Science.gov

Sample records for abuse special emphasis

  1. Managing Chronic Pain in Special Populations with Emphasis on Pediatric, Geriatric, and Drug Abuser Populations

    PubMed Central

    Baumbauer, Kyle M.; Young, Erin E.; Starkweather, Angela R.; Guite, Jessica W.; Russell, Beth S.; Manworren, Renee C.

    2015-01-01

    Synopsis Chronic pain represents a significant health and societal concern. In the adult population chronic pain can lead to loss of productivity, earning potential, and decreased quality of life. Research has typically focused on otherwise healthy adults with chronic pain conditions; however there appear to be distinct groups with increased vulnerability for the emergence of chronic pain. These groups may be defined by developmental status and/or life circumstances that increase the risk of injury or for which treatment of pain is less effective. Within the pediatric, geriatric, and drug abuser populations, chronic pain also represents a significant health issue, which can lead to increased absenteeism during school age years, as well as decreased quality of life and increased risk of additional adverse health conditions later in life. Currently, little is known about the mechanisms that encourage the development of chronic pain in these groups, and, consequently, pediatric, geriatric, and substance abuse patients represent challenging cohorts to manage. We focus on known anatomic, physiologic, and genetic mechanisms underlying chronic pain in these populations, and highlight the need for a multimodal approach from multiple healthcare professionals for management of chronic pain in those with the most risk. PMID:26614727

  2. 78 FR 63207 - Special Emphasis Panel; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-23

    ... HUMAN SERVICES Agency for Healthcare Research and Quality Special Emphasis Panel; Meeting AGENCY: Agency... Healthcare Research and Quality (AHRQ) Special Emphasis Panel (SEP) meeting on ``AHRQ RFA-HS-13-010, Closing... meeting are subject to change as priorities dictate. SUPPLEMENTARY INFORMATION: A Special Emphasis...

  3. 78 FR 5184 - Special Emphasis Panel Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-24

    ... HUMAN SERVICES Agency for Healthcare Research and Quality Special Emphasis Panel Meeting AGENCY: Agency... Healthcare Research and Quality (AHRQ) Special Emphasis Panel (SEP) meeting on ``Patient Centered Outcomes... INFORMATION: A Special Emphasis Panel is a group of experts in fields related to health care research who...

  4. 77 FR 55477 - Special Emphasis Panel Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-10

    ... HUMAN SERVICES Agency for Healthcare Research And Quality Special Emphasis Panel Meeting AGENCY: Agency... Agency for Healthcare Research and Quality (AHRQ) Special Emphasis Panel (SEP) meeting on ``Partnerships... subject to change as priorities dictate. SUPPLEMENTARY INFORMATION: A Special Emphasis Panel is a group...

  5. Let's Prevent Abuse: A Prevention Handbook for Early Childhood Professionals and Families with Young Children, with Special Emphasis on the Needs of Children with Disabilities.

    ERIC Educational Resources Information Center

    Jones, Deb; Martinson, Sue Ann, Ed.

    This handbook on preventing child abuse is intended to help families with young children, especially young children who have or are at risk for disabilities, and to help people working with such families. After an introductory section which presents basic definitions, the first chapter presents highlights of the Education of the Handicapped Act…

  6. Abuse and the Special Child.

    ERIC Educational Resources Information Center

    Murphy, Linda; Corte, Suzanne Della

    1987-01-01

    The issue's major feature, on physical and sexual abuse of handicapped children, focuses on education and adult awareness of the problem. It has been well documented that children with handicaps are especially vulnerable to abuse. Parents or other adults who believe that abuse has occurred should first write down exactly what the child has told…

  7. 78 FR 58320 - National Institute on Drug Abuse; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-23

    ... Committee: National Institute on Drug Abuse Special Emphasis Panel GOMED: Grand Opportunity in Medications... Institute on Drug Abuse Special Emphasis Panel Strategic Alliances for Medications Development to Treat... Drug Abuse Special Emphasis Panel; Medications Development Centers of Excellence Cooperative...

  8. Pycnodysostosis with Special Emphasis on Dentofacial Characteristics

    PubMed Central

    Khoja, Aisha; Fida, Mubassar; Shaikh, Attiya

    2015-01-01

    Pycnodysostosis is an autosomal recessive disorder that manifests as osteosclerosis of the skeleton due to the defective osteoclasts mediated bone turnover. The diagnosis of this disorder is established on the basis of its characteristic features and must be differentially diagnosed with other bone disorders. Dental surgeons should be aware of the limitations and possible adverse oral complications such as osteomyelitis of bone in these patients. This will guide them in planning realistic treatment goals. This paper reports the clinical and radiographic features of pycnodysostosis with the great emphasis on its dentofacial characteristics. The aim of this case report is to give an insight into the etiology, pathogenesis, and differential diagnosis of this disorder and to prepare the dentists and maxillofacial surgeons to overcome the challenges in treating these patients. PMID:26649209

  9. Space Construction System Analysis. Special Emphasis Studies

    NASA Technical Reports Server (NTRS)

    1979-01-01

    Generic concepts were analyzed to determine: (1) the maximum size of a deployable solar array which might be packaged into a single orbit payload bay; (2) the optimal overall shape of a large erectable structure for large satellite projects; (3) the optimization of electronic communication with emphasis on the number of antennas and their diameters; and (4) the number of beams, traffic growth, and projections and frequencies were found feasible to package a deployable solar array which could generate over 250 kilowatts of electrical power. Also, it was found that the linear-shaped erectable structure is better for ease of construction and installation of systems, and compares favorably on several other counts. The study of electronic communication technology indicated that proliferation of individual satellites will crowd the spectrum by the early 1990's, so that there will be a strong tendency toward a small number of communications platforms over the continental U.S.A. with many antennas and multiple spot beams.

  10. Pycnodysostosis with Special Emphasis on Dentofacial Characteristics.

    PubMed

    Khoja, Aisha; Fida, Mubassar; Shaikh, Attiya

    2015-01-01

    Pycnodysostosis is an autosomal recessive disorder that manifests as osteosclerosis of the skeleton due to the defective osteoclasts mediated bone turnover. The diagnosis of this disorder is established on the basis of its characteristic features and must be differentially diagnosed with other bone disorders. Dental surgeons should be aware of the limitations and possible adverse oral complications such as osteomyelitis of bone in these patients. This will guide them in planning realistic treatment goals. This paper reports the clinical and radiographic features of pycnodysostosis with the great emphasis on its dentofacial characteristics. The aim of this case report is to give an insight into the etiology, pathogenesis, and differential diagnosis of this disorder and to prepare the dentists and maxillofacial surgeons to overcome the challenges in treating these patients.

  11. 77 FR 54919 - National Institute on Drug Abuse; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-06

    ... Committee: National Institute on Drug Abuse Special Emphasis Panel; Grand Opportunities in Medications... Institute on Drug Abuse Special Emphasis Panel; Strategic Alliances for Medications Development to...

  12. 75 FR 36429 - National Institute on Drug Abuse; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-25

    ... Committee: National Institute on Drug Abuse Special Emphasis Panel, Medications Development for Substance...@nida.nih.gov . Name of Committee: National Institute on Drug Abuse Special Emphasis Panel,...

  13. 62 FR 2692 - Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice Of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1997-01-17

    ... From the Federal Register Online via the Government Publishing Office NATIONAL SCIENCE FOUNDATION Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice Of Meeting In accordance... announces the following meeting. Name: Special Emphasis Panel in Information, Robotics and Intelligent...

  14. 60 FR 14306 - Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1995-03-16

    ... Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting In accordance... announces the following meeting: Name: Special Emphasis Panel in Information, Robotics and Intelligent..., Acting Deputy Division Director, Robotics and Intelligence, Room 1115, National Science Foundation,...

  15. 61 FR 16126 - Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1996-04-11

    ... Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting In accordance... announces the following meeting. Name: Special Emphasis Panel in Information, Robotics and Intelligent..., Deputy Division Director, Robotics and Intelligent Systems, room 1115N, National Science Foundation,...

  16. 60 FR 57602 - Special Emphasis Panel in Information Robotics and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1995-11-16

    ... Special Emphasis Panel in Information Robotics and Intelligent Systems; Notice of Meeting In accordance... announces the following meeting. Name: Special Emphasis Panel in Information, Robotics and Intelligent..., Acting Deputy Division Director, Robotics and Intelligence, Room 1115, National Science Foundation,...

  17. 61 FR 59247 - Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1996-11-21

    ... From the Federal Register Online via the Government Publishing Office NATIONAL SCIENCE FOUNDATION Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting In accordance... announces the following meeting. Name: Special Emphasis Panel in Information, Robotics and Intelligent...

  18. 61 FR 51726 - Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1996-10-03

    ... From the Federal Register Online via the Government Publishing Office NATIONAL SCIENCE FOUNDATION Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting In accordance... announces the following meeting. Name: Special Emphasis Panel in Information, Robotics and...

  19. 61 FR 25920 - Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice Of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1996-05-23

    ... Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice Of Meeting In accordance... announces the following meeting. Name: Special Emphasis Panel in Information, Robotics and Intelligent... NSF for financial support. Agenda: To review and evaluate Robotics and Machine Intelligence...

  20. 59 FR- Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1994-11-17

    ... FOUNDATION Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting In... Foundation announces the following meeting. Name: Special Emphasis Panel in Information, Robotics and..., Acting Deputy Division Director, Robotics and Intelligence, Room 1115, National Science Foundation,...

  1. 59 FR- Special Emphasis Panel in Information, Robotics and Intelligent Systems; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1994-11-25

    ... FOUNDATION Special Emphasis Panel in Information, Robotics and Intelligent Systems; Meeting In accordance... announces the following meeting. Name: Special Emphasis Panel in Information, Robotics and Intelligent... Division Director, Robotics and Intelligence Room 1115, National Science Foundation, 4201 Wilson...

  2. 62 FR 2693 - Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1997-01-17

    ... From the Federal Register Online via the Government Publishing Office ] NATIONAL SCIENCE FOUNDATION Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting In... Foundation announces the following meeting. Name: Special Emphasis Panel in Information, Robotics...

  3. 60 FR 7798 - Special Emphasis Panel in Information Robotics and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1995-02-09

    ... Special Emphasis Panel in Information Robotics and Intelligent Systems; Notice of Meeting In accordance... announces the following meeting: Name: Special Emphasis Panel in Information Robotics and Intelligent... Deputy Division Director, Robotics and Intelligence, Room 1115, National Science Foundation, 4201...

  4. 60 FR 20777 - Special Emphasis Panel in Information Robotics and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1995-04-27

    ... Special Emphasis Panel in Information Robotics and Intelligent Systems; Notice of Meeting In accordance... announces the following meeting. Name: Special Emphasis Panel in Information, Robotics and Intelligent... Deputy Division Director, Robotics and Intelligence, Room 1115, National Science Foundation, 4201...

  5. 62 FR 115 - Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1997-01-02

    ... From the Federal Register Online via the Government Publishing Office NATIONAL SCIENCE FOUNDATION Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting In accordance... announces the following meeting. Name: Special Emphasis Panel in Information, Robotics and Intelligent...

  6. 60 FR 22413 - Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1995-05-05

    ... Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting In accordance... announces the following meeting. Name: Special Emphasis Panel in Information, Robotics and Intelligent..., Robotics and Intelligence, Room 1115, National Science Foundation, 4201 Wilson Blvd., Arlington, VA...

  7. 60 FR 17827 - Special Emphasis Panel in Information Robotics and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1995-04-07

    ... Special Emphasis Panel in Information Robotics and Intelligent Systems; Notice of Meeting In accordance... announces the following meeting. Name: Special Emphasis Panel in Information Robotics and Intelligent... Moraff, Acting Deputy Division Director, Robotics and Intelligence, Room 1115, National...

  8. 60 FR 9055 - Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1995-02-16

    ... Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting In accordance... announces the following meeting. ] Name: Special Emphasis Panel in Information, Robotics and Intelligent... Deputy Division Director, Robotics and Intelligence, Room 1115, National Science Foundation, 4201...

  9. 60 FR 3276 - Special Emphasis Panel in Information, Robotics and Intelligent Systems; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1995-01-13

    ... Special Emphasis Panel in Information, Robotics and Intelligent Systems; Meeting In accordance with the... the following meeting. Name: Special Emphasis Panel in Information, Robotics and Intelligent Systems... Director, Robotics and Intelligence, Room 1115, National Science Foundation, 4201 Wilson Blvd.,...

  10. 60 FR 57877 - Special Emphasis Panel in Information Robotics and Intelligent Systems; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1995-11-22

    ... Special Emphasis Panel in Information Robotics and Intelligent Systems; Meeting In accordance with the... the following meeting. Name: Special Emphasis Panel in Information, Robotics and Intelligent Systems... Deputy Division Director, Robotics and Intelligence, Room 1115, National Science Foundation, 4201...

  11. 62 FR 115 - Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1997-01-02

    ... From the Federal Register Online via the Government Publishing Office NATIONAL SCIENCE FOUNDATION Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting In accordance... announces the following meeting. Name: Special Emphasis Panel in Information, Robotics and...

  12. 62 FR 2692 - Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1997-01-17

    ... From the Federal Register Online via the Government Publishing Office NATIONAL SCIENCE FOUNDATION Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting In accordance... announces the following meeting. Name: Special Emphasis Panel in Information, Robotics and Intelligent...

  13. 59 FR- Special Emphasis Panel in Information, Robotics and Intelligent Systems; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1994-09-01

    ... FOUNDATION Special Emphasis Panel in Information, Robotics and Intelligent Systems; Meeting In accordance... announces the following meeting. Name: Special Emphasis Panel in Information, Robotics and Intelligent... Director, Robotics and Intelligence Systems, Rm. 1115, National Science Foundation, 4201 Wilson...

  14. 59 FR- Special Emphasis Panel in Information, Robotics and Intelligent Systems; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1994-11-25

    ... FOUNDATION Special Emphasis Panel in Information, Robotics and Intelligent Systems; Meeting In accordance... announces the following meeting. Name: Special Emphasis in Information, Robotics and Intelligent Systems... Director, Robotics and Intelligence, Room 1115, National Science Foundation, 4201 Wilson Blvd.,...

  15. 63 FR 20434 - Special Emphasis Panel in Information, Robotics, and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1998-04-24

    ... From the Federal Register Online via the Government Publishing Office ] NATIONAL SCIENCE FOUNDATION Special Emphasis Panel in Information, Robotics, and Intelligent Systems; Notice of Meeting In... Foundation announces the following meeting. Name: Special Emphasis Panel in Information, Robotics...

  16. 61 FR 57480 - Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice Of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1996-11-06

    ... From the Federal Register Online via the Government Publishing Office NATIONAL SCIENCE FOUNDATION Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice Of Meeting In accordance... announces the following meeting. Name: Special Emphasis Panel in Information Robotics & Intelligent...

  17. 62 FR 999 - Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1997-01-07

    ... From the Federal Register Online via the Government Publishing Office NATIONAL SCIENCE FOUNDATION Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting In accordance... announces the following meeting: Name: Special Emphasis Panel in Information, Robotics and Intelligent...

  18. 61 FR 6866 - Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1996-02-22

    ... Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting In accordance... announces the following meeting. Name: Special Emphasis Panel in Information, Robotics and Intelligent... Division Director, Robotics and Intelligent Systems, room 1115N, National Science Foundation, 4201...

  19. 60 FR 27797 - Special Emphasis Panel in Information Robotics and Intelligent Systems; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1995-05-25

    ... From the Federal Register Online via the Government Publishing Office NATIONAL SCIENCE FOUNDATION Special Emphasis Panel in Information Robotics and Intelligent Systems; Meeting In accordance with the... the following meeting. Name: Special Emphasis Panel in Information Robotics and Intelligent...

  20. 61 FR 15149 - Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1996-04-04

    ... Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting In accordance... announces the following meeting. Name: Special Emphasis Panel in Information, Robotics and Intelligence... Division Director, Robotics and Intelligent Systems, room 1115N, National Science Foundation, 4201...

  1. Determination of triglycerides with special emphasis on biosensors: a review.

    PubMed

    Pundir, C S; Narang, Jagriti

    2013-10-01

    Triglycerides (TG) are transesterification product of fatty acids and glycerol and engaged in the transportation of fats. Elevated triglyceride level is associated with coronary heart disease (CAD), atherosclerosis and hypolipoprotenemia. Convenient and reproducible assay systems based on enzymes are an attractive alternative to conventional analytical methods. Triglyceride biosensors (TGBs) are based on either measurement of oxygen consumed or electron generated from splitting of H2O2, an ultimate product, of immobilized enzymes. TGBs work optimally within 2-900 s, between pH 6.4-8.5 and the potential 0.5-4V. TGBs measure TG level in serum directly and can be used over a period of 14 to 168 days. This review describes the analytic characteristics of various methods available for determination of TGs with special emphasis on TGBs.

  2. Teaching about HIV/AIDS and Abuse: Special Educators' Perspectives.

    ERIC Educational Resources Information Center

    Prater, Mary Anne; Serna, Loretta A.

    1993-01-01

    Researchers examined special educators' attitudes regarding mandated curriculum, readiness for teaching, and responsibility for providing instruction on sex education, HIV/AIDS, sexual abuse, and substance abuse. Teachers supported mandated education, felt most comfortable teaching sex education, and considered parents responsible for teaching the…

  3. 76 FR 27327 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Combining...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-11

    ... Control Special Emphasis Panel (SEP): Combining Subjective and Objective Methods for Quantifying Contact... 3, 2011 (Closed). Place: Teleconference. Contact Person For More Information: Gregory Anderson,...

  4. 75 FR 78999 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Centers for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-17

    ... Control Special Emphasis Panel (SEP): Centers for Autism and Developmental Disabilities Research and... Discussed: The meeting will include the initial review, discussion, and evaluation of ``Centers for...

  5. 76 FR 13414 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Continuation of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-11

    ... Control Special Emphasis Panel: Continuation of the National Mesothelioma Virtual Bank for Translational... initial review, discussion, and evaluation of ``Continuation of the National Mesothelioma Virtual Bank...

  6. 59 FR- Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1994-09-29

    ... FOUNDATION Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting In... Moraff, Acting Deputy Division Director, Robotics and Intelligence Systems, Rm. 1115, National...

  7. 78 FR 43003 - Biomedical Laboratory Research and Development Service, Special Emphasis Panel-Amyotrophic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-18

    ... Lateral Sclerosis (ALS) Brain Bank, Notice of Meeting The Department of Veterans Affairs (VA) gives notice under the Federal Advisory Committee Act, 5 U.S.C. App., that the Special Emphasis Panel--ALS Brain Bank...) (6) and (9)(B). The purpose of this Special Emphasis Panel is to review the VA ALS Brain Bank for...

  8. 62 FR 2693 - Special Emphasis Panel in Information, Robotics and Intelligent System; Notice Of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1997-01-17

    ... Special Emphasis Panel in Information, Robotics and Intelligent System; Notice Of Meeting In accordance... announces the following meeting. Name: Special Emphasis Panel in Information, Robotics and Intelligent (1200... submitted to NSF for financial support. Agenda: To review and evaluate Robotics and Machine and...

  9. 62 FR 116 - Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1997-01-02

    ... Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting In accordance... announces the following meeting. Name: Special Emphasis Panel in Information, Robotics and Intelligent... concerning proposals submitted to NSF for financial support. Agenda: To review and evaluate Robotics...

  10. 62 FR 27074 - Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    1997-05-16

    ... Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meetings This notice is...: Special Emphasis Panel in Information, Robotics and Intelligent Systems (1200). 1. Date: June 2-3, 1997...: Robotics and Machine Intelligence Program Computer Vision. 2. Date: June 9-10, 1997. Contact: Dr....

  11. 76 FR 15328 - National Institute on Drug Abuse; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-21

    ... Committee: National Institute on Drug Abuse Special Emphasis Panel; Research Works: Enrollment Workflow...: Courtyard by Marriott Rockville, 2500 Research Boulevard, Rockville, MD 20850. Contact Person: Lyle Furr... . Name of Committee: National Institute on Drug Abuse Special Emphasis Panel; Research Support...

  12. 76 FR 70463 - National Institute on Drug Abuse; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-14

    ... Committee: National Institute on Drug Abuse Special Emphasis Panel; Preclinical Medications Discovery and... . (Catalogue of Federal Domestic Assistance Program Nos.: 93.279, Drug Abuse and Addiction Research...

  13. 78 FR 6126 - National Institute on Drug Abuse; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-29

    ... Abuse Special Emphasis Panel; Toxicological Evaluations of Potential Medications to Treat Drug Addiction... Domestic Assistance Program Nos.: 93.279, Drug Abuse and Addiction Research Programs, National...

  14. 77 FR 12856 - National Institute on Drug Abuse; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-02

    ... Committee: National Institute on Drug Abuse Special Emphasis Panel, Integration of Treatment and Prevention....: 93.279, Drug Abuse and Addiction Research Programs, National Institutes of Health, HHS)...

  15. 75 FR 10490 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Member...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-08

    ... Control Special Emphasis Panel (SEP): Member Conflict Review, Program Announcement (PA) 07-318, Initial... review, discussion, and evaluation of ``Member Conflict Review, PA 07- 318.'' Contact Person for...

  16. 75 FR 9606 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Public...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-03

    ... Control Special Emphasis Panel (SEP): Public Health Research on Craniofacial Malformation, Funding... review, discussion, and evaluation of applications received in response to ``Public Health Research on... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH...

  17. 77 FR 3269 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Data...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-23

    ... Prevention (CDC) Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Data... Review Officer, CDC, 4770 Buford Highway NE., Mailstop F-46, Atlanta, Georgia 30341, Telephone: (770)...

  18. 75 FR 77645 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Pregnancy...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-13

    ... Control Special Emphasis Panel (SEP): Pregnancy Risk Assessment Monitoring System (PRAMS), DP11-001 Panel..., discussion, and evaluation of ``Pregnancy Risk Assessment Monitoring System (PRAMS), DP11-001 Panel...

  19. 76 FR 5379 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Pregnancy...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-31

    ... Control Special Emphasis Panel (SEP): Pregnancy Risk Assessment Monitoring System (PRAMS), DP11-001 Panels... Be Discussed: The meeting will include the initial review, discussion, and evaluation of...

  20. 76 FR 3909 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Family...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-21

    ... Control Special Emphasis Panel (SEP): Family History and Diamond Blackfan Anemia, DD11- 010, Initial... ``Family History and Diamond Blackfan Anemia, DD11-010, initial review.'' Contact Person for...

  1. 75 FR 12243 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Translating...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-15

    ... Control Special Emphasis Panel (SEP): Translating Research Into Healthy Eye and Vision Loss Prevention... Research into Healthy Eye and Vision Loss Prevention, RFA DP 10- 004.'' Contact Person for More...

  2. 75 FR 46952 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): National...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-04

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): National Human Immunodeficiency Virus (HIV) Behavioral...

  3. 75 FR 6675 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Human...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Human Immunodeficiency Virus (HIV) Prevention Projects for...

  4. 75 FR 9423 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Impact of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-02

    ... Control Special Emphasis Panel (SEP): Impact of Japanese Encephalitis Vaccination in Cambodia, Funding... Vaccination in Cambodia, FOA CK10-003.'' Contact Person for More Information: Gregory Anderson, M.S.,...

  5. 75 FR 78999 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Maternal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-17

    ... Control Special Emphasis Panel (SEP): Maternal Vitamin D Status and Preterm Birth, DP11-002, Initial... ``Maternal Vitamin D Status and Preterm Birth, DP11-002, initial review.'' Contact Person for...

  6. Special Operations Forces Language and Culture Needs Assessment Project: Training Emphasis: Language and Culture

    DTIC Science & Technology

    2010-02-25

    DATES COVERED (From - To) February 2010 4. TITLE AND SUBTITLE Special Operations Forces Language and Culture Needs Assessment: Training Emphasis...Language and Culture 5a. CONTRACT NUMBER N65236-08-D-6805 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S...ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S) Special Operations Forces Culture and Language Office HQ USSOCOM Attn: SOKL-J7—SOFLO 7701 Tampa Point

  7. 76 FR 4702 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Cooperative...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-26

    ... Control Special Emphasis Panel (SEP): Cooperative Agreement Program for the National Academic Centers of... meeting: Times and Dates: 8 a.m.-5 p.m., February 17, 2011 (Closed). 8 a.m.-5 p.m., February 18, 2011..., Management Analysis and Services Office, CDC, pursuant to Section 10(d) of Public Law 92-463. Matters To...

  8. 78 FR 66938 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-07

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review Notice of Cancellation: This notice concerns.... Department of Health and Human Services, Centers for Disease Control and Prevention, from October 1-16,...

  9. 78 FR 66937 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-07

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Capacity...), the Centers for Disease Control and Prevention (CDC) announces the aforementioned SEP: Times and...

  10. 78 FR 66937 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-07

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Occupational... 10(a)(2) of the Federal Advisory Committee Act (Pub. L. 92-463), the Centers for Disease Control...

  11. 78 FR 66937 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-07

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review Notice of Cancellation: This notice concerns.... Department of Health and Human Services, Centers for Disease Control and Prevention, from October 1-16,...

  12. 76 FR 7217 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Enhanced...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-09

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Enhanced Surveillance for New Vaccine Preventable Disease, Funding... for New Vaccine Preventable Disease, FOA IP11-010, initial review.'' CONTACT PERSON FOR...

  13. 78 FR 62636 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-22

    ... Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Cooperative... the Director, Management Analysis and Services Office, CDC, pursuant to Public Law 92-463. Matters To... received in response to Cooperative Agreement on Occupational Health with the World Health...

  14. 75 FR 30844 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Conducting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-02

    ... Control Special Emphasis Panel (SEP): Conducting Public Health Research in Kenya (Panel B), Funding..., discussion, and evaluation of applications received in response to ``Conducting Public Health Research in... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH...

  15. 75 FR 28810 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Conducting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-24

    ... Control Special Emphasis Panel (SEP): Conducting Public Health Research in Kenya (Panel C), Funding..., discussion, and evaluation of applications received in response to ``Conducting Public Health Research in... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH...

  16. 76 FR 13413 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP); Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-11

    ... Control Special Emphasis Panel (SEP); Meeting Studies at the Animal-Human Interface of Influenza and Other... of Influenza-Associated Community- Acquired Pneumonia in Hospitalized Persons Study, FOA IP11-011..., FOA IP11-012; Influenza Vaccine Efficacy in Tropical and Developing Countries, FOA IP11-013;...

  17. 64 FR 39144 - Disease, Disability and Injury Prevention and Control Special Emphasis Panel: Implementation of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    1999-07-21

    ... Control Special Emphasis Panel: Implementation of the National Occupational Research Agenda (NORA), RFA OH-99-002, Program Area #5, Surveillance Research Methodology In accordance with section 10(a)(2) of the... Area #5, Surveillance Research Methodology, meeting. Times and Dates: 10 a.m.-10:30 a.m., August...

  18. 76 FR 82299 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Data...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-30

    ... to ``Data Coordinating Center for Autism and Other Developmental Disabilities Research and... Control Special Emphasis Panel (SEP): Data Coordinating Center for Autism and Other Developmental Disabilities Research and Epidemiologic Studies, RFA DD12-001, Initial Review In accordance with Section...

  19. 76 FR 13621 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Family...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-14

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Family History and Diamond Blackfan Anemia, DD11- 010,...

  20. 75 FR 28261 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Improved...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-20

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Improved Diagnostics for Lyme Borreliosis, Funding Opportunity... Committee Act (Pub. L. 92-463), the Centers for Disease Control and Prevention (CDC) announces...

  1. 75 FR 28625 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Assessment...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-21

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Assessment of Post-Treatment Lyme Disease Syndrome, Funding...-Treatment Lyme Disease Syndrome,'' FOA CK10-004. Contact Person for More Information: Maurine Goodman,...

  2. 76 FR 15984 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Combining...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-22

    ... Control Special Emphasis Panel (SEP): Combining Subjective and Objective Methods for Quantifying Contact... applications received in response to ``Combining Subjective and Objective Methods for Quantifying Contact Rates and Mixing Pattern in School-Aged Children, FOA CK11-006.'' Contact Person For More...

  3. 76 FR 9785 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Human...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Human Immunodeficiency Virus (HIV) Prevention Projects for Young...

  4. 76 FR 27327 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Virologic...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Virologic Evaluation of the Modes of Influenza Virus...

  5. 78 FR 78966 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Initial Review The meeting announced below concerns Capacity Building Assistance for High Impact...

  6. 75 FR 29561 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Surveillance...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-26

    ... No: 2010-12627] DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Surveillance, Natural... Officer, National Center for Chronic Disease Prevention and Health Promotion, Office of the...

  7. 61 FR 58597 - Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1996-11-15

    ... From the Federal Register Online via the Government Publishing Office NATIONAL SCIENCE FOUNDATION Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting In accordance... submitted to NSF for financial support. Agenda: To review and evaluate Robotics and Machine...

  8. 61 FR 58597 - Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1996-11-15

    ... From the Federal Register Online via the Government Publishing Office NATIONAL SCIENCE FOUNDATION Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting In accordance with the Federal Advisory Committee Act (Pub. L. 92- 463, as amended), the National Science...

  9. 62 FR 19623 - Special Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1997-04-22

    ... [Federal Register Volume 62, Number 77 (Tuesday, April 22, 1997)] [Notices] [Page 19623] [FR Doc No: 97-10374] NATIONAL SCIENCE FOUNDATION Special Emphasis Panel in Information, Robotics and... Panel in Information, Robotics and Intelligent Systems (1200). Date and Time: May 5-6, 1997, 8:30...

  10. 64 FR 54368 - Special Emphasis Panel in Information, Robotics, and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1999-10-06

    ... From the Federal Register Online via the Government Publishing Office NATIONAL SCIENCE FOUNDATION Special Emphasis Panel in Information, Robotics, and Intelligent Systems; Notice of Meeting In accordance with the Federal Advisory Committee Act (Pub. L. 92- 463, as amended), the National Science...

  11. 76 FR 10908 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Maternal...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Maternal Vitamin D Status and Preterm Birth, DP11-002,...

  12. 76 FR 13621 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel; Teleconference

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-14

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel; Teleconference Disease, Disability, and Injury Prevention and Control... Centers for Disease Control and Prevention (CDC) announces the aforementioned meeting: Time and Date: 11...

  13. 75 FR 78998 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Addressing...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-17

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Addressing Global TB Prevention and Control in all Populations and Strengthening Health...

  14. 75 FR 28622 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Conducting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-21

    ... Control Special Emphasis Panel (SEP): Conducting Public Health Research in Kenya (U01)(Panel A), Funding..., discussion, and evaluation of applications received in response to ``Conducting Public Health Research in... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH...

  15. 76 FR 4911 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel: Occupational...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-27

    ... Control Special Emphasis Panel: Occupational Safety and Health Educational Research Centers, Program... Educational Research Centers, PAR 10-217.'' There were site visits conducted at the University of Cincinnati... Educational Research Centers, PAR 10-217. Contact Person for More Information: M. Chris Langub,...

  16. 75 FR 13769 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Natural...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-23

    ... HUMAN SERVICES Centers for Disease Control and Prevention Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Natural Experiments and Effectiveness Studies To Identify the Best..., discussion, and evaluation of ``Natural Experiments and Effectiveness Studies to Identify the Best Policy...

  17. 76 FR 367 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): Minority HIV...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-04

    ... Control Special Emphasis Panel (SEP): Minority HIV/AIDS Research Initiative (MARI) To Build Capacity in Black and Hispanic Communities and Among Black and Hispanic Researchers To Conduct HIV/AIDS... evaluation of applications received in response to ``Minority HIV/AIDS Research Initiative (MARI) to...

  18. 75 FR 38533 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-02

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis... Alcohol Abuse and Alcoholism, Office of Extramural Activities, Extramural Project Officer, 5635...

  19. 78 FR 65347 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-31

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis... Abuse and Alcoholism, 5635 Fishers Lane (Teleconference), Rockville, MD 20855. Contact Person:...

  20. 75 FR 10808 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-09

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis... Officer, National Institute on Alcohol Abuse & Alcoholism, National Institutes of Health, 5635...

  1. 75 FR 57473 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-21

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis... Officer, National Institute on Alcohol Abuse and Alcoholism, Office of Extramural Activities,...

  2. Child Abuse among Children with Disabilities: Implications for Special Educators.

    ERIC Educational Resources Information Center

    Pearson, Suzanne

    1996-01-01

    This discussion of child abuse in children with disabilities focuses on teachers' rights and responsibilities for reporting abuse and the need to overcome barriers to reporting abuse. Recommendations to protect teachers from unwarranted allegations of abuse are also given, including creating an open classroom environment, distinguishing between…

  3. Emotional Disturbance and Substance Abuse/Addiction Special Education Programming for the Dually-Diagnosed Adolescent.

    ERIC Educational Resources Information Center

    Bogdaniak, Roman C.

    Dually diagnosed adolescents suffering from both severe emotional disturbance and substance abuse/addiction constitute a special population which poses a challenge to health professionals in special education as well as clinical settings. The prevalence of substance use, abuse, and addiction has been shown to be significantly above the national…

  4. 77 FR 39713 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-05

    ... Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meetings Pursuant to section 10(d) of the... Alcohol Abuse and Alcoholism Special Emphasis Panel; Review of RFA AA-12-010. Date: July 18, 2012. Time: 1... Abuse and Alcoholism Special Emphasis Panel; NIAAA Member conflict SEP-- Neurosciences. Date: July...

