NASA Technical Reports Server (NTRS)
Macfarlane, J. J.
1992-01-01
We investigate the convergence properties of Lambda-acceleration methods for non-LTE radiative transfer problems in planar and spherical geometry. Matrix elements of the 'exact' A-operator are used to accelerate convergence to a solution in which both the radiative transfer and atomic rate equations are simultaneously satisfied. Convergence properties of two-level and multilevel atomic systems are investigated for methods using: (1) the complete Lambda-operator, and (2) the diagonal of the Lambda-operator. We find that the convergence properties for the method utilizing the complete Lambda-operator are significantly better than those of the diagonal Lambda-operator method, often reducing the number of iterations needed for convergence by a factor of between two and seven. However, the overall computational time required for large scale calculations - that is, those with many atomic levels and spatial zones - is typically a factor of a few larger for the complete Lambda-operator method, suggesting that the approach should be best applied to problems in which convergence is especially difficult.
NASA Technical Reports Server (NTRS)
Rybicki, G. B.; Hummer, D. G.
1991-01-01
A method is presented for solving multilevel transfer problems when nonoverlapping lines and background continuum are present and active continuum transfer is absent. An approximate lambda operator is employed to derive linear, 'preconditioned', statistical-equilibrium equations. A method is described for finding the diagonal elements of the 'true' numerical lambda operator, and therefore for obtaining the coefficients of the equations. Iterations of the preconditioned equations, in conjunction with the transfer equation's formal solution, are used to solve linear equations. Some multilevel problems are considered, including an eleven-level neutral helium atom. Diagonal and tridiagonal approximate lambda operators are utilized in the problems to examine the convergence properties of the method, and it is found to be effective for the line transfer problems.
NASA Astrophysics Data System (ADS)
Milić, Ivan; Atanacković, Olga
2014-10-01
State-of-the-art methods in multidimensional NLTE radiative transfer are based on the use of local approximate lambda operator within either Jacobi or Gauss-Seidel iterative schemes. Here we propose another approach to the solution of 2D NLTE RT problems, Forth-and-Back Implicit Lambda Iteration (FBILI), developed earlier for 1D geometry. In order to present the method and examine its convergence properties we use the well-known instance of the two-level atom line formation with complete frequency redistribution. In the formal solution of the RT equation we employ short characteristics with two-point algorithm. Using an implicit representation of the source function in the computation of the specific intensities, we compute and store the coefficients of the linear relations J=a+bS between the mean intensity J and the corresponding source function S. The use of iteration factors in the ‘local’ coefficients of these implicit relations in two ‘inward’ sweeps of 2D grid, along with the update of the source function in other two ‘outward’ sweeps leads to four times faster solution than the Jacobi’s one. Moreover, the update made in all four consecutive sweeps of the grid leads to an acceleration by a factor of 6-7 compared to the Jacobi iterative scheme.
Two-dimensional molecular line transfer for a cometary coma
NASA Astrophysics Data System (ADS)
Szutowicz, S.
2017-09-01
In the proposed axisymmetric model of the cometary coma the gas density profile is described by an angular density function. Three methods for treating two-dimensional radiative transfer are compared: the Large Velocity Gradient (LVG) (the Sobolev method), Accelerated Lambda Iteration (ALI) and accelerated Monte Carlo (MC).
NASA Technical Reports Server (NTRS)
Kutepov, A. A.; Feofilov, A. G.; Manuilova, R. O.; Yankovsky, V. A.; Rezac, L.; Pesnell, W. D.; Goldberg, R. A.
2008-01-01
The Accelerated Lambda Iteration (ALI) technique was developed in stellar astrophysics at the beginning of 1990s for solving the non-LTE radiative transfer problem in atomic lines and multiplets in stellar atmospheres. It was later successfully applied to modeling the non-LTE emissions and radiative cooling/heating in the vibrational-rotational bands of molecules in planetary atmospheres. Similar to the standard lambda iterations ALI operates with the matrices of minimal dimension. However, it provides higher convergence rate and stability due to removing from the iterating process the photons trapped in the optically thick line cores. In the current ALI-ARMS (ALI for Atmospheric Radiation and Molecular Spectra) code version additional acceleration of calculations is provided by utilizing the opacity distribution function (ODF) approach and "decoupling". The former allows replacing the band branches by single lines of special shape, whereas the latter treats non-linearity caused by strong near-resonant vibration-vibrational level coupling without additional linearizing the statistical equilibrium equations. Latest code application for the non-LTE diagnostics of the molecular band emissions of Earth's and Martian atmospheres as well as for the non-LTE IR cooling/heating calculations are discussed.
Fast multilevel radiative transfer
NASA Astrophysics Data System (ADS)
Paletou, Frédéric; Léger, Ludovick
2007-01-01
The vast majority of recent advances in the field of numerical radiative transfer relies on approximate operator methods better known in astrophysics as Accelerated Lambda-Iteration (ALI). A superior class of iterative schemes, in term of rates of convergence, such as Gauss-Seidel and Successive Overrelaxation methods were therefore quite naturally introduced in the field of radiative transfer by Trujillo Bueno & Fabiani Bendicho (1995); it was thoroughly described for the non-LTE two-level atom case. We describe hereafter in details how such methods can be generalized when dealing with non-LTE unpolarised radiation transfer with multilevel atomic models, in monodimensional geometry.
FBILI method for multi-level line transfer
NASA Astrophysics Data System (ADS)
Kuzmanovska, O.; Atanacković, O.; Faurobert, M.
2017-07-01
Efficient non-LTE multilevel radiative transfer calculations are needed for a proper interpretation of astrophysical spectra. In particular, realistic simulations of time-dependent processes or multi-dimensional phenomena require that the iterative method used to solve such non-linear and non-local problem is as fast as possible. There are several multilevel codes based on efficient iterative schemes that provide a very high convergence rate, especially when combined with mathematical acceleration techniques. The Forth-and-Back Implicit Lambda Iteration (FBILI) developed by Atanacković-Vukmanović et al. [1] is a Gauss-Seidel-type iterative scheme that is characterized by a very high convergence rate without the need of complementing it with additional acceleration techniques. In this paper we make the implementation of the FBILI method to the multilevel atom line transfer in 1D more explicit. We also consider some of its variants and investigate their convergence properties by solving the benchmark problem of CaII line formation in the solar atmosphere. Finally, we compare our solutions with results obtained with the well known code MULTI.
TMAP: Tübingen NLTE Model-Atmosphere Package
NASA Astrophysics Data System (ADS)
Werner, Klaus; Dreizler, Stefan; Rauch, Thomas
2012-12-01
The Tübingen NLTE Model-Atmosphere Package (TMAP) is a tool to calculate stellar atmospheres in spherical or plane-parallel geometry in hydrostatic and radiative equilibrium allowing departures from local thermodynamic equilibrium (LTE) for the population of atomic levels. It is based on the Accelerated Lambda Iteration (ALI) method and is able to account for line blanketing by metals. All elements from hydrogen to nickel may be included in the calculation with model atoms which are tailored for the aims of the user.
NASA Technical Reports Server (NTRS)
Kutepov, A. A.; Kunze, D.; Hummer, D. G.; Rybicki, G. B.
1991-01-01
An iterative method based on the use of approximate transfer operators, which was designed initially to solve multilevel NLTE line formation problems in stellar atmospheres, is adapted and applied to the solution of the NLTE molecular band radiative transfer in planetary atmospheres. The matrices to be constructed and inverted are much smaller than those used in the traditional Curtis matrix technique, which makes possible the treatment of more realistic problems using relatively small computers. This technique converges much more rapidly than straightforward iteration between the transfer equation and the equations of statistical equilibrium. A test application of this new technique to the solution of NLTE radiative transfer problems for optically thick and thin bands (the 4.3 micron CO2 band in the Venusian atmosphere and the 4.7 and 2.3 micron CO bands in the earth's atmosphere) is described.
NASA Technical Reports Server (NTRS)
Hubeny, I.; Lanz, T.
1995-01-01
A new munerical method for computing non-Local Thermodynamic Equilibrium (non-LTE) model stellar atmospheres is presented. The method, called the hybird complete linearization/accelerated lambda iretation (CL/ALI) method, combines advantages of both its constituents. Its rate of convergence is virtually as high as for the standard CL method, while the computer time per iteration is almost as low as for the standard ALI method. The method is formulated as the standard complete lineariation, the only difference being that the radiation intensity at selected frequency points is not explicity linearized; instead, it is treated by means of the ALI approach. The scheme offers a wide spectrum of options, ranging from the full CL to the full ALI method. We deonstrate that the method works optimally if the majority of frequency points are treated in the ALI mode, while the radiation intensity at a few (typically two to 30) frequency points is explicity linearized. We show how this method can be applied to calculate metal line-blanketed non-LTE model atmospheres, by using the idea of 'superlevels' and 'superlines' introduced originally by Anderson (1989). We calculate several illustrative models taking into accont several tens of thosands of lines of Fe III to Fe IV and show that the hybrid CL/ALI method provides a robust method for calculating non-LTE line-blanketed model atmospheres for a wide range of stellar parameters. The results for individual stellar types will be presented in subsequent papers in this series.
Solution of the symmetric eigenproblem AX=lambda BX by delayed division
NASA Technical Reports Server (NTRS)
Thurston, G. A.; Bains, N. J. C.
1986-01-01
Delayed division is an iterative method for solving the linear eigenvalue problem AX = lambda BX for a limited number of small eigenvalues and their corresponding eigenvectors. The distinctive feature of the method is the reduction of the problem to an approximate triangular form by systematically dropping quadratic terms in the eigenvalue lambda. The report describes the pivoting strategy in the reduction and the method for preserving symmetry in submatrices at each reduction step. Along with the approximate triangular reduction, the report extends some techniques used in the method of inverse subspace iteration. Examples are included for problems of varying complexity.
Scattering from very rough layers under the geometric optics approximation: further investigation.
Pinel, Nicolas; Bourlier, Christophe
2008-06-01
Scattering from very rough homogeneous layers is studied in the high-frequency limit (under the geometric optics approximation) by taking the shadowing effect into account. To do so, the iterated Kirchhoff approximation, recently developed by Pinel et al. [Waves Random Complex Media17, 283 (2007)] and reduced to the geometric optics approximation, is used and investigated in more detail. The contributions from the higher orders of scattering inside the rough layer are calculated under the iterated Kirchhoff approximation. The method can be applied to rough layers of either very rough or perfectly flat lower interfaces, separating either lossless or lossy media. The results are compared with the PILE (propagation-inside-layer expansion) method, recently developed by Déchamps et al. [J. Opt. Soc. Am. A23, 359 (2006)], and accelerated by the forward-backward method with spectral acceleration. They highlight that there is very good agreement between the developed method and the reference numerical method for all scattering orders and that the method can be applied to root-mean-square (RMS) heights at least down to 0.25lambda.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Leros, Nicolas
2001-06-01
The HyperCP(EB71) experiment, performed at the Fermi National Accelerator Laboratory in the United States, provides a primary search for direct OP violation in the decays ofmore » $$\\Xi^-/\\bar{\\Xi}^+$$ and $$\\Lambda/ \\bar{\\Lambda}$$ hyperons....« less
NASA Astrophysics Data System (ADS)
Pauldrach, A. W. A.; Hoffmann, T. L.; Hultzsch, P. J. N.
2014-09-01
Context. In type Ia supernova (SN Ia) envelopes a huge number of lines of different elements overlap within their thermal Doppler widths, and this problem is exacerbated by the circumstance that up to 20% of these lines can have a line optical depth higher than 1. The stagnation of the lambda iteration in such optically thick cases is one of the fundamental physical problems inherent in the iterative solution of the non-LTE problem, and the failure of a lambda iteration to converge is a point of crucial importance whose physical significance must be understood completely. Aims: We discuss a general problem related to radiative transfer under the physical conditions of supernova ejecta that involves a failure of the usual non-LTE iteration scheme to converge when multiple strong opacities belonging to different physical transitions come together, similar to the well-known situation where convergence is impaired even when only a single process attains high optical depths. The convergence problem is independent of the chosen frequency and depth grid spacing, independent of whether the radiative transfer is solved in the comoving or observer's frame, and independent of whether a common complete-linearization scheme or a conventional accelerated lambda iteration (ALI) is used. The problem appears when all millions of line transitions required for a realistic description of SN Ia envelopes are treated in the frame of a comprehensive non-LTE model. The only solution to this problem is a complete-linearization approach that considers all ions of all elements simultaneously, or an adequate generalization of the established ALI technique that accounts for the mutual interaction of the strong spectral lines of different elements and which thereby unfreezes the "stuck" state of the iteration. Methods: The physics of the atmospheres of SN Ia are strongly affected by the high-velocity expansion of the ejecta, which dominates the formation of the spectra at all wavelength ranges. Thus, hydrodynamic explosion models and realistic model atmospheres that take into account the strong deviation from local thermodynamic equilibrium (LTE) are necessary for the synthesis and analysis of the spectra. In this regard one of the biggest challenges we have found in modeling the radiative transfer in SN Ia is the fact that the radiative energy in the UV has to be transferred only via spectral lines into the optical regime to be able to leave the ejecta. However, convergence of the model toward a state where this is possible is impaired when using the standard procedures. We report on improvements in our approach of computing synthetic spectra for SN Ia with respect to (i) an improved and sophisticated treatment of many thousands of strong lines that interact intricately with the "pseudo-continuum" formed entirely by Doppler-shifted spectral lines; (ii) an improved and expanded atomic database; and (iii) the inclusion of energy deposition within the ejecta arising from the radioactive decay of mostly 56Ni and 56Co. Results: We show that an ALI procedure we have developed for the mutual interaction of strong spectral lines appearing in the atmospheres of SNe Ia solves the long-standing problem of transferring the radiative energy from the UV into the optical regime. Our new method thus constitutes a foundation for more refined models, such as those including energy deposition. In this regard we furthermore show synthetic spectra obtained with various methods adopted for the released energy and compare them with observations. We discuss in detail applications of the diagnostic technique by example of a standard type Ia supernova, where the comparison of calculated and observed spectra revealed that in the early phases the consideration of the energy deposition within the spectrum-forming regions of the ejecta does not qualitatively alter the shape of the emergent spectra. Conclusions: The results of our investigation lead to an improved understanding of how the shape of the spectrum changes radically as function of depth in the ejecta, and show how different emergent spectra are formed as a result of the particular physical properties of SNe Ia ejecta and the resulting peculiarities in the radiative transfer. This knowledge provides an important insight into the process of extracting information from observed SN Ia spectra, since these spectra are a complex product of numerous unobservable SN Ia spectral features, which are thus analyzed in parallel to the observable SN Ia spectral features.
NASA Astrophysics Data System (ADS)
Sampoorna, M.; Trujillo Bueno, J.
2010-04-01
The linearly polarized solar limb spectrum that is produced by scattering processes contains a wealth of information on the physical conditions and magnetic fields of the solar outer atmosphere, but the modeling of many of its strongest spectral lines requires solving an involved non-local thermodynamic equilibrium radiative transfer problem accounting for partial redistribution (PRD) effects. Fast radiative transfer methods for the numerical solution of PRD problems are also needed for a proper treatment of hydrogen lines when aiming at realistic time-dependent magnetohydrodynamic simulations of the solar chromosphere. Here we show how the two-level atom PRD problem with and without polarization can be solved accurately and efficiently via the application of highly convergent iterative schemes based on the Gauss-Seidel and successive overrelaxation (SOR) radiative transfer methods that had been previously developed for the complete redistribution case. Of particular interest is the Symmetric SOR method, which allows us to reach the fully converged solution with an order of magnitude of improvement in the total computational time with respect to the Jacobi-based local accelerated lambda iteration method.
Lambda-universe in scalar-tensor gravity
NASA Astrophysics Data System (ADS)
Berman, Marcelo Samuel
2009-09-01
We present a lambda-Universe, in scalar-tensor gravity, reviewing Berman and Trevisan’s inflationary case (Berman and Trevisan in Int. J. Theor. Phys., 2009) and then we find a solution for an accelerating power-law scale-factor. The negativity of cosmic pressure implies acceleration of the expansion, even with Λ<0. The cosmological term, and the coupling “constant”, are in fact, time-varying.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dul, F.A.; Arczewski, K.
1994-03-01
Although it has been stated that [open quotes]an attempt to solve (very large problems) by subspace iterations seems futile[close quotes], we will show that the statement is not true, especially for extremely large eigenproblems. In this paper a new two-phase subspace iteration/Rayleigh quotient/conjugate gradient method for generalized, large, symmetric eigenproblems Ax = [lambda]Bx is presented. It has the ability of solving extremely large eigenproblems, N = 216,000, for example, and finding a large number of leftmost or rightmost eigenpairs, up to 1000 or more. Multiple eigenpairs, even those with multiplicity 100, can be easily found. The use of the proposedmore » method for solving the big full eigenproblems (N [approximately] 10[sup 3]), as well as for large weakly non-symmetric eigenproblems, have been considered also. The proposed method is fully iterative; thus the factorization of matrices ins avoided. The key idea consists in joining two methods: subspace and Rayleigh quotient iterations. The systems of indefinite and almost singular linear equations (a - [sigma]B)x = By are solved by various iterative conjugate gradient method can be used without danger of breaking down due to its property that may be called [open quotes]self-correction towards the eigenvector,[close quotes] discovered recently by us. The use of various preconditioners (SSOR and IC) has also been considered. The main features of the proposed method have been analyzed in detail. Comparisons with other methods, such as, accelerated subspace iteration, Lanczos, Davidson, TLIME, TRACMN, and SRQMCG, are presented. The results of numerical tests for various physical problems (acoustic, vibrations of structures, quantum chemistry) are presented as well. 40 refs., 12 figs., 2 tabs.« less
Iterative retrieval of surface emissivity and temperature for a hyperspectral sensor
DOE Office of Scientific and Technical Information (OSTI.GOV)
Borel, C.C.
1997-11-01
The central problem of temperature-emissivity separation is that we obtain N spectral measurements of radiance and need to find N + 1 unknowns (N emissivities and one temperature). To solve this problem in the presence of the atmosphere we need to find even more unknowns: N spectral transmissions {tau}{sub atmo}({lambda}) up-welling path radiances L{sub path}{up_arrow}({lambda}) and N down-welling path radiances L{sub path}{down_arrow}({lambda}). Fortunately there are radiative transfer codes such as MODTRAN 3 and FASCODE available to get good estimates of {tau}{sub atmo}({lambda}), L{sub path}{up_arrow}({lambda}) and L{sub path}{down_arrow}({lambda}) in the order of a few percent. With the growing use of hyperspectralmore » imagers, e.g. AVIRIS in the visible and short-wave infrared there is hope of using such instruments in the mid-wave and thermal IR (TIR) some day. We believe that this will enable us to get around using the present temperature - emissivity separation (TES) algorithms using methods which take advantage of the many channels available in hyperspectral imagers. The first idea we had is to take advantage of the simple fact that a typical surface emissivity spectrum is rather smooth compared to spectral features introduced by the atmosphere. Thus iterative solution techniques can be devised which retrieve emissivity spectra {epsilon} based on spectral smoothness. To make the emissivities realistic, atmospheric parameters are varied using approximations, look-up tables derived from a radiative transfer code and spectral libraries. By varying the surface temperature over a small range a series of emissivity spectra are calculated. The one with the smoothest characteristic is chosen. The algorithm was tested on synthetic data using MODTRAN and the Salisbury emissivity database.« less
Narrow-line region kinematics in Seyfert nuclei
NASA Astrophysics Data System (ADS)
Moore, David J.
1994-01-01
We present results of a study of narrow-line region (NLR) kinematics in Seyfert nuclei. This study has involved extensive modeling which includes collimated emission, radially dependent rotation and turbulence, explicit photoionization calculations, realistic treatments of both internal and external obscuration, and allows for gradients in the electron density and the radial velocity of clouds throughout the NLR. Line profiles of (O II) lambda 3727, (Ne III) lambda 3869, (O III) lambda 5007, (Fe VII) lambda 6087, (Fe X) lambda 6374, (O I) lambda 6300, H alpha lambda 6563, and (S II) lambda 6731 are calculated for a wide range of physical conditions throughout the NLR. The model profiles are compared with line profiles derived from data taken with the Mount Palomar 5 m Hale Telescope as well as from profiles taken from the literature. The scenario in agreement with the largest of observational considerations consists of clouds which are accelerating outward with v varies as square root of r (i.e., constant force) and ne varies as 1/r2. The cloud start out at the inner NLR radium with ne approximately equal to 106/cu cm and with a very large column density (1023 - 10(exp 24/sq cm). These clouds are uniformly accelerated from a few tens of km/sec to approximately less than 1,000 km/sec. When the clouds reached the outer NLR radius, they have ne approximately greater than 102/cu cm and a column density of 1021-1022/sq cm. The clouds maintain an ionization parameter of about 0.3 throughout the NLR.
On the use of transition matrix methods with extended ensembles.
Escobedo, Fernando A; Abreu, Charlles R A
2006-03-14
Different extended ensemble schemes for non-Boltzmann sampling (NBS) of a selected reaction coordinate lambda were formulated so that they employ (i) "variable" sampling window schemes (that include the "successive umbrella sampling" method) to comprehensibly explore the lambda domain and (ii) transition matrix methods to iteratively obtain the underlying free-energy eta landscape (or "importance" weights) associated with lambda. The connection between "acceptance ratio" and transition matrix methods was first established to form the basis of the approach for estimating eta(lambda). The validity and performance of the different NBS schemes were then assessed using as lambda coordinate the configurational energy of the Lennard-Jones fluid. For the cases studied, it was found that the convergence rate in the estimation of eta is little affected by the use of data from high-order transitions, while it is noticeably improved by the use of a broader window of sampling in the variable window methods. Finally, it is shown how an "elastic" window of sampling can be used to effectively enact (nonuniform) preferential sampling over the lambda domain, and how to stitch the weights from separate one-dimensional NBS runs to produce a eta surface over a two-dimensional domain.
Time-resolved diffusion tomographic imaging in highly scattering turbid media
NASA Technical Reports Server (NTRS)
Alfano, Robert R. (Inventor); Cai, Wei (Inventor); Liu, Feng (Inventor); Lax, Melvin (Inventor); Das, Bidyut B. (Inventor)
1998-01-01
A method for imaging objects in highly scattering turbid media. According to one embodiment of the invention, the method involves using a plurality of intersecting source/detectors sets and time-resolving equipment to generate a plurality of time-resolved intensity curves for the diffusive component of light emergent from the medium. For each of the curves, the intensities at a plurality of times are then inputted into the following inverse reconstruction algorithm to form an image of the medium: X.sup.(k+1).spsp.T =?Y.sup.T W+X.sup.(k).spsp.T .LAMBDA.!?W.sup.T W+.LAMBDA.!.sup.-1 wherein W is a matrix relating output at detector position r.sub.d, at time t, to source at position r.sub.s, .LAMBDA. is a regularization matrix, chosen for convenience to be diagonal, but selected in a way related to the ratio of the noise,
Gaussian beam and physical optics iteration technique for wideband beam waveguide feed design
NASA Technical Reports Server (NTRS)
Veruttipong, W.; Chen, J. C.; Bathker, D. A.
1991-01-01
The Gaussian beam technique has become increasingly popular for wideband beam waveguide (BWG) design. However, it is observed that the Gaussian solution is less accurate for smaller mirrors (approximately less than 30 lambda in diameter). Therefore, a high-performance wideband BWG design cannot be achieved by using the Gaussian beam technique alone. This article demonstrates a new design approach by iterating Gaussian beam and BWG parameters simultaneously at various frequencies to obtain a wideband BWG. The result is further improved by comparing it with physical optics results and repeating the iteration.
Optimization and application of influence function in abrasive jet polishing.
Li, Zhaoze; Li, Shengyi; Dai, Yifan; Peng, Xiaoqiang
2010-05-20
We analyze the material removal mechanism of abrasive jet polishing (AJP) technology, based on the fluid impact dynamics theory. Combined with the computational fluid dynamics simulation and process experiments, influence functions at different impingement angles are obtained, which are not of a regular Gaussian shape and are unfit for the corrective figuring of optics. The influence function is then optimized to obtain an ideal Gaussian shape by rotating the oblique nozzle, and its stability is validated through a line scanning experiment. The fluctuation of the influence function can be controlled within +/-5%. Based on this, we build a computed numerically controlled experimental system for AJP, and one flat BK7 optical glass with a diameter of 20mm is polished. After two iterations of polishing, the peak-to-valley value decreases from 1.43lambda (lambda=632.8nm in this paper) to 0.294lambda, and the rms value decreases from 0.195lambda to 0.029lambda. The roughness of this polished surface is within 2nm. The experimental result indicates that the optimized influence function is suitable for precision optics figuring and polishing.
Coupled-cavity drift-tube linac
Billen, James H.
1996-01-01
A coupled-cavity drift-tube linac (CCDTL) combines features of the Alvarez drift-tube linac (DTL) and the .pi.-mode coupled-cavity linac (CCL). In one embodiment, each accelerating cavity is a two-cell, 0-mode DTL. The center-to-center distance between accelerating gaps is .beta..lambda., where .lambda. is the free-space wavelength of the resonant mode. Adjacent accelerating cavities have oppositely directed electric fields, alternating in phase by 180 degrees. The chain of cavities operates in a .pi./2 structure mode so the coupling cavities are nominally unexcited. The CCDTL configuration provides an rf structure with high shunt impedance for intermediate velocity charged particles, i.e., particles with energies in the 20-200 MeV range.
Coupled-cavity drift-tube linac
Billen, J.H.
1996-11-26
A coupled-cavity drift-tube linac (CCDTL) combines features of the Alvarez drift-tube linac (DTL) and the {pi}-mode coupled-cavity linac (CCL). In one embodiment, each accelerating cavity is a two-cell, 0-mode DTL. The center-to-center distance between accelerating gaps is {beta}{lambda}, where {lambda} is the free-space wavelength of the resonant mode. Adjacent accelerating cavities have oppositely directed electric fields, alternating in phase by 180 degrees. The chain of cavities operates in a {pi}/2 structure mode so the coupling cavities are nominally unexcited. The CCDTL configuration provides an rf structure with high shunt impedance for intermediate velocity charged particles, i.e., particles with energies in the 20-200 MeV range. 5 figs.
AIR-MRF: Accelerated iterative reconstruction for magnetic resonance fingerprinting.
Cline, Christopher C; Chen, Xiao; Mailhe, Boris; Wang, Qiu; Pfeuffer, Josef; Nittka, Mathias; Griswold, Mark A; Speier, Peter; Nadar, Mariappan S
2017-09-01
Existing approaches for reconstruction of multiparametric maps with magnetic resonance fingerprinting (MRF) are currently limited by their estimation accuracy and reconstruction time. We aimed to address these issues with a novel combination of iterative reconstruction, fingerprint compression, additional regularization, and accelerated dictionary search methods. The pipeline described here, accelerated iterative reconstruction for magnetic resonance fingerprinting (AIR-MRF), was evaluated with simulations as well as phantom and in vivo scans. We found that the AIR-MRF pipeline provided reduced parameter estimation errors compared to non-iterative and other iterative methods, particularly at shorter sequence lengths. Accelerated dictionary search methods incorporated into the iterative pipeline reduced the reconstruction time at little cost of quality. Copyright © 2017 Elsevier Inc. All rights reserved.
Spectroscopy of the neutron-rich hypernucleus He Λ 7 from electron scattering
Gogami, T.; Chen, C.; Kawama, D.; ...
2016-08-12
Here, the missing mass spectroscopy of themore » $$^{7}_{\\Lambda}$$He hypernucleus was performed, using the $$^{7}$$Li$$(e,e^{\\prime}K^{+})^{7}_{\\Lambda}$$He reaction at the Thomas Jefferson National Accelerator Facility Hall C. The $$\\Lambda$$ binding energy of the ground state (1/2$$^{+}$$) was determined with a smaller error than that of the previous measurement, being $$B_{\\Lambda}$$ = 5.55 $$\\pm$$ 0.10(stat.) $$\\pm$$ 0.11(sys.) MeV. The experiment also provided new insight into charge symmetry breaking in p-shell hypernuclear systems. Finally, a peak at $$B_{\\Lambda}$$ = 3.65 $$\\pm$$ 0.20(stat.) $$\\pm$$ 0.11(sys.) MeV was observed and assigned as a mixture of 3/2$$^{+}$$ and 5/2$$^{+}$$ states, confirming the "gluelike" behavior of $$\\Lambda$$, which makes an unstable state in $$^{6}$$He stable against neutron emission.« less
{lambda} elements for one-dimensional singular problems with known strength of singularity
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wong, K.K.; Surana, K.S.
1996-10-01
This paper presents a new and general procedure for designing special elements called {lambda} elements for one dimensional singular problems where the strength of the singularity is know. The {lambda} elements presented here are of type C{sup 0}. These elements also provide inter-element C{sup 0} continuity with p-version elements. The {lambda} elements do not require a precise knowledge of the extent of singular zone, i.e., their use may be extended beyond the singular zone. When {lambda} elements are used at the singularity, a singular problem behaves like a smooth problem thereby eliminating the need for h, p-adaptive processes all together.more » One dimensional steady state radial flow of an upper convected Maxwell fluid is considered as a sample problem. Least squares approach (or least squares finite element formulation: LSFEF) is used to construct the integral form (error functional I) from the differential equations. Numerical results presented for radially inward flow with inner radius r{sub i} = 0.1, 0.01, 0.001, 0.0001, 0.00001, and Deborah number of 2 (De = 2) demonstrate the accuracy, faster convergence of the iterative solution procedure, faster convergence rate of the error functional and mesh independent characteristics of the {lambda} elements regardless of the severity of the singularity.« less
NASA Astrophysics Data System (ADS)
Zulick, Calvin Andrew
The development of short pulse high power lasers has led to interest in laser based particle accelerators. Laser produced plasmas have been shown to support quasi-static TeV/m acceleration gradients which are more than four orders of magnitude stronger than conventional accelerators. These high gradients have the potential to allow compact particle accelerators for active interrogation of nuclear material. In order to better understand this application, several experiments have been conducted at the HERCULES and Lambda Cubed lasers as the Center for Ultrafast Optical Science at the University of Michigan. Electron acceleration and bremsstrahlung generation were studied on the Lambda Cubed laser. The scaling of the intensity, angular, and material dependence of bremsstrahlung radiation from an intense (I > 10 18 W/cm2 ) laser-solid interaction has been characterized at energies between 100 keV and 1 MeV. These were the first high resolution (lambda / d lambda > 100) measurements of bremsstrahlung photons from a relativistic laser plasma interaction. The electron populations and bremsstrahlung temperatures were modeled in the particle-in-cell code OSIRIS and the Monte Carlo code MCNPX and were in good agreement with the experimental results. Proton acceleration was studied on the HERCULES laser. The effect of three dimensional perturbations of electron sheaths on proton acceleration was investigated through the use of foil, grid, and wire targets. Hot electron density, as measured with an imaging Cu Kalpha crystal, increased as the target surface area was reduced and was correlated to an increase in the temperature of the accelerated proton beam. Additionally, experiments at the HERCULES laser facility have produced directional neutron beams with energies up to 16.8 (+/-0.3) MeV using (d,n) and (p,n) reactions. Efficient (d,n) reactions required the selective acceleration of deuterons through the introduction of a deuterated plastic or cryogenically frozen D2O layer on the surface of a thin film target. The measured neutron yield was up to 1.0 (+/-0.5) x 107 neutrons/sr with a flux 6.2 (+/-3.7) times higher in the forward direction than at 90 degrees . This demonstrated that femtosecond lasers are capable of providing a time averaged neutron flux equivalent to commercial DD generators with the advantage of a directional beam with picosecond bunch duration.
Jiang, Wei; Roux, Benoît
2010-07-01
Free Energy Perturbation with Replica Exchange Molecular Dynamics (FEP/REMD) offers a powerful strategy to improve the convergence of free energy computations. In particular, it has been shown previously that a FEP/REMD scheme allowing random moves within an extended replica ensemble of thermodynamic coupling parameters "lambda" can improve the statistical convergence in calculations of absolute binding free energy of ligands to proteins [J. Chem. Theory Comput. 2009, 5, 2583]. In the present study, FEP/REMD is extended and combined with an accelerated MD simulations method based on Hamiltonian replica-exchange MD (H-REMD) to overcome the additional problems arising from the existence of kinetically trapped conformations within the protein receptor. In the combined strategy, each system with a given thermodynamic coupling factor lambda in the extended ensemble is further coupled with a set of replicas evolving on a biased energy surface with boosting potentials used to accelerate the inter-conversion among different rotameric states of the side chains in the neighborhood of the binding site. Exchanges are allowed to occur alternatively along the axes corresponding to the thermodynamic coupling parameter lambda and the boosting potential, in an extended dual array of coupled lambda- and H-REMD simulations. The method is implemented on the basis of new extensions to the REPDSTR module of the biomolecular simulation program CHARMM. As an illustrative example, the absolute binding free energy of p-xylene to the nonpolar cavity of the L99A mutant of T4 lysozyme was calculated. The tests demonstrate that the dual lambda-REMD and H-REMD simulation scheme greatly accelerates the configurational sampling of the rotameric states of the side chains around the binding pocket, thereby improving the convergence of the FEP computations.
Yan, X Q; Lin, C; Sheng, Z M; Guo, Z Y; Liu, B C; Lu, Y R; Fang, J X; Chen, J E
2008-04-04
A new ion acceleration method, namely, phase-stable acceleration, using circularly-polarized laser pulses is proposed. When the initial target density n(0) and thickness D satisfy a(L) approximately (n(0)/n(c))D/lambda(L) and D>l(s) with a(L), lambda(L), l(s), and n(c) the normalized laser amplitude, the laser wavelength in vacuum, the plasma skin depth, and the critical density of the incident laser pulse, respectively, a quasiequilibrium for the electrons is established by the light pressure and the space charge electrostatic field at the interacting front of the laser pulse. The ions within the skin depth of the laser pulse are synchronously accelerated and bunched by the electrostatic field, and thereby a high-intensity monoenergetic proton beam can be generated. The proton dynamics is investigated analytically and the results are verified by one- and two-dimensional particle-in-cell simulations.
Near-Infrared (0.67-4.7 microns) Optical Constants Estimated for Montmorillonite
NASA Technical Reports Server (NTRS)
Roush, T. L.
2005-01-01
Various models of the reflectance from particulate surfaces are used for interpretation of remote sensing data of solar system objects. These models rely upon the real (n) and imaginary (k) refractive indices of the materials. Such values are limited for commonly encountered silicates at visual and near-infrared wavelengths (lambda, 0.4-5 microns). Availability of optical constants for candidate materials allows more thorough modeling of the observations obtained by Earth-based telescopes and spacecraft. Two approaches for determining the absorption coefficient (alpha=2pik/lambda) from reflectance measurements of particulates have been described; one relies upon Kubelka-Munk theory and the other Hapke theory. Both have been applied to estimate alpha and k for various materials. Neither enables determination of the wavelength dependence of n, n=f(lambda). Thus, a mechanism providing this ability is desirable. Using Hapke-theory to estimate k from reflectance measurements requires two additional quantities be known or assumed: 1) n=f(lambda) and 2) d, the sample particle diameter. Typically n is assumed constant (c) or modestly varying with lambda; referred to here as n(sub 0). Assuming n(sub 0), at each lambda an estimate of k is used to calculate the reflectance and is iteratively adjusted until the difference between the model and measured reflectance is minimized. The estimated k's (k(sub 1)) are the final results, and this concludes the typical analysis.
Spectroscopic Research of Lambda Hypdernuclei at JLab Hall C
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gogami, Toshiyuki; et. al.,
2014-03-01
A Lambda hyperon which has a strangeness can be bound in deep inside of a nucleus since a Λ does not suffer from the Pauli exclusion principle from nucleons. Thus, a Λ could be a useful tool to investigate inside of a nucleus. Since 2000, Lambda hypernuclear spectroscopic experiments by the (e,e'k) reaction have been performed at the experimental hall C in Thomas Jefferson National Accelerator Facility (JLab Hall C). An experiment, JLab E05-115 was carried out to investigate Lambda hypernuclei with a wide mass range (the mass number, A = 7, 9, 10, 12, 52). The latest analysis statusmore » of JLab E05-115 experiment is discussed in the present article.« less
Multilevel acceleration of scattering-source iterations with application to electron transport
Drumm, Clif; Fan, Wesley
2017-08-18
Acceleration/preconditioning strategies available in the SCEPTRE radiation transport code are described. A flexible transport synthetic acceleration (TSA) algorithm that uses a low-order discrete-ordinates (S N) or spherical-harmonics (P N) solve to accelerate convergence of a high-order S N source-iteration (SI) solve is described. Convergence of the low-order solves can be further accelerated by applying off-the-shelf incomplete-factorization or algebraic-multigrid methods. Also available is an algorithm that uses a generalized minimum residual (GMRES) iterative method rather than SI for convergence, using a parallel sweep-based solver to build up a Krylov subspace. TSA has been applied as a preconditioner to accelerate the convergencemore » of the GMRES iterations. The methods are applied to several problems involving electron transport and problems with artificial cross sections with large scattering ratios. These methods were compared and evaluated by considering material discontinuities and scattering anisotropy. Observed accelerations obtained are highly problem dependent, but speedup factors around 10 have been observed in typical applications.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Willert, Jeffrey; Taitano, William T.; Knoll, Dana
In this note we demonstrate that using Anderson Acceleration (AA) in place of a standard Picard iteration can not only increase the convergence rate but also make the iteration more robust for two transport applications. We also compare the convergence acceleration provided by AA to that provided by moment-based acceleration methods. Additionally, we demonstrate that those two acceleration methods can be used together in a nested fashion. We begin by describing the AA algorithm. At this point, we will describe two application problems, one from neutronics and one from plasma physics, on which we will apply AA. We provide computationalmore » results which highlight the benefits of using AA, namely that we can compute solutions using fewer function evaluations, larger time-steps, and achieve a more robust iteration.« less
An accelerated subspace iteration for eigenvector derivatives
NASA Technical Reports Server (NTRS)
Ting, Tienko
1991-01-01
An accelerated subspace iteration method for calculating eigenvector derivatives has been developed. Factors affecting the effectiveness and the reliability of the subspace iteration are identified, and effective strategies concerning these factors are presented. The method has been implemented, and the results of a demonstration problem are presented.
Anderson acceleration and application to the three-temperature energy equations
NASA Astrophysics Data System (ADS)
An, Hengbin; Jia, Xiaowei; Walker, Homer F.
2017-10-01
The Anderson acceleration method is an algorithm for accelerating the convergence of fixed-point iterations, including the Picard method. Anderson acceleration was first proposed in 1965 and, for some years, has been used successfully to accelerate the convergence of self-consistent field iterations in electronic-structure computations. Recently, the method has attracted growing attention in other application areas and among numerical analysts. Compared with a Newton-like method, an advantage of Anderson acceleration is that there is no need to form the Jacobian matrix. Thus the method is easy to implement. In this paper, an Anderson-accelerated Picard method is employed to solve the three-temperature energy equations, which are a type of strong nonlinear radiation-diffusion equations. Two strategies are used to improve the robustness of the Anderson acceleration method. One strategy is to adjust the iterates when necessary to satisfy the physical constraint. Another strategy is to monitor and, if necessary, reduce the matrix condition number of the least-squares problem in the Anderson-acceleration implementation so that numerical stability can be guaranteed. Numerical results show that the Anderson-accelerated Picard method can solve the three-temperature energy equations efficiently. Compared with the Picard method without acceleration, Anderson acceleration can reduce the number of iterations by at least half. A comparison between a Jacobian-free Newton-Krylov method, the Picard method, and the Anderson-accelerated Picard method is conducted in this paper.
Li, Haichen; Yaron, David J
2016-11-08
A least-squares commutator in the iterative subspace (LCIIS) approach is explored for accelerating self-consistent field (SCF) calculations. LCIIS is similar to direct inversion of the iterative subspace (DIIS) methods in that the next iterate of the density matrix is obtained as a linear combination of past iterates. However, whereas DIIS methods find the linear combination by minimizing a sum of error vectors, LCIIS minimizes the Frobenius norm of the commutator between the density matrix and the Fock matrix. This minimization leads to a quartic problem that can be solved iteratively through a constrained Newton's method. The relationship between LCIIS and DIIS is discussed. Numerical experiments suggest that LCIIS leads to faster convergence than other SCF convergence accelerating methods in a statistically significant sense, and in a number of cases LCIIS leads to stable SCF solutions that are not found by other methods. The computational cost involved in solving the quartic minimization problem is small compared to the typical cost of SCF iterations and the approach is easily integrated into existing codes. LCIIS can therefore serve as a powerful addition to SCF convergence accelerating methods in computational quantum chemistry packages.
Anderson Acceleration for Fixed-Point Iterations
DOE Office of Scientific and Technical Information (OSTI.GOV)
Walker, Homer F.
The purpose of this grant was to support research on acceleration methods for fixed-point iterations, with applications to computational frameworks and simulation problems that are of interest to DOE.
Charm: Cosmic history agnostic reconstruction method
NASA Astrophysics Data System (ADS)
Porqueres, Natalia; Ensslin, Torsten A.
2017-03-01
Charm (cosmic history agnostic reconstruction method) reconstructs the cosmic expansion history in the framework of Information Field Theory. The reconstruction is performed via the iterative Wiener filter from an agnostic or from an informative prior. The charm code allows one to test the compatibility of several different data sets with the LambdaCDM model in a non-parametric way.
NASA Astrophysics Data System (ADS)
Dybalski, Wojciech; Pizzo, Alessandro
2018-02-01
Let $H_{P,\\sigma}$ be the single-electron fiber Hamiltonians of the massless Nelson model at total momentum $P$ and infrared cut-off $\\sigma>0$. We establish detailed regularity properties of the corresponding $n$-particle ground state wave functions $f^n_{P,\\sigma}$ as functions of $P$ and $\\sigma$. In particular, we show that \\[ |\\partial_{P^j}f^{n}_{P,\\sigma}(k_1,\\ldots, k_n)|, \\ \\ |\\partial_{P^j} \\partial_{P^{j'}} f^{n}_{P,\\sigma}(k_1,\\ldots, k_n)| \\leq \\frac{1}{\\sqrt{n!}} \\frac{(c\\lambda_0)^n}{\\sigma^{\\delta_{\\lambda_0}}} \\prod_{i=1}^n\\frac{ \\chi_{[\\sigma,\\kappa)}(k_i)}{|k_i|^{3/2}}, \\] where $c$ is a numerical constant, $\\lambda_0\\mapsto \\delta_{\\lambda_0}$ is a positive function of the maximal admissible coupling constant which satisfies $\\lim_{\\lambda_0\\to 0}\\delta_{\\lambda_0}=0$ and $\\chi_{[\\sigma,\\kappa)}$ is the (approximate) characteristic function of the energy region between the infrared cut-off $\\sigma$ and the ultraviolet cut-off $\\kappa$. While the analysis of the first derivative is relatively straightforward, the second derivative requires a new strategy. By solving a non-commutative recurrence relation we derive a novel formula for $f^n_{P,\\sigma}$ with improved infrared properties. In this representation $\\partial_{P^{j'}}\\partial_{P^{j}}f^n_{P,\\sigma}$ is amenable to sharp estimates obtained by iterative analytic perturbation theory in part II of this series of papers. The bounds stated above are instrumental for scattering theory of two electrons in the Nelson model, as explained in part I of this series.
Dark Energy and the Cosmological Constant: A Brief Introduction
ERIC Educational Resources Information Center
Harvey, Alex
2009-01-01
The recently observed acceleration of the expansion of the universe is a topic of intense interest. The favoured causes are the "cosmological constant" or "dark energy". The former, which appears in the Einstein equations as the term [lambda]g[subscript [mu]v], provides an extremely simple, well-defined mechanism for the acceleration. However,…
Benzi, Michele; Evans, Thomas M.; Hamilton, Steven P.; ...
2017-03-05
Here, we consider hybrid deterministic-stochastic iterative algorithms for the solution of large, sparse linear systems. Starting from a convergent splitting of the coefficient matrix, we analyze various types of Monte Carlo acceleration schemes applied to the original preconditioned Richardson (stationary) iteration. We expect that these methods will have considerable potential for resiliency to faults when implemented on massively parallel machines. We also establish sufficient conditions for the convergence of the hybrid schemes, and we investigate different types of preconditioners including sparse approximate inverses. Numerical experiments on linear systems arising from the discretization of partial differential equations are presented.
NASA Technical Reports Server (NTRS)
Feofilov, Artem G.; Yankovsky, Valentine A.; Pesnell, William D.; Kutepov, Alexander A.; Goldberg, Richard A.; Mauilova, Rada O.
2007-01-01
We present the new version of the ALI-ARMS (for Accelerated Lambda Iterations for Atmospheric Radiation and Molecular Spectra) model. The model allows simultaneous self-consistent calculating the non-LTE populations of the electronic-vibrational levels of the O3 and O2 photolysis products and vibrational level populations of CO2, N2,O2, O3, H2O, CO and other molecules with detailed accounting for the variety of the electronic-vibrational, vibrational-vibrational and vibrational-translational energy exchange processes. The model was used as the reference one for modeling the O2 dayglows and infrared molecular emissions for self-consistent diagnostics of the multi-channel space observations of MLT in the SABER experiment It also allows reevaluating the thermalization efficiency of the absorbed solar ultraviolet energy and infrared radiative cooling/heating of MLT by detailed accounting of the electronic-vibrational relaxation of excited photolysis products via the complex chain of collisional energy conversion processes down to the vibrational energy of optically active trace gas molecules.
On the safety of ITER accelerators.
Li, Ge
2013-01-01
Three 1 MV/40A accelerators in heating neutral beams (HNB) are on track to be implemented in the International Thermonuclear Experimental Reactor (ITER). ITER may produce 500 MWt of power by 2026 and may serve as a green energy roadmap for the world. They will generate -1 MV 1 h long-pulse ion beams to be neutralised for plasma heating. Due to frequently occurring vacuum sparking in the accelerators, the snubbers are used to limit the fault arc current to improve ITER safety. However, recent analyses of its reference design have raised concerns. General nonlinear transformer theory is developed for the snubber to unify the former snubbers' different design models with a clear mechanism. Satisfactory agreement between theory and tests indicates that scaling up to a 1 MV voltage may be possible. These results confirm the nonlinear process behind transformer theory and map out a reliable snubber design for a safer ITER.
On the safety of ITER accelerators
Li, Ge
2013-01-01
Three 1 MV/40A accelerators in heating neutral beams (HNB) are on track to be implemented in the International Thermonuclear Experimental Reactor (ITER). ITER may produce 500 MWt of power by 2026 and may serve as a green energy roadmap for the world. They will generate −1 MV 1 h long-pulse ion beams to be neutralised for plasma heating. Due to frequently occurring vacuum sparking in the accelerators, the snubbers are used to limit the fault arc current to improve ITER safety. However, recent analyses of its reference design have raised concerns. General nonlinear transformer theory is developed for the snubber to unify the former snubbers' different design models with a clear mechanism. Satisfactory agreement between theory and tests indicates that scaling up to a 1 MV voltage may be possible. These results confirm the nonlinear process behind transformer theory and map out a reliable snubber design for a safer ITER. PMID:24008267
DOE Office of Scientific and Technical Information (OSTI.GOV)
Anisovich, A. V.
The reactionmore » $$\\gamma p \\to K^{*+} \\Lambda$$ was measured using the CLAS detector for photon energies between the threshold and 3.9 GeV at the Thomas Jefferson National Accelerator Facility. For the first time, spin-density matrix elements have been extracted for this reaction. Differential cross sections, spin density matrix elements, and the $$\\Lambda$$ recoil polarization are compared with theoretical predictions using the BnGa partial wave analysis. The main result is the evidence for significant contributions from $N(1895)1/2^-$ and $N(2100)1/2^+$ to the reaction. Branching ratios for decays into $$K^*\\Lambda$$ for these resonances and further resonances are reported.« less
Anisovich, A. V.
2017-05-16
The reactionmore » $$\\gamma p \\to K^{*+} \\Lambda$$ was measured using the CLAS detector for photon energies between the threshold and 3.9 GeV at the Thomas Jefferson National Accelerator Facility. For the first time, spin-density matrix elements have been extracted for this reaction. Differential cross sections, spin density matrix elements, and the $$\\Lambda$$ recoil polarization are compared with theoretical predictions using the BnGa partial wave analysis. The main result is the evidence for significant contributions from $N(1895)1/2^-$ and $N(2100)1/2^+$ to the reaction. Branching ratios for decays into $$K^*\\Lambda$$ for these resonances and further resonances are reported.« less
Computation of eigenpairs of Ax = lambda Bx for vibrations of spinning deformable bodies
NASA Technical Reports Server (NTRS)
Utku, S.; Clemente, J. L. M.
1984-01-01
It is shown that, when linear theory is used, the general eigenvalue problem related with the free vibrations of spinning deformable bodies is of the type AX = lambda Bx, where A is Hermitian, and B is real positive definite. Since the order n of the matrices may be large, and A and B are banded or block banded, due to the economics of the numerical solution, one is interested in obtaining only those eigenvalues which fall within the frequency band of interest of the problem. The paper extends the well known method of bisections and iteration of R to the n power to n dimensional complex spaces, i.e., to C to the n power, so that it can be applied to the present problem.
Hill, K W; Bitter, M L; Scott, S D; Ince-Cushman, A; Reinke, M; Rice, J E; Beiersdorfer, P; Gu, M-F; Lee, S G; Broennimann, Ch; Eikenberry, E F
2008-10-01
A new spatially resolving x-ray crystal spectrometer capable of measuring continuous spatial profiles of high resolution spectra (lambda/d lambda>6000) of He-like and H-like Ar K alpha lines with good spatial (approximately 1 cm) and temporal (approximately 10 ms) resolutions has been installed on the Alcator C-Mod tokamak. Two spherically bent crystals image the spectra onto four two-dimensional Pilatus II pixel detectors. Tomographic inversion enables inference of local line emissivity, ion temperature (T(i)), and toroidal plasma rotation velocity (upsilon(phi)) from the line Doppler widths and shifts. The data analysis techniques, T(i) and upsilon(phi) profiles, analysis of fusion-neutron background, and predictions of performance on other tokamaks, including ITER, will be presented.
Angelis, G I; Reader, A J; Markiewicz, P J; Kotasidis, F A; Lionheart, W R; Matthews, J C
2013-08-07
Recent studies have demonstrated the benefits of a resolution model within iterative reconstruction algorithms in an attempt to account for effects that degrade the spatial resolution of the reconstructed images. However, these algorithms suffer from slower convergence rates, compared to algorithms where no resolution model is used, due to the additional need to solve an image deconvolution problem. In this paper, a recently proposed algorithm, which decouples the tomographic and image deconvolution problems within an image-based expectation maximization (EM) framework, was evaluated. This separation is convenient, because more computational effort can be placed on the image deconvolution problem and therefore accelerate convergence. Since the computational cost of solving the image deconvolution problem is relatively small, multiple image-based EM iterations do not significantly increase the overall reconstruction time. The proposed algorithm was evaluated using 2D simulations, as well as measured 3D data acquired on the high-resolution research tomograph. Results showed that bias reduction can be accelerated by interleaving multiple iterations of the image-based EM algorithm solving the resolution model problem, with a single EM iteration solving the tomographic problem. Significant improvements were observed particularly for voxels that were located on the boundaries between regions of high contrast within the object being imaged and for small regions of interest, where resolution recovery is usually more challenging. Minor differences were observed using the proposed nested algorithm, compared to the single iteration normally performed, when an optimal number of iterations are performed for each algorithm. However, using the proposed nested approach convergence is significantly accelerated enabling reconstruction using far fewer tomographic iterations (up to 70% fewer iterations for small regions). Nevertheless, the optimal number of nested image-based EM iterations is hard to be defined and it should be selected according to the given application.
Kaluza-Klein cosmological model in f(R, T) gravity with Λ(T)
NASA Astrophysics Data System (ADS)
Sahoo, P. K.; Mishra, B.; Tripathy, S. K.
2016-04-01
A class of Kaluza-Klein cosmological models in $f(R,T)$ theory of gravity have been investigated. In the work, we have considered the functional $f(R,T)$ to be in the form $f(R,T)=f(R)+f(T)$ with $f(R)=\\lambda R$ and $f(T)=\\lambda T$. Such a choice of the functional $f(R,T)$ leads to an evolving effective cosmological constant $\\Lambda$ which depends on the stress energy tensor. The source of the matter field is taken to be a perfect cosmic fluid. The exact solutions of the field equations are obtained by considering a constant deceleration parameter which leads two different aspects of the volumetric expansion namely a power law and an exponential volumetric expansion. Keeping an eye on the accelerating nature of the universe in the present epoch, the dynamics and physical behaviour of the models have been discussed. From statefinder diagnostic pair we found that the model with exponential volumetric expansion behaves more like a $\\Lambda$CDM model.
Banerjee, Amartya S.; Suryanarayana, Phanish; Pask, John E.
2016-01-21
Pulay's Direct Inversion in the Iterative Subspace (DIIS) method is one of the most widely used mixing schemes for accelerating the self-consistent solution of electronic structure problems. In this work, we propose a simple generalization of DIIS in which Pulay extrapolation is performed at periodic intervals rather than on every self-consistent field iteration, and linear mixing is performed on all other iterations. Lastly, we demonstrate through numerical tests on a wide variety of materials systems in the framework of density functional theory that the proposed generalization of Pulay's method significantly improves its robustness and efficiency.
Time-resolved diffusion tomographic 2D and 3D imaging in highly scattering turbid media
NASA Technical Reports Server (NTRS)
Alfano, Robert R. (Inventor); Cai, Wei (Inventor); Liu, Feng (Inventor); Lax, Melvin (Inventor); Das, Bidyut B. (Inventor)
1999-01-01
A method for imaging objects in highly scattering turbid media. According to one embodiment of the invention, the method involves using a plurality of intersecting source/detectors sets and time-resolving equipment to generate a plurality of time-resolved intensity curves for the diffusive component of light emergent from the medium. For each of the curves, the intensities at a plurality of times are then inputted into the following inverse reconstruction algorithm to form an image of the medium: ##EQU1## wherein W is a matrix relating output at source and detector positions r.sub.s and r.sub.d, at time t, to position r, .LAMBDA. is a regularization matrix, chosen for convenience to be diagonal, but selected in a way related to the ratio of the noise,
Time-resolved diffusion tomographic 2D and 3D imaging in highly scattering turbid media
NASA Technical Reports Server (NTRS)
Alfano, Robert R. (Inventor); Cai, Wei (Inventor); Gayen, Swapan K. (Inventor)
2000-01-01
A method for imaging objects in highly scattering turbid media. According to one embodiment of the invention, the method involves using a plurality of intersecting source/detectors sets and time-resolving equipment to generate a plurality of time-resolved intensity curves for the diffusive component of light emergent from the medium. For each of the curves, the intensities at a plurality of times are then inputted into the following inverse reconstruction algorithm to form an image of the medium: wherein W is a matrix relating output at source and detector positions r.sub.s and r.sub.d, at time t, to position r, .LAMBDA. is a regularization matrix, chosen for convenience to be diagonal, but selected in a way related to the ratio of the noise,
NASA Technical Reports Server (NTRS)
Randol, Brent M.; Christian, Eric R.
2016-01-01
A parametric study is performed using the electrostatic simulations of Randol and Christian (2014) in which the number density, n, and initial thermal speed, theta, are varied. The range of parameters covers an extremely broad plasma regime, all the way from the very weak coupling of space plasmas to the very strong coupling of solid plasmas. The first result is that simulations at the same Lambda(sub D), where Lambda(sub D) is the plasma coupling parameter, but at different combinations of n and theta, behave exactly the same. As a function of Lambda(sub D), the form of p(v), the velocity distribution function of v, the magnitude of v, the velocity vector, is studied. For intermediate to high D, heating is observed in p(v) that obeys conservation of energy, and a suprathermal tail is formed, with a spectral index that depends on Lambda(sub D). For strong coupling (Lambda(sub D) much > 1), the form of the tail is v5, consistent with the findings of Randol and Christian (2014). For weak coupling (Lambda(sub D much <1), no acceleration or heating occurs, as there is no free energy. The dependence on N, the number of particles in the simulation, is also explored. There is a subtle dependence in the index of the tail, such that v5 appears to be the N approaches infinity limit.
Transport synthetic acceleration with opposing reflecting boundary conditions
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zika, M.R.; Adams, M.L.
2000-02-01
The transport synthetic acceleration (TSA) scheme is extended to problems with opposing reflecting boundary conditions. This synthetic method employs a simplified transport operator as its low-order approximation. A procedure is developed that allows the use of the conjugate gradient (CG) method to solve the resulting low-order system of equations. Several well-known transport iteration algorithms are cast in a linear algebraic form to show their equivalence to standard iterative techniques. Source iteration in the presence of opposing reflecting boundary conditions is shown to be equivalent to a (poorly) preconditioned stationary Richardson iteration, with the preconditioner defined by the method of iteratingmore » on the incident fluxes on the reflecting boundaries. The TSA method (and any synthetic method) amounts to a further preconditioning of the Richardson iteration. The presence of opposing reflecting boundary conditions requires special consideration when developing a procedure to realize the CG method for the proposed system of equations. The CG iteration may be applied only to symmetric positive definite matrices; this condition requires the algebraic elimination of the boundary angular corrections from the low-order equations. As a consequence of this elimination, evaluating the action of the resulting matrix on an arbitrary vector involves two transport sweeps and a transmission iteration. Results of applying the acceleration scheme to a simple test problem are presented.« less
New Kinematical Constraints on Cosmic Acceleration
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rapetti, David; Allen, Steve W.; Amin, Mustafa A.
2007-05-25
We present and employ a new kinematical approach to ''dark energy'' studies. We construct models in terms of the dimensionless second and third derivatives of the scale factor a(t) with respect to cosmic time t, namely the present-day value of the deceleration parameter q{sub 0} and the cosmic jerk parameter, j(t). An elegant feature of this parameterization is that all {Lambda}CDM models have j(t)=1 (constant), which facilitates simple tests for departures from the {Lambda}CDM paradigm. Applying our model to redshift-independent distance measurements, from type Ia supernovae and X-ray cluster gas mass fraction measurements, we obtain clear statistical evidence for amore » late time transition from a decelerating to an accelerating phase. For a flat model with constant jerk, j(t)=j, we measure q{sub 0}=-0.81 {+-} 0.14 and j=2.16 +0.81 -0.75, results that are consistent with {Lambda}CDM at about the 1{sigma} confidence level. In comparison to dynamical analyses, the kinematical approach uses a different model set and employs a minimum of prior information, being independent of any particular gravity theory. The results obtained with this new approach therefore provide important additional information and we argue that both kinematical and dynamical techniques should be employed in future dark energy studies, where possible.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Xu, Qiaofeng; Sawatzky, Alex; Anastasio, Mark A., E-mail: anastasio@wustl.edu
Purpose: The development of iterative image reconstruction algorithms for cone-beam computed tomography (CBCT) remains an active and important research area. Even with hardware acceleration, the overwhelming majority of the available 3D iterative algorithms that implement nonsmooth regularizers remain computationally burdensome and have not been translated for routine use in time-sensitive applications such as image-guided radiation therapy (IGRT). In this work, two variants of the fast iterative shrinkage thresholding algorithm (FISTA) are proposed and investigated for accelerated iterative image reconstruction in CBCT. Methods: Algorithm acceleration was achieved by replacing the original gradient-descent step in the FISTAs by a subproblem that ismore » solved by use of the ordered subset simultaneous algebraic reconstruction technique (OS-SART). Due to the preconditioning matrix adopted in the OS-SART method, two new weighted proximal problems were introduced and corresponding fast gradient projection-type algorithms were developed for solving them. We also provided efficient numerical implementations of the proposed algorithms that exploit the massive data parallelism of multiple graphics processing units. Results: The improved rates of convergence of the proposed algorithms were quantified in computer-simulation studies and by use of clinical projection data corresponding to an IGRT study. The accelerated FISTAs were shown to possess dramatically improved convergence properties as compared to the standard FISTAs. For example, the number of iterations to achieve a specified reconstruction error could be reduced by an order of magnitude. Volumetric images reconstructed from clinical data were produced in under 4 min. Conclusions: The FISTA achieves a quadratic convergence rate and can therefore potentially reduce the number of iterations required to produce an image of a specified image quality as compared to first-order methods. We have proposed and investigated accelerated FISTAs for use with two nonsmooth penalty functions that will lead to further reductions in image reconstruction times while preserving image quality. Moreover, with the help of a mixed sparsity-regularization, better preservation of soft-tissue structures can be potentially obtained. The algorithms were systematically evaluated by use of computer-simulated and clinical data sets.« less
Xu, Qiaofeng; Yang, Deshan; Tan, Jun; Sawatzky, Alex; Anastasio, Mark A
2016-04-01
The development of iterative image reconstruction algorithms for cone-beam computed tomography (CBCT) remains an active and important research area. Even with hardware acceleration, the overwhelming majority of the available 3D iterative algorithms that implement nonsmooth regularizers remain computationally burdensome and have not been translated for routine use in time-sensitive applications such as image-guided radiation therapy (IGRT). In this work, two variants of the fast iterative shrinkage thresholding algorithm (FISTA) are proposed and investigated for accelerated iterative image reconstruction in CBCT. Algorithm acceleration was achieved by replacing the original gradient-descent step in the FISTAs by a subproblem that is solved by use of the ordered subset simultaneous algebraic reconstruction technique (OS-SART). Due to the preconditioning matrix adopted in the OS-SART method, two new weighted proximal problems were introduced and corresponding fast gradient projection-type algorithms were developed for solving them. We also provided efficient numerical implementations of the proposed algorithms that exploit the massive data parallelism of multiple graphics processing units. The improved rates of convergence of the proposed algorithms were quantified in computer-simulation studies and by use of clinical projection data corresponding to an IGRT study. The accelerated FISTAs were shown to possess dramatically improved convergence properties as compared to the standard FISTAs. For example, the number of iterations to achieve a specified reconstruction error could be reduced by an order of magnitude. Volumetric images reconstructed from clinical data were produced in under 4 min. The FISTA achieves a quadratic convergence rate and can therefore potentially reduce the number of iterations required to produce an image of a specified image quality as compared to first-order methods. We have proposed and investigated accelerated FISTAs for use with two nonsmooth penalty functions that will lead to further reductions in image reconstruction times while preserving image quality. Moreover, with the help of a mixed sparsity-regularization, better preservation of soft-tissue structures can be potentially obtained. The algorithms were systematically evaluated by use of computer-simulated and clinical data sets.
Xu, Qiaofeng; Yang, Deshan; Tan, Jun; Sawatzky, Alex; Anastasio, Mark A.
2016-01-01
Purpose: The development of iterative image reconstruction algorithms for cone-beam computed tomography (CBCT) remains an active and important research area. Even with hardware acceleration, the overwhelming majority of the available 3D iterative algorithms that implement nonsmooth regularizers remain computationally burdensome and have not been translated for routine use in time-sensitive applications such as image-guided radiation therapy (IGRT). In this work, two variants of the fast iterative shrinkage thresholding algorithm (FISTA) are proposed and investigated for accelerated iterative image reconstruction in CBCT. Methods: Algorithm acceleration was achieved by replacing the original gradient-descent step in the FISTAs by a subproblem that is solved by use of the ordered subset simultaneous algebraic reconstruction technique (OS-SART). Due to the preconditioning matrix adopted in the OS-SART method, two new weighted proximal problems were introduced and corresponding fast gradient projection-type algorithms were developed for solving them. We also provided efficient numerical implementations of the proposed algorithms that exploit the massive data parallelism of multiple graphics processing units. Results: The improved rates of convergence of the proposed algorithms were quantified in computer-simulation studies and by use of clinical projection data corresponding to an IGRT study. The accelerated FISTAs were shown to possess dramatically improved convergence properties as compared to the standard FISTAs. For example, the number of iterations to achieve a specified reconstruction error could be reduced by an order of magnitude. Volumetric images reconstructed from clinical data were produced in under 4 min. Conclusions: The FISTA achieves a quadratic convergence rate and can therefore potentially reduce the number of iterations required to produce an image of a specified image quality as compared to first-order methods. We have proposed and investigated accelerated FISTAs for use with two nonsmooth penalty functions that will lead to further reductions in image reconstruction times while preserving image quality. Moreover, with the help of a mixed sparsity-regularization, better preservation of soft-tissue structures can be potentially obtained. The algorithms were systematically evaluated by use of computer-simulated and clinical data sets. PMID:27036582
Status of the 1 MeV Accelerator Design for ITER NBI
NASA Astrophysics Data System (ADS)
Kuriyama, M.; Boilson, D.; Hemsworth, R.; Svensson, L.; Graceffa, J.; Schunke, B.; Decamps, H.; Tanaka, M.; Bonicelli, T.; Masiello, A.; Bigi, M.; Chitarin, G.; Luchetta, A.; Marcuzzi, D.; Pasqualotto, R.; Pomaro, N.; Serianni, G.; Sonato, P.; Toigo, V.; Zaccaria, P.; Kraus, W.; Franzen, P.; Heinemann, B.; Inoue, T.; Watanabe, K.; Kashiwagi, M.; Taniguchi, M.; Tobari, H.; De Esch, H.
2011-09-01
The beam source of neutral beam heating/current drive system for ITER is needed to accelerate the negative ion beam of 40A with D- at 1 MeV for 3600 sec. In order to realize the beam source, design and R&D works are being developed in many institutions under the coordination of ITER organization. The development of the key issues of the ion source including source plasma uniformity, suppression of co-extracted electron in D beam operation and also after the long beam duration time of over a few 100 sec, is progressed mainly in IPP with the facilities of BATMAN, MANITU and RADI. In the near future, ELISE, that will be tested the half size of the ITER ion source, will start the operation in 2011, and then SPIDER, which demonstrates negative ion production and extraction with the same size and same structure as the ITER ion source, will start the operation in 2014 as part of the NBTF. The development of the accelerator is progressed mainly in JAEA with the MeV test facility, and also the computer simulation of beam optics also developed in JAEA, CEA and RFX. The full ITER heating and current drive beam performance will be demonstrated in MITICA, which will start operation in 2016 as part of the NBTF.
The Nature of the UV/X-ray Absorber In PG 2302+029
NASA Technical Reports Server (NTRS)
Sabra, Bassem M.; Hamann, Fred; Jannuzi, Buell T.; George, Ian M.; Shields, Joseph C.
2003-01-01
We present Chandra X-ray observations of the radio-quiet QSO PG 2302+029. This quasar has a rare system of ultra-high velocity (-56,000 km s(exp -1) UV absorption lines that form in an outflow from the active nucleus. The Chandra data indicate that soft X-ray absorption is also present. We perform a joint UV and X-ray analysis, using photoionization calculations, to determine the nature of the absorbing gas. The UV and X-ray datasets were not obtained simultaneously. Nonetheless, our analysis suggests that the X-ray absorption occurs at high velocities in the same general region as the UV absorber. There are not enough constraints to rule out multi-zone models. In fact, the distinct broad and narrow UV line profiles clearly indicate that multiple zones are present. Our preferred estimates of the ionization and total column density in the X-ray absorber (logU = 1.6, N(sub eta) = 10(exp 22.4) cm (exp -2) over predict the O VI lambda lambda1032,1038 absorption unless the X-ray absorber is also outflowing at approximately 56,000 km s(exp-l), but they over predict the Ne VIII lambda lambda 770,780 absorption at all velocities. If we assume that the X-ray absorbing gas is outflowing at the same velocity of the UV-absorbing wind and that the wind is radiatively accelerated, then the outflow must be launched at a radius of less than or equal to 10(exp 15) cm from the central continuum source. The smallness of this radius casts doubts on the assumption of radiative acceleration.
Overview of the design of the ITER heating neutral beam injectors
NASA Astrophysics Data System (ADS)
Hemsworth, R. S.; Boilson, D.; Blatchford, P.; Dalla Palma, M.; Chitarin, G.; de Esch, H. P. L.; Geli, F.; Dremel, M.; Graceffa, J.; Marcuzzi, D.; Serianni, G.; Shah, D.; Singh, M.; Urbani, M.; Zaccaria, P.
2017-02-01
The heating neutral beam injectors (HNBs) of ITER are designed to deliver 16.7 MW of 1 MeV D0 or 0.87 MeV H0 to the ITER plasma for up to 3600 s. They will be the most powerful neutral beam (NB) injectors ever, delivering higher energy NBs to the plasma in a tokamak for longer than any previous systems have done. The design of the HNBs is based on the acceleration and neutralisation of negative ions as the efficiency of conversion of accelerated positive ions is so low at the required energy that a realistic design is not possible, whereas the neutralisation of H- and D- remains acceptable (≈56%). The design of a long pulse negative ion based injector is inherently more complicated than that of short pulse positive ion based injectors because: • negative ions are harder to create so that they can be extracted and accelerated from the ion source; • electrons can be co-extracted from the ion source along with the negative ions, and their acceleration must be minimised to maintain an acceptable overall accelerator efficiency; • negative ions are easily lost by collisions with the background gas in the accelerator; • electrons created in the extractor and accelerator can impinge on the extraction and acceleration grids, leading to high power loads on the grids; • positive ions are created in the accelerator by ionisation of the background gas by the accelerated negative ions and the positive ions are back-accelerated into the ion source creating a massive power load to the ion source; • electrons that are co-accelerated with the negative ions can exit the accelerator and deposit power on various downstream beamline components. The design of the ITER HNBs is further complicated because ITER is a nuclear installation which will generate very large fluxes of neutrons and gamma rays. Consequently all the injector components have to survive in that harsh environment. Additionally the beamline components and the NB cell, where the beams are housed, will be activated and all maintenance will have to be performed remotely. This paper describes the design of the HNB injectors, but not the associated power supplies, cooling system, cryogenic system etc, or the high voltage bushing which separates the vacuum of the beamline from the high pressure SF6 of the high voltage (1 MV) transmission line, through which the power, gas and cooling water are supplied to the beam source. Also the magnetic field reduction system is not described.
Matching into the Helical Bunch Coalescing Channel for a High Luminosity Muon Collider
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sy, Amy; Ankenbrandt, Charles; Derbenev, Yaroslav
2015-09-01
For high luminosity in a muon collider, muon bunches that have been cooled in the six-dimensional helical cooling channel (HCC) must be merged into a single bunch and further cooled in preparation for acceleration and transport to the collider ring. The helical bunch coalescing channel has been previously simulated and provides the most natural match from helical upstream and downstream subsystems. This work focuses on the matching from the exit of the multiple bunch HCC into the start of the helical bunch coalescing channel. The simulated helical matching section simultaneously matches the helical spatial period lambda in addition to providingmore » the necessary acceleration for efficient bunch coalescing. Previous studies assumed that the acceleration of muon bunches from p=209.15 MeV/c to 286.816 MeV/c and matching of lambda from 0.5 m to 1.0 m could be accomplished with zero particle losses and zero emittance growth in the individual bunches. This study demonstrates nonzero values for both particle loss and emittance growth, and provides considerations for reducing these adverse effects to best preserve high luminosity.« less
Fourier mode analysis of slab-geometry transport iterations in spatially periodic media
DOE Office of Scientific and Technical Information (OSTI.GOV)
Larsen, E; Zika, M
1999-04-01
We describe a Fourier analysis of the diffusion-synthetic acceleration (DSA) and transport-synthetic acceleration (TSA) iteration schemes for a spatially periodic, but otherwise arbitrarily heterogeneous, medium. Both DSA and TSA converge more slowly in a heterogeneous medium than in a homogeneous medium composed of the volume-averaged scattering ratio. In the limit of a homogeneous medium, our heterogeneous analysis contains eigenvalues of multiplicity two at ''resonant'' wave numbers. In the presence of material heterogeneities, error modes corresponding to these resonant wave numbers are ''excited'' more than other error modes. For DSA and TSA, the iteration spectral radius may occur at these resonantmore » wave numbers, in which case the material heterogeneities most strongly affect iterative performance.« less
Analysis of Anderson Acceleration on a Simplified Neutronics/Thermal Hydraulics System
DOE Office of Scientific and Technical Information (OSTI.GOV)
Toth, Alex; Kelley, C. T.; Slattery, Stuart R
ABSTRACT A standard method for solving coupled multiphysics problems in light water reactors is Picard iteration, which sequentially alternates between solving single physics applications. This solution approach is appealing due to simplicity of implementation and the ability to leverage existing software packages to accurately solve single physics applications. However, there are several drawbacks in the convergence behavior of this method; namely slow convergence and the necessity of heuristically chosen damping factors to achieve convergence in many cases. Anderson acceleration is a method that has been seen to be more robust and fast converging than Picard iteration for many problems, withoutmore » significantly higher cost per iteration or complexity of implementation, though its effectiveness in the context of multiphysics coupling is not well explored. In this work, we develop a one-dimensional model simulating the coupling between the neutron distribution and fuel and coolant properties in a single fuel pin. We show that this model generally captures the convergence issues noted in Picard iterations which couple high-fidelity physics codes. We then use this model to gauge potential improvements with regard to rate of convergence and robustness from utilizing Anderson acceleration as an alternative to Picard iteration.« less
Local Improvement Results for Anderson Acceleration with Inaccurate Function Evaluations
Toth, Alex; Ellis, J. Austin; Evans, Tom; ...
2017-10-26
Here, we analyze the convergence of Anderson acceleration when the fixed point map is corrupted with errors. We also consider uniformly bounded errors and stochastic errors with infinite tails. We prove local improvement results which describe the performance of the iteration up to the point where the accuracy of the function evaluation causes the iteration to stagnate. We illustrate the results with examples from neutronics.
Local Improvement Results for Anderson Acceleration with Inaccurate Function Evaluations
DOE Office of Scientific and Technical Information (OSTI.GOV)
Toth, Alex; Ellis, J. Austin; Evans, Tom
Here, we analyze the convergence of Anderson acceleration when the fixed point map is corrupted with errors. We also consider uniformly bounded errors and stochastic errors with infinite tails. We prove local improvement results which describe the performance of the iteration up to the point where the accuracy of the function evaluation causes the iteration to stagnate. We illustrate the results with examples from neutronics.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Roat, C
A measurement of {Beta}({Lambda}{sub c}{sup +} {yields} pK{sup -} {pi}{sup +}) is presented based on data collected with the BaBar detector at the Stanford Linear Accelerator Center. Branching fraction measurements represent a large portion of what is known about short-lived particles, the strong force that binds them, and the weak force that causes them to decay. While the majority of branching fraction measurements are done as ratios between two decay modes, it is the absolute measurements of a few particular decay modes that set the scale for these relative measurements. The {Lambda}{sub c}{sup +} particle is one of the fourmore » weakly decaying hadrons into which more than 90% of the known heavy quark hadrons will eventually decay. Thus, an absolute measurement of the branching fraction for {Lambda}{sub c}{sup +} {yields} pK{sup -}{pi}{sup +} is important for many studies of the heavy quark sector, from spectroscopy to B meson decays. The number of produced {Lambda}{sub c}{sup +}'s is inferred from the number of events reconstructed with an antiproton and an accompanying D meson. The final result of {Beta}({Lambda}{sub c}{sup +} {yields} pK{sup -} {pi}{sup +}) = [6.12 {+-} 0.31(stat.) {+-} 0.42(syst.)]% represents more than a two-fold improvement in precision over the world average. The dominant source of systematic uncertainty is the irreducible background of {Xi}{sub c} baryons.« less
Apparatus for neutralization of accelerated ions
Fink, Joel H.; Frank, Alan M.
1979-01-01
Apparatus for neutralization of a beam of accelerated ions, such as hydrogen negative ions (H.sup.-), using relatively efficient strip diode lasers which emit monochromatically at an appropriate wavelength (.lambda. = 8000 A for H.sup.- ions) to strip the excess electrons by photodetachment. A cavity, formed by two or more reflectors spaced apart, causes the laser beams to undergo multiple reflections within the cavity, thus increasing the efficiency and reducing the illumination required to obtain an acceptable percentage (.about. 85%) of neutralization.
Pratapa, Phanisri P.; Suryanarayana, Phanish; Pask, John E.
2015-12-01
We employ Anderson extrapolation to accelerate the classical Jacobi iterative method for large, sparse linear systems. Specifically, we utilize extrapolation at periodic intervals within the Jacobi iteration to develop the Alternating Anderson–Jacobi (AAJ) method. We verify the accuracy and efficacy of AAJ in a range of test cases, including nonsymmetric systems of equations. We demonstrate that AAJ possesses a favorable scaling with system size that is accompanied by a small prefactor, even in the absence of a preconditioner. In particular, we show that AAJ is able to accelerate the classical Jacobi iteration by over four orders of magnitude, with speed-upsmore » that increase as the system gets larger. Moreover, we find that AAJ significantly outperforms the Generalized Minimal Residual (GMRES) method in the range of problems considered here, with the relative performance again improving with size of the system. As a result, the proposed method represents a simple yet efficient technique that is particularly attractive for large-scale parallel solutions of linear systems of equations.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pratapa, Phanisri P.; Suryanarayana, Phanish; Pask, John E.
We employ Anderson extrapolation to accelerate the classical Jacobi iterative method for large, sparse linear systems. Specifically, we utilize extrapolation at periodic intervals within the Jacobi iteration to develop the Alternating Anderson–Jacobi (AAJ) method. We verify the accuracy and efficacy of AAJ in a range of test cases, including nonsymmetric systems of equations. We demonstrate that AAJ possesses a favorable scaling with system size that is accompanied by a small prefactor, even in the absence of a preconditioner. In particular, we show that AAJ is able to accelerate the classical Jacobi iteration by over four orders of magnitude, with speed-upsmore » that increase as the system gets larger. Moreover, we find that AAJ significantly outperforms the Generalized Minimal Residual (GMRES) method in the range of problems considered here, with the relative performance again improving with size of the system. As a result, the proposed method represents a simple yet efficient technique that is particularly attractive for large-scale parallel solutions of linear systems of equations.« less
POLARIZED LINE FORMATION IN NON-MONOTONIC VELOCITY FIELDS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sampoorna, M.; Nagendra, K. N., E-mail: sampoorna@iiap.res.in, E-mail: knn@iiap.res.in
2016-12-10
For a correct interpretation of the observed spectro-polarimetric data from astrophysical objects such as the Sun, it is necessary to solve the polarized line transfer problems taking into account a realistic temperature structure, the dynamical state of the atmosphere, a realistic scattering mechanism (namely, the partial frequency redistribution—PRD), and the magnetic fields. In a recent paper, we studied the effects of monotonic vertical velocity fields on linearly polarized line profiles formed in isothermal atmospheres with and without magnetic fields. However, in general the velocity fields that prevail in dynamical atmospheres of astrophysical objects are non-monotonic. Stellar atmospheres with shocks, multi-componentmore » supernova atmospheres, and various kinds of wave motions in solar and stellar atmospheres are examples of non-monotonic velocity fields. Here we present studies on the effect of non-relativistic non-monotonic vertical velocity fields on the linearly polarized line profiles formed in semi-empirical atmospheres. We consider a two-level atom model and PRD scattering mechanism. We solve the polarized transfer equation in the comoving frame (CMF) of the fluid using a polarized accelerated lambda iteration method that has been appropriately modified for the problem at hand. We present numerical tests to validate the CMF method and also discuss the accuracy and numerical instabilities associated with it.« less
Multiprocessor smalltalk: Implementation, performance, and analysis
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pallas, J.I.
1990-01-01
Multiprocessor Smalltalk demonstrates the value of object-oriented programming on a multiprocessor. Its implementation and analysis shed light on three areas: concurrent programming in an object oriented language without special extensions, implementation techniques for adapting to multiprocessors, and performance factors in the resulting system. Adding parallelism to Smalltalk code is easy, because programs already use control abstractions like iterators. Smalltalk's basic control and concurrency primitives (lambda expressions, processes and semaphores) can be used to build parallel control abstractions, including parallel iterators, parallel objects, atomic objects, and futures. Language extensions for concurrency are not required. This implementation demonstrates that it is possiblemore » to build an efficient parallel object-oriented programming system and illustrates techniques for doing so. Three modification tools-serialization, replication, and reorganization-adapted the Berkeley Smalltalk interpreter to the Firefly multiprocessor. Multiprocessor Smalltalk's performance shows that the combination of multiprocessing and object-oriented programming can be effective: speedups (relative to the original serial version) exceed 2.0 for five processors on all the benchmarks; the median efficiency is 48%. Analysis shows both where performance is lost and how to improve and generalize the experimental results. Changes in the interpreter to support concurrency add at most 12% overhead; better access to per-process variables could eliminate much of that. Changes in the user code to express concurrency add as much as 70% overhead; this overhead could be reduced to 54% if blocks (lambda expressions) were reentrant. Performance is also lost when the program cannot keep all five processors busy.« less
Fast divide-and-conquer algorithm for evaluating polarization in classical force fields
NASA Astrophysics Data System (ADS)
Nocito, Dominique; Beran, Gregory J. O.
2017-03-01
Evaluation of the self-consistent polarization energy forms a major computational bottleneck in polarizable force fields. In large systems, the linear polarization equations are typically solved iteratively with techniques based on Jacobi iterations (JI) or preconditioned conjugate gradients (PCG). Two new variants of JI are proposed here that exploit domain decomposition to accelerate the convergence of the induced dipoles. The first, divide-and-conquer JI (DC-JI), is a block Jacobi algorithm which solves the polarization equations within non-overlapping sub-clusters of atoms directly via Cholesky decomposition, and iterates to capture interactions between sub-clusters. The second, fuzzy DC-JI, achieves further acceleration by employing overlapping blocks. Fuzzy DC-JI is analogous to an additive Schwarz method, but with distance-based weighting when averaging the fuzzy dipoles from different blocks. Key to the success of these algorithms is the use of K-means clustering to identify natural atomic sub-clusters automatically for both algorithms and to determine the appropriate weights in fuzzy DC-JI. The algorithm employs knowledge of the 3-D spatial interactions to group important elements in the 2-D polarization matrix. When coupled with direct inversion in the iterative subspace (DIIS) extrapolation, fuzzy DC-JI/DIIS in particular converges in a comparable number of iterations as PCG, but with lower computational cost per iteration. In the end, the new algorithms demonstrated here accelerate the evaluation of the polarization energy by 2-3 fold compared to existing implementations of PCG or JI/DIIS.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Aubert, B.; Bona, M.; Boutigny, D.
