is apparently rewarding as it enables the exploration of yet undiscovered inner territories of the viewer’s brain. PMID:24616683

  20. Abstract Proceedings Signal and Imaging Sciences Workshop CASIS Workshop 2006

    SciTech Connect

    Roberts, R

    2006-11-07

    These abstracts cover the following topics: (1) Analysis of massive datasets; (2) Nondestructive evaluation; (3) Imaging methodology; (4) NIF optics inspection; (5) Model-based signal processing and estimation; and (6) Image processing and analysis.