  5. 77 FR 75179 - National Institute on Drug Abuse; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-19

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meetings... Committee: National Institute on Drug Abuse Special Emphasis Panel; N43DA13-4417: Video Gaming Targeting..., rogersn2@nida.nih.gov . Name of Committee: National Institute on Drug Abuse Special Emphasis Panel;...

  6. Special Considerations for Substance Abuse Intervention with Latino Youth

    ERIC Educational Resources Information Center

    Goldbach, Jeremy T.; Thompson, Sanna J.; Holleran Steiker, Lori K.

    2011-01-01

    Nearly 10% of Latino youth who are twelve and older are in need of substance abuse treatment for alcohol or illicit drug use. Ethnic differences exist with regard to susceptibility to drug use, attitudes regarding drugs, and drug resistance strategies. The failure of some substance abuse prevention programs can be traced in part to their lack of…

  7. Substance Abuse Prevention Education. Special Topic Curriculum Resources Packet.

    ERIC Educational Resources Information Center

    Connecticut State Dept. of Education, Hartford.

    This curriculum resources packet provides the most current information available in substance abuse prevention education. Its stated purpose is to assist schools in combating the problem of substance abuse through effective prevention/education programs. These topic areas are discussed: (1) drugs and their effects; (2) continuum of drug use; (3)…

  8. The liver in acquired immune deficiency syndrome: emphasis on patients with intravenous drug abuse.

    PubMed

    Dworkin, B M; Stahl, R E; Giardina, M A; Wormser, G P; Weiss, L; Jankowski, R; Rosenthal, W S

    1987-03-01

    To assess the spectrum of hepatic abnormalities in acquired immune deficiency syndrome (AIDS), we reviewed clinical, biochemical, and pathological material in 32 patients with AIDS. Eight-four percent of AIDS cases had a history of intravenous drug abuse. Ninety percent of AIDS patients has some liver biochemical abnormality at the first presentation of illness. During the course of AIDS, significant (p less than 0.05, paired Student's t test) rises in alkaline phosphatase and bilirubin occurred, without rises in aminotransferases. Mean abnormalities were mild, reflecting approximately 2-fold increases over baseline. Liver failure was not believed to contribute to the death of any AIDS patient. Pathological findings in AIDS included specific infectious diagnosis in 26%, granulomas in 16%, hemosiderosis in 26%, nonspecific abnormalities in 39%, cirrhosis in 23%, and chronic active hepatitis in 3%. AIDS cases were also compared to 10 selected age, sex, and epidemiologically similar non-AIDS patients. Although granulomas or infections were not seen in our comparison group, only the incidence of chronic active hepatitis was significantly different between the groups. If only those with intravenous drug abuse were studied, then none of 24 AIDS patients versus four of eight non-AIDS cases (p less than 0.005) had chronic active hepatitis. AIDS patients with specific hepatic infections tended to have a higher alkaline phosphatase and aspartate aminotransferase (p less than 0.05) than noninfected cases. However, substantial overlap existed, and no difference in hepatomegaly was noted. Ninety percent of AIDS patients were ingesting at least one potentially hepatotoxic drug. We conclude that AIDS patients have a high incidence of underlying hepatic abnormalities. However, clinical and biochemical abnormalities are similar in our selected liver biopsy patients with intravenous drug abuse with or without AIDS. As expected, AIDS patients have a higher incidence of hepatic

  9. Geostationary platform systems concepts definition follow-on study. Volume 2A: Technical Task 2 LSST special emphasis

    NASA Technical Reports Server (NTRS)

    1980-01-01

    The results of the Large Space Systems Technology special emphasis task are presented. The task was an analysis of structural requirements deriving from the initial Phase A Operational Geostationary Platform study.

  10. Pharmaceutical solvates, hydrates and amorphous forms: A special emphasis on cocrystals.

    PubMed

    Healy, Anne Marie; Worku, Zelalem Ayenew; Kumar, Dinesh; Madi, Atif M

    2017-03-22

    Active pharmaceutical ingredients (APIs) may exist in various solid forms, which can lead to differences in the intermolecular interactions, affecting the internal energy and enthalpy, and the degree of disorder, affecting the entropy. Differences in solid forms often lead to differences in thermodynamic parameters and physicochemical properties for example solubility, dissolution rate, stability and mechanical properties of APIs and excipients. Hence, solid forms of APIs play a vital role in drug discovery and development in the context of optimization of bioavailability, filing intellectual property rights and developing suitable manufacturing methods. In this review, the fundamental characteristics and trends observed for pharmaceutical hydrates, solvates and amorphous forms are presented, with special emphasis, due to their relative abundance, on pharmaceutical hydrates with single and two-component (i.e. cocrystal) host molecules.

  11. Pre-Service Special Education Teachers' Professionalism and Preparation in Terms of Child Sexual Abuse

    ERIC Educational Resources Information Center

    Al-Zboon, Eman; Ahmad, Jamal

    2016-01-01

    This study aimed at examining Jordanian pre-service special education teachers' professionalism and preparation on the topic of child sexual abuse (CSA). Qualitative research data from interviews with 20 pre-service special education teachers were analysed using thematic analysis. The results showed that these participants generally hold avoiding…

  12. 77 FR 59405 - National Institute On Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-27

    ... National Institute On Alcohol Abuse and Alcoholism; Notice of Closed Meeting Pursuant to section 10(d) of... Institute on Alcohol Abuse and Alcoholism Special Emphasis Panel; NIAAA AA-1 Member Conflict Applications...., Scientific Review Officer, National Institute [[Page 59406

  13. 78 FR 38353 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-26

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis Panel; Review of Applications on HIV- AIDS/Alcohol Comparative Effectiveness & Implementation...

  14. Numerical investigation of three-dimensional cloud cavitation with special emphasis on collapse induced shock dynamics

    NASA Astrophysics Data System (ADS)

    Schnerr, Günter H.; Sezal, Ismail H.; Schmidt, Steffen J.

    2008-04-01

    The aim of the present investigation is to model and analyze compressible three-dimensional (3D) cavitating liquid flows with special emphasis on the detection of shock formation and propagation. We recently developed the conservative finite volume method CATUM (Cavitation Technische Universität München), which enables us to simulate unsteady 3D liquid flows with phase transition at all Mach numbers. The compressible formulation of the governing equations together with the thermodynamic closure relations are solved by a modified Riemann approach by using time steps down to nanoseconds. This high temporal resolution is necessary to resolve the wave dynamics that leads to acoustic cavitation as well as to detect regions of instantaneous high pressure loads. The proposed two-phase model based on the integral average properties of thermodynamic quantities is first validated against the solution of the Rayleigh-Plesset equation for the collapse of a single bubble. The computational fluid dynamics tool CATUM is then applied to the numerical simulation of the highly unsteady two-phase flow around a 3D twisted hydrofoil. This specific hydrofoil allows a detailed study of sheet and cloud cavitation structures related to 3D shock dynamics emerging from collapsing vapor regions. The time dependent development of vapor clouds, their shedding mechanism, and the resulting unsteady variation of lift and drag are discussed in detail. We identify instantaneous local pressure peaks of the order of 100bar, which are thought to be responsible for the erosive damage of the surface of the hydrofoil.

  15. Comparative assessment of metallurgical recovery of metals from electronic waste with special emphasis on bioleaching.

    PubMed

    Priya, Anshu; Hait, Subrata

    2017-01-14

    Waste electrical and electronic equipment (WEEE) or electronic waste (e-waste) is one of the fastest growing waste streams in the urban environment worldwide. The core component of printed circuit board (PCB) in e-waste contains a complex array of metals in rich quantity, some of which are toxic to the environment and all of which are valuable resources. Therefore, the recycling of e-waste is an important aspect not only from the point of waste treatment but also from the recovery of metals for economic growth. Conventional approaches for recovery of metals from e-waste, viz. pyrometallurgical and hydrometallurgical techniques, are rapid and efficient, but cause secondary pollution and economically unviable. Limitations of the conventional techniques have led to a shift towards biometallurgical technique involving microbiological leaching of metals from e-waste in eco-friendly manner. However, optimization of certain biotic and abiotic factors such as microbial species, pH, temperature, nutrients, and aeration rate affect the bioleaching process and can lead to profitable recovery of metals from e-waste. The present review provides a comprehensive assessment on the metallurgical techniques for recovery of metals from e-waste with special emphasis on bioleaching process and the associated factors.

  16. Molecular phylogeny of rodents, with special emphasis on murids: evidence from nuclear gene LCAT.

    PubMed

    Robinson, M; Catzeflis, F; Briolay, J; Mouchiroud, D

    1997-12-01

    Phylogenetic relationships among 19 extant species of rodents, with special emphasis on rats, mice, and allied Muroidea, were studied using sequences of the nuclear protein-coding gene LCAT (lecithin:cholesterol acyltransferase), an enzyme of cholesterol metabolism. Analysis of 705 base pairs from the exonic regions of LCAT confirmed known groupings in and around Muroidea. Strong support was found for the families Sciuridae (squirrel and marmot) and Gliridae (dormice) and for suprafamilial taxa Muroidea and Caviomorpha (guinea pig and allies). Within Muroidea, the first branching leads to the fossorial mole rats Spalacinae and bamboo rats Rhizomyinae. The other Muroidea appear as a polytomy from which are issued Gerbillinae (gerbils), Murinae (rats and mice), Sigmodontinae (New World cricetids), Cricetinae (hamsters), and Arvicolinae (voles). Evidence from LCAT sequences agrees with that from a number of previous molecular and morphological studies, both concerning branching orders inside Muroidea and the bush-like radiation of rodent suprafamilial taxa (caviomorphs, sciurids, glirids, muroids), thus suggesting that this nuclear gene is an appropriate candidate for addressing questions of rodents relationships.

  17. 75 FR 13560 - Disease, Disability, and Injury Prevention and Control Special Emphasis Panel (SEP): RFA DD 10...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-22

    ... Control Special Emphasis Panel (SEP): RFA DD 10-002 Public Health Research on Spina Bifida, RFA DD 10-003 Public Health Research on Children and Adults Living With Spina Bifida, RFA DD 10-004 Developing a... Health Research on Spina Bifida, RFA DD 10-003 Public Health Research on Children and Adults Living...

  18. Drug Abuse Treatment: The Halfway House and Other Specially Supervised Modalities.

    ERIC Educational Resources Information Center

    Peck, David

    This research deals primarily with an overview of drug use and/or abuse, with specific discussion of the halfway house concept of treatment, including definition, historical framework, rationales, and inherent problems of halfway houses as modalities of treatment (i.e., economics of the treatment modality). Other special treatment modalities are…

  19. Determination of lactic acid with special emphasis on biosensing methods: A review.

    PubMed

    Pundir, Chandra S; Narwal, Vinay; Batra, Bhawna

    2016-12-15

    Lactic acid (2-Hydroxypropanoic acid) is generated from pyruvic acid under anaerobic condition in skeletal muscles, brain, red blood cells, and kidney. Lactate in normal human subjects get cleared very quickly at a rate of 320mmol/L/hr, mostly by liver metabolism and re-conversion of lactate back to pyruvate. Measurement of lactate level in serum is required for the differential diagnosis and medical management of hyperlactatemia, cardiac arrest and resuscitation, sepsis, reduced renal excretion, hypoxia induced cancer, decreased extra hepatic metabolism, intestinal infarction and lactic acidosis. Determination of lactate is also important in dairy products and beverages to access their quality. Among the various methods available for detection of lactate, most are complicated, nonspecific, less sensitive and require time-consuming sample pretreatment, expensive instrumental set-up and trained persons to operate, specifically for chromatographic methods. Biosensing methods overcome these drawbacks, as these are simple, fast, specific and highly sensitive. Lactate biosensors reported so far, work optimally within 3-180s, between pH, 5.5-8.5 and temperature 22°C to 37°C and lactate concentration ranging from 10 to 2000µM. These biosensors have been employed to measure lactate level in embryonic cell culture, beverages, urine, and serum samples and reused upto 200-times within a period of 7-216 days. This review presents the principles, merits and demerits of various analytical methods for lactate determination with special emphasis on lactate biosensors. The future perspective for improvement of analytic performance of lactate biosensors are discussed.

  20. 75 FR 3239 - National Institute on Drug Abuse; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-20

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meeting... Committee: National Institute on Drug Abuse Special Emphasis Panel; Rapid Assessment for Drug Abuse and... Affairs, National Institute on Drug Abuse, NIH, DHHS, Room 220, MSC 8401, 6101 Executive...

  1. 75 FR 14175 - National Institute on Drug Abuse; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-24

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meeting... Committee: National Institute on Drug Abuse Special Emphasis Panel; Substance Abuse Treatment Referral..., National Institute on Drug Abuse, NIH, DHHS, Room 220, MSC 8401, 6101 Executive Boulevard, Bethesda,...

  2. 77 FR 63846 - National Institute on Drug Abuse; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-17

    ... Special Emphasis Panel; Synthesis and Preclinical Evaluation of Medications to Treat Substance Use... Special Emphasis Panel; The ] Diversity-promoting Institutions Drug Abuse Research Program (DIDARP). Date... Program Nos.: 93.279, Drug Abuse and Addiction Research Programs, National Institutes of Health,...

  3. Abuse

    MedlinePlus

    ... member, a trusted teacher, a doctor, or a school or religious youth counselor. Many teachers and counselors have training in how to recognize and report abuse. Telephone and online directories list local child abuse and family violence hotline numbers that you can call for help. ...

  4. Folk Remedies and Child Abuse: A Review with Emphasis on Caida de Mollera and Its Relationship to Shaken Baby Syndrome.

    ERIC Educational Resources Information Center

    Hansen, Karen Kirhofer

    1998-01-01

    Reviews a variety of folk remedies such as coining (Southeast Asia), cupping (primarily Russia), and moxibustion (Asia), which may be confused with child abuse. It especially considers the Hispanic folk illness "caida de mollera" (fallen fontanelle) but rejects the idea in the literature that folk treatment can cause the injuries seen in…

  5. Applying Continuous Quality Improvement Principles in Secondary School Vocational Education, with Emphasis on Special Populations.

    ERIC Educational Resources Information Center

    McLean, Gary N.

    1993-01-01

    Principles of quality management applicable to education for secondary special populations include process orientation, cascading, top commitment, vertical/horizontal communication, continuous improvement, shared vision, primacy of customers, investment in people, constancy of purpose, and shared goal setting. (JOW)

  6. Abuse

    MedlinePlus

    ... people to control their actions. Certain types of personality disorders or mental illness might also interfere with ... self-control. Of course, not everyone with a personality disorder or mental illness becomes abusive. Fortunately, people ...

  7. Abuse

    MedlinePlus

    ... Stages Early-Stage Caregiving Middle-Stage Caregiving Late-Stage Caregiving Behaviors Aggression & Anger Anxiety & Agitation Depression Hallucinations Memory Loss & Confusion Repetition Sleep Issues & Sundowning Suspicion & Delusions Wandering Abuse Start Here ...

  8. Recreational drugs of abuse.

    PubMed

    Albertson, Timothy E

    2014-02-01

    The use of recreational drugs of abuse continues to expand without limitations to national boundaries, social status, race, or education. Beyond the prevalence of illicit drug use and dependence, their contribution to the global burden of disease and death are large and troubling. All medical providers should be aware of the evolving drugs of abuse and their medical and social consequences. In addition to heroin and stimulants such as cocaine and methamphetamine, new designer stimulants called "bath salts" and cannabinoids called "spice," along with the abuse of prescription drugs and volatile substances, are now widely recognized problems in many societies. The wide variety and continuingly expanding clinical manifestations of toxicity of recreational drugs of abuse is not widely appreciated by clinicians. This edition attempts to summarize six major classes of drugs of abuse and their clinical effects with special emphasis on their immunological and respiratory effects.

  9. Planning and Implementing Career Education for the Special Student, with Emphasis on the Leisure Occupations.

    ERIC Educational Resources Information Center

    Vinton, Dennis A.; And Others

    A program of career education for exceptional students in the leisure occupations is described. It is explained that the book is designed for regular and special class teachers. Chapters one and two present information on career education principles and implementation. Chapters three through five deal with practical teaching concerns. Behavioral…

  10. Perspectives on Research in Alcohol and Drug Abuse As It Relates to Special Education and Personnel Preparation.

    ERIC Educational Resources Information Center

    Crow, Robert E.

    This paper reports on group discussion by 11 leaders in special education and related disciplines on research in alcohol and drug abuse, in relationship to the preparation of special education personnel. Five main themes emerged from the discussion: (1) prevention and drug education must be put into high gears; (2) systems change efforts,…

  11. Biosynthesis of GPI-anchored proteins: special emphasis on GPI lipid remodeling

    PubMed Central

    Kinoshita, Taroh; Fujita, Morihisa

    2016-01-01

    Glycosylphosphatidylinositols (GPIs) act as membrane anchors of many eukaryotic cell surface proteins. GPIs in various organisms have a common backbone consisting of ethanolamine phosphate (EtNP), three mannoses (Mans), one non-N-acetylated glucosamine, and inositol phospholipid, whose structure is EtNP-6Manα-2Manα-6Manα-4GlNα-6myoinositol-P-lipid. The lipid part is either phosphatidylinositol of diacyl or 1-alkyl-2-acyl form, or inositol phosphoceramide. GPIs are attached to proteins via an amide bond between the C-terminal carboxyl group and an amino group of EtNP. Fatty chains of inositol phospholipids are inserted into the outer leaflet of the plasma membrane. More than 150 different human proteins are GPI anchored, whose functions include enzymes, adhesion molecules, receptors, protease inhibitors, transcytotic transporters, and complement regulators. GPI modification imparts proteins with unique characteristics, such as association with membrane microdomains or rafts, transient homodimerization, release from the membrane by cleavage in the GPI moiety, and apical sorting in polarized cells. GPI anchoring is essential for mammalian embryogenesis, development, neurogenesis, fertilization, and immune system. Mutations in genes involved in remodeling of the GPI lipid moiety cause human diseases characterized by neurological abnormalities. Yeast Saccharomyces cerevisiae has >60 GPI-anchored proteins (GPI-APs). GPI is essential for growth of yeast. In this review, we discuss biosynthesis of GPI-APs in mammalian cells and yeast with emphasis on the lipid moiety. PMID:26563290

  12. 75 FR 76474 - National Institute on Drug Abuse; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-12-08

    ... Emphasis Panel Confirming Compliance with Experimental Pharmacotherapy Treatment of Drug Abuse (2225). Date... Antibodies or Vaccines for the Treatment of Substance Use Disorders (8898). Date: January 11, 2011. Time: 1 p...: National Institute on Drug Abuse Special Emphasis Panel Improving Measures of Addiction Risk (5562)....

  13. Embryonic oxidative stress as a mechanism of teratogenesis with special emphasis on diabetic embryopathy.

    PubMed

    Ornoy, Asher

    2007-07-01

    Reactive oxygen species (ROS) are involved in the etiology of numerous diseases including cardio-vascular diseases and diabetes mellitus. There is evidence that several teratogens affect the developing embryo by increasing its oxidative stress and, because of its relatively weak antioxidant defense, especially at the early stages of organogenesis, result in severe embryonic damage. This mechanism seems to operate in diabetes-induced embryonic damage as well as in the mechanism of teratogenicity caused by ionizing radiation, hypoxia, alcohol and cocaine use and cigarette smoking. We studied the role of oxidative stress in diabetic induced embryopathy, both in vivo and in vitro. Under diabetic condition there was a significant decrease in the activity of endogenous antioxidant enzymes and of vitamins C and E in the embryos and their yolk sacs. The lowest activity was observed in the malformed experimental embryos when compared to experimental embryos without anomalies. Similar results were obtained in the Cohen diabetic rats, where the diabetic prone (CDs) rats were unable to increase their antioxidant enzyme activity in spite of the diabetes. Studies performed by other investigators show similar results. Human and animal studies show that the main mechanism of fetal damage induced by high levels of ionizing irradiation, cocaine and alcohol abuse, hypoxia and cigarette smoking is also by increased embryonic oxidative stress. Similarly, several drugs exert their teratogenic activity via embryonic oxidative stress. Abnormal placentation may also cause enhanced placental oxidative stress, resulting in embryonic death, preeclampsia or congenital anomalies. Inability of the developing embryo to cope with that stress may result in embryonic death and/or congenital anomalies. Animal studies also show that a variety of antioxidants are effective in decreasing the damaging effects of heightened oxidative stress induced by teratogens. Effective antioxidants, which might also

  14. Neuroanatomical dichotomy of sexual behaviors in rodents: a special emphasis on brain serotonin

    PubMed Central

    Angoa-Pérez, Mariana; Kuhn, Donald M.

    2016-01-01

    sexual behavior and the participation of the serotonin system in the modulation of these behaviors with emphasis on rodents. PMID:26110223

  15. The brain-pituitary-gonad axis in male teleosts, with special emphasis on flatfish (Pleuronectiformes).

    PubMed

    Weltzien, Finn-Arne; Andersson, Eva; Andersen, Øivind; Shalchian-Tabrizi, Kamran; Norberg, Birgitta

    2004-03-01

    The key component regulating vertebrate puberty and sexual maturation is the endocrine system primarily effectuated along the brain-pituitary-gonad (BPG) axis. By far most investigations on the teleost BPG axis have been performed on salmonids, carps, catfish and eels. Accordingly, earlier reviews on the BPG axis in teleosts have focused on these species, and mainly on females (e.g. 'Fish Physiology, vol. IXA. Reproduction (1983) pp. 97'; 'Proceedings of the Fourth International Symposium on the Reproductive Physiology of Fish. FishSymp91, Sheffield, UK, 1991, pp. 2'; 'Curr. Top. Dev. Biol. 30 (1995) pp. 103'; 'Rev. Fish Biol. Fish. 7 (1997) pp. 173'; 'Proceedings of the Sixth International Symposium on the Reproductive Physiology of Fish. John Grieg A/S, Bergen, Norway, 2000, pp. 211'). However, in recent years new data have emerged on the BPG axis in flatfish, especially at the level of the brain and pituitary. The evolutionarily advanced flatfishes are important model species both from an evolutionary point of view and also because many are candidates for aquaculture. The scope of this paper is to review the present status on the male teleost BPG axis, with an emphasis on flatfish. In doing so, we will first discuss the present understanding of the individual constituents of the axis in the best studied teleost models, and thereafter discuss available data on flatfish. Of the three constituents of the BPG axis, we will focus especially on the pituitary and gonadotropins. In addition to reviewing recent information on flatfish, we present some entirely new information on the phylogeny and molecular structure of teleost gonadotropins.

  16. Domestic Violence and Child Abuse: A Selective Bibliography. Bibliography Series Eight.

    ERIC Educational Resources Information Center

    Brady, Mary Louise, Comp.

    This selective bibliography contains information on material dealing with domestic violence in the home with a special emphasis on child abuse, that may be obtained in the Robert E. Kennedy Library at California Polytechnic University. The bibliography is divided according to different forms of abuse, e.g., emotional child abuse, incest/sexual…

  17. 76 FR 51381 - National Institute on Drug Abuse; Notice of Closed Meetings

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    2011-08-18

    ....gov . (Catalogue of Federal Domestic Assistance Program Nos.: 93.279, Drug Abuse and Addiction... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meetings... Committee: National Institute on Drug Abuse Special Emphasis Panel SEDAPA R25. Date: September 22,...

  18. 78 FR 43890 - National Institute on Drug Abuse; Notice of Closed Meeting

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    2013-07-22

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  19. 78 FR 69858 - National Institute on Drug Abuse; Notice of Closed Meetings

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    2013-11-21

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  20. 77 FR 44640 - National Institute on Drug Abuse; Notice of Closed Meeting

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    2012-07-30

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  1. 76 FR 59414 - National Institute on Drug Abuse; Notice of Closed Meetings

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    2011-09-26

    ... . (Catalogue of Federal Domestic Assistance Program Nos.: 93.279, Drug Abuse and Addiction Research Programs... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meetings... Committee: National Institute on Drug Abuse Special Emphasis Panel, I/START Review Committee. Date:...

  2. 78 FR 6122 - National Institute on Drug Abuse; Notice of Closed Meetings

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    2013-01-29

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  3. 75 FR 80511 - National Institute on Drug Abuse; Notice of Closed Meetings

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  4. 78 FR 23772 - National Institute on Drug Abuse; Notice of Closed Meetings

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    2013-04-22

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  5. 75 FR 10807 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

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    2010-03-09

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  6. 76 FR 17140 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

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  7. 76 FR 15989 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

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    2011-03-22

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  8. 76 FR 2129 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

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    2011-01-12

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  9. 75 FR 64733 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

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    2010-10-20

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  10. 78 FR 55088 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

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  11. 77 FR 43603 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

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    2012-07-25

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis... Alcohol Abuse and Alcoholism, National Institutes of Health, 5635 Fishers Lane, Room 2081, Rockville,...

  12. 77 FR 43098 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

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    2012-07-23

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis...., Scientific Review Officer, National Institute on Alcohol Abuse and Alcoholism, 5635 Fishers Lane, Room...

  13. 75 FR 53320 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

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    2010-08-31

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism, Special Emphasis... Review Officer, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health,...

  14. 75 FR 42451 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

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    2010-07-21

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism, Special Emphasis... Review Officer, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health,...

  15. 76 FR 26311 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

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    2011-05-06

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis... on Alcohol Abuse and Alcoholism, 5635 Fishers Lane, Room 2109, Rockville, MD 20852,...

  16. 76 FR 34718 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

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    2011-06-14

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis... Institute on Alcohol Abuse and Alcoholism, 5635 Fishers Lane, Room 2109, Rockville, MD 20852,...

  17. 77 FR 2304 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

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    2012-01-17

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism; Special Emphasis..., Ph.D., Scientific Review Officer, National Institute on Alcohol Abuse and Alcoholism,...

  18. 75 FR 9421 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

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    2010-03-02

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis..., National Institute on Alcohol Abuse & Alcoholism, 5635 Fishers Lane, Room 2085, Rockville, MD...

  19. 76 FR 34719 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

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    2011-06-14

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis... on Alcohol Abuse and Alcoholism, 5635 Fishers Lane, Room 2109, Rockville, MD 20852,...

  20. 75 FR 16815 - National Institute on Drug Abuse; Notice of Closed Meeting

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    2010-04-02

    ..., Drug Abuse and Addiction Research Programs, National Institutes of Health, HHS) ] Dated: March 24, 2010... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meeting... of Committee: National Institute on Drug Abuse Special Emphasis Panel; N44DA-10-5541:...

  1. 76 FR 22715 - National Institute on Drug Abuse; Notice of Closed Meeting

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    2011-04-22

    ... Committee: National Institute on Drug Abuse Special Emphasis Panel; NIDA Blending Research and Practice..., Drug Abuse and Addiction Research Programs, National Institutes of Health, HHS) Dated: April 15, 2011... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed...

  2. 75 FR 16815 - National Institute on Drug Abuse; Notice of Closed Meeting

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    2010-04-02

    ... cycle. (Catalogue of Federal Domestic Assistance Program Nos. 93.279, Drug Abuse and Addiction Research... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meeting... Committee: National Institute on Drug Abuse Special Emphasis Panel; Mechanism for Time-Sensitive Drug...

  3. 78 FR 22892 - National Institute on Drug Abuse; Notice of Closed Meeting

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    2013-04-17

    ....: 93.279, Drug Abuse and Addiction Research Programs, National Institutes of Health, HHS) Dated: April... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meeting... Committee: National Institute on Drug Abuse Special Emphasis Panel, Feedback-regulated Naloxone...

  4. 75 FR 80512 - National Institute on Drug Abuse; Notice of Closed Meetings

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    2010-12-22

    ... Committee: National Institute on Drug Abuse Special Emphasis Panel; NIDA Cutting-Edge Basic Research Award....: 93.279, Drug Abuse and Addiction Research Programs, National Institutes of Health, HHS) Dated... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed...

  5. 78 FR 13362 - National Institute on Drug Abuse; Notice of Closed Meeting

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    2013-02-27

    ... funding cycle. (Catalogue of Federal Domestic Assistance Program Nos.: 93.279, Drug Abuse and Addiction... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meeting... Committee: National Institute on Drug Abuse Special Emphasis Panel; NIH Pathway to Independence...

  6. 76 FR 59415 - National Institute on Drug Abuse; Notice of Closed Meeting

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    2011-09-26

    .... (Catalogue of Federal Domestic Assistance Program Nos.: 93.279, Drug Abuse and Addiction Research Programs... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meeting... Committee: National Institute on Drug Abuse Special Emphasis Panel, Multisites Applications (R01)...

  7. 77 FR 72366 - National Institute on Drug Abuse; Notice of Closed Meetings

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    2012-12-05

    ... funding cycle. Name of Committee: National Institute on Drug Abuse Special Emphasis Panel; Cognitive... review and funding cycle. (Catalogue of Federal Domestic Assistance Program Nos.: 93.279, Drug Abuse and... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed...

  8. 75 FR 71712 - National Institute on Drug Abuse; Notice of Closed Meeting

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    2010-11-24

    ... Committee: National Institute on Drug Abuse Special Emphasis Panel; NIDA Cutting-Edge Basic Research Awards... Federal Domestic Assistance Program Nos.: 93.279, Drug Abuse and Addiction Research Programs, National... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed...

  9. 76 FR 31967 - National Institute On Drug Abuse; Notice of Closed Meetings

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    2011-06-02

    ... Federal Domestic Assistance Program Nos.: 93.279, Drug Abuse and Addiction Research Programs, National... HUMAN SERVICES National Institutes of Health National Institute On Drug Abuse; Notice of Closed Meetings... Committee: National Institute on Drug Abuse Special Emphasis Panel; NIDA R13 Conference Grant Review....

  10. 77 FR 33477 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

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    2012-06-06

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis... Institutes of Health National Institute on Alcohol Abuse and Alcoholism, 5635 Fishers Lane, Rm 2017,...

  11. 76 FR 50743 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

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    2011-08-16

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis... Institute on Alcohol Abuse and Alcoholism, 5635 Fishers Lane, Room 2109, Rockville, MD 20852,...

  12. 75 FR 71711 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

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    2010-11-24

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis..., EPRB, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, 5635...

  13. 78 FR 66015 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

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    2013-11-04

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis.... Agenda: To review and evaluate grant applications Place: National Institute on Alcohol Abuse...

  14. 76 FR 59709 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

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    2011-09-27

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis... Officer, National Institute on Alcohol Abuse and Alcoholism, 5635 Fishers Lane, Room 2109, Rockville,...

  15. 77 FR 27075 - National Institute on Drug Abuse Notice of Closed Meeting

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    2012-05-08

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse Notice of Closed Meeting... Committee: National Institute on Drug Abuse Special Emphasis Panel; Regulatory Affairs Support (8902). Date... Affairs, National Institute on Drug Abuse, NIH, DHHS, Room 4227, MSC 9550, 6001 Executive...

  16. 75 FR 21006 - National Institute on Drug Abuse; Notice of Closed Meeting

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    2010-04-22

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meeting... Committee: National Institute on Drug Abuse Special Emphasis Panel; R25 Review (PAR-07-221). Date: April 29... Institute on Drug Abuse, NIH, 6101 Executive Blvd., Rm. 213, MSC 8401, Bethesda, MD 20892,...

  17. 75 FR 63491 - National Institute on Drug Abuse; Notice of Closed Meetings

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    2010-10-15

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meetings... Committee: National Institute on Drug Abuse Special Emphasis Panel, NIDA Basic Science Conference Grant (R13..., National Institute on Drug Abuse, NIH, DHHS, Room 220, MSC 8401, 6101 Executive, Blvd., Bethesda, MD...

  18. 75 FR 42104 - National Institute on Drug Abuse; Notice of Closed Meeting

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    2010-07-20

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meeting... Committee: National Institute on Drug Abuse Special Emphasis Panel Systems Biology, HIV/AIDS, and Substance..., National Institute on Drug Abuse, NIH, DHHS, Room 220, MSC 8401, 6101 Executive Boulevard, Bethesda,...

  19. 77 FR 22581 - National Institute on Drug Abuse; Notice of Closed Meeting

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    2012-04-16

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meeting... Committee: National Institute on Drug Abuse Special Emphasis Panel Multi-site Trials. Date: May 22, 2012... Affairs, National Institute on Drug Abuse, NIH, DHHS, 6001 Executive Blvd., Room 4226, MSC 9550,...

  20. 76 FR 31968 - National Institute on Drug Abuse; Notice of Closed Meeting

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    2011-06-02

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meeting... Committee: National Institute on Drug Abuse Special Emphasis Panel; Technical Conference Support for DPMCDA... Affairs, National Institute on Drug Abuse, NIH, DHHS, Room 4227, MSC 9550, 6001 Executive...

  1. 78 FR 25460 - National Institute on Drug Abuse; Notice of Closed Meetings

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    2013-05-01

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meetings... Committee: National Institute on Drug Abuse Special Emphasis Panel; NIDA I/START Small Grant Review. Date... Affairs, National Institute on Drug Abuse, NIH, DHHS, 6001 Executive Blvd., Room 4238, MSC 9550,...