We present a study of excited charm-strange baryon states produced in e{sup +}e{sup -} annihilations at or near a center-of-mass energy of 10.58 GeV, in a data sample with an integrated luminosity of 384 fb{sup -1} recorded with the BABAR detector at the PEP-II e{sup +}e{sup -} storage rings at the Stanford Linear Accelerator Center. We study strong decays of charm-strange baryons to {lambda}{sub c}{sup +}K{sub S}{sup 0}, {lambda}{sub c}{sup +}K{sup -}, {lambda}{sub c}{sup +}K{sup -}{pi}{sup +}, {lambda}{sub c}{sup +}K{sub S}{sup 0}{pi}{sup -}, {lambda}{sub c}{sup +}K{sub S}{sup 0}{pi}{sup -}{pi}{sup +}, and {lambda}{sub c}{sup +}K{sup -}{pi}{sup +}{pi}{sup -}. This study confirmsmore » the existence of the states {xi}{sub c}(2980){sup +}, {xi}{sub c}(3077){sup +}, and {xi}{sub c}(3077){sup 0}, with a more accurate determination of the {xi}{sub c}(2980){sup +} mass and width. We also present evidence for two new states, {xi}{sub c}(3055){sup +} and {xi}{sub c}(3123){sup +}, decaying through the intermediate-resonant modes {sigma}{sub c}(2455){sup ++}K{sup -} and {sigma}{sub c}(2520){sup ++}K{sup -}, respectively. For each of these baryons, we measure the yield in each final state, determine the statistical significance, and calculate the product of the production cross section and branching fractions. We also measure the masses and widths of these excited charm-strange baryons.« less
NASA Astrophysics Data System (ADS)
Ahunov, Roman R.; Kuksenko, Sergey P.; Gazizov, Talgat R.
2016-06-01
A multiple solution of linear algebraic systems with dense matrix by iterative methods is considered. To accelerate the process, the recomputing of the preconditioning matrix is used. A priory condition of the recomputing based on change of the arithmetic mean of the current solution time during the multiple solution is proposed. To confirm the effectiveness of the proposed approach, the numerical experiments using iterative methods BiCGStab and CGS for four different sets of matrices on two examples of microstrip structures are carried out. For solution of 100 linear systems the acceleration up to 1.6 times, compared to the approach without recomputing, is obtained.
Spectrum transformation for divergent iterations
NASA Technical Reports Server (NTRS)
Gupta, Murli M.
1991-01-01
Certain spectrum transformation techniques are described that can be used to transform a diverging iteration into a converging one. Two techniques are considered called spectrum scaling and spectrum enveloping and how to obtain the optimum values of the transformation parameters is discussed. Numerical examples are given to show how this technique can be used to transform diverging iterations into converging ones; this technique can also be used to accelerate the convergence of otherwise convergent iterations.
KINETIC ALFVEN WAVES EXCITED BY OBLIQUE MAGNETOHYDRODYNAMIC ALFVEN WAVES IN CORONAL HOLES
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhao, J. S.; Wu, D. J.; Lu, J. Y., E-mail: js_zhao@pmo.ac.cn, E-mail: djwu@pmo.ac.cn, E-mail: lujy@cma.gov.cn
Kinetic Alfven waves (KAWs) are small-scale dispersive AWs that can play an important role in particle heating and acceleration of space and solar plasmas. An excitation mechanism for KAWs created by the coupling between large-scale oblique AWs and small-scale KAWs is presented in this paper. Taking into account both the collisional and Landau damping dissipations, the results show that the net growth rate of the excited KAWs increases with their perpendicular wavenumber k{sub perpendicular} and reaches maximum at {lambda}{sub e} k{sub perpendicular} {approx} 0.3, where {lambda}{sub e} is the electron inertial length. However, for KAWs with shorter perpendicular wavelengths, themore » net growth rate decreases rapidly due to dissipative effects. The evaluation of the threshold amplitude of the AW implies that for KAWs with {lambda}{sub e} k{sub perpendicular} < 0.3, the relative threshold amplitude is well below 10%, which is easy to satisfy. In particular, when applying this mechanism to the case of a solar coronal hole containing a dense plume structure, our results show that KAWs with {lambda}{sub e} k{sub perpendicular} < 0.3 can be not only efficiently excited in the interplume region but also strongly dissipated in the dense plume due to the Landau damping.« less
NASA Astrophysics Data System (ADS)
Bosch, Carl; Degirmenci, Soysal; Barlow, Jason; Mesika, Assaf; Politte, David G.; O'Sullivan, Joseph A.
2016-05-01
X-ray computed tomography reconstruction for medical, security and industrial applications has evolved through 40 years of experience with rotating gantry scanners using analytic reconstruction techniques such as filtered back projection (FBP). In parallel, research into statistical iterative reconstruction algorithms has evolved to apply to sparse view scanners in nuclear medicine, low data rate scanners in Positron Emission Tomography (PET) [5, 7, 10] and more recently to reduce exposure to ionizing radiation in conventional X-ray CT scanners. Multiple approaches to statistical iterative reconstruction have been developed based primarily on variations of expectation maximization (EM) algorithms. The primary benefit of EM algorithms is the guarantee of convergence that is maintained when iterative corrections are made within the limits of convergent algorithms. The primary disadvantage, however is that strict adherence to correction limits of convergent algorithms extends the number of iterations and ultimate timeline to complete a 3D volumetric reconstruction. Researchers have studied methods to accelerate convergence through more aggressive corrections [1], ordered subsets [1, 3, 4, 9] and spatially variant image updates. In this paper we describe the development of an AM reconstruction algorithm with accelerated convergence for use in a real-time explosive detection application for aviation security. By judiciously applying multiple acceleration techniques and advanced GPU processing architectures, we are able to perform 3D reconstruction of scanned passenger baggage at a rate of 75 slices per second. Analysis of the results on stream of commerce passenger bags demonstrates accelerated convergence by factors of 8 to 15, when comparing images from accelerated and strictly convergent algorithms.
Long pulse acceleration of MeV class high power density negative H{sup −} ion beam for ITER
DOE Office of Scientific and Technical Information (OSTI.GOV)
Umeda, N., E-mail: umeda.naotaka@jaea.go.jp; Kojima, A.; Kashiwagi, M.
2015-04-08
R and D of high power density negative ion beam acceleration has been carried out at MeV test facility in JAEA to realize ITER neutral beam accelerator. The main target is H{sup −} ion beam acceleration up to 1 MeV with 200 A/m{sup 2} for 60 s whose pulse length is the present facility limit. For long pulse acceleration at high power density, new extraction grid (EXG) has been developed with high cooling capability, which electron suppression magnet is placed under cooling channel similar to ITER. In addition, aperture size of electron suppression grid (ESG) is enlarged from 14 mmmore » to 16 mm to reduce direct interception on the ESG and emission of secondary electron which leads to high heat load on the upstream acceleration grid. By enlarging ESG aperture, beam current increased 10 % at high current beam and total acceleration grid heat load reduced from 13 % to 10 % of input power at long pulse beam. In addition, heat load by back stream positive ion into the EXG is measured for the first time and is estimated as 0.3 % of beam power, while heat load by back stream ion into the source chamber is estimated as 3.5 ~ 4.0 % of beam power. Beam acceleration up to 60 s which is the facility limit, has achieved at 683 keV, 100 A/m{sup 2} of negative ion beam, whose energy density increases two orders of magnitude since 2011.« less
Choosing order of operations to accelerate strip structure analysis in parameter range
NASA Astrophysics Data System (ADS)
Kuksenko, S. P.; Akhunov, R. R.; Gazizov, T. R.
2018-05-01
The paper considers the issue of using iteration methods in solving the sequence of linear algebraic systems obtained in quasistatic analysis of strip structures with the method of moments. Using the analysis of 4 strip structures, the authors have proved that additional acceleration (up to 2.21 times) of the iterative process can be obtained during the process of solving linear systems repeatedly by means of choosing a proper order of operations and a preconditioner. The obtained results can be used to accelerate the process of computer-aided design of various strip structures. The choice of the order of operations to accelerate the process is quite simple, universal and could be used not only for strip structure analysis but also for a wide range of computational problems.
A Fast and Accurate Algorithm for l1 Minimization Problems in Compressive Sampling (Preprint)
2013-01-22
However, updating uk+1 via the formulation of Step 2 in Algorithm 1 can be implemented through the use of the component-wise Gauss - Seidel iteration which...may accelerate the rate of convergence of the algorithm and therefore reduce the total CPU-time consumed. The efficiency of component-wise Gauss - Seidel ...Micchelli, L. Shen, and Y. Xu, A proximity algorithm accelerated by Gauss - Seidel iterations for L1/TV denoising models, Inverse Problems, 28 (2012), p
Eigenproblem solution by a combined Sturm sequence and inverse iteration technique.
NASA Technical Reports Server (NTRS)
Gupta, K. K.
1973-01-01
Description of an efficient and numerically stable algorithm, along with a complete listing of the associated computer program, developed for the accurate computation of specified roots and associated vectors of the eigenvalue problem Aq = lambda Bq with band symmetric A and B, B being also positive-definite. The desired roots are first isolated by the Sturm sequence procedure; then a special variant of the inverse iteration technique is applied for the individual determination of each root along with its vector. The algorithm fully exploits the banded form of relevant matrices, and the associated program written in FORTRAN V for the JPL UNIVAC 1108 computer proves to be most significantly economical in comparison to similar existing procedures. The program may be conveniently utilized for the efficient solution of practical engineering problems, involving free vibration and buckling analysis of structures. Results of such analyses are presented for representative structures.
Results of Detailed Modeling of the Narrow-Line Region of Seyfert Galaxies
NASA Technical Reports Server (NTRS)
Moore, David; Cohen, Ross D.
1996-01-01
We present model line profiles of [O II] lambda3727, [Ne III] lambda3869, [O I] lambda5007, [Fe VII] lambda6087, [Fe X] lambda6374, [O I] lambda6300, H(alpha) lambda6563, and [S 2] lambda6731. The profiles presented here illustrate explicitly the pronounced effects that collisional de-excitation, and that spatial variations in both the ionization parameter and cloud column density, have on Narrow-Line Region (NLR) model profiles. The above effects were included only qualitatively in a previous analytical treatment by Moore and Cohen. By making a direct correspondence between these model profiles and the analytical model profiles of Moore and Cohen, and by comparing with the observed profiles presented in a companion paper and also with those presented elsewhere in the literature, we strengthen some of the conclusions of Moore and Cohen. Most notably, we argue for constant ionization parameter, uniformly accelerated outflow of clouds that are individually stratified in ionization, and the interpretation of emission-line width correlations with ionization potential as a column density effect. For comparison with previous observational studies, such as our own in a companion paper, we also calculate profile parameters for some of the models, and we present and discuss the resulting line width correlations with critical density (n(sub cr)) and Ionization Potential (IP). Because the models we favor are those that produce extended profile wings as observed in high spectral resolution studies, the line width correlations of our favoured models are of particular interest. Line width correlations with n(sub cr) and/or IP result only if the width parameter is more sensitive to extended profile wings than is the Full Width at Half-Maximum (FWHM). Correlations between FWHM and n(sub cr) and/or IP result only after convolving the model profiles with a broad instrumental profile that simulates the lower spectral resolution used in early observational studies. The model in agreement with the greatest number of observational considerations has electron density decreasing outward from n(sub e) approx. equals 10(exp 6)/cu cm to n(sub e) approx. equals 10(exp 2)/cu cm and, due to collisional de-excitation effects in the lowest velocity clouds, it generates broad flat-topped profile peaks in the lines of lowest critical density (e.g., [O II] lambda3727 and [S II] lambda(lambda)6716, 6731). Because the observed profile peaks of both low and high critical density lines are often very similar, our favored model requires a contribution to NLR emission-line spectra from low-velocity, low-density, and low-ionization gas not included in the model NLR.
Till, Andrew T.; Warsa, James S.; Morel, Jim E.
2018-06-15
The thermal radiative transfer (TRT) equations comprise a radiation equation coupled to the material internal energy equation. Linearization of these equations produces effective, thermally-redistributed scattering through absorption-reemission. In this paper, we investigate the effectiveness and efficiency of Linear-Multi-Frequency-Grey (LMFG) acceleration that has been reformulated for use as a preconditioner to Krylov iterative solution methods. We introduce two general frameworks, the scalar flux formulation (SFF) and the absorption rate formulation (ARF), and investigate their iterative properties in the absence and presence of true scattering. SFF has a group-dependent state size but may be formulated without inner iterations in the presence ofmore » scattering, while ARF has a group-independent state size but requires inner iterations when scattering is present. We compare and evaluate the computational cost and efficiency of LMFG applied to these two formulations using a direct solver for the preconditioners. Finally, this work is novel because the use of LMFG for the radiation transport equation, in conjunction with Krylov methods, involves special considerations not required for radiation diffusion.« less
Analysis of drift effects on the tokamak power scrape-off width using SOLPS-ITER
Meier, E. T.; Goldston, R. J.; Kaveeva, E. G.; ...
2016-11-02
SOLPS-ITER, a comprehensive 2D scrape-off layer modeling package, is used to examine the physical mechanisms that set the scrape-off width (more » $${{\\lambda}_{q}}$$ ) for inter-ELM power exhaust. Guided by Goldston's heuristic drift (HD) model, which shows remarkable quantitative agreement with experimental data, this research examines drift effects on $${{\\lambda}_{q}}$$ in a DIII-D H-mode magnetic equilibrium. As a numerical expedient, a low target recycling coefficient of 0.9 is used in the simulations, resulting in outer target plasma that is sheath limited instead of conduction limited as in the experiment. Scrape-off layer (SOL) particle diffusivity (D SOL) is scanned from 1 to 0.1 m2 s –1. Across this diffusivity range, outer divertor heat flux is dominated by a narrow (~3–4mm when mapped to the outer midplane) electron convection channel associated with thermoelectric current through the SOL from outer to inner divertor. An order-unity up–down ion pressure asymmetry allows net ion drift flux across the separatrix, facilitated by an artificial mechanism that mimics the anomalous electron transport required for overall ambipolarity in the HD model. At $${{D}_{\\text{SOL}}}=0.1$$ m2 s –1, the density fall-off length is similar to the electron temperature fall-off length, as predicted by the HD model and as seen experimentally. Furthermore, this research represents a step toward a deeper understanding of the power scrape-off width, and serves as a basis for extending fluid modeling to more experimentally relevant, high-collisionality regimes.« less
Upwind relaxation methods for the Navier-Stokes equations using inner iterations
NASA Technical Reports Server (NTRS)
Taylor, Arthur C., III; Ng, Wing-Fai; Walters, Robert W.
1992-01-01
A subsonic and a supersonic problem are respectively treated by an upwind line-relaxation algorithm for the Navier-Stokes equations using inner iterations to accelerate steady-state solution convergence and thereby minimize CPU time. While the ability of the inner iterative procedure to mimic the quadratic convergence of the direct solver method is attested to in both test problems, some of the nonquadratic inner iterative results are noted to have been more efficient than the quadratic. In the more successful, supersonic test case, inner iteration required only about 65 percent of the line-relaxation method-entailed CPU time.
NASA Astrophysics Data System (ADS)
Eftekhar, Roya; Hu, Hao; Zheng, Yingcai
2018-06-01
Iterative solution process is fundamental in seismic inversions, such as in full-waveform inversions and some inverse scattering methods. However, the convergence could be slow or even divergent depending on the initial model used in the iteration. We propose to apply Shanks transformation (ST for short) to accelerate the convergence of the iterative solution. ST is a local nonlinear transformation, which transforms a series locally into another series with an improved convergence property. ST works by separating the series into a smooth background trend called the secular term versus an oscillatory transient term. ST then accelerates the convergence of the secular term. Since the transformation is local, we do not need to know all the terms in the original series which is very important in the numerical implementation. The ST performance was tested numerically for both the forward Born series and the inverse scattering series (ISS). The ST has been shown to accelerate the convergence in several examples, including three examples of forward modeling using the Born series and two examples of velocity inversion based on a particular type of the ISS. We observe that ST is effective in accelerating the convergence and it can also achieve convergence even for a weakly divergent scattering series. As such, it provides a useful technique to invert for a large-contrast medium perturbation in seismic inversion.
Gravitational Radiation with a Positive Cosmological Constant
NASA Astrophysics Data System (ADS)
Bonga, Beatrice
Gravitational radiation is well-understood in spacetimes that are asymptotically flat. However, our Universe is currently expanding at an accelerated rate, which is best described by including a positive cosmological constant, Lambda, in Einstein's equations. Consequently, no matter how far one recedes from sources generating gravitational waves, spacetime curvature never dies and is not asymptotically flat. This dissertation provides first steps to incorporate Lambda in the study of gravitational radiation by analyzing linearized gravitational waves on a de Sitter background. Since the asymptotic structure of de Sitter is very different from that of Minkowski spacetime, many conceptual and technical difficulties arise. The limit Lambda → 0 can be discontinuous: Although energy carried by gravitational waves is always positive in Minkowski spacetime, it can be arbitrarily negative in de Sitter spacetime. Additionally, many of the standard techniques, including 1/r expansions, are no longer applicable. We generalize Einstein's celebrated quadrupole formula describing the power radiated on a flat background to de Sitter spacetime. Even a tiny Lambda brings in qualitatively new features such as contributions from pressure quadrupole moments. Nonetheless, corrections induced by Lambda are O(√Lambda tc) with tc the characteristic time scale of the source and are negligible for current gravitational wave observatories. We demonstrate this explicitly for a binary system in a circular orbit. Radiative modes are encoded in the transverse-traceless part of the spatial components of a gravitational perturbation. When Lambda = 0, one typically extracts these modes in the wave zone by projecting the gravitational perturbation onto the two-sphere orthogonal to the radial direction. We show that this method for waves emitted by spatially compact sources on Minkowski spacetime generically does not yield the transverse-traceless modes; not even infinitely far away. However, the difference between the transverse-traceless and projected modes is non-dynamical and disappears from all physical observables. When one is interested in 'Coulombic' information not captured by the radiative modes, the projection method does not suffice. This is, for example, important for angular momentum carried by gravitational waves. This result relies on Bondi-type expansions for asymptotically flat spacetimes. Therefore, the projection method is not applicable to de Sitter spacetimes.
A Study of Double-Charm and Charm-Strange Baryons inElectron-Positron Annihilations
DOE Office of Scientific and Technical Information (OSTI.GOV)
Edwards, Adam J.; /SLAC
2007-10-15
In this dissertation I describe a study of double-charm and charm-strange baryons based on data collected with the BABAR Detector at the Stanford Linear Accelerator Center. In this study I search for new baryons and make precise measurements of their properties and decay modes. I seek to verify and expand upon double-charm and charm-strange baryon observations made by other experiments. The BABAR Detector is used to measure subatomic particles that are produced at the PEP-II storage rings. I analyze approximately 300 million e+e- {yields} c{bar c} events in a search for the production of double-charm baryons. I search for themore » double-charm baryons {Xi}{sup +}{sub cc} (containing the quarks ccd) and {Xi}{sup ++}{sub cc} (ccu) in decays to {Lambda}{sup +}{sub c}K{sup -}{pi}{sup +} and {Lambda}{sup +}{sub c}K{sup -}{pi}{sup +}{pi}{sup +}, respectively. No statistically significant signals for their production are found, and upper limits on their production are determined. Statistically significant signals for excited charm-strange baryons are observed with my analysis of approximately 500 million e+e- {yields} c{bar c} events. The charged charm-strange baryons {Xi}{sub c}(2970){sup +}, {Xi}{sub c}(3055){sup +}, {Xi}{sub c}(3123){sup +} are found in decays to {Lambda}{sup +}{sub c}K{sup -}{pi}{sup +}, the same decay mode used in the {Xi}{sup +}{sub cc} search. The neutral charm-strange baryon {Xi}{sub c}(3077){sup 0} is observed in decays to {Lambda}{sup +}{sub c}K{sub 8}{pi}{sup -}. I also search for excited charm-strange baryon decays to {Lambda}{sup +}{sub c}K{sub 8}, {Lambda}{sup +}{sub c}K{sup -}, {Lambda}{sup +}{sub c}K{sub 8}{pi}{sup -}{pi}{sup +}, and {Lambda}{sup +}{sub c}K{sup -}{pi}{sup -}{pi}{sup +}. No significant charm-strange baryon signals a f h these decay modes. For each excited charm-strange baryon state that I observe, I measure its mass, natural width (lifetime), and production rate. The properties of these excited charm-strange baryons and their decay modes provide constraints for phenomenological models of quark interactions through quantum chromodynamics. My discovery of the two new charm-strange baryons {Xi}{sub c}(3055){sup +} and {Xi}{sub c}(3123){sup +} influences our theoretical understanding of charm-strange baryon states.« less
Accelerated quantum control using superadiabatic dynamics in a solid-state lambda system
Zhou, Brian B.; Baksic, Alexandre; Ribeiro, Hugo; ...
2016-11-28
Adiabatic evolutions find widespread utility in applications to quantum state engineering1 , geometric quantum computation2 , and quantum simulation3 . Although offering desirable robustness to experimental imperfections, adiabatic techniques are susceptible to decoherence during their long operation time. A recent strategy termed ‘shortcuts to adiabaticity’ 4–10 (STA) aims to circumvent this trade-off by designing fast dynamics to reproduce the results of infinitely slow, adiabatic processes. Here, as a realization of this strategy, we implement ‘superadiabatic’ transitionless driving11 (SATD) to speed up stimulated Raman adiabatic passage1,12–15 (STIRAP) in a solid-state lambda (Λ) system. Utilizing optical transitions to a dissipative excited statemore » in the nitrogen vacancy (NV) center in diamond, we demonstrate the accelerated performance of different shortcut trajectories for population transfer and for the transfer and initialization of coherent superpositions. We reveal that SATD protocols exhibit robustness to dissipation and experimental uncertainty, and can be optimized when these effects are present. These results motivate STA as a promising tool for controlling open quantum systems comprising individual or hybrid nanomechanical, superconducting, and photonic elements in the solid state12–17.« less
Weak convergence of a projection algorithm for variational inequalities in a Banach space
NASA Astrophysics Data System (ADS)
Iiduka, Hideaki; Takahashi, Wataru
2008-03-01
Let C be a nonempty, closed convex subset of a Banach space E. In this paper, motivated by Alber [Ya.I. Alber, Metric and generalized projection operators in Banach spaces: Properties and applications, in: A.G. Kartsatos (Ed.), Theory and Applications of Nonlinear Operators of Accretive and Monotone Type, in: Lecture Notes Pure Appl. Math., vol. 178, Dekker, New York, 1996, pp. 15-50], we introduce the following iterative scheme for finding a solution of the variational inequality problem for an inverse-strongly-monotone operator A in a Banach space: x1=x[set membership, variant]C andxn+1=[Pi]CJ-1(Jxn-[lambda]nAxn) for every , where [Pi]C is the generalized projection from E onto C, J is the duality mapping from E into E* and {[lambda]n} is a sequence of positive real numbers. Then we show a weak convergence theorem (Theorem 3.1). Finally, using this result, we consider the convex minimization problem, the complementarity problem, and the problem of finding a point u[set membership, variant]E satisfying 0=Au.
Active optics null test system based on a liquid crystal programmable spatial light modulator
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ares, Miguel; Royo, Santiago; Sergievskaya, Irina
2010-11-10
We present an active null test system adapted to test lenses and wavefronts with complex shapes and strong local deformations. This system provides greater flexibility than conventional static null tests that match only a precisely positioned, individual wavefront. The system is based on a cylindrical Shack-Hartmann wavefront sensor, a commercial liquid crystal programmable phase modulator (PPM), which acts as the active null corrector, enabling the compensation of large strokes with high fidelity in a single iteration, and a spatial filter to remove unmodulated light when steep phase changes are compensated. We have evaluated the PPM's phase response at 635 nmmore » and checked its performance by measuring its capability to generate different amounts of defocus aberration, finding root mean squared errors below {lambda}/18 for spherical wavefronts with peak-to-valley heights of up to 78.7{lambda}, which stands as the limit from which diffractive artifacts created by the PPM have been found to be critical under no spatial filtering. Results of a null test for a complex lens (an ophthalmic customized progressive addition lens) are presented and discussed.« less
Convex Accelerated Maximum Entropy Reconstruction
Worley, Bradley
2016-01-01
Maximum entropy (MaxEnt) spectral reconstruction methods provide a powerful framework for spectral estimation of nonuniformly sampled datasets. Many methods exist within this framework, usually defined based on the magnitude of a Lagrange multiplier in the MaxEnt objective function. An algorithm is presented here that utilizes accelerated first-order convex optimization techniques to rapidly and reliably reconstruct nonuniformly sampled NMR datasets using the principle of maximum entropy. This algorithm – called CAMERA for Convex Accelerated Maximum Entropy Reconstruction Algorithm – is a new approach to spectral reconstruction that exhibits fast, tunable convergence in both constant-aim and constant-lambda modes. A high-performance, open source NMR data processing tool is described that implements CAMERA, and brief comparisons to existing reconstruction methods are made on several example spectra. PMID:26894476
NASA Astrophysics Data System (ADS)
Bommier, Véronique
2016-06-01
Context. The spectrum of the linear polarization, which is formed by scattering and observed on the solar disk close to the limb, is very different from the intensity spectrum and thus able to provide new information, in particular about anisotropies in the solar surface plasma and magnetic fields. In addition, a large number of lines show far wing polarization structures assigned to partial redistribution (PRD), which we prefer to denote as Rayleigh/Raman scattering. The two-level or two-term atom approximation without any lower level polarization is insufficient for many lines. Aims: In the previous paper of this series, we presented our theory generalized to the multilevel and multiline atom and comprised of statistical equilibrium equations for the atomic density matrix elements and radiative transfer equation for the polarized radiation. The present paper is devoted to applying this theory to model the second solar spectrum of the Na I D1 and D2 lines. Methods: The solution method is iterative, of the lambda-iteration type. The usual acceleration techniques were considered or even applied, but we found these to be unsuccessful, in particular because of nonlinearity or large number of quantities determining the radiation at each depth. Results: The observed spectrum is qualitatively reproduced in line center, but the convergence is yet to be reached in the far wings and the observed spectrum is not totally reproduced there. Conclusions: We need to investigate noniterative resolution methods. The other limitation lies in the one-dimensional (1D) atmosphere model, which is unable to reproduce the intermittent matter structure formed of small loops or spicules in the chromosphere. This modeling is rough, but the computing time in the presence of hyperfine structure and PRD prevents us from envisaging a three-dimensional (3D) model at this instant.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Errede, Steven Michael
1981-01-01
An experiment was performed in the 350 GeV wide-band neutrino beam at the Fermi National Accelerator Laboratory using a high-precision, high-efficiency hybrid emulsion/neutrino spectrometer, with which the mean lifetimes of the D/sup +/, D/sup 0/, and F/sup +/ mesons and ..lambda../sub c//sup +/ baryon were measured. 1829 neutrino interactions were reconstructed with a vertex within the emulsion fiducial volume, 1242 of which were subsequently found in the emulsion. In 49 of the found neutrino events a charmed particle, produced at the primary vertex, was observed to decay within the emulsion volume. The mean lifetimes of charmed particles were determined frommore » the reconstructed decays of 5 D/sup +/, 15 D/sup 0/, 3 F/sup +/ mesons: and 8 ..lambda../sub c//sup +/ baryons: tau/sub D/sup +// = 10.3/sub -4.2//sup +10.3/ x 10/sup -13/ sec; tau/sub D/sup 0// = 2.3/sub -0.5//sup +0.8/ x 10/sup -13/ sec; tau/sub f/sup +// = 2.0/sub -0.8//sup +1.8/ x 10/sup -13/ sec; and tau/sub ..lambda..//sub c//sup +/ = 2.3/sub -0.6//sup +1.0/ x 10/sup -13/ sec. The charmed particle masses measured in this experiment were: M/sub D/sup +// = 1851 +- 20 MeV/c/sup 2/; M/sub D/sup 0// = 1856 +- 15 MeV/c/sup 2/; M/sub F/sup +// = 2042 +- 33 MeV/c/sup 2/; M/sub ..lambda..//sub c//sup +/ = 2265 +- 30 MeV/c/sub 2/.« less
Nikazad, T; Davidi, R; Herman, G. T.
2013-01-01
We study the convergence of a class of accelerated perturbation-resilient block-iterative projection methods for solving systems of linear equations. We prove convergence to a fixed point of an operator even in the presence of summable perturbations of the iterates, irrespective of the consistency of the linear system. For a consistent system, the limit point is a solution of the system. In the inconsistent case, the symmetric version of our method converges to a weighted least squares solution. Perturbation resilience is utilized to approximate the minimum of a convex functional subject to the equations. A main contribution, as compared to previously published approaches to achieving similar aims, is a more than an order of magnitude speed-up, as demonstrated by applying the methods to problems of image reconstruction from projections. In addition, the accelerated algorithms are illustrated to be better, in a strict sense provided by the method of statistical hypothesis testing, than their unaccelerated versions for the task of detecting small tumors in the brain from X-ray CT projection data. PMID:23440911
Nikazad, T; Davidi, R; Herman, G T
2012-03-01
We study the convergence of a class of accelerated perturbation-resilient block-iterative projection methods for solving systems of linear equations. We prove convergence to a fixed point of an operator even in the presence of summable perturbations of the iterates, irrespective of the consistency of the linear system. For a consistent system, the limit point is a solution of the system. In the inconsistent case, the symmetric version of our method converges to a weighted least squares solution. Perturbation resilience is utilized to approximate the minimum of a convex functional subject to the equations. A main contribution, as compared to previously published approaches to achieving similar aims, is a more than an order of magnitude speed-up, as demonstrated by applying the methods to problems of image reconstruction from projections. In addition, the accelerated algorithms are illustrated to be better, in a strict sense provided by the method of statistical hypothesis testing, than their unaccelerated versions for the task of detecting small tumors in the brain from X-ray CT projection data.
NASA Astrophysics Data System (ADS)
Al-Chalabi, Rifat M. Khalil
1997-09-01
Development of an improvement to the computational efficiency of the existing nested iterative solution strategy of the Nodal Exapansion Method (NEM) nodal based neutron diffusion code NESTLE is presented. The improvement in the solution strategy is the result of developing a multilevel acceleration scheme that does not suffer from the numerical stalling associated with a number of iterative solution methods. The acceleration scheme is based on the multigrid method, which is specifically adapted for incorporation into the NEM nonlinear iterative strategy. This scheme optimizes the computational interplay between the spatial discretization and the NEM nonlinear iterative solution process through the use of the multigrid method. The combination of the NEM nodal method, calculation of the homogenized, neutron nodal balance coefficients (i.e. restriction operator), efficient underlying smoothing algorithm (power method of NESTLE), and the finer mesh reconstruction algorithm (i.e. prolongation operator), all operating on a sequence of coarser spatial nodes, constitutes the multilevel acceleration scheme employed in this research. Two implementations of the multigrid method into the NESTLE code were examined; the Imbedded NEM Strategy and the Imbedded CMFD Strategy. The main difference in implementation between the two methods is that in the Imbedded NEM Strategy, the NEM solution is required at every MG level. Numerical tests have shown that the Imbedded NEM Strategy suffers from divergence at coarse- grid levels, hence all the results for the different benchmarks presented here were obtained using the Imbedded CMFD Strategy. The novelties in the developed MG method are as follows: the formulation of the restriction and prolongation operators, and the selection of the relaxation method. The restriction operator utilizes a variation of the reactor physics, consistent homogenization technique. The prolongation operator is based upon a variant of the pin power reconstruction methodology. The relaxation method, which is the power method, utilizes a constant coefficient matrix within the NEM non-linear iterative strategy. The choice of the MG nesting within the nested iterative strategy enables the incorporation of other non-linear effects with no additional coding effort. In addition, if an eigenvalue problem is being solved, it remains an eigenvalue problem at all grid levels, simplifying coding implementation. The merit of the developed MG method was tested by incorporating it into the NESTLE iterative solver, and employing it to solve four different benchmark problems. In addition to the base cases, three different sensitivity studies are performed, examining the effects of number of MG levels, homogenized coupling coefficients correction (i.e. restriction operator), and fine-mesh reconstruction algorithm (i.e. prolongation operator). The multilevel acceleration scheme developed in this research provides the foundation for developing adaptive multilevel acceleration methods for steady-state and transient NEM nodal neutron diffusion equations. (Abstract shortened by UMI.)
NASA Astrophysics Data System (ADS)
Quan, Haiyang; Wu, Fan; Hou, Xi
2015-10-01
New method for reconstructing rotationally asymmetric surface deviation with pixel-level spatial resolution is proposed. It is based on basic iterative scheme and accelerates the Gauss-Seidel method by introducing an acceleration parameter. This modified Successive Over-relaxation (SOR) is effective for solving the rotationally asymmetric components with pixel-level spatial resolution, without the usage of a fitting procedure. Compared to the Jacobi and Gauss-Seidel method, the modified SOR method with an optimal relaxation factor converges much faster and saves more computational costs and memory space without reducing accuracy. It has been proved by real experimental results.
Xu, Q; Yang, D; Tan, J; Anastasio, M
2012-06-01
To improve image quality and reduce imaging dose in CBCT for radiation therapy applications and to realize near real-time image reconstruction based on use of a fast convergence iterative algorithm and acceleration by multi-GPUs. An iterative image reconstruction that sought to minimize a weighted least squares cost function that employed total variation (TV) regularization was employed to mitigate projection data incompleteness and noise. To achieve rapid 3D image reconstruction (< 1 min), a highly optimized multiple-GPU implementation of the algorithm was developed. The convergence rate and reconstruction accuracy were evaluated using a modified 3D Shepp-Logan digital phantom and a Catphan-600 physical phantom. The reconstructed images were compared with the clinical FDK reconstruction results. Digital phantom studies showed that only 15 iterations and 60 iterations are needed to achieve algorithm convergence for 360-view and 60-view cases, respectively. The RMSE was reduced to 10-4 and 10-2, respectively, by using 15 iterations for each case. Our algorithm required 5.4s to complete one iteration for the 60-view case using one Tesla C2075 GPU. The few-view study indicated that our iterative algorithm has great potential to reduce the imaging dose and preserve good image quality. For the physical Catphan studies, the images obtained from the iterative algorithm possessed better spatial resolution and higher SNRs than those obtained from by use of a clinical FDK reconstruction algorithm. We have developed a fast convergence iterative algorithm for CBCT image reconstruction. The developed algorithm yielded images with better spatial resolution and higher SNR than those produced by a commercial FDK tool. In addition, from the few-view study, the iterative algorithm has shown great potential for significantly reducing imaging dose. We expect that the developed reconstruction approach will facilitate applications including IGART and patient daily CBCT-based treatment localization. © 2012 American Association of Physicists in Medicine.
Acceleration of GPU-based Krylov solvers via data transfer reduction
Anzt, Hartwig; Tomov, Stanimire; Luszczek, Piotr; ...
2015-04-08
Krylov subspace iterative solvers are often the method of choice when solving large sparse linear systems. At the same time, hardware accelerators such as graphics processing units continue to offer significant floating point performance gains for matrix and vector computations through easy-to-use libraries of computational kernels. However, as these libraries are usually composed of a well optimized but limited set of linear algebra operations, applications that use them often fail to reduce certain data communications, and hence fail to leverage the full potential of the accelerator. In this study, we target the acceleration of Krylov subspace iterative methods for graphicsmore » processing units, and in particular the Biconjugate Gradient Stabilized solver that significant improvement can be achieved by reformulating the method to reduce data-communications through application-specific kernels instead of using the generic BLAS kernels, e.g. as provided by NVIDIA’s cuBLAS library, and by designing a graphics processing unit specific sparse matrix-vector product kernel that is able to more efficiently use the graphics processing unit’s computing power. Furthermore, we derive a model estimating the performance improvement, and use experimental data to validate the expected runtime savings. Finally, considering that the derived implementation achieves significantly higher performance, we assert that similar optimizations addressing algorithm structure, as well as sparse matrix-vector, are crucial for the subsequent development of high-performance graphics processing units accelerated Krylov subspace iterative methods.« less
Analytical dose evaluation of neutron and secondary gamma-ray skyshine from nuclear facilities
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hayashi, K.; Nakamura, T.
1985-11-01
The skyshine dose distributions of neutron and secondary gamma rays were calculated systematically using the Monte Carlo method for distances up to 2 km from the source. The energy of source neutrons ranged from thermal to 400 MeV; their emission angle from 0 to 90 deg from the ver tical was treated with a distribution of the direction cosine containing five equal intervals. Calculated dose distributions D(r) were fitted to the formula; D(r) = Q exp (-r/lambda)/r. The value of Q and lambda are slowly varied functions of energy. This formula was applied to the benchmark problems of neutron skyshinemore » from fission, fusion, and accelerator facilities, and good agreement was achieved. This formula will be quite useful for shielding designs of various nuclear facilities.« less
High resolution spectroscopy of the 12Lambda B hypernucleus produced by the (e,e'K+) reaction.
Miyoshi, T; Sarsour, M; Yuan, L; Zhu, X; Ahmidouch, A; Ambrozewicz, P; Androic, D; Angelescu, T; Asaturyan, R; Avery, S; Baker, O K; Bertovic, I; Breuer, H; Carlini, R; Cha, J; Chrien, R; Christy, M; Cole, L; Danagoulian, S; Dehnhard, D; Elaasar, M; Empl, A; Ent, R; Fenker, H; Fujii, Y; Furic, M; Gan, L; Garrow, K; Gasparian, A; Gueye, P; Harvey, M; Hashimoto, O; Hinton, W; Hu, B; Hungerford, E; Jackson, C; Johnston, K; Juengst, H; Keppel, C; Lan, K; Liang, Y; Likhachev, V P; Liu, J H; Mack, D; Margaryan, A; Markowitz, P; Martoff, J; Mkrtchyan, H; Nakamura, S N; Petkovic, T; Reinhold, J; Roche, J; Sato, Y; Sawafta, R; Simicevic, N; Smith, G; Stepanyan, S; Tadevosyan, V; Takahashi, T; Tanida, K; Tang, L; Ukai, M; Uzzle, A; Vulcan, W; Wells, S; Wood, S; Xu, G; Yamaguchi, H; Yan, C
2003-06-13
High-energy, cw electron beams at new accelerator facilities allow electromagnetic production and precision study of hypernuclear structure, and we report here on the first experiment demonstrating the potential of the (e,e'K+) reaction for hypernuclear spectroscopy. This experiment is also the first to take advantage of the enhanced virtual photon flux available when electrons are scattered at approximately zero degrees. The observed energy resolution was found to be approximately 900 keV for the (12)(Lambda)B spectrum, and is substantially better than any previous hypernuclear experiment using magnetic spectrometers. The positions of the major excitations are found to be in agreement with a theoretical prediction and with a previous binding energy measurement, but additional structure is also observed in the core excited region, underlining the future promise of this technique.
Power Transmission From The ITER Model Negative Ion Source
DOE Office of Scientific and Technical Information (OSTI.GOV)
Boilson, D.; Esch, H. P. L. de; Grand, C.
2007-08-10
In Cadarache development on negative ion sources is being carried out on the KAMABOKO III ion source on the MANTIS test bed. This is a model of the ion source designed for the neutral beam injectors of ITER. This ion source has been developed in collaboration with JAERI, Japan, who also designed and supplied the ion source. Its target performance is to accelerate a D- beam, with a current density of 200 A/m2 and <1 electron extracted per accelerated D- ion, at a source filling pressure of 0.3 Pa. For ITER a continuous ion beam must be assured for pulsemore » lengths of 1000 s, but beams of up to 3,600 s are also envisaged. The ion source is attached to a 3 grid 30 keV accelerator (also supplied by JAERI) and the accelerated negative ion current is determined from the energy deposited on a calorimeter. During long pulse operation ({<=}1000 s) it was found that the current density of both D- and H- beams, measured at the calorimeter was lower than expected and that a large discrepancy existed between the accelerated currents measured electrically and those transmitted to the calorimeter. The possibility that this discrepancy arose because the accelerated current included electrons (which would not be able to reach the calorimeter) was investigated and subsequently eliminated. Further studies have shown that the fraction of the electrical current reaching the calorimeter varies with the pulse length, which led to the suggestion that one or more of the accelerator grids were distorting due to the incident power during operation, leading to a progressive deterioration in the beam quality.. New extraction and acceleration grids have been designed and installed, which should have a better tolerance to thermal loads than those previously used. This paper describes the measurements of the power transmission and distribution using these grids.« less
NASA Astrophysics Data System (ADS)
Shao, Meiyue; Aktulga, H. Metin; Yang, Chao; Ng, Esmond G.; Maris, Pieter; Vary, James P.
2018-01-01
We describe a number of recently developed techniques for improving the performance of large-scale nuclear configuration interaction calculations on high performance parallel computers. We show the benefit of using a preconditioned block iterative method to replace the Lanczos algorithm that has traditionally been used to perform this type of computation. The rapid convergence of the block iterative method is achieved by a proper choice of starting guesses of the eigenvectors and the construction of an effective preconditioner. These acceleration techniques take advantage of special structure of the nuclear configuration interaction problem which we discuss in detail. The use of a block method also allows us to improve the concurrency of the computation, and take advantage of the memory hierarchy of modern microprocessors to increase the arithmetic intensity of the computation relative to data movement. We also discuss the implementation details that are critical to achieving high performance on massively parallel multi-core supercomputers, and demonstrate that the new block iterative solver is two to three times faster than the Lanczos based algorithm for problems of moderate sizes on a Cray XC30 system.
Status of the Negative Ion Based Heating and Diagnostic Neutral Beams for ITER
NASA Astrophysics Data System (ADS)
Schunke, B.; Bora, D.; Hemsworth, R.; Tanga, A.
2009-03-01
The current baseline of ITER foresees 2 Heating Neutral Beam (HNB's) systems based on negative ion technology, each accelerating to 1 MeV 40 A of D- and capable of delivering 16.5 MW of D0 to the ITER plasma, with a 3rd HNB injector foreseen as an upgrade option [1]. In addition a dedicated Diagnostic Neutral Beam (DNB) accelerating 60 A of H- to 100 keV will inject ≈15 A equivalent of H0 for charge exchange recombination spectroscopy and other diagnostics. Recently the RF driven negative ion source developed by IPP Garching has replaced the filamented ion source as the reference ITER design. The RF source developed at IPP, which is approximately a quarter scale of the source needed for ITER, is expected to have reduced caesium consumption compared to the filamented arc driven ion source. The RF driven source has demonstrated adequate accelerated D- and H- current densities as well as long-pulse operation [2, 3]. It is foreseen that the HNB's and the DNB will use the same negative ion source. Experiments with a half ITER-size ion source are on-going at IPP and the operation of a full-scale ion source will be demonstrated, at full power and pulse length, in the dedicated Ion Source Test Bed (ISTF), which will be part of the Neutral Beam Test Facility (NBTF), in Padua, Italy. This facility will carry out the necessary R&D for the HNB's for ITER and demonstrate operation of the full-scale HNB beamline. An overview of the current status of the neutral beam (NB) systems and the chosen configuration will be given and the ongoing integration effort into the ITER plant will be highlighted. It will be demonstrated how installation and maintenance logistics have influenced the design, notably the top access scheme facilitating access for maintenance and installation. The impact of the ITER Design Review and recent design change requests (DCRs) will be briefly discussed, including start-up and commissioning issues. The low current hydrogen phase now envisaged for start-up imposed specific requirements for operating the HNB's at full beam power. It has been decided to address the shinethrough issue by installing wall armour protection, which increases the operational space in all scenarios. Other NB related issues identified by the Design Review process will be discussed and the possible changes to the ITER baseline indicated.
Status of the Negative Ion Based Heating and Diagnostic Neutral Beams for ITER
DOE Office of Scientific and Technical Information (OSTI.GOV)
Schunke, B.; Bora, D.; Hemsworth, R.
2009-03-12
The current baseline of ITER foresees 2 Heating Neutral Beam (HNB's) systems based on negative ion technology, each accelerating to 1 MeV 40 A of D{sup -} and capable of delivering 16.5 MW of D{sup 0} to the ITER plasma, with a 3rd HNB injector foreseen as an upgrade option. In addition a dedicated Diagnostic Neutral Beam (DNB) accelerating 60 A of H{sup -} to 100 keV will inject {approx_equal}15 A equivalent of H{sup 0} for charge exchange recombination spectroscopy and other diagnostics. Recently the RF driven negative ion source developed by IPP Garching has replaced the filamented ion sourcemore » as the reference ITER design. The RF source developed at IPP, which is approximately a quarter scale of the source needed for ITER, is expected to have reduced caesium consumption compared to the filamented arc driven ion source. The RF driven source has demonstrated adequate accelerated D{sup -} and H{sup -} current densities as well as long-pulse operation. It is foreseen that the HNB's and the DNB will use the same negative ion source. Experiments with a half ITER-size ion source are on-going at IPP and the operation of a full-scale ion source will be demonstrated, at full power and pulse length, in the dedicated Ion Source Test Bed (ISTF), which will be part of the Neutral Beam Test Facility (NBTF), in Padua, Italy. This facility will carry out the necessary R and D for the HNB's for ITER and demonstrate operation of the full-scale HNB beamline. An overview of the current status of the neutral beam (NB) systems and the chosen configuration will be given and the ongoing integration effort into the ITER plant will be highlighted. It will be demonstrated how installation and maintenance logistics have influenced the design, notably the top access scheme facilitating access for maintenance and installation. The impact of the ITER Design Review and recent design change requests (DCRs) will be briefly discussed, including start-up and commissioning issues. The low current hydrogen phase now envisaged for start-up imposed specific requirements for operating the HNB's at full beam power. It has been decided to address the shinethrough issue by installing wall armour protection, which increases the operational space in all scenarios. Other NB related issues identified by the Design Review process will be discussed and the possible changes to the ITER baseline indicated.« less
Zhao, Tuo; Liu, Han
2016-01-01
We propose an accelerated path-following iterative shrinkage thresholding algorithm (APISTA) for solving high dimensional sparse nonconvex learning problems. The main difference between APISTA and the path-following iterative shrinkage thresholding algorithm (PISTA) is that APISTA exploits an additional coordinate descent subroutine to boost the computational performance. Such a modification, though simple, has profound impact: APISTA not only enjoys the same theoretical guarantee as that of PISTA, i.e., APISTA attains a linear rate of convergence to a unique sparse local optimum with good statistical properties, but also significantly outperforms PISTA in empirical benchmarks. As an application, we apply APISTA to solve a family of nonconvex optimization problems motivated by estimating sparse semiparametric graphical models. APISTA allows us to obtain new statistical recovery results which do not exist in the existing literature. Thorough numerical results are provided to back up our theory. PMID:28133430
Twin-Screw Extruder and Pellet Accelerator Integration Developments for ITER
DOE Office of Scientific and Technical Information (OSTI.GOV)
Meitner, Steven J; Baylor, Larry R; Combs, Stephen Kirk
The ITER pellet injection system consisting of a twinscrew frozen hydrogen isotope extruder, coupled to a combination solenoid actuated pellet cutter and pneumatic pellet accelerator, is under development at the Oak Ridge National Laboratory. A prototype extruder has been built to produce a continuous solid deuterium extrusion and will be integrated with a secondary section, where pellets are cut, chambered, and launched with a single-stage pneumatic accelerator into the plasma through a guide tube. This integrated pellet injection system is designed to provide 5 mm fueling pellets, injected at a rate up to 10 Hz, or 3 mm edge localizedmore » mode (ELM) triggering pellets, injected at higher rates up to 20 Hz. The pellet cutter, chamber mechanism, and the solenoid operated pneumatic valve for the accelerator are optimized to provide pellet velocities between 200-300 m/s to ensure high pellet survivability while traversing the inner wall fueling guide tubes, and outer wall ELMpacing guide tubes. This paper outlines the current twin-screwextruder design, pellet accelerator design, and the integrationrequired for both fueling and ELM pacing pellets.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Jing Yanfei, E-mail: yanfeijing@uestc.edu.c; Huang Tingzhu, E-mail: tzhuang@uestc.edu.c; Duan Yong, E-mail: duanyong@yahoo.c
This study is mainly focused on iterative solutions with simple diagonal preconditioning to two complex-valued nonsymmetric systems of linear equations arising from a computational chemistry model problem proposed by Sherry Li of NERSC. Numerical experiments show the feasibility of iterative methods to some extent when applied to the problems and reveal the competitiveness of our recently proposed Lanczos biconjugate A-orthonormalization methods to other classic and popular iterative methods. By the way, experiment results also indicate that application specific preconditioners may be mandatory and required for accelerating convergence.
An overview of NSPCG: A nonsymmetric preconditioned conjugate gradient package
NASA Astrophysics Data System (ADS)
Oppe, Thomas C.; Joubert, Wayne D.; Kincaid, David R.
1989-05-01
The most recent research-oriented software package developed as part of the ITPACK Project is called "NSPCG" since it contains many nonsymmetric preconditioned conjugate gradient procedures. It is designed to solve large sparse systems of linear algebraic equations by a variety of different iterative methods. One of the main purposes for the development of the package is to provide a common modular structure for research on iterative methods for nonsymmetric matrices. Another purpose for the development of the package is to investigate the suitability of several iterative methods for vector computers. Since the vectorizability of an iterative method depends greatly on the matrix structure, NSPCG allows great flexibility in the operator representation. The coefficient matrix can be passed in one of several different matrix data storage schemes. These sparse data formats allow matrices with a wide range of structures from highly structured ones such as those with all nonzeros along a relatively small number of diagonals to completely unstructured sparse matrices. Alternatively, the package allows the user to call the accelerators directly with user-supplied routines for performing certain matrix operations. In this case, one can use the data format from an application program and not be required to copy the matrix into one of the package formats. This is particularly advantageous when memory space is limited. Some of the basic preconditioners that are available are point methods such as Jacobi, Incomplete LU Decomposition and Symmetric Successive Overrelaxation as well as block and multicolor preconditioners. The user can select from a large collection of accelerators such as Conjugate Gradient (CG), Chebyshev (SI, for semi-iterative), Generalized Minimal Residual (GMRES), Biconjugate Gradient Squared (BCGS) and many others. The package is modular so that almost any accelerator can be used with almost any preconditioner.
The use of Lanczos's method to solve the large generalized symmetric definite eigenvalue problem
NASA Technical Reports Server (NTRS)
Jones, Mark T.; Patrick, Merrell L.
1989-01-01
The generalized eigenvalue problem, Kx = Lambda Mx, is of significant practical importance, especially in structural enginering where it arises as the vibration and buckling problem. A new algorithm, LANZ, based on Lanczos's method is developed. LANZ uses a technique called dynamic shifting to improve the efficiency and reliability of the Lanczos algorithm. A new algorithm for solving the tridiagonal matrices that arise when using Lanczos's method is described. A modification of Parlett and Scott's selective orthogonalization algorithm is proposed. Results from an implementation of LANZ on a Convex C-220 show it to be superior to a subspace iteration code.
Huang, Hsuan-Ming; Hsiao, Ing-Tsung
2016-01-01
In recent years, there has been increased interest in low-dose X-ray cone beam computed tomography (CBCT) in many fields, including dentistry, guided radiotherapy and small animal imaging. Despite reducing the radiation dose, low-dose CBCT has not gained widespread acceptance in routine clinical practice. In addition to performing more evaluation studies, developing a fast and high-quality reconstruction algorithm is required. In this work, we propose an iterative reconstruction method that accelerates ordered-subsets (OS) reconstruction using a power factor. Furthermore, we combine it with the total-variation (TV) minimization method. Both simulation and phantom studies were conducted to evaluate the performance of the proposed method. Results show that the proposed method can accelerate conventional OS methods, greatly increase the convergence speed in early iterations. Moreover, applying the TV minimization to the power acceleration scheme can further improve the image quality while preserving the fast convergence rate.
Huang, Hsuan-Ming; Hsiao, Ing-Tsung
2016-01-01
In recent years, there has been increased interest in low-dose X-ray cone beam computed tomography (CBCT) in many fields, including dentistry, guided radiotherapy and small animal imaging. Despite reducing the radiation dose, low-dose CBCT has not gained widespread acceptance in routine clinical practice. In addition to performing more evaluation studies, developing a fast and high-quality reconstruction algorithm is required. In this work, we propose an iterative reconstruction method that accelerates ordered-subsets (OS) reconstruction using a power factor. Furthermore, we combine it with the total-variation (TV) minimization method. Both simulation and phantom studies were conducted to evaluate the performance of the proposed method. Results show that the proposed method can accelerate conventional OS methods, greatly increase the convergence speed in early iterations. Moreover, applying the TV minimization to the power acceleration scheme can further improve the image quality while preserving the fast convergence rate. PMID:27073853
Wu, Tongbo; Yang, Yufei; Chen, Wei; Wang, Jiayu; Yang, Ziyu; Wang, Shenlin; Xiao, Xianjin; Li, Mengyuan; Zhao, Meiping
2018-04-06
Lambda exonuclease (λ exo) plays an important role in the resection of DNA ends for DNA repair. Currently, it is also a widely used enzymatic tool in genetic engineering, DNA-binding protein mapping, nanopore sequencing and biosensing. Herein, we disclose two noncanonical properties of this enzyme and suggest a previously undescribed hydrophobic interaction model between λ exo and DNA substrates. We demonstrate that the length of the free portion of the substrate strand in the dsDNA plays an essential role in the initiation of digestion reactions by λ exo. A dsDNA with a 5' non-phosphorylated, two-nucleotide-protruding end can be digested by λ exo with very high efficiency. Moreover, we show that when a conjugated structure is covalently attached to an internal base of the dsDNA, the presence of a single mismatched base pair at the 5' side of the modified base may significantly accelerate the process of digestion by λ exo. A detailed comparison study revealed additional π-π stacking interactions between the attached label and the amino acid residues of the enzyme. These new findings not only broaden our knowledge of the enzyme but will also be very useful for research on DNA repair and in vitro processing of nucleic acids.
NEWTPOIS- NEWTON POISSON DISTRIBUTION PROGRAM
NASA Technical Reports Server (NTRS)
Bowerman, P. N.
1994-01-01
The cumulative poisson distribution program, NEWTPOIS, is one of two programs which make calculations involving cumulative poisson distributions. Both programs, NEWTPOIS (NPO-17715) and CUMPOIS (NPO-17714), can be used independently of one another. NEWTPOIS determines percentiles for gamma distributions with integer shape parameters and calculates percentiles for chi-square distributions with even degrees of freedom. It can be used by statisticians and others concerned with probabilities of independent events occurring over specific units of time, area, or volume. NEWTPOIS determines the Poisson parameter (lambda), that is; the mean (or expected) number of events occurring in a given unit of time, area, or space. Given that the user already knows the cumulative probability for a specific number of occurrences (n) it is usually a simple matter of substitution into the Poisson distribution summation to arrive at lambda. However, direct calculation of the Poisson parameter becomes difficult for small positive values of n and unmanageable for large values. NEWTPOIS uses Newton's iteration method to extract lambda from the initial value condition of the Poisson distribution where n=0, taking successive estimations until some user specified error term (epsilon) is reached. The NEWTPOIS program is written in C. It was developed on an IBM AT with a numeric co-processor using Microsoft C 5.0. Because the source code is written using standard C structures and functions, it should compile correctly on most C compilers. The program format is interactive, accepting epsilon, n, and the cumulative probability of the occurrence of n as inputs. It has been implemented under DOS 3.2 and has a memory requirement of 30K. NEWTPOIS was developed in 1988.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Huber, A.; Brezinsek, S.; Mertens, Ph.
2012-10-15
A new endoscope with optimised divertor view has been developed in order to survey and monitor the emission of specific impurities such as tungsten and the remaining carbon as well as beryllium in the tungsten divertor of JET after the implementation of the ITER-like wall in 2011. The endoscope is a prototype for testing an ITER relevant design concept based on reflective optics only. It may be subject to high neutron fluxes as expected in ITER. The operating wavelength range, from 390 nm to 2500 nm, allows the measurements of the emission of all expected impurities (W I, Be II,more » C I, C II, C III) with high optical transmittance ({>=}30% in the designed wavelength range) as well as high spatial resolution that is {<=}2 mm at the object plane and {<=}3 mm for the full depth of field ({+-}0.7 m). The new optical design includes options for in situ calibration of the endoscope transmittance during the experimental campaign, which allows the continuous tracing of possible transmittance degradation with time due to impurity deposition and erosion by fast neutral particles. In parallel to the new optical design, a new type of possibly ITER relevant shutter system based on pneumatic techniques has been developed and integrated into the endoscope head. The endoscope is equipped with four digital CCD cameras, each combined with two filter wheels for narrow band interference and neutral density filters. Additionally, two protection cameras in the {lambda} > 0.95 {mu}m range have been integrated in the optical design for the real time wall protection during the plasma operation of JET.« less
Nested Conjugate Gradient Algorithm with Nested Preconditioning for Non-linear Image Restoration.
Skariah, Deepak G; Arigovindan, Muthuvel
2017-06-19
We develop a novel optimization algorithm, which we call Nested Non-Linear Conjugate Gradient algorithm (NNCG), for image restoration based on quadratic data fitting and smooth non-quadratic regularization. The algorithm is constructed as a nesting of two conjugate gradient (CG) iterations. The outer iteration is constructed as a preconditioned non-linear CG algorithm; the preconditioning is performed by the inner CG iteration that is linear. The inner CG iteration, which performs preconditioning for outer CG iteration, itself is accelerated by an another FFT based non-iterative preconditioner. We prove that the method converges to a stationary point for both convex and non-convex regularization functionals. We demonstrate experimentally that proposed method outperforms the well-known majorization-minimization method used for convex regularization, and a non-convex inertial-proximal method for non-convex regularization functional.
NASA Technical Reports Server (NTRS)
Jameson, A.
1975-01-01
The use of a fast elliptic solver in combination with relaxation is presented as an effective way to accelerate the convergence of transonic flow calculations, particularly when a marching scheme can be used to treat the supersonic zone in the relaxation process.
Neutrino Mass Bounds from 0{nu}{beta}{beta} Decays and Large Scale Structures
DOE Office of Scientific and Technical Information (OSTI.GOV)
Keum, Y.-Y.; Department of Physics, National Taiwan University, Taipei, Taiwan 10672; Ichiki, K.
2008-05-21
We investigate the way how the total mass sum of neutrinos can be constrained from the neutrinoless double beta decay and cosmological probes with cosmic microwave background (WMAP 3-year results), large scale structures including 2dFGRS and SDSS data sets. First we discuss, in brief, on the current status of neutrino mass bounds from neutrino beta decays and cosmic constrain within the flat {lambda}CMD model. In addition, we explore the interacting neutrino dark-energy model, where the evolution of neutrino masses is determined by quintessence scalar filed, which is responsable for cosmic acceleration today. Assuming the flatness of the universe, the constraintmore » we can derive from the current observation is {sigma}m{sub {nu}}<0.87 eV at the 95% confidence level, which is consistent with {sigma}m{sub {nu}}<0.68 eV in the flat {lambda}CDM model.« less
Analysis of the velocity law in the wind of the Be star Lambda Pavonis
NASA Technical Reports Server (NTRS)
Chen, Haiqi; Ringuelet, Adela; Sahade, Jorge; Kondo, Yoji
1989-01-01
This paper reanalyzes the IUE spectra of Lambda Pavonis secured in 1982 (Sahade et al.). It is found that the profiles of the broad UV lines are either rotationally broadened or nonrotationally broadened and that the rotationally broadened profiles can be sorted out in two groups characterized by rotational velocity values of 170 km/s and of 210 km/s, respectively. From the analysis of the rotational and of the radial velocities it is possible to distinguish two regions in the extended atmosphere of the star, namely, a region which is rotating and a region which is expanding. In the rotating region, the radial velocities are about zero, and the rotational velocity increases from 170 km/s to 250 km/s. In the expanding region, the rotational energy dissipates, the wind is accelerated to a maximum of -155 km/s, and farther out it decelerates.
A Radiative Transfer Simulation of Water Rotational Excitation in Comets
NASA Astrophysics Data System (ADS)
Zakharov, V.; Biver, N.; Bockelee-Morvan, D.; Crovisier, J.; Lecacheux, A.
2005-08-01
In order to interpret comet observations of the 557 GHz water line performed with the Odin satellite (e.g., Lecacheux et al. 2003, A&A, 402, 55), we have developed a numerical model for the simulation of optically thick water rotational emission in cometary coma. For the treatment of radiative transfer, we have elaborated a Monte Carlo code based on the accelerated lambda iteration algorithm presented in Hogerheijde and van der Tak (2000, A&A, 362, 697). The model assumes a spherically symmetric density distribution with constant expansion velocity. It includes the seven lowest rotational levels of ortho-water, which are the primarily populated levels in the rotationally cold gas of the coma. Collisions with water and electrons, and infrared pumping, are taken into account. The model is similar to that presented by Bensch and Bergin (2004, ApJ, 615, 531). We compared the results obtained with this new model with those obtained by the model of Bockelee-Morvan (1987, A&A, 181, 169). Bockelee-Morvan used the escape probability formalism to treat radiation trapping, which is in principle only valid for large velocity gradients. Surprisingly, the results of both models differ only by a few percent, showing that the escape probability formalism can be used with good confidence to treat rotational excitation in cometary atmospheres. This model will allow us to prepare future observations by the ESA Herschel Space Observatory. V.Zakharov acknowledges financial support from CNES.
On the synthesis of resonance lines in dynamical models of structured hot-star winds
NASA Technical Reports Server (NTRS)
Puls, J.; Owocki, S. P.; Fullerton, A. W.
1993-01-01
We examine basic issues involved in synthesizing resonance-line profiles from 1-D, dynamical models of highly structured hot-star winds. Although these models exhibit extensive variations in density as well as velocity, the density scale length is still typically much greater than the Sobolev length. The line transfer is thus treated using a Sobolev approach, as generalized by Rybicki & Hummer (1978) to take proper account of the multiple Sobolev resonances arising from the nonmonotonic velocity field. The resulting reduced-lambda-matrix equation describing nonlocal coupling of the source function is solved by iteration, and line profiles are then derived from formal solution integration using this source function. Two more approximate methods that instead use either a stationary or a structured, local source function yield qualitatively similar line-profiles, but are found to violate photon conservation by 10% or more. The full results suggest that such models may indeed be able to reproduce naturally some of the qualitative properties long noted in observed UV line profiles, such as discrete absorption components in unsaturated lines, or the blue-edge variability in saturated lines. However, these particular models do not yet produce the black absorption troughs commonly observed in saturated lines, and it seems that this and other important discrepancies (e.g., in acceleration time scale of absorption components) may require development of more complete models that include rotation and other 2-D and/or 3-D effects.
Fluctuations at the blue edge of saturated wind lines in IUE spectra of O-type stars
NASA Technical Reports Server (NTRS)
Owocki, Stanley P.; Fullerton, Alex
1993-01-01
We examine basic issues involved in synthesizing resonance-line profiles from 1-D, dynamical models of highly structured hot-star winds. Although these models exhibit extensive variations in density as well as velocity, the density scale length is still typically much greater than the Sobolev length. The line transfer is thus treated using a Sobolev approach, as generalized by Rybicki & Hummer (1978) to take proper account of the multiple Sobolev resonances arising from the nonmonotonic velocity field. The resulting reduced-Lambda-matrix equation describing nonlocal coupling of the source function is solved by iteration, and line profiles and then derived from formal solution integration using this source function. The more appropriate methods that instead use either a stationary or a structured, local source function yield qualitatively similar line-profiles, but are found to violate photon conservation by 10 percent or more. The full results suggest that such models may indeed be able to reproduce naturally some of the qualitative properties long noted in observed UV line profiles, such as discrete absorption components in unsaturated lines, or the blue-edge variability in saturated lines. However, these particular models do not yet produce the black absorption troughs commonly observed in saturated lines, and it seems that this and other important discrepancies (e.g., in acceleration time scale of absorption components) may require development of more complete models that include rotation and other 2-D and/or 3-D effects.
Five-Body Cluster Structure of the Double-{Lambda} Hypernucleus {sub {Lambda}{Lambda}}{sup 11}Be
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hiyama, E.; Kamimura, M.; Yamamoto, Y.
2010-05-28
Energy levels of the double {Lambda} hypernucleus, {sub {Lambda}{Lambda}}{sup 11}Be are calculated within the framework of a {alpha}{alpha}n{Lambda}{Lambda} five-body model. Interactions between constituent particles are determined so as to reproduce reasonably the observed low-energy properties of the {alpha}{alpha}, {alpha}{alpha}n nuclei and the existing data for {Lambda}-binding energies of the {alpha}{Lambda}, {alpha}{alpha}{Lambda}, {alpha}n{Lambda}, and {alpha}{alpha}n{Lambda} systems. An effective {Lambda}{Lambda} interaction is constructed so as to reproduce, within the {alpha}{Lambda}{Lambda} three-body model, the B{sub {Lambda}{Lambda}}of {sub {Lambda}{Lambda}}{sup 6}He, which was extracted from the emulsion experiment, the NAGARA event. With no adjustable parameters for the {alpha}{alpha}n{Lambda}{Lambda} system, B{sub {Lambda}{Lambda}}of the ground and boundmore » excited states of {sub {Lambda}{Lambda}}{sup 11}Be are calculated with the Gaussian expansion method. The Hida event, recently observed at KEK-E373 experiment, is interpreted as an observation of the ground state of the {sub {Lambda}{Lambda}}{sup 11}Be.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kang Xianwei; Department of Physics, Henan Normal University, Xinxiang 453007; Li Haibo
2010-03-01
We discuss the possibility of searching for the {Lambda}-{Lambda} oscillations for coherent {Lambda}{Lambda} production in the J/{psi}{yields}{Lambda}{Lambda} decay process. The sensitivity of measurement of {Lambda}-{Lambda} oscillation in the external field at BES-III experiment is considered. These considerations indicate an alternative way to probe the {Delta}B=2 amplitude in addition to neutron oscillation experiments. Both coherent and time-dependent information can be used to extract the {Lambda}-{Lambda} oscillation parameter. With one year's luminosity at BES-III, we can set an upper limit of {delta}m{sub {Lambda}{Lambda}<}10{sup -15} MeV at 90% confidence level, corresponding to about 10{sup -6} s of {Lambda}-{Lambda} oscillation time.
Shao, Meiyue; Aktulga, H. Metin; Yang, Chao; ...
2017-09-14
In this paper, we describe a number of recently developed techniques for improving the performance of large-scale nuclear configuration interaction calculations on high performance parallel computers. We show the benefit of using a preconditioned block iterative method to replace the Lanczos algorithm that has traditionally been used to perform this type of computation. The rapid convergence of the block iterative method is achieved by a proper choice of starting guesses of the eigenvectors and the construction of an effective preconditioner. These acceleration techniques take advantage of special structure of the nuclear configuration interaction problem which we discuss in detail. Themore » use of a block method also allows us to improve the concurrency of the computation, and take advantage of the memory hierarchy of modern microprocessors to increase the arithmetic intensity of the computation relative to data movement. Finally, we also discuss the implementation details that are critical to achieving high performance on massively parallel multi-core supercomputers, and demonstrate that the new block iterative solver is two to three times faster than the Lanczos based algorithm for problems of moderate sizes on a Cray XC30 system.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Shao, Meiyue; Aktulga, H. Metin; Yang, Chao
In this paper, we describe a number of recently developed techniques for improving the performance of large-scale nuclear configuration interaction calculations on high performance parallel computers. We show the benefit of using a preconditioned block iterative method to replace the Lanczos algorithm that has traditionally been used to perform this type of computation. The rapid convergence of the block iterative method is achieved by a proper choice of starting guesses of the eigenvectors and the construction of an effective preconditioner. These acceleration techniques take advantage of special structure of the nuclear configuration interaction problem which we discuss in detail. Themore » use of a block method also allows us to improve the concurrency of the computation, and take advantage of the memory hierarchy of modern microprocessors to increase the arithmetic intensity of the computation relative to data movement. Finally, we also discuss the implementation details that are critical to achieving high performance on massively parallel multi-core supercomputers, and demonstrate that the new block iterative solver is two to three times faster than the Lanczos based algorithm for problems of moderate sizes on a Cray XC30 system.« less
Design of a -1 MV dc UHV power supply for ITER NBI
NASA Astrophysics Data System (ADS)
Watanabe, K.; Yamamoto, M.; Takemoto, J.; Yamashita, Y.; Dairaku, M.; Kashiwagi, M.; Taniguchi, M.; Tobari, H.; Umeda, N.; Sakamoto, K.; Inoue, T.
2009-05-01
Procurement of a dc -1 MV power supply system for the ITER neutral beam injector (NBI) is shared by Japan and the EU. The Japan Atomic Energy Agency as the Japan Domestic Agency (JADA) for ITER contributes to the procurement of dc -1 MV ultra-high voltage (UHV) components such as a dc -1 MV generator, a transmission line and a -1 MV insulating transformer for the ITER NBI power supply. The inverter frequency of 150 Hz in the -1 MV power supply and major circuit parameters have been proposed and adopted in the ITER NBI. The dc UHV insulation has been carefully designed since dc long pulse insulation is quite different from conventional ac insulation or dc short pulse systems. A multi-layer insulation structure of the transformer for a long pulse up to 3600 s has been designed with electric field simulation. Based on the simulation the overall dimensions of the dc UHV components have been finalized. A surge energy suppression system is also essential to protect the accelerator from electric breakdowns. The JADA contributes to provide an effective surge suppression system composed of core snubbers and resistors. Input energy into the accelerator from the power supply can be reduced to about 20 J, which satisfies the design criteria of 50 J in total in the case of breakdown at -1 MV.
The Cadarache negative ion experiments
DOE Office of Scientific and Technical Information (OSTI.GOV)
Massmann, P.; Bottereau, J.M.; Belchenko, Y.
1995-12-31
Up to energies of 140 keV neutral beam injection (NBI) based on positive ions has proven to be a reliable and flexible plasma heating method and has provided major contributions to most of the important experiments on virtually all large tokamaks around the world. As a candidate for additional heating and current drive on next step fusion machines (ITER ao) it is hoped that NBI can be equally successful. The ITER NBI parameters of 1 MeV, 50 MW D{degree} demand primary D{sup {minus}} beams with current densities of at least 15 mA/cm{sup 2}. Although considerable progress has been made inmore » the area of negative ion production and acceleration the high demands still require substantial and urgent development. Regarding negative ion production Cs seeded plasma sources lead the way. Adding a small amount of Cs to the discharge (Cs seeding) not only increases the negative ion yield by a factor 3--5 but also has the advantage that the discharge can be run at lower pressures. This is beneficial for the reduction of stripping losses in the accelerator. Multi-ampere negative ion production in a large plasma source is studied in the MANTIS experiment. Acceleration and neutralization at ITER relevant parameters is the objective of the 1 MV SINGAP experiment.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Liang Nan; Wu Puxun; Zhang Shuangnan
2010-04-15
Gamma-ray bursts (GRBs) have been regarded as standard candles at very high redshift for cosmology research. We have proposed a new method to calibrate GRB distance indicators with Type Ia supernova (SNe Ia) data in a completely cosmology-independent way to avoid the circularity problem that had limited the direct use of GRBs to probe cosmology [N. Liang, W. K. Xiao, Y. Liu, and S. N. Zhang, Astrophys. J. 685, 354 (2008).]. In this paper, a simple method is provided to combine GRB data into the joint observational data analysis to constrain cosmological models; in this method those SNe Ia datamore » points used for calibrating the GRB data are not used to avoid any correlation between them. We find that the {Lambda}CDM model is consistent with the joint data in the 1-{sigma} confidence region, using the GRB data at high redshift calibrated with the interpolating method, the Constitution set of SNe Ia, the cosmic microwave background radiation from Wilkinson Microwave Anisotropy Probe five year observation, the baryonic acoustic oscillation from the spectroscopic Sloan Digital Sky Survey Data Release 7 galaxy sample, the x-ray baryon mass fraction in clusters of galaxies, and the observational Hubble parameter versus redshift data. Comparing to the joint constraints with GRBs and without GRBs, we find that the contribution of GRBs to the joint cosmological constraints is a slight shift in the confidence regions of cosmological parameters to better enclose the {Lambda}CDM model. Finally, we reconstruct the acceleration history of the Universe up to z>6 with the distance moduli of SNe Ia and GRBs and find some features that deviate from the {Lambda}CDM model and seem to favor oscillatory cosmology models; however, further investigations are needed to better understand the situation.« less
Shell-model predictions for Lambda Lambda hypernuclei
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gal, A.; Millener, D.
2011-06-02
It is shown how the recent shell-model determination of {Lambda}N spin-dependent interaction terms in {Lambda} hypernuclei allows for a reliable deduction of {Lambda}{Lambda} separation energies in {Lambda}{Lambda} hypernuclei across the nuclear p shell. Comparison is made with the available data, highlighting {sub {Lambda}{Lambda}}{sup 11}Be and {sub {Lambda}{Lambda}}{sup 12}Be which have been suggested as possible candidates for the KEK-E373 HIDA event.
Blind One-Bit Compressive Sampling
2013-01-17
14] Q. Li, C. A. Micchelli, L. Shen, and Y. Xu, A proximity algorithm accelerated by Gauss - Seidel iterations for L1/TV denoising models, Inverse...methods for nonconvex optimization on the unit sphere and has a provable convergence guarantees. Binary iterative hard thresholding (BIHT) algorithms were... Convergence analysis of the algorithm is presented. Our approach is to obtain a sequence of optimization problems by successively approximating the ℓ0
Yang, Yufei; Chen, Wei; Wang, Jiayu; Yang, Ziyu; Wang, Shenlin; Xiao, Xianjin; Li, Mengyuan
2018-01-01
Abstract Lambda exonuclease (λ exo) plays an important role in the resection of DNA ends for DNA repair. Currently, it is also a widely used enzymatic tool in genetic engineering, DNA-binding protein mapping, nanopore sequencing and biosensing. Herein, we disclose two noncanonical properties of this enzyme and suggest a previously undescribed hydrophobic interaction model between λ exo and DNA substrates. We demonstrate that the length of the free portion of the substrate strand in the dsDNA plays an essential role in the initiation of digestion reactions by λ exo. A dsDNA with a 5′ non-phosphorylated, two-nucleotide-protruding end can be digested by λ exo with very high efficiency. Moreover, we show that when a conjugated structure is covalently attached to an internal base of the dsDNA, the presence of a single mismatched base pair at the 5′ side of the modified base may significantly accelerate the process of digestion by λ exo. A detailed comparison study revealed additional π–π stacking interactions between the attached label and the amino acid residues of the enzyme. These new findings not only broaden our knowledge of the enzyme but will also be very useful for research on DNA repair and in vitro processing of nucleic acids. PMID:29490081
DOE Office of Scientific and Technical Information (OSTI.GOV)
Abazov, Victor Mukhamedovich
Here, we studymore » $$\\Lambda$$ and $$\\bar{\\Lambda}$$ production asymmetries in $$p \\bar{p} \\rightarrow \\Lambda (\\bar{\\Lambda}) X$$, $$p \\bar{p} \\rightarrow J/\\psi \\Lambda (\\bar{\\Lambda}) X$$, and $$p \\bar{p} \\rightarrow \\mu^\\pm \\Lambda (\\bar{\\Lambda}) X$$ events recorded by the D0 detector at the Fermilab Tevatron collider at $$\\sqrt{s} = 1.96$$ TeV. We find an excess of $$\\Lambda$$'s ($$\\bar{\\Lambda}$$'s) produced in the proton (antiproton) direction. This forward-backward asymmetry is measured as a function of rapidity. We confirm that the $$\\bar{\\Lambda}/\\Lambda$$ production ratio, measured by several experiments with various targets and a wide range of energies, is a universal function of "rapidity loss", i.e., the rapidity difference of the beam proton and the lambda.« less
Abazov, Victor Mukhamedovich
2016-02-09
Here, we studymore » $$\\Lambda$$ and $$\\bar{\\Lambda}$$ production asymmetries in $$p \\bar{p} \\rightarrow \\Lambda (\\bar{\\Lambda}) X$$, $$p \\bar{p} \\rightarrow J/\\psi \\Lambda (\\bar{\\Lambda}) X$$, and $$p \\bar{p} \\rightarrow \\mu^\\pm \\Lambda (\\bar{\\Lambda}) X$$ events recorded by the D0 detector at the Fermilab Tevatron collider at $$\\sqrt{s} = 1.96$$ TeV. We find an excess of $$\\Lambda$$'s ($$\\bar{\\Lambda}$$'s) produced in the proton (antiproton) direction. This forward-backward asymmetry is measured as a function of rapidity. We confirm that the $$\\bar{\\Lambda}/\\Lambda$$ production ratio, measured by several experiments with various targets and a wide range of energies, is a universal function of "rapidity loss", i.e., the rapidity difference of the beam proton and the lambda.« less
Diagnostics of the ITER neutral beam test facility.
Pasqualotto, R; Serianni, G; Sonato, P; Agostini, M; Brombin, M; Croci, G; Dalla Palma, M; De Muri, M; Gazza, E; Gorini, G; Pomaro, N; Rizzolo, A; Spolaore, M; Zaniol, B
2012-02-01
The ITER heating neutral beam (HNB) injector, based on negative ions accelerated at 1 MV, will be tested and optimized in the SPIDER source and MITICA full injector prototypes, using a set of diagnostics not available on the ITER HNB. The RF source, where the H(-)∕D(-) production is enhanced by cesium evaporation, will be monitored with thermocouples, electrostatic probes, optical emission spectroscopy, cavity ring down, and laser absorption spectroscopy. The beam is analyzed by cooling water calorimetry, a short pulse instrumented calorimeter, beam emission spectroscopy, visible tomography, and neutron imaging. Design of the diagnostic systems is presented.
Kihara, A; Akiyama, Y; Ito, K
1997-05-27
The cII gene product of bacteriophage lambda is unstable and required for the establishment of lysogenization. Its intracellular amount is important for the decision between lytic growth and lysogenization. Two genetic loci of Escherichia coli are crucial for these commitments of infecting lambda genome. One of them, hflA encodes the HflKC membrane protein complex, which has been believed to be a protease degrading the cII protein. However, both its absence and overproduction stabilized cII in vivo and the proposed serine protease-like sequence motif in HflC was dispensable for the lysogenization control. Moreover, the HflKC protein was found to reside on the periplasmic side of the plasma membrane. In contrast, the other host gene, ftsH (hflB) encoding an integral membrane ATPase/protease, is positively required for degradation of cII, since loss of its function stabilized cII and its overexpression accelerated the cII degradation. In vitro, purified FtsH catalyzed ATP-dependent proteolysis of cII and HflKC antagonized the FtsH action. These results, together with our previous finding that FtsH and HflKC form a complex, suggest that FtsH is the cII degrading protease and HflKC is a modulator of the FtsH function. We propose that this transmembrane modulation differentiates the FtsH actions to different substrate proteins such as the membrane-bound SecY protein and the cytosolic cII protein. This study necessitates a revision of the prevailing view about the host control over lambda lysogenic decision.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ablikim, M.; Bai, J. Z.; Cai, X.
2007-11-01
Using 58x10{sup 6} J/{psi} and 14x10{sup 6} {psi}(2S) events collected by the BESII detector at the BEPC, branching fractions or upper limits for the decays J/{psi} and {psi}(2S){yields}{lambda}{lambda}{pi}{sup 0} and {lambda}{lambda}{eta} are measured. For the isospin violating decays, the upper limits are determined to be B(J/{psi}{yields}{lambda}{lambda}{pi}{sup 0})<6.4x10{sup -5} and B[{psi}(2S){yields}{lambda}{lambda}{pi}{sup 0}]<4.9x10{sup -5} at the 90% confidence level. The isospin conserving process J/{psi}{yields}{lambda}{lambda}{eta} is observed for the first time, and its branching fraction is measured to be B(J/{psi}{yields}{lambda}{lambda}{eta})=(2.62{+-}0.60{+-}0.44)x10{sup -4}, where the first error is statistical and the second one is systematic. No {lambda}{lambda}{eta} signal is observed in {psi}(2S) decays, and B[{psi}(2S){yields}{lambda}{lambda}{eta}]<1.2x10{supmore » -4} is set at the 90% confidence level. Branching fractions of J/{psi} decays into {sigma}{sup +}{pi}{sup -}{lambda} and {sigma}{sup -}{pi}{sup +}{lambda} are also reported, and the sum of these branching fractions is determined to be B(J/{psi}{yields}{sigma}{sup +}{pi}{sup -}{lambda}+c.c.)=(1.52{+-}0.08{+-}0.16)x10{sup -3}.« less
Accelerated iterative beam angle selection in IMRT
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bangert, Mark, E-mail: m.bangert@dkfz.de; Unkelbach, Jan
2016-03-15
Purpose: Iterative methods for beam angle selection (BAS) for intensity-modulated radiation therapy (IMRT) planning sequentially construct a beneficial ensemble of beam directions. In a naïve implementation, the nth beam is selected by adding beam orientations one-by-one from a discrete set of candidates to an existing ensemble of (n − 1) beams. The best beam orientation is identified in a time consuming process by solving the fluence map optimization (FMO) problem for every candidate beam and selecting the beam that yields the largest improvement to the objective function value. This paper evaluates two alternative methods to accelerate iterative BAS based onmore » surrogates for the FMO objective function value. Methods: We suggest to select candidate beams not based on the FMO objective function value after convergence but (1) based on the objective function value after five FMO iterations of a gradient based algorithm and (2) based on a projected gradient of the FMO problem in the first iteration. The performance of the objective function surrogates is evaluated based on the resulting objective function values and dose statistics in a treatment planning study comprising three intracranial, three pancreas, and three prostate cases. Furthermore, iterative BAS is evaluated for an application in which a small number of noncoplanar beams complement a set of coplanar beam orientations. This scenario is of practical interest as noncoplanar setups may require additional attention of the treatment personnel for every couch rotation. Results: Iterative BAS relying on objective function surrogates yields similar results compared to naïve BAS with regard to the objective function values and dose statistics. At the same time, early stopping of the FMO and using the projected gradient during the first iteration enable reductions in computation time by approximately one to two orders of magnitude. With regard to the clinical delivery of noncoplanar IMRT treatments, we could show that optimized beam ensembles using only a few noncoplanar beam orientations often approach the plan quality of fully noncoplanar ensembles. Conclusions: We conclude that iterative BAS in combination with objective function surrogates can be a viable option to implement automated BAS at clinically acceptable computation times.« less
Accelerated iterative beam angle selection in IMRT.