  2. 77 FR 22579 - National Institute on Drug Abuse; Notice of Closed Meetings

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    2012-04-16

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meetings... Committee: National Institute on Drug Abuse Special Emphasis Panel E-Technology Tools for Extending the... Institute on Drug Abuse, NIH, DHHS, 6001 Executive Blvd., Room 4229, MSC 9550, Bethesda, MD 20892-9550,...

  3. 76 FR 65517 - National Institute on Drug Abuse Notice of Closed Meetings

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    2011-10-21

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse Notice of Closed Meetings... Committee: National Institute on Drug Abuse Special Emphasis Panel, NIDA R13 Conference Grant Review. Date... Affairs, National Institute on Drug Abuse, NIH, 6001 Executive Blvd., Room 4226, MSC 9550, Bethesda,...

  4. 78 FR 19499 - National Institute on Drug Abuse; Notice of Closed Meeting

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    2013-04-01

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meeting... Committee: National Institute on Drug Abuse Special Emphasis Panel; Profile Screening and Predictive..., Office of Extramural Affairs, National Institute on Drug Abuse, NIH, DHHS, Room 4227, MSC 9550,...

  5. 76 FR 35227 - National Institute on Drug Abuse; Notice of Closed Meeting

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    2011-06-16

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meeting... Committee: National Institute on Drug Abuse Special Emphasis Panel, SecuRX: Preventing Prescription Drug..., Office of Extramural Affairs, National Institute on Drug Abuse, NIH, Room 4228, MSC 9550, ]...

  6. 77 FR 75179 - National Institute on Drug Abuse Notice of Closed Meetings

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    2012-12-19

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse Notice of Closed Meetings... of Committee: National Institute on Drug Abuse Special Emphasis Panel; Collaborative Clinical Trials..., Office of Extramural Affairs, National Institute on Drug Abuse, NIH, Room 4228, MSC 9550, 6001...

  7. 78 FR 40755 - National Institute on Drug Abuse; Notice of Closed Meeting

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    2013-07-08

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meeting... Committee: National Institute on Drug Abuse Special Emphasis Panel; NIH Summer Research Experience Programs... Officer, Office of Extramural Affairs, National Institute on Drug Abuse, NIH, DHHS, Room 4245, MSC...

  8. 75 FR 9606 - National Institute on Drug Abuse; Notice of Closed Meeting

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    2010-03-03

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meeting... Committee: National Institute on Drug Abuse Special Emphasis Panel; Web-Enabled Cognitive/Neuropsychological... Affairs, National Institute on Drug Abuse, NIH, DHHS, Room 220, MSC 8401, 6101 Executive...

  9. 77 FR 33472 - National Institute on Drug Abuse; Notice of Closed Meetings

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    2012-06-06

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meetings... Committee: National Institute on Drug Abuse Special Emphasis Panel Training and Career Development... Administrator, Office of Extramural Affairs, National Institute on Drug Abuse, NIH, DHHS, Room 4245, MSC...

  10. 76 FR 3916 - National Institute on Drug Abuse; Notice of Closed Meetings

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    2011-01-21

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meetings... Committee: National Institute on Drug Abuse Special Emphasis Panel; NIDA B/START R03 Small Grant Review... Affairs, National Institute on Drug Abuse, NIH, DHHS, Room 4238, MSC 9550, 6001 Executive Blvd.,...

  11. 76 FR 35226 - National Institute on Drug Abuse; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-16

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  12. 76 FR 81954 - National Institute on Drug Abuse; Notice of Closed Meeting

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  13. 75 FR 13136 - National Institute on Drug Abuse; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

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  14. 78 FR 64960 - National Institute on Drug Abuse; Notice of Closed Meetings

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  15. 75 FR 6042 - National Institute on Drug Abuse; Notice of Closed Meeting

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  16. 77 FR 47654 - National Institute on Drug Abuse; Notice of Closed Meetings

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    2012-08-09

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  17. 78 FR 19499 - National Institute on Drug Abuse; Notice of Closed Meeting

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    2013-04-01

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meeting... Committee: National Institute on Drug Abuse Special Emphasis Panel PAR-12-297: Mechanism for Time-Sensitive Drug Abuse Research. Date: April 9, 2013. Time: 12:00 p.m. to 2:00 p.m. Agenda: To review and...

  18. 77 FR 69640 - National Institute on Drug Abuse; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-20

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  19. 77 FR 3480 - National Institute on Drug Abuse, Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

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  20. 78 FR 27411 - National Institute on Drug Abuse Notice of Closed Meetings

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  1. 76 FR 81952 - National Institute on Drug Abuse; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-29

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  2. 77 FR 27075 - National Institute on Drug Abuse; Notice of Closed Meetings

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    2012-05-08

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  3. 77 FR 47654 - National Institute on Drug Abuse; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-09

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meeting... Committee: National Institute on Drug Abuse Special Emphasis Panel Clinical Trials Research Coordination... of Extramural Affairs, National Institute on Drug Abuse, NIH, DHHS, Room 4227, MSC 9550,...

  4. 78 FR 37835 - National Institute on Drug Abuse; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-24

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  5. 78 FR 63995 - National Institute on Drug Abuse; Notice of Closed Meeting

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    2013-10-25

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  6. 75 FR 42102 - National Institute on Drug Abuse; Notice of Closed Meeting

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    2010-07-20

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  7. 75 FR 9420 - National Institute on Drug Abuse; Notice of Closed Meeting

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    2010-03-02

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  8. 78 FR 9065 - National Institute on Drug Abuse; Notice of Closed Meeting

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    2013-02-07

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meeting... Committee: National Institute on Drug Abuse Special Emphasis Panel; The Diversity-promoting Institutions Drug Abuse Research Program (DIDARP). Date: March 26, 2013. ] Time: 1:00 p.m. to 4:00 p.m. Agenda:...

  9. 78 FR 27410 - National Institute on Drug Abuse; Notice of Closed Meeting

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    2013-05-10

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  10. 78 FR 56238 - National Institute on Drug Abuse; Notice of Closed Meetings

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    2013-09-12

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meetings... Committee: National Institute on Drug Abuse Special Emphasis Panel Multisite Clinical Trials. Date... Extramural Affairs, National Institute on Drug Abuse, NIH, DHHS, Room 4234, MSC 9550, 6001 Executive...

  11. Satellite Power Systems (SPS) concept definition study, exhibit C. Volume 5: Special emphasis studies

    NASA Technical Reports Server (NTRS)

    Hanley, G.

    1979-01-01

    Specific areas were analyzed and identified as high priority for more in-depth analysis. These areas were: (1) rectenna constructability; (2) satellite constructability; (3) support systems constructability; (4) space environmental analysis, and (5) special end-to-end analyses. Baseline requirements specified coplanar solar blankets and an end mounted antenna, utilizing either GaAlAs solar cells and employing a CR of 2, or Si cells. Several configurations were analyzed. Utilizing the preferred configuration as a baseline, a satellite construction base was defined, precursor operations incident to establishment of orbital support facilities identified, and the satellite construction sequence and procedures developed. Since the baseline specifies sixty instead of one hundred and twenty satellites to be constructed in a thirty year period, mass flow to orbit requirements were revised and new traffic models established. Launch site requirements (exclusive of actual launch operations) in terms of manpower and building space were defined.

  12. Advanced system identification techniques for wind turbine structures with special emphasis on modal parameters

    NASA Astrophysics Data System (ADS)

    Bialasiewicz, J. T.

    1995-06-01

    The goal is to develop advanced system identification techniques that can be used to accurately measure the frequency response functions of a wind-turbine structure immersed in wind noise. To allow for accurate identification, the authors have developed a special test signal called the pseudo-random binary sequence (PRBS). The Matlab program that generates this signal allows the user to interactively tailor its parameters for the frequency range of interest based on the response of the wind turbine under test. By controlling NREL's Mobile Hydraulic Shaker System, which is attached to the wind turbine structure, the PRBS signal produces the wide-band excitation necessary to perform system identification in the presence of wind noise. The techniques presented here will enable researchers to obtain modal parameters from an operating wind turbine, including frequencies, damping coefficients, and mode shapes. More importantly, the algorithms they have developed and tested (so far using input-output data from a simulated structure) permit state-space representation of the system under test, particularly the modal state space representation. This is the only system description that reveals the internal behavior of the system, such as the interaction between the physical parameters, and which, in contrast to transfer functions, is valid for non-zero initial conditions.

  13. The Role of MicroRNAs in Diabetic Complications-Special Emphasis on Wound Healing.

    PubMed

    Moura, João; Børsheim, Elisabet; Carvalho, Eugenia

    2014-09-29

    Overweight and obesity are major problems in today's society, driving the prevalence of diabetes and its related complications. It is important to understand the molecular mechanisms underlying the chronic complications in diabetes in order to develop better therapeutic approaches for these conditions. Some of the most important complications include macrovascular abnormalities, e.g., heart disease and atherosclerosis, and microvascular abnormalities, e.g., retinopathy, nephropathy and neuropathy, in particular diabetic foot ulceration. The highly conserved endogenous small non-coding RNA molecules, the micro RNAs (miRNAs) have in recent years been found to be involved in a number of biological processes, including the pathogenesis of disease. Their main function is to regulate post-transcriptional gene expression by binding to their target messenger RNAs (mRNAs), leading to mRNA degradation, suppression of translation or even gene activation. These molecules are promising therapeutic targets and demonstrate great potential as diagnostic biomarkers for disease. This review aims to describe the most recent findings regarding the important roles of miRNAs in diabetes and its complications, with special attention given to the different phases of diabetic wound healing.

  14. Modelling of ICRF heating in DEMO with special emphasis on bulk ion heating

    SciTech Connect

    Gallart, Dani; Mantsinen, Mervi; Kazakov, Yevgen

    2015-12-10

    Ion cyclotron resonance frequency (ICRF) heating is one of the auxiliary heating schemes presently envisaged for ITER and DEMO. In this paper we analyse the potential of ICRF waves to heat the fuel ions in DEMO. Our analysis is carried out for the DEMO1 Reference Scenario from October 2013 (B = 6.8 T, I = 18.6 MA, R = 9.25 m, a = 2.64 m) optimized for a maximum pulse length of 2.3 hrs using the ICRF modelling codes PION and TORIC. We focus on second harmonic heating of tritium and fundamental minority heating of {sup 3}He ions (with a few percent of {sup 3}He) in a 50%:50% D-T plasma. The dependence of the ICRF characteristics and the ICRF-accelerated ions on the ICRF and plasma parameters is investigated, giving special attention to the DEMO design point at a core plasma temperature of 30 keV and an electron density of 1.2·10{sup 20} m{sup −3}.

  15. The Role of MicroRNAs in Diabetic Complications—Special Emphasis on Wound Healing

    PubMed Central

    Moura, João; Børsheim, Elisabet; Carvalho, Eugenia

    2014-01-01

    Overweight and obesity are major problems in today’s society, driving the prevalence of diabetes and its related complications. It is important to understand the molecular mechanisms underlying the chronic complications in diabetes in order to develop better therapeutic approaches for these conditions. Some of the most important complications include macrovascular abnormalities, e.g., heart disease and atherosclerosis, and microvascular abnormalities, e.g., retinopathy, nephropathy and neuropathy, in particular diabetic foot ulceration. The highly conserved endogenous small non-coding RNA molecules, the micro RNAs (miRNAs) have in recent years been found to be involved in a number of biological processes, including the pathogenesis of disease. Their main function is to regulate post-transcriptional gene expression by binding to their target messenger RNAs (mRNAs), leading to mRNA degradation, suppression of translation or even gene activation. These molecules are promising therapeutic targets and demonstrate great potential as diagnostic biomarkers for disease. This review aims to describe the most recent findings regarding the important roles of miRNAs in diabetes and its complications, with special attention given to the different phases of diabetic wound healing. PMID:25268390

  16. Sports-related acute and chronic avulsion injuries in children and adolescents with special emphasis on tennis.

    PubMed

    Vandervliet, Everhard J M; Vanhoenacker, Filip M; Snoeckx, Annemie; Gielen, Jan L; Van Dyck, Pieter; Parizel, Paul M

    2007-11-01

    Acute and chronic sports-related muscle and tendon injuries are not infrequent in youngsters. In particular, the physis is prone to trauma as it constitutes the weakest part of the immature skeleton. The type of sports activity determines the location of the lesion. Most commonly, apophyses of the hip and pelvis are subject to avulsion. The purpose of this paper is to give a short overview of the pathogenesis, location, prevalence and imaging characteristics of acute and chronic avulsion injuries in the immature skeleton, with special emphasis on tennis-related injuries. Tennis-related injuries particularly involve apophyses of the ischial tuberosity, the anterior inferior or superior iliac spine and the iliac crest.

  17. Isolation of compound and CNS depressant activities of Mikania scandens Willd with special emphasis to brain biogenic amines in mice.

    PubMed

    Pal, Dilipkumar; Mazumder, Upal Kanti

    2014-12-01

    Mikania scandens, a twining herb that grows as a weed in India and Bangladesh is used as vegetables and is a good source of vitamin A, C, B complex, mikanin, sesquiterpenes, betasitosterin, stigmasterol and friedelin. The present communication reports CNS depressant activities with special emphasis to brain biogenic amines in mice. Ethanol extract of leaves of M. scandens (EEMS) was prepared by Soxhalation and analyzed chemically. EEMS potentiated sleeping time induced by pentobarbitone, diazepam and meprobamate and showed significant reduction in the number of writhes and stretches. EEMS caused significant protection against pentylene tetrazole-induced convulsion and increased catecholamines and brain amino acids level significantly. Results showed that EEMS produced good CNS depressant effects in mice.

  18. [The federal participation law : New requirements for needs assessment with special emphasis on medical rehabilitation services].

    PubMed

    Schubert, Michael; Schian, Marcus; Viehmeier, Sarah

    2016-09-01

    The federal participation law (Bundesteilhabegesetz - BTHG) is one of the largest efforts in the last 15 years to reform the legal participation rights of people with disabilities. In particular, a number of enhancements are planned in the overall benefits law in Part 1 of Book IX in the Social Code (Sozialgesetzbuch - SGB), which applies to all rehabilitation carriers including general provisions and standards for needs assessment. This paper deals with the implications of these provisions and interacting standards, based on the draft bill of April 2016.The discussion takes place against the background of the regulatory objectives formulated in the ministerial draft itself, jurisprudential expertise on the effects of the current legal norms of the SGB IX as well as relevant professional political developments and statements by various stakeholders.The analysis shows a clear political commitment to increase the requirements for needs assessment in the overall law of the SGB IX and to express these more effectively. The draft bill seeks not only to modify procedures subsequent to the application for rehabilitation benefits, but also to precisely set out provisions on instruments for needs assessment in a new § 13. Common principles for these instruments of needs assessment should increase the cooperation, coordination and convergence among rehabilitation carriers.Nevertheless, with regard to the proposed regulatory texts, there is doubt that the objectives set by the draft bill itself will be achieved. For example, the required common principles for needs assessment are to be agreed upon based on the existing special legislation for the different rehabilitation carriers, without the SGB IX setting its own binding standards or framework principles. In addition, it lacks clear legal guidelines for the professional practice to make use of the bio-psycho-social model of the WHO and the ICF in the process of needs assessment. As a consequence the ICF cannot

  19. Interventions to Reduce Drug Abuse in Pars Special Economic Energy Zone

    PubMed Central

    Damari, Behzad; Ahmadi Pishkuhi, Mahin; Masoudiasl, Irvan; Bostanmanesh, Golamreza

    2015-01-01

    Background: South Pars special economic energy zone is the world's second largest gas reservoir that was established two decades ago. High incidence of social harms is observed in this region due to various problems such as drug addiction which is of high prevalence. Objectives: The current study aimed at finding the strategies to prevent drug abuse and formulating policies in the region. Materials and Methods: The research method was a combination of nested type (qualitative-quantitative) and analysis of participated stakeholders’ views. The study was conducted from January 2014 to May 2015 in Bushehr province. Intentional sampling was used in qualitative section. Collected data were classified in 3 areas: recognition, directions, and implementation requirements. Results: Different factors were identified affecting the prevalence of drug addiction. Various prevention and treatment interventions have been conducted in response to drug abuse in the region, though they have been often sectional, insular, inconsistent, and immeasurable in terms of impact. After the study, a combination of compulsory, facilitative, and promotional interventions was proposed to reduce drug abuse by 10% within a strategic 5-year plan. These interventions are based on 3 aspects: people, industry, and governance, which have been announced and approved based on a memorandum of understanding. Conclusions: It is necessary to implement simultaneous national interventions as soon as possible to improve the economic, social, political, technological, international, and environmental conditions. In the current study, unlike the previous attempts, national stakeholders, including ministry of petroleum, ministry of health and medical education, interior ministry, ministry of cooperatives, labor, and social welfare, and Iran drug control headquarters have played active roles. This fact is evident in their formulation of a policy document in the region and action plan after reaching a memorandum of

  20. 78 FR 25755 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-02

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis Panel; RFA AA13-001, Specialized Alcohol Research Centers. Date: August 15, 2013. Time: 1:00 p.m. to...

  1. 77 FR 39716 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-05

    ... Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting Pursuant to section 10(d) of the Federal... and Alcoholism Special Emphasis Panel, Review of RFA AA-12-009. Date: July 17-19, 2012. Time: 10:00...

  2. 75 FR 63498 - National Institute on Drug Abuse; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... Pursuant to section 10(d) of the Federal Advisory Committee Act, as amended (5 U.S.C. App), notice is... Committee: National Institute on Drug Abuse Special Emphasis Panel; Statistical Analysis in Support of...

  3. Current drug therapy of patients with BPH-LUTS with the special emphasis on PDE5 inhibitors

    PubMed Central

    Govorov, Alexander; Kasyan, George; Priymak, Diana; Pushkar, Dmitry

    2016-01-01

    Introduction Benign prostatic hyperplasia (BPH) is the most common cause of lower urinary tract symptom (LUTS) development in men [1]. The intensity of the symptoms may vary from mild to severe, significantly affecting the quality of life. Erectile dysfunction (ED) is one of the most challenging issues in modern urology that significantly influences the quality of life in men worldwide. The objective of this literature review was to analyze the current drug therapies of patients with BPH-LUTS, with the special emphasis on PDE5 inhibitors. Material and methods The authors searched the literature for the period from 2000 until 2015 in MEDLINE and PubMed. Results Twenty-three articles were selected based on their reliability. A detailed analysis of the selected papers was performed. Primary attention was given to articles describing the use of PDE5. Works describing the use of different groups of drugs in patients with BPH-LUTS were also selected. Conclusions The current literature analysis suggests that the introduction of PDE5 inhibitors in clinical practice for the treatment of patients with BPH-LUTS will allow for significant expansion of the therapeutic options for the treatment of this disease. PMID:28127458

  4. Evolution, molecular epidemiology and perspectives on the research of taeniid parasites with special emphasis on Taenia solium.

    PubMed

    Bobes, Raúl J; Fragoso, Gladis; Fleury, Agnès; García-Varela, Martín; Sciutto, Edda; Larralde, Carlos; Laclette, Juan P

    2014-04-01

    Human cysticercosis is known since old historical times in Greece and China; however, human infections by tapeworms have accompanied human beings for more that hundred thousand years. The disease is tightly bound to poverty and lack of hygiene, and has been eradicated in developed countries, but continues being a public health problem in developing countries of Latin-American, Sub-Saharan Africa and Asia, and is also remerging in a number of non endemic countries. It is considered a neglected disease. Here we revise a number of key scientific contributions on taeniid biology that open new avenues for more effective approaches to the control of cysticercosis. The evolution of flatworms and class Cestoda is analyzed, with special emphasis on the emergence of taeniid parasites and the colonization of the human species by tapeworms. The complex molecular host-parasite interplay in this relationship as result of co-evolution between two distantly related organisms. The relevant host and parasite's factors, in the prospect of identifying species-specific molecular markers useful in epidemiological studies carried out in endemic countries. The new possibilities arising with the characterization of the genomes for several species of tapeworms, including a deeper understanding of these organisms, as well as improved tools for diagnosis, vaccination and drug treatment. The need to revise the current control and management strategies for this tropical neglected disease.

  5. Biogeography in Cellana (Patellogastropoda, Nacellidae) with Special Emphasis on the Relationships of Southern Hemisphere Oceanic Island Species.

    PubMed

    González-Wevar, Claudio A; Nakano, Tomoyuki; Palma, Alvaro; Poulin, Elie

    2017-01-01

    Oceanic islands lacking connections to other land are extremely isolated from sources of potential colonists and have acquired their biota mainly through dispersal from geographically distant areas. Hence, isolated island biota constitutes interesting models to infer biogeographical mechanisms of dispersal, colonization, differentiation, and speciation. Limpets of the genus Cellana (Nacellidae: Patellogastropoda) show limited dispersal capacity but are broadly distributed across the Indo-Pacific including many endemic species in isolated oceanic islands. Here, we examined main distributional patterns and geographic boundaries among Cellana lineages with special emphasis in the relationships of Southern Hemisphere oceanic islands species. Phylogenetic reconstructions based on mtDNA (COI) recognized three main clades in Cellana including taxa from different provinces of the Indo-Pacific. Clear genetic discontinuities characterize the biogeography of Cellana and several lineages are associated to particular areas of the Indo-Pacific supporting the low dispersal capacity of the genus across recognized biogeographical barriers in the region. However, evolutionary relationships within Cellana suggest that long-distance dispersal processes have been common in the history of the genus and probably associated to the origin of the species in Hawaii and Juan Fernández Archipelago. Therefore, the presence of Cellana species in geographically distant Southern Hemisphere oceanic islands, such as the Juan Fernández Archipelago, suggests that long-distance dispersal mediated by rafting may have played an important role in the biogeography of the genus.

  6. Reformulated and alternative fuels: modeled impacts on regional air quality with special emphasis on surface ozone concentration.

    PubMed

    Schell, Benedikt; Ackermann, Ingmar J; Hass, Heinz

    2002-07-15

    The comprehensive European Air Pollution and Dispersion model system was used to estimate the impacts of the usage of reformulated and alternative fuels on regional air quality with special emphasis on surface ozone concentrations. A severe western European summer smog episode in July 1994 has been used as a reference, and the model predictions have been evaluated for this episode. A forecast simulation for the year 2005 (TREND) has been performed, including the future emission development based on the current legislation and technologies available. The results of the scenario TREND are used as a baseline for the other 2005 fuel scenarios, including fuel reformulation, fuel sulfur content, and compressed natural gas (CNG) as an alternative fuel. Compared to the year 1994, significant reductions in episode peak ozone concentrations and ozone grid hours are predicted for the TREND scenario. These reductions are even more pronounced within the investigated alternative and reformulated fuel scenarios. Especially, low sulfur fuels are appropriate for an immediate improvement in air quality, because they effect the emissions of the whole fleet. Furthermore, the simulation results indicate that the introduction of CNG vehicles would also enhance air quality with respect to ozone.

  7. Overview of the physiology and pathophysiology of leptin with special emphasis on its role in the kidney.

    PubMed

    Nasrallah, Mona P; Ziyadeh, Fuad N

    2013-01-01

    The adipocyte product leptin is a pleiotropic adipokine and hormone, with a role extending beyond appetite suppression and increased energy expenditure. This review summarizes the biology of the leptin system and the roles of its different receptors in a multitude of cellular functions in different organs, with special emphasis on the kidney. Leptin's physiological functions as well as deleterious effects in states of leptin deficiency or hyperleptinemia are emphasized. Chronic hyperleptinemia can increase blood pressure through the sympathetic nervous system and renal salt retention. The concept of selective leptin resistance in obesity is emerging, whereby leptin's effect on appetite and energy expenditure is blunted, with a concomitant increase in leptin's other effects as a result of the accompanying hyperleptinemia. The divergence in response likely is explained by different receptors and post-receptor activating mechanisms. Chronic kidney disease is a known cause of hyperleptinemia. There is an emerging view that the effect of hyperleptinemia on the kidney can contribute to the development and/or progression of chronic kidney disease in selective resistance states such as in obesity or type 2 diabetes mellitus. The mechanisms of renal injury are likely the result of exaggerated and undesirable hemodynamic influences as well as profibrotic effects.

  8. Biogeography in Cellana (Patellogastropoda, Nacellidae) with Special Emphasis on the Relationships of Southern Hemisphere Oceanic Island Species

    PubMed Central

    Nakano, Tomoyuki; Palma, Alvaro; Poulin, Elie

    2017-01-01

    Oceanic islands lacking connections to other land are extremely isolated from sources of potential colonists and have acquired their biota mainly through dispersal from geographically distant areas. Hence, isolated island biota constitutes interesting models to infer biogeographical mechanisms of dispersal, colonization, differentiation, and speciation. Limpets of the genus Cellana (Nacellidae: Patellogastropoda) show limited dispersal capacity but are broadly distributed across the Indo-Pacific including many endemic species in isolated oceanic islands. Here, we examined main distributional patterns and geographic boundaries among Cellana lineages with special emphasis in the relationships of Southern Hemisphere oceanic islands species. Phylogenetic reconstructions based on mtDNA (COI) recognized three main clades in Cellana including taxa from different provinces of the Indo-Pacific. Clear genetic discontinuities characterize the biogeography of Cellana and several lineages are associated to particular areas of the Indo-Pacific supporting the low dispersal capacity of the genus across recognized biogeographical barriers in the region. However, evolutionary relationships within Cellana suggest that long-distance dispersal processes have been common in the history of the genus and probably associated to the origin of the species in Hawaii and Juan Fernández Archipelago. Therefore, the presence of Cellana species in geographically distant Southern Hemisphere oceanic islands, such as the Juan Fernández Archipelago, suggests that long-distance dispersal mediated by rafting may have played an important role in the biogeography of the genus. PMID:28099466

  9. Selenol protecting groups in organic chemistry: special emphasis on selenocysteine Se-protection in solid phase peptide synthesis.

    PubMed

    Flemer, Stevenson

    2011-04-18

    The appearance of selenium in organic synthesis is relatively rare, and thus examples in the literature pertaining to the masking of its considerable reactivity are similarly uncommon. Greene's Protecting Groups in Organic Synthesis, the standard reference for the state of the art in this arena, offers no entries for selenium protective methodology, in stark comparison to its mention of the great variety of protecting groups germane to its chalcogen cousin sulfur. This scarcity of Se-protection methods makes it no less interesting and pertinent toward the construction of selenium-containing organic systems which do indeed require the iterative blocking and de-blocking of selenol functionalities. A selenium-containing system which is especially relevant is selenocysteine, as its use in Solid Phase Peptide Synthesis requires extensive protection of its selenol side chain. This review will attempt to summarize the current state of understanding with regard to selenium protection protocol in organic synthesis. Moreover, it will provide a special emphasis on selenocysteine side chain protection, comprising both the breadth of functionality used for this purpose as well as methods of deprotection.

  10. Genetic and perinatal effects of abused substances

    SciTech Connect

    Brande, M.C.; Zimmerman, A.M.

    1987-01-01

    This book provides an overview of the effects of several abused drugs, including opiates, cannabinoids, alcohol, nicotine, and cocaine, with special emphasis on the actions of these substances at the molecular and cellular levels. The first half deals with genetic effects, including molecular genetics, biochemical genetics, pharmacogenetics, cytogenetics, and genetic toxicity. The second half focuses on perinatal effects and covers: drug abuse during pregnancy; biochemical aspects of marihuana on male reproduction; and long-term behavioral and neuroendocrine effects of perinatal alcohol exposure.

  11. Integrated plant nutrient system - with special emphasis on mineral nutriton and biofertilizers for Black pepper and cardamom - A review.

    PubMed

    K P, Sangeeth; R, Suseela Bhai

    2016-05-01

    Integrated Plant Nutrition System (IPNS) as a concept and farm management strategy embraces and transcends from single season crop fertilization efforts to planning and management of plant nutrients in crop rotations and farming systems on a long-term basis for enhanced productivity, profitability and sustainability. It is estimated that about two-thirds of the required increase in crop production in developing countries will have to come from yield increases from lands already under cultivation. IPNS enhances soil productivity through a balanced use of soil nutrients, chemical fertilizers, combined with organic sources of plant nutrients, including bio-inoculants and nutrient transfer through agro-forestry systems and has adaptation to farming systems in both irrigated and rainfed agriculture. Horticultural crops, mainly plantation crops, management practices include application of fertilizers and pesticides which become inevitable due to the depletion of soil organic matter and incidence of pests and diseases. The extensive use of chemical fertilizers in these crops deteriorated soil health that in turn affected the productivity. To revitalize soil health and to enhance productivity, it is inexorable to enrich the soil using microorganisms. The lacunae observed here is the lack of exploitation of indigenous microbes having the potential to fix atmospheric nitrogen (N) and to solubilize Phosphorus (P) and Potassium (K). The concept of biofertilizer application appears to be technically simple and financially feasible, but the task of developing biofertilizers with efficient strains in appropriate combinations in a consortia mode is not easier. More than developing consortia, a suitable delivery system to discharge the microbial inoculants warranted much effort. This review focuses on the integrated plant nutrition system incorporating biofertilizer with special emphasis on developing and formulating biofertilizer consortium.

  12. [Lipidic pattern of 25 Mexican marine fishes with special emphasis in their n-3 fatty acids as nutraceuticals components].

    PubMed

    Castro-González, María Isabel; Ojeda, Anayté; Silencio, José Luis; Cassis, Lorena; Ledesma, Hector; Pérez-Gil, Fernando

    2004-09-01

    The aim of this study was to characterize and to evaluate the lipidic composition of mexican marine fishes with special emphasis in n-3 fatty acids as nutraceuticals. The edible portion of 25 species: humidity (H), crude protein (CP), total lipids (TL) and fatty acids (FA). The average content (g/100g edible portion) of H was 75.20, PC was 18.40, TL was 3.60. Four n-3 FA were identified in all the samples and they were found in the next abundance order (mg/100g edible portion): C22:6n-3 (DHA)(229.60), C20:5 n-3 (EPA)(52.10), C18:3 n-3 (ALA)(11.80) and C20:3 n-3 (2.25). By their origin and climate there were no difference. By their biologycal classification, n-3 FA content was higher in bony fishes than cartilaginous fishes. It was detected a proportional relation with the n-3 FA concentration and total lipid content. According to their ecotic distribution there were numerical differences in DHA content (mg/100g edible portion) between pelagics (420.70), benthopelagics (125.30) and demersals fishes (225.40). Fatty fishes had higher content of EPA and DHA (mg/100g edible portion) (109.27 and 552.72) than semifatty fishes (56.12 and 226.29) and leanness (15.95 and 96.52), respectively. Bony, fatty and pelagic fishes had a higher content of EPA+DHA. According with the international recommendation values (200 to 600 mg EPA+DHA/day) the 44% of the analyzed species could be considered as functional foods due to their high content of EPA + DHA in a range of 220 to 1300 mg/100g.

  13. NEURODEVELOPMENTAL BIOLOGY ASSOCIATED WITH CHILDHOOD SEXUAL ABUSE

    PubMed Central

    De Bellis, Michael D.; Spratt, Eve G.; Hooper, Stephen R.

    2013-01-01

    Child maltreatment appears to be the single most preventable cause of mental illness and behavioral dysfunction in the US. There are few published studies examining the developmental and the psychobiological consequences of sexual abuse. There are multiple mechanisms through which sexual abuse can cause PTSD, activate biological stress response systems, and contribute to adverse brain development. This article will critically review the psychiatric problems associated with maltreatment and the emerging biologic stress system research with a special emphasis on what is known about victimization by sexual abuse. PMID:21970646

  14. 78 FR 75927 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-13

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis... Alcoholism, 5635 Fishers Lane, (Teleconference), Rockville, MD 20852. Contact Person: Richard A. Rippe,...

  15. 75 FR 62553 - National Institute on Alcohol Abuse and Alcoholism; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Amended... Abuse and Alcoholism Special Emphasis Panel, November 3, 2010, 2 p.m. to November 3, 2010, 5...

  16. 77 FR 14023 - National Institute on Alcohol Abuse and Alcoholism; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Amended... Abuse and Alcoholism Special Emphasis Panel, March 28, 2012, 4 p.m. to March 29, 2012, 8 p.m.,...

  17. 76 FR 44600 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-26

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis Panel, RFA AA-12-001 DNA Repository for the NIAAA NESARC--III (U24). Date: August 5, 2011. Time: 11...

  18. 77 FR 72873 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-12-06

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis Panel; NIAAA Member Conflict Applications--Basic Sciences. Date: December 19, 2012. Time: 1:00 p.m. to...

  19. 76 FR 44597 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-26

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis Panel; NIAAA--Member Conflict applications--K Series. Date: August 2, 2011. Time: 2 to 3:30 p.m....

  20. 75 FR 8726 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-02-25

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis Panel, Review of Applications on Case Ascertainment to Estimate the U.S. Prevalence of Fetal...

  1. 76 FR 44596 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-26

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis Panel, Institutional Training Grant Review. Date: October 11, 2011. Time: 8 a.m. to 8 p.m. Agenda:...

  2. 77 FR 64117 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-18

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... of personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis Panel. Name of Committee: Date: November 5, 2012. Time: 2:30 p.m. to 5:30 p.m. Agenda: To...