Bangert, Mark; Unkelbach, Jan
2016-03-01
Iterative methods for beam angle selection (BAS) for intensity-modulated radiation therapy (IMRT) planning sequentially construct a beneficial ensemble of beam directions. In a naïve implementation, the nth beam is selected by adding beam orientations one-by-one from a discrete set of candidates to an existing ensemble of (n - 1) beams. The best beam orientation is identified in a time consuming process by solving the fluence map optimization (FMO) problem for every candidate beam and selecting the beam that yields the largest improvement to the objective function value. This paper evaluates two alternative methods to accelerate iterative BAS based on surrogates for the FMO objective function value. We suggest to select candidate beams not based on the FMO objective function value after convergence but (1) based on the objective function value after five FMO iterations of a gradient based algorithm and (2) based on a projected gradient of the FMO problem in the first iteration. The performance of the objective function surrogates is evaluated based on the resulting objective function values and dose statistics in a treatment planning study comprising three intracranial, three pancreas, and three prostate cases. Furthermore, iterative BAS is evaluated for an application in which a small number of noncoplanar beams complement a set of coplanar beam orientations. This scenario is of practical interest as noncoplanar setups may require additional attention of the treatment personnel for every couch rotation. Iterative BAS relying on objective function surrogates yields similar results compared to naïve BAS with regard to the objective function values and dose statistics. At the same time, early stopping of the FMO and using the projected gradient during the first iteration enable reductions in computation time by approximately one to two orders of magnitude. With regard to the clinical delivery of noncoplanar IMRT treatments, we could show that optimized beam ensembles using only a few noncoplanar beam orientations often approach the plan quality of fully noncoplanar ensembles. We conclude that iterative BAS in combination with objective function surrogates can be a viable option to implement automated BAS at clinically acceptable computation times.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Aaltonen, T.; /Helsinki Inst. of Phys.; Alvarez Gonzalez, B.
We report an analysis of the {Lambda}{sub b}{sup 0} {yields} {Lambda}{sub c}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -} decay in a data sample collected by the CDF II detector at the Fermilab Tevatron corresponding to 2.4 fb{sup -1} of integrated luminosity. We reconstruct the currently largest samples of the decay modes {Lambda}{sub b}{sup 0} {yields} {Lambda}{sub c}(2595){sup +}{pi}{sup -} (with {Lambda}{sub c}(2595){sup +} {yields} {Lambda}{sub c}{sup +}{pi}{sup +}{pi}{sup -}), {Lambda}{sub b}{sup 0} {yields} {Lambda}{sub c}(2625){sup +}{pi}{sup -} (with {Lambda}{sub c}(2625){sup +} {yields} {Lambda}{sub c}{sup +}{pi}{sup +}{pi}{sup -}), {Lambda}{sub b}{sup 0} {yields} {Sigma}{sub c}(2455){sup ++}{pi}{sup -}{pi}{sup -} (with {Sigma}{sub c}(2455){sup ++} {yields} {Lambda}{submore » c}{sup +}{pi}{sup +}), and {Lambda}{sub b}{sup 0} {yields} {Sigma}{sub c}(2455)0{pi}{sup +}{pi}{sup -} (with {Sigma}{sub c}(2455)0 {yields} {Lambda}{sub c}{sup +}{pi}{sup -}) and measure the branching fractions relative to the {Lambda}{sub b}{sup 0} {yields} {Lambda}{sub c}{sup +}{pi}{sup -} branching fraction. We measure the ratio {Beta}({Lambda}{sub b}{sup 0} {yields} {Lambda}{sub c}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -})/ {Beta}({Lambda}{sub b}{sup 0} {yields} {Lambda}{sub c}{sup +}{pi}{sup -})=3.04 {+-} 0.33(stat){sub -0.55}{sup +0.70}(syst) which is used to derive {Beta}({Lambda}{sub b}{sup 0} {yields} {Lambda}{sub c}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -})=(26.8{sub -11.2}{sup +11.9}) x 10{sup -3}.« less
Study of B{yields}{lambda}{sub c}{lambda}{sub c} and B{yields}{lambda}{sub c}{lambda}{sub c}K
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cheng, H.-Y.; Hsiao, Y.-K.; Chua, C.-K.
2009-06-01
We study the doubly charmful two-body and three-body baryonic B decays B{yields}{lambda}{sub c}{sup +}{lambda}{sub c}{sup -} and B{yields}{lambda}{sub c}{sup +}{lambda}{sub c}{sup -}K. As pointed out before, a naive estimate of the branching ratio O(10{sup -8}) for the latter decay is too small by 3 to 4 orders of magnitude compared to experiment. Previously, it has been shown that a large enhancement for the {lambda}{sub c}{sup +}{lambda}{sub c}{sup -}K production can occur due to a charmoniumlike resonance (e.g. X(4630) discovered by Belle) with a mass near the {lambda}{sub c}{lambda}{sub c} threshold. Motivated by the BABAR's observation of a resonance in themore » {lambda}{sub c}K system with a mass of order 2930 MeV, we study in this work the contribution to B{yields}{lambda}{sub c}{sup +}{lambda}{sub c}{sup -}K from the intermediate state {xi}{sub c}(2980) which is postulated to be a first positive-parity excited D-wave charmed baryon state. Assuming that a soft qq quark pair is produced through the {sigma} and {pi} meson exchanges in the configuration for B{yields}{xi}{sub c}(2980){lambda}{sub c} and {lambda}{sub c}{lambda}{sub c}, it is found that branching ratios of B{yields}{lambda}{sub c}{sup +}{lambda}{sub c}{sup -}K and B{yields}{lambda}{sub c}{sup +}{lambda}{sub c}{sup -} are of order 3.5x10{sup -4} and 5x10{sup -5}, respectively, in agreement with experiment except that the prediction for the {lambda}{sub c}{lambda}{sub c}K{sup -} is slightly smaller. In conjunction with our previous analysis, we conclude that the enormously large rate of B{yields}{lambda}{sub c}{sup +}{lambda}{sub c}{sup -}K arises from the resonances {xi}{sub c}(2980) and X(4630)« less
Chatrchyan, Serguei; et al.
2013-07-16
The Lambda(b) differential production cross section and the cross section ratio anti-Lambda(b)/Lambda(b) are measured as functions of transverse momentum pt(Lambda(b)) and rapidity abs(y(Lambda(b))) in pp collisions at sqrt(s) = 7 TeV using data collected by the CMS experiment at the LHC. The measurements are based on Lambda(b) decays reconstructed in the exclusive final state J/Psi Lambda, with the subsequent decays J/Psi to an opposite-sign muon pair and Lambda to proton pion, using a data sample corresponding to an integrated luminosity of 1.9 inverse femtobarns. The product of the cross section times the branching ratio for Lambda(b) to J/Psi Lambda versusmore » pt(Lambda(b)) falls faster than that of b mesons. The measured value of the cross section times the branching ratio for pt(Lambda(b)) > 10 GeV and abs(y(Lambda(b))) < 2.0 is 1.06 +/- 0.06 +/- 0.12 nb, and the integrated cross section ratio for anti-Lambda(b)/Lambda(b) is 1.02 +/- 0.07 +/- 0.09, where the uncertainties are statistical and systematic, respectively.« less
The PRIMA Test Facility: SPIDER and MITICA test-beds for ITER neutral beam injectors
NASA Astrophysics Data System (ADS)
Toigo, V.; Piovan, R.; Dal Bello, S.; Gaio, E.; Luchetta, A.; Pasqualotto, R.; Zaccaria, P.; Bigi, M.; Chitarin, G.; Marcuzzi, D.; Pomaro, N.; Serianni, G.; Agostinetti, P.; Agostini, M.; Antoni, V.; Aprile, D.; Baltador, C.; Barbisan, M.; Battistella, M.; Boldrin, M.; Brombin, M.; Dalla Palma, M.; De Lorenzi, A.; Delogu, R.; De Muri, M.; Fellin, F.; Ferro, A.; Fiorentin, A.; Gambetta, G.; Gnesotto, F.; Grando, L.; Jain, P.; Maistrello, A.; Manduchi, G.; Marconato, N.; Moresco, M.; Ocello, E.; Pavei, M.; Peruzzo, S.; Pilan, N.; Pimazzoni, A.; Recchia, M.; Rizzolo, A.; Rostagni, G.; Sartori, E.; Siragusa, M.; Sonato, P.; Sottocornola, A.; Spada, E.; Spagnolo, S.; Spolaore, M.; Taliercio, C.; Valente, M.; Veltri, P.; Zamengo, A.; Zaniol, B.; Zanotto, L.; Zaupa, M.; Boilson, D.; Graceffa, J.; Svensson, L.; Schunke, B.; Decamps, H.; Urbani, M.; Kushwah, M.; Chareyre, J.; Singh, M.; Bonicelli, T.; Agarici, G.; Garbuglia, A.; Masiello, A.; Paolucci, F.; Simon, M.; Bailly-Maitre, L.; Bragulat, E.; Gomez, G.; Gutierrez, D.; Mico, G.; Moreno, J.-F.; Pilard, V.; Kashiwagi, M.; Hanada, M.; Tobari, H.; Watanabe, K.; Maejima, T.; Kojima, A.; Umeda, N.; Yamanaka, H.; Chakraborty, A.; Baruah, U.; Rotti, C.; Patel, H.; Nagaraju, M. V.; Singh, N. P.; Patel, A.; Dhola, H.; Raval, B.; Fantz, U.; Heinemann, B.; Kraus, W.; Hanke, S.; Hauer, V.; Ochoa, S.; Blatchford, P.; Chuilon, B.; Xue, Y.; De Esch, H. P. L.; Hemsworth, R.; Croci, G.; Gorini, G.; Rebai, M.; Muraro, A.; Tardocchi, M.; Cavenago, M.; D'Arienzo, M.; Sandri, S.; Tonti, A.
2017-08-01
The ITER Neutral Beam Test Facility (NBTF), called PRIMA (Padova Research on ITER Megavolt Accelerator), is hosted in Padova, Italy and includes two experiments: MITICA, the full-scale prototype of the ITER heating neutral beam injector, and SPIDER, the full-size radio frequency negative-ions source. The NBTF realization and the exploitation of SPIDER and MITICA have been recognized as necessary to make the future operation of the ITER heating neutral beam injectors efficient and reliable, fundamental to the achievement of thermonuclear-relevant plasma parameters in ITER. This paper reports on design and R&D carried out to construct PRIMA, SPIDER and MITICA, and highlights the huge progress made in just a few years, from the signature of the agreement for the NBTF realization in 2011, up to now—when the buildings and relevant infrastructures have been completed, SPIDER is entering the integrated commissioning phase and the procurements of several MITICA components are at a well advanced stage.
Physics design of the injector source for ITER neutral beam injector (invited).
Antoni, V; Agostinetti, P; Aprile, D; Cavenago, M; Chitarin, G; Fonnesu, N; Marconato, N; Pilan, N; Sartori, E; Serianni, G; Veltri, P
2014-02-01
Two Neutral Beam Injectors (NBI) are foreseen to provide a substantial fraction of the heating power necessary to ignite thermonuclear fusion reactions in ITER. The development of the NBI system at unprecedented parameters (40 A of negative ion current accelerated up to 1 MV) requires the realization of a full scale prototype, to be tested and optimized at the Test Facility under construction in Padova (Italy). The beam source is the key component of the system and the design of the multi-grid accelerator is the goal of a multi-national collaborative effort. In particular, beam steering is a challenging aspect, being a tradeoff between requirements of the optics and real grids with finite thickness and thermo-mechanical constraints due to the cooling needs and the presence of permanent magnets. In the paper, a review of the accelerator physics and an overview of the whole R&D physics program aimed to the development of the injector source are presented.
Benkert, Thomas; Tian, Ye; Huang, Chenchan; DiBella, Edward V R; Chandarana, Hersh; Feng, Li
2018-07-01
Golden-angle radial sparse parallel (GRASP) MRI reconstruction requires gridding and regridding to transform data between radial and Cartesian k-space. These operations are repeatedly performed in each iteration, which makes the reconstruction computationally demanding. This work aimed to accelerate GRASP reconstruction using self-calibrating GRAPPA operator gridding (GROG) and to validate its performance in clinical imaging. GROG is an alternative gridding approach based on parallel imaging, in which k-space data acquired on a non-Cartesian grid are shifted onto a Cartesian k-space grid using information from multicoil arrays. For iterative non-Cartesian image reconstruction, GROG is performed only once as a preprocessing step. Therefore, the subsequent iterative reconstruction can be performed directly in Cartesian space, which significantly reduces computational burden. Here, a framework combining GROG with GRASP (GROG-GRASP) is first optimized and then compared with standard GRASP reconstruction in 22 prostate patients. GROG-GRASP achieved approximately 4.2-fold reduction in reconstruction time compared with GRASP (∼333 min versus ∼78 min) while maintaining image quality (structural similarity index ≈ 0.97 and root mean square error ≈ 0.007). Visual image quality assessment by two experienced radiologists did not show significant differences between the two reconstruction schemes. With a graphics processing unit implementation, image reconstruction time can be further reduced to approximately 14 min. The GRASP reconstruction can be substantially accelerated using GROG. This framework is promising toward broader clinical application of GRASP and other iterative non-Cartesian reconstruction methods. Magn Reson Med 80:286-293, 2018. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.
Simulated O VI Doppler dimming measurements of coronal outflow velocities
NASA Technical Reports Server (NTRS)
Strachan, Leonard; Gardner, L. D.; Kohl, John L.
1992-01-01
The possibility of determining O(5+) outflow velocities by using a Doppler dimming analysis of the resonantly scattered intensities of O VI lambda 1031.9 and lambda 1037.6 is addressed. The technique is sensitive to outflow velocities, W, in the range W greater than 30 and less than 250 km/s and can be used for probing regions of the inner solar corona, where significant coronal heating and solar wind acceleration may be occurring. These velocity measurements, when combined with measurements of other plasma parameters (temperatures and densities of ions and electrons) can be used to estimate the energy and mass flux of O(5+). In particular, it may be possible to locate where the flow changes from subsonic to supersonic and to identify source regions for the high and low speed solar wind. The velocity diagnostic technique is discussed with emphasis placed on the requirements needed for accurate outflow velocity determinations. Model determinations of outflow velocities based on simulated Doppler observations are presented.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Compton, N.; Taylor, C. E.; Hicks, K.
Here, we report the first measurement of differential and total cross sections for themore » $${\\gamma}d \\to K^0{\\Lambda}(p)$$ reaction, using data from the CLAS detector at the Thomas Jefferson National Accelerator Facility. Data collected during two separate experimental runs were studied with photon-energy coverage 0.8 - 3.6 GeV and 0.5 - 2.6 GeV, respectively. The two measurements are consistent giving confidence in the method and determination of systematic uncertainties. The cross sections are compared with predictions from the KAON-MAID theoretical model (without kaon exchange), which deviate from the data at higher W and at forward kaon angles. These data, along with previously published cross sections for $$K^+ {\\Lambda}$$ photoproduction, provide essential constraints on the nucleon resonance spectrum. A first partial wave analysis has been performed that describes the data without the introduction of new resonances.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Compton, N.; Taylor, C. E.; Hicks, K.
We report the first measurement of differential and total cross sections for the gamma d -> K-0 Lambda(p) reaction, using data from the CLAS detector at the Thomas Jefferson National Accelerator Facility. Data collected during two separate experimental runs were studied with photon-energy coverage 0.8-3.6 GeV and 0.5-2.6 GeV, respectively. The two measurements are consistent giving confidence in the method and determination of systematic uncertainties. The cross sections are compared with predictions from the KAON-MAID theoretical model (without kaon exchange), which deviate from the data at higher W and at forward kaon angles. These data, along with previously published crossmore » sections for K+Lambda photoproduction, provide essential constraints on the nucleon resonance spectrum. A first partial wave analysis was performed that describes the data without the introduction of new resonances.« less
Full-color laser cathode ray tube (L-CRT) projector
NASA Astrophysics Data System (ADS)
Kozlovskiy, Vladimir; Nasibov, Alexander S.; Popov, Yuri M.; Reznikov, Parvel V.; Skasyrsky, Yan K.
1995-04-01
A full color TV projector based on three laser cathode-ray tubes (L-CRT) is described. A water-cooled laser screen (LS) is the radiation element of the L-CRT. We have produced three main colors (blue, green and red) by using the LS made of three II-VI compounds: ZnSe ((lambda) equals 475 nm), CdS ((lambda) equals 530 nm) and ZnCdSe (630 nm). The total light flow reaches 1500 Lm, and the number of elements per line is not less than 1000. The LS efficiency may be about 10 Lm/W. In our experiments we have tested new electron optics: - (30 - 37) kV are applied to the cathode unit of the electron gun; the anode of the e-gun and the e-beam intensity modulator are under low potential; the LS has a potential + (30 - 37) kV. The accelerating voltage is divided into two parts, and this enables us to diminish the size and weight of the projector.
Compton, N.; Taylor, C. E.; Hicks, K.; ...
2017-12-04
Here, we report the first measurement of differential and total cross sections for themore » $${\\gamma}d \\to K^0{\\Lambda}(p)$$ reaction, using data from the CLAS detector at the Thomas Jefferson National Accelerator Facility. Data collected during two separate experimental runs were studied with photon-energy coverage 0.8 - 3.6 GeV and 0.5 - 2.6 GeV, respectively. The two measurements are consistent giving confidence in the method and determination of systematic uncertainties. The cross sections are compared with predictions from the KAON-MAID theoretical model (without kaon exchange), which deviate from the data at higher W and at forward kaon angles. These data, along with previously published cross sections for $$K^+ {\\Lambda}$$ photoproduction, provide essential constraints on the nucleon resonance spectrum. A first partial wave analysis has been performed that describes the data without the introduction of new resonances.« less
[The expression of interferon-lambda1 in CHO cell].
Yuan, Wu-Mei; Ma, Fen-Lian; Zhang, Qian; Zheng, Wen-Zhi; Zheng, Li-Shu
2013-06-01
To construct the eukaryotic expression vector PCI-dhfr-lambda1 and PCI-dhfr-SP163-lambda1 which linked the enhancer SP163 with interferon lambda1. Then express the interferon lambda1 in CHO (dhfr-) cells. Using PCR method to introduce the restriction enzyme sites and through the fusion PCR binding the enhancer with the interferon Lambda1. After sequenced, lambda1 and SP163-lambda1 was inserted into PCI-dhfr forming the expression vector PCI-dhfr-lambda1 and PCI-dhfr-SP163-lambda1 which was constructed successfully confirming by sequencing. Then the expressing vectors were transfected into CHO (dhfr-) cells using liposome transfection method and interferon lambda1 protein was assayed with indirect immunofluorescence and Western Blot. Using cytopathic effect inhibition evaluated the antiviral activity of interferon lambda1. Successfully constructing the eukaryotic expression vectors of interferon lambda and the vectors could express interferon lambda1. The result of immunofluorescence showed the enhancer developed the expression of interferon lambda1. Detecting the interferon lambda1 in CHO (dhfr-) cells after transfecting 48 hour using Western Blot. The cytopathic effect inhibition showed the expressed interferon lambda1 has the antiviral activity. Successfully expressed the interferon lambda1 in CHO (dhfr-) cells and the protein possesses antiviral activity, which may supply a valuable basis for building the stable cell line of interferon lambda1.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Shoeb, Mohammad; Sonika
2009-08-15
The energies of the ground and excited 2{sup +} states of {sub {lambda}}{sub {lambda}}{sup 10}Be have been calculated variationally in the Monte Carlo framework. The hypernucleus is treated as a partial ten-body problem in the {lambda}{lambda}+{alpha}{alpha} model where nucleonic degrees of freedom of {alpha}'s are taken into consideration ignoring the antisymmetrization between two {alpha}'s. The central two-body {lambda}N and {lambda}{lambda} and the three-body dispersive and two-pion exchange {lambda}NN forces, constrained by the {lambda}p scattering data and the observed ground state energies of {sub {lambda}}{sup 5}He and {sub {lambda}}{sub {lambda}}{sup 6}He, are employed. The product-type trial wave function predicts binding energymore » for the ground state considerably less than for the event reported by Danysz et al.; however, it is consistent with the value deduced assuming a {gamma} ray of 3.04 MeV must have escaped undetected in the decay of the product {sub {lambda}}{sup 9}Be* {yields} {sub {lambda}}{sup 9}Be+{gamma} of the emulsion event {sub {lambda}}{sub {lambda}}{sup 10}Be{yields} {pi}{sup -}+p+{sub {lambda}}{sup 9}Be* and for the excited 2{sup +} state closer to the value measured in the Demachi-Yanagi event. The hypernucleus {sub {lambda}}{sub {lambda}}{sup 10}Be has an oblate shape in the excited state. These results are consistent with the earlier four-body {alpha} cluster model approach where {alpha}'s are assumed to be structureless entities.« less
NASA Astrophysics Data System (ADS)
Narayan, Ramesh; Zhu, Yucong; Psaltis, Dimitrios; Saḑowski, Aleksander
2016-03-01
We describe Hybrid Evaluator for Radiative Objects Including Comptonization (HEROIC), an upgraded version of the relativistic radiative post-processor code HERO described in a previous paper, but which now Includes Comptonization. HEROIC models Comptonization via the Kompaneets equation, using a quadratic approximation for the source function in a short characteristics radiation solver. It employs a simple form of accelerated lambda iteration to handle regions of high scattering opacity. In addition to solving for the radiation field, HEROIC also solves for the gas temperature by applying the condition of radiative equilibrium. We present benchmarks and tests of the Comptonization module in HEROIC with simple 1D and 3D scattering problems. We also test the ability of the code to handle various relativistic effects using model atmospheres and accretion flows in a black hole space-time. We present two applications of HEROIC to general relativistic magnetohydrodynamics simulations of accretion discs. One application is to a thin accretion disc around a black hole. We find that the gas below the photosphere in the multidimensional HEROIC solution is nearly isothermal, quite different from previous solutions based on 1D plane parallel atmospheres. The second application is to a geometrically thick radiation-dominated accretion disc accreting at 11 times the Eddington rate. Here, the multidimensional HEROIC solution shows that, for observers who are on axis and look down the polar funnel, the isotropic equivalent luminosity could be more than 10 times the Eddington limit, even though the spectrum might still look thermal and show no signs of relativistic beaming.
Water isotopologues in the circumstellar envelopes of M-type AGB stars
NASA Astrophysics Data System (ADS)
Danilovich, T.; Lombaert, R.; Decin, L.; Karakas, A.; Maercker, M.; Olofsson, H.
2017-06-01
Aims: In this study we intend to examine rotational emission lines of two isotopologues of water: H217O and H218O. By determining the abundances of these molecules, we aim to use the derived isotopologue - and hence oxygen isotope - ratios to put constraints on the masses of a sample of M-type AGB stars that have not been classified as OH/IR stars. Methods: We have used detailed radiative transfer analysis based on the accelerated lambda iteration method to model the circumstellar molecular line emission of H217O and H218O for IK Tau, R Dor, W Hya, and R Cas. The emission lines used to constrain our models came from Herschel/HIFI and Herschel/PACS observations and are all optically thick, meaning that full radiative transfer analysis is the only viable method of estimating molecular abundance ratios. Results: We find generally low values of the 17O/18O ratio for our sample, ranging from 0.15 to 0.69. This correlates with relatively low initial masses, in the range 1.0 to 1.5 M⊙ for each source, based on stellar evolutionary models. We also find ortho-to-para ratios close to 3, which are expected from warm formation predictions. Conclusions: The 17O/18O ratios found for this sample are at the lower end of the range predicted by stellar evolutionary models, indicating that the sample chosen had relatively low initial masses. Herschel is an ESA space observatory with science instruments provided by European-led Principal Investigator consortia and with important participation from NASA.
Evidence of a significant rotational non-LTE effect in the CO2 4.3 µm PFS-MEX limb spectra
NASA Astrophysics Data System (ADS)
Kutepov, Alexander A.; Rezac, Ladislav; Feofilov, Artem G.
2017-01-01
Since January 2004, the planetary Fourier spectrometer (PFS) on board the Mars Express satellite has been recording near-infrared limb spectra of high quality up to the tangent altitudes ≈ 150 km, with potential information on density and thermal structure of the upper Martian atmosphere. We present first results of our modeling of the PFS short wavelength channel (SWC) daytime limb spectra for the altitude region above 90 km. We applied a ro-vibrational non-LTE model based on the stellar astrophysics technique of accelerated lambda iteration (ALI) to solve the multi-species and multi-level CO2 problem in the Martian atmosphere. We show that the long-standing discrepancy between observed and calculated spectra in the cores and wings of 4.3 µm region is explained by the non-thermal rotational distribution of molecules in the upper vibrational states 10011 and 10012 of the CO2 main isotope second hot (SH) bands above 90 km altitude. The redistribution of SH band intensities from band branch cores into their wings is caused (a) by intensive production of the CO2 molecules in rotational states with j > 30 due to the absorption of solar radiation in optically thin wings of 2.7 µm bands and (b) by a short radiative lifetime of excited molecules, which is insufficient at altitudes above 90 km for collisions to maintain rotation of excited molecules thermalized. Implications for developing operational algorithms for massive processing of PFS and other instrument limb observations are discussed.
Code Samples Used for Complexity and Control
NASA Astrophysics Data System (ADS)
Ivancevic, Vladimir G.; Reid, Darryn J.
2015-11-01
The following sections are included: * MathematicaⓇ Code * Generic Chaotic Simulator * Vector Differential Operators * NLS Explorer * 2C++ Code * C++ Lambda Functions for Real Calculus * Accelerometer Data Processor * Simple Predictor-Corrector Integrator * Solving the BVP with the Shooting Method * Linear Hyperbolic PDE Solver * Linear Elliptic PDE Solver * Method of Lines for a Set of the NLS Equations * C# Code * Iterative Equation Solver * Simulated Annealing: A Function Minimum * Simple Nonlinear Dynamics * Nonlinear Pendulum Simulator * Lagrangian Dynamics Simulator * Complex-Valued Crowd Attractor Dynamics * Freeform Fortran Code * Lorenz Attractor Simulator * Complex Lorenz Attractor * Simple SGE Soliton * Complex Signal Presentation * Gaussian Wave Packet * Hermitian Matrices * Euclidean L2-Norm * Vector/Matrix Operations * Plain C-Code: Levenberg-Marquardt Optimizer * Free Basic Code: 2D Crowd Dynamics with 3000 Agents
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kryemadhi, Abaz
The results from Tevatron in the baryonic sector are presented. The lifetime of {lambda}b {yields} J/{psi}{lambda}, the observation of hadronic decay of {lambda}b {yields} {lambda}c{pi}, the semileptonic decays of {lambda}b {yields} {lambda}c{mu}{nu}, the hadronization of the b-baryons, and the {lambda}b decays to {lambda}b {yields} p{pi} and {lambda}b {yields} pK are discussed. These measurements paint a nice picture of our understanding of the beauty baryons.
On the Global and Linear Convergence of the Generalized Alternating Direction Method of Multipliers
2012-08-01
the less exact one is solved later — assigned as step 4 of Algorithm 2 — because at each iteration , the ADM updates the variables in the Gauss - Seidel ...k) and that of an accelerated version descends at O(1/k2). Then, work [14] establishes the same rates on a Gauss - Seidel version and requires only one... iteration Fig. 5.1. Convergence curves of ADM for the elastic net problem. 17 0 50 100 150 200 0.75 0.8 0.85 0.9 0.95 1 Iteration ‖u k + 1 − u ∗ ‖ 2 G / ‖u k
Improved measurement of the form factors in the decay lambda+c-->lambda + nue.
Hinson, J W; Huang, G S; Lee, J; Miller, D H; Pavlunin, V; Rangarajan, R; Sanghi, B; Shibata, E I; Shipsey, I P J; Cronin-Hennessy, D; Park, C S; Park, W; Thayer, J B; Thorndike, E H; Coan, T E; Gao, Y S; Liu, F; Stroynowski, R; Artuso, M; Boulahouache, C; Blusk, S; Dambasuren, E; Dorjkhaidav, O; Mountain, R; Muramatsu, H; Nandakumar, R; Skwarnicki, T; Stone, S; Wang, J C; Csorna, S E; Danko, I; Bonvicini, G; Cinabro, D; Dubrovin, M; McGee, S; Bornheim, A; Lipeles, E; Pappas, S P; Shapiro, A; Sun, W M; Weinstein, A J; Briere, R A; Chen, G P; Ferguson, T; Tatishvili, G; Vogel, H; Watkins, M E; Adam, N E; Alexander, J P; Berkelman, K; Boisvert, V; Cassel, D G; Duboscq, J E; Ecklund, K M; Ehrlich, R; Galik, R S; Gibbons, L; Gittelman, B; Gray, S W; Hartill, D L; Heltsley, B K; Hsu, L; Jones, C D; Kandaswamy, J; Kreinick, D L; Magerkurth, A; Mahlke-Krüger, H; Meyer, T O; Mistry, N B; Patterson, J R; Peterson, D; Pivarski, J; Richichi, S J; Riley, D; Sadoff, A J; Schwarthoff, H; Shepherd, M R; Thayer, J G; Urner, D; Wilksen, T; Warburton, A; Weinberger, M; Athar, S B; Avery, P; Breva-Newell, L; Potlia, V; Stoeck, H; Yelton, J; Benslama, K; Cawlfield, C; Eisenstein, B I; Gollin, G D; Karliner, I; Lowrey, N; Plager, C; Sedlack, C; Selen, M; Thaler, J J; Williams, J; Edwards, K W; Besson, D; Anderson, S; Frolov, V V; Gong, D T; Kubota, Y; Li, S Z; Poling, R; Smith, A; Stepaniak, C J; Urheim, J; Metreveli, Z; Seth, K K; Tomaradze, A; Zweber, P; Ahmed, S; Alam, M S; Ernst, J; Jian, L; Saleem, M; Wappler, F; Arms, K; Eckhart, E; Gan, K K; Gwon, C; Honscheid, K; Kagan, H; Kass, R; Pedlar, T K; von Toerne, E; Severini, H; Skubic, P; Dytman, S A; Mueller, J A; Nam, S; Savinov, V
2005-05-20
Using the CLEO detector at the Cornell Electron Storage Ring, we have studied the distribution of kinematic variables in the decay lambda(+)(c)lambda--> e(+)nu(e). By performing a four-dimensional maximum likelihood fit, we determine the form factor ratio, R= f(2)/f(1) = -0.31 +/- 0.05(stat) +/- 0.04(syst), the pole mass, M(pole) = [2.21 +/- 0.08(stat) +/- 0.14(syst)] GeV/c(2), and the decay asymmetry parameter of the lambda(+)(c), alpha (lambda(c)) = -0.86 +/-0.03(stat) +/- 0.02(syst), for q(2) = 0.67 (GeV/c(2))(2). We compare the angular distributions of the lambda(+)(c) and lambda(-)(c) and find no evidence for CP violation: A(lambda(c)) = (alpha(lambda(c)) + alpha (lambda(c)))/(alpha(lambda(c))-alpha(lambda(c))) = 0.00 +/- 0.03(stat) +/- 0.01(syst) +/- 0.02, where the third error is from the uncertainty in the world average of the CP-violating parameter, A(lambda), for ppi(-).
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chang, Y.-W.; Wang, M.-Z.; Chao, Y.
2009-03-01
We study the charmless decays B{yields}{lambda}{lambda}h, where h stands for {pi}{sup +}, K{sup +}, K{sup 0},K*{sup +}, or K*{sup 0}, using a 605 fb{sup -1} data sample collected at the {upsilon}(4S) resonance with the Belle detector at the KEKB asymmetric energy e{sup +}e{sup -} collider. We observe B{sup 0}{yields}{lambda}{lambda}K{sup 0} and B{sup 0}{yields}{lambda}{lambda}K*{sup 0} with branching fractions of (4.76{sub -0.68}{sup +0.84}(stat){+-}0.61(syst))x10{sup -6} and (2.46{sub -0.72}{sup +0.87}{+-}0.34)x10{sup -6}, respectively. The significances of these signals in the threshold-mass enhanced mass region, M{sub {lambda}}{sub {lambda}}<2.85 GeV/c{sup 2}, are 12.4{sigma} and 9.3{sigma}, respectively. We also update the branching fraction B(B{sup +}{yields}{lambda}{lambda}K{sup +})=(3.38{sub -0.36}{sup +0.41}{+-}0.41)x10{supmore » -6} with better accuracy, and report the following measurement or 90% confidence level upper limit in the threshold-mass-enhanced region: B(B{sup +}{yields}{lambda}{lambda}K*{sup +})=(2.19{sub -0.88}{sup +1.13}{+-}0.33)x10{sup -6} with 3.7{sigma} significance; B(B{sup +}{yields}{lambda}{lambda}{pi}{sup +})<0.94x10{sup -6}. A related search for B{sup 0}{yields}{lambda}{lambda}D{sup 0} yields a branching fraction B(B{sup 0}{yields}{lambda}{lambda}D{sup 0})=(1.05{sub -0.44}{sup +0.57}{+-}0.14)x10{sup -5}. This may be compared with the large, {approx}10{sup -4}, branching fraction observed for B{sup 0}{yields}ppD{sup 0}. The M{sub {lambda}}{sub {lambda}} enhancements near threshold and related angular distributions for the observed modes are also reported.« less
Osipiuk, J; Georgopoulos, C; Zylicz, M
1993-03-05
It is known that the initiation of bacteriophage lambda replication requires the orderly assembly of the lambda O.lambda P.DnaB helicase protein preprimosomal complex at the ori lambda DNA site. The DnaK, DnaJ, and GrpE heat shock proteins act together to destabilize the lambda P.DnaB complex, thus freeing DnaB and allowing it to unwind lambda DNA near the ori lambda site. The first step of this disassembly reaction is the binding of DnaK to the lambda P protein. In this report, we examined the influence of the DnaJ and GrpE proteins on the stability of the lambda P.DnaK complex. We present evidence for the existence of the following protein-protein complexes: lambda P.DnaK, lambda P.DnaJ, DnaJ.DnaK, DnaK.GrpE, and lambda P.DnaK.GrpE. Our results suggest that the presence of GrpE alone destabilizes the lambda P.DnaK complex, whereas the presence of DnaJ alone stabilizes the lambda P.DnaK complex. Using immunoprecipitation, we show that in the presence of GrpE, DnaK exhibits a higher affinity for the lambda P.DnaJ complex than it does alone. Using cross-linking with glutaraldehyde, we show that oligomeric forms of DnaK exhibit a higher affinity for lambda P than monomeric DnaK. However, in the presence of GrpE, monomeric DnaK can efficiently bind lambda P protein. These findings help explain our previous results, namely that in the GrpE-dependent lambda DNA replication system, the DnaK protein requirement can be reduced up to 10-fold.
Nonnegative least-squares image deblurring: improved gradient projection approaches
NASA Astrophysics Data System (ADS)
Benvenuto, F.; Zanella, R.; Zanni, L.; Bertero, M.
2010-02-01
The least-squares approach to image deblurring leads to an ill-posed problem. The addition of the nonnegativity constraint, when appropriate, does not provide regularization, even if, as far as we know, a thorough investigation of the ill-posedness of the resulting constrained least-squares problem has still to be done. Iterative methods, converging to nonnegative least-squares solutions, have been proposed. Some of them have the 'semi-convergence' property, i.e. early stopping of the iteration provides 'regularized' solutions. In this paper we consider two of these methods: the projected Landweber (PL) method and the iterative image space reconstruction algorithm (ISRA). Even if they work well in many instances, they are not frequently used in practice because, in general, they require a large number of iterations before providing a sensible solution. Therefore, the main purpose of this paper is to refresh these methods by increasing their efficiency. Starting from the remark that PL and ISRA require only the computation of the gradient of the functional, we propose the application to these algorithms of special acceleration techniques that have been recently developed in the area of the gradient methods. In particular, we propose the application of efficient step-length selection rules and line-search strategies. Moreover, remarking that ISRA is a scaled gradient algorithm, we evaluate its behaviour in comparison with a recent scaled gradient projection (SGP) method for image deblurring. Numerical experiments demonstrate that the accelerated methods still exhibit the semi-convergence property, with a considerable gain both in the number of iterations and in the computational time; in particular, SGP appears definitely the most efficient one.
Liberek, K; Osipiuk, J; Zylicz, M; Ang, D; Skorko, J; Georgopoulos, C
1990-02-25
The process of initiation of lambda DNA replication requires the assembly of the proper nucleoprotein complex at the origin of replication, ori lambda. The complex is composed of both phage and host-coded proteins. The lambda O initiator protein binds specifically to ori lambda. The lambda P initiator protein binds to both lambda O and the host-coded dnaB helicase, giving rise to an ori lambda DNA.lambda O.lambda P.dnaB structure. The dnaK and dnaJ heat shock proteins have been shown capable of dissociating this complex. The thus freed dnaB helicase unwinds the duplex DNA template at the replication fork. In this report, through cross-linking, size chromatography, and protein affinity chromatography, we document some of the protein-protein interactions occurring at ori lambda. Our results show that the dnaK protein specifically interacts with both lambda O and lambda P, and that the dnaJ protein specifically interacts with the dnaB helicase.
A new least-squares transport equation compatible with voids
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hansen, J. B.; Morel, J. E.
2013-07-01
We define a new least-squares transport equation that is applicable in voids, can be solved using source iteration with diffusion-synthetic acceleration, and requires only the solution of an independent set of second-order self-adjoint equations for each direction during each source iteration. We derive the equation, discretize it using the S{sub n} method in conjunction with a linear-continuous finite-element method in space, and computationally demonstrate various of its properties. (authors)
Accelerating Families of Fuzzy K-Means Algorithms for Vector Quantization Codebook Design
Mata, Edson; Bandeira, Silvio; de Mattos Neto, Paulo; Lopes, Waslon; Madeiro, Francisco
2016-01-01
The performance of signal processing systems based on vector quantization depends on codebook design. In the image compression scenario, the quality of the reconstructed images depends on the codebooks used. In this paper, alternatives are proposed for accelerating families of fuzzy K-means algorithms for codebook design. The acceleration is obtained by reducing the number of iterations of the algorithms and applying efficient nearest neighbor search techniques. Simulation results concerning image vector quantization have shown that the acceleration obtained so far does not decrease the quality of the reconstructed images. Codebook design time savings up to about 40% are obtained by the accelerated versions with respect to the original versions of the algorithms. PMID:27886061
Accelerating Families of Fuzzy K-Means Algorithms for Vector Quantization Codebook Design.
Mata, Edson; Bandeira, Silvio; de Mattos Neto, Paulo; Lopes, Waslon; Madeiro, Francisco
2016-11-23
The performance of signal processing systems based on vector quantization depends on codebook design. In the image compression scenario, the quality of the reconstructed images depends on the codebooks used. In this paper, alternatives are proposed for accelerating families of fuzzy K-means algorithms for codebook design. The acceleration is obtained by reducing the number of iterations of the algorithms and applying efficient nearest neighbor search techniques. Simulation results concerning image vector quantization have shown that the acceleration obtained so far does not decrease the quality of the reconstructed images. Codebook design time savings up to about 40% are obtained by the accelerated versions with respect to the original versions of the algorithms.
NASA Astrophysics Data System (ADS)
Zerr, Robert Joseph
2011-12-01
The integral transport matrix method (ITMM) has been used as the kernel of new parallel solution methods for the discrete ordinates approximation of the within-group neutron transport equation. The ITMM abandons the repetitive mesh sweeps of the traditional source iterations (SI) scheme in favor of constructing stored operators that account for the direct coupling factors among all the cells and between the cells and boundary surfaces. The main goals of this work were to develop the algorithms that construct these operators and employ them in the solution process, determine the most suitable way to parallelize the entire procedure, and evaluate the behavior and performance of the developed methods for increasing number of processes. This project compares the effectiveness of the ITMM with the SI scheme parallelized with the Koch-Baker-Alcouffe (KBA) method. The primary parallel solution method involves a decomposition of the domain into smaller spatial sub-domains, each with their own transport matrices, and coupled together via interface boundary angular fluxes. Each sub-domain has its own set of ITMM operators and represents an independent transport problem. Multiple iterative parallel solution methods have investigated, including parallel block Jacobi (PBJ), parallel red/black Gauss-Seidel (PGS), and parallel GMRES (PGMRES). The fastest observed parallel solution method, PGS, was used in a weak scaling comparison with the PARTISN code. Compared to the state-of-the-art SI-KBA with diffusion synthetic acceleration (DSA), this new method without acceleration/preconditioning is not competitive for any problem parameters considered. The best comparisons occur for problems that are difficult for SI DSA, namely highly scattering and optically thick. SI DSA execution time curves are generally steeper than the PGS ones. However, until further testing is performed it cannot be concluded that SI DSA does not outperform the ITMM with PGS even on several thousand or tens of thousands of processors. The PGS method does outperform SI DSA for the periodic heterogeneous layers (PHL) configuration problems. Although this demonstrates a relative strength/weakness between the two methods, the practicality of these problems is much less, further limiting instances where it would be beneficial to select ITMM over SI DSA. The results strongly indicate a need for a robust, stable, and efficient acceleration method (or preconditioner for PGMRES). The spatial multigrid (SMG) method is currently incomplete in that it does not work for all cases considered and does not effectively improve the convergence rate for all values of scattering ratio c or cell dimension h. Nevertheless, it does display the desired trend for highly scattering, optically thin problems. That is, it tends to lower the rate of growth of number of iterations with increasing number of processes, P, while not increasing the number of additional operations per iteration to the extent that the total execution time of the rapidly converging accelerated iterations exceeds that of the slower unaccelerated iterations. A predictive parallel performance model has been developed for the PBJ method. Timing tests were performed such that trend lines could be fitted to the data for the different components and used to estimate the execution times. Applied to the weak scaling results, the model notably underestimates construction time, but combined with a slight overestimation in iterative solution time, the model predicts total execution time very well for large P. It also does a decent job with the strong scaling results, closely predicting the construction time and time per iteration, especially as P increases. Although not shown to be competitive up to 1,024 processing elements with the current state of the art, the parallelized ITMM exhibits promising scaling trends. Ultimately, compared to the KBA method, the parallelized ITMM may be found to be a very attractive option for transport calculations spatially decomposed over several tens of thousands of processes. Acceleration/preconditioning of the parallelized ITMM once developed will improve the convergence rate and improve its competitiveness. (Abstract shortened by UMI.)
NASA Technical Reports Server (NTRS)
Omidvar, K.
1980-01-01
Branching ratios in hydrogen-like atoms due to electric-dipole transitions are tabulated for the initial principal and angular momentum quantum number n, lambda, and final principal and angular momentum quantum numbers n, lambda. In table 1, transition probabilities are given for transitions n, lambda, yields n, where sums have been made with respect to lambda. In this table, 2 or = n' or = 10, o or = lambda' or = n'-1, and 1 or = n or = n'-1. In addition, averages with respect to lambda' and sums with respect to n, and lifetimes are given. In table 2, branching ratios are given for transitions n' lambda' yields ni, where sums have been made with respect to lambda. In these tables, 2 or = n' or = 10, 0 or = lambda', n'-1, and 1 or = n or = n'-1. Averages with respect to lambda' are also given. In table 3, branching ratios are given for transitions n' lambda' yields in lambda, where 1 or = n or = 5, 0 or = lambda or = n-1, n n' or = 15, and 0 or = lambda' or = n(s), where n(s), is the smaller of the two numbers n'-1 and 6. Averages with respect to lambda' are given.
Chatrchyan, S.; Khachatryan, V.; Sirunyan, A. M.; ...
2012-05-31
The Lambda(b) differential production cross section and the cross section ratio anti-Lambda(b)/Lambda(b) are measured as functions of transverse momentum pt(Lambda(b)) and rapidity abs(y(Lambda(b))) in pp collisions at sqrt(s) = 7 TeV using data collected by the CMS experiment at the LHC. The measurements are based on Lambda(b) decays reconstructed in the exclusive final state J/Psi Lambda, with the subsequent decays J/Psi to an opposite-sign muon pair and Lambda to proton pion, using a data sample corresponding to an integrated luminosity of 1.9 inverse femtobarns. The product of the cross section times the branching ratio for Lambda(b) to J/Psi Lambda versusmore » pt(Lambda(b)) falls faster than that of b mesons. The measured value of the cross section times the branching ratio for pt(Lambda(b)) > 10 GeV and abs(y(Lambda(b))) < 2.0 is 1.06 +/- 0.06 +/- 0.12 nb, and the integrated cross section ratio for anti-Lambda(b)/Lambda(b) is 1.02 +/- 0.07 +/- 0.09, where the uncertainties are statistical and systematic, respectively.« less
{lambda}{sub b}{yields}p, {lambda} transition form factors from QCD light-cone sum rules
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wang Yuming; Lue Caidian; Shen Yuelong
2009-10-01
Light-cone sum rules for the {lambda}{sub b}{yields}p, {lambda} transition form factors are derived from the correlation functions expanded by the twist of the distribution amplitudes of the {lambda}{sub b} baryon. In terms of the {lambda}{sub b} three-quark distribution amplitude models constrained by the QCD theory, we calculate the form factors at small momentum transfers and compare the results with those estimated in the conventional light-cone sum rules (LCSR) and perturbative QCD approaches. Our results indicate that the two different versions of sum rules can lead to the consistent numbers of form factors responsible for {lambda}{sub b}{yields}p transition. The {lambda}{sub b}{yields}{lambda}more » transition form factors from LCSR with the asymptotic {lambda} baryon distribution amplitudes are found to be almost 1 order larger than those obtained in the {lambda}{sub b}-baryon LCSR, implying that the preasymptotic corrections to the baryonic distribution amplitudes are of great importance. Moreover, the SU(3) symmetry breaking effects between the form factors f{sub 1}{sup {lambda}{sub b}}{sup {yields}}{sup p} and f{sub 1}{sup {lambda}{sub b}}{sup {yields}}{sup {lambda}} are computed as 28{sub -8}{sup +14}% in the framework of {lambda}{sub b}-baryon LCSR.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Azzurri, P.; Barria, P.; Ciocci, M.A.
The authors present the first observation of the {Lambda}{sub b}{sup 0} {yields} {Lambda}{sub c}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -} decay using data from an integrated luminosity of approximately 2.4 fb{sup -1} of p{bar p} collisions at {radical}s = 1.96 TeV, collected with the CDF II detector at the Fermilab Tevatron. They also present the first observation of the resonant decays {Lambda}{sub b}{sup 0} {yields} {Sigma}{sub c}(2455){sup 0} {pi}{sup +}{pi}{sup -} {yields} {Lambda}{sub c}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -}, {Lambda}{sub b}{sup 0} {yields} {Sigma}{sub c}(2455){sup ++}{pi}{sup -}{pi}{sup -} {yields} {Lambda}{sub c}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -}, {Lambda}{sub b}{sup 0} {yields} {Lambda}{sub c}(2595){sup +}{pi}{sup -}more » {yields} {Lambda}{sub c}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -} and {Lambda}{sub b}{sup 0} {yields} {Lambda}{sub c}(2625){sup +}{pi}{sup -} {yields} {Lambda}{sub c}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -}, and measure their relative branching ratios.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lyuboshitz, V. L.; Lyuboshitz, V. V., E-mail: Valery.Lyuboshitz@jinr.r
2010-05-15
Spin correlations for the {Lambda}{Lambda} and {Lambda}{Lambda}-bar pairs, generated in relativistic heavy-ion collisions, and related angular correlations at the joint registration of hadronic decays of two hyperons, in which space parity is not conserved, are analyzed. The correlation tensor components can be derived from the double angular distribution of products of two decays by the method of 'moments'. The properties of the 'trace' of the correlation tensor (a sum of three diagonal components), determining the relative fractions of the triplet states and singlet state of respective pairs, are discussed. Spin correlations for two identical particles ({Lambda}{Lambda}) and two nonidentical particlesmore » ({Lambda}{Lambda}-bar) are considered from the viewpoint of the conventional model of one-particle sources. In the framework of this model, correlations vanish at sufficiently large relative momenta. However, under these conditions, in the case of two nonidentical particles ({Lambda}{Lambda}-bar) a noticeable role is played by two-particle annihilation (two-quark, two-gluon) sources, which lead to the difference of the correlation tensor from zero. In particular, such a situation may arise when the system passes through the 'mixed phase.'« less
Accelerating the weighted histogram analysis method by direct inversion in the iterative subspace.
Zhang, Cheng; Lai, Chun-Liang; Pettitt, B Montgomery
The weighted histogram analysis method (WHAM) for free energy calculations is a valuable tool to produce free energy differences with the minimal errors. Given multiple simulations, WHAM obtains from the distribution overlaps the optimal statistical estimator of the density of states, from which the free energy differences can be computed. The WHAM equations are often solved by an iterative procedure. In this work, we use a well-known linear algebra algorithm which allows for more rapid convergence to the solution. We find that the computational complexity of the iterative solution to WHAM and the closely-related multiple Bennett acceptance ratio (MBAR) method can be improved by using the method of direct inversion in the iterative subspace. We give examples from a lattice model, a simple liquid and an aqueous protein solution.
NASA Astrophysics Data System (ADS)
Chen, Hao; Lv, Wen; Zhang, Tongtong
2018-05-01
We study preconditioned iterative methods for the linear system arising in the numerical discretization of a two-dimensional space-fractional diffusion equation. Our approach is based on a formulation of the discrete problem that is shown to be the sum of two Kronecker products. By making use of an alternating Kronecker product splitting iteration technique we establish a class of fixed-point iteration methods. Theoretical analysis shows that the new method converges to the unique solution of the linear system. Moreover, the optimal choice of the involved iteration parameters and the corresponding asymptotic convergence rate are computed exactly when the eigenvalues of the system matrix are all real. The basic iteration is accelerated by a Krylov subspace method like GMRES. The corresponding preconditioner is in a form of a Kronecker product structure and requires at each iteration the solution of a set of discrete one-dimensional fractional diffusion equations. We use structure preserving approximations to the discrete one-dimensional fractional diffusion operators in the action of the preconditioning matrix. Numerical examples are presented to illustrate the effectiveness of this approach.
Mizuno, T; Taniguchi, M; Kashiwagi, M; Umeda, N; Tobari, H; Watanabe, K; Dairaku, M; Sakamoto, K; Inoue, T
2010-02-01
Heat load on acceleration grids by secondary particles such as electrons, neutrals, and positive ions, is a key issue for long pulse acceleration of negative ion beams. Complicated behaviors of the secondary particles in multiaperture, multigrid (MAMuG) accelerator have been analyzed using electrostatic accelerator Monte Carlo code. The analytical result is compared to experimental one obtained in a long pulse operation of a MeV accelerator, of which second acceleration grid (A2G) was removed for simplification of structure. The analytical results show that relatively high heat load on the third acceleration grid (A3G) since stripped electrons were deposited mainly on A3G. This heat load on the A3G can be suppressed by installing the A2G. Thus, capability of MAMuG accelerator is demonstrated for suppression of heat load due to secondary particles by the intermediate grids.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cheng, Kwang-Ping; Johnson, Dustin M.; Tarbell, Erik S.
2016-04-15
Lambda Boo-type stars are a group of late B to early F-type Population I dwarfs that show mild to extreme deficiencies of iron-peak elements (up to 2 dex), but their C, N, O, and S abundances are near solar. This intriguing stellar class has recently regained the spotlight because of the directly imaged planets around a confirmed Lambda Boo star, HR 8799, and a suggested Lambda Boo star, Beta Pictoris. The discovery of a giant asteroid belt around Vega, another possible Lambda Boo star, also suggests hidden planets. The possible link between Lambda Boo stars and planet-bearing stars motivates usmore » to study Lambda Boo stars systematically. Since the peculiar nature of the prototype Lambda Boötis was first noticed in 1943, Lambda Boo candidates published in the literature have been selected using widely different criteria. In order to determine the origin of Lambda Boo stars’ unique abundance pattern and to better discriminate between theories explaining the Lambda Boo phenomenon, a consistent working definition of Lambda Boo stars is needed. We have re-evaluated all published Lambda Boo candidates and their available ultraviolet and visible spectra. In this paper, using observed and synthetic spectra, we explore the physical basis for the classification of Lambda Boo stars, and develop quantitative criteria that discriminate metal-poor stars from bona fide Lambda Boo stars. Based on these stricter Lambda Boo classification criteria, we conclude that neither Beta Pictoris nor Vega should be classified as Lambda Boo stars.« less
Kota, V K B; Chavda, N D; Sahu, R
2006-04-01
Interacting many-particle systems with a mean-field one-body part plus a chaos generating random two-body interaction having strength lambda exhibit Poisson to Gaussian orthogonal ensemble and Breit-Wigner (BW) to Gaussian transitions in level fluctuations and strength functions with transition points marked by lambda = lambda c and lambda = lambda F, respectively; lambda F > lambda c. For these systems a theory for the matrix elements of one-body transition operators is available, as valid in the Gaussian domain, with lambda > lambda F, in terms of orbital occupation numbers, level densities, and an integral involving a bivariate Gaussian in the initial and final energies. Here we show that, using a bivariate-t distribution, the theory extends below from the Gaussian regime to the BW regime up to lambda = lambda c. This is well tested in numerical calculations for 6 spinless fermions in 12 single-particle states.
Radioactivity measurements of ITER materials using the TFTR D-T neutron field
NASA Astrophysics Data System (ADS)
Kumar, A.; Abdou, M. A.; Barnes, C. W.; Kugel, H. W.
1994-06-01
The availability of high D-T fusion neutron yields at TFTR has provided a useful opportunity to directly measure D-T neutron-induced radioactivity in a realistic tokamak fusion reactor environment for materials of vital interest to ITER. These measurements are valuable for characterizing radioactivity in various ITER candidate materials, for validating complex neutron transport calculations, and for meeting fusion reactor licensing requirements. The radioactivity measurements at TFTR involve potential ITER materials including stainless steel 316, vanadium, titanium, chromium, silicon, iron, cobalt, nickel, molybdenum, aluminum, copper, zinc, zirconium, niobium, and tungsten. Small samples of these materials were irradiated close to the plasma and just outside the vacuum vessel wall of TFTR, locations of different neutron energy spectra. Saturation activities for both threshold and capture reactions were measured. Data from dosimetric reactions have been used to obtain preliminary neutron energy spectra. Spectra from the first wall were compared to calculations from ITER and to measurements from accelerator-based tests.
2011-12-01
of residuals versus iteration number. “ Intermit ” and “retheta” are turbulence parameters for turbulence intermittency and . 42 ix Figure 4-7 – Wall...is based on the fact that “the flow‐field adapts at a very fast rate to changes in the free stream conditions as the vehicle is accelerating. This...4‐6 – Example of residuals versus iteration number. “ Intermit ” and “retheta” are turbulence parameters for turbulence intermittency and
NASA Astrophysics Data System (ADS)
Cheng, Hok-Chuen
This thesis summaries the measurements of correlations between Lambda 0Lambda0, Lambda0Lambda 0, and Lambda0Lambda 0 hyperon pairs produced inclusively at the LHC, which are useful for a better understanding of the quark-antiquark pair production and jet fragmentation and hadronization processes. The analysis is based on hyperon pairs selected using the muon and minimum bias data samples collected at the ATLAS experiment from proton-proton collisions at a center-of-mass energy of 7 TeV in 2010. Excess Lambda0Lambda 0 are observed near the production threshold and are identified to be originated from the parton system in the string model in the MC sample, decaying either directly or through heavy strange resonances such as Sigma0 and Sigma*(1385). Dynamical correlations have been explored through a correlation function defined as the ratio of two-particle to single-particle densities. Positive correlation is observed for Lambda0Lambda0 and anticorrelation is observed for Lambda0Lambda 0 and Lambda0Lambda 0 for Q in [0,2] GeV. The structure replicates similar correlations in pp, pp, and pppp events in PYTHIA generator as predicted by the Lund string fragmentation model. Parameters of the "popcorn" mechanism implemented in the PYTHIA generator are tuned and are found to have little impact on the structure observed. The spin composition of the sample is extracted using a data-driven reference sample built by event mixing. Appropriate corrections have been made to the kinematic distributions in the reference sample by kinematic weighting to make sure that the detector effects are well modeled. A modified Pearson's chi2 test statistics is calculated for the costheta* distribution to determine the best-fitted A-value for data. The results are consistent with zero for both like-type and unlike-type hyperon pairs in Q ∈ [0,10] GeV and Q ∈ [1,10] GeV respectively. The data statistics in the range of Q ∈ [0, 1] GeV is currently too low for the estimation of the emitter size for Fermi-Dirac correlation.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Akaishi, Yoshinori; College of Science and Technology, Nihon University, Funabashi 274-8501; Myint, Khin Swe
The overbinding problem of {sub {lambda}}{sup 5}He is solved by introducing a concept of coherent {lambda}-{sigma} coupling which is equivalent to a {lambda}NN three-body force. This three-body force is coherently enhanced in the 0{sup +} states of {sub {lambda}}{sup 4}H and {sub {lambda}}{sup 4}He. The 0{sup +}-1{sup +} splitting in these hypernuclei is mainly due to coherent {lambda}-{sigma} coupling and partly due to the {lambda}N spin-spin interaction. A {lambda}NN three-body potential is derived from the coupled-channel treatment. The origin of the repulsive and attractive nature of the three-body force is discussed. Coherent {lambda}-{sigma} coupling becomes more important in neutron-rich hypernucleimore » and especially in neutron-star matter at high densities. The possible existence of ''hyperheavy hydrogen'', {sub {lambda}}{sup 6}H, is suggested.« less
NASA Technical Reports Server (NTRS)
Carpenter, Kenneth G.; Robinson, Richard D.; Harper, Graham M.; Bennett, Philip D.; Brown, Alexander; Mullan, Dermott J.
1999-01-01
UV spectra of lambda Velorum taken with the Goddard High Resolution Spectrograph (GHRS) on the Hubble Space Telescope are used to probe the structure of the outer atmospheric layers and wind and to estimate the mass-loss rate from this K5 lb-II supergiant. VLA radio observations at lambda = 3.6 cm are used to obtain an independent check on the wind velocity and mass-loss rate inferred from the UV observations, Parameters of the chromospheric structure are estimated from measurements of UV line widths, positions, and fluxes and from the UV continuum flux distribution. The ratios of optically thin C II] emission lines indicate a mean chromospheric electron density of log N(sub e) approximately equal 8.9 +/- 0.2 /cc. The profiles of these lines indicate a chromospheric turbulence (v(sub 0) approximately equal 25-36 km/s), which greatly exceeds that seen in either the photosphere or wind. The centroids of optically thin emission lines of Fe II and of the emission wings of self-reversed Fe II lines indicate that they are formed in plasma approximately at rest with respect to the photosphere of the star. This suggests that the acceleration of the wind occurs above the chromospheric regions in which these emission line photons are created. The UV continuum detected by the GHRS clearly traces the mean flux-formation temperature as it increases with height in the chromosphere from a well-defined temperature minimum of 3200 K up to about 4600 K. Emission seen in lines of C III] and Si III] provides evidence of material at higher than chromospheric temperatures in the outer atmosphere of this noncoronal star. The photon-scattering wind produces self-reversals in the strong chromospheric emission lines, which allow us to probe the velocity field of the wind. The velocities to which these self-absorptions extend increase with intrinsic line strength, and thus height in the wind, and therefore directly map the wind acceleration. The width and shape of these self-absorptions reflect a wind turbulence of approximately equal 9-21 km/s. We further characterize the wind by comparing the observations with synthetic profiles generated with the Lamers et al. Sobolev with Exact Integration (SEI) radiative transfer code, assuming simple models of the outer atmospheric structure. These comparisons indicate that the wind in 1994 can be described by a model with a wind acceleration parameter beta approximately 0.9, a terminal velocity of 29-33 km/s, and a mass-loss rate approximately 3 x 10(exp -9) solar M/yr. Modeling of the 3.6 cm radio flux observed in 1997 suggests a more slowly accelerating wind (higher beta) and/or a higher mass-loss rate than inferred from the UV line profiles. These differences may be due to temporal variations in the wind or from limitations in one or both of the models. The discrepancy is currently under investigation.
Osipiuk, J; Zylicz, M
1991-01-01
Initiation of replication of lambda DNA requires assembly of the proper nucleoprotein complex consisting of the lambda origin of replication-lambda O-lambda P-dnaB proteins. The dnaJ, dnaK and grpE heat shock proteins destabilize the lambda P-dnaB interaction in this complex permitting dnaB helicase to unwind lambda DNA near ori lambda sequence. First step of this disassembling reaction is the binding of dnaK protein to lambda P protein. In this report we examined the influence of dnaJ and grpE proteins on stability of the lambda P-dnaK complex. Our results show that grpE alone dissociates this complex, but both grpE and dnaJ together do not. These results suggest that, in the presence of grpE protein, dnaK protein has a higher affinity for lambda P protein complexed with dnaJ protein than in the situation where grpE protein is not used.
Abulencia, A; Adelman, J; Affolder, T; Akimoto, T; Albrow, M G; Ambrose, D; Amerio, S; Amidei, D; Anastassov, A; Anikeev, K; Annovi, A; Antos, J; Aoki, M; Apollinari, G; Arguin, J-F; Arisawa, T; Artikov, A; Ashmanskas, W; Attal, A; Azfar, F; Azzi-Bacchetta, P; Azzurri, P; Bacchetta, N; Badgett, W; Barbaro-Galtieri, A; Barnes, V E; Barnett, B A; Baroiant, S; Bartsch, V; Bauer, G; Bedeschi, F; Behari, S; Belforte, S; Bellettini, G; Bellinger, J; Belloni, A; Benjamin, D; Beretvas, A; Beringer, J; Berry, T; Bhatti, A; Binkley, M; Bisello, D; Blair, R E; Blocker, C; Blumenfeld, B; Bocci, A; Bodek, A; Boisvert, V; Bolla, G; Bolshov, A; Bortoletto, D; Boudreau, J; Boveia, A; Brau, B; Brigliadori, L; Bromberg, C; Brubaker, E; Budagov, J; Budd, H S; Budd, S; Budroni, S; Burkett, K; Busetto, G; Bussey, P; Byrum, K L; Cabrera, S; Campanelli, M; Campbell, M; Canelli, F; Canepa, A; Carillo, S; Carlsmith, D; Carosi, R; Casarsa, M; Castro, A; Catastini, P; Cauz, D; Cavalli-Sforza, M; Cerri, A; Cerrito, L; Chang, S H; Chen, Y C; Chertok, M; Chiarelli, G; Chlachidze, G; Chlebana, F; Cho, I; Cho, K; Chokheli, D; Chou, J P; Choudalakis, G; Chuang, S H; Chung, K; Chung, W H; Chung, Y S; Ciljak, M; Ciobanu, C I; Ciocci, M A; Clark, A; Clark, D; Coca, M; Compostella, G; Convery, M E; Conway, J; Cooper, B; Copic, K; Cordelli, M; Cortiana, G; Crescioli, F; Cuenca Almenar, C; Cuevas, J; Culbertson, R; Cully, J C; Cyr, D; DaRonco, S; D'Auria, S; Davies, T; D'Onofrio, M; Dagenhart, D; de Barbaro, P; De Cecco, S; Deisher, A; De Lentdecker, G; Dell'Orso, M; Delli Paoli, F; Demortier, L; Deng, J; Deninno, M; De Pedis, D; Derwent, P F; Di Giovanni, G P; Dionisi, C; Di Ruzza, B; Dittmann, J R; DiTuro, P; Dörr, C; Donati, S; Donega, M; Dong, P; Donini, J; Dorigo, T; Dube, S; Efron, J; Erbacher, R; Errede, D; Errede, S; Eusebi, R; Fang, H C; Farrington, S; Fedorko, I; Fedorko, W T; Feild, R G; Feindt, M; Fernandez, J P; Field, R; Flanagan, G; Foland, A; Forrester, S; Foster, G W; Franklin, M; Freeman, J C; Furic, I; Gallinaro, M; Galyardt, J; Garcia, J E; Garberson, F; Garfinkel, A F; Gay, C; Gerberich, H; Gerdes, D; Giagu, S; Giannetti, P; Gibson, A; Gibson, K; Gimmell, J L; Ginsburg, C; Giokaris, N; Giordani, M; Giromini, P; Giunta, M; Giurgiu, G; Glagolev, V; Glenzinski, D; Gold, M; Goldschmidt, N; Goldstein, J; Gomez, G; Gomez-Ceballos, G; Goncharov, M; González, O; Gorelov, I; Goshaw, A T; Goulianos, K; Gresele, A; Griffiths, M; Grinstein, S; Grosso-Pilcher, C; Group, R C; Grundler, U; Guimaraes da Costa, J; Gunay-Unalan, Z; Haber, C; Hahn, K; Hahn, S R; Halkiadakis, E; Hamilton, A; Han, B-Y; Han, J Y; Handler, R; Happacher, F; Hara, K; Hare, M; Harper, S; Harr, R F; Harris, R M; Hartz, M; Hatakeyama, K; Hauser, J; Heijboer, A; Heinemann, B; Heinrich, J; Henderson, C; Herndon, M; Heuser, J; Hidas, D; Hill, C S; Hirschbuehl, D; Hocker, A; Holloway, A; Hou, S; Houlden, M; Hsu, S-C; Huffman, B T; Hughes, R E; Husemann, U; Huston, J; Incandela, J; Introzzi, G; Iori, M; Ishizawa, Y; Ivanov, A; Iyutin, B; James, E; Jang, D; Jayatilaka, B; Jeans, D; Jensen, H; Jeon, E J; Jindariani, S; Jones, M; Joo, K K; Jun, S Y; Jung, J E; Junk, T R; Kamon, T; Karchin, P E; Kato, Y; Kemp, Y; Kephart, R; Kerzel, U; Khotilovich, V; Kilminster, B; Kim, D H; Kim, H S; Kim, J E; Kim, M J; Kim, S B; Kim, S H; Kim, Y K; Kimura, N; Kirsch, L; Klimenko, S; Klute, M; Knuteson, B; Ko, B R; Kondo, K; Kong, D J; Konigsberg, J; Korytov, A; Kotwal, A V; Kovalev, A; Kraan, A C; Kraus, J; Kravchenko, I; Kreps, M; Kroll, J; Krumnack, N; Kruse, M; Krutelyov, V; Kubo, T; Kuhlmann, S E; Kuhr, T; Kusakabe, Y; Kwang, S; Laasanen, A T; Lai, S; Lami, S; Lammel, S; Lancaster, M; Lander, R L; Lannon, K; Lath, A; Latino, G; Lazzizzera, I; Le, Y; LeCompte, T; Lee, J; Lee, J; Lee, Y J; Lee, S W; Lefèvre, R; Leonardo, N; Leone, S; Levy, S; Lewis, J D; Lin, C; Lin, C S; Lindgren, M; Lipeles, E; Lister, A; Litvintsev, D O; Liu, T; Lockyer, N S; Loginov, A; Loreti, M; Loverre, P; Lu, R-S; Lucchesi, D; Lujan, P; Lukens, P; Lungu, G; Lyons, L; Lys, J; Lysak, R; Lytken, E; Mack, P; MacQueen, D; Madrak, R; Maeshima, K; Makhoul, K; Maki, T; Maksimovic, P; Malde, S; Manca, G; Margaroli, F; Marginean, R; Marino, C; Marino, C P; Martin, A; Martin, M; Martin, V; Martínez, M; Maruyama, T; Mastrandrea, P; Masubuchi, T; Matsunaga, H; Mattson, M E; Mazini, R; Mazzanti, P; McFarland, K S; McIntyre, P; McNulty, R; Mehta, A; Mehtala, P; Menzemer, S; Menzione, A; Merkel, P; Mesropian, C; Messina, A; Miao, T; Miladinovic, N; Miles, J; Miller, R; Mills, C; Milnik, M; Mitra, A; Mitselmakher, G; Miyamoto, A; Moed, S; Moggi, N; Mohr, B; Moore, R; Morello, M; Movilla Fernandez, P; Mülmenstädt, J; Mukherjee, A; Muller, Th; Mumford, R; Murat, P; Nachtman, J; Nagano, A; Naganoma, J; Nakano, I; Napier, A; Necula, V; Neu, C; Neubauer, M S; Nielsen, J; Nigmanov, T; Nodulman, L; Norniella, O; Nurse, E; Oh, S H; Oh, Y D; Oksuzian, I; Okusawa, T; Oldeman, R; Orava, R; Osterberg, K; Pagliarone, C; Palencia, E; Papadimitriou, V; Paramonov, A A; Parks, B; Pashapour, S; Patrick, J; Pauletta, G; Paulini, M; Paus, C; Pellett, D E; Penzo, A; Phillips, T J; Piacentino, G; Piedra, J; Pinera, L; Pitts, K; Plager, C; Pondrom, L; Portell, X; Poukhov, O; Pounder, N; Prakoshyn, F; Pronko, A; Proudfoot, J; Ptohos, F; Punzi, G; Pursley, J; Rademacker, J; Rahaman, A; Ranjan, N; Rappoccio, S; Reisert, B; Rekovic, V; Renton, P; Rescigno, M; Richter, S; Rimondi, F; Ristori, L; Robson, A; Rodrigo, T; Rogers, E; Rolli, S; Roser, R; Rossi, M; Rossin, R; Ruiz, A; Russ, J; Rusu, V; Saarikko, H; Sabik, S; Safonov, A; Sakumoto, W K; Salamanna, G; Saltó, O; Saltzberg, D; Sánchez, C; Santi, L; Sarkar, S; Sartori, L; Sato, K; Savard, P; Savoy-Navarro, A; Scheidle, T; Schlabach, P; Schmidt, E E; Schmidt, M P; Schmitt, M; Schwarz, T; Scodellaro, L; Scott, A L; Scribano, A; Scuri, F; Sedov, A; Seidel, S; Seiya, Y; Semenov, A; Sexton-Kennedy, L; Sfyrla, A; Shapiro, M D; Shears, T; Shepard, P F; Sherman, D; Shimojima, M; Shochet, M; Shon, Y; Shreyber, I; Sidoti, A; Sinervo, P; Sisakyan, A; Sjolin, J; Slaughter, A J; Slaunwhite, J; Sliwa, K; Smith, J R; Snider, F D; Snihur, R; Soderberg, M; Soha, A; Somalwar, S; Sorin, V; Spalding, J; Spinella, F; Spreitzer, T; Squillacioti, P; Stanitzki, M; Staveris-Polykalas, A; St Denis, R; Stelzer, B; Stelzer-Chilton, O; Stentz, D; Strologas, J; Stuart, D; Suh, J S; Sukhanov, A; Sun, H; Suzuki, T; Taffard, A; Takashima, R; Takeuchi, Y; Takikawa, K; Tanaka, M; Tanaka, R; Tecchio, M; Teng, P K; Terashi, K; Thom, J; Thompson, A S; Thomson, E; Tipton, P; Tiwari, V; Tkaczyk, S; Toback, D; Tokar, S; Tollefson, K; Tomura, T; Tonelli, D; Torre, S; Torretta, D; Tourneur, S; Trischuk, W; Tseng, J; Tsuchiya, R; Tsuno, S; Turini, N; Ukegawa, F; Unverhau, T; Uozumi, S; Usynin, D; Vallecorsa, S; van Remortel, N; Varganov, A; Vataga, E; Vázquez, F; Velev, G; Veramendi, G; Veszpremi, V; Vidal, R; Vila, I; Vilar, R; Vine, T; Vollrath, I; Volobouev, I; Volpi, G; Würthwein, F; Wagner, P; Wagner, R G; Wagner, R L; Wagner, J; Wagner, W; Wallny, R; Wang, S M; Warburton, A; Waschke, S; Waters, D; Wester, W C; Whitehouse, B; Whiteson, D; Wicklund, A B; Wicklund, E; Williams, G; Williams, H H; Wilson, P; Winer, B L; Wittich, P; Wolbers, S; Wolfe, C; Wright, T; Wu, X; Wynne, S M; Yagil, A; Yamamoto, K; Yamaoka, J; Yamashita, T; Yang, C; Yang, U K; Yang, Y C; Yao, W M; Yeh, G P; Yoh, J; Yorita, K; Yoshida, T; Yu, G B; Yu, I; Yu, S S; Yun, J C; Zanello, L; Zanetti, A; Zaw, I; Zhang, X; Zhou, J; Zucchelli, S
2007-03-23
We present the first observation of the baryon decay Lambda b0-->Lambda c+pi- followed by Lambda c+-->pK-pi+ in 106 pb-1 pp collisions at square root s=1.96 TeV in the CDF experiment. In order to reduce systematic error, the measured rate for Lambda b0 decay is normalized to the kinematically similar meson decay B0-->D+pi- followed by D+-->pi+K-pi+. We report the ratio of production cross sections (sigma) times the ratio of branching fractions (B) for the momentum region integrated above pT>6 GeV/c and pseudorapidity range |eta|<1.3: sigma(pp-->Lambda b0X)/sigma(pp-->B0X)xB(Lambda b0-->Lambda c+pi-)/B(B0-->D+pi-)=0.82+/-0.08(stat)+/-0.11(syst)+/-0.22[B(Lambda c+-->pK-pi+)].
Stability analysis of a deterministic dose calculation for MRI-guided radiotherapy.
Zelyak, O; Fallone, B G; St-Aubin, J
2017-12-14
Modern effort in radiotherapy to address the challenges of tumor localization and motion has led to the development of MRI guided radiotherapy technologies. Accurate dose calculations must properly account for the effects of the MRI magnetic fields. Previous work has investigated the accuracy of a deterministic linear Boltzmann transport equation (LBTE) solver that includes magnetic field, but not the stability of the iterative solution method. In this work, we perform a stability analysis of this deterministic algorithm including an investigation of the convergence rate dependencies on the magnetic field, material density, energy, and anisotropy expansion. The iterative convergence rate of the continuous and discretized LBTE including magnetic fields is determined by analyzing the spectral radius using Fourier analysis for the stationary source iteration (SI) scheme. The spectral radius is calculated when the magnetic field is included (1) as a part of the iteration source, and (2) inside the streaming-collision operator. The non-stationary Krylov subspace solver GMRES is also investigated as a potential method to accelerate the iterative convergence, and an angular parallel computing methodology is investigated as a method to enhance the efficiency of the calculation. SI is found to be unstable when the magnetic field is part of the iteration source, but unconditionally stable when the magnetic field is included in the streaming-collision operator. The discretized LBTE with magnetic fields using a space-angle upwind stabilized discontinuous finite element method (DFEM) was also found to be unconditionally stable, but the spectral radius rapidly reaches unity for very low-density media and increasing magnetic field strengths indicating arbitrarily slow convergence rates. However, GMRES is shown to significantly accelerate the DFEM convergence rate showing only a weak dependence on the magnetic field. In addition, the use of an angular parallel computing strategy is shown to potentially increase the efficiency of the dose calculation.
Stability analysis of a deterministic dose calculation for MRI-guided radiotherapy
NASA Astrophysics Data System (ADS)
Zelyak, O.; Fallone, B. G.; St-Aubin, J.
2018-01-01
Modern effort in radiotherapy to address the challenges of tumor localization and motion has led to the development of MRI guided radiotherapy technologies. Accurate dose calculations must properly account for the effects of the MRI magnetic fields. Previous work has investigated the accuracy of a deterministic linear Boltzmann transport equation (LBTE) solver that includes magnetic field, but not the stability of the iterative solution method. In this work, we perform a stability analysis of this deterministic algorithm including an investigation of the convergence rate dependencies on the magnetic field, material density, energy, and anisotropy expansion. The iterative convergence rate of the continuous and discretized LBTE including magnetic fields is determined by analyzing the spectral radius using Fourier analysis for the stationary source iteration (SI) scheme. The spectral radius is calculated when the magnetic field is included (1) as a part of the iteration source, and (2) inside the streaming-collision operator. The non-stationary Krylov subspace solver GMRES is also investigated as a potential method to accelerate the iterative convergence, and an angular parallel computing methodology is investigated as a method to enhance the efficiency of the calculation. SI is found to be unstable when the magnetic field is part of the iteration source, but unconditionally stable when the magnetic field is included in the streaming-collision operator. The discretized LBTE with magnetic fields using a space-angle upwind stabilized discontinuous finite element method (DFEM) was also found to be unconditionally stable, but the spectral radius rapidly reaches unity for very low-density media and increasing magnetic field strengths indicating arbitrarily slow convergence rates. However, GMRES is shown to significantly accelerate the DFEM convergence rate showing only a weak dependence on the magnetic field. In addition, the use of an angular parallel computing strategy is shown to potentially increase the efficiency of the dose calculation.
Corrigendum to "Stability analysis of a deterministic dose calculation for MRI-guided radiotherapy".
Zelyak, Oleksandr; Fallone, B Gino; St-Aubin, Joel
2018-03-12
Modern effort in radiotherapy to address the challenges of tumor localization and motion has led to the development of MRI guided radiotherapy technologies. Accurate dose calculations must properly account for the effects of the MRI magnetic fields. Previous work has investigated the accuracy of a deterministic linear Boltzmann transport equation (LBTE) solver that includes magnetic field, but not the stability of the iterative solution method. In this work, we perform a stability analysis of this deterministic algorithm including an investigation of the convergence rate dependencies on the magnetic field, material density, energy, and anisotropy expansion. The iterative convergence rate of the continuous and discretized LBTE including magnetic fields is determined by analyzing the spectral radius using Fourier analysis for the stationary source iteration (SI) scheme. The spectral radius is calculated when the magnetic field is included (1) as a part of the iteration source, and (2) inside the streaming-collision operator. The non-stationary Krylov subspace solver GMRES is also investigated as a potential method to accelerate the iterative convergence, and an angular parallel computing methodology is investigated as a method to enhance the efficiency of the calculation. SI is found to be unstable when the magnetic field is part of the iteration source, but unconditionally stable when the magnetic field is included in the streaming-collision operator. The discretized LBTE with magnetic fields using a space-angle upwind stabilized discontinuous finite element method (DFEM) was also found to be unconditionally stable, but the spectral radius rapidly reaches unity for very low density media and increasing magnetic field strengths indicating arbitrarily slow convergence rates. However, GMRES is shown to significantly accelerate the DFEM convergence rate showing only a weak dependence on the magnetic field. In addition, the use of an angular parallel computing strategy is shown to potentially increase the efficiency of the dose calculation. © 2018 Institute of Physics and Engineering in Medicine.
Twin-Screw Extruder Development for the ITER Pellet Injection System
DOE Office of Scientific and Technical Information (OSTI.GOV)
Meitner, Steven J; Baylor, Larry R; Combs, Stephen Kirk
The ITER pellet injection system is comprised of devices to form and accelerate pellets, and will be connected to inner wall guide tubes for fueling, and outer wall guide tubes for ELM pacing. An extruder will provide a stream of solid hydrogen isotopes to a secondary section, where pellets are cut and accelerated with a gas gun into the plasma. The ITER pellet injection system is required to provide a plasma fueling rate of 120 Pa-m3/s (900 mbar-L/s) and durations of up to 3000 s. The fueling pellets will be injected at a rate up to 10 Hz and pelletsmore » used to trigger ELMs will be injected at higher rates up to 20 Hz. A twin-screw extruder for the ITER pellet injection system is under development at the Oak Ridge National Laboratory. A one-fifth ITER scale prototype has been built and has demonstrated the production of a continuous solid deuterium extrusion. The 27 mm diameter, intermeshed, counter-rotating extruder screws are rotated at a rate up to ≈5 rpm. Deuterium gas is pre-cooled and liquefied and solidified in separate extruder barrels. The precooler consists of a deuterium gas filled copper coil suspended in a separate stainless steel vessel containing liquid nitrogen. The liquefier is comprised of a copper barrel connected to a Cryomech AL330 cryocooler, which has a machined helical groove surrounded by a copper jacket, through which the pre-cooled deuterium condenses. The lower extruder barrel is connected to a Cryomech GB-37 cryocooler to solidify the deuterium (at ≈15 K) before it is forced through the extruder die. The die forms the extrusion to a 3 mm x 4 mm rectangular cross section. Design improvements have been made to improve the pre-cooler and liquefier heat exchangers, to limit the loss of extrusion through gaps in the screws. This paper will describe the design improvements for the next iteration of the extruder prototype.« less
Undersampling strategies for compressed sensing accelerated MR spectroscopic imaging
NASA Astrophysics Data System (ADS)
Vidya Shankar, Rohini; Hu, Houchun Harry; Bikkamane Jayadev, Nutandev; Chang, John C.; Kodibagkar, Vikram D.
2017-03-01
Compressed sensing (CS) can accelerate magnetic resonance spectroscopic imaging (MRSI), facilitating its widespread clinical integration. The objective of this study was to assess the effect of different undersampling strategy on CS-MRSI reconstruction quality. Phantom data were acquired on a Philips 3 T Ingenia scanner. Four types of undersampling masks, corresponding to each strategy, namely, low resolution, variable density, iterative design, and a priori were simulated in Matlab and retrospectively applied to the test 1X MRSI data to generate undersampled datasets corresponding to the 2X - 5X, and 7X accelerations for each type of mask. Reconstruction parameters were kept the same in each case(all masks and accelerations) to ensure that any resulting differences can be attributed to the type of mask being employed. The reconstructed datasets from each mask were statistically compared with the reference 1X, and assessed using metrics like the root mean square error and metabolite ratios. Simulation results indicate that both the a priori and variable density undersampling masks maintain high fidelity with the 1X up to five-fold acceleration. The low resolution mask based reconstructions showed statistically significant differences from the 1X with the reconstruction failing at 3X, while the iterative design reconstructions maintained fidelity with the 1X till 4X acceleration. In summary, a pilot study was conducted to identify an optimal sampling mask in CS-MRSI. Simulation results demonstrate that the a priori and variable density masks can provide statistically similar results to the fully sampled reference. Future work would involve implementing these two masks prospectively on a clinical scanner.
Improved Convergence and Robustness of USM3D Solutions on Mixed-Element Grids
NASA Technical Reports Server (NTRS)
Pandya, Mohagna J.; Diskin, Boris; Thomas, James L.; Frink, Neal T.
2016-01-01
Several improvements to the mixed-element USM3D discretization and defect-correction schemes have been made. A new methodology for nonlinear iterations, called the Hierarchical Adaptive Nonlinear Iteration Method, has been developed and implemented. The Hierarchical Adaptive Nonlinear Iteration Method provides two additional hierarchies around a simple and approximate preconditioner of USM3D. The hierarchies are a matrix-free linear solver for the exact linearization of Reynolds-averaged Navier-Stokes equations and a nonlinear control of the solution update. Two variants of the Hierarchical Adaptive Nonlinear Iteration Method are assessed on four benchmark cases, namely, a zero-pressure-gradient flat plate, a bump-in-channel configuration, the NACA 0012 airfoil, and a NASA Common Research Model configuration. The new methodology provides a convergence acceleration factor of 1.4 to 13 over the preconditioner-alone method representing the baseline solver technology.
Improved Convergence and Robustness of USM3D Solutions on Mixed-Element Grids
NASA Technical Reports Server (NTRS)
Pandya, Mohagna J.; Diskin, Boris; Thomas, James L.; Frinks, Neal T.
2016-01-01
Several improvements to the mixed-elementUSM3Ddiscretization and defect-correction schemes have been made. A new methodology for nonlinear iterations, called the Hierarchical Adaptive Nonlinear Iteration Method, has been developed and implemented. The Hierarchical Adaptive Nonlinear Iteration Method provides two additional hierarchies around a simple and approximate preconditioner of USM3D. The hierarchies are a matrix-free linear solver for the exact linearization of Reynolds-averaged Navier-Stokes equations and a nonlinear control of the solution update. Two variants of the Hierarchical Adaptive Nonlinear Iteration Method are assessed on four benchmark cases, namely, a zero-pressure-gradient flat plate, a bump-in-channel configuration, the NACA 0012 airfoil, and a NASA Common Research Model configuration. The new methodology provides a convergence acceleration factor of 1.4 to 13 over the preconditioner-alone method representing the baseline solver technology.
NASA Astrophysics Data System (ADS)
Trujillo Bueno, J.; Fabiani Bendicho, P.
1995-12-01
Iterative schemes based on Gauss-Seidel (G-S) and optimal successive over-relaxation (SOR) iteration are shown to provide a dramatic increase in the speed with which non-LTE radiation transfer (RT) problems can be solved. The convergence rates of these new RT methods are identical to those of upper triangular nonlocal approximate operator splitting techniques, but the computing time per iteration and the memory requirements are similar to those of a local operator splitting method. In addition to these properties, both methods are particularly suitable for multidimensional geometry, since they neither require the actual construction of nonlocal approximate operators nor the application of any matrix inversion procedure. Compared with the currently used Jacobi technique, which is based on the optimal local approximate operator (see Olson, Auer, & Buchler 1986), the G-S method presented here is faster by a factor 2. It gives excellent smoothing of the high-frequency error components, which makes it the iterative scheme of choice for multigrid radiative transfer. This G-S method can also be suitably combined with standard acceleration techniques to achieve even higher performance. Although the convergence rate of the optimal SOR scheme developed here for solving non-LTE RT problems is much higher than G-S, the computing time per iteration is also minimal, i.e., virtually identical to that of a local operator splitting method. While the conventional optimal local operator scheme provides the converged solution after a total CPU time (measured in arbitrary units) approximately equal to the number n of points per decade of optical depth, the time needed by this new method based on the optimal SOR iterations is only √n/2√2. This method is competitive with those that result from combining the above-mentioned Jacobi and G-S schemes with the best acceleration techniques. Contrary to what happens with the local operator splitting strategy currently in use, these novel methods remain effective even under extreme non-LTE conditions in very fine grids.
Stable carbon isotope fractionation during the biodegradation of lambda-cyhalothrin.
Shen, Xiaoli; Xu, Zemin; Zhang, Xichang; Yang, Fangxing
2015-11-01
In this study, the microbial degradation of lambda-cyhalothrin in soil was investigated using compound-specific stable isotope analysis. The results revealed that lambda-cyhalothrin was biodegraded in soil under laboratory conditions. The half-lives of lambda-cyhalothrin were determined to be 49 and 161 days in non-sterile and sterile soils spiked with 2mg/kg lambda-cyhalothrin and 84 and 154 days in non-sterile and sterile soils spiked with 10mg/kg lambda-cyhalothrin, respectively. The biodegradation of lambda-cyhalothrin resulted in carbon isotope fractionation, which shifted from -29.0‰ to -26.5‰ in soil spiked with 2mg/kg lambda-cyhalothrin, and to -27.5‰ with 10mg/kg lambda-cyhalothrin. A relationship was established between the stable carbon isotope fraction and the residual concentrations of lambda-cyhalothrin by the Rayleigh equation in which the carbon isotope enrichment factor ε of the microbial degradation of lambda-cyhalothrin in the soil was calculated as -2.53‰. This study provides an approach to quantitatively evaluate the biodegradation of lambda-cyhalothrin in soil in field studies. Copyright © 2015 Elsevier B.V. All rights reserved.
Dynamics of a family of transcendental meromorphic functions having rational Schwarzian derivative
NASA Astrophysics Data System (ADS)
Sajid, M.; Kapoor, G. P.
2007-02-01
In the present paper, a class of critically finite transcendental meromorphic functions having rational Schwarzian derivative is introduced and the dynamics of functions in one parameter family is investigated. It is found that there exist two parameter values [lambda]*=[phi](0)>0 and , where and is the real root of [phi]'(x)=0, such that the Fatou sets of f[lambda](z) for [lambda]=[lambda]* and [lambda]=[lambda]** contain parabolic domains. A computationally useful characterization of the Julia set of the function f[lambda](z) as the complement of the basin of attraction of an attracting real fixed point of f[lambda](z) is established and applied for the generation of the images of the Julia sets of f[lambda](z). Further, it is observed that the Julia set of explodes to whole complex plane for [lambda]>[lambda]**. Finally, our results found in the present paper are compared with the recent results on dynamics of one parameter families [lambda]tanz, [R.L. Devaney, L. Keen, Dynamics of meromorphic maps: Maps with polynomial Schwarzian derivative, Ann. Sci. Ecole Norm. Sup. 22 (4) (1989) 55-79; L. Keen, J. Kotus, Dynamics of the family [lambda]tan(z), Conform. Geom. Dynam. 1 (1997) 28-57; G.M. Stallard, The Hausdorff dimension of Julia sets of meromorphic functions, J. London Math. Soc. 49 (1994) 281-295] and , [lambda]>0 [G.P. Kapoor, M. Guru Prem Prasad, Dynamics of : The Julia set and bifurcation, Ergodic Theory Dynam. Systems 18 (1998) 1363-1383].
An assessment of coupling algorithms for nuclear reactor core physics simulations
Hamilton, Steven; Berrill, Mark; Clarno, Kevin; ...
2016-04-01
This paper evaluates the performance of multiphysics coupling algorithms applied to a light water nuclear reactor core simulation. The simulation couples the k-eigenvalue form of the neutron transport equation with heat conduction and subchannel flow equations. We compare Picard iteration (block Gauss–Seidel) to Anderson acceleration and multiple variants of preconditioned Jacobian-free Newton–Krylov (JFNK). The performance of the methods are evaluated over a range of energy group structures and core power levels. A novel physics-based approximation to a Jacobian-vector product has been developed to mitigate the impact of expensive on-line cross section processing steps. Furthermore, numerical simulations demonstrating the efficiency ofmore » JFNK and Anderson acceleration relative to standard Picard iteration are performed on a 3D model of a nuclear fuel assembly. Both criticality (k-eigenvalue) and critical boron search problems are considered.« less
An assessment of coupling algorithms for nuclear reactor core physics simulations
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hamilton, Steven; Berrill, Mark; Clarno, Kevin
This paper evaluates the performance of multiphysics coupling algorithms applied to a light water nuclear reactor core simulation. The simulation couples the k-eigenvalue form of the neutron transport equation with heat conduction and subchannel flow equations. We compare Picard iteration (block Gauss–Seidel) to Anderson acceleration and multiple variants of preconditioned Jacobian-free Newton–Krylov (JFNK). The performance of the methods are evaluated over a range of energy group structures and core power levels. A novel physics-based approximation to a Jacobian-vector product has been developed to mitigate the impact of expensive on-line cross section processing steps. Furthermore, numerical simulations demonstrating the efficiency ofmore » JFNK and Anderson acceleration relative to standard Picard iteration are performed on a 3D model of a nuclear fuel assembly. Both criticality (k-eigenvalue) and critical boron search problems are considered.« less
An assessment of coupling algorithms for nuclear reactor core physics simulations
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hamilton, Steven, E-mail: hamiltonsp@ornl.gov; Berrill, Mark, E-mail: berrillma@ornl.gov; Clarno, Kevin, E-mail: clarnokt@ornl.gov
This paper evaluates the performance of multiphysics coupling algorithms applied to a light water nuclear reactor core simulation. The simulation couples the k-eigenvalue form of the neutron transport equation with heat conduction and subchannel flow equations. We compare Picard iteration (block Gauss–Seidel) to Anderson acceleration and multiple variants of preconditioned Jacobian-free Newton–Krylov (JFNK). The performance of the methods are evaluated over a range of energy group structures and core power levels. A novel physics-based approximation to a Jacobian-vector product has been developed to mitigate the impact of expensive on-line cross section processing steps. Numerical simulations demonstrating the efficiency of JFNKmore » and Anderson acceleration relative to standard Picard iteration are performed on a 3D model of a nuclear fuel assembly. Both criticality (k-eigenvalue) and critical boron search problems are considered.« less
A proximity algorithm accelerated by Gauss-Seidel iterations for L1/TV denoising models
NASA Astrophysics Data System (ADS)
Li, Qia; Micchelli, Charles A.; Shen, Lixin; Xu, Yuesheng
2012-09-01
Our goal in this paper is to improve the computational performance of the proximity algorithms for the L1/TV denoising model. This leads us to a new characterization of all solutions to the L1/TV model via fixed-point equations expressed in terms of the proximity operators. Based upon this observation we develop an algorithm for solving the model and establish its convergence. Furthermore, we demonstrate that the proposed algorithm can be accelerated through the use of the componentwise Gauss-Seidel iteration so that the CPU time consumed is significantly reduced. Numerical experiments using the proposed algorithm for impulsive noise removal are included, with a comparison to three recently developed algorithms. The numerical results show that while the proposed algorithm enjoys a high quality of the restored images, as the other three known algorithms do, it performs significantly better in terms of computational efficiency measured in the CPU time consumed.
NASA Astrophysics Data System (ADS)
Patel, Japan
Short mean free paths are characteristic of charged particles. High energy charged particles often have highly forward peaked scattering cross sections. Transport problems involving such charged particles are also highly optically thick. When problems simultaneously have forward peaked scattering and high optical thickness, their solution, using standard iterative methods, becomes very inefficient. In this dissertation, we explore Fokker-Planck-based acceleration for solving such problems.
A Radiation Transfer Solver for Athena Using Short Characteristics
NASA Astrophysics Data System (ADS)
Davis, Shane W.; Stone, James M.; Jiang, Yan-Fei
2012-03-01
We describe the implementation of a module for the Athena magnetohydrodynamics (MHD) code that solves the time-independent, multi-frequency radiative transfer (RT) equation on multidimensional Cartesian simulation domains, including scattering and non-local thermodynamic equilibrium (LTE) effects. The module is based on well known and well tested algorithms developed for modeling stellar atmospheres, including the method of short characteristics to solve the RT equation, accelerated Lambda iteration to handle scattering and non-LTE effects, and parallelization via domain decomposition. The module serves several purposes: it can be used to generate spectra and images, to compute a variable Eddington tensor (VET) for full radiation MHD simulations, and to calculate the heating and cooling source terms in the MHD equations in flows where radiation pressure is small compared with gas pressure. For the latter case, the module is combined with the standard MHD integrators using operator splitting: we describe this approach in detail, including a new constraint on the time step for stability due to radiation diffusion modes. Implementation of the VET method for radiation pressure dominated flows is described in a companion paper. We present results from a suite of test problems for both the RT solver itself and for dynamical problems that include radiative heating and cooling. These tests demonstrate that the radiative transfer solution is accurate and confirm that the operator split method is stable, convergent, and efficient for problems of interest. We demonstrate there is no need to adopt ad hoc assumptions of questionable accuracy to solve RT problems in concert with MHD: the computational cost for our general-purpose module for simple (e.g., LTE gray) problems can be comparable to or less than a single time step of Athena's MHD integrators, and only few times more expensive than that for more general (non-LTE) problems.
Jovian Chromophore Characteristics from Multispectral HST Images
NASA Technical Reports Server (NTRS)
Strycker, Paul D.; Chanover, Nancy J.; Simon-Miller, Amy A.; Banfield, Don; Gierasch, Peter J.
2011-01-01
The chromophores responsible for coloring the jovian atmosphere are embedded within Jupiter's vertical aerosol structure. Sunlight propagates through this vertical distribution of aerosol particles, whose colors are defined by omega-bar (sub 0)(lambda), and we remotely observe the culmination of the radiative transfer as I/F(lambda). In this study, we employed a radiative transfer code to retrieve omega-bar (sub 0)(lambda) for particles in Jupiter's tropospheric haze at seven wavelengths in the near-UV and visible regimes. The data consisted of images of the 2008 passage of Oval BA to the south of the Great Red Spot obtained by the Wide Field Planetary Camera 2 on-board the Hubble Space Telescope. We present derived particle colors for locations that were selected from 14 weather regions, which spanned a large range of observed colors. All omega-bar (sub 0)(lambda) curves were absorbing in the blue, and omega-bar (sub 0)(lambda) increased monotonically to approximately unity as wavelength increased. We found accurate fits to all omega-bar (sub 0)(lambda) curves using an empirically derived functional form: omega-bar (sub 0)(lambda) = 1 A exp(-B lambda). The best-fit parameters for the mean omega-bar (sub 0)(lambda) curve were A = 25.4 and B = 0.0149 for lambda in units of nm. We performed a principal component analysis (PCA) on our omega-bar (sub 0)(lambda) results and found that one or two independent chromophores were sufficient to produce the variations in omega-bar (sub 0)(lambda). A PCA of I/F(lambda) for the same jovian locations resulted in principal components (PCs) with roughly the same variances as the omega-bar (sub 0)(lambda) PCA, but they did not result in a one-to-one mapping of PC amplitudes between the omega-bar (sub 0)(lambda) PCA and I/F(lambda) PCA. We suggest that statistical analyses performed on I/ F(lambda) image cubes have limited applicability to the characterization of chromophores in the jovian atmosphere due to the sensitivity of 1/ F(lambda) to horizontal variations in the vertical aerosol distribution.
NASA Astrophysics Data System (ADS)
Marques, Carlos
A next generation Energy Recovery Linac (ERL) is under development in the Collider-Accelerator Department at Brookhaven National Laboratory (BNL). This ERL uses a superconducting radio frequency (SFR) cavity to produce an electric field gradient ideal to accelerate charged particles. As with many accelerators, higher-order modes (HOMs) can be induced by a beam of charged particles traversing the linear accelerator cavity. The excitation of these modes can result in problematic single and multi-bunch effects and also produce undesirable heat loads to the cryogenic system. Understanding HOM prevalence and structure inside the accelerator cavity is crucial for devising a procedure for extracting HOM power and promoting excellent beam quality. In this work, a method was created to identify and characterize HOMs using a perturbation technique on a copper (Cu) cavity prototype of the BNL3 linac and a double lambda/4 crab cavity. Both analyses and correlation between simulated and measured results are shown. A coaxial to dual-ridge waveguide HOM coupler was designed, constructed and implemented to extract power from HOMs simultaneously making an evanescent fundamental mode for the BNL3 cavity. A full description of the design is given along with a simulated analysis of its performance. Comparison between previous HOM coupler designs as well as correspondence between simulation and measurement is also given.
Overview of the negative ion based neutral beam injectors for ITER.
Schunke, B; Boilson, D; Chareyre, J; Choi, C-H; Decamps, H; El-Ouazzani, A; Geli, F; Graceffa, J; Hemsworth, R; Kushwah, M; Roux, K; Shah, D; Singh, M; Svensson, L; Urbani, M
2016-02-01
The ITER baseline foresees 2 Heating Neutral Beams (HNB's) based on 1 MeV 40 A D(-) negative ion accelerators, each capable of delivering 16.7 MW of deuterium atoms to the DT plasma, with an optional 3rd HNB injector foreseen as a possible upgrade. In addition, a dedicated diagnostic neutral beam will be injecting ≈22 A of H(0) at 100 keV as the probe beam for charge exchange recombination spectroscopy. The integration of the injectors into the ITER plant is nearly finished necessitating only refinements. A large number of components have passed the final design stage, manufacturing has started, and the essential test beds-for the prototype route chosen-will soon be ready to start.
Regularization iteration imaging algorithm for electrical capacitance tomography
NASA Astrophysics Data System (ADS)
Tong, Guowei; Liu, Shi; Chen, Hongyan; Wang, Xueyao
2018-03-01
The image reconstruction method plays a crucial role in real-world applications of the electrical capacitance tomography technique. In this study, a new cost function that simultaneously considers the sparsity and low-rank properties of the imaging targets is proposed to improve the quality of the reconstruction images, in which the image reconstruction task is converted into an optimization problem. Within the framework of the split Bregman algorithm, an iterative scheme that splits a complicated optimization problem into several simpler sub-tasks is developed to solve the proposed cost function efficiently, in which the fast-iterative shrinkage thresholding algorithm is introduced to accelerate the convergence. Numerical experiment results verify the effectiveness of the proposed algorithm in improving the reconstruction precision and robustness.
Li, Xia; Guo, Meifang; Su, Yongfu
2016-01-01
In this article, a new multidirectional monotone hybrid iteration algorithm for finding a solution to the split common fixed point problem is presented for two countable families of quasi-nonexpansive mappings in Banach spaces. Strong convergence theorems are proved. The application of the result is to consider the split common null point problem of maximal monotone operators in Banach spaces. Strong convergence theorems for finding a solution of the split common null point problem are derived. This iteration algorithm can accelerate the convergence speed of iterative sequence. The results of this paper improve and extend the recent results of Takahashi and Yao (Fixed Point Theory Appl 2015:87, 2015) and many others .
NASA Technical Reports Server (NTRS)
Desideri, J. A.; Steger, J. L.; Tannehill, J. C.
1978-01-01
The iterative convergence properties of an approximate-factorization implicit finite-difference algorithm are analyzed both theoretically and numerically. Modifications to the base algorithm were made to remove the inconsistency in the original implementation of artificial dissipation. In this way, the steady-state solution became independent of the time-step, and much larger time-steps can be used stably. To accelerate the iterative convergence, large time-steps and a cyclic sequence of time-steps were used. For a model transonic flow problem governed by the Euler equations, convergence was achieved with 10 times fewer time-steps using the modified differencing scheme. A particular form of instability due to variable coefficients is also analyzed.
Zwirtes, Ricardo; Narasimhan, Premkumar; Wind-Rotolo, Megan M; Xu, Dong; Hruska, Matthew W; Kishnani, Narendra; Colston, Elizabeth M; Srinivasan, Subasree
2016-11-01
The phase 2b EMERGE study compared the efficacy/safety of peginterferon lambda-1a (Lambda) and peginterferon alfa-2a (Alfa), both with ribavirin (RBV), for treatment of chronic hepatitis C virus (HCV) infection. A key safety finding was a higher frequency of hyperbilirubinemia with Lambda/RBV versus Alfa/RBV. To characterize mechanisms of hyperbilirubinemia associated with Lambda/RBV, we conducted a retrospective analysis of safety data from the HCV genotype 1 and genotype 4 cohort of the EMERGE study. Subjects were randomized to once-weekly Lambda (120/180/240 μg) or Alfa (180 μg), with daily RBV, for 48 weeks. Early-onset Lambda/RBV-related hyperbilirubinemia events (6-12 weeks) resulted mostly from RBV-induced hemolysis evidenced by sustained reticulocytosis and a predominantly unconjugated pattern of hyperbilirubinemia. The higher hyperbilirubinemia frequency with Lambda/RBV versus Alfa/RBV was attributed to bone marrow suppression known to occur with Alfa but not Lambda. Late-onset (>12 weeks) Lambda/RBV-related hyperbilirubinemia events occurred most frequently with higher Lambda doses and were associated with increased levels of hepatic transaminase and direct bilirubin fractions compared with early events. This dual pattern of hyperbilirubinemia observed while on Lambda/RBV treatment is thought to be caused by exaggerated RBV-induced hemolysis in early-onset events compared with possible direct Lambda-induced hepatocellular toxicity in late-onset events.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Stiernholm, N.B.J.; Verkoczy, L.K.; Berinstein, N.L.
1995-05-01
The constant region of the human Ig{lambda} locus consists of seven tandemly organized J-C gene segments. Although it has been established that the J-C{lambda}1, J-C{lambda}2, J-C{lambda}3, and J-C{lambda}7 gene segments are functional, and code for the four distinct Ig{lambda} isotypes found in human serum, the J-C{lambda}4, J-C{lambda}5, and J-C{lambda}6 gene segments are generally considered to be pseudogenes. Although one example of a functional J-C{lambda}6 gene segment has been documented, in the majority of cases, J-C{lambda}6 is rendered nonfunctional by virtue of a single duplication of four nucleotides, creating a premature translational arrest. We show here that rearrangements to the J-C{lambda}6more » gene segment do occur, and that such a rearrangement encodes an Ig{lambda} protein that lacks the terminal end of the constant region. We also show that this truncated protein is expressed on the surface with the IgH chain, creating an unusual surface Ig (sIg) receptor (sIg{triangle}CL). Cells that express this receptor on the surface do so at significantly reduced levels compared with clonally related variants, which express sIg receptors with conventional Ig{lambda} L chains. However, the effects of sIg cross-linking on tyrosine phosphorylation and surface expression of the CD25 and CD71 Ags are similar in cells that express conventional sIg receptors and in those that express sIg{triangle}CL receptors, suggesting that the latter could possibly function as an Ag receptor. 35 refs., 7 figs.« less
Existence and non-uniqueness of similarity solutions of a boundary-layer problem
NASA Technical Reports Server (NTRS)
Hussaini, M. Y.; Lakin, W. D.
1986-01-01
A Blasius boundary value problem with inhomogeneous lower boundary conditions f(0) = 0 and f'(0) = - lambda with lambda strictly positive was considered. The Crocco variable formulation of this problem has a key term which changes sign in the interval of interest. It is shown that solutions of the boundary value problem do not exist for values of lambda larger than a positive critical value lambda. The existence of solutions is proven for 0 lambda lambda by considering an equivalent initial value problem. It is found however that for 0 lambda lambda, solutions of the boundary value problem are nonunique. Physically, this nonuniqueness is related to multiple values of the skin friction.
Existence and non-uniqueness of similarity solutions of a boundary layer problem
NASA Technical Reports Server (NTRS)
Hussaini, M. Y.; Lakin, W. D.
1984-01-01
A Blasius boundary value problem with inhomogeneous lower boundary conditions f(0) = 0 and f'(0) = - lambda with lambda strictly positive was considered. The Crocco variable formulation of this problem has a key term which changes sign in the interval of interest. It is shown that solutions of the boundary value problem do not exist for values of lambda larger than a positive critical value lambda. The existence of solutions is proven for 0 lambda lambda by considering an equivalent initial value problem. It is found however that for 0 lambda lambda, solutions of the boundary value problem are nonunique. Physically, this nonuniqueness is related to multiple values of the skin friction.
Abulencia, A; Adelman, J; Affolder, T; Akimoto, T; Albrow, M G; Ambrose, D; Amerio, S; Amidei, D; Anastassov, A; Anikeev, K; Annovi, A; Antos, J; Aoki, M; Apollinari, G; Arguin, J-F; Arisawa, T; Artikov, A; Ashmanskas, W; Attal, A; Azfar, F; Azzi-Bacchetta, P; Azzurri, P; Bacchetta, N; Badgett, W; Barbaro-Galtieri, A; Barnes, V E; Barnett, B A; Baroiant, S; Bartsch, V; Bauer, G; Bedeschi, F; Behari, S; Belforte, S; Bellettini, G; Bellinger, J; Belloni, A; Benjamin, D; Beretvas, A; Beringer, J; Berry, T; Bhatti, A; Binkley, M; Bisello, D; Blair, R E; Blocker, C; Blumenfeld, B; Bocci, A; Bodek, A; Boisvert, V; Bolla, G; Bolshov, A; Bortoletto, D; Boudreau, J; Boveia, A; Brau, B; Brigliadori, L; Bromberg, C; Brubaker, E; Budagov, J; Budd, H S; Budd, S; Budroni, S; Burkett, K; Busetto, G; Bussey, P; Byrum, K L; Cabrera, S; Campanelli, M; Campbell, M; Canelli, F; Canepa, A; Carrillo, S; Carlsmith, D; Carosi, R; Carron, S; Casarsa, M; Castro, A; Catastini, P; Cauz, D; Cavalli-Sforza, M; Cerri, A; Cerrito, L; Chang, S H; Chen, Y C; Chertok, M; Chiarelli, G; Chlachidze, G; Chlebana, F; Cho, I; Cho, K; Chokheli, D; Chou, J P; Choudalakis, G; Chuang, S H; Chung, K; Chung, W H; Chung, Y S; Ciljak, M; Ciobanu, C I; Ciocci, M A; Clark, A; Clark, D; Coca, M; Compostella, G; Convery, M E; Conway, J; Cooper, B; Copic, K; Cordelli, M; Cortiana, G; Crescioli, F; Cuenca Almenar, C; Cuevas, J; Culbertson, R; Cully, J C; Cyr, D; DaRonco, S; D'Auria, S; Davies, T; D'Onofrio, M; Dagenhart, D; de Barbaro, P; De Cecco, S; Deisher, A; De Lentdecker, G; Dell'Orso, M; Delli Paoli, F; Demortier, L; Deng, J; Deninno, M; De Pedis, D; Derwent, P F; Di Giovanni, G P; Dionisi, C; Di Ruzza, B; Dittmann, J R; DiTuro, P; Dörr, C; Donati, S; Donega, M; Dong, P; Donini, J; Dorigo, T; Dube, S; Efron, J; Erbacher, R; Errede, D; Errede, S; Eusebi, R; Fang, H C; Farrington, S; Fedorko, I; Fedorko, W T; Feild, R G; Feindt, M; Fernandez, J P; Field, R; Flanagan, G; Foland, A; Forrester, S; Foster, G W; Franklin, M; Freeman, J C; Furic, I; Gallinaro, M; Galyardt, J; Garcia, J E; Garberson, F; Garfinkel, A F; Gay, C; Gerberich, H; Gerdes, D; Giagu, S; Giannetti, P; Gibson, A; Gibson, K; Gimmell, J L; Ginsburg, C; Giokaris, N; Giordani, M; Giromini, P; Giunta, M; Giurgiu, G; Glagolev, V; Glenzinski, D; Gold, M; Goldschmidt, N; Goldstein, J; Gomez, G; Gomez-Ceballos, G; Goncharov, M; González, O; Gorelov, I; Goshaw, A T; Goulianos, K; Gresele, A; Griffiths, M; Grinstein, S; Grosso-Pilcher, C; Group, R C; Grundler, U; Guimaraes da Costa, J; Gunay-Unalan, Z; Haber, C; Hahn, K; Hahn, S R; Halkiadakis, E; Hamilton, A; Han, B-Y; Han, J Y; Handler, R; Happacher, F; Hara, K; Hare, M; Harper, S; Harr, R F; Harris, R M; Hartz, M; Hatakeyama, K; Hauser, J; Heijboer, A; Heinemann, B; Heinrich, J; Henderson, C; Herndon, M; Heuser, J; Hidas, D; Hill, C S; Hirschbuehl, D; Hocker, A; Holloway, A; Hou, S; Houlden, M; Hsu, S-C; Huffman, B T; Hughes, R E; Husemann, U; Huston, J; Incandela, J; Introzzi, G; Iori, M; Ishizawa, Y; Ivanov, A; Iyutin, B; James, E; Jang, D; Jayatilaka, B; Jeans, D; Jensen, H; Jeon, E J; Jindariani, S; Jones, M; Joo, K K; Jun, S Y; Jung, J E; Junk, T R; Kamon, T; Karchin, P E; Kato, Y; Kemp, Y; Kephart, R; Kerzel, U; Khotilovich, V; Kilminster, B; Kim, D H; Kim, H S; Kim, J E; Kim, M J; Kim, S B; Kim, S H; Kim, Y K; Kimura, N; Kirsch, L; Klimenko, S; Klute, M; Knuteson, B; Ko, B R; Kondo, K; Kong, D J; Konigsberg, J; Korytov, A; Kotwal, A V; Kovalev, A; Kraan, A C; Kraus, J; Kravchenko, I; Kreps, M; Kroll, J; Krumnack, N; Kruse, M; Krutelyov, V; Kubo, T; Kuhlmann, S E; Kuhr, T; Kusakabe, Y; Kwang, S; Laasanen, A T; Labarga, L; Lai, S; Lami, S; Lammel, S; Lancaster, M; Lander, R L; Lannon, K; Lath, A; Latino, G; Lazzizzera, I; LeCompte, T; Lee, J; Lee, J; Lee, Y J; Lee, S W; Lefèvre, R; Leonardo, N; Leone, S; Levy, S; Lewis, J D; Lin, C; Lin, C S; Lindgren, M; Lipeles, E; Liss, T M; Lister, A; Litvintsev, D O; Liu, T; Lockyer, N S; Loginov, A; Loreti, M; Loverre, P; Lu, R-S; Lucchesi, D; Lujan, P; Lukens, P; Lungu, G; Lyons, L; Lys, J; Lysak, R; Lytken, E; Mack, P; MacQueen, D; Madrak, R; Maeshima, K; Makhoul, K; Maki, T; Maksimovic, P; Malde, S; Manca, G; Margaroli, F; Marginean, R; Marino, C; Marino, C P; Martin, A; Martin, M; Martin, V; Martínez, M; Maruyama, T; Mastrandrea, P; Masubuchi, T; Matsunaga, H; Mattson, M E; Mazini, R; Mazzanti, P; McFarland, K S; McIntyre, P; McNulty, R; Mehta, A; Mehtala, P; Menzemer, S; Menzione, A; Merkel, P; Mesropian, C; Messina, A; Miao, T; Miladinovic, N; Miles, J; Miller, R; Mills, C; Milnik, M; Mitra, A; Mitselmakher, G; Miyamoto, A; Moed, S; Moggi, N; Mohr, B; Moore, R; Morello, M; Movilla Fernandez, P; Mülmenstädt, J; Mukherjee, A; Muller, Th; Mumford, R; Murat, P; Nachtman, J; Nagano, A; Naganoma, J; Nahn, S; Nakano, I; Napier, A; Necula, V; Neu, C; Neubauer, M S; Nielsen, J; Nigmanov, T; Nodulman, L; Norniella, O; Nurse, E; Oh, S H; Oh, Y D; Oksuzian, I; Okusawa, T; Oldeman, R; Orava, R; Osterberg, K; Pagliarone, C; Palencia, E; Papadimitriou, V; Paramonov, A A; Parks, B; Pashapour, S; Patrick, J; Pauletta, G; Paulini, M; Paus, C; Pellett, D E; Penzo, A; Phillips, T J; Piacentino, G; Piedra, J; Pinera, L; Pitts, K; Plager, C; Pondrom, L; Portell, X; Poukhov, O; Pounder, N; Prokoshin, F; Pronko, A; Proudfoot, J; Ptochos, F; Punzi, G; Pursley, J; Rademacker, J; Rahaman, A; Ranjan, N; Rappoccio, S; Reisert, B; Rekovic, V; Renton, P; Rescigno, M; Richter, S; Rimondi, F; Ristori, L; Robson, A; Rodrigo, T; Rogers, E; Rolli, S; Roser, R; Rossi, M; Rossin, R; Ruiz, A; Russ, J; Rusu, V; Saarikko, H; Sabik, S; Safonov, A; Sakumoto, W K; Salamanna, G; Saltó, O; Saltzberg, D; Sánchez, C; Santi, L; Sarkar, S; Sartori, L; Sato, K; Savard, P; Savoy-Navarro, A; Scheidle, T; Schlabach, P; Schmidt, E E; Schmidt, M P; Schmitt, M; Schwarz, T; Scodellaro, L; Scott, A L; Scribano, A; Scuri, F; Sedov, A; Seidel, S; Seiya, Y; Semenov, A; Sexton-Kennedy, L; Sfyrla, A; Shapiro, M D; Shears, T; Shepard, P F; Sherman, D; Shimojima, M; Shochet, M; Shon, Y; Shreyber, I; Sidoti, A; Sinervo, P; Sisakyan, A; Sjolin, J; Slaughter, A J; Slaunwhite, J; Sliwa, K; Smith, J R; Snider, F D; Snihur, R; Soderberg, M; Soha, A; Somalwar, S; Sorin, V; Spalding, J; Spinella, F; Spreitzer, T; Squillacioti, P; Stanitzki, M; Staveris-Polykalas, A; St Denis, R; Stelzer, B; Stelzer-Chilton, O; Stentz, D; Strologas, J; Stuart, D; Suh, J S; Sukhanov, A; Sun, H; Suzuki, T; Taffard, A; Takashima, R; Takeuchi, Y; Takikawa, K; Tanaka, M; Tanaka, R; Tecchio, M; Teng, P K; Terashi, K; Tesarek, R J; Thom, J; Thompson, A S; Thomson, E; Tipton, P; Tiwari, V; Tkaczyk, S; Toback, D; Tokar, S; Tollefson, K; Tomura, T; Tonelli, D; Torre, S; Torretta, D; Tourneur, S; Trischuk, W; Tsuchiya, R; Tsuno, S; Turini, N; Ukegawa, F; Unverhau, T; Uozumi, S; Usynin, D; Vallecorsa, S; van Remortel, N; Varganov, A; Vataga, E; Vázquez, F; Velev, G; Veramendi, G; Veszpremi, V; Vidal, R; Vila, I; Vilar, R; Vine, T; Vollrath, I; Volobouev, I; Volpi, G; Würthwein, F; Wagner, P; Wagner, R G; Wagner, R L; Wagner, J; Wagner, W; Wallny, R; Wang, S M; Warburton, A; Waschke, S; Waters, D; Weinberger, M; Wester, W C; Whitehouse, B; Whiteson, D; Wicklund, A B; Wicklund, E; Williams, G; Williams, H H; Wilson, P; Winer, B L; Wittich, P; Wolbers, S; Wolfe, C; Wright, T; Wu, X; Wynne, S M; Yagil, A; Yamamoto, K; Yamaoka, J; Yamashita, T; Yang, C; Yang, U K; Yang, Y C; Yao, W M; Yeh, G P; Yoh, J; Yorita, K; Yoshida, T; Yu, G B; Yu, I; Yu, S S; Yun, J C; Zanello, L; Zanetti, A; Zaw, I; Zhang, X; Zhou, J; Zucchelli, S
2007-03-23
We report a measurement of the Lambda b0 lifetime in the exclusive decay Lambda b0-->J/psi Lambda 0 in pp collisions at square root s=1.96 TeV using an integrated luminosity of 1.0 fb-1 of data collected by the CDF II detector at the Fermilab Tevatron. Using fully reconstructed decays, we measure tau(Lambda b0)=1.593(-0.078)(+0.083)(stat)+/-0.033(syst) ps. This is the single most precise measurement of tau(Lambda b0) and is 3.2sigma higher than the current world average.
Observation of the baryonic B decay B{sup 0}{yields}{Lambda}{sub c}{sup +}{Lambda}K{sup -}
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lees, J. P.; Poireau, V.; Tisserand, V.
2011-10-01
We report the observation of the baryonic B decay B{sup 0}{yields}{Lambda}{sub c}{sup +}{Lambda}K{sup -} with a significance larger than 7 standard deviations based on 471x10{sup 6} BB pairs collected with the BABAR detector at the PEP-II storage ring at SLAC. We measure the branching fraction for the decay B{sup 0}{yields}{Lambda}{sub c}{sup +}{Lambda}K{sup -} to be (3.8{+-}0.8{sub stat}{+-}0.2{sub sys}{+-}1.0{sub {Lambda}}{sub c}{sup +})x10{sup -5}. The uncertainties are statistical, systematic, and due to the uncertainty in the {Lambda}{sub c}{sup +} branching fraction. We find that the {Lambda}{sub c}{sup +}K{sup -} invariant-mass distribution shows an enhancement above 3.5 GeV/c{sup 2}.
Realistic NLTE Radiative Transfer for Modeling Stellar Winds
NASA Technical Reports Server (NTRS)
Bennett, Philip D.
1999-01-01
This NASA grant supported the development of codes to solve the non-LTE multi-level spherical radiative transfer problem in the presence of velocity fields. Much of this work was done in collaboration with Graham Harper (CASA, University of Colorado). These codes were developed for application to the cool, low-velocity winds of evolved late-type stars. Particular emphasis was placed on modeling the wind of lambda Velorum (K4 lb), the brightest K supergiant in the sky, based on extensive observations of the ultraviolet spectrum with the HST/GHRS from GO program 5307. Several solution techniques were examined, including the Eddington factor Approach described in detail by Bennett & Harper (1997). An Eddington factor variant of Harper's S-MULTI code (Harper 1994) for stationary atmospheres was developed and implemented, although full convergence was not realized. The ratio of wind terminal velocity to turbulent velocity is large (approx. 0.3-0.5) in these cool star winds so this assumption of stationarity provides reasonable starting models. Final models, incorporating specified wind laws, were converged using the comoving CRD S-MULTI code. Details of the solution procedure were published by Bennett & Harper (1997). Our analysis of the wind of lambda Vel, based on wind absorption superimposed on chromospheric emission lines in the ultraviolet, can be found in Carpenter et al. (1999). In this paper, we compare observed wind absorption features to an exact CRD calculation in the comoving frame, and also to a much quicker, but approximate, method using the SEI (Sobolev with Exact Integration) code of Lamers, Cerruti-Sola, & Perinotto (1987). Carpenter et al. (1999) provide detailed comparisons of the exact CRD and approximate SEI results and discuss when SEI is adequate to use for computing wind line profiles. Unfortunately, the observational material is insufficient to unambiguously determine the wind acceleration law for lambda Vel. Relatively few unblended Fe II lines of optical depth sensitive to the wind acceleration region are present in the existing HST/GHRS data set. Most of the Fe II lines are either too optically thick (resulting in a board, black wind absorption profile) or too optically thin (resulting in no wind absorption feature present). Also, most of the ultraviolet spectra obtained from HST GO-5307 was at medium resolution (R approx. 40,000, corresponding to a velocity resolution of 7.5 km/s). This is simply inadequate to resolve the turbulence in the outer wind; a key parameter in theoretical wind models. We can now say that an unambiguous determination of the wind velocity law in lambda Vel will require complete coverage of the ultraviolet spectrum at high dispersion (R approx. 10(exp 5), or 3 km/s). This is now feasible usin, the STIS echelle spectrograph on-board HST.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Umeya, Atsushi; Harada, Toru; Research Center for Physics and Mathematics, Osaka Electro-Communication University, Neyagawa, Osaka 572-8530
2011-03-15
We theoretically investigate energy spacings of doublets in {sub {Lambda}L}i hypernuclear isotopes with A=7-10 in shell-model calculations with a {Lambda}N-{Sigma}N coupling effect. The calculated results show that the energy shifts are {Delta}{epsilon}=0.09-0.28 MeV and the {Sigma}-mixing probabilities are P{sub {Sigma}}=0.10%-0.34% in {Lambda} ground states for the isotopes because of the {Lambda}N-{Sigma}N coupling in the first-order perturbation. It is found that the energy spacing of the doublet is enhanced as a neutron number N increases; the contribution of the {Lambda}N-{Sigma}N coupling interaction is comparable to that of the {Lambda}N interaction in the neutron-rich {Lambda} hypernuclei. The coherent mechanism of this doublet-spacingmore » enhancement is also discussed in terms of Fermi-type and Gamow-Teller-type {Lambda}N-{Sigma}N couplings.« less
Parallel/Vector Integration Methods for Dynamical Astronomy
NASA Astrophysics Data System (ADS)
Fukushima, Toshio
1999-01-01
This paper reviews three recent works on the numerical methods to integrate ordinary differential equations (ODE), which are specially designed for parallel, vector, and/or multi-processor-unit(PU) computers. The first is the Picard-Chebyshev method (Fukushima, 1997a). It obtains a global solution of ODE in the form of Chebyshev polynomial of large (> 1000) degree by applying the Picard iteration repeatedly. The iteration converges for smooth problems and/or perturbed dynamics. The method runs around 100-1000 times faster in the vector mode than in the scalar mode of a certain computer with vector processors (Fukushima, 1997b). The second is a parallelization of a symplectic integrator (Saha et al., 1997). It regards the implicit midpoint rules covering thousands of timesteps as large-scale nonlinear equations and solves them by the fixed-point iteration. The method is applicable to Hamiltonian systems and is expected to lead an acceleration factor of around 50 in parallel computers with more than 1000 PUs. The last is a parallelization of the extrapolation method (Ito and Fukushima, 1997). It performs trial integrations in parallel. Also the trial integrations are further accelerated by balancing computational load among PUs by the technique of folding. The method is all-purpose and achieves an acceleration factor of around 3.5 by using several PUs. Finally, we give a perspective on the parallelization of some implicit integrators which require multiple corrections in solving implicit formulas like the implicit Hermitian integrators (Makino and Aarseth, 1992), (Hut et al., 1995) or the implicit symmetric multistep methods (Fukushima, 1998), (Fukushima, 1999).
GPU-accelerated iterative reconstruction for limited-data tomography in CBCT systems.
de Molina, Claudia; Serrano, Estefania; Garcia-Blas, Javier; Carretero, Jesus; Desco, Manuel; Abella, Monica
2018-05-15
Standard cone-beam computed tomography (CBCT) involves the acquisition of at least 360 projections rotating through 360 degrees. Nevertheless, there are cases in which only a few projections can be taken in a limited angular span, such as during surgery, where rotation of the source-detector pair is limited to less than 180 degrees. Reconstruction of limited data with the conventional method proposed by Feldkamp, Davis and Kress (FDK) results in severe artifacts. Iterative methods may compensate for the lack of data by including additional prior information, although they imply a high computational burden and memory consumption. We present an accelerated implementation of an iterative method for CBCT following the Split Bregman formulation, which reduces computational time through GPU-accelerated kernels. The implementation enables the reconstruction of large volumes (>1024 3 pixels) using partitioning strategies in forward- and back-projection operations. We evaluated the algorithm on small-animal data for different scenarios with different numbers of projections, angular span, and projection size. Reconstruction time varied linearly with the number of projections and quadratically with projection size but remained almost unchanged with angular span. Forward- and back-projection operations represent 60% of the total computational burden. Efficient implementation using parallel processing and large-memory management strategies together with GPU kernels enables the use of advanced reconstruction approaches which are needed in limited-data scenarios. Our GPU implementation showed a significant time reduction (up to 48 ×) compared to a CPU-only implementation, resulting in a total reconstruction time from several hours to few minutes.
The role of template superhelicity in the initiation of bacteriophage lambda DNA replication.
Alfano, C; McMacken, R
1988-01-01
The prepriming steps in the initiation of bacteriophage lambda DNA replication depend on the action of the lambda O and P proteins and on the DnaB helicase, single-stranded DNA binding protein (SSB), and DnaJ and DnaK heat shock proteins of the E. coli host. The binding of multiple copies of the lambda O protein to the phage replication origin (ori lambda) initiates the ordered assembly of a series of nucleoprotein structures that form at ori lambda prior to DNA unwinding, priming and DNA synthesis steps. Since the initiation of lambda DNA replication is known to occur only on supercoiled templates in vivo and in vitro, we examined how the early steps in lambda DNA replication are influenced by superhelical tension. All initiation complexes formed prior to helicase-mediated DNA-unwinding form with high efficiency on relaxed ori lambda DNA. Nonetheless, the DNA templates in these structures must be negatively supertwisted before they can be replicated. Once DNA helicase unwinding is initiated at ori lambda, however, later steps in lambda DNA replication proceed efficiently in the absence of superhelical tension. We conclude that supercoiling is required during the initiation of lambda DNA replication to facilitate entry of a DNA helicase, presumably the DnaB protein, between the DNA strands. Images PMID:2847118
Coarse mesh and one-cell block inversion based diffusion synthetic acceleration
NASA Astrophysics Data System (ADS)
Kim, Kang-Seog
DSA (Diffusion Synthetic Acceleration) has been developed to accelerate the SN transport iteration. We have developed solution techniques for the diffusion equations of FLBLD (Fully Lumped Bilinear Discontinuous), SCB (Simple Comer Balance) and UCB (Upstream Corner Balance) modified 4-step DSA in x-y geometry. Our first multi-level method includes a block Gauss-Seidel iteration for the discontinuous diffusion equation, uses the continuous diffusion equation derived from the asymptotic analysis, and avoids void cell calculation. We implemented this multi-level procedure and performed model problem calculations. The results showed that the FLBLD, SCB and UCB modified 4-step DSA schemes with this multi-level technique are unconditionally stable and rapidly convergent. We suggested a simplified multi-level technique for FLBLD, SCB and UCB modified 4-step DSA. This new procedure does not include iterations on the diffusion calculation or the residual calculation. Fourier analysis results showed that this new procedure was as rapidly convergent as conventional modified 4-step DSA. We developed new DSA procedures coupled with 1-CI (Cell Block Inversion) transport which can be easily parallelized. We showed that 1-CI based DSA schemes preceded by SI (Source Iteration) are efficient and rapidly convergent for LD (Linear Discontinuous) and LLD (Lumped Linear Discontinuous) in slab geometry and for BLD (Bilinear Discontinuous) and FLBLD in x-y geometry. For 1-CI based DSA without SI in slab geometry, the results showed that this procedure is very efficient and effective for all cases. We also showed that 1-CI based DSA in x-y geometry was not effective for thin mesh spacings, but is effective and rapidly convergent for intermediate and thick mesh spacings. We demonstrated that the diffusion equation discretized on a coarse mesh could be employed to accelerate the transport equation. Our results showed that coarse mesh DSA is unconditionally stable and is as rapidly convergent as fine mesh DSA in slab geometry. For x-y geometry our coarse mesh DSA is very effective for thin and intermediate mesh spacings independent of the scattering ratio, but is not effective for purely scattering problems and high aspect ratio zoning. However, if the scattering ratio is less than about 0.95, this procedure is very effective for all mesh spacing.
NASA Technical Reports Server (NTRS)
Martel, Hugo
1994-01-01
We study the effect of the cosmological constant Lambda on galaxy formation using a simple spherical top-hat overdensity model. We consider models with Omega(sub 0) = 0.2, lambda(sub 0) = 0, and Omega(sub 0) = 0.2, lambda(sub 0) = 0.8 (where Omega(sub 0) is the density parameter, and lambda(sub 0) identically equal Lambda/3 H(sub 0 exp 2) where H(sub 0) is the Hubble constant). We adjust the initial power spectrum amplitude so that both models reproduce the same large-scale structures. The galaxy formation era in the lambda(sub 0) = 0 model occurs early (z approximately 6) and is very short, whereas in the lambda(sub 0) = 0.8 model the galaxy formation era starts later (z approximately 4), and last much longer, possibly all the way to the present. Consequently, galaxies at low redshift (z less than 1) are significantly more evolved in the lambda(sub 0) = 0 model than in the lambda(sub 0) = 0.8 model. This result implies that previous attempts to determine Lambda using the number counts versus redshift test are probably unreliable.
Iterative algorithms for computing the feedback Nash equilibrium point for positive systems
NASA Astrophysics Data System (ADS)
Ivanov, I.; Imsland, Lars; Bogdanova, B.
2017-03-01
The paper studies N-player linear quadratic differential games on an infinite time horizon with deterministic feedback information structure. It introduces two iterative methods (the Newton method as well as its accelerated modification) in order to compute the stabilising solution of a set of generalised algebraic Riccati equations. The latter is related to the Nash equilibrium point of the considered game model. Moreover, we derive the sufficient conditions for convergence of the proposed methods. Finally, we discuss two numerical examples so as to illustrate the performance of both of the algorithms.
Techniques for Accelerating Iterative Methods for the Solution of Mathematical Problems
1989-07-01
m, we can find a solu ion to the problem by using generalized inverses. Hence, ;= Ih.i = GAi = G - where G is of the form (18). A simple choice for V...have understood why I was not available for many of their activities and not home many of the nights. Their love is forever. I have saved the best for...Xk) Extrapolation applied to terms xP through Xk F Operator on x G Iteration function Ik Identity matrix of rank k Solution of the problem or the limit
A Hardware-Accelerated Quantum Monte Carlo framework (HAQMC) for N-body systems
NASA Astrophysics Data System (ADS)
Gothandaraman, Akila; Peterson, Gregory D.; Warren, G. Lee; Hinde, Robert J.; Harrison, Robert J.
2009-12-01
Interest in the study of structural and energetic properties of highly quantum clusters, such as inert gas clusters has motivated the development of a hardware-accelerated framework for Quantum Monte Carlo simulations. In the Quantum Monte Carlo method, the properties of a system of atoms, such as the ground-state energies, are averaged over a number of iterations. Our framework is aimed at accelerating the computations in each iteration of the QMC application by offloading the calculation of properties, namely energy and trial wave function, onto reconfigurable hardware. This gives a user the capability to run simulations for a large number of iterations, thereby reducing the statistical uncertainty in the properties, and for larger clusters. This framework is designed to run on the Cray XD1 high performance reconfigurable computing platform, which exploits the coarse-grained parallelism of the processor along with the fine-grained parallelism of the reconfigurable computing devices available in the form of field-programmable gate arrays. In this paper, we illustrate the functioning of the framework, which can be used to calculate the energies for a model cluster of helium atoms. In addition, we present the capabilities of the framework that allow the user to vary the chemical identities of the simulated atoms. Program summaryProgram title: Hardware Accelerated Quantum Monte Carlo (HAQMC) Catalogue identifier: AEEP_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEEP_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 691 537 No. of bytes in distributed program, including test data, etc.: 5 031 226 Distribution format: tar.gz Programming language: C/C++ for the QMC application, VHDL and Xilinx 8.1 ISE/EDK tools for FPGA design and development Computer: Cray XD1 consisting of a dual-core, dualprocessor AMD Opteron 2.2 GHz with a Xilinx Virtex-4 (V4LX160) or Xilinx Virtex-II Pro (XC2VP50) FPGA per node. We use the compute node with the Xilinx Virtex-4 FPGA Operating system: Red Hat Enterprise Linux OS Has the code been vectorised or parallelized?: Yes Classification: 6.1 Nature of problem: Quantum Monte Carlo is a practical method to solve the Schrödinger equation for large many-body systems and obtain the ground-state properties of such systems. This method involves the sampling of a number of configurations of atoms and averaging the properties of the configurations over a number of iterations. We are interested in applying the QMC method to obtain the energy and other properties of highly quantum clusters, such as inert gas clusters. Solution method: The proposed framework provides a combined hardware-software approach, in which the QMC simulation is performed on the host processor, with the computationally intensive functions such as energy and trial wave function computations mapped onto the field-programmable gate array (FPGA) logic device attached as a co-processor to the host processor. We perform the QMC simulation for a number of iterations as in the case of our original software QMC approach, to reduce the statistical uncertainty of the results. However, our proposed HAQMC framework accelerates each iteration of the simulation, by significantly reducing the time taken to calculate the ground-state properties of the configurations of atoms, thereby accelerating the overall QMC simulation. We provide a generic interpolation framework that can be extended to study a variety of pure and doped atomic clusters, irrespective of the chemical identities of the atoms. For the FPGA implementation of the properties, we use a two-region approach for accurately computing the properties over the entire domain, employ deep pipelines and fixed-point for all our calculations guaranteeing the accuracy required for our simulation.
Physics and engineering design of the accelerator and electron dump for SPIDER
NASA Astrophysics Data System (ADS)
Agostinetti, P.; Antoni, V.; Cavenago, M.; Chitarin, G.; Marconato, N.; Marcuzzi, D.; Pilan, N.; Serianni, G.; Sonato, P.; Veltri, P.; Zaccaria, P.
2011-06-01
The ITER Neutral Beam Test Facility (PRIMA) is planned to be built at Consorzio RFX (Padova, Italy). PRIMA includes two experimental devices: a full size ion source with low voltage extraction called SPIDER and a full size neutral beam injector at full beam power called MITICA. SPIDER is the first experimental device to be built and operated, aiming at testing the extraction of a negative ion beam (made of H- and in a later stage D- ions) from an ITER size ion source. The main requirements of this experiment are a H-/D- extracted current density larger than 355/285 A m-2, an energy of 100 keV and a pulse duration of up to 3600 s. Several analytical and numerical codes have been used for the design optimization process, some of which are commercial codes, while some others were developed ad hoc. The codes are used to simulate the electrical fields (SLACCAD, BYPO, OPERA), the magnetic fields (OPERA, ANSYS, COMSOL, PERMAG), the beam aiming (OPERA, IRES), the pressure inside the accelerator (CONDUCT, STRIP), the stripping reactions and transmitted/dumped power (EAMCC), the operating temperature, stress and deformations (ALIGN, ANSYS) and the heat loads on the electron dump (ED) (EDAC, BACKSCAT). An integrated approach, taking into consideration at the same time physics and engineering aspects, has been adopted all along the design process. Particular care has been taken in investigating the many interactions between physics and engineering aspects of the experiment. According to the 'robust design' philosophy, a comprehensive set of sensitivity analyses was performed, in order to investigate the influence of the design choices on the most relevant operating parameters. The design of the SPIDER accelerator, here described, has been developed in order to satisfy with reasonable margin all the requirements given by ITER, from the physics and engineering points of view. In particular, a new approach to the compensation of unwanted beam deflections inside the accelerator and a new concept for the ED have been introduced.
Development of in-vitro models to elucidate mechanisms of intrinsic cellular and tissue fluorescence
NASA Astrophysics Data System (ADS)
Savage, Howard E.; Kolli, Venkateswara; Saha, Sanjoy; Zhang, Jian C.; Glasgold, Mark; Sacks, Peter G.; Alfano, Robert R.; Schantz, Stimson P.
1995-04-01
In vitro cell model systems have been used to study the mechanisms of intrinsic cellular and tissue fluorescence as a potential biomarker for cancer. Phenotypic characteristics of cancer that are different from normal tissue include changes in histoarchitecture, proliferation rates and differentiation. a nitrosmethlybenzylamine (NMBA)/rat esophageal carcinogenesis model (NMBA), a transforming growth factor beta (TGF- (beta) )/normal epithelial cell model, and a retinoic acid (RA)/multicellular tumor spheroid model (RAMTS) were used to assess fluorescence changes associated respectively with changes in histoarchitecture, proliferation rates and differentiation. A xenon based fluorescence spectrophotometer (Mediscience Corp.) was used to collect excitation and emission spectra. Two excitation scans ((lambda) Ex 200-360 nm, (lambda) Em 380 nm; (lambda) Ex 240-430 nm, (lambda) Em 450 nm) and two emission scans ((lambda) Ex 300 nm, (lambda) Em 320-580 nm; (lambda) Ex 340 nm, (lambda) Em 360-660 nm) were used to analyze the three model systems. Using the NMBA model. Differences were seen in the excitation scan ((lambda) Ex 200-360 nm, (lambda) Em 380 nm) and the emission scan ((lambda) Ex 340 nm, (lambda) Em 360-660 nm) when normal rat esophageal tissue was compared to hyperplastic and tumor tissue. In the (TGF-(beta) ) model, differences were seen in the excitation scan ((lambda) Ex 240-430 nm, (lambda) Em 450 nm) when comparing proliferation slowed (TGF-(beta) treated) epithelial cells to their untreated controls. In the RAMTS model, differences were seen with all four scans when RA treated multicellular tumor spheroids (nondifferentiating) were compared to untreated control cells (differentiating). The data indicate that fluorescence changes seen in these model systems may relate to changes in histoarchitecture, proliferation rates and differentiation. Their relationship to in vivo fluorescence changes seen in cancer patients remains to be elucidated.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Aaltonen, T.; Maki, T.; Mehtala, P.
2009-02-01
This article presents the first measurement of the ratio of branching fractions B({lambda}{sub b}{sup 0}{yields}{lambda}{sub c}{sup +}{mu}{sup -}{nu}{sub {mu}})/B({lambda}{sub b}{sup 0}{yields}{lambda}{sub c}{sup +}{pi}{sup -}). Measurements in two control samples using the same technique B(B{sup 0}{yields}D{sup +}{mu}{sup -}{nu}{sub {mu}})/B(B{sup 0}{yields}D{sup +}{pi}{sup -}) and B(B{sup 0}{yields}D*(2010){sup +}{mu}{sup -}{nu}{sub {mu}})/B(B{sup 0}{yields}D*(2010){sup +}{pi}{sup -}) are also reported. The analysis uses data from an integrated luminosity of approximately 172 pb{sup -1} of pp collisions at {radical}(s)=1.96 TeV, collected with the CDF II detector at the Fermilab Tevatron. The relative branching fractions are measured to be (B({lambda}{sub b}{sup 0}{yields}{lambda}{sub c}{sup +}{mu}{sup -}{nu}{sub {mu}})/B({lambda}{sub b}{sup 0}{yields}{lambda}{sub c}{supmore » +}{pi}{sup -}))=16.6{+-}3.0(stat){+-}1.0(syst)(+2.6/-3.4)(PDG){+-}0.3 (EBR), (B(B{sup 0}{yields}D{sup +}{mu}{sup -}{nu}{sub {mu}})/B(B{sup 0}{yields}D{sup +}{pi}{sup -}))9.9{+-}1.0(stat){+-}0.6(syst){+-}0.4(PDG){+-}0.5(EBR), and (B(B{sup 0}{yields}D*(2010){sup +}{mu}{sup -}{nu}{sub {mu}})/B(B{sup 0}{yields}D*(2010){sup +}{pi}{sup -}))=16.5{+-}2.3(stat){+-} 0.6(syst){+-}0.5(PDG){+-}0.8(EBR). The uncertainties are from statistics (stat), internal systematics (syst), world averages of measurements published by the Particle Data Group or subsidiary measurements in this analysis (PDG), and unmeasured branching fractions estimated from theory (EBR), respectively. This article also presents measurements of the branching fractions of four new {lambda}{sub b}{sup 0} semileptonic decays: {lambda}{sub b}{sup 0}{yields}{lambda}{sub c}(2595){sup +}{mu}{sup -}{nu}{sub {mu}}, {lambda}{sub b}{sup 0}{yields}{lambda}{sub c}(2625){sup +}{mu}{sup -}{nu}{sub {mu}}, {lambda}{sub b}{sup 0}{yields}{sigma}{sub c}(2455){sup 0}{pi}{sup +}{mu}{sup -}{nu}{sub {mu}}, and {lambda}{sub b}{sup 0}{yields}{sigma}{sub c}(2455){sup ++}{pi}{sup -}{mu}{sup -}{nu}{sub {mu}}, relative to the branching fraction of the {lambda}{sub b}{sup 0}{yields}{lambda}{sub c}{sup +}{mu}{sup -}{nu}{sub {mu}} decay. Finally, the transverse-momentum distribution of {lambda}{sub b}{sup 0} baryons produced in pp collisions is measured and found to be significantly different from that of B{sup 0} mesons, which results in a modification in the production cross-section ratio {sigma}{sub {lambda}{sub b}{sup 0}}/{sigma}{sub B{sup 0}} with respect to the CDF I measurement.« less
Movement of the Melt Metal Layer under Conditions Typical of Transient Events in ITER
NASA Astrophysics Data System (ADS)
Poznyak, I. M.; Safronov, V. M.; Zybenko, V. Yu.
2017-12-01
During the operation of ITER, protective coatings of the divertor and the first wall will be exposed to significant plasma heat loads which may cause a huge erosion. One of the major failure mechanisms of metallic armor is diminution of their thickness due to the melt layer displacement. New experimental data are required in order to develop and validate physical models of the melt layer movement. The paper presents the experiments where metal targets were irradiated by a plasma stream at the quasi-stationary high-current plasma accelerator QSPA-T. The obtained data allow one to determine the velocity and acceleration of the melt layer at various distances from the plasma stream axis. The force causing the radial movement of the melt layer is shown to create an acceleration whose order of magnitude is 1000g. The pressure gradient is not responsible for creating this large acceleration. To investigate the melt layer movement under a known force, the experiment with a rotating target was carried out. The influence of centrifugal and Coriolis forces led to appearance of curved elongated waves on the surface. The surface profile changed: there is no hill in the central part of the erosion crater in contrast to the stationary target. The experimental data clarify the trends in the melt motion that are required for development of theoretical models.
On the nature of the nova-like variable CD-42 deg 14462
NASA Technical Reports Server (NTRS)
Guinan, E. F.; Sion, E. M.
1981-01-01
Low dispersion long and short wavelength IUE spectra of the nova like system CD-42 deg 14462 were obtained on August 24 U.T. The short wave spectrum exhibits absorption features due to C III (lambda 1175), Lalpha 1216), NV (lambda1240), HeII (lambda 1640), SiIV (lambda1394), NIV (lambda1875) with CIV (lambda1550) as a P Cygni feature with blue shifted absorption suggesting the presence of material leaving the system. Possible interpretations of this object are discussed.
Anti p and anti Lambda production in Si + Au collisions at the AGS
NASA Technical Reports Server (NTRS)
Wu, Yue-Dong
1996-01-01
(anti (ital p)) and (anti (Lambda)) production in central Si + Au collisions has been measured by E589 at the BNL-AGS. Preliminary (ital m)(sub (perpendicular)) spectra are presented for (anti (ital p))'s and (anti (Lambda))'s. The (ital dn/dy) distribution for (anti (ital p))'s is also presented. Based on the (anti (ital p)) and (anti (Lambda)) measurements, (anti (Lambda))/(anti (ital p)) ratios are calculated in the rapidity range of 1.1-1.5.
The Problem of Inertia in a Friedmann Universe
NASA Technical Reports Server (NTRS)
Kazanas, Demosthenes
2012-01-01
In this talk I will discuss the origin of inertia in a curved spacetime, particularly the spatially flat, open and closed Friedmann universes. This is done using Sciama's law of inertial induction, which is based on Mach's principle, and expresses the analogy between the retarded far fields of electrodynamics and those of gravitation. After obtaining covariant expressions for electromagnetic fields due to an accelerating point charge in Friedmann models, we adopt Sciama's law to obtain the inertial force on an accelerating mass $m$ by integrating over the contributions from all the matter in the universe. The resulting inertial force has the form $F = -kma$ where the constant $k < 1 $ depends on the choice of the cosmological parameters such as $\\Omega_{M},\\ \\Omega_{\\Lambda}, $ and $\\Omega_{R}$. The values of $k$ obtained suggest that inertial contribution from dark matter can be the source for the missing part of the inertial force.
Is cosmic acceleration slowing down?
DOE Office of Scientific and Technical Information (OSTI.GOV)
Shafieloo, Arman; Sahni, Varun; Starobinsky, Alexei A.
2009-11-15
We investigate the course of cosmic expansion in its recent past using the Constitution SN Ia sample, along with baryon acoustic oscillations (BAO) and cosmic microwave background (CMB) data. Allowing the equation of state of dark energy (DE) to vary, we find that a coasting model of the universe (q{sub 0}=0) fits the data about as well as Lambda cold dark matter. This effect, which is most clearly seen using the recently introduced Om diagnostic, corresponds to an increase of Om and q at redshifts z < or approx. 0.3. This suggests that cosmic acceleration may have already peaked andmore » that we are currently witnessing its slowing down. The case for evolving DE strengthens if a subsample of the Constitution set consisting of SNLS+ESSENCE+CfA SN Ia data is analyzed in combination with BAO+CMB data. The effect we observe could correspond to DE decaying into dark matter (or something else)« less
NASA Astrophysics Data System (ADS)
Palmieri, Vincenzo; Rossi, Antonio Alessandro; Stark, Sergey Yu; Vaglio, Ruggero
2014-08-01
The majority of the literature on superconducting cavities for particle accelerators concentrates on the interaction of a radiofrequency (RF) electromagnetic field with a superconductor cooled in liquid helium, generally either at a fixed temperature of 4.2 K or 1.8 K, basing the analysis of experimental results on the assumption that the superconductor is at the same temperature as the infinite reservoir of liquid helium. Only a limited number of papers have extended their analysis to the more complex overall system composed of an RF field, a superconductor and liquid helium. Only a few papers have analyzed, for example, the problem of the Kapitza resistance, i.e. the thermal boundary resistance between the superconductor and the superfluid helium. Among them, the general conclusion is that the Kapitza resistance, one of the most controversial and less understood topics in physics, is generally negligible, or not relevant for the performance enhancement of cavities. In our work presented here, studying the performance of 6 GHz niobium (Nb) test cavities, we have discovered and studied a new effect consisting of an abrupt change in the surface resistance versus temperature at the superfluid helium lambda transition Tλ. This abrupt change (or ‘jump’) clearly appears when the RF measurement of a cavity is performed at constant power rather than at a constant field. We have correlated this jump to a change in the thermal exchange regime across the lambda transition, and, through a simple thermal model and further reasonable assumptions, we have calculated the thermal boundary resistance between niobium and liquid helium in the temperature range between 4.2 K and 1.8 K. We find that the absolute values of the thermal resistance both above and below the lambda point are fully compatible with the data reported in the literature for heat transfer to pool boiling helium I (HeI) above Tλ and for the Kapitza interface resistance (below Tλ) between a polished metal surface and superfluid HeII. Finally, based on the well-documented evidence that the surface status of metal to liquid helium influences the heat exchange towards the fluid, and specifically the Kapitza resistance below Tλ, we have tested an anodization process external to the cavity, comparing the performances of the cavity before and after external anodization. The tests were done without breaking the vacuum inside the cavity or modifying the inner superconducting layer in any way, and were repeated on different samples. The results show that when the cavity is externally anodized, both the Q-factor and the maximum accelerating field increase. Again, when the oxide layer is removed, the Q-factor shifts towards a lower level and the maximum accelerating field is also reduced.
ASYMMETRIC ABSORPTION PROFILES OF Ly{alpha} AND Ly{beta} IN DAMPED Ly{alpha} SYSTEMS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lee, Hee-Won, E-mail: hwlee@sejong.ac.kr
2013-08-01
Damped Ly{alpha} systems observed in the quasar spectra are characterized by a high neutral hydrogen column density, N{sub HI} > 2 x 10{sup 20} cm{sup -2}. The absorption wing profiles are often fitted using the Voigt function due to the fact that the scattering cross section near the resonant line center is approximately described by the Lorentzian function. Since a hydrogen atom has infinitely many p states that participate in the electric dipole interaction, the cross section starts to deviate from the Lorentzian in an asymmetric way in the line wing regions. We investigate this asymmetry in the absorption linemore » profiles around Ly{alpha} and Ly{beta} as a function of the neutral hydrogen column density N{sub HI}. In terms of {Delta}{lambda} {identical_to} {lambda} - {lambda}{sub {alpha}}, we expand the Kramers-Heisenberg formula around Ly{alpha} to find {sigma}({lambda}) {approx_equal} (0.5f{sub 12}){sup 2}{sigma}{sub T}({Delta}{lambda}/{lambda}{sub {alpha}}){sup -2}[1 + 3.792({Delta}{lambda}/{lambda}{sub {alpha}})], where f{sub 12} and {sigma}{sub T} are the oscillator strength of Ly{alpha} and the Thomson scattering cross section, respectively. In terms of {Delta}{lambda}{sub 2} {identical_to} {lambda} - {lambda}{sub {beta}} in the vicinity of Ly{beta}, the total scattering cross section, given as the sum of cross sections for Rayleigh and Raman scattering, is shown to be {sigma}({lambda}) {approx_equal} {sigma}{sub T}(0.5f{sub 13}){sup 2}(1 + R{sub 0})({Delta}{lambda}{sub 2}/{lambda}{sub {beta}}){sup -2}[1 - 24.68({Delta}{lambda}{sub 2}/{lambda}{sub {beta}})] with f{sub 13} and the factor R{sub 0} = 0.1342 being the oscillator strength for Ly{beta} and the ratio of the Raman cross section to Rayleigh cross section, respectively. A redward asymmetry develops around Ly{alpha}, whereas a blue asymmetry is obtained for Ly{beta}. The absorption center shifts are found to be almost proportional to the neutral hydrogen column density.« less
Measurement of heat load density profile on acceleration grid in MeV-class negative ion accelerator.
Hiratsuka, Junichi; Hanada, Masaya; Kojima, Atsushi; Umeda, Naotaka; Kashiwagi, Mieko; Miyamoto, Kenji; Yoshida, Masafumi; Nishikiori, Ryo; Ichikawa, Masahiro; Watanabe, Kazuhiro; Tobari, Hiroyuki
2016-02-01
To understand the physics of the negative ion extraction/acceleration, the heat load density profile on the acceleration grid has been firstly measured in the ITER prototype accelerator where the negative ions are accelerated to 1 MeV with five acceleration stages. In order to clarify the profile, the peripheries around the apertures on the acceleration grid were separated into thermally insulated 34 blocks with thermocouples. The spatial resolution is as low as 3 mm and small enough to measure the tail of the beam profile with a beam diameter of ∼16 mm. It was found that there were two peaks of heat load density around the aperture. These two peaks were also clarified to be caused by the intercepted negative ions and secondary electrons from detailed investigation by changing the beam optics and gas density profile. This is the first experimental result, which is useful to understand the trajectories of these particles.
Overview of the negative ion based neutral beam injectors for ITER
DOE Office of Scientific and Technical Information (OSTI.GOV)
Schunke, B., E-mail: email@none.edu; Boilson, D.; Chareyre, J.
2016-02-15
The ITER baseline foresees 2 Heating Neutral Beams (HNB’s) based on 1 MeV 40 A D{sup −} negative ion accelerators, each capable of delivering 16.7 MW of deuterium atoms to the DT plasma, with an optional 3rd HNB injector foreseen as a possible upgrade. In addition, a dedicated diagnostic neutral beam will be injecting ≈22 A of H{sup 0} at 100 keV as the probe beam for charge exchange recombination spectroscopy. The integration of the injectors into the ITER plant is nearly finished necessitating only refinements. A large number of components have passed the final design stage, manufacturing has started,more » and the essential test beds—for the prototype route chosen—will soon be ready to start.« less
The preconditioned Gauss-Seidel method faster than the SOR method
NASA Astrophysics Data System (ADS)
Niki, Hiroshi; Kohno, Toshiyuki; Morimoto, Munenori
2008-09-01
In recent years, a number of preconditioners have been applied to linear systems [A.D. Gunawardena, S.K. Jain, L. Snyder, Modified iterative methods for consistent linear systems, Linear Algebra Appl. 154-156 (1991) 123-143; T. Kohno, H. Kotakemori, H. Niki, M. Usui, Improving modified Gauss-Seidel method for Z-matrices, Linear Algebra Appl. 267 (1997) 113-123; H. Kotakemori, K. Harada, M. Morimoto, H. Niki, A comparison theorem for the iterative method with the preconditioner (I+Smax), J. Comput. Appl. Math. 145 (2002) 373-378; H. Kotakemori, H. Niki, N. Okamoto, Accelerated iteration method for Z-matrices, J. Comput. Appl. Math. 75 (1996) 87-97; M. Usui, H. Niki, T.Kohno, Adaptive Gauss-Seidel method for linear systems, Internat. J. Comput. Math. 51(1994)119-125 [10
A fast reconstruction algorithm for fluorescence optical diffusion tomography based on preiteration.
Song, Xiaolei; Xiong, Xiaoyun; Bai, Jing
2007-01-01
Fluorescence optical diffusion tomography in the near-infrared (NIR) bandwidth is considered to be one of the most promising ways for noninvasive molecular-based imaging. Many reconstructive approaches to it utilize iterative methods for data inversion. However, they are time-consuming and they are far from meeting the real-time imaging demands. In this work, a fast preiteration algorithm based on the generalized inverse matrix is proposed. This method needs only one step of matrix-vector multiplication online, by pushing the iteration process to be executed offline. In the preiteration process, the second-order iterative format is employed to exponentially accelerate the convergence. Simulations based on an analytical diffusion model show that the distribution of fluorescent yield can be well estimated by this algorithm and the reconstructed speed is remarkably increased.
Noniterative Multireference Coupled Cluster Methods on Heterogeneous CPU-GPU Systems
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bhaskaran-Nair, Kiran; Ma, Wenjing; Krishnamoorthy, Sriram
2013-04-09
A novel parallel algorithm for non-iterative multireference coupled cluster (MRCC) theories, which merges recently introduced reference-level parallelism (RLP) [K. Bhaskaran-Nair, J.Brabec, E. Aprà, H.J.J. van Dam, J. Pittner, K. Kowalski, J. Chem. Phys. 137, 094112 (2012)] with the possibility of accelerating numerical calculations using graphics processing unit (GPU) is presented. We discuss the performance of this algorithm on the example of the MRCCSD(T) method (iterative singles and doubles and perturbative triples), where the corrections due to triples are added to the diagonal elements of the MRCCSD (iterative singles and doubles) effective Hamiltonian matrix. The performance of the combined RLP/GPU algorithmmore » is illustrated on the example of the Brillouin-Wigner (BW) and Mukherjee (Mk) state-specific MRCCSD(T) formulations.« less
Acceleration of linear stationary iterative processes in multiprocessor computers. II
DOE Office of Scientific and Technical Information (OSTI.GOV)
Romm, Ya.E.
1982-05-01
For pt.I, see Kibernetika, vol.18, no.1, p.47 (1982). For pt.I, see Cybernetics, vol.18, no.1, p.54 (1982). Considers a reduced system of linear algebraic equations x=ax+b, where a=(a/sub ij/) is a real n*n matrix; b is a real vector with common euclidean norm >>>. It is supposed that the existence and uniqueness of solution det (0-a) not equal to e is given, where e is a unit matrix. The linear iterative process converging to x x/sup (k+1)/=fx/sup (k)/, k=0, 1, 2, ..., where the operator f translates r/sup n/ into r/sup n/. In considering implementation of the iterative process (ip) inmore » a multiprocessor system, it is assumed that the number of processors is constant, and are various values of the latter investigated; it is assumed in addition, that the processors perform elementary binary arithmetic operations of addition and multiestimates only include the time of execution of arithmetic operations. With any paralleling of individual iteration, the execution time of the ip is proportional to the number of sequential steps k+1. The author sets the task of reducing the number of sequential steps in the ip so as to execute it in a time proportional to a value smaller than k+1. He also sets the goal of formulating a method of accelerated bit serial-parallel execution of each successive step of the ip, with, in the modification sought, a reduced number of steps in a time comparable to the operation time of logical elements. 6 references.« less
The ITER project construction status
NASA Astrophysics Data System (ADS)
Motojima, O.
2015-10-01
The pace of the ITER project in St Paul-lez-Durance, France is accelerating rapidly into its peak construction phase. With the completion of the B2 slab in August 2014, which will support about 400 000 metric tons of the tokamak complex structures and components, the construction is advancing on a daily basis. Magnet, vacuum vessel, cryostat, thermal shield, first wall and divertor structures are under construction or in prototype phase in the ITER member states of China, Europe, India, Japan, Korea, Russia, and the United States. Each of these member states has its own domestic agency (DA) to manage their procurements of components for ITER. Plant systems engineering is being transformed to fully integrate the tokamak and its auxiliary systems in preparation for the assembly and operations phase. CODAC, diagnostics, and the three main heating and current drive systems are also progressing, including the construction of the neutral beam test facility building in Padua, Italy. The conceptual design of the Chinese test blanket module system for ITER has been completed and those of the EU are well under way. Significant progress has been made addressing several outstanding physics issues including disruption load characterization, prediction, avoidance, and mitigation, first wall and divertor shaping, edge pedestal and SOL plasma stability, fuelling and plasma behaviour during confinement transients and W impurity transport. Further development of the ITER Research Plan has included a definition of the required plant configuration for 1st plasma and subsequent phases of ITER operation as well as the major plasma commissioning activities and the needs of the accompanying R&D program to ITER construction by the ITER parties.
NASA Astrophysics Data System (ADS)
Trujillo Bueno, Javier; Manso Sainz, Rafael
1999-05-01
This paper shows how to generalize to non-LTE polarization transfer some operator splitting methods that were originally developed for solving unpolarized transfer problems. These are the Jacobi-based accelerated Λ-iteration (ALI) method of Olson, Auer, & Buchler and the iterative schemes based on Gauss-Seidel and successive overrelaxation (SOR) iteration of Trujillo Bueno and Fabiani Bendicho. The theoretical framework chosen for the formulation of polarization transfer problems is the quantum electrodynamics (QED) theory of Landi Degl'Innocenti, which specifies the excitation state of the atoms in terms of the irreducible tensor components of the atomic density matrix. This first paper establishes the grounds of our numerical approach to non-LTE polarization transfer by concentrating on the standard case of scattering line polarization in a gas of two-level atoms, including the Hanle effect due to a weak microturbulent and isotropic magnetic field. We begin demonstrating that the well-known Λ-iteration method leads to the self-consistent solution of this type of problem if one initializes using the ``exact'' solution corresponding to the unpolarized case. We show then how the above-mentioned splitting methods can be easily derived from this simple Λ-iteration scheme. We show that our SOR method is 10 times faster than the Jacobi-based ALI method, while our implementation of the Gauss-Seidel method is 4 times faster. These iterative schemes lead to the self-consistent solution independently of the chosen initialization. The convergence rate of these iterative methods is very high; they do not require either the construction or the inversion of any matrix, and the computing time per iteration is similar to that of the Λ-iteration method.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Abulencia, A.; Acosta, D.; Adelman, Jahred A.
2006-01-01
The authors present the first observation of the baryon decay {Lambda}{sub b}{sup 0} {yields} {Lambda}{sub c}{sup +} {pi}{sup -} followed by {Lambda}{sub c}{sup +} {yields} pK{sup -} {pi}{sup +} in 106 pb{sup -1} p{bar p} collisions at {radical}s = 1.96 TeV in the CDF experiment. IN order to reduce systematic error, the measured rate for {Lambda}{sub b}{sup 0} decay is normalized to the kinematically similar meson decay {bar B}{sup 0} {yields} D{sup +}{pi}{sup -} followed by D{sup +} {yields} {pi}{sup +}K{sup -}{pi}{sup +}. They report the ratio of production cross sections ({sigma}) times the ratio of branching fractions ({Beta}) formore » the momentum region integrated above p{sub T} > 6 GeV/c and pseudorapidity range |{eta}| < 1.3: {sigma}(p{bar p} {yields} {Lambda}{sub b}{sup 0}X)/{sigma}(p{bar p} {yields} {bar B}{sup 0} X) x {Beta}({Lambda}{sub b}{sup 0} {yields} {Lambda}{sub c}{sup +}{pi}{sup -})/{Beta}({bar B}{sup 0} {yields} D{sup +}{pi}{sup -}) = 0.82 {+-} 0.08(stat) {+-} 0.11(syst) {+-} 0.22 ({Beta}({Lambda}{sub c}{sup +} {yields} pK{sup -} {pi}{sup +})).« less
Inhibitory effect of tocotrienol on eukaryotic DNA polymerase {lambda} and angiogenesis
DOE Office of Scientific and Technical Information (OSTI.GOV)
Mizushina, Yoshiyuki; Nakagawa, Kiyotaka; Shibata, Akira
2006-01-20
Tocotrienols, vitamin E compounds that have an unsaturated side chain with three double bonds, selectively inhibited the activity of mammalian DNA polymerase {lambda} (pol {lambda}) in vitro. These compounds did not influence the activities of replicative pols such as {alpha}, {delta}, and {epsilon}, or even the activity of pol {beta} which is thought to have a very similar three-dimensional structure to the pol {beta}-like region of pol {lambda}. Since {delta}-tocotrienol had the strongest inhibitory effect among the four ({alpha}- to {delta}-) tocotrienols, the isomer's structure might be an important factor in the inhibition of pol {lambda}. The inhibitory effect ofmore » {delta}-tocotrienol on both intact pol {lambda} (residues 1-575) and a truncated pol {lambda} lacking the N-terminal BRCA1 C-terminus (BRCT) domain (residues 133-575, del-1 pol {lambda}) was dose-dependent, with 50% inhibition observed at a concentration of 18.4 and 90.1 {mu}M, respectively. However, del-2 pol {lambda} (residues 245-575) containing the C-terminal pol {beta}-like region was unaffected. Tocotrienols also inhibited the proliferation of and formation of tubes by bovine aortic endothelial cells, with {delta}-tocotrienol having the greatest effect. These results indicated that tocotrienols targeted both pol {lambda} and angiogenesis as anti-cancer agents. The relationship between the inhibition of pol {lambda} and anti-angiogenesis by {delta}-tocotrienol was discussed.« less
The formation of low-ionization emission in the halo of NGC 891
NASA Technical Reports Server (NTRS)
Sokolowski, James; Bland-Hawthorn, Jonathan
1993-01-01
Imaging and Spectroscopic study first revealed the presence of a diffuse ionized medium (DIM), having unusual excitation, pervading the lower halo of the edge-on spiral galaxy NGC 891. Emission from this DIM is strongest northeast of the nucleus, at radii between 2 and 8 kpc (hereafter region 1). The (N2)(lambda)6583/H(alpha) and (S2)(lambda) (lambda)6716,6731/H(alpha) ratios increase dramatically with z in region 1, from 0.6 and 0.5 respectively at z is approximately equal to 500 pc to 1.1 and 1.0 at z is approximately equal to 1 kpc, while nondetections of (O1)(lambda)6300 and (O3)(lambda)5007 emission yield upper limits of (O1)(lambda)6300/H(alpha) less than or equal to 0.05 and (O3)(lambda)5007/H(alpha) less than or equal to 0.15 for z less than 1 kpc. Previous photoionization models, using the radiation field from disk O and B stars, have been successful in reproducing the elevated (N2)(lambda)6583/H(alpha) and (S2)(lambda)(lambda)6716.6731/H(alpha) ratios observed. However, these radiation bounded models also produce significant (O3)(lambda)5007 emission, in conflict with the observed upper limit. Here, we report the results of new, matter bounded models for the photoionization of the DIM in region 1 of NGC 891.