  3. 75 FR 63494 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-15

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis Panel; NIAAA Member Conflict Applications--Biosciences. Date: October 28, 2010. Time: 11 a.m. to 2...

  4. 75 FR 24961 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-06

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis Panel; NADIA Consortium Review (IN). Date: May 19, 2010. Time: 8 a.m. to 7 p.m. Agenda: To review...

  5. 76 FR 31967 - National Institute on Drug Abuse; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-02

    ... the review and funding cycle. (Catalogue of Federal Domestic Assistance Program Nos.: 93.279, Drug... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meeting... Committee: National Institute on Drug Abuse Special Emphasis Panel; N01DA-11-7777: Synthesis...

  6. 78 FR 17680 - National Institute on Alcohol Abuse and Alcoholism; Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-22

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Closed... of Committee: National Institute on Alcohol Abuse and Alcoholism, Special Emphasis Panel, NIAAA... . (Catalogue of Federal Domestic Assistance Program Nos. 93.273, Alcohol Research Programs; National...

  7. 78 FR 37836 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-24

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis... No. 93.273, Alcohol Research Programs; National Institutes of Health, HHS) ] Dated: June 18,...

  8. 78 FR 12072 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-21

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis... . (Catalogue of Federal Domestic Assistance Program Nos. 93.273, Alcohol Research Programs; National...

  9. 78 FR 13361 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-27

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  10. 78 FR 37836 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

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    2013-06-24

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  11. 78 FR 63484 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-24

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis... 2013. (Catalogue of Federal Domestic Assistance Program No. 93.273, Alcohol Research Programs;...

  12. 78 FR 37835 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-24

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis... No. 93.273, Alcohol Research Programs; National Institutes of Health, HHS) Dated: June 18,...

  13. 78 FR 37837 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-24

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis....273, Alcohol Research Programs; National Institutes of Health, HHS) Dated: June 18, 2013. Carolyn...

  14. 76 FR 59708 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-27

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special Emphasis..., Alcohol Research ] Career Development Awards for Scientists and Clinicians; 93.272, Alcohol...

  15. 78 FR 57166 - National Institute on Drug Abuse; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-09-17

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meetings... of Committee: National Institute on Drug Abuse Special Emphasis Panel; Ruth L. Kirschstein National...-Wesley, Ph.D., Scientific Review Officer, Office of Extramural Affairs, National Institute on Drug...

  16. 75 FR 3239 - National Institute on Drug Abuse; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-01-20

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meetings... Committee: National Institute on Drug Abuse; Special Emphasis Panel; Clinical Trials Network. Date: February..., PhD, Scientific Review Administrator, Office of Extramural Affairs, National Institute on Drug...

  17. 75 FR 9606 - National Institute on Drug Abuse; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-03

    ... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed Meetings... Committee: National Institute on Drug Abuse Special Emphasis Panel NIDA-K Conflicts. Date: March 8, 2010..., PhD, Scientific Review Administrator, Office of Extramural Affairs, National Institute on Drug...

  18. Guide to National Data on Maternal and Child Health with Special Emphasis on Financing Services for Chronically Ill Children.

    ERIC Educational Resources Information Center

    McManus, Margaret A.; And Others

    The major purposes of this guide are to: (1) identify available national data on maternal and child health, with emphasis on costs of care and insurance coverage for chronically ill children; (2) explain to the reader how to use such data; and (3) offer recommendations for improving future collection and analysis of national data. The guide is…

  19. A Quantitative Analysis of Special Needs with Emphasis on Speech and Hearing in the Boston Public Schools.

    ERIC Educational Resources Information Center

    Wilson, Mazzie R.; Stewart, James Monroe

    1983-01-01

    The primary prototypes and educational goals used to educate Boston, Massachusetts, public school children with special needs (mainstreamed children) were analyzed and a demographic profile was developed. The results indicated that the special needs of the school children were not in close proportion to their racial distribution. (Author/SEW)

  20. Preparing Research Leaders for Special Education: A Ph.D. Program with an Emphasis in Applied Behavior Analysis.

    ERIC Educational Resources Information Center

    Heward, William L.; And Others

    1995-01-01

    An Ohio State University doctoral program for special education leadership personnel emphasizing applied behavior analysis is described. The program features intensive formal coursework, special topic seminars, participation in three research studies prior to dissertation, supervised college teaching and advising experiences, and a 10-week summer…

  1. Current concepts in the recognition and classification of pain with special emphasis on orofacial pain: a review.

    PubMed

    Muriithi, A W; Chindia, M L

    1993-11-01

    Despite extensive investigation, pain cannot always be adequately diagnosed or cured. Subsequently, the management of pain can be daunting. The diagnosis of pain, however, is crucial to its effective management because of the grave influence that pain has on the quality of life. The biggest drawback in the management of pain is the lack of understanding, on the part of the practitioner, of the peripheral and central modulation of pain. The objective of this paper is to briefly review the current concepts in the recognition of and classification of pain, with emphasis on orofacial pain.

  2. An Ego-Strengthening Approach with Multiply Traumatized Children: Special Reference to the Sexually Abused

    ERIC Educational Resources Information Center

    Crenshaw, David A.; Mordock, John B.

    2004-01-01

    Seven basic tasks are presented that must be accomplished for successful residential treatment of multiply abused children, and methods are described to achieve each task. The tasks are: empowering the children, respecting their need for privacy, helping them to feel safe and creating "safety nets" for them, building and supporting their defenses,…

  3. Orientation to Trades and Technology. A Curriculum Guide and Resource Book with Special Emphasis on the Needs of Women. Revised.

    ERIC Educational Resources Information Center

    Braundy, Marcia

    This combination curriculum guide and resource book was developed in response to recommendations made by the instructors who attended the Women in Trades and Technology (WITT) conference of June 1986. It assists in the design and delivery of exploratory trade and technology courses that are responsive to the special needs of women learners…

  4. Phosphorus homeostasis in normal health and in chronic kidney disease patients with special emphasis on dietary phosphorus intake.

    PubMed

    Uribarri, Jaime

    2007-01-01

    Elevated serum phosphorus has been identified as a cardiovascular risk factor in chronic kidney disease (CKD) patients and a clear understanding of phosphorus homeostasis is very important for practicing nephrologists. At any particular point, serum phosphorus levels reflect the balance between movements of this mineral from and into the intestine, bone, intracellular space, and kidneys. We briefly review here all these exchanges with a particular emphasis on dietary phosphorus intake. Despite all the oral phosphorus binders currently available in the market, dietary restriction of this mineral remains a cornerstone for the prevention and treatment of hyperphosphatemia. An effective restriction of dietary intake of phosphorus requires prescription of a moderate protein intake (0.9-1.0 g/kg/day) and restricted consumption of highly processed fast and convenience foods. Phosphorus added during food processing is an important source of this mineral because of its magnitude and high bioavailabilty. Moreover, as food manufacturers are not required to label the amount of phosphorus added during food processing, a significant amount of the current daily phosphorus intake remains unaccounted when estimating phosphorus intake in CKD patients. The recent development of low phosphorus-containing food products represents a very useful addition for CKD patients.

  5. Phytoplankton dynamics with a special emphasis on harmful algal blooms in the Mar Piccolo of Taranto (Ionian Sea, Italy).

    PubMed

    Caroppo, Carmela; Cerino, Federica; Auriemma, Rocco; Cibic, Tamara

    2016-07-01

    The response of phytoplankton assemblages to the closure of urban sewage outfalls (USOs) was examined for the Mar Piccolo of Taranto (Mediterranean Sea), a productive semi-enclosed coastal marine ecosystem devoted to shellfish farming. Phytoplankton dynamics were investigated in relation to environmental variables, with a particular emphasis on harmful algal blooms (HABs). Recent analyses evidenced a general reduction of the inorganic nutrient loads, except for nitrates and silicates. Also phytoplankton biomass (chlorophyll a) and abundances were characterized by a decrease of the values, except for the inner area of the basin (second inlet). The phytoplankton composition changed, with nano-sized species, indicators of oligotrophic conditions, becoming dominant over micro-sized species. If the closure of the USOs affected phytoplankton dynamics, however, it did not preserve the Mar Piccolo from HABs and anoxia crises. About 25 harmful species have been detected throughout the years, such as the potentially domoic acid producers Pseudo-nitzschia cf. galaxiae and P seudo-nitzschia cf. multistriata, identified for the first time in these waters. The presence of HABs represents a threat for human health and aquaculture. Urgent initiatives are needed to improve the communication with authorities responsible for environmental protection, economic development, and public health for a sustainable mussel culture in the Mar Piccolo.

  6. Seasonal dynamics of zooplankton in Columbia–Snake River reservoirs,with special emphasis on the invasive copepod Pseudodiaptomus forbesi

    USGS Publications Warehouse

    Emerson, Joshua E.; Bollens, Stephen M.; Counihan, Timothy D.

    2015-01-01

    The Asian copepod Pseudodiaptomus forbesi has recently become established in the Columbia River. However, little is known about its ecology and effects on invaded ecosystems. We undertook a 2-year (July 2009 to June 2011) field study of the mesozooplankton in four reservoirs in the Columbia and Snake Rivers, with emphasis on the relation of the seasonal variation in distribution and abundance of P. forbesi to environmental variables. Pseudodiaptomus forbesi was abundant in three reservoirs; the zooplankton community of the fourth reservoir contained no known non-indigenous taxa. The composition and seasonal succession of zooplankton were similar in the three invaded reservoirs: a bloom of rotifers occurred in spring, native cyclopoid and cladoceran species peaked in abundance in summer, and P. forbesi was most abundant in late summer and autumn. In the uninvaded reservoir, total zooplankton abundance was very low year-round. Multivariate ordination indicated that temperature and dissolved oxygen were strongly associated with zooplankton community structure, with P. forbesi appearing to exhibit a single generation per year . The broad distribution and high abundance of P. forbesi in the Columbia–Snake River System could result in ecosystem level effects in areas intensively managed to improve conditions for salmon and other commercially and culturally important fish species. 

  7. A process-based model of conifer forest structure and function with special emphasis on leaf lifespan

    NASA Astrophysics Data System (ADS)

    Osborne, Colin P.; Beerling, David J.

    2002-12-01

    We describe the University of Sheffield Conifer Model (USCM), a process-based approach for simulating conifer forest carbon, nitrogen, and water fluxes by up-scaling widely applicable relationships between leaf lifespan and function. The USCM is designed to predict and analyze the biogeochemistry and biophysics of conifer forests that dominated the ice-free high-latitude regions under the high pCO2 "greenhouse" world 290-50 Myr ago. It will be of use in future research investigating controls on the contrasting distribution of ancient evergreen and deciduous forests between hemispheres, and their differential feedbacks on polar climate through the exchange of energy and materials with the atmosphere. Emphasis is placed on leaf lifespan because this trait can be determined from the anatomical characteristics of fossil conifer woods and influences a range of ecosystem processes. Extensive testing of simulated net primary production and partitioning, leaf area index, evapotranspiration, nitrogen uptake, and land surface energy partitioning showed close agreement with observations from sites across a wide climatic gradient. This indicates the generic utility of our model, and adequate representation of the key processes involved in forest function using only information on leaf lifespan, climate, and soils.

  8. Buoyancy-generating agents for stomach-specific drug delivery: an overview with special emphasis on floating behavior.

    PubMed

    Ishak, Rania A H

    2015-01-01

    Gastric retentive drug delivery provides a promising technology exhibiting an extended gastric residence and a drug release independent of patient related variables. It is usually useful in improving local gastric treatment as well as overcoming drug-related problems .i.e. drugs having narrow absorption window, short half-life or low intestinal solubility. Buoyancy is considered one of the most promising approaches for gastro-retention of dosage forms. Floating drug delivery systems have a bulk density lower than gastric fluids and thus remain buoyant in the stomach causing an increase in gastric residence time. The buoyancy of these systems is attained by the aid of substances responsible to generate the low density. Various agents with different mechanisms were adopted either gas-generating agents, air entrapping swellable polymers, inherent low density substances, porous excipients, hollow/porous particles inducing preparation techniques or sublimating agents. Therefore, this review gives an exclusive descriptive classification of the different categories of these buoyancy-generating agents while representing the related research works. An overview is also conducted to describe relevant techniques assessing the floating behavior of such dosage forms either in vitro or in vivo. Finally, a collection representing FDA-approved floating pharmaceutical products is adopted with emphasis on the buoyancy-generating agent type used in each product.

  9. [Physical and gynecological examinations in female victims of sexual violence with special emphasis on crime-reporting behaviour].

    PubMed

    Germerott, Tanja; Bode-Jänisch, Stefanie; Thali, Michael J

    2012-01-01

    Sexual abuse of females is a common form of violence with a high dark figure. While part of the victims decide to report the event to the police, many women are embarrassed to do so for a number of reasons. Retrospectively, examinations performed in Berne (Switzerland) between 2006 and 2008 in cases with and without report to the police were analyzed. Altogether, 207 examinations were carried out during that period (65.2% reported to the police, 34.8% without report to the police). 20% of the incidents were reported to the police after the examination. One third of the victims in both groups claimed that the perpetrator was unknown to them. More than 40% of the women in both groups had been under the influence of alcohol at the time of the incident. 73% of the victims (reporting the crime) and 61% of those not filing a crime report described penile-vaginal contacts. Blackouts were claimed in 14% of the cases reported to the police and 33% of those not reported. Genital lesions were found in about one third and extragenital injuries in more than 50% of cases in both groups. No condom had been used in a large percentage of cases or its use was uncertain. Unprotected vaginal ejaculation was reported by about one third of the victims in both groups and could not be reliably excluded in 28% of cases. In 43.8% (reported to police) and 47.1% (not reported), no contraceptive method had been applied by the women. The results of the present study show similar distributions in both groups for numerous factors (factual circumstances and injury pattern). However, in the group not filing a complaint with the police blackouts were reported more often, which may have induced the victims not to report the incident to the police at first. The fact that in about 20% of these cases the women went to the police later underlines the importance of offering documentation usable as evidence in court and preserving evidence independent of whether the incident has already been reported to

  10. DRUG ABUSE IN INDIA: AN OVERVIEW WITH SPECIAL REFERENCE TO CANNABIS

    PubMed Central

    Sethi, B.B.; Tiwari, S.C.; Kumar, Pradeep; Trivedi, J.K.

    1984-01-01

    SUMMARY The Indian literature related to drug abuse in general and Cannabis in particular has been reviewed and possible implications discussed. In this regard to solve the existing controversy, 50 pure chronic cannabis users were evaluated for their physical, mental, cognitive and socio economic functions and the results were compared with a matched control group. Results of this study did not reveal any impairment in these areas It is concluded that cannabis, in India, may not be as much injurious to health as has often been mentioned in Western Countries. Future areas of research have been suggested. PMID:21965957

  11. Effects of ionizing radiation on the immune system with special emphasis on the interaction of dendritic and T cells.

    PubMed

    Manda, Katrin; Glasow, Annegret; Paape, Daniel; Hildebrandt, Guido

    2012-01-01

    Dendritic cells (DCs), as professional antigen-presenting cells, are members of the innate immune system and function as key players during the induction phase of adaptive immune responses. Uptake, processing, and presentation of antigens direct the outcome toward either tolerance or immunity. The cells of the immune system are among the most highly radiosensitive cells in the body. For high doses of ionizing radiation (HD-IR) both immune-suppressive effects after whole body irradiation and possible immune activation during tumor therapy were observed. On the other hand, the effects of low doses of ionizing radiation (LD-IR) on the immune system are controversial and seem to show high variability among different individuals and species. There are reports revealing that protracted LD-IR can result in radioresistance. But immune-suppressive effects of chronic LD-IR are also reported, including the killing or sensitizing of certain cell types. This article shall review the current knowledge of radiation-induced effects on the immune system, paying special attention to the interaction of DCs and T cells.

  12. Multidisciplinary Teams in Child Abuse and Neglect Programs. A Special Report from the National Center on Child Abuse and Neglect, August, 1978.

    ERIC Educational Resources Information Center

    Herner and Co., Washington, DC.

    The monograph examines the rationale and scope of multidisciplinary teams in child abuse and neglect cases; and reviews operation of hospital-based, interagency, and state-mandated multidisciplinary team programs. The bulk of the document is composed of two appendixes: a directory of child abuse and neglect programs which use a multidisciplinary…

  13. Long-Term Potentiation at CA3–CA1 Hippocampal Synapses with Special Emphasis on Aging, Disease, and Stress

    PubMed Central

    Kumar, Ashok

    2011-01-01

    Synaptic plasticity in the mammalian central nervous system has been the subject of intense investigation for the past four decades. Long-term potentiation (LTP), a major reflection of synaptic plasticity, is an activity-driven long-lasting increase in the efficacy of excitatory synaptic transmission following the delivery of a brief, high-frequency train of electrical stimulation. LTP is regarded as a principal candidate for the cellular mechanisms involved in learning and offers an attractive hypothesis of how memories are constructed. There are a number of exceptional full-length reviews published on LTP; the current review intends to present an overview of the research findings regarding hippocampal LTP with special emphasis on aging, diseases, and psychological insults. PMID:21647396

  14. Inference, simulation, modeling, and analysis of complex networks, with special emphasis on complex networks in systems biology

    NASA Astrophysics Data System (ADS)

    Christensen, Claire Petra

    's own publications have contributed network inference, simulation, modeling, and analysis methods to the much larger body of work in systems biology, and indeed, in network science. The aim of this thesis is therefore twofold: to present this original work in the historical context of network science, but also to provide sufficient review and reference regarding complex systems (with an emphasis on complex networks in systems biology) and tools and techniques for their inference, simulation, analysis, and modeling, such that the reader will be comfortable in seeking out further information on the subject. The review-like Chapters 1, 2, and 4 are intended to convey the co-evolution of network science and the slow but noticeable breakdown of boundaries between disciplines in academia as research and comparison of diverse systems has brought to light the shared properties of these systems. It is the author's hope that theses chapters impart some sense of the remarkable and rapid progress in complex systems research that has led to this unprecedented academic synergy. Chapters 3 and 5 detail the author's original work in the context of complex systems research. Chapter 3 presents the methods and results of a two-stage modeling process that generates candidate gene-regulatory networks of the bacterium B.subtilis from experimentally obtained, yet mathematically underdetermined microchip array data. These networks are then analyzed from a graph theoretical perspective, and their biological viability is critiqued by comparing the networks' graph theoretical properties to those of other biological systems. The results of topological perturbation analyses revealing commonalities in behavior at multiple levels of complexity are also presented, and are shown to be an invaluable means by which to ascertain the level of complexity to which the network inference process is robust to noise. Chapter 5 outlines a learning algorithm for the development of a realistic, evolving social

  15. Heavy metal concentrations in soils as determined by laser-induced breakdown spectroscopy (LIBS), with special emphasis on chromium.

    PubMed

    Senesi, G S; Dell'Aglio, M; Gaudiuso, R; De Giacomo, A; Zaccone, C; De Pascale, O; Miano, T M; Capitelli, M

    2009-05-01

    Soil is unanimously considered as one of the most important sink of heavy metals released by human activities. Heavy metal analysis of natural and polluted soils is generally conducted by the use of atomic absorption spectroscopy (AAS) or inductively coupled plasma optical emission spectroscopy (ICP-OES) on adequately obtained soil extracts. Although in recent years the emergent technique of laser-induced breakdown spectroscopy (LIBS) has been applied widely and with increasing success for the qualitative and quantitative analyses of a number of heavy metals in soil matrices with relevant simplification of the conventional methodologies, the technique still requires further confirmation before it can be applied fully successfully in soil analyses. The main objective of this work was to demonstrate that new developments in LIBS technique are able to provide reliable qualitative and quantitative analytical evaluation of several heavy metals in soils, with special focus on the element chromium (Cr), and with reference to the concentrations measured by conventional ICP spectroscopy. The preliminary qualitative LIBS analysis of five soil samples and one sewage sludge sample has allowed the detection of a number of elements including Al, Ca, Cr, Cu, Fe, Mg, Mn, Pb, Si, Ti, V and Zn. Of these, a quantitative analysis was also possible for the elements Cr, Cu, Pb, V and Zn based on the obtained linearity of the calibration curves constructed for each heavy metal, i.e., the proportionality between the intensity of the LIBS emission peaks and the concentration of each heavy metal in the sample measured by ICP. In particular, a triplet of emission lines for Cr could be used for its quantitative measurement. The consistency of experiments made on various samples was supported by the same characteristics of the laser-induced plasma (LIP), i.e., the typical linear distribution confirming the existence of local thermodynamic equilibrium (LTE) condition, and similar excitation

  16. Ontogeny of calbindin immunoreactivity in the human hippocampal formation with a special emphasis on granule cells of the dentate gyrus.

    PubMed

    Abrahám, Hajnalka; Veszprémi, Béla; Kravják, András; Kovács, Krisztina; Gömöri, Eva; Seress, László

    2009-04-01

    Calbindin (CB) is a calcium-binding protein that is present in principal cells as well as in interneurons of the hippocampal formation of various species including humans. Studies with transgenic mice revealed that CB is essential for long-term potentiation and synaptic plasticity which are the cellular basis of learning and memory. In a previous study we have shown that CB expression in granule cells of the dentate gyrus correlates with the functional maturation of the hippocampal formation in the rat. In the present study we examined the ontogeny of CB using immunohistochemistry in the human hippocampal formation paying special attention to the granule cells of the dentate gyrus. As early as the 14(th) week of gestation (GW), CB was being expressed by pyramidal cells of CA1-3 regions in the deepest cell rows of the pyramidal layer towards the ventricular zone. Later, CB sequentially appears in more superficial cell rows. After midgestation, CB disappears from CA3 pyramidal neurons. Expression of CB by granule cells starts at the 22(nd)-23(rd) GW, first by the most superficial neurons of the ectal end of the dorsal blade. At the 24(th) GW, CB is expressed by granule cells of the crest and medial portion of the ventral blade whereas later the entire ventral blade revealed CB immunoreactivity. At term, and in the first few postnatal months, CB-immunoreaction is detected in granule cells of both blades except for those neurons in the deepest cell rows at the hilar border. At around 2-3 years of age, all granule cells of the entire cell layer are CB-immunoreactive. Axons of granule cells, the mossy fibers, start to express CB around the 30(th) GW in stratum lucidum of CA3a. With further development, CB is expressed in CA3b and c, as well as in the hilus. An adult-like pattern of CB-immunoreactivity could be observed at 11 years of age. Our results indicate that (i) CB is expressed by hippocampal pyramidal cells a few weeks before midgestation; (ii) similarly to

  17. Forensic child abuse evaluation: a review.

    PubMed

    Laraque, Danielle; DeMattia, Amy; Low, Christine

    2006-12-01

    This review discusses the forensic medical and psychological assessments of children and adolescents suspected of being victims of sexual or physical abuse/neglect. Evaluation of the whole child and the need to minimize trauma during the investigative and assessment processes are stressed. The forensic medical examination is reviewed, including the specifics of the pediatric anogenital examination. The key components of the forensic medical examination in sexual assault cases are also reviewed, with particular attention to maintaining the integrity of the process. Special emphasis is placed on the forensic interview in child sexual abuse cases, the best evidence available and areas in need of further research.

  18. Understanding the Impact of Sexual Abuse. Fostering Families. A Specialized Training Program Designed for Foster Care Workers & Foster Care Parents.

    ERIC Educational Resources Information Center

    Schatz, Mona Struhsaker; Hartzell, Wenda

    This module is part of a training program for foster parents and foster care workers offered at Colorado State University. The module describes what sexual abuse is, why sexual abuse occurs, and how counties report and investigate cases of alleged sexual abuse. The module's learning objectives address: (1) ways of improving the child placement and…

  19. The Preliminary Evaluation of a Program To Help Educators Address the Substance Use/Prevention Need of Special Students.

    ERIC Educational Resources Information Center

    Demers, Jacques; French, Deanne C.; Moore, Dennis

    2000-01-01

    In pilot study, special education teachers were exposed to experiences designed to enhance their skills in adapting substance abuse prevention activities and materials for their students. Although pilot students noted an increase in their teachers' emphasis on substance abuse prevention and their criterion-related attitudes/behaviors improved…

  20. Risk evaluation and mitigation strategies for drugs with abuse liability: public interest, special interest, conflicts of interest, and the industry perspective.

    PubMed

    Wright, Curtis; Schnoll, Sidney; Bernstein, David

    2008-10-01

    Risk evaluation and mitigation strategies (REMS) formerly known as Risk Minimization Action Plans (RiskMAPs) are a regulatory technique for dealing with anticipated risks of new medications and are especially important for new drugs with abuse potential. This paper describes the origin and history of risk-management plans for drugs that might be abused, the proper use of these plans in minimizing the risk to the public, and the special difficulties inherent in managing risks for drugs with abuse potential. Drugs with abuse liability are distinctive since the risks inherent in manufacture and distribution include not only risks to patients prescribed the medications, but also risks to the general public including subgroups in the population not intended to get the drug and who receive no medical benefit from the medication. The crafting of risk-management plans intended to protect nonpatient populations is unique for these products. The content, extent, and level of intensity of these plans affect areas of medical ethics, civil liability, and criminal prosecution. The need for risk-management plans for drugs with abuse liability can potentially act as a deterrent to investment and is a factor in decisions concerning the development of new medications for the treatments of pain, ADHD, anxiety disorders, and addictions. This paper provides a framework for moving the process of REMS development forward and criteria for evaluating the probity and adequacy of such programs.

  1. Clear Cell Atypical Fibroxanthoma: Clinicopathological Study of 6 Cases and Review of the Literature With Special Emphasis on the Differential Diagnosis.

    PubMed

    Tardío, Juan C; Pinedo, Fernando; Aramburu, José Antonio; Martínez-González, Miguel Á; Arias, Dolores; Khedaoui, Radia; Suárez-Massa, Dolores; Santonja, Carlos

    2016-08-01

    Atypical fibroxanthoma (AFX) is an uncommon dermal-based neoplasm arising on the sun-damaged skin of elderly people. Clear cell AFX is a rare variant with only 12 cases reported until the present date, all of them as case reports, except for 1 small series of 3 cases. The authors report 6 new cases and review the literature with special emphasis on the differential diagnosis. The clear cell variant represents 5% of AFX from their files. Histopathologically, it consists of sheets of epithelioid, pleomorphic cells, intermixed with a varying number of giant multinucleated and spindle cells, the latter arranged in a fascicular pattern. All cell types predominantly exhibit a clear, microvacuolated cytoplasm with well-demarcated cell borders. The clinical and immunohistochemical features of this variant are similar to those of the classic type. Clear cell AFX must be differentiated from other cutaneous clear cell neoplasms, some of them with an aggressive clinical behavior, including clear cell melanoma, primary cutaneous and metastatic clear cell carcinomas, clear cell sarcoma, pleomorphic liposarcoma, tumor of perivascular epithelioid cells, and distinctive dermal clear cell mesenchymal neoplasm. The clinical presentation and immunohistochemical profile play a key role in the differential diagnosis.

  2. The fine structure of the midgut epithelium in a centipede, Scolopendra cingulata (Chilopoda, Scolopendridae), with the special emphasis on epithelial regeneration.

    PubMed

    Chajec, Lukasz; Sonakowska, Lidia; Rost-Roszkowska, Magdalena M

    2014-01-01

    Scolopendra cingulata has a tube-shaped digestive system that is divided into three distinct regions: fore-, mid- and hindgut. The midgut is lined with a pseudostratified columnar epithelium which is composed of digestive, secretory and regenerative cells. Hemocytes also appear between the digestive cells of the midgut epithelium. The ultrastructure of three types of epithelial cells and hemocytes of the midgut has been described with the special emphasis on the role of regenerative cells in the protection of midgut epithelium. The process of midgut epithelium regeneration proceeds due to the ability of regenerative cells to proliferate and differentiate according to a circadian rhythm. The regenerative cells serve as unipotent stem cells that divide in an asymmetric manner. Additionally, two types of hemocytes have been distinguished among midgut epithelial cells. They enter the midgut epithelium from the body cavity. Because of the fact that numerous microorganisms occur in the cytoplasm of midgut epithelial cells, we discuss the role of hemocytes in elimination of pathogens from the midgut epithelium. The studies were conducted with the use of transmission electron microscope and immunofluorescent methods.

  3. Introduction to the special issue: 50th anniversary of APA Division 28: The past, present, and future of psychopharmacology and substance abuse.

    PubMed

    Stoops, William W; Sigmon, Stacey C; Evans, Suzette M

    2016-08-01

    This is an introduction to the special issue "50th Anniversary of APA Division 28: The Past, Present, and Future of Psychopharmacology and Substance Abuse." Taken together, the scholarly contributions included in this special issue serve as a testament to the important work conducted by our colleagues over the past five decades. Division 28 and its members have advanced and disseminated knowledge on the behavioral effects of drugs, informed efforts to prevent and treat substance abuse, and influenced education and policy issues more generally. As past and current leaders of the division, we are excited to celebrate 50 years of Division 28 and look forward to many more successful decades for our division and its members. (PsycINFO Database Record

  4. Drinking, Drugs & Youth: Use and Abuse. Fostering Families. A Specialized Training Program Designed for Foster Care Workers & Foster Care Parents.

    ERIC Educational Resources Information Center

    Schatz, Mona Struhsaker; And Others

    This module is part of a training program for foster parents and foster care workers offered at Colorado State University. The module examines substance abuse by children aged 10 years and above. The module's learning objectives address: (1) family rules and coping mechanisms relevant to substance-abusing youth; (2) characteristics of adolescent…

  5. Drug Abuse in Southeast Asia.

    ERIC Educational Resources Information Center

    Scorzelli, James F.

    This report examines the incidence of drug abuse and the methods of treatment and prevention of drug abuse used in Southeast Asia. Countries studied include Malaysia, Singapore, Thailand, Indonesia, and the Philippines. Because of Malaysia's intensive effort to eliminate its drug abuse problem, emphasis is placed on this country's treatment and…

  6. Twenty-six-week oral toxicity of diheptyl phthalate with special emphasis on its induction of liver proliferative lesions in male F344 rats.

    PubMed

    Nakane, Fumiyuki; Kunieda, Masaki; Shimizu, Shigekazu; Kobayashi, Yoshihiko; Akane, Hirotoshi; Akie, Yasuki; Saito, Akemi; Noguchi, Masayoshi; Kadota, Toshihito; Mitsumori, Kunitoshi

    2012-01-01

    The 26-week oral toxicity of diheptyl phthalate (DHP), a peroxisome proliferator-activated receptor α (PPARα) agonist, with special emphasis on the potential induction of hepatocellular proliferative lesions was investigated in this study. DHP was administered to male F344 rats via gavage at 0 (control), 1,000 or 2,000 mg/kg/day for 26 weeks. Body weight gain was significantly lower, whereas food and water consumption was significantly higher in DHP-treated rats compared with controls. DHP-treated rats exhibited decreases in blood triglyceride, total cholesterol, phospholipid and glucose levels, which were likely related to biological effects of the PPARα agonist. Absolute and relative organ weights of the livers with pale brown discoloration and dark brown spots significantly increased in DHP-treated rats. Histopathological examinations revealed remarkable diffuse hypertrophy of hepatocytes with ground-glass appearance, intracytoplasmic inclusion bodies and/or vacuolation in the DHP-treated groups. These findings were associated with increases in serum aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, and γ-glutamyltranspeptidase. The number and area of glutathione S-transferase placental form positive foci, a marker of hepatocellular preneoplastic lesions in rats, significantly increased in DHP-treated groups. Additionally, proliferating cell nuclear antigen positive liver cell counts in DHP-treated groups were significantly higher than those of the controls. Testicular alterations were not detected histopathologically, whereas absolute and relative prostate weights significantly decreased at both doses. These results indicate that DHP induces liver pre-neoplastic foci, and suggest the possibility that DHP is a possible genotoxic carcinogen in the liver of rats.

  7. Development of neurons and fibers containing calcium binding proteins in the pallial amygdala of mouse, with special emphasis on those of the basolateral amygdalar complex.

    PubMed

    Legaz, Isabel; Olmos, Luis; Real, M Angeles; Guirado, Salvador; Dávila, José Carlos; Medina, Loreta

    2005-08-08

    We studied the development of neurons and fibers containing calbindin, calretinin, and parvalbumin in the mouse pallial amygdala, with special emphasis on those of the basolateral amygdalar complex. Numerous calbindin-immunoreactive (CB+) cells were observed in the incipient basolateral amygdalar complex and cortical amygdalar area from E13.5. At E16.5, CB+ cells became more abundant in the lateral and basolateral nuclei than in the basomedial nucleus, showing a pattern very similar to that of gamma-aminobutyric acid (GABA)ergic neurons. Many CB+ cells observed in the pallial amygdala appeared to originate in the anterior entopeduncular area/ganglionic eminences of the subpallium. The density of CB+ cells gradually increased in the pallial amygdala until the first postnatal week and appeared to decrease later, coinciding with the postnatal appearance of parvalbumin cells and raising the possibility of a partial phenotypic shift. Calretinin (CR) immunoreactivity could be observed in a few cells and fibers in the pallial amygdala at E14.5, and by E16.5 it became a good marker of the different nuclei of the basolateral amygdalar complex. Numerous CB+ and CR+ varicosities, part of which have an intrinsic origin, were observed in the basolateral amygdalar complex from E16.5, and some surrounded unstained perikarya and/or processes before birth, indicating an early formation of inhibitory networks. Each calcium binding protein showed a distinct spatiotemporal expression pattern of development in the mouse pallial amygdala. Any alteration in the development of neurons and fibers containing calcium binding proteins of the pallial amygdala may result in important disorders of emotional and social behavior.