1983-03-01
values of these functions on the two sides of the slits. The acceleration parameters for the iteration at each point are in the field array WACC (I,J...code will calculate a locally optimum value at each point in the field, these values being placed in the field array WACC . This calculation is...changes in x and y, are calculated by calling subroutine ERROR.) The acceleration parameter is placed in the field 65 array WACC . The addition to the
Pull-in instability of paddle-type and double-sided NEMS sensors under the accelerating force
NASA Astrophysics Data System (ADS)
Keivani, M.; Khorsandi, J.; Mokhtari, J.; Kanani, A.; Abadian, N.; Abadyan, M.
2016-02-01
Paddle-type and double-sided nanostructures are potential for use as accelerometers in flying vehicles and aerospace applications. Herein the pull-in instability of the cantilever paddle-type and double-sided sensors in the Casimir regime are investigated under the acceleration. The D'Alembert principle is employed to transform the accelerating system into an equivalent static system by incorporating the accelerating force. Based on the couple stress theory (CST), the size-dependent constitutive equations of the sensors are derived. The governing nonlinear equations are solved by two approaches, i.e. modified variational iteration method and finite difference method. The influences of the Casimir force, geometrical parameters, acceleration and the size phenomenon on the instability performance have been demonstrated. The obtained results are beneficial to design and fabricate paddle-type and double-sided accelerometers.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Abazov V. M.; Abbott, B.; Acharya, B. S.
2012-06-07
We measure the {Lambda}{sub b}{sup 0} lifetime in the fully reconstructed decay {Lambda}{sub b}{sup 0} {yields} J/{psi}{Lambda}{sup 0} using 10.4 fb{sup -1} of p{bar p} collisions collected with the D0 detector at {radical}s = 1.96 TeV. The lifetime of the topologically similar decay channel B{sup 0} {yields} J/{psi}K{sub S}{sup 0} is also measured. We obtain {tau}({Lambda}{sub b}{sup 0}) = 1.303 {+-} 0.075(stat) {+-} 0.035(syst) ps and {tau}(B{sup 0}) = 1.508 {+-} 0.025(stat) {+-} 0.043(syst) ps. Using these measurements, we determine the lifetime ratio of {tau}({Lambda}{sub b}{sup 0})/{tau}(B{sup 0}) = 0.864 {+-} 0.052(stat) {+-} 0.033(syst).
Flisiak, Robert; Shiffman, Mitchell; Arenas, Juan; Cheinquer, Hugo; Nikitin, Igor; Dong, Yuping; Rana, Khurram; Srinivasan, Subasree
2016-01-01
A randomized, double-blind, multinational, phase 3 study was conducted comparing the efficacy and safety of peginterferon lambda-1a (Lambda)/ribavirin (RBV)/telaprevir (TVR) vs. peginterferon alfa-2a (Alfa)/RBV/TVR in patients with chronic hepatitis C virus (HCV) genotype-1 (GT-1) infection. Patients (treatment-naïve or relapsers on prior Alfa/RBV treatment) were randomly assigned in a 2:1 ratio to receive Lambda/RBV/TVR or Alfa/RBV/TVR. Total duration of treatment was either 24 or 48 weeks (response-guided treatment), with TVR administered for the first 12 weeks. The primary endpoint was the proportion of patients who achieved a sustained virologic response at post treatment week 12 (SVR12), which was tested for noninferiority of Lambda/RBV/TVR. A total of 838 patients were enrolled, and 617 were treated; 411 and 206 patients received Lambda/RBV/TVR and Alfa/RBV/TVR, respectively. The majority of patients were treatment-naïve, with HCV GT-1b and a high baseline viral load (≥800,000 IU/mL). Less than 10% of patients had cirrhosis (Lambda, 7.5%; Alfa, 6.8%). Lambda/RBV/TVR did not meet the criterion for noninferiority (lower bound of the treatment difference interval was -12.3%); the SVR12 in all patients (modified intent-to-treat) was 76.2% in the Lambda arm and 82.0% in the Alfa arm. Overall, the frequency of adverse events in each arm was comparable (Lambda, 91.7%; Alfa, 97.1%). As expected based on the safety profile of the 2 interferons, there were more hepatobiliary events observed in the Lambda arm and more hematologic events in the Alfa arm. In this comparison of Lambda/RBV/TVR and Alfa/RBV/TVR in patients who were treatment-naïve or had relapsed on prior Alfa/RBV treatment, Lambda failed to demonstrate noninferiority based on SVR12 results. Treatment with Lambda/RBV/TVR was associated with a higher incidence of relapse. More patients discontinued Lambda/RBV/TVR treatment during the first 4 weeks of study treatment, mainly due to hepatobiliary-related events, and more Lambda patients were lost to follow-up.
On the Convergence of an Implicitly Restarted Arnoldi Method
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lehoucq, Richard B.
We show that Sorensen's [35] implicitly restarted Arnoldi method (including its block extension) is simultaneous iteration with an implicit projection step to accelerate convergence to the invariant subspace of interest. By using the geometric convergence theory for simultaneous iteration due to Watkins and Elsner [43], we prove that an implicitly restarted Arnoldi method can achieve a super-linear rate of convergence to the dominant invariant subspace of a matrix. Moreover, we show how an IRAM computes a nested sequence of approximations for the partial Schur decomposition associated with the dominant invariant subspace of a matrix.
Apparatus and method for closed-loop control of reactor power in minimum time
Bernard, Jr., John A.
1988-11-01
Closed-loop control law for altering the power level of nuclear reactors in a safe manner and without overshoot and in minimum time. Apparatus is provided for moving a fast-acting control element such as a control rod or a control drum for altering the nuclear reactor power level. A computer computes at short time intervals either the function: .rho.=(.beta.-.rho.).omega.-.lambda..sub.e '.rho.-.SIGMA..beta..sub.i (.lambda..sub.i -.lambda..sub.e ')+l* .omega.+l* [.omega..sup.2 +.lambda..sub.e '.omega.] or the function: .rho.=(.beta.-.rho.).omega.-.lambda..sub.e .rho.-(.lambda..sub.e /.lambda..sub.e)(.beta.-.rho.)+l* .omega.+l* [.omega..sup.2 +.lambda..sub.e .omega.-(.lambda..sub.e /.lambda..sub.e).omega.] These functions each specify the rate of change of reactivity that is necessary to achieve a specified rate of change of reactor power. The direction and speed of motion of the control element is altered so as to provide the rate of reactivity change calculated using either or both of these functions thereby resulting in the attainment of a new power level without overshoot and in minimum time. These functions are computed at intervals of approximately 0.01-1.0 seconds depending on the specific application.
Solution of a tridiagonal system of equations on the finite element machine
NASA Technical Reports Server (NTRS)
Bostic, S. W.
1984-01-01
Two parallel algorithms for the solution of tridiagonal systems of equations were implemented on the Finite Element Machine. The Accelerated Parallel Gauss method, an iterative method, and the Buneman algorithm, a direct method, are discussed and execution statistics are presented.
Sartori, E; Pavei, M; Marcuzzi, D; Zaccaria, P
2014-02-01
The beam formation and acceleration of the ITER neutral beam injector will be studied in the full-scale ion source, Source for Production of Ions of Deuterium Extracted from a RF plasma (SPIDER). It will be able to sustain 40 A deuterium ion beam during 1-h pulses. The operating conditions of its multi-aperture electrodes will diverge from ideality, as a consequence of inhomogeneous heating and thermally induced deformations in the support structure of the extraction and acceleration grids, which operate at different temperatures. Meeting the requirements on the aperture alignment and distance between the grids with such a large number of apertures (1280) and the huge support structures constitute a challenge. Examination of the structure thermal deformation in transient and steady conditions has been carried out, evaluating their effect on the beam performance: the paper describes the analyses and the solutions proposed to mitigate detrimental effects.
NASA Technical Reports Server (NTRS)
Jothiprasad, Giridhar; Mavriplis, Dimitri J.; Caughey, David A.; Bushnell, Dennis M. (Technical Monitor)
2002-01-01
The efficiency gains obtained using higher-order implicit Runge-Kutta schemes as compared with the second-order accurate backward difference schemes for the unsteady Navier-Stokes equations are investigated. Three different algorithms for solving the nonlinear system of equations arising at each timestep are presented. The first algorithm (NMG) is a pseudo-time-stepping scheme which employs a non-linear full approximation storage (FAS) agglomeration multigrid method to accelerate convergence. The other two algorithms are based on Inexact Newton's methods. The linear system arising at each Newton step is solved using iterative/Krylov techniques and left preconditioning is used to accelerate convergence of the linear solvers. One of the methods (LMG) uses Richardson's iterative scheme for solving the linear system at each Newton step while the other (PGMRES) uses the Generalized Minimal Residual method. Results demonstrating the relative superiority of these Newton's methods based schemes are presented. Efficiency gains as high as 10 are obtained by combining the higher-order time integration schemes with the more efficient nonlinear solvers.
Real-Time Compressive Sensing MRI Reconstruction Using GPU Computing and Split Bregman Methods
Smith, David S.; Gore, John C.; Yankeelov, Thomas E.; Welch, E. Brian
2012-01-01
Compressive sensing (CS) has been shown to enable dramatic acceleration of MRI acquisition in some applications. Being an iterative reconstruction technique, CS MRI reconstructions can be more time-consuming than traditional inverse Fourier reconstruction. We have accelerated our CS MRI reconstruction by factors of up to 27 by using a split Bregman solver combined with a graphics processing unit (GPU) computing platform. The increases in speed we find are similar to those we measure for matrix multiplication on this platform, suggesting that the split Bregman methods parallelize efficiently. We demonstrate that the combination of the rapid convergence of the split Bregman algorithm and the massively parallel strategy of GPU computing can enable real-time CS reconstruction of even acquisition data matrices of dimension 40962 or more, depending on available GPU VRAM. Reconstruction of two-dimensional data matrices of dimension 10242 and smaller took ~0.3 s or less, showing that this platform also provides very fast iterative reconstruction for small-to-moderate size images. PMID:22481908
Real-Time Compressive Sensing MRI Reconstruction Using GPU Computing and Split Bregman Methods.
Smith, David S; Gore, John C; Yankeelov, Thomas E; Welch, E Brian
2012-01-01
Compressive sensing (CS) has been shown to enable dramatic acceleration of MRI acquisition in some applications. Being an iterative reconstruction technique, CS MRI reconstructions can be more time-consuming than traditional inverse Fourier reconstruction. We have accelerated our CS MRI reconstruction by factors of up to 27 by using a split Bregman solver combined with a graphics processing unit (GPU) computing platform. The increases in speed we find are similar to those we measure for matrix multiplication on this platform, suggesting that the split Bregman methods parallelize efficiently. We demonstrate that the combination of the rapid convergence of the split Bregman algorithm and the massively parallel strategy of GPU computing can enable real-time CS reconstruction of even acquisition data matrices of dimension 4096(2) or more, depending on available GPU VRAM. Reconstruction of two-dimensional data matrices of dimension 1024(2) and smaller took ~0.3 s or less, showing that this platform also provides very fast iterative reconstruction for small-to-moderate size images.
Parallel Reconstruction Using Null Operations (PRUNO)
Zhang, Jian; Liu, Chunlei; Moseley, Michael E.
2011-01-01
A novel iterative k-space data-driven technique, namely Parallel Reconstruction Using Null Operations (PRUNO), is presented for parallel imaging reconstruction. In PRUNO, both data calibration and image reconstruction are formulated into linear algebra problems based on a generalized system model. An optimal data calibration strategy is demonstrated by using Singular Value Decomposition (SVD). And an iterative conjugate- gradient approach is proposed to efficiently solve missing k-space samples during reconstruction. With its generalized formulation and precise mathematical model, PRUNO reconstruction yields good accuracy, flexibility, stability. Both computer simulation and in vivo studies have shown that PRUNO produces much better reconstruction quality than autocalibrating partially parallel acquisition (GRAPPA), especially under high accelerating rates. With the aid of PRUO reconstruction, ultra high accelerating parallel imaging can be performed with decent image quality. For example, we have done successful PRUNO reconstruction at a reduction factor of 6 (effective factor of 4.44) with 8 coils and only a few autocalibration signal (ACS) lines. PMID:21604290
NASA Astrophysics Data System (ADS)
Nouizi, F.; Erkol, H.; Luk, A.; Marks, M.; Unlu, M. B.; Gulsen, G.
2016-10-01
We previously introduced photo-magnetic imaging (PMI), an imaging technique that illuminates the medium under investigation with near-infrared light and measures the induced temperature increase using magnetic resonance thermometry (MRT). Using a multiphysics solver combining photon migration and heat diffusion, PMI models the spatiotemporal distribution of temperature variation and recovers high resolution optical absorption images using these temperature maps. In this paper, we present a new fast non-iterative reconstruction algorithm for PMI. This new algorithm uses analytic methods during the resolution of the forward problem and the assembly of the sensitivity matrix. We validate our new analytic-based algorithm with the first generation finite element method (FEM) based reconstruction algorithm previously developed by our team. The validation is performed using, first synthetic data and afterwards, real MRT measured temperature maps. Our new method accelerates the reconstruction process 30-fold when compared to a single iteration of the FEM-based algorithm.
On Spectral Invariance of Single Scattering Albedo for Weakly Absorbing Wavelengths
NASA Technical Reports Server (NTRS)
Marshak, Alexander; Knyazikhin, Yuri; Chiu, J. Christine; Wiscombe, Warren J.
2011-01-01
This note shows that for water droplets at weakly absorbing wavelengths, the ratio omega(sub O lambda(r))/omega(sub O lambda(r(sub O)) of two single scattering albedo spectra, omega(sub O lambda(r) and omega(sub O lambda(r (sub O)), is a linear function of omega(sub O lambda(r). The slope and intercept of the linear function are wavelength independent and sum to unity. This relationship allows for a representation of any single scattering albedo omega(sub O lambda(r) via one known spectrum omega(sub O lambda(r(sub O)). The note provides a simple physical explanation of the discovered relationship. In addition to water droplets, similar linear relationships were found for the single scattering albedo of non-spherical ice crystals.
Freeman, J; Baglino, S; Friborg, J; Kraft, Z; Gray, T; Hill, M; McPhee, F; Hillson, J; Lopez-Talavera, J C; Wind-Rotolo, M
2014-06-01
Pegylated interferon-lambda-1a (Lambda), a type III interferon (IFN) in clinical development for the treatment of chronic HCV infection, has shown comparable efficacy and an improved safety profile to a regimen based on pegylated IFN alfa-2a (alfa). To establish a mechanistic context for this improved profile, we investigated the ex vivo effects of Lambda and alfa on cytokine and chemokine release, and on expression of IFN-stimulated genes (ISGs) in primary human hepatocytes and peripheral blood mononuclear cells (PBMCs) from healthy subjects. Our findings were further compared with changes observed in blood analysed from HCV-infected patients treated with Lambda or alfa in clinical studies. mRNA transcript and protein expression of the IFN-λ-limiting receptor subunit was lower compared with IFN-α receptor subunits in all cell types. Upon stimulation, alfa and Lambda induced ISG expression in hepatocytes and PBMCs, although in PBMCs Lambda-induced ISG expression was modest. Furthermore, alfa and Lambda induced release of cytokines and chemokines from hepatocytes and PBMCs, although differences in their kinetics of induction were observed. In HCV-infected patients, alfa treatment induced ISG expression in whole blood after single and repeat dosing. Lambda treatment induced modest ISG expression after single dosing and showed no induction after repeat dosing. Alfa and Lambda treatment increased IP-10, iTAC, IL-6, MCP-1 and MIP-1β levels in serum, with alfa inducing higher levels of all mediators compared with Lambda. Overall, ex vivo and in vivo induction profiles reported in this analysis strongly correlate with clinical observations of fewer related adverse events for Lambda vs those typically associated with alfa. © 2014 John Wiley & Sons Ltd.
Environmental chemistry, ecotoxicity, and fate of lambda-cyhalothrin.
He, Li-Ming; Troiano, John; Wang, Albert; Goh, Kean
2008-01-01
Lambda-cyhalothrin is a pyrethroid insecticide used for controlling pest insects in agriculture, public health, and in construction and households. Lambda-cyhalothrin is characterized by low vapor pressure and a low Henry's law constant but by a high octanol-water partition coefficient (K(ow)) and high water-solid-organic carbon partition coefficient (K(oc)) values. Lambda-cyhalothrin is quite stable in water at pH < 8, whereas it hydrolyzes to form HCN and aldehyde under alkaline conditions. Although lambda-cyhalothrin is relatively photostable under natural irradiation, with a half-life > 3 wk, its photolysis process is fast under UV irradiation, with a half-life < 10 min. The fate of lambda-cyhalothrin in aquatic ecosystems depends on the nature of system components such as suspended solids (mineral and organic particulates) and aquatic organisms (algae, macrophytes, or aquatic animals). Lambda-cyhalothrin residues dissolved in water decrease rapidly if suspended solids and/or aquatic organisms are present because lambda-cyhalothrin molecules are strongly adsorbed by particulates and plants. Adsorbed lambda-cyhalothrin molecules show decreased degradation rates because they are less accessible to breakdown than free molecules in the water column. On the other hand, lambda-cyhalothrin adsorbed to suspended solids or bottom sediments may provide a mechanism to mitigate its acute toxicity to aquatic organisms by reducing their short-term bioavailability in the water column. The widespread use of lambda-cyhalothrin has resulted in residues in sediment, which have been found to be toxic to aquatic organisms including fish and amphipods. Mitigation measures have been used to reduce the adverse impact of lambda-cyhalothrin contributed from agricultural or urban runoff. Mitigation may be achieved by reducing the quantity of runoff and suspended solid content in runoff through wetlands, detention ponds, or vegetated ditches.
Hesford, Andrew J.; Chew, Weng C.
2010-01-01
The distorted Born iterative method (DBIM) computes iterative solutions to nonlinear inverse scattering problems through successive linear approximations. By decomposing the scattered field into a superposition of scattering by an inhomogeneous background and by a material perturbation, large or high-contrast variations in medium properties can be imaged through iterations that are each subject to the distorted Born approximation. However, the need to repeatedly compute forward solutions still imposes a very heavy computational burden. To ameliorate this problem, the multilevel fast multipole algorithm (MLFMA) has been applied as a forward solver within the DBIM. The MLFMA computes forward solutions in linear time for volumetric scatterers. The typically regular distribution and shape of scattering elements in the inverse scattering problem allow the method to take advantage of data redundancy and reduce the computational demands of the normally expensive MLFMA setup. Additional benefits are gained by employing Kaczmarz-like iterations, where partial measurements are used to accelerate convergence. Numerical results demonstrate both the efficiency of the forward solver and the successful application of the inverse method to imaging problems with dimensions in the neighborhood of ten wavelengths. PMID:20707438
Towards plasma cleaning of ITER first mirrors
NASA Astrophysics Data System (ADS)
Moser, L.; Marot, L.; Eren, B.; Steiner, R.; Mathys, D.; Leipold, F.; Reichle, R.; Meyer, E.
2015-06-01
To avoid reflectivity losses in ITER's optical diagnostic systems, on-site cleaning of metallic first mirrors via plasma sputtering is foreseen to remove deposit build-ups migrating from the main wall. In this work, the influence of aluminium and tungsten deposits on the reflectivity of molybdenum mirrors as well as the possibility to clean them with plasma exposure is investigated. Porous ITER-like deposits are grown to mimic the edge conditions expected in ITER, and a severe degradation in the specular reflectivity is observed as these deposits build up on the mirror surface. In addition, dense oxide films are produced for comparisons with porous films. The composition, morphology and crystal structure of several films were characterized by means of scanning electron microscopy, x-ray photoelectron spectroscopy, x-ray diffraction and secondary ion mass spectrometry. The cleaning of the deposits and the restoration of the mirrors' optical properties are possible either with a Kaufman source or radio frequency directly applied to the mirror (or radio frequency plasma generated directly around the mirror surface). Accelerating ions of an external plasma source through a direct current applied onto the mirror does not remove deposits composed of oxides. A possible implementation of plasma cleaning in ITER is addressed.
NASA Astrophysics Data System (ADS)
Zhou, Yuzhi; Wang, Han; Liu, Yu; Gao, Xingyu; Song, Haifeng
2018-03-01
The Kerker preconditioner, based on the dielectric function of homogeneous electron gas, is designed to accelerate the self-consistent field (SCF) iteration in the density functional theory calculations. However, a question still remains regarding its applicability to the inhomogeneous systems. We develop a modified Kerker preconditioning scheme which captures the long-range screening behavior of inhomogeneous systems and thus improves the SCF convergence. The effectiveness and efficiency is shown by the tests on long-z slabs of metals, insulators, and metal-insulator contacts. For situations without a priori knowledge of the system, we design the a posteriori indicator to monitor if the preconditioner has suppressed charge sloshing during the iterations. Based on the a posteriori indicator, we demonstrate two schemes of the self-adaptive configuration for the SCF iteration.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cai, Yunfeng, E-mail: yfcai@math.pku.edu.cn; Department of Computer Science, University of California, Davis 95616; Bai, Zhaojun, E-mail: bai@cs.ucdavis.edu
2013-12-15
The iterative diagonalization of a sequence of large ill-conditioned generalized eigenvalue problems is a computational bottleneck in quantum mechanical methods employing a nonorthogonal basis for ab initio electronic structure calculations. We propose a hybrid preconditioning scheme to effectively combine global and locally accelerated preconditioners for rapid iterative diagonalization of such eigenvalue problems. In partition-of-unity finite-element (PUFE) pseudopotential density-functional calculations, employing a nonorthogonal basis, we show that the hybrid preconditioned block steepest descent method is a cost-effective eigensolver, outperforming current state-of-the-art global preconditioning schemes, and comparably efficient for the ill-conditioned generalized eigenvalue problems produced by PUFE as the locally optimal blockmore » preconditioned conjugate-gradient method for the well-conditioned standard eigenvalue problems produced by planewave methods.« less
Using parallel banded linear system solvers in generalized eigenvalue problems
NASA Technical Reports Server (NTRS)
Zhang, Hong; Moss, William F.
1993-01-01
Subspace iteration is a reliable and cost effective method for solving positive definite banded symmetric generalized eigenproblems, especially in the case of large scale problems. This paper discusses an algorithm that makes use of two parallel banded solvers in subspace iteration. A shift is introduced to decompose the banded linear systems into relatively independent subsystems and to accelerate the iterations. With this shift, an eigenproblem is mapped efficiently into the memories of a multiprocessor and a high speed-up is obtained for parallel implementations. An optimal shift is a shift that balances total computation and communication costs. Under certain conditions, we show how to estimate an optimal shift analytically using the decay rate for the inverse of a banded matrix, and how to improve this estimate. Computational results on iPSC/2 and iPSC/860 multiprocessors are presented.
Mass and K{lambda} Coupling of the N*(1535)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Liu, B.C.; Graduate School of the Chinese Academy of Sciences, Beijing 100049; Zou, B.S.
2006-02-03
Using a resonance isobar model and an effective Lagrangian approach, from recent BES results on J/{psi}{yields}pp{eta} and {psi}{yields}pK{sup +}{lambda}, we deduce the ratio between effective coupling constants of N*(1535) to K{lambda} and p{eta} to be R{identical_to}g{sub N*(1535)K{lambda}}/g{sub N*(1535)p{eta}}=1.3{+-}0.3. With the previous known value of g{sub N*(1535)p{eta}}, the obtained new value of g{sub N*(1535)K{lambda}} is shown to reproduce recent pp{yields}pK{sup +}{lambda} near-threshold cross section data as well. Taking into account this large N*K{lambda} coupling in the coupled channel Breit-Wigner formula for the N*(1535), its Breit-Wigner mass is found to be around 1400 MeV, much smaller than the previous value of aboutmore » 1535 MeV obtained without including its coupling to K{lambda}. The implication on the nature of N*(1535) is discussed.« less
Radiation Safety System for SPIDER Neutral Beam Accelerator
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sandri, S.; Poggi, C.; Coniglio, A.
2011-12-13
SPIDER (Source for Production of Ion of Deuterium Extracted from RF Plasma only) and MITICA (Megavolt ITER Injector Concept Advanced) are the ITER neutral beam injector (NBI) testing facilities of the PRIMA (Padova Research Injector Megavolt Accelerated) Center. Both injectors accelerate negative deuterium ions with a maximum energy of 1 MeV for MITICA and 100 keV for SPIDER with a maximum beam current of 40 A for both experiments. The SPIDER facility is classified in Italy as a particle accelerator. At present, the design of the radiation safety system for the facility has been completed and the relevant reports havemore » been presented to the Italian regulatory authorities. Before SPIDER can operate, approval must be obtained from the Italian Regulatory Authority Board (IRAB) following a detailed licensing process. In the present work, the main project information and criteria for the SPIDER injector source are reported together with the analysis of hypothetical accidental situations and safety issues considerations. Neutron and photon nuclear analysis is presented, along with special shielding solutions designed to meet Italian regulatory dose limits. The contribution of activated corrosion products (ACP) to external exposure of workers has also been assessed. Nuclear analysis indicates that the photon contribution to worker external exposure is negligible, and the neutron dose can be considered by far the main radiation protection issue. Our results confirm that the injector has no important radiological impact on the population living around the facility.« less
Multi-GPU Accelerated Admittance Method for High-Resolution Human Exposure Evaluation.
Xiong, Zubiao; Feng, Shi; Kautz, Richard; Chandra, Sandeep; Altunyurt, Nevin; Chen, Ji
2015-12-01
A multi-graphics processing unit (GPU) accelerated admittance method solver is presented for solving the induced electric field in high-resolution anatomical models of human body when exposed to external low-frequency magnetic fields. In the solver, the anatomical model is discretized as a three-dimensional network of admittances. The conjugate orthogonal conjugate gradient (COCG) iterative algorithm is employed to take advantage of the symmetric property of the complex-valued linear system of equations. Compared against the widely used biconjugate gradient stabilized method, the COCG algorithm can reduce the solving time by 3.5 times and reduce the storage requirement by about 40%. The iterative algorithm is then accelerated further by using multiple NVIDIA GPUs. The computations and data transfers between GPUs are overlapped in time by using asynchronous concurrent execution design. The communication overhead is well hidden so that the acceleration is nearly linear with the number of GPU cards. Numerical examples show that our GPU implementation running on four NVIDIA Tesla K20c cards can reach 90 times faster than the CPU implementation running on eight CPU cores (two Intel Xeon E5-2603 processors). The implemented solver is able to solve large dimensional problems efficiently. A whole adult body discretized in 1-mm resolution can be solved in just several minutes. The high efficiency achieved makes it practical to investigate human exposure involving a large number of cases with a high resolution that meets the requirements of international dosimetry guidelines.
Chan, Henry L Y; Ahn, Sang Hoon; Chang, Ting-Tsung; Peng, Cheng-Yuan; Wong, David; Coffin, Carla S; Lim, Seng Gee; Chen, Pei-Jer; Janssen, Harry L A; Marcellin, Patrick; Serfaty, Lawrence; Zeuzem, Stefan; Cohen, David; Critelli, Linda; Xu, Dong; Wind-Rotolo, Megan; Cooney, Elizabeth
2016-05-01
Peginterferon lambda-1a (lambda) is a Type-III interferon, which, like alfa interferons, has antiviral activity in vitro against hepatitis B virus (HBV) and hepatitis C virus (HCV); however, lambda has a more limited extra-hepatic receptor distribution. This phase 2b study (LIRA-B) evaluated lambda in patients with chronic HBV infection. Adult HBeAg+ interferon-naive patients were randomized (1:1) to weekly lambda (180 μg) or peginterferon alfa-2a (alfa) for 48 weeks. The primary efficacy endpoint was HBeAg seroconversion at week 24 post-treatment; lambda non-inferiority was demonstrated if the 80% confidence interval (80% CI) lower bound was >-15%. Baseline characteristics were balanced across groups (lambda N=80; alfa N=83). Early on-treatment declines in HBV-DNA and qHBsAg through week 24 were greater with lambda. HBeAg seroconversion rates were comparable for lambda and alfa at week 48 (17.5% vs. 16.9%, respectively); however lambda non-inferiority was not met at week 24 post-treatment (13.8% vs. 30.1%, respectively; lambda vs. alfa 80% CI lower bound -24%). Results for other key secondary endpoints (virologic, serologic, biochemical) and post hoc combined endpoints (HBV-DNA <2000 IU/ml plus HBeAg seroconversion or ALT normalization) mostly favored alfa. Overall adverse events (AE), serious AE, and AE-discontinuation rates were comparable between arms but AE-spectra differed (more cytopenias, flu-like, and musculoskeletal symptoms observed with alfa, more ALT flares and bilirubin elevations seen with lambda). Most on-treatment flares occurred early (weeks 4-12), associated with HBV-DNA decline; all post-treatment flares were preceded by HBV-DNA rise. On-treatment, lambda showed greater early effects on HBV-DNA and qHBsAg, and comparable serologic/virologic responses at end-of-treatment. However, post-treatment, alfa-associated HBeAg seroconversion rates were higher, and key secondary results mostly favored alfa. ClinicalTrials.gov number: NCT01204762. Copyright © 2016 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Barria, Patrizia
2012-01-01
We present the observation of themore » $$\\Lambda^0_b$$ decay into a $$\\Lambda^+_c \\pi^- \\pi^+ \\pi^-$$ final state, in $$p\\bar{p}$$ collisions at $$\\sqrt{s}$$ = 1:96 TeV. The data analyzed were collected by the CDF II detector at the Fermilab Tevatron collider, and correspond to 2:4 $$fb^{-1}$$ of integrated luminosity. We fit the invariant mass distribution of the reconstructed candidates to extract a signal yield of 848 $$\\pm$$ 93 $$\\Lambda^0_b$$ into $$\\Lambda^+_c \\pi^- \\pi^+ \\pi^-$$....« less
NASA Technical Reports Server (NTRS)
Zirin, H.
1975-01-01
Measurements of the lambda 1030 He line in 198 stars are given along with data on other features in that spectral range. Nearly 80% of all G and K stars show some lambda 10830; of these, half are variable and 1/4 show emission. It was confirmed that lambda 10830 is not found in M stars, is weak in F stars, and is particularly strong in close binaries. The line is found in emission in extremely late M and S stars, along with P gamma, but P gamma is not in emission in G and K stars with lambda 10830 emissions. Variable He emission and Ti I emission are found in the RV Tauri variables R Scuti and U Mon. In R Aqr the Fe XIII coronal line lambda 10747 and a line at lambda 11012 which may be singlet He or La II are found, as well as lambda 10830 and P gamma. The nature of coronas or hot chromospheres in the various stars is discussed. It was concluded that the lambda 10830 intensity must be more or less proportional to the energy deposited in the chromosphere corona by non-thermal processes.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chen, Zhe Jay; Bongiorni, Paul; Nath, Ravinder
Purpose: Although several dosimetric characterizations using Monte Carlo simulation and thermoluminescent dosimetry (TLD) have been reported for the new Advantage Pd-103 source (IsoAid, LLC, Port Richey, FL), no AAPM consensus value has been established for the dosimetric parameters of the source. The aim of this work was to perform an additional dose-rate constant ({Lambda}) determination using a recently established photon spectrometry technique (PST) that is independent of the published TLD and Monte Carlo techniques. Methods: Three Model IAPD-103A Advantage Pd-103 sources were used in this study. The relative photon energy spectrum emitted by each source along the transverse axis wasmore » measured using a high-resolution germanium spectrometer designed for low-energy photons. For each source, the dose-rate constant was determined from its emitted energy spectrum. The PST-determined dose-rate constant ({sub PST}{Lambda}) was then compared to those determined by TLD ({sub TLD}{Lambda}) and Monte Carlo ({sub MC}{Lambda}) techniques. A likely consensus {Lambda} value was estimated as the arithmetic mean of the average {Lambda} values determined by each of three different techniques. Results: The average {sub PST}{Lambda} value for the three Advantage sources was found to be (0.676{+-}0.026) cGyh{sup -1} U{sup -1}. Intersource variation in {sub PST}{Lambda} was less than 0.01%. The {sub PST}{Lambda} was within 2% of the reported {sub MC}{Lambda} values determined by PTRAN, EGSnrc, and MCNP5 codes. It was 3.4% lower than the reported {sub TLD}{Lambda}. A likely consensus {Lambda} value was estimated to be (0.688{+-}0.026) cGyh{sup -1} U{sup -1}, similar to the AAPM consensus values recommended currently for the Theragenics (Buford, GA) Model 200 (0.686{+-}0.033) cGyh{sup -1} U{sup -1}, the NASI (Chatsworth, CA) Model MED3633 (0.688{+-}0.033) cGyh{sup -1} U{sup -1}, and the Best Medical (Springfield, VA) Model 2335 (0.685{+-}0.033) cGyh{sup -1} U{sup -1} {sup 103}Pd sources. Conclusions: An independent {Lambda} determination has been performed for the Advantage Pd-103 source. The {sub PST}{Lambda} obtained in this work provides additional information needed for establishing a more accurate consensus {Lambda} value for the Advantage Pd-103 source.« less
Redshift remapping and cosmic acceleration in dark-matter-dominated cosmological models
Wojtak, Radosław; Prada, Francisco
2017-06-21
The standard relation between the cosmological redshift and cosmic scale factor underlies cosmological inference from virtually all kinds of cosmological observations, leading to the emergence of the LambdaCDM cosmological model. This relation is not a fundamental theory and thus observational determination of this function (redshift remapping) should be regarded as an insightful alternative to holding its standard form in analyses of cosmological data. We present non-parametric reconstructions of redshift remapping in dark-matter-dominated models and constraints on cosmological parameters from a joint analysis of all primary cosmological probes including the local measurement of the Hubble constant, Type Ia supernovae, baryonic acousticmore » oscillations (BAO), Planck observations of the cosmic microwave background (CMB) radiation (temperature power spectrum) and cosmic chronometers. The reconstructed redshift remapping points to an additional boost of redshift operating in late epoch of cosmic evolution, but affecting both low-redshift observations and the CMB. The model then predicts a significant difference between the actual Hubble constant, h=0.48±0.02, and its local determination, h obs=0.73±0.02. The ratio of these two values coincides closely with the maximum expansion rate inside voids formed in the corresponding open cosmological model with Ω m=0.87±0.03, whereas the actual value of the Hubble constant implies the age of the Universe that is compatible with the Planck LambdaCDM cosmology. The new dark-matter-dominated model with redshift remapping provides excellent fits to all data and eliminates recently reported tensions between the Planck LambdaCDM cosmology, the local determination of the Hubble constant and the BAO measurements from the Ly α forest of high-redshift quasars.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Milgrom, Mordehai
2009-12-15
A new relativistic formulation of MOND is advanced, involving two metrics as independent degrees of freedom: the MOND metric g{sub {mu}}{sub {nu}}, to which alone matter couples, and an auxiliary metric g-circumflex{sub {mu}}{sub {nu}}. The main idea hinges on the fact that we can form tensors from the difference of the Levi-Civita connections of the two metrics, C{sub {beta}}{sub {gamma}}{sup {alpha}}={gamma}{sub {beta}}{sub {gamma}}{sup {alpha}}-{gamma}-circumflex{sub {beta}}{sub {gamma}}{sup {alpha}}, and these act like gravitational accelerations. In the context of MOND, we can form dimensionless 'acceleration' scalars and functions thereof (containing only first derivatives) from contractions of a{sub 0}{sup -1}C{sub {beta}}{sub {gamma}}{sup {alpha}}.more » I look at a subclass of bimetric MOND theories governed by the action I=-(16{pi}G){sup -1}{integral}[{beta}g{sup 1/2}R+{alpha}g-circumflex{sup 1/2}R-circumflex-2(gg-circumflex){sup 1/4}f({kappa})a{sub 0}{sup 2} M({upsilon}-tilde/a{sub 0}{sup 2})]d{sup 4}x+I{sub M}(g{sub {mu}}{sub {nu}},{psi}{sub i})+I-circumflex{sub M}(g-circumflex{sub {mu}}{sub {nu}},{chi}{sub i}), with {upsilon}-tilde as a scalar quadratic in the C{sub {beta}}{sub {gamma}}{sup {alpha}}, {kappa}=(g/g-circumflex){sup 1/4}, I{sub M} as the matter action, and allow for the existence of twin matter that couples to g-circumflex{sub {mu}}{sub {nu}} alone. Thus, gravity is modified not by modifying the elasticity of the space-time in which matter lives, but by the interaction between that space-time and the auxiliary one. In particular, I concentrate on the interesting and simple choice {upsilon}-tilde{proportional_to}g{sup {mu}}{sup {nu}}(C{sub {mu}}{sub {lambda}}{sup {gamma}}C{sub {nu}}{sub {gamma}}{sup {lambda}}-C{sub {mu}}{sub {nu}}{sup {gamma}}C{sub {lambda}}{sub {gamma}}{sup {lambda}}). This theory introduces only one new constant, a{sub 0}; it tends simply to general relativity (GR) in the limit a{sub 0}{yields}0 and to a phenomenologically valid MOND theory in the nonrelativistic limit. The theory naturally gives MOND and 'dark energy' effects from the same term in the action, both controlled by the MOND constant a{sub 0}. In regards to gravitational lensing by nonrelativistic systems-a holy grail for relativistic MOND theories-the theory predicts that the same potential that controls massive-particle motion also dictates lensing in the same way as in GR: Lensing and massive-particle probing of galactic fields will require the same 'halo' of dark matter to explain the departure of the present theory from GR. This last result can be modified with other choices of {upsilon}-tilde, but lensing is still enhanced and MOND-like, with an effective logarithmic potential.« less
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2013-11-29
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Lin, Jyh-Miin; Patterson, Andrew J; Chang, Hing-Chiu; Gillard, Jonathan H; Graves, Martin J
2015-10-01
To propose a new reduced field-of-view (rFOV) strategy for iterative reconstructions in a clinical environment. Iterative reconstructions can incorporate regularization terms to improve the image quality of periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) MRI. However, the large amount of calculations required for full FOV iterative reconstructions has posed a huge computational challenge for clinical usage. By subdividing the entire problem into smaller rFOVs, the iterative reconstruction can be accelerated on a desktop with a single graphic processing unit (GPU). This rFOV strategy divides the iterative reconstruction into blocks, based on the block-diagonal dominant structure. A near real-time reconstruction system was developed for the clinical MR unit, and parallel computing was implemented using the object-oriented model. In addition, the Toeplitz method was implemented on the GPU to reduce the time required for full interpolation. Using the data acquired from the PROPELLER MRI, the reconstructed images were then saved in the digital imaging and communications in medicine format. The proposed rFOV reconstruction reduced the gridding time by 97%, as the total iteration time was 3 s even with multiple processes running. A phantom study showed that the structure similarity index for rFOV reconstruction was statistically superior to conventional density compensation (p < 0.001). In vivo study validated the increased signal-to-noise ratio, which is over four times higher than with density compensation. Image sharpness index was improved using the regularized reconstruction implemented. The rFOV strategy permits near real-time iterative reconstruction to improve the image quality of PROPELLER images. Substantial improvements in image quality metrics were validated in the experiments. The concept of rFOV reconstruction may potentially be applied to other kinds of iterative reconstructions for shortened reconstruction duration.
Gumerov, Nail A; Duraiswami, Ramani
2009-01-01
The development of a fast multipole method (FMM) accelerated iterative solution of the boundary element method (BEM) for the Helmholtz equations in three dimensions is described. The FMM for the Helmholtz equation is significantly different for problems with low and high kD (where k is the wavenumber and D the domain size), and for large problems the method must be switched between levels of the hierarchy. The BEM requires several approximate computations (numerical quadrature, approximations of the boundary shapes using elements), and these errors must be balanced against approximations introduced by the FMM and the convergence criterion for iterative solution. These different errors must all be chosen in a way that, on the one hand, excess work is not done and, on the other, that the error achieved by the overall computation is acceptable. Details of translation operators for low and high kD, choice of representations, and BEM quadrature schemes, all consistent with these approximations, are described. A novel preconditioner using a low accuracy FMM accelerated solver as a right preconditioner is also described. Results of the developed solvers for large boundary value problems with 0.0001 less, similarkD less, similar500 are presented and shown to perform close to theoretical expectations.
Takeuchi, Toshifumi; Ishidoh, Tomomi; Iijima, Hiroshi; Kuriyama, Isoko; Shimazaki, Noriko; Koiwai, Osamu; Kuramochi, Kouji; Kobayashi, Susumu; Sugawara, Fumio; Sakaguchi, Kengo; Yoshida, Hiromi; Mizushina, Yoshiyuki
2006-03-01
We previously reported that phenolic compounds, petasiphenol and curcumin (diferuloylmethane), were a selective inhibitor of DNA polymerase lambda (pol lambda) in vitro. The purpose of this study was to investigate the molecular structural relationship of curcumin and 13 chemically synthesized derivatives of curcumin. The inhibitory effect on pol lambda (full-length, i.e. intact pol lambda including the BRCA1 C- terminal [BRCT] domain) by some derivatives was stronger than that by curcumin, and monoacetylcurcumin (compound 13) was the strongest pol lambda inhibitor of all the compounds tested, achieving 50% inhibition at a concentration of 3.9 microm. The compound did not influence the activities of replicative pols such as alpha, delta, and epsilon. It had no effect on pol beta activity either, although the three-dimensional structure of pol beta is thought to be highly similar to that of pol lambda. Compound 13 did not inhibit the activity of the C-terminal catalytic domain of pol lambda including the pol beta-like core, in which the BRCT motif was deleted from its N-terminal region. MALDI-TOF MS analysis demonstrated that compound 13 bound selectively to the N-terminal domain of pol lambda, but did not bind to the C-terminal region. Based on these results, the pol lambda-inhibitory mechanism of compound 13 is discussed.
Static RAM data recorder for flight tests
NASA Astrophysics Data System (ADS)
Stoner, D. C.; Eklund, T. F. F.
A static random access memory (RAM) data recorder has been developed to recover strain and acceleration data during development tests of high-speed earth penetrating vehicles. Bilevel inputs are also available for continuity measurements. An iteration of this system was modified for use on water entry evaluations.
NOTE: Acceleration of Monte Carlo-based scatter compensation for cardiac SPECT
NASA Astrophysics Data System (ADS)
Sohlberg, A.; Watabe, H.; Iida, H.
2008-07-01
Single proton emission computed tomography (SPECT) images are degraded by photon scatter making scatter compensation essential for accurate reconstruction. Reconstruction-based scatter compensation with Monte Carlo (MC) modelling of scatter shows promise for accurate scatter correction, but it is normally hampered by long computation times. The aim of this work was to accelerate the MC-based scatter compensation using coarse grid and intermittent scatter modelling. The acceleration methods were compared to un-accelerated implementation using MC-simulated projection data of the mathematical cardiac torso (MCAT) phantom modelling 99mTc uptake and clinical myocardial perfusion studies. The results showed that when combined the acceleration methods reduced the reconstruction time for 10 ordered subset expectation maximization (OS-EM) iterations from 56 to 11 min without a significant reduction in image quality indicating that the coarse grid and intermittent scatter modelling are suitable for MC-based scatter compensation in cardiac SPECT.
Lee, Won Sok; Singh, Gurmukh
2018-07-01
Quantitative evaluation of serum free light chains is recommended for the work up of monoclonal gammopathies. Immunoglobulin light chains are generally produced in excess of heavy chains. In patients with monoclonal gammopathy, κ/λ ratio is abnormal less frequently with lambda chain lesions. This study was undertaken to ascertain if the levels of overproduction of the two light chain types and their detection rates are different in patients with neoplastic monoclonal gammopathies. Results of serum protein electrophoresis (SPEP), serum protein immunofixation electrophoresis (SIFE), urine protein electrophoresis (UPEP), urine protein immunofixation electrophoresis (UIFE), and serum free light chain assay (SFLCA) in patients with monoclonal gammopathies were examined retrospectively. The κ/λ ratios were appropriately abnormal more often in kappa chain lesions. Ratios of κ/λ were normal in about 25% of patients with lambda chain lesions in whom free homogenous lambda light chains were detectable in urine. An illustrative case suggests underproduction of free lambda light chains, in some instances. The lower prevalence of lambda dominant κ/λ ratio in lesions with lambda light chains is estimated to be due to relative under-detection of lambda dominant κ/λ ratio in about 25% of the patients and because lambda chains are not produced in as much excess of heavy chains as are kappa chains, in about 5% of the patients. The results question the medical necessity and clinical usefulness of the serum free light chain assay. UPEP/UIFE is under-utilized.
A search for spectroscopic binaries among the runaway O type stars
NASA Technical Reports Server (NTRS)
Stone, R. C.
1982-01-01
Numerous radial velocity measurements of medium dispersion were made for the 10 brighter stars given in Stone's list of very probable O type runaways. All plates were measured with the KPNO PDS microdensitometer, and a new iterative reductional analysis was used to derive plate velocities, which are estimated to be 1.6 times more accurate internally than those found by using the traditional method. Of thse stars, psi Per, alpha Cam, HD 188209, and 26 Cep are identified as probable velocity variables, while 9 Sge, lambda Cep, and HD 218915 are classed as possible variables. If the source of this variability is Keplerian rather than atmospheric, which cannot be established unequivocally from the observations of this paper, psi Per could be a spectroscopic binary with a black hole companion, and at least 1.2 solar mass. The detection of runaway binary systems from radial velocity measurements is discussed.
Nguyen, Van-Giang; Lee, Soo-Jin
2016-07-01
Iterative reconstruction from Compton scattered data is known to be computationally more challenging than that from conventional line-projection based emission data in that the gamma rays that undergo Compton scattering are modeled as conic projections rather than line projections. In conventional tomographic reconstruction, to parallelize the projection and backprojection operations using the graphics processing unit (GPU), approximated methods that use an unmatched pair of ray-tracing forward projector and voxel-driven backprojector have been widely used. In this work, we propose a new GPU-accelerated method for Compton camera reconstruction which is more accurate by using exactly matched pair of projector and backprojector. To calculate conic forward projection, we first sample the cone surface into conic rays and accumulate the intersecting chord lengths of the conic rays passing through voxels using a fast ray-tracing method (RTM). For conic backprojection, to obtain the true adjoint of the conic forward projection, while retaining the computational efficiency of the GPU, we use a voxel-driven RTM which is essentially the same as the standard RTM used for the conic forward projector. Our simulation results show that, while the new method is about 3 times slower than the approximated method, it is still about 16 times faster than the CPU-based method without any loss of accuracy. The net conclusion is that our proposed method is guaranteed to retain the reconstruction accuracy regardless of the number of iterations by providing a perfectly matched projector-backprojector pair, which makes iterative reconstruction methods for Compton imaging faster and more accurate. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
A highly parallel multigrid-like method for the solution of the Euler equations
NASA Technical Reports Server (NTRS)
Tuminaro, Ray S.
1989-01-01
We consider a highly parallel multigrid-like method for the solution of the two dimensional steady Euler equations. The new method, introduced as filtering multigrid, is similar to a standard multigrid scheme in that convergence on the finest grid is accelerated by iterations on coarser grids. In the filtering method, however, additional fine grid subproblems are processed concurrently with coarse grid computations to further accelerate convergence. These additional problems are obtained by splitting the residual into a smooth and an oscillatory component. The smooth component is then used to form a coarse grid problem (similar to standard multigrid) while the oscillatory component is used for a fine grid subproblem. The primary advantage in the filtering approach is that fewer iterations are required and that most of the additional work per iteration can be performed in parallel with the standard coarse grid computations. We generalize the filtering algorithm to a version suitable for nonlinear problems. We emphasize that this generalization is conceptually straight-forward and relatively easy to implement. In particular, no explicit linearization (e.g., formation of Jacobians) needs to be performed (similar to the FAS multigrid approach). We illustrate the nonlinear version by applying it to the Euler equations, and presenting numerical results. Finally, a performance evaluation is made based on execution time models and convergence information obtained from numerical experiments.
Joint Launch + One Year Science Review of USML-1 and USMP-1 with the Microgravity Measurement Group
NASA Technical Reports Server (NTRS)
Ramachandran, N. (Editor); Frazier, Donald. O. (Editor); Lehoczky, Sandor L. (Editor); Baugher, Charles R. (Editor)
1994-01-01
This document summarizes from the various investigations their comprehensive results and highlights, and also serves as a combined mission report for the first United States Microgravity Laboratory (USML-1) amd the United States Microgravity Payload (USMP-1). USML-1 included 31 investigations in fluid dynamics, crystal growth, combustion, biotechnology, and technology demonstrations supported by 11 facilities. On the USMP-1 mission, both the MEPHISTO and Lambda Point experiments exceeded by over 100 percent their planned science objectives. The mission was also the first time that acceleration data were down-linked and analyzed in real time.
Martin, Guenter; Schmidt, Hagen; Wall, Bert
2004-07-01
The present paper describes single-phase unidirectional transducers (SPUDT) cells with all fingers wider than lambda/8 while maintaining the unidirectional effect. The first solution is related to a SPUDT consisting of lambda/4 and lambda/2 wide fingers arranged in two tracks. Each track has no significant unidirectional effect. Both tracks form a waveguide, and the waveguide coupling generates the interaction of the tracks. As a result of that interaction, a unidirectional effect arises as verified by experiment. This transducer type is called double-track (DT) SPUDT. A second solution is suggested that includes, in contrast to distributed acoustic reflection transducer (DART), electrode width control (EWC), and Hunsinger cells, SPUDT cell fingers with one and the same width only. Cell types with lambda/6, lambda/5, and lambda/3 wide fingers called uniform width electrode (UWE) cells are considered. One of these cell types, including exclusively lambda/5 wide fingers, is experimentally investigated and a unidirectional effect is found. Moreover, a filter example using the lambda/5 cell type has been designed for reducing SPUDT reflections. The echo suppression expected could be verified experimentally. No waveguide coupling is required for this cell type.
Recombination between bacteriophage lambda and plasmid pBR322 in Escherichia coli.
Pogue-Geile, K L; Dassarma, S; King, S R; Jaskunas, S R
1980-01-01
Recombinant lambda phages were isolated that resulted from recombination between the lambda genome and plasmid pBR322 in Escherichia coli, even though these deoxyribonucleic acids (DNAs) did not share extensive regions of homology. The characterization of these recombinant DNAs by heteroduplex analysis and restriction endonucleases is described. All but one of the recombinants appeared to have resulted from reciprocal recombination between a site on lambda DNA and a site on the plasmid. In general, there were two classes of recombinants. One class appeared to have resulted from recombination at the phage attachment site that probably resulted from lambda integration into secondary attachment sites on the plasmid. Seven different secondary attachment sites on pBR322 were found. The other class resulted from plasmid integration at other sites that were widely scattered on the lambda genome. For this second class of recombinants, more than one site on the plasmid could recombine with lambda DNA. Thus, the recombination did not appear to be site specific with respect to lambda or the plasmid. Possible mechanisms for generating these recombinants are discussed. Images PMID:6247334
Development of the negative ion beams relevant to ITER and JT-60SA at Japan Atomic Energy Agency.
Hanada, M; Kojima, A; Tobari, H; Nishikiori, R; Hiratsuka, J; Kashiwagi, M; Umeda, N; Yoshida, M; Ichikawa, M; Watanabe, K; Yamano, Y; Grisham, L R
2016-02-01
In order to realize negative ion sources and accelerators to be applicable to International Thermonuclear Experimental Reactor and JT-60 Super Advanced, a large cesium (Cs)-seeded negative ion source and a multi-aperture and multi-stage electric acceleration have been developed at Japan Atomic Energy Agency (JAEA). Long pulse production and acceleration of the negative ion beams have been independently carried out. The long pulse production of the high current beams has achieved 100 s at the beam current of 15 A by modifying the JT-60 negative ion source. The pulse duration time is increased three times longer than that before the modification. As for the acceleration, a pulse duration time has been also extended two orders of magnitudes from 0.4 s to 60 s. The developments of the negative ion source and acceleration at JAEA are well in progress towards the realization of the negative ion sources and accelerators for fusion applications.
Gyrokinetic theory of turbulent acceleration and momentum conservation in tokamak plasmas
NASA Astrophysics Data System (ADS)
Lu, WANG; Shuitao, PENG; P, H. DIAMOND
2018-07-01
Understanding the generation of intrinsic rotation in tokamak plasmas is crucial for future fusion reactors such as ITER. We proposed a new mechanism named turbulent acceleration for the origin of the intrinsic parallel rotation based on gyrokinetic theory. The turbulent acceleration acts as a local source or sink of parallel rotation, i.e., volume force, which is different from the divergence of residual stress, i.e., surface force. However, the order of magnitude of turbulent acceleration can be comparable to that of the divergence of residual stress for electrostatic ion temperature gradient (ITG) turbulence. A possible theoretical explanation for the experimental observation of electron cyclotron heating induced decrease of co-current rotation was also proposed via comparison between the turbulent acceleration driven by ITG turbulence and that driven by collisionless trapped electron mode turbulence. We also extended this theory to electromagnetic ITG turbulence and investigated the electromagnetic effects on intrinsic parallel rotation drive. Finally, we demonstrated that the presence of turbulent acceleration does not conflict with momentum conservation.
The risk of renal disease is increased in lambda myeloma with bone marrow amyloid deposits.
Kozlowski, Piotr; Montgomery, Scott; Befekadu, Rahel; Hahn-Strömberg, Victoria
2017-01-01
Light chain amyloidosis (AL) is a rare deposition disease and is present in 10-15% of patients with myeloma (MM). In contrast to symptomatic AL in MM, presence of bone marrow (BM) amyloid deposits (AD) in MM is not connected to kidney damage. Renal AD but not BM-AD occur mostly in MM with lambda paraprotein (lambda MM). We investigated amyloid presence in BM clots taken at diagnosis in 84 patients with symptomatic MM and compared disease characteristics in MM with kappa paraprotein (kappa MM)/lambda MM with and without BM-AD. Lambda MM with BM-AD was compared with kappa MM without BM-AD, kappa MM with BM-AD, and lambda MM without BM-AD: lambda MM with BM-AD patients had a significantly higher mean creatinine level (4.23 mg/dL vs 1.69, 1.14, and 1.28 mg/dL, respectively) and a higher proportion presented with severe kidney failure (6/11 [55%] vs 6/32 [19%], 1/22 [5%], and 3/19 [16%], respectively). Proteinuria was more common in lambda MM with BM-AD patients compared with kappa MM without BM-AD patients (8/11 [73%] vs 5/32 [16%], respectively). Kidney damage was more common in lambda MM with BM-AD indicating presence of renal AD.
Chen, Chengyu; Liu, Ying; Shi, Xueyan; Desneux, Nicolas; Han, Peng; Gao, Xiwu
2017-01-01
Quercetin as one of the key plant secondary metabolite flavonol is ubiquitous in terrestrial plants. In this study, the decrease in sensitivity to lambda-cyhalothrin was observed in quercetin-fed Helicoverpa armigera larvae. In order to figure out the mechanisms underlying the decreased sensitivity of H. armigera larvae to lambda-cyhalothrin by quercetin induction, the changes in carboxylesterase activity and in-vitro hydrolytic metabolic capacity to lambda-cyhalothrin were examined. The LC50 value of quercetin-fed H. armigera larvae to lambda-cyhalothrin showed 2.41-fold higher than that of the control. S, S, S-Tributyl phosphorotrithioate (DEF) treatment showed a synergism effect on lambda-cyhalothrin toxicity to quercetin-fed H. armigera. Moreover, the activity of carboxylesterase was significantly higher in quercetin-fed H. armigera larvae after fed on quercetin for 48 h. The in-vitro hydrolytic metabolic capacity to lambda-cyhalothrin in quercetin-fed H. armigera larvae midgut was 289.82 nmol 3-PBA/mg protein/min, which is significant higher than that in the control group (149.60 nmol 3-PBA/mg protein/min). The elevated CarE enzyme activity and corresponding increased hydrolytic metabolic capacity to lambda-cyhalothrin in quercetin-fed H. armigera contributed to the enhanced tolerance to lambda-cyhalothrin.
Chen, Chengyu; Liu, Ying; Desneux, Nicolas; Han, Peng; Gao, Xiwu
2017-01-01
Quercetin as one of the key plant secondary metabolite flavonol is ubiquitous in terrestrial plants. In this study, the decrease in sensitivity to lambda-cyhalothrin was observed in quercetin-fed Helicoverpa armigera larvae. In order to figure out the mechanisms underlying the decreased sensitivity of H. armigera larvae to lambda-cyhalothrin by quercetin induction, the changes in carboxylesterase activity and in-vitro hydrolytic metabolic capacity to lambda-cyhalothrin were examined. The LC50 value of quercetin-fed H. armigera larvae to lambda-cyhalothrin showed 2.41-fold higher than that of the control. S, S, S-Tributyl phosphorotrithioate (DEF) treatment showed a synergism effect on lambda-cyhalothrin toxicity to quercetin-fed H. armigera. Moreover, the activity of carboxylesterase was significantly higher in quercetin-fed H. armigera larvae after fed on quercetin for 48 h. The in-vitro hydrolytic metabolic capacity to lambda-cyhalothrin in quercetin-fed H. armigera larvae midgut was 289.82 nmol 3-PBA/mg protein/min, which is significant higher than that in the control group (149.60 nmol 3-PBA/mg protein/min). The elevated CarE enzyme activity and corresponding increased hydrolytic metabolic capacity to lambda-cyhalothrin in quercetin-fed H. armigera contributed to the enhanced tolerance to lambda-cyhalothrin. PMID:28817718
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lu Bingnan; Zhao Enguang; Center of Theoretical Nuclear Physics, National Laboratory of Heavy Ion Accelerator, Lanzhou 730000
2011-07-15
The shapes of light normal nuclei and {Lambda} hypernuclei are investigated in the ({beta},{gamma}) deformation plane by using a newly developed constrained relativistic mean field (RMF) model. As examples, the results of some C, Mg, and Si nuclei are presented and discussed in details. We found that for normal nuclei the present RMF calculations and previous Skyrme-Hartree-Fock models predict similar trends of the shape evolution with the neutron number increasing. But some quantitative aspects from these two approaches, such as the depth of the minimum and the softness in the {gamma} direction, differ a lot for several nuclei. For {Lambda}more » hypernuclei, in most cases, the addition of a {Lambda} hyperon alters slightly the location of the ground state minimum toward the direction of smaller {beta} and softer {gamma} in the potential energy surface E{approx}({beta},{gamma}). There are three exceptions, namely, {sub {Lambda}}{sup 13}C, {sub {Lambda}}{sup 23}C, and {sub {Lambda}}{sup 31}Si in which the polarization effect of the additional {Lambda} is so strong that the shapes of these three hypernuclei are drastically different from their corresponding core nuclei.« less
Lee, Won Sok; Singh, Gurmukh
2018-01-01
Background Quantitative evaluation of serum free light chains is recommended for the work up of monoclonal gammopathies. Immunoglobulin light chains are generally produced in excess of heavy chains. In patients with monoclonal gammopathy, κ/λ ratio is abnormal less frequently with lambda chain lesions. This study was undertaken to ascertain if the levels of overproduction of the two light chain types and their detection rates are different in patients with neoplastic monoclonal gammopathies. Methods Results of serum protein electrophoresis (SPEP), serum protein immunofixation electrophoresis (SIFE), urine protein electrophoresis (UPEP), urine protein immunofixation electrophoresis (UIFE), and serum free light chain assay (SFLCA) in patients with monoclonal gammopathies were examined retrospectively. Results The κ/λ ratios were appropriately abnormal more often in kappa chain lesions. Ratios of κ/λ were normal in about 25% of patients with lambda chain lesions in whom free homogenous lambda light chains were detectable in urine. An illustrative case suggests underproduction of free lambda light chains, in some instances. Conclusions The lower prevalence of lambda dominant κ/λ ratio in lesions with lambda light chains is estimated to be due to relative under-detection of lambda dominant κ/λ ratio in about 25% of the patients and because lambda chains are not produced in as much excess of heavy chains as are kappa chains, in about 5% of the patients. The results question the medical necessity and clinical usefulness of the serum free light chain assay. UPEP/UIFE is under-utilized. PMID:29904440
Antitumor activity of type I and type III interferons in BNL hepatoma model.
Abushahba, Walid; Balan, Murugabaskar; Castaneda, Ismael; Yuan, Yao; Reuhl, Kenneth; Raveche, Elizabeth; de la Torre, Andrew; Lasfar, Ahmed; Kotenko, Sergei V
2010-07-01
Hepatocellular carcinoma (HCC) occurs most commonly secondary to cirrhosis due to chronic hepatitis C or B virus (HCV/HBV) infections. Type I interferon (IFN-alpha) treatment of chronic HCV/HBV infections reduces the incidence of HCC in cirrhotic patients. However, IFN-alpha toxicity limits its tolerability and efficacy highlighting a need for better therapeutic treatments. A recently discovered type III IFN (IFN-lambda) has been shown to possess antiviral properties against HCV and HBV in vitro. In phase I clinical trials, IFN-lambda treatment did not cause significant adverse reactions. Using a gene therapy approach, we compared the antitumor properties of IFN-alpha and IFN-lambda in a transplantable hepatoma model of HCC. BALB/c mice were inoculated with syngeneic BNL hepatoma cells, or BNL cells expressing IFN-lambda (BNL.IFN-lambda cells) or IFN-alpha (BNL.IFN-alpha cells). Despite the lack of antiproliferative activity of IFNs on BNL cells, both BNL.IFN-lambda and BNL.IFN-alpha cells displayed retarded growth kinetics in vivo. Depletion of NK cells from splenocytes inhibited splenocyte-mediated cytotoxicity, demonstrating that NK cells play a role in IFN-induced antitumor responses. However, isolated NK cells did not respond directly to IFN-lambda. There was also a marked NK cell infiltration in IFN-lambda producing tumors. In addition, IFN-lambda and, to a lesser extent, IFN-alpha enhanced immunocytotoxicity of splenocytes primed with irradiated BNL cells. Splenocyte cytotoxicity against BNL cells was dependent on IL-12 and IFN-gamma, and mediated by dendritic cells. In contrast to NK cells, isolated from spleen CD11c+ and mPDCA+ dendritic cells responded directly to IFN-lambda. The antitumor activities of IFN-lambda against hepatoma, in combination with HCV and HBV antiviral activities warrant further investigation into the clinical use of IFN-lambda to prevent HCC in HCV/HBV-infected cirrhotic patients, as well as to treat liver cancer.
Foster, Graham R; Chayama, Kazuaki; Chuang, Wan-Long; Fainboim, Hugo; Farkkila, Martti; Gadano, Adrian; Gaeta, Giovanni B; Hézode, Christophe; Inada, Yukiko; Heo, Jeong; Kumada, Hiromitsu; Lu, Sheng-Nan; Marcellin, Patrick; Moreno, Christophe; Roberts, Stuart K; Strasser, Simone I; Thompson, Alexander J; Toyota, Joji; Paik, Seung Woon; Vierling, John M; Zignego, Anna L; Cohen, David; McPhee, Fiona; Wind-Rotolo, Megan; Srinivasan, Subasree; Hruska, Matthew; Myler, Heather; Portsmouth, Simon D
2016-01-01
Peginterferon Lambda was being developed as an alternative to alfa interferon for the treatment of chronic hepatitis C virus (HCV) infection. We compared peginterferon Lambda-1a plus ribavirin (Lambda/RBV) and Lambda/RBV plus daclatasvir (DCV; pangenotypic NS5A inhibitor) with peginterferon alfa-2a plus RBV (alfa/RBV) in treatment-naive patients with HCV genotype 2 or 3 infection. In this multicenter, double-blind, phase 3 randomized controlled trial, patients were assigned 2:2:1 to receive 24 weeks of Lambda/RBV, 12 weeks of Lambda/RBV + DCV, or 24 weeks of alfa/RBV. The primary outcome measure was sustained virologic response at post-treatment Week 12 (SVR12). Overall, 874 patients were treated: Lambda/RBV, n = 353; Lambda/RBV + DCV, n = 349; alfa/RBV, n = 172. Patients were 65 % white and 33 % Asian, 57 % male, with a mean age of 47 years; 52 % were infected with genotype 2 (6 % cirrhotic) and 48 % with genotype 3 (9 % cirrhotic). In the Lambda/RBV + DCV group, 83 % (95 % confidence interval [CI] 78.5, 86.5) achieved SVR12 (90 % genotype 2, 75 % genotype 3) whereas SVR12 was achieved by 68 % (95 % CI 63.1, 72.9) with Lambda/RBV (72 % genotype 2, 64 % genotype 3) and 73 % (95 % CI 66.6, 79.9) with peginterferon alfa/RBV (74 % genotype 2, 73 % genotype 3). Lambda/RBV + DCV was associated with lower incidences of flu-like symptoms, hematological abnormalities, and discontinuations due to adverse events compared with alfa/RBV. The 12-week regimen of Lambda/RBV + DCV was superior to peginterferon alfa/RBV in the combined population of treatment-naive patients with genotype 2 or 3 infection, with an improved tolerability and safety profile compared with alfa/RBV.
Dynamic processes in Be star atmospheres. 2: He I 2P-nD line formation in lambda Eridani (outburst)
NASA Technical Reports Server (NTRS)
Smith, Myron A.; Hubeny, Ivan; Lanz, Thierry; Meylan, Thomas
1994-01-01
The He I lambda 6678 line of early Be stars generally shows violet (V) and red (R) emission whenever hydrogen alpha emission is present, but its use as a diagnostic has been handicapped by a poor understanding of the processes that drive it into emission. In an attempt to address this problem we obtained three series of eschelle spectra of the first two members of the singlet and triplet 2P-nD series of lambda Eri (B2e) during 1992 November 3-5 at Kitt Peak. During these observations lambda 6678 showed substantial emission variability in both the wings and central profile, providing an opportunity to compare its behavior with that of the lambda 4922, lambda 5876, and lambda 4471 lines. We found that the responses of the lines were different in several respects. Whereas the emissions in the V wings of all four lines scaled together, the R wing of the lambda 4922 line invariably responded with increased absorption whenever the R wing of lambda 6678 line showed increased emission. These same trends occurred within the central photospheric profiles. The R-wing behavior shows that much, but not all of the emission in lambda 6678 is caused by matter projected against the stellar disk. The excitation temperatures of the neighboring 2(sup 1) P transitions, lambda 6678 and lambda 4922 must be greater than and less than the photospheric continuum temperature, respectively. We have investigated departures from local thermodynamic equilibrium (LTE) for the He I spectrum in a variety of ad hoc, perturbed model atmospheres. We have found only one way to cause the source function of lambda 6678 to increase so strongly, namely, by increasing the atmospheric temperature in the line formation region to 30,000 - 40,000 K. This effect was discovered by Auer and Mihalas for O3-O4 atmospheric models, but it has not been applied to active B stars. Our models suggest that lambda 6678 emission in Be stars can be used as a sensitive monitor of localized hot spots on these stars' surfaces. The energies involved in heating the active portions of the atmosphere are too high to be produced by gravitational infall. This leaves magnetically induced flares among the few known processes on the surfaces of stars capable of sustaining this energy level.
Shen, Xiao-Yan; Liu, Jing; Dai, Kang; Shen, Yi-Fan
2010-02-01
Pure potassium vapor or K-H2 mixture was irradiated in a glass fluorescence cell with pulses of 710 nm radiation from an OPO laser, populating K2 (1lambda(g)) state by two-photon absorption. Cross sections for 1lambda(g)-3lambda(g) transfer in K2 were determined using methods of molecular fluorescence. During the experiments with pure K vapor, the cell temperature was varied between 553 and 603 K. The K number density was determined spectroscopically by the white-light absorption measurement in the blue wing of the self-broadened resonance D2 line. The resulting fluorescence included a direct component emitted in the decay of the optically excitation and a sensitized component arising from the collisionally populated state. The decay signal of time-resolved fluorescence from1lambda(g) -->1 1sigma(u)+ transition was monitored. It was seen that just after the laser pulse the fluorescence of the photoexcited level decreased exponentially. The effective lifetimes of the 1lambda(g) state can be resolved. The plot of reciprocal of effective lifetimes of the 1lambda(g) state against K densities yielded the slope that indicated the total cross section for deactivation and the intercept that provided the radiative lifetime of the state. The radiative lifetime (20 +/- 2) ns was obtained. The cross section for deactivation of the K2(1lambda(g)) molecules by collisions with K is (2.5 +/- 0.3) x 10(-14) cm2. The time-resolved intensities of the K23lambda(g) --> 1 3sigma(u)+ (484 nm) line were measured. The radiative lifetime (16.0 +/- 3.2) ns and the total cross section (2.5 +/- 0.6) x 10(-14) cm2 for deactivation of the K2 (3lambda(g)) state can also be determined through the analogous procedure. The time-integrated intensities of 1lambda(g) --> 1 1sigma(u)+ and 3lambda(g) --> 1 3sigma(u)+ transitions were measured. The cross section (1.1 +/- 0.3) x10(-14) cm2 was obtained for K2 (1lambda(g))+ K --> K2 (3lambda(g)) + K collisions. During the experiments with K-H2 mixture, the cell temperature was kept constant at 553 K. The H2 pressure was varied between 40 and 400 Pa. The effects of K2-K collisions could not be neglected. These effects were subtracted out using the results of the pure K experiments. The cross section (2.7 +/- 1.1) x 10(-15) cm2 was obtained for K2 (1lambda(g)) + H2 --> K2 (3lambda(g))+H2 collisions. The cross section is (6.8 +/- 2.7) x 10(-15) cm2 for K2 (3lambda(g)) + H2 --> states out of K2 (3lambda(g)) + H2 collisions.
Algorithm for ion beam figuring of low-gradient mirrors.
Jiao, Changjun; Li, Shengyi; Xie, Xuhui
2009-07-20
Ion beam figuring technology for low-gradient mirrors is discussed. Ion beam figuring is a noncontact machining technique in which a beam of high-energy ions is directed toward a target workpiece to remove material in a predetermined and controlled fashion. Owing to this noncontact mode of material removal, problems associated with tool wear and edge effects, which are common in conventional contact polishing processes, are avoided. Based on the Bayesian principle, an iterative dwell time algorithm for planar mirrors is deduced from the computer-controlled optical surfacing (CCOS) principle. With the properties of the removal function, the shaping process of low-gradient mirrors can be approximated by the linear model for planar mirrors. With these discussions, the error surface figuring technology for low-gradient mirrors with a linear path is set up. With the near-Gaussian property of the removal function, the figuring process with a spiral path can be described by the conventional linear CCOS principle, and a Bayesian-based iterative algorithm can be used to deconvolute the dwell time. Moreover, the selection criterion of the spiral parameter is given. Ion beam figuring technology with a spiral scan path based on these methods can be used to figure mirrors with non-axis-symmetrical errors. Experiments on SiC chemical vapor deposition planar and Zerodur paraboloid samples are made, and the final surface errors are all below 1/100 lambda.
Developing DIII-D To Prepare For ITER And The Path To Fusion Energy
NASA Astrophysics Data System (ADS)
Buttery, Richard; Hill, David; Solomon, Wayne; Guo, Houyang; DIII-D Team
2017-10-01
DIII-D pursues the advancement of fusion energy through scientific understanding and discovery of solutions. Research targets two key goals. First, to prepare for ITER we must resolve how to use its flexible control tools to rapidly reach Q =10, and develop the scientific basis to interpret results from ITER for fusion projection. Second, we must determine how to sustain a high performance fusion core in steady state conditions, with minimal actuators and a plasma exhaust solution. DIII-D will target these missions with: (i) increased electron heating and balanced torque neutral beams to simulate burning plasma conditions (ii) new 3D coil arrays to resolve control of transients (iii) off axis current drive to study physics in steady state regimes (iv) divertors configurations to promote detachment with low upstream density (v) a reactor relevant wall to qualify materials and resolve physics in reactor-like conditions. With new diagnostics and leading edge simulation, this will position the US for success in ITER and a unique knowledge to accelerate the approach to fusion energy. Supported by the US DOE under DE-FC02-04ER54698.
Cyclic Game Dynamics Driven by Iterated Reasoning
Frey, Seth; Goldstone, Robert L.
2013-01-01
Recent theories from complexity science argue that complex dynamics are ubiquitous in social and economic systems. These claims emerge from the analysis of individually simple agents whose collective behavior is surprisingly complicated. However, economists have argued that iterated reasoning–what you think I think you think–will suppress complex dynamics by stabilizing or accelerating convergence to Nash equilibrium. We report stable and efficient periodic behavior in human groups playing the Mod Game, a multi-player game similar to Rock-Paper-Scissors. The game rewards subjects for thinking exactly one step ahead of others in their group. Groups that play this game exhibit cycles that are inconsistent with any fixed-point solution concept. These cycles are driven by a “hopping” behavior that is consistent with other accounts of iterated reasoning: agents are constrained to about two steps of iterated reasoning and learn an additional one-half step with each session. If higher-order reasoning can be complicit in complex emergent dynamics, then cyclic and chaotic patterns may be endogenous features of real-world social and economic systems. PMID:23441191
A multi-level solution algorithm for steady-state Markov chains
NASA Technical Reports Server (NTRS)
Horton, Graham; Leutenegger, Scott T.
1993-01-01
A new iterative algorithm, the multi-level algorithm, for the numerical solution of steady state Markov chains is presented. The method utilizes a set of recursively coarsened representations of the original system to achieve accelerated convergence. It is motivated by multigrid methods, which are widely used for fast solution of partial differential equations. Initial results of numerical experiments are reported, showing significant reductions in computation time, often an order of magnitude or more, relative to the Gauss-Seidel and optimal SOR algorithms for a variety of test problems. The multi-level method is compared and contrasted with the iterative aggregation-disaggregation algorithm of Takahashi.
ORFEUS spectroscopy of the O BT VI lines in symbiotic stars and the Raman scattering process
NASA Astrophysics Data System (ADS)
Schmid, H. M.; Krautter, J.; Appenzeller, I.; Barnstedt, J.; Dumm, T.; Fromm, A.; Gölz, M.; Grewing, M.; Gringel, W.; Haas, C.; Hopfensitz, W.; Kappelmann, N.; Krämer, G.; Lindenberger, A.; Mandel, H.; Mürset, U.; Schild, H.; Schmutz, W.; Widmann, H.
1999-08-01
We present orfeus spectra of the O vi lambda lambda 1032,1038 emission lines in the symbiotic stars AG Dra, V1016 Cyg, RR Tel, CD-43(deg) 14304, AG Peg and Z And. The O vi emission lines can convert into broad and highly polarized emission lines at lambda 6825 and lambda 7082 in a Raman scattering process by neutral hydrogen. From a comparison of direct and Raman scattered radiation we extract new information on the scattering geometry in symbiotic systems. The nebular O vi emission lines are in all objects redshifted by about +40 km s(-1) . This can be explained as a radiative line transfer effect in a slowly expanding emission region. A comparable redshift is measured in the Raman scattered O vi lines. In AG Peg the O vi emissions show beside a narrow nebular line a broad component from a fast stellar wind outflow. Many interstellar absorption lines of molecular hydrogen are detected, particularly near the O vi lambda 1038 component. With model calculations we investigate their impact on the O vi lines. From the dereddened line fluxes of the direct and Raman scattered O vi lines we derive the scattering efficiency, which is defined as photon flux ratio N_Raman/N_O VI. The efficiencies derived for RR Tel, V1016 Cyg and Z And indicate that about 30% of the released O vi lambda 1032 photons interact with the neutral scattering region. The efficiencies for AG Dra and CD-43(deg14304) are much higher, which may suggest that the O vi nebulosity is embedded in a H(0) -region. The D-type system RR Tel shows strong line profile differences between the direct O vi emission, which is single-peaked, and the Raman scattered emission, which is double-peaked. This indicates that the neutral scattering region in RR Tel ``sees'' different O vi line profiles, implying that the O vi nebulosity is far from spherically symmetric. In a tentative model we suggest for RR Tel an O vi flow pattern where material streams from the cool giant towards the hot component, which further accelerates the gas radially. For the S-type systems AG Dra, CD-43(deg14304) and Z And the line profile differences between the direct and the Raman scattered O vi emissions are less pronounced. This may suggest that the O vi profiles depend less on the emission direction than in the D-type system RR Tel. For AG Peg we detect for the first time the Raman scattered emission at lambda 6825. The Raman line shows a narrow, nebular component as the O vi line, but no equivalent emission to the broad O vi wind component. The higher conversion efficiency for the narrow component indicates that the nebular O vi emission is significantly closer to the cool giant than the hot, mass losing component, and strongly supports previous colliding wind models for this object. Based on observations taken during the orfeus-spas i and orfeus-spas ii space shuttle missions, and ground based data collected at the ESO 2.2m and 3.6m telescopes at La Silla, Chile, and the 4.2m William Herschel Telescope at La Palma, Canary Islands. ESO observations were granted for the programs 52.7-040 and 58.D-0866.
Estimation of the dust production rate from the tungsten armour after repetitive ELM-like heat loads
NASA Astrophysics Data System (ADS)
Pestchanyi, S.; Garkusha, I.; Makhlaj, V.; Landman, I.
2011-12-01
Experimental simulations for the erosion rate of tungsten targets under ITER edge-localized mode (ELM)-like surface heat loads of 0.75 MJ m-2 causing surface melting and of 0.45 MJ m-2 without melting have been performed in the QSPA-Kh50 plasma accelerator. Analytical considerations allow us to conclude that for both energy deposition values the erosion mechanism is solid dust ejection during surface cracking under the action of thermo-stress. Tungsten influx into the ITER containment of NW~5×1018 W per medium size ELM of 0.75 MJ m-2 and 0.25 ms time duration has been estimated. The radiation cooling power of Prad=150-300 MW due to such influx of tungsten is intolerable: it should cool the ITER core to 1 keV within a few seconds.
Iterative feature refinement for accurate undersampled MR image reconstruction
NASA Astrophysics Data System (ADS)
Wang, Shanshan; Liu, Jianbo; Liu, Qiegen; Ying, Leslie; Liu, Xin; Zheng, Hairong; Liang, Dong
2016-05-01
Accelerating MR scan is of great significance for clinical, research and advanced applications, and one main effort to achieve this is the utilization of compressed sensing (CS) theory. Nevertheless, the existing CSMRI approaches still have limitations such as fine structure loss or high computational complexity. This paper proposes a novel iterative feature refinement (IFR) module for accurate MR image reconstruction from undersampled K-space data. Integrating IFR with CSMRI which is equipped with fixed transforms, we develop an IFR-CS method to restore meaningful structures and details that are originally discarded without introducing too much additional complexity. Specifically, the proposed IFR-CS is realized with three iterative steps, namely sparsity-promoting denoising, feature refinement and Tikhonov regularization. Experimental results on both simulated and in vivo MR datasets have shown that the proposed module has a strong capability to capture image details, and that IFR-CS is comparable and even superior to other state-of-the-art reconstruction approaches.
NASA Technical Reports Server (NTRS)
Heinen, Vernon O.; Miranda, Felix A.; Bhasin, Kul B.
1992-01-01
A power transmission measurement technique was used to determine the magnetic penetration depth (lambda) of YBa2Cu3O(7-delta) superconducting thin films on LaAlO3 within the 26.5 to 40.0 GHz frequency range, and at temperatures from 20 to 300 K. Values of lambda ranging from 1100 to 2500 A were obtained at low temperatures. The anisotropy of lambda was determined from measurements of c-axis and a-axis oriented films. An estimate of the intrinsic value of lambda of 90 +/- 30 nm was obtained from the dependence of lambda on film thickness. The advantage of this technique is that it allows lambda to be determined nondestructively.
Measurement of the Branching Ratio Lambda_c+ -> p pi+ pi- (in Spanish)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lopez-Hinojosa, Guillermo; /San Luis Potosi U.
2008-03-01
The confirmation of the Cabibbo-suppressed charm baryon decay mode {Lambda}{sub c}{sup +} {yields} p{pi}{sup +}{pi}{sup -} is reported. All data analyzed are from SELEX, a fixed target experiment at Fermilab that took data during 1996 and 1997, mainly with a 600 GeV/c {Sigma}{sup -} beam. The branching ratio of the Cabibbo-suppressed decay mode {Lambda}{sub c}{sup +} {yields} p{pi}{sup +}{pi}{sup -} relative to the Cabibbo-favored mode {Lambda}{sub c}{sup +} {yields} pK{sup -}{pi}{sup +} is measured to be: {Gamma}({Lambda}{sub c}{sup +} {yields} p{pi}{sup +}{pi}{sup -})/{Gamma}({Lambda}{sub c}{sup +} {yields} pK{sup -}{pi}{sup +}) = 0.103 {+-} 0.022.
Autofluorescence spectroscopy of oral mucosa
NASA Astrophysics Data System (ADS)
Majumdar, S. K.; Uppal, A.; Gupta, P. K.
1998-06-01
We report the results of an in-vitro study on autofluorescence from pathologically characterized normal and malignant squamous tissues from the oral cavity. The study involved biopsy samples from 47 patients with oral cancer of which 11 patients had cancer of tongue, 17 of buccal mucosa and 19 of alveolus. The results of excitation and emission spectroscopy at several wavelengths (280 nm less than or equal to (lambda) exless than or equal to 460 nm; 340 nm less than or equal to (lambda) em less than or equal to 520 nm) showed that at (lambda) ex equals 337 nm and 400 nm the mean value for the spectrally integrated fluorescence intensity [(Sigma) (lambda ) IF((lambda) )] from the normal tissue sites was about a factor of 2 larger than that from the malignant tissue sites. At other excitation wavelengths the difference in (Sigma) (lambda ) IF((lambda) ) was not statistically significant. Similarly, for (lambda) em equals 390 nm and 460 nm, the intensity of the 340 nm band of the excitation spectra from normal tissues was observed to be a factor of 2 larger than that from malignant tissues. Analysis of these results suggests that NADH concentration is higher in normal oral tissues compared to the malignant. This contrasts with our earlier observation of an reduced NADH concentration in normal sites of breast tissues vis a vis malignant sites. For the 337 nm excited emission spectra a 10-variable MVLR score (using (Sigma) (lambda ) IF((lambda) ) and normalized intensities at nine wavelengths as input parameters) provided a sensitivity and specificity of 95.7% and 93.1% over the sample size investigated.
Long-pulse beam acceleration of MeV-class H(-) ion beams for ITER NB accelerator.