  8. Elder Abuse and Substance Abuse

    MedlinePlus

    ... to: What is Elder Abuse? Elder Abuse and Substance Abuse Substance abuse has been identified as the most frequently cited ... victim and/or the perpetrator who has the substance abuse problem. Substance abuse is believed to be a ...

  9. Co-Occurrence of Intimate Partner Violence and Child Abuse in Hong Kong Chinese Families

    ERIC Educational Resources Information Center

    Chan, Ko Ling

    2011-01-01

    This study examines the prevalence of co-occurrence of intimate partner violence (IPV) and child abuse and neglect (CAN) in a cohort of Chinese parents drawn from a large representative sample in Hong Kong. It also investigates the risk factors for CAN with a special emphasis on the role of IPV. A subsample of 2,363 parents was invited to complete…

  10. Organization of the dorsocaudal neostriatal complex: a retrograde and anterograde tracing study in the domestic chick with special emphasis on pathways relevant to imprinting.

    PubMed

    Metzger, M; Jiang, S; Braun, K

    1998-06-08

    In the forebrain of domestic chicks, a network of distinct regions is crucially involved in auditory and visual filial imprinting. Among these areas, a distinct part of the dorsocaudal neostriatal complex (dNC complex), termed neostriatum dorsocaudale (Ndc), was recently discovered by its enhanced metabolic activity during the presentation of auditory and visual imprinting stimuli. Since there is evidence that the dNC complex consists of several distinct functional subareas, we investigated the neural connections of different parts of the dNC complex by retro- and anterograde pathway tracing. Special emphasis was put on the connections of the dNC complex with other imprinting relevant regions in the rostral telencephalon, such as the mediorostral neostriatum/hyperstriatum ventrale (MNH) and the intermediate and medial part of the hyperstriatum ventrale (IMHV). By anterograde and multiple retrograde pathway tracing, we found that the dNC complex may at least be subdivided into three major constituents. The most medial part of the dNC complex, termed neostriatum dorsale (Nd), is characterized by strong reciprocal connections with the neostriatal part of the MNH and by its auditory related inputs, including those from the output layers L1 and L3 of field L, and the shell region of the thalamic n. ovoidalis. The Ndc, which occupies the central aspects of the dNC complex, is mainly characterized by reciprocal connections with the ectostriatal belt (Ep) and the adjacent neostriatum (N). Furthermore, Nd and Ndc receive strong thalamic input from the n. dorsolateralis posterior (DLP), both project to the IMHV, and both are reciprocally connected with the archistriatum intermedium (AI). The most lateral aspect of the dNC complex, termed Ndl, is characterized by afferents from the neostriatum frontale, pars trigeminalis (NFT), and by the lack of a thalamic input. Results indicate that the dNC complex comprises distinct subregions, which are characterized by their specific

  11. Responding to Pacific Islanders: Culturally Competent Perspectives for Substance Abuse Prevention. CSAP Cultural Competence Series 8. Special Collaborative Edition.

    ERIC Educational Resources Information Center

    Mokuau, Noreen; Kameoka, Velma A.; Kupuna, Abbie Napeahi; Kelly, Terry; Burgess, Paula-Ann; Kamiyama, David; Young, Kawen T.; Galea'i, Kenneth Elifasa; Natividad, Lisalinda; Dobbin, Jay; Oneisom, Innocente; Mason, Michael

    This monograph addresses issues of concern to primary health care practitioners, policy makers, and evaluators wishing to broaden access to quality substance abuse prevention services for Pacific Islanders. It is devoted exclusively to health issues affecting Pacific Islanders, who often lack access to comprehensive health care because of…

  12. Psychosocial aspects of chronic pelvic pain, with special reference to sexual abuse. A study of 164 women.

    PubMed Central

    Fry, R. P.; Crisp, A. H.; Beard, R. W.; McGuigan, S.

    1993-01-01

    Patients with chronic pelvic pain attending a tertiary referral centre show certain social, developmental and psychological characteristics. Specifically, they appear to have fewer children and to report more paternal overprotection, and a trend towards low maternal care compared to normals. They also show more depression, free-floating anxiety and somatic anxiety than such populations. The levels are similar to those found in other outpatient populations presenting with migraine or irritable bowel syndrome. Hostility levels are greater than those in normal subjects. Overall the present patient population reports the same degree of childhood sexual abuse as do many other female clinic and community sample populations. Sexual abuse is unlikely to be a specific aetiological factor in the development of chronic pelvic pain though it may yet be found to be important in subsets of the population. PMID:8415346

  13. Correlates of improvement in substance abuse among dually diagnosed veterans with post-traumatic stress disorder in specialized intensive VA treatment.

    PubMed

    Coker, Kendell L; Stefanovics, Elina; Rosenheck, Robert

    2016-01-01

    Substantial rates of substance use comorbidity have been observed among veterans with Post-Traumatic Stress Disorder (PTSD), highlighting the need to identify patient and program characteristics associated with improved outcomes for substance abuse. Data were drawn from 12,270 dually diagnosed veterans who sought treatment from specialized intensive Veterans Health Administration PTSD programs between 1993 and 2011. The magnitude of the improvement in Addiction Severity Index (ASI) alcohol and drug use composite scores from baseline was moderate, with effect sizes (ES) of -.269 and -.287, respectively. Multivariate analyses revealed that treatment in longer-term programs, being prescribed psychiatric medication, and planned participation in reunions were all associated with slightly improved outcomes. Reductions in substance use measures were associated with robust improvements in PTSD symptoms and violent behavior. These findings suggest not only synergistic treatment effects linking improvement in PTSD symptoms with substance use disorders among dually diagnosed veterans with PTSD, but also to reductions in violent behavior. Furthermore, the findings indicate that proper discharge planning in addition to intensity and duration of treatment for dually diagnosed veterans with severe PTSD may result in better outcomes. Further dissemination of evidence-based substance abuse treatment may benefit this population.

  14. Introduction to the Special Issue “Pharmacotherapies for the Treatment of Alcohol Abuse and Dependence” and a Summary of Patents Targeting other Neurotransmitter Systems

    PubMed Central

    Bell, Richard L.; Franklin, Kelle M.; Hauser, Sheketha R.; Zhou, Feng C.

    2013-01-01

    This paper introduces the Special Section: Pharmacotherapies for the Treatment of Alcohol Abuse and Dependence and provides a summary of patents targeting neurotransmitter systems not covered in the other four chapters. The World Health Organization notes that alcoholic-type drinking results in 2.5 million deaths per year, and these deaths occur to a disproportionately greater extent among adolescents and young adults. Developing a pharmacological treatment targeting alcohol abuse and dependence is complicated by (a) the heterogeneous nature of the disease(s), (b) alcohol affecting multiple neurotransmitter and neuromodulator systems, and (c) alcohol affecting multiple organ systems which in turn influence the function of the central nervous system. Presently, the USA Federal Drug Administration has approved three pharmacotherapies for alcoholism: disulfiram, naltrexone, and acamprosate. This chapter provides a summary of the following systems, which are not covered in the accompanying chapters; alcohol and acetaldehyde metabolism, opioid, glycinergic, GABA-A, neurosteroid, dopaminergic, serotonergic, and endocannabinoid, as well as patents targeting these systems for the treatment of alcoholism. Finally, an overview is presented on the use of pharmacogenetics and pharmacogenomics in tailoring treatments for certain subpopulations of alcoholics, which is expected to continue in the future. PMID:22574678

  15. Problem of ticks and tick-borne diseases in India with special emphasis on progress in tick control research: a review.

    PubMed

    Ghosh, Srikant; Nagar, Gaurav

    2014-12-01

    Ticks, as vectors of several zoonotic diseases, are ranked second only to mosquitoes as vectors. The diseases spread by ticks are a major constraint to animal productivity while causing morbidity and mortality in both animals and humans. A number of tick species have been recognised since long as vectors of lethal pathogens, viz. Crimean-Congo haemorrhagic fever virus (CCHFV), Kyasanur forest disease virus (KFDV), Babesia spp, Theileria, Rickettsia conorii, Anaplasma marginale, etc. and the damages caused by them are well-recognised. There is a need to reassess the renewed threat posed by the tick vectors and to prioritize the tick control research programme. This review is focused on the major tick-borne human and animal diseases in India and the progress in vector control research with emphasis on acaricide resistance, tick vaccine and the development of potential phytoacaricides as an integral part of integrated tick control programme.

  16. Exercise rehabilitation for peripheral artery disease: An exercise physiology perspective with special emphasis on the emerging trend of home-based exercise.

    PubMed

    Gardner, Andrew W

    2015-11-01

    Peripheral artery disease (PAD) is a significant medical concern that is highly prevalent, costly, and deadly. Additionally, patients with PAD have significant impairments in functional independence and health-related quality of life due to leg symptoms and ambulatory dysfunction. Exercise therapy is a primary treatment for patients with PAD, as ambulatory outcome measures improve following a program of exercise rehabilitation. This review describes the outcomes that improve with exercise, the potential mechanisms for improved leg symptoms, key exercise program considerations for training patients with PAD with walking-based exercise, other exercise modalities that have been utilised, the use of on-site supervised exercise programs, and a major focus on historical and contemporary trials on conducting home-based, minimally supervised exercise program to treat PAD. The review concludes with recommendations for future exercise trials, with particular emphasis on reported greater details of the exercise prescription to more accurately quantify the total exercise dose of the program.

  17. Genetic characterization and phylogenetic analysis of skunk-associated rabies viruses in North America with special emphasis on the central plains.

    PubMed

    Davis, Rolan; Nadin-Davis, Susan A; Moore, Michael; Hanlon, Cathleen

    2013-06-01

    Across North America the skunk acts as a reservoir for several rabies virus variants. Some of these variants are geographically restricted in range as is the case for the California skunk variant and two distinct variants present in Mexico. In contrast the North Central and South Central skunk rabies viruses are dispersed in overlapping ranges over large areas of the Midwestern region of the United States with the former extending into southern parts of the Canadian prairies. Despite this extensive range, there has been only very limited molecular characterization of these two viral variants. This study has examined the genetic diversity of the rabies viruses associated with North American skunks, with particular emphasis on the South Central skunk variant which was found to comprise three distinct geographically restricted groups of viruses that could in some cases be further sub-divided. The phylogenetic relationships of these groups and sub-groups allowed us to infer the likely direction of spread of these variants in some instances. Patterns of amino acid replacement of North American skunk-associated rabies viruses for both the nucleoprotein and glycoprotein products are also examined. These patterns reflect the virus phylogeny but no amino acid residues associated specifically with the skunk host were identified.

  18. Spectrum of Sickle Cell Diseases in Patients Diagnosed at a Tertiary Care Centre in Karnataka with Special Emphasis on their Clinicohaematological Profile

    PubMed Central

    Lokanatha, Hemalata; Ramachandrappa, Rajashekar Murthy G

    2016-01-01

    Introduction Sickle cell disease is a monogenic disorder with considerable clinical diversity and Sickle haemoglobin is responsible for wide spectrum of disorders which vary with respect to severity of anaemia, frequency of crises and duration of survival. As they are confused with many other clinically aggressive disorders, precision in diagnosis is essential both to proper clinical management and subsequent genetic counselling. Hence, this study was taken up in order to diagnose these conditions and administer suitable counselling measures to minimise the incidence of sickle cell disease in the future. Aim The aim of this study was to identify the spectrum of all Sickle cell diseases diagnosed at a tertiary care centre in Bangalore, Karnataka, India who presented over a period of five years from 2009 to 2013 and also to screen the parents and siblings of the patients for their carrier status. Materials and Methods We reviewed 26 cases of Sickle Cell Disease (SCD) and also 38 parents & 10 siblings of these children for their carrier status. Haemoglobin electrophoreses was performed by using alkaline gel method, followed by High Performance Liquid Chromatography when needed. Results A total of 26 children diagnosed with SCD were enrolled in the study. Most common entity was Sickle Cell Anaemia (SCA), followed by sickle thalassaemia and Sickle Cell Trait (SCT). Commonest clinical presentation was fever and pallor. Amongst the parents and siblings, sickle cell trait was the most common entity followed by thalassaemia trait. One interesting case of HbSE disease was encountered, which is a rare entity in India. Conclusion This study brings out the total spectrum of SCDs in a tertiary care centre in Karnataka, with more emphasis on screening of the parents and siblings for their carrier status. PMID:27042470

  19. Elder Abuse

    MedlinePlus

    ... mistreatment may be Physical, sexual, or emotional abuse Neglect or abandonment Financial abuse - stealing of money or belongings Possible signs of elder abuse include unexplained bruises, burns, and injuries. There ...

  20. Child Abuse

    MedlinePlus

    ... or puts a child at risk of harm. Child abuse can be physical, sexual or emotional. Neglect, or not providing for a child's needs, is also a form of abuse. Most abused children suffer greater emotional than physical ...

  1. Drug Abuse

    MedlinePlus

    ... abuse also plays a role in many major social problems, such as drugged driving, violence, stress, and child abuse. Drug abuse can lead to homelessness, crime, and missed work or problems with keeping a ...

  2. The Academic Consequences of Substance Use and Abuse among Adolescent Males in High School: Implications for Assessment and Intervention for Special Education Students

    ERIC Educational Resources Information Center

    Gomez-Cerrillo, Lino

    2012-01-01

    The problem of middle adolescent substance use and abuse among high school age males was examined. Financial and socio-emotional costs and rates of incidence for substance use and abuse among high school males are addressed followed by a discussion of social, environmental, and intra-psychic factors, which influence substance use and abuse. To…

  3. 26 CFR 301.6231(c)-2 - Special rules for certain refund claims based on losses, deductions, or credits from abusive tax...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... on losses, deductions, or credits from abusive tax shelter partnerships. 301.6231(c)-2 Section 301... for certain refund claims based on losses, deductions, or credits from abusive tax shelter... (relating to penalty for promoting abusive tax shelters, etc.). This section applies only with respect to...

  4. 26 CFR 301.6231(c)-2 - Special rules for certain refund claims based on losses, deductions, or credits from abusive tax...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... on losses, deductions, or credits from abusive tax shelter partnerships. 301.6231(c)-2 Section 301... for certain refund claims based on losses, deductions, or credits from abusive tax shelter... (relating to penalty for promoting abusive tax shelters, etc.). This section applies only with respect to...

  5. 26 CFR 301.6231(c)-2 - Special rules for certain refund claims based on losses, deductions, or credits from abusive tax...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... on losses, deductions, or credits from abusive tax shelter partnerships. 301.6231(c)-2 Section 301... for certain refund claims based on losses, deductions, or credits from abusive tax shelter... (relating to penalty for promoting abusive tax shelters, etc.). This section applies only with respect to...

  6. 26 CFR 301.6231(c)-2 - Special rules for certain refund claims based on losses, deductions, or credits from abusive tax...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... on losses, deductions, or credits from abusive tax shelter partnerships. 301.6231(c)-2 Section 301... for certain refund claims based on losses, deductions, or credits from abusive tax shelter... (relating to penalty for promoting abusive tax shelters, etc.). This section applies only with respect to...

  7. 26 CFR 301.6231(c)-2 - Special rules for certain refund claims based on losses, deductions, or credits from abusive tax...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... on losses, deductions, or credits from abusive tax shelter partnerships. 301.6231(c)-2 Section 301... for certain refund claims based on losses, deductions, or credits from abusive tax shelter... (relating to penalty for promoting abusive tax shelters, etc.). This section applies only with respect to...

  8. A survey on regenerative surgery performed by Swiss specialists in periodontology with special emphasis on the application of enamel matrix derivatives in infrabony defects.

    PubMed

    Schröen, Ola; Sahrmann, Philipp; Roos, Malgorzata; Attin, Thomas; Schmidlin, Patrick R

    2011-01-01

    This survey aimed to evaluate the common practice of regenerative periodontal surgery with special regard to the use of enamel matrix derivatives (EMD, Emdogain® ) by board-certified specialists in periodontology and non-certified, but active members of the Swiss Society of Periodontology (SSP). A cross-sectional postal survey of 533 dentists, representing all members of the SSP practising in Switzerland, was conducted. The questionnaire consisted of three sections, assessing: 1) general personal information regarding the practice setting and education, 2) general questions regarding periodontal surgery practices and 3) specific questions regarding the use of EMD. The information obtained was compared and differences between specialists and non-specialists were calculated. P-values smaller than 5% were considered significant. Sixty-nine percent of the specialists answered the questionnaire, compared to only 37.4% of the non-specialists (overall: 42.4%). In general, specialists performed surgeries more frequently, and presented a significantly higher percentage of EMD users than the non-specialists. The application guidelines were followed in general. Some differences were observed in application and selection criteria. The subjective perception of clinical success varied greatly among clinicians. Residual pockets were reported to be present in approximately one third of the defects after therapy. In conclusion, this survey revealed that EMD was used on a regular basis by dentists performing periodontal therapy. In addition, the answers by both groups generally corresponded well with the current available literature.

  9. Differential diagnosis of adrenal mass using imaging modality: special emphasis on f-18 fluoro-2-deoxy-d-glucose positron emission tomography/computed tomography.

    PubMed

    Lee, Hong Je; Lee, Jaetae

    2014-03-01

    Adrenal incidentalomas are adrenal masses serendipitously detected during an imaging study performed for reasons unrelated to suspicion of adrenal disease. The incidence of adrenal incidentalomas has increased because of the widespread use of various imaging modalities. In oncology patients with adrenal incidentalomas, the characterization of the adrenal masses is challenging because nearly 50% of incidental adrenal masses are metastatic lesions that need special medical attention. Although unenhanced computed tomography (CT) densitometry, chemical shift magnetic resonance imaging (MRI), delayed contrast-enhanced CT and CT histogram analysis have been used as sensitive and specific modalities for differentiating benign from malignant adrenal masses, F-18 fluoro-2-deoxy-D-glucose positron emission tomography (F-18 FDG PET)/CT is a highly accurate imaging modality compared to CT or MRI, especially when these two imaging modalities are combined. In addition, a semiquantitative analysis using standardized uptake value ratio further improves the diagnostic accuracy of F-18 FDG PET/CT in differentiating benign from malignant adrenal masses. Thus, F-18 FDG PET/CT is very helpful for determining the best therapeutic management, especially for assessing the need for surgery.

  10. Probing the mystery of Chinese medicine meridian channels with special emphasis on the connective tissue interstitial fluid system, mechanotransduction, cells durotaxis and mast cell degranulation

    PubMed Central

    Fung, Peter Chin Wan

    2009-01-01

    This article hypothesizes that the Chinese medicine meridian system is a special channel network comprising of skin with abundant nerves and nociceptive receptors of various types, and deeper connective tissues inside the body with the flowing interstitial fluid system. These meridian channels provide efficient migratory tracks mainly due to durotaxis (also including chemotaxis) for mast cells, fibroblasts and other cells to migrate and carry out a number of physiological functions. Acupuncture acting on meridian channel causes cytoskeletal remodeling through mechanotransduction, leading to regulation of gene expression and the subsequent production of related proteins. Also, stimulation on cell surface can trigger Ca2+ activities, resulting in a cascade of intra- and inter-cellular signaling. Moreover, nerve endings in the meridian channels interact with mast cells and induce the degranulation of these cells, leading to the release of many specific biomolecules needed for homeostasis, immune surveillance, wound healing and tissue repair. Acupoint along a meridian channel is a functional site to trigger the above functions with specificity and high efficiency. PMID:19480699

  11. Distribution of immunoreactive glutamine synthetase in the adult human and mouse brain. Qualitative and quantitative observations with special emphasis on extra-astroglial protein localization.

    PubMed

    Bernstein, Hans-Gert; Bannier, Jana; Meyer-Lotz, Gabriela; Steiner, Johann; Keilhoff, Gerburg; Dobrowolny, Henrik; Walter, Martin; Bogerts, Bernhard

    2014-11-01

    Glutamine synthetase catalyzes the ATP-dependent condensation of ammonia and glutamate to form glutamine, thus playing a pivotal role in glutamate and glutamine homoeostasis. Despite a plethora of studies on this enzyme, knowledge about the regional and cellular distribution of this enzyme in human brain is still fragmentary. Therefore, we mapped fourteen post-mortem brains of psychically healthy individuals for the distribution of the glutamine synthetase immunoreactive protein. It was found that glutamine synthetase immunoreactivity is expressed in multiple gray and white matter astrocytes, but also in oligodendrocytes, ependymal cells and certain neurons. Since a possible extra-astrocytic expression of glutamine synthetase is highly controversial, we paid special attention to its appearance in oligodendrocytes and neurons. By double immunolabeling of mouse brain slices and cultured mouse brain cells for glutamine synthetase and cell-type-specific markers we provide evidence that besides astrocytes subpopulations of oligodendrocytes, microglial cells and neurons express glutamine synthetase. Moreover, we show that glutamine synthetase-immunopositive neurons are not randomly distributed throughout human and mouse brain, but represent a subpopulation of nitrergic (i.e. neuronal nitric oxide synthase expressing) neurons. Possible functional implications of an extra-astrocytic localization of glutamine synthetase are discussed.

  12. Mortality and morbidity in the city of Bern, Switzerland, 1805-1815 with special emphasis on infant, child and maternal deaths.

    PubMed

    Rüttimann, D; Loesch, S

    2012-02-01

    This article contributes to the research on demographics and public health of urban populations of preindustrial Europe. The key source is a burial register that contains information on the deceased, such as age and sex, residence and cause of death. This register is one of the earliest compilations of data sets of individuals with this high degree of completeness and consistency. Critical assessment of the register's origin, formation and upkeep promises high validity and reliability. Between 1805 and 1815, 4,390 deceased inhabitants were registered. Information concerning these individuals provides the basis for this study. Life tables of Bern's population were created using different models. The causes of death were classified and their frequency calculated. Furthermore, the susceptibility of age groups to certain causes of death was established. Special attention was given to causes of death and mortality of newborns, infants and birth-giving women. In comparison to other cities and regions in Central Europe, Bern's mortality structure shows low rates for infants (q0=0.144) and children (q1-4=0.068). This could have simply indicated better living conditions. Life expectancy at birth was 43 years. Mortality was high in winter and spring, and decreased in summer to a low level with a short rise in August. The study of the causes of death was inhibited by difficulties in translating early 19th century nomenclature into the modern medical system. Nonetheless, death from metabolic disorders, illnesses of the respiratory system, and debilitation were the most prominent causes in Bern. Apparently, the worst killer of infants up to 12 months was the "gichteren", an obsolete German term for lethal spasmodic convulsions. The exact modern identification of this disease remains unclear. Possibilities such as infant tetanus or infant epilepsy are discussed. The maternal death rate of 0.72% is comparable with values calculated from contemporaneous sources. Relevance of

  13. Mental health care in post-genocide Rwanda: evaluation of a program specializing in posttraumatic stress disorder and substance abuse

    PubMed Central

    Ng, L. C.; Harerimana, B.

    2016-01-01

    Background Following the genocide, millions of Rwandans are likely living with posttraumatic stress disorder (PTSD). Le Centre Psychothérapeutique Icyizere provides the only specialized treatment for PTSD in the Rwandan healthcare system. Methods Demographics, diagnosis, treatment, outcomes, and scores on assessments of functioning and PTSD were recorded from clinical charts of all patients receiving care between October 2013 and 2014. Descriptive statistics and within-group t tests comparing functional impairment and PTSD symptoms at intake to discharge and follow-up were calculated. Results A total of 719 patients (55.08% male) received care. Patients were more educated, more likely to live in the capital, and less likely to be married than the general population. Patients reported high desire for, and strong satisfaction with, care. Most patients (55.60%) were still in care by the end of the program evaluation. Functioning improved from intake to discharge (p < 0.001), and improvements were sustained at follow-up (p < 0.001). Most adults were diagnosed with psychotic disorders, substance use disorders, or depression. Only 20 patients were diagnosed with PTSD, and symptoms were improved at discharge (p = 0.003). Conclusions This program evaluation demonstrated the utility of a low-resource information management system to provide clarity about the patient population and outcomes. Results suggest that services are effective and sustainable, although people with PTSD were not the primary recipients of care. Disparities in care by diagnosis, education, marital status, and geography are discussed. Results have contributed to changes in service delivery and care and efforts to increase access to care. PMID:27610238

  14. Recognizing abuse.

    PubMed

    Davidhizar, R; Newman-Giger, J

    1996-01-01

    After years as a taboo topic, abuse has come "out of the closet" and is being talked about openly in society. Yet, while abuse in the workplace is being confronted, abuse within families still often goes unrecognized by outsiders, including by nurses. Failure of nurses to recognize abuse is unfortunate since frequently they are the first point of contact with the victim of abuse in the emergency room, clinic and home. Understanding and insight into the problem of family violence by nurses is critical in addressing this problem. Knowledge is crucial in planning strategies that will have the long-lasting effect of decreasing the cycle of abuse in families.

  15. Physical Abuse

    MedlinePlus

    ... seniors who are not abused. What are the indicators? Indicators are signs or clues that abuse has ... clusters of indicators that suggest a problem. Physical indicators Sprains, dislocations, fractures, or broken bones Burns from ...

  16. Inhalant Abuse

    MedlinePlus

    ... Who may be abusing inhalants?The most common abusers of inhalants are teenagers, especially those who are ... to your child about the dangers of trying drugs can help him or her make the right ...

  17. Abusive Relationships

    MedlinePlus

    ... relationships and friendships. Emotional abuse (stuff like teasing, bullying, and humiliating others) can be difficult to recognize ... How to Break Up Respectfully Abuse Dealing With Bullying Date Rape Getting Over a Break-Up Posttraumatic ...

  18. Adolescent Abuse.

    ERIC Educational Resources Information Center

    Foreman, Susan; Seligman, Linda

    1983-01-01

    Discusses legal and developmental aspects of adolescent abuse, as distinguished from child abuse. The role of the school counselor in identifying and counseling abused adolescents and their families is discussed and several forms of intervention and support services are described. (JAC)

  19. Abused and Traumatized Children.

    ERIC Educational Resources Information Center

    Carmichael, Karla D.

    This document is a class presentation designed to present a history of child abuse and interventions for the beginning play therapist. Attempts to understand child behavior are traced back to their roots in the fields of mental retardation and special education as early as 1799 and followed through the mental health and child guidance movements of…

  20. Psycho-social Profile of Abused Children in India.

    ERIC Educational Resources Information Center

    Chowdhury, Aparajita; And Others

    1994-01-01

    Reviews the child abuse cases in India under categories based on different forms of child abuse, marital issues involved, parent child interactions, social and psychological characteristics, trends associated with the abused children, and remedial measures. Concludes with an emphasis on the need for empirical data on the extent and nature of child…

  1. Understanding and Addressing the Trauma from Abuse: A Model of Safety, Reconnection, and Integration for Victims of Abuse. A Specialized Training Program Designed To Enhance the Competency of Caseworkers, Adoptive & Foster Parents.

    ERIC Educational Resources Information Center

    Schatz, Mona Struhsaker; Rigg, Georgia A.

    Although the trauma that children experience in abusive situations differs from the trauma of a disaster, its effects are just as profound. The information and skills that caseworkers need to assess families and children who have been traumatized, to make more appropriate treatment planning decisions, and to carry out their professional roles with…

  2. NCADI's 1995 National Directory of Drug Abuse and Alcoholism Treatment and Prevention Programs That Have a Special Program for American Indians/Alaska Natives.

    ERIC Educational Resources Information Center

    Vanderbilt, Rebecca, Comp.; Schacht, Robert M., Comp.

    This state-by-state directory lists over 500 alcohol and drug abuse treatment and prevention services that target American Indians and Alaska Natives. The directory was compiled from the website of the National Clearinghouse for Alcohol and Drug Information (NCADI). Their home page on the Internet is located at http://www.health.org/index.htm. The…

  3. Alcohol and Substance Abuse: Confronting Difficult Families. A Specialized Training Program Designed To Enhance the Competency of Caseworkers, Adoptive & Foster Parents.

    ERIC Educational Resources Information Center

    Schatz, Mona Struhsaker; Denmark, Larry

    Addressing the complexities of families facing substance abuse can help caseworkers in assessment and treatment-planning activities. Some basic information and skills that caseworkers and foster care parents can use in the assessment of addiction and treatment-planning decisions are presented in this training manual. The manual and training…

  4. Child Sexual Abuse

    MedlinePlus

    ... for pornography is also sexual abuse. Most sexual abusers know the child they abuse. They may be ... friends, neighbors or babysitters. About one-third of abusers are related to the child. Most abusers are ...

  5. Fetal Abuse.

    ERIC Educational Resources Information Center

    Kent, Lindsey; And Others

    1997-01-01

    Five cases of fetal abuse by mothers suffering from depression are discussed. Four of the women had unplanned pregnancies and had considered termination of the pregnancy. Other factors associated with fetal abuse include pregnancy denial, pregnancy ambivalence, previous postpartum depression, and difficulties in relationships. Vigilance for…

  6. Methamphetamine abuse and "meth mouth".

    PubMed

    Rhodus, Nelson L; Little, James W

    2005-01-01

    Dental management for the patient who abuses drugs is always a challenge. The number of patients abusing methamphetamines appears to be increasing. The dentist needs to be aware of the clinical presentation and medical risks presented by these patients and to attempt to get the patient to seek professional help. Additionally, special attention will be necessary for the high prevalence and severity of oral manifestations including rampant caries, enamel erosion, xerostomia, bruxism, and muscle trismus.

  7. Emphasis: Teachers Doing Research.

    ERIC Educational Resources Information Center

    Knudson, Richard L., Ed.

    1975-01-01

    The emphasis of this issue, reflecting increased demand for accountability, is the importance of teachers gathering data which substantiate pupil growth and present facts about what is going on in English classrooms, especially when teachers are trying different classroom approaches. Articles also discuss student responses to literature, student…

  8. Drug abuse

    MedlinePlus

    ... 5th ed. Arlington, VA: American Psychiatric Publishing. 2013. Weiss RD. Drugs of abuse. In: Goldman L, ... Hospice and Palliative Medicine, Atlanta, GA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the ...

  9. Abusive Relationships

    MedlinePlus

    ... Break Up Respectfully Abuse Sexual Harassment and Sexual Bullying Love and Romance Getting Over a Break-Up Dealing With Bullying Posttraumatic Stress Disorder Sexual Attraction and Orientation Teens ...

  10. Emphasis in Telugu.

    PubMed

    Prabhakar Babu, B A

    1977-01-01

    The phenomenon of emphasis is studied with regard to the phonetic variation of the vowel and consonant units of the word structure in Telugu, a Dravidian language spoken mainly in South India. The electro-aerometer and the mingograph are used to provide phonetic evidence. The study reveals that different means are used to emphasise words of different structures so that the phonological structure is not disturbed.

  11. Medical Advances in Child Sexual Abuse

    ERIC Educational Resources Information Center

    Alexander, Randell A.

    2011-01-01

    This volume is the first of a two-part special issue detailing state of the art practice in medical issues around child sexual abuse. The six articles in this issue explore methods for medical history evaluation, the rationale for when sexual examinations should take place, specific hymenal findings that suggest a child has been sexually abused,…

  12. Juvenile Drug Courts and Teen Substance Abuse

    ERIC Educational Resources Information Center

    Butts, Jeffrey A., Ed.; Roman, John, Ed.

    2004-01-01

    Juvenile justice officials across the United States are embracing a new method of dealing with adolescent substance abuse. Importing a popular innovation from adult courts, state and local governments have started hundreds of specialized drug courts to provide judicial supervision and coordinate substance abuse treatment for drug-involved…

  13. Child Sexual Abuse

    MedlinePlus

    ... Enter ZIP code here Enter ZIP code here Child Sexual Abuse Public This section is for Veterans, General Public, Family, & Friends Child Sexual Abuse What is child sexual abuse? Child sexual abuse ...

  14. [Child abuse].

    PubMed

    V Essen, H; Schlickewei, W; Dietz, H-G

    2005-02-01

    Child abuse is most often diagnosed by an emergency doctor on call who sometimes "feels" more than knows what he is confronted with. He should nevertheless always take a medical history and make a physical and radiological examination. X-ray imaging and an ophthalmologic retinal examination are the most important diagnostic steps. Typical findings are multiple and/or dorsal rib fractures, complex skull fractures, physeal fractures, all fractures within the first 12 months, multiple fractures in different localisations and stages of healing, all injuries with uncommon distributions, all patterned bruises, immersion burns, intramural hematoma and every unexplained loss of consciousness. The first step towards victim protection is always the removal of the abused child from its caregivers by admitting it to hospital, as 95% of all cases of reported child abuse take place within the child's family.

  15. Positive Coping Strategies Developed by Survivors of Childhood Sexual Abuse.

    ERIC Educational Resources Information Center

    Benishek, Lois A.; Morrow, Susan L.

    1995-01-01

    Estimates indicate that 1 in 4 women and 1 in 7 men have been sexually abused as children. These statistics may be underestimated based on anecdotal information relayed by many therapists who specialize in working with survivors of childhood sexual abuse. Effects of childhood sexual abuse have far reaching implications for the survivors' abilities…

  16. Singaporean Early Childhood Teachers' Responses to Myths about Child Abuse

    ERIC Educational Resources Information Center

    Briggs, Freda; Potter, Gillian K.

    2004-01-01

    Prior to attending seminars on child abuse and domestic violence, 86 kindergarten and 64 special education (early childhood) teachers completed a questionnaire seeking views relating to the accuracy of statements relating to all forms of child abuse. This was designed to identify the accuracy of teachers' knowledge of child abuse and neglect…

  17. Sexual Abuse

    MedlinePlus

    ... bruises, while behavioral indicators are ways victims and abusers act or interact with each other. Some of the indicators listed below can be explained by other causes (e.g. inappropriate or unusual behavior may signal dementia or drug interactions) and no single indicator can be taken ...

  18. Nutritional Alterations in Drug Abusers With and Without HIV

    PubMed Central

    Forrester, Janet E.

    2007-01-01

    Many studies have found that drug abusers have nutritional deficits, including weight deficits. The most plausible explanation for these deficits is dietary insufficiency. However, studies using objective measures of the dietary intake of drug abusers have failed to provide evidence of dietary insufficiency. Other mechanisms have rarely been examined. This article reviews the published literature on the nutritional status of drug abusers with and without HIV, with emphasis on dietary energy and macronutrient intake. PMID:17356685

  19. New perspectives on the similarities and differences of alcoholism and drug abuse.

    PubMed

    Keeley, K A; Solomon, J

    1981-01-01

    This article reviews the similarities and differences of alcoholism and drug abuse from a biopsychosocial perspective. Special emphasis is given to newer developments. In biology, the role of endorphins and isoquinolines is considered against the more traditionally recognized clinical differences between alcohol and drug disorders. Consideration is given to psychological themes such as the utility of the addictive personality concept, the impact of more sophisticated prevention strategies, and the combined treatment of alcoholics and drug abusers. Reports from social fields include a cross-cultural view of chemical dependence and an appraisal of legal and political trends which influence chemical use and the civil rights of chemical users. Recent developments in the biologic, psychologic and social sciences have solidified the impression that the chemical dependencies, for all their differences, share a number of important characteristics. The etiology of alcoholism and drug abuse has been attributed to biopsychosocial causes, currently a widely accepted hypothesis. From one perspective, this theory could be seen as a grab bag approach, since no specific universal cause has been discovered while many have been postulated. From another aspect, the hypothesis is a rational synthesis of present knowledge which finds no one etiological factor to be either preeminent or ubiquitous. This article presents in succession an overview of the biology, psychology and sociology of chemical dependence with emphasis on integrating newer developments with familiar knowledge.

  20. Spousal Abuse

    PubMed Central

    Gullattee, Alyce C.

    1979-01-01

    Spouse abuse is being discussed and agonized over more frequently than in past years. Although interpousal and intrafamilial violence have been behaviors of note and considerable consequence, they have been attributable, almost exclusively, to the lower socioeconomic classes. Many hypotheses have been proposed concerning the etiology of violence. The author discusses some of the more general sociopolitical theories of violence and proposes three areas of significant moment to behaviorists. PMID:439165

  1. Child Abuse: Definition.

    ERIC Educational Resources Information Center

    Wilson, Timothy L.-Y.

    The purpose of this paper was to elaborate on the definitions of child abuse in order to improve the understanding of child abuse. The definitions given by the U.S. House Joint Committee on Child Abuse in the Child Abuse Prevention and Treatment Act, and in research by Holden (1984), are cited. These definitions refer to the nature of abusive acts…

  2. Prescription Drug Abuse

    MedlinePlus

    ... Whether they're using street drugs or medications, drug abusers often have trouble at school, at home, with ... a short period of time may make a drug abuser aggressive or paranoid. Although stimulant abuse might not ...

  3. Special session on environment and energy, and repeated emphasis from early-`80s onwards, hybrid-drive targets for penetrating beams, that encompasses ultra high intensity lasers and/or particle beams

    SciTech Connect

    Mark, J.W. ||

    1994-10-05

    In this special session, we discuss {bold global} {bold climate} {bold change} concerns, as well as {bold cleanup} {bold of} {bold wastes} {bold and}/{bold or} {bold toxic} {bold materials}, their relations to energy and other technologies. We especially bring together scientists to discuss available and/or developable technologies of amelioration or cleanup, for consideration of unusual uses of {bold Lasers}, {bold Particle} {bold Beams} {bold and} {bold other} {bold plasma} Phenomena. {copyright}{ital American} {ital Institute} {ital of} {ital Physics} 1994

  4. Specialized Science

    PubMed Central

    Fang, Ferric C.

    2014-01-01

    As the body of scientific knowledge in a discipline increases, there is pressure for specialization. Fields spawn subfields that then become entities in themselves that promote further specialization. The process by which scientists join specialized groups has remarkable similarities to the guild system of the middle ages. The advantages of specialization of science include efficiency, the establishment of normative standards, and the potential for greater rigor in experimental research. However, specialization also carries risks of monopoly, monotony, and isolation. The current tendency to judge scientific work by the impact factor of the journal in which it is published may have roots in overspecialization, as scientists are less able to critically evaluate work outside their field than before. Scientists in particular define themselves through group identity and adopt practices that conform to the expectations and dynamics of such groups. As part of our continuing analysis of issues confronting contemporary science, we analyze the emergence and consequences of specialization in science, with a particular emphasis on microbiology, a field highly vulnerable to balkanization along microbial phylogenetic boundaries, and suggest that specialization carries significant costs. We propose measures to mitigate the detrimental effects of scientific specialism. PMID:24421049

  5. Methamphetamine abuse.

    PubMed

    Winslow, Bradford T; Voorhees, Kenton I; Pehl, Katherine A

    2007-10-15

    Methamphetamine is a stimulant commonly abused in many parts of the United States. Most methamphetamine users are white men 18 to 25 years of age, but the highest usage rates have been found in native Hawaiians, persons of more than one race, Native Americans, and men who have sex with men. Methamphetamine use produces a rapid, pleasurable rush followed by euphoria, heightened attention, and increased energy. Possible adverse effects include myocardial infarction, stroke, seizures, rhabdomyolysis, cardiomyopathy, psychosis, and death. Chronic methamphetamine use is associated with neurologic and psychiatric symptoms and changes in physical appearance. High-risk sexual activity and transmission of human immunodeficiency virus are also associated with methamphetamine use. Use of methamphetamine in women who are pregnant can cause placental abruption, intrauterine growth retardation, and preterm birth, and there can be adverse consequences in children exposed to the drug. Treatment of methamphetamine intoxication is primarily supportive. Treatment of methamphetamine abuse is behavioral; cognitive behavior therapy, contingency management, and the Matrix Model may be effective. Pharmacologic treatments are under investigation.

  6. Prescription Drug Abuse: From Epidemiology to Public Policy

    PubMed Central

    McHugh, R. Kathryn; Nielsen, Suzanne; Weiss, Roger D.

    2014-01-01

    Prescription drug abuse has reached an epidemic level in the United States. The prevalence of prescription drug abuse escalated rapidly beginning in the late 1990s, requiring a significant increase in research to better understand the nature and treatment of this problem. Since this time, a research literature has begun to develop and has provided important information about how prescription drug abuse is similar to, and different from the abuse of other substances. This introduction to a special issue of the Journal of Substance Abuse Treatment on prescription drug abuse provides an overview of the current status of the research literature in this area. The papers in this special issue include a sampling of the latest research on the epidemiology, clinical correlates, treatment, and public policy considerations of prescription drug abuse. Although much has been learned about prescription drug abuse in recent years, this research remains in early stages, particularly with respect to understanding effective treatments for this population. Future research priorities include studies on the interaction of prescription drugs with other licit and illicit substances, the impact of prescription drug abuse across the lifespan, the optimal treatment for prescription drug abuse and co-occurring conditions, and effective public policy initiatives for reducing prescription drug abuse. PMID:25239857

  7. Prescription drug abuse: from epidemiology to public policy.

    PubMed

    McHugh, R Kathryn; Nielsen, Suzanne; Weiss, Roger D

    2015-01-01

    Prescription drug abuse has reached an epidemic level in the United States. The prevalence of prescription drug abuse escalated rapidly beginning in the late 1990s, requiring a significant increase in research to better understand the nature and treatment of this problem. Since this time, a research literature has begun to develop and has provided important information about how prescription drug abuse is similar to, and different from the abuse of other substances. This introduction to a special issue of the Journal of Substance Abuse Treatment on prescription drug abuse provides an overview of the current status of the research literature in this area. The papers in this special issue include a sampling of the latest research on the epidemiology, clinical correlates, treatment, and public policy considerations of prescription drug abuse. Although much has been learned about prescription drug abuse in recent years, this research remains in early stages, particularly with respect to understanding effective treatments for this population. Future research priorities include studies on the interaction of prescription drugs with other licit and illicit substances, the impact of prescription drug abuse across the lifespan, the optimal treatment for prescription drug abuse and co-occurring conditions, and effective public policy initiatives for reducing prescription drug abuse.

  8. A Unique Program for Preschool Children of Substance Abusers.

    ERIC Educational Resources Information Center

    Howze, Kate; Howze, Wendell M.

    A pilot program was designed to address the special problems of children of substance abusers. The program was established at the Child Development and Family Guidance Center by Operation PAR, a nationally recognized substance abuse treatment and prevention program. The staff are well-trained preschool professionals who have received special…

  9. Medical advances in child sexual abuse.

    PubMed

    Alexander, Randell A

    2011-09-01

    This volume is the first of a two-part special issue detailing state of the art practice in medical issues around child sexual abuse. The six articles in this issue explore methods for medical history evaluation, the rationale for when sexual examinations should take place, specific hymenal findings that suggest a child has been sexually abused, the healing of genital injuries, approaches to interpretation of medical findings, and the neurological harm of sexual abuse. From the initial history to the process of the medical examination, the mechanics of what a genital examination might show, and the neurobiological consequences, it is demonstrated that the harm of sexual abuse is has more effect on the brain than the genital area.

  10. 75 FR 71711 - National Institute on Drug Abuse; Notice of Closed Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-24

    ... imposed by the review and funding cycle. Name of Committee: National Institute on Drug Abuse Special....: 93.279, Drug Abuse and Addiction Research Programs, National Institutes of Health, HHS) Dated... HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Notice of Closed...

  11. 77 FR 3481 - National Institute on Drug Abuse Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-01-24

    ... of Federal Domestic Assistance Program Nos.: 93.279, Drug Abuse and Addiction Research Programs... Institute on Drug Abuse Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory Committee... unwarranted invasion of personal privacy. Name of Committee: National Institute on Drug Abuse Special...

  12. How to Handle Abuse

    MedlinePlus

    ... What Is Happening en español Cómo manejar el abuso Grown-ups are usually there to help and ... to understand the different types of abuse: physical, sexual, verbal or emotional, and neglect. Physical abuse: Physical ...

  13. Students and Drug Abuse

    ERIC Educational Resources Information Center

    Todays Educ, 1969

    1969-01-01

    Introduction to "Students and Drug Abuse, prepared by the Public Information Branch and Center for Studies of Narcotic and Drug Abuse, National Institute of Mental Health, in cooperation with the staff of Today's Education.

  14. Alcoholism and Alcohol Abuse

    MedlinePlus

    ... their drinking causes distress and harm. It includes alcoholism and alcohol abuse. Alcoholism, or alcohol dependence, is a disease that causes ... groups. NIH: National Institute on Alcohol Abuse and Alcoholism

  15. Prescription Drug Abuse

    MedlinePlus

    ... from what the doctor prescribed, it is called prescription drug abuse. It could be Taking a medicine that was prescribed for someone else Taking a ... at higher doses or when taken with other medicines. NIH: National Institute on Drug Abuse

  16. Child abuse - physical

    MedlinePlus

    ... way Uses harsh discipline Was abused as a child Alcohol or drug problems Emotional problems or mental illness ... Physical abuse - children References Berkowitz CD, Stewart ST. Child maltreatment. In: Marx JA, Hockberger RS, Walls RM, eds. ...

  17. Foster or Adopted Children Who Have Been Sexually Abused

    MedlinePlus

    ... abused may demonstrate behaviors that are unusual, excessive, aggressive, or explicit. There is no one specific sign ... or exploited, and others may be angry and aggressive towards others. You may need to pay special ...

  18. Elder Abuse among African Americans

    ERIC Educational Resources Information Center

    Tauriac, Jesse J.; Scruggs, Natoschia

    2006-01-01

    Perceptions of extreme, moderate, and mild forms of elder abuse among African-American women (n=25) and men (n=10) were examined. African-American respondents emphasized physical abuse when giving examples of extremely abusive behavior. Along with physical abuse, verbal abuse was the most frequently identified form of abuse, and was significantly…

  19. Child Abuse: Educator's Responsibilities. Revised.

    ERIC Educational Resources Information Center

    California State Office of the Attorney General, Sacramento. Crime Prevention Center.

    This document presents the educator with a guide to child abuse. A section defining child abuse examines the issues of physical abuse, physical neglect, sexual abuse, and emotional maltreatment. Areas discussed for these types of abuse include abuse indicators, location of injury, history, behavioral indicators, and types of injury. Incestuous and…

  20. Nephrology in Latin America, with special emphasis on Brazil.

    PubMed

    Zatz, Roberto; Romão, J E; Noronha, I L

    2003-02-01

    Latin America constitutes a complex universe that shows extreme variation regarding socioeconomic and human development. Brazil is the largest and most populous Latin American country, and combines characteristics encountered in developed countries with problems typically associated with the poorest regions of the world. These disparities condition the profile of renal disease in Brazil, with glomerulonephritis still the leading cause of ESRD. Little is known about the epidemiology of renal disease in the Brazilian (or Latin American) native population, which is numerous in some Central and South American countries, but constitute a very small minority in Brazil. However, interesting information has been obtained from the Yanomamis, a tribe living in Northern Brazil and Southern Venezuela. Hypertension is virtually absent among these people, who ingest very little sodium, lending strong support to the concept that sodium retention, a "civilization" factor, plays a role in the pathogenesis of arterial hypertension. Despite Brazil's striking socioeconomic disparities, access to RRT is in principle accessible to all those in need of it. The dialysis units have been modernized in recent years, whereas the Government covers most expenses related to RRT. However, the prevalence of RRT in Brazil is currently approximately 320 per million population, less than one third as high as in the US, suggesting that ESRD may be underdiagnosed in the country. Much effort is still needed to limit the prevalence of renal disease and to improve the quality and the reach of RRT in Brazil and in Latin America.

  1. Morbillivirus infections, with special emphasis on morbilliviruses of carnivores.

    PubMed

    Barrett, T

    1999-09-01

    Morbilliviruses infections cause significant mortality in human beings and animals. Measles virus is responsible for up to two million childhood deaths annually in the developing world, while rinderpest and peste des petits ruminants cause severe epizootics in domestic and wild ruminants in areas of the world where they remain endemic. Canine distemper virus (CDV) is a cause of fatal disease in many species of carnivores. Distemper is controlled by vaccination in domestic dogs and farmed mink, but it may be impossible to eradicate the virus because of its global distribution and wide variety of susceptible host species, which includes both freshwater and marine seals. Research is currently under way to develop new recombinant vaccines, since the currently available live attenuated vaccines for CDV are not safe for use for all species and many valuable zoo animals need to be protected from CDV. New morbilliviruses with potentially disastrous ecological consequences for marine mammals have been discovered in the past decade; phocid distemper virus (PDV) in seals and the cetacean morbillivirus (CMV) has been found in dolphins, whales and porpoises. Reverse transcription, coupled with the polymerase chain reaction (RT/PCR) and nucleic acid sequencing, has been used to characterise the morbilliviruses and has given insights into the evolution of this virus genus.

  2. A purview of waste management evolution: Special emphasis on USA

    SciTech Connect

    Kollikkathara, Naushad Feng, Huan; Stern, Eric

    2009-02-15

    The generation of waste in urban regions over time is seen to impact the balance of anthropogenic and natural resources. Various national and international initiatives to manage urban solid waste are in place and has thus have evolved at present to form an assortment of different subcomponents involving environmental, administrative, regulatory, scientific, market, technology, and socio-economic factors, which has increasing bearing on the US due to its volume and nature of discards. This paper draws together the various aspects of municipal solid waste (MSW) management as it evolved, particularly in the American society through reviewing works and findings. In many parts of the country, waste management at present, primarily involves landfilling, incineration with and without energy recovery, recycling and composting. Legislation, nature of wastes and market trends continue to redefine management operations and its responsibilities and impacts. Complexities are added to it by the nature of urban development as well. New studies and concepts like 3Rs, cradle-to-cradle, industrial ecology, and integrated waste management are adding new dimensions for solving waste problems towards achieving sustainable resource use. Local initiatives, both public and private are in the forefront of adopting alternate waste management procedures. The assistance from various government and private bodies, supporting shifts in waste management approaches, have immense value, as according to the new paradigms, nothing goes to waste.

  3. Distributed data base systems with special emphasis toward POREL

    NASA Technical Reports Server (NTRS)

    Neuhold, E. J.

    1984-01-01

    In the last few years a number of research and advanced development projects have resulted in distributed data base management prototypes. POREL, developed at the University of Stuttgart, is a multiuser, distributed, relational system developed for wide and local area networks of minicomputers and advanced micros. The general objectives of such data base systems and the architecture of POREL are discussed. In addition a comparison of some of the the existing distributed DMBS is included to provide the reader with information about the current state of the art.

  4. Biodiesel production with special emphasis on lipase-catalyzed transesterification.

    PubMed

    Bisen, Prakash S; Sanodiya, Bhagwan S; Thakur, Gulab S; Baghel, Rakesh K; Prasad, G B K S

    2010-08-01

    The production of biodiesel by transesterification employing acid or base catalyst has been industrially accepted for its high conversion and reaction rates. Downstream processing costs and environmental problems associated with biodiesel production and byproducts recovery have led to the search for alternative production methods. Recently, enzymatic transesterification involving lipases has attracted attention for biodiesel production as it produces high purity product and enables easy separation from the byproduct, glycerol. The use of immobilized lipases and immobilized whole cells may lower the overall cost, while presenting less downstream processing problems, to biodiesel production. The present review gives an overview on biodiesel production technology and analyzes the factors/methods of enzymatic approach reported in the literature and also suggests suitable method on the basis of evidence for industrial production of biodiesel.

  5. A review of plague persistence with special emphasis on fleas.

    PubMed

    Wimsatt, Jeffrey; Biggins, Dean E

    2009-06-01

    Sylvatic plague is highly prevalent during infrequent epizootics that ravage the landscape of western North America. During these periods, plague dissemination is very efficient. Epizootics end when rodent and flea populations are decimated and vectored transmission declines. A second phase (enzootic plague) ensues when plague is difficult to detect from fleas, hosts or the environment, and presents less of a threat to public health. Recently, researchers have hypothesized that the bacterium (Yersinia pestis) responsible for plague maintains a continuous state of high virulence and thus only changes in transmission efficiency explain the shift between alternating enzootic and epizootic phases. However, if virulent transmission becomes too inefficient, strong selection might favor an alternate survival strategy. Another plausible non-exclusive hypothesis, best supported from Asian field studies, is that Y. pestis persists (locally) at foci by maintaining a more benign relationship within adapted rodents during the long expanses of time between outbreaks. From this vantage, it can revert to the epizootic (transmission efficient) form. Similarly, in the United States (US), enzootic plague persistence has been proposed to develop sequestered within New World rodent carriers. However, the absence of clear support for rodent carriers in North America has encouraged a broader search for alternative explanations. A telluric plague existence has been proposed. However, the availability of flea life stages and their hosts could critically supplement environmental plague sources, or fleas might directly represent a lowlevel plague reservoir. Here, we note a potentially pivotal role for fleas. These epizootic plague vectors should be closely studied with newer more exacting methods to determine their potential to serve as participants in or accomplices to a plague persistence reservoir.

  6. Environmental Quality and Occupational Health Special Emphasis Area Plan (SEAP)

    DTIC Science & Technology

    1989-06-01

    applications. 5 (2) Related Program: PE/Proj Title 62202F Aerospace Biotechnology Proj 6302 Operational and Environmental Toxic Hazards in Ai "orce...a material eirl" in the acquisition process. (2) Related Program: PE/Proj Title 62202F Aerospace Biotechnology Proj 6302 Operationcl and Environmental...by USAF laboratories, resulting in substantial cost and time savings. 6 (2) Related Program: PE/Proj Title 62202F Aerospace Biotechnology Proj 6302

  7. Synthetic fuels for ground transportation with special emphasis on hydrogen

    NASA Technical Reports Server (NTRS)

    Singh, J. J.

    1975-01-01

    The role of various synthetic fuels, for ground transportation in the United States, was examined for the near term (by 1985) and the longer term applications (1985-2000 and beyond 2000). Feasible options include synthetic oil, methanol, electric propulsion, and hydrogen. It is concluded that (1) the competition during the next 50 years will be for the fuels of all types, rather than among the fuels; (2) extensive domestic oil and gas exploration should be initiated concurrent with the development of several alternate fuels and related ancillaries; and (3) hydrogen, as an automotive fuel, seems to be equivalent to gasoline for optimum fuel to air mixtures. As a pollution free, high energy density fuel, hydrogen deserves consideration as the logical replacement for the hydrocarbons. Several research and development requirements, essential for the implementation of hydrogen economy for ground transportation, were identified. Extensive engineering development and testing activities should be initiated to establish hydrogen as the future automotive fuel, followed by demonstration projects and concerted efforts at public education.

  8. A review of plague persistence with special emphasis on fleas

    USGS Publications Warehouse

    Wimsatt, Jeffrey; Biggins, Dean E.

    2009-01-01

    Here, we note a potentially pivotal role for fleas. These epizootic plague vectors should be closely studied with newer more exacting methods to determine their potential to serve as participants in or accomplices to a plague persistence reservoir.

  9. Polychlorinated Biphenyl (PCB) carcinogenicity with special emphasis on airborne PCBs

    PubMed Central

    Robertson, Larry W.; Ludewig, Gabriele

    2011-01-01

    Polychlorinated biphenyls (PCBs) are industrial chemicals used in various applications requiring chemical stabilityand have now become widely dispersed. Their characteristics of persistence, low water/higher lipid solubility, contribute to their ability to bioconcentrate and bioaccumulate. Traditionally PCBs have been regulated as food contaminants and the general population is primarily exposed by that route. PCBs in foodstuffs are generally higher chlorinated, resistant to metabolic breakdown, and elicit toxic changes that are thought to be predominantly receptor/parent PCB-driven. But for certain occupational exposures, and for those persons residing or working in contaminated buildings, and in large cities, an inhalation route of exposure may predominate. Airborne PCBs are, in contrast to foodborne PCBs, lower chlorinated, more volatile, and subject to metabolic attack. In this review, we have explored (geno-) toxic manifestations of PCBs typical of those found in air. Here metabolic conversion of the parent PCB to hydroxylated and other metabolic progeny appear to play a dominant role, especially in genotoxicity. We should be cognizant of the impact of exposures to airborne PCBs for those individuals who are occupationally exposed, for persons living near contaminated sites, for those who work or go to school in contaminated buildings, and especially cognizant of the young, the socio-economically disadvantaged and medically-underserved or nutritionally-deficient populations. PMID:21686028

  10. Brazilian borreliosis with special emphasis on humans and horses.

    PubMed

    Basile, Roberta Carvalho; Yoshinari, Natalino Hajime; Mantovani, Elenice; Bonoldi, Virgínia Nazário; Macoris, Delphim da Graça; Queiroz-Neto, Antonio de

    Borreliosis caused by Borrelia burgdorferi sensu lato is a cosmopolitan zoonosis studied worldwide; it is called Lyme disease in many countries of the Northern Hemisphere and Lyme-like or Baggio-Yoshinari Syndrome in Brazil. However, despite the increasing number of suspect cases, this disease is still neglected in Brazil by the medical and veterinary communities. Brazilian Lyme-like borreliosis likely involves capybaras as reservoirs and Amblyomma and Rhipicephalus ticks as vectors. Thus, domestic animals can serve as key carriers in pathogen dissemination. This zoonosis has been little studied in horses in Brazil. The first survey was performed in the state of Rio de Janeiro, and this Brazilian Borreliosis exhibits many differences from the disease widely described in the Northern Hemisphere. The etiological agent shows different morphological and genetic characteristics, the disease has a higher recurrence rate after treatment with antibiotics, and the pathogen stimulates intense symptoms such as a broader immune response in humans. Additionally, the Brazilian zoonosis is not transmitted by the Ixodes ricinus complex. With respect to clinical manifestations, Baggio-Yoshinari Syndrome has been reported to cause neurological, cardiac, ophthalmic, muscle, and joint alterations in humans. These symptoms can possibly occur in horses. Here, we present a current panel of studies involving the disease in humans and equines, particularly in Brazil.

  11. Welfare Reform and Substance Abuse

    PubMed Central

    Metsch, Lisa R; Pollack, Harold A

    2005-01-01

    The 1996 Personal Responsibility and Work Opportunity Reconciliation Act (PRWORA) changed the nature, purpose, and financing of public aid. Researchers, administrators, and policymakers expressed special concern about the act's impact on low-income mothers with substance use disorders. Before PRWORA's passage, however, little was known about the true prevalence of these disorders among welfare recipients or about the likely effectiveness of substance abuse treatment interventions for welfare recipients. Subsequent research documented that substance abuse disorders are less widespread among welfare recipients than was originally thought and are less common than other serious barriers to self-sufficiency. This research also showed significant administrative barriers to the screening, assessment, and referral of drug-dependent welfare recipients. This article summarizes current research findings and examines implications for welfare reform reauthorization. PMID:15787954

  12. A child sexual abuse research project: a brief endnote.

    PubMed

    Roberts, Susan; Vanstone, Maurice

    2014-01-01

    There is a dearth of research on sexual abuse perpetrated by educators. Although the problem is receiving increasing attention, little emphasis has been placed on abuse directed at younger schoolchildren and on offenders' accounts of this form of abuse. Here, we attempt to address this gap in knowledge by exploring the narratives of five convicted, imprisoned male child sexual abusers, each of whom worked with children in educational settings in the United Kingdom. We draw on four themes that emerged from detailed interviews with offenders, namely: the power of reputation, authority and control, the "front of invulnerability," and disclosure of abuse. We conclude by considering the implications of our work for policy and practice.

  13. Elder Abuse Awareness Project.

    ERIC Educational Resources Information Center

    Doyle, Kathleen; Morrow, Marilyn J.

    1985-01-01

    The Elder Abuse Awareness Project was undertaken: (1) to determine the incidence of abuse and neglect in seven Illinois counties; and (2) to develop, produce, and distribute educational materials on elder abuse for the service provider and for senior citizens. Results are presented and discussed. (MT)

  14. Elder Abuse in Japan

    ERIC Educational Resources Information Center

    Arai, Mizuho

    2006-01-01

    Perceptions of elder abuse were examined in Japanese women (n =100) and men (n =46). Japanese women and men both emphasized physical aggression, followed by neglect and blaming, when giving examples of extremely abusive behavior. Physical aggression was also the most frequently mentioned type of moderate elder abuse, followed by neglect, economic…

  15. Elder Abuse Awareness Project.

    ERIC Educational Resources Information Center

    Morrow, Marilyn J.; Doyle, Kathleen

    The Elder Abuse Awareness Project was developed to determine the incidence of abuse and neglect of elderly people in several rural counties in central Illinois. A primary purpose of the study was to survey service providers as to their actual encounters with elder abuse and neglect. Each provider was asked about warning signs or cues that were…

  16. Substance Abuse. Policy Statement.

    ERIC Educational Resources Information Center

    National Collaboration for Youth, Washington, DC.

    This paper presents the policy statement on substance abuse from the National Collaboration for Youth (NCY). The policy statement section lists programs and activities supported by the NCY. A section on background includes a statement of the issue of substance abuse. Areas examined in this section include alcohol abuse and drunk driving among…

  17. Developments in special geometry

    NASA Astrophysics Data System (ADS)

    Mohaupt, Thomas; Vaughan, Owen

    2012-02-01

    We review the special geometry of Script N = 2 supersymmetric vector and hypermultiplets with emphasis on recent developments and applications. A new formulation of the local c-map based on the Hesse potential and special real coordinates is presented. Other recent developments include the Euclidean version of special geometry, and generalizations of special geometry to non-supersymmetric theories. As applications we disucss the proof that the local r-map and c-map preserve geodesic completeness, and the construction of four- and five-dimensional static solutions through dimensional reduction over time. The shared features of the real, complex and quaternionic version of special geometry are stressed throughout.

  18. Increasing Knowledge of Sexual Abuse: A Study with Elementary School Children in Hawai'i

    ERIC Educational Resources Information Center

    Baker, Charlene K.; Gleason, Kristen; Naai, Rachel; Mitchell, Jennifer; Trecker, Christine

    2013-01-01

    Objective: Child sexual abuse is a significant health problem with potential long-term consequences for victims. Therefore, prevention and education programs are critical. This preliminary study evaluates changes in children’s knowledge of sexual abuse using a school-based train-the-trainer curriculum. Emphasis was placed on developing a…

  19. Psychiatric Disabilities and Substance Abuse Disorder: Psychosocial and Vocational Concerns--Implications for Rehabilitation Professionals

    ERIC Educational Resources Information Center

    Patterson, Latofia; Templeton, Mary Anne

    2006-01-01

    The purpose of this article is to review the literature on the comorbidity of substance abuse and psychiatric disorder. The paper examines the medical, psychosocial, and vocational rehabilitation concerns associated with substance abuse and psychiatric disorder comorbidity. A greater emphasis is placed on vocational concerns and the role of…

  20. American Indian and Alaska Native Substance Abuse: Co-Morbidity and Cultural Issues

    ERIC Educational Resources Information Center

    Gray, Norma; Nye, Patricia S.

    2001-01-01

    The devastating impact of substance abuse on American Indians and Alaska Natives (AI/ANs) is reviewed with an emphasis on psychological and physical effects. Co-morbidity of substance abuse, trans-generational trauma, Post-Traumatic Stress Disorder, and depression among AI/ANs is also discussed since each condition may cause, impact, and/or…

  1. Inhalant Abuse and Dextromethorphan.

    PubMed

    Storck, Michael; Black, Laura; Liddell, Morgan

    2016-07-01

    Inhalant abuse is the intentional inhalation of a volatile substance for the purpose of achieving an altered mental state. As an important, yet underrecognized form of substance abuse, inhalant abuse crosses all demographic, ethnic, and socioeconomic boundaries, causing significant morbidity and mortality in school-aged and older children. This review presents current perspectives on epidemiology, detection, and clinical challenges of inhalant abuse and offers advice regarding the medical and mental health providers' roles in the prevention and management of this substance abuse problem. Also discussed is the misuse of a specific "over-the-counter" dissociative, dextromethorphan.

  2. Identifying the sexually abused deaf child: the otolaryngologist's role.

    PubMed

    Brookhouser, P E; Sullivan, P; Scanlan, J M; Garbarino, J

    1986-02-01

    As a primary physician for most deaf children, the otolaryngologist must be able to identify signs and symptoms of sexual abuse. Child sexual abuse is a topic of national concern as epidemiologic data indicate more than 100,000 American children become victims annually. This paper provides an overview of the incidence, demographic characteristics, risk factors, and dynamics of child sexual abuse within both the general handicapped and, specifically, the hearing imparied populations. Strategies for identifying the sexually abused hearing impaired child are delineated including the physical appearance and behavioral manifestations of child victims, as well as the characteristics of abusive caretakers and perpetrators. Case summaries are presented which illustrate these characteristics. A national center specializing in the evaluation and treatment of abused handicapped children is described.

  3. Youth Drug Abuse in New York. Hearing before the Subcommitte of the Committee on Appropriations. United States Senate, Ninety-Eighth Congress, First Session. Special Hearing: Congressional Witnesses, Nondepartmental Witnesses.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Committee on Appropriations.

    This document contains Congressional and nondepartmental witness testimony from the Congressional hearing on youth drug abuse in New York. Opening statements are presented on the incidence of drug use in America, the role of the federal government, the impact of drugs on youth, foreign country production of illegal drugs, funding to fight illegal…

  4. Speaking about the unspeakable: sexually abused men striving toward language.

    PubMed

    Andersen, Torbjørn Herlof

    2008-03-01

    Traditionally, sexual abuse of males has not been an issue of priority among politicians or researchers. When addressed, focus is often on context or harmful effects of the abuse. This article is based on the idea of reality as socially constructed, examining possible ways for sexually abused males to come to terms with their experiences. The emphasis is on accessible discursive resources on "the abused male" and how cultural stereotypes of manliness influence and limit individual and societal constructions. An important key to reconstruction of abuse history and selfhood lies in acceptance of the idea of men as suppressed. Sexually abused males tend to feel marginalized and different. However, when given the opportunity, they offer alternative discourses of manliness with the potential for bringing sexually abused males out of the shadows, assisting them in better understanding, dealing with, and explaining their experiences to themselves and others. This article brings out the importance of a gender-sensitive approach to working politically as well as directly with men who have been sexually abused. The horizon of understanding in professional social work needs to include attention to stereotypical constructions of manliness that reject men's experiences of being "victims."