Umeda, N; Kashiwagi, M; Taniguchi, M; Tobari, H; Watanabe, K; Dairaku, M; Yamanaka, H; Inoue, T; Kojima, A; Hanada, M
2014-02-01
In order to realize neutral beam systems in International Thermonuclear Experimental Reactor whose target is to produce a 1 MeV, 200 A/m(2) during 3600 s D(-) ion beam, the electrostatic five-stages negative ion accelerator so-called "MeV accelerator" has been developed at Japan Atomic Energy Agency. To extend pulse length, heat load of the acceleration grids was reduced by controlling the ion beam trajectory. Namely, the beam deflection due to the residual magnetic field of filter magnet was suppressed with the newly developed extractor with a 0.5 mm off-set aperture displacement. The new extractor improved the deflection angle from 6 mrad to 1 mrad, resulting in the reduction of direct interception of negative ions from 23% to 15% of the total acceleration power, respectively. As a result, the pulse length of 130 A/m(2), 881 keV H(-) ion beam has been successfully extended from a previous value of 0.4 s to 8.7 s. This is the first long pulse negative ion beam acceleration over 100 MW/m(2).
Abbas, Naeem; Shah, Rizwan Mustafa; Shad, Sarfraz Ali; Iqbal, Naeem; Razaq, Muhammad
2016-05-01
House flies, Musca domestica L., (Diptera: Muscidae), are pests of poultry and have the ability to develop resistance to insecticides. To design a strategy for resistance management, life history traits based on laboratory observations were established for lambda-cyhalothrin-resistant, susceptible and reciprocal crosses of M. domestica strains. Bioassay results showed that the lambda-cyhalothrin-selected strain developed a resistance ratio of 98.34 compared to its susceptible strain. The lambda-cyhalothrin-selected strain had a relative fitness of 0.26 and lower fecundity, hatchability, lower number of next generation larvae, and net reproductive rate compared with its susceptible strain. Mean population growth rates, such as intrinsic rate of population increase, and biotic potential were lower for the lambda-cyhalothrin-selected strain compared to its susceptible strain. Resistance to lambda-cyhalothrin, indoxacarb, and abamectin was unstable while resistance to bifenthrin and methomyl was stable in the lambda-cyhalothrin-selected strain of M. domestica. Development of resistance can cost considerable fitness for the lambda-cyhalothrin-selected strain. The present study provided useful information for making potential management strategies to delay resistance development in M. domestica.
Depolymerized products of lambda-carrageenan as a potent angiogenesis inhibitor.
Chen, Haimin; Yan, Xiaojun; Lin, Jing; Wang, Feng; Xu, Weifeng
2007-08-22
Since angiogenesis is involved in initiating and promoting several diseases such as cancer and cardiovascular events, this study was designed to evaluate the anti-angiogenesis of low-molecular-weight (LMW), highly sulfated lambda-carrageenan oligosaccharides (lambda-CO) obtained by carrageenan depolymerization, by CAM (chick chorioallantoic membrane) model and human umbilical vein endothelial cells (HUVECs). Significant inhibition of vessel growth was observed at 200 microg/pellet. A histochemistry assay also revealed a decrease of capillary plexus and connective tissue in lambda-CO treated samples. lambda-CO inhibited the viability of cells at the high concentration of 1 mg/mL, whereas it affected the cell survival slightly (>95%) at a low concentration (<250 microg/mL), and HUVEC is the most sensitive to lambda-CO among three kinds of cells. Furthermore, the inhibitory action of lambda-CO was also observed in the endothelial cell invasion and migration at relatively low concentration (150-300 microg/mL), through down-regulation of intracellular matrix metalloproteinases (MMP-2) expression on endothelial cells. Taken together, these findings demonstrate that lambda-CO is a potential angiogenesis inhibitor with combined effects of inhibiting invasion, migration, and proliferation.
Piner, Petek; Uner, Nevin
2012-05-01
The aim of this study was to investigate the toxic effects of pyrethroid pesticide lambda-cyhalothrin in the presence of piperonyl butoxide as a modulator in the liver of juvenile Oreochromis niloticus. LC(50) (96h) value of lambda-cyhalothrin was determined as 2.901μg/L for O. niloticus. The fish were exposed to 0.48μg/L (1/6 of the 96-h LC(50)) lambda-cyhalothrin and 10μg/L piperonyl butoxide for 96-h and 15-d. tGSH, GSH, GSSG, Hsp70 and TBARS contents, GPx, GR, GST and caspase-3 enzymes activities were determined. Lambda-cyhalothrin caused increases in tGSH, GSH, TBARS contents, and GST activity. Piperonyl butoxide treatment with lambda-cyhalothrin caused significant increases in tGSH GSH, Hsp70, TBARS contents, and GPx and GST activities while caspase-3 activity was decreased. The results of the present study revealed that lambda-cyhalothrin caused oxidative stress which upregulated GSH and GSH-related enzymes. Piperonyl butoxide increased the oxidative stress potential and apoptotic effects of lambda-cyhalothrin. Copyright © 2012 Elsevier B.V. All rights reserved.
New charged black holes with conformal scalar hair
DOE Office of Scientific and Technical Information (OSTI.GOV)
Anabalon, Andres; Centro de Estudios Cientificos; Maeda, Hideki
A new class of four-dimensional, hairy, stationary solutions of the Einstein-Maxwell-{Lambda} system with a conformally coupled scalar field is obtained. The metric belongs to the Plebanski-Demianski family and hence its static limit has the form of the charged (A)dS C metric. It is shown that, in the static case, a new family of hairy black holes arises. They turn out to be cohomogeneity-two, with horizons that are neither Einstein nor homogenous manifolds. The conical singularities in the C metric can be removed due to the backreaction of the scalar field providing a new kind of regular, radiative spacetime. The scalarmore » field carries a continuous parameter proportional to the usual acceleration present in the C metric. In the zero-acceleration limit, the static solution reduces to the dyonic Bocharova-Bronnikov-Melnikov-Bekenstein solution or the dyonic extension of the Martinez-Troncoso-Zanelli black holes, depending on the value of the cosmological constant.« less
Optical shaping of gas targets for laser–plasma ion sources
Dover, N. P.; Cook, N.; Tresca, O.; ...
2016-02-09
In this paper, we report on the experimental demonstration of a technique to generate steep density gradients in gas-jet targets of interest to laser–plasma ion acceleration. By using an intentional low-energy prepulse, we generated a hydrodynamic blast wave in the gas to shape the target prior to the arrival of an intense COmore » $$_{2}$$($${\\it\\lambda}\\approx 10~{\\rm\\mu}\\text{m}$$) drive pulse. This technique has been recently shown to facilitate the generation of ion beams by shockwave acceleration (Trescaet al.,Phys. Rev. Lett., vol. 115 (9), 2015, 094802). Here, we discuss and introduce a model to understand the generation of these blast waves and discuss in depth the experimental realisation of the technique, supported by hydrodynamics simulations. With appropriate prepulse energy and timing, this blast wave can generate steepened density gradients as short as$$l\\approx 20~{\\rm\\mu}\\text{m}$$($1/e$), opening up new possibilities for laser–plasma studies with near-critical gaseous targets.« less
Determination of $${{\\rm{\\Lambda }}}_{\\overline{{\\rm{MS}}}}$$ at five loops from holographic QCD
Deur, Alexandre; Brodsky, Stanley J.; de Téramond, Guy F.
2017-08-25
Here, the recent determination of themore » $$\\beta$$--function of the QCD running coupling $$\\alpha_{\\overline{MS}}(Q^2)$$ to five-loops, provides a verification of the convergence of a novel method for determining the fundamental QCD parameter $$\\Lambda_s$$ based on the Light-Front Holographic approach to nonperturbative QCD. The new 5-loop analysis, together with improvements in determining the holographic QCD nonperturbative scale parameter $$\\kappa$$ from hadronic spectroscopy, leads to an improved precision of the value of $$\\Lambda_s$$ in the $${\\overline{MS}}$$ scheme close to a factor of two; we find $$\\Lambda^{(3)}_{\\overline{MS}}=0.339\\pm0.019$$ GeV for $$n_{f}=3$$, in excellent agreement with the world average, $$\\Lambda_{\\overline{MS}}^{(3)}=0.332\\pm0.017$$ GeV. Lastly, we also discuss the constraints imposed on the scale dependence of the strong coupling in the nonperturbative domain by superconformal quantum mechanics and its holographic embedding in anti-de Sitter space.« less
IUE and Einstein observations of the LINER galaxy NGC 4579
NASA Technical Reports Server (NTRS)
Reichert, G. A.; Puchnarewicz, E. M.; Mason, K. O.
1990-01-01
Results of International Ultraviolet Explorer (IUE) and Einstein observations of the LINER galaxy NGC 4579 are reported. Spatial profiles of the long wavelength IUE emission show a two component structure, with an unresolved core superimposed on broader underlying emission. The core spectrum shows strong C II lambda 2326 and broad Mg II lambda 2800 emission, and perhaps emission due to blends of Fe II multiplets (2300 to 23600 angstrom). The short wavelength emission is spatially unresolved, and shows C II lambda 1335, C III lambda 1909 broad C IV lambda 1550 emission, and a broad feature at approximately 1360 angstrom which may be due to 0.1 lambda 1356. Contrary to previous reports no evidence for He II lambda 1640 is found in the spectrum. An unresolved x ray source is detected at the location of the nucleus; its spectrum is well fitted by a power law of energy slope alpha approximately -0.5. These results further support the idea that NGC 4579 may contain a dwarf Seyfert nucleus.
Brown, Edward J.; Baldasaro, Paul F.; Dziendziel, Randolph J.
1997-01-01
A filter system to transmit short wavelength radiation and reflect long wavelength radiation for a thermophotovoltaic energy conversion cell comprises an optically transparent substrate segregation layer with at least one coherent wavelength in optical thickness; a dielectric interference filter deposited on one side of the substrate segregation layer, the interference filter being disposed toward the source of radiation, the interference filter including a plurality of alternating layers of high and low optical index materials adapted to change from transmitting to reflecting at a nominal wavelength .lambda..sub.IF approximately equal to the bandgap wavelength .lambda..sub.g of the thermophotovoltaic cell, the interference filter being adapted to transmit incident radiation from about 0.5.lambda..sub.IF to .lambda..sub.IF and reflect from .lambda..sub.IF to about 2.lambda..sub.IF ; and a high mobility plasma filter deposited on the opposite side of the substrate segregation layer, the plasma filter being adapted to start to become reflecting at a wavelength of about 1.5.lambda..sub.IF.
[In vitro anti-angiogenic action of lambda-carrageenan oligosaccharides].
Chen, Hai-Min; Yan, Xiao-Jun; Wang, Feng; Lin, Jing; Xu, Wei-Feng
2007-06-01
This study was designed to evaluate the inhibition effect of lambda-carrageenan oligosaccharides on neovascularization in vitro by chick chorioallantoic membrane (CAM) model and human umbilical vein endothelial cell ( HUVEC). lambda-Carrageenan oligosaccharides caused a dose-dependent decrease of the vascular density of CAM, and adversely affected capillary plexus formation. At a high concentration of 1 mg x mL(-1), this compound inhibited the endothelial cell proliferation, while low concentration of lambda-carrageenan oligosaccharides (< 250 microg x mL(-1)) affected the cell survival slightly (> 95%). Different cytotoxic sensitivity of lambda-carrageenan oligosaccharides in three kinds of cells was observed, of which HUVEC is the most sensitive to this oligosaccharides. The inhibitory action of lambda-carrageenan oligosaccharides on the endothelial cell invasion and migration was also observed at relatively low concentration (150 - 300 microg x mL(-1)) through down-regulation of intracellular matrix metalloproteinases-2 (MMP-2) expression on endothelial cells. Current observations demonstrated that lambda-carrageenan oligosaccharides are potential angiogenesis inhibitor with combined effects of inhibiting invasion, migration and proliferation.
Effect of atmospheric extinction on laser rangefinder performance at 1.54 and 0.6 microns
NASA Technical Reports Server (NTRS)
Hutt, D. L.; Theriault, J.-M.; Larochelle, V.; Bonnier, D.
1992-01-01
Extinction of laser rangefinder (LRF) pulses by the atmosphere depends on the wavelength, weather conditions, and aerosol concentration along the optical path. In the IR, extinction is due to absorption by molecular constituents and scattering and absorption by aerosols. The total atmospheric extinction alpha(lambda) is the sum of the molecular and aerosol contributions, alpha(sub m)(lambda)and Alpha(sub a)(lambda). We present simple expressions for alpha(sub m)(lambda) and alpha(sub a)(lambda) for two LRF sources: Er:glass and CO2 which operate at 1.54 and 10.6 microns, respectively. The expressions are based on accepted models of atmospheric aerosols and molecular extinction and give an estimate of alpha(lambda) as a function of standard meteorological parameters, assuming horizontal beam propagation. Signal-to-noise ratios of LRF returns, measured from a reference target under different weather conditions are compared to predictions based on the estimate of alpha(lambda).
NASA Technical Reports Server (NTRS)
Marshak, Alexander; Knyazikhin, Yuri; Chiu, J. Christine; Wiscombe, Warren J.
2012-01-01
The single scattering albedo omega(sub O lambda) in atmospheric radiative transfer is the ratio of the scattering coefficient to the extinction coefficient. For cloud water droplets both the scattering and absorption coefficients, thus the single scattering albedo, are functions of wavelength lambda and droplet size r. This note shows that for water droplets at weakly absorbing wavelengths, the ratio omega(sub O lambda)(r)/omega(sub O lambda)(r (sub O)) of two single scattering albedo spectra is a linear function of omega(sub O lambda)(r). The slope and intercept of the linear function are wavelength independent and sum to unity. This relationship allows for a representation of any single scattering albedo spectrum omega(sub O lambda)(r) via one known spectrum omega(sub O lambda)(r (sub O)). We provide a simple physical explanation of the discovered relationship. Similar linear relationships were found for the single scattering albedo spectra of non-spherical ice crystals.
Duality symmetry and power-law fading of frustration in a quantum multiconnected superconductor
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sun, S.N.; Ralston, J.P.
1991-03-01
We generalize the Alexander--de Gennes equations to a new system of superconducting-wire networks, allowing for variation of the cross-sectional area of wires. The generalized equations are solved for a square lattice of different cross-sectional-area ratios {lambda} in the {ital x} and {ital y} directions. A symmetry of {lambda}{r arrow}1/{lambda} is related to the Aubry-Andre duality and an obvious geometric property. We find that even a slight geometric asymmetry can soften the fine structure of the magnetic phase boundary considerably. We obtain a power-law dependence on the parameter {lambda} as {lambda}{r arrow}{infinity} and {lambda}{r arrow}0. For a finite-area ratio {lambda}, wemore » speculate that a simple analytic fit incorporating the dual symmetry is close to the exact nonperturbative behavior. The system is also related analytically to a recent study of Hu and Chen, which revealed a power-law behavior for a rectangular lattice.« less
Layout compliance for triple patterning lithography: an iterative approach
NASA Astrophysics Data System (ADS)
Yu, Bei; Garreton, Gilda; Pan, David Z.
2014-10-01
As the semiconductor process further scales down, the industry encounters many lithography-related issues. In the 14nm logic node and beyond, triple patterning lithography (TPL) is one of the most promising techniques for Metal1 layer and possibly Via0 layer. As one of the most challenging problems in TPL, recently layout decomposition efforts have received more attention from both industry and academia. Ideally the decomposer should point out locations in the layout that are not triple patterning decomposable and therefore manual intervention by designers is required. A traditional decomposition flow would be an iterative process, where each iteration consists of an automatic layout decomposition step and manual layout modification task. However, due to the NP-hardness of triple patterning layout decomposition, automatic full chip level layout decomposition requires long computational time and therefore design closure issues continue to linger around in the traditional flow. Challenged by this issue, we present a novel incremental layout decomposition framework to facilitate accelerated iterative decomposition. In the first iteration, our decomposer not only points out all conflicts, but also provides the suggestions to fix them. After the layout modification, instead of solving the full chip problem from scratch, our decomposer can provide a quick solution for a selected portion of layout. We believe this framework is efficient, in terms of performance and designer friendly.
Further improvements of a new model for turbulent convection in stars
NASA Technical Reports Server (NTRS)
Canuto, V. M.; Mazzitelli, I.
1992-01-01
The effects of including a variable molecular weight and of using the newest opacities of Rogers and Iglesias (1991) as inputs to a recent model by Canuto and Mazzitelli (1991) for stellar turbulent convection are studied. Solar evolutionary tracks are used to conclude that the the original model for turbulence with mixing length Lambda = z, Giuli's variable Q unequal to 1 and the new opacities yields a fit to solar T(eff) within 0.5 percent. A formulation of Lambda is proposed that extends the purely nonlocal Lambda = z expression to include local effects. A new expression for Lambda is obtained which generalizes both the mixing length theory (MLT) phenomenological expression for Lambda as well as the model Lambda = z. It is argued that the MLT should now be abandoned.
Rayleigh, the unit for light radiance.
Baker, D J
1974-09-01
A 0.7% accurate formula is derived for the easy conversion of power spectral radiance L(lambda) in W cm(-2) sr(-1) microm(-1)to rayleigh spectral radiance R(lambda) in rayleigh/microm, R(lambda) = 2pilambdaL(lambda) x 10(13), where the wavelength lambda is in microm. The rationale for the rayleigh unit is discussed in terms of a photon rate factor and a solid angle factor. The latter is developed in terms of an equivalence theorem about optical receivers and extended sources, and the concept is extended to the computation of photon volume emission rates from altitude profiles of zenith radiance.
Acceleration of convergence of vector sequences
NASA Technical Reports Server (NTRS)
Sidi, A.; Ford, W. F.; Smith, D. A.
1983-01-01
A general approach to the construction of convergence acceleration methods for vector sequence is proposed. Using this approach, one can generate some known methods, such as the minimal polynomial extrapolation, the reduced rank extrapolation, and the topological epsilon algorithm, and also some new ones. Some of the new methods are easier to implement than the known methods and are observed to have similar numerical properties. The convergence analysis of these new methods is carried out, and it is shown that they are especially suitable for accelerating the convergence of vector sequences that are obtained when one solves linear systems of equations iteratively. A stability analysis is also given, and numerical examples are provided. The convergence and stability properties of the topological epsilon algorithm are likewise given.
Smith, Jayden A; Collins, J Grant; Patterson, Bradley T; Keene, F Richard
2004-05-07
The binding of the three stereoisomers (DeltaDelta-, LambdaLambda- and DeltaLambda-) of the dinuclear ruthenium(II) complex [[Ru(Me2bpy)2]2(mu-bpm)]4+ [Me2bpy = 4,4'-dimethyl-2,2'-bipyridine; bpm = 2,2'-bipyrimidine] to a tridecanucleotide containing a single adenine bulge has been studied by 1H NMR spectroscopy. The addition of the DeltaDelta-isomer to d(CCGAGAATTCCGG)2 induced significant chemical shift changes for the base and sugar resonances of the residues at the bulge site (G3A4G5/C11C10), whereas small shifts were observed upon addition of the enantiomeric LambdaLambda-form. NOESY spectra of the tridecanucleotide bound with the DeltaDelta-isomer revealed intermolecular NOE's between the metal complex and the nucleotide residues at the bulge site, while only weak NOE's were observed to terminal residues to the LambdaLambda-form. Competitive binding studies were performed where both enantiomers were simultaneously added to the tridecanucleotide, and for all ratios of the two stereoisomers the DeltaDelta-isomer remained selectively bound at the bulge site with the LambdaLambda-enantiomer localised at the terminal regions of the tridecanucleotide. The meso-diastereoisomer (DeltaLambda) was found to bind to the tridecanucleotide with characteristics intermediate between the DeltaDelta- and LambdaLambda-enantiomers of the rac form. Two distinct sets of metal complex resonances were observed, with one set having essentially the same shift as the free metal complex, whilst the other set of resonances exhibited significant shifts. The NOE data indicated that the meso-diastereoisomer does not bind as selectively as the DeltaDelta-isomer, with NOE's observed to a greater number of nucleotide residues compared to the DeltaDelta-form. This study provides a rare example of total enantioselectivity in the binding of an inert transition metal complex to DNA, produced by the shape recognition of both ruthenium(II) centres.
Somatic diversification of chicken immunoglobulin light chains by point mutations.
Parvari, R; Ziv, E; Lantner, F; Heller, D; Schechter, I
1990-04-01
The light-chain locus of chicken has 1 functional V lambda 1 gene, 1 J gene, and 25 pseudo-V lambda-genes (where V = variable and J = joining). A major problem is which somatic mechanisms expand this extremely limited germ-line information to generate many different antibodies. Weill's group [Reynaud, C. A., Anquez, V., Grimal, H. & Weill, J. C. (1987) Cell 48, 379-388] has shown that the pseudo-V lambda-genes diversify the rearranged V lambda 1 by gene conversion. Here we demonstrate that chicken light chains are further diversified by somatic point mutations and by V lambda 1-J flexible joining. Somatic point mutations were identified in the J and 3' noncoding DNA of rearranged light-chain genes of chicken. These regions were analyzed because point mutations in V lambda 1 are obscured by gene conversion; the J and 3' noncoding DNA are presented in one copy per haploid genome and are not subject to gene conversion. In rodents point mutations occur as frequently in the V-J coding regions as in the adjacent flanking DNA. Therefore, we conclude that somatic point mutations diversify the V lambda 1 of chicken. The frequency (0-1%) and distribution of the mutations (decreasing in number with increased distance from the V lambda 1 segment) in chicken were as observed in rodents. Sequence variability at the V lambda 1-J junctions could be attributed to imprecise joining of the V lambda 1 and J genes. The modification by gene conversion of rearranged V lambda 1 genes in the bursa was similar in chicken aged 3 months (9.5%) or 3 weeks (9.1%)--i.e., gene conversion that generates the preimmune repertoire in the bursa seems to level off around 3 weeks of age. This preimmune repertoire can be further diversified by somatic point mutations that presumably lead to the formation of antibodies with increased affinity. A segment with structural features of a matrix association region [(A + T)-rich and four topoisomerase II binding sites] was identified in the middle of the J-C lambda intron (where C = constant).
NASA Astrophysics Data System (ADS)
Niki, Hiroshi; Harada, Kyouji; Morimoto, Munenori; Sakakihara, Michio
2004-03-01
Several preconditioned iterative methods reported in the literature have been used for improving the convergence rate of the Gauss-Seidel method. In this article, on the basis of nonnegative matrix, comparisons between some splittings for such preconditioned matrices are derived. Simple numerical examples are also given.
Conjugate-gradient preconditioning methods for shift-variant PET image reconstruction.
Fessler, J A; Booth, S D
1999-01-01
Gradient-based iterative methods often converge slowly for tomographic image reconstruction and image restoration problems, but can be accelerated by suitable preconditioners. Diagonal preconditioners offer some improvement in convergence rate, but do not incorporate the structure of the Hessian matrices in imaging problems. Circulant preconditioners can provide remarkable acceleration for inverse problems that are approximately shift-invariant, i.e., for those with approximately block-Toeplitz or block-circulant Hessians. However, in applications with nonuniform noise variance, such as arises from Poisson statistics in emission tomography and in quantum-limited optical imaging, the Hessian of the weighted least-squares objective function is quite shift-variant, and circulant preconditioners perform poorly. Additional shift-variance is caused by edge-preserving regularization methods based on nonquadratic penalty functions. This paper describes new preconditioners that approximate more accurately the Hessian matrices of shift-variant imaging problems. Compared to diagonal or circulant preconditioning, the new preconditioners lead to significantly faster convergence rates for the unconstrained conjugate-gradient (CG) iteration. We also propose a new efficient method for the line-search step required by CG methods. Applications to positron emission tomography (PET) illustrate the method.
Large Airborne Full Tensor Gradient Data Inversion Based on a Non-Monotone Gradient Method
NASA Astrophysics Data System (ADS)
Sun, Yong; Meng, Zhaohai; Li, Fengting
2018-03-01
Following the development of gravity gradiometer instrument technology, the full tensor gravity (FTG) data can be acquired on airborne and marine platforms. Large-scale geophysical data can be obtained using these methods, making such data sets a number of the "big data" category. Therefore, a fast and effective inversion method is developed to solve the large-scale FTG data inversion problem. Many algorithms are available to accelerate the FTG data inversion, such as conjugate gradient method. However, the conventional conjugate gradient method takes a long time to complete data processing. Thus, a fast and effective iterative algorithm is necessary to improve the utilization of FTG data. Generally, inversion processing is formulated by incorporating regularizing constraints, followed by the introduction of a non-monotone gradient-descent method to accelerate the convergence rate of FTG data inversion. Compared with the conventional gradient method, the steepest descent gradient algorithm, and the conjugate gradient algorithm, there are clear advantages of the non-monotone iterative gradient-descent algorithm. Simulated and field FTG data were applied to show the application value of this new fast inversion method.
NASA Astrophysics Data System (ADS)
Huang, Xiaomeng; Tang, Qiang; Tseng, Yuheng; Hu, Yong; Baker, Allison H.; Bryan, Frank O.; Dennis, John; Fu, Haohuan; Yang, Guangwen
2016-11-01
In the Community Earth System Model (CESM), the ocean model is computationally expensive for high-resolution grids and is often the least scalable component for high-resolution production experiments. The major bottleneck is that the barotropic solver scales poorly at high core counts. We design a new barotropic solver to accelerate the high-resolution ocean simulation. The novel solver adopts a Chebyshev-type iterative method to reduce the global communication cost in conjunction with an effective block preconditioner to further reduce the iterations. The algorithm and its computational complexity are theoretically analyzed and compared with other existing methods. We confirm the significant reduction of the global communication time with a competitive convergence rate using a series of idealized tests. Numerical experiments using the CESM 0.1° global ocean model show that the proposed approach results in a factor of 1.7 speed-up over the original method with no loss of accuracy, achieving 10.5 simulated years per wall-clock day on 16 875 cores.
Acceleration of the direct reconstruction of linear parametric images using nested algorithms.
Wang, Guobao; Qi, Jinyi
2010-03-07
Parametric imaging using dynamic positron emission tomography (PET) provides important information for biological research and clinical diagnosis. Indirect and direct methods have been developed for reconstructing linear parametric images from dynamic PET data. Indirect methods are relatively simple and easy to implement because the image reconstruction and kinetic modeling are performed in two separate steps. Direct methods estimate parametric images directly from raw PET data and are statistically more efficient. However, the convergence rate of direct algorithms can be slow due to the coupling between the reconstruction and kinetic modeling. Here we present two fast gradient-type algorithms for direct reconstruction of linear parametric images. The new algorithms decouple the reconstruction and linear parametric modeling at each iteration by employing the principle of optimization transfer. Convergence speed is accelerated by running more sub-iterations of linear parametric estimation because the computation cost of the linear parametric modeling is much less than that of the image reconstruction. Computer simulation studies demonstrated that the new algorithms converge much faster than the traditional expectation maximization (EM) and the preconditioned conjugate gradient algorithms for dynamic PET.
Cosmic acceleration and the helicity-0 graviton
DOE Office of Scientific and Technical Information (OSTI.GOV)
Rham, Claudia de; Heisenberg, Lavinia; Gabadadze, Gregory
2011-05-15
We explore cosmology in the decoupling limit of a nonlinear covariant extension of Fierz-Pauli massive gravity obtained recently in arXiv:1007.0443. In this limit the theory is a scalar-tensor model of a unique form defined by symmetries. We find that it admits a self-accelerated solution, with the Hubble parameter set by the graviton mass. The negative pressure causing the acceleration is due to a condensate of the helicity-0 component of the massive graviton, and the background evolution, in the approximation used, is indistinguishable from the {Lambda}CDM model. Fluctuations about the self-accelerated background are stable for a certain range of parameters involved.more » Most surprisingly, the fluctuation of the helicity-0 field above its background decouples from an arbitrary source in the linearized theory. We also show how massive gravity can remarkably screen an arbitrarily large cosmological constant in the decoupling limit, while evading issues with ghosts. The obtained static solution is stable against small perturbations, suggesting that the degravitation of the vacuum energy is possible in the full theory. Interestingly, however, this mechanism postpones the Vainshtein effect to shorter distance scales. Hence, fifth force measurements severely constrain the value of the cosmological constant that can be neutralized, making this scheme phenomenologically not viable for solving the old cosmological constant problem. We briefly speculate on a possible way out of this issue.« less
Tertiary structure of human {Lambda}6 light chains.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Pokkuluri, P. R.; Solomon, A.; Weiss, D. T.
1999-01-01
AL amyloidosis is a disease process characterized by the pathologic deposition of monoclonal light chains in tissue. To date, only limited information has been obtained on the molecular features that render such light chains amyloidogenic. Although protein products of the major human V kappa and V lambda gene families have been identified in AL deposits, one particular subgroup--lambda 6--has been found to be preferentially associated with this disease. Notably, the variable region of lambda 6 proteins (V lambda 6) has distinctive primary structural features including the presence in the third framework region (FR3) of two additional amino acid residues thatmore » distinguish members of this subgroup from other types of light chains. However, the structural consequences of these alterations have not been elucidated. To determine if lambda 6 proteins possess unique tertiary structural features, as compared to light chains of other V lambda subgroups, we have obtained x-ray diffraction data on crystals prepared from two recombinant V lambda 6 molecules. These components, isolated from a bacterial expression system, were generated from lambda 6-related cDNAs cloned from bone marrow-derived plasma cells from a patient (Wil) who had documented AL amyloidosis and another (Jto) with multiple myeloma and tubular cast nephropathy, but no evident fibrillar deposits. The x-ray crystallographic analyses revealed that the two-residue insertion located between positions 68 and 69 (not between 66 and 67 as previously surmised) extended an existing loop region that effectively increased the surface area adjacent to the first complementarity determining region (CDR1). Further, an unusual interaction between the Arg 25 and Phe 2 residues commonly found in lambda 6 molecules was noted. However, the structures of V lambda 6 Wil and Jto also differed from each other, as evidenced by the presence in the latter of certain ionic and hydrophobic interactions that we posit increased protein stability and thus prevented amyloid formation.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kim, Il-Joong; Seon, Kwang-Il; Han, Wonyong
We present the improved far-ultraviolet (FUV) emission-line images of the entire Vela supernova remnant (SNR) using newly processed Spectroscopy of Plasma Evolution from Astrophysical Radiation/Far-Ultraviolet Imaging Spectrograph (SPEAR/FIMS) data. The incomplete C III {lambda}977 and O VI {lambda}{lambda}1032, 1038 images presented in the previous study are updated to cover the whole region. The C IV {lambda}{lambda}1548, 1551 image with a higher resolution and new images at Si IV {lambda}{lambda}1394, 1403, O IV] {lambda}1404, He II {lambda}1640.5, and O III] {lambda}{lambda}1661, 1666 are also shown. Comparison of emission-line ratios for two enhanced FUV regions reveals that the FUV emissions of themore » east-enhanced FUV region may be affected by nonradiative shocks of another very young SNR, the Vela Jr. SNR (RX J0852.0-4622, G266.6-1.2). This result is the first FUV detection that is likely associated with the Vela Jr. SNR, supporting previous arguments that the Vela Jr. SNR is close to us. The comparison of the improved FUV images with soft X-ray images shows that an FUV filamentary feature forms the boundary of the northeast-southwest asymmetrical sections of the X-ray shell. The southwest FUV features are characterized as the region where the Vela SNR is interacting with slightly denser ambient medium within the dim X-ray southwest section. From a comparison with the H{alpha} image, we identify a ring-like H{alpha} feature overlapped with an extended hot X-ray feature of similar size and two local peaks of C IV emission. Their morphologies are expected when the H{alpha} ring is in direct contact with the near or far side of the Vela SNR.« less
Doubling The Intensity Of An ERL Based Light Source
DOE Office of Scientific and Technical Information (OSTI.GOV)
Andrew Hutton
2005-05-01
A light source based on an Energy Recovered Linac (ERL) [1] consists of a superconducting linac and a transfer line that includes wigglers and undulators to produce the synchrotron light. The transfer line brings the electron bunches back to the beginning of the linac so that their energy can be recovered when they traverse the linac a second time, {lambda}/2 out of RF phase. There is another interesting condition when the length of the transfer line is (n {+-} 1/4) {lambda}. In this case, the electrons drift through on the zero RF crossing, and make a further pass around themore » transfer line, effectively doubling the circulating current in the wigglers and undulators. On the third pass through the linac, they will be decelerated and their energy recovered. The longitudinal focusing at the zero crossing is a problem, but it can be canceled if the drifting beam sees a positive energy gradient for the first half of the linac and a negative gradient for the second half (or vice versa). This paper presents a proposal to use a double chicane at the center of the linac to provide this focusing inversion for the drifting beam while leaving the accelerating and decelerating beams on crest. [1] G. R. Neil, et al, Phys. Rev. Let. 84, 662 2000« less
Interstellar Medium Absorption Profile Spectrograph (IMAPS)
NASA Technical Reports Server (NTRS)
Jenkins, E. B.
1985-01-01
The design and fabrication of an objective-grating echelle spectrograph to fly on sounding rockets and record spectra of stars from approximately 920 to 1120A with a resolving power lambda/delta lambda = 200,000 is discussed. The scientific purpose of the program is to observe, with ten times better velocity resolution than before, the plentiful absorption lines in this spectral region produced by atoms, ions and molecules in the interstellar medium. In addition, an important technical goal is to develop and flight-quality a new ultraviolet, photon-counting image sensor which has a windowless, opaque photocathode and a CCD bombarded directly by the accelerated photoelectrons. Except for some initial difficulties with the performance of CCDs, the development of the payload instrument is relatively straightforward and our overall design goals are satisfied. The first flight occurred in late 1984, but no data were obtained because of an inrush of air degraded the instrument's vacuum and caused the detector's high voltage to arc. A second flight in early 1985 was a complete success and obtained a spectrum of pi Sco. Data from this mission are currently being reduced; quick-look versions of the spectra indicate that excellent results will be obtained. Currently, the payload is being reconfigured to fly on a Spartan mission in 1988.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Aubert, B
2004-02-29
Using events in which one of two neutral-B mesons from the decay of an {Upsilon}(4S) resonance is fully reconstructed, we set limits on the difference between the decay rates of the two neutral-B mass eigenstates and on CP, T, and CPT violation in B{sup 0}{bar B}{sup 0} mixing. The reconstructed decays, comprising both CP and flavor eigenstates, are obtained from 88 million {Upsilon}(4S) {yields} B{bar B} decays collected with the BABAR detector at the PEP-II asymmetric-energy B Factory at SLAC. We determine six independent parameters governing oscillations ({Delta}m, {Delta}{Lambda}/{Lambda}), CPT and CP violation (Re z, Im z), and CP andmore » T violation (Im {lambda}{sub CP}, |q/p|), where {lambda}{sub cp} characterizes B{sup 0} and {bar B}{sup 0} decays to states of charmonium plus K{sub S}{sup 0} or K{sub L}{sup 0}. The results are sgn(Re {lambda}{sub CP}){Delta}{Lambda}/{Lambda} = .0.008 {+-} 0.037(stat.) {+-} 0.018(syst.) [-0.084, 0.068], |q/p| = 1.029 {+-} 0.013(stat.) {+-} 0.011(syst.) [1.001, 1.057], (Re {lambda}{sub CP}/|{lambda}{sub CP}|)Re z = 0.014 {+-} 0.035(stat.) {+-} 0.034(syst.) [-0.072, 0.101], Imz = 0.038 {+-} 0.029(stat.) {+-} 0.025(syst.) [-0.028, 0.104]. The values inside square brackets indicate the 90% confidence-level intervals. The values of Im {lambda}{sub CP} and {Delta}m are consistent with previous analyses and are used as cross-checks. These measurements are in agreement with Standard Model expectations.« less
Simple model for lambda-doublet propensities in bimolecular reactions
NASA Technical Reports Server (NTRS)
Bronikowski, Michael J.; Zare, Richard N.
1990-01-01
A simple geometric model is presented to account for lambda-doublet propensities in bimolecular reactions A + BC - AB + C. It applies to reactions in which AB is formed in a pi state, and in which the unpaired molecular orbital responsible for lambda-doubling arises from breaking the B-C bond. The lambda-doublet population ratio is predicted to be 2:1 provided that: (1) the motion of A in the transition state determines the plane of rotation of AB; (2) the unpaired pi orbital lying initially along the B-C bond may be resolved into a projection onto the AB plane of rotation and a projection perpendicular to this plane; (3) there is no preferred geometry for dissociation of ABC. The 2:1 lambda-doublet ratio is the 'unconstrained dynamics prior' lambda-doublet distribution for such reactions.
Effective screening length of isotropic liquid samples submitted to an applied voltage.
Zola, R S; Evangelista, L R; Barbero, G
2006-05-25
A cell of isotropic liquid in the shape of a slab of thickness d and containing ionic impurities is considered. It is shown that the screening effect produced by the ionic charges on the external field is characterized by an effective surface length, lambda(S)(U), depending on the applied voltage U. The analysis indicates that lambda(S)(U)) < lambda(D) when the applied voltage is very large, and lambda(S)(U) --> lambda(D) for very small values of the applied voltage, where lambda(D) is the Debye screening length. The presence of the ions is responsible also for a counterpotential, v, that for small U is such to cancel the effective electric field in the sample, whereas in the opposite limit it is inversely proportional to the applied difference of potential.
The Legacy Archive for Microwave Background Data Analysis (LAMBDA)
NASA Astrophysics Data System (ADS)
Miller, Nathan; LAMBDA
2018-01-01
The Legacy Archive for Microwave Background Data Analysis (LAMBDA) provides CMB researchers with archival data for cosmology missions, software tools, and links to other sites of interest. LAMBDA is one-stop shopping for CMB researchers. It hosts data from WMAP along with many suborbital experiments. Over the past year, LAMBDA has acquired new data from SPTpol, SPIDER and ACTPol. In addition to the primary CMB, LAMBDA also provides foreground data.LAMBDA has several ongoing efforts to provide tools for CMB researchers. These tools include a web interface for CAMB and a web interface for a CMB survey footprint database and plotting tool. Additionally, we have recently developed a Docker container with standard CMB analysis tools and demonstrations in the form of Jupyter notebooks. These containers will be publically available through Docker's container repository and the source will be available on github.
Interferon lambda 1-3 expression in infants hospitalized for RSV or HRV associated bronchiolitis.
Selvaggi, Carla; Pierangeli, Alessandra; Fabiani, Marco; Spano, Lucia; Nicolai, Ambra; Papoff, Paola; Moretti, Corrado; Midulla, Fabio; Antonelli, Guido; Scagnolari, Carolina
2014-05-01
The airway expression of type III interferons (IFNs) was evaluated in infants hospitalized for respiratory syncytial virus (RSV) or rhinovirus (HRV) bronchiolitis. As an additional objective we sought to determine whether a different expression of IFN lambda 1-3 was associated with different harboring viruses, the clinical course of bronchiolitis or with the levels of well established IFN stimulated genes (ISGs), such as mixovirus resistance A (MxA) and ISG56. The analysis was undertaken in 118 infants with RSV or HRV bronchiolitis. Nasopharyngeal washes were collected for virological studies and molecular analysis of type III IFN responses. RSV elicited higher levels of IFN lambda subtypes when compared with HRV. A similar expression of type III IFN was found in RSVA or RSVB infected infants and in those infected with HRVA or HRVC viruses. Results also indicate that IFN lambda 1 and IFN lambda 2-3 levels were correlated with each other and with MxA and ISG56-mRNAs. In addition, a positive correlation exists between the IFN lambda1 levels and the clinical score index during RSV infection. In particular, higher IFN lambda 1 levels are associated to an increase of respiratory rate. These findings show that differences in the IFN lambda 1-3 levels in infants with RSV or HRV infections are present and that the expression of IFN lambda 1 correlates with the severity of RSV bronchiolitis. Copyright © 2014 The British Infection Association. Published by Elsevier Ltd. All rights reserved.
The protein interaction map of bacteriophage lambda
2011-01-01
Background Bacteriophage lambda is a model phage for most other dsDNA phages and has been studied for over 60 years. Although it is probably the best-characterized phage there are still about 20 poorly understood open reading frames in its 48-kb genome. For a complete understanding we need to know all interactions among its proteins. We have manually curated the lambda literature and compiled a total of 33 interactions that have been found among lambda proteins. We set out to find out how many protein-protein interactions remain to be found in this phage. Results In order to map lambda's interactions, we have cloned 68 out of 73 lambda open reading frames (the "ORFeome") into Gateway vectors and systematically tested all proteins for interactions using exhaustive array-based yeast two-hybrid screens. These screens identified 97 interactions. We found 16 out of 30 previously published interactions (53%). We have also found at least 18 new plausible interactions among functionally related proteins. All previously found and new interactions are combined into structural and network models of phage lambda. Conclusions Phage lambda serves as a benchmark for future studies of protein interactions among phage, viruses in general, or large protein assemblies. We conclude that we could not find all the known interactions because they require chaperones, post-translational modifications, or multiple proteins for their interactions. The lambda protein network connects 12 proteins of unknown function with well characterized proteins, which should shed light on the functional associations of these uncharacterized proteins. PMID:21943085
Lagardère, Louis; Lipparini, Filippo; Polack, Étienne; Stamm, Benjamin; Cancès, Éric; Schnieders, Michael; Ren, Pengyu; Maday, Yvon; Piquemal, Jean-Philip
2014-02-28
In this paper, we present a scalable and efficient implementation of point dipole-based polarizable force fields for molecular dynamics (MD) simulations with periodic boundary conditions (PBC). The Smooth Particle-Mesh Ewald technique is combined with two optimal iterative strategies, namely, a preconditioned conjugate gradient solver and a Jacobi solver in conjunction with the Direct Inversion in the Iterative Subspace for convergence acceleration, to solve the polarization equations. We show that both solvers exhibit very good parallel performances and overall very competitive timings in an energy-force computation needed to perform a MD step. Various tests on large systems are provided in the context of the polarizable AMOEBA force field as implemented in the newly developed Tinker-HP package which is the first implementation for a polarizable model making large scale experiments for massively parallel PBC point dipole models possible. We show that using a large number of cores offers a significant acceleration of the overall process involving the iterative methods within the context of spme and a noticeable improvement of the memory management giving access to very large systems (hundreds of thousands of atoms) as the algorithm naturally distributes the data on different cores. Coupled with advanced MD techniques, gains ranging from 2 to 3 orders of magnitude in time are now possible compared to non-optimized, sequential implementations giving new directions for polarizable molecular dynamics in periodic boundary conditions using massively parallel implementations.
Lagardère, Louis; Lipparini, Filippo; Polack, Étienne; Stamm, Benjamin; Cancès, Éric; Schnieders, Michael; Ren, Pengyu; Maday, Yvon; Piquemal, Jean-Philip
2015-01-01
In this paper, we present a scalable and efficient implementation of point dipole-based polarizable force fields for molecular dynamics (MD) simulations with periodic boundary conditions (PBC). The Smooth Particle-Mesh Ewald technique is combined with two optimal iterative strategies, namely, a preconditioned conjugate gradient solver and a Jacobi solver in conjunction with the Direct Inversion in the Iterative Subspace for convergence acceleration, to solve the polarization equations. We show that both solvers exhibit very good parallel performances and overall very competitive timings in an energy-force computation needed to perform a MD step. Various tests on large systems are provided in the context of the polarizable AMOEBA force field as implemented in the newly developed Tinker-HP package which is the first implementation for a polarizable model making large scale experiments for massively parallel PBC point dipole models possible. We show that using a large number of cores offers a significant acceleration of the overall process involving the iterative methods within the context of spme and a noticeable improvement of the memory management giving access to very large systems (hundreds of thousands of atoms) as the algorithm naturally distributes the data on different cores. Coupled with advanced MD techniques, gains ranging from 2 to 3 orders of magnitude in time are now possible compared to non-optimized, sequential implementations giving new directions for polarizable molecular dynamics in periodic boundary conditions using massively parallel implementations. PMID:26512230
WE-AB-303-09: Rapid Projection Computations for On-Board Digital Tomosynthesis in Radiation Therapy
DOE Office of Scientific and Technical Information (OSTI.GOV)
Iliopoulos, AS; Sun, X; Pitsianis, N
2015-06-15
Purpose: To facilitate fast and accurate iterative volumetric image reconstruction from limited-angle on-board projections. Methods: Intrafraction motion hinders the clinical applicability of modern radiotherapy techniques, such as lung stereotactic body radiation therapy (SBRT). The LIVE system may impact clinical practice by recovering volumetric information via Digital Tomosynthesis (DTS), thus entailing low time and radiation dose for image acquisition during treatment. The DTS is estimated as a deformation of prior CT via iterative registration with on-board images; this shifts the challenge to the computational domain, owing largely to repeated projection computations across iterations. We address this issue by composing efficient digitalmore » projection operators from their constituent parts. This allows us to separate the static (projection geometry) and dynamic (volume/image data) parts of projection operations by means of pre-computations, enabling fast on-board processing, while also relaxing constraints on underlying numerical models (e.g. regridding interpolation kernels). Further decoupling the projectors into simpler ones ensures the incurred memory overhead remains low, within the capacity of a single GPU. These operators depend only on the treatment plan and may be reused across iterations and patients. The dynamic processing load is kept to a minimum and maps well to the GPU computational model. Results: We have integrated efficient, pre-computable modules for volumetric ray-casting and FDK-based back-projection with the LIVE processing pipeline. Our results show a 60x acceleration of the DTS computations, compared to the previous version, using a single GPU; presently, reconstruction is attained within a couple of minutes. The present implementation allows for significant flexibility in terms of the numerical and operational projection model; we are investigating the benefit of further optimizations and accurate digital projection sub-kernels. Conclusion: Composable projection operators constitute a versatile research tool which can greatly accelerate iterative registration algorithms and may be conducive to the clinical applicability of LIVE. National Institutes of Health Grant No. R01-CA184173; GPU donation by NVIDIA Corporation.« less
Reconstruction of multiple-pinhole micro-SPECT data using origin ensembles.
Lyon, Morgan C; Sitek, Arkadiusz; Metzler, Scott D; Moore, Stephen C
2016-10-01
The authors are currently developing a dual-resolution multiple-pinhole microSPECT imaging system based on three large NaI(Tl) gamma cameras. Two multiple-pinhole tungsten collimator tubes will be used sequentially for whole-body "scout" imaging of a mouse, followed by high-resolution (hi-res) imaging of an organ of interest, such as the heart or brain. Ideally, the whole-body image will be reconstructed in real time such that data need only be acquired until the area of interest can be visualized well-enough to determine positioning for the hi-res scan. The authors investigated the utility of the origin ensemble (OE) algorithm for online and offline reconstructions of the scout data. This algorithm operates directly in image space, and can provide estimates of image uncertainty, along with reconstructed images. Techniques for accelerating the OE reconstruction were also introduced and evaluated. System matrices were calculated for our 39-pinhole scout collimator design. SPECT projections were simulated for a range of count levels using the MOBY digital mouse phantom. Simulated data were used for a comparison of OE and maximum-likelihood expectation maximization (MLEM) reconstructions. The OE algorithm convergence was evaluated by calculating the total-image entropy and by measuring the counts in a volume-of-interest (VOI) containing the heart. Total-image entropy was also calculated for simulated MOBY data reconstructed using OE with various levels of parallelization. For VOI measurements in the heart, liver, bladder, and soft-tissue, MLEM and OE reconstructed images agreed within 6%. Image entropy converged after ∼2000 iterations of OE, while the counts in the heart converged earlier at ∼200 iterations of OE. An accelerated version of OE completed 1000 iterations in <9 min for a 6.8M count data set, with some loss of image entropy performance, whereas the same dataset required ∼79 min to complete 1000 iterations of conventional OE. A combination of the two methods showed decreased reconstruction time and no loss of performance when compared to conventional OE alone. OE-reconstructed images were found to be quantitatively and qualitatively similar to MLEM, yet OE also provided estimates of image uncertainty. Some acceleration of the reconstruction can be gained through the use of parallel computing. The OE algorithm is useful for reconstructing multiple-pinhole SPECT data and can be easily modified for real-time reconstruction.
Risk assessment of lambda-cyhalothrin on aquatic organisms in paddy field in China.
Gu, Bao G; Wang, Hui M; Chen, William L; Cai, Dao J; Shan, Zheng J
2007-06-01
This study was carried out to assess the risk of lambda-cyhalothrin to aquatic organisms used in paddy field, and to provide assistance in the ecological risk management of lambda-cyhalothrin. The acute toxicities of five individual formulations of lambda-cyhalothrin to four aquatic species were investigated in the laboratory, as well as in a simulated paddy field-pond ecosystem, and the results implicated that lambda-cyhalothrin is highly toxic to fish, and to a greater extent to shrimp. There were differences in the toxicities to each aquatic organisms among different formulations. lambda-Cyhalothrin degraded rapidly in the environment, with half-lives of different formulations in paddy field water (0.23-0.53 days), pond water (0.38-0.63 days), and paddy field soil (0.96-7.35 days), respectively. The water overflow from the paddy field following a simulated rainstorm 12h after application of lambda-cyhalothrin did not cause injury to fish, clam or crab, but was severely hazardous to shrimp. Additionally, no injury to shrimp was found when simulated overflow occurred 4 days after application. These results suggest that the environmental risk of lambda-cyhalothrin to aquatic organisms can be reduced by (1) developing a relatively safe formulation such as a suspension concentrate, and/or (2) controlling the drainage time of the paddy field.
Brown, E.J.; Baldasaro, P.F.; Dziendziel, R.J.
1997-12-23
A filter system to transmit short wavelength radiation and reflect long wavelength radiation for a thermophotovoltaic energy conversion cell comprises an optically transparent substrate segregation layer with at least one coherent wavelength in optical thickness; a dielectric interference filter deposited on one side of the substrate segregation layer, the interference filter being disposed toward the source of radiation, the interference filter including a plurality of alternating layers of high and low optical index materials adapted to change from transmitting to reflecting at a nominal wavelength {lambda}{sub IF} approximately equal to the bandgap wavelength {lambda}{sub g} of the thermophotovoltaic cell, the interference filter being adapted to transmit incident radiation from about 0.5{lambda}{sub IF} to {lambda}{sub IF} and reflect from {lambda}{sub IF} to about 2{lambda}{sub IF}; and a high mobility plasma filter deposited on the opposite side of the substrate segregation layer, the plasma filter being adapted to start to become reflecting at a wavelength of about 1.5{lambda}{sub IF}. 10 figs.
On the ordinary quiver of the symmetric group over a field of characteristic 2
NASA Astrophysics Data System (ADS)
Martin, Stuart; Russell, Lee
1997-11-01
Let [fraktur S]n and [fraktur A]n denote the symmetric and alternating groups of degree n[set membership][open face N] respectively. Let p be a prime number and let F be an arbitrary field of characteristic p. We say that a partition of n is p-regular if no p (non-zero) parts of it are equal; otherwise we call it p-singular. Let S[lambda]F denote the Specht module corresponding to [lambda]. For [lambda] a p-regular partition of n let D[lambda]F denote the unique irreducible top factor of S[lambda]F. Denote by [Delta][lambda]F =D[lambda]F [downward arrow][fraktur A]n its restriction to [fraktur A]n. Recall also that, over F, the ordinary quiver of the modular group algebra FG is a finite directed graph defined as follows: the vertices are labelled by the set of all simple FG-modules, L1, [ctdot], Lr, and the number of arrows from Li to Lj equals dimFExtFG(Li, Lj). The quiver gives important information about the block structure of G.
The anomalous C 4 intensity ratio in symbiotic stars
NASA Technical Reports Server (NTRS)
Michalitsianos, A. G.; Kafatos, M.; Fahey, R. P.
1988-01-01
The C IV lambda lambda 1548.2,1550.8 resonance doublet in a symbiotic stars was shown to exhibit anomalous line intensity ratios in which I (lambda 1548.2)/I(lambda 1550.8) less than 1, or less than the optically-thick limit of unity. The R Aquarii-central HII region and RX Puppis exhibit this phenomena. The I(lambda 1548.2)/I(lambda 1550.8) ratio in RX Puppis is found to vary inversely with the total C IV line intensity, and with the FES-visual light, as the object declined over a 5 yr period following a brightening in UV and optical emission which peaked in 1982. This doublet intensity behavior could be explained by a wind which has a narrow velocity range of 600 approx. less than sup v wind approx. less than 1000 km/sec, or by the pumping of the Fe II (mul. 45.01) transition a sup 4 F sub 9/2 - y sup 4 H(o) sub 11/2 by C IV lambda 1548.2, which effectively scatters C IV photons into the Fe II spectrum in these objects.
Absorption of {Lambda}(1520) hyperons in photon-nucleus collisions
DOE Office of Scientific and Technical Information (OSTI.GOV)
Paryev, E. Ya.
2012-12-15
In the framework of the nuclear spectral function approach for incoherent primary photon-nucleon and secondary pion-nucleon production processes we study the inclusive {Lambda}(1520)-hyperon production in the interaction of 2-GeV photons with nuclei. In particular, the A and momentum dependences of the absolute and relative {Lambda}(1520)-hyperon yields are investigated in two scenarios for its in-medium width. Our model calculations show that the pion-nucleon production channel contributes appreciably to the {Lambda}(1520) creation at intermediate momenta both in light and heavy nuclei in the chosen kinematics and, hence, has to be taken into consideration on close examination of the dependences of the {Lambda}(1520)-hyperonmore » yields on the target mass number with the aim to get information on its width in the medium. They also demonstrate that the A and momentum dependences of the absolute and relative {Lambda}(1520)-hyperon production cross sections at incident energy of interest are markedly sensitive to the {Lambda}(1520) in-medium width, which means that these observables may be an important tool to determine the above width.« less
Accounting for measurement error in log regression models with applications to accelerated testing.
Richardson, Robert; Tolley, H Dennis; Evenson, William E; Lunt, Barry M
2018-01-01
In regression settings, parameter estimates will be biased when the explanatory variables are measured with error. This bias can significantly affect modeling goals. In particular, accelerated lifetime testing involves an extrapolation of the fitted model, and a small amount of bias in parameter estimates may result in a significant increase in the bias of the extrapolated predictions. Additionally, bias may arise when the stochastic component of a log regression model is assumed to be multiplicative when the actual underlying stochastic component is additive. To account for these possible sources of bias, a log regression model with measurement error and additive error is approximated by a weighted regression model which can be estimated using Iteratively Re-weighted Least Squares. Using the reduced Eyring equation in an accelerated testing setting, the model is compared to previously accepted approaches to modeling accelerated testing data with both simulations and real data.
Spectroscopic Research of Lambda Hypdernuclei at JLab Hall C
NASA Astrophysics Data System (ADS)
Gogami, T.; Achenbach, P.; Ahmidouch, A.; Albayrak, I.; Androic, D.; Asaturyan, A.; Asaturyan, R.; Ates, O.; Baturin, P.; Badui, R.; Boeglin, W.; Bono, J.; Brash, E.; Carter, P.; Chen, C.; Chiba, A.; Christy, E.; Dalton, M.; Danagoulian, S.; De Leo, R.; Doi, D.; Elaasar, M.; Ent, R.; Fujii, Y.; Furic, M.; Gabrielyan, M.; Gan, L.; Garibaldi, F.; Gaskell, D.; Gasparian, A.; Hashimoto, O.; Horn, T.; Hu, B.; Hungerford, Ed. V.; Jones, M.; Kanda, H.; Kaneta, M.; Kato, S.; Kawai, M.; Kawama, D.; Khanal, H.; Kohl, M.; Liyanage, A.; Luo, W.; Maeda, K.; Margaryan, A.; Markowitz, P.; Maruta, T.; Matsumura, A.; Maxwell, V.; Mkrtchyan, A.; Mkrtchyan, H.; Nagao, S.; Nakamura, S. N.; Narayan, A.; Neville, C.; Niculescu, G.; Niculescu, M. I.; Nunez, A.; Nuruzzaman; Okayasu, Y.; Petkovic, T.; Pochodzalla, J.; Qiu, X.; Reinhold, J.; Rodriguez, V. M.; Samanta, C.; Sawatzky, B.; Seva, T.; Shichijo, A.; Tadevosyan, V.; Tang, L.; Taniya, N.; Tsukada, K.; Veilleux, M.; Vulcan, W.; Wesselmann, F. R.; Wood, S. A.; Yamamoto, T.; Ya, L.; Ye, Z.; Yokota, K.; Yuan, L.; Zhamkochyan, S.; Zhu, L.
A Λ hyperon which has a strangeness can be bound in deep inside of a nucleus since a Λ does not suffer from the Pauli exclusion principle from nucleons. Thus, a Λ could be a useful tool to investigate inside of a nucleus. Since 2000, Λ hypernuclear spectroscopic experiments by the (e,e'k) reaction have been performed at the experimental hall C in Thomas Jefferson National Accelerator Facility (JLab Hall C). An experiment, JLab E05-115 was carried out to investigate Λ hypernuclei with a wide mass range (the mass number, A = 7, 9, 10, 12, 52). The latest analysis status of JLab E05-115 experiment is discussed in the present article.
Photoproduction of Λ and Σ 0 hyperons using linearly polarized photons
Paterson, C. A.; Ireland, D. G.; Livingston, K.; ...
2016-06-08
Measurements of polarization observables for the reactionsmore » $$\\vec{\\gamma} p \\rightarrow K^+ \\Lambda$$ and $$\\vec{\\gamma} p \\rightarrow K^+ \\Sigma^0$$ have been performed. This is part of a programme of measurements designed to study the spectrum of baryon resonances. The accurate measurement of several polarization observables provides tight constraints for phenomenological fits. Beam-recoil observables for the $$\\vec{\\gamma} p \\rightarrow K^+ \\Sigma^0$$ reaction have not been reported before now. Furthermore, the measurements were carried out using linearly polarized photon beams and the CLAS detector at the Thomas Jefferson National Accelerator Facility. The energy range of the results is 1.71GeV.« less
Realization of Comfortable Massage by Using Iterative Learning Control Based on EEG
NASA Astrophysics Data System (ADS)
Teramae, Tatsuya; Kushida, Daisuke; Takemori, Fumiaki; Kitamura, Akira
Recently the massage chair is used by a lot of people because they are able to use it easily at home. However a present massage chair only realizes the massage motion. Moreover the massage chair can not consider the user’s condition and massage force. On the other hand, the professional masseur is according to presume the mental condition by patient’s reaction. Then this paper proposes the method of applying masseur’s procedure for the massage chair using iterative learning control based on EEG. And massage force is estimated by acceleration sensor. The realizability of the proposed method is verified by the experimental works using the massage chair.
ANOTHER LOOK AT THE FAST ITERATIVE SHRINKAGE/THRESHOLDING ALGORITHM (FISTA)*
Kim, Donghwan; Fessler, Jeffrey A.
2017-01-01
This paper provides a new way of developing the “Fast Iterative Shrinkage/Thresholding Algorithm (FISTA)” [3] that is widely used for minimizing composite convex functions with a nonsmooth term such as the ℓ1 regularizer. In particular, this paper shows that FISTA corresponds to an optimized approach to accelerating the proximal gradient method with respect to a worst-case bound of the cost function. This paper then proposes a new algorithm that is derived by instead optimizing the step coefficients of the proximal gradient method with respect to a worst-case bound of the composite gradient mapping. The proof is based on the worst-case analysis called Performance Estimation Problem in [11]. PMID:29805242
NASA Technical Reports Server (NTRS)
Rodgers, M. O.; Bradshaw, J. D.; Sandholm, S. T.; Kesheng, S.; Davis, D. D.
1985-01-01
A number of techniques have been proposed for detecting atmospheric OH radicals. Of these, the laser-induced fluorescence (LIF) technique has been used by the largest number of investigators. One of the problems arising in connection with the implementation of this technique is related to the perturbing effect of the UV (lambda approximately 282 nm) laser beam used for OH monitoring, while another problem relates to signal extraction. Several new LIF approaches have been or are currently under development with the objective to bring both problems under control. The present paper deals with the experimental features of one of these new approaches. The considered approach is referred to as 2-lambda laser-induced fluorescence (2-lambda LIF). It is shown that the 2-lambda LIF system provides significant advantages over earlier 1-lambda LIF OH measurement instruments operating at ambient pressure.
Zhu, Sha; Degnan, James H; Goldstien, Sharyn J; Eldon, Bjarki
2015-09-15
There has been increasing interest in coalescent models which admit multiple mergers of ancestral lineages; and to model hybridization and coalescence simultaneously. Hybrid-Lambda is a software package that simulates gene genealogies under multiple merger and Kingman's coalescent processes within species networks or species trees. Hybrid-Lambda allows different coalescent processes to be specified for different populations, and allows for time to be converted between generations and coalescent units, by specifying a population size for each population. In addition, Hybrid-Lambda can generate simulated datasets, assuming the infinitely many sites mutation model, and compute the F ST statistic. As an illustration, we apply Hybrid-Lambda to infer the time of subdivision of certain marine invertebrates under different coalescent processes. Hybrid-Lambda makes it possible to investigate biogeographic concordance among high fecundity species exhibiting skewed offspring distribution.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Deur, Alexandre; Brodsky, Stanley J.; de Téramond, Guy F.
Here, the recent determination of themore » $$\\beta$$--function of the QCD running coupling $$\\alpha_{\\overline{MS}}(Q^2)$$ to five-loops, provides a verification of the convergence of a novel method for determining the fundamental QCD parameter $$\\Lambda_s$$ based on the Light-Front Holographic approach to nonperturbative QCD. The new 5-loop analysis, together with improvements in determining the holographic QCD nonperturbative scale parameter $$\\kappa$$ from hadronic spectroscopy, leads to an improved precision of the value of $$\\Lambda_s$$ in the $${\\overline{MS}}$$ scheme close to a factor of two; we find $$\\Lambda^{(3)}_{\\overline{MS}}=0.339\\pm0.019$$ GeV for $$n_{f}=3$$, in excellent agreement with the world average, $$\\Lambda_{\\overline{MS}}^{(3)}=0.332\\pm0.017$$ GeV. Lastly, we also discuss the constraints imposed on the scale dependence of the strong coupling in the nonperturbative domain by superconformal quantum mechanics and its holographic embedding in anti-de Sitter space.« less
Simultaneous display of two large proteins on the head and tail of bacteriophage lambda.
Pavoni, Emiliano; Vaccaro, Paola; D'Alessio, Valeria; De Santis, Rita; Minenkova, Olga
2013-09-30
Consistent progress in the development of bacteriophage lambda display platform as an alternative to filamentous phage display system was achieved in the recent years. The lambda phage has been engineered to display efficiently multiple copies of peptides or even large protein domains providing a powerful tool for screening libraries of peptides, proteins and cDNA. In the present work we describe an original method for dual display of large proteins on the surface of lambda particles. An anti-CEA single-chain antibody fragment and green fluorescent protein or alkaline phosphatase were simultaneously displayed by engineering both gpD and gpV lambda proteins. Here we show that such modified phage particles can be used for the detection of target molecules in vitro and in vivo. Dual expression of functional moieties on the surface of the lambda phage might open the way to generation of a new class of diagnostic and therapeutic targeted nanoparticles.
NASA Technical Reports Server (NTRS)
Angart, Samuel; Lauer, Mark; Poirier, David; Tewari, Surendra; Rajamure, Ravi; Grugel, Richard
2015-01-01
Samples from directionally solidified Al- 7 wt. % Si have been analyzed for primary dendrite arm spacing (lambda) and radial macrosegregation. The alloy was directionally solidified (DS) aboard the ISS to determine the effect of mitigating convection on lambda and macrosegregation. Samples from terrestrial DS-experiments thermal histories are discussed for comparison. In some experiments, lambda was measured in microstructures that developed during the transition from one speed to another. To represent DS in the presence of no convection, the Hunt-Lu model was used to represent diffusion controlled growth under steady-state conditions. By sectioning cross-sections throughout the entire length of a solidified sample, lambda was measured and calculated using the model. During steady-state, there was reasonable agreement between the measured and calculated lambda's in the space-grown samples. In terrestrial samples, the differences between measured and calculated lambda's indicated that the dendritic growth was influenced by convection.
Aaltonen, T; Adelman, J; Alvarez González, B; Amerio, S; Amidei, D; Anastassov, A; Annovi, A; Antos, J; Apollinari, G; Apresyan, A; Arisawa, T; Artikov, A; Asaadi, J; Ashmanskas, W; Attal, A; Aurisano, A; Azfar, F; Badgett, W; Barbaro-Galtieri, A; Barnes, V E; Barnett, B A; Barria, P; Bartos, P; Bauer, G; Beauchemin, P-H; Bedeschi, F; Beecher, D; Behari, S; Bellettini, G; Bellinger, J; Benjamin, D; Beretvas, A; Bhatti, A; Binkley, M; Bisello, D; Bizjak, I; Blair, R E; Blocker, C; Blumenfeld, B; Bocci, A; Bodek, A; Boisvert, V; Bortoletto, D; Boudreau, J; Boveia, A; Brau, B; Bridgeman, A; Brigliadori, L; Bromberg, C; Brubaker, E; Budagov, J; Budd, H S; Budd, S; Burkett, K; Busetto, G; Bussey, P; Buzatu, A; Byrum, K L; Cabrera, S; Calancha, C; Camarda, S; Campanelli, M; Campbell, M; Canelli, F; Canepa, A; Carls, B; Carlsmith, D; Carosi, R; Carrillo, S; Carron, S; Casal, B; Casarsa, M; Castro, A; Catastini, P; Cauz, D; Cavaliere, V; Cavalli-Sforza, M; Cerri, A; Cerrito, L; Chang, S H; Chen, Y C; Chertok, M; Chiarelli, G; Chlachidze, G; Chlebana, F; Cho, K; Chokheli, D; Chou, J P; Chung, K; Chung, W H; Chung, Y S; Chwalek, T; Ciobanu, C I; Ciocci, M A; Clark, A; Clark, D; Compostella, G; Convery, M E; Conway, J; Corbo, M; Cordelli, M; Cox, C A; Cox, D J; Crescioli, F; Cuenca Almenar, C; Cuevas, J; Culbertson, R; Cully, J C; Dagenhart, D; Datta, M; Davies, T; de Barbaro, P; De Cecco, S; Deisher, A; De Lorenzo, G; Dell'Orso, M; Deluca, C; Demortier, L; Deng, J; Deninno, M; d'Errico, M; Di Canto, A; di Giovanni, G P; Di Ruzza, B; Dittmann, J R; D'Onofrio, M; Donati, S; Dong, P; Dorigo, T; Dube, S; Ebina, K; Elagin, A; Erbacher, R; Errede, D; Errede, S; Ershaidat, N; Eusebi, R; Fang, H C; Farrington, S; Fedorko, W T; Feild, R G; Feindt, M; Fernandez, J P; Ferrazza, C; Field, R; Flanagan, G; Forrest, R; Frank, M J; Franklin, M; Freeman, J C; Furic, I; Gallinaro, M; Galyardt, J; Garberson, F; Garcia, J E; Garfinkel, A F; Garosi, P; Gerberich, H; Gerdes, D; Gessler, A; Giagu, S; Giakoumopoulou, V; Giannetti, P; Gibson, K; Gimmell, J L; Ginsburg, C M; Giokaris, N; Giordani, M; Giromini, P; Giunta, M; Giurgiu, G; Glagolev, V; Glenzinski, D; Gold, M; Goldschmidt, N; Golossanov, A; Gomez, G; Gomez-Ceballos, G; Goncharov, M; González, O; Gorelov, I; Goshaw, A T; Goulianos, K; Gresele, A; Grinstein, S; Grosso-Pilcher, C; Group, R C; Grundler, U; Guimaraes da Costa, J; Gunay-Unalan, Z; Haber, C; Hahn, S R; Halkiadakis, E; Han, B-Y; Han, J Y; Happacher, F; Hara, K; Hare, D; Hare, M; Harr, R F; Hartz, M; Hatakeyama, K; Hays, C; Heck, M; Heinrich, J; Herndon, M; Heuser, J; Hewamanage, S; Hidas, D; Hill, C S; Hirschbuehl, D; Hocker, A; Hou, S; Houlden, M; Hsu, S-C; Hughes, R E; Hurwitz, M; Husemann, U; Hussein, M; Huston, J; Incandela, J; Introzzi, G; Iori, M; Ivanov, A; James, E; Jang, D; Jayatilaka, B; Jeon, E J; Jha, M K; Jindariani, S; Johnson, W; Jones, M; Joo, K K; Jun, S Y; Jung, J E; Junk, T R; Kamon, T; Kar, D; Karchin, P E; Kato, Y; Kephart, R; Ketchum, W; Keung, J; Khotilovich, V; Kilminster, B; Kim, D H; Kim, H S; Kim, H W; Kim, J E; Kim, M J; Kim, S B; Kim, S H; Kim, Y K; Kimura, N; Kirsch, L; Klimenko, S; Kondo, K; Kong, D J; Konigsberg, J; Korytov, A; Kotwal, A V; Kreps, M; Kroll, J; Krop, D; Krumnack, N; Kruse, M; Krutelyov, V; Kuhr, T; Kulkarni, N P; Kurata, M; Kwang, S; Laasanen, A T; Lami, S; Lammel, S; Lancaster, M; Lander, R L; Lannon, K; Lath, A; Latino, G; Lazzizzera, I; LeCompte, T; Lee, E; Lee, H S; Lee, J S; Lee, S W; Leone, S; Lewis, J D; Lin, C-J; Linacre, J; Lindgren, M; Lipeles, E; Lister, A; Litvintsev, D O; Liu, C; Liu, T; Lockyer, N S; Loginov, A; Lovas, L; Lucchesi, D; Lueck, J; Lujan, P; Lukens, P; Lungu, G; Lys, J; Lysak, R; MacQueen, D; Madrak, R; Maeshima, K; Makhoul, K; Maksimovic, P; Malde, S; Malik, S; Manca, G; Manousakis-Katsikakis, A; Margaroli, F; Marino, C; Marino, C P; Martin, A; Martin, M S; Martin, V; Martínez, M; Martínez-Ballarín, R; Mastrandrea, P; Mathis, M; Mattson, M E; Mazzanti, P; McFarland, K S; McIntyre, P; McNulty, R; Mehta, A; Mehtala, P; Menzione, A; Mesropian, C; Miao, T; Mietlicki, D; Miladinovic, N; Miller, R; Mills, C; Milnik, M; Mitra, A; Mitselmakher, G; Miyake, H; Moed, S; Moggi, N; Mondragon, M N; Moon, C S; Moore, R; Morello, M J; Morlock, J; Movilla Fernandez, P; Mülmenstädt, J; Mukherjee, A; Muller, Th; Mumford, R; Murat, P; Mussini, M; Nachtman, J; Nagai, Y; Naganoma, J; Nakamura, K; Nakano, I; Napier, A; Nett, J; Neu, C; Neubauer, M S; Neubauer, S; Nielsen, J; Nodulman, L; Norman, M; Norniella, O; Nurse, E; Oakes, L; Oh, S H; Oh, Y D; Oksuzian, I; Okusawa, T; Orava, R; Osterberg, K; Pagan Griso, S; Pagliarone, C; Palencia, E; Papadimitriou, V; Papaikonomou, A; Paramanov, A A; Parks, B; Pashapour, S; Patrick, J; Pauletta, G; Paulini, M; Paus, C; Peiffer, T; Pellett, D E; Penzo, A; Phillips, T J; Piacentino, G; Pianori, E; Pinera, L; Pitts, K; Plager, C; Pondrom, L; Potamianos, K; Poukhov, O; Prokoshin, F; Pronko, A; Ptohos, F; Pueschel, E; Punzi, G; Pursley, J; Rademacker, J; Rahaman, A; Ramakrishnan, V; Ranjan, N; Redondo, I; Renton, P; Renz, M; Rescigno, M; Richter, S; Rimondi, F; Ristori, L; Robson, A; Rodrigo, T; Rodriguez, T; Rogers, E; Rolli, S; Roser, R; Rossi, M; Rossin, R; Roy, P; Ruiz, A; Russ, J; Rusu, V; Rutherford, B; Saarikko, H; Safonov, A; Sakumoto, W K; Santi, L; Sartori, L; Sato, K; Savoy-Navarro, A; Schlabach, P; Schmidt, A; Schmidt, E E; Schmidt, M A; Schmidt, M P; Schmitt, M; Schwarz, T; Scodellaro, L; Scribano, A; Scuri, F; Sedov, A; Seidel, S; Seiya, Y; Semenov, A; Sexton-Kennedy, L; Sforza, F; Sfyrla, A; Shalhout, S Z; Shears, T; Shepard, P F; Shimojima, M; Shiraishi, S; Shochet, M; Shon, Y; Shreyber, I; Simonenko, A; Sinervo, P; Sisakyan, A; Slaughter, A J; Slaunwhite, J; Sliwa, K; Smith, J R; Snider, F D; Snihur, R; Soha, A; Somalwar, S; Sorin, V; Squillacioti, P; Stanitzki, M; St Denis, R; Stelzer, B; Stelzer-Chilton, O; Stentz, D; Strologas, J; Strycker, G L; Suh, J S; Sukhanov, A; Suslov, I; Taffard, A; Takashima, R; Takeuchi, Y; Tanaka, R; Tang, J; Tecchio, M; Teng, P K; Thom, J; Thome, J; Thompson, G A; Thomson, E; Tipton, P; Ttito-Guzmán, P; Tkaczyk, S; Toback, D; Tokar, S; Tollefson, K; Tomura, T; Tonelli, D; Torre, S; Torretta, D; Totaro, P; Tourneur, S; Trovato, M; Tsai, S-Y; Tu, Y; Turini, N; Ukegawa, F; Uozumi, S; van Remortel, N; Varganov, A; Vataga, E; Vázquez, F; Velev, G; Vellidis, C; Vidal, M; Vila, I; Vilar, R; Vogel, M; Volobouev, I; Volpi, G; Wagner, P; Wagner, R G; Wagner, R L; Wagner, W; Wagner-Kuhr, J; Wakisaka, T; Wallny, R; Wang, S M; Warburton, A; Waters, D; Weinberger, M; Weinelt, J; Wester, W C; Whitehouse, B; Whiteson, D; Wicklund, A B; Wicklund, E; Wilbur, S; Williams, G; Williams, H H; Wilson, P; Winer, B L; Wittich, P; Wolbers, S; Wolfe, C; Wolfe, H; Wright, T; Wu, X; Würthwein, F; Yagil, A; Yamamoto, K; Yamaoka, J; Yang, U K; Yang, Y C; Yao, W M; Yeh, G P; Yi, K; Yoh, J; Yorita, K; Yoshida, T; Yu, G B; Yu, I; Yu, S S; Yun, J C; Zanetti, A; Zeng, Y; Zhang, X; Zheng, Y; Zucchelli, S
2010-03-12
We report a measurement of the lifetime of the Lambda(b)(0) baryon in decays to the Lambda(c)(+)pi(-) final state in a sample corresponding to 1.1 fb(-1) collected in pp collisions at square root of s = 1.96 TeV by the CDF II detector at the Tevatron collider. Using a sample of about 3000 fully reconstructed Lambda(b)(0) events we measure tau(Lambda(b)(0)) = 1.401 +/- 0.046(stat) +/- 0.035(syst) ps (corresponding to ctau(Lambda(b)(0)) = 420.1 +/- 13.7(stat) +/- 10.6(syst) microm, where c is the speed of light). The ratio of this result and the world average B(0) lifetime yields tau(Lambda(b)(0))/tau(B(0)) = 0.918 +/- 0.038 (stat) and (syst), in good agreement with recent theoretical predictions.
{Lambda}K*{Lambda}(1116) photoproduction and nucleon resonances
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kim, Sang-Ho; Kim, Hyun-Chul; Nam, Seung-il
2011-10-21
In this presentation, we report our recent studies on the {Lambda}K*{Lambda}(1116) photoproduction off the proton target, using the tree-level Born approximation, via the effective Lagrangian approach. In addition, we include the nine (three- or four-star confirmed) nucleon resonances below the threshold {radical}(s{sub th}){approx_equal}2008 MeV, to interpret the discrepancy between the experiment and previous theoretical studies, in the vicinity of the threshold region. From the numerical studies, we observe that the S{sub 11}(1535) and S11(1650) play an important role for the cross-section enhancement near the {radical}(s{sub th}). It also turns out that, in order to reproduce the data, we have themore » vector coupling constants gK*S{sub 11}(1535){Lambda} = (7.0{approx}9.0) and gK*S{sub 11}(1650){Lambda} (5.0{approx}6.0).« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Oezay, H.; Yildiz, M., E-mail: myildiz@comu.edu.tr; Uenver, H.
2013-01-15
The compound called 3-methoxy-2- [(2,4,4,6,6-pentachloro-1,3,5,2{lambda}{sup 5},4{lambda}{sup 5},6{lambda}{sup 5}-triazatriphosphin-2-yl)oxy] benzaldehyde has been synthesized from the reaction of 2-hydroxy-3-methoxybenzaldehyde with hexachlorocyclotriphosphazene. It has been characterized by elemental analysis, MS, IR, {sup 1}H NMR, {sup 13}C NMR, {sup 31}P NMR and UV-visible spectroscopic techniques. The structure of the title compound has been determind by X-ray analysis. Crystals are orthorhombic, space group P2{sub 1}2{sub 1}2{sub 1}, Z = 4, a = 7.705(1), b = 12.624(1), c = 17.825(2) A, R{sub 1} = 0.0390 and wR{sub 2} = 0.1074 [I > 2{sigma}(I)], respectively.
A RADIATION TRANSFER SOLVER FOR ATHENA USING SHORT CHARACTERISTICS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Davis, Shane W.; Stone, James M.; Jiang Yanfei
2012-03-01
We describe the implementation of a module for the Athena magnetohydrodynamics (MHD) code that solves the time-independent, multi-frequency radiative transfer (RT) equation on multidimensional Cartesian simulation domains, including scattering and non-local thermodynamic equilibrium (LTE) effects. The module is based on well known and well tested algorithms developed for modeling stellar atmospheres, including the method of short characteristics to solve the RT equation, accelerated Lambda iteration to handle scattering and non-LTE effects, and parallelization via domain decomposition. The module serves several purposes: it can be used to generate spectra and images, to compute a variable Eddington tensor (VET) for full radiationmore » MHD simulations, and to calculate the heating and cooling source terms in the MHD equations in flows where radiation pressure is small compared with gas pressure. For the latter case, the module is combined with the standard MHD integrators using operator splitting: we describe this approach in detail, including a new constraint on the time step for stability due to radiation diffusion modes. Implementation of the VET method for radiation pressure dominated flows is described in a companion paper. We present results from a suite of test problems for both the RT solver itself and for dynamical problems that include radiative heating and cooling. These tests demonstrate that the radiative transfer solution is accurate and confirm that the operator split method is stable, convergent, and efficient for problems of interest. We demonstrate there is no need to adopt ad hoc assumptions of questionable accuracy to solve RT problems in concert with MHD: the computational cost for our general-purpose module for simple (e.g., LTE gray) problems can be comparable to or less than a single time step of Athena's MHD integrators, and only few times more expensive than that for more general (non-LTE) problems.« less
NLTE Line Blanketed Model Atmospheres for Hot, Metal-rich White Dwarfs
NASA Astrophysics Data System (ADS)
Hubeny, I.; Lanz, T.
1993-05-01
Recent observations of some hot DA white dwarfs (Feige 24, G191 B2B - Sion et al. 1992, Ap.J. 391, L29; Vennes et al. 1992, Ap.J. 392, L27) and subsequent analyses have demonstrated that their atmospheres are contaminated with heavy metal species with appreciable abundances. So far, modeling was mostly limited to calculating synthetic spectra (usually in LTE), based on previously calculated model atmospheres that were constructed assuming a simplified chemical composition. However, in reality the metal lines may also significantly influence the temperature structure, and consequently the ionization balance of some important species. Since the effective temperature is rather high (55000 to 60000 K), the NLTE effects may be important despite the high gravity. Therefore, in order to settle the question on metal abundances of hot DA white dwarfs, we need to calculate NLTE fully line blanketed model atmospheres. Using our previously developed hybrid complete linearization/accelerated lambda iteration method, we have calculated a set of NLTE models including H, He, C, N, O, and Fe, with some 13000 lines of Fe IV, Fe V and Fe VI taken into account explicitly in model construction. The NLTE departure coefficients for all levels of Fe IV, Fe V, and Fe VI are then employed in the spectrum synthesis program SYNSPEC. In the first part of this study, we present a theoretical comparison between models computed with adding more and more opacity sources, and show how the temperature structure and synthetic spectra develop. We also discuss possible errors arising from using an inconsistent spectrum synthesis (the metals considered only in the spectrum synthesis, not in the model construction). In the second part, we compare the computed UV spectra with with available observations of Feige 24 and G191 B2B, and deduce limits for the iron abundance of these stars.
A beamline systems model for Accelerator-Driven Transmutation Technology (ADTT) facilities
DOE Office of Scientific and Technical Information (OSTI.GOV)
Todd, A.M.M.; Paulson, C.C.; Peacock, M.A.
1995-10-01
A beamline systems code, that is being developed for Accelerator-Driven Transmutation Technology (ADTT) facility trade studies, is described. The overall program is a joint Grumman, G.H. Gillespie Associates (GHGA) and Los Alamos National Laboratory effort. The GHGA Accelerator Systems Model (ASM) has been adopted as the framework on which this effort is based. Relevant accelerator and beam transport models from earlier Grumman systems codes are being adapted to this framework. Preliminary physics and engineering models for each ADTT beamline component have been constructed. Examples noted include a Bridge Coupled Drift Tube Linac (BCDTL) and the accelerator thermal system. A decisionmore » has been made to confine the ASM framework principally to beamline modeling, while detailed target/blanket, balance-of-plant and facility costing analysis will be performed externally. An interfacing external balance-of-plant and facility costing model, which will permit the performance of iterative facility trade studies, is under separate development. An ABC (Accelerator Based Conversion) example is used to highlight the present models and capabilities.« less
A beamline systems model for Accelerator-Driven Transmutation Technology (ADTT) facilities
DOE Office of Scientific and Technical Information (OSTI.GOV)
Todd, Alan M. M.; Paulson, C. C.; Peacock, M. A.
1995-09-15
A beamline systems code, that is being developed for Accelerator-Driven Transmutation Technology (ADTT) facility trade studies, is described. The overall program is a joint Grumman, G. H. Gillespie Associates (GHGA) and Los Alamos National Laboratory effort. The GHGA Accelerator Systems Model (ASM) has been adopted as the framework on which this effort is based. Relevant accelerator and beam transport models from earlier Grumman systems codes are being adapted to this framework. Preliminary physics and engineering models for each ADTT beamline component have been constructed. Examples noted include a Bridge Coupled Drift Tube Linac (BCDTL) and the accelerator thermal system. Amore » decision has been made to confine the ASM framework principally to beamline modeling, while detailed target/blanket, balance-of-plant and facility costing analysis will be performed externally. An interfacing external balance-of-plant and facility costing model, which will permit the performance of iterative facility trade studies, is under separate development. An ABC (Accelerator Based Conversion) example is used to highlight the present models and capabilities.« less
Bresler, S E; Kalinin, V L; Kopylova, Y U; Krivisky, A S; Rybchin, V N; Shelegedin, V N
1975-07-01
The inactivating and mutagenic action of high-energy radiations with different ionizing capacities (gamma-rays, protons, alpha-particles and accelerated ions of 12C and 20Ne) was studied by using coliphages lambda11 and SD as subjects. In particular the role of irradiation conditions (broth suspension, pure buffer, dry samples) and of the host functions recA, exrA and polA was investigated. The dose-response curve of induced mutagenesis was studied by measuring the yield of vir mutants in lambda11 and plaque mutants in SD. The following results were obtained. (1) The inactivation kinetics of phages under the action of gamma-rays and protons was first order to a survival of 10(-7). Heavy ions also showed exponential inactivation kinetics to a survival of 10(-4). At higher doses of 20Ne ion bombardment some deviation from one-hit kinetics was observed. For dry samples of phages the dimensions of targets for all types of radiation were approximately proportional to the molecular weights of phage DNA's. For densely ionizing radiation (heavy ions) the inactivating action was 3-5 times weaker than for gamma-rays and protons. (2) Mutagenesis was observed for all types of radiation, but heavy ions were 1-5-2 times less efficient than gamma-rays. For both phages studied the dose-response curve of mutagenesis was non-linear. The dependence on the dose was near to parabolic for lambda11. For SD a plateau or maximum of mutagenesis was observed for the relative number of mutants at a survival of about 10(-4). (3) Host-cell functions recA and exrA were practically indifferent for survival of gamma-irradiated phage lambda11, but indispensable for mutagenesis. Mutation recAI3 abolished induced vir mutations totally and exrA- reduced them significantly. The absence of the function polA had a considerable influence on phage survival, but no effect on vir mutation yield (if compared at the same survival level). (4) In conditions of indirect action of gamma-rays no vir mutations were induced. This is regarded as evidence that the single-strand breaks formed under indirect action conditions cannot serve as pre-mutational damage in DNA.
Wang, Silun; Wu, Ed X; Qiu, Deqiang; Leung, Lucullus H T; Lau, Ho-Fai; Khong, Pek-Lan
2009-02-01
Radiation-induced white matter (WM) damage is a major side effect of whole brain irradiation among childhood cancer survivors. We evaluate longitudinally the diffusion characteristics of the late radiation-induced WM damage in a rat model after 25 and 30 Gy irradiation to the hemibrain at 8 time points from 2 to 48 weeks postradiation. We hypothesize that diffusion tensor magnetic resonance imaging (DTI) indices including fractional anisotropy (FA), trace, axial diffusivity (lambda(//)), and radial diffusivity (lambda( perpendicular)) can accurately detect and monitor the histopathologic changes of radiation-induced WM damage, measured at the EC, and that these changes are dose and time dependent. Results showed a progressive reduction of FA, which was driven by reduction in lambda(//) from 4 to 40 weeks postradiation, and an increase in lambda( perpendicular) with return to baseline in lambda(//) at 48 weeks postradiation. Histologic evaluation of irradiated WM showed reactive astrogliosis from 4 weeks postradiation with reversal at 36 weeks, and demyelination, axonal degeneration, and necrosis at 48 weeks postradiation. Moreover, changes in lambda(//) correlated with reactive astrogliosis (P < 0.01) and lambda( perpendicular) correlated with demyelination (P < 0.01). Higher radiation dose (30 Gy) induced earlier and more severe histologic changes than lower radiation dose (25 Gy), and these differences were reflected by the magnitude of changes in lambda(//) and lambda( perpendicular). DTI indices reflected the histopathologic changes of WM damage and our results support the use of DTI as a biomarker to noninvasively monitor radiation-induced WM damage.
Abbas, Naeem; Shad, Sarfraz Ali
2015-07-01
Lambda-cyhalothrin, a sodium channel modulator insecticide, has been used frequently for the control of house flies, Musca domestica L. (Diptera: Muscidae) worldwide, including Pakistan. This experiment was performed to determine the selection and assessment of lambda-cyhalothrin resistance evolution along with four other insecticides. After 26 generations of selection, the lambda-cyhalothrin-selected population developed 445-fold resistance to lambda-cyhalothrin compared to the susceptible population. There was low cross-resistance to bifenthrin and very low cross-resistance to methomyl, imidacloprid, and fipronil in the lambda-cyhalothrin-selected population compared to the field population (G1). Realized heritability (h (2)) of resistance to lambda-cyhalothrin, bifenthrin, methomyl, imidacloprid, and fipronil was 0.07, 0.05, 0.01, 0.08, and 0.08, respectively. The projected rate of resistance development revealed that if 90 % house flies were selected, then a tenfold increase in lethal concentration 50 occurred after 17, 20, 159, 13, and 14 generations for lambda-cyhalothrin (h (2) = 0.07, slope = 2.09), bifenthrin (h (2) = 0.05, slope = 1.73), methomyl (h (2) = 0.01, slope = 2.52), imidacloprid (h (2) = 0.08, slope = 1.89), and fipronil (h (2) = 0.08, slope = 2.03), respectively. The results of our study concluded that the house fly has the potential to develop multiple insecticide resistances following continued selection pressure with lambda-cyhalothrin. This study will be helpful for assisting the development of resistance management strategies.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Yuan, Fuping; Wu, Xiaolei
2013-05-28
A series of large-scale molecular dynamics simulations have been performed to investigate the tensile properties of nanotwinned (NT) copper with hierarchically twinned structures (HTS). For the same grain size d and the same spacing of primary twins {lambda}{sub 1}, the average flow stress first increases as the spacing of secondary twins {lambda}{sub 2} decreases, reaching a maximum at a critical {lambda}{sub 2}, and then decreases as {lambda}{sub 2} becomes even smaller. The smaller the spacing for {lambda}{sub 1}, the smaller the critical spacing for {lambda}{sub 2}. There exists a transition in dominating deformation mechanisms, occurring at a critical spacing ofmore » {lambda}{sub 2} for which strength is maximized. Above the critical spacing of {lambda}{sub 2}, the deformation mechanisms are dominated by the two Hall-Petch type strengthening mechanisms: (a) partial dislocations emitted from grain boundaries (GBs) travel across other GBs and twin boundaries (TBs); (b) partial dislocations emitted from TBs travel across other TBs. Below the critical spacing of {lambda}{sub 2}, the deformation mechanism is dominated by the two softening mechanisms: (a) Partial dislocations emitted from boundaries of the primary twins travel parallel to the TBs of the secondary twins, leading to detwinning of the secondary twins; (b) Boundaries of the primary twins shift entirely, leading to thickening in one part of primary twins and thinning in the other part of primary twins. The present results should provide insights to design the microstructures for reinforcing the mechanical properties in the NT metals with HTS.« less
RECONCILIATION OF WAITING TIME STATISTICS OF SOLAR FLARES OBSERVED IN HARD X-RAYS
DOE Office of Scientific and Technical Information (OSTI.GOV)
Aschwanden, Markus J.; McTiernan, James M., E-mail: aschwanden@lmsal.co, E-mail: jimm@ssl.berkeley.ed
2010-07-10
We study the waiting time distributions of solar flares observed in hard X-rays with ISEE-3/ICE, HXRBS/SMM, WATCH/GRANAT, BATSE/CGRO, and RHESSI. Although discordant results and interpretations have been published earlier, based on relatively small ranges (<2 decades) of waiting times, we find that all observed distributions, spanning over 6 decades of waiting times ({Delta}t {approx} 10{sup -3}-10{sup 3} hr), can be reconciled with a single distribution function, N({Delta}t) {proportional_to} {lambda}{sub 0}(1 + {lambda}{sub 0{Delta}}t){sup -2}, which has a power-law slope of p {approx} 2.0 at large waiting times ({Delta}t {approx} 1-1000 hr) and flattens out at short waiting times {Delta}t {approx}
Alternatives to Goodman and Kruskal's Lambda.
ERIC Educational Resources Information Center
Stavig, Gordon R.
1979-01-01
Lambda and kappa coefficients of nominal scale association are developed for research hypotheses that involve predictions of modality, agreement, or some theoretically specified configuration. The proposed new coefficient is offered as an alternative to Goodman and Kruskal's lambda. (Author/CTM)
Hepatopancreatic intoxication of lambda cyhalothrin insecticide on albino rats
Elhalwagy, Manal EA; Abd-Alrahman, Sherif H; Nahas, AA; Ziada, Reem M; Mohamady, Aziza H
2015-01-01
Background: Despite the known adverse effects of lambda cyhalothrin insecticide, little is known about its hepatopancreatic intoxication effects. The present study was carried out to elucidate sub-chronic effect of Karat 2.5% EC formulation of lambda cyhalothrin on male albino rats. Methods: To explore the effects of exposure to lambda cyhalothrin on rats and its mechanism, low (1/40 of LD50, 5 mg/kg/day) and high dose (1/4 of LD50, 50 mg/kg/day) lambda cyhalothrin were applied to rats via drinking water for 3 months. Blood samples were collected monthly, and the animals were dissected for liver and pancreas’s examination at the end of the experiment. Lambda cyhalothrin administration was associated with the elevation in lipid peroxidation marker, malondialdehyde (MDA), reduction in SH-protein a major marker for antioxidant, as well as basel paraoxonase (PON) in both treated groups throughout the experimental periods. Results: In addition, significant elevations in liver enzymes alanin amino transferase, (ALT), and aspartate amino transferase (AST), as well as plasma acetylcholinesterase (AChE) and glucose level. While, significant reduction in insulin level through the experimental periods. Results of histopathological and histochemical studies showed that lambda cyhalothrin exposure induces liver and pancreatic tissues damage and depletion in glycogen content was pronounced in liver of both treated groups. Conclusions: In conclusion subchronic intoxication with lambda cyhalothrin formulation induced remarkable changes in the examined parameters. PMID:26221269
Hepatopancreatic intoxication of lambda cyhalothrin insecticide on albino rats.
Elhalwagy, Manal Ea; Abd-Alrahman, Sherif H; Nahas, A A; Ziada, Reem M; Mohamady, Aziza H
2015-01-01
Despite the known adverse effects of lambda cyhalothrin insecticide, little is known about its hepatopancreatic intoxication effects. The present study was carried out to elucidate sub-chronic effect of Karat 2.5% EC formulation of lambda cyhalothrin on male albino rats. To explore the effects of exposure to lambda cyhalothrin on rats and its mechanism, low (1/40 of LD50, 5 mg/kg/day) and high dose (1/4 of LD50, 50 mg/kg/day) lambda cyhalothrin were applied to rats via drinking water for 3 months. Blood samples were collected monthly, and the animals were dissected for liver and pancreas's examination at the end of the experiment. Lambda cyhalothrin administration was associated with the elevation in lipid peroxidation marker, malondialdehyde (MDA), reduction in SH-protein a major marker for antioxidant, as well as basel paraoxonase (PON) in both treated groups throughout the experimental periods. In addition, significant elevations in liver enzymes alanin amino transferase, (ALT), and aspartate amino transferase (AST), as well as plasma acetylcholinesterase (AChE) and glucose level. While, significant reduction in insulin level through the experimental periods. Results of histopathological and histochemical studies showed that lambda cyhalothrin exposure induces liver and pancreatic tissues damage and depletion in glycogen content was pronounced in liver of both treated groups. In conclusion subchronic intoxication with lambda cyhalothrin formulation induced remarkable changes in the examined parameters.
Anisotropy of the penetration depth in La2-xSrxCuO4 in underdoped and overdoped regions
NASA Astrophysics Data System (ADS)
Zaleski, A. J.; Klamut, J.
1999-12-01
We present the results of measurements of the penetration depth anisotropy in pulverized, ceramic La2-xSrxCuO4. The measurements were carried out for x = 0.08, 0.1, 0.125, 0.15 and 0.2. The powdered samples, immersed in wax, were magnetically oriented in a static magnetic field of 10 T. The penetration depth in the a-b plane, icons/Journals/Common/lambda" ALT="lambda" ALIGN="TOP"/>ab, and perpendicular to it, icons/Journals/Common/lambda" ALT="lambda" ALIGN="TOP"/>icons/Journals/Common/perp" ALT="perp" ALIGN="MIDDLE"/>, were derived from alternating-current susceptibility measurements. For underdoped samples they both vary linearly with temperature (for the low-temperature region), while for the samples from the overdoped region the measured points can be fitted by an exponential function. These results support Uemura's picture (Uemura Y J 1997 Physica C 282-287 194) of crossover from Bose-Einstein condensation to a Bardeen-Cooper-Schrieffer mechanism of superconductivity. The penetration depth values extrapolated to T = 0 may be described by a quadratic function of the strontium concentration (for both icons/Journals/Common/lambda" ALT="lambda" ALIGN="TOP"/>ab and icons/Journals/Common/lambda" ALT="lambda" ALIGN="TOP"/>icons/Journals/Common/perp" ALT="perp" ALIGN="MIDDLE"/>). The anisotropy of the penetration depth as a function of the substitution shows a similar dependence to the critical temperature Tc(x).
Iterative methods for 3D implicit finite-difference migration using the complex Padé approximation
NASA Astrophysics Data System (ADS)
Costa, Carlos A. N.; Campos, Itamara S.; Costa, Jessé C.; Neto, Francisco A.; Schleicher, Jörg; Novais, Amélia
2013-08-01
Conventional implementations of 3D finite-difference (FD) migration use splitting techniques to accelerate performance and save computational cost. However, such techniques are plagued with numerical anisotropy that jeopardises the correct positioning of dipping reflectors in the directions not used for the operator splitting. We implement 3D downward continuation FD migration without splitting using a complex Padé approximation. In this way, the numerical anisotropy is eliminated at the expense of a computationally more intensive solution of a large-band linear system. We compare the performance of the iterative stabilized biconjugate gradient (BICGSTAB) and that of the multifrontal massively parallel direct solver (MUMPS). It turns out that the use of the complex Padé approximation not only stabilizes the solution, but also acts as an effective preconditioner for the BICGSTAB algorithm, reducing the number of iterations as compared to the implementation using the real Padé expansion. As a consequence, the iterative BICGSTAB method is more efficient than the direct MUMPS method when solving a single term in the Padé expansion. The results of both algorithms, here evaluated by computing the migration impulse response in the SEG/EAGE salt model, are of comparable quality.
Iterative Nonlinear Tikhonov Algorithm with Constraints for Electromagnetic Tomography
NASA Technical Reports Server (NTRS)
Xu, Feng; Deshpande, Manohar
2012-01-01
Low frequency electromagnetic tomography such as the capacitance tomography (ECT) has been proposed for monitoring and mass-gauging of gas-liquid two-phase system under microgravity condition in NASA's future long-term space missions. Due to the ill-posed inverse problem of ECT, images reconstructed using conventional linear algorithms often suffer from limitations such as low resolution and blurred edges. Hence, new efficient high resolution nonlinear imaging algorithms are needed for accurate two-phase imaging. The proposed Iterative Nonlinear Tikhonov Regularized Algorithm with Constraints (INTAC) is based on an efficient finite element method (FEM) forward model of quasi-static electromagnetic problem. It iteratively minimizes the discrepancy between FEM simulated and actual measured capacitances by adjusting the reconstructed image using the Tikhonov regularized method. More importantly, it enforces the known permittivity of two phases to the unknown pixels which exceed the reasonable range of permittivity in each iteration. This strategy does not only stabilize the converging process, but also produces sharper images. Simulations show that resolution improvement of over 2 times can be achieved by INTAC with respect to conventional approaches. Strategies to further improve spatial imaging resolution are suggested, as well as techniques to accelerate nonlinear forward model and thus increase the temporal resolution.
Maruotti, G M; Saccone, G; Morlando, M; Martinelli, P
2016-07-01
To evaluate the accuracy of first-trimester sonographic determination of chorionicity in twin gestations using the lambda sign. Electronic databases (MEDLINE, PROSPERO, Scopus, ClinicalTrials.gov, EMBASE, Sciencedirect) were searched from their inception until April 2016. We included only study assessing the accuracy lambda sign in prediction of monochorionicity in the first trimester. Forest plots for pooled sensitivity and specificity with 95% confidence intervals (CI) were generated. In addition, symmetric summary receiver-operating characteristic curves were plotted. The area under the curve (AUC) was also computed to evaluate the overall accuracy of the diagnostic test. Nine studies, including 2292 twins, were analysed. In all of these studies, identification of the lambda sign was used to diagnose chorionicity on real-time B-mode imaging. Twins were classified as monochorionic if there was a single placental mass in the absence of the lambda sign, and dichorionic if there was a single placental mass but the lambda sign was present or the placentas were not adjacent to each other. In all nine studies, placental histology or discordant fetal sex were used to confirm chorionicity. Pooled results from the meta-analysis showed that sensitivity of the presence of the lambda sign in the prediction of dichorionicity was 99% (95% CI 98-100%), and specificity was 95% (95% CI 92-97%). Pooled sensitivity of the absence of the lambda sign in the prediction of monochorionicity was 96% (95% CI 92-98%) and pooled specificity was 99% (95% CI 98-99%). The AUC for diagnostic accuracy was 0.99, and suggested very high diagnostic accuracy. The lambda sign predicts chorionicity with a high degree of accuracy before 14 weeks of gestation. Presence of the lambda sign indicates dichorionicity, and absence of the lambda sign indicates monochorionicity. All hospitals should encourage departments providing ultrasound services to determine chorionicity when examining women with twin pregnancies in the first trimester. As determination of chorionicity is most accurate before 14 weeks when the amnion and chorion have not yet fused, the first-trimester scan in twin pregnancy is paramount. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.
Simultaneous X-ray, UV, and Optical Variations in lambda ERI (B2e)
NASA Astrophysics Data System (ADS)
Smith, M. A.; Murakami, T.; Anandarao, B.
1996-12-01
We have carried out a simultaneous observing campaign on the prototypical Be star lambda Eri using ground stations and ROSAT, ASCA, IUE, and Voyager spacecrafts during the week of February-March 1995; a smaller campaign was carried out the following September. In late February lambda Eri showed extraordinary disk-wind activity. ROSAT/HRI monitoring disclosed no large flares such as ROSAT observed in 1991 in lambda Eri. Possible low amplitude fluctuations in the 1995 data occurred at the same time with unusual activity in Hα , HeI lambda 6678, HeII lambda 1640, CIII, and the CIV doublet. The helium line activity suggests that mass ejection occurred at the base of the wind. The strong CIII and CIV lines implies that shock interactions originated in the wind flow. It is not clear that the X-ray fluctuations are directly related to the increases in wind line absorption. Within hours of the mild X-ray flux variations found by ROSAT on February 28, the Voyager UVS observed a ``ringing" that decayed over three 3-hr. cycles. The amplitude of these fluctuations was large (50%) at lambda lambda 950-1100, decreased rapidly with wavelength, and faded to nondetection above lambda 1300. Various considerations indicate that these continuum variations were not due to an instrument pathology in the UVS. Rather, they appear to be due to a time-dependent flux deficit in the lambda lambda 1250 during the minima of these cycles. We outline a scenario in which dense plasma over the star's surface is alternately heated and cooled quasi-periodically to produce the flux changes. Additional examples of this new phenomenon are needed. Amateur astronomers can make a significant contribution to the understanding of flickering in Be star light curves during their outburst phases. We also draw attention to an increase in the emission of the Hα line that occurred at about the same time the FUV ringing started. This increased emission hints that ~ 50,000K plasma near the star's surface can infuence the circumstellar disc some distance away by its increased Lyman continuum flux.
Improvement of voltage holding and high current beam acceleration by MeV accelerator for ITER NB
DOE Office of Scientific and Technical Information (OSTI.GOV)
Taniguchi, M.; Kashiwagi, M.; Inoue, T.
Voltage holding of -1 MV is an essential issue in development of a multi-aperture multi-grid (MAMuG) negative ion accelerator, of which target is to accelerate 200 A/m{sup 2} H{sup -} ion beam up to the energy of 1 MeV for several tens seconds. Review of voltage holding results ever obtained with various geometries of the accelerators showed that the voltage holding capability was about a half of designed value based on the experiment obtained from ideal small electrode. This is considered due to local electric field concentration in the accelerators, such as edge and steps between multi-aperture grids and itsmore » support structures. Based on the detailed investigation with electric field analysis, accelerator was modified to reduce the electric field concentration by reshaping the support structures and expanding the gap length between the grid supports. After the modifications, the accelerator succeeded in sustaining -1 MV for more than one hour in vacuum. Improvement of the voltage holding characteristics progressed the energy and current accelerated by the MeV accelerator. Up to 2010, beam parameters achieved by the MAMuG accelerator were increased to 879 keV, 0.36 A (157 A/m{sup 2}) at perveance matched condition and 937 keV, 0.33 A (144 A/m{sup 2}) slightly under perveance.« less
Waggoner, B T; Marrs, C F; Howe, M M; Pato, M L
1984-07-15
The regions of bacteriophage Mu involved in host cell killing were determined by infection of a lambda-immune host with 12 lambda pMu-transducing phages carrying different amounts of Mu DNA beginning at the left end. Infecting lambda pMu phages containing 5.0 (+/- 0.2) kb or less of the left end of Mu DNA did not kill the lambda-immune host, whereas lambda pMu containing 5.1 kb did kill, thus locating the right end of the kil gene between approximately 5.0 and 5.1 kb. For the Kil+ phages the extent of killing increased as the multiplicity of infection (m.o.i.) increased. In addition, killing was also affected by the presence of at least two other regions of Mu DNA: one, located between 5.1 and 5.8 kb, decreased the extent of killing; the other, located between 6.3 and 7.9 kb, greatly increased host cell killing. Killing was also assayed after lambda pMu infection of a lambda-immune host carrying a mini-Mu deleted for most of the B gene and the middle region of Mu DNA. Complementation of mini-Mu replication by infecting B+ lambda pMu phages resulted in killing of the lambda-immune, mini-Mu-containing host, regardless of the presence or absence of the Mu kil gene. The extent of host cell killing increased as the m.o.i. of the infecting lambda pMu increased, and was further enhanced by both the presence of the kil gene and the region located between 6.3 and 7.9 kb. These distinct processes of kil-mediated killing in the absence of replication and non-kil-mediated killing in the presence of replication were also observed after induction of replication-deficient and kil mutant prophages, respectively.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Albertus, C.; Nieves, J.; Hernandez, E.
We present results for the strong widths corresponding to the {sigma}{sub c}{yields}{lambda}{sub c}{pi}, {sigma}{sub c}*{yields}{lambda}{sub c}{pi} and {xi}{sub c}*{yields}{xi}{sub c}{pi} decays. The calculations have been done in a nonrelativistic constituent quark model with wave functions that take advantage of the constraints imposed by heavy quark symmetry. Partial conservation of axial current hypothesis allows us to determine the strong vertices from an analysis of the axial current matrix elements. Our results {gamma}({sigma}{sub c}{sup ++}{yields}{lambda}{sub c}{sup +}{pi}{sup +})=2.41{+-}0.07{+-}0.02 MeV, {gamma}({sigma}{sub c}{sup +}{yields}{lambda}{sub c}{sup +}{pi}{sup 0})=2.79{+-}0.08{+-}0.02 MeV, {gamma}({sigma}{sub c}{sup 0}{yields}{lambda}{sub c}{sup +}{pi}{sup -})=2.37{+-}0.07{+-}0.02 MeV, {gamma}({sigma}{sub c}*{sup ++}{yields}{lambda}{sub c}{sup +}{pi}{sup +})=17.52{+-}0.74{+-}0.12 MeV, {gamma}({sigma}{sub c}*{supmore » +}{yields}{lambda}{sub c}{sup +}{pi}{sup 0})=17.31{+-}0.73{+-}0.12 MeV, {gamma}({sigma}{sub c}*{sup 0}{yields}{lambda}{sub c}{sup +}{pi}{sup -})=16.90{+-}0.71{+-}0.12 MeV, {gamma}({xi}{sub c}*{sup +}{yields}{xi}{sub c}{sup 0}{pi}{sup +}+{xi}{sub c}{sup +}{pi}{sup 0})=3.18{+-}0.10{+-}0.01 MeV, and {gamma}({xi}{sub c}*{sup 0}{yields}{xi}{sub c}{sup +}{pi}{sup -}+{xi}{sub c}{sup 0}{pi}{sup 0})=3.03{+-}0.10{+-}0.01 MeV are in good agreement with experimental determinations.« less
NASA Astrophysics Data System (ADS)
Franzen, P.; Gutser, R.; Fantz, U.; Kraus, W.; Falter, H.; Fröschle, M.; Heinemann, B.; McNeely, P.; Nocentini, R.; Riedl, R.; Stäbler, A.; Wünderlich, D.
2011-07-01
The ITER neutral beam system requires a negative hydrogen ion beam of 48 A with an energy of 0.87 MeV, and a negative deuterium beam of 40 A with an energy of 1 MeV. The beam is extracted from a large ion source of dimension 1.9 × 0.9 m2 by an acceleration system consisting of seven grids with 1280 apertures each. Currently, apertures with a diameter of 14 mm in the first grid are foreseen. In 2007, the IPP RF source was chosen as the ITER reference source due to its reduced maintenance compared with arc-driven sources and the successful development at the BATMAN test facility of being equipped with the small IPP prototype RF source ( {\\sim}\\frac{1}{8} of the area of the ITER NBI source). These results, however, were obtained with an extraction system with 8 mm diameter apertures. This paper reports on the comparison of the source performance at BATMAN of an ITER-relevant extraction system equipped with chamfered apertures with a 14 mm diameter and 8 mm diameter aperture extraction system. The most important result is that there is almost no difference in the achieved current density—being consistent with ion trajectory calculations—and the amount of co-extracted electrons. Furthermore, some aspects of the beam optics of both extraction systems are discussed.
Modified van Vaals-Bergman coaxial cable coil (lambda coil) for high-field imaging.
Matsuzawa, H; Nakada, T
1996-03-01
An easily constructed, low-capacitive coupling volume coil based on the van Vaals-Bergman coaxial cable coil for high field imaging is described. The coil (designated "lambda coil") was constructed using two 5/4 length 50 omega coaxial cables matched to a 50 omega transmission line with LC bridge balun. The standing wave on the single 5/4 lambda length coaxial cable provides two points of current maxima in oppositional direction. Therefore, the four current elements necessary for effective B1 field generation can be obtained by two 5/4 lambda length coaxial cables arranged analogous to 1/2 lambda T-antenna. Capacitive coupling between the coil elements and conductive samples (i.e. animals) is minimized by simply retaining the shield of the coaxial cable for the area of voltage maxima. The lambda coil exhibited excellent performance as a volume coil with a high quality factor and highly homogeneous rf fields. Because of its dramatically simple architecture and excellent performance, the lambda coil configuration appears to be an economical alternative to the original van Vaals-Bergman design, especially for research facilities with a high field magnet and limited bore space.
Wind and boundary layers in Rayleigh-Bénard convection. II. Boundary layer character and scaling.
van Reeuwijk, Maarten; Jonker, Harm J J; Hanjalić, Kemo
2008-03-01
The scaling of the kinematic boundary layer thickness lambda(u) and the friction factor C(f) at the top and bottom walls of Rayleigh-Bénard convection is studied by direct numerical simulation (DNS). By a detailed analysis of the friction factor, a new parameterisation for C(f) and lambda(u) is proposed. The simulations were made of an L/H=4 aspect-ratio domain with periodic lateral boundary conditions at Ra=(10(5), 10(6), 10(7), 10(8)) and Pr=1. The continuous spectrum, as well as significant forcing due to Reynolds stresses, clearly indicates a turbulent character of the boundary layer, while viscous effects cannot be neglected, judging from the scaling of classical integral boundary layer parameters with Reynolds number. Using a conceptual wind model, we find that the friction factor C(f) should scale proportionally to the thermal boundary layer thickness as C(f) proportional variant lambda(Theta)/H, while the kinetic boundary layer thickness lambda(u) scales inversely proportionally to the thermal boundary layer thickness and wind Reynolds number lambda(u)/H proportional variant (lambda(Theta)/H)(-1)Re(-1). The predicted trends for C(f) and lambda(u) are in agreement with DNS results.
Piner, Petek; Üner, Nevin
2014-11-01
The objective of this research was to investigate the neurotoxic effects of pyrethroid pesticide lambda-cyhalothrin by the modulation of cytochrome P450 with piperonyl butoxide in the brain of juvenile Oreochromis niloticus. The fish were exposed to 0.48 μg L(-1) (1/6 of the 96-h LC50 ) lambda-cyhalothrin and 10 μg L(-1) piperonyl butoxide for 96 h and 15 days. tGSH, GSSG, TBARS contents, GPx, GR, GST, and AChE enzymes activities were determined by spectrophotometrical methods and Hsp70 content was analyzed by ELISA technique. Lambda-cyhalothrin had no significant effect on the components of GSH redox system, lipid peroxidation and Hsp70 levels but inhibited AChE activity. In the presence of piperonyl butoxide, lambda-cyhalothrin caused increases in tGSH, GSSG, TBARS and Hsp70 contents, GST activity, and decrease in AChE activity. Present results showed that in the presence of piperonyl butoxide, lambda-cyhalothrin caused neurotoxic effects by increasing oxidative stress. Adaptation to its oxidative stress effects may be supplied by GSH-related antioxidant system. Piperonyl butoxide revealed neurotoxic effect of lambda-cyhalothrin. Copyright © 2013 Wiley Periodicals, Inc., a Wiley company.
Preliminary use of nematic liquid crystal adaptive optics with a 2.16-meter reflecting telescope.
Cao, Zhaoliang; Mu, Quanquan; Hu, Lifa; Li, Dayu; Peng, Zenghui; Liu, Yonggang; Xuan, Li
2009-02-16
A nematic liquid crystal adaptive optics system (NLC AOS) was assembled for a 2.16-m telescope to correct for atmospheric turbulence. LC AOS was designed and optimized with Zemax optical software. Second, an adaptive correction experiment was performed in the laboratory to test the performance of the NLC AOS. After the correction, the peak to valley (PV) and root mean square (RMS) of the wavefront were down to 0.2 lambda (lambda=633 nm) and 0.05 lambda, respectively. Finally, the star of Pollux (beta Gem) was tracked using the 2.16-m Reflecting Telescope, and real time correction of the atmospheric turbulence was performed with the NLC AOS. After the adaptive correction, the average PV and RMS of the wavefront were reduced from 11 lambda and 2.5 lambda to 2.3 lambda and 0.6 lambda, respectively. Although the intensity distribution of the beta Gem was converged and its peak was sharp, a halo still existed around the peak. These results indicated that the NLC AOS only partially corrected the vertical atmospheric turbulence. The limitations of our NLC AOS are discussed and some proposals are made.
NASA Astrophysics Data System (ADS)
Citro, V.; Luchini, P.; Giannetti, F.; Auteri, F.
2017-09-01
The study of the stability of a dynamical system described by a set of partial differential equations (PDEs) requires the computation of unstable states as the control parameter exceeds its critical threshold. Unfortunately, the discretization of the governing equations, especially for fluid dynamic applications, often leads to very large discrete systems. As a consequence, matrix based methods, like for example the Newton-Raphson algorithm coupled with a direct inversion of the Jacobian matrix, lead to computational costs too large in terms of both memory and execution time. We present a novel iterative algorithm, inspired by Krylov-subspace methods, which is able to compute unstable steady states and/or accelerate the convergence to stable configurations. Our new algorithm is based on the minimization of the residual norm at each iteration step with a projection basis updated at each iteration rather than at periodic restarts like in the classical GMRES method. The algorithm is able to stabilize any dynamical system without increasing the computational time of the original numerical procedure used to solve the governing equations. Moreover, it can be easily inserted into a pre-existing relaxation (integration) procedure with a call to a single black-box subroutine. The procedure is discussed for problems of different sizes, ranging from a small two-dimensional system to a large three-dimensional problem involving the Navier-Stokes equations. We show that the proposed algorithm is able to improve the convergence of existing iterative schemes. In particular, the procedure is applied to the subcritical flow inside a lid-driven cavity. We also discuss the application of Boostconv to compute the unstable steady flow past a fixed circular cylinder (2D) and boundary-layer flow over a hemispherical roughness element (3D) for supercritical values of the Reynolds number. We show that Boostconv can be used effectively with any spatial discretization, be it a finite-difference, finite-volume, finite-element or spectral method.
Effects of ELMs on ITER divertor armour materials
NASA Astrophysics Data System (ADS)
Zhitlukhin, A.; Klimov, N.; Landman, I.; Linke, J.; Loarte, A.; Merola, M.; Podkovyrov, V.; Federici, G.; Bazylev, B.; Pestchanyi, S.; Safronov, V.; Hirai, T.; Maynashev, V.; Levashov, V.; Muzichenko, A.
2007-06-01
This paper is concerned with investigation of an erosion of the ITER-like divertor plasma facing components under plasma heat loads expected during the Type I ELMs in ITER. These experiments were carried out on plasma accelerator QSPA at the SRC RF TRINITI under EU/RF collaboration. Targets were exposed by series repeated plasma pulses with heat loads in a range of 0.5-1.5 MJ/m2 and pulse duration 0.5 ms. Erosion of CFC macrobrushes was determined mainly by sublimation of PAN-fibres that was less than 2.5 μm per pulse. The CFC erosion was negligible at the energy density less than 0.5 MJ/m2 and was increased to the average value 0.3 μm per pulse at 1.5 MJ/m2. The pure tungsten macrobrushes erosion was small in the energy range of 0.5-1.3 MJ/m2. The sharp growth of tungsten erosion and the intense droplet ejection were observed at the energy density of 1.5 MJ/m2.
Numerical evaluation of mobile robot navigation in static indoor environment via EGAOR Iteration
NASA Astrophysics Data System (ADS)
Dahalan, A. A.; Saudi, A.; Sulaiman, J.; Din, W. R. W.
2017-09-01
One of the key issues in mobile robot navigation is the ability for the robot to move from an arbitrary start location to a specified goal location without colliding with any obstacles while traveling, also known as mobile robot path planning problem. In this paper, however, we examined the performance of a robust searching algorithm that relies on the use of harmonic potentials of the environment to generate smooth and safe path for mobile robot navigation in a static known indoor environment. The harmonic potentials will be discretized by using Laplacian’s operator to form a system of algebraic approximation equations. This algebraic linear system will be computed via 4-Point Explicit Group Accelerated Over-Relaxation (4-EGAOR) iterative method for rapid computation. The performance of the proposed algorithm will then be compared and analyzed against the existing algorithms in terms of number of iterations and execution time. The result shows that the proposed algorithm performed better than the existing methods.
Analysis and Design of ITER 1 MV Core Snubber
NASA Astrophysics Data System (ADS)
Wang, Haitian; Li, Ge
2012-11-01
The core snubber, as a passive protection device, can suppress arc current and absorb stored energy in stray capacitance during the electrical breakdown in accelerating electrodes of ITER NBI. In order to design the core snubber of ITER, the control parameters of the arc peak current have been firstly analyzed by the Fink-Baker-Owren (FBO) method, which are used for designing the DIIID 100 kV snubber. The B-H curve can be derived from the measured voltage and current waveforms, and the hysteresis loss of the core snubber can be derived using the revised parallelogram method. The core snubber can be a simplified representation as an equivalent parallel resistance and inductance, which has been neglected by the FBO method. A simulation code including the parallel equivalent resistance and inductance has been set up. The simulation and experiments result in dramatically large arc shorting currents due to the parallel inductance effect. The case shows that the core snubber utilizing the FBO method gives more compact design.
Generalized conjugate-gradient methods for the Navier-Stokes equations
NASA Technical Reports Server (NTRS)
Ajmani, Kumud; Ng, Wing-Fai; Liou, Meng-Sing
1991-01-01
A generalized conjugate-gradient method is used to solve the two-dimensional, compressible Navier-Stokes equations of fluid flow. The equations are discretized with an implicit, upwind finite-volume formulation. Preconditioning techniques are incorporated into the new solver to accelerate convergence of the overall iterative method. The superiority of the new solver is demonstrated by comparisons with a conventional line Gauss-Siedel Relaxation solver. Computational test results for transonic flow (trailing edge flow in a transonic turbine cascade) and hypersonic flow (M = 6.0 shock-on-shock phenoena on a cylindrical leading edge) are presented. When applied to the transonic cascade case, the new solver is 4.4 times faster in terms of number of iterations and 3.1 times faster in terms of CPU time than the Relaxation solver. For the hypersonic shock case, the new solver is 3.0 times faster in terms of number of iterations and 2.2 times faster in terms of CPU time than the Relaxation solver.
NASA Astrophysics Data System (ADS)
Pua, Rizza; Park, Miran; Wi, Sunhee; Cho, Seungryong
2016-12-01
We propose a hybrid metal artifact reduction (MAR) approach for computed tomography (CT) that is computationally more efficient than a fully iterative reconstruction method, but at the same time achieves superior image quality to the interpolation-based in-painting techniques. Our proposed MAR method, an image-based artifact subtraction approach, utilizes an intermediate prior image reconstructed via PDART to recover the background information underlying the high density objects. For comparison, prior images generated by total-variation minimization (TVM) algorithm, as a realization of fully iterative approach, were also utilized as intermediate images. From the simulation and real experimental results, it has been shown that PDART drastically accelerates the reconstruction to an acceptable quality of prior images. Incorporating PDART-reconstructed prior images in the proposed MAR scheme achieved higher quality images than those by a conventional in-painting method. Furthermore, the results were comparable to the fully iterative MAR that uses high-quality TVM prior images.
Solving radiative transfer with line overlaps using Gauss-Seidel algorithms
NASA Astrophysics Data System (ADS)
Daniel, F.; Cernicharo, J.
2008-09-01
Context: The improvement in observational facilities requires refining the modelling of the geometrical structures of astrophysical objects. Nevertheless, for complex problems such as line overlap in molecules showing hyperfine structure, a detailed analysis still requires a large amount of computing time and thus, misinterpretation cannot be dismissed due to an undersampling of the whole space of parameters. Aims: We extend the discussion of the implementation of the Gauss-Seidel algorithm in spherical geometry and include the case of hyperfine line overlap. Methods: We first review the basics of the short characteristics method that is used to solve the radiative transfer equations. Details are given on the determination of the Lambda operator in spherical geometry. The Gauss-Seidel algorithm is then described and, by analogy to the plan-parallel case, we see how to introduce it in spherical geometry. Doing so requires some approximations in order to keep the algorithm competitive. Finally, line overlap effects are included. Results: The convergence speed of the algorithm is compared to the usual Jacobi iterative schemes. The gain in the number of iterations is typically factors of 2 and 4 for the two implementations made of the Gauss-Seidel algorithm. This is obtained despite the introduction of approximations in the algorithm. A comparison of results obtained with and without line overlaps for N2H^+, HCN, and HNC shows that the J=3-2 line intensities are significantly underestimated in models where line overlap is neglected.
Effects of tag loss on direct estimates of population growth rate
Rotella, J.J.; Hines, J.E.
2005-01-01
The temporal symmetry approach of R. Pradel can be used with capture-recapture data to produce retrospective estimates of a population's growth rate, lambda(i), and the relative contributions to lambda(i) from different components of the population. Direct estimation of lambda(i) provides an alternative to using population projection matrices to estimate asymptotic lambda and is seeing increased use. However, the robustness of direct estimates of lambda(1) to violations of several key assumptions has not yet been investigated. Here, we consider tag loss as a possible source of bias for scenarios in which the rate of tag loss is (1) the same for all marked animals in the population and (2) a function of tag age. We computed analytic approximations of the expected values for each of the parameter estimators involved in direct estimation and used those values to calculate bias and precision for each parameter estimator. Estimates of lambda(i) were robust to homogeneous rates of tag loss. When tag loss rates varied by tag age, bias occurred for some of the sampling situations evaluated, especially those with low capture probability, a high rate of tag loss, or both. For situations with low rates of tag loss and high capture probability, bias was low and often negligible. Estimates of contributions of demographic components to lambda(i) were not robust to tag loss. Tag loss reduced the precision of all estimates because tag loss results in fewer marked animals remaining available for estimation. Clearly tag loss should be prevented if possible, and should be considered in analyses of lambda(i), but tag loss does not necessarily preclude unbiased estimation of lambda(i).
Ansari, Reyaz W; Shukla, Rajendra K; Yadav, Rajesh S; Seth, Kavita; Pant, Aditya B; Singh, Dhirendra; Agrawal, Ashok K; Islam, Fakhrul; Khanna, Vinay K
2012-11-01
This study is focused on understanding the mechanism of neurobehavioral toxicity of lambda-cyhalothrin, a new generation type II synthetic pyrethroid in developing rats following their exposure from post-lactational day (PLD)22 to PLD49 and investigate whether neurobehavioral alterations are transient or persistent. Post-lactational exposure to lambda-cyhalothrin (1.0 or 3.0 mg/kg body weight, p.o.) affected grip strength and learning activity in rats on PLD50 and the persistent impairment of grip strength and learning was observed at 15 days after withdrawal of exposure on PLD65. A decrease in the binding of muscarinic-cholinergic receptors in frontocortical, hippocampal, and cerebellar membranes associated with decreased expression of choline acetyltransferase (ChAT) and acetylcholinesterase (AChE) in hippocampus was observed following exposure to lambda-cyhalothrin on PLD50 and PLD65. Exposure to lambda-cyhalothrin was also found to increase the expression of growth-associated protein-43 in hippocampus of rats on PLD50 and PLD65 as compared to controls. A significant increase in lipid peroxidation and protein carbonyl levels and decreased levels of reduced glutathione and activity of superoxide dismutase, catalase, and glutathione peroxidase in brain regions of lambda-cyhalothrin exposed rats were distinctly observed indicating increased oxidative stress. Inhibition of ChAT and AChE activity may cause down-regulation of muscarinic-cholinergic receptors consequently impairing learning activity in developing rats exposed to lambda-cyhalothrin. The data further indicate that long-term exposure to lambda-cyhalothrin at low doses may be detrimental and changes in selected behavioral and neurochemical end points may persist if exposure to lambda-cyhalothrin continues.
Bacteriophage lambda: early pioneer and still relevant
Casjens, Sherwood R.; Hendrix, Roger W.
2015-01-01
Molecular genetic research on bacteriophage lambda carried out during its golden age from the mid 1950's to mid 1980's was critically important in the attainment of our current understanding of the sophisticated and complex mechanisms by which the expression of genes is controlled, of DNA virus assembly and of the molecular nature of lysogeny. The development of molecular cloning techniques, ironically instigated largely by phage lambda researchers, allowed many phage workers to switch their efforts to other biological systems. Nonetheless, since that time the ongoing study of lambda and its relatives have continued to give important new insights. In this review we give some relevant early history and describe recent developments in understanding the molecular biology of lambda's life cycle. PMID:25742714
Development of a Tritium Extruder for ITER Pellet Injection
DOE Office of Scientific and Technical Information (OSTI.GOV)
M.J. Gouge; P.W. Fisher
As part of the International Thermonuclear Experimental Reactor (ITER) plasma fueling development program, Oak Ridge National Laboratory (ORNL) has fabricated a pellet injection system to test the mechanical and thermal properties of extruded tritium. Hydrogenic pellets will be used in ITER to sustain the fusion power in the plasma core and may be crucial in reducing first-wall tritium inventories by a process of "isotopic fueling" in which tritium-rich pellets fuel the burning plasma core and deuterium gas fuels the edge. This repeating single-stage pneumatic pellet injector, called the Tritium-Proof-of-Principle Phase II (TPOP-II) Pellet Injector, has a piston-driven mechanical extruder andmore » is designed to extrude and accelerate hydrogenic pellets sized for the ITER device. The TPOP-II program has the following development goals: evaluate the feasibility of extruding tritium and deuterium-tritium (D-T) mixtures for use in future pellet injection systems; determine the mechanical and thermal properties of tritium and D-T extrusions; integrate, test, and evaluate the extruder in a repeating, single-stage light gas gun that is sized for the ITER application (pellet diameter -7 to 8 mm); evaluate options for recycling propellant and extruder exhaust gas; and evaluate operability and reliability of ITER prototypical fueling systems in an environment of significant tritium inventory that requires secondary and room containment systems. In tests with deuterium feed at ORNL, up to 13 pellets per extrusion have been extruded at rates up to 1 Hz and accelerated to speeds of 1.0 to 1.1 km/s, using hydrogen propellant gas at a supply pressure of 65 bar. Initially, deuterium pellets 7.5 mm in diameter and 11 mm in length were produced-the largest cryogenic pellets produced by the fusion program to date. These pellets represent about a 10% density perturbation to ITER. Subsequently, the extruder nozzle was modified to produce pellets that are almost 7.5-mm right circular cylinders. Tritium and D-T pellets have been produced in experiments at the Los Alamos National Laboratory Tritium Systems Test Assembly. About 38 g of tritium have been utilized in the experiment. The tritium was received in eight batches, six from product containers and two from the Isotope Separation System. Two types of runs were made: those in which the material was only extruded and those in which pellets were produced and fired with deuterium propellant. A total of 36 TZ runs and 28 D-T runs have been made. A total of 36 pure tritium runs and 28 D-T mixture runs were made. Extrusion experiments indicate that both T2 and D-T will require higher extrusion forces than D2 by about a factor of two.« less
The Protein Interaction Network of Bacteriophage Lambda with Its Host, Escherichia coli
Blasche, Sonja; Wuchty, Stefan; Rajagopala, Seesandra V.
2013-01-01
Although most of the 73 open reading frames (ORFs) in bacteriophage λ have been investigated intensively, the function of many genes in host-phage interactions remains poorly understood. Using yeast two-hybrid screens of all lambda ORFs for interactions with its host Escherichia coli, we determined a raw data set of 631 host-phage interactions resulting in a set of 62 high-confidence interactions after multiple rounds of retesting. These links suggest novel regulatory interactions between the E. coli transcriptional network and lambda proteins. Targeted host proteins and genes required for lambda infection are enriched among highly connected proteins, suggesting that bacteriophages resemble interaction patterns of human viruses. Lambda tail proteins interact with both bacterial fimbrial proteins and E. coli proteins homologous to other phage proteins. Lambda appears to dramatically differ from other phages, such as T7, because of its unusually large number of modified and processed proteins, which reduces the number of host-virus interactions detectable by yeast two-hybrid screens. PMID:24049175
Simultaneous display of two large proteins on the head and tail of bacteriophage lambda
2013-01-01
Background Consistent progress in the development of bacteriophage lambda display platform as an alternative to filamentous phage display system was achieved in the recent years. The lambda phage has been engineered to display efficiently multiple copies of peptides or even large protein domains providing a powerful tool for screening libraries of peptides, proteins and cDNA. Results In the present work we describe an original method for dual display of large proteins on the surface of lambda particles. An anti-CEA single-chain antibody fragment and green fluorescent protein or alkaline phosphatase were simultaneously displayed by engineering both gpD and gpV lambda proteins. Conclusions Here we show that such modified phage particles can be used for the detection of target molecules in vitro and in vivo. Dual expression of functional moieties on the surface of the lambda phage might open the way to generation of a new class of diagnostic and therapeutic targeted nanoparticles. PMID:24073829
Selection of Optical Glasses Using Buchdahl's Chromatic Coordinate
NASA Technical Reports Server (NTRS)
Griffin, DeVon W.
1999-01-01
This investigation attempted to extend the method of reducing the size of glass catalogs to a global glass selection technique with the hope of guiding glass catalog offerings. Buchdahl's development of optical aberration coefficients included a transformation of the variable in the dispersion equation from wavelength to a chromatic coordinate omega defined as omega = (lambda - lambda(sub 0))/ 1 + 2.5(lambda - lambda(sub 0)) where lambda is the wavelength at which the wavelength is calculated and lambda(sub 0) is a base wavelength about which the expansion is performed. The advantage of this approach is that the dispersion equation may be written in terms of a simple power series and permits direct calculation of dispersion coefficients. While several promising examples were given, a systematic application of the technique to an entire glass catalog and analysis of the subsequent predictions was not performed. The goal of this work was to apply the technique in a systematic fashion to glasses in the Schoft catalog and assess the quality of the predictions.
Chester, G; Sabapathy, N N; Woollen, B H
1992-01-01
Icon 10 WP insecticide, a wettable powder formulation containing 10% lambda-cyhalothrin, was evaluated for possible adverse effects on the health of spraymen and villagers during treatment of dwellings for malaria vector control. Skin sensory effects and occasional coughing and sneezing in confined spaces were the only symptoms noted by the workers resulting from the handling and spraying of the insecticide. Absorption of lambda-cyhalothrin was estimated by determining its metabolites in urine and serum. The average amount of lambda-cyhalothrin absorbed by the workers per day (54 micrograms) represents less than 0.0001% (< 1 micrograms.kg-1.day-1) of the average daily amount of the substance handled. Only a small proportion of villagers showed detectable levels of lambda-cyhalothrin metabolites in their urine. Absorption of lambda-cyhalothrin from the formulation tested was therefore very low and, apart from the nuisance of skin sensory effects, there should be no risk to the health of workers or to the villagers whose dwellings are treated.
Chester, G.; Sabapathy, N. N.; Woollen, B. H.
1992-01-01
Icon 10 WP insecticide, a wettable powder formulation containing 10% lambda-cyhalothrin, was evaluated for possible adverse effects on the health of spraymen and villagers during treatment of dwellings for malaria vector control. Skin sensory effects and occasional coughing and sneezing in confined spaces were the only symptoms noted by the workers resulting from the handling and spraying of the insecticide. Absorption of lambda-cyhalothrin was estimated by determining its metabolites in urine and serum. The average amount of lambda-cyhalothrin absorbed by the workers per day (54 micrograms) represents less than 0.0001% (< 1 micrograms.kg-1.day-1) of the average daily amount of the substance handled. Only a small proportion of villagers showed detectable levels of lambda-cyhalothrin metabolites in their urine. Absorption of lambda-cyhalothrin from the formulation tested was therefore very low and, apart from the nuisance of skin sensory effects, there should be no risk to the health of workers or to the villagers whose dwellings are treated. PMID:1464147
Two-dimensional energy spectra in high-Reynolds-number turbulent boundary layers
NASA Astrophysics Data System (ADS)
Chandran, Dileep; Baidya, Rio; Monty, Jason P.; Marusic, Ivan
2017-09-01
Here we report the measurements of two-dimensional (2-D) spectra of the streamwise velocity ($u$) in a high Reynolds number turbulent boundary layer. A novel experiment employing multiple hot-wire probes was carried out at friction Reynolds numbers ranging from 2400 to 26000. Taylor's frozen turbulence hypothesis is used to convert temporal-spanwise information into a 2-D spatial spectrum which shows the contribution of streamwise ($\\lambda_x$) and spanwise ($\\lambda_y$) length scales to the streamwise variance at a given wall height ($z$). At low Reynolds numbers, the shape of the 2-D spectra at a constant energy level shows $\\lambda_y/z \\sim (\\lambda_x/z)^{1/2}$ behaviour at larger scales, which is in agreement with the existing literature at a matched Reynolds number obtained from direct numerical simulations. However, at high Reynolds numbers, it is observed that the square-root relationship tends towards a linear relationship ($\\lambda_y \\sim \\lambda_x$) as required for self-similarity and predicted by the attached eddy hypothesis.
Physical parameters of lambda Bootis stars
NASA Astrophysics Data System (ADS)
Solano, E.; Paunzen, E.; Pintado, O. I.; Córdoba; Varela, J.
2001-08-01
This is the first of two papers whose main goal is to update and improve the information available on the physical properties of the lambda Bootis stars. The determination of the stellar parameters is of fundamental importance to shed light into the different theories proposed to explain the lambda Bootis phenomenon. With this aim, projected rotational velocities, effective temperatures, surface gravities and chemical abundances of a sample of suspected lambda Bootis stars have been calculated. Five objects showing composite spectra typical of binary systems were found in our analysis. The abundance distribution of the program stars does not resemble the chemical composition of the class prototype, lambda Boo, which poses some concerns regarding the idea of a well-defined, chemically homogeneous group of stars. A possible relation between rotational velocities and the lambda Bootis phenomenon has been found. This result would be in agreement with the accretion scenario proposed by Turcotte & Charbonneau (\\cite{Turcotte93}). Figure 3 is only available in electronic form at http://www.edpsciences.org
D'Ávila, Vinicius A; Barbosa, Wagner F; Guedes, Raul N C; Cutler, G Christopher
2018-05-28
Insecticides can affect biological control by parasitoids. Here, we examined the lethal and sublethal effects of two conventional insecticides, imidacloprid and lambda-cyhalothrin, and a reduced-risk bioinsecticide, spinosad, on the aphid parasitoid Aphidius colemani Viereck (Hymenoptera: Braconidae). Concentration-mortality curves generated from insecticide residue bioassays found that wasps were nearly 20-fold more susceptible to spinosad than imidacloprid and lambda-cyhalothrin. Imidacloprid and lambda-cyhalothrin compromised adult parasitoid longevity, but not as dramatically as spinosad: concentrations >200 ng spinosad/cm2 reduced wasp longevity by half. Imidacloprid and lambda-cyhalothrin also compromised aphid parasitism by wasps. Although increasing imidacloprid concentrations led to increased host viability and reduced progeny production, lambda-cyhalothrin did not affect viability of parasitized hosts or parasitoid progeny production in a dose-dependent manner. Our results demonstrate that reduced risk bioinsecticide products like spinosad can be more toxic to biological control agents than certain conventional insecticides.
NASA Technical Reports Server (NTRS)
Ayres, Thomas R.; Wiedemann, Gunter R.
1989-01-01
A more extensive and detailed non-LTE simulation of the Delta v = 1 bands of CO than attempted previously is reported. The equations of statistical equilibrium are formulated for a model molecule containing 10 bound vibrational levels, each split into 121 rotational substates and connected by more than 1000 radiative transitions. Solutions are obtained for self-consistent populations and radiation fields by iterative application of the 'Lambda-operator' to an initial LTE distribution. The formalism is used to illustrate models of the sun and Arcturus. For the sun, negligible departures from LTE are found in either a theoretical radiative-equilibrium photosphere with outwardly falling temperatures in its highest layers or in a semiempirical hot chromosphere that reproduces the spatially averaged emission cores of Ca II H and K. The simulations demonstrate that the puzzling 'cool cores' of the CO Delta V = 1 bands observed in limb spectra of the sun and in flux spectra of Arcturus cannot be explained simply by non-LTE scattering effects.
Fredlund, Paul; Hillson, Jan; Gray, Todd; Shemanski, Lynn; Dimitrova, Dessislava; Srinivasan, Subasree
2015-11-01
Peginterferon alfa (alfa) increases the risk of autoimmune disease. Peginterferon lambda-1a (Lambda) acts through a receptor with a more liver-specific distribution compared to the alfa receptor. In a phase-2b study, 525 treatment-naive patients with chronic hepatitis C virus (HCV) infection received ribavirin and Lambda interferon (120, 180, or 240 μg) or alfa interferon (180 μg) for 24 (genotypes 2 and 3) or 48 (genotypes 1 and 4) weeks. Retrospective analysis found that adverse events of MedDRA-coded thyroid dysfunction and abnormal levels of thyroid-stimulating hormone (TSH) were significantly more frequent with alfa versus Lambda (12% versus 2.6% and 15.2% versus 3.4%, respectively, both P<0.0001). Most Lambda recipients with abnormal TSH had levels below the lower limit of normal; the frequency of low and high TSH was similar in alfa recipients with abnormal TSH. Blinded review by an endocrinologist found that new-onset primary hypothyroidism or painless thyroiditis was less frequent with Lambda versus alfa (0.5% and 1.8% versus 5.3% and 7.5%, respectively, P<0.0001). Most TSH elevations reflected new-onset hypothyroidism requiring treatment, while most markedly suppressed TSH values reflected probable painless thyroiditis and resolved without sequelae. In conclusion, HCV-infected patients treated with Lambda/ribavirin experienced fewer adverse events of thyroid dysfunction compared with patients treated with alfa/ribavirin.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Brick, D.H.; Widgoff, M.; Beilliere, P.
1992-02-01
We have used the Fermilab 30-in. bubble-chamber--hybrid spectrometer to study neutral-strange-particle production in the interactions of 200-GeV/{ital c} protons and {pi}{sup +} and {ital K}{sup +} mesons with nuclei of gold, silver, and magnesium. Average multiplicities and inclusive cross sections for {ital K}{sup 0} and {Lambda} are measured, and a power law is found to give a good description of their {ital A} dependence. The exponent characterizing the {ital A} dependence is consistent with being the same for {ital K}{sup 0} and {Lambda} production, and also the same for proton and {pi}{sup +} beams. Average {ital K}{sup 0} and {Lambda}more » multiplicities, as well as their ratio, have been measured as functions of the numbers of projectile collisions {nu}{sub {ital p}} and secondary collisions {nu}{sub {ital s}} in the nucleus, and indicate that rescattering contributes significantly to enhancement of {Lambda} production but not to {ital K}{sup 0} production. The properties of events with multiple {ital K}{sup 0}'s or {Lambda}'s also corroborate this conclusion. {ital K}{sup 0} rapidities are in the central region and decrease gently with increasing {nu}{sub {ital p}}, while {Lambda} rapidities are in the target-fragmentation region and are independent of {nu}{sub {ital p}}. {ital K}{sup 0} and {Lambda} multiplicities increase with the rapidity loss of the projectile, but their rapidities do not.« less
THERMALLY DRIVEN ATMOSPHERIC ESCAPE: TRANSITION FROM HYDRODYNAMIC TO JEANS ESCAPE
DOE Office of Scientific and Technical Information (OSTI.GOV)
Volkov, Alexey N.; Johnson, Robert E.; Tucker, Orenthal J.
2011-03-10
Thermally driven escape from planetary atmospheres changes in nature from an organized outflow (hydrodynamic escape) to escape on a molecule-by-molecule basis (Jeans escape) with increasing Jeans parameter, {lambda}, the ratio of the gravitational to thermal energy of the atmospheric molecules. This change is described here for the first time using the direct simulation Monte Carlo method. When heating is predominantly below the lower boundary of the simulation region, R{sub 0}, and well below the exobase of a single-component atmosphere, the nature of the escape process changes over a surprisingly narrow range of Jeans parameters, {lambda}{sub 0}, evaluated at R{sub 0}.more » For an atomic gas, the transition occurs over {lambda}{sub 0} {approx} 2-3, where the lower bound, {lambda}{sub 0} {approx} 2.1, corresponds to the upper limit for isentropic, supersonic outflow. For {lambda}{sub 0} > 3 escape occurs on a molecule-by-molecule basis and we show that, contrary to earlier suggestions, for {lambda}{sub 0} > {approx}6 the escape rate does not deviate significantly from the familiar Jeans rate. In a gas composed of diatomic molecules, the transition shifts to {lambda}{sub 0} {approx} 2.4-3.6 and at {lambda}{sub 0} > {approx}4 the escape rate increases a few tens of percent over that for the monatomic gas. Scaling by the Jeans parameter and the Knudsen number, these results can be applied to thermally induced escape of the major species from solar and extrasolar planets.« less
Active Knowledge Structures for Natural Language Processing.
1991-01-01
specialist belief: Assume there is a lambda-expression "(LAMBDA L) immed-type-ofL" and Z = ((LAMBDA L) immed-type-of L) ( thalassemia ), we can describe...SPEC) -> ([AVG-PERSON] -> (VAL-FOR) -> CGREEK-PLCE)3 This expresses the various levels of specialized knowledge of thalassemia , depending on
GPU-accelerated regularized iterative reconstruction for few-view cone beam CT
DOE Office of Scientific and Technical Information (OSTI.GOV)
Matenine, Dmitri, E-mail: dmitri.matenine.1@ulaval.ca; Goussard, Yves, E-mail: yves.goussard@polymtl.ca; Després, Philippe, E-mail: philippe.despres@phy.ulaval.ca
2015-04-15
Purpose: The present work proposes an iterative reconstruction technique designed for x-ray transmission computed tomography (CT). The main objective is to provide a model-based solution to the cone-beam CT reconstruction problem, yielding accurate low-dose images via few-views acquisitions in clinically acceptable time frames. Methods: The proposed technique combines a modified ordered subsets convex (OSC) algorithm and the total variation minimization (TV) regularization technique and is called OSC-TV. The number of subsets of each OSC iteration follows a reduction pattern in order to ensure the best performance of the regularization method. Considering the high computational cost of the algorithm, it ismore » implemented on a graphics processing unit, using parallelization to accelerate computations. Results: The reconstructions were performed on computer-simulated as well as human pelvic cone-beam CT projection data and image quality was assessed. In terms of convergence and image quality, OSC-TV performs well in reconstruction of low-dose cone-beam CT data obtained via a few-view acquisition protocol. It compares favorably to the few-view TV-regularized projections onto convex sets (POCS-TV) algorithm. It also appears to be a viable alternative to full-dataset filtered backprojection. Execution times are of 1–2 min and are compatible with the typical clinical workflow for nonreal-time applications. Conclusions: Considering the image quality and execution times, this method may be useful for reconstruction of low-dose clinical acquisitions. It may be of particular benefit to patients who undergo multiple acquisitions by reducing the overall imaging radiation dose and associated risks.« less
Shading correction assisted iterative cone-beam CT reconstruction
NASA Astrophysics Data System (ADS)
Yang, Chunlin; Wu, Pengwei; Gong, Shutao; Wang, Jing; Lyu, Qihui; Tang, Xiangyang; Niu, Tianye
2017-11-01
Recent advances in total variation (TV) technology enable accurate CT image reconstruction from highly under-sampled and noisy projection data. The standard iterative reconstruction algorithms, which work well in conventional CT imaging, fail to perform as expected in cone beam CT (CBCT) applications, wherein the non-ideal physics issues, including scatter and beam hardening, are more severe. These physics issues result in large areas of shading artifacts and cause deterioration to the piecewise constant property assumed in reconstructed images. To overcome this obstacle, we incorporate a shading correction scheme into low-dose CBCT reconstruction and propose a clinically acceptable and stable three-dimensional iterative reconstruction method that is referred to as the shading correction assisted iterative reconstruction. In the proposed method, we modify the TV regularization term by adding a shading compensation image to the reconstructed image to compensate for the shading artifacts while leaving the data fidelity term intact. This compensation image is generated empirically, using image segmentation and low-pass filtering, and updated in the iterative process whenever necessary. When the compensation image is determined, the objective function is minimized using the fast iterative shrinkage-thresholding algorithm accelerated on a graphic processing unit. The proposed method is evaluated using CBCT projection data of the Catphan© 600 phantom and two pelvis patients. Compared with the iterative reconstruction without shading correction, the proposed method reduces the overall CT number error from around 200 HU to be around 25 HU and increases the spatial uniformity by a factor of 20 percent, given the same number of sparsely sampled projections. A clinically acceptable and stable iterative reconstruction algorithm for CBCT is proposed in this paper. Differing from the existing algorithms, this algorithm incorporates a shading correction scheme into the low-dose CBCT reconstruction and achieves more stable optimization path and more clinically acceptable reconstructed image. The method proposed by us does not rely on prior information and thus is practically attractive to the applications of low-dose CBCT imaging in the clinic.
Hielscher, Andreas H; Bartel, Sebastian
2004-02-01
Optical tomography (OT) is a fast developing novel imaging modality that uses near-infrared (NIR) light to obtain cross-sectional views of optical properties inside the human body. A major challenge remains the time-consuming, computational-intensive image reconstruction problem that converts NIR transmission measurements into cross-sectional images. To increase the speed of iterative image reconstruction schemes that are commonly applied for OT, we have developed and implemented several parallel algorithms on a cluster of workstations. Static process distribution as well as dynamic load balancing schemes suitable for heterogeneous clusters and varying machine performances are introduced and tested. The resulting algorithms are shown to accelerate the reconstruction process to various degrees, substantially reducing the computation times for clinically relevant problems.
A Block Iterative Finite Element Model for Nonlinear Leaky Aquifer Systems
NASA Astrophysics Data System (ADS)
Gambolati, Giuseppe; Teatini, Pietro
1996-01-01
A new quasi three-dimensional finite element model of groundwater flow is developed for highly compressible multiaquifer systems where aquitard permeability and elastic storage are dependent on hydraulic drawdown. The model is solved by a block iterative strategy, which is naturally suggested by the geological structure of the porous medium and can be shown to be mathematically equivalent to a block Gauss-Seidel procedure. As such it can be generalized into a block overrelaxation procedure and greatly accelerated by the use of the optimum overrelaxation factor. Results for both linear and nonlinear multiaquifer systems emphasize the excellent computational performance of the model and indicate that convergence in leaky systems can be improved up to as much as one order of magnitude.
NASA Technical Reports Server (NTRS)
Reichelt, Mark
1993-01-01
In this paper we describe a novel generalized SOR (successive overrelaxation) algorithm for accelerating the convergence of the dynamic iteration method known as waveform relaxation. A new convolution SOR algorithm is presented, along with a theorem for determining the optimal convolution SOR parameter. Both analytic and experimental results are given to demonstrate that the convergence of the convolution SOR algorithm is substantially faster than that of the more obvious frequency-independent waveform SOR algorithm. Finally, to demonstrate the general applicability of this new method, it is used to solve the differential-algebraic system generated by spatial discretization of the time-dependent semiconductor device equations.
UFO: A THREE-DIMENSIONAL NEUTRON DIFFUSION CODE FOR THE IBM 704
DOE Office of Scientific and Technical Information (OSTI.GOV)
Auerbach, E.H.; Jewett, J.P.; Ketchum, M.A.
A description of UFO, a code for the solution of the fewgroup neutron diffusion equation in three-dimensional Cartesian coordinates on the IBM 704, is given. An accelerated Liebmann flux iteration scheme is used, and optimum parameters can be calculated by the code whenever they are required. The theory and operation of the program are discussed. (auth)
A Machine Learning System for Analyzing Human Tactics in a Game
NASA Astrophysics Data System (ADS)
Ito, Hirotaka; Tanaka, Toshimitsu; Sugie, Noboru
In order to realize advanced man-machine interfaces, it is desired to develop a system that can infer the mental state of human users and then return appropriate responses. As the first step toward the above goal, we developed a system capable of inferring human tactics in a simple game played between the system and a human. We present a machine learning system that plays a color expectation game. The system infers the tactics of the opponent, and then decides the action based on the result. We employed a modified version of classifier system like XCS in order to design the system. In addition, three methods are proposed in order to accelerate the learning rate. They are a masking method, an iterative method, and tactics templates. The results of computer experiments confirmed that the proposed methods effectively accelerate the machine learning. The masking method and the iterative method are effective to a simple strategy that considers only a part of past information. However, study speed of these methods is not enough for the tactics that refers to a lot of past information. For the case, the tactics template was able to settle the study rapidly when the tactics is identified.
Development of the Long Pulse Negative Ion Source for ITER
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hemsworth, R.S.; Svensson, L.; Esch, H.P.L. de
2005-04-06
A model of the ion source designed for the neutral beam injectors of the International Thermonuclear Experimental Reactor (ITER), the KAMABOKO III ion source, is being tested on the MANTIS test stand at the DRFC Cadarache in collaboration with JAERI, Japan, who designed and supplied the ion source. The ion source is attached to a 3 grid 30 keV accelerator (also supplied by JAERI) and the accelerated negative ion current is determined from the energy deposited on a calorimeter located 1.6 m from the source.During experiments on MANTIS three adverse effects of long pulse operation were found: The negative ionmore » current to the calorimeter is {approx_equal}50% of that obtained from short pulse operation Increasing the plasma grid (PG) temperature results in {<=}40% enhancement in negative ion yield, substantially below that reported for short pulse operation, {>=}100%. The caesium 'consumption' is up to 1500 times that expected.Results presented here indicate that each of these is, at least partially, explained by thermal effects. Additionally presented are the results of a detailed characterisation of the source, which enable the most efficient mode of operation to be identified.« less
On some Aitken-like acceleration of the Schwarz method
NASA Astrophysics Data System (ADS)
Garbey, M.; Tromeur-Dervout, D.
2002-12-01
In this paper we present a family of domain decomposition based on Aitken-like acceleration of the Schwarz method seen as an iterative procedure with a linear rate of convergence. We first present the so-called Aitken-Schwarz procedure for linear differential operators. The solver can be a direct solver when applied to the Helmholtz problem with five-point finite difference scheme on regular grids. We then introduce the Steffensen-Schwarz variant which is an iterative domain decomposition solver that can be applied to linear and nonlinear problems. We show that these solvers have reasonable numerical efficiency compared to classical fast solvers for the Poisson problem or multigrids for more general linear and nonlinear elliptic problems. However, the salient feature of our method is that our algorithm has high tolerance to slow network in the context of distributed parallel computing and is attractive, generally speaking, to use with computer architecture for which performance is limited by the memory bandwidth rather than the flop performance of the CPU. This is nowadays the case for most parallel. computer using the RISC processor architecture. We will illustrate this highly desirable property of our algorithm with large-scale computing experiments.
Fast, Accurate and Shift-Varying Line Projections for Iterative Reconstruction Using the GPU
Pratx, Guillem; Chinn, Garry; Olcott, Peter D.; Levin, Craig S.
2013-01-01
List-mode processing provides an efficient way to deal with sparse projections in iterative image reconstruction for emission tomography. An issue often reported is the tremendous amount of computation required by such algorithm. Each recorded event requires several back- and forward line projections. We investigated the use of the programmable graphics processing unit (GPU) to accelerate the line-projection operations and implement fully-3D list-mode ordered-subsets expectation-maximization for positron emission tomography (PET). We designed a reconstruction approach that incorporates resolution kernels, which model the spatially-varying physical processes associated with photon emission, transport and detection. Our development is particularly suitable for applications where the projection data is sparse, such as high-resolution, dynamic, and time-of-flight PET reconstruction. The GPU approach runs more than 50 times faster than an equivalent CPU implementation while image quality and accuracy are virtually identical. This paper describes in details how the GPU can be used to accelerate the line projection operations, even when the lines-of-response have arbitrary endpoint locations and shift-varying resolution kernels are used. A quantitative evaluation is included to validate the correctness of this new approach. PMID:19244015
T(sub lambda) Depression by a Heat Current Along the lambda-Line
NASA Technical Reports Server (NTRS)
Liu, Yuanming; Larson, Melora; Iraelsson, Ulf E.
1999-01-01
We report measurements of the depression of the superfluid transition temperature by a heat current (1 less than or = Q less than or = 100 microW/sq cm) along the lambda-line (SVP less than or = P less than or = 21.6 bar). At P = 21.6 bar, measurements were also performed in a reduced gravity (0.2g). Experimental results show that the pressure dependence of the depression and the gravity effect on the measurements are small, in qualitative agreement with theoretical predictions. Keywords: superfluid helium; Lambda transition; heat current
Biomechanical stability analysis of the lambda-model controlling one joint.
Lan, L; Zhu, K Y
2007-06-01
Computer modeling and control of the human motor system might be helpful for understanding the mechanism of human motor system and for the diagnosis and treatment of neuromuscular disorders. In this paper, a brief view of the equilibrium point hypothesis for human motor system modeling is given, and the lambda-model derived from this hypothesis is studied. The stability of the lambda-model based on equilibrium and Jacobian matrix is investigated. The results obtained in this paper suggest that the lambda-model is stable and has a unique equilibrium point under certain conditions.
Phase correlation of laser waves with arbitrary frequency spacing.
Huss, A F; Lammegger, R; Neureiter, C; Korsunsky, E A; Windholz, L
2004-11-26
The theoretically predicted correlation of laser phase fluctuations in Lambda-type interaction schemes is experimentally demonstrated. We show that the mechanism of correlation in a Lambda scheme is restricted to high-frequency noise components, whereas in a double-Lambda scheme, due to the laser phase locking in a closed-loop interaction, it extends to all noise frequencies. In this case the correlation is weakly sensitive to coherence losses. Thus the double-Lambda scheme can be used to correlate electromagnetic fields with carrier frequency differences beyond the GHz regime.
[Extraction of lambda-cyhalothrin from aqueous dioxan solutions].
Shormanov, V K; Chigareva, E N; Belousova, O V
2011-01-01
The results of extraction of lambda-cigalotrin from dioxan aqueous solutions by hydrophobic organic solvents are presented. It is shown that the degree of extraction depends on the nature of the extractant, the water to dioxan ratio, and saturation of the water-dioxan layer with the electrolyte. The highest efficiency of lambda-cigalotrin extraction was achieved using chlorophorm as a solvent under desalination conditions. The extraction factor was calculated necessary to obtain the desired amount of lambda-cigalotrin from the water-dioxan solution (4:1) with the help of the extractants being used.
Far-infrared spectrophotometer for astronomical observations
NASA Technical Reports Server (NTRS)
Moseley, H.; Silverberg, R. F.
1981-01-01
A liquid-helium-cooled far infrared spectrophotometer was built and used to make low resolution observations of the continua of several kinds of astronomical objects using the Kuiper Airborne Observatory. This instrument fills a gap in both sensitivity to continuum sources and spectral resolution between the broadband photometers with lambda/Delta lambda approximately 1 and spectrometers with lambda/Delta lambda greater than 50. While designed primarily to study planetary nebulae, the instrument permits study of the shape of the continua of many weak sources which cannot easily be observed with high resolution systems.
[Spectral emissivity of thin films].
Zhong, D
2001-02-01
In this paper, the contribution of multiple reflections in thin film to the spectral emissivity of thin films of low absorption is discussed. The expression of emissivity of thin films derived here is related to the thin film thickness d and the optical constants n(lambda) and k(lambda). It is shown that in the special case d-->infinity the emissivity of thin films is equivalent to that of the bulk material. Realistic numerical and more precise general numerical results for the dependence of the emissivity on d, n(lambda) and k(lambda) are given.
Liao, Chun-Hua; He, Xu-Jiang; Wang, Zi-Long; Barron, Andrew B; Zhang, Bo; Zeng, Zhi-Jiang; Wu, Xiao-Bo
2018-07-01
Pesticides are considered one of the major contemporary stressors of honey bee health. In this study, the effects of short-term exposure to lambda-cyhalothrin on lifespan, learning, and memory-related characteristics of Apis mellifera were systematically examined. Short-term exposure to lambda-cyhalothrin in worker bees reduced lifespan, affected learning and memory performance, reduced the homing ability, and influenced the expression levels of two learning and memory-related genes of A. mellifera. This research identifies the nature of the sublethal effects of lambda-cyhalothrin on bees and the level of exposure that can be harmful to bee health. This new information will assist in establishing guidelines for the safe use of lambda-cyhalothrin in the field.
Quantitation of IgG kappa and IgG lambda in the cerebrospinal fluid by sandwich ELISA method.
Zeman, David; Kušnierová, Pavlína; Bojková, Jana; Všianský, František; Zapletalová, Olga
2017-01-01
IgG kappa and IgG lambda concentrations were quantified in 96 paired CSF and sera using Hevylite™ antibodies in an in-house developed sandwich ELISA method. In 56 of these samples, the results were compared with a qualitative isoelectric focusing/affinity-mediated immunoblotting assay for oligoclonal IgG kappa and IgG lambda. Normal IgG kappa/lambda ratio in the CSF was the same as in serum. In 19/33 patients with intrathecal oligoclonal IgG synthesis, skewed IgG kappa/lambda ratio was observed (increased in 16 and decreased in 3 cases). The analysis of light chain composition of intrathecally synthesised immunoglobulins could contribute to our understanding of intrathecal humoral immune response, although its diagnostic utility is limited.
Adams, J; Adler, C; Aggarwal, M M; Ahammed, Z; Amonett, J; Anderson, B D; Anderson, M; Arkhipkin, D; Averichev, G S; Badyal, S K; Balewski, J; Barannikova, O; Barnby, L S; Baudot, J; Bekele, S; Belaga, V V; Bellwied, R; Berger, J; Bezverkhny, B I; Bhardwaj, S; Bhaskar, P; Bhati, A K; Bichsel, H; Billmeier, A; Bland, L C; Blyth, C O; Bonner, B E; Botje, M; Boucham, A; Brandin, A; Bravar, A; Cadman, R V; Cai, X Z; Caines, H; Calderón de la Barca Sánchez, M; Carroll, J; Castillo, J; Castro, M; Cebra, D; Chaloupka, P; Chattopadhyay, S; Chen, H F; Chen, Y; Chernenko, S P; Cherney, M; Chikanian, A; Choi, B; Christie, W; Coffin, J P; Cormier, T M; Cramer, J G; Crawford, H J; Das, D; Das, S; Derevschikov, A A; Didenko, L; Dietel, T; Dong, W J; Dong, X; Draper, J E; Du, F; Dubey, A K; Dunin, V B; Dunlop, J C; Dutta Majumdar, M R; Eckardt, V; Efimov, L G; Emelianov, V; Engelage, J; Eppley, G; Erazmus, B; Estienne, M; Fachini, P; Faine, V; Faivre, J; Fatemi, R; Filimonov, K; Filip, P; Finch, E; Fisyak, Y; Flierl, D; Foley, K J; Fu, J; Gagliardi, C A; Gagunashvili, N; Gans, J; Ganti, M S; Gaudichet, L; Germain, M; Geurts, F; Ghazikhanian, V; Ghosh, P; Gonzalez, J E; Grachov, O; Grigoriev, V; Gronstal, S; Grosnick, D; Guedon, M; Guertin, S M; Gupta, A; Gushin, E; Gutierrez, T D; Hallman, T J; Hardtke, D; Harris, J W; Heinz, M; Henry, T W; Heppelmann, S; Herston, T; Hippolyte, B; Hirsch, A; Hjort, E; Hoffmann, G W; Horsley, M; Huang, H Z; Huang, S L; Humanic, T J; Igo, G; Ishihara, A; Jacobs, P; Jacobs, W W; Janik, M; Jiang, H; Johnson, I; Jones, P G; Judd, E G; Kabana, S; Kaneta, M; Kaplan, M; Keane, D; Khodyrev, V Yu; Kiryluk, J; Kisiel, A; Klay, J; Klein, S R; Klyachko, A; Koetke, D D; Kollegger, T; Kopytine, M; Kotchenda, L; Kovalenko, A D; Kramer, M; Kravtsov, P; Kravtsov, V I; Krueger, K; Kuhn, C; Kulikov, A I; Kumar, A; Kunde, G J; Kunz, C L; Kutuev, R Kh; Kuznetsov, A A; Lamont, M A C; Landgraf, J M; Lange, S; Lansdell, C P; Lasiuk, B; Laue, F; Lauret, J; Lebedev, A; Lednický, R; LeVine, M J; Li, C; Li, Q; Lindenbaum, S J; Lisa, M A; Liu, F; Liu, L; Liu, Z; Liu, Q J; Ljubicic, T; Llope, W J; Long, H; Longacre, R S; Lopez-Noriega, M; Love, W A; Ludlam, T; Lynn, D; Ma, J; Ma, Y G; Magestro, D; Mahajan, S; Mangotra, L K; Mahapatra, D P; Majka, R; Manweiler, R; Margetis, S; Markert, C; Martin, L; Marx, J; Matis, H S; Matulenko, Yu A; McShane, T S; Meissner, F; Melnick, Yu; Meschanin, A; Messer, M; Miller, M L; Milosevich, Z; Minaev, N G; Mironov, C; Mishra, D; Mitchell, J; Mohanty, B; Molnar, L; Moore, C F; Mora-Corral, M J; Morozov, D A; Morozov, V; de Moura, M M; Munhoz, M G; Nandi, B K; Nayak, S K; Nayak, T K; Nelson, J M; Nevski, P; Nikitin, V A; Nogach, L V; Norman, B; Nurushev, S B; Odyniec, G; Ogawa, A; Okorokov, V; Oldenburg, M; Olson, D; Paic, G; Pandey, S U; Pal, S K; Panebratsev, Y; Panitkin, S Y; Pavlinov, A I; Pawlak, T; Perevoztchikov, V; Perkins, C; Peryt, W; Petrov, V A; Phatak, S C; Picha, R; Planinic, M; Pluta, J; Porile, N; Porter, J; Poskanzer, A M; Potekhin, M; Potrebenikova, E; Potukuchi, B V K S; Prindle, D; Pruneau, C; Putschke, J; Rai, G; Rakness, G; Raniwala, R; Raniwala, S; Ravel, O; Ray, R L; Razin, S V; Reichhold, D; Reid, J G; Renault, G; Retiere, F; Ridiger, A; Ritter, H G; Roberts, J B; Rogachevski, O V; Romero, J L; Rose, A; Roy, C; Ruan, L J; Sahoo, R; Sakrejda, I; Salur, S; Sandweiss, J; Savin, I; Schambach, J; Scharenberg, R P; Schmitz, N; Schroeder, L S; Schweda, K; Seger, J; Seliverstov, D; Seyboth, P; Shahaliev, E; Shao, M; Sharma, M; Shestermanov, K E; Shimanskii, S S; Singaraju, R N; Simon, F; Skoro, G; Smirnov, N; Snellings, R; Sood, G; Sorensen, P; Sowinski, J; Spinka, H M; Srivastava, B; Stanislaus, S; Stock, R; Stolpovsky, A; Strikhanov, M; Stringfellow, B; Struck, C; Suaide, A A P; Sugarbaker, E; Suire, C; Sumbera, M; Surrow, B; Symons, T J M; de Toledo, A Szanto; Szarwas, P; Tai, A; Takahashi, J; Tang, A H; Thein, D; Thomas, J H; Tikhomirov, V; Tokarev, M; Tonjes, M B; Trainor, T A; Trentalange, S; Tribble, R E; Trivedi, M D; Trofimov, V; Tsai, O; Ullrich, T; Underwood, D G; Van Buren, G; VanderMolen, A M; Vasiliev, A N; Vasiliev, M; Vigdor, S E; Viyogi, Y P; Voloshin, S A; Waggoner, W; Wang, F; Wang, G; Wang, X L; Wang, Z M; Ward, H; Watson, J W; Wells, R; Westfall, G D; Whitten, C; Wieman, H; Willson, R; Wissink, S W; Witt, R; Wood, J; Wu, J; Xu, N; Xu, Z; Xu, Z Z; Yamamoto, E; Yepes, P; Yurevich, V I; Zanevski, Y V; Zborovský, I; Zhang, H; Zhang, W M; Zhang, Z P; Zołnierczuk, P A; Zoulkarneev, R; Zoulkarneeva, J; Zubarev, A N
2004-02-06
We present STAR measurements of the azimuthal anisotropy parameter v(2) and the binary-collision scaled centrality ratio R(CP) for kaons and lambdas (Lambda+Lambda) at midrapidity in Au+Au collisions at square root of s(NN)=200 GeV. In combination, the v(2) and R(CP) particle-type dependencies contradict expectations from partonic energy loss followed by standard fragmentation in vacuum. We establish p(T) approximately 5 GeV/c as the value where the centrality dependent baryon enhancement ends. The K(0)(S) and Lambda+Lambda v(2) values are consistent with expectations of constituent-quark-number scaling from models of hadron formation by parton coalescence or recombination.