  5. Skin manifestations of child abuse.

    PubMed

    Ermertcan, Aylin Turel; Ertan, Pelin

    2010-01-01

    Child abuse is a major public health problem all over the world. There are four major types of abuse: physical abuse, sexual abuse, emotional abuse and neglect. The most common manifestations of child abuse are cutaneous and their recognition; and differential diagnosis is of great importance. Clinicians, especially dermatologists, should be alert about the skin lesions of child abuse. In the diagnosis and management of child abuse, a multidisciplinary approach with ethical and legal procedures is necessary. In this manuscript, cutaneous manifestations of physical, sexual, emotional abuse and neglect are reviewed and discussed.

  6. Note from Iran: Self-reported elder abuse in Qazvin, 2012.

    PubMed

    Oveisi, Sonia; Karimi, Rana; Mahram, Manoochehr

    2014-01-01

    This brief report provides a first look at self-reported instances of elder abuse by a sample of people 60 years and older living in Qazvin, Iran. Six hundred community-dwelling persons, drawn from the registry files of each health center in Qazin, completed questionnaires during April to October 2012. At least 80% of the participants reported experiencing some form of psychological abuse, financial abuse, and/or neglect at least once during a 2-month period. Physical and sexual abuse were rarely reported. Despite a strong Iranian cultural emphasis on respect for elders, the self-reporting of elder abuse, especially psychological abuse, is greater than our expectation. We recommend that health-related policies and programs begin to identify elder abuse and neglect as a first step in prevention.

  7. Alcohol and the Physically Impaired: Special Focus.

    ERIC Educational Resources Information Center

    Boros, Alexander, Ed.

    1989-01-01

    The articles in this special issue explore the connections between the dual disabilities of alcohol abuse and physical impairment, and reflect progress made in exploring the causes and treatments of alcohol abuse among the physically impaired. Selected articles include: "Results of a Model Intervention Program for Physically Impaired…

  8. Overcoming Obstacles to Drug Abuse Research with Families.

    ERIC Educational Resources Information Center

    Glynn, Thomas J.

    Although there has been a significant amount of research on the families of drug abusers, this field has encountered a number of obstacles to its continued growth. Some of these problems include an emphasis of research on opiate use, methodological hindrances, and lack of a constituency. A review of two concurrent national processes, the White…

  9. City Views on Drug Abuse: A Washington, DC Survey.

    ERIC Educational Resources Information Center

    Hart (Peter D.) Research Associates, Inc., Washington, DC.

    A telephone survey was done of a representative sample of 801 adults in the District of Columbia. The survey explored District residents' attitudes about the current situation in the city and in their neighborhoods, with specific emphasis on their attitudes toward drug abuse and drug policy in the District of Columbia. The margin of error for the…

  10. Child Abuse Amendments of 1983.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. House Committee on Education and Labor.

    The booklet presents the report of the U.S. House of Representatives Committee on Education and Labor regarding the 1983 Child Abuse Amendments to the Child Abuse Prevention and Treatment Act and the Child Abuse Prevention and Treatment and Adoption Reform Act of 1978. The Amendment expands the definition of child abuse to include abuse by…

  11. 62 FR 999 - Sepcial Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    1997-01-07

    ... Sepcial Emphasis Panel in Information, Robotics and Intelligent Systems; Notice of Meeting In accordance... announces the following meeting. Name: Special Emphasis Panel in Information, Robotics and Intelligent (1200... NSF for financial support. Agenda: To review and evaluate Robotics and Machine and...

  12. Elder abuse and neglect.

    PubMed

    Muehlbauer, Melissa; Crane, Patricia A

    2006-11-01

    Elder abuse and neglect is a critical health care issue that must be brought to the attention of health care providers and older adults' family members. Adults older than 65 who live at home or in long-term care facilities may be at risk for abuse. Nurses should be aware of the causes, screening questions, symptoms of abuse, and resources in the community. Armed with information and a better understanding about the issue, nurses can minimize the devastating effects of abuse on older adults and their families.

  13. Alternative drugs of abuse.

    PubMed

    Sutter, M E; Chenoweth, J; Albertson, T E

    2014-02-01

    The incidence of drug abuse with alternative agents is increasing. The term "alternative drugs of abuse" is a catch-all term for abused chemicals that do not fit into one of the classic categories of drugs of abuse. The most common age group abusing these agents range from 17 to 25 years old and are often associated with group settings. Due to their diverse pharmacological nature, legislative efforts to classify these chemicals as a schedule I drug have lagged behind the development of new alternative agents. The potential reason for abuse of these agents is their hallucinogenic, dissociative, stimulant, anti-muscarinic, or sedative properties. Some of these drugs are easily obtainable such as Datura stramonium (Jimson Weed) or Lophophora williamsii (Peyote) because they are natural plants indigenous to certain regions. The diverse pharmacology and clinical effects of these agents are so broad that they do not produce a universal constellation of signs and symptoms. Detailed physical exams are essential for identifying clues leading one to suspect an alternative drug of abuse. Testing for the presence of these agents is often limited, and even when available, the results do not return in a timely fashion. Intoxications from these agents pose unique challenges for health care providers. Physician knowledge of the physiological effects of these alternative agents and the local patterns of drug of abuse are important for the accurate diagnosis and optimal care of poisoned patients. This review summarizes the current knowledge of alternative drugs of abuse and highlights their clinical presentations.

  14. State Pilots Sweeping Changes in Special Ed

    ERIC Educational Resources Information Center

    Adkins, Gary

    2007-01-01

    The Illinois State Board of Education launched a special education pilot project using a concept called Response to Intervention (RtI) that some experts believe could lead to a sea change in the way special education is provided. RtI places greater emphasis on early intervention and a reduced emphasis on psychological testing and other traditional…

  15. Cutaneous manifestations of child abuse.

    PubMed

    Kos, Liborka; Shwayder, Tor

    2006-01-01

    Dermatologists and child abuse are not frequently associated in the minds of most physicians. Yet the most common manifestations of child abuse are cutaneous. This article reviews cutaneous manifestations of physical abuse, including bruises, lacerations, abrasions, human bites, and burns. It also discusses ways that dermatologists can differentiate abusive injuries from accidental ones as well as from the many dermatologic conditions that can mimic child abuse. Finally, we review what actions the dermatologist should take when suspecting abuse in a patient.

  16. Expert systems in treating substance abuse.

    PubMed

    Wesson, D R; Hink, R H

    1990-05-01

    Computer programs can assist humans in solving complex problems that cannot be solved by traditional computational techniques using mathematic formulas. These programs, or "expert systems," are commonly used in finance, engineering, and computer design. Although not routinely used in medicine at present, medical expert systems have been developed to assist physicians in solving many kinds of medical problems that traditionally require consultation from a physician specialist. No expert systems are available specifically for drug abuse treatment, but at least one is under development. Where access to a physician specialist in substance abuse is not available for consultation, this expert system will extend specialized substance abuse treatment expertise to nonspecialists. Medical expert systems are a developing technologic tool that can assist physicians in practicing better medicine.

  17. Etiology of Drug Abuse: A Narrative Analysis

    PubMed Central

    Jadidi, Nadjme

    2014-01-01

    Introduction and Aim. Further gains in the prevention of drug abuse disorders require in-depth and holistic understanding of the risk factors of addiction from different perspectives. Lay persons and experts have different concepts of risk which could complement each other. The purpose of this study was to elaborate drug abuse risk factors through the story of individuals who had become drug dependent. Design and Methods. In this qualitative research, 33 individuals attending treatment centres for drug abuse were interviewed about the story of their addiction in Kerman, Iran. Interview questions were around the story of the participants. Results. All participants were male and in the age range of 18–40 years. Narrative analysis identified five themes as the main risk factors: family factors, peer pressure, the effect of gateway drugs (especially waterpipe), individual characteristics, and the community factors. More emphasis was placed upon the role of family factors, peer influence, and gateway effect. Discussion and Conclusion. This study elicited information from drug dependent subjects regarding the risk factors of drug abuse. According to drug dependent individuals' views, more attention should be devoted to family and peer influences by policy makers, in developing culture-based preventive strategies. PMID:25247105

  18. Forensic, Cultural, and Systems Issues in Child Sexual Abuse Cases--Part 2: Research and Practitioner Issues

    ERIC Educational Resources Information Center

    Tishelman, Amy C.; Geffner, Robert

    2010-01-01

    This article introduces the second issue of the special double issue focusing on forensic, cultural, and systems issues in child sexual abuse cases. We briefly review the articles, which include a discussion of child sexual abuse myths, an empirical analysis of extended child sexual abuse evaluations, an article on the role of the medical provider…

  19. 78 FR 2676 - Draft Guidance for Industry on Abuse-Deterrent Opioids-Evaluation and Labeling; Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-14

    ...-deterrent properties of opioid analgesic products should be studied and evaluated, and what claims regarding....'' Prescription opioid analgesics are an important component of modern pain management, but abuse and misuse of... abuse and misuse is the development of opioid analgesics specially formulated to deter abuse....

  20. Substance Abuse Policy

    ERIC Educational Resources Information Center

    Cuzzolino, Robert

    This brochure outlines the substance abuse policy for students at the Philadelphia College of Osteopathic Medicine (PCOM/Pennsylvania). Noted are the dangers of substance abuse during the stressful time of medical training and later for the doctor and clients during professional practice. The policy's five goals are briefly stated. Described next…

  1. Alcoholism and Elder Abuse.

    ERIC Educational Resources Information Center

    Anetzberger, Georgia J.; And Others

    1994-01-01

    A comparison group study of abusing and nonabusing caregivers suggested a correlation between alcohol use and violence against elderly parents. Findings reveal that abusers were more likely than nonabusers to drink, to become intoxicated, and to be identified as having a drinking problem. Policy and practice implications are discussed. (Author)

  2. Adolescent Substance Abuse.

    ERIC Educational Resources Information Center

    Thorne, Craig R.; DeBlassie, Richard R.

    1985-01-01

    Cummings (1979), citing evidence from the National Institute of Drug Abuse, reports that one of every eleven adult Americans suffers from a severe addictive problem. Drug addiction is epidemic among teenagers; one of every six teenagers suffers from a severe addictive problem. This paper focuses on adolescent drug/substance abuse. (Author)

  3. Antitussives and substance abuse

    PubMed Central

    Burns, Jarrett M; Boyer, Edward W

    2013-01-01

    Abuse of antitussive preparations is a continuing problem in the United States and throughout the world. Illicit, exploratory, or recreational use of dextromethorphan and codeine/promethazine cough syrups is widely described. This review describes the pharmacology, clinical effects, and management of toxicity from commonly abused antitussive formulations. PMID:24648790

  4. Treating substance abuse: partner and family approaches.

    PubMed

    Klostermann, Keith; O'Farrell, Timothy J

    2013-01-01

    Historically, alcohol and other substance use disorders were viewed as individual-based problems that were most effectively treated by focusing on the diagnosed individual. However, in response to numerous clinical trials demonstrating the efficacy (and often superiority) of couple and family treatments for alcoholism and drug abuse, this emphasis on treating the individual has slowly given way to a greater awareness of family members' crucial roles in the etiology, maintenance, and long-term course of substance use and addictive behavior. As a result, clinicians are increasingly interested in understanding substance misuse from a systemic perspective and exploring how partner- and family-involved interventions may be used to address individuals' substance abuse.

  5. Prevention of substance abuse: a brief overview

    PubMed Central

    MEDINA-MORA, MARÍA ELENA

    2005-01-01

    Recent advances in psychosocial research and neurosciences have provided new avenues for prevention of substance abuse at the individual and community level. A series of risk and protective factors affecting the likelihood of using and abusing substances have been identified. The scope of prevention has been broadened, allowing the prescription of different interventions for individuals according to their varying degrees of vulnerability to substance experimentation, continuous use and dependence. An increased awareness of comorbidity between mental and substance use disorders provides an arena for prevention within psychiatry and related disciplines. Emphasis on program evaluation has helped identify cost effective programs and policies. The integration of prevention within healthy life style policies and programs, including interventions at the school, family and community levels, is more likely to produce the desired outcomes. PMID:16633497

  6. Abuse of prescription drugs.

    PubMed Central

    Wilford, B B

    1990-01-01

    An estimated 3% of the United States population deliberately misuse or abuse psychoactive medications, with severe consequences. According to the National Institute on Drug Abuse, more than half of patients who sought treatment or died of drug-related medical problems in 1989 were abusing prescription drugs. Physicians who contribute to this problem have been described by the American Medical Association as dishonest--willfully misprescribing for purposes of abuse, usually for profit; disabled by personal problems with drugs or alcohol; dated in their knowledge of current pharmacology or therapeutics; or deceived by various patient-initiated fraudulent approaches. Even physicians who do not meet any of these descriptions must guard against contributing to prescription drug abuse through injudicious prescribing, inadequate safeguarding of prescription forms or drug supplies, or acquiescing to the demands or ruses used to obtain drugs for other than medical purposes. PMID:2349801

  7. Parent abuse: a review.

    PubMed

    Kennair, Nicola; Mellor, David

    2007-10-01

    A recent focus of research and clinical practice has been on the issue of abuse of parents by their children (parent abuse). This paper reviews the literature on this phenomenon. While parent abuse falls under the umbrella of family violence, it appears to be qualitatively different from other forms of intra-family abuse. Research has primarily focused on prevalence rates and the characteristics of perpetrators and victims. While various factors such as gender, age, emotional attachment to parents, race/ethnicity, socioeconomic status, family stress and parenting style and structure have been associated with parent abuse, findings are equivocal. Etiological models are general and untested, and treatment approaches lack empirical support. It is concluded that more rigorous and extensive research is required in order to provide a deeper understanding of this complex issue, and to inform treatment approaches.

  8. Dextromethorphan Abuse in Adolescence

    PubMed Central

    Bryner, Jodi K.; Wang, Uerica K.; Hui, Jenny W.; Bedodo, Merilin; MacDougall, Conan; Anderson, Ilene B.

    2008-01-01

    Objectives To analyze the trend of dextromethorphan abuse in California and to compare these findings with national trends. Design A 6-year retrospective review. Setting California Poison Control System (CPCS), American Association of Poison Control Centers (AAPCC), and Drug Abuse Warning Network (DAWN) databases from January 1, 1999, to December 31, 2004. Participants All dextromethorphan abuse cases reported to the CPCS, AAPCC, and DAWN. The main exposures of dextromethorphan abuse cases included date of exposure, age, acute vs long-term use, coingestants, product formulation, and clinical outcome. Main Outcome Measure The annual proportion of dextromethorphan abuse cases among all exposures reported to the CPCS, AAPCC, and DAWN databases. Results A total of 1382 CPCS cases were included in the study. A 10-fold increase in CPCS dextromethorphan abuse cases from 1999 (0.23 cases per 1000 calls) to 2004 (2.15 cases per 1000 calls) (odds ratio, 1.48; 95% confidence interval, 1.43–1.54) was identified. Of all CPCS dextromethorphan abuse cases, 74.5% were aged 9 to 17 years; the frequency of cases among this age group increased more than 15-fold during the study (from 0.11 to 1.68 cases per 1000 calls). Similar trends were seen in the AAPCC and DAWN databases. The highest frequency of dextromethorphan abuse occurred among adolescents aged 15 and 16 years. The most commonly abused product was Coricidin HBP Cough & Cold Tablets. Conclusions Our study revealed an increasing trend of dextromethorphan abuse cases reported to the CPCS that is paralleled nationally as reported to the AAPCC and DAWN. This increase was most evident in the adolescent population. PMID:17146018

  9. Methylphenidate and dextroamphetamine abuse in substance-abusing adolescents.

    PubMed

    Williams, Robert J; Goodale, Leslie A; Shay-Fiddler, Michele A; Gloster, Susan P; Chang, Samuel Y

    2004-01-01

    The prevalence of methylphenidate and dextroamphetamine misuse and abuse was examined in 450 adolescents referred for substance abuse treatment. Twenty three percent reported nonmedical use of these substances and six percent were diagnosed as methylphenidate or dextroamphetamine abusers. Abuse was more common in individuals who were out of school and had an eating disorder. Methylphenidate and dextroamphetamine abuse appears to be much less common than abuse of most other substances. It does occur, however, and parents and schools need to exert greater control over the dispensing of these medications. Physicians are advised to prescribe non-stimulant medications (eg, bupropion) when treating attention deficit hyperactivity disorder in substance-abusing individuals.

  10. Encountering Child Abuse at Camp.

    ERIC Educational Resources Information Center

    Durall, John K.

    1997-01-01

    Defines child abuse, including the three categories: physical, sexual, and psychological. Presents characteristics and behaviors of each type of abuse, and long-term effects. Discusses how to handle abuse that occurs at camp, and the effects on the camp. Sidebars present abuse statistics, 15 activities that promote psychological wellness, and 8…

  11. Child Abuse and Mandated Reporting

    ERIC Educational Resources Information Center

    Woika, Shirley; Bowersox, Carissa

    2013-01-01

    Teachers and teachers-in-training are mandated reporters; they are legally required to report any suspected child abuse or neglect. This article describes: (1) How to file a report; (2) How prevalent child abuse is; (3) What abuse is; (4) What it means to be a mandated reporter; (5) When the report should be made; and (6) What to do if abuse is…

  12. Neurologic aspects of drug abuse.

    PubMed

    Goforth, Harold W; Murtaugh, Reed; Fernandez, Francisco

    2010-02-01

    Neurologic aspects of drug abuse vary. This article explains the general nature of drug abuse, identifies the physiologic effects of certain drugs, and briefly describes the neurobiology of addiction. This article also reviews available treatment options for those addicted to substances of abuse, and clarifies common misconceptions, including the differences between tolerance, abuse, and addiction.

  13. Uses and Abuses of Early Identification Programs.

    ERIC Educational Resources Information Center

    Zeitlin, Shirley

    Discussed is early identification of children having special educational or developmental needs, with emphasis on the use of screening to identify the potential high risk learner. Terms are defined and criteria to help select a screening instrument are given. The Zeitlin Early Identification Screening (ZEIS) is described as an example of a…

  14. Children intoxications: what is abuse and what is not abuse.

    PubMed

    Dinis-Oliveira, Ricardo Jorge; Magalhães, Teresa

    2013-04-01

    The curiosity and the natural tendency to explore the environment put young children at an increased risk of poisoning over older children and adults. Poisonings are a significant area of concern from 1 year of age and progressively contribute more to overall rates of morbidity and mortality until children reach adulthood. Particularly, the abuse of children by poisoning is also highly common with thousands of fatalities. A practical strategy is presented that aims to alert health, forensic, and law enforcement professionals to this problem and to demystify the preconception that it is a rare form of abuse or neglect. Compounds that are foreign to a living organism (xenobiotics) and those present within body (endobiotics), mainly involved in children intoxications and contextual examples related to exposure are also reviewed. Particular concern is given to concepts in the field of children poisoning. The described history and the clinical and toxicological evaluation are discussed, and harmonized protocols regarding correct procedures for sample collection to forensic toxicological analysis are proposed. Since children are particularly vulnerable to the toxic effects of high doses of xenobiotics and endobiotics, special consideration on the preparation of the environment that surrounds children in order minimize all possible risks will be also considered.

  15. Commentary: Indigenous Health Special Issue

    ERIC Educational Resources Information Center

    Tonmyr, Lil; Blackstock, Cindy

    2010-01-01

    This commentary highlights indigenous public health research from a special issue of the International Journal of Mental Health and Addiction dealing with child maltreatment, mental health, substance abuse and gambling. We focus on the emerging and growing research movement in Indigenous research through three important themes: 1) worldview and…

  16. Child Sexual Abuse

    MedlinePlus

    ... Z) Hepatitis HIV Mental Health Mental Health Home Suicide Prevention Substance Abuse Military Sexual Trauma PTSD Research ( ... include: PTSD and anxiety. Depression and thoughts of suicide. Sexual anxiety and disorders, including having too many ...

  17. Sexual Abuse of Children.

    ERIC Educational Resources Information Center

    Csapo, Marg

    1988-01-01

    Canadian reports and legislation are reviewed to highlight the school's role in prevention and reporting of suspicions of child sexual abuse. The vulnerability of handicapped children and child pornography are two areas of victimization emphasized. (Author/DB)

  18. Cough & Cold Medicine Abuse

    MedlinePlus

    ... Loss Surgery? A Week of Healthy Breakfasts Shyness Cough & Cold Medicine Abuse KidsHealth > For Teens > Cough & Cold ... Someone Quit? Avoiding DXM Why Do People Use Cough and Cold Medicines to Get High? There's an ...

  19. Opioid Abuse and Addiction

    MedlinePlus

    ... oxycodone, hydrocodone, fentanyl, and tramadol. The illegal drug heroin is also an opioid. Some opioids are made ... NAS). Opioid abuse may sometimes also lead to heroin use, because some people switch from prescription opioids ...

  20. Synthetic cathinone abuse

    PubMed Central

    Capriola, Michael

    2013-01-01

    The abuse of synthetic cathinones, widely known as bath salts, has been increasing since the mid-2000s. These substances are derivatives of the naturally occurring compound cathinone, which is the primary psychoactive component of khat. The toxicity of synthetic cathinones includes significant sympathomimetic effects, as well as psychosis, agitation, aggression, and sometimes violent and bizarre behavior. Mephedrone and methylenedioxypyrovalerone are currently the predominantly abused synthetic cathinones. PMID:23869180

  1. [Skin signs in child abuse].

    PubMed

    Pau-Charles, I; Darwich-Soliva, E; Grimalt, R

    2012-03-01

    Child abuse is far more prevalent today than is generally recognized. Up to 90% of victims suffer physical abuse that can be observed in signs on the skin. Dermatologists are particularly qualified to identify these signs and distinguish them from other conditions that can mimic abuse. This review covers the signs of child abuse that can be observed on the skin. We discuss clues that can help differentiate between lesions caused by abuse and those that are accidental, and we describe the skin conditions that mimic physical abuse.

  2. National Clearinghouse for Drug Abuse Information Report Series, Series 13, No. 1.

    ERIC Educational Resources Information Center

    National Inst. on Drug Abuse (DHEW/PHS), Rockville, MD. National Clearinghouse for Drug Abuse Information.

    Concerned with clarifying some of the more complex issues in drug abuse, the National Clearinghouse for Drug Abuse Information has prepared this special report on the British narcotics system. Underlying the British approach is the belief that narcotic dependence is a medical problem to be treated by medical professionals rather than a criminal…

  3. National Clearinghouse for Drug Abuse Information Report Series, Series 18, No. 1.

    ERIC Educational Resources Information Center

    National Inst. on Drug Abuse (DHEW/PHS), Rockville, MD. National Clearinghouse for Drug Abuse Information.

    Concerned with clarifying some of the more complex issues in drug abuse, the National Clearinghouse for Drug Abuse Information has prepared this special report on methaqualone. Background information is provided through a summary of its history, legal status, and the opinions of authorities in the field. Significant research on the subject is…

  4. National Clearinghouse for Drug Abuse Information Report Series, Series 16, No. 1.

    ERIC Educational Resources Information Center

    National Inst. on Drug Abuse (DHEW/PHS), Rockville, MD. National Clearinghouse for Drug Abuse Information.

    Concerned with clarifying some of the more complex issues in drug abuse, the National Clearinghouse for Drug Abuse Information has prepared this special report on psilocybin. Background information is provided through a summary of its history, legal status, and the opinions of authorities in the field. Significant research on the subject is…

  5. 78 FR 10185 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-02-13

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special...

  6. 77 FR 14023 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-08

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special...

  7. 76 FR 22715 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special...

  8. 75 FR 36660 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-28

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special...

  9. 76 FR 22717 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-22

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special...

  10. 76 FR 32978 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-07

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special...

  11. 77 FR 28889 - National Institute on Alcohol Abuse and Alcoholism Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-16

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special...

  12. 77 FR 14024 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-08

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special...

  13. 77 FR 26770 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-07

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special...

  14. 75 FR 37818 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special...

  15. 77 FR 61769 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special...

  16. The Trial of the Expert Witness: Negotiating Credibility in Child Abuse Correspondence

    ERIC Educational Resources Information Center

    Schryer, Catherine F.; Afros, Elena; Mian, Marcellina; Spafford, Marlee; Lingard, Lorelei

    2009-01-01

    This article reports on forensic letters written by physicians specializing in identifying children who have experienced maltreatment. These writers face an extraordinary exigence in that they must provide an opinion as to whether a child has experienced abuse without specifically diagnosing abuse and thus crossing into a legal domain. Their…

  17. National Clearinghouse for Drug Abuse Information Report Series, Series 26, No. 1.

    ERIC Educational Resources Information Center

    National Inst. on Drug Abuse (DHEW/PHS), Rockville, MD. National Clearinghouse for Drug Abuse Information.

    Concerned with clarifying some of the more complex issues in drug abuse, the National Clearinghouse for Drug Abuse Information has prepared this special report on narcotic antagonists, particularly nalorphine, naloxone, cyclazocine, levallorphan, and pentazocine. Background information is provided through a summary of their history, legal status,…

  18. National Clearinghouse for Drug Abuse Information Report Series, Series 14, No. 1.

    ERIC Educational Resources Information Center

    National Inst. on Drug Abuse (DHEW/PHS), Rockville, MD. National Clearinghouse for Drug Abuse Information.

    Concerned with clarifying some of the more complex issues in drug abuse, the National Clearinghouse for Drug Abuse Information has prepared this special report on phencyclidine (PCP). Background information is provided through a summary of its history, legal status, and the opinions of authorities in the field. Significant research on the subject…

  19. National Clearinghouse for Drug Abuse Information Report Series, Series 12, No. 1.

    ERIC Educational Resources Information Center

    National Inst. on Drug Abuse (DHEW/PHS), Rockville, MD. National Clearinghouse for Drug Abuse Information.

    Concerned with clarifying some of the more complex issues in drug abuse, the National Clearinghouse for Drug Abuse Information has prepared this special report on methadone. Background information is provided through a summary of its history, legal status, and the opinions of authorities in the field. Significant research on the subject is…

  20. National Clearinghouse for Drug Abuse Information Report Series, Series 11, No. 1.

    ERIC Educational Resources Information Center

    National Inst. on Drug Abuse (DHEW/PHS), Rockville, MD. National Clearinghouse for Drug Abuse Information.

    Concerned with clarifying some of the more complex issues in drug abuse, the National Clearinghouse for Drug Abuse Information has prepared this special report on cocaine. Background information is provided through a summary of its history, legal status, and the opinions of authorities in the field. Significant research on the subject is presented…

  1. National Clearinghouse for Drug Abuse Information Report Series, Series 25, No. 1.

    ERIC Educational Resources Information Center

    National Inst. on Drug Abuse (DHEW/PHS), Rockville, MD. National Clearinghouse for Drug Abuse Information.

    Concerned with clarifying some of the more complex issues in drug abuse, the National Clearinghouse for Drug Abuse Information has prepared this special report on methylenedioxyamphetamine (MDA), commonly called Mellow Drug of America. Background information is provided through a summary of its history, legal status, and the opinions of…

  2. National Clearinghouse for Drug Abuse Information Report Series, Series 15, No. 1.

    ERIC Educational Resources Information Center

    National Inst. on Drug Abuse (DHEW/PHS), Rockville, MD. National Clearinghouse for Drug Abuse Information.

    Concerned with clarifying some of the more complex issues in drug abuse, the National Clearinghouse for Drug Abuse Information has prepared this special report on mescaline. Background information is provided through a summary of its history, legal status, and the opinions of authorities in the field. Significant research on the subject is…

  3. 78 FR 63483 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-24

    ... HUMAN SERVICES National Institutes of Health National Institute on Alcohol Abuse and Alcoholism; Notice... of personal privacy. Name of Committee: National Institute on Alcohol Abuse and Alcoholism Special... shutdown of October 2013. (Catalogue of Federal Domestic Assistance Program No. 93.273, Alcohol...

  4. 77 FR 64117 - National Institute on Drug Abuse; Amended Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-18

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute on Drug Abuse; Amended Notice of Meeting Notice is hereby given of changes in the meeting of the National Institute on Drug Abuse Special...

  5. Abuse of medications that theoretically are without abuse potential.

    PubMed

    Reeves, Roy R; Ladner, Mark E; Perry, Candace L; Burke, Randy S; Laizer, Janet T

    2015-03-01

    The potential for abuse of medications that are controlled substances is well known. Abuse of certain noncontrolled prescription drugs and over-the-counter medications also may occur. To some degree, any medication that exerts psychoactive effects may be abused if taken in high enough doses or by means that result in high serum or cerebrospinal fluid levels. Many clinicians may be unaware of the potential for abuse of these medications. This review examines evidence of the possibility of abuse of several common medications that theoretically do not have abuse potential, including cough and cold preparations, antihistamines, anticholinergics, antipsychotics, antidepressants, anticonvulsants, skeletal muscle relaxants, and antiemetics. Means by which such medications may be abused and biochemical and physiological mechanisms fostering their abuse also are discussed.

  6. Emerging drugs of abuse.

    PubMed

    Nelson, Michael E; Bryant, Sean M; Aks, Steven E

    2014-02-01

    Many new emerging drugs of abuse are marketed as legal highs despite being labeled "not for human consumption" to avoid regulation. The availability of these substances over the Internet and in "head shops" has lead to a multitude of emergency department visits with severe complications including deaths worldwide. Despite recent media attention, many of the newer drugs of abuse are still largely unknown by health care providers. Slight alterations of the basic chemical structure of substances create an entirely new drug no longer regulated by current laws and an ever-changing landscape of clinical effects. The purity of each substance with exact pharmacokinetic and toxicity profiles is largely unknown. Many of these substances can be grouped by the class of drug and includes synthetic cannabinoids, synthetic cathinones, phenethylamines, as well as piperazine derivatives. Resultant effects generally include psychoactive and sympathomimetic-like symptoms. Additionally, prescription medications, performance enhancing medications, and herbal supplements are also becoming more commonly abused. Most new drugs of abuse have no specific antidote and management largely involves symptom based goal directed supportive care with benzodiazepines as a useful adjunct. This paper will focus on the history, epidemiology, clinical effects, laboratory analysis, and management strategy for many of these emerging drugs of abuse.

  7. [Methods of substance abuse prevention in the Armed Forces].

    PubMed

    Fisun, A Ia; Shamreĭ, V K; Marchenko, A A; Sinenchenko, A G; Pastushenkov, A V

    2013-09-01

    Dynamics of substance abuse morbidity in the Armed Forces of the Russian Federation during the last 10 years (2002-2012) was analyzed. Results of performed analysis showed decreasing tendency since 2007 in conscripts (0.07% in 2012) and in contract soldiers (0.3% in 2012). Alcoholism prevailed in the structure of substance abuse in conscripts (0.05%), drug abuses were diagnosed 2,5 times less often (0.02%). In contract soldiers non-alcohol abuses were diagnosed in 0.004% of cases. It is stated that the major aims of substance abuse prevention are qualitative recruiting of military units (especially in troops maintaining the combat readiness) and departments (subunits) of military education, creating conditions for propaganda for healthy lifestyle, prohibition of drugs and psychopharmaceuticals in military units. For early detection of persons liable to substance abuse and facts of drug consumption it is necessary to perform a medical examination with the help of special program apparatus complex (such as "Addicts") and take into account clinical signs of addiction. Besides, it is necessary to introduce planned and unexpected medical examinations of servicemen. Algorithm of measures in case of detection of serviceman with alcohol or drug intoxication is given. In conclusion the main organizational principals of substance abuse prevention in the Armed Forces are given.

  8. Child abuse by burning--an index of suspicion.

    PubMed

    Purdue, G F; Hunt, J L; Prescott, P R

    1988-02-01

    Although general awareness of child abuse is increasing, abuse by burning is often unrecognized. Seventy-one consecutive children admitted with inflicted burns were studied. Mean age was 1.8 yrs and mean burn size was 13.5%. Mean length of stay was 18.9 days. Scalds (83% from tap water) were the most frequent cause of injury. An immersion pattern was present in 59%; six patients had a classic forced immersion injury. Fourteen children had nonburn trauma. Four patients died: all had tap water immersion burns. Inflicted burns are usually manifested by characteristic patterns of injury, which must be correlated with the given history. When compared with accidentally burned children, abused children were significantly younger, had longer hospital stays, and had a higher mortality. A team approach to child abuse with the addition of a specially trained group is important to insure prompt recognition, more objective appraisals, and further followup.

  9. How Do People with Intellectual Disabilities View Abuse and Abusers?

    ERIC Educational Resources Information Center

    Northway, Ruth; Melsome, Melissa; Flood, Samantha; Bennett, Davey; Howarth, Joyce; Thomas, Becki

    2013-01-01

    People with intellectual disabilities have a higher risk of being abused than other people, but to date research has not explored their views regarding abuse. This article reports the findings relating to one question within a participatory research study concerning the abuse of people with intellectual disabilities. This question asked what…

  10. Substance abuse and child maltreatment.

    PubMed

    Wells, Kathryn

    2009-04-01

    Pediatricians and other medical providers caring for children need to be aware of the dynamics in the significant relationship between substance abuse and child maltreatment. A caregiver's use and abuse of alcohol, marijuana, heroin, cocaine, methamphetamine, and other drugs place the child at risk in multiple ways. Members of the medical community need to understand these risks because the medical community plays a unique and important role in identifying and caring for these children. Substance abuse includes the abuse of legal drugs as well as the use of illegal drugs. The abuse of legal substances may be just as detrimental to parental functioning as abuse of illicit substances. Many substance abusers are also polysubstance users and the compounded effect of the abuse of multiple substances may be difficult to measure. Often other interrelated social features, such as untreated mental illness, trauma history, and domestic violence, affect these families.

  11. She knows what's comingIn order to act against elder abuse, health professionals must be trained in what to look for. Joanna Lyall reports on a campaign launch that is asking nurses to take action.

    PubMed

    Lyall, Joanna

    2007-03-01

    Abuse of older people needs to be given the same priority as child abuse, with special training for all frontline staff, according to Help the Aged, which has launched a campaign to highlight the issue.

  12. Local and National Outcomes from Community Partnerships to Prevent Substance Abuse.

    ERIC Educational Resources Information Center

    Yin, Robert K., Ed.

    1997-01-01

    Outcomes evaluation of community partnerships to prevent substance abuse poses many methodological challenges. The nine articles of this special section illustrate the variety of approaches evaluators have taken to studies that are often complicated because of small sample size. (SLD)

  13. Chronic time abuse.

    PubMed

    Berglas, Steven

    2004-06-01

    Anyone who has ever managed people who abuse time--whether they are chronic procrastinators or individuals who work obsessively to meet deadlines weeks in advance--knows how disruptive they can be to a business's morale and operating efficiency. But lessons in time management will have no impact on these employees. That's because real time abuse results from psychological conflict that neither a workshop nor a manager's cajoling can cure. Indeed, the time abuser's quarrel isn't even with time but rather with a brittle self-esteem and an unconscious fear of being evaluated and found wanting. This article describes four types of time abusers typically encountered in the workplace: Perfectionists are almost physically afraid of receiving feedback. Their work has to be "perfect," so they can increase their likelihood of earning a positive evaluation or at least avoid getting a negative one. Preemptives try to be in control by handing in work far earlier than they need to, making themselves unpopular and unavailable in the process. People pleasers commit to far too much work because they find it impossible to say no. Procrastinators make constant (and often reasonable-sounding) excuses to mask a fear of being found inadequate in their jobs. Managing these four types of people can be challenging, since time abusers respond differently from most other employees to criticism and approval. Praising a procrastinator when he is on time, for instance, will only exacerbate the problem, because he will fear that your expectations are even higher than before. In fact, some time abusers, like the perfectionist, may need professional treatment. This article will give you insight into why they are the way they are--and what can be done to help them manage their problems.

  14. Vaccines against drug abuse.

    PubMed

    Shen, X Y; Orson, F M; Kosten, T R

    2012-01-01

    The currently available medications for the treatment of drug abuse have had only limited success. Anti-addiction vaccines, aimed at eliciting antibodies that block the pharmacological effects of drugs, have great potential for treating drug abuse. We review the status of two vaccines that are undergoing clinical trials (for cocaine and nicotine addiction) and two that are still in preclinical development (for methamphetamine and heroin addiction). We also outline the challenges and ethical concerns associated with the development of anti-addiction vaccines and their use as future therapeutics.

  15. Diagnostic imaging of child abuse.

    PubMed

    2009-05-01

    The role of imaging in cases of child abuse is to identify the extent of physical injury when abuse is present and to elucidate all imaging findings that point to alternative diagnoses. Effective diagnostic imaging of child abuse rests on high-quality technology as well as a full appreciation of the clinical and pathologic alterations occurring in abused children. This statement is a revision of the previous policy published in 2000.

  16. Israeli Perspectives on Elder Abuse

    ERIC Educational Resources Information Center

    Rabi, Keren

    2006-01-01

    Despite the prevailing agreement among researchers that the increasing rate of elder abuse in Israel is relatively understudied, not sufficiently identified, and not appropriately addressed, literature on elderly abuse in the Israeli society remains limited. The common discourse on aging, eldercare, and elder abuse and neglect, mainly revolves…

  17. Child Abuse: Betrayal and Disclosure

    ERIC Educational Resources Information Center

    Foynes, Melissa Ming; Freyd, Jennifer J.; DePrince, Anne P.

    2009-01-01

    Objective: The current study tested several hypotheses about disclosure of childhood sexual, physical, and emotional abuse derived from Betrayal Trauma Theory [Freyd, J. J. (1996). Betrayal trauma: The logic of forgetting childhood abuse. Cambridge, MA: Harvard University Press]. We predicted that the duration of time from abuse to its disclosure…

  18. Literature Review of Sexual Abuse.

    ERIC Educational Resources Information Center

    DePanfilis, Diane

    This document provides a review of recent, state-of-the-art literature concerning the nature, extent, dynamics, and effects of child sexual abuse and examines America's preventive intervention and treatment efforts for child sexual abuse. After an extensive presentation of the problems of defining terms in sexual abuse, these topics are discussed:…

  19. Child Abuse and Developmental Disabilities.

    ERIC Educational Resources Information Center

    Grayson, Joann, Ed.; Bartlette, Don

    1992-01-01

    Literature indicating high rates of abuse in this population is reviewed, as is literature indicating high rates of developmental disabilities in child victims of abuse. Problems in data collecting practices are noted. Reasons for these children's greater risk for abuse are identified, including child attributes, stress, parent vulnerabilities,…

  20. Child Abuse Prevention Handbook. Revised.

    ERIC Educational Resources Information Center

    California State Office of the Attorney General, Sacramento. Crime Prevention Center.

    Intended to heighten public awareness and provide practical information to professionals, this handbook defines and describes child abuse (including sexual abuse) and its associated signs and injuries. The societal and family environments in which child abuse most typically occurs are described, and the California penal code sections pertaining to…

  1. Childhood Sexual Abuse and Suicide

    MedlinePlus

    ... Abuse: Research, Treatment, & Program Innovations for Victims, Survivors, & Offenders, 14(4), 1-24. doi: 10.1300/J070v14n04_ ... 1996). Childhood sexual abuse and psychiatric disorder in young adulthood: Psychiatric outcomes of childhood sexual abuse. Journal ...

  2. Geriatric Alcoholism and Drug Abuse

    ERIC Educational Resources Information Center

    Schuckit, Marc A.

    1977-01-01

    This paper reviews the literature and presents new data on alcohol and drug problems in older individuals. Drug abusers include users of opiates, inadvertent misusers, and deliberate abusers of nonopiates. Two to 10 percent of the elderly are alcoholic, and these are usually individuals beginning alcohol abuse after age 40. (Author)

  3. Recognizing the adolescent drug abuser.

    PubMed

    MacKenzie, R G; Jacobs, E A

    1987-03-01

    Adolescents are at high risk for using and abusing illicit drugs. Guidelines for recognizing drug abusers are presented as well as a staging process for progression of drug use. The family physician is in an ideal position to identify young users/abusers and to assist them and their families in obtaining much needed assistance.

  4. The Drug-Abuse Questionnaire.

    ERIC Educational Resources Information Center

    Ferneau, E.; Mueller, S.

    The drug-abuse questionnaire used to survey college student attitudes on the subject is provided. It is identical to the alcoholism questionnaire except for word changes appropriate to the subject matter. The questionnaire consists of 40 statements about drug abuse and drug abusers, with 7 possible responses: (1) completely disagree; (2) mostly…

  5. Intravenous methylphenidate abuse. Prototype for prescription drug abuse.

    PubMed

    Parran, T V; Jasinski, D R

    1991-04-01

    Data are presented from a case series of 22 patients who abused methylphenidate hydrochloride (Ritalin-SR). The abuse pattern and symptoms of toxicity were similar to that seen with cocaine hydrochloride and amphetamine sulfate addiction; yet, the morbidity and mortality seen in this case series were greater than usual for a group of patients involved in intravenous drug abuse. We describe the characteristics of the methylphenidate abuse syndrome in terms of the pharmacology of methylphenidate, the constituents of the Ritalin-SR preparation, and the disease of chemical dependence. We propose solutions to the problem of methylphenidate abuse.

  6. Cognitive and Emotional Differences between Abusive and Non-Abusive Fathers

    ERIC Educational Resources Information Center

    Francis, Karen J.; Wolfe, David A.

    2008-01-01

    Objective: Abusive fathers perpetrate a substantial portion of child physical abuse. Despite this, little is known about how they differ from non-abusive fathers. This study compared a broad range of cognitive and affective factors between physically abusive and non-abusive fathers. Methods: Abusive (n = 24) and non-abusive (n = 25) fathers…

  7. Abuse Characteristics and Psychiatric Consequences Associated with Online Sexual Abuse.

    PubMed

    Say, Gökçe Nur; Babadağı, Zehra; Karabekiroğlu, Koray; Yüce, Murat; Akbaş, Seher

    2015-06-01

    The current study examined the rate and psychiatric correlates of sexual abuse involving the use of digital technologies by the offender in a wide sample of juvenile victims. Sociodemographic, abuse, and psychiatric characteristics of 662 sexually abused children and adolescents were evaluated. Of these, 93 reported that digital devices were used by the offender in several ways to facilitate the sexual abuse. The offender-victim relationship was initiated through the Internet in 39 victims. Involvement of digital technologies in sexual abuse was significantly associated with penetrative and recurrent form of sexual abuse commited by multiple offenders with coexisting violence. Additionally, victims of sexual abuse with a digital component were 4.21 times more likely to develop any psychopathology, 3.77 times more likely to have depression, and 2.14 times more likely to have post-traumatic stress disorder as a result of sexual abuse. These results indicated that the offender's use of digital technology may aid the initiation and facilitation of the sexual abuse of youths and may relate to more severe outcomes. This study revealed the importance of raising the awareness of professionals and the community about the potential risks associated with digital technologies and sexual abuse. Mental health professionals should consider this additional form of victimization, especially when dealing with sexual abuse victims.

  8. Special Education through Neighbourhood Centers in Algeria.

    ERIC Educational Resources Information Center

    Boucebci, Mahfoud

    1981-01-01

    The article provides a survey of special education needs in Algeria with emphasis on the role of neighborhood centers which involve parents in the education of mentally handicapped children. Journal availability: see EC 133 861. (DB)

  9. Software Publication Considerations and Special Education.

    ERIC Educational Resources Information Center

    Fuchs, Victor E.

    1982-01-01

    Market factors surrounding computer software in special education are examined, including proliferation of computers in schools, widespread marketing and distribution patterns for software, consumer demands for software, quality, timelessness, emphasis on basic skills, and an understanding of future capabilities. (CL)

  10. Special Days, Special Ways.

    ERIC Educational Resources Information Center

    Clarke, Jacqueline

    2001-01-01

    Presents unique ways to create special rituals that recognize individual students' achievements and milestones. Ideas include throwing a send-off party for a student who is moving; holding monthly birthday luncheons; choosing an ambassador to accompany new students around school; and making a lost tooth container that students can use to safely…

  11. Educating against Drug Abuse.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France).

    This book is a compilation of drug education and drug abuse prevention materials collected by United Nations Educational, Scientific and Cultural Organization (UNESCO) along with example of activities carried out by various countries. It opens with four introductory papers by separate authors: (1) "Prevention of Drug Dependence: A Utopian…

  12. Drug and Substance Abuse

    MedlinePlus

    ... Adults Making Your Wishes Known Home & Community Home › Aging & Health A to Z › Drug and Substance Abuse Font size A A A Print Share Glossary Basic Facts & Information Causes & Symptoms Diagnosis & Tests Care & Treatment Lifestyle & Management Other Resources Caregiving How ...

  13. Substance Abuse and Counseling.

    ERIC Educational Resources Information Center

    Sales, Amos, Ed.

    This book focuses on the identification of practical knowledge and skills needed for counseling individuals with substance abuse problems. It is a resource for practitioners, students, and faculty in school counseling, rehabilitation counseling, mental health counseling, school psychology, or social work in recognizing, preventing, and treating…

  14. Handbook On Drug Abuse.

    ERIC Educational Resources Information Center

    Dupont, Robert I.; And Others

    A decade of professional research on drug abuse has produced both an abundance of materials and a vocabulary that is not shared by planners, clinicians, and policy makers. This handbook compiles the major developments of the period and their treatment and research implications in a style intended to be understood by all three types of…

  15. New drugs of abuse.

    PubMed

    Rech, Megan A; Donahey, Elisabeth; Cappiello Dziedzic, Jacqueline M; Oh, Laura; Greenhalgh, Elizabeth

    2015-02-01

    Drug abuse is a common problem and growing concern in the United States, and over the past decade, novel or atypical drugs have emerged and have become increasingly popular. Recognition and treatment of new drugs of abuse pose many challenges for health care providers due to lack of quantitative reporting and routine surveillance, and the difficulty of detection in routine blood and urine analyses. Furthermore, street manufacturers are able to rapidly adapt and develop new synthetic isolates of older drugs as soon as law enforcement agencies render them illegal. In this article, we describe the clinical and adverse effects and purported pharmacology of several new classes of drugs of abuse including synthetic cannabinoids, synthetic cathinones, salvia, desomorphine, and kratom. Because many of these substances can have severe or life-threatening adverse effects, knowledge of general toxicology is key in recognizing acute intoxication and overdose; however, typical toxidromes (e.g., cholinergic, sympathomimetic, opioid, etc.) are not precipitated by many of these agents. Medical management of patients who abuse or overdose on these drugs largely consists of supportive care, although naloxone may be used as an antidote for desomorphine overdose. Symptoms of aggression and psychosis may be treated with sedation (benzodiazepines, propofol) and antipsychotics (haloperidol or atypical agents such as quetiapine or ziprasidone). Other facets of management to consider include treatment for withdrawal or addiction, nutrition support, and potential for transmission of infectious diseases.

  16. How to Handle Abuse

    MedlinePlus

    ... hurting or harming someone) might have frightened the boy or girl into staying quiet. No matter what the abuser ... suit or underwear: breasts, vagina, and bottom for girls, and penis and bottom for boys. If an adult or another kid touches a ...

  17. Understanding Fatal Child Abuse.

    ERIC Educational Resources Information Center

    Hicks, Ralph A.; Gaughan, Daniel C.

    1995-01-01

    Medical, social service, and coroner reports were reviewed for 14 cases of fatal child abuse and neglect identified at a children's hospital from 1988 to 1992. Median age was 6.5 months. Six families had prior protective service involvement (though four of these had involved a sibling). The cause of death in all cases was blunt impact head injury.…

  18. Drug abuse and addiction.

    PubMed

    Nessa, A; Latif, S A; Siddiqui, N I; Hussain, M A; Hossain, M A

    2008-07-01

    Among the social and medical ills of the twentieth century, substance abuse ranks as on one of the most devastating and costly. The drug problem today is a major global concern including Bangladesh. Almost all addictive drugs over stimulate the reward system of the brain, flooding it with the neurotransmitter dopamine. That produces euphoria and that heightened pleasure can be so compelling that the brain wants that feeling back again and again. However repetitive exposure induces widespread adaptive changes in the brain. As a consequence drug use may become compulsive. An estimated 4.7% of the global population aged 15 to 64 or 184 million people, consume illicit drug annually. Heroin use alone is responsible for the epidemic number of new cases of HIV/AIDS, Hepatitis and drug addicted infant born each year. Department of narcotic control (DNC) in Bangladesh reported in June 2008 that about 5 million drug addicts in the country & addicts spend at least 17 (Seventeen) billion on drugs per year. Among these drug addicts, 91% are young and adolescents population. Heroin is the most widely abused drugs in Bangladesh. For geographical reason like India, Pakistan and Myanmar; Bangladesh is also an important transit root for internationally trafficking of illicit drug. Drug abuse is responsible for decreased job productivity and attendance increased health care costs, and escalations of domestic violence and violent crimes. Drug addiction is a preventable disease. Through scientific advances we now know much more about how exactly drugs work in the brain, and we also know that drug addiction can be successfully treated to help people stop abusing drugs and resume their productive lives. Most countries have legislation designed to criminalize some drugs. To decrease the prevalence of this problem in our setting; increase awareness, promoting additional research on abused and addictive drugs, and exact implementation of existing laws are strongly recommended. We should

  19. MDMA ("ecstasy") abuse as an example of dopamine neuroplasticity.

    PubMed

    Schenk, Susan

    2011-04-01

    A number of reviews have focused on the short- and long-term effects of MDMA and, in particular, on the persistent deficits in serotonin neurotransmission that accompany some exposure regimens. The mechanisms underlying the serotonin deficits and their relevance to various behavioral and cognitive consequences of MDMA use are still being debated. It has become clear, however, that some individuals develop compulsive and uncontrolled drug-taking that is consistent with abuse. For other drugs of abuse, this transition has been attributed to neuroadaptations in central dopamine mechanisms that occur as a function of repeated drug exposure. A question remains as to whether similar neuroadaptations occur as a function of exposure to MDMA and the impact of serotonin neurotoxicity in the transition from use to abuse. This review focuses specifically on this issue by first providing an overview of human studies and then reviewing the animal literature with specific emphasis on paradigms that measure subjective effects of drugs and self-administration as indices of abuse liability. It is suggested that serotonin deficits resulting from repeated exposure to MDMA self-administration lead to a sensitized dopaminergic response to the drug and that this sensitized response renders MDMA comparable to other drugs of abuse.

  20. "Who can you tell?" Features of Arab culture that influence conceptualization and treatment of childhood sexual abuse.

    PubMed

    Haboush, Karen L; Alyan, Hala

    2013-01-01

    The literature on child sexual abuse reflects growing recognition of the manner in which culture impacts the conceptualization, experience, and treatment of such cases. Despite heightened visibility of Arab Americans within the United States, population due to recent media attention, little empirical research exists on the occurrence of child sexual abuse within this population. Arab culture is often characterized by an emphasis on collectivism and familial obligations, and such features may prove to either facilitate or impede assessment and treatment of child sexual abuse, depending on how they are manifested. In terms of reporting child sexual abuse, cultural values pertaining to shame and honor as well as the stigma attached to mental health problems may influence the response to abuse. As such, enhancing the cultural competence of the therapist is key to facilitating effective cultural practice. Empirical research is required to investigate and substantiate these concepts as they relate to child sexual abuse in Arab-American populations.

  1. Homeless Youths' Caretakers: The Mediating Role of Childhood Abuse on Street Victimization and Housing Instability.

    PubMed

    Slesnick, Natasha; Zhang, Jing; Brakenhoff, Brittany

    2016-04-01

    Homeless youths who live on the streets are particularly vulnerable to victimization and continued homelessness. Identifying factors associated with housing stability and victimization while homeless can offer useful guidance for those who serve these youths. The current study examined the relationship between multiple caretakers and the unique effect of childhood abuse (physical, sexual, neglect) on past-year housing and victimization experiences. Seventy-nine substance-using, street-living youths ages 14 to 24 years completed the survey. Findings confirmed a relationship between multiple caretaker transitions and childhood sexual abuse and neglect, but not physical abuse. Sexual abuse was further associated with higher street victimization and reduced housing stability. In addition, sexual abuse mediated the relationship between multiple caretakers and past-year victimization and housing instability. These findings suggest that sexually abused homeless youths are at particular risk for future victimization and housing instability compared with other youths, and specialized intervention for these youths is indicated.

  2. Substance Abuse Screening

    MedlinePlus

    ... Valium, Serepax, Rohypnol, etc.) h. Hallucinogens (LSD, acid, mushrooms, PCP, Special K, etc.) i. Opioids (heroin, morphine, ... Valium, Serepax, Rohypnol, etc.) h. Hallucinogens (LSD, acid, mushrooms, PCP, Special K, etc.) i. Opioids (heroin, morphine, ...

  3. Brainwashing and battering fatigue. Psychological abuse in domestic violence.

    PubMed

    Mega, L T; Mega, J L; Mega, B T; Harris, B M

    2000-01-01

    Intimate partner violence occurs often in the United States; it involves an interrelated combination of physical, sexual, and psychological abuse, usually directed against women. The psychological aspect deserves special attention because victims who lose their independence, self-esteem, and dignity tend to remain in abusive situations. The abuse is perpetrated by a domestic partner to maintain power and control in the relationship. To assert control, the abuser uses "brainwashing tactics" similar to those used on prisoners of war, hostages, or members of a cult. Common features of brainwashing include isolation, humiliation, accusation, and unpredictable attacks. The abusive environment produces real and anticipated fear, which contributes to the battered woman's belief that her situation is hopeless and that she must depend on her abuser. She develops coping strategies to deal with her oppressive environment, but eventually exhibits symptoms of "battering fatigue," similar to the battle fatigue of soldiers in combat who, like battered women, live in fear of being killed or severely injured. Recognizing the state of mind of these women can help us understand why it is difficult for them to flee their traumatic environment and why they may resort to suicide or homicide. For healthcare providers to screen and treat their patients adequately, it is imperative that they appreciate the complex and devastating psychological aspects of domestic violence.

  4. Physical abuse in low-income women in Aleppo, Syria.

    PubMed

    Maziak, Wasim; Asfar, Taghrid

    2003-04-01

    Violence against women is a vicious practice present in all societies. Yet data about its occurrence and associated factors are scarce in the Arab world. In this study, we attempt to determine the spread of physical abuse and its sociodemographic correlates among low-income women in Aleppo, Syria. A sample of 411 women was recruited from 8 randomly selected primary care centers in Aleppo. Response rate was 97%, mean age of participants 28 +/- 8 years, and most women (88%) were married. A special questionnaire was used including questions about physical abuse, the self-reporting questionnaire (SRQ-20), and questions about relevant sociodemographic information. Current physical abuse (battering at least 3 times during the previous year) was found in 23% of the investigated and among 26% of married women, while regular abuse (battering at least once weekly) was found in 3.3% of married women. Correlates of physical abuse were women's education, religion, age, marital status, economic status, mental distress, smoking, and residence. Our data show that physical abuse is prevalent in this population and that women's education is the most important modifiable factor.

  5. Substance abuse among individuals with intellectual disabilities.

    PubMed

    Carroll Chapman, Shawna L; Wu, Li-Tzy

    2012-01-01

    Individuals with disabilities are a growing population that confronts multiple disadvantages from social and environmental determinants of health. In particular, the 7-8 million people in the U.S. with an intellectual disability (ID) suffer disproportionately from substance use problems, largely because of a lack of empirical evidence to inform prevention and treatment efforts for them. Although available research could inform future research efforts, studies are scattered across disciplines with the last review synthesizing findings written more than five years ago. To consider more recent findings with earlier works, PubMed, PsychINFO, and Google Scholar were searched and produced 37 peer-reviewed texts across multiple disciplines, 15 from 2006 or later. While the prevalence of alcohol and illicit drug use in this population are low, the risk of having a substance-related problem among ID substance users is comparatively high. Gaps in the research and population subgroups that warrant special attention are identified, such as individuals with borderline and mild ID, individuals with co-occurring mental illness, and individuals who are incarcerated. Compared with substance abusers without ID, ID substance abusers are less likely to receive substance abuse treatment or remain in treatment. Research is needed to better gauge the magnitude of substance use problems, identify prevention strategies, and specify treatment components that meet the unique needs of individuals with ID.

  6. Abuse Tolerance Improvements

    SciTech Connect

    Orendorff, Christopher J.; Nagasubramanian, Ganesan; Fenton, Kyle R.; Allcorn, Eric

    2015-10-01

    As lithium-ion battery technologies mature, the size and energy of these systems continues to increase (> 50 kWh for EVs); making safety and reliability of these high energy systems increasingly important. While most material advances for lithium-ion chemistries are directed toward improving cell performance (capacity, energy, cycle life, etc.), there are a variety of materials advancements that can be made to improve lithium-ion battery safety. Issues including energetic thermal runaway, electrolyte decomposition and flammability, anode SEI stability, and cell-level abuse tolerance continue to be critical safety concerns. This report highlights work with our collaborators to develop advanced materials to improve lithium-ion battery safety and abuse tolerance and to perform cell-level characterization of new materials.

  7. Drug abuse and stroke.

    PubMed

    Fonseca, Ana Catarina; Ferro, José M

    2013-02-01

    Cerebrovascular disorders contribute to the morbidity and disability associated with illicit drug use. Drug abusers have an increased risk of both hemorrhagic and ischemic stroke. In geographic areas with a high prevalence of illicit drug use, drug abuse is a frequent cause of stroke in the young adult. The illicit drugs more commonly associated with stroke are psychomotor stimulants, such as amphetamine and cocaine. Less commonly implicated are opioids and psychotomimetic drugs, including cannabis. Toxicology screening for illicit drugs should be done in young patients with stroke with no obvious cause, or if suggested by history or examination. Although in some patients the mechanism of stroke is identified using neuroimaging and other modern diagnostic tools, in a sizeable fraction of cases the mechanism of stroke remains unclear. Further studies are needed to elucidate the role of hemodynamic and immunologic mechanisms in these cases.

  8. Substance Abuse and Trauma.

    PubMed

    Simmons, Shannon; Suárez, Liza

    2016-10-01

    There is a strong, bidirectional link between substance abuse and traumatic experiences. Teens with cooccurring substance use disorders (SUDs) and posttraumatic stress disorder (PTSD) have significant functional and psychosocial impairment. Common neurobiological foundations point to the reinforcing cycle of trauma symptoms, substance withdrawal, and substance use. Treatment of teens with these issues should include a systemic and integrated approach to both the SUD and the PTSD.

  9. Correlates of joint child protection and police child sexual abuse investigations: results from the Canadian Incidence Study of Reported Child Abuse and Neglect–2008

    PubMed Central

    Tonmyr, L.; Gonzalez, A.

    2015-01-01

    Abstract Introduction: Our study examines the frequency of joint investigations by child protection workers and the police in sexual abuse investigations compared to other maltreatment types and the association of child-, caregiver-, maltreatment- and investigation-related characteristics in joint investigations, focussing specifically on investigations involving sexual abuse. Methods: We analyzed data from the Canadian Incidence Study of Reported Child Abuse and Neglect–2008 using logistic regression. Results: The data suggest that sexual abuse (55%), and then physical abuse, neglect and emotional maltreatment, are most often co-investigated. Substantiation of maltreatment, severity of maltreatment, placement in out-of-home care, child welfare court involvement and referral of a family member to specialized services was more likely when the police were involved in an investigation. Conclusion: This study adds to the limited information on correlates of joint child protection agency and police investigations. Further research is needed to determine the effectiveness of these joint investigations. PMID:26605560

  10. The Library and New Research Emphasis: Political and Financial Problems with Building a Research Base.

    ERIC Educational Resources Information Center

    Buschman, John

    This paper explores issues related to the degree to which weight and emphasis are given in higher education hiring and promotion practices to research versus teaching and service. In particular it examines the special problems posed by research demands in traditionally non-research universities. Noting that one of the most significant…

  11. Drug abuse in athletes

    PubMed Central

    Reardon, Claudia L; Creado, Shane

    2014-01-01

    Drug abuse occurs in all sports and at most levels of competition. Athletic life may lead to drug abuse for a number of reasons, including for performance enhancement, to self-treat otherwise untreated mental illness, and to deal with stressors, such as pressure to perform, injuries, physical pain, and retirement from sport. This review examines the history of doping in athletes, the effects of different classes of substances used for doping, side effects of doping, the role of anti-doping organizations, and treatment of affected athletes. Doping goes back to ancient times, prior to the development of organized sports. Performance-enhancing drugs have continued to evolve, with “advances” in doping strategies driven by improved drug testing detection methods and advances in scientific research that can lead to the discovery and use of substances that may later be banned. Many sports organizations have come to ban the use of performance-enhancing drugs and have very strict consequences for people caught using them. There is variable evidence for the performance-enhancing effects and side effects of the various substances that are used for doping. Drug abuse in athletes should be addressed with preventive measures, education, motivational interviewing, and, when indicated, pharmacologic interventions. PMID:25187752

  12. Culturally competent substance abuse treatment with transgender persons.

    PubMed

    Nuttbrock, Larry A

    2012-01-01

    Transgender individuals are misunderstood and inadequately treated in many conventional substance abuse treatment programs. This article reviews current concepts regarding the definition and diversity of transgenderism and summarizes the existing literature on the prevalence and correlates of substance use in transgendered populations. Examples of culturally competent and gender-sensitive treatment in specialized settings are cited, with a call to extend these initiatives throughout the gamut of service venues that engage transgender individuals. Cultural competence combined with gender sensitivity should improve the effectiveness of substance abuse treatment for transgender individuals and will contribute to the goal of providing effective services in an increasingly diverse society.

  13. Drugs of Abuse in Meconium.

    PubMed

    Moore, C; Negrusz, N

    1995-12-01

    The determination of fetal drug exposure is of great importance for the future development of the neonate. Meconium, the first fecal material excreted by the newborn is an excellent depository for drugs to which the fetus has been exposed. Correct diagnosis of drug use during pregnancy allows the child to receive specialized treatment and care, which will aid in learning behavioral development. Meconium analysis is gaining significant credibility as an alternative or an additional sample to neonatal or maternal urine, because meconium provides a longer history of drug use than urine and drug concentrations are higher. Therefore, number of false negative results is decreased. Meconium analysis is a relatively new scientific development. Reported analytical procedures and techniques for drugs and metabolites in meconium are predominantly cocaine-related, although other compounds have been studied. Meconium, a complex matrix, requires pre-treatment and the extraction of drugs using organic solvents and solid-phases is discussed. Preliminary drug screening using predominantly immunoassays and quantitative confirmatory analytical chromatographic methods, are reviewed. Drugs of abuse described include cocaine, amphetamines, phencyclidine, marijuana, opiates, nicotine, benzodiazepines and barbiturates.

  14. Syntactic Devices of Emphasis in Contemporary French.

    ERIC Educational Resources Information Center

    Hollerbach, Wolf

    A device of emphasis in French syntax is defined as a construction of syntactic paraphrase whose function is to make certain parts of a sentence stand out for purposes of contrast, clarification, differentiation, or because a given element is considered important. These devices exist in French because of the lack of a phonemic stress system, and…

  15. Emphasis upon Anthropo-Geography in Schools.

    ERIC Educational Resources Information Center

    Semple, Ellen Churchill

    1990-01-01

    Reprints a 1904 article from the "Journal of Geography" exploring geography's teaching focus. Argued for unchanged emphasis on the land and its people but advocated a deeper geographical interpretation of history. Contended that teaching should pay attention to scientific interpretation, and that children should discover a self-constructed…

  16. Acoustic Emphasis in Four Year Olds

    ERIC Educational Resources Information Center

    Wonnacott, Elizabeth; Watson, Duane G.

    2008-01-01

    Acoustic emphasis may convey a range of subtle discourse distinctions, yet little is known about how this complex ability develops in children. This paper presents a first investigation of the factors which influence the production of acoustic prominence in young children's spontaneous speech. In a production experiment, SVO sentences were…

  17. Project International Emphasis Interim Report, July 1991.

    ERIC Educational Resources Information Center

    Blois, Beverly, Ed.; Williams, Barbara

    Project International Emphasis (PIE), a curriculum development effort involving all 24 colleges in the Virginia Community College System (VCCS), focuses on the infusion of globally oriented components across the academic curriculum and in related career development programs. Activities undertaken during the project's first year included an annual…

  18. Incest and Child Sexual Abuse

    PubMed Central

    Collins, James L.; Hamlin, Willie T.; Minor, Marie A.; Knasel, Ann Lowe

    1982-01-01

    Child sexual abuse was examined nationally and in the Washington, DC and Howard University Hospital area. In an attempt to describe this widespread problem, two case histories are presented which reflect some of the typical characteristics of child sexual abuse cases seen at Howard University Hospital. Pertinent literature is reviewed citing the prevalence rates and the personality and environmental factors which may contribute to the sexual abuse of children in this country. Finally, the role of the physician in identifying and treating the physical and emotional effects of child abuse are discussed. PMID:7120485

  19. Incest and child sexual abuse.

    PubMed

    Collins, J L; Hamlin, W T; Minor, M A; Knasel, A L

    1982-06-01

    Child sexual abuse was examined nationally and in the Washington, DC and Howard University Hospital area. In an attempt to describe this widespread problem, two case histories are presented which reflect some of the typical characteristics of child sexual abuse cases seen at Howard University Hospital. Pertinent literature is reviewed citing the prevalence rates and the personality and environmental factors which may contribute to the sexual abuse of children in this country. Finally, the role of the physician in identifying and treating the physical and emotional effects of child abuse are discussed.

  20. Diagnostic imaging of child abuse

    SciTech Connect

    Kleinman, P.K.

    1987-01-01

    This book provides a description for all the known radiological alterations occurring in child abuse. This allows for precise interpretation of findings by radiologists. It also helps eliminate the confusion among both clinicians and non-medical personnel involved in the diagnosis, management, and legal issues related to child abuse. CONTENTS: Introduction; Skeletal trauma: general considerations; Extremity trauma; Bony thoracic trauma; Spinal trauma; Dating fractures; Visceral trauma; Head trauma; Miscellaneous forms of abuse and neglect; The postmortem examination; Differential diagnosis of child abuse; Legal considerations; Psychosocial considerations; Technical considerations and dosimetry.