NASA Astrophysics Data System (ADS)
Lauinger, Norbert
1999-08-01
Diffractive 3D phase gratings of spherical scatterers dense in hexagonal packing geometry represent adaptively tunable 4D-spatiotemporal filters with trichromatic resonance in visible spectrum. They are described in the (lambda) - chromatic and the reciprocal (nu) -aspects by reciprocal geometric translations of the lightlike Pythagoras theorem, and by the direction cosine for double cones. The most elementary resonance condition in the lightlike Pythagoras theorem is given by the transformation of the grating constants gx, gy, gz of the hexagonal 3D grating to (lambda) h1h2h3 equals (lambda) 111 with cos (alpha) equals 0.5. Through normalization of the chromaticity in the von Laue-interferences to (lambda) 111, the (nu) (lambda) equals (lambda) h1h2h3/(lambda) 111-factor of phase velocity becomes the crucial resonance factor, the 'regulating device' of the spatiotemporal interaction between 3D grating and light, space and time. In the reciprocal space equal/unequal weights and times in spectral metrics result at positions of interference maxima defined by hyperbolas and circles. A database becomes built up by optical interference for trichromatic image preprocessing, motion detection in vector space, multiple range data analysis, patchwide multiple correlations in the spatial frequency spectrum, etc.
Ion Viscosity Mediated by Tangled Magnetic Fields: An Application to Black Hole Accretion Disks
NASA Technical Reports Server (NTRS)
Subramanian, Prasad; Becker, Peter A.; Kafatos, Menas
1996-01-01
We examine the viscosity associated with the shear stress exerted by ions in the presence of a tangled magnetic field. As an application, we consider the effect of this mechanism on the structure of black hole accretion disks. We do not attempt to include a self-consistent description of the magnetic field. Instead, we assume the existence of a tangled field with coherence length lambda(sub coh), which is the average distance between the magnetic 'kinks' that scatter the particles. For simplicity, we assume that the field is self-similar, and take lambda(sub coh) to be a fixed fraction zeta of the local disk height H. Ion viscosity in the presence of magnetic fields is generally taken to be the cross-field viscosity, wherein the effective mean free path is the ion Larmor radius lambda(sub L), which is much less than the ion-ion Coulomb mean free path A(sub ii) in hot accretion disks. However, we arrive at a formulation for a 'hybrid' viscosity in which the tangled magnetic field acts as an intermediary in the transfer of momentum between different layers in the shear flow. The hybrid viscosity greatly exceeds the standard cross-field viscosity when (lambda/lambda(sub L)) much greater than (lambda(sub L)/lambda(sub ii)), where lambda = ((lambda(sub ii)(sup -1) + lambda(sub (coh)(sup -1))(sup -1) is the effective mean free path for the ions. This inequality is well satisfied in hot accretion disks, which suggests that the ions may play a much larger role in the momentum transfer process in the presence of magnetic fields than was previously thought. The effect of the hybrid viscosity on the structure of a steady-state, two-temperature, quasi-Keplerian accretion disk is analyzed. The hybrid viscosity is influenced by the degree to which the magnetic field is tangled (represented by zeta = lambda(sub coh)), and also by the relative accretion rate M/M(sub E), where M(sub E) = L(sub E)/c(sup 2) and L(sub E) is the Eddington luminosity. We find that ion viscosity in the presence of magnetic fields (hybrid viscosity) can dominate over conventional magnetic viscosity for fields that are tangled on sufficiently small scales.
Cosmic vacuum energy decay and creation of cosmic matter.
Fahr, Hans-Jörg; Heyl, Michael
2007-09-01
In the more recent literature on cosmological evolutions of the universe, the cosmic vacuum energy has become a nonrenouncable ingredient. The cosmological constant Lambda, first invented by Einstein, but later also rejected by him, presently experiences an astonishing revival. Interestingly enough, it acts like a constant vacuum energy density would also do. Namely, it has an accelerating action on cosmic dynamics, without which, as it appears, presently obtained cosmological data cannot be conciliated with theory. As we are going to show in this review, however, the concept of a constant vacuum energy density is unsatisfactory for very basic reasons because it would claim for a physical reality that acts upon spacetime and matter dynamics without itself being acted upon by spacetime or matter.
Concise expression of a classical radiation spectrum
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wang, C.
1993-06-01
In this paper we present a concise expression of the classical electromagnetic radiation spectrum of a moving charge. It is shown to be equivalent to the often used and much more complicated form derived from the Lienard-Wiechert potentials when the observation distance [ital R] satisfies the condition [ital R][much gt][gamma][lambda]. The expression reveals a relationship between the radiation spectrum and the motion of the radiation source. It also forms the basis of an efficient computing approach, which is of practical value in numerical calculations of the spectral output of accelerated charges. The advantages of this approach for analytical and numericalmore » applications are discussed and the bending-magnet synchrotron radiation spectrum is calculated according to the approach.« less
NASA Astrophysics Data System (ADS)
Orlova, Ksenia; Spasojevic, Maria; Shprits, Yuri
Particle populations in the inner magnetosphere can change by orders of magnitude on very short time scales. For the last decade observations and theoretical computations showed that resonant interaction of electrons with various plasma waves plays an important role in acceleration and loss mechanisms. Using data from the CRRES plasma wave experiment, we develop quadratic fits to the mean of the wave amplitude squared for plasmaspheric hiss as a function of geomagnetic activity (Kp) and magnetic latitude (lambda) for the dayside (6
Measuring the Accelerations of Water Megamasers in Active Galaxy J0437+2456
NASA Astrophysics Data System (ADS)
Turner, Jeremy; Jeremy Turner
2018-01-01
The Megamaser Cosmology Project is measuring the Hubble constant using observations of 22 GHz water megamasers in the accretion disks of active galaxies within the Hubble flow. This approach uses the dynamics of the megamaser disks to determine their physical sizes and thereby find the angular-diameter distances to galaxies without relying on the cosmic distance ladder. We present Green Bank Telescope observations and analysis of the maser disk in the galaxy J0437+2456, which encircles a 2.9×106 M⊙ supermassive black hole. With spectral monitoring observations spanning over four years, we measure the centripetal acceleration of each individual maser component by tracking its velocity drift over time. These accelerations will be used in later work to model the maser disk and determine the distance to the galaxy. Our acceleration measurements use an iterative least squares fitting technique. For the systemic maser features, we find a mean acceleration of 1.87 ± 0.47 km/s/yr. This project was completed as part of the NSF REU program at NRAO.
NASA Astrophysics Data System (ADS)
Geng, Lin; Zhang, Xiao-Zheng; Bi, Chuan-Xing
2015-05-01
Time domain plane wave superposition method is extended to reconstruct the transient pressure field radiated by an impacted plate and the normal acceleration of the plate. In the extended method, the pressure measured on the hologram plane is expressed as a superposition of time convolutions between the time-wavenumber normal acceleration spectrum on a virtual source plane and the time domain propagation kernel relating the pressure on the hologram plane to the normal acceleration spectrum on the virtual source plane. By performing an inverse operation, the normal acceleration spectrum on the virtual source plane can be obtained by an iterative solving process, and then taken as the input to reconstruct the whole pressure field and the normal acceleration of the plate. An experiment of a clamped rectangular steel plate impacted by a steel ball is presented. The experimental results demonstrate that the extended method is effective in visualizing the transient vibration and sound radiation of an impacted plate in both time and space domains, thus providing the important information for overall understanding the vibration and sound radiation of the plate.
Concepts for the magnetic design of the MITICA neutral beam test facility ion accelerator.
Chitarin, G; Agostinetti, P; Marconato, N; Marcuzzi, D; Sartori, E; Serianni, G; Sonato, P
2012-02-01
The megavolt ITER injector concept advancement neutral injector test facility will be constituted by a RF-driven negative ion source and by an electrostatic Accelerator, designed to produce a negative Ion with a specific energy up to 1 MeV. The beam is then neutralized in order to obtain a focused 17 MW neutral beam. The magnetic configuration inside the accelerator is of crucial importance for the achievement of a good beam efficiency, with the early deflection of the co-extracted and stripped electrons, and also of the required beam optic quality, with the correction of undesired ion beamlet deflections. Several alternative magnetic design concepts have been considered, comparing in detail the magnetic and beam optics simulation results, evidencing the advantages and drawbacks of each solution both from the physics and engineering point of view.
GPU-accelerated phase extraction algorithm for interferograms: a real-time application
NASA Astrophysics Data System (ADS)
Zhu, Xiaoqiang; Wu, Yongqian; Liu, Fengwei
2016-11-01
Optical testing, having the merits of non-destruction and high sensitivity, provides a vital guideline for optical manufacturing. But the testing process is often computationally intensive and expensive, usually up to a few seconds, which is sufferable for dynamic testing. In this paper, a GPU-accelerated phase extraction algorithm is proposed, which is based on the advanced iterative algorithm. The accelerated algorithm can extract the right phase-distribution from thirteen 1024x1024 fringe patterns with arbitrary phase shifts in 233 milliseconds on average using NVIDIA Quadro 4000 graphic card, which achieved a 12.7x speedup ratio than the same algorithm executed on CPU and 6.6x speedup ratio than that on Matlab using DWANING W5801 workstation. The performance improvement can fulfill the demand of computational accuracy and real-time application.
Flisiak, Robert; Kawazoe, Seiji; Znoyko, Olga; Assy, Nimer; Gadano, Adrian; Kao, Jia-Horng; Lee, Kwan-Sik; Zwirtes, Ricardo; Portsmouth, Simon; Dong, Yuping; Xu, Dong; Kumada, Hiromitsu; Srinivasan, Subasree
2016-11-01
The study objective was to compare the efficacy and safety of peginterferon lambda-1a combined with ribavirin/daclatasvir (Lambda/RBV/DCV), versus peginterferon alfa-2a combined with ribavirin/telaprevir (Alfa/RBV/TVR), in patients chronically infected with hepatitis C virus (HCV), genotype 1b. This was a prospective, randomized, open-label, phase 3 study (NCT01718158) in adults (aged ≥18 years) who were treatment naïve or prior relapsers to peginterferon alfa/ribavirin therapy. The primary endpoint was sustained virologic response at post-treatment follow-up week 12 (SVR12). Patients were randomized in a 2:1 ratio to receive 24 weeks of Lambda/RBV/DCV or response-guided 24 or 48 weeks of Alfa/RBV/TVR. Overall, 440 patients were treated (294 with Lambda/RBV/DCV; 146 with Alfa/RBV/TVR). The proportion of patients achieving SVR12 was 88.8% in the Lambda/RBV/DCV arm and 70.5% in the Alfa/RBV/TVR arm (difference between arms: 18.3%; 95% confidence interval: 9.9-25.7; P < 0.0001). Patients in the Lambda/RBV/DCV group had fewer rash-related adverse events (AEs), cytopenic abnormalities, flu-like symptoms, serious AEs, and discontinuations due to AEs, but more liver abnormalities than those in the Alfa/RBV/TVR group. In conclusion, treatment with Lambda/RBV/DCV led to higher SVR12 rates and a more favorable safety profile than Alfa/RBV/TVR in patients with chronic HCV, genotype 1b infection.
NASA Astrophysics Data System (ADS)
Khairullina, Alphiya Y.; Bui, Lilia; Oleinik, Tatiana V.; Artishevsky, Nelli; Prigoun, Natalia; Sevkovsky, Jakov; Mokhort, Tatiana
1996-12-01
The data bank contains optical, ordinary biochemical and biophysical information on 120 venous blood samples of donors, healthy persons, patients with high pathology, 60 tissue samples. The optical parameters include diffuse reflection R((lambda) ) and transmission T((lambda) ) coefficients for optically thick layers, the absorption K((lambda) ) and extinction (epsilon) ((lambda) ) spectra, oxygenation degree CO2, parameter p determined by sizes and shapes of cells and their aggregates, refractive index of a disperse phase relative to surrounding media, and cooperative effects at high relative concentration. The peculiarities in absorption K((lambda) spectra are connected with different pathologies. It is shown from K((lambda) ) that the grade of pathology connected with the concentration of hemoglobin and mithohondrion together with oxygenation degree of blood and tissues, with the pathological hemoglobin's forms and its decomposition products of different levels. Parameter p is an important diagnostic parameter. We consider that it is necessary to include the oxygenation degree and erythrocyte's aggregation parameter to extend the range of common diagnostic parameters of blood by the first rota.
Nichols, J.D.; Hines, J.E.
2002-01-01
We first consider the estimation of the finite rate of population increase or population growth rate, lambda sub i, using capture-recapture data from open populations. We review estimation and modelling of lambda sub i under three main approaches to modelling open-population data: the classic approach of Jolly (1965) and Seber (1965), the superpopulation approach of Crosbie & Manly (1985) and Schwarz & Arnason (1996), and the temporal symmetry approach of Pradel (1996). Next, we consider the contributions of different demographic components to lambda sub i using a probabilistic approach based on the composition of the population at time i + 1 (Nichols et al., 2000b). The parameters of interest are identical to the seniority parameters, gamma sub i, of Pradel (1996). We review estimation of gamma sub i under the classic, superpopulation, and temporal symmetry approaches. We then compare these direct estimation approaches for lambda sub i and gamma sub i with analogues computed using projection matrix asymptotics. We also discuss various extensions of the estimation approaches to multistate applications and to joint likelihoods involving multiple data types.
NASA Technical Reports Server (NTRS)
Rottman, G. J.; Cebula, R. P.; Gillotay, D.; Simon, P. A.
1996-01-01
This report summarizes the activities of Working Group 2 and Working Group 3 of the SOLax Electromagnetic Radiation Study for Solar Cycle 22 (SOLERS22) Program. The international (SOLERS22) is Project 1.2 of the Solar-Terrestrial Energy Program (STEP) sponsored by SCOSTEP, a committee of the International Council of Scientific Unions). SOLERS22 is comprised of five Working Groups, each concentrating on a specific wave-length range: WG-1 - visible and infrared, WG-2 - mid-ultraviolet (200 < A < 300 nm), WG-3 - Far-ultraviolet (lambda greater than 100 and lambda less than 200 nanometers), WG-4 - extreme-ultraviolet (lambda greater than 10 and lambda less than 100 nm), and WG-5 - X-ray (lambda greater than 1 and lambda less than 10 nano meters). The overarching goals of SOLERS22 are to: 1) establish daily solar irradiance values in the specified wavelength ranges, 2) consider the evolving solar structures as the cause of temporal variations, and 3) understand the underlying physical processes driving these changes.
[Determination of lambda-cyhalothrin residue tea and soil using gas chromatography].
Chen, Linglong; Chen, Jiuxing; Ma, Ming; Chen, Lihua; Yang, Hui; Zhang, Guiqun
2010-08-01
A gas chromatographic (GC) method was established for the determination of lambda-cyhalothrin residue in tea and soil. Tea and soil samples were extracted with hexane, separated by capillary column and determined by gas chromatography-electron capture detector (GC-ECD). The average recoveries of lambda-cyhalothrin in tea and soil were 89.0% - 94.1% and 89.8% - 94.7%, respectively at the spiking levels of 0.02 to 2.00 mg/kg. The corresponding relative standard deviations (RSDs, n = 5) were 3.0% -4.9% and 2.5% -4.2%, respectively. The limit of detection (S/N = 3) was 0.002 mg/kg for lambda-cyhalothrin. The degradations of 2.5% lambda-cyhalothrin microemulsion in tea and soil in Changsha, Hunan were investigated and the degradation equations were Y = 3.199 6e(-0.339 4x) and Y = 0.122 4e(-0.103 6x) with the correlation coefficients of 0.995 6 and 0.924 7, respectively. The half-lives of lambda-cyhalothrin in tea and soil were 2.04 days and 6.69 days, respectively.
An {alpha}-cluster model for {sub {Lambda}}{sup 9}Be spectroscopy
DOE Office of Scientific and Technical Information (OSTI.GOV)
Filikhin, I. N., E-mail: ifilikhin@nccu.edu; Suslov, V. M.; Vlahovic, B.
An {alpha}-cluster model is applied to study low-lying spectrum of the {sub {Lambda}}{sup 9}Be hypernucleus. The three-body {alpha}{alpha}{Lambda} problem is numerically solved by the Faddeev equations in configuration space using phenomenological pair potentials. We found a set of the potentials that reproduces experimental data for the ground state (1/2{sup +}) binding energy and excitation energy of the 5/2{sup +} and 3/2{sup +} states, simultaneously. This set includes the Ali-Bodmer potential of the version 'e' for {alpha}{alpha} and modified Tang-Herndon potential for {alpha}{Lambda} interactions. The spin-orbit {alpha}{Lambda} interaction is given by modified Scheerbaum potential. Low-lying energy levels are evaluated applying amore » variant of the analytical continuation method in the coupling constant. It is shown that the spectral properties of {sub {Lambda}}{sup 9}Be can be classified as an analog of {sup 9}Be spectrum with the exception of several 'genuine hypernuclear states'. This agrees qualitatively with previous studies. The results are compared with experimental data and new interpretation of the spectral structure is discussed.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Xu Weilin; Li Songtao; Zhou Xiaochun
2006-05-07
In the present work a nonmonotonic dependence of standard rate constant (k{sup 0}) on reorganization energy ({lambda}) was discovered qualitatively from electron transfer (Marcus-Hush-Levich) theory for heterogeneous electron transfer processes on electrode surface. It was found that the nonmonotonic dependence of k{sup 0} on {lambda} is another result, besides the disappearance of the famous Marcus inverted region, coming from the continuum of electronic states in electrode: with the increase of {lambda}, the states for both Process I and Process II ET processes all vary from nonadiabatic to adiabatic state continuously, and the {lambda} dependence of k{sup 0} for Process Imore » is monotonic thoroughly, while for Process II on electrode surface the {lambda} dependence of k{sup 0} could show a nonmonotonicity.« less
Shpakovski, G V; Berlin, Y A
1984-01-01
Molecular mechanism of the specialized transducing bacteriophage lambda plac5 formation has been studied. Phage-bacterial DNA junctions in lambda plac5 DNA are localized and primary structure of regions of the abnormal excisional recombination leading to the phage formation is elucidated; the crossover region proved to be comparable with the central part of attP and attB sites (the core and the adjacent tetranucleotide) in length and degree of homology. Bacterial insert in lambda plac5 DNA is shown to end immediately after Z-Y spacer, the DNA not containing lacY gene segments. The data obtained led to the conclusion of site-specific (homologous) character of abnormal excision upon formation of lambda transducing bacteriophages. Possible mechanisms of the excision are discussed. Images PMID:6091038
Differential Photoproduction Cross Sections of the Sigma0(1385), Lambda(1405), and Lambda(1520)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Moriya, Kei; Schumacher, Reinhard A.
2013-10-01
We report the exclusive photoproduction cross sections for the Sigma(1385), Lambda(1405), and Lambda(1520) in the reactions gamma + p -> K+ + Y* using the CLAS detector for energies from near the respective production thresholds up to a center-of-mass energy W of 2.85 GeV. The differential cross sections are integrated to give the total exclusive cross sections for each hyperon. Comparisons are made to current theoretical models based on the effective Lagrangian approach and fitted to previous data. The accuracy of these models is seen to vary widely. The cross sections for the Lambda(1405) region are strikingly different for themore » Sigma+pi-, Sigma0 pi0, and Sigma- pi+ decay channels, indicating the effect of isospin interference, especially at W values close to the threshold.« less
Global adjoint tomography: First-generation model
Bozdag, Ebru; Peter, Daniel; Lefebvre, Matthieu; ...
2016-09-22
We present the first-generation global tomographic model constructed based on adjoint tomography, an iterative full-waveform inversion technique. Synthetic seismograms were calculated using GPU-accelerated spectral-element simulations of global seismic wave propagation, accommodating effects due to 3-D anelastic crust & mantle structure, topography & bathymetry, the ocean load, ellipticity, rotation, and self-gravitation. Fréchet derivatives were calculated in 3-D anelastic models based on an adjoint-state method. The simulations were performed on the Cray XK7 named ‘Titan’, a computer with 18 688 GPU accelerators housed at Oak Ridge National Laboratory. The transversely isotropic global model is the result of 15 tomographic iterations, which systematicallymore » reduced differences between observed and simulated three-component seismograms. Our starting model combined 3-D mantle model S362ANI with 3-D crustal model Crust2.0. We simultaneously inverted for structure in the crust and mantle, thereby eliminating the need for widely used ‘crustal corrections’. We used data from 253 earthquakes in the magnitude range 5.8 ≤ M w ≤ 7.0. We started inversions by combining ~30 s body-wave data with ~60 s surface-wave data. The shortest period of the surface waves was gradually decreased, and in the last three iterations we combined ~17 s body waves with ~45 s surface waves. We started using 180 min long seismograms after the 12th iteration and assimilated minor- and major-arc body and surface waves. The 15th iteration model features enhancements of well-known slabs, an enhanced image of the Samoa/Tahiti plume, as well as various other plumes and hotspots, such as Caroline, Galapagos, Yellowstone and Erebus. Furthermore, we see clear improvements in slab resolution along the Hellenic and Japan Arcs, as well as subduction along the East of Scotia Plate, which does not exist in the starting model. Point-spread function tests demonstrate that we are approaching the resolution of continental-scale studies in some areas, for example, underneath Yellowstone. Here, this is a consequence of our multiscale smoothing strategy in which we define our smoothing operator as a function of the approximate Hessian kernel, thereby smoothing gradients less wherever we have good ray coverage, such as underneath North America.« less
Global adjoint tomography: First-generation model
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bozdag, Ebru; Peter, Daniel; Lefebvre, Matthieu
We present the first-generation global tomographic model constructed based on adjoint tomography, an iterative full-waveform inversion technique. Synthetic seismograms were calculated using GPU-accelerated spectral-element simulations of global seismic wave propagation, accommodating effects due to 3-D anelastic crust & mantle structure, topography & bathymetry, the ocean load, ellipticity, rotation, and self-gravitation. Fréchet derivatives were calculated in 3-D anelastic models based on an adjoint-state method. The simulations were performed on the Cray XK7 named ‘Titan’, a computer with 18 688 GPU accelerators housed at Oak Ridge National Laboratory. The transversely isotropic global model is the result of 15 tomographic iterations, which systematicallymore » reduced differences between observed and simulated three-component seismograms. Our starting model combined 3-D mantle model S362ANI with 3-D crustal model Crust2.0. We simultaneously inverted for structure in the crust and mantle, thereby eliminating the need for widely used ‘crustal corrections’. We used data from 253 earthquakes in the magnitude range 5.8 ≤ M w ≤ 7.0. We started inversions by combining ~30 s body-wave data with ~60 s surface-wave data. The shortest period of the surface waves was gradually decreased, and in the last three iterations we combined ~17 s body waves with ~45 s surface waves. We started using 180 min long seismograms after the 12th iteration and assimilated minor- and major-arc body and surface waves. The 15th iteration model features enhancements of well-known slabs, an enhanced image of the Samoa/Tahiti plume, as well as various other plumes and hotspots, such as Caroline, Galapagos, Yellowstone and Erebus. Furthermore, we see clear improvements in slab resolution along the Hellenic and Japan Arcs, as well as subduction along the East of Scotia Plate, which does not exist in the starting model. Point-spread function tests demonstrate that we are approaching the resolution of continental-scale studies in some areas, for example, underneath Yellowstone. Here, this is a consequence of our multiscale smoothing strategy in which we define our smoothing operator as a function of the approximate Hessian kernel, thereby smoothing gradients less wherever we have good ray coverage, such as underneath North America.« less
The lambda sign: a new radiographic indicator of latent syndesmosis instability.
Ryan, Ltc Paul; Hills, Maj Chad; Chang, James; Wilson, Cpt David
2014-09-01
Latent syndesmotic instability is a common cause of chronic ankle pain. The diagnosis is not readily apparent on static imaging as the fibula remains reduced. The hypothesis of this study was that a previously undescribed novel finding on coronal MRI (lambda sign) is an independent indicator of latent syndesmosis instability. We also report on the utility of classic radiographic and physical exam findings. A total of 23 patients with latent syndesmotic instability diagnosed via arthroscopy (group I) were compared to a cohort of 40 patients who were found to have a stable syndesmosis during arthroscopy for unrelated conditions (group II). A retrospective chart review was performed evaluating their clinical history, preoperative physical examination, and radiologic findings. The lambda sign is a high intensity signal seen on coronal MR imaging that resembles the Greek letter lambda. All of the physical exam findings tested were statistically significant. Pain at the syndesmosis had the highest sensitivity (83%), while pain reproduced with the proximal squeeze test resulted in the highest specificity (89%). The external rotation stress test had the highest positive predictive value (75%). Of the radiographic examinations performed, only the lambda sign was found to have statistical significance with a sensitivity of 75% and a specificity of 63%. The presence of a lambda sign on the MRI of patients with physical exam findings suggestive of syndesmotic pain was highly sensitive (75%) and specific (85%). The lambda sign noted on the coronal MRI was both sensitive and specific for injuries involving greater than 2 mm of diastasis on arthroscopic stress examination of the syndesmosis. While neither the lambda sign nor any other finding on physical or radiographic examination represented an independent predictor of syndesmotic instability, the presence of a lambda sign in concert with positive physical exam findings might help health care providers determine which patients might benefit from operative intervention or referral. Level III, case control study. © The Author(s) 2014.
A reanalysis of the SWP-HI IUE observations of Capella
NASA Technical Reports Server (NTRS)
Wood, Brian E.; Ayres, T. R.
1995-01-01
We have reanalyzed the numerous high-resolution, far-ultraviolet observations of Capella made by the International Ultraviolet Explorer (IUE) in its 16 yr lifetime. Our purpose was to search for long-term profile variations in Capella's ultraviolet emission lines and to complement the analysis of Goddard High Resolution Spectrograph (GHRS) observations of Capella, discussed in a companion paper (Linsky et al. 1995). We implemented a state-of-the-art photometric correction and spectral extraction procedure to improve S/N and control potential sources for systematic errors. Nevertheless, we were unable to find compelling evidence for any significant long-term profile variations. Previous work has shown that the G8 primary star is only a minor contributor to the high-excitation transition region lines but is a significant contributor to the low-excitation chromospheric lines. We have found exceptions to this rule, however. We find that the G8 star is responsible for a significant portion of Capella's N V lambda lambda 1239, 1243 emission, but is not a large contributor to the S I lambda 1296, Cl I lambda 1352, and O lambda 1356 lines. We suggest possible explanations for these behaviors. We also find evidence that the He II lambda 1640 emission from the G1 star is from the transition region, while the He II lambda 1640 emission from the G8 star is chromospheric, consistent with the findings of Linsky et al. (1994). The C II lambda 1336 line shows a weak central reversal. It is blueshifted by about 9 km/s with respect to the centroid of the emission from the G1 star. While the central reversal of the C II line is blueshifted by about 9 km/s with respect to the centroid of the emission from the G1 star. While the central reversal of the C II line is blueshifted, the central reversal of the Si III lambda 1207 line discussed by Linsky et al. (1994) is not.
NASA Technical Reports Server (NTRS)
Zheng, W.; Kriss, G. A.; Wang, J. X.; Brotherton, M.; Oegerle, W. R.; Blair, W. P.; Davidsen, A. F.; Green, R. F.; Hutchings, J. B.; Kaiser, M. E.;
2001-01-01
We present a moderate-resolution (approximately 20 km s(exp -1) spectrum of the mini broad absorption line QSO PG 1351+64 between 915-1180 A, obtained with the Far Ultraviolet Spectroscopic Explorer (FUSE). Additional low-resolution spectra at longer wavelengths were also obtained with the Hubble Space Telescope (HST) and ground-based telescopes. Broad absorption is present on the blue wings of C III (lambda)977, Ly(beta), O VI (lambda)(lambda)1032,1038, Ly(alpha), N V (lambda)(lambda)1238,1242, Si IV (lambda)(lambda)1393,1402, and C IV (lambda)(lambda)1548,1450. The absorption profile can be fitted with five components at velocities of approximately -780, -1049, -1629, -1833, and -3054 km s(exp -1) with respect to the emission-line redshift of z = 0.088. All the absorption components cover a large fraction of the continuum source as well as the broad-line region. The O VI emission feature is very weak, and the O VI/Ly(alpha) flux ratio is 0.08, one of the lowest among low-redshift active galaxies and QSOs. The UV (ultraviolet) continuum shows a significant change in slope near 1050 A in the restframe. The steeper continuum shortward of the Lyman limit extrapolates well to the observed weak X-ray flux level. The absorbers' properties are similar to those of high-redshift broad absorption-line QSOs. The derived total column density of the UV absorbers is on the order of 10(exp 21) cm(exp -2), unlikely to produce significant opacity above 1 keV in the X-ray. Unless there is a separate, high-ionization X-ray absorber, the QSO's weak X-ray flux may be intrinsic. The ionization level of the absorbing components is comparable to that anticipated in the broad-line region, therefore the absorbers may be related to broad-line clouds along the line of sight.
NASA Technical Reports Server (NTRS)
Zheng, W.; Kriss, G. A.; Wang, J. X.; Brotherton, M.; Oegerle, W. R.; Blair, W. P.; Davidsen, A. F.; Green, R. F.; Hutchings, J. B.; Kaiser, M. E.;
2001-01-01
We present a moderate-resolution (approximately 20 km/s) spectrum of the broad-absorption line QSO PG 1351+64 between 915-1180 angstroms, obtained with the Far Ultraviolet Spectroscopic Explorer (FUSE). Additional low-resolution spectra at longer wavelengths were also obtained with the Hubble Space Telescope (HST) and ground-based telescopes. Broad absorption is present on the blue wings of C III lambda977, Ly-beta, O VI lambda-lambda-1032,1038, Ly-alpha, N V lambda-lambda-1238,1242, Si IV lambda-lambda-1393,1402, and C IV lambda-lambda-1548,1450. The absorption profile can be fitted with five components at velocities of approximately -780, -1049, -1629, -1833, and -3054 km/s with respect to the emission-line redshift of z = 0.088. All the absorption components cover a large fraction of the continuum source as well as the broad-line region. The O VI emission feature is very weak, and the O VI/Ly-alpha flux ratio is 0.08, one of the lowest among low-redshift active galaxies and QSOs. The ultraviolet continuum shows a significant change in slope near 1050 angstroms in the restframe. The steeper continuum shortward of the Lyman limit extrapolates well to the observed weak X-ray flux level. The absorbers' properties are similar to those of high-redshift broad absorption-line QSOs. The derived total column density of the UV absorbers is on the order of 10(exp 21)/s, unlikely to produce significant opacity above 1 keV in the X-ray. Unless there is a separate, high-ionization X-ray absorber, the QSO's weak X-ray flux may be intrinsic. The ionization level of the absorbing components is comparable to that anticipated in the broad-line region, therefore the absorbers may be related to broad-line clouds along the line of sight.
Acceleration of electrons and ions by strong lower-hybrid turbulence in solar flares
NASA Technical Reports Server (NTRS)
Spicer, D. S.; Bingham, R.; Su, J. J.; Shapiro, V. D.; Shevchenko, V.; Ma, S.; Dawson, J. M.; Mcclements, K. G.
1994-01-01
One of the outstanding problems in solar flare theory is how to explain the 10-20 keV and greater hard x-ray emissions by a thick target bremsstrahlung model. The model requires the acceleration mechanism to accelerate approximately 10(exp 35) electrons sec(exp -l) with comparable energies, without producing a large return current which persists for long time scales after the beam ceases to exist due to Lenz's law, thereby, producing a self-magnetic field of order a few mega-Gauss. In this paper, we investigate particle acceleration resulting from the relaxation of unstable ion ring distributions, producing strong wave activity at the lower hybrid frequency. It is shown that strong lower hybrid wave turbulence collapses in configuration space producing density cavities containing intense electrostatic lower hybrid wave activity. The collapse of these intense nonlinear wave packets saturate by particle acceleration producing energetic electron and ion tails. There are several mechanisms whereby unstable ion distributions could be formed in the solar atmosphere, including reflection at perpendicular shocks, tearing modes, and loss cone depletion. Numerical simulations of ion ring relaxation processes, obtained using a 2 1/2-D fully electromagnetic, relativistic particle in cell code are discussed. We apply the results to the problem of explaining energetic particle production in solar flares. The results show the simultaneous acceleration of both electrons and ions to very high energies: electrons are accelerated to energies in the range 10-500 keV, while ions are accelerated to energies of the order of MeVs, giving rise to x-ray emission and gamma-ray emission respectively. Our simulations also show wave generation at the electron cyclotron frequency. We suggest that these waves are the solar millisecond radio spikes. The strong turbulence collapse process leads to a highly filamented plasma producing many localized regions for particle acceleration and resulting in approximately 10(exp 17) electron 'beamlets' of width approximately equal to 10 lambda sub De which eliminates the production of large magnetic fields. In this paper, we demonstrate that the model produces an energetic electron spectrum with the right flux to account for the hard x-ray observations.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bogolyubskii-breve, M.Y.; Vinitskii-breve, A.A.; Ermolov, P.F.
1986-05-01
Inclusive and semi-inclusive ..lambda..-hyperon spectra in p-barp interactions at 32 GeV/c are presented. The processes whereby ..lambda.. hyperons are produced in various channels are analyzed by comparison with the predictions of the Lund model and with dual-topological-unitarization (DTU)-based models. The ..lambda..-hyperon characteristics differ from those predicted in the Lund model. The main cause of the differences is that multiple production of particles is represented in this model in terms of breaking of one string, thereby excluding correlation effects between the vertices.
Kato type operators and Weyl's theorem
NASA Astrophysics Data System (ADS)
Duggal, B. P.; Djordjevic, S. V.; Kubrusly, Carlos
2005-09-01
A Banach space operator T satisfies Weyl's theorem if and only if T or T* has SVEP at all complex numbers [lambda] in the complement of the Weyl spectrum of T and T is Kato type at all [lambda] which are isolated eigenvalues of T of finite algebraic multiplicity. If T* (respectively, T) has SVEP and T is Kato type at all [lambda] which are isolated eigenvalues of T of finite algebraic multiplicity (respectively, T is Kato type at all [lambda][set membership, variant]iso[sigma](T)), then T satisfies a-Weyl's theorem (respectively, T* satisfies a-Weyl's theorem).
Assessments of fluid friction factors for use in leak rate calculations
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chivers, T.C.
1997-04-01
Leak before Break procedures require estimates of leakage, and these in turn need fluid friction to be assessed. In this paper available data on flow rates through idealized and real crack geometries are reviewed in terms of a single friction factor k It is shown that for {lambda} < 1 flow rates can be bounded using correlations in terms of surface R{sub a} values. For {lambda} > 1 the database is less precise, but {lambda} {approx} 4 is an upper bound, hence in this region flow calculations can be assessed using 1 < {lambda} < 4.
Geometrical interpretation for the outer SU(3) outer multiplicity label
NASA Technical Reports Server (NTRS)
Draayer, Jerry P.; Troltenier, D.
1995-01-01
A geometrical interpretation for the outer multiplicity rho that occurs in a reduction of the product of two SU(3) representations, (lambda(sub pi), mu(sub pi)) x (lambda(sub nu), mu(sub nu)) approaches sigma(sub rho)(lambda, mu)(sub rho), is introduced. This coupling of proton (pi) and neutron (nu) representations arises, for example, in both boson and fermion descriptions of heavy deformed nuclei. Attributing a geometry to the coupling raises the possibility of introducing a simple interaction that provides a physically meaningful way for distinguishing multiple occurrences of (lambda, mu) values that can arise in such products.
Seismic Design of ITER Component Cooling Water System-1 Piping
NASA Astrophysics Data System (ADS)
Singh, Aditya P.; Jadhav, Mahesh; Sharma, Lalit K.; Gupta, Dinesh K.; Patel, Nirav; Ranjan, Rakesh; Gohil, Guman; Patel, Hiren; Dangi, Jinendra; Kumar, Mohit; Kumar, A. G. A.
2017-04-01
The successful performance of ITER machine very much depends upon the effective removal of heat from the in-vessel components and other auxiliary systems during Tokamak operation. This objective will be accomplished by the design of an effective Cooling Water System (CWS). The optimized piping layout design is an important element in CWS design and is one of the major design challenges owing to the factors of large thermal expansion and seismic accelerations; considering safety, accessibility and maintainability aspects. An important sub-system of ITER CWS, Component Cooling Water System-1 (CCWS-1) has very large diameter of pipes up to DN1600 with many intersections to fulfill the process flow requirements of clients for heat removal. Pipe intersection is the weakest link in the layout due to high stress intensification factor. CCWS-1 piping up to secondary confinement isolation valves as well as in-between these isolation valves need to survive a Seismic Level-2 (SL-2) earthquake during the Tokamak operation period to ensure structural stability of the system in the Safe Shutdown Earthquake (SSE) event. This paper presents the design, qualification and optimization of layout of ITER CCWS-1 loop to withstand SSE event combined with sustained and thermal loads as per the load combinations defined by ITER and allowable limits as per ASME B31.3, This paper also highlights the Modal and Response Spectrum Analyses done to find out the natural frequency and system behavior during the seismic event.
Iterative near-term ecological forecasting: Needs, opportunities, and challenges
Dietze, Michael C.; Fox, Andrew; Beck-Johnson, Lindsay; Betancourt, Julio L.; Hooten, Mevin B.; Jarnevich, Catherine S.; Keitt, Timothy H.; Kenney, Melissa A.; Laney, Christine M.; Larsen, Laurel G.; Loescher, Henry W.; Lunch, Claire K.; Pijanowski, Bryan; Randerson, James T.; Read, Emily; Tredennick, Andrew T.; Vargas, Rodrigo; Weathers, Kathleen C.; White, Ethan P.
2018-01-01
Two foundational questions about sustainability are “How are ecosystems and the services they provide going to change in the future?” and “How do human decisions affect these trajectories?” Answering these questions requires an ability to forecast ecological processes. Unfortunately, most ecological forecasts focus on centennial-scale climate responses, therefore neither meeting the needs of near-term (daily to decadal) environmental decision-making nor allowing comparison of specific, quantitative predictions to new observational data, one of the strongest tests of scientific theory. Near-term forecasts provide the opportunity to iteratively cycle between performing analyses and updating predictions in light of new evidence. This iterative process of gaining feedback, building experience, and correcting models and methods is critical for improving forecasts. Iterative, near-term forecasting will accelerate ecological research, make it more relevant to society, and inform sustainable decision-making under high uncertainty and adaptive management. Here, we identify the immediate scientific and societal needs, opportunities, and challenges for iterative near-term ecological forecasting. Over the past decade, data volume, variety, and accessibility have greatly increased, but challenges remain in interoperability, latency, and uncertainty quantification. Similarly, ecologists have made considerable advances in applying computational, informatic, and statistical methods, but opportunities exist for improving forecast-specific theory, methods, and cyberinfrastructure. Effective forecasting will also require changes in scientific training, culture, and institutions. The need to start forecasting is now; the time for making ecology more predictive is here, and learning by doing is the fastest route to drive the science forward.
Iterative near-term ecological forecasting: Needs, opportunities, and challenges.
Dietze, Michael C; Fox, Andrew; Beck-Johnson, Lindsay M; Betancourt, Julio L; Hooten, Mevin B; Jarnevich, Catherine S; Keitt, Timothy H; Kenney, Melissa A; Laney, Christine M; Larsen, Laurel G; Loescher, Henry W; Lunch, Claire K; Pijanowski, Bryan C; Randerson, James T; Read, Emily K; Tredennick, Andrew T; Vargas, Rodrigo; Weathers, Kathleen C; White, Ethan P
2018-02-13
Two foundational questions about sustainability are "How are ecosystems and the services they provide going to change in the future?" and "How do human decisions affect these trajectories?" Answering these questions requires an ability to forecast ecological processes. Unfortunately, most ecological forecasts focus on centennial-scale climate responses, therefore neither meeting the needs of near-term (daily to decadal) environmental decision-making nor allowing comparison of specific, quantitative predictions to new observational data, one of the strongest tests of scientific theory. Near-term forecasts provide the opportunity to iteratively cycle between performing analyses and updating predictions in light of new evidence. This iterative process of gaining feedback, building experience, and correcting models and methods is critical for improving forecasts. Iterative, near-term forecasting will accelerate ecological research, make it more relevant to society, and inform sustainable decision-making under high uncertainty and adaptive management. Here, we identify the immediate scientific and societal needs, opportunities, and challenges for iterative near-term ecological forecasting. Over the past decade, data volume, variety, and accessibility have greatly increased, but challenges remain in interoperability, latency, and uncertainty quantification. Similarly, ecologists have made considerable advances in applying computational, informatic, and statistical methods, but opportunities exist for improving forecast-specific theory, methods, and cyberinfrastructure. Effective forecasting will also require changes in scientific training, culture, and institutions. The need to start forecasting is now; the time for making ecology more predictive is here, and learning by doing is the fastest route to drive the science forward.
NASA Astrophysics Data System (ADS)
Yuan, Jian-guo; Tong, Qing-zhen; Huang, Sheng; Wang, Yong
2013-11-01
An effective hierarchical reliable belief propagation (HRBP) decoding algorithm is proposed according to the structural characteristics of systematically constructed Gallager low-density parity-check (SCG-LDPC) codes. The novel decoding algorithm combines the layered iteration with the reliability judgment, and can greatly reduce the number of the variable nodes involved in the subsequent iteration process and accelerate the convergence rate. The result of simulation for SCG-LDPC(3969,3720) code shows that the novel HRBP decoding algorithm can greatly reduce the computing amount at the condition of ensuring the performance compared with the traditional belief propagation (BP) algorithm. The bit error rate (BER) of the HRBP algorithm is considerable at the threshold value of 15, but in the subsequent iteration process, the number of the variable nodes for the HRBP algorithm can be reduced by about 70% at the high signal-to-noise ratio (SNR) compared with the BP algorithm. When the threshold value is further increased, the HRBP algorithm will gradually degenerate into the layered-BP algorithm, but at the BER of 10-7 and the maximal iteration number of 30, the net coding gain (NCG) of the HRBP algorithm is 0.2 dB more than that of the BP algorithm, and the average iteration times can be reduced by about 40% at the high SNR. Therefore, the novel HRBP decoding algorithm is more suitable for optical communication systems.
Image transmission system using adaptive joint source and channel decoding
NASA Astrophysics Data System (ADS)
Liu, Weiliang; Daut, David G.
2005-03-01
In this paper, an adaptive joint source and channel decoding method is designed to accelerate the convergence of the iterative log-dimain sum-product decoding procedure of LDPC codes as well as to improve the reconstructed image quality. Error resilience modes are used in the JPEG2000 source codec, which makes it possible to provide useful source decoded information to the channel decoder. After each iteration, a tentative decoding is made and the channel decoded bits are then sent to the JPEG2000 decoder. Due to the error resilience modes, some bits are known to be either correct or in error. The positions of these bits are then fed back to the channel decoder. The log-likelihood ratios (LLR) of these bits are then modified by a weighting factor for the next iteration. By observing the statistics of the decoding procedure, the weighting factor is designed as a function of the channel condition. That is, for lower channel SNR, a larger factor is assigned, and vice versa. Results show that the proposed joint decoding methods can greatly reduce the number of iterations, and thereby reduce the decoding delay considerably. At the same time, this method always outperforms the non-source controlled decoding method up to 5dB in terms of PSNR for various reconstructed images.
Biaz, A; Uwingabiye, J; Rachid, A; Dami, A; Bouhsain, S; Ouzzif, Z; Idrissi, S El Machtani
2018-06-01
We report a case of immunoglobulin (Ig) D myeloma with hidden lambda light chains in a patient whose immunofixation test was very difficult to interpret: the IgD reacts with the anti-δ heavy chain antiserum but does not react with anti-lambda antiserum. The band in the D heavy chain lane is unmatched in light chain lanes and the band in lambda light chain lane migrates higher. To distinguish between heavy chain disease and immunoglobulin with "hidden" light chains, the sample was exposed to a very high concentration of anti-lambda and anti-kappa antisera for 48 hours. The serum immunofixation test of the sample treated with anti-lambda showed a decrease in the intensity of the band corresponding to D heavy chain lane as well as the modification of its mobility confirming the presence of IgD with the hidden lambda light chains. The IgD myeloma with hidden light chains remains a rare entity, hence the interest of sensitizing health professionals to be vigilant and ensure a good diagnosis. The proposed technique is useful, simple, reliable, and less laborious than those previous reported in the literature. Medical laboratories using Sebia-Hydrasys® system should be aware of the described phenomenon in order to avoid identifying an IgD myeloma as a delta heavy chain disease.
Perturbation theory corrections to the two-particle reduced density matrix variational method.
Juhasz, Tamas; Mazziotti, David A
2004-07-15
In the variational 2-particle-reduced-density-matrix (2-RDM) method, the ground-state energy is minimized with respect to the 2-particle reduced density matrix, constrained by N-representability conditions. Consider the N-electron Hamiltonian H(lambda) as a function of the parameter lambda where we recover the Fock Hamiltonian at lambda=0 and we recover the fully correlated Hamiltonian at lambda=1. We explore using the accuracy of perturbation theory at small lambda to correct the 2-RDM variational energies at lambda=1 where the Hamiltonian represents correlated atoms and molecules. A key assumption in the correction is that the 2-RDM method will capture a fairly constant percentage of the correlation energy for lambda in (0,1] because the nonperturbative 2-RDM approach depends more significantly upon the nature rather than the strength of the two-body Hamiltonian interaction. For a variety of molecules we observe that this correction improves the 2-RDM energies in the equilibrium bonding region, while the 2-RDM energies at stretched or nearly dissociated geometries, already highly accurate, are not significantly changed. At equilibrium geometries the corrected 2-RDM energies are similar in accuracy to those from coupled-cluster singles and doubles (CCSD), but at nonequilibrium geometries the 2-RDM energies are often dramatically more accurate as shown in the bond stretching and dissociation data for water and nitrogen. (c) 2004 American Institute of Physics.
Farmer, D; Hill, I R; Maund, S J
1995-08-01
: The fate and effects of two pyrethroid insecticides (lambda-cyhalothrin and cypermethrin) were investigated in replicated 25 m(3) pond mesocosms. Three pesticide treatments which simulated spray drift deposition were examined: 0.7 g a.i. ha(-1) cypermethrin and 0.17 and 1.7 g a.i. ha(-1) lambda-cyhalothrin. Based on the use rate and pesticidal activity of the chemicals, the cypermethrin and lower lambda-cyhalothrin rates were approximately equivalent. After applications, pyrethroid residues in the water column declined rapidly. Treatment-related effects were observed on some macroinvertebrate taxa, most notably the Asellidae and Gammaridae. Surfacedwelling insects also suffered initial knock-down, particularly in the 1.7 g a.i. ha(-1) lambda-cyhalothrin treatment, but there was recovery after the spray period. No adverse effects occurred on algae, macrophytes or zooplankton, but there were occasional enhancements (e.g. algal biomass and abundances of copepod nauplii and Rotifera) which may have been indirect effects. An overall comparison of the treatments indicated that the higher lambda-cyhalothrin rate had the greatest effects, whilst the cypermethrin application had a somewhat greater impact than the lower lambda-cyhalothrin treatment rate (due to effects on peracarid crustaceans). The study indicated that should spray drift occur at the levels expected for either pyrethroid's normal use patterns, potential impacts on natural aquatic ecosystems would be minor and transient.
ERIC Educational Resources Information Center
Woodruff, David; Wu, Yi-Fang
2012-01-01
The purpose of this paper is to illustrate alpha's robustness and usefulness, using actual and simulated educational test data. The sampling properties of alpha are compared with the sampling properties of several other reliability coefficients: Guttman's lambda[subscript 2], lambda[subscript 4], and lambda[subscript 6]; test-retest reliability;…
Development of iterative techniques for the solution of unsteady compressible viscous flows
NASA Technical Reports Server (NTRS)
Sankar, Lakshmi; Hixon, Duane
1993-01-01
The work done under this project was documented in detail as the Ph. D. dissertation of Dr. Duane Hixon. The objectives of the research project were evaluation of the generalized minimum residual method (GMRES) as a tool for accelerating 2-D and 3-D unsteady flows and evaluation of the suitability of the GMRES algorithm for unsteady flows, computed on parallel computer architectures.
Systems Engineering of Electric and Hybrid Vehicles
NASA Technical Reports Server (NTRS)
Kurtz, D. W.; Levin, R. R.
1986-01-01
Technical paper notes systems engineering principles applied to development of electric and hybrid vehicles such that system performance requirements support overall program goal of reduced petroleum consumption. Paper discusses iterative design approach dictated by systems analyses. In addition to obvious peformance parameters of range, acceleration rate, and energy consumption, systems engineering also considers such major factors as cost, safety, reliability, comfort, necessary supporting infrastructure, and availability of materials.
Wang, Chunhao; Yin, Fang-Fang; Kirkpatrick, John P; Chang, Zheng
2017-08-01
To investigate the feasibility of using undersampled k-space data and an iterative image reconstruction method with total generalized variation penalty in the quantitative pharmacokinetic analysis for clinical brain dynamic contrast-enhanced magnetic resonance imaging. Eight brain dynamic contrast-enhanced magnetic resonance imaging scans were retrospectively studied. Two k-space sparse sampling strategies were designed to achieve a simulated image acquisition acceleration factor of 4. They are (1) a golden ratio-optimized 32-ray radial sampling profile and (2) a Cartesian-based random sampling profile with spatiotemporal-regularized sampling density constraints. The undersampled data were reconstructed to yield images using the investigated reconstruction technique. In quantitative pharmacokinetic analysis on a voxel-by-voxel basis, the rate constant K trans in the extended Tofts model and blood flow F B and blood volume V B from the 2-compartment exchange model were analyzed. Finally, the quantitative pharmacokinetic parameters calculated from the undersampled data were compared with the corresponding calculated values from the fully sampled data. To quantify each parameter's accuracy calculated using the undersampled data, error in volume mean, total relative error, and cross-correlation were calculated. The pharmacokinetic parameter maps generated from the undersampled data appeared comparable to the ones generated from the original full sampling data. Within the region of interest, most derived error in volume mean values in the region of interest was about 5% or lower, and the average error in volume mean of all parameter maps generated through either sampling strategy was about 3.54%. The average total relative error value of all parameter maps in region of interest was about 0.115, and the average cross-correlation of all parameter maps in region of interest was about 0.962. All investigated pharmacokinetic parameters had no significant differences between the result from original data and the reduced sampling data. With sparsely sampled k-space data in simulation of accelerated acquisition by a factor of 4, the investigated dynamic contrast-enhanced magnetic resonance imaging pharmacokinetic parameters can accurately estimate the total generalized variation-based iterative image reconstruction method for reliable clinical application.
Tritium proof-of-principle pellet injector: Phase 2
NASA Astrophysics Data System (ADS)
Fisher, P. W.; Gouge, M. J.
1995-03-01
As part of the International Thermonuclear Engineering Reactor (ITER) plasma fueling development program, Oak Ridge National Laboratory (ORNL) has fabricated a pellet injection system to test the mechanical and thermal properties of extruded tritium. This repeating, single-stage, pneumatic injector, called the Tritium-Proof-of-Principle Phase-2 (TPOP-2) Pellet Injector, has a piston-driven mechanical extruder and is designed to extrude hydrogenic pellets sized for the ITER device. The TPOP-II program has the following development goals: evaluate the feasibility of extruding tritium and DT mixtures for use in future pellet injection systems; determine the mechanical and thermal properties of tritium and DT extrusions; integrate, test and evaluate the extruder in a repeating, single-stage light gas gun sized for the ITER application (pellet diameter approximately 7-8 mm); evaluate options for recycling propellant and extruder exhaust gas; evaluate operability and reliability of ITER prototypical fueling systems in an environment of significant tritium inventory requiring secondary and room containment systems. In initial tests with deuterium feed at ORNL, up to thirteen pellets have been extruded at rates up to 1 Hz and accelerated to speeds of order 1.0-1.1 km/s using hydrogen propellant gas at a supply pressure of 65 bar. The pellets are typically 7.4 mm in diameter and up to 11 mm in length and are the largest cryogenic pellets produced by the fusion program to date. These pellets represent about a 11% density perturbation to ITER. Hydrogenic pellets will be used in ITER to sustain the fusion power in the plasma core and may be crucial in reducing first wall tritium inventories by a process called isotopic fueling where tritium-rich pellets fuel the burning plasma core and deuterium gas fuels the edge.
Townsend, Catherine L; Laffy, Julie M J; Wu, Yu-Chang Bryan; Silva O'Hare, Joselli; Martin, Victoria; Kipling, David; Fraternali, Franca; Dunn-Walters, Deborah K
2016-01-01
Antibody variable regions are composed of a heavy and a light chain, and in humans, there are two light chain isotypes: kappa and lambda. Despite their importance in receptor editing, the light chain is often overlooked in the antibody literature, with the focus being on the heavy chain complementarity-determining region (CDR)-H3 region. In this paper, we set out to investigate the physicochemical and structural differences between human kappa and lambda light chain CDR regions. We constructed a dataset containing over 29,000 light chain variable region sequences from IgM-transcribing, newly formed B cells isolated from human bone marrow and peripheral blood. We also used a published human naïve dataset to investigate the CDR-H3 properties of heavy chains paired with kappa and lambda light chains and probed the Protein Data Bank to investigate the structural differences between kappa and lambda antibody CDR regions. We found that kappa and lambda light chains have very different CDR physicochemical and structural properties, whereas the heavy chains with which they are paired do not differ significantly. We also observed that the mean CDR3 N nucleotide addition in the kappa, lambda, and heavy chain gene rearrangements are correlated within donors but can differ between donors. This indicates that terminal deoxynucleotidyl transferase may work with differing efficiencies between different people but the same efficiency in the different classes of immunoglobulin chain within one person. We have observed large differences in the physicochemical and structural properties of kappa and lambda light chain CDR regions. This may reflect different roles in the humoral immune response.
Hruska, Matthew W; Adamczyk, Robert; Colston, Elizabeth; Hesney, Michael; Stonier, Michele; Myler, Heather; Bertz, Richard
2015-09-01
This open label study was conducted to assess the effect of renal impairment (RI) on the pharmacokinetics (PK) of peginterferon lambda-1a (Lambda). Subjects (age 18-75 years, BMI 18-35 kg m(-2) ) were enrolled into one of five renal function groups: normal (n = 12), mild RI (n = 8), moderate RI (n = 8), severe RI (n = 7), end-stage renal disease (ESRD, n = 8) based on estimated glomerular filtration rate (eGFR) calculated using the Modification of Diet in Renal Disease (MDRD) equation. Subjects received a single dose of Lambda (180 µg) subcutaneously on day 1 followed by PK serum sample collections through day 29. Safety, tolerability and immunogenicity data were collected through day 43. PK parameters were estimated and summarized by group. Geometric mean ratios (GMR) and 90% confidence intervals (CIs) were calculated between normal and RI groups. With decreasing eGFR, Lambda exposure (Cmax , AUC) increased while apparent clearance (CL/F) and apparent volume of distribution (V/F) decreased. Relative to subjects with normal renal function (geometric mean AUC = 99.5 ng ml(-1) h), Lambda exposure estimates (AUC) were slightly increased in the mild RI group (geometric mean [90% CI]: 1.20 [0.82, 1.77]) and greater in the moderate (1.95 [1.35, 2.83]), severe RI (1.95 [1.30, 2.93]) and ESRD (1.88 [1.30, 2.73]) groups. Lambda was generally well tolerated. The results demonstrated that RI reduces the clearance of Lambda and suggests that dose modifications may not be required in patients with mild RI but may be required in patients with moderate to severe RI or ESRD. © 2015 The British Pharmacological Society.
Townsend, Catherine L.; Laffy, Julie M. J.; Wu, Yu-Chang Bryan; Silva O’Hare, Joselli; Martin, Victoria; Kipling, David; Fraternali, Franca; Dunn-Walters, Deborah K.
2016-01-01
Antibody variable regions are composed of a heavy and a light chain, and in humans, there are two light chain isotypes: kappa and lambda. Despite their importance in receptor editing, the light chain is often overlooked in the antibody literature, with the focus being on the heavy chain complementarity-determining region (CDR)-H3 region. In this paper, we set out to investigate the physicochemical and structural differences between human kappa and lambda light chain CDR regions. We constructed a dataset containing over 29,000 light chain variable region sequences from IgM-transcribing, newly formed B cells isolated from human bone marrow and peripheral blood. We also used a published human naïve dataset to investigate the CDR-H3 properties of heavy chains paired with kappa and lambda light chains and probed the Protein Data Bank to investigate the structural differences between kappa and lambda antibody CDR regions. We found that kappa and lambda light chains have very different CDR physicochemical and structural properties, whereas the heavy chains with which they are paired do not differ significantly. We also observed that the mean CDR3 N nucleotide addition in the kappa, lambda, and heavy chain gene rearrangements are correlated within donors but can differ between donors. This indicates that terminal deoxynucleotidyl transferase may work with differing efficiencies between different people but the same efficiency in the different classes of immunoglobulin chain within one person. We have observed large differences in the physicochemical and structural properties of kappa and lambda light chain CDR regions. This may reflect different roles in the humoral immune response. PMID:27729912
Fluorescence spectroscopy for rapid detection and classification of bacterial pathogens.
Sohn, Miryeong; Himmelsbach, David S; Barton, Franklin E; Fedorka-Cray, Paula J
2009-11-01
This study deals with the rapid detection and differentiation of Escherichia coli, Salmonella, and Campylobacter, which are the most commonly identified commensal and pathogenic bacteria in foods, using fluorescence spectroscopy and multivariate analysis. Each bacterial sample cultured under controlled conditions was diluted in physiologic saline for analysis. Fluorescence spectra were collected over a range of 200-700 nm with 0.5 nm intervals on the PerkinElmer Fluorescence Spectrometer. The synchronous scan technique was employed to find the optimum excitation (lambda(ex)) and emission (lambda(em)) wavelengths for individual bacteria with the wavelength interval (Deltalambda) being varied from 10 to 200 nm. The synchronous spectra and two-dimensional plots showed two maximum lambda(ex) values at 225 nm and 280 nm and one maximum lambda(em) at 335-345 nm (lambda(em) = lambda(ex) + Deltalambda), which correspond to the lambda(ex) = 225 nm, Deltalambda = 110-120 nm, and lambda(ex) = 280 nm, Deltalambda = 60-65 nm. For all three bacterial genera, the same synchronous scan results were obtained. The emission spectra from the three bacteria groups were very similar, creating difficulty in classification. However, the application of principal component analysis (PCA) to the fluorescence spectra resulted in successful classification of the bacteria by their genus as well as determining their concentration. The detection limit was approximately 10(3)-10(4) cells/mL for each bacterial sample. These results demonstrated that fluorescence spectroscopy, when coupled with PCA processing, has the potential to detect and to classify bacterial pathogens in liquids. The methodology is rapid (>10 min), inexpensive, and requires minimal sample preparation compared to standard analytical methods for bacterial detection.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Aaij, R.; Bauer, Th.; Beuzekom, M. van
Branching fractions of the decays H{sub b}{yields}H{sub c}{pi}{sup -}{pi}{sup +}{pi}{sup -} relative to H{sub b}{yields}H{sub c}{pi}{sup -} are presented, where H{sub b} (H{sub c}) represents B{sup 0} (D{sup +}), B{sup -} (D{sup 0}), B{sub s}{sup 0} (D{sub s}{sup +}), and {Lambda}{sub b}{sup 0} ({Lambda}{sub c}{sup +}). The measurements are performed with the LHCb detector using 35 pb{sup -1} of data collected at {radical}(s)=7 TeV. The ratios of branching fractions are measured to be [B(B{sup 0}{yields}D{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -})]/[B(B{sup 0}{yields}D{sup +}{pi}{sup -})]=2.38{+-}0.11{+-}0.21, [B(B{sup -}{yields}D{sup 0}{pi}{sup -}{pi}{sup +}{pi}{sup -})]/[B(B{sup -}{yields}D{sup 0}{pi}{sup -})]= 1.27{+-}0.06{+-}0.11, [B(B{sub s}{sup 0}{yields}D{sub s}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -})]/[B(B{submore » s}{sup 0}{yields}D{sub s}{sup +}{pi}{sup -})]=2.01{+-}0.37{+-}0.20, [B({Lambda}{sub b}{sup 0}{yields}{Lambda}{sub c}{sup +}{pi}{sup -} {pi}{sup +}{pi}{sup -})]/[B({Lambda}{sub b}{sup 0}{yields}{Lambda}{sub c}{sup +}{pi}{sup -})]=1.43{+-}0.16{+-}0.13 We also report measurements of partial decay rates of these decays to excited charm hadrons. These results are of comparable or higher precision than existing measurements.« less
RAMAN SCATTERED He II {lambda}4332 IN THE SYMBIOTIC STAR V1016 CYGNI
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lee, Hee-Won
Raman scattering of He II line photons with atomic hydrogen is important in studying the mass loss processes in many symbiotic stars and a number of young planetary nebulae. We calculate the scattering cross sections and branching ratios associated with the Raman scattered He II {lambda}4332 feature formed through inelastic scattering of He II {lambda}949 with a hydrogen atom. At the line center of He II {lambda}949, the total scattering cross section is computed to be {sigma}{sub tot} = 2.5 Multiplication-Sign 10{sup -22} cm{sup 2}, and the branching ratio into the level 2s is 0.12. We also present a high-resolutionmore » spectrum of the symbiotic star V1016 Cygni obtained with the 1.8 m telescope at Mt. Bohyun to investigate the Raman scattering origin of the broad feature blueward of He II {lambda}4338. Based on the atomic calculation, we perform Monte Carlo calculations for the line formation. The scattering region is assumed to be a part of a uniform spherical shell that subtends a solid angle {Delta}{Omega} = {pi} steradian with a neutral column density N{sub HI} = 1.0 x 10{sup 21} cm{sup -2}. By adding a far-UV continuum around He II {lambda}949 normalized by the equivalent width of He II {lambda}949 to be 2.3 Angstrom-Sign , we obtain a good fit for both the Raman scattered He II {lambda}4332 and the broad wings around H{gamma}. Our analysis of the Raman feature blueward of H{gamma} in V1016 Cyg is consistent with the previous study of the Raman features blueward of H{alpha} and H{beta} by Jung and Lee.« less
Distributed modeling of diffusive solute transport in peritoneal dialysis.
Waniewski, Jacek
2002-01-01
The diffusive transport between blood and an ex-tissue medium (dialysis fluid) is evaluated using a mathematical model that takes into account the (quasicontinuous) distribution of capillaries within the tissue at various distances from the tissue surface, and includes diffusive-convective transport through the capillary wall and lymphatic absorption from the tissue. General formulas for solute penetration depth, lambda, and for the diffusive mass transport coefficient for the transport between blood and dialysis fluid, K(BD), are provided in terms of local transport coefficients for capillary wall, tissue, and lymphatic absorption. For pure diffusive transport between blood and dialysis fluid and thick tissue layers (i.e., if the solute penetration depth is much lower than the tissue thickness) these formulas yield previously known expressions. It is shown that apparent tissue layers, with widths lambdaTBL and lambdaT, respectively, may be defined according to the values of local transport parameters in such a way that K(BD) is equal to the solute clearance K(TBL) from the tissue by blood and lymph for a layer with width lambdaTBL or to the solute clearance K(T) from blood to dialysate by diffusion through the tissue layer with width lambdaT. For tissue layers with width much higher than the penetration depth: lambdaT approximately = lambdaTBL approximately = lambda. These characteristic width lengths depend on the transport parameters (and thus on the size) of solutes. Effective blood flow, which may be related to the exchange of the solute between blood and dialysate, is defined using an analogy to the extraction/absorption coefficients for blood-tissue exchange. Various approximations for the distributed model formula for diffusive mass transport coefficient (K(BD)) are possible. The appropriate range for their application is obtained from the general formula.
Fitting the constitution type Ia supernova data with the redshift-binned parametrization method
DOE Office of Scientific and Technical Information (OSTI.GOV)
Huang Qingguo; Kavli Institute for Theoretical Physics China, Chinese Academy of Sciences, Beijing 100190; Li Miao
2009-10-15
In this work, we explore the cosmological consequences of the recently released Constitution sample of 397 Type Ia supernovae (SNIa). By revisiting the Chevallier-Polarski-Linder (CPL) parametrization, we find that, for fitting the Constitution set alone, the behavior of dark energy (DE) significantly deviates from the cosmological constant {lambda}, where the equation of state (EOS) w and the energy density {rho}{sub {lambda}} of DE will rapidly decrease along with the increase of redshift z. Inspired by this clue, we separate the redshifts into different bins, and discuss the models of a constant w or a constant {rho}{sub {lambda}} in each bin,more » respectively. It is found that for fitting the Constitution set alone, w and {rho}{sub {lambda}} will also rapidly decrease along with the increase of z, which is consistent with the result of CPL model. Moreover, a step function model in which {rho}{sub {lambda}} rapidly decreases at redshift z{approx}0.331 presents a significant improvement ({delta}{chi}{sup 2}=-4.361) over the CPL parametrization, and performs better than other DE models. We also plot the error bars of DE density of this model, and find that this model deviates from the cosmological constant {lambda} at 68.3% confidence level (CL); this may arise from some biasing systematic errors in the handling of SNIa data, or more interestingly from the nature of DE itself. In addition, for models with same number of redshift bins, a piecewise constant {rho}{sub {lambda}} model always performs better than a piecewise constant w model; this shows the advantage of using {rho}{sub {lambda}}, instead of w, to probe the variation of DE.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chistov, R.; Aushev, T.; Balagura, V.
We report the first observation of the decay B{sup +}{yields}{xi}{sub c}{sup 0}{lambda}{sub c}{sup +} with a significance of 8.7{sigma} and evidence for the decay B{sup 0}{yields}{xi}{sub c}{sup -}{lambda}{sub c}{sup +} with a significance of 3.8{sigma}. The product B(B{sup +}{yields}{xi}{sub c}{sup 0}{lambda}{sub c}{sup +})xB({xi}{sub c}{sup 0}{yields}{xi}{sup +}{pi}{sup -}) is measured to be (4.8{sub -0.9}{sup +1.0}{+-}1.1{+-}1.2)x10{sup -5}, and B(B{sup 0}{yields}{xi}{sub c}{sup -}{lambda}{sub c}{sup +})xB({xi}{sub c}{sup -}{yields}{xi}{sup +}{pi}{sup -}{pi}{sup -}) is measured to be (9.3{sub -2.8}{sup +3.7}{+-}1.9{+-}2.4)x10{sup -5}. The errors are statistical, systematic and the error of the {lambda}{sub c}{sup +}{yields}pK{sup -}{pi}{sup +} branching fraction, respectively. The decay B{sup +}{yields}{xi}{sub c}{sup 0}{lambda}{sub c}{supmore » +} is the first example of a two-body exclusive B{sup +} decay into two charmed baryons. The data used for this analysis was accumulated at the {upsilon}(4S) resonance, using the Belle detector at the e{sup +}e{sup -} asymmetric-energy collider KEKB. The integrated luminosity of the data sample is equal to 357 fb{sup -1}, corresponding to 386x10{sup 6} BB pairs.« less
Linear Polarization Measurements of Chromospheric Emission Lines
NASA Technical Reports Server (NTRS)
Sheeley, N. R., Jr.; Keller, C. U.
2003-01-01
We have used the Zurich Imaging Stokes Polarimeter (ZIMPOL I) with the McMath-Pierce 1.5 m main telescope on Kitt Peak to obtain linear polarization measurements of the off-limb chromosphere with a sensitivity better than 1 x 10(exp -5). We found that the off-disk observations require a combination of good seeing (to show the emission lines) and a clean heliostat (to avoid contamination by scattered light from the Sun's disk). When these conditions were met, we obtained the following principal results: 1. Sometimes self-reversed emission lines of neutral and singly ionized metals showed linear polarization caused by the transverse Zeeman effect or by instrumental cross talk from the longitudinal Zeeman effect in chromospheric magnetic fields. Otherwise, these lines tended to depolarize the scattered continuum radiation by amounts that ranged up to 0.2%. 2. Lines previously known to show scattering polarization just inside the limb (such as the Na I lambda5889 D2 and the He I lambda5876 D3 lines) showed even more polarization above the Sun's limb, with values approaching 0.7%. 3. The O I triplet at lambda7772, lambda7774, and lambda7775 showed a range of polarizations. The lambda7775 line, whose maximum intrinsic polarizability, P(sub max), is less than 1%, revealed mainly Zeeman contributions from chromospheric magnetic fields. However, the more sensitive lambda7772 (P(sub max) = 19%) and lambda7774 (P(sub max) = 29%) lines had relatively strong scattering polarizations of approximately 0.3% in addition to their Zeeman polarizations. At times of good seeing, the polarization spectra resolve into fine structures that seem to be chromospheric spicules.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Cheng, Kwang-Ping; Johnson, Dustin M.; Tarbell, Erik S.
Since the peculiar nature of Lambda Boötis was first noticed in 1943, the Lambda Boo stars have been recognized as a group of peculiar A-type stars. They are Population I dwarfs that show deficiencies of iron-peak elements (up to 2 dex), but have near-solar C, N, O, and S abundances. In a previous paper, we used both observed and synthetic ultraviolet spectra to demonstrate that the C i 1657 Å/Al ii 1671 Å equivalent width ratio can help distinguish between Lambda Boo stars and other metal-weak stars hotter than 8000 K. In this paper, using observed and synthetic visible (4000–6800more » Å) spectra, we demonstrate that the C i 5052.17 Å/Mg ii 4481 Å equivalent width ratio can be used as a quantitative diagnostic for cooler Lambda Boo stars.« less
Refractive index and birefringence of 2H silicon carbide.
NASA Technical Reports Server (NTRS)
Powell, J. A.
1972-01-01
Measurement of the refractive indices of 2H SiC over the wavelength range from 435.8 to 650.9 nm by the method of minimum deviation. A curve fit of the experimental data to the Cauchy dispersion equation yielded, for the ordinary index, n sub zero = 2.5513 + 25,850/lambda squared + 8.928 x 10 to the 8th power/lambda to the 4th power and, for the extraordinary index, n sub e = 2.6161 + 28,230/lambda squared + 11.490 x 10 to the 8th power/lambda to the 4th power when lambda is expressed in nm. The estimated error (standard deviation) in these values is plus or minus 0.0006 for n sub zero and plus or minus 0.0009 for n sub e. The birefringence calculated from these expressions is about 20% less than previously published values.
Residues of lambda-cyhalothrin in tea.
Seenivasan, Subbiah; Muraleedharan, Narayanan Nair
2009-02-01
Field experiments were conducted at two places in Tamil Nadu (India) during dry season of 2006 to determine the residues of lambda-cyhalothrin in fresh green tea leaves and black tea. Residues were quantified at different harvest intervals of '0' (3h), 1st, 3rd, 5th, 7th, 10th and 14th day after insecticide application. Persistence, dissipation pattern, half-life value and safe harvest interval of the insecticide in tea were calculated. Residues of lambda-cyhalothrin dissipated exponentially after application at both the locations and reached below the European Union maximum residue limit (MRL) of 1mg/kg on the 5th day. Lambda-cyhalothrin showed that like other insecticides it followed the first order dissipation kinetics. Half-life values varied from 2.8 to 3.5 days for lambda-cyhalothrin and a safety harvest interval of 5 days is suggested for tea at the recommended dosage.
NASA Astrophysics Data System (ADS)
Cheng, Kwang-Ping; Neff, James E.; Johnson, Dustin M.; Tarbell, Erik S.; Romo, Christopher A.; Gray, Richard O.; Corbally, Christopher J.
2017-01-01
Since the peculiar nature of Lambda Boötis was first noticed in 1943, the Lambda Boo stars have been recognized as a group of peculiar A-type stars. They are Population I dwarfs that show deficiencies of iron-peak elements (up to 2 dex), but have near-solar C, N, O, and S abundances. In a previous paper, we used both observed and synthetic ultraviolet spectra to demonstrate that the C I 1657 Å/Al II 1671 Å equivalent width ratio can help distinguish between Lambda Boo stars and other metal-weak stars hotter than 8000 K. In this paper, using observed and synthetic visible (4000-6800 Å) spectra, we demonstrate that the C I 5052.17 Å/Mg II 4481 Å equivalent width ratio can be used as a quantitative diagnostic for cooler Lambda Boo stars.
Photon induced {lambda}(1520) production and the role of the K* exchange
DOE Office of Scientific and Technical Information (OSTI.GOV)
Toki, Hiroshi; Research Center for Nuclear Physics; Garcia-Recio, Carmen
2008-02-01
We study the photon induced {lambda}(1520) production in the effective Lagrangian method near threshold, E{sub {gamma}}{sup LAB}{<=}2 GeV, and in the quark-gluon string model at higher energies 3 GeV{<=}E{sub {gamma}}{sup LAB}{<=}5 GeV. In particular, we study the role of the K* exchange for the production of {lambda}(1520) within the SU(6) Weinberg-Tomozowa chiral unitary model proposed by Garcia-Recio, Nieves, and Salcedo [Phys. Rev. D 74, 034025 (2006)]. The coupling of the {lambda}(1520) resonance to the NK* pair, which is dynamically generated, turns out to be relatively small and, thus, the K exchange mechanism dominates the reaction. In the higher energy region,more » where experimental data are available, the quark-gluon string mechanism with the K Regge trajectory reproduces both the energy and the angular distribution dependences of the {lambda}(1520) photoproduction reaction.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Steph, N.C.; Golden, D.E.
1983-03-01
Electron-photon angular correlations between electrons which have excited the 2/sup 1/P state of He and photons from the 2/sup 1/P..-->..1/sup 1/S transition have been studied for 27-, 30-, 35-, and 40-eV incident electrons. Values of lambda and Vertical BarchiVertical Bar obtained from these measurements are compared to values obtained in distorted-wave and R-matrix calculations. The values of lambda and Vertical BarchiVertical Bar have been combined to examine the behavior of Vertical BarO/sub 1//sub -//sup colvertical-bar/ (lambda(1-lambda)sinVertical BarchiVertical Bar), the nonvanishing component of orientation. At 27 eV, a substantial decrease was observed in the values of lambda and Vertical BarO/sub 1//submore » -//sup colvertical-bar/, compared with their values for E> or =30 eV.« less
Picken, M. M.; Gallo, G.; Buxbaum, J.; Frangione, B.
1986-01-01
Amyloid fibrils were extracted from the kidney of a patient (CHE) shown to have tetramers and dimers of a monoclonal lambda light chain in his serum, and whose bone marrow cells in short-term culture synthesized these forms and a smaller lambda fragment of approximately 10,000 to 12,000 daltons. Biochemical and serologic analysis of a fraction of a size (obtained from amyloid fibrils extracted from the kidney) similar to that synthesized by the bone marrow cells revealed a light chain fragment corresponding to the amino terminal end of the variable region of the lambda light chain subgroup II. The presence of similarly sized short fragments of lambda light chain in both the synthesized and deposited protein suggests that aberrant synthesis and/or proteolytic degradation may play a pathogenetic role in the process of amyloidogenesis. Images Figure 1 PMID:3089021
Kondoh, H; Paul, B R; Howe, M M
1980-09-01
A general method for constructing lambda specialized transducing phages is described. The method, which is potentially applicable to any gene of Escherichia coli, is based on using Mu DNA homology to direct the integration of a lambda pMu phage near the genes whose transduction is desired. With this method we isolated a lambda transducing phage carrying all 10 genes in the che gene cluster (map location, 41.5 to 42.5 min). The products of the cheA and tar genes were identified by using transducing phages with amber mutations in these genes. It was established that tar codes for methyl-accepting chemotaxis protein II (molecular weight, 62,000) and that cheA codes for two polypeptides (molecular weights, 76,000 and 66,000). Possible origins of the two cheA polypeptides are discussed.
Effects of cross-correlated noises on the relaxation time of the bistable system
NASA Astrophysics Data System (ADS)
Xie, Chong-Wei; Mei, Dong-Cheng
2003-11-01
The stationary correlation function and the associated relaxation time for a general system driven by cross-correlated white noises are derived, by virtue of a Stratonovich-like ansatz. The effects of correlated noises on the relaxation time of a bistable kinetic model coupled to an additive and a multiplicative white noises are studied. It is proved that for small fluctuations the relaxation time Tc as a function of lambda (the correlated intensity between noises) exhibits very different behaviours for alpha
[Spectral sensitivity and visual pigments of the coastal crab Hemigrapsus sanguineus].
Shukoliukov, S A; Zak, P P; Kalamkarov, G R; Kalishevich, O O; Ostrovskiĭ, M A
1980-01-01
It has been shown that the compound eye of the coastal crab has one photosensitive pigment rhodopsin and screening pigments, black and orange one. The orange pigment has lambda max = 480 nm, rhodopsin in digitonin is stable towards hydroxylamin action, has lambda max = 490-495 nm and after bleaching is transformed into free retinene and opsin. The pigments with lambda max = 430 and 475 nm of the receptor part of the eye are also solubilized. These pigments are not photosensitive but they dissociate under the effect of hydroxylamine. The curye of spectral sensitivity of the coastal crab has the basic maximum at approximately 525 nm and the additional one at 450 nm, which seems to be provided by a combination of the visual pigment--rhodopsin (lambda max 500 nm) with a carotinoid filter (lambda max 480-490). Specific features of the visual system of coastal crab are discussed.
Abazov, V M; Abbott, B; Abolins, M; Acharya, B S; Adams, M; Adams, T; Aguilo, E; Ahn, S H; Ahsan, M; Alexeev, G D; Alkhazov, G; Alton, A; Alverson, G; Alves, G A; Anastasoaie, M; Ancu, L S; Andeen, T; Anderson, S; Andrieu, B; Anzelc, M S; Arnoud, Y; Arov, M; Askew, A; Asman, B; Assis Jesus, A C S; Atramentov, O; Autermann, C; Avila, C; Ay, C; Badaud, F; Baden, A; Bagby, L; Baldin, B; Bandurin, D V; Banerjee, P; Banerjee, S; Barberis, E; Barfuss, A-F; Bargassa, P; Baringer, P; Barnes, C; Barreto, J; Bartlett, J F; Bassler, U; Bauer, D; Beale, S; Bean, A; Begalli, M; Begel, M; Belanger-Champagne, C; Bellantoni, L; Bellavance, A; Benitez, J A; Beri, S B; Bernardi, G; Bernhard, R; Berntzon, L; Bertram, I; Besançon, M; Beuselinck, R; Bezzubov, V A; Bhat, P C; Bhatnagar, V; Binder, M; Biscarat, C; Blackler, I; Blazey, G; Blekman, F; Blessing, S; Bloch, D; Bloom, K; Boehnlein, A; Boline, D; Bolton, T A; Boos, E E; Borissov, G; Bos, K; Bose, T; Brandt, A; Brock, R; Brooijmans, G; Bross, A; Brown, D; Buchanan, N J; Buchholz, D; Buehler, M; Buescher, V; Bunichev, V; Burdin, S; Burke, S; Burnett, T H; Busato, E; Buszello, C P; Butler, J M; Calfayan, P; Calvet, S; Cammin, J; Caron, S; Carvalho, W; Casey, B C K; Cason, N M; Castilla-Valdez, H; Chakrabarti, S; Chakraborty, D; Chan, K; Chan, K M; Chandra, A; Charles, F; Cheu, E; Chevallier, F; Cho, D K; Choi, S; Choudhary, B; Christofek, L; Christoudias, T; Claes, D; Clément, B; Clément, C; Coadou, Y; Cooke, M; Cooper, W E; Corcoran, M; Couderc, F; Cousinou, M-C; Cox, B; Crépé-Renaudin, S; Cutts, D; Cwiok, M; da Motta, H; Das, A; Davies, B; Davies, G; De, K; de Jong, P; de Jong, S J; De La Cruz-Burelo, E; De Oliveira Martins, C; Degenhardt, J D; Déliot, F; Demarteau, M; Demina, R; Denisov, D; Denisov, S P; Desai, S; Diehl, H T; Diesburg, M; Doidge, M; Dominguez, A; Dong, H; Dudko, L V; Duflot, L; Dugad, S R; Duggan, D; Duperrin, A; Dyer, J; Dyshkant, A; Eads, M; Edmunds, D; Ellison, J; Elvira, V D; Enari, Y; Eno, S; Ermolov, P; Evans, H; 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Zielinski, M; Zieminska, D; Zieminski, A; Zutshi, V; Zverev, E G
2007-11-09
We search for the production of single top quarks via flavor-changing-neutral-current couplings of a gluon to the top quark and a charm (c) or up (u) quark. We analyze 230 pb{-1} of lepton+jets data from pp[over] collisions at a center of mass energy of 1.96 TeV collected by the D0 detector at the Fermilab Tevatron Collider. We observe no significant deviation from standard model predictions, and hence set upper limits on the anomalous coupling parameters kappa{g}{c}/Lambda and kappa{g}{u}/Lambda, where kappa{g} define the strength of tcg and tug couplings, and Lambda defines the scale of new physics. The limits at 95% C.L. are kappa{g}{c}/Lambda<0.15 TeV-1 and kappa{g}{u}/Lambda<0.037 TeV-